# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SOCS_box PF07525.16 KER17977.1 - 0.0047 17.2 2.3 0.0087 16.4 2.3 1.4 1 0 0 1 1 1 1 SOCS box SOGA PF11365.8 KER17986.1 - 8.9e-06 26.8 21.1 0.0014 19.8 5.1 1.9 1 1 1 2 2 2 2 Protein SOGA Macoilin PF09726.9 KER17986.1 - 0.003 16.2 6.4 0.003 16.2 6.4 1.0 1 0 0 1 1 1 1 Macoilin family TPR_MLP1_2 PF07926.12 KER17986.1 - 0.02 15.0 11.8 0.053 13.6 1.5 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Borrelia_P83 PF05262.11 KER17986.1 - 0.033 12.7 2.6 0.037 12.5 2.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ARS2 PF04959.13 KER17986.1 - 0.064 13.6 1.8 0.065 13.6 1.8 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DUF4226 PF10774.9 KER17986.1 - 0.069 13.4 1.9 0.079 13.2 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) PIEZO PF15917.5 KER17986.1 - 0.1 12.1 3.7 0.11 12.0 3.7 1.0 1 0 0 1 1 1 0 Piezo APG6_N PF17675.1 KER17986.1 - 0.24 11.9 11.4 0.25 11.9 11.4 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2948 PF11164.8 KER17988.1 - 0.11 12.6 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) RRM_1 PF00076.22 KER17989.1 - 1.4e-08 34.4 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER17989.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif THP2 PF09432.10 KER17992.1 - 0.056 13.5 0.1 0.058 13.5 0.1 1.0 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF2841 PF11001.8 KER17994.1 - 0.023 14.7 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) EF-hand_1 PF00036.32 KER17996.1 - 1.8e-07 30.2 0.1 2.4e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER17996.1 - 2.8e-07 29.9 0.3 3.9e-07 29.5 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KER17996.1 - 3.3e-07 29.5 0.2 4.8e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KER17996.1 - 7.8e-05 23.1 0.0 8.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER17996.1 - 0.024 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair ACT_7 PF13840.6 KER17998.1 - 0.056 13.2 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 ACT domain GDA1_CD39 PF01150.17 KER18000.1 - 4.9e-17 61.7 0.0 5.6e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2039 PF10217.9 KER18002.1 - 8.6e-18 64.5 1.1 9.7e-18 64.3 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Histone PF00125.24 KER18006.1 - 1.1e-10 42.0 0.2 1.4e-10 41.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER18006.1 - 0.035 14.4 0.3 0.058 13.7 0.1 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER18006.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A SYF2 PF08231.12 KER18007.1 - 1.5e-27 96.9 1.7 1.8e-27 96.7 1.7 1.0 1 0 0 1 1 1 1 SYF2 splicing factor Aldedh PF00171.22 KER18007.1 - 0.12 10.8 0.2 0.12 10.8 0.2 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Tubulin PF00091.25 KER18010.1 - 5.3e-15 56.1 0.0 5.7e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KER18010.1 - 0.0021 17.3 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin like Defensin_int PF17858.1 KER18013.1 - 0.0016 18.4 1.0 0.0016 18.4 1.0 1.8 2 0 0 2 2 2 1 Platypus intermediate defensin-like peptide GATA PF00320.27 KER18015.1 - 0.044 13.4 1.3 0.064 12.9 1.3 1.3 1 0 0 1 1 1 0 GATA zinc finger Tektin PF03148.14 KER18018.1 - 4.7e-16 58.5 0.9 5e-16 58.4 0.9 1.0 1 0 0 1 1 1 1 Tektin family Apolipoprotein PF01442.18 KER18018.1 - 0.0019 18.1 0.5 0.0022 17.9 0.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CdvA PF18822.1 KER18018.1 - 0.022 14.6 0.1 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 CdvA-like coiled-coil domain SpoIIID PF12116.8 KER18018.1 - 0.058 13.5 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 Stage III sporulation protein D SYCE1 PF15233.6 KER18018.1 - 0.086 12.9 0.1 0.093 12.8 0.1 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 PyocinActivator PF11112.8 KER18022.1 - 0.028 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyocin activator protein PrtN Sec7 PF01369.20 KER18023.1 - 5.4e-11 42.5 0.0 6.2e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain DUF2789 PF10982.8 KER18023.1 - 0.18 12.0 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) RhoGAP PF00620.27 KER18028.1 - 0.023 14.5 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 RhoGAP domain Myotub-related PF06602.14 KER18036.1 - 0.003 16.5 0.0 0.0031 16.5 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain NADPH_Ox PF08414.10 KER18038.1 - 0.087 13.2 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase GSHPx PF00255.19 KER18038.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione peroxidase GoLoco PF02188.17 KER18040.1 - 0.15 11.6 8.8 0.4 10.3 0.8 2.7 3 0 0 3 3 3 0 GoLoco motif Peptidase_M3 PF01432.20 KER18046.1 - 1.5e-15 57.4 0.1 1.7e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M3 eIF3g PF12353.8 KER18047.1 - 1.2e-19 70.9 0.3 1.4e-19 70.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G AAA_7 PF12775.7 KER18049.1 - 1.1e-17 64.2 0.3 1.2e-17 64.0 0.3 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KER18049.1 - 2e-05 24.9 0.1 2.7e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER18049.1 - 0.00024 21.5 0.0 0.00035 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KER18049.1 - 0.00093 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KER18049.1 - 0.0029 17.6 0.0 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 KER18049.1 - 0.0048 16.1 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KER18049.1 - 0.0075 16.0 0.0 0.0098 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KER18049.1 - 0.0086 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KER18049.1 - 0.012 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KER18049.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KER18049.1 - 0.024 15.1 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KER18049.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.3 1 1 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 KER18049.1 - 0.034 13.8 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KER18049.1 - 0.035 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KER18049.1 - 0.044 13.7 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 KER18049.1 - 0.044 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KER18049.1 - 0.071 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 KER18049.1 - 0.076 12.2 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KER18049.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Integrin_alpha2 PF08441.12 KER18053.1 - 2.5e-08 33.2 0.0 2.5e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha Aldedh PF00171.22 KER18054.1 - 7.4e-26 90.7 0.0 8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ABC_tran PF00005.27 KER18057.1 - 8.9e-07 29.5 0.0 1.2e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 KER18057.1 - 0.00077 19.6 0.0 0.00077 19.6 0.0 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KER18057.1 - 0.001 19.1 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KER18057.1 - 0.013 14.6 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KER18057.1 - 0.05 14.0 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KER18057.1 - 0.092 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 KER18057.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 AIG1 family AAA_23 PF13476.6 KER18057.1 - 0.18 12.3 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KER18057.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KER18057.1 - 0.21 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Gtr1_RagA PF04670.12 KER18057.1 - 0.23 10.8 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynein_light PF01221.18 KER18061.1 - 8.5e-15 54.9 0.0 9.5e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 E2F_TDP PF02319.20 KER18061.1 - 0.048 13.7 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain MetOD2 PF18548.1 KER18061.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Metanogen output domain 2 SAP PF02037.27 KER18062.1 - 1.6e-09 37.3 3.8 2e-09 37.0 3.8 1.1 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 KER18062.1 - 0.01 15.7 0.7 0.014 15.3 0.7 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain zf-RanBP PF00641.18 KER18066.1 - 0.026 13.9 5.8 0.026 13.9 5.8 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pro-kuma_activ PF09286.11 KER18068.1 - 0.0028 18.0 0.0 0.0036 17.6 0.0 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HD_6 PF18019.1 KER18068.1 - 0.057 13.5 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 HD domain RabGAP-TBC PF00566.18 KER18070.1 - 8.2e-15 55.0 0.3 9e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA_int_endo PF01974.17 KER18073.1 - 6.5e-11 42.1 0.1 8.8e-11 41.7 0.1 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Integrase_H2C2 PF17921.1 KER18076.1 - 5.4e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KER18076.1 - 0.00043 20.5 0.4 0.00062 20.0 0.4 1.3 1 1 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KER18076.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_L15e PF00827.17 KER18076.1 - 0.014 15.1 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal L15 GST_C_2 PF13410.6 KER18076.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain IQ PF00612.27 KER18077.1 - 4.5e-10 38.4 1.8 2.7e-07 29.8 0.1 2.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif ORC6 PF05460.13 KER18079.1 - 9.7 5.3 10.2 11 5.2 10.2 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Parvo_NS1 PF01057.17 KER18081.1 - 0.00018 20.7 0.2 0.00021 20.5 0.2 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18081.1 - 0.0011 18.0 0.1 0.0012 17.8 0.1 1.0 1 0 0 1 1 1 1 Papillomavirus helicase HD_3 PF13023.6 KER18081.1 - 0.06 13.3 0.1 0.074 13.0 0.1 1.1 1 0 0 1 1 1 0 HD domain T2SSE PF00437.20 KER18081.1 - 0.14 11.1 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Vault_4 PF17796.1 KER18084.1 - 6.9e-31 106.1 0.0 1.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Major Vault Protein repeat domain Vault PF01505.18 KER18084.1 - 3e-08 33.7 0.1 2.9e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Major Vault Protein repeat domain Glyco_hydro_38C PF07748.13 KER18085.1 - 0.011 15.8 0.0 0.012 15.6 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain NPC1_N PF16414.5 KER18086.1 - 2.2e-12 47.1 0.2 2.3e-12 47.0 0.2 1.0 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus DYW_deaminase PF14432.6 KER18087.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Kelch_1 PF01344.25 KER18091.1 - 1.8e-28 97.8 1.8 3.1e-11 42.7 0.0 3.0 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KER18091.1 - 1e-16 60.5 2.3 3.4e-07 30.3 0.0 3.1 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 KER18091.1 - 1.8e-12 46.7 0.1 4e-07 29.8 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KER18091.1 - 1.1e-08 35.1 7.1 0.0003 21.0 0.1 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KER18091.1 - 1.4e-06 28.2 1.7 0.023 14.7 0.0 2.9 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KER18091.1 - 2.2e-05 24.3 3.1 0.28 11.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif PQQ_3 PF13570.6 KER18091.1 - 0.00056 20.3 0.4 4.6 7.9 0.0 3.1 3 0 0 3 3 3 2 PQQ-like domain EF-hand_7 PF13499.6 KER18093.1 - 1.7e-08 34.8 0.1 1.7e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER18093.1 - 3.3e-06 26.3 0.2 4.5e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER18093.1 - 2.1e-05 24.1 0.1 3.1e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain DUF1456 PF07308.13 KER18093.1 - 0.00027 21.2 0.1 0.00029 21.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1456) EF-hand_5 PF13202.6 KER18093.1 - 0.0012 18.3 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KER18093.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 KER18093.1 - 0.015 15.2 0.1 0.016 15.0 0.1 1.0 1 0 0 1 1 1 0 EF hand HrpE PF06188.12 KER18093.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.0 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E HTH_12 PF08461.10 KER18093.1 - 0.18 11.7 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain tRNA-synt_1 PF00133.22 KER18094.1 - 1.4e-08 33.4 0.0 1.5e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KER18094.1 - 0.0073 15.7 0.0 0.0073 15.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KER18094.1 - 0.0079 15.0 0.0 0.0082 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KER18094.1 - 0.04 12.8 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) MVP_shoulder PF11978.8 KER18095.1 - 1e-10 41.7 0.2 1.6e-10 41.0 0.1 1.4 2 0 0 2 2 2 1 Shoulder domain DUF2543 PF10820.8 KER18095.1 - 0.035 14.3 0.0 0.038 14.2 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2543) Tipalpha PF16753.5 KER18095.1 - 0.052 13.4 0.1 0.057 13.2 0.1 1.0 1 0 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter Peptidase_M61_N PF17899.1 KER18097.1 - 0.067 13.3 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain Hfq PF17209.3 KER18097.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Hfq protein ADP_ribosyl_GH PF03747.14 KER18107.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase FrhB_FdhB_C PF04432.13 KER18109.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus TRAM_LAG1_CLN8 PF03798.16 KER18111.1 - 2.4e-09 37.2 0.4 2.5e-09 37.2 0.4 1.0 1 0 0 1 1 1 1 TLC domain Raffinose_syn PF05691.12 KER18111.1 - 0.21 9.3 0.1 0.21 9.3 0.1 1.0 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Acatn PF13000.7 KER18112.1 - 6.4e-12 44.7 0.7 7.3e-12 44.6 0.7 1.1 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 zinc_ribbon_16 PF17034.5 KER18122.1 - 0.0013 18.9 10.2 0.0032 17.7 10.2 1.6 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KER18122.1 - 0.0091 15.6 13.5 0.024 14.3 13.5 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2457 PF10446.9 KER18125.1 - 0.00011 21.5 1.0 0.00014 21.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Glyco_hydro_38N PF01074.22 KER18138.1 - 5.8e-05 22.6 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KER18138.1 - 0.00041 20.4 0.1 0.00091 19.3 0.0 1.6 2 0 0 2 2 2 1 Alpha mannosidase middle domain lci PF12197.8 KER18138.1 - 0.071 12.9 0.9 0.12 12.2 0.9 1.3 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein V-set_CD47 PF08204.11 KER18140.1 - 0.037 14.0 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Multi_ubiq PF14452.6 KER18141.1 - 0.013 15.7 0.0 0.035 14.4 0.0 1.6 2 0 0 2 2 2 0 Multiubiquitin Synaptobrevin PF00957.21 KER18141.1 - 0.014 15.1 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF1043 PF06295.12 KER18141.1 - 0.087 12.8 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF1465 PF07323.12 KER18141.1 - 0.11 12.3 1.7 0.15 11.9 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF4240 PF14024.6 KER18142.1 - 0.17 12.1 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) DUF3512 PF12024.8 KER18144.1 - 0.026 14.0 0.2 0.033 13.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3512) Kelch_1 PF01344.25 KER18145.1 - 5.2e-08 32.3 0.6 0.00024 20.6 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KER18145.1 - 0.16 12.3 2.1 0.31 11.4 0.1 2.2 2 1 0 2 2 2 0 Kelch motif GoLoco PF02188.17 KER18146.1 - 8.9e-10 37.9 0.2 1.3e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 GoLoco motif Dynein_light PF01221.18 KER18147.1 - 1e-08 35.3 1.3 1.6e-08 34.7 1.3 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Thioredoxin_8 PF13905.6 KER18147.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Sporozoite_P67 PF05642.11 KER18150.1 - 5 5.1 16.7 9 4.2 16.7 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen MAP65_ASE1 PF03999.12 KER18154.1 - 0.051 12.3 5.0 0.053 12.2 5.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RNA_pol_3_Rpc31 PF11705.8 KER18155.1 - 3 8.0 21.9 0.04 14.2 15.0 1.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PilM_2 PF11104.8 KER18157.1 - 0.073 12.1 0.0 0.079 12.0 0.0 1.0 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; zf-C4_ClpX PF06689.13 KER18157.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 ClpX C4-type zinc finger WBS_methylT PF12589.8 KER18159.1 - 0.019 15.7 1.9 0.022 15.5 1.9 1.1 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome eIF-6 PF01912.18 KER18160.1 - 2.8e-15 56.2 0.0 3.1e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 eIF-6 family EGF_2 PF07974.13 KER18162.1 - 0.0017 18.7 11.1 0.0026 18.1 11.1 1.3 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 KER18162.1 - 0.0019 18.5 5.0 0.0021 18.3 5.0 1.2 1 0 0 1 1 1 1 EB module PfkB PF00294.24 KER18163.1 - 3e-21 76.0 0.0 3.6e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Asparaginase_2 PF01112.18 KER18165.1 - 1.3e-14 54.0 0.1 1.3e-14 53.9 0.1 1.0 1 0 0 1 1 1 1 Asparaginase Actin PF00022.19 KER18167.1 - 4.2e-71 239.7 0.0 4.6e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Actin UDPG_MGDP_dh_N PF03721.14 KER18167.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1383 PF07134.11 KER18168.1 - 0.048 12.8 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) SOCS_box PF07525.16 KER18169.1 - 0.00047 20.4 1.7 0.0011 19.3 1.7 1.6 1 0 0 1 1 1 1 SOCS box Cpn60_TCP1 PF00118.24 KER18170.1 - 1.3e-41 142.8 1.3 1.4e-41 142.7 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3715 PF12509.8 KER18171.1 - 8.8e-14 51.7 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) Ldh_1_N PF00056.23 KER18174.1 - 2.2e-14 53.8 0.1 3.8e-14 53.0 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KER18174.1 - 1.3e-13 51.2 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Phage_holin_2_2 PF10746.9 KER18176.1 - 0.081 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II C-C_Bond_Lyase PF15617.6 KER18179.1 - 0.005 16.0 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold UPF0180 PF03698.13 KER18181.1 - 0.0077 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0180) DUF98 PF01947.16 KER18182.1 - 0.002 18.1 0.3 0.0024 17.9 0.3 1.1 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase DUF1204 PF06721.11 KER18182.1 - 0.019 14.5 0.1 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) T3SS_ATPase_C PF18269.1 KER18182.1 - 0.042 13.7 0.3 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain DUF4817 PF16087.5 KER18183.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Mito_carr PF00153.27 KER18193.1 - 2.9e-20 72.0 0.5 1.4e-12 47.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Orai-1 PF07856.12 KER18194.1 - 3.2e-18 66.0 4.6 3.8e-18 65.8 4.6 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity p53-inducible11 PF14936.6 KER18194.1 - 0.036 14.1 2.8 0.045 13.8 2.8 1.1 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF4131 PF13567.6 KER18194.1 - 0.045 13.4 1.4 0.059 13.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Adeno_E3B PF03376.14 KER18194.1 - 0.067 13.4 1.3 0.12 12.6 0.9 1.7 1 1 0 1 1 1 0 Adenovirus E3B protein DUF2207 PF09972.9 KER18194.1 - 0.13 11.0 2.7 0.15 10.8 2.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 KER18194.1 - 0.18 11.9 2.7 0.21 11.6 2.7 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2254 PF10011.9 KER18194.1 - 0.55 9.0 4.6 0.65 8.7 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Viral_Rep PF02407.16 KER18201.1 - 2.2e-10 40.7 0.0 3.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Putative viral replication protein HTH_7 PF02796.15 KER18201.1 - 0.026 14.6 0.4 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF433 PF04255.14 KER18201.1 - 0.05 13.5 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF3525 PF12039.8 KER18201.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Adaptin_N PF01602.20 KER18201.1 - 0.24 9.9 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Tubulin_C PF03953.17 KER18204.1 - 1.4e-16 60.8 0.2 1.6e-16 60.6 0.2 1.0 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF4571 PF15137.6 KER18205.1 - 0.05 13.2 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) RPGR1_C PF18111.1 KER18206.1 - 2.3e-14 53.6 0.1 3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal MEF2_binding PF09047.10 KER18206.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 MEF2 binding Kelch_1 PF01344.25 KER18207.1 - 1.4e-08 34.1 0.0 5.1e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 KER18207.1 - 6.9e-05 23.0 0.0 0.0012 19.0 0.0 2.2 1 1 1 2 2 2 1 Kelch motif Kelch_4 PF13418.6 KER18207.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 KER18207.1 - 0.029 14.4 0.0 0.095 12.7 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Muted PF14942.6 KER18208.1 - 0.04 14.3 4.9 0.044 14.1 4.9 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DHC_N1 PF08385.12 KER18209.1 - 4.9e-18 65.1 0.8 5.2e-18 65.0 0.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Sulfotransfer_3 PF13469.6 KER18211.1 - 3.9e-07 30.7 0.0 4.4e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family Asp PF00026.23 KER18212.1 - 7e-15 55.2 0.3 8.3e-15 55.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER18212.1 - 0.0037 17.5 0.1 0.62 10.3 0.0 2.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER18212.1 - 0.083 13.5 0.0 0.25 12.0 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease ABC_tran PF00005.27 KER18213.1 - 0.0016 19.0 0.0 0.0018 18.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SLC35F PF06027.12 KER18217.1 - 3.7e-25 89.1 9.3 7.6e-25 88.0 9.3 1.5 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KER18217.1 - 0.00027 20.0 1.9 0.00032 19.7 1.6 1.3 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KER18217.1 - 0.00033 20.8 14.4 0.023 14.9 7.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family Ribosomal_L32e PF01655.18 KER18219.1 - 3.1e-45 153.0 5.0 3.7e-45 152.8 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Parvo_NS1 PF01057.17 KER18220.1 - 0.00016 20.8 0.3 0.00029 20.0 0.2 1.4 1 1 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF3512 PF12024.8 KER18220.1 - 0.0032 17.0 0.2 0.0044 16.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) PPV_E1_C PF00519.17 KER18220.1 - 0.0044 15.9 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase SpoVT_C PF15714.5 KER18220.1 - 0.009 16.1 0.0 0.022 14.8 0.0 1.7 1 1 1 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor AAA_7 PF12775.7 KER18220.1 - 0.0098 15.4 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KER18220.1 - 0.042 12.9 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein V-set PF07686.17 KER18222.1 - 0.029 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF3203 PF11462.8 KER18222.1 - 0.096 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) Ig_3 PF13927.6 KER18222.1 - 0.11 13.1 0.0 0.7 10.5 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Dimerisation2 PF16864.5 KER18225.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain EMP70 PF02990.16 KER18227.1 - 1.7e-14 53.4 7.1 1.8e-14 53.3 7.1 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4131 PF13567.6 KER18227.1 - 1.8 8.2 5.5 1.9 8.2 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TPD52 PF04201.15 KER18230.1 - 0.0033 17.1 1.4 0.0043 16.7 1.2 1.3 1 1 0 1 1 1 1 Tumour protein D52 family DNA_pol_lambd_f PF10391.9 KER18231.1 - 0.062 13.1 0.6 2.1 8.2 0.1 2.6 1 1 1 2 2 2 0 Fingers domain of DNA polymerase lambda EH_Signature PF15611.6 KER18231.1 - 0.2 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain PfkB PF00294.24 KER18232.1 - 3e-19 69.4 0.0 3.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Anoctamin PF04547.12 KER18235.1 - 4.8e-06 25.7 2.1 5.1e-06 25.6 2.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Claudin_2 PF13903.6 KER18235.1 - 0.12 12.1 1.4 0.12 12.1 1.4 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Holin_BlyA PF05102.12 KER18235.1 - 0.73 9.8 4.9 0.33 10.9 2.1 1.7 2 0 0 2 2 2 0 holin, BlyA family Glyco_transf_64 PF09258.10 KER18236.1 - 1.2e-06 28.0 0.0 1.4e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Vault PF01505.18 KER18238.1 - 5.6e-12 45.6 0.0 9.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Major Vault Protein repeat domain KASH PF10541.9 KER18240.1 - 0.17 12.1 2.2 0.27 11.5 2.2 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain AA_permease_2 PF13520.6 KER18241.1 - 2.5e-13 49.6 0.9 2.7e-13 49.5 0.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER18241.1 - 0.00033 19.4 0.2 0.00033 19.4 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease zf-met PF12874.7 KER18246.1 - 0.00067 20.0 0.7 0.00067 20.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KER18246.1 - 0.1 12.2 3.4 0.13 11.8 3.4 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like AAA_6 PF12774.7 KER18247.1 - 9.6e-12 44.5 0.0 1e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 KER18247.1 - 0.0071 15.9 0.1 0.0087 15.6 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KER18247.1 - 0.028 13.8 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 KER18247.1 - 0.047 14.1 0.4 0.066 13.6 0.4 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KER18247.1 - 0.065 13.0 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KER18247.1 - 0.069 13.5 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KER18247.1 - 0.081 11.8 0.1 0.091 11.7 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KER18247.1 - 0.15 12.3 0.5 0.22 11.8 0.4 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KER18247.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KER18247.1 - 0.23 11.7 0.1 0.39 10.9 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Phage_30_3 PF08010.11 KER18248.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Amidase PF01425.21 KER18251.1 - 1.6e-27 96.6 0.3 2.6e-27 95.9 0.0 1.5 2 0 0 2 2 2 1 Amidase DUF3512 PF12024.8 KER18255.1 - 0.041 13.4 0.1 0.053 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) HD_3 PF13023.6 KER18255.1 - 0.062 13.2 0.4 0.13 12.2 0.1 1.6 1 1 1 2 2 2 0 HD domain Pkinase PF00069.25 KER18260.1 - 2.3e-14 53.4 0.0 2.5e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18260.1 - 3.1e-06 26.7 0.0 3.1e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3H2C3 PF17122.5 KER18260.1 - 0.015 15.3 0.4 0.02 15.0 0.4 1.2 1 0 0 1 1 1 0 Zinc-finger Haspin_kinase PF12330.8 KER18260.1 - 0.046 12.7 0.0 0.048 12.6 0.0 1.0 1 0 0 1 1 1 0 Haspin like kinase domain I-set PF07679.16 KER18262.1 - 1.5e-10 41.0 0.0 6e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER18262.1 - 8.1e-07 29.5 0.0 1.2e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER18262.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 Immunoglobulin V-set domain SpoVT_C PF15714.5 KER18265.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor PG_binding_3 PF09374.10 KER18266.1 - 0.032 14.5 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Peptidoglycan domain DUF4315 PF14193.6 KER18266.1 - 0.12 12.5 0.9 0.14 12.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF4859 PF16151.5 KER18266.1 - 0.17 11.7 0.1 0.2 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Sec1 PF00995.23 KER18267.1 - 7e-10 38.8 0.0 7e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3512 PF12024.8 KER18270.1 - 0.0008 19.0 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) SpoVT_C PF15714.5 KER18270.1 - 0.068 13.2 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor PDZ PF00595.24 KER18271.1 - 2.3e-10 40.7 0.2 1.2e-09 38.4 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KER18271.1 - 1.6e-06 27.9 0.5 2.8e-06 27.1 0.5 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER18271.1 - 0.00028 21.1 0.1 0.00038 20.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain CTP_transf_1 PF01148.20 KER18274.1 - 3.2e-23 82.8 0.8 3.2e-23 82.8 0.8 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Paf67 PF10255.9 KER18275.1 - 2e-30 106.1 0.5 2.1e-30 106.0 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 EAF PF09816.9 KER18277.1 - 5.4e-13 49.2 0.0 5.9e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor RGCC PF15151.6 KER18278.1 - 0.066 13.4 5.7 0.089 13.0 5.7 1.4 1 1 0 1 1 1 0 Response gene to complement 32 protein family YopE_N PF09020.10 KER18280.1 - 0.073 13.3 0.1 0.089 13.0 0.1 1.2 1 0 0 1 1 1 0 YopE, N terminal CUB PF00431.20 KER18281.1 - 0.0056 17.0 0.0 0.0077 16.6 0.0 1.2 1 0 0 1 1 1 1 CUB domain Parvo_NS1 PF01057.17 KER18282.1 - 3.2e-07 29.7 0.0 3.8e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18282.1 - 0.056 12.3 0.0 0.058 12.2 0.0 1.0 1 0 0 1 1 1 0 Papillomavirus helicase CdhD PF03599.16 KER18282.1 - 0.096 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Ig_3 PF13927.6 KER18285.1 - 0.00044 20.8 0.0 0.00053 20.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER18285.1 - 0.00053 20.0 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain DDRGK PF09756.9 KER18286.1 - 9.3e-05 22.1 23.6 9.3e-05 22.1 23.6 1.4 2 0 0 2 2 2 1 DDRGK domain eIF3_subunit PF08597.10 KER18286.1 - 0.44 10.4 24.6 0.5 10.2 24.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PPP4R2 PF09184.11 KER18286.1 - 2 7.9 12.5 2.5 7.6 12.5 1.0 1 0 0 1 1 1 0 PPP4R2 Cation_ATPase PF13246.6 KER18288.1 - 1.6e-07 31.3 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Peptidase_C1 PF00112.23 KER18289.1 - 2.6e-14 53.9 0.1 4.2e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER18289.1 - 3.4e-12 46.6 1.0 5.3e-12 46.0 1.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) SRCR PF00530.18 KER18290.1 - 0.051 14.1 0.1 0.064 13.8 0.1 1.2 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain E3_UbLigase_R4 PF13764.6 KER18291.1 - 0.019 13.2 0.0 0.019 13.1 0.0 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Peptidase_M50 PF02163.22 KER18292.1 - 5.7e-12 45.4 1.1 6.2e-12 45.3 1.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 Prp19 PF08606.11 KER18294.1 - 3.7e-28 97.3 2.1 3.8e-28 97.3 1.2 1.4 2 0 0 2 2 2 1 Prp19/Pso4-like U-box PF04564.15 KER18294.1 - 2.5e-09 37.2 0.1 5.9e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KER18294.1 - 1.5e-06 27.9 0.1 3.8e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Cep57_MT_bd PF06657.13 KER18294.1 - 0.019 15.4 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CEBP_ZZ PF16366.5 KER18295.1 - 0.012 15.9 4.9 0.012 15.9 4.9 2.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-B_box PF00643.24 KER18295.1 - 0.016 15.4 7.2 0.016 15.4 7.2 3.1 3 1 0 3 3 3 0 B-box zinc finger IBR PF01485.21 KER18295.1 - 1 9.6 17.7 0.95 9.7 14.6 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain NIBRIN_BRCT_II PF16508.5 KER18298.1 - 0.084 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein Gar1 PF04410.14 KER18302.1 - 9.2e-25 87.2 0.0 1.1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Nucleoporin_C PF03177.14 KER18303.1 - 0.00031 19.6 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TPR_14 PF13428.6 KER18303.1 - 0.15 12.9 1.4 1.3 10.0 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1289 PF06945.13 KER18306.1 - 0.00036 20.3 0.2 0.00037 20.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) COLFI PF01410.18 KER18306.1 - 0.023 14.0 0.3 0.023 14.0 0.3 1.0 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain PHF12_MRG_bd PF16737.5 KER18308.1 - 0.033 13.9 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain Yippee-Mis18 PF03226.14 KER18309.1 - 3.5e-14 52.9 0.1 4.8e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 KER18309.1 - 0.0027 17.6 1.8 0.0033 17.3 0.4 1.9 1 1 1 2 2 2 1 Recombination endonuclease VII HNH_5 PF14279.6 KER18309.1 - 0.0047 16.8 0.1 0.097 12.5 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease SelR PF01641.18 KER18309.1 - 0.022 14.8 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 SelR domain RIG-I_C-RD PF11648.8 KER18309.1 - 0.027 14.7 0.5 0.068 13.4 0.3 1.7 1 1 1 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.7 KER18309.1 - 0.058 13.4 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon Parvo_NS1 PF01057.17 KER18311.1 - 1.5e-08 34.1 0.1 1.8e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18311.1 - 1.5e-06 27.3 0.0 1.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase AAA_7 PF12775.7 KER18311.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KER18311.1 - 0.033 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KER18311.1 - 0.038 13.1 0.1 0.1 11.6 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KER18311.1 - 0.072 13.1 0.2 0.19 11.8 0.1 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KER18311.1 - 0.076 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SpoVT_C PF15714.5 KER18311.1 - 0.091 12.8 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor DUF1725 PF08333.11 KER18315.1 - 0.041 13.6 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Pkinase PF00069.25 KER18323.1 - 3.5e-26 92.1 0.0 4.3e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18323.1 - 7.4e-19 68.0 0.0 8.9e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER18323.1 - 9.2e-06 25.1 0.3 1.5e-05 24.4 0.3 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER18323.1 - 2.7e-05 23.2 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER18323.1 - 0.00085 19.3 0.7 0.0011 18.9 0.7 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER18323.1 - 0.0061 15.9 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER18323.1 - 0.044 12.7 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CI-B14_5a PF07347.12 KER18324.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Cystatin PF00031.21 KER18329.1 - 1.6e-07 31.5 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Tautomerase PF01361.21 KER18329.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Tautomerase_2 PF14552.6 KER18329.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Tautomerase enzyme fn3 PF00041.21 KER18332.1 - 1.2e-13 51.2 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain Lactamase_B PF00753.27 KER18334.1 - 2.3e-10 40.8 5.1 1.4e-09 38.3 5.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KER18334.1 - 0.015 14.8 0.3 0.026 14.0 0.3 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Shisa PF13908.6 KER18339.1 - 0.00093 19.5 1.8 0.00093 19.5 1.8 1.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator YgaB PF14182.6 KER18339.1 - 0.047 14.1 0.0 0.17 12.3 0.0 1.8 1 1 1 2 2 2 0 YgaB-like protein Phosphorylase PF00343.20 KER18340.1 - 1.3e-32 113.0 0.3 1.4e-32 112.9 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase COesterase PF00135.28 KER18341.1 - 0.0021 17.0 0.0 0.49 9.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family CSG2 PF16965.5 KER18343.1 - 0.14 11.1 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Asp PF00026.23 KER18345.1 - 2.7e-19 69.8 0.0 3.1e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER18345.1 - 2.4e-07 30.7 0.1 2.9e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Aldedh PF00171.22 KER18348.1 - 4.4e-12 45.2 0.0 4.7e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF433 PF04255.14 KER18348.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) RHH_1 PF01402.21 KER18348.1 - 0.14 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Beta_lactamase3 PF17030.5 KER18348.1 - 0.19 10.9 0.0 0.2 10.9 0.0 1.0 1 0 0 1 1 1 0 Putative beta-lactamase-like family MLVIN_C PF18697.1 KER18350.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Glyco_hydro_38N PF01074.22 KER18351.1 - 5e-56 190.2 0.1 5.7e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Orthoreo_P17 PF07272.11 KER18351.1 - 0.086 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Orthoreovirus P17 protein ASH PF15780.5 KER18352.1 - 0.024 14.8 0.3 0.11 12.7 0.3 1.9 1 1 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GKAP PF03359.13 KER18353.1 - 4.9e-26 92.1 0.2 7.3e-26 91.6 0.2 1.3 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein AAA_7 PF12775.7 KER18354.1 - 2.4e-56 190.1 0.0 2.7e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 P-loop containing dynein motor region SDF PF00375.18 KER18355.1 - 6.2e-06 25.5 0.1 6.2e-06 25.5 0.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family ECH_2 PF16113.5 KER18356.1 - 4.8e-28 98.6 0.2 5.2e-28 98.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KER18356.1 - 8.5e-07 28.5 0.1 9.6e-07 28.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase EMP24_GP25L PF01105.24 KER18357.1 - 9.4e-21 74.6 0.1 1.1e-20 74.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Stealth_CR4 PF17103.5 KER18357.1 - 0.073 13.0 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 SQS_PSY PF00494.19 KER18359.1 - 1.3e-13 51.1 0.0 1.5e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_M13 PF01431.21 KER18360.1 - 0.00078 19.1 0.1 0.001 18.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 FXR_C1 PF16096.5 KER18361.1 - 3.5 7.9 8.6 3.1 8.1 6.7 2.1 2 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Asp PF00026.23 KER18364.1 - 1.2e-15 57.8 0.2 1.4e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER18364.1 - 8e-06 26.2 0.4 0.011 16.0 0.1 2.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER18364.1 - 0.0051 17.4 0.0 0.023 15.4 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KER18364.1 - 0.018 15.6 0.0 0.049 14.2 0.0 1.7 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4521 PF15021.6 KER18364.1 - 0.049 13.5 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) HEAT_EZ PF13513.6 KER18367.1 - 0.0095 16.4 5.3 0.067 13.7 0.1 3.7 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KER18367.1 - 5.8 7.5 10.9 2.1 8.8 0.2 3.6 5 0 0 5 5 5 0 HEAT repeat Lon_C PF05362.13 KER18370.1 - 4e-08 33.0 0.0 4.8e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DUF846 PF05832.12 KER18372.1 - 2.9e-18 66.3 0.0 4.1e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) RHSP PF07999.11 KER18375.1 - 0.063 12.1 0.1 0.069 12.0 0.1 1.0 1 0 0 1 1 1 0 Retrotransposon hot spot protein ESPR PF13018.6 KER18375.1 - 0.19 11.5 1.2 0.19 11.5 1.2 1.9 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system ZU5 PF00791.20 KER18376.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 ZU5 domain PK PF00224.21 KER18381.1 - 3.8e-23 81.9 0.1 4e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain BACK PF07707.15 KER18382.1 - 9.6e-16 57.8 3.2 4.6e-15 55.6 1.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KER18382.1 - 0.00071 19.8 2.2 0.0033 17.7 0.1 2.6 2 1 1 3 3 3 1 BTB/POZ domain ABC_membrane PF00664.23 KER18383.1 - 3.3e-20 72.9 0.0 4.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region FixQ PF05545.11 KER18383.1 - 0.066 13.2 0.1 0.53 10.3 0.0 2.4 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4349 PF14257.6 KER18383.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SecY PF00344.20 KER18384.1 - 2.6e-29 102.5 5.9 4.4e-29 101.7 5.9 1.3 1 1 0 1 1 1 1 SecY translocase Tricorn_C1 PF14684.6 KER18385.1 - 0.028 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Tricorn protease C1 domain DSHCT PF08148.12 KER18389.1 - 1.2e-10 41.3 0.0 1.3e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 DSHCT (NUC185) domain DUF2845 PF11006.8 KER18392.1 - 0.088 12.9 0.3 0.11 12.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2845) ELO PF01151.18 KER18396.1 - 6.5e-35 120.9 1.1 7.3e-35 120.7 1.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GTP_EFTU_D3 PF03143.17 KER18398.1 - 1.6e-08 34.9 0.1 1.6e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain AMP-binding PF00501.28 KER18400.1 - 4.1e-09 35.5 0.0 4.6e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PYC_OADA PF02436.18 KER18404.1 - 4.7e-09 36.3 0.0 5e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Conserved carboxylase domain WD40_3 PF15911.5 KER18405.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat FAP206 PF12018.8 KER18406.1 - 5.5e-14 52.3 0.0 5.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function CdvA PF18822.1 KER18406.1 - 0.074 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Chromo PF00385.24 KER18409.1 - 8.5e-10 38.4 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain hSH3 PF14603.6 KER18409.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Glyco_hydro_15 PF00723.21 KER18410.1 - 0.041 12.7 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Phosphorylase PF00343.20 KER18413.1 - 3.1e-43 148.1 0.0 3.4e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Peptidase_M41 PF01434.18 KER18419.1 - 1.8e-19 70.4 0.0 1.9e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M41 BAR PF03114.18 KER18423.1 - 1.1e-05 25.2 0.1 1.2e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 BAR domain Ribosomal_L29 PF00831.23 KER18423.1 - 0.025 14.5 2.4 0.056 13.4 2.4 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein CM_2 PF01817.21 KER18423.1 - 0.041 14.2 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 Chorismate mutase type II MIP PF00230.20 KER18430.1 - 1e-29 103.9 6.7 1.2e-29 103.6 6.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S8 PF00082.22 KER18431.1 - 0.0031 16.8 0.0 0.005 16.1 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PWWP PF00855.17 KER18433.1 - 1.4e-12 47.8 0.2 1.9e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 PWWP domain STI1 PF17830.1 KER18433.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 STI1 domain Kisspeptin PF15152.6 KER18435.1 - 4.9 8.0 10.6 0.58 11.0 2.5 2.1 1 1 1 2 2 2 0 Kisspeptin 7tm_1 PF00001.21 KER18437.1 - 5.8e-18 65.2 6.7 7.1e-18 64.9 6.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Claudin_2 PF13903.6 KER18437.1 - 0.011 15.5 7.8 0.084 12.6 4.3 2.8 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction TMEM154 PF15102.6 KER18437.1 - 0.054 13.4 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF2633 PF11119.8 KER18437.1 - 0.087 12.7 0.7 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) CMV_US PF08001.11 KER18443.1 - 0.08 12.2 0.1 0.09 12.0 0.1 1.1 1 0 0 1 1 1 0 CMV US UQ_con PF00179.26 KER18444.1 - 1.2e-50 170.8 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER18444.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER18444.1 - 0.022 15.0 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Parvo_NS1 PF01057.17 KER18445.1 - 1.7e-10 40.5 0.1 0.00012 21.3 0.0 2.2 1 1 1 2 2 2 2 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18445.1 - 0.00012 21.1 0.1 0.079 11.8 0.0 2.2 2 0 0 2 2 2 2 Papillomavirus helicase T2SSE PF00437.20 KER18445.1 - 0.00082 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KER18445.1 - 0.0026 17.3 0.1 0.0067 16.0 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region SurA_N PF09312.11 KER18445.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain DUF3549 PF12069.8 KER18445.1 - 0.097 11.7 0.2 0.97 8.4 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3549) AAA_14 PF13173.6 KER18445.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SpoVT_C PF15714.5 KER18445.1 - 0.11 12.6 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor AAA PF00004.29 KER18445.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.26 KER18446.1 - 5.4e-14 51.8 24.0 0.00017 21.9 3.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER18446.1 - 3.9e-09 36.6 25.1 0.0018 18.9 3.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER18446.1 - 0.0025 18.1 18.0 0.016 15.6 4.1 4.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-BED PF02892.15 KER18446.1 - 0.0033 17.4 14.4 1.6 8.8 3.0 3.6 4 0 0 4 4 3 3 BED zinc finger zf-C2H2_2 PF12756.7 KER18446.1 - 0.0047 17.2 13.7 0.041 14.2 0.8 3.1 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KER18446.1 - 0.0051 16.7 2.0 0.0051 16.7 2.0 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 KER18446.1 - 0.0053 17.1 12.1 0.011 16.1 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CpXC PF14353.6 KER18446.1 - 0.0064 16.5 4.2 0.18 11.8 1.4 2.8 1 1 1 2 2 2 1 CpXC protein zf-C2H2_6 PF13912.6 KER18446.1 - 0.0074 16.3 16.9 0.02 14.9 4.1 3.0 3 1 0 3 3 3 2 C2H2-type zinc finger PyrI_C PF02748.15 KER18446.1 - 0.022 14.6 5.2 0.12 12.3 0.2 3.1 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 KER18446.1 - 0.026 15.3 4.1 0.11 13.3 3.3 2.1 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KER18446.1 - 0.03 14.6 12.3 0.92 9.9 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KER18446.1 - 0.046 13.7 6.9 0.86 9.6 0.6 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_3 PF13878.6 KER18446.1 - 0.047 13.5 3.7 9.4 6.2 0.0 3.6 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.5 KER18446.1 - 0.094 12.5 20.8 0.5 10.2 1.6 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type CxC7 PF18866.1 KER18446.1 - 0.11 12.6 2.2 2.4 8.3 0.1 2.8 2 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases zf-CHCC PF10276.9 KER18446.1 - 0.13 12.3 5.2 2.7 8.1 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger domain HNH PF01844.23 KER18446.1 - 0.25 11.5 5.8 1.6 9.0 1.3 3.0 2 1 1 3 3 3 0 HNH endonuclease zf-Di19 PF05605.12 KER18446.1 - 0.44 10.9 10.9 3.8 7.9 0.5 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Mut7-C PF01927.16 KER18446.1 - 0.5 10.5 6.8 0.096 12.8 1.9 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain C1_2 PF03107.16 KER18446.1 - 0.52 10.7 8.8 13 6.2 0.2 3.5 1 1 2 3 3 3 0 C1 domain zf-RING_7 PF02591.15 KER18446.1 - 9.6 6.5 11.7 2.2 8.5 0.2 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain LodA_N PF17990.1 KER18448.1 - 0.053 13.4 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal Usp PF00582.26 KER18449.1 - 3.4e-05 24.4 0.0 3.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 KER18452.1 - 0.0023 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain COesterase PF00135.28 KER18454.1 - 1.2e-23 83.8 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Parvo_NS1 PF01057.17 KER18455.1 - 2.6e-11 43.1 0.0 3.1e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18455.1 - 2.4e-09 36.6 0.0 2.8e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.6 KER18455.1 - 0.023 14.7 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KER18455.1 - 0.031 14.7 0.1 0.074 13.5 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KER18455.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 KER18455.1 - 0.12 12.4 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AvrL567-A PF11529.8 KER18455.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A Peptidase_C1 PF00112.23 KER18456.1 - 9.3e-22 78.2 0.0 1e-21 78.1 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease V-set PF07686.17 KER18457.1 - 0.0052 16.9 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KER18457.1 - 0.033 14.4 0.0 0.09 13.0 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain Izumo-Ig PF16706.5 KER18457.1 - 0.035 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_2 PF13895.6 KER18457.1 - 0.057 13.8 0.1 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KER18457.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KER18457.1 - 0.14 12.7 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain EMP24_GP25L PF01105.24 KER18458.1 - 7.5e-09 35.8 0.0 8.1e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF930 PF06059.12 KER18460.1 - 0.018 15.6 0.1 0.046 14.3 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) Ig_3 PF13927.6 KER18460.1 - 0.12 13.0 2.1 2.5 8.7 0.4 3.3 2 2 0 2 2 2 0 Immunoglobulin domain DUF4590 PF15257.6 KER18461.1 - 0.0076 16.2 0.0 0.0092 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) Pkinase PF00069.25 KER18464.1 - 1.2e-33 116.7 0.5 1.3e-33 116.5 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18464.1 - 9.5e-23 80.8 0.1 1.2e-22 80.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KER18464.1 - 0.002 17.8 0.2 0.0039 16.8 0.2 1.8 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KER18464.1 - 0.0038 16.6 0.3 0.0085 15.5 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 KER18465.1 - 3.7e-08 33.7 0.1 0.0089 16.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER18465.1 - 1.4e-06 28.8 0.3 0.0027 18.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER18465.1 - 1.3e-05 25.2 0.2 0.081 13.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KER18465.1 - 2.1e-05 24.7 0.3 0.0043 17.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KER18465.1 - 0.023 15.1 0.4 3.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat zf-B_box PF00643.24 KER18467.1 - 8.7e-06 25.8 2.5 1.4e-05 25.1 2.5 1.3 1 0 0 1 1 1 1 B-box zinc finger MICSWaP PF17018.5 KER18467.1 - 0.069 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Spore wall protein BicD PF09730.9 KER18468.1 - 1.2e-10 40.5 13.5 2.2e-10 39.6 13.5 1.4 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D MscS_porin PF12795.7 KER18468.1 - 0.00011 21.8 11.3 0.016 14.8 1.9 2.1 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain APG6_N PF17675.1 KER18468.1 - 0.00038 21.0 14.6 0.003 18.1 3.1 2.4 2 0 0 2 2 2 2 Apg6 coiled-coil region Gag_p17 PF00540.18 KER18468.1 - 0.002 18.1 0.6 0.0063 16.5 0.0 2.0 2 0 0 2 2 2 1 gag gene protein p17 (matrix protein) LMBR1 PF04791.16 KER18468.1 - 0.0022 17.0 2.0 0.0028 16.6 2.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 KER18468.1 - 0.0025 17.8 1.1 0.1 12.6 0.1 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.6 KER18468.1 - 0.0032 17.1 10.0 0.12 11.9 1.1 2.1 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 3 DUF4763 PF15960.5 KER18468.1 - 0.0076 15.6 1.1 0.0076 15.6 1.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4763) Spc7 PF08317.11 KER18468.1 - 0.013 14.4 11.0 0.3 9.9 2.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FmiP_Thoc5 PF09766.9 KER18468.1 - 0.016 14.5 1.0 0.016 14.5 1.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Macoilin PF09726.9 KER18468.1 - 0.016 13.8 0.3 0.016 13.8 0.3 1.9 2 0 0 2 2 2 0 Macoilin family DUF641 PF04859.12 KER18468.1 - 0.026 14.9 8.2 0.83 10.0 1.0 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 KER18468.1 - 0.037 13.3 7.9 0.54 9.4 1.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KER18468.1 - 0.045 13.9 10.6 0.055 13.7 2.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 KER18468.1 - 0.048 13.3 9.8 0.14 11.8 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Fez1 PF06818.15 KER18468.1 - 0.05 14.1 11.2 0.53 10.7 0.5 2.2 2 0 0 2 2 2 0 Fez1 Vps52 PF04129.12 KER18468.1 - 0.059 12.1 3.3 0.5 9.0 0.1 2.1 2 0 0 2 2 2 0 Vps52 / Sac2 family ADIP PF11559.8 KER18468.1 - 0.089 12.9 12.4 0.25 11.4 0.5 2.5 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 KER18468.1 - 0.091 11.4 12.2 0.21 10.2 2.7 2.1 1 1 1 2 2 2 0 AAA domain CEP63 PF17045.5 KER18468.1 - 0.096 12.6 12.3 0.11 12.4 0.9 2.5 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa Fungal_TACC PF12709.7 KER18468.1 - 0.15 12.5 11.5 0.29 11.6 1.1 3.0 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins HemX PF04375.14 KER18468.1 - 0.26 10.5 14.3 0.57 9.4 3.3 2.2 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATG16 PF08614.11 KER18468.1 - 0.36 11.0 21.1 0.12 12.6 7.4 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) UME PF08064.13 KER18468.1 - 0.37 10.7 2.1 6 6.8 0.4 3.0 2 1 2 4 4 4 0 UME (NUC010) domain DUF3450 PF11932.8 KER18468.1 - 0.38 10.0 12.8 0.76 9.0 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KER18468.1 - 0.43 10.6 8.8 0.75 9.8 0.8 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KER18468.1 - 0.43 10.6 16.6 2 8.4 1.4 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4988 PF16378.5 KER18468.1 - 0.44 10.2 2.8 8.2 6.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function zf-CpG_bind_C PF12269.8 KER18468.1 - 0.46 10.2 6.4 0.91 9.3 0.8 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain TPR_MLP1_2 PF07926.12 KER18468.1 - 0.72 9.9 14.5 3.9 7.5 6.0 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CEP209_CC5 PF16574.5 KER18468.1 - 0.76 10.0 11.9 0.13 12.4 1.7 2.5 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 RP-C PF03428.13 KER18468.1 - 0.86 9.2 7.6 0.17 11.5 0.4 2.7 3 0 0 3 3 3 0 Replication protein C N-terminal domain HrpB7 PF09486.10 KER18468.1 - 1.3 9.3 14.9 0.74 10.2 1.5 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Cnn_1N PF07989.11 KER18468.1 - 1.8 8.8 12.8 5.3 7.3 0.9 3.2 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KER18468.1 - 2 8.7 18.9 2.6 8.4 6.1 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 KER18468.1 - 2.4 8.6 8.3 9.1 6.8 1.0 3.1 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KER18468.1 - 3 8.0 9.8 5.4 7.1 2.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 KER18468.1 - 3.9 8.0 23.0 0.057 13.9 6.0 3.0 3 1 0 3 3 2 0 Cell division protein ZapB SseC PF04888.12 KER18468.1 - 4.1 6.9 10.0 7.5 6.0 3.1 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF4200 PF13863.6 KER18468.1 - 5.7 7.4 17.8 0.45 10.9 2.7 3.1 3 1 0 3 3 2 0 Domain of unknown function (DUF4200) Med9 PF07544.13 KER18468.1 - 5.7 7.1 9.3 12 6.0 0.8 3.0 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 HIP1_clath_bdg PF16515.5 KER18468.1 - 8.4 7.1 18.9 2.1 9.0 4.0 2.8 2 2 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 KER18468.1 - 8.4 6.2 13.8 0.87 9.4 3.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CorA PF01544.18 KER18468.1 - 8.5 5.6 8.3 2.3 7.5 0.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 KER18468.1 - 9 7.0 12.7 2.5 8.8 0.4 3.5 3 1 1 4 4 3 0 SlyX CTV_P6 PF06706.11 KER18469.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Glycoprot_B_PH2 PF17417.2 KER18470.1 - 0.21 12.0 0.9 0.29 11.5 0.7 1.4 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain DUF4467 PF14729.6 KER18473.1 - 0.032 14.6 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) DUF3203 PF11462.8 KER18473.1 - 0.042 14.0 0.4 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) MFS_1 PF07690.16 KER18474.1 - 4.1e-07 29.3 15.2 4.1e-07 29.3 15.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 KER18474.1 - 0.0083 16.2 0.0 0.0083 16.2 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF4229) Wzz PF02706.15 KER18474.1 - 1.2 9.5 3.6 6.5 7.1 0.5 2.7 3 0 0 3 3 3 0 Chain length determinant protein DUF2371 PF10177.9 KER18474.1 - 1.2 9.3 3.7 3.2 7.9 0.0 2.8 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) ASC PF00858.24 KER18479.1 - 5.2e-16 58.7 0.6 5.9e-16 58.5 0.6 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel adh_short PF00106.25 KER18480.1 - 4.4e-17 62.2 0.0 5e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER18480.1 - 1.2e-07 31.5 0.0 1.4e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KER18480.1 - 0.036 13.4 0.2 0.041 13.3 0.2 1.0 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PLAT PF01477.23 KER18481.1 - 2.6e-20 73.2 0.1 6e-17 62.3 0.0 2.4 2 1 0 2 2 2 2 PLAT/LH2 domain Usp PF00582.26 KER18482.1 - 3e-29 102.3 0.0 3.4e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family YojJ PF10372.9 KER18483.1 - 0.0031 17.6 0.6 0.34 11.0 0.0 2.4 1 1 1 2 2 2 2 Bacterial membrane-spanning protein N-terminus DUF4763 PF15960.5 KER18483.1 - 0.031 13.6 3.8 0.036 13.4 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) FlaC_arch PF05377.11 KER18483.1 - 0.083 13.3 0.8 0.55 10.7 0.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KER18483.1 - 0.17 12.3 3.9 0.12 12.7 1.2 2.1 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bcr-Abl_Oligo PF09036.10 KER18483.1 - 0.35 10.9 2.3 0.27 11.2 0.5 1.8 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4140 PF13600.6 KER18483.1 - 1.4 9.4 4.7 2.1 8.9 2.2 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_tail_APC PF16778.5 KER18483.1 - 3.5 7.6 5.5 1.7 8.6 2.2 2.1 2 1 0 2 2 2 0 Phage tail assembly chaperone protein Asp PF00026.23 KER18484.1 - 0.00094 18.7 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Helicase_C PF00271.31 KER18485.1 - 1.3e-07 31.9 0.0 1.3e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KER18485.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Adaptin_N PF01602.20 KER18488.1 - 4.2e-11 42.1 0.1 4.5e-11 42.0 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region AdoHcyase PF05221.17 KER18489.1 - 9.8e-79 264.6 0.0 1e-57 195.6 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KER18489.1 - 1.3e-31 109.9 0.5 2.3e-31 109.0 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 KER18489.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Cyclin_N PF00134.23 KER18490.1 - 1e-06 28.5 0.3 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KER18490.1 - 0.0019 18.2 0.8 0.42 10.7 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TSP_1 PF00090.19 KER18491.1 - 8.9e-05 22.6 9.7 0.0002 21.5 9.7 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain Fz PF01392.22 KER18492.1 - 4.3e-31 107.8 2.3 6.9e-31 107.1 2.3 1.3 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 KER18492.1 - 5.2e-26 91.5 1.4 7.6e-26 90.9 1.4 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region WD40 PF00400.32 KER18495.1 - 3e-08 34.2 0.1 3.6e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER18495.1 - 0.00014 22.1 0.0 0.00022 21.4 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KER18495.1 - 0.0026 17.7 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF397 PF04149.12 KER18495.1 - 0.062 13.4 0.6 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF397) TFIIIC_delta PF12657.7 KER18495.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term RAD51_interact PF15696.5 KER18498.1 - 1.4e-07 31.5 1.0 3.6e-07 30.2 1.0 1.8 1 0 0 1 1 1 1 RAD51 interacting motif DUF2718 PF10918.8 KER18498.1 - 0.77 10.3 3.6 1 9.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) LicD PF04991.13 KER18499.1 - 0.0019 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 LicD family rRNA_proc-arch PF13234.6 KER18500.1 - 4.5e-14 53.0 0.0 4.9e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 rRNA-processing arch domain Rootletin PF15035.6 KER18505.1 - 0.00021 21.4 5.1 0.00028 21.0 5.1 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Ntox1 PF15500.6 KER18505.1 - 0.016 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 FAM110_C PF14160.6 KER18505.1 - 0.019 16.1 0.0 0.023 15.8 0.0 1.2 1 0 0 1 1 1 0 Centrosome-associated C terminus Homeobox_KN PF05920.11 KER18509.1 - 0.0003 20.6 1.8 0.00035 20.4 0.4 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KER18509.1 - 0.024 14.5 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Homeodomain PGA2 PF07543.12 KER18509.1 - 0.069 13.1 0.7 0.069 13.1 0.7 2.0 1 1 1 2 2 2 0 Protein trafficking PGA2 RasGEF_N PF00618.20 KER18510.1 - 0.052 13.8 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 RasGEF N-terminal motif Spc7 PF08317.11 KER18512.1 - 0.0012 17.9 7.3 0.0015 17.4 7.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KER18512.1 - 0.008 16.3 9.6 0.008 16.3 9.6 2.2 2 1 0 2 2 2 1 Tropomyosin like bZIP_2 PF07716.15 KER18512.1 - 0.0094 16.0 15.1 1.1 9.4 0.2 4.2 4 0 0 4 4 4 2 Basic region leucine zipper YabA PF06156.13 KER18512.1 - 0.013 16.1 9.1 0.13 13.0 4.2 2.6 2 2 0 2 2 2 0 Initiation control protein YabA TMCO5 PF14992.6 KER18512.1 - 0.04 13.5 6.2 0.067 12.8 6.2 1.4 1 0 0 1 1 1 0 TMCO5 family GOLGA2L5 PF15070.6 KER18512.1 - 0.063 11.9 9.8 0.17 10.5 9.8 1.6 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Exonuc_VII_L PF02601.15 KER18512.1 - 0.12 12.0 6.0 0.14 11.7 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Yuri_gagarin PF15934.5 KER18512.1 - 0.12 12.2 7.2 0.072 12.9 4.5 1.9 1 1 1 2 2 2 0 Yuri gagarin CCDC-167 PF15188.6 KER18512.1 - 0.56 10.6 17.6 0.5 10.7 3.4 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 NRBF2 PF08961.10 KER18512.1 - 0.77 9.3 16.6 0.21 11.2 5.9 3.0 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 KER18512.1 - 0.85 9.9 10.0 17 5.7 0.1 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF2353 PF09789.9 KER18512.1 - 1.6 8.1 15.0 2.3 7.5 12.4 1.8 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) FapA PF03961.13 KER18512.1 - 2.5 6.6 6.8 2 6.9 5.4 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Uds1 PF15456.6 KER18512.1 - 3.6 7.8 13.1 2.1 8.5 9.2 2.2 1 1 1 2 2 2 0 Up-regulated During Septation DUF4201 PF13870.6 KER18512.1 - 3.8 7.2 15.6 18 5.0 11.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ADIP PF11559.8 KER18512.1 - 8.1 6.5 16.1 1.7 8.7 7.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 KER18512.1 - 9.2 6.5 14.0 7.5 6.8 1.6 4.1 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II zf-C2H2_4 PF13894.6 KER18513.1 - 8.7e-06 26.2 41.5 0.087 13.7 3.9 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KER18513.1 - 8.9e-06 25.9 42.9 0.17 12.4 7.1 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KER18513.1 - 0.0057 17.3 7.6 0.0057 17.3 7.6 2.4 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KER18513.1 - 0.012 16.1 4.3 0.012 16.1 4.3 6.5 6 2 0 6 6 6 0 Zinc-finger double domain Lipase_bact_N PF12262.8 KER18513.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal zf-C2H2_jaz PF12171.8 KER18513.1 - 0.2 12.0 29.1 0.15 12.3 3.6 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER18513.1 - 0.24 11.8 24.9 2.3 8.7 0.4 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Serpin PF00079.20 KER18515.1 - 2.6e-12 46.8 0.0 2.9e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KER18516.1 - 6.3e-12 45.5 0.1 7.2e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) fn3 PF00041.21 KER18525.1 - 2.6e-12 46.9 0.1 4.3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Dioxygenase_C PF00775.21 KER18525.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase HSA PF07529.13 KER18527.1 - 3e-16 59.5 13.9 3e-16 59.5 13.9 3.5 3 0 0 3 3 3 1 HSA BRK PF07533.16 KER18527.1 - 7.1e-12 44.8 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 BRK domain BTV_NS2 PF04514.12 KER18527.1 - 0.048 12.5 3.1 0.069 12.0 3.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NCOA_u2 PF16665.5 KER18527.1 - 0.75 10.1 3.0 1.6 9.0 3.0 1.5 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein PWI PF01480.17 KER18529.1 - 7.4e-06 26.2 0.1 1.2e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 PWI domain DUF4422 PF14393.6 KER18529.1 - 0.015 15.1 0.1 0.035 14.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) CEP76-C2 PF15627.6 KER18529.1 - 0.084 12.4 0.7 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 CEP76 C2 domain Glutaredoxin PF00462.24 KER18530.1 - 0.14 12.4 0.2 3.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Glutaredoxin adh_short PF00106.25 KER18531.1 - 1.2e-13 51.0 0.1 1.3e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER18531.1 - 2.6e-06 27.5 0.1 3.4e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KER18531.1 - 6.6e-05 22.6 0.1 7.6e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KER18531.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KER18531.1 - 0.0058 17.2 0.0 0.0076 16.8 0.0 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KER18531.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 KER18531.1 - 0.048 13.0 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KER18531.1 - 0.072 12.7 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KER18531.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KER18531.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KER18531.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 KER18534.1 - 3.8e-07 29.7 0.0 4.4e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18534.1 - 0.0011 18.3 0.0 0.0011 18.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Dymeclin PF09742.9 KER18535.1 - 9.5e-33 113.5 0.1 1e-32 113.4 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KER18535.1 - 1.8e-29 102.5 0.4 2e-29 102.4 0.4 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Peptidase_C13 PF01650.18 KER18537.1 - 5.9e-17 62.0 0.4 7.1e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C1 PF00112.23 KER18538.1 - 1.2e-34 120.3 0.0 1.7e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER18538.1 - 1.6e-11 44.5 1.2 2.5e-11 43.8 1.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) adh_short PF00106.25 KER18539.1 - 1.3e-12 47.5 0.0 1.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER18539.1 - 0.00011 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KER18539.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KER18539.1 - 0.0047 17.2 0.0 0.0065 16.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KER18539.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KER18539.1 - 0.03 13.5 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KER18539.1 - 0.21 11.5 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChaC PF04752.12 KER18543.1 - 1.6e-11 44.6 0.0 1.6e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein zinc_ribbon_16 PF17034.5 KER18546.1 - 1.6e-07 31.6 0.3 2.9e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-ribbon like family zf-RING_5 PF14634.6 KER18546.1 - 0.09 12.8 1.4 0.09 12.8 1.4 1.6 2 0 0 2 2 2 0 zinc-RING finger domain APO_RNA-bind PF05634.11 KER18547.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 APO RNA-binding TMF_TATA_bd PF12325.8 KER18548.1 - 5.6e-29 100.7 3.1 6.2e-29 100.6 3.1 1.0 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 KER18548.1 - 4.8e-06 26.7 4.4 0.014 15.6 0.6 2.2 2 0 0 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.15 KER18548.1 - 0.028 14.2 1.2 0.055 13.2 0.1 1.9 2 1 0 2 2 2 0 Septum formation initiator DUF3293 PF11697.8 KER18548.1 - 0.061 13.8 0.2 0.16 12.5 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3293) ZapB PF06005.12 KER18548.1 - 0.16 12.5 3.9 1.6 9.3 0.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB PP28 PF10252.9 KER18548.1 - 0.17 12.3 0.5 0.17 12.3 0.5 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 bZIP_1 PF00170.21 KER18548.1 - 0.37 10.9 6.0 2.7 8.1 0.3 2.4 2 1 0 2 2 2 0 bZIP transcription factor YdjM PF04307.14 KER18549.1 - 0.06 12.7 0.6 0.077 12.3 0.6 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Parvo_NS1 PF01057.17 KER18551.1 - 2.1e-14 53.3 0.3 3.5e-14 52.6 0.2 1.3 1 1 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18551.1 - 8.1e-10 38.1 0.0 1.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase AAA_7 PF12775.7 KER18551.1 - 0.019 14.5 0.2 0.046 13.2 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SpoVT_C PF15714.5 KER18551.1 - 0.024 14.7 0.0 0.073 13.1 0.0 1.8 1 1 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor AAA_14 PF13173.6 KER18551.1 - 0.03 14.4 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KER18551.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KER18551.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UCR_Fe-S_N PF10399.9 KER18552.1 - 0.11 11.9 3.2 0.2 11.0 3.2 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ig PF00047.25 KER18553.1 - 0.11 12.7 0.3 22 5.3 0.0 2.6 2 1 0 2 2 2 0 Immunoglobulin domain Spo12 PF05032.12 KER18553.1 - 0.11 12.5 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Spo12 family V-set PF07686.17 KER18553.1 - 0.11 12.7 0.0 0.33 11.1 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_3 PF13927.6 KER18553.1 - 0.15 12.7 0.7 2.4 8.8 0.1 2.7 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KER18553.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain ARPC4 PF05856.12 KER18555.1 - 1.2e-49 168.1 1.6 1.4e-49 168.0 1.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 KER18555.1 - 0.0032 17.6 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Sm_like domain RPN1_C PF18051.1 KER18560.1 - 3.1e-30 104.0 0.1 4.8e-30 103.4 0.1 1.3 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal DUF758 PF05527.11 KER18561.1 - 2.4e-35 122.1 1.5 2.6e-35 122.0 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) BCDHK_Adom3 PF10436.9 KER18564.1 - 3e-41 141.0 0.8 3.5e-41 140.8 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DASH_Duo1 PF08651.10 KER18565.1 - 0.04 13.7 0.3 0.044 13.6 0.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 eIF3g PF12353.8 KER18567.1 - 1.4e-08 35.2 2.7 1.9e-08 34.8 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCCH_6 PF18585.1 KER18567.1 - 0.0056 16.5 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Fer4_20 PF14691.6 KER18567.1 - 0.023 14.4 0.5 0.024 14.4 0.5 1.1 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster AdoHcyase PF05221.17 KER18568.1 - 1.3e-12 47.5 0.0 1.4e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase ADK PF00406.22 KER18570.1 - 0.00015 21.9 0.0 0.00015 21.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase E1_dh PF00676.20 KER18571.1 - 1.2e-27 96.7 0.0 1.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component COX6B PF02297.17 KER18573.1 - 2.5e-11 43.6 4.8 2.5e-11 43.6 4.8 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb SPOC PF07744.13 KER18573.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 SPOC domain tRNA-synt_1c_C PF03950.18 KER18576.1 - 4.2e-15 56.1 0.0 4.6e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain UN_NPL4 PF11543.8 KER18576.1 - 0.082 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 MT PF12777.7 KER18577.1 - 1e-38 133.3 0.2 1.2e-38 133.1 0.2 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 KER18577.1 - 0.00039 19.6 0.9 0.0011 18.2 0.0 2.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Gon7 PF08738.10 KER18577.1 - 0.056 13.5 0.1 0.085 12.9 0.1 1.3 1 0 0 1 1 1 0 Gon7 family Arrestin_N PF00339.29 KER18579.1 - 8.7e-07 29.1 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF447 PF04289.12 KER18579.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF447) zf-C2H2 PF00096.26 KER18582.1 - 3.8e-15 55.4 22.7 5.6e-05 23.4 0.9 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER18582.1 - 2.3e-14 53.1 22.9 0.0001 22.6 1.0 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER18582.1 - 5e-13 48.7 21.3 0.0037 18.0 0.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KER18582.1 - 1.4e-08 35.4 12.4 0.016 15.9 0.1 4.1 1 1 3 4 4 4 4 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KER18582.1 - 1.8e-08 34.5 11.4 0.035 14.5 0.4 5.0 3 1 1 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER18582.1 - 1.4e-05 25.0 16.9 0.0092 16.0 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER18582.1 - 1.9e-05 24.8 11.8 0.18 12.1 1.5 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding BolA PF01722.18 KER18582.1 - 6.8e-05 23.1 2.0 0.21 11.9 0.0 3.2 2 1 1 3 3 3 1 BolA-like protein TF_Zn_Ribbon PF08271.12 KER18582.1 - 0.00023 20.6 5.4 0.0021 17.5 0.8 3.2 3 0 0 3 3 3 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KER18582.1 - 0.00039 20.5 11.1 0.52 10.5 0.0 3.8 2 2 1 3 3 3 3 Zinc ribbon domain zf-Di19 PF05605.12 KER18582.1 - 0.00068 19.9 12.9 0.0062 16.8 3.9 3.3 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KER18582.1 - 0.0017 17.9 2.6 0.16 11.6 0.0 3.2 3 0 0 3 3 3 1 MYST family zinc finger domain DUF2256 PF10013.9 KER18582.1 - 0.0038 17.3 11.7 0.059 13.5 0.3 4.1 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-nanos PF05741.13 KER18582.1 - 0.007 16.6 6.3 0.13 12.5 1.0 3.3 3 0 0 3 3 3 1 Nanos RNA binding domain A2L_zn_ribbon PF08792.10 KER18582.1 - 0.016 14.9 9.0 2.6 7.8 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain TerY_C PF15616.6 KER18582.1 - 0.017 15.2 2.4 0.065 13.4 2.4 2.0 1 1 0 1 1 1 0 TerY-C metal binding domain FYVE PF01363.21 KER18582.1 - 0.018 15.2 16.3 0.31 11.2 5.3 3.4 1 1 1 3 3 3 0 FYVE zinc finger zf-C2H2_2 PF12756.7 KER18582.1 - 0.027 14.8 12.8 0.4 11.0 1.2 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) PknG_rubred PF16919.5 KER18582.1 - 0.031 14.5 1.0 5.8 7.1 0.0 3.2 2 1 1 3 3 3 0 Protein kinase G rubredoxin domain zf_UBZ PF18439.1 KER18582.1 - 0.032 13.8 10.4 3.1 7.5 0.0 4.4 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 KER18582.1 - 0.034 14.1 12.3 2.2 8.3 0.2 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type CpXC PF14353.6 KER18582.1 - 0.043 13.9 9.1 8.2 6.5 0.1 3.8 1 1 3 4 4 4 0 CpXC protein zf-CHCC PF10276.9 KER18582.1 - 0.043 13.9 8.6 10 6.3 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.15 KER18582.1 - 0.044 13.9 10.0 18 5.5 0.2 4.2 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 KER18582.1 - 0.044 13.6 3.6 1.8 8.5 0.0 3.6 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 KER18582.1 - 0.053 13.5 1.7 0.37 10.8 0.0 2.9 3 1 1 4 4 3 0 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 KER18582.1 - 0.053 13.5 9.5 15 5.6 0.0 3.9 3 1 0 3 3 3 0 zinc-ribbon domain Actin_micro PF17003.5 KER18582.1 - 0.059 12.6 13.5 1.7 7.7 0.3 3.1 1 1 1 3 3 3 0 Putative actin-like family Cys_rich_CPXG PF14255.6 KER18582.1 - 0.12 12.3 4.5 4.9 7.1 0.0 3.7 3 1 0 3 3 2 0 Cysteine-rich CPXCG Prok-RING_1 PF14446.6 KER18582.1 - 0.13 12.3 11.1 6.2 6.8 1.4 4.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-piccolo PF05715.13 KER18582.1 - 0.21 11.8 0.3 0.21 11.8 0.3 2.5 2 1 1 3 3 3 0 Piccolo Zn-finger Cript PF10235.9 KER18582.1 - 0.22 12.1 6.1 3.4 8.3 0.8 3.5 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT DUF3268 PF11672.8 KER18582.1 - 0.26 11.6 2.9 1.8 8.9 0.1 2.4 2 1 0 2 2 2 0 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 KER18582.1 - 0.27 11.2 9.9 11 6.0 0.3 3.4 1 1 3 4 4 4 0 SprT-like zinc ribbon domain C1_2 PF03107.16 KER18582.1 - 0.29 11.5 10.3 11 6.4 0.0 4.0 3 1 0 3 3 3 0 C1 domain Zn_Tnp_IS1595 PF12760.7 KER18582.1 - 0.43 10.6 7.4 1.7 8.7 0.8 3.5 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Zf_RING PF16744.5 KER18582.1 - 0.44 10.7 8.0 2.8 8.1 0.3 3.3 2 1 1 3 3 3 0 KIAA1045 RING finger zf-C2H2_3 PF13878.6 KER18582.1 - 0.61 10.0 7.0 91 3.0 0.0 4.5 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_15 PF17032.5 KER18582.1 - 0.81 10.5 9.2 0.67 10.7 2.4 2.8 1 1 2 3 3 3 0 zinc-ribbon family zf-trcl PF13451.6 KER18582.1 - 0.81 9.6 13.4 5.4 7.0 0.2 4.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain zinc-ribbons_6 PF07191.12 KER18582.1 - 0.93 9.5 8.8 76 3.4 0.1 3.4 1 1 1 2 2 2 0 zinc-ribbons zf-RRN7 PF11781.8 KER18582.1 - 2 8.2 6.0 1 9.1 0.1 2.8 3 0 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rpr2 PF04032.16 KER18582.1 - 2.1 8.7 11.8 4 7.8 2.7 3.4 2 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYDLN_acid PF09538.10 KER18582.1 - 4.8 7.9 15.0 0.59 10.8 1.3 3.7 3 2 0 3 3 2 0 Protein of unknown function (FYDLN_acid) Vps39_2 PF10367.9 KER18582.1 - 5.4 7.5 12.5 5.5 7.5 0.4 3.9 1 1 3 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-CHY PF05495.12 KER18582.1 - 6.7 7.3 16.0 92 3.6 1.1 2.4 1 1 2 3 3 3 0 CHY zinc finger DUF2225 PF09986.9 KER18582.1 - 8.2 6.1 10.3 11 5.7 3.6 3.3 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Tnp_zf-ribbon_2 PF13842.6 KER18583.1 - 0.28 12.0 4.6 5.2 8.0 0.3 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C4 PF00105.18 KER18583.1 - 0.54 10.8 4.9 13 6.3 0.1 2.4 2 1 0 2 2 2 0 Zinc finger, C4 type (two domains) PNP_UDP_1 PF01048.20 KER18584.1 - 1.5e-41 142.2 1.1 2.6e-41 141.4 1.1 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily SBF PF01758.16 KER18585.1 - 0.0046 16.7 0.1 0.0088 15.7 0.1 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family Peptidase_M1 PF01433.20 KER18586.1 - 2.3e-39 135.2 5.5 2.5e-39 135.1 5.5 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain Aminopep PF10023.9 KER18586.1 - 0.0037 16.7 0.1 0.0044 16.4 0.1 1.1 1 0 0 1 1 1 1 Putative aminopeptidase Zincin_1 PF06262.11 KER18586.1 - 0.0085 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M48 PF01435.18 KER18586.1 - 0.059 13.1 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M48 Cu_amine_oxid PF01179.20 KER18587.1 - 6.4e-45 153.8 0.0 8.9e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Dynein_AAA_lid PF17852.1 KER18589.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Diphthamide_syn PF01866.17 KER18591.1 - 3e-18 66.3 0.0 3.3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.25 KER18592.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain RIBIOP_C PF04950.12 KER18597.1 - 2.3e-51 175.0 0.0 2.5e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DHC_N2 PF08393.13 KER18598.1 - 2.2e-70 237.8 0.4 2.4e-70 237.7 0.4 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 muHD PF10291.9 KER18600.1 - 0.00051 19.6 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain Homeodomain PF00046.29 KER18601.1 - 0.042 13.7 5.0 0.083 12.7 5.0 1.5 1 0 0 1 1 1 0 Homeodomain BRCT PF00533.26 KER18602.1 - 0.00094 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KER18602.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KER18602.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain C1_1 PF00130.22 KER18603.1 - 1.6e-06 27.9 2.5 3.6e-06 26.7 2.2 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.27 KER18603.1 - 1.9e-05 24.5 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain C1_2 PF03107.16 KER18603.1 - 0.017 15.4 1.3 0.027 14.8 1.3 1.4 1 0 0 1 1 1 0 C1 domain PHD_4 PF16866.5 KER18603.1 - 0.065 13.3 1.0 0.12 12.5 1.0 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KER18603.1 - 0.11 12.1 4.0 0.18 11.5 4.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KER18603.1 - 0.12 12.3 1.4 0.21 11.5 1.4 1.5 1 0 0 1 1 1 0 PHD-finger DZR PF12773.7 KER18603.1 - 0.38 10.8 3.6 0.41 10.7 2.1 1.9 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 KER18616.1 - 8e-45 153.3 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18616.1 - 6.4e-24 84.6 0.0 7.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER18616.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER18616.1 - 0.1 11.5 0.0 0.28 10.1 0.0 1.6 1 1 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KER18616.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CC190 PF15768.5 KER18616.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Asp PF00026.23 KER18620.1 - 1.5e-13 50.8 0.1 1.7e-13 50.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ig PF00047.25 KER18623.1 - 0.075 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain INCENP_ARK-bind PF03941.15 KER18625.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region ALIX_LYPXL_bnd PF13949.6 KER18627.1 - 2.4e-05 23.8 0.2 2.8e-05 23.6 0.2 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Ribosomal_L4 PF00573.22 KER18628.1 - 0.0026 17.5 0.8 0.003 17.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Aldo_ket_red PF00248.21 KER18630.1 - 1.5e-13 50.6 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YjcQ PF09639.10 KER18630.1 - 0.069 13.4 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 YjcQ protein YueH PF14166.6 KER18631.1 - 0.049 13.5 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 YueH-like protein DUF348 PF03990.14 KER18631.1 - 0.082 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Sulfotransfer_1 PF00685.27 KER18634.1 - 3.6e-45 154.5 0.0 4.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER18634.1 - 1e-05 26.0 0.0 5.9e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family CBS PF00571.28 KER18638.1 - 0.065 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 CBS domain SNF PF00209.18 KER18639.1 - 1.1e-17 64.0 0.6 1.3e-17 63.8 0.6 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LON_substr_bdg PF02190.16 KER18641.1 - 2.3e-07 30.9 0.0 2.5e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain F-box-like PF12937.7 KER18642.1 - 0.031 14.2 0.2 0.067 13.1 0.2 1.6 1 0 0 1 1 1 0 F-box-like HisKA PF00512.25 KER18643.1 - 0.00018 21.5 0.1 0.00025 21.0 0.1 1.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Aldo_ket_red PF00248.21 KER18644.1 - 1.7e-19 70.1 0.0 1.9e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C1 PF00112.23 KER18649.1 - 1.9e-58 198.2 0.1 2.5e-58 197.8 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER18649.1 - 0.0016 17.3 0.3 0.21 10.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Arf PF00025.21 KER18654.1 - 2.9e-15 56.1 0.0 3.1e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER18654.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain V-set PF07686.17 KER18655.1 - 9.4e-05 22.5 0.0 0.0058 16.8 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KER18655.1 - 0.11 12.5 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Pkinase PF00069.25 KER18658.1 - 8.8e-14 51.5 0.2 9.6e-14 51.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18658.1 - 0.00011 21.5 0.1 0.00013 21.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-S27 PF10037.9 KER18659.1 - 2.9e-47 161.4 0.3 3.3e-47 161.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Ub-Mut7C PF14451.6 KER18663.1 - 0.003 17.3 0.1 0.0071 16.2 0.1 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin E1-N PF14463.6 KER18665.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 E1 N-terminal domain DUF4619 PF15398.6 KER18672.1 - 0.027 14.0 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Golgin_A5 PF09787.9 KER18673.1 - 0.0016 18.0 0.3 0.0016 18.0 0.3 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2968 PF11180.8 KER18673.1 - 0.0047 16.6 5.2 0.0063 16.2 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Seryl_tRNA_N PF02403.22 KER18673.1 - 0.0071 16.6 0.3 0.011 16.0 0.3 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Med30 PF11315.8 KER18673.1 - 0.0088 16.2 0.8 0.012 15.8 0.8 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 Phage_GP20 PF06810.11 KER18673.1 - 0.012 15.5 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Fmp27_WPPW PF10359.9 KER18673.1 - 0.012 14.5 0.9 0.013 14.4 0.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 KER18673.1 - 0.019 14.3 1.3 0.022 14.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLATT_4 PF18186.1 KER18673.1 - 0.02 14.5 0.9 0.026 14.1 0.7 1.4 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 ZapB PF06005.12 KER18673.1 - 0.049 14.1 1.1 0.055 13.9 1.1 1.2 1 0 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 KER18673.1 - 0.078 13.2 1.6 0.11 12.6 1.6 1.2 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF3584 PF12128.8 KER18673.1 - 0.13 9.8 3.0 0.14 9.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 KER18673.1 - 0.16 11.3 5.4 0.11 11.8 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 KER18673.1 - 0.27 11.7 3.4 0.47 10.9 3.4 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KER18673.1 - 0.44 10.4 1.9 0.71 9.7 1.9 1.4 1 0 0 1 1 1 0 Septum formation initiator PDZ PF00595.24 KER18674.1 - 0.0014 19.0 0.1 0.0021 18.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Ofd1_CTDD PF10637.9 KER18676.1 - 1.3e-05 24.7 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term NOA36 PF06524.12 KER18676.1 - 0.078 12.3 1.3 0.087 12.1 1.3 1.0 1 0 0 1 1 1 0 NOA36 protein GOLD_2 PF13897.6 KER18676.1 - 0.15 12.5 0.8 0.18 12.3 0.8 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1041 PF06292.17 KER18677.1 - 5.4e-05 23.5 0.2 7.2e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PAN_4 PF14295.6 KER18678.1 - 0.038 13.9 1.3 0.069 13.1 1.3 1.5 1 1 0 1 1 1 0 PAN domain OATP PF03137.20 KER18679.1 - 2.5e-16 59.1 0.8 2.9e-16 58.9 0.8 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Holin_BhlA PF10960.8 KER18681.1 - 0.059 13.3 2.3 0.79 9.7 0.3 2.4 2 0 0 2 2 2 0 BhlA holin family Med15 PF09606.10 KER18681.1 - 0.097 11.3 8.4 0.12 11.1 8.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.14 KER18681.1 - 0.12 10.7 7.7 0.18 10.1 7.6 1.2 1 1 0 1 1 1 0 CDC45-like protein MAT1 PF06391.13 KER18681.1 - 0.14 11.9 13.8 0.2 11.5 13.8 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ABC_tran_Xtn PF12848.7 KER18681.1 - 0.48 10.5 6.6 0.42 10.7 1.2 2.3 2 0 0 2 2 2 0 ABC transporter Dicty_REP PF05086.12 KER18681.1 - 0.58 8.1 7.1 0.75 7.7 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phage_holin_2_4 PF16082.5 KER18681.1 - 7.2 6.4 5.4 0.62 9.8 0.5 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4404 PF14357.6 KER18683.1 - 0.18 12.5 5.9 0.28 11.9 2.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) IL17R_fnIII_D1 PF16556.5 KER18685.1 - 0.044 13.4 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 DUF2914 PF11141.8 KER18685.1 - 0.071 12.9 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF4270 PF14092.6 KER18686.1 - 0.025 13.7 0.0 0.025 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) RRM_1 PF00076.22 KER18686.1 - 0.026 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDPD PF03009.17 KER18689.1 - 1.9e-16 60.6 0.0 2.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 KER18689.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PAN_1 PF00024.26 KER18690.1 - 0.0023 17.8 0.2 0.0044 17.0 0.2 1.4 1 0 0 1 1 1 1 PAN domain zf_PR_Knuckle PF18445.1 KER18692.1 - 0.43 10.4 3.0 0.33 10.8 1.1 1.8 2 0 0 2 2 2 0 PR zinc knuckle motif Yippee-Mis18 PF03226.14 KER18694.1 - 1.2e-10 41.5 0.1 1.5e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 KER18694.1 - 0.011 15.6 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease Endonuclease_7 PF02945.15 KER18694.1 - 0.014 15.3 0.6 0.021 14.7 0.6 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII SelR PF01641.18 KER18694.1 - 0.024 14.7 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 SelR domain RIG-I_C-RD PF11648.8 KER18694.1 - 0.11 12.7 0.2 0.19 11.9 0.2 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Peptidase_C13 PF01650.18 KER18696.1 - 2.4e-20 73.1 0.3 3e-20 72.8 0.3 1.0 1 0 0 1 1 1 1 Peptidase C13 family Ribosomal_L36e PF01158.18 KER18697.1 - 3.1e-35 120.3 9.6 3.5e-35 120.1 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Tmemb_18A PF09771.9 KER18698.1 - 1.3e-10 41.7 0.0 1.4e-10 41.6 0.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 Sugar_tr PF00083.24 KER18701.1 - 1.7e-24 86.5 5.1 1.8e-24 86.4 5.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HisKA PF00512.25 KER18707.1 - 0.00018 21.5 0.1 0.00025 21.0 0.1 1.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RVT_1 PF00078.27 KER18708.1 - 9.7e-09 35.1 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIP PF00230.20 KER18709.1 - 4.3e-29 101.8 7.5 5.6e-29 101.5 7.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Na_H_antiport_2 PF13726.6 KER18709.1 - 0.57 10.3 5.8 2.7 8.2 0.7 2.8 2 1 0 2 2 2 0 Na+-H+ antiporter family Parvo_NS1 PF01057.17 KER18711.1 - 3.5e-19 68.9 0.0 3.7e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18711.1 - 2.4e-13 49.7 0.4 1.7e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 Papillomavirus helicase AAA_14 PF13173.6 KER18711.1 - 0.023 14.7 0.0 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KER18711.1 - 0.049 12.7 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KIP1 PF07765.12 KER18711.1 - 0.061 13.5 1.0 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 KIP1-like protein CdhD PF03599.16 KER18711.1 - 0.12 11.1 0.0 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit POT1 PF02765.17 KER18712.1 - 4.3e-07 29.9 0.0 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 RAD51_interact PF15696.5 KER18715.1 - 1.4e-07 31.5 1.0 3.6e-07 30.2 1.0 1.8 1 0 0 1 1 1 1 RAD51 interacting motif Sensor PF13796.6 KER18716.1 - 0.13 12.3 0.2 0.14 12.2 0.2 1.0 1 0 0 1 1 1 0 Putative sensor CCER1 PF15482.6 KER18717.1 - 0.066 13.1 2.6 0.088 12.7 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Capsid-VNN PF11729.8 KER18717.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein Amidohydro_1 PF01979.20 KER18718.1 - 2e-09 37.2 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KER18718.1 - 0.0003 20.4 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Izumo-Ig PF16706.5 KER18719.1 - 5.2e-06 26.4 0.3 0.55 10.3 0.0 3.8 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain ig PF00047.25 KER18719.1 - 0.00074 19.6 4.1 0.1 12.8 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.17 KER18719.1 - 0.00098 19.3 0.3 0.71 10.1 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KER18719.1 - 0.0071 16.7 3.9 4.6 7.7 0.1 3.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KER18719.1 - 0.037 14.1 0.6 9.6 6.3 0.1 3.1 3 0 0 3 3 3 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KER18719.1 - 0.056 14.0 2.8 7.4 7.3 0.1 3.8 3 0 0 3 3 3 0 Immunoglobulin domain Ig_6 PF18452.1 KER18719.1 - 1.7 8.3 5.4 18 5.0 0.1 3.3 3 0 0 3 3 3 0 Immunoglobulin domain RRM_1 PF00076.22 KER18722.1 - 2.2e-20 72.2 0.0 6.7e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Parvo_NS1 PF01057.17 KER18723.1 - 2.4e-13 49.8 0.2 9.2e-13 47.9 0.1 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER18723.1 - 2e-09 36.8 0.0 3.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Papillomavirus helicase AAA_7 PF12775.7 KER18723.1 - 0.064 12.8 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Tektin PF03148.14 KER18725.1 - 6.7e-35 120.6 0.9 7.4e-35 120.4 0.9 1.0 1 0 0 1 1 1 1 Tektin family PUB PF09409.10 KER18725.1 - 0.06 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 PUB domain DUF3989 PF13150.6 KER18725.1 - 0.11 12.2 0.1 0.34 10.7 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3989) zf-C2H2 PF00096.26 KER18734.1 - 4.8e-17 61.4 40.5 0.00042 20.6 0.2 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-met PF12874.7 KER18734.1 - 9.9e-16 57.5 20.4 0.00032 21.0 0.2 5.8 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER18734.1 - 9.8e-14 50.9 38.3 0.0059 17.3 0.3 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER18734.1 - 2.5e-09 37.1 35.7 0.00086 19.6 0.4 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER18734.1 - 1.3e-07 31.7 29.1 0.0028 17.9 0.2 6.1 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER18734.1 - 0.011 15.8 0.5 0.011 15.8 0.5 5.9 6 1 0 6 6 6 0 C2H2-type zinc finger GATA PF00320.27 KER18734.1 - 0.017 14.7 0.6 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 GATA zinc finger zf_C2H2_ZHX PF18387.1 KER18734.1 - 0.073 12.7 0.6 0.073 12.7 0.6 3.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KER18734.1 - 0.084 13.5 18.5 0.16 12.7 1.5 3.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KER18734.1 - 0.11 12.3 15.4 2.2 8.1 0.0 4.5 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 KER18734.1 - 0.26 12.1 8.7 0.48 11.2 1.9 2.8 3 0 0 3 3 2 0 zinc-ribbon family zf-C4pol PF14260.6 KER18734.1 - 0.3 11.6 8.5 1.4 9.4 4.3 2.5 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta KIND PF16474.5 KER18734.1 - 0.35 10.8 2.1 0.82 9.5 0.9 2.1 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain C1_4 PF07975.12 KER18734.1 - 0.38 11.0 14.2 0.56 10.5 2.8 3.3 3 0 0 3 3 3 0 TFIIH C1-like domain zf_UBZ PF18439.1 KER18734.1 - 0.41 10.3 12.9 6.8 6.4 0.3 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 KER18734.1 - 0.65 10.8 5.5 15 6.5 0.7 3.9 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF2256 PF10013.9 KER18734.1 - 0.87 9.7 9.6 10 6.3 0.4 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_2 PF03107.16 KER18734.1 - 1 9.7 18.1 16 5.9 0.1 4.1 2 1 1 3 3 3 0 C1 domain CpXC PF14353.6 KER18734.1 - 1.3 9.1 10.2 5.5 7.1 0.4 3.2 1 1 1 3 3 3 0 CpXC protein RNA_POL_M_15KD PF02150.16 KER18734.1 - 1.6 8.7 5.4 38 4.3 0.4 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.12 KER18734.1 - 2.6 8.1 11.4 92 3.1 8.3 3.5 2 1 0 2 2 2 0 zinc-ribbons zf-HIT PF04438.16 KER18734.1 - 8.8 6.3 15.6 1 9.3 0.6 4.2 4 0 0 4 4 4 0 HIT zinc finger Pkinase PF00069.25 KER18740.1 - 1.4e-24 86.9 0.0 1.7e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18740.1 - 3.8e-10 39.5 0.0 4.5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_1 PF00667.20 KER18743.1 - 2.2e-20 73.2 0.0 2.3e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain ABC_tran PF00005.27 KER18748.1 - 2.7e-13 50.6 0.0 3.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter EF-hand_8 PF13833.6 KER18750.1 - 1.7e-05 24.6 0.2 4.3e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KER18750.1 - 4e-05 24.0 0.5 7.3e-05 23.1 0.5 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER18750.1 - 0.0016 17.9 1.5 0.0027 17.1 0.4 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER18750.1 - 0.0066 16.3 0.8 0.029 14.3 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain Cation_efflux PF01545.21 KER18751.1 - 5.8e-07 29.4 0.2 6.5e-07 29.3 0.2 1.0 1 0 0 1 1 1 1 Cation efflux family HIG_1_N PF04588.13 KER18753.1 - 4.7e-08 33.1 1.9 7e-08 32.6 1.5 1.5 1 1 0 1 1 1 1 Hypoxia induced protein conserved region INT_SG_DDX_CT_C PF15300.6 KER18754.1 - 1.6e-16 59.8 0.0 3.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 KER18754.1 - 2.2e-12 47.6 0.0 4.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KER18754.1 - 0.0022 18.3 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ABC1 PF03109.16 KER18758.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KER18758.1 - 0.045 13.7 0.4 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5047 PF16466.5 KER18764.1 - 0.037 14.4 0.0 0.042 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5047) ABC_tran PF00005.27 KER18766.1 - 1e-11 45.5 0.0 1.8e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER18766.1 - 5.6e-07 29.2 0.0 7.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KER18766.1 - 0.0011 19.1 1.3 0.033 14.4 1.3 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Histone PF00125.24 KER18768.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER18768.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER18768.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KER18768.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 KER18768.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Sec34 PF04136.15 KER18771.1 - 0.00023 21.0 0.1 0.00028 20.8 0.1 1.1 1 0 0 1 1 1 1 Sec34-like family DUF948 PF06103.11 KER18771.1 - 0.0028 17.9 0.2 0.0045 17.2 0.2 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 KER18771.1 - 0.0062 16.6 0.5 0.011 15.8 0.4 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 GCIP PF13324.6 KER18771.1 - 0.0096 15.6 0.0 0.011 15.4 0.0 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF4298 PF14131.6 KER18771.1 - 0.011 15.7 0.2 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Helo_like_N PF17111.5 KER18771.1 - 0.013 14.9 0.5 0.044 13.1 0.1 1.8 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Fib_alpha PF08702.10 KER18771.1 - 0.014 15.6 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlgN PF05130.12 KER18771.1 - 0.035 14.6 0.1 0.06 13.9 0.1 1.4 1 1 0 1 1 1 0 FlgN protein ALIX_LYPXL_bnd PF13949.6 KER18771.1 - 0.079 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DASH_Duo1 PF08651.10 KER18771.1 - 0.086 12.6 1.1 1.9 8.3 0.4 2.6 1 1 2 3 3 3 0 DASH complex subunit Duo1 DUF2407 PF10302.9 KER18771.1 - 0.11 13.1 0.1 0.14 12.7 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Casc1_N PF15927.5 KER18771.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF1082 PF06449.11 KER18772.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) DUF4139 PF13598.6 KER18773.1 - 4.6e-17 62.4 0.0 6.9e-10 39.0 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) Ank_5 PF13857.6 KER18775.1 - 1.5e-11 44.3 0.5 7.5e-09 35.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER18775.1 - 9e-10 39.0 0.3 1.2e-07 32.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER18775.1 - 1.2e-09 38.2 0.3 1.1e-06 28.8 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KER18775.1 - 2.8e-08 34.1 0.4 4.1e-06 27.2 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER18775.1 - 3.2e-07 30.1 0.2 0.00011 22.3 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Hen1_L PF12623.7 KER18775.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 2Fe-2S_thioredx PF01257.19 KER18776.1 - 0.029 14.2 1.1 0.044 13.6 1.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Molybdopterin PF00384.22 KER18777.1 - 5.4e-19 68.5 0.0 2.3e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 Molybdopterin oxidoreductase RNA_pol_Rpb1_5 PF04998.17 KER18779.1 - 4.6e-18 65.6 0.0 4.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 LRRNT PF01462.18 KER18786.1 - 0.17 11.5 1.4 5.1 6.8 0.3 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain EndIII_4Fe-2S PF10576.9 KER18788.1 - 0.0072 16.6 2.0 0.013 15.8 2.0 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III DUF3384 PF11864.8 KER18788.1 - 0.22 10.4 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) RXLR_WY PF18634.1 KER18791.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Asp PF00026.23 KER18792.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic aspartyl protease RVT_1 PF00078.27 KER18796.1 - 2.1e-06 27.4 0.0 0.0001 21.9 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_UBOX PF13445.6 KER18805.1 - 0.0059 16.6 1.1 0.0059 16.6 1.1 2.3 3 0 0 3 3 3 1 RING-type zinc-finger Collagen PF01391.18 KER18807.1 - 1.2e-68 226.7 253.5 1.1e-10 41.0 29.8 8.5 1 1 4 5 5 5 3 Collagen triple helix repeat (20 copies) WD40 PF00400.32 KER18810.1 - 5.4e-12 46.0 0.3 0.00029 21.6 0.4 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER18810.1 - 2.9e-07 30.7 0.0 0.00019 21.7 0.0 2.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5466 PF17554.2 KER18810.1 - 0.034 14.3 0.1 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5466) PAN_1 PF00024.26 KER18817.1 - 0.0063 16.5 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 PAN domain EnY2 PF10163.9 KER18820.1 - 1.2e-25 89.7 0.2 1.3e-25 89.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 MMS19_N PF14500.6 KER18820.1 - 0.069 12.7 0.0 0.076 12.6 0.0 1.0 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Glyco_hydro_38C PF07748.13 KER18822.1 - 2.2e-12 47.5 0.0 1.9e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KER18822.1 - 1.4e-10 41.2 0.0 3.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain PUL PF08324.11 KER18823.1 - 1.7e-17 63.5 0.5 2.4e-17 63.1 0.5 1.3 1 0 0 1 1 1 1 PUL domain ATP19 PF11022.8 KER18823.1 - 0.053 13.9 0.1 11 6.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase subunit K Cas1_AcylT PF07779.12 KER18824.1 - 2.6e-17 62.9 8.4 2.8e-17 62.8 8.4 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p GSG-1 PF07803.11 KER18825.1 - 0.07 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 GSG1-like protein EGF PF00008.27 KER18827.1 - 5.9e-09 36.1 24.3 0.0013 18.9 5.3 3.7 3 1 0 3 3 3 3 EGF-like domain EGF_CA PF07645.15 KER18827.1 - 5e-08 33.0 31.7 0.0073 16.5 8.6 3.1 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 KER18827.1 - 1.5e-07 31.5 27.8 0.019 15.3 5.7 3.3 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KER18827.1 - 2.8e-06 27.1 25.5 0.00019 21.3 2.0 4.4 3 2 0 3 3 3 3 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 KER18827.1 - 3e-05 24.2 25.2 0.00068 19.9 7.3 3.5 2 1 1 3 3 3 3 Pvs28 EGF domain hEGF PF12661.7 KER18827.1 - 4.5e-05 23.9 30.4 0.0076 16.8 7.0 4.0 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_3 PF12947.7 KER18827.1 - 0.0008 19.6 25.7 0.022 15.0 1.2 3.9 4 1 0 4 4 4 3 EGF domain EGF_2 PF07974.13 KER18827.1 - 0.027 14.9 27.3 0.62 10.5 6.6 3.9 3 1 0 3 3 3 0 EGF-like domain RANK_CRD_2 PF18278.1 KER18827.1 - 4.4 7.5 15.5 10 6.4 2.9 3.5 3 1 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 eIF-1a PF01176.19 KER18828.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 Metallophos PF00149.28 KER18829.1 - 2.1e-22 80.6 0.0 3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER18829.1 - 0.021 15.2 0.8 0.051 14.0 0.8 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Viral_Rep PF02407.16 KER18830.1 - 3.4e-10 40.0 0.1 9.1e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Putative viral replication protein HTH_7 PF02796.15 KER18830.1 - 0.0083 16.2 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF433 PF04255.14 KER18830.1 - 0.013 15.4 0.0 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) RNA_helicase PF00910.22 KER18830.1 - 0.065 13.6 0.3 0.17 12.3 0.1 1.8 2 0 0 2 2 2 0 RNA helicase Circo_capsid PF02443.15 KER18831.1 - 0.084 12.4 0.0 0.084 12.4 0.0 2.3 2 1 0 2 2 2 0 Circovirus capsid protein Ras PF00071.22 KER18833.1 - 1.3e-36 125.6 0.0 1.4e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER18833.1 - 1.8e-20 73.4 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER18833.1 - 2.7e-11 43.2 0.0 2.9e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_2 PF12796.7 KER18836.1 - 2.1e-11 44.2 0.3 1.3e-05 25.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER18836.1 - 1.2e-07 31.8 2.4 0.33 11.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KER18836.1 - 0.00079 19.8 0.4 11 6.6 0.0 4.4 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KER18836.1 - 0.0024 18.2 7.6 4.5 8.2 0.1 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KER18836.1 - 0.039 14.5 5.0 5.4 7.7 0.5 4.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 KER18838.1 - 9.4e-07 28.0 0.6 9.4e-07 28.0 0.6 1.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KER18838.1 - 2.3e-06 27.3 0.3 2.9e-06 27.0 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER18838.1 - 0.0001 21.9 0.8 0.00025 20.7 0.3 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KER18838.1 - 0.00013 22.4 0.3 0.00016 22.0 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER18838.1 - 0.0014 18.1 0.6 0.0042 16.5 0.1 1.9 2 0 0 2 2 2 1 EF hand rve PF00665.26 KER18839.1 - 5e-22 78.3 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KER18839.1 - 2.2e-15 56.5 0.0 4.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER18839.1 - 5.3e-05 22.9 0.1 0.00026 20.7 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain PAN_1 PF00024.26 KER18843.1 - 0.0049 16.8 0.5 0.0067 16.4 0.5 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KER18843.1 - 0.0069 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 PAN domain Peptidase_C13 PF01650.18 KER18848.1 - 3.4e-55 187.3 5.5 6.7e-42 143.8 1.0 2.0 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER18848.1 - 3.3e-05 24.0 0.0 4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain ODR4-like PF14778.6 KER18851.1 - 0.15 11.0 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like Ribosomal_L30 PF00327.20 KER18852.1 - 3.8e-13 49.1 0.8 6.3e-13 48.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e LisH_TPL PF17814.1 KER18854.1 - 0.031 13.9 0.2 0.078 12.6 0.0 1.7 2 0 0 2 2 2 0 LisH-like dimerisation domain Asp PF00026.23 KER18855.1 - 3.3e-05 23.5 0.0 3.5e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease APP_E2 PF12925.7 KER18857.1 - 3.2e-11 43.3 13.9 2e-07 30.9 9.5 2.0 1 1 1 2 2 2 2 E2 domain of amyloid precursor protein Pou PF00157.17 KER18857.1 - 0.025 14.5 0.2 3.6 7.6 0.0 2.5 2 1 1 3 3 3 0 Pou domain - N-terminal to homeobox domain ABC_tran_CTD PF16326.5 KER18857.1 - 0.026 14.8 2.5 0.027 14.7 0.7 1.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Metal_resist PF13801.6 KER18857.1 - 0.032 14.4 7.7 0.99 9.6 1.5 2.4 1 1 1 2 2 2 0 Heavy-metal resistance TUDOR_5 PF18359.1 KER18857.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 tRNA_int_endo PF01974.17 KER18857.1 - 0.14 12.2 0.1 22 5.2 0.0 2.3 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain DUF4698 PF15769.5 KER18857.1 - 0.22 10.6 5.3 1.4 7.9 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4698) COXG PF06240.13 KER18858.1 - 0.035 13.9 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Vinculin PF01044.19 KER18859.1 - 6.1e-69 233.3 2.1 6.7e-69 233.2 2.1 1.0 1 0 0 1 1 1 1 Vinculin family Trp_repressor PF01371.19 KER18859.1 - 0.00021 21.3 0.2 0.46 10.6 0.0 2.4 2 1 0 2 2 2 2 Trp repressor protein Serine_rich PF08824.10 KER18859.1 - 0.025 14.6 0.3 0.2 11.7 0.0 2.2 1 1 0 2 2 2 0 Serine rich protein interaction domain Sec66 PF09802.9 KER18859.1 - 0.14 11.8 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 RRM_3 PF08777.11 KER18861.1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 KER18861.1 - 3.1e-05 23.7 0.0 9.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.7 KER18861.1 - 0.0013 18.8 0.2 0.0019 18.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_5 PF13893.6 KER18861.1 - 0.035 13.7 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1491 PF07372.12 KER18861.1 - 0.085 13.2 0.1 0.15 12.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) FG-GAP PF01839.23 KER18863.1 - 0.0056 16.8 3.0 0.014 15.5 3.0 1.7 1 1 0 1 1 1 1 FG-GAP repeat Cornichon PF03311.14 KER18864.1 - 7.3e-46 155.5 5.7 1.1e-45 154.9 5.7 1.2 1 0 0 1 1 1 1 Cornichon protein DHHC PF01529.20 KER18864.1 - 0.099 12.8 7.4 0.11 12.6 3.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase SLAC1 PF03595.17 KER18864.1 - 1.1 8.5 7.0 3.4 6.8 6.9 1.8 1 1 0 1 1 1 0 Voltage-dependent anion channel Aldedh PF00171.22 KER18867.1 - 1.3e-60 205.3 0.0 1.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BMC PF00936.19 KER18867.1 - 0.038 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 BMC domain RyR PF02026.16 KER18868.1 - 0.15 12.2 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 RyR domain Pkinase PF00069.25 KER18873.1 - 8.6e-57 192.5 0.0 1.3e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER18873.1 - 7.3e-35 120.5 0.0 2e-34 119.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.27 KER18873.1 - 6.4e-20 71.6 0.0 1.5e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Haspin_kinase PF12330.8 KER18873.1 - 0.00077 18.5 0.0 0.0024 16.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KER18873.1 - 0.0029 16.4 0.1 0.0061 15.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Exo_endo_phos_2 PF14529.6 KER18873.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Kinase-like PF14531.6 KER18873.1 - 0.04 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KER18873.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HOOK PF05622.12 KER18874.1 - 2e-20 72.6 9.7 5.1e-20 71.2 8.7 1.9 1 1 1 2 2 2 2 HOOK protein Serpin PF00079.20 KER18876.1 - 9.7e-55 186.4 0.0 1.1e-54 186.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_M13_N PF05649.13 KER18877.1 - 2.2e-09 37.5 0.0 3.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Ribosomal_L5 PF00281.19 KER18879.1 - 1.1e-21 76.9 0.4 7.5e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KER18879.1 - 2.5e-20 72.4 0.0 4.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus tRNA_anti-like PF12869.7 KER18879.1 - 0.16 11.6 0.5 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 tRNA_anti-like Peptidase_C13 PF01650.18 KER18880.1 - 5.7e-22 78.5 0.7 6.1e-22 78.4 0.7 1.0 1 0 0 1 1 1 1 Peptidase C13 family OTU PF02338.19 KER18881.1 - 2.6e-19 70.0 0.0 8.1e-19 68.4 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KER18881.1 - 6.4e-08 32.3 0.0 9.9e-06 25.2 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain KN_motif PF12075.8 KER18881.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 KN motif Arf PF00025.21 KER18884.1 - 2.5e-37 128.0 0.0 4.2e-32 111.0 0.0 2.9 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KER18884.1 - 2.9e-09 36.6 1.3 7.1e-07 28.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KER18884.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KER18884.1 - 0.00057 19.9 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KER18884.1 - 0.0012 18.3 0.0 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KER18884.1 - 0.018 14.7 0.0 0.044 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras family Gtr1_RagA PF04670.12 KER18884.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Proteasome PF00227.26 KER18885.1 - 6.8e-63 211.6 0.0 9.6e-63 211.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KER18885.1 - 3.3e-11 42.7 0.0 5.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_C13 PF01650.18 KER18886.1 - 4.8e-11 42.7 4.3 0.00012 21.7 0.0 2.9 2 1 1 3 3 3 2 Peptidase C13 family YidD PF01809.18 KER18886.1 - 0.15 11.9 1.1 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor Got1 PF04178.12 KER18888.1 - 2.1e-07 31.3 2.8 3.9e-07 30.5 2.8 1.5 1 0 0 1 1 1 1 Got1/Sft2-like family NADHdh PF00146.21 KER18893.1 - 2.9e-22 79.3 1.7 2.9e-22 79.3 1.7 2.1 2 1 1 3 3 3 1 NADH dehydrogenase COX1 PF00115.20 KER18893.1 - 2.7e-16 59.5 4.9 2.7e-16 59.5 4.9 2.2 1 1 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I Oxidored_q4 PF00507.19 KER18893.1 - 3.2e-07 30.4 11.2 3.2e-07 30.4 11.2 2.7 2 1 1 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 zf-C4 PF00105.18 KER18894.1 - 7.1e-28 96.9 14.9 1e-27 96.4 14.9 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF3413 PF11893.8 KER18895.1 - 0.015 14.5 1.0 0.018 14.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Peptidase_C13 PF01650.18 KER18899.1 - 7.5e-05 22.4 0.1 7.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family PnpCD_PnpD_N PF18191.1 KER18900.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal Trypsin PF00089.26 KER18902.1 - 1.2e-17 64.5 1.1 7.6e-17 61.9 1.1 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KER18902.1 - 0.013 16.4 0.3 0.033 15.1 0.3 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain PAN_1 PF00024.26 KER18905.1 - 0.015 15.2 5.5 0.021 14.8 5.5 1.5 1 1 0 1 1 1 0 PAN domain N-SET PF11764.8 KER18905.1 - 0.053 13.6 0.3 0.065 13.3 0.3 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N HAT_KAT11 PF08214.11 KER18908.1 - 1.1e-63 215.7 2.0 1.1e-63 215.7 2.0 2.2 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 KER18908.1 - 7.1e-21 74.1 0.3 1.9e-20 72.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 KER18908.1 - 4.9e-18 65.3 38.1 1.5e-13 51.0 14.7 4.4 4 0 0 4 4 3 2 TAZ zinc finger DUF902 PF06001.13 KER18908.1 - 3e-17 62.8 6.7 9.3e-17 61.2 6.7 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 KER18908.1 - 2e-12 47.2 0.7 5e-12 45.9 0.7 1.7 1 0 0 1 1 1 1 KIX domain ZZ PF00569.17 KER18908.1 - 2.3e-08 33.7 6.1 2.3e-08 33.7 6.1 4.3 5 0 0 5 5 5 1 Zinc finger, ZZ type CDC45 PF02724.14 KER18908.1 - 0.16 10.2 2.8 0.31 9.3 2.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C58 PF03543.14 KER18908.1 - 0.37 10.5 12.6 0.044 13.5 2.4 2.6 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF4611 PF15387.6 KER18908.1 - 2.5 8.4 8.5 6 7.2 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) MPM1 PF17234.2 KER18908.1 - 3 8.1 9.8 3.5 7.9 1.8 2.7 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4168 PF13767.6 KER18908.1 - 5.7 8.2 7.3 0.23 12.7 0.3 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4168) PcfK PF14058.6 KER18908.1 - 9.6 6.5 10.4 4.3 7.6 3.1 2.7 2 0 0 2 2 2 0 PcfK-like protein Ribosomal_L32e PF01655.18 KER18909.1 - 3.1e-45 153.0 5.0 3.7e-45 152.8 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Phosducin PF02114.16 KER18910.1 - 0.17 10.8 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin E1_DerP2_DerF2 PF02221.15 KER18913.1 - 0.002 18.6 0.1 0.0022 18.4 0.1 1.1 1 0 0 1 1 1 1 ML domain Collagen PF01391.18 KER18914.1 - 0.00026 20.7 4.0 0.00039 20.1 4.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HAGH_C PF16123.5 KER18915.1 - 2.7e-25 88.7 0.0 4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KER18915.1 - 1.9e-09 37.8 3.9 4.2e-08 33.4 3.1 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily UMPH-1 PF05822.12 KER18916.1 - 4.5e-49 167.2 0.0 9.7e-49 166.1 0.0 1.4 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 KER18916.1 - 0.00011 22.7 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cpn60_TCP1 PF00118.24 KER18917.1 - 6.2e-41 140.5 0.9 7.2e-41 140.3 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4156 PF13698.6 KER18917.1 - 0.067 13.5 0.2 0.22 11.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4156) AAA_33 PF13671.6 KER18917.1 - 0.07 13.3 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KER18919.1 - 1.5e-16 59.8 40.5 3.5e-05 24.0 0.5 6.0 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER18919.1 - 6.1e-14 51.5 38.9 0.0015 19.2 0.4 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER18919.1 - 1.4e-05 25.3 31.0 0.15 12.5 0.6 6.5 7 0 0 7 7 7 4 Zinc-finger double domain gag-asp_proteas PF13975.6 KER18919.1 - 0.017 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER18919.1 - 0.022 15.4 0.0 0.036 14.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2_11 PF16622.5 KER18919.1 - 0.041 13.6 0.7 0.041 13.6 0.7 5.6 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KER18919.1 - 0.041 14.2 13.4 2.9 8.3 0.0 4.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER18919.1 - 0.36 10.9 0.2 0.18 11.9 0.7 4.9 5 0 0 5 5 4 0 C2H2-type zinc finger FdhD-NarQ PF02634.15 KER18919.1 - 0.43 10.2 6.6 0.16 11.6 2.5 2.0 1 1 0 2 2 2 0 FdhD/NarQ family ADK_lid PF05191.14 KER18919.1 - 0.84 9.7 8.9 1.1 9.4 0.4 4.0 3 1 1 4 4 4 0 Adenylate kinase, active site lid zf-met PF12874.7 KER18919.1 - 1.3 9.5 12.8 5.2 7.6 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.7 KER18919.1 - 2.4 8.2 26.5 0.14 12.2 2.5 4.1 2 1 1 3 3 3 0 Double zinc ribbon zf-C2H2_8 PF15909.5 KER18919.1 - 2.7 8.4 9.4 1.3 9.4 5.1 2.6 1 1 2 3 3 3 0 C2H2-type zinc ribbon TF_Zn_Ribbon PF08271.12 KER18919.1 - 4.3 6.9 10.3 1.5 8.4 0.8 3.5 3 1 0 3 3 3 0 TFIIB zinc-binding SIR2 PF02146.17 KER18919.1 - 4.8 7.1 11.0 0.057 13.3 2.1 2.1 2 1 0 2 2 2 0 Sir2 family zf-C2H2_2 PF12756.7 KER18919.1 - 5.2 7.5 25.7 1.8 8.9 1.9 4.8 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KER18919.1 - 7.4 7.3 15.1 15 6.2 5.1 3.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KER18919.1 - 7.5 6.3 10.4 3.6 7.3 0.1 3.9 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Peptidase_C13 PF01650.18 KER18920.1 - 1.3e-90 303.4 1.8 3.6e-85 285.5 0.7 2.1 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER18920.1 - 0.0016 18.4 0.3 0.0033 17.4 0.1 1.6 2 0 0 2 2 2 1 Caspase domain PGP_phosphatase PF09419.10 KER18920.1 - 0.093 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Sulfotransfer_3 PF13469.6 KER18921.1 - 2e-22 80.6 0.1 5.3e-22 79.3 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase family DUF503 PF04456.12 KER18924.1 - 0.048 13.5 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Collagen PF01391.18 KER18925.1 - 0.043 13.6 0.4 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_S10 PF00338.22 KER18926.1 - 7.3e-26 90.3 0.2 8.4e-26 90.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1287 PF06940.11 KER18927.1 - 0.0049 16.5 0.1 4.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1287) FAM76 PF16046.5 KER18927.1 - 0.005 16.2 0.5 0.0072 15.7 0.5 1.2 1 0 0 1 1 1 1 FAM76 protein NYD-SP28 PF14772.6 KER18927.1 - 0.0081 16.2 3.8 0.022 14.8 3.8 1.7 1 1 0 1 1 1 1 Sperm tail SHR3_chaperone PF08229.11 KER18927.1 - 0.036 13.0 0.3 3.1 6.7 0.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 WD40 PF00400.32 KER18929.1 - 1.3e-05 25.8 0.0 0.27 12.2 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat PQQ PF01011.21 KER18929.1 - 0.0017 18.2 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat Peptidase_C13 PF01650.18 KER18931.1 - 1.3e-29 103.5 0.9 1.6e-29 103.2 0.9 1.1 1 0 0 1 1 1 1 Peptidase C13 family SPASM PF13186.6 KER18931.1 - 0.11 13.0 0.1 1.5 9.4 0.0 2.5 2 1 1 3 3 3 0 Iron-sulfur cluster-binding domain EamA PF00892.20 KER18936.1 - 0.17 12.1 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 EamA-like transporter family Peptidase_C13 PF01650.18 KER18937.1 - 3.9e-70 236.3 0.7 5.8e-70 235.7 0.7 1.2 1 0 0 1 1 1 1 Peptidase C13 family Vasohibin PF14822.6 KER18937.1 - 0.0067 15.7 0.3 4.8 6.3 0.0 3.3 4 0 0 4 4 4 2 Vasohibin GvpG PF05120.12 KER18937.1 - 0.029 14.4 0.6 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Gas vesicle protein G Pox_H7 PF04787.12 KER18937.1 - 0.031 14.8 1.2 0.34 11.4 0.3 2.4 1 1 1 2 2 2 0 Late protein H7 T4_Rnl2_C PF18043.1 KER18937.1 - 0.037 14.2 0.0 18 5.6 0.0 2.7 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Peptidase_C14 PF00656.22 KER18937.1 - 0.05 13.6 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Caspase domain zf-C3HC PF07967.13 KER18937.1 - 0.055 13.5 1.2 9.7 6.2 0.1 2.3 1 1 1 2 2 2 0 C3HC zinc finger-like NAD_binding_6 PF08030.12 KER18937.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PHA_synth_III_E PF09712.10 KER18940.1 - 0.1 11.7 0.3 0.099 11.7 0.3 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) NPC1_N PF16414.5 KER18941.1 - 3e-06 27.0 0.3 3.2e-06 26.9 0.3 1.0 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Acyl_transf_3 PF01757.22 KER18943.1 - 0.00055 19.1 9.8 0.00063 18.9 9.8 1.0 1 0 0 1 1 1 1 Acyltransferase family CUE PF02845.16 KER18945.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 CUE domain Ponericin PF07442.11 KER18945.1 - 0.95 9.6 3.8 14 5.8 0.2 2.3 2 0 0 2 2 2 0 Ponericin Peptidase_C13 PF01650.18 KER18948.1 - 0.044 13.3 0.2 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 Peptidase C13 family DEAD PF00270.29 KER18949.1 - 8.2e-44 149.4 2.1 1.3e-43 148.8 0.5 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER18949.1 - 2.2e-21 76.2 0.1 3.1e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER18949.1 - 7.3e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KER18949.1 - 0.00012 21.9 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER18949.1 - 0.00042 20.6 0.1 0.00097 19.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KER18949.1 - 0.0017 18.7 0.9 0.0028 18.0 0.9 1.5 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KER18949.1 - 0.038 13.9 0.2 0.11 12.5 0.2 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 KER18949.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Peptidase_C13 PF01650.18 KER18950.1 - 6.2e-60 202.9 0.4 7.8e-60 202.5 0.4 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER18950.1 - 0.00028 20.9 0.1 0.0003 20.8 0.1 1.2 1 0 0 1 1 1 1 Caspase domain RVT_1 PF00078.27 KER18957.1 - 0.00088 18.8 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KER18957.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KER18957.1 - 0.15 12.7 0.0 0.41 11.2 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RRM_1 PF00076.22 KER18958.1 - 8.5e-09 35.1 0.0 0.00063 19.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2399 PF09664.10 KER18958.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) PH PF00169.29 KER18960.1 - 0.039 14.5 0.1 0.052 14.1 0.1 1.2 1 0 0 1 1 1 0 PH domain Plk4_PB1 PF18190.1 KER18960.1 - 0.083 13.1 0.1 0.17 12.1 0.1 1.5 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 EF-hand_6 PF13405.6 KER18961.1 - 6e-10 38.2 4.3 0.003 17.4 0.2 4.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KER18961.1 - 3.7e-07 29.2 6.2 0.021 14.3 0.2 4.5 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 KER18961.1 - 5.7e-07 29.9 1.2 0.0096 16.4 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER18961.1 - 0.018 14.5 1.4 11 5.7 0.2 3.7 3 0 0 3 3 3 0 EF hand EFhand_Ca_insen PF08726.10 KER18961.1 - 0.081 13.0 0.1 1.4 9.1 0.0 2.8 2 1 0 2 2 2 0 Ca2+ insensitive EF hand PMM PF03332.13 KER18964.1 - 1.3e-70 237.7 0.5 2.4e-70 236.8 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Band_7 PF01145.25 KER18964.1 - 1.6e-09 38.1 0.1 1.2e-08 35.2 0.1 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Pkinase_fungal PF17667.1 KER18966.1 - 5.8e-05 22.1 0.0 8.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KER18966.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain UPAR_LY6_2 PF16975.5 KER18970.1 - 4.6e-05 23.6 0.5 5.8e-05 23.2 0.5 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Apolipoprotein PF01442.18 KER18972.1 - 0.0051 16.7 0.2 0.0074 16.2 0.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ferritin PF00210.24 KER18972.1 - 0.026 14.4 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Ferritin-like domain DALR_1 PF05746.15 KER18972.1 - 0.029 14.6 0.2 0.049 13.8 0.2 1.4 1 1 0 1 1 1 0 DALR anticodon binding domain Kunitz_BPTI PF00014.23 KER18974.1 - 3.1e-08 33.7 10.6 4.6e-08 33.2 10.6 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Oxysterol_BP PF01237.18 KER18975.1 - 8.8e-65 218.9 0.0 1.2e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein RVT_1 PF00078.27 KER18975.1 - 3.3e-06 26.8 0.4 8.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KER18978.1 - 3.5e-06 26.8 0.0 4.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C13 PF01650.18 KER18980.1 - 3.1e-40 138.3 5.9 3.8e-32 111.8 2.7 2.2 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER18980.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 Caspase domain EURL PF06937.11 KER18981.1 - 0.044 13.2 0.5 0.051 13.0 0.5 1.1 1 0 0 1 1 1 0 EURL protein FluMu_N PF17891.1 KER18981.1 - 0.091 12.5 0.0 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain PspA_IM30 PF04012.12 KER18983.1 - 0.006 16.2 0.4 0.0069 16.0 0.4 1.1 1 0 0 1 1 1 1 PspA/IM30 family Mut7-C PF01927.16 KER18983.1 - 0.068 13.3 0.2 0.096 12.8 0.2 1.3 1 1 0 1 1 1 0 Mut7-C RNAse domain BST2 PF16716.5 KER18983.1 - 0.073 13.7 2.1 0.12 13.0 2.1 1.4 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 B56 PF01603.20 KER18984.1 - 3.7e-91 306.2 0.9 4.1e-91 306.0 0.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Thioredoxin PF00085.20 KER18986.1 - 5.5e-61 203.0 0.1 1e-29 102.6 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 KER18986.1 - 3.8e-11 43.4 3.8 0.0015 19.0 0.1 5.0 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KER18986.1 - 2.3e-10 40.7 0.0 4.1e-06 26.8 0.0 2.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KER18986.1 - 7.6e-07 29.4 0.3 0.015 15.6 0.0 4.5 3 2 1 4 4 4 1 Thioredoxin-like OST3_OST6 PF04756.13 KER18986.1 - 2.1e-06 27.3 0.0 0.051 12.9 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 KER18986.1 - 2.2e-06 27.6 0.0 0.081 13.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_7 PF13899.6 KER18986.1 - 4.4e-06 26.8 0.1 0.091 13.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KER18986.1 - 6.1e-05 22.9 0.1 0.019 14.9 0.0 2.5 2 0 0 2 2 2 1 AhpC/TSA family HyaE PF07449.11 KER18986.1 - 0.0081 16.1 0.0 0.85 9.6 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KER18986.1 - 0.0086 15.9 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 3 1 F plasmid transfer operon protein DIM1 PF02966.16 KER18986.1 - 0.026 14.3 0.0 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Mitosis protein DIM1 FancD2 PF14631.6 KER18986.1 - 0.094 10.1 0.0 6.2 4.1 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Glutaredoxin PF00462.24 KER18986.1 - 0.18 12.0 1.6 19 5.6 0.1 3.1 2 2 0 2 2 2 0 Glutaredoxin Yippee-Mis18 PF03226.14 KER18989.1 - 3e-08 33.8 0.2 5.3e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LON_substr_bdg PF02190.16 KER18989.1 - 0.00029 20.8 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain Dynein_C PF18199.1 KER18990.1 - 2.8e-117 391.3 0.0 4.6e-117 390.6 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER18990.1 - 2.3e-80 268.9 0.7 3.9e-78 261.6 1.8 2.3 2 0 0 2 2 2 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 KER18990.1 - 4.9e-61 205.3 0.0 8.7e-61 204.5 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER18990.1 - 4.8e-47 158.9 0.0 2e-45 153.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DnaJ_C PF01556.18 KER18991.1 - 2.9e-35 121.5 0.0 3.3e-33 114.9 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 KER18991.1 - 6.2e-29 99.9 4.9 8.9e-26 89.8 2.7 2.3 2 0 0 2 2 2 2 DnaJ domain zf-CSL PF05207.13 KER18991.1 - 0.033 13.9 1.0 4.2 7.2 0.3 2.5 2 0 0 2 2 2 0 CSL zinc finger EGF_CA PF07645.15 KER18991.1 - 0.047 13.9 0.2 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain DFRP_C PF16543.5 KER18991.1 - 0.11 13.0 0.2 29 5.2 0.0 2.5 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 bZIP_1 PF00170.21 KER18991.1 - 0.52 10.4 3.3 23 5.2 0.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor Serpin PF00079.20 KER18992.1 - 8.4e-86 288.6 0.0 9.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_C13 PF01650.18 KER18994.1 - 1.8e-35 122.7 0.5 4.1e-34 118.2 0.4 2.1 2 0 0 2 2 2 2 Peptidase C13 family RRM_1 PF00076.22 KER18997.1 - 6e-19 67.6 0.0 1.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_3 PF13927.6 KER18998.1 - 9.4e-05 22.9 0.0 0.0074 16.9 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KER18998.1 - 0.00015 21.8 0.0 0.82 9.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain PorA PF11271.8 KER18998.1 - 0.0087 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Porin PorA PHD PF00628.29 KER19001.1 - 7.6e-08 32.1 8.7 7.6e-08 32.1 8.7 2.3 3 0 0 3 3 3 1 PHD-finger WSD PF15613.6 KER19001.1 - 0.015 15.7 1.0 0.12 12.8 0.0 3.0 3 0 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 KER19001.1 - 0.32 10.6 5.0 0.12 12.0 0.5 2.7 3 0 0 3 3 3 0 PHD-finger Pax2_C PF12403.8 KER19002.1 - 0.16 12.1 4.1 12 6.0 0.3 3.0 2 0 0 2 2 2 0 Paired-box protein 2 C terminal RabGAP-TBC PF00566.18 KER19003.1 - 2e-28 99.5 0.0 2.9e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 KER19003.1 - 8.4e-14 51.6 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19003.1 - 7.4e-08 32.0 0.0 2.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 KER19003.1 - 0.00043 20.8 0.0 0.0022 18.5 0.0 2.0 1 1 0 2 2 2 1 Rhodanese-like domain MULE PF10551.9 KER19004.1 - 1.3e-08 35.1 1.1 2.6e-08 34.1 0.5 1.9 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 KER19004.1 - 0.0011 18.7 0.3 0.0023 17.7 0.3 1.5 1 1 0 1 1 1 1 Transposase Peptidase_C13 PF01650.18 KER19006.1 - 2.2e-98 328.9 9.0 3.8e-82 275.6 1.0 3.1 2 1 1 3 3 3 3 Peptidase C13 family Peptidase_C14 PF00656.22 KER19006.1 - 2.5e-05 24.4 0.0 5.1e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Caspase domain MNE1 PF13762.6 KER19006.1 - 0.0098 15.9 0.6 4.4 7.3 0.2 2.6 2 0 0 2 2 2 2 Mitochondrial splicing apparatus component Succ_CoA_lig PF13607.6 KER19006.1 - 0.12 12.2 0.0 16 5.3 0.0 2.7 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain C5HCH PF17982.1 KER19006.1 - 0.17 12.1 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 NSD Cys-His rich domain Meiotic_rec114 PF03525.14 KER19008.1 - 0.087 11.8 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 DUF4538 PF15061.6 KER19009.1 - 0.029 14.1 0.8 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) HSP70 PF00012.20 KER19010.1 - 9.2e-155 516.2 0.0 1.1e-154 515.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER19010.1 - 1.1e-15 57.3 0.2 1.8e-14 53.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KER19010.1 - 0.00028 21.3 0.1 0.67 10.4 0.0 3.4 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KER19010.1 - 0.0018 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KER19010.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KER19010.1 - 0.13 11.5 0.1 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 StbA protein Raco_middle PF17651.1 KER19010.1 - 0.34 10.6 1.5 1.8 8.2 0.1 2.7 2 1 0 2 2 2 0 RACo middle region Peptidase_C13 PF01650.18 KER19016.1 - 8.4e-37 127.1 0.1 9.2e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER19017.1 - 1.5e-16 60.7 0.2 1.8e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF1192 PF06698.11 KER19018.1 - 0.012 15.6 0.1 0.023 14.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DNA_pol_viral_N PF00242.17 KER19018.1 - 0.17 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-CCHC PF00098.23 KER19019.1 - 2.2 8.5 8.3 0.13 12.4 3.0 1.8 2 0 0 2 2 2 0 Zinc knuckle Mut7-C PF01927.16 KER19021.1 - 0.0047 17.0 1.7 0.047 13.8 0.0 3.3 3 0 0 3 3 3 1 Mut7-C RNAse domain GAGA PF09237.11 KER19021.1 - 0.0062 16.3 0.9 0.94 9.3 0.0 3.9 3 0 0 3 3 3 1 GAGA factor Acetone_carb_G PF08882.11 KER19021.1 - 0.13 12.5 1.1 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit zf-H2C2_5 PF13909.6 KER19021.1 - 0.4 10.5 0.0 0.4 10.5 0.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KER19021.1 - 0.53 11.0 14.9 1.1 9.9 1.7 4.3 4 1 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KER19021.1 - 1.2 9.5 12.6 44 4.5 1.7 5.7 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KER19021.1 - 1.4 9.0 0.0 1.4 9.0 0.0 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KER19021.1 - 1.5 9.9 38.8 3.2 8.8 0.0 9.5 10 0 0 10 10 10 0 C2H2-type zinc finger PX PF00787.24 KER19022.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KER19022.1 - 0.093 12.3 1.6 0.9 9.0 0.8 2.1 2 0 0 2 2 2 0 Vps5 C terminal like HSP20 PF00011.21 KER19029.1 - 5.7e-29 100.3 0.3 1.9e-15 56.9 0.0 3.0 3 0 0 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KER19029.1 - 1.1e-05 24.9 0.0 0.00069 19.1 0.0 2.5 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Metal_resist PF13801.6 KER19029.1 - 0.053 13.7 1.5 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance B2-adapt-app_C PF09066.10 KER19031.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain NigD_N PF12667.7 KER19033.1 - 0.028 14.5 0.3 9.7 6.4 0.0 2.2 2 0 0 2 2 2 0 NigD-like N-terminal OB domain YTV PF07639.11 KER19033.1 - 0.24 11.5 1.6 20 5.3 0.2 2.4 2 0 0 2 2 2 0 YTV MRF_C2 PF13888.6 KER19034.1 - 0.39 10.6 4.2 0.86 9.5 4.2 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Tubulin PF00091.25 KER19036.1 - 8.3e-58 195.8 0.0 1.2e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER19036.1 - 3.4e-51 172.7 0.0 5.8e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER19036.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KER19036.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Peptidase_C13 PF01650.18 KER19037.1 - 3.4e-27 95.6 5.7 6.1e-16 58.7 0.8 3.2 2 1 1 3 3 3 3 Peptidase C13 family DUF4464 PF14713.6 KER19039.1 - 2.1e-66 223.7 0.0 2.3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF4464 PF14713.6 KER19040.1 - 1.6e-21 76.9 0.3 1.7e-21 76.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) LEM PF03020.15 KER19040.1 - 0.14 11.7 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 LEM domain Asp PF00026.23 KER19041.1 - 1.5e-25 90.3 0.0 1.8e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glyco_transf_4 PF13439.6 KER19042.1 - 8.8e-07 29.1 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_5 PF16994.5 KER19042.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl-transferase family 4 Glyco_trans_4_4 PF13579.6 KER19042.1 - 0.055 13.9 0.0 0.084 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DEAD_2 PF06733.15 KER19043.1 - 2.3e-47 160.9 1.0 3.9e-47 160.1 1.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KER19043.1 - 4.9e-46 157.0 0.0 1.2e-45 155.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 KER19043.1 - 1.6e-07 31.3 0.0 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase HBB PF06777.11 KER19043.1 - 0.00086 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain SNF2_N PF00176.23 KER19043.1 - 0.00093 18.0 0.1 0.0047 15.7 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KER19043.1 - 0.0023 18.0 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit RNase_P_p30 PF01876.16 KER19043.1 - 0.026 14.0 0.0 3.6 7.0 0.0 2.5 1 1 1 2 2 2 0 RNase P subunit p30 AAA_11 PF13086.6 KER19043.1 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sec6 PF06046.13 KER19044.1 - 7.7e-68 229.3 1.9 9.9e-68 228.9 1.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Bombinin PF05298.11 KER19044.1 - 0.05 13.3 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Bombinin RVT_1 PF00078.27 KER19046.1 - 1.8e-11 44.0 0.0 6.2e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KER19046.1 - 2e-05 24.3 0.0 0.069 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HELP PF03451.14 KER19047.1 - 0.18 11.7 0.6 12 5.8 0.0 2.4 2 1 1 3 3 3 0 HELP motif CAP PF00188.26 KER19048.1 - 6.8e-33 114.2 7.0 1.4e-24 87.3 4.7 2.2 2 0 0 2 2 2 2 Cysteine-rich secretory protein family SpoIIP PF07454.11 KER19048.1 - 0.0025 17.3 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein P (SpoIIP) PORR PF11955.8 KER19048.1 - 0.0056 15.7 0.3 0.082 11.8 0.1 2.0 2 0 0 2 2 2 1 Plant organelle RNA recognition domain DUF3849 PF12960.7 KER19048.1 - 0.0059 16.6 0.5 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3849) DUF3634 PF12321.8 KER19048.1 - 0.13 12.7 0.0 25 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) Tox-WTIP PF15654.6 KER19048.1 - 0.18 12.2 0.7 7.4 7.1 0.2 2.4 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif FA_desaturase PF00487.24 KER19049.1 - 2.5e-21 76.7 19.5 2.5e-21 76.7 19.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KER19049.1 - 1.8e-19 69.7 0.1 3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3270 PF11674.8 KER19049.1 - 0.016 15.4 0.9 0.041 14.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Peptidase_S74 PF13884.6 KER19053.1 - 0.12 12.7 0.1 6.7 7.1 0.0 2.1 1 1 1 2 2 2 0 Chaperone of endosialidase Pribosyltran PF00156.27 KER19054.1 - 4.2e-18 65.4 0.0 5.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EGF_Tenascin PF18720.1 KER19055.1 - 0.006 16.6 1.6 0.006 16.6 1.6 3.3 3 0 0 3 3 3 1 Tenascin EGF domain EGF PF00008.27 KER19055.1 - 0.018 15.3 1.0 0.018 15.3 1.0 6.3 4 2 0 4 4 4 0 EGF-like domain hEGF PF12661.7 KER19055.1 - 0.24 12.1 24.0 3.9 8.3 2.1 5.4 4 0 0 4 4 4 0 Human growth factor-like EGF CUB PF00431.20 KER19056.1 - 1.9e-12 47.5 0.1 2.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 CUB domain LTD PF00932.19 KER19056.1 - 0.0014 19.0 0.3 0.046 14.1 0.0 2.3 2 0 0 2 2 2 1 Lamin Tail Domain CUB PF00431.20 KER19057.1 - 3.8e-23 81.9 0.0 4.4e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 KER19057.1 - 0.0011 18.7 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 CUB-like domain IL4Ra_N PF09238.10 KER19057.1 - 0.031 14.6 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal Vps16_C PF04840.12 KER19060.1 - 0.0089 15.1 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region DUF3375 PF11855.8 KER19060.1 - 0.033 13.1 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) PAN_1 PF00024.26 KER19064.1 - 8.3e-05 22.5 0.5 0.00018 21.4 0.5 1.5 1 0 0 1 1 1 1 PAN domain DUF2742 PF10888.8 KER19064.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) PAN_4 PF14295.6 KER19064.1 - 9.6 6.2 7.3 0.51 10.3 1.7 1.7 2 0 0 2 2 2 0 PAN domain Pre-SET PF05033.16 KER19065.1 - 0.013 16.2 1.4 0.021 15.5 1.4 1.3 1 0 0 1 1 1 0 Pre-SET motif Linker_histone PF00538.19 KER19066.1 - 3.7e-08 33.6 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Csm2_III-A PF03750.13 KER19067.1 - 0.026 15.4 0.0 0.063 14.1 0.0 1.7 2 0 0 2 2 2 0 Csm2 Type III-A KRTDAP PF15200.6 KER19067.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated IP_trans PF02121.18 KER19070.1 - 2.6e-110 367.8 0.2 4.4e-110 367.1 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DDHD PF02862.17 KER19070.1 - 9.9e-34 117.4 1.3 4.8e-32 111.9 1.3 2.5 1 1 0 1 1 1 1 DDHD domain LNS2 PF08235.13 KER19070.1 - 0.12 11.8 0.0 2.7 7.4 0.0 2.4 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) FYVE_2 PF02318.16 KER19072.1 - 1.6e-20 73.5 9.0 1.6e-20 73.5 9.0 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 KER19072.1 - 1.7e-05 24.8 8.8 4.9e-05 23.4 8.8 1.6 1 1 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 KER19072.1 - 0.029 14.3 3.6 0.029 14.3 3.6 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.13 KER19072.1 - 0.46 10.2 6.7 0.087 12.5 2.2 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_10 PF16685.5 KER19072.1 - 2.7 8.2 9.1 6.3 7.0 9.1 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KER19072.1 - 3.7 7.5 7.3 6.6 6.7 7.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Efg1 PF10153.9 KER19072.1 - 3.8 7.9 10.2 0.07 13.5 0.9 2.6 2 1 1 3 3 3 0 rRNA-processing protein Efg1 zf-RING_2 PF13639.6 KER19072.1 - 6.1 7.3 8.6 11 6.4 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain IBR PF01485.21 KER19072.1 - 6.4 7.1 8.4 2.8 8.2 5.7 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain EGF PF00008.27 KER19074.1 - 0.00063 20.0 17.8 0.0045 17.3 0.5 3.6 3 1 0 3 3 3 2 EGF-like domain hEGF PF12661.7 KER19074.1 - 0.012 16.2 9.7 0.36 11.5 0.2 4.0 2 1 0 2 2 2 0 Human growth factor-like EGF FXa_inhibition PF14670.6 KER19074.1 - 0.32 11.3 6.6 0.92 9.8 6.6 1.9 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Sulfotransfer_3 PF13469.6 KER19075.1 - 1.7e-14 54.8 0.0 3.7e-09 37.3 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER19075.1 - 0.0018 17.8 0.0 0.13 11.7 0.0 2.8 2 1 0 2 2 2 2 Sulfotransferase domain Amino_oxidase PF01593.24 KER19077.1 - 2.2e-35 122.8 0.1 4.5e-24 85.5 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KER19077.1 - 1.3e-10 41.3 0.0 4.8e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KER19077.1 - 2e-06 27.6 2.0 4.4e-06 26.5 2.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KER19077.1 - 1.7e-05 24.2 0.3 2.6e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KER19077.1 - 3.6e-05 23.1 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KER19077.1 - 9.2e-05 21.7 0.9 0.00016 20.9 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KER19077.1 - 0.00047 19.6 0.8 0.0055 16.1 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KER19077.1 - 0.00078 18.3 0.2 0.0013 17.6 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KER19077.1 - 0.0029 18.1 0.3 0.026 15.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KER19077.1 - 0.0041 16.4 0.6 0.007 15.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KER19077.1 - 0.025 13.8 0.2 0.044 13.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KER19077.1 - 0.054 12.6 0.3 0.09 11.8 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KER19077.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RVT_1 PF00078.27 KER19077.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_3 PF13738.6 KER19077.1 - 0.37 10.0 0.9 0.56 9.4 0.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KER19079.1 - 1.5e-106 357.0 0.4 2.1e-106 356.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KER19079.1 - 2e-38 131.3 0.0 3e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KER19079.1 - 2.4e-06 27.0 0.1 0.0047 16.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KER19079.1 - 4.5e-05 22.8 0.4 0.00042 19.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KER19079.1 - 0.00036 19.7 1.8 0.0094 15.1 2.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KER19079.1 - 0.023 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KER19079.1 - 0.038 13.6 0.3 0.093 12.3 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KER19079.1 - 0.051 12.3 0.0 0.25 10.0 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein PCAF_N PF06466.11 KER19080.1 - 2.8e-51 174.5 7.9 4.8e-51 173.7 7.9 1.4 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 KER19080.1 - 1.9e-20 72.7 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain FYRC PF05965.14 KER19081.1 - 1e-23 83.3 0.0 2.5e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 KER19081.1 - 1.3e-20 73.0 1.1 3.6e-20 71.5 1.1 1.9 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KER19081.1 - 1.9e-13 51.2 0.2 1.1e-12 48.7 0.2 2.2 1 1 0 1 1 1 1 SET domain zf-HC5HC2H_2 PF13832.6 KER19081.1 - 6.6e-09 35.9 9.6 6.6e-09 35.9 9.6 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KER19081.1 - 4.2e-07 30.1 6.6 4.2e-07 30.1 6.6 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain DUF4614 PF15391.6 KER19082.1 - 5.3e-11 42.9 10.1 5.3e-11 42.9 10.1 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4614) Herpes_UL7 PF01677.16 KER19085.1 - 0.092 12.5 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like Bcl-2 PF00452.19 KER19087.1 - 4.6e-10 40.1 8.5 1.8e-08 35.0 0.8 3.1 2 1 0 2 2 2 2 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.6 KER19087.1 - 0.056 14.1 0.0 0.28 11.9 0.0 2.1 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like UCR_Fe-S_N PF10399.9 KER19087.1 - 0.78 9.1 3.3 2 7.8 3.3 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Neur_chan_LBD PF02931.23 KER19094.1 - 4.1e-13 49.3 0.6 5.1e-13 49.0 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER19094.1 - 0.001 19.2 3.0 0.0018 18.4 3.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region BRI3BP PF14965.6 KER19094.1 - 0.051 13.1 2.3 0.073 12.6 2.3 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF2070 PF09843.9 KER19094.1 - 0.085 11.1 2.2 0.097 10.9 2.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DEAD PF00270.29 KER19095.1 - 1.1e-10 41.6 0.2 2.5e-10 40.4 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 KER19095.1 - 0.013 15.5 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea INCENP_N PF12178.8 KER19095.1 - 0.065 13.2 0.3 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal ATP-synt_ab PF00006.25 KER19095.1 - 0.19 11.4 0.4 0.44 10.2 0.2 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pribosyltran PF00156.27 KER19099.1 - 3.9e-16 59.0 0.0 6.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Amastin PF07344.11 KER19101.1 - 0.017 15.0 1.0 0.025 14.4 1.0 1.2 1 0 0 1 1 1 0 Amastin surface glycoprotein Fibrillin_U_N PF18193.1 KER19101.1 - 3.4 7.9 6.8 14 5.9 0.4 2.7 1 1 1 2 2 2 0 Fibrillin 1 unique N-terminal domain Ribosomal_L19 PF01245.20 KER19102.1 - 4.1e-13 49.2 0.0 6.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_C13 PF01650.18 KER19104.1 - 4.8e-79 265.5 3.9 3.9e-78 262.5 3.9 2.0 1 1 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19104.1 - 0.0073 16.3 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Frag1 PF10277.9 KER19105.1 - 3.2e-21 75.9 20.2 4e-21 75.6 19.8 1.3 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Sema PF01403.19 KER19105.1 - 0.085 11.7 0.6 0.12 11.1 0.6 1.1 1 0 0 1 1 1 0 Sema domain FAD_binding_1 PF00667.20 KER19106.1 - 8.7e-66 221.7 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KER19106.1 - 6.3e-18 65.4 0.0 1.6e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KER19106.1 - 1.3e-14 54.8 0.0 5e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PID PF00640.23 KER19108.1 - 0.043 13.9 4.6 0.13 12.3 3.0 2.3 1 1 1 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Carboxyl_trans PF01039.22 KER19109.1 - 1.8e-188 627.2 0.0 2.1e-188 627.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain XK-related PF09815.9 KER19111.1 - 2.6e-99 332.5 32.5 3.6e-99 332.1 32.5 1.2 1 0 0 1 1 1 1 XK-related protein DUF4763 PF15960.5 KER19112.1 - 0.56 9.5 3.9 1.1 8.5 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YEATS PF03366.16 KER19113.1 - 5.3e-20 71.2 0.2 9.4e-20 70.4 0.2 1.4 1 0 0 1 1 1 1 YEATS family SseC PF04888.12 KER19113.1 - 0.54 9.8 2.1 0.87 9.1 2.1 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ndr PF03096.14 KER19114.1 - 2.1e-56 190.7 0.0 1.3e-42 145.5 0.0 2.1 1 1 1 2 2 2 2 Ndr family Abhydrolase_3 PF07859.13 KER19114.1 - 0.05 13.5 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold RVT_1 PF00078.27 KER19115.1 - 7.8e-06 25.6 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2202 PF09968.9 KER19115.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Symplekin_C PF12295.8 KER19115.1 - 0.052 13.6 0.1 0.061 13.4 0.1 1.0 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal ANAPC4_WD40 PF12894.7 KER19117.1 - 0.0012 19.1 0.0 0.036 14.4 0.0 3.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER19117.1 - 0.064 14.1 0.0 5.8 8.0 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat GIY-YIG PF01541.24 KER19118.1 - 2.7e-06 27.5 0.1 0.0073 16.6 0.0 2.5 2 0 0 2 2 2 2 GIY-YIG catalytic domain zinc_ribbon_6 PF14599.6 KER19118.1 - 0.0013 18.7 2.1 1.9 8.6 0.1 2.9 2 0 0 2 2 2 2 Zinc-ribbon KRTDAP PF15200.6 KER19118.1 - 0.0057 16.4 0.0 7.1 6.5 0.0 2.8 3 0 0 3 3 3 2 Keratinocyte differentiation-associated HTH_12 PF08461.10 KER19118.1 - 0.0065 16.4 1.3 4.7 7.2 0.1 2.6 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain DUF5501 PF17605.2 KER19118.1 - 0.0093 16.4 0.3 7.9 7.0 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5501) Herpes_UL49_2 PF04823.12 KER19118.1 - 0.015 15.4 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein Phage_base_V PF04717.12 KER19118.1 - 0.026 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector COX_ARM PF06481.14 KER19118.1 - 0.044 13.7 1.0 11 6.0 0.1 2.4 2 0 0 2 2 2 0 COX Aromatic Rich Motif Sigma70_r3 PF04539.16 KER19118.1 - 0.045 13.9 0.3 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 DUF5558 PF17713.1 KER19119.1 - 0.057 13.8 0.8 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Frag1 PF10277.9 KER19121.1 - 7.1e-38 130.3 14.9 8.1e-38 130.1 14.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3429 PF11911.8 KER19121.1 - 0.26 11.6 7.1 0.054 13.8 2.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3429) Virul_fac_BrkB PF03631.15 KER19121.1 - 0.67 9.5 10.2 0.17 11.5 4.1 2.4 2 1 0 2 2 2 0 Virulence factor BrkB Bax1-I PF01027.20 KER19121.1 - 7.3 6.4 17.7 3.1 7.6 11.9 2.6 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Frag1 PF10277.9 KER19122.1 - 7.2e-19 68.2 10.8 8.2e-19 68.0 10.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TPPK_C PF12555.8 KER19122.1 - 0.62 10.2 3.9 0.33 11.0 0.8 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal 4HBT PF03061.22 KER19123.1 - 1e-07 32.2 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KER19123.1 - 0.0044 17.3 0.0 0.0075 16.5 0.0 1.2 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4761 PF15958.5 KER19123.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Ribosomal_S4Pg PF11993.8 KER19123.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) FbpA PF05833.11 KER19124.1 - 3.8e-30 105.1 9.6 1.1e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KER19124.1 - 1.7e-28 99.5 0.0 5.5e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KER19124.1 - 3.1e-27 94.6 0.0 3.1e-27 94.6 0.0 2.4 3 0 0 3 3 3 1 NFACT protein C-terminal domain DUF5590 PF17881.1 KER19124.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) CSRNP_N PF16019.5 KER19127.1 - 2.3e-63 214.1 20.8 1.1e-37 130.0 14.9 3.2 3 0 0 3 3 3 3 Cysteine/serine-rich nuclear protein N-terminus FOXP-CC PF16159.5 KER19128.1 - 6.9e-08 33.0 25.4 0.44 11.2 1.2 7.2 4 2 3 7 7 7 4 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KER19128.1 - 1.2e-05 25.7 54.2 0.063 14.1 0.5 8.2 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER19128.1 - 0.043 14.1 17.2 0.24 11.7 1.7 4.4 1 1 4 5 5 5 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KER19128.1 - 0.075 13.5 0.7 0.075 13.5 0.7 7.9 8 0 0 8 8 8 0 Zinc finger, C2H2 type OrsD PF12013.8 KER19128.1 - 0.084 13.3 0.1 0.084 13.3 0.1 5.6 6 1 1 7 7 7 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-DNA_Pol PF08996.10 KER19128.1 - 0.13 12.0 9.8 0.4 10.4 0.6 3.6 2 1 2 4 4 4 0 DNA Polymerase alpha zinc finger Apolipoprotein PF01442.18 KER19129.1 - 5.1e-06 26.5 6.5 1.9e-05 24.6 2.0 2.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF386 PF04074.12 KER19129.1 - 0.018 14.9 0.2 0.041 13.8 0.2 1.6 1 1 0 1 1 1 0 YhcH/YjgK/YiaL Emaravirus_P4 PF16505.5 KER19129.1 - 0.021 13.9 0.8 0.034 13.2 0.8 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Vps54_N PF10475.9 KER19129.1 - 0.13 11.5 2.3 0.55 9.5 0.1 2.0 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Prominin PF05478.11 KER19129.1 - 0.14 10.1 3.8 0.11 10.4 1.9 1.5 1 1 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 KER19129.1 - 0.2 11.7 4.2 5.7 7.0 0.8 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 KER19129.1 - 0.22 11.1 7.6 1.5 8.4 7.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) pRN1_helical PF13010.6 KER19129.1 - 0.23 11.4 2.2 0.18 11.8 0.5 1.7 2 0 0 2 2 2 0 Primase helical domain Med9 PF07544.13 KER19129.1 - 0.23 11.5 6.3 0.16 12.1 2.6 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Uteroglobin PF01099.17 KER19129.1 - 0.29 11.5 5.8 0.67 10.3 1.5 3.1 2 1 1 3 3 3 0 Uteroglobin family Prefoldin_2 PF01920.20 KER19129.1 - 0.31 11.0 12.0 0.44 10.5 0.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit DUF883 PF05957.13 KER19129.1 - 0.32 11.6 4.4 1.7 9.3 0.5 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PEP-utilisers_N PF05524.13 KER19129.1 - 0.4 10.9 1.7 2.5 8.3 0.2 2.4 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4363 PF14276.6 KER19129.1 - 0.46 10.6 6.0 0.38 10.9 1.2 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) DUF2433 PF10360.9 KER19129.1 - 0.57 10.3 3.1 1.8 8.7 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2433) CHIP_TPR_N PF18391.1 KER19129.1 - 0.72 10.7 0.1 0.72 10.7 0.1 2.5 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain GrpE PF01025.19 KER19129.1 - 1.1 8.9 6.9 0.36 10.5 3.0 1.9 2 0 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 KER19129.1 - 1.3 9.3 10.1 3.5 7.9 3.6 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YtxH PF12732.7 KER19129.1 - 1.4 9.5 9.0 5.3 7.6 5.6 3.0 1 1 1 2 2 2 0 YtxH-like protein SlyX PF04102.12 KER19129.1 - 9.3 6.9 6.9 16 6.2 0.1 3.5 2 2 1 3 3 3 0 SlyX Ada_Zn_binding PF02805.16 KER19133.1 - 0.0072 16.3 0.2 6.7 6.8 0.1 2.9 2 0 0 2 2 2 2 Metal binding domain of Ada FBD PF08387.10 KER19133.1 - 0.0079 16.1 0.2 7.1 6.6 0.0 2.9 2 0 0 2 2 2 2 FBD QueF PF14489.6 KER19133.1 - 0.037 14.2 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 QueF-like protein UBZ_FAAP20 PF15750.5 KER19133.1 - 0.36 10.8 5.5 12 5.9 0.5 3.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Fer4_3 PF12798.7 KER19133.1 - 4.3 8.5 6.7 69 4.7 0.8 3.6 2 0 0 2 2 2 0 4Fe-4S binding domain Trypsin PF00089.26 KER19134.1 - 5.8e-17 62.3 1.7 8.2e-16 58.5 1.7 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KER19134.1 - 0.0041 18.0 0.0 0.013 16.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain YecM PF06185.12 KER19134.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 YecM protein Serpin PF00079.20 KER19135.1 - 3.8e-17 62.7 0.0 4.4e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Guanylin PF02058.15 KER19136.1 - 0.084 13.4 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Guanylin precursor Ferrochelatase PF00762.19 KER19137.1 - 3.9e-95 318.6 0.0 5.6e-95 318.1 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase RVT_1 PF00078.27 KER19137.1 - 1.8e-10 40.7 0.0 3.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FGase PF05013.12 KER19137.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase Ank_2 PF12796.7 KER19138.1 - 8.3e-20 71.2 3.2 2.7e-07 31.1 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER19138.1 - 8.9e-16 57.8 3.6 2.8e-06 27.5 0.1 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Notch PF00066.17 KER19138.1 - 2.1e-15 56.8 29.1 1.4e-11 44.6 10.9 4.8 4 0 0 4 4 4 2 LNR domain Ank_4 PF13637.6 KER19138.1 - 3e-11 43.6 1.6 1.4e-05 25.6 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) NODP PF07684.12 KER19138.1 - 1.5e-10 41.1 0.0 5.5e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 NOTCH protein Ank PF00023.30 KER19138.1 - 1.7e-10 40.8 3.2 0.0031 17.9 0.4 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KER19138.1 - 1.1e-09 37.7 1.1 0.11 13.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat EGF PF00008.27 KER19138.1 - 0.004 17.4 78.2 0.0093 16.3 6.1 8.7 8 1 0 8 8 8 5 EGF-like domain wnt PF00110.19 KER19140.1 - 5.1e-49 167.5 1.3 6.4e-49 167.2 1.3 1.0 1 0 0 1 1 1 1 wnt family ribosomal_L24 PF17136.4 KER19141.1 - 1.2e-06 28.8 0.0 3.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 EF-hand_8 PF13833.6 KER19141.1 - 2.5e-06 27.2 0.0 8.9e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER19141.1 - 1.2e-05 24.6 0.7 0.00019 20.8 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KER19141.1 - 5.4e-05 22.8 0.1 0.0011 18.7 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KER19141.1 - 0.00014 22.2 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER19141.1 - 0.00049 19.5 3.8 0.0028 17.1 0.1 2.8 3 0 0 3 3 3 1 EF hand KOW PF00467.29 KER19141.1 - 0.0019 18.1 2.0 0.0019 18.1 2.0 1.8 2 0 0 2 2 2 1 KOW motif Pyr_redox_2 PF07992.14 KER19143.1 - 7.9e-43 146.8 0.0 1.8e-42 145.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KER19143.1 - 5.4e-30 103.9 0.1 1e-29 103.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KER19143.1 - 8.1e-14 51.9 0.0 2.9e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KER19143.1 - 1.8e-12 47.1 0.0 2.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KER19143.1 - 0.038 13.1 0.0 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pec_lyase_C PF00544.19 KER19143.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Pectate lyase MoaC PF01967.21 KER19145.1 - 6.8e-38 129.8 1.0 1.2e-37 129.0 0.5 1.6 1 1 0 1 1 1 1 MoaC family DRTGG PF07085.12 KER19145.1 - 0.0096 15.7 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 2 DRTGG domain Bacteriocin_II PF01721.18 KER19145.1 - 0.55 10.4 0.2 0.55 10.4 0.2 1.8 2 0 0 2 2 2 0 Class II bacteriocin Mob_synth_C PF06463.13 KER19146.1 - 2.6e-32 111.5 0.0 5.2e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KER19146.1 - 6.7e-26 91.6 0.0 1.1e-25 91.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KER19146.1 - 4.2e-07 30.3 0.0 8.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KER19146.1 - 9e-07 29.0 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain LEDGF PF11467.8 KER19146.1 - 0.017 14.7 0.0 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) AAA PF00004.29 KER19147.1 - 3.3e-30 105.2 0.0 4.5e-29 101.5 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Telomere_reg-2 PF10193.9 KER19147.1 - 1.4e-19 70.5 0.0 4.7e-19 68.8 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein AAA_22 PF13401.6 KER19147.1 - 8.6e-07 29.3 0.1 8.2e-06 26.1 0.0 2.6 3 1 0 3 3 1 1 AAA domain AAA_18 PF13238.6 KER19147.1 - 2.8e-06 27.9 0.0 7.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER19147.1 - 3.7e-05 24.2 0.2 0.00027 21.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KER19147.1 - 0.00021 21.6 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KER19147.1 - 0.00071 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KER19147.1 - 0.00076 19.5 0.4 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KER19147.1 - 0.00086 19.7 0.0 0.0045 17.4 0.0 2.3 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 KER19147.1 - 0.0032 17.2 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KER19147.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER19147.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KER19147.1 - 0.0058 15.8 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KER19147.1 - 0.0085 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KER19147.1 - 0.009 15.8 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KER19147.1 - 0.0099 15.5 0.1 0.043 13.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KER19147.1 - 0.012 15.6 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 KER19147.1 - 0.014 14.1 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KER19147.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KER19147.1 - 0.015 15.2 0.0 0.34 10.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KER19147.1 - 0.017 15.1 0.0 0.061 13.3 0.0 2.1 1 0 0 1 1 1 0 NACHT domain AAA_2 PF07724.14 KER19147.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 KER19147.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PduV-EutP PF10662.9 KER19147.1 - 0.028 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KER19147.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KER19147.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KER19147.1 - 0.058 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KER19147.1 - 0.076 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KER19147.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KER19147.1 - 0.19 12.1 0.1 0.58 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KER19148.1 - 0.0079 15.7 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEFB136 PF17333.2 KER19149.1 - 0.074 13.0 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Beta defensin 136 CXCL17 PF15211.6 KER19149.1 - 0.17 12.7 4.1 0.44 11.3 2.4 2.1 1 1 1 2 2 2 0 VEGF co-regulated chemokine 1 Rrf2 PF02082.20 KER19150.1 - 0.019 15.3 0.0 13 6.2 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator Tubulin_C PF03953.17 KER19151.1 - 1.1e-22 80.5 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_C PF03953.17 KER19152.1 - 1.1e-22 80.5 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain He_PIG_assoc PF10632.9 KER19154.1 - 0.045 13.4 0.8 0.11 12.2 0.8 1.7 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Actin PF00022.19 KER19155.1 - 7.4e-20 70.9 0.2 1.8e-19 69.7 0.1 1.6 2 0 0 2 2 2 1 Actin Pribosyltran PF00156.27 KER19158.1 - 3.8e-17 62.3 0.0 6.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MRP-S27 PF10037.9 KER19160.1 - 1.1e-18 67.3 0.1 1.5e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 SRA1 PF07304.11 KER19161.1 - 0.22 11.3 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) HRM PF02793.22 KER19164.1 - 1.1e-10 41.6 1.3 2.3e-10 40.6 1.3 1.5 1 0 0 1 1 1 1 Hormone receptor domain Nop14 PF04147.12 KER19165.1 - 0.042 12.1 11.4 0.039 12.2 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KER19165.1 - 0.081 12.2 22.1 0.094 12.0 22.1 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KER19165.1 - 0.13 11.9 25.8 0.15 11.7 25.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 KER19165.1 - 0.6 8.6 14.0 0.59 8.6 14.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 KER19165.1 - 0.73 9.7 12.2 0.82 9.5 12.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 KER19165.1 - 2.2 6.4 13.4 2.5 6.3 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KER19165.1 - 2.5 7.6 12.3 2.4 7.7 12.3 1.1 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KER19165.1 - 6.9 5.9 13.1 7.4 5.8 13.1 1.0 1 0 0 1 1 1 0 BUD22 7tm_2 PF00002.24 KER19166.1 - 4e-06 26.3 0.6 6.5e-06 25.6 0.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pkinase PF00069.25 KER19167.1 - 6e-24 84.8 0.0 8.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19167.1 - 1e-15 57.8 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Asp PF00026.23 KER19171.1 - 3.2e-22 79.4 0.0 3.5e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ion_trans PF00520.31 KER19173.1 - 3.6e-170 563.5 64.8 2.5e-57 194.0 15.6 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 KER19173.1 - 2.2e-26 91.8 0.1 5.1e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KER19173.1 - 2.6e-25 87.9 0.1 7e-25 86.6 0.1 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KER19173.1 - 6.3e-12 44.9 63.5 7.3e-05 21.6 7.4 8.1 5 3 3 8 8 8 7 Polycystin cation channel DUF4834 PF16118.5 KER19173.1 - 0.13 13.3 4.7 12 6.9 0.0 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) DUF1073 PF06381.11 KER19174.1 - 0.14 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) DUF2888 PF11135.8 KER19175.1 - 0.035 14.1 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Ion_trans PF00520.31 KER19176.1 - 2.7e-43 148.0 2.8 8e-28 97.3 0.2 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KER19176.1 - 0.0048 15.6 4.7 0.2 10.3 0.1 2.1 2 0 0 2 2 2 2 Polycystin cation channel TACC_C PF05010.14 KER19178.1 - 0.0037 17.1 3.2 0.0053 16.6 3.2 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CLZ PF16526.5 KER19178.1 - 0.085 13.2 2.0 0.19 12.1 2.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_25 PF13481.6 KER19181.1 - 6.2e-15 55.3 0.0 2.7e-14 53.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.15 KER19181.1 - 1.5e-10 40.9 0.0 4.5e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KER19181.1 - 1.7e-05 25.1 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER19181.1 - 0.00017 21.0 0.0 0.00048 19.5 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 KER19181.1 - 0.00043 20.7 0.0 0.00077 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KER19181.1 - 0.0068 16.2 0.3 0.061 13.1 0.0 2.4 2 1 1 3 3 3 1 IstB-like ATP binding protein NACHT PF05729.12 KER19181.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KER19181.1 - 0.024 14.3 0.0 0.075 12.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER19181.1 - 0.035 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KER19181.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArsA_ATPase PF02374.15 KER19181.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.23 KER19181.1 - 0.1 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KER19181.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KER19181.1 - 0.15 12.5 0.7 0.32 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Dynein_light PF01221.18 KER19183.1 - 1.6e-34 118.1 0.1 1.7e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Calreticulin PF00262.18 KER19185.1 - 1.2e-149 498.2 11.8 1.2e-149 498.2 11.8 1.5 2 0 0 2 2 2 1 Calreticulin family DUF5323 PF17257.2 KER19185.1 - 0.025 14.4 0.9 0.065 13.1 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5323) NT5C PF06941.12 KER19185.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF3368 PF11848.8 KER19186.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) HRCT1 PF15758.5 KER19186.1 - 0.13 13.2 0.7 0.31 12.0 0.7 1.6 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 ABC_membrane PF00664.23 KER19189.1 - 9.1e-31 107.5 10.3 1.3e-30 107.0 10.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region RibD_C PF01872.17 KER19189.1 - 0.067 13.0 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain DUF2053 PF09767.9 KER19189.1 - 0.29 11.3 5.4 0.56 10.3 5.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) CRAL_TRIO_2 PF13716.6 KER19190.1 - 0.053 13.7 0.0 1.6 8.9 0.0 2.3 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain rve PF00665.26 KER19191.1 - 6.5e-19 68.3 0.0 9.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KER19191.1 - 6.1e-06 26.3 0.5 1.3e-05 25.2 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER19191.1 - 0.00038 20.2 0.0 0.0035 17.1 0.0 2.4 1 1 1 2 2 2 1 Integrase core domain Neuralized PF07177.12 KER19192.1 - 8.4e-21 74.5 0.0 2.5e-17 63.3 0.0 2.5 2 1 0 2 2 2 2 Neuralized ThiF PF00899.21 KER19193.1 - 4.5e-47 160.5 0.0 6.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KER19193.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KER19193.1 - 0.0045 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KER19193.1 - 0.016 15.6 0.0 0.058 13.8 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KER19193.1 - 0.026 14.8 1.4 0.76 10.0 1.4 2.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CLZ PF16526.5 KER19193.1 - 0.065 13.6 2.1 3.6 8.0 0.8 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KER19193.1 - 0.11 12.5 0.7 0.23 11.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlxA PF14282.6 KER19193.1 - 0.21 11.6 0.1 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 FlxA-like protein FabA PF07977.13 KER19194.1 - 0.072 12.7 0.0 1.1 8.9 0.0 1.9 1 1 1 2 2 2 0 FabA-like domain Peptidase_C13 PF01650.18 KER19195.1 - 1.5e-15 57.4 6.2 1.8e-10 40.8 0.2 3.1 1 1 2 3 3 3 3 Peptidase C13 family DprA_WH PF17782.1 KER19196.1 - 0.09 12.9 0.0 0.41 10.8 0.0 2.2 1 0 0 1 1 1 0 DprA winged helix domain zf-C2H2_jaz PF12171.8 KER19196.1 - 1.3 9.4 8.1 4 7.8 1.5 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.32 KER19197.1 - 6.9e-34 115.3 28.7 2e-05 25.2 0.1 11.6 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER19197.1 - 1.7e-08 34.6 0.4 6.1 7.2 0.0 7.3 3 3 5 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER19197.1 - 0.002 17.5 7.1 0.0032 16.8 0.1 3.9 3 2 2 5 5 5 2 WD40-like domain CPSF_A PF03178.15 KER19197.1 - 0.045 13.1 0.5 0.51 9.6 0.0 3.0 4 0 0 4 4 4 0 CPSF A subunit region PGI PF00342.19 KER19198.1 - 6.2e-197 655.0 0.6 1.6e-154 515.1 0.2 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Peptidase_C13 PF01650.18 KER19199.1 - 3e-76 256.3 3.8 3.1e-65 220.2 1.2 2.1 1 1 1 2 2 2 2 Peptidase C13 family PheRS_DBD2 PF18554.1 KER19199.1 - 0.027 14.4 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Peptidase_C13 PF01650.18 KER19200.1 - 1.6e-96 322.7 1.5 2.3e-96 322.3 1.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19200.1 - 0.019 14.9 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Caspase domain POT1 PF02765.17 KER19201.1 - 1.2e-27 96.5 0.0 1.4e-26 93.0 0.0 2.5 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KER19201.1 - 2.8e-20 72.7 0.0 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein tRNA_anti-codon PF01336.25 KER19201.1 - 0.0014 18.6 0.0 1.1 9.4 0.0 3.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain zinc_ribbon_10 PF10058.9 KER19201.1 - 0.039 13.7 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Mx_ML PF17536.2 KER19202.1 - 0.024 14.4 2.8 1.7 8.4 0.3 2.2 2 0 0 2 2 2 0 Matrix and Matrix long proteins N-terminal Marek_SORF3 PF07153.11 KER19202.1 - 0.11 11.8 0.7 8.2 5.7 0.1 2.1 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein Amdo_NSP PF12475.8 KER19202.1 - 0.99 9.5 9.8 13 5.9 0.0 4.0 4 0 0 4 4 4 0 Amdovirus non-structural protein Peptidase_M50 PF02163.22 KER19204.1 - 3.1e-21 75.8 0.0 4.3e-20 72.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 Band_3_cyto PF07565.13 KER19205.1 - 0.0022 17.8 0.0 0.0022 17.8 0.0 1.0 1 0 0 1 1 1 1 Band 3 cytoplasmic domain IFT57 PF10498.9 KER19206.1 - 2.9e-122 408.2 4.2 4.4e-121 404.3 4.2 1.9 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KER19206.1 - 0.011 15.8 0.3 0.032 14.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 KER19206.1 - 0.014 15.8 3.5 0.031 14.7 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KER19206.1 - 0.021 13.7 2.4 0.036 12.9 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KER19206.1 - 0.051 14.0 5.7 0.21 12.0 5.7 2.0 1 1 1 2 2 2 0 Fez1 PhaP_Bmeg PF09602.10 KER19206.1 - 0.068 13.1 0.4 0.25 11.3 0.4 1.9 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1043 PF06295.12 KER19206.1 - 0.073 13.1 0.3 0.46 10.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) IL11 PF07400.11 KER19206.1 - 0.081 12.6 0.4 0.21 11.2 0.4 1.7 1 0 0 1 1 1 0 Interleukin 11 ADIP PF11559.8 KER19206.1 - 0.1 12.7 4.6 0.32 11.1 0.5 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 KER19206.1 - 0.13 12.3 0.0 1.4 8.9 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helo_like_N PF17111.5 KER19206.1 - 0.18 11.2 2.1 2.2 7.6 0.4 2.3 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins GAS PF13851.6 KER19206.1 - 0.22 10.9 3.5 0.6 9.4 2.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 KER19206.1 - 0.24 11.4 1.1 0.96 9.5 0.5 2.0 1 1 1 2 2 2 0 Laminin Domain II HalX PF08663.10 KER19206.1 - 0.55 10.6 6.7 4.6 7.6 0.1 3.2 3 0 0 3 3 3 0 HalX domain ABC_tran_CTD PF16326.5 KER19206.1 - 0.72 10.2 4.2 2.7 8.3 1.4 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain FTA4 PF13093.6 KER19206.1 - 0.82 9.5 7.4 3.5 7.4 6.6 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Phage_Mu_Gam PF07352.12 KER19206.1 - 0.85 9.5 4.8 2.6 7.9 1.1 2.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Atg14 PF10186.9 KER19206.1 - 2 7.4 6.2 3.8 6.5 6.1 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RabGAP-TBC PF00566.18 KER19208.1 - 2.1e-13 50.5 0.1 3.1e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 KER19208.1 - 2e-06 28.3 0.0 3.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Exo_endo_phos_2 PF14529.6 KER19210.1 - 1e-07 31.8 0.2 1.6e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER19210.1 - 0.03 13.9 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Integrin_alpha2 PF08441.12 KER19212.1 - 5.1e-14 52.0 0.7 1.1e-12 47.6 0.0 2.9 3 1 1 4 4 4 1 Integrin alpha MCR_alpha PF02249.17 KER19212.1 - 0.019 15.4 0.0 5.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF4843 PF16132.5 KER19212.1 - 0.056 13.0 2.0 1.4 8.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4843) Integrin_alpha PF00357.20 KER19212.1 - 0.19 11.8 0.4 0.54 10.4 0.4 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region ATG16 PF08614.11 KER19213.1 - 0.0042 17.3 60.9 0.011 15.9 1.2 5.3 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KER19213.1 - 0.029 14.8 47.7 0.12 12.8 11.6 3.7 1 1 2 3 3 3 0 Fez1 Baculo_LEF-11 PF06385.12 KER19213.1 - 0.039 14.4 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 Baculovirus LEF-11 protein WXG100 PF06013.12 KER19213.1 - 0.045 14.0 11.0 5.9 7.2 0.0 5.2 4 1 0 4 4 4 0 Proteins of 100 residues with WXG NuiA PF07924.11 KER19213.1 - 0.096 13.1 4.0 8.2 6.8 1.4 2.8 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein GAS PF13851.6 KER19213.1 - 0.16 11.3 41.4 0.97 8.7 11.0 4.5 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3138 PF11336.8 KER19213.1 - 0.24 10.0 0.8 0.48 9.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF948 PF06103.11 KER19213.1 - 0.35 11.2 12.6 3.5 8.0 0.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.12 KER19213.1 - 0.72 9.8 0.0 0.72 9.8 0.0 5.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat ERM PF00769.19 KER19213.1 - 0.96 9.2 50.4 1.8 8.3 13.9 3.2 2 1 0 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.18 KER19213.1 - 5.8 7.2 10.7 22 5.4 0.4 4.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.8 KER19213.1 - 8.9 6.4 50.0 0.75 9.9 7.8 5.4 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Asp PF00026.23 KER19217.1 - 3.4e-10 39.9 0.0 3.8e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KER19217.1 - 0.057 14.1 0.0 0.088 13.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease GOLGA2L5 PF15070.6 KER19218.1 - 1.8e-05 23.7 1.3 1.8e-05 23.7 1.3 1.9 1 1 1 2 2 2 2 Putative golgin subfamily A member 2-like protein 5 Asp PF00026.23 KER19219.1 - 1.2e-29 103.7 0.1 1.5e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER19219.1 - 1.9e-08 34.7 1.1 1.4e-05 25.4 0.0 2.9 1 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER19219.1 - 0.089 13.4 0.0 0.68 10.6 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease CUB PF00431.20 KER19220.1 - 2.1e-62 208.3 6.4 3.2e-11 43.5 0.2 7.1 7 0 0 7 7 7 7 CUB domain CUB_2 PF02408.20 KER19220.1 - 0.0016 18.2 0.0 3.2 7.5 0.0 3.4 3 0 0 3 3 3 2 CUB-like domain Tubulin PF00091.25 KER19222.1 - 4e-50 170.7 0.0 6.8e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain BsuBI_PstI_RE_N PF17728.1 KER19222.1 - 2e-05 24.5 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 2 BsuBI/PstI restriction endonuclease HTH domain PARP_regulatory PF01358.18 KER19222.1 - 0.022 13.7 0.6 4.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Poly A polymerase regulatory subunit Gin PF10764.9 KER19222.1 - 0.045 13.7 0.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin NAD_binding_1 PF00175.21 KER19222.1 - 0.063 13.9 0.0 7.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2688 PF10892.8 KER19222.1 - 0.081 12.4 0.0 17 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Phage_DNA_bind PF02303.17 KER19222.1 - 0.098 12.9 0.1 23 5.3 0.0 2.3 2 0 0 2 2 2 0 Helix-destabilising protein DUF5370 PF17340.2 KER19222.1 - 0.13 12.1 0.0 25 4.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5370) GF_recep_IV PF14843.6 KER19222.1 - 0.19 11.5 0.3 17 5.2 0.1 2.2 2 0 0 2 2 2 0 Growth factor receptor domain IV Serpin PF00079.20 KER19223.1 - 4.9e-94 315.7 0.0 5.8e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.14 KER19223.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) His_Phos_2 PF00328.22 KER19226.1 - 6.4e-08 32.3 0.1 9.3e-08 31.8 0.1 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_C13 PF01650.18 KER19227.1 - 8.6e-58 195.8 2.5 1.9e-57 194.7 1.8 1.7 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER19227.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Peptidase_C25 PF01364.18 KER19227.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C25 DNA_photolyase PF00875.18 KER19228.1 - 1.5e-16 60.8 0.5 2.4e-15 56.9 0.5 2.3 1 1 0 1 1 1 1 DNA photolyase DEAD PF00270.29 KER19229.1 - 2.5e-50 170.7 0.0 4e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER19229.1 - 5.6e-31 107.2 0.0 2e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER19229.1 - 0.0047 17.0 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_19 PF00182.19 KER19230.1 - 1.5e-21 77.3 0.3 1.5e-20 74.1 0.3 2.1 1 1 0 1 1 1 1 Chitinase class I EB PF01683.18 KER19230.1 - 3.4 8.0 16.8 4.3 7.7 15.5 1.9 1 1 1 2 2 2 0 EB module AMMECR1 PF01871.17 KER19231.1 - 1.8e-15 57.0 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Peptidase_C13 PF01650.18 KER19234.1 - 7.6e-84 281.2 2.8 1e-83 280.8 2.8 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19234.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Aldo_ket_red PF00248.21 KER19235.1 - 1.7e-08 34.0 0.0 1.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KER19236.1 - 1.7e-11 43.9 0.1 2.2e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Exo_endo_phos_2 PF14529.6 KER19236.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Aldo_ket_red PF00248.21 KER19237.1 - 1.1e-36 126.6 0.0 1.4e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PIP5K PF01504.18 KER19238.1 - 2e-65 220.8 0.0 2.2e-64 217.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase KASH_CCD PF14662.6 KER19239.1 - 0.05 13.4 8.8 0.1 12.5 8.8 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YdfA_immunity PF12127.8 KER19239.1 - 0.053 12.6 1.8 0.09 11.8 1.8 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial Ephrin_rec_like PF07699.13 KER19239.1 - 0.058 13.2 3.9 0.13 12.0 3.9 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like Rdx PF10262.9 KER19239.1 - 0.072 13.3 0.3 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Rdx family Tup_N PF08581.10 KER19239.1 - 0.29 11.5 6.3 0.5 10.7 5.3 1.9 1 1 0 1 1 1 0 Tup N-terminal YgaB PF14182.6 KER19239.1 - 0.55 10.7 5.3 2.2 8.7 5.3 2.0 1 0 0 1 1 1 0 YgaB-like protein DUF724 PF05266.14 KER19239.1 - 0.9 9.3 6.2 1.5 8.6 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.14 KER19239.1 - 1.6 9.1 8.8 4.2 7.7 8.8 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MIP-T3_C PF17749.1 KER19239.1 - 1.8 8.5 7.7 0.49 10.4 3.1 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Atg14 PF10186.9 KER19239.1 - 2 7.4 7.9 3.5 6.6 7.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 KER19239.1 - 5 7.6 9.1 13 6.3 8.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ufd2P_core PF10408.9 KER19241.1 - 2.7e-160 535.0 0.4 4.5e-90 303.1 0.5 2.3 1 1 1 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 KER19241.1 - 2.3e-24 85.3 0.6 4.9e-24 84.3 0.6 1.6 1 0 0 1 1 1 1 U-box domain La PF05383.17 KER19242.1 - 9.8e-20 70.4 0.3 2.1e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 La domain SET PF00856.28 KER19242.1 - 4.2e-17 63.1 1.3 2.6e-16 60.5 0.2 2.9 2 0 0 2 2 2 1 SET domain RRM_3 PF08777.11 KER19242.1 - 2.5e-12 46.7 0.9 1.2e-10 41.3 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif preSET_CXC PF18264.1 KER19242.1 - 2.3e-10 40.8 14.7 2.3e-10 40.8 14.7 2.9 2 0 0 2 2 2 1 CXC domain RRM_1 PF00076.22 KER19242.1 - 3.3e-05 23.6 0.0 0.00094 19.0 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L27_N PF09060.10 KER19242.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 L27_N TCR PF03638.15 KER19242.1 - 9.5 6.6 32.5 1 9.7 13.7 2.9 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Anoctamin PF04547.12 KER19244.1 - 1.9e-84 284.1 4.5 2.6e-84 283.7 4.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel TctB PF07331.11 KER19244.1 - 0.21 11.8 15.8 0.058 13.7 0.5 3.9 2 1 2 4 4 4 0 Tripartite tricarboxylate transporter TctB family DUF2975 PF11188.8 KER19244.1 - 6.3 6.7 12.4 0.91 9.4 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) QVR PF17064.5 KER19247.1 - 0.0014 18.8 6.1 0.0026 18.0 6.1 1.4 1 1 0 1 1 1 1 Sleepless protein UPAR_LY6_2 PF16975.5 KER19247.1 - 0.068 13.4 2.7 0.13 12.5 2.7 1.5 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF5133 PF17196.4 KER19247.1 - 0.1 12.8 0.6 0.16 12.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) SIR2 PF02146.17 KER19249.1 - 1.9e-19 70.3 0.1 1.7e-11 44.4 0.0 3.0 3 1 0 3 3 3 2 Sir2 family HTH_IclR PF09339.10 KER19249.1 - 0.14 12.0 0.0 0.6 9.9 0.1 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Peptidase_C13 PF01650.18 KER19251.1 - 2.4e-76 256.6 2.8 3e-76 256.3 2.8 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19251.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Caspase domain MBOAT PF03062.19 KER19252.1 - 1.8e-26 93.3 15.7 2.4e-26 92.9 15.7 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MtrA PF04208.14 KER19254.1 - 0.019 14.6 0.0 0.14 11.8 0.0 1.8 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A SLBP_RNA_bind PF15247.6 KER19254.1 - 0.048 13.8 0.2 5.6 7.2 0.1 2.1 1 1 1 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Tim44 PF04280.15 KER19254.1 - 0.11 12.6 0.0 7.3 6.7 0.0 2.0 2 0 0 2 2 2 0 Tim44-like domain YqcI_YcgG PF08892.11 KER19254.1 - 0.16 11.8 0.1 11 5.8 0.0 2.0 1 1 1 2 2 2 0 YqcI/YcgG family RNA_pol_Rpb1_2 PF00623.20 KER19256.1 - 2.4e-58 197.0 0.1 6.4e-58 195.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 KER19256.1 - 1e-57 195.6 0.0 1.6e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KER19256.1 - 6.1e-34 117.2 0.0 1.8e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KER19256.1 - 7.9e-17 61.2 0.0 2.4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 KER19256.1 - 2.1e-15 56.9 0.0 3.1e-14 53.0 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Biopterin_H PF00351.21 KER19257.1 - 8.8e-162 537.8 0.1 1.1e-161 537.4 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Fasciclin PF02469.22 KER19261.1 - 1.6e-28 99.4 0.0 9.3e-10 38.8 0.0 4.4 4 1 0 4 4 4 4 Fasciclin domain FYVE_2 PF02318.16 KER19263.1 - 0.043 14.0 0.9 0.11 12.7 0.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger PRKCSH PF07915.13 KER19264.1 - 4.8e-13 49.9 0.5 1.3e-12 48.5 0.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KER19264.1 - 1.2e-06 28.3 0.1 2.3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein RP-C_C PF11800.8 KER19264.1 - 0.17 12.0 0.8 2.8 8.0 0.4 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF4611 PF15387.6 KER19264.1 - 0.55 10.5 6.2 1.1 9.5 5.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Phage_sheath_1 PF04984.14 KER19265.1 - 0.095 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain RabGAP-TBC PF00566.18 KER19266.1 - 2.9e-52 177.5 0.0 4.8e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Exotox-A_target PF09102.10 KER19266.1 - 0.052 13.5 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Exotoxin A, targeting bZIP_1 PF00170.21 KER19268.1 - 1.3e-09 38.0 16.2 2.3e-09 37.2 16.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor APG6_N PF17675.1 KER19268.1 - 0.00053 20.5 2.6 0.00084 19.9 2.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region bZIP_2 PF07716.15 KER19268.1 - 0.0014 18.7 15.7 0.0014 18.7 14.5 1.6 1 1 1 2 2 2 1 Basic region leucine zipper HOOK PF05622.12 KER19268.1 - 0.0076 14.5 5.0 0.011 14.0 5.0 1.1 1 0 0 1 1 1 1 HOOK protein bZIP_Maf PF03131.17 KER19268.1 - 0.0095 16.4 9.2 0.022 15.3 9.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor FPP PF05911.11 KER19268.1 - 0.15 10.2 3.2 0.22 9.7 3.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 KER19268.1 - 0.27 10.5 2.8 0.42 9.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 KER19268.1 - 0.7 10.4 7.6 1.7 9.2 7.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB ADIP PF11559.8 KER19268.1 - 1.2 9.2 8.8 2.4 8.3 8.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EGF PF00008.27 KER19270.1 - 1.4e-51 172.3 177.6 8.9e-08 32.3 9.8 14.2 13 1 0 13 13 13 11 EGF-like domain hEGF PF12661.7 KER19270.1 - 1e-32 111.6 153.0 1.3e-05 25.7 8.7 14.8 13 2 0 13 13 13 10 Human growth factor-like EGF EGF_2 PF07974.13 KER19270.1 - 6.8e-20 71.1 194.7 0.0014 19.0 11.3 13.6 12 1 1 13 13 13 10 EGF-like domain EGF_CA PF07645.15 KER19270.1 - 2e-17 63.1 52.1 3.9e-08 33.4 6.2 12.7 8 3 6 14 14 14 5 Calcium-binding EGF domain EGF_3 PF12947.7 KER19270.1 - 0.0047 17.1 4.3 0.0047 17.1 4.3 13.3 12 1 1 13 13 13 8 EGF domain FXa_inhibition PF14670.6 KER19270.1 - 0.0069 16.6 5.0 0.0069 16.6 5.0 13.3 7 4 5 12 12 12 5 Coagulation Factor Xa inhibitory site EF1G PF00647.19 KER19272.1 - 7.9e-32 109.5 0.0 1.6e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KER19272.1 - 1.7e-12 47.4 0.0 4.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER19272.1 - 4.6e-11 42.9 0.0 1.5e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KER19272.1 - 1.5e-09 37.9 0.0 6.2e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER19272.1 - 1.4e-08 34.7 0.2 5e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KER19272.1 - 7.3e-08 32.7 0.0 2.7e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER19272.1 - 0.00017 21.8 1.0 0.0014 18.9 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KER19272.1 - 0.00082 19.1 0.6 0.0023 17.7 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain DUF2520 PF10728.9 KER19272.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) MFS_1 PF07690.16 KER19273.1 - 1.3e-40 139.5 31.1 1.3e-40 139.5 31.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KER19273.1 - 2.7e-08 33.1 4.8 2.7e-08 33.1 4.8 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KER19273.1 - 0.021 13.2 19.2 0.29 9.5 19.2 2.3 1 1 0 1 1 1 0 Transmembrane secretion effector PNP_UDP_1 PF01048.20 KER19274.1 - 2.2e-32 112.2 0.0 2.9e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.16 KER19275.1 - 3.4e-11 42.7 6.7 3.4e-11 42.7 6.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KER19275.1 - 2.5e-10 39.8 6.0 2.5e-10 39.8 6.0 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5326 PF17260.2 KER19275.1 - 0.057 13.6 3.7 0.15 12.2 3.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5326) GDI PF00996.18 KER19276.1 - 3.9e-14 52.0 0.0 1.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor SH3-WW_linker PF16618.5 KER19276.1 - 0.24 11.9 2.1 12 6.3 0.2 2.2 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 LIM PF00412.22 KER19277.1 - 1.5e-11 44.3 6.5 2.9e-11 43.4 6.5 1.5 1 0 0 1 1 1 1 LIM domain Homeodomain PF00046.29 KER19278.1 - 9.4e-19 67.0 1.7 1.9e-18 66.0 1.7 1.5 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KER19278.1 - 5.9e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KER19278.1 - 0.00031 20.6 0.1 0.00031 20.6 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain CENP-B_N PF04218.13 KER19278.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF4707 PF15806.5 KER19280.1 - 0.08 11.9 0.5 9.4 5.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4707) RRM_1 PF00076.22 KER19281.1 - 1.5e-13 50.3 0.1 2.6e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4817 PF16087.5 KER19281.1 - 2.1e-09 37.0 0.0 1.7e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) Curto_V3 PF07436.11 KER19282.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Curtovirus V3 protein Peptidase_C13 PF01650.18 KER19284.1 - 7e-40 137.1 7.0 1.2e-22 80.7 0.8 2.0 1 1 1 2 2 2 2 Peptidase C13 family Ribonuclease_T2 PF00445.18 KER19284.1 - 0.051 13.8 0.1 10 6.3 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease T2 family Sulfotransfer_3 PF13469.6 KER19284.1 - 0.1 12.9 0.0 12 6.2 0.0 2.1 2 0 0 2 2 2 0 Sulfotransferase family VirDNA-topo-I_N PF09266.10 KER19284.1 - 2.9 8.1 7.5 13 6.0 0.1 3.4 4 0 0 4 4 4 0 Viral DNA topoisomerase I, N-terminal BDHCT PF08072.11 KER19286.1 - 0.078 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 BDHCT (NUC031) domain SF3b1 PF08920.10 KER19292.1 - 9.5e-39 132.6 47.5 2e-37 128.3 15.0 5.7 2 2 2 4 4 4 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KER19292.1 - 1.5e-10 41.3 2.2 0.29 11.5 0.0 7.5 5 2 2 7 7 7 2 HEAT repeats HEAT PF02985.22 KER19292.1 - 1.5e-09 37.3 4.5 0.69 10.3 0.1 7.9 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 KER19292.1 - 4.8e-07 30.1 8.3 0.83 10.2 0.0 7.6 9 1 1 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KER19292.1 - 4.8e-06 27.1 1.4 1.5 9.5 0.0 4.9 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KER19292.1 - 1.5e-05 25.1 6.8 2.5 8.1 0.0 6.9 6 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KER19292.1 - 0.00032 20.3 0.8 3.8 7.0 0.1 3.4 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 KER19292.1 - 0.0004 20.3 3.8 0.56 10.1 0.1 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) UME PF08064.13 KER19292.1 - 0.00043 20.2 0.9 4.8 7.1 0.1 5.5 6 1 0 6 6 6 1 UME (NUC010) domain IFRD PF05004.13 KER19292.1 - 0.0012 18.0 0.3 1.1 8.3 0.0 3.4 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 KER19292.1 - 0.0078 15.9 0.5 2.3 7.8 0.0 4.2 4 2 0 5 5 5 1 NUC173 domain Adaptin_N PF01602.20 KER19292.1 - 0.018 13.6 2.3 0.17 10.4 1.9 2.8 1 1 0 1 1 1 0 Adaptin N terminal region TIP120 PF08623.10 KER19292.1 - 0.045 13.5 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DRIM PF07539.12 KER19292.1 - 0.12 10.7 0.2 18 3.5 0.0 3.2 2 1 0 3 3 3 0 Down-regulated in metastasis DNA_pol_phi PF04931.13 KER19292.1 - 0.17 9.9 0.0 6.5 4.7 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi DUF688 PF05097.12 KER19292.1 - 0.2 10.8 1.7 0.3 10.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Hydrolase_4 PF12146.8 KER19293.1 - 1.1e-15 57.6 0.2 4.8e-11 42.4 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KER19293.1 - 1.1e-10 41.6 0.0 2e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER19293.1 - 1.4e-08 35.7 0.1 2.8e-06 28.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 KER19293.1 - 9.2e-06 24.8 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KER19293.1 - 0.0016 18.0 0.0 0.017 14.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KER19293.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 KER19293.1 - 0.099 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Carb_anhydrase PF00194.21 KER19297.1 - 9.7e-73 244.8 0.2 1.2e-72 244.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KER19298.1 - 4.9e-74 249.1 0.5 6.3e-74 248.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KER19299.1 - 3.5e-63 213.5 0.5 4.2e-63 213.2 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase BssS PF13991.6 KER19299.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BssS protein family Carb_anhydrase PF00194.21 KER19300.1 - 6.5e-68 229.0 0.3 7.2e-68 228.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Neur_chan_LBD PF02931.23 KER19301.1 - 5e-53 179.8 2.5 7.5e-53 179.2 2.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER19301.1 - 1.1e-33 117.2 1.0 4.9e-32 111.9 1.0 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YpmT PF17431.2 KER19301.1 - 0.16 12.0 0.2 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized YmpT-like zf-B_box PF00643.24 KER19302.1 - 2e-07 31.1 6.9 2.1e-05 24.6 1.7 5.3 5 1 0 5 5 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 KER19302.1 - 2.2e-07 30.7 2.0 2.2e-07 30.7 2.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER19302.1 - 2.5e-05 24.1 4.8 2.5e-05 24.1 4.8 5.0 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER19302.1 - 0.00023 21.0 5.2 0.00023 21.0 5.2 4.2 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KER19302.1 - 0.00085 19.4 3.8 0.00085 19.4 3.8 4.4 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KER19302.1 - 0.0055 16.5 5.9 0.0055 16.5 5.9 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER19302.1 - 0.019 15.3 4.0 0.019 15.3 4.0 4.9 5 1 0 5 5 4 0 Ring finger domain Fructosamin_kin PF03881.14 KER19302.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Golgin_A5 PF09787.9 KER19302.1 - 0.49 9.8 4.6 0.18 11.2 1.5 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 HAUS6_N PF14661.6 KER19302.1 - 0.82 9.2 4.4 0.49 9.9 0.8 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus IBR PF01485.21 KER19302.1 - 0.89 9.8 20.8 0.44 10.8 0.7 4.5 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain Cys_rich_CPCC PF14206.6 KER19302.1 - 1.7 8.5 7.4 0.29 11.0 0.2 3.1 4 0 0 4 4 4 0 Cysteine-rich CPCC zf-Sec23_Sec24 PF04810.15 KER19302.1 - 1.8 8.7 8.6 1.2 9.3 0.7 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Cnd1 PF12717.7 KER19303.1 - 0.00073 19.6 6.2 1.2 9.1 0.1 5.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KER19303.1 - 0.0089 16.2 4.6 2.1 8.8 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KER19303.1 - 0.011 16.1 0.4 0.25 11.8 0.4 3.2 2 0 0 2 2 2 0 HEAT repeats Adaptin_N PF01602.20 KER19303.1 - 0.039 12.5 6.9 0.11 11.1 3.2 3.0 2 1 0 2 2 2 0 Adaptin N terminal region Nif11 PF07862.11 KER19303.1 - 0.11 12.8 0.1 0.34 11.2 0.1 1.9 1 0 0 1 1 1 0 Nif11 domain EMC3_TMCO1 PF01956.16 KER19304.1 - 2.4e-40 138.0 0.1 4.7e-40 137.1 0.0 1.5 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like D123 PF07065.14 KER19305.1 - 1.3e-53 182.2 2.0 3.6e-51 174.1 2.0 2.5 1 1 0 1 1 1 1 D123 DnaJ PF00226.31 KER19306.1 - 1.6e-20 73.0 0.6 1.6e-20 73.0 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain EGF_CA PF07645.15 KER19307.1 - 1.2e-05 25.4 7.6 1.2e-05 25.4 7.6 3.1 2 0 0 2 2 2 1 Calcium-binding EGF domain TNFR_c6 PF00020.18 KER19307.1 - 1.6e-05 25.2 8.9 1.6e-05 25.2 8.9 5.1 2 1 2 4 4 4 2 TNFR/NGFR cysteine-rich region hEGF PF12661.7 KER19307.1 - 0.0087 16.7 4.0 0.0087 16.7 4.0 2.8 2 0 0 2 2 2 1 Human growth factor-like EGF Varsurf_PPLC PF03490.13 KER19308.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.9 1 1 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Kunitz_BPTI PF00014.23 KER19310.1 - 1.1e-06 28.8 10.2 1.6e-06 28.3 10.2 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF2475 PF10629.9 KER19310.1 - 0.056 13.7 0.6 0.082 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) DUF4494 PF14902.6 KER19311.1 - 0.06 13.2 3.1 6.3 6.6 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4494) HEPN_AbiA_CTD PF18732.1 KER19311.1 - 0.27 11.2 0.0 0.27 11.2 0.0 4.2 5 0 0 5 5 5 0 HEPN like, Abia C-terminal domain TTKRSYEDQ PF10212.9 KER19312.1 - 7.4e-05 21.9 1.6 8.5e-05 21.7 1.6 1.0 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein MINDY_DUB PF04424.13 KER19312.1 - 0.0009 19.3 0.2 0.0015 18.5 0.2 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase ATG16 PF08614.11 KER19312.1 - 0.0043 17.3 2.2 0.86 9.8 0.1 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF262 PF03235.14 KER19312.1 - 0.013 15.6 0.3 0.017 15.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF5327 PF17261.2 KER19312.1 - 0.042 14.6 0.1 0.075 13.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) IL10 PF00726.17 KER19312.1 - 0.079 12.5 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Interleukin 10 tRNA-synt_1 PF00133.22 KER19313.1 - 3.3e-157 524.3 0.0 2.8e-156 521.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Glyco_hydro_85 PF03644.13 KER19313.1 - 4e-44 151.2 0.0 1.8e-27 96.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 85 tRNA-synt_1g PF09334.11 KER19313.1 - 6.6e-16 58.0 0.0 0.00013 20.9 0.0 4.3 4 0 0 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KER19313.1 - 8.7e-15 55.0 0.1 4.1e-14 52.8 0.1 2.2 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA Ribosomal_L17 PF01196.19 KER19313.1 - 0.0012 19.7 0.0 0.0027 18.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 tRNA-synt_1_2 PF13603.6 KER19313.1 - 0.0025 17.4 0.0 0.014 14.9 0.0 2.0 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Snapin_Pallidin PF14712.6 KER19313.1 - 0.091 13.2 3.5 0.27 11.7 3.5 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Lactococcin PF04369.13 KER19314.1 - 0.053 13.7 0.2 0.076 13.2 0.2 1.3 1 0 0 1 1 1 0 Lactococcin-like family Peptidase_C13 PF01650.18 KER19316.1 - 6.7e-49 166.7 4.3 2.6e-39 135.3 1.1 2.0 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C13 PF01650.18 KER19317.1 - 3.7e-34 118.4 1.4 3.9e-29 101.9 0.1 2.0 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER19317.1 - 0.026 14.5 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Peptidase_C25 PF01364.18 KER19317.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.2 1 1 0 1 1 1 0 Peptidase family C25 DUF3386 PF11866.8 KER19319.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) RTC PF01137.21 KER19321.1 - 2.9e-62 209.8 0.0 3.7e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KER19321.1 - 7e-05 23.3 0.0 0.00021 21.8 0.0 1.7 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Med10 PF09748.9 KER19323.1 - 2.4e-31 108.2 0.1 2.9e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Syntaxin PF00804.25 KER19323.1 - 0.013 15.2 0.8 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Syntaxin DUF601 PF04642.12 KER19323.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Tmemb_55A PF09788.9 KER19324.1 - 1e-31 109.9 5.3 2.4e-26 92.3 1.2 2.0 2 0 0 2 2 2 2 Transmembrane protein 55A Mu-like_Com PF10122.9 KER19324.1 - 0.18 11.3 0.2 0.18 11.3 0.2 2.5 2 1 1 3 3 3 0 Mu-like prophage protein Com DZR PF12773.7 KER19324.1 - 0.37 10.8 15.8 0.26 11.3 2.9 3.1 3 0 0 3 3 3 0 Double zinc ribbon IBR PF01485.21 KER19324.1 - 0.43 10.8 6.9 0.48 10.7 0.1 3.4 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 KER19324.1 - 6.4 7.0 11.6 4.8 7.4 0.4 2.9 3 0 0 3 3 3 0 Zinc ribbon domain LMBR1 PF04791.16 KER19325.1 - 4e-40 138.2 8.4 4.8e-40 137.9 8.4 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Mannosyl_trans2 PF04188.13 KER19325.1 - 0.034 13.5 1.3 1.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Mannosyltransferase (PIG-V) DUF1656 PF07869.12 KER19325.1 - 0.051 13.6 2.5 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Birna_VP3 PF01767.16 KER19325.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein RRM_1 PF00076.22 KER19327.1 - 1.9e-15 56.4 0.7 3.4e-15 55.6 0.7 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER19327.1 - 0.0033 17.5 0.0 0.013 15.6 0.1 2.0 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KER19327.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KER19327.1 - 0.15 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nramp PF01566.18 KER19328.1 - 3.8e-116 388.0 12.8 3.8e-116 388.0 12.8 1.9 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein CUB PF00431.20 KER19330.1 - 6.5e-22 78.0 0.0 7.7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 KER19331.1 - 2.2e-10 40.8 0.0 5.1e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 CUB domain DUF3549 PF12069.8 KER19333.1 - 0.058 12.4 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF3549 PF12069.8 KER19336.1 - 0.058 12.4 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF2981 PF11200.8 KER19338.1 - 0.48 10.1 2.1 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) Peptidase_C13 PF01650.18 KER19340.1 - 2.8e-18 66.4 0.4 3.5e-18 66.1 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER19341.1 - 3.2e-90 302.1 2.9 1.9e-82 276.6 2.1 2.1 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER19341.1 - 1.1e-05 25.5 0.1 1.7e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER19341.1 - 0.0023 17.2 0.5 0.0038 16.5 0.5 1.2 1 0 0 1 1 1 1 Peptidase family C25 rve PF00665.26 KER19343.1 - 2.3e-12 47.2 0.0 2.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Dynein_light PF01221.18 KER19345.1 - 7.7e-40 135.1 0.8 8.5e-40 135.0 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 KER19345.1 - 0.03 14.3 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Dynein_light PF01221.18 KER19346.1 - 4.1e-41 139.2 0.7 4.8e-41 139.0 0.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 EFhand_Ca_insen PF08726.10 KER19346.1 - 0.0045 17.1 1.1 0.0074 16.4 1.1 1.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Dynein_light PF01221.18 KER19347.1 - 3.8e-28 97.7 0.5 4.3e-28 97.5 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 OGFr_N PF04664.13 KER19347.1 - 0.015 14.8 0.2 0.026 14.1 0.1 1.4 2 0 0 2 2 2 0 Opioid growth factor receptor (OGFr) conserved region AAA_lid_7 PF17867.1 KER19347.1 - 0.016 15.4 0.1 0.024 14.8 0.1 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain WD40 PF00400.32 KER19353.1 - 2.6e-41 138.8 15.1 6.3e-07 30.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER19353.1 - 3.7e-11 43.2 0.1 0.62 10.4 0.0 5.2 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER19353.1 - 1.2e-05 24.5 0.1 0.86 8.5 0.0 3.9 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KER19353.1 - 0.0013 17.5 1.3 6.3 5.3 0.0 3.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KER19353.1 - 0.084 12.8 3.5 16 5.6 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KER19353.1 - 0.14 12.7 0.3 52 4.5 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain FAT PF02259.23 KER19354.1 - 1.6e-09 37.4 0.9 3.3e-06 26.6 0.0 3.8 3 1 1 4 4 4 2 FAT domain DnaJ PF00226.31 KER19357.1 - 3.3e-13 49.5 0.1 5e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 KER19357.1 - 0.13 10.7 4.6 0.11 11.0 4.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TMEM52 PF14979.6 KER19357.1 - 0.19 11.6 9.2 0.25 11.3 9.2 1.2 1 0 0 1 1 1 0 Transmembrane 52 LMF1 PF06762.14 KER19358.1 - 1.6e-105 353.8 7.9 2.2e-103 346.8 1.8 2.1 2 0 0 2 2 2 2 Lipase maturation factor MBOAT_2 PF13813.6 KER19358.1 - 0.013 15.8 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Glyoxalase_4 PF13669.6 KER19359.1 - 3.6e-21 75.5 0.0 4.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KER19359.1 - 5.4e-12 46.0 0.0 6.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KER19359.1 - 4.7e-06 26.8 0.0 4.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KER19359.1 - 0.019 15.7 0.0 0.029 15.2 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KER19359.1 - 0.041 13.8 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain TRC8_N PF13705.6 KER19361.1 - 8.5e-13 48.0 28.9 2.7e-11 43.1 2.0 3.9 3 1 0 3 3 3 2 TRC8 N-terminal domain zf-RING_2 PF13639.6 KER19361.1 - 2.4e-09 37.4 7.9 2.4e-09 37.4 7.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KER19361.1 - 6.1e-08 32.4 6.3 1.9e-07 30.8 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER19361.1 - 1e-07 32.1 4.1 3e-07 30.6 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER19361.1 - 7e-07 29.2 1.6 1.2e-06 28.4 0.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER19361.1 - 4e-06 26.6 4.9 1.6e-05 24.7 4.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER19361.1 - 1.4e-05 25.0 5.6 5.8e-05 23.0 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER19361.1 - 4.5e-05 23.2 3.3 0.00017 21.4 3.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KER19361.1 - 0.00014 21.5 1.2 0.00014 21.5 1.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 KER19361.1 - 0.0049 17.0 2.9 0.019 15.2 2.9 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KER19361.1 - 0.013 15.5 2.1 0.013 15.5 2.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KER19361.1 - 0.035 14.0 7.0 1.7 8.5 7.3 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KER19361.1 - 1.2 9.3 4.5 2.7 8.2 4.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 KER19361.1 - 2 8.6 7.9 1 9.6 3.5 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Coatomer_E PF04733.14 KER19362.1 - 1.5e-48 165.7 1.3 1.6e-48 165.6 1.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 KER19362.1 - 6.4e-08 32.8 0.7 4.6e-07 30.0 1.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER19362.1 - 9.2e-06 26.1 3.1 1.4e-05 25.5 0.8 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER19362.1 - 0.00049 19.9 1.5 0.13 12.2 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER19362.1 - 0.008 16.2 2.2 0.09 12.9 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER19362.1 - 0.026 15.2 1.5 1.2 10.0 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER19362.1 - 0.033 14.4 0.3 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER19362.1 - 0.047 14.5 0.7 1.9 9.5 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KER19362.1 - 0.055 14.1 0.1 0.41 11.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER19362.1 - 0.081 13.0 0.5 0.93 9.7 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER19362.1 - 0.76 9.7 0.0 0.76 9.7 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Toxin_TOLIP PF00087.21 KER19363.1 - 0.026 14.8 14.2 0.048 13.9 14.1 1.6 1 1 0 1 1 1 0 Snake toxin and toxin-like protein Ribosomal_L16 PF00252.18 KER19366.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PI3_PI4_kinase PF00454.27 KER19368.1 - 3.2e-48 164.7 0.0 3.3e-47 161.4 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KER19368.1 - 2.1e-33 115.3 0.1 9e-21 74.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.16 KER19368.1 - 7.1e-19 67.3 0.4 1.8e-18 66.0 0.1 1.9 2 0 0 2 2 2 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.24 KER19368.1 - 4.9e-06 26.5 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KER19368.1 - 1.4e-05 25.2 0.0 4.9e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain RVT_1 PF00078.27 KER19368.1 - 0.0019 17.7 0.0 0.006 16.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cucumo_2B PF03263.13 KER19369.1 - 0.046 14.2 0.1 0.08 13.4 0.1 1.3 1 0 0 1 1 1 0 Cucumovirus protein 2B Methyltransf_PK PF05891.12 KER19370.1 - 5.5e-72 241.8 0.0 1e-71 241.0 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KER19370.1 - 0.00013 22.6 0.0 0.00048 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER19370.1 - 0.00029 21.4 0.0 0.00087 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KER19370.1 - 0.0011 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Nucleoporin_FG PF13634.6 KER19370.1 - 0.0074 17.1 106.5 0.083 13.7 8.3 6.9 2 2 3 5 5 5 4 Nucleoporin FG repeat region Methyltransf_23 PF13489.6 KER19370.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 KER19372.1 - 1.9e-17 63.7 0.0 2.4e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER19372.1 - 0.00065 19.5 0.1 0.0014 18.4 0.1 1.7 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER19373.1 - 0.0077 15.7 0.0 0.0085 15.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_C13 PF01650.18 KER19375.1 - 3.4e-92 308.6 1.1 4.8e-92 308.1 1.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family CNOT1_TTP_bind PF16417.5 KER19375.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain EndoU_bacteria PF14436.6 KER19376.1 - 0.11 12.9 0.1 2.6 8.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial EndoU nuclease CSTF2_hinge PF14327.6 KER19377.1 - 2.2e-08 34.4 0.6 0.01 16.3 0.1 2.2 2 0 0 2 2 2 2 Hinge domain of cleavage stimulation factor subunit 2 DUF5634_N PF18672.1 KER19377.1 - 0.068 12.9 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5634) RbpA PF13397.6 KER19377.1 - 0.29 11.8 2.3 34 5.1 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase-binding protein Pkinase PF00069.25 KER19378.1 - 2.9e-61 207.1 0.0 7.2e-34 117.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER19378.1 - 9.5e-37 126.7 0.0 7.8e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KER19378.1 - 2e-07 30.6 0.0 4.8e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER19378.1 - 6e-05 22.0 0.0 0.00037 19.4 0.0 2.0 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER19378.1 - 9.6e-05 21.8 0.0 0.041 13.2 0.0 2.6 3 0 0 3 3 3 2 Kinase-like LRR_6 PF13516.6 KER19379.1 - 1.3e-25 87.2 16.6 0.0005 19.9 0.1 9.4 9 0 0 9 9 9 8 Leucine Rich repeat LRR_1 PF00560.33 KER19379.1 - 2.1e-07 30.6 9.2 18 6.4 0.0 8.7 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 KER19379.1 - 0.0011 19.3 22.4 1.2 9.7 0.4 6.5 5 3 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER19379.1 - 0.035 13.9 19.9 4.1 7.2 1.0 7.2 3 2 3 6 6 6 0 Leucine rich repeat EF-hand_7 PF13499.6 KER19379.1 - 0.046 14.2 0.2 0.37 11.3 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain pair Transket_pyr PF02779.24 KER19380.1 - 1.4e-44 151.9 0.0 2.2e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KER19380.1 - 3.1e-40 136.9 0.0 5.9e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KER19380.1 - 0.00042 20.6 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II CAP PF00188.26 KER19381.1 - 9.2e-21 75.0 0.0 3.6e-20 73.1 0.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CDP-OH_P_transf PF01066.21 KER19382.1 - 1.1e-07 32.5 0.1 1.1e-07 32.5 0.1 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase CLP1_P PF16575.5 KER19383.1 - 3e-40 138.0 0.0 6.5e-40 136.9 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KER19383.1 - 8.4e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KER19383.1 - 1.3e-20 73.4 0.0 3.7e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 KER19383.1 - 0.0017 18.7 0.0 0.0035 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KER19383.1 - 0.0066 16.5 0.0 0.0086 16.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KER19383.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KER19383.1 - 0.026 14.3 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KER19383.1 - 0.028 14.7 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KER19383.1 - 0.043 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein KTI12 PF08433.10 KER19383.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 KER19383.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 KER19383.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 KER19383.1 - 0.14 12.4 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER19384.1 - 2.8e-49 167.1 0.0 7.6e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KER19384.1 - 5.7e-28 98.3 11.4 9.7e-28 97.6 11.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KER19384.1 - 1.3e-11 44.4 0.1 0.0033 16.9 0.0 4.7 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KER19384.1 - 3.3e-07 30.4 0.0 0.0029 17.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KER19384.1 - 1.5e-06 28.3 0.3 0.17 11.7 0.0 3.6 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KER19384.1 - 7e-06 26.5 0.1 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KER19384.1 - 3.6e-05 24.1 0.1 0.5 10.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KER19384.1 - 4.2e-05 24.1 0.1 0.087 13.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KER19384.1 - 5.4e-05 23.1 1.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KER19384.1 - 0.00088 19.4 1.9 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 KER19384.1 - 0.0012 18.5 1.6 0.43 10.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KER19384.1 - 0.0039 16.4 0.1 0.13 11.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KER19384.1 - 0.0049 16.2 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 KER19384.1 - 0.0054 16.8 0.6 0.37 10.8 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 KER19384.1 - 0.0073 16.1 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KER19384.1 - 0.0088 15.3 0.3 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 KER19384.1 - 0.022 14.3 0.1 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KER19384.1 - 0.028 14.6 0.6 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KER19384.1 - 0.029 14.1 0.0 1.5 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KER19384.1 - 0.034 14.7 0.0 5.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF2071 PF09844.9 KER19384.1 - 0.04 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) NACHT PF05729.12 KER19384.1 - 0.052 13.5 0.8 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 KER19384.1 - 0.064 13.7 0.0 3.5 8.1 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KER19384.1 - 0.077 12.0 0.0 6.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 KER19384.1 - 0.077 11.8 0.9 0.64 8.7 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_33 PF13671.6 KER19384.1 - 0.09 12.9 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KER19384.1 - 0.093 12.3 1.3 11 5.6 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KER19384.1 - 0.11 12.9 0.1 20 5.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 KER19384.1 - 0.11 12.2 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 KER19384.1 - 0.14 11.1 0.4 0.4 9.7 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_PrkA PF08298.11 KER19384.1 - 0.27 10.1 0.3 4.9 6.0 0.1 2.2 2 0 0 2 2 2 0 PrkA AAA domain DUF4064 PF13273.6 KER19384.1 - 2.6 8.4 5.5 4.4 7.6 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) MAS20 PF02064.15 KER19385.1 - 0.028 14.5 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 MAS20 protein import receptor zf-LITAF-like PF10601.9 KER19386.1 - 0.096 13.0 3.1 1 9.7 3.1 2.0 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain MMS1_N PF10433.9 KER19387.1 - 4e-168 560.1 0.0 6.6e-168 559.3 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KER19387.1 - 4e-78 263.0 0.0 1.5e-77 261.1 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region ATP-synt_Z PF16594.5 KER19388.1 - 0.12 11.8 0.4 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated Exo70 PF03081.15 KER19389.1 - 2.3e-54 184.9 2.8 2.3e-54 184.9 2.8 2.4 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Dus PF01207.17 KER19389.1 - 1.6e-36 126.0 1.6 2.5e-16 59.7 0.1 4.3 4 0 0 4 4 4 3 Dihydrouridine synthase (Dus) RVT_1 PF00078.27 KER19389.1 - 7.5e-12 45.2 0.0 2.5e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec34 PF04136.15 KER19389.1 - 0.36 10.7 5.3 1.2 9.0 5.3 1.9 1 0 0 1 1 1 0 Sec34-like family GrpE PF01025.19 KER19389.1 - 1.4 8.5 5.7 0.26 10.9 0.8 2.3 3 0 0 3 3 3 0 GrpE Peptidase_C13 PF01650.18 KER19391.1 - 1e-72 244.7 5.4 1.3e-41 142.8 0.1 2.2 1 1 1 2 2 2 2 Peptidase C13 family Desulfoferrod_N PF06397.12 KER19392.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Asp PF00026.23 KER19394.1 - 3.9e-31 108.6 0.0 1e-18 67.8 0.0 2.0 1 1 0 2 2 2 2 Eukaryotic aspartyl protease RAG2_PHD PF13341.6 KER19394.1 - 0.0011 19.0 0.3 1.7 8.8 0.1 2.4 2 0 0 2 2 2 2 RAG2 PHD domain Asp PF00026.23 KER19395.1 - 0.0045 16.5 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 KER19396.1 - 2e-08 34.1 0.0 3.8e-08 33.1 0.0 1.3 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TIP41 PF04176.13 KER19397.1 - 1.4e-52 177.7 0.0 2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family PufQ PF05398.11 KER19397.1 - 0.15 12.2 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 PufQ cytochrome subunit Peptidase_C13 PF01650.18 KER19398.1 - 1.7e-51 175.2 5.0 1.1e-38 133.3 0.1 3.3 3 0 0 3 3 3 3 Peptidase C13 family Peptidase_C14 PF00656.22 KER19398.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER19398.1 - 0.18 11.0 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Peptidase family C25 tRNA-synt_1b PF00579.25 KER19399.1 - 9.7e-45 153.1 0.0 1.2e-30 106.8 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Asp PF00026.23 KER19400.1 - 1.1e-26 94.1 0.0 1.3e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER19400.1 - 0.026 14.3 0.0 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal RAD51_interact PF15696.5 KER19401.1 - 1.4e-07 31.5 1.0 3.6e-07 30.2 1.0 1.8 1 0 0 1 1 1 1 RAD51 interacting motif Cation_ATPase_C PF00689.21 KER19402.1 - 6.8e-42 143.2 7.4 6.8e-42 143.2 7.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KER19402.1 - 2.3e-18 66.1 0.0 4.6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KER19402.1 - 4.1e-14 53.4 0.8 3.6e-12 47.0 0.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KER19402.1 - 2.1e-09 37.1 7.5 6.6e-09 35.5 0.2 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KER19402.1 - 5.4e-07 29.6 0.3 6.4e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 KER19402.1 - 6.4e-07 29.7 3.4 9.2e-05 22.8 2.1 2.8 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal DUF2207 PF09972.9 KER19402.1 - 0.37 9.5 2.0 1.4 7.6 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NADPH_Ox PF08414.10 KER19403.1 - 0.0092 16.3 1.3 0.33 11.3 0.1 2.3 1 1 1 2 2 2 1 Respiratory burst NADPH oxidase HTH_53 PF18606.1 KER19403.1 - 0.024 14.3 0.0 9.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain NPM1-C PF16276.5 KER19403.1 - 0.042 13.8 1.0 0.096 12.7 0.2 1.9 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain DUF4107 PF13389.6 KER19403.1 - 0.1 12.7 1.2 8 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Apolipoprotein PF01442.18 KER19408.1 - 4.2e-07 30.0 13.4 1.6e-06 28.1 13.4 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KER19408.1 - 0.00068 19.7 18.0 0.2 11.7 3.4 2.9 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KER19408.1 - 0.0096 16.1 13.0 0.099 12.8 2.3 2.4 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF885 PF05960.11 KER19408.1 - 0.011 15.4 3.2 0.013 15.2 3.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF3829 PF12889.7 KER19408.1 - 0.017 14.6 0.9 0.017 14.6 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) AI-2E_transport PF01594.16 KER19408.1 - 0.019 14.2 3.4 0.2 10.8 0.2 2.1 2 0 0 2 2 2 0 AI-2E family transporter SopA PF13981.6 KER19408.1 - 0.03 14.7 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 1 0 SopA-like central domain YojJ PF10372.9 KER19408.1 - 0.031 14.4 12.9 2.2 8.4 0.2 4.0 2 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus ERp29 PF07749.12 KER19408.1 - 0.035 15.0 6.5 0.31 12.0 3.9 2.8 1 1 1 2 2 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF1664 PF07889.12 KER19408.1 - 0.042 13.9 14.6 0.22 11.6 2.0 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Atypical_Card PF18461.1 KER19408.1 - 0.046 13.9 1.6 0.52 10.6 0.1 2.6 2 1 0 2 2 2 0 Atypical caspase recruitment domain ApoLp-III PF07464.11 KER19408.1 - 0.056 13.5 17.0 3.9 7.6 9.8 2.9 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4533 PF15047.6 KER19408.1 - 0.059 12.9 12.1 0.19 11.3 3.5 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF4533) LMBR1 PF04791.16 KER19408.1 - 0.06 12.3 8.7 0.068 12.1 8.1 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Phasin PF05597.11 KER19408.1 - 0.062 13.3 11.3 1.3 9.0 1.5 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Carbpep_Y_N PF05388.11 KER19408.1 - 0.069 13.7 7.3 0.72 10.4 1.5 2.6 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF1572 PF07609.11 KER19408.1 - 0.071 12.9 2.2 0.29 10.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1572) RhaA PF06134.11 KER19408.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Glyco_hydro_4C PF11975.8 KER19408.1 - 0.088 12.9 0.6 0.1 12.7 0.6 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Prefoldin_2 PF01920.20 KER19408.1 - 0.091 12.7 25.4 0.049 13.6 7.2 3.0 1 1 2 3 3 3 0 Prefoldin subunit RP-C_C PF11800.8 KER19408.1 - 0.093 12.8 3.1 0.1 12.7 1.0 2.1 1 1 1 2 2 1 0 Replication protein C C-terminal region Phlebovirus_NSM PF07246.11 KER19408.1 - 0.099 12.0 4.6 0.079 12.3 3.1 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M BAR PF03114.18 KER19408.1 - 0.12 12.0 10.8 3.5 7.2 8.9 2.2 1 1 1 2 2 2 0 BAR domain Lipoprotein_2 PF00921.17 KER19408.1 - 0.12 11.9 10.1 0.04 13.5 4.3 2.0 1 1 1 2 2 2 0 Borrelia lipoprotein Prominin PF05478.11 KER19408.1 - 0.12 10.3 13.0 0.18 9.7 6.4 1.8 1 1 1 2 2 2 0 Prominin DUF4407 PF14362.6 KER19408.1 - 0.12 11.7 8.8 0.38 10.1 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Erf4 PF10256.9 KER19408.1 - 0.17 12.0 1.2 0.79 9.8 0.4 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family T7SS_ESX_EspC PF10824.8 KER19408.1 - 0.18 12.3 0.9 4.4 7.8 0.0 2.8 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm RnlA_toxin PF15935.5 KER19408.1 - 0.18 11.5 8.1 0.73 9.6 3.1 2.4 1 1 1 2 2 2 0 RNase LS, bacterial toxin TipAS PF07739.13 KER19408.1 - 0.19 12.3 5.5 1.8 9.2 1.8 2.8 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Frankia_peptide PF14407.6 KER19408.1 - 0.22 11.5 2.3 1.1 9.2 0.4 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PLC-beta_C PF08703.10 KER19408.1 - 0.31 11.0 18.1 0.21 11.6 5.3 3.0 2 1 0 3 3 3 0 PLC-beta C terminal Allexi_40kDa PF05549.11 KER19408.1 - 0.35 10.3 13.6 0.74 9.3 1.8 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Exo5 PF09810.9 KER19408.1 - 0.37 10.2 5.2 0.5 9.8 5.2 1.2 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DUF2357 PF09823.9 KER19408.1 - 0.41 9.9 11.4 0.26 10.5 3.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2357) SICA_alpha PF12887.7 KER19408.1 - 0.41 10.5 13.9 0.74 9.7 6.9 2.7 1 1 0 2 2 2 0 SICA extracellular alpha domain Strumpellin PF10266.9 KER19408.1 - 0.44 8.2 9.3 0.17 9.5 7.1 1.4 1 1 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin YtxH PF12732.7 KER19408.1 - 0.44 11.1 12.2 3.3e+03 -1.3 12.2 3.3 1 1 0 1 1 0 0 YtxH-like protein YlqD PF11068.8 KER19408.1 - 0.45 10.9 14.1 0.049 14.0 2.5 3.0 1 1 2 3 3 3 0 YlqD protein DUF3958 PF13125.6 KER19408.1 - 0.5 10.6 12.7 0.61 10.3 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Peptidase_Prp PF04327.12 KER19408.1 - 0.51 10.6 8.1 3.6 7.9 1.5 2.5 2 1 0 2 2 2 0 Cysteine protease Prp Cas_DxTHG PF09455.10 KER19408.1 - 0.52 9.8 8.5 0.78 9.3 8.5 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Serine_rich PF08824.10 KER19408.1 - 0.53 10.3 8.4 0.4 10.7 1.3 2.6 1 1 2 3 3 3 0 Serine rich protein interaction domain Atg14 PF10186.9 KER19408.1 - 0.62 9.1 15.6 0.7 8.9 4.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CdvA PF18822.1 KER19408.1 - 0.66 9.8 22.7 5.3 6.9 1.7 4.1 3 2 1 4 4 4 0 CdvA-like coiled-coil domain PRESAN PF09687.10 KER19408.1 - 0.69 10.5 8.5 3.4 8.2 0.3 2.4 1 1 1 2 2 2 0 Plasmodium RESA N-terminal AbiH PF14253.6 KER19408.1 - 0.73 9.7 7.6 0.34 10.8 2.9 2.0 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH DUF948 PF06103.11 KER19408.1 - 0.76 10.1 13.3 1.4e+04 -3.6 13.3 3.7 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) FAP206 PF12018.8 KER19408.1 - 0.79 9.2 11.0 0.2 11.1 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function FAD-SLDH PF12318.8 KER19408.1 - 0.91 9.6 4.6 7.1 6.7 0.2 2.4 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4611 PF15387.6 KER19408.1 - 0.99 9.7 5.4 2.9 8.1 0.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF883 PF05957.13 KER19408.1 - 1 10.0 9.5 9.1 7.0 1.6 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Stathmin PF00836.19 KER19408.1 - 1.1 9.2 16.9 2.6 8.0 4.7 2.6 1 1 1 2 2 2 0 Stathmin family Exonuc_VII_L PF02601.15 KER19408.1 - 1.4 8.5 12.5 7.9 5.9 12.5 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit V-ATPase_G PF03179.15 KER19408.1 - 1.4 9.5 12.2 1.8 9.1 3.7 2.7 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Fzo_mitofusin PF04799.13 KER19408.1 - 1.4 8.5 14.4 0.62 9.6 5.3 2.9 1 1 2 3 3 3 0 fzo-like conserved region PIN_8 PF18476.1 KER19408.1 - 1.4 8.7 12.0 3.9 7.3 4.0 2.1 1 1 1 2 2 2 0 PIN like domain PEP-utilisers_N PF05524.13 KER19408.1 - 1.6 8.9 7.3 0.88 9.8 0.7 2.7 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal UPF0231 PF06062.11 KER19408.1 - 1.7 8.9 5.4 4.9 7.4 0.1 2.9 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Transposase_24 PF03004.14 KER19408.1 - 1.8 8.7 6.4 4.4 7.4 0.1 2.9 1 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) CCDC74_C PF14917.6 KER19408.1 - 1.8 9.1 5.9 0.37 11.3 1.6 2.1 2 1 0 2 2 1 0 Coiled coil protein 74, C terminal DUF2203 PF09969.9 KER19408.1 - 1.9 9.2 9.9 5.4 7.8 2.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Baculo_p24 PF05073.12 KER19408.1 - 2 8.2 11.1 2.1 8.1 1.8 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein FliH PF02108.16 KER19408.1 - 2 8.5 9.7 1.5 8.9 1.7 2.8 2 1 0 2 2 2 0 Flagellar assembly protein FliH GCIP PF13324.6 KER19408.1 - 2.1 7.9 9.7 1.9 8.0 0.4 2.1 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting MtrG PF04210.13 KER19408.1 - 2.4 8.1 5.4 20 5.1 0.4 3.6 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pex19 PF04614.12 KER19408.1 - 2.4 7.9 11.8 4 7.1 11.7 1.4 1 1 0 1 1 1 0 Pex19 protein family Nup54 PF13874.6 KER19408.1 - 2.6 8.1 12.5 6.9e+02 0.3 12.3 2.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SF-assemblin PF06705.11 KER19408.1 - 2.6 7.3 14.3 1.9 7.8 3.5 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin Peptidase_M3_N PF08439.10 KER19408.1 - 2.7 8.3 8.2 6 7.2 0.1 3.1 2 2 2 4 4 4 0 Oligopeptidase F DNA_photolyase PF00875.18 KER19408.1 - 3 7.8 4.6 8.9 6.3 0.2 2.8 1 1 1 4 4 4 0 DNA photolyase AAA_32 PF13654.6 KER19408.1 - 3.3 6.4 11.9 0.25 10.1 3.8 2.0 1 1 1 2 2 2 0 AAA domain MnmE_helical PF12631.7 KER19408.1 - 3.7 7.7 12.1 27 4.8 12.1 2.2 1 1 0 1 1 1 0 MnmE helical domain TMPIT PF07851.13 KER19408.1 - 4.3 6.5 13.3 5.7 6.1 2.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein DNA_primase_lrg PF04104.14 KER19408.1 - 5.2 6.4 10.5 1.3 8.4 2.9 2.4 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Wtap PF17098.5 KER19408.1 - 6 6.8 16.9 2 8.3 10.6 2.6 1 1 0 2 2 2 0 WTAP/Mum2p family CorA PF01544.18 KER19408.1 - 6.2 6.0 12.9 5 6.3 8.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein FapA PF03961.13 KER19408.1 - 6.3 5.3 18.1 4.1 5.9 4.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A HrpJ PF07201.11 KER19408.1 - 7.2 6.9 15.9 1.3 9.3 0.4 2.8 1 1 0 2 2 2 0 HrpJ-like domain Tweety PF04906.13 KER19408.1 - 7.4 5.1 11.1 13 4.3 0.5 2.6 1 1 2 3 3 3 0 Tweety IZUMO PF15005.6 KER19408.1 - 7.8 7.0 12.8 16 6.0 4.3 2.7 1 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4363 PF14276.6 KER19408.1 - 8.1 6.6 15.5 7.7 6.7 5.7 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4363) Prefoldin PF02996.17 KER19408.1 - 8.7 6.3 20.0 2.1 8.3 0.1 3.8 3 2 0 3 3 3 0 Prefoldin subunit EF-hand_6 PF13405.6 KER19409.1 - 2.9e-11 42.3 0.7 7.3e-05 22.4 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER19409.1 - 3.1e-11 42.0 4.2 0.00058 19.2 0.6 4.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KER19409.1 - 1e-09 38.7 0.5 0.00052 20.4 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair UPF0154 PF03672.13 KER19409.1 - 0.0009 19.2 0.0 0.74 9.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_8 PF13833.6 KER19409.1 - 0.0015 18.4 2.1 0.052 13.4 0.1 3.4 1 1 3 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 KER19409.1 - 0.0044 16.5 0.9 3.8 7.2 0.0 2.7 2 0 0 2 2 2 2 EF hand DUF5613 PF18467.1 KER19409.1 - 0.079 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) DDE_Tnp_IS66_C PF13817.6 KER19409.1 - 0.2 11.9 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element Gaa1 PF04114.14 KER19410.1 - 2.3e-100 337.0 7.5 8.1e-50 170.3 8.2 2.9 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component RVT_1 PF00078.27 KER19410.1 - 1.8e-28 99.6 0.0 4.5e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2275 PF10039.9 KER19413.1 - 0.025 14.7 0.2 0.054 13.6 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) YvrJ PF12841.7 KER19413.1 - 0.21 11.2 0.4 0.49 10.0 0.4 1.7 1 0 0 1 1 1 0 YvrJ protein family Erv26 PF04148.13 KER19415.1 - 1.1e-33 116.9 16.3 4.9e-33 114.7 16.3 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF4491 PF14898.6 KER19415.1 - 0.68 10.4 7.2 0.13 12.8 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Erv26 PF04148.13 KER19416.1 - 1.9e-33 116.1 15.7 8.5e-33 113.9 15.7 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF4491 PF14898.6 KER19416.1 - 0.59 10.6 6.8 0.13 12.8 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) COX5A PF02284.16 KER19417.1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Peptidase_C13 PF01650.18 KER19420.1 - 5.4e-100 334.1 5.3 7.2e-93 310.8 2.7 2.1 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER19420.1 - 0.0012 18.8 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Hap4_Hap_bind PF10297.9 KER19420.1 - 0.83 9.9 3.1 29 4.9 0.2 2.6 2 0 0 2 2 2 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Peptidase_C13 PF01650.18 KER19421.1 - 6.3e-17 61.9 0.0 7e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family DEAD PF00270.29 KER19422.1 - 1.4e-47 161.7 0.0 1.6e-46 158.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER19422.1 - 5.8e-26 91.0 1.6 2.3e-25 89.1 0.4 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KER19422.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 KER19422.1 - 0.094 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Parvo_NS1 PF01057.17 KER19426.1 - 4.9e-15 55.4 0.6 1.1e-14 54.2 0.3 1.7 1 1 1 2 2 2 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER19426.1 - 2.9e-12 46.2 0.1 3.7e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.6 KER19426.1 - 0.0047 17.0 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF4327 PF14217.6 KER19426.1 - 0.068 13.3 0.1 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) T2SSE PF00437.20 KER19426.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KER19426.1 - 0.11 12.0 0.1 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1778 PF08681.11 KER19426.1 - 0.15 12.0 0.1 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) OSCP PF00213.18 KER19427.1 - 1.6e-30 106.5 0.1 1.8e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PHD PF00628.29 KER19428.1 - 2.9e-25 87.9 39.7 6e-09 35.7 6.1 3.7 3 0 0 3 3 3 3 PHD-finger DDT PF02791.17 KER19428.1 - 6.1e-14 52.1 0.1 1.5e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 DDT domain RVT_1 PF00078.27 KER19428.1 - 6.9e-13 48.6 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bromodomain PF00439.25 KER19428.1 - 0.031 14.3 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Bromodomain KELK PF15796.5 KER19428.1 - 0.092 13.2 8.5 0.15 12.5 1.6 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GrpE PF01025.19 KER19428.1 - 0.44 10.2 8.4 0.67 9.6 3.2 2.6 2 0 0 2 2 2 0 GrpE zf-PHD-like PF15446.6 KER19428.1 - 2.5 7.7 18.9 2.2 7.8 4.4 3.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Spc24 PF08286.11 KER19428.1 - 2.8 8.2 8.0 30 4.9 0.2 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 KER19428.1 - 3.8 6.3 8.2 7.2 5.4 3.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-RING_2 PF13639.6 KER19428.1 - 6.3 7.2 40.8 7 7.1 6.0 3.8 3 0 0 3 3 3 0 Ring finger domain MT-A70 PF05063.14 KER19429.1 - 4.9e-60 202.4 0.0 1.1e-59 201.2 0.0 1.6 1 0 0 1 1 1 1 MT-A70 ThiD2 PF17792.1 KER19429.1 - 0.18 12.3 0.9 0.38 11.2 0.2 1.9 2 0 0 2 2 2 0 ThiD2 family PNP_UDP_1 PF01048.20 KER19431.1 - 3.6e-27 95.1 0.2 4.2e-27 94.9 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily RVT_1 PF00078.27 KER19432.1 - 5.1e-08 32.7 0.0 6.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_1 PF00018.28 KER19432.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 SH3 domain Peptidase_C13 PF01650.18 KER19434.1 - 1.4e-77 260.7 8.4 2.6e-75 253.3 8.4 3.1 1 1 0 1 1 1 1 Peptidase C13 family Pneumo_M2 PF07380.11 KER19436.1 - 1.4 9.2 4.8 28 5.1 0.0 3.2 3 1 1 4 4 4 0 Pneumovirus M2 protein Pkinase_Tyr PF07714.17 KER19444.1 - 1.2e-13 51.0 0.0 1.2e-06 28.1 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KER19444.1 - 2.7e-12 46.6 0.0 1.8e-05 24.3 0.0 3.6 4 0 0 4 4 4 2 Protein kinase domain Activin_recp PF01064.23 KER19444.1 - 0.0026 18.8 3.7 0.0029 18.7 0.6 2.5 2 0 0 2 2 2 1 Activin types I and II receptor domain CD34_antigen PF06365.12 KER19444.1 - 0.12 12.0 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family 2-oxoacid_dh PF00198.23 KER19445.1 - 1.5e-79 266.7 0.0 2.5e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KER19445.1 - 6.8e-17 61.1 2.0 1.3e-16 60.2 2.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KER19445.1 - 0.0017 18.2 0.3 0.0061 16.4 0.2 2.1 1 1 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 KER19445.1 - 0.015 15.2 0.4 0.068 13.1 0.1 2.1 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KER19445.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KER19445.1 - 0.058 13.3 0.4 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein MORN PF02493.20 KER19446.1 - 7e-33 110.6 46.8 4.5e-07 29.4 0.3 9.5 10 0 0 10 10 10 8 MORN repeat zf-RING_2 PF13639.6 KER19449.1 - 6.9e-10 39.1 8.7 6.9e-10 39.1 8.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KER19449.1 - 4.4e-08 32.7 5.0 1.4e-07 31.1 5.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KER19449.1 - 3e-06 27.1 4.6 6.8e-06 26.0 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KER19449.1 - 1.4e-05 24.9 8.7 1.4e-05 24.9 8.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER19449.1 - 1.6e-05 24.7 7.5 1.6e-05 24.7 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER19449.1 - 0.00018 21.7 8.1 0.00018 21.7 8.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KER19449.1 - 0.00035 20.5 5.0 0.00035 20.5 5.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER19449.1 - 0.0011 18.8 6.3 0.0011 18.8 6.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KER19449.1 - 0.0056 16.3 5.2 0.013 15.1 5.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KER19449.1 - 0.0088 16.1 4.5 0.022 14.8 4.5 1.7 1 1 0 1 1 1 1 Zinc-finger Prok-RING_1 PF14446.6 KER19449.1 - 0.35 10.8 6.7 0.41 10.6 3.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF746 PF05344.11 KER19452.1 - 0.096 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) FF PF01846.19 KER19456.1 - 3.5e-45 151.9 29.4 8.5e-14 51.5 1.5 4.7 4 0 0 4 4 4 4 FF domain WW PF00397.26 KER19456.1 - 5.2e-21 74.4 16.5 2.1e-08 34.1 3.9 3.9 3 0 0 3 3 3 3 WW domain TACC_C PF05010.14 KER19456.1 - 1.2e-08 34.9 14.5 1.2e-08 34.9 14.5 4.1 3 1 1 4 4 4 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RhoGAP-FF1 PF16512.5 KER19456.1 - 0.00018 22.1 1.9 0.00018 22.1 1.9 3.9 2 1 2 4 4 4 1 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KER19456.1 - 0.072 13.4 3.2 5.6 7.3 0.1 3.6 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Pox_F11 PF04943.12 KER19456.1 - 2.1 7.3 8.8 4 6.4 8.8 1.3 1 0 0 1 1 1 0 Poxvirus F11 protein COG5 PF10392.9 KER19460.1 - 0.029 14.5 0.3 0.061 13.5 0.3 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 HisKA PF00512.25 KER19460.1 - 0.13 12.4 0.4 0.21 11.6 0.4 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain RVT_1 PF00078.27 KER19461.1 - 2e-09 37.3 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fip1 PF05182.13 KER19463.1 - 2.8e-21 74.7 0.6 4.7e-21 74.0 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Sulfotransfer_3 PF13469.6 KER19464.1 - 7.6e-36 124.5 0.1 2.7e-35 122.7 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER19464.1 - 1.1e-10 41.5 0.2 7.5e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain V-set PF07686.17 KER19466.1 - 1.8e-08 34.5 0.2 2.8e-07 30.7 0.2 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.25 KER19466.1 - 3.4e-07 30.4 0.1 3.4e-05 23.9 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin domain I-set PF07679.16 KER19466.1 - 1.9e-06 27.8 0.0 1.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER19466.1 - 1.4e-05 25.6 0.0 0.00045 20.8 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER19466.1 - 0.0028 17.9 0.0 0.033 14.5 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER19466.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KER19467.1 - 2.8e-11 43.9 0.9 2e-06 28.3 0.0 3.9 2 2 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KER19467.1 - 1.7e-07 31.2 0.0 0.00021 21.3 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER19467.1 - 1.2e-05 25.6 0.5 4.5 7.7 0.1 4.1 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 KER19467.1 - 0.00057 20.0 0.0 4.8 7.4 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 KER19467.1 - 0.0021 18.2 4.1 0.53 10.5 0.1 3.8 4 1 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.12 KER19467.1 - 0.0058 16.7 1.0 2.6 8.2 0.1 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Goodbye PF17109.5 KER19468.1 - 0.11 12.9 0.9 0.25 11.8 0.8 1.6 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Peptidase_C13 PF01650.18 KER19469.1 - 4.2e-67 226.4 5.9 9.6e-39 133.4 0.2 2.2 1 1 1 2 2 2 2 Peptidase C13 family Bud13 PF09736.9 KER19471.1 - 3.5e-42 144.2 9.5 5.4e-42 143.6 9.5 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex SYF2 PF08231.12 KER19471.1 - 0.14 12.5 13.5 0.26 11.7 13.5 1.4 1 0 0 1 1 1 0 SYF2 splicing factor GCS PF03074.16 KER19471.1 - 0.79 9.0 4.1 0.66 9.3 2.3 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase DUF1043 PF06295.12 KER19471.1 - 2.2 8.3 7.6 5 7.2 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Y_phosphatase PF00102.27 KER19474.1 - 5.9e-46 156.9 0.1 9.1e-43 146.5 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KER19474.1 - 1.9e-12 47.3 4.4 0.75 10.2 0.0 7.3 8 0 0 8 8 8 5 Fibronectin type III domain DSPc PF00782.20 KER19474.1 - 0.0076 16.1 1.0 0.025 14.4 1.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Glyco_hydro_36C PF16874.5 KER19474.1 - 0.0095 16.4 0.0 5.1 7.7 0.0 3.7 5 0 0 5 5 5 1 Glycosyl hydrolase family 36 C-terminal domain Y_phosphatase3 PF13350.6 KER19474.1 - 0.12 12.3 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family RPN7 PF10602.9 KER19475.1 - 1.7e-40 138.5 0.0 3.8e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KER19475.1 - 1.1e-13 51.5 0.0 3.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 KER19475.1 - 0.011 15.9 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER19475.1 - 0.036 14.2 0.2 0.16 12.1 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER19475.1 - 0.08 12.8 0.2 0.23 11.4 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Dynein_light PF01221.18 KER19476.1 - 9.8e-23 80.3 0.1 1.1e-22 80.2 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 KER19476.1 - 0.068 13.2 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 RNR_N PF08343.10 KER19476.1 - 0.09 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Ribonuc_L-PSP PF01042.21 KER19477.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease L-PSP V-ATPase_H_C PF11698.8 KER19478.1 - 0.07 13.2 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Asp PF00026.23 KER19479.1 - 2.8e-20 73.0 0.0 3.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER19479.1 - 3.2e-07 30.7 0.1 2.6e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal P16-Arc PF04699.14 KER19485.1 - 1.7e-42 145.4 0.1 1.9e-42 145.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KER19485.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.6 1 1 1 2 2 2 0 Dip2/Utp12 Family DnaB_2 PF07261.11 KER19485.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment Peptidase_C13 PF01650.18 KER19486.1 - 5.6e-29 101.4 0.7 2.4e-19 69.8 0.1 2.2 1 1 1 2 2 2 2 Peptidase C13 family Pkinase PF00069.25 KER19487.1 - 7.2e-43 146.8 0.2 2.5e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER19487.1 - 5.4e-21 75.0 2.0 1.2e-09 37.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KER19487.1 - 3.4e-05 23.6 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 NB-ARC PF00931.22 KER19487.1 - 0.039 13.1 0.1 8.6 5.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2987 PF11205.8 KER19487.1 - 0.063 13.2 0.1 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) DUF4555 PF15093.6 KER19487.1 - 0.13 11.6 0.1 15 4.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4555) Pkinase PF00069.25 KER19488.1 - 1.6e-14 53.9 0.2 4.4e-12 45.9 0.0 2.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_C PF00433.24 KER19488.1 - 1.4e-10 41.7 4.2 9e-10 39.1 1.5 3.3 3 0 0 3 3 3 1 Protein kinase C terminal domain zf-C3HC4_3 PF13920.6 KER19488.1 - 8.8e-08 31.9 8.3 2.1e-07 30.7 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER19488.1 - 5.3e-06 26.2 11.7 1.5e-05 24.8 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER19488.1 - 2.7e-05 23.9 5.8 6.8e-05 22.7 5.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KER19488.1 - 7.1e-05 22.6 10.3 0.00018 21.3 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER19488.1 - 9.5e-05 22.3 11.1 9.5e-05 22.3 11.1 2.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KER19488.1 - 0.00085 19.6 6.1 0.003 17.8 6.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER19488.1 - 0.0012 18.8 7.0 0.0035 17.3 7.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KER19488.1 - 0.0028 17.9 9.4 0.0079 16.5 9.4 1.8 1 0 0 1 1 1 1 Ring finger domain Pkinase_Tyr PF07714.17 KER19488.1 - 0.0054 16.0 0.0 0.0054 16.0 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase ATG16 PF08614.11 KER19488.1 - 0.0056 16.9 9.1 0.0056 16.9 9.1 8.0 3 2 4 7 7 5 3 Autophagy protein 16 (ATG16) zf-ANAPC11 PF12861.7 KER19488.1 - 0.011 15.8 1.4 0.027 14.5 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3947 PF13135.6 KER19488.1 - 0.12 12.6 5.1 0.47 10.7 5.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) zf-C3HC4_4 PF15227.6 KER19488.1 - 0.17 12.1 7.5 0.48 10.6 7.5 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KER19488.1 - 0.29 11.0 1.3 0.76 9.7 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 KER19488.1 - 1.7 8.6 7.4 6.4 6.7 7.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_15 PF17032.5 KER19488.1 - 6.8 7.5 10.4 2.6 8.9 6.2 2.3 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 KER19488.1 - 9.7 6.3 13.3 30 4.7 8.6 2.6 2 0 0 2 2 2 0 Double zinc ribbon RVT_1 PF00078.27 KER19490.1 - 8.6e-09 35.2 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KER19493.1 - 1.9e-12 47.2 0.0 5.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3110 PF11360.8 KER19493.1 - 0.032 14.4 0.2 9.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) EF-hand_14 PF17959.1 KER19493.1 - 0.092 13.1 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain ParB_C PF18064.1 KER19493.1 - 0.096 12.9 1.2 2.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Centromere-binding protein ParB C-terminal DsrD PF08679.11 KER19493.1 - 0.11 12.8 0.1 31 4.9 0.0 2.8 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) EF-hand_7 PF13499.6 KER19494.1 - 1.1e-17 64.2 3.6 4.4e-10 39.9 1.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER19494.1 - 1e-14 53.1 5.9 4.3e-05 23.1 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KER19494.1 - 6.2e-14 50.4 8.5 0.00078 18.8 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 KER19494.1 - 3.1e-12 45.4 4.8 0.00015 21.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KER19494.1 - 3.6e-06 26.7 3.9 0.093 12.6 0.0 3.6 2 1 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER19494.1 - 6.4e-06 26.5 0.6 0.005 17.2 0.3 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.11 KER19494.1 - 0.018 15.5 0.5 0.056 13.9 0.1 1.9 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Dockerin_1 PF00404.18 KER19494.1 - 0.059 13.6 1.5 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Dockerin type I domain Mito_carr PF00153.27 KER19495.1 - 2.7e-20 72.1 0.6 1.7e-12 47.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 KER19496.1 - 5.5e-51 170.5 3.0 4.8e-23 80.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4586 PF15239.6 KER19498.1 - 9.9e-81 272.2 0.4 1.1e-80 272.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) CH PF00307.31 KER19501.1 - 4.8e-24 84.7 0.5 4.2e-15 55.8 0.0 4.8 4 1 1 5 5 5 3 Calponin homology (CH) domain DUF948 PF06103.11 KER19501.1 - 0.011 15.9 4.5 19 5.6 0.0 6.3 7 0 0 7 7 7 0 Bacterial protein of unknown function (DUF948) CAMSAP_CH PF11971.8 KER19501.1 - 0.013 15.3 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 CAMSAP CH domain NPV_P10 PF05531.12 KER19501.1 - 0.21 12.1 12.9 12 6.4 0.0 7.4 8 0 0 8 8 8 0 Nucleopolyhedrovirus P10 protein COMMD1_N PF17221.3 KER19501.1 - 0.26 11.6 3.0 34 4.8 0.1 3.6 3 0 0 3 3 3 0 COMMD1 N-terminal domain DUF16 PF01519.16 KER19501.1 - 1.2 9.7 17.3 10 6.7 0.0 6.4 7 0 0 7 7 7 0 Protein of unknown function DUF16 SAM_KSR1 PF13543.6 KER19501.1 - 1.4 9.0 6.3 40 4.3 0.0 4.5 3 1 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 PHM7_cyt PF14703.6 KER19501.1 - 5 7.3 10.7 0.45 10.7 0.3 3.9 4 1 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Rpn9_C PF18261.1 KER19502.1 - 6.1e-05 22.5 2.0 0.00016 21.2 1.1 2.2 2 0 0 2 2 2 1 Rpn9 C-terminal helix DUF3658 PF12395.8 KER19502.1 - 0.076 12.9 8.8 0.29 11.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function DASH_Dad1 PF08649.10 KER19502.1 - 0.69 10.1 15.7 0.96 9.7 0.5 7.4 6 0 0 6 6 6 0 DASH complex subunit Dad1 I-set PF07679.16 KER19503.1 - 4.6e-09 36.2 0.0 1.6e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER19503.1 - 8.7e-08 32.7 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER19503.1 - 5.1e-05 23.5 0.0 0.00082 19.7 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER19503.1 - 0.15 12.3 0.1 0.42 10.8 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain RFX_DNA_binding PF02257.15 KER19505.1 - 4.5e-28 97.7 0.3 7.9e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain RFX5_N PF18326.1 KER19505.1 - 0.066 13.0 0.0 0.27 11.0 0.0 2.1 1 0 0 1 1 1 0 RFX5 N-terminal domain Pox_D5 PF03288.16 KER19505.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like WD40 PF00400.32 KER19506.1 - 4.1e-38 128.7 21.7 2.6e-09 37.5 0.1 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KER19506.1 - 7.4e-10 38.1 0.6 0.0046 15.7 0.0 4.6 3 1 1 4 4 4 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KER19506.1 - 1.2e-09 38.3 1.1 0.11 12.7 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER19506.1 - 7.5e-08 31.5 2.5 0.022 13.4 0.1 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KER19506.1 - 3.2e-05 24.2 0.9 2 9.0 0.1 4.7 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 KER19506.1 - 7.9e-05 22.4 0.0 0.044 13.3 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.6 KER19506.1 - 0.0023 18.0 0.2 0.36 10.9 0.0 3.8 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 KER19506.1 - 0.041 13.3 0.1 0.15 11.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) PQQ PF01011.21 KER19506.1 - 0.09 12.7 0.2 0.89 9.6 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Mito_carr PF00153.27 KER19507.1 - 1.9e-52 175.1 0.6 4.5e-19 68.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CUB PF00431.20 KER19509.1 - 2.2e-18 66.6 0.0 1.6e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 CUB domain polyprenyl_synt PF00348.17 KER19509.1 - 0.2 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase CUB PF00431.20 KER19510.1 - 2e-21 76.4 0.0 2.3e-12 47.2 0.0 2.0 2 0 0 2 2 2 2 CUB domain CDC45 PF02724.14 KER19512.1 - 0.0033 15.8 2.8 0.0031 15.9 2.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KER19512.1 - 0.47 8.6 12.2 0.55 8.4 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KER19512.1 - 0.52 9.6 7.3 0.59 9.4 7.3 1.1 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 KER19512.1 - 0.55 8.8 4.3 0.58 8.7 4.3 1.2 1 0 0 1 1 1 0 Utp14 protein LuxT_C PF18285.1 KER19513.1 - 0.15 12.7 0.1 0.57 10.8 0.0 1.8 1 1 1 2 2 2 0 Tetracycline repressor LuxT C-terminal domain RRM_5 PF13893.6 KER19515.1 - 1e-36 125.3 2.0 4.8e-29 100.5 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER19515.1 - 2.4e-28 97.8 0.2 4.8e-07 29.5 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER19515.1 - 4.2e-06 26.5 0.5 0.98 9.3 0.0 4.5 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_7 PF16367.5 KER19515.1 - 0.011 15.9 0.0 8.5 6.6 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif PNISR PF15996.5 KER19515.1 - 0.53 10.5 2.9 0.69 10.2 0.6 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Prefoldin_2 PF01920.20 KER19516.1 - 6.9e-15 54.9 0.1 8.5e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF5339 PF17274.2 KER19516.1 - 0.056 14.3 3.9 2.3 9.2 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Stork_head PF10264.9 KER19517.1 - 2.1e-25 88.7 0.1 4.2e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Mob1_phocein PF03637.17 KER19519.1 - 1.4e-26 93.5 0.7 5.1e-26 91.7 0.7 1.8 1 1 0 1 1 1 1 Mob1/phocein family zf-CCCH PF00642.24 KER19520.1 - 9.5e-13 47.7 26.2 3.2e-06 26.9 0.3 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER19520.1 - 2.3e-12 46.5 44.9 1.2e-06 28.4 2.0 6.8 6 1 0 6 6 6 3 Zinc finger domain zf-CCCH_4 PF18044.1 KER19520.1 - 1.1e-08 34.7 4.3 2.5e-05 24.0 0.4 4.9 5 0 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KER19520.1 - 4.2e-08 33.8 27.8 0.0002 22.0 0.3 5.7 1 1 5 6 6 6 3 Torus domain zf-CCCH_3 PF15663.5 KER19520.1 - 8.2e-08 32.4 19.7 8.9e-08 32.3 6.5 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCHC PF00098.23 KER19520.1 - 4.9e-05 23.2 3.5 4.9e-05 23.2 3.5 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_2 PF14608.6 KER19520.1 - 5.2e-05 23.6 37.9 0.00093 19.6 1.2 5.9 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC_4 PF14392.6 KER19520.1 - 0.22 11.3 8.0 2.4 7.9 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 KER19520.1 - 1.3 8.8 14.0 1.7 8.4 0.1 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain DUF1677 PF07911.13 KER19520.1 - 1.8 9.0 6.6 6.9 7.1 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) zf-C2H2_10 PF16588.5 KER19520.1 - 3.8 7.3 11.7 0.41 10.4 2.0 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 KER19520.1 - 4.6 7.3 8.9 0.27 11.2 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle Solute_trans_a PF03619.16 KER19521.1 - 1.3e-61 208.5 16.9 9e-35 120.5 3.7 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha DHHC PF01529.20 KER19521.1 - 4 7.6 13.4 0.41 10.7 0.3 2.9 2 1 1 3 3 3 0 DHHC palmitoyltransferase Ank_4 PF13637.6 KER19522.1 - 0.0001 22.8 0.0 0.25 12.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER19522.1 - 0.0014 19.1 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER19522.1 - 0.003 17.8 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) HSP90 PF00183.18 KER19524.1 - 2.2e-197 657.1 9.5 2.2e-197 657.1 9.5 1.8 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 KER19524.1 - 7.4e-10 39.3 1.4 1.7e-09 38.2 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KER19524.1 - 8.3e-10 38.6 0.2 2.7e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prefoldin_2 PF01920.20 KER19525.1 - 2.3e-12 46.8 0.3 3.2e-12 46.3 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Malectin PF11721.8 KER19526.1 - 7.9e-33 113.9 0.0 9.4e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Malectin domain Antimicrobial_1 PF08018.11 KER19526.1 - 1.2 9.4 5.5 2 8.7 5.5 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide Ribosomal_L29 PF00831.23 KER19528.1 - 3e-15 55.9 2.8 3.4e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF4376 PF14301.6 KER19528.1 - 0.0079 16.5 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4376) V_ATPase_I PF01496.19 KER19528.1 - 0.02 12.8 0.1 0.026 12.5 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRIP PF01465.20 KER19528.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 GRIP domain FlxA PF14282.6 KER19528.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 FlxA-like protein TolA_bind_tri PF16331.5 KER19528.1 - 0.083 13.0 1.2 0.84 9.8 0.0 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Hexapep PF00132.24 KER19529.1 - 2.7e-12 45.9 14.5 2.9e-06 26.8 2.6 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KER19529.1 - 5.6e-08 32.4 4.5 0.0069 16.1 0.2 3.6 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KER19529.1 - 0.016 14.1 2.5 0.068 12.1 0.2 2.0 1 1 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 KER19529.1 - 0.073 11.2 1.3 0.11 10.6 0.7 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) PTPA PF03095.15 KER19530.1 - 6.7e-109 364.0 0.0 7.8e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CAP_N PF01213.19 KER19530.1 - 0.48 9.8 2.2 0.84 9.1 2.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-rbx1 PF12678.7 KER19531.1 - 0.00019 21.7 4.2 0.00049 20.3 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KER19531.1 - 0.004 17.2 8.8 0.0051 16.8 8.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Myc_N PF01056.18 KER19532.1 - 0.059 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Calreticulin PF00262.18 KER19533.1 - 1.9e-81 273.8 15.9 9.9e-60 202.3 7.6 2.3 1 1 1 2 2 2 2 Calreticulin family SHR3_chaperone PF08229.11 KER19533.1 - 5.4 5.9 5.0 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 ER membrane protein SH3 Topoisom_I_N PF02919.15 KER19535.1 - 4.2e-99 330.3 1.6 4.2e-99 330.3 1.6 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KER19535.1 - 1.5e-97 325.4 4.4 1.5e-97 325.4 4.4 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KER19535.1 - 2.1e-33 114.1 1.3 7.2e-33 112.3 1.3 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Syntaxin_2 PF14523.6 KER19535.1 - 0.0049 17.2 7.2 0.0049 17.2 7.2 2.8 2 0 0 2 2 2 1 Syntaxin-like protein RBP_receptor PF14752.6 KER19538.1 - 2.3e-48 165.2 31.2 1.7e-47 162.4 31.2 1.9 1 1 0 1 1 1 1 Retinol binding protein receptor RVT_1 PF00078.27 KER19540.1 - 5.4e-07 29.4 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4840 PF16128.5 KER19540.1 - 0.069 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) E1_DerP2_DerF2 PF02221.15 KER19541.1 - 4.1e-09 37.0 0.1 4.7e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 ML domain Vfa1 PF08432.10 KER19542.1 - 0.0094 16.3 0.0 0.011 16.1 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MBOAT PF03062.19 KER19543.1 - 5.4e-27 95.1 8.5 5.4e-27 95.1 8.5 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family TMIE PF16038.5 KER19543.1 - 0.044 13.6 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 TMIE protein DUF1925 PF09094.11 KER19543.1 - 0.071 13.4 0.8 0.37 11.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Methyltransf_28 PF02636.17 KER19544.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tetraspanin PF00335.20 KER19545.1 - 3.4e-13 49.8 0.1 4.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Oxidored_q2 PF00420.24 KER19545.1 - 1.9 8.1 6.7 4.1 7.1 6.7 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Syja_N PF02383.18 KER19546.1 - 1.2e-63 215.4 0.0 4.1e-63 213.6 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain 7tm_1 PF00001.21 KER19548.1 - 6.8e-09 35.4 15.7 9e-09 35.0 15.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER19548.1 - 0.11 11.9 10.1 0.41 10.0 10.1 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Cullin PF00888.22 KER19553.1 - 5.1e-147 491.1 12.0 7.2e-147 490.6 12.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KER19553.1 - 2.2e-20 72.5 3.2 9.1e-20 70.5 1.2 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain IFT81_CH PF18383.1 KER19553.1 - 0.32 11.3 7.4 0.19 12.0 2.1 3.0 3 0 0 3 3 3 0 Intraflagellar transport 81 calponin homology domain Pur_ac_phosph_N PF16656.5 KER19554.1 - 0.00043 20.8 0.7 0.00043 20.8 0.7 1.6 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KER19554.1 - 0.0063 16.8 0.4 0.012 15.9 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III domain fn3 PF00041.21 KER19555.1 - 6.4e-14 52.1 10.4 0.0011 19.3 0.1 4.4 4 0 0 4 4 4 4 Fibronectin type III domain HSL_N PF06350.12 KER19555.1 - 5.2e-07 28.9 0.2 0.025 13.6 0.0 2.3 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus Pur_ac_phosph_N PF16656.5 KER19555.1 - 4.5e-05 23.9 9.9 1.6 9.4 0.8 4.3 3 1 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KER19555.1 - 8.9 6.7 8.5 2.4 8.5 0.1 3.4 3 1 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.21 KER19557.1 - 6.3e-07 29.6 2.6 0.0065 16.8 0.0 3.2 3 1 0 3 3 3 2 Fibronectin type III domain SH3_10 PF17902.1 KER19558.1 - 0.0038 17.3 0.3 1.1 9.4 0.0 3.0 2 0 0 2 2 2 2 SH3 domain Rop-like PF05082.13 KER19558.1 - 0.051 13.4 0.0 0.26 11.1 0.0 2.2 1 0 0 1 1 1 0 Rop-like RVT_1 PF00078.27 KER19559.1 - 0.0064 16.0 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5548 PF17702.1 KER19559.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5548) Exo_endo_phos PF03372.23 KER19561.1 - 2.2e-11 43.7 0.1 3.1e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER19561.1 - 0.00014 21.7 1.1 0.42 10.5 0.2 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase DUF5532 PF17673.1 KER19561.1 - 0.01 15.9 0.2 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Cas_APE2256 PF09651.10 KER19561.1 - 0.14 12.1 0.8 25 4.8 0.0 2.9 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_APE2256) SH3_10 PF17902.1 KER19562.1 - 2.2e-07 30.8 0.0 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 SH3 domain DM4_12 PF07841.13 KER19562.1 - 0.042 14.5 0.3 0.17 12.6 0.1 2.1 2 0 0 2 2 2 0 DM4/DM12 family SH3_1 PF00018.28 KER19563.1 - 7.1e-28 96.0 0.6 2.8e-11 42.8 0.0 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 KER19563.1 - 5e-22 77.3 0.2 4.2e-06 26.3 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 KER19563.1 - 1.3e-17 63.3 1.5 3.5e-07 30.0 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain Thymopoietin PF08198.11 KER19563.1 - 0.097 12.3 0.3 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Thymopoietin protein DUF3850 PF12961.7 KER19563.1 - 0.11 12.5 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) Dynamin_M PF01031.20 KER19564.1 - 4.2e-100 334.6 1.4 4.2e-100 334.6 1.4 1.6 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KER19564.1 - 1e-23 83.3 1.8 2.4e-23 82.1 1.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_N PF00350.23 KER19564.1 - 2.5e-13 50.4 0.0 8.4e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Dynamin family PH PF00169.29 KER19564.1 - 3e-09 37.3 0.3 6.1e-09 36.3 0.3 1.5 1 0 0 1 1 1 1 PH domain DASH_Duo1 PF08651.10 KER19564.1 - 0.065 13.0 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 QIL1 PF15884.5 KER19564.1 - 0.092 13.3 0.1 0.47 11.1 0.0 2.2 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 EF-hand_1 PF00036.32 KER19567.1 - 1.7e-18 64.7 7.6 5.2e-05 22.5 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KER19567.1 - 1.3e-17 64.0 12.5 1.3e-07 31.9 3.6 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KER19567.1 - 3.6e-14 51.4 6.6 0.015 15.2 0.0 5.4 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KER19567.1 - 1.5e-12 47.2 3.4 0.0019 18.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KER19567.1 - 1.2e-07 30.9 14.6 0.021 14.3 0.1 4.7 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 KER19567.1 - 8.8e-06 26.0 6.5 0.00075 19.8 1.9 2.9 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region YrzK PF17449.2 KER19567.1 - 1.5 9.2 4.3 10 6.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized YrzK-like EF-hand_1 PF00036.32 KER19568.1 - 7.9e-13 47.0 0.2 0.0068 15.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER19568.1 - 6.3e-11 42.6 4.4 0.00024 21.5 0.6 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KER19568.1 - 8.9e-11 40.8 0.2 0.017 15.0 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KER19568.1 - 4.4e-10 38.6 0.6 0.0055 16.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KER19568.1 - 9.5e-08 31.8 0.9 0.056 13.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KER19568.1 - 0.0032 17.4 1.2 0.014 15.4 0.0 2.4 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER19568.1 - 0.0045 17.3 2.5 0.81 10.0 0.1 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Asp PF00026.23 KER19569.1 - 7.1e-32 111.1 0.0 9.9e-22 77.7 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER19569.1 - 3.2e-10 40.5 0.0 3.9e-05 24.0 0.1 2.7 1 1 2 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER19569.1 - 0.008 16.8 0.0 5.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KER19569.1 - 0.022 15.3 0.0 5.9 7.5 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF155 PF02582.14 KER19569.1 - 0.18 11.9 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Peptidase_C13 PF01650.18 KER19575.1 - 9.3e-66 221.9 0.5 1.3e-65 221.5 0.5 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19575.1 - 5.6e-05 23.2 0.0 6.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Mo25 PF08569.11 KER19577.1 - 5e-121 404.1 7.5 5.9e-121 403.8 7.5 1.0 1 0 0 1 1 1 1 Mo25-like Kinesin PF00225.23 KER19579.1 - 2.8e-83 279.6 0.2 9.5e-83 277.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KER19579.1 - 2.7e-46 157.2 0.9 1.9e-45 154.5 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding APC_N_CC PF16689.5 KER19579.1 - 0.39 10.8 15.2 12 6.0 0.2 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain YabA PF06156.13 KER19579.1 - 6.3 7.5 30.1 1.3 9.7 3.0 5.4 3 1 2 5 5 5 0 Initiation control protein YabA Pentapeptide_4 PF13599.6 KER19580.1 - 1.4e-37 127.7 0.0 0.00028 21.0 0.0 13.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Lamprin PF06403.11 KER19580.1 - 7.8e-14 51.8 3.9 2.9 7.8 0.1 8.9 1 1 2 3 3 3 3 Lamprin Cation_ATPase_C PF00689.21 KER19581.1 - 1.4e-43 148.7 5.9 1.9e-43 148.3 5.9 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KER19581.1 - 4.2e-16 59.9 0.0 8.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KER19581.1 - 1.4e-06 28.3 2.6 2.9e-06 27.2 0.8 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KER19581.1 - 1.9e-06 28.4 0.0 1.3e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RepB-RCR_reg PF10723.9 KER19581.1 - 0.2 11.6 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB E1-E2_ATPase PF00122.20 KER19583.1 - 9.5e-50 168.6 3.3 1.1e-48 165.1 0.3 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KER19583.1 - 3.9e-17 61.7 0.1 3.9e-17 61.7 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KER19583.1 - 4.1e-13 49.2 0.0 8.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KER19583.1 - 0.049 13.9 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FYDLN_acid PF09538.10 KER19584.1 - 4.5 8.0 25.6 5.4 7.7 25.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Trypan_PARP PF05887.11 KER19584.1 - 6.1 6.8 20.7 6.6 6.7 20.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TetR_C_27 PF17935.1 KER19587.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MH2 PF03166.14 KER19592.1 - 1.3e-75 253.8 0.4 2.1e-75 253.0 0.4 1.4 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KER19592.1 - 2.8e-40 136.7 0.4 5.9e-40 135.7 0.4 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KER19592.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 P-mevalo_kinase PF04275.14 KER19598.1 - 7.2e-28 96.8 0.0 1.1e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomevalonate kinase BAG PF02179.16 KER19599.1 - 3.5e-11 43.4 0.3 4e-11 43.2 0.3 1.1 1 0 0 1 1 1 1 BAG domain Peptidase_C13 PF01650.18 KER19601.1 - 1e-99 333.2 2.8 1.6e-99 332.6 2.8 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19601.1 - 0.0026 17.8 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Asp PF00026.23 KER19603.1 - 1.1e-12 48.1 0.0 1.8e-12 47.4 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER19603.1 - 7.3e-05 22.6 0.0 9.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Beach PF02138.18 KER19604.1 - 2.4e-104 348.6 0.0 4.1e-104 347.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KER19604.1 - 1.6e-08 34.5 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Transglut_core3 PF13471.6 KER19604.1 - 0.031 14.2 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily Galactosyl_T PF01762.21 KER19606.1 - 3.9e-41 141.0 0.0 5.7e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KER19606.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Hyccin PF09790.9 KER19607.1 - 2e-19 69.9 3.1 2.2e-14 53.3 1.8 3.2 2 1 0 2 2 2 2 Hyccin ubiquitin PF00240.23 KER19608.1 - 2.6e-07 30.3 0.1 7.3e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KER19608.1 - 6.9e-05 23.2 0.0 0.0004 20.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KER19608.1 - 0.018 14.8 0.1 0.079 12.8 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DEAD PF00270.29 KER19611.1 - 7.3e-42 143.1 0.5 1.1e-41 142.5 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER19611.1 - 3.3e-28 98.2 0.9 1.2e-27 96.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KER19611.1 - 0.0026 17.0 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KER19611.1 - 0.0057 16.0 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SwrA PF17423.2 KER19611.1 - 0.087 12.8 0.6 0.21 11.6 0.6 1.7 1 0 0 1 1 1 0 Swarming motility protein RT_RNaseH_2 PF17919.1 KER19612.1 - 6e-22 77.6 0.0 9.4e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER19612.1 - 5.7e-20 71.6 0.0 8.2e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_C13 PF01650.18 KER19615.1 - 6.9e-50 169.9 1.7 3.6e-42 144.7 0.1 2.8 3 0 0 3 3 3 2 Peptidase C13 family ABC_tran PF00005.27 KER19616.1 - 3.4e-52 176.6 0.0 6.1e-25 88.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KER19616.1 - 2.3e-19 70.3 0.2 0.00021 21.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER19616.1 - 4e-09 37.3 1.9 0.0018 18.9 0.4 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 KER19616.1 - 3.4e-08 33.0 40.0 7e-06 25.4 5.5 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KER19616.1 - 3.2e-07 30.4 0.1 0.0046 16.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KER19616.1 - 7e-07 28.9 1.2 0.027 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KER19616.1 - 7.5e-05 22.5 0.1 0.41 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KER19616.1 - 9.9e-05 22.8 0.0 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KER19616.1 - 0.00013 21.5 0.0 1 8.8 0.1 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KER19616.1 - 0.00086 19.1 0.1 0.5 10.1 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_15 PF13175.6 KER19616.1 - 0.0039 17.0 0.0 0.093 12.4 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 KER19616.1 - 0.0068 16.0 0.4 3.7 7.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KER19616.1 - 0.0068 16.7 0.2 0.89 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KER19616.1 - 0.011 15.6 0.2 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KER19616.1 - 0.015 15.5 0.0 3.1 8.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain GTP_EFTU PF00009.27 KER19616.1 - 0.022 14.3 0.1 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER19616.1 - 0.033 14.3 0.4 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KER19616.1 - 0.12 12.0 0.4 10 5.7 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KER19616.1 - 0.12 12.0 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KER19616.1 - 0.13 12.8 0.1 7.3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KER19616.1 - 0.16 10.6 0.2 1.1 7.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KER19616.1 - 0.18 11.7 0.3 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NPP1 PF05630.11 KER19616.1 - 0.2 11.8 0.6 0.37 10.9 0.6 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) AAA_28 PF13521.6 KER19616.1 - 0.24 11.6 1.4 4.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KER19616.1 - 0.39 10.3 1.1 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Wzy_C PF04932.15 KER19616.1 - 2.2 7.9 7.8 10 5.7 0.3 3.3 3 0 0 3 3 3 0 O-Antigen ligase Aldedh PF00171.22 KER19618.1 - 2.5e-161 537.3 0.0 2.7e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mito_carr PF00153.27 KER19619.1 - 6.2e-33 112.6 0.6 1.1e-18 66.9 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein ROQ_II PF18386.1 KER19619.1 - 0.031 14.1 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Roquin II domain CUB PF00431.20 KER19621.1 - 2.6e-18 66.3 0.0 1e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 CUB domain DUF2207 PF09972.9 KER19621.1 - 0.06 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) tRNA-synt_1d PF00750.19 KER19622.1 - 1e-17 64.1 0.0 3.3e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KER19622.1 - 4.1e-15 56.0 0.0 1.1e-13 51.4 0.0 2.3 1 1 0 1 1 1 1 DALR anticodon binding domain dUTPase PF00692.19 KER19625.1 - 1e-29 102.8 0.0 1.4e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase 60KD_IMP PF02096.20 KER19626.1 - 1.1e-28 100.2 6.5 1.5e-28 99.8 6.5 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Kinesin PF00225.23 KER19628.1 - 3.4e-74 249.7 4.9 2.7e-70 236.9 0.1 2.7 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KER19628.1 - 2.9e-44 150.6 0.2 9.1e-44 149.0 0.0 2.0 3 0 0 3 3 3 1 Microtubule binding DUF4795 PF16043.5 KER19628.1 - 0.012 15.2 0.8 0.021 14.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) YabA PF06156.13 KER19628.1 - 0.68 10.6 6.6 2.5 8.8 2.3 2.9 2 1 1 3 3 3 0 Initiation control protein YabA SMC_N PF02463.19 KER19636.1 - 1.8e-77 259.7 0.8 2.6e-77 259.2 0.8 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KER19636.1 - 1.3e-19 70.7 0.0 1.8e-11 44.4 0.0 2.8 2 0 0 2 2 2 2 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KER19636.1 - 8.5e-15 55.3 0.0 1.6e-11 44.6 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KER19636.1 - 1.4e-13 51.8 0.0 1.4e-13 51.8 0.0 6.0 3 2 2 5 5 3 1 AAA domain AAA_21 PF13304.6 KER19636.1 - 6.9e-10 39.2 11.4 5.3e-05 23.2 0.0 3.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KER19636.1 - 7.2e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KER19636.1 - 0.00016 20.5 29.8 0.00016 20.5 29.8 4.0 2 2 2 4 4 3 1 AAA domain Laminin_II PF06009.12 KER19636.1 - 0.00046 20.2 8.2 0.00046 20.2 8.2 7.2 3 2 3 7 7 7 2 Laminin Domain II ATG16 PF08614.11 KER19636.1 - 0.00061 20.1 11.3 0.00061 20.1 11.3 6.7 2 2 4 6 6 6 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KER19636.1 - 0.00092 19.3 23.0 0.00092 19.3 23.0 7.2 2 2 5 7 7 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 KER19636.1 - 0.0015 17.9 24.3 0.0015 17.9 24.3 6.6 3 2 3 7 7 6 1 Tropomyosin EzrA PF06160.12 KER19636.1 - 0.0019 16.4 17.2 0.0019 16.4 17.2 5.1 2 2 3 5 5 5 1 Septation ring formation regulator, EzrA MscS_porin PF12795.7 KER19636.1 - 0.0027 17.3 18.8 0.0027 17.3 18.8 6.4 2 2 4 6 6 3 2 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 KER19636.1 - 0.005 16.2 16.4 0.005 16.2 16.4 7.0 2 2 4 7 7 7 1 Protein of unknown function (DUF3450) DUF2935 PF11155.8 KER19636.1 - 0.14 12.5 3.8 2.5 8.4 0.2 4.3 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) Flagellin_C PF00700.21 KER19636.1 - 0.41 11.0 3.6 2 8.8 0.8 3.7 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region Spc7 PF08317.11 KER19636.1 - 0.74 8.6 109.2 1 8.2 13.6 6.6 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.27 KER19636.1 - 0.95 10.0 0.0 0.95 10.0 0.0 5.1 3 2 0 4 4 3 0 ABC transporter Fib_alpha PF08702.10 KER19636.1 - 2.6 8.2 53.8 0.024 14.9 2.5 6.8 3 2 3 7 7 7 0 Fibrinogen alpha/beta chain family TFIID-18kDa PF02269.16 KER19639.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit 4HBT_3 PF13622.6 KER19640.1 - 2.5e-36 126.2 0.0 8.9e-36 124.4 0.0 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily MULE PF10551.9 KER19640.1 - 6.3e-20 71.4 0.8 1.6e-19 70.1 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain Acyl_CoA_thio PF02551.15 KER19640.1 - 3.3e-13 49.6 0.0 3.1e-08 33.5 0.0 3.4 3 0 0 3 3 3 2 Acyl-CoA thioesterase FAR1 PF03101.15 KER19640.1 - 0.0035 18.0 1.8 0.012 16.3 1.8 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain Spectrin PF00435.21 KER19645.1 - 1.7e-48 163.4 39.0 3.1e-10 40.5 0.1 8.8 8 1 1 9 9 9 8 Spectrin repeat PH_9 PF15410.6 KER19645.1 - 3.2e-17 63.0 0.0 1.2e-16 61.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER19645.1 - 4e-12 46.6 0.0 2.7e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 PH domain DUF5082 PF16888.5 KER19645.1 - 0.00068 19.9 23.2 0.56 10.5 1.8 5.4 5 0 0 5 5 5 3 Domain of unknown function (DUF5082) DUF713 PF05218.14 KER19645.1 - 0.018 14.8 5.0 1.8 8.2 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF713) FHIPEP PF00771.20 KER19645.1 - 0.1 11.0 1.5 0.21 10.0 1.5 1.4 1 0 0 1 1 1 0 FHIPEP family CLZ PF16526.5 KER19645.1 - 0.19 12.1 15.7 5.5 7.4 0.1 5.5 5 1 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PilJ PF13675.6 KER19645.1 - 0.3 11.1 18.4 0.13 12.3 0.4 5.1 5 0 0 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term GD_AH_C PF04295.13 KER19646.1 - 0.0038 16.1 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 2 D-galactarate dehydratase / Altronate hydrolase, C terminus ECD PF18432.1 KER19646.1 - 0.098 12.6 0.0 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Extracellular Cadherin domain GCV_T PF01571.21 KER19647.1 - 2.8e-76 256.3 0.0 3.6e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KER19647.1 - 4.8e-20 71.3 0.0 2e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain DUF1899 PF08953.11 KER19648.1 - 2.7e-31 107.2 0.0 5e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KER19648.1 - 2.1e-20 72.3 0.2 4.1e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KER19648.1 - 1.5e-07 32.0 3.6 0.007 17.2 0.3 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER19648.1 - 1.8e-05 24.9 0.1 0.16 12.3 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain P_C PF06640.11 KER19648.1 - 0.019 15.1 0.4 0.034 14.3 0.4 1.3 1 0 0 1 1 1 0 P protein C-terminus NUDIX PF00293.28 KER19651.1 - 5.3e-07 29.7 0.1 7.5e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain L51_S25_CI-B8 PF05047.16 KER19652.1 - 7e-09 35.5 0.1 1.6e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sec63 PF02889.16 KER19654.1 - 6.3e-158 523.7 0.1 2e-85 286.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KER19654.1 - 4.8e-44 150.2 0.0 7.9e-23 81.1 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KER19654.1 - 1.1e-34 118.9 0.1 2.8e-34 117.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KER19654.1 - 3.6e-21 75.9 0.0 1.2e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KER19654.1 - 8.6e-08 32.5 0.0 3.6e-06 27.3 0.0 3.5 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KER19654.1 - 4.2e-05 23.8 0.0 0.13 12.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KER19654.1 - 0.0025 16.9 0.0 0.25 10.4 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KER19654.1 - 0.006 16.3 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein PhoH PF02562.16 KER19654.1 - 0.0079 15.7 0.0 0.66 9.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 KER19654.1 - 0.0083 15.7 0.0 1.9 7.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KER19654.1 - 0.011 15.5 0.4 8.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KER19654.1 - 0.015 14.9 0.0 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KER19654.1 - 0.04 13.7 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KER19654.1 - 0.12 12.1 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain FAM184 PF15665.5 KER19655.1 - 6.8e-05 22.8 5.5 9.5e-05 22.3 5.5 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF5001 PF16392.5 KER19656.1 - 0.057 13.3 2.0 0.1 12.5 0.3 2.3 2 0 0 2 2 2 0 Ig-like domain Dickkopf_N PF04706.12 KER19657.1 - 0.4 11.2 16.0 0.5 10.9 3.3 2.5 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KER19657.1 - 3.9 7.9 17.1 7 7.0 17.1 1.6 1 1 0 1 1 1 0 EB module ZT_dimer PF16916.5 KER19658.1 - 5.1e-10 39.3 0.7 7.7e-10 38.8 0.7 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 KER19658.1 - 1.5e-06 28.1 0.2 2.1e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Cation efflux family SET PF00856.28 KER19659.1 - 8.1e-09 36.1 0.0 8.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KER19659.1 - 0.0001 22.2 0.3 1.1 9.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.18 KER19659.1 - 0.00081 19.4 9.6 0.00081 19.4 9.6 2.8 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.28 KER19659.1 - 0.0075 16.0 0.1 2.2 8.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER19659.1 - 0.12 12.6 0.7 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 KER19661.1 - 4.8e-10 40.1 0.0 7.2e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 KER19661.1 - 0.00032 20.4 1.1 2.9 7.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-MYND PF01753.18 KER19661.1 - 0.00065 19.7 8.9 0.00065 19.7 8.9 3.3 2 1 0 2 2 2 1 MYND finger TPR_2 PF07719.17 KER19661.1 - 0.0019 18.2 3.4 1.2 9.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat RecO_C PF02565.15 KER19661.1 - 0.014 15.2 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Recombination protein O C terminal TPR_12 PF13424.6 KER19661.1 - 0.74 10.2 6.5 5.9 7.3 2.1 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat CHASE3 PF05227.13 KER19661.1 - 3 7.8 5.1 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 CHASE3 domain TraB PF01963.17 KER19663.1 - 6.4e-14 52.5 0.0 1.1e-12 48.4 0.0 2.1 1 1 0 1 1 1 1 TraB family TraB PF01963.17 KER19664.1 - 1.4e-30 107.1 0.0 1.6e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 TraB family TcpQ PF10671.9 KER19665.1 - 0.076 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q 7tm_1 PF00001.21 KER19666.1 - 2.3e-09 37.0 5.5 2.3e-09 37.0 5.5 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF434 PF04256.12 KER19669.1 - 0.087 12.5 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF434) DUF2070 PF09843.9 KER19674.1 - 0.0092 14.3 10.3 0.011 14.0 10.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF2583 PF10762.9 KER19674.1 - 0.068 13.6 1.6 0.087 13.2 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) L_HMGIC_fpl PF10242.9 KER19674.1 - 0.66 10.1 11.3 2.9 8.1 3.8 2.4 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein DUF5518 PF17647.1 KER19674.1 - 1.6 8.9 10.3 0.38 10.9 5.6 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5518) SUR7 PF06687.12 KER19674.1 - 3.2 7.3 15.2 0.22 11.2 9.3 1.7 1 1 1 2 2 2 0 SUR7/PalI family Far-17a_AIG1 PF04750.14 KER19680.1 - 5.5e-18 65.0 19.6 1.1e-17 64.1 19.6 1.4 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein CYSTM PF12734.7 KER19680.1 - 0.007 16.7 0.3 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Mob1_phocein PF03637.17 KER19682.1 - 1.6e-75 252.8 0.2 2.1e-75 252.4 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family MH2 PF03166.14 KER19682.1 - 6.9e-24 85.1 0.0 1.1e-23 84.5 0.0 1.3 1 0 0 1 1 1 1 MH2 domain THDPS_N_2 PF14805.6 KER19682.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Sec63 PF02889.16 KER19683.1 - 6.3e-10 38.6 1.0 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain Amidase_2 PF01510.25 KER19684.1 - 2.2e-11 44.3 0.0 6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Phage_holin_2_1 PF04971.12 KER19684.1 - 0.046 13.7 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S Phage_holin_2_3 PF16080.5 KER19684.1 - 0.11 12.2 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin family HP1 LRR_8 PF13855.6 KER19685.1 - 1.9e-22 78.8 15.5 5e-09 35.8 5.3 4.7 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KER19685.1 - 1.1e-13 51.1 14.4 4.3e-05 23.8 2.7 4.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KER19685.1 - 5.5e-06 26.4 0.0 0.001 19.0 0.0 2.8 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KER19685.1 - 3.8e-05 23.6 18.5 2.3 9.1 0.1 7.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KER19685.1 - 0.027 14.0 0.5 9.9 5.6 0.1 2.8 1 1 1 2 2 2 0 Leucine-rich repeat Homeodomain PF00046.29 KER19686.1 - 4.7e-22 77.6 4.1 1.1e-21 76.4 4.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER19686.1 - 0.019 14.8 1.0 0.033 14.1 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain DEAD PF00270.29 KER19688.1 - 4.3e-39 134.1 0.1 9.2e-39 133.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER19688.1 - 2.1e-24 86.0 0.1 4.5e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER19688.1 - 4.2e-05 23.6 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER19688.1 - 0.79 10.0 3.1 0.61 10.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain Cystatin PF00031.21 KER19689.1 - 0.002 18.4 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 KER19689.1 - 0.016 15.5 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Glyco_hydro_35 PF01301.19 KER19691.1 - 6.3e-208 689.7 0.0 1.2e-103 347.1 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KER19691.1 - 3e-24 86.1 3.7 2.1e-10 40.5 0.2 4.1 2 2 0 2 2 2 2 Beta-galactosidase AP_endonuc_2 PF01261.24 KER19691.1 - 0.081 12.4 0.0 35 3.8 0.0 3.7 4 0 0 4 4 4 0 Xylose isomerase-like TIM barrel TTL PF03133.15 KER19692.1 - 2.9e-72 243.3 0.0 6.6e-54 183.0 0.0 2.6 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER19692.1 - 4.9e-07 29.3 1.0 8.7e-05 21.9 0.0 3.4 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER19692.1 - 5.3e-06 25.9 0.0 0.036 13.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KER19692.1 - 0.019 15.0 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain PQ-loop PF04193.14 KER19693.1 - 1.9e-19 69.2 1.1 6.2e-19 67.5 1.1 1.9 1 0 0 1 1 1 1 PQ loop repeat Collagen PF01391.18 KER19694.1 - 0.00012 21.7 16.9 0.00012 21.7 16.9 5.3 5 0 0 5 5 5 2 Collagen triple helix repeat (20 copies) ChiC PF06483.11 KER19694.1 - 0.091 12.7 0.1 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Chitinase C HSCB_C PF07743.13 KER19694.1 - 0.25 11.9 0.9 0.54 10.8 0.9 1.5 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain RVT_1 PF00078.27 KER19695.1 - 2.9e-06 27.0 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Diphthamide_syn PF01866.17 KER19697.1 - 3.1e-60 204.2 0.0 4.5e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Sugar_tr PF00083.24 KER19698.1 - 9.6e-26 90.6 15.3 4.3e-25 88.5 15.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER19698.1 - 1.4e-20 73.6 29.9 2.7e-18 66.0 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 KER19699.1 - 3.5e-35 121.5 47.5 4.8e-35 121.1 47.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_L18 PF17135.4 KER19701.1 - 6.2e-89 296.4 1.9 6.8e-89 296.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KER19701.1 - 0.017 15.8 0.1 0.062 14.0 0.1 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A STAC2_u1 PF16664.5 KER19706.1 - 0.037 14.5 0.0 4.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF5074 PF16819.5 KER19706.1 - 0.044 13.8 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) DND1_DSRM PF14709.7 KER19706.1 - 0.044 14.1 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PilJ_C PF18223.1 KER19706.1 - 0.11 13.0 0.0 25 5.4 0.0 2.2 2 0 0 2 2 2 0 Pili PilJ C-terminal domain Transposase_1 PF01359.18 KER19706.1 - 0.58 10.0 3.5 18 5.3 0.3 2.4 2 0 0 2 2 2 0 Transposase (partial DDE domain) WD40 PF00400.32 KER19707.1 - 5.2e-09 36.6 5.9 0.2 12.6 0.4 6.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER19707.1 - 0.011 16.0 0.0 0.94 9.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CDH-cyt PF16010.5 KER19707.1 - 0.46 10.1 3.9 1.6 8.4 3.9 1.9 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Zn_ribbon_17 PF17120.5 KER19707.1 - 4.9 6.8 11.3 0.039 13.6 2.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Iso_dh PF00180.20 KER19708.1 - 2.8e-70 237.2 0.1 1.1e-67 228.6 0.0 2.1 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase ZT_dimer PF16916.5 KER19708.1 - 0.028 14.6 2.6 12 6.1 0.1 3.6 3 1 0 3 3 3 0 Dimerisation domain of Zinc Transporter FtsA PF14450.6 KER19708.1 - 0.1 13.0 0.8 17 5.9 0.1 2.7 1 1 1 2 2 2 0 Cell division protein FtsA IQ PF00612.27 KER19709.1 - 3.6e-60 194.1 183.1 1.5e-05 24.3 1.1 22.0 21 1 1 22 22 22 17 IQ calmodulin-binding motif CH PF00307.31 KER19709.1 - 4e-05 23.8 0.0 0.032 14.4 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER19709.1 - 0.0042 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain ASH PF15780.5 KER19709.1 - 0.0077 16.4 0.0 0.92 9.8 0.0 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Asp PF00026.23 KER19711.1 - 7e-25 88.1 0.1 2.5e-22 79.7 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER19711.1 - 5e-06 26.9 0.2 3.2e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal FabA PF07977.13 KER19711.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 FabA-like domain TRAM_LAG1_CLN8 PF03798.16 KER19712.1 - 4.2e-22 78.9 21.3 5.4e-22 78.5 21.3 1.2 1 0 0 1 1 1 1 TLC domain CoatB PF10389.9 KER19712.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage coat protein B PEN-2 PF10251.9 KER19712.1 - 0.28 11.6 8.9 1.2 9.6 1.3 2.8 2 1 1 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Menin PF05053.13 KER19714.1 - 2e-92 310.7 1.6 1.8e-43 148.9 0.0 7.1 6 1 0 7 7 7 6 Menin TPR_2 PF07719.17 KER19714.1 - 1.2 9.4 3.8 0.86 9.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER19714.1 - 5.5 7.4 5.3 4 7.8 0.6 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.6 KER19715.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KER19717.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_1 PF00018.28 KER19720.1 - 1.7e-07 30.8 0.4 7.4e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Rrp15p PF07890.12 KER19720.1 - 0.26 11.6 5.3 0.57 10.5 5.3 1.5 1 0 0 1 1 1 0 Rrp15p Med9 PF07544.13 KER19720.1 - 0.3 11.2 3.4 0.55 10.4 0.4 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cupin_4 PF08007.12 KER19720.1 - 1.7 8.0 6.8 0.31 10.5 2.5 1.9 2 1 1 3 3 3 0 Cupin superfamily protein DUF948 PF06103.11 KER19720.1 - 2.1 8.7 3.2 16 5.9 0.2 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Muted PF14942.6 KER19720.1 - 6.5 7.1 12.9 0.7 10.2 0.2 3.2 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein bZIP_2 PF07716.15 KER19720.1 - 8 6.6 8.6 27 4.9 0.2 3.9 3 1 1 4 4 4 0 Basic region leucine zipper Mob1_phocein PF03637.17 KER19721.1 - 3.3e-76 255.0 0.2 3.8e-76 254.8 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Nop14 PF04147.12 KER19722.1 - 2.6e-26 92.2 29.8 1e-17 63.7 10.5 3.6 2 2 0 2 2 2 2 Nop14-like family NRIP1_repr_3 PF15689.5 KER19722.1 - 0.011 16.0 0.1 0.037 14.3 0.1 1.9 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 P-mevalo_kinase PF04275.14 KER19722.1 - 0.028 14.3 0.2 0.095 12.7 0.2 1.9 1 0 0 1 1 1 0 Phosphomevalonate kinase Pkinase PF00069.25 KER19723.1 - 4.5e-56 190.1 0.0 5.7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19723.1 - 2.8e-23 82.5 0.0 4.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER19723.1 - 0.00069 19.6 0.2 0.0044 17.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KER19723.1 - 0.0024 17.3 0.2 0.0038 16.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KER19723.1 - 0.026 14.1 0.1 0.052 13.1 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KER19723.1 - 0.047 13.3 1.5 0.11 12.1 0.8 1.9 2 1 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 KER19723.1 - 0.1 11.9 0.2 6 6.1 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Pox_MCEL PF03291.16 KER19724.1 - 1.4e-63 215.0 0.0 1.9e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KER19724.1 - 9.5e-14 51.9 0.0 2.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER19724.1 - 6.8e-11 42.2 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER19724.1 - 9.1e-09 35.9 0.0 2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER19724.1 - 1.5e-06 28.8 0.0 5.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER19724.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KER19724.1 - 0.0059 15.8 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 KER19724.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RIBIOP_C PF04950.12 KER19726.1 - 2.5e-84 283.1 0.1 4.1e-65 220.1 0.1 2.6 3 0 0 3 3 3 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KER19726.1 - 0.049 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 AARP2CN (NUC121) domain MOZART2 PF12926.7 KER19727.1 - 0.14 11.8 0.3 0.36 10.5 0.1 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Pkinase PF00069.25 KER19728.1 - 2.5e-62 210.7 0.0 5.1e-62 209.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19728.1 - 8.9e-24 84.2 0.0 2.3e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER19728.1 - 3.9e-05 22.8 1.0 0.0018 17.3 1.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER19728.1 - 0.00014 21.3 0.2 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KER19728.1 - 0.0015 17.9 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KER19728.1 - 0.033 13.3 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KER19728.1 - 0.056 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 KER19729.1 - 3.1e-13 50.0 9.7 0.027 15.4 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KER19729.1 - 0.0069 15.1 1.9 4.4 5.8 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Marek_SORF3 PF07153.11 KER19729.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein zf-met PF12874.7 KER19731.1 - 0.00042 20.6 0.8 0.00042 20.6 0.8 4.4 7 0 0 7 7 7 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KER19731.1 - 0.00067 19.4 0.1 0.00067 19.4 0.1 3.6 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KER19731.1 - 0.0017 18.7 0.4 0.0017 18.7 0.4 4.4 5 0 0 5 5 5 1 Zinc finger, C2H2 type Vps36-NZF-N PF16988.5 KER19731.1 - 0.0063 15.9 2.7 0.94 8.9 0.0 3.5 3 0 0 3 3 3 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF4329 PF14220.6 KER19731.1 - 0.14 12.2 0.2 0.42 10.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) DZR PF12773.7 KER19731.1 - 8.4 6.5 14.2 0.63 10.1 1.3 3.8 3 0 0 3 3 3 0 Double zinc ribbon Homeodomain PF00046.29 KER19732.1 - 1.2e-29 101.9 3.2 3.7e-15 55.5 0.1 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 KER19732.1 - 6.5e-06 26.0 0.5 0.061 13.2 0.0 3.1 3 0 0 3 3 3 2 Homeobox KN domain Homez PF11569.8 KER19732.1 - 0.0037 16.7 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF4709 PF15821.5 KER19732.1 - 0.051 13.9 1.2 0.13 12.5 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Peptidase_C13 PF01650.18 KER19733.1 - 4.9e-63 213.0 0.4 6.7e-63 212.6 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19733.1 - 0.0012 18.8 0.3 0.0019 18.2 0.0 1.6 2 0 0 2 2 2 1 Caspase domain E1_DerP2_DerF2 PF02221.15 KER19734.1 - 1.5e-05 25.4 0.0 1.6e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 ML domain Asp PF00026.23 KER19735.1 - 1.1e-41 143.3 0.0 1.6e-41 142.8 0.0 1.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER19735.1 - 2.5e-05 24.1 0.0 7.8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KER19735.1 - 0.1 12.8 0.0 3.2 8.0 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Peptidase_C13 PF01650.18 KER19737.1 - 7.4e-49 166.6 0.1 1.6e-48 165.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase C13 family PLAC8 PF04749.17 KER19739.1 - 1.5e-14 54.8 20.3 2e-14 54.4 20.3 1.2 1 0 0 1 1 1 1 PLAC8 family zf-C2H2 PF00096.26 KER19741.1 - 1.2e-20 72.7 29.4 3.3e-06 27.3 0.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER19741.1 - 9.2e-13 47.9 35.2 9.6e-05 22.9 0.4 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER19741.1 - 4.1e-12 45.9 27.2 7.6e-06 26.1 0.2 4.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER19741.1 - 1e-10 41.6 12.9 0.0089 16.3 0.7 4.6 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER19741.1 - 8.2e-08 32.4 19.6 0.0021 18.4 0.5 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER19741.1 - 9.1e-05 22.4 22.8 0.0055 16.7 0.3 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 KER19741.1 - 0.0017 18.6 2.2 0.0017 18.6 2.2 3.1 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KER19741.1 - 0.017 15.5 21.5 3.6 8.1 6.4 4.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 KER19741.1 - 0.18 12.0 11.5 0.29 11.3 2.1 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KER19741.1 - 0.3 11.9 9.2 0.74 10.6 1.3 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-C2HC_2 PF13913.6 KER19741.1 - 0.41 10.6 15.5 14 5.7 0.1 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-BED PF02892.15 KER19741.1 - 1.6 8.8 21.5 8 6.6 0.1 4.8 3 1 1 4 4 3 0 BED zinc finger zf-C2H2_2 PF12756.7 KER19741.1 - 1.8 9.0 18.5 0.53 10.6 0.4 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Ras PF00071.22 KER19743.1 - 2.2e-54 183.4 0.0 2.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER19743.1 - 2.1e-23 82.8 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER19743.1 - 7.1e-09 35.4 0.0 8.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family UPF0086 PF01868.16 KER19747.1 - 7.5e-17 61.0 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Ig_3 PF13927.6 KER19748.1 - 4.6e-08 33.5 0.2 6.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KER19748.1 - 0.00018 21.5 0.1 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain CcmD PF04995.14 KER19748.1 - 0.0012 18.9 0.1 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Ig_2 PF13895.6 KER19748.1 - 0.06 13.7 0.3 1.8 9.0 0.1 2.8 2 1 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 KER19748.1 - 0.071 13.3 0.3 0.37 11.0 0.0 2.2 2 1 0 2 2 2 0 Immunoglobulin domain FCH PF00611.23 KER19751.1 - 2.7e-06 27.5 0.7 7.5e-06 26.1 0.3 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 KER19752.1 - 6.4e-14 51.4 0.0 1.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KER19752.1 - 9.6e-11 41.4 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER19752.1 - 2.1e-10 40.1 0.1 3.8e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain HR1 PF02185.16 KER19752.1 - 0.0049 17.0 0.5 0.013 15.6 0.1 2.0 2 0 0 2 2 2 1 Hr1 repeat COX5A PF02284.16 KER19754.1 - 1.7e-35 121.1 0.0 2e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Laminin_EGF PF00053.24 KER19755.1 - 2.6e-114 373.3 248.9 3.9e-12 46.1 15.5 13.6 12 1 1 13 13 13 13 Laminin EGF domain Laminin_N PF00055.17 KER19755.1 - 7.4e-28 97.7 0.1 7.4e-28 97.7 0.1 3.5 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) GidB PF02527.15 KER19755.1 - 0.042 13.2 0.6 0.11 11.9 0.6 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF150 PF02576.17 KER19755.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RimP N-terminal domain HetR_C PF18460.1 KER19755.1 - 0.17 11.9 0.2 0.76 9.7 0.2 2.2 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Spidroin_N PF16763.5 KER19755.1 - 0.37 10.8 2.6 0.7 9.9 0.3 2.3 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Cbl_N PF02262.16 KER19755.1 - 0.96 9.5 3.8 67 3.5 0.4 3.6 2 1 1 3 3 3 0 CBL proto-oncogene N-terminal domain 1 DUF713 PF05218.14 KER19755.1 - 4 7.1 13.6 0.8 9.4 1.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF713) PXA PF02194.15 KER19756.1 - 7.4e-45 153.1 2.0 2.2e-44 151.6 2.0 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KER19756.1 - 1e-20 74.4 0.0 4.3e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KER19756.1 - 2.5e-16 59.7 0.1 6.7e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 PX domain Pfg27 PF09216.10 KER19756.1 - 0.041 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Pfg27 POB3_N PF17292.2 KER19757.1 - 3.5e-25 88.3 0.1 3.3e-22 78.7 0.1 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 KER19757.1 - 8.6e-23 80.6 0.0 2.1e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SSrecog PF03531.14 KER19757.1 - 1.9e-18 66.1 0.1 1.9e-18 66.1 0.1 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 KER19757.1 - 5.9e-15 55.4 0.6 1.4e-14 54.3 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER19757.1 - 3.2e-11 43.7 0.7 3.2e-11 43.7 0.7 2.0 2 0 0 2 2 2 1 HMG-box domain CDC45 PF02724.14 KER19757.1 - 0.62 8.3 13.1 0.92 7.7 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KER19757.1 - 7.4 4.6 8.5 12 3.8 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SH3BP5 PF05276.14 KER19759.1 - 2.6e-66 223.7 16.9 3.8e-66 223.2 16.9 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) FliJ PF02050.16 KER19759.1 - 0.0039 17.4 6.8 0.0039 17.4 6.8 2.8 2 1 0 2 2 2 1 Flagellar FliJ protein UvsY PF11056.8 KER19759.1 - 0.038 14.4 2.9 0.094 13.1 0.8 2.1 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DUF3232 PF11554.8 KER19759.1 - 0.058 13.8 2.8 11 6.5 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3232) YkyA PF10368.9 KER19759.1 - 0.35 10.5 8.9 0.065 12.9 3.2 2.5 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein SLATT_1 PF18181.1 KER19759.1 - 0.74 9.8 3.3 4.1 7.3 0.3 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DHR10 PF18595.1 KER19759.1 - 3.6 7.7 16.3 2.2 8.3 6.0 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain T3SSipB PF16535.5 KER19759.1 - 8 6.9 9.2 9.1 6.7 0.7 2.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB Exonuc_VII_L PF02601.15 KER19759.1 - 9.2 5.7 17.6 30 4.0 6.2 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit TMPIT PF07851.13 KER19759.1 - 9.9 5.3 11.5 1.3 8.2 1.0 2.2 2 0 0 2 2 2 0 TMPIT-like protein Acyl-CoA_dh_N PF02771.16 KER19761.1 - 2.6e-17 63.5 0.0 6.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KER19761.1 - 3.8e-13 49.9 0.1 9.2e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF498 PF04430.14 KER19761.1 - 2.8e-09 37.0 0.1 6.2e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Acyl-CoA_dh_M PF02770.19 KER19761.1 - 2.4e-07 30.8 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AA_permease_2 PF13520.6 KER19763.1 - 2.5e-44 151.8 29.2 2.5e-44 151.8 29.2 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KER19763.1 - 1.1e-28 100.1 27.8 1.1e-28 100.1 27.8 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KER19763.1 - 2.4e-19 69.2 9.2 2.4e-19 69.2 9.2 4.9 6 0 0 6 6 6 1 C-terminus of AA_permease NtA PF03146.15 KER19764.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Agrin NtA domain TPMT PF05724.11 KER19765.1 - 1.2e-23 83.9 0.0 1.4e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) EF-hand_13 PF17958.1 KER19765.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain ARTD15_N PF18084.1 KER19765.1 - 0.24 11.7 1.2 6.1 7.2 0.1 2.6 3 0 0 3 3 3 0 ARTD15 N-terminal domain Pecanex_C PF05041.15 KER19766.1 - 5.8e-98 327.0 0.0 9e-98 326.4 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) TCTP PF00838.17 KER19770.1 - 0.1 13.0 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein 7tm_1 PF00001.21 KER19771.1 - 1.6e-05 24.3 20.1 0.0017 17.8 16.5 3.0 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER19771.1 - 0.00016 21.1 29.0 0.0031 16.9 20.9 3.6 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KER19771.1 - 0.00028 20.6 7.0 0.00028 20.6 7.0 3.4 4 0 0 4 4 4 2 Serpentine type 7TM GPCR chemoreceptor Srx ERAP1_C PF11838.8 KER19773.1 - 2.5e-29 102.8 0.2 9.4e-28 97.7 0.1 2.0 1 1 1 2 2 2 1 ERAP1-like C-terminal domain DUF1206 PF06724.11 KER19773.1 - 0.00063 19.8 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1206) NIBRIN_BRCT_II PF16508.5 KER19773.1 - 0.027 14.8 0.2 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein HAMP_N3 PF18575.1 KER19773.1 - 0.073 12.7 0.0 19 4.9 0.0 2.6 3 0 0 3 3 3 0 HAMP N-terminal domain 3 KRAB PF01352.27 KER19773.1 - 2.6 7.8 3.9 40 4.0 0.0 3.1 3 0 0 3 3 3 0 KRAB box E1-E2_ATPase PF00122.20 KER19776.1 - 8.1e-05 22.2 0.4 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Alpha_E2_glycop PF00943.19 KER19777.1 - 0.074 11.8 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein UCH PF00443.29 KER19779.1 - 0.0092 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RL10P_insert PF17777.1 KER19780.1 - 6e-23 80.6 0.0 1.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KER19780.1 - 1.8e-11 44.0 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Transglut_core PF01841.19 KER19780.1 - 0.0028 18.1 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily COQ9 PF08511.11 KER19781.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 COQ9 gag-asp_proteas PF13975.6 KER19781.1 - 0.00039 20.9 0.0 0.0014 19.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER19781.1 - 0.00047 20.8 0.0 0.0014 19.2 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease Cep57_CLD PF14073.6 KER19781.1 - 0.041 13.9 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 RVP PF00077.20 KER19781.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DNA_primase_lrg PF04104.14 KER19783.1 - 8.1e-76 254.9 0.0 2.9e-75 253.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit RVT_1 PF00078.27 KER19783.1 - 7e-30 104.2 0.0 2e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KER19783.1 - 1.5e-21 76.6 0.1 3.3e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER19783.1 - 5.4e-20 71.3 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Guanylate_cyc PF00211.20 KER19785.1 - 1.6e-32 112.6 0.0 1.6e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain BCMA-Tall_bind PF09257.10 KER19787.1 - 0.14 12.3 2.6 12 6.0 0.1 2.6 3 0 0 3 3 3 0 BCMA, TALL-1 binding UPF0444 PF15475.6 KER19788.1 - 0.082 13.2 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 GAS PF13851.6 KER19788.1 - 4.5 6.6 83.5 0.44 9.9 22.6 4.7 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Pkinase PF00069.25 KER19790.1 - 5.1e-41 140.8 1.3 7.3e-41 140.3 1.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19790.1 - 6.3e-25 87.9 0.7 9.3e-25 87.4 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER19790.1 - 0.00013 21.0 0.2 0.0002 20.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER19790.1 - 0.041 13.2 0.3 0.074 12.4 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KER19791.1 - 8.4e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Otopetrin PF03189.13 KER19792.1 - 2.9e-117 392.2 17.5 3.6e-117 391.9 17.5 1.1 1 0 0 1 1 1 1 Otopetrin Mpp10 PF04006.12 KER19795.1 - 1.1e-30 106.8 6.1 1.2e-30 106.6 6.1 1.0 1 0 0 1 1 1 1 Mpp10 protein DUF4061 PF13270.6 KER19795.1 - 0.16 12.3 1.9 0.16 12.3 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) LicD PF04991.13 KER19796.1 - 0.047 13.8 0.1 0.51 10.4 0.0 2.1 1 1 0 2 2 2 0 LicD family DUF2428 PF10350.9 KER19797.1 - 7.8e-45 153.3 0.4 2.3e-44 151.7 0.4 1.8 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) MBD_C PF14048.6 KER19798.1 - 9.1e-29 100.0 0.2 1.8e-28 99.1 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.19 KER19798.1 - 1.9e-12 46.7 0.1 4.2e-12 45.6 0.1 1.7 1 1 0 1 1 1 1 Methyl-CpG binding domain MBDa PF16564.5 KER19798.1 - 2.2e-05 24.5 0.2 8.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 p55-binding region of Methyl-CpG-binding domain proteins MBD COesterase PF00135.28 KER19799.1 - 5.8e-127 424.7 0.0 9.5e-87 292.0 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KER19799.1 - 0.00012 22.1 2.2 0.00066 19.6 2.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 KER19800.1 - 2.3e-14 53.0 26.7 1.3e-05 25.3 2.0 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KER19800.1 - 1.3e-07 31.3 23.3 9.5e-05 22.1 1.0 4.0 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KER19800.1 - 1.4e-07 31.8 32.8 0.0012 19.5 1.8 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER19800.1 - 3.2e-05 24.2 5.9 0.0048 17.3 0.6 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER19800.1 - 0.011 16.0 5.2 2.1 8.7 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KER19800.1 - 0.016 14.9 7.6 0.016 14.9 7.6 5.1 5 1 0 5 5 4 0 C2H2-type zinc-finger domain A2L_zn_ribbon PF08792.10 KER19800.1 - 0.035 13.8 0.4 0.035 13.8 0.4 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF2321 PF10083.9 KER19800.1 - 0.039 13.6 0.4 0.039 13.6 0.4 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ADK_lid PF05191.14 KER19800.1 - 0.11 12.5 5.5 3 7.9 5.4 2.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 KER19800.1 - 0.21 11.2 15.1 1.4 8.6 1.4 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KER19800.1 - 0.26 11.5 10.3 0.18 11.9 2.0 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KER19800.1 - 1 9.3 8.8 29 4.7 1.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PriA_CRR PF18319.1 KER19800.1 - 2.1 8.4 11.4 0.15 12.1 4.8 2.5 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DUF2318 PF10080.9 KER19800.1 - 2.2 8.5 10.4 1.9 8.7 1.7 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) Lar_restr_allev PF14354.6 KER19800.1 - 4.3 7.8 10.5 0.69 10.3 3.6 2.7 1 1 2 3 3 3 0 Restriction alleviation protein Lar Peptidase_C13 PF01650.18 KER19802.1 - 2e-39 135.7 5.6 1.5e-27 96.8 1.7 3.1 3 0 0 3 3 3 3 Peptidase C13 family FEZ PF07763.13 KER19802.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 FEZ-like protein Peptidase_C13 PF01650.18 KER19803.1 - 1e-18 67.8 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family RT_RNaseH PF17917.1 KER19803.1 - 0.073 13.4 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Peptidase_C13 PF01650.18 KER19804.1 - 2e-71 240.5 12.1 6.7e-38 130.7 0.3 3.1 1 1 2 3 3 3 3 Peptidase C13 family Nudix_hydro PF18290.1 KER19804.1 - 0.026 14.5 0.5 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Nudix hydrolase domain PTRF_SDPR PF15237.6 KER19804.1 - 0.076 12.6 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 PTRF/SDPR family Ribosomal_L19 PF01245.20 KER19804.1 - 0.11 12.5 0.2 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L19 RST PF12174.8 KER19804.1 - 0.18 11.8 2.0 20 5.2 0.2 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain UPF0561 PF10573.9 KER19804.1 - 0.99 9.5 3.1 21 5.2 0.2 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0561 Peptidase_C13 PF01650.18 KER19805.1 - 1.3e-59 201.8 0.1 2e-59 201.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER19805.1 - 1.4e-05 25.2 0.1 3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Caspase domain LpxI_N PF17930.1 KER19805.1 - 0.043 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain Peptidase_C13 PF01650.18 KER19806.1 - 7.7e-28 97.7 0.2 9.1e-28 97.5 0.2 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER19807.1 - 0.00045 19.8 0.2 0.00064 19.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family NOA36 PF06524.12 KER19809.1 - 0.00019 20.8 13.0 0.00035 20.0 13.0 1.4 1 0 0 1 1 1 1 NOA36 protein CENP-B_dimeris PF09026.10 KER19809.1 - 0.0036 17.6 20.6 0.014 15.8 20.6 1.9 1 0 0 1 1 1 1 Centromere protein B dimerisation domain BNIP2 PF12496.8 KER19809.1 - 0.03 14.8 6.9 0.044 14.2 2.2 2.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RXT2_N PF08595.11 KER19809.1 - 0.038 14.0 4.2 0.11 12.5 4.2 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 KER19809.1 - 6.5 5.2 9.1 12 4.3 9.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-HIT PF04438.16 KER19810.1 - 7.1e-09 35.4 6.0 1.2e-08 34.6 6.0 1.4 1 0 0 1 1 1 1 HIT zinc finger PAPA-1 PF04795.12 KER19810.1 - 0.015 16.0 0.5 0.015 16.0 0.5 2.2 2 0 0 2 2 2 0 PAPA-1-like conserved region Smg4_UPF3 PF03467.15 KER19812.1 - 1e-39 136.4 0.1 1.9e-39 135.5 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family LIAS_N PF16881.5 KER19812.1 - 0.071 13.5 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family PLAT PF01477.23 KER19813.1 - 3.4e-05 24.4 0.5 0.00011 22.8 0.1 2.1 2 0 0 2 2 2 1 PLAT/LH2 domain Mod_r PF07200.13 KER19814.1 - 0.039 14.1 17.8 1 9.4 5.7 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein VGPC1_C PF16799.5 KER19814.1 - 0.44 10.5 10.2 4.5 7.3 0.3 3.8 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ZapB PF06005.12 KER19814.1 - 0.53 10.8 32.6 12 6.4 10.5 4.5 1 1 3 4 4 4 0 Cell division protein ZapB YabA PF06156.13 KER19814.1 - 1.2 9.8 26.8 0.91 10.2 2.4 4.3 2 1 1 4 4 4 0 Initiation control protein YabA DUF4407 PF14362.6 KER19814.1 - 2.5 7.4 14.1 5.7 6.2 14.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prp18 PF02840.15 KER19815.1 - 9.2e-37 126.3 0.1 9.2e-37 126.3 0.1 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KER19815.1 - 5.1e-12 45.1 1.3 1.1e-11 44.0 1.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like BppU_IgG PF18667.1 KER19815.1 - 0.035 14.3 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain AMP-binding PF00501.28 KER19816.1 - 0.0001 21.0 0.0 0.00015 20.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M41 PF01434.18 KER19818.1 - 3.4e-57 193.4 0.0 5.9e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KER19818.1 - 3e-41 140.9 0.0 9.2e-41 139.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER19818.1 - 4.8e-10 39.1 0.1 6.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KER19818.1 - 2.9e-06 27.3 0.0 7.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KER19818.1 - 4.3e-05 23.3 0.0 0.00013 21.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KER19818.1 - 0.00034 21.1 2.1 0.0049 17.3 0.2 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KER19818.1 - 0.0021 18.3 1.7 0.041 14.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KER19818.1 - 0.0033 16.7 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KER19818.1 - 0.0054 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KER19818.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KER19818.1 - 0.023 14.1 0.1 0.057 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KER19818.1 - 0.029 14.5 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KER19818.1 - 0.031 14.2 0.8 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 KER19818.1 - 0.036 14.2 0.0 0.15 12.1 0.0 2.1 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KER19818.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KER19818.1 - 0.092 12.3 0.1 3.6 7.1 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KER19818.1 - 0.1 12.1 0.1 0.32 10.5 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KER19818.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KER19818.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KER19818.1 - 0.18 11.5 0.0 0.67 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain UDG PF03167.19 KER19819.1 - 1.7e-20 73.5 0.0 3.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RskA PF10099.9 KER19819.1 - 0.00025 21.4 6.2 0.00049 20.4 6.2 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Glyco_hydro_99 PF16317.5 KER19819.1 - 0.043 12.9 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 99 TFIIA PF03153.13 KER19819.1 - 0.43 10.5 16.9 0.69 9.8 16.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.6 KER19819.1 - 1.9 9.0 6.2 16 6.0 6.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Acetyltransf_1 PF00583.25 KER19822.1 - 3.1e-15 56.4 0.0 3.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER19822.1 - 2.6e-11 43.6 0.1 3.2e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KER19822.1 - 4.7e-09 36.6 0.0 6.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER19822.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KER19822.1 - 0.0047 17.6 0.0 0.0064 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KER19822.1 - 0.0075 16.4 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KER19822.1 - 0.015 14.7 0.9 0.019 14.5 0.1 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KER19822.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Glycoprot_B_PH2 PF17417.2 KER19822.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain DUF2457 PF10446.9 KER19823.1 - 0.0057 15.9 36.6 0.0065 15.7 36.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 KER19823.1 - 0.007 14.7 18.2 0.0067 14.7 18.2 1.0 1 0 0 1 1 1 1 Nop14-like family DNA_pol_phi PF04931.13 KER19823.1 - 0.023 12.9 29.9 0.023 12.8 29.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER19823.1 - 0.063 12.7 21.7 0.067 12.6 21.7 1.0 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KER19823.1 - 0.063 12.5 10.2 0.068 12.4 10.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.10 KER19823.1 - 0.22 11.8 5.4 0.25 11.7 5.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CNDH2_C PF16858.5 KER19823.1 - 0.22 11.3 10.3 0.22 11.3 10.3 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 KER19823.1 - 0.26 9.7 16.9 0.26 9.7 16.9 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 KER19823.1 - 0.33 9.2 19.3 0.35 9.1 19.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KER19823.1 - 0.4 10.5 17.4 0.48 10.3 17.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Slu7 PF11708.8 KER19823.1 - 0.53 10.0 12.8 0.62 9.8 12.8 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor BUD22 PF09073.10 KER19823.1 - 0.84 8.9 19.1 0.87 8.9 19.1 1.0 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 KER19823.1 - 0.95 7.2 6.6 1 7.1 6.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop53 PF07767.11 KER19823.1 - 1.1 8.6 11.0 1.3 8.4 11.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.12 KER19823.1 - 1.1 8.5 30.9 1.7 7.9 30.9 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 KER19823.1 - 1.4 8.2 16.9 1.5 8.1 16.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FYDLN_acid PF09538.10 KER19823.1 - 1.7 9.3 29.0 2.4 8.9 29.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) eIF-3c_N PF05470.12 KER19823.1 - 2 6.7 10.6 1.9 6.7 10.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RPN2_C PF18004.1 KER19823.1 - 2.2 8.2 4.8 2.6 8.0 4.8 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 KER19823.1 - 2.7 7.7 11.6 3.6 7.3 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2796 PF10986.8 KER19823.1 - 4.3 7.3 8.0 5.1 7.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SAPS PF04499.15 KER19823.1 - 5 5.8 6.7 5 5.8 6.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.13 KER19823.1 - 5.6 5.4 14.8 7.2 5.1 14.8 1.3 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.10 KER19823.1 - 6.2 6.1 11.2 7.3 5.9 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Osteopontin PF00865.18 KER19823.1 - 10 5.5 31.4 11 5.4 31.4 1.1 1 0 0 1 1 1 0 Osteopontin Rep_fac_C PF08542.11 KER19824.1 - 1.1e-19 70.6 0.0 2.9e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KER19824.1 - 1.2e-17 64.2 0.0 9e-17 61.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KER19824.1 - 8.6e-15 55.3 0.0 1.8e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KER19824.1 - 1.3e-07 31.8 0.1 6.2e-07 29.5 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KER19824.1 - 5.6e-06 26.7 0.1 2.1e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KER19824.1 - 3.1e-05 24.0 0.0 0.12 12.4 0.0 2.2 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KER19824.1 - 3.4e-05 23.8 0.1 0.00061 19.7 0.0 2.2 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER19824.1 - 8.4e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KER19824.1 - 0.00014 22.3 0.0 0.00063 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KER19824.1 - 0.00021 21.3 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KER19824.1 - 0.00046 20.5 0.0 0.0014 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain DEAD PF00270.29 KER19824.1 - 0.00061 19.6 0.2 0.0044 16.8 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KER19824.1 - 0.00075 19.5 0.0 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KER19824.1 - 0.0008 19.2 0.1 0.0027 17.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KER19824.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KER19824.1 - 0.0019 18.0 0.3 0.0032 17.3 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KER19824.1 - 0.0026 18.1 0.2 0.053 13.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KER19824.1 - 0.0048 16.6 0.1 0.039 13.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 KER19824.1 - 0.0078 15.6 0.0 0.58 9.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KER19824.1 - 0.013 14.8 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KER19824.1 - 0.017 14.6 0.1 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KER19824.1 - 0.025 14.0 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 KER19824.1 - 0.029 13.1 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain T2SSE PF00437.20 KER19824.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KER19824.1 - 0.046 13.5 0.0 0.21 11.3 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein Doppel PF11466.8 KER19824.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Prion-like protein Doppel STOP PF05217.12 KER19825.1 - 0.0071 16.6 8.1 0.0071 16.6 8.1 5.9 7 0 0 7 7 7 1 STOP protein cwf18 PF08315.12 KER19826.1 - 4.4e-33 114.8 2.0 6.7e-33 114.2 2.0 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Pkinase_Tyr PF07714.17 KER19827.1 - 2.6e-27 95.8 0.0 1.4e-25 90.1 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER19827.1 - 1.8e-23 83.2 0.0 3.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MULE PF10551.9 KER19827.1 - 4.4e-21 75.1 0.0 8.9e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 KER19827.1 - 0.025 15.3 0.1 0.058 14.1 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain WRKY PF03106.15 KER19827.1 - 0.049 13.9 1.4 0.11 12.8 1.4 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain APH PF01636.23 KER19827.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM154 PF15102.6 KER19827.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family CCER1 PF15482.6 KER19828.1 - 0.027 14.4 0.2 0.031 14.2 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Solute_trans_a PF03619.16 KER19829.1 - 1.2e-90 303.7 18.7 1.6e-90 303.2 18.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha HEAT PF02985.22 KER19831.1 - 3.6e-07 29.9 8.5 0.014 15.6 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KER19831.1 - 0.0025 18.3 2.3 0.048 14.2 0.0 3.8 3 1 1 4 4 4 2 HEAT-like repeat TAF6_C PF07571.13 KER19831.1 - 0.0065 16.8 0.6 12 6.3 0.0 3.9 2 1 2 4 4 4 2 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KER19831.1 - 0.025 14.1 0.1 0.2 11.2 0.0 2.4 3 0 0 3 3 3 0 CLASP N terminal TniQ PF06527.11 KER19833.1 - 0.15 12.7 2.5 26 5.5 0.0 3.2 3 1 0 3 3 3 0 TniQ zf-C2H2 PF00096.26 KER19837.1 - 4.9e-16 58.2 41.5 1.5e-05 25.1 1.3 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER19837.1 - 5.5e-12 45.4 45.2 0.0026 18.4 1.6 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER19837.1 - 8e-10 38.7 30.7 0.0058 17.0 4.5 5.9 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KER19837.1 - 0.0011 19.3 22.4 0.003 17.8 5.8 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon Ta0938 PF11494.8 KER19837.1 - 0.0027 18.0 2.8 0.39 11.0 0.2 2.4 2 0 0 2 2 2 2 Ta0938 Zn-ribbon_8 PF09723.10 KER19837.1 - 0.0036 17.4 19.1 0.041 14.0 3.1 4.2 4 2 0 4 4 3 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 KER19837.1 - 0.0089 16.7 17.6 0.9 10.2 0.1 4.3 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KER19837.1 - 0.0091 15.6 19.2 0.73 9.5 0.1 5.0 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KER19837.1 - 0.028 14.8 27.4 0.041 14.3 0.3 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KER19837.1 - 0.038 13.6 1.2 0.038 13.6 1.2 4.0 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Spt46 PF17734.1 KER19837.1 - 0.041 13.7 1.2 0.041 13.7 1.2 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 zf-C2H2_jaz PF12171.8 KER19837.1 - 0.054 13.8 0.6 0.054 13.8 0.6 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER19837.1 - 0.059 13.4 0.9 0.059 13.4 0.9 5.7 5 1 0 5 5 5 0 C2H2-type zinc finger MTHFR_C PF12225.8 KER19837.1 - 1.3 8.8 13.0 0.28 10.8 1.7 3.9 2 1 2 4 4 4 0 Methylene-tetrahydrofolate reductase C terminal DZR PF12773.7 KER19837.1 - 6.3 6.9 23.1 2.1 8.5 9.0 3.7 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KER19837.1 - 7 6.5 15.2 9.4 6.1 0.0 4.6 4 0 0 4 4 4 0 zinc-ribbon domain Ion_trans_N PF08412.10 KER19839.1 - 1.1e-24 85.8 0.2 2.7e-24 84.5 0.2 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 KER19839.1 - 6.4e-24 84.5 18.8 1.4e-23 83.4 18.8 1.5 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KER19839.1 - 1.7e-19 69.6 0.0 3.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KER19839.1 - 0.0011 18.8 0.2 0.0031 17.5 0.2 1.9 1 0 0 1 1 1 1 Ion channel Na_K-ATPase PF00287.18 KER19840.1 - 3.8e-39 134.6 1.4 5.1e-39 134.1 1.4 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain GST_C_2 PF13410.6 KER19841.1 - 4.2e-08 33.1 0.0 9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RVT_1 PF00078.27 KER19841.1 - 4.1e-07 29.7 0.1 9.4e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GST_C_3 PF14497.6 KER19841.1 - 0.00039 20.6 0.0 0.0009 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER19841.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alpha_E1_glycop PF01589.16 KER19842.1 - 0.058 12.1 0.1 0.063 11.9 0.1 1.0 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein Phage_G PF02306.15 KER19842.1 - 0.058 13.1 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Major spike protein (G protein) ECH_1 PF00378.20 KER19843.1 - 6.3e-37 127.2 0.6 9.7e-37 126.6 0.6 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER19843.1 - 7.8e-21 74.9 0.1 1.7e-18 67.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase VEK-30 PF12107.8 KER19843.1 - 0.088 12.7 0.4 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway zf-MYND PF01753.18 KER19844.1 - 4.5e-05 23.4 10.7 4.5e-05 23.4 10.7 3.0 3 0 0 3 3 3 1 MYND finger Dynamin_M PF01031.20 KER19845.1 - 7.2e-101 337.2 0.3 1.4e-100 336.2 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KER19845.1 - 1.7e-54 184.4 0.0 4.3e-54 183.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KER19845.1 - 4.8e-32 110.0 1.7 9.5e-32 109.0 1.7 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KER19845.1 - 0.0017 18.4 0.0 0.0079 16.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KER19845.1 - 0.087 13.2 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Baculo_PEP_C PF04513.12 KER19845.1 - 0.12 12.4 0.5 4.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FtsK_SpoIIIE PF01580.18 KER19845.1 - 0.14 11.5 0.2 3.5 6.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynein_attach_N PF15867.5 KER19849.1 - 3e-27 94.3 0.0 6.9e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 KER19849.1 - 6.9e-11 42.5 0.3 1.7e-10 41.3 0.3 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Antigen_Bd37 PF11641.8 KER19849.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Rhomboid PF01694.22 KER19850.1 - 1.3e-36 125.9 9.4 1.3e-36 125.9 9.4 1.8 2 0 0 2 2 2 1 Rhomboid family EF-hand_7 PF13499.6 KER19850.1 - 0.017 15.5 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KER19850.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair DUF4311 PF14188.6 KER19850.1 - 0.035 13.9 1.0 0.063 13.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) SirB PF04247.12 KER19850.1 - 0.043 13.9 1.9 0.1 12.7 1.9 1.6 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB EF-hand_1 PF00036.32 KER19850.1 - 0.078 12.6 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 EF hand SPT_ssu-like PF11779.8 KER19850.1 - 0.59 9.8 7.4 0.44 10.2 3.6 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like Collagen PF01391.18 KER19856.1 - 1.8e-194 629.7 741.4 6.6e-10 38.6 23.6 30.5 6 6 18 25 25 25 23 Collagen triple helix repeat (20 copies) C4 PF01413.19 KER19856.1 - 5.8e-64 213.4 3.4 2e-32 111.8 0.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen RPT PF13446.6 KER19858.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 A repeated domain in UCH-protein PIG-H PF10181.9 KER19859.1 - 1.9e-05 24.4 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component 7tm_1 PF00001.21 KER19860.1 - 4e-15 55.9 32.9 5.4e-12 45.6 16.3 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) zf-H3C2 PF16721.5 KER19860.1 - 0.095 13.1 0.1 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding WD40 PF00400.32 KER19861.1 - 2.6e-14 53.4 8.8 0.0022 18.8 0.2 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat BTB PF00651.31 KER19862.1 - 1.6e-13 50.8 0.7 5.6e-13 49.1 0.3 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 KER19862.1 - 7.1e-06 26.1 2.4 0.00028 20.9 0.5 3.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch Crust_neuro_H PF03858.13 KER19863.1 - 0.0015 19.3 2.7 2.3 9.1 0.2 2.9 2 0 0 2 2 2 2 Crustacean neurohormone H Sof1 PF04158.14 KER19863.1 - 0.022 15.0 1.9 14 6.0 0.0 3.4 3 0 0 3 3 3 0 Sof1-like domain Baculo_PEP_C PF04513.12 KER19863.1 - 0.046 13.8 0.1 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glu_dehyd_C PF16912.5 KER19863.1 - 0.088 12.3 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Reo_sigmaC_M PF17750.1 KER19863.1 - 1.1 9.2 6.6 13 5.7 0.2 3.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein triple beta spiral Death PF00531.22 KER19865.1 - 9.8e-05 22.4 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 Death domain MOZART1 PF12554.8 KER19865.1 - 0.00023 20.9 0.3 0.99 9.2 0.0 2.6 2 0 0 2 2 2 2 Mitotic-spindle organizing gamma-tubulin ring associated DUF104 PF01954.16 KER19865.1 - 0.00051 20.4 2.3 1.1 9.7 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function DUF104 Glyco_hydro_49 PF03718.13 KER19865.1 - 0.014 15.4 0.0 9.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 ZU5 PF00791.20 KER19865.1 - 0.035 14.5 0.1 0.16 12.3 0.1 2.2 2 0 0 2 2 2 0 ZU5 domain adh_short PF00106.25 KER19866.1 - 1.2e-27 96.7 0.0 7.3e-16 58.2 0.0 2.9 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KER19866.1 - 2.4e-16 60.0 0.0 3.1e-10 40.0 0.0 2.7 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KER19866.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KER19866.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KER19866.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding ApbA PF02558.16 KER19866.1 - 0.02 14.6 0.1 0.051 13.2 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 KER19866.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PurA PF04845.13 KER19867.1 - 1.3e-65 220.8 0.1 1.6e-65 220.5 0.1 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 KER19867.1 - 1.9e-06 28.1 0.4 0.15 12.2 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) Peptidase_C13 PF01650.18 KER19868.1 - 6.2e-18 65.2 0.1 7.1e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Proteasome PF00227.26 KER19870.1 - 8.4e-37 126.5 0.1 1.1e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KER19871.1 - 1.9e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Alpha-amylase PF00128.24 KER19872.1 - 6.6e-06 25.9 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, catalytic domain PrgI PF12666.7 KER19872.1 - 0.024 15.4 0.4 0.075 13.7 0.4 1.8 1 0 0 1 1 1 0 PrgI family protein Pkinase PF00069.25 KER19873.1 - 8.5e-57 192.5 0.1 2.4e-56 191.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KER19873.1 - 4.8e-40 137.9 0.0 8.9e-25 87.8 0.0 2.6 3 0 0 3 3 3 2 CNH domain Pkinase_Tyr PF07714.17 KER19873.1 - 1e-38 133.1 0.0 1.6e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER19873.1 - 0.0035 16.2 0.0 0.0074 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER19873.1 - 0.0043 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Nop14 PF04147.12 KER19873.1 - 2.6 6.1 9.9 5.1 5.2 9.9 1.4 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L12 PF00542.19 KER19876.1 - 5.8e-21 74.6 5.1 5.8e-21 74.6 5.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KER19876.1 - 7.1e-08 32.0 0.3 7.1e-08 32.0 0.3 2.8 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain DUF305 PF03713.13 KER19876.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF305) YL1_C PF08265.11 KER19877.1 - 2e-08 33.9 0.1 3.6e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-C2H2 PF00096.26 KER19878.1 - 5e-14 51.9 20.2 0.00019 21.7 3.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER19878.1 - 1.1e-12 47.7 20.8 2.3e-07 30.9 0.8 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER19878.1 - 2.1e-07 31.2 19.2 0.01 16.6 2.4 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER19878.1 - 2.5 8.5 5.3 17 5.8 5.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 KER19878.1 - 6 7.6 10.8 0.1 13.2 1.5 2.9 3 1 0 3 3 3 0 FOXP coiled-coil domain LAMTOR5 PF16672.5 KER19879.1 - 0.096 12.6 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 zf-GRF PF06839.12 KER19879.1 - 2.3 8.4 5.9 18 5.5 0.4 2.4 2 0 0 2 2 2 0 GRF zinc finger PIH1 PF08190.12 KER19880.1 - 2e-32 112.0 0.0 3e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 KER19880.1 - 3.7e-13 49.7 0.1 7e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain DREV PF05219.12 KER19882.1 - 4.3e-62 209.6 0.0 5.3e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 KER19882.1 - 1.9e-10 40.8 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER19882.1 - 2e-09 37.9 0.0 4.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER19882.1 - 8.4e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER19882.1 - 1.2e-07 32.4 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER19882.1 - 0.00038 20.3 0.0 0.0078 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KER19882.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 KER19882.1 - 0.033 13.8 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 KER19882.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCI PF01399.27 KER19884.1 - 7.5e-13 48.9 0.1 3.2e-12 46.9 0.1 2.2 2 0 0 2 2 2 1 PCI domain TPR_10 PF13374.6 KER19884.1 - 0.021 14.7 0.3 12 5.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.19 KER19885.1 - 2e-27 96.1 0.0 3.2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Spuma_A9PTase PF03539.14 KER19886.1 - 0.015 15.5 0.1 0.019 15.1 0.1 1.1 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Peptidase_A17 PF05380.13 KER19887.1 - 8.8e-28 97.3 0.0 1.3e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF294_C PF10335.9 KER19887.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain DAGK_cat PF00781.24 KER19888.1 - 4.2e-23 81.3 0.0 6.4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Steroid_dh PF02544.16 KER19894.1 - 4.2e-16 59.3 4.4 7.8e-16 58.4 4.4 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PHO4 PF01384.20 KER19894.1 - 0.27 10.3 1.3 0.27 10.3 0.8 1.4 1 1 0 1 1 1 0 Phosphate transporter family KLRAQ PF10205.9 KER19896.1 - 2.9 8.2 11.5 0.29 11.4 0.7 2.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4550 PF15084.6 KER19897.1 - 4.8e-29 100.6 0.0 1.1e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4550) AAA PF00004.29 KER19898.1 - 5.1e-39 133.7 0.0 7.8e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KER19898.1 - 6.1e-08 32.6 0.0 1.7e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KER19898.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER19898.1 - 6.7e-05 22.9 0.4 0.0003 20.8 0.4 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER19898.1 - 0.00027 21.2 1.4 0.038 14.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KER19898.1 - 0.0003 21.2 0.2 0.081 13.3 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KER19898.1 - 0.0045 17.1 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KER19898.1 - 0.0049 16.1 0.1 0.014 14.7 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KER19898.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KER19898.1 - 0.033 13.6 0.6 0.11 11.9 0.2 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KER19898.1 - 0.066 13.0 0.1 0.63 9.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 KER19898.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KER19898.1 - 0.15 11.4 0.1 12 5.2 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KER19898.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KER19898.1 - 0.28 10.5 1.1 5.5 6.3 0.2 2.2 1 1 1 2 2 2 0 KaiC zf_CCCH_4 PF18345.1 KER19899.1 - 1.1e-15 57.1 29.7 3.3e-08 33.3 3.4 3.6 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KER19899.1 - 6.7e-15 54.6 27.4 5.1e-06 26.3 3.9 3.5 2 1 1 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER19899.1 - 3.4e-08 33.1 24.6 0.0004 20.1 4.8 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 KER19899.1 - 6.9e-05 23.5 22.4 0.0061 17.2 2.5 3.8 2 1 2 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 KER19899.1 - 0.00019 21.6 16.8 0.0014 18.8 4.9 3.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KER19899.1 - 0.0039 17.6 4.0 0.0039 17.6 4.0 4.3 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger UCH PF00443.29 KER19901.1 - 1.6e-40 139.3 0.0 2e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER19901.1 - 7.2e-08 32.4 0.3 0.0041 16.7 0.5 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 KER19902.1 - 0.00091 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER19902.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER19902.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain CopK PF11525.8 KER19903.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein K TP53IP5 PF15331.6 KER19904.1 - 0.54 10.4 4.9 0.96 9.6 4.9 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF1387 PF07139.11 KER19904.1 - 3.2 7.4 11.7 2.3 7.8 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1387) RVT_1 PF00078.27 KER19905.1 - 2e-09 37.3 0.0 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_PH PF01138.21 KER19906.1 - 1.4e-19 70.9 0.0 2.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 OrsD PF12013.8 KER19907.1 - 0.012 16.0 0.5 0.018 15.5 0.5 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D RIC1 PF07064.13 KER19908.1 - 1.4e-69 234.3 0.1 3.6e-69 233.0 0.1 1.7 1 0 0 1 1 1 1 RIC1 Filament PF00038.21 KER19910.1 - 3.4e-51 174.7 63.1 7.3e-51 173.6 63.1 1.5 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KER19910.1 - 1e-12 48.4 0.0 1.9e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Tup_N PF08581.10 KER19910.1 - 0.00035 20.8 9.2 0.00035 20.8 9.2 5.8 2 2 3 5 5 5 1 Tup N-terminal DUF3137 PF11335.8 KER19910.1 - 0.018 15.0 1.7 0.05 13.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) DUF4200 PF13863.6 KER19910.1 - 0.02 15.3 15.4 0.02 15.3 15.4 4.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF4094 PF13334.6 KER19910.1 - 0.022 15.2 2.8 0.022 15.2 2.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Pox_A_type_inc PF04508.12 KER19910.1 - 0.4 10.6 23.9 0.17 11.8 1.9 5.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat GAS PF13851.6 KER19910.1 - 2.1 7.7 51.6 0.6 9.4 8.9 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KER19910.1 - 4.6 6.0 47.7 4.9 5.9 17.1 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 KER19910.1 - 6 6.6 25.7 0.13 12.0 4.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) FPP PF05911.11 KER19910.1 - 6.2 4.9 48.5 0.16 10.1 17.1 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil FAM184 PF15665.5 KER19910.1 - 6.4 6.5 53.2 2.9 7.6 5.1 4.0 1 1 3 4 4 4 0 Family with sequence similarity 184, A and B Baculo_PEP_C PF04513.12 KER19910.1 - 6.7 6.8 12.9 1.7 8.7 0.5 3.8 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 KER19910.1 - 8.1 6.2 17.1 8.6 6.1 4.8 2.8 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Metallophos PF00149.28 KER19911.1 - 3.2e-11 44.1 2.2 5.9e-11 43.2 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase rve PF00665.26 KER19911.1 - 7.2e-10 39.1 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Lectin_C PF00059.21 KER19911.1 - 1.2e-08 35.7 0.1 3.1e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 Lectin C-type domain Tetraspanin PF00335.20 KER19913.1 - 5.6e-16 59.0 1.4 6.3e-16 58.8 1.4 1.0 1 0 0 1 1 1 1 Tetraspanin family SH2 PF00017.24 KER19914.1 - 0.11 12.6 0.1 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 SH2 domain Pkinase PF00069.25 KER19916.1 - 6e-51 173.3 0.0 2.1e-50 171.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER19916.1 - 4.2e-22 78.7 0.1 9e-21 74.3 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER19916.1 - 0.00036 19.9 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KER19916.1 - 0.0037 17.2 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SAM_PNT PF02198.16 KER19916.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain QLQ PF08880.11 KER19916.1 - 0.047 13.4 1.3 0.16 11.7 0.0 2.6 3 0 0 3 3 3 0 QLQ Tecti-min-caps PF09300.10 KER19920.1 - 5.3e-05 23.2 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 2 Tectiviridae, minor capsid HTH_Tnp_ISL3 PF13542.6 KER19920.1 - 0.0028 17.0 0.3 2.9 7.4 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 VPR PF00522.18 KER19920.1 - 0.0081 16.2 0.0 5.8 7.0 0.0 2.2 2 0 0 2 2 2 2 VPR/VPX protein FerA PF08165.11 KER19920.1 - 0.0084 16.0 0.1 4.7 7.2 0.0 3.1 3 0 0 3 3 3 1 FerA (NUC095) domain PHD20L1_u1 PF16660.5 KER19920.1 - 0.022 15.5 4.9 3 8.7 0.2 2.5 2 1 0 2 2 2 0 PHD finger protein 20-like protein 1 Raptor_N PF14538.6 KER19920.1 - 0.033 14.1 1.7 0.91 9.5 0.2 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Zmiz1_N PF18028.1 KER19920.1 - 0.036 14.4 0.1 6.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF1256 PF06866.11 KER19920.1 - 0.15 11.5 0.0 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) WD40 PF00400.32 KER19921.1 - 6.3e-06 26.8 8.3 0.042 14.7 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat OST3_OST6 PF04756.13 KER19924.1 - 4.2e-61 206.9 0.2 7.7e-60 202.7 0.2 2.1 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KER19924.1 - 0.042 13.9 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.27 KER19926.1 - 4.4e-59 196.4 0.0 3.9e-20 71.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF637 PF04830.13 KER19926.1 - 0.049 13.4 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Possible hemagglutinin (DUF637) Tim17 PF02466.19 KER19926.1 - 0.079 13.3 0.2 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 KER19926.1 - 0.15 11.2 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease SecY PF00344.20 KER19928.1 - 1.1e-75 254.7 18.3 2.5e-69 233.9 12.8 2.0 2 0 0 2 2 2 2 SecY translocase Plug_translocon PF10559.9 KER19928.1 - 9.6e-15 54.1 0.0 3.1e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 KER19928.1 - 7.9 6.4 9.3 0.66 9.9 0.7 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) Ribosomal_S11 PF00411.19 KER19930.1 - 3.4e-44 149.7 1.1 4.7e-44 149.3 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 TDP43_N PF18694.1 KER19932.1 - 2.8e-27 94.4 0.0 5.5e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KER19932.1 - 6.7e-25 86.7 0.0 1e-12 47.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER19932.1 - 0.0078 16.3 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif RL PF17797.1 KER19932.1 - 0.11 12.5 0.0 29 4.7 0.0 2.8 3 0 0 3 3 3 0 RL domain RRM_1 PF00076.22 KER19934.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.20 KER19939.1 - 0.00014 21.6 0.0 0.0004 20.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER19939.1 - 0.0049 16.2 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KER19939.1 - 0.0077 16.8 0.1 0.0099 16.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KER19939.1 - 0.034 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Histone PF00125.24 KER19940.1 - 1.7e-07 31.7 0.0 2.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER19940.1 - 0.0097 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vps52 PF04129.12 KER19943.1 - 4e-120 401.9 0.0 6.7e-111 371.5 0.0 2.4 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 KER19943.1 - 4e-14 52.0 1.2 1.8e-11 43.2 0.6 3.4 2 2 1 3 3 3 1 Exocyst complex component Sec3 Baculo_PEP_C PF04513.12 KER19943.1 - 0.0097 15.9 4.0 0.019 15.0 0.3 3.2 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Med7 PF05983.11 KER19943.1 - 0.035 14.2 1.3 0.14 12.3 0.1 2.4 2 0 0 2 2 2 0 MED7 protein OSK PF17182.4 KER19943.1 - 0.057 12.7 0.9 0.12 11.6 0.9 1.5 1 0 0 1 1 1 0 OSK domain THOC7 PF05615.13 KER19943.1 - 0.11 12.8 3.3 0.98 9.7 1.0 2.7 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1664 PF07889.12 KER19943.1 - 0.23 11.5 0.5 0.88 9.6 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NIF PF03031.18 KER19944.1 - 1.3e-32 112.7 0.0 5.7e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase NUP50 PF08911.11 KER19947.1 - 4.1e-14 53.0 0.5 1.2e-13 51.6 0.5 1.8 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KER19947.1 - 3.8e-10 40.1 0.0 1.7e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 RanBP1 domain Cnn_1N PF07989.11 KER19949.1 - 1.5e-05 25.1 1.8 1.5e-05 25.1 1.8 10.0 6 4 3 9 9 8 1 Centrosomin N-terminal motif 1 EcsC PF12787.7 KER19949.1 - 0.00035 20.3 0.0 1.2 8.8 2.0 3.2 2 1 0 2 2 2 2 EcsC protein family CENP-F_leu_zip PF10473.9 KER19949.1 - 0.0014 18.7 112.7 0.02 14.9 11.0 8.2 4 2 4 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KER19949.1 - 0.0029 16.5 7.0 0.0029 16.5 7.0 6.5 4 2 3 7 7 7 5 Spc7 kinetochore protein AAA_13 PF13166.6 KER19949.1 - 0.0034 16.1 5.5 0.0034 16.1 5.5 5.2 4 1 1 5 5 5 2 AAA domain DUF2968 PF11180.8 KER19949.1 - 0.0061 16.2 7.0 0.0061 16.2 7.0 6.6 5 2 1 6 6 6 1 Protein of unknown function (DUF2968) DUF948 PF06103.11 KER19949.1 - 0.0067 16.7 29.4 0.79 10.0 0.3 6.1 6 0 0 6 6 6 3 Bacterial protein of unknown function (DUF948) Nsp1_C PF05064.13 KER19949.1 - 0.039 13.7 0.3 0.039 13.7 0.3 8.0 7 1 1 8 8 8 0 Nsp1-like C-terminal region DUF1664 PF07889.12 KER19949.1 - 0.14 12.2 53.1 0.45 10.6 0.0 7.8 5 2 3 8 8 8 0 Protein of unknown function (DUF1664) FapA PF03961.13 KER19949.1 - 0.93 8.0 65.2 0.0086 14.7 2.9 6.1 4 3 2 6 6 6 0 Flagellar Assembly Protein A Sec23_trunk PF04811.15 KER19949.1 - 2.2 7.8 5.6 0.4 10.2 0.8 2.2 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain GAS PF13851.6 KER19949.1 - 2.3 7.5 96.4 0.091 12.1 7.3 7.0 3 2 4 8 8 8 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KER19949.1 - 3.4 8.1 95.7 0.33 11.4 6.7 6.6 2 2 3 6 6 6 0 Fez1 COX8 PF02285.15 KER19950.1 - 0.0082 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIII RT_RNaseH_2 PF17919.1 KER19952.1 - 1.4e-05 25.0 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 KER19953.1 - 9.7e-45 150.3 0.0 4.7e-19 68.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER19953.1 - 5.5e-05 23.2 0.0 0.67 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KER19953.1 - 0.00082 19.2 0.0 0.035 13.9 0.0 2.8 2 1 0 2 2 2 1 Occluded RNA-recognition motif PapC_C PF13953.6 KER19953.1 - 0.12 12.2 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 PapC C-terminal domain LPP20 PF02169.16 KER19953.1 - 4 7.8 7.3 1.6 9.1 0.3 2.6 2 0 0 2 2 2 0 LPP20 lipoprotein CDC50 PF03381.15 KER19955.1 - 1.4e-46 159.3 1.6 9.7e-25 87.6 0.2 2.0 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family ASPRs PF17641.2 KER19956.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related RVT_1 PF00078.27 KER19962.1 - 9.2e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flag1_repress PF03614.13 KER19962.1 - 0.061 13.1 0.0 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Cwf_Cwc_15 PF04889.12 KER19963.1 - 0.036 13.8 20.3 0.046 13.5 20.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KER19963.1 - 0.041 13.2 19.5 0.053 12.8 19.5 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KER19963.1 - 0.14 12.0 8.4 0.15 11.9 8.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 KER19963.1 - 0.27 10.8 9.9 0.35 10.4 9.9 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KER19963.1 - 0.61 8.2 12.0 0.65 8.1 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KER19963.1 - 0.81 7.9 11.1 0.92 7.7 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KER19963.1 - 0.88 8.9 11.0 0.87 8.9 11.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 KER19963.1 - 1.1 8.2 6.0 0.99 8.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sporozoite_P67 PF05642.11 KER19963.1 - 2.6 6.0 4.6 2.5 6.1 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2076 PF09849.9 KER19963.1 - 3.8 7.5 12.4 4.1 7.4 12.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) BUD22 PF09073.10 KER19963.1 - 4.7 6.4 9.6 4.9 6.4 9.6 1.1 1 0 0 1 1 1 0 BUD22 Pacs-1 PF10254.9 KER19964.1 - 4.5e-51 174.1 0.1 1.9e-16 60.0 0.0 4.8 5 0 0 5 5 5 4 PACS-1 cytosolic sorting protein Arginase PF00491.21 KER19965.1 - 5.9e-36 124.4 0.0 7.4e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 KER19966.1 - 5.8e-66 222.8 0.1 8.6e-66 222.3 0.1 1.2 1 0 0 1 1 1 1 Arginase family RVP PF00077.20 KER19967.1 - 0.0053 17.1 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KER19967.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4722 PF15849.5 KER19967.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) Asp_protease_2 PF13650.6 KER19967.1 - 0.088 13.5 0.1 0.27 11.9 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease TBCC PF07986.12 KER19968.1 - 4.9e-24 84.4 3.4 9.8e-18 64.0 4.5 2.5 2 0 0 2 2 2 2 Tubulin binding cofactor C Transp_Tc5_C PF04236.15 KER19968.1 - 0.044 14.1 1.0 0.1 13.0 1.0 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain tRNA-synt_1 PF00133.22 KER19969.1 - 3.6e-25 88.3 0.0 8.8e-17 60.6 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KER19969.1 - 6.8e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KER19969.1 - 7.5e-08 31.5 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KER19969.1 - 2e-07 30.7 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain COG2 PF06148.11 KER19971.1 - 2e-31 108.8 2.9 2e-31 108.8 2.9 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 KER19971.1 - 6.5e-27 94.4 1.1 2e-26 92.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Bromodomain PF00439.25 KER19971.1 - 5.2e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 KER19971.1 - 0.0025 18.0 1.8 0.0093 16.2 1.8 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 KER19971.1 - 0.022 14.7 5.6 0.077 12.9 5.3 2.3 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KER19971.1 - 0.038 14.2 1.7 0.13 12.5 1.7 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain UPA_2 PF17809.1 KER19971.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 UPA domain C1_1 PF00130.22 KER19971.1 - 0.11 12.4 6.4 0.42 10.5 6.4 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps51 PF08700.11 KER19971.1 - 0.15 12.2 0.9 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 Vps51/Vps67 LRR_4 PF12799.7 KER19972.1 - 0.0025 18.2 0.2 0.16 12.5 0.3 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER19972.1 - 0.46 10.3 2.7 1.6 8.5 0.6 2.8 2 1 1 3 3 3 0 Leucine rich repeat NIPSNAP PF07978.13 KER19973.1 - 1.6e-36 124.6 0.3 1e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP Homeodomain PF00046.29 KER19974.1 - 4.1e-19 68.2 9.8 3e-17 62.2 9.8 2.7 1 1 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER19974.1 - 0.00016 21.5 0.2 0.00052 19.9 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain MIG-14_Wnt-bd PF06664.12 KER19975.1 - 2.7e-77 259.9 13.5 4.3e-77 259.2 13.5 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion End_beta_propel PF12217.8 KER19976.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase HCNGP PF07818.13 KER19978.1 - 1.3e-22 80.2 0.4 3.4e-13 50.1 0.1 2.6 2 0 0 2 2 2 2 HCNGP-like protein KH_1 PF00013.29 KER19979.1 - 1.3e-12 47.3 0.6 3.3e-05 23.6 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_9 PF17904.1 KER19979.1 - 2.6e-10 40.5 0.1 8.2e-10 38.9 0.0 1.9 1 1 1 2 2 2 1 FMRP KH0 domain Tudor_FRX1 PF18336.1 KER19979.1 - 0.03 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain Agenet PF05641.12 KER19979.1 - 0.16 12.5 0.1 0.82 10.2 0.0 2.2 2 0 0 2 2 2 0 Agenet domain V_ATPase_I_N PF18670.1 KER19979.1 - 0.18 12.2 0.2 0.46 10.9 0.2 1.7 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain Sporozoite_P67 PF05642.11 KER19982.1 - 0.0019 16.4 2.6 0.0025 16.0 2.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop14 PF04147.12 KER19982.1 - 0.12 10.6 17.0 0.14 10.4 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Serinc PF03348.15 KER19982.1 - 0.24 10.3 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 KER19982.1 - 0.4 10.6 15.2 0.46 10.4 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 KER19982.1 - 0.4 10.9 30.6 0.62 10.3 30.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KER19982.1 - 0.48 8.5 29.9 0.58 8.2 29.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KER19982.1 - 0.54 9.5 15.0 0.66 9.3 15.0 1.1 1 0 0 1 1 1 0 BUD22 DUF2796 PF10986.8 KER19982.1 - 0.6 10.1 4.3 4.1 7.3 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) TFB6 PF17110.5 KER19982.1 - 1.3 8.8 9.0 1.9 8.2 9.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop53 PF07767.11 KER19982.1 - 1.4 8.2 6.2 1.8 7.9 6.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPP4R2 PF09184.11 KER19982.1 - 1.8 8.1 18.6 2.3 7.8 18.6 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KER19982.1 - 1.8 6.7 16.5 2.2 6.5 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KER19982.1 - 2.3 7.5 28.2 3.4 6.9 28.2 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KER19982.1 - 3.3 7.0 19.4 4.2 6.7 19.4 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 KER19982.1 - 4.5 6.1 13.2 5.8 5.7 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleo_P87 PF07267.11 KER19982.1 - 4.6 6.0 9.1 6.1 5.6 9.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2457 PF10446.9 KER19982.1 - 7 5.7 33.5 9.5 5.2 33.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Claudin_2 PF13903.6 KER19983.1 - 3.5e-14 53.0 6.2 5.5e-14 52.4 6.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KER19983.1 - 4.3e-05 23.5 3.1 0.054 13.4 1.0 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 KER19983.1 - 0.041 14.1 10.2 0.17 12.1 9.8 2.2 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein DUF2448 PF10476.9 KER19983.1 - 0.057 13.3 1.3 0.14 12.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Claudin_3 PF06653.11 KER19983.1 - 0.1 12.5 13.2 0.69 9.8 13.3 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PGG PF13962.6 KER19983.1 - 0.1 12.4 2.1 2.2 8.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function Colicin_V PF02674.16 KER19983.1 - 0.19 11.7 3.2 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 Colicin V production protein DUF5090 PF17009.5 KER19983.1 - 0.38 10.7 1.9 0.5 10.3 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) Clc-like PF07062.12 KER19983.1 - 0.74 9.2 11.1 18 4.7 11.1 2.3 1 1 0 1 1 1 0 Clc-like Amastin PF07344.11 KER19983.1 - 2.4 8.0 12.6 0.26 11.1 6.9 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF4764 PF15961.5 KER19985.1 - 7.9e-11 41.4 14.0 1.5e-07 30.5 2.6 3.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4764) Ntox30 PF15532.6 KER19985.1 - 0.0019 18.5 0.0 0.0065 16.8 0.0 1.9 1 0 0 1 1 1 1 Bacterial toxin 30 zf-C2H2 PF00096.26 KER19985.1 - 0.01 16.2 0.2 0.024 15.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER19985.1 - 0.12 13.3 0.2 0.27 12.2 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger P120R PF08062.11 KER19985.1 - 3.6 8.1 5.5 4.3 7.8 2.8 2.4 2 0 0 2 2 2 0 P120R (NUC006) repeat CUB PF00431.20 KER19987.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 KER19988.1 - 1.6e-43 147.5 0.8 2.8e-24 85.6 0.1 2.0 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 KER19988.1 - 0.077 12.8 1.3 2.5 7.9 0.0 2.6 3 0 0 3 3 3 0 CUB-like domain Chrome_Resist PF09828.9 KER19988.1 - 0.083 13.3 0.0 2.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Chromate resistance exported protein CUB PF00431.20 KER19990.1 - 5.9e-49 165.0 0.0 1.6e-23 83.1 0.0 2.0 2 0 0 2 2 2 2 CUB domain CUB_2 PF02408.20 KER19990.1 - 0.0022 17.8 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 2 CUB-like domain UPF0556 PF10572.9 KER19990.1 - 0.013 15.0 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0556 FBD PF08387.10 KER19990.1 - 0.094 12.6 0.8 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 FBD TPR_14 PF13428.6 KER19991.1 - 9.6e-07 29.1 7.3 0.38 11.7 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER19991.1 - 2.7e-06 27.8 5.0 0.00012 22.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER19991.1 - 1.2e-05 24.9 6.7 0.011 15.5 0.1 3.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER19991.1 - 0.0011 18.8 5.5 0.76 10.0 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER19991.1 - 0.0012 18.7 3.1 0.014 15.5 0.9 4.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER19991.1 - 0.0026 17.9 7.5 0.087 13.0 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER19991.1 - 0.033 14.6 5.8 30 5.3 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER19991.1 - 0.053 13.8 11.4 0.039 14.2 0.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER19991.1 - 0.13 12.6 6.3 7 7.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER19991.1 - 0.62 9.8 10.4 8.2 6.2 0.0 4.6 5 0 0 5 5 5 0 TPR repeat ADK PF00406.22 KER19994.1 - 5.8e-38 130.4 0.0 7.4e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KER19994.1 - 6.9e-29 101.0 0.0 9.2e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KER19994.1 - 7.2e-08 33.0 0.1 1.5e-07 32.0 0.1 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KER19994.1 - 0.00078 19.6 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KER19994.1 - 0.0068 15.7 0.0 0.0085 15.4 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 KER19994.1 - 0.01 15.5 0.7 0.28 10.8 0.2 2.1 2 0 0 2 2 2 0 Thymidylate kinase CoaE PF01121.20 KER19994.1 - 0.015 15.0 0.1 4 7.1 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_19 PF13245.6 KER19994.1 - 0.042 14.2 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KER19994.1 - 0.047 14.1 0.1 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KER19994.1 - 0.087 12.5 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 KER19994.1 - 0.099 11.8 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain FAM60A PF15396.6 KER19995.1 - 2.9e-27 96.0 7.4 2.9e-27 96.0 7.4 2.3 2 0 0 2 2 2 1 Protein Family FAM60A LicD PF04991.13 KER19998.1 - 0.0023 18.1 0.1 0.004 17.3 0.1 1.3 1 0 0 1 1 1 1 LicD family Flu_PB2 PF00604.17 KER19999.1 - 0.0034 15.4 0.1 0.0042 15.1 0.1 1.0 1 0 0 1 1 1 1 Influenza RNA-dependent RNA polymerase subunit PB2 DED PF01335.21 KER20002.1 - 0.00064 20.0 0.1 0.0032 17.7 0.0 2.1 2 0 0 2 2 2 1 Death effector domain TRAM_LAG1_CLN8 PF03798.16 KER20004.1 - 1.6e-38 132.5 28.0 1.9e-38 132.2 28.0 1.1 1 0 0 1 1 1 1 TLC domain MpPF26 PF07666.11 KER20004.1 - 0.019 15.0 0.5 0.051 13.7 0.5 1.7 1 0 0 1 1 1 0 M penetrans paralogue family 26 ATG27 PF09451.10 KER20004.1 - 0.27 11.1 0.7 0.64 9.8 0.1 1.8 2 0 0 2 2 2 0 Autophagy-related protein 27 Vault PF01505.18 KER20005.1 - 0.13 12.5 0.0 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Major Vault Protein repeat domain Bombolitin PF08096.11 KER20005.1 - 0.14 12.5 0.5 28 5.3 0.1 2.4 2 0 0 2 2 2 0 Bombolitin family Ribosomal_S2 PF00318.20 KER20005.1 - 0.22 10.7 0.2 16 4.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S2 FAR1 PF03101.15 KER20008.1 - 0.00036 21.2 1.7 0.00058 20.5 0.2 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain Pkinase PF00069.25 KER20009.1 - 1.9e-76 256.9 0.0 3e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20009.1 - 1.9e-42 145.3 0.0 3.1e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER20009.1 - 1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER20009.1 - 4.5e-06 26.4 0.7 1.3e-05 24.8 0.6 1.8 2 0 0 2 2 2 1 RIO1 family KA1 PF02149.19 KER20009.1 - 7.9e-06 25.6 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KER20009.1 - 0.0076 15.6 0.3 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER20009.1 - 0.018 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER20009.1 - 0.025 13.5 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KER20009.1 - 0.042 13.4 0.1 0.08 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MRP-S34 PF16053.5 KER20010.1 - 3.4e-36 123.8 0.0 5.5e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Peptidase_C2 PF00648.21 KER20011.1 - 4.5e-117 390.3 0.0 5.9e-117 389.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KER20011.1 - 3.1e-43 147.4 0.0 5.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III KRAB PF01352.27 KER20011.1 - 0.14 11.8 0.2 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 KRAB box EF-hand_1 PF00036.32 KER20013.1 - 6.7e-13 47.2 0.3 7.3e-06 25.2 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KER20013.1 - 7.1e-13 47.4 0.4 3.5e-07 29.6 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KER20013.1 - 4e-10 39.4 0.7 1.1e-06 28.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KER20013.1 - 6e-07 29.8 0.4 0.02 15.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER20013.1 - 0.001 18.4 2.8 0.033 13.7 0.3 3.6 4 0 0 4 4 4 1 EF hand DSL PF01414.19 KER20016.1 - 1.8e-13 50.6 4.6 1.8e-13 50.6 4.6 4.7 3 1 0 4 4 4 2 Delta serrate ligand EGF PF00008.27 KER20016.1 - 1.5e-10 41.2 59.6 2.4e-06 27.7 8.5 4.9 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KER20016.1 - 0.00018 22.0 1.9 0.00018 22.0 1.9 6.0 6 0 0 6 6 6 3 Human growth factor-like EGF EGF_2 PF07974.13 KER20016.1 - 0.033 14.6 15.1 0.033 14.6 15.1 6.3 6 1 0 6 6 6 0 EGF-like domain CS PF04969.16 KER20017.1 - 7.2e-18 65.4 0.3 1.7e-17 64.2 0.3 1.6 1 0 0 1 1 1 1 CS domain SRP9-21 PF05486.12 KER20018.1 - 0.039 14.3 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF16 PF01519.16 KER20018.1 - 0.083 13.4 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 zf-Tim10_DDP PF02953.15 KER20020.1 - 1.2e-36 124.1 6.6 3e-24 84.5 0.8 2.1 2 0 0 2 2 2 2 Tim10/DDP family zinc finger NES_C_h PF18208.1 KER20020.1 - 1.9e-05 24.9 1.6 0.073 13.3 1.5 2.2 1 1 1 2 2 2 2 Nicking enzyme C-terminal middle helical domain TIL PF01826.17 KER20020.1 - 0.00022 21.4 2.5 0.081 13.2 0.7 2.2 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain Catalase-rel PF06628.12 KER20020.1 - 0.00099 19.3 0.3 2.6 8.3 0.0 3.0 3 0 0 3 3 3 1 Catalase-related immune-responsive Rsbr_N PF08678.10 KER20020.1 - 0.017 15.2 0.6 4.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Rsbr N terminal LELP1 PF15042.6 KER20020.1 - 0.047 14.1 8.3 1.4 9.3 0.6 2.8 1 1 2 3 3 3 0 Late cornified envelope-like proline-rich protein 1 BCNT PF07572.12 KER20020.1 - 0.076 13.1 0.4 13 6.0 0.1 2.2 2 0 0 2 2 2 0 Bucentaur or craniofacial development Bac_small_YrzI PF09501.10 KER20020.1 - 0.12 12.5 2.6 8.4 6.6 0.4 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) SASP PF00269.20 KER20020.1 - 0.15 12.1 3.1 8 6.6 0.2 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type DUF2786 PF10979.8 KER20020.1 - 0.47 10.4 8.4 5.6 7.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) CARD_2 PF16739.5 KER20020.1 - 0.55 10.3 3.4 5.4 7.1 2.0 2.1 1 1 1 2 2 2 0 Caspase recruitment domain DUF3887 PF13026.6 KER20020.1 - 1.7 9.5 5.9 11 6.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) GA PF01468.17 KER20020.1 - 2.1 8.7 6.1 0.93 9.8 1.1 2.1 2 0 0 2 2 2 0 GA module HSCB_C PF07743.13 KER20020.1 - 4.1 7.9 11.3 10 6.7 1.7 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain GDP_Man_Dehyd PF16363.5 KER20021.1 - 1.6e-148 494.5 0.0 7.2e-129 429.9 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KER20021.1 - 4.3e-70 235.9 0.0 8.8e-70 234.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KER20021.1 - 0.0068 15.5 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KER20021.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FEZ PF07763.13 KER20022.1 - 1.9e-09 37.7 0.1 0.00014 21.7 0.0 3.3 3 0 0 3 3 3 3 FEZ-like protein vATP-synt_E PF01991.18 KER20024.1 - 5.7e-36 123.8 8.1 6.7e-36 123.6 8.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PMSI1 PF15322.6 KER20024.1 - 0.07 12.6 0.5 0.078 12.4 0.5 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative ATP-synt_B PF00430.18 KER20024.1 - 0.1 12.7 12.2 0.42 10.7 0.3 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Exonuc_VII_L PF02601.15 KER20024.1 - 1.4 8.4 10.2 1.6 8.2 10.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Trypsin PF00089.26 KER20026.1 - 7.1e-29 101.2 0.1 3.8e-13 49.8 0.0 3.3 2 1 0 2 2 2 2 Trypsin L_HMGIC_fpl PF10242.9 KER20027.1 - 2.3e-21 76.8 5.0 2.1e-12 47.6 0.6 2.8 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KER20027.1 - 0.0035 17.1 4.9 0.049 13.4 0.1 2.6 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMCCDC2 PF15844.5 KER20027.1 - 0.31 10.9 0.8 0.52 10.2 0.8 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 RRN3 PF05327.11 KER20028.1 - 0.0014 17.3 1.1 0.0015 17.2 1.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KER20028.1 - 0.0034 15.7 2.4 0.0041 15.4 2.4 1.1 1 0 0 1 1 1 1 Nop14-like family Hjc PF01870.18 KER20028.1 - 0.0055 16.7 0.1 0.0085 16.1 0.1 1.2 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) SGT1 PF07093.11 KER20028.1 - 0.0093 14.5 2.1 0.012 14.1 2.1 1.1 1 0 0 1 1 1 1 SGT1 protein PPP4R2 PF09184.11 KER20028.1 - 0.016 14.8 1.9 0.019 14.6 1.9 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KER20028.1 - 0.018 13.4 5.8 0.023 13.0 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KER20028.1 - 0.021 14.3 3.6 0.027 13.9 3.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KER20028.1 - 0.041 12.0 19.0 0.05 11.7 19.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TLP-20 PF06088.11 KER20028.1 - 0.058 13.3 0.6 0.091 12.6 0.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 KER20028.1 - 0.14 11.8 3.5 0.31 10.7 3.5 1.6 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 KER20028.1 - 0.16 11.9 8.3 0.24 11.2 8.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region GP67 PF17634.2 KER20028.1 - 0.27 11.7 24.3 0.49 10.8 24.3 1.4 1 0 0 1 1 1 0 Gene product 67 CENP-B_dimeris PF09026.10 KER20028.1 - 0.28 11.6 22.7 0.61 10.5 22.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KER20028.1 - 0.69 9.6 18.7 1.1 8.9 18.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 KER20028.1 - 0.88 9.6 7.8 1.6 8.7 7.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 KER20028.1 - 1 8.6 7.4 1.3 8.2 7.4 1.1 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 KER20028.1 - 1.7 7.1 10.9 2.1 6.8 10.9 1.1 1 0 0 1 1 1 0 Utp14 protein ANAPC15 PF15243.6 KER20028.1 - 1.9 8.9 16.9 73 3.9 17.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 GCIP PF13324.6 KER20028.1 - 2 7.9 8.2 4.3 6.9 8.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YL1 PF05764.13 KER20028.1 - 2.8 8.0 12.3 4.1 7.5 12.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.9 KER20028.1 - 3.3 6.7 27.8 5 6.2 27.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2722 PF10846.8 KER20028.1 - 8.6 5.2 6.1 11 4.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) E1_DerP2_DerF2 PF02221.15 KER20029.1 - 0.035 14.5 0.0 0.071 13.5 0.0 1.6 1 1 0 1 1 1 0 ML domain E1_DerP2_DerF2 PF02221.15 KER20031.1 - 8.7e-11 42.4 0.1 1.1e-10 42.0 0.1 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 KER20031.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase E1_DerP2_DerF2 PF02221.15 KER20032.1 - 2.3e-10 41.0 0.0 2.7e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 ML domain Cu-oxidase_3 PF07732.15 KER20032.1 - 0.076 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Multicopper oxidase Wzt_C PF14524.6 KER20032.1 - 0.21 11.6 0.0 0.51 10.4 0.0 1.6 2 0 0 2 2 2 0 Wzt C-terminal domain Peptidase_C13 PF01650.18 KER20034.1 - 1.7e-93 312.8 1.0 2.2e-93 312.5 1.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20034.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER20034.1 - 0.0037 16.5 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C25 Peptidase_C13 PF01650.18 KER20035.1 - 2.2e-104 348.5 8.0 4e-96 321.5 4.1 2.9 3 0 0 3 3 3 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER20035.1 - 5.6e-06 26.5 0.3 1.1e-05 25.5 0.2 1.6 1 1 0 1 1 1 1 Caspase domain Sulfotransfer_3 PF13469.6 KER20035.1 - 0.0046 17.4 0.2 3.8 7.8 0.0 2.5 2 0 0 2 2 2 2 Sulfotransferase family Vasohibin PF14822.6 KER20035.1 - 0.049 12.9 0.0 3 7.0 0.0 2.5 2 0 0 2 2 2 0 Vasohibin Xpo1 PF08389.12 KER20037.1 - 9.1e-05 22.6 0.1 0.0051 16.9 0.0 2.9 2 0 0 2 2 2 2 Exportin 1-like protein Radial_spoke PF04712.12 KER20038.1 - 5.2e-160 533.6 5.1 5.2e-160 533.6 5.1 1.5 2 0 0 2 2 2 1 Radial spokehead-like protein C2-set_2 PF08205.12 KER20038.1 - 0.13 12.3 0.2 0.33 11.0 0.2 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain ADK PF00406.22 KER20039.1 - 1.1e-25 90.5 0.0 2.8e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KER20039.1 - 2.1e-10 41.2 0.0 1.5e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain LRR_6 PF13516.6 KER20039.1 - 2.2e-10 39.7 3.2 0.11 12.6 0.1 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 KER20039.1 - 3.3e-06 27.4 13.7 2.9 8.4 0.1 7.1 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KER20039.1 - 0.0016 18.3 2.0 0.045 13.7 0.0 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KER20039.1 - 0.0036 17.2 0.4 0.03 14.2 0.0 2.7 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.33 KER20039.1 - 9.4 7.2 22.0 48 5.1 0.0 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat DUF2045 PF09741.9 KER20040.1 - 7.9e-68 228.3 0.0 1.1e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Proteasome PF00227.26 KER20041.1 - 6.6e-59 198.6 0.0 7.6e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RuvA_C PF07499.13 KER20041.1 - 0.0057 17.1 0.1 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 RuvA, C-terminal domain Hep_core_N PF08290.11 KER20041.1 - 0.66 10.0 2.9 4.4 7.4 0.6 2.9 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger HSP20 PF00011.21 KER20044.1 - 6.6e-26 90.4 0.0 2.9e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KER20044.1 - 2.1e-07 30.4 0.0 6.7e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Pkinase_Tyr PF07714.17 KER20046.1 - 9.7e-37 126.6 0.0 1.6e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 KER20046.1 - 1.6e-35 122.9 0.1 7.1e-35 120.7 0.1 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region Guanylate_cyc PF00211.20 KER20046.1 - 1.4e-34 119.3 0.0 2.6e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 KER20046.1 - 2.4e-33 115.7 0.0 5.7e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 KER20046.1 - 5.3e-05 22.8 0.6 9.2e-05 22.0 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated DUF3939 PF13075.6 KER20046.1 - 0.0029 17.6 0.8 0.0091 16.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3939) Noelin-1 PF12308.8 KER20046.1 - 0.091 12.7 0.3 0.25 11.3 0.3 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein GTP_EFTU PF00009.27 KER20050.1 - 2e-12 47.1 0.1 2.2e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynein_light PF01221.18 KER20051.1 - 0.00041 20.6 0.0 0.00059 20.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Cpta_toxin PF07254.12 KER20053.1 - 0.0002 21.3 5.1 0.18 11.8 0.5 2.2 2 0 0 2 2 2 2 Membrane-bound toxin component of toxin-antitoxin system TMEM138 PF14935.6 KER20053.1 - 0.011 16.4 1.2 5 7.8 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 138 SLC3A2_N PF16028.5 KER20053.1 - 0.064 12.8 9.9 0.54 9.9 0.8 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF2706 PF10913.8 KER20053.1 - 0.13 12.1 0.5 23 4.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) DMA PF03474.14 KER20053.1 - 1.5 8.5 6.1 25 4.6 0.2 3.4 3 0 0 3 3 3 0 DMRTA motif PufQ PF05398.11 KER20053.1 - 2 8.6 10.2 5.6 7.2 1.1 2.4 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF3278 PF11683.8 KER20053.1 - 2.3 8.3 5.4 21 5.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) MRAP PF15183.6 KER20053.1 - 3.7 7.6 5.2 29 4.7 0.5 2.5 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Hydrolase_4 PF12146.8 KER20054.1 - 1.4e-13 50.7 0.0 1.1e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KER20054.1 - 2.9e-07 31.3 0.0 1.7e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KER20054.1 - 6.9e-07 29.2 0.0 0.0062 16.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 KER20054.1 - 2.6e-05 23.3 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 KER20054.1 - 0.00019 21.0 0.0 0.003 17.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KER20054.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KER20054.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KER20054.1 - 0.21 11.4 0.0 1.4 8.7 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PTEN_C2 PF10409.9 KER20057.1 - 7.9e-11 41.9 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DJ-1_PfpI PF01965.24 KER20058.1 - 7.3e-47 159.2 0.5 8.4e-47 159.0 0.5 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family DUF348 PF03990.14 KER20058.1 - 0.11 12.3 1.3 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain GATase_3 PF07685.14 KER20058.1 - 0.16 11.5 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain RRM_1 PF00076.22 KER20059.1 - 2.6e-15 56.0 0.0 4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KER20060.1 - 3.4e-59 200.3 0.0 4.6e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20060.1 - 2e-28 99.4 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER20060.1 - 1.5e-05 25.1 0.2 0.036 14.0 0.1 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KER20060.1 - 0.0011 18.4 0.0 0.035 13.4 0.0 2.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER20060.1 - 0.013 14.4 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KER20060.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KER20060.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SART-1 PF03343.13 KER20061.1 - 6.4e-125 418.1 37.9 6.4e-125 418.1 37.9 2.2 2 1 0 2 2 2 1 SART-1 family RVT_1 PF00078.27 KER20061.1 - 2.4e-18 66.5 0.0 4.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F1F0-ATPsyn_F PF10791.9 KER20061.1 - 0.13 12.7 0.0 0.68 10.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi DcpS_C PF11969.8 KER20062.1 - 1.5e-25 89.9 2.2 2e-25 89.5 2.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KER20062.1 - 9.9e-07 29.4 5.2 2.6e-06 28.1 5.2 1.6 1 1 0 1 1 1 1 HIT domain But2 PF09792.9 KER20062.1 - 0.015 15.7 0.1 0.029 14.8 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.16 KER20063.1 - 1e-36 126.6 39.0 1.1e-33 116.7 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Jnk-SapK_ap_N PF09744.9 KER20065.1 - 0.0047 17.2 19.1 0.11 12.7 6.0 2.6 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 Fur_reg_FbpB PF13040.6 KER20065.1 - 0.063 12.8 2.4 0.11 12.1 0.2 2.5 2 0 0 2 2 2 0 Fur-regulated basic protein B Baculo_PEP_C PF04513.12 KER20065.1 - 0.12 12.4 12.7 0.56 10.2 7.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BORCS7 PF16088.5 KER20065.1 - 0.44 10.8 12.2 0.18 12.1 8.3 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF3450 PF11932.8 KER20065.1 - 0.57 9.4 18.7 1.5 8.1 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 KER20065.1 - 0.87 8.4 8.0 0.97 8.3 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF745 PF05335.13 KER20065.1 - 1.3 8.7 14.7 0.032 14.0 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 KER20065.1 - 1.3 9.1 9.8 0.7 9.9 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KER20065.1 - 1.5 8.4 10.6 2 7.9 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KER20065.1 - 3.2 8.1 13.6 0.72 10.2 2.3 3.2 2 2 1 3 3 3 0 Uncharacterized conserved protein RasGAP_C PF03836.15 KER20065.1 - 3.7 7.7 15.3 5.3 7.2 10.0 2.5 1 1 1 2 2 2 0 RasGAP C-terminus Syntaxin-6_N PF09177.11 KER20065.1 - 6 7.5 11.8 59 4.3 9.9 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KER20065.1 - 6.6 7.1 8.9 14 6.0 1.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4709 PF15821.5 KER20065.1 - 6.9 7.0 15.3 1.4 9.2 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) DUF16 PF01519.16 KER20065.1 - 8.8 6.9 19.1 0.27 11.8 5.0 2.6 1 1 0 2 2 2 0 Protein of unknown function DUF16 Ribonuclease_3 PF00636.26 KER20066.1 - 1.8e-49 166.7 2.0 5.9e-21 75.1 0.1 3.7 3 0 0 3 3 3 3 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KER20066.1 - 6.8e-35 120.0 0.1 4.9e-09 36.4 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like dsrm PF00035.26 KER20066.1 - 8.4e-11 42.4 1.0 1.4e-10 41.7 0.1 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif HSBP1 PF06825.12 KER20067.1 - 0.037 13.9 0.3 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Curto_V3 PF07436.11 KER20067.1 - 0.041 14.3 0.1 1.6 9.1 0.1 2.4 2 1 0 2 2 2 0 Curtovirus V3 protein Mito_carr PF00153.27 KER20069.1 - 9.4e-33 112.0 0.2 6.2e-24 83.7 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein zf-CCHC PF00098.23 KER20071.1 - 4.7e-05 23.3 4.0 0.00012 21.9 4.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KER20071.1 - 0.053 13.3 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KER20071.1 - 0.14 12.0 1.4 0.44 10.4 1.4 1.9 1 0 0 1 1 1 0 Zinc knuckle AIF_C PF14721.6 KER20074.1 - 0.0023 18.3 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2642 PF10842.8 KER20075.1 - 0.029 14.2 0.3 0.088 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Gtr1_RagA PF04670.12 KER20076.1 - 4.2e-29 101.6 0.4 6.7e-29 100.9 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ribosomal_S28e PF01200.18 KER20077.1 - 1.6e-30 104.9 0.6 1.9e-30 104.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e tRNA-synt_1b PF00579.25 KER20078.1 - 6.1e-61 206.3 0.0 2.7e-53 181.2 0.0 2.9 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 KER20078.1 - 5.5e-21 74.5 0.0 2.3e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Putative tRNA binding domain BON PF04972.17 KER20078.1 - 0.032 14.5 0.0 21 5.5 0.0 2.9 3 0 0 3 3 3 0 BON domain zf-C2H2 PF00096.26 KER20080.1 - 2.8e-17 62.1 39.4 7.8e-06 26.1 2.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER20080.1 - 5.3e-17 61.0 37.4 0.0014 19.3 1.1 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER20080.1 - 2.1e-10 40.6 47.0 0.00011 22.5 1.1 7.5 7 2 0 7 7 7 5 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KER20080.1 - 3e-05 24.7 18.5 0.0064 17.2 8.5 3.6 1 1 3 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KER20080.1 - 0.0022 18.2 27.7 0.54 10.6 0.3 4.4 2 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KER20080.1 - 0.0035 17.3 31.7 0.2 11.7 0.4 5.8 5 1 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 KER20080.1 - 0.02 15.3 28.9 1.3 9.5 0.8 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KER20080.1 - 0.04 13.7 25.0 0.096 12.5 0.1 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KER20080.1 - 0.12 12.0 18.0 0.91 9.2 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KER20080.1 - 0.2 12.1 0.2 0.2 12.1 0.2 4.5 1 1 2 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_9 PF14369.6 KER20080.1 - 0.22 11.8 4.8 5.1 7.4 0.0 4.0 3 0 0 3 3 3 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KER20080.1 - 0.72 10.0 22.7 7.5 6.8 0.1 5.4 5 1 0 5 5 5 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 KER20080.1 - 0.8 10.1 23.9 0.11 12.8 3.5 3.8 1 1 3 4 4 4 0 C2H2-type zinc ribbon HalOD2 PF18547.1 KER20080.1 - 1.1 9.2 3.9 2.4 8.1 0.4 3.1 3 1 0 3 3 3 0 Halobacterial output domain 2 XPA_N PF01286.18 KER20080.1 - 1.1 9.3 14.2 32 4.7 3.1 4.4 4 0 0 4 4 4 0 XPA protein N-terminal zf_C2H2_ZHX PF18387.1 KER20080.1 - 1.4 8.6 19.1 1.9 8.2 0.1 4.7 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KER20080.1 - 1.8 8.9 21.8 5.3 7.5 0.4 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 KER20080.1 - 3.4 7.7 12.6 1 9.4 0.4 3.7 3 1 0 3 3 3 0 Adenylate kinase, active site lid DUF445 PF04286.12 KER20081.1 - 1.9e-12 47.7 60.7 2.9e-06 27.4 37.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF445) SecD_SecF PF02355.16 KER20081.1 - 2.6e-09 36.7 58.1 1.8e+04 -41.3 58.1 9.8 1 1 0 1 1 1 0 Protein export membrane protein GerPC PF10737.9 KER20081.1 - 1.9e-07 31.3 70.5 1.8e+04 -30.5 70.5 3.5 1 1 0 1 1 1 0 Spore germination protein GerPC EcsC PF12787.7 KER20081.1 - 2.8e-06 27.2 37.7 1.8e+04 -19.5 37.7 6.5 1 1 0 1 1 1 0 EcsC protein family RHD3 PF05879.12 KER20081.1 - 0.00014 20.2 43.6 0.026 12.7 19.9 2.1 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) YpjP PF14005.6 KER20081.1 - 0.00015 21.8 60.1 1.8e+04 -39.5 60.1 6.7 1 1 0 1 1 1 0 YpjP-like protein Glycoprot_B_PH2 PF17417.2 KER20081.1 - 0.71 10.2 59.3 1.8e+04 -44.1 59.3 9.5 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain PdaC PF13739.6 KER20081.1 - 1.5 9.8 122.8 1.8e+04 -100.6 122.8 12.2 1 1 0 1 1 1 0 Deacetylase PdaC UBA PF00627.31 KER20082.1 - 5.6e-06 26.1 1.7 1e-05 25.3 1.7 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KER20082.1 - 0.015 15.1 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain MSP1_C PF07462.11 KER20082.1 - 8.2 5.0 5.9 11 4.6 5.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Thioredoxin PF00085.20 KER20083.1 - 3.1e-12 46.4 0.0 5.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KER20083.1 - 0.00044 19.7 1.7 0.0023 17.3 0.1 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KER20083.1 - 0.013 16.0 0.1 0.064 13.7 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain CfAFP PF05264.11 KER20083.1 - 0.25 11.3 9.7 0.32 11.0 8.9 1.5 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) Bromodomain PF00439.25 KER20084.1 - 4.1e-27 94.1 0.0 1.1e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 KER20084.1 - 1.7e-22 79.3 10.0 5.3e-06 27.1 0.1 7.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20084.1 - 0.00025 21.3 0.1 14 6.0 0.0 5.3 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Auxin_resp PF06507.13 KER20084.1 - 0.095 13.0 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 Auxin response factor RVT_1 PF00078.27 KER20085.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.26 KER20086.1 - 1.4e-13 50.7 0.1 3.8e-13 49.3 0.0 1.7 1 1 0 2 2 2 1 Ubiquitin-conjugating enzyme PAXNEB PF05625.11 KER20087.1 - 0.0062 15.7 0.2 0.022 13.9 0.0 2.0 3 0 0 3 3 3 1 PAXNEB protein Exo_endo_phos PF03372.23 KER20091.1 - 2.1e-13 50.3 0.0 4.8e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KER20091.1 - 4.1e-13 49.4 0.0 9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain INPP5B_PH PF16776.5 KER20091.1 - 0.001 18.8 0.0 0.0068 16.1 0.0 2.1 2 0 0 2 2 2 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Sulfotransfer_4 PF17784.1 KER20092.1 - 2.3e-60 204.1 0.0 2.6e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER20092.1 - 1.8e-06 28.5 0.1 4.5e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Sulfotransferase family DUF4773 PF15998.5 KER20093.1 - 0.0093 16.5 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) TPH PF13868.6 KER20094.1 - 8.3e-05 21.3 107.6 8.3e-05 21.3 107.6 3.6 2 2 0 1 1 1 1 Trichohyalin-plectin-homology domain Mgr1 PF08602.10 KER20094.1 - 2 7.1 23.2 0.039 12.8 5.1 3.0 1 1 2 3 3 3 0 Mgr1-like, i-AAA protease complex subunit DUF3772 PF12607.8 KER20094.1 - 4.2 7.2 9.7 2.2 8.1 2.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) HLH PF00010.26 KER20096.1 - 8.3e-15 54.5 2.0 1.5e-14 53.7 2.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 KER20096.1 - 3.9e-08 34.5 6.5 7.7e-08 33.6 5.2 2.3 1 1 0 1 1 1 1 Neuronal helix-loop-helix transcription factor DUF1232 PF06803.12 KER20098.1 - 2.6e-07 30.3 7.8 4.7e-07 29.5 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) zf-RING_2 PF13639.6 KER20098.1 - 5.4e-06 26.6 13.5 9.4e-06 25.9 13.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER20098.1 - 0.00013 21.8 8.2 0.0002 21.1 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER20098.1 - 0.00027 20.7 11.4 0.00072 19.4 11.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER20098.1 - 0.00035 20.4 11.2 0.00058 19.7 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER20098.1 - 0.0038 17.2 10.3 0.0085 16.0 10.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KER20098.1 - 0.0038 17.4 11.3 0.0075 16.4 11.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KER20098.1 - 0.0076 16.3 9.6 0.0088 16.1 6.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.11 KER20098.1 - 0.0087 16.0 3.2 0.014 15.3 3.2 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Cys_rich_CPXG PF14255.6 KER20098.1 - 0.089 12.7 0.5 0.089 12.7 0.5 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Prok-RING_4 PF14447.6 KER20098.1 - 0.16 11.9 10.7 0.26 11.2 6.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 KER20099.1 - 4.2e-05 24.2 15.5 0.34 11.9 0.3 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20099.1 - 0.012 15.9 0.0 1.5 9.2 0.0 3.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KER20101.1 - 8.6e-14 51.1 0.0 3.9e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LIM PF00412.22 KER20103.1 - 4e-48 161.5 65.8 1.9e-13 50.4 7.1 5.2 5 0 0 5 5 5 5 LIM domain TNFR_c6 PF00020.18 KER20103.1 - 0.033 14.6 0.7 0.033 14.6 0.7 9.0 5 3 5 10 10 10 0 TNFR/NGFR cysteine-rich region RVT_1 PF00078.27 KER20107.1 - 4.1e-06 26.5 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myosin-VI_CBD PF16521.5 KER20107.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Myosin VI cargo binding domain TAL_FSA PF00923.19 KER20108.1 - 7.2e-61 206.0 0.0 8.2e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Asp PF00026.23 KER20109.1 - 4.5e-08 32.9 0.0 5.3e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Sterol_MT_C PF08498.10 KER20109.1 - 0.027 14.8 0.0 0.87 9.9 0.0 2.2 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Cystatin PF00031.21 KER20110.1 - 0.0021 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Cystatin domain Y_phosphatase PF00102.27 KER20112.1 - 1.2e-48 165.7 0.0 1.4e-27 96.8 0.0 2.7 3 0 0 3 3 3 2 Protein-tyrosine phosphatase fn3 PF00041.21 KER20112.1 - 2.5e-22 79.0 19.2 0.009 16.3 0.4 8.9 8 0 0 8 8 8 6 Fibronectin type III domain DSPc PF00782.20 KER20112.1 - 0.00085 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Peptidase_S8 PF00082.22 KER20114.1 - 1.6e-49 168.8 0.0 9.7e-48 162.9 0.0 2.9 2 1 0 2 2 2 1 Subtilase family TPPII PF12580.8 KER20114.1 - 5.6e-09 35.7 0.0 1.9e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 Tripeptidyl peptidase II Ribonuclease_3 PF00636.26 KER20115.1 - 3e-44 149.9 0.0 7.8e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KER20115.1 - 1.4e-26 93.2 0.0 2.1e-16 60.3 0.1 3.3 2 2 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KER20117.1 - 5.8e-44 149.0 0.0 7.7e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KER20117.1 - 8.3e-22 77.7 0.1 2.5e-13 50.3 0.0 3.5 3 1 0 3 3 3 2 Ribonuclease-III-like AChE_tetra PF08674.10 KER20117.1 - 2.2 8.0 4.7 0.67 9.7 1.2 1.9 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain PAP1 PF08601.10 KER20118.1 - 9.1 5.9 15.0 0.022 14.5 3.1 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 MutS_V PF00488.21 KER20120.1 - 2.3e-60 203.9 0.0 3.6e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KER20120.1 - 3.5e-34 117.4 0.0 6.2e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KER20120.1 - 1.1e-32 113.8 0.1 2.4e-32 112.7 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KER20120.1 - 9.3e-11 41.9 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KER20120.1 - 1.4e-05 25.4 0.1 0.00014 22.1 0.0 2.6 3 0 0 3 3 3 1 MutS domain II Baculo_PEP_C PF04513.12 KER20123.1 - 2.3e-05 24.5 18.8 0.03 14.3 4.0 3.4 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KER20123.1 - 0.0072 16.4 29.7 0.69 10.0 6.4 4.5 1 1 2 4 4 4 2 Protein of unknown function (DUF1664) Tup_N PF08581.10 KER20123.1 - 0.0083 16.4 1.3 0.0083 16.4 1.3 5.3 1 1 4 6 6 6 1 Tup N-terminal Viral_P18 PF04521.13 KER20123.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.6 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Sun2_CC2 PF18580.1 KER20123.1 - 0.023 14.9 1.0 0.023 14.9 1.0 3.9 2 1 1 3 3 3 0 SUN2 coiled coil domain 2 Apolipoprotein PF01442.18 KER20123.1 - 0.039 13.8 38.9 1.9 8.3 9.7 3.3 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain AATF-Che1 PF13339.6 KER20123.1 - 0.055 14.2 23.1 1.1e+04 -3.0 23.1 3.4 1 1 0 1 1 0 0 Apoptosis antagonizing transcription factor SF-assemblin PF06705.11 KER20123.1 - 0.07 12.5 35.7 0.15 11.3 4.8 3.2 1 1 2 3 3 3 0 SF-assemblin/beta giardin TAF6_C PF07571.13 KER20123.1 - 0.086 13.2 1.3 18 5.7 0.1 3.7 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain YtxH PF12732.7 KER20123.1 - 0.22 12.1 7.0 4.2e+02 1.6 7.0 4.3 1 1 0 1 1 1 0 YtxH-like protein DUF16 PF01519.16 KER20123.1 - 0.27 11.7 28.9 0.17 12.4 5.2 3.6 2 1 1 3 3 3 0 Protein of unknown function DUF16 COG2 PF06148.11 KER20123.1 - 0.44 10.6 26.8 1.6 8.9 1.1 4.8 1 1 4 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Golgin_A5 PF09787.9 KER20123.1 - 0.47 9.9 43.7 0.39 10.1 7.1 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF948 PF06103.11 KER20123.1 - 1.1 9.5 18.6 2 8.7 2.0 4.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KER20123.1 - 1.3 7.8 39.9 0.027 13.3 15.2 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KER20123.1 - 1.5 9.0 33.3 2.1 8.5 10.0 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FAST_2 PF08368.12 KER20123.1 - 1.7 9.5 5.6 6.9 7.5 0.2 3.6 3 1 1 4 4 3 0 FAST kinase-like protein, subdomain 2 OmpH PF03938.14 KER20123.1 - 2.4 8.5 34.6 0.7 10.2 8.3 3.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) ApoO PF09769.9 KER20123.1 - 2.4 8.1 12.5 4.5 7.3 0.5 4.2 1 1 4 5 5 5 0 Apolipoprotein O Filament PF00038.21 KER20123.1 - 2.6 7.6 43.6 2.1 7.9 9.7 3.3 1 1 2 3 3 3 0 Intermediate filament protein IFT57 PF10498.9 KER20123.1 - 2.7 6.8 31.4 0.2 10.6 7.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PMC2NT PF08066.12 KER20123.1 - 2.9 8.7 16.5 3.8 8.3 1.5 4.1 1 1 3 4 4 4 0 PMC2NT (NUC016) domain Syntaxin-6_N PF09177.11 KER20123.1 - 3.2 8.3 27.2 9.3 6.9 4.4 4.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal AI-2E_transport PF01594.16 KER20123.1 - 5.3 6.1 6.1 22 4.0 0.7 2.6 1 1 1 3 3 3 0 AI-2E family transporter CHASE6_C PF17150.4 KER20123.1 - 7.1 7.4 8.9 0.41 11.3 0.7 3.1 3 1 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain Cu2_monoox_C PF03712.15 KER20124.1 - 9.9e-26 90.1 1.3 1.3e-25 89.7 0.1 1.7 1 1 1 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KER20124.1 - 2.5e-17 63.3 0.2 4.4e-17 62.5 0.2 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Ribo_biogen_C PF04034.13 KER20125.1 - 5.6e-48 161.9 0.0 8.8e-48 161.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal Methyltransf_23 PF13489.6 KER20125.1 - 1.5e-15 57.5 0.0 2.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER20125.1 - 5.1e-14 52.8 0.0 1.9e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER20125.1 - 1.9e-11 44.5 0.1 2e-07 31.6 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KER20125.1 - 2.9e-09 37.4 0.6 3.6e-07 30.7 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER20125.1 - 3.2e-07 30.3 0.0 9.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KER20125.1 - 8.9e-06 25.2 0.0 0.00025 20.4 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KER20125.1 - 0.06 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Rsm22 PF09243.10 KER20125.1 - 0.063 12.5 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 CheR PF01739.18 KER20125.1 - 0.083 12.4 0.1 6.8 6.1 0.0 2.6 3 0 0 3 3 3 0 CheR methyltransferase, SAM binding domain Spike_NTD PF16451.5 KER20125.1 - 0.11 11.9 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Sulfate_transp PF00916.20 KER20126.1 - 7.9e-24 84.1 1.0 1e-23 83.7 1.0 1.1 1 0 0 1 1 1 1 Sulfate permease family Tim17 PF02466.19 KER20126.1 - 0.012 16.0 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Sulfate_transp PF00916.20 KER20127.1 - 1.2e-74 251.4 13.1 1.7e-74 250.9 13.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KER20127.1 - 1.1e-17 63.7 0.0 2.6e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain BDV_P10 PF06515.11 KER20128.1 - 0.026 14.6 0.6 0.093 12.8 0.6 2.0 1 0 0 1 1 1 0 Borna disease virus P10 protein Myc_target_1 PF15179.6 KER20128.1 - 0.19 11.6 8.4 0.024 14.6 2.8 2.5 2 0 0 2 2 2 0 Myc target protein 1 MAT1 PF06391.13 KER20129.1 - 3.2e-30 105.5 19.3 3.2e-30 105.5 19.3 3.0 3 1 0 3 3 3 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KER20129.1 - 1.4e-05 24.9 4.8 6.1e-05 22.8 4.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1104 PF06518.11 KER20129.1 - 0.058 13.8 0.1 36 4.8 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Met_10 PF02475.16 KER20131.1 - 1.1e-50 172.2 0.0 2.1e-49 168.0 0.0 2.1 1 1 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KER20131.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase RBB1NT PF08169.11 KER20133.1 - 2.4e-08 34.0 0.0 1.2e-07 31.8 0.0 2.3 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.21 KER20133.1 - 3.4e-08 34.0 0.0 1.8e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.8 KER20133.1 - 1.2e-06 28.3 0.0 3.1e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_hydro_56 PF01630.18 KER20133.1 - 0.27 10.2 1.6 16 4.3 0.1 2.5 2 0 0 2 2 2 0 Hyaluronidase TruB_N PF01509.18 KER20136.1 - 8.2e-05 23.0 0.0 0.051 13.9 0.0 2.2 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) E1_DerP2_DerF2 PF02221.15 KER20137.1 - 2.7e-17 63.5 0.4 4.8e-17 62.7 0.4 1.4 1 0 0 1 1 1 1 ML domain PAN_1 PF00024.26 KER20137.1 - 0.0007 19.5 2.1 0.0015 18.5 0.4 2.4 3 0 0 3 3 3 1 PAN domain PAN_3 PF08277.12 KER20137.1 - 0.03 14.1 0.4 0.65 9.9 0.1 2.4 2 0 0 2 2 2 0 PAN-like domain Ribosomal_S7 PF00177.21 KER20138.1 - 1.9e-34 118.5 0.2 2.4e-34 118.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Stathmin PF00836.19 KER20140.1 - 2.5 8.1 9.8 0.053 13.5 2.9 1.9 2 1 0 2 2 2 0 Stathmin family zf_CCCH_4 PF18345.1 KER20141.1 - 0.0036 17.3 5.3 0.0036 17.3 5.3 5.0 6 0 0 6 6 6 1 Zinc finger domain zf-CCCH PF00642.24 KER20141.1 - 0.0041 17.0 0.4 0.0041 17.0 0.4 4.8 5 0 0 5 5 5 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KER20141.1 - 0.01 16.0 9.2 1.6 9.0 3.1 3.4 2 1 1 3 3 3 0 Zinc-finger containing family TEX13 PF15186.6 KER20141.1 - 3.4 7.3 16.5 0.05 13.3 6.6 2.6 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Claudin_3 PF06653.11 KER20142.1 - 0.013 15.5 1.6 0.013 15.5 1.6 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like YdjO PF14169.6 KER20142.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Anoctamin PF04547.12 KER20142.1 - 0.42 9.4 2.8 0.17 10.7 0.1 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel MgtE PF01769.16 KER20142.1 - 6.1 7.2 9.2 2 8.8 2.8 2.3 2 0 0 2 2 2 0 Divalent cation transporter Mpp10 PF04006.12 KER20143.1 - 0.015 13.8 5.9 0.019 13.5 5.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 KER20143.1 - 0.042 12.1 16.0 0.054 11.7 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KER20143.1 - 0.12 11.8 17.1 0.16 11.3 17.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER20143.1 - 0.16 11.3 10.1 0.19 11.0 10.1 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KER20143.1 - 0.49 8.9 15.2 0.69 8.4 15.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 KER20143.1 - 1.8 8.1 13.1 2.4 7.7 13.1 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KER20143.1 - 4 5.6 15.8 5.9 5.1 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_4 PF13894.6 KER20144.1 - 4.6e-05 23.9 35.4 0.85 10.6 0.8 8.2 8 0 0 8 8 8 4 C2H2-type zinc finger DUF4187 PF13821.6 KER20144.1 - 0.034 13.9 0.3 14 5.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-C2HE PF16278.5 KER20144.1 - 0.62 10.5 5.9 9.1 6.8 0.1 3.9 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 KER20144.1 - 0.63 10.6 0.1 0.63 10.6 0.1 7.3 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-met PF12874.7 KER20144.1 - 0.79 10.2 23.5 3.4 8.2 0.4 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KER20144.1 - 1 9.7 22.1 0.14 12.5 0.3 4.8 4 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KER20144.1 - 3.9 7.3 21.0 0.98 9.2 0.5 5.7 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KER20144.1 - 6.3 7.2 23.7 0.8 10.1 0.1 5.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding BTB PF00651.31 KER20146.1 - 9e-06 25.9 1.2 0.22 11.8 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain FAD_binding_6 PF00970.24 KER20147.1 - 1.6e-12 47.6 0.0 1.5e-11 44.5 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KER20147.1 - 8.7e-11 41.8 0.0 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 KER20147.1 - 0.053 14.2 0.0 0.14 12.9 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Sel1 PF08238.12 KER20148.1 - 7.7e-05 23.2 0.0 0.43 11.3 0.0 3.7 4 0 0 4 4 4 2 Sel1 repeat HisK_N PF09385.10 KER20148.1 - 0.048 13.6 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase N terminal Tcp11 PF05794.13 KER20151.1 - 1.8e-96 324.0 0.0 2.2e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 RVT_1 PF00078.27 KER20151.1 - 2.9e-23 82.6 0.0 6.2e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_TS PF00889.19 KER20152.1 - 7.5e-36 123.7 0.8 1.2e-20 74.1 0.0 3.2 3 0 0 3 3 3 3 Elongation factor TS HBS1_N PF08938.10 KER20152.1 - 0.0019 18.4 0.0 3.4 8.0 0.0 2.3 2 0 0 2 2 2 2 HBS1 N-terminus UBA PF00627.31 KER20152.1 - 0.0021 17.9 0.2 3.3 7.7 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain CheR_N PF03705.15 KER20152.1 - 0.0041 16.8 0.3 3.9 7.3 0.0 2.5 2 0 0 2 2 2 2 CheR methyltransferase, all-alpha domain MbtH PF03621.13 KER20152.1 - 0.019 14.4 0.0 8.6 5.9 0.0 2.4 2 0 0 2 2 2 0 MbtH-like protein Acetyltransf_8 PF13523.6 KER20152.1 - 0.031 14.0 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Laminin_EGF PF00053.24 KER20154.1 - 5.8 7.1 13.9 1 9.6 2.9 2.8 1 1 1 2 2 2 0 Laminin EGF domain Plasmod_Pvs28 PF06247.11 KER20154.1 - 5.9 7.3 9.6 0.21 11.9 1.6 2.7 3 1 0 3 3 3 0 Pvs28 EGF domain TSP_1 PF00090.19 KER20155.1 - 0.0019 18.4 6.8 0.0042 17.3 6.8 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain TSP_1 PF00090.19 KER20156.1 - 0.0015 18.7 9.7 0.0015 18.7 9.7 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain EGF_3 PF12947.7 KER20156.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.3 2 0 0 2 2 2 0 EGF domain FXa_inhibition PF14670.6 KER20156.1 - 0.9 9.9 6.7 0.86 9.9 2.5 2.6 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site HSP20 PF00011.21 KER20157.1 - 4.6e-28 97.3 0.4 2.9e-14 53.0 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KER20157.1 - 4.9e-05 22.8 0.0 0.00084 18.9 0.0 2.4 2 1 0 2 2 2 1 HSP20-like domain found in ArsA MRP-S26 PF14943.6 KER20157.1 - 0.25 11.2 1.1 0.55 10.1 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 HHH_8 PF14716.6 KER20158.1 - 0.042 14.2 0.2 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Arginase PF00491.21 KER20158.1 - 0.14 11.6 0.1 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Arginase family Fic PF02661.18 KER20160.1 - 3.1e-24 85.7 0.0 8.8e-24 84.2 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family CEP44 PF15007.6 KER20160.1 - 1.2e-23 83.7 0.1 2.3e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 TPR_2 PF07719.17 KER20160.1 - 0.0065 16.5 0.7 0.053 13.6 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER20160.1 - 0.076 13.9 1.6 0.26 12.2 1.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER20160.1 - 0.13 12.0 0.2 0.31 10.8 0.2 1.6 1 0 0 1 1 1 0 TPR repeat DUF4172 PF13776.6 KER20160.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) zf-RING_UBOX PF13445.6 KER20161.1 - 1.6e-07 31.2 3.7 1.6e-07 31.2 3.7 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KER20161.1 - 3.3e-07 30.4 5.2 3.3e-06 27.2 5.3 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KER20161.1 - 3.9e-07 29.8 2.0 3.9e-07 29.8 2.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER20161.1 - 7.3e-06 25.9 3.4 7.3e-06 25.9 3.4 2.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KER20161.1 - 2.5e-05 24.0 3.5 2.5e-05 24.0 3.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER20161.1 - 0.00016 21.9 4.6 0.00016 21.9 4.6 2.6 2 1 0 2 2 2 1 Ring finger domain CK_II_beta PF01214.18 KER20161.1 - 0.013 15.3 0.5 0.023 14.5 0.5 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Prok-RING_4 PF14447.6 KER20161.1 - 0.083 12.8 12.2 0.16 11.8 7.5 3.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KER20161.1 - 0.92 9.8 6.2 0.56 10.5 2.8 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KER20161.1 - 1.8 8.4 10.1 0.062 13.1 3.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NAD_binding_1 PF00175.21 KER20163.1 - 3.6e-31 108.0 0.0 4.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KER20163.1 - 1.2e-05 25.4 0.0 0.0005 20.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KER20163.1 - 0.041 14.2 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pkinase PF00069.25 KER20165.1 - 3.6e-65 219.9 0.0 4.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20165.1 - 2.8e-32 112.0 0.0 3.7e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER20165.1 - 3.5e-05 22.9 0.2 0.00035 19.6 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KER20165.1 - 0.00091 18.9 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KER20165.1 - 0.0024 17.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KER20165.1 - 0.048 13.6 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER20165.1 - 0.081 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KER20165.1 - 0.085 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 KER20166.1 - 4.6e-57 190.0 1.4 5.5e-23 80.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhodanese PF00581.20 KER20167.1 - 5.9e-15 55.7 0.0 7.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain R3H PF01424.22 KER20168.1 - 0.00026 20.9 0.1 0.0014 18.6 0.0 2.2 2 1 1 3 3 3 1 R3H domain AAA_22 PF13401.6 KER20168.1 - 0.00078 19.7 0.0 0.0051 17.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KER20168.1 - 0.001 19.4 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KER20168.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 KER20168.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KER20168.1 - 0.019 14.8 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KER20168.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KER20168.1 - 0.08 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KER20168.1 - 0.085 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KER20168.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KER20168.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KER20168.1 - 0.15 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KER20168.1 - 0.19 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HA2 PF04408.23 KER20170.1 - 1e-17 64.3 0.0 2.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KER20170.1 - 8.7e-07 29.2 1.2 2.6e-06 27.7 0.0 2.4 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KER20170.1 - 3.8e-06 27.2 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_2 PF12796.7 KER20170.1 - 0.097 13.3 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KER20170.1 - 0.12 12.9 0.1 0.53 10.8 0.1 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 KER20170.1 - 0.16 12.6 0.1 0.96 10.2 0.1 2.5 1 0 0 1 1 1 0 Ankyrin repeat FKBP_C PF00254.28 KER20171.1 - 4.1e-12 46.3 0.0 6.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KER20171.1 - 2.8e-09 36.4 1.2 0.0005 19.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER20171.1 - 1.4e-05 24.9 5.2 0.34 11.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER20171.1 - 0.00019 21.9 0.3 0.00058 20.3 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER20171.1 - 0.00043 20.9 0.7 0.001 19.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KER20171.1 - 0.0006 19.5 0.2 0.0013 18.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 KER20171.1 - 0.00076 19.1 1.4 0.88 9.3 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KER20171.1 - 0.0012 18.9 1.3 1.2 9.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER20171.1 - 0.0035 18.0 0.1 0.83 10.6 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER20171.1 - 0.011 16.0 0.6 0.19 12.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER20171.1 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KER20171.1 - 0.049 14.3 0.7 6.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER20171.1 - 0.086 12.9 0.1 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat IBR PF01485.21 KER20172.1 - 3.7e-14 52.7 14.2 2.2e-09 37.4 2.3 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Toxin_16 PF07945.11 KER20172.1 - 5.6 6.9 14.4 0.17 11.8 3.4 3.6 3 0 0 3 3 3 0 Janus-atracotoxin V-SNARE_C PF12352.8 KER20174.1 - 3.4e-10 40.1 0.6 3.4e-10 40.1 0.6 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KER20174.1 - 0.0025 17.7 2.8 0.0025 17.7 0.1 2.5 3 0 0 3 3 3 1 Sec20 MSC PF09402.10 KER20174.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Metal_resist PF13801.6 KER20174.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Carn_acyltransf PF00755.20 KER20175.1 - 8e-148 493.7 0.0 1e-147 493.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_S8e PF01201.22 KER20176.1 - 5.2e-30 104.4 5.3 1.9e-29 102.6 5.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e V-ATPase_G PF03179.15 KER20178.1 - 3.2e-25 88.7 15.3 5.9e-25 87.8 15.3 1.5 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CENP-S PF15630.6 KER20178.1 - 6.4e-23 80.9 0.7 6.4e-23 80.9 0.7 1.8 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KER20178.1 - 3.4e-08 33.5 0.7 4.2e-07 30.0 0.1 2.4 1 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold RNA_pol_A_bac PF01000.26 KER20178.1 - 9e-05 22.8 0.4 0.00018 21.9 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Sds3 PF08598.11 KER20178.1 - 2.2 8.2 9.5 2.7 7.9 9.5 1.4 1 1 0 1 1 1 0 Sds3-like TCTP PF00838.17 KER20179.1 - 1.8e-54 184.5 1.3 2.1e-54 184.3 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein EMC3_TMCO1 PF01956.16 KER20179.1 - 0.14 11.9 0.4 0.21 11.3 0.4 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Dpy-30 PF05186.13 KER20182.1 - 5.2e-07 29.3 0.1 7.9e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif DUF1194 PF06707.11 KER20182.1 - 0.14 11.3 0.1 0.14 11.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1194) NYD-SP28_assoc PF14775.6 KER20184.1 - 0.0025 17.9 0.4 0.056 13.6 0.0 2.3 2 0 0 2 2 2 1 Sperm tail C-terminal domain STT3 PF02516.14 KER20185.1 - 3.7e-76 257.0 21.3 2.7e-73 247.6 17.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Pkinase PF00069.25 KER20187.1 - 3.8e-73 246.1 0.0 5.5e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20187.1 - 1.1e-41 142.8 0.0 2.2e-41 141.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KER20187.1 - 1.4e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER20187.1 - 0.0043 16.7 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KER20187.1 - 0.083 11.8 0.1 0.083 11.8 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KER20187.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KER20187.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 KER20187.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RVT_1 PF00078.27 KER20190.1 - 6.4e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBX PF00789.20 KER20190.1 - 3.1e-10 40.1 0.1 1.6e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KER20190.1 - 1.4e-06 28.0 0.2 3.4e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain GBP_PSP PF02425.15 KER20191.1 - 0.012 15.2 0.1 7 6.4 0.0 2.4 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Spc7_C2 PF15577.6 KER20193.1 - 0.073 13.2 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Spc7_C2 Tcp10_C PF07202.13 KER20196.1 - 0.018 15.0 0.4 0.028 14.4 0.4 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus SRP68 PF16969.5 KER20196.1 - 0.027 13.5 1.2 0.036 13.1 1.2 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 DUF2732 PF10809.8 KER20196.1 - 0.029 14.2 1.1 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) LnmK_N_HDF PF18238.1 KER20196.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain AdoMet_dc PF02675.15 KER20196.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase zf-C2H2_jaz PF12171.8 KER20200.1 - 0.0081 16.4 0.2 0.021 15.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER20200.1 - 0.0087 16.4 0.3 0.021 15.2 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER20200.1 - 0.35 11.8 2.9 0.88 10.6 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_C13 PF01650.18 KER20203.1 - 7.6e-105 350.0 14.2 1.3e-56 192.0 0.6 3.2 2 1 1 3 3 3 3 Peptidase C13 family Peptidase_C14 PF00656.22 KER20203.1 - 0.0001 22.3 0.1 0.064 13.2 0.0 2.3 2 0 0 2 2 2 2 Caspase domain Peptidase_C13 PF01650.18 KER20204.1 - 8.2e-24 84.5 0.9 8.1e-07 28.8 0.1 3.1 2 1 1 3 3 3 3 Peptidase C13 family Omp28 PF11551.8 KER20204.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein Omp28 Peptidase_C13 PF01650.18 KER20205.1 - 9e-29 100.8 6.5 7.2e-19 68.3 0.3 3.1 2 1 0 2 2 2 2 Peptidase C13 family Peptidase_C13 PF01650.18 KER20206.1 - 7.3e-49 166.6 0.3 1.2e-48 165.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20206.1 - 0.032 14.2 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Band_7 PF01145.25 KER20208.1 - 5.3e-24 85.2 2.3 1.3e-23 83.9 2.3 1.7 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.25 KER20209.1 - 6.3e-10 39.3 3.2 6.3e-10 39.3 3.2 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family RmlD_sub_bind PF04321.17 KER20210.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain SH3_10 PF17902.1 KER20210.1 - 0.14 12.2 1.4 0.41 10.7 1.4 1.7 1 1 0 1 1 1 0 SH3 domain Pkinase PF00069.25 KER20211.1 - 2.4e-42 145.1 0.0 4.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER20211.1 - 6.2e-14 51.9 0.0 3.4e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER20211.1 - 0.0038 16.1 0.0 0.0083 14.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Spc7_C2 PF15577.6 KER20211.1 - 0.12 12.5 0.1 0.53 10.4 0.1 2.1 1 0 0 1 1 1 0 Spc7_C2 Peptidase_S30 PF01577.16 KER20212.1 - 0.0011 18.7 0.1 0.0012 18.5 0.1 1.0 1 0 0 1 1 1 1 Potyvirus P1 protease FtsX PF02687.21 KER20213.1 - 0.078 13.4 0.4 0.078 13.4 0.4 2.1 2 0 0 2 2 2 0 FtsX-like permease family SLATT_1 PF18181.1 KER20213.1 - 1.4 8.9 4.6 2.7 7.9 4.3 1.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 BAR PF03114.18 KER20214.1 - 3.3e-22 79.3 3.8 4.1e-22 79.0 3.8 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KER20214.1 - 2.2e-05 23.8 3.0 3.3e-05 23.2 3.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD_SOX PF18371.1 KER20214.1 - 0.002 18.5 2.0 0.007 16.7 0.1 2.3 1 1 1 2 2 2 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase FapA PF03961.13 KER20214.1 - 0.017 13.7 0.9 0.02 13.5 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 KER20214.1 - 0.12 12.3 4.7 0.27 11.1 0.8 2.5 1 1 1 2 2 2 0 Prefoldin subunit MDH PF02315.16 KER20215.1 - 0.051 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Phosphorylase PF00343.20 KER20216.1 - 1.7e-303 1008.4 0.0 1.9e-303 1008.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TGF_beta PF00019.20 KER20219.1 - 7.8e-30 103.9 0.3 1.8e-29 102.8 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain RVT_1 PF00078.27 KER20220.1 - 1e-23 84.0 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1465 PF07323.12 KER20220.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) COG5 PF10392.9 KER20220.1 - 0.11 12.7 0.4 0.21 11.8 0.4 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RhoGAP PF00620.27 KER20223.1 - 5.4e-30 104.2 0.0 1.6e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain Y2_Tnp PF04986.13 KER20223.1 - 0.4 10.7 2.1 59 3.6 0.0 3.2 3 0 0 3 3 3 0 Putative transposase IZUMO PF15005.6 KER20223.1 - 2.9 8.4 5.8 2.3 8.7 0.5 2.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AAR2 PF05282.11 KER20224.1 - 1.9e-81 274.2 0.0 2.2e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein YjbH PF06082.11 KER20225.1 - 0.21 10.4 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Pkinase_Tyr PF07714.17 KER20226.1 - 2.9e-80 269.3 0.0 4.3e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER20226.1 - 9.7e-34 116.9 0.0 1.8e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain fn3 PF00041.21 KER20226.1 - 2.5e-07 31.0 0.2 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain Pkinase_fungal PF17667.1 KER20226.1 - 0.08 11.7 0.5 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Phage_lambda_P PF06992.11 KER20226.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Replication protein P CcmD PF04995.14 KER20226.1 - 0.36 10.9 11.5 0.52 10.4 2.2 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Oleosin PF01277.17 KER20226.1 - 3.8 7.3 5.8 15 5.3 0.3 2.3 1 1 1 2 2 2 0 Oleosin PDEase_I PF00233.19 KER20227.1 - 7.3e-81 271.4 5.5 1.3e-80 270.6 5.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KER20227.1 - 1.5e-13 51.5 1.4 2.8e-10 40.9 0.4 2.8 2 0 0 2 2 2 2 Phosphodiesterase 4 upstream conserved regions (UCR) DUF3504 PF12012.8 KER20230.1 - 8e-69 230.7 0.0 4.8e-40 137.1 0.0 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF3504) TFIIF_beta_N PF17683.1 KER20231.1 - 0.11 13.1 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Pneumo_M2 PF07380.11 KER20232.1 - 0.12 12.7 0.4 0.15 12.3 0.4 1.2 1 0 0 1 1 1 0 Pneumovirus M2 protein SmpA_OmlA PF04355.13 KER20234.1 - 0.012 15.4 0.0 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 SmpA / OmlA family Cnn_1N PF07989.11 KER20234.1 - 0.032 14.4 0.0 10 6.4 0.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Rab_bind PF16704.5 KER20234.1 - 0.038 14.0 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Rab binding domain TPR_10 PF13374.6 KER20236.1 - 1.9e-29 100.7 12.3 4.8e-13 48.5 0.2 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KER20236.1 - 1.5e-25 89.3 5.3 5.7e-11 42.6 1.3 4.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KER20236.1 - 6.7e-13 47.7 2.4 0.0032 17.4 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER20236.1 - 1.5e-12 46.8 8.0 0.00026 20.7 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER20236.1 - 2.5e-10 39.6 7.6 0.0018 18.2 0.5 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KER20236.1 - 5.9e-09 35.7 6.1 0.085 13.5 0.9 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KER20236.1 - 3.2e-08 33.4 0.7 1.1e-07 31.5 0.2 2.1 2 1 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 KER20236.1 - 2.1e-07 30.6 4.1 0.16 12.3 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER20236.1 - 1.6e-06 28.4 7.8 0.029 15.2 0.5 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER20236.1 - 2.5e-05 24.8 7.2 0.13 12.9 0.9 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER20236.1 - 9.1e-05 22.9 10.7 0.057 13.9 0.0 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER20236.1 - 0.013 15.2 1.4 0.49 10.1 0.2 3.2 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 KER20236.1 - 0.014 15.8 5.1 3.8 8.1 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KER20236.1 - 0.11 12.5 0.6 5.8 7.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER20236.1 - 0.11 13.2 0.4 0.11 13.2 0.4 4.1 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER20236.1 - 0.13 12.5 2.3 0.92 9.8 0.3 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 KER20236.1 - 0.17 12.1 2.4 1.9 8.8 0.1 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_20 PF14561.6 KER20236.1 - 0.19 12.1 0.9 1.8 9.0 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Na_K-ATPase PF00287.18 KER20238.1 - 1.1e-23 83.8 5.4 7.3e-23 81.1 5.4 1.9 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain DUF1330 PF07045.11 KER20239.1 - 0.00012 22.3 0.0 0.54 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) KapB PF08810.10 KER20239.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase associated protein B Glyco_hydro_38N PF01074.22 KER20240.1 - 1.2e-84 284.1 1.6 1.5e-84 283.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KER20240.1 - 7.1e-24 83.8 0.1 2.2e-23 82.2 0.1 1.8 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 KER20240.1 - 2.3e-21 76.9 0.0 3.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain HMG_box PF00505.19 KER20241.1 - 7.8e-26 90.3 3.8 1.3e-25 89.6 3.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER20241.1 - 5.6e-11 42.9 1.4 1e-10 42.0 1.4 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 KER20242.1 - 2e-25 89.0 3.8 3.5e-25 88.2 3.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER20242.1 - 2e-10 41.1 2.9 2.8e-10 40.6 1.4 2.0 2 0 0 2 2 2 1 HMG-box domain Peptidase_M3 PF01432.20 KER20243.1 - 8.5e-35 120.9 0.0 2.7e-18 66.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M3 Snf7 PF03357.21 KER20244.1 - 1.2e-12 47.8 4.9 1.8e-12 47.2 4.9 1.2 1 0 0 1 1 1 1 Snf7 Rep_fac-A_C PF08646.10 KER20244.1 - 0.46 10.2 2.8 10 5.8 0.1 2.2 1 1 0 2 2 2 0 Replication factor-A C terminal domain EF-hand_1 PF00036.32 KER20245.1 - 1.9e-34 114.6 11.6 7.6e-06 25.1 0.1 6.3 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 KER20245.1 - 1.8e-31 105.3 11.3 1.8e-05 24.3 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 KER20245.1 - 1.6e-27 95.7 12.8 5.2e-09 36.4 1.5 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KER20245.1 - 1.5e-20 71.6 19.1 0.00022 20.6 0.3 6.4 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 KER20245.1 - 2.7e-11 43.1 13.4 0.0035 17.2 0.1 6.4 6 1 1 7 7 7 4 EF-hand domain pair EF-hand_10 PF14788.6 KER20245.1 - 9.3e-07 28.6 6.7 0.056 13.3 0.1 4.4 3 1 1 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KER20245.1 - 0.00044 20.5 3.0 12 6.3 0.1 5.3 3 1 1 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KER20245.1 - 0.001 19.2 2.0 1.4 9.2 0.0 3.8 4 1 1 5 5 5 2 Dockerin type I domain GPHH PF16905.5 KER20245.1 - 0.0075 16.0 0.0 1.1 9.1 0.0 3.1 4 0 0 4 4 4 1 Voltage-dependent L-type calcium channel, IQ-associated Caleosin PF05042.13 KER20245.1 - 0.03 14.2 0.9 36 4.2 0.1 4.2 4 1 0 4 4 4 0 Caleosin related protein Toprim_2 PF13155.6 KER20245.1 - 0.063 13.7 0.2 5 7.6 0.0 3.5 1 1 3 4 4 4 0 Toprim-like WWE PF02825.20 KER20245.1 - 0.14 12.7 0.0 7.5 7.2 0.0 2.6 2 0 0 2 2 2 0 WWE domain Glyco_transf_22 PF03901.17 KER20246.1 - 1.4e-61 209.0 38.2 2e-61 208.5 38.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Mago_nashi PF02792.14 KER20247.1 - 1.2e-48 164.8 0.0 1.4e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Mago nashi protein CARD PF00619.21 KER20247.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Caspase recruitment domain Ras PF00071.22 KER20248.1 - 8.6e-31 106.7 1.3 3.5e-30 104.7 1.3 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER20248.1 - 3.4e-24 85.4 0.2 5.2e-23 81.5 0.2 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER20248.1 - 9.4e-10 38.2 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER20248.1 - 2.6e-06 27.0 0.2 3.6e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KER20248.1 - 0.0026 17.3 0.0 0.007 15.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KER20248.1 - 0.014 15.4 0.3 0.032 14.3 0.2 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MDD_C PF18376.1 KER20250.1 - 2.1e-48 164.5 0.3 1.4e-35 122.8 0.0 2.3 2 0 0 2 2 2 2 Mevalonate 5-diphosphate decarboxylase C-terminal domain DUF758 PF05527.11 KER20251.1 - 2.4e-41 141.7 0.0 2.7e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Imm75 PF15660.6 KER20251.1 - 0.097 12.9 0.1 0.41 10.9 0.1 2.0 1 1 0 1 1 1 0 Putative Immunity protein 75 Gar1 PF04410.14 KER20254.1 - 6.7e-24 84.4 0.0 9e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ldl_recept_a PF00057.18 KER20256.1 - 8.7e-05 22.7 0.9 8.7e-05 22.7 0.9 2.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A PRA1 PF03208.19 KER20256.1 - 0.068 12.8 1.3 0.21 11.2 1.3 1.8 1 0 0 1 1 1 0 PRA1 family protein PRKCSH-like PF12999.7 KER20256.1 - 0.71 9.6 2.5 25 4.6 0.8 2.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like vATP-synt_AC39 PF01992.16 KER20257.1 - 2.5e-115 385.6 0.5 2.8e-115 385.4 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CDV3 PF15359.6 KER20258.1 - 0.24 11.9 7.8 0.05 14.1 3.8 1.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF1041 PF06292.17 KER20260.1 - 1.2e-24 86.7 0.6 3.7e-24 85.1 0.6 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) RVT_1 PF00078.27 KER20260.1 - 7.9e-08 32.1 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C2 PF00168.30 KER20260.1 - 0.00098 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.29 KER20260.1 - 0.0055 17.2 0.1 0.052 14.1 0.0 2.6 2 1 0 2 2 2 1 PH domain DUF4426 PF14467.6 KER20260.1 - 0.084 12.8 0.0 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) zf-C2H2 PF00096.26 KER20262.1 - 5.9e-07 29.6 27.1 0.0014 19.0 2.0 4.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER20262.1 - 0.00095 19.8 26.0 0.07 14.0 1.7 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER20262.1 - 0.0019 18.5 0.6 0.0019 18.5 0.6 5.1 5 1 0 5 5 5 1 Zinc-finger double domain Mut7-C PF01927.16 KER20262.1 - 0.011 15.9 4.8 0.011 15.9 4.8 2.6 2 1 0 3 3 3 0 Mut7-C RNAse domain zf-C2H2_3rep PF18868.1 KER20262.1 - 0.057 14.1 6.3 0.48 11.1 1.4 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KER20262.1 - 0.08 12.6 0.2 0.08 12.6 0.2 2.8 3 1 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 KER20262.1 - 0.45 10.1 6.9 3.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KER20262.1 - 1.6 9.1 10.0 0.39 11.0 5.7 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KER20262.1 - 1.7 8.8 10.6 19 5.5 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain Kinesin PF00225.23 KER20263.1 - 9.1e-87 291.1 0.0 2.1e-86 289.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER20263.1 - 7.5e-13 48.7 0.0 7.5e-13 48.7 0.0 3.8 5 0 0 5 5 5 1 Microtubule binding SlyX PF04102.12 KER20263.1 - 0.014 16.0 5.4 0.014 16.0 5.4 5.0 4 1 1 5 5 5 0 SlyX DUF3480 PF11979.8 KER20263.1 - 0.27 10.2 2.2 0.52 9.2 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) 2_5_RNA_ligase2 PF13563.6 KER20263.1 - 0.39 10.6 4.9 1.5 8.7 0.2 3.8 3 1 1 4 4 4 0 2'-5' RNA ligase superfamily bZIP_1 PF00170.21 KER20263.1 - 4.2 7.5 16.9 3 8.0 0.9 3.5 3 0 0 3 3 3 0 bZIP transcription factor DUF812 PF05667.11 KER20263.1 - 7.4 5.3 33.3 1 8.1 10.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Kunitz_BPTI PF00014.23 KER20265.1 - 2.6e-20 72.4 5.3 3.9e-20 71.8 5.3 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 KER20266.1 - 1.5e-07 31.5 8.4 2.3e-07 30.9 8.4 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain RhoGEF PF00621.20 KER20268.1 - 2.2e-35 122.5 5.1 5.1e-35 121.4 5.1 1.6 1 1 0 1 1 1 1 RhoGEF domain IQ PF00612.27 KER20268.1 - 0.011 15.4 2.6 0.032 14.0 2.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif RasGEF_N PF00618.20 KER20271.1 - 3.1e-13 49.9 0.1 7.1e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 KER20271.1 - 0.031 14.8 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 PH domain RasGEF PF00617.19 KER20272.1 - 2.3e-55 187.6 2.1 3.7e-55 186.9 2.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KER20272.1 - 0.0004 20.6 0.3 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SurA_N PF09312.11 KER20272.1 - 0.6 10.2 4.8 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 SurA N-terminal domain Gemini_BL1 PF00845.19 KER20273.1 - 0.03 13.9 1.5 0.044 13.4 1.5 1.1 1 0 0 1 1 1 0 Geminivirus BL1 movement protein Trp_Tyr_perm PF03222.13 KER20275.1 - 0.18 10.8 0.0 0.18 10.8 0.0 1.0 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Porin_3 PF01459.22 KER20276.1 - 9.5e-40 136.8 0.4 1.2e-39 136.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Acetyltransf_16 PF05301.11 KER20278.1 - 7.7e-58 195.1 0.0 1.2e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 KER20278.1 - 0.00047 20.4 0.0 0.00076 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KER20278.1 - 0.0038 17.6 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KER20278.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PH PF00169.29 KER20280.1 - 2.2e-06 28.1 0.0 4.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH PF00169.29 KER20281.1 - 2.4e-05 24.8 0.1 6.9e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 PH domain DUF4200 PF13863.6 KER20281.1 - 6.4e-05 23.3 8.3 0.015 15.7 3.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) Myosin_tail_1 PF01576.19 KER20281.1 - 0.00013 20.0 2.6 0.00015 19.8 2.6 1.0 1 0 0 1 1 1 1 Myosin tail DUF5132 PF17195.4 KER20281.1 - 0.0023 18.0 0.9 2 8.6 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF5132) CortBP2 PF09727.9 KER20281.1 - 0.0028 17.6 10.2 0.0066 16.4 10.2 1.5 1 1 0 1 1 1 1 Cortactin-binding protein-2 Methyltransf_14 PF08484.11 KER20281.1 - 0.0053 16.6 1.8 0.87 9.4 1.9 2.1 1 1 1 2 2 2 1 C-methyltransferase C-terminal domain BLOC1_2 PF10046.9 KER20281.1 - 0.021 15.1 3.0 0.049 13.9 3.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TolA_bind_tri PF16331.5 KER20281.1 - 0.028 14.5 2.2 8.3 6.6 1.9 2.9 1 1 1 2 2 2 0 TolA binding protein trimerisation LPP PF04728.13 KER20281.1 - 0.032 14.6 0.4 9.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FapA PF03961.13 KER20281.1 - 0.034 12.8 1.0 0.041 12.5 1.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rop-like PF05082.13 KER20281.1 - 0.044 13.6 4.1 4.1 7.3 0.3 2.5 2 0 0 2 2 2 0 Rop-like JIP_LZII PF16471.5 KER20281.1 - 0.059 13.6 3.6 3.9 7.7 2.1 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF5595 PF18077.1 KER20281.1 - 0.06 13.4 4.6 3.4 7.8 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) DUF1192 PF06698.11 KER20281.1 - 0.069 13.2 1.7 11 6.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlxA PF14282.6 KER20281.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 FlxA-like protein PH_13 PF16652.5 KER20281.1 - 0.1 12.4 1.5 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 Pleckstrin homology domain AAA_23 PF13476.6 KER20281.1 - 0.11 13.0 2.8 0.13 12.8 2.8 1.1 1 0 0 1 1 1 0 AAA domain DUF848 PF05852.11 KER20281.1 - 0.13 12.4 5.9 0.91 9.6 5.1 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1843 PF08898.10 KER20281.1 - 0.15 12.6 3.9 8.2 7.0 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) CSN5_C PF18323.1 KER20281.1 - 0.23 12.4 2.0 11 7.1 1.1 2.5 1 1 2 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain CAMP_factor PF07373.11 KER20281.1 - 0.25 10.9 3.4 3.3 7.3 1.0 2.0 1 1 1 2 2 2 0 CAMP factor (Cfa) COG5 PF10392.9 KER20281.1 - 0.35 11.1 3.8 2.4 8.3 1.5 2.2 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DivIC PF04977.15 KER20281.1 - 0.42 10.4 11.3 2.5 8.0 1.2 3.4 1 1 2 3 3 3 0 Septum formation initiator FRQ PF09421.10 KER20281.1 - 0.46 8.5 2.6 3.6 5.5 0.3 2.0 1 1 1 2 2 2 0 Frequency clock protein Shugoshin_N PF07558.11 KER20281.1 - 1.1 9.2 6.3 4.6 7.2 0.4 2.6 3 0 0 3 3 2 0 Shugoshin N-terminal coiled-coil region Suppressor_APC PF11414.8 KER20281.1 - 1.2 9.3 11.5 1.7 8.8 0.7 2.4 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein BST2 PF16716.5 KER20281.1 - 5.8 7.6 10.0 8.1 7.1 1.7 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 RSN1_TM PF13967.6 KER20283.1 - 8.3e-18 64.6 0.4 1.5e-17 63.8 0.4 1.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF2208 PF09973.9 KER20283.1 - 0.36 10.4 1.7 7.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RSN1_7TM PF02714.15 KER20284.1 - 3.8e-24 85.4 18.5 2.9e-20 72.7 1.8 3.2 3 0 0 3 3 3 3 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KER20284.1 - 9e-17 61.8 0.0 1.4e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter UCH PF00443.29 KER20285.1 - 1.2e-09 38.1 0.2 1.1e-05 25.1 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER20285.1 - 0.0074 15.9 1.6 0.01 15.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RVT_1 PF00078.27 KER20286.1 - 2.8e-11 43.4 0.0 7.5e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.29 KER20286.1 - 0.0025 17.4 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Goodbye PF17109.5 KER20288.1 - 0.023 15.2 0.1 0.043 14.3 0.0 1.4 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Filament PF00038.21 KER20288.1 - 0.035 13.7 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein Myosin_tail_1 PF01576.19 KER20288.1 - 0.055 11.3 0.4 0.069 10.9 0.4 1.0 1 0 0 1 1 1 0 Myosin tail RVT_1 PF00078.27 KER20289.1 - 4e-24 85.4 0.0 1.1e-23 84.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 KER20289.1 - 0.0017 18.6 1.7 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 GIY-YIG catalytic domain PWI PF01480.17 KER20290.1 - 5.6e-29 100.3 0.1 1.3e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 PWI domain ParG PF09274.10 KER20290.1 - 0.17 12.1 0.5 4.2 7.6 0.1 2.3 2 0 0 2 2 2 0 ParG zf-LITAF-like PF10601.9 KER20291.1 - 6.5e-20 71.2 10.7 7.6e-20 71.0 10.7 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF4428 PF14471.6 KER20291.1 - 0.00014 21.7 1.9 0.087 12.8 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-Di19 PF05605.12 KER20291.1 - 0.0038 17.5 1.9 1.1 9.6 0.1 2.2 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF5318 PF17249.2 KER20291.1 - 0.021 14.6 0.6 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5318) zf-UDP PF14569.6 KER20291.1 - 2.4 8.3 6.9 16 5.7 6.9 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger RPEL PF02755.15 KER20292.1 - 3.5e-12 45.6 14.9 0.00015 21.3 5.3 4.4 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.27 KER20292.1 - 0.00022 20.9 0.2 0.00062 19.5 0.2 1.7 1 0 0 1 1 1 1 SAP domain RVT_1 PF00078.27 KER20294.1 - 1.3e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rib PF08428.10 KER20294.1 - 0.05 13.6 0.6 1.9 8.5 0.2 2.3 2 0 0 2 2 2 0 Rib/alpha-like repeat DUF2340 PF10209.9 KER20297.1 - 2.9e-28 98.7 0.0 3.3e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Aa_trans PF01490.18 KER20298.1 - 2.2e-27 95.8 11.5 3e-27 95.4 11.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Exo_endo_phos PF03372.23 KER20298.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER20298.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4122 PF13498.6 KER20298.1 - 0.2 11.3 0.1 0.33 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) UCH PF00443.29 KER20299.1 - 5.1e-37 127.8 0.0 7.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KER20299.1 - 4.6e-21 74.3 0.0 5.9e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KER20299.1 - 1.6e-12 47.6 0.0 1.2e-07 31.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_3 PF09288.10 KER20299.1 - 0.018 14.8 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_4 PF14555.6 KER20299.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.31 KER20300.1 - 1.8e-21 75.7 0.0 3.5e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH PF00443.29 KER20300.1 - 2.3e-13 50.3 0.0 2.9e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER20300.1 - 4.3e-08 33.1 0.0 1.3e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_3 PF09288.10 KER20300.1 - 0.0079 16.0 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UBA_4 PF14555.6 KER20300.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain CBFD_NFYB_HMF PF00808.23 KER20301.1 - 8.9e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER20301.1 - 0.0011 19.3 0.6 0.003 17.9 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KER20301.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF572 PF04502.13 KER20301.1 - 0.008 15.8 0.4 0.01 15.5 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TAF PF02969.17 KER20301.1 - 0.096 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) EBP50_C PF09007.11 KER20301.1 - 0.12 13.4 0.3 0.12 13.4 0.3 1.5 2 0 0 2 2 2 0 EBP50, C-terminal DUF4719 PF15843.5 KER20301.1 - 0.17 12.0 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) CBFD_NFYB_HMF PF00808.23 KER20302.1 - 1.8e-13 50.5 0.0 2.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER20302.1 - 0.00088 19.6 0.5 0.007 16.7 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KER20302.1 - 0.0032 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.17 KER20302.1 - 0.12 12.5 0.4 0.31 11.2 0.2 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) vATP-synt_E PF01991.18 KER20303.1 - 2.6e-26 92.3 0.0 3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SRCR PF00530.18 KER20305.1 - 3.7e-27 94.7 5.0 3.5e-14 53.1 1.4 2.8 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 KER20305.1 - 4.2e-26 92.3 0.1 6.1e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 KER20305.1 - 4.2e-07 30.4 0.1 0.011 16.2 0.1 2.7 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KER20305.1 - 0.011 16.2 0.1 0.35 11.4 0.1 2.4 2 0 0 2 2 2 0 Hepsin, SRCR domain Jnk-SapK_ap_N PF09744.9 KER20306.1 - 9.6e-45 152.6 33.4 1.2e-44 152.3 14.6 3.1 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KER20306.1 - 4.9e-22 77.9 2.5 4.9e-22 77.9 2.5 4.2 3 2 1 5 5 5 1 JNK-interacting protein leucine zipper II Spc7 PF08317.11 KER20306.1 - 0.00025 20.0 6.9 0.00025 20.0 6.9 2.5 2 1 0 2 2 2 2 Spc7 kinetochore protein RILP PF11461.8 KER20306.1 - 0.0097 16.1 0.5 0.0097 16.1 0.5 2.3 2 0 0 2 2 2 1 Rab interacting lysosomal protein CCDC92 PF14916.6 KER20306.1 - 0.06 13.1 6.3 2.2 8.1 0.0 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function DUF4407 PF14362.6 KER20306.1 - 0.07 12.5 10.7 0.44 9.9 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KER20306.1 - 0.81 9.1 30.4 1.8 8.0 13.4 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Ly49 PF08391.10 KER20306.1 - 0.9 9.9 10.6 0.17 12.2 0.8 2.5 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TSC22 PF01166.18 KER20306.1 - 1.6 9.1 14.9 7.3 7.0 0.2 4.7 4 1 0 4 4 4 0 TSC-22/dip/bun family DUF745 PF05335.13 KER20306.1 - 2.6 7.7 13.5 0.027 14.2 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) EzrA PF06160.12 KER20306.1 - 2.9 5.9 23.9 0.45 8.6 5.0 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KER20306.1 - 4.6 6.7 16.7 6.1 6.3 4.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4287 PF14117.6 KER20310.1 - 0.084 13.0 0.1 0.67 10.1 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4287) Asp PF00026.23 KER20311.1 - 6.2e-25 88.3 0.0 7.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER20311.1 - 1.5e-07 31.3 0.1 5.4e-07 29.5 0.0 1.9 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal VPS13 PF16908.5 KER20312.1 - 6.1e-18 65.5 0.6 2.5e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 KER20313.1 - 1.6e-33 116.2 0.0 7.2e-33 114.1 0.0 2.2 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 KER20313.1 - 3.5e-24 85.5 6.7 4.2e-18 65.7 0.6 3.4 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 KER20313.1 - 6.9e-07 28.9 0.0 0.015 14.7 0.0 3.8 4 0 0 4 4 4 2 Repeating coiled region of VPS13 Il13Ra_Ig PF18001.1 KER20313.1 - 0.06 13.4 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain ATG_C PF09333.11 KER20313.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain zf-UBP_var PF17807.1 KER20315.1 - 2.2e-17 62.6 0.0 4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger ig PF00047.25 KER20315.1 - 0.00065 19.8 0.1 2 8.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain RasGAP PF00616.19 KER20317.1 - 1.6e-22 80.2 0.0 2.7e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CFEM PF05730.11 KER20318.1 - 0.0083 16.2 1.2 0.02 15.0 1.2 1.7 1 0 0 1 1 1 1 CFEM domain VirC2 PF07181.11 KER20319.1 - 0.13 11.7 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 VirC2 protein zf-C4 PF00105.18 KER20321.1 - 3.4e-42 142.7 24.7 2.6e-27 95.1 7.2 2.8 2 1 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER20321.1 - 2.5e-08 33.8 0.1 4.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.16 KER20321.1 - 0.002 18.4 0.5 0.002 18.4 0.5 3.2 3 0 0 3 3 3 2 C1 domain zf-RRPl_C4 PF17026.5 KER20321.1 - 1.5 9.0 6.0 5.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Laminin_N PF00055.17 KER20325.1 - 6.5e-76 255.0 0.6 6.5e-76 255.0 0.6 2.9 4 0 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KER20325.1 - 2.6e-68 226.0 208.8 2.4e-11 43.6 12.6 11.3 10 1 1 11 11 11 10 Laminin EGF domain Laminin_I PF06008.14 KER20325.1 - 0.0012 18.6 9.9 0.0012 18.6 9.9 4.3 2 1 1 3 3 3 1 Laminin Domain I Nup54 PF13874.6 KER20325.1 - 0.0043 17.2 5.4 0.0043 17.2 5.4 6.5 3 2 3 7 7 7 2 Nucleoporin complex subunit 54 F5_F8_type_C PF00754.25 KER20325.1 - 0.15 12.2 0.2 0.39 10.9 0.2 1.6 1 0 0 1 1 1 0 F5/8 type C domain T2SSF PF00482.23 KER20325.1 - 0.93 9.5 4.5 1.5 8.8 0.4 2.9 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Prominin PF05478.11 KER20325.1 - 2.4 6.0 40.1 0.98 7.3 20.8 2.6 1 1 1 2 2 2 0 Prominin DUF3584 PF12128.8 KER20325.1 - 8.3 3.8 59.8 0.081 10.4 36.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPH PF13868.6 KER20327.1 - 5.4e-65 219.2 138.5 5.4e-65 219.2 138.5 2.4 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain V-ATPase_C PF03223.15 KER20328.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 V-ATPase subunit C FERM_N PF09379.10 KER20330.1 - 4.7e-11 42.5 0.0 1.4e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KER20330.1 - 2.4e-10 40.8 0.1 3e-08 34.1 0.0 3.4 2 1 0 2 2 2 1 FERM central domain FERM_C PF09380.10 KER20330.1 - 3.2e-09 37.0 0.1 6.5e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain HLH PF00010.26 KER20331.1 - 1.5e-13 50.5 1.1 3.4e-13 49.3 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 KER20331.1 - 1.1e-09 38.4 1.0 3.3e-09 36.8 1.0 1.9 1 0 0 1 1 1 1 Hairy Orange DUF4542 PF15075.6 KER20331.1 - 0.028 14.8 0.6 0.079 13.4 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) Dynein_light PF01221.18 KER20332.1 - 3.4e-24 85.0 0.0 3.8e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Cyt-b5 PF00173.28 KER20333.1 - 3e-21 75.4 0.0 5.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KER20333.1 - 3.8e-21 76.1 20.7 3.8e-21 76.1 20.7 1.8 1 1 1 2 2 2 1 Fatty acid desaturase DUF3270 PF11674.8 KER20333.1 - 0.055 13.6 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Pkinase PF00069.25 KER20334.1 - 4.3e-64 216.4 0.0 7e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20334.1 - 2e-27 96.1 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HYLS1_C PF15311.6 KER20334.1 - 8.1e-10 39.3 0.1 8.1e-10 39.3 0.1 4.0 4 1 0 4 4 4 1 Hydrolethalus syndrome protein 1 C-terminus Kinase-like PF14531.6 KER20334.1 - 5.6e-05 22.6 0.2 0.00041 19.8 0.2 2.0 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER20334.1 - 0.0073 15.9 0.2 0.017 14.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family MBD_C PF14048.6 KER20334.1 - 0.1 13.3 0.1 0.42 11.4 0.1 2.1 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 gag-asp_proteas PF13975.6 KER20335.1 - 4.3e-06 27.2 0.0 8.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER20335.1 - 8.2e-06 26.4 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER20335.1 - 0.029 14.7 0.0 0.058 13.7 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Cofilin_ADF PF00241.20 KER20336.1 - 6.5e-36 122.8 0.2 7.8e-36 122.5 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 KER20338.1 - 2.9e-30 104.6 0.1 3.2e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2004 PF09406.10 KER20338.1 - 0.04 14.2 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) GoLoco PF02188.17 KER20339.1 - 1.9e-31 107.1 36.0 1.6e-08 33.9 0.2 4.8 5 0 0 5 5 5 4 GoLoco motif TPR_12 PF13424.6 KER20339.1 - 1.5e-29 102.1 24.2 2.1e-09 37.5 0.9 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KER20339.1 - 5.2e-25 86.2 18.5 8.7e-05 22.2 0.9 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KER20339.1 - 4.2e-19 67.1 19.7 0.00024 20.9 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KER20339.1 - 2.8e-17 61.4 11.1 0.00021 21.3 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KER20339.1 - 7.9e-13 47.5 22.8 0.013 15.6 0.7 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KER20339.1 - 8.9e-07 28.6 24.1 0.15 11.9 0.1 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat Rapsyn_N PF10579.9 KER20339.1 - 4.6e-06 26.6 0.1 0.079 13.1 0.0 2.9 2 1 0 2 2 2 2 Rapsyn N-terminal myristoylation and linker region TPR_MalT PF17874.1 KER20339.1 - 4.9e-05 22.9 3.7 0.026 13.9 0.1 2.4 2 0 0 2 2 2 2 MalT-like TPR region SNAP PF14938.6 KER20339.1 - 0.00045 19.7 0.2 0.00045 19.7 0.2 2.3 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 KER20339.1 - 0.0037 16.9 11.2 2 8.1 0.2 6.1 4 2 1 5 5 5 1 TPR repeat TPR_14 PF13428.6 KER20339.1 - 0.0072 17.1 9.5 0.4 11.6 0.1 6.0 6 2 2 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER20339.1 - 0.012 16.0 5.6 1.7 9.2 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat CHASE3 PF05227.13 KER20339.1 - 0.031 14.2 0.5 0.031 14.2 0.5 2.5 2 0 0 2 2 2 0 CHASE3 domain ANAPC5 PF12862.7 KER20339.1 - 0.17 12.0 1.4 21 5.3 0.0 3.3 3 2 0 3 3 2 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 KER20339.1 - 0.21 12.1 7.8 20 5.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Paf67 PF10255.9 KER20339.1 - 0.9 8.5 3.4 10 5.0 0.0 2.4 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 TPR_16 PF13432.6 KER20339.1 - 4.4 8.0 14.3 5.8 7.6 1.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KER20344.1 - 0.0088 16.5 0.3 0.019 15.4 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER20344.1 - 0.14 13.1 0.5 0.36 11.8 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PKD_channel PF08016.12 KER20346.1 - 7.8e-132 439.9 13.1 1e-131 439.6 13.1 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KER20346.1 - 8.1e-24 84.2 29.1 1.3e-23 83.5 29.1 1.3 1 0 0 1 1 1 1 Ion transport protein EF-hand_7 PF13499.6 KER20346.1 - 0.0048 17.3 1.8 0.026 15.0 0.4 2.7 1 1 1 2 2 2 2 EF-hand domain pair THOC7 PF05615.13 KER20346.1 - 0.01 16.1 0.2 0.01 16.1 0.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 EF-hand_8 PF13833.6 KER20346.1 - 0.011 15.6 1.8 0.033 14.0 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KER20346.1 - 0.1 12.2 0.9 4.6 7.0 0.4 3.2 3 0 0 3 3 3 0 EF hand DUF1599 PF07659.11 KER20346.1 - 0.12 12.9 0.4 1.4 9.5 0.2 2.9 3 0 0 3 3 3 0 Nucleotide modification associated domain 1 ADIP PF11559.8 KER20346.1 - 0.57 10.3 5.7 6.3 6.9 0.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF371 PF04027.13 KER20347.1 - 0.047 13.6 0.0 2 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF371) TetR_C_30 PF17939.1 KER20347.1 - 0.2 11.9 0.0 11 6.3 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mito_carr PF00153.27 KER20348.1 - 5.3e-50 167.3 2.8 3.1e-17 62.3 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 KER20349.1 - 7.6e-06 26.6 1.4 7.6e-06 26.6 1.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SKG6 PF08693.10 KER20349.1 - 0.044 13.2 2.7 0.11 11.9 2.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1561 PF07598.11 KER20349.1 - 0.054 11.7 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Podoplanin PF05808.11 KER20349.1 - 0.76 9.9 3.5 1.3 9.1 3.5 1.3 1 0 0 1 1 1 0 Podoplanin TTC5_OB PF16669.5 KER20350.1 - 4.5e-37 126.3 0.0 8.9e-37 125.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain Kinesin PF00225.23 KER20350.1 - 5.4e-20 71.6 0.1 3.1e-19 69.1 0.0 2.3 2 1 1 3 3 3 1 Kinesin motor domain TPR_2 PF07719.17 KER20350.1 - 3.2e-09 36.2 0.0 9.8e-06 25.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KER20350.1 - 1.4e-08 34.3 0.0 0.00048 19.8 0.0 3.6 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 KER20350.1 - 6.7e-08 32.0 0.0 0.00018 21.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER20350.1 - 4.2e-06 26.8 0.2 0.36 11.3 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER20350.1 - 9.4e-06 25.5 0.0 0.00049 20.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER20350.1 - 0.00014 22.5 4.4 0.046 14.4 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER20350.1 - 0.00037 20.7 0.3 0.0025 18.1 0.0 2.7 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER20350.1 - 0.00052 20.6 0.0 0.00052 20.6 0.0 5.0 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER20350.1 - 0.00074 20.0 5.4 0.63 10.6 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat DivIVA PF05103.13 KER20350.1 - 0.0074 16.4 10.0 0.0074 16.4 10.0 3.4 3 0 0 3 3 3 1 DivIVA protein Microtub_bd PF16796.5 KER20350.1 - 0.0095 15.9 0.0 0.046 13.6 0.1 2.2 2 0 0 2 2 2 1 Microtubule binding Flot PF15975.5 KER20350.1 - 0.23 11.7 2.8 0.58 10.4 2.8 1.7 1 0 0 1 1 1 0 Flotillin Spc7 PF08317.11 KER20350.1 - 1.5 7.6 17.4 4 6.2 17.4 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KER20350.1 - 5.3 7.3 5.2 2.3 8.5 1.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA TnpV PF14198.6 KER20350.1 - 8.5 6.4 12.3 6 6.9 2.3 2.7 1 1 1 2 2 2 0 Transposon-encoded protein TnpV CEP63 PF17045.5 KER20351.1 - 0.046 13.6 1.9 5.7 6.8 0.1 2.8 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Penaeidin PF05927.11 KER20353.1 - 0.12 13.2 2.6 18 6.2 0.2 2.6 2 0 0 2 2 2 0 Penaeidin PAM2 PF07145.15 KER20353.1 - 0.14 11.9 0.6 0.59 9.9 0.6 2.2 1 0 0 1 1 1 0 Ataxin-2 C-terminal region SBP_bac_1 PF01547.25 KER20353.1 - 0.17 11.8 0.6 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein FlxA PF14282.6 KER20353.1 - 0.19 11.7 10.3 0.52 10.3 10.3 1.6 1 0 0 1 1 1 0 FlxA-like protein UBA PF00627.31 KER20353.1 - 0.26 11.2 0.6 0.52 10.3 0.0 1.7 2 0 0 2 2 2 0 UBA/TS-N domain DUF1856 PF08983.10 KER20353.1 - 5.3 7.4 8.4 2.1 8.7 2.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) L_HMGIC_fpl PF10242.9 KER20354.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF5066 PF16728.5 KER20354.1 - 0.053 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) RVT_1 PF00078.27 KER20357.1 - 1.8e-19 70.2 0.0 2.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KER20357.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER20357.1 - 0.037 13.5 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PDZ_6 PF17820.1 KER20358.1 - 1e-22 79.7 0.8 2.4e-12 46.5 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KER20358.1 - 1.2e-21 76.8 0.8 4.5e-09 36.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain ZU5 PF00791.20 KER20358.1 - 2.6e-17 62.9 0.0 1.2e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 ZU5 domain PDZ_2 PF13180.6 KER20358.1 - 1.7e-07 31.4 0.1 0.0014 19.0 0.0 2.9 2 0 0 2 2 2 2 PDZ domain Guanylate_kin PF00625.21 KER20358.1 - 6.2e-05 22.8 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase DUF1217 PF06748.12 KER20358.1 - 0.097 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Metallophos PF00149.28 KER20362.1 - 1.8e-38 133.1 0.1 2.2e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER20362.1 - 4.8e-17 62.1 0.1 2.2e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF61 PF01886.16 KER20362.1 - 0.16 12.0 0.0 16 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF61 Beach PF02138.18 KER20364.1 - 1.6e-122 408.2 0.1 3e-122 407.3 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KER20364.1 - 8.3e-11 41.9 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KER20364.1 - 4e-05 23.0 9.8 0.011 15.0 0.1 4.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4704) DUF4800 PF16057.5 KER20364.1 - 0.0012 18.2 0.1 0.0027 17.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 KER20364.1 - 0.021 14.9 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Claudin_3 PF06653.11 KER20365.1 - 0.00014 21.8 22.7 0.0089 16.0 9.6 2.6 2 2 0 2 2 2 2 Tight junction protein, Claudin-like Ninjurin PF04923.12 KER20365.1 - 0.033 14.1 15.2 0.29 11.1 2.3 2.6 2 1 0 2 2 2 0 Ninjurin HCO3_cotransp PF00955.21 KER20366.1 - 5.3e-223 741.4 11.9 7.4e-223 741.0 11.9 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KER20366.1 - 4.1e-81 272.7 0.0 6.2e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Lon_C PF05362.13 KER20370.1 - 5.8e-62 208.9 0.3 5.3e-47 160.0 0.0 3.9 4 0 0 4 4 4 3 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KER20370.1 - 3.9e-27 95.5 0.1 6.9e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KER20370.1 - 4.1e-24 85.5 0.0 1.6e-23 83.6 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER20370.1 - 3.8e-09 36.7 0.0 8.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KER20370.1 - 3e-07 31.0 0.0 1.5e-05 25.4 0.0 3.3 2 2 1 3 3 3 1 AAA ATPase domain ChlI PF13541.6 KER20370.1 - 1.2e-06 28.4 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 KER20370.1 - 3.9e-06 26.7 0.1 8.5e-05 22.3 0.1 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KER20370.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KER20370.1 - 1.4e-05 24.2 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KER20370.1 - 1.9e-05 24.9 0.3 0.0016 18.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KER20370.1 - 0.00061 19.8 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KER20370.1 - 0.00088 19.2 0.0 0.0075 16.2 0.0 2.3 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KER20370.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 KER20370.1 - 0.0024 18.4 0.4 0.35 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KER20370.1 - 0.006 16.9 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KER20370.1 - 0.015 15.8 0.3 0.069 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KER20370.1 - 0.018 14.2 0.8 0.035 13.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KER20370.1 - 0.025 14.5 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase AAA_33 PF13671.6 KER20370.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KER20370.1 - 0.03 14.2 0.1 0.55 10.1 0.0 2.5 1 1 1 2 2 2 0 NTPase TIP49 PF06068.13 KER20370.1 - 0.041 13.1 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain MIEAP PF16026.5 KER20370.1 - 0.042 14.1 0.2 0.093 12.9 0.2 1.6 1 0 0 1 1 1 0 Mitochondria-eating protein TsaE PF02367.17 KER20370.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KER20370.1 - 0.056 12.9 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KER20370.1 - 0.059 13.1 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain LisH_TPL PF17814.1 KER20370.1 - 0.084 12.5 5.4 0.62 9.8 0.0 3.1 3 0 0 3 3 3 0 LisH-like dimerisation domain AAA_3 PF07726.11 KER20370.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KER20370.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_17 PF13207.6 KER20370.1 - 0.14 12.6 0.6 2.7 8.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER20370.1 - 0.14 12.7 0.3 0.98 9.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 KER20370.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KER20370.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 KER20371.1 - 1.3 8.5 18.3 1.4 8.5 18.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lon_C PF05362.13 KER20372.1 - 1e-22 80.7 0.5 5.2e-22 78.4 0.3 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain RVT_1 PF00078.27 KER20372.1 - 2.2e-08 33.9 0.0 5.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_14 PF13428.6 KER20372.1 - 2.5e-07 31.0 2.7 6.7 7.8 0.1 5.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER20372.1 - 7.7e-05 22.5 1.7 0.48 10.7 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER20372.1 - 0.0001 22.7 3.2 8.7 6.9 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER20372.1 - 0.00034 20.8 3.6 0.5 10.7 1.0 4.5 3 2 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KER20372.1 - 0.0013 18.8 2.0 0.83 9.8 0.0 3.9 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KER20372.1 - 0.02 14.7 0.3 0.18 11.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KER20372.1 - 0.026 14.9 1.2 20 5.8 0.0 4.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KER20372.1 - 0.029 15.0 0.1 52 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ChlI PF13541.6 KER20372.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase TPR_11 PF13414.6 KER20372.1 - 0.083 12.6 1.2 7.2 6.4 0.1 3.3 3 0 0 3 3 3 0 TPR repeat RAWUL PF16207.5 KER20372.1 - 0.1 13.3 0.2 26 5.6 0.0 2.7 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Phage_holin_Dp1 PF16938.5 KER20376.1 - 0.00065 19.9 2.0 1.1 9.5 0.1 2.6 2 0 0 2 2 2 2 Putative phage holin Dp-1 DnaA_N PF11638.8 KER20376.1 - 0.027 14.2 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 DnaA N-terminal domain DUF975 PF06161.11 KER20376.1 - 0.05 13.4 7.0 2.7 7.7 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) zf-CHY PF05495.12 KER20376.1 - 0.093 13.2 10.6 3.2 8.3 1.8 3.0 2 0 0 2 2 2 0 CHY zinc finger DNA_ligase_ZBD PF03119.16 KER20376.1 - 0.18 11.8 4.0 9.6 6.3 0.3 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_7 PF02591.15 KER20376.1 - 0.47 10.7 3.0 25 5.2 0.2 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF418 PF04235.12 KER20376.1 - 3 7.8 8.6 13 5.7 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF418) Pkinase PF00069.25 KER20377.1 - 0.00072 19.0 0.0 0.00077 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PAS_9 PF13426.7 KER20379.1 - 3.6e-18 65.7 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KER20379.1 - 2e-10 40.6 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KER20379.1 - 1.1e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KER20379.1 - 5.5e-07 29.8 0.0 9.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold Ion_trans PF00520.31 KER20380.1 - 1.4e-22 80.2 5.5 2.9e-22 79.1 5.5 1.6 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 KER20380.1 - 3.8e-05 23.7 0.0 7.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 KER20381.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4200 PF13863.6 KER20382.1 - 4e-15 56.3 10.5 4e-15 56.3 10.5 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Lebercilin PF15619.6 KER20382.1 - 0.00083 19.1 3.8 0.00083 19.1 3.8 3.0 3 1 0 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease MCM_N PF14551.6 KER20382.1 - 0.026 15.1 1.0 0.086 13.4 0.5 2.1 2 0 0 2 2 2 0 MCM N-terminal domain Baculo_p24 PF05073.12 KER20382.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.8 2 1 0 2 2 2 0 Baculovirus P24 capsid protein ZapB PF06005.12 KER20382.1 - 0.29 11.6 19.5 0.44 11.0 0.9 4.4 4 1 0 4 4 4 0 Cell division protein ZapB EF-hand_7 PF13499.6 KER20383.1 - 3.5e-17 62.6 5.2 4.8e-10 39.7 0.2 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KER20383.1 - 1.2e-11 43.5 5.6 0.00028 20.6 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 KER20383.1 - 7.2e-11 40.8 8.0 1.2e-05 24.5 0.4 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KER20383.1 - 5.1e-08 32.1 3.8 0.00084 18.7 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KER20383.1 - 7e-06 25.8 6.6 0.00084 19.1 0.4 3.0 3 1 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER20383.1 - 0.0003 21.1 0.0 0.004 17.5 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region HTH_23 PF13384.6 KER20383.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KER20383.1 - 0.018 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KER20383.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF3791 PF12668.7 KER20383.1 - 0.12 12.4 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) DNA_pol_phi PF04931.13 KER20384.1 - 0.018 13.1 13.4 0.02 13.0 13.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KER20384.1 - 0.039 13.1 19.6 0.042 13.0 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KER20384.1 - 0.044 13.5 2.4 0.06 13.0 2.4 1.2 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 KER20384.1 - 0.14 10.4 6.4 0.13 10.5 6.4 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KER20384.1 - 0.43 10.0 7.0 0.41 10.0 7.0 1.1 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 KER20384.1 - 0.5 8.9 6.3 0.48 8.9 6.3 1.0 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.11 KER20384.1 - 0.65 8.5 7.1 0.58 8.6 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KER20384.1 - 0.68 9.2 5.3 0.62 9.3 5.3 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KER20384.1 - 1.3 7.2 8.2 1.4 7.1 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 KER20384.1 - 2.3 7.8 8.5 2.6 7.6 8.5 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 KER20384.1 - 2.4 8.0 9.8 3.2 7.6 9.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KER20384.1 - 3 8.3 26.9 4.5 7.7 26.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KER20384.1 - 4.2 7.0 22.4 6.1 6.5 22.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tom22 PF04281.13 KER20384.1 - 4.4 7.1 7.0 6.4 6.6 7.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2722 PF10846.8 KER20384.1 - 5 5.9 6.1 5.3 5.9 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 KER20384.1 - 8 5.7 25.2 14 4.9 25.2 1.3 1 0 0 1 1 1 0 NOA36 protein RSN1_7TM PF02714.15 KER20385.1 - 8.8e-32 110.5 5.6 8.8e-32 110.5 5.6 2.3 2 1 1 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KER20385.1 - 2.4e-09 37.7 0.0 7e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter CPBP PF02517.16 KER20385.1 - 0.011 16.1 1.3 0.011 16.1 1.3 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease DUF3169 PF11368.8 KER20385.1 - 0.15 11.6 1.3 0.32 10.5 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Keratin_B2_2 PF13885.6 KER20385.1 - 1 9.4 10.4 0.13 12.2 3.8 2.4 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein adh_short PF00106.25 KER20388.1 - 3.2e-15 56.1 0.0 7e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER20388.1 - 1.2e-07 31.5 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER20389.1 - 1e-05 25.1 0.1 1.5e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER20389.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KER20390.1 - 4.7e-22 78.4 0.1 9.3e-20 70.9 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER20390.1 - 2e-10 40.6 0.0 8.4e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER20390.1 - 9.4e-05 22.4 0.2 0.00018 21.5 0.0 1.5 2 0 0 2 2 2 1 KR domain Glyco_trans_4_4 PF13579.6 KER20390.1 - 0.079 13.4 0.5 6.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Exo_endo_phos_2 PF14529.6 KER20391.1 - 6.9e-05 22.7 0.0 0.00041 20.2 0.0 2.0 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase Microtub_bd PF16796.5 KER20392.1 - 2.1e-07 31.0 0.0 7.3e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding GAS PF13851.6 KER20392.1 - 1.5 8.1 21.5 1.5 8.1 20.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 KER20393.1 - 5.6e-08 32.1 12.2 5.6e-08 32.1 12.2 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily NPV_P10 PF05531.12 KER20396.1 - 0.0092 16.4 0.3 0.0092 16.4 0.3 5.0 4 1 1 5 5 5 1 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 KER20396.1 - 0.3 11.4 13.7 1.5 9.1 0.5 4.0 3 1 0 3 3 3 0 TSC-22/dip/bun family RPW8 PF05659.11 KER20396.1 - 0.32 10.7 12.3 1.4 8.6 0.6 4.0 2 1 2 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APG6_N PF17675.1 KER20396.1 - 1 9.9 48.1 5.5 7.5 8.8 3.6 2 2 2 4 4 4 0 Apg6 coiled-coil region ATG16 PF08614.11 KER20396.1 - 1.1 9.5 52.6 0.89 9.7 43.0 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COMP PF11598.8 KER20396.1 - 1.4 9.4 7.5 15 6.1 0.5 3.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein UPF0242 PF06785.11 KER20396.1 - 1.5 8.9 35.5 1.7 8.7 9.0 3.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Vac_Fusion PF02346.16 KER20396.1 - 2.9 7.6 7.3 7.7 6.2 0.4 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 GP57 PF17594.2 KER20396.1 - 3.5 7.4 7.6 2.2 8.1 0.2 3.0 3 0 0 3 3 3 0 Phage Tail fiber assembly helper gene product 57 Uso1_p115_C PF04871.13 KER20396.1 - 3.9 7.9 44.8 3.6 8.0 9.4 3.4 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.11 KER20396.1 - 4.1 6.1 41.5 0.97 8.2 10.4 2.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SKA1 PF07160.12 KER20396.1 - 5.2 6.9 30.1 0.3 10.9 4.2 3.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Jnk-SapK_ap_N PF09744.9 KER20396.1 - 5.3 7.2 47.4 0.74 10.0 4.3 4.1 1 1 2 4 4 4 0 JNK_SAPK-associated protein-1 MIP-T3 PF10243.9 KER20397.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain Spc7 PF08317.11 KER20397.1 - 1.3 7.8 27.4 0.074 11.9 19.5 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Shugoshin_N PF07558.11 KER20397.1 - 3.5 7.6 6.7 0.67 9.9 0.4 3.2 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Guanylate_kin PF00625.21 KER20399.1 - 3.5e-27 95.3 0.4 2.8e-26 92.3 0.0 2.5 2 1 0 2 2 2 1 Guanylate kinase Atrophin-1 PF03154.15 KER20399.1 - 0.0042 15.5 1.1 0.0042 15.5 1.1 2.5 3 0 0 3 3 3 2 Atrophin-1 family DUF3247 PF11607.8 KER20399.1 - 0.027 14.7 0.1 22 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3247) V-ATPase_G_2 PF16999.5 KER20399.1 - 0.35 11.3 20.7 0.43 11.0 1.1 3.6 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit FAM221 PF14753.6 KER20401.1 - 2.8e-34 118.4 5.2 3.6e-34 118.1 5.2 1.1 1 0 0 1 1 1 1 Protein FAM221A/B GTP-bdg_M PF16360.5 KER20401.1 - 0.041 14.5 0.1 0.067 13.8 0.1 1.4 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region LuxT_C PF18285.1 KER20402.1 - 0.13 12.8 0.1 0.48 11.0 0.0 1.8 1 1 1 2 2 2 0 Tetracycline repressor LuxT C-terminal domain Asp PF00026.23 KER20404.1 - 6.9e-46 157.1 0.0 1.6e-22 80.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER20404.1 - 4.7e-07 30.2 0.2 6.7e-06 26.4 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KER20404.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal PH PF00169.29 KER20405.1 - 1.4e-11 44.8 0.1 1.8e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KER20405.1 - 0.00042 20.7 0.1 0.00053 20.4 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KER20405.1 - 0.002 18.4 0.0 0.0024 18.1 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain Acyl-CoA_dh_1 PF00441.24 KER20409.1 - 2e-40 138.4 1.7 2.8e-40 138.0 1.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KER20409.1 - 1.1e-28 99.2 0.1 1.9e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KER20409.1 - 8.7e-12 45.5 0.0 1.4e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KER20409.1 - 1.3e-10 41.9 0.1 8.9e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KER20409.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ig_3 PF13927.6 KER20410.1 - 1.2e-39 134.7 8.1 5.4e-09 36.5 0.1 7.5 7 1 0 7 7 7 5 Immunoglobulin domain I-set PF07679.16 KER20410.1 - 3e-38 129.8 0.1 3.9e-10 39.7 0.0 7.7 6 3 0 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.6 KER20410.1 - 7.8e-26 90.2 1.7 1.8e-07 31.4 0.0 7.2 7 1 0 7 7 7 3 Immunoglobulin domain V-set PF07686.17 KER20410.1 - 2.1e-24 85.8 11.2 0.006 16.7 0.0 8.5 5 4 2 7 7 7 6 Immunoglobulin V-set domain ig PF00047.25 KER20410.1 - 7.4e-23 80.5 3.5 7.5e-05 22.8 0.2 6.7 6 2 0 6 6 6 4 Immunoglobulin domain Ig_4 PF16680.5 KER20410.1 - 6e-10 39.2 1.7 0.00098 19.3 0.0 4.6 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KER20410.1 - 4.1e-09 36.7 0.7 0.032 14.6 0.0 4.4 4 0 0 4 4 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 KER20410.1 - 1.5e-07 31.4 0.1 0.26 11.4 0.0 4.7 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KER20410.1 - 4.3e-07 29.4 0.2 0.36 10.4 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain C2-set PF05790.15 KER20410.1 - 0.00042 20.5 0.1 0.5 10.6 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin C2-set domain C2-set_2 PF08205.12 KER20410.1 - 0.00079 19.5 0.0 0.42 10.7 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KER20411.1 - 9.4e-08 32.3 10.8 0.86 10.0 0.0 8.5 8 1 0 8 8 8 3 Fibronectin type III domain Salp15 PF12115.8 KER20413.1 - 0.0015 18.9 7.6 7.1 7.1 0.2 4.1 3 0 0 3 3 3 3 Salivary protein of 15kDa inhibits CD4+ T cell activation NOG1 PF06858.14 KER20413.1 - 0.0027 17.4 0.0 30 4.5 0.0 3.4 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) DUF807 PF05660.11 KER20413.1 - 0.11 12.4 0.2 1.3e+02 2.5 0.0 3.5 3 0 0 3 3 3 0 Coxiella burnetii protein of unknown function (DUF807) CPT_N PF16484.5 KER20413.1 - 0.12 12.3 0.2 31 4.7 0.0 2.7 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus UPF0061 PF02696.14 KER20413.1 - 0.28 9.9 1.6 45 2.6 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized ACR, YdiU/UPF0061 family PAS_11 PF14598.6 KER20413.1 - 0.51 10.5 9.0 31 4.7 0.3 3.5 3 0 0 3 3 3 0 PAS domain zf-HC3 PF16827.5 KER20413.1 - 0.58 10.4 7.5 63 3.9 0.2 4.2 3 0 0 3 3 3 0 zinc-finger TSP_1 PF00090.19 KER20414.1 - 2.4e-10 40.5 39.5 4.3e-09 36.5 4.2 5.2 5 0 0 5 5 5 3 Thrombospondin type 1 domain adh_short PF00106.25 KER20416.1 - 6.4e-30 104.1 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER20416.1 - 3.4e-21 75.9 0.1 4.8e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER20416.1 - 0.0033 17.3 0.4 0.0069 16.3 0.2 1.6 2 0 0 2 2 2 1 KR domain CRR7 PF12095.8 KER20418.1 - 0.26 11.7 1.2 0.67 10.4 0.3 2.1 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF4599 PF15371.6 KER20419.1 - 0.016 15.7 0.2 0.037 14.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4599) RseA_C PF03873.13 KER20420.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain SH3_10 PF17902.1 KER20424.1 - 3.5e-06 27.0 0.1 1.2e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 SH3 domain Plectin PF00681.20 KER20424.1 - 0.0042 16.9 0.5 0.57 10.1 0.0 3.3 3 0 0 3 3 3 1 Plectin repeat DUF5130 PF17174.4 KER20424.1 - 0.33 11.2 27.3 1.2 9.4 0.2 8.9 8 3 3 11 11 11 0 Domain of unknown function (DUF5130) DUF4709 PF15821.5 KER20424.1 - 0.61 10.4 4.5 3.8 7.8 0.5 4.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Actin PF00022.19 KER20425.1 - 2.9e-95 319.3 0.0 1.2e-94 317.3 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER20426.1 - 9.3e-22 77.2 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.19 KER20427.1 - 4.8e-88 295.5 0.0 2.1e-87 293.4 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER20428.1 - 3.6e-152 506.7 0.0 1.2e-151 505.0 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER20429.1 - 1.8e-135 451.7 0.0 2e-132 441.7 0.0 2.7 1 1 0 1 1 1 1 Actin BAH PF01426.18 KER20432.1 - 1.5e-13 50.7 1.1 4.3e-12 46.0 1.1 2.3 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 KER20432.1 - 0.037 14.8 0.2 0.19 12.5 0.2 2.3 1 1 0 1 1 1 0 ELM2 domain TIP120 PF08623.10 KER20434.1 - 1.3e-50 171.5 5.9 4.8e-50 169.6 0.6 3.6 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KER20434.1 - 5.2e-13 49.2 23.9 0.00018 21.8 0.1 10.3 9 2 0 9 9 9 3 HEAT repeats HEAT PF02985.22 KER20434.1 - 7.8e-10 38.2 28.8 0.47 10.9 0.0 11.6 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.6 KER20434.1 - 5.7e-07 29.9 31.2 0.025 15.1 0.0 10.0 10 0 0 10 10 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KER20434.1 - 3.1e-06 27.7 0.1 0.59 10.8 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KER20434.1 - 1.5e-05 25.2 0.0 0.016 15.5 0.0 4.0 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain Ipi1_N PF12333.8 KER20434.1 - 0.0012 19.4 4.0 0.033 14.8 0.1 4.3 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 KER20434.1 - 0.012 15.2 1.1 3.2 7.2 0.1 3.1 2 0 0 2 2 2 0 CLASP N terminal NopRA1 PF16201.5 KER20434.1 - 0.046 13.3 0.2 1.6 8.3 0.1 3.8 2 1 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 KER20434.1 - 0.14 12.9 6.9 17 6.5 0.1 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat PCDO_beta_N PF12391.8 KER20435.1 - 0.074 12.7 1.7 0.095 12.3 0.1 1.9 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal HLH PF00010.26 KER20436.1 - 9.1e-14 51.2 0.1 2e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DSHCT PF08148.12 KER20439.1 - 2e-37 128.4 0.0 4.3e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KER20439.1 - 1.4e-19 71.1 0.1 1.5e-10 41.5 0.1 3.3 1 1 2 3 3 3 3 rRNA-processing arch domain DEAD PF00270.29 KER20439.1 - 4.3e-18 65.7 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER20439.1 - 1.2e-07 32.1 0.1 7.2e-06 26.3 0.1 3.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER20439.1 - 3.5e-05 23.9 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER20439.1 - 0.0083 16.4 0.0 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KER20439.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KER20439.1 - 0.11 12.8 0.1 4.8 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain zf-H2C2_2 PF13465.6 KER20440.1 - 4.3e-06 26.9 0.3 4.3e-06 26.9 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER20440.1 - 0.0026 18.4 17.1 4.7 8.3 0.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KER20440.1 - 0.017 15.6 21.8 0.11 13.1 0.3 5.8 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 KER20440.1 - 0.076 12.7 0.1 0.076 12.7 0.1 3.6 2 1 3 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KER20440.1 - 0.47 10.8 6.4 8.3 6.8 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Terminase_GpA PF05876.12 KER20440.1 - 3.2 6.2 8.4 0.3 9.6 0.1 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) ERCC4 PF02732.15 KER20441.1 - 0.022 14.9 0.3 0.049 13.8 0.3 1.6 1 0 0 1 1 1 0 ERCC4 domain Fe_hyd_lg_C PF02906.14 KER20443.1 - 6.6e-46 156.9 0.0 5.8e-44 150.6 0.0 3.0 1 1 1 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain UQ_con PF00179.26 KER20444.1 - 2e-32 111.7 0.0 3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KER20444.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KER20444.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KER20444.1 - 0.076 13.3 0.1 0.17 12.2 0.1 1.7 1 1 0 1 1 1 0 RWD domain GTP_EFTU PF00009.27 KER20445.1 - 1.6e-32 112.6 3.6 2e-31 109.0 3.6 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KER20445.1 - 1.5e-25 89.3 0.0 5.9e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KER20445.1 - 1.6e-08 34.6 0.3 4.4e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KER20445.1 - 0.00021 21.1 0.8 0.028 14.2 0.3 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KER20445.1 - 0.0088 16.0 0.7 0.41 10.5 0.3 3.1 2 1 1 3 3 3 1 RsgA GTPase Ras PF00071.22 KER20445.1 - 0.01 15.4 0.1 0.047 13.3 0.1 2.0 1 1 0 1 1 1 0 Ras family FeoB_N PF02421.18 KER20445.1 - 0.011 15.3 0.7 0.23 10.9 0.7 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 KER20445.1 - 0.056 13.7 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 KER20445.1 - 0.083 12.9 0.1 0.24 11.4 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KER20445.1 - 0.1 12.7 0.3 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Dynamin family Glyco_transf_92 PF01697.27 KER20446.1 - 4.1e-25 88.9 1.2 5.7e-25 88.4 1.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KER20446.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KER20447.1 - 2.3e-14 53.7 0.0 3.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Sporozoite_P67 PF05642.11 KER20449.1 - 2.4 6.1 5.0 3.1 5.8 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.12 KER20449.1 - 8.2 4.9 6.8 11 4.5 6.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MH2 PF03166.14 KER20450.1 - 5.2e-72 242.0 0.0 8e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KER20450.1 - 1.3e-35 121.7 0.3 2.2e-35 121.0 0.3 1.4 1 0 0 1 1 1 1 MH1 domain Peptidase_C13 PF01650.18 KER20452.1 - 1.4e-94 316.4 2.4 1.9e-94 316.0 2.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20452.1 - 0.0053 16.7 0.1 0.0073 16.3 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER20453.1 - 9.1e-83 277.7 0.6 1.3e-82 277.1 0.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20453.1 - 0.002 18.1 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER20454.1 - 1.1e-90 303.6 1.2 1.7e-90 303.0 1.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20454.1 - 0.00053 20.0 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER20455.1 - 2.5e-14 53.4 0.3 3.2e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family YlbD_coat PF14071.6 KER20455.1 - 0.066 13.5 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative coat protein Peptidase_M16 PF00675.20 KER20456.1 - 1.2e-16 61.1 0.0 2.5e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KER20456.1 - 1.2e-09 38.4 0.0 9.1e-07 29.1 0.0 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain Headcase PF16002.5 KER20457.1 - 1.4e-44 151.9 11.4 4.1e-25 88.4 0.0 4.5 4 0 0 4 4 4 4 Headcase protein HECA PF15353.6 KER20457.1 - 0.0012 19.0 1.9 0.0012 19.0 1.9 2.1 2 0 0 2 2 2 1 Headcase protein family homologue Ldl_recept_a PF00057.18 KER20463.1 - 0.0031 17.7 3.5 0.0031 17.7 3.5 2.9 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A RRM_1 PF00076.22 KER20464.1 - 9.2e-13 47.8 0.0 1.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KER20464.1 - 3.3e-08 34.0 0.1 3.3e-08 34.0 0.1 2.5 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 QRPTase_C PF01729.19 KER20465.1 - 3.3e-12 46.5 0.0 5.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain SOG2 PF10428.9 KER20465.1 - 4 6.5 10.2 5.3 6.1 10.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Asp PF00026.23 KER20470.1 - 3.4e-43 148.3 0.0 3.8e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER20470.1 - 3.7e-13 50.1 0.3 2e-10 41.2 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KER20470.1 - 0.056 14.0 0.0 3.8 8.1 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER20470.1 - 0.13 12.9 0.0 5.4 7.7 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease HAUS6_N PF14661.6 KER20471.1 - 3.2e-05 23.6 0.0 9.7e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus WW PF00397.26 KER20472.1 - 0.00043 20.3 2.2 0.00043 20.3 2.2 2.0 2 0 0 2 2 2 1 WW domain WD40 PF00400.32 KER20476.1 - 4.6e-07 30.4 1.9 5 8.1 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20476.1 - 0.001 19.3 0.0 0.16 12.3 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain XRCC1_N PF01834.16 KER20478.1 - 3.1e-45 153.8 0.1 5.5e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT_2 PF16589.5 KER20478.1 - 3.9e-18 65.6 0.0 3.7e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KER20478.1 - 3e-17 62.8 0.0 7e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KER20478.1 - 9.7e-10 38.3 0.0 9.4e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain RVT_1 PF00078.27 KER20478.1 - 3.1e-08 33.4 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LIG3_BRCT PF16759.5 KER20478.1 - 6.1e-06 26.4 0.0 0.00039 20.6 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain SDA1 PF05285.12 KER20478.1 - 0.0094 15.4 10.2 0.015 14.7 10.2 1.3 1 0 0 1 1 1 1 SDA1 RTT107_BRCT_5 PF16770.5 KER20478.1 - 0.11 12.4 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF4637 PF15470.6 KER20478.1 - 0.75 9.5 9.2 1.9 8.2 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2574 PF10836.8 KER20478.1 - 1.1 9.1 3.7 1.2 9.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Nop14 PF04147.12 KER20478.1 - 1.8 6.7 16.4 2.7 6.1 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 KER20478.1 - 3.3 5.9 8.9 5.2 5.2 8.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 KER20478.1 - 7.2 5.8 10.8 13 5.0 10.8 1.4 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 KER20479.1 - 1.3e-63 214.9 0.0 1.6e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20479.1 - 2.5e-31 108.9 0.0 3.6e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER20479.1 - 7.5e-07 28.4 0.0 1.9e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KER20479.1 - 0.00025 21.1 0.2 0.0019 18.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER20479.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER20479.1 - 0.06 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KER20479.1 - 0.18 11.4 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF4705 PF15788.5 KER20481.1 - 0.092 13.0 0.7 0.18 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) DUF3591 PF12157.8 KER20482.1 - 9.1e-144 479.4 0.0 3e-143 477.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KER20482.1 - 1.9e-39 133.6 1.9 3.2e-19 68.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 KER20482.1 - 6.1e-08 32.4 1.1 1.6e-07 31.0 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle TBP-binding PF09247.11 KER20482.1 - 3.1e-05 24.1 0.4 8.8e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 TATA box-binding protein binding MdcG PF10620.9 KER20482.1 - 0.027 14.3 0.3 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG dsrm PF00035.26 KER20483.1 - 0.025 15.3 0.0 6.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif C12orf66_like PF09404.10 KER20484.1 - 2.3e-52 178.3 0.0 5.6e-40 137.5 0.0 2.1 2 0 0 2 2 2 2 KICSTOR complex C12orf66 like Ten1_2 PF15490.6 KER20484.1 - 3e-06 26.9 0.0 7.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit IFT46_B_C PF12317.8 KER20484.1 - 0.0034 17.2 0.6 2.4 7.9 0.1 2.3 2 0 0 2 2 2 2 Intraflagellar transport complex B protein 46 C terminal RabGAP-TBC PF00566.18 KER20486.1 - 2.4e-34 118.9 0.9 4.1e-34 118.1 0.4 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Peptidase_C42 PF05533.12 KER20488.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 DUF5397 PF17375.2 KER20488.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Ig_3 PF13927.6 KER20490.1 - 2.4e-53 178.6 0.0 3.5e-12 46.8 0.0 6.5 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KER20490.1 - 2.8e-46 155.5 0.0 7.9e-13 48.3 0.0 6.0 5 1 1 6 6 6 5 Immunoglobulin I-set domain ig PF00047.25 KER20490.1 - 3.6e-34 116.8 0.0 4.1e-06 26.9 0.0 6.4 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KER20490.1 - 2.9e-33 114.0 0.0 7.5e-08 32.6 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KER20490.1 - 8.7e-26 90.2 0.6 1.1e-05 25.5 0.0 8.4 5 4 0 5 5 5 4 Immunoglobulin V-set domain fn3 PF00041.21 KER20490.1 - 2.3e-17 63.1 0.5 6.3e-07 29.7 0.0 5.4 4 1 0 4 4 4 4 Fibronectin type III domain C2-set_2 PF08205.12 KER20490.1 - 2.5e-10 40.3 0.4 0.075 13.1 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KER20490.1 - 6.8e-08 32.0 0.0 0.35 10.5 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain V-set_CD47 PF08204.11 KER20490.1 - 0.0041 17.1 0.0 5.9 6.9 0.0 3.1 3 0 0 3 3 3 2 CD47 immunoglobulin-like domain C1-set PF07654.15 KER20490.1 - 0.014 15.7 0.0 0.24 11.8 0.0 3.0 2 0 0 2 2 2 0 Immunoglobulin C1-set domain Herpes_gE PF02480.16 KER20490.1 - 0.08 11.7 0.0 6.3 5.4 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E LLGL PF08366.13 KER20493.1 - 5.8e-17 61.9 0.0 1.6e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 LLGL2 Synaptobrevin PF00957.21 KER20493.1 - 0.0001 22.0 0.2 0.00017 21.3 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 KER20493.1 - 0.00014 22.6 4.3 0.02 15.8 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Lgl_C PF08596.10 KER20493.1 - 0.18 10.5 0.0 0.41 9.3 0.0 1.6 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal bZIP_Maf PF03131.17 KER20497.1 - 9.5e-06 26.1 7.8 1.6e-05 25.3 7.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KER20497.1 - 0.089 12.9 12.8 0.21 11.7 12.3 1.9 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 KER20497.1 - 0.091 12.9 9.8 0.21 11.7 9.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper US30 PF17624.2 KER20497.1 - 0.76 8.8 5.0 1.7 7.6 5.0 1.5 1 0 0 1 1 1 0 Family of unknown function DUF4140 PF13600.6 KER20497.1 - 3.8 8.0 9.6 75 3.8 4.6 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 KER20499.1 - 8.6e-150 487.7 48.1 1.1e-17 64.4 0.1 8.7 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER20499.1 - 9.6e-107 348.1 42.7 2e-14 53.8 0.2 11.5 5 4 8 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 KER20499.1 - 7.9e-98 317.0 44.7 1.4e-09 37.9 0.1 17.2 16 1 1 17 17 17 16 Ankyrin repeat Ank_5 PF13857.6 KER20499.1 - 4.8e-95 310.4 31.0 1.4e-10 41.2 0.1 14.6 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER20499.1 - 3.3e-85 269.7 29.5 5.5e-06 26.3 0.0 17.4 17 0 0 17 17 17 16 Ankyrin repeat UPA_2 PF17809.1 KER20499.1 - 1.6e-43 147.7 0.0 5.7e-43 145.9 0.0 2.0 2 0 0 2 2 2 1 UPA domain ZU5 PF00791.20 KER20499.1 - 4.7e-35 119.8 0.4 3.2e-23 81.9 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 KER20499.1 - 2.1e-10 40.6 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Death domain MIF4G_like PF09088.11 KER20502.1 - 2.5e-27 95.9 0.6 2.1e-25 89.6 0.1 2.4 1 1 1 2 2 2 2 MIF4G like MIF4G_like_2 PF09090.11 KER20502.1 - 4.1e-21 75.6 1.5 1.3e-17 64.2 0.4 3.4 2 1 0 2 2 2 2 MIF4G like MIF4G PF02854.19 KER20502.1 - 8.1e-05 22.3 0.0 0.00098 18.8 0.0 2.2 1 1 0 1 1 1 1 MIF4G domain MFS_1 PF07690.16 KER20503.1 - 2.5e-20 72.7 33.9 1.4e-15 57.1 24.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Drf_GBD PF06371.13 KER20507.1 - 1.2e-15 57.6 1.1 1.6e-15 57.1 1.1 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain RAG1_imp_bd PF12560.8 KER20507.1 - 0.013 15.1 1.2 0.021 14.4 1.2 1.2 1 0 0 1 1 1 0 RAG1 importin binding DUF5449 PF17528.2 KER20509.1 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5449) DnaJ PF00226.31 KER20512.1 - 1.6e-21 76.2 0.6 2.9e-21 75.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Hydin_ADK PF17213.3 KER20513.1 - 6.7e-17 62.4 0.3 2e-10 41.3 0.0 3.7 2 2 1 3 3 3 2 Hydin Adenylate kinase-like domain PapD-like PF14874.6 KER20513.1 - 2.5e-12 46.8 8.0 0.029 14.5 0.0 7.4 8 0 0 8 8 8 3 Flagellar-associated PapD-like ASH PF15780.5 KER20513.1 - 6.2e-11 42.4 5.6 0.0072 16.5 0.0 8.0 8 1 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KER20513.1 - 1.5e-09 37.7 0.2 1.3 8.9 0.0 7.0 7 0 0 7 7 7 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 KER20513.1 - 2.3e-05 24.4 0.0 11 6.1 0.0 6.9 8 1 0 8 8 8 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 KER20513.1 - 0.0049 17.1 2.1 0.13 12.6 0.0 4.2 5 1 0 5 5 5 1 Transmembrane protein 131-like DUF5001 PF16392.5 KER20513.1 - 0.012 15.5 1.0 21 5.1 0.0 5.3 6 0 0 6 6 6 0 Ig-like domain ADK PF00406.22 KER20513.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase LIFR_D2 PF17971.1 KER20513.1 - 0.17 12.1 0.0 24 5.1 0.0 2.6 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain WD40 PF00400.32 KER20514.1 - 1.1e-15 57.8 13.1 0.00044 21.0 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KER20514.1 - 1.3e-09 38.2 0.0 3.3e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SURF2 PF05477.11 KER20514.1 - 0.27 10.9 4.2 4.3 7.0 1.7 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) MMM1 PF10296.9 KER20515.1 - 0.00046 19.3 1.7 0.0025 16.9 0.0 2.5 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Phage_holin_3_6 PF07332.11 KER20515.1 - 4.9 7.2 9.3 8.8 6.4 9.3 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Haspin_kinase PF12330.8 KER20516.1 - 7.8e-56 189.6 0.1 2.4e-43 148.5 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase PF00069.25 KER20516.1 - 0.019 14.3 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RVT_1 PF00078.27 KER20516.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 KER20516.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER20516.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ER_lumen_recept PF00810.18 KER20518.1 - 2e-48 164.9 12.0 2e-48 164.9 12.0 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor HPS6 PF15702.5 KER20519.1 - 0.068 11.2 0.0 0.068 11.2 0.0 1.0 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein Ribosomal_S5 PF00333.20 KER20521.1 - 3.5e-16 58.9 1.8 6.8e-16 58.0 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KER20521.1 - 1.4e-14 53.3 0.0 4.2e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain UPF0172 PF03665.13 KER20522.1 - 9.8e-35 120.3 0.2 1.2e-34 120.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) PAXNEB PF05625.11 KER20523.1 - 5.6e-40 137.6 0.0 7.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Brix PF04427.18 KER20524.1 - 1.3e-25 90.6 0.4 2.5e-25 89.7 0.4 1.5 1 0 0 1 1 1 1 Brix domain Ribosomal_L21p PF00829.21 KER20526.1 - 9.7e-21 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Peptidase_C13 PF01650.18 KER20527.1 - 1.9e-30 106.2 1.1 7.4e-21 74.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C13 family Tombus_P33 PF08500.10 KER20527.1 - 0.15 12.0 0.2 30 4.6 0.0 2.8 3 0 0 3 3 3 0 Tombusvirus p33 Peptidase_C13 PF01650.18 KER20528.1 - 2.6e-30 105.8 1.3 3.2e-30 105.5 1.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER20529.1 - 1.5e-81 273.7 0.7 2.4e-81 273.0 0.7 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20529.1 - 0.0052 16.8 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER20530.1 - 3.8e-99 331.4 5.2 4.2e-66 223.1 0.2 2.4 2 0 0 2 2 2 2 Peptidase C13 family Integrase_H2C2 PF17921.1 KER20530.1 - 5.2e-08 32.9 0.4 1.3e-07 31.6 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Peptidase_C14 PF00656.22 KER20530.1 - 0.0099 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Caspase domain rve PF00665.26 KER20530.1 - 0.028 14.6 1.2 0.26 11.5 0.0 2.6 2 1 0 2 2 2 0 Integrase core domain HIT PF01230.23 KER20530.1 - 0.069 13.9 1.8 2.5 8.9 0.3 3.2 2 1 1 3 3 3 0 HIT domain Omp28 PF11551.8 KER20530.1 - 0.17 11.7 1.4 10 5.9 0.1 2.3 1 1 1 2 2 2 0 Outer membrane protein Omp28 Peptidase_C13 PF01650.18 KER20531.1 - 3.1e-72 243.2 0.4 4.9e-72 242.5 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20531.1 - 0.00048 20.2 0.1 0.0011 19.0 0.1 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER20531.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 Golgin_A5 PF09787.9 KER20532.1 - 0.0012 18.3 10.6 0.0012 18.3 10.6 10.2 9 1 2 11 11 11 3 Golgin subfamily A member 5 MobC PF05713.11 KER20532.1 - 2.7 8.5 9.8 61 4.2 0.1 5.4 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) NRN1 PF15056.6 KER20532.1 - 6.1 7.0 8.1 0.88 9.7 1.0 3.2 3 0 0 3 3 3 0 Neuritin protein family RabGAP-TBC PF00566.18 KER20533.1 - 5.1e-45 153.8 0.7 5.1e-45 153.8 0.7 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 KER20533.1 - 1.4e-13 51.8 0.1 4e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Kinesin protein CENP-F_leu_zip PF10473.9 KER20533.1 - 0.0092 16.0 10.0 0.022 14.8 10.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KER20533.1 - 0.028 15.0 11.2 0.12 13.1 6.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Not3 PF04065.15 KER20533.1 - 0.068 12.6 4.6 0.12 11.8 4.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component GBP_C PF02841.14 KER20533.1 - 0.11 11.8 10.8 0.18 11.2 10.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mod_r PF07200.13 KER20533.1 - 0.13 12.4 10.9 0.43 10.7 10.9 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 KER20533.1 - 0.32 11.2 9.2 0.81 9.9 9.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gp-FAR-1 PF05823.12 KER20533.1 - 0.43 10.9 3.2 0.9 9.9 1.1 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GvpL_GvpF PF06386.11 KER20533.1 - 0.86 9.5 5.3 2.1 8.2 5.3 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 KER20533.1 - 1 7.2 4.2 1.5 6.6 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 KER20533.1 - 1.6 8.8 10.7 8.6 6.4 0.1 2.7 1 1 1 2 2 2 0 FlxA-like protein HALZ PF02183.18 KER20533.1 - 1.6 9.0 5.0 5.1 7.4 0.2 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 KER20533.1 - 1.7 9.0 10.7 3.8 7.9 10.7 1.6 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 KER20533.1 - 7.5 5.8 8.4 15 4.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 KER20533.1 - 9.4 6.3 16.3 0.13 12.3 1.8 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BBS2_C PF14782.6 KER20534.1 - 1.3e-76 258.2 2.9 2.2e-60 204.6 0.2 3.7 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 KER20534.1 - 7.4e-24 83.9 0.7 1.3e-08 34.8 0.0 4.7 5 0 0 5 5 5 3 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 KER20534.1 - 1.9e-08 34.1 0.0 7.2e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 KER20534.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 FG-GAP repeat FAM184 PF15665.5 KER20534.1 - 0.13 12.1 0.8 0.26 11.1 0.8 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Gamma-thionin PF00304.20 KER20535.1 - 0.21 11.9 16.7 0.32 11.3 5.6 2.4 1 1 1 2 2 2 0 Gamma-thionin family Ole-e-6 PF09253.10 KER20535.1 - 0.88 9.6 26.8 0.22 11.5 5.5 3.1 1 1 2 3 3 3 0 Pollen allergen ole e 6 TTL PF03133.15 KER20537.1 - 3.1e-22 79.1 0.1 1.5e-10 40.7 0.2 2.4 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER20537.1 - 0.0053 16.0 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp Big_4 PF07532.11 KER20537.1 - 0.14 12.0 0.2 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) DUF3898 PF13037.6 KER20538.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) GTP_EFTU PF00009.27 KER20539.1 - 2.9e-22 79.2 0.0 5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER20539.1 - 0.00042 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KER20539.1 - 0.00098 19.5 0.1 0.0035 17.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KER20539.1 - 0.017 15.5 0.0 0.043 14.1 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu C-terminal domain Dmrt1 PF12374.8 KER20539.1 - 0.022 15.2 1.8 0.064 13.7 1.8 1.8 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 PduV-EutP PF10662.9 KER20539.1 - 0.088 12.6 0.0 29 4.4 0.0 3.2 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KER20539.1 - 0.11 12.5 0.1 0.56 10.2 0.1 2.1 1 1 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 KER20539.1 - 0.17 11.8 0.2 6.8 6.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase RQC PF09382.10 KER20541.1 - 0.052 13.3 0.0 0.33 10.7 0.0 2.4 3 0 0 3 3 3 0 RQC domain PP2C PF00481.21 KER20543.1 - 3.3e-51 174.4 0.2 4.9e-51 173.8 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SDA1 PF05285.12 KER20543.1 - 0.085 12.3 8.9 0.13 11.6 8.9 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KER20543.1 - 0.18 9.9 24.0 0.28 9.2 24.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KER20543.1 - 0.25 10.6 8.9 0.43 9.9 8.9 1.3 1 0 0 1 1 1 0 BUD22 TAD2 PF18521.1 KER20544.1 - 0.0028 17.5 0.7 4 7.6 0.1 2.7 2 0 0 2 2 2 2 Transactivation domain 2 RebB PF11747.8 KER20544.1 - 1.4 9.1 3.2 34 4.6 0.2 2.4 2 0 0 2 2 2 0 Killing trait CFAP91 PF14738.6 KER20545.1 - 1.7e-54 184.1 11.2 1.7e-54 184.1 11.2 3.2 2 1 1 3 3 3 1 Cilia- and flagella-associated protein 91 CaM-KIIN PF15170.6 KER20545.1 - 0.029 14.5 0.1 0.086 13.0 0.1 1.8 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor UNC45-central PF11701.8 KER20545.1 - 0.11 12.4 0.2 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DIT1_PvcA PF05141.12 KER20545.1 - 0.5 9.8 4.5 1.2 8.6 1.4 2.3 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DctQ PF04290.12 KER20547.1 - 0.012 15.5 1.4 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Suf PF05843.14 KER20547.1 - 0.028 14.4 0.0 6.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) rve PF00665.26 KER20548.1 - 5.8e-07 29.7 0.0 2.2e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain Ion_trans PF00520.31 KER20549.1 - 5.1e-44 150.3 6.3 6.9e-44 149.9 6.3 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER20549.1 - 1.3e-22 79.9 0.0 4.1e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER20549.1 - 1.3e-12 47.5 4.3 1.3e-12 47.5 4.3 2.4 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KER20549.1 - 0.0015 17.3 2.8 0.0015 17.3 2.8 2.5 2 1 1 3 3 3 1 Polycystin cation channel BTB_3 PF16017.5 KER20549.1 - 0.03 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF2207 PF09972.9 KER20549.1 - 0.45 9.2 2.4 1.1 7.9 0.5 2.4 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) PDEase_I PF00233.19 KER20551.1 - 5.6e-75 252.1 0.9 9e-75 251.5 0.9 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KER20551.1 - 4.1e-21 76.0 0.0 2.1e-10 41.3 0.0 3.0 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KER20551.1 - 0.0022 18.4 0.0 4.7 7.6 0.0 4.2 3 1 0 3 3 3 1 GAF domain zinc_ribbon_2 PF13240.6 KER20551.1 - 0.26 11.1 1.1 0.52 10.1 1.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain GPR_Gpa2_C PF11970.8 KER20553.1 - 0.32 11.1 4.3 5.7 7.1 0.8 3.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Orthoreo_P10 PF07204.11 KER20553.1 - 4.5 7.3 6.8 3.2 7.8 0.0 3.5 3 1 1 4 4 4 0 Orthoreovirus membrane fusion protein p10 Ras PF00071.22 KER20555.1 - 1.3e-15 57.4 0.0 2.9e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KER20555.1 - 0.036 13.6 0.2 0.11 12.0 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PAP2 PF01569.21 KER20556.1 - 7.4e-25 87.3 2.7 7.4e-25 87.3 2.7 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KER20556.1 - 0.052 13.2 17.4 0.085 12.5 13.5 2.6 2 1 0 2 2 2 0 PAP2 superfamily DUF4713 PF15831.5 KER20556.1 - 2 8.9 0.0 2 8.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4713) Aminotran_1_2 PF00155.21 KER20558.1 - 6.6e-34 117.7 0.0 7.5e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UQ_con PF00179.26 KER20560.1 - 2.9e-23 82.1 0.0 5.9e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KER20560.1 - 0.015 15.1 0.3 0.052 13.4 0.3 1.9 1 1 0 1 1 1 0 UEV domain DUF4537 PF15057.6 KER20560.1 - 0.071 13.1 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 KER20560.1 - 0.12 12.2 0.0 5.1 7.0 0.0 3.1 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain Arc_C PF18162.1 KER20560.1 - 0.15 11.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Arc C-lobe LIM PF00412.22 KER20563.1 - 8.6e-61 202.0 87.1 5.2e-13 49.0 6.1 6.5 7 0 0 7 7 7 6 LIM domain RVT_1 PF00078.27 KER20563.1 - 2.7e-09 36.9 0.1 4.6e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PET PF06297.14 KER20563.1 - 0.00023 21.4 0.1 0.0037 17.5 0.1 2.4 1 1 0 1 1 1 1 PET Domain DUF5310 PF17237.2 KER20565.1 - 0.065 13.1 0.5 0.16 11.9 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5310) CD20 PF04103.15 KER20566.1 - 0.00021 21.4 21.8 0.00021 21.4 21.8 2.9 2 1 0 2 2 2 1 CD20-like family AAA PF00004.29 KER20567.1 - 1.5e-34 119.2 0.0 2.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER20567.1 - 5.3e-10 38.9 0.1 9.7e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KER20567.1 - 1.3e-05 25.4 0.1 0.0016 18.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KER20567.1 - 3.7e-05 24.2 0.0 0.00031 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KER20567.1 - 4.6e-05 23.4 0.1 0.00028 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KER20567.1 - 0.00038 19.9 0.0 0.51 9.7 0.0 2.7 2 1 1 3 3 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 KER20567.1 - 0.00041 20.1 0.0 0.0011 18.7 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KER20567.1 - 0.00075 19.1 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KER20567.1 - 0.00088 19.4 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KER20567.1 - 0.0014 18.1 0.2 0.0043 16.5 0.2 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KER20567.1 - 0.0019 18.0 0.0 0.0089 15.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KER20567.1 - 0.0039 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KER20567.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KER20567.1 - 0.0049 16.1 0.0 0.0081 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KER20567.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KER20567.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KER20567.1 - 0.012 15.5 0.1 0.045 13.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_2 PF07724.14 KER20567.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KER20567.1 - 0.015 14.9 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KER20567.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KER20567.1 - 0.032 14.8 0.0 0.069 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 KER20567.1 - 0.037 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KER20567.1 - 0.045 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KER20567.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KER20567.1 - 0.056 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KER20567.1 - 0.081 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KER20567.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KER20567.1 - 0.091 12.7 0.0 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KER20567.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 KER20567.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KER20567.1 - 0.16 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cullin_Nedd8 PF10557.9 KER20568.1 - 0.07 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain MRP-S26 PF14943.6 KER20571.1 - 8.2e-32 110.4 1.5 9.9e-32 110.2 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF1186 PF06685.11 KER20571.1 - 0.027 13.9 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) DUF1266 PF06889.11 KER20571.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Tubulin PF00091.25 KER20572.1 - 1.6e-66 224.3 0.0 2.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER20572.1 - 2.9e-49 166.4 0.1 5.1e-49 165.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER20572.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Ank_2 PF12796.7 KER20574.1 - 7.7e-72 237.9 17.5 2.1e-16 60.3 3.9 9.6 2 2 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER20574.1 - 3.1e-70 231.7 28.7 9e-13 48.5 0.1 13.1 6 3 6 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER20574.1 - 3.8e-58 186.6 26.1 0.00041 20.6 0.0 15.4 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 KER20574.1 - 2.2e-56 187.2 31.2 5.8e-06 26.5 0.1 13.1 7 2 6 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 KER20574.1 - 2e-51 170.3 39.4 2.9e-05 24.3 0.1 15.1 16 0 0 16 16 16 11 Ankyrin repeat AnkUBD PF18418.1 KER20574.1 - 0.004 17.3 0.2 9 6.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin ubiquitin-binding domain Nuc_H_symport PF03825.16 KER20574.1 - 0.054 12.5 0.1 0.076 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoside H+ symporter Sacchrp_dh_NADP PF03435.18 KER20574.1 - 0.065 13.5 0.0 0.61 10.3 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ion_trans PF00520.31 KER20575.1 - 2.5e-08 33.5 1.3 3.4e-08 33.0 1.3 1.3 1 0 0 1 1 1 1 Ion transport protein Zn_peptidase_2 PF04298.12 KER20575.1 - 0.093 12.1 0.5 0.17 11.3 0.5 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF5639 PF18690.1 KER20575.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) SRR1 PF07985.12 KER20576.1 - 7.7e-11 41.9 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 SRR1 Thiolase_N PF00108.23 KER20577.1 - 2.5e-71 240.1 0.5 4.9e-71 239.1 0.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KER20577.1 - 5.5e-40 135.8 0.0 1.3e-39 134.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KER20577.1 - 0.00011 21.9 3.3 0.00032 20.4 0.6 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain COX16 PF14138.6 KER20580.1 - 0.002 18.6 1.5 0.003 18.0 1.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 FUSC_2 PF13515.6 KER20580.1 - 0.044 13.9 0.2 0.058 13.5 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein-like HMG_box PF00505.19 KER20581.1 - 1.7e-09 37.9 1.4 2.4e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER20581.1 - 1.3e-07 32.1 0.1 3.5e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain UNC-79 PF14776.6 KER20581.1 - 0.0092 14.8 0.3 0.012 14.4 0.3 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 MlaC PF05494.12 KER20581.1 - 0.014 15.1 1.3 0.15 11.8 0.1 2.4 2 0 0 2 2 2 0 MlaC protein PIN_8 PF18476.1 KER20581.1 - 0.076 12.9 8.9 0.019 14.9 3.9 2.0 1 1 1 2 2 2 0 PIN like domain CNOT11 PF10155.9 KER20581.1 - 0.091 12.9 2.0 0.16 12.1 0.3 2.1 1 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 CENP-H PF05837.12 KER20581.1 - 0.46 10.9 9.8 0.064 13.7 3.3 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) IL11 PF07400.11 KER20581.1 - 0.59 9.8 10.5 0.82 9.3 2.5 2.8 2 1 1 3 3 3 0 Interleukin 11 APG6_N PF17675.1 KER20581.1 - 6.8 7.2 19.5 8.4 6.9 16.9 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF5535 PF17687.1 KER20582.1 - 0.085 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF2428 PF10350.9 KER20584.1 - 1.8e-09 37.3 3.8 2.4e-09 36.9 0.2 2.9 2 1 1 3 3 3 2 Putative death-receptor fusion protein (DUF2428) DUF5542 PF17696.1 KER20588.1 - 4.3 7.5 5.3 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Noelin-1 PF12308.8 KER20591.1 - 0.069 13.1 0.2 14 5.8 0.0 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein Mto2_bdg PF12808.7 KER20591.1 - 0.42 10.9 2.8 11 6.4 0.4 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PRIMA1 PF16101.5 KER20591.1 - 4.5 7.3 8.3 0.25 11.4 1.8 2.1 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 DUF2569 PF10754.9 KER20592.1 - 0.04 14.4 0.0 0.049 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Ig_3 PF13927.6 KER20593.1 - 0.023 15.3 0.0 0.59 10.8 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KER20593.1 - 0.027 14.6 0.1 5.7 7.2 0.0 3.0 2 1 0 2 2 2 0 Immunoglobulin V-set domain Pkinase PF00069.25 KER20599.1 - 4.7e-46 157.3 0.3 1.1e-45 156.1 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20599.1 - 2.8e-31 108.8 0.1 5e-31 107.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER20599.1 - 6.3e-05 22.4 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER20599.1 - 0.0021 16.9 0.0 0.0021 16.9 0.0 2.8 3 1 0 3 3 3 1 Fungal protein kinase DNA_pol_B PF00136.21 KER20600.1 - 1.2e-145 485.8 0.0 1.5e-145 485.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KER20600.1 - 9e-77 258.5 0.0 1.5e-76 257.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KER20600.1 - 1.1e-18 67.4 5.8 2.8e-18 66.2 5.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KER20600.1 - 0.0016 17.4 0.6 0.0029 16.5 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KER20600.1 - 0.0041 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 KER20600.1 - 3.7 7.5 5.0 23 4.9 5.0 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAO PF01266.24 KER20602.1 - 1e-60 206.2 0.0 1.3e-60 205.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KER20602.1 - 8.3e-05 22.8 0.2 0.00018 21.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KER20602.1 - 0.026 13.1 0.0 2.7 6.4 0.0 2.2 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 KER20602.1 - 0.033 13.3 0.0 0.59 9.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KER20602.1 - 0.045 13.0 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KER20602.1 - 0.081 12.2 0.1 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KER20602.1 - 0.099 12.6 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DASH_Spc34 PF08657.10 KER20603.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Ras PF00071.22 KER20604.1 - 3e-52 176.5 0.0 3.5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER20604.1 - 2.5e-30 105.2 0.0 4.6e-30 104.3 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER20604.1 - 4.1e-08 32.9 0.0 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER20604.1 - 3.7e-06 26.9 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KER20604.1 - 4.2e-06 26.3 0.0 5.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER20604.1 - 2.8e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KER20604.1 - 0.0015 18.9 0.0 0.0077 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER20604.1 - 0.0059 16.9 0.0 0.0098 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KER20604.1 - 0.0084 15.7 0.0 0.05 13.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KER20604.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KER20604.1 - 0.018 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER20604.1 - 0.05 14.1 0.1 0.16 12.5 0.1 2.0 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KER20604.1 - 0.051 12.7 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 KER20604.1 - 0.057 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KER20604.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.19 KER20604.1 - 0.13 11.9 0.0 9.7 5.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 KER20605.1 - 1.9e-15 56.9 12.9 6.4e-05 23.7 0.4 8.4 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20605.1 - 0.0016 18.7 0.2 1.4 9.2 0.0 5.0 6 1 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain E2R135 PF11570.8 KER20605.1 - 0.0057 16.9 6.0 0.0057 16.9 6.0 2.4 2 0 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 WD40_like PF17005.5 KER20605.1 - 0.0058 16.0 0.1 0.52 9.6 0.0 3.4 3 0 0 3 3 3 1 WD40-like domain Cytotoxic PF09000.10 KER20605.1 - 0.14 12.5 1.5 2.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Cytotoxic FoP_duplication PF13865.6 KER20606.1 - 0.088 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ABC_tran_CTD PF16326.5 KER20606.1 - 0.098 12.9 2.3 1 9.6 0.1 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain FapA PF03961.13 KER20606.1 - 0.29 9.7 0.8 0.36 9.4 0.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KER20606.1 - 2 7.9 5.6 3 7.3 5.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit adh_short_C2 PF13561.6 KER20608.1 - 1.2e-08 34.8 0.2 0.0012 18.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER20608.1 - 9.2e-08 31.8 0.1 0.003 17.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase HTH_IclR PF09339.10 KER20608.1 - 0.0039 17.0 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 2 IclR helix-turn-helix domain Epimerase PF01370.21 KER20608.1 - 0.032 13.7 0.0 8.1 5.8 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Imm58 PF15581.6 KER20608.1 - 0.037 14.1 0.0 1 9.5 0.0 2.2 1 1 1 2 2 2 0 Immunity protein 58 Phage_tail_X PF05489.12 KER20608.1 - 0.069 12.8 0.4 13 5.6 0.1 2.2 2 0 0 2 2 2 0 Phage Tail Protein X Forkhead PF00250.18 KER20610.1 - 3.8e-31 107.2 0.1 1.2e-30 105.6 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain TMEM219 PF14940.6 KER20612.1 - 4e-60 203.3 0.0 6.1e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Transmembrane 219 WD40 PF00400.32 KER20612.1 - 1.7e-38 129.9 7.8 8.1e-06 26.5 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KER20612.1 - 5.7e-14 51.4 0.9 1.2e-13 50.3 0.9 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KER20612.1 - 2.1e-09 37.5 0.0 0.1 12.9 0.0 6.3 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER20612.1 - 1.9e-06 26.9 0.5 0.43 9.1 0.0 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KER20612.1 - 3.5e-06 26.2 0.0 0.7 8.8 0.0 4.7 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KER20612.1 - 0.069 12.5 0.1 2.6 7.3 0.0 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal S4 PF01479.25 KER20612.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 S4 domain EF-hand_7 PF13499.6 KER20613.1 - 4e-11 43.2 0.0 4.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER20613.1 - 8e-11 40.7 0.1 2.9e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER20613.1 - 3.9e-10 38.8 0.1 0.00055 19.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KER20613.1 - 5.5e-09 35.1 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER20613.1 - 1.1e-08 34.7 0.0 0.00023 20.9 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KER20613.1 - 5.3e-05 23.1 0.0 5.7e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER20613.1 - 0.00079 19.7 0.0 0.00092 19.5 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Baculo_DNA_bind PF04786.12 KER20613.1 - 0.057 12.8 0.0 0.062 12.7 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein PriCT_1 PF08708.11 KER20613.1 - 0.062 13.1 0.3 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) EF-hand_9 PF14658.6 KER20613.1 - 0.16 12.3 0.0 0.56 10.6 0.0 1.7 1 1 1 2 2 2 0 EF-hand domain Glyco_hydro_15 PF00723.21 KER20614.1 - 2.6e-65 221.0 0.0 3.2e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 EF-hand_1 PF00036.32 KER20615.1 - 1.5e-19 68.0 2.5 3.2e-05 23.1 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KER20615.1 - 3.8e-19 68.9 0.4 4.8e-12 46.1 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER20615.1 - 1.5e-17 61.9 1.8 7.4e-05 22.4 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KER20615.1 - 8.3e-16 56.7 4.5 7.4e-05 22.1 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KER20615.1 - 8.2e-12 44.8 2.9 0.00012 21.9 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KER20615.1 - 0.00068 19.6 0.9 5.1 7.1 0.0 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER20615.1 - 0.0012 19.1 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 KER20615.1 - 0.017 15.5 0.0 0.84 10.1 0.0 2.5 2 1 1 3 3 3 0 Toprim-like Caleosin PF05042.13 KER20615.1 - 0.078 12.9 0.1 13 5.6 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein EF-hand_6 PF13405.6 KER20616.1 - 3e-16 57.9 0.7 1.7e-05 24.4 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KER20616.1 - 6.8e-16 56.6 1.1 0.0002 20.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KER20616.1 - 1.3e-13 51.2 0.3 1.8e-09 37.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER20616.1 - 4e-09 35.6 2.1 0.04 13.4 0.0 3.4 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KER20616.1 - 6.7e-09 35.5 1.1 0.00013 21.8 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER20616.1 - 1e-05 25.8 0.1 0.00017 21.9 0.1 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER20616.1 - 1.7e-05 24.6 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KER20616.1 - 0.0027 18.0 0.1 0.011 16.1 0.0 2.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KER20616.1 - 0.012 15.5 0.8 1.4 8.9 0.2 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TH1 PF04858.13 KER20616.1 - 0.018 13.7 0.0 0.021 13.5 0.0 1.0 1 0 0 1 1 1 0 TH1 protein TniB PF05621.11 KER20616.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein EF-hand_1 PF00036.32 KER20617.1 - 2.1e-07 30.0 0.1 2.8e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER20617.1 - 3.2e-07 29.7 0.3 4.5e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KER20617.1 - 3.7e-07 29.3 0.2 5.5e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KER20617.1 - 9e-05 22.8 0.0 0.0001 22.7 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER20617.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KER20618.1 - 7.9e-32 106.4 12.5 2.1e-06 26.9 0.5 5.2 5 0 0 5 5 5 5 EF hand EF-hand_5 PF13202.6 KER20618.1 - 6.2e-31 104.5 8.4 2.2e-06 26.9 0.1 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KER20618.1 - 4.4e-28 94.8 12.0 2.2e-06 27.1 1.5 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KER20618.1 - 4.4e-25 87.9 12.2 1.6e-10 41.3 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KER20618.1 - 7.1e-14 51.4 8.8 0.021 14.7 0.5 5.3 5 0 0 5 5 5 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER20618.1 - 8.3e-09 35.8 4.0 0.0069 16.7 0.0 3.1 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KER20618.1 - 3.7e-06 27.0 0.0 2.8 8.2 0.0 4.2 4 0 0 4 4 4 2 Dockerin type I domain Caleosin PF05042.13 KER20618.1 - 0.0016 18.4 1.7 0.052 13.5 0.7 3.7 2 1 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.7 KER20618.1 - 0.0018 18.2 7.7 0.63 10.0 0.5 3.6 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KER20618.1 - 0.0057 17.5 0.0 1.3 9.9 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 KER20618.1 - 0.017 15.5 0.1 0.23 11.8 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain PheRS_DBD3 PF18553.1 KER20618.1 - 0.028 14.7 2.0 9.2 6.6 0.0 3.6 3 1 1 4 4 4 0 PheRS DNA binding domain 3 NADPH_Ox PF08414.10 KER20618.1 - 0.031 14.6 0.1 0.2 12.0 0.0 2.2 2 1 1 3 3 3 0 Respiratory burst NADPH oxidase EF-hand_10 PF14788.6 KER20618.1 - 0.077 12.9 5.4 54 3.8 0.0 4.6 4 1 1 5 5 5 0 EF hand EF-hand_14 PF17959.1 KER20618.1 - 0.092 13.1 3.3 2.2 8.7 1.8 3.0 2 1 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 KER20619.1 - 0.00072 18.9 0.1 0.00072 18.9 0.1 1.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KER20619.1 - 0.001 18.5 0.1 0.001 18.5 0.1 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER20619.1 - 0.0039 17.0 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KER20619.1 - 0.038 14.4 0.1 0.062 13.8 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KER20619.1 - 0.048 13.5 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KER20620.1 - 1.3e-25 86.9 15.6 2.9e-05 23.3 0.1 6.2 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 KER20620.1 - 5.4e-25 87.6 9.2 1e-09 38.7 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KER20620.1 - 2.7e-21 74.1 12.3 0.00065 19.1 0.1 6.7 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 KER20620.1 - 2.5e-20 72.1 14.9 1.1e-09 38.0 0.5 5.3 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 KER20620.1 - 1.2e-19 68.5 14.1 0.00097 18.9 0.1 6.2 6 0 0 6 6 6 6 EF-hand domain SPARC_Ca_bdg PF10591.9 KER20620.1 - 3.7e-11 43.3 4.3 0.00056 20.2 0.3 3.1 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER20620.1 - 0.002 18.1 4.4 9.9 6.2 0.3 4.0 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand DUF2789 PF10982.8 KER20620.1 - 0.061 13.5 1.2 0.2 11.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) YflT PF11181.8 KER20620.1 - 0.11 13.0 0.2 10 6.7 0.1 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT DUF2141 PF09912.9 KER20620.1 - 0.18 11.7 0.7 24 4.9 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) zf-LITAF-like PF10601.9 KER20621.1 - 2.5e-24 85.3 9.4 1.2e-23 83.1 8.6 2.0 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain DUF1610 PF07754.11 KER20621.1 - 0.029 14.3 0.7 0.029 14.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Prok-RING_4 PF14447.6 KER20621.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KER20621.1 - 1 9.3 10.8 0.65 9.9 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KER20622.1 - 2.3e-54 184.5 0.0 1.8e-28 99.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER20622.1 - 2e-29 102.7 0.0 1.7e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER20622.1 - 0.0031 16.9 0.0 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PrmA PF06325.13 KER20623.1 - 4.4e-05 23.0 0.2 7.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KER20623.1 - 0.0048 17.6 0.2 0.036 14.8 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KER20623.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KER20623.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KER20623.1 - 0.12 12.1 0.1 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Lysine methyltransferase Zip PF02535.22 KER20624.1 - 6.6e-40 137.3 9.8 2.6e-39 135.4 9.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter LRR_4 PF12799.7 KER20625.1 - 1.9e-10 40.8 7.2 1.3e-07 31.8 1.9 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER20625.1 - 9.2e-07 28.5 5.9 0.00029 20.5 2.4 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KER20625.1 - 0.00073 19.8 9.4 0.38 11.5 0.1 3.9 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 KER20625.1 - 0.011 15.3 0.2 0.013 15.0 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat STAT1_TAZ2bind PF12162.8 KER20625.1 - 0.057 13.0 1.1 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain RsmF_methylt_CI PF17126.5 KER20625.1 - 0.096 12.7 0.1 0.78 9.8 0.0 2.5 1 1 2 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain DSPc PF00782.20 KER20626.1 - 8.5e-35 119.5 0.0 1.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KER20626.1 - 2.3e-06 28.1 0.0 1.8e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KER20626.1 - 0.00031 20.4 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KER20626.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DEAD PF00270.29 KER20627.1 - 7.1e-37 126.9 0.0 1.2e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER20627.1 - 1.1e-27 96.5 0.0 3e-26 92.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KER20627.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KER20627.1 - 0.013 15.8 0.6 0.057 13.7 0.6 2.0 1 1 0 1 1 1 0 AAA domain DUF3738 PF12543.8 KER20629.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) RVP PF00077.20 KER20630.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease E1_DerP2_DerF2 PF02221.15 KER20631.1 - 1e-09 38.9 0.1 1.3e-09 38.6 0.1 1.1 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KER20632.1 - 9.8e-09 35.7 0.4 2.2e-07 31.4 0.4 2.5 1 1 0 1 1 1 1 ML domain UQ_con PF00179.26 KER20633.1 - 1e-25 90.0 0.0 1.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Frizzled PF01534.17 KER20634.1 - 5.9e-21 74.9 19.0 4.2e-16 58.9 5.7 3.5 3 1 1 4 4 4 2 Frizzled/Smoothened family membrane region Fz PF01392.22 KER20634.1 - 1.4e-07 32.1 0.0 1e-06 29.3 0.0 2.6 1 1 0 1 1 1 1 Fz domain Mid1 PF12929.7 KER20634.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component GST_N_3 PF13417.6 KER20637.1 - 3.3e-13 49.8 0.0 5.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER20637.1 - 7.2e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KER20637.1 - 2e-10 40.8 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KER20637.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KER20637.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER20637.1 - 0.0015 18.7 0.0 0.0069 16.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KER20637.1 - 0.022 15.4 0.0 0.032 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KER20637.1 - 0.029 15.1 0.0 0.46 11.2 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KER20637.1 - 0.052 13.8 0.0 0.25 11.6 0.0 2.1 3 0 0 3 3 3 0 Glutaredoxin DHC_N2 PF08393.13 KER20638.1 - 1e-60 206.0 0.0 1.6e-38 132.9 0.0 2.1 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KER20638.1 - 1.3e-24 86.8 0.8 2.1e-24 86.1 0.6 1.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Tetraspanin PF00335.20 KER20639.1 - 6e-07 29.4 0.8 6.8e-07 29.2 0.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 KER20640.1 - 6.9e-12 45.6 0.5 9.1e-12 45.2 0.5 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2157 PF09925.9 KER20640.1 - 0.033 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Tetraspanin PF00335.20 KER20641.1 - 2.2e-05 24.3 9.6 4.4e-05 23.3 1.1 2.0 1 1 1 2 2 2 2 Tetraspanin family TMEM43 PF07787.12 KER20641.1 - 0.21 10.9 0.2 0.36 10.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Tetraspanin PF00335.20 KER20642.1 - 3.4e-08 33.5 0.4 4.2e-08 33.2 0.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Cse1 PF08506.10 KER20643.1 - 4.5e-114 381.1 0.0 1.1e-111 373.2 0.0 2.4 1 1 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KER20643.1 - 2.6e-76 256.9 1.0 4.4e-42 144.1 1.2 2.8 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus RVT_1 PF00078.27 KER20643.1 - 1.4e-17 63.9 0.0 2.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Xpo1 PF08389.12 KER20643.1 - 0.014 15.5 0.1 0.21 11.6 0.0 2.9 2 1 0 2 2 2 0 Exportin 1-like protein DUF3437 PF11919.8 KER20643.1 - 0.065 13.2 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) GST_N_2 PF13409.6 KER20643.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Asp PF00026.23 KER20644.1 - 3.8e-10 39.7 0.0 4.5e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SET PF00856.28 KER20645.1 - 1.5e-15 58.0 0.3 1.5e-15 58.0 0.3 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KER20645.1 - 3.1e-10 40.7 9.1 3.1e-10 40.7 9.1 2.5 3 0 0 3 3 3 1 Pre-SET motif AWS PF17907.1 KER20645.1 - 0.029 14.4 3.1 0.029 14.4 3.1 3.4 3 0 0 3 3 3 0 AWS domain bZIP_1 PF00170.21 KER20647.1 - 0.019 15.0 1.8 0.019 15.0 1.8 4.9 5 0 0 5 5 5 0 bZIP transcription factor YgaB PF14182.6 KER20647.1 - 0.022 15.1 3.5 0.022 15.1 3.5 3.6 1 1 2 3 3 3 0 YgaB-like protein Spc7 PF08317.11 KER20647.1 - 0.053 12.4 33.0 0.011 14.7 14.4 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KER20647.1 - 0.064 13.7 8.6 4.1 7.9 0.1 3.5 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 KER20647.1 - 0.13 11.7 33.1 1.4 8.3 16.2 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KER20647.1 - 0.32 8.5 25.4 0.48 7.9 25.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KER20647.1 - 0.36 10.9 9.2 3.6 7.6 1.8 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 KER20647.1 - 0.86 8.9 29.6 0.3 10.4 5.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 KER20647.1 - 0.98 10.0 21.8 0.66 10.6 6.9 3.0 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF4363 PF14276.6 KER20647.1 - 1.2 9.3 9.7 1.6 8.9 0.3 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4363) ATG16 PF08614.11 KER20647.1 - 1.6 8.9 37.3 1.7 8.9 19.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KER20647.1 - 1.9 8.5 14.9 1 9.4 3.4 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) GAS PF13851.6 KER20647.1 - 2 7.7 31.4 0.2 11.0 8.8 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding RPW8 PF05659.11 KER20647.1 - 2.4 7.8 8.3 0.96 9.1 0.4 3.0 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Jnk-SapK_ap_N PF09744.9 KER20647.1 - 2.9 8.1 37.2 0.93 9.7 9.0 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 KER20647.1 - 3.3 8.1 18.4 6.3 7.2 4.5 3.5 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 KER20647.1 - 3.4 7.7 26.0 0.14 12.2 4.9 4.4 4 1 0 4 4 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 KER20647.1 - 4.9 7.2 18.0 1.5 8.8 7.1 2.8 1 1 2 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KER20647.1 - 5.3 7.1 32.6 3.6 7.7 10.4 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KER20647.1 - 6.1 7.2 34.4 0.089 13.2 16.1 2.7 1 1 2 3 3 3 0 Fez1 MobC PF05713.11 KER20647.1 - 6.4 7.3 6.2 1.2e+02 3.2 0.1 3.8 3 1 0 3 3 3 0 Bacterial mobilisation protein (MobC) TMPIT PF07851.13 KER20647.1 - 7.4 5.7 18.6 0.18 11.1 5.4 2.3 1 1 1 2 2 2 0 TMPIT-like protein DUF2381 PF09544.10 KER20647.1 - 9.4 5.7 17.9 6.1 6.3 5.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2381) EF-hand_1 PF00036.32 KER20648.1 - 7.7e-33 109.6 17.2 1.4e-06 27.4 0.7 8.6 8 0 0 8 8 8 8 EF hand EF-hand_6 PF13405.6 KER20648.1 - 1.6e-25 86.8 20.5 2.2e-05 24.0 0.6 8.6 8 0 0 8 8 8 6 EF-hand domain EF-hand_5 PF13202.6 KER20648.1 - 4.2e-23 79.8 23.8 0.0017 17.8 0.1 8.5 8 0 0 8 8 8 6 EF hand EF-hand_7 PF13499.6 KER20648.1 - 7.2e-20 71.2 24.2 1.5e-08 34.9 2.1 5.9 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.6 KER20648.1 - 1.2e-10 41.1 23.4 0.015 15.2 0.2 7.8 7 2 2 9 9 9 5 EF-hand domain pair EF-hand_10 PF14788.6 KER20648.1 - 7.6e-05 22.5 5.9 2.9 7.8 0.1 5.2 5 0 0 5 5 5 2 EF hand RII_binding_1 PF10522.9 KER20648.1 - 0.016 15.3 0.0 13 6.3 0.0 2.7 2 0 0 2 2 2 0 RII binding domain Put_Phosphatase PF06888.12 KER20648.1 - 0.018 14.5 0.1 0.042 13.2 0.1 1.6 1 1 0 1 1 1 0 Putative Phosphatase DUF3579 PF12112.8 KER20648.1 - 0.022 15.3 0.1 7.2 7.2 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3579) DUF3775 PF12616.8 KER20648.1 - 0.023 14.7 0.4 8.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) Dockerin_1 PF00404.18 KER20648.1 - 0.026 14.7 9.3 1.3 9.2 0.1 4.5 5 0 0 5 5 4 0 Dockerin type I domain AbiJ_NTD5 PF18865.1 KER20648.1 - 2.3 8.1 8.0 0.29 11.0 1.8 2.6 3 1 1 4 4 4 0 AbiJ N-terminal domain 5 DUF1722 PF08349.11 KER20649.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Ceramidse_alk_C PF17048.5 KER20650.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal SRF-TF PF00319.18 KER20652.1 - 2.9e-20 71.5 0.2 5.5e-20 70.6 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cadherin PF00028.17 KER20655.1 - 6.1e-84 276.6 0.4 1e-18 67.5 0.0 10.3 8 3 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.12 KER20655.1 - 1.6e-12 47.0 0.3 1e-05 25.3 0.0 5.7 5 1 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 KER20655.1 - 8.4e-10 38.6 4.0 0.0034 17.4 0.0 5.9 6 0 0 6 6 6 3 Cadherin-like Cadherin_4 PF17803.1 KER20655.1 - 0.014 16.0 0.1 0.014 16.0 0.1 3.9 5 0 0 5 5 5 0 Bacterial cadherin-like domain Ion_trans PF00520.31 KER20656.1 - 3.5e-38 131.2 19.1 1.3e-37 129.3 19.1 1.8 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER20656.1 - 7.4e-29 100.0 0.0 2.5e-28 98.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER20656.1 - 1.1e-10 41.3 3.9 1.1e-10 41.3 3.9 1.9 2 0 0 2 2 2 1 Ion channel Wzy_C PF04932.15 KER20656.1 - 0.015 14.9 0.2 0.86 9.2 0.1 2.6 2 1 0 2 2 2 0 O-Antigen ligase DUF3185 PF11381.8 KER20656.1 - 0.13 12.3 2.8 0.29 11.2 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PKD_channel PF08016.12 KER20656.1 - 1.4 7.5 6.9 0.19 10.4 2.2 1.8 2 0 0 2 2 2 0 Polycystin cation channel TPR_12 PF13424.6 KER20657.1 - 2.5e-07 30.9 10.3 0.00052 20.3 0.5 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER20657.1 - 0.0023 17.7 6.6 0.18 11.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER20657.1 - 0.0038 17.1 0.4 0.93 9.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER20657.1 - 0.0082 16.1 4.9 2.2 8.5 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KER20657.1 - 0.012 15.7 4.3 0.63 10.2 0.8 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KER20657.1 - 0.058 13.5 14.3 0.96 9.7 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER20657.1 - 3.7 8.0 13.8 1.8 9.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RVT_1 PF00078.27 KER20660.1 - 0.0063 16.1 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KER20661.1 - 1.4e-08 34.5 0.0 2.1e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 KER20662.1 - 1.6e-13 51.0 7.4 0.00028 21.4 0.0 7.9 7 1 0 7 7 7 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER20662.1 - 1.7e-07 31.4 5.4 0.015 15.6 0.0 6.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER20662.1 - 2.9e-07 30.9 5.9 1.1 9.9 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KER20662.1 - 0.00026 21.3 3.3 46 4.7 0.0 6.7 6 0 0 6 6 6 0 Ankyrin repeat Ank_3 PF13606.6 KER20662.1 - 0.00028 21.1 13.6 21 6.1 0.1 9.9 11 0 0 11 11 11 1 Ankyrin repeat UCH PF00443.29 KER20665.1 - 2.2e-40 138.8 0.0 1.4e-39 136.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER20665.1 - 1.2e-28 100.6 0.5 3.9e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EcoEI_R_C PF08463.10 KER20665.1 - 0.21 11.7 2.0 0.22 11.6 0.4 1.9 2 0 0 2 2 2 0 EcoEI R protein C-terminal COQ7 PF03232.13 KER20671.1 - 5.6e-72 241.1 0.0 6.4e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4677 PF15726.5 KER20671.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) GHMP_kinases_C PF08544.13 KER20675.1 - 3.7e-14 52.9 0.0 8.2e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ntox34 PF15606.6 KER20675.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 34 zf-LSD1 PF06943.12 KER20676.1 - 0.69 9.8 3.1 0.42 10.5 0.3 2.1 2 0 0 2 2 2 0 LSD1 zinc finger PP2C PF00481.21 KER20677.1 - 7.5e-37 127.3 0.0 1.3e-35 123.2 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C GalKase_gal_bdg PF10509.9 KER20677.1 - 1.7e-20 72.3 0.1 3.3e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PP2C_2 PF13672.6 KER20677.1 - 1.4e-07 31.4 0.1 5.4e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C RNA_pol_Rpb2_45 PF10385.9 KER20677.1 - 0.057 13.7 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain G-alpha PF00503.20 KER20678.1 - 1.2e-72 245.0 5.0 2e-70 237.7 2.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KER20678.1 - 3.6e-14 52.6 0.4 9.8e-11 41.4 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER20678.1 - 0.0013 18.1 1.4 0.024 14.0 0.3 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER20678.1 - 0.0024 18.0 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 KER20678.1 - 0.015 15.2 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain GTP_EFTU PF00009.27 KER20678.1 - 0.016 14.8 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KER20678.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KER20678.1 - 0.076 12.8 0.1 0.22 11.3 0.1 1.8 1 1 0 1 1 1 0 P-loop containing region of AAA domain Proteasome PF00227.26 KER20679.1 - 3.1e-19 69.2 0.0 3.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Clathrin PF00637.20 KER20680.1 - 3.3e-201 659.2 35.9 1.2e-32 112.8 2.2 7.1 7 0 0 7 7 7 7 Region in Clathrin and VPS TPR_14 PF13428.6 KER20680.1 - 2.4e-07 31.0 7.2 4.6 8.3 0.1 8.3 8 1 1 9 9 9 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KER20680.1 - 4.4e-06 26.0 0.1 0.0029 16.7 0.0 2.5 2 0 0 2 2 2 2 Coatomer WD associated region TPR_2 PF07719.17 KER20680.1 - 0.0001 22.1 3.1 2 8.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER20680.1 - 0.00052 19.8 11.1 10 6.4 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER20680.1 - 0.0054 16.5 5.3 5.5 7.0 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER20680.1 - 0.05 13.8 6.3 33 5.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER20680.1 - 0.13 12.5 6.0 37 4.7 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1869 PF08956.10 KER20680.1 - 0.15 12.0 0.3 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) TPR_10 PF13374.6 KER20680.1 - 0.17 11.8 4.8 3.5 7.6 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TSP_1 PF00090.19 KER20681.1 - 2.6e-09 37.2 6.6 2.6e-09 37.2 6.6 2.7 2 0 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 KER20681.1 - 0.0034 17.8 23.4 0.0034 17.8 23.4 3.2 3 1 0 3 3 3 1 Somatomedin B domain SEP PF08059.13 KER20682.1 - 1.7e-23 82.9 0.0 4.3e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KER20682.1 - 2.2e-17 63.0 0.1 1.1e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KER20682.1 - 5.7e-11 42.1 1.6 9.7e-11 41.3 1.6 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KER20682.1 - 0.16 11.7 0.1 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 TAP C-terminal domain MBOAT PF03062.19 KER20685.1 - 5.2e-08 32.6 4.5 8.7e-08 31.9 4.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-C2H2 PF00096.26 KER20685.1 - 0.00026 21.2 12.0 0.00032 21.0 1.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER20685.1 - 0.011 16.5 11.3 0.023 15.5 0.5 3.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KER20685.1 - 0.038 14.0 4.6 0.49 10.4 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KER20685.1 - 0.046 14.2 9.0 6.6 7.3 0.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain tRNA_int_endo PF01974.17 KER20685.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain zf-C2H2_11 PF16622.5 KER20685.1 - 0.14 11.9 2.8 0.14 11.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-DBF PF07535.12 KER20685.1 - 0.61 10.2 2.1 1.7 8.8 2.1 1.8 1 0 0 1 1 1 0 DBF zinc finger RVT_1 PF00078.27 KER20686.1 - 2.1e-16 60.1 0.0 6.8e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 KER20686.1 - 0.00017 20.7 16.9 0.012 14.6 13.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1270 PF06900.11 KER20686.1 - 2.8 8.4 8.9 2.8 8.4 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) LapA_dom PF06305.11 KER20686.1 - 3 7.7 5.2 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SDA1 PF05285.12 KER20687.1 - 0.081 12.3 16.0 0.081 12.3 16.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KER20687.1 - 0.35 9.0 13.9 0.35 9.0 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KER20687.1 - 5.7 6.2 13.1 5.8 6.2 13.1 1.1 1 0 0 1 1 1 0 BUD22 zf-C2H2_4 PF13894.6 KER20688.1 - 0.00054 20.6 6.1 0.54 11.2 0.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1924 PF09086.11 KER20688.1 - 0.097 13.0 0.1 4.8 7.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) zf-Di19 PF05605.12 KER20688.1 - 0.53 10.6 0.1 0.53 10.6 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3989 PF13150.6 KER20689.1 - 0.072 12.8 0.4 6.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Ras PF00071.22 KER20690.1 - 1.6e-48 164.3 0.1 2.2e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER20690.1 - 1.2e-17 64.2 0.0 4.5e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER20690.1 - 1.8e-09 37.3 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER20690.1 - 0.0018 17.7 0.1 0.0056 16.1 0.0 1.8 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KER20690.1 - 0.0023 17.9 1.5 0.47 10.3 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KER20690.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KER20690.1 - 0.0099 15.6 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 KER20690.1 - 0.018 14.6 0.3 0.1 12.2 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KER20690.1 - 0.031 14.6 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KER20690.1 - 0.058 13.5 0.5 4.2 7.4 0.0 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 KER20690.1 - 0.11 12.8 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Borrelia_P13 PF05628.12 KER20693.1 - 0.11 12.5 0.7 0.19 11.7 0.7 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 CEBP1_N PF16368.5 KER20693.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus VIT1 PF01988.19 KER20693.1 - 0.21 11.4 3.7 0.41 10.5 3.6 1.5 1 1 0 1 1 1 0 VIT family MFS_1 PF07690.16 KER20695.1 - 0.013 14.5 47.7 0.029 13.3 23.3 3.7 2 1 1 3 3 3 0 Major Facilitator Superfamily Filament PF00038.21 KER20699.1 - 0.0029 17.3 206.3 0.0098 15.5 39.7 8.5 1 1 7 8 8 8 7 Intermediate filament protein AP_endonuc_2 PF01261.24 KER20699.1 - 0.19 11.1 6.7 1.4 8.3 0.4 4.0 3 1 0 3 3 3 0 Xylose isomerase-like TIM barrel Pkinase PF00069.25 KER20700.1 - 1.5e-27 96.6 0.0 1.9e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20700.1 - 6.3e-14 51.9 0.0 7.4e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER20700.1 - 2.9e-08 32.9 0.0 3.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER20700.1 - 1.4e-07 31.7 0.0 0.00034 20.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KER20700.1 - 9.7e-05 21.8 0.2 0.00027 20.3 0.0 1.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Atg14 PF10186.9 KER20701.1 - 0.17 11.0 1.8 2.7 7.0 1.8 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KER20701.1 - 0.19 10.6 0.3 0.38 9.6 0.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein NAD_Gly3P_dh_N PF01210.23 KER20703.1 - 9.9e-49 165.3 0.0 1.5e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KER20703.1 - 3.6e-46 157.0 0.0 7e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KER20703.1 - 0.012 16.2 0.1 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 7tm_1 PF00001.21 KER20709.1 - 1.2e-06 28.1 0.0 1.2e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PcF PF09461.10 KER20710.1 - 0.048 14.0 0.1 6.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Phytotoxin PcF protein Amastin PF07344.11 KER20712.1 - 0.036 13.9 1.3 0.036 13.9 1.3 2.5 3 0 0 3 3 3 0 Amastin surface glycoprotein Tetraspanin PF00335.20 KER20712.1 - 0.082 12.6 4.6 1.4 8.6 0.3 2.7 3 0 0 3 3 3 0 Tetraspanin family Neurensin PF14927.6 KER20712.1 - 0.12 12.1 1.9 0.85 9.3 0.3 2.3 1 1 1 2 2 2 0 Neurensin TMEM171 PF15471.6 KER20712.1 - 0.6 9.0 2.6 7.6 5.4 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein family 171 Popeye PF04831.13 KER20712.1 - 3.2 7.9 5.0 4.9 7.3 0.3 2.3 2 0 0 2 2 2 0 Popeye protein conserved region Ribosomal_L1 PF00687.21 KER20713.1 - 4.8e-09 36.2 0.0 6.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HLH PF00010.26 KER20714.1 - 2.5e-11 43.3 5.9 4.3e-11 42.6 5.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PHD20L1_u1 PF16660.5 KER20714.1 - 0.048 14.4 1.9 0.071 13.8 0.6 2.0 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 DUF4959 PF16323.5 KER20715.1 - 0.023 15.0 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4959) Trypsin PF00089.26 KER20716.1 - 3.4e-18 66.3 0.0 7.1e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KER20716.1 - 4.7e-08 34.1 0.2 1.4e-07 32.5 0.2 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KER20716.1 - 0.055 12.7 0.5 0.086 12.0 0.5 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.15 KER20716.1 - 0.066 13.0 0.3 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease NUC153 PF08159.12 KER20717.1 - 0.009 15.8 0.8 0.02 14.7 0.8 1.6 1 0 0 1 1 1 1 NUC153 domain RRM_1 PF00076.22 KER20717.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3K_1B_p101 PF10486.9 KER20717.1 - 0.67 7.7 5.4 1.1 6.9 5.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GAS2 PF02187.17 KER20718.1 - 6.1e-29 99.9 1.1 1.7e-28 98.5 0.2 2.2 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KER20718.1 - 6.9e-12 45.5 0.1 3.3e-11 43.3 0.0 2.2 2 1 0 2 2 2 1 Calponin homology (CH) domain Fz PF01392.22 KER20719.1 - 2.8e-27 95.5 4.4 2.8e-27 95.5 4.4 2.1 2 0 0 2 2 2 1 Fz domain Raftlin PF15250.6 KER20719.1 - 0.0005 19.0 1.2 0.00078 18.3 1.2 1.2 1 0 0 1 1 1 1 Raftlin Abhydrolase_6 PF12697.7 KER20721.1 - 0.041 14.5 1.2 0.066 13.8 0.1 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Guanylate_kin PF00625.21 KER20723.1 - 4.1e-59 199.3 0.0 4.6e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.27 KER20723.1 - 2.3e-06 28.2 0.0 3.5e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KER20723.1 - 1.5e-05 25.3 0.1 4.4e-05 23.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KER20723.1 - 5.4e-05 23.4 0.0 0.0024 18.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KER20723.1 - 5.9e-05 23.1 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KER20723.1 - 9.3e-05 22.9 0.0 0.00041 20.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KER20723.1 - 0.0001 22.8 0.1 0.00019 22.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KER20723.1 - 0.00016 22.0 0.2 0.00093 19.6 0.1 2.4 2 1 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 KER20723.1 - 0.0005 20.1 0.0 0.00079 19.4 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KER20723.1 - 0.00086 18.9 0.0 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KER20723.1 - 0.00089 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KER20723.1 - 0.0016 18.9 0.0 0.0029 18.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KER20723.1 - 0.0017 18.9 1.2 0.0074 16.8 1.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KER20723.1 - 0.0042 17.1 0.0 0.0082 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KER20723.1 - 0.0077 16.3 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KER20723.1 - 0.023 14.4 0.2 0.086 12.6 0.1 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 KER20723.1 - 0.027 13.3 0.1 0.054 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 KER20723.1 - 0.03 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 KER20723.1 - 0.033 13.9 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 KER20723.1 - 0.034 14.1 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KER20723.1 - 0.035 13.4 0.0 0.066 12.5 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_15 PF13175.6 KER20723.1 - 0.038 13.7 0.2 0.65 9.6 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KER20723.1 - 0.04 14.2 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KER20723.1 - 0.045 12.9 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain dNK PF01712.19 KER20723.1 - 0.066 13.1 0.2 0.78 9.6 0.2 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase NACHT PF05729.12 KER20723.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 KER20723.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PRK PF00485.18 KER20723.1 - 0.094 12.4 0.1 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 KER20723.1 - 0.1 12.0 0.5 0.47 9.8 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MnmE_helical PF12631.7 KER20723.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 MnmE helical domain AAA_19 PF13245.6 KER20723.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KER20723.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain I-set PF07679.16 KER20724.1 - 2.3e-10 40.4 0.0 0.0037 17.3 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KER20724.1 - 2.3e-09 37.7 0.3 4.6e-05 23.9 0.0 4.1 3 2 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KER20724.1 - 7.3e-08 32.5 0.1 0.013 15.7 0.1 3.6 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KER20724.1 - 1.2e-07 32.0 0.5 0.00038 20.8 0.2 4.1 2 2 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KER20724.1 - 0.0003 20.3 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER20724.1 - 0.0076 16.4 0.1 0.92 9.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin V-set domain zf-MIZ PF02891.20 KER20726.1 - 0.029 14.1 0.2 0.039 13.7 0.2 1.2 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Homeodomain PF00046.29 KER20727.1 - 7.3e-12 45.0 0.1 1.4e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Glu_cys_ligase PF04262.14 KER20727.1 - 0.066 11.8 0.1 0.088 11.4 0.1 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Homeodomain PF00046.29 KER20728.1 - 0.00015 21.5 1.4 0.00034 20.4 1.4 1.6 1 0 0 1 1 1 1 Homeodomain TPR_1 PF00515.28 KER20730.1 - 9.6e-29 98.0 23.8 1.7e-07 30.8 0.3 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KER20730.1 - 6.1e-21 72.8 31.9 3.2e-05 23.7 0.2 10.8 12 1 1 13 13 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 KER20730.1 - 9.5e-17 60.4 14.8 0.00027 20.6 0.2 9.1 7 1 3 10 10 9 5 TPR repeat TPR_14 PF13428.6 KER20730.1 - 1.3e-11 44.3 23.6 0.07 14.0 0.0 9.8 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KER20730.1 - 1.7e-11 43.4 16.0 1.2 9.5 0.0 9.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KER20730.1 - 2.3e-10 40.5 16.2 0.16 12.1 0.2 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER20730.1 - 3.2e-08 34.1 20.1 0.16 12.6 0.5 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KER20730.1 - 3.6e-08 33.8 30.6 0.28 11.7 0.1 8.1 7 1 1 8 8 8 4 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER20730.1 - 4e-08 32.6 1.5 0.14 11.7 0.0 4.8 4 0 0 4 4 4 2 SHNi-TPR TPR_12 PF13424.6 KER20730.1 - 9e-08 32.3 21.1 0.041 14.2 0.0 8.7 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER20730.1 - 7.8e-07 29.1 19.9 1.4 9.5 0.1 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat MIT PF04212.18 KER20730.1 - 2e-05 24.6 10.6 0.13 12.4 0.1 5.1 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 KER20730.1 - 0.00053 19.3 7.6 0.73 9.0 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3195 PF11424.8 KER20730.1 - 0.0018 18.3 0.8 2.1 8.5 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3195) TPR_21 PF09976.9 KER20730.1 - 0.0051 16.6 0.9 0.0051 16.6 0.9 4.6 4 2 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KER20730.1 - 0.0084 16.1 11.8 2.6 8.3 0.0 6.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KER20730.1 - 0.012 16.2 0.5 22 6.1 0.0 4.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KER20730.1 - 0.014 15.0 2.7 1.1 8.9 0.2 3.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Bclx_interact PF08945.10 KER20730.1 - 0.18 11.6 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain TPR_6 PF13174.6 KER20730.1 - 0.91 10.3 17.5 1.3e+02 3.5 0.1 8.6 8 2 0 8 8 8 0 Tetratricopeptide repeat HemY_N PF07219.13 KER20730.1 - 1.2 9.4 10.3 5.8 7.2 0.1 4.9 5 0 0 5 5 5 0 HemY protein N-terminus RVT_1 PF00078.27 KER20731.1 - 6.1e-08 32.4 0.0 0.002 17.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_5 PF13909.6 KER20733.1 - 3.5 7.5 5.3 1 9.2 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain LRR_4 PF12799.7 KER20734.1 - 3.4e-15 55.9 12.7 3.5e-08 33.6 4.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER20734.1 - 2.4e-14 53.2 0.2 3.7e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KER20734.1 - 8.3e-09 35.1 9.5 1.4e-05 24.7 2.6 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 KER20734.1 - 0.1 12.7 9.5 0.96 9.7 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Na_trans_assoc PF06512.13 KER20734.1 - 2 8.6 8.7 5.9 7.1 0.8 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Radial_spoke PF04712.12 KER20734.1 - 2.5 6.9 6.9 2.8 6.8 0.7 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Mpp10 PF04006.12 KER20734.1 - 6.8 5.0 15.4 1.7 7.0 4.1 2.1 2 0 0 2 2 2 0 Mpp10 protein FAM176 PF14851.6 KER20734.1 - 7.1 6.3 12.0 0.87 9.2 0.1 2.5 2 0 0 2 2 2 0 FAM176 family C2 PF00168.30 KER20735.1 - 0.0022 18.3 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain tRNA_int_endo PF01974.17 KER20741.1 - 4.4e-11 42.7 0.4 1.2e-10 41.3 0.2 1.8 1 1 1 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain RTT107_BRCT_5 PF16770.5 KER20741.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain tRNA_int_endo PF01974.17 KER20742.1 - 2.5e-13 49.9 0.0 4.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KER20742.1 - 0.00024 20.7 0.0 0.00083 19.0 0.0 2.0 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Peptidase_C12 PF01088.21 KER20744.1 - 7.7e-57 192.4 0.0 1.2e-38 133.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 SPOC PF07744.13 KER20747.1 - 3e-35 121.4 0.0 6.5e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KER20747.1 - 2.8e-32 110.3 0.1 2.3e-11 43.3 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER20747.1 - 0.00016 21.5 0.0 0.022 14.6 0.0 3.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KER20747.1 - 0.027 14.5 2.0 8.8 6.5 0.0 4.2 5 0 0 5 5 5 0 Limkain b1 Ank_2 PF12796.7 KER20748.1 - 1.3e-18 67.4 4.8 6.7e-08 33.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 KER20748.1 - 1.5e-17 63.9 15.3 1.5e-17 63.9 15.3 3.5 2 1 0 2 2 1 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KER20748.1 - 4.4e-17 62.2 5.3 2.8e-05 24.6 0.2 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER20748.1 - 2.6e-12 46.7 4.8 0.015 15.7 0.1 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER20748.1 - 8e-12 44.3 11.1 0.057 14.0 0.1 6.8 7 0 0 7 7 6 3 Ankyrin repeat Ank PF00023.30 KER20748.1 - 2.9e-11 43.3 11.4 0.019 15.4 0.2 6.4 6 0 0 6 6 6 3 Ankyrin repeat DUF975 PF06161.11 KER20748.1 - 0.016 15.0 1.5 0.016 15.0 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF975) DUF3328 PF11807.8 KER20748.1 - 0.08 12.7 0.2 0.08 12.7 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) Nop10p PF04135.12 KER20748.1 - 0.17 12.0 3.2 9.2 6.4 0.1 3.3 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family SEO_C PF14577.6 KER20748.1 - 2.5 7.5 3.7 3.9 6.9 3.7 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus TssN PF17555.2 KER20748.1 - 3.2 7.0 17.5 0.015 14.7 3.4 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Proteasom_PSMB PF10508.9 KER20749.1 - 2.1e-40 138.7 0.1 1.8e-21 76.2 0.0 2.8 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 KER20749.1 - 0.012 16.0 0.8 21 5.6 0.0 3.8 3 1 0 3 3 3 0 HEAT repeats FliS_cochap PF16522.5 KER20749.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 DNA_pol_phi PF04931.13 KER20750.1 - 9e-26 90.2 36.1 5.9e-20 71.0 19.1 4.9 4 2 0 4 4 4 3 DNA polymerase phi DASH_Hsk3 PF08227.11 KER20753.1 - 0.066 13.6 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like SprT-like PF10263.9 KER20755.1 - 2.2e-28 98.4 0.1 6.8e-28 96.8 0.0 1.9 2 0 0 2 2 2 1 SprT-like family RVT_1 PF00078.27 KER20756.1 - 0.0059 16.2 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RE_TaqI PF09573.10 KER20757.1 - 0.0074 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 TaqI restriction endonuclease ig PF00047.25 KER20757.1 - 0.18 12.0 2.2 0.49 10.6 2.2 1.9 1 1 0 1 1 1 0 Immunoglobulin domain 7tm_1 PF00001.21 KER20758.1 - 1.6e-08 34.2 18.0 1.6e-08 34.2 18.0 3.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.9 KER20758.1 - 0.0031 17.1 42.6 0.1 12.1 16.5 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srbc DBC1 PF14443.6 KER20758.1 - 0.016 15.1 0.4 8 6.5 0.1 2.3 2 0 0 2 2 2 0 DBC1 NADH_B2 PF14813.6 KER20758.1 - 6.4 6.6 10.8 22 4.9 1.9 3.1 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 SNF PF00209.18 KER20761.1 - 9.4e-198 658.1 34.6 1.1e-197 657.9 34.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KER20762.1 - 1.1e-191 638.1 34.8 3.1e-103 346.3 20.6 2.0 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family LMBR1 PF04791.16 KER20762.1 - 4.2e-05 22.7 0.2 9.3e-05 21.5 0.2 1.5 1 0 0 1 1 1 1 LMBR1-like membrane protein Dynein_light PF01221.18 KER20765.1 - 1.3e-14 54.3 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 KER20765.1 - 7.1e-07 28.3 0.2 0.00062 19.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER20765.1 - 7.9e-06 25.4 0.9 0.0061 16.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER20765.1 - 1.1e-05 25.8 0.8 1.1e-05 25.8 0.8 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KER20765.1 - 0.00016 21.4 0.4 0.069 13.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair HTH_Mga PF08280.11 KER20765.1 - 0.17 11.9 1.1 2 8.5 0.0 3.1 2 2 2 4 4 4 0 M protein trans-acting positive regulator (MGA) HTH domain DcpS_C PF11969.8 KER20765.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Peptidase_C13 PF01650.18 KER20766.1 - 1e-95 320.1 2.6 1.4e-95 319.7 2.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20766.1 - 0.0096 15.9 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER20768.1 - 2.3e-88 296.0 3.0 3.3e-88 295.5 3.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20768.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER20768.1 - 0.03 13.5 0.1 0.077 12.2 0.0 1.6 1 1 1 2 2 2 0 Peptidase family C25 Peptidase_C13 PF01650.18 KER20769.1 - 2.1e-90 302.7 2.4 2.3e-90 302.5 1.4 1.5 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER20769.1 - 0.0052 16.8 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER20769.1 - 0.0097 15.1 0.1 0.022 14.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase family C25 Peptidase_C13 PF01650.18 KER20771.1 - 5e-51 173.7 11.0 1.9e-17 63.6 0.6 3.7 3 1 1 4 4 4 3 Peptidase C13 family PAS_4 PF08448.10 KER20771.1 - 0.017 15.3 0.1 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 PAS fold Phage_T4_gp36 PF03903.13 KER20771.1 - 0.056 13.4 0.0 6.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Phage T4 tail fibre HYR PF02494.16 KER20772.1 - 0.00053 20.3 2.8 0.71 10.2 0.0 3.1 4 0 0 4 4 4 2 HYR domain Ig_2 PF13895.6 KER20772.1 - 0.00089 19.5 0.8 48 4.4 0.0 4.1 3 1 1 4 4 4 0 Immunoglobulin domain DUF1964 PF09244.10 KER20772.1 - 0.0009 19.6 0.3 6.1 7.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1964) FAA_hydro_N_2 PF18288.1 KER20772.1 - 0.006 17.0 0.0 5.9 7.4 0.0 2.3 2 0 0 2 2 2 2 Fumarylacetoacetase N-terminal domain 2 Reg_prop PF07494.11 KER20772.1 - 0.033 14.4 0.0 37 5.0 0.0 3.6 4 0 0 4 4 4 0 Two component regulator propeller DUF108 PF01958.18 KER20772.1 - 0.093 13.1 0.0 29 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF108 DUF1155 PF06633.11 KER20772.1 - 0.57 9.7 3.8 12 5.4 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1155) DUF3267 PF11667.8 KER20773.1 - 0.31 11.3 0.2 0.31 11.3 0.2 3.2 3 0 0 3 3 3 0 Putative zincin peptidase LRR19-TM PF15176.6 KER20773.1 - 0.34 10.9 2.2 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain RIO1 PF01163.22 KER20775.1 - 1.5e-61 207.3 0.0 3.1e-61 206.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RVT_1 PF00078.27 KER20775.1 - 2.9e-13 49.9 0.0 5.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_fungal PF17667.1 KER20775.1 - 0.014 14.2 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Toxin-JAB1 PF15659.6 KER20775.1 - 0.089 13.1 1.2 18 5.8 0.1 2.5 2 0 0 2 2 2 0 JAB-like toxin 1 AdenylateSensor PF16579.5 KER20775.1 - 0.67 10.4 5.8 6.4 7.3 0.6 2.7 2 0 0 2 2 2 0 Adenylate sensor of SNF1-like protein kinase Baculo_VP91_N PF08475.10 KER20775.1 - 1.2 8.7 6.3 7.5 6.2 0.7 2.4 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal RWD PF05773.22 KER20776.1 - 1e-17 64.5 0.8 1.8e-17 63.7 0.8 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KER20776.1 - 5.6e-06 26.8 4.7 1.8e-05 25.2 4.3 2.0 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 MMR_HSR1_C PF08438.10 KER20776.1 - 0.085 13.4 0.2 0.9 10.1 0.0 2.5 2 2 1 3 3 3 0 GTPase of unknown function C-terminal Peptidase_M24 PF00557.24 KER20776.1 - 0.13 11.9 0.7 0.25 11.0 0.2 1.7 1 1 1 2 2 2 0 Metallopeptidase family M24 ZapB PF06005.12 KER20776.1 - 0.95 10.0 11.9 1.6 9.3 7.8 2.7 2 1 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KER20776.1 - 5.7 7.4 7.2 5.2 7.5 4.7 2.2 2 1 0 2 2 2 0 Centromere protein H (CENP-H) CUB PF00431.20 KER20779.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain CUB PF00431.20 KER20780.1 - 3.4e-07 30.6 0.1 3.1e-06 27.5 0.0 2.5 3 1 1 4 4 4 1 CUB domain DUF870 PF05912.11 KER20780.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) E1_DerP2_DerF2 PF02221.15 KER20781.1 - 0.00028 21.3 0.0 0.0021 18.5 0.0 2.3 3 0 0 3 3 3 1 ML domain WD40 PF00400.32 KER20783.1 - 7.9e-37 124.6 24.8 3e-08 34.2 0.9 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KER20783.1 - 5.5e-17 62.2 0.9 1e-15 58.1 0.9 2.2 1 1 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KER20783.1 - 9.2e-14 51.5 0.0 0.008 16.5 0.0 5.4 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KER20783.1 - 0.0077 15.6 0.2 2.2 7.5 0.0 3.5 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KER20783.1 - 0.017 15.0 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KER20783.1 - 0.051 12.2 0.2 5.7 5.4 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DHR-2 PF06920.13 KER20788.1 - 1.8e-125 419.6 0.0 4.9e-125 418.2 0.0 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KER20788.1 - 5.6e-44 150.3 0.0 1.2e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 KER20788.1 - 3.3e-10 40.4 0.0 8.4e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) Phostensin_N PF13916.6 KER20789.1 - 0.09 13.1 1.8 0.8 10.1 0.0 2.9 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal BRO1 PF03097.18 KER20791.1 - 9.3e-30 103.7 0.4 4.8e-21 75.0 0.1 2.0 2 0 0 2 2 2 2 BRO1-like domain Ax_dynein_light PF10211.9 KER20795.1 - 4.8e-95 316.8 14.2 5.8e-95 316.6 14.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 KER20795.1 - 0.00029 19.7 13.3 0.00029 19.7 13.3 1.5 1 1 0 1 1 1 1 RIB43A UPF0242 PF06785.11 KER20795.1 - 0.0017 18.5 6.3 0.0017 18.5 6.3 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus TSNAXIP1_N PF15739.5 KER20795.1 - 0.0018 18.6 13.8 0.51 10.7 11.0 2.4 1 1 1 2 2 2 2 Translin-associated factor X-interacting N-terminus HALZ PF02183.18 KER20795.1 - 0.021 15.0 4.5 0.36 11.1 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper FapA PF03961.13 KER20795.1 - 0.13 10.8 4.7 0.17 10.5 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A End3 PF12761.7 KER20795.1 - 0.14 12.4 9.5 0.04 14.1 6.1 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF5320 PF17253.2 KER20795.1 - 0.23 12.6 8.5 2.9 9.0 1.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Syntaxin-6_N PF09177.11 KER20795.1 - 0.45 11.1 11.1 0.044 14.3 6.2 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-C4pol PF14260.6 KER20795.1 - 0.49 10.9 3.0 0.47 11.0 0.6 2.2 2 1 0 2 2 1 0 C4-type zinc-finger of DNA polymerase delta Peptidase_S46 PF10459.9 KER20795.1 - 0.52 8.9 5.7 0.65 8.6 5.7 1.1 1 0 0 1 1 1 0 Peptidase S46 APG6_N PF17675.1 KER20795.1 - 0.7 10.4 22.4 2.1 8.9 21.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Striatin PF08232.12 KER20795.1 - 1 10.0 14.3 0.3 11.7 11.2 1.6 2 0 0 2 2 2 0 Striatin family FlaC_arch PF05377.11 KER20795.1 - 1.5 9.3 4.5 20 5.6 0.7 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 KER20795.1 - 1.6 9.0 20.7 35 4.6 20.8 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 KER20795.1 - 1.6 9.4 15.4 3.6 8.2 11.6 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Remorin_C PF03763.13 KER20795.1 - 1.7 8.6 12.8 4 7.4 12.8 1.6 1 0 0 1 1 1 0 Remorin, C-terminal region PRKG1_interact PF15898.5 KER20795.1 - 2.8 8.9 16.4 4.4 8.3 14.1 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 KER20795.1 - 3.2 7.5 12.6 1.8 8.4 10.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Mei5 PF10376.9 KER20795.1 - 3.5 7.4 13.3 4 7.2 12.7 1.5 1 1 0 1 1 1 0 Double-strand recombination repair protein DivIC PF04977.15 KER20795.1 - 3.9 7.3 19.6 0.11 12.3 5.2 2.9 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.8 KER20795.1 - 4 7.5 16.7 0.4 10.8 12.1 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KER20795.1 - 4 7.8 15.4 7.1 7.0 13.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1515 PF07439.11 KER20795.1 - 8.8 6.4 7.5 2.8 8.0 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) ELYS-bb PF16687.5 KER20796.1 - 2.1e-20 72.8 1.2 7e-15 54.6 0.0 2.6 3 0 0 3 3 3 2 beta-propeller of ELYS nucleoporin ELYS PF13934.6 KER20796.1 - 9.6e-09 35.5 0.1 2.3e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly Peptidase_C97 PF05903.14 KER20799.1 - 3.1e-37 127.7 0.0 4.9e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Sortilin-Vps10 PF15902.5 KER20803.1 - 2e-59 201.5 0.1 2.1e-28 99.3 0.2 3.0 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KER20803.1 - 1.4e-17 64.6 0.0 2.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KER20803.1 - 5.6e-07 28.6 15.0 2.9 8.2 0.1 6.0 5 0 0 5 5 5 4 BNR/Asp-box repeat BNR_6 PF15899.5 KER20803.1 - 3 8.2 5.0 1.1e+02 3.3 0.1 4.7 5 0 0 5 5 5 0 BNR-Asp box repeat RVT_1 PF00078.27 KER20804.1 - 2.4e-06 27.2 0.0 2.5e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KER20806.1 - 4.1e-79 261.1 6.1 1.7e-16 60.4 0.1 10.7 9 2 1 10 10 10 8 Cadherin domain Cadherin_2 PF08266.12 KER20806.1 - 3.2e-07 30.1 1.5 0.37 10.6 0.1 5.8 6 0 0 6 6 6 3 Cadherin-like RVT_1 PF00078.27 KER20807.1 - 4.6e-44 150.6 0.0 7.4e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf_Hakai PF18408.1 KER20807.1 - 5.2e-17 61.2 2.3 5.2e-17 61.2 2.3 2.3 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain Exo_endo_phos_2 PF14529.6 KER20807.1 - 1.1e-05 25.2 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HMG_box PF00505.19 KER20809.1 - 5.2e-37 126.1 16.7 5.4e-21 74.8 4.7 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KER20809.1 - 1.3e-29 102.6 19.1 1.6e-17 63.9 5.6 2.1 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 KER20809.1 - 0.012 15.6 2.5 0.012 15.6 2.5 2.4 2 1 0 2 2 2 0 HMG (high mobility group) box 5 MEIOC PF15189.6 KER20809.1 - 0.9 9.1 7.0 1.3 8.6 1.0 2.2 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC FTCD_C PF04961.12 KER20809.1 - 1.2 8.8 5.6 0.21 11.3 1.7 1.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase YABBY PF04690.13 KER20809.1 - 2 8.9 7.9 0.65 10.5 5.0 1.6 1 1 1 2 2 2 0 YABBY protein PhoLip_ATPase_C PF16212.5 KER20810.1 - 2e-82 276.7 21.9 2e-82 276.7 21.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KER20810.1 - 3.4e-28 97.1 1.4 1.1e-27 95.5 1.4 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KER20810.1 - 2.6e-12 46.7 0.0 2.4e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KER20810.1 - 4e-11 43.6 0.9 6.8e-05 23.3 0.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KER20810.1 - 2.7e-10 40.1 0.0 1.5e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KER20810.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Intein_splicing PF14890.6 KER20810.1 - 0.096 12.6 0.0 0.69 9.9 0.0 1.5 1 1 0 1 1 1 0 Intein splicing domain XTBD PF11952.8 KER20811.1 - 1.7e-16 59.7 0.0 2.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 XRN-Two Binding Domain, XTBD Transposase_22 PF02994.14 KER20812.1 - 0.24 11.6 4.9 0.083 13.1 1.7 2.0 2 0 0 2 2 2 0 L1 transposable element RBD-like domain DUF948 PF06103.11 KER20812.1 - 0.42 10.9 3.7 2.3 8.6 0.3 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 KER20812.1 - 8.2 6.7 40.5 2.3 8.5 5.3 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Tctex-1 PF03645.13 KER20813.1 - 0.00076 19.7 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family DUF4167 PF13763.6 KER20813.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Methyltransf_23 PF13489.6 KER20814.1 - 2.6e-16 59.9 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER20814.1 - 2.9e-13 50.3 0.2 1.7e-11 44.6 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER20814.1 - 2.9e-10 40.7 0.0 6.8e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER20814.1 - 1.2e-09 38.7 0.1 4.3e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER20814.1 - 1.1e-07 31.8 0.0 1e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KER20814.1 - 8e-05 22.1 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KER20814.1 - 0.0052 16.4 1.1 2.3 7.7 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.18 KER20814.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KER20814.1 - 0.18 11.8 0.1 1.9 8.5 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF4201 PF13870.6 KER20815.1 - 0.0019 18.0 0.2 0.0019 18.0 0.2 7.7 7 1 0 7 7 7 1 Domain of unknown function (DUF4201) ATG16 PF08614.11 KER20815.1 - 0.009 16.3 15.2 0.009 16.3 15.2 7.4 4 2 2 7 7 7 1 Autophagy protein 16 (ATG16) Atypical_Card PF18461.1 KER20815.1 - 0.87 9.8 4.6 2.4 8.4 0.1 3.5 3 0 0 3 3 3 0 Atypical caspase recruitment domain DUF1664 PF07889.12 KER20815.1 - 3.4 7.7 0.0 1.8 8.6 0.2 8.2 7 2 1 8 8 8 0 Protein of unknown function (DUF1664) Peptidase_C1 PF00112.23 KER20816.1 - 7.4e-57 192.9 0.0 1e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 KER20816.1 - 1.7e-23 83.1 0.2 2.6e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 KER20816.1 - 1.4e-05 24.1 0.0 0.00038 19.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Propeptide_C1 PF08127.13 KER20816.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Keratin_assoc PF09775.9 KER20818.1 - 2.4e-45 153.3 4.8 2.7e-45 153.2 4.8 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Phage_holin_8 PF16931.5 KER20818.1 - 0.057 13.4 1.2 0.17 11.9 1.2 2.0 1 1 0 1 1 1 0 Putative phage holin DUF2254 PF10011.9 KER20818.1 - 0.29 9.9 2.8 0.35 9.6 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) TFIIB PF00382.19 KER20820.1 - 1.6e-25 88.9 0.1 1.5e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KER20820.1 - 1.7e-08 33.8 3.7 3.7e-08 32.7 3.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding BRF1 PF07741.13 KER20820.1 - 4.3e-06 27.0 1.1 1.7e-05 25.1 1.1 2.1 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KER20820.1 - 0.0099 15.6 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER20820.1 - 0.046 13.8 0.1 11 6.1 0.0 3.0 3 0 0 3 3 3 0 Cyclin, C-terminal domain SKA1 PF07160.12 KER20820.1 - 5.3 6.8 6.6 5.7 6.7 1.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Neil1-DNA_bind PF09292.10 KER20822.1 - 0.13 12.2 0.2 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind DUF4880 PF16220.5 KER20822.1 - 0.15 11.9 1.6 3.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) RAP1 PF07218.11 KER20822.1 - 0.18 10.1 0.0 8.6 4.5 0.0 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) HAUS2 PF15003.6 KER20823.1 - 0.00056 19.7 1.9 0.00066 19.5 1.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 AAA_23 PF13476.6 KER20823.1 - 0.3 11.6 7.3 0.36 11.3 7.3 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KER20823.1 - 0.35 10.9 3.0 0.67 10.0 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PPP4R2 PF09184.11 KER20824.1 - 0.00086 19.0 4.0 0.0014 18.3 4.0 1.4 1 0 0 1 1 1 1 PPP4R2 Paf1 PF03985.13 KER20824.1 - 0.0078 15.3 5.4 0.012 14.6 5.4 1.2 1 0 0 1 1 1 1 Paf1 Myc_N PF01056.18 KER20824.1 - 0.0084 16.1 3.2 0.014 15.4 3.2 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Pox_Ag35 PF03286.14 KER20824.1 - 0.074 12.8 4.2 0.15 11.9 4.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 KER20824.1 - 0.075 13.3 11.8 0.22 11.7 11.8 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRM_DME PF15628.6 KER20824.1 - 0.15 12.3 0.2 0.37 11.0 0.2 1.6 1 0 0 1 1 1 0 RRM in Demeter FeoA PF04023.14 KER20824.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 FeoA domain Astro_capsid_p PF12226.8 KER20824.1 - 0.38 9.8 14.9 0.66 9.1 14.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 KER20824.1 - 0.4 9.9 6.4 0.71 9.0 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KER20824.1 - 0.54 8.4 14.3 0.83 7.8 14.3 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 KER20824.1 - 0.69 9.9 23.2 1.2 9.1 23.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 KER20824.1 - 0.71 9.2 12.9 1 8.8 12.9 1.1 1 0 0 1 1 1 0 SDA1 CAF1A PF12253.8 KER20824.1 - 2.8 8.2 16.4 6.2 7.1 16.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A PI3K_1B_p101 PF10486.9 KER20824.1 - 3.1 5.5 7.8 4.7 4.9 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4637 PF15470.6 KER20824.1 - 5.7 6.6 10.3 11 5.7 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 KER20824.1 - 7.4 4.7 10.4 11 4.1 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 KER20824.1 - 8.9 5.6 6.4 1.8 7.9 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) XPG_I PF00867.18 KER20825.1 - 2.1e-20 72.9 0.0 5e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KER20825.1 - 3.7e-05 23.3 0.2 5.9e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 XPG domain containing FCH PF00611.23 KER20827.1 - 3.4e-13 49.7 0.4 3.4e-13 49.7 0.4 3.0 4 1 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain Filament PF00038.21 KER20827.1 - 0.0099 15.5 3.3 0.0099 15.5 3.3 2.0 2 0 0 2 2 2 1 Intermediate filament protein SH3_1 PF00018.28 KER20827.1 - 0.046 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SH3BP5 PF05276.14 KER20827.1 - 0.38 10.5 8.4 0.76 9.5 1.1 2.4 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Tropomyosin PF00261.20 KER20827.1 - 1.3 8.4 10.3 0.046 13.1 4.2 1.7 2 0 0 2 2 2 0 Tropomyosin DUF4200 PF13863.6 KER20827.1 - 4.4 7.7 11.3 3.4 8.1 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Rho_Binding PF08912.11 KER20827.1 - 9.8 7.1 9.9 0.53 11.1 2.1 2.8 2 1 1 3 3 3 0 Rho Binding CDRN PF05174.12 KER20828.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus CDRN PF05174.12 KER20829.1 - 0.085 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus Lectin_C PF00059.21 KER20831.1 - 9.3e-06 26.3 0.1 1.3e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 Lectin C-type domain Pigment_DH PF06324.11 KER20832.1 - 0.17 12.1 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) START PF01852.19 KER20834.1 - 1.8e-17 63.4 0.0 1.1e-16 60.9 0.0 2.0 1 1 0 1 1 1 1 START domain DUF2380 PF09533.10 KER20837.1 - 0.057 13.0 0.0 0.059 13.0 0.0 1.0 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) RA PF00788.23 KER20839.1 - 1.2e-06 29.1 0.0 2.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain UL16 PF17622.2 KER20839.1 - 0.19 11.4 0.0 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Viral unique long protein 16 Peptidase_M29 PF02073.15 KER20839.1 - 0.41 9.4 3.0 0.3 9.8 1.1 1.5 1 1 1 2 2 2 0 Thermophilic metalloprotease (M29) FAM76 PF16046.5 KER20839.1 - 0.59 9.4 2.2 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 FAM76 protein ADIP PF11559.8 KER20839.1 - 1.4 9.0 17.6 0.47 10.5 3.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATP_bind_1 PF03029.17 KER20841.1 - 9.1e-72 241.7 0.1 7.6e-46 156.8 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KER20841.1 - 5.7e-05 23.1 0.0 0.00072 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KER20841.1 - 0.0009 19.5 0.0 0.0045 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KER20841.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 KER20841.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 KER20841.1 - 0.0027 17.8 0.0 0.0036 17.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KER20841.1 - 0.003 18.0 0.0 0.023 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ArsA_ATPase PF02374.15 KER20841.1 - 0.0034 16.6 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA PF00004.29 KER20841.1 - 0.0044 17.4 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KER20841.1 - 0.0056 15.7 0.0 0.0091 15.0 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KER20841.1 - 0.0072 16.9 0.1 0.051 14.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.6 KER20841.1 - 0.016 15.7 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KER20841.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KER20841.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KER20841.1 - 0.039 14.1 0.0 0.09 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KER20841.1 - 0.039 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KER20841.1 - 0.07 13.6 0.0 0.3 11.6 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 KER20841.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KER20841.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KER20841.1 - 0.11 12.5 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KER20841.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KER20841.1 - 0.15 12.0 0.0 0.85 9.5 0.0 2.0 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 KER20841.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTP_transf_2 PF01909.23 KER20842.1 - 0.00014 22.1 0.1 0.00026 21.2 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KER20842.1 - 0.14 12.2 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase WD40 PF00400.32 KER20843.1 - 3.1e-10 40.4 8.8 1.4e-06 28.9 0.1 6.0 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20843.1 - 0.00025 21.3 0.0 4.2 7.7 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KER20843.1 - 0.071 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 CNH domain PUF PF00806.19 KER20844.1 - 3.3e-64 209.1 9.8 1.4e-09 37.1 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KER20844.1 - 0.014 15.7 0.7 4.4 7.6 0.1 4.1 3 1 1 4 4 4 0 CPL (NUC119) domain DUF4055 PF13264.6 KER20844.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Rib_5-P_isom_A PF06026.14 KER20845.1 - 7.9e-55 185.1 0.0 9.7e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KER20845.1 - 0.0091 15.9 0.2 0.84 9.6 0.1 2.1 2 0 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 KER20845.1 - 0.032 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain INTS2 PF14750.6 KER20846.1 - 1.6e-147 492.9 15.5 4.1e-108 362.4 2.1 3.7 1 1 1 2 2 2 2 Integrator complex subunit 2 7tm_1 PF00001.21 KER20847.1 - 2e-19 70.0 3.0 3.1e-19 69.3 2.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER20847.1 - 2.5e-08 33.9 4.1 2.5e-08 33.9 4.1 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KER20847.1 - 2.6e-08 33.5 13.1 6.8e-08 32.2 5.1 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KER20847.1 - 0.13 11.6 18.1 0.069 12.5 10.6 2.8 2 2 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 KER20847.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.8 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM154 PF15102.6 KER20847.1 - 0.22 11.4 3.3 0.21 11.5 0.3 2.3 2 0 0 2 2 2 0 TMEM154 protein family Nsp1_C PF05064.13 KER20849.1 - 8.3e-31 106.2 5.9 1.7e-30 105.2 5.9 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region WD40 PF00400.32 KER20849.1 - 2e-19 69.5 9.5 7.7e-05 23.4 0.1 8.3 8 1 0 8 8 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20849.1 - 6e-06 26.5 0.0 0.016 15.5 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 KER20849.1 - 0.00021 21.6 3.3 0.00046 20.5 3.3 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KER20849.1 - 0.013 16.0 3.0 0.026 15.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 ALIX_LYPXL_bnd PF13949.6 KER20849.1 - 0.043 13.1 3.9 0.068 12.5 3.9 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_23 PF13476.6 KER20849.1 - 0.046 14.2 0.0 0.069 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 KER20849.1 - 0.082 12.8 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF4200 PF13863.6 KER20849.1 - 0.12 12.8 4.0 0.2 12.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 KER20849.1 - 0.23 11.0 3.9 0.36 10.4 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KER20849.1 - 0.28 10.4 3.5 0.62 9.3 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF148 PF02520.17 KER20849.1 - 0.41 10.8 2.9 7.8 6.7 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 APG6_N PF17675.1 KER20849.1 - 3.3 8.2 10.2 5.8 7.5 10.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KER20849.1 - 5.4 7.3 6.8 1.1 9.5 3.3 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding PsbW PF07123.12 KER20850.1 - 0.051 13.6 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Arteri_nucleo PF01481.16 KER20851.1 - 0.063 13.6 0.3 0.063 13.6 0.3 1.8 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein LicD PF04991.13 KER20852.1 - 4e-06 27.2 0.6 8.7e-06 26.0 0.6 1.4 1 0 0 1 1 1 1 LicD family UPF0203 PF05254.12 KER20853.1 - 8.3e-16 58.0 0.1 1.1e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KER20853.1 - 0.013 15.8 1.0 0.039 14.3 0.6 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 KER20853.1 - 0.051 13.6 0.9 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KER20853.1 - 0.096 13.0 2.7 4.6 7.6 0.4 2.2 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KER20853.1 - 0.1 12.6 1.0 1.4 9.0 1.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like RF-1 PF00472.20 KER20854.1 - 0.00016 21.6 1.3 0.00021 21.2 1.3 1.2 1 0 0 1 1 1 1 RF-1 domain Laminin_EGF PF00053.24 KER20855.1 - 2.6e-116 379.6 338.7 1.6e-09 37.8 14.7 19.8 15 3 4 19 19 19 19 Laminin EGF domain Laminin_N PF00055.17 KER20855.1 - 6.1e-51 173.3 0.0 6.1e-51 173.3 0.0 3.1 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 KER20855.1 - 1.6e-20 73.3 0.0 3.8e-15 56.0 0.0 3.6 2 1 0 2 2 2 2 Laminin B (Domain IV) Laminin_G_2 PF02210.24 KER20855.1 - 1e-07 32.6 0.0 0.19 12.3 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain Presenilin PF01080.17 KER20855.1 - 2.9 6.6 5.4 6 5.5 5.4 1.4 1 0 0 1 1 1 0 Presenilin bZIP_1 PF00170.21 KER20856.1 - 0.35 11.0 25.2 0.066 13.3 1.8 5.6 4 1 1 5 5 5 0 bZIP transcription factor IFP_35_N PF07334.13 KER20856.1 - 2.2 8.4 23.1 0.46 10.6 0.3 5.2 5 1 0 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pns11_12 PF17464.2 KER20860.1 - 0.07 12.8 0.0 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Non-structural protein 11 and 12 Fer4_21 PF14697.6 KER20860.1 - 5.1 7.3 11.3 5.8 7.1 0.6 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain 7tm_1 PF00001.21 KER20861.1 - 1.4e-15 57.3 0.9 1.6e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PK PF00224.21 KER20867.1 - 2.4e-154 513.4 0.2 2.2e-88 296.5 0.0 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 KER20867.1 - 6.5e-32 110.2 0.0 1.4e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 KER20867.1 - 0.25 10.3 3.3 0.51 9.3 0.0 2.5 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain KH_1 PF00013.29 KER20870.1 - 1.9e-29 101.3 3.3 2.5e-16 59.2 2.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KER20870.1 - 1.8e-08 34.1 1.3 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KER20870.1 - 0.00063 19.8 0.6 0.16 12.1 0.2 2.5 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 KER20870.1 - 0.0031 17.4 0.1 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 KH domain MOEP19 PF16005.5 KER20870.1 - 0.076 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 KH-like RNA-binding domain LAT PF15234.6 KER20875.1 - 0.21 11.3 0.1 0.21 11.3 0.1 3.6 2 1 0 2 2 2 0 Linker for activation of T-cells DNA_pol_phi PF04931.13 KER20875.1 - 0.25 9.4 39.4 0.02 13.0 31.7 2.0 2 0 0 2 2 2 0 DNA polymerase phi Nop25 PF09805.9 KER20875.1 - 0.33 11.4 10.7 0.16 12.5 7.6 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 KER20875.1 - 0.55 9.5 19.9 0.18 11.1 15.1 2.0 2 0 0 2 2 2 0 BUD22 CNDH2_C PF16858.5 KER20875.1 - 0.62 9.9 8.2 0.19 11.6 4.9 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 KER20875.1 - 0.64 8.7 6.9 1 8.1 6.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KER20875.1 - 4.5 5.3 29.8 0.23 9.7 23.4 1.8 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.12 KER20875.1 - 4.8 5.5 22.9 8.3 4.7 18.2 2.0 2 0 0 2 2 2 0 Mpp10 protein PH PF00169.29 KER20876.1 - 1.2e-05 25.8 0.0 0.016 15.7 0.0 2.7 2 0 0 2 2 2 2 PH domain UTRA PF07702.13 KER20877.1 - 0.036 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 UTRA domain Wtap PF17098.5 KER20878.1 - 2.1e-42 144.7 0.0 8.6e-42 142.7 0.0 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family CENP-F_leu_zip PF10473.9 KER20878.1 - 0.0033 17.5 10.1 0.016 15.3 0.9 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 KER20878.1 - 0.0044 16.4 1.0 0.0044 16.4 1.0 2.2 2 0 0 2 2 2 1 Rabaptin-like protein SlyX PF04102.12 KER20878.1 - 0.025 15.2 5.8 0.78 10.4 0.2 2.7 2 0 0 2 2 2 0 SlyX Phage_GP20 PF06810.11 KER20878.1 - 0.26 11.1 4.5 5.5 6.8 0.2 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Filament PF00038.21 KER20878.1 - 0.41 10.2 8.9 1.2 8.7 0.5 2.4 2 0 0 2 2 2 0 Intermediate filament protein Med9 PF07544.13 KER20878.1 - 1.1 9.4 5.1 69 3.6 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Asp PF00026.23 KER20879.1 - 4.4e-18 65.8 0.0 5.2e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER20879.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal WD40 PF00400.32 KER20882.1 - 7.5e-35 118.4 18.8 1.5e-06 28.8 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KER20882.1 - 7.3e-07 29.0 0.6 2.4e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER20882.1 - 0.00014 21.7 0.1 0.00032 20.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain RA PF00788.23 KER20883.1 - 0.0028 18.2 0.0 0.006 17.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 KER20883.1 - 0.023 15.2 0.7 0.082 13.4 0.7 2.0 1 1 0 1 1 1 0 PH domain Spatacsin_C PF14649.6 KER20884.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Pribosyl_synth PF14572.6 KER20887.1 - 3.3e-42 144.6 0.0 5.6e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KER20887.1 - 1.3e-35 121.9 0.0 1.8e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KER20887.1 - 3.6e-07 29.8 0.0 6.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ig_3 PF13927.6 KER20888.1 - 2.8e-15 56.7 3.9 9.9e-11 42.1 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KER20888.1 - 5.3e-15 55.5 0.2 4.4e-10 39.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER20888.1 - 4.5e-14 52.3 0.0 1.3e-07 31.6 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KER20888.1 - 2.3e-13 50.1 1.5 7.8e-08 32.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER20888.1 - 1.9e-06 28.0 3.3 0.4 10.9 0.1 3.8 2 2 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KER20888.1 - 0.002 17.6 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain DUF3377 PF11857.8 KER20888.1 - 0.039 13.9 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TNFR_16_TM PF18422.1 KER20888.1 - 0.11 12.4 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Ig_4 PF16680.5 KER20888.1 - 0.16 12.3 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain HrpB7 PF09486.10 KER20891.1 - 0.005 17.2 3.6 0.005 17.2 3.6 7.7 4 3 0 5 5 5 2 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 KER20891.1 - 0.0094 15.6 89.5 0.059 13.0 6.3 6.2 2 2 2 4 4 4 4 Intermediate filament protein Sulfate_transp PF00916.20 KER20892.1 - 9e-66 222.2 34.4 1.4e-31 109.6 6.5 3.6 4 0 0 4 4 4 3 Sulfate permease family STAS PF01740.21 KER20892.1 - 1e-13 51.0 0.0 1.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF1759 PF03564.15 KER20893.1 - 4.3e-12 46.2 0.0 7.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) PCO_ADO PF07847.12 KER20894.1 - 6.1e-45 153.2 0.0 7.2e-44 149.6 0.0 2.0 1 1 0 1 1 1 1 PCO_ADO Cupin_1 PF00190.22 KER20894.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Cupin zf-RING_2 PF13639.6 KER20896.1 - 1.1e-09 38.4 9.6 1.8e-09 37.7 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KER20896.1 - 1.8e-07 30.9 5.4 3e-07 30.2 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER20896.1 - 5.1e-07 29.4 6.3 8.2e-07 28.8 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER20896.1 - 1.6e-06 28.3 8.9 4.1e-06 27.0 8.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain CUE PF02845.16 KER20896.1 - 6e-06 25.8 0.1 2.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 CUE domain zf-C3HC4_3 PF13920.6 KER20896.1 - 5.5e-05 22.9 3.1 8.7e-05 22.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER20896.1 - 0.00029 20.8 1.5 0.00058 19.9 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KER20896.1 - 0.00062 19.7 4.0 0.00098 19.0 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER20896.1 - 0.0011 18.9 3.2 0.0021 18.1 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KER20896.1 - 0.006 16.3 2.4 0.012 15.3 2.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KER20896.1 - 0.011 15.6 4.1 0.02 14.7 4.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KER20896.1 - 0.28 10.8 5.1 0.58 9.8 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KER20896.1 - 0.46 10.7 3.6 1.1 9.4 3.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KER20896.1 - 0.48 10.2 6.7 0.052 13.4 1.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KER20896.1 - 5.5 7.4 5.6 9.7 6.6 5.6 1.4 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.25 KER20902.1 - 2.4e-64 217.2 0.0 4.2e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20902.1 - 1.2e-37 129.6 0.0 1.8e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER20902.1 - 1.6e-12 47.3 0.0 3.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER20902.1 - 3.7e-05 23.2 0.7 7.5e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER20902.1 - 0.0017 18.0 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KER20902.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 KER20904.1 - 6.6e-24 84.7 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ribosomal_L9_N PF01281.19 KER20904.1 - 5.2e-10 38.7 0.0 1.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain FtsJ PF01728.19 KER20904.1 - 0.00017 21.8 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KER20904.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PB1 PF00564.24 KER20905.1 - 2.6e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 KER20905.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER20905.1 - 9.7e-07 28.5 0.1 1.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain bZIP_1 PF00170.21 KER20906.1 - 7.1e-12 45.2 9.5 1.3e-11 44.4 9.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KER20906.1 - 4.7e-07 29.8 11.7 8.6e-07 29.0 11.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KER20906.1 - 0.0031 18.0 9.3 0.0059 17.1 9.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Tho2 PF11262.8 KER20906.1 - 0.086 12.0 1.1 0.14 11.4 1.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 cwf21 PF08312.12 KER20907.1 - 2.5e-13 49.9 4.5 2.5e-13 49.9 4.5 2.6 2 1 0 2 2 2 1 cwf21 domain SWIRM-assoc_2 PF16496.5 KER20907.1 - 0.029 13.2 11.0 0.058 12.3 11.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MAT1 PF06391.13 KER20907.1 - 1.6 8.5 16.8 0.077 12.8 7.2 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 WIF PF02019.18 KER20909.1 - 2.1e-16 59.8 0.0 3.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 WIF domain DNA_primase_S PF01896.19 KER20910.1 - 9.9e-47 159.2 0.0 1.3e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit QVR PF17064.5 KER20913.1 - 5.5e-27 93.9 12.0 7e-27 93.5 12.0 1.1 1 0 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 KER20913.1 - 0.0014 18.7 6.2 0.0014 18.7 6.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF753) Activin_recp PF01064.23 KER20913.1 - 0.31 12.2 12.3 0.48 11.5 12.3 1.3 1 0 0 1 1 1 0 Activin types I and II receptor domain LIM PF00412.22 KER20914.1 - 2.6e-24 85.2 26.7 6.7e-12 45.5 9.8 2.5 2 0 0 2 2 2 2 LIM domain Tetraspanin PF00335.20 KER20915.1 - 1.3e-43 149.4 8.2 1.5e-43 149.1 8.2 1.1 1 0 0 1 1 1 1 Tetraspanin family FERM_M PF00373.18 KER20918.1 - 2.1e-18 66.9 0.0 3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 FERM central domain Trypsin PF00089.26 KER20919.1 - 1.5e-07 31.5 1.0 2.4e-07 30.8 1.0 1.3 1 0 0 1 1 1 1 Trypsin Serpin PF00079.20 KER20920.1 - 3.1e-55 188.0 0.0 3.4e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Trypsin PF00089.26 KER20921.1 - 4.6e-09 36.4 0.0 0.0018 18.1 0.0 2.1 1 1 1 2 2 2 2 Trypsin YecM PF06185.12 KER20921.1 - 0.00011 22.0 0.4 0.54 9.9 0.0 2.4 2 0 0 2 2 2 2 YecM protein Serpin PF00079.20 KER20922.1 - 9.8e-09 35.0 0.3 5.6e-07 29.2 0.2 2.1 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) Sigma54_DBD PF04552.13 KER20922.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Serpin PF00079.20 KER20923.1 - 5.5e-10 39.1 0.3 1.4e-09 37.7 0.3 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) Trypsin PF00089.26 KER20924.1 - 4.6e-07 29.9 0.0 5.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin YecM PF06185.12 KER20924.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 YecM protein Serpin PF00079.20 KER20925.1 - 3.6e-59 200.9 0.0 4.5e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Trypsin PF00089.26 KER20926.1 - 0.00015 21.6 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin Serpin PF00079.20 KER20927.1 - 2.3e-30 106.2 0.0 2.9e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Methyltr_RsmB-F PF01189.17 KER20928.1 - 1.2e-20 74.1 0.9 1.8e-12 47.4 0.0 3.9 5 0 0 5 5 5 3 16S rRNA methyltransferase RsmB/F tRNA_m1G_MT PF01746.21 KER20928.1 - 2.7e-12 46.8 0.0 1.4e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RVT_1 PF00078.27 KER20928.1 - 2e-05 24.2 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_31 PF13847.6 KER20928.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KER20928.1 - 0.036 14.2 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase ArfGap PF01412.18 KER20929.1 - 8.1e-31 106.5 0.0 2.7e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KER20929.1 - 2.8e-16 59.9 5.8 2.8e-16 59.9 5.8 1.6 2 0 0 2 2 2 1 BAR domain of APPL family Ank_2 PF12796.7 KER20929.1 - 2.3e-12 47.3 0.2 6.3e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) SH3_1 PF00018.28 KER20929.1 - 8.1e-12 44.6 0.1 8.1e-12 44.6 0.1 1.9 2 0 0 2 2 1 1 SH3 domain PH PF00169.29 KER20929.1 - 5.5e-11 42.9 0.1 1.8e-10 41.2 0.0 2.0 2 0 0 2 2 1 1 PH domain SH3_9 PF14604.6 KER20929.1 - 1.5e-10 40.7 0.1 3.7e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER20929.1 - 8.6e-09 35.0 0.0 1.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 KER20929.1 - 4.8e-08 33.1 0.0 1.2e-05 25.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER20929.1 - 7.5e-08 32.8 0.2 3.4e-07 30.7 0.2 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER20929.1 - 2.6e-05 24.2 0.1 0.0043 17.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KER20929.1 - 3.1e-05 24.2 0.5 0.0058 17.0 0.2 3.1 2 0 0 2 2 2 1 Ankyrin repeat IMD PF08397.11 KER20929.1 - 3.8e-05 23.2 1.8 0.00011 21.6 1.0 2.1 2 0 0 2 2 2 1 IRSp53/MIM homology domain BAR PF03114.18 KER20929.1 - 0.00047 19.9 3.6 0.00078 19.2 3.6 1.3 1 0 0 1 1 1 1 BAR domain PH_9 PF15410.6 KER20929.1 - 0.0063 16.9 0.1 0.03 14.7 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain REC1 PF18501.1 KER20929.1 - 0.018 15.0 1.0 0.035 14.0 1.0 1.5 1 0 0 1 1 1 0 Alpha helical recognition lobe domain PH_11 PF15413.6 KER20929.1 - 0.031 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain BAG PF02179.16 KER20931.1 - 1.7e-12 47.6 3.8 2.8e-12 46.9 3.8 1.3 1 0 0 1 1 1 1 BAG domain ZapB PF06005.12 KER20931.1 - 0.16 12.5 0.8 46 4.5 0.1 3.2 2 1 1 3 3 3 0 Cell division protein ZapB DUF2682 PF10909.8 KER20931.1 - 0.23 12.0 0.1 0.63 10.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2682) Mito_carr PF00153.27 KER20932.1 - 1.4e-43 146.7 1.8 5.7e-16 58.2 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein GAS PF13851.6 KER20933.1 - 3.2e-52 176.8 24.9 1.5e-29 102.8 13.1 4.5 2 2 2 4 4 4 2 Growth-arrest specific micro-tubule binding Metal_resist PF13801.6 KER20933.1 - 0.041 14.1 0.6 0.041 14.1 0.6 4.2 4 1 0 4 4 4 0 Heavy-metal resistance Virulence_fact PF13769.6 KER20933.1 - 0.049 13.9 0.3 0.049 13.9 0.3 3.2 2 1 0 3 3 3 0 Virulence factor DUF4224 PF13986.6 KER20933.1 - 0.12 12.3 0.0 0.46 10.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF4726 PF15855.5 KER20933.1 - 8.4 6.7 5.6 64 3.8 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) Dynein_light PF01221.18 KER20934.1 - 1.1e-17 64.1 0.0 2.5e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 RVT_1 PF00078.27 KER20934.1 - 0.001 18.6 0.0 0.0045 16.5 0.0 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_light PF01221.18 KER20935.1 - 1.3e-16 60.7 0.0 2.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 G-gamma PF00631.22 KER20935.1 - 0.12 12.4 0.0 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 GGL domain AT_hook PF02178.19 KER20936.1 - 2.7 8.2 6.7 7.1 6.9 6.7 1.8 1 0 0 1 1 1 0 AT hook motif ANAPC4_WD40 PF12894.7 KER20940.1 - 3.9e-22 78.4 0.7 0.0027 18.0 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER20940.1 - 1.2e-19 70.2 5.8 4.5e-06 27.3 0.1 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 KER20940.1 - 3e-07 30.5 0.0 0.0099 15.8 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.6 KER20940.1 - 0.012 14.9 0.0 0.037 13.3 0.0 1.7 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 SnoaL_3 PF13474.6 KER20940.1 - 0.013 15.8 0.0 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 SnoaL-like domain IKI3 PF04762.12 KER20940.1 - 0.03 12.4 0.0 0.37 8.7 0.0 2.4 2 1 1 3 3 3 0 IKI3 family Cytochrom_D1 PF02239.16 KER20940.1 - 0.17 10.4 0.0 1.5 7.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Phos_pyr_kin PF08543.12 KER20942.1 - 6.4e-09 35.5 0.0 2.8e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KER20942.1 - 5.5e-07 29.2 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MORN PF02493.20 KER20943.1 - 7.7e-23 79.0 27.6 6e-05 22.7 3.5 7.7 7 1 0 7 7 7 6 MORN repeat G-gamma PF00631.22 KER20946.1 - 1.2e-15 57.2 0.1 1.4e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 GGL domain RHH_1 PF01402.21 KER20946.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family RVT_1 PF00078.27 KER20947.1 - 3.9e-07 29.8 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4629 PF15442.6 KER20947.1 - 4.1 7.6 10.5 8.7 6.6 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Tr-sialidase_C PF11052.8 KER20949.1 - 7.9 6.7 9.2 22 5.3 1.3 2.6 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal DUF2052 PF09747.9 KER20951.1 - 3.9e-14 53.3 14.0 1.5e-10 41.5 0.4 3.4 2 2 2 4 4 4 2 Coiled-coil domain containing protein (DUF2052) Fe_dep_repress PF01325.19 KER20951.1 - 0.067 13.4 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF4187 PF13821.6 KER20952.1 - 1.7e-16 59.7 1.8 5.2e-16 58.2 1.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KER20952.1 - 2.2e-13 49.8 1.7 5.4e-13 48.6 1.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KER20952.1 - 0.00042 20.3 0.8 0.00042 20.3 0.8 2.0 2 0 0 2 2 2 1 G-patch domain Ribosomal_L28e PF01778.17 KER20953.1 - 2.6e-19 70.1 0.4 3.1e-19 69.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family AAA PF00004.29 KER20954.1 - 1.6e-40 138.6 0.0 5.3e-40 136.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER20954.1 - 1.1e-08 34.7 0.1 2.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KER20954.1 - 7.5e-05 23.0 0.1 0.006 16.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KER20954.1 - 0.00016 21.7 0.0 0.00082 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KER20954.1 - 0.00022 21.4 0.0 0.00062 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KER20954.1 - 0.00054 20.4 0.2 0.023 15.1 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KER20954.1 - 0.0015 17.7 0.0 0.0036 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KER20954.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KER20954.1 - 0.0068 17.0 0.0 0.047 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KER20954.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KER20954.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KER20954.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KER20954.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KER20954.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KER20954.1 - 0.069 12.9 0.1 0.9 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 KER20954.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KER20954.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KER20954.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KER20954.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Prot_ATP_ID_OB PF16450.5 KER20954.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Sigma54_activat PF00158.26 KER20954.1 - 0.17 11.5 0.0 0.48 10.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Glyco_transf_43 PF03360.16 KER20955.1 - 3.4e-65 219.7 0.0 4.2e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 BCS1_N PF08740.11 KER20956.1 - 2.1e-40 138.7 0.6 3.6e-40 138.0 0.6 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KER20956.1 - 3.4e-21 76.1 0.0 6.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KER20956.1 - 0.00082 19.0 0.0 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KER20956.1 - 0.0012 19.3 0.0 0.0031 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 KER20956.1 - 0.0024 17.9 0.0 0.0089 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KER20956.1 - 0.0024 18.2 0.0 0.0047 17.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KER20956.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KER20956.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 KER20956.1 - 0.048 13.4 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER20956.1 - 0.052 14.1 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KER20956.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KER20956.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 KER20956.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KER20956.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER20956.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KER20956.1 - 0.15 12.4 0.0 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KER20956.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Snf7 PF03357.21 KER20957.1 - 5.8e-31 107.4 4.5 5.8e-31 107.4 4.5 1.3 2 0 0 2 2 2 1 Snf7 OKR_DC_1_C PF03711.15 KER20957.1 - 0.043 14.1 0.1 0.09 13.1 0.1 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain DUF2250 PF10007.9 KER20957.1 - 0.1 12.7 1.1 3.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DASH_Dam1 PF08653.10 KER20957.1 - 0.21 11.4 1.5 0.39 10.6 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Cytochrom_B562 PF07361.11 KER20957.1 - 3.4 8.4 11.9 0.66 10.7 0.2 3.0 3 0 0 3 3 3 0 Cytochrome b562 Peptidase_M22 PF00814.25 KER20959.1 - 1.1e-87 294.1 0.0 1.8e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family XPG_I_2 PF12813.7 KER20959.1 - 7.7e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 KER20959.1 - 3.5e-05 24.2 0.0 7.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KER20959.1 - 0.013 15.8 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 XPG I-region Eaf7 PF07904.13 KER20961.1 - 3.3e-17 62.8 0.1 6.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 TAF8_C PF10406.9 KER20963.1 - 7.4e-14 52.0 0.9 1.7e-13 50.9 0.9 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KER20963.1 - 2.7e-07 30.5 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated MORN PF02493.20 KER20964.1 - 6.3e-11 41.5 10.6 6.3e-09 35.2 3.1 2.6 2 0 0 2 2 2 2 MORN repeat Pdase_C33_assoc PF14756.6 KER20964.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase_C33-associated domain Cdc13_OB2 PF18691.1 KER20964.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain MORN PF02493.20 KER20965.1 - 2.1e-13 49.3 14.8 4.4e-06 26.3 0.8 3.5 3 0 0 3 3 3 3 MORN repeat DUF1419 PF07215.11 KER20965.1 - 0.12 12.4 1.2 7.1 6.8 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1419) MORN PF02493.20 KER20966.1 - 8.4e-17 60.0 25.1 3e-05 23.7 0.3 4.7 5 0 0 5 5 5 4 MORN repeat Enterotoxin_b PF01376.18 KER20966.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain TAF1_subA PF14929.6 KER20968.1 - 4.7e-15 55.9 0.6 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 TAF RNA Polymerase I subunit A Exo_endo_phos_2 PF14529.6 KER20968.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Otopetrin PF03189.13 KER20970.1 - 6.5e-32 110.9 31.2 1e-21 77.3 20.4 3.4 1 1 1 2 2 2 2 Otopetrin DUF5134 PF17197.4 KER20970.1 - 0.56 10.1 6.2 0.47 10.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) Carn_acyltransf PF00755.20 KER20972.1 - 2.7e-180 600.9 0.0 3.1e-180 600.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cpn60_TCP1 PF00118.24 KER20974.1 - 5.7e-148 493.6 8.6 6.7e-148 493.4 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4837 PF16125.5 KER20975.1 - 0.048 12.7 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Pkinase PF00069.25 KER20976.1 - 2.3e-66 223.8 0.0 2.9e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER20976.1 - 3.7e-34 118.2 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER20976.1 - 4.8e-06 26.1 0.0 0.00027 20.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KER20976.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KER20976.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DAGK_cat PF00781.24 KER20979.1 - 4.6e-08 32.7 0.0 1.5e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 KER20979.1 - 2.3e-06 26.6 0.0 3.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 WD40 PF00400.32 KER20983.1 - 4.3e-50 166.6 25.7 5.3e-08 33.4 0.0 9.3 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER20983.1 - 5.7e-15 55.4 2.4 0.052 13.8 0.0 6.0 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KER20983.1 - 3.2e-09 37.2 0.1 5.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 KER20983.1 - 4.7e-08 32.4 0.0 0.047 12.6 0.0 4.6 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KER20983.1 - 2.3e-05 23.3 0.6 1.4 7.5 0.0 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 KER20983.1 - 0.024 14.6 3.1 8.1 6.5 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KER20983.1 - 0.027 14.3 0.0 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 KER20983.1 - 8.1 6.3 7.4 45 3.9 0.6 3.9 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Isochorismatase PF00857.20 KER20984.1 - 2.5e-25 89.7 0.4 1.1e-24 87.6 0.4 1.9 1 1 0 1 1 1 1 Isochorismatase family SH3_9 PF14604.6 KER20985.1 - 1.4e-18 66.5 1.4 2.7e-11 43.1 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.24 KER20985.1 - 3.2e-17 62.4 0.0 7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 KER20985.1 - 1.2e-08 34.5 0.2 0.0015 18.2 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KER20985.1 - 3.1e-08 33.1 0.3 1.5e-06 27.7 0.0 2.9 3 0 0 3 3 3 1 SH3 domain His_Me_b4a2 PF18275.1 KER20986.1 - 0.096 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain ABC_membrane PF00664.23 KER20986.1 - 0.88 9.2 7.3 0.74 9.4 1.6 2.3 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF2207 PF09972.9 KER20986.1 - 1.5 7.5 8.0 4.1 6.1 1.8 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DP PF08781.10 KER20987.1 - 1.1e-36 125.8 2.1 1.4e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor DP E2F_TDP PF02319.20 KER20987.1 - 1.2e-18 66.9 1.4 1.3e-18 66.8 0.2 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Tyr-DNA_phospho PF06087.12 KER20988.1 - 6.1e-114 381.2 0.0 7.9e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 KER20988.1 - 2.9e-12 46.3 8.1 7.7e-12 45.0 8.1 1.8 1 0 0 1 1 1 1 PBZ domain 7tm_1 PF00001.21 KER20989.1 - 2.5e-20 72.9 15.2 3.6e-20 72.4 15.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER20989.1 - 3.2e-14 52.9 19.5 2e-09 37.2 14.5 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Leu_zip PF15294.6 KER20990.1 - 0.0057 16.2 7.5 0.0057 16.2 7.5 3.5 1 1 3 4 4 4 2 Leucine zipper DUF2935 PF11155.8 KER20990.1 - 0.024 14.9 7.4 1.1 9.6 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DivIC PF04977.15 KER20990.1 - 0.036 13.8 0.4 0.036 13.8 0.4 6.6 5 2 2 7 7 7 0 Septum formation initiator Flagellin_N PF00669.20 KER20990.1 - 0.082 13.0 10.6 0.23 11.6 2.8 3.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region BRI3BP PF14965.6 KER20990.1 - 1.5 8.3 4.5 3 7.3 0.3 3.1 2 1 1 3 3 3 0 Negative regulator of p53/TP53 DUF4164 PF13747.6 KER20990.1 - 3 8.2 45.3 0.35 11.2 9.1 7.1 1 1 6 8 8 8 0 Domain of unknown function (DUF4164) CLZ PF16526.5 KER20990.1 - 6.4 7.2 39.7 0.089 13.2 3.6 7.5 4 1 5 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pkinase PF00069.25 KER20991.1 - 7.6e-41 140.2 0.0 3.5e-13 49.5 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KER20991.1 - 1.5e-30 106.3 0.0 1.1e-08 34.7 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Mst1_SARAH PF11629.8 KER20991.1 - 1.8e-17 63.1 0.3 4.7e-17 61.8 0.3 1.8 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Cdd1 PF11731.8 KER20991.1 - 0.052 13.8 0.0 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Pathogenicity locus DJ-1_PfpI PF01965.24 KER20992.1 - 8.6e-41 139.5 0.0 1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KER20992.1 - 0.0036 17.0 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KER20992.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DSL PF01414.19 KER20994.1 - 1.3e-11 44.5 1.9 1.3e-11 44.5 1.9 4.1 4 0 0 4 4 4 1 Delta serrate ligand EGF PF00008.27 KER20994.1 - 5.5e-06 26.6 13.4 0.00036 20.8 4.8 5.6 6 0 0 6 6 6 3 EGF-like domain hEGF PF12661.7 KER20994.1 - 0.00011 22.7 36.3 0.0069 17.0 0.4 5.5 5 0 0 5 5 4 3 Human growth factor-like EGF EGF_CA PF07645.15 KER20994.1 - 0.0021 18.2 7.8 0.0021 18.2 7.8 5.4 3 2 2 5 5 5 2 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 KER20994.1 - 0.0058 16.9 18.3 0.22 11.8 5.1 4.1 3 1 1 4 4 4 2 Pvs28 EGF domain Orthoreo_P10 PF07204.11 KER20994.1 - 0.032 14.2 0.3 0.057 13.4 0.3 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 CD225 PF04505.12 KER20994.1 - 0.14 12.3 0.7 0.35 11.1 0.1 2.0 1 1 1 2 2 2 0 Interferon-induced transmembrane protein DUF4381 PF14316.6 KER20994.1 - 0.34 11.2 0.7 0.57 10.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EGF_3 PF12947.7 KER20994.1 - 3.1 8.1 25.7 0.4 10.9 3.8 4.0 3 0 0 3 3 3 0 EGF domain EGF_2 PF07974.13 KER20994.1 - 5.6 7.4 45.3 0.16 12.4 1.6 5.7 5 0 0 5 5 5 0 EGF-like domain cEGF PF12662.7 KER20994.1 - 6.9 6.7 16.4 0.16 11.9 1.6 3.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like PurA PF04845.13 KER20998.1 - 3.1e-94 314.4 0.2 4.3e-94 313.9 0.2 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein RVT_1 PF00078.27 KER20998.1 - 5.2e-07 29.4 0.0 1.5e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3276 PF11680.8 KER20998.1 - 1.1e-06 28.8 0.7 0.21 11.7 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) EFG_C PF00679.24 KER20998.1 - 0.02 14.9 0.1 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Elongation factor G C-terminus HARE-HTH PF05066.13 KER20998.1 - 0.049 14.0 0.1 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Actin PF00022.19 KER21000.1 - 9.4e-19 67.3 0.0 7.8e-10 37.9 0.0 2.7 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KER21000.1 - 1.2e-10 41.2 0.3 3.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family Hormone_3 PF00159.18 KER21000.1 - 0.051 13.7 0.2 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide Ribosomal_L7Ae PF01248.26 KER21002.1 - 9.6e-28 95.8 0.1 1.3e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KER21002.1 - 4.7e-05 23.5 0.0 6.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KER21002.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain ChitinaseA_N PF08329.10 KER21002.1 - 0.0049 16.5 0.2 0.59 9.8 0.0 2.7 3 0 0 3 3 3 1 Chitinase A, N-terminal domain Ank_2 PF12796.7 KER21003.1 - 1e-05 26.0 0.0 0.00044 20.8 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER21003.1 - 1.2e-05 25.7 0.0 0.12 13.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER21003.1 - 3.8e-05 23.9 0.0 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21003.1 - 0.00028 21.1 0.2 0.046 14.3 0.0 4.6 6 0 0 6 6 6 1 Ankyrin repeat SOCS_box PF07525.16 KER21003.1 - 1.6 9.2 4.5 0.41 11.0 0.6 2.2 2 0 0 2 2 2 0 SOCS box ODC_AZ PF02100.17 KER21004.1 - 7.9e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme 7tm_1 PF00001.21 KER21006.1 - 1.2e-15 57.6 0.1 1.3e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CZB PF13682.6 KER21007.1 - 0.068 13.6 0.1 0.081 13.4 0.1 1.2 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain AD PF09793.9 KER21009.1 - 2.4e-17 62.8 0.2 4.2e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain CENP-F_leu_zip PF10473.9 KER21012.1 - 0.0039 17.2 10.2 0.0039 17.2 10.2 8.1 3 2 4 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Stap_Strp_tox_C PF02876.17 KER21012.1 - 0.02 15.2 0.1 0.1 12.9 0.1 2.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Roc PF08477.13 KER21013.1 - 1.2e-14 54.6 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER21013.1 - 1.3e-12 47.6 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KER21013.1 - 3.7e-05 23.3 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER21013.1 - 0.00057 19.4 0.0 0.0034 16.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KER21013.1 - 0.0007 19.7 0.0 0.001 19.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER21013.1 - 0.0055 16.2 0.1 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.6 KER21013.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KER21013.1 - 0.022 15.1 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KER21013.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KER21013.1 - 0.046 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KER21013.1 - 0.07 12.3 0.3 1.3 8.1 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 KER21013.1 - 0.12 12.8 0.0 0.58 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KER21013.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER21013.1 - 0.16 12.4 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter zf-Di19 PF05605.12 KER21016.1 - 4.9e-05 23.5 21.4 0.0011 19.2 0.2 4.5 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KER21016.1 - 0.00014 22.4 49.4 0.0042 17.8 0.8 7.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-met PF12874.7 KER21016.1 - 0.0004 20.7 1.5 0.0004 20.7 1.5 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KER21016.1 - 0.00055 20.2 16.8 0.041 14.2 0.5 3.7 4 0 0 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KER21016.1 - 0.0025 18.0 0.8 0.0025 18.0 0.8 4.5 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KER21016.1 - 0.0048 17.3 9.6 0.014 15.8 2.3 7.1 7 0 0 7 7 6 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KER21016.1 - 0.0096 15.7 0.0 0.0096 15.7 0.0 4.9 4 1 0 4 4 4 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KER21016.1 - 0.036 14.5 0.7 0.036 14.5 0.7 6.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KER21016.1 - 0.43 11.3 7.2 12 6.6 0.0 3.7 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KER21016.1 - 1.1 9.0 9.3 0.067 12.8 1.2 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KER21016.1 - 2.3 8.2 6.7 16 5.4 0.2 4.1 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KER21016.1 - 7.7 6.2 14.3 12 5.6 0.1 4.3 4 0 0 4 4 4 0 MYST family zinc finger domain CpXC PF14353.6 KER21016.1 - 9.2 6.3 8.2 4 7.5 0.4 3.1 3 1 0 3 3 3 0 CpXC protein zf-UBR PF02207.20 KER21018.1 - 5.1e-16 58.6 5.5 5.1e-16 58.6 5.5 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 KER21018.1 - 0.00046 20.5 1.1 0.00046 20.5 1.1 4.6 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 KER21018.1 - 0.00047 19.9 0.6 0.00047 19.9 0.6 3.8 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KER21018.1 - 0.0072 16.3 0.2 0.045 13.8 0.2 2.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER21018.1 - 0.054 13.4 0.1 0.054 13.4 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER21018.1 - 0.2 11.6 0.0 0.2 11.6 0.0 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) MIEAP PF16026.5 KER21020.1 - 2.2e-36 126.0 0.1 2.7e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Mitochondria-eating protein Syntaxin PF00804.25 KER21020.1 - 0.0028 17.3 0.3 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Syntaxin TipAS PF07739.13 KER21020.1 - 0.15 12.6 0.2 0.36 11.4 0.0 1.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain zf-met PF12874.7 KER21022.1 - 0.019 15.4 1.0 1.5 9.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER21022.1 - 0.063 14.1 13.2 0.51 11.3 1.1 3.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KER21022.1 - 0.086 13.3 16.0 0.38 11.3 3.2 3.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KER21022.1 - 2.2 8.7 5.1 3.4 8.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER21022.1 - 4.5 7.4 11.6 5 7.2 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KER21023.1 - 3.8e-06 27.3 5.3 0.0095 16.7 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KER21023.1 - 7.9e-05 22.9 5.9 0.045 14.2 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KER21023.1 - 0.0003 21.1 0.4 0.0003 21.1 0.4 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf_UBZ PF18439.1 KER21023.1 - 0.014 15.0 0.9 0.091 12.4 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KER21023.1 - 0.014 15.3 2.3 0.15 12.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CEBP_ZZ PF16366.5 KER21023.1 - 0.056 13.7 5.7 0.14 12.4 5.7 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C2H2_jaz PF12171.8 KER21023.1 - 0.092 13.1 2.5 1.2 9.5 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HECT PF00632.25 KER21024.1 - 8.8e-73 245.5 0.0 1.7e-72 244.5 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RseA_C PF03873.13 KER21024.1 - 0.27 11.5 3.4 3.1 8.1 0.5 3.6 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain UVR PF02151.19 KER21031.1 - 1.6e-09 37.2 13.8 8.4e-07 28.5 0.7 2.8 3 0 0 3 3 3 2 UvrB/uvrC motif zf_UBZ PF18439.1 KER21031.1 - 0.56 9.9 6.0 3.7 7.2 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KER21031.1 - 1.4 9.0 9.5 6 7.0 0.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon Com_YlbF PF06133.11 KER21031.1 - 1.9 9.1 7.6 0.14 12.8 1.9 1.9 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Epiglycanin_C PF14654.6 KER21034.1 - 0.048 13.7 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Ion_trans PF00520.31 KER21036.1 - 8.3e-25 87.4 1.8 3.9e-24 85.2 1.8 1.9 1 1 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KER21037.1 - 3.8e-109 363.6 43.0 7.5e-59 198.9 15.2 4.6 4 1 1 5 5 5 4 Ion transport protein GPHH PF16905.5 KER21037.1 - 1.2e-30 105.1 0.1 2.4e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 KER21037.1 - 2.7e-16 59.5 0.3 6.1e-16 58.4 0.3 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 KER21037.1 - 3.5e-06 26.0 16.1 3.5e-06 26.0 16.1 4.4 4 1 0 4 4 4 3 Polycystin cation channel Helicase_C PF00271.31 KER21038.1 - 4.9e-07 30.1 0.3 1e-06 29.1 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER21039.1 - 5.1e-48 163.2 0.0 1.2e-47 161.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER21039.1 - 2.8e-07 30.9 0.0 0.00015 22.1 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KER21039.1 - 0.00024 21.1 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 KER21040.1 - 4.6e-05 23.3 36.3 0.22 11.7 0.9 5.6 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 KER21040.1 - 3.6 7.6 34.5 3.2 7.8 11.6 4.7 2 1 1 3 3 3 0 Zinc knuckle zf-C4 PF00105.18 KER21043.1 - 1.8e-07 31.5 12.8 2.6e-07 31.0 8.4 3.1 2 1 1 3 3 3 1 Zinc finger, C4 type (two domains) zf-CCHC PF00098.23 KER21043.1 - 0.00013 21.9 3.7 0.00013 21.9 3.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KER21043.1 - 0.66 9.7 8.0 0.14 11.9 3.6 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KER21043.1 - 1.1 9.1 10.6 0.13 12.1 5.9 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 KER21043.1 - 5.3 7.1 9.3 0.086 12.8 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle MORN PF02493.20 KER21044.1 - 3.1e-34 114.8 46.0 6.1e-05 22.7 2.3 10.0 9 0 0 9 9 9 8 MORN repeat GP46 PF07409.12 KER21044.1 - 0.26 11.0 2.5 85 2.9 0.0 3.5 3 0 0 3 3 3 0 Phage protein GP46 YtxH PF12732.7 KER21044.1 - 0.39 11.3 6.1 11 6.7 1.9 2.7 2 0 0 2 2 2 0 YtxH-like protein DUF1419 PF07215.11 KER21044.1 - 0.58 10.3 2.3 50 4.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1419) Ribosomal_L4 PF00573.22 KER21044.1 - 3.8 7.1 10.6 0.18 11.5 0.9 2.9 3 0 0 3 3 3 0 Ribosomal protein L4/L1 family DUF883 PF05957.13 KER21044.1 - 6.8 7.4 13.8 30 5.3 7.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4600 PF15372.6 KER21045.1 - 0.074 13.5 1.1 19 5.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Innexin PF00876.18 KER21047.1 - 3.1e-102 342.5 5.0 3.6e-102 342.2 5.0 1.0 1 0 0 1 1 1 1 Innexin TssO PF17561.2 KER21047.1 - 0.3 11.2 0.7 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssO RolB_RolC PF02027.17 KER21049.1 - 0.029 14.1 0.7 0.064 12.9 0.7 1.6 1 1 0 1 1 1 0 RolB/RolC glucosidase family MerR_2 PF13591.6 KER21051.1 - 0.24 11.3 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein NOP5NT PF08156.13 KER21056.1 - 0.082 13.3 0.0 54 4.3 0.0 3.5 4 0 0 4 4 4 0 NOP5NT (NUC127) domain Trypsin PF00089.26 KER21057.1 - 1.8e-44 152.2 0.3 6e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KER21057.1 - 0.00016 22.6 0.0 0.00027 21.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 KER21057.1 - 0.00017 21.2 0.0 0.19 11.2 0.0 2.3 2 1 0 2 2 2 2 Chymotrypsin family Peptidase-S1 Peptidase_M1 PF01433.20 KER21058.1 - 4e-51 173.7 1.6 6.9e-51 172.9 1.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KER21058.1 - 4.9e-37 127.9 0.0 6.9e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain rve PF00665.26 KER21058.1 - 5.4e-11 42.7 0.0 3.2e-10 40.2 0.0 2.2 1 1 1 2 2 2 1 Integrase core domain rve_3 PF13683.6 KER21058.1 - 0.00026 20.7 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Aminopep PF10023.9 KER21058.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase Zincin_1 PF06262.11 KER21058.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase GCD14_N PF14801.6 KER21060.1 - 0.039 13.8 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DHHA2 PF02833.14 KER21061.1 - 2.8e-10 40.5 0.0 7.8e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 DHHA2 domain Complex1_LYR PF05347.15 KER21061.1 - 3.6e-08 33.3 0.1 9.6e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DHH PF01368.20 KER21061.1 - 0.0038 17.4 0.3 0.035 14.3 0.4 2.3 2 1 0 2 2 2 1 DHH family Asp PF00026.23 KER21064.1 - 9.7e-44 150.1 0.0 2e-43 149.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER21064.1 - 2e-13 51.0 0.0 1.8e-08 34.9 0.0 3.3 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER21064.1 - 0.00071 20.2 0.0 1.7 9.3 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease Glyoxalase_2 PF12681.7 KER21064.1 - 0.18 11.7 0.0 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain NIF PF03031.18 KER21067.1 - 1.4e-47 161.4 0.1 2.2e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ecl1 PF12855.7 KER21068.1 - 0.064 14.4 7.8 0.079 14.1 7.8 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins HA2 PF04408.23 KER21069.1 - 2e-13 50.6 0.0 4.8e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KER21069.1 - 1.6e-09 38.1 0.0 4.7e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER21069.1 - 2.9e-05 23.9 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KER21069.1 - 0.0016 18.8 0.1 0.005 17.2 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold zf-C4 PF00105.18 KER21071.1 - 9e-05 22.9 0.6 9e-05 22.9 0.6 1.1 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) CaKB PF03185.15 KER21073.1 - 0.0036 17.0 0.6 0.0044 16.7 0.6 1.1 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit Hormone_recep PF00104.30 KER21074.1 - 0.00051 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor eIF-3c_N PF05470.12 KER21075.1 - 0.029 12.7 0.6 0.027 12.8 0.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.12 KER21075.1 - 0.32 9.4 19.2 0.37 9.2 19.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Peptidase_S8 PF00082.22 KER21076.1 - 8.5e-32 110.6 0.0 1.5e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family MULE PF10551.9 KER21076.1 - 4.5e-18 65.5 0.0 1.1e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain DUF4350 PF14258.6 KER21076.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Peptidase_S8 PF00082.22 KER21077.1 - 2.5e-29 102.5 0.0 4.9e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Subtilase family DUF4350 PF14258.6 KER21077.1 - 0.015 15.7 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Potassium_chann PF11404.8 KER21081.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Potassium voltage-gated channel Ig_3 PF13927.6 KER21082.1 - 4e-13 49.8 1.1 6.6e-06 26.6 0.0 5.5 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KER21082.1 - 2.7e-09 37.0 0.2 0.0038 17.2 0.0 4.4 4 1 0 4 4 4 2 Immunoglobulin I-set domain ig PF00047.25 KER21082.1 - 1.1e-08 35.2 0.0 0.00019 21.5 0.0 3.9 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 KER21082.1 - 1.2e-08 35.1 1.2 0.0095 16.1 0.0 4.5 6 0 0 6 6 6 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KER21082.1 - 0.00012 22.3 0.9 1.4 9.3 0.0 5.9 6 1 0 6 6 6 1 Immunoglobulin domain Pox_ser-thr_kin PF05445.11 KER21084.1 - 0.052 12.5 0.0 0.057 12.4 0.0 1.0 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ssl1 PF04056.14 KER21086.1 - 1.5e-69 233.7 0.1 2.4e-69 233.0 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like Metallophos PF00149.28 KER21086.1 - 1.4e-35 123.7 0.0 2.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER21086.1 - 1.1e-13 51.3 0.0 2.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain VWA_2 PF13519.6 KER21086.1 - 2.1e-12 47.6 0.0 8.3e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain MRF_C1 PF13887.6 KER21086.1 - 0.098 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DHHC PF01529.20 KER21088.1 - 1.1e-32 112.9 11.5 1.1e-32 112.9 11.5 2.9 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KER21088.1 - 5.1e-26 90.7 4.4 3.8e-09 36.9 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER21088.1 - 1.6e-23 83.1 0.0 2.3e-13 50.5 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER21088.1 - 1.6e-23 82.4 6.5 1.1e-06 28.8 0.2 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21088.1 - 2.5e-22 76.6 4.6 0.00023 21.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KER21088.1 - 1.8e-18 66.1 6.4 6.8e-07 29.5 0.3 5.7 5 0 0 5 5 5 4 Ankyrin repeat DHHC PF01529.20 KER21090.1 - 8.1e-31 106.9 20.0 8.1e-31 106.9 20.0 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KER21090.1 - 2.4e-11 43.9 1.0 0.00016 22.2 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER21090.1 - 6.5e-11 42.7 0.1 1.5e-08 35.1 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER21090.1 - 1.1e-10 41.5 4.5 1.2e-05 25.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21090.1 - 7.3e-09 35.2 0.3 0.003 17.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KER21090.1 - 2e-06 28.0 0.3 0.00026 21.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Pyridoxal_deC PF00282.19 KER21091.1 - 6e-26 91.0 0.1 7.1e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.19 KER21092.1 - 5.4e-28 97.8 0.1 5.5e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KER21092.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 KER21092.1 - 0.19 10.4 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Pyridoxal_deC PF00282.19 KER21093.1 - 8.6e-32 110.3 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RVT_1 PF00078.27 KER21093.1 - 1.6e-10 40.9 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR19-TM PF15176.6 KER21094.1 - 7.7 6.6 8.0 18 5.4 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Striatin PF08232.12 KER21095.1 - 1.2e-40 139.7 2.0 2.5e-40 138.6 2.0 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 KER21095.1 - 2.4e-20 72.5 7.9 0.0022 18.8 0.3 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER21095.1 - 0.00051 20.3 0.0 4.9 7.5 0.0 4.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PSP94 PF05825.11 KER21095.1 - 0.042 14.4 0.1 1.4 9.5 0.1 2.7 2 0 0 2 2 2 0 Beta-microseminoprotein (PSP-94) DUF4482 PF14818.6 KER21095.1 - 0.86 10.5 3.1 2.3 9.1 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) UBX PF00789.20 KER21096.1 - 4.1e-07 30.1 0.0 1.5e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 UBX domain OST3_OST6 PF04756.13 KER21096.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family PIN_8 PF18476.1 KER21096.1 - 0.62 9.9 6.2 1.2 8.9 6.2 1.5 1 0 0 1 1 1 0 PIN like domain DUF2894 PF11445.8 KER21096.1 - 1.9 8.9 11.8 2.5 8.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) TAP_C PF03943.13 KER21100.1 - 2.1e-18 65.7 0.2 2.9e-18 65.2 0.2 1.2 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 KER21100.1 - 0.035 13.9 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain LRR_8 PF13855.6 KER21101.1 - 0.01 15.5 0.5 0.28 11.0 1.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat Dus PF01207.17 KER21102.1 - 7.3e-42 143.5 0.2 3.1e-40 138.2 0.2 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 KER21102.1 - 7.8e-07 29.7 0.1 1.5e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif NMO PF03060.15 KER21102.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KER21102.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Pkinase_Tyr PF07714.17 KER21103.1 - 8.8e-86 287.4 0.0 1.2e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER21103.1 - 6.3e-44 150.3 0.0 1e-43 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER21103.1 - 1.5e-35 121.2 2.5 8e-18 64.3 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Haspin_kinase PF12330.8 KER21103.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Clathrin_lg_ch PF01086.17 KER21105.1 - 1.3e-20 74.5 0.1 1.5e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Clathrin light chain DGCR6 PF07324.11 KER21106.1 - 3.1e-40 137.9 5.5 3.9e-40 137.6 5.5 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein NPA PF16469.5 KER21106.1 - 0.13 12.9 1.8 0.87 10.2 0.1 2.2 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 Phosducin PF02114.16 KER21106.1 - 0.18 10.7 2.1 0.24 10.3 2.1 1.2 1 0 0 1 1 1 0 Phosducin Kazal_2 PF07648.15 KER21107.1 - 3.5e-13 49.4 18.1 4.3e-07 30.0 0.3 5.0 5 1 1 6 6 6 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KER21107.1 - 2.4e-09 37.1 23.6 3.8e-05 23.6 0.4 4.9 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain FOLN PF09289.10 KER21107.1 - 1.7e-05 24.9 13.0 3e-05 24.1 5.0 3.3 2 0 0 2 2 2 2 Follistatin/Osteonectin-like EGF domain Pkinase PF00069.25 KER21108.1 - 1.8e-58 198.0 0.0 4e-58 196.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 KER21108.1 - 8e-36 122.0 0.1 7.5e-17 61.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 KER21108.1 - 3.5e-29 101.9 0.0 1.2e-28 100.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER21108.1 - 0.0053 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FAM76 PF16046.5 KER21108.1 - 0.012 15.0 4.7 0.024 14.0 4.7 1.5 1 0 0 1 1 1 0 FAM76 protein APH PF01636.23 KER21108.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C13 PF01650.18 KER21111.1 - 1.8e-57 194.8 6.8 4.9e-37 127.8 2.0 2.1 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C13 PF01650.18 KER21112.1 - 2.3e-93 312.4 2.8 3.3e-93 311.9 2.8 1.2 1 0 0 1 1 1 1 Peptidase C13 family Sulfotransfer_3 PF13469.6 KER21112.1 - 0.029 14.8 0.2 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase family AgrB PF04647.15 KER21114.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Microvir_lysis PF04517.12 KER21115.1 - 0.029 14.3 1.2 5.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus E1_DerP2_DerF2 PF02221.15 KER21115.1 - 0.035 14.6 1.5 2.9 8.3 0.8 2.7 2 1 0 2 2 2 0 ML domain Peptidase_C13 PF01650.18 KER21116.1 - 1.1e-64 218.5 1.2 1.6e-63 214.6 1.2 2.0 1 1 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER21116.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Caspase domain HlyU PF10115.9 KER21117.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator HlyU RANK_CRD_2 PF18278.1 KER21118.1 - 0.0023 18.1 0.1 0.0023 18.1 0.1 2.0 1 1 1 2 2 2 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 CN_hydrolase PF00795.22 KER21121.1 - 2.8e-51 174.4 0.0 3.7e-36 124.8 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase RRM_1 PF00076.22 KER21122.1 - 9.7e-44 147.1 0.2 9.2e-11 41.4 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER21122.1 - 1.8e-10 40.5 0.0 0.0035 16.9 0.1 4.0 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KER21122.1 - 1e-05 25.4 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 KER21122.1 - 0.00043 20.1 0.0 0.31 10.9 0.0 3.8 4 1 0 4 4 4 1 Occluded RNA-recognition motif K_channel_TID PF07941.11 KER21122.1 - 0.011 16.1 5.8 0.011 16.1 5.8 3.6 3 1 1 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain DUF1866 PF08952.11 KER21122.1 - 0.042 13.7 0.0 33 4.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) RRM_Rrp7 PF17799.1 KER21122.1 - 0.049 13.4 0.7 32 4.3 0.2 3.5 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain RskA PF10099.9 KER21122.1 - 0.96 9.7 23.4 3.4 7.9 12.9 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Endotoxin_M PF00555.19 KER21123.1 - 0.077 13.0 0.1 0.087 12.9 0.1 1.1 1 0 0 1 1 1 0 delta endotoxin DSPc PF00782.20 KER21124.1 - 1.9e-14 53.6 0.1 2.7e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER21125.1 - 3.3e-51 174.1 0.0 5.3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Asp_protease_2 PF13650.6 KER21125.1 - 3.7e-05 24.3 0.5 0.0002 22.0 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease DSPc PF00782.20 KER21125.1 - 0.0033 17.2 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain gag-asp_proteas PF13975.6 KER21125.1 - 0.011 16.3 0.0 0.038 14.5 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 KER21125.1 - 0.015 15.6 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein PTPlike_phytase PF14566.6 KER21125.1 - 0.089 12.9 0.0 1.1 9.4 0.0 2.6 3 1 0 3 3 3 0 Inositol hexakisphosphate fn3 PF00041.21 KER21126.1 - 0.068 13.5 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 Fibronectin type III domain Nucleoporin_N PF08801.11 KER21128.1 - 7.8e-29 100.7 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like RVT_1 PF00078.27 KER21128.1 - 7.9e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PARP PF00644.20 KER21130.1 - 4.4e-60 202.6 0.0 7.1e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KER21130.1 - 3.2e-47 160.0 0.3 7.1e-47 158.9 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KER21130.1 - 4.5e-21 74.7 1.3 2e-20 72.6 0.5 2.3 1 1 1 2 2 2 1 WGR domain PADR1 PF08063.12 KER21130.1 - 1.5e-19 69.5 0.3 1.5e-19 69.5 0.3 2.2 3 0 0 3 3 3 1 PADR1 (NUC008) domain INSC_LBD PF16748.5 KER21131.1 - 0.023 14.1 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Inscuteable LGN-binding domain Mito_carr PF00153.27 KER21132.1 - 1.5e-17 63.3 0.5 2e-16 59.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein fn3 PF00041.21 KER21133.1 - 3.2e-06 27.4 0.0 5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_A22B PF04258.13 KER21133.1 - 0.071 12.6 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal peptide peptidase RINGv PF12906.7 KER21134.1 - 2.2e-14 53.3 9.6 4.5e-14 52.3 9.6 1.6 1 0 0 1 1 1 1 RING-variant domain SnAPC_2_like PF11035.8 KER21135.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.4 3 0 0 3 3 3 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb FXR_C1 PF16096.5 KER21135.1 - 0.11 12.7 1.3 0.24 11.6 1.3 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF1712 PF08217.11 KER21137.1 - 1.7e-26 92.9 0.2 5.2e-25 88.0 0.1 2.6 3 1 0 3 3 3 2 Fungal domain of unknown function (DUF1712) SPRY PF00622.28 KER21137.1 - 9.7e-13 48.3 0.0 1.7e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF4658 PF15555.6 KER21139.1 - 0.066 13.3 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Mito_carr PF00153.27 KER21140.1 - 1.3e-31 108.4 0.3 6.1e-12 45.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_1 PF00441.24 KER21142.1 - 1.7e-28 99.7 0.4 2.4e-28 99.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KER21142.1 - 1.1e-26 93.8 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KER21142.1 - 1.3e-17 63.8 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KER21142.1 - 2.1e-08 34.5 0.3 3.5e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Histone PF00125.24 KER21143.1 - 4.7e-12 46.4 0.7 7.1e-12 45.8 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KER21143.1 - 9e-06 26.3 1.4 1.3e-05 25.8 1.4 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain RVT_1 PF00078.27 KER21145.1 - 2.5e-05 23.9 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDUF_B8 PF05821.11 KER21145.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DHC_N1 PF08385.12 KER21146.1 - 2.2e-22 79.5 0.1 3e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Propep_M14 PF02244.16 KER21146.1 - 0.044 14.2 0.1 5.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Carboxypeptidase activation peptide RhoGEF PF00621.20 KER21147.1 - 6e-26 91.8 0.1 1.1e-25 91.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain Ig_2 PF13895.6 KER21150.1 - 0.0061 16.9 0.1 3.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set_2 PF15910.5 KER21150.1 - 0.099 12.7 0.2 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 ICOS V-set domain SUR7 PF06687.12 KER21151.1 - 0.026 14.2 7.7 0.052 13.2 7.7 1.5 1 0 0 1 1 1 0 SUR7/PalI family TssN PF17555.2 KER21151.1 - 0.93 8.8 4.0 1 8.7 4.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN GSG-1 PF07803.11 KER21151.1 - 1.6 8.7 4.4 2.7 7.9 0.3 2.4 2 1 0 2 2 2 0 GSG1-like protein CCDC23 PF15674.5 KER21154.1 - 0.00067 19.6 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 FXR_C1 PF16096.5 KER21154.1 - 0.06 13.5 2.8 0.12 12.6 2.8 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Dishevelled PF02377.15 KER21155.1 - 2.6e-38 132.0 14.3 2.6e-38 132.0 14.3 3.3 3 0 0 3 3 3 1 Dishevelled specific domain DIX PF00778.17 KER21155.1 - 2.6e-30 104.1 0.3 5.5e-30 103.0 0.3 1.6 1 0 0 1 1 1 1 DIX domain PDZ PF00595.24 KER21155.1 - 1.8e-18 66.7 0.7 3.1e-18 65.9 0.7 1.4 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 KER21155.1 - 5.1e-17 61.7 0.2 1.2e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 KER21155.1 - 2.2e-06 27.4 0.1 4.1e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER21155.1 - 0.0012 19.2 0.2 0.0022 18.3 0.2 1.4 1 0 0 1 1 1 1 PDZ domain HTH_IclR PF09339.10 KER21155.1 - 0.072 12.9 0.1 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain MBT PF02820.18 KER21156.1 - 6.2e-27 93.7 0.0 2.4e-20 72.6 0.0 2.6 2 0 0 2 2 2 2 mbt repeat RVT_1 PF00078.27 KER21156.1 - 4.7e-19 68.8 0.0 1.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_2 PF00002.24 KER21156.1 - 2.3e-10 40.2 21.7 3.7e-10 39.5 21.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 KER21156.1 - 0.007 16.9 0.4 0.018 15.5 0.4 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Membralin PF09746.9 KER21157.1 - 2e-105 353.0 6.9 3.2e-84 283.2 3.4 3.2 3 0 0 3 3 3 3 Tumour-associated protein HEAT PF02985.22 KER21158.1 - 2.4e-08 33.6 1.2 0.47 10.9 0.0 7.6 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KER21158.1 - 1.2e-06 28.7 3.9 1.4 8.9 0.1 5.3 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KER21158.1 - 0.0058 17.0 5.7 10 6.6 0.0 6.0 6 1 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 KER21158.1 - 0.0081 16.7 9.9 5.8 7.5 0.7 6.5 6 0 0 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KER21158.1 - 0.16 12.6 0.4 12 6.6 0.0 3.8 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region PPP4R2 PF09184.11 KER21158.1 - 0.94 9.0 2.5 6.7 6.2 0.1 2.2 2 0 0 2 2 2 0 PPP4R2 bZIP_1 PF00170.21 KER21160.1 - 1.4e-13 50.7 15.1 2.4e-13 49.9 15.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KER21160.1 - 6.6e-06 26.1 14.0 1.9e-05 24.7 13.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KER21160.1 - 0.00033 21.1 10.8 0.00064 20.2 10.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 KER21160.1 - 0.23 11.6 3.6 0.4 10.8 2.4 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4598 PF15370.6 KER21163.1 - 0.077 13.5 5.3 0.091 13.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) DUF4484 PF14831.6 KER21163.1 - 0.11 12.6 3.4 0.11 12.5 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RXT2_N PF08595.11 KER21163.1 - 0.24 11.4 6.8 0.29 11.2 6.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KER21163.1 - 0.62 9.3 15.4 0.63 9.3 15.4 1.1 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.11 KER21163.1 - 0.83 8.0 7.2 0.81 8.0 7.2 1.0 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 KER21163.1 - 2.1 7.4 19.7 2 7.5 19.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KER21163.1 - 2.9 5.9 15.0 2.8 5.9 15.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER21163.1 - 3.8 6.8 9.2 3.7 6.9 9.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KER21163.1 - 4 5.6 8.6 4.1 5.6 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KER21163.1 - 4.5 7.1 10.9 4.8 7.0 10.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region 7tm_1 PF00001.21 KER21164.1 - 3e-71 239.8 12.3 3.7e-71 239.5 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER21164.1 - 2.4e-09 37.2 14.9 2.4e-09 37.2 14.9 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER21164.1 - 9.6e-05 22.2 13.9 0.00041 20.2 11.3 2.1 2 0 0 2 2 2 1 Olfactory receptor DUF3671 PF12420.8 KER21164.1 - 0.94 9.6 5.4 8.2 6.5 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function MBD_C PF14048.6 KER21165.1 - 0.14 12.9 2.5 12 6.7 0.2 3.3 2 1 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 CDT1 PF08839.11 KER21167.1 - 1.1e-49 169.1 0.1 2.1e-49 168.2 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 KER21167.1 - 1.1e-16 61.0 0.1 2.9e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain EutC PF05985.11 KER21167.1 - 0.094 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) UQ_con PF00179.26 KER21173.1 - 4e-10 39.5 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KER21173.1 - 0.059 13.7 0.1 0.099 12.9 0.1 1.5 1 1 0 1 1 1 0 RWD domain ABC_tran PF00005.27 KER21174.1 - 1.4e-09 38.6 0.0 0.0013 19.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KER21174.1 - 0.00015 22.2 0.0 0.00039 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER21174.1 - 0.00045 20.5 0.0 0.0061 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KER21174.1 - 0.00073 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KER21174.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KER21174.1 - 0.014 15.2 0.9 0.39 10.4 0.0 2.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 KER21174.1 - 0.014 15.1 0.0 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KER21174.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5481 PF17578.2 KER21174.1 - 0.021 15.2 0.0 19 5.7 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5481) AAA PF00004.29 KER21174.1 - 0.025 15.0 0.0 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KER21174.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KER21174.1 - 0.032 13.9 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 KER21174.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3577 PF12101.8 KER21174.1 - 0.039 13.8 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Man-6-P_recep PF02157.15 KER21174.1 - 0.04 13.0 0.3 7.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Mannose-6-phosphate receptor AAA_29 PF13555.6 KER21174.1 - 0.042 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KER21174.1 - 0.1 12.6 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KER21174.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KER21174.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KER21174.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KER21174.1 - 0.23 10.8 0.0 0.56 9.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Kelch_1 PF01344.25 KER21175.1 - 1.2e-19 69.6 4.6 4.1e-07 29.5 0.3 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 KER21175.1 - 5e-10 39.3 5.9 0.0094 16.2 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KER21175.1 - 8.2e-09 35.3 1.7 1.5e-05 24.8 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KER21175.1 - 8.8e-09 35.4 2.7 0.0051 17.1 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KER21175.1 - 9e-09 35.2 1.7 0.038 14.0 0.0 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain BACK PF07707.15 KER21175.1 - 4.6e-05 23.5 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KER21175.1 - 0.012 15.5 1.5 7.9 6.6 0.1 3.7 3 0 0 3 3 3 0 Kelch motif DUF846 PF05832.12 KER21176.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Clat_adaptor_s PF01217.20 KER21177.1 - 3.2e-56 189.2 6.0 4.6e-56 188.7 6.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_22 PF13401.6 KER21177.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KER21178.1 - 0.00012 21.7 0.0 0.0086 15.6 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 KER21180.1 - 0.013 16.0 0.0 0.86 10.1 0.0 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Exo_endo_phos PF03372.23 KER21181.1 - 2.2e-12 47.0 0.0 2.7e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER21181.1 - 8.7e-07 28.8 0.0 1.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Abhydrolase_1 PF00561.20 KER21182.1 - 2.8e-19 69.8 0.1 7.4e-19 68.4 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER21182.1 - 1e-18 68.8 0.4 5e-18 66.5 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KER21182.1 - 6.6e-12 45.2 0.0 1.5e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KER21182.1 - 0.00068 19.6 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 KER21182.1 - 0.00096 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 KER21182.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 KER21182.1 - 0.0079 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF2974 PF11187.8 KER21182.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 KER21182.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KER21182.1 - 0.047 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme mTERF PF02536.14 KER21183.1 - 2e-19 69.7 0.2 8.9e-15 54.4 0.2 2.1 1 1 1 2 2 2 2 mTERF DUF1858 PF08984.11 KER21183.1 - 0.0046 17.1 0.0 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1858) TAL_effector PF03377.13 KER21183.1 - 0.086 13.2 0.0 5.8 7.3 0.0 2.7 3 0 0 3 3 3 0 TAL effector repeat Cyclin_N PF00134.23 KER21184.1 - 6.7e-21 74.4 2.1 1.4e-20 73.3 0.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER21184.1 - 0.0018 18.3 0.3 0.05 13.7 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain ASC PF00858.24 KER21185.1 - 8.5e-47 160.1 0.3 1.4e-46 159.5 0.3 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel EI24 PF07264.11 KER21185.1 - 0.009 16.3 0.7 3.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Peptidase_C50 PF03568.17 KER21186.1 - 6.4e-49 167.1 0.2 1.4e-43 149.5 0.0 2.6 1 1 0 2 2 2 2 Peptidase family C50 Peptidase_C13 PF01650.18 KER21190.1 - 7e-46 156.8 0.3 8.6e-46 156.5 0.3 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER21191.1 - 1.7e-86 289.9 1.2 2.4e-86 289.4 1.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER21191.1 - 0.034 14.1 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 Caspase domain Asp PF00026.23 KER21192.1 - 5.9e-05 22.6 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SCAMP PF04144.13 KER21194.1 - 2.1e-39 135.6 2.4 2.9e-39 135.2 2.4 1.1 1 0 0 1 1 1 1 SCAMP family RDD PF06271.12 KER21194.1 - 0.35 11.1 5.0 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 RDD family rve PF00665.26 KER21195.1 - 2.5e-19 69.6 0.0 4.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER21195.1 - 8.3e-07 28.7 0.1 2.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Branch PF02485.21 KER21196.1 - 1.9e-31 109.5 0.0 2.4e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme CYYR1 PF10873.8 KER21197.1 - 0.25 11.8 4.1 0.77 10.2 0.1 2.8 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TPK_catalytic PF04263.16 KER21201.1 - 0.0019 18.2 0.9 1.4 9.0 0.0 3.4 2 1 2 4 4 4 2 Thiamin pyrophosphokinase, catalytic domain FG-GAP PF01839.23 KER21201.1 - 0.072 13.2 6.7 0.085 13.0 1.0 3.1 3 0 0 3 3 3 0 FG-GAP repeat FG-GAP PF01839.23 KER21203.1 - 6.9e-16 58.1 4.6 2e-06 27.8 0.5 4.3 4 0 0 4 4 4 3 FG-GAP repeat Integrin_alpha2 PF08441.12 KER21203.1 - 3.6e-09 36.0 0.0 4.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha VCBS PF13517.6 KER21203.1 - 0.001 19.6 7.4 0.13 12.9 0.4 3.4 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 KER21203.1 - 0.16 11.3 0.1 18 4.6 0.0 2.6 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region rve PF00665.26 KER21207.1 - 0.018 15.2 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DIT1_PvcA PF05141.12 KER21208.1 - 0.012 15.0 1.8 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein LAMTOR5 PF16672.5 KER21208.1 - 0.095 12.6 0.4 3.9 7.5 0.0 2.4 1 1 1 2 2 2 0 Ragulator complex protein LAMTOR5 Myb_DNA-bind_7 PF15963.5 KER21209.1 - 9.3e-25 86.4 0.8 1.6e-24 85.6 0.2 1.7 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KER21209.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAC1 PF16094.5 KER21209.1 - 0.44 9.7 1.8 0.87 8.7 1.8 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Peptidase_C37 PF05416.12 KER21209.1 - 0.85 8.1 2.8 1.2 7.5 2.8 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ferritin PF00210.24 KER21213.1 - 2.2e-36 124.9 0.7 2.6e-36 124.7 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KER21213.1 - 0.00099 19.5 0.2 0.0013 19.1 0.2 1.2 1 0 0 1 1 1 1 Rubrerythrin Band_7 PF01145.25 KER21214.1 - 4.8e-27 95.1 0.7 7.8e-27 94.4 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Mad3_BUB1_I PF08311.12 KER21214.1 - 1.1e-11 44.8 0.0 2.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 RVT_1 PF00078.27 KER21214.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Band_7_1 PF13421.6 KER21214.1 - 0.0043 16.8 0.1 0.008 15.9 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Kelch_1 PF01344.25 KER21217.1 - 5.9e-20 70.6 11.0 1.2e-06 28.0 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 KER21217.1 - 9.8e-07 28.5 0.5 2.7 8.1 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KER21217.1 - 4.8e-05 23.5 7.9 0.083 13.2 0.2 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KER21217.1 - 0.00018 21.7 6.6 2.3 8.6 0.1 5.4 6 1 0 6 6 6 2 Kelch motif BTB PF00651.31 KER21217.1 - 0.015 15.5 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain TFIIS_C PF01096.18 KER21219.1 - 3.3e-13 49.2 6.2 1.1e-12 47.6 2.4 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KER21219.1 - 1.3e-09 37.8 4.9 1.5e-08 34.4 0.7 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 KER21219.1 - 0.0021 18.0 1.1 0.0021 18.0 1.1 2.2 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger CpXC PF14353.6 KER21219.1 - 0.0032 17.5 5.7 0.19 11.8 0.4 2.1 1 1 0 2 2 2 2 CpXC protein Gmx_para_CXXCG PF09535.10 KER21219.1 - 0.016 14.5 0.2 0.02 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF3716 PF12511.8 KER21219.1 - 0.022 14.8 4.8 0.75 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.12 KER21219.1 - 0.16 11.5 4.1 0.39 10.3 0.3 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding DUF3268 PF11672.8 KER21219.1 - 0.23 11.8 5.9 0.48 10.8 0.9 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain Cytochrom_NNT PF03264.14 KER21219.1 - 1.1 9.0 6.7 0.17 11.6 1.2 1.9 1 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Rubredoxin_2 PF18073.1 KER21219.1 - 2.8 7.7 10.3 4.4 7.1 0.3 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-C6H2 PF15801.5 KER21220.1 - 0.094 13.0 3.3 0.25 11.7 3.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Anti-TRAP PF15777.5 KER21220.1 - 0.22 11.5 4.6 0.56 10.2 4.6 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein NUFIP1 PF10453.9 KER21221.1 - 9.5e-06 25.4 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) START PF01852.19 KER21222.1 - 1.1e-14 54.3 0.7 5.7e-14 52.0 0.7 2.0 1 1 0 1 1 1 1 START domain PH_8 PF15409.6 KER21222.1 - 1.4e-09 38.1 0.1 2.7e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER21222.1 - 6e-09 36.4 0.0 1.7e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KER21222.1 - 2.2e-05 24.8 0.2 0.0019 18.6 0.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3584 PF12128.8 KER21222.1 - 0.33 8.4 2.9 4.6 4.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) betaPIX_CC PF16523.5 KER21222.1 - 1.6 8.6 4.0 1.1 9.1 1.9 1.8 2 0 0 2 2 2 0 betaPIX coiled coil T2SSM PF04612.12 KER21222.1 - 5.4 7.0 6.7 1.1 9.3 0.4 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF5376 PF17346.2 KER21225.1 - 0.097 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5376) LicD PF04991.13 KER21226.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 LicD family Forkhead PF00250.18 KER21227.1 - 0.00084 19.6 0.0 0.001 19.3 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain SF3A2 PF16835.5 KER21228.1 - 1.8e-38 130.8 0.3 3.2e-38 130.0 0.3 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KER21228.1 - 4.7e-07 30.0 2.0 1e-06 28.9 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KER21228.1 - 0.00047 20.1 0.2 0.00092 19.1 0.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KER21228.1 - 0.75 9.4 3.4 1.5 8.4 3.4 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ras PF00071.22 KER21229.1 - 3.5e-73 244.5 3.1 1.3e-35 122.4 0.1 3.0 1 1 2 3 3 3 3 Ras family Roc PF08477.13 KER21229.1 - 6e-39 133.0 1.5 9.6e-19 67.8 0.1 3.2 2 1 1 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER21229.1 - 2.5e-13 49.9 3.6 3.3e-08 33.2 0.5 3.0 1 1 1 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER21229.1 - 4.2e-06 26.8 0.1 0.88 9.5 0.0 3.2 1 1 0 3 3 3 3 RsgA GTPase GTP_EFTU PF00009.27 KER21229.1 - 7.7e-05 22.3 1.6 0.00035 20.2 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KER21229.1 - 0.00032 20.2 0.7 1.3 8.5 0.1 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KER21229.1 - 0.0027 17.8 0.4 0.5 10.5 0.1 3.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase Omega_Repress PF07764.11 KER21229.1 - 0.0077 16.8 0.2 7.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Omega Transcriptional Repressor Ploopntkinase3 PF18751.1 KER21229.1 - 0.011 15.6 0.2 11 5.9 0.0 3.0 2 1 1 3 3 3 0 P-loop Nucleotide Kinase3 NADH-UOR_E PF16514.5 KER21229.1 - 0.021 15.1 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E TetR_C_16 PF17920.1 KER21229.1 - 0.085 13.1 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TIR_2 PF13676.6 KER21229.1 - 0.18 12.4 0.6 5.7 7.6 0.1 2.5 1 1 1 2 2 2 0 TIR domain Metallophos PF00149.28 KER21229.1 - 0.19 12.2 0.0 31 5.0 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase UBA PF00627.31 KER21232.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Pkinase PF00069.25 KER21234.1 - 1.3e-35 123.1 0.1 1.4e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER21234.1 - 2.7e-14 53.1 0.0 2.1e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER21234.1 - 0.0065 15.8 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like IBN_N PF03810.19 KER21237.1 - 0.00034 20.4 0.1 0.0025 17.7 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain SNF2_N PF00176.23 KER21238.1 - 1.1e-64 218.4 0.0 2.1e-64 217.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KER21238.1 - 1.2e-24 87.1 18.9 2.6e-16 60.2 4.4 3.1 2 1 0 2 2 2 2 DNA-binding domain Helicase_C PF00271.31 KER21238.1 - 7.5e-15 55.2 0.0 2.1e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER21238.1 - 3.5e-07 30.4 0.0 1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KER21238.1 - 0.00027 20.2 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 WD40 PF00400.32 KER21240.1 - 1.8e-14 53.8 2.9 0.00021 22.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KER21240.1 - 0.039 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like DUF2875 PF11394.8 KER21240.1 - 0.064 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) Prominin PF05478.11 KER21241.1 - 8.6e-73 245.6 12.6 2e-58 198.1 3.3 2.5 2 1 0 2 2 2 2 Prominin DUF2207 PF09972.9 KER21241.1 - 3.2e-05 22.9 1.4 0.026 13.3 0.0 3.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 KER21241.1 - 0.029 14.1 2.7 0.16 11.7 0.2 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tmemb_9 PF05434.11 KER21241.1 - 0.031 14.2 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 TMEM9 YtzH PF14165.6 KER21241.1 - 0.035 14.5 1.2 18 5.8 0.0 2.9 2 0 0 2 2 2 0 YtzH-like protein DNA_pol3_tau_5 PF12170.8 KER21241.1 - 0.086 12.9 3.0 0.24 11.4 3.0 1.8 1 1 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Glu-tRNAGln PF02686.15 KER21241.1 - 0.24 11.7 0.9 2.4 8.5 0.2 2.7 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Utp12 PF04003.12 KER21241.1 - 0.92 9.8 5.0 0.29 11.5 0.5 2.5 2 1 0 2 2 2 0 Dip2/Utp12 Family Apolipoprotein PF01442.18 KER21241.1 - 1.1 9.1 14.9 0.15 11.9 3.6 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain PspA_IM30 PF04012.12 KER21241.1 - 1.2 8.7 5.1 5.3 6.6 0.0 2.9 2 1 1 3 3 3 0 PspA/IM30 family CK2S PF15011.6 KER21241.1 - 1.8 8.4 7.7 7.2 6.5 1.8 2.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF2408 PF10303.9 KER21241.1 - 4.2 7.9 8.0 1.4 9.5 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.12 KER21241.1 - 5.9 7.4 8.4 73 3.9 1.1 4.0 4 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein TetR PF13972.6 KER21241.1 - 8 6.2 9.7 4.7 6.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial transcriptional repressor Pkinase PF00069.25 KER21243.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21243.1 - 4.3e-37 127.8 0.0 6.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER21243.1 - 2.3e-08 33.7 0.1 4e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER21243.1 - 7.9e-08 31.9 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KER21243.1 - 2.5e-05 24.0 0.1 0.00039 20.1 0.0 2.4 2 0 0 2 2 2 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KER21243.1 - 4.5e-05 22.6 0.1 4.5e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KER21243.1 - 0.00013 21.9 0.3 0.0026 17.7 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER21243.1 - 0.00018 21.2 0.1 0.00042 20.0 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.11 KER21243.1 - 0.022 14.4 0.5 0.037 13.6 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF4139 PF13598.6 KER21244.1 - 1.1e-20 74.2 0.0 2e-20 73.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KER21245.1 - 0.0025 18.2 4.7 0.37 11.3 1.0 2.6 2 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) TRAP-gamma PF07074.12 KER21245.1 - 0.063 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) CLZ PF16526.5 KER21245.1 - 0.1 13.0 5.9 0.75 10.2 0.5 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KER21245.1 - 0.2 11.7 4.5 6 6.9 0.8 2.4 2 1 0 2 2 2 0 Laminin Domain II SCIMP PF15050.6 KER21245.1 - 0.21 12.0 1.4 0.44 11.0 0.0 2.1 2 1 1 3 3 3 0 SCIMP protein V_ATPase_I PF01496.19 KER21245.1 - 0.46 8.3 11.3 1.2 7.0 11.3 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HR1 PF02185.16 KER21245.1 - 0.53 10.4 13.4 0.27 11.4 1.7 3.2 3 0 0 3 3 3 0 Hr1 repeat DUF4349 PF14257.6 KER21245.1 - 0.7 9.3 7.9 1.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DivIC PF04977.15 KER21245.1 - 0.92 9.3 5.5 1.1 9.1 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 KER21245.1 - 0.93 9.9 0.0 0.93 9.9 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.11 KER21245.1 - 0.97 10.0 5.6 0.87 10.2 0.1 2.7 2 1 0 2 2 2 0 MerR, DNA binding JIP_LZII PF16471.5 KER21245.1 - 1.8 8.8 5.9 8.9 6.6 0.4 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 KER21245.1 - 7.4 6.6 14.7 2.6 8.1 0.7 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 KER21245.1 - 8.2 5.2 5.6 11 4.8 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GRAM PF02893.20 KER21247.1 - 1.2e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KER21247.1 - 0.00082 19.5 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KER21247.1 - 0.26 11.7 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain DUF5535 PF17687.1 KER21247.1 - 5.5 7.2 5.4 3 8.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5535) Tti2 PF10521.9 KER21248.1 - 0.0092 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Tti2 family VWA_3 PF13768.6 KER21249.1 - 4.6e-07 29.9 0.0 6.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KER21249.1 - 0.0054 17.0 0.0 0.009 16.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KER21249.1 - 0.12 13.1 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VIT PF08487.10 KER21250.1 - 1.9e-30 105.3 2.5 5.3e-30 103.9 2.8 1.6 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 KER21250.1 - 3.4e-13 49.3 0.1 6.5e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KER21250.1 - 2.4e-06 28.1 0.0 7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KER21250.1 - 2.5e-06 27.5 0.0 7.3e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KER21250.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Rax2 PF12768.7 KER21250.1 - 0.012 15.0 0.2 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity CobT_C PF11775.8 KER21250.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain EB1 PF03271.17 KER21251.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 EB1-like C-terminal motif tRNA-synt_2c PF01411.19 KER21252.1 - 1.7e-208 693.6 0.0 2.3e-208 693.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KER21252.1 - 1.6e-16 60.1 0.3 4.1e-16 58.8 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KER21252.1 - 2.5e-12 47.4 0.3 2.5e-12 47.4 0.3 1.8 2 0 0 2 2 2 1 DHHA1 domain FUSC PF04632.12 KER21252.1 - 0.36 9.3 1.0 0.57 8.6 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family COPI_C PF06957.11 KER21254.1 - 2e-155 517.5 0.0 1.9e-131 438.6 0.0 2.1 1 1 1 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 KER21254.1 - 3.7e-99 332.8 1.5 5.9e-95 318.9 0.1 2.6 2 1 1 3 3 3 2 Coatomer WD associated region WD40 PF00400.32 KER21254.1 - 6.8e-25 86.9 13.6 5.6e-06 27.0 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER21254.1 - 0.0025 18.1 1.0 2.2 8.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 KER21254.1 - 0.0064 17.1 3.2 2.5 8.8 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER21254.1 - 0.017 15.9 2.3 3.4 8.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER21254.1 - 0.079 13.1 0.7 12 6.3 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Nup160 PF11715.8 KER21254.1 - 0.15 10.7 5.1 3.4 6.2 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KER21254.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain zf-HC5HC2H_2 PF13832.6 KER21255.1 - 2.5e-31 108.1 3.0 2.5e-31 108.1 3.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KER21255.1 - 1.9e-23 82.5 0.2 1.9e-23 82.5 0.2 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KER21255.1 - 1.8e-13 49.8 11.8 1.3e-12 47.1 4.6 3.0 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KER21255.1 - 7.5e-11 41.7 23.3 6.1e-10 38.8 6.9 3.6 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 KER21255.1 - 0.015 15.7 4.5 0.027 14.8 0.0 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like zf-PHD-like PF15446.6 KER21255.1 - 0.017 14.7 1.8 0.017 14.7 1.8 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 KER21255.1 - 8.1 6.9 23.6 0.074 13.4 2.1 3.4 2 1 0 2 2 2 0 Ring finger domain zf-UDP PF14569.6 KER21255.1 - 9.8 6.4 12.1 0.28 11.3 5.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger CDK2AP PF09806.9 KER21256.1 - 7.7e-16 58.9 0.0 1.3e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF4205 PF13898.6 KER21259.1 - 2.8e-48 164.6 0.0 6.7e-43 147.0 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) ParA PF10609.9 KER21260.1 - 3.5e-64 216.6 0.0 4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KER21260.1 - 0.058 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1610 PF07754.11 KER21260.1 - 0.089 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Integrase_H2C2 PF17921.1 KER21263.1 - 0.06 13.5 0.1 0.65 10.1 0.0 2.8 3 0 0 3 3 3 0 Integrase zinc binding domain zf-C2HE PF16278.5 KER21263.1 - 0.45 11.0 4.2 14 6.2 0.1 3.9 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KER21263.1 - 1.3 8.9 11.8 1.6 8.6 0.0 4.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) SPX PF03105.19 KER21264.1 - 2.6e-21 77.0 10.4 1.4e-14 54.8 6.5 2.2 2 0 0 2 2 2 2 SPX domain EXS PF03124.14 KER21264.1 - 4.2e-20 72.3 11.8 6.8e-20 71.7 11.8 1.3 1 0 0 1 1 1 1 EXS family DUF4079 PF13301.6 KER21264.1 - 0.055 13.6 1.7 0.13 12.4 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Babuvirus_MP PF07234.11 KER21264.1 - 1.6 8.9 8.1 0.66 10.2 0.4 3.0 2 1 1 3 3 3 0 Movement and RNA silencing protein Pullulanase_N2 PF17967.1 KER21266.1 - 0.015 16.1 0.4 0.062 14.2 0.1 2.0 1 1 1 2 2 2 0 Pullulanase N2 domain HrpE PF06188.12 KER21266.1 - 0.051 13.5 0.1 0.068 13.1 0.1 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E EXS PF03124.14 KER21267.1 - 2.1e-63 214.7 5.4 3.1e-63 214.1 5.4 1.3 1 0 0 1 1 1 1 EXS family RVT_1 PF00078.27 KER21269.1 - 1.9e-10 40.6 0.0 4.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLAC9 PF15205.6 KER21269.1 - 0.22 11.9 1.2 1 9.8 0.7 2.4 2 0 0 2 2 2 0 Placenta-specific protein 9 SH3_1 PF00018.28 KER21271.1 - 9.3e-07 28.4 0.2 1.7e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_10 PF17902.1 KER21271.1 - 0.00046 20.2 0.1 0.0013 18.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER21271.1 - 0.00078 19.3 0.1 0.0017 18.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PAPS_reduct PF01507.19 KER21272.1 - 3.5e-30 105.3 0.0 5.5e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 KER21272.1 - 1.5e-27 96.0 0.0 3.2e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain RVT_1 PF00078.27 KER21272.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PfkB PF00294.24 KER21274.1 - 7.4e-54 183.1 0.1 9.7e-54 182.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KER21274.1 - 0.037 13.4 0.0 0.087 12.2 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PaO PF08417.12 KER21275.1 - 0.13 12.5 0.1 3.6 7.8 0.0 2.7 2 1 0 2 2 2 0 Pheophorbide a oxygenase Dynein_light PF01221.18 KER21276.1 - 3.9e-31 107.2 1.5 5.8e-31 106.7 1.5 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Fascin PF06268.13 KER21277.1 - 4.6e-30 104.1 0.0 5.8e-15 55.5 0.0 5.6 4 1 1 5 5 5 3 Fascin domain DUF4200 PF13863.6 KER21277.1 - 3.8e-18 66.0 7.7 3.8e-18 66.0 7.7 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4200) FRG1 PF06229.12 KER21277.1 - 1.6e-05 24.7 0.0 0.013 15.2 0.0 3.9 3 0 0 3 3 3 1 FRG1-like domain NPV_P10 PF05531.12 KER21277.1 - 0.16 12.5 0.2 1.3 9.5 0.0 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CoA_binding_2 PF13380.6 KER21277.1 - 0.17 12.4 0.2 4.1 7.9 0.0 2.7 3 0 0 3 3 3 0 CoA binding domain REC114-like PF15165.6 KER21278.1 - 2e-18 67.0 0.0 7.9e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Meiotic recombination protein REC114-like PNK3P PF08645.11 KER21280.1 - 3.1e-52 176.5 0.0 5.1e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KER21280.1 - 3.3e-15 56.5 0.6 1.5e-07 31.7 0.3 2.4 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KER21280.1 - 2.3e-05 23.8 0.1 0.031 13.5 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin Hydrolase_6 PF13344.6 KER21280.1 - 0.019 15.1 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.18 KER21280.1 - 0.033 13.5 0.1 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase YpsA PF06908.11 KER21280.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family HAD PF12710.7 KER21280.1 - 0.23 11.8 0.3 1.3 9.4 0.3 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Got1 PF04178.12 KER21281.1 - 1.6e-32 112.3 10.3 2.4e-32 111.7 10.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2244 PF10003.9 KER21281.1 - 0.045 13.4 0.6 0.085 12.5 0.6 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4064 PF13273.6 KER21281.1 - 0.13 12.5 7.1 1 9.7 7.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) 7tm_1 PF00001.21 KER21282.1 - 1.2e-22 80.6 6.7 1.2e-22 80.6 6.7 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER21282.1 - 1.1e-05 25.3 4.8 1.1e-05 25.3 4.8 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KER21282.1 - 0.13 11.6 6.2 0.034 13.5 2.3 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv LRR19-TM PF15176.6 KER21282.1 - 0.13 12.2 1.6 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3546 PF12066.8 KER21283.1 - 2.9e-38 130.5 1.3 6.3e-38 129.4 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KER21283.1 - 3.7e-32 112.3 4.8 1.4e-31 110.4 4.8 2.0 1 1 0 1 1 1 1 Arsenite-resistance protein 2 GRP PF07172.11 KER21283.1 - 1.6 9.4 11.3 6.6 7.5 11.3 2.0 1 0 0 1 1 1 0 Glycine rich protein family AAA PF00004.29 KER21284.1 - 1.3e-35 122.6 0.0 3e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 KER21284.1 - 5.1e-21 74.5 0.0 1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 KER21284.1 - 1.7e-09 37.3 0.0 5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KER21284.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RRM_1 PF00076.22 KER21285.1 - 1.4e-24 85.7 0.0 1.7e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1198 PF06711.11 KER21285.1 - 0.21 11.7 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Med12-LCEWAV PF12145.8 KER21287.1 - 9.2e-71 239.1 2.2 8.3e-69 232.7 2.2 2.4 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 KER21287.1 - 7.2e-12 45.4 0.1 2e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF2080 PF09853.9 KER21288.1 - 0.041 13.6 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) Memo PF01875.17 KER21289.1 - 4.6e-41 140.8 0.0 6.5e-41 140.3 0.0 1.2 1 1 0 1 1 1 1 Memo-like protein ADK PF00406.22 KER21290.1 - 1.2e-34 119.6 0.0 1.9e-18 67.0 0.0 3.8 3 1 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 KER21290.1 - 4.4e-30 104.9 0.0 1.1e-13 51.8 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_18 PF13238.6 KER21290.1 - 1.1e-14 55.1 0.0 1.1e-06 29.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KER21290.1 - 8e-09 35.8 0.0 0.061 13.5 0.0 3.7 3 2 0 3 3 3 3 AAA domain AAA PF00004.29 KER21290.1 - 1.7e-06 28.5 0.0 0.37 11.2 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KER21290.1 - 1.5e-05 25.3 0.0 2.8 8.2 0.0 4.4 3 2 1 4 4 4 2 AAA domain AAA_22 PF13401.6 KER21290.1 - 5.7e-05 23.4 0.0 0.44 10.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain KTI12 PF08433.10 KER21290.1 - 0.00035 20.1 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KER21290.1 - 0.0012 18.2 0.0 0.15 11.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KER21290.1 - 0.0013 19.1 0.4 5.5 7.4 0.0 4.3 4 1 1 5 5 5 1 RNA helicase AAA_16 PF13191.6 KER21290.1 - 0.0013 19.1 0.0 0.37 11.2 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 KER21290.1 - 0.0069 16.4 0.0 4.3 7.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) CPT PF07931.12 KER21290.1 - 0.035 13.9 0.0 4 7.2 0.0 3.1 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KER21290.1 - 0.053 13.9 0.0 35 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 KER21290.1 - 0.065 12.6 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 KER21290.1 - 0.11 12.4 0.0 16 5.3 0.0 3.1 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KER21290.1 - 0.11 12.2 0.0 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KER21290.1 - 0.13 12.0 0.1 13 5.4 0.0 3.2 4 0 0 4 4 4 0 Thymidylate kinase Hydin_ADK PF17213.3 KER21290.1 - 0.17 12.2 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ASC PF00858.24 KER21292.1 - 2e-18 66.6 0.2 2.4e-18 66.4 0.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UBM PF14377.6 KER21292.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin binding region CD52 PF15116.6 KER21292.1 - 0.19 11.8 1.0 0.42 10.7 1.0 1.6 1 0 0 1 1 1 0 CAMPATH-1 antigen ASC PF00858.24 KER21293.1 - 5.5e-19 68.4 0.1 5.5e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel USP7_C2 PF14533.6 KER21296.1 - 9.6e-55 185.5 0.0 2e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KER21296.1 - 5.3e-45 153.9 0.2 7.7e-45 153.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER21296.1 - 4.4e-19 69.2 0.0 1.3e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KER21296.1 - 4.6e-18 65.4 0.0 2.1e-10 40.3 0.0 3.7 4 0 0 4 4 4 3 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.26 KER21296.1 - 3.4e-12 46.5 0.0 9.3e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 MATH domain Imm5 PF14423.6 KER21299.1 - 0.65 10.2 3.9 1.2 9.3 3.9 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 SET PF00856.28 KER21302.1 - 2.7e-19 70.2 0.1 2.7e-19 70.2 0.1 3.0 2 1 0 2 2 2 1 SET domain WW PF00397.26 KER21302.1 - 5.3e-12 45.6 0.1 1.5e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 WW domain SRI PF08236.11 KER21302.1 - 1.8e-10 40.8 0.0 4.6e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 KER21302.1 - 7e-10 38.8 4.5 7e-10 38.8 4.5 2.0 2 0 0 2 2 2 1 AWS domain DUF4457 PF14652.6 KER21303.1 - 5.2e-126 420.3 0.0 1.4e-81 274.3 0.0 3.8 3 2 0 3 3 3 3 Domain of unknown function (DUF4457) PUB PF09409.10 KER21306.1 - 1e-07 31.8 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 KER21306.1 - 0.00077 19.6 0.0 0.014 15.5 0.0 2.8 2 1 0 2 2 2 1 UBX domain PDZ PF00595.24 KER21307.1 - 3.6e-59 197.1 0.0 3.6e-14 52.9 0.1 6.7 6 0 0 6 6 6 6 PDZ domain PDZ_6 PF17820.1 KER21307.1 - 1.3e-44 149.8 1.3 2.3e-12 46.6 0.1 6.5 6 0 0 6 6 6 6 PDZ domain PDZ_2 PF13180.6 KER21307.1 - 1.3e-21 76.7 0.0 0.00092 19.5 0.0 6.6 6 0 0 6 6 6 5 PDZ domain SelR PF01641.18 KER21309.1 - 1.2e-24 86.7 0.1 1.4e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 SelR domain Ras PF00071.22 KER21312.1 - 4.5e-57 192.2 0.0 5.4e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER21312.1 - 5.2e-23 81.5 0.0 8.2e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER21312.1 - 4.6e-10 39.2 0.0 8e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER21312.1 - 0.0001 21.9 0.1 0.00017 21.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER21312.1 - 0.0021 18.0 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KER21312.1 - 0.05 13.0 0.0 0.064 12.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KER21312.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4498 PF14926.6 KER21313.1 - 8.9e-69 231.5 0.1 1e-68 231.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) ATLF PF07737.11 KER21313.1 - 0.037 13.3 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain PDZ PF00595.24 KER21314.1 - 5e-34 116.5 2.4 1.3e-16 60.7 0.1 4.9 6 0 0 6 6 6 2 PDZ domain PDZ_6 PF17820.1 KER21314.1 - 1.9e-28 98.1 0.4 4.2e-11 42.5 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KER21314.1 - 5.6e-13 49.0 0.0 0.011 16.1 0.0 4.5 5 0 0 5 5 5 3 PDZ domain Tricorn_PDZ PF14685.6 KER21314.1 - 0.00048 20.1 0.3 7.2 6.6 0.0 3.9 4 0 0 4 4 4 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 KER21314.1 - 0.0018 18.6 0.0 0.7 10.3 0.0 2.8 3 0 0 3 3 3 2 PDZ domain DUF2913 PF11140.8 KER21316.1 - 0.03 14.0 3.4 0.047 13.4 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2913) HAD_2 PF13419.6 KER21316.1 - 0.044 13.9 2.8 0.05 13.7 1.9 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF745 PF05335.13 KER21316.1 - 0.72 9.6 9.6 0.045 13.5 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 KER21316.1 - 0.86 9.9 15.3 0.37 11.0 8.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 KER21316.1 - 4.4 8.3 17.6 1.7 9.6 7.8 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_23 PF13476.6 KER21316.1 - 7 7.1 11.0 11 6.5 11.0 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 KER21316.1 - 8.5 5.5 10.9 50 3.0 10.9 1.9 1 1 0 1 1 1 0 TMPIT-like protein KH_1 PF00013.29 KER21318.1 - 2.1e-06 27.4 0.0 0.023 14.5 0.0 2.7 3 0 0 3 3 3 2 KH domain FliT PF05400.13 KER21318.1 - 0.04 14.7 1.1 0.48 11.3 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Agenet PF05641.12 KER21318.1 - 0.087 13.3 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 Agenet domain S6PP_C PF08472.10 KER21319.1 - 0.012 15.5 0.1 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal ArsA_HSP20 PF17886.1 KER21319.1 - 0.018 14.6 0.0 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 HSP20-like domain found in ArsA AIDA PF16168.5 KER21319.1 - 0.025 14.6 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk TEX13 PF15186.6 KER21319.1 - 0.12 12.0 0.5 24 4.6 0.1 2.6 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Resolvase PF00239.21 KER21319.1 - 0.15 12.1 1.5 17 5.5 0.1 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain ATP-grasp_6 PF18419.1 KER21319.1 - 0.18 11.4 0.1 34 4.2 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp-like domain RRM_1 PF00076.22 KER21320.1 - 1.8e-65 216.7 0.4 2.7e-22 78.4 0.2 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KER21320.1 - 7.7e-08 32.2 0.1 0.0061 16.5 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KER21320.1 - 4.2e-05 23.5 0.1 3.3 7.8 0.0 3.5 3 1 1 4 4 4 2 RNA binding motif RRM_7 PF16367.5 KER21320.1 - 0.00025 21.1 0.2 0.91 9.7 0.0 3.8 3 3 0 3 3 3 2 RNA recognition motif SET_assoc PF11767.8 KER21320.1 - 0.00073 19.1 0.2 2.2 8.0 0.0 3.3 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 KER21320.1 - 0.028 14.1 3.3 2.5 7.8 0.3 3.4 3 1 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 KER21320.1 - 0.029 14.4 0.0 6.7 6.9 0.0 3.1 3 1 0 3 3 3 0 Limkain b1 RRM_occluded PF16842.5 KER21320.1 - 0.082 12.8 0.0 23 4.9 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif PABP PF00658.18 KER21321.1 - 3.1e-23 81.7 0.4 4.5e-23 81.2 0.4 1.2 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain DUF1661 PF07877.11 KER21324.1 - 0.12 12.1 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Enolase_C PF00113.22 KER21325.1 - 9.1e-153 507.7 0.1 1.2e-152 507.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KER21325.1 - 3e-58 195.6 0.1 5e-58 194.9 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KER21325.1 - 1.8e-08 34.2 0.0 3.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KER21325.1 - 0.00051 19.3 1.4 0.00091 18.4 0.3 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Ribosomal_S14 PF00253.21 KER21326.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.3 1 1 0 2 2 2 0 Ribosomal protein S14p/S29e MACPF PF01823.19 KER21327.1 - 1.1e-15 58.3 0.0 2.4e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 MAC/Perforin domain WW_like PF17890.1 KER21327.1 - 0.17 12.0 0.3 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain Mito_carr PF00153.27 KER21330.1 - 9.2e-55 182.6 0.3 5.7e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec7_N PF12783.7 KER21332.1 - 1.6e-46 158.1 1.4 1.6e-46 158.1 1.4 4.4 6 1 1 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 KER21332.1 - 5.9e-43 146.7 0.0 1.9e-30 105.9 0.0 2.6 1 1 1 2 2 2 2 Sec7 domain DCB PF16213.5 KER21332.1 - 3.6e-36 124.5 8.4 1.1e-34 119.7 4.7 2.5 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KER21332.1 - 1.4e-28 98.6 1.3 3.1e-27 94.2 0.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF1778 PF08681.11 KER21332.1 - 0.17 11.9 0.9 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) PDEase_I PF00233.19 KER21336.1 - 4.7e-35 121.4 0.1 6e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 KER21337.1 - 9.9e-12 45.1 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NDK PF00334.19 KER21339.1 - 2.9e-102 338.1 0.0 1.2e-36 125.7 0.0 3.2 3 0 0 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 KER21339.1 - 2.5e-05 24.2 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Sigma70_r1_1 PF03979.14 KER21339.1 - 0.013 15.6 2.6 0.09 12.8 0.0 3.4 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 G-gamma PF00631.22 KER21339.1 - 0.14 12.2 1.3 22 5.1 0.0 2.6 2 0 0 2 2 2 0 GGL domain Peptidase_A22B PF04258.13 KER21341.1 - 1.9e-37 129.3 15.5 2.9e-37 128.7 15.5 1.2 1 0 0 1 1 1 1 Signal peptide peptidase RVT_1 PF00078.27 KER21341.1 - 0.0049 16.4 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1516 PF07457.11 KER21341.1 - 0.99 9.6 7.9 1.6 9.0 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DDE_3 PF13358.6 KER21342.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Trp_DMAT PF11991.8 KER21342.1 - 0.097 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase 7TM_GPCR_Srw PF10324.9 KER21346.1 - 5.9e-22 78.4 16.8 2.4e-16 59.9 14.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER21346.1 - 4e-11 42.7 13.7 6.7e-11 42.0 13.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER21346.1 - 0.00087 18.7 12.1 0.0034 16.8 0.0 3.0 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Ldl_recept_a PF00057.18 KER21347.1 - 2.2e-05 24.6 1.2 9.2e-05 22.6 0.2 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.6 KER21347.1 - 0.05 13.5 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 KER21347.1 - 0.31 10.6 2.8 0.5 10.0 2.8 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family RhoGAP PF00620.27 KER21350.1 - 8e-08 32.2 0.2 2.6e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.27 KER21351.1 - 2.1e-05 24.4 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain CUB PF00431.20 KER21352.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.6 2 0 0 2 2 2 1 CUB domain Oxidored_q6 PF01058.22 KER21354.1 - 5e-23 81.4 0.0 5.8e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF4307 PF14155.6 KER21357.1 - 0.14 12.0 2.8 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF4576 PF15144.6 KER21357.1 - 0.21 11.5 1.6 0.52 10.2 0.0 2.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4576) DUF2098 PF09871.9 KER21357.1 - 0.43 10.9 4.6 0.14 12.5 1.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) zf-C2H2_4 PF13894.6 KER21358.1 - 0.015 16.0 7.6 0.32 12.0 1.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KER21358.1 - 0.041 14.3 0.8 0.041 14.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KER21358.1 - 0.42 11.2 8.4 0.054 14.0 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 KER21359.1 - 0.0017 19.1 26.5 0.0019 19.0 0.3 8.7 9 0 0 9 9 9 2 WD domain, G-beta repeat Peptidase_M22 PF00814.25 KER21359.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family ATP-grasp_2 PF08442.10 KER21360.1 - 1.8e-54 184.4 0.0 2.9e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KER21360.1 - 3.2e-22 79.0 1.0 5.9e-22 78.1 1.0 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KER21360.1 - 0.00032 20.2 0.3 0.00095 18.7 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain zf-CCCH PF00642.24 KER21361.1 - 3.7e-16 58.6 12.1 3.7e-08 33.1 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER21361.1 - 4.7e-10 39.0 12.2 8e-07 28.7 1.1 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KER21361.1 - 1.7e-08 34.2 14.1 3.2e-06 27.0 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KER21361.1 - 5.6e-05 23.5 14.7 0.024 15.1 2.0 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KER21361.1 - 0.03 15.0 9.6 5.2 7.8 9.8 2.7 1 1 0 1 1 1 0 Torus domain Tubulin PF00091.25 KER21362.1 - 4.3e-59 200.0 0.0 6.7e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER21362.1 - 3e-42 143.8 0.0 5e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain WD40 PF00400.32 KER21363.1 - 3.6e-59 195.3 18.1 6.8e-07 29.9 0.0 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER21363.1 - 2.1e-17 63.2 1.3 0.023 15.0 0.0 7.2 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER21363.1 - 2.2e-06 27.2 0.0 0.7 9.2 0.0 4.8 3 2 2 5 5 5 2 WD40-like domain Nup160 PF11715.8 KER21363.1 - 1.5e-05 23.8 6.1 0.03 13.0 1.0 4.4 1 1 5 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KER21363.1 - 4.8e-05 22.5 2.0 1.6 7.6 0.1 4.6 3 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein SUZ PF12752.7 KER21365.1 - 2.8e-08 34.4 2.1 5.2e-08 33.5 0.1 2.4 2 0 0 2 2 2 1 SUZ domain Caskin1-CID PF16600.5 KER21365.1 - 3.4 8.3 7.8 0.23 12.1 1.5 2.3 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain PGAP1 PF07819.13 KER21366.1 - 1.8e-33 116.2 0.1 1.5e-32 113.2 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein RhoGEF PF00621.20 KER21370.1 - 2.4e-08 34.4 0.3 4.4e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain Helicase_C PF00271.31 KER21370.1 - 0.13 12.6 0.2 27 5.1 0.1 2.8 1 1 0 2 2 2 0 Helicase conserved C-terminal domain ASC PF00858.24 KER21372.1 - 3.3e-53 181.2 5.5 1.5e-52 179.1 5.5 1.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4369 PF14289.6 KER21372.1 - 0.027 15.0 0.7 0.43 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) Methyltransf_32 PF13679.6 KER21373.1 - 2.8e-17 63.1 0.3 5.9e-16 58.9 0.4 2.5 2 1 0 2 2 2 1 Methyltransferase domain Pkinase PF00069.25 KER21377.1 - 1.3e-31 109.9 0.0 2.2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21377.1 - 2.4e-20 72.9 0.0 3.4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER21377.1 - 0.0022 18.0 0.0 0.094 12.6 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 KER21377.1 - 0.044 13.4 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 SelP_N PF04592.14 KER21377.1 - 0.76 9.1 9.4 1.7 8.0 9.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Gelsolin PF00626.22 KER21378.1 - 5.7e-07 29.3 0.0 0.00092 19.1 0.0 2.5 2 0 0 2 2 2 2 Gelsolin repeat Gelsolin PF00626.22 KER21380.1 - 0.065 13.1 0.4 23 5.0 0.0 3.2 3 0 0 3 3 3 0 Gelsolin repeat UbiA PF01040.18 KER21384.1 - 1.1e-36 126.5 24.1 2.7e-28 99.0 15.5 3.0 2 1 0 2 2 2 2 UbiA prenyltransferase family HOOK PF05622.12 KER21385.1 - 4.5e-85 286.3 14.6 6.2e-85 285.8 14.6 1.1 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 KER21385.1 - 1.7e-05 24.9 29.8 0.0036 17.3 5.3 3.8 4 0 0 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.11 KER21385.1 - 0.00019 20.9 2.3 0.00019 20.9 2.3 2.9 2 1 1 3 3 3 1 Phlebovirus nonstructural protein NS-M DUF3989 PF13150.6 KER21385.1 - 0.019 14.7 0.0 0.077 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) ATG16 PF08614.11 KER21385.1 - 0.028 14.6 39.6 0.19 11.9 3.5 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KER21385.1 - 0.041 14.0 19.9 0.12 12.4 1.2 4.4 2 1 1 4 4 4 0 bZIP transcription factor CH_2 PF06294.11 KER21385.1 - 0.062 13.4 0.2 0.63 10.2 0.0 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein Fez1 PF06818.15 KER21385.1 - 1.4 9.4 27.2 3.3 8.1 12.3 2.6 1 1 2 3 3 3 0 Fez1 MerR_2 PF13591.6 KER21385.1 - 2.1 8.2 7.1 0.21 11.4 0.3 3.0 3 0 0 3 3 2 0 MerR HTH family regulatory protein Atg14 PF10186.9 KER21385.1 - 2.5 7.1 24.2 0.23 10.5 6.2 3.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 KER21385.1 - 2.5 8.3 30.0 0.72 10.1 11.3 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Shugoshin_N PF07558.11 KER21385.1 - 2.7 7.9 8.4 2.3 8.2 0.8 3.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.12 KER21385.1 - 6.9 6.7 33.0 0.74 9.9 2.9 4.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF4250 PF14056.6 KER21385.1 - 7.5 6.6 9.0 9.5 6.3 0.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) ZapB PF06005.12 KER21385.1 - 8 7.0 36.1 1.6 9.3 6.6 4.9 3 1 1 4 4 4 0 Cell division protein ZapB GAS PF13851.6 KER21385.1 - 8 5.8 27.2 16 4.8 0.8 3.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KER21385.1 - 9 7.0 25.2 0.29 11.8 1.0 4.5 3 1 1 4 4 4 0 Initiation control protein YabA MscS_porin PF12795.7 KER21385.1 - 10 5.6 33.6 2.6 7.5 1.6 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Fis1_TPR_C PF14853.6 KER21388.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_4 PF02390.17 KER21388.1 - 0.083 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase SIR2 PF02146.17 KER21393.1 - 1.2e-24 87.2 0.0 1.9e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family GTP_EFTU PF00009.27 KER21395.1 - 2.8e-53 180.4 0.0 5.7e-53 179.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KER21395.1 - 1.7e-22 79.3 0.0 8.5e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KER21395.1 - 1.4e-13 50.6 0.0 3.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KER21395.1 - 6.7e-10 39.2 0.0 1.4e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KER21395.1 - 3e-06 27.1 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KER21395.1 - 0.16 12.5 0.1 0.49 10.9 0.1 1.8 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain NHL PF01436.21 KER21396.1 - 0.024 14.6 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 NHL repeat Lig_chan PF00060.26 KER21397.1 - 6.3e-44 149.4 4.8 3.7e-33 114.5 1.0 2.3 2 0 0 2 2 2 2 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER21397.1 - 6.2e-17 61.8 0.0 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KER21397.1 - 4.4e-15 55.7 0.0 3.7e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ytca PF17090.5 KER21397.1 - 0.027 15.0 3.0 5.9 7.5 0.3 2.8 2 0 0 2 2 2 0 Uncharacterised protein family FAM183 PF14886.6 KER21398.1 - 1.2e-29 103.2 0.7 1.9e-29 102.6 0.7 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related ABC_tran PF00005.27 KER21399.1 - 2e-55 187.0 0.0 6.3e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KER21399.1 - 8e-45 153.4 39.2 2.1e-22 79.7 9.8 4.4 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KER21399.1 - 9e-20 71.7 1.4 7.8e-06 25.9 0.1 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER21399.1 - 0.00013 22.5 1.4 0.041 14.4 0.2 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KER21399.1 - 0.0012 18.3 0.0 6.7 6.1 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KER21399.1 - 0.013 15.2 1.8 0.2 11.4 0.7 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER21399.1 - 0.029 14.3 0.1 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KER21399.1 - 0.03 14.0 0.2 0.93 9.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KER21399.1 - 0.032 13.9 1.6 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KER21399.1 - 0.032 13.5 0.0 5.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KER21399.1 - 0.082 13.1 0.1 6.9 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KER21399.1 - 0.1 12.8 1.8 6.1 7.1 0.8 3.3 2 1 0 2 2 2 0 AAA domain DUF4162 PF13732.6 KER21399.1 - 0.14 12.9 0.0 1.6 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF4079 PF13301.6 KER21399.1 - 1.7 8.8 7.8 11 6.1 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) PIG-P PF08510.12 KER21399.1 - 9.2 6.2 7.3 3.6 7.5 1.1 3.1 2 1 0 2 2 2 0 PIG-P GSHPx PF00255.19 KER21400.1 - 1.3e-07 31.1 0.0 2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Cyclin_N PF00134.23 KER21402.1 - 1.1e-10 41.3 1.5 6.4e-06 25.9 0.5 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KER21402.1 - 0.0055 16.7 0.2 2.1 8.4 0.1 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat LRR_4 PF12799.7 KER21403.1 - 1.1e-14 54.2 22.3 2.7e-07 30.8 3.2 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER21403.1 - 1.5e-08 34.2 10.5 0.00018 21.2 1.1 2.8 1 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KER21403.1 - 3e-06 26.8 6.0 3.1e-06 26.8 4.9 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KER21403.1 - 0.0082 16.1 4.2 1.6 9.0 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 KER21403.1 - 0.039 14.5 5.6 34 5.5 2.2 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat RCC1 PF00415.18 KER21404.1 - 5.2e-52 174.3 18.6 1.8e-08 34.8 0.0 9.5 8 2 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KER21404.1 - 4.9e-19 67.6 34.5 9.4e-05 22.1 0.1 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 KER21405.1 - 2.5e-32 110.4 49.6 2.1e-06 27.9 1.5 7.2 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER21405.1 - 7e-23 81.0 23.2 1.5e-08 34.3 0.3 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 KER21405.1 - 2.3e-18 65.7 82.7 1.9e-06 27.5 3.8 7.0 2 1 8 10 10 10 9 Leucine rich repeat LRR_6 PF13516.6 KER21405.1 - 0.36 11.0 22.5 4.8 7.5 0.0 8.0 10 0 0 10 10 10 0 Leucine Rich repeat DUF2322 PF10084.9 KER21405.1 - 0.42 10.7 4.2 11 6.1 0.0 4.2 2 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_1 PF00560.33 KER21405.1 - 2.3 9.1 41.0 8.2 7.4 0.1 10.1 9 3 0 9 9 9 0 Leucine Rich Repeat LSM PF01423.22 KER21406.1 - 1.7e-11 43.6 0.1 3.5e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 LSM domain Ribosomal_L2_C PF03947.18 KER21406.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Histone PF00125.24 KER21407.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER21407.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER21407.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KER21407.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 KER21407.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Enkurin PF13864.6 KER21409.1 - 9.2e-25 86.9 3.3 1.5e-24 86.2 1.0 2.1 2 0 0 2 2 2 1 Calmodulin-binding ABC_tran PF00005.27 KER21410.1 - 5.9e-52 175.8 0.0 1.7e-28 99.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KER21410.1 - 1.3e-51 175.8 24.5 1.9e-32 113.0 6.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KER21410.1 - 1.1e-10 41.4 0.4 0.0004 19.9 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KER21410.1 - 8.1e-06 25.5 0.4 0.042 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KER21410.1 - 2.1e-05 24.5 3.4 0.66 9.7 0.2 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER21410.1 - 0.00014 22.4 0.2 0.069 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KER21410.1 - 0.00031 20.7 0.2 0.046 13.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KER21410.1 - 0.0012 19.3 0.0 2.1 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KER21410.1 - 0.0015 18.6 5.7 0.84 9.7 0.0 3.9 4 0 0 4 4 3 2 50S ribosome-binding GTPase DUF815 PF05673.13 KER21410.1 - 0.0022 17.2 0.1 1.3 8.1 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF815) DUF87 PF01935.17 KER21410.1 - 0.0086 16.2 1.4 0.18 11.9 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KER21410.1 - 0.028 13.3 0.9 3.1 6.6 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 KER21410.1 - 0.037 13.7 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KER21410.1 - 0.042 12.8 0.0 1.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KER21410.1 - 0.042 14.1 0.1 8.8 6.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KER21410.1 - 0.052 13.5 0.7 17 5.3 0.1 3.1 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 KER21410.1 - 0.091 12.1 0.9 5.2 6.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 KER21410.1 - 0.14 11.4 0.0 7.3 5.7 0.0 2.6 2 0 0 2 2 2 0 KAP family P-loop domain AAA_25 PF13481.6 KER21410.1 - 0.18 11.4 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KER21410.1 - 0.21 11.1 0.6 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4191 PF13829.6 KER21410.1 - 0.66 9.3 6.4 0.028 13.8 0.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4191) Dynamin_N PF00350.23 KER21410.1 - 1.9 8.5 7.9 0.48 10.5 0.5 3.2 3 0 0 3 3 3 0 Dynamin family SH3_7 PF12914.7 KER21411.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain of SH3b2 type KH_1 PF00013.29 KER21412.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-C2H2 PF00096.26 KER21414.1 - 0.0015 18.9 3.1 0.0036 17.7 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type CxxCxxCC PF03692.15 KER21414.1 - 0.018 15.7 3.2 0.027 15.1 3.2 1.4 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain zf-C2H2_4 PF13894.6 KER21414.1 - 0.075 13.9 3.3 0.16 12.9 3.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KER21414.1 - 0.12 12.8 4.4 0.25 11.8 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type EAF PF09816.9 KER21415.1 - 2.2e-20 72.9 0.3 1.4e-19 70.3 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor SPX PF03105.19 KER21415.1 - 4.2 7.2 18.6 5.3 6.8 18.6 1.1 1 0 0 1 1 1 0 SPX domain PTH2 PF01981.16 KER21417.1 - 1.2e-21 77.1 0.0 1.6e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Inositol_P PF00459.25 KER21418.1 - 1.2e-35 123.3 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.32 KER21419.1 - 4.5e-07 30.5 13.8 0.061 14.2 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 KER21419.1 - 9.6e-05 22.3 0.7 0.00021 21.2 0.7 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 PDZ PF00595.24 KER21423.1 - 7.4e-05 23.0 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF717 PF05338.12 KER21423.1 - 0.054 13.6 0.1 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Retinin_C PF04527.12 KER21423.1 - 0.073 13.3 4.6 11 6.4 0.0 3.8 3 1 0 3 3 3 0 Drosophila Retinin like protein DUF1024 PF06260.12 KER21423.1 - 0.13 12.6 0.0 30 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) DUF4729 PF15866.5 KER21424.1 - 0.82 8.9 11.4 12 5.2 6.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) zf-C2H2_aberr PF17017.5 KER21424.1 - 3.6 7.7 7.8 4.6 7.4 0.1 3.1 2 1 1 3 3 3 0 Aberrant zinc-finger Metallophos PF00149.28 KER21425.1 - 8e-41 140.8 0.1 1e-40 140.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER21425.1 - 2.2e-16 60.0 0.9 5.3e-16 58.8 0.5 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 KER21429.1 - 3.1e-24 85.4 0.1 3.4e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KER21429.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.0 1 0 0 1 1 1 0 Ras family SAM_1 PF00536.30 KER21430.1 - 1.1e-22 80.3 1.5 1.2e-09 38.4 0.1 4.2 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER21430.1 - 1.3e-20 73.3 0.1 3.2e-06 27.1 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) Filo_VP35 PF02097.15 KER21430.1 - 3.3 6.7 6.4 0.22 10.6 0.2 2.2 3 0 0 3 3 3 0 Filoviridae VP35 ART PF01129.18 KER21433.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Sld5 PF05916.11 KER21434.1 - 4.1e-08 33.7 2.4 0.0072 16.8 0.2 2.5 2 0 0 2 2 2 2 GINS complex protein Regulator_TrmB PF11495.8 KER21434.1 - 0.0016 17.7 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB ChaB PF06150.12 KER21434.1 - 0.0068 17.0 0.1 8.7 7.0 0.0 2.7 2 0 0 2 2 2 2 ChaB DUF4801 PF16059.5 KER21434.1 - 0.0077 16.2 0.2 7.5 6.6 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4801) E2R135 PF11570.8 KER21434.1 - 0.016 15.5 0.0 9 6.6 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DMAP_binding PF06464.11 KER21434.1 - 0.024 15.4 0.1 54 4.6 0.0 3.8 4 0 0 4 4 4 0 DMAP1-binding Domain CitG PF01874.16 KER21434.1 - 0.1 12.3 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase RelE PF06296.12 KER21434.1 - 0.11 12.6 0.0 25 5.0 0.0 2.4 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system PPDK_N PF01326.19 KER21434.1 - 0.14 11.4 0.0 28 3.8 0.0 2.9 4 0 0 4 4 4 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF1181 PF06680.11 KER21434.1 - 0.16 11.8 0.6 21 4.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1181) PPDFL PF15060.6 KER21434.1 - 0.21 12.1 1.0 30 5.2 0.1 2.4 2 0 0 2 2 2 0 Differentiation and proliferation regulator PyrBI_leader PF08052.11 KER21434.1 - 9.7 6.2 5.9 41 4.2 0.6 2.4 2 0 0 2 2 2 0 PyrBI operon leader peptide Tudor_3 PF18115.1 KER21437.1 - 8.1e-05 22.4 0.0 0.00024 20.9 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 KER21437.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 KER21437.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) TPR_19 PF14559.6 KER21437.1 - 0.15 12.6 0.6 0.3 11.6 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaJ PF00226.31 KER21438.1 - 9.7e-17 60.9 0.7 2e-16 59.9 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain SF3a60_bindingd PF12108.8 KER21438.1 - 0.037 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain TTL PF03133.15 KER21439.1 - 2.5e-103 345.3 0.0 3.2e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER21439.1 - 5.8e-05 22.5 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER21439.1 - 0.0022 17.3 0.0 0.0055 16.0 0.0 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp OST-HTH PF12872.7 KER21440.1 - 2.1e-49 165.2 1.5 3.3e-13 49.3 0.0 7.6 7 0 0 7 7 7 5 OST-HTH/LOTUS domain RRM_1 PF00076.22 KER21440.1 - 0.098 12.5 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_5 PF13909.6 KER21441.1 - 0.00041 20.0 0.6 0.00041 20.0 0.6 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KER21441.1 - 0.0023 18.3 0.7 0.0023 18.3 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KER21441.1 - 0.034 14.8 8.3 2.7 8.7 4.6 2.9 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KER21441.1 - 0.071 14.0 19.5 3.1 8.9 1.4 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER21441.1 - 0.12 12.1 4.4 8 6.3 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KER21441.1 - 0.15 12.4 10.8 2.2 8.7 0.4 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KER21441.1 - 0.17 12.4 0.4 0.17 12.4 0.4 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Galactosyl_T PF01762.21 KER21442.1 - 2e-19 70.2 0.0 2.7e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KER21442.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Pkinase PF00069.25 KER21443.1 - 8e-42 143.4 0.8 1.1e-29 103.6 0.3 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER21443.1 - 2.1e-17 63.3 0.1 3.3e-14 52.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KER21443.1 - 0.012 14.6 0.2 0.019 13.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KER21443.1 - 0.042 12.6 0.1 0.042 12.6 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KER21443.1 - 0.079 12.5 0.1 0.079 12.5 0.1 3.0 2 2 1 3 3 3 0 RIO1 family APH PF01636.23 KER21443.1 - 4.5 7.1 6.4 1.2 9.0 0.0 3.0 4 1 0 5 5 5 0 Phosphotransferase enzyme family TSP_1 PF00090.19 KER21444.1 - 6.3e-06 26.3 9.5 3.7e-05 23.8 9.5 2.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain EGF_2 PF07974.13 KER21444.1 - 0.026 14.9 6.2 0.026 14.9 6.2 5.8 5 2 0 5 5 5 0 EGF-like domain hEGF PF12661.7 KER21444.1 - 0.51 11.1 28.7 6.3 7.6 1.2 6.4 5 0 0 5 5 5 0 Human growth factor-like EGF EGF PF00008.27 KER21444.1 - 2.8 8.4 43.2 0.14 12.4 2.2 5.3 5 0 0 5 5 5 0 EGF-like domain dDENN PF03455.19 KER21446.1 - 2e-05 24.4 2.3 3.6e-05 23.7 0.5 2.0 2 0 0 2 2 2 1 dDENN domain PX PF00787.24 KER21446.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 PX domain Adaptin_N PF01602.20 KER21448.1 - 1.9e-129 432.6 1.8 3e-104 349.5 2.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KER21448.1 - 2.5e-24 85.7 0.3 5.7e-24 84.6 0.3 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KER21448.1 - 4.1e-08 33.4 5.9 1.6e-06 28.2 0.5 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Keratin PF02422.16 KER21448.1 - 0.02 14.6 2.8 3.7 7.3 0.2 2.5 2 0 0 2 2 2 0 Keratin Kinetochor_Ybp2 PF08568.10 KER21448.1 - 0.03 12.8 0.0 0.061 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin RIX1 PF08167.12 KER21448.1 - 0.041 13.6 0.2 0.28 10.9 0.0 2.5 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis RVT_1 PF00078.27 KER21451.1 - 4.9e-06 26.2 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EHD_N PF16880.5 KER21452.1 - 0.093 12.6 0.5 41 4.2 0.0 3.4 3 0 0 3 3 3 0 N-terminal EH-domain containing protein AAA PF00004.29 KER21454.1 - 3.3e-43 147.3 0.0 5.2e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER21454.1 - 7e-11 41.8 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KER21454.1 - 1.6e-07 31.8 0.0 0.00011 22.6 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER21454.1 - 2.2e-06 28.0 0.1 0.00091 19.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KER21454.1 - 3.2e-06 27.4 0.0 2.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KER21454.1 - 8.1e-06 25.9 0.1 0.00014 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KER21454.1 - 9.2e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KER21454.1 - 0.00094 19.4 0.0 0.0021 18.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KER21454.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KER21454.1 - 0.0017 18.9 0.0 0.0047 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KER21454.1 - 0.0021 17.2 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KER21454.1 - 0.0024 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KER21454.1 - 0.0029 17.3 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KER21454.1 - 0.005 17.2 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 KER21454.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KER21454.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KER21454.1 - 0.0092 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KER21454.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 KER21454.1 - 0.032 14.0 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KER21454.1 - 0.037 14.0 0.0 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KER21454.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KER21454.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KER21454.1 - 0.06 12.7 0.1 0.42 9.9 0.0 2.1 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 KER21454.1 - 0.077 12.7 0.0 0.25 11.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KER21454.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KER21454.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KER21454.1 - 0.093 12.3 0.1 0.21 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KER21454.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 KER21454.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KER21454.1 - 0.2 10.8 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) G-patch PF01585.23 KER21455.1 - 1.8e-07 30.9 0.0 4.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 G-patch domain zf-CCCH PF00642.24 KER21455.1 - 0.003 17.4 2.3 0.0064 16.4 2.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER21455.1 - 0.15 12.1 0.7 0.36 11.0 0.7 1.6 1 0 0 1 1 1 0 Zinc finger domain PLAC8 PF04749.17 KER21458.1 - 1.1e-11 45.6 13.7 2.3e-11 44.6 13.7 1.5 1 1 0 1 1 1 1 PLAC8 family TFIID_30kDa PF03540.13 KER21459.1 - 1.6e-17 63.1 0.0 5.2e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Cwf_Cwc_15 PF04889.12 KER21459.1 - 0.26 11.0 7.2 0.48 10.1 7.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KER21459.1 - 0.73 9.1 8.8 1.2 8.4 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 KER21459.1 - 6.1 5.3 6.2 15 4.0 6.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NUDIX PF00293.28 KER21460.1 - 1.4e-14 54.2 0.0 2e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain DUF2570 PF10828.8 KER21460.1 - 0.033 14.0 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) MIase PF02426.16 KER21460.1 - 0.053 13.7 0.6 18 5.6 0.1 2.6 2 0 0 2 2 2 0 Muconolactone delta-isomerase DIL PF01843.19 KER21460.1 - 0.2 12.0 0.9 26 5.2 0.1 2.5 2 0 0 2 2 2 0 DIL domain Amdo_NSP PF12475.8 KER21460.1 - 0.37 10.9 1.5 35 4.6 0.1 2.6 2 0 0 2 2 2 0 Amdovirus non-structural protein SRR1 PF07985.12 KER21462.1 - 0.0024 17.9 0.9 8.8 6.5 0.0 3.3 3 0 0 3 3 3 3 SRR1 DUF2637 PF10935.8 KER21462.1 - 0.05 13.5 0.0 52 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2637) DUF3382 PF11862.8 KER21462.1 - 0.11 12.7 0.0 33 4.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) zf-C2H2 PF00096.26 KER21463.1 - 2.2e-16 59.3 22.8 0.00068 19.9 0.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER21463.1 - 1e-12 47.8 21.6 1.1e-05 25.6 0.9 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER21463.1 - 1.2e-10 41.3 20.5 0.013 16.3 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER21463.1 - 0.017 15.4 7.0 0.64 10.3 7.0 2.5 1 1 0 1 1 1 0 C2H2-type zinc ribbon Raffinose_syn PF05691.12 KER21463.1 - 0.091 10.5 0.0 0.13 10.0 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_11 PF16622.5 KER21463.1 - 0.33 10.8 3.4 7.4 6.4 0.4 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 KER21463.1 - 0.57 10.3 6.1 31 4.6 0.1 3.1 2 1 0 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 KER21463.1 - 0.71 10.1 5.3 0.7 10.2 3.3 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KER21463.1 - 3.4 8.1 7.5 8 6.9 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 KER21463.1 - 6.9 7.5 9.2 11 6.8 2.2 3.0 1 1 1 3 3 3 0 CHORD zf-TRAF PF02176.18 KER21463.1 - 9.9 6.9 11.4 20 6.0 3.5 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger MAPEG PF01124.18 KER21464.1 - 5.1e-17 62.0 1.7 5.9e-17 61.8 1.7 1.0 1 0 0 1 1 1 1 MAPEG family DUF2039 PF10217.9 KER21465.1 - 5.3e-30 103.6 8.8 1e-29 102.7 8.8 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Sec1 PF00995.23 KER21465.1 - 5.4e-27 95.3 0.0 2e-15 57.0 0.0 4.6 3 2 0 3 3 3 3 Sec1 family DUF2797 PF10977.8 KER21465.1 - 0.24 11.3 1.5 0.46 10.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zinc-ribbons_6 PF07191.12 KER21465.1 - 0.83 9.7 6.6 2 8.5 6.6 1.6 1 0 0 1 1 1 0 zinc-ribbons PRTase_2 PF15609.6 KER21466.1 - 0.034 13.6 0.4 0.039 13.4 0.4 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase B1 PF02246.15 KER21466.1 - 0.13 12.3 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein L b1 domain Zn-ribbon_8 PF09723.10 KER21467.1 - 0.096 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain PalH PF08733.10 KER21469.1 - 0.37 9.7 7.0 0.29 10.1 5.6 1.4 1 1 0 1 1 1 0 PalH/RIM21 GWT1 PF06423.12 KER21470.1 - 0.12 12.5 2.5 0.25 11.4 1.8 2.1 2 1 0 2 2 2 0 GWT1 RRM_1 PF00076.22 KER21472.1 - 3.1e-12 46.1 0.0 6.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AurF PF11583.8 KER21472.1 - 0.017 14.4 0.2 0.49 9.6 0.0 2.3 1 1 1 2 2 2 0 P-aminobenzoate N-oxygenase AurF DUF2710 PF10921.8 KER21472.1 - 0.05 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) Nup35_RRM_2 PF14605.6 KER21472.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KER21472.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Sec63 PF02889.16 KER21473.1 - 1.1e-119 398.3 0.0 9.9e-67 224.8 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KER21473.1 - 1e-47 162.2 1.0 6.7e-23 81.4 0.7 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KER21473.1 - 1.1e-24 87.3 0.0 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KER21473.1 - 5.7e-13 49.2 0.0 2.6e-06 27.7 0.0 3.4 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KER21473.1 - 6.6e-07 29.7 0.5 0.088 13.1 0.1 3.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KER21473.1 - 0.0006 20.2 0.6 0.48 10.8 0.3 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KER21473.1 - 0.00072 20.0 0.1 0.38 11.1 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KER21473.1 - 0.0025 17.4 0.4 0.47 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KER21473.1 - 0.01 14.9 0.0 2.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 KER21473.1 - 0.01 15.3 0.1 0.54 9.7 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein Zeta_toxin PF06414.12 KER21473.1 - 0.16 11.2 0.0 18 4.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin MutL_C PF08676.11 KER21475.1 - 5.1e-27 94.5 0.1 1e-26 93.5 0.1 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KER21475.1 - 1.2e-13 50.8 0.0 7.3e-13 48.2 0.0 2.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KER21475.1 - 3.2e-12 46.5 0.1 7.1e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KER21475.1 - 2.8e-07 31.0 0.3 8.4e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMGL-like PF00682.19 KER21477.1 - 1.8e-26 93.3 0.4 8.2e-25 87.9 0.4 2.1 1 1 0 1 1 1 1 HMGL-like FIVAR PF07554.13 KER21479.1 - 0.62 10.9 0.0 0.62 10.9 0.0 3.9 3 1 1 4 4 4 0 FIVAR domain AAA_23 PF13476.6 KER21479.1 - 6.5 7.2 9.2 25 5.3 1.3 2.8 3 0 0 3 3 3 0 AAA domain PIP5K PF01504.18 KER21482.1 - 5.9e-87 291.4 0.0 1.1e-86 290.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sfi1 PF08457.10 KER21486.1 - 4.4e-05 22.2 9.3 5.8e-05 21.8 9.3 1.2 1 0 0 1 1 1 1 Sfi1 spindle body protein TALPID3 PF15324.6 KER21486.1 - 0.074 10.7 0.0 0.097 10.3 0.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target SH2 PF00017.24 KER21488.1 - 8.6e-09 35.4 0.1 2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 KER21488.1 - 2.3e-06 27.9 0.3 6.6e-06 26.4 0.3 1.8 1 0 0 1 1 1 1 SOCS box Tetraspanin PF00335.20 KER21491.1 - 6.5e-39 134.0 22.3 7.4e-39 133.8 22.3 1.0 1 0 0 1 1 1 1 Tetraspanin family ScsC_N PF18312.1 KER21492.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Exo_endo_phos_2 PF14529.6 KER21494.1 - 0.00014 21.7 0.0 0.00096 19.0 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase YTH PF04146.15 KER21495.1 - 1.2e-19 70.8 0.0 3e-09 37.0 0.0 2.9 2 1 0 2 2 2 2 YT521-B-like domain HEAT_2 PF13646.6 KER21496.1 - 3.5e-18 65.8 17.8 0.0028 18.0 0.8 7.8 4 1 6 10 10 10 9 HEAT repeats HEAT PF02985.22 KER21496.1 - 7.5e-17 60.0 26.1 0.0011 19.1 0.2 12.1 12 0 0 12 12 12 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KER21496.1 - 1.5e-05 25.5 0.3 0.23 12.1 0.0 5.3 5 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KER21496.1 - 0.00012 22.2 2.9 0.32 11.0 0.1 4.2 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KER21496.1 - 0.073 12.6 5.9 0.97 8.9 0.0 4.4 4 1 1 5 5 5 0 CLASP N terminal MSP1_C PF07462.11 KER21496.1 - 0.093 11.4 6.5 0.14 10.8 6.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4680 PF15730.5 KER21496.1 - 0.51 10.7 11.3 1.3 9.4 11.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) HEAT_EZ PF13513.6 KER21496.1 - 1.4 9.5 15.6 13 6.4 0.1 6.7 6 2 1 7 7 7 0 HEAT-like repeat Pol_alpha_B_N PF08418.10 KER21496.1 - 1.9 8.4 5.7 3.2 7.7 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribophorin_II PF05817.14 KER21497.1 - 1.9e-106 357.1 2.3 1e-103 348.1 2.3 2.9 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II QVR PF17064.5 KER21498.1 - 1.4e-06 28.5 7.5 1.8e-06 28.1 7.5 1.2 1 0 0 1 1 1 1 Sleepless protein C1_1 PF00130.22 KER21498.1 - 0.014 15.3 0.3 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPAR_LY6 PF00021.21 KER21498.1 - 0.11 13.2 12.2 0.2 12.4 12.2 1.4 1 1 0 1 1 1 0 u-PAR/Ly-6 domain DUF753 PF05444.12 KER21498.1 - 3.7 7.5 11.7 1.1 9.2 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF753) eIF3m_C_helix PF18005.1 KER21499.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Y_phosphatase PF00102.27 KER21500.1 - 7.1e-62 209.0 0.1 1.1e-30 107.0 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KER21500.1 - 1.6e-19 70.2 0.0 2.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KER21500.1 - 7.3e-09 35.9 0.1 1.5e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 KER21500.1 - 0.00012 21.9 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER21500.1 - 0.035 14.1 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CRAL_TRIO_N PF03765.15 KER21500.1 - 0.79 10.0 4.3 18 5.6 0.0 2.9 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KER21501.1 - 2e-13 50.3 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KER21501.1 - 4.7e-06 26.8 0.0 9.9e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Peptidase_M14 PF00246.24 KER21503.1 - 1e-13 51.8 0.1 3.2e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KER21503.1 - 2.1e-08 34.5 0.2 2.1e-08 34.5 0.2 3.2 3 1 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KER21503.1 - 0.0033 16.5 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PSK_trans_fac PF07704.11 KER21503.1 - 4.9 8.0 7.2 5.6 7.8 0.1 2.9 2 0 0 2 2 2 0 Rv0623-like transcription factor TFIID-31kDa PF02291.15 KER21507.1 - 4.5e-05 23.5 0.1 0.00013 22.0 0.1 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 KER21508.1 - 3.5e-62 210.2 0.0 5.6e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21508.1 - 2.3e-45 154.9 0.0 3.4e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER21508.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER21508.1 - 0.00066 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER21508.1 - 0.039 13.9 0.0 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Angiomotin_C PF12240.8 KER21508.1 - 0.15 11.6 0.4 19 4.7 0.0 2.3 2 0 0 2 2 2 0 Angiomotin C terminal DUF5600 PF18150.1 KER21509.1 - 6.1e-42 142.5 0.5 1.2e-41 141.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KER21509.1 - 7.2e-16 58.0 0.0 2.3e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 KER21509.1 - 2.6e-15 56.0 0.7 2.6e-15 56.0 0.7 1.8 2 0 0 2 2 2 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 KER21509.1 - 1.6e-14 54.3 0.0 5.4e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KER21509.1 - 3e-09 37.0 0.0 9.6e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KER21509.1 - 0.0003 20.1 0.0 0.0015 18.0 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KER21509.1 - 0.0007 19.4 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair GTP_EFTU PF00009.27 KER21509.1 - 0.00075 19.1 0.0 0.0043 16.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 KER21509.1 - 0.0051 16.6 0.1 0.077 13.0 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain RsgA_GTPase PF03193.16 KER21509.1 - 0.016 15.2 0.4 1.3 8.9 0.2 2.7 2 1 1 3 3 3 0 RsgA GTPase Roc PF08477.13 KER21509.1 - 0.051 13.8 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KER21509.1 - 0.07 12.7 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 KER21509.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_5 PF13202.6 KER21509.1 - 0.14 11.7 0.3 0.67 9.6 0.3 2.2 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KER21509.1 - 0.15 12.6 1.5 0.59 10.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Thioredoxin PF00085.20 KER21510.1 - 6.3e-14 51.8 0.0 9.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1673 PF07895.11 KER21510.1 - 0.004 16.9 1.9 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1673) TraF PF13728.6 KER21510.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KER21510.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.6 KER21510.1 - 0.18 12.2 0.1 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Fun_ATP-synt_8 PF05933.13 KER21510.1 - 0.33 11.1 5.1 2.3 8.4 0.1 3.3 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) OPA3 PF07047.12 KER21511.1 - 4e-40 136.5 0.1 5.1e-40 136.1 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Sec2p PF06428.11 KER21511.1 - 0.0043 17.0 1.0 0.0062 16.5 1.0 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p FTA4 PF13093.6 KER21511.1 - 0.045 13.6 0.1 0.05 13.5 0.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Rootletin PF15035.6 KER21511.1 - 0.33 11.0 5.4 0.11 12.5 2.9 1.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FGGY_N PF00370.21 KER21512.1 - 3.7e-34 118.4 0.0 7.8e-33 114.0 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KER21512.1 - 1.5e-23 83.6 0.0 3.4e-23 82.4 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RRM_1 PF00076.22 KER21514.1 - 3.9e-16 58.6 0.0 8e-08 32.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER21514.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RNA_pol_L PF01193.24 KER21515.1 - 9.3e-22 76.2 0.0 3.1e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 KER21515.1 - 1.6e-19 70.3 0.0 3.9e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 KER21515.1 - 4.9e-19 67.9 0.0 3.8e-18 65.0 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ephrin_rec_like PF07699.13 KER21516.1 - 2.7e-08 33.4 29.1 8.9e-06 25.4 4.0 4.8 3 2 1 4 4 4 3 Putative ephrin-receptor like NCD3G PF07562.14 KER21516.1 - 0.0035 17.3 30.2 0.021 14.8 1.8 5.0 3 2 1 5 5 5 4 Nine Cysteines Domain of family 3 GPCR RNase_Zc3h12a PF11977.8 KER21517.1 - 2.7e-37 128.0 0.0 3.7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 KER21517.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P DUF5615 PF18480.1 KER21517.1 - 0.12 12.1 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) RNase_Zc3h12a PF11977.8 KER21518.1 - 5.4e-35 120.5 0.0 1e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain RVT_1 PF00078.27 KER21518.1 - 1.9e-13 50.5 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5615 PF18480.1 KER21518.1 - 0.017 14.9 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) PRORP PF16953.5 KER21518.1 - 0.054 13.0 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-only RNase P RRM_1 PF00076.22 KER21519.1 - 4.1e-12 45.7 0.0 8.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER21519.1 - 3.5e-06 26.8 0.1 9e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 KER21519.1 - 3.5e-06 26.9 1.7 3.5e-06 26.9 1.7 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KER21519.1 - 9.8e-06 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KER21519.1 - 4.2e-05 24.2 0.1 8.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 KER21519.1 - 0.0032 17.2 2.2 0.0069 16.2 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KER21519.1 - 0.0054 16.6 2.0 0.0054 16.6 2.0 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KER21519.1 - 0.015 15.7 0.4 0.015 15.7 0.4 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 KER21519.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif zf-CCCH_3 PF15663.5 KER21519.1 - 0.016 15.4 0.2 0.046 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family RRM_7 PF16367.5 KER21519.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif FYVE PF01363.21 KER21519.1 - 0.26 11.5 6.1 0.13 12.5 3.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 KER21519.1 - 0.51 10.4 7.2 1.1 9.3 7.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Myosin_head PF00063.21 KER21521.1 - 9.7e-196 652.0 2.9 1e-130 437.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 KER21521.1 - 1.1e-39 135.3 1.0 1e-22 80.7 0.0 3.9 4 0 0 4 4 4 2 MyTH4 domain FERM_M PF00373.18 KER21521.1 - 1.1e-12 48.4 0.0 1.2e-08 35.3 0.0 3.1 2 0 0 2 2 2 2 FERM central domain IQ PF00612.27 KER21521.1 - 1.3e-12 46.3 20.0 0.0044 16.7 0.6 5.1 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 KER21521.1 - 9.5e-05 22.7 0.1 0.015 15.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain FERM_N PF09379.10 KER21521.1 - 0.00087 19.2 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 FERM N-terminal domain AAA_16 PF13191.6 KER21521.1 - 0.013 15.9 2.1 0.48 10.8 0.0 3.9 4 1 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 KER21521.1 - 0.09 13.3 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RA PF00788.23 KER21521.1 - 0.12 13.0 0.0 0.49 11.1 0.0 2.1 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Rap_GAP PF02145.15 KER21523.1 - 2.8e-05 23.7 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 Rap/ran-GAP Xpo1 PF08389.12 KER21523.1 - 0.062 13.4 0.0 5.8 7.0 0.0 3.2 2 0 0 2 2 2 0 Exportin 1-like protein RRM_1 PF00076.22 KER21525.1 - 0.00012 21.8 0.0 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRXRR PF14239.6 KER21525.1 - 0.0051 16.7 1.7 0.0097 15.8 1.7 1.4 1 0 0 1 1 1 1 RRXRR protein Homeodomain PF00046.29 KER21526.1 - 9.4e-05 22.2 4.8 0.00022 21.0 4.8 1.7 1 1 0 1 1 1 1 Homeodomain Ion_trans_2 PF07885.16 KER21527.1 - 1.8e-36 124.0 15.6 3.4e-19 68.6 4.3 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KER21527.1 - 1.5e-08 34.2 8.8 4.9e-05 22.7 4.6 2.4 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 KER21527.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 2.9 2 2 1 4 4 4 1 Ligand-gated ion channel BCD PF15461.6 KER21527.1 - 0.011 15.3 0.5 0.011 15.3 0.5 2.3 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase FA_desaturase PF00487.24 KER21527.1 - 0.033 14.0 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase YlaC PF10777.9 KER21527.1 - 0.087 12.7 0.2 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF2681 PF10883.8 KER21527.1 - 0.11 12.9 0.2 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) EI24 PF07264.11 KER21527.1 - 0.14 12.4 6.2 1.7 8.9 1.0 2.7 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.9 KER21527.1 - 1.9 7.2 4.9 15 4.2 3.6 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Nop25 PF09805.9 KER21528.1 - 1.3e-13 51.6 7.9 1.3e-13 51.6 7.9 1.6 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATG11 PF10377.9 KER21528.1 - 0.036 14.1 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Autophagy-related protein 11 Macoilin PF09726.9 KER21528.1 - 0.07 11.7 1.8 0.1 11.2 1.8 1.2 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 KER21529.1 - 5.6e-18 64.5 0.0 8.5e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER21529.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 KER21529.1 - 0.00097 19.1 0.4 0.0018 18.2 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KER21529.1 - 0.0013 18.8 2.6 0.0013 18.8 2.6 2.1 3 0 0 3 3 3 1 Zinc knuckle RRM_8 PF11835.8 KER21529.1 - 0.021 15.0 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain NADH_oxidored PF08040.11 KER21529.1 - 0.036 13.8 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 MNLL subunit RRM_occluded PF16842.5 KER21529.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCHC_6 PF15288.6 KER21529.1 - 0.32 10.8 3.1 0.3 11.0 1.3 2.0 1 1 1 2 2 2 0 Zinc knuckle Branch PF02485.21 KER21530.1 - 1.8e-30 106.3 0.1 2.3e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 KER21531.1 - 2e-34 119.2 0.0 2.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme hSac2 PF12456.8 KER21532.1 - 4.8e-17 61.7 0.0 7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase AMP-binding PF00501.28 KER21533.1 - 2e-62 211.2 0.0 2.5e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER21533.1 - 0.0012 19.8 0.0 0.0023 18.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KER21535.1 - 4.4e-59 200.0 0.0 1.2e-58 198.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21535.1 - 3.8e-43 147.6 0.0 5.6e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER21535.1 - 0.0018 17.2 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF1241 PF06840.11 KER21535.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Kinase-like PF14531.6 KER21535.1 - 0.08 12.2 0.1 0.95 8.7 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 KER21537.1 - 3.5e-67 226.5 0.0 5e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21537.1 - 1.4e-45 155.6 0.0 2.1e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KER21537.1 - 2.6e-08 34.1 0.3 0.012 15.9 0.0 3.6 4 0 0 4 4 4 2 P21-Rho-binding domain Kinase-like PF14531.6 KER21537.1 - 2.8e-05 23.6 0.0 5.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER21537.1 - 0.00015 20.7 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER21537.1 - 0.032 14.2 0.1 0.83 9.5 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family ARGLU PF15346.6 KER21541.1 - 2.5e-12 46.9 29.0 2.5e-12 46.9 29.0 2.0 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 DUF445 PF04286.12 KER21541.1 - 0.051 13.4 13.9 0.06 13.2 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HflK_N PF12221.8 KER21541.1 - 2.1 8.4 3.4 15 5.7 0.3 2.5 1 1 1 2 2 2 0 Bacterial membrane protein N terminal Amino_oxidase PF01593.24 KER21541.1 - 2.4 7.3 6.6 2.7 7.2 6.6 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase hDGE_amylase PF14701.6 KER21541.1 - 4.4 6.3 8.8 4.9 6.1 8.8 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain LAMTOR PF15454.6 KER21541.1 - 7.5 7.3 11.0 0.12 13.0 2.4 2.2 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator MFAP1 PF06991.11 KER21543.1 - 0.19 11.5 1.0 0.3 10.9 1.0 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing AMP-binding PF00501.28 KER21544.1 - 1.7e-59 201.5 0.0 2.2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.27 KER21544.1 - 0.00076 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding_C PF13193.6 KER21544.1 - 0.0097 16.9 0.0 0.019 15.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CUB PF00431.20 KER21546.1 - 2.2e-34 118.1 0.0 2.3e-08 34.4 0.0 5.2 5 0 0 5 5 5 5 CUB domain MBA1 PF07961.11 KER21546.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Pkinase PF00069.25 KER21547.1 - 1.1e-62 211.9 0.0 1.7e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21547.1 - 5.4e-37 127.5 0.0 8e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KER21547.1 - 3.9e-18 65.1 18.5 2.5e-13 49.7 9.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KER21547.1 - 3.5e-13 49.7 0.0 6.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 KER21547.1 - 2.3e-07 31.4 1.4 7.4e-07 29.8 1.4 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KER21547.1 - 2.6e-05 23.7 0.0 0.00065 19.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KER21547.1 - 0.0032 16.5 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER21547.1 - 0.0073 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KER21547.1 - 0.027 14.8 8.9 1.8 9.0 5.7 2.8 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 KER21547.1 - 0.046 13.3 12.2 0.44 10.1 0.4 2.8 2 0 0 2 2 2 0 PHD-finger APH PF01636.23 KER21547.1 - 0.06 13.3 0.6 0.21 11.5 0.6 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSNSD PF12062.8 KER21547.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Zf_RING PF16744.5 KER21547.1 - 0.11 12.6 11.7 0.37 10.9 4.9 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 KER21547.1 - 0.75 9.7 14.4 1.5 8.8 1.4 2.5 1 1 1 2 2 2 0 PHD-finger PHD_4 PF16866.5 KER21547.1 - 1.5 9.0 11.5 0.31 11.1 0.9 2.6 1 1 1 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 KER21547.1 - 9.1 6.2 15.9 5.1 7.0 6.8 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Peroxidase_ext PF11895.8 KER21548.1 - 0.079 12.9 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Fungal peroxidase extension region Kinesin PF00225.23 KER21549.1 - 1.9e-22 79.6 0.0 4.2e-11 42.4 0.0 3.2 3 0 0 3 3 3 3 Kinesin motor domain Ion_trans PF00520.31 KER21550.1 - 5.3e-33 114.3 14.0 1.9e-27 96.0 3.9 2.0 1 1 1 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KER21550.1 - 0.013 14.2 6.9 0.052 12.2 6.9 1.9 1 1 0 1 1 1 0 Polycystin cation channel CrgA PF06781.12 KER21550.1 - 0.55 10.3 1.9 0.81 9.8 0.1 2.1 2 0 0 2 2 2 0 Cell division protein CrgA E1-E2_ATPase PF00122.20 KER21550.1 - 4.9 6.6 5.3 1.9 8.0 0.2 2.1 2 0 0 2 2 2 0 E1-E2 ATPase Ion_trans PF00520.31 KER21551.1 - 3.7e-24 85.3 0.1 4.3e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KER21552.1 - 7e-74 248.1 28.9 1.2e-54 185.2 19.9 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KER21552.1 - 1.5e-10 40.4 23.5 0.00085 18.1 19.0 3.3 2 1 0 2 2 2 2 Polycystin cation channel Ca_chan_IQ PF08763.11 KER21553.1 - 9e-18 64.3 0.0 2e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Ion_trans PF00520.31 KER21553.1 - 1.5e-07 30.9 4.4 0.0027 17.0 0.6 2.2 1 1 0 2 2 2 2 Ion transport protein zf-HIT PF04438.16 KER21556.1 - 1.2e-06 28.2 15.3 2.4e-06 27.3 15.3 1.5 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 KER21556.1 - 0.55 8.0 3.4 0.66 7.8 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 OCRE PF17780.1 KER21557.1 - 3.7e-14 52.5 11.8 6.2e-14 51.8 11.8 1.4 1 0 0 1 1 1 1 OCRE domain AhpC-TSA PF00578.21 KER21557.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Phage_TAC_8 PF10666.9 KER21558.1 - 0.024 14.9 3.5 0.04 14.2 2.8 1.6 1 1 1 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 Cnn_1N PF07989.11 KER21558.1 - 0.069 13.3 15.7 0.25 11.5 7.0 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 S6OS1 PF15676.5 KER21558.1 - 0.17 10.4 5.0 0.084 11.3 2.8 1.5 1 1 1 2 2 2 0 Six6 opposite strand transcript 1 family bZIP_Maf PF03131.17 KER21558.1 - 0.41 11.2 8.3 0.79 10.3 1.8 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor SlyX PF04102.12 KER21558.1 - 0.46 11.1 9.4 12 6.6 3.6 3.1 2 1 0 2 2 2 0 SlyX KLRAQ PF10205.9 KER21558.1 - 0.49 10.6 11.6 0.11 12.7 1.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein AAA_11 PF13086.6 KER21558.1 - 0.72 9.6 5.7 0.94 9.2 5.7 1.1 1 0 0 1 1 1 0 AAA domain Cep57_MT_bd PF06657.13 KER21558.1 - 1.5 9.3 13.0 1.4 9.4 3.1 3.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KER21558.1 - 1.8 9.2 13.0 1.7 9.3 2.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 KER21558.1 - 2.2 7.3 8.3 2.6 7.0 8.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 KER21558.1 - 4.8 7.6 12.4 1.8 8.9 1.6 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KER21558.1 - 5.1 7.0 12.3 1.8 8.5 0.6 3.2 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region Viral_P18 PF04521.13 KER21558.1 - 5.2 6.9 6.7 2 8.2 1.8 2.1 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4200 PF13863.6 KER21558.1 - 8.2 6.9 17.8 4.7e+02 1.2 17.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Kinesin PF00225.23 KER21559.1 - 3.7e-91 305.5 0.3 5.3e-91 305.0 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER21559.1 - 2.1e-14 53.7 0.2 5.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Type2_restr_D3 PF16902.5 KER21559.1 - 0.0051 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Type-2 restriction enzyme D3 domain DUF4774 PF15999.5 KER21559.1 - 0.017 14.9 0.7 0.051 13.4 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) ATPase_2 PF01637.18 KER21559.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CREPT PF16566.5 KER21559.1 - 2.4 8.3 7.2 9.6 6.4 2.4 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour RVT_1 PF00078.27 KER21560.1 - 4.4e-23 82.0 0.0 6.9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KER21560.1 - 0.03 14.6 0.1 0.16 12.3 0.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain XRCC4 PF06632.12 KER21561.1 - 5.3e-15 55.1 1.0 5.3e-15 55.1 1.0 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 IFT57 PF10498.9 KER21561.1 - 0.00059 18.9 1.3 0.00074 18.6 1.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Med28 PF11594.8 KER21561.1 - 0.0011 19.0 1.4 0.0015 18.6 1.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 28 RasGAP_C PF03836.15 KER21561.1 - 0.0023 18.1 0.3 0.0033 17.6 0.3 1.4 1 0 0 1 1 1 1 RasGAP C-terminus Peptidase_C12 PF01088.21 KER21561.1 - 0.0044 16.8 0.1 0.0058 16.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1444 PF07285.11 KER21561.1 - 0.0046 16.6 0.3 0.0063 16.1 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1444) TMF_TATA_bd PF12325.8 KER21561.1 - 0.0047 17.1 5.6 0.0099 16.1 5.6 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 KER21561.1 - 0.0058 15.4 1.2 0.0064 15.2 1.2 1.1 1 0 0 1 1 1 1 AAA domain Atg14 PF10186.9 KER21561.1 - 0.0094 15.1 0.8 0.0092 15.1 0.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KER21561.1 - 0.023 14.0 1.5 0.03 13.6 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein HlyD_2 PF12700.7 KER21561.1 - 0.023 13.4 1.0 0.028 13.2 1.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein RmuC PF02646.16 KER21561.1 - 0.023 13.8 2.8 0.033 13.3 2.8 1.1 1 0 0 1 1 1 0 RmuC family DUF3450 PF11932.8 KER21561.1 - 0.025 13.9 3.0 0.034 13.5 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin_2 PF14523.6 KER21561.1 - 0.034 14.5 2.1 0.069 13.5 2.1 1.5 1 0 0 1 1 1 0 Syntaxin-like protein IZUMO PF15005.6 KER21561.1 - 0.039 14.5 0.5 0.057 13.9 0.5 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Dymeclin PF09742.9 KER21561.1 - 0.04 12.3 0.0 0.074 11.5 0.0 1.4 1 1 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein TSC22 PF01166.18 KER21561.1 - 0.062 13.6 2.1 0.062 13.6 2.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family KASH_CCD PF14662.6 KER21561.1 - 0.069 13.0 8.3 0.1 12.4 8.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH LPP PF04728.13 KER21561.1 - 0.11 12.9 1.6 0.23 11.9 1.0 1.9 2 0 0 2 2 1 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 KER21561.1 - 0.16 12.1 4.4 0.23 11.6 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4446 PF14584.6 KER21561.1 - 0.17 11.9 1.9 0.14 12.1 0.5 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4446) YabA PF06156.13 KER21561.1 - 0.18 12.5 4.5 0.34 11.6 4.4 1.5 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KER21561.1 - 0.84 10.1 9.7 0.56 10.7 5.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF2452 PF10504.9 KER21561.1 - 1.4 8.4 4.7 2.2 7.7 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) CLZ PF16526.5 KER21561.1 - 1.7 9.1 6.4 4 7.9 1.8 2.9 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATP-synt_F6 PF05511.11 KER21562.1 - 1.6e-17 63.7 0.0 2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 WD40 PF00400.32 KER21564.1 - 8.1e-18 64.5 24.9 1.2e-05 25.9 0.1 8.2 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER21564.1 - 6e-13 48.9 0.1 8.6e-06 26.0 0.0 5.4 4 3 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KER21564.1 - 0.00062 19.6 0.0 0.7 9.9 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat GIY-YIG PF01541.24 KER21565.1 - 1.3e-11 44.5 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HIT PF04438.16 KER21566.1 - 1.1e-06 28.4 12.3 1.7e-06 27.8 12.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Toxin_38 PF14866.6 KER21566.1 - 0.33 11.3 6.5 0.55 10.6 6.5 1.3 1 0 0 1 1 1 0 Potassium channel toxin zf-MYND PF01753.18 KER21566.1 - 0.59 10.3 7.7 0.98 9.6 7.7 1.3 1 0 0 1 1 1 0 MYND finger UQ_con PF00179.26 KER21567.1 - 4.3e-41 139.8 0.6 6e-41 139.4 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER21567.1 - 0.00017 21.3 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RVT_1 PF00078.27 KER21567.1 - 0.00028 20.5 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RWD PF05773.22 KER21567.1 - 0.0044 17.3 0.6 0.006 16.9 0.6 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KER21567.1 - 0.0072 16.2 0.4 0.015 15.1 0.4 1.5 1 1 0 1 1 1 1 UEV domain MCRS_N PF13325.6 KER21568.1 - 4.5e-27 95.4 0.0 1e-26 94.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein FHA PF00498.26 KER21568.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 KER21570.1 - 5e-14 52.5 2.1 0.13 13.2 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER21570.1 - 0.019 15.2 0.0 29 5.0 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.21 KER21571.1 - 5e-33 113.2 40.4 4.5e-21 75.0 15.2 2.4 3 0 0 3 3 3 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KER21571.1 - 0.9 9.3 4.4 5 6.9 0.3 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain GerA PF03323.13 KER21571.1 - 2.9 6.2 6.3 8.5 4.7 0.2 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Galactosyl_T PF01762.21 KER21572.1 - 2.6e-07 30.7 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase HLH PF00010.26 KER21573.1 - 4.2e-12 45.8 4.6 9.7e-12 44.7 4.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Duo1 PF08651.10 KER21573.1 - 0.11 12.3 1.7 26 4.7 0.0 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 RNase_P_Rpp14 PF01900.19 KER21576.1 - 5.2e-19 68.4 0.0 9.8e-19 67.5 0.0 1.4 1 1 0 1 1 1 1 Rpp14/Pop5 family NatB_MDM20 PF09797.9 KER21577.1 - 1.2e-27 96.9 0.0 3e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KER21577.1 - 1.5e-06 28.5 0.1 0.16 12.9 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KER21577.1 - 0.0015 19.0 0.1 1.5 9.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER21577.1 - 0.019 15.6 0.0 0.046 14.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4919 PF16266.5 KER21577.1 - 0.064 13.2 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) E2_bind PF08825.10 KER21577.1 - 0.09 12.9 0.0 0.42 10.8 0.0 2.2 1 0 0 1 1 1 0 E2 binding domain 5_nucleotid PF05761.14 KER21579.1 - 3.6e-129 431.6 4.1 1.3e-97 327.6 1.5 2.0 2 0 0 2 2 2 2 5' nucleotidase family RVT_1 PF00078.27 KER21581.1 - 8.4e-10 38.5 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-HIT PF04438.16 KER21581.1 - 3.8e-05 23.4 12.0 8.2e-05 22.4 12.0 1.6 1 0 0 1 1 1 1 HIT zinc finger PAC2 PF09754.9 KER21582.1 - 4e-23 82.5 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 PAC2 family PPPI_inhib PF14895.6 KER21583.1 - 1.4e-11 44.2 1.6 2.1e-11 43.6 1.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor MitMem_reg PF13012.6 KER21584.1 - 1.6e-23 83.2 0.2 2.6e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KER21584.1 - 4.4e-16 58.9 0.0 7.7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease adh_short PF00106.25 KER21585.1 - 8.9e-20 71.0 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER21585.1 - 6e-14 52.2 0.0 7.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER21585.1 - 3.6e-06 27.0 0.0 5.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Homeodomain PF00046.29 KER21586.1 - 3.6e-17 62.0 3.5 9.3e-17 60.6 3.5 1.8 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KER21586.1 - 8.8e-16 57.9 31.3 1.6e-11 44.3 12.0 3.5 4 0 0 4 4 4 2 LIM domain Homeobox_KN PF05920.11 KER21586.1 - 8.9e-05 22.3 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain EGF_2 PF07974.13 KER21587.1 - 0.009 16.4 7.5 0.009 16.4 7.5 10.2 9 2 1 10 10 10 4 EGF-like domain Copine PF07002.16 KER21589.1 - 9.3e-44 149.5 0.0 1.5e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KER21589.1 - 0.00056 20.1 0.0 0.0066 16.6 0.0 2.0 1 1 0 2 2 2 1 vWA found in TerF C terminus ESCRT-II PF05871.12 KER21591.1 - 4e-49 166.5 0.1 6.1e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit Arc PF03869.14 KER21591.1 - 0.038 13.8 0.1 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Arc-like DNA binding domain MRG PF05712.13 KER21593.1 - 6e-11 42.0 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 MRG Peptidase_C13 PF01650.18 KER21597.1 - 9.9e-97 323.4 0.3 1.7e-96 322.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER21597.1 - 7.4e-05 22.8 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF2846 PF11008.8 KER21597.1 - 0.057 13.4 0.2 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) Cdc6_C PF09079.11 KER21597.1 - 0.13 12.2 1.0 0.96 9.5 0.5 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Peptidase_C13 PF01650.18 KER21599.1 - 2.9e-63 213.8 4.6 5.7e-40 137.4 0.3 2.2 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C13 PF01650.18 KER21600.1 - 1.2e-93 313.3 0.4 1.7e-93 312.9 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER21600.1 - 2.3e-05 24.5 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER21601.1 - 4e-49 167.4 4.7 8.6e-39 133.6 2.8 2.0 2 0 0 2 2 2 2 Peptidase C13 family Amb_V_allergen PF03913.13 KER21601.1 - 0.17 11.9 0.2 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 Amb V Allergen fn3 PF00041.21 KER21602.1 - 0 1539.6 75.9 7.8e-18 64.6 0.4 34.0 33 0 0 33 33 33 32 Fibronectin type III domain I-set PF07679.16 KER21602.1 - 3.5e-293 946.8 0.0 1.6e-19 69.7 0.0 28.6 27 1 1 28 28 27 26 Immunoglobulin I-set domain Ig_3 PF13927.6 KER21602.1 - 2e-183 595.5 0.1 4.2e-15 56.1 0.0 26.2 25 0 0 25 25 25 23 Immunoglobulin domain Ig_2 PF13895.6 KER21602.1 - 6.5e-95 311.6 0.8 2.1e-12 47.2 0.1 25.2 26 0 0 26 26 26 14 Immunoglobulin domain ig PF00047.25 KER21602.1 - 1e-77 256.4 15.3 1.8e-10 40.8 0.2 18.6 18 0 0 18 18 17 12 Immunoglobulin domain Pkinase PF00069.25 KER21602.1 - 1.1e-68 231.5 0.0 1.9e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KER21602.1 - 8.7e-52 173.9 23.2 0.0022 18.2 0.0 24.9 21 9 2 23 23 20 11 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KER21602.1 - 1.7e-42 143.9 44.7 0.0031 18.0 0.0 27.8 32 0 0 32 32 29 10 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KER21602.1 - 1.5e-36 124.5 0.1 0.11 12.3 0.0 21.8 23 0 0 23 23 23 4 Tissue factor Pkinase_Tyr PF07714.17 KER21602.1 - 1e-34 120.0 0.0 2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Izumo-Ig PF16706.5 KER21602.1 - 1.1e-16 60.6 10.3 0.27 11.3 0.1 14.5 15 0 0 15 15 14 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KER21602.1 - 5.1e-16 58.5 14.2 0.025 14.7 0.0 12.0 13 0 0 13 13 13 2 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.13 KER21602.1 - 4.1e-13 49.1 8.9 23 5.0 0.0 15.1 16 0 0 16 16 14 0 Y_Y_Y domain Ig_6 PF18452.1 KER21602.1 - 3.9e-08 32.7 5.3 1.2 8.8 0.0 8.1 9 0 0 9 9 9 2 Immunoglobulin domain Ig_5 PF16681.5 KER21602.1 - 4.9e-08 33.3 22.1 0.038 14.4 0.2 9.8 10 0 0 10 10 9 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KER21602.1 - 5.8e-08 32.9 21.0 0.14 12.4 0.2 9.3 9 0 0 9 9 9 2 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KER21602.1 - 9.6e-08 32.2 7.9 49 4.2 0.0 12.8 17 0 0 17 17 13 0 Natural killer cell receptor 2B4 CBM_4_9 PF02018.17 KER21602.1 - 4.5e-06 27.0 10.2 1.3 9.3 0.0 11.8 13 0 0 13 13 10 1 Carbohydrate binding domain C1-set PF07654.15 KER21602.1 - 4.3e-05 23.8 15.9 0.13 12.6 0.0 9.3 11 0 0 11 11 9 1 Immunoglobulin C1-set domain bMG6 PF17962.1 KER21602.1 - 5.1e-05 23.4 17.6 55 3.9 0.0 15.8 20 0 0 20 20 14 0 Bacterial macroglobulin domain 6 DUF2369 PF10179.9 KER21602.1 - 0.00012 22.4 0.0 70 3.9 0.0 8.4 11 0 0 11 11 5 0 Uncharacterised conserved protein (DUF2369) RcsC PF09456.10 KER21602.1 - 0.0003 20.7 0.2 32 4.6 0.0 4.5 4 0 0 4 4 4 0 RcsC Alpha-Beta-Loop (ABL) Kdo PF06293.14 KER21602.1 - 0.00094 18.6 0.3 0.0022 17.4 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin PF00028.17 KER21602.1 - 0.0011 19.4 3.8 1.4e+02 3.0 0.0 9.3 10 0 0 10 10 7 0 Cadherin domain zf-C2H2 PF00096.26 KER21602.1 - 0.0017 18.7 8.1 0.028 14.9 4.0 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3146 PF11344.8 KER21602.1 - 0.02 14.5 1.6 29 4.4 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF3146) Adhesin_P1 PF03257.13 KER21602.1 - 0.26 11.9 1.3 24 5.5 0.1 3.7 3 0 0 3 3 3 0 Mycoplasma adhesin P1 CarboxypepD_reg PF13620.6 KER21602.1 - 2.5 8.4 5.5 11 6.3 0.2 5.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain GramPos_pilinBB PF16569.5 KER21604.1 - 0.086 13.7 0.1 0.34 11.7 0.1 1.9 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Homeodomain PF00046.29 KER21611.1 - 2.5e-19 68.9 7.2 4.5e-19 68.0 7.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER21611.1 - 0.025 14.5 0.9 0.06 13.3 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 KER21612.1 - 2.6e-20 72.0 11.1 2.6e-20 72.0 11.1 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KER21612.1 - 1.4 8.9 5.0 0.48 10.4 1.4 2.1 2 0 0 2 2 2 0 Homeobox KN domain Nup88 PF10168.9 KER21614.1 - 8.8e-45 152.7 7.6 8.4e-22 76.8 0.0 3.9 2 1 1 3 3 3 3 Nuclear pore component Spc7 PF08317.11 KER21614.1 - 0.26 10.1 2.4 0.44 9.4 2.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CAP PF00188.26 KER21616.1 - 8.1e-20 71.9 0.0 3.1e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family PTPA PF03095.15 KER21616.1 - 0.068 12.6 0.1 0.1 12.0 0.1 1.3 1 1 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein CAP PF00188.26 KER21617.1 - 2.1e-21 77.0 0.1 1.1e-20 74.8 0.1 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family zf_CCCH_4 PF18345.1 KER21617.1 - 0.14 12.3 5.3 0.35 11.0 1.6 2.7 2 0 0 2 2 2 0 Zinc finger domain CAP PF00188.26 KER21618.1 - 0.00055 20.8 0.8 0.0008 20.2 0.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FERM_M PF00373.18 KER21622.1 - 7.8e-12 45.6 0.1 2.3e-11 44.1 0.1 1.8 1 1 0 1 1 1 1 FERM central domain NOA36 PF06524.12 KER21623.1 - 0.0014 18.0 17.4 0.0015 18.0 17.4 1.2 1 0 0 1 1 1 1 NOA36 protein TLP-20 PF06088.11 KER21623.1 - 0.047 13.6 3.7 0.05 13.5 3.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.11 KER21623.1 - 0.051 13.2 13.8 0.064 12.8 13.8 1.1 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 KER21623.1 - 0.96 8.2 4.7 1.2 8.0 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SGT1 PF07093.11 KER21623.1 - 2.2 6.6 7.2 2.1 6.7 7.2 1.1 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 KER21623.1 - 6.8 4.6 25.9 8.3 4.4 25.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 KER21623.1 - 9.5 6.0 14.3 12 5.8 14.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase_Tyr PF07714.17 KER21624.1 - 3.6e-62 210.0 0.0 5.2e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER21624.1 - 4e-59 200.1 0.0 6.1e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KER21624.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER21624.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KER21624.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Nup88 PF10168.9 KER21624.1 - 0.49 8.2 8.0 0.71 7.6 8.0 1.1 1 0 0 1 1 1 0 Nuclear pore component Strep_pep PF14404.6 KER21626.1 - 0.082 13.2 0.1 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species CKS PF01111.19 KER21626.1 - 0.49 10.7 5.0 0.47 10.8 0.7 2.7 2 1 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Shisa PF13908.6 KER21628.1 - 0.0058 16.9 0.0 0.0071 16.6 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Alpha_E2_glycop PF00943.19 KER21628.1 - 0.011 14.5 1.3 0.013 14.2 1.3 1.0 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein TMEM18 PF14770.6 KER21628.1 - 0.021 14.8 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 18 Cadherin_C_2 PF16492.5 KER21628.1 - 0.024 15.4 0.0 0.031 15.0 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Sarcoglycan_2 PF05510.13 KER21628.1 - 0.052 12.3 0.0 0.059 12.1 0.0 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF4448 PF14610.6 KER21628.1 - 0.15 11.8 0.8 0.18 11.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMIE PF16038.5 KER21628.1 - 0.33 10.8 4.1 0.43 10.4 4.1 1.1 1 0 0 1 1 1 0 TMIE protein Granulin PF00396.18 KER21629.1 - 1.7e-86 284.3 265.8 3.7e-16 59.2 21.4 14.4 11 3 2 13 13 13 10 Granulin DUF1308 PF07000.11 KER21630.1 - 6.1e-26 91.3 0.0 3.3e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KER21630.1 - 0.066 12.5 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5614) 7tm_1 PF00001.21 KER21631.1 - 9.4e-12 44.8 12.5 1.5e-11 44.1 12.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER21631.1 - 2.1e-06 27.3 15.9 0.00086 18.7 4.6 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw FSA_C PF10479.9 KER21632.1 - 1.8e-54 185.1 2.5 7.8e-30 103.6 0.0 5.5 6 0 0 6 6 6 3 Fragile site-associated protein C-terminus Cyclin_N PF00134.23 KER21635.1 - 5e-08 32.7 0.0 7.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KER21635.1 - 1.8e-06 28.4 0.0 2.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin RhoGEF PF00621.20 KER21638.1 - 3.7e-24 86.0 0.0 1.1e-23 84.5 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KER21638.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 PH domain Metallophos PF00149.28 KER21639.1 - 9.8e-36 124.2 0.2 1.5e-35 123.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KER21639.1 - 2.5e-29 101.4 0.3 1.4e-28 99.0 0.1 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 KER21639.1 - 3.4e-15 55.1 6.4 6.1e-06 25.8 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER21639.1 - 4.8e-12 45.0 8.9 0.0011 18.9 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER21639.1 - 6.1e-08 32.2 1.9 3.2e-05 23.5 0.4 2.8 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 KER21639.1 - 2.5e-05 24.4 0.3 0.00014 21.9 0.3 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER21639.1 - 2.7e-05 24.0 3.1 0.29 11.4 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER21639.1 - 0.00018 21.3 0.8 0.03 14.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER21639.1 - 0.00018 20.9 0.9 0.15 11.6 0.1 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 KER21639.1 - 0.00028 21.1 1.8 0.2 12.0 0.2 2.9 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER21639.1 - 0.00047 20.6 0.4 0.13 12.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER21639.1 - 0.00054 20.6 0.8 0.082 13.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER21639.1 - 0.0043 17.3 0.0 0.39 11.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER21639.1 - 0.0048 17.5 0.3 0.93 10.2 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3791 PF12668.7 KER21639.1 - 0.0059 16.6 2.9 7.1 6.8 0.1 4.7 6 0 0 6 6 6 1 Protein of unknown function (DUF3791) MIT PF04212.18 KER21639.1 - 0.014 15.5 5.4 0.49 10.5 0.6 3.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain SRP_TPR_like PF17004.5 KER21639.1 - 0.036 14.1 4.5 0.081 13.0 4.5 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_6 PF13174.6 KER21639.1 - 0.039 14.6 2.4 1.1 10.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KER21639.1 - 0.062 11.7 0.1 0.089 11.1 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal PIF PF05092.12 KER21639.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity DUF2585 PF10755.9 KER21641.1 - 0.068 12.9 0.0 2.5 7.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2585) DUF2573 PF10835.8 KER21644.1 - 0.016 15.6 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Kinesin PF00225.23 KER21645.1 - 3e-16 59.3 0.0 9.2e-15 54.4 0.0 3.0 2 1 0 2 2 2 1 Kinesin motor domain Exo_endo_phos PF03372.23 KER21647.1 - 2.9e-06 27.0 0.0 7.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER21647.1 - 0.017 15.0 0.0 0.043 13.6 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Zmiz1_N PF18028.1 KER21647.1 - 0.03 14.6 0.3 3.3 8.1 0.0 2.8 2 1 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain GTP_EFTU PF00009.27 KER21649.1 - 1.2e-61 207.7 0.0 1.7e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KER21649.1 - 1.3e-35 121.8 0.0 2.5e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KER21649.1 - 2.1e-27 95.0 0.0 4.1e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KER21649.1 - 5.1e-08 33.2 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KER21649.1 - 2.5e-07 30.6 0.1 9.8e-07 28.7 0.0 2.0 3 0 0 3 3 3 1 Class II release factor RF3, C-terminal domain EFG_C PF00679.24 KER21649.1 - 7.3e-06 25.9 0.1 2.6e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus AvrPtoB_bdg PF16847.5 KER21649.1 - 0.002 18.5 0.0 0.042 14.3 0.0 2.5 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.16 KER21649.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KER21649.1 - 0.008 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynein_heavy PF03028.15 KER21649.1 - 0.095 12.8 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain F5_F8_type_C PF00754.25 KER21654.1 - 3.2e-12 46.7 0.0 3.3e-11 43.4 0.0 2.5 2 0 0 2 2 2 1 F5/8 type C domain Nop14 PF04147.12 KER21655.1 - 0.00013 20.4 25.6 0.00015 20.2 25.6 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KER21655.1 - 0.00055 19.5 25.5 0.00061 19.3 25.5 1.1 1 0 0 1 1 1 1 SDA1 SpoIIIAH PF12685.7 KER21655.1 - 0.0022 17.9 2.3 0.0028 17.5 2.3 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein CDC45 PF02724.14 KER21655.1 - 0.0034 15.8 17.9 0.0043 15.4 17.9 1.2 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KER21655.1 - 0.12 11.7 24.3 0.16 11.3 24.3 1.2 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 KER21655.1 - 0.19 10.1 22.2 0.23 9.9 22.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 KER21655.1 - 0.71 8.6 6.8 0.76 8.5 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Kinesin PF00225.23 KER21656.1 - 1.1e-68 231.6 0.2 2.1e-68 230.7 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER21656.1 - 6.8e-35 120.2 0.0 2.6e-34 118.3 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Ras PF00071.22 KER21660.1 - 5.6e-54 182.1 0.0 6.4e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER21660.1 - 2e-29 102.2 0.0 2.8e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER21660.1 - 7.3e-10 38.6 0.0 8.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER21660.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER21660.1 - 0.0009 18.8 0.0 0.0023 17.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER21660.1 - 0.029 14.3 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KER21660.1 - 0.038 13.3 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KER21660.1 - 0.042 13.6 0.0 0.062 13.1 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein CBFD_NFYB_HMF PF00808.23 KER21661.1 - 3.6e-07 30.4 0.0 6.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER21661.1 - 0.38 11.1 4.4 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Collagen PF01391.18 KER21662.1 - 1.4e-160 521.1 632.6 4e-09 36.1 25.4 21.3 2 1 12 14 14 14 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER21662.1 - 2.4e-47 161.2 0.1 3.3e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 KER21662.1 - 6.7e-05 23.5 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KER21662.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 KER21662.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily zf-HIT PF04438.16 KER21664.1 - 2.3e-07 30.6 15.6 4.4e-07 29.7 15.6 1.5 1 0 0 1 1 1 1 HIT zinc finger Myb_DNA-binding PF00249.31 KER21665.1 - 0.0012 19.0 0.2 0.19 12.0 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain UPF0160 PF03690.13 KER21666.1 - 4.5e-124 414.2 0.0 5.1e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) UPF0160 PF03690.13 KER21668.1 - 8.1e-113 377.2 0.0 9.4e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Snf7 PF03357.21 KER21669.1 - 2.2e-18 66.5 6.5 4e-18 65.6 6.5 1.4 1 0 0 1 1 1 1 Snf7 ESCRT-II PF05871.12 KER21669.1 - 7.4e-05 23.0 0.1 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 1 ESCRT-II complex subunit Spectrin PF00435.21 KER21669.1 - 0.012 16.0 6.3 0.028 14.9 5.7 1.9 1 1 0 1 1 1 0 Spectrin repeat Lebercilin PF15619.6 KER21669.1 - 0.25 11.0 16.0 0.43 10.2 15.6 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease 7tm_1 PF00001.21 KER21672.1 - 5.2e-77 258.7 2.1 7.5e-77 258.2 2.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER21672.1 - 4.7e-14 52.4 8.4 2.8e-08 33.5 6.8 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER21672.1 - 2.2e-06 27.5 7.7 7.2e-06 25.8 7.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER21672.1 - 0.015 15.0 2.7 0.05 13.3 1.8 2.0 2 0 0 2 2 2 0 Olfactory receptor TAFII28 PF04719.14 KER21673.1 - 0.061 13.4 0.3 0.36 10.9 0.1 2.0 1 1 1 2 2 2 0 hTAFII28-like protein conserved region TRAM_LAG1_CLN8 PF03798.16 KER21674.1 - 0.00014 21.7 10.0 0.00016 21.5 10.0 1.1 1 0 0 1 1 1 1 TLC domain Pox_A9 PF04835.12 KER21674.1 - 4.1 7.6 9.7 0.85 9.8 4.5 2.4 1 1 1 2 2 2 0 A9 protein conserved region Ribosomal_L35p PF01632.19 KER21675.1 - 8.3e-07 29.4 0.1 1.9e-06 28.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L35 Lipoxygenase PF00305.19 KER21676.1 - 4.3e-34 118.0 0.1 7.3e-33 113.9 0.1 2.1 2 0 0 2 2 2 1 Lipoxygenase PLAT PF01477.23 KER21676.1 - 3.4e-10 40.5 0.1 6.5e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain DUF1414 PF07208.11 KER21676.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Pro_isomerase PF00160.21 KER21677.1 - 1.4e-39 135.9 0.0 1.7e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD V-SNARE_C PF12352.8 KER21678.1 - 4.3e-07 30.1 1.1 7.2e-07 29.4 1.1 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus T2SSF PF00482.23 KER21678.1 - 0.053 13.5 0.6 0.11 12.4 0.6 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF3328 PF11807.8 KER21678.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RVT_1 PF00078.27 KER21680.1 - 0.00031 20.3 0.0 0.00031 20.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4247 PF14042.6 KER21680.1 - 0.21 12.3 0.0 0.25 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Ig_3 PF13927.6 KER21681.1 - 4.9e-53 177.7 3.3 5e-12 46.3 0.0 7.6 7 2 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KER21681.1 - 1.5e-46 156.4 0.0 4.8e-11 42.6 0.0 7.7 7 1 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER21681.1 - 2.7e-37 126.9 0.2 1.9e-06 28.1 0.0 7.7 7 1 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 KER21681.1 - 5.3e-34 116.3 0.0 2.5e-07 30.8 0.0 7.0 6 1 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.21 KER21681.1 - 5.1e-31 106.9 0.4 1.2e-07 32.0 0.1 4.9 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.17 KER21681.1 - 7.7e-19 67.9 0.4 0.012 15.8 0.0 8.4 6 4 1 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KER21681.1 - 2.7e-07 30.0 0.0 0.61 9.7 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KER21681.1 - 1.3e-05 25.6 0.2 0.22 12.1 0.1 4.2 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KER21681.1 - 0.0062 16.6 0.0 1.2 9.2 0.0 4.0 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain UL45 PF05473.12 KER21681.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Ig_C17orf99 PF17736.1 KER21681.1 - 0.067 13.2 3.4 4.4 7.4 0.0 4.8 6 1 0 6 6 6 0 C17orf99 Ig domain MBT PF02820.18 KER21682.1 - 1.3e-71 236.8 0.0 1.7e-23 82.7 0.0 3.3 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.18 KER21683.1 - 5e-12 45.8 5.8 5e-12 45.8 5.8 2.7 3 0 0 3 3 3 2 Zinc finger, C2HC type SAM_1 PF00536.30 KER21685.1 - 5.7e-10 39.5 0.0 9.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER21685.1 - 3.6e-06 27.0 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) AT_hook PF02178.19 KER21685.1 - 0.0048 16.6 2.5 0.013 15.3 2.5 1.8 1 0 0 1 1 1 1 AT hook motif SAM_3 PF18016.1 KER21685.1 - 0.2 11.5 0.1 0.4 10.5 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CAP PF00188.26 KER21687.1 - 1e-10 42.5 5.0 5.5e-10 40.2 5.0 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ExoD PF06055.12 KER21688.1 - 0.047 13.1 0.1 0.089 12.2 0.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Ribosomal_L13 PF00572.18 KER21689.1 - 6.6e-11 42.5 0.0 3.9e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 MFS_1 PF07690.16 KER21690.1 - 1.1e-16 60.7 37.7 1.1e-16 60.7 37.7 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Mucin-like PF16058.5 KER21691.1 - 0.51 10.4 8.1 2.5 8.2 8.2 2.1 1 1 0 1 1 1 0 Mucin-like MIB_HERC2 PF06701.13 KER21692.1 - 1.7e-35 121.1 7.8 1.4e-17 63.7 0.1 3.1 2 0 0 2 2 2 2 Mib_herc2 ZZ PF00569.17 KER21692.1 - 3.4e-09 36.4 6.1 7.7e-09 35.2 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Ank_2 PF12796.7 KER21693.1 - 1.6e-24 86.3 2.0 2e-11 44.3 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER21693.1 - 2.1e-24 85.3 9.6 1.6e-09 37.9 0.3 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER21693.1 - 4.2e-23 81.4 4.4 8.7e-11 42.1 0.4 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KER21693.1 - 3e-20 71.7 12.2 1.4e-06 28.4 0.8 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KER21693.1 - 1.8e-14 52.4 4.9 0.034 14.7 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 KER21694.1 - 2.5e-21 75.3 46.3 1e-10 41.3 7.8 4.5 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 KER21694.1 - 3.5e-11 43.0 8.8 7.2e-06 26.2 1.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KER21694.1 - 1.6e-09 38.2 0.1 9.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER21694.1 - 9e-09 35.4 0.1 0.0015 18.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21694.1 - 3.2e-08 33.2 1.9 0.0095 16.4 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 KER21694.1 - 6e-07 29.2 51.0 3.1e-05 23.7 9.2 5.4 5 1 1 6 6 6 3 Prokaryotic RING finger family 4 Ank_4 PF13637.6 KER21694.1 - 1.4e-06 28.7 0.4 6.6e-05 23.4 0.6 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-C3HC4_2 PF13923.6 KER21694.1 - 5e-05 23.1 9.3 5e-05 23.1 9.3 4.8 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER21694.1 - 0.0038 17.2 45.9 0.089 12.8 4.6 5.4 4 1 1 5 5 5 3 zinc-RING finger domain zf-RING_2 PF13639.6 KER21694.1 - 0.016 15.5 10.1 0.016 15.5 10.1 4.8 3 1 1 4 4 4 0 Ring finger domain Ig_3 PF13927.6 KER21695.1 - 1.9e-42 143.8 5.2 8.6e-10 39.1 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KER21695.1 - 3.8e-36 123.0 0.1 3.5e-08 33.4 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER21695.1 - 9.5e-25 86.8 6.7 4.4e-05 23.7 0.0 5.7 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KER21695.1 - 2e-20 72.7 10.8 6.7e-05 23.0 0.0 5.9 5 2 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 KER21695.1 - 6.7e-16 58.4 0.1 5.6e-09 36.2 0.1 3.1 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.17 KER21695.1 - 2.1e-12 47.2 11.6 0.00015 21.9 0.1 6.4 5 3 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER21695.1 - 7.4e-07 29.2 0.9 0.095 12.8 0.0 3.8 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KER21695.1 - 1.2e-06 28.8 5.5 0.21 12.0 0.0 5.0 5 0 0 5 5 5 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 KER21695.1 - 0.00025 20.5 0.0 0.28 10.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KER21695.1 - 0.036 14.3 1.5 9.7 6.5 0.0 3.5 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Glyco_hydro_36C PF16874.5 KER21695.1 - 0.13 12.8 0.0 16 6.1 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain PDZ PF00595.24 KER21697.1 - 1.1e-20 73.8 0.8 1.8e-20 73.1 0.8 1.3 1 0 0 1 1 1 1 PDZ domain PH_17 PF18012.1 KER21697.1 - 8.6e-18 63.8 0.0 1.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH PF00169.29 KER21697.1 - 2.7e-09 37.5 0.0 0.00098 19.6 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ_6 PF17820.1 KER21697.1 - 4.1e-07 29.8 0.1 8.9e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER21697.1 - 1.5e-05 25.2 0.1 2.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PilM PF07419.12 KER21697.1 - 0.11 12.6 0.0 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 PilM EFG_C PF00679.24 KER21698.1 - 0.053 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus Gal_Lectin PF02140.18 KER21699.1 - 2.9e-05 24.4 1.4 2.9e-05 24.4 1.4 4.0 5 0 0 5 5 5 1 Galactose binding lectin domain Pkinase_Tyr PF07714.17 KER21700.1 - 2.2e-69 233.6 0.0 3.2e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER21700.1 - 1.6e-20 73.6 0.0 1.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Fz PF01392.22 KER21700.1 - 0.0027 18.3 0.2 0.015 15.9 0.2 2.3 1 0 0 1 1 1 1 Fz domain Kringle PF00051.18 KER21700.1 - 0.0064 16.8 0.1 0.61 10.4 0.1 3.0 1 1 0 1 1 1 1 Kringle domain MazG_C PF18722.1 KER21700.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 MazG C-terminal domain DUF3696 PF12476.8 KER21700.1 - 0.11 13.0 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) DZR PF12773.7 KER21700.1 - 2.3 8.3 6.8 2.1 8.5 4.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon DDE_Tnp_IS1595 PF12762.7 KER21701.1 - 9.2e-09 35.5 0.0 4e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 ISXO2-like transposase domain F-box PF00646.33 KER21702.1 - 0.00026 20.8 1.6 0.00089 19.1 0.8 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KER21702.1 - 0.0026 17.6 0.6 0.0026 17.6 0.6 2.8 4 0 0 4 4 4 1 F-box-like F-box_4 PF15966.5 KER21702.1 - 0.0087 15.9 0.2 0.026 14.4 0.2 1.8 1 0 0 1 1 1 1 F-box PRANC PF09372.10 KER21702.1 - 0.046 14.0 0.1 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 PRANC domain RVT_1 PF00078.27 KER21705.1 - 2.7e-10 40.1 0.0 6.1e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KER21705.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4722 PF15849.5 KER21705.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) Forkhead PF00250.18 KER21706.1 - 9e-36 122.0 0.0 2.2e-35 120.8 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain SOCS_box PF07525.16 KER21707.1 - 6.7e-06 26.4 5.1 1.4e-05 25.3 5.1 1.5 1 0 0 1 1 1 1 SOCS box SeqA_N PF17206.3 KER21707.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 SeqA protein N-terminal domain DUF3460 PF11943.8 KER21711.1 - 0.0056 16.9 0.3 0.01 16.1 0.2 1.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3460) PID PF00640.23 KER21712.1 - 7.9e-34 116.7 0.0 7.8e-33 113.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 KER21712.1 - 1.2e-24 86.4 0.3 7.8e-12 45.4 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER21712.1 - 2.5e-13 49.7 0.7 1.4e-06 28.0 0.1 2.6 2 0 0 2 2 2 2 PDZ domain NRho PF16733.5 KER21712.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain PDZ_2 PF13180.6 KER21712.1 - 0.068 13.5 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DUF4218 PF13960.6 KER21713.1 - 0.13 11.9 0.7 0.83 9.3 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4218) Mito_carr PF00153.27 KER21714.1 - 9.5e-09 35.1 0.1 2.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial carrier protein KRTDAP PF15200.6 KER21714.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Keratinocyte differentiation-associated IBR PF01485.21 KER21715.1 - 1.5e-19 69.9 34.7 1e-10 41.7 4.2 3.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KER21715.1 - 0.021 15.1 14.7 0.021 15.1 14.7 4.8 4 0 0 4 4 4 0 Ring finger domain PAP1 PF08601.10 KER21715.1 - 0.073 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 PROCT PF08084.11 KER21715.1 - 0.13 12.2 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 PROCT (NUC072) domain ABC_membrane PF00664.23 KER21716.1 - 3.8e-40 138.3 5.0 5.2e-40 137.8 5.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KER21716.1 - 1.1e-30 107.0 0.0 2.2e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER21716.1 - 6.2e-08 32.4 1.2 2.5e-06 27.1 0.5 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KER21716.1 - 2.9e-05 24.5 0.1 7.2e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KER21716.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 KER21716.1 - 0.0062 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KER21716.1 - 0.013 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KER21716.1 - 0.021 14.4 0.0 0.077 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KER21716.1 - 0.029 14.6 0.2 0.21 11.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KER21716.1 - 0.034 13.9 0.2 0.12 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain Dala_Dala_lig_N PF01820.21 KER21716.1 - 0.063 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AAA_15 PF13175.6 KER21716.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KER21716.1 - 0.073 13.3 0.5 1.8 8.9 0.5 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DHHC PF01529.20 KER21718.1 - 1.6e-36 125.3 10.3 1.6e-36 125.3 10.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 KER21718.1 - 0.88 9.7 4.9 1.6 8.9 4.9 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Mito_carr PF00153.27 KER21719.1 - 1.7e-69 229.8 0.0 2.5e-23 81.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PDZ_6 PF17820.1 KER21720.1 - 4.4e-08 32.8 0.0 1.8e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain RhoGEF PF00621.20 KER21720.1 - 3.3e-07 30.7 0.0 0.0082 16.4 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain PDZ_2 PF13180.6 KER21720.1 - 3.4e-05 24.1 0.0 7.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER21720.1 - 0.0018 18.6 0.0 0.0045 17.3 0.0 1.7 1 1 0 1 1 1 1 PDZ domain HEAT PF02985.22 KER21721.1 - 0.057 13.7 1.1 4.8 7.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Adaptin_N PF01602.20 KER21721.1 - 0.073 11.6 0.1 2.2 6.7 0.1 2.2 1 1 0 1 1 1 0 Adaptin N terminal region SelB-wing_1 PF09105.10 KER21721.1 - 0.077 13.0 0.2 0.25 11.3 0.2 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Ribosomal_L18p PF00861.22 KER21722.1 - 1.3e-07 32.0 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast IQ PF00612.27 KER21723.1 - 0.00025 20.5 0.1 0.00068 19.2 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Baculo_PEP_C PF04513.12 KER21723.1 - 0.14 12.2 9.7 1.6 8.8 0.7 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Octopine_DH PF02317.17 KER21723.1 - 4.2 7.4 7.2 1.8 8.7 3.5 2.1 1 1 1 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Spc7 PF08317.11 KER21723.1 - 4.8 6.0 52.8 0.077 11.9 16.9 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein TraF_2 PF13729.6 KER21723.1 - 6.9 6.0 8.8 1.9 7.8 1.5 2.5 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein MA3 PF02847.17 KER21725.1 - 4.1e-41 139.5 0.2 2.1e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 MA3 domain Peptidase_C54 PF03416.19 KER21727.1 - 6e-83 278.4 0.0 8.2e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 PAN_1 PF00024.26 KER21729.1 - 0.00023 21.1 3.6 0.00059 19.7 3.6 1.6 1 0 0 1 1 1 1 PAN domain DUF4957 PF16318.5 KER21729.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) RasGEF PF00617.19 KER21732.1 - 2e-43 148.7 0.4 4.7e-43 147.4 0.4 1.7 1 0 0 1 1 1 1 RasGEF domain BEN PF10523.9 KER21734.1 - 0.0013 18.9 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 BEN domain Cas6 PF09559.10 KER21736.1 - 0.0068 16.4 0.1 0.0078 16.2 0.1 1.0 1 0 0 1 1 1 1 Cas6 Crispr PepSY_TM_like_2 PF16357.5 KER21736.1 - 0.0098 15.9 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Putative PepSY_TM-like Ets PF00178.22 KER21737.1 - 2.5e-32 111.2 1.0 2.5e-32 111.2 1.0 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 KER21737.1 - 1.5e-13 50.5 0.1 3.2e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain GABP-alpha PF11620.8 KER21737.1 - 6.2e-13 48.7 0.1 1.2e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 GA-binding protein alpha chain TIM PF00121.18 KER21739.1 - 9.4e-49 166.0 0.0 1.2e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase TIM PF00121.18 KER21740.1 - 2.3e-60 204.0 1.5 1.2e-18 67.3 0.1 4.0 2 2 2 4 4 4 4 Triosephosphate isomerase TipAS PF07739.13 KER21740.1 - 0.0016 19.0 0.0 0.43 11.1 0.0 2.2 1 1 1 2 2 2 2 TipAS antibiotic-recognition domain DUF3254 PF11630.8 KER21740.1 - 0.0027 17.8 0.4 2.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3254) HAT PF02184.16 KER21740.1 - 0.14 12.1 1.0 23 5.0 0.1 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat RICTOR_M PF14666.6 KER21740.1 - 0.18 11.6 0.0 4.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Caerin_1 PF07440.12 KER21740.1 - 0.32 11.1 1.0 38 4.5 0.1 2.6 2 0 0 2 2 2 0 Caerin 1 protein TIM PF00121.18 KER21742.1 - 1.4e-92 309.4 0.0 1.6e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ERG4_ERG24 PF01222.17 KER21743.1 - 2.4e-29 102.4 1.8 4.1e-29 101.6 1.8 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NVEALA PF14055.6 KER21743.1 - 0.32 11.0 1.8 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 NVEALA protein DUF2207 PF09972.9 KER21743.1 - 0.53 9.0 2.2 5.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SEA PF01390.20 KER21744.1 - 0.045 13.8 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 SEA domain RRM_5 PF13893.6 KER21746.1 - 0.00084 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER21747.1 - 7.8e-39 132.1 0.1 3.6e-28 97.7 0.1 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER21747.1 - 3.2e-17 62.1 0.0 4.5e-07 29.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KER21747.1 - 5.3e-13 49.0 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 KER21747.1 - 2.8e-06 27.1 0.0 0.032 14.1 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KER21747.1 - 0.00076 19.5 0.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Proteasome PF00227.26 KER21747.1 - 0.0036 16.8 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Limkain-b1 PF11608.8 KER21747.1 - 0.009 16.1 0.2 0.16 12.1 0.0 2.7 3 0 0 3 3 3 1 Limkain b1 RL PF17797.1 KER21747.1 - 0.014 15.3 0.0 1.5 8.8 0.0 3.3 4 0 0 4 4 4 0 RL domain DUF4523 PF15023.6 KER21747.1 - 0.068 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Clr2_transil PF16761.5 KER21749.1 - 0.24 12.3 0.5 23 5.9 0.1 2.5 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 Ribosomal_S19e PF01090.19 KER21752.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e Sdh_cyt PF01127.22 KER21753.1 - 1.1e-20 73.8 1.3 1.5e-20 73.5 1.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UPF0565 PF10561.9 KER21756.1 - 6.6e-40 137.2 0.0 3.5e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 Ras PF00071.22 KER21758.1 - 1.4e-63 213.3 0.2 1.9e-63 212.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER21758.1 - 1.1e-33 116.0 0.2 1.8e-33 115.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER21758.1 - 1.9e-15 56.8 0.1 4.5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER21758.1 - 0.00012 21.5 0.2 0.00018 21.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KER21758.1 - 0.00015 21.7 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KER21758.1 - 0.00017 21.2 0.1 0.00034 20.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KER21758.1 - 0.00058 19.3 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KER21758.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KER21758.1 - 0.043 14.2 0.0 0.066 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KER21758.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KER21758.1 - 0.072 13.4 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KER21758.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF150 PF02576.17 KER21761.1 - 0.031 14.7 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 RimP N-terminal domain 7tm_1 PF00001.21 KER21763.1 - 1.5e-17 63.8 17.9 6.2e-17 61.8 17.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER21763.1 - 1.5e-10 40.9 15.4 4.6e-05 22.8 0.5 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Mntp PF02659.15 KER21763.1 - 0.077 12.7 0.8 0.28 10.9 0.0 2.2 3 0 0 3 3 3 0 Putative manganese efflux pump Ctr PF04145.15 KER21763.1 - 0.082 13.5 1.0 0.23 12.1 1.0 1.8 1 1 0 1 1 1 0 Ctr copper transporter family zf-C2H2 PF00096.26 KER21773.1 - 9.2e-05 22.7 13.2 0.01 16.2 0.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER21773.1 - 0.00097 19.8 12.8 0.0082 16.9 1.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KER21773.1 - 0.016 15.9 1.5 0.043 14.5 1.1 1.9 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KER21773.1 - 0.047 13.4 0.3 0.047 13.4 0.3 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type FYVE PF01363.21 KER21773.1 - 2.4 8.4 11.9 0.33 11.1 6.2 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF5641 PF18701.1 KER21774.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KER21775.1 - 0.00056 20.0 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Flp1_like PF16982.5 KER21775.1 - 0.028 13.8 0.5 0.046 13.1 0.5 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain OATP PF03137.20 KER21775.1 - 0.031 12.6 0.2 0.031 12.6 0.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SMC_N PF02463.19 KER21776.1 - 4.6e-27 94.9 20.5 8e-27 94.1 18.4 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KER21776.1 - 3.8e-24 85.2 0.0 1.4e-23 83.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 KER21776.1 - 9.4e-10 38.7 25.6 9.4e-10 38.7 25.6 3.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KER21776.1 - 6.7e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KER21776.1 - 3.2e-08 33.8 0.0 3.2e-08 33.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER21776.1 - 5.5e-08 33.6 86.7 0.2 12.2 56.2 5.5 2 2 0 2 2 1 1 AAA domain Spc7 PF08317.11 KER21776.1 - 0.00012 21.0 13.4 0.00012 21.0 13.4 4.0 2 1 0 3 3 3 1 Spc7 kinetochore protein ER PF01133.17 KER21776.1 - 0.0028 17.6 2.5 2.1 8.4 0.0 3.4 2 1 0 2 2 2 2 Enhancer of rudimentary DUF1664 PF07889.12 KER21776.1 - 0.0099 15.9 38.9 0.038 14.0 6.1 5.4 3 2 2 5 5 5 4 Protein of unknown function (DUF1664) DUF16 PF01519.16 KER21776.1 - 0.011 16.2 5.8 0.011 16.2 5.8 5.0 2 1 2 4 4 2 0 Protein of unknown function DUF16 ABC_tran PF00005.27 KER21776.1 - 0.015 15.8 0.0 0.015 15.8 0.0 4.4 3 1 0 3 3 2 0 ABC transporter FliJ PF02050.16 KER21776.1 - 0.015 15.5 4.3 0.015 15.5 4.3 5.3 1 1 4 5 5 4 0 Flagellar FliJ protein AAA_5 PF07728.14 KER21776.1 - 0.94 9.5 6.1 3 7.8 0.0 3.4 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) GCS2 PF04107.13 KER21776.1 - 4.2 6.6 7.3 1 8.6 1.3 2.5 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) T3SSipB PF16535.5 KER21776.1 - 5.5 7.5 36.2 0.44 11.0 0.6 5.1 2 2 3 5 5 5 0 Type III cell invasion protein SipB ABC2_membrane PF01061.24 KER21778.1 - 2e-34 118.9 26.2 3.2e-34 118.2 26.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KER21778.1 - 7e-22 78.4 0.0 1.3e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KER21778.1 - 0.002 18.0 0.0 0.14 11.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER21778.1 - 0.004 16.6 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KER21778.1 - 0.029 14.3 0.1 0.085 12.8 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KER21778.1 - 0.03 14.8 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KER21778.1 - 0.096 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ECF-ribofla_trS PF07155.12 KER21778.1 - 1 9.4 9.8 0.13 12.2 0.3 2.5 1 1 1 2 2 2 0 ECF-type riboflavin transporter, S component LCAT PF02450.15 KER21780.1 - 2.4e-45 155.4 0.0 7e-35 120.9 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KER21780.1 - 3.9e-05 23.4 0.0 0.00093 18.9 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF676 PF05057.14 KER21780.1 - 0.00013 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KER21780.1 - 0.0002 22.0 0.0 0.00056 20.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KER21780.1 - 0.013 15.2 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.13 KER21780.1 - 0.13 12.1 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.8 KER21780.1 - 0.21 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MULE PF10551.9 KER21781.1 - 8.2e-08 32.6 0.2 1.4e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 MULE transposase domain 5-FTHF_cyc-lig PF01812.20 KER21781.1 - 3.3e-05 23.8 0.0 5.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 5-FTHF_cyc-lig PF01812.20 KER21782.1 - 8.7e-42 143.1 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2400 PF09674.10 KER21782.1 - 0.19 11.7 0.4 0.28 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF2733 PF10813.8 KER21783.1 - 4.4 7.2 6.7 0.38 10.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Metallophos PF00149.28 KER21784.1 - 5.4e-36 125.0 0.0 8.9e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KER21784.1 - 0.00071 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) DUF1647 PF07801.11 KER21784.1 - 0.058 13.2 0.3 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) PDZ PF00595.24 KER21788.1 - 4.9e-15 55.6 4.8 2.7e-09 37.3 0.2 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER21788.1 - 9.1e-14 51.0 0.2 8.7e-06 25.5 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER21788.1 - 5.2e-09 36.3 1.0 5.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 PDZ domain MARVEL PF01284.23 KER21790.1 - 9.9 6.2 14.3 43 4.1 14.3 2.0 1 1 0 1 1 1 0 Membrane-associating domain HPP PF04982.13 KER21791.1 - 0.091 12.9 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 HPP family Myosin_head PF00063.21 KER21792.1 - 4e-285 947.4 1.6 4e-285 947.4 1.6 2.6 3 0 0 3 3 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KER21792.1 - 1.1e-159 533.4 286.4 2.4e-159 532.3 286.4 1.5 1 1 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KER21792.1 - 1e-11 44.4 6.8 3.1e-11 42.9 6.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ATG16 PF08614.11 KER21792.1 - 7.3e-07 29.6 280.1 0.038 14.2 18.4 10.4 1 1 9 10 10 10 7 Autophagy protein 16 (ATG16) Filament PF00038.21 KER21792.1 - 1.1e-06 28.5 245.0 0.00017 21.3 56.0 8.9 1 1 4 7 7 7 4 Intermediate filament protein DUF1664 PF07889.12 KER21792.1 - 1.2e-06 28.6 156.3 0.094 12.8 0.9 13.7 3 3 9 14 14 14 10 Protein of unknown function (DUF1664) Sec2p PF06428.11 KER21792.1 - 0.00023 21.0 25.9 0.00034 20.5 4.8 15.6 4 4 9 14 14 11 3 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.7 KER21792.1 - 0.0012 19.1 26.7 0.0012 19.1 26.7 11.4 2 2 7 10 10 9 5 Tropomyosin like SlyX PF04102.12 KER21792.1 - 0.0012 19.4 8.7 0.0012 19.4 8.7 20.2 6 4 15 22 22 16 5 SlyX BRE1 PF08647.11 KER21792.1 - 0.0015 18.6 4.6 0.0015 18.6 4.6 15.0 1 1 10 13 13 7 4 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 KER21792.1 - 0.0017 18.6 5.7 0.0017 18.6 5.7 16.2 2 1 12 17 17 14 1 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.6 KER21792.1 - 0.0029 17.3 43.5 0.0029 17.3 43.5 11.0 2 1 8 11 11 9 3 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.20 KER21792.1 - 0.003 17.0 44.6 0.003 17.0 44.6 7.5 1 1 5 6 6 4 1 Tropomyosin IQ PF00612.27 KER21792.1 - 0.0065 16.2 4.0 0.037 13.8 0.4 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 KER21792.1 - 0.1 12.8 0.0 0.1 12.8 0.0 6.1 6 2 1 7 7 7 0 AAA domain Prominin PF05478.11 KER21795.1 - 7.6e-14 50.7 23.5 8.9e-13 47.1 22.9 2.2 2 1 1 3 3 3 1 Prominin LMBR1 PF04791.16 KER21795.1 - 3.7e-05 22.8 0.4 0.00041 19.4 0.0 2.1 1 1 1 2 2 2 1 LMBR1-like membrane protein Tweety PF04906.13 KER21795.1 - 7.8e-05 21.5 12.5 0.0069 15.1 1.2 3.1 2 1 1 3 3 3 2 Tweety DUF2207 PF09972.9 KER21795.1 - 0.0002 20.3 6.5 0.0051 15.6 0.0 3.4 3 1 1 4 4 4 1 Predicted membrane protein (DUF2207) FliD_C PF07195.12 KER21795.1 - 0.089 12.2 5.0 0.37 10.2 0.4 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Apolipoprotein PF01442.18 KER21795.1 - 0.17 11.7 0.7 0.39 10.6 0.7 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2884 PF11101.8 KER21795.1 - 0.31 10.5 5.6 2.6 7.5 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) APG17 PF04108.12 KER21795.1 - 0.39 9.8 10.2 0.17 11.0 6.7 1.9 1 1 1 2 2 2 0 Autophagy protein Apg17 SKA2 PF16740.5 KER21795.1 - 0.39 10.5 9.1 0.68 9.7 1.0 3.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 KER21795.1 - 0.41 10.7 17.0 77 3.3 16.9 3.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KER21795.1 - 0.54 10.3 8.1 5.3 7.1 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF1218 PF06749.12 KER21795.1 - 0.71 10.4 15.3 0.36 11.4 1.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Spore_III_AB PF09548.10 KER21795.1 - 0.77 9.9 4.8 1.4 9.0 2.1 2.6 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) BST2 PF16716.5 KER21795.1 - 1.2 9.7 8.9 0.27 11.8 1.3 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HSBP1 PF06825.12 KER21795.1 - 1.5 8.7 6.9 16 5.4 0.7 4.0 4 0 0 4 4 4 0 Heat shock factor binding protein 1 ZYG-11_interact PF05884.12 KER21795.1 - 2.3 7.5 8.2 4.4 6.6 0.2 2.6 1 1 1 2 2 2 0 Interactor of ZYG-11 NB PF04159.13 KER21795.1 - 2.6 8.1 7.7 0.7 10.0 1.5 3.0 3 0 0 3 3 2 0 NB glycoprotein Bax1-I PF01027.20 KER21795.1 - 9.9 5.9 28.4 0.22 11.3 2.5 3.4 3 1 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 Ras PF00071.22 KER21797.1 - 6.7e-26 90.8 0.0 8.1e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KER21797.1 - 4.1e-06 26.3 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KER21797.1 - 2.9e-05 24.3 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TPP_enzyme_M PF00205.22 KER21797.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ER_lumen_recept PF00810.18 KER21798.1 - 1.2e-23 84.6 1.7 1.2e-23 84.6 1.7 2.0 2 1 0 2 2 2 1 ER lumen protein retaining receptor Pkinase PF00069.25 KER21799.1 - 2.2e-48 164.9 0.0 5.2e-35 121.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER21799.1 - 2e-32 112.5 0.0 2.1e-30 105.9 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER21799.1 - 0.0096 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KER21799.1 - 0.038 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KER21799.1 - 0.046 12.5 0.0 0.088 11.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KER21799.1 - 0.098 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Asp PF00026.23 KER21800.1 - 1e-26 94.2 0.0 1.1e-26 94.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER21800.1 - 1.3e-06 28.3 0.0 1.7e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER21801.1 - 3.6e-18 66.1 0.1 4.3e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER21801.1 - 2e-05 24.4 0.1 3.1e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal BolA PF01722.18 KER21801.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 BolA-like protein LAP2alpha PF11560.8 KER21802.1 - 0.013 15.0 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha FAD_binding_6 PF00970.24 KER21802.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Asp PF00026.23 KER21803.1 - 1.3e-24 87.2 0.0 1.5e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER21803.1 - 5.3e-06 26.3 0.1 8e-05 22.5 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal WAPL PF07814.13 KER21805.1 - 4.1e-56 190.3 0.4 3.2e-33 115.0 0.1 3.8 2 2 1 3 3 3 3 Wings apart-like protein regulation of heterochromatin Cwf_Cwc_15 PF04889.12 KER21805.1 - 0.0039 17.0 15.1 0.0039 17.0 15.1 3.8 4 0 0 4 4 4 1 Cwf15/Cwc15 cell cycle control protein Exo_endo_phos_2 PF14529.6 KER21805.1 - 0.0044 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TACI-CRD2 PF09305.10 KER21805.1 - 0.0075 16.3 0.2 6.9 6.8 0.0 2.5 2 0 0 2 2 2 2 TACI, cysteine-rich domain NPR3 PF03666.13 KER21805.1 - 0.41 9.4 13.9 0.0081 15.0 5.3 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 7tm_1 PF00001.21 KER21807.1 - 5.8e-08 32.4 10.7 2.2e-06 27.2 10.7 2.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FHA PF00498.26 KER21808.1 - 7.6e-17 61.4 0.0 5.6e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 FHA domain TSC22 PF01166.18 KER21808.1 - 0.00036 20.8 0.1 0.00036 20.8 0.1 5.2 6 1 1 7 7 7 2 TSC-22/dip/bun family DUF2968 PF11180.8 KER21808.1 - 0.0033 17.1 7.3 0.0033 17.1 7.3 3.6 3 2 0 3 3 3 1 Protein of unknown function (DUF2968) ERM PF00769.19 KER21808.1 - 0.0063 16.4 15.2 0.0063 16.4 15.2 3.4 2 1 1 3 3 3 2 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 KER21808.1 - 0.014 15.7 2.6 0.014 15.7 2.6 3.7 2 1 1 3 3 3 0 Zinc finger-containing protein DUF2785 PF10978.8 KER21808.1 - 0.034 13.9 0.5 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Yop-YscD_cpl PF16697.5 KER21808.1 - 0.051 13.9 0.0 0.26 11.6 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Phage_GP20 PF06810.11 KER21808.1 - 0.078 12.8 14.4 0.44 10.3 0.8 4.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 HALZ PF02183.18 KER21808.1 - 3.1 8.1 16.9 0.42 10.9 0.6 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 KER21808.1 - 9.6 6.5 25.3 0.73 10.1 5.9 3.9 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF3667 PF12412.8 KER21809.1 - 0.23 11.0 0.3 0.23 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) Snf7 PF03357.21 KER21810.1 - 1.1e-11 44.6 11.4 1.1e-11 44.6 11.4 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 KER21810.1 - 4.3e-06 26.8 3.5 6e-06 26.3 3.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF720 PF05302.11 KER21810.1 - 0.02 14.7 0.5 0.04 13.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF2155 PF09923.9 KER21811.1 - 4.1e-05 23.7 0.0 0.93 9.8 0.0 3.3 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2155) DUF3669 PF12417.8 KER21811.1 - 0.15 12.3 0.0 53 4.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger protein Tmemb_161AB PF10268.9 KER21816.1 - 3.5e-76 256.8 8.4 4.3e-76 256.5 8.4 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB MATH PF00917.26 KER21817.1 - 0.02 15.0 0.6 1 9.6 0.1 3.5 3 1 0 3 3 3 0 MATH domain CDT1_C PF16679.5 KER21818.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain CDT1_C PF16679.5 KER21819.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain zf-C2HC PF01530.18 KER21820.1 - 1.1e-07 31.9 2.5 3.3e-07 30.4 2.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2HC type DUF1190 PF06693.11 KER21820.1 - 0.01 16.2 4.0 0.015 15.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) PAS_3 PF08447.12 KER21822.1 - 7.3e-14 51.8 0.7 2.2e-08 34.3 0.1 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KER21822.1 - 2.7e-12 46.8 1.4 2e-09 37.5 0.3 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KER21822.1 - 1.9e-09 37.5 0.1 3.1e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KER21822.1 - 0.0086 16.3 0.0 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain EF-hand_1 PF00036.32 KER21823.1 - 6e-28 94.3 9.7 6.8e-07 28.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER21823.1 - 3.1e-24 82.8 4.9 5.8e-06 25.8 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER21823.1 - 2.8e-23 80.3 8.9 2.1e-06 27.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER21823.1 - 6.8e-21 74.5 7.9 5.9e-10 39.5 1.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KER21823.1 - 1.1e-13 50.8 7.3 1.4e-05 24.8 0.4 4.0 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER21823.1 - 1e-08 35.5 3.8 7.5e-05 23.0 0.3 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER21823.1 - 3.7e-06 27.2 0.2 0.017 15.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KER21823.1 - 0.00036 20.4 5.2 0.2 11.6 0.1 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CesT PF05932.13 KER21823.1 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family DUF2312 PF10073.9 KER21823.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Dockerin_1 PF00404.18 KER21823.1 - 0.031 14.5 0.0 0.66 10.2 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain Toprim_2 PF13155.6 KER21823.1 - 0.037 14.4 0.2 1.1 9.7 0.0 2.6 1 1 2 3 3 3 0 Toprim-like EF-hand_10 PF14788.6 KER21823.1 - 0.07 13.0 3.5 2.2 8.2 0.1 3.3 2 1 0 2 2 2 0 EF hand DUF3463 PF11946.8 KER21823.1 - 0.091 12.6 0.2 2 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) Ion_trans PF00520.31 KER21824.1 - 2.3e-29 102.4 5.6 3.1e-29 101.9 5.6 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER21824.1 - 1.4e-12 47.4 0.2 1.4e-12 47.4 0.2 2.8 4 0 0 4 4 4 1 Ion channel PAS_9 PF13426.7 KER21824.1 - 5.6e-10 39.4 0.0 7.2e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain cNMP_binding PF00027.29 KER21824.1 - 2.7e-09 37.0 0.0 1.4e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PAS PF00989.25 KER21824.1 - 7.4e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KER21824.1 - 0.00028 21.1 0.0 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold HEAT_2 PF13646.6 KER21827.1 - 1.9e-20 73.0 6.0 5.8e-09 36.2 0.3 3.9 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 KER21827.1 - 9.8e-11 41.0 6.4 0.041 14.1 0.0 5.7 7 1 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 KER21827.1 - 1.2e-10 41.0 10.6 0.0074 16.9 0.0 6.9 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KER21827.1 - 0.0008 19.9 9.3 1.8 9.1 0.3 5.5 5 2 1 6 6 6 3 HEAT-like repeat IFRD PF05004.13 KER21827.1 - 0.05 12.7 0.0 0.9 8.6 0.0 2.4 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Scaffolding_pro PF11418.8 KER21827.1 - 0.063 13.8 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein FYVE PF01363.21 KER21828.1 - 3.6e-17 62.3 13.7 3.6e-17 62.3 13.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.32 KER21828.1 - 3.4e-11 43.5 5.4 4e-05 24.3 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat IBR PF01485.21 KER21828.1 - 0.0069 16.6 6.8 0.0069 16.6 6.8 2.0 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 KER21828.1 - 0.38 11.0 10.2 0.94 9.7 10.2 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger Cluap1 PF10234.9 KER21829.1 - 2.2e-101 338.8 8.9 2.4e-101 338.6 7.6 1.7 1 1 0 1 1 1 1 Clusterin-associated protein-1 PBP1_TM PF14812.6 KER21829.1 - 0.01 16.2 2.9 0.01 16.2 2.9 2.7 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Afi1 PF07792.12 KER21829.1 - 0.012 16.1 0.9 6.9 7.2 4.8 3.2 3 2 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Imm49 PF15575.6 KER21829.1 - 0.033 13.9 1.3 0.12 12.2 0.8 1.9 1 1 1 2 2 2 0 Immunity protein 49 DUF1664 PF07889.12 KER21829.1 - 0.38 10.8 2.9 11 6.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.19 KER21829.1 - 1.4 9.6 8.9 3 8.5 5.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KER21829.1 - 1.9 8.9 17.3 0.23 11.9 11.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Atg14 PF10186.9 KER21829.1 - 4.1 6.4 12.3 0.86 8.6 8.1 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_fiss_reg PF05308.11 KER21829.1 - 6.2 6.8 8.3 12 5.9 2.7 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator MCU PF04678.13 KER21830.1 - 1.8e-65 220.3 0.4 2.3e-65 220.0 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Ribosomal_L29 PF00831.23 KER21830.1 - 0.12 12.4 0.5 0.39 10.7 0.5 1.9 1 0 0 1 1 1 0 Ribosomal L29 protein PRKG1_interact PF15898.5 KER21830.1 - 0.21 12.5 2.4 1.5 9.7 0.5 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Pkinase PF00069.25 KER21832.1 - 2.2e-31 109.2 0.0 4e-30 105.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21832.1 - 4.3e-15 55.7 0.0 4.9e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase POLO_box PF00659.18 KER21832.1 - 0.0003 20.9 0.0 0.00083 19.5 0.0 1.7 1 0 0 1 1 1 1 POLO box duplicated region Pkinase_fungal PF17667.1 KER21832.1 - 0.00036 19.4 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER21832.1 - 0.0025 17.2 0.0 0.9 8.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KER21832.1 - 0.039 13.9 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.17 KER21833.1 - 2.5e-55 188.1 9.5 1.2e-35 123.6 0.5 2.1 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase hDGE_amylase PF14701.6 KER21834.1 - 1.7e-133 445.9 0.0 2.4e-133 445.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KER21834.1 - 1e-101 340.7 0.0 2.1e-101 339.7 0.0 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KER21834.1 - 9e-77 258.2 0.0 1.4e-76 257.5 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KER21834.1 - 2e-15 56.7 0.1 3.8e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme GreA_GreB_N PF03449.15 KER21834.1 - 0.096 12.9 0.7 0.21 11.7 0.7 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF1870 PF08965.10 KER21834.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) 7tm_1 PF00001.21 KER21836.1 - 4.8e-12 45.8 10.2 8.5e-12 45.0 10.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER21836.1 - 0.0021 17.5 13.4 0.0039 16.6 13.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Yip1 PF04893.17 KER21837.1 - 0.001 18.8 4.0 0.001 18.8 4.0 1.1 1 0 0 1 1 1 1 Yip1 domain MFS_Mycoplasma PF07672.13 KER21837.1 - 0.0043 16.4 1.3 0.0047 16.3 1.3 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter TssN PF17555.2 KER21837.1 - 0.0047 16.4 1.9 0.0056 16.1 1.9 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssN DUF1218 PF06749.12 KER21837.1 - 0.01 16.3 4.0 0.093 13.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.6 KER21837.1 - 0.018 14.8 5.0 0.044 13.5 5.0 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EMP70 PF02990.16 KER21837.1 - 0.024 13.3 3.8 0.027 13.2 3.8 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4257 PF14074.6 KER21837.1 - 0.1 12.8 5.1 0.15 12.3 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF3040 PF11239.8 KER21837.1 - 0.15 12.3 3.1 1.3 9.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Rax2 PF12768.7 KER21837.1 - 0.18 11.2 0.1 0.18 11.2 0.1 1.5 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Amastin PF07344.11 KER21837.1 - 1.3 8.8 8.0 0.26 11.1 3.7 1.8 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF5305 PF17231.2 KER21837.1 - 1.4 8.3 5.1 1.8 7.9 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF4064 PF13273.6 KER21837.1 - 2.1 8.7 16.5 0.28 11.5 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 KER21837.1 - 3 6.5 7.1 1.1 7.9 4.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4229 PF14012.6 KER21838.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) TssN PF17555.2 KER21838.1 - 0.38 10.1 10.9 2.4 7.5 10.9 1.8 1 1 0 1 1 1 0 Type VI secretion system, TssN UPF0767 PF15990.5 KER21838.1 - 4.5 7.5 5.5 26 5.0 2.0 2.3 2 0 0 2 2 2 0 UPF0767 family Amastin PF07344.11 KER21838.1 - 4.9 7.0 16.2 0.077 12.8 8.0 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein ABC2_membrane_5 PF13346.6 KER21838.1 - 7.9 6.0 18.8 12 5.4 18.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Tmemb_185A PF10269.9 KER21839.1 - 0.019 14.7 1.3 3.8 7.1 0.3 2.1 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein Tad PF13400.6 KER21839.1 - 6.7 7.1 5.8 31 5.0 0.1 3.1 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Amastin PF07344.11 KER21840.1 - 0.00097 19.0 9.7 0.00097 19.0 9.7 2.3 1 1 1 2 2 2 1 Amastin surface glycoprotein PhoLip_ATPase_C PF16212.5 KER21840.1 - 1 9.0 16.6 1.5 8.5 16.6 1.2 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF2569 PF10754.9 KER21840.1 - 3.8 8.0 19.3 7.1 7.1 19.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF2070 PF09843.9 KER21840.1 - 4.7 5.4 19.0 5.5 5.2 19.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 KER21840.1 - 5.8 6.6 18.9 0.6 9.8 14.1 1.7 1 1 0 1 1 1 0 Tetraspanin family AhpC-TSA PF00578.21 KER21841.1 - 9.9e-27 93.3 0.0 1.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KER21841.1 - 1.2e-07 31.5 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AAA PF00004.29 KER21842.1 - 8.8e-93 307.7 0.0 2.9e-47 160.4 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER21842.1 - 4.4e-22 77.6 9.8 1.8e-11 43.7 1.8 3.5 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 KER21842.1 - 2e-19 69.6 0.3 5e-19 68.3 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KER21842.1 - 7.2e-14 51.8 0.0 7.6e-06 25.8 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KER21842.1 - 3.9e-12 46.6 0.0 3.7e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KER21842.1 - 5.4e-12 46.4 7.6 0.00016 22.1 0.1 5.2 4 2 1 5 5 4 2 AAA ATPase domain AAA_2 PF07724.14 KER21842.1 - 5.1e-10 39.7 0.0 2.7e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KER21842.1 - 9.5e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KER21842.1 - 1.4e-09 38.1 0.3 0.00053 20.0 0.1 3.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER21842.1 - 1.7e-09 38.1 0.2 0.04 14.2 0.0 4.1 2 2 2 4 4 3 2 AAA domain TIP49 PF06068.13 KER21842.1 - 1.6e-08 34.2 0.0 0.0016 17.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 KER21842.1 - 4.9e-08 32.8 0.2 6.3e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 KER21842.1 - 1.1e-07 32.5 0.0 0.025 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KER21842.1 - 1.8e-07 31.5 0.0 0.0049 17.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KER21842.1 - 4.2e-07 29.6 0.3 0.02 14.3 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KER21842.1 - 6.6e-07 29.4 0.0 0.056 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KER21842.1 - 1.2e-06 28.4 0.1 0.058 13.1 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 KER21842.1 - 2.4e-06 26.9 0.1 0.037 13.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KER21842.1 - 4.8e-06 26.9 0.2 0.16 12.2 0.0 3.1 3 1 1 4 4 2 2 AAA domain AAA_7 PF12775.7 KER21842.1 - 6.2e-06 25.8 0.0 0.071 12.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KER21842.1 - 8.3e-06 25.3 0.3 0.5 9.7 0.0 3.4 2 1 1 3 3 3 2 KaiC ATPase_2 PF01637.18 KER21842.1 - 9.4e-06 25.7 0.5 0.27 11.1 0.0 3.4 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KER21842.1 - 1.1e-05 26.0 0.0 0.017 15.7 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 KER21842.1 - 1.4e-05 24.8 0.3 1.7 8.1 0.0 3.4 2 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KER21842.1 - 2.4e-05 24.1 0.0 0.32 10.7 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KER21842.1 - 5.3e-05 23.0 0.0 0.12 12.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KER21842.1 - 7.3e-05 22.7 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 KER21842.1 - 9.1e-05 22.9 0.0 0.95 9.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KER21842.1 - 9.4e-05 22.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KER21842.1 - 0.0001 22.1 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KER21842.1 - 0.00011 21.5 0.0 0.085 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 KER21842.1 - 0.00013 21.9 0.1 0.34 10.8 0.0 3.6 3 1 0 4 4 4 1 NACHT domain NB-ARC PF00931.22 KER21842.1 - 0.00026 20.3 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ResIII PF04851.15 KER21842.1 - 0.00036 20.6 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KER21842.1 - 0.00043 20.4 0.0 1.9 8.6 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KER21842.1 - 0.00054 19.3 0.0 0.55 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.16 KER21842.1 - 0.001 18.6 0.2 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 KER21842.1 - 0.0012 18.1 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KER21842.1 - 0.0017 18.2 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KER21842.1 - 0.0022 17.8 0.2 2 8.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KER21842.1 - 0.0039 17.1 0.0 1.1 9.1 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_19 PF13245.6 KER21842.1 - 0.0056 17.0 0.9 3.6 7.9 0.2 3.1 2 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 KER21842.1 - 0.024 14.4 0.2 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KER21842.1 - 0.029 14.3 0.1 5.5 6.9 0.0 3.2 3 0 0 3 3 3 0 NTPase SKI PF01202.22 KER21842.1 - 0.079 13.1 0.0 8.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 KER21842.1 - 0.091 12.5 0.0 23 4.6 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 KER21842.1 - 0.15 11.8 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KER21842.1 - 0.17 11.5 0.0 11 5.6 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 KER21842.1 - 0.22 10.7 0.3 5.6 6.1 0.0 2.9 2 2 1 4 4 4 0 KAP family P-loop domain AAA_23 PF13476.6 KER21842.1 - 0.22 12.0 0.2 16 5.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain Dpy19 PF10034.9 KER21844.1 - 0.032 12.4 0.1 0.038 12.2 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Robl_LC7 PF03259.17 KER21845.1 - 2e-13 49.9 0.0 6.3e-13 48.3 0.0 1.7 1 1 1 2 2 2 1 Roadblock/LC7 domain CybS PF05328.12 KER21846.1 - 1.6e-24 86.1 0.1 1.8e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit FERM_N PF09379.10 KER21847.1 - 2e-09 37.2 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KER21847.1 - 2.4e-08 34.3 0.2 5.8e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KER21847.1 - 0.0018 18.7 0.0 0.0055 17.1 0.0 1.9 1 1 0 1 1 1 1 FERM central domain DUF2093 PF09866.9 KER21848.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Cyclin_N PF00134.23 KER21849.1 - 4.4e-08 32.9 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KER21849.1 - 2e-06 28.3 0.1 2.8e-06 27.8 0.1 1.4 1 1 0 1 1 1 1 Cyclin DUF2733 PF10813.8 KER21849.1 - 0.064 13.0 1.6 0.14 12.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DiSB-ORF2_chro PF16506.5 KER21849.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative virion glycoprotein of insect viruses Mago-bind PF09282.10 KER21853.1 - 1.8e-14 53.3 0.9 1.8e-14 53.3 0.9 2.0 3 0 0 3 3 3 1 Mago binding E2R135 PF11570.8 KER21853.1 - 0.00075 19.8 4.3 6.1 7.1 0.2 3.2 3 0 0 3 3 3 3 Coiled-coil receptor-binding R-domain of colicin E2 DUF3545 PF12065.8 KER21853.1 - 0.0071 16.3 1.0 0.0071 16.3 1.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3545) SPT6_acidic PF14632.6 KER21853.1 - 9.9 6.8 15.8 9.5 6.9 0.3 3.7 3 1 0 3 3 3 0 Acidic N-terminal SPT6 SAMP PF05924.11 KER21854.1 - 8.6e-15 53.5 14.7 0.00064 18.9 0.3 5.9 5 0 0 5 5 5 5 SAMP Motif Arm PF00514.23 KER21854.1 - 2.2e-13 49.8 21.5 0.0003 20.7 0.1 8.5 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat APC_r PF05923.12 KER21854.1 - 0.0052 16.5 18.6 0.51 10.1 0.5 6.3 5 0 0 5 5 5 2 APC repeat DUF383 PF04063.14 KER21854.1 - 0.028 14.1 0.5 0.067 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF3894 PF13033.6 KER21854.1 - 0.031 14.4 0.3 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) APC_rep PF18797.1 KER21854.1 - 0.039 14.9 0.0 0.13 13.2 0.0 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat Exonuc_VII_S PF02609.16 KER21854.1 - 0.12 12.5 2.9 6 7.0 0.2 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Tubulin PF00091.25 KER21857.1 - 1.8e-53 181.7 0.0 3.1e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER21857.1 - 4.8e-26 91.4 0.1 1.8e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Frizzled PF01534.17 KER21859.1 - 2.6e-127 424.3 3.7 4.6e-127 423.6 3.7 1.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KER21859.1 - 9.2e-15 55.2 0.3 2.2e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Fz domain Serpin PF00079.20 KER21862.1 - 3.1e-15 56.4 0.0 3.5e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 KER21863.1 - 1.2e-20 74.2 0.0 1.2e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pou PF00157.17 KER21865.1 - 1.6e-37 127.3 0.4 1.6e-22 79.3 0.1 2.9 3 0 0 3 3 3 2 Pou domain - N-terminal to homeobox domain HTH_31 PF13560.6 KER21865.1 - 0.013 15.9 0.6 0.84 10.0 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain YqzH PF14164.6 KER21865.1 - 0.16 12.0 0.0 12 6.1 0.0 2.6 3 0 0 3 3 3 0 YqzH-like protein DUF963 PF06131.11 KER21865.1 - 1.2 8.6 6.0 13 5.3 0.6 2.7 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) RVT_1 PF00078.27 KER21866.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) FAT PF02259.23 KER21867.1 - 3.3e-73 246.9 0.0 7.4e-62 209.6 0.0 2.5 2 0 0 2 2 2 2 FAT domain PI3_PI4_kinase PF00454.27 KER21867.1 - 1e-69 235.2 0.4 1.9e-69 234.2 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KER21867.1 - 4.8e-42 143.6 0.3 1.9e-40 138.4 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KER21867.1 - 1.9e-32 111.6 0.7 8e-32 109.6 0.7 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 KER21867.1 - 2.3e-10 40.1 0.1 5.6e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KER21867.1 - 3.4e-07 30.5 1.1 0.047 14.1 0.0 5.8 6 0 0 6 6 5 2 HEAT repeats HEAT PF02985.22 KER21867.1 - 1.1e-05 25.3 15.0 1.9 8.9 0.1 8.8 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 KER21867.1 - 2.5e-05 24.7 6.7 0.081 13.4 0.0 7.7 6 1 1 7 7 7 2 HEAT-like repeat TPR_19 PF14559.6 KER21867.1 - 0.018 15.5 0.6 2.1 8.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KER21867.1 - 0.068 14.0 3.5 0.6 11.1 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER21867.1 - 0.42 10.9 2.5 18 5.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 KER21869.1 - 1.3e-12 47.3 6.0 1.7e-12 46.9 6.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER21869.1 - 3.4e-08 32.5 9.5 3.9e-08 32.3 9.5 1.0 1 0 0 1 1 1 1 Amino acid permease Trep_Strep PF09605.10 KER21869.1 - 4.8e-05 23.4 4.5 6.3e-05 23.0 4.5 1.1 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) UCR_6-4kD PF08997.10 KER21869.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein AA_permease_2 PF13520.6 KER21870.1 - 1e-28 100.4 17.3 1e-28 100.4 17.3 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KER21870.1 - 8.5e-19 67.5 19.8 8.5e-19 67.5 19.8 2.2 2 1 1 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 KER21870.1 - 2.7e-14 53.0 3.0 2.7e-14 53.0 3.0 3.8 3 0 0 3 3 3 1 C-terminus of AA_permease DUF751 PF05421.11 KER21870.1 - 2.4 9.0 9.3 0.2 12.4 1.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF751) Ski_Sno PF02437.17 KER21872.1 - 4.9e-32 109.9 0.1 1.3e-31 108.6 0.1 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KER21872.1 - 1.7e-24 85.8 0.5 4.1e-24 84.6 0.5 1.6 1 0 0 1 1 1 1 c-SKI Smad4 binding domain Cas9_REC PF16592.5 KER21872.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 Flavin_Reduct PF01613.18 KER21873.1 - 0.1 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Flavin reductase like domain MORN PF02493.20 KER21878.1 - 0.00019 21.1 16.6 0.01 15.7 3.7 4.9 5 1 0 5 5 5 2 MORN repeat eIF-5a PF01287.20 KER21879.1 - 8.3e-17 61.1 0.1 1.4e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KER21879.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RhoGEF PF00621.20 KER21881.1 - 9.4e-21 74.9 0.0 2.4e-20 73.6 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain AMPK1_CBM PF16561.5 KER21883.1 - 5.6e-34 116.2 0.5 9e-34 115.6 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KER21883.1 - 1.3e-24 86.2 1.7 2.5e-24 85.3 1.7 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 KER21883.1 - 0.0034 17.9 0.1 0.0062 17.1 0.1 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 KER21883.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DSPc PF00782.20 KER21884.1 - 9.5e-32 109.6 0.0 1.4e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER21884.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KER21884.1 - 0.0049 17.2 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KER21884.1 - 0.058 13.5 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate ABC_tran PF00005.27 KER21885.1 - 1.5e-16 61.2 0.0 2.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF1151 PF06625.11 KER21885.1 - 0.0067 16.4 0.8 0.014 15.4 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) AAA_16 PF13191.6 KER21885.1 - 0.036 14.4 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SapC PF07277.11 KER21885.1 - 0.055 13.1 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 SapC PAS_3 PF08447.12 KER21886.1 - 1.1e-09 38.5 0.0 2.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KER21886.1 - 0.034 14.3 0.1 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain Med31 PF05669.12 KER21887.1 - 1.1e-36 124.8 4.8 1.3e-36 124.5 4.8 1.1 1 0 0 1 1 1 1 SOH1 RnfC_N PF13375.6 KER21888.1 - 0.012 15.6 0.0 3.4 7.7 0.0 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Ldt_C PF17969.1 KER21888.1 - 0.019 15.7 0.0 8.2 7.2 0.0 2.4 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain DUF3652 PF12372.8 KER21888.1 - 0.16 11.9 0.2 17 5.4 0.0 2.6 2 1 0 2 2 2 0 Huntingtin protein region C5HCH PF17982.1 KER21888.1 - 0.17 12.1 3.5 9.3 6.5 0.3 2.2 2 0 0 2 2 2 0 NSD Cys-His rich domain RPEL PF02755.15 KER21888.1 - 0.25 11.1 0.6 31 4.4 0.1 2.5 2 0 0 2 2 2 0 RPEL repeat FAP206 PF12018.8 KER21890.1 - 4.1e-67 226.6 0.0 5.4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function A_deaminase PF00962.22 KER21891.1 - 5.6e-08 32.5 0.0 7.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Gp138_N PF18352.1 KER21891.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Phage protein Gp138 N-terminal domain GTP_EFTU PF00009.27 KER21894.1 - 1.2e-42 145.7 0.0 2e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KER21894.1 - 2.6e-07 30.6 0.0 5.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KER21894.1 - 4.5e-06 26.6 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KER21894.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV SRPRB PF09439.10 KER21894.1 - 0.018 14.5 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TrmO_C PF18389.1 KER21894.1 - 0.053 13.6 1.2 5.9 7.1 0.1 3.4 2 1 1 3 3 3 0 TrmO C-terminal domain GTP_EFTU_D2 PF03144.25 KER21894.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 PK PF00224.21 KER21896.1 - 1.4e-87 293.9 0.0 1.7e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KER21896.1 - 2.3e-26 92.3 0.2 8.5e-26 90.5 0.1 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Cpn60_TCP1 PF00118.24 KER21898.1 - 2.8e-157 524.3 1.1 3.4e-157 524.0 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myotub-related PF06602.14 KER21899.1 - 2.9e-118 394.8 0.0 3.9e-118 394.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 KER21899.1 - 0.0034 17.2 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER21899.1 - 0.0034 17.4 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.16 KER21899.1 - 0.0038 17.4 2.4 0.0038 17.4 2.4 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Y_phosphatase PF00102.27 KER21899.1 - 0.021 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IBR PF01485.21 KER21899.1 - 0.058 13.6 1.2 0.19 12.0 1.2 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE PF01363.21 KER21899.1 - 1.3 9.3 15.6 0.049 13.8 7.7 2.5 2 1 0 2 2 2 0 FYVE zinc finger RVT_1 PF00078.27 KER21900.1 - 1.6e-11 44.1 0.3 1.6e-10 40.9 0.3 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 KER21900.1 - 0.0013 18.2 2.3 0.0013 18.2 2.3 1.9 2 0 0 2 2 2 1 BUD22 DNA_pol_phi PF04931.13 KER21900.1 - 0.0016 16.6 23.8 0.0016 16.6 23.8 2.1 3 0 0 3 3 3 1 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 KER21900.1 - 0.0031 17.8 13.6 0.0031 17.8 13.6 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 KER21900.1 - 0.11 11.7 35.3 0.21 10.7 35.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NSP2-B_epitope PF14757.6 KER21900.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein CNDH2_C PF16858.5 KER21900.1 - 0.23 11.3 5.5 0.4 10.5 5.3 1.6 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AI-2E_transport PF01594.16 KER21900.1 - 0.34 10.0 0.1 0.71 9.0 0.1 1.5 1 0 0 1 1 1 0 AI-2E family transporter Mpp10 PF04006.12 KER21900.1 - 0.59 8.5 12.5 1 7.7 12.5 1.3 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 KER21900.1 - 1.1 8.6 13.3 1.8 7.9 13.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KER21900.1 - 1.9 6.6 18.6 3.2 5.9 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KER21900.1 - 3.1 7.2 20.2 5.1 6.4 20.2 1.2 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KER21900.1 - 5.1 6.2 8.2 10 5.2 8.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.13 KER21900.1 - 5.8 6.7 21.5 2.3 8.1 16.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PPP4R2 PF09184.11 KER21900.1 - 7.8 6.0 21.8 0.43 10.1 16.4 1.7 2 1 0 2 2 2 0 PPP4R2 RED_N PF07808.13 KER21901.1 - 3.8e-86 288.5 4.8 8.7e-86 287.3 4.8 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region RED_C PF07807.11 KER21901.1 - 3e-53 179.1 3.3 3e-53 179.1 3.3 2.6 3 0 0 3 3 3 1 RED-like protein C-terminal region Lsm_interact PF05391.11 KER21901.1 - 0.0036 16.7 1.1 0.0036 16.7 1.1 2.0 2 0 0 2 2 2 1 Lsm interaction motif RNase_H PF00075.24 KER21902.1 - 1e-34 119.7 0.1 2.3e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 RNase H PGM_PMM_I PF02878.16 KER21902.1 - 4.1e-28 97.8 0.0 9.2e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KER21902.1 - 4e-26 91.5 0.0 8.5e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KER21902.1 - 2.1e-10 41.2 0.1 9.3e-10 39.1 0.0 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KER21902.1 - 2.2e-05 24.5 0.0 7.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RVT_3 PF13456.6 KER21902.1 - 0.00086 19.1 0.1 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase-like DUF4517 PF15006.6 KER21903.1 - 2.9e-28 99.0 0.0 4.4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) Thioredoxin_16 PF18569.1 KER21907.1 - 0.12 12.5 0.2 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like domain V-SNARE_C PF12352.8 KER21911.1 - 0.00027 21.2 9.3 0.054 13.8 1.0 2.6 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 KER21911.1 - 0.0003 20.7 4.1 0.39 10.6 0.3 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF5089) Nup88 PF10168.9 KER21911.1 - 0.0052 14.7 0.7 0.0052 14.7 0.7 1.5 2 0 0 2 2 2 1 Nuclear pore component SlyX PF04102.12 KER21911.1 - 0.038 14.6 5.7 5.9 7.6 0.0 3.1 3 1 0 3 3 3 0 SlyX NPV_P10 PF05531.12 KER21911.1 - 0.043 14.3 0.2 0.78 10.3 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KER21911.1 - 0.069 13.6 1.4 0.41 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 HemX PF04375.14 KER21911.1 - 0.11 11.7 7.4 0.95 8.7 1.8 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase XhlA PF10779.9 KER21911.1 - 0.39 10.9 2.4 5.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA UPF0242 PF06785.11 KER21911.1 - 0.58 10.2 6.2 0.22 11.6 0.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YlqD PF11068.8 KER21911.1 - 0.63 10.4 5.7 1.9 8.9 0.4 2.2 2 0 0 2 2 2 0 YlqD protein Tho2 PF11262.8 KER21911.1 - 0.77 8.9 2.7 1.3 8.1 0.2 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 WD40 PF00400.32 KER21912.1 - 1.1e-09 38.7 1.4 0.0053 17.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KER21912.1 - 0.033 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Dus PF01207.17 KER21913.1 - 8.5e-48 163.0 0.1 1.5e-47 162.2 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KER21913.1 - 0.032 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain SOR_SNZ PF01680.17 KER21913.1 - 0.056 13.2 1.2 0.16 11.7 0.0 2.2 2 1 1 3 3 3 0 SOR/SNZ family Tma16 PF11176.8 KER21914.1 - 4.8e-24 84.9 5.4 7e-23 81.1 5.4 1.9 1 1 0 1 1 1 1 Translation machinery-associated protein 16 DUF5513 PF17632.2 KER21914.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5513) Pkinase PF00069.25 KER21915.1 - 5.3e-122 406.3 0.0 1.7e-73 247.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER21915.1 - 5.1e-63 212.8 0.0 3.7e-35 121.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER21915.1 - 3.4e-11 43.0 0.0 3.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KER21915.1 - 4.1e-08 32.8 0.3 0.0025 17.2 0.1 2.5 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER21915.1 - 1e-07 32.2 0.9 0.31 10.9 0.1 3.7 3 1 1 4 4 4 3 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KER21915.1 - 1.8e-07 30.3 0.0 0.002 17.0 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KER21915.1 - 2.7e-06 27.0 0.0 0.0014 18.2 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pkinase_C PF00433.24 KER21915.1 - 6.4e-05 23.6 0.7 0.00055 20.6 0.8 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain RIO1 PF01163.22 KER21915.1 - 0.00011 21.9 0.5 0.007 16.0 0.1 2.2 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 KER21915.1 - 0.024 14.2 0.1 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KER21915.1 - 0.13 11.2 0.1 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KER21915.1 - 0.16 11.5 0.0 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase UCH PF00443.29 KER21917.1 - 3.6e-34 118.4 0.7 4.1e-34 118.2 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KER21917.1 - 2.3e-13 50.3 1.7 5.3e-13 49.1 1.7 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KER21917.1 - 0.0004 20.1 0.2 0.0011 18.6 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KER21917.1 - 0.17 11.6 1.3 0.45 10.3 1.3 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger Clathrin_lg_ch PF01086.17 KER21918.1 - 3.5e-18 66.5 1.9 6e-18 65.7 1.9 1.4 1 1 0 1 1 1 1 Clathrin light chain T2SSJ PF11612.8 KER21919.1 - 0.0025 18.0 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J MMR_HSR1_Xtn PF16897.5 KER21921.1 - 2.4e-36 124.0 0.6 1.3e-35 121.6 0.6 1.9 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KER21921.1 - 1.1e-21 77.1 0.0 2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER21921.1 - 9.9e-13 47.9 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KER21921.1 - 0.00011 22.4 1.2 0.24 11.4 0.2 2.9 1 1 2 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KER21921.1 - 0.0062 16.5 0.2 0.24 11.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 KER21921.1 - 0.011 16.0 0.2 0.031 14.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KER21921.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 KER21921.1 - 0.046 14.0 0.3 0.51 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KER21921.1 - 0.11 11.5 0.0 0.28 10.1 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 KER21921.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KER21922.1 - 0.032 14.8 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KER21922.1 - 0.042 14.2 0.0 0.37 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain FIST_C PF10442.9 KER21922.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FIST C domain AAA_5 PF07728.14 KER21922.1 - 0.098 12.7 0.1 0.31 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KER21922.1 - 0.11 12.8 0.2 1.8 8.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain ATG16 PF08614.11 KER21922.1 - 0.18 12.0 9.8 0.7 10.1 9.8 2.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Swi5 PF07061.11 KER21922.1 - 0.62 10.2 2.9 1.7 8.8 2.9 1.8 1 0 0 1 1 1 0 Swi5 Phasin PF05597.11 KER21922.1 - 1.1 9.3 2.9 2.3 8.2 2.9 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4407 PF14362.6 KER21922.1 - 5.9 6.2 8.1 11 5.2 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AMMECR1 PF01871.17 KER21924.1 - 1.4e-08 34.5 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.25 KER21925.1 - 3.6e-61 206.8 0.0 7.1e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21925.1 - 4.2e-31 108.2 0.0 7.4e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER21925.1 - 3.7e-07 29.7 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER21925.1 - 0.00018 20.5 0.2 0.00056 19.0 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KER21925.1 - 0.00088 19.3 0.0 0.00088 19.3 0.0 3.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family C1_1 PF00130.22 KER21925.1 - 0.0015 18.4 8.0 0.0039 17.0 8.0 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Abi_HHR PF07815.14 KER21925.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Abl-interactor HHR Pkinase_C PF00433.24 KER21925.1 - 0.19 12.5 2.3 0.77 10.5 2.3 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain EspB_PE PF18625.1 KER21926.1 - 1.3 9.6 4.6 11 6.6 0.0 4.3 4 0 0 4 4 4 0 ESX-1 secreted protein B PE domain FERM_C PF09380.10 KER21928.1 - 4.2e-07 30.2 2.5 4.2e-06 27.0 3.2 2.1 2 0 0 2 2 2 1 FERM C-terminal PH-like domain RVT_1 PF00078.27 KER21928.1 - 1.2e-06 28.2 0.0 2.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IQ PF00612.27 KER21928.1 - 0.34 10.8 1.1 1.1 9.2 1.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif RVT_1 PF00078.27 KER21929.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cation_efflux PF01545.21 KER21931.1 - 6.2e-24 84.8 6.0 3.3e-17 62.9 1.2 2.1 1 1 1 2 2 2 2 Cation efflux family Peptidase_C13 PF01650.18 KER21934.1 - 0.00015 21.4 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family FtsH_ext PF06480.15 KER21934.1 - 7.1 7.0 17.3 1.8e+04 -10.0 17.3 5.5 1 1 0 1 1 1 0 FtsH Extracellular Peptidase_C13 PF01650.18 KER21935.1 - 6.8e-104 346.9 5.3 3.6e-82 275.7 1.6 2.1 2 0 0 2 2 2 2 Peptidase C13 family Pentapeptide_4 PF13599.6 KER21935.1 - 2.9e-07 30.5 3.0 5.9e-07 29.6 3.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Peptidase_C14 PF00656.22 KER21935.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Caspase domain PT PF04886.12 KER21936.1 - 5.4e-17 61.0 41.1 5.1e+03 -2.9 1.2 6.0 2 1 0 2 2 2 0 PT repeat Peptidase_C13 PF01650.18 KER21938.1 - 2e-88 296.2 1.9 2.8e-88 295.7 1.9 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER21938.1 - 0.0018 18.3 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER21938.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C25 Peptidase_C13 PF01650.18 KER21939.1 - 4.2e-06 26.5 0.1 5.4e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family tRNA-synt_1e PF01406.19 KER21940.1 - 3.4e-91 305.8 0.0 5.1e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KER21940.1 - 0.00045 19.1 0.1 0.00073 18.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KER21940.1 - 0.012 13.9 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) RNase_P_pop3 PF08228.11 KER21940.1 - 0.032 14.3 0.0 0.081 13.0 0.0 1.7 1 0 0 1 1 1 0 RNase P subunit Pop3 Aldolase PF01081.19 KER21941.1 - 1e-06 28.3 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 2 KDPG and KHG aldolase Lsr2 PF11774.8 KER21941.1 - 0.039 14.1 0.9 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Lsr2 PGA2 PF07543.12 KER21941.1 - 0.058 13.4 0.1 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 PEGSRP PF07623.11 KER21941.1 - 0.34 10.7 1.7 25 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) WW_FCH_linker PF16623.5 KER21941.1 - 0.81 10.5 4.4 24 5.7 0.4 2.4 2 0 0 2 2 2 0 Unstructured linker region between on GAS7 protein Ank_4 PF13637.6 KER21942.1 - 2e-28 98.4 5.2 2.6e-12 47.0 0.2 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER21942.1 - 2.5e-23 82.5 2.3 3.6e-13 49.9 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER21942.1 - 1.3e-18 65.1 1.4 0.00014 22.0 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KER21942.1 - 9e-18 64.1 1.2 5.1e-09 36.2 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KER21942.1 - 9.3e-16 57.5 2.4 0.019 15.4 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat WAK_assoc PF14380.6 KER21943.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.7 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal Ank_2 PF12796.7 KER21944.1 - 3e-47 159.1 7.4 2.1e-12 47.4 0.1 7.1 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER21944.1 - 4.2e-43 145.2 3.6 2e-10 41.0 0.0 8.2 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21944.1 - 2.2e-36 119.7 9.8 0.0001 22.4 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KER21944.1 - 4.5e-36 121.7 13.4 1.1e-05 25.7 0.1 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KER21944.1 - 7.8e-33 112.1 13.5 7.7e-08 32.5 0.1 9.1 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ion_trans PF00520.31 KER21945.1 - 4e-06 26.2 13.1 7.9e-06 25.3 13.1 1.4 1 0 0 1 1 1 1 Ion transport protein UPF0182 PF03699.13 KER21945.1 - 3.3 5.7 10.4 8 4.4 10.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) MOZART1 PF12554.8 KER21946.1 - 0.4 10.5 1.9 12 5.8 0.2 2.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated LIN37 PF15306.6 KER21947.1 - 3.2e-30 105.4 0.0 2.1e-27 96.3 0.0 2.5 1 1 0 1 1 1 1 LIN37 RT_RNaseH_2 PF17919.1 KER21947.1 - 9.9e-29 99.3 0.0 2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER21947.1 - 5.1e-24 84.6 0.0 9.5e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KER21947.1 - 1.4e-05 25.6 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KER21947.1 - 0.00026 21.5 0.0 0.00061 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 KER21947.1 - 0.00058 19.9 0.5 0.002 18.2 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KER21948.1 - 9.8e-19 67.6 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER21948.1 - 1.1e-14 54.3 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pre-PUA PF17832.1 KER21949.1 - 5.5e-22 78.2 0.0 7.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KER21949.1 - 4.7e-18 64.9 0.1 1.3e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 PUA domain G-7-MTase PF12803.7 KER21949.1 - 0.09 11.9 0.0 3.3 6.8 0.0 2.0 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Glyco_transf_7C PF02709.14 KER21950.1 - 2.4e-22 78.4 0.3 5.9e-22 77.1 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KER21950.1 - 3.5e-19 68.8 0.1 3.8e-18 65.4 0.1 2.2 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 KER21950.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATG101 PF07855.12 KER21952.1 - 5.3e-19 68.7 0.0 7.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 101 RPAP1_N PF08621.10 KER21952.1 - 0.054 13.3 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal RNA_pol_Rpb2_7 PF04560.20 KER21953.1 - 0.036 14.5 0.0 0.094 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Tetraspanin PF00335.20 KER21954.1 - 1.5e-36 126.2 5.1 2.6e-36 125.5 5.1 1.3 1 0 0 1 1 1 1 Tetraspanin family AA_permease_2 PF13520.6 KER21955.1 - 3.2e-62 210.8 39.0 3.6e-62 210.6 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER21955.1 - 1.2e-30 106.6 36.1 1.7e-30 106.1 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease SirB PF04247.12 KER21955.1 - 0.45 10.6 0.1 0.45 10.6 0.1 3.3 4 0 0 4 4 4 0 Invasion gene expression up-regulator, SirB AA_permease_2 PF13520.6 KER21956.1 - 3.3e-61 207.4 45.9 4.6e-61 206.9 45.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER21956.1 - 3.4e-29 101.8 41.2 5.2e-29 101.2 41.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4257 PF14074.6 KER21957.1 - 0.0019 18.3 0.5 2.5 8.4 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4257) DUF3382 PF11862.8 KER21957.1 - 0.021 15.1 2.7 0.83 10.0 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) COX3 PF00510.18 KER21957.1 - 0.022 14.6 7.1 0.041 13.7 1.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase subunit III IncF PF17626.2 KER21957.1 - 0.13 12.6 1.1 16 5.9 0.1 2.3 1 1 1 2 2 2 0 Inclusion membrane protein F AA_permease_2 PF13520.6 KER21958.1 - 4.2e-07 29.1 0.7 5e-07 28.9 0.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER21958.1 - 5e-06 25.4 0.2 5.6e-06 25.2 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Parvo_coat PF00740.18 KER21958.1 - 0.08 11.6 0.0 0.084 11.5 0.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 AMP-binding PF00501.28 KER21958.1 - 0.2 10.2 0.8 0.23 10.0 0.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme AA_permease_2 PF13520.6 KER21959.1 - 4.3e-41 141.2 19.0 4.7e-41 141.0 19.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER21959.1 - 3.4e-20 72.1 16.6 4.1e-20 71.8 16.6 1.0 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KER21959.1 - 6.8e-05 21.7 12.3 8.8e-05 21.4 12.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PMP22_Claudin PF00822.20 KER21959.1 - 0.0082 16.0 4.8 0.015 15.2 0.3 2.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family 7TMR-DISM_7TM PF07695.11 KER21959.1 - 0.009 15.9 3.7 0.009 15.9 3.7 2.9 2 1 0 3 3 3 1 7TM diverse intracellular signalling DUF5373 PF17343.2 KER21959.1 - 0.066 13.0 8.8 0.22 11.3 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5373) RNase_T PF00929.24 KER21960.1 - 6.1e-15 56.2 0.0 8.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF4756 PF15948.5 KER21960.1 - 0.025 14.4 0.2 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) DNA_pol_A_exo1 PF01612.20 KER21960.1 - 0.074 12.8 0.0 1.1 8.9 0.0 2.4 1 1 0 1 1 1 0 3'-5' exonuclease CotJB PF12652.7 KER21960.1 - 0.25 11.6 0.3 0.7 10.2 0.0 1.9 2 0 0 2 2 2 0 CotJB protein Spt5-NGN PF03439.13 KER21962.1 - 1.8e-25 88.6 0.1 3.6e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KER21962.1 - 1.6e-16 59.6 8.0 0.00016 21.5 0.0 6.8 7 0 0 7 7 7 4 KOW motif Spt5_N PF11942.8 KER21962.1 - 1.9e-08 35.2 18.6 1.9e-08 35.2 18.6 1.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.32 KER21962.1 - 1.3e-06 29.0 2.0 0.00011 22.9 0.3 3.7 2 0 0 2 2 2 1 WD domain, G-beta repeat TPR_1 PF00515.28 KER21964.1 - 2.5e-17 61.9 0.1 3e-05 23.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 KER21964.1 - 1.4e-16 60.8 0.1 4.5e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 KER21964.1 - 8.5e-15 53.6 0.9 0.0017 18.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KER21964.1 - 2.9e-09 36.9 0.5 3.1e-06 27.2 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER21964.1 - 3.2e-09 36.3 0.0 1.6e-06 27.7 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 KER21964.1 - 7.1e-09 35.2 0.1 0.014 15.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER21964.1 - 1.1e-08 35.6 0.9 3.9e-06 27.4 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER21964.1 - 1.1e-05 25.9 1.1 0.28 12.1 0.0 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER21964.1 - 6.7e-05 22.6 0.6 0.057 13.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER21964.1 - 7.4e-05 23.2 0.2 0.034 14.7 0.1 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER21964.1 - 0.00011 22.3 0.3 0.11 13.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER21964.1 - 0.00013 22.3 0.0 0.016 15.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER21964.1 - 0.00043 20.5 2.7 1 9.7 2.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER21964.1 - 0.048 13.7 0.5 6.7 6.9 0.2 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 KER21964.1 - 0.055 12.9 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Ly49 PF08391.10 KER21964.1 - 0.068 13.5 1.5 0.092 13.1 0.6 1.6 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region PP-binding_2 PF14573.6 KER21964.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Acyl-carrier NOP19 PF10863.8 KER21964.1 - 2.1 8.2 6.4 4 7.3 0.1 2.8 2 1 1 3 3 3 0 Nucleolar protein 19 DUF1979 PF09322.10 KER21965.1 - 0.048 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Peroxidase_ext PF11895.8 KER21965.1 - 0.055 13.4 0.3 28 4.7 0.1 3.2 3 0 0 3 3 3 0 Fungal peroxidase extension region DUF1840 PF08895.11 KER21965.1 - 0.15 12.4 0.0 45 4.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) End_tail_spike PF12219.8 KER21965.1 - 0.15 12.1 0.0 29 4.7 0.0 2.3 2 0 0 2 2 2 0 Catalytic domain of bacteriophage endosialidase Activin_recp PF01064.23 KER21965.1 - 0.62 11.2 3.9 11 7.2 1.1 2.5 2 0 0 2 2 2 0 Activin types I and II receptor domain Hat1_N PF10394.9 KER21966.1 - 6e-21 75.3 0.3 9.9e-21 74.6 0.3 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KER21966.1 - 0.075 13.3 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family LIM_bind PF01803.16 KER21966.1 - 0.13 11.8 0.7 0.47 9.9 0.6 1.9 2 0 0 2 2 2 0 LIM-domain binding protein TPD52 PF04201.15 KER21967.1 - 0.036 13.7 0.3 0.039 13.6 0.3 1.1 1 0 0 1 1 1 0 Tumour protein D52 family PAX PF00292.18 KER21969.1 - 2.3e-63 211.7 1.4 5.6e-63 210.5 0.3 1.9 2 0 0 2 2 2 1 'Paired box' domain Homeodomain PF00046.29 KER21969.1 - 2.2e-13 49.8 2.8 2.7e-13 49.5 0.6 2.3 2 0 0 2 2 2 1 Homeodomain HTH_23 PF13384.6 KER21969.1 - 0.00042 20.0 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KER21969.1 - 0.011 15.3 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain GPI2 PF06432.11 KER21969.1 - 0.22 10.9 1.3 8.9 5.7 0.2 2.3 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase SUIM_assoc PF16619.5 KER21969.1 - 0.74 9.9 9.7 1.4 9.0 5.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Folate_rec PF03024.14 KER21970.1 - 1.7e-41 142.0 23.1 2.2e-41 141.6 23.1 1.1 1 0 0 1 1 1 1 Folate receptor family DUF2066 PF09839.9 KER21970.1 - 0.099 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Lenti_VIF_2 PF07401.12 KER21970.1 - 0.15 11.4 2.8 0.15 11.4 1.6 1.6 2 0 0 2 2 2 0 Bovine Lentivirus VIF protein Ank_2 PF12796.7 KER21971.1 - 1.3e-08 35.3 0.1 0.00068 20.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER21971.1 - 7.2e-08 32.6 0.3 0.001 19.3 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER21971.1 - 9.4e-07 29.3 0.2 1.6e-05 25.3 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER21971.1 - 2.7e-05 24.2 0.7 0.63 10.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KER21971.1 - 3.6e-05 24.0 0.4 0.28 11.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 KER21971.1 - 0.12 12.7 0.9 0.3 11.4 0.9 1.7 1 0 0 1 1 1 0 Caulimovirus viroplasmin UTP25 PF06862.12 KER21972.1 - 1.2e-108 363.9 0.0 8.2e-75 252.4 0.0 3.0 2 1 1 3 3 3 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KER21972.1 - 0.087 12.6 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Peptidase_M8 PF01457.16 KER21973.1 - 4.2e-47 161.0 0.9 2.6e-43 148.5 0.0 3.6 2 1 1 3 3 3 2 Leishmanolysin Peptidase_C13 PF01650.18 KER21975.1 - 8e-100 333.6 8.5 6.2e-91 304.4 3.5 2.1 1 1 1 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER21975.1 - 0.00088 19.3 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 Caspase domain Sulfotransfer_3 PF13469.6 KER21975.1 - 0.09 13.1 0.2 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 Sulfotransferase family PheRS_DBD2 PF18554.1 KER21975.1 - 0.14 12.2 2.2 11 6.1 0.0 3.6 4 0 0 4 4 4 0 PheRS DNA binding domain 2 Peptidase_C13 PF01650.18 KER21977.1 - 3.8e-94 315.0 2.1 5.6e-94 314.4 2.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Sulfotransfer_3 PF13469.6 KER21977.1 - 0.071 13.5 1.0 1.7 9.0 0.0 2.6 2 1 0 3 3 3 0 Sulfotransferase family Peptidase_C14 PF00656.22 KER21977.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Caspase domain SBD_N PF07005.11 KER21977.1 - 0.21 11.3 0.8 7.6 6.2 0.1 2.4 1 1 1 2 2 2 0 Sugar-binding N-terminal domain Peptidase_C13 PF01650.18 KER21978.1 - 1e-75 254.6 2.8 1e-68 231.6 0.8 2.1 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER21978.1 - 0.00036 20.6 0.1 0.00048 20.1 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER21978.1 - 0.078 12.1 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C25 fn3 PF00041.21 KER21979.1 - 1.2e-33 115.3 7.0 3.9e-13 49.5 0.1 3.7 3 0 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER21979.1 - 6.5e-10 39.5 2.9 0.075 13.6 0.1 4.2 3 1 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KER21979.1 - 7.1e-06 26.1 0.5 7.1e-05 22.9 0.0 2.9 4 0 0 4 4 4 1 Fibronectin type III domain SusE PF14292.6 KER21979.1 - 0.00052 20.2 0.1 14 6.0 0.0 3.8 4 0 0 4 4 4 1 SusE outer membrane protein Arylsulfotran_N PF17425.2 KER21979.1 - 0.0021 18.0 0.2 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 Arylsulfotransferase Ig-like domain Interfer-bind PF09294.10 KER21979.1 - 0.0073 16.6 0.5 25 5.2 0.0 3.8 3 1 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 KER21979.1 - 0.034 14.5 0.0 15 6.1 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Hist_deacetyl PF00850.19 KER21980.1 - 1.7e-82 277.4 0.0 2.4e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 KER21981.1 - 4.2e-14 52.5 0.0 5.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21981.1 - 1.2e-09 37.9 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KER21981.1 - 0.065 13.4 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC1 family CNH PF00780.22 KER21982.1 - 1.9e-49 168.8 0.0 2.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 KER21982.1 - 1.7e-22 80.1 0.0 3.2e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER21982.1 - 5.5e-14 52.1 0.0 1.4e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Acylphosphatase PF00708.18 KER21983.1 - 7.1e-14 52.0 0.3 4.2e-13 49.5 0.3 1.8 1 1 0 1 1 1 1 Acylphosphatase Acetyltransf_4 PF13420.7 KER21983.1 - 0.075 13.2 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 KER21984.1 - 1.4e-43 148.7 0.0 5.8e-43 146.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KER21984.1 - 1.6e-27 96.0 0.3 5.2e-27 94.4 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KER21984.1 - 0.00011 22.6 0.0 0.00035 20.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KER21984.1 - 0.0022 18.1 0.0 0.01 15.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 KER21984.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 EF-hand_1 PF00036.32 KER21986.1 - 1.4e-23 80.6 4.4 0.0009 18.6 0.0 5.5 5 0 0 5 5 5 5 EF hand EF-hand_5 PF13202.6 KER21986.1 - 4.4e-21 73.4 6.2 0.00017 21.0 0.0 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KER21986.1 - 5.2e-19 68.5 14.7 5.4e-08 33.2 0.7 3.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KER21986.1 - 5.3e-19 66.5 6.7 0.00014 21.5 0.1 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KER21986.1 - 3.4e-11 42.8 9.6 0.024 14.5 0.2 5.3 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER21986.1 - 2.7e-06 27.7 9.8 0.01 16.2 0.6 3.5 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region AftA_N PF12250.8 KER21986.1 - 0.22 10.2 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Adap_comp_sub PF00928.21 KER21988.1 - 2e-48 165.1 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ERO1 PF04137.15 KER21990.1 - 5.1e-105 351.5 0.0 9.7e-105 350.6 0.0 1.4 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PseudoU_synth_1 PF01416.20 KER21991.1 - 1.3e-30 106.1 0.0 7.9e-28 97.1 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase cNMP_binding PF00027.29 KER21992.1 - 1.5e-40 137.2 0.1 1.2e-14 54.1 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KER21992.1 - 3.3e-19 69.9 0.0 1e-18 68.3 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4916 PF16262.5 KER21994.1 - 0.061 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) RPN1_RPN2_N PF17781.1 KER21995.1 - 2.9e-112 375.1 0.5 5.3e-112 374.2 0.5 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KER21995.1 - 3.5e-29 100.6 0.1 6.9e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KER21995.1 - 1.3e-14 53.7 24.3 0.00029 21.1 0.1 9.8 11 0 0 11 11 11 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KER21995.1 - 0.075 13.4 1.9 14 6.2 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats Dict-STAT-coil PF09267.10 KER21996.1 - 0.24 11.8 0.5 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil HCO3_cotransp PF00955.21 KER21997.1 - 1.2e-66 225.6 5.4 2.5e-66 224.6 5.4 1.4 1 1 0 1 1 1 1 HCO3- transporter family HCO3_cotransp PF00955.21 KER21998.1 - 3.5e-51 174.6 6.7 1.5e-42 146.2 2.3 2.1 2 0 0 2 2 2 2 HCO3- transporter family CrgA PF06781.12 KER21998.1 - 0.12 12.5 2.9 3.6 7.7 0.3 2.7 2 0 0 2 2 2 0 Cell division protein CrgA CHIP_TPR_N PF18391.1 KER22001.1 - 1.6e-14 54.4 0.0 1.2e-09 38.7 0.0 2.5 2 0 0 2 2 2 2 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 KER22001.1 - 1e-10 41.0 5.5 2.6e-06 27.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER22001.1 - 4.4e-09 35.8 6.9 0.002 18.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KER22001.1 - 2.2e-06 27.8 5.6 4.7e-06 26.7 5.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KER22001.1 - 3.8e-06 27.1 7.0 0.0093 16.2 1.9 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER22001.1 - 8.8e-05 22.1 3.5 0.12 12.0 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 KER22001.1 - 0.00016 21.5 2.9 0.092 12.8 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER22001.1 - 0.0041 17.7 0.2 0.095 13.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER22001.1 - 0.015 15.5 5.5 0.097 12.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3774 PF12609.8 KER22001.1 - 0.18 12.9 0.7 0.42 11.7 0.1 1.9 2 0 0 2 2 1 0 Wound-induced protein TPR_19 PF14559.6 KER22001.1 - 0.33 11.5 3.7 4.6 7.8 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat U-box PF04564.15 KER22002.1 - 5.2e-27 93.8 0.0 9.3e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KER22002.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein LCE6A PF15858.5 KER22002.1 - 0.11 13.3 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Late cornified envelope protein 6A family zf-RING_2 PF13639.6 KER22003.1 - 2.5e-09 37.3 13.3 7e-09 35.9 13.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER22003.1 - 4.4e-08 32.9 9.7 7.7e-08 32.1 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER22003.1 - 1.3e-07 31.3 12.7 2.8e-07 30.3 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER22003.1 - 1.6e-06 27.8 13.0 3.9e-06 26.6 13.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER22003.1 - 9.4e-06 25.8 7.1 9.4e-06 25.8 7.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KER22003.1 - 0.003 17.4 11.7 0.003 17.4 11.7 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KER22003.1 - 0.0031 17.2 6.8 0.0031 17.2 6.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KER22003.1 - 0.013 15.4 10.3 0.026 14.5 10.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER22003.1 - 0.016 15.3 11.9 0.052 13.6 11.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KER22003.1 - 2.9 8.1 13.6 6.4 7.0 13.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UAA PF08449.11 KER22004.1 - 4.5e-68 229.7 27.0 5.5e-68 229.4 27.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KER22004.1 - 0.21 11.7 36.3 0.035 14.3 11.3 3.0 2 1 1 3 3 3 0 EamA-like transporter family CxC6 PF18721.1 KER22005.1 - 0.96 9.8 3.7 4.5 7.6 0.3 2.4 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases DUF3074 PF11274.8 KER22006.1 - 0.01 15.8 0.3 0.012 15.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) WbqC PF08889.11 KER22006.1 - 0.059 13.3 0.2 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 WbqC-like protein family DUF2605 PF10792.9 KER22006.1 - 0.084 12.8 1.5 0.11 12.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Biotin_lipoyl PF00364.22 KER22008.1 - 2.6e-12 46.4 0.0 3.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KER22008.1 - 0.0099 16.2 0.2 0.015 15.7 0.2 1.3 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.23 KER22009.1 - 9e-54 182.4 0.5 7.2e-39 133.6 0.3 2.4 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) zf-MIZ PF02891.20 KER22010.1 - 2.5e-10 39.9 0.2 5.4e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ribosomal_S19e PF01090.19 KER22014.1 - 2.6e-32 111.4 0.0 4.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19e DUF4179 PF13786.6 KER22014.1 - 0.38 11.3 2.3 0.85 10.1 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Tic110 PF16940.5 KER22014.1 - 2.2 6.7 8.1 3.1 6.2 8.1 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter DEAD PF00270.29 KER22015.1 - 6.5e-46 156.3 0.0 3e-45 154.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER22015.1 - 6.4e-27 94.1 0.0 1.9e-26 92.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER22015.1 - 0.00072 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 KER22017.1 - 1e-50 168.6 4.9 6e-09 36.4 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Katanin_con80 PF13925.6 KER22017.1 - 4.2e-45 153.7 1.1 7.7e-45 152.8 0.9 1.5 2 0 0 2 2 2 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 KER22017.1 - 3.5e-17 62.5 0.1 0.0004 20.6 0.0 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER22017.1 - 2.4e-07 30.8 0.0 0.0032 17.4 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KER22017.1 - 0.00018 20.6 0.3 0.23 10.4 0.0 4.5 2 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KER22017.1 - 0.033 12.7 0.0 0.23 9.9 0.0 2.2 1 1 2 3 3 3 0 Cytochrome D1 heme domain EFG_II PF14492.6 KER22019.1 - 0.0017 18.4 3.9 0.32 11.1 0.4 2.6 1 1 1 2 2 2 2 Elongation Factor G, domain II DUF4973 PF16343.5 KER22019.1 - 0.56 10.3 2.5 20 5.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4973) Exo_endo_phos PF03372.23 KER22021.1 - 8.9e-05 22.1 0.1 0.00011 21.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KER22023.1 - 1.3e-71 234.7 17.2 8.6e-10 39.1 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22023.1 - 2.3e-24 85.5 0.5 0.00049 20.3 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER22023.1 - 9.1e-11 41.1 10.9 0.16 10.6 0.0 6.5 2 2 5 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KER22023.1 - 2.1e-09 36.6 0.1 0.02 13.6 0.0 4.3 1 1 4 5 5 5 3 Nup133 N terminal like Ge1_WD40 PF16529.5 KER22023.1 - 0.0018 17.3 7.5 0.23 10.4 0.8 4.0 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein RhlB PF12300.8 KER22023.1 - 0.0064 16.6 0.5 0.0064 16.6 0.5 2.0 2 0 0 2 2 2 1 ATP-dependent RNA helicase RhlB Cul7 PF11515.8 KER22024.1 - 0.026 14.8 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Thiolase_N PF00108.23 KER22026.1 - 6.5e-73 245.3 0.0 9.8e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KER22026.1 - 1.5e-42 144.1 0.1 3e-42 143.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain DnaJ PF00226.31 KER22027.1 - 9e-33 112.2 7.9 5.3e-16 58.5 0.0 3.4 4 0 0 4 4 4 2 DnaJ domain Homeodomain PF00046.29 KER22027.1 - 1.6e-20 72.7 5.2 3.9e-20 71.4 5.2 1.7 1 0 0 1 1 1 1 Homeodomain Histone PF00125.24 KER22027.1 - 2.8e-05 24.5 0.2 0.00011 22.6 0.2 2.1 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SOTI PF17079.5 KER22027.1 - 0.00041 20.7 0.2 3.1 8.3 0.0 3.6 3 0 0 3 3 3 2 Male-specific protein scotti Homeobox_KN PF05920.11 KER22027.1 - 0.0067 16.3 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain CBFD_NFYB_HMF PF00808.23 KER22027.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2280 PF10045.9 KER22027.1 - 0.016 15.5 0.3 9.4 6.6 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) HTH_23 PF13384.6 KER22027.1 - 0.028 14.2 0.1 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain eRF1_2 PF03464.15 KER22027.1 - 0.12 12.7 0.0 5.1 7.4 0.0 2.4 1 1 1 2 2 2 0 eRF1 domain 2 CPSase_L_D3 PF02787.19 KER22027.1 - 0.22 11.9 0.5 0.44 10.9 0.5 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LicD PF04991.13 KER22030.1 - 2.6e-11 44.1 1.5 1.4e-09 38.5 2.3 2.1 1 1 0 2 2 2 2 LicD family Topoisom_bac PF01131.20 KER22031.1 - 5.4e-75 253.0 0.0 6.8e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KER22031.1 - 4.5e-17 62.2 0.0 8.1e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-Sec23_Sec24 PF04810.15 KER22031.1 - 1.9 8.6 9.5 3.9 7.6 3.1 3.0 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Zn_Tnp_IS91 PF14319.6 KER22031.1 - 2.4 8.3 6.0 12 6.1 0.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain GCP_C_terminal PF04130.13 KER22033.1 - 7.7e-42 143.8 3.8 7.7e-42 143.8 3.8 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KER22033.1 - 1.3e-08 34.9 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal RAI16-like PF10257.9 KER22033.1 - 0.027 13.3 0.2 3.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Retinoic acid induced 16-like protein PRELI PF04707.14 KER22033.1 - 0.11 12.3 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 PRELI-like family Chromo_2 PF18704.1 KER22041.1 - 9.5e-20 70.6 0.3 1.9e-19 69.7 0.3 1.5 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 XPG_I PF00867.18 KER22041.1 - 4.9e-06 26.8 0.1 0.00016 21.9 0.1 2.5 1 1 1 2 2 2 1 XPG I-region XPG_N PF00752.17 KER22041.1 - 0.00042 20.7 0.0 0.00085 19.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Orai-1 PF07856.12 KER22042.1 - 2.8e-46 157.4 13.0 4.3e-46 156.7 13.0 1.3 1 0 0 1 1 1 1 Mediator of CRAC channel activity Pyr_redox_2 PF07992.14 KER22042.1 - 2e-22 79.8 0.0 6.6e-11 42.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KER22042.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain 7tm_1 PF00001.21 KER22042.1 - 0.0024 17.2 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAD_binding_2 PF00890.24 KER22042.1 - 0.0042 16.2 1.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KER22042.1 - 0.029 14.9 0.4 2.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KER22042.1 - 0.052 13.8 0.5 0.13 12.5 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KER22042.1 - 0.077 13.0 0.1 5.3 7.0 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Phage_holin_3_6 PF07332.11 KER22042.1 - 1.7 8.7 13.4 0.89 9.6 5.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Sugar_tr PF00083.24 KER22043.1 - 2.3e-26 92.7 21.2 3.3e-26 92.1 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER22043.1 - 4.1e-20 72.0 29.4 4.1e-20 72.0 29.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KER22044.1 - 5.9e-72 242.2 0.0 9e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22044.1 - 3.6e-31 108.4 0.0 5.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER22044.1 - 1.1e-06 27.9 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER22044.1 - 0.0025 17.2 0.0 0.0069 15.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Prefoldin PF02996.17 KER22045.1 - 0.062 13.2 0.1 0.062 13.2 0.1 5.3 5 1 2 7 7 7 0 Prefoldin subunit Filament PF00038.21 KER22045.1 - 0.21 11.1 52.3 0.39 10.3 22.8 3.6 2 1 1 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 KER22045.1 - 0.43 11.0 16.5 5.8 7.4 0.8 5.7 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) SPT2 PF08243.11 KER22046.1 - 2.5e-14 53.8 14.4 2.5e-14 53.8 14.4 1.8 2 0 0 2 2 2 1 SPT2 chromatin protein HUN PF08729.10 KER22046.1 - 0.007 16.3 7.3 0.015 15.3 7.3 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Kelch_1 PF01344.25 KER22047.1 - 4.8e-66 218.1 7.1 1.3e-14 53.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KER22047.1 - 5.6e-38 128.0 6.1 8.7e-08 32.2 0.0 7.0 3 2 4 7 7 7 6 Kelch motif BACK PF07707.15 KER22047.1 - 3.2e-23 81.8 2.7 4.2e-19 68.5 0.7 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch BTB PF00651.31 KER22047.1 - 1.3e-22 80.2 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KER22047.1 - 2.9e-19 68.2 5.4 0.0022 17.9 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KER22047.1 - 7.6e-18 64.3 6.6 0.00074 19.7 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KER22047.1 - 1.5e-12 47.3 3.1 0.026 14.5 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KER22047.1 - 5e-08 32.7 5.4 0.31 11.1 0.0 5.3 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.8 KER22047.1 - 0.00013 22.1 0.1 0.035 14.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) PQQ_3 PF13570.6 KER22047.1 - 0.011 16.2 5.4 24 5.6 0.1 5.1 5 0 0 5 5 5 0 PQQ-like domain WD40 PF00400.32 KER22048.1 - 1.4e-21 76.4 12.9 4.2e-05 24.2 0.1 8.6 7 1 0 7 7 7 5 WD domain, G-beta repeat EF-hand_8 PF13833.6 KER22048.1 - 9.5e-05 22.2 0.2 0.00022 21.0 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Nucleoporin_N PF08801.11 KER22048.1 - 0.0002 20.3 0.9 0.031 13.0 0.1 2.4 1 1 1 2 2 2 2 Nup133 N terminal like EF-hand_7 PF13499.6 KER22048.1 - 0.0077 16.7 0.1 0.022 15.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER22048.1 - 0.038 13.9 1.3 0.12 12.3 1.3 1.9 1 0 0 1 1 1 0 EF-hand domain ANAPC4_WD40 PF12894.7 KER22048.1 - 0.055 13.8 0.1 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 KER22048.1 - 0.17 11.5 0.9 0.46 10.2 0.9 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KER22048.1 - 1 9.0 3.1 2.4 7.8 3.1 1.6 1 0 0 1 1 1 0 EF hand SpoU_methylase PF00588.19 KER22049.1 - 1.4e-22 80.4 0.0 3.5e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KER22049.1 - 2.4e-08 34.2 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SKI PF01202.22 KER22050.1 - 2.8e-15 56.8 0.0 3.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KER22050.1 - 6.4e-10 39.4 0.0 8.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KER22050.1 - 2e-09 38.1 0.0 3.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 KER22050.1 - 1.4e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain Cytidylate_kin PF02224.18 KER22050.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 KER22050.1 - 0.00018 22.0 0.1 0.00025 21.5 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KER22050.1 - 0.00019 21.6 0.0 0.00026 21.2 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.6 KER22050.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KER22050.1 - 0.0019 18.1 0.0 0.012 15.5 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain CoaE PF01121.20 KER22050.1 - 0.0023 17.7 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 KER22050.1 - 0.0035 17.8 0.0 0.013 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KER22050.1 - 0.0078 16.1 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 Deoxynucleoside kinase APS_kinase PF01583.20 KER22050.1 - 0.019 14.8 0.0 0.02 14.8 0.0 1.3 1 1 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KER22050.1 - 0.029 14.9 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KER22050.1 - 0.032 14.5 0.1 0.096 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KER22050.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KER22050.1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KER22050.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 KER22050.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase PRK PF00485.18 KER22050.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Kinesin PF00225.23 KER22051.1 - 4.1e-119 397.4 0.4 7e-119 396.6 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER22051.1 - 3.8e-25 88.6 0.0 1.1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding MULE PF10551.9 KER22051.1 - 9.6e-20 70.8 0.1 2.3e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain PIF1 PF05970.14 KER22051.1 - 0.015 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 KER22051.1 - 0.041 13.6 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain FAR1 PF03101.15 KER22051.1 - 0.18 12.5 2.3 0.32 11.7 0.1 2.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain Complex1_LYR PF05347.15 KER22053.1 - 1.6e-07 31.2 2.1 1.5e-06 28.1 2.1 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KER22053.1 - 0.0043 17.8 0.2 0.0061 17.3 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Tropomyosin PF00261.20 KER22055.1 - 2.5e-07 30.3 44.1 7.7e-07 28.7 44.0 1.7 1 1 0 1 1 1 1 Tropomyosin Spc7 PF08317.11 KER22055.1 - 1.9e-05 23.7 37.5 0.002 17.1 5.9 2.8 2 1 1 3 3 3 2 Spc7 kinetochore protein DUF1664 PF07889.12 KER22055.1 - 0.0025 17.9 2.3 0.0025 17.9 2.3 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Cep57_CLD PF14073.6 KER22055.1 - 0.005 16.9 39.0 0.04 13.9 22.5 2.1 2 0 0 2 2 2 2 Centrosome localisation domain of Cep57 Fib_alpha PF08702.10 KER22055.1 - 0.0059 16.8 22.8 0.19 11.9 4.1 3.2 2 1 1 3 3 3 3 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KER22055.1 - 0.026 14.7 45.7 0.064 13.4 19.8 3.6 1 1 2 4 4 4 0 Tropomyosin like HOOK PF05622.12 KER22055.1 - 0.027 12.7 34.3 0.17 10.0 19.6 2.2 2 0 0 2 2 2 0 HOOK protein Snapin_Pallidin PF14712.6 KER22055.1 - 0.027 14.9 4.3 0.027 14.9 4.3 4.4 2 2 1 3 3 3 0 Snapin/Pallidin DUF2353 PF09789.9 KER22055.1 - 0.029 13.8 30.5 0.051 12.9 18.7 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 KER22055.1 - 0.045 14.0 40.6 0.51 10.5 25.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KER22055.1 - 0.045 13.6 32.1 0.2 11.5 11.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 KER22055.1 - 0.056 12.1 24.9 0.22 10.1 14.5 2.0 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 KER22055.1 - 0.13 12.7 33.5 0.074 13.5 20.0 2.3 1 1 1 2 2 2 0 Fez1 Pox_F11 PF04943.12 KER22055.1 - 0.13 11.3 8.6 0.16 11.0 8.6 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Atg14 PF10186.9 KER22055.1 - 0.26 10.3 28.0 0.55 9.3 8.7 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 KER22055.1 - 0.4 11.4 21.2 0.85 10.4 1.1 3.7 2 2 1 3 3 3 0 Occludin homology domain BLOC1_2 PF10046.9 KER22055.1 - 0.4 11.0 30.1 1 9.7 6.6 4.5 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.11 KER22055.1 - 0.44 9.9 32.6 1.2 8.4 4.8 2.3 2 1 0 2 2 2 0 Rabaptin-like protein CALCOCO1 PF07888.11 KER22055.1 - 0.48 9.2 39.6 0.88 8.4 39.6 1.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DS PF01916.17 KER22055.1 - 0.67 9.1 4.2 0.3 10.3 1.5 1.7 1 1 1 2 2 2 0 Deoxyhypusine synthase DUF4201 PF13870.6 KER22055.1 - 0.7 9.6 35.0 0.21 11.3 14.9 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) DUF489 PF04356.12 KER22055.1 - 3.1 7.8 14.9 2 8.4 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF489) DUF4743 PF15916.5 KER22055.1 - 3.7 7.5 7.6 1.5 8.8 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4743) CENP-H PF05837.12 KER22055.1 - 3.7 8.0 39.9 0.7 10.3 9.5 3.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Peripla_BP_2 PF01497.18 KER22055.1 - 4.6 6.7 14.8 2.8 7.4 3.1 3.1 2 1 1 3 3 3 0 Periplasmic binding protein Sec34 PF04136.15 KER22055.1 - 6.2 6.7 25.2 2.7 7.9 2.1 3.3 2 2 0 3 3 3 0 Sec34-like family Fmp27_SW PF10305.9 KER22055.1 - 6.4 7.5 6.7 25 5.7 0.2 3.1 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain MAD PF05557.13 KER22055.1 - 6.5 5.0 39.2 0.28 9.5 22.3 2.1 1 1 0 2 2 2 0 Mitotic checkpoint protein DUF2400 PF09674.10 KER22055.1 - 8.3 6.3 9.7 14 5.6 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) HrpB7 PF09486.10 KER22055.1 - 8.4 6.8 34.8 6.1 7.2 0.9 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ERM PF00769.19 KER22055.1 - 8.9 6.0 47.1 2 8.2 13.0 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family EzrA PF06160.12 KER22055.1 - 9.7 4.2 32.6 2.8 6.0 6.4 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA RabGAP-TBC PF00566.18 KER22057.1 - 1.1e-46 159.2 1.6 1.5e-46 158.8 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain dNK PF01712.19 KER22059.1 - 2.3e-36 125.6 0.0 2.7e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 KER22059.1 - 0.0037 17.4 0.0 0.0087 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KER22059.1 - 0.063 13.8 0.0 0.086 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KER22059.1 - 0.068 13.6 0.0 0.096 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KER22059.1 - 0.24 11.0 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase LRR_9 PF14580.6 KER22061.1 - 0.052 13.1 1.2 0.088 12.3 1.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 KER22061.1 - 0.073 12.8 3.7 0.49 10.2 1.0 2.5 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KER22061.1 - 0.12 12.8 4.5 2.8 8.5 0.7 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Histone PF00125.24 KER22062.1 - 2.2e-18 66.8 0.0 2.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KER22062.1 - 6.3e-12 45.0 0.6 1.1e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KER22062.1 - 0.021 15.1 0.1 0.062 13.6 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ubiquitin PF00240.23 KER22063.1 - 1.5e-12 47.1 0.0 2.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 KER22063.1 - 4.6e-06 26.7 12.8 8.4e-06 25.8 12.8 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KER22063.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KER22063.1 - 0.04 13.9 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MFS_1 PF07690.16 KER22066.1 - 2e-35 122.4 36.3 6.4e-19 68.1 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KER22066.1 - 0.064 11.5 15.1 0.052 11.8 10.9 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LapA_dom PF06305.11 KER22066.1 - 3.5 7.5 0.0 3.5 7.5 0.0 4.3 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KER22068.1 - 1.3e-69 234.5 0.0 1.7e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22068.1 - 5.4e-33 114.4 0.0 7.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER22068.1 - 7.3e-08 32.1 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER22068.1 - 0.035 13.1 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Herpes_glycoH_C PF17488.2 KER22069.1 - 0.016 15.0 0.3 1.8 8.4 0.2 2.2 1 1 1 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain RVT_1 PF00078.27 KER22070.1 - 5.4e-17 62.0 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_3 PF13927.6 KER22070.1 - 0.057 14.0 0.1 0.71 10.5 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Peptidase_C13 PF01650.18 KER22073.1 - 4.9e-29 101.6 3.4 7.1e-20 71.6 0.9 2.0 2 0 0 2 2 2 2 Peptidase C13 family Omp28 PF11551.8 KER22073.1 - 0.081 12.8 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein Omp28 Peptidase_C13 PF01650.18 KER22074.1 - 0.0028 17.2 0.1 0.0037 16.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family E1_DerP2_DerF2 PF02221.15 KER22075.1 - 4e-05 24.1 0.0 4.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF1918 PF08940.11 KER22075.1 - 0.043 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) zf-UBR PF02207.20 KER22076.1 - 1.1e-11 44.7 8.1 1.1e-11 44.7 8.1 3.1 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 KER22076.1 - 1.9e-06 27.6 4.2 1.9e-06 27.6 4.2 3.0 3 1 0 3 3 3 1 PHD-finger TetR_C_7 PF14246.6 KER22076.1 - 0.034 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain zf-H2C2_2 PF13465.6 KER22077.1 - 1.6e-42 142.1 52.7 4.4e-10 39.5 0.4 9.3 8 1 1 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.26 KER22077.1 - 3e-35 118.7 64.7 8.4e-06 26.0 0.7 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22077.1 - 3.6e-29 98.9 61.1 0.004 17.9 0.7 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER22077.1 - 4.8e-16 58.6 37.8 0.00021 21.5 0.3 9.1 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER22077.1 - 9.1e-15 54.5 50.8 0.00061 20.1 1.0 8.9 9 0 0 9 9 9 7 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER22077.1 - 4.6e-10 39.2 55.6 0.00045 20.1 0.2 8.3 9 0 0 9 9 9 5 C2H2-type zinc finger BolA PF01722.18 KER22077.1 - 0.0027 18.0 7.8 9.7 6.6 0.4 5.7 3 1 2 5 5 5 1 BolA-like protein zinc_ribbon_15 PF17032.5 KER22077.1 - 0.0031 18.2 31.7 0.023 15.4 1.3 4.7 1 1 3 4 4 4 2 zinc-ribbon family zf-RING_5 PF14634.6 KER22077.1 - 0.0069 16.3 7.1 0.0069 16.3 7.1 6.2 2 2 3 6 6 4 1 zinc-RING finger domain zf_C2H2_ZHX PF18387.1 KER22077.1 - 0.015 14.9 2.6 0.015 14.9 2.6 5.4 3 2 3 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain PHF5 PF03660.14 KER22077.1 - 0.052 13.8 0.7 0.052 13.8 0.7 3.8 1 1 3 4 4 4 0 PHF5-like protein Zn-C2H2_12 PF18112.1 KER22077.1 - 0.18 12.3 0.2 0.18 12.3 0.2 6.3 7 0 0 7 7 7 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 KER22077.1 - 1.6 9.4 30.6 1e+02 3.6 0.2 6.6 2 1 3 5 5 3 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KER22077.1 - 6.1 6.7 20.2 15 5.5 1.8 5.5 3 3 4 7 7 7 0 GAGA factor Ribosomal_S27e PF01667.17 KER22077.1 - 6.2 6.6 17.3 18 5.1 0.1 5.7 7 0 0 7 7 6 0 Ribosomal protein S27 zf-C2H2_2 PF12756.7 KER22077.1 - 8.2 6.8 41.0 13 6.2 2.3 8.1 1 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) Sec10 PF07393.11 KER22079.1 - 4.8e-97 326.1 12.0 2.6e-93 313.8 12.0 3.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 SlyX PF04102.12 KER22079.1 - 0.022 15.4 0.9 0.19 12.3 0.9 2.7 1 0 0 1 1 1 0 SlyX Occludin_ELL PF07303.13 KER22079.1 - 0.26 12.0 2.7 2.9 8.7 0.0 3.4 2 1 1 3 3 3 0 Occludin homology domain Spc24 PF08286.11 KER22079.1 - 0.3 11.3 1.2 2.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 MRP-L27 PF09809.9 KER22080.1 - 2.2e-11 43.6 0.1 3.2e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pro_3_hydrox_C PF05373.11 KER22080.1 - 0.096 12.8 0.3 0.48 10.5 0.1 2.1 2 1 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal DUF2353 PF09789.9 KER22081.1 - 2.6e-48 165.0 12.0 3.4e-48 164.6 12.0 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) MscS_porin PF12795.7 KER22081.1 - 0.0022 17.6 2.1 0.0022 17.6 2.1 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain HMMR_C PF15908.5 KER22081.1 - 0.038 14.3 5.9 0.77 10.0 0.2 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal SOGA PF11365.8 KER22081.1 - 0.071 14.2 8.7 3 9.0 0.1 2.7 2 1 0 2 2 2 0 Protein SOGA COG2 PF06148.11 KER22081.1 - 0.36 10.9 3.1 0.35 11.0 1.3 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Mac PF12464.8 KER22081.1 - 0.86 9.9 3.7 3.8 7.8 3.6 2.3 1 1 0 1 1 1 0 Maltose acetyltransferase FAM184 PF15665.5 KER22081.1 - 1.3 8.7 11.7 5.5 6.7 1.2 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 KER22081.1 - 1.6 8.8 15.7 0.43 10.6 8.8 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 KER22081.1 - 1.6 8.7 7.9 0.31 10.9 2.7 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat EBV-NA1 PF02905.14 KER22082.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Pkinase_Tyr PF07714.17 KER22083.1 - 2e-87 292.7 0.0 4.7e-87 291.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KER22083.1 - 4.5e-37 127.8 0.0 2.1e-35 122.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Ig_3 PF13927.6 KER22083.1 - 8.2e-06 26.3 0.4 1.9 9.2 0.0 4.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KER22083.1 - 6.6e-05 23.0 1.3 0.053 13.7 0.0 4.4 4 1 0 4 4 4 1 Immunoglobulin V-set domain Kinase-like PF14531.6 KER22083.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ig PF00047.25 KER22083.1 - 0.015 15.5 2.8 3.6 7.8 0.3 3.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER22083.1 - 0.037 14.1 0.0 10 6.3 0.0 2.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain SH3_1 PF00018.28 KER22086.1 - 4.6e-05 22.9 0.0 8.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER22086.1 - 4.7e-05 23.2 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KER22086.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RVT_1 PF00078.27 KER22087.1 - 2e-07 30.8 0.0 3e-07 30.2 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.22 KER22088.1 - 1e-07 31.7 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctf8 PF09696.10 KER22088.1 - 0.066 13.6 3.7 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Ctf8 BCL9 PF11502.8 KER22088.1 - 0.12 12.2 2.0 11 6.0 0.5 2.5 2 0 0 2 2 2 0 B-cell lymphoma 9 protein TMEM223 PF14640.6 KER22090.1 - 6.1e-13 49.3 0.0 3.4e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 Transmembrane protein 223 Proteasome PF00227.26 KER22091.1 - 4.2e-29 101.4 0.0 4.9e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SH2 PF00017.24 KER22093.1 - 1.8e-16 60.0 0.0 3.8e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain FOG_N PF15888.5 KER22093.1 - 0.11 12.8 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 Folded gastrulation N-terminus Uma2 PF05685.12 KER22095.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.0 1 0 0 1 1 1 0 Putative restriction endonuclease Calpain_III PF01067.22 KER22096.1 - 1.2e-17 64.5 0.0 5.2e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III C2 PF00168.30 KER22096.1 - 4.4e-12 46.2 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Peptidase_C2 PF00648.21 KER22096.1 - 8.2e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Calpain family cysteine protease GATA PF00320.27 KER22098.1 - 7.9e-27 92.6 24.0 5.8e-15 54.6 4.9 3.0 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KER22098.1 - 0.00016 21.1 9.8 0.02 14.4 0.6 2.9 3 0 0 3 3 3 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KER22098.1 - 0.073 13.2 1.4 13 6.0 0.1 2.9 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 KER22098.1 - 0.11 12.6 3.0 1.1 9.4 0.4 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like NMD3 PF04981.13 KER22098.1 - 0.3 10.5 3.2 20 4.5 2.4 2.5 2 1 0 2 2 2 0 NMD3 family Auto_anti-p27 PF06677.12 KER22098.1 - 0.91 9.7 10.0 1 9.6 0.4 2.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Vps36-NZF-N PF16988.5 KER22098.1 - 1.7 8.1 5.9 1.4 8.4 0.2 3.2 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain eIF-5_eIF-2B PF01873.17 KER22098.1 - 4.8 7.1 6.0 7.8 6.4 1.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 LRR_8 PF13855.6 KER22099.1 - 2.6e-14 52.7 29.1 8.8e-07 28.6 2.0 6.4 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KER22099.1 - 1.2e-13 51.0 37.7 8.1e-05 22.9 0.6 7.1 4 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER22099.1 - 0.0021 17.6 8.5 0.89 9.0 0.6 3.7 1 1 3 4 4 4 4 Leucine-rich repeat DUF4407 PF14362.6 KER22099.1 - 1.8 7.9 4.5 3.2 7.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_1 PF00515.28 KER22100.1 - 1.5e-45 151.2 23.9 4.1e-07 29.6 0.0 14.5 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 KER22100.1 - 1.7e-36 121.3 19.9 0.0002 21.3 0.0 13.8 13 1 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KER22100.1 - 1.9e-36 121.2 26.6 5.1e-05 23.1 0.0 15.6 16 1 0 16 16 15 7 Tetratricopeptide repeat TPR_19 PF14559.6 KER22100.1 - 6.1e-35 119.6 16.8 1.8e-07 31.5 0.2 10.7 8 1 2 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 KER22100.1 - 3.6e-25 86.5 16.5 0.014 16.2 0.0 13.4 11 4 4 15 15 15 6 Tetratricopeptide repeat TPR_16 PF13432.6 KER22100.1 - 7.9e-23 80.8 9.2 6.1e-05 23.6 0.1 10.3 8 2 2 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KER22100.1 - 2.2e-22 77.8 21.3 0.012 15.9 0.0 14.1 15 1 0 15 15 13 5 Tetratricopeptide repeat TPR_12 PF13424.6 KER22100.1 - 3.4e-21 75.3 34.2 0.00038 20.7 0.3 10.8 9 3 2 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KER22100.1 - 1.2e-17 63.3 9.9 0.008 15.8 0.0 10.1 10 2 1 11 11 11 4 TPR repeat TPR_6 PF13174.6 KER22100.1 - 1.5e-16 59.8 20.6 0.02 15.5 0.0 11.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 KER22100.1 - 5.3e-14 51.1 20.7 0.27 11.3 0.0 12.3 13 1 0 13 13 13 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KER22100.1 - 7.3e-09 35.7 15.0 0.0038 17.4 1.4 6.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KER22100.1 - 1e-06 28.8 2.3 0.059 13.5 0.0 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KER22100.1 - 0.00037 20.8 0.0 7.6 7.5 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER22100.1 - 0.0011 18.8 32.6 0.035 14.0 0.1 10.3 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_3 PF07720.12 KER22100.1 - 0.0044 17.0 18.9 0.26 11.3 3.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 KER22100.1 - 0.0062 16.3 0.1 0.0062 16.3 0.1 4.3 4 2 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Rapsyn_N PF10579.9 KER22100.1 - 0.01 15.9 1.9 3.8 7.7 0.3 4.1 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region BolA PF01722.18 KER22101.1 - 2.7e-23 82.0 0.1 3.5e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein Xol-1_GHMP-like PF09109.10 KER22101.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF1330 PF07045.11 KER22102.1 - 1.8e-07 31.4 0.0 0.00053 20.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) Galactosyl_T PF01762.21 KER22104.1 - 1.7e-08 34.5 0.1 1.2e-05 25.3 0.1 2.3 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER22104.1 - 4.8e-05 22.9 0.2 0.00076 19.0 0.2 2.1 1 1 0 1 1 1 1 Fringe-like THDPS_M PF14789.6 KER22104.1 - 0.18 11.9 0.0 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle AKAP7_NLS PF10469.9 KER22105.1 - 1.2e-41 143.0 0.0 7.1e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KER22105.1 - 1.2e-13 51.2 0.7 2.1e-06 27.7 0.3 2.3 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KER22105.1 - 3.8e-07 30.2 0.1 1.3 9.3 0.0 4.5 3 1 1 4 4 4 3 LigT like Phosphoesterase MJ1316 PF04457.12 KER22105.1 - 2.4e-06 28.2 0.0 9.8e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain Pkinase PF00069.25 KER22106.1 - 5.2e-56 189.9 0.0 1.9e-55 188.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22106.1 - 5.6e-36 124.2 0.0 1.6e-35 122.7 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 KER22106.1 - 0.00054 20.1 18.5 0.00054 20.1 18.5 4.5 3 2 1 4 4 4 1 Polo kinase kinase ABC1 PF03109.16 KER22106.1 - 0.77 9.9 7.8 1.7 8.8 0.0 3.5 3 0 0 3 3 3 0 ABC1 family RVT_1 PF00078.27 KER22108.1 - 2.9e-37 128.3 0.0 5.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.26 KER22109.1 - 3.3e-29 101.7 0.0 3.5e-28 98.4 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit ING PF12998.7 KER22110.1 - 6.3e-13 49.2 0.6 6.3e-13 49.2 0.6 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KER22110.1 - 8.1e-06 25.6 7.0 8.1e-06 25.6 7.0 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 KER22110.1 - 0.013 15.8 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Sec5 PF15469.6 KER22110.1 - 0.018 14.8 1.5 0.03 14.1 1.0 1.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 zf-H2C2_2 PF13465.6 KER22111.1 - 8.9e-10 38.6 20.4 1.8e-05 24.9 3.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER22111.1 - 4.5e-09 36.3 27.9 0.00023 21.5 1.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type RT_RNaseH PF17917.1 KER22111.1 - 4.9e-07 30.0 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C2H2_4 PF13894.6 KER22111.1 - 0.00028 21.5 29.8 0.0081 16.9 1.3 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KER22111.1 - 0.0017 18.1 2.4 0.0017 18.1 2.4 3.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain RT_RNaseH_2 PF17919.1 KER22111.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-C2HC_2 PF13913.6 KER22111.1 - 0.02 14.8 2.4 0.023 14.6 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 KER22111.1 - 0.21 12.1 3.0 2.6 8.6 0.1 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KER22111.1 - 0.41 10.7 10.0 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER22111.1 - 0.42 11.0 6.4 0.92 9.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KER22113.1 - 2.8e-17 62.1 59.0 2.7e-05 24.4 1.3 9.8 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22113.1 - 4.1e-10 39.6 66.2 0.01 16.6 5.5 10.4 10 1 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER22113.1 - 1.3e-05 25.4 3.2 0.0024 18.2 0.2 9.0 10 1 0 10 10 10 3 Zinc-finger double domain Ribosomal_L7Ae PF01248.26 KER22113.1 - 1.4e-05 24.7 0.0 4e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FOXP-CC PF16159.5 KER22113.1 - 0.0056 17.3 0.3 0.0056 17.3 0.3 3.4 3 0 0 3 3 3 1 FOXP coiled-coil domain DUF2795 PF11387.8 KER22113.1 - 0.14 12.4 0.1 16 5.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) FUSC PF04632.12 KER22113.1 - 0.46 9.0 1.3 0.92 8.0 1.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-RING_7 PF02591.15 KER22113.1 - 0.61 10.3 0.0 0.61 10.3 0.0 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_jaz PF12171.8 KER22113.1 - 3.4 8.1 30.0 0.56 10.6 0.4 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-ribbon_3 PF13248.6 KER22113.1 - 8.3 6.0 12.6 2.1 7.8 0.2 4.5 4 0 0 4 4 4 0 zinc-ribbon domain ABC_tran PF00005.27 KER22117.1 - 4.1e-43 147.2 0.1 3.6e-23 82.6 0.0 4.3 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KER22117.1 - 3.4e-19 68.7 2.4 3.4e-19 68.7 2.4 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KER22117.1 - 8.4e-17 61.9 10.6 5.4e-05 23.1 0.1 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER22117.1 - 1.8e-08 34.1 0.2 0.23 10.9 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KER22117.1 - 6.2e-08 32.3 0.0 0.007 16.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KER22117.1 - 2.4e-07 30.8 0.0 0.0089 15.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 KER22117.1 - 2.5e-07 31.2 0.0 0.0014 19.1 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KER22117.1 - 5.1e-07 30.4 3.4 0.0093 16.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KER22117.1 - 1.4e-06 28.6 0.3 0.009 16.3 0.0 3.4 4 1 0 4 4 2 2 AAA domain AAA_14 PF13173.6 KER22117.1 - 2.2e-06 27.7 0.0 0.028 14.4 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KER22117.1 - 2.8e-06 27.8 0.0 0.038 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KER22117.1 - 1.7e-05 24.8 0.0 0.082 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KER22117.1 - 1.7e-05 25.1 0.0 0.27 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KER22117.1 - 2e-05 24.8 0.0 0.3 11.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KER22117.1 - 0.00011 22.7 0.1 0.3 11.6 0.0 3.7 4 1 0 4 4 4 1 AAA domain Rad17 PF03215.15 KER22117.1 - 0.00014 21.9 0.0 0.89 9.5 0.0 2.8 2 0 0 2 2 2 2 Rad17 P-loop domain NACHT PF05729.12 KER22117.1 - 0.0002 21.3 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 KER22117.1 - 0.00026 20.8 0.0 0.36 10.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KER22117.1 - 0.00026 21.3 0.0 0.53 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KER22117.1 - 0.00053 20.0 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KER22117.1 - 0.00056 19.2 0.0 0.3 10.2 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain MMR_HSR1 PF01926.23 KER22117.1 - 0.00059 19.9 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KER22117.1 - 0.00066 19.8 0.0 0.28 11.2 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_5 PF07728.14 KER22117.1 - 0.00087 19.3 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KER22117.1 - 0.002 17.7 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KER22117.1 - 0.0022 17.7 0.0 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KER22117.1 - 0.0037 17.7 0.0 7.2 7.0 0.0 3.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KER22117.1 - 0.0039 16.8 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_27 PF13514.6 KER22117.1 - 0.0045 16.6 0.9 2.3 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KER22117.1 - 0.0093 15.5 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 KER22117.1 - 0.011 15.9 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KER22117.1 - 0.019 14.7 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 KER22117.1 - 0.021 14.5 0.2 1 9.0 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase Zeta_toxin PF06414.12 KER22117.1 - 0.027 13.7 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 KER22117.1 - 0.043 12.5 0.0 1.8 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KER22117.1 - 0.044 13.5 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 KER22117.1 - 0.061 12.3 0.1 13 4.6 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KER22117.1 - 0.064 13.0 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KER22117.1 - 0.072 12.2 0.0 1.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KER22117.1 - 0.085 12.4 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KER22117.1 - 0.088 12.8 0.0 2 8.4 0.0 2.6 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TPR_20 PF14561.6 KER22117.1 - 0.11 12.9 3.1 27 5.2 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat MukB PF04310.12 KER22117.1 - 0.19 11.5 1.6 6.1 6.6 0.0 3.2 4 0 0 4 4 3 0 MukB N-terminal DUF1151 PF06625.11 KER22117.1 - 3 7.8 7.6 0.22 11.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Sema PF01403.19 KER22120.1 - 1.1e-14 54.1 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Sema domain DUF473 PF04322.12 KER22120.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF473) GCN5L1 PF06320.13 KER22122.1 - 5.9e-28 97.3 2.1 6.6e-28 97.1 2.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Snapin_Pallidin PF14712.6 KER22122.1 - 0.011 16.1 1.6 0.018 15.5 1.5 1.5 1 1 0 1 1 1 0 Snapin/Pallidin Sec2p PF06428.11 KER22122.1 - 0.059 13.3 0.9 0.08 12.9 0.9 1.4 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p MogR_DNAbind PF12181.8 KER22122.1 - 0.068 13.1 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Bestrophin PF01062.21 KER22123.1 - 2.4e-46 158.4 0.4 3.9e-46 157.8 0.4 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TFIIF_beta_N PF17683.1 KER22123.1 - 1.8e-19 70.8 0.0 3.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KER22123.1 - 8.4e-07 29.0 0.1 1.4e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain BTB_2 PF02214.22 KER22125.1 - 2.6e-18 66.2 0.0 5.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KER22125.1 - 3.5e-05 24.0 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KER22125.1 - 0.0026 17.9 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain JHY PF15261.6 KER22128.1 - 0.19 12.4 0.2 0.19 12.4 0.2 2.5 2 1 0 2 2 2 0 Jhy protein CSRNP_N PF16019.5 KER22129.1 - 1.5e-44 152.5 10.9 8e-29 101.1 7.3 2.2 2 0 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus LRS4 PF10422.9 KER22129.1 - 4.9 6.7 6.9 0.48 9.9 1.9 1.8 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Ras PF00071.22 KER22130.1 - 3.3e-57 192.6 0.2 8.5e-57 191.3 0.2 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER22130.1 - 2.9e-32 111.4 0.1 1.2e-31 109.5 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER22130.1 - 3.6e-10 39.6 0.1 4.6e-09 36.0 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER22130.1 - 1.9e-05 24.7 0.0 5.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER22130.1 - 0.00062 19.3 0.0 0.0019 17.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KER22130.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KER22130.1 - 0.0032 17.4 0.2 0.027 14.4 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KER22130.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER22130.1 - 0.057 13.9 0.0 0.083 13.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KER22130.1 - 0.06 13.7 0.1 0.09 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KER22130.1 - 0.069 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_21 PF13304.6 KER22130.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1128 PF06569.11 KER22130.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) TniB PF05621.11 KER22130.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Cas9_REC PF16592.5 KER22130.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 AAA_24 PF13479.6 KER22130.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KER22130.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 KER22130.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 KER22130.1 - 0.18 11.7 0.0 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Tubulin PF00091.25 KER22131.1 - 3.2e-49 167.8 0.0 5.4e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER22131.1 - 1.4e-22 80.2 0.0 4.6e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER22131.1 - 0.00058 19.6 0.0 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 Tubulin domain HTH_IclR PF09339.10 KER22131.1 - 0.077 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Tubulin PF00091.25 KER22132.1 - 2e-54 184.8 0.0 2.9e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER22132.1 - 2.9e-28 98.6 0.0 6.4e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KER22132.1 - 0.0042 16.3 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Serglycin PF04360.12 KER22132.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Serglycin Tubulin_3 PF14881.6 KER22132.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DUF2574 PF10836.8 KER22133.1 - 0.013 15.4 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Cytochrom_C PF00034.21 KER22135.1 - 8.8e-13 49.2 0.1 1.2e-12 48.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KER22135.1 - 1.6e-07 31.5 1.9 9.5e-07 29.1 1.9 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KER22135.1 - 3.8e-05 23.4 0.2 0.00056 19.6 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain UPF0128 PF03673.13 KER22135.1 - 0.01 15.3 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Dehyd-heme_bind PF09098.10 KER22135.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Asp PF00026.23 KER22137.1 - 1.9e-31 109.7 0.0 4.4e-18 65.8 0.0 3.4 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER22137.1 - 5.4e-08 33.3 0.5 2.4e-05 24.7 0.3 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal UCH PF00443.29 KER22138.1 - 0.0018 17.8 0.0 0.0062 16.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER22138.1 - 0.22 11.1 1.4 0.45 10.0 1.5 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Adaptin_N PF01602.20 KER22140.1 - 9.1e-141 470.0 5.9 1.4e-140 469.3 5.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KER22140.1 - 9.8e-18 64.7 4.6 4e-16 59.5 0.4 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KER22140.1 - 1e-08 35.4 3.3 7.4e-05 23.1 0.3 4.6 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.22 KER22140.1 - 9.2e-08 31.7 0.7 0.33 11.3 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat AP3B1_C PF14796.6 KER22140.1 - 3.3e-07 30.7 0.0 4.2e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_EZ PF13513.6 KER22140.1 - 1.1 9.8 4.3 4.5 7.9 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat CD36 PF01130.21 KER22143.1 - 3.2e-103 345.8 0.0 4.3e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 CD36 family zf-RING_11 PF17123.5 KER22143.1 - 0.005 16.6 0.8 0.0095 15.7 0.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger Shisa PF13908.6 KER22143.1 - 0.066 13.5 1.5 0.16 12.2 1.5 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-RING_2 PF13639.6 KER22143.1 - 0.1 12.9 0.5 0.36 11.2 0.5 1.9 1 0 0 1 1 1 0 Ring finger domain DUF4703 PF15775.5 KER22144.1 - 0.023 14.5 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) HLH PF00010.26 KER22149.1 - 1.7e-06 27.9 1.5 3.2e-06 27.0 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 KER22150.1 - 5e-55 186.7 0.0 1e-54 185.7 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain CaMKII_AD PF08332.10 KER22150.1 - 2.6e-48 163.4 0.0 4.9e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 KER22150.1 - 2.9e-20 72.6 0.0 4.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.6 KER22150.1 - 2.2e-09 37.7 0.0 3.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KER22150.1 - 3.9e-08 33.6 0.0 6.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Pkinase_fungal PF17667.1 KER22150.1 - 0.002 17.0 0.0 0.0048 15.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase VPS28 PF03997.12 KER22153.1 - 6e-46 156.5 0.5 8.9e-46 156.0 0.5 1.2 1 0 0 1 1 1 1 VPS28 protein SAPS PF04499.15 KER22154.1 - 9.8e-12 44.4 0.0 7.3e-05 21.7 0.0 2.8 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein DUF366 PF04017.12 KER22156.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF366) GEN1_C PF18380.1 KER22156.1 - 0.076 13.9 0.0 0.12 13.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain GTP_EFTU PF00009.27 KER22157.1 - 1.1e-43 149.1 0.0 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KER22157.1 - 5e-33 114.3 5.7 8.7e-24 84.4 0.0 2.4 2 0 0 2 2 2 2 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 KER22157.1 - 2e-22 79.0 0.0 3.9e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KER22157.1 - 9.8e-22 77.0 0.0 2.6e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV RVT_1 PF00078.27 KER22157.1 - 4.8e-17 62.2 0.0 1.1e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU_D2 PF03144.25 KER22157.1 - 7.5e-12 45.5 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KER22157.1 - 3.2e-07 30.4 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KER22157.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KER22157.1 - 0.0041 17.3 0.0 0.034 14.4 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER22157.1 - 0.055 13.1 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 Ras family EFG_C PF00679.24 KER22158.1 - 2.1e-07 30.8 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus SK_channel PF03530.14 KER22160.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Gln-synt_C PF00120.24 KER22163.1 - 4e-16 59.0 0.0 2.3e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.24 KER22165.1 - 6.1e-17 61.6 0.0 2.1e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KER22165.1 - 1e-11 44.4 0.0 2.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Peptidase_M1 PF01433.20 KER22166.1 - 3.3e-83 278.5 0.0 5.2e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KER22166.1 - 3.5e-53 181.2 0.0 5.1e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KER22166.1 - 9.3e-39 133.5 0.5 2.8e-36 125.4 0.0 2.6 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain zf-C4 PF00105.18 KER22168.1 - 1.4e-15 57.4 7.0 8.5e-09 35.7 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 KER22168.1 - 0.97 9.6 4.2 1.2 9.2 2.6 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Lectin_C PF00059.21 KER22169.1 - 3.3e-06 27.8 0.1 8.5e-06 26.5 0.1 1.7 2 1 0 2 2 2 1 Lectin C-type domain Dymeclin PF09742.9 KER22170.1 - 2.6e-85 287.1 12.4 3.2e-85 286.8 12.4 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 KER22170.1 - 1.2e-05 23.7 12.9 7.7e-05 21.0 11.4 2.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein NHL PF01436.21 KER22172.1 - 0.023 14.7 0.5 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 NHL repeat Ig_3 PF13927.6 KER22177.1 - 2.5e-22 79.3 9.4 2.9e-08 34.2 0.1 7.0 6 1 0 6 6 6 5 Immunoglobulin domain C2-set_2 PF08205.12 KER22177.1 - 2.6e-14 53.0 5.4 0.0058 16.7 0.7 7.0 7 0 0 7 7 7 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 KER22177.1 - 3.2e-10 40.2 8.6 2.3e-05 24.6 0.1 6.0 6 1 0 6 6 6 2 Immunoglobulin domain ig PF00047.25 KER22177.1 - 1.6e-09 37.8 3.8 0.00017 21.7 0.0 6.2 6 1 0 6 6 6 1 Immunoglobulin domain I-set PF07679.16 KER22177.1 - 2.4e-09 37.1 0.0 0.00079 19.4 0.0 5.8 7 0 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.15 KER22177.1 - 5e-05 23.6 1.0 26 5.3 0.0 6.1 6 0 0 6 6 6 0 Immunoglobulin C1-set domain V-set PF07686.17 KER22177.1 - 0.0098 16.1 3.0 1.7 8.8 0.3 4.9 5 1 0 5 5 5 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 KER22177.1 - 0.01 14.7 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E 7tm_1 PF00001.21 KER22178.1 - 1.7e-68 230.8 8.5 2.4e-68 230.3 8.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER22178.1 - 0.0028 17.1 14.4 0.15 11.5 0.4 3.8 3 1 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER22178.1 - 0.0049 16.5 1.8 0.0049 16.5 1.8 2.5 4 0 0 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KER22178.1 - 0.08 12.2 14.0 0.057 12.7 8.3 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4199 PF13858.6 KER22178.1 - 4.3 7.7 9.4 0.12 12.8 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Pkinase PF00069.25 KER22179.1 - 3.7e-60 203.5 0.0 4.9e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22179.1 - 2.4e-22 79.4 0.0 3.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.14 KER22180.1 - 5.1e-55 187.0 7.9 2.7e-19 69.0 0.4 4.0 1 1 3 4 4 4 4 CDC45-like protein Ras PF00071.22 KER22181.1 - 8.2e-16 58.0 0.0 1.5e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER22181.1 - 2.3e-06 27.8 0.0 1.6e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KER22181.1 - 1.6e-05 25.0 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER22181.1 - 2.9e-05 23.7 0.0 0.00046 19.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KER22181.1 - 0.0014 18.1 0.0 0.01 15.3 0.0 2.3 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER22181.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NOG1 PF06858.14 KER22181.1 - 0.068 13.0 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 KER22181.1 - 0.074 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SNF2_N PF00176.23 KER22182.1 - 8e-52 176.1 0.6 1.2e-51 175.5 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER22182.1 - 3e-20 72.6 0.0 2.9e-18 66.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER22182.1 - 5.3e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 KER22182.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sulfate_transp PF00916.20 KER22183.1 - 1.4e-54 185.3 11.3 1.4e-54 185.3 11.3 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KER22183.1 - 1.3e-06 28.0 0.0 3.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 STAS domain PGG PF13962.6 KER22183.1 - 2.2 8.1 10.0 0.36 10.7 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function MFS_MOT1 PF16983.5 KER22183.1 - 4.9 7.6 9.1 1.9 8.9 4.5 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Ctr PF04145.15 KER22183.1 - 8.7 7.0 10.0 1.7 9.2 0.2 3.1 3 0 0 3 3 3 0 Ctr copper transporter family GMC_oxred_N PF00732.19 KER22184.1 - 0.00017 21.1 0.0 0.025 13.9 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase RHD_DNA_bind PF00554.22 KER22187.1 - 5.7e-21 75.2 0.0 2.5e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Rel homology DNA-binding domain RHD_dimer PF16179.5 KER22187.1 - 1.2e-10 41.3 0.1 1.5e-05 24.9 0.0 2.8 3 0 0 3 3 3 2 Rel homology dimerisation domain TIG PF01833.24 KER22187.1 - 0.0012 18.9 0.0 0.0063 16.6 0.0 2.5 1 0 0 1 1 1 1 IPT/TIG domain PDEase_I PF00233.19 KER22188.1 - 4.7e-86 288.4 0.8 7.4e-86 287.7 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KER22188.1 - 2.8e-28 98.9 0.4 6.7e-28 97.7 0.4 1.7 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) PDE4_UCR PF18100.1 KER22189.1 - 2.2e-07 31.5 0.3 4.1e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) Mito_carr PF00153.27 KER22190.1 - 4.4e-59 196.4 0.9 3.6e-22 78.1 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Tetraspanin PF00335.20 KER22193.1 - 0.023 14.4 17.5 0.88 9.2 17.5 2.8 1 1 0 1 1 1 0 Tetraspanin family Jnk-SapK_ap_N PF09744.9 KER22195.1 - 0.0052 17.0 1.6 0.017 15.3 1.6 1.9 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.20 KER22195.1 - 0.052 13.5 0.5 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit QVR PF17064.5 KER22195.1 - 0.22 11.8 4.4 0.6 10.4 4.4 1.8 1 0 0 1 1 1 0 Sleepless protein Serglycin PF04360.12 KER22203.1 - 0.02 14.8 0.2 0.044 13.7 0.2 1.5 1 0 0 1 1 1 0 Serglycin Inj_translocase PF16928.5 KER22203.1 - 0.051 13.0 0.6 0.096 12.1 0.6 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome PCI PF01399.27 KER22206.1 - 9.2e-08 32.6 0.1 1.9e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 PCI domain LMBR1 PF04791.16 KER22206.1 - 0.0037 16.3 0.1 0.0052 15.8 0.1 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein VEFS-Box PF09733.9 KER22207.1 - 4.1e-30 104.4 0.0 7e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF1091 PF06477.13 KER22211.1 - 0.026 15.0 2.0 0.52 10.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1091) oligo_HPY PF08352.12 KER22211.1 - 0.043 14.3 0.0 73 4.0 0.0 3.9 4 0 0 4 4 4 0 Oligopeptide/dipeptide transporter, C-terminal region Lectin_C PF00059.21 KER22211.1 - 0.083 13.6 0.1 71 4.2 0.0 3.3 3 0 0 3 3 3 0 Lectin C-type domain AflR PF08493.10 KER22211.1 - 0.13 11.7 4.9 1.3 8.4 0.1 3.0 1 1 0 3 3 3 0 Aflatoxin regulatory protein Homeodomain PF00046.29 KER22214.1 - 5.9e-10 38.8 2.0 1.2e-09 37.8 2.0 1.6 1 0 0 1 1 1 1 Homeodomain Sgf11 PF08209.11 KER22214.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) RhoGAP PF00620.27 KER22215.1 - 2.2e-33 115.2 0.0 3.8e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain START PF01852.19 KER22215.1 - 3.8e-11 42.8 0.6 8.9e-11 41.6 0.6 1.5 1 0 0 1 1 1 1 START domain RVT_1 PF00078.27 KER22224.1 - 9.8e-08 31.8 0.1 3.3e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCIP PF13862.6 KER22225.1 - 7.7e-22 78.1 0.0 8.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein P2 PF07194.11 KER22225.1 - 0.12 12.5 0.2 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 P2 response regulator binding domain zf-C2H2 PF00096.26 KER22226.1 - 0.00047 20.5 0.3 0.0017 18.7 0.1 2.2 1 1 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22226.1 - 0.0018 18.9 0.6 0.0018 18.9 0.6 2.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-BED PF02892.15 KER22226.1 - 0.011 15.7 0.4 0.028 14.4 0.4 1.6 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.6 KER22226.1 - 0.012 15.6 0.4 0.028 14.4 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER22226.1 - 0.021 15.1 0.1 0.046 14.0 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KER22226.1 - 0.093 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SAE2 PF08573.10 KER22226.1 - 0.095 13.8 0.2 3.8 8.7 0.0 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Zn_Tnp_IS1595 PF12760.7 KER22226.1 - 0.16 12.0 2.6 0.33 11.0 2.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OB_Dis3 PF17849.1 KER22226.1 - 0.17 11.9 0.4 0.94 9.5 0.1 2.3 3 0 0 3 3 3 0 Dis3-like cold-shock domain 2 (CSD2) TPR_11 PF13414.6 KER22227.1 - 4.3e-14 51.9 0.0 0.00043 19.9 0.0 3.6 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.17 KER22227.1 - 1.5e-13 49.7 11.1 0.0082 16.2 0.0 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER22227.1 - 1e-10 41.5 11.0 0.00059 20.4 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER22227.1 - 1.3e-10 40.9 2.2 0.14 12.6 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER22227.1 - 1.1e-09 38.7 10.0 9.2e-05 23.0 0.2 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER22227.1 - 2.2e-09 37.3 0.6 0.17 12.0 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER22227.1 - 3.6e-08 32.9 10.7 0.0088 15.8 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER22227.1 - 1e-07 32.3 6.2 0.00027 21.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KER22227.1 - 9.7e-05 21.7 0.7 0.036 13.3 0.0 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER22227.1 - 0.00032 20.5 0.7 2.3 8.4 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER22227.1 - 0.00082 19.4 12.8 1.7 9.1 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 KER22227.1 - 0.0034 17.7 1.0 0.021 15.1 0.0 2.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER22227.1 - 0.0045 17.2 10.7 10 6.5 0.3 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER22227.1 - 0.026 15.2 8.1 1.3 9.8 0.3 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Asp PF00026.23 KER22231.1 - 1.1e-38 133.5 0.0 1.3e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER22231.1 - 9.4e-09 35.8 1.2 1.9e-05 25.0 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal RPAP1_C PF08620.10 KER22232.1 - 2.6e-24 85.1 0.1 5.5e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KER22232.1 - 2.6e-13 49.5 3.3 5.2e-13 48.5 3.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal GOLGA2L5 PF15070.6 KER22234.1 - 2e-24 86.3 61.8 2e-24 86.3 61.8 3.1 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Macoilin PF09726.9 KER22234.1 - 0.00046 18.9 10.6 0.00046 18.9 10.6 3.1 2 1 1 3 3 3 1 Macoilin family DUF1722 PF08349.11 KER22234.1 - 0.16 12.2 8.7 0.13 12.5 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) AMPK1_CBM PF16561.5 KER22236.1 - 7.5e-30 103.0 0.5 2e-29 101.6 0.4 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KER22236.1 - 3.4e-24 84.9 1.7 8.4e-24 83.6 1.7 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 KER22236.1 - 0.0092 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ERG4_ERG24 PF01222.17 KER22239.1 - 4.5e-21 75.1 0.1 4.9e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KER22239.1 - 0.00012 22.4 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KER22239.1 - 0.00023 21.5 0.2 0.00041 20.7 0.1 1.5 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KER22239.1 - 0.00031 20.3 0.5 0.00035 20.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SOCS_box PF07525.16 KER22240.1 - 4.1e-05 23.8 4.8 0.00012 22.3 4.8 1.9 1 0 0 1 1 1 1 SOCS box CCDC24 PF15669.5 KER22240.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family HlyIII PF03006.20 KER22245.1 - 1.3e-06 28.4 6.6 1.9e-06 27.8 6.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related Malic_M PF03949.15 KER22247.1 - 6.8e-76 254.9 0.0 9e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KER22247.1 - 1.6e-72 243.1 0.0 2.4e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Dymeclin PF09742.9 KER22249.1 - 0.065 11.6 0.0 0.08 11.4 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Gly-rich_Ago1 PF12764.7 KER22249.1 - 0.4 11.5 4.7 0.72 10.7 0.8 2.7 3 1 0 3 3 3 0 Glycine-rich region of argonaut Sox_N PF12444.8 KER22249.1 - 3.3 8.9 6.6 0.83 10.8 1.7 2.5 1 1 2 3 3 3 0 Sox developmental protein N terminal Lebercilin PF15619.6 KER22250.1 - 5.4e-20 71.9 33.3 1.3e-19 70.6 33.3 1.6 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Ssu72 PF04722.13 KER22250.1 - 0.01 15.4 1.8 0.042 13.4 2.2 1.7 2 0 0 2 2 2 1 Ssu72-like protein CENP-F_leu_zip PF10473.9 KER22250.1 - 0.069 13.2 23.4 0.89 9.6 5.0 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3347 PF11827.8 KER22250.1 - 0.083 13.1 9.3 2.4 8.3 6.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Bcr-Abl_Oligo PF09036.10 KER22250.1 - 0.51 10.4 11.0 0.96 9.5 0.1 3.9 2 2 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Cnn_1N PF07989.11 KER22250.1 - 2.3 8.4 21.4 5.9 7.1 1.1 3.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Sec2p PF06428.11 KER22250.1 - 3.3 7.8 25.5 7.4 6.6 4.9 4.0 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 KER22250.1 - 3.3 7.8 34.3 3.1 7.9 3.5 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 KER22250.1 - 3.6 7.3 23.0 2.5 7.8 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF4407 PF14362.6 KER22250.1 - 5.1 6.4 22.4 13 5.0 21.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tmemb_cc2 PF10267.9 KER22250.1 - 6.3 5.8 26.6 0.055 12.6 11.1 2.9 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Spc7 PF08317.11 KER22250.1 - 6.7 5.5 28.4 1.7 7.4 10.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein SDA1 PF05285.12 KER22251.1 - 0.00017 21.2 25.7 0.00019 21.0 25.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 KER22251.1 - 0.043 13.2 28.6 0.051 12.9 28.6 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 KER22251.1 - 0.18 10.2 27.2 0.18 10.2 27.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4795 PF16043.5 KER22252.1 - 2e-20 73.3 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) GAPES4 PF17157.4 KER22252.1 - 0.1 13.0 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain DNA_pol3_delta PF06144.13 KER22252.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_13 PF13166.6 KER22253.1 - 0.05 12.2 1.9 0.074 11.7 1.9 1.3 1 0 0 1 1 1 0 AAA domain BAR PF03114.18 KER22253.1 - 0.056 13.1 0.3 0.056 13.1 0.3 3.2 3 1 1 4 4 4 0 BAR domain HisKA PF00512.25 KER22253.1 - 0.079 13.0 0.5 1 9.4 0.1 2.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Prefoldin_2 PF01920.20 KER22253.1 - 0.17 11.9 15.0 1.4 8.9 1.4 4.0 4 0 0 4 4 4 0 Prefoldin subunit Sds3 PF08598.11 KER22253.1 - 0.17 11.9 6.4 1.8 8.5 0.7 2.5 2 1 0 2 2 2 0 Sds3-like HSBP1 PF06825.12 KER22253.1 - 0.23 11.3 10.1 12 5.8 0.1 4.8 5 0 0 5 5 5 0 Heat shock factor binding protein 1 TolA_bind_tri PF16331.5 KER22253.1 - 0.25 11.4 12.1 5.4 7.2 0.5 4.4 4 1 0 4 4 4 0 TolA binding protein trimerisation GAS PF13851.6 KER22253.1 - 0.35 10.2 10.7 0.077 12.3 0.7 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.17 KER22253.1 - 0.42 10.5 14.5 0.71 9.8 0.2 4.1 5 0 0 5 5 4 0 Prefoldin subunit TSC22 PF01166.18 KER22253.1 - 0.57 10.5 7.4 18 5.7 0.4 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family Synaptobrevin PF00957.21 KER22253.1 - 0.59 10.0 2.2 16 5.4 0.1 3.2 3 0 0 3 3 3 0 Synaptobrevin DUF1043 PF06295.12 KER22253.1 - 1 9.3 4.7 14 5.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF2203 PF09969.9 KER22253.1 - 1.2 9.8 4.1 2.2 9.0 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 KER22253.1 - 1.5 8.6 9.2 2.8 7.7 0.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF724) Enkurin PF13864.6 KER22253.1 - 2.8 8.4 9.6 4.9 7.7 0.3 3.4 3 0 0 3 3 3 0 Calmodulin-binding DUF4795 PF16043.5 KER22253.1 - 3.3 7.3 17.6 12 5.4 3.7 3.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4795) FapA PF03961.13 KER22253.1 - 3.5 6.1 8.6 2.2 6.8 1.1 2.7 1 1 1 3 3 3 0 Flagellar Assembly Protein A DUF948 PF06103.11 KER22253.1 - 3.6 7.9 4.6 6.8 7.0 0.5 2.8 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KER22253.1 - 3.7 7.6 8.3 0.95 9.5 1.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KER22253.1 - 4.4 7.2 12.6 16 5.4 0.9 4.4 4 0 0 4 4 4 0 Septum formation initiator IFP_35_N PF07334.13 KER22253.1 - 4.9 7.3 9.0 16 5.6 0.4 3.3 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus MHC2-interact PF09307.10 KER22253.1 - 5.2 7.1 7.3 1.1 9.2 1.1 2.5 3 0 0 3 3 2 0 CLIP, MHC2 interacting BLOC1_2 PF10046.9 KER22253.1 - 5.5 7.4 10.8 2.7 8.4 0.2 3.7 4 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 KER22253.1 - 6.5 6.4 12.0 1.7 8.3 0.8 3.1 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 Fzo_mitofusin PF04799.13 KER22253.1 - 7.5 6.1 7.7 5.9 6.4 0.3 3.4 3 1 1 4 4 4 0 fzo-like conserved region DegS PF05384.11 KER22253.1 - 7.7 6.0 17.1 20 4.6 0.0 4.3 2 2 0 4 4 4 0 Sensor protein DegS Snf7 PF03357.21 KER22256.1 - 2.3e-39 134.8 13.6 2.8e-39 134.5 13.6 1.1 1 0 0 1 1 1 1 Snf7 LRR_8 PF13855.6 KER22259.1 - 2.2e-46 155.4 37.7 5.9e-09 35.6 1.5 7.3 5 2 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KER22259.1 - 3.6e-31 106.7 49.4 6.2e-06 26.5 0.2 9.6 6 3 3 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER22259.1 - 3e-13 49.6 17.6 0.00097 18.7 0.7 5.5 4 2 2 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 KER22259.1 - 6.8e-11 41.1 39.7 0.99 10.2 0.1 13.5 15 0 0 15 15 15 5 Leucine Rich Repeat LRR_6 PF13516.6 KER22259.1 - 2.9e-10 39.3 41.9 0.036 14.1 0.2 12.4 13 0 0 13 13 13 4 Leucine Rich repeat LELP1 PF15042.6 KER22259.1 - 0.012 16.0 1.4 0.032 14.6 1.4 1.7 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 gag_pre-integrs PF13976.6 KER22259.1 - 0.038 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain Coprogen_oxidas PF01218.18 KER22261.1 - 2.3e-139 463.2 0.1 2.6e-139 463.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase WD40 PF00400.32 KER22262.1 - 2.7e-13 50.2 0.4 0.01 16.7 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22262.1 - 2.8e-05 24.3 0.0 0.65 10.3 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Smr PF01713.21 KER22263.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Smr domain LapA_dom PF06305.11 KER22263.1 - 0.4 10.5 1.6 0.48 10.3 0.5 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PCNA_N PF00705.18 KER22264.1 - 8.6e-55 183.9 1.9 1.6e-54 183.0 1.9 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KER22264.1 - 2.6e-53 179.6 0.4 9.4e-53 177.8 0.1 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KER22264.1 - 1.2e-08 34.4 1.1 9.1e-06 24.9 1.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KER22264.1 - 2.1e-06 27.4 0.1 2.5e-06 27.1 0.1 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KER22264.1 - 0.00026 20.2 0.0 0.00043 19.5 0.0 1.4 1 1 0 1 1 1 1 Hus1-like protein Myco_19_kDa PF05481.12 KER22264.1 - 0.11 12.8 0.0 9.2 6.6 0.0 2.7 2 1 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen 5_nucleotid_C PF02872.18 KER22265.1 - 1.1e-36 126.5 0.0 1.7e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KER22265.1 - 9.1e-09 36.1 0.1 1.8e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L18p PF00861.22 KER22265.1 - 0.058 13.8 0.9 0.12 12.8 0.9 1.4 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Glyoxalase_5 PF14696.6 KER22265.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal ETF_alpha PF00766.19 KER22266.1 - 7e-38 128.5 0.3 1.5e-37 127.4 0.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KER22266.1 - 9.9e-24 84.2 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF1279 PF06916.13 KER22267.1 - 5.9e-11 42.8 0.2 9.4e-11 42.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) fn3 PF00041.21 KER22268.1 - 2e-14 53.7 0.1 6.3e-05 23.3 0.0 3.4 3 1 0 3 3 3 3 Fibronectin type III domain Interfer-bind PF09294.10 KER22268.1 - 1.7e-05 25.1 0.3 0.97 9.8 0.0 3.2 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KER22268.1 - 6.9e-05 23.4 1.0 1.2 9.8 0.0 3.7 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain LIFR_D2 PF17971.1 KER22268.1 - 0.067 13.4 0.8 1.5 9.0 0.1 2.6 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain DUF2369 PF10179.9 KER22268.1 - 0.13 12.7 0.1 1.7 9.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) fn3 PF00041.21 KER22269.1 - 1.6e-11 44.4 0.0 2.4e-07 31.0 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER22269.1 - 0.00064 20.2 0.8 0.0049 17.4 0.8 2.5 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KER22269.1 - 0.0012 19.1 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III PhoD_N PF16655.5 KER22269.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Galactosyl_T PF01762.21 KER22270.1 - 2.9e-24 86.0 0.0 3.5e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase RRM_1 PF00076.22 KER22271.1 - 3e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 KER22271.1 - 0.052 13.7 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NOPS (NUC059) domain RRF PF01765.19 KER22272.1 - 3.2e-06 27.2 0.0 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 2 Ribosome recycling factor Actin PF00022.19 KER22274.1 - 7.7e-28 97.2 0.0 8.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 KER22275.1 - 6.6e-83 278.6 0.0 3e-82 276.4 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER22276.1 - 2.1e-113 379.0 0.0 7.2e-113 377.3 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER22277.1 - 3.2e-138 460.7 0.0 2.9e-136 454.3 0.0 2.6 1 1 0 1 1 1 1 Actin LSDAT_euk PF18139.1 KER22279.1 - 1.1e-75 254.5 0.0 1.7e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 KER22279.1 - 1.2e-08 34.4 0.0 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote SOUL PF04832.12 KER22280.1 - 1.1e-12 48.5 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein DUF4121 PF13497.6 KER22280.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF4509 PF14970.6 KER22281.1 - 0.024 14.5 0.1 0.024 14.5 0.1 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4509) Gly_radical PF01228.21 KER22281.1 - 0.12 12.9 2.4 0.26 11.9 0.0 2.5 3 0 0 3 3 3 0 Glycine radical GST_C PF00043.25 KER22284.1 - 1.9e-09 37.6 0.0 4.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER22284.1 - 7e-09 35.9 0.0 4.2e-08 33.4 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KER22284.1 - 8.4e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER22284.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Formyl_trans_N PF00551.19 KER22286.1 - 5.1e-18 65.4 0.0 1.5e-17 63.9 0.0 1.7 1 1 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 KER22286.1 - 0.0036 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Innexin PF00876.18 KER22288.1 - 5.7e-123 410.7 0.4 4.3e-107 358.4 0.1 2.0 2 0 0 2 2 2 2 Innexin DDDD PF10161.9 KER22289.1 - 7.5e-22 76.9 0.0 8.5e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 Putative mitochondrial precursor protein CAP_GLY PF01302.25 KER22290.1 - 4.4e-24 84.3 0.8 7.3e-24 83.6 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KER22290.1 - 1e-18 67.6 0.1 1.6e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2859 PF11072.8 KER22290.1 - 0.063 13.0 0.2 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) YukD PF08817.10 KER22290.1 - 0.16 12.7 0.1 0.56 10.9 0.1 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DnaJ PF00226.31 KER22291.1 - 3.1e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KER22291.1 - 4.4e-05 23.5 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 Reductase_C PF14759.6 KER22292.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Reductase C-terminal E3_UbLigase_R4 PF13764.6 KER22293.1 - 3.2e-108 363.0 0.0 8.4e-84 282.2 0.0 4.1 2 1 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 KER22293.1 - 2.4e-06 27.6 17.7 2.4e-06 27.6 17.7 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Pkinase_Tyr PF07714.17 KER22298.1 - 1.4e-71 240.8 0.0 4.9e-71 239.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER22298.1 - 1.8e-31 109.4 0.0 3.5e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 KER22298.1 - 1.6e-06 27.8 0.1 3.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER22298.1 - 1.1e-05 25.0 0.2 2.5e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain GTPase_binding PF09027.10 KER22298.1 - 5.3e-05 23.1 0.1 0.00016 21.6 0.1 1.8 1 0 0 1 1 1 1 GTPase binding SH3_1 PF00018.28 KER22298.1 - 6.4e-05 22.5 0.1 0.00012 21.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Kinase-like PF14531.6 KER22298.1 - 0.097 12.0 0.6 0.27 10.5 0.6 1.6 1 1 0 1 1 1 0 Kinase-like KBP_C PF12309.8 KER22301.1 - 0.028 14.0 0.7 0.094 12.2 0.5 1.8 2 0 0 2 2 2 0 KIF-1 binding protein C terminal KBP_C PF12309.8 KER22302.1 - 9.8e-81 272.0 6.6 3.1e-64 217.8 6.0 2.1 2 0 0 2 2 2 2 KIF-1 binding protein C terminal Nodulin PF02451.15 KER22302.1 - 0.0023 17.4 0.6 2.2 7.7 0.1 2.3 2 0 0 2 2 2 2 Nodulin DUF3829 PF12889.7 KER22302.1 - 0.013 15.0 0.0 26 4.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Tn916-Xis PF09035.10 KER22302.1 - 0.035 14.3 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Excisionase from transposon Tn916 HD_4 PF13328.6 KER22302.1 - 0.091 12.5 0.9 0.21 11.3 0.9 1.5 1 0 0 1 1 1 0 HD domain TPR_6 PF13174.6 KER22302.1 - 3 8.7 5.7 18 6.2 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF733 PF05306.11 KER22306.1 - 0.74 10.2 3.7 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Thiolase_N PF00108.23 KER22309.1 - 7.8e-79 264.7 11.2 1.2e-35 123.1 0.0 4.2 3 1 1 4 4 4 4 Thiolase, N-terminal domain Thiolase_C PF02803.18 KER22309.1 - 7.4e-36 122.5 1.6 1.9e-35 121.2 0.5 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain TMEM65 PF10507.9 KER22310.1 - 7.4e-40 135.3 1.0 1.1e-39 134.7 1.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 NCBP3 PF10309.9 KER22310.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 CAP PF00188.26 KER22311.1 - 2.6e-18 67.1 0.2 3.1e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Lyase_8 PF02278.18 KER22311.1 - 0.067 12.7 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain polyprenyl_synt PF00348.17 KER22312.1 - 6.3e-50 169.6 0.0 6e-38 130.4 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase MRG PF05712.13 KER22312.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 MRG Rad10 PF03834.14 KER22314.1 - 2.5e-47 159.6 0.3 3.7e-47 159.1 0.3 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KER22314.1 - 3.6e-07 30.7 0.0 6.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KER22314.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif EspB_PE PF18625.1 KER22314.1 - 0.12 12.8 0.4 17 5.9 0.0 2.8 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain Bac_transf PF02397.16 KER22315.1 - 0.21 11.2 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase NADH_B2 PF14813.6 KER22316.1 - 9.4e-08 31.7 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Tmemb_55A PF09788.9 KER22317.1 - 1.2e-57 194.9 18.8 1.4e-36 125.9 8.5 2.0 2 0 0 2 2 2 2 Transmembrane protein 55A IBR PF01485.21 KER22317.1 - 0.009 16.2 14.4 0.059 13.6 0.2 3.9 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain HypA PF01155.19 KER22317.1 - 0.028 14.4 0.6 0.028 14.4 0.6 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 KER22317.1 - 0.33 11.0 10.7 0.64 10.1 4.4 3.2 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like RNHCP PF12647.7 KER22317.1 - 3.3 7.7 11.3 26 4.9 0.0 2.4 2 0 0 2 2 2 0 RNHCP domain zinc_ribbon_9 PF14369.6 KER22317.1 - 5.4 7.4 12.4 12 6.3 3.3 3.5 3 0 0 3 3 3 0 zinc-ribbon DUF4451 PF14616.6 KER22317.1 - 6.5 7.0 10.9 2.9 8.1 2.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4451) zinc_ribbon_4 PF13717.6 KER22317.1 - 7.3 6.6 22.8 4.4 7.3 4.4 4.8 5 1 1 6 6 6 0 zinc-ribbon domain Glyco_hydro_20 PF00728.22 KER22320.1 - 3.6e-73 247.0 0.2 3.1e-72 243.9 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KER22320.1 - 5.2e-09 36.9 0.0 1e-08 35.9 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KER22320.1 - 0.0087 16.8 0.0 0.016 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 KER22320.1 - 0.031 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DUF898 PF05987.13 KER22320.1 - 0.032 13.3 1.9 0.056 12.5 1.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Toxin_8 PF07365.12 KER22322.1 - 0.13 12.5 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Alpha conotoxin precursor tRNA_deacylase PF04414.12 KER22323.1 - 0.098 12.2 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase G-alpha PF00503.20 KER22324.1 - 1.4e-79 267.9 4.5 6.2e-67 226.2 0.1 2.5 1 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KER22324.1 - 5.8e-13 48.7 1.6 3.9e-12 46.0 0.1 2.6 2 1 1 3 3 3 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER22324.1 - 0.0046 16.4 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KER22324.1 - 0.039 14.2 0.1 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sod_Cu PF00080.20 KER22326.1 - 2.3e-11 44.0 0.0 3.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TMEM208_SND2 PF05620.11 KER22330.1 - 3.6e-44 150.5 0.3 4.1e-44 150.3 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3742 PF12553.8 KER22330.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) AAA_16 PF13191.6 KER22332.1 - 7.3e-05 23.2 0.0 0.00026 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KER22332.1 - 0.0001 22.6 0.0 0.00035 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KER22332.1 - 0.001 19.1 0.0 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KER22332.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KER22332.1 - 0.022 15.1 0.2 0.19 12.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Toxin_34 PF08396.10 KER22333.1 - 0.009 16.8 4.0 0.022 15.5 4.0 1.6 1 0 0 1 1 1 1 Spider toxin omega agatoxin/Tx1 family Homeobox_KN PF05920.11 KER22335.1 - 1.8e-15 56.5 1.1 3.6e-15 55.6 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KER22335.1 - 6.8e-07 29.0 0.8 1.5e-06 27.9 0.8 1.7 1 0 0 1 1 1 1 Homeodomain GEMIN8 PF15348.6 KER22335.1 - 0.018 15.4 2.1 0.046 14.0 2.1 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Zip PF02535.22 KER22335.1 - 0.049 12.9 0.7 0.078 12.2 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 KER22335.1 - 0.11 11.8 7.9 0.21 10.9 7.9 1.4 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 KER22335.1 - 0.2 11.2 8.9 0.41 10.2 8.9 1.4 1 0 0 1 1 1 0 PPP4R2 FYDLN_acid PF09538.10 KER22335.1 - 0.52 11.0 11.5 1.4 9.7 11.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Astro_capsid_p PF12226.8 KER22335.1 - 1 8.5 9.3 1.6 7.8 9.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 KER22335.1 - 2.4 7.9 13.7 4.9 6.8 13.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KER22335.1 - 7.9 4.6 10.9 12 3.9 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family Tetraspanin PF00335.20 KER22336.1 - 2.8e-07 30.5 0.0 4.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Tetraspanin family 7tm_1 PF00001.21 KER22337.1 - 1.4e-35 123.0 6.4 1.4e-35 123.0 6.4 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER22337.1 - 0.004 16.8 4.8 0.004 16.8 4.8 2.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF5326 PF17260.2 KER22337.1 - 0.37 11.0 7.5 6.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5326) HEAT_2 PF13646.6 KER22338.1 - 3.3e-24 85.1 13.8 4.1e-05 23.9 0.0 8.6 5 2 3 8 8 8 8 HEAT repeats HEAT PF02985.22 KER22338.1 - 1e-23 81.3 36.5 0.0061 16.7 0.1 13.7 14 0 0 14 14 14 8 HEAT repeat Vac14_Fab1_bd PF12755.7 KER22338.1 - 3.8e-06 27.4 0.1 12 6.6 0.0 6.6 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KER22338.1 - 4.9e-05 23.7 16.4 5.8 7.5 0.1 8.1 6 2 2 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 KER22338.1 - 0.0012 18.9 6.3 0.17 11.9 0.1 4.9 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KER22338.1 - 0.01 14.4 8.7 0.064 11.8 0.9 4.3 5 2 1 6 6 6 0 Adaptin N terminal region Arm PF00514.23 KER22338.1 - 0.067 13.3 1.3 34 4.7 0.0 4.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AMP-binding PF00501.28 KER22339.1 - 3.4e-54 184.0 0.0 4.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER22339.1 - 2.7e-14 53.9 0.4 7.2e-14 52.5 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACC_central PF08326.12 KER22342.1 - 3e-193 644.0 0.0 4.8e-153 511.1 0.0 2.9 2 1 0 2 2 2 2 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KER22342.1 - 7.2e-135 450.4 0.0 1.2e-133 446.4 0.0 2.1 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KER22342.1 - 2.6e-48 164.3 0.3 5.6e-48 163.2 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KER22342.1 - 2.1e-29 102.3 0.1 9.5e-29 100.2 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KER22342.1 - 2.5e-20 72.6 0.0 6.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KER22342.1 - 1.5e-06 27.9 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KER22342.1 - 0.0042 17.2 0.1 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KER22342.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Pkinase PF00069.25 KER22345.1 - 3.1e-69 233.3 0.0 3.9e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22345.1 - 5e-31 107.9 0.0 6.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER22345.1 - 3.4e-05 23.0 0.1 5.2e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER22345.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER22345.1 - 0.017 14.5 0.1 0.75 9.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KER22345.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER22345.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AMP-binding_C PF13193.6 KER22345.1 - 0.19 12.8 0.0 0.46 11.5 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KER22346.1 - 2.4e-66 224.1 0.0 3.3e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.27 KER22346.1 - 9.1e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding_C PF13193.6 KER22346.1 - 1.1e-12 48.8 0.3 2.8e-12 47.4 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KER22346.1 - 0.016 15.1 0.4 0.056 13.4 0.4 2.0 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus NARG2_C PF10505.9 KER22347.1 - 1e-16 61.2 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus START PF01852.19 KER22349.1 - 0.057 12.8 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 START domain zf-C2H2 PF00096.26 KER22350.1 - 1.9e-24 84.7 29.7 2.6e-06 27.6 0.9 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22350.1 - 2.6e-20 71.3 28.5 0.00041 20.9 0.6 6.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER22350.1 - 5.7e-17 61.3 29.5 0.00016 21.9 3.8 6.3 6 0 0 6 6 5 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER22350.1 - 1.3e-07 31.8 15.9 0.43 10.9 0.0 5.5 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER22350.1 - 1.5e-06 28.0 25.7 0.018 15.0 0.9 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER22350.1 - 1.6e-06 27.7 26.3 0.25 11.1 0.3 5.7 5 0 0 5 5 5 5 zinc-finger C2H2-type zf-BED PF02892.15 KER22350.1 - 0.0023 17.9 26.6 0.45 10.6 0.1 5.3 2 2 3 5 5 5 2 BED zinc finger Zn-ribbon_8 PF09723.10 KER22350.1 - 0.0062 16.6 18.7 0.072 13.2 1.0 4.7 3 2 2 5 5 5 3 Zinc ribbon domain zf-Di19 PF05605.12 KER22350.1 - 0.0076 16.5 22.7 0.0092 16.3 2.0 4.8 2 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 KER22350.1 - 0.011 16.4 12.8 0.22 12.3 1.2 3.2 4 0 0 4 4 2 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 KER22350.1 - 0.015 15.5 5.8 5.2 7.4 0.0 5.0 4 0 0 4 4 4 0 zinc-ribbon zf-met PF12874.7 KER22350.1 - 0.022 15.1 22.8 1.1 9.7 0.3 5.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type HypA PF01155.19 KER22350.1 - 0.033 14.2 10.7 0.11 12.6 0.5 3.4 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KER22350.1 - 0.037 13.6 10.6 3.2 7.4 0.1 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KER22350.1 - 0.077 13.1 14.4 3.6 7.7 0.1 5.2 5 0 0 5 5 5 0 XPA protein N-terminal DZR PF12773.7 KER22350.1 - 0.25 11.4 21.0 1.3e+02 2.7 0.0 4.7 2 1 0 2 2 2 0 Double zinc ribbon TerY_C PF15616.6 KER22350.1 - 0.35 11.0 6.8 0.36 10.9 0.8 2.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C2HC_2 PF13913.6 KER22350.1 - 0.4 10.6 24.3 1.9 8.5 1.5 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Ogr_Delta PF04606.12 KER22350.1 - 0.51 10.4 16.2 0.51 10.4 0.6 4.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.10 KER22350.1 - 1.4 8.7 5.9 13 5.6 0.1 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain CpXC PF14353.6 KER22350.1 - 4.5 7.3 14.0 2.3 8.3 0.1 4.4 2 2 1 3 3 3 0 CpXC protein Zn_ribbon_SprT PF17283.2 KER22350.1 - 4.8 7.2 23.5 3.7 7.5 2.5 4.6 4 1 0 4 4 3 0 SprT-like zinc ribbon domain zf-AN1 PF01428.16 KER22350.1 - 6.4 7.0 17.3 14 6.0 0.5 5.8 6 0 0 6 6 5 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.7 KER22350.1 - 7.2 6.7 27.8 27 4.8 3.9 4.6 1 1 3 4 4 4 0 Transposase zinc-ribbon domain FYVE PF01363.21 KER22350.1 - 9.1 6.5 23.6 3.9 7.7 2.2 4.0 2 1 1 3 3 2 0 FYVE zinc finger Pribosyltran PF00156.27 KER22351.1 - 8.7e-14 51.3 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KER22351.1 - 0.003 17.0 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KER22351.1 - 0.0058 16.2 0.0 0.008 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF4781 PF16013.5 KER22351.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Aldo_ket_red PF00248.21 KER22354.1 - 2.1e-29 102.7 0.0 2.5e-27 95.9 0.0 2.8 1 1 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 KER22355.1 - 3.5e-35 121.3 0.0 8.9e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER22355.1 - 3.3e-10 39.6 0.0 9.4e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KER22355.1 - 8.5e-05 22.4 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LisH PF08513.11 KER22355.1 - 0.00023 21.0 0.2 0.00069 19.5 0.2 1.9 1 0 0 1 1 1 1 LisH TIP49 PF06068.13 KER22355.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KER22355.1 - 0.0014 19.1 0.1 0.0032 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KER22355.1 - 0.0033 17.4 0.0 0.0092 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER22355.1 - 0.004 17.4 0.1 0.015 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KER22355.1 - 0.0045 16.7 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KER22355.1 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KER22355.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KER22355.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KER22355.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KER22355.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KER22355.1 - 0.034 14.7 0.3 0.15 12.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KER22355.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KER22355.1 - 0.089 12.4 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KER22355.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KER22355.1 - 0.14 11.9 0.1 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 KER22355.1 - 0.15 11.5 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Oxysterol_BP PF01237.18 KER22356.1 - 1.8e-123 412.1 0.0 5.6e-123 410.5 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.16 KER22357.1 - 1.1e-13 50.9 12.5 1.1e-13 50.9 12.5 4.7 3 1 2 5 5 5 2 Major Facilitator Superfamily CENP-B_dimeris PF09026.10 KER22357.1 - 2.5 8.6 14.6 2.8 8.4 6.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain cNMP_binding PF00027.29 KER22359.1 - 2.2e-20 72.5 0.0 7.3e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KER22360.1 - 7e-15 54.9 12.5 2.1e-14 53.3 12.5 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.10 KER22361.1 - 3.5e-24 84.1 0.1 5.9e-24 83.4 0.1 1.4 1 0 0 1 1 1 1 Ion transport protein N-terminal VD10_N PF08476.10 KER22361.1 - 0.031 13.9 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Viral D10 N-terminal DUF624 PF04854.14 KER22362.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 TSP_1 PF00090.19 KER22363.1 - 1.7e-05 24.9 7.9 9.3e-05 22.6 7.9 2.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain FXa_inhibition PF14670.6 KER22363.1 - 0.002 18.4 1.0 0.002 18.4 1.0 5.5 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 KER22363.1 - 0.009 16.3 1.7 0.009 16.3 1.7 6.1 5 1 0 5 5 5 3 EGF-like domain EGF_2 PF07974.13 KER22363.1 - 0.015 15.6 6.1 0.015 15.6 6.1 6.1 7 0 0 7 7 7 0 EGF-like domain hEGF PF12661.7 KER22363.1 - 0.041 14.5 26.4 0.044 14.4 1.2 6.0 5 0 0 5 5 5 0 Human growth factor-like EGF RANK_CRD_2 PF18278.1 KER22363.1 - 0.07 13.3 0.7 0.07 13.3 0.7 3.5 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 cEGF PF12662.7 KER22363.1 - 0.12 12.3 0.3 0.12 12.3 0.3 3.7 3 0 0 3 3 3 0 Complement Clr-like EGF-like zf-C2H2 PF00096.26 KER22364.1 - 4.8e-26 89.7 31.8 1.7e-05 25.0 0.2 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22364.1 - 1.2e-22 78.6 30.5 5.2e-05 23.7 0.3 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER22364.1 - 8.4e-17 60.8 26.7 0.0002 21.6 0.1 7.0 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER22364.1 - 7.7e-14 51.3 36.0 0.00033 20.6 0.3 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER22364.1 - 4.2e-09 36.0 29.1 0.079 12.7 0.1 5.7 6 0 0 6 6 6 5 zinc-finger C2H2-type zf-met PF12874.7 KER22364.1 - 3.3e-06 27.3 23.5 0.32 11.4 0.1 5.8 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER22364.1 - 4.5e-05 23.6 25.3 0.58 10.5 1.7 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KER22364.1 - 7.1e-05 23.1 22.6 0.18 12.1 1.8 5.0 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KER22364.1 - 0.00031 20.3 17.4 0.34 10.6 0.0 5.2 3 2 3 6 6 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KER22364.1 - 0.00043 20.2 25.7 0.24 11.5 0.5 4.9 3 2 2 5 5 5 3 BED zinc finger zf-H2C2_5 PF13909.6 KER22364.1 - 0.0027 17.4 1.2 0.0027 17.4 1.2 5.3 4 2 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KER22364.1 - 0.0037 17.9 13.8 0.36 11.5 0.6 4.1 1 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 KER22364.1 - 0.0077 16.1 13.4 2.2 8.3 0.3 4.8 5 0 0 5 5 5 1 LYAR-type C2HC zinc finger LIM PF00412.22 KER22364.1 - 0.0087 16.3 18.0 0.016 15.4 4.1 3.7 2 1 1 3 3 3 1 LIM domain ADK_lid PF05191.14 KER22364.1 - 0.018 15.0 4.7 1.1 9.3 0.1 3.9 3 2 1 4 4 4 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 KER22364.1 - 0.038 13.6 23.2 0.33 10.6 0.2 5.3 5 1 0 5 5 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KER22364.1 - 0.053 13.6 12.6 0.42 10.8 1.6 4.0 2 2 3 5 5 5 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 KER22364.1 - 0.12 12.7 11.2 0.26 11.6 0.3 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF2256 PF10013.9 KER22364.1 - 0.15 12.2 10.4 1.2 9.3 0.0 4.3 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) XPA_N PF01286.18 KER22364.1 - 0.15 12.1 17.5 1.6 8.8 0.3 4.8 5 0 0 5 5 5 0 XPA protein N-terminal CpXC PF14353.6 KER22364.1 - 0.4 10.7 14.9 3.3 7.8 0.2 4.3 1 1 3 4 4 4 0 CpXC protein zinc_ribbon_15 PF17032.5 KER22364.1 - 0.42 11.4 15.2 0.99 10.2 2.2 3.2 1 1 3 4 4 4 0 zinc-ribbon family zf_C2H2_13 PF18508.1 KER22364.1 - 0.52 10.0 4.7 17 5.1 0.3 3.1 2 1 1 3 3 3 0 Zinc finger domain GAGA PF09237.11 KER22364.1 - 1.9 8.4 7.6 14 5.6 0.2 3.8 3 1 0 3 3 3 0 GAGA factor ARS2 PF04959.13 KER22364.1 - 2 8.7 9.0 22 5.3 0.2 3.6 3 1 1 4 4 4 0 Arsenite-resistance protein 2 DZR PF12773.7 KER22364.1 - 7.9 6.6 19.3 9.3 6.4 8.1 3.6 1 1 1 2 2 2 0 Double zinc ribbon PHD_4 PF16866.5 KER22364.1 - 9.9 6.3 13.3 3.3 7.9 3.6 2.6 2 1 0 2 2 2 0 PHD-finger FAM176 PF14851.6 KER22366.1 - 0.0024 17.5 2.6 0.0034 17.1 2.6 1.2 1 0 0 1 1 1 1 FAM176 family Sigma70_ner PF04546.13 KER22366.1 - 0.0028 17.6 1.4 0.0028 17.6 1.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region NOA36 PF06524.12 KER22366.1 - 0.57 9.4 21.7 0.74 9.1 21.7 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KER22366.1 - 0.81 9.7 9.1 1.1 9.3 9.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 KER22366.1 - 1 8.4 25.8 1.2 8.2 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 KER22366.1 - 1.4 8.1 4.0 1.7 7.8 4.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KER22366.1 - 7.2 4.7 13.3 8.6 4.4 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KER22366.1 - 9 4.4 13.6 11 4.1 13.6 1.0 1 0 0 1 1 1 0 CDC45-like protein PDZ PF00595.24 KER22370.1 - 4.4e-12 46.2 0.0 8.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER22370.1 - 3.1e-07 30.1 0.0 8e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER22370.1 - 0.00081 19.7 0.1 0.0027 18.0 0.1 1.9 1 1 0 1 1 1 1 PDZ domain Zip PF02535.22 KER22371.1 - 9.3e-54 182.9 1.6 1.5e-53 182.2 1.6 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3382 PF11862.8 KER22371.1 - 0.057 13.7 0.7 0.15 12.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) HEAT PF02985.22 KER22374.1 - 5.9e-05 23.0 0.8 0.24 11.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KER22374.1 - 0.00027 21.4 0.3 4.2 8.0 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat EAR PF07897.11 KER22375.1 - 0.0089 15.6 0.6 0.023 14.3 0.6 1.6 1 0 0 1 1 1 1 Ethylene-responsive binding factor-associated repression SHQ1 PF04925.15 KER22376.1 - 2.8e-47 160.5 0.2 6.9e-47 159.3 0.2 1.7 1 0 0 1 1 1 1 SHQ1 protein zf-RING_2 PF13639.6 KER22376.1 - 3.2e-06 27.4 5.0 3.2e-06 27.4 5.0 2.3 2 0 0 2 2 2 1 Ring finger domain DUF1644 PF07800.12 KER22376.1 - 0.019 15.1 0.5 0.019 15.1 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) zf-C3HC4_2 PF13923.6 KER22376.1 - 0.043 13.7 5.0 0.14 12.0 5.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER22376.1 - 0.3 11.0 8.6 0.17 11.8 6.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER22376.1 - 1.4 8.9 10.5 0.16 11.8 5.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KER22376.1 - 2.8 8.2 12.5 0.9 9.8 8.4 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rep_fac-A_C PF08646.10 KER22377.1 - 9.8e-54 181.1 4.5 1e-51 174.5 0.5 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KER22377.1 - 7.9e-34 115.5 0.5 5.9e-32 109.5 0.1 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KER22377.1 - 5.4e-18 64.9 0.5 2.3e-15 56.5 0.5 2.9 1 1 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KER22377.1 - 1.2e-10 41.2 4.4 1.7e-09 37.5 0.1 3.7 4 1 1 5 5 5 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KER22377.1 - 0.0097 15.6 1.3 0.028 14.1 0.3 2.0 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 POT1 PF02765.17 KER22377.1 - 0.033 14.0 1.4 4.2 7.2 0.0 3.0 1 1 1 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 IBR PF01485.21 KER22377.1 - 0.31 11.3 5.3 0.68 10.2 5.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Acetyltransf_13 PF13880.6 KER22378.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase AA_permease_2 PF13520.6 KER22379.1 - 9.8e-110 367.3 181.3 1.1e-48 166.2 56.9 5.2 4 1 1 5 5 5 4 Amino acid permease AA_permease PF00324.21 KER22379.1 - 4.8e-44 150.7 150.7 1.1e-23 83.6 48.1 4.3 4 0 0 4 4 4 3 Amino acid permease Oxidored_q2 PF00420.24 KER22379.1 - 2.1e-08 33.7 28.3 0.051 13.2 2.6 7.0 4 1 1 5 5 5 4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ntox16 PF15523.6 KER22379.1 - 0.0012 19.0 0.0 8.6 6.7 0.0 3.3 3 0 0 3 3 3 1 Novel toxin 16 FAM176 PF14851.6 KER22379.1 - 0.67 9.6 5.3 25 4.5 0.2 4.6 5 0 0 5 5 5 0 FAM176 family Vps51 PF08700.11 KER22383.1 - 1.4e-18 66.8 2.8 4.8e-18 65.0 2.8 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KER22383.1 - 2.1e-09 36.5 8.2 2.5e-09 36.3 5.6 2.4 3 1 0 3 3 3 1 Dor1-like family Sec5 PF15469.6 KER22383.1 - 3.7e-09 36.7 2.6 9e-09 35.4 2.6 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps54_N PF10475.9 KER22383.1 - 3.7e-07 29.7 6.8 7e-07 28.8 6.8 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex MULE PF10551.9 KER22383.1 - 0.00059 20.2 0.1 0.0021 18.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain COG2 PF06148.11 KER22383.1 - 0.0046 17.0 2.4 0.014 15.4 2.4 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KER22383.1 - 0.012 15.8 4.2 0.026 14.7 2.5 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2884 PF11101.8 KER22383.1 - 0.013 15.1 1.6 0.19 11.2 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) AAA PF00004.29 KER22384.1 - 1.3e-30 106.5 0.0 2.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER22384.1 - 1.3e-06 28.9 0.0 0.00017 22.0 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KER22384.1 - 2.9e-06 27.3 0.0 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KER22384.1 - 3.5e-06 27.1 0.0 5.9e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KER22384.1 - 2.3e-05 23.8 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KER22384.1 - 2.4e-05 24.1 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KER22384.1 - 3e-05 24.2 0.1 0.00015 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KER22384.1 - 3.5e-05 23.6 0.0 5.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KER22384.1 - 9.1e-05 22.8 0.0 0.0014 18.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KER22384.1 - 0.00029 20.1 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 KER22384.1 - 0.00048 19.5 0.1 1.9 7.7 0.0 3.1 2 1 1 3 3 3 1 KAP family P-loop domain AAA_25 PF13481.6 KER22384.1 - 0.00054 19.6 0.1 0.083 12.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KER22384.1 - 0.0014 19.2 0.5 0.0026 18.3 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KER22384.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KER22384.1 - 0.0021 18.4 0.0 0.0068 16.8 0.0 1.9 1 1 1 2 2 2 1 RNA helicase NACHT PF05729.12 KER22384.1 - 0.0031 17.4 0.0 0.15 12.0 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KER22384.1 - 0.0046 16.5 0.0 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KER22384.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KER22384.1 - 0.01 16.2 0.1 0.028 14.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KER22384.1 - 0.015 14.6 3.2 1.3 8.3 0.0 2.6 2 1 1 3 3 3 0 KaiC AAA_24 PF13479.6 KER22384.1 - 0.021 14.5 1.0 0.031 14.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KER22384.1 - 0.026 14.4 0.9 0.85 9.5 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KER22384.1 - 0.028 13.9 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 KER22384.1 - 0.029 13.8 0.1 12 5.3 0.0 2.9 1 1 2 3 3 3 0 Bacterial TniB protein Sigma54_activat PF00158.26 KER22384.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 KER22384.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KER22384.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MCM PF00493.23 KER22384.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain Torsin PF06309.11 KER22384.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_21 PF13304.6 KER22384.1 - 0.1 12.4 0.3 16 5.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_11 PF13086.6 KER22384.1 - 0.27 11.0 1.6 0.86 9.3 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KER22385.1 - 6.6e-43 146.3 0.0 1.7e-42 145.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KER22385.1 - 3.3e-29 100.6 0.3 1.3e-28 98.7 0.1 2.2 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KER22385.1 - 1.5e-08 34.3 0.1 2.5e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 KER22385.1 - 6.9e-07 29.3 0.0 4.5e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KER22385.1 - 3.1e-06 27.7 0.0 7.9e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KER22385.1 - 1.6e-05 25.1 0.0 0.00026 21.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KER22385.1 - 2.4e-05 24.4 0.0 0.00031 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KER22385.1 - 3.1e-05 23.8 0.0 8.6e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KER22385.1 - 5.1e-05 22.6 0.0 7.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KER22385.1 - 5.9e-05 22.9 0.0 9.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KER22385.1 - 0.00017 21.9 0.0 0.0021 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KER22385.1 - 0.00037 19.7 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KER22385.1 - 0.0011 18.6 0.2 0.14 11.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 KER22385.1 - 0.0016 18.8 0.1 0.01 16.2 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KER22385.1 - 0.0019 18.8 0.0 0.0047 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER22385.1 - 0.0024 18.0 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KER22385.1 - 0.0091 15.9 0.0 0.27 11.1 0.0 2.3 1 1 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 KER22385.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KER22385.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KER22385.1 - 0.016 14.9 0.0 0.054 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 KER22385.1 - 0.017 15.6 0.0 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KER22385.1 - 0.019 14.3 4.0 2 7.7 0.0 3.1 3 1 1 4 4 4 0 KaiC KAP_NTPase PF07693.14 KER22385.1 - 0.025 13.8 0.6 4.4 6.4 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain Sigma54_activat PF00158.26 KER22385.1 - 0.029 14.1 0.0 0.12 12.0 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KER22385.1 - 0.033 13.6 0.1 0.15 11.5 0.1 2.1 2 1 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KER22385.1 - 0.056 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KER22385.1 - 0.081 12.8 1.0 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KER22385.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KER22385.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin Ephrin_rec_like PF07699.13 KER22386.1 - 2.4e-07 30.4 4.0 5.9e-05 22.7 0.3 3.3 3 0 0 3 3 3 2 Putative ephrin-receptor like MAP65_ASE1 PF03999.12 KER22386.1 - 0.081 11.6 0.4 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.31 KER22387.1 - 1.1e-28 99.1 0.2 1.9e-28 98.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain PTP_N PF12453.8 KER22387.1 - 0.34 10.7 1.8 0.97 9.2 1.8 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal DUF4735 PF15882.5 KER22390.1 - 3.6e-66 223.6 0.2 4.1e-66 223.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) C2 PF00168.30 KER22391.1 - 4.4e-18 65.5 0.9 6.7e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KER22391.1 - 4.8e-05 23.6 7.4 0.00011 22.4 7.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 KER22391.1 - 0.05 13.7 5.8 0.14 12.4 5.8 1.7 1 0 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 KER22391.1 - 2.6 7.8 9.5 0.4 10.3 4.6 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Ank PF00023.30 KER22392.1 - 1.7e-15 56.7 6.2 1.4e-05 25.3 0.5 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KER22392.1 - 2.4e-15 56.9 0.5 6.7e-10 39.4 0.3 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER22392.1 - 1.1e-12 48.2 0.7 6.5e-07 29.8 0.3 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER22392.1 - 1.5e-12 47.5 3.9 3.3e-07 30.4 0.4 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER22392.1 - 1.6e-11 43.3 0.7 0.0012 19.1 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat CLZ PF16526.5 KER22392.1 - 0.0021 18.4 1.7 0.0049 17.2 1.7 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PapD-like PF14874.6 KER22394.1 - 0.003 17.7 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 KER22395.1 - 3.4e-14 52.8 13.4 0.00037 20.6 0.0 10.1 10 0 0 10 10 10 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CH PF00307.31 KER22395.1 - 3.2e-08 33.7 0.1 7.6e-07 29.3 0.0 3.3 4 0 0 4 4 4 1 Calponin homology (CH) domain TMEM131_like PF12371.8 KER22395.1 - 6e-06 26.4 1.3 0.27 11.5 0.0 5.6 6 0 0 6 6 6 2 Transmembrane protein 131-like CAMSAP_CH PF11971.8 KER22395.1 - 0.012 15.4 0.1 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 CAMSAP CH domain CH_2 PF06294.11 KER22395.1 - 0.17 12.0 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 CH-like domain in sperm protein Motile_Sperm PF00635.26 KER22395.1 - 1.1 9.1 10.2 3.5 7.5 0.3 5.7 7 0 0 7 7 7 0 MSP (Major sperm protein) domain Ribosomal_L38e PF01781.18 KER22396.1 - 1.3e-19 70.0 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L38e protein family Las1 PF04031.13 KER22396.1 - 1.5e-10 41.4 0.0 3.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Las1-like RRS1 PF04939.12 KER22397.1 - 3.2e-36 124.6 9.4 5.5e-34 117.4 9.4 2.6 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RVT_1 PF00078.27 KER22397.1 - 0.0012 18.4 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3656 PF12392.8 KER22397.1 - 0.1 13.2 0.3 0.24 12.1 0.3 1.6 1 0 0 1 1 1 0 Collagenase F-box-like PF12937.7 KER22399.1 - 7.8e-11 41.7 0.5 7.8e-11 41.7 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER22399.1 - 0.00013 21.7 0.3 0.00013 21.7 0.3 2.3 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KER22399.1 - 0.0043 16.6 0.2 0.0098 15.5 0.2 1.6 1 0 0 1 1 1 1 F-box RPN13_C PF16550.5 KER22399.1 - 0.089 13.0 0.9 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 UCH-binding domain DUF1283 PF06932.11 KER22401.1 - 0.0023 18.1 0.1 0.0028 17.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) DUF3905 PF13045.6 KER22402.1 - 2.5e-09 37.0 55.4 61 3.7 0.1 20.3 1 1 17 21 21 21 0 Protein of unknown function (DUF3905) H-kinase_dim PF02895.14 KER22402.1 - 4.5e-05 23.7 87.3 73 3.9 0.3 21.9 23 0 0 23 23 23 0 Signal transducing histidine kinase, homodimeric domain PTE PF02126.18 KER22402.1 - 1.2 8.5 65.4 1.3e+02 1.9 0.0 19.4 21 0 0 21 21 21 0 Phosphotriesterase family EnY2 PF10163.9 KER22407.1 - 0.06 13.7 0.1 0.39 11.1 0.1 2.0 1 1 0 1 1 1 0 Transcription factor e(y)2 ARL2_Bind_BART PF11527.8 KER22408.1 - 9.3e-11 41.9 0.5 1.3e-10 41.4 0.5 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART EF-hand_7 PF13499.6 KER22409.1 - 2.7e-22 79.0 1.1 9.1e-10 38.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KER22409.1 - 2.8e-21 73.4 4.7 1.8e-05 23.9 0.1 5.2 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 KER22409.1 - 4.7e-21 72.9 1.0 2.8e-05 23.7 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KER22409.1 - 7e-15 53.8 1.4 0.00021 20.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KER22409.1 - 2.2e-14 53.1 0.5 1e-08 34.9 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair Scytalone_dh PF02982.14 KER22409.1 - 0.022 14.5 0.5 0.048 13.5 0.1 1.7 2 0 0 2 2 2 0 Scytalone dehydratase RPAP2_Rtr1 PF04181.13 KER22411.1 - 2.4e-20 72.6 0.6 8e-20 70.9 0.6 2.0 1 0 0 1 1 1 1 Rtr1/RPAP2 family zf-CCCH PF00642.24 KER22411.1 - 1.2e-09 37.8 2.1 3.7e-09 36.3 2.1 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DnaJ PF00226.31 KER22411.1 - 8.7e-08 32.2 0.1 2.3e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.6 KER22411.1 - 1.1e-07 31.6 7.0 2.7e-07 30.3 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER22411.1 - 1.8e-06 27.7 9.0 4.5e-06 26.4 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER22411.1 - 3.1e-06 27.1 5.5 9.9e-06 25.5 5.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KER22411.1 - 3.5e-06 26.9 3.5 1.2e-05 25.2 3.5 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-RING_5 PF14634.6 KER22411.1 - 8e-06 25.7 11.9 9.5e-06 25.5 10.1 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER22411.1 - 2.4e-05 24.1 9.4 6e-05 22.8 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER22411.1 - 6.1e-05 23.3 7.9 0.00023 21.5 7.9 2.1 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KER22411.1 - 0.00015 21.5 1.9 0.00015 21.5 1.9 2.7 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_10 PF16685.5 KER22411.1 - 0.00046 20.3 5.3 0.0014 18.7 5.3 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KER22411.1 - 0.0027 17.6 4.5 0.0027 17.6 4.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 KER22411.1 - 0.094 13.2 2.2 0.34 11.5 2.2 2.1 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 KER22411.1 - 0.2 11.9 11.4 0.058 13.6 7.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KER22411.1 - 0.22 11.4 3.7 0.64 9.9 3.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LCM PF04072.14 KER22412.1 - 3.7e-15 56.4 0.0 1.6e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase RVT_1 PF00078.27 KER22412.1 - 1.3e-12 47.7 0.0 5.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Rhabdo_ncap PF00945.18 KER22415.1 - 0.2 10.5 0.2 0.23 10.3 0.2 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein NTP_transf_7 PF07984.12 KER22416.1 - 3.4e-109 365.0 0.1 1.1e-86 291.1 0.0 2.6 3 0 0 3 3 3 2 Nucleotidyltransferase Sulfotransfer_4 PF17784.1 KER22417.1 - 1.4e-62 211.3 0.0 1.7e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER22417.1 - 0.0039 17.6 0.0 1.5 9.2 0.0 2.7 1 1 1 2 2 2 2 Sulfotransferase family Transket_pyr PF02779.24 KER22418.1 - 2.1e-35 122.0 0.0 3.5e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KER22418.1 - 6.5e-34 116.5 0.0 1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain Actin PF00022.19 KER22421.1 - 2.7e-151 503.8 0.0 8.7e-151 502.1 0.0 1.6 1 1 0 1 1 1 1 Actin TFIIA PF03153.13 KER22422.1 - 9.1e-05 22.6 33.5 9.1e-05 22.6 33.5 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 KER22422.1 - 0.00029 21.2 13.8 0.00029 21.2 13.8 2.2 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DDHD PF02862.17 KER22422.1 - 0.00032 20.9 5.2 0.00032 20.9 5.2 1.7 2 0 0 2 2 2 1 DDHD domain Neur_chan_memb PF02932.16 KER22422.1 - 0.003 17.6 6.9 0.003 17.6 6.9 2.1 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 KER22422.1 - 0.004 16.7 12.4 0.0059 16.1 12.4 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PcfK PF14058.6 KER22422.1 - 0.0053 17.0 15.3 0.0097 16.2 15.3 1.4 1 0 0 1 1 1 1 PcfK-like protein EPL1 PF10513.9 KER22422.1 - 0.0099 16.3 12.7 0.02 15.3 12.7 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like MDM31_MDM32 PF08118.11 KER22422.1 - 0.017 13.8 6.6 0.008 14.9 4.2 1.7 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins SID-1_RNA_chan PF13965.6 KER22422.1 - 0.021 13.2 2.6 0.03 12.7 2.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 KER22422.1 - 0.028 13.4 7.7 0.017 14.1 4.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 KER22422.1 - 0.029 14.5 9.9 0.055 13.7 9.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 KER22422.1 - 0.037 13.1 13.6 0.064 12.3 13.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 KER22422.1 - 0.038 12.7 16.6 0.058 12.2 16.6 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KER22422.1 - 0.049 11.8 13.1 0.074 11.2 13.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Serinc PF03348.15 KER22422.1 - 0.053 12.4 4.6 0.073 12.0 4.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tim54 PF11711.8 KER22422.1 - 0.068 12.0 11.5 0.13 11.0 11.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 KER22422.1 - 0.075 12.8 12.5 0.17 11.7 12.5 1.5 1 0 0 1 1 1 0 Connexin CBP_BcsG PF11658.8 KER22422.1 - 0.079 11.3 11.5 0.16 10.4 11.5 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Pex14_N PF04695.13 KER22422.1 - 0.08 13.6 28.3 0.036 14.7 25.5 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BORG_CEP PF14957.6 KER22422.1 - 0.08 14.1 5.5 0.2 12.8 5.5 1.7 1 0 0 1 1 1 0 Cdc42 effector DUF4407 PF14362.6 KER22422.1 - 0.1 11.9 17.4 0.21 10.9 17.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC53 PF10152.9 KER22422.1 - 0.16 12.4 17.1 0.33 11.4 17.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PDDEXK_6 PF04720.12 KER22422.1 - 0.16 11.9 10.6 0.033 14.1 6.8 1.8 2 0 0 2 2 1 0 PDDEXK-like family of unknown function Type2_restr_D3 PF16902.5 KER22422.1 - 0.24 11.4 2.6 20 5.2 0.0 3.0 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain PepSY_TM PF03929.16 KER22422.1 - 0.26 10.9 7.8 0.56 9.8 7.8 1.5 1 0 0 1 1 1 0 PepSY-associated TM region EMC3_TMCO1 PF01956.16 KER22422.1 - 0.29 10.9 11.6 0.58 9.9 11.6 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PIP5K PF01504.18 KER22422.1 - 0.3 10.3 11.3 0.5 9.6 11.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase TERB2 PF15101.6 KER22422.1 - 0.31 11.1 26.3 0.035 14.1 21.3 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 KER22422.1 - 0.34 9.8 24.5 0.59 9.1 24.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CLN3 PF02487.17 KER22422.1 - 0.36 9.8 13.1 0.65 9.0 13.1 1.3 1 0 0 1 1 1 0 CLN3 protein ABC2_membrane_2 PF12679.7 KER22422.1 - 0.38 10.0 2.0 0.51 9.6 2.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Eapp_C PF10238.9 KER22422.1 - 0.42 10.7 15.7 0.95 9.5 15.7 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF1764 PF08576.10 KER22422.1 - 0.43 11.5 13.8 1.2 10.1 13.8 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GBP_C PF02841.14 KER22422.1 - 0.55 9.6 25.2 0.081 12.3 21.2 1.6 2 0 0 2 2 1 0 Guanylate-binding protein, C-terminal domain DUF2828 PF11443.8 KER22422.1 - 0.57 8.2 15.7 1 7.3 15.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Zip PF02535.22 KER22422.1 - 0.63 9.2 4.8 1.1 8.4 4.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 KER22422.1 - 0.73 9.9 13.5 1.8 8.6 13.5 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family RR_TM4-6 PF06459.12 KER22422.1 - 1 9.1 17.3 1.7 8.4 17.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 KER22422.1 - 1.2 8.2 29.7 1.9 7.6 29.7 1.3 1 0 0 1 1 1 0 SprA-related family NARP1 PF12569.8 KER22422.1 - 1.2 7.9 16.9 1.8 7.4 16.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CSG2 PF16965.5 KER22422.1 - 1.8 7.5 9.0 2.7 6.8 9.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 KER22422.1 - 1.9 7.4 10.9 3 6.8 10.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Rxt3 PF08642.10 KER22422.1 - 1.9 9.2 8.9 4.7 8.0 8.9 1.7 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF4175 PF13779.6 KER22422.1 - 2.1 6.2 47.8 3.2 5.5 47.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Afi1 PF07792.12 KER22422.1 - 2.5 8.6 17.7 4.7 7.7 17.7 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1980 PF09323.10 KER22422.1 - 2.6 7.9 14.4 5.1 7.0 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) HCO3_cotransp PF00955.21 KER22422.1 - 2.6 6.7 5.2 3.9 6.2 5.2 1.2 1 0 0 1 1 1 0 HCO3- transporter family Sec62 PF03839.16 KER22422.1 - 2.7 7.5 12.7 5.1 6.5 12.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4746 PF15928.5 KER22422.1 - 2.9 7.2 12.7 5.1 6.4 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2370 PF10176.9 KER22422.1 - 3.7 7.1 8.1 6.6 6.3 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) OATP PF03137.20 KER22422.1 - 3.7 5.7 7.7 5.7 5.1 7.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0560 PF10577.9 KER22422.1 - 4.5 5.6 31.7 0.73 8.3 27.8 1.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF4638 PF15472.6 KER22422.1 - 4.7 6.9 18.6 0.57 9.9 14.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4638) CAC1F_C PF16885.5 KER22422.1 - 5.5 6.6 17.1 0.35 10.5 11.0 1.9 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term DUF327 PF03885.13 KER22422.1 - 5.8 6.9 22.8 2.1 8.3 17.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF327) FAM60A PF15396.6 KER22422.1 - 5.9 6.8 14.7 1.3 9.0 11.1 1.6 2 0 0 2 2 1 0 Protein Family FAM60A Cellulose_synt PF03552.14 KER22422.1 - 6.2 5.2 6.8 8.8 4.7 6.8 1.1 1 0 0 1 1 1 0 Cellulose synthase ALMT PF11744.8 KER22422.1 - 6.2 5.5 17.6 0.6 8.9 11.2 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter TMEM223 PF14640.6 KER22422.1 - 6.2 7.0 15.4 3.3 7.9 0.0 3.6 2 1 1 3 3 2 0 Transmembrane protein 223 Endostatin PF06482.11 KER22422.1 - 6.5 6.1 24.9 0.048 13.1 15.0 2.3 2 1 0 2 2 2 0 Collagenase NC10 and Endostatin V_ATPase_I PF01496.19 KER22422.1 - 6.7 4.5 20.9 13 3.6 20.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YjbH PF06082.11 KER22422.1 - 7.1 5.3 17.0 0.46 9.2 11.7 1.6 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Plasmodium_Vir PF05795.11 KER22422.1 - 7.7 5.8 7.7 11 5.3 7.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ATAD4 PF15321.6 KER22422.1 - 7.8 7.9 12.7 21 6.6 12.7 1.7 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF702 PF05142.12 KER22422.1 - 9 6.8 21.4 0.91 10.0 14.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Actin PF00022.19 KER22423.1 - 4.2e-151 503.2 0.0 1.3e-150 501.5 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER22424.1 - 2.7e-151 503.8 0.0 8.7e-151 502.1 0.0 1.6 1 1 0 1 1 1 1 Actin Ig_3 PF13927.6 KER22425.1 - 3.3e-20 72.5 5.6 8.2e-08 32.8 1.6 6.9 7 0 0 7 7 7 3 Immunoglobulin domain I-set PF07679.16 KER22425.1 - 4.1e-10 39.6 0.0 0.045 13.8 0.0 5.2 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KER22425.1 - 6.5e-10 39.2 0.9 0.0044 17.3 0.1 6.1 5 1 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 KER22425.1 - 1.8e-08 34.4 3.9 0.21 11.8 0.0 5.8 5 1 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 KER22425.1 - 1.5e-07 31.6 7.4 0.53 10.5 0.0 7.7 6 3 1 7 7 7 2 Immunoglobulin V-set domain fn3 PF00041.21 KER22425.1 - 1.6e-06 28.3 0.5 3.8 7.9 0.0 5.5 5 0 0 5 5 5 1 Fibronectin type III domain Ig_5 PF16681.5 KER22425.1 - 0.0055 17.1 0.0 3.6 8.1 0.0 3.2 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KER22425.1 - 0.0063 16.8 0.0 18 5.7 0.0 3.5 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KER22425.1 - 0.028 14.0 0.0 16 5.1 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KER22425.1 - 0.19 12.3 1.1 1.2 9.8 0.0 2.8 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Pkinase PF00069.25 KER22427.1 - 7.2e-54 182.9 0.2 3.7e-41 141.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER22427.1 - 2.9e-34 118.5 0.1 5.7e-25 88.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER22427.1 - 2.7e-09 36.3 0.2 8.2e-09 34.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KER22427.1 - 1.5e-06 28.0 0.5 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KER22427.1 - 0.0002 21.4 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER22427.1 - 0.014 14.4 1.1 0.018 14.0 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain MHC2-interact PF09307.10 KER22428.1 - 0.1 12.6 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 CLIP, MHC2 interacting Complex1_49kDa PF00346.19 KER22429.1 - 2.2e-113 377.9 0.0 3.5e-113 377.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit XRCC4 PF06632.12 KER22429.1 - 0.023 13.6 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Hydantoinase_B PF02538.14 KER22429.1 - 0.061 11.7 0.0 0.089 11.2 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase NiFeSe_Hases PF00374.19 KER22429.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase SLED PF12140.8 KER22429.1 - 0.16 12.5 1.4 32 5.1 0.0 3.0 3 0 0 3 3 3 0 SLED domain Tetraspanin PF00335.20 KER22430.1 - 3.5e-26 92.3 11.7 4.7e-26 91.9 11.7 1.1 1 0 0 1 1 1 1 Tetraspanin family PDR_CDR PF06422.12 KER22430.1 - 0.25 11.2 1.4 4.4 7.3 0.3 2.6 2 0 0 2 2 2 0 CDR ABC transporter Saf_2TM PF18303.1 KER22430.1 - 6.1 6.4 9.5 0.15 11.6 0.5 2.8 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain PALP PF00291.25 KER22431.1 - 2.3e-61 207.8 0.0 3.5e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.27 KER22431.1 - 2.5e-21 76.2 0.0 5.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KER22431.1 - 2.1e-05 24.2 0.1 5.4e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER22431.1 - 0.00021 21.1 0.0 0.00075 19.3 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MaoC_dehydratas PF01575.19 KER22432.1 - 0.028 14.0 0.0 16 5.1 0.0 3.1 2 1 1 3 3 3 0 MaoC like domain F-box_4 PF15966.5 KER22433.1 - 7.5e-27 93.5 0.6 2.5e-26 91.8 0.1 1.9 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KER22433.1 - 2.2e-22 79.4 34.5 1.1e-20 73.9 23.2 3.9 4 1 0 4 4 4 2 TRAF-like zinc-finger zf-TRAF PF02176.18 KER22433.1 - 7e-07 29.8 10.1 7e-07 29.8 10.1 5.2 3 2 2 5 5 5 1 TRAF-type zinc finger zf-U11-48K PF05253.12 KER22433.1 - 4 7.5 11.4 2.6 8.1 0.4 4.4 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger T2SS-T3SS_pil_N PF13629.6 KER22434.1 - 0.049 13.4 0.0 1.6 8.5 0.0 3.6 3 0 0 3 3 3 0 Pilus formation protein N terminal region RrnaAD PF00398.20 KER22435.1 - 0.04 13.0 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_C13 PF01650.18 KER22436.1 - 4.6e-80 268.8 1.0 6.3e-80 268.4 1.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER22436.1 - 1.5e-05 25.1 0.1 2.7e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Caspase domain Peptidase_C13 PF01650.18 KER22437.1 - 2.6e-63 214.0 1.4 1.2e-42 146.2 0.3 2.0 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C25 PF01364.18 KER22437.1 - 0.0036 16.5 0.0 0.0049 16.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family C25 Peptidase_C14 PF00656.22 KER22437.1 - 0.0068 16.4 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DREV PF05219.12 KER22437.1 - 0.037 13.1 0.1 0.068 12.3 0.0 1.4 2 0 0 2 2 2 0 DREV methyltransferase EF-hand_7 PF13499.6 KER22438.1 - 1.1e-23 83.5 3.5 4.3e-16 59.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER22438.1 - 7.2e-22 75.3 9.2 1.2e-06 27.6 0.5 4.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER22438.1 - 2.6e-20 70.5 0.5 2.3e-05 24.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KER22438.1 - 2.3e-17 62.5 2.6 1.4e-07 31.2 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER22438.1 - 8.4e-17 59.8 4.2 1.6e-06 27.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KER22438.1 - 8.6e-06 25.6 0.8 0.19 11.7 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER22438.1 - 0.00055 20.2 0.3 0.47 10.8 0.0 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER22438.1 - 0.0021 18.3 0.0 0.0089 16.3 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 KER22438.1 - 0.0023 17.8 0.6 2.3 8.2 0.0 3.1 3 1 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KER22438.1 - 0.019 15.2 0.3 1.6 9.0 0.2 2.8 1 1 1 2 2 2 0 Dockerin type I domain MecA_N PF05223.11 KER22438.1 - 0.14 12.5 0.1 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain SDA1 PF05285.12 KER22439.1 - 0.006 16.1 27.5 0.0064 16.0 27.5 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 KER22439.1 - 0.021 14.2 23.0 0.023 14.1 23.0 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KER22439.1 - 0.59 8.3 30.8 0.71 8.0 30.8 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 KER22441.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CD36 PF01130.21 KER22442.1 - 1.9e-50 171.8 0.0 7.8e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 CD36 family CD36 PF01130.21 KER22443.1 - 7.2e-20 71.0 1.0 2e-17 62.9 1.0 2.0 1 1 0 1 1 1 1 CD36 family CD36 PF01130.21 KER22445.1 - 1.4e-18 66.7 0.8 3e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 CD36 family FANCI_HD1 PF14679.6 KER22446.1 - 0.084 12.8 0.5 0.17 11.9 0.5 1.5 1 1 0 1 1 1 0 FANCI helical domain 1 Ost4 PF10215.9 KER22446.1 - 0.26 11.1 4.3 0.46 10.4 4.3 1.3 1 0 0 1 1 1 0 Oligosaccaryltransferase UQ_con PF00179.26 KER22447.1 - 1.8e-53 180.0 0.0 2e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER22447.1 - 0.00037 20.2 0.0 0.00043 20.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER22447.1 - 0.0048 17.2 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KER22447.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DLIC PF05783.11 KER22451.1 - 7.8e-81 272.3 0.3 5.6e-44 150.7 0.1 3.1 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KER22451.1 - 0.0011 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER22451.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras family CAP_GLY PF01302.25 KER22452.1 - 4e-97 318.2 10.5 1.5e-24 85.7 0.1 4.7 4 0 0 4 4 4 4 CAP-Gly domain PIG-U PF06728.13 KER22452.1 - 8.4e-52 176.5 21.8 1.2e-45 156.2 20.1 2.1 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U Ank PF00023.30 KER22452.1 - 2.7e-08 33.9 0.3 0.023 15.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KER22452.1 - 3.5e-08 33.9 0.0 3.9e-06 27.4 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER22452.1 - 1.8e-06 28.4 0.1 0.0005 20.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER22452.1 - 2.4e-05 24.3 0.4 0.42 11.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KER22452.1 - 0.00087 19.5 0.8 0.096 13.0 0.0 3.2 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Dynein_light PF01221.18 KER22455.1 - 3.1e-22 78.7 0.0 4.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Patched PF02460.18 KER22456.1 - 4.2e-66 223.6 12.2 7.1e-41 140.2 0.0 2.3 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 KER22456.1 - 1.1e-48 165.9 2.5 1.7e-48 165.3 2.5 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 KER22456.1 - 2.1e-42 144.6 7.8 2.6e-24 85.8 1.5 4.2 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KER22456.1 - 0.0044 16.9 3.6 0.011 15.6 3.6 1.6 1 0 0 1 1 1 1 Folate receptor family ArAE_2_N PF10337.9 KER22456.1 - 2.6 7.0 7.3 5.1 6.0 7.3 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4337 PF14235.6 KER22456.1 - 5 7.2 7.2 25 5.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CDC45 PF02724.14 KER22457.1 - 0.13 10.5 4.5 0.15 10.4 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER22457.1 - 0.42 8.8 9.2 0.43 8.7 9.2 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 KER22457.1 - 0.76 9.8 7.5 0.73 9.9 7.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 KER22457.1 - 1.3 8.4 11.3 1.4 8.2 11.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER22457.1 - 2.2 7.5 7.0 2 7.7 7.0 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 KER22457.1 - 5.6 6.2 18.7 8.5 5.6 18.7 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KER22457.1 - 9.6 6.0 9.3 11 5.8 9.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tetraspanin PF00335.20 KER22460.1 - 3.9e-23 82.4 9.0 3.9e-23 82.4 9.0 1.4 2 0 0 2 2 2 1 Tetraspanin family FtsX PF02687.21 KER22460.1 - 2.1 8.8 15.9 4.7 7.8 7.1 2.4 2 0 0 2 2 2 0 FtsX-like permease family SLATT_4 PF18186.1 KER22460.1 - 2.3 7.8 3.5 2.5 7.7 0.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Yip1 PF04893.17 KER22460.1 - 9.9 5.8 21.1 1.1 9.0 4.5 2.2 1 1 1 2 2 2 0 Yip1 domain P34-Arc PF04045.14 KER22462.1 - 6.2e-101 337.1 1.7 4e-64 216.6 1.7 2.0 2 0 0 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc DUF819 PF05684.12 KER22462.1 - 0.081 12.0 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) P34-Arc PF04045.14 KER22464.1 - 4e-91 305.0 0.1 4.6e-91 304.8 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc UQ_con PF00179.26 KER22465.1 - 1.6e-18 66.7 0.0 1.8e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ras PF00071.22 KER22466.1 - 8.1e-21 74.3 0.0 1.2e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Ras family DnaJ PF00226.31 KER22466.1 - 3.2e-15 56.0 0.0 5.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Roc PF08477.13 KER22466.1 - 1.9e-06 28.1 0.0 5.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER22466.1 - 0.00022 20.8 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2277 PF10041.9 KER22466.1 - 0.087 13.2 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ORMDL PF04061.14 KER22467.1 - 1.7e-50 170.4 1.9 3e-50 169.6 1.9 1.4 1 0 0 1 1 1 1 ORMDL family tRNA-synt_2 PF00152.20 KER22470.1 - 6.7e-91 304.6 0.0 9.4e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KER22470.1 - 3.6e-12 46.1 0.0 6.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 KER22470.1 - 0.03 13.9 0.4 0.066 12.8 0.0 1.7 2 0 0 2 2 2 0 tRNA_anti-like Asp PF00026.23 KER22473.1 - 3e-26 92.6 0.1 3.3e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22473.1 - 0.0019 18.0 0.1 0.0052 16.6 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER22474.1 - 6.7e-14 52.0 0.0 1.5e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22474.1 - 0.17 11.6 0.0 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Asp PF00026.23 KER22475.1 - 3.9e-22 79.1 0.0 8.4e-22 78.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22475.1 - 1.3e-05 25.1 0.0 0.00014 21.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KER22475.1 - 0.12 13.0 0.0 34 5.1 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KER22476.1 - 1.3e-12 47.8 0.1 6.6e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.23 KER22477.1 - 8.9e-17 61.5 0.0 9.8e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22477.1 - 0.00024 20.9 0.0 0.00032 20.5 0.0 1.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER22478.1 - 1.8e-53 182.0 0.0 7.7e-27 94.5 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22478.1 - 0.00014 21.7 0.1 0.19 11.5 0.0 3.8 2 2 0 3 3 3 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KER22478.1 - 0.00027 21.2 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal NblA PF04485.12 KER22478.1 - 0.08 13.4 0.7 0.17 12.3 0.7 1.5 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Asp PF00026.23 KER22479.1 - 1.2e-08 34.8 0.0 1.3e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER22479.1 - 0.14 12.3 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.23 KER22480.1 - 4.4e-21 75.6 0.0 1.2e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22480.1 - 3e-05 23.8 0.0 0.0066 16.2 0.0 3.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER22481.1 - 1.5e-20 73.9 0.4 4.7e-20 72.2 0.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER22481.1 - 0.00013 21.8 0.4 0.001 18.9 0.4 2.5 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER22482.1 - 8e-35 120.8 0.9 2.4e-16 60.1 0.0 4.0 2 1 2 4 4 4 4 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER22482.1 - 6.2e-05 23.3 0.1 2.6 8.3 0.0 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER22482.1 - 0.0027 18.3 0.0 1.4 9.6 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KER22482.1 - 0.036 14.6 0.0 9 6.9 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease NblA PF04485.12 KER22482.1 - 0.069 13.6 0.7 0.16 12.4 0.7 1.5 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA Peptidase_S8 PF00082.22 KER22483.1 - 7.7e-47 160.0 1.7 1e-46 159.6 1.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KER22483.1 - 3.4e-23 81.5 0.1 6.7e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KER22483.1 - 9.1e-20 71.2 0.3 1.7e-19 70.3 0.3 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Cadherin_3 PF16184.5 KER22484.1 - 2.6e-41 140.1 11.9 2.1e-06 27.7 0.1 10.8 8 2 0 8 8 8 8 Cadherin-like DUF5641 PF18701.1 KER22484.1 - 4.2e-26 90.9 0.1 1e-25 89.7 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Integrase_H2C2 PF17921.1 KER22484.1 - 3.3e-09 36.7 2.4 4.6e-09 36.3 0.8 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KER22484.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1759 PF03564.15 KER22484.1 - 0.00036 20.5 0.0 0.00098 19.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) zf-H2C2 PF09337.10 KER22484.1 - 0.019 15.2 0.8 0.089 13.0 0.8 2.3 1 0 0 1 1 1 0 H2C2 zinc finger Vg_Tdu PF07545.14 KER22485.1 - 1.7 8.5 9.0 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Vestigial/Tondu family DNA_pol_phi PF04931.13 KER22486.1 - 0.14 10.2 35.6 0.15 10.2 35.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 KER22486.1 - 0.43 9.5 1.8 0.43 9.5 1.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 KER22486.1 - 0.51 9.6 36.7 0.62 9.3 36.7 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.10 KER22486.1 - 0.65 10.3 6.2 0.74 10.1 6.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.8 KER22486.1 - 0.67 8.7 2.2 0.72 8.6 2.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTPRCAP PF15713.5 KER22486.1 - 0.93 9.8 14.4 1.4 9.2 14.4 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 KER22486.1 - 1.2 8.5 21.4 1.3 8.4 21.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RPA43_OB PF17875.1 KER22486.1 - 1.7 9.3 4.2 2.6 8.7 4.2 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Nop14 PF04147.12 KER22486.1 - 1.8 6.7 26.8 2 6.6 26.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2428 PF10350.9 KER22486.1 - 2.3 7.4 3.0 2.1 7.5 3.0 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) RPN2_C PF18004.1 KER22486.1 - 2.9 7.8 6.5 3.3 7.6 6.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 KER22486.1 - 2.9 7.6 11.8 3.5 7.3 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 KER22486.1 - 3.7 5.7 22.0 4 5.6 22.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KER22486.1 - 5 5.5 22.7 5.6 5.3 22.7 1.0 1 0 0 1 1 1 0 Mpp10 protein IFT57 PF10498.9 KER22486.1 - 6.3 5.6 13.9 7.5 5.4 13.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop53 PF07767.11 KER22486.1 - 8.6 5.6 12.6 9.6 5.5 12.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PH PF00169.29 KER22487.1 - 3.1e-19 69.4 0.3 3.9e-10 40.2 0.1 2.4 2 0 0 2 2 2 2 PH domain ArfGap PF01412.18 KER22487.1 - 2.3e-18 66.4 0.0 3.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_11 PF15413.6 KER22487.1 - 7.3e-08 32.8 0.6 9.2e-05 22.8 0.8 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 KER22487.1 - 0.00039 20.6 0.2 0.29 11.4 0.0 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KER22487.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region TatD_DNase PF01026.21 KER22489.1 - 3.3e-20 72.5 0.0 1.9e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 TatD related DNase DUF2315 PF10231.9 KER22490.1 - 4.6e-22 78.4 0.7 8e-22 77.6 0.7 1.4 1 1 0 1 1 1 1 Apoptogenic protein 1 L_HMGIC_fpl PF10242.9 KER22491.1 - 2.1e-22 80.2 9.9 3.6e-22 79.5 9.9 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Plectin PF00681.20 KER22492.1 - 0.04 13.8 0.0 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 Plectin repeat RNase_PH PF01138.21 KER22494.1 - 9.3e-06 26.2 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Med19 PF10278.9 KER22495.1 - 7e-36 123.8 7.6 7.9e-35 120.4 0.0 2.6 3 0 0 3 3 3 2 Mediator of RNA pol II transcription subunit 19 Phage_Gp17 PF17549.2 KER22497.1 - 0.098 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Gene Product 17 NOD PF06816.13 KER22498.1 - 0.091 12.4 0.1 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 NOTCH protein fn3 PF00041.21 KER22499.1 - 0.025 14.9 8.0 0.058 13.7 0.2 4.3 4 1 0 4 4 4 0 Fibronectin type III domain DUF4041 PF13250.6 KER22499.1 - 0.087 12.7 0.3 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Thioredoxin_13 PF18401.1 KER22499.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Y_phosphatase PF00102.27 KER22500.1 - 3.4e-43 147.9 0.0 3.9e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KER22500.1 - 0.00051 19.9 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER22500.1 - 0.019 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KER22500.1 - 0.022 14.9 0.0 0.053 13.6 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate RSB_motif PF16294.5 KER22501.1 - 0.11 12.7 4.4 0.29 11.4 4.4 1.7 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif DUF1631 PF07793.11 KER22501.1 - 0.14 10.5 1.7 1.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) RR_TM4-6 PF06459.12 KER22501.1 - 9.1 6.0 7.9 15 5.3 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hist_deacetyl PF00850.19 KER22504.1 - 1.2e-76 258.2 0.8 1.5e-76 257.8 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain DUF981 PF06168.11 KER22505.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2892 PF11127.8 KER22505.1 - 4.9 7.3 7.0 11 6.2 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) RRM_1 PF00076.22 KER22509.1 - 5.4e-14 51.8 0.0 0.00072 19.3 0.0 4.2 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER22509.1 - 5.5e-06 26.4 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif GTF2I PF02946.14 KER22509.1 - 0.0095 16.0 0.0 4.7 7.4 0.0 2.6 3 0 0 3 3 3 2 GTF2I-like repeat UPF0239 PF06783.11 KER22509.1 - 6.8 7.0 6.7 32 4.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) KH_8 PF17903.1 KER22510.1 - 0.00039 20.5 0.1 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KER22510.1 - 0.02 14.7 1.6 0.037 13.8 1.6 1.4 1 0 0 1 1 1 0 KH domain SSF PF00474.17 KER22511.1 - 1.9e-19 69.8 19.9 7.5e-19 67.9 19.9 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family DZR PF12773.7 KER22513.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon rve PF00665.26 KER22514.1 - 1.4e-06 28.5 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 KER22514.1 - 2.6e-05 24.0 0.2 5.2e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 KER22514.1 - 0.0015 18.3 0.0 0.0054 16.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KER22514.1 - 0.004 17.7 0.0 0.0097 16.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4129 PF13559.6 KER22514.1 - 0.026 14.8 0.8 0.026 14.8 0.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) WD40 PF00400.32 KER22515.1 - 2e-22 79.0 9.8 2.4e-06 28.2 0.1 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22515.1 - 2.2e-05 24.7 7.1 0.43 10.9 0.0 4.9 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER22515.1 - 0.0082 15.1 0.0 0.056 12.4 0.0 2.1 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KER22515.1 - 0.028 14.3 0.1 4.6 7.1 0.0 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DNA_RNApol_7kD PF03604.13 KER22517.1 - 7.6e-15 54.3 6.6 9.6e-15 54.0 6.6 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KER22517.1 - 0.03 14.3 0.3 0.031 14.3 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 KER22517.1 - 0.044 14.5 0.3 0.065 13.9 0.3 1.3 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KER22517.1 - 0.046 13.8 0.3 0.058 13.4 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.18 KER22517.1 - 0.071 13.0 1.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_10 PF10058.9 KER22517.1 - 0.23 11.2 2.7 2.2 8.1 2.7 2.0 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF1992 PF09350.10 KER22518.1 - 6.8e-20 71.0 0.1 1.9e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DnaJ PF00226.31 KER22518.1 - 2.2e-06 27.7 0.0 6.1e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain FIVAR PF07554.13 KER22518.1 - 1.2 10.0 4.7 14 6.6 0.8 2.5 2 0 0 2 2 2 0 FIVAR domain SPRY PF00622.28 KER22519.1 - 1.5e-16 60.6 0.5 4.5e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 KER22519.1 - 4.6e-16 59.0 0.0 1.7e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KER22519.1 - 0.00019 21.2 0.0 0.00054 19.8 0.0 1.8 2 0 0 2 2 2 1 LisH NOA36 PF06524.12 KER22519.1 - 0.5 9.6 24.7 0.71 9.1 16.6 2.2 2 0 0 2 2 2 0 NOA36 protein I-set PF07679.16 KER22522.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER22522.1 - 6.8e-14 52.2 0.0 2.9e-13 50.2 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER22522.1 - 3.8e-10 40.0 0.0 1.3e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER22522.1 - 2.4e-08 34.0 0.1 8.9e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KER22522.1 - 0.00034 20.7 0.0 0.0038 17.4 0.0 2.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER22522.1 - 0.014 15.4 0.0 0.059 13.5 0.0 2.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 KER22522.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain TPR_12 PF13424.6 KER22523.1 - 2.9e-05 24.3 0.1 0.00048 20.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER22523.1 - 4.5e-05 23.2 0.0 0.088 12.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DivIC PF04977.15 KER22523.1 - 0.058 13.2 1.0 0.13 12.1 1.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Spore_III_AB PF09548.10 KER22523.1 - 0.059 13.5 0.3 0.19 11.9 0.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) BMP2K_C PF15282.6 KER22523.1 - 0.11 12.3 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus Shugoshin_N PF07558.11 KER22524.1 - 0.057 13.3 16.4 0.14 12.0 0.3 4.6 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region HTH_IclR PF09339.10 KER22524.1 - 0.12 12.2 1.4 3.9 7.4 0.2 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF2935 PF11155.8 KER22524.1 - 2.7 8.4 9.7 1.5 9.2 1.2 4.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) FixH PF05751.11 KER22524.1 - 3.7 7.6 4.9 3 7.8 0.2 2.7 1 1 1 2 2 2 0 FixH HORMA PF02301.18 KER22526.1 - 1.6e-21 76.9 0.7 2.6e-21 76.2 0.7 1.3 1 1 0 1 1 1 1 HORMA domain Ribonuc_red_sm PF00268.21 KER22528.1 - 5.6e-117 390.2 0.3 6.6e-117 389.9 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 KER22528.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4744 PF15918.5 KER22528.1 - 0.15 12.9 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) TPR_12 PF13424.6 KER22529.1 - 6.2e-10 39.2 2.0 5.6e-08 33.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER22529.1 - 3.1e-08 32.9 0.8 3.1e-08 32.9 0.8 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 KER22529.1 - 6.9e-06 25.8 0.1 1.7 9.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER22529.1 - 1.8e-05 24.4 0.8 0.00021 21.1 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER22529.1 - 0.00039 20.4 0.2 15 6.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER22529.1 - 0.0012 18.6 0.2 5.8 6.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PikAIV_N PF18605.1 KER22529.1 - 0.0056 16.2 2.2 0.0067 16.0 0.7 2.0 2 0 0 2 2 2 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TPR_MalT PF17874.1 KER22529.1 - 0.0089 15.4 0.7 1.4 8.3 0.2 2.7 2 1 1 3 3 3 1 MalT-like TPR region Tup_N PF08581.10 KER22529.1 - 0.025 14.9 5.5 0.095 13.0 0.2 3.0 2 0 0 2 2 2 0 Tup N-terminal Med9 PF07544.13 KER22529.1 - 0.071 13.2 1.9 4.7 7.4 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_11 PF13414.6 KER22529.1 - 0.082 12.6 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat RPW8 PF05659.11 KER22529.1 - 0.22 11.2 1.6 0.97 9.1 0.0 2.7 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Pkinase PF00069.25 KER22530.1 - 6.1e-65 219.2 0.0 7.3e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22530.1 - 9.9e-32 110.2 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER22530.1 - 5.5e-06 25.9 0.1 1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RRM_1 PF00076.22 KER22535.1 - 2.9e-18 65.5 0.0 4.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KER22535.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HEPN_AbiU2 PF18734.1 KER22536.1 - 0.13 11.7 0.7 0.3 10.6 0.7 1.5 1 0 0 1 1 1 0 AbiU2 AA_permease_N PF08403.10 KER22538.1 - 0.076 12.5 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Amino acid permease N-terminal TCR PF03638.15 KER22541.1 - 9.6e-24 83.4 55.0 4.7e-12 46.0 23.1 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KER22541.1 - 0.0045 17.1 45.9 0.015 15.4 18.8 2.6 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 TFIIE_alpha PF02002.17 KER22542.1 - 3.3e-19 68.7 4.4 5.4e-19 68.0 4.4 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit DUF4026 PF13218.6 KER22542.1 - 0.065 12.2 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) HTH_Mga PF08280.11 KER22542.1 - 0.065 13.3 0.5 0.15 12.1 0.5 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Mito_morph_reg PF14972.6 KER22543.1 - 1.3e-38 132.2 0.8 2.2e-31 108.6 0.2 2.7 2 1 0 2 2 2 2 Mitochondrial morphogenesis regulator CSG2 PF16965.5 KER22543.1 - 0.14 11.1 0.7 0.21 10.5 0.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator LLGL PF08366.13 KER22545.1 - 1.5e-17 63.8 0.0 9.5e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 LLGL2 ANAPC4_WD40 PF12894.7 KER22545.1 - 0.14 12.5 0.0 1.8 8.9 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER22545.1 - 5.3 8.1 8.1 15 6.7 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat PDEase_I PF00233.19 KER22547.1 - 1.9e-67 227.5 0.4 3.4e-67 226.6 0.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KER22547.1 - 1e-14 55.3 0.0 2.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KER22547.1 - 1.7e-12 47.8 0.0 2.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KER22547.1 - 7.2e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain RMI1_N PF08585.12 KER22547.1 - 0.2 11.4 0.6 1.9 8.2 0.7 2.3 2 1 0 2 2 2 0 RecQ mediated genome instability protein HMG-CoA_red PF00368.18 KER22550.1 - 1.7e-120 402.4 0.0 2.2e-120 402.0 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF3180 PF11377.8 KER22550.1 - 2.3 8.4 8.7 0.79 9.9 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) TraO PF10626.9 KER22551.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Conjugative transposon protein TraO SPT_ssu-like PF11779.8 KER22552.1 - 0.051 13.2 2.5 0.21 11.3 0.2 2.4 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like Vta1 PF04652.16 KER22553.1 - 5.4e-36 123.7 2.5 5.4e-36 123.7 2.5 1.4 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KER22553.1 - 1.5e-09 37.4 0.7 1.5e-09 37.4 0.7 2.6 3 0 0 3 3 3 1 Vta1 C-terminal domain SRA1 PF07304.11 KER22553.1 - 0.17 11.7 0.6 0.34 10.7 0.6 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Peptidase_M41 PF01434.18 KER22555.1 - 8.8e-54 182.3 0.2 2.2e-53 181.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KER22555.1 - 2.8e-45 154.0 0.2 8.6e-45 152.4 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER22555.1 - 4.4e-13 48.8 0.1 1.1e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KER22555.1 - 2.5e-08 34.3 0.0 2.6e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular Asp_protease_2 PF13650.6 KER22555.1 - 8.9e-08 32.7 0.1 0.0051 17.4 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KER22555.1 - 1.4e-06 28.7 0.0 0.0099 16.4 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Tn7_Tnp_TnsA_C PF08721.11 KER22555.1 - 0.00075 20.1 0.1 2.8 8.7 0.0 2.8 2 0 0 2 2 2 2 TnsA endonuclease C terminal AAA_5 PF07728.14 KER22555.1 - 0.00098 19.1 0.1 0.01 15.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RVT_1 PF00078.27 KER22555.1 - 0.0031 17.1 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_22 PF13401.6 KER22555.1 - 0.0069 16.7 1.0 0.83 9.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 KER22555.1 - 0.0093 15.2 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KER22555.1 - 0.012 15.7 0.1 0.064 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KER22555.1 - 0.037 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KER22555.1 - 0.13 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_L34e PF01199.18 KER22556.1 - 4.2e-27 94.3 4.2 7e-27 93.6 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Sod_Fe_N PF00081.22 KER22557.1 - 1.3e-15 57.6 2.7 2.1e-15 57.0 2.7 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 KER22557.1 - 6.8e-12 45.4 0.1 2e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Adaptin_N PF01602.20 KER22557.1 - 0.22 10.0 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Proteasome PF00227.26 KER22558.1 - 1.4e-43 148.6 2.9 1.8e-43 148.2 0.9 2.1 2 0 0 2 2 2 1 Proteasome subunit Cullin PF00888.22 KER22558.1 - 3.4e-24 85.4 0.9 6.1e-24 84.6 0.9 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KER22558.1 - 8.2e-21 74.3 0.1 2.5e-20 72.7 0.1 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Metallophos PF00149.28 KER22558.1 - 2.4e-07 31.5 0.0 6.9e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3752 PF12572.8 KER22558.1 - 0.0043 17.6 13.5 0.0043 17.6 13.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) HTH_IclR PF09339.10 KER22558.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain REV PF00424.18 KER22559.1 - 0.038 14.0 1.0 0.043 13.8 1.0 1.2 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF3176 PF11374.8 KER22559.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DUF4849 PF16141.5 KER22560.1 - 0.19 11.0 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 SPRY PF00622.28 KER22562.1 - 2.7e-31 108.2 0.6 3.1e-18 66.0 0.1 2.6 2 0 0 2 2 2 2 SPRY domain FERM_N PF09379.10 KER22562.1 - 1.5e-17 63.3 0.0 6.4e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 KER22562.1 - 5.8e-17 61.9 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 KER22562.1 - 1.6e-14 54.3 0.0 2.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 FERM central domain SSF PF00474.17 KER22564.1 - 3.2e-30 105.3 16.8 6.1e-30 104.4 10.3 2.2 2 0 0 2 2 2 2 Sodium:solute symporter family NapE PF06796.11 KER22564.1 - 0.083 12.4 3.4 0.1 12.2 0.0 3.0 4 0 0 4 4 4 0 Periplasmic nitrate reductase protein NapE DUF5532 PF17673.1 KER22565.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5532) SSF PF00474.17 KER22566.1 - 9.9e-06 24.7 0.8 1.3e-05 24.3 0.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 KER22567.1 - 2.9e-46 158.2 28.1 5.5e-46 157.2 28.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Tenui_PVC2 PF06656.11 KER22567.1 - 0.025 12.5 0.9 0.037 11.9 0.9 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Ins134_P3_kin PF05770.11 KER22568.1 - 5.7e-43 146.8 0.0 7.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain SH3_10 PF17902.1 KER22569.1 - 8.3e-05 22.6 0.0 0.65 10.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain DUF2408 PF10303.9 KER22569.1 - 0.016 15.7 0.1 0.063 13.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 KER22569.1 - 6.3 7.3 5.9 6.7 7.2 0.1 3.5 3 1 1 4 4 4 0 Snapin/Pallidin Ins134_P3_kin PF05770.11 KER22570.1 - 0.0021 17.6 0.0 0.034 13.7 0.0 2.0 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain ATG16 PF08614.11 KER22571.1 - 7.4e-20 72.0 20.9 7.9e-20 71.9 19.6 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 KER22571.1 - 4e-16 59.1 3.7 0.012 16.4 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat LSM PF01423.22 KER22571.1 - 3.3e-12 45.9 0.0 8.2e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 LSM domain DUF4763 PF15960.5 KER22571.1 - 0.0024 17.2 21.5 0.01 15.1 5.4 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4763) CALCOCO1 PF07888.11 KER22571.1 - 0.0028 16.6 12.3 0.0028 16.6 12.3 2.1 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Nup160 PF11715.8 KER22571.1 - 0.0033 16.1 5.1 0.48 9.0 0.2 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cnn_1N PF07989.11 KER22571.1 - 0.006 16.7 3.5 0.006 16.7 3.5 3.4 1 1 3 4 4 4 1 Centrosomin N-terminal motif 1 Myosin_tail_1 PF01576.19 KER22571.1 - 0.016 13.1 25.6 0.052 11.4 9.0 2.1 1 1 1 2 2 2 0 Myosin tail TNF PF00229.18 KER22571.1 - 0.035 14.1 0.3 0.093 12.7 0.3 1.7 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family CENP-F_leu_zip PF10473.9 KER22571.1 - 0.081 12.9 29.6 1.3 9.0 1.1 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KER22571.1 - 0.087 12.6 20.6 0.15 11.8 13.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 KER22571.1 - 0.2 12.1 31.4 0.25 11.8 6.5 4.9 2 2 3 5 5 5 0 Cell division protein ZapB DUF1664 PF07889.12 KER22571.1 - 0.48 10.5 13.3 2.1 8.4 2.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KER22571.1 - 0.67 8.8 25.4 0.041 12.8 17.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KER22571.1 - 0.76 9.6 19.8 2.5 8.0 0.2 4.7 1 1 3 4 4 4 0 Septum formation initiator MbeD_MobD PF04899.12 KER22571.1 - 0.78 9.9 5.0 12 6.1 0.1 3.9 2 1 0 4 4 4 0 MbeD/MobD like SidE PF12252.8 KER22571.1 - 1.1 6.7 16.8 0.47 7.9 10.9 2.0 1 1 1 2 2 2 0 Dot/Icm substrate protein Bacillus_HBL PF05791.11 KER22571.1 - 1.4 8.7 12.1 0.093 12.6 2.0 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-H PF05837.12 KER22571.1 - 1.8 9.0 23.3 20 5.6 13.9 3.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) LOH1CR12 PF10158.9 KER22571.1 - 2.2 8.3 8.2 3 7.9 1.6 2.8 1 1 2 3 3 3 0 Tumour suppressor protein DUF3450 PF11932.8 KER22571.1 - 2.3 7.5 17.2 0.24 10.7 4.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 KER22571.1 - 4.2 7.7 7.8 2.3 8.5 0.8 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KER22571.1 - 5.5 7.5 10.0 11 6.6 0.5 3.1 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 KER22571.1 - 5.6 7.2 24.3 2 8.6 10.1 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 KER22571.1 - 6.6 7.2 17.2 20 5.7 0.5 4.4 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 KER22571.1 - 6.9 6.6 14.8 2.3 8.2 0.4 3.8 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor MscS_porin PF12795.7 KER22571.1 - 7.9 5.9 21.6 12 5.4 21.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain bZIP_1 PF00170.21 KER22571.1 - 9.7 6.4 26.9 3.8 7.7 3.4 4.7 4 0 0 4 4 4 0 bZIP transcription factor Ins134_P3_kin PF05770.11 KER22572.1 - 1.6e-37 129.0 0.1 3.9e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain RasGEF PF00617.19 KER22574.1 - 3.2e-27 95.9 0.0 1.1e-26 94.2 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KER22574.1 - 0.0099 16.1 4.0 0.11 12.7 0.1 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif T-box PF00907.22 KER22575.1 - 1.2e-79 266.9 0.7 1.2e-79 266.9 0.7 2.1 2 0 0 2 2 2 1 T-box GD_AH_C PF04295.13 KER22576.1 - 0.006 15.4 0.0 0.0069 15.2 0.0 1.1 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus Nuc_sug_transp PF04142.15 KER22577.1 - 5.7e-05 22.4 1.0 0.00012 21.4 1.0 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KER22577.1 - 6.8e-05 23.1 17.4 0.0015 18.7 4.3 3.0 2 2 0 2 2 2 2 EamA-like transporter family Ras PF00071.22 KER22579.1 - 4.2e-50 169.5 0.0 5.3e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER22579.1 - 5e-31 107.4 0.0 1.1e-30 106.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER22579.1 - 1e-10 41.3 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER22579.1 - 0.00047 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER22579.1 - 0.00075 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KER22579.1 - 0.0015 17.8 1.8 0.7 9.0 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 KER22579.1 - 0.0015 18.9 0.1 0.013 15.9 0.1 2.2 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 KER22579.1 - 0.0052 16.3 0.3 0.018 14.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER22579.1 - 0.021 14.8 0.1 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KER22579.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ArgoMid PF16487.5 KER22579.1 - 0.04 14.2 0.1 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute AAA_7 PF12775.7 KER22579.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KER22579.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KER22579.1 - 0.058 13.3 0.3 0.088 12.7 0.3 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KER22579.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KER22579.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 KER22579.1 - 0.15 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP-sulfurylase PF01747.17 KER22580.1 - 3.2e-65 219.6 0.0 4.6e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KER22580.1 - 3.8e-65 218.6 0.0 6.1e-65 217.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KER22580.1 - 6.9e-44 149.3 0.0 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CbiA PF01656.23 KER22580.1 - 0.00052 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KER22580.1 - 0.0031 17.7 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KER22580.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FliG_M PF14841.6 KER22581.1 - 0.045 14.0 0.2 0.045 14.0 0.2 2.4 3 0 0 3 3 3 0 FliG middle domain HSBP1 PF06825.12 KER22581.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Curto_V3 PF07436.11 KER22581.1 - 0.12 12.7 0.2 0.39 11.1 0.1 1.9 2 0 0 2 2 2 0 Curtovirus V3 protein Pkinase_Tyr PF07714.17 KER22584.1 - 4.1e-11 42.7 0.0 8.4e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER22584.1 - 2.6e-06 27.0 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Tox-ART-HYE1 PF15634.6 KER22586.1 - 0.042 13.1 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase FAM124 PF15067.6 KER22587.1 - 0.039 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 FAM124 family DUF4026 PF13218.6 KER22587.1 - 0.043 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) zf-met PF12874.7 KER22588.1 - 0.00027 21.2 1.7 0.019 15.4 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER22588.1 - 0.0062 16.8 1.4 0.43 10.9 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding TLE_N PF03920.15 KER22589.1 - 2e-49 167.0 16.5 8.2e-49 165.0 12.9 2.5 2 1 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KER22589.1 - 2.2e-13 50.4 16.0 0.036 14.9 0.2 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22589.1 - 0.00023 21.4 0.2 0.0065 16.7 0.0 3.3 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 KER22589.1 - 0.11 12.8 0.3 0.21 11.8 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Tetraspanin PF00335.20 KER22590.1 - 2.6e-19 69.8 10.4 3.4e-19 69.5 10.4 1.1 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.23 KER22590.1 - 0.0071 16.4 9.8 0.01 15.9 9.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.11 KER22590.1 - 0.14 11.4 3.0 0.15 11.2 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) YqzH PF14164.6 KER22590.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 YqzH-like protein DUF5373 PF17343.2 KER22590.1 - 5.1 6.9 9.2 7 6.5 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Ac76 PF05814.11 KER22590.1 - 5.4 7.1 6.7 0.2 11.7 0.6 1.8 2 0 0 2 2 2 0 Orf76 (Ac76) TRAP-gamma PF07074.12 KER22590.1 - 8.8 5.8 9.2 8.7 5.9 2.5 2.2 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Collagen PF01391.18 KER22592.1 - 5e-166 538.6 645.5 5.2e-10 38.9 18.8 21.2 2 1 10 12 12 12 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER22592.1 - 5.7e-30 104.3 0.0 9e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 KER22593.1 - 7.5e-07 29.4 10.3 1.1e-06 28.8 10.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type C domain Collagen PF01391.18 KER22594.1 - 1.5e-144 469.9 584.0 6.4e-09 35.4 25.2 18.7 2 2 9 11 11 11 8 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER22594.1 - 2e-27 96.0 0.3 5.6e-18 65.1 0.2 2.1 1 1 1 2 2 2 2 Fibrillar collagen C-terminal domain Parvo_NS1 PF01057.17 KER22596.1 - 3.5e-15 55.8 0.2 5.2e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER22596.1 - 2.2e-09 36.7 0.1 2.8e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.6 KER22596.1 - 0.0014 18.6 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KER22596.1 - 0.02 14.4 0.1 0.07 12.6 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KER22596.1 - 0.034 14.2 0.1 0.07 13.1 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4327 PF14217.6 KER22596.1 - 0.085 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) AAA_22 PF13401.6 KER22596.1 - 0.12 12.6 0.0 3.3 8.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain RIIa PF02197.17 KER22598.1 - 0.00035 20.2 0.1 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit UPF0542 PF15086.6 KER22600.1 - 0.23 11.4 1.2 0.4 10.7 1.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 FH2 PF02181.23 KER22602.1 - 1.1e-31 110.3 2.7 5.5e-29 101.4 0.2 3.4 2 2 0 2 2 2 2 Formin Homology 2 Domain CEP170_C PF15308.6 KER22602.1 - 0.1 11.2 0.5 11 4.4 0.1 2.3 2 0 0 2 2 2 0 CEP170 C-terminus DUF4071 PF13281.6 KER22602.1 - 0.13 11.3 0.1 0.28 10.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PH_BEACH PF14844.6 KER22602.1 - 0.2 11.8 1.2 37 4.5 0.0 3.1 3 0 0 3 3 3 0 PH domain associated with Beige/BEACH FmiP_Thoc5 PF09766.9 KER22604.1 - 4e-92 309.3 0.6 5.6e-92 308.8 0.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 RWD PF05773.22 KER22604.1 - 0.029 14.6 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 RWD domain Cep57_CLD_2 PF14197.6 KER22604.1 - 2.7 8.1 4.9 17 5.6 0.4 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RRM_1 PF00076.22 KER22606.1 - 1.4e-36 124.1 0.2 6.2e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER22606.1 - 7e-09 35.7 0.2 0.00094 19.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KER22606.1 - 0.0002 21.3 0.1 0.27 11.3 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KER22606.1 - 0.0015 18.6 0.2 0.14 12.2 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 KER22606.1 - 0.0043 17.3 0.3 0.064 13.5 0.1 2.6 1 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 KER22606.1 - 0.077 13.0 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 RL domain DUF4529 PF15032.6 KER22608.1 - 0.12 11.5 0.7 0.16 11.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) zf-RING_2 PF13639.6 KER22610.1 - 1.2e-13 51.1 4.0 1.2e-13 51.1 4.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KER22610.1 - 5.9e-11 41.9 0.8 5.9e-11 41.9 0.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KER22610.1 - 4.2e-09 36.1 3.5 8.4e-09 35.1 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER22610.1 - 1.8e-08 34.2 1.9 4.1e-08 33.0 1.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER22610.1 - 2.7e-08 33.5 2.1 8.1e-08 32.0 2.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER22610.1 - 3.7e-08 33.5 1.6 1.1e-07 32.1 1.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER22610.1 - 3e-06 27.2 2.8 1.3e-05 25.1 0.4 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KER22610.1 - 3.3e-05 23.7 2.1 3.3e-05 23.7 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER22610.1 - 0.00025 20.8 3.4 0.00061 19.6 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KER22610.1 - 0.0015 18.1 1.6 0.0039 16.8 1.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KER22610.1 - 0.018 15.1 2.1 0.046 13.8 2.1 1.7 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 KER22610.1 - 0.046 13.6 2.5 0.13 12.2 2.5 1.8 1 1 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 KER22610.1 - 0.077 13.1 5.6 0.31 11.1 5.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KER22610.1 - 0.26 11.5 1.9 0.86 9.8 1.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KER22610.1 - 4.6 7.6 9.2 14 6.1 2.5 2.5 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 KER22610.1 - 6.3 7.0 7.4 0.3 11.2 1.0 2.2 2 1 0 2 2 2 0 RING-variant domain FAA_hydrolase PF01557.18 KER22612.1 - 6e-20 71.8 0.0 6.8e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ArfGap PF01412.18 KER22614.1 - 2e-38 131.1 0.0 4.4e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ras PF00071.22 KER22614.1 - 6.3e-07 29.1 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Ras family PH PF00169.29 KER22614.1 - 3.9e-06 27.3 0.4 0.0032 17.9 0.1 2.6 2 0 0 2 2 2 2 PH domain Ank PF00023.30 KER22614.1 - 1.5e-05 25.2 0.3 4.3e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KER22614.1 - 0.0012 19.1 0.1 0.0029 17.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER22614.1 - 0.0014 19.2 0.2 0.0041 17.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH_6 PF15406.6 KER22614.1 - 0.003 17.8 0.2 0.0076 16.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.7 KER22614.1 - 0.0034 18.0 0.1 0.0092 16.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER22614.1 - 0.041 14.4 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat PH_11 PF15413.6 KER22614.1 - 0.17 12.3 1.2 21 5.6 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4763 PF15960.5 KER22616.1 - 0.015 14.6 0.4 0.019 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ZapB PF06005.12 KER22616.1 - 0.049 14.1 1.0 0.32 11.5 0.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Macoilin PF09726.9 KER22616.1 - 0.44 9.0 9.0 0.53 8.8 9.0 1.0 1 0 0 1 1 1 0 Macoilin family zf-DNL PF05180.12 KER22617.1 - 4.1e-26 90.7 5.0 6.8e-26 90.0 5.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 KER22617.1 - 0.024 14.7 0.8 0.047 13.7 0.8 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AFOR_C PF01314.18 KER22619.1 - 0.093 11.7 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 cNMP_binding PF00027.29 KER22621.1 - 5e-05 23.3 1.0 0.37 10.9 0.0 4.0 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain RVT_1 PF00078.27 KER22622.1 - 8.1e-17 61.5 0.0 3.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Lactamase_B PF00753.27 KER22622.1 - 1.9e-09 37.8 1.4 4.8e-08 33.2 1.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KER22622.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain zf-CCCH_7 PF18586.1 KER22622.1 - 0.15 12.4 0.2 0.96 9.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 E1_DerP2_DerF2 PF02221.15 KER22623.1 - 2.8e-19 69.9 0.1 3.2e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KER22624.1 - 4.8e-13 49.7 0.1 5.6e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 ML domain LPD30 PF18850.1 KER22624.1 - 0.036 13.8 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 E1_DerP2_DerF2 PF02221.15 KER22625.1 - 2e-22 80.1 0.1 2.5e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 ML domain Neprosin_AP PF14365.6 KER22626.1 - 0.036 14.6 2.0 0.051 14.1 2.0 1.2 1 0 0 1 1 1 0 Neprosin activation peptide Trypsin PF00089.26 KER22627.1 - 1.5e-62 211.3 0.5 2.1e-62 210.8 0.5 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KER22627.1 - 1.9e-11 44.3 0.1 2.2e-10 40.9 0.1 2.1 1 1 0 1 1 1 1 CUB domain Trypsin_2 PF13365.6 KER22627.1 - 3.9e-08 34.3 0.1 7.2e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 KER22627.1 - 1.7e-05 24.9 7.4 5.1e-05 23.4 7.4 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF1986 PF09342.11 KER22627.1 - 0.03 14.7 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sugar_tr PF00083.24 KER22628.1 - 2e-25 89.6 13.1 3.1e-25 88.9 13.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER22628.1 - 4.4e-19 68.6 24.9 2.3e-18 66.2 14.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KER22630.1 - 5.2e-28 98.1 11.8 8.2e-28 97.5 11.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER22630.1 - 2e-15 56.6 24.9 1.5e-14 53.7 23.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_kinase PF01633.20 KER22631.1 - 3.7e-18 65.9 0.9 5.4e-18 65.4 0.9 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KER22631.1 - 0.003 17.5 0.2 0.0042 17.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER22632.1 - 3.7e-33 114.9 0.1 8.3e-24 84.4 0.0 3.0 2 1 1 3 3 3 3 Choline/ethanolamine kinase APH PF01636.23 KER22632.1 - 0.0019 18.2 0.0 0.021 14.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RWD PF05773.22 KER22634.1 - 2.3e-14 53.6 0.0 4.4e-14 52.7 0.0 1.5 2 0 0 2 2 2 1 RWD domain Abhydrolase_3 PF07859.13 KER22635.1 - 2.1e-11 44.1 0.1 3.6e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KER22635.1 - 0.00026 20.6 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KER22635.1 - 0.00053 20.7 0.6 0.00091 19.9 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cellulase-like PF12876.7 KER22636.1 - 0.079 12.3 0.1 0.094 12.0 0.1 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like Peptidase_M49 PF03571.15 KER22637.1 - 1.1e-209 697.4 0.0 1.3e-209 697.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Mub_B2 PF17966.1 KER22637.1 - 0.01 16.6 0.0 0.073 13.8 0.0 2.2 2 0 0 2 2 2 1 Mub B2-like domain EF-hand_like PF09279.11 KER22639.1 - 1.9e-06 28.3 0.0 0.038 14.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like CC PF04942.14 KER22641.1 - 0.021 15.0 1.3 0.035 14.3 1.3 1.3 1 0 0 1 1 1 0 CC domain PAN_1 PF00024.26 KER22643.1 - 0.01 15.8 0.2 0.022 14.7 0.2 1.5 1 0 0 1 1 1 0 PAN domain adh_short PF00106.25 KER22644.1 - 5.1e-21 75.0 0.1 6.9e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER22644.1 - 1.6e-12 47.5 0.0 2.1e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Coiled-coil_56 PF09813.9 KER22644.1 - 0.061 13.4 0.0 5.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 EF-hand_1 PF00036.32 KER22645.1 - 4.1e-15 54.1 6.1 1.6e-08 33.5 0.7 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KER22645.1 - 1.1e-13 49.9 4.1 5.5e-08 32.1 1.1 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KER22645.1 - 1.1e-12 46.8 12.3 1.1e-07 31.0 0.8 3.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KER22645.1 - 1.6e-12 47.7 4.7 1.6e-12 47.7 4.7 1.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KER22645.1 - 3.6e-07 29.9 1.4 0.0004 20.2 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 KER22645.1 - 4.1e-07 29.8 2.7 0.017 15.0 0.1 2.4 2 0 0 2 2 2 2 EF hand DUF1456 PF07308.13 KER22645.1 - 0.0028 18.0 7.2 0.19 12.1 4.6 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1456) SPARC_Ca_bdg PF10591.9 KER22645.1 - 0.0035 17.7 1.9 0.13 12.6 1.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 KER22645.1 - 0.01 15.8 1.5 0.016 15.2 1.5 1.2 1 0 0 1 1 1 0 Caleosin related protein DUF2666 PF10869.8 KER22645.1 - 0.013 15.7 9.6 0.014 15.6 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Phage_TAC_12 PF12363.8 KER22645.1 - 0.021 15.2 4.4 0.65 10.4 3.5 2.8 1 1 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Phage_int_SAM_4 PF13495.6 KER22645.1 - 0.036 14.5 1.9 4.5 7.8 0.1 2.5 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KER22645.1 - 0.046 14.0 0.2 0.13 12.6 0.1 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3349 PF11829.8 KER22645.1 - 0.079 13.7 0.9 5.1 7.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) FliG_N PF14842.6 KER22645.1 - 0.093 13.3 0.6 0.16 12.5 0.4 1.6 1 1 0 1 1 1 0 FliG N-terminal domain DnaI_N PF07319.11 KER22645.1 - 1.4 9.7 6.2 2.5 8.8 2.5 2.3 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus Complex1_LYR_2 PF13233.6 KER22645.1 - 1.9 9.3 5.0 7.4 7.4 5.0 2.1 1 1 0 1 1 1 0 Complex1_LYR-like FKBP_N PF01346.18 KER22645.1 - 3.4 8.7 6.9 1.1e+02 3.9 6.9 2.4 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase EF-hand_1 PF00036.32 KER22646.1 - 9.5e-16 56.1 1.3 1.7e-07 30.3 0.7 2.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER22646.1 - 4.3e-14 51.3 1.9 8.6e-07 28.2 0.6 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER22646.1 - 6.4e-14 52.2 0.4 7.4e-14 52.0 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER22646.1 - 9.8e-14 50.1 0.7 4.7e-07 29.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KER22646.1 - 1.5e-10 40.7 0.5 1.4e-05 24.8 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EspA PF03433.13 KER22646.1 - 0.002 18.0 2.3 0.0037 17.1 2.3 1.5 1 1 0 1 1 1 1 EspA-like secreted protein EF-hand_4 PF12763.7 KER22646.1 - 0.011 15.6 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF1456 PF07308.13 KER22646.1 - 0.011 16.0 0.8 0.029 14.7 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) SPARC_Ca_bdg PF10591.9 KER22646.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 KER22646.1 - 0.024 14.4 0.0 0.72 9.7 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 KER22646.1 - 0.069 13.1 0.1 2.5 8.0 0.1 2.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_9 PF14658.6 KER22646.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KER22648.1 - 4.2e-13 47.8 0.8 1.2e-08 33.9 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER22648.1 - 4.3e-13 48.0 0.9 4.7e-08 32.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER22648.1 - 1.1e-11 45.0 2.1 5.6e-07 29.9 0.3 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER22648.1 - 9.5e-09 35.0 0.9 2.1e-08 33.8 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KER22648.1 - 8.4e-08 31.4 0.7 2e-06 27.0 0.2 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KER22648.1 - 0.0058 16.9 1.6 0.04 14.3 0.6 1.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KER22648.1 - 0.015 15.6 0.5 0.04 14.3 0.5 1.7 1 1 0 1 1 1 0 EF-hand domain EF-hand_9 PF14658.6 KER22648.1 - 0.019 15.3 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_10 PF14788.6 KER22648.1 - 0.03 14.2 1.3 0.51 10.2 0.7 2.3 1 1 1 2 2 2 0 EF hand EF-hand_like PF09279.11 KER22648.1 - 0.052 14.0 0.7 0.31 11.6 0.3 2.0 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 KER22649.1 - 1.4e-11 43.4 0.2 2.2e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER22649.1 - 2.3e-10 39.3 2.2 1e-07 31.0 0.2 2.4 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER22649.1 - 9.6e-10 38.2 1.4 4.8e-08 32.7 0.4 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 KER22649.1 - 1e-09 38.7 0.4 3.9e-09 36.8 0.4 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER22649.1 - 1.1e-06 27.8 0.2 1.1e-06 27.8 0.2 3.1 3 1 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 KER22649.1 - 0.00094 19.5 0.2 0.002 18.5 0.2 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER22649.1 - 0.0049 17.2 0.0 0.0054 17.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain DUF2043 PF09740.9 KER22651.1 - 3.6e-11 43.7 2.1 1.1e-10 42.1 0.4 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) tRNA_anti-codon PF01336.25 KER22651.1 - 0.036 14.1 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF5641 PF18701.1 KER22654.1 - 4.8e-19 68.3 0.8 9.5e-19 67.4 0.8 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5641) Exo_endo_phos PF03372.23 KER22655.1 - 3.5e-05 23.4 0.0 8.7e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER22655.1 - 0.12 12.3 0.1 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Fez1 PF06818.15 KER22656.1 - 0.0055 17.2 29.7 0.0055 17.2 29.7 5.0 1 1 4 5 5 5 3 Fez1 zf-C2H2 PF00096.26 KER22657.1 - 0.0064 16.9 3.9 0.0064 16.9 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22657.1 - 0.0066 17.2 4.1 0.042 14.7 4.1 2.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER22657.1 - 0.011 16.1 7.9 0.071 13.6 1.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Dynactin PF12455.8 KER22657.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Dynein associated protein RVT_1 PF00078.27 KER22658.1 - 1.2e-08 34.7 0.0 3.2e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myosin_head PF00063.21 KER22660.1 - 3.4e-158 527.9 0.0 1.8e-113 380.1 0.0 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 KER22660.1 - 1.4e-15 57.7 0.0 1.6e-12 47.9 0.0 3.7 2 1 0 2 2 2 1 MyTH4 domain AAA_30 PF13604.6 KER22660.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain IQ PF00612.27 KER22660.1 - 0.0029 17.3 0.8 0.0029 17.3 0.8 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif FERM_M PF00373.18 KER22660.1 - 0.0061 17.0 0.1 0.028 14.8 0.1 2.2 1 1 0 1 1 1 1 FERM central domain HDV_ag PF01517.18 KER22660.1 - 0.017 15.0 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen AAA_16 PF13191.6 KER22660.1 - 0.029 14.7 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KER22660.1 - 0.055 13.7 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.15 KER22663.1 - 3.2e-19 68.3 0.5 5.2e-19 67.7 0.5 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KER22663.1 - 0.043 13.5 0.5 0.14 11.9 0.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Rcd1 PF04078.13 KER22664.1 - 1.3e-121 404.8 0.3 1.5e-121 404.6 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF742 PF05331.11 KER22664.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Myelin_PLP PF01275.19 KER22665.1 - 1e-23 84.4 7.0 1.4e-23 84.0 7.0 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF4064 PF13273.6 KER22665.1 - 0.92 9.8 6.1 0.34 11.2 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Glyco_hydr_116N PF12215.8 KER22666.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term SH3_1 PF00018.28 KER22669.1 - 0.00028 20.4 0.0 0.00057 19.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PIF1 PF05970.14 KER22671.1 - 2.4e-37 129.0 0.2 9e-36 123.8 0.2 2.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KER22671.1 - 1.3e-09 38.1 0.0 8.7e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KER22671.1 - 0.0072 16.7 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KER22671.1 - 0.03 14.1 1.1 0.16 11.8 0.4 2.7 3 1 0 3 3 3 0 UvrD-like helicase C-terminal domain WD40 PF00400.32 KER22672.1 - 4.1e-18 65.4 0.8 6.6e-06 26.8 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22672.1 - 4.1e-07 30.2 0.0 0.015 15.6 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER22672.1 - 1.6e-05 24.9 0.0 0.034 14.0 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KER22672.1 - 0.012 15.6 0.4 4.3 7.4 0.0 3.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat NHL PF01436.21 KER22672.1 - 0.037 14.1 0.2 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 NHL repeat WD40 PF00400.32 KER22673.1 - 7.4e-14 51.9 20.8 0.011 16.6 0.1 9.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22673.1 - 2e-05 24.8 0.0 0.37 11.1 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER22673.1 - 0.0034 16.1 0.0 0.025 13.3 0.0 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Vps51 PF08700.11 KER22675.1 - 7 6.8 11.6 0.31 11.2 0.4 4.0 3 0 0 3 3 3 0 Vps51/Vps67 Pyr_redox_2 PF07992.14 KER22676.1 - 2.1e-70 237.3 1.2 2.7e-70 236.9 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KER22676.1 - 1.5e-38 131.4 0.0 5.8e-38 129.5 0.0 2.0 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KER22676.1 - 3.9e-20 72.2 5.8 1.6e-17 63.8 1.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KER22676.1 - 7e-11 42.1 9.6 2e-09 37.3 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KER22676.1 - 6.5e-10 38.8 0.9 8.1e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KER22676.1 - 3.4e-09 36.3 3.1 1e-07 31.4 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KER22676.1 - 3.2e-07 29.8 0.6 3.2e-07 29.8 0.6 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KER22676.1 - 3.9e-07 30.2 1.9 0.00022 21.4 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KER22676.1 - 6.5e-06 25.6 6.1 0.023 14.0 0.5 3.2 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 KER22676.1 - 0.0001 21.7 1.6 0.12 11.6 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KER22676.1 - 0.00012 20.9 8.8 0.0012 17.6 0.7 3.6 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KER22676.1 - 0.00023 20.5 1.6 0.00099 18.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KER22676.1 - 0.0036 16.5 0.6 0.44 9.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KER22676.1 - 0.1 12.0 0.3 8.5 5.7 0.1 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KER22676.1 - 0.11 12.0 8.2 3.2 7.2 0.5 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase UPF0227 PF05728.12 KER22676.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0227) UDPG_MGDP_dh_N PF03721.14 KER22676.1 - 0.24 11.0 8.5 2 8.0 1.6 3.3 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KER22676.1 - 0.8 8.7 4.7 1.8 7.5 0.4 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KER22676.1 - 2.6 7.9 6.0 1.9 8.4 0.5 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_IclR PF09339.10 KER22679.1 - 0.019 14.7 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain STAT_int PF02865.17 KER22679.1 - 0.076 13.5 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 STAT protein, protein interaction domain Phage_AlpA PF05930.12 KER22679.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Tnp_IS630 PF01710.16 KER22679.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Transposase Innexin PF00876.18 KER22680.1 - 1.5e-135 452.0 0.0 2.2e-135 451.5 0.0 1.2 1 0 0 1 1 1 1 Innexin SelP_N PF04592.14 KER22680.1 - 7.3 5.9 8.7 12 5.2 8.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3079 PF11278.8 KER22682.1 - 0.049 13.4 0.0 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) Tubulin PF00091.25 KER22683.1 - 7.2e-13 49.2 0.0 3.2e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Innexin PF00876.18 KER22684.1 - 2.4e-54 184.9 0.6 2.7e-54 184.8 0.6 1.0 1 0 0 1 1 1 1 Innexin Phage_TAC_6 PF09550.10 KER22684.1 - 0.14 12.6 0.9 0.26 11.7 0.9 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC MogR_DNAbind PF12181.8 KER22685.1 - 0.036 14.0 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) RVT_1 PF00078.27 KER22687.1 - 4.7e-16 59.0 0.0 5.6e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adaptin_binding PF10199.9 KER22688.1 - 1.4e-10 41.8 2.1 2.4e-10 41.1 2.1 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 gag-asp_proteas PF13975.6 KER22688.1 - 3.1e-05 24.5 0.0 6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER22688.1 - 0.00058 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER22688.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease LSM PF01423.22 KER22689.1 - 1.3e-17 63.2 0.2 1.7e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.8 KER22689.1 - 3.1 8.4 7.4 0.73 10.4 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) E1_DerP2_DerF2 PF02221.15 KER22690.1 - 8.2e-10 39.2 1.1 1.8e-09 38.2 1.1 1.5 1 0 0 1 1 1 1 ML domain Strep_pep PF14404.6 KER22690.1 - 0.014 15.6 0.0 5.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species Exo_endo_phos_2 PF14529.6 KER22692.1 - 2e-07 30.9 0.1 4.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER22692.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KER22692.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WW PF00397.26 KER22694.1 - 9.9e-07 28.7 0.9 2.5e-06 27.5 0.9 1.8 1 0 0 1 1 1 1 WW domain YL1 PF05764.13 KER22694.1 - 1.9e-05 24.9 9.7 1.9e-05 24.9 9.7 1.4 2 0 0 2 2 2 1 YL1 nuclear protein Zn_Tnp_IS91 PF14319.6 KER22694.1 - 0.038 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain TMEM171 PF15471.6 KER22694.1 - 1.4 7.9 5.2 1 8.3 3.3 1.6 2 0 0 2 2 2 0 Transmembrane protein family 171 Nop10p PF04135.12 KER22696.1 - 5.3e-21 74.4 1.1 6.1e-21 74.2 1.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family E2F_CC-MB PF16421.5 KER22697.1 - 1.8e-26 92.3 0.6 1.8e-26 92.3 0.6 1.8 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KER22697.1 - 2.1e-24 85.4 0.2 5.4e-24 84.0 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Baculo_PEP_C PF04513.12 KER22697.1 - 0.014 15.4 0.3 0.024 14.7 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KER22697.1 - 0.019 15.2 2.9 0.019 15.2 2.9 2.3 3 0 0 3 3 3 0 Haemolysin XhlA JIP_LZII PF16471.5 KER22697.1 - 0.06 13.5 1.2 0.11 12.7 1.2 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II T6PP_N PF18572.1 KER22697.1 - 0.084 12.7 0.1 0.34 10.8 0.1 2.0 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Nucleoporin_C PF03177.14 KER22698.1 - 1.9e-06 27.0 0.0 0.00097 18.0 0.1 2.5 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal RYDR_ITPR PF01365.21 KER22699.1 - 1.6e-124 413.0 0.7 8.1e-49 165.8 0.3 3.7 3 0 0 3 3 3 3 RIH domain RyR PF02026.16 KER22699.1 - 1.5e-103 339.2 0.2 1.4e-28 98.9 0.0 5.2 5 0 0 5 5 5 4 RyR domain SPRY PF00622.28 KER22699.1 - 1.8e-41 141.0 0.1 7.1e-17 61.6 0.0 4.2 4 1 0 4 4 4 3 SPRY domain RR_TM4-6 PF06459.12 KER22699.1 - 4.2e-32 112.1 0.0 4.2e-32 112.1 0.0 2.6 3 0 0 3 3 2 1 Ryanodine Receptor TM 4-6 RIH_assoc PF08454.11 KER22699.1 - 4.7e-31 106.6 0.0 1.4e-27 95.4 0.0 3.8 3 0 0 3 3 3 2 RyR and IP3R Homology associated MIR PF02815.19 KER22699.1 - 3.1e-27 95.6 0.0 1.2e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 KER22699.1 - 2.4e-09 36.8 17.0 2.6e-08 33.4 17.0 2.3 1 1 0 1 1 1 1 Ion transport protein EF-hand_7 PF13499.6 KER22699.1 - 4e-09 36.8 0.1 1.4e-08 35.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER22699.1 - 1.6e-06 27.3 0.0 0.074 12.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KER22699.1 - 1e-05 24.7 0.2 0.03 13.9 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER22699.1 - 5.6e-05 22.9 0.1 0.00023 20.9 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KER22699.1 - 9.5e-05 22.0 0.2 0.055 13.4 0.0 3.0 1 1 1 2 2 2 1 EF-hand domain Ins145_P3_rec PF08709.11 KER22699.1 - 0.18 11.0 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Symplekin_C PF12295.8 KER22700.1 - 1.8e-57 194.5 0.4 4e-57 193.3 0.4 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KER22700.1 - 1.7e-43 148.9 0.0 3.5e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DDOST_48kD PF03345.14 KER22702.1 - 7.3e-142 473.0 0.1 8.4e-142 472.8 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta zf-C2H2_2 PF12756.7 KER22703.1 - 5.2e-12 46.0 0.4 4.2e-11 43.1 0.1 2.5 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 KER22703.1 - 0.2 11.8 1.2 4.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) BAR PF03114.18 KER22704.1 - 1.7e-24 86.8 1.8 2e-24 86.5 1.8 1.0 1 0 0 1 1 1 1 BAR domain DUF4404 PF14357.6 KER22704.1 - 0.052 14.2 0.8 0.25 12.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CobA_CobO_BtuR PF02572.15 KER22704.1 - 0.053 13.8 0.2 0.084 13.1 0.2 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Endotoxin_C2 PF18449.1 KER22704.1 - 0.069 13.5 2.0 0.2 12.0 2.0 1.9 1 0 0 1 1 1 0 Delta endotoxin Ntox3 PF15536.6 KER22708.1 - 0.086 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 3 EF-hand_6 PF13405.6 KER22710.1 - 4.9e-22 75.9 5.0 2.5e-06 27.0 0.0 4.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 KER22710.1 - 8.1e-20 68.8 7.2 2e-05 23.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER22710.1 - 1.3e-19 70.4 4.1 3.8e-09 36.9 1.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KER22710.1 - 2.7e-13 49.6 6.6 9.3e-08 31.8 0.5 4.2 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 KER22710.1 - 3.5e-13 48.4 5.4 0.0001 21.7 0.0 4.6 4 0 0 4 4 4 3 EF hand p25-alpha PF05517.12 KER22710.1 - 0.019 15.1 0.0 7.9 6.6 0.1 2.3 2 0 0 2 2 2 0 p25-alpha EF-hand_11 PF08976.11 KER22710.1 - 0.038 14.9 0.0 0.065 14.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 KER22710.1 - 0.061 13.3 0.2 12 5.7 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein Ribosomal_L18 PF17135.4 KER22710.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e CAP PF00188.26 KER22711.1 - 1.7e-06 28.9 5.1 3e-06 28.1 5.1 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Arrestin_N PF00339.29 KER22712.1 - 2.6e-14 53.5 0.2 1.5e-13 51.0 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KER22712.1 - 0.00012 22.5 0.4 1.1 9.7 0.0 4.0 5 0 0 5 5 5 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 KER22712.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Rgp1 Coleoptericin PF06286.11 KER22712.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Coleoptericin CAP PF00188.26 KER22713.1 - 6.7e-06 27.0 0.2 7e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KER22714.1 - 0.00099 19.9 0.1 0.0011 19.8 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KER22715.1 - 0.012 16.4 0.0 0.013 16.3 0.0 1.1 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 KER22716.1 - 2.1e-16 60.9 1.0 1.9e-11 44.9 0.3 2.7 2 1 0 2 2 2 2 Cysteine-rich secretory protein family CAP PF00188.26 KER22717.1 - 3.6e-11 44.0 3.1 3.8e-05 24.5 1.2 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family EGF_alliinase PF04863.13 KER22717.1 - 0.27 11.7 6.4 0.39 11.2 0.0 3.4 4 0 0 4 4 4 0 Alliinase EGF-like domain HSF_DNA-bind PF00447.17 KER22720.1 - 1.2e-28 99.6 0.1 2.5e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding HALZ PF02183.18 KER22720.1 - 0.063 13.5 1.1 0.16 12.2 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper HAP1_N PF04849.13 KER22720.1 - 0.092 11.9 0.2 0.17 11.1 0.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CAP PF00188.26 KER22721.1 - 1.2e-16 61.7 0.0 5.4e-15 56.4 0.0 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KER22722.1 - 2.7e-21 76.7 0.9 2.7e-21 76.7 0.9 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family CEBP1_N PF16368.5 KER22722.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus PTPlike_phytase PF14566.6 KER22723.1 - 3.8e-20 72.6 0.1 2e-13 50.8 0.0 3.9 3 1 0 3 3 3 2 Inositol hexakisphosphate Linker_histone PF00538.19 KER22723.1 - 1.3e-12 47.9 0.9 1.5e-05 25.2 0.2 2.7 2 0 0 2 2 2 2 linker histone H1 and H5 family Ldh_1_N PF00056.23 KER22724.1 - 1.1e-07 32.0 0.9 2.9e-07 30.7 0.5 1.8 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain MDFI PF15316.6 KER22724.1 - 0.12 12.5 0.4 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Ldh_1_C PF02866.18 KER22725.1 - 4.7e-11 42.9 0.0 5.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4C PF11975.8 KER22725.1 - 0.027 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Pescadillo_N PF06732.11 KER22726.1 - 4.6e-89 298.6 0.1 9.1e-89 297.6 0.1 1.4 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 KER22726.1 - 2.9e-07 30.8 0.0 6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HD_2 PF12917.7 KER22726.1 - 0.044 13.5 0.5 0.15 11.8 0.7 1.7 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme zf-LITAF-like PF10601.9 KER22728.1 - 5.1e-25 87.5 10.1 7.5e-25 87.0 10.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.11 KER22728.1 - 0.0015 18.0 1.0 0.4 10.3 0.1 2.3 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) YacG PF03884.14 KER22728.1 - 2 8.2 8.9 6 6.7 0.2 3.1 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Prominin PF05478.11 KER22728.1 - 3.9 5.3 6.6 3.5 5.5 6.6 1.0 1 0 0 1 1 1 0 Prominin V-set PF07686.17 KER22731.1 - 2.3e-06 27.7 2.7 0.017 15.3 0.2 2.9 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 KER22731.1 - 0.0011 19.6 0.8 3.6 8.3 0.2 3.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER22731.1 - 0.0027 17.7 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KER22731.1 - 0.0036 17.6 0.5 1.2 9.5 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 KER22731.1 - 0.038 13.6 0.3 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain ACT_5 PF13710.6 KER22731.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 ACT domain GCV_T PF01571.21 KER22732.1 - 2.2e-07 30.5 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF844 PF05815.11 KER22733.1 - 0.08 12.1 0.4 0.15 11.2 0.4 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Pkinase PF00069.25 KER22734.1 - 1e-69 234.8 0.0 1.3e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22734.1 - 1.6e-30 106.3 0.0 2.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KER22734.1 - 9.7e-12 45.1 0.0 3e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KER22734.1 - 0.00019 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER22734.1 - 0.0005 19.5 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KER22734.1 - 0.0013 17.8 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KER22734.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KER22734.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KER22734.1 - 0.044 12.7 0.2 0.071 12.0 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Yop-YscD_cpl PF16697.5 KER22734.1 - 0.072 13.4 0.0 1.7 9.0 0.0 2.8 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain YrbL-PhoP_reg PF10707.9 KER22734.1 - 0.1 12.1 0.2 0.64 9.5 0.2 2.1 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL PAX PF00292.18 KER22737.1 - 7.5e-68 226.2 0.5 1.4e-67 225.4 0.5 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 KER22737.1 - 1.2e-21 76.3 2.3 3.6e-21 74.8 2.3 1.9 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 KER22737.1 - 0.00092 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 KER22737.1 - 0.039 13.6 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Homeobox_KN PF05920.11 KER22737.1 - 0.041 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Homeobox KN domain PGBA_C PF15437.6 KER22737.1 - 0.16 12.4 1.2 0.41 11.1 1.2 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Zn_peptidase_2 PF04298.12 KER22737.1 - 0.18 11.2 1.9 0.39 10.1 1.9 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF4148 PF13663.6 KER22737.1 - 3.1 8.1 5.6 29 4.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) K_channel_TID PF07941.11 KER22737.1 - 4.8 7.7 10.3 4.6 7.8 0.7 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain G_glu_transpept PF01019.21 KER22739.1 - 6.1e-52 177.1 0.0 1.6e-51 175.7 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Endosulfine PF04667.17 KER22740.1 - 3e-07 30.5 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region LCAT PF02450.15 KER22741.1 - 4.2e-47 161.2 0.0 8.8e-40 137.1 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KER22741.1 - 7.6e-07 30.0 0.0 1.3e-06 29.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 KER22741.1 - 0.04 13.0 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.13 KER22741.1 - 0.058 13.1 0.0 1.4 8.6 0.0 2.3 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KER22741.1 - 0.098 12.3 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER22741.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KER22742.1 - 1.6e-34 119.8 0.0 8.3e-27 94.3 0.0 2.0 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KER22742.1 - 9.4e-05 22.2 0.0 0.0021 17.8 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KER22742.1 - 0.00014 22.5 0.0 0.0003 21.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KER22742.1 - 0.0003 20.2 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KER22742.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.11 KER22742.1 - 0.033 13.5 0.1 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 KER22742.1 - 0.045 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1749 PF08538.10 KER22742.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TIMELESS PF04821.14 KER22743.1 - 5.1e-55 186.7 1.1 5.1e-55 186.7 1.1 2.3 3 0 0 3 3 3 1 Timeless protein RVT_1 PF00078.27 KER22743.1 - 1.7e-15 57.1 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3_4 PF16794.5 KER22745.1 - 1.8e-28 98.5 0.1 2.9e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Fibronectin-III type domain Peptidase_C2 PF00648.21 KER22746.1 - 1.2e-05 24.5 0.1 8.3e-05 21.7 0.0 1.9 1 1 1 2 2 2 2 Calpain family cysteine protease IQ PF00612.27 KER22750.1 - 0.1 12.4 4.9 0.04 13.7 1.0 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif HECT PF00632.25 KER22751.1 - 2e-85 287.0 0.0 3.7e-85 286.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KER22751.1 - 0.14 12.1 0.3 0.45 10.5 0.3 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif NAD_Gly3P_dh_C PF07479.14 KER22752.1 - 5.8e-35 120.6 0.0 1e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KER22752.1 - 5.3e-32 111.0 0.0 7.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KER22752.1 - 0.15 12.6 0.1 1.7 9.3 0.1 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2373 PF10180.9 KER22753.1 - 0.086 12.7 0.0 29 4.6 0.0 4.3 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2373) Iwr1 PF08574.10 KER22756.1 - 9.7e-13 48.9 10.5 9.7e-13 48.9 10.5 2.1 2 0 0 2 2 2 1 Transcription factor Iwr1 FXMRP1_C_core PF12235.8 KER22756.1 - 0.023 15.3 6.8 0.036 14.7 6.8 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal SDA1 PF05285.12 KER22756.1 - 0.033 13.6 12.0 0.046 13.1 12.0 1.1 1 0 0 1 1 1 0 SDA1 RPGR1_C PF18111.1 KER22757.1 - 7.2e-43 146.3 1.7 4.2e-27 95.1 0.0 3.3 3 0 0 3 3 3 2 Retinitis pigmentosa G-protein regulator interacting C-terminal C2-C2_1 PF11618.8 KER22757.1 - 1.6e-30 106.0 0.0 7.7e-26 90.9 0.0 3.3 2 1 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 C2 PF00168.30 KER22757.1 - 9.4e-05 22.7 0.0 0.00048 20.4 0.0 2.2 2 0 0 2 2 2 1 C2 domain Anoctamin PF04547.12 KER22758.1 - 0.023 13.5 1.5 0.027 13.3 1.5 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel EphA2_TM PF14575.6 KER22758.1 - 0.096 13.6 1.9 0.13 13.1 1.9 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 KER22758.1 - 0.099 12.5 3.3 0.14 12.1 3.3 1.2 1 0 0 1 1 1 0 TMEM9 DUF2207 PF09972.9 KER22758.1 - 0.45 9.2 1.2 0.48 9.1 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KER22758.1 - 0.62 10.4 6.7 0.88 9.9 6.7 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 KER22758.1 - 0.76 9.7 10.3 1 9.2 10.3 1.2 1 0 0 1 1 1 0 TMEM154 protein family Sigma_reg_N PF13800.6 KER22758.1 - 1.8 8.9 10.9 3.4 8.0 10.9 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4834 PF16118.5 KER22758.1 - 3.2 8.8 8.2 4.5 8.3 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ASFV_J13L PF05568.11 KER22758.1 - 4.5 7.0 9.0 8.5 6.1 9.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3139 PF11337.8 KER22759.1 - 2.8 8.6 6.3 24 5.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Ldl_recept_a PF00057.18 KER22762.1 - 6.8e-249 803.8 395.8 5.4e-12 45.7 7.6 27.1 26 0 0 26 26 26 26 Low-density lipoprotein receptor domain class A Ig_3 PF13927.6 KER22762.1 - 1.9e-15 57.2 4.4 1.4e-10 41.7 0.0 7.2 8 1 1 9 9 9 2 Immunoglobulin domain ig PF00047.25 KER22762.1 - 9.4e-12 44.9 0.0 7.7e-07 29.2 0.0 5.8 7 0 0 7 7 7 2 Immunoglobulin domain Ig_2 PF13895.6 KER22762.1 - 2.3e-11 43.8 1.1 0.0016 18.7 0.0 8.4 9 0 0 9 9 9 1 Immunoglobulin domain I-set PF07679.16 KER22762.1 - 4.2e-11 42.8 0.0 2.2e-08 34.0 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin I-set domain V-set PF07686.17 KER22762.1 - 0.00037 20.7 0.0 0.9 9.7 0.0 4.6 4 0 0 4 4 4 1 Immunoglobulin V-set domain BBS1 PF14779.6 KER22768.1 - 3.7e-15 56.1 0.0 6.9e-15 55.2 0.0 1.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS1 PF14779.6 KER22769.1 - 5.9e-32 111.1 2.6 2.3e-21 76.4 0.0 2.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 1 zf-MYND PF01753.18 KER22771.1 - 6.4e-10 38.9 4.0 1.7e-09 37.6 4.0 1.8 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.6 KER22771.1 - 0.0005 20.1 2.4 0.26 11.6 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER22771.1 - 0.001 19.3 6.0 0.28 11.5 1.5 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER22771.1 - 0.0023 17.7 0.8 0.1 12.5 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER22771.1 - 0.0073 16.4 4.9 0.054 13.6 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER22771.1 - 0.0088 15.4 3.0 0.012 15.0 3.0 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_20 PF14561.6 KER22771.1 - 0.022 15.1 1.2 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 KER22771.1 - 0.038 14.1 3.4 8.4 6.6 5.7 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_4 PF07721.14 KER22771.1 - 0.047 14.3 2.0 5.9 7.8 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat vATP-synt_E PF01991.18 KER22771.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit TPR_16 PF13432.6 KER22771.1 - 0.97 10.1 4.4 1.6 9.5 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB_C PF08482.10 KER22772.1 - 1.9 8.9 5.2 1.7 9.1 0.2 2.8 3 0 0 3 3 3 0 ATP-dependent helicase C-terminal TraC PF07820.12 KER22772.1 - 4.1 7.8 11.0 4.2 7.8 1.1 3.6 3 0 0 3 3 3 0 TraC-like protein STAG PF08514.11 KER22773.1 - 2e-36 124.3 0.4 6.5e-36 122.7 0.4 1.9 1 0 0 1 1 1 1 STAG domain MerR-DNA-bind PF09278.11 KER22773.1 - 0.052 14.1 1.7 19 5.9 1.4 3.4 2 0 0 2 2 2 0 MerR, DNA binding Peptidase_C1 PF00112.23 KER22775.1 - 1.8e-08 34.8 0.1 3.1e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Nop14 PF04147.12 KER22775.1 - 3.2e-05 22.4 15.4 4.1e-05 22.0 15.4 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KER22775.1 - 0.00055 19.5 16.8 0.00072 19.1 16.8 1.1 1 0 0 1 1 1 1 SDA1 Drc1-Sld2 PF11719.8 KER22775.1 - 0.0015 18.2 0.6 0.0017 18.0 0.6 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein DNA_pol_phi PF04931.13 KER22775.1 - 0.012 13.7 38.7 0.016 13.4 38.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KER22775.1 - 0.013 13.9 14.8 0.017 13.5 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KER22775.1 - 0.05 12.1 15.2 0.061 11.8 15.2 1.0 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 KER22775.1 - 0.063 13.1 3.8 0.078 12.8 3.8 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 KER22775.1 - 0.21 10.4 2.5 0.23 10.2 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IFT57 PF10498.9 KER22775.1 - 0.28 10.1 3.9 0.37 9.7 3.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RRN3 PF05327.11 KER22775.1 - 0.46 9.0 23.1 0.6 8.6 23.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 KER22775.1 - 0.66 9.9 25.1 0.81 9.6 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 KER22775.1 - 0.73 9.4 16.2 1.2 8.7 16.2 1.4 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 KER22775.1 - 1 9.4 22.4 1.5 8.8 22.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.12 KER22775.1 - 2.4 7.5 18.8 3.4 7.0 18.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-C3HC4 PF00097.25 KER22777.1 - 3.9e-06 26.6 5.4 8.4e-06 25.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER22777.1 - 0.0054 16.7 9.7 0.016 15.2 9.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER22777.1 - 0.017 15.1 10.4 0.043 13.8 9.9 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER22777.1 - 0.017 15.0 11.5 0.033 14.0 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER22777.1 - 0.054 13.3 8.3 0.041 13.7 4.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER22777.1 - 0.1 12.9 12.8 0.3 11.4 12.8 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KER22777.1 - 0.18 12.0 7.9 0.4 10.9 7.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RVT_1 PF00078.27 KER22778.1 - 4.7e-18 65.5 0.0 9.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNTTIP1_dimer PF18192.1 KER22780.1 - 4.4e-25 87.8 0.5 7.4e-25 87.1 0.5 1.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain CBP_BcsO PF17037.5 KER22783.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO ArsA_ATPase PF02374.15 KER22784.1 - 1.7e-109 365.7 0.4 4.7e-94 315.0 0.0 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 KER22784.1 - 5.9e-11 42.6 0.0 1.6e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KER22784.1 - 6.4e-09 35.9 0.1 2e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KER22784.1 - 1.1e-05 25.1 0.6 0.00059 19.4 0.0 3.0 3 1 1 4 4 4 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KER22784.1 - 5.3e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KER22784.1 - 0.00024 20.7 0.0 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 KER22784.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 KER22784.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KER22784.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KER22784.1 - 0.14 12.1 0.6 0.86 9.5 0.1 2.4 2 1 1 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 KER22784.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 KER22787.1 - 4.5e-68 229.5 0.0 6.6e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22787.1 - 2.4e-27 95.9 0.0 3.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 KER22787.1 - 4.7e-14 52.7 0.5 1.5e-12 47.8 0.2 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain PH PF00169.29 KER22787.1 - 3.1e-05 24.4 0.0 7.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KER22787.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KER22787.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 KER22790.1 - 1.7e-34 119.3 50.4 2.6e-28 99.0 33.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KER22790.1 - 9.9e-10 37.8 21.2 5.5e-08 32.1 21.2 2.7 1 1 0 1 1 1 1 MFS_1 like family zf-C2H2 PF00096.26 KER22791.1 - 1.9e-23 81.6 54.2 4.9e-05 23.6 0.3 7.9 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22791.1 - 2.2e-16 59.2 53.1 0.005 17.6 1.6 8.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER22791.1 - 2.1e-11 43.7 59.2 4.7e-05 23.6 0.1 9.5 10 0 0 10 10 9 4 Zinc-finger double domain zf-met PF12874.7 KER22791.1 - 0.0021 18.4 27.6 0.094 13.1 0.1 7.3 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER22791.1 - 0.0034 17.6 26.0 0.043 14.1 0.0 7.5 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER22791.1 - 0.0063 16.5 39.0 0.11 12.5 1.3 6.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-Di19 PF05605.12 KER22791.1 - 0.0064 16.8 0.0 0.0064 16.8 0.0 6.1 5 1 1 6 6 5 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KER22791.1 - 0.075 12.8 0.2 0.075 12.8 0.2 6.3 7 0 0 7 7 6 0 zinc-finger C2H2-type zf-LYAR PF08790.11 KER22791.1 - 0.24 11.4 0.1 0.24 11.4 0.1 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 KER22791.1 - 1.2 9.3 24.7 16 5.7 0.1 6.4 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1075 PF06388.11 KER22791.1 - 1.5 8.9 7.7 1.9 8.5 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) LIM PF00412.22 KER22791.1 - 3.8 7.8 21.5 5.1 7.4 4.8 4.1 3 2 0 3 3 3 0 LIM domain MVP_shoulder PF11978.8 KER22792.1 - 2.8e-52 175.7 0.1 5.4e-52 174.8 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 KER22792.1 - 8.3e-51 169.9 0.9 1.7e-14 53.7 0.0 5.1 5 1 0 5 5 5 4 Major Vault Protein repeat domain Vault_2 PF17794.1 KER22792.1 - 1.5e-42 143.7 0.3 1.9e-28 98.6 0.1 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 KER22792.1 - 1.6e-33 114.5 0.5 2.1e-30 104.6 0.0 4.3 4 0 0 4 4 4 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 KER22792.1 - 3e-27 94.5 0.2 5.8e-25 87.2 0.2 3.7 4 0 0 4 4 4 1 Major Vault Protein repeat domain MVP_shoulder PF11978.8 KER22793.1 - 2.5e-48 163.0 0.0 4.4e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 KER22793.1 - 8.7e-48 160.2 2.8 1.7e-13 50.5 0.0 5.2 5 0 0 5 5 5 4 Major Vault Protein repeat domain Vault_3 PF17795.1 KER22793.1 - 7.1e-35 118.9 1.3 8.7e-32 109.0 0.1 3.0 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 KER22793.1 - 4.5e-33 113.4 0.4 9.9e-19 67.5 0.2 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 KER22793.1 - 4.4e-26 90.7 0.3 3e-24 84.9 0.2 3.1 3 0 0 3 3 3 1 Major Vault Protein repeat domain DUF3601 PF12208.8 KER22793.1 - 0.019 15.1 0.0 7.8 6.7 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3601) Cytochrom_C1 PF02167.15 KER22794.1 - 6.9e-93 310.4 0.1 8.6e-93 310.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KER22794.1 - 0.00032 21.0 0.0 0.00075 19.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KER22794.1 - 0.0025 18.9 0.0 0.0097 17.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c UCR_Fe-S_N PF10399.9 KER22794.1 - 5.4 6.4 6.3 6.3 6.2 0.0 2.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Metallophos_C PF14008.6 KER22795.1 - 1.2e-22 80.5 0.1 4e-22 78.8 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 KER22795.1 - 4.9e-22 79.4 0.7 9.7e-22 78.5 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KER22795.1 - 1.1e-18 67.6 0.2 2.1e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Corona_RPol_N PF06478.13 KER22795.1 - 0.15 11.0 0.4 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus Metallophos PF00149.28 KER22796.1 - 3.4e-21 76.7 2.1 6.2e-21 75.8 0.8 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KER22796.1 - 2.5e-19 69.9 0.0 7.8e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KER22796.1 - 2.6e-19 69.6 0.1 4.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain MFS_1 PF07690.16 KER22797.1 - 1e-54 185.8 29.1 6e-54 183.3 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 KER22799.1 - 9.3e-13 48.4 0.0 9.3e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 C2 domain UDPGP PF01704.18 KER22804.1 - 4e-184 612.0 0.0 4.6e-184 611.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Bap31_Bap29_C PF18035.1 KER22804.1 - 0.012 15.6 0.1 5.5 7.1 0.0 2.8 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain VHS PF00790.19 KER22805.1 - 2.6e-36 124.6 0.0 5.3e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KER22805.1 - 1.1e-21 77.0 1.0 3.4e-21 75.3 1.0 1.9 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 KER22805.1 - 0.046 13.8 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 ENTH domain TBPIP PF07106.13 KER22806.1 - 1.4e-17 63.3 0.1 1.4e-17 63.3 0.1 1.6 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 KER22806.1 - 9.3e-14 51.3 0.1 1.9e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Baculo_PEP_C PF04513.12 KER22806.1 - 0.0021 18.1 3.1 0.0051 16.9 2.6 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 KER22806.1 - 0.0031 17.9 3.4 0.0059 17.0 3.4 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KER22806.1 - 0.011 14.6 3.8 0.014 14.3 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KER22806.1 - 0.021 14.4 0.5 0.024 14.2 0.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KELK PF15796.5 KER22806.1 - 0.025 15.0 5.7 0.06 13.8 5.7 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4349 PF14257.6 KER22806.1 - 0.035 13.5 4.0 0.061 12.8 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GPS2_interact PF15784.5 KER22806.1 - 0.061 13.8 1.5 0.11 12.9 1.5 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF2730 PF10805.8 KER22806.1 - 0.085 13.0 2.9 0.15 12.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Lzipper-MIP1 PF14389.6 KER22806.1 - 0.096 13.0 7.8 0.19 12.0 7.8 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.12 KER22806.1 - 0.47 11.1 3.3 1.1 9.9 2.9 1.8 1 1 0 1 1 1 0 SlyX Latarcin PF10279.9 KER22806.1 - 0.93 9.9 3.8 0.76 10.2 1.4 2.1 2 0 0 2 2 2 0 Latarcin precursor FlaC_arch PF05377.11 KER22806.1 - 1.5 9.3 7.0 7.7 7.0 1.7 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 KER22806.1 - 4.6 7.5 7.5 2.4e+02 2.0 7.5 2.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 KER22806.1 - 4.6 7.6 10.1 2.1 8.8 2.6 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Pyr_redox_2 PF07992.14 KER22807.1 - 1.1e-22 80.6 0.0 1.8e-14 53.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KER22807.1 - 3.5e-06 27.1 0.1 0.087 12.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KER22807.1 - 9.7e-05 21.4 0.1 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 KER22807.1 - 0.00018 21.3 0.3 0.011 15.4 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KER22807.1 - 0.00058 19.0 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KER22807.1 - 0.0048 16.2 0.0 0.03 13.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KER22807.1 - 0.0068 16.9 0.5 0.18 12.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KER22807.1 - 0.016 15.4 0.5 0.045 14.0 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KER22807.1 - 0.074 13.5 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KER22807.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KER22807.1 - 0.13 11.5 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KER22807.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KER22807.1 - 0.16 11.1 0.4 2.5 7.2 0.1 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KER22807.1 - 0.24 10.4 0.0 0.5 9.4 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain LIM PF00412.22 KER22809.1 - 1e-07 32.1 9.7 1e-07 32.1 9.7 1.7 2 0 0 2 2 2 1 LIM domain zf-RING-like PF08746.11 KER22809.1 - 7.2 7.0 13.7 0.79 10.1 0.7 3.0 3 0 0 3 3 3 0 RING-like domain RNA_pol_Rpb4 PF03874.16 KER22810.1 - 4.2e-22 78.8 4.2 5.4e-22 78.4 4.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 EF-G-binding_N PF07299.11 KER22810.1 - 0.068 13.7 0.8 0.19 12.3 0.4 1.9 1 1 0 1 1 1 0 Elongation factor G-binding protein, N-terminal PH PF00169.29 KER22811.1 - 2.2e-14 53.9 0.2 1.9e-08 34.7 0.0 3.4 2 1 0 2 2 2 2 PH domain FERM_C PF09380.10 KER22811.1 - 4.1e-10 39.9 0.0 9.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH_11 PF15413.6 KER22811.1 - 0.01 16.2 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain rve PF00665.26 KER22812.1 - 1.9e-20 73.2 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER22812.1 - 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Synaptobrevin PF00957.21 KER22813.1 - 1.3e-12 47.3 0.6 1.7e-12 46.9 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin MBDa PF16564.5 KER22813.1 - 0.0097 16.1 0.4 0.017 15.3 0.4 1.4 1 0 0 1 1 1 1 p55-binding region of Methyl-CpG-binding domain proteins MBD DUF4736 PF15883.5 KER22813.1 - 0.069 12.9 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) zf-CCHC_3 PF13917.6 KER22814.1 - 0.00016 21.5 0.1 0.00042 20.2 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KER22814.1 - 0.00034 20.4 7.5 0.00034 20.4 7.5 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KER22814.1 - 0.0016 18.3 7.3 0.0016 18.3 7.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER22814.1 - 0.0059 16.4 10.2 0.0059 16.4 10.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KER22814.1 - 0.0099 16.0 10.7 0.021 15.0 10.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCHC PF00098.23 KER22814.1 - 0.015 15.3 3.2 0.015 15.3 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4 PF00097.25 KER22814.1 - 0.022 14.6 9.6 0.048 13.5 9.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER22814.1 - 0.024 15.0 9.5 0.059 13.7 9.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KER22814.1 - 0.042 13.9 7.4 0.1 12.6 7.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 KER22814.1 - 0.79 9.6 5.4 1.8 8.5 5.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-LITAF-like PF10601.9 KER22814.1 - 6.5 7.1 10.3 52 4.2 10.3 2.4 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Ribosomal_L28e PF01778.17 KER22816.1 - 1.7e-31 109.3 0.5 1.7e-31 109.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KER22816.1 - 6.6e-18 65.2 27.6 1.8e-17 63.8 27.6 1.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region Metallophos_2 PF12850.7 KER22817.1 - 4.5e-19 69.2 0.0 6.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KER22817.1 - 0.00021 21.9 0.5 0.091 13.2 0.5 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Filament PF00038.21 KER22818.1 - 0.00017 21.3 49.4 0.0017 18.0 7.7 3.3 1 1 2 3 3 3 3 Intermediate filament protein DUF1664 PF07889.12 KER22818.1 - 0.011 15.8 3.7 0.011 15.8 3.7 4.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 KER22818.1 - 0.013 15.3 2.4 0.013 15.3 2.4 4.2 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.6 KER22818.1 - 0.021 15.2 13.0 0.021 15.2 13.0 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) Utp12 PF04003.12 KER22818.1 - 0.04 14.2 3.8 0.085 13.2 1.5 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family Fez1 PF06818.15 KER22818.1 - 0.14 12.5 53.2 0.7 10.3 16.1 3.3 1 1 2 3 3 3 0 Fez1 DUF4407 PF14362.6 KER22818.1 - 0.21 10.9 38.8 1.9 7.8 3.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 KER22818.1 - 0.92 9.9 37.0 0.14 12.5 3.9 4.5 2 1 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 KER22818.1 - 2.3 8.8 17.6 0.83 10.2 0.1 4.9 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 KER22818.1 - 2.7 8.2 51.8 0.12 12.7 7.0 5.0 1 1 2 4 4 3 0 Flagellar FliJ protein DUF5082 PF16888.5 KER22818.1 - 3.1 8.1 45.3 0.11 12.7 1.4 4.6 2 1 1 4 4 4 0 Domain of unknown function (DUF5082) Myosin_tail_1 PF01576.19 KER22818.1 - 5.1 4.8 58.5 11 3.7 58.5 1.4 1 1 0 1 1 1 0 Myosin tail DUF724 PF05266.14 KER22818.1 - 5.6 6.7 47.7 0.09 12.6 7.0 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF724) SlyX PF04102.12 KER22818.1 - 6.6 7.4 41.2 4.3 8.0 0.7 7.2 3 1 3 6 6 6 0 SlyX ADIP PF11559.8 KER22818.1 - 8.3 6.5 57.9 0.089 12.9 12.9 4.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 KER22818.1 - 8.3 6.1 52.2 0.41 10.4 13.2 4.1 1 1 2 3 3 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CALCOCO1 PF07888.11 KER22818.1 - 9.6 4.9 56.3 0.0058 15.5 26.7 2.7 1 1 1 2 2 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RAI16-like PF10257.9 KER22819.1 - 3e-53 181.0 6.7 5.6e-53 180.1 6.7 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF5113 PF17140.4 KER22819.1 - 0.19 11.5 0.1 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Nrap_D4 PF17405.2 KER22820.1 - 2.3e-27 95.7 0.0 4.5e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KER22820.1 - 4.4e-21 75.3 0.0 1.3e-17 64.1 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 KER22820.1 - 1.5e-17 64.1 0.0 4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KER22820.1 - 4.9e-05 23.6 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 KER22820.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain SNF2_N PF00176.23 KER22824.1 - 2.8e-47 161.2 0.0 4.3e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER22824.1 - 1.2e-14 54.6 0.0 2.3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER22824.1 - 9.4e-08 32.2 0.0 2.1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KER22824.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KER22824.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2075 PF09848.9 KER22824.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.15 KER22824.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 RWD PF05773.22 KER22825.1 - 6e-06 26.5 0.0 1.3e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 RWD domain zf-RING_11 PF17123.5 KER22825.1 - 0.0078 15.9 7.2 0.0078 15.9 7.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 KER22825.1 - 0.014 15.7 12.0 0.089 13.1 12.1 2.0 1 1 0 1 1 1 0 Ring finger domain RINGv PF12906.7 KER22825.1 - 0.085 13.0 4.4 0.27 11.4 4.5 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.6 KER22825.1 - 3 7.9 11.4 18 5.4 11.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 KER22825.1 - 6.1 7.1 8.2 4.8 7.4 5.6 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain Aph-1 PF06105.12 KER22826.1 - 2.9e-61 206.8 11.6 3.5e-61 206.5 11.6 1.0 1 0 0 1 1 1 1 Aph-1 protein MAPEG PF01124.18 KER22827.1 - 1.7e-17 63.6 0.7 2.3e-17 63.1 0.7 1.2 1 0 0 1 1 1 1 MAPEG family Cadherin PF00028.17 KER22829.1 - 1.7e-12 47.6 0.0 9.1e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Cadherin domain Comm PF15957.5 KER22829.1 - 0.04 14.2 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 Commissureless DAP10 PF07213.11 KER22829.1 - 0.13 12.3 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Cadherin PF00028.17 KER22830.1 - 3.6e-62 206.8 6.5 6.5e-14 52.1 0.2 7.8 7 0 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER22830.1 - 9.2e-11 41.4 0.2 2e-07 30.7 0.0 4.4 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 KER22830.1 - 0.0071 16.3 7.4 7.5 6.6 0.0 5.1 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 KER22830.1 - 0.0094 16.2 0.0 0.52 10.6 0.0 3.4 4 0 0 4 4 4 1 RET Cadherin like domain 1 Cadherin_4 PF17803.1 KER22830.1 - 0.21 12.2 0.0 0.21 12.2 0.0 4.8 4 0 0 4 4 4 0 Bacterial cadherin-like domain Ank_2 PF12796.7 KER22832.1 - 3.4e-134 437.8 45.7 7.6e-20 71.3 0.1 11.7 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.30 KER22832.1 - 9.6e-124 399.0 65.1 8.9e-07 29.1 0.2 22.5 21 1 1 22 22 22 20 Ankyrin repeat Ank_4 PF13637.6 KER22832.1 - 6.8e-112 364.5 40.7 3.5e-13 49.8 0.1 15.9 6 4 12 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER22832.1 - 6.4e-103 324.2 37.6 4.3e-06 26.7 0.1 22.5 22 0 0 22 22 22 19 Ankyrin repeat Ank_5 PF13857.6 KER22832.1 - 4.9e-101 329.5 49.4 7.4e-09 35.7 0.1 17.3 4 3 13 18 18 18 16 Ankyrin repeats (many copies) ZU5 PF00791.20 KER22832.1 - 8.4e-29 99.8 1.4 1.1e-20 73.8 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain UPA_2 PF17809.1 KER22832.1 - 1.3e-25 89.7 0.0 4e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 UPA domain Death PF00531.22 KER22832.1 - 1.1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Death domain K1 PF02960.14 KER22832.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 K1 glycoprotein DSPc PF00782.20 KER22835.1 - 6.3e-17 61.6 0.0 8.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KER22835.1 - 5e-07 29.4 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KER22835.1 - 2.7e-05 24.3 0.0 3.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KER22835.1 - 6.2e-05 22.7 0.0 7.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KER22835.1 - 0.011 15.4 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KER22835.1 - 0.038 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PARG_cat PF05028.14 KER22836.1 - 1.2e-117 393.0 0.0 1.6e-117 392.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) RRM_1 PF00076.22 KER22837.1 - 4.6e-25 87.2 0.0 5.6e-12 45.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER22837.1 - 0.081 13.1 0.0 2.1 8.5 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Trnau1ap PF17654.1 KER22837.1 - 0.58 11.1 5.4 0.48 11.3 3.6 1.8 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins zf-RING_2 PF13639.6 KER22838.1 - 1.5e-06 28.4 9.8 4.3e-06 27.0 9.8 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KER22838.1 - 0.0011 19.1 4.8 0.003 17.7 4.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KER22838.1 - 0.0012 19.1 7.6 0.0031 17.8 7.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KER22838.1 - 0.0083 16.2 3.5 0.025 14.6 3.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KER22838.1 - 0.013 15.6 6.3 0.034 14.3 6.3 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KER22838.1 - 0.05 13.5 9.8 0.14 12.1 9.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KER22838.1 - 0.055 13.4 5.2 0.14 12.0 5.2 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KER22838.1 - 0.059 13.0 7.1 0.17 11.5 7.1 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KER22838.1 - 0.19 11.7 7.1 0.39 10.6 7.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KER22838.1 - 1.7 9.0 8.7 3.8 7.9 8.7 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 KER22838.1 - 3.3 7.6 8.0 7.2 6.5 8.0 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PNRC PF15365.6 KER22838.1 - 3.7 7.5 6.8 12 5.9 6.8 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif zf-C3HC4_3 PF13920.6 KER22838.1 - 7 6.6 8.7 19 5.2 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KER22839.1 - 8.1e-24 84.4 0.0 1.4e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22839.1 - 6.2e-15 55.2 0.0 4.4e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER22839.1 - 2e-09 36.8 0.2 2.6e-09 36.4 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase SBF2 PF12335.8 KER22841.1 - 8.3e-13 48.5 0.2 1.6e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Myotubularin protein PPP4R2 PF09184.11 KER22841.1 - 3 7.3 11.9 5.1 6.6 11.9 1.5 1 0 0 1 1 1 0 PPP4R2 C2 PF00168.30 KER22843.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 KER22843.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 GPS2_interact PF15784.5 KER22843.1 - 1.2 9.6 5.1 1.4 9.4 0.6 3.3 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain FliS PF02561.14 KER22843.1 - 6.2 7.1 6.2 9.2 6.6 0.2 3.3 3 0 0 3 3 3 0 Flagellar protein FliS EAP30 PF04157.16 KER22844.1 - 1.1e-62 211.4 0.0 1.4e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 KER22844.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus GSH_synth_ATP PF03917.17 KER22844.1 - 0.17 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain BAH PF01426.18 KER22847.1 - 1.2e-23 83.3 0.1 3.2e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 BAH domain Myb_DNA-binding PF00249.31 KER22847.1 - 8.1e-05 22.7 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain GATA PF00320.27 KER22847.1 - 0.00099 18.7 2.7 0.0028 17.2 2.7 1.8 1 0 0 1 1 1 1 GATA zinc finger ELM2 PF01448.24 KER22847.1 - 0.0016 19.2 0.1 0.0065 17.2 0.1 2.1 1 0 0 1 1 1 1 ELM2 domain MTA_R1 PF17226.2 KER22847.1 - 0.018 15.2 0.6 0.018 15.2 0.6 3.0 3 0 0 3 3 3 0 MTA R1 domain DUF5578 PF17741.1 KER22847.1 - 0.21 11.0 0.2 0.35 10.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5578) NCD1 PF04904.13 KER22849.1 - 0.0047 16.9 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) JmjC PF02373.22 KER22852.1 - 3.7e-08 33.8 0.0 8.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase GLTT PF01744.20 KER22852.1 - 0.23 11.2 4.7 11 5.8 0.4 3.0 2 0 0 2 2 2 0 GLTT repeat (6 copies) zf-C5HC2 PF02928.16 KER22852.1 - 4.6 7.7 10.3 12 6.4 10.3 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger zf-UBP PF02148.19 KER22852.1 - 7.1 7.0 10.6 12 6.3 9.5 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein C1_2 PF03107.16 KER22852.1 - 9.2 6.7 12.6 0.39 11.1 6.2 2.0 2 0 0 2 2 2 0 C1 domain Ras PF00071.22 KER22856.1 - 1.2e-57 194.1 0.0 1.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER22856.1 - 5.1e-25 88.0 0.0 7.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER22856.1 - 1.5e-11 44.1 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER22856.1 - 2.1e-05 24.1 0.1 3.5e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER22856.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KER22856.1 - 0.0037 16.7 0.0 0.0062 16.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KER22856.1 - 0.021 14.7 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 KER22856.1 - 0.05 12.6 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ldh_1_N PF00056.23 KER22856.1 - 0.089 12.9 0.1 2 8.5 0.1 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Bromodomain PF00439.25 KER22857.1 - 1.1e-16 60.6 0.0 2.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Med9 PF07544.13 KER22857.1 - 0.0042 17.1 5.2 1 9.5 0.2 3.1 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DASH_Duo1 PF08651.10 KER22857.1 - 0.036 13.9 0.3 17 5.3 0.0 3.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 Fis1_TPR_N PF14852.6 KER22857.1 - 0.25 11.0 1.9 19 5.0 0.1 2.5 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat Annexin PF00191.20 KER22860.1 - 6.4e-62 205.5 4.0 8.7e-20 70.6 0.4 4.9 4 1 0 4 4 4 4 Annexin SHQ1 PF04925.15 KER22860.1 - 0.089 12.3 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 SHQ1 protein AAA_26 PF13500.6 KER22860.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Acetyltransf_11 PF13720.6 KER22860.1 - 0.21 12.1 1.1 36 4.9 0.0 3.8 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Annexin PF00191.20 KER22861.1 - 7.4e-08 32.3 1.7 0.014 15.4 0.1 2.7 2 0 0 2 2 2 2 Annexin DUF1244 PF06844.11 KER22861.1 - 0.48 10.6 3.1 31 4.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1244) Annexin PF00191.20 KER22863.1 - 6.5e-12 45.3 1.1 1.5e-08 34.6 0.2 2.9 3 0 0 3 3 3 2 Annexin DUF4384 PF14326.6 KER22866.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Dynactin_p62 PF05502.13 KER22867.1 - 9.1e-34 117.1 20.8 1.9e-20 73.1 10.6 2.3 2 0 0 2 2 2 2 Dynactin p62 family EMG1 PF03587.14 KER22869.1 - 7.2e-73 244.4 0.0 8.8e-73 244.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase HECT PF00632.25 KER22870.1 - 7.7e-96 321.2 0.2 1.2e-95 320.5 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KER22870.1 - 6e-44 147.8 20.8 1.3e-12 47.6 1.9 4.8 5 0 0 5 5 5 4 WW domain MBD PF01429.19 KER22870.1 - 0.23 11.2 6.3 8.4 6.2 0.1 4.5 5 0 0 5 5 5 0 Methyl-CpG binding domain WW PF00397.26 KER22871.1 - 4.1e-09 36.4 0.1 9.3e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 WW domain Pollen_Ole_e_I PF01190.17 KER22871.1 - 0.17 12.3 4.0 1.5 9.2 0.2 2.8 2 0 0 2 2 2 0 Pollen proteins Ole e I like WD40 PF00400.32 KER22872.1 - 4.4e-20 71.6 25.6 6.9e-07 29.9 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.11 KER22872.1 - 8.2e-18 64.9 0.0 4.1e-16 59.4 0.0 2.7 2 0 0 2 2 2 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 KER22872.1 - 1.9e-07 31.3 2.5 3.7 7.9 0.0 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KER22872.1 - 0.0069 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif CYTH PF01928.21 KER22872.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 2 0 0 2 2 2 0 CYTH domain Sirohm_synth_M PF14824.6 KER22872.1 - 0.22 11.0 3.1 12 5.4 0.2 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central WD40_like PF17005.5 KER22872.1 - 0.24 10.7 0.0 20 4.4 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Prok-RING_2 PF14445.6 KER22872.1 - 0.49 10.6 2.9 5.4 7.3 1.3 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 GDNF PF02351.16 KER22877.1 - 5.6e-08 33.6 66.7 0.025 15.5 15.2 5.4 4 1 0 4 4 4 4 GDNF/GAS1 domain Pex14_N PF04695.13 KER22877.1 - 6.8 7.3 8.1 1.3 9.7 2.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RVT_1 PF00078.27 KER22880.1 - 5.8e-06 26.0 0.1 6.7e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb1_R PF05001.13 KER22881.1 - 0.48 10.9 4.0 1.2 9.7 4.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat PBP PF01161.20 KER22882.1 - 2.6e-09 37.5 0.0 4.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPR_2 PF07719.17 KER22883.1 - 3.8e-32 107.8 14.4 7.9e-07 28.7 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KER22883.1 - 4.1e-32 108.7 14.1 1.9e-07 30.6 1.5 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat DnaJ PF00226.31 KER22883.1 - 1.4e-26 92.4 7.6 2.2e-25 88.6 4.6 2.8 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 KER22883.1 - 2.7e-21 75.0 3.3 6.7e-07 28.9 1.6 5.8 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.6 KER22883.1 - 1.1e-16 59.6 7.4 0.00033 20.6 0.4 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KER22883.1 - 4.4e-13 49.5 4.7 3.6e-06 27.4 0.0 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER22883.1 - 5.8e-13 48.2 11.2 0.0073 16.6 0.1 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KER22883.1 - 9.6e-11 42.2 9.1 6.7e-05 23.5 0.0 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KER22883.1 - 2.3e-10 40.4 1.8 0.0029 18.1 0.0 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER22883.1 - 5.9e-10 39.3 15.6 5.7e-06 26.5 2.2 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KER22883.1 - 6e-09 35.9 6.0 0.0016 18.6 0.7 4.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER22883.1 - 1.5e-08 34.7 6.9 0.084 13.7 0.0 6.1 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER22883.1 - 8e-07 28.7 9.6 8 6.7 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER22883.1 - 3.6e-05 23.9 17.3 0.0035 17.5 4.4 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 KER22883.1 - 0.00011 22.2 4.8 0.03 14.3 0.2 3.0 1 1 1 2 2 2 2 Putative TPR-like repeat NYD-SP12_N PF15015.6 KER22883.1 - 0.00043 18.8 0.1 0.00068 18.1 0.1 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal DUF3856 PF12968.7 KER22883.1 - 0.00058 20.0 7.6 0.26 11.3 0.3 4.7 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 KER22883.1 - 0.086 12.9 11.5 0.36 10.9 0.2 5.1 6 1 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KER22883.1 - 0.14 12.5 1.9 0.95 9.8 0.1 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KER22883.1 - 0.29 11.2 21.4 4.3 7.5 0.1 6.4 5 1 2 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KER22883.1 - 0.34 10.8 9.7 28 4.8 1.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 KER22883.1 - 0.47 10.9 5.1 6.3 7.2 0.6 3.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain HTH_Bact PF18768.1 KER22883.1 - 1.6 8.4 7.2 16 5.1 0.0 5.0 5 1 0 5 5 5 0 Helix-turn-helix bacterial domain TPR_3 PF07720.12 KER22883.1 - 6.9 6.8 8.5 18 5.4 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 KER22883.1 - 7 6.0 9.0 4.7 6.6 0.4 3.3 2 1 2 4 4 4 0 Meiosis protein SPO22/ZIP4 like Peptidase_M8 PF01457.16 KER22884.1 - 1.2e-54 186.0 0.0 1e-53 182.8 0.0 2.0 1 1 0 1 1 1 1 Leishmanolysin DUF2883 PF11097.8 KER22884.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Ras PF00071.22 KER22885.1 - 1.3e-05 24.9 0.0 0.0084 15.7 0.0 2.3 2 0 0 2 2 2 2 Ras family zf-C2H2_jaz PF12171.8 KER22886.1 - 0.018 15.4 13.0 0.6 10.5 0.6 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHC2 PF01807.20 KER22886.1 - 0.12 12.2 4.5 0.68 9.8 0.8 2.7 2 0 0 2 2 2 0 CHC2 zinc finger FYVE_2 PF02318.16 KER22886.1 - 1.1 9.4 11.5 1.8 8.8 3.9 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger zf-H2C2_2 PF13465.6 KER22887.1 - 3.2e-24 84.2 47.7 1.1e-07 31.9 1.1 7.8 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER22887.1 - 8.5e-21 73.2 55.0 2e-05 24.8 0.5 8.0 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER22887.1 - 5.7e-13 48.5 56.1 0.0026 18.4 0.5 7.7 8 0 0 8 8 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER22887.1 - 1.1e-10 41.5 19.3 0.016 15.5 0.1 6.2 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KER22887.1 - 4.9e-07 29.4 34.7 0.011 15.5 0.3 7.2 7 1 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KER22887.1 - 0.00031 21.1 18.7 1.6 9.2 0.1 5.6 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KER22887.1 - 0.0026 17.5 0.2 0.0026 17.5 0.2 5.6 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KER22887.1 - 0.0094 16.3 22.9 0.99 9.8 0.5 5.1 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KER22887.1 - 0.011 16.1 6.7 0.053 13.9 1.2 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 KER22887.1 - 0.11 13.0 0.1 0.11 13.0 0.1 4.8 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 KER22887.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.8 2 1 2 5 5 4 0 GAGA factor zf-C2H2_6 PF13912.6 KER22887.1 - 1 9.4 34.2 0.62 10.1 1.4 6.0 6 0 0 6 6 5 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KER22887.1 - 2.5 8.0 12.5 1.4 8.8 0.1 4.7 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) TerY_C PF15616.6 KER22887.1 - 5 7.3 15.7 9.9 6.3 2.0 3.3 2 1 1 3 3 3 0 TerY-C metal binding domain zf-Di19 PF05605.12 KER22887.1 - 9.6 6.6 32.3 0.12 12.7 0.8 4.2 3 2 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding DUF1609 PF07753.11 KER22889.1 - 0.22 11.0 0.2 0.36 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) UQ_con PF00179.26 KER22891.1 - 1.6e-45 154.2 0.0 2.3e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER22891.1 - 0.00032 20.4 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KER22891.1 - 0.00047 20.0 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KER22891.1 - 0.054 13.8 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Pkinase PF00069.25 KER22892.1 - 2.2e-76 256.7 0.0 2.7e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER22892.1 - 1.1e-33 116.6 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER22892.1 - 7.6e-07 28.7 0.0 3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KER22892.1 - 5.8e-05 23.1 0.0 0.007 16.3 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER22892.1 - 0.00094 18.2 0.1 0.0026 16.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER22892.1 - 0.001 18.5 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER22892.1 - 0.0037 16.1 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PUF PF00806.19 KER22892.1 - 0.0072 16.0 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat RIO1 PF01163.22 KER22892.1 - 0.022 14.4 0.1 0.064 12.9 0.0 1.8 2 1 0 2 2 2 0 RIO1 family RNase_T PF00929.24 KER22893.1 - 3.7e-13 50.4 0.0 7.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Methyltransf_32 PF13679.6 KER22893.1 - 5.7e-09 36.2 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KER22893.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KER22893.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.11 KER22895.1 - 3.4e-07 30.8 2.3 7.8e-07 29.6 0.1 2.6 3 1 0 3 3 3 1 SNARE associated Golgi protein GP41 PF00517.17 KER22895.1 - 0.016 15.1 0.3 0.026 14.4 0.3 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Clat_adaptor_s PF01217.20 KER22896.1 - 1.1e-49 168.0 2.7 1.5e-49 167.6 2.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_14 PF17978.1 KER22897.1 - 1.3e-23 83.2 1.6 1.3e-23 83.2 1.6 3.2 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain DZR PF12773.7 KER22897.1 - 1.9e-14 53.4 49.0 1.4e-08 34.6 7.7 8.0 4 3 3 8 8 5 4 Double zinc ribbon Ank_2 PF12796.7 KER22897.1 - 8.6e-11 42.3 0.0 3.1e-10 40.5 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) CHB_HEX_C_1 PF13290.6 KER22897.1 - 9.4e-10 38.4 0.6 1.9e-09 37.4 0.6 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_3 PF13606.6 KER22897.1 - 3.9e-09 36.0 0.1 0.0054 17.1 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 KER22897.1 - 5.3e-09 36.1 2.9 0.0061 17.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Fn3_assoc PF13287.6 KER22897.1 - 1.1e-08 35.1 0.2 2.3e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Fn3 associated Ank_4 PF13637.6 KER22897.1 - 3.9e-08 33.7 0.0 5.7e-05 23.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER22897.1 - 1.3e-07 31.7 0.1 1.6e-06 28.3 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) IBR PF01485.21 KER22897.1 - 2.7e-06 27.5 13.0 2.7e-06 27.5 13.0 8.2 6 3 0 6 6 2 2 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KER22897.1 - 9.6e-06 25.2 11.9 0.0002 20.9 4.1 9.3 9 0 0 9 9 9 3 zinc-ribbon domain Rad60-SLD PF11976.8 KER22897.1 - 0.0024 17.6 0.1 0.0047 16.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KER22897.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zinc_ribbon_15 PF17032.5 KER22897.1 - 0.3 11.8 0.1 0.3 11.8 0.1 8.0 5 2 2 7 7 6 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KER22897.1 - 1.5 8.3 59.8 0.042 13.3 1.2 8.9 8 2 1 9 9 9 0 zinc-ribbon domain Band_7 PF01145.25 KER22898.1 - 1.3e-32 113.2 2.7 1.7e-32 112.9 2.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER22898.1 - 0.001 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Branch PF02485.21 KER22899.1 - 9.2e-20 71.2 0.0 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme HECW1_helix PF18436.1 KER22899.1 - 0.12 12.5 1.2 7.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 zf-C3HC4_2 PF13923.6 KER22900.1 - 1.1e-10 41.2 8.4 1.1e-10 41.2 8.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER22900.1 - 7.3e-09 35.4 8.4 1.7e-08 34.2 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER22900.1 - 3.1e-08 33.3 10.1 6.3e-08 32.4 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER22900.1 - 8.5e-08 32.4 7.7 8.5e-08 32.4 7.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KER22900.1 - 4.3e-07 29.8 11.0 1.3e-06 28.4 11.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KER22900.1 - 5.4e-07 29.4 9.8 1.2e-06 28.3 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KER22900.1 - 1.4e-06 28.3 10.6 3.6e-06 27.0 10.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KER22900.1 - 4.7e-06 26.4 10.7 4.7e-06 26.4 10.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KER22900.1 - 0.0042 16.9 4.8 0.0078 16.1 4.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KER22900.1 - 0.19 11.6 7.1 0.51 10.2 7.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KER22900.1 - 0.29 11.5 11.1 0.076 13.3 6.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KER22900.1 - 0.36 11.0 7.8 0.81 9.9 7.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KER22900.1 - 1.9 8.4 6.9 3.7 7.4 6.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GKAP PF03359.13 KER22901.1 - 4.7e-24 85.6 13.9 6.5e-24 85.1 12.0 2.1 1 1 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein FAM176 PF14851.6 KER22903.1 - 0.66 9.6 3.9 0.27 10.9 1.2 1.7 2 0 0 2 2 2 0 FAM176 family Clathrin_propel PF01394.20 KER22904.1 - 8.4e-45 149.0 3.3 1.5e-09 37.6 0.0 6.3 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KER22904.1 - 1.3e-32 111.5 0.7 2.2e-32 110.7 0.7 1.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KER22904.1 - 2.1e-09 36.6 0.2 4.4e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_19 PF14559.6 KER22904.1 - 0.0038 17.7 0.3 1.4 9.5 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat RVT_1 PF00078.27 KER22905.1 - 0.0055 16.3 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_1 PF00018.28 KER22906.1 - 1.4e-44 149.5 1.5 1.8e-15 56.3 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KER22906.1 - 4.5e-41 138.5 1.8 5.2e-14 51.8 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KER22906.1 - 1.5e-32 111.1 0.1 5.7e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 KER22906.1 - 4.3e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain rve PF00665.26 KER22906.1 - 2.6e-13 50.2 0.0 4.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain SH3_3 PF08239.11 KER22906.1 - 5.3e-10 39.4 5.8 4e-05 23.8 0.2 3.7 4 0 0 4 4 4 3 Bacterial SH3 domain SH3_10 PF17902.1 KER22906.1 - 1.9e-07 31.1 0.1 0.00016 21.7 0.0 3.4 3 0 0 3 3 3 1 SH3 domain hSH3 PF14603.6 KER22906.1 - 5.7e-07 29.9 0.0 0.045 14.2 0.0 3.2 3 0 0 3 3 3 2 Helically-extended SH3 domain SH3_4 PF06347.13 KER22906.1 - 0.011 15.5 1.3 0.15 11.9 0.1 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain rve_3 PF13683.6 KER22906.1 - 0.032 14.0 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain SH3_16 PF18348.1 KER22906.1 - 0.31 10.9 1.2 4.2 7.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain FERM_M PF00373.18 KER22907.1 - 8.2e-13 48.8 0.2 1.4e-12 48.1 0.2 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KER22907.1 - 1.5e-07 31.2 0.3 3.9e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 KER22907.1 - 6.7e-07 29.6 0.2 1.3e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DUF4954 PF16314.5 KER22907.1 - 0.098 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Mon2_C PF16206.5 KER22908.1 - 2e-121 406.6 3.4 6.4e-58 196.6 0.8 3.5 2 1 1 3 3 3 3 C-terminal region of Mon2 protein Sec7_N PF12783.7 KER22908.1 - 2.9e-40 137.8 2.9 1.4e-39 135.6 0.7 3.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KER22908.1 - 4.9e-26 91.5 9.9 4e-24 85.2 2.0 4.0 3 1 1 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 KER22908.1 - 1.5e-08 34.3 0.4 2.9e-07 30.2 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 7TM_GPCR_Srw PF10324.9 KER22909.1 - 3e-27 95.8 9.1 2.1e-19 70.0 0.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER22909.1 - 6.5e-09 35.5 4.7 1.2e-06 28.0 4.7 2.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mucin PF01456.17 KER22909.1 - 0.00027 21.0 2.2 0.031 14.3 0.1 2.6 2 0 0 2 2 2 2 Mucin-like glycoprotein tRNA-synt_1b PF00579.25 KER22911.1 - 7.7e-20 71.4 0.0 1.6e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4566 PF15130.6 KER22911.1 - 0.12 11.8 0.5 0.77 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) SH3_1 PF00018.28 KER22913.1 - 1.9e-37 126.6 0.4 3.9e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KER22913.1 - 1.3e-33 114.6 0.9 5.1e-13 48.7 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KER22913.1 - 5.4e-30 102.8 0.1 2e-11 43.4 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 KER22913.1 - 1.4e-11 44.4 0.1 5.3e-11 42.5 0.0 2.1 3 0 0 3 3 3 1 SH2 domain SH3_3 PF08239.11 KER22913.1 - 6.9e-10 39.1 1.4 3e-05 24.2 0.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_16 PF18348.1 KER22913.1 - 5.5e-05 22.9 0.3 0.77 9.6 0.0 3.5 3 0 0 3 3 3 1 Bacterial dipeptidyl-peptidase Sh3 domain SH3_4 PF06347.13 KER22913.1 - 0.0002 21.1 0.2 0.06 13.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_10 PF17902.1 KER22913.1 - 0.00025 21.0 0.1 0.0036 17.3 0.0 2.7 3 0 0 3 3 3 1 SH3 domain hSH3 PF14603.6 KER22913.1 - 0.013 15.9 0.0 4.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Helically-extended SH3 domain SH2_2 PF14633.6 KER22913.1 - 0.16 11.3 0.0 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 SH2 domain Herpes_UL33 PF03581.13 KER22914.1 - 0.093 13.1 0.2 12 6.4 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus UL33-like protein DAGK_cat PF00781.24 KER22914.1 - 0.14 11.8 0.5 10 5.7 0.0 2.2 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain Phage_holin_3_1 PF05106.12 KER22914.1 - 0.33 11.4 1.1 18 5.8 0.1 2.2 1 1 1 2 2 2 0 Phage holin family (Lysis protein S) Sec23_trunk PF04811.15 KER22915.1 - 1.7e-56 191.6 0.0 2.8e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KER22915.1 - 1.1e-19 70.2 0.0 2.6e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KER22915.1 - 1.4e-19 70.6 0.1 3.7e-19 69.2 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KER22915.1 - 9.8e-16 57.5 3.1 2.4e-15 56.3 3.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KER22915.1 - 0.024 14.0 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EF-hand_7 PF13499.6 KER22916.1 - 1.1e-07 32.2 2.2 2.8e-07 30.9 1.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KER22916.1 - 1.3e-05 24.9 1.1 5.6e-05 22.9 0.5 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER22916.1 - 1.4e-05 24.6 1.6 0.14 12.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER22916.1 - 0.00029 20.2 0.7 0.35 10.5 0.1 2.7 2 0 0 2 2 2 2 EF hand Rav1p_C PF12234.8 KER22916.1 - 0.0076 14.7 0.1 0.0082 14.6 0.1 1.0 1 0 0 1 1 1 1 RAVE protein 1 C terminal FAM180 PF15173.6 KER22916.1 - 0.023 14.7 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 FAM180 family Rootletin PF15035.6 KER22916.1 - 0.051 13.6 0.2 0.075 13.0 0.2 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Ras PF00071.22 KER22917.1 - 7.3e-18 64.7 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER22917.1 - 2.1e-07 31.2 0.1 4.9e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER22917.1 - 1.4e-06 27.9 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Phage_GP20 PF06810.11 KER22917.1 - 0.012 15.4 5.4 0.022 14.6 5.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Med2 PF11214.8 KER22917.1 - 0.037 14.2 2.7 0.073 13.2 2.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Golgin_A5 PF09787.9 KER22917.1 - 0.058 12.9 9.8 0.099 12.1 9.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Macoilin PF09726.9 KER22917.1 - 0.16 10.5 6.3 0.22 10.0 6.3 1.1 1 0 0 1 1 1 0 Macoilin family CENP-Q PF13094.6 KER22917.1 - 0.19 11.9 8.7 0.37 11.0 8.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.8 KER22917.1 - 0.19 11.0 9.7 0.29 10.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 KER22917.1 - 0.76 9.8 2.6 1.8 8.6 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GrpE PF01025.19 KER22917.1 - 1.2 8.8 5.6 2.2 7.9 5.6 1.4 1 0 0 1 1 1 0 GrpE FapA PF03961.13 KER22917.1 - 1.4 7.4 5.6 2 6.9 5.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sod_Cu PF00080.20 KER22918.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.3 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) UPF0220 PF05255.11 KER22920.1 - 1.6e-28 99.3 1.2 1.8e-28 99.2 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TMEM43 PF07787.12 KER22920.1 - 0.14 11.5 1.7 0.2 11.0 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 IKI3 PF04762.12 KER22921.1 - 8.1e-133 444.4 0.0 5.4e-92 309.3 0.0 4.2 2 2 0 2 2 2 2 IKI3 family TPR_16 PF13432.6 KER22921.1 - 0.054 14.1 2.3 0.59 10.8 1.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TLD PF07534.16 KER22922.1 - 3.5e-16 59.7 0.0 5.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 KER22922.1 - 1.3e-07 31.5 0.0 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Exo_endo_phos_2 PF14529.6 KER22924.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER22924.1 - 0.086 12.3 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Xpo1 PF08389.12 KER22925.1 - 2.5e-08 34.1 5.3 3.6e-08 33.6 0.7 3.7 4 1 1 5 5 5 1 Exportin 1-like protein Glyco_trans_2_3 PF13632.6 KER22926.1 - 0.00093 19.2 1.2 0.00093 19.2 1.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MARVEL PF01284.23 KER22926.1 - 0.0028 17.7 25.0 0.019 15.0 25.0 2.0 1 1 0 1 1 1 1 Membrane-associating domain TIM21 PF08294.11 KER22928.1 - 7.1e-35 120.0 0.1 8.7e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KER22928.1 - 3.2e-06 26.9 0.0 9.6e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF5560 PF17715.1 KER22929.1 - 0.076 12.5 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) CDI PF02234.19 KER22929.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor PRP38_assoc PF12871.7 KER22930.1 - 4.6 7.9 11.9 0.21 12.2 5.2 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Proteasome PF00227.26 KER22931.1 - 6.3e-60 201.9 0.3 9e-60 201.4 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KER22931.1 - 1.3e-14 53.5 0.2 2.9e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPR_2 PF07719.17 KER22932.1 - 6.6e-09 35.2 9.6 0.41 10.9 0.4 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KER22932.1 - 8.1e-09 35.7 0.5 0.00043 20.5 0.1 4.5 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KER22932.1 - 3.2e-05 24.4 17.9 1.3 10.1 0.1 8.0 8 1 0 8 8 6 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KER22932.1 - 0.00015 21.0 2.2 0.072 12.1 0.0 3.5 3 0 0 3 3 3 1 Coatomer WD associated region PPR PF01535.20 KER22932.1 - 0.00034 20.7 1.4 5.3 7.5 0.2 5.9 7 0 0 7 7 6 1 PPR repeat Clathrin PF00637.20 KER22932.1 - 0.0011 18.8 2.9 27 4.6 0.0 4.9 3 1 2 5 5 5 0 Region in Clathrin and VPS PALB2_WD40 PF16756.5 KER22932.1 - 0.0016 17.4 0.2 0.003 16.5 0.2 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain TPR_19 PF14559.6 KER22932.1 - 0.0024 18.3 10.0 1.3 9.6 1.2 6.0 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER22932.1 - 0.018 15.0 11.4 40 4.6 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Nic96 PF04097.14 KER22932.1 - 0.027 12.9 1.7 2.8 6.3 0.1 3.3 2 1 1 3 3 3 0 Nup93/Nic96 PPR_2 PF13041.6 KER22932.1 - 0.033 14.4 3.2 0.34 11.2 0.2 3.7 3 0 0 3 3 3 0 PPR repeat family TPR_4 PF07721.14 KER22932.1 - 0.066 13.9 9.6 4.1 8.3 0.1 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.32 KER22932.1 - 0.095 13.6 3.6 72 4.5 0.8 4.4 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_12 PF13424.6 KER22932.1 - 0.13 12.6 19.5 3.4 8.0 0.2 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KER22932.1 - 0.17 11.6 4.1 0.91 9.2 0.2 3.6 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 KER22932.1 - 2.1 8.0 5.3 27 4.4 0.0 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KER22932.1 - 3.2 8.2 12.4 12 6.4 0.6 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 KER22932.1 - 8.9 6.5 11.9 4.7 7.4 0.1 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Suf PF05843.14 KER22933.1 - 2e-76 257.8 0.0 8.7e-71 239.3 0.0 4.3 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) RVT_1 PF00078.27 KER22933.1 - 1.9e-13 50.5 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNAP PF14938.6 KER22933.1 - 0.0025 17.3 0.8 0.042 13.3 0.2 2.2 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP PRP38 PF03371.15 KER22934.1 - 2.1e-59 200.3 0.4 2.8e-59 199.9 0.4 1.2 1 0 0 1 1 1 1 PRP38 family Aminotran_5 PF00266.19 KER22935.1 - 1e-08 34.6 0.0 1.2e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.19 KER22936.1 - 4.9e-79 266.0 0.0 7.2e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V RVT_1 PF00078.27 KER22936.1 - 2.6e-25 89.2 0.0 2.5e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Beta_elim_lyase PF01212.21 KER22936.1 - 2.9e-08 33.4 0.0 4.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KER22936.1 - 4.6e-06 26.2 0.1 7.7e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KER22936.1 - 0.0097 14.5 0.1 0.019 13.5 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KER22936.1 - 0.029 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DOMON PF03351.17 KER22937.1 - 9.1e-10 38.8 0.0 1.6e-08 34.8 0.0 2.1 1 1 1 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 KER22937.1 - 6.9e-08 32.7 6.2 6.9e-08 32.7 6.2 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF4381 PF14316.6 KER22937.1 - 0.18 12.1 0.1 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) YdjO PF14169.6 KER22938.1 - 0.12 12.1 1.5 0.2 11.4 0.2 2.0 3 0 0 3 3 3 0 Cold-inducible protein YdjO GIY-YIG PF01541.24 KER22939.1 - 0.042 14.1 0.0 0.063 13.6 0.0 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain LRR_8 PF13855.6 KER22940.1 - 9e-08 31.8 4.3 0.0014 18.3 0.1 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KER22940.1 - 9e-05 22.8 2.8 0.32 11.5 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 KER22940.1 - 0.00019 22.3 0.1 0.0004 21.2 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KER22940.1 - 0.0006 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 KER22940.1 - 0.0025 17.7 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Rifin ECSCR PF15820.5 KER22940.1 - 0.0043 16.8 0.1 0.0099 15.7 0.1 1.6 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator Baculo_11_kDa PF06143.11 KER22940.1 - 0.011 15.2 0.3 0.025 14.1 0.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.6 KER22940.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LRRC37AB_C PF14914.6 KER22940.1 - 0.03 14.2 0.0 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Syndecan PF01034.20 KER22940.1 - 0.036 14.0 0.2 0.078 12.9 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 KER22940.1 - 0.039 14.2 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF1180 PF06679.12 KER22940.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cadherin_C_2 PF16492.5 KER22940.1 - 0.092 13.5 0.1 0.27 12.0 0.0 1.8 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal DUF3377 PF11857.8 KER22940.1 - 0.11 12.5 0.7 0.21 11.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3634 PF12321.8 KER22940.1 - 0.11 12.9 0.3 0.23 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) ASFV_J13L PF05568.11 KER22940.1 - 0.13 12.0 2.9 0.17 11.6 2.4 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein MAP17 PF15807.5 KER22940.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DAP10 PF07213.11 KER22940.1 - 0.13 12.2 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein DAG1 PF05454.11 KER22940.1 - 0.16 11.3 0.6 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4690 PF15756.5 KER22940.1 - 0.17 12.5 0.5 0.41 11.3 0.5 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage TMEM156 PF15106.6 KER22940.1 - 0.19 11.1 0.7 0.31 10.4 0.7 1.3 1 0 0 1 1 1 0 TMEM156 protein family Protocadherin PF08374.11 KER22940.1 - 0.69 9.9 4.4 0.97 9.4 2.6 1.9 1 1 1 2 2 2 0 Protocadherin RCR PF12273.8 KER22940.1 - 2.8 8.6 5.1 0.94 10.1 0.7 2.5 3 1 0 3 3 2 0 Chitin synthesis regulation, resistance to Congo red Equine_IAV_S2 PF06502.11 KER22940.1 - 6.9 6.8 5.7 2 8.5 1.8 2.2 2 1 0 2 2 1 0 Equine infectious anaemia virus S2 protein Sugar_tr PF00083.24 KER22942.1 - 2.4e-17 62.9 24.8 2.4e-17 62.9 24.8 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KER22942.1 - 3.7e-14 52.4 28.1 3.7e-14 52.4 28.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEMspv1-c74-12 PF11044.8 KER22942.1 - 0.19 11.7 1.1 0.54 10.3 1.1 1.7 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_transf_7C PF02709.14 KER22943.1 - 7.6e-24 83.2 0.0 2.4e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 KER22943.1 - 4.2e-16 58.8 0.0 7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Guanylate_kin PF00625.21 KER22944.1 - 3.8e-30 104.9 0.0 3.2e-27 95.4 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase PDZ PF00595.24 KER22944.1 - 3.8e-12 46.4 1.7 8.7e-12 45.2 1.7 1.6 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 KER22944.1 - 2.6e-06 27.0 0.0 7.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KER22944.1 - 3.8e-05 23.4 0.1 0.00011 22.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain MMR_HSR1 PF01926.23 KER22944.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PDZ_2 PF13180.6 KER22944.1 - 0.0015 18.9 0.2 0.003 17.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain AAA_22 PF13401.6 KER22944.1 - 0.0016 18.7 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SH3_1 PF00018.28 KER22944.1 - 0.0027 17.3 0.3 0.0099 15.5 0.0 2.0 2 0 0 2 2 2 1 SH3 domain AAA_5 PF07728.14 KER22944.1 - 0.0029 17.6 0.0 0.0094 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KER22944.1 - 0.0077 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER22944.1 - 0.0086 16.5 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KER22944.1 - 0.0091 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KER22944.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KER22944.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KER22944.1 - 0.035 14.6 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KER22944.1 - 0.037 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KER22944.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KER22944.1 - 0.05 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KER22944.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KER22944.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tricorn_PDZ PF14685.6 KER22944.1 - 0.096 12.7 0.1 0.44 10.5 0.1 2.1 1 1 0 1 1 1 0 Tricorn protease PDZ domain NTPase_1 PF03266.15 KER22944.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase COX15-CtaA PF02628.15 KER22946.1 - 1.1e-60 205.4 13.9 1.5e-34 119.6 6.1 2.0 2 0 0 2 2 2 2 Cytochrome oxidase assembly protein RPA_C PF08784.11 KER22947.1 - 1.2e-14 54.8 0.4 5.9e-14 52.6 0.0 2.2 2 1 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KER22947.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KER22947.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 LexA_DNA_bind PF01726.16 KER22947.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Peptidase_S9_N PF02897.15 KER22950.1 - 3e-106 355.7 0.0 3.8e-89 299.4 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KER22950.1 - 4.3e-62 209.4 0.0 3.2e-41 141.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KER22950.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLIC PF05783.11 KER22951.1 - 6.8e-141 470.3 2.8 1.3e-78 265.0 2.5 2.9 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 KER22951.1 - 0.00067 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KER22951.1 - 0.0087 16.0 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KER22951.1 - 0.046 13.2 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER22951.1 - 0.051 13.1 0.1 7.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KER22951.1 - 0.066 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RRM_1 PF00076.22 KER22954.1 - 6.5e-17 61.1 0.1 1.1e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER22954.1 - 0.00011 22.3 0.1 0.00028 21.0 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KER22954.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_4 PF13661.6 KER22955.1 - 0.039 14.6 0.0 0.086 13.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KER22956.1 - 3.5e-58 197.2 0.0 1.5e-41 142.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KER22956.1 - 0.1 13.6 0.0 0.28 12.2 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Ldh_1_N PF00056.23 KER22959.1 - 3e-43 147.3 0.9 4.3e-43 146.8 0.9 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KER22959.1 - 1.9e-22 80.0 0.0 3.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 KER22959.1 - 0.00036 20.2 1.6 0.00081 19.0 1.6 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 KER22959.1 - 0.0077 15.8 1.8 0.012 15.1 0.2 1.9 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Poly_export PF02563.16 KER22959.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein AlaDh_PNT_C PF01262.21 KER22959.1 - 0.063 12.6 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 KER22960.1 - 2.3e-43 147.7 0.5 3.2e-43 147.2 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KER22960.1 - 9.8e-06 25.6 0.0 3.5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AlaDh_PNT_C PF01262.21 KER22960.1 - 0.0037 16.6 0.7 0.0055 16.0 0.7 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KER22960.1 - 0.0046 16.6 3.1 0.023 14.3 3.1 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 KER22960.1 - 0.06 12.9 1.6 0.33 10.5 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ldh_1_N PF00056.23 KER22961.1 - 3.2e-41 140.7 0.1 4.4e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KER22961.1 - 1.6e-20 73.7 0.0 2.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 KER22961.1 - 0.0022 17.6 0.9 0.0055 16.3 0.9 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 KER22961.1 - 0.005 16.4 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 KER22961.1 - 0.026 14.6 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain AlaDh_PNT_C PF01262.21 KER22961.1 - 0.032 13.5 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_10 PF05971.12 KER22961.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase N-glycanase_C PF09113.10 KER22962.1 - 0.015 15.1 0.0 0.27 11.0 0.0 2.0 1 1 1 2 2 2 0 Peptide-N-glycosidase F, C terminal GCV_H PF01597.19 KER22964.1 - 9.7e-44 148.2 0.4 1.2e-43 147.9 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KER22964.1 - 0.00052 19.8 0.1 0.00095 18.9 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme ParA PF10609.9 KER22965.1 - 1.5e-79 267.0 0.0 2.5e-79 266.2 0.0 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KER22965.1 - 3e-06 27.3 0.0 0.0015 18.6 0.3 3.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KER22965.1 - 2.2e-05 24.4 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_31 PF13614.6 KER22965.1 - 0.00014 21.8 0.2 0.0023 17.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER22965.1 - 0.00015 22.2 0.0 0.0023 18.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_26 PF13500.6 KER22965.1 - 0.0013 18.6 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 KER22965.1 - 0.0024 17.1 0.1 0.0082 15.4 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase IstB_IS21 PF01695.17 KER22965.1 - 0.029 14.1 0.0 0.078 12.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KER22965.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 KER22965.1 - 0.11 11.7 0.1 8.3 5.6 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ TIP49 PF06068.13 KER22965.1 - 0.27 10.4 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Profilin PF00235.19 KER22967.1 - 1.8e-13 50.9 0.0 2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Profilin Bep_C_terminal PF17841.1 KER22967.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) EAR PF07897.11 KER22968.1 - 0.39 10.4 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Peptidase_C48 PF02902.19 KER22970.1 - 1.9e-19 70.4 0.8 6.6e-06 26.1 0.1 4.1 3 1 0 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain Rieske PF00355.26 KER22972.1 - 1.9e-10 40.6 1.0 2.9e-10 39.9 1.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KER22972.1 - 0.0028 18.1 0.9 0.0047 17.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region SUI1 PF01253.22 KER22975.1 - 5.3e-27 94.2 0.2 1.1e-13 51.5 0.0 2.7 3 0 0 3 3 3 2 Translation initiation factor SUI1 Pre-PUA PF17832.1 KER22975.1 - 8.1e-10 39.3 0.3 2.5e-09 37.7 0.3 1.9 2 0 0 2 2 2 1 Pre-PUA-like domain MIX PF18529.1 KER22975.1 - 0.013 15.2 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial membrane-anchored proteins SWIB PF02201.18 KER22975.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain SRP40_C PF05022.12 KER22981.1 - 1.8e-23 83.2 0.6 3e-23 82.4 0.6 1.4 1 0 0 1 1 1 1 SRP40, C-terminal domain ketoacyl-synt PF00109.26 KER22983.1 - 9.1e-45 153.2 2.9 2.9e-44 151.6 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KER22983.1 - 9.6e-26 90.1 0.5 2e-25 89.1 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KER22983.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RVT_1 PF00078.27 KER22983.1 - 0.0025 17.4 0.0 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KAsynt_C_assoc PF16197.5 KER22983.1 - 0.086 13.3 0.1 0.25 11.8 0.1 1.9 1 1 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension THAP PF05485.12 KER22984.1 - 1.2e-08 35.7 0.0 4.4e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 THAP domain 2-Hacid_dh_C PF02826.19 KER22984.1 - 0.025 13.9 0.0 0.057 12.8 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain S-AdoMet_synt_N PF00438.20 KER22985.1 - 0.059 14.0 0.1 0.14 12.9 0.1 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain Chlorophyllase2 PF12740.7 KER22985.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Pup PF05639.11 KER22985.1 - 8.9 7.3 7.6 20 6.2 0.0 3.6 4 0 0 4 4 4 0 Pup-like protein DUF4509 PF14970.6 KER22986.1 - 4.2e-05 23.5 0.3 4.2e-05 23.5 0.3 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4509) G-patch_2 PF12656.7 KER22987.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 KER22987.1 - 5.7e-05 23.2 0.6 0.0001 22.3 0.0 1.7 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KER22987.1 - 0.0018 18.1 0.2 0.01 15.8 0.4 2.1 2 0 0 2 2 2 1 KOW motif MFS_1 PF07690.16 KER22990.1 - 1.3e-15 57.2 30.4 6.5e-10 38.5 10.4 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily TLE_N PF03920.15 KER22991.1 - 7.9e-49 165.1 5.8 1.3e-48 164.3 5.8 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 KER22991.1 - 2.6e-18 66.0 19.8 0.048 14.5 0.4 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER22991.1 - 1.4e-06 28.5 0.0 0.53 10.6 0.0 3.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TRP_2 PF08344.11 KER22992.1 - 1.9e-26 92.0 0.2 5.1e-26 90.7 0.2 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 KER22992.1 - 2e-26 92.7 17.9 3.5e-26 91.9 17.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 KER22992.1 - 6.5e-11 42.5 1.1 0.0048 17.4 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 KER22992.1 - 1.5e-08 33.8 14.4 5.8e-06 25.3 4.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_2 PF12796.7 KER22992.1 - 2.9e-08 34.2 4.8 0.05 14.2 0.4 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) zf-nanos PF05741.13 KER22992.1 - 0.019 15.2 0.3 0.044 14.0 0.3 1.6 1 0 0 1 1 1 0 Nanos RNA binding domain ApbA_C PF08546.11 KER22992.1 - 0.11 12.7 0.3 28 4.9 0.1 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal DUF5132 PF17195.4 KER22992.1 - 0.46 10.6 6.3 13 5.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) Ank_3 PF13606.6 KER22992.1 - 1.8 9.4 9.6 54 4.9 0.0 6.2 8 0 0 8 8 8 0 Ankyrin repeat CD20 PF04103.15 KER22994.1 - 0.04 14.0 9.1 0.66 10.0 0.5 2.8 1 1 1 2 2 2 0 CD20-like family DUF179 PF02622.15 KER22995.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized ACR, COG1678 MIR PF02815.19 KER22996.1 - 1.5e-47 161.9 2.4 2.8e-47 161.0 0.1 2.7 3 0 0 3 3 3 1 MIR domain RIH_assoc PF08454.11 KER22996.1 - 3.9e-34 116.5 4.5 1.7e-33 114.4 0.1 3.9 3 0 0 3 3 3 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 KER22996.1 - 9.2e-33 113.4 10.0 1.6e-28 99.6 0.2 4.7 5 0 0 5 5 5 3 RIH domain Ins145_P3_rec PF08709.11 KER22996.1 - 4.4e-27 94.7 0.0 1.5e-26 93.0 0.0 1.9 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 KER22996.1 - 3.3e-15 56.0 0.8 9.1e-15 54.5 0.8 1.8 1 0 0 1 1 1 1 Ion transport protein RVT_1 PF00078.27 KER22996.1 - 0.00089 18.8 0.1 0.0032 17.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nup35_RRM PF05172.13 KER22996.1 - 0.088 12.8 0.1 0.49 10.4 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2897 PF11446.8 KER22996.1 - 0.21 11.5 0.6 0.52 10.2 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DEAD PF00270.29 KER22997.1 - 6e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER22997.1 - 3.4e-10 40.2 0.0 8.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KER22997.1 - 1.5e-09 38.5 0.1 4.3e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KER22997.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KELK PF15796.5 KER22997.1 - 0.39 11.2 4.0 0.22 12.0 0.5 2.3 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tropomyosin_1 PF12718.7 KER22997.1 - 0.47 10.6 4.3 0.27 11.4 1.7 1.8 2 0 0 2 2 2 0 Tropomyosin like zf-CpG_bind_C PF12269.8 KER22998.1 - 4.2e-71 239.5 7.9 1.5e-70 237.7 7.9 1.9 1 1 0 1 1 1 1 CpG binding protein zinc finger C terminal domain DUF3565 PF12088.8 KER22998.1 - 9.5 6.3 9.3 1.8 8.6 1.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3565) K_channel_TID PF07941.11 KER23000.1 - 0.0063 17.0 5.0 0.0063 17.0 5.0 2.0 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain SUR7 PF06687.12 KER23000.1 - 0.44 10.1 3.0 12 5.4 4.9 1.9 1 1 1 2 2 2 0 SUR7/PalI family DUF1772 PF08592.11 KER23000.1 - 0.45 10.8 2.9 2.7 8.3 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) EB PF01683.18 KER23001.1 - 1.7e-08 34.6 390.6 0.083 13.2 5.3 27.7 20 4 7 27 27 27 19 EB module NIDO PF06119.14 KER23001.1 - 1.7e-06 28.8 0.0 5.8e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Nidogen-like EGF_3 PF12947.7 KER23001.1 - 0.00086 19.5 8.4 0.00086 19.5 8.4 28.7 27 0 0 27 27 27 18 EGF domain Ig_3 PF13927.6 KER23001.1 - 0.0035 17.9 0.0 0.014 16.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain DUF3591 PF12157.8 KER23002.1 - 0.17 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) zf-met PF12874.7 KER23003.1 - 2.4e-15 56.3 14.2 4.8e-06 26.8 0.5 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER23003.1 - 1.9e-10 40.7 11.9 0.00017 21.8 1.4 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KER23003.1 - 0.00019 21.7 15.2 0.0042 17.4 1.2 3.7 2 1 2 4 4 4 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KER23003.1 - 0.001 19.3 4.4 1.9 8.7 0.0 3.2 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 KER23003.1 - 0.014 15.8 14.0 0.92 10.1 0.3 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Phage_T7_Capsid PF05396.11 KER23003.1 - 0.13 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein zf-DBF PF07535.12 KER23003.1 - 0.22 11.7 4.6 24 5.1 0.1 3.4 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 KER23003.1 - 0.36 11.8 9.1 1.6 9.7 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-U1 PF06220.12 KER23003.1 - 1.8 8.4 10.2 0.67 9.8 0.5 3.6 4 0 0 4 4 4 0 U1 zinc finger DUF3449 PF11931.8 KER23003.1 - 3.5 7.4 9.9 4.7 7.0 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) DDHD PF02862.17 KER23004.1 - 3.7e-24 86.1 0.0 7.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 DDHD domain WWE PF02825.20 KER23004.1 - 0.0061 17.1 0.1 0.024 15.2 0.1 2.0 1 0 0 1 1 1 1 WWE domain ANAPC15 PF15243.6 KER23004.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NAD4L PF06235.11 KER23004.1 - 0.14 12.2 0.6 0.25 11.4 0.6 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) RVT_1 PF00078.27 KER23006.1 - 0.011 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Bcl-2_3 PF15286.6 KER23006.1 - 0.11 13.1 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Histone PF00125.24 KER23008.1 - 0.011 16.1 0.0 0.086 13.2 0.0 1.9 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 C2-set_2 PF08205.12 KER23009.1 - 6.6e-07 29.3 1.4 1.8e-06 28.0 0.0 2.2 2 1 1 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KER23009.1 - 0.002 18.7 2.0 1.3 9.7 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER23009.1 - 0.028 14.6 0.1 0.079 13.1 0.1 1.8 1 0 0 1 1 1 0 Immunoglobulin V-set domain I-set PF07679.16 KER23009.1 - 0.046 13.8 0.4 1.5 8.9 0.1 2.7 3 0 0 3 3 3 0 Immunoglobulin I-set domain ig PF00047.25 KER23009.1 - 0.069 13.3 1.1 2.8 8.2 0.2 2.6 2 0 0 2 2 2 0 Immunoglobulin domain DUF3439 PF11921.8 KER23012.1 - 0.0066 16.4 8.8 0.016 15.1 8.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 KER23012.1 - 4.5 5.1 7.1 5.8 4.8 7.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KER23012.1 - 5.7 6.9 21.6 0.44 10.5 16.6 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 KER23012.1 - 6.6 4.8 13.8 11 4.1 13.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HA2 PF04408.23 KER23014.1 - 8.4e-17 61.4 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KER23014.1 - 6.6e-14 52.2 0.0 1.5e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KER23014.1 - 3e-12 47.1 0.1 0.00014 22.5 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 KER23014.1 - 7.1e-12 45.5 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KER23014.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KER23014.1 - 0.00035 20.9 0.0 0.0007 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER23014.1 - 0.0042 17.4 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER23014.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 KER23014.1 - 0.021 14.6 0.0 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KER23014.1 - 0.09 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KER23014.1 - 0.2 12.1 0.0 0.48 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 KER23015.1 - 6e-74 249.1 35.6 8.8e-73 245.3 35.6 2.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family LapA_dom PF06305.11 KER23015.1 - 0.036 13.9 5.5 0.5 10.2 0.1 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2062 PF09835.9 KER23015.1 - 0.7 9.7 10.1 0.091 12.6 0.6 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF5641 PF18701.1 KER23017.1 - 3.6e-30 104.0 12.3 1.2e-24 86.3 3.4 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5641) DUF4964 PF16334.5 KER23017.1 - 0.058 12.9 1.6 5.1 6.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4964) EptA_B_N PF08019.12 KER23018.1 - 0.0015 18.5 1.9 0.017 15.0 0.6 2.1 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB SLATT_1 PF18181.1 KER23018.1 - 0.093 12.7 0.7 0.23 11.4 0.2 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4212 PF13937.6 KER23018.1 - 0.11 12.9 1.8 2.7 8.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Claudin_2 PF13903.6 KER23018.1 - 0.17 11.7 9.9 0.25 11.1 0.4 2.7 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 KER23018.1 - 0.23 11.1 8.9 0.05 13.2 1.2 2.7 2 1 1 3 3 3 0 SUR7/PalI family MARVEL PF01284.23 KER23018.1 - 0.26 11.3 12.1 18 5.4 12.7 2.7 1 1 2 3 3 3 0 Membrane-associating domain DER1 PF04511.15 KER23019.1 - 2.1e-52 177.8 11.9 9.4e-28 97.4 5.2 2.0 1 1 1 2 2 2 2 Der1-like family ANF_receptor PF01094.28 KER23020.1 - 0.00013 21.2 0.1 0.017 14.3 0.0 2.5 3 0 0 3 3 3 2 Receptor family ligand binding region CPSase_sm_chain PF00988.22 KER23020.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Lig_chan PF00060.26 KER23021.1 - 1.9e-29 102.4 0.4 1.9e-29 102.4 0.4 2.4 3 0 0 3 3 3 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER23021.1 - 1.7e-21 76.6 0.0 2.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KER23021.1 - 3.9e-19 69.0 0.0 3.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 adh_short PF00106.25 KER23023.1 - 1.3e-25 90.0 0.0 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KER23023.1 - 9e-16 58.1 0.0 2.2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER23024.1 - 2.7e-42 144.4 0.0 3.3e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER23024.1 - 2.8e-27 95.8 0.0 3.6e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER23024.1 - 0.011 15.7 0.2 0.043 13.7 0.2 1.8 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KER23024.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KER23024.1 - 0.17 11.9 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_1 PF00036.32 KER23025.1 - 5.6e-07 28.7 0.1 1.2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KER23025.1 - 6.1e-07 28.7 0.1 1.1e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER23025.1 - 5.6e-06 25.9 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KER23025.1 - 0.0018 18.7 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER23025.1 - 0.0095 15.8 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER23026.1 - 5.9e-16 56.8 0.7 8.4e-07 28.1 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23026.1 - 6.1e-13 47.6 1.0 2e-05 24.1 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KER23026.1 - 1.5e-12 46.4 1.0 1.9e-07 30.3 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER23026.1 - 4.2e-11 43.1 1.7 5.3e-11 42.8 1.7 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER23026.1 - 2e-10 40.3 0.6 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER23026.1 - 0.00013 22.3 0.4 0.00015 22.1 0.4 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER23026.1 - 0.005 16.7 0.8 0.026 14.4 0.7 2.2 2 1 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KER23026.1 - 0.082 12.9 0.5 0.12 12.3 0.5 1.4 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand OST-HTH PF12872.7 KER23026.1 - 0.099 12.5 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Shadoo PF14999.6 KER23030.1 - 0.011 15.9 0.6 0.012 15.8 0.6 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective gag-asp_proteas PF13975.6 KER23031.1 - 0.0051 17.3 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER23031.1 - 0.022 15.4 0.0 0.059 14.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease UCR_TM PF02921.14 KER23032.1 - 0.097 13.2 0.4 28 5.3 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region RVT_1 PF00078.27 KER23033.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tam41_Mmp37 PF09139.11 KER23034.1 - 1.7e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Dynein_light PF01221.18 KER23035.1 - 1.2e-17 64.0 1.8 1.8e-17 63.4 1.8 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23035.1 - 1.6e-09 38.0 11.1 5.8e-08 33.1 4.3 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KER23035.1 - 1.2e-08 34.2 5.7 0.005 16.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER23035.1 - 8.7e-08 31.2 9.0 0.00023 20.5 1.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KER23035.1 - 8.2e-07 28.3 8.5 0.0016 17.9 0.2 2.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 KER23035.1 - 1.1e-05 25.7 1.4 1.1e-05 25.7 1.4 1.7 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KER23035.1 - 3.2e-05 23.7 4.7 0.0013 18.5 0.5 2.6 1 1 1 2 2 2 2 EF-hand domain pair PhetRS_B1 PF18262.1 KER23035.1 - 0.01 16.0 0.9 0.061 13.5 0.1 2.4 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Fzo_mitofusin PF04799.13 KER23035.1 - 0.05 13.2 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region Flavodoxin_NdrI PF07972.11 KER23035.1 - 0.05 13.8 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Dynein_light PF01221.18 KER23038.1 - 9.9e-14 51.4 0.1 1.9e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 KER23038.1 - 1e-13 49.7 3.0 1.9e-06 27.0 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER23038.1 - 4.5e-13 48.0 1.3 3e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER23038.1 - 6.6e-13 48.9 0.9 1.8e-12 47.5 0.9 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER23038.1 - 1.6e-10 40.1 3.7 6.6e-06 25.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KER23038.1 - 2.7e-06 27.6 0.2 2.7e-06 27.6 0.2 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KER23038.1 - 3.8e-06 26.6 0.7 1.2e-05 25.0 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KER23038.1 - 0.0008 19.3 1.1 0.0023 17.9 0.2 2.1 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER23038.1 - 0.0053 16.9 1.2 0.075 13.2 1.2 2.4 1 1 0 1 1 1 1 Dockerin type I domain Fer4_12 PF13353.6 KER23038.1 - 0.024 14.9 0.3 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain TerB PF05099.13 KER23038.1 - 0.092 12.7 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB TipAS PF07739.13 KER23038.1 - 0.095 13.3 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain EF-hand_11 PF08976.11 KER23038.1 - 0.11 13.4 0.1 2.1 9.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain HTH_AsnC-type PF13404.6 KER23038.1 - 0.22 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Dynein_light PF01221.18 KER23039.1 - 3.3e-15 56.2 0.0 5.4e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23039.1 - 3.2e-11 43.5 2.2 6.2e-11 42.6 2.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER23039.1 - 1e-10 40.3 4.5 0.00016 21.0 0.3 2.6 2 1 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER23039.1 - 6.2e-10 38.1 2.3 0.00069 19.0 0.3 2.6 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23039.1 - 1.4e-08 34.0 3.5 0.00019 21.1 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KER23039.1 - 5.9e-06 26.6 0.1 1.2e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KER23039.1 - 1.9e-05 24.4 3.3 0.00018 21.3 1.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KER23039.1 - 0.0086 16.4 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Dynein_light PF01221.18 KER23040.1 - 1.7e-27 95.5 6.0 1.8e-13 50.6 0.1 2.9 3 0 0 3 3 3 2 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23040.1 - 8.9e-24 83.7 5.9 2.3e-12 47.2 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER23040.1 - 7.3e-23 78.4 11.9 5.4e-05 22.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER23040.1 - 5e-20 69.7 8.0 3.1e-05 23.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER23040.1 - 5.4e-19 66.8 7.0 0.00021 20.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KER23040.1 - 3.1e-11 43.0 11.8 0.00069 19.4 0.0 4.1 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER23040.1 - 7.4e-11 42.4 5.3 6.2e-06 26.5 0.1 2.8 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER23040.1 - 0.0039 17.1 4.0 1.1 9.2 0.1 3.0 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF3122 PF11320.8 KER23040.1 - 0.053 13.6 0.3 25 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3122) Dynein_light PF01221.18 KER23041.1 - 7.5e-16 58.2 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23041.1 - 2.8e-10 40.5 1.9 3.1e-10 40.4 0.7 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER23041.1 - 6.5e-10 37.8 0.2 2.5e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23041.1 - 3.1e-08 32.9 1.0 0.0012 18.6 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KER23041.1 - 1e-06 27.9 0.0 0.00045 19.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER23041.1 - 1.1e-06 28.3 0.2 3.4e-06 26.8 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER23041.1 - 1.9e-06 28.1 0.4 5.2e-06 26.7 0.2 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region E2F_TDP PF02319.20 KER23041.1 - 0.028 14.4 0.0 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Dockerin_1 PF00404.18 KER23041.1 - 0.34 11.2 2.0 1.6 9.0 2.0 2.0 1 1 0 1 1 1 0 Dockerin type I domain Dynein_light PF01221.18 KER23042.1 - 5.4e-17 61.9 0.2 1.5e-16 60.5 0.1 1.7 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23042.1 - 3.5e-06 27.4 0.9 8.4e-06 26.1 0.9 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF1160 PF06648.11 KER23042.1 - 0.093 12.7 0.1 0.13 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) Dynein_light PF01221.18 KER23043.1 - 2.4e-14 53.4 0.6 4.3e-14 52.6 0.6 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 Glyco_hydro_97 PF10566.9 KER23043.1 - 0.03 13.6 0.3 0.56 9.4 0.1 2.0 2 0 0 2 2 2 0 Glycoside hydrolase 97 PhetRS_B1 PF18262.1 KER23043.1 - 0.074 13.3 0.4 0.75 10.1 0.1 2.4 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TDH PF03347.13 KER23043.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin UQ_con PF00179.26 KER23044.1 - 6.1e-51 171.8 0.0 7e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KER23044.1 - 0.098 12.9 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 KER23044.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Ras PF00071.22 KER23046.1 - 1.8e-44 151.2 0.0 5.1e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER23046.1 - 7.7e-22 77.8 0.0 9.9e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER23046.1 - 0.00012 21.6 0.0 0.00054 19.5 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER23046.1 - 0.034 13.5 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KER23047.1 - 1.7e-51 174.0 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER23047.1 - 3.3e-20 72.5 0.0 4.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER23047.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER23047.1 - 0.023 14.0 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1972 PF09314.11 KER23047.1 - 0.062 12.9 0.0 0.28 10.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) SRPRB PF09439.10 KER23047.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ran_BP1 PF00638.18 KER23049.1 - 8.9e-41 139.0 0.1 1.4e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KER23049.1 - 0.0043 17.0 0.0 0.0076 16.2 0.0 1.4 1 1 0 1 1 1 1 WH1 domain Synaptobrevin PF00957.21 KER23050.1 - 4.5e-25 87.2 3.9 6.6e-25 86.7 3.9 1.2 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KER23050.1 - 0.069 13.2 0.5 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF805 PF05656.14 KER23050.1 - 3.7 8.0 7.3 6.9 7.1 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MFS_1 PF07690.16 KER23052.1 - 8.4e-31 107.2 43.0 1.5e-21 76.8 12.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily STIMATE PF12400.8 KER23054.1 - 0.15 12.6 0.2 0.2 12.2 0.2 1.2 1 0 0 1 1 1 0 STIMATE family Exonuc_VII_L PF02601.15 KER23056.1 - 0.18 11.4 23.4 0.27 10.7 6.9 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit EzrA PF06160.12 KER23056.1 - 0.3 9.2 31.1 0.038 12.2 11.0 3.3 2 2 1 4 4 4 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KER23056.1 - 4.8 6.0 37.6 0.24 10.2 10.6 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Ank_2 PF12796.7 KER23057.1 - 6.2e-85 279.9 15.7 3.3e-13 50.0 0.2 9.3 5 3 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER23057.1 - 2.8e-83 272.9 32.1 6.7e-11 42.2 0.0 12.9 7 4 6 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER23057.1 - 5.3e-78 256.5 22.5 3.6e-11 43.4 0.0 13.8 9 2 5 15 15 15 12 Ankyrin repeats (many copies) Ank PF00023.30 KER23057.1 - 8.4e-76 247.4 30.9 4.3e-06 26.9 0.0 16.1 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 KER23057.1 - 2.1e-69 221.2 27.1 6.7e-05 23.0 0.0 17.8 19 0 0 19 19 19 12 Ankyrin repeat PARP PF00644.20 KER23057.1 - 3.2e-23 82.4 1.8 1.9e-21 76.5 0.3 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.30 KER23057.1 - 3.9e-14 52.8 0.3 7.7e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER23057.1 - 6.4e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BRK PF07533.16 KER23057.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 BRK domain DUF1843 PF08898.10 KER23057.1 - 0.11 13.0 0.1 68 4.1 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) IFT43 PF15305.6 KER23058.1 - 4.9e-24 85.1 0.3 7.1e-24 84.5 0.3 1.2 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Spectrin PF00435.21 KER23059.1 - 1.1e-63 212.2 70.1 1.8e-15 57.3 1.9 11.5 10 2 0 10 10 10 10 Spectrin repeat CH PF00307.31 KER23059.1 - 1.1e-44 151.0 0.0 5.4e-24 84.5 0.0 3.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER23059.1 - 1.1e-08 34.8 0.0 4.4e-06 26.4 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain LexA_DNA_bind PF01726.16 KER23059.1 - 0.0044 16.8 0.0 0.023 14.4 0.0 2.3 1 0 0 1 1 1 1 LexA DNA binding domain DUF4817 PF16087.5 KER23060.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Peptidase_S9 PF00326.21 KER23063.1 - 9.1e-08 31.8 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KER23063.1 - 4.6e-06 25.6 0.0 9.2e-06 24.6 0.0 1.5 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_2 PF02230.16 KER23063.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DnaJ PF00226.31 KER23064.1 - 6.2e-09 35.8 0.2 1.5e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 KER23065.1 - 1.7e-05 24.5 0.0 7.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 GYF domain 2 G-alpha PF00503.20 KER23067.1 - 1.4e-116 389.6 1.5 1.7e-116 389.2 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER23067.1 - 2.8e-13 49.7 0.8 2.7e-09 36.7 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER23067.1 - 0.0041 16.5 0.2 0.65 9.3 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 KER23067.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KER23067.1 - 0.09 13.0 0.1 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rota_NSP4 PF01452.16 KER23067.1 - 0.16 11.6 1.0 0.28 10.8 0.4 1.7 2 0 0 2 2 2 0 Rotavirus non structural protein Complex1_51K PF01512.17 KER23068.1 - 5.2e-50 169.3 0.0 8.2e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KER23068.1 - 1.8e-29 101.6 1.8 4e-29 100.5 0.6 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KER23068.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.11 KER23068.1 - 0.11 13.3 0.7 0.24 12.2 0.7 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Asp PF00026.23 KER23073.1 - 5.3e-33 114.8 0.0 6.2e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER23073.1 - 0.00098 18.9 0.0 0.092 12.5 0.0 2.2 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KER23073.1 - 0.018 15.6 0.2 0.18 12.4 0.1 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER23073.1 - 0.04 14.6 0.2 8.5 7.1 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KER23074.1 - 1.7e-62 211.7 0.0 4e-35 121.8 0.0 3.9 2 2 1 3 3 3 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER23074.1 - 4e-10 39.7 0.0 5.2e-05 23.1 0.0 3.9 3 1 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KER23074.1 - 8.5e-05 23.1 1.7 4.4 8.0 0.0 4.7 4 1 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 KER23074.1 - 9.9e-05 22.8 0.7 1.2 9.7 0.1 4.2 4 2 0 4 4 4 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KER23074.1 - 0.0027 18.0 0.1 10 6.3 0.0 3.4 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Cupredoxin_1 PF13473.6 KER23074.1 - 0.069 13.3 0.0 3 8.0 0.0 2.7 3 0 0 3 3 3 0 Cupredoxin-like domain RVT_1 PF00078.27 KER23075.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ELO PF01151.18 KER23076.1 - 8.8e-29 100.8 0.9 1.3e-28 100.2 0.9 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Chorion_3 PF05387.11 KER23076.1 - 0.076 12.6 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Chorion family 3 ELO PF01151.18 KER23077.1 - 2.1e-56 191.2 17.9 2.6e-56 191.0 17.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF98 PF01947.16 KER23078.1 - 0.019 14.9 0.5 0.031 14.2 0.5 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase DUF3391 PF11871.8 KER23078.1 - 0.44 11.1 1.9 24 5.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Ank_2 PF12796.7 KER23079.1 - 1.7e-56 188.7 11.9 1.2e-12 48.3 0.7 8.0 6 1 2 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER23079.1 - 1.6e-51 172.0 15.4 2.7e-08 34.2 0.5 9.1 7 2 3 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER23079.1 - 1.9e-41 135.3 14.2 0.0015 18.9 0.0 13.3 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KER23079.1 - 2.4e-38 129.7 20.8 4.4e-06 26.9 0.1 11.6 8 2 3 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KER23079.1 - 3.7e-36 122.0 20.6 0.00038 20.8 0.0 12.8 12 0 0 12 12 12 10 Ankyrin repeat Ion_trans PF00520.31 KER23079.1 - 7e-12 45.1 30.1 1.2e-11 44.4 29.4 1.7 1 1 1 2 2 2 1 Ion transport protein ASH PF15780.5 KER23080.1 - 0.013 15.7 0.2 7 6.9 0.0 3.0 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin GDE_N_bis PF14742.6 KER23080.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Lectin_C PF00059.21 KER23081.1 - 1.9e-07 31.7 0.1 2.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain Peptidase_C48 PF02902.19 KER23082.1 - 1.8e-09 37.8 0.1 6.1e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain mRNA_cap_C PF03919.15 KER23082.1 - 0.46 11.1 1.5 1 10.0 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Kri1_C PF12936.7 KER23084.1 - 3.5e-24 84.8 0.1 3.5e-24 84.8 0.1 3.9 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KER23084.1 - 1.5e-18 67.2 2.2 1.5e-18 67.2 2.2 4.9 3 1 1 4 4 4 1 KRI1-like family Peptidase_M24 PF00557.24 KER23088.1 - 1.8e-53 181.3 0.0 2.7e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KER23088.1 - 3.3e-20 72.1 0.0 6.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SAM_1 PF00536.30 KER23088.1 - 4.5e-07 30.2 0.0 8.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER23088.1 - 0.0023 18.0 0.0 0.0072 16.4 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3599 PF12206.8 KER23088.1 - 0.16 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) CUB PF00431.20 KER23090.1 - 1.2e-15 57.8 0.0 1.6e-15 57.4 0.0 1.2 1 1 0 1 1 1 1 CUB domain tRNA-synt_2 PF00152.20 KER23091.1 - 1.1e-77 261.3 0.0 1.4e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KER23091.1 - 5.7e-10 39.0 0.0 9.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KER23091.1 - 6.4e-10 38.9 0.1 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) ApbA_C PF08546.11 KER23091.1 - 0.03 14.5 0.1 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF3835 PF12927.7 KER23091.1 - 0.076 13.9 0.1 6.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Arrestin_N PF00339.29 KER23093.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DZR PF12773.7 KER23098.1 - 0.011 15.7 1.3 0.032 14.2 1.3 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KER23098.1 - 0.02 14.6 3.8 0.052 13.3 3.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KER23098.1 - 0.022 14.1 1.0 0.064 12.7 1.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KER23098.1 - 0.11 13.3 1.8 0.24 12.2 1.8 1.6 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 KER23098.1 - 0.24 11.4 0.9 0.63 10.1 0.7 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sod_Cu PF00080.20 KER23099.1 - 1.8e-44 151.3 6.0 2.8e-44 150.8 6.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RVT_1 PF00078.27 KER23099.1 - 6e-34 117.5 0.0 7.9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ist1 PF03398.14 KER23102.1 - 8.7e-56 188.4 2.6 1.3e-55 187.8 2.6 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UAA PF08449.11 KER23103.1 - 0.072 12.3 10.7 0.09 12.0 10.7 1.2 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.20 KER23103.1 - 0.11 12.7 11.5 0.15 12.2 11.5 1.2 1 0 0 1 1 1 0 EamA-like transporter family TTL PF03133.15 KER23104.1 - 5.7e-81 271.9 0.0 1.1e-80 271.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER23104.1 - 1e-05 24.9 0.0 0.0061 15.8 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER23104.1 - 0.0067 15.7 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TTL PF03133.15 KER23109.1 - 1.7e-56 191.5 0.0 7.3e-56 189.5 0.0 2.0 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family IQCJ-SCHIP1 PF15157.6 KER23109.1 - 0.026 14.4 0.6 0.094 12.6 0.6 1.9 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DAG1 PF05454.11 KER23111.1 - 0.054 12.9 2.8 0.12 11.8 2.8 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.10 KER23111.1 - 0.068 12.6 1.9 0.16 11.4 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_trans_2_3 PF13632.6 KER23111.1 - 0.15 11.9 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF826 PF05696.11 KER23112.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF826) DUP PF00674.18 KER23113.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 1 0 1 1 1 0 DUP family Troponin PF00992.20 KER23115.1 - 1.3e-33 116.2 16.4 1.3e-33 116.2 16.4 2.3 2 0 0 2 2 2 1 Troponin MCD PF05292.11 KER23115.1 - 0.09 12.3 5.4 0.12 11.9 4.5 1.7 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Merozoite_SPAM PF07133.11 KER23115.1 - 0.21 11.5 17.8 0.37 10.8 17.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Neur_chan_memb PF02932.16 KER23115.1 - 2.3 8.2 11.0 0.44 10.6 6.4 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region hDGE_amylase PF14701.6 KER23115.1 - 9.2 5.2 9.5 12 4.9 9.5 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain FAM76 PF16046.5 KER23115.1 - 9.7 5.4 26.9 14 4.9 26.9 1.2 1 0 0 1 1 1 0 FAM76 protein Glycogen_syn PF05693.13 KER23116.1 - 0 1037.8 0.0 0 1037.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 KER23116.1 - 2.7e-06 27.3 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KER23116.1 - 0.0016 18.0 0.0 0.76 9.3 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KER23116.1 - 0.0039 17.6 0.0 1.9 8.9 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KER23116.1 - 0.0068 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ACT_3 PF10000.9 KER23116.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 ACT domain RRM_1 PF00076.22 KER23119.1 - 3.7e-31 106.7 0.4 7.5e-15 54.5 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER23119.1 - 2.2e-07 30.9 0.8 0.00034 20.7 0.1 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KER23119.1 - 0.014 15.4 0.1 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CSD PF00313.22 KER23119.1 - 0.077 12.9 0.3 24 4.9 0.1 3.0 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain rRNA_processing PF08524.11 KER23120.1 - 4.2e-08 33.3 15.0 5.4e-08 33.0 15.0 1.1 1 0 0 1 1 1 1 rRNA processing DEAD PF00270.29 KER23121.1 - 2.5e-17 63.2 0.0 4.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 KER23121.1 - 4.3e-17 61.9 0.0 8.7e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KER23121.1 - 5.2e-16 59.1 1.5 1.6e-15 57.6 1.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 KER23121.1 - 1.2e-15 57.9 0.0 2.1e-14 53.8 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HRDC PF00570.23 KER23121.1 - 1.7e-15 56.7 0.0 4.4e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 KER23121.1 - 0.00033 20.7 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLTH PF10607.9 KER23122.1 - 4.1e-25 88.4 0.2 6.4e-25 87.8 0.2 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SlyX PF04102.12 KER23123.1 - 0.86 10.3 8.7 0.65 10.7 0.2 2.6 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 KER23123.1 - 3.5 6.9 7.8 4.4 6.6 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC2_membrane PF01061.24 KER23124.1 - 2.1e-35 122.1 27.1 2.1e-35 122.1 27.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KER23124.1 - 1.5e-20 74.1 0.1 3.3e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KER23124.1 - 0.00043 20.8 0.0 0.00075 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KER23124.1 - 0.0013 18.4 1.0 0.013 15.2 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KER23124.1 - 0.0016 17.9 0.0 0.012 15.1 0.0 2.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KER23124.1 - 0.0026 17.7 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KER23124.1 - 0.0039 17.0 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KER23124.1 - 0.065 12.3 33.0 0.02 14.0 29.6 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 KER23124.1 - 0.066 12.8 0.0 6.7 6.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KER23124.1 - 0.13 12.7 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Trm112p PF03966.16 KER23125.1 - 3.9e-14 53.0 0.0 5.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.25 KER23126.1 - 1.1e-60 205.3 0.0 1.8e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23126.1 - 2.3e-28 99.2 0.0 3.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER23126.1 - 5.1e-05 22.7 0.3 0.00012 21.6 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER23126.1 - 0.00038 20.1 0.1 0.00081 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KER23126.1 - 0.0057 15.5 0.0 0.0057 15.5 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KER23126.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER23126.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KER23126.1 - 0.088 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase bZIP_C PF12498.8 KER23126.1 - 0.097 13.6 0.1 0.097 13.6 0.1 2.7 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Macoilin PF09726.9 KER23126.1 - 2.1 6.8 9.5 2.8 6.4 9.5 1.1 1 0 0 1 1 1 0 Macoilin family His_Phos_2 PF00328.22 KER23127.1 - 7.4e-23 81.5 0.5 4.4e-20 72.4 0.5 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KER23128.1 - 1.8e-40 139.5 3.7 1.4e-17 64.1 1.2 5.9 3 2 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) DUF1382 PF07131.11 KER23128.1 - 0.0079 16.2 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1382) DUF4378 PF14309.6 KER23128.1 - 0.011 16.1 2.7 0.081 13.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) TES PF08034.11 KER23130.1 - 7.6e-24 83.8 13.4 7.6e-24 83.8 13.4 5.3 3 2 2 5 5 5 2 Trematode eggshell synthesis protein Tyrosinase PF00264.20 KER23131.1 - 2.8e-34 119.3 6.2 4.6e-34 118.6 6.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KER23131.1 - 0.71 10.1 13.2 2.4 8.4 7.1 3.8 3 1 0 3 3 3 0 Laminin EGF domain Pkinase_Tyr PF07714.17 KER23132.1 - 1.8e-54 184.8 0.0 5.1e-52 176.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER23132.1 - 5.9e-25 88.1 0.0 8.8e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Recep_L_domain PF01030.24 KER23132.1 - 7.9e-25 87.2 0.0 5.5e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain fn3 PF00041.21 KER23132.1 - 1.1e-07 32.1 0.7 0.013 15.8 0.1 3.7 3 0 0 3 3 3 2 Fibronectin type III domain Kinase-like PF14531.6 KER23132.1 - 0.0002 20.8 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Keratin_matx PF04579.12 KER23132.1 - 0.047 14.0 3.7 0.058 13.7 1.6 2.2 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein PHO4 PF01384.20 KER23133.1 - 4.6e-62 210.0 0.0 4.6e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 KER23135.1 - 3.3e-82 276.2 0.6 3.8e-82 276.0 0.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Fumarate_red_D PF02313.17 KER23135.1 - 0.088 12.9 2.8 0.65 10.1 0.2 2.9 3 0 0 3 3 3 0 Fumarate reductase subunit D Ig_3 PF13927.6 KER23138.1 - 5.3e-31 107.0 0.5 1.5e-13 51.1 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KER23138.1 - 7.2e-27 93.3 0.0 6.5e-11 42.2 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KER23138.1 - 2.3e-19 69.5 3.8 1.8e-08 34.6 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KER23138.1 - 1.3e-16 60.6 0.0 8.3e-08 32.3 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KER23138.1 - 7.7e-11 42.1 2.0 0.0039 17.3 0.0 4.2 3 1 1 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER23138.1 - 3.1e-05 24.0 0.4 1 9.5 0.0 3.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KER23138.1 - 0.0034 17.4 1.3 1.4 9.1 0.1 3.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain DUF3188 PF11384.8 KER23140.1 - 0.18 11.6 0.0 0.5 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF4381 PF14316.6 KER23143.1 - 0.069 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) OSTbeta PF15048.6 KER23143.1 - 0.1 12.7 0.1 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Relaxase PF03432.14 KER23145.1 - 0.07 12.7 0.0 0.07 12.7 0.0 1.0 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Pkinase PF00069.25 KER23147.1 - 7.4e-60 202.5 0.0 1.1e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23147.1 - 8.6e-30 103.9 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER23147.1 - 0.00042 19.7 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER23147.1 - 0.1 11.6 0.0 0.24 10.3 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain DUF3537 PF12056.8 KER23148.1 - 0.17 10.6 0.2 0.21 10.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) zf-A20 PF01754.16 KER23149.1 - 1.3e-10 41.0 6.6 1.3e-10 41.0 6.6 2.3 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 KER23149.1 - 1e-09 38.4 6.6 1e-09 38.4 6.6 2.3 3 0 0 3 3 3 1 AN1-like Zinc finger CEP19 PF14933.6 KER23149.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 CEP19-like protein UPF0731 PF14982.6 KER23151.1 - 0.074 13.2 1.1 0.11 12.7 0.8 1.4 1 1 0 1 1 1 0 UPF0731 family Toxin_TOLIP PF00087.21 KER23151.1 - 0.44 10.8 11.4 1.2 9.4 11.4 1.9 1 1 0 1 1 1 0 Snake toxin and toxin-like protein UPAR_LY6 PF00021.21 KER23151.1 - 1.8 9.3 12.7 2.5 8.8 10.9 2.2 2 1 0 2 2 2 0 u-PAR/Ly-6 domain TMEM132 PF16070.5 KER23153.1 - 0.047 13.0 0.3 0.23 10.7 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 132 JHY PF15261.6 KER23155.1 - 9.7e-07 29.6 21.2 3.1e-06 27.9 0.1 3.1 3 0 0 3 3 3 2 Jhy protein DUF4615 PF15393.6 KER23155.1 - 4.6 7.8 13.5 0.38 11.3 7.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) BolA PF01722.18 KER23157.1 - 5.2e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein DUF202 PF02656.15 KER23158.1 - 0.081 13.4 6.9 19 5.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ECSCR PF15820.5 KER23158.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.4 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator DUF2070 PF09843.9 KER23158.1 - 1.3 7.2 5.4 1.7 6.8 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SNF PF00209.18 KER23159.1 - 2.5e-20 72.7 9.0 3e-20 72.4 9.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KER23160.1 - 6.7e-17 61.4 54.9 8e-10 38.0 14.1 5.3 4 2 1 5 5 5 5 Sodium:neurotransmitter symporter family Wzy_C_2 PF11846.8 KER23160.1 - 1.5 8.7 4.3 0.54 10.2 0.3 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Annexin PF00191.20 KER23161.1 - 1.2e-80 265.6 10.3 6.4e-24 83.8 0.3 5.1 5 0 0 5 5 5 5 Annexin UBA_2 PF08587.11 KER23161.1 - 0.031 14.4 2.3 1.9 8.7 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF2288 PF10052.9 KER23161.1 - 0.083 13.0 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) Annexin PF00191.20 KER23162.1 - 1.7e-77 255.4 4.9 7.1e-23 80.5 0.1 4.1 4 0 0 4 4 4 4 Annexin NCA2 PF08637.10 KER23162.1 - 0.037 13.2 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 Tubulin-binding PF00418.19 KER23163.1 - 4.9e-13 48.8 0.6 2.3e-12 46.7 0.3 2.0 2 0 0 2 2 2 1 Tau and MAP protein, tubulin-binding repeat Tubulin-binding PF00418.19 KER23164.1 - 4.5e-84 276.1 31.2 4.9e-12 45.6 0.3 8.5 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat EMP70 PF02990.16 KER23168.1 - 1.4e-147 492.6 16.6 2e-147 492.0 16.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Solute_trans_a PF03619.16 KER23169.1 - 2.4e-89 299.4 22.6 2.9e-89 299.1 22.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha bZIP_1 PF00170.21 KER23170.1 - 0.0073 16.4 3.1 0.85 9.8 0.2 3.1 4 0 0 4 4 4 1 bZIP transcription factor ZapB PF06005.12 KER23170.1 - 0.011 16.2 9.0 0.8 10.2 0.6 3.4 2 1 1 3 3 3 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 KER23170.1 - 0.014 15.5 2.8 3.3 7.8 0.1 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 WXG100 PF06013.12 KER23170.1 - 0.014 15.6 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DivIC PF04977.15 KER23170.1 - 0.025 14.3 2.8 1.1 9.0 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator WVELL PF14043.6 KER23170.1 - 0.034 14.0 0.1 0.089 12.6 0.1 1.7 1 0 0 1 1 1 0 WVELL protein DegS PF05384.11 KER23170.1 - 0.052 13.0 4.6 0.2 11.1 0.2 2.5 2 0 0 2 2 2 0 Sensor protein DegS BLOC1_2 PF10046.9 KER23170.1 - 0.053 13.8 1.5 0.64 10.4 0.2 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 KER23170.1 - 0.32 11.1 7.0 6.3 7.0 0.1 3.3 2 1 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 KER23170.1 - 0.62 10.3 2.6 8.8 6.6 0.6 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 KER23170.1 - 0.99 10.1 5.7 7.4 7.3 0.3 2.7 2 1 0 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 KER23170.1 - 1.6 9.5 4.4 4.4 8.0 0.2 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) LRR_6 PF13516.6 KER23171.1 - 1.7e-25 86.8 27.1 6.3e-05 22.7 0.0 10.9 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 KER23171.1 - 1.7e-09 37.8 10.4 0.27 11.7 0.2 6.7 3 2 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER23171.1 - 0.00012 22.2 18.1 39 5.3 0.9 9.3 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 KER23171.1 - 0.0029 17.3 7.3 1.6 8.5 0.0 5.5 4 3 2 7 7 7 2 Leucine rich repeat AMOP PF03782.17 KER23173.1 - 0.026 14.6 2.1 0.041 14.0 2.1 1.3 1 0 0 1 1 1 0 AMOP domain Peptidase_M17 PF00883.21 KER23175.1 - 4.2e-57 193.8 0.0 5.4e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Cdd1 PF11731.8 KER23176.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Pathogenicity locus GST_C_2 PF13410.6 KER23177.1 - 8.5e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KER23177.1 - 0.0085 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER23177.1 - 0.051 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zip PF02535.22 KER23178.1 - 8.3e-81 271.8 12.5 3.7e-78 263.1 12.5 2.3 1 1 0 1 1 1 1 ZIP Zinc transporter GP41 PF00517.17 KER23178.1 - 0.052 13.5 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Retroviral envelope protein YEATS PF03366.16 KER23179.1 - 1.4e-31 108.3 0.6 2.3e-31 107.6 0.6 1.4 1 0 0 1 1 1 1 YEATS family DUF3160 PF11369.8 KER23179.1 - 0.012 14.1 0.1 0.016 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) SBDS_C PF09377.10 KER23179.1 - 0.19 11.8 0.8 0.72 9.9 0.7 1.9 2 1 0 2 2 2 0 SBDS protein C-terminal domain UFC1 PF08694.11 KER23180.1 - 1.5e-83 278.1 0.1 1.6e-83 277.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KER23180.1 - 0.047 14.0 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain Ribosomal_L14 PF00238.19 KER23181.1 - 6.6e-37 126.3 0.1 8.2e-37 126.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_pol_Rpb4 PF03874.16 KER23183.1 - 6.6e-21 74.9 1.6 1.2e-20 74.1 1.6 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 PDT PF00800.18 KER23183.1 - 0.051 13.4 0.1 0.062 13.1 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydratase Ribosomal_L22 PF00237.19 KER23187.1 - 2.4e-11 43.8 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Thg1 PF04446.12 KER23188.1 - 1.7e-47 160.5 0.1 3e-47 159.7 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KER23188.1 - 8.3e-44 148.7 1.3 1.2e-43 148.1 0.6 1.6 2 0 0 2 2 2 1 Thg1 C terminal domain Chordopox_A13L PF05961.11 KER23189.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein rve PF00665.26 KER23191.1 - 1.2e-17 64.2 0.0 2.4e-17 63.2 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KER23191.1 - 0.023 14.8 1.5 0.023 14.8 1.5 2.0 2 0 0 2 2 2 0 Integrase zinc binding domain rve_3 PF13683.6 KER23191.1 - 0.085 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-LYAR PF08790.11 KER23191.1 - 1.9 8.5 4.9 5.1 7.1 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger OGG_N PF07934.12 KER23192.1 - 7.6e-27 93.8 0.0 7.8e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KER23192.1 - 2e-10 41.1 0.0 3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 KER23192.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 KER23192.1 - 0.072 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif WD40 PF00400.32 KER23193.1 - 2e-15 56.9 15.9 0.0023 18.7 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER23193.1 - 0.0018 18.5 0.1 34 4.8 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER23193.1 - 0.049 12.3 0.5 8.2 4.9 0.0 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 SH3_2 PF07653.17 KER23194.1 - 8.5e-20 70.2 0.0 1.1e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KER23194.1 - 1.2e-19 69.8 0.3 3.2e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KER23194.1 - 5.5e-11 41.9 0.0 5.9e-05 22.6 0.0 2.8 2 1 0 2 2 2 2 SH3 domain fn3 PF00041.21 KER23194.1 - 0.0003 21.1 1.5 2.2 8.7 0.0 4.2 3 1 0 3 3 3 2 Fibronectin type III domain zf-C2H2 PF00096.26 KER23194.1 - 0.14 12.7 1.0 0.9 10.1 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L44 PF00935.19 KER23194.1 - 0.29 11.6 0.6 0.58 10.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L44 DUF1702 PF08012.11 KER23195.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) DUF2205 PF10224.9 KER23195.1 - 0.72 9.9 5.4 7.3 6.7 5.4 2.1 1 1 0 1 1 1 0 Short coiled-coil protein HA2 PF04408.23 KER23198.1 - 4.6e-21 75.1 0.3 2.1e-20 73.0 0.0 2.4 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KER23198.1 - 1.5e-18 66.9 0.0 3.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KER23198.1 - 2.1e-12 47.3 0.0 6.1e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KER23198.1 - 7e-10 38.4 0.2 0.00086 18.4 0.0 2.5 1 1 1 2 2 2 2 Type II/IV secretion system protein DEAD PF00270.29 KER23198.1 - 9.8e-08 32.0 0.0 0.00018 21.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KER23198.1 - 8.4e-07 29.3 0.0 0.029 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KER23198.1 - 9e-06 25.5 0.0 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KER23198.1 - 3.3e-05 23.3 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 KaiC DUF2075 PF09848.9 KER23198.1 - 0.00012 21.5 0.0 0.045 13.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KER23198.1 - 0.00025 20.6 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 KER23198.1 - 0.00028 20.9 0.6 3.1 7.7 0.0 3.6 3 0 0 3 3 3 2 NACHT domain AAA_19 PF13245.6 KER23198.1 - 0.00095 19.5 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KER23198.1 - 0.0016 18.9 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KER23198.1 - 0.0018 18.3 0.0 3.4 7.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KER23198.1 - 0.0031 17.6 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 KER23198.1 - 0.0037 17.3 0.5 9.3 6.2 0.0 3.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KER23198.1 - 0.0067 16.2 0.0 5.7 6.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KER23198.1 - 0.0093 15.5 0.0 4.8 6.6 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KER23198.1 - 0.0094 16.1 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KER23198.1 - 0.013 15.1 0.0 9.7 5.7 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SecA_DEAD PF07517.14 KER23198.1 - 0.013 14.8 0.0 5.3 6.3 0.0 2.5 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_23 PF13476.6 KER23198.1 - 0.021 15.3 13.8 4.2 7.8 0.0 3.6 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 KER23198.1 - 0.035 13.3 0.6 5.6 6.0 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KER23198.1 - 0.041 14.4 0.0 25 5.4 0.0 3.0 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 KER23198.1 - 0.077 13.0 0.0 30 4.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KER23198.1 - 0.084 11.8 0.0 8 5.3 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 KER23198.1 - 0.14 12.1 0.1 22 4.9 0.0 2.4 1 1 0 2 2 2 0 RsgA GTPase Herpes_UL73 PF03554.13 KER23198.1 - 0.43 10.6 1.9 22 5.2 0.1 2.6 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein AAA_11 PF13086.6 KER23198.1 - 0.72 9.6 13.1 3.9 7.2 0.0 3.7 3 1 1 4 4 3 0 AAA domain Homeodomain PF00046.29 KER23199.1 - 5.3e-19 67.8 5.0 1.3e-18 66.6 5.0 1.7 1 0 0 1 1 1 1 Homeodomain TrmO PF01980.16 KER23200.1 - 0.039 14.2 0.3 11 6.3 0.0 2.3 2 0 0 2 2 2 0 tRNA-methyltransferase O AID PF18767.1 KER23201.1 - 7.6e-09 35.5 0.2 0.41 10.7 0.0 3.3 1 1 1 3 3 3 3 Activation induced deaminase pPIWI_RE_Y PF18156.1 KER23201.1 - 0.00082 19.8 3.9 8.9 6.7 0.1 3.4 1 1 2 3 3 3 3 pPIWI_RE three-gene island domain Y Imm57 PF15596.6 KER23201.1 - 0.0042 17.4 0.1 44 4.4 0.0 3.3 3 0 0 3 3 3 0 Immunity protein 57 SWIRM-assoc_1 PF16495.5 KER23201.1 - 0.016 15.1 0.3 59 3.7 0.0 3.3 3 0 0 3 3 3 0 SWIRM-associated region 1 Lysozyme_like PF13702.6 KER23201.1 - 0.03 14.0 0.1 5.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Lysozyme-like DUF2107 PF09880.9 KER23201.1 - 0.17 12.0 0.2 51 4.1 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) Snurportin1 PF11538.8 KER23202.1 - 0.053 13.7 0.3 17 5.7 0.2 3.2 2 0 0 2 2 2 0 Snurportin1 mTERF PF02536.14 KER23203.1 - 0.0063 15.5 0.3 1.8 7.4 0.0 2.2 2 0 0 2 2 2 2 mTERF TMEM219 PF14940.6 KER23203.1 - 0.029 14.0 0.0 5.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Transmembrane 219 TMEM100 PF16311.5 KER23204.1 - 0.014 15.0 0.5 0.023 14.3 0.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 LapA_dom PF06305.11 KER23204.1 - 0.033 14.0 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 KER23204.1 - 0.47 10.3 1.4 0.79 9.5 1.4 1.3 1 0 0 1 1 1 0 Vpu protein Dynamin_N PF00350.23 KER23205.1 - 3.3e-40 137.9 0.1 8.3e-40 136.6 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KER23205.1 - 5.4e-06 26.5 0.5 2.7e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 KER23205.1 - 3.1e-05 23.4 0.8 0.00015 21.1 0.0 2.5 3 0 0 3 3 3 1 Dynamin central region DUF1593 PF07632.11 KER23205.1 - 0.00063 19.3 0.3 0.0082 15.6 0.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1593) FeoB_N PF02421.18 KER23205.1 - 0.0016 18.0 0.1 0.19 11.2 0.1 2.4 1 1 1 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KER23205.1 - 0.0028 17.8 0.1 0.59 10.4 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KER23205.1 - 0.012 14.9 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Glyco_trans_1_2 PF13524.6 KER23205.1 - 0.13 12.7 1.7 11 6.5 0.1 3.8 4 0 0 4 4 4 0 Glycosyl transferases group 1 Shugoshin_N PF07558.11 KER23205.1 - 0.17 11.7 2.7 0.98 9.3 2.7 2.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region AAA_21 PF13304.6 KER23205.1 - 0.18 11.6 1.6 4.4 7.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KER23205.1 - 0.31 11.4 0.0 0.31 11.4 0.0 3.4 4 1 0 4 4 4 0 AAA ATPase domain PRP38_assoc PF12871.7 KER23206.1 - 1.5 9.5 34.4 1.9 9.1 34.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DNA_ligase_A_M PF01068.21 KER23207.1 - 3.4e-34 118.3 0.0 7.8e-34 117.1 0.0 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KER23207.1 - 1.4e-29 103.6 0.0 2.6e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KER23207.1 - 3.6e-12 46.5 0.0 1.6e-10 41.2 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KER23207.1 - 7.2e-12 45.8 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KER23207.1 - 3.7e-05 24.0 0.0 8.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KER23207.1 - 6.8e-05 22.9 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 DNA ligase IV Ion_trans PF00520.31 KER23208.1 - 3.1e-30 105.2 15.7 4.3e-30 104.7 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 KER23208.1 - 1.4e-15 57.4 0.0 4.1e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.29 KER23208.1 - 1.2e-13 50.9 0.0 3.5e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KER23208.1 - 1.6e-09 37.6 0.5 1.6e-09 37.6 0.5 2.2 2 0 0 2 2 1 1 Ion channel PAS PF00989.25 KER23208.1 - 1.1e-06 28.6 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KER23208.1 - 1.3e-06 28.6 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KER23208.1 - 7.4e-05 23.0 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold Cupin_2 PF07883.11 KER23208.1 - 0.0037 16.9 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KER23208.1 - 0.034 13.9 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EI24 PF07264.11 KER23208.1 - 0.065 13.5 3.3 0.15 12.3 3.3 1.6 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) cwf21 PF08312.12 KER23208.1 - 0.16 12.1 1.8 0.44 10.8 1.8 1.8 1 0 0 1 1 1 0 cwf21 domain DUF5362 PF17319.2 KER23208.1 - 2.7 7.9 9.2 0.44 10.4 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5362) Ig_2 PF13895.6 KER23210.1 - 6.6e-06 26.4 0.0 0.3 11.5 0.0 3.2 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.19 KER23210.1 - 0.00035 20.7 19.2 0.0023 18.1 5.1 3.2 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 KER23210.1 - 0.0035 17.9 1.1 0.039 14.6 0.0 3.3 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KER23210.1 - 0.061 13.5 0.0 1.5 9.0 0.1 3.1 3 1 0 3 3 3 0 Immunoglobulin V-set domain ig PF00047.25 KER23210.1 - 0.065 13.4 2.1 0.46 10.7 0.1 3.4 3 2 0 3 3 3 0 Immunoglobulin domain Sulfotransfer_3 PF13469.6 KER23211.1 - 1.8e-50 172.3 0.8 1.1e-23 84.8 0.0 3.2 2 2 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER23211.1 - 0.00032 20.3 0.9 0.56 9.6 0.1 2.7 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KER23211.1 - 0.055 13.3 0.1 5 6.9 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase domain Forkhead PF00250.18 KER23215.1 - 2.5e-35 120.6 0.2 5e-35 119.6 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain Na_Ca_ex_C PF16494.5 KER23216.1 - 0.075 13.5 0.0 0.092 13.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain CUE PF02845.16 KER23217.1 - 0.017 14.8 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.10 KER23217.1 - 0.018 15.3 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus G2BR PF18442.1 KER23217.1 - 0.25 11.0 1.3 0.47 10.1 1.3 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Ank_2 PF12796.7 KER23219.1 - 2.8e-65 216.9 26.4 4.7e-14 52.7 1.2 7.9 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER23219.1 - 6.5e-55 182.8 23.9 1.5e-08 35.0 0.1 13.0 6 4 7 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER23219.1 - 8.4e-55 182.1 30.4 1.2e-08 35.0 0.3 12.6 4 3 9 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER23219.1 - 3.7e-48 155.9 10.9 0.00053 20.2 0.0 15.2 15 0 0 15 15 15 10 Ankyrin repeat Ank PF00023.30 KER23219.1 - 8.4e-47 155.7 24.1 3.4e-05 24.1 0.1 13.8 14 1 0 14 14 14 9 Ankyrin repeat Ion_trans PF00520.31 KER23219.1 - 4.1e-08 32.8 17.3 7.7e-08 31.9 17.3 1.4 1 0 0 1 1 1 1 Ion transport protein Sacchrp_dh_NADP PF03435.18 KER23219.1 - 0.081 13.2 0.8 8.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 KER23220.1 - 0.14 12.4 0.9 0.27 11.4 0.9 1.5 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 KER23220.1 - 1 9.9 8.3 8.3 7.0 1.3 3.2 2 1 1 3 3 3 0 Protein of unknown function DUF16 Sec20 PF03908.13 KER23223.1 - 1.7e-07 31.1 1.8 2.5e-07 30.5 0.4 1.9 2 0 0 2 2 2 1 Sec20 DUF3450 PF11932.8 KER23223.1 - 0.027 13.8 3.0 0.37 10.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 KER23223.1 - 0.059 13.4 1.1 3.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Laminin Domain II CC2-LZ PF16516.5 KER23223.1 - 0.1 13.0 1.5 0.19 12.1 0.3 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF433 PF04255.14 KER23224.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Cu2_monoox_C PF03712.15 KER23225.1 - 8.4e-25 87.1 0.0 4.7e-24 84.7 0.0 2.2 2 1 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KER23225.1 - 6.3e-11 42.6 0.1 3.6e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 KER23225.1 - 8.2e-10 38.2 1.7 4.5e-07 29.6 0.1 5.2 6 0 0 6 6 6 1 NHL repeat DUF2457 PF10446.9 KER23225.1 - 0.0049 16.1 1.4 0.0077 15.4 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF3486 PF11985.8 KER23225.1 - 0.2 12.1 0.1 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) wnt PF00110.19 KER23226.1 - 4.4e-69 233.4 20.8 1.2e-35 123.6 15.3 3.1 2 1 1 3 3 3 3 wnt family Pkinase PF00069.25 KER23229.1 - 2.7e-72 243.3 0.0 5.4e-72 242.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23229.1 - 4e-40 137.7 0.1 1.1e-38 133.0 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KER23229.1 - 2.2e-11 43.3 0.0 5.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KER23229.1 - 3e-07 30.0 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 KER23229.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.14 KER23229.1 - 0.0025 17.2 0.1 0.0047 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER23229.1 - 0.014 14.3 0.1 0.031 13.2 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KER23229.1 - 0.016 14.8 0.6 0.029 14.0 0.6 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KER23229.1 - 0.072 12.6 0.3 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UBA_3 PF09288.10 KER23229.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain FTA2 PF13095.6 KER23229.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 tRNA-synt_1 PF00133.22 KER23231.1 - 4.4e-129 431.4 0.0 1.3e-93 314.3 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KER23231.1 - 3.9e-21 75.3 0.0 1.9e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KER23231.1 - 4.5e-10 39.7 0.2 9e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KER23231.1 - 0.00042 19.7 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KER23231.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Tubulin PF00091.25 KER23233.1 - 6.9e-60 202.6 0.0 9.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER23233.1 - 4.8e-52 175.4 0.0 7.6e-52 174.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER23233.1 - 0.00098 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Galactosyl_T PF01762.21 KER23235.1 - 1.4e-08 34.8 0.0 8.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER23235.1 - 0.00094 18.7 0.2 0.01 15.3 0.2 2.1 1 1 0 1 1 1 1 Fringe-like AtpR PF12966.7 KER23235.1 - 0.12 12.8 0.3 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Galactosyl_T PF01762.21 KER23236.1 - 5.6e-06 26.3 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER23236.1 - 0.038 13.4 0.1 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Fringe-like Galactosyl_T PF01762.21 KER23237.1 - 1.5e-05 24.9 0.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER23237.1 - 0.0038 16.7 0.3 0.026 13.9 0.3 2.0 1 1 0 1 1 1 1 Fringe-like zinc_ribbon_16 PF17034.5 KER23238.1 - 7.9e-12 45.5 11.1 1.1e-05 25.6 0.3 3.1 2 1 1 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KER23238.1 - 0.004 16.8 7.4 0.004 16.8 7.4 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type tRNA_Me_trans PF03054.16 KER23240.1 - 8e-88 294.6 0.0 2.2e-80 270.1 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase rve PF00665.26 KER23240.1 - 2.9e-11 43.6 0.0 6.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mito_carr PF00153.27 KER23241.1 - 1.1e-44 150.3 1.8 3.9e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF21 PF01595.20 KER23242.1 - 1.5e-33 116.0 2.1 2.6e-33 115.2 2.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KER23242.1 - 2.5e-05 24.6 0.1 0.00012 22.5 0.0 2.2 2 0 0 2 2 2 1 CBS domain Adaptin_N PF01602.20 KER23243.1 - 7.7e-95 318.4 3.0 1.6e-94 317.4 3.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KER23243.1 - 1.7e-54 183.5 0.0 3.1e-54 182.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KER23243.1 - 1.6e-52 176.8 0.1 9.8e-52 174.3 0.0 2.3 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KER23243.1 - 9e-10 38.8 12.5 4.5e-07 30.0 0.1 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RVT_1 PF00078.27 KER23243.1 - 3.6e-08 33.2 0.0 9.3e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_2 PF13646.6 KER23243.1 - 6.4e-08 32.9 0.6 0.007 16.7 0.0 4.4 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.22 KER23243.1 - 7.1e-08 32.1 0.0 0.018 15.3 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KER23243.1 - 0.0025 18.3 0.4 5.1 7.7 0.0 3.2 3 0 0 3 3 3 2 HEAT-like repeat Amidase PF01425.21 KER23244.1 - 1.1e-60 205.8 0.0 1.6e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Amidase MscS_TM PF12794.7 KER23244.1 - 0.0034 16.3 0.6 0.0095 14.8 0.2 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 Amidase PF01425.21 KER23245.1 - 2.1e-102 343.4 0.0 2.4e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Spc7 PF08317.11 KER23245.1 - 0.18 10.7 1.7 0.35 9.7 1.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.11 KER23245.1 - 1.4 9.6 3.9 4.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Cytochrome b562 Amidase PF01425.21 KER23247.1 - 3.1e-82 277.0 0.0 5e-68 230.1 0.0 2.0 1 1 1 2 2 2 2 Amidase Cytochrom_B562 PF07361.11 KER23247.1 - 0.62 10.7 3.8 0.72 10.6 0.1 2.5 3 0 0 3 3 3 0 Cytochrome b562 Patatin PF01734.22 KER23248.1 - 2.4e-13 50.7 0.3 9.1e-13 48.9 0.0 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase DUF983 PF06170.12 KER23248.1 - 0.064 13.7 0.2 2.5 8.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF983) AA_permease_2 PF13520.6 KER23249.1 - 7.5e-47 160.1 35.9 7.5e-47 160.1 35.9 2.5 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KER23249.1 - 3.6e-30 105.0 31.1 3.6e-30 105.0 31.1 2.7 2 1 1 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 KER23249.1 - 1e-21 76.7 10.8 1e-21 76.7 10.8 3.7 5 0 0 5 5 5 1 C-terminus of AA_permease SH2 PF00017.24 KER23250.1 - 1.4e-10 41.1 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 KER23250.1 - 2.6e-05 24.5 0.0 4.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain Exo84_C PF16528.5 KER23251.1 - 1.9e-12 47.4 4.3 2.1e-10 40.8 0.7 4.2 3 1 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KER23251.1 - 1.8e-06 28.0 2.7 2.9e-06 27.3 0.5 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KER23251.1 - 0.00022 21.3 0.1 0.00067 19.8 0.1 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.12 KER23251.1 - 0.016 13.9 0.2 0.068 11.8 0.0 2.1 2 0 0 2 2 2 0 Dor1-like family ASL_C PF08328.11 KER23251.1 - 0.03 14.4 0.6 0.55 10.4 0.2 2.9 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Bcl-2 PF00452.19 KER23252.1 - 1.3e-14 54.6 0.1 1.9e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family c-SKI_SMAD_bind PF08782.10 KER23252.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 1 1 0 1 1 1 1 c-SKI Smad4 binding domain Y_phosphatase PF00102.27 KER23253.1 - 2.4e-61 207.3 0.0 2e-29 102.8 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KER23253.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KER23253.1 - 0.0034 17.2 0.1 0.0072 16.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SPC12 PF06645.13 KER23253.1 - 0.35 11.0 2.2 0.6 10.2 0.1 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SKG6 PF08693.10 KER23253.1 - 2.4 7.6 7.7 5.6 6.5 7.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_TAF50 PF03326.13 KER23254.1 - 0.045 12.4 0.0 0.052 12.2 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) TRAUB PF08164.12 KER23256.1 - 4.9e-11 43.0 0.0 5.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal DUF4218 PF13960.6 KER23259.1 - 0.0039 16.8 0.7 0.0081 15.8 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) Sacchrp_dh_C PF16653.5 KER23261.1 - 2.3e-78 264.0 0.0 7.4e-78 262.3 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 KER23261.1 - 1.2e-27 96.9 0.0 3.1e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 KER23261.1 - 1.1e-13 51.6 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KER23261.1 - 1.4e-07 31.1 0.0 0.00038 19.8 0.0 3.0 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KER23261.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KER23261.1 - 0.03 14.9 0.0 0.16 12.6 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Eapp_C PF10238.9 KER23262.1 - 1.7e-17 63.9 1.1 1.7e-17 63.9 1.1 1.8 2 1 0 2 2 2 1 E2F-associated phosphoprotein Ank_2 PF12796.7 KER23264.1 - 7.8e-16 58.4 0.1 4.7e-15 55.9 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER23264.1 - 2.6e-15 56.3 0.1 6.6e-09 35.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER23264.1 - 3.3e-13 49.9 0.5 2e-06 28.2 0.0 3.8 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER23264.1 - 5.2e-12 44.9 1.1 3.8e-05 23.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KER23264.1 - 7e-11 42.1 0.7 0.00012 22.3 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat DUF1110 PF06533.12 KER23264.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) PHD PF00628.29 KER23267.1 - 8.4e-06 25.6 8.6 2.1e-05 24.3 8.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KER23267.1 - 0.0083 16.4 0.7 0.025 14.8 0.7 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KER23267.1 - 0.63 10.4 7.9 1.8 9.0 7.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 KER23267.1 - 4.3 7.7 6.7 8.6 6.8 6.7 1.5 1 0 0 1 1 1 0 RING-like domain Glyco_transf_8 PF01501.20 KER23268.1 - 1.7e-22 80.2 0.1 1e-12 48.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KER23268.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative VioE PF18234.1 KER23269.1 - 0.0014 18.8 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Violacein biosynthetic enzyme VioE BRCA-2_OB1 PF09103.10 KER23269.1 - 0.13 12.2 0.2 0.63 10.0 0.0 1.9 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Med26 PF08711.11 KER23271.1 - 1.1e-12 47.8 0.0 2.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Herpes_US9 PF06072.11 KER23271.1 - 6.2 6.8 5.8 1.2 9.1 1.8 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 LIN37 PF15306.6 KER23272.1 - 0.095 12.9 0.7 0.11 12.8 0.7 1.1 1 0 0 1 1 1 0 LIN37 Strep_his_triad PF04270.13 KER23272.1 - 0.53 10.3 2.1 3.2 7.8 0.3 2.1 1 1 1 2 2 2 0 Streptococcal histidine triad protein JmjC PF02373.22 KER23273.1 - 6.5e-29 100.7 1.0 3.4e-28 98.4 1.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.28 KER23273.1 - 1.1e-23 82.0 15.7 7.6e-07 28.7 1.5 6.6 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KER23273.1 - 3.5e-15 54.8 18.1 4e-05 23.4 0.7 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KER23273.1 - 5.7e-12 45.4 0.9 0.48 11.4 0.2 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER23273.1 - 1.2e-10 40.9 7.1 0.033 13.9 1.0 5.9 3 2 2 5 5 5 3 TPR repeat TPR_8 PF13181.6 KER23273.1 - 1.4e-09 37.4 11.8 5.7e-05 23.0 0.8 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER23273.1 - 2.3e-09 37.4 15.2 0.006 16.9 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER23273.1 - 2.6e-08 33.7 11.3 0.22 12.0 0.2 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER23273.1 - 2.9e-06 27.7 9.2 0.013 16.0 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER23273.1 - 2e-05 24.3 8.9 0.002 18.0 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER23273.1 - 0.0006 20.4 6.9 0.26 11.9 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER23273.1 - 0.00075 19.3 1.5 2.3 8.2 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER23273.1 - 0.0024 18.4 6.0 5.1 7.9 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KER23273.1 - 0.0033 17.6 10.5 0.017 15.3 0.1 4.0 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KER23273.1 - 0.045 13.9 4.6 0.079 13.1 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KER23273.1 - 0.046 13.8 0.8 0.57 10.3 0.4 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Cys_rich_FGFR PF00839.17 KER23275.1 - 1.5e-115 377.3 83.0 7e-14 51.7 0.2 15.6 15 1 0 15 15 15 15 Cysteine rich repeat HSP90 PF00183.18 KER23276.1 - 1e-229 763.8 25.3 1.3e-229 763.4 25.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KER23276.1 - 7.3e-14 52.2 0.1 1.4e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KER23276.1 - 1.6e-09 37.7 0.1 4.2e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KER23276.1 - 0.056 13.5 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Tumour suppressor protein RNA_polI_A34 PF08208.11 KER23276.1 - 4.9 7.2 20.7 10 6.1 20.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_C1 PF00112.23 KER23278.1 - 1.5e-47 162.5 0.0 5.3e-31 108.4 0.0 2.0 1 1 1 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER23278.1 - 0.00039 19.3 0.1 0.03 13.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family AAA PF00004.29 KER23279.1 - 9.1e-44 149.1 0.1 2.4e-43 147.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER23279.1 - 3.7e-10 39.4 0.1 8.1e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KER23279.1 - 1.1e-09 38.0 0.1 6.6e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KER23279.1 - 1.7e-08 34.8 0.0 4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KER23279.1 - 1.4e-07 31.6 0.1 4.7e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KER23279.1 - 2.3e-05 24.9 0.2 0.0062 16.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.13 KER23279.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KER23279.1 - 0.00014 21.7 0.0 0.00061 19.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KER23279.1 - 0.00021 21.5 0.6 0.049 13.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KER23279.1 - 0.00048 20.2 0.1 0.0057 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KER23279.1 - 0.00069 19.1 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KER23279.1 - 0.00089 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KER23279.1 - 0.00093 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER23279.1 - 0.0011 19.1 0.0 0.003 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KER23279.1 - 0.0011 18.5 0.0 0.006 16.2 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KER23279.1 - 0.0014 19.2 0.1 0.011 16.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KER23279.1 - 0.0018 18.0 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 KER23279.1 - 0.0028 17.6 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 NTPase TIP49 PF06068.13 KER23279.1 - 0.0063 15.8 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KER23279.1 - 0.0087 15.8 0.1 0.76 9.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 KER23279.1 - 0.013 15.5 0.1 0.064 13.3 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KER23279.1 - 0.013 15.5 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain CENP-Q PF13094.6 KER23279.1 - 0.018 15.3 0.0 0.4 10.9 0.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_7 PF12775.7 KER23279.1 - 0.039 13.5 0.1 0.26 10.8 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KER23279.1 - 0.051 13.1 1.9 0.23 11.0 0.1 2.5 2 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KER23279.1 - 0.066 13.1 0.6 0.56 10.1 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KER23279.1 - 0.07 12.5 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 KER23279.1 - 0.077 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 KER23279.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KER23279.1 - 0.092 13.3 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 1 0 ABC transporter K-box PF01486.17 KER23280.1 - 0.0058 16.8 2.2 0.0089 16.2 2.2 1.3 1 0 0 1 1 1 1 K-box region DUF4142 PF13628.6 KER23280.1 - 0.18 12.1 1.3 0.29 11.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Peptidase_C13 PF01650.18 KER23281.1 - 8.7e-54 182.7 0.2 1.2e-53 182.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER23281.1 - 5.8e-05 23.2 0.9 0.00021 21.3 0.9 1.8 1 1 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.18 KER23281.1 - 0.081 12.1 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C25 Peptidase_C13 PF01650.18 KER23282.1 - 5.2e-97 324.4 3.4 6.2e-97 324.1 3.4 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER23282.1 - 0.00025 21.1 0.1 0.00031 20.8 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER23283.1 - 4.5e-79 265.6 7.5 2.4e-75 253.4 6.8 2.8 2 1 0 2 2 2 1 Peptidase C13 family Peptidase_C13 PF01650.18 KER23284.1 - 1.8e-59 201.3 5.0 7.7e-59 199.3 5.0 1.8 1 1 0 1 1 1 1 Peptidase C13 family MqsA_antitoxin PF15731.5 KER23286.1 - 0.12 12.5 3.3 0.12 12.5 3.3 1.0 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA dsrm PF00035.26 KER23288.1 - 1.4e-14 54.5 0.0 0.013 16.2 0.0 6.1 6 0 0 6 6 6 4 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KER23288.1 - 0.00027 21.1 2.4 0.061 13.6 0.1 4.7 4 1 0 4 4 4 1 double strand RNA binding domain from DEAD END PROTEIN 1 Staufen_C PF16482.5 KER23288.1 - 0.012 15.8 0.2 4.6 7.4 0.1 4.1 4 0 0 4 4 4 0 Staufen C-terminal domain PP2C_2 PF13672.6 KER23290.1 - 6.3e-11 42.3 6.4 0.0001 22.0 0.5 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C DUF1896 PF08989.10 KER23290.1 - 0.2 11.8 0.1 30 4.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) Ank_2 PF12796.7 KER23291.1 - 8.3e-52 173.7 17.9 3e-12 47.0 0.6 8.8 5 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER23291.1 - 8.8e-43 144.2 27.7 2.1e-09 37.7 0.2 12.2 7 5 4 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER23291.1 - 6.6e-37 121.3 33.3 0.0022 18.3 0.1 16.3 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 KER23291.1 - 6.1e-30 102.9 24.8 6.5e-08 32.7 0.3 11.9 10 2 3 13 13 13 7 Ankyrin repeats (many copies) Ank PF00023.30 KER23291.1 - 3.2e-26 90.6 37.6 0.0094 16.4 0.0 14.5 16 0 0 16 16 16 8 Ankyrin repeat FYVE PF01363.21 KER23291.1 - 5.3e-17 61.7 6.9 1.5e-16 60.3 6.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KER23291.1 - 0.11 12.8 4.6 0.26 11.5 4.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger BTB PF00651.31 KER23292.1 - 3.1e-06 27.4 0.0 8.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_S49 PF01343.18 KER23293.1 - 0.026 14.5 0.1 14 5.6 0.0 2.6 3 0 0 3 3 3 0 Peptidase family S49 Phe_tRNA-synt_N PF02912.18 KER23293.1 - 0.19 11.7 0.0 32 4.6 0.0 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain ASC PF00858.24 KER23295.1 - 7.9e-05 21.8 0.2 0.014 14.4 0.5 2.2 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel DUF5383 PF17355.2 KER23295.1 - 0.0031 17.9 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5383) Glyco_hydro_31 PF01055.26 KER23298.1 - 6.3e-141 470.5 5.2 8.2e-141 470.2 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KER23298.1 - 7.2e-24 83.9 2.6 1.6e-23 82.7 0.4 2.9 4 0 0 4 4 4 1 Galactose mutarotase-like Ribophorin_I PF04597.14 KER23299.1 - 1.5e-111 373.7 0.5 2.5e-111 373.0 0.5 1.3 1 0 0 1 1 1 1 Ribophorin I ING PF12998.7 KER23299.1 - 0.089 13.4 4.3 0.24 12.0 0.2 2.6 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Acyl-CoA_ox_N PF14749.6 KER23299.1 - 0.094 13.3 2.3 0.21 12.1 2.3 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal MIB_HERC2 PF06701.13 KER23299.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Mib_herc2 DUF4482 PF14818.6 KER23299.1 - 0.23 12.3 2.2 0.25 12.2 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) PilJ PF13675.6 KER23299.1 - 4.9 7.2 6.5 48 4.0 6.5 2.3 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term LSM PF01423.22 KER23300.1 - 1.5e-18 66.3 0.4 1.8e-18 66.0 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KER23300.1 - 0.00013 22.1 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MCM PF00493.23 KER23301.1 - 1.4e-99 331.7 0.0 9e-99 329.1 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KER23301.1 - 3.3e-33 114.2 0.6 6.1e-33 113.3 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER23301.1 - 1.6e-26 92.5 1.4 4.5e-26 91.1 1.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 KER23301.1 - 1.7e-26 92.6 0.0 4.2e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KER23301.1 - 8.8e-15 55.2 1.2 1.5e-14 54.4 0.4 1.8 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KER23301.1 - 1.9e-06 27.4 0.0 7.2e-06 25.5 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KER23301.1 - 7.3e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER23301.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KER23301.1 - 0.015 15.0 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM_bind PF09739.9 KER23301.1 - 0.048 12.1 0.2 0.08 11.4 0.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_lid_7 PF17867.1 KER23301.1 - 0.22 11.7 1.1 0.89 9.8 0.3 2.3 2 0 0 2 2 2 0 Midasin AAA lid domain Homeodomain PF00046.29 KER23303.1 - 5.2e-24 83.9 4.7 7.6e-24 83.3 4.7 1.3 1 0 0 1 1 1 1 Homeodomain QLQ PF08880.11 KER23303.1 - 0.00018 21.2 0.6 0.00032 20.4 0.6 1.4 1 0 0 1 1 1 1 QLQ NPR2 PF06218.11 KER23304.1 - 2.3e-25 89.3 0.7 9e-14 51.1 0.2 4.3 4 1 0 4 4 4 3 Nitrogen permease regulator 2 Afi1 PF07792.12 KER23304.1 - 0.0033 17.9 0.0 0.0064 17.0 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DIRP PF06584.13 KER23306.1 - 1.4e-37 128.0 0.3 4.8e-37 126.4 0.3 2.0 1 0 0 1 1 1 1 DIRP Snf7 PF03357.21 KER23306.1 - 4.3e-22 78.5 14.3 1.1e-21 77.2 14.3 1.7 1 0 0 1 1 1 1 Snf7 gag-asp_proteas PF13975.6 KER23306.1 - 8.8e-07 29.4 0.0 2.8e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER23306.1 - 2.5e-06 28.0 0.0 1.1e-05 26.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 KER23306.1 - 0.0017 18.6 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease LMBR1 PF04791.16 KER23306.1 - 6.8 5.5 6.1 14 4.4 6.1 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein KIAA1430 PF13879.6 KER23308.1 - 0.0077 17.0 2.6 0.0077 17.0 2.6 2.6 2 1 1 3 3 3 1 KIAA1430 homologue DUF4746 PF15928.5 KER23308.1 - 0.39 10.1 3.7 0.81 9.1 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BRO1 PF03097.18 KER23310.1 - 8.3e-73 245.4 0.1 1.6e-72 244.5 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KER23310.1 - 1.2e-50 172.5 17.8 1.5e-45 155.7 14.5 2.7 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.9 KER23310.1 - 0.0056 17.0 7.9 0.38 11.0 2.7 2.8 2 1 0 2 2 2 2 Zinc finger-containing protein CNH PF00780.22 KER23311.1 - 3.9e-07 29.9 1.0 7.5e-07 29.0 1.0 1.5 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 KER23311.1 - 0.00027 21.2 0.5 1.8 8.8 0.1 3.1 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Kelch_1 PF01344.25 KER23312.1 - 3.6e-37 125.7 7.3 1.1e-07 31.3 0.1 7.3 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 KER23312.1 - 1e-23 82.7 4.5 2.5e-05 24.4 0.0 6.6 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KER23312.1 - 9.3e-15 54.4 0.2 0.028 14.4 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KER23312.1 - 1e-10 41.6 1.0 0.00082 19.6 0.0 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KER23312.1 - 7e-10 38.5 0.8 0.065 13.2 0.0 6.5 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KER23312.1 - 9.4e-09 35.1 2.1 0.86 9.7 0.0 5.6 6 0 0 6 6 6 3 Kelch motif BACK PF07707.15 KER23312.1 - 2.7e-06 27.4 0.2 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Latarcin PF10279.9 KER23312.1 - 0.035 14.5 0.2 0.081 13.3 0.2 1.6 1 0 0 1 1 1 0 Latarcin precursor MRP-S31 PF15433.6 KER23315.1 - 0.037 13.7 6.5 0.055 13.1 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Activator_LAG-3 PF11498.8 KER23315.1 - 0.088 11.8 19.8 0.14 11.1 19.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NHR2 PF08788.11 KER23316.1 - 1.9e-06 27.5 2.6 0.53 10.1 0.1 3.0 1 1 2 3 3 3 3 NHR2 domain like PhdYeFM_antitox PF02604.19 KER23316.1 - 3.2e-05 23.7 0.5 4.9 7.0 0.0 3.3 3 0 0 3 3 3 3 Antitoxin Phd_YefM, type II toxin-antitoxin system MG1 PF17790.1 KER23316.1 - 0.0006 20.2 0.2 11 6.5 0.0 3.1 3 0 0 3 3 3 2 Macroglobulin domain MG1 Retrotrans_gag PF03732.17 KER23316.1 - 0.0092 16.2 0.4 4.6 7.6 0.1 2.8 1 1 2 3 3 3 1 Retrotransposon gag protein PG_binding_2 PF08823.11 KER23316.1 - 0.015 15.6 2.1 33 4.9 0.1 3.1 2 1 1 3 3 3 0 Putative peptidoglycan binding domain ABM PF03992.16 KER23316.1 - 0.02 15.0 4.3 7.8 6.7 0.1 3.1 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase Sbi-IV PF11621.8 KER23316.1 - 0.026 14.9 0.5 19 5.7 0.1 3.1 2 1 1 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI MotCF PF09158.10 KER23316.1 - 0.033 14.2 0.4 13 5.9 0.0 2.5 1 1 2 3 3 3 0 Bacteriophage T4 MotA, C-terminal DUF4777 PF16007.5 KER23316.1 - 0.036 14.3 0.4 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Exo5 PF09810.9 KER23316.1 - 0.075 12.5 2.2 3.1 7.2 0.1 2.7 1 1 2 3 3 3 0 Exonuclease V - a 5' deoxyribonuclease TAN PF11640.8 KER23316.1 - 0.081 13.1 2.5 8.6 6.5 0.1 2.8 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair STAR_dimer PF16544.5 KER23317.1 - 2.4e-21 75.0 2.0 5.2e-21 74.0 2.0 1.5 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 KER23317.1 - 0.0021 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 KH domain zf-RING_UBOX PF13445.6 KER23317.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DBC1 PF14443.6 KER23318.1 - 3.5e-45 153.0 0.0 9.2e-45 151.6 0.0 1.8 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 KER23318.1 - 1.9e-09 37.0 0.4 3.9e-09 36.1 0.4 1.5 1 0 0 1 1 1 1 SAP domain S1-like PF14444.6 KER23318.1 - 1.4e-06 28.2 0.2 3.5e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 S1-like Amb_V_allergen PF03913.13 KER23320.1 - 0.11 12.4 3.8 1.3 9.0 1.3 2.4 2 0 0 2 2 2 0 Amb V Allergen Helicase_C_2 PF13307.6 KER23321.1 - 7.5e-54 182.4 0.0 1.5e-53 181.4 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KER23321.1 - 2.3e-35 121.8 1.6 8.5e-25 87.4 1.1 2.6 2 0 0 2 2 2 2 DEAD_2 zf-RING_4 PF14570.6 KER23321.1 - 0.00026 20.7 2.6 0.00068 19.4 2.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KER23321.1 - 0.0016 18.2 10.0 0.0043 16.9 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER23321.1 - 0.0017 18.1 10.3 0.0046 16.8 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER23321.1 - 0.0047 16.9 10.9 0.01 15.7 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER23321.1 - 0.011 15.6 13.0 0.024 14.5 13.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER23321.1 - 0.47 10.8 11.5 1.5 9.2 11.5 2.0 1 0 0 1 1 1 0 Ring finger domain TNFR_c6 PF00020.18 KER23321.1 - 4.8 7.7 8.2 3.1 8.3 1.9 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Prok-RING_4 PF14447.6 KER23321.1 - 9.9 6.1 17.6 1.9 8.4 13.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SRI PF08236.11 KER23323.1 - 1.8e-16 60.1 0.0 3.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 KER23323.1 - 0.0053 16.8 3.5 0.0053 16.8 3.5 2.4 2 0 0 2 2 2 1 WW domain PLAC8 PF04749.17 KER23331.1 - 2.9e-11 44.2 21.1 2.9e-11 44.2 21.1 1.5 2 0 0 2 2 2 1 PLAC8 family DEAD PF00270.29 KER23333.1 - 5.2e-62 208.7 0.0 7.3e-62 208.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER23333.1 - 4.1e-25 88.3 0.0 8.2e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 KER23333.1 - 2.7e-22 79.1 0.2 5.5e-22 78.1 0.1 1.6 2 0 0 2 2 2 1 SPRY domain CMS1 PF14617.6 KER23333.1 - 0.2 11.0 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DSPc PF00782.20 KER23334.1 - 1.7e-06 27.9 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER23334.1 - 0.0013 18.4 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KER23334.1 - 0.0051 16.9 0.0 0.0069 16.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Hjc PF01870.18 KER23336.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) EF-hand_1 PF00036.32 KER23337.1 - 1.2e-31 105.9 11.8 7.7e-08 31.4 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER23337.1 - 4.9e-29 100.6 3.7 5.1e-16 58.9 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER23337.1 - 8.1e-25 85.2 7.8 1.2e-05 24.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER23337.1 - 3.9e-23 79.3 11.8 9e-07 28.3 0.1 5.2 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 KER23337.1 - 5.5e-21 74.2 12.3 2.1e-13 49.9 2.0 3.8 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER23337.1 - 1e-09 38.7 0.4 0.0006 20.1 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER23337.1 - 7.9e-07 29.0 2.2 0.024 14.6 0.1 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER23337.1 - 1.3e-05 25.3 4.6 0.052 13.8 0.2 3.8 2 2 1 3 3 3 2 Dockerin type I domain EF-hand_9 PF14658.6 KER23337.1 - 0.00022 21.5 0.2 0.051 13.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.13 KER23337.1 - 0.0056 16.7 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KER23337.1 - 0.0083 16.1 0.8 0.29 11.0 0.6 3.0 1 1 0 1 1 1 1 Caleosin related protein VCBS PF13517.6 KER23337.1 - 0.012 16.1 4.6 1.3 9.6 1.0 3.8 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4953 PF16313.5 KER23337.1 - 0.021 14.1 0.0 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 Met-zincin YbjN PF10722.9 KER23337.1 - 0.081 13.0 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Glucos_trans_II PF14264.6 KER23339.1 - 0.0021 17.5 0.7 0.0022 17.4 0.7 1.0 1 0 0 1 1 1 1 Glucosyl transferase GtrII DctM PF06808.12 KER23339.1 - 0.0076 15.1 2.5 0.0092 14.8 2.5 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component COX14 PF14880.6 KER23339.1 - 0.0092 15.8 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF3159 PF11361.8 KER23339.1 - 0.017 14.9 2.3 0.021 14.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Presenilin PF01080.17 KER23339.1 - 0.048 12.4 1.6 0.053 12.3 1.6 1.2 1 0 0 1 1 1 0 Presenilin DUF3040 PF11239.8 KER23339.1 - 0.062 13.6 0.2 0.13 12.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) CD34_antigen PF06365.12 KER23339.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Adeno_E3B PF03376.14 KER23339.1 - 2.4 8.4 9.0 0.7 10.2 1.2 2.1 1 1 1 2 2 2 0 Adenovirus E3B protein MIP PF00230.20 KER23341.1 - 0.0095 15.7 1.8 0.17 11.6 0.1 2.6 3 0 0 3 3 3 2 Major intrinsic protein AtpR PF12966.7 KER23341.1 - 0.75 10.3 5.5 5.8 7.4 0.8 3.1 3 0 0 3 3 3 0 N-ATPase, AtpR subunit GAGA_bind PF06217.12 KER23342.1 - 0.034 14.4 0.0 0.036 14.4 0.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Filo_glycop PF01611.16 KER23342.1 - 0.043 12.8 0.1 0.048 12.6 0.1 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein RhoGAP PF00620.27 KER23343.1 - 2.8e-13 50.0 0.0 1.5e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain PDZ PF00595.24 KER23343.1 - 1.2e-07 32.0 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER23343.1 - 2e-07 30.7 0.1 4.7e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER23343.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DEAD PF00270.29 KER23346.1 - 1.9e-32 112.4 0.0 3.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER23346.1 - 1.4e-21 76.9 0.0 1.9e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KER23346.1 - 3.4e-18 65.6 0.1 9.7e-18 64.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KER23346.1 - 0.00039 20.5 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER23346.1 - 0.018 15.3 0.4 0.094 13.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain RVT_1 PF00078.27 KER23347.1 - 8e-07 28.8 0.0 3.5e-05 23.4 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Bap31 PF05529.12 KER23349.1 - 1.5e-34 118.7 6.7 1.5e-34 118.7 6.7 1.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KER23349.1 - 6.8e-13 48.4 8.6 6.8e-13 48.4 8.6 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain VKOR PF07884.14 KER23349.1 - 1.4e-06 28.5 10.4 3.2e-06 27.4 10.4 1.7 1 1 0 1 1 1 1 Vitamin K epoxide reductase family DUF812 PF05667.11 KER23349.1 - 0.0011 18.0 6.3 0.0013 17.7 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1664 PF07889.12 KER23349.1 - 0.0051 16.9 3.7 0.0081 16.2 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FAM76 PF16046.5 KER23349.1 - 0.019 14.3 4.2 0.024 14.0 4.2 1.2 1 0 0 1 1 1 0 FAM76 protein CC2-LZ PF16516.5 KER23349.1 - 0.055 13.8 8.2 1.7 9.0 7.1 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 KER23349.1 - 0.13 11.1 13.0 0.23 10.3 13.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.13 KER23349.1 - 0.19 11.5 13.5 0.33 10.6 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ADIP PF11559.8 KER23349.1 - 0.2 11.7 12.4 0.41 10.7 12.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KER23349.1 - 0.22 11.3 13.2 0.41 10.4 0.7 3.8 2 1 2 4 4 4 0 Septum formation initiator DUF4407 PF14362.6 KER23349.1 - 0.45 9.8 6.2 1.2 8.4 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 KER23349.1 - 0.63 9.4 11.3 0.98 8.8 11.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Exonuc_VII_L PF02601.15 KER23349.1 - 0.79 9.2 6.8 0.94 9.0 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 KER23349.1 - 1.1 9.7 16.3 2.8 8.5 16.3 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region MRP-S31 PF15433.6 KER23349.1 - 1.4 8.5 9.0 1.9 8.1 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4736 PF15883.5 KER23349.1 - 2.6 7.7 9.3 7.1 6.3 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4736) TDA11 PF17084.5 KER23349.1 - 2.9 6.7 12.2 0.83 8.5 0.7 1.9 1 1 1 2 2 2 0 Topoisomerase I damage affected protein 11 YabA PF06156.13 KER23349.1 - 3.5 8.3 9.2 0.86 10.3 4.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 KER23349.1 - 4.9 7.8 15.6 2.7 8.6 10.9 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 CREPT PF16566.5 KER23349.1 - 6.7 6.9 12.5 2.4 8.3 9.7 1.6 2 1 0 2 2 1 0 Cell-cycle alteration and expression-elevated protein in tumour UPF0242 PF06785.11 KER23349.1 - 9.3 6.3 20.6 42 4.2 20.6 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HECT PF00632.25 KER23350.1 - 5.4e-101 338.1 0.0 7.6e-101 337.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KER23350.1 - 5.9e-47 157.4 20.8 9.1e-13 48.0 0.7 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.30 KER23350.1 - 1.2e-15 57.6 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain MbtH PF03621.13 KER23350.1 - 0.18 11.2 5.2 32 4.1 0.6 4.5 4 1 1 5 5 5 0 MbtH-like protein FBPase PF00316.20 KER23351.1 - 3.9e-71 238.4 0.3 5.2e-71 238.0 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KER23351.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family UQ_con PF00179.26 KER23352.1 - 8.1e-10 38.5 0.8 1.9e-09 37.3 0.8 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_5 PF13857.6 KER23353.1 - 0.069 13.5 0.1 1.6 9.2 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF1799 PF08809.11 KER23354.1 - 0.067 13.4 1.0 0.12 12.5 0.5 1.6 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) Pkinase PF00069.25 KER23356.1 - 2.1e-66 224.0 0.0 5.7e-66 222.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23356.1 - 1.3e-30 106.5 0.0 2.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KER23356.1 - 2.7e-27 94.7 0.1 7.1e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KER23356.1 - 0.0068 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER23356.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RVT_1 PF00078.27 KER23356.1 - 0.034 13.6 0.0 0.093 12.2 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PKcGMP_CC PF16808.5 KER23356.1 - 1.2 9.0 5.2 10 6.1 0.0 3.5 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3341 PF11821.8 KER23357.1 - 0.2 11.3 2.8 9.6 5.8 2.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) UNC-93 PF05978.16 KER23358.1 - 3.7e-32 111.2 6.3 5.1e-32 110.8 6.3 1.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KER23358.1 - 2.1e-10 40.0 7.8 2.6e-10 39.8 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.15 KER23358.1 - 0.94 10.0 4.6 2 8.9 2.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Ribosomal_L22 PF00237.19 KER23361.1 - 4.1e-32 110.5 0.4 1.4e-30 105.6 0.4 2.3 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e A2L_zn_ribbon PF08792.10 KER23361.1 - 0.035 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain NYD-SP28 PF14772.6 KER23362.1 - 7.8e-28 96.5 11.1 7.8e-28 96.5 11.1 5.3 5 1 1 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 KER23362.1 - 4.1e-21 74.8 4.3 4.1e-21 74.8 4.3 4.2 3 2 1 4 4 4 1 Sperm tail C-terminal domain Baculo_PEP_C PF04513.12 KER23362.1 - 0.14 12.2 16.5 0.98 9.5 2.6 4.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GerPC PF10737.9 KER23362.1 - 0.27 11.3 22.8 0.023 14.8 3.9 4.2 2 2 1 3 3 3 0 Spore germination protein GerPC ApoO PF09769.9 KER23362.1 - 1.5 8.8 3.2 62 3.6 0.7 3.6 2 1 0 3 3 3 0 Apolipoprotein O TetR_C_24 PF17932.1 KER23362.1 - 2.4 8.5 5.6 2.7 8.3 0.4 3.2 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NEMO PF11577.8 KER23363.1 - 0.00036 20.5 0.1 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO Halo_GVPC PF05465.13 KER23363.1 - 0.011 16.0 0.5 0.015 15.5 0.5 1.2 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF667 PF05018.13 KER23364.1 - 4e-82 274.4 0.2 4.5e-82 274.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) PapA_C PF16911.5 KER23365.1 - 0.03 14.4 0.0 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus PRP3 PF08572.10 KER23366.1 - 8.9e-75 251.3 7.0 1.4e-74 250.7 7.0 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KER23366.1 - 2.8e-41 141.0 0.3 2.8e-41 141.0 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) eIF_4EBP PF05456.11 KER23366.1 - 0.03 14.2 1.0 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PWWP PF00855.17 KER23367.1 - 3.1e-11 43.5 0.3 1e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 PWWP domain zf-CW PF07496.15 KER23367.1 - 8.8e-07 28.9 2.0 8.8e-07 28.9 2.0 2.3 2 0 0 2 2 2 1 CW-type Zinc Finger DUF5100 PF17029.5 KER23367.1 - 0.0076 16.1 0.1 0.26 11.2 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5100) PWWP PF00855.17 KER23368.1 - 2.6e-12 47.0 0.0 8.1e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 PWWP domain zf-CW PF07496.15 KER23368.1 - 3.8e-07 30.0 4.5 9.7e-07 28.7 4.5 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger DUF4852 PF16144.5 KER23368.1 - 0.0029 17.7 0.3 0.0088 16.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4852) AT_hook PF02178.19 KER23368.1 - 0.12 12.4 4.9 0.27 11.2 4.9 1.7 1 0 0 1 1 1 0 AT hook motif TAXi_N PF14543.6 KER23369.1 - 0.042 14.1 2.3 0.095 12.9 2.3 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Cnd1 PF12717.7 KER23370.1 - 4.1e-45 153.7 5.5 6e-44 149.9 0.1 4.5 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KER23370.1 - 7.4e-30 104.0 0.0 7.4e-30 104.0 0.0 3.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KER23370.1 - 1.4e-05 24.9 10.4 0.8 10.1 0.0 7.7 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 KER23370.1 - 6.2e-05 21.8 1.6 0.00048 18.8 0.4 2.9 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 KER23370.1 - 0.00047 20.5 0.6 0.06 13.7 0.0 4.6 3 2 0 3 3 3 1 HEAT repeats MMS22L_C PF14911.6 KER23370.1 - 0.0017 17.5 0.8 0.0074 15.4 0.0 2.5 3 0 0 3 3 3 1 S-phase genomic integrity recombination mediator, C-terminal Cnd3 PF12719.7 KER23370.1 - 0.009 15.2 1.1 0.032 13.4 0.2 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain BRCT_3 PF18428.1 KER23370.1 - 0.013 15.5 0.0 16 5.7 0.0 3.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RTP1_C1 PF10363.9 KER23370.1 - 0.035 14.3 0.0 3.8 7.7 0.0 3.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KER23370.1 - 0.29 11.7 4.6 0.84 10.2 0.1 4.2 4 1 1 5 5 5 0 HEAT-like repeat DUF755 PF05501.11 KER23370.1 - 1.8 8.8 18.2 0.84 9.9 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF755) 7tm_1 PF00001.21 KER23372.1 - 6.1e-11 42.2 16.3 7.3e-11 41.9 15.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER23372.1 - 6.5e-05 22.7 16.4 6.5e-05 22.7 16.4 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx SPC12 PF06645.13 KER23372.1 - 5.7 7.1 12.7 1.4 9.0 0.1 4.0 3 1 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Peptidase_U4 PF03419.13 KER23373.1 - 0.037 13.3 0.5 0.055 12.8 0.5 1.2 1 1 0 1 1 1 0 Sporulation factor SpoIIGA 7tm_1 PF00001.21 KER23373.1 - 0.082 12.2 1.8 0.1 11.9 1.8 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) L27_1 PF09058.10 KER23373.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 L27_1 RbpA PF13397.6 KER23374.1 - 0.11 13.1 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase-binding protein DUF4543 PF15076.6 KER23375.1 - 0.0064 16.6 0.2 0.0085 16.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) VirJ PF06057.11 KER23375.1 - 0.073 12.9 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) RNA_pol_Rpb8 PF03870.15 KER23376.1 - 1.6e-49 167.7 1.6 1.8e-49 167.5 1.6 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KER23376.1 - 0.00027 21.0 0.9 0.091 12.8 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G FAM176 PF14851.6 KER23376.1 - 0.085 12.5 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 FAM176 family HSP70 PF00012.20 KER23377.1 - 6.5e-255 846.9 10.2 7.4e-255 846.8 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER23377.1 - 5.8e-18 64.8 0.5 5.1e-16 58.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KER23377.1 - 0.0016 18.8 0.3 1.4 9.4 0.1 2.8 2 1 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KER23377.1 - 0.025 13.8 0.6 0.13 11.5 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HU-CCDC81_bac_2 PF18175.1 KER23377.1 - 0.16 11.8 0.6 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CENP_C_N PF15622.6 KER23378.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Glyco_hydro_42C PF08533.10 KER23383.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain CENP-B_dimeris PF09026.10 KER23384.1 - 0.087 13.2 7.8 0.12 12.8 7.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KER23384.1 - 0.1 11.9 5.4 0.11 11.9 5.4 1.0 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KER23384.1 - 0.19 11.4 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 KER23384.1 - 0.24 10.2 1.4 0.26 10.1 1.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 KER23384.1 - 0.36 10.5 6.6 0.38 10.5 6.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 KER23384.1 - 0.47 10.8 7.9 0.28 11.6 6.4 1.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 KER23384.1 - 1.8 7.6 9.1 2.3 7.3 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KER23384.1 - 3.8 5.5 5.3 4 5.4 5.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi GST_C_2 PF13410.6 KER23388.1 - 0.0072 16.3 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_7 PF13499.6 KER23389.1 - 9.2e-13 48.4 6.4 9.2e-06 26.0 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KER23389.1 - 2.9e-11 42.4 4.1 4.6e-07 29.3 0.7 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER23389.1 - 1.6e-10 39.7 8.5 1e-06 27.9 1.2 3.8 4 0 0 4 4 4 3 EF hand UPF0154 PF03672.13 KER23389.1 - 2.1e-06 27.7 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 KER23389.1 - 5.8e-05 22.4 2.4 0.00043 19.7 1.3 2.7 2 0 0 2 2 2 1 EF hand FAM76 PF16046.5 KER23389.1 - 0.0003 20.3 1.7 0.00042 19.8 1.7 1.1 1 0 0 1 1 1 1 FAM76 protein EF-hand_8 PF13833.6 KER23389.1 - 0.00075 19.3 2.6 0.13 12.1 0.3 3.7 2 2 1 3 3 3 2 EF-hand domain pair AIF_C PF14721.6 KER23389.1 - 0.026 14.9 0.2 0.042 14.2 0.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EF-hand_9 PF14658.6 KER23389.1 - 0.056 13.8 0.0 1.7 9.1 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Sec62 PF03839.16 KER23389.1 - 0.19 11.2 4.9 0.27 10.7 4.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2098 PF09871.9 KER23389.1 - 0.2 12.0 3.2 0.5 10.7 3.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DUF4820 PF16091.5 KER23389.1 - 0.31 10.4 2.0 0.53 9.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 KER23389.1 - 0.74 9.5 2.4 1.1 9.0 2.4 1.1 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 KER23389.1 - 1.8 8.6 7.4 6.4 6.8 7.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 KER23389.1 - 2 8.2 10.6 3.7 7.4 10.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus NARP1 PF12569.8 KER23389.1 - 6.1 5.6 10.5 8.5 5.1 10.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FXMR_C2 PF16098.5 KER23389.1 - 9.1 6.9 10.6 1.3 9.5 6.0 2.0 2 1 0 2 2 1 0 Fragile X-related mental retardation protein C-terminal region 2 TIP49 PF06068.13 KER23391.1 - 3.9e-162 539.4 1.3 5.1e-162 539.0 1.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KER23391.1 - 2.5e-26 91.6 0.9 2.5e-26 91.6 0.9 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KER23391.1 - 7.7e-11 42.5 0.6 7e-07 29.7 0.1 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KER23391.1 - 2e-06 27.6 0.6 0.0025 17.6 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER23391.1 - 3.2e-06 27.2 0.1 0.0011 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER23391.1 - 1.1e-05 25.7 0.2 0.079 13.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.15 KER23391.1 - 2e-05 24.1 0.1 3.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 KER23391.1 - 2.6e-05 24.6 3.9 0.0015 18.9 3.9 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER23391.1 - 5.2e-05 23.7 0.2 0.00043 20.7 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KER23391.1 - 0.00013 21.4 0.9 0.006 16.0 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KER23391.1 - 0.00049 19.9 0.1 0.78 9.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KER23391.1 - 0.0011 18.5 0.2 0.0028 17.3 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KER23391.1 - 0.0023 18.2 0.1 0.0086 16.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KER23391.1 - 0.0063 16.0 1.8 0.26 10.7 0.4 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 KER23391.1 - 0.0069 16.1 1.4 0.27 10.9 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KER23391.1 - 0.0075 16.1 0.2 0.017 14.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KER23391.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KER23391.1 - 0.013 14.8 0.3 0.031 13.6 0.3 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KER23391.1 - 0.017 15.6 0.1 0.033 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KER23391.1 - 0.029 13.9 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KER23391.1 - 0.031 14.8 0.2 0.17 12.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 KER23391.1 - 0.032 14.0 0.4 0.067 12.9 0.4 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 KER23391.1 - 0.039 14.0 0.1 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KER23391.1 - 0.042 13.8 1.0 0.11 12.5 0.1 2.1 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KER23391.1 - 0.045 13.9 0.3 0.11 12.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KER23391.1 - 0.061 12.5 0.1 0.099 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 KER23391.1 - 0.07 13.2 0.6 4.1 7.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) PHD PF00628.29 KER23394.1 - 0.028 14.3 7.9 0.043 13.7 7.9 1.4 1 1 0 1 1 1 0 PHD-finger NiFe-hyd_HybE PF11939.8 KER23395.1 - 0.03 14.2 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Slu7 PF11708.8 KER23396.1 - 8.6e-101 337.2 2.6 8.6e-101 337.2 2.6 4.0 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KER23396.1 - 0.08 12.7 0.5 0.16 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KER23396.1 - 0.71 10.1 3.3 1.5 9.0 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Pneumo_att_G PF05539.11 KER23396.1 - 9.3 5.7 15.2 13 5.3 15.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G UPF0242 PF06785.11 KER23398.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Yip1 PF04893.17 KER23398.1 - 0.22 11.3 10.2 0.057 13.1 3.3 2.1 1 1 1 2 2 2 0 Yip1 domain DUF4535 PF15054.6 KER23398.1 - 5.4 6.8 7.3 16 5.4 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) BicD PF09730.9 KER23399.1 - 5e-116 388.9 69.9 5e-116 388.9 69.9 2.3 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.12 KER23399.1 - 0.00052 20.1 16.0 0.00052 20.1 16.0 6.6 6 1 1 7 7 7 3 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KER23399.1 - 0.0092 16.2 1.1 0.0092 16.2 1.1 7.0 4 2 2 6 6 6 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KER23399.1 - 0.0094 16.5 2.1 0.0094 16.5 2.1 8.0 4 2 4 8 8 8 1 Apg6 coiled-coil region Gag_p17 PF00540.18 KER23399.1 - 0.013 15.5 0.7 0.059 13.4 0.1 2.5 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) RVT_1 PF00078.27 KER23400.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SURF6 PF04935.12 KER23402.1 - 2e-21 76.7 34.9 2e-21 76.7 34.9 1.8 2 1 0 2 2 2 1 Surfeit locus protein 6 ASH PF15780.5 KER23403.1 - 0.0037 17.5 0.3 26 5.1 0.0 4.1 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KER23403.1 - 0.015 15.2 0.4 9.5 6.1 0.0 2.7 2 0 0 2 2 2 0 MSP (Major sperm protein) domain SurA_N PF09312.11 KER23404.1 - 0.16 12.0 0.0 2.6 8.1 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain AAA_6 PF12774.7 KER23406.1 - 1.7e-160 533.4 0.0 5.1e-160 531.8 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER23406.1 - 2.7e-145 484.4 6.6 2.7e-145 484.4 6.6 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KER23406.1 - 8.7e-106 353.0 0.0 9e-105 349.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER23406.1 - 1.5e-94 315.3 4.1 7.9e-94 312.9 0.6 3.3 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER23406.1 - 6e-80 267.0 0.0 6.9e-78 260.3 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 KER23406.1 - 3.1e-46 156.4 0.0 9.2e-45 151.6 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KER23406.1 - 7.1e-38 130.5 12.9 1.8e-34 119.3 0.1 2.7 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KER23406.1 - 1.1e-29 103.2 0.1 4.1e-28 98.0 0.0 3.6 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain AAA_lid_11 PF18198.1 KER23406.1 - 6.1e-28 97.7 0.4 2.2e-26 92.6 0.1 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KER23406.1 - 7.3e-20 71.1 0.1 3.2e-19 69.0 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KER23406.1 - 1.8e-16 60.4 0.0 0.0024 17.8 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 KER23406.1 - 4.9e-06 27.0 0.0 2.5 8.5 0.1 4.9 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KER23406.1 - 0.0047 17.3 0.0 5.9 7.3 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 KER23406.1 - 0.0067 16.8 1.9 13 6.1 0.0 5.2 5 0 0 5 5 5 0 AAA ATPase domain AAA_18 PF13238.6 KER23406.1 - 0.0078 16.8 0.0 0.065 13.8 0.0 2.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER23406.1 - 0.021 15.1 0.4 74 3.6 0.0 5.2 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 KER23406.1 - 0.14 11.7 0.0 11 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KER23406.1 - 2.1 8.0 4.5 3.2 7.4 0.1 3.3 5 0 0 5 5 5 0 AAA domain Fib_alpha PF08702.10 KER23408.1 - 0.067 13.4 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RVT_1 PF00078.27 KER23409.1 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box PF00505.19 KER23410.1 - 2.1e-32 111.4 13.3 9.6e-19 67.6 3.5 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KER23410.1 - 1.1e-30 106.0 15.4 9.9e-20 70.9 3.4 2.3 2 0 0 2 2 2 2 HMG-box domain LAL_C2 PF18603.1 KER23410.1 - 0.0066 16.6 0.4 0.011 15.8 0.4 1.3 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 Tub_N PF16322.5 KER23410.1 - 0.093 13.1 10.6 0.18 12.2 10.6 1.5 1 0 0 1 1 1 0 Tubby N-terminal CPSF100_C PF13299.6 KER23410.1 - 0.22 11.7 4.3 0.38 10.9 4.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 KER23410.1 - 1.1 7.4 22.1 1.6 6.9 22.1 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 KER23410.1 - 1.9 6.2 6.8 2.5 5.8 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 KER23410.1 - 3.8 6.8 23.4 6.8 6.0 23.4 1.4 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.18 KER23410.1 - 5.4 5.8 11.9 11 4.8 11.9 1.5 1 0 0 1 1 1 0 Hsp90 protein DNA_pol_phi PF04931.13 KER23410.1 - 8.3 4.4 26.6 2 6.4 23.6 1.5 2 0 0 2 2 2 0 DNA polymerase phi PAH PF02671.21 KER23411.1 - 6e-35 119.1 2.6 3.4e-15 55.9 1.5 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KER23411.1 - 2.1e-32 111.1 0.8 4.4e-32 110.0 0.8 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 KER23411.1 - 2.2e-29 103.1 0.0 1.6e-28 100.3 0.0 2.5 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein PRMT5 PF05185.16 KER23413.1 - 5.1e-56 189.2 0.0 1.9e-31 109.2 0.0 2.2 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KER23413.1 - 9.7e-27 93.8 0.1 1.5e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KER23413.1 - 9.2e-23 81.0 0.0 1.5e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Ubiquitin_4 PF18036.1 KER23415.1 - 5.6e-11 42.3 0.3 0.0011 18.9 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-like domain HD PF01966.22 KER23416.1 - 3.4e-09 37.0 0.1 1e-08 35.4 0.1 2.0 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 KER23416.1 - 0.012 15.3 0.3 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase Laminin_I PF06008.14 KER23416.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain I PIGA PF08288.12 KER23418.1 - 1.4e-38 131.3 0.2 4.5e-38 129.7 0.2 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) PIP5K PF01504.18 KER23418.1 - 4.6e-36 124.5 0.1 2.5e-29 102.4 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_transf_4 PF13439.6 KER23418.1 - 1.1e-31 110.1 1.7 1.5e-31 109.7 0.4 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 FYVE PF01363.21 KER23418.1 - 1e-30 105.7 31.6 1.1e-15 57.5 14.0 2.9 2 0 0 2 2 2 2 FYVE zinc finger Glycos_transf_1 PF00534.20 KER23418.1 - 3.5e-22 78.8 0.0 6.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KER23418.1 - 1.4e-20 74.1 0.1 4.1e-20 72.6 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cpn60_TCP1 PF00118.24 KER23418.1 - 3.6e-18 65.5 0.0 6.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_trans_4_4 PF13579.6 KER23418.1 - 1.2e-14 55.1 0.0 4.5e-14 53.2 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DEP PF00610.21 KER23418.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_trans_4_2 PF13477.6 KER23418.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KER23418.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain zf-CRD PF17979.1 KER23418.1 - 0.53 10.4 20.5 1.3 9.1 4.9 3.2 3 0 0 3 3 2 0 Cysteine rich domain with multizinc binding regions Equine_IAV_S2 PF06502.11 KER23418.1 - 1.5 9.0 4.0 32 4.7 0.3 2.6 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein DZR PF12773.7 KER23418.1 - 1.8 8.7 25.2 3.8 7.6 5.3 3.9 2 1 1 3 3 3 0 Double zinc ribbon TPR_8 PF13181.6 KER23419.1 - 1.8e-13 49.6 4.0 0.0077 16.4 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER23419.1 - 2.3e-09 36.7 5.6 0.033 14.0 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER23419.1 - 1.7e-08 34.0 3.5 3 8.2 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER23419.1 - 9.3e-08 32.3 3.5 0.66 10.9 0.1 6.2 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER23419.1 - 8.5e-06 26.3 0.0 1.2 9.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER23419.1 - 1.1e-05 25.9 0.0 0.22 12.1 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER23419.1 - 1.1e-05 25.4 0.1 1.5 9.3 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER23419.1 - 3.6e-05 23.5 1.0 1.5 9.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER23419.1 - 0.0003 21.0 12.0 2.2 8.6 0.2 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER23419.1 - 0.0035 17.0 1.8 0.03 14.0 0.0 3.4 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 KER23419.1 - 0.0036 17.4 0.2 14 5.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Actin_micro PF17003.5 KER23419.1 - 0.062 12.5 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Putative actin-like family Plus-3 PF03126.18 KER23421.1 - 6e-30 104.0 0.0 1.8e-29 102.5 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain YscJ_FliF_C PF08345.11 KER23422.1 - 0.26 11.6 0.0 0.39 11.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal YgaB PF14182.6 KER23424.1 - 0.051 14.0 0.0 0.16 12.4 0.0 1.7 1 1 1 2 2 2 0 YgaB-like protein WD40 PF00400.32 KER23427.1 - 2.1e-33 113.8 7.7 2.3e-06 28.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER23427.1 - 1.3e-08 35.1 0.1 0.19 12.1 0.0 4.9 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 KER23427.1 - 0.0055 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 KER23427.1 - 0.0079 15.8 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 KER23427.1 - 0.0085 15.4 0.0 2.7 7.2 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 KER23427.1 - 0.045 12.4 0.0 0.087 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ham1p_like PF01725.16 KER23428.1 - 4.8e-53 179.9 0.0 5.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DRY_EERY PF09750.9 KER23430.1 - 2.5e-35 121.7 4.4 2.8e-35 121.5 0.1 2.7 2 0 0 2 2 2 1 Alternative splicing regulator CwsA PF10814.8 KER23430.1 - 0.051 13.7 0.4 0.051 13.7 0.4 2.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA LRR_6 PF13516.6 KER23432.1 - 3.4e-19 67.2 10.8 0.0013 18.6 0.1 6.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KER23432.1 - 9.9e-06 25.8 10.4 0.64 10.5 0.1 4.7 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER23432.1 - 4e-05 23.6 5.4 3.6 8.5 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 KER23432.1 - 0.0028 17.4 12.6 0.088 12.6 1.0 4.3 1 1 4 5 5 5 4 Leucine rich repeat Sdh5 PF03937.16 KER23433.1 - 1.1e-21 76.6 0.0 1.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HAT PF02184.16 KER23435.1 - 0.00019 21.4 0.1 0.00043 20.2 0.1 1.6 1 0 0 1 1 1 1 HAT (Half-A-TPR) repeat TPR_17 PF13431.6 KER23435.1 - 0.0013 18.9 4.5 1 9.9 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KER23435.1 - 0.14 11.9 2.2 0.6 9.8 0.0 3.4 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 KER23436.1 - 0.00016 21.9 8.9 0.0017 18.6 3.9 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KER23436.1 - 0.032 14.1 1.9 0.46 10.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER23436.1 - 0.084 13.0 1.7 0.48 10.5 0.3 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 KER23436.1 - 0.098 13.2 0.2 4.6 7.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PRIMA1 PF16101.5 KER23437.1 - 0.04 14.0 0.3 0.076 13.1 0.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 KER23438.1 - 1e-48 166.0 0.0 1.8e-48 165.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23438.1 - 4.1e-22 78.7 0.2 2.4e-21 76.2 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER23438.1 - 0.00072 19.0 0.3 0.0051 16.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KER23438.1 - 0.023 13.6 0.5 0.058 12.3 0.5 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DNA_pol_B_exo1 PF03104.19 KER23438.1 - 0.12 11.5 0.8 0.17 11.0 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Seadorna_VP7 PF07387.11 KER23438.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CC190 PF15768.5 KER23438.1 - 0.21 11.6 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Pkinase PF00069.25 KER23439.1 - 1.2e-44 152.7 0.0 1.6e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23439.1 - 1.1e-23 83.9 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER23439.1 - 0.0036 16.6 0.0 0.0052 16.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like CC190 PF15768.5 KER23439.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Seadorna_VP7 PF07387.11 KER23439.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_S5 PF00333.20 KER23441.1 - 3e-27 94.4 0.7 5.9e-27 93.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KER23441.1 - 5.2e-25 86.7 0.0 8.8e-25 86.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KER23441.1 - 1.9 9.1 9.4 4 8.1 9.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TPH PF13868.6 KER23442.1 - 1.2e-15 56.9 125.1 1.2e-15 56.9 125.1 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain GRIM-19 PF06212.12 KER23443.1 - 2e-48 163.7 0.3 2.3e-48 163.5 0.3 1.0 1 0 0 1 1 1 1 GRIM-19 protein ubiquitin PF00240.23 KER23444.1 - 2.8e-11 43.0 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KER23444.1 - 3.3e-06 26.8 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KER23444.1 - 0.0007 19.6 0.0 0.55 10.3 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain UN_NPL4 PF11543.8 KER23444.1 - 0.0034 17.8 0.0 0.0077 16.7 0.0 1.6 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.10 KER23444.1 - 0.0041 17.8 0.0 0.0068 17.1 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD TUG-UBL1 PF11470.8 KER23444.1 - 0.0066 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 TUG ubiquitin-like domain TBK1_ULD PF18396.1 KER23444.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Tugs PF17840.1 KER23444.1 - 0.15 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain BCL_N PF04714.13 KER23445.1 - 5e-25 87.3 4.6 8.8e-25 86.5 4.6 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region RVT_1 PF00078.27 KER23446.1 - 0.00017 21.2 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_59 PF02057.15 KER23448.1 - 6.5e-84 281.6 4.1 5.9e-50 170.2 1.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 59 Glyco_hydro_59M PF17387.2 KER23448.1 - 1.8e-37 128.0 0.0 3.1e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 central domain NAM-associated PF14303.6 KER23449.1 - 0.07 13.9 0.1 0.092 13.5 0.1 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sds3 PF08598.11 KER23450.1 - 1.1e-12 48.4 0.0 1.8e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Sds3-like RVT_1 PF00078.27 KER23450.1 - 0.044 13.3 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lge1 PF11488.8 KER23450.1 - 0.34 11.1 2.0 0.9 9.8 2.0 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 JAB PF01398.21 KER23451.1 - 5e-17 62.0 0.3 1.2e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KER23451.1 - 1.1e-10 41.8 0.6 2.6e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KER23451.1 - 5.5e-06 26.2 1.2 8.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF3987 PF13148.6 KER23451.1 - 0.02 13.9 6.0 0.031 13.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CAS_C PF12026.8 KER23451.1 - 0.15 12.1 1.7 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain DUF5401 PF17380.2 KER23451.1 - 0.47 8.5 10.4 0.63 8.1 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA_2 PF07724.14 KER23453.1 - 1.2e-43 149.2 0.0 2.2e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KER23453.1 - 8.7e-10 38.7 0.0 3.3e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KER23453.1 - 2e-07 31.0 0.0 6.3e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KER23453.1 - 6.7e-07 29.8 0.1 3.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KER23453.1 - 3e-05 23.8 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KER23453.1 - 7.5e-05 23.2 0.1 0.0015 18.9 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 KER23453.1 - 0.00041 20.5 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 1 1 Torsin AAA_22 PF13401.6 KER23453.1 - 0.00059 20.1 0.2 0.013 15.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KER23453.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.11 KER23453.1 - 0.0034 17.2 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KER23453.1 - 0.01 15.8 0.1 0.035 14.0 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea YchF-GTPase_C PF06071.13 KER23453.1 - 0.012 15.7 0.3 0.033 14.4 0.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF933) AAA_24 PF13479.6 KER23453.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER23453.1 - 0.032 14.7 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KER23453.1 - 0.039 13.9 0.1 0.49 10.3 0.0 2.5 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 KER23453.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KER23453.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KER23453.1 - 0.15 11.3 0.3 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Prp19 PF08606.11 KER23453.1 - 0.15 12.0 1.9 0.79 9.8 0.2 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like RNA_helicase PF00910.22 KER23453.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pox_I5 PF04713.12 KER23454.1 - 1.3 9.1 5.6 2.2 8.4 1.1 2.7 2 0 0 2 2 2 0 Poxvirus protein I5 PRKG1_interact PF15898.5 KER23455.1 - 6.6e-21 75.1 14.7 1.1e-20 74.4 14.7 1.4 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain FH2 PF02181.23 KER23455.1 - 0.017 14.3 4.6 0.022 13.9 4.6 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain HAUS-augmin3 PF14932.6 KER23455.1 - 0.088 12.4 5.3 0.13 11.9 5.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4140 PF13600.6 KER23455.1 - 0.095 13.1 7.5 0.11 12.9 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40_alt PF14077.6 KER23455.1 - 0.12 12.3 3.4 0.17 11.8 0.3 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 KER23455.1 - 0.15 12.1 11.8 0.76 9.8 11.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 KER23455.1 - 0.24 10.3 0.7 0.28 10.1 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 KER23455.1 - 0.37 9.6 8.9 0.5 9.2 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KER23455.1 - 1.3 8.2 4.3 1.8 7.7 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.13 KER23455.1 - 1.8 8.1 8.0 7.3 6.1 8.0 1.8 1 1 0 1 1 1 0 fzo-like conserved region MCU PF04678.13 KER23455.1 - 2.5 8.2 5.5 3.6 7.7 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter CENP-H PF05837.12 KER23455.1 - 2.6 8.5 11.3 4.1 7.8 10.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) OmpH PF03938.14 KER23455.1 - 4.4 7.6 8.0 6.3 7.1 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 KER23455.1 - 8 7.0 13.5 3.7e+02 1.6 12.9 2.2 1 1 0 1 1 1 0 Cell division protein ZapB PRA1 PF03208.19 KER23457.1 - 0.0028 17.3 0.7 0.0045 16.6 0.7 1.3 1 0 0 1 1 1 1 PRA1 family protein Galactosyl_T PF01762.21 KER23458.1 - 2.2e-43 148.4 0.1 3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase RT_RNaseH PF17917.1 KER23459.1 - 2.7e-20 72.6 0.1 6.3e-20 71.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER23459.1 - 8.8e-17 61.0 0.8 2e-16 59.8 0.3 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KER23459.1 - 3.8e-13 49.3 0.0 8.9e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KER23459.1 - 0.00032 20.9 0.2 0.00095 19.4 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain DENN PF02141.21 KER23461.1 - 4.5e-39 134.3 0.7 1.4e-38 132.7 0.7 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain RUN PF02759.19 KER23461.1 - 9e-15 54.8 0.6 2.8e-07 30.5 0.0 4.0 4 0 0 4 4 4 3 RUN domain dDENN PF03455.19 KER23461.1 - 2.4e-11 43.4 0.3 7.2e-11 41.9 0.3 1.9 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 KER23461.1 - 1.5e-09 38.4 0.0 3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 KER23461.1 - 1.2e-06 29.2 0.0 3.7e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Cyclin_N PF00134.23 KER23464.1 - 1.2e-06 28.3 0.7 2e-06 27.5 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAH PF01426.18 KER23466.1 - 8.8e-10 38.5 0.0 7.2e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 BAH domain Rotamase_3 PF13616.6 KER23468.1 - 1.8e-18 67.1 0.0 4.4e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KER23468.1 - 1.1e-14 55.2 0.0 2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KER23468.1 - 0.0062 17.4 0.0 0.0088 16.9 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Beach PF02138.18 KER23469.1 - 1.9e-34 119.3 0.0 1.4e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.32 KER23469.1 - 9.3e-06 26.3 8.1 0.23 12.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat EGF_2 PF07974.13 KER23470.1 - 0.0056 17.0 6.6 0.0056 17.0 6.6 4.6 4 2 0 4 4 4 2 EGF-like domain Arm_3 PF16186.5 KER23470.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Atypical Arm repeat TSP_1 PF00090.19 KER23471.1 - 0.014 15.6 6.8 0.014 15.6 6.8 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain hEGF PF12661.7 KER23471.1 - 3 8.6 18.1 5.1 7.9 1.6 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF RNA_pol_Rpc34 PF05158.12 KER23473.1 - 1.7e-43 149.3 0.1 3.9e-43 148.1 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit FUR PF01475.19 KER23473.1 - 4e-07 30.2 0.3 0.036 14.2 0.0 3.8 3 1 1 4 4 4 2 Ferric uptake regulator family TrmB PF01978.19 KER23473.1 - 0.0016 18.3 0.2 0.033 14.1 0.1 2.8 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 KER23473.1 - 0.0039 17.1 0.2 3.4 7.7 0.0 3.2 3 1 1 4 4 4 2 Transcriptional regulator PadR-like family ATP-cone PF03477.16 KER23473.1 - 0.035 14.7 0.5 0.24 12.0 0.1 2.4 2 0 0 2 2 2 0 ATP cone domain Dala_Dala_lig_N PF01820.21 KER23473.1 - 0.14 12.6 0.0 0.76 10.3 0.0 2.2 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Suv3_N PF18114.1 KER23473.1 - 0.17 12.0 0.2 1.4 9.1 0.1 2.4 1 1 1 2 2 2 0 Suv3 helical N-terminal domain Amino_oxidase PF01593.24 KER23474.1 - 2.6e-46 158.9 0.0 1.2e-45 156.6 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KER23474.1 - 1.2e-15 57.5 0.1 2.7e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KER23474.1 - 8.7e-09 35.0 0.2 1.5e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KER23474.1 - 2e-07 30.5 2.0 2.8e-07 30.0 2.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KER23474.1 - 4.9e-06 26.2 1.0 7.4e-06 25.6 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KER23474.1 - 7.7e-06 25.4 0.8 1.2e-05 24.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KER23474.1 - 9.1e-06 25.5 2.6 1.9e-05 24.4 2.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KER23474.1 - 1.3e-05 24.6 0.3 2.1e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KER23474.1 - 2.1e-05 23.5 0.5 3.2e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KER23474.1 - 0.00055 19.1 0.5 0.00084 18.5 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KER23474.1 - 0.0007 20.1 1.4 0.0015 19.1 1.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KER23474.1 - 0.0019 17.6 0.3 0.0033 16.8 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KER23474.1 - 0.0054 15.9 0.6 0.0054 15.9 0.6 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KER23474.1 - 0.023 13.9 1.3 0.04 13.2 1.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Endonuclea_NS_2 PF13930.6 KER23474.1 - 0.049 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Trp_halogenase PF04820.14 KER23474.1 - 0.076 11.9 0.9 0.11 11.3 0.9 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Shikimate_DH PF01488.20 KER23474.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FIBP PF05427.11 KER23476.1 - 4.1e-100 335.6 0.6 4.6e-100 335.4 0.6 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Otopetrin PF03189.13 KER23477.1 - 6e-83 279.1 4.7 6e-83 279.1 4.7 2.3 2 1 0 2 2 2 1 Otopetrin PDZ PF00595.24 KER23478.1 - 9.1e-16 58.0 0.1 9.5e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER23478.1 - 1.8e-15 56.5 1.9 4.5e-11 42.4 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 KER23478.1 - 6.9e-05 23.1 0.1 0.0058 16.9 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 KER23478.1 - 0.012 15.6 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain CN_hydrolase PF00795.22 KER23480.1 - 2.2e-27 96.0 0.0 2.5e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA PF00004.29 KER23481.1 - 9.1e-41 139.4 0.0 4.6e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Integrase_H2C2 PF17921.1 KER23481.1 - 5.3e-16 58.5 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KER23481.1 - 2.7e-14 53.3 0.0 5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_lid_3 PF17862.1 KER23481.1 - 4.4e-10 39.2 0.2 1.1e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KER23481.1 - 6.5e-08 32.4 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RT_RNaseH_2 PF17919.1 KER23481.1 - 2.8e-07 30.5 0.0 5.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase AAA_2 PF07724.14 KER23481.1 - 2e-05 24.8 0.0 4.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KER23481.1 - 3.4e-05 23.1 0.0 5.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KER23481.1 - 6.9e-05 23.1 0.3 0.024 14.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain rve PF00665.26 KER23481.1 - 0.00015 21.9 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain AAA_16 PF13191.6 KER23481.1 - 0.00034 21.1 0.2 0.011 16.1 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KER23481.1 - 0.00043 20.1 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER23481.1 - 0.0019 18.2 0.3 0.012 15.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KER23481.1 - 0.0034 17.6 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KER23481.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KER23481.1 - 0.02 14.7 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KER23481.1 - 0.02 15.0 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KER23481.1 - 0.023 14.5 0.1 0.082 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KER23481.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KER23481.1 - 0.056 12.8 0.0 0.77 9.0 0.0 2.4 3 0 0 3 3 3 0 KaiC TIP49 PF06068.13 KER23481.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 KER23481.1 - 0.087 12.4 0.9 0.8 9.2 0.4 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KER23481.1 - 0.089 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KER23481.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KER23481.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain gag_pre-integrs PF13976.6 KER23481.1 - 0.17 11.7 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 1 0 GAG-pre-integrase domain Zeta_toxin PF06414.12 KER23481.1 - 0.19 11.0 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin zf-C3H1 PF10650.9 KER23483.1 - 0.0032 17.2 1.5 0.0068 16.1 1.5 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain KilA-N PF04383.13 KER23484.1 - 0.027 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 KilA-N domain DnaJ PF00226.31 KER23485.1 - 1.5e-23 82.7 0.9 3.4e-23 81.6 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 KER23485.1 - 2.2e-07 30.9 14.1 0.00048 20.3 0.1 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KER23485.1 - 0.029 14.6 7.5 0.79 10.0 0.0 3.5 4 0 0 4 4 4 0 Myb-like DNA-binding domain Tom22 PF04281.13 KER23485.1 - 1.7 8.4 17.1 1.8 8.4 3.4 2.8 2 1 1 3 3 3 0 Mitochondrial import receptor subunit Tom22 SUI1 PF01253.22 KER23486.1 - 7.2e-26 90.5 1.4 8.9e-26 90.2 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2076 PF09849.9 KER23487.1 - 3.3e-06 27.3 0.2 3.7e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KER23487.1 - 5.7e-05 23.1 0.8 8.6e-05 22.6 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Pkinase PF00069.25 KER23490.1 - 3.5e-50 170.8 0.0 6.4e-50 170.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KER23490.1 - 1.3e-35 123.4 0.0 2.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KER23490.1 - 1.4e-25 90.1 0.0 2.5e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KER23490.1 - 2.9e-11 43.1 3.6 9.5e-11 41.4 3.6 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KER23490.1 - 7.5e-10 38.6 0.0 1.9e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER23490.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase C1_2 PF03107.16 KER23490.1 - 0.089 13.1 4.5 0.28 11.5 4.5 1.9 1 0 0 1 1 1 0 C1 domain PH PF00169.29 KER23490.1 - 0.12 12.9 0.0 2.5 8.6 0.0 3.0 2 1 0 2 2 2 0 PH domain PHD PF00628.29 KER23490.1 - 0.23 11.4 4.9 0.31 11.0 2.9 2.3 2 0 0 2 2 2 0 PHD-finger DUF4665 PF15679.5 KER23490.1 - 0.33 11.6 3.4 1.2 9.8 3.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) DUF2524 PF10732.9 KER23490.1 - 5.7 7.3 16.5 0.17 12.2 5.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) SMI1_KNR4 PF09346.10 KER23491.1 - 0.0015 19.0 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KER23491.1 - 0.0026 18.1 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall RVT_1 PF00078.27 KER23492.1 - 0.002 17.7 0.1 0.0087 15.6 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) SVIP PF15811.5 KER23493.1 - 1.2e-13 51.2 8.0 2.7e-13 50.1 8.0 1.6 1 0 0 1 1 1 1 Small VCP/p97-interacting protein SET PF00856.28 KER23493.1 - 0.087 13.2 0.0 0.27 11.6 0.0 1.7 2 1 0 2 2 2 0 SET domain zf-CCCH PF00642.24 KER23495.1 - 7.4e-08 32.1 17.1 0.00056 19.8 0.9 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER23495.1 - 7.6e-05 22.6 20.2 8.3e-05 22.5 2.0 3.3 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 KER23495.1 - 0.00024 21.7 6.9 0.34 11.6 0.0 3.6 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KER23495.1 - 0.0011 18.7 17.8 0.0085 15.9 1.5 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KER23495.1 - 0.0071 16.5 4.8 0.65 10.2 3.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KER23495.1 - 0.028 14.9 21.0 0.19 12.3 1.7 4.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger HMW1C_N PF18071.1 KER23495.1 - 0.26 11.1 0.8 0.68 9.7 0.3 1.9 2 0 0 2 2 2 0 HMW1C N-terminal UPF0113_N PF17833.1 KER23497.1 - 1.9e-24 86.0 0.1 3.4e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KER23497.1 - 1.3e-23 83.0 0.0 2.6e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KER23497.1 - 0.0025 17.7 0.0 0.01 15.8 0.0 2.0 3 0 0 3 3 3 1 PUA domain ALMS_motif PF15309.6 KER23498.1 - 0.0005 20.5 0.8 0.0005 20.5 0.8 4.6 5 0 0 5 5 5 2 ALMS motif PaaX_C PF08223.11 KER23498.1 - 0.011 16.0 0.9 0.026 14.8 0.0 2.0 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain 7tm_1 PF00001.21 KER23499.1 - 4.7e-62 209.7 7.3 7e-62 209.1 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER23499.1 - 1.6e-10 41.1 11.3 2.4e-10 40.5 11.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KER23499.1 - 2.1e-09 37.1 12.7 3.6e-09 36.4 12.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 KER23499.1 - 0.0017 18.2 10.7 0.0044 16.8 10.7 1.6 1 1 0 1 1 1 1 Olfactory receptor HLH PF00010.26 KER23500.1 - 6.6e-16 58.0 0.3 6.6e-16 58.0 0.3 2.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Calpain_III PF01067.22 KER23501.1 - 2.1e-18 66.9 0.0 3.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KER23502.1 - 1.4e-94 316.4 0.0 2.4e-57 194.2 0.0 2.1 1 1 1 2 2 2 2 Calpain family cysteine protease Serpin PF00079.20 KER23503.1 - 1.5e-88 297.6 0.0 1.7e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) RE_NgoPII PF09521.10 KER23503.1 - 0.16 11.1 0.0 9.9 5.2 0.0 2.2 2 0 0 2 2 2 0 NgoPII restriction endonuclease Asp PF00026.23 KER23504.1 - 2.4e-16 60.0 0.0 5.3e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER23504.1 - 5.3e-10 39.8 0.1 2.1e-07 31.3 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 KER23505.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Tox-HNH-HHH PF15637.6 KER23505.1 - 0.042 14.0 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif RA PF00788.23 KER23507.1 - 4e-08 33.8 0.0 9.6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.24 KER23507.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RVT_1 PF00078.27 KER23508.1 - 8.2e-06 25.5 0.1 1.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0506 PF11703.8 KER23509.1 - 9.8e-12 45.1 24.2 1.3e-11 44.7 24.2 1.2 1 0 0 1 1 1 1 UPF0506 Conotoxin_I2 PF17557.2 KER23509.1 - 0.0066 16.5 21.3 0.012 15.7 9.1 2.4 2 0 0 2 2 2 2 I2-superfamily conotoxins Dickkopf_N PF04706.12 KER23509.1 - 0.0069 16.8 24.1 0.049 14.1 24.1 2.1 1 1 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region GAS2 PF02187.17 KER23510.1 - 2e-25 88.6 0.1 9.1e-25 86.5 0.0 2.3 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_6 PF13405.6 KER23510.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KER23510.1 - 0.021 14.4 0.0 0.068 12.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KER23510.1 - 0.073 13.5 0.0 0.45 11.0 0.0 2.5 1 0 0 1 1 1 0 EF-hand domain pair CCDC74_C PF14917.6 KER23510.1 - 0.29 11.7 5.4 0.17 12.4 0.9 3.1 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal Alpha-amylase PF00128.24 KER23512.1 - 4.1e-22 79.2 0.6 5.1e-17 62.4 1.1 2.7 2 1 0 2 2 2 2 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 KER23512.1 - 2.2e-15 56.0 0.1 4.2e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus CorC_HlyC PF03471.17 KER23513.1 - 0.025 14.6 0.1 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Transporter associated domain LSM PF01423.22 KER23514.1 - 1.5e-19 69.4 0.1 2.2e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain Glutaredoxin PF00462.24 KER23514.1 - 0.034 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Abhydrolase_1 PF00561.20 KER23516.1 - 1.8e-09 37.7 0.0 5.8e-09 36.0 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER23516.1 - 2.3e-09 36.9 0.0 8.9e-09 35.0 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 RRM_1 PF00076.22 KER23516.1 - 2.4e-08 33.7 0.0 7e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.7 KER23516.1 - 4.1e-08 34.1 1.3 8.4e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KER23516.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exo_endo_phos_2 PF14529.6 KER23516.1 - 0.00083 19.2 0.2 0.0022 17.8 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PWI PF01480.17 KER23516.1 - 0.0015 18.8 0.0 0.0038 17.5 0.0 1.7 1 0 0 1 1 1 1 PWI domain Peptidase_S9 PF00326.21 KER23516.1 - 0.0069 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DSL PF01414.19 KER23517.1 - 3.8e-07 30.3 3.6 3.8e-07 30.3 3.6 3.0 2 1 1 3 3 3 1 Delta serrate ligand EGF PF00008.27 KER23517.1 - 0.011 16.1 3.0 0.011 16.1 3.0 2.2 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 KER23517.1 - 0.015 15.9 2.0 0.015 15.9 2.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF FXa_inhibition PF14670.6 KER23517.1 - 0.27 11.5 6.5 2.7 8.4 2.2 2.7 1 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site DUF2013 PF09431.10 KER23520.1 - 2.1e-12 47.4 0.0 1.1e-09 38.6 0.0 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF2013) SH3_9 PF14604.6 KER23520.1 - 1.3e-08 34.6 0.1 2.6e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER23520.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 KER23520.1 - 0.17 11.6 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain PCSK9_C1 PF18459.1 KER23521.1 - 0.11 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain TMEM51 PF15345.6 KER23526.1 - 4.4 7.1 7.4 1.5 8.6 3.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3185 PF11381.8 KER23526.1 - 7.3 6.7 12.1 31 4.7 7.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DSL PF01414.19 KER23527.1 - 4.9e-12 45.9 0.7 4.9e-12 45.9 0.7 5.3 3 1 2 6 6 6 1 Delta serrate ligand EGF PF00008.27 KER23527.1 - 1.5e-08 34.7 17.6 5.7e-06 26.5 7.4 4.9 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 KER23527.1 - 0.00022 21.5 6.2 0.00022 21.5 6.2 5.7 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.7 KER23527.1 - 0.009 16.6 2.4 0.009 16.6 2.4 6.2 5 0 0 5 5 5 1 Human growth factor-like EGF RGS PF00615.19 KER23528.1 - 1.2e-09 38.5 2.0 2.8e-05 24.4 0.0 3.4 3 1 0 3 3 3 2 Regulator of G protein signaling domain RGS-like PF09128.11 KER23528.1 - 0.049 13.3 0.7 0.51 10.0 0.0 2.6 3 0 0 3 3 3 0 Regulator of G protein signalling-like domain RGS PF00615.19 KER23529.1 - 0.001 19.3 1.9 0.0078 16.5 0.0 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain Ntox17 PF15524.6 KER23529.1 - 0.038 14.3 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 Novel toxin 17 eRF1_1 PF03463.15 KER23530.1 - 4.1e-44 149.7 1.0 8e-44 148.8 1.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KER23530.1 - 1e-29 103.6 0.1 1.7e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KER23530.1 - 7.7e-23 81.1 0.2 2.2e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF3134 PF11332.8 KER23531.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) DUF4516 PF14990.6 KER23531.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF2870 PF11069.8 KER23532.1 - 1e-43 147.6 0.1 1e-43 147.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 KER23532.1 - 0.024 14.4 0.0 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family PDZ PF00595.24 KER23533.1 - 2.6e-05 24.5 0.0 5.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER23533.1 - 0.0027 17.5 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Sulfotransfer_4 PF17784.1 KER23534.1 - 2.9e-107 357.4 7.7 1.8e-43 148.9 0.0 3.1 3 0 0 3 3 3 3 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER23534.1 - 9.2e-06 26.2 1.5 0.0092 16.4 0.1 3.5 3 2 0 3 3 3 2 Sulfotransferase family Lar_restr_allev PF14354.6 KER23534.1 - 0.0079 16.5 2.8 3.1 8.2 0.1 3.4 3 0 0 3 3 3 1 Restriction alleviation protein Lar PKD_channel PF08016.12 KER23534.1 - 0.069 11.8 4.2 0.44 9.2 0.1 2.8 4 0 0 4 4 4 0 Polycystin cation channel Forkhead PF00250.18 KER23534.1 - 0.29 11.4 2.0 16 5.9 0.1 3.0 3 0 0 3 3 3 0 Forkhead domain Tudor-knot PF11717.8 KER23534.1 - 0.46 10.4 6.2 77 3.3 0.1 4.7 5 0 0 5 5 5 0 RNA binding activity-knot of a chromodomain SH PF01445.17 KER23534.1 - 3 7.9 11.0 5.8 7.0 0.1 3.8 4 0 0 4 4 4 0 Viral small hydrophobic protein rve PF00665.26 KER23535.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain Sec16_C PF12931.7 KER23536.1 - 6.7e-24 85.1 0.0 1.3e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KER23536.1 - 0.0029 18.2 0.0 0.011 16.4 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region C2 PF00168.30 KER23537.1 - 1.7e-50 169.6 0.0 8.6e-14 51.7 0.0 6.4 5 1 0 5 5 5 5 C2 domain FerB PF08150.12 KER23537.1 - 5e-24 84.7 0.0 1.6e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 KER23537.1 - 9.7e-21 74.3 0.0 9.7e-21 74.3 0.0 4.0 3 1 1 4 4 4 2 Ferlin C-terminus FerI PF08151.12 KER23537.1 - 2.6e-15 56.2 0.0 1.5e-14 53.8 0.1 2.4 2 0 0 2 2 2 1 FerI (NUC094) domain DIL PF01843.19 KER23539.1 - 0.1 12.9 0.0 0.61 10.4 0.0 2.0 2 0 0 2 2 2 0 DIL domain PhoLip_ATPase_C PF16212.5 KER23540.1 - 2.4e-55 188.0 21.6 2.4e-55 188.0 21.6 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KER23540.1 - 2.3e-16 59.3 0.8 2.3e-16 59.3 0.8 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KER23540.1 - 2e-11 44.6 0.2 5.9e-06 26.7 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KER23540.1 - 1.8e-09 37.4 0.4 1.8e-09 37.4 0.4 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KER23540.1 - 2.4e-05 24.3 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF4079 PF13301.6 KER23540.1 - 0.048 13.8 0.2 8.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Hydrolase_3 PF08282.12 KER23540.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_M3 PF01432.20 KER23541.1 - 3.7e-13 49.6 0.0 2.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Innexin PF00876.18 KER23543.1 - 3.2e-102 342.4 1.5 3.7e-102 342.2 1.5 1.0 1 0 0 1 1 1 1 Innexin MULE PF10551.9 KER23545.1 - 3.3e-10 40.3 0.0 5.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain PAP2 PF01569.21 KER23545.1 - 1.4e-08 34.6 3.8 3.9e-08 33.1 3.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily RhoGEF PF00621.20 KER23546.1 - 1.6e-27 96.9 0.1 8.6e-27 94.5 0.0 2.4 2 0 0 2 2 2 1 RhoGEF domain Spectrin PF00435.21 KER23546.1 - 3.4e-18 66.1 35.8 1.3e-08 35.3 0.4 8.1 8 1 0 8 8 8 4 Spectrin repeat PH_10 PF15411.6 KER23546.1 - 0.00035 20.8 0.1 0.001 19.4 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER23546.1 - 0.00078 19.9 0.1 0.0037 17.7 0.1 2.3 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 KER23546.1 - 0.035 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain COG2 PF06148.11 KER23546.1 - 0.63 10.1 2.6 38 4.4 0.0 4.2 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.21 KER23546.1 - 3.2 7.6 7.5 3 7.6 4.0 2.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.11 KER23546.1 - 3.5 8.2 9.8 2.3 8.8 0.9 5.2 5 1 0 5 5 5 0 Syntaxin 6, N-terminal NA37 PF04245.13 KER23549.1 - 0.1 12.0 0.2 0.13 11.8 0.2 1.0 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein 7tm_1 PF00001.21 KER23551.1 - 2e-05 24.1 14.0 0.0016 17.8 2.2 3.2 3 1 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) DUF1030 PF06270.11 KER23551.1 - 0.084 12.6 1.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) DUF948 PF06103.11 KER23551.1 - 0.098 12.9 0.5 0.25 11.6 0.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5373 PF17343.2 KER23551.1 - 0.16 11.8 5.3 0.22 11.3 3.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Comm PF15957.5 KER23551.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.7 2 1 1 3 3 3 0 Commissureless DHHC PF01529.20 KER23551.1 - 0.56 10.3 12.0 0.18 11.9 4.3 3.2 3 1 0 3 3 3 0 DHHC palmitoyltransferase Integrase_H2C2 PF17921.1 KER23558.1 - 2.2e-07 30.9 0.1 5.2e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain BSP_II PF05432.11 KER23561.1 - 0.088 12.5 22.9 0.11 12.1 22.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_C13 PF01650.18 KER23562.1 - 1.9e-90 302.9 4.0 9.3e-89 297.3 4.0 2.1 1 1 0 1 1 1 1 Peptidase C13 family Peptidase_C25 PF01364.18 KER23562.1 - 0.0013 18.0 0.7 0.0079 15.4 0.9 2.0 1 1 0 1 1 1 1 Peptidase family C25 Peptidase_C14 PF00656.22 KER23562.1 - 0.0097 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Urm1 PF09138.11 KER23562.1 - 0.077 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Amidase_2 PF01510.25 KER23562.1 - 0.082 13.4 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase HLH PF00010.26 KER23568.1 - 3e-13 49.5 1.2 5.3e-13 48.7 1.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ING PF12998.7 KER23568.1 - 0.077 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF489 PF04356.12 KER23571.1 - 0.84 9.6 3.1 9.3 6.2 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) BTB_2 PF02214.22 KER23575.1 - 9.3e-20 70.8 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Metallophos PF00149.28 KER23576.1 - 1e-37 130.7 0.0 1.5e-37 130.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER23576.1 - 4.6e-10 39.8 0.2 8.8e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Yippee-Mis18 PF03226.14 KER23579.1 - 1.4e-10 41.3 0.2 2.2e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Exo_endo_phos_2 PF14529.6 KER23581.1 - 0.002 18.0 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LRR_9 PF14580.6 KER23582.1 - 6.6e-72 240.7 0.6 9.3e-72 240.2 0.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KER23582.1 - 1.7e-06 27.7 6.3 2.4e-05 24.0 2.4 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KER23582.1 - 0.00013 22.2 9.3 0.015 15.7 1.2 3.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) SUIM_assoc PF16619.5 KER23582.1 - 0.027 14.5 7.4 0.061 13.4 7.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LRR_6 PF13516.6 KER23582.1 - 9.9 6.5 6.3 1.5e+02 2.8 0.4 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Homeodomain PF00046.29 KER23584.1 - 7.9e-24 83.3 0.1 1.5e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER23584.1 - 0.00057 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain LRR_4 PF12799.7 KER23585.1 - 7e-07 29.5 2.1 0.0032 17.8 0.2 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER23585.1 - 0.00089 19.0 1.7 0.007 16.1 0.2 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 KER23585.1 - 0.03 13.8 1.6 1.6 8.2 0.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeat zf-C2H2_assoc PF16606.5 KER23585.1 - 2.6 8.3 7.5 0.32 11.2 1.9 2.3 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Collagen PF01391.18 KER23590.1 - 2.2e-162 526.9 626.9 3.3e-10 39.6 23.8 21.2 2 1 10 12 12 12 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER23590.1 - 1.8e-23 83.1 0.1 6.4e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Fibrillar collagen C-terminal domain Laminin_G_3 PF13385.6 KER23590.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily LRR_8 PF13855.6 KER23594.1 - 1.5e-26 91.9 16.4 3e-08 33.3 1.1 7.8 7 1 0 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KER23594.1 - 2.3e-12 46.9 21.5 5.9e-05 23.3 1.1 8.3 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER23594.1 - 1.4e-05 24.7 2.5 0.00023 20.7 0.1 3.7 5 0 0 5 5 5 1 Leucine-rich repeat LRR_5 PF13306.6 KER23594.1 - 0.00033 20.6 0.0 0.66 9.9 0.0 4.0 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KER23594.1 - 0.0025 18.1 13.6 11 7.1 0.1 8.2 9 0 0 9 9 9 2 Leucine Rich Repeat RCR PF12273.8 KER23594.1 - 0.16 12.6 0.0 0.16 12.6 0.0 3.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red ABC_tran PF00005.27 KER23595.1 - 1.1e-34 119.8 2.7 1.8e-22 80.3 0.0 3.4 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 KER23595.1 - 3.2e-25 88.0 2.5 3.2e-25 88.0 2.5 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KER23595.1 - 2.1e-14 54.1 0.8 6.2e-06 26.2 0.0 3.5 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER23595.1 - 9.2e-09 35.1 0.2 0.0013 18.2 0.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RVT_1 PF00078.27 KER23595.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_15 PF13175.6 KER23595.1 - 0.00077 19.3 0.4 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KER23595.1 - 0.0014 19.0 0.2 0.0063 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KER23595.1 - 0.0019 18.7 4.3 0.0057 17.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KER23595.1 - 0.0037 17.5 0.2 0.019 15.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KER23595.1 - 0.0047 17.1 0.6 0.42 10.9 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KER23595.1 - 0.0072 16.3 0.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 KER23595.1 - 0.0096 16.0 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 KER23595.1 - 0.019 14.0 0.0 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 KER23595.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KER23595.1 - 0.042 13.8 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KER23595.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KER23595.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KER23595.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KER23595.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ARPC4 PF05856.12 KER23597.1 - 0.099 12.2 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Neur_chan_LBD PF02931.23 KER23598.1 - 9.3e-37 126.6 0.3 1.3e-36 126.1 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER23598.1 - 1.1e-17 64.9 0.0 1.4e-15 58.0 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4124 PF13511.6 KER23598.1 - 0.089 13.1 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) WD40 PF00400.32 KER23601.1 - 1.2e-14 54.4 6.3 0.00027 21.7 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER23601.1 - 6.9e-07 29.5 0.0 0.0003 21.0 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 KER23601.1 - 0.0005 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER23603.1 - 4.6e-40 137.6 1.0 8.2e-40 136.8 1.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23603.1 - 1.6e-29 103.0 0.4 3.6e-29 101.8 0.4 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER23603.1 - 0.0019 17.1 0.1 0.0042 15.9 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase BACK PF07707.15 KER23606.1 - 1.1e-06 28.7 0.2 7.8e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 KER23606.1 - 6.9e-06 26.3 1.8 0.00012 22.3 0.9 2.7 2 1 0 2 2 2 1 BTB/POZ domain Rx_N PF18052.1 KER23608.1 - 0.13 12.5 3.4 1.1 9.6 2.7 3.2 1 1 0 1 1 1 0 Rx N-terminal domain Kinesin PF00225.23 KER23610.1 - 3.7e-44 151.0 6.8 4.6e-44 150.7 6.8 1.1 1 0 0 1 1 1 1 Kinesin motor domain FAM76 PF16046.5 KER23610.1 - 0.00012 21.5 0.4 0.00018 21.0 0.4 1.2 1 0 0 1 1 1 1 FAM76 protein Kinesin PF00225.23 KER23611.1 - 1.1e-17 64.1 0.3 1.1e-17 64.0 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER23611.1 - 3.4e-11 43.3 0.1 3.7e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Microtubule binding PhoH PF02562.16 KER23611.1 - 0.021 14.3 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 KER23611.1 - 0.034 13.3 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase Methyltransf_17 PF12692.7 KER23611.1 - 0.034 14.2 0.1 0.035 14.1 0.1 1.2 1 1 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase RVT_1 PF00078.27 KER23612.1 - 4.5e-15 55.8 0.0 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.23 KER23613.1 - 6.5e-10 39.1 0.0 9.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER23613.1 - 0.024 14.2 0.1 0.083 12.4 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.13 KER23613.1 - 0.027 13.5 0.5 0.039 13.0 0.5 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KER23613.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KER23613.1 - 0.15 11.8 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Toxin_TOLIP PF00087.21 KER23615.1 - 0.0027 17.9 0.2 0.0041 17.3 0.2 1.3 1 0 0 1 1 1 1 Snake toxin and toxin-like protein Defensin_RK-1 PF17860.1 KER23615.1 - 0.67 10.5 6.8 15 6.1 6.8 2.3 1 1 0 1 1 1 0 RK-1-like defensin Aldedh PF00171.22 KER23616.1 - 9.1e-119 397.0 0.0 7.2e-97 324.8 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DAP3 PF10236.9 KER23616.1 - 6.8e-34 117.4 0.0 1.2e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Ank_2 PF12796.7 KER23617.1 - 3.2e-38 130.2 3.3 2.2e-08 34.6 0.0 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER23617.1 - 6.8e-34 115.8 16.4 1.4e-06 28.7 0.1 9.2 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KER23617.1 - 7.3e-31 105.2 14.3 0.0006 20.1 0.1 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 KER23617.1 - 2.6e-25 85.7 15.3 0.028 14.9 0.1 10.8 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KER23617.1 - 2.6e-17 62.6 15.8 3.6e-07 30.3 0.2 8.8 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Biopterin_H PF00351.21 KER23619.1 - 2e-104 349.3 0.1 2.3e-101 339.2 0.0 2.3 1 1 1 2 2 2 2 Biopterin-dependent aromatic amino acid hydroxylase RICTOR_N PF14664.6 KER23620.1 - 7e-13 48.3 7.0 3.2e-07 29.7 0.2 3.4 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KER23620.1 - 5.1e-10 39.0 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KER23620.1 - 1.1e-07 32.0 1.3 1.9e-06 28.0 0.4 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Imm40 PF15569.6 KER23623.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 40 QVR PF17064.5 KER23624.1 - 0.01 16.1 10.4 0.013 15.7 10.4 1.1 1 0 0 1 1 1 0 Sleepless protein LLC1 PF14945.6 KER23625.1 - 8.3e-26 90.9 0.3 9.5e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein GCFC PF07842.12 KER23626.1 - 5.8e-21 75.3 0.5 5.7e-20 72.1 0.5 2.3 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Cas_Csy4 PF09618.10 KER23626.1 - 0.27 11.4 3.1 31 4.6 0.0 2.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Draxin PF15550.6 KER23626.1 - 0.82 9.5 11.8 0.088 12.7 0.9 2.6 2 1 0 2 2 2 0 Draxin Fcf2 PF08698.11 KER23628.1 - 2.1e-22 79.3 1.1 4.4e-22 78.3 0.4 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing DUF4790 PF16037.5 KER23628.1 - 0.28 11.7 3.7 0.41 11.1 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4790) Methyltransf_23 PF13489.6 KER23629.1 - 1.2e-15 57.7 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER23629.1 - 2.6e-12 47.3 0.0 5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER23629.1 - 3.4e-12 47.0 0.0 5.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER23629.1 - 5.4e-09 36.6 0.0 9.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER23629.1 - 5.9e-06 26.2 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KER23629.1 - 0.00014 21.3 0.0 0.00081 18.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KER23629.1 - 0.0023 17.4 0.0 0.0052 16.2 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 KER23629.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 KER23630.1 - 8.5e-14 51.1 0.0 6.6e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndufs5 PF10200.9 KER23631.1 - 1.8e-08 34.5 0.1 3.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa QSregVF_b PF12843.7 KER23631.1 - 0.13 12.2 2.3 0.3 11.0 1.0 2.2 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor DHC_N2 PF08393.13 KER23634.1 - 3.3e-154 513.8 22.9 2.6e-120 402.2 4.2 4.6 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KER23634.1 - 1.2e-142 474.7 0.0 2.3e-142 473.8 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KER23634.1 - 5.2e-127 424.8 8.1 5.2e-127 424.8 8.1 3.2 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 KER23634.1 - 1.9e-11 44.1 0.0 2.7e-07 30.7 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 KER23634.1 - 2e-05 25.0 0.2 0.097 13.1 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KER23634.1 - 9.6e-05 22.0 0.3 0.011 15.3 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region BLM10_N PF16547.5 KER23634.1 - 0.00093 19.4 0.9 2.6 8.4 0.1 3.0 3 0 0 3 3 3 2 Proteasome-substrate-size regulator, N-terminal AAA_16 PF13191.6 KER23634.1 - 0.0076 16.6 0.0 1.1 9.6 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 KER23634.1 - 0.0098 16.2 0.2 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KER23634.1 - 0.045 14.0 0.1 3.2 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KER23634.1 - 0.067 13.6 0.1 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KER23634.1 - 0.078 12.7 0.6 7 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KER23634.1 - 0.16 10.9 0.9 0.46 9.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 KER23634.1 - 0.19 11.9 0.1 9.7 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain FliT PF05400.13 KER23634.1 - 0.77 10.6 9.2 60 4.6 0.4 4.5 3 0 0 3 3 3 0 Flagellar protein FliT Dynein_C PF18199.1 KER23635.1 - 1.8e-93 313.1 0.0 8.4e-38 130.3 0.0 3.8 1 1 2 3 3 3 3 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KER23635.1 - 2.7e-90 302.2 0.0 5.8e-90 301.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER23635.1 - 1.5e-84 282.5 2.2 6.6e-84 280.4 2.2 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER23635.1 - 9.9e-62 207.7 0.3 1.3e-60 204.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER23635.1 - 1.1e-49 168.4 0.0 3e-49 167.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER23635.1 - 2.9e-46 158.1 1.8 2.9e-46 158.1 1.8 1.9 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 KER23635.1 - 6.7e-17 61.5 0.0 5.7e-16 58.6 0.0 2.6 3 0 0 3 3 3 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KER23635.1 - 2e-14 53.7 0.2 7.3e-11 42.3 0.0 3.2 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER23635.1 - 2.6e-08 33.9 1.5 0.00052 20.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER23635.1 - 0.013 15.7 0.6 0.17 12.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain TniB PF05621.11 KER23635.1 - 0.035 13.5 0.2 0.66 9.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_16 PF13191.6 KER23635.1 - 0.065 13.6 3.5 0.62 10.4 0.0 3.6 3 1 1 4 4 3 0 AAA ATPase domain PDEase_I_N PF08499.12 KER23635.1 - 0.17 11.8 0.4 48 3.9 0.0 3.3 3 0 0 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal LIF_OSM PF01291.17 KER23635.1 - 1.5 8.9 4.3 9.1 6.4 0.2 3.4 3 0 0 3 3 3 0 LIF / OSM family TPR_MLP1_2 PF07926.12 KER23635.1 - 7.2 6.7 33.0 0.19 11.8 5.3 3.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cyt-b5 PF00173.28 KER23636.1 - 4e-23 81.4 0.1 7.7e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDCD9 PF07147.12 KER23636.1 - 2.1e-09 37.1 0.0 3.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) rve PF00665.26 KER23637.1 - 2.6e-15 56.7 0.0 9.7e-15 54.8 0.0 1.9 2 1 1 3 3 3 1 Integrase core domain rve_3 PF13683.6 KER23637.1 - 8.2e-06 25.5 0.1 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 KER23637.1 - 0.063 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Globin PF00042.22 KER23638.1 - 2.1e-11 44.3 0.0 3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 KER23638.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Protoglobin Y_phosphatase2 PF03162.13 KER23638.1 - 0.034 13.7 0.2 0.043 13.4 0.2 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DnaJ PF00226.31 KER23639.1 - 1.5e-19 69.9 0.9 7.6e-19 67.6 0.9 2.3 2 0 0 2 2 2 1 DnaJ domain SAE2 PF08573.10 KER23639.1 - 0.02 16.0 2.0 0.039 15.1 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TSSC4 PF15264.6 KER23639.1 - 1.7 8.9 7.7 54 4.1 0.1 4.0 3 1 1 4 4 4 0 Tumour suppressing sub-chromosomal transferable candidate 4 Globin PF00042.22 KER23640.1 - 1.6e-10 41.5 0.1 3.4e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Globin CTD_bind PF04818.13 KER23642.1 - 0.00039 21.2 0.2 0.00079 20.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KER23642.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Gtr1_RagA PF04670.12 KER23644.1 - 4.8e-26 91.5 0.0 9.2e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 KER23645.1 - 1.8e-07 30.9 0.0 5.2e-07 29.4 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2408 PF10303.9 KER23645.1 - 0.052 14.1 0.6 0.083 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-C2H2 PF00096.26 KER23647.1 - 7.7e-48 158.4 190.4 0.00012 22.3 2.2 23.1 22 0 0 22 22 22 20 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER23647.1 - 1.3e-43 143.8 187.1 0.00014 22.4 1.2 22.8 22 0 0 22 22 22 20 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER23647.1 - 2.5e-18 65.6 162.9 7.7e-06 26.1 2.7 23.9 25 1 1 26 26 25 11 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER23647.1 - 1.1e-08 35.1 93.2 0.0034 17.6 0.1 19.5 21 0 0 21 21 21 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER23647.1 - 6.5e-07 29.5 122.6 0.04 14.3 0.1 19.5 20 0 0 20 20 20 10 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER23647.1 - 1.4e-05 25.2 126.5 0.04 14.2 0.2 14.6 12 2 3 15 15 13 8 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KER23647.1 - 0.0026 18.4 1.0 0.0026 18.4 1.0 11.3 7 4 5 13 13 13 2 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 KER23647.1 - 0.0036 17.7 43.3 0.12 12.8 0.1 9.8 10 0 0 10 10 9 3 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KER23647.1 - 0.004 17.1 0.5 0.004 17.1 0.5 18.2 21 0 0 21 21 20 6 C2H2-type zinc finger S8_pro-domain PF16470.5 KER23647.1 - 0.011 16.5 0.6 0.042 14.6 0.6 2.1 1 0 0 1 1 1 0 Peptidase S8 pro-domain Rad50_zn_hook PF04423.14 KER23647.1 - 0.022 14.6 24.5 0.58 10.0 0.1 7.4 7 1 1 8 8 8 0 Rad50 zinc hook motif DUF4428 PF14471.6 KER23647.1 - 0.056 13.4 0.2 0.056 13.4 0.2 7.2 7 2 1 8 8 8 0 Domain of unknown function (DUF4428) zf-C2HC_2 PF13913.6 KER23647.1 - 0.081 12.8 0.2 0.081 12.8 0.2 11.8 13 0 0 13 13 12 0 zinc-finger of a C2HC-type DUF1324 PF07038.11 KER23648.1 - 0.006 16.8 0.1 0.18 12.1 0.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1324) GYF PF02213.16 KER23649.1 - 1.3e-12 47.1 0.0 2.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 GYF domain Mfp-3 PF04202.13 KER23650.1 - 0.039 14.3 0.1 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 Foot protein 3 GPCR_chapero_1 PF11904.8 KER23652.1 - 3.8e-88 295.9 0.0 5.3e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_5 PF13857.6 KER23652.1 - 4.9e-08 33.1 0.2 5.8e-05 23.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER23652.1 - 1.4e-07 32.0 0.0 6.1e-07 29.9 0.1 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KER23652.1 - 2.1e-06 27.9 0.9 0.0022 18.3 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KER23652.1 - 1.1e-05 25.4 0.1 0.0027 18.1 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KER23652.1 - 0.0062 17.1 0.1 0.18 12.5 0.0 3.0 2 1 0 3 3 3 1 Ankyrin repeats (many copies) UIM PF02809.20 KER23652.1 - 8.3 6.6 19.7 0.063 13.2 1.1 3.7 4 0 0 4 4 4 0 Ubiquitin interaction motif Actin PF00022.19 KER23653.1 - 6.5e-18 64.5 0.0 8.4e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Actin Dynein_light PF01221.18 KER23654.1 - 8.4e-10 38.8 0.6 1.3e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Dynein light chain type 1 Dynein_light PF01221.18 KER23655.1 - 1.4e-06 28.5 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER23655.1 - 0.059 13.8 0.1 0.082 13.4 0.1 1.5 1 1 0 1 1 1 0 EF-hand domain pair Dynein_light PF01221.18 KER23656.1 - 4.8e-09 36.4 0.0 7.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 KER23656.1 - 3.4e-07 29.3 0.1 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23656.1 - 4.9e-06 26.1 0.1 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER23656.1 - 6.5e-06 26.5 0.0 2.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 KER23656.1 - 0.046 14.1 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain Dynein_light PF01221.18 KER23657.1 - 2e-11 44.1 0.0 2.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 KER23657.1 - 0.012 15.2 1.1 0.02 14.4 0.1 1.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KER23657.1 - 0.026 14.4 0.2 0.054 13.4 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair HTH_31 PF13560.6 KER23657.1 - 0.12 12.8 0.0 8.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain EF-hand_6 PF13405.6 KER23657.1 - 0.16 12.0 1.6 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KER23658.1 - 3.1e-09 37.1 0.4 6.3e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER23658.1 - 6.4e-08 31.6 0.5 0.011 15.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23658.1 - 1.1e-07 31.1 0.3 0.016 15.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KER23658.1 - 0.0021 17.9 0.3 0.039 13.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KER23658.1 - 0.0021 17.5 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 EF hand rve PF00665.26 KER23658.1 - 0.056 13.6 0.1 9.4 6.5 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain Dynein_light PF01221.18 KER23659.1 - 1.6e-18 66.8 0.7 2e-18 66.5 0.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_1 PF00036.32 KER23659.1 - 0.0031 16.9 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KER23659.1 - 0.0098 15.7 0.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KER23659.1 - 0.01 15.7 0.9 0.017 15.0 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Tox-REase-9 PF15650.6 KER23659.1 - 0.016 15.5 0.0 0.51 10.7 0.0 2.1 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 9 EF-hand_7 PF13499.6 KER23659.1 - 0.1 13.1 0.5 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Apolipoprotein PF01442.18 KER23659.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1697 PF08002.11 KER23659.1 - 0.11 13.0 0.0 0.45 11.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1697) Ground-like PF04155.18 KER23659.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.5 1 1 0 1 1 1 0 Ground-like domain YopE_N PF09020.10 KER23661.1 - 0.00031 21.0 0.9 1.3 9.2 0.1 2.8 3 0 0 3 3 3 2 YopE, N terminal Toxin_27 PF08099.11 KER23661.1 - 1.4 9.1 7.5 11 6.2 0.9 2.4 2 0 0 2 2 2 0 Scorpion calcine family KH_1 PF00013.29 KER23662.1 - 9.3e-25 86.3 0.9 7.2e-13 48.2 0.4 2.9 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 KER23662.1 - 3e-08 33.4 0.7 0.00059 19.6 0.1 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KER23662.1 - 0.00022 21.1 0.1 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KER23662.1 - 0.38 10.9 3.2 7 6.8 0.3 2.4 2 0 0 2 2 2 0 NusA-like KH domain GRIP PF01465.20 KER23663.1 - 0.0033 17.3 0.1 0.0086 16.0 0.1 1.7 1 0 0 1 1 1 1 GRIP domain Rhomboid PF01694.22 KER23664.1 - 0.0004 20.4 4.0 0.00043 20.3 4.0 1.1 1 0 0 1 1 1 1 Rhomboid family DUF4218 PF13960.6 KER23665.1 - 7e-05 22.4 0.1 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) LRR_6 PF13516.6 KER23666.1 - 1.6e-16 58.9 12.4 0.013 15.5 0.3 7.9 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 KER23666.1 - 2.9e-07 30.7 14.5 0.021 15.2 1.3 5.5 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER23666.1 - 0.00055 20.1 11.5 43 5.2 0.0 7.6 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 KER23666.1 - 0.0017 18.1 14.0 0.27 11.0 0.6 5.4 5 1 1 6 6 6 2 Leucine rich repeat SDA1 PF05285.12 KER23666.1 - 1.5 8.1 15.9 2.7 7.3 15.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER23666.1 - 2.3 7.5 15.5 0.47 9.7 12.2 1.4 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KER23666.1 - 6.2 4.9 14.8 9.2 4.3 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KER23666.1 - 8.3 4.4 15.7 18 3.2 15.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi TMEM154 PF15102.6 KER23667.1 - 0.0074 16.2 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family Orf78 PF06024.12 KER23667.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 KER23667.1 - 0.099 13.5 0.1 0.21 12.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 KER23667.1 - 0.12 13.1 0.5 0.45 11.3 0.2 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF1640 PF07798.11 KER23668.1 - 0.0077 16.3 1.7 0.016 15.3 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Metal_resist PF13801.6 KER23668.1 - 0.19 11.9 7.9 0.055 13.7 4.0 1.9 2 0 0 2 2 2 0 Heavy-metal resistance OmpH PF03938.14 KER23668.1 - 0.23 11.8 3.2 0.56 10.5 3.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DLP_helical PF18709.1 KER23668.1 - 0.33 10.1 2.6 0.5 9.5 2.6 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain UPF0086 PF01868.16 KER23669.1 - 0.07 13.1 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function UPF0086 Torsin PF06309.11 KER23670.1 - 6.8e-38 129.6 2.6 1.1e-37 128.9 2.6 1.4 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 KER23670.1 - 0.0099 16.3 0.1 4.8 7.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 KER23670.1 - 0.022 14.8 0.1 4 7.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 KER23670.1 - 0.039 14.4 0.0 0.086 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER23670.1 - 0.092 13.0 0.0 0.68 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain Marek_A PF02124.15 KER23671.1 - 0.08 12.8 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A EGF PF00008.27 KER23672.1 - 3.2e-07 30.5 39.0 0.0096 16.2 3.8 4.1 2 1 2 4 4 4 3 EGF-like domain EGF_CA PF07645.15 KER23672.1 - 7e-07 29.3 26.2 0.002 18.3 5.3 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain hEGF PF12661.7 KER23672.1 - 4.2e-06 27.2 37.3 0.0086 16.7 8.2 3.7 3 0 0 3 3 3 3 Human growth factor-like EGF cEGF PF12662.7 KER23672.1 - 4.1e-05 23.4 26.7 0.00064 19.6 1.0 4.3 5 0 0 5 5 5 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 KER23672.1 - 4.5e-05 23.6 31.9 0.083 13.2 7.1 3.4 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 KER23672.1 - 0.11 12.8 14.1 1.5 9.2 0.2 3.3 3 0 0 3 3 3 0 Pvs28 EGF domain EGF_3 PF12947.7 KER23672.1 - 0.18 12.0 15.5 9.3 6.5 1.8 3.6 3 0 0 3 3 3 0 EGF domain EGF_2 PF07974.13 KER23672.1 - 0.75 10.2 27.8 4.2 7.8 4.1 3.5 3 0 0 3 3 3 0 EGF-like domain TB PF00683.17 KER23673.1 - 7.4e-06 25.6 2.1 7.4e-06 25.6 2.1 3.4 3 1 0 3 3 3 1 TB domain EGF_2 PF07974.13 KER23673.1 - 0.00054 20.3 12.0 0.00054 20.3 12.0 5.0 5 1 0 5 5 5 2 EGF-like domain EGF_Tenascin PF18720.1 KER23673.1 - 0.011 15.8 12.5 0.011 15.8 12.5 5.0 5 1 0 5 5 5 0 Tenascin EGF domain Hexokinase_2 PF03727.16 KER23675.1 - 2.6e-44 151.4 0.0 4.9e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KER23675.1 - 1.8e-29 103.1 3.7 2.5e-23 83.0 0.0 3.0 2 1 1 3 3 3 2 Hexokinase RVT_1 PF00078.27 KER23675.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SBP_bac_5 PF00496.22 KER23675.1 - 0.21 10.5 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle EcoEI_R_C PF08463.10 KER23675.1 - 0.35 11.0 2.6 0.37 10.9 0.3 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal ThiF PF00899.21 KER23678.1 - 2.8e-114 380.6 0.0 7.1e-77 258.1 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KER23678.1 - 3.1e-88 295.9 0.0 5e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KER23678.1 - 1.4e-33 115.4 0.0 2.8e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KER23678.1 - 3.2e-33 113.7 0.5 1e-32 112.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KER23678.1 - 1.3e-21 76.6 0.3 3.4e-21 75.2 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle PhoD PF09423.10 KER23682.1 - 0.091 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase 7tm_1 PF00001.21 KER23683.1 - 3.8e-51 173.9 10.5 5.6e-51 173.4 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER23683.1 - 5.9e-06 25.9 11.0 5.9e-06 25.9 11.0 3.0 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER23683.1 - 7.7e-06 25.7 19.5 7.7e-06 25.7 19.5 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Tmemb_9 PF05434.11 KER23683.1 - 0.00015 21.7 2.0 0.45 10.4 0.1 3.1 3 0 0 3 3 3 2 TMEM9 7tm_4 PF13853.6 KER23683.1 - 0.00045 20.0 19.8 0.023 14.4 15.3 2.6 2 1 1 3 3 3 2 Olfactory receptor DUF4834 PF16118.5 KER23683.1 - 0.18 12.8 0.0 1 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1980 PF09323.10 KER23683.1 - 0.35 10.8 6.0 0.19 11.6 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) RGS_DHEX PF18148.1 KER23688.1 - 4.7e-39 132.5 0.1 1e-38 131.5 0.1 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 KER23688.1 - 2.4e-29 102.0 0.2 4.7e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KER23688.1 - 3.2e-18 65.5 0.0 9.8e-18 64.0 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 KER23688.1 - 0.0024 17.8 2.4 0.003 17.5 0.0 2.4 3 0 0 3 3 3 1 GGL domain Slx4 PF09494.10 KER23688.1 - 0.055 13.4 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Slx4 endonuclease RGS-like PF09128.11 KER23688.1 - 0.069 12.9 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain SET PF00856.28 KER23689.1 - 0.048 14.0 0.0 0.2 12.0 0.0 2.0 3 0 0 3 3 3 0 SET domain DUF4322 PF14210.6 KER23691.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) RVT_1 PF00078.27 KER23692.1 - 1.6e-22 80.1 0.0 2.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.21 KER23692.1 - 2.7e-22 79.4 11.6 7.9e-22 77.8 11.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2567 PF10821.8 KER23692.1 - 0.49 10.5 5.5 0.17 12.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) DUF4834 PF16118.5 KER23692.1 - 0.86 10.6 2.8 11 7.0 2.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TIMP PF00965.17 KER23694.1 - 3.8e-15 56.2 3.5 7.6e-15 55.2 3.5 1.5 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Zip PF02535.22 KER23695.1 - 4.5e-19 68.9 0.5 7.1e-19 68.2 0.5 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter EutH PF04346.12 KER23695.1 - 0.0054 16.0 0.2 0.0056 15.9 0.2 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein, EutH DUF2427 PF10348.9 KER23695.1 - 0.0063 16.3 0.4 0.0091 15.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) ALG3 PF05208.13 KER23697.1 - 1.7e-128 429.1 24.8 2.2e-128 428.7 24.8 1.2 1 0 0 1 1 1 1 ALG3 protein OTU PF02338.19 KER23698.1 - 3.3e-14 53.5 0.0 6.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 KER23698.1 - 9.4e-09 34.4 37.0 0.00016 20.9 7.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others AnkUBD PF18418.1 KER23698.1 - 9.4e-06 25.7 0.0 0.067 13.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin ubiquitin-binding domain DZR PF12773.7 KER23698.1 - 0.00024 21.1 19.1 0.041 13.9 12.8 2.9 1 1 2 3 3 3 3 Double zinc ribbon Kinesin PF00225.23 KER23699.1 - 5.5e-99 331.2 6.3 2.4e-89 299.5 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KER23699.1 - 1.3e-15 57.6 1.2 4.3e-11 43.0 0.0 3.6 2 1 0 2 2 2 2 Microtubule binding APG6_N PF17675.1 KER23699.1 - 4.4 7.8 30.1 0.18 12.3 4.4 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region Hrs_helical PF12210.8 KER23702.1 - 1.6e-38 131.1 5.3 1.6e-38 131.1 5.3 2.3 1 1 1 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate NDK PF00334.19 KER23703.1 - 1.5e-39 135.1 0.0 2.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 KER23703.1 - 8.6e-18 63.8 0.2 1.4e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 Dpy-30 motif Rep_N PF08724.10 KER23703.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Rep protein catalytic domain like zf-RING_9 PF13901.6 KER23704.1 - 7.4e-32 111.0 4.9 7.4e-32 111.0 4.9 2.6 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KER23704.1 - 1.5e-05 24.8 4.4 1.5e-05 24.8 4.4 4.2 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Mac PF12464.8 KER23704.1 - 0.59 10.4 4.2 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 Maltose acetyltransferase DCP2 PF05026.13 KER23705.1 - 1.3e-15 57.4 0.4 3.2e-15 56.2 0.4 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KER23705.1 - 4.6e-14 52.6 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain SPX PF03105.19 KER23708.1 - 4 7.3 11.5 4.4 7.1 11.5 1.1 1 0 0 1 1 1 0 SPX domain IQ PF00612.27 KER23710.1 - 0.13 12.1 3.6 0.36 10.8 3.6 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cnl2_NKP2 PF09447.10 KER23710.1 - 0.14 12.3 9.6 0.84 9.8 0.4 3.9 2 1 1 3 3 3 0 Cnl2/NKP2 family protein KAP PF05804.12 KER23711.1 - 8.3e-220 731.6 22.9 4.7e-147 491.2 9.2 3.3 2 1 1 3 3 3 3 Kinesin-associated protein (KAP) Arm PF00514.23 KER23711.1 - 0.00019 21.4 0.0 8.5 6.6 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RhoGAP PF00620.27 KER23711.1 - 0.12 12.2 2.2 0.93 9.3 0.2 3.2 3 0 0 3 3 3 0 RhoGAP domain Cnd1 PF12717.7 KER23711.1 - 0.24 11.4 4.4 8 6.5 0.0 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DBINO PF13892.6 KER23712.1 - 0.0067 16.8 1.8 0.011 16.1 1.8 1.3 1 0 0 1 1 1 1 DNA-binding domain Frizzled PF01534.17 KER23713.1 - 2.2e-101 339.2 23.1 1.3e-79 267.6 12.5 2.2 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region Fz PF01392.22 KER23713.1 - 8.7e-29 100.4 5.8 1.7e-28 99.5 5.8 1.5 1 0 0 1 1 1 1 Fz domain OSTMP1 PF09777.9 KER23714.1 - 6.4e-29 101.0 6.3 1e-21 77.4 2.5 3.2 1 1 1 2 2 2 2 Osteopetrosis-associated transmembrane protein 1 precursor DUF1072 PF06380.11 KER23714.1 - 1.2 9.1 7.3 8.6 6.3 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1072) Stk19 PF10494.9 KER23715.1 - 4.9e-24 85.3 0.7 1.5e-23 83.8 0.7 1.7 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 BLACT_WH PF17778.1 KER23715.1 - 0.14 12.1 0.2 0.42 10.6 0.2 1.8 1 1 0 1 1 1 0 Beta-lactamase associated winged helix domain WD40 PF00400.32 KER23716.1 - 6e-07 30.1 13.6 0.47 11.4 0.6 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Lectin_C PF00059.21 KER23716.1 - 0.00043 21.0 0.0 0.0015 19.3 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain Nup160 PF11715.8 KER23716.1 - 0.022 13.4 0.1 0.034 12.8 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Dor1 PF04124.12 KER23717.1 - 1.4e-61 208.0 4.5 7.9e-47 159.6 1.5 3.3 3 0 0 3 3 3 3 Dor1-like family Zw10 PF06248.13 KER23717.1 - 0.00044 19.0 0.1 0.00085 18.0 0.1 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.12 KER23717.1 - 0.11 12.6 2.4 4.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 KER23717.1 - 0.13 12.3 1.0 0.31 11.1 1.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 KER23718.1 - 2.4e-40 137.3 175.1 3.3e-10 40.4 4.0 28.0 24 5 2 28 28 28 11 Spectrin repeat GAS2 PF02187.17 KER23718.1 - 9.5e-30 102.5 0.5 9.5e-30 102.5 0.5 2.2 2 0 0 2 2 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.32 KER23718.1 - 6.2e-08 31.7 0.3 0.0024 17.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER23718.1 - 2.4e-07 30.2 0.5 0.0037 17.1 0.0 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER23718.1 - 3.8e-07 30.5 1.6 2.6e-06 27.8 0.5 3.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KER23718.1 - 0.00062 19.2 1.2 0.7 9.5 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER23718.1 - 0.0015 18.3 0.3 3.5 7.5 0.0 3.2 1 1 1 2 2 2 2 EF-hand domain pair Rop PF01815.16 KER23718.1 - 0.042 13.7 0.2 23 5.0 0.0 3.6 2 0 0 2 2 2 0 Rop protein Corona_5a PF06336.11 KER23718.1 - 0.045 13.7 0.2 0.15 12.0 0.2 1.9 1 0 0 1 1 1 0 Coronavirus 5a protein Transcrip_act PF04949.13 KER23718.1 - 0.079 12.8 7.8 0.3 11.0 0.1 5.7 4 0 0 4 4 4 0 Transcriptional activator Bcr-Abl_Oligo PF09036.10 KER23718.1 - 0.083 12.9 0.9 3.6 7.7 0.1 4.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Complex1_LYR_2 PF13233.6 KER23718.1 - 0.29 11.9 2.9 1.8 9.3 0.2 4.1 2 0 0 2 2 1 0 Complex1_LYR-like Goodbye PF17109.5 KER23718.1 - 3.2 8.2 8.4 19 5.7 0.2 6.5 5 0 0 5 5 5 0 fungal STAND N-terminal Goodbye domain SIR2 PF02146.17 KER23719.1 - 5.3e-60 202.3 0.0 8.5e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KER23719.1 - 0.0004 20.1 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KER23719.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF592) 7tm_1 PF00001.21 KER23722.1 - 6.8e-47 160.0 20.8 9e-28 97.3 6.8 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER23722.1 - 9.4e-10 38.3 17.2 1.4e-06 27.9 7.9 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zf-LITAF-like PF10601.9 KER23722.1 - 0.0056 16.9 5.7 2.3 8.5 0.3 3.7 3 0 0 3 3 3 2 LITAF-like zinc ribbon domain 7tm_4 PF13853.6 KER23722.1 - 0.0085 15.9 6.0 0.0085 15.9 6.0 2.1 2 0 0 2 2 2 1 Olfactory receptor Phage_holin_3_6 PF07332.11 KER23722.1 - 5.5 7.1 12.4 6.9 6.8 0.0 3.7 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Aldo_ket_red PF00248.21 KER23724.1 - 3.3e-32 111.9 0.0 4.8e-25 88.3 0.0 2.8 2 1 0 2 2 2 2 Aldo/keto reductase family MENTAL PF10457.9 KER23728.1 - 1.6e-51 174.7 1.4 1.6e-51 174.7 1.4 1.6 2 0 0 2 2 2 1 Cholesterol-capturing domain START PF01852.19 KER23728.1 - 2.6e-19 69.5 0.0 5.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 START domain CPP1-like PF11833.8 KER23728.1 - 0.27 10.9 1.1 0.48 10.1 1.1 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SH PF01445.17 KER23728.1 - 3 7.9 6.2 0.43 10.6 1.2 2.2 2 0 0 2 2 2 0 Viral small hydrophobic protein RBM39linker PF15519.6 KER23730.1 - 1.5 10.0 5.6 0.45 11.6 1.6 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Beach PF02138.18 KER23732.1 - 1.1e-118 395.6 0.0 2.7e-118 394.4 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KER23732.1 - 2.5e-14 53.2 0.0 8.5e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 KER23732.1 - 8.4e-12 44.9 0.0 1.2e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4800) DUF4704 PF15787.5 KER23732.1 - 5e-05 22.7 15.6 8.7e-05 21.9 3.4 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF4704) YGGT PF02325.17 KER23732.1 - 0.054 13.9 0.1 0.21 12.0 0.1 2.1 1 0 0 1 1 1 0 YGGT family WD40 PF00400.32 KER23732.1 - 1.3 10.1 4.2 26 5.9 0.1 4.1 3 0 0 3 3 3 0 WD domain, G-beta repeat CENP-B_dimeris PF09026.10 KER23734.1 - 0.0015 18.8 10.3 0.0018 18.6 10.3 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KER23734.1 - 0.065 13.6 10.0 0.087 13.2 10.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAF1-p150_C2 PF15539.6 KER23734.1 - 0.093 12.2 3.7 0.11 12.0 3.7 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term TFIIF_alpha PF05793.12 KER23734.1 - 0.43 9.1 5.8 0.47 9.0 5.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ANAPC9 PF12856.7 KER23734.1 - 1 9.6 4.4 1.4 9.2 4.4 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Utp14 PF04615.13 KER23734.1 - 1.3 7.5 3.4 1.4 7.5 3.4 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2457 PF10446.9 KER23734.1 - 1.6 7.8 15.4 2.2 7.3 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 KER23734.1 - 2.3 7.9 14.0 2.8 7.6 14.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 KER23734.1 - 4 7.5 6.1 5 7.1 6.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 KER23734.1 - 4.5 7.6 8.2 7.9 6.8 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KER23734.1 - 4.8 5.4 4.8 5.2 5.2 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KER23734.1 - 5.3 6.3 16.4 0.82 8.9 12.9 1.4 2 0 0 2 2 2 0 NOA36 protein GCIP PF13324.6 KER23734.1 - 5.5 6.5 6.1 5.9 6.4 6.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KER23734.1 - 9.4 4.2 11.8 11 4.0 11.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M14 PF00246.24 KER23736.1 - 4.7e-87 292.5 0.0 1.4e-71 241.7 0.0 3.2 3 0 0 3 3 3 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KER23736.1 - 1.1e-12 48.0 0.0 3.1e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KER23736.1 - 0.00027 20.9 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 CarboxypepD_reg-like domain AstE_AspA PF04952.14 KER23736.1 - 0.00056 19.1 0.1 0.0012 18.0 0.1 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Lactamase_B_6 PF16661.5 KER23738.1 - 1.7e-09 37.4 0.0 7e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KER23738.1 - 0.00089 18.5 0.0 0.0042 16.3 0.0 1.9 2 0 0 2 2 2 1 Putative beta-lactamase-like family Acyltransf_C PF16076.5 KER23738.1 - 0.042 13.9 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 Acyltransferase C-terminus EF-hand_12 PF17901.1 KER23738.1 - 0.18 12.2 0.0 0.51 10.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand fold domain BSD PF03909.17 KER23740.1 - 7.5e-13 48.3 0.3 1.7e-12 47.1 0.3 1.5 1 0 0 1 1 1 1 BSD domain TetR_C_32 PF09209.11 KER23742.1 - 0.056 13.4 0.0 8.9 6.3 0.0 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain COLFI PF01410.18 KER23747.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Antimicrobial_3 PF08025.11 KER23749.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Spider antimicrobial peptide fn3 PF00041.21 KER23754.1 - 2.4e-05 24.6 0.6 0.00094 19.5 0.1 2.7 2 0 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.21 KER23756.1 - 6.2e-11 42.5 6.4 0.19 12.1 0.2 4.2 4 0 0 4 4 4 4 Fibronectin type III domain F5_F8_type_C PF00754.25 KER23756.1 - 0.073 13.2 0.2 0.77 9.9 0.0 2.7 4 0 0 4 4 4 0 F5/8 type C domain fn3 PF00041.21 KER23757.1 - 5.6e-24 84.3 27.6 5.2e-05 23.5 0.7 6.1 6 0 0 6 6 6 6 Fibronectin type III domain Glyco_hydro_42C PF08533.10 KER23757.1 - 3.6e-11 42.6 0.4 0.095 12.4 0.0 4.3 3 0 0 3 3 3 3 Beta-galactosidase C-terminal domain DUF4959 PF16323.5 KER23757.1 - 1e-06 29.0 0.2 0.16 12.3 0.0 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4959) IL17R_fnIII_D2 PF16578.5 KER23757.1 - 0.00024 21.6 14.2 5 7.7 0.6 6.7 6 2 0 6 6 6 2 Interleukin 17 receptor D DUF4913 PF16259.5 KER23757.1 - 0.0032 17.5 3.2 24 5.1 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4913) DcpS_C PF11969.8 KER23757.1 - 0.006 17.0 0.5 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding Aida_C2 PF14186.6 KER23757.1 - 0.012 15.2 0.9 56 3.3 0.0 4.2 4 0 0 4 4 4 0 Cytoskeletal adhesion FHA PF00498.26 KER23757.1 - 0.016 15.6 3.5 47 4.4 0.1 4.3 4 0 0 4 4 4 0 FHA domain Sec-ASP3 PF15432.6 KER23757.1 - 0.017 15.3 0.0 32 4.7 0.0 4.1 6 0 0 6 6 6 0 Accessory Sec secretory system ASP3 Rav1p_C PF12234.8 KER23757.1 - 0.021 13.3 2.5 13 4.0 0.1 3.1 3 0 0 3 3 3 0 RAVE protein 1 C terminal DUF5052 PF16475.5 KER23757.1 - 0.037 13.7 12.8 1.1 8.9 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF5052) PYC_OADA PF02436.18 KER23757.1 - 0.075 12.8 0.0 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Conserved carboxylase domain VP_N-CPKC PF11475.8 KER23757.1 - 0.083 12.8 0.0 1.2e+02 2.7 0.0 3.4 3 0 0 3 3 3 0 Virion protein N terminal domain Cyc-maltodext_C PF10438.9 KER23757.1 - 0.098 12.8 7.1 14 5.9 0.1 4.9 5 0 0 5 5 5 0 Cyclo-malto-dextrinase C-terminal domain AFOR_N PF02730.15 KER23757.1 - 0.15 11.9 0.0 45 3.8 0.0 3.3 4 1 0 4 4 4 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF2839 PF10999.8 KER23757.1 - 1.1 9.7 13.4 51 4.3 0.0 6.3 6 2 0 6 6 6 0 Protein of unknown function (DUF2839) YhzD PF14120.6 KER23757.1 - 2.5 8.3 8.5 68 3.7 0.1 3.9 4 0 0 4 4 4 0 YhzD-like protein DUF3331 PF11811.8 KER23757.1 - 3.7 7.5 16.9 22 5.0 0.1 6.0 5 1 2 7 7 7 0 Domain of unknown function (DUF3331) RT_RNaseH_2 PF17919.1 KER23759.1 - 6.7e-10 38.9 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Aminotran_5 PF00266.19 KER23759.1 - 3.2e-08 32.9 0.1 1.8e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-V RT_RNaseH PF17917.1 KER23759.1 - 7.5e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2567 PF10821.8 KER23759.1 - 0.064 13.3 0.4 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) TPT PF03151.16 KER23760.1 - 7.2e-24 84.6 14.7 8.6e-24 84.4 14.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KER23760.1 - 2.1e-09 37.0 20.1 2.6e-09 36.7 20.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KER23760.1 - 2.3e-07 31.1 29.5 0.00012 22.2 9.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2809 PF10990.8 KER23760.1 - 0.03 15.0 3.9 1.7 9.4 0.0 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2809) GF_recep_IV PF14843.6 KER23761.1 - 0.023 14.5 0.9 0.029 14.2 0.9 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV COG4 PF08318.12 KER23762.1 - 9.6e-74 248.4 1.4 1.6e-73 247.7 1.4 1.3 1 0 0 1 1 1 1 COG4 transport protein Sec10 PF07393.11 KER23762.1 - 1.1e-10 40.7 0.1 3.7e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec10 RVT_1 PF00078.27 KER23762.1 - 5.5e-08 32.6 0.2 0.00019 21.0 0.0 3.4 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RINT1_TIP1 PF04437.13 KER23762.1 - 0.0012 17.8 0.1 0.003 16.5 0.1 1.6 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DIL PF01843.19 KER23762.1 - 0.0049 17.1 0.1 0.0049 17.1 0.1 3.1 2 1 0 2 2 2 1 DIL domain Corazonin PF17308.2 KER23762.1 - 0.053 13.9 1.6 0.26 11.7 0.2 2.8 3 0 0 3 3 3 0 Pro-corazonin RT_RNaseH_2 PF17919.1 KER23763.1 - 3.1e-05 23.9 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TPR_1 PF00515.28 KER23765.1 - 3.5e-13 48.8 7.2 8e-05 22.3 0.3 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER23765.1 - 1.7e-12 46.5 8.6 3e-05 23.8 0.5 4.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER23765.1 - 3.7e-08 33.9 5.3 1.2e-06 29.0 1.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER23765.1 - 5.3e-08 32.5 4.9 0.0066 16.6 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER23765.1 - 5.8e-06 26.4 1.6 2e-05 24.6 1.6 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER23765.1 - 2e-05 25.0 7.3 0.046 14.5 1.3 4.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER23765.1 - 0.00037 20.7 1.1 0.00037 20.7 1.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER23765.1 - 0.00045 20.0 2.0 0.62 10.2 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER23765.1 - 0.00078 19.5 1.4 0.03 14.4 0.4 2.8 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF4919 PF16266.5 KER23765.1 - 0.0016 18.4 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4919) TPR_11 PF13414.6 KER23765.1 - 0.0045 16.6 0.5 0.0045 16.6 0.5 3.3 3 1 1 4 4 4 1 TPR repeat TPR_17 PF13431.6 KER23765.1 - 0.011 16.1 5.2 0.065 13.6 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KER23765.1 - 0.012 16.0 0.7 0.063 13.7 0.7 2.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Cnd1 PF12717.7 KER23765.1 - 0.014 15.5 0.0 1 9.3 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 KER23765.1 - 0.016 15.7 4.0 0.016 15.7 4.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER23765.1 - 0.016 15.8 11.0 0.021 15.4 0.7 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER23765.1 - 0.035 14.3 8.7 0.074 13.3 0.4 3.4 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KER23765.1 - 0.048 12.7 0.4 0.079 11.9 0.4 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) AAA_6 PF12774.7 KER23765.1 - 0.067 12.1 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region HEAT PF02985.22 KER23765.1 - 1 9.8 4.9 1.9 9.0 0.0 4.3 4 0 0 4 4 2 0 HEAT repeat FGAR-AT_linker PF18072.1 KER23766.1 - 2 9.0 6.6 1.7 9.2 0.1 4.2 4 0 0 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain Sel1 PF08238.12 KER23767.1 - 9.9e-05 22.9 0.1 0.00021 21.9 0.1 1.6 1 0 0 1 1 1 1 Sel1 repeat Alpha-amyl_C PF09071.10 KER23767.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase, C terminal DUF494 PF04361.13 KER23767.1 - 0.12 12.2 0.4 0.21 11.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF494) DUF1707 PF08044.11 KER23767.1 - 0.13 12.3 0.9 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) PAN_4 PF14295.6 KER23768.1 - 0.0014 18.5 0.2 0.0031 17.4 0.2 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KER23768.1 - 0.0023 17.9 4.2 0.0052 16.7 4.2 1.7 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 KER23768.1 - 0.14 12.4 5.0 0.075 13.3 1.5 2.3 2 0 0 2 2 2 0 MANEC domain Lig_chan PF00060.26 KER23769.1 - 5.3e-33 114.0 0.0 1e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.28 KER23769.1 - 3.1e-29 102.2 0.1 2.3e-28 99.4 0.1 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.9 KER23769.1 - 5e-26 91.1 0.0 6.8e-25 87.5 0.0 2.3 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KER23769.1 - 5.3e-21 75.1 0.0 1e-19 70.9 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 KER23769.1 - 0.014 15.3 2.0 0.019 15.0 0.4 2.0 2 0 0 2 2 2 0 Ion channel DUF5316 PF17247.2 KER23769.1 - 0.074 13.1 0.7 1 9.4 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Antifungal_pept PF11410.8 KER23769.1 - 1.6 8.7 4.6 0.94 9.4 0.6 2.3 2 0 0 2 2 2 0 Antifungal peptide DHDPS PF00701.22 KER23771.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Ank_2 PF12796.7 KER23772.1 - 2e-24 86.0 1.3 1.4e-10 41.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER23772.1 - 1.2e-22 80.0 0.1 3.6e-10 40.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KER23772.1 - 8.7e-15 54.4 2.6 0.0004 20.7 0.0 5.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KER23772.1 - 1.1e-14 53.1 1.0 0.0033 17.8 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat PDZ_6 PF17820.1 KER23772.1 - 3.8e-14 52.3 0.2 1.1e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Ank_5 PF13857.6 KER23772.1 - 4.4e-14 52.4 1.1 7.7e-07 29.3 0.1 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) PDZ PF00595.24 KER23772.1 - 6e-14 52.2 0.0 1.3e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 KER23772.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM PDZ_2 PF13180.6 KER23772.1 - 0.00032 20.9 0.0 0.00082 19.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Lig_chan PF00060.26 KER23773.1 - 5.2e-46 156.2 0.0 8.1e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER23773.1 - 1.5e-28 99.3 0.0 2.7e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 KER23773.1 - 4.6e-19 68.7 0.0 6.8e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 KER23773.1 - 1.5e-18 67.1 0.0 4.8e-18 65.4 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 KER23773.1 - 0.25 11.3 2.9 0.95 9.5 2.9 2.1 1 1 0 1 1 1 0 Ion channel Kinesin PF00225.23 KER23777.1 - 2.9e-86 289.4 0.0 5.1e-55 186.7 0.0 2.7 1 1 1 2 2 2 2 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 KER23777.1 - 2.8e-37 127.0 1.0 1.4e-36 124.8 0.0 2.6 3 0 0 3 3 3 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 KER23777.1 - 5.3e-18 65.4 0.0 1.5e-15 57.4 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding Peptidase_S10 PF00450.22 KER23778.1 - 1.4e-121 406.9 0.3 2e-121 406.3 0.3 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KER23779.1 - 2e-112 376.6 0.1 4.8e-111 372.1 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase PAP2 PF01569.21 KER23780.1 - 1.3e-15 57.3 7.1 5.8e-14 52.0 3.6 3.7 2 2 0 2 2 2 1 PAP2 superfamily 7tm_1 PF00001.21 KER23781.1 - 2.6e-28 99.1 21.5 2.1e-27 96.1 20.2 2.6 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) FAM70 PF14967.6 KER23781.1 - 1.1 8.7 5.5 0.32 10.4 0.5 2.4 2 0 0 2 2 2 0 FAM70 protein UPF0183 PF03676.14 KER23782.1 - 2.7e-114 382.5 0.0 3.1e-114 382.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) DUF678 PF05077.12 KER23782.1 - 0.086 13.0 0.1 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DOT1 PF08123.13 KER23783.1 - 2.6e-69 232.9 0.0 6.1e-69 231.7 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 DHC_N1 PF08385.12 KER23783.1 - 0.16 10.6 0.5 0.25 10.0 0.5 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Osmo_CC PF08946.10 KER23783.1 - 2.8 8.3 6.3 1.5 9.1 3.5 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil F-box-like PF12937.7 KER23784.1 - 2.7e-17 62.4 1.0 6.3e-17 61.2 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER23784.1 - 6.3e-11 41.9 0.6 6.3e-11 41.9 0.6 3.1 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KER23784.1 - 0.0077 16.6 9.5 2 9.0 0.1 5.9 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER23784.1 - 0.041 13.4 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat F-box_4 PF15966.5 KER23784.1 - 0.054 13.4 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box Thioredoxin PF00085.20 KER23785.1 - 4.3e-08 33.1 0.0 1.1e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Evr1_Alr PF04777.13 KER23786.1 - 1.7e-18 66.9 0.0 3.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Erv1 / Alr family DUF35_N PF12172.8 KER23786.1 - 2.5e-05 24.1 0.8 5.7e-05 22.9 0.8 1.6 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) SKG6 PF08693.10 KER23786.1 - 0.0018 17.6 3.5 0.0032 16.8 3.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ECSCR PF15820.5 KER23786.1 - 0.1 12.4 0.4 0.2 11.5 0.4 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4381 PF14316.6 KER23786.1 - 0.28 11.4 0.9 23 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Cadherin PF00028.17 KER23789.1 - 2.5e-66 220.2 0.7 8.9e-15 54.9 0.1 7.9 7 2 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 KER23789.1 - 1.7e-07 31.2 7.6 0.68 10.0 0.1 6.4 6 0 0 6 6 6 3 Cadherin-like Cadherin_4 PF17803.1 KER23789.1 - 0.00021 21.9 10.2 0.81 10.4 0.1 6.2 6 0 0 6 6 6 1 Bacterial cadherin-like domain Cadherin_2 PF08266.12 KER23789.1 - 0.00054 19.7 0.0 7.8 6.4 0.0 4.4 4 1 0 4 4 4 1 Cadherin-like RET_CLD1 PF17756.1 KER23789.1 - 0.0048 17.2 0.0 3.2 8.0 0.0 3.3 3 0 0 3 3 3 1 RET Cadherin like domain 1 Ish1 PF10281.9 KER23790.1 - 0.0013 19.0 0.0 3.1 8.2 0.0 2.7 2 0 0 2 2 2 2 Putative stress-responsive nuclear envelope protein Peptidase_C78 PF07910.13 KER23790.1 - 0.031 13.8 4.3 2.1 7.8 0.4 2.2 1 1 1 2 2 2 0 Peptidase family C78 NTF2 PF02136.20 KER23793.1 - 2.5e-21 76.5 0.4 4e-20 72.6 0.3 2.5 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LapA_dom PF06305.11 KER23794.1 - 0.002 17.9 2.7 0.0024 17.6 2.7 1.1 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Cadherin_C_2 PF16492.5 KER23794.1 - 0.0056 17.4 0.0 0.0056 17.4 0.0 1.1 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 KER23794.1 - 0.039 14.8 0.0 0.06 14.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KER23794.1 - 0.063 13.2 0.1 0.063 13.2 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family Cas9-BH PF16593.5 KER23794.1 - 0.13 12.0 2.5 0.24 11.2 2.5 1.4 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 LST1 PF05083.13 KER23794.1 - 1.2 9.5 2.9 0.49 10.7 1.0 1.4 1 1 1 2 2 2 0 LST-1 protein DUF2373 PF10180.9 KER23795.1 - 1.1e-22 79.6 2.3 1.2e-22 79.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Fer2 PF00111.27 KER23795.1 - 5.1e-10 39.2 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Josephin PF02099.17 KER23795.1 - 0.04 14.0 0.4 0.066 13.3 0.4 1.3 1 0 0 1 1 1 0 Josephin Fer4_22 PF17179.4 KER23795.1 - 0.22 12.4 1.7 1.4 9.9 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain POP1 PF06978.11 KER23795.1 - 0.64 10.0 11.6 1.3 9.0 11.6 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 zf-RING_2 PF13639.6 KER23796.1 - 8.3e-11 42.0 8.6 2.3e-10 40.6 8.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KER23796.1 - 1.9e-08 33.9 5.5 1.9e-08 33.9 5.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KER23796.1 - 1.1e-06 28.5 4.4 4.3e-06 26.7 4.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER23796.1 - 1.6e-06 27.8 8.0 3.8e-06 26.7 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER23796.1 - 4.4e-06 26.4 8.3 1e-05 25.3 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER23796.1 - 2.8e-05 24.3 4.8 2.8e-05 24.3 4.8 2.5 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KER23796.1 - 0.0017 18.3 5.6 0.0017 18.3 5.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.8 KER23796.1 - 0.013 15.6 2.9 0.049 13.8 2.9 2.0 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KER23796.1 - 0.07 13.0 4.9 0.18 11.7 4.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KER23796.1 - 0.3 11.0 9.2 0.13 12.1 5.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KER23796.1 - 0.31 10.7 5.0 0.88 9.2 5.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KER23796.1 - 2.9 8.1 7.7 8.4 6.6 7.7 1.8 1 0 0 1 1 1 0 RING-variant domain CENP-F_leu_zip PF10473.9 KER23798.1 - 1 9.4 35.8 0.31 11.1 13.9 3.9 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Secretin PF00263.21 KER23798.1 - 1.9 8.1 7.6 0.39 10.3 2.9 2.2 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein GAS PF13851.6 KER23798.1 - 1.9 7.8 36.7 0.051 12.9 16.0 3.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 KER23798.1 - 2.5 8.6 0.0 2.5 8.6 0.0 5.2 5 2 1 6 6 6 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KER23798.1 - 7.7 6.6 13.8 2.8 8.0 1.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) G-alpha PF00503.20 KER23799.1 - 2.3e-90 303.3 0.3 2.7e-90 303.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER23799.1 - 1.2e-10 41.1 0.1 2.9e-10 39.9 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER23799.1 - 0.0059 16.0 0.1 0.0097 15.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SWIB PF02201.18 KER23800.1 - 8.9e-22 76.8 0.1 2.2e-21 75.5 0.0 1.6 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 KER23800.1 - 2.3e-06 27.4 0.2 4.4e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 DEK C terminal domain DUF4637 PF15470.6 KER23800.1 - 0.11 12.3 3.9 0.18 11.6 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) eIF-3c_N PF05470.12 KER23800.1 - 0.23 9.7 2.4 0.28 9.5 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Macoilin PF09726.9 KER23800.1 - 1.3 7.4 7.0 1.6 7.2 7.0 1.0 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 KER23800.1 - 1.5 8.5 9.3 2.3 7.9 9.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Apt1 PF10351.9 KER23800.1 - 1.5 7.6 9.3 1.9 7.2 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SET PF00856.28 KER23801.1 - 1.9e-18 67.4 0.1 7.7e-18 65.4 0.1 2.2 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.22 KER23801.1 - 6.2e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 KER23801.1 - 0.00024 21.2 3.4 0.0018 18.4 0.5 3.5 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N zf-CCHC PF00098.23 KER23801.1 - 0.04 14.0 0.9 0.17 12.0 0.9 2.2 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.6 KER23801.1 - 0.17 12.5 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Tmp39 PF10271.9 KER23804.1 - 2.9e-49 168.2 7.6 4.3e-49 167.7 7.6 1.3 1 0 0 1 1 1 1 Putative transmembrane protein UCH PF00443.29 KER23805.1 - 9.5e-26 90.8 0.0 2e-25 89.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER23805.1 - 0.01 15.5 0.1 0.38 10.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PAP_assoc PF03828.19 KER23807.1 - 2e-13 50.4 2.3 5.5e-12 45.7 0.5 2.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KER23807.1 - 3.8e-05 23.9 0.0 0.00015 22.0 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain zf-CCHC PF00098.23 KER23807.1 - 0.0026 17.8 2.2 0.0026 17.8 2.2 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 KER23807.1 - 0.013 15.3 0.4 0.013 15.3 0.4 3.5 4 0 0 4 4 4 0 Zinc knuckle Polbeta PF18765.1 KER23807.1 - 0.026 14.6 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-CCHC_2 PF13696.6 KER23807.1 - 0.43 10.5 16.2 0.078 12.8 1.1 3.3 3 0 0 3 3 3 0 Zinc knuckle PDZ PF00595.24 KER23808.1 - 1.2e-58 195.4 2.3 1.1e-15 57.7 0.1 4.6 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 KER23808.1 - 2.4e-40 136.1 29.8 3.7e-09 36.2 0.7 7.5 2 2 7 9 9 9 9 Leucine rich repeat PDZ_6 PF17820.1 KER23808.1 - 1.1e-31 108.4 7.0 1.1e-08 34.8 0.2 5.1 5 0 0 5 5 5 4 PDZ domain LRR_4 PF12799.7 KER23808.1 - 4.2e-27 93.7 39.0 0.00045 20.6 0.0 8.6 5 1 5 10 10 10 10 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 KER23808.1 - 6.1e-18 64.9 0.8 0.00035 20.9 0.0 4.5 4 0 0 4 4 4 4 PDZ domain LRR_9 PF14580.6 KER23808.1 - 8.8e-06 25.3 16.8 0.13 11.8 0.4 4.7 1 1 5 6 6 6 5 Leucine-rich repeat PDZ_4 PF17816.1 KER23808.1 - 0.014 15.8 0.0 32 5.0 0.0 3.8 4 0 0 4 4 4 0 PDZ domain LRR_5 PF13306.6 KER23808.1 - 0.087 12.8 0.7 6.2 6.8 0.0 3.3 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KER23808.1 - 7.2 7.6 41.9 6.9 7.6 0.1 11.7 12 2 0 12 12 12 0 Leucine Rich Repeat WW PF00397.26 KER23811.1 - 1.9e-07 31.1 0.0 4.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 WW domain Cytadhesin_P30 PF07271.11 KER23812.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Cytadhesin P30/P32 zf-C2H2_3rep PF18868.1 KER23814.1 - 0.17 12.5 4.3 0.39 11.4 2.8 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KER23815.1 - 2.8e-08 33.9 18.7 0.0078 17.0 2.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KER23815.1 - 7.8e-07 29.2 19.9 0.079 13.5 3.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KER23815.1 - 6.3e-05 23.2 14.1 0.18 12.1 1.4 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER23815.1 - 0.00026 21.3 12.7 0.0013 19.1 1.7 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KER23815.1 - 0.11 13.0 13.5 6.5 7.4 0.6 4.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 KER23815.1 - 1.4 9.3 10.0 39 4.7 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KER23815.1 - 7 6.7 10.8 0.64 10.0 0.5 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type bPH_3 PF14470.6 KER23819.1 - 0.024 15.0 0.1 0.046 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial PH domain DUF2457 PF10446.9 KER23821.1 - 0.77 8.8 4.6 1 8.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sulfotransfer_2 PF03567.14 KER23824.1 - 2e-39 136.0 0.1 2.7e-22 79.9 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 KER23824.1 - 4.5e-08 32.4 5.0 0.0029 16.5 0.8 3.0 2 1 0 3 3 3 2 Galactose-3-O-sulfotransferase Eco57I PF07669.11 KER23824.1 - 0.00051 20.5 0.0 2 9.0 0.0 2.4 2 0 0 2 2 2 2 Eco57I restriction-modification methylase Sulfotransfer_1 PF00685.27 KER23824.1 - 0.0076 15.8 1.6 2.3 7.6 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase domain ATS3 PF06232.11 KER23824.1 - 0.017 15.0 0.0 13 5.7 0.0 2.9 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) DUF2816 PF10992.8 KER23824.1 - 0.023 14.6 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) YwiC PF14256.6 KER23824.1 - 0.039 14.2 0.3 14 6.0 0.0 2.4 2 0 0 2 2 2 0 YwiC-like protein Adeno_E3_CR1 PF02440.15 KER23824.1 - 0.086 12.6 1.2 11 5.8 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Myotub-related PF06602.14 KER23825.1 - 0.0016 17.5 0.9 0.036 13.0 0.3 2.4 2 1 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KER23825.1 - 0.0061 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family RNA_pol_Rpb2_3 PF04565.16 KER23826.1 - 0.042 14.0 1.0 0.063 13.5 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 CAP PF00188.26 KER23827.1 - 1.3e-11 45.4 2.0 3.4e-05 24.7 0.0 3.6 3 0 0 3 3 3 3 Cysteine-rich secretory protein family zf-CCHC PF00098.23 KER23827.1 - 0.0009 19.2 1.9 0.0029 17.6 1.9 1.9 1 0 0 1 1 1 1 Zinc knuckle CENP-T_N PF16171.5 KER23827.1 - 0.019 13.9 0.1 0.032 13.1 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus RNase_H2-Ydr279 PF09468.10 KER23827.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain tRNA-synt_2b PF00587.25 KER23830.1 - 1e-08 35.4 0.0 2.8e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sybindin PF04099.12 KER23831.1 - 1.5e-32 112.5 0.0 1.7e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KER23831.1 - 2.4e-07 30.9 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-C2H2_4 PF13894.6 KER23833.1 - 9.4e-06 26.1 8.8 0.014 16.1 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KER23833.1 - 0.0003 21.1 6.8 0.0078 16.6 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KER23833.1 - 0.0039 17.0 1.7 0.0039 17.0 1.7 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KER23833.1 - 0.0083 15.9 7.1 0.42 10.4 0.6 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 KER23833.1 - 0.012 15.6 8.0 0.17 11.9 1.3 2.5 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KER23833.1 - 0.015 15.7 5.7 2.4 8.7 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger double domain RAG1_imp_bd PF12560.8 KER23833.1 - 0.02 14.4 0.8 0.035 13.6 0.8 1.3 1 0 0 1 1 1 0 RAG1 importin binding zf-C2H2_3rep PF18868.1 KER23833.1 - 0.027 15.1 2.2 1.6 9.4 0.2 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats ADK_lid PF05191.14 KER23833.1 - 0.08 12.9 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Lar_restr_allev PF14354.6 KER23833.1 - 0.16 12.3 1.5 0.34 11.3 1.5 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KER23833.1 - 0.42 10.8 5.1 2.7 8.2 3.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KER23833.1 - 2.9 8.3 9.0 6.9 7.1 1.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KER23833.1 - 7 6.3 9.0 0.33 10.6 0.8 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain zf-AN1 PF01428.16 KER23833.1 - 8.6 6.6 6.7 22 5.3 0.8 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger Ribosomal_L13 PF00572.18 KER23834.1 - 0.093 13.0 0.4 0.27 11.5 0.4 1.7 1 1 0 1 1 1 0 Ribosomal protein L13 RA PF00788.23 KER23836.1 - 7.6e-24 84.2 0.0 4.6e-13 49.6 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 KER23836.1 - 8.7e-14 51.7 0.1 5.2e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 KER23836.1 - 0.00045 20.5 0.2 0.0063 16.8 0.2 2.3 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER23836.1 - 0.0023 17.7 0.1 0.0082 16.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain AFG1_ATPase PF03969.16 KER23837.1 - 3.6e-52 177.5 0.0 5.5e-49 167.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Elf4 PF07011.11 KER23837.1 - 0.072 13.0 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain RNase_PH PF01138.21 KER23839.1 - 2.7e-10 40.8 0.0 7.3e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 rve PF00665.26 KER23840.1 - 4.2e-24 85.0 0.0 9.4e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 KER23840.1 - 1.2e-20 73.7 0.0 2.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER23840.1 - 3.6e-12 46.2 0.1 8.3e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KER23840.1 - 3.8e-05 23.7 0.2 0.00014 21.9 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER23840.1 - 0.043 13.6 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF4201 PF13870.6 KER23841.1 - 4.2e-24 85.2 26.1 4.2e-24 85.2 26.1 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) DUF2570 PF10828.8 KER23841.1 - 4.2 7.2 19.4 0.3 10.9 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2570) zf-C2H2 PF00096.26 KER23844.1 - 1.1e-22 79.1 36.2 1.6e-05 25.1 2.3 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER23844.1 - 1.5e-15 56.5 40.1 0.0022 18.7 2.4 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER23844.1 - 1.2e-12 47.7 34.1 0.00042 20.6 2.0 6.7 6 1 0 6 6 6 4 Zinc-finger double domain zf-Di19 PF05605.12 KER23844.1 - 1.3e-07 31.8 20.2 0.00098 19.4 2.6 3.9 2 2 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KER23844.1 - 1.8e-06 27.7 28.2 0.0061 16.4 2.6 5.5 5 1 0 5 5 5 3 zinc-finger of a C2HC-type ADK_lid PF05191.14 KER23844.1 - 8.7e-05 22.4 5.4 0.12 12.4 0.1 3.9 3 2 0 3 3 3 1 Adenylate kinase, active site lid Rad50_zn_hook PF04423.14 KER23844.1 - 0.00021 21.1 3.8 1.5 8.7 0.1 3.5 3 0 0 3 3 3 1 Rad50 zinc hook motif zf_UBZ PF18439.1 KER23844.1 - 0.00026 20.5 18.0 0.71 9.5 1.8 5.3 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger DUF1610 PF07754.11 KER23844.1 - 0.00026 20.9 11.5 0.074 13.0 0.2 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.10 KER23844.1 - 0.00033 20.7 19.6 0.00085 19.4 0.6 3.9 4 0 0 4 4 3 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KER23844.1 - 0.0019 17.9 0.6 0.0019 17.9 0.6 5.7 6 0 0 6 6 5 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KER23844.1 - 0.0022 18.7 15.9 3 8.5 1.4 4.5 1 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KER23844.1 - 0.0059 16.9 18.3 0.11 12.8 1.5 4.3 1 1 3 4 4 4 1 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KER23844.1 - 0.0063 17.2 11.0 0.3 11.9 0.2 3.2 2 1 1 3 3 3 1 zinc-ribbon family zf-met PF12874.7 KER23844.1 - 0.0097 16.3 22.0 1.6 9.2 0.1 5.8 6 0 0 6 6 5 1 Zinc-finger of C2H2 type OrfB_Zn_ribbon PF07282.11 KER23844.1 - 0.019 14.9 10.7 4.9 7.1 0.1 4.2 3 1 1 4 4 4 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 KER23844.1 - 0.023 14.4 14.7 2 8.3 0.4 4.5 4 0 0 4 4 4 0 zinc-ribbon domain DUF629 PF04780.12 KER23844.1 - 0.025 13.1 0.3 0.025 13.1 0.3 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 KER23844.1 - 0.045 14.1 17.5 0.93 9.9 0.3 5.5 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GATA PF00320.27 KER23844.1 - 0.063 12.9 6.0 0.5 10.0 1.1 3.1 2 1 0 2 2 2 0 GATA zinc finger DZR PF12773.7 KER23844.1 - 0.1 12.6 17.0 0.089 12.8 6.2 3.5 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KER23844.1 - 0.11 12.1 18.5 13 5.4 0.0 5.6 5 1 1 6 6 6 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KER23844.1 - 0.16 11.4 16.9 0.17 11.4 0.1 4.8 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KER23844.1 - 0.17 11.8 15.4 14 5.6 0.2 5.0 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) ARS2 PF04959.13 KER23844.1 - 0.31 11.4 6.3 3.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Arsenite-resistance protein 2 Ogr_Delta PF04606.12 KER23844.1 - 0.33 11.0 9.8 7.6 6.6 0.2 3.9 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger CpXC PF14353.6 KER23844.1 - 0.34 10.9 14.2 3.6 7.7 1.1 4.2 1 1 3 4 4 4 0 CpXC protein zf-RING_7 PF02591.15 KER23844.1 - 0.42 10.8 7.8 12 6.2 0.1 3.9 4 0 0 4 4 3 0 C4-type zinc ribbon domain DUF35_N PF12172.8 KER23844.1 - 0.55 10.2 15.3 4.8 7.2 0.4 4.3 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cys_rich_CPXG PF14255.6 KER23844.1 - 0.56 10.2 7.2 9.3 6.2 0.1 3.8 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-LITAF-like PF10601.9 KER23844.1 - 0.57 10.5 17.9 1.6 9.1 0.6 4.8 5 0 0 5 5 4 0 LITAF-like zinc ribbon domain TFIIS_C PF01096.18 KER23844.1 - 0.64 9.9 14.5 2.4 8.1 2.6 4.2 4 1 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-C2H2_6 PF13912.6 KER23844.1 - 0.66 10.0 29.6 1.1 9.4 0.7 5.8 5 1 0 5 5 5 0 C2H2-type zinc finger Rpr2 PF04032.16 KER23844.1 - 0.68 10.3 13.8 0.32 11.3 0.2 3.8 1 1 2 3 3 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.15 KER23844.1 - 0.81 9.8 27.3 0.45 10.6 1.1 4.5 3 1 1 4 4 4 0 BED zinc finger Ribosomal_L37ae PF01780.19 KER23844.1 - 1.1 9.4 10.3 5.2 7.2 2.1 4.0 2 1 1 3 3 3 0 Ribosomal L37ae protein family zinc_ribbon_4 PF13717.6 KER23844.1 - 1.3 9.0 15.2 31 4.6 0.3 5.2 5 0 0 5 5 5 0 zinc-ribbon domain DUF2752 PF10825.8 KER23844.1 - 1.8 8.7 4.3 95 3.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Nudix_N_2 PF14803.6 KER23844.1 - 1.9 8.4 15.0 11 6.0 0.1 4.1 3 1 0 3 3 3 0 Nudix N-terminal Sgf11 PF08209.11 KER23844.1 - 2.3 7.9 13.8 7.1 6.3 0.1 4.7 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) zf-Mss51 PF13824.6 KER23844.1 - 2.7 8.2 22.2 10 6.3 0.1 4.9 2 1 2 4 4 3 0 Zinc-finger of mitochondrial splicing suppressor 51 YhfH PF14149.6 KER23844.1 - 2.9 8.0 8.9 17 5.5 0.3 4.4 4 0 0 4 4 4 0 YhfH-like protein DNA_ligase_ZBD PF03119.16 KER23844.1 - 3.3 7.8 12.0 9.3 6.4 0.2 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2310 PF10071.9 KER23844.1 - 3.9 6.7 7.4 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zinc_ribbon_9 PF14369.6 KER23844.1 - 6 7.2 14.7 1.2 9.4 0.2 4.2 5 0 0 5 5 4 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 KER23844.1 - 6.1 6.9 26.1 0.17 11.8 0.7 5.1 4 2 0 5 5 5 0 SprT-like zinc ribbon domain Nop10p PF04135.12 KER23844.1 - 9.1 6.4 7.3 40 4.4 0.0 3.7 4 0 0 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family zf-MIZ PF02891.20 KER23845.1 - 6e-20 70.7 5.3 1.1e-19 69.9 5.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KER23845.1 - 0.00031 20.5 3.2 0.00078 19.2 3.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KER23845.1 - 1 9.7 5.7 2.2 8.7 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain 7tm_1 PF00001.21 KER23847.1 - 9.8e-50 169.3 0.0 1.7e-49 168.5 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER23847.1 - 8.3e-05 22.1 8.7 0.0023 17.4 2.4 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER23847.1 - 0.00055 19.7 1.0 0.00055 19.7 1.0 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER23847.1 - 0.14 11.9 5.8 1.3 8.7 3.5 2.8 2 1 0 2 2 2 0 Olfactory receptor LysM PF01476.20 KER23848.1 - 4.2e-06 26.7 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain PDEase_I PF00233.19 KER23850.1 - 8.7e-85 284.2 8.1 8.7e-85 284.2 8.1 1.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 KER23851.1 - 1.9e-24 85.3 0.1 1.9e-24 85.3 0.1 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal Cob_adeno_trans PF01923.18 KER23854.1 - 1.4e-52 178.2 0.0 1.9e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase IATP PF04568.12 KER23854.1 - 1.3e-07 31.9 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Antimicrobial11 PF08106.11 KER23854.1 - 5 7.3 7.6 0.21 11.6 1.6 1.9 2 0 0 2 2 2 0 Formaecin family OATP PF03137.20 KER23856.1 - 2e-78 264.1 0.0 1.5e-77 261.2 0.0 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Spin-Ssty PF02513.17 KER23856.1 - 0.044 13.5 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Spin/Ssty Family Kazal_2 PF07648.15 KER23856.1 - 0.21 11.7 2.3 10 6.3 0.2 2.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain 2OG-FeII_Oxy_2 PF13532.6 KER23860.1 - 6.8e-21 75.3 0.0 2.2e-20 73.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhoLip_ATPase_C PF16212.5 KER23861.1 - 1.3e-48 165.9 25.6 1.3e-48 165.9 25.6 4.5 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KER23861.1 - 1.8e-31 107.6 10.7 1e-15 57.2 0.4 3.1 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KER23861.1 - 1.1e-21 77.1 0.2 5.9e-06 25.9 0.0 4.4 4 1 0 4 4 4 3 E1-E2 ATPase Hydrolase PF00702.26 KER23861.1 - 1.1e-12 48.7 1.9 1.5e-07 31.9 0.0 5.1 5 0 0 5 5 5 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER23861.1 - 2e-06 27.8 0.0 2.8e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) TubC_N PF18563.1 KER23861.1 - 7.9e-06 25.8 1.3 3 7.9 0.1 4.4 4 0 0 4 4 4 2 TubC N-terminal docking domain Pentapeptide PF00805.22 KER23861.1 - 0.042 13.5 2.4 20 5.0 0.0 3.7 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) Hydrolase_3 PF08282.12 KER23861.1 - 0.057 13.1 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1281 PF06924.11 KER23861.1 - 0.059 12.9 0.0 12 5.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1281) HAD PF12710.7 KER23861.1 - 0.19 12.1 0.1 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Asp4 PF16996.5 KER23861.1 - 7.8 6.4 10.5 12 5.8 0.2 4.0 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 Lung_7-TM_R PF06814.13 KER23862.1 - 4.4e-65 219.8 17.0 5.8e-65 219.4 17.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 KER23862.1 - 6.8e-05 22.4 9.2 6.8e-05 22.4 9.2 1.8 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain PPTA PF01239.22 KER23863.1 - 3.8e-05 23.3 7.9 0.0017 18.0 0.0 4.4 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat PAC4 PF16093.5 KER23864.1 - 0.0011 19.1 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 ASC PF00858.24 KER23865.1 - 1.9e-40 139.2 0.1 2.9e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Thymidylat_synt PF00303.19 KER23867.1 - 8.7e-102 339.8 0.0 1.3e-101 339.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase La PF05383.17 KER23868.1 - 0.0011 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 La domain DUF525 PF04379.14 KER23869.1 - 9.2e-23 80.3 0.1 1.6e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 ApaG domain YccV-like PF08755.11 KER23869.1 - 5.9e-08 33.1 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Pkinase_Tyr PF07714.17 KER23870.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER23870.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain fn3 PF00041.21 KER23871.1 - 1.9e-06 28.1 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain FXa_inhibition PF14670.6 KER23871.1 - 0.001 19.3 7.0 0.069 13.4 1.0 2.8 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 KER23871.1 - 0.0011 18.7 2.0 0.0011 18.7 2.0 2.7 2 1 1 3 3 3 1 Putative ephrin-receptor like cEGF PF12662.7 KER23871.1 - 0.0054 16.6 5.2 0.089 12.7 0.9 2.9 2 0 0 2 2 2 1 Complement Clr-like EGF-like hEGF PF12661.7 KER23871.1 - 1.6 9.5 9.6 2.5 8.9 0.5 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_3 PF12947.7 KER23871.1 - 2.8 8.2 6.2 19 5.5 0.3 2.7 2 0 0 2 2 2 0 EGF domain EGF PF00008.27 KER23871.1 - 2.9 8.3 7.1 14 6.1 0.4 3.1 3 0 0 3 3 3 0 EGF-like domain PBD PF00786.28 KER23873.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 P21-Rho-binding domain RVT_1 PF00078.27 KER23874.1 - 6.1e-08 32.4 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAG6 PF12057.8 KER23874.1 - 0.044 13.5 5.0 3 7.6 0.3 3.5 3 0 0 3 3 3 0 BCL2-associated athanogene 6 A_deaminase PF00962.22 KER23876.1 - 1.3e-11 44.4 3.2 1.3e-10 41.1 3.2 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase PSS PF03034.15 KER23877.1 - 3e-24 86.2 0.2 6e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 Phosphatidyl serine synthase PSS PF03034.15 KER23879.1 - 3.4e-25 89.3 0.2 5.2e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase OGFr_N PF04664.13 KER23879.1 - 0.14 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region PSS PF03034.15 KER23880.1 - 3.9e-73 246.6 7.1 6e-73 246.0 7.1 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase RT_RNaseH_2 PF17919.1 KER23880.1 - 6.8e-07 29.2 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER23880.1 - 6.5e-05 23.2 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CH PF00307.31 KER23882.1 - 3e-20 72.4 0.0 3.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER23882.1 - 2.8e-06 27.1 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 KER23882.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein YdjC PF04794.12 KER23884.1 - 1.5e-56 192.0 0.0 1.7e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein P53 PF00870.18 KER23885.1 - 3.3e-24 85.7 0.2 7.6e-24 84.6 0.2 1.6 1 0 0 1 1 1 1 P53 DNA-binding domain RabGAP-TBC PF00566.18 KER23886.1 - 1.4e-22 80.4 7.5 5.6e-11 42.5 1.2 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Gtr1_RagA PF04670.12 KER23889.1 - 1.7e-24 86.5 0.3 1.8e-24 86.4 0.3 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Gtr1_RagA PF04670.12 KER23890.1 - 1.9e-21 76.5 0.1 2.1e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KER23890.1 - 0.06 13.6 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DAGAT PF03982.13 KER23893.1 - 9e-47 159.4 0.8 4.9e-37 127.5 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol acyltransferase DAGAT PF03982.13 KER23894.1 - 3e-22 78.9 0.0 1.8e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase DAGAT PF03982.13 KER23895.1 - 5.9e-59 199.4 0.1 1.3e-53 181.9 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase JAB PF01398.21 KER23896.1 - 1.3e-13 50.9 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PLCC PF14466.6 KER23898.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein AAA PF00004.29 KER23899.1 - 8.8e-40 136.2 0.0 1.9e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER23899.1 - 2e-13 49.9 0.2 9.6e-13 47.7 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KER23899.1 - 5.6e-08 32.7 0.0 1.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KER23899.1 - 5.1e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KER23899.1 - 5.4e-05 23.6 0.1 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KER23899.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KER23899.1 - 0.00022 21.4 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KER23899.1 - 0.00066 19.7 0.0 0.0065 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KER23899.1 - 0.00083 18.7 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KER23899.1 - 0.0062 15.9 1.1 0.011 15.2 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KER23899.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KER23899.1 - 0.012 15.2 0.2 0.057 12.9 0.1 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 KER23899.1 - 0.018 15.1 0.0 0.28 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KER23899.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KER23899.1 - 0.035 14.4 0.2 0.11 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER23899.1 - 0.036 14.6 0.3 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KER23899.1 - 0.045 13.2 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KER23899.1 - 0.062 13.7 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4296 PF14129.6 KER23899.1 - 0.13 12.9 0.1 0.36 11.5 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4296) AAA_28 PF13521.6 KER23899.1 - 0.13 12.4 0.5 0.31 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KER23899.1 - 0.16 11.6 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KER23899.1 - 0.17 11.6 0.1 1.1 8.9 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain ATG16 PF08614.11 KER23902.1 - 0.0075 16.5 5.1 0.013 15.7 5.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RPAP1_N PF08621.10 KER23902.1 - 0.043 13.6 0.4 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal Snapin_Pallidin PF14712.6 KER23902.1 - 0.048 14.1 0.3 0.048 14.1 0.3 2.4 1 1 2 3 3 3 0 Snapin/Pallidin Golgin_A5 PF09787.9 KER23902.1 - 0.054 13.0 3.5 0.078 12.4 3.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2508 PF10704.9 KER23902.1 - 0.16 12.1 2.2 1.7 8.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) KIAA1430 PF13879.6 KER23902.1 - 0.21 12.4 4.9 0.4 11.5 4.4 1.8 1 1 0 1 1 1 0 KIAA1430 homologue CorA PF01544.18 KER23902.1 - 0.46 9.8 4.2 0.65 9.3 4.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mod_r PF07200.13 KER23902.1 - 1 9.5 7.5 5.4 7.1 7.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.8 KER23902.1 - 3.6 7.7 7.2 2.2 8.3 1.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KER23902.1 - 5.4 7.7 8.5 3.9 8.2 0.4 2.9 2 1 1 3 3 3 0 SlyX ZapB PF06005.12 KER23902.1 - 7.2 7.1 9.1 8e+02 0.6 9.1 2.3 1 1 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.12 KER23902.1 - 9.6 6.7 8.3 15 6.0 1.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Hist_deacetyl PF00850.19 KER23904.1 - 6.8e-65 219.5 0.0 9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Na_K-ATPase PF00287.18 KER23907.1 - 8e-49 166.3 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Pkinase PF00069.25 KER23908.1 - 1.6e-62 211.3 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23908.1 - 7.2e-28 97.6 0.0 9.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER23908.1 - 0.00012 21.5 0.5 0.00019 20.9 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER23908.1 - 0.00046 20.2 0.1 0.00089 19.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER23908.1 - 0.001 18.4 0.2 0.0022 17.4 0.2 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER23908.1 - 0.015 14.9 0.6 0.032 13.8 0.6 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KER23908.1 - 0.02 13.8 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Trimer_CC PF08954.11 KER23908.1 - 0.03 13.9 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Trimerisation motif zf-C2H2 PF00096.26 KER23911.1 - 6.7e-15 54.6 50.1 0.00024 21.4 3.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER23911.1 - 7e-12 45.2 44.5 3.6e-06 27.2 0.3 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER23911.1 - 2.1e-09 37.4 44.9 0.064 14.1 1.8 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER23911.1 - 3.4e-07 30.5 22.2 3.2e-05 24.2 6.9 3.9 1 1 1 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 KER23911.1 - 3.5e-05 24.3 18.3 2.6 8.7 0.0 6.0 4 2 2 6 6 6 4 FOXP coiled-coil domain zf-met PF12874.7 KER23911.1 - 0.11 13.0 18.3 1.1 9.7 0.5 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KER23913.1 - 8.7e-21 73.2 54.3 0.0095 16.4 0.7 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER23913.1 - 1.6e-17 63.1 52.7 1.4e-05 25.3 0.9 9.0 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER23913.1 - 5.3e-11 42.4 49.2 0.036 14.9 0.5 8.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KER23913.1 - 9.1e-07 29.2 10.6 0.016 15.3 0.0 4.2 3 1 1 4 4 4 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KER23913.1 - 2.1e-05 24.7 19.1 0.056 13.8 2.1 5.0 4 2 0 5 5 4 3 C2H2-type zinc ribbon GAGA PF09237.11 KER23913.1 - 0.00035 20.3 3.6 0.089 12.6 0.1 3.2 3 0 0 3 3 3 2 GAGA factor IBR PF01485.21 KER23913.1 - 0.0019 18.4 26.9 0.77 10.0 2.1 5.5 3 2 0 4 4 4 3 IBR domain, a half RING-finger domain zf_CopZ PF18423.1 KER23913.1 - 0.02 14.9 14.7 0.78 9.7 0.1 5.5 2 2 4 6 6 6 0 Zinc binding domain Ogr_Delta PF04606.12 KER23913.1 - 0.059 13.4 17.1 0.37 10.8 2.4 4.8 4 1 0 4 4 4 0 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 KER23913.1 - 0.15 12.5 13.9 1.5 9.3 0.2 4.5 4 1 1 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KER23913.1 - 0.17 11.9 0.1 0.17 11.9 0.1 5.1 5 0 0 5 5 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 KER23913.1 - 0.47 10.6 6.9 40 4.4 0.2 4.6 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 KER23913.1 - 3.4 8.1 17.0 3.2 8.2 0.3 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KER23913.1 - 8.2 7.1 26.7 1.2 9.8 0.1 6.0 5 2 1 6 6 6 0 FOXP coiled-coil domain CDC45 PF02724.14 KER23915.1 - 0.0018 16.7 14.9 0.0018 16.7 14.9 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 KER23915.1 - 0.0073 14.5 39.8 0.0091 14.2 39.8 1.0 1 0 0 1 1 1 1 DNA polymerase phi TFB6 PF17110.5 KER23915.1 - 0.011 15.5 6.9 0.016 15.0 6.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 KER23915.1 - 0.63 9.6 21.6 0.84 9.2 21.6 1.3 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 KER23915.1 - 0.78 8.4 8.9 0.97 8.1 8.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KER23915.1 - 0.81 7.8 28.3 0.92 7.6 28.3 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KER23915.1 - 6.1 6.1 21.7 7.8 5.8 21.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trep_dent_lipo PF09710.10 KER23916.1 - 0.054 12.4 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Band_7 PF01145.25 KER23917.1 - 4e-23 82.3 0.3 4e-23 82.3 0.3 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER23917.1 - 0.0031 17.2 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family FHA_2 PF17913.1 KER23917.1 - 0.17 12.2 0.2 0.41 10.9 0.2 1.6 1 1 0 1 1 1 0 FHA domain ubiquitin PF00240.23 KER23918.1 - 1.5e-05 24.6 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KER23918.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SspB PF04386.13 KER23918.1 - 0.18 11.7 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Stringent starvation protein B FYDLN_acid PF09538.10 KER23920.1 - 0.001 19.7 4.8 0.0021 18.7 4.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.11 KER23920.1 - 0.0042 17.1 3.1 0.011 15.7 3.1 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KER23920.1 - 0.058 13.8 13.2 0.12 12.8 13.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KER23920.1 - 0.11 12.2 0.7 0.23 11.1 0.7 1.5 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.11 KER23920.1 - 0.12 11.3 1.5 0.17 10.7 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 KER23920.1 - 0.4 8.7 8.5 0.63 8.1 8.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KER23920.1 - 1 9.1 13.5 1.7 8.3 13.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 KER23920.1 - 1 7.9 4.1 1.4 7.4 4.1 1.1 1 0 0 1 1 1 0 Utp14 protein GCIP PF13324.6 KER23920.1 - 1.2 8.7 3.1 2.2 7.8 3.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ac81 PF05820.11 KER23920.1 - 1.2 8.6 12.1 2.4 7.7 12.1 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 RRN3 PF05327.11 KER23920.1 - 2.7 6.4 3.9 3.9 5.9 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2207 PF09972.9 KER23920.1 - 2.8 6.6 10.7 4.3 6.0 10.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NOA36 PF06524.12 KER23920.1 - 4.3 6.6 16.5 8.6 5.6 16.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 KER23920.1 - 4.8 7.5 9.4 4.5 7.5 7.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 KER23920.1 - 7.6 5.5 18.1 11 5.0 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BK_channel_a PF03493.18 KER23922.1 - 1.9e-21 76.1 0.0 9.6e-21 73.8 0.0 2.2 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit RVT_1 PF00078.27 KER23923.1 - 5.8e-10 39.1 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 KER23924.1 - 4.3e-11 42.6 2.7 4.3e-11 42.6 2.7 1.7 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 KER23924.1 - 0.012 14.9 2.6 0.025 13.8 2.5 1.7 1 1 0 1 1 1 0 Ion transport protein PDZ PF00595.24 KER23928.1 - 2.8e-12 46.8 0.0 4.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER23928.1 - 1.8e-10 40.5 0.1 3.7e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER23928.1 - 4.2e-05 23.8 0.1 0.00012 22.3 0.1 1.8 2 0 0 2 2 2 1 PDZ domain Baculo_LEF-10 PF07206.11 KER23933.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) RGS-like PF09128.11 KER23934.1 - 3.3e-10 40.0 0.3 5.7e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RGS PF00615.19 KER23934.1 - 0.00024 21.3 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain C1_1 PF00130.22 KER23935.1 - 1.5e-08 34.4 3.7 2.3e-08 33.8 3.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KER23935.1 - 0.1 12.9 4.6 0.18 12.1 4.6 1.5 1 0 0 1 1 1 0 C1 domain DUF2475 PF10629.9 KER23938.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2475) Pkinase PF00069.25 KER23943.1 - 2.1e-66 224.0 0.0 2.4e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER23943.1 - 7.1e-25 87.8 0.0 9.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER23943.1 - 1.7e-05 24.3 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KER23943.1 - 0.006 16.5 0.2 0.051 13.5 0.0 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER23943.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 KER23943.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC1 family CD36 PF01130.21 KER23945.1 - 1.9e-119 399.2 1.5 2.5e-119 398.9 1.5 1.0 1 0 0 1 1 1 1 CD36 family Adeno_E3_CR2 PF02439.15 KER23945.1 - 0.055 13.2 3.2 0.21 11.4 3.2 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RE_AspBHI_N PF18062.1 KER23945.1 - 0.084 12.4 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal zf-C2H2 PF00096.26 KER23946.1 - 1.8e-07 31.3 11.1 0.0016 18.8 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER23946.1 - 0.00018 22.0 9.5 0.018 15.8 2.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER23946.1 - 0.0003 21.1 3.9 0.011 16.0 0.1 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KER23946.1 - 0.0005 20.4 3.1 0.55 10.7 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KER23946.1 - 0.0018 18.6 7.6 0.0066 16.8 0.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER23946.1 - 0.084 13.2 7.5 0.16 12.3 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KER23946.1 - 0.12 12.8 0.7 0.12 12.8 0.7 1.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KER23946.1 - 1.3 9.1 10.0 6.7 6.8 2.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pet127 PF08634.10 KER23947.1 - 0.079 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 zf-C2H2 PF00096.26 KER23950.1 - 3.5e-07 30.3 28.2 0.00014 22.1 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER23950.1 - 6.6e-06 26.5 23.7 0.0003 21.4 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER23950.1 - 0.00041 20.5 0.2 0.00041 20.5 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KER23950.1 - 0.0015 18.3 1.8 0.01 15.7 0.2 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 KER23950.1 - 0.0035 17.7 1.0 0.0035 17.7 1.0 3.1 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KER23950.1 - 0.014 15.7 11.9 0.14 12.5 4.2 2.6 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KER23950.1 - 0.017 15.6 3.6 0.017 15.6 3.6 4.2 4 0 0 4 4 4 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 KER23950.1 - 1.1 9.3 9.1 10 6.2 0.2 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain C1_2 PF03107.16 KER23950.1 - 1.6 9.1 10.4 3.9 7.9 1.2 4.0 5 0 0 5 5 4 0 C1 domain PHD PF00628.29 KER23950.1 - 2.1 8.3 10.0 2.3 8.2 7.0 2.4 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KER23950.1 - 2.9 7.9 12.2 1.3 8.9 3.1 3.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CRAL_TRIO PF00650.20 KER23951.1 - 2.9e-11 43.3 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Inhibitor_I36 PF03995.13 KER23953.1 - 0.075 13.0 0.1 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Neur_chan_LBD PF02931.23 KER23954.1 - 2.5e-06 27.1 0.4 2.2e-05 24.0 0.4 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER23954.1 - 0.00033 20.8 4.9 0.00033 20.8 4.9 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 KER23954.1 - 1.8 6.8 5.1 2.4 6.3 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Steroid_dh PF02544.16 KER23955.1 - 5.8e-29 101.0 5.6 9.7e-28 97.0 5.6 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KER23955.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family PEMT PF04191.13 KER23955.1 - 0.011 16.1 2.1 0.036 14.5 2.1 1.9 1 1 0 1 1 1 0 Phospholipid methyltransferase Radial_spoke_3 PF06098.11 KER23957.1 - 4.6e-72 242.7 10.4 3.7e-57 193.8 1.9 2.9 3 0 0 3 3 3 2 Radial spoke protein 3 Forkhead PF00250.18 KER23959.1 - 9.1e-34 115.6 0.4 2.1e-24 85.6 0.1 2.4 2 0 0 2 2 2 2 Forkhead domain Forkhead PF00250.18 KER23960.1 - 6.6e-38 128.8 0.0 1.2e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Comm PF15957.5 KER23962.1 - 0.022 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Commissureless DUF3139 PF11337.8 KER23962.1 - 0.094 13.4 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Joubert PF15392.6 KER23962.1 - 3.3 7.4 12.1 46 3.6 12.1 2.1 1 1 0 1 1 1 0 Joubert syndrome-associated UPF0193 PF05250.11 KER23963.1 - 2.6e-29 102.6 12.1 4e-29 102.0 12.1 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Ras PF00071.22 KER23965.1 - 2.4e-44 150.8 0.2 3.1e-44 150.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER23965.1 - 1.7e-26 92.8 0.0 2.7e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER23965.1 - 6.6e-13 48.5 0.0 9.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER23965.1 - 1.7e-06 27.6 0.0 3.3e-05 23.3 0.0 2.1 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER23965.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KER23965.1 - 0.099 12.4 0.0 0.36 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KER23968.1 - 9e-08 31.8 0.0 0.0025 17.6 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 KER23969.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M17 PF00883.21 KER23971.1 - 4e-96 322.0 0.0 1.5e-80 270.8 0.0 2.2 2 0 0 2 2 2 2 Cytosol aminopeptidase family, catalytic domain HMG_box PF00505.19 KER23971.1 - 9e-08 32.4 0.2 3.5e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box Peptidase_M17_N PF02789.17 KER23971.1 - 7.7e-05 22.5 0.0 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain HMG_box_2 PF09011.10 KER23971.1 - 0.00034 21.1 0.0 0.00086 19.9 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KER23971.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain VATC PF18716.1 KER23971.1 - 0.04 13.8 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Vms1-associating treble clef domain RVT_1 PF00078.27 KER23973.1 - 7.2e-05 22.4 0.0 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIS PF01380.22 KER23974.1 - 8.8e-60 200.3 0.0 1.1e-31 109.4 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KER23974.1 - 1.3e-16 61.0 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KER23974.1 - 4.4e-13 49.2 0.0 9.6e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KER23974.1 - 8.5e-05 21.6 0.1 0.00014 20.8 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KER23974.1 - 0.05 13.6 0.0 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 SIS domain DUF1059 PF06348.11 KER23974.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) DUF3894 PF13033.6 KER23974.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) DUF1122 PF06557.11 KER23975.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Motile_Sperm PF00635.26 KER23978.1 - 2.8e-20 72.2 0.3 8e-15 54.6 0.1 2.3 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 KER23978.1 - 0.027 14.7 0.9 0.051 13.8 0.2 1.9 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4249 PF14054.6 KER23978.1 - 0.11 12.1 0.1 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4249) SDA1 PF05285.12 KER23979.1 - 0.64 9.4 49.5 0.83 9.0 49.5 1.1 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 KER23979.1 - 0.64 9.2 2.3 0.76 8.9 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TRAPPC-Trs85 PF12739.7 KER23980.1 - 5.7e-105 351.6 0.0 1.1e-104 350.7 0.0 1.5 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KER23980.1 - 6.6e-07 27.1 0.0 1.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TGase_elicitor PF16683.5 KER23983.1 - 0.051 12.3 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase elicitor Ofd1_CTDD PF10637.9 KER23984.1 - 2.4e-23 82.8 0.0 2.1e-21 76.5 0.0 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KER23984.1 - 3.6e-19 69.2 0.0 4.4e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KER23984.1 - 4.1e-13 50.0 0.0 1.6e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 KER23984.1 - 0.17 11.2 2.0 1.6 8.0 1.7 2.1 2 0 0 2 2 2 0 NOA36 protein Peptidase_C13 PF01650.18 KER23988.1 - 2.6e-65 220.5 5.2 9.8e-61 205.5 1.2 2.1 1 1 1 2 2 2 2 Peptidase C13 family Csm4_C PF17953.1 KER23988.1 - 0.026 14.4 0.1 0.19 11.6 0.0 2.5 2 1 1 3 3 3 0 CRISPR Csm4 C-terminal domain Succ_CoA_lig PF13607.6 KER23988.1 - 0.091 12.6 0.0 0.58 10.0 0.0 2.3 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain Phage_TAC_5 PF08890.11 KER23988.1 - 0.095 12.7 1.8 9.8 6.2 0.1 2.5 2 1 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC Homeodomain PF00046.29 KER23989.1 - 2.5e-14 52.9 0.4 4.5e-14 52.0 0.4 1.4 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 KER23989.1 - 1.1e-05 25.6 0.7 2.5e-05 24.4 0.7 1.6 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KER23989.1 - 0.00037 20.3 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DDE_Tnp_IS1595 PF12762.7 KER23991.1 - 0.033 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain PDZ_5 PF17817.1 KER23993.1 - 7.2e-22 77.5 0.1 1.3e-20 73.4 0.1 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KER23993.1 - 1e-11 45.0 0.9 2.3e-11 43.9 0.9 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER23993.1 - 0.091 12.6 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 PDZ domain FAM176 PF14851.6 KER23995.1 - 0.16 11.6 2.5 0.48 10.1 0.4 2.2 2 0 0 2 2 2 0 FAM176 family Spt5_N PF11942.8 KER23995.1 - 0.42 11.6 10.8 1.9 9.5 2.8 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.12 KER23995.1 - 2.2 7.5 11.4 0.033 13.5 1.6 2.2 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.6 KER23995.1 - 8.8 6.8 15.0 3.5 8.0 5.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 KER23995.1 - 9.8 6.2 10.2 0.11 12.6 1.0 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Fasciclin PF02469.22 KER23996.1 - 3.5e-37 127.5 0.0 4.1e-09 36.7 0.0 4.6 4 1 0 4 4 4 4 Fasciclin domain DUF3318 PF11780.8 KER23996.1 - 0.075 13.0 0.2 3.9 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) SDA1 PF05285.12 KER24003.1 - 0.0062 16.0 39.9 0.0071 15.8 39.9 1.1 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 KER24003.1 - 1.4 8.2 35.2 2 7.8 35.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 KER24003.1 - 9.5 5.1 5.8 13 4.7 5.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) 7tm_1 PF00001.21 KER24005.1 - 2e-10 40.5 0.2 2e-10 40.5 0.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER24005.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Tom5 PF10642.9 KER24005.1 - 0.086 12.9 0.2 3.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase 7tm_1 PF00001.21 KER24007.1 - 5.9e-32 111.0 1.2 5.9e-32 111.0 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER24007.1 - 0.00057 19.6 5.2 0.0009 18.9 5.2 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER24007.1 - 0.0016 18.2 0.5 0.0028 17.4 0.2 1.4 1 1 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 KER24007.1 - 0.0034 16.8 1.4 0.0038 16.6 1.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.9 KER24007.1 - 0.0065 16.0 2.3 0.013 15.0 2.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc DDE_Tnp_IS1595 PF12762.7 KER24009.1 - 2.4e-09 37.4 1.3 9e-07 29.0 0.2 3.3 3 0 0 3 3 3 3 ISXO2-like transposase domain ORC4_C PF14629.6 KER24010.1 - 1e-25 90.4 0.0 1.6e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KER24010.1 - 1.4e-06 28.8 0.1 4.7e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ets PF00178.22 KER24012.1 - 2.9e-37 127.0 0.4 4.9e-37 126.3 0.4 1.4 1 0 0 1 1 1 1 Ets-domain PAP2 PF01569.21 KER24013.1 - 1.9e-20 73.0 2.5 3.3e-20 72.2 2.5 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KER24013.1 - 0.00039 20.9 1.2 0.00039 20.9 1.2 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 KER24013.1 - 0.016 14.9 6.1 0.054 13.2 6.1 1.9 1 1 0 1 1 1 0 PAP2 superfamily RNase_T PF00929.24 KER24015.1 - 4.9e-05 23.9 0.0 0.00057 20.5 0.0 2.2 2 1 0 2 2 2 1 Exonuclease RNase_H_2 PF13482.6 KER24015.1 - 0.0031 17.5 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily bZIP_2 PF07716.15 KER24016.1 - 4.3e-09 36.3 12.3 6.7e-09 35.7 11.3 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KER24016.1 - 4.8e-05 23.4 12.2 0.00013 22.0 11.0 2.3 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KER24016.1 - 0.085 13.4 9.3 0.15 12.6 9.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF3450 PF11932.8 KER24016.1 - 0.21 10.9 6.3 0.28 10.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EMC3_TMCO1 PF01956.16 KER24016.1 - 3.9 7.2 5.0 5.9 6.6 5.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like WD40 PF00400.32 KER24017.1 - 0.044 14.7 31.8 0.61 11.1 1.5 10.1 10 2 0 10 10 10 0 WD domain, G-beta repeat 7tm_1 PF00001.21 KER24018.1 - 6e-80 268.4 0.0 7.4e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER24018.1 - 1.3e-13 50.9 6.7 2.3e-11 43.6 2.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER24018.1 - 4e-07 29.9 4.0 4e-07 29.9 4.0 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER24018.1 - 5.8e-07 29.5 8.6 7.7e-07 29.1 2.3 2.4 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srw PF10324.9 KER24018.1 - 3.6 6.8 9.8 17 4.6 4.4 2.6 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srw CSN8_PSD8_EIF3K PF10075.9 KER24020.1 - 2e-11 44.0 0.0 2.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family zf-C2H2 PF00096.26 KER24021.1 - 0.0014 19.0 2.4 16 6.2 0.1 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KER24021.1 - 0.0016 18.8 1.8 3.7 7.9 0.3 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KER24021.1 - 0.018 15.3 0.3 0.018 15.3 0.3 3.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KER24021.1 - 0.029 15.2 8.4 12 7.1 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Ogr_Delta PF04606.12 KER24021.1 - 0.097 12.7 2.6 0.6 10.1 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger 7tm_6 PF02949.20 KER24021.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor HLH PF00010.26 KER24022.1 - 4.5e-06 26.5 0.1 7.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KER24023.1 - 0.014 15.4 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain RVT_1 PF00078.27 KER24025.1 - 4.1e-20 72.3 0.0 7.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_6 PF13516.6 KER24025.1 - 7.8e-16 56.7 12.4 0.014 15.4 0.0 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 KER24025.1 - 9.4e-07 29.1 8.5 0.096 13.1 0.1 4.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER24025.1 - 0.0013 18.4 9.5 2 8.2 0.5 4.9 5 1 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 KER24025.1 - 0.0026 18.1 8.0 7.1 7.6 0.0 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat COMPASS-Shg1 PF05205.12 KER24026.1 - 1.1e-17 64.5 1.2 1.1e-17 64.5 1.2 2.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Ig_3 PF13927.6 KER24028.1 - 5.7e-69 228.7 0.8 1.8e-14 54.1 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KER24028.1 - 5.5e-63 209.1 0.0 3e-12 46.4 0.0 6.9 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER24028.1 - 1.8e-45 153.2 0.1 2.7e-09 37.2 0.0 6.2 5 1 1 6 6 6 5 Immunoglobulin domain ig PF00047.25 KER24028.1 - 1.3e-35 121.4 0.1 1.5e-07 31.5 0.1 6.3 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KER24028.1 - 1e-23 83.6 4.6 4.3e-05 23.6 0.0 8.9 6 5 0 6 6 6 5 Immunoglobulin V-set domain fn3 PF00041.21 KER24028.1 - 3.7e-18 65.7 0.7 7.2e-10 39.1 0.1 3.6 3 1 0 3 3 3 2 Fibronectin type III domain Ig_6 PF18452.1 KER24028.1 - 5e-14 51.6 0.0 0.14 11.7 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain C2-set_2 PF08205.12 KER24028.1 - 2.9e-09 36.9 0.8 0.6 10.2 0.0 5.4 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KER24028.1 - 9.2e-08 32.4 0.0 0.014 15.8 0.0 4.7 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain BiPBP_C PF06832.12 KER24028.1 - 0.0045 17.0 0.3 14 5.8 0.0 4.1 5 0 0 5 5 5 0 Penicillin-Binding Protein C-terminus Family zf-RRN7 PF11781.8 KER24028.1 - 0.0085 15.8 1.3 0.4 10.4 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Adeno_E3_CR1 PF02440.15 KER24028.1 - 0.014 15.2 0.0 11 5.8 0.1 3.5 4 0 0 4 4 4 0 Adenovirus E3 region protein CR1 Ig_C17orf99 PF17736.1 KER24028.1 - 0.026 14.5 0.0 5.6 7.1 0.0 4.2 5 0 0 5 5 5 0 C17orf99 Ig domain DUF2207 PF09972.9 KER24028.1 - 0.044 12.5 0.0 0.067 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L26 PF16906.5 KER24031.1 - 1.4e-37 128.0 4.9 2.2e-37 127.3 4.9 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KER24031.1 - 0.0003 20.6 1.9 0.00069 19.5 1.9 1.7 1 0 0 1 1 1 1 KOW motif SDA1 PF05285.12 KER24033.1 - 3.6e-79 266.7 30.7 3.6e-79 266.7 30.7 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KER24033.1 - 2.7e-11 43.6 0.0 9.2e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain Cnd1 PF12717.7 KER24033.1 - 0.00062 19.9 0.4 0.0018 18.3 0.4 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KER24033.1 - 0.014 15.0 1.1 0.021 14.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) IMD PF08397.11 KER24034.1 - 0.097 12.0 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 IRSp53/MIM homology domain XendoU PF09412.10 KER24036.1 - 5.2e-08 32.4 0.1 7.8e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease XendoU LisH_TPL PF17814.1 KER24036.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain Ets PF00178.22 KER24040.1 - 2.9e-24 85.3 2.5 8.7e-24 83.8 2.5 1.9 1 0 0 1 1 1 1 Ets-domain Ras PF00071.22 KER24041.1 - 2.5e-51 173.5 0.2 2.4e-50 170.3 0.2 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER24041.1 - 3.4e-27 95.1 0.1 9.4e-26 90.4 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER24041.1 - 2.1e-09 37.1 0.1 1.2e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER24041.1 - 0.00052 19.6 0.0 0.0046 16.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER24041.1 - 0.0079 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KER24041.1 - 0.093 12.3 0.0 8.3 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KER24041.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KER24042.1 - 2.6e-49 168.2 0.0 2.2e-48 165.2 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KER24042.1 - 0.00013 22.4 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 KER24042.1 - 0.00044 20.1 0.0 0.0027 17.5 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KER24042.1 - 0.00045 20.4 0.2 0.0026 17.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain NACHT PF05729.12 KER24042.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KER24042.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KER24042.1 - 0.0033 17.1 0.1 0.012 15.3 0.0 1.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 KER24042.1 - 0.0039 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MobB PF03205.14 KER24042.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KER24042.1 - 0.016 14.2 0.0 0.065 12.2 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KER24042.1 - 0.02 15.0 0.0 0.36 10.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KER24042.1 - 0.023 15.3 0.0 0.06 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KER24042.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.5 1 1 0 1 1 1 0 NTPase T2SSE PF00437.20 KER24042.1 - 0.038 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KER24042.1 - 0.047 13.0 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family CbiA PF01656.23 KER24042.1 - 0.047 13.7 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 KER24042.1 - 0.051 13.1 0.1 0.96 9.0 0.0 2.8 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 KER24042.1 - 0.053 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain KTI12 PF08433.10 KER24042.1 - 0.054 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.14 KER24042.1 - 0.056 12.7 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.19 KER24042.1 - 0.074 12.6 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KER24042.1 - 0.079 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KER24042.1 - 0.08 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KER24042.1 - 0.084 13.1 0.1 0.61 10.3 0.0 2.1 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KER24042.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KER24042.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KER24042.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KER24042.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KER24042.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KER24042.1 - 0.16 11.1 0.3 0.96 8.5 0.0 2.2 3 0 0 3 3 3 0 G-protein alpha subunit TsaE PF02367.17 KER24042.1 - 0.16 12.0 0.0 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-RING_2 PF13639.6 KER24043.1 - 4.1e-06 27.0 9.1 4.1e-06 27.0 9.1 2.3 2 0 0 2 2 2 1 Ring finger domain Exo_endo_phos_2 PF14529.6 KER24043.1 - 1.8e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KER24043.1 - 7.6e-05 22.3 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-ANAPC11 PF12861.7 KER24043.1 - 0.00028 20.9 3.0 0.0007 19.6 3.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KER24043.1 - 0.0011 18.9 8.0 0.0011 18.9 8.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KER24043.1 - 0.0012 19.1 7.2 0.0012 19.1 7.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KER24043.1 - 0.0013 18.5 5.0 0.0013 18.5 5.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KER24043.1 - 0.017 15.0 8.8 0.017 15.0 8.8 2.1 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.23 KER24043.1 - 0.099 12.1 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PepSY_TM PF03929.16 KER24043.1 - 0.45 10.1 2.7 2.6 7.6 1.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM region zf-RING_UBOX PF13445.6 KER24043.1 - 0.6 10.2 5.0 4.6 7.3 4.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger EMC3_TMCO1 PF01956.16 KER24043.1 - 1.3 8.7 5.4 2.8 7.6 5.4 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DZR PF12773.7 KER24043.1 - 2.3 8.3 10.0 0.35 10.9 1.7 2.8 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.8 KER24043.1 - 6.6 7.0 8.9 1.2e+02 3.0 8.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain HMG_box PF00505.19 KER24044.1 - 1.9e-13 50.6 0.8 2.9e-13 50.0 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER24044.1 - 0.00074 20.1 0.1 0.0013 19.3 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Actin PF00022.19 KER24047.1 - 3.7e-122 407.9 0.0 1.5e-121 405.8 0.0 1.7 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KER24047.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family Ank_2 PF12796.7 KER24049.1 - 4.5e-67 222.7 16.5 1.2e-14 54.7 0.2 7.3 3 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER24049.1 - 4.7e-67 221.6 29.8 6.9e-10 39.3 0.0 10.5 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER24049.1 - 1.6e-52 169.3 15.4 0.00066 19.9 0.1 13.0 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 KER24049.1 - 5.7e-47 157.2 16.8 9.7e-08 32.1 0.1 12.3 5 3 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KER24049.1 - 4.3e-45 150.2 17.3 0.00037 20.8 0.0 12.0 11 0 0 11 11 11 9 Ankyrin repeat Ion_trans PF00520.31 KER24049.1 - 9.1e-13 48.0 11.7 1.4e-12 47.3 11.7 1.2 1 0 0 1 1 1 1 Ion transport protein Sacchrp_dh_NADP PF03435.18 KER24049.1 - 0.12 12.6 3.0 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Tetraspanin PF00335.20 KER24049.1 - 5.7 6.6 8.2 0.26 11.0 1.7 2.0 3 0 0 3 3 3 0 Tetraspanin family DUF4542 PF15075.6 KER24051.1 - 1.5e-17 64.2 0.2 1.5e-17 64.2 0.2 2.7 2 2 0 2 2 2 1 Domain of unknown function (DUF4542) TerB_N PF13208.6 KER24051.1 - 0.018 14.7 0.6 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 TerB N-terminal domain Presenilin PF01080.17 KER24051.1 - 8.1 5.1 7.1 9 4.9 7.1 1.1 1 0 0 1 1 1 0 Presenilin VGCC_alpha2 PF08473.11 KER24052.1 - 1.5e-24 86.6 0.0 3.7e-23 82.0 0.0 2.7 1 1 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd dCache_1 PF02743.18 KER24052.1 - 8.6e-13 48.6 0.0 3.5e-11 43.4 0.0 2.4 2 1 0 2 2 2 1 Cache domain Cache_3-Cache_2 PF17201.4 KER24052.1 - 0.00058 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Cache 3/Cache 2 fusion domain CAAP1 PF15335.6 KER24052.1 - 0.046 14.3 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 VWA_N PF08399.11 KER24053.1 - 2e-11 44.4 0.0 3.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 VWA N-terminal VWA PF00092.28 KER24053.1 - 0.00014 22.2 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KER24053.1 - 0.00052 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KER24053.1 - 0.0085 16.0 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 KER24053.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain OB_NTP_bind PF07717.16 KER24056.1 - 0.14 12.6 0.1 24 5.4 0.2 2.4 1 1 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold UQ_con PF00179.26 KER24057.1 - 2.1e-26 92.3 0.1 2.9e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glycos_transf_2 PF00535.26 KER24058.1 - 3.8e-27 95.2 0.1 7.8e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KER24058.1 - 1.7e-10 41.2 0.0 1e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KER24058.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 OMPdecase PF00215.24 KER24059.1 - 9.7e-37 126.7 0.0 2e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 KER24059.1 - 1.2e-10 41.2 0.1 3.2e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Phage_GP20 PF06810.11 KER24059.1 - 0.3 10.9 2.5 0.54 10.0 2.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 APG6_N PF17675.1 KER24059.1 - 0.7 10.4 5.2 1.5 9.4 5.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 KER24059.1 - 2 7.2 8.4 3.3 6.5 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KER24059.1 - 3.2 8.4 6.2 2.9 8.6 4.3 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 KER24059.1 - 4.8 6.6 8.7 2.3 7.6 6.1 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 Dynactin PF12455.8 KER24061.1 - 4.1e-50 170.6 5.7 4.1e-50 170.6 5.7 5.8 4 3 1 6 6 6 1 Dynein associated protein HGTP_anticodon PF03129.20 KER24061.1 - 0.0087 16.2 7.9 1.1 9.5 0.1 4.0 4 0 0 4 4 4 2 Anticodon binding domain GP3_package PF16677.5 KER24061.1 - 0.27 11.4 3.2 0.79 9.9 0.1 2.8 2 0 0 2 2 2 0 DNA-packaging protein gp3 YabA PF06156.13 KER24061.1 - 7.2 7.3 0.0 4.5 8.0 0.5 10.0 5 2 4 9 9 9 0 Initiation control protein YabA CAP_GLY PF01302.25 KER24062.1 - 2.2e-25 88.4 1.6 3.4e-25 87.8 1.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain SET PF00856.28 KER24063.1 - 1.5e-26 93.8 0.4 1.9e-17 64.2 0.1 3.2 3 1 0 3 3 3 2 SET domain Tudor_4 PF18358.1 KER24063.1 - 3e-23 81.1 0.0 8e-23 79.8 0.0 1.8 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Pre-SET PF05033.16 KER24063.1 - 9.6e-17 61.6 6.5 9.6e-17 61.6 6.5 2.5 2 0 0 2 2 2 1 Pre-SET motif MBD PF01429.19 KER24063.1 - 4.2e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyl-CpG binding domain TUDOR_5 PF18359.1 KER24063.1 - 0.00031 20.4 0.1 0.00069 19.3 0.1 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 TUDOR_5 PF18359.1 KER24065.1 - 1.6e-10 40.5 0.2 6.8e-10 38.5 0.1 2.1 3 0 0 3 3 3 1 Histone methyltransferase Tudor domain 1 MIF4G_like_2 PF09090.11 KER24065.1 - 0.029 13.8 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 MIF4G like Prefoldin_2 PF01920.20 KER24065.1 - 0.033 14.1 0.4 0.08 12.9 0.4 1.6 1 0 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 KER24065.1 - 0.048 14.0 0.3 0.12 12.8 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1908 PF08926.11 KER24065.1 - 0.077 12.1 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DUF773 PF05600.12 KER24065.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 HALZ PF02183.18 KER24065.1 - 0.17 12.1 2.4 0.32 11.3 1.9 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper UDPGP PF01704.18 KER24066.1 - 3.7e-47 160.9 0.0 1.3e-44 152.5 0.0 2.0 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase T7SS_ESX_EspC PF10824.8 KER24066.1 - 0.084 13.4 0.1 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm NTP_transf_3 PF12804.7 KER24066.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain 7tm_1 PF00001.21 KER24067.1 - 4.1e-64 216.5 4.2 4.1e-64 216.5 4.2 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER24067.1 - 3.5e-06 26.6 11.6 3.5e-06 26.6 11.6 2.6 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER24067.1 - 5.8e-05 22.8 17.4 0.00015 21.5 17.4 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER24067.1 - 0.0011 18.8 8.4 0.0011 18.8 8.4 1.9 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.21 KER24069.1 - 4.4e-18 65.6 0.4 5.4e-18 65.3 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER24069.1 - 0.0059 16.0 0.4 0.0059 16.0 0.4 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KER24069.1 - 0.0098 15.2 0.6 0.0098 15.2 0.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Ctr PF04145.15 KER24069.1 - 0.04 14.5 0.6 0.9 10.2 0.6 2.2 1 1 0 1 1 1 0 Ctr copper transporter family LRR_8 PF13855.6 KER24070.1 - 8.1e-36 121.6 46.7 2.5e-10 40.0 2.4 5.2 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KER24070.1 - 3.5e-21 74.9 36.6 5.7e-05 23.4 0.7 6.9 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER24070.1 - 1.3e-08 34.2 29.4 14 6.7 0.1 11.0 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.6 KER24070.1 - 7.8e-05 22.2 16.5 0.0061 16.1 3.6 4.0 2 1 2 4 4 4 2 Leucine-rich repeat SOCS_box PF07525.16 KER24070.1 - 1.4 9.3 5.2 21 5.6 0.4 2.9 2 0 0 2 2 2 0 SOCS box LRR_8 PF13855.6 KER24071.1 - 7.5e-20 70.5 18.3 4.8e-08 32.6 1.0 4.1 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KER24071.1 - 1.6e-13 50.6 30.9 0.00038 20.8 3.2 5.5 2 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KER24071.1 - 0.096 12.8 0.2 0.096 12.8 0.2 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KER24071.1 - 0.1 13.2 22.1 0.12 13.0 0.3 6.5 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 KER24071.1 - 0.53 9.8 6.0 1.5 8.3 0.5 2.8 1 1 4 5 5 5 0 Leucine-rich repeat Hint PF01079.20 KER24073.1 - 3.6e-38 131.2 0.0 6.7e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Hint module HH_signal PF01085.18 KER24073.1 - 2e-19 69.8 0.1 1.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Hedgehog amino-terminal signalling domain Hint_2 PF13403.6 KER24073.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Hint domain Plant_NMP1 PF06694.11 KER24074.1 - 0.17 11.0 0.1 1.7 7.6 0.0 2.0 1 1 1 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) FANCD2OS PF15124.6 KER24076.1 - 0.31 11.2 3.4 1.7 8.8 2.2 2.3 2 0 0 2 2 2 0 FANCD2 opposite strand protein PLDc_2 PF13091.6 KER24078.1 - 1.8e-13 50.5 0.0 1.7e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KER24078.1 - 1.4e-07 31.4 0.0 0.021 15.0 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF4913 PF16259.5 KER24078.1 - 0.0069 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4913) 3HCDH_N PF02737.18 KER24079.1 - 1.3e-37 129.4 0.1 3.2e-37 128.2 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KER24079.1 - 8.6e-33 113.7 0.3 1.6e-32 112.8 0.3 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KER24079.1 - 1.6e-30 105.6 0.1 2.8e-22 79.2 0.0 6.0 6 0 0 6 6 6 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 KER24079.1 - 1.8e-20 73.7 0.1 3.1e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF903 PF06004.12 KER24079.1 - 0.00015 21.6 0.3 0.83 9.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF903) PsbR PF04725.12 KER24079.1 - 0.049 14.0 1.9 5.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR MORN PF02493.20 KER24079.1 - 0.19 11.7 5.7 6 7.0 0.1 2.9 3 0 0 3 3 3 0 MORN repeat XPG_I PF00867.18 KER24080.1 - 4e-32 110.4 0.0 7.9e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KER24080.1 - 6e-20 71.6 0.0 1.3e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KER24080.1 - 6.7e-07 29.8 0.0 2.8e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KER24080.1 - 0.005 17.4 0.4 0.2 12.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 KER24080.1 - 0.018 15.1 0.0 6.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF3560 PF12083.8 KER24080.1 - 0.051 13.7 0.1 8.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) XPG_I_2 PF12813.7 KER24080.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 XPG domain containing CDKN3 PF05706.12 KER24080.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) bZIP_1 PF00170.21 KER24082.1 - 2.7e-11 43.4 12.6 2.7e-11 43.4 12.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor Jun PF03957.13 KER24082.1 - 3.7e-08 33.6 2.3 8e-08 32.4 2.3 1.7 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_Maf PF03131.17 KER24082.1 - 3.8e-06 27.3 9.4 3.8e-06 27.3 9.4 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KER24082.1 - 6.9e-06 26.0 15.8 6.9e-06 26.0 15.8 2.2 3 0 0 3 3 3 1 Basic region leucine zipper Sipho_Gp157 PF05565.11 KER24082.1 - 0.0013 18.8 0.6 0.0026 17.8 0.6 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 ASD2 PF08687.11 KER24082.1 - 0.008 15.8 0.6 0.008 15.8 0.6 1.9 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 Prominin PF05478.11 KER24082.1 - 0.016 13.2 1.0 0.17 9.8 0.0 2.1 2 0 0 2 2 2 0 Prominin DUF3301 PF11743.8 KER24082.1 - 0.062 13.0 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) TSC22 PF01166.18 KER24082.1 - 0.44 10.9 1.8 2.1 8.7 0.4 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Transformer PF06495.11 KER24082.1 - 6 6.9 12.9 1.8 8.6 5.9 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein TBCC_N PF16752.5 KER24082.1 - 9.9 6.6 9.4 0.85 10.1 0.2 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Peptidase_M20 PF01546.28 KER24084.1 - 1.1e-24 87.3 0.0 1.4e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KER24085.1 - 9.7e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KER24085.1 - 1.5e-05 24.8 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Palm_thioest PF02089.15 KER24087.1 - 5.8e-87 291.5 0.0 6.7e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase BAAT_C PF08840.11 KER24087.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KER24087.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KER24087.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase EF-hand_6 PF13405.6 KER24088.1 - 0.0091 15.9 0.0 0.26 11.3 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain Sigma54_AID PF00309.20 KER24088.1 - 0.32 10.9 2.4 0.7 9.8 0.1 2.6 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Prenyltransf PF01255.19 KER24089.1 - 0.013 15.0 0.2 0.018 14.5 0.2 1.3 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RVT_1 PF00078.27 KER24090.1 - 1e-05 25.1 0.0 0.062 12.8 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DHHC PF01529.20 KER24092.1 - 2.7e-31 108.5 8.1 2.7e-31 108.5 8.1 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase S4 PF01479.25 KER24093.1 - 5.6e-08 32.4 0.5 1.5e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KER24093.1 - 8.2e-07 29.8 0.5 1.7e-06 28.9 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain MRP-S31 PF15433.6 KER24095.1 - 8.4e-39 134.1 5.2 3.4e-24 86.1 1.4 2.1 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S31 Plasmo_rep PF12135.8 KER24096.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Plasmodium repeat family Peptidase_C78 PF07910.13 KER24097.1 - 8.4e-19 67.9 0.0 5.6e-11 42.3 0.0 3.0 2 1 0 2 2 2 2 Peptidase family C78 DUF4350 PF14258.6 KER24097.1 - 0.34 11.4 2.6 18 5.9 0.2 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4350) Vps55 PF04133.14 KER24098.1 - 2.7e-27 95.0 10.8 3.1e-27 94.9 10.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ECF-ribofla_trS PF07155.12 KER24098.1 - 0.016 15.2 3.6 0.021 14.9 3.6 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DUF2838 PF10998.8 KER24098.1 - 0.017 15.4 4.4 0.022 15.0 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) CaMBD PF02888.16 KER24099.1 - 3.9e-31 107.1 4.4 1.1e-30 105.6 4.4 1.9 1 0 0 1 1 1 1 Calmodulin binding domain SK_channel PF03530.14 KER24099.1 - 4.5e-10 39.5 0.1 9.5e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 KER24099.1 - 4e-09 36.3 0.0 9.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 KER24101.1 - 7.9e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Usp PF00582.26 KER24104.1 - 4e-26 92.2 0.0 6.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Histone PF00125.24 KER24110.1 - 9.7e-13 48.6 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KER24110.1 - 2.3e-12 46.4 1.0 6.6e-12 45.0 1.0 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KER24110.1 - 1.5e-06 28.4 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone gag-asp_proteas PF13975.6 KER24112.1 - 2.4e-06 28.0 0.0 8.8e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER24112.1 - 7.8e-06 26.5 0.0 3.5e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 KER24112.1 - 4.5e-05 23.1 0.2 0.0001 21.9 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-met PF12874.7 KER24112.1 - 0.00039 20.7 29.8 0.22 11.9 0.3 7.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type RVP PF00077.20 KER24112.1 - 0.0013 19.0 0.2 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-ribbon_3 PF13248.6 KER24112.1 - 8 6.0 12.2 1.6 8.3 0.0 4.6 4 0 0 4 4 4 0 zinc-ribbon domain DcpS_C PF11969.8 KER24113.1 - 1e-24 87.2 0.5 1e-24 87.2 0.5 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KER24113.1 - 2.8e-16 59.7 3.6 6.6e-16 58.5 3.6 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KER24113.1 - 4.7e-14 52.9 0.4 8.4e-14 52.1 0.4 1.4 1 0 0 1 1 1 1 HIT domain zf-C2H2_6 PF13912.6 KER24113.1 - 0.04 13.9 2.3 0.04 13.9 2.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER24113.1 - 0.047 14.0 5.1 0.065 13.6 4.1 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KER24113.1 - 0.079 13.8 1.5 0.079 13.8 1.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KER24113.1 - 0.11 13.0 1.5 0.11 13.0 1.5 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Styelin PF17562.2 KER24113.1 - 0.13 12.7 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 Styelin Par3_HAL_N_term PF12053.8 KER24115.1 - 1.7e-23 82.7 1.0 8.2e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 N-terminal of Par3 and HAL proteins zf-C4H2 PF10146.9 KER24115.1 - 0.8 10.0 5.0 6 7.1 5.0 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein Pneumo_M2 PF07380.11 KER24116.1 - 0.086 13.1 0.1 0.099 12.9 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus M2 protein UPF0731 PF14982.6 KER24117.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 UPF0731 family PDZ PF00595.24 KER24118.1 - 2.4e-21 75.8 0.7 4e-11 43.1 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER24118.1 - 1.6e-15 56.7 3.3 3e-08 33.4 0.6 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER24118.1 - 3.2e-09 37.0 0.5 0.0001 22.5 0.1 2.8 3 0 0 3 3 3 2 PDZ domain Podoplanin PF05808.11 KER24118.1 - 1.3 9.1 6.3 0.15 12.2 0.7 2.3 2 0 0 2 2 2 0 Podoplanin Cadherin PF00028.17 KER24122.1 - 4.1e-11 43.2 0.0 2e-07 31.4 0.0 3.7 4 0 0 4 4 4 2 Cadherin domain SDA1 PF05285.12 KER24124.1 - 0.046 13.1 15.3 0.056 12.9 15.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KER24124.1 - 0.15 10.3 5.3 0.18 10.1 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER24124.1 - 0.39 8.9 15.8 0.51 8.5 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family EamA PF00892.20 KER24125.1 - 0.023 14.9 3.4 0.023 14.9 3.4 2.3 3 0 0 3 3 3 0 EamA-like transporter family BATS PF06968.13 KER24125.1 - 0.16 12.1 0.1 49 4.2 0.0 2.9 3 0 0 3 3 3 0 Biotin and Thiamin Synthesis associated domain G-patch PF01585.23 KER24128.1 - 6.1e-11 42.0 1.8 9.6e-11 41.4 0.1 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KER24128.1 - 0.0015 18.6 2.2 0.0041 17.2 1.5 2.1 2 1 0 2 2 2 1 G-patch domain Peptidase_M24 PF00557.24 KER24129.1 - 1.3e-48 165.5 0.0 1.7e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KER24129.1 - 5.8e-27 93.9 0.0 1.2e-26 92.9 0.0 1.5 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain OAD_beta PF03977.13 KER24131.1 - 0.0066 15.5 0.3 2.7 6.9 0.0 2.2 2 0 0 2 2 2 2 Na+-transporting oxaloacetate decarboxylase beta subunit Laminin_II PF06009.12 KER24131.1 - 0.014 15.4 0.0 0.014 15.4 0.0 4.3 5 0 0 5 5 5 0 Laminin Domain II DNA_topoisoIV PF00521.20 KER24131.1 - 0.072 12.0 2.7 0.13 11.1 2.7 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A AIP3 PF03915.13 KER24131.1 - 0.34 10.0 11.8 0.038 13.1 4.1 2.8 2 1 1 3 3 3 0 Actin interacting protein 3 CUB_2 PF02408.20 KER24132.1 - 0.0067 16.2 0.4 0.012 15.4 0.4 1.4 1 0 0 1 1 1 1 CUB-like domain Homeodomain PF00046.29 KER24135.1 - 1.2e-19 69.9 7.5 1.2e-19 69.9 7.5 2.3 2 0 0 2 2 2 1 Homeodomain Pkinase PF00069.25 KER24137.1 - 5.5e-59 199.7 0.0 5.3e-39 134.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER24137.1 - 2.4e-27 95.9 0.0 6.1e-23 81.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER24137.1 - 0.0003 20.2 0.3 0.015 14.6 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KER24137.1 - 0.0021 18.1 0.1 0.0058 16.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER24137.1 - 0.048 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER24137.1 - 0.052 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KER24137.1 - 0.059 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FAM76 PF16046.5 KER24138.1 - 0.016 14.6 14.1 0.021 14.2 14.1 1.1 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 KER24138.1 - 0.022 14.3 10.5 0.028 14.0 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit POR_N PF01855.19 KER24138.1 - 0.14 11.9 0.8 0.21 11.3 0.8 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PhoU PF01895.19 KER24138.1 - 0.14 12.6 7.4 0.076 13.5 2.2 2.4 2 1 0 2 2 2 0 PhoU domain THOC7 PF05615.13 KER24138.1 - 0.16 12.2 16.5 0.058 13.7 4.4 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Tropomyosin_1 PF12718.7 KER24138.1 - 0.19 11.8 25.2 0.48 10.6 6.4 2.9 1 1 1 3 3 3 0 Tropomyosin like DUF5082 PF16888.5 KER24138.1 - 0.26 11.6 12.0 0.42 10.9 7.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) RRF_GI PF12614.8 KER24138.1 - 0.3 11.2 5.5 0.24 11.6 3.7 1.8 1 1 1 2 2 2 0 Ribosome recycling factor HMMR_N PF15905.5 KER24138.1 - 0.38 10.2 22.9 1.1 8.7 20.8 1.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CDPS PF16715.5 KER24138.1 - 0.62 9.7 4.8 0.95 9.1 4.8 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase MPS2 PF17060.5 KER24138.1 - 1.3 8.3 12.4 1.1 8.5 10.8 1.6 1 1 1 2 2 2 0 Monopolar spindle protein 2 NPV_P10 PF05531.12 KER24138.1 - 1.4 9.5 9.2 37 4.9 9.2 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 KER24138.1 - 1.8 8.2 24.1 1.3 8.6 0.9 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HR1 PF02185.16 KER24138.1 - 1.9 8.7 21.0 0.29 11.3 5.6 3.8 2 1 2 4 4 4 0 Hr1 repeat SKA1 PF07160.12 KER24138.1 - 2.9 7.7 16.0 0.23 11.3 8.2 2.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Prismane PF03063.20 KER24138.1 - 2.9 6.5 5.6 3.7 6.1 5.6 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF16 PF01519.16 KER24138.1 - 5.1 7.6 13.5 26 5.4 13.4 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin PF02996.17 KER24138.1 - 5.5 6.9 15.7 0.17 11.8 3.9 3.5 1 1 2 3 3 3 0 Prefoldin subunit FtsX_ECD PF18075.1 KER24138.1 - 6.7 7.4 11.1 2.5 8.8 1.9 3.3 1 1 3 4 4 4 0 FtsX extracellular domain TMF_TATA_bd PF12325.8 KER24138.1 - 7.2 6.9 20.7 21 5.4 19.2 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KER24138.1 - 8.8 7.0 14.4 3.2 8.5 0.8 3.8 1 1 1 3 3 3 0 SlyX ThiF PF00899.21 KER24139.1 - 2.3e-64 217.1 0.0 3.9e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KER24139.1 - 1.2e-10 41.4 0.4 3.9e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 E2 binding domain Rhodanese PF00581.20 KER24139.1 - 5.5e-09 36.5 0.0 2e-07 31.5 0.0 2.6 1 1 0 1 1 1 1 Rhodanese-like domain AAA_22 PF13401.6 KER24139.1 - 0.014 15.7 0.1 0.16 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ribosomal_L2_C PF03947.18 KER24140.1 - 1.4e-15 57.6 0.0 4.2e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KER24140.1 - 7.1e-08 32.3 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MTS PF05175.14 KER24142.1 - 4.4e-11 42.6 0.1 6.4e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KER24142.1 - 2.5e-10 40.2 0.2 3.6e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KER24142.1 - 7.8e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KER24142.1 - 4.2e-06 27.4 0.1 9.7e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER24142.1 - 6.5e-05 22.8 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KER24142.1 - 0.0002 21.1 0.3 0.0011 18.7 0.3 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 KER24142.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Met_10 PF02475.16 KER24142.1 - 0.008 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KER24142.1 - 0.0084 16.0 0.2 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KER24142.1 - 0.0092 16.1 0.1 0.014 15.6 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KER24142.1 - 0.029 15.0 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KER24142.1 - 0.044 14.5 0.0 0.093 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KER24142.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DnaJ_C PF01556.18 KER24143.1 - 3e-27 95.5 0.0 4.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KER24143.1 - 7.8e-26 90.0 6.2 1.4e-25 89.2 6.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KER24143.1 - 3.5e-10 40.1 13.4 6.4e-10 39.2 13.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KER24143.1 - 0.032 14.2 15.2 0.36 10.8 1.1 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KER24143.1 - 1.3 9.1 7.6 0.43 10.6 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RVT_1 PF00078.27 KER24144.1 - 1e-38 133.1 0.0 1.8e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Reprolysin_2 PF13574.6 KER24144.1 - 1.5e-28 100.0 0.2 2.7e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KER24144.1 - 6.2e-21 75.4 0.0 1.4e-20 74.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KER24144.1 - 3.1e-14 53.6 0.3 8.1e-14 52.2 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KER24144.1 - 2.3e-09 37.2 0.0 4.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KER24144.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease AdoHcyase PF05221.17 KER24147.1 - 1.4e-103 346.1 0.0 5e-53 180.2 0.1 3.4 2 1 1 3 3 3 3 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KER24147.1 - 2.1e-67 226.2 7.6 7.9e-38 130.1 0.6 2.3 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KER24147.1 - 1.2e-05 24.8 1.0 0.022 14.1 0.2 2.4 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KER24147.1 - 0.00031 21.1 0.1 0.001 19.5 0.1 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KER24147.1 - 0.0021 17.4 0.4 0.086 12.2 0.1 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 KER24147.1 - 0.0032 16.8 0.2 0.0061 15.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KER24147.1 - 0.0038 17.3 0.1 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UPF0180 PF03698.13 KER24147.1 - 0.029 14.6 1.1 6 7.1 1.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) TrkA_N PF02254.18 KER24147.1 - 0.035 14.4 0.4 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.26 KER24147.1 - 0.037 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IlvN PF07991.12 KER24147.1 - 0.15 11.6 0.3 6 6.4 0.3 2.5 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TSP_1 PF00090.19 KER24148.1 - 4.7e-16 58.7 29.5 0.00099 19.3 7.4 5.1 4 1 0 4 4 4 4 Thrombospondin type 1 domain Ig_3 PF13927.6 KER24148.1 - 0.0003 21.3 0.0 0.001 19.6 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KER24148.1 - 0.0043 17.1 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain PolyA_pol PF01743.20 KER24149.1 - 2.8e-27 95.6 0.1 8.1e-25 87.7 0.2 2.3 2 0 0 2 2 2 2 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KER24149.1 - 7.5e-11 41.6 0.0 2.6e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A FERM_C PF09380.10 KER24150.1 - 3.2e-18 65.9 0.0 6.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KER24150.1 - 4.1e-11 42.7 0.0 8.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KER24150.1 - 1.1e-06 29.1 0.1 3.3e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 FERM central domain MIR PF02815.19 KER24152.1 - 0.016 15.1 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 MIR domain DUF3416 PF11896.8 KER24152.1 - 0.055 13.8 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Dynein_light PF01221.18 KER24154.1 - 8.9e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 SNURF PF07192.11 KER24154.1 - 0.036 13.9 1.2 0.13 12.2 1.2 1.9 1 0 0 1 1 1 0 SNURF/RPN4 protein Msap1 PF17077.5 KER24158.1 - 0.02 14.1 0.4 0.024 13.8 0.4 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 NCD3G PF07562.14 KER24158.1 - 0.088 12.8 0.7 0.088 12.8 0.7 2.7 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DZR PF12773.7 KER24158.1 - 5.2 7.2 10.6 0.42 10.7 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon EF-G-binding_N PF07299.11 KER24159.1 - 0.0075 16.8 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor G-binding protein, N-terminal Tropomyosin PF00261.20 KER24160.1 - 4.5e-43 147.3 45.7 5e-43 147.2 45.7 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 KER24160.1 - 1.5e-10 41.4 44.1 8.4e-10 39.0 14.6 2.9 1 1 1 2 2 2 1 Tropomyosin like DUF745 PF05335.13 KER24160.1 - 6e-05 22.8 28.2 0.02 14.6 10.6 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF745) Laminin_II PF06009.12 KER24160.1 - 0.00037 20.5 24.5 0.0071 16.4 10.0 3.4 1 1 2 3 3 3 1 Laminin Domain II HOOK PF05622.12 KER24160.1 - 0.003 15.8 34.6 0.06 11.5 18.4 2.7 1 1 1 2 2 2 2 HOOK protein DUF16 PF01519.16 KER24160.1 - 0.0035 17.8 23.3 0.89 10.1 4.0 3.5 1 1 3 4 4 4 2 Protein of unknown function DUF16 ATG16 PF08614.11 KER24160.1 - 0.0047 17.2 39.3 0.017 15.3 21.0 2.9 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 KER24160.1 - 0.0049 17.6 17.4 0.058 14.1 4.8 4.1 2 1 2 4 4 4 1 Occludin homology domain MscS_porin PF12795.7 KER24160.1 - 0.0059 16.2 29.0 0.08 12.5 10.6 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 KER24160.1 - 0.0067 16.6 22.0 0.4 10.8 5.9 3.1 1 1 2 3 3 3 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KER24160.1 - 0.01 15.9 20.6 0.036 14.1 6.2 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 KER24160.1 - 0.012 16.0 16.0 0.012 16.0 16.0 3.0 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) GvpH PF05455.11 KER24160.1 - 0.017 15.2 1.6 0.025 14.7 0.5 1.8 1 1 0 1 1 1 0 GvpH EzrA PF06160.12 KER24160.1 - 0.021 13.0 29.8 0.14 10.3 9.6 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Sugarporin_N PF11471.8 KER24160.1 - 0.039 13.9 8.1 0.039 13.9 8.1 4.1 3 1 1 4 4 4 0 Maltoporin periplasmic N-terminal extension DUF2087 PF09860.9 KER24160.1 - 0.041 14.0 1.6 0.097 12.8 0.5 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Filament PF00038.21 KER24160.1 - 0.042 13.4 34.1 0.16 11.6 20.4 2.9 1 1 1 2 2 2 0 Intermediate filament protein Mod_r PF07200.13 KER24160.1 - 0.096 12.8 29.2 0.54 10.4 9.2 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BST2 PF16716.5 KER24160.1 - 0.11 13.1 25.3 0.13 12.8 9.9 3.3 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 Golgin_A5 PF09787.9 KER24160.1 - 0.15 11.5 33.4 0.31 10.5 5.1 2.7 1 1 0 2 2 2 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 KER24160.1 - 0.19 12.3 27.8 1.1e+02 3.4 3.6 3.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.6 KER24160.1 - 0.21 12.0 39.5 2.2 8.7 5.6 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Laminin_I PF06008.14 KER24160.1 - 0.22 11.2 29.8 0.23 11.2 8.9 2.8 1 1 1 2 2 2 0 Laminin Domain I DUF3584 PF12128.8 KER24160.1 - 0.26 8.7 32.2 0.53 7.7 8.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 KER24160.1 - 0.28 11.5 37.0 0.82 10.1 16.2 3.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region XhlA PF10779.9 KER24160.1 - 0.38 11.0 26.7 0.42 10.8 0.8 5.1 2 2 2 5 5 5 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 KER24160.1 - 0.4 10.7 40.6 0.53 10.3 19.9 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 KER24160.1 - 0.4 11.0 26.9 0.22 11.8 7.1 4.1 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flagellin_N PF00669.20 KER24160.1 - 0.46 10.6 12.2 0.049 13.7 3.1 3.0 2 2 2 4 4 4 0 Bacterial flagellin N-terminal helical region DUF4763 PF15960.5 KER24160.1 - 0.5 9.6 17.4 0.093 12.0 2.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) CALCOCO1 PF07888.11 KER24160.1 - 0.6 8.9 37.8 0.055 12.3 29.8 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 KER24160.1 - 0.69 10.7 30.2 0.057 14.2 10.1 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Baculo_PEP_C PF04513.12 KER24160.1 - 0.69 9.9 11.4 4.3 7.4 3.6 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 KER24160.1 - 0.92 7.6 33.4 0.13 10.4 20.0 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil HemX PF04375.14 KER24160.1 - 1.2 8.4 22.3 2.5 7.3 2.0 2.7 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 KER24160.1 - 1.5 8.0 22.9 0.28 10.4 3.6 2.7 1 1 3 4 4 4 0 TMPIT-like protein AAA_13 PF13166.6 KER24160.1 - 1.5 7.4 30.7 0.76 8.3 26.2 2.3 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.12 KER24160.1 - 1.6 9.2 10.3 73 3.9 0.3 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TACC_C PF05010.14 KER24160.1 - 1.9 8.2 33.3 8.7 6.1 20.7 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HMMR_N PF15905.5 KER24160.1 - 2 7.8 35.1 4.4 6.7 19.9 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Vac_Fusion PF02346.16 KER24160.1 - 2.1 8.0 8.7 3.5 7.3 0.1 4.1 3 2 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 GAS PF13851.6 KER24160.1 - 2.6 7.4 35.7 0.28 10.5 2.7 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 KER24160.1 - 3.1 6.6 37.5 15 4.3 22.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Sec20 PF03908.13 KER24160.1 - 3.4 7.7 9.4 2.1 8.3 0.3 3.7 1 1 3 4 4 4 0 Sec20 CHDCT2 PF08074.11 KER24160.1 - 3.4 7.8 12.9 3 8.0 5.5 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SlyX PF04102.12 KER24160.1 - 3.4 8.3 26.1 3.1 8.5 3.4 5.4 1 1 4 5 5 5 0 SlyX Spc7 PF08317.11 KER24160.1 - 3.9 6.2 38.2 5.1 5.9 9.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein SKA1 PF07160.12 KER24160.1 - 4.3 7.1 21.1 8.1 6.2 6.6 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 HAUS-augmin3 PF14932.6 KER24160.1 - 4.4 6.8 31.8 7.1 6.1 16.5 2.8 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Paralemmin PF03285.15 KER24160.1 - 5 6.6 26.5 0.73 9.4 7.1 3.0 2 1 1 3 3 3 0 Paralemmin Tnp_22_trimer PF17489.2 KER24160.1 - 5.5 7.0 17.6 2 8.4 0.1 4.8 2 1 3 5 5 5 0 L1 transposable element trimerization domain RPW8 PF05659.11 KER24160.1 - 5.6 6.6 17.9 0.16 11.7 3.5 3.6 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NBP1 PF08537.10 KER24160.1 - 5.9 6.2 20.0 11 5.3 10.9 2.4 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 BRE1 PF08647.11 KER24160.1 - 6.4 6.9 33.7 0.59 10.2 3.3 3.6 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase BORCS7 PF16088.5 KER24160.1 - 6.9 7.0 11.0 0.56 10.5 1.9 3.2 1 1 2 4 4 3 0 BLOC-1-related complex sub-unit 7 KxDL PF10241.9 KER24160.1 - 7.1 7.0 22.1 2.9 8.3 1.3 4.1 2 2 3 5 5 5 0 Uncharacterized conserved protein COG2 PF06148.11 KER24160.1 - 7.3 6.7 25.6 2.3 8.3 2.5 4.1 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF724 PF05266.14 KER24160.1 - 9.7 6.0 32.8 48 3.7 11.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 KER24161.1 - 4e-91 304.6 78.5 2.7e-88 295.4 52.3 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KER24161.1 - 1.3e-37 129.1 65.5 2.1e-34 118.7 37.3 3.0 2 1 1 3 3 3 3 Tropomyosin like ERM PF00769.19 KER24161.1 - 0.0026 17.6 21.0 0.0026 17.6 21.0 3.0 1 1 2 3 3 3 1 Ezrin/radixin/moesin family Vps53_N PF04100.12 KER24161.1 - 0.0077 15.2 9.6 0.0077 15.2 9.6 2.6 1 1 2 3 3 3 2 Vps53-like, N-terminal MscS_porin PF12795.7 KER24161.1 - 0.014 15.0 51.2 0.017 14.7 30.0 2.4 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Flagellin_C PF00700.21 KER24161.1 - 0.034 14.5 11.6 0.039 14.3 2.5 3.9 3 1 1 4 4 4 0 Bacterial flagellin C-terminal helical region ALO PF04030.14 KER24161.1 - 0.035 13.9 0.7 0.058 13.2 0.7 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase CALCOCO1 PF07888.11 KER24161.1 - 0.036 12.9 51.6 0.051 12.5 51.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 KER24161.1 - 0.047 11.9 51.4 0.09 11.0 20.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 KER24161.1 - 0.14 12.1 32.7 0.52 10.3 4.5 3.9 1 1 3 4 4 4 0 Laminin Domain II Fez1 PF06818.15 KER24161.1 - 0.2 12.1 49.3 3.9 7.9 27.4 2.3 1 1 1 2 2 2 0 Fez1 ORF6C PF10552.9 KER24161.1 - 0.31 11.1 0.1 0.31 11.1 0.1 4.1 3 1 1 4 4 4 0 ORF6C domain DUF3142 PF11340.8 KER24161.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3142) SH3BP5 PF05276.14 KER24161.1 - 0.35 10.6 36.3 0.034 14.0 12.3 2.5 1 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) GAS PF13851.6 KER24161.1 - 0.41 10.0 48.0 2.6 7.3 24.8 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KER24161.1 - 0.41 10.7 31.3 0.66 10.0 1.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 KER24161.1 - 0.46 10.1 52.3 0.34 10.5 5.3 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 KER24161.1 - 0.7 9.9 16.0 0.62 10.1 4.3 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.6 KER24161.1 - 1.7 8.8 43.1 0.13 12.5 9.7 3.6 1 1 1 3 3 3 0 Up-regulated During Septation CC2-LZ PF16516.5 KER24161.1 - 2 8.8 41.9 0.094 13.1 5.0 4.8 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator AAA_13 PF13166.6 KER24161.1 - 2.1 6.9 43.8 1.7 7.2 23.7 2.2 1 1 0 2 2 2 0 AAA domain Golgin_A5 PF09787.9 KER24161.1 - 2.1 7.7 54.6 0.26 10.7 18.7 2.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 BORCS7 PF16088.5 KER24161.1 - 3 8.2 13.5 3.6 7.9 0.2 3.8 2 2 2 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF16 PF01519.16 KER24161.1 - 3.2 8.3 33.2 5.6 7.5 3.9 4.1 1 1 3 4 4 4 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KER24161.1 - 3.5 7.8 30.7 1.1 9.4 1.3 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.13 KER24161.1 - 4 5.7 55.2 0.071 11.5 23.1 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein EzrA PF06160.12 KER24161.1 - 4.3 5.4 44.7 0.29 9.2 5.4 3.6 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA DUF4472 PF14739.6 KER24161.1 - 4.7 8.0 49.1 0.6 10.9 12.1 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 KER24161.1 - 5 7.5 15.1 36 4.7 2.1 4.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KER24161.1 - 5.1 7.6 15.0 15 6.2 0.4 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 KER24161.1 - 5.1 7.9 18.7 0.27 11.9 7.9 3.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 KER24161.1 - 5.4 6.3 48.2 0.27 10.5 22.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KER24161.1 - 5.9 6.7 50.4 0.7 9.7 19.2 3.3 1 1 1 2 2 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 KER24161.1 - 6.2 6.9 49.5 0.28 11.3 8.0 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 KER24161.1 - 7.2 6.9 40.5 0.78 10.0 2.0 5.4 4 1 1 5 5 5 0 Haemolysin XhlA HemX PF04375.14 KER24161.1 - 8 5.6 44.0 1.3 8.2 6.4 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3573 PF12097.8 KER24161.1 - 8.8 5.0 6.2 13 4.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Bax1-I PF01027.20 KER24162.1 - 3.8e-40 137.9 28.8 4.4e-40 137.7 28.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 KER24162.1 - 4.1 5.6 17.5 5.1 5.3 17.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DoxX_3 PF13781.6 KER24162.1 - 7 7.4 10.4 1 10.0 1.9 2.5 2 1 1 3 3 3 0 DoxX-like family Ig_3 PF13927.6 KER24164.1 - 1.5e-35 121.7 13.6 3.6e-13 49.9 0.2 7.8 7 1 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 KER24164.1 - 8.8e-29 99.4 0.0 1.3e-06 28.4 0.0 8.8 8 2 0 8 8 8 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER24164.1 - 1.2e-23 83.3 9.6 7.5e-05 23.0 0.0 8.4 8 0 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 KER24164.1 - 5.3e-17 61.8 8.2 3.8e-06 27.0 0.0 7.6 7 1 0 7 7 7 3 Immunoglobulin domain V-set PF07686.17 KER24164.1 - 9.5e-11 41.8 8.3 1.9 8.7 0.1 8.6 7 2 0 7 7 7 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER24164.1 - 5.7e-09 35.9 1.6 0.0026 17.8 0.1 4.9 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KER24164.1 - 7.4e-05 23.1 0.1 1.1 9.8 0.0 5.3 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 KER24164.1 - 0.0062 16.3 0.8 0.25 11.1 0.0 3.6 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 V-set_CD47 PF08204.11 KER24164.1 - 0.039 13.9 0.1 34 4.4 0.0 3.8 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain Ig_4 PF16680.5 KER24164.1 - 0.04 14.2 0.3 46 4.4 0.0 5.2 7 0 0 7 7 7 0 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 KER24165.1 - 0.0062 16.8 1.1 0.99 9.8 0.0 3.1 3 0 0 3 3 3 2 Fibronectin type III domain RCS1 PF07326.11 KER24165.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 TRAM_LAG1_CLN8 PF03798.16 KER24166.1 - 5.9e-30 104.5 24.5 1.4e-29 103.3 24.5 1.6 1 0 0 1 1 1 1 TLC domain RhoGAP PF00620.27 KER24167.1 - 2.7e-38 131.2 0.0 4.9e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PDZ_6 PF17820.1 KER24167.1 - 7.7e-07 28.9 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER24167.1 - 7.4e-05 23.0 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER24167.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain HrpE PF06188.12 KER24167.1 - 0.26 11.1 1.7 0.48 10.3 1.7 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TNFR_c6 PF00020.18 KER24171.1 - 3e-25 88.3 48.8 1.5e-08 34.8 8.2 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TNFR_16_TM PF18422.1 KER24171.1 - 3.1e-16 59.0 1.3 7.4e-16 57.8 1.3 1.6 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain Orf78 PF06024.12 KER24171.1 - 0.047 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Death PF00531.22 KER24171.1 - 0.16 12.2 0.7 0.45 10.7 0.2 2.1 2 0 0 2 2 2 0 Death domain Ribosomal_S14 PF00253.21 KER24171.1 - 0.59 10.0 6.5 7.1 6.5 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e cEGF PF12662.7 KER24171.1 - 2.9 7.9 13.2 2.5 8.1 0.2 4.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like TatD_DNase PF01026.21 KER24173.1 - 1.3e-56 191.9 0.0 1.5e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase HCO3_cotransp PF00955.21 KER24175.1 - 6.8e-61 206.6 26.0 2.1e-32 112.6 10.2 3.1 2 1 1 3 3 3 3 HCO3- transporter family Band_3_cyto PF07565.13 KER24175.1 - 1.6e-33 116.7 0.0 8.8e-33 114.3 0.0 2.0 1 1 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.22 KER24175.1 - 0.098 12.6 0.0 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 ECH_1 PF00378.20 KER24179.1 - 8.5e-29 100.6 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER24179.1 - 2.6e-13 50.2 0.0 3.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Polyketide_cyc PF03364.20 KER24180.1 - 5.4e-26 91.3 0.1 7.1e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SIP PF04954.13 KER24181.1 - 0.00024 21.6 0.0 0.95 10.0 0.0 2.1 2 0 0 2 2 2 2 Siderophore-interacting protein GDA1_CD39 PF01150.17 KER24181.1 - 0.053 12.2 0.1 0.67 8.5 0.1 1.9 1 1 1 2 2 2 0 GDA1/CD39 (nucleoside phosphatase) family Transposase_23 PF03017.14 KER24181.1 - 0.082 12.9 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 TNP1/EN/SPM transposase Flocculin_t3 PF13928.6 KER24181.1 - 0.44 11.1 4.1 17 6.0 0.3 2.5 2 0 0 2 2 2 0 Flocculin type 3 repeat WW PF00397.26 KER24185.1 - 2e-10 40.6 7.8 4.4e-10 39.5 7.8 1.6 1 0 0 1 1 1 1 WW domain zf-U1 PF06220.12 KER24185.1 - 4.5e-09 35.9 0.7 8.1e-09 35.1 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger FlaC_arch PF05377.11 KER24185.1 - 2.7 8.5 5.6 1.7 9.1 2.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 KER24186.1 - 0.028 14.6 2.7 0.028 14.6 2.7 9.1 9 2 2 11 11 11 0 Homeobox associated leucine zipper SRR PF07709.11 KER24186.1 - 6.8 7.6 5.2 3.2 8.5 0.7 2.9 3 0 0 3 3 3 0 Seven Residue Repeat DUF5582 PF17819.1 KER24187.1 - 7.5e-05 23.2 0.2 0.00014 22.4 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 KER24187.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_7 PF13499.6 KER24187.1 - 0.14 12.7 0.1 0.34 11.4 0.0 1.8 2 1 0 2 2 2 0 EF-hand domain pair Bin3 PF06859.12 KER24189.1 - 4.5e-30 104.5 0.0 7.5e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KER24189.1 - 7e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER24189.1 - 7.1e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER24189.1 - 5.1e-07 29.7 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER24189.1 - 7e-07 29.9 0.0 2.6e-06 28.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER24189.1 - 4.5e-06 27.2 0.0 7.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KER24189.1 - 0.00091 18.8 0.0 0.0034 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KER24189.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PARG_cat PF05028.14 KER24190.1 - 2.4e-26 92.8 0.0 7.1e-23 81.4 0.0 2.9 2 1 0 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) Homeodomain PF00046.29 KER24192.1 - 7.9e-22 76.9 5.5 1.7e-21 75.8 5.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER24192.1 - 0.0051 16.7 0.2 0.02 14.8 0.2 2.1 1 0 0 1 1 1 1 Homeobox KN domain XAP5 PF04921.14 KER24193.1 - 5.5e-91 304.8 3.9 5.5e-91 304.8 3.9 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator Rootletin PF15035.6 KER24193.1 - 4.5 7.2 13.4 24 4.9 13.4 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TFIID-31kDa PF02291.15 KER24194.1 - 4.6e-11 42.9 0.1 7.8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit COesterase PF00135.28 KER24195.1 - 4.9e-72 243.4 1.6 3.4e-47 161.5 0.1 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KER24195.1 - 5.8e-05 23.0 0.1 0.00028 20.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold AAA PF00004.29 KER24196.1 - 9.8e-45 152.2 0.0 2.8e-38 131.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER24196.1 - 5e-08 33.5 0.9 0.021 15.2 0.1 4.0 2 2 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KER24196.1 - 2.7e-07 30.3 0.0 0.00087 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 KER24196.1 - 2.9e-06 27.6 0.0 0.0023 18.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KER24196.1 - 2.8e-05 24.1 0.0 0.0093 16.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KER24196.1 - 0.00022 21.0 0.0 0.021 14.6 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KER24196.1 - 0.00061 20.0 0.0 0.094 12.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KER24196.1 - 0.0037 16.7 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KER24196.1 - 0.0061 16.3 0.0 4.3 7.0 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KER24196.1 - 0.0068 16.3 0.1 6 6.7 0.0 3.1 2 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 KER24196.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KER24196.1 - 0.013 15.9 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KER24196.1 - 0.019 14.9 0.1 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 KER24196.1 - 0.028 13.6 0.0 15 4.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KER24196.1 - 0.082 12.8 0.0 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KER24196.1 - 0.1 12.6 0.0 9.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TMEM95 PF15203.6 KER24197.1 - 0.027 14.1 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 TMEM95 family PL48 PF15903.5 KER24200.1 - 7.7e-10 38.3 0.7 1.8e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Filopodia upregulated, FAM65 PID PF00640.23 KER24201.1 - 1.1e-09 38.5 0.1 3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KER24201.1 - 1.8e-08 34.3 0.0 6.8e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 SH2 domain PID_2 PF14719.6 KER24201.1 - 0.03 14.2 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Sporozoite_P67 PF05642.11 KER24201.1 - 1.8 6.6 12.0 3.2 5.7 12.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_25 PF13649.6 KER24202.1 - 0.0047 17.6 0.0 0.0072 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER24202.1 - 0.17 12.6 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EGF PF00008.27 KER24203.1 - 8.8e-11 41.9 29.4 6.2e-07 29.6 5.7 4.7 3 1 0 3 3 3 3 EGF-like domain EGF_2 PF07974.13 KER24203.1 - 5.4e-05 23.5 4.0 5.4e-05 23.5 4.0 4.4 4 1 0 4 4 4 2 EGF-like domain hEGF PF12661.7 KER24203.1 - 0.0001 22.8 29.9 0.0014 19.1 5.4 5.3 4 1 0 4 4 4 2 Human growth factor-like EGF cEGF PF12662.7 KER24203.1 - 4.2 7.4 15.3 0.7 9.9 2.4 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Pkinase_Tyr PF07714.17 KER24204.1 - 7e-96 320.5 0.0 1.1e-95 319.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER24204.1 - 9e-47 159.6 0.0 2.1e-46 158.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KER24204.1 - 9.7e-25 86.5 0.3 2e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 SH2 domain F_actin_bind PF08919.10 KER24204.1 - 2.4e-23 82.3 0.5 5.3e-23 81.2 0.5 1.6 1 0 0 1 1 1 1 F-actin binding Haspin_kinase PF12330.8 KER24204.1 - 0.019 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SH3_1 PF00018.28 KER24204.1 - 0.027 14.1 0.3 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 SH3 domain Kdo PF06293.14 KER24204.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-3CxxC PF13695.6 KER24205.1 - 9.6e-26 90.2 1.8 2.4e-25 88.9 1.8 1.7 1 0 0 1 1 1 1 Zinc-binding domain zf-Dof PF02701.15 KER24205.1 - 0.093 12.9 0.3 0.66 10.2 0.1 2.4 2 0 0 2 2 2 0 Dof domain, zinc finger zf-3CxxC_2 PF17180.4 KER24205.1 - 8 7.3 8.6 3.7 8.4 0.5 3.5 4 0 0 4 4 4 0 Zinc-binding domain Aldo_ket_red PF00248.21 KER24206.1 - 8.8e-29 100.6 0.2 1.2e-16 60.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Rota_NS6 PF04866.12 KER24206.1 - 0.058 13.6 0.3 0.18 12.0 0.2 1.8 1 1 0 1 1 1 0 Rotavirus non-structural protein 6 MRP-S22 PF10245.9 KER24207.1 - 2.4e-75 253.4 0.0 4e-75 252.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Mannosyl_trans PF05007.13 KER24207.1 - 9.4e-67 225.6 40.2 1.7e-29 103.5 3.6 3.3 2 1 1 3 3 3 3 Mannosyltransferase (PIG-M) DSPc PF00782.20 KER24207.1 - 4.1e-20 72.0 0.0 7.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PIG-U PF06728.13 KER24207.1 - 7.7e-12 44.9 6.8 7.7e-12 44.9 6.8 3.0 2 1 1 3 3 3 1 GPI transamidase subunit PIG-U DSPn PF14671.6 KER24207.1 - 0.015 15.7 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KER24207.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KER24207.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KdgT PF03812.13 KER24207.1 - 0.27 10.5 4.9 5.7 6.2 0.1 2.7 3 0 0 3 3 3 0 2-keto-3-deoxygluconate permease PRIMA1 PF16101.5 KER24207.1 - 4.2 7.4 5.3 1.6 8.7 0.2 2.9 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 RabGAP-TBC PF00566.18 KER24208.1 - 3.2e-38 131.5 0.3 1.7e-28 99.7 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GRAM PF02893.20 KER24208.1 - 4.9e-10 39.3 0.0 3e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 GRAM domain EF-hand_7 PF13499.6 KER24208.1 - 0.0069 16.8 0.1 0.32 11.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KER24208.1 - 0.0076 15.7 1.1 0.088 12.4 0.1 3.2 3 0 0 3 3 3 1 EF hand Pkinase PF00069.25 KER24209.1 - 2.7e-55 187.6 0.0 4e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24209.1 - 3.2e-23 82.3 0.0 5.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIIC_delta PF12657.7 KER24209.1 - 4.6e-07 29.9 0.0 8.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Kinase-like PF14531.6 KER24209.1 - 5.4e-05 22.6 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3450 PF11932.8 KER24209.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MULE PF10551.9 KER24210.1 - 2.1e-12 47.3 0.1 1.8e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 MULE transposase domain TraO PF10626.9 KER24212.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TraO PRELI PF04707.14 KER24213.1 - 4.7e-24 85.0 0.7 1e-23 83.9 0.7 1.6 1 1 0 1 1 1 1 PRELI-like family Autophagy_N PF03986.13 KER24213.1 - 2.2 8.2 3.9 1 9.3 0.5 2.1 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain WD40 PF00400.32 KER24215.1 - 3.9e-11 43.3 5.4 0.00047 20.9 0.1 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER24215.1 - 0.12 12.7 0.1 0.71 10.2 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Tetraspanin PF00335.20 KER24217.1 - 2e-79 266.5 64.5 2.1e-33 116.0 11.0 4.0 2 1 2 4 4 4 4 Tetraspanin family GnsAB_toxin PF08178.11 KER24217.1 - 0.08 12.9 0.1 15 5.6 0.0 2.7 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Tetraspanin PF00335.20 KER24219.1 - 1.4e-36 126.3 25.6 1.6e-36 126.1 25.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Sec23_helical PF04815.15 KER24219.1 - 0.09 12.6 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 Sec23/Sec24 helical domain DUF2975 PF11188.8 KER24219.1 - 1.6 8.6 15.4 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) RWP-RK PF02042.15 KER24221.1 - 0.16 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 RWP-RK domain Tetraspanin PF00335.20 KER24223.1 - 6.1e-27 94.8 8.3 8e-27 94.4 8.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Neurensin PF14927.6 KER24223.1 - 0.061 13.0 4.8 0.13 12.0 4.2 1.8 2 0 0 2 2 2 0 Neurensin Integrase_H2C2 PF17921.1 KER24225.1 - 0.13 12.4 0.9 0.23 11.6 0.9 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Peptidase_C37 PF05416.12 KER24226.1 - 0.14 10.7 4.0 0.16 10.4 4.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase TPP_enzyme_N PF02776.18 KER24227.1 - 1.9e-47 161.1 0.2 3.3e-47 160.3 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KER24227.1 - 1.1e-19 70.8 0.0 4.2e-19 68.8 0.0 2.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KER24227.1 - 8.3e-08 32.1 0.2 5.4e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KER24227.1 - 0.49 10.1 1.9 0.47 10.1 0.2 1.8 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GRIP PF01465.20 KER24228.1 - 3.9e-08 33.1 0.2 1.2e-07 31.5 0.2 2.0 1 0 0 1 1 1 1 GRIP domain Myosin_tail_1 PF01576.19 KER24228.1 - 3.2e-06 25.3 15.8 3.2e-06 25.3 15.8 6.6 4 2 2 6 6 6 2 Myosin tail TMF_TATA_bd PF12325.8 KER24228.1 - 0.00012 22.3 1.3 0.00012 22.3 1.3 16.3 7 5 10 17 17 17 3 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 KER24229.1 - 0.064 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 7tm_3 PF00003.22 KER24230.1 - 1.7e-51 175.3 17.9 1.7e-51 175.3 17.9 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR CEP76-C2 PF15627.6 KER24230.1 - 6.4e-39 133.0 0.0 1.1e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Gemini_C4 PF01492.17 KER24230.1 - 0.078 12.9 0.0 0.078 12.9 0.0 2.9 3 0 0 3 3 3 0 Geminivirus C4 protein Transglut_core PF01841.19 KER24230.1 - 0.097 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF5641 PF18701.1 KER24231.1 - 0.19 11.9 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5641) BAGE PF08180.11 KER24234.1 - 0.024 14.7 1.8 0.04 14.0 1.8 1.4 1 0 0 1 1 1 0 B melanoma antigen family 7tm_1 PF00001.21 KER24237.1 - 1.7e-10 40.7 14.0 2.3e-10 40.3 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1461 PF07314.11 KER24237.1 - 0.03 14.2 2.5 0.073 13.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Helicase_C PF00271.31 KER24238.1 - 0.0018 18.6 0.0 0.0067 16.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BTG PF07742.12 KER24239.1 - 1.5e-30 105.4 0.0 4.3e-30 103.9 0.0 1.7 2 0 0 2 2 2 1 BTG family Wbp11 PF09429.10 KER24240.1 - 4.7e-20 71.8 9.1 8.8e-20 70.9 9.1 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 DUF365 PF04033.12 KER24240.1 - 0.024 14.9 1.0 0.024 14.9 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Lipase_GDSL_2 PF13472.6 KER24241.1 - 1.4e-16 61.4 0.0 2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KER24241.1 - 4.7e-15 56.1 0.0 6.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SH3_9 PF14604.6 KER24242.1 - 6.9e-38 128.3 0.4 2.6e-12 46.4 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KER24242.1 - 7.4e-33 111.9 0.0 2e-13 49.7 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 KER24242.1 - 4.5e-28 96.7 0.0 2.7e-09 36.5 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain RhoGEF PF00621.20 KER24242.1 - 1.7e-24 87.1 0.4 3.8e-24 85.9 0.4 1.7 1 0 0 1 1 1 1 RhoGEF domain Renin_r PF07850.14 KER24242.1 - 1e-17 64.5 0.0 5.8e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Renin receptor-like protein PH_13 PF16652.5 KER24242.1 - 2.5e-13 50.1 0.0 2.5e-13 50.1 0.0 2.0 2 0 0 2 2 1 1 Pleckstrin homology domain EF-hand_4 PF12763.7 KER24242.1 - 1.7e-11 44.0 0.0 0.00013 21.8 0.0 3.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KER24242.1 - 8e-05 21.9 1.0 0.48 10.1 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER24242.1 - 0.00067 19.5 2.0 0.65 9.9 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KER24242.1 - 0.0017 18.1 1.3 7.6 6.8 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KER24242.1 - 0.0051 16.2 0.7 0.22 11.1 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KER24242.1 - 0.048 14.1 0.5 2.5 8.6 0.2 3.2 2 1 0 2 2 2 0 EF-hand domain pair DUF1664 PF07889.12 KER24242.1 - 2.1 8.4 5.4 21 5.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vitellogenin_N PF01347.22 KER24244.1 - 4e-37 128.0 13.4 4.3e-23 81.6 10.6 2.3 1 1 1 2 2 2 2 Lipoprotein amino terminal region DUF1943 PF09172.11 KER24244.1 - 9.8e-10 38.2 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) EGF_CA PF07645.15 KER24245.1 - 1.4e-08 34.8 27.0 1.1e-06 28.7 5.8 6.8 6 3 1 7 7 7 2 Calcium-binding EGF domain cEGF PF12662.7 KER24245.1 - 0.0014 18.5 1.5 0.0014 18.5 1.5 6.3 7 0 0 7 7 7 3 Complement Clr-like EGF-like Laminin_EGF PF00053.24 KER24245.1 - 0.008 16.3 12.1 0.008 16.3 12.1 7.0 2 1 4 6 6 6 1 Laminin EGF domain Glyco_transf_21 PF13506.6 KER24247.1 - 4.6e-39 133.7 0.2 8.2e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KER24247.1 - 2.2e-14 53.9 0.0 3.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KER24247.1 - 6e-06 26.3 6.0 6e-06 26.3 6.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KER24247.1 - 0.0033 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 CAP_C PF08603.11 KER24250.1 - 0.054 13.1 0.6 0.34 10.5 0.0 2.3 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) C terminal EF-hand_1 PF00036.32 KER24251.1 - 1.1e-08 34.1 0.0 0.0053 16.2 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER24251.1 - 4.6e-07 29.3 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER24251.1 - 5.4e-07 30.0 0.0 9.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER24251.1 - 0.00013 21.3 0.1 0.00033 20.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KER24251.1 - 0.00061 19.6 0.0 0.72 9.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KER24251.1 - 0.0052 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain Ribosom_S12_S23 PF00164.25 KER24254.1 - 7.7e-51 170.5 0.5 9.9e-51 170.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KER24254.1 - 0.098 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Myelin_PLP PF01275.19 KER24256.1 - 1.4e-26 93.8 30.7 3.8e-19 69.5 13.2 3.1 3 0 0 3 3 3 3 Myelin proteolipid protein (PLP or lipophilin) RVT_1 PF00078.27 KER24256.1 - 2.3e-06 27.3 0.0 9.3e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_1 PF00561.20 KER24256.1 - 0.022 14.4 0.1 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold SUIM_assoc PF16619.5 KER24256.1 - 0.23 11.6 0.1 38 4.5 0.0 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF5362 PF17319.2 KER24256.1 - 0.27 11.1 9.2 1.8 8.4 2.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5362) LRR_6 PF13516.6 KER24257.1 - 0.0079 16.2 1.3 0.02 14.9 0.1 2.4 2 0 0 2 2 2 1 Leucine Rich repeat LIM_bind PF01803.16 KER24257.1 - 0.081 12.4 0.8 0.13 11.8 0.8 1.2 1 0 0 1 1 1 0 LIM-domain binding protein RHH_5 PF07878.11 KER24257.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 LRR_6 PF13516.6 KER24258.1 - 1.2e-08 34.3 0.1 6.7e-06 25.7 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat R3H-assoc PF13902.6 KER24259.1 - 7.6e-18 65.2 0.6 1.6e-17 64.2 0.1 1.7 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KER24259.1 - 0.0068 16.4 0.0 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 R3H domain Pkinase PF00069.25 KER24261.1 - 1.6e-71 240.8 0.0 2.5e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24261.1 - 5.8e-33 114.3 0.0 9.6e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER24261.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER24261.1 - 0.0099 15.2 0.1 0.024 14.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L13 PF00572.18 KER24263.1 - 5.6e-20 71.8 0.0 7.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 ADK PF00406.22 KER24265.1 - 2.1e-51 174.0 0.0 2.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KER24265.1 - 4.1e-32 111.5 0.0 5.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KER24265.1 - 1.6e-09 38.4 0.0 2.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER24265.1 - 9.8e-08 32.3 0.1 2.1e-06 28.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KER24265.1 - 7.3e-07 29.0 0.1 0.023 14.4 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin PF02224.18 KER24265.1 - 0.01 15.6 0.6 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 KER24265.1 - 0.02 15.2 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PIN_12 PF16289.5 KER24265.1 - 0.025 15.1 0.8 0.044 14.3 0.7 1.4 2 0 0 2 2 1 0 PIN domain NTPase_1 PF03266.15 KER24265.1 - 0.034 14.0 0.1 0.21 11.5 0.0 2.1 2 1 0 2 2 2 0 NTPase Rsd_AlgQ PF04353.13 KER24265.1 - 0.045 13.7 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ AAA_22 PF13401.6 KER24265.1 - 0.053 13.8 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbsC_C PF18058.1 KER24265.1 - 0.09 13.0 0.6 0.14 12.4 0.6 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain AAA PF00004.29 KER24265.1 - 0.15 12.5 0.4 0.65 10.4 0.4 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KER24265.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.9 KER24266.1 - 5.9e-41 140.3 13.7 5.9e-41 140.3 13.7 2.6 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KER24266.1 - 3e-25 88.2 3.1 3e-25 88.2 3.1 3.6 4 0 0 4 4 4 1 JNK-interacting protein leucine zipper II Mto2_bdg PF12808.7 KER24266.1 - 0.076 13.3 4.2 1.3 9.4 0.7 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc7 PF08317.11 KER24266.1 - 1.1 8.1 20.3 0.16 10.8 6.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.12 KER24266.1 - 2.7 7.3 6.3 1 8.7 0.2 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.6 KER24266.1 - 4.1 6.7 8.9 0.37 10.1 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PKD_channel PF08016.12 KER24268.1 - 1.2e-110 370.1 12.6 1.2e-110 370.1 12.6 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 KER24268.1 - 3.3e-23 82.2 30.1 3.3e-23 82.2 30.1 2.3 2 0 0 2 2 2 1 Ion transport protein Tmemb_170 PF10190.9 KER24268.1 - 0.096 13.1 0.3 0.096 13.1 0.3 4.5 5 0 0 5 5 5 0 Putative transmembrane protein 170 EF-hand_1 PF00036.32 KER24268.1 - 0.099 12.2 0.2 2.4 7.9 0.1 3.2 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 KER24268.1 - 1.1 9.8 4.2 2.7 8.5 0.5 3.0 3 0 0 3 3 3 0 EF-hand domain pair CDC73_N PF16050.5 KER24269.1 - 1.9e-09 37.3 0.5 4.9e-09 35.9 0.5 1.6 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Pkinase PF00069.25 KER24270.1 - 3e-42 144.8 0.0 3.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24270.1 - 9.7e-15 54.5 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER24270.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 KER24271.1 - 8.5e-07 28.7 0.0 0.0076 15.9 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KER24271.1 - 0.0056 16.9 0.0 0.041 14.1 0.0 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KER24271.1 - 0.085 13.2 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KER24271.1 - 0.095 12.1 0.0 0.58 9.6 0.0 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 KER24271.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KER24272.1 - 0.0029 18.4 2.7 0.004 18.0 0.3 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40 PF00400.32 KER24273.1 - 4.3e-05 24.2 1.1 0.48 11.4 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER24273.1 - 0.00015 22.0 0.1 0.00052 20.3 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain MARVEL PF01284.23 KER24274.1 - 6.2e-20 71.7 9.3 7.8e-20 71.4 9.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3938 PF13074.6 KER24274.1 - 7 7.0 7.8 13 6.1 5.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3938) Trypsin PF00089.26 KER24275.1 - 1.7e-55 188.3 0.0 6.6e-53 179.8 0.0 2.1 2 0 0 2 2 2 2 Trypsin Helicase_RecD PF05127.14 KER24277.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase zf-met PF12874.7 KER24278.1 - 1.9e-14 53.5 14.3 1.1e-06 28.8 0.4 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER24278.1 - 8.9e-11 41.8 7.5 3.1e-05 24.1 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KER24278.1 - 0.00012 21.8 3.1 0.0017 18.0 0.2 2.5 2 0 0 2 2 2 1 U1 zinc finger zf-DBF PF07535.12 KER24278.1 - 0.0081 16.3 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 KER24278.1 - 0.025 15.4 9.2 0.96 10.5 0.5 4.6 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER24278.1 - 0.025 14.9 13.4 0.028 14.8 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-SCNM1 PF15803.5 KER24278.1 - 0.19 11.4 2.3 1.5 8.5 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 AKAP95 PF04988.12 KER24278.1 - 0.21 11.8 3.9 5.7 7.1 0.1 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_ZHX PF18387.1 KER24278.1 - 0.78 9.4 6.7 2.5 7.8 1.4 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KER24278.1 - 0.93 10.1 8.9 10 6.8 1.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Polyketide_cyc2 PF10604.9 KER24279.1 - 2.1e-05 24.8 0.0 2.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HicB_lk_antitox PF15919.5 KER24279.1 - 0.092 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system AHSA1 PF08327.11 KER24279.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein IMS_HHH PF11798.8 KER24280.1 - 0.038 14.3 0.1 12 6.5 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif MRPL52 PF18699.1 KER24281.1 - 8.3e-20 70.8 0.1 1.3e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Mitoribosomal protein mL52 Rib_hydrolayse PF02267.17 KER24282.1 - 9.3e-58 195.5 0.2 1.3e-57 195.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosyl cyclase Thioredoxin_15 PF18403.1 KER24282.1 - 0.008 16.1 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Rib_hydrolayse PF02267.17 KER24283.1 - 3.9e-58 196.7 0.0 4.9e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase LRR_6 PF13516.6 KER24284.1 - 6.6e-07 28.9 5.7 0.65 10.2 0.0 5.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 KER24284.1 - 0.037 14.5 7.7 1.7 9.2 1.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 KER24284.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair ANF_receptor PF01094.28 KER24285.1 - 9.5e-41 140.1 0.0 1.4e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 KER24285.1 - 1.4e-27 97.0 19.9 1.4e-27 97.0 19.9 2.2 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KER24285.1 - 2.5e-05 24.1 15.9 2.5e-05 24.1 15.9 2.9 2 1 1 3 3 3 1 Nine Cysteines Domain of family 3 GPCR LNS2 PF08235.13 KER24286.1 - 5e-96 320.5 0.0 7e-96 320.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RVT_1 PF00078.27 KER24286.1 - 5e-42 143.9 0.0 8.4e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipin_N PF04571.14 KER24286.1 - 1.5e-30 105.2 0.0 3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KER24286.1 - 3.7e-25 88.0 0.1 7.5e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain ACBP PF00887.19 KER24286.1 - 2.1e-14 53.5 0.0 5.2e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 KER24286.1 - 3.3e-09 37.1 0.0 2.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER24286.1 - 1.5e-08 34.8 0.1 3.6e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KER24286.1 - 4.8e-08 33.1 0.1 6.3e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KER24286.1 - 2.3e-07 31.3 0.0 5.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER24286.1 - 0.0013 19.1 0.0 0.027 15.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat CLU PF13236.6 KER24287.1 - 9.2e-85 284.0 0.0 1.5e-84 283.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KER24287.1 - 4.1e-51 173.5 0.0 7.6e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KER24287.1 - 1.3e-15 57.4 2.4 1.4e-09 38.1 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER24287.1 - 1.1e-06 28.3 0.5 0.15 12.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat CLU_N PF15044.6 KER24287.1 - 2.9e-06 27.5 0.1 1.4e-05 25.3 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_MalT PF17874.1 KER24287.1 - 4.4e-05 23.0 0.0 9.3e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 MalT-like TPR region DUF727 PF05303.12 KER24287.1 - 0.00014 21.9 0.0 0.0007 19.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_1 PF00515.28 KER24287.1 - 0.017 15.0 0.0 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER24287.1 - 0.021 14.9 0.3 78 3.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Sterile PF03015.19 KER24287.1 - 0.15 12.3 0.1 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Male sterility protein PS_Dcarbxylase PF02666.15 KER24289.1 - 4.3e-59 199.4 0.0 6.3e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase HNOB PF07700.15 KER24290.1 - 5.4e-41 140.3 0.0 9.7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KER24290.1 - 9.5e-36 123.1 0.1 1.9e-35 122.2 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KER24290.1 - 1.1e-28 100.2 0.4 1.1e-28 100.2 0.4 1.7 2 0 0 2 2 2 1 Heme NO binding associated HNOB PF07700.15 KER24292.1 - 1.2e-42 145.7 0.1 2.2e-42 144.8 0.1 1.5 1 0 0 1 1 1 1 Haem-NO-binding HNOBA PF07701.14 KER24292.1 - 3e-23 82.4 12.3 1.1e-07 31.6 0.2 3.7 3 1 1 4 4 4 3 Heme NO binding associated Guanylate_cyc PF00211.20 KER24292.1 - 4.9e-22 78.4 0.0 9.8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Sda PF08970.10 KER24292.1 - 0.027 14.2 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Sporulation inhibitor A DUF2067 PF09840.9 KER24292.1 - 0.051 13.1 0.3 3.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) P63C PF10546.9 KER24292.1 - 0.1 13.2 0.0 30 5.3 0.0 2.9 2 1 1 3 3 3 0 P63C domain EcsC PF12787.7 KER24292.1 - 0.31 10.7 3.3 5.7 6.5 0.5 2.2 1 1 1 2 2 2 0 EcsC protein family KxDL PF10241.9 KER24292.1 - 2.5 8.4 5.1 51 4.2 4.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein HNOB PF07700.15 KER24293.1 - 1.2e-45 155.4 0.4 2.1e-45 154.7 0.4 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KER24293.1 - 3.7e-36 124.5 0.0 7.8e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KER24293.1 - 4.1e-33 114.7 5.4 9.9e-33 113.4 3.5 2.5 2 1 0 2 2 2 1 Heme NO binding associated Cation_ATPase_N PF00690.26 KER24295.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF1376 PF07120.11 KER24296.1 - 0.073 13.4 0.6 0.36 11.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1376) DUF3328 PF11807.8 KER24296.1 - 0.077 12.8 0.9 0.11 12.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) CDC37_C PF08564.10 KER24296.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain RhoGAP PF00620.27 KER24297.1 - 7.5e-32 110.3 0.0 1.4e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KER24297.1 - 1.6e-07 31.1 0.9 3.9e-07 29.8 0.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KER24297.1 - 0.0049 17.2 0.4 0.013 15.8 0.4 1.7 1 0 0 1 1 1 1 C1 domain Zn_ribbon_17 PF17120.5 KER24297.1 - 0.25 11.0 3.6 0.56 9.9 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KER24297.1 - 0.56 10.3 2.1 2.2 8.5 2.1 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Med18 PF09637.10 KER24298.1 - 2.7e-05 24.2 0.0 5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Med18 protein Hexapep PF00132.24 KER24298.1 - 0.015 15.0 10.8 0.42 10.4 0.3 3.8 4 0 0 4 4 4 0 Bacterial transferase hexapeptide (six repeats) DUF5396 PF17374.2 KER24298.1 - 0.12 10.3 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) rve PF00665.26 KER24299.1 - 1.9e-06 28.1 0.0 4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER24299.1 - 0.0013 18.4 0.2 0.0044 16.8 0.0 2.0 3 0 0 3 3 3 1 Integrase core domain MLVIN_C PF18697.1 KER24299.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain BHD_3 PF10405.9 KER24300.1 - 8.6e-24 83.7 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KER24300.1 - 2.1e-18 65.9 0.1 4.8e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 RVT_1 PF00078.27 KER24300.1 - 2.3e-11 43.6 0.0 4.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BHD_2 PF10404.9 KER24300.1 - 6.5e-08 33.4 0.6 6.5e-08 33.4 0.6 4.3 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KER24300.1 - 0.006 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily DEAD_2 PF06733.15 KER24300.1 - 0.039 13.6 0.4 0.081 12.5 0.4 1.4 1 0 0 1 1 1 0 DEAD_2 CUB PF00431.20 KER24302.1 - 0.036 14.4 0.0 0.9 9.9 0.0 2.5 2 0 0 2 2 2 0 CUB domain Gemin6 PF06372.12 KER24303.1 - 1e-18 67.5 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 KER24303.1 - 0.026 14.6 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain Myosin_head PF00063.21 KER24305.1 - 1.1e-270 899.7 7.7 6.9e-236 784.7 0.0 3.1 3 0 0 3 3 3 2 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KER24305.1 - 1.1e-244 814.9 278.7 1.4e-244 814.5 278.7 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 KER24305.1 - 1.4e-07 31.2 0.1 3.2e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_6 PF12774.7 KER24305.1 - 0.092 11.7 3.8 0.13 11.2 0.2 2.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Vac_Fusion PF02346.16 KER24305.1 - 7.7 6.2 15.5 15 5.3 0.1 6.5 5 1 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 Strabismus PF06638.11 KER24306.1 - 0.064 11.9 0.9 0.061 12.0 0.9 1.0 1 0 0 1 1 1 0 Strabismus protein DUF4853 PF16145.5 KER24307.1 - 0.054 13.6 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) Cdc6_C PF09079.11 KER24310.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain PIP5K PF01504.18 KER24311.1 - 0.031 13.5 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase UbiA PF01040.18 KER24312.1 - 0.0086 15.4 1.7 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2417 PF10329.9 KER24312.1 - 0.065 12.6 0.7 0.094 12.1 0.7 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF2304 PF10066.9 KER24312.1 - 3.3 8.0 7.7 0.24 11.7 2.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2353 PF09789.9 KER24313.1 - 0.00081 18.8 3.7 0.0091 15.4 1.5 2.1 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) RILP PF11461.8 KER24313.1 - 0.0051 17.0 0.5 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 Rab interacting lysosomal protein Phage_GP20 PF06810.11 KER24313.1 - 0.058 13.2 1.2 3.7 7.3 0.4 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 NOG1_N PF17835.1 KER24313.1 - 0.11 12.4 0.5 13 5.8 0.0 2.2 2 0 0 2 2 2 0 NOG1 N-terminal helical domain Prefoldin PF02996.17 KER24313.1 - 0.32 10.9 4.6 0.66 9.9 1.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KER24313.1 - 0.37 10.8 5.3 0.3 11.1 1.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 KER24313.1 - 0.46 10.9 7.6 0.13 12.7 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 KER24313.1 - 0.58 10.2 3.7 3 7.9 0.3 2.3 2 0 0 2 2 2 0 DivIVA protein Prefoldin_2 PF01920.20 KER24313.1 - 1.2 9.2 5.6 2.1 8.4 1.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.6 KER24313.1 - 2.4 8.6 5.5 0.41 11.0 1.6 1.7 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 FliJ PF02050.16 KER24313.1 - 6.2 7.1 11.2 14 5.9 2.8 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein DUF58 PF01882.18 KER24314.1 - 0.026 14.8 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF58 WD40 PF00400.32 KER24316.1 - 0.013 16.3 0.6 18 6.4 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat eIF-5_eIF-2B PF01873.17 KER24317.1 - 1.1e-36 125.2 0.2 2.5e-36 124.1 0.2 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PapA_C PF16911.5 KER24317.1 - 0.047 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus GEN1_C PF18380.1 KER24317.1 - 0.31 12.0 2.6 0.27 12.1 0.8 1.7 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain zf-C2H2 PF00096.26 KER24318.1 - 2.9e-09 36.9 23.2 6e-05 23.3 1.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER24318.1 - 3.4e-07 30.6 22.8 0.0037 18.0 1.6 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER24318.1 - 4.7e-07 30.0 0.9 4.7e-07 30.0 0.9 4.3 5 0 0 5 5 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER24318.1 - 0.0087 16.0 1.2 0.0087 16.0 1.2 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KER24318.1 - 0.022 14.4 10.7 0.63 9.7 0.8 3.5 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain TF_Zn_Ribbon PF08271.12 KER24318.1 - 0.053 13.0 12.3 0.25 10.9 1.6 3.3 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KER24318.1 - 0.16 11.9 8.1 3.9 7.5 0.7 2.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain ADK_lid PF05191.14 KER24318.1 - 0.2 11.6 7.2 0.96 9.5 1.5 3.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.21 KER24318.1 - 0.26 11.5 15.5 0.16 12.1 11.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger FpoO PF10621.9 KER24318.1 - 0.39 11.1 5.5 12 6.3 3.7 2.5 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO DUF3664 PF12406.8 KER24318.1 - 0.47 11.1 4.1 0.22 12.2 1.3 1.9 2 0 0 2 2 1 0 Surface protein Zn-ribbon_8 PF09723.10 KER24318.1 - 0.81 9.9 10.6 6.3 7.0 0.0 3.5 2 1 2 4 4 4 0 Zinc ribbon domain DZR PF12773.7 KER24318.1 - 2.1 8.4 11.3 1.8e+02 2.2 11.3 3.1 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 KER24318.1 - 2.4 8.0 8.7 8.5 6.2 0.2 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf_UBZ PF18439.1 KER24318.1 - 8.2 6.1 10.9 1.3 8.7 0.5 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger HECT PF00632.25 KER24319.1 - 1.6e-63 215.0 0.0 6e-63 213.2 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 KER24319.1 - 9.4e-44 147.8 8.7 1.3e-13 51.3 0.1 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KER24319.1 - 8.2e-24 82.9 14.9 4.3e-06 26.4 0.9 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C14 PF00656.22 KER24320.1 - 2.9e-41 142.1 0.0 3.5e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Acyltransferase PF01553.21 KER24321.1 - 9.5e-10 38.2 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KER24321.1 - 4.5e-08 33.1 0.0 9.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus SNF2_N PF00176.23 KER24322.1 - 5e-55 186.6 0.3 8.5e-55 185.9 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1086 PF06461.11 KER24322.1 - 2.8e-19 69.3 0.0 7.5e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) CHDCT2 PF08074.11 KER24322.1 - 1.8e-18 67.3 2.5 1.8e-18 67.3 2.5 3.9 3 1 0 3 3 3 1 CHDCT2 (NUC038) domain Helicase_C PF00271.31 KER24322.1 - 2.3e-16 60.1 0.0 5.2e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KER24322.1 - 1.9e-09 37.3 0.2 0.002 18.0 0.0 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KER24322.1 - 5.6e-07 29.7 0.0 1.7e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KER24322.1 - 0.00067 19.5 0.0 0.0024 17.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KER24322.1 - 0.044 14.1 0.0 0.19 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain bZIP_Maf PF03131.17 KER24323.1 - 1.8e-17 63.6 14.7 2.9e-17 63.0 14.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KER24323.1 - 2.2e-05 24.4 13.0 3.6e-05 23.8 13.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Bap31_Bap29_C PF18035.1 KER24323.1 - 0.056 13.4 0.7 0.056 13.4 0.7 1.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain IFT46_B_C PF12317.8 KER24323.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Cut12 PF11500.8 KER24323.1 - 0.21 11.5 4.4 0.33 10.9 4.4 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Phlebovirus_NSM PF07246.11 KER24323.1 - 0.34 10.3 2.7 0.45 9.8 2.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M bZIP_2 PF07716.15 KER24323.1 - 0.6 10.2 12.9 1.3 9.2 12.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Exonuc_VII_L PF02601.15 KER24323.1 - 0.71 9.4 4.0 0.97 8.9 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynein_light PF01221.18 KER24325.1 - 6.4e-26 90.5 0.1 7.7e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 KER24325.1 - 0.062 13.3 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 RNR_N PF08343.10 KER24325.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal V_ATPase_I PF01496.19 KER24332.1 - 0 1129.9 0.1 1.6e-276 919.5 0.0 3.1 2 1 1 3 3 3 3 V-type ATPase 116kDa subunit family ApoC-I PF04691.12 KER24332.1 - 0.001 18.9 0.4 0.0023 17.8 0.4 1.6 1 0 0 1 1 1 1 Apolipoprotein C-I (ApoC-1) MerR_2 PF13591.6 KER24332.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein Lipid_DES PF08557.10 KER24334.1 - 1e-17 63.3 0.8 1.9e-17 62.5 0.8 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 KER24334.1 - 1.3e-13 51.4 20.5 1.9e-13 50.8 20.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Metallopep PF12044.8 KER24334.1 - 0.099 11.2 0.5 0.14 10.7 0.5 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 KER24334.1 - 1.7 7.6 4.9 0.43 9.5 0.2 1.9 2 0 0 2 2 2 0 Peptidase M66 Keratin_matx PF04579.12 KER24335.1 - 0.022 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein MalM PF07148.12 KER24335.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) RAM PF15320.6 KER24336.1 - 2.8e-12 47.1 0.0 3.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein Glycolytic PF00274.19 KER24337.1 - 6.5e-180 597.3 0.0 7.5e-180 597.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Med1 PF10744.9 KER24339.1 - 4.6e-07 29.2 0.0 2.3e-05 23.6 0.0 2.5 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 zf-C2H2 PF00096.26 KER24341.1 - 3.8e-14 52.3 17.3 4.2e-06 26.9 0.6 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER24341.1 - 1.1e-07 31.9 20.1 1.2e-05 25.5 2.5 5.5 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER24341.1 - 7.4e-05 23.3 17.1 0.004 17.9 0.5 4.4 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER24341.1 - 8.3e-05 22.5 9.1 0.0082 16.1 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER24341.1 - 0.00039 20.1 5.1 0.013 15.2 0.0 3.7 3 0 0 3 3 3 1 zinc-finger C2H2-type APP_N PF02177.16 KER24341.1 - 0.0041 17.5 0.2 0.035 14.5 0.0 2.3 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding zf_UBZ PF18439.1 KER24341.1 - 0.0061 16.1 0.6 0.099 12.3 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 KER24341.1 - 0.018 15.1 0.2 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 CpXC protein OrfB_Zn_ribbon PF07282.11 KER24341.1 - 0.16 11.9 4.9 0.42 10.6 0.0 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KER24341.1 - 3.5 7.2 6.9 2 7.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KER24341.1 - 4.4 7.5 7.2 2.2 8.5 0.0 2.9 3 0 0 3 3 2 0 Zinc ribbon domain VWA PF00092.28 KER24343.1 - 1.7e-11 44.7 0.0 5.4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain GramPos_pilinD1 PF16555.5 KER24343.1 - 0.00075 19.7 0.9 1.7 8.8 0.1 2.8 2 0 0 2 2 2 2 Gram-positive pilin subunit D1, N-terminal domain VWA_2 PF13519.6 KER24343.1 - 0.027 15.1 0.0 0.073 13.7 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain RNase_H2_suC PF08615.11 KER24344.1 - 3e-08 33.9 0.0 2e-05 24.8 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GNAT_acetyltr_2 PF13718.6 KER24345.1 - 2.5e-92 308.4 0.0 7.7e-64 215.2 0.0 2.9 2 1 1 3 3 3 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 KER24345.1 - 5.9e-52 176.1 0.0 1.4e-51 174.9 0.0 1.7 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 KER24345.1 - 3e-36 125.3 0.2 3e-36 125.3 0.2 3.2 3 0 0 3 3 3 2 Possible tRNA binding domain DUF1726 PF08351.11 KER24345.1 - 7.4e-33 112.4 0.0 2.1e-32 110.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 KER24345.1 - 0.023 15.1 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KER24345.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Myc_N PF01056.18 KER24345.1 - 0.13 12.1 15.4 0.93 9.3 1.6 2.4 2 0 0 2 2 2 0 Myc amino-terminal region EF-hand_8 PF13833.6 KER24347.1 - 6.4e-13 48.3 0.6 1.2e-07 31.5 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KER24347.1 - 1.8e-11 42.7 8.1 2.4e-05 23.6 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KER24347.1 - 9.9e-11 40.7 5.5 0.00032 20.4 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KER24347.1 - 2.6e-10 39.3 1.9 3.6e-05 23.0 0.6 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER24347.1 - 8.2e-06 26.2 13.4 0.0031 17.9 4.7 4.2 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_4 PF12763.7 KER24347.1 - 3.4e-05 23.7 0.1 0.41 10.6 0.0 3.1 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand PD40 PF07676.12 KER24348.1 - 0.021 14.8 0.2 0.039 13.9 0.2 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PHD PF00628.29 KER24350.1 - 0.026 14.4 3.0 0.047 13.6 3.0 1.4 1 0 0 1 1 1 0 PHD-finger IL3 PF02059.15 KER24350.1 - 0.027 14.5 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Interleukin-3 TetR_C_1 PF02909.17 KER24350.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OrfB_Zn_ribbon PF07282.11 KER24350.1 - 3.2 7.7 5.9 8.7 6.4 3.4 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain ALGX PF16822.5 KER24351.1 - 0.011 15.5 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX AMP-binding PF00501.28 KER24352.1 - 5.9e-89 298.6 0.0 7.1e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER24352.1 - 0.048 14.6 0.0 0.19 12.7 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ASXH PF13919.6 KER24353.1 - 4.4e-14 52.7 2.1 1.5e-13 51.0 0.0 2.5 2 0 0 2 2 2 1 Asx homology domain SatRNA_48 PF17485.2 KER24354.1 - 0.021 14.0 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein Ribosomal_L32e PF01655.18 KER24355.1 - 4.5e-45 152.5 5.0 5.5e-45 152.2 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Peptidase_M14 PF00246.24 KER24357.1 - 1e-67 229.0 0.0 1.3e-67 228.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 KER24357.1 - 6.9e-07 29.4 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2817 PF10994.8 KER24357.1 - 0.14 11.5 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) SSXT PF05030.12 KER24358.1 - 8e-10 38.2 0.2 1.4e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Forkhead PF00250.18 KER24359.1 - 8e-39 131.8 0.1 1.4e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KER24359.1 - 2.6e-06 27.7 0.0 7.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF3791 PF12668.7 KER24359.1 - 0.036 14.1 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) PQ-loop PF04193.14 KER24360.1 - 1.8e-27 94.9 12.6 1.5e-17 63.1 0.2 3.1 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KER24360.1 - 5e-05 24.2 7.1 5.5e-05 24.0 3.9 2.2 1 1 1 2 2 2 2 ER lumen protein retaining receptor Jagunal PF07086.12 KER24360.1 - 0.12 12.4 6.0 0.036 14.1 2.6 1.8 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis PAS_3 PF08447.12 KER24362.1 - 1.8e-17 63.4 0.0 4.8e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KER24362.1 - 3e-14 53.1 0.0 1.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KER24362.1 - 6.1e-08 32.7 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.26 KER24362.1 - 0.00017 21.5 0.7 0.00058 19.8 0.9 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KER24362.1 - 0.00094 19.4 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KER24362.1 - 0.11 12.8 0.0 8.9 6.6 0.0 2.6 2 0 0 2 2 2 0 PAS fold Stork_head PF10264.9 KER24364.1 - 3.6e-14 52.7 0.0 3.2e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 Winged helix Storkhead-box1 domain TBPIP PF07106.13 KER24364.1 - 0.078 12.9 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Mss4 PF04421.13 KER24365.1 - 3.4e-24 84.8 0.0 6.7e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Mss4 protein Ig_3 PF13927.6 KER24366.1 - 7.1e-32 109.8 0.3 7.9e-05 23.2 0.1 8.9 8 1 0 8 8 8 5 Immunoglobulin domain I-set PF07679.16 KER24366.1 - 6.9e-20 70.9 0.0 0.0019 18.2 0.0 7.3 7 0 0 7 7 7 4 Immunoglobulin I-set domain ig PF00047.25 KER24366.1 - 7.2e-19 67.8 1.1 0.045 13.9 0.0 9.4 8 1 0 8 8 8 4 Immunoglobulin domain Ig_2 PF13895.6 KER24366.1 - 4.5e-17 62.1 0.9 0.046 14.1 0.0 8.8 9 1 0 9 9 9 3 Immunoglobulin domain V-set PF07686.17 KER24366.1 - 9.5e-17 61.1 0.0 6.3e-06 26.3 0.0 7.3 8 0 0 8 8 8 2 Immunoglobulin V-set domain fn3 PF00041.21 KER24366.1 - 3e-07 30.7 0.0 0.0023 18.2 0.2 3.2 2 1 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.12 KER24366.1 - 1.7e-05 24.8 0.0 0.012 15.6 0.0 3.7 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KER24366.1 - 0.0072 15.9 0.0 2 8.0 0.0 3.2 3 0 0 3 3 3 1 Immunoglobulin domain V-set_CD47 PF08204.11 KER24366.1 - 0.07 13.1 0.0 20 5.1 0.0 3.1 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain TNFR_16_TM PF18422.1 KER24367.1 - 0.1 12.6 0.3 0.1 12.6 0.3 2.9 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain RVT_1 PF00078.27 KER24368.1 - 7.3e-09 35.5 0.0 3e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Sucrose_synth PF00862.19 KER24369.1 - 0.00017 20.0 1.7 0.00017 20.0 1.7 2.1 2 1 0 2 2 2 1 Sucrose synthase ATG16 PF08614.11 KER24369.1 - 0.0064 16.7 14.4 0.0064 16.7 14.4 3.6 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) HTH_Tnp_Tc3_1 PF11427.8 KER24369.1 - 0.28 11.1 2.5 3.9 7.4 0.9 3.3 2 1 0 2 2 2 0 Tc3 transposase DUF745 PF05335.13 KER24369.1 - 0.34 10.6 34.3 0.042 13.6 9.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 KER24369.1 - 0.65 10.5 8.7 20 5.7 3.2 4.6 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein MICSWaP PF17018.5 KER24369.1 - 0.68 9.5 10.2 0.11 12.1 4.7 2.3 2 1 0 2 2 2 0 Spore wall protein FUSC PF04632.12 KER24369.1 - 0.97 7.9 25.2 1.4 7.3 7.0 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family PMC2NT PF08066.12 KER24369.1 - 2.8 8.7 11.2 2.4 8.9 2.4 3.8 2 1 0 3 3 3 0 PMC2NT (NUC016) domain Fib_alpha PF08702.10 KER24369.1 - 7.1 6.8 36.4 4.6 7.4 7.8 4.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Ig_3 PF13927.6 KER24370.1 - 0.0035 17.9 0.1 2.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER24370.1 - 0.0097 16.0 0.0 0.36 10.9 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin I-set domain C2-set_2 PF08205.12 KER24370.1 - 0.01 15.9 0.1 0.097 12.7 0.1 2.1 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 KER24372.1 - 5.2e-18 65.4 1.0 1.8e-05 25.3 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 KER24372.1 - 1.5e-12 47.4 0.0 0.00013 22.0 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KER24372.1 - 2.9e-10 40.3 0.2 0.07 13.5 0.0 3.6 3 1 1 4 4 4 3 Immunoglobulin domain ig PF00047.25 KER24372.1 - 4.8e-08 33.1 0.1 0.12 12.6 0.0 3.4 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER24372.1 - 3.6e-06 27.1 0.2 0.53 10.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER24372.1 - 7.1e-05 22.8 2.1 0.00025 21.1 0.2 2.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KER24372.1 - 0.001 18.6 0.0 0.29 10.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_4 PF16680.5 KER24372.1 - 0.0017 18.6 0.0 1.3 9.3 0.0 2.9 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 KER24372.1 - 0.041 14.3 0.2 0.21 12.0 0.0 2.2 3 0 0 3 3 3 0 Immunoglobulin C1-set domain fn3 PF00041.21 KER24373.1 - 5e-05 23.6 0.0 0.00017 21.9 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain DDE_3 PF13358.6 KER24374.1 - 0.0063 16.3 0.1 0.0096 15.7 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NTPase_1 PF03266.15 KER24377.1 - 8.2e-36 123.4 0.0 1.7e-34 119.2 0.0 2.3 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 KER24377.1 - 3.3e-07 30.9 0.0 7.1e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KER24377.1 - 5.7e-06 26.7 0.3 5.9e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KER24377.1 - 2e-05 24.1 0.0 0.062 12.6 0.0 2.1 2 0 0 2 2 2 2 KaiC AAA PF00004.29 KER24377.1 - 2.7e-05 24.6 0.0 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KER24377.1 - 0.00028 20.6 0.5 0.022 14.4 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 KER24377.1 - 0.00029 20.1 0.2 0.0008 18.7 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase RNA_helicase PF00910.22 KER24377.1 - 0.0003 21.2 0.0 0.0048 17.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KER24377.1 - 0.00038 20.4 0.1 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 KER24377.1 - 0.00053 19.9 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KER24377.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER24377.1 - 0.0018 18.5 0.0 0.0044 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KER24377.1 - 0.0023 17.9 0.2 0.088 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KER24377.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KER24377.1 - 0.0053 16.6 0.1 0.043 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KER24377.1 - 0.0074 16.0 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ParA PF10609.9 KER24377.1 - 0.0081 15.6 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Mg_chelatase PF01078.21 KER24377.1 - 0.013 14.9 0.1 0.033 13.6 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KER24377.1 - 0.02 13.9 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KER24377.1 - 0.024 14.2 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KER24377.1 - 0.031 14.2 0.4 0.1 12.5 0.1 2.0 2 1 1 3 3 3 0 RsgA GTPase AAA_19 PF13245.6 KER24377.1 - 0.032 14.6 0.2 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KER24377.1 - 0.034 14.4 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER24377.1 - 0.037 14.6 0.1 0.049 14.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KER24377.1 - 0.042 13.6 0.1 0.19 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KER24377.1 - 0.045 13.5 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KER24377.1 - 0.045 13.8 0.1 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KER24377.1 - 0.058 13.5 0.1 0.091 12.9 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 KER24377.1 - 0.063 12.7 0.2 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein APS_kinase PF01583.20 KER24377.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 KER24377.1 - 0.1 13.0 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KER24377.1 - 0.1 11.8 0.2 0.26 10.5 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KER24377.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 KER24377.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF5584 PF17822.1 KER24377.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5584) Ntox3 PF15536.6 KER24378.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 PheRS_DBD1 PF18552.1 KER24378.1 - 0.24 11.2 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 1 MIP PF00230.20 KER24379.1 - 1.8e-46 158.7 6.2 2.1e-46 158.5 6.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF1269 PF06897.12 KER24379.1 - 0.041 14.2 0.5 0.94 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF2070 PF09843.9 KER24379.1 - 0.11 10.8 0.2 0.17 10.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Presenilin PF01080.17 KER24380.1 - 4.2 6.0 7.7 5.8 5.6 7.7 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 KER24380.1 - 5.9 5.0 76.7 7.5 4.6 76.7 1.1 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.20 KER24382.1 - 2.1e-35 122.5 11.4 2.6e-35 122.2 11.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Na_H_antiport_2 PF13726.6 KER24382.1 - 0.99 9.6 7.0 2.4 8.4 0.2 3.3 3 1 1 4 4 4 0 Na+-H+ antiporter family MIP PF00230.20 KER24383.1 - 9.7e-34 117.0 15.4 1.1e-33 116.8 15.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein tRNA-synt_1 PF00133.22 KER24385.1 - 2.3e-228 759.4 0.0 3.1e-228 758.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KER24385.1 - 7.3e-29 100.7 0.0 5.1e-25 88.2 0.0 2.6 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KER24385.1 - 1.5e-11 43.7 0.3 0.00042 19.2 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KER24385.1 - 2.9e-05 23.6 0.0 9.7e-05 21.9 0.0 1.9 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain RF3_C PF16658.5 KER24385.1 - 0.00095 19.0 0.0 0.0083 15.9 0.0 2.2 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain DUF5038 PF16441.5 KER24385.1 - 0.02 14.9 0.0 2.4 8.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5038) CNDH2_M PF16869.5 KER24387.1 - 0.037 14.7 0.0 0.043 14.5 0.0 1.1 1 0 0 1 1 1 0 PF16858 EF-hand_1 PF00036.32 KER24389.1 - 1.3e-33 112.0 13.8 1.1e-09 37.2 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER24389.1 - 5.7e-28 97.2 8.2 7.6e-14 51.9 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER24389.1 - 1.7e-26 89.8 7.6 1.2e-07 31.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KER24389.1 - 2.3e-22 78.6 11.1 9e-13 47.9 1.8 3.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KER24389.1 - 1.1e-21 75.3 7.0 1.6e-06 27.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KER24389.1 - 2.6e-13 50.1 0.4 3.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KER24389.1 - 2e-11 43.8 3.5 0.0016 18.4 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER24389.1 - 3.7e-11 43.0 0.4 1.2e-05 25.4 0.0 2.7 2 1 1 3 3 3 3 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KER24389.1 - 6.1e-07 29.8 0.9 0.009 16.3 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KER24389.1 - 3.6e-05 23.7 2.4 0.092 12.7 0.0 2.4 1 1 2 3 3 3 2 Tellurite resistance protein TerB SurA_N_3 PF13624.6 KER24389.1 - 4.2e-05 23.4 0.4 0.0014 18.4 0.2 2.0 1 1 1 2 2 2 2 SurA N-terminal domain SurA_N_2 PF13623.6 KER24389.1 - 0.00015 21.7 0.5 0.0027 17.6 0.2 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Adenine_glyco PF03352.13 KER24389.1 - 0.0053 16.6 0.4 0.024 14.4 0.1 1.8 1 1 1 2 2 2 1 Methyladenine glycosylase Vps23_core PF09454.10 KER24389.1 - 0.008 16.1 0.1 0.37 10.8 0.0 2.8 2 1 0 2 2 2 1 Vps23 core domain Caleosin PF05042.13 KER24389.1 - 0.032 14.1 0.8 5.6 6.9 0.0 2.9 1 1 0 2 2 2 0 Caleosin related protein DUF1707 PF08044.11 KER24389.1 - 0.039 14.0 2.1 0.29 11.2 0.1 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_14 PF17959.1 KER24389.1 - 0.12 12.8 0.8 10 6.5 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain DUF1456 PF07308.13 KER24389.1 - 0.13 12.7 0.4 16 5.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_10 PF14788.6 KER24389.1 - 0.79 9.6 4.2 0.56 10.1 0.5 2.5 2 1 1 3 3 3 0 EF hand DUF4834 PF16118.5 KER24389.1 - 3.6 8.6 9.4 1.4 9.9 2.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) RVT_1 PF00078.27 KER24392.1 - 3e-05 23.6 0.0 3.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH_repeat PF18780.1 KER24392.1 - 0.11 12.3 1.3 0.19 11.6 1.3 1.4 1 0 0 1 1 1 0 Homing endonuclease repeat PRCC PF10253.9 KER24393.1 - 0.00045 21.1 7.8 0.00045 21.1 7.8 2.8 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting RcsD_ABL PF16359.5 KER24395.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 RcsD-ABL domain DUF4837 PF16125.5 KER24395.1 - 0.13 11.2 0.2 0.16 11.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Thioredoxin PF00085.20 KER24396.1 - 2.4e-19 69.2 0.0 4.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KER24396.1 - 0.00039 20.8 0.0 0.0032 17.9 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KER24396.1 - 0.01 16.2 0.0 0.16 12.3 0.0 2.7 3 1 1 4 4 4 1 Thioredoxin-like RVT_1 PF00078.27 KER24396.1 - 0.03 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin_7 PF13899.6 KER24396.1 - 0.056 13.6 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Utp11 PF03998.13 KER24397.1 - 9.4e-38 130.5 17.4 1.3e-37 130.1 17.4 1.2 1 0 0 1 1 1 1 Utp11 protein Lzipper-MIP1 PF14389.6 KER24397.1 - 0.25 11.7 8.6 0.34 11.2 0.2 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 FliD_N PF02465.18 KER24397.1 - 3.8 8.3 6.6 11 6.8 1.2 2.6 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SBF PF01758.16 KER24398.1 - 2.2e-28 99.2 5.7 2.2e-28 99.2 5.7 2.1 1 1 1 2 2 2 1 Sodium Bile acid symporter family Pkinase_Tyr PF07714.17 KER24399.1 - 1.4e-84 283.4 0.0 2.5e-84 282.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER24399.1 - 3.7e-41 141.2 0.0 5.5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 KER24399.1 - 1.6e-11 43.6 0.8 3.4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KER24399.1 - 3.5e-11 42.8 0.0 7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER24399.1 - 8.3e-08 31.8 0.0 2.8e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH2 PF00017.24 KER24399.1 - 2.1e-06 27.7 0.0 5.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KER24399.1 - 0.00054 19.0 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER24399.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KER24399.1 - 0.045 13.3 0.1 0.24 11.0 0.0 2.1 3 0 0 3 3 3 0 RIO1 family APH PF01636.23 KER24399.1 - 0.057 13.3 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family EB1 PF03271.17 KER24400.1 - 1.5e-08 34.7 1.0 3.1e-08 33.7 1.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif DIX PF00778.17 KER24401.1 - 3.9e-30 103.5 0.0 6.5e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 KER24401.1 - 4.5e-21 75.3 0.1 1.1e-19 70.9 0.1 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 KER24401.1 - 5.1e-12 45.7 0.0 3.3e-11 43.1 0.0 2.5 1 0 0 1 1 1 1 Axin beta-catenin binding domain RRN3 PF05327.11 KER24405.1 - 7e-31 107.4 3.7 1.7e-29 102.8 3.7 2.0 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 AAA_5 PF07728.14 KER24406.1 - 3.6e-98 325.0 0.0 2e-23 82.9 0.0 8.3 9 0 0 9 9 8 6 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KER24406.1 - 2.5e-43 146.6 4.3 3e-14 53.1 0.1 5.6 6 0 0 6 6 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KER24406.1 - 6.7e-24 84.0 0.2 2.4e-22 79.0 0.0 3.5 3 0 0 3 3 3 1 Midasin AAA lid domain AAA_3 PF07726.11 KER24406.1 - 2.4e-22 79.2 0.0 1.1e-08 35.0 0.0 6.4 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KER24406.1 - 9.7e-22 77.4 0.0 0.00014 21.4 0.0 5.6 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA PF00004.29 KER24406.1 - 1.9e-19 70.4 0.0 9e-05 22.9 0.0 6.0 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER24406.1 - 1.4e-18 67.9 14.5 0.0012 19.2 0.1 8.6 7 2 0 7 7 7 4 AAA ATPase domain AAA_22 PF13401.6 KER24406.1 - 2.2e-16 60.3 3.5 0.01 16.1 0.0 6.9 5 1 0 5 5 5 4 AAA domain TsaE PF02367.17 KER24406.1 - 8.2e-11 42.0 0.6 0.62 10.1 0.0 5.9 5 0 0 5 5 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KER24406.1 - 3.5e-10 39.8 0.0 0.2 11.3 0.0 5.5 5 0 0 5 5 5 2 Sigma-54 interaction domain Dynein_heavy PF03028.15 KER24406.1 - 3.7e-10 39.9 0.7 0.011 15.8 0.0 6.2 7 0 0 7 7 5 2 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KER24406.1 - 4.3e-10 39.1 0.4 0.13 11.2 0.0 6.8 8 0 0 8 8 7 1 Hydrolytic ATP binding site of dynein motor region Sigma54_activ_2 PF14532.6 KER24406.1 - 5.1e-10 39.6 0.1 0.0025 17.9 0.0 5.1 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_30 PF13604.6 KER24406.1 - 1.9e-09 37.5 0.0 0.013 15.3 0.0 5.5 6 0 0 6 6 6 2 AAA domain AAA_18 PF13238.6 KER24406.1 - 1.8e-08 35.0 0.4 1.3 9.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain AAA_14 PF13173.6 KER24406.1 - 2e-07 31.1 0.0 1.5 8.9 0.0 6.0 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 KER24406.1 - 4.6e-07 30.4 1.2 1.1 9.7 0.0 5.8 6 0 0 6 6 5 2 ABC transporter Mg_chelatase PF01078.21 KER24406.1 - 4.9e-06 26.1 0.5 11 5.3 0.1 6.7 7 1 0 7 7 7 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KER24406.1 - 5.7e-06 26.7 0.3 13 6.2 0.0 5.5 5 0 0 5 5 5 0 RNA helicase Zeta_toxin PF06414.12 KER24406.1 - 1.2e-05 24.7 0.0 1.8 7.8 0.0 4.7 5 0 0 5 5 5 1 Zeta toxin AAA_8 PF12780.7 KER24406.1 - 1.7e-05 24.3 0.0 6.3 6.0 0.0 4.6 5 0 0 5 5 4 0 P-loop containing dynein motor region D4 DUF815 PF05673.13 KER24406.1 - 2.6e-05 23.5 1.1 0.13 11.4 0.0 4.0 5 0 0 5 5 4 2 Protein of unknown function (DUF815) NACHT PF05729.12 KER24406.1 - 2.8e-05 24.1 0.9 6 6.8 0.0 5.9 5 0 0 5 5 5 0 NACHT domain PduV-EutP PF10662.9 KER24406.1 - 4.2e-05 23.3 1.7 0.23 11.2 0.0 4.7 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KER24406.1 - 6.1e-05 23.0 0.1 7.6 6.4 0.0 4.4 5 0 0 5 5 4 0 RsgA GTPase Roc PF08477.13 KER24406.1 - 8.4e-05 22.8 0.1 19 5.5 0.0 4.5 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KER24406.1 - 9.3e-05 22.4 3.4 6.5 6.6 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_28 PF13521.6 KER24406.1 - 0.00011 22.5 4.2 1.8 8.8 0.1 5.1 4 0 0 4 4 4 1 AAA domain TniB PF05621.11 KER24406.1 - 0.00027 20.4 0.0 1.9 7.8 0.0 4.6 5 0 0 5 5 4 1 Bacterial TniB protein AAA_19 PF13245.6 KER24406.1 - 0.00049 20.5 3.8 3.7 7.9 0.0 4.7 5 0 0 5 5 3 1 AAA domain AAA_25 PF13481.6 KER24406.1 - 0.00071 19.2 5.4 1.9 8.0 0.0 5.4 7 0 0 7 7 5 1 AAA domain T2SSE PF00437.20 KER24406.1 - 0.00071 18.7 0.3 7.9 5.5 0.0 4.7 5 0 0 5 5 5 0 Type II/IV secretion system protein AAA_33 PF13671.6 KER24406.1 - 0.00072 19.7 0.6 1.9 8.7 0.0 4.7 5 0 0 5 5 5 1 AAA domain RuvB_N PF05496.12 KER24406.1 - 0.0013 18.5 0.1 5 6.9 0.0 4.8 5 0 0 5 5 5 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 KER24406.1 - 0.0029 17.7 0.1 11 6.1 0.0 4.3 4 0 0 4 4 4 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KER24406.1 - 0.003 17.5 0.0 2.3 8.1 0.0 4.3 5 0 0 5 5 5 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KER24406.1 - 0.0079 15.9 0.3 6.5 6.5 0.0 3.8 5 0 0 5 5 4 0 IstB-like ATP binding protein TIP49 PF06068.13 KER24406.1 - 0.0097 15.1 1.1 0.047 12.9 0.0 2.6 4 0 0 4 4 3 1 TIP49 P-loop domain AAA_24 PF13479.6 KER24406.1 - 0.014 15.1 0.0 8.1 6.1 0.0 3.9 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 KER24406.1 - 0.027 14.1 1.3 1.9 8.1 0.0 3.8 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain VWA_2 PF13519.6 KER24406.1 - 0.035 14.7 0.2 0.14 12.8 0.2 2.2 1 0 0 1 1 1 0 von Willebrand factor type A domain ATP_bind_1 PF03029.17 KER24406.1 - 0.085 12.6 1.2 19 4.9 0.0 4.0 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein dNK PF01712.19 KER24406.1 - 0.26 11.1 1.1 44 3.8 0.0 3.6 4 0 0 4 4 4 0 Deoxynucleoside kinase NTPase_1 PF03266.15 KER24406.1 - 0.82 9.6 3.1 85 3.0 0.0 4.2 5 0 0 5 5 5 0 NTPase DUF846 PF05832.12 KER24408.1 - 6e-46 155.9 6.1 8.1e-46 155.5 6.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Halogen_Hydrol PF10112.9 KER24408.1 - 0.28 11.2 3.6 5.5 7.0 0.7 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pkinase_Tyr PF07714.17 KER24409.1 - 1.4e-60 204.8 0.0 2e-58 197.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER24409.1 - 1.1e-27 97.1 0.0 1.2e-26 93.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.6 KER24409.1 - 5.4e-23 81.2 68.1 1e-06 28.6 5.4 7.4 6 1 0 7 7 7 6 Growth factor receptor domain IV Furin-like PF00757.20 KER24409.1 - 1.3e-06 28.4 78.2 0.00011 22.0 9.4 7.2 4 2 3 7 7 7 5 Furin-like cysteine rich region Recep_L_domain PF01030.24 KER24409.1 - 3.7e-05 23.8 0.1 8.3e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Receptor L domain GCM PF03615.15 KER24412.1 - 5.8e-66 220.7 2.0 1.1e-65 219.8 2.0 1.4 1 0 0 1 1 1 1 GCM motif protein Phosphodiest PF01663.22 KER24414.1 - 7.4e-47 160.7 0.4 5.5e-40 138.1 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.22 KER24416.1 - 1e-62 212.9 0.7 1.5e-62 212.3 0.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase IPK PF03770.16 KER24417.1 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF5544 PF17698.1 KER24418.1 - 0.009 16.1 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5544) Kunitz_BPTI PF00014.23 KER24421.1 - 3.5e-33 113.6 14.8 4.4e-18 65.3 4.7 2.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF5018 PF16410.5 KER24422.1 - 0.054 12.2 0.0 0.057 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Kunitz_BPTI PF00014.23 KER24423.1 - 9.4e-60 198.7 56.7 1e-17 64.1 9.7 4.2 4 0 0 4 4 4 4 Kunitz/Bovine pancreatic trypsin inhibitor domain SAD_SRA PF02182.17 KER24423.1 - 0.0016 18.1 5.9 5.1 6.8 0.1 3.5 4 0 0 4 4 4 3 SAD/SRA domain Toxin_2 PF00451.19 KER24423.1 - 0.042 14.2 2.9 0.042 14.2 2.9 5.1 5 0 0 5 5 5 0 Scorpion short toxin, BmKK2 DUF3873 PF12989.7 KER24423.1 - 0.047 14.1 0.3 0.047 14.1 0.3 3.0 4 0 0 4 4 4 0 Domain of unknown function, B. Theta Gene description (DUF3873) zf-RING_12 PF17976.1 KER24423.1 - 1.5 9.2 10.5 46 4.4 0.1 4.4 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain DUF5377 PF17347.2 KER24424.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5377) DUF5488 PF17590.2 KER24424.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Ion_trans PF00520.31 KER24425.1 - 5.9e-34 117.4 18.5 1.1e-33 116.5 18.5 1.4 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER24425.1 - 8.8e-29 99.7 0.0 2.1e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER24425.1 - 3.7e-10 39.6 5.4 3.7e-10 39.6 5.4 1.8 2 0 0 2 2 2 1 Ion channel EGF PF00008.27 KER24426.1 - 6.9e-05 23.1 25.0 0.0038 17.5 6.3 5.1 3 2 0 3 3 3 2 EGF-like domain EGF_2 PF07974.13 KER24426.1 - 0.0051 17.2 0.3 0.0051 17.2 0.3 4.7 4 1 0 4 4 4 2 EGF-like domain TSP_1 PF00090.19 KER24426.1 - 0.16 12.2 7.2 0.6 10.4 7.2 2.1 1 0 0 1 1 1 0 Thrombospondin type 1 domain hEGF PF12661.7 KER24426.1 - 0.21 12.3 18.4 4.7 8.0 0.3 5.0 4 0 0 4 4 4 0 Human growth factor-like EGF DUF1488 PF07369.11 KER24427.1 - 0.064 13.3 0.1 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) ig PF00047.25 KER24430.1 - 3.7e-13 49.5 0.1 2e-08 34.3 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER24430.1 - 7e-11 42.1 0.1 2.3e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KER24430.1 - 2.4e-10 40.8 2.4 4.2e-08 33.7 0.1 3.4 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 KER24430.1 - 3.7e-07 30.4 0.7 4.6e-05 23.7 0.2 3.0 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.12 KER24430.1 - 0.0012 18.9 0.0 0.094 12.8 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain KCNQ_channel PF03520.14 KER24432.1 - 1.4e-36 126.1 3.3 1.9e-36 125.7 0.9 2.2 2 1 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KER24433.1 - 5.7e-24 84.7 6.4 7.8e-24 84.2 6.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER24433.1 - 4e-13 49.1 3.3 4e-13 49.1 3.3 2.0 2 0 0 2 2 2 1 Ion channel IQ PF00612.27 KER24433.1 - 0.025 14.3 0.2 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Sensor PF13796.6 KER24434.1 - 0.077 13.0 0.1 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative sensor Calponin PF00402.18 KER24437.1 - 1.3e-60 200.6 46.1 9.1e-14 50.8 1.8 5.6 5 0 0 5 5 5 5 Calponin family repeat CH PF00307.31 KER24437.1 - 1.4e-14 54.1 0.0 1.8e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Calponin homology (CH) domain Pro_isomerase PF00160.21 KER24438.1 - 1.1e-20 74.5 0.0 1.8e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KER24438.1 - 1.7e-16 59.8 0.1 3.4e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_9 PF08221.11 KER24438.1 - 0.12 12.5 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain HCR PF07111.12 KER24440.1 - 6.2e-05 21.3 39.0 0.0001 20.6 39.0 1.3 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) Filament PF00038.21 KER24440.1 - 0.00044 19.9 11.1 0.00044 19.9 11.1 3.5 2 1 0 2 2 2 1 Intermediate filament protein Lebercilin PF15619.6 KER24440.1 - 0.0038 16.9 17.0 0.0038 16.9 17.0 3.8 3 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Spc42p PF11544.8 KER24440.1 - 0.11 12.5 4.0 0.58 10.2 3.0 2.9 1 1 0 1 1 1 0 Spindle pole body component Spc42p HPPK PF01288.20 KER24440.1 - 0.31 11.6 0.1 0.31 11.6 0.1 3.2 5 0 0 5 5 5 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) TPR_MLP1_2 PF07926.12 KER24440.1 - 1.2 9.2 57.1 0.11 12.5 4.3 5.2 3 3 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF916 PF06030.12 KER24440.1 - 1.7 8.7 4.9 1.5 8.9 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF916) FAM76 PF16046.5 KER24440.1 - 2.9 7.2 28.3 0.31 10.3 6.9 3.3 2 1 1 3 3 3 0 FAM76 protein Tmem26 PF09772.9 KER24441.1 - 0.007 15.8 0.1 0.0073 15.7 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 26 Tmem26 PF09772.9 KER24442.1 - 1.7e-06 27.6 2.2 2.4e-06 27.1 2.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 26 PAP2 PF01569.21 KER24442.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 PAP2 superfamily Piezo_RRas_bdg PF12166.8 KER24443.1 - 7.2e-109 364.9 0.0 1.9e-108 363.5 0.0 1.8 1 1 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 KER24443.1 - 3e-30 105.4 5.6 1.2e-24 87.1 2.9 2.4 1 1 1 2 2 2 2 Piezo Carb_anhydrase PF00194.21 KER24445.1 - 1.4e-59 201.7 0.0 1.5e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Glyco_hydro_39 PF01229.17 KER24445.1 - 0.23 10.0 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 TFCD_C PF12612.8 KER24447.1 - 8.2e-56 188.8 0.1 6.5e-55 185.9 0.0 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KER24447.1 - 7.5e-05 22.7 13.6 0.67 10.4 0.0 7.7 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 KER24447.1 - 8.5e-05 22.9 1.4 0.037 14.4 0.1 4.9 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KER24447.1 - 0.0028 18.1 6.3 1.1 9.8 0.3 5.7 5 1 2 7 7 7 1 HEAT-like repeat HEAT_PBS PF03130.16 KER24447.1 - 0.093 13.5 2.4 1.4 9.8 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat GTA_TIM PF13547.6 KER24448.1 - 0.084 12.1 0.1 0.21 10.9 0.1 1.5 1 1 0 2 2 2 0 GTA TIM-barrel-like domain DUF1604 PF07713.13 KER24449.1 - 0.073 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Laminin_G_3 PF13385.6 KER24450.1 - 7.2e-26 91.1 13.9 4.1e-05 23.8 0.1 5.9 6 0 0 6 6 6 5 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 KER24450.1 - 1.4e-09 38.3 2.4 4e-09 36.9 2.4 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 KER24450.1 - 5e-07 29.3 17.3 1e-06 28.2 17.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Daxx PF03344.15 KER24451.1 - 0.033 14.3 0.1 0.044 13.8 0.1 1.3 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain LSM PF01423.22 KER24452.1 - 1.7e-14 53.2 0.0 2.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KER24452.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain PEPCK_GTP PF00821.18 KER24456.1 - 1.7e-162 540.3 0.0 2.1e-162 540.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KER24456.1 - 3.2e-90 301.5 0.0 4.2e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Exo_endo_phos_2 PF14529.6 KER24458.1 - 8.7e-08 32.0 0.0 5.5e-07 29.5 0.0 2.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1160 PF06648.11 KER24458.1 - 1.8e-05 24.7 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1160) RVT_1 PF00078.27 KER24458.1 - 0.00066 19.3 0.2 0.0041 16.7 0.0 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin_2 PF14523.6 KER24458.1 - 0.0046 17.3 1.5 2 8.8 0.1 3.0 1 1 1 2 2 2 2 Syntaxin-like protein Myb_DNA-bind_6 PF13921.6 KER24458.1 - 0.014 15.6 0.1 1.9 8.8 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain O-antigen_lig PF13425.6 KER24459.1 - 0.44 9.3 0.8 0.49 9.1 0.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DNA_topoisoIV PF00521.20 KER24461.1 - 3.6e-113 378.7 0.0 6.1e-113 377.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KER24461.1 - 7.7e-46 155.5 1.2 1.8e-45 154.3 1.2 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KER24461.1 - 2.4e-25 89.0 0.5 4.8e-25 88.0 0.5 1.5 1 0 0 1 1 1 1 DNA gyrase B VWA PF00092.28 KER24461.1 - 1.5e-14 54.7 0.0 2.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Toprim PF01751.22 KER24461.1 - 1.5e-07 31.5 0.0 4.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 KER24461.1 - 3.4e-07 30.7 0.0 8.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VWA_2 PF13519.6 KER24461.1 - 4.7e-07 30.4 0.0 1.2e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain RVT_1 PF00078.27 KER24466.1 - 0.00013 21.5 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLC35F PF06027.12 KER24467.1 - 0.055 13.0 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Solute carrier family 35 SLC35F PF06027.12 KER24468.1 - 2.5e-15 56.8 7.8 2.8e-15 56.6 7.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 ARL6IP6 PF15062.6 KER24468.1 - 0.016 15.3 1.9 0.66 10.1 0.0 2.2 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix SLC35F PF06027.12 KER24469.1 - 1.1e-46 159.8 29.0 1.8e-45 155.8 29.0 2.2 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KER24469.1 - 8e-07 28.3 3.5 8e-07 28.3 3.5 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KER24469.1 - 4.1e-05 23.8 27.6 0.0021 18.2 0.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family PGM_PMM_I PF02878.16 KER24470.1 - 1.5e-20 73.3 0.1 5.3e-09 35.9 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KER24470.1 - 1.6e-05 25.0 0.0 4.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KER24470.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III TLD PF07534.16 KER24471.1 - 1.4e-08 35.1 0.1 5.6e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 TLD LysM PF01476.20 KER24471.1 - 1.5e-08 34.5 0.0 3.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 LysM domain PDGF_N PF04692.13 KER24471.1 - 0.014 16.1 3.3 4.3 8.2 0.3 2.7 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region TPR_15 PF13429.6 KER24473.1 - 0.00091 18.5 1.3 0.0097 15.1 0.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER24473.1 - 0.057 14.3 12.3 6.6 7.8 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER24473.1 - 0.059 13.1 0.0 0.58 9.9 0.4 2.3 2 0 0 2 2 2 0 TPR repeat DUF3090 PF11290.8 KER24473.1 - 0.088 12.6 0.8 0.23 11.3 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) PigN PF04987.14 KER24475.1 - 9.5e-92 308.2 33.8 9.5e-92 308.2 33.8 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KER24475.1 - 2.9e-14 53.5 0.9 6.4e-14 52.3 0.9 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KER24475.1 - 4.5e-05 22.9 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KER24475.1 - 0.0038 16.6 0.2 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KER24477.1 - 6e-09 36.0 0.0 7.8e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KER24477.1 - 0.041 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Phosphodiest PF01663.22 KER24478.1 - 0.00069 19.3 0.2 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase PigN PF04987.14 KER24479.1 - 9.6e-37 126.9 27.9 9.6e-37 126.9 27.9 3.0 3 0 0 3 3 3 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KER24479.1 - 3.3e-07 30.2 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KER24479.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily FAS_I_H PF18314.1 KER24480.1 - 0.013 15.2 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain PigN PF04987.14 KER24481.1 - 8e-08 31.6 0.5 1.4e-07 30.8 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) MARVEL PF01284.23 KER24481.1 - 0.024 14.7 7.5 0.043 13.9 7.5 1.3 1 0 0 1 1 1 0 Membrane-associating domain CECR6_TMEM121 PF14997.6 KER24481.1 - 0.031 14.1 0.8 0.052 13.4 0.4 1.5 1 1 0 1 1 1 0 CECR6/TMEM121 family EMP70 PF02990.16 KER24481.1 - 0.23 10.1 5.2 0.31 9.7 5.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 WD40 PF00400.32 KER24482.1 - 2.9e-41 138.7 24.1 5.5e-08 33.4 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER24482.1 - 9.4e-06 25.8 0.8 2.1 8.7 0.2 4.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER24482.1 - 0.0028 16.4 2.3 5 5.6 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KER24482.1 - 0.0038 16.6 0.0 0.59 9.4 0.0 2.4 2 1 1 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 KER24482.1 - 0.046 13.8 0.2 11 6.1 0.0 3.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RNase_P_p30 PF01876.16 KER24483.1 - 7.4e-26 91.0 0.0 3e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 RNase P subunit p30 TFIID_20kDa PF03847.13 KER24484.1 - 9.8e-17 61.2 0.1 1.5e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KER24484.1 - 0.00039 20.6 0.0 0.00066 19.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER24484.1 - 0.00092 19.6 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KER24484.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 KER24484.1 - 0.0057 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KER24484.1 - 0.047 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF1759 PF03564.15 KER24485.1 - 4.1e-12 46.3 0.0 6.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) SCVP PF17619.2 KER24486.1 - 0.018 15.8 0.1 8.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Secreted clade V proteins FBPase PF00316.20 KER24486.1 - 0.024 14.1 0.1 3.5 7.0 0.0 2.1 1 1 1 2 2 2 0 Fructose-1-6-bisphosphatase, N-terminal domain SET PF00856.28 KER24487.1 - 2e-11 44.6 0.4 3.9e-10 40.4 0.4 2.5 1 1 0 1 1 1 1 SET domain Rhodanese PF00581.20 KER24488.1 - 2e-09 37.9 0.0 4.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF4147 PF13660.6 KER24489.1 - 8e-54 182.6 0.0 1.4e-53 181.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 KER24489.1 - 5.4e-19 68.4 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 MOFRL family Sec23_trunk PF04811.15 KER24489.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain RNA_GG_bind PF10258.9 KER24490.1 - 2.8e-23 81.7 0.0 6e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain PHD PF00628.29 KER24491.1 - 0.00034 20.4 6.2 0.00076 19.3 6.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KER24491.1 - 0.13 12.2 2.9 0.33 10.9 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_Oberon PF07227.11 KER24491.1 - 0.26 11.2 6.1 0.43 10.5 6.1 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein C1_2 PF03107.16 KER24491.1 - 4.1 7.8 8.5 8.8 6.7 5.5 2.6 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 KER24491.1 - 5.4 7.0 7.8 1.5 8.7 3.8 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4218 PF13960.6 KER24492.1 - 0.022 14.3 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) E7 PF00527.18 KER24493.1 - 0.00014 22.0 2.6 0.29 11.3 0.2 2.1 1 1 1 2 2 2 2 E7 protein, Early protein dCMP_cyt_deam_1 PF00383.23 KER24493.1 - 0.0073 16.2 0.6 4.5 7.2 0.1 2.5 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region PT-TG PF14449.6 KER24493.1 - 0.0088 15.9 0.0 5.2 7.0 0.0 2.2 2 0 0 2 2 2 2 Pre-toxin TG Dehyd-heme_bind PF09098.10 KER24493.1 - 0.11 12.1 1.7 1.6 8.3 0.1 2.0 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Thioredoxin_3 PF13192.6 KER24493.1 - 0.28 11.3 3.3 14 5.9 0.2 2.7 2 2 0 2 2 2 0 Thioredoxin domain Pox_T4_N PF04491.12 KER24493.1 - 0.4 10.6 3.5 13 5.8 0.3 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus DUF4495 PF14906.6 KER24494.1 - 0.0001 21.5 1.8 0.00074 18.7 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4495) zf-C2H2 PF00096.26 KER24497.1 - 8.7e-11 41.7 20.9 0.00032 21.0 2.2 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER24497.1 - 2.3e-07 31.1 17.6 0.016 16.0 1.8 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER24497.1 - 0.00021 21.6 1.0 0.00021 21.6 1.0 4.4 3 1 1 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER24497.1 - 0.0012 18.8 11.0 0.068 13.2 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KER24497.1 - 0.038 14.4 9.2 0.44 11.0 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 KER24497.1 - 0.15 12.1 9.6 0.63 10.1 2.6 3.0 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.14 KER24497.1 - 0.25 11.3 3.0 3.7 7.6 0.1 2.6 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 KER24497.1 - 1.7 8.3 4.2 2.4 7.8 0.9 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CHY PF05495.12 KER24497.1 - 1.9 9.0 11.8 8.6 6.9 10.4 2.5 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.7 KER24497.1 - 2 8.8 11.2 14 6.1 0.3 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2 PF09337.10 KER24498.1 - 0.036 14.3 0.3 0.18 12.0 0.2 2.1 2 0 0 2 2 2 0 H2C2 zinc finger Serinc PF03348.15 KER24500.1 - 1.4e-22 80.3 6.4 2e-22 79.8 6.4 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Serinc PF03348.15 KER24501.1 - 3.4e-55 187.7 16.1 5e-55 187.2 16.1 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Nepo_coat_N PF03689.15 KER24501.1 - 0.097 12.6 0.0 27 4.8 0.0 2.8 2 1 0 2 2 2 0 Nepovirus coat protein, N-terminal domain AvrPtoB_bdg PF16847.5 KER24501.1 - 0.47 11.0 2.0 29 5.3 0.1 2.8 3 1 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain DUF1129 PF06570.11 KER24501.1 - 0.63 9.5 7.0 1 8.8 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) TMCO5 PF14992.6 KER24501.1 - 7 6.1 5.0 3.9 7.0 3.2 1.4 1 1 0 1 1 1 0 TMCO5 family ubiquitin PF00240.23 KER24502.1 - 2e-34 117.2 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KER24502.1 - 1.4e-30 104.9 12.4 2.2e-30 104.3 12.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KER24502.1 - 1.6e-16 59.9 0.5 2.6e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KER24502.1 - 1.6e-05 25.3 0.1 6.5e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KER24502.1 - 0.0032 17.8 0.1 0.0053 17.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KER24502.1 - 0.0052 16.7 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KER24502.1 - 0.007 16.5 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KER24502.1 - 0.015 15.3 1.2 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KER24502.1 - 0.027 15.0 0.0 0.033 14.8 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Thymidylate_kin PF02223.17 KER24505.1 - 1.4e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase zf-C2H2_11 PF16622.5 KER24507.1 - 0.096 12.5 0.3 0.096 12.5 0.3 1.5 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF267 PF03268.14 KER24508.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DBC1 PF14443.6 KER24510.1 - 3.9e-45 152.9 0.0 8.4e-45 151.8 0.0 1.5 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 KER24510.1 - 1.4e-09 37.5 0.3 2.9e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 SAP domain EF-hand_6 PF13405.6 KER24510.1 - 0.023 14.6 0.1 0.073 13.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KER24510.1 - 0.1 13.1 1.2 0.26 11.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF1456 PF07308.13 KER24510.1 - 0.12 12.7 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Mto2_bdg PF12808.7 KER24510.1 - 6.9 7.1 11.0 5.9 7.3 6.3 3.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Prominin PF05478.11 KER24510.1 - 7 4.5 5.2 1.4 6.8 1.3 1.6 2 0 0 2 2 2 0 Prominin CH_2 PF06294.11 KER24511.1 - 5.4e-11 42.5 0.2 2.7e-10 40.2 0.0 2.3 2 2 1 3 3 3 1 CH-like domain in sperm protein MRP-S26 PF14943.6 KER24511.1 - 0.48 10.3 11.1 0.68 9.8 11.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 AP1AR PF15745.5 KER24511.1 - 2.6 7.6 6.3 3.4 7.2 6.3 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein PAPS_reduct PF01507.19 KER24513.1 - 0.082 13.0 4.3 0.11 12.5 4.3 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family V_ATPase_I PF01496.19 KER24513.1 - 1.9 6.3 9.3 2.2 6.1 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADK PF00406.22 KER24514.1 - 1.2e-10 41.6 0.0 6.5e-06 26.3 0.0 3.1 2 1 1 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 KER24514.1 - 1.5e-05 25.5 0.6 0.0042 17.5 0.0 3.7 4 1 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KER24514.1 - 0.0051 17.4 0.0 0.062 13.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain Ndc1_Nup PF09531.10 KER24515.1 - 0.053 12.2 6.3 0.057 12.1 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KER24515.1 - 0.12 11.2 8.0 0.12 11.1 8.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mem_trans PF03547.18 KER24515.1 - 0.23 9.8 0.7 0.24 9.8 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.9 KER24515.1 - 0.8 8.2 8.9 0.95 7.9 8.9 1.1 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KER24515.1 - 1.1 7.3 12.2 1.3 7.0 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 KER24515.1 - 1.2 7.6 6.9 1.3 7.4 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 KER24515.1 - 3.7 6.2 12.7 5.1 5.7 12.7 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KER24515.1 - 9.4 6.2 9.6 13 5.7 9.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YtxH PF12732.7 KER24516.1 - 0.059 13.9 0.9 33 5.1 0.0 3.7 3 0 0 3 3 3 0 YtxH-like protein Archease PF01951.16 KER24516.1 - 0.51 10.6 2.1 23 5.2 0.2 3.2 2 2 0 2 2 2 0 Archease protein family (MTH1598/TM1083) KIF1B PF12423.8 KER24516.1 - 1.4 9.5 6.3 16 6.0 0.2 3.8 4 0 0 4 4 4 0 Kinesin protein 1B HalX PF08663.10 KER24516.1 - 6.2 7.2 11.6 16 5.9 1.5 3.7 3 0 0 3 3 3 0 HalX domain CxxCxxCC PF03692.15 KER24517.1 - 0.12 13.1 3.6 0.12 13.0 0.6 2.1 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain RVT_1 PF00078.27 KER24519.1 - 3e-21 76.0 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 KER24521.1 - 5.9e-24 84.6 15.5 8.1e-24 84.2 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily S4_2 PF13275.6 KER24523.1 - 0.00029 20.6 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 2 S4 domain SCA7 PF08313.12 KER24523.1 - 0.058 13.3 2.9 0.64 10.0 0.3 2.2 2 0 0 2 2 2 0 SCA7, zinc-binding domain DUF2729 PF10870.8 KER24523.1 - 0.21 11.4 0.9 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) Pkinase PF00069.25 KER24524.1 - 2.7e-64 217.1 0.0 6.2e-64 215.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24524.1 - 2.8e-37 128.4 0.0 1.2e-36 126.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase C2 PF00168.30 KER24524.1 - 1.2e-24 86.6 0.0 2.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 KER24524.1 - 1.5e-13 50.4 15.6 4.7e-13 48.8 15.6 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KER24524.1 - 0.019 14.3 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KER24524.1 - 0.061 12.2 0.0 0.2 10.6 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KER24524.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KER24524.1 - 0.17 11.5 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PHD PF00628.29 KER24524.1 - 1.3 9.0 11.1 3.2 7.7 11.1 1.7 1 0 0 1 1 1 0 PHD-finger RVT_1 PF00078.27 KER24525.1 - 3.3e-12 46.4 0.4 5.9e-11 42.3 0.2 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DIX PF00778.17 KER24527.1 - 4.2e-27 93.8 0.0 1.1e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 DIX domain RGS PF00615.19 KER24527.1 - 3e-20 72.6 0.0 5.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 KER24527.1 - 9.9e-05 22.4 1.6 9.9e-05 22.4 1.6 2.5 2 0 0 2 2 2 1 Axin beta-catenin binding domain SPARC_Ca_bdg PF10591.9 KER24528.1 - 2.2e-09 37.6 0.9 4.7e-09 36.6 0.9 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 KER24528.1 - 0.025 15.0 0.2 0.2 12.1 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain pair YqgB PF11036.8 KER24530.1 - 0.0055 16.4 0.0 4.7 7.0 0.0 2.3 2 0 0 2 2 2 2 Virulence promoting factor DUF3678 PF12435.8 KER24530.1 - 0.0099 15.2 0.7 0.031 13.6 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) IL17 PF06083.11 KER24530.1 - 0.066 13.7 0.0 6.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Interleukin-17 DUF3147 PF11345.8 KER24530.1 - 0.11 12.9 0.5 4.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Abhydrolase_1 PF00561.20 KER24531.1 - 4.7e-18 65.8 0.8 1e-17 64.6 0.8 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER24531.1 - 1.5e-07 31.0 0.1 0.00056 19.3 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KER24531.1 - 9.7e-05 21.9 0.1 0.00032 20.2 0.2 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.7 KER24531.1 - 0.0008 20.1 2.0 0.00099 19.8 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KER24531.1 - 0.019 14.6 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 KER24531.1 - 0.031 13.9 0.2 0.049 13.3 0.2 1.3 1 0 0 1 1 1 0 Putative esterase SDF PF00375.18 KER24533.1 - 3.5e-98 329.2 23.3 4e-98 329.0 23.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FERM_M PF00373.18 KER24534.1 - 3.2e-21 75.9 0.0 8.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 FERM central domain Kindlin_2_N PF18124.1 KER24534.1 - 1.2e-17 63.9 0.0 3.1e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Kindlin-2 N-terminal domain FERM_N PF09379.10 KER24534.1 - 0.0084 16.0 0.0 0.13 12.2 0.0 2.3 1 1 0 1 1 1 1 FERM N-terminal domain N2227 PF07942.12 KER24538.1 - 8.8e-94 313.7 0.0 4.6e-93 311.3 0.0 1.8 1 1 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KER24538.1 - 0.00018 22.1 0.0 0.0011 19.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER24538.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KER24538.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KER24538.1 - 0.079 13.7 0.0 0.41 11.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.16 KER24538.1 - 0.084 11.4 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 KER24538.1 - 0.17 12.6 0.0 3.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Dyp_perox PF04261.12 KER24539.1 - 1.6e-34 119.4 0.0 1.9e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family C2 PF00168.30 KER24540.1 - 1.9e-52 175.8 0.0 2.2e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.6 KER24540.1 - 0.0012 18.7 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.6 KER24540.1 - 0.0042 16.7 0.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 2 CEP76 C2 domain DUF4208 PF13907.6 KER24543.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) SAP18 PF06487.12 KER24544.1 - 8e-38 129.8 0.1 5e-37 127.2 0.0 2.2 2 0 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) AFT PF08731.11 KER24544.1 - 0.016 15.6 1.2 0.036 14.5 1.2 1.5 1 0 0 1 1 1 0 Transcription factor AFT Serpin PF00079.20 KER24545.1 - 6.2e-30 104.7 0.0 6.9e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) zf-H2C2_2 PF13465.6 KER24546.1 - 6.2e-21 73.8 44.1 1.5e-07 31.5 2.8 9.0 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER24546.1 - 6.4e-21 73.6 31.5 8.1e-05 22.9 0.7 7.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER24546.1 - 2.3e-14 52.9 33.9 0.034 15.0 3.4 7.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.12 KER24546.1 - 7.1e-08 32.6 19.9 0.0012 19.1 1.7 4.3 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KER24546.1 - 2.7e-06 27.5 11.5 0.088 13.1 0.0 6.0 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER24546.1 - 0.0013 19.0 13.5 1.1 9.8 0.1 5.7 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KER24546.1 - 0.012 15.2 0.2 0.012 15.2 0.2 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KER24546.1 - 0.015 15.3 31.8 0.33 11.0 1.8 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KER24546.1 - 0.08 12.9 18.1 0.096 12.6 2.0 3.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-BED PF02892.15 KER24546.1 - 0.1 12.6 16.9 2.4 8.3 1.1 5.2 2 1 3 5 5 5 0 BED zinc finger Elf1 PF05129.13 KER24546.1 - 0.21 11.6 13.6 0.42 10.7 2.1 4.2 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like DUF2225 PF09986.9 KER24546.1 - 0.88 9.3 3.9 1.3 8.7 1.9 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-TRAF PF02176.18 KER24546.1 - 1.6 9.5 13.6 0.061 14.0 1.6 3.1 3 0 0 3 3 2 0 TRAF-type zinc finger zinc_ribbon_15 PF17032.5 KER24546.1 - 8.4 7.2 11.6 23 5.8 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon family zf-C2H2_12 PF18658.1 KER24546.1 - 9.6 5.9 16.2 0.62 9.7 0.4 4.4 4 2 2 6 6 6 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KER24547.1 - 1.3e-19 69.7 40.0 1.5e-07 31.6 3.6 7.9 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER24547.1 - 6.7e-15 54.6 47.9 0.00029 21.1 0.7 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-Di19 PF05605.12 KER24547.1 - 8.9e-10 38.7 22.0 0.00012 22.3 1.3 4.0 3 1 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KER24547.1 - 1.4e-09 37.9 47.9 0.083 13.8 0.4 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER24547.1 - 8.3e-05 22.5 21.1 0.065 13.3 0.0 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER24547.1 - 0.00018 21.7 14.7 0.49 10.8 0.5 5.9 7 0 0 7 7 6 2 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 KER24547.1 - 0.06 13.2 4.4 0.4 10.5 0.2 2.7 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.9 KER24547.1 - 0.13 12.0 3.9 0.88 9.3 1.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-met PF12874.7 KER24547.1 - 0.38 11.2 22.1 0.61 10.6 0.1 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KER24547.1 - 1.6 8.5 17.1 4.3 7.2 0.0 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KER24547.1 - 3 8.0 22.9 0.12 12.6 2.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_12 PF18658.1 KER24547.1 - 7.2 6.3 17.4 0.52 9.9 1.3 4.6 3 2 2 5 5 5 0 Zinc-finger C2H2-type TRAF6_Z2 PF18048.1 KER24547.1 - 9.8 6.4 8.0 15 5.8 2.0 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Pkinase_Tyr PF07714.17 KER24548.1 - 7.1e-72 241.8 0.0 1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER24548.1 - 2e-42 145.4 0.0 3.8e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 KER24548.1 - 4.7e-16 58.8 0.1 8e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Kinase-like PF14531.6 KER24548.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like DUF4829 PF16111.5 KER24548.1 - 0.052 14.3 0.2 0.13 13.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) CcmD PF04995.14 KER24548.1 - 0.93 9.6 2.4 0.91 9.7 0.2 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Tropomodulin PF03250.14 KER24550.1 - 1.4e-58 196.9 4.4 1.4e-58 196.9 4.4 1.7 2 0 0 2 2 2 1 Tropomodulin YfhD PF14151.6 KER24550.1 - 0.045 13.9 0.3 0.12 12.5 0.3 1.7 1 0 0 1 1 1 0 YfhD-like protein Nif11 PF07862.11 KER24550.1 - 0.051 13.9 1.0 5.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Nif11 domain Raco_middle PF17651.1 KER24550.1 - 0.17 11.6 0.8 0.34 10.6 0.8 1.6 1 0 0 1 1 1 0 RACo middle region LRR_6 PF13516.6 KER24550.1 - 0.67 10.2 5.4 2.3 8.5 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat RHH_1 PF01402.21 KER24551.1 - 0.051 13.5 0.3 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family ThiF PF00899.21 KER24554.1 - 4e-61 206.5 0.0 7.8e-61 205.5 0.0 1.4 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KER24554.1 - 7.4e-20 71.3 0.1 3.3e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KER24554.1 - 2e-06 27.9 0.0 0.0057 16.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KER24554.1 - 0.00013 22.4 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KER24554.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KER24554.1 - 0.047 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KER24554.1 - 0.048 13.9 0.1 0.24 11.7 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KER24554.1 - 0.13 12.8 0.1 0.41 11.2 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PKD_channel PF08016.12 KER24556.1 - 3.4e-12 45.8 9.8 6.9e-12 44.8 9.8 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KER24556.1 - 2.6e-07 30.1 25.1 4.5e-07 29.4 25.1 1.4 1 0 0 1 1 1 1 Ion transport protein DUF1391 PF07151.12 KER24560.1 - 0.017 14.9 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Ribosomal_L11_N PF03946.14 KER24562.1 - 5.9e-24 83.7 0.3 1.4e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KER24562.1 - 2.1e-18 66.6 0.0 3.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain UCH PF00443.29 KER24564.1 - 6.7e-46 156.9 0.0 1.1e-45 156.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER24564.1 - 2.3e-27 96.4 2.3 8.7e-27 94.5 2.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RVT_1 PF00078.27 KER24566.1 - 2.7e-38 131.7 0.2 5.7e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KER24566.1 - 6.7e-25 87.4 0.0 2.6e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER24566.1 - 9.4e-23 80.1 0.0 4.6e-22 77.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KER24566.1 - 3.4e-21 75.6 0.0 1.2e-20 73.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain UQ_con PF00179.26 KER24566.1 - 1.1e-17 64.0 0.1 6.2e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Integrase_H2C2 PF17921.1 KER24566.1 - 4.9e-13 49.0 0.3 1.6e-12 47.4 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER24566.1 - 4.6e-05 23.1 0.0 0.00015 21.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KER24566.1 - 0.091 13.0 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PROCN PF08083.11 KER24567.1 - 2.4e-234 777.4 9.1 2.4e-234 777.4 9.1 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KER24567.1 - 4e-128 425.8 0.6 6.9e-128 425.0 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KER24567.1 - 5.8e-90 299.3 2.9 1.2e-89 298.3 2.9 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KER24567.1 - 1.2e-86 288.3 4.2 1.2e-86 288.3 4.2 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KER24567.1 - 1.8e-67 225.5 0.0 4e-67 224.4 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KER24567.1 - 9e-51 170.9 0.0 2e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 KER24567.1 - 4.8e-48 161.4 0.4 1.2e-47 160.2 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 KER24567.1 - 7.3e-09 35.6 0.0 2.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-C2H2 PF00096.26 KER24568.1 - 8.9e-09 35.3 8.8 0.0014 19.0 4.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER24568.1 - 2.6e-05 24.4 2.7 2.6e-05 24.4 2.7 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER24568.1 - 0.00087 19.9 13.0 0.11 13.4 0.1 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER24568.1 - 1 9.4 13.4 1.7 8.7 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Innexin PF00876.18 KER24569.1 - 6.6e-62 209.8 0.1 1.8e-60 205.1 0.1 2.2 1 1 0 1 1 1 1 Innexin Innexin PF00876.18 KER24570.1 - 5.4e-106 354.8 8.0 6.2e-106 354.6 8.0 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 KER24570.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF4381 PF14316.6 KER24570.1 - 0.11 12.7 4.4 0.77 10.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) RVT_1 PF00078.27 KER24571.1 - 3.9e-11 42.9 0.0 6.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IPK PF03770.16 KER24572.1 - 1.3e-35 123.0 0.1 3.4e-35 121.7 0.1 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Nop PF01798.18 KER24575.1 - 7.4e-80 267.7 0.0 1.6e-79 266.6 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KER24575.1 - 1.9e-20 73.0 4.0 1.9e-20 73.0 0.7 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain zf-B_box PF00643.24 KER24576.1 - 1.9e-07 31.1 4.8 1.9e-07 31.1 4.8 2.9 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 KER24576.1 - 2.8e-06 27.5 0.0 7.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 MATH domain YabA PF06156.13 KER24576.1 - 2.3 8.9 6.2 1.5 9.5 1.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA zf-RING_2 PF13639.6 KER24576.1 - 3.7 7.9 23.8 0.094 13.1 13.3 2.6 2 0 0 2 2 2 0 Ring finger domain Baculo_PEP_C PF04513.12 KER24576.1 - 5 7.2 13.7 0.1 12.6 3.8 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_38 PF13936.6 KER24577.1 - 4.1e-08 32.8 0.2 4.1e-08 32.8 0.2 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KER24577.1 - 1.2e-06 28.1 3.1 0.00018 21.2 0.4 2.8 2 1 1 3 3 3 2 Homeodomain-like domain HTH_32 PF13565.6 KER24577.1 - 7e-06 26.6 2.9 0.00047 20.7 0.7 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 KER24577.1 - 0.00019 21.2 0.4 0.00082 19.2 0.0 2.1 2 1 0 2 2 2 1 Tc3 transposase HTH_3 PF01381.22 KER24577.1 - 0.0072 16.4 1.4 3.2 7.9 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.18 KER24577.1 - 0.012 15.9 0.6 0.032 14.5 0.1 2.0 2 0 0 2 2 2 0 Transposase HTH_29 PF13551.6 KER24577.1 - 0.024 14.6 0.9 0.26 11.3 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 KER24577.1 - 0.03 14.5 1.8 2.1 8.6 0.2 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.7 KER24577.1 - 0.053 13.4 1.4 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 MarR family HTH_WhiA PF02650.14 KER24577.1 - 0.078 13.3 1.2 0.21 11.9 1.1 1.8 1 1 0 1 1 1 0 WhiA C-terminal HTH domain HTH_24 PF13412.6 KER24577.1 - 0.079 12.5 1.2 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KER24577.1 - 0.13 12.6 1.5 13 6.2 2.0 2.6 1 1 1 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 KER24577.1 - 0.15 12.0 0.1 25 4.9 0.0 2.6 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 KER24577.1 - 0.18 11.8 1.1 0.94 9.5 0.2 2.2 2 0 0 2 2 2 0 HTH domain DUF2362 PF10154.9 KER24578.1 - 1.2e-111 374.2 0.0 1.5e-111 373.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) ADH_N_2 PF16884.5 KER24578.1 - 0.022 14.6 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase RNA_polI_A14 PF08203.11 KER24578.1 - 0.26 12.0 1.3 1.2 9.9 0.2 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 EF-hand_1 PF00036.32 KER24579.1 - 8e-25 84.5 11.8 1.8e-08 33.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER24579.1 - 8.4e-24 83.8 9.3 2.8e-12 46.9 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER24579.1 - 1.1e-20 72.1 10.3 1.2e-06 27.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER24579.1 - 1.2e-20 71.6 8.5 4.3e-07 29.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KER24579.1 - 7.9e-14 51.3 9.8 0.0037 17.1 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER24579.1 - 1.5e-08 34.9 5.9 3.9e-05 23.9 0.4 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER24579.1 - 0.0017 18.7 0.1 1.4 9.3 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KER24579.1 - 0.002 18.0 1.9 0.11 12.5 0.3 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KER24579.1 - 0.005 16.7 9.3 0.032 14.1 0.1 3.6 4 0 0 4 4 4 1 EF hand Caleosin PF05042.13 KER24579.1 - 0.0056 16.6 1.0 8.2 6.3 0.1 3.5 1 1 3 4 4 4 1 Caleosin related protein Staphylokinase PF02821.16 KER24579.1 - 0.011 16.2 0.2 0.021 15.3 0.1 1.6 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family DUF4734 PF15881.5 KER24579.1 - 0.031 14.4 0.1 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) EF-hand_13 PF17958.1 KER24579.1 - 0.05 13.4 0.0 1.2 9.0 0.0 2.6 1 1 2 3 3 3 0 EF-hand domain DREPP PF05558.12 KER24579.1 - 0.059 13.3 0.2 0.09 12.7 0.2 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide MNE1 PF13762.6 KER24579.1 - 0.084 12.9 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial splicing apparatus component G-gamma PF00631.22 KER24581.1 - 4.3e-05 23.4 0.1 6.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 GGL domain IRK_C PF17655.1 KER24582.1 - 0.19 11.3 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain WW PF00397.26 KER24583.1 - 4.1e-07 30.0 0.1 1.1e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 WW domain DDE_Tnp_1_assoc PF13808.6 KER24584.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.8 2 0 0 2 2 2 0 DDE_Tnp_1-associated SNF2_N PF00176.23 KER24585.1 - 6.6e-65 219.1 0.0 1.5e-64 217.9 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER24585.1 - 2.2e-17 63.4 0.0 6.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyrophosphatase PF00719.19 KER24586.1 - 1.8e-35 122.1 0.0 2.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF4149 PF13664.6 KER24588.1 - 0.09 13.1 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Septin PF00735.18 KER24589.1 - 3.9e-114 380.7 6.7 3.6e-86 288.9 3.7 2.6 2 1 1 3 3 3 2 Septin FeoA PF04023.14 KER24589.1 - 0.0085 16.3 0.5 4.2 7.7 0.1 2.7 2 0 0 2 2 2 2 FeoA domain GTP_EFTU PF00009.27 KER24589.1 - 0.0098 15.4 0.1 0.0098 15.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UBA PF00627.31 KER24589.1 - 0.17 11.8 3.3 11 6.0 0.2 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Peptidase_S49 PF01343.18 KER24589.1 - 0.46 10.4 3.4 1.1 9.2 3.4 1.7 1 0 0 1 1 1 0 Peptidase family S49 Atg14 PF10186.9 KER24589.1 - 0.96 8.5 14.6 2.1 7.4 14.6 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_D PF01813.17 KER24590.1 - 0.013 15.3 5.1 0.013 15.3 5.1 1.0 1 0 0 1 1 1 0 ATP synthase subunit D DUF5595 PF18077.1 KER24590.1 - 0.021 14.9 2.8 0.032 14.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF5320 PF17253.2 KER24590.1 - 0.07 14.2 0.4 0.088 13.9 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Pro_isomerase PF00160.21 KER24591.1 - 6.4e-52 176.0 0.0 8.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NHL PF01436.21 KER24593.1 - 0.0029 17.5 0.1 5.4 7.3 0.0 4.6 5 0 0 5 5 5 1 NHL repeat Ank_2 PF12796.7 KER24595.1 - 8.2e-36 122.5 1.8 1.3e-08 35.3 0.0 5.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KER24595.1 - 2e-20 72.3 8.0 9.1e-05 22.7 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KER24595.1 - 4.8e-18 65.3 4.1 1.6e-05 25.4 0.0 7.0 2 1 6 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER24595.1 - 4e-15 54.4 9.4 0.0074 16.7 0.1 8.2 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KER24595.1 - 1.2e-11 44.6 4.5 0.0058 16.9 0.0 6.0 5 2 2 7 7 7 3 Ankyrin repeats (many copies) VWA_3 PF13768.6 KER24596.1 - 1.7e-21 76.8 0.0 4.1e-10 39.8 0.0 3.7 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA PF00092.28 KER24596.1 - 3.9e-06 27.2 0.0 0.067 13.4 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 KER24596.1 - 0.00033 21.3 0.1 0.34 11.6 0.0 3.4 4 0 0 4 4 4 2 von Willebrand factor type A domain DUF4537 PF15057.6 KER24597.1 - 8e-09 35.6 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Pyr_redox_dim PF02852.22 KER24598.1 - 0.075 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain tRNA-synt_1g PF09334.11 KER24600.1 - 7.8e-144 479.2 3.2 1.8e-112 375.9 0.3 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KER24600.1 - 5.3e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 KER24600.1 - 1.1e-05 23.9 0.0 0.018 13.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) zf-C2HC5 PF06221.13 KER24600.1 - 2.1 8.4 8.8 10 6.2 0.7 3.4 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zinc-ribbons_6 PF07191.12 KER24600.1 - 2.7 8.0 9.2 24 5.0 0.5 2.5 1 1 1 2 2 2 0 zinc-ribbons Homeodomain PF00046.29 KER24601.1 - 3e-16 59.0 3.2 4.8e-16 58.3 3.2 1.3 1 0 0 1 1 1 1 Homeodomain La PF05383.17 KER24603.1 - 1.7e-13 50.4 0.0 4.5e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KER24603.1 - 8.6e-10 38.3 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER24603.1 - 0.051 13.6 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 KER24604.1 - 3.7e-07 29.9 0.0 3.4e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP3D1 PF06375.11 KER24604.1 - 9.2 6.5 12.0 19 5.5 0.1 2.3 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 GalP_UDP_transf PF01087.22 KER24605.1 - 3e-57 194.0 0.0 4.5e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KER24605.1 - 9.2e-49 165.4 0.0 1.4e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KER24605.1 - 0.15 12.8 0.0 0.61 10.9 0.0 1.9 2 0 0 2 2 2 0 HIT domain Pkinase PF00069.25 KER24606.1 - 1.9e-19 70.1 0.0 2.9e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24606.1 - 2.6e-10 40.0 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER24606.1 - 1.3e-08 34.1 0.7 2.4e-08 33.2 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KER24606.1 - 1e-06 28.9 2.9 0.025 14.5 0.0 3.0 3 1 0 4 4 4 2 Phosphotransferase enzyme family SHIPPO-rpt PF07004.12 KER24607.1 - 0.00012 22.8 31.0 6.1 7.9 5.1 8.4 8 1 0 8 8 8 4 Sperm-tail PG-rich repeat Ig_3 PF13927.6 KER24608.1 - 2.7e-17 63.1 1.4 2.9e-14 53.4 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 KER24608.1 - 7.8e-14 51.5 0.1 4.6e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER24608.1 - 5.6e-10 39.4 0.0 5.6e-10 39.4 0.0 3.5 3 2 0 3 3 3 1 Immunoglobulin domain ig PF00047.25 KER24608.1 - 4.4e-07 30.0 0.5 3.6e-06 27.1 0.0 2.8 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.17 KER24608.1 - 0.0016 18.6 1.9 1.8 8.7 0.1 3.8 3 1 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER24608.1 - 0.031 14.3 0.7 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain UPA PF17217.3 KER24609.1 - 4.9e-10 39.5 0.0 1.7e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 UPA domain UPA PF17217.3 KER24611.1 - 5.1e-31 107.5 0.0 1.4e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KER24611.1 - 4.9e-27 94.1 0.1 1e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 KER24611.1 - 2.1e-13 50.7 0.4 1.3e-12 48.1 0.0 2.7 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 KER24611.1 - 3.9e-11 42.9 0.0 8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KER24611.1 - 2.3e-09 37.3 0.0 1.1e-08 35.1 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER24611.1 - 5.6e-09 36.2 0.0 3.3e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 KER24611.1 - 0.00048 20.2 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KER24611.1 - 0.0025 18.0 0.6 3.1 8.0 0.1 3.6 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KER24611.1 - 0.083 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain Inv-AAD PF18785.1 KER24611.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Thioredoxin PF00085.20 KER24612.1 - 2.9e-27 94.7 0.5 3.3e-27 94.5 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KER24612.1 - 5.6e-08 33.0 0.0 1.4e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KER24612.1 - 2.1e-07 30.9 0.1 2.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 KER24612.1 - 1.2e-06 28.9 0.0 4.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KER24612.1 - 6.9e-05 23.0 0.0 9.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KER24612.1 - 0.001 18.9 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KER24612.1 - 0.0012 18.6 0.1 0.0023 17.6 0.1 1.5 1 1 0 1 1 1 1 Redoxin DIM1 PF02966.16 KER24612.1 - 0.0052 16.6 0.1 0.0056 16.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.16 KER24612.1 - 0.02 13.9 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin TraF PF13728.6 KER24612.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.20 KER24613.1 - 3.4e-09 36.6 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KER24613.1 - 0.015 15.8 0.0 0.078 13.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain OST3_OST6 PF04756.13 KER24613.1 - 0.098 12.0 0.1 0.14 11.5 0.1 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KER24614.1 - 1e-22 80.1 0.0 1.2e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KER24614.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin-like Phosducin PF02114.16 KER24614.1 - 0.0009 18.3 0.0 0.00097 18.2 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 KER24614.1 - 0.0017 18.2 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KER24614.1 - 0.0068 16.6 0.1 0.02 15.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KER24614.1 - 0.0074 16.7 0.1 0.063 13.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KER24614.1 - 0.026 13.9 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 KER24614.1 - 0.039 13.8 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.16 KER24614.1 - 0.076 12.8 0.1 0.082 12.7 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 PAE PF03283.13 KER24616.1 - 2.3e-17 63.2 0.4 3.7e-17 62.5 0.4 1.2 1 0 0 1 1 1 1 Pectinacetylesterase Inhibitor_I36 PF03995.13 KER24617.1 - 0.073 13.0 9.3 0.96 9.4 1.2 2.4 1 1 1 2 2 2 0 Peptidase inhibitor family I36 LupA PF18242.1 KER24617.1 - 0.34 10.6 3.0 12 5.5 0.2 2.3 2 0 0 2 2 2 0 Legionella ubiquitin-specific protease A domain SapA PF02199.15 KER24617.1 - 2.3 8.6 13.1 8.5 6.8 2.8 2.6 2 0 0 2 2 2 0 Saposin A-type domain zf-CCCH_2 PF14608.6 KER24617.1 - 7.8 7.1 19.3 21 5.8 5.7 3.3 2 2 0 2 2 2 0 RNA-binding, Nab2-type zinc finger EF-hand_1 PF00036.32 KER24618.1 - 2.9e-31 104.7 6.4 2.5e-05 23.5 0.0 6.4 6 0 0 6 6 6 6 EF hand EF-hand_5 PF13202.6 KER24618.1 - 2.8e-28 96.1 11.1 4.7e-05 22.7 0.0 6.5 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 KER24618.1 - 3.1e-28 95.3 5.5 0.00032 20.4 0.1 6.2 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 KER24618.1 - 2.1e-25 89.0 6.9 1.4e-08 35.1 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KER24618.1 - 6.1e-14 51.6 8.4 0.025 14.4 0.0 6.1 3 1 3 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER24618.1 - 4.2e-10 39.9 4.5 0.031 14.6 1.0 3.6 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER24618.1 - 0.00049 20.4 0.2 2 8.8 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain VasL PF12486.8 KER24618.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL EF-hand_10 PF14788.6 KER24618.1 - 0.073 12.9 1.7 25 4.8 0.0 4.0 4 1 1 5 5 5 0 EF hand MutS_V PF00488.21 KER24621.1 - 2.3e-16 60.4 0.6 2.9e-16 60.1 0.6 1.1 1 0 0 1 1 1 1 MutS domain V zf-LYAR PF08790.11 KER24621.1 - 0.32 11.0 4.2 0.67 9.9 0.8 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Pkinase PF00069.25 KER24622.1 - 4.7e-46 157.3 0.0 6.3e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24622.1 - 2.5e-17 63.0 0.0 3.6e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER24622.1 - 0.00045 19.6 0.1 0.0015 17.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5352 PF17303.2 KER24622.1 - 0.11 12.3 0.4 17 5.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5352) IPP-2 PF04979.14 KER24623.1 - 1.3e-26 93.9 0.9 2.2e-26 93.2 0.2 1.7 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) UCH PF00443.29 KER24625.1 - 5.2e-44 150.7 0.0 7.7e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER24625.1 - 9.9e-17 61.5 0.4 1.4e-16 61.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KER24625.1 - 5.7e-06 26.0 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Trypan_PARP PF05887.11 KER24626.1 - 5.2 7.1 14.0 5.8 6.9 14.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_DNAp_acc PF04929.12 KER24626.1 - 7.3 5.4 6.5 8.3 5.3 6.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pkinase PF00069.25 KER24628.1 - 0.0011 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24628.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase TruB_C_2 PF16198.5 KER24631.1 - 1.3e-23 82.9 0.6 2.5e-23 82.0 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KER24631.1 - 1.5e-22 80.6 0.0 2.3e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.12 KER24631.1 - 6e-21 74.3 0.2 1.6e-20 72.9 0.2 1.8 1 0 0 1 1 1 1 DKCLD (NUC011) domain PUA PF01472.20 KER24631.1 - 1.2e-19 70.0 0.3 2.9e-19 68.8 0.3 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KER24631.1 - 0.027 14.7 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 UPF0113 PUA domain LRR_4 PF12799.7 KER24632.1 - 0.00058 20.2 5.2 0.0037 17.6 1.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER24632.1 - 0.16 11.8 9.2 0.12 12.1 6.5 2.3 2 0 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 KER24632.1 - 0.89 9.8 3.4 23 5.3 0.3 2.9 2 0 0 2 2 2 0 Leucine Rich repeat Ribosomal_S24e PF01282.19 KER24634.1 - 4.3e-31 106.7 0.0 8e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e zf-C2H2_3rep PF18868.1 KER24635.1 - 0.049 14.3 0.2 0.061 14.0 0.2 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats SRP54 PF00448.22 KER24637.1 - 3.3e-76 255.3 0.1 5.5e-76 254.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KER24637.1 - 2.1e-24 86.0 3.1 5.1e-24 84.8 0.1 2.9 1 1 2 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 KER24637.1 - 9e-18 64.3 1.3 9e-18 64.3 1.3 2.0 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KER24637.1 - 2.1e-06 27.5 0.4 1.3e-05 24.9 0.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 KER24637.1 - 2.8e-05 24.2 0.0 7.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KER24637.1 - 5.1e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER24637.1 - 0.00015 22.2 0.0 0.0015 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KER24637.1 - 0.00067 20.1 0.5 0.25 11.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KER24637.1 - 0.0009 18.7 0.5 0.77 9.2 0.1 2.8 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KER24637.1 - 0.0021 18.4 1.6 0.039 14.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KER24637.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KER24637.1 - 0.0031 16.8 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2209 PF09974.9 KER24637.1 - 0.0031 17.8 0.3 0.0078 16.6 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_5 PF07728.14 KER24637.1 - 0.0036 17.3 0.0 0.0095 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KER24637.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KER24637.1 - 0.0062 16.6 0.2 0.041 14.0 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KER24637.1 - 0.0086 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ResIII PF04851.15 KER24637.1 - 0.0098 15.9 0.5 0.025 14.6 0.4 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 KER24637.1 - 0.014 15.9 0.5 0.095 13.1 0.5 2.3 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KER24637.1 - 0.014 15.2 0.2 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 KER24637.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER24637.1 - 0.016 15.8 0.0 0.041 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain LpxB PF02684.15 KER24637.1 - 0.021 13.7 0.1 0.036 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase G-alpha PF00503.20 KER24637.1 - 0.036 13.2 0.2 0.39 9.8 0.0 2.2 2 1 1 3 3 3 0 G-protein alpha subunit AAA_31 PF13614.6 KER24637.1 - 0.049 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KER24637.1 - 0.057 13.1 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 KER24637.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.6 KER24637.1 - 0.07 12.7 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KER24637.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KER24637.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KER24637.1 - 0.084 12.8 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 KER24637.1 - 0.09 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 KER24637.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 KER24637.1 - 0.11 12.3 0.0 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TAP42 PF04177.12 KER24638.1 - 2.1e-61 207.8 0.0 3.8e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 TAP42-like family DUF4604 PF15377.6 KER24638.1 - 3.1e-13 50.5 6.0 3.1e-13 50.5 6.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) SHIPPO-rpt PF07004.12 KER24641.1 - 6.9e-11 42.5 26.8 0.058 14.3 0.0 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Ras PF00071.22 KER24642.1 - 9.4e-25 87.1 0.3 1.6e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER24642.1 - 1.3e-05 25.4 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KER24642.1 - 0.023 14.2 0.3 0.036 13.6 0.3 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KER24642.1 - 0.049 13.7 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Phospho_p8 PF10195.9 KER24642.1 - 0.12 12.9 1.7 0.36 11.4 1.7 1.9 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 SET PF00856.28 KER24643.1 - 9.4e-09 35.9 0.0 2.9e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 SET domain Fer4_11 PF13247.6 KER24643.1 - 0.051 13.7 0.7 0.051 13.7 0.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer2 PF00111.27 KER24644.1 - 2.4e-10 40.2 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ISP3_C PF18045.1 KER24644.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 ISP3 C-terminal tRNA-synt_2d PF01409.20 KER24646.1 - 4.4e-49 167.2 0.7 4.4e-29 101.7 0.1 3.0 3 1 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KER24646.1 - 1.6e-17 63.7 0.0 6.6e-17 61.7 0.0 2.1 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain ETC_C1_NDUFA5 PF04716.14 KER24646.1 - 0.1 12.4 0.0 24 4.8 0.0 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region Ets PF00178.22 KER24647.1 - 1.6e-34 118.2 0.3 3.1e-34 117.3 0.3 1.5 1 0 0 1 1 1 1 Ets-domain UPAR_LY6_2 PF16975.5 KER24647.1 - 0.0064 16.7 0.3 0.016 15.4 0.3 1.6 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Forkhead PF00250.18 KER24649.1 - 1.6e-25 89.1 0.3 3.4e-25 88.1 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain Galactosyl_T PF01762.21 KER24651.1 - 5.9e-15 55.6 0.0 1.1e-13 51.5 0.0 2.1 2 0 0 2 2 2 1 Galactosyltransferase DUF3677 PF12432.8 KER24651.1 - 0.13 12.6 0.2 0.34 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) G-alpha PF00503.20 KER24652.1 - 9.8e-124 413.1 6.2 1.3e-123 412.7 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER24652.1 - 1.4e-17 63.7 2.9 2.2e-13 50.1 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER24652.1 - 6.1e-06 25.8 4.3 0.00047 19.6 1.7 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KER24652.1 - 0.00024 21.3 3.1 0.18 12.0 0.4 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER24652.1 - 0.0056 16.3 2.1 0.23 11.0 0.5 2.4 2 0 0 2 2 2 1 Ras family TniB PF05621.11 KER24652.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KER24652.1 - 0.071 12.9 0.3 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KER24652.1 - 0.18 11.1 0.2 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ribosomal_S13_N PF08069.12 KER24653.1 - 4.1e-31 106.8 0.8 9.9e-31 105.6 0.8 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KER24653.1 - 3.9e-14 52.6 0.2 5.8e-14 52.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KER24653.1 - 0.12 12.3 0.0 0.44 10.5 0.0 1.8 1 1 0 2 2 2 0 'Paired box' domain Cadherin PF00028.17 KER24654.1 - 6e-32 109.9 0.0 6.9e-14 52.1 0.0 3.3 2 1 1 3 3 3 3 Cadherin domain Cadherin_pro PF08758.11 KER24654.1 - 0.084 13.1 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Cadherin prodomain like Shisa PF13908.6 KER24654.1 - 0.18 12.1 0.2 0.26 11.5 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PA PF02225.22 KER24655.1 - 1.5e-09 37.7 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 PA domain MAS20 PF02064.15 KER24658.1 - 5.9e-35 120.2 0.6 2.3e-34 118.3 0.6 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor DUF3188 PF11384.8 KER24658.1 - 0.15 11.7 0.3 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) MFS_1 PF07690.16 KER24660.1 - 3.3e-22 78.9 43.4 1e-17 64.2 10.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 KER24660.1 - 3.9 7.2 0.0 3.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 KER24661.1 - 5e-05 22.4 0.2 0.16 10.9 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CDI PF02234.19 KER24661.1 - 0.15 12.3 0.4 0.29 11.4 0.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor VHS PF00790.19 KER24663.1 - 2e-28 99.0 0.0 4.6e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KER24663.1 - 1.1e-09 38.4 0.1 4.1e-09 36.6 0.1 2.1 2 0 0 2 2 2 1 GAT domain ETC_C1_NDUFA4 PF04800.12 KER24664.1 - 3.8e-37 126.4 0.0 5.4e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region PH PF00169.29 KER24665.1 - 2.3e-12 47.3 0.2 5.2e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 PH domain PDZ_6 PF17820.1 KER24665.1 - 4.3e-07 29.7 0.0 9.7e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.30 KER24665.1 - 1.6e-06 28.5 0.0 3.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ PF00595.24 KER24665.1 - 3e-06 27.5 0.0 5.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SAM_2 PF07647.17 KER24665.1 - 4.1e-06 26.8 0.0 7.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CRIC_ras_sig PF10534.9 KER24665.1 - 1.2e-05 25.4 0.1 8.2e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Connector enhancer of kinase suppressor of ras PDZ_2 PF13180.6 KER24665.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF4020 PF13212.6 KER24665.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) PH_11 PF15413.6 KER24665.1 - 0.92 10.0 5.6 9.8 6.7 5.6 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain CH PF00307.31 KER24666.1 - 1.3e-13 51.0 0.0 3.2e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER24666.1 - 3.4e-06 26.8 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Borrelia_P83 PF05262.11 KER24666.1 - 0.0059 15.2 0.5 0.0059 15.2 0.5 1.7 2 0 0 2 2 2 1 Borrelia P83/100 protein ERM PF00769.19 KER24666.1 - 0.0062 16.4 0.6 0.0062 16.4 0.6 4.5 2 1 1 3 3 3 1 Ezrin/radixin/moesin family ADIP PF11559.8 KER24666.1 - 0.0075 16.4 2.0 0.0075 16.4 2.0 5.3 5 1 0 5 5 5 1 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.11 KER24666.1 - 0.011 15.6 1.0 0.011 15.6 1.0 4.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.12 KER24666.1 - 0.017 15.6 8.7 2.4 8.7 0.1 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.9 KER24666.1 - 0.66 10.3 25.1 0.037 14.3 4.9 4.4 3 2 0 3 3 3 0 Zinc finger-containing protein DUF4817 PF16087.5 KER24667.1 - 2.8e-09 36.7 0.0 7.5e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 KER24667.1 - 0.0091 15.8 0.5 0.026 14.3 0.1 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_17 PF12728.7 KER24667.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KER24667.1 - 0.14 12.0 0.1 3.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DnaJ_C PF01556.18 KER24668.1 - 8.8e-42 142.7 0.4 1.2e-41 142.3 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KER24668.1 - 2.3e-28 98.1 6.1 4.8e-28 97.1 5.9 1.6 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 KER24668.1 - 0.014 15.3 0.3 0.028 14.4 0.3 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DNase-RNase PF02577.14 KER24668.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Bifunctional nuclease E1_dh PF00676.20 KER24669.1 - 3.6e-111 370.9 0.0 4.2e-111 370.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KER24669.1 - 0.0077 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Neur_chan_LBD PF02931.23 KER24670.1 - 1.2e-57 194.9 0.5 1.8e-57 194.2 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER24670.1 - 8.7e-28 98.0 0.0 1.7e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RVT_1 PF00078.27 KER24670.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 KER24672.1 - 3.5e-07 30.2 0.1 9.2e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 KER24677.1 - 1.9e-33 116.0 0.0 3.5e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24677.1 - 1.3e-12 47.5 0.0 3.3e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER24677.1 - 0.00023 20.6 0.0 0.00089 18.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER24677.1 - 0.014 15.0 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KER24677.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Beta-lactamase PF00144.24 KER24678.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase Lig_chan-Glu_bd PF10613.9 KER24679.1 - 2.5e-16 59.9 0.0 4.3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 KER24679.1 - 9.2e-16 58.0 0.0 2.3e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 KER24679.1 - 1.3e-10 41.1 0.0 4.3e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Flg_bbr_C PF06429.13 KER24679.1 - 0.16 12.1 0.8 0.35 11.0 0.2 1.8 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal Lig_chan PF00060.26 KER24683.1 - 9.8e-13 48.2 0.5 2.2e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Ligand-gated ion channel SBP_bac_3 PF00497.20 KER24683.1 - 3.4e-07 29.9 0.0 5.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KER24683.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site PHD_2 PF13831.6 KER24684.1 - 9.3e-06 25.1 6.0 9.3e-06 25.1 6.0 2.0 2 0 0 2 2 2 1 PHD-finger MBT PF02820.18 KER24684.1 - 0.0035 17.7 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 KER24684.1 - 0.029 14.3 3.8 3.2 7.7 0.3 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.26 KER24684.1 - 0.042 14.3 0.8 0.14 12.6 0.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Agenet PF05641.12 KER24684.1 - 0.053 14.0 0.8 0.47 11.0 0.2 2.4 2 0 0 2 2 2 0 Agenet domain PHD PF00628.29 KER24684.1 - 0.14 12.1 17.2 0.055 13.4 13.9 2.2 2 1 0 2 2 2 0 PHD-finger zf-NPL4 PF05020.15 KER24686.1 - 1.4e-33 116.1 0.0 1.9e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region NPL4 PF05021.15 KER24686.1 - 8.2e-30 104.2 0.0 1.5e-18 67.2 0.0 2.1 1 1 1 2 2 2 2 NPL4 family LisH PF08513.11 KER24687.1 - 0.014 15.3 0.4 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 LisH RRM_1 PF00076.22 KER24689.1 - 4.2e-10 39.3 0.0 6.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER24689.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 KER24690.1 - 1.8e-54 182.3 0.7 2.2e-19 69.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER24690.1 - 7.3e-48 160.4 1.3 6.2e-11 42.6 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER24690.1 - 2.4e-36 123.3 1.3 3.6e-09 36.7 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KER24690.1 - 2.1e-31 107.0 0.4 1.2e-05 25.5 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KER24690.1 - 5.5e-31 103.1 0.0 2.7e-05 24.2 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat ScdA_N PF04405.14 KER24690.1 - 0.045 13.4 0.1 12 5.6 0.0 3.8 5 0 0 5 5 5 0 Domain of Unknown function (DUF542) HMA PF00403.26 KER24695.1 - 0.0012 19.2 0.1 0.0023 18.3 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Drf_GBD PF06371.13 KER24695.1 - 0.055 13.0 0.1 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Arm PF00514.23 KER24695.1 - 0.088 12.9 0.7 0.21 11.7 0.7 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KER24695.1 - 0.12 12.7 0.4 0.57 10.6 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat 2Fe-2S_thioredx PF01257.19 KER24696.1 - 3.3e-61 205.4 0.0 4.2e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Ank_2 PF12796.7 KER24698.1 - 7.8e-07 29.6 6.2 0.00045 20.8 1.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER24698.1 - 1.2e-06 29.0 3.9 0.00074 20.0 0.3 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER24698.1 - 4.1e-06 26.7 5.2 0.055 14.0 0.6 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KER24698.1 - 0.00041 20.6 0.5 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KER24698.1 - 0.057 13.9 8.4 3.4 8.3 0.1 3.4 3 1 0 3 3 3 0 Ankyrin repeat SapB_1 PF05184.15 KER24698.1 - 0.07 13.2 0.5 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 Pkinase PF00069.25 KER24699.1 - 1.5e-27 96.6 0.0 6.9e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24699.1 - 9.1e-26 90.7 0.0 1.5e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 KER24699.1 - 1.3e-17 63.3 27.7 0.0057 16.4 0.3 8.7 6 2 2 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KER24699.1 - 3e-16 59.3 28.6 2.8e-05 24.4 0.1 9.2 9 1 0 9 9 8 3 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 KER24699.1 - 2.2e-13 50.6 0.0 0.12 13.0 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER24699.1 - 1.3e-12 46.7 1.9 0.078 13.6 0.0 6.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KER24699.1 - 7.1e-12 45.6 3.5 0.33 11.6 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER24699.1 - 3.2e-11 43.2 0.9 0.029 14.7 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) COR PF16095.5 KER24699.1 - 2e-07 31.0 0.1 6.2e-06 26.2 0.0 2.8 2 1 0 2 2 2 1 C-terminal of Roc, COR, domain Ank PF00023.30 KER24699.1 - 1.7e-06 28.2 3.8 0.28 11.7 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Roc PF08477.13 KER24699.1 - 0.00024 21.3 0.2 0.43 10.8 0.0 3.1 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KER24699.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KER24699.1 - 0.025 14.2 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Ras family LRR_6 PF13516.6 KER24699.1 - 0.048 13.7 23.5 0.76 10.0 0.1 8.0 8 0 0 8 8 8 0 Leucine Rich repeat ABC_tran PF00005.27 KER24699.1 - 0.067 13.7 0.0 0.24 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter LRR_8 PF13855.6 KER24700.1 - 2e-08 33.8 4.9 1.5e-05 24.7 1.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat COR PF16095.5 KER24700.1 - 7.4e-08 32.4 0.0 3.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 KER24700.1 - 1e-05 25.7 7.0 0.0014 18.9 1.3 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Roc PF08477.13 KER24700.1 - 1.4e-05 25.3 0.2 0.14 12.4 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER24700.1 - 0.0035 17.0 0.0 0.088 12.4 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KER24700.1 - 0.0035 17.7 0.0 0.0099 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KER24700.1 - 0.044 14.3 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KER24700.1 - 0.17 11.6 0.0 0.47 10.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain LRR_1 PF00560.33 KER24700.1 - 0.3 11.8 7.4 7 7.6 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Kelch_6 PF13964.6 KER24703.1 - 7e-14 51.5 4.2 0.02 15.2 0.1 7.0 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KER24703.1 - 6.6e-11 42.0 7.8 0.24 11.4 0.0 6.3 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KER24703.1 - 6e-09 35.8 2.6 0.13 12.3 0.0 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KER24703.1 - 2.6e-06 27.2 5.9 4.6 7.4 0.0 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KER24703.1 - 6.5e-05 23.1 13.5 1.3 9.4 1.1 6.8 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KER24703.1 - 8.4e-05 22.1 2.8 3.2 7.4 0.4 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KER24704.1 - 1.5e-60 200.6 9.6 1.1e-14 53.7 0.5 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KER24704.1 - 1.1e-40 136.6 5.1 1.8e-07 31.2 0.0 6.8 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KER24704.1 - 3.3e-26 90.2 9.4 3.3e-06 26.9 0.0 7.3 5 1 1 6 6 6 5 Kelch motif BTB PF00651.31 KER24704.1 - 7e-25 87.4 0.1 7.1e-23 81.0 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KER24704.1 - 1.9e-22 79.0 5.6 8.2e-05 22.5 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 KER24704.1 - 2.5e-15 56.4 0.1 4.2e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 KER24704.1 - 1.7e-14 53.7 2.5 0.0033 17.7 0.2 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KER24704.1 - 2e-07 30.8 5.3 1.2 9.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif DUF3342 PF11822.8 KER24704.1 - 8.2e-05 22.7 0.0 0.0079 16.4 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3342) Rab_bind PF16704.5 KER24704.1 - 0.19 11.8 0.5 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Rab binding domain QVR PF17064.5 KER24705.1 - 0.0082 16.4 5.3 0.018 15.3 5.3 1.6 1 0 0 1 1 1 1 Sleepless protein RRM_1 PF00076.22 KER24707.1 - 7.3e-25 86.6 0.0 3.5e-13 49.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KER24707.1 - 0.014 15.6 0.0 17 5.6 0.0 3.2 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter NosL PF05573.12 KER24707.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 NosL RVT_1 PF00078.27 KER24710.1 - 0.0032 17.0 0.0 0.0084 15.6 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nitr_red_bet_C PF14711.6 KER24711.1 - 0.14 11.9 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal HAT_KAT11 PF08214.11 KER24712.1 - 5.4e-65 220.0 0.0 1.2e-64 218.9 0.0 1.6 1 0 0 1 1 1 1 Histone acetylation protein zf-TAZ PF02135.16 KER24712.1 - 1.8e-25 89.2 65.4 5.3e-18 65.3 17.1 4.0 3 0 0 3 3 3 2 TAZ zinc finger KIX PF02172.16 KER24712.1 - 1.2e-24 86.3 0.3 1.2e-24 86.3 0.3 2.0 2 0 0 2 2 2 1 KIX domain Bromodomain PF00439.25 KER24712.1 - 6.4e-21 74.2 3.6 1.4e-20 73.2 0.5 2.6 2 0 0 2 2 2 1 Bromodomain DUF902 PF06001.13 KER24712.1 - 6.6e-17 61.7 5.0 1.4e-16 60.7 5.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) ZZ PF00569.17 KER24712.1 - 5.1e-12 45.4 8.8 5.1e-12 45.4 8.8 3.8 4 0 0 4 4 4 1 Zinc finger, ZZ type SRP-alpha_N PF04086.13 KER24712.1 - 0.00071 19.6 0.5 0.00071 19.6 0.5 3.0 3 0 0 3 3 3 1 Signal recognition particle, alpha subunit, N-terminal KIX_2 PF16987.5 KER24712.1 - 0.0063 16.5 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 KIX domain TrwC PF08751.11 KER24713.1 - 0.002 17.7 0.1 0.002 17.7 0.1 1.0 1 0 0 1 1 1 1 TrwC relaxase S1 PF00575.23 KER24715.1 - 1.7e-13 50.7 0.2 0.00017 21.9 0.0 6.9 8 0 0 8 8 8 3 S1 RNA binding domain TPR_14 PF13428.6 KER24715.1 - 4.2e-06 27.1 0.9 0.45 11.5 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER24715.1 - 1.2e-05 25.9 2.3 0.00022 21.8 0.7 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER24715.1 - 0.032 14.7 0.1 4.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_US9 PF06072.11 KER24716.1 - 0.0096 15.8 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 Peptidase_M14 PF00246.24 KER24717.1 - 1.6e-15 57.7 0.0 3.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KER24717.1 - 4.2e-09 36.7 1.5 3.4e-08 33.8 0.2 2.5 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain zf-C3HC4_2 PF13923.6 KER24718.1 - 6.1e-06 26.0 17.5 0.00039 20.2 12.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER24718.1 - 1.1e-05 25.3 20.8 4.8e-05 23.3 11.8 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KER24718.1 - 0.00017 21.8 20.8 0.0074 16.6 13.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KER24718.1 - 0.00029 20.6 14.8 0.018 14.9 10.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER24718.1 - 0.00081 19.2 21.3 0.0041 17.0 12.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Peptidase_S7 PF00949.21 KER24718.1 - 0.048 13.5 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease zf-C3HC4_4 PF15227.6 KER24718.1 - 0.18 12.0 16.1 1.4 9.2 11.5 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KER24718.1 - 3.2 7.8 20.3 80 3.3 0.8 3.0 1 1 2 3 3 3 0 zinc-RING finger domain Sod_Cu PF00080.20 KER24720.1 - 8.3e-12 45.5 0.6 4.7e-11 43.0 0.5 1.8 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 KER24721.1 - 8.2e-38 129.8 1.2 9.7e-38 129.5 1.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 KER24722.1 - 6.8e-30 104.1 0.1 8.5e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 KER24723.1 - 6.7e-29 100.9 0.1 8.2e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-C2H2 PF00096.26 KER24725.1 - 7.8e-17 60.7 26.6 0.00053 20.3 0.8 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER24725.1 - 1.4e-12 47.4 29.2 2.3e-07 30.9 0.4 6.0 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER24725.1 - 1.2e-06 28.9 23.2 0.0089 16.8 0.6 6.6 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 KER24725.1 - 0.00011 22.7 23.1 0.00055 20.5 1.7 5.3 4 2 1 5 5 5 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KER24725.1 - 0.028 14.6 10.1 0.55 10.4 0.2 3.9 2 1 1 3 3 3 0 Aberrant zinc-finger zf_ZIC PF18366.1 KER24725.1 - 0.23 11.6 3.7 0.34 11.0 0.0 3.1 3 0 0 3 3 3 0 Zic proteins zinc finger domain DUF629 PF04780.12 KER24725.1 - 8.8 4.7 7.9 12 4.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) WAC_Acf1_DNA_bd PF10537.9 KER24728.1 - 1.7e-24 86.2 0.0 5.4e-24 84.6 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 KER24728.1 - 2.1e-23 81.9 17.5 1.6e-13 50.3 3.4 2.8 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 KER24728.1 - 7.7e-17 61.6 1.4 4.1e-16 59.3 0.1 3.1 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bromodomain PF00439.25 KER24728.1 - 3.9e-15 55.7 0.0 1.1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KER24728.1 - 1.3e-05 24.6 8.7 0.031 13.8 0.4 3.1 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 KER24728.1 - 0.00094 19.4 6.9 0.29 11.4 0.5 2.7 2 0 0 2 2 2 2 PHD-like zinc-binding domain Zf_RING PF16744.5 KER24728.1 - 0.0041 17.2 8.8 0.4 10.8 1.0 3.1 2 0 0 2 2 2 2 KIAA1045 RING finger zf-RING_2 PF13639.6 KER24728.1 - 0.0078 16.5 25.1 0.017 15.4 6.8 2.8 2 0 0 2 2 2 1 Ring finger domain zf-PHD-like PF15446.6 KER24728.1 - 0.016 14.8 11.2 0.15 11.7 0.6 4.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Pox_D5 PF03288.16 KER24728.1 - 0.035 14.6 0.7 0.81 10.2 0.6 2.7 2 0 0 2 2 2 0 Poxvirus D5 protein-like zf-HC5HC2H_2 PF13832.6 KER24728.1 - 0.044 13.9 7.6 0.32 11.2 0.8 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 KER24728.1 - 0.095 12.6 16.3 1.3 9.0 1.9 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KER24728.1 - 0.33 10.9 14.2 0.027 14.4 2.6 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDT PF02791.17 KER24728.1 - 0.8 10.1 4.6 6 7.3 2.3 2.9 2 1 0 2 2 2 0 DDT domain zf-rbx1 PF12678.7 KER24728.1 - 4.2 7.7 16.5 0.6 10.4 5.5 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain Sedlin_N PF04628.13 KER24730.1 - 7e-42 142.7 0.1 7.9e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KER24730.1 - 2.6e-05 24.2 0.0 2.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family mRNA_decap_C PF16741.5 KER24730.1 - 0.11 11.8 0.3 0.43 9.9 0.3 2.0 1 1 0 1 1 1 0 mRNA-decapping enzyme C-terminus O_Spanin_T7 PF17531.2 KER24732.1 - 0.034 14.2 0.8 0.15 12.1 0.1 2.4 1 1 1 2 2 2 0 outer-membrane spanin sub-unit Peptidase_M14 PF00246.24 KER24734.1 - 3e-17 63.4 0.0 1.1e-16 61.5 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 KER24734.1 - 2.1e-11 44.1 3.6 2.4e-11 44.0 0.9 2.3 2 1 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 KER24734.1 - 0.00021 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PTEN_C2 PF10409.9 KER24736.1 - 4.7e-06 26.4 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 KER24736.1 - 7.3e-06 26.2 0.3 1.7e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KER24736.1 - 0.00055 20.0 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KER24736.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KER24736.1 - 0.053 13.3 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RrnaAD PF00398.20 KER24738.1 - 9.5e-25 87.1 0.0 1.2e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase IRS PF02174.17 KER24739.1 - 9.4e-11 41.5 0.0 2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) RVT_1 PF00078.27 KER24740.1 - 7.4e-32 110.7 0.0 3.7e-15 56.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KER24740.1 - 1.2e-17 63.9 4.6 6.1e-05 23.7 0.1 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF1016_N PF17761.1 KER24740.1 - 0.12 12.5 0.2 21 5.2 0.0 2.2 2 0 0 2 2 2 0 DUF1016 N-terminal domain DUF4675 PF15720.5 KER24741.1 - 0.032 14.0 0.7 0.43 10.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4675) DUF3446 PF11928.8 KER24741.1 - 0.57 10.5 12.2 2.3 8.6 1.2 2.2 1 1 1 2 2 2 0 Early growth response N-terminal domain CEP19 PF14933.6 KER24745.1 - 2e-25 90.0 1.2 2e-12 47.7 0.1 2.3 2 1 0 2 2 2 2 CEP19-like protein RTTN_N PF14726.6 KER24745.1 - 0.06 14.1 0.1 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning CSN8_PSD8_EIF3K PF10075.9 KER24748.1 - 1.6e-18 67.1 0.4 1.9e-18 66.8 0.4 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DEAD PF00270.29 KER24749.1 - 4.5e-31 108.0 0.0 9.7e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER24749.1 - 1.9e-22 79.7 0.0 1.7e-21 76.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NCD2 PF04905.13 KER24749.1 - 1.4e-21 76.8 0.2 9.4e-10 38.5 0.1 2.5 2 0 0 2 2 2 2 NAB conserved region 2 (NCD2) WD40 PF00400.32 KER24749.1 - 5.5e-06 27.0 0.1 0.77 10.7 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_8 PF13855.6 KER24749.1 - 5.9e-05 22.8 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat CMS1 PF14617.6 KER24749.1 - 0.0026 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KER24749.1 - 0.006 16.6 0.0 0.018 15.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_4 PF12799.7 KER24749.1 - 0.021 15.3 0.9 0.078 13.4 0.3 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DUF3038 PF11237.8 KER24751.1 - 0.79 9.7 6.1 0.13 12.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) AAA PF00004.29 KER24753.1 - 1.6e-11 44.8 0.0 3.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER24753.1 - 2.2e-05 24.5 0.0 4.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER24753.1 - 0.0002 21.6 0.0 0.0009 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER24753.1 - 0.00025 21.5 0.0 0.019 15.4 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KER24753.1 - 0.00027 21.1 0.0 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER24753.1 - 0.00035 20.4 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KER24753.1 - 0.00036 20.8 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KER24753.1 - 0.00098 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KER24753.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER24753.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_assoc_2 PF16193.5 KER24753.1 - 0.039 14.3 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA C-terminal domain Rad17 PF03215.15 KER24753.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KER24753.1 - 0.043 13.4 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KER24753.1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KER24753.1 - 0.047 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KER24753.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_8 PF12780.7 KER24753.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 DnaB_C PF03796.15 KER24753.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF1871 PF08958.10 KER24753.1 - 0.15 12.4 0.0 5.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) IQ PF00612.27 KER24755.1 - 0.024 14.4 1.5 0.061 13.1 1.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif WAK PF08488.11 KER24755.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Wall-associated kinase Rcd1 PF04078.13 KER24756.1 - 4.6e-26 91.7 2.9 2.3e-19 69.7 1.2 2.8 2 1 0 2 2 2 2 Cell differentiation family, Rcd1-like RBD-FIP PF09457.10 KER24756.1 - 0.073 13.0 0.1 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 FIP domain Hfq PF17209.3 KER24758.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Plexin_cytopl PF08337.12 KER24761.1 - 2e-122 409.7 1.2 1.4e-70 238.5 0.0 2.2 2 0 0 2 2 2 2 Plexin cytoplasmic RasGAP domain Sema PF01403.19 KER24761.1 - 1.7e-18 66.7 0.0 4.5e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 Sema domain PSI PF01437.25 KER24761.1 - 3.9e-14 52.9 41.5 2.7e-07 31.0 8.8 4.1 3 0 0 3 3 3 3 Plexin repeat TIG PF01833.24 KER24761.1 - 1.5e-11 44.2 0.0 0.0013 18.8 0.0 4.8 4 1 0 4 4 4 2 IPT/TIG domain Mod_r PF07200.13 KER24764.1 - 3.2e-10 40.3 1.3 3.5e-10 40.2 1.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FF PF01846.19 KER24765.1 - 8.3e-40 134.7 13.1 4.1e-09 36.5 0.6 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.26 KER24765.1 - 1.2e-18 66.9 17.1 1.3e-09 38.0 5.3 3.0 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 KER24765.1 - 0.036 14.4 6.2 1.6 9.1 1.4 3.0 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Clat_adaptor_s PF01217.20 KER24765.1 - 0.039 13.9 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Clathrin adaptor complex small chain WW_1 PF18507.1 KER24765.1 - 1 9.1 4.2 7 6.4 0.2 2.9 3 0 0 3 3 3 0 WW domain DHHC PF01529.20 KER24768.1 - 1e-33 116.3 16.2 1e-33 116.3 16.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM251 PF15190.6 KER24768.1 - 2.6 8.0 6.6 6.1 6.8 5.3 2.2 1 1 1 2 2 2 0 Transmembrane protein 251 EpsG PF14897.6 KER24768.1 - 4.4 6.5 20.9 0.32 10.3 7.3 2.1 2 0 0 2 2 2 0 EpsG family Myb_DNA-bind_5 PF13873.6 KER24770.1 - 1.1e-05 25.3 0.1 1.1e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KER24770.1 - 0.042 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-C4H2 PF10146.9 KER24770.1 - 7 6.9 6.4 3.4 7.9 0.2 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein Myb_DNA-bind_5 PF13873.6 KER24773.1 - 0.00017 21.6 0.1 0.00036 20.6 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KER24773.1 - 0.0022 18.4 0.1 0.0046 17.3 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SSTK-IP PF15836.5 KER24773.1 - 0.0049 17.0 2.0 0.063 13.4 0.1 2.5 2 0 0 2 2 2 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein DUF608 PF04685.13 KER24774.1 - 1.3e-133 445.7 0.6 1.7e-133 445.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 KER24774.1 - 1.1e-81 274.8 0.0 1.6e-81 274.2 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term RVT_1 PF00078.27 KER24776.1 - 1.8e-12 47.3 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Frataxin_Cyay PF01491.16 KER24777.1 - 2.8e-33 114.2 0.0 3.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DUF3450 PF11932.8 KER24778.1 - 0.018 14.3 13.0 0.094 12.0 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1043 PF06295.12 KER24778.1 - 0.064 13.3 13.4 0.42 10.6 2.3 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1043) T2SSF PF00482.23 KER24778.1 - 0.26 11.2 6.1 2.1 8.3 0.2 3.3 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F BAR_3_WASP_bdg PF10456.9 KER24778.1 - 0.34 10.4 2.5 1.3 8.5 0.8 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein dCache_3 PF14827.6 KER24778.1 - 5.8 6.5 11.7 6.7 6.3 2.5 2.6 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase ANAPC4_WD40 PF12894.7 KER24779.1 - 6.9e-20 71.1 0.0 2.7e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER24779.1 - 0.0001 23.0 0.5 0.016 16.0 0.1 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Tom37 PF10568.9 KER24782.1 - 5.6e-09 36.4 0.0 9.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KER24782.1 - 0.0013 18.5 0.0 0.0042 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KER24782.1 - 0.063 14.0 0.0 0.15 12.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Sulfotransfer_4 PF17784.1 KER24784.1 - 2e-66 223.9 0.0 7.2e-53 179.6 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER24784.1 - 0.0018 18.7 0.0 0.0037 17.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family B56 PF01603.20 KER24786.1 - 8.1e-50 170.0 4.6 9.9e-50 169.7 4.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF5617 PF18493.1 KER24786.1 - 0.035 14.2 0.2 0.074 13.2 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5617) Vps35 PF03635.17 KER24786.1 - 0.13 10.8 2.3 0.18 10.3 2.3 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 RhoGEF PF00621.20 KER24787.1 - 6.5e-21 75.4 0.4 1.3e-19 71.2 0.1 2.3 2 0 0 2 2 2 1 RhoGEF domain RVT_1 PF00078.27 KER24787.1 - 0.052 13.1 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Acyltransferase PF01553.21 KER24788.1 - 1.1e-25 89.8 0.0 1.7e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase LSDAT_euk PF18139.1 KER24789.1 - 2.9e-21 76.0 0.0 1.2e-20 74.0 0.0 1.9 2 0 0 2 2 2 1 SLOG in TRPM Ion_trans PF00520.31 KER24789.1 - 2.9e-20 72.5 19.8 4.6e-20 71.9 19.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 KER24789.1 - 1e-06 29.2 0.0 5e-06 27.0 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER24789.1 - 0.00011 22.4 0.2 0.00089 19.5 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) PKD_channel PF08016.12 KER24789.1 - 0.00044 19.1 18.9 0.00066 18.5 18.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel LSDAT_prok PF18171.1 KER24789.1 - 0.0014 17.9 0.0 0.0086 15.3 0.0 2.0 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ank PF00023.30 KER24789.1 - 0.012 16.1 8.9 0.029 14.8 0.1 4.5 5 0 0 5 5 5 0 Ankyrin repeat TPR_12 PF13424.6 KER24790.1 - 4.7e-44 148.6 14.3 8e-19 67.7 0.5 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KER24790.1 - 8.9e-44 146.2 9.4 1.3e-10 40.8 0.2 6.7 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KER24790.1 - 8.7e-23 78.6 14.0 2.8e-05 23.8 0.2 6.4 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KER24790.1 - 2.7e-19 68.1 20.4 2.6e-06 27.0 0.3 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KER24790.1 - 4.3e-14 51.4 20.1 0.0011 19.0 0.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KER24790.1 - 1.2e-10 40.7 14.0 0.023 14.9 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER24790.1 - 2.8e-10 40.6 6.0 0.0099 16.4 0.4 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER24790.1 - 1.7e-07 31.8 12.0 0.005 17.5 1.9 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KER24790.1 - 1.5e-06 27.8 10.6 1.5e-05 24.5 1.4 3.6 2 1 1 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 KER24790.1 - 3.5e-06 27.4 8.8 1.4 10.0 0.3 6.1 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER24790.1 - 1.7e-05 24.9 6.5 0.21 12.1 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KER24790.1 - 5.5e-05 23.4 0.1 5.1 8.0 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.20 KER24790.1 - 0.0029 17.8 1.0 3.3 8.1 0.0 4.3 6 0 0 6 6 5 1 PPR repeat ANAPC3 PF12895.7 KER24790.1 - 0.007 16.6 8.3 0.12 12.7 0.2 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.12 KER24790.1 - 0.038 14.0 0.2 6.2 6.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) RPN6_N PF18055.1 KER24790.1 - 0.31 11.4 4.9 5.4 7.4 0.4 3.8 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Anoctamin PF04547.12 KER24791.1 - 1.9e-160 534.6 16.3 2.3e-160 534.3 16.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 KER24791.1 - 1.8e-66 224.1 0.1 2.8e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Claudin_2 PF13903.6 KER24791.1 - 0.0087 15.8 1.7 0.01 15.6 0.1 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Carb_bind PF10645.9 KER24791.1 - 0.095 12.9 1.7 0.24 11.7 1.7 1.6 1 0 0 1 1 1 0 Carbohydrate binding DUF2207 PF09972.9 KER24791.1 - 2.8 6.6 12.2 0.52 9.0 0.3 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) ICA69 PF04629.14 KER24792.1 - 0.22 11.8 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain P53 PF00870.18 KER24793.1 - 2.9e-27 95.7 0.0 4.6e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 P53 DNA-binding domain Ribosomal_L20 PF00453.18 KER24794.1 - 1.1e-19 70.5 0.1 1.4e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Peptidase_C54 PF03416.19 KER24795.1 - 1.2e-82 277.5 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 KER24795.1 - 0.093 12.2 0.2 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Peptidase family C78 CRM1_C PF08767.11 KER24796.1 - 3.8e-115 384.4 5.5 3.8e-115 384.4 5.5 2.4 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KER24796.1 - 2.2e-37 128.4 15.4 2.5e-37 128.2 3.0 5.0 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KER24796.1 - 4.1e-34 116.0 1.7 1e-33 114.8 0.7 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KER24796.1 - 7.4e-31 106.0 0.5 1.7e-29 101.7 0.3 3.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KER24796.1 - 2.6e-17 62.0 5.3 3.5e-17 61.6 3.9 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KER24796.1 - 3.3e-11 42.9 0.1 1.4e-10 40.9 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain BID PF06393.11 KER24796.1 - 0.06 12.9 1.2 0.19 11.2 0.1 2.5 3 0 0 3 3 3 0 BH3 interacting domain (BID) RhoGEF PF00621.20 KER24796.1 - 0.26 11.5 8.2 0.44 10.8 0.3 3.8 4 0 0 4 4 4 0 RhoGEF domain Sterol-sensing PF12349.8 KER24799.1 - 3.6e-06 26.9 3.4 3.6e-06 26.9 3.4 4.0 5 0 0 5 5 5 1 Sterol-sensing domain of SREBP cleavage-activation BSD PF03909.17 KER24799.1 - 0.001 19.0 0.1 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 BSD domain Patched PF02460.18 KER24799.1 - 6.5 4.7 16.7 0.0026 15.9 3.8 1.9 2 1 0 2 2 2 0 Patched family GP67 PF17634.2 KER24800.1 - 0.0089 16.4 15.3 0.015 15.7 15.3 1.3 1 0 0 1 1 1 1 Gene product 67 ScsC_N PF18312.1 KER24800.1 - 0.039 13.8 0.3 0.078 12.8 0.3 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Galactosyl_T PF01762.21 KER24802.1 - 3.3e-08 33.6 0.3 0.00041 20.2 0.0 2.4 3 0 0 3 3 3 2 Galactosyltransferase Fringe PF02434.16 KER24802.1 - 3.8e-05 23.3 1.2 0.00048 19.7 1.2 2.0 1 1 0 1 1 1 1 Fringe-like ig PF00047.25 KER24803.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 KER24804.1 - 4.4e-41 139.4 15.8 2.6e-07 31.2 0.0 10.4 10 1 0 10 10 10 8 Immunoglobulin domain I-set PF07679.16 KER24804.1 - 9.6e-32 108.9 0.0 2e-07 31.0 0.0 8.0 8 0 0 8 8 8 5 Immunoglobulin I-set domain ig PF00047.25 KER24804.1 - 3.5e-24 84.8 0.2 0.00042 20.4 0.0 9.1 8 1 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 KER24804.1 - 8.2e-23 80.6 6.0 0.00017 21.8 0.0 9.9 10 0 0 10 10 10 7 Immunoglobulin domain V-set PF07686.17 KER24804.1 - 5.2e-15 55.6 4.3 0.00055 20.1 0.0 8.2 7 2 0 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER24804.1 - 6e-15 55.1 13.1 0.02 14.9 0.2 9.0 8 1 0 8 8 8 4 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KER24804.1 - 5.9e-07 29.7 1.7 1.9e-06 28.1 1.7 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER24804.1 - 0.0062 17.1 2.4 0.052 14.1 1.5 2.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Izumo-Ig PF16706.5 KER24804.1 - 0.1 12.6 0.0 3.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain DUF5093 PF17011.5 KER24805.1 - 0.034 14.4 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) CD36 PF01130.21 KER24807.1 - 2.4e-124 415.4 0.4 2.9e-124 415.2 0.4 1.0 1 0 0 1 1 1 1 CD36 family PorA PF11271.8 KER24807.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Porin PorA IgaA PF07095.11 KER24807.1 - 0.38 8.7 2.5 0.19 9.7 0.2 1.5 2 0 0 2 2 2 0 Intracellular growth attenuator protein IgaA ATP-gua_Ptrans PF00217.19 KER24810.1 - 1.3e-159 528.0 0.0 8.4e-80 267.2 0.0 2.1 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KER24810.1 - 7.6e-28 96.7 0.0 1.7e-13 50.8 0.0 2.5 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain CotJB PF12652.7 KER24810.1 - 0.022 15.0 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 CotJB protein Nup192 PF11894.8 KER24811.1 - 1.6e-106 357.2 0.0 6.7e-61 205.9 0.0 2.9 2 1 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nop PF01798.18 KER24813.1 - 1.6e-103 345.1 0.1 2.8e-71 239.7 0.0 2.2 2 0 0 2 2 2 2 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KER24813.1 - 2.2e-39 135.1 0.3 3.9e-39 134.3 0.3 1.3 1 0 0 1 1 1 1 Prp31 C terminal domain RVT_1 PF00078.27 KER24813.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp PF00026.23 KER24815.1 - 6.5e-53 180.2 0.0 7.6e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER24815.1 - 1.3e-06 28.7 0.0 6.7e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER24815.1 - 0.0024 18.4 0.0 0.039 14.6 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KER24815.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KER24815.1 - 0.066 13.8 0.1 3.2 8.4 0.0 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KER24816.1 - 5.8e-47 160.6 0.0 1.1e-22 80.9 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER24816.1 - 0.00015 22.0 0.0 0.046 14.0 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BRO1 PF03097.18 KER24819.1 - 9.1e-95 317.7 0.0 1.4e-94 317.1 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Y_phosphatase PF00102.27 KER24819.1 - 3.7e-32 111.8 0.5 9.2e-19 67.9 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase ALIX_LYPXL_bnd PF13949.6 KER24819.1 - 1.2e-28 100.2 8.9 1e-27 97.2 8.1 2.8 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Peptidase_C1 PF00112.23 KER24821.1 - 4.4e-51 174.0 0.4 7.8e-51 173.2 0.4 1.3 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER24821.1 - 0.067 12.0 0.4 0.092 11.5 0.4 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_C1 PF00112.23 KER24822.1 - 8.9e-31 107.7 0.0 9.1e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER24822.1 - 0.2 10.4 1.2 0.26 10.0 1.2 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_C1 PF00112.23 KER24823.1 - 2.7e-65 220.5 2.5 3.2e-65 220.3 2.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER24823.1 - 0.0038 16.1 2.6 0.2 10.4 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family 7tm_1 PF00001.21 KER24824.1 - 9.1e-11 41.6 1.2 1.5e-10 40.9 1.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER24824.1 - 5.8e-06 25.8 0.1 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.15 KER24824.1 - 0.00021 21.3 0.1 0.00041 20.4 0.1 1.4 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa Peptidase_C1 PF00112.23 KER24825.1 - 9.7e-51 172.9 1.1 1.4e-50 172.4 1.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease PAS_9 PF13426.7 KER24826.1 - 0.0012 19.1 0.0 0.0016 18.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain Ion_trans PF00520.31 KER24828.1 - 5.4e-27 94.6 9.5 7.6e-27 94.1 9.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER24828.1 - 1.3e-10 41.0 4.0 4e-10 39.5 3.9 1.9 1 1 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 KER24828.1 - 6.8e-10 38.9 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SAND PF01342.21 KER24828.1 - 0.08 12.7 0.3 12 5.7 0.0 3.1 3 0 0 3 3 3 0 SAND domain SH3_14 PF18343.1 KER24828.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Dda helicase SH3 domain IRK PF01007.20 KER24828.1 - 2.3 8.1 9.9 0.048 13.5 1.6 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain LapA_dom PF06305.11 KER24828.1 - 2.5 8.0 3.9 2.6 7.9 0.5 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Rootletin PF15035.6 KER24829.1 - 0.0019 18.2 0.6 0.0068 16.5 0.4 1.9 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 KER24829.1 - 0.097 10.6 0.1 0.14 10.1 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAXIP1_C PF15364.6 KER24830.1 - 7.8e-20 71.6 0.0 1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein UDPG_MGDP_dh_N PF03721.14 KER24831.1 - 1.3e-33 116.2 0.0 2.7e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KER24831.1 - 1.7e-30 105.5 0.0 1.2e-29 102.8 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KER24831.1 - 2.1e-30 104.8 0.0 4.2e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain ubiquitin PF00240.23 KER24832.1 - 0.00066 19.4 0.2 1 9.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family HLH PF00010.26 KER24832.1 - 0.0013 18.6 2.5 0.0028 17.6 2.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 KER24832.1 - 0.039 14.2 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain TraX PF05857.11 KER24832.1 - 0.043 13.9 4.1 0.084 12.9 4.1 1.4 1 0 0 1 1 1 0 TraX protein PAS PF00989.25 KER24832.1 - 0.062 13.3 0.3 0.84 9.7 0.0 2.7 3 0 0 3 3 3 0 PAS fold DUF390 PF04094.14 KER24832.1 - 0.18 10.1 3.4 0.25 9.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF3337 PF11816.8 KER24835.1 - 3.5e-28 98.6 0.0 3.3e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 KER24835.1 - 3.4e-26 91.0 19.7 1.2e-05 26.0 0.0 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER24835.1 - 1.1e-08 35.3 1.7 0.15 12.4 0.0 5.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER24835.1 - 0.0066 15.1 7.5 2.2 6.8 0.0 3.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 RAWUL PF16207.5 KER24835.1 - 0.11 13.2 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Paxillin PF03535.13 KER24836.1 - 0.035 14.0 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Paxillin family SNAP PF14938.6 KER24837.1 - 4.4e-17 62.4 9.9 3.5e-16 59.5 7.5 2.1 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KER24837.1 - 0.00038 20.3 10.4 0.98 9.6 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 KER24837.1 - 0.016 14.9 1.3 0.099 12.4 0.3 2.1 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.6 KER24837.1 - 0.035 14.4 16.9 0.84 10.0 2.9 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KER24837.1 - 0.05 13.0 4.5 0.12 11.8 2.2 2.3 1 1 1 3 3 3 0 MalT-like TPR region Sel1 PF08238.12 KER24837.1 - 0.067 13.9 5.4 0.59 10.9 0.0 3.2 3 1 0 3 3 3 0 Sel1 repeat TPR_8 PF13181.6 KER24837.1 - 0.27 11.5 11.4 2.1 8.8 1.6 4.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER24837.1 - 0.43 11.3 5.3 17 6.3 0.4 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KER24837.1 - 6.1 6.9 8.1 6.7 6.7 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER24837.1 - 6.8 7.1 18.2 1.6 9.1 0.3 5.7 3 2 3 7 7 7 0 Tetratricopeptide repeat Peptidase_A17 PF05380.13 KER24838.1 - 8.1e-52 175.5 0.0 1.5e-51 174.6 0.0 1.5 1 0 0 1 1 1 1 Pao retrotransposon peptidase DUF1759 PF03564.15 KER24838.1 - 1.3e-11 44.7 0.0 3.3e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RVT_1 PF00078.27 KER24838.1 - 8.6e-05 22.1 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1758 PF05585.12 KER24838.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 KER24838.1 - 0.00086 19.8 0.1 0.0028 18.2 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER24838.1 - 0.0022 18.6 0.1 0.0067 17.1 0.1 1.9 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KER24838.1 - 0.15 11.9 0.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Wtap PF17098.5 KER24839.1 - 2.3e-31 108.8 0.4 2.3e-31 108.8 0.4 3.0 1 1 1 3 3 3 1 WTAP/Mum2p family INTS2 PF14750.6 KER24839.1 - 0.0055 14.3 0.6 0.0055 14.3 0.6 1.6 2 0 0 2 2 2 1 Integrator complex subunit 2 CENP-K PF11802.8 KER24839.1 - 0.026 14.1 9.1 0.19 11.3 0.5 2.3 2 0 0 2 2 2 0 Centromere-associated protein K T3SSipB PF16535.5 KER24839.1 - 0.062 13.8 4.0 0.091 13.2 3.2 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB OEP PF02321.18 KER24839.1 - 0.067 13.0 5.1 0.086 12.6 1.1 2.4 2 0 0 2 2 2 0 Outer membrane efflux protein AATF-Che1 PF13339.6 KER24839.1 - 0.14 12.8 3.2 0.34 11.6 3.2 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor CENP-F_leu_zip PF10473.9 KER24839.1 - 1.5 8.8 13.7 11 6.1 8.6 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KER24839.1 - 6.3 7.3 16.5 13 6.3 0.2 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region MCM PF00493.23 KER24841.1 - 1e-97 325.6 0.0 1.6e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KER24841.1 - 4e-37 126.9 0.9 7.8e-37 125.9 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER24841.1 - 7.9e-27 93.5 0.2 1.9e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KER24841.1 - 4.7e-16 59.3 0.0 2.1e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KER24841.1 - 1.9e-08 34.4 0.0 6.7e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KER24841.1 - 7.7e-07 28.7 2.8 1.9e-05 24.2 0.0 2.6 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KER24841.1 - 0.00042 20.2 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KER24841.1 - 0.0048 16.6 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain FAM76 PF16046.5 KER24843.1 - 1.2e-58 198.9 20.4 2.6e-58 197.8 20.4 1.5 1 0 0 1 1 1 1 FAM76 protein ATG16 PF08614.11 KER24843.1 - 0.0084 16.3 13.1 0.0084 16.3 13.1 2.9 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF4600 PF15372.6 KER24843.1 - 0.016 15.6 2.9 0.016 15.6 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) zf-FPG_IleRS PF06827.14 KER24843.1 - 1.1 9.1 8.5 0.94 9.4 0.3 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS MPS2 PF17060.5 KER24843.1 - 3.7 6.7 9.3 6.3 6.0 9.1 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 zinc-ribbons_6 PF07191.12 KER24843.1 - 8.1 6.5 16.4 4.8 7.2 0.6 2.6 1 1 1 3 3 3 0 zinc-ribbons IMS PF00817.20 KER24845.1 - 2.6e-40 137.9 0.0 3.6e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family Rh5 PF18515.1 KER24845.1 - 0.21 10.9 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain zf_UBZ PF18439.1 KER24846.1 - 2.1e-11 43.2 0.2 3.6e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KER24846.1 - 1.2e-08 35.6 0.0 3e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Med26 PF08711.11 KER24846.1 - 0.032 14.3 0.5 2.3 8.3 0.1 2.7 1 1 1 2 2 2 0 TFIIS helical bundle-like domain IMS_HHH PF11798.8 KER24846.1 - 0.099 13.0 0.0 0.37 11.2 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif IGFBP PF00219.18 KER24848.1 - 5e-08 33.5 19.3 5e-08 33.5 19.3 4.8 5 2 1 6 6 6 1 Insulin-like growth factor binding protein Protocadherin PF08374.11 KER24849.1 - 0.00055 20.0 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 KER24849.1 - 0.00091 20.1 0.1 0.0011 19.8 0.1 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 KER24849.1 - 0.0016 18.9 0.4 0.0019 18.6 0.4 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Adeno_E3_CR2 PF02439.15 KER24849.1 - 0.0021 17.8 5.5 0.0032 17.2 5.5 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orthoreo_P10 PF07204.11 KER24849.1 - 0.0024 17.8 0.2 0.0031 17.4 0.2 1.3 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 VSP PF03302.13 KER24849.1 - 0.0036 16.2 0.3 0.0041 16.0 0.3 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4006 PF13179.6 KER24849.1 - 0.0061 16.4 0.1 0.008 16.1 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF4006) TRP PF06011.12 KER24849.1 - 0.015 14.0 0.1 0.017 13.8 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Syndecan PF01034.20 KER24849.1 - 0.017 15.0 6.5 0.028 14.3 6.5 1.4 1 1 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 KER24849.1 - 0.017 14.0 0.0 0.018 13.9 0.0 1.0 1 0 0 1 1 1 0 Amnionless Comm PF15957.5 KER24849.1 - 0.019 15.3 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 Commissureless 7TM_GPCR_Srw PF10324.9 KER24849.1 - 0.02 14.2 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw LRR19-TM PF15176.6 KER24849.1 - 0.02 14.8 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Shisa PF13908.6 KER24849.1 - 0.021 15.1 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMIE PF16038.5 KER24849.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 TMIE protein Cadherin_C_2 PF16492.5 KER24849.1 - 0.034 14.9 0.0 0.048 14.4 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal FAM163 PF15069.6 KER24849.1 - 0.037 14.5 0.2 0.046 14.2 0.2 1.1 1 0 0 1 1 1 0 FAM163 family MLANA PF14991.6 KER24849.1 - 0.038 14.3 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A TMEM154 PF15102.6 KER24849.1 - 0.04 13.8 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TMEM132D_C PF15706.5 KER24849.1 - 0.061 13.1 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4446 PF14584.6 KER24849.1 - 0.076 13.0 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LAT PF15234.6 KER24849.1 - 0.08 12.7 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells WBP-1 PF11669.8 KER24849.1 - 0.08 13.6 0.0 0.089 13.4 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Cortexin PF11057.8 KER24849.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney ECSCR PF15820.5 KER24849.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4690 PF15756.5 KER24849.1 - 0.14 12.8 3.7 0.097 13.3 1.9 1.6 1 1 1 2 2 2 0 Small Novel Rich in Cartilage PDGLE PF13190.6 KER24849.1 - 0.38 10.7 1.4 0.45 10.5 0.1 1.7 2 0 0 2 2 2 0 PDGLE domain PARM PF17061.5 KER24849.1 - 0.52 10.4 7.3 0.1 12.8 3.2 1.7 1 1 1 2 2 2 0 PARM Glycophorin_A PF01102.18 KER24849.1 - 0.99 9.7 3.0 1.2 9.4 2.7 1.4 1 1 0 1 1 1 0 Glycophorin A DUF2970 PF11174.8 KER24849.1 - 1.5 8.7 8.8 2.3 8.1 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Mid2 PF04478.12 KER24849.1 - 3.8 7.3 10.3 3.4 7.5 8.8 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor RRM_1 PF00076.22 KER24850.1 - 6.8e-14 51.4 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER24850.1 - 2.3e-06 27.2 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.7 KER24850.1 - 0.042 13.9 0.2 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) SH3_1 PF00018.28 KER24852.1 - 8.6e-06 25.3 0.1 2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SAM_3 PF18016.1 KER24852.1 - 0.017 14.9 0.0 0.053 13.3 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KER24852.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_10 PF17902.1 KER24852.1 - 0.038 14.0 0.1 0.09 12.9 0.1 1.6 1 0 0 1 1 1 0 SH3 domain SH3_3 PF08239.11 KER24852.1 - 0.069 13.4 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_4 PF06347.13 KER24852.1 - 0.16 11.8 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PTB PF08416.13 KER24853.1 - 5.8e-06 26.5 0.4 7.3e-06 26.2 0.4 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Peptidase_C25 PF01364.18 KER24853.1 - 0.17 11.0 0.0 6 5.9 0.0 2.0 1 1 1 2 2 2 0 Peptidase family C25 RVT_1 PF00078.27 KER24854.1 - 3.1e-15 56.3 0.0 5.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KER24854.1 - 0.0082 17.0 0.1 4.1 8.4 0.0 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat HAND PF09110.11 KER24854.1 - 2.7 8.8 6.3 0.17 12.7 0.2 2.2 2 0 0 2 2 2 0 HAND WD40 PF00400.32 KER24855.1 - 2.4e-38 129.4 12.6 1.6e-07 31.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER24855.1 - 4.8e-18 65.2 0.1 4.8e-05 23.6 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER24855.1 - 3.6e-08 32.8 0.5 0.22 10.4 0.0 4.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KER24855.1 - 0.0019 16.8 0.7 0.17 10.4 0.4 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.12 KER24855.1 - 0.0022 17.9 0.8 2.8 8.0 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KER24855.1 - 0.02 14.3 0.2 2.6 7.3 0.0 3.2 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KER24855.1 - 0.027 13.2 0.9 4.3 6.0 0.1 3.0 1 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.9 KER24855.1 - 0.033 13.9 0.3 0.84 9.4 0.1 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 KER24855.1 - 0.47 9.0 3.6 2 7.0 0.3 2.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Adaptin_N PF01602.20 KER24856.1 - 1e-116 390.6 6.4 1.5e-116 390.0 6.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KER24856.1 - 3.4e-53 179.8 0.0 8.3e-53 178.6 0.0 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KER24856.1 - 1.4e-25 89.6 0.0 3.8e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KER24856.1 - 1.1e-13 51.4 4.0 0.00035 20.9 0.0 6.2 3 2 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KER24856.1 - 3.2e-06 27.3 8.3 0.027 14.5 0.5 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KER24856.1 - 8.7e-05 22.5 2.0 0.74 10.2 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KER24856.1 - 0.0078 16.7 4.2 1.9 9.1 0.2 3.5 2 1 0 2 2 2 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KER24856.1 - 0.65 10.6 3.8 13 6.4 0.1 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MOZART1 PF12554.8 KER24857.1 - 2.8e-19 68.6 0.4 3.4e-19 68.4 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated YebG PF07130.12 KER24857.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 YebG protein zf-SNAP50_C PF12251.8 KER24858.1 - 1.9e-58 197.5 0.5 2.7e-58 197.0 0.5 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal XRN_N PF03159.18 KER24859.1 - 1.4e-83 280.0 0.0 2.3e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KER24859.1 - 7.6e-72 242.7 0.5 7.6e-72 242.7 0.5 2.5 2 1 0 2 2 2 1 Xrn1 helical domain SH3_12 PF18129.1 KER24859.1 - 4.2e-15 55.6 0.1 9.2e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 KER24859.1 - 3.7e-09 36.6 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain U3snoRNP10 PF12397.8 KER24859.1 - 0.0081 16.5 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 Guanylate_kin PF00625.21 KER24860.1 - 1.6e-30 106.1 0.0 3e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KER24860.1 - 9.5e-07 28.4 0.0 2.4e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KER24860.1 - 2.8e-06 26.8 0.0 6.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ PF00595.24 KER24860.1 - 3.8e-06 27.2 0.1 7.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 KER24860.1 - 7.6e-06 25.7 2.2 1.1e-05 25.2 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain PDZ_6 PF17820.1 KER24860.1 - 0.00044 20.0 0.1 0.00092 19.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER24860.1 - 0.0032 17.7 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KER24860.1 - 0.033 14.2 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Gp_dh_C PF02800.20 KER24861.1 - 7.8e-69 230.3 0.0 1.2e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KER24861.1 - 5.3e-36 123.0 0.0 1.1e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KER24861.1 - 0.056 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KER24861.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PCI PF01399.27 KER24862.1 - 0.011 16.3 0.2 0.03 14.8 0.2 1.8 1 1 0 1 1 1 0 PCI domain CSN7a_helixI PF18392.1 KER24862.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DUF3699 PF12480.8 KER24862.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Zn_ribbon_17 PF17120.5 KER24863.1 - 5.4e-08 32.3 13.5 6.1e-08 32.2 11.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KER24863.1 - 0.0004 20.7 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain zinc_ribbon_16 PF17034.5 KER24863.1 - 0.0038 17.4 11.8 0.0038 17.4 11.8 2.6 1 1 1 2 2 2 1 Zinc-ribbon like family PhnA_Zn_Ribbon PF08274.12 KER24863.1 - 0.0082 16.1 4.8 0.033 14.2 4.8 2.1 1 0 0 1 1 1 1 PhnA Zinc-Ribbon Cys_rich_CPCC PF14206.6 KER24863.1 - 0.24 11.2 3.4 0.27 11.1 1.2 2.4 1 1 0 1 1 1 0 Cysteine-rich CPCC zf-RRN7 PF11781.8 KER24863.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 YAF2_RYBP PF17219.3 KER24864.1 - 2.4e-08 33.4 0.0 4.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 KER24864.1 - 1.7e-07 30.4 2.5 5.7e-07 28.7 2.5 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KER24864.1 - 0.26 11.6 4.3 0.83 10.0 4.3 1.9 1 0 0 1 1 1 0 C1 domain HECT PF00632.25 KER24868.1 - 3.8e-52 177.7 0.0 1.7e-51 175.6 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.6 KER24868.1 - 1.1e-12 48.2 0.0 2.5e-05 24.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER24868.1 - 5.9e-12 45.6 0.2 1.6e-05 25.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER24868.1 - 3.5e-10 40.3 0.0 1.3e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER24868.1 - 1.3e-08 34.4 0.0 0.013 16.0 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KER24868.1 - 4.1e-06 27.0 0.0 0.0032 17.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Sad1_UNC PF07738.13 KER24868.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal AMP-binding PF00501.28 KER24869.1 - 6.9e-55 186.3 0.2 1e-54 185.8 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AAA_24 PF13479.6 KER24869.1 - 0.12 12.1 0.8 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.28 KER24870.1 - 4.5e-80 269.3 0.1 3.1e-65 220.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Transp_cyt_pur PF02133.15 KER24870.1 - 0.036 12.8 0.3 0.37 9.5 0.0 2.0 2 0 0 2 2 2 0 Permease for cytosine/purines, uracil, thiamine, allantoin AMP-binding_C PF13193.6 KER24870.1 - 0.082 13.9 0.0 0.22 12.5 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SCP2 PF02036.17 KER24871.1 - 2.6e-16 60.0 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short_C2 PF13561.6 KER24871.1 - 6.3e-07 29.2 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER24871.1 - 5.8e-06 25.9 0.0 9.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Alkyl_sulf_C PF14864.6 KER24871.1 - 0.00062 20.0 0.0 0.00089 19.5 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal V-set PF07686.17 KER24872.1 - 1e-13 51.4 9.8 0.067 13.4 0.0 10.3 9 0 0 9 9 9 5 Immunoglobulin V-set domain I-set PF07679.16 KER24872.1 - 5.6e-06 26.3 0.1 2.3 8.3 0.0 7.5 8 0 0 8 8 8 1 Immunoglobulin I-set domain ig PF00047.25 KER24872.1 - 0.0027 17.9 14.5 20 5.5 0.0 8.5 9 1 1 10 10 10 2 Immunoglobulin domain Pkinase PF00069.25 KER24874.1 - 6.6e-41 140.4 0.0 8.6e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24874.1 - 5.2e-15 55.4 0.0 3e-14 53.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER24874.1 - 0.0027 16.7 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER24874.1 - 0.045 13.7 0.1 0.092 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NEXCaM_BD PF16644.5 KER24874.1 - 0.095 13.0 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Pkinase PF00069.25 KER24875.1 - 8.4e-28 97.5 0.0 1.3e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24875.1 - 7.7e-13 48.3 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 KER24875.1 - 9.3e-11 41.7 0.0 2.1e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MyTH4 PF00784.17 KER24876.1 - 3e-14 53.4 0.2 1.4e-07 32.0 0.0 3.0 3 0 0 3 3 3 2 MyTH4 domain PH PF00169.29 KER24876.1 - 5.1e-10 39.8 0.1 0.0016 18.9 0.0 4.0 2 2 0 2 2 2 2 PH domain FERM_M PF00373.18 KER24876.1 - 0.00055 20.3 0.0 0.0018 18.7 0.0 1.8 1 0 0 1 1 1 1 FERM central domain E1_dh PF00676.20 KER24877.1 - 3.5e-81 272.4 0.0 5.2e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KER24877.1 - 4.9e-64 215.3 0.0 7.8e-64 214.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KER24877.1 - 9.9e-50 168.2 0.0 1.6e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal RVT_1 PF00078.27 KER24877.1 - 6.2e-34 117.4 0.0 1.1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxogl_dehyd_N PF16078.5 KER24877.1 - 6.4e-15 54.5 0.3 6.4e-15 54.5 0.3 2.4 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus HLH PF00010.26 KER24881.1 - 3e-14 52.7 0.1 5.2e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain S_4TM PF18159.1 KER24882.1 - 0.059 12.7 2.5 0.08 12.2 2.5 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF2207 PF09972.9 KER24882.1 - 0.18 10.6 1.0 0.24 10.1 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ac81 PF05820.11 KER24882.1 - 0.19 11.3 3.3 0.3 10.7 3.3 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 Tetraspanin PF00335.20 KER24882.1 - 0.29 10.8 3.0 0.29 10.8 2.1 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF3487 PF11990.8 KER24882.1 - 0.3 11.0 5.7 0.5 10.3 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4834 PF16118.5 KER24882.1 - 1.6 9.7 4.0 4.7 8.2 4.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ODV-E18 PF10717.9 KER24882.1 - 2 8.3 8.9 2.9 7.8 4.0 2.3 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3043 PF11241.8 KER24882.1 - 5.2 7.1 5.6 1.2 9.1 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Bestrophin PF01062.21 KER24883.1 - 6.1e-12 45.5 0.0 8.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GPS PF01825.21 KER24884.1 - 0.0059 17.1 2.0 3.8 8.1 0.1 2.5 2 0 0 2 2 2 2 GPCR proteolysis site, GPS, motif DUF3446 PF11928.8 KER24884.1 - 0.15 12.4 2.4 8.3 6.8 0.4 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain Bestrophin PF01062.21 KER24886.1 - 6e-59 199.9 1.0 7.1e-59 199.6 1.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Vut_1 PF02592.15 KER24886.1 - 0.02 15.2 0.3 0.039 14.3 0.3 1.4 1 0 0 1 1 1 0 Putative vitamin uptake transporter MmcB-like PF06319.12 KER24886.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein MmcB-like Bestrophin PF01062.21 KER24887.1 - 1.3e-44 152.8 6.0 1.5e-44 152.6 6.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4140 PF13600.6 KER24889.1 - 1.3e-05 25.6 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Cupin_6 PF12852.7 KER24889.1 - 0.071 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Cupin DUF4139 PF13598.6 KER24890.1 - 2.1e-38 132.1 0.0 3.3e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KER24890.1 - 1.6e-09 38.1 9.3 0.00047 20.6 0.2 3.4 3 0 0 3 3 3 2 N-terminal domain of unknown function (DUF4140) Top6b_C PF18000.1 KER24890.1 - 0.002 18.3 0.2 0.0049 17.0 0.0 1.8 2 0 0 2 2 1 1 Type 2 DNA topoisomerase 6 subunit B C-terminal domain TMF_TATA_bd PF12325.8 KER24890.1 - 0.018 15.3 8.7 8.2 6.7 1.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding ComGF PF15980.5 KER24890.1 - 0.039 14.3 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Putative Competence protein ComGF MCC-bdg_PDZ PF10506.9 KER24890.1 - 0.051 13.6 3.3 8.7 6.4 0.1 3.0 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 KER24890.1 - 0.066 13.2 2.8 0.86 9.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KER24890.1 - 0.068 11.1 3.1 9.7 4.0 0.0 3.0 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 KER24890.1 - 0.074 13.5 3.7 67 3.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF2935 PF11155.8 KER24890.1 - 0.074 13.4 0.1 19 5.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) zf-C4H2 PF10146.9 KER24890.1 - 0.085 13.1 2.0 0.56 10.5 2.0 2.3 1 0 0 1 1 1 0 Zinc finger-containing protein PspA_IM30 PF04012.12 KER24890.1 - 0.1 12.2 12.0 0.14 11.8 2.4 3.1 3 0 0 3 3 3 0 PspA/IM30 family SOG2 PF10428.9 KER24890.1 - 0.13 11.5 13.2 4 6.5 0.1 3.2 3 0 0 3 3 3 0 RAM signalling pathway protein Prefoldin_2 PF01920.20 KER24890.1 - 0.29 11.1 6.5 32 4.5 2.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit DUF4446 PF14584.6 KER24890.1 - 0.29 11.1 2.3 0.39 10.7 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF489 PF04356.12 KER24890.1 - 0.34 10.9 1.8 2.9 7.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Fungal_TACC PF12709.7 KER24890.1 - 0.42 11.1 4.6 56 4.3 0.5 3.3 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Tropomyosin_1 PF12718.7 KER24890.1 - 0.83 9.8 12.3 0.044 13.9 3.2 2.8 3 0 0 3 3 3 0 Tropomyosin like DUF948 PF06103.11 KER24890.1 - 0.9 9.8 4.5 39 4.6 0.2 3.5 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 KER24890.1 - 1.8 8.2 9.8 11 5.7 0.3 3.3 3 0 0 3 3 3 0 Laminin Domain I Fib_alpha PF08702.10 KER24890.1 - 2.2 8.5 5.1 10 6.3 0.2 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KER24890.1 - 2.9 8.4 14.3 5 7.7 2.5 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region KfrA_N PF11740.8 KER24890.1 - 3.2 8.5 9.3 48 4.7 0.5 3.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Takusan PF04822.13 KER24890.1 - 4.4 7.3 9.7 14 5.6 0.1 3.2 3 0 0 3 3 3 0 Takusan Gag_p12 PF01141.18 KER24890.1 - 4.5 7.7 9.4 18 5.8 0.2 3.4 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 SlyX PF04102.12 KER24890.1 - 8.3 7.1 11.0 8.8 7.0 2.4 3.3 3 0 0 3 3 3 0 SlyX Lig_chan-Glu_bd PF10613.9 KER24891.1 - 8.3e-19 67.9 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KER24891.1 - 2.1e-09 37.2 0.0 6.9e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SNAD2 PF18745.1 KER24892.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 Ribosomal_S26e PF01283.19 KER24893.1 - 4.9e-24 84.8 1.8 5.7e-24 84.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Adeno_VII PF03228.14 KER24893.1 - 0.021 15.5 0.5 0.024 15.3 0.5 1.0 1 0 0 1 1 1 0 Adenoviral core protein VII dCMP_cyt_deam_1 PF00383.23 KER24894.1 - 2.1e-21 75.7 0.0 7.2e-19 67.5 0.1 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region RVT_1 PF00078.27 KER24894.1 - 1.7e-17 63.7 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MafB19-deam PF14437.6 KER24894.1 - 4.6e-09 36.1 0.0 8.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KER24894.1 - 0.04 14.0 0.2 0.19 11.8 0.2 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KER24894.1 - 0.087 12.9 0.5 0.4 10.8 0.2 2.1 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KER24894.1 - 0.21 11.6 0.6 0.87 9.6 0.1 2.2 3 0 0 3 3 3 0 APOBEC2 tRNA-synt_1c PF00749.21 KER24895.1 - 5.3e-42 143.8 0.0 1.6e-30 106.1 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain S-AdoMet_synt_C PF02773.16 KER24897.1 - 9.5e-68 226.5 0.0 1e-66 223.1 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KER24897.1 - 2.4e-46 156.9 0.0 4.2e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KER24897.1 - 2.7e-41 140.3 0.0 5.6e-41 139.2 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain FR47 PF08445.10 KER24897.1 - 0.051 13.5 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein AdoMet_Synthase PF01941.19 KER24897.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Ig_3 PF13927.6 KER24900.1 - 4e-39 133.1 3.0 4.9e-12 46.3 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 KER24900.1 - 4.4e-28 97.2 0.0 1.8e-09 37.6 0.0 4.9 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KER24900.1 - 4e-26 91.2 2.6 1.4e-07 31.7 0.0 5.9 4 2 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 KER24900.1 - 2.7e-22 78.8 0.1 1.5e-05 25.1 0.0 5.0 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KER24900.1 - 8.6e-10 38.8 2.1 0.36 11.2 0.0 5.8 5 0 0 5 5 5 3 Fibronectin type III domain V-set PF07686.17 KER24900.1 - 1.8e-09 37.7 0.5 0.021 15.0 0.0 5.4 4 1 0 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KER24900.1 - 5.7e-05 22.6 0.0 0.063 12.9 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER24900.1 - 8.5e-05 22.5 0.0 0.029 14.4 0.0 3.7 4 0 0 4 4 3 1 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 KER24900.1 - 0.0025 17.8 4.6 2.5 8.3 0.0 5.1 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 KER24900.1 - 0.016 15.4 0.0 2.4 8.4 0.0 3.0 2 0 0 2 2 2 0 Fibronectin type III domain Ig_5 PF16681.5 KER24900.1 - 0.072 13.5 0.0 35 4.9 0.0 4.5 5 2 0 5 5 5 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Sulfotransfer_4 PF17784.1 KER24901.1 - 4.9e-51 173.6 0.0 6.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER24901.1 - 3.4e-06 27.6 0.6 0.025 15.0 0.1 2.7 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER24901.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.7 2 1 0 2 2 2 0 Sulfotransferase domain Acyl_transf_3 PF01757.22 KER24903.1 - 4.2e-20 72.1 40.6 4.2e-20 72.1 40.6 1.8 3 0 0 3 3 3 1 Acyltransferase family Mpv17_PMP22 PF04117.12 KER24905.1 - 2.6e-18 66.0 1.1 4.7e-18 65.2 1.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KER24906.1 - 1.5e-19 70.0 0.3 2.6e-19 69.2 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family C2 PF00168.30 KER24907.1 - 0.00042 20.6 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain RT_RNaseH_2 PF17919.1 KER24909.1 - 5e-13 49.0 0.0 8.3e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER24909.1 - 1.7e-05 25.1 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ion_trans PF00520.31 KER24910.1 - 2.8e-41 141.4 6.6 3.6e-41 141.0 6.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER24910.1 - 5.2e-24 84.4 0.0 1.2e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER24910.1 - 9.8e-14 51.1 0.3 9.8e-14 51.1 0.3 1.8 2 0 0 2 2 2 1 Ion channel DCP1 PF06058.13 KER24915.1 - 2.6e-34 117.6 0.1 5.2e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 KER24915.1 - 1.4e-14 53.0 0.5 2.8e-14 52.1 0.5 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus zf-RING_2 PF13639.6 KER24917.1 - 9.8e-12 45.0 7.3 2.1e-11 43.9 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KER24917.1 - 5.5e-10 38.8 2.8 1.6e-09 37.4 2.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KER24917.1 - 4.2e-07 30.1 7.3 1.3e-06 28.6 7.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KER24917.1 - 4.6e-07 29.6 7.6 8.8e-07 28.7 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER24917.1 - 6.3e-07 29.2 3.3 1.2e-06 28.4 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER24917.1 - 7.9e-07 28.8 5.8 1.5e-06 28.0 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER24917.1 - 0.00018 21.5 5.4 0.00039 20.4 5.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KER24917.1 - 0.00088 19.1 3.8 0.0015 18.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER24917.1 - 0.0026 17.8 2.0 0.0086 16.1 2.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KER24917.1 - 0.003 17.4 4.0 0.006 16.4 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CrgA PF06781.12 KER24917.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein CrgA PspB PF06667.12 KER24917.1 - 0.014 15.4 0.4 0.028 14.5 0.4 1.4 1 0 0 1 1 1 0 Phage shock protein B RINGv PF12906.7 KER24917.1 - 0.34 11.1 4.3 3 8.1 4.5 2.3 2 0 0 2 2 2 0 RING-variant domain PP1c_bdg PF10488.9 KER24917.1 - 0.47 9.9 1.9 0.91 9.0 1.9 1.4 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Pkinase PF00069.25 KER24920.1 - 4.4e-72 242.6 0.0 6e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER24920.1 - 7.4e-42 143.4 0.0 1.1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB2 PF18409.1 KER24920.1 - 7.4e-29 100.6 0.0 5.5e-28 97.8 0.0 2.5 3 0 0 3 3 3 1 Polo-like Kinase 4 Polo Box 2 Plk4_PB1 PF18190.1 KER24920.1 - 1.9e-24 85.9 2.2 2.7e-20 72.5 0.8 3.7 2 1 0 2 2 2 1 Polo-like Kinase 4 Polo Box 1 POLO_box PF00659.18 KER24920.1 - 1e-07 32.1 0.0 7.1e-07 29.3 0.0 2.5 3 0 0 3 3 3 1 POLO box duplicated region Kinase-like PF14531.6 KER24920.1 - 5.8e-05 22.6 0.0 0.0002 20.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER24920.1 - 0.00011 21.1 0.1 0.0002 20.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER24920.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4520 PF15016.6 KER24920.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) RIO1 PF01163.22 KER24920.1 - 0.08 12.5 0.2 0.61 9.6 0.1 2.2 2 1 0 2 2 2 0 RIO1 family IQ PF00612.27 KER24922.1 - 3.2e-05 23.3 4.7 0.00014 21.3 4.7 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1664 PF07889.12 KER24922.1 - 0.58 10.2 14.8 2.8 8.0 6.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KER24922.1 - 2.8 8.5 36.0 2.8 8.5 11.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3708 PF12501.8 KER24922.1 - 4.1 7.2 6.3 2.9 7.7 0.7 2.9 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter OmpH PF03938.14 KER24922.1 - 7.5 6.9 31.9 0.63 10.4 14.8 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LIM PF00412.22 KER24923.1 - 7.7e-26 90.1 21.7 6.8e-14 51.8 5.0 2.1 2 0 0 2 2 2 2 LIM domain SopA_C PF13979.6 KER24923.1 - 0.00029 20.6 0.1 0.00036 20.3 0.1 1.2 1 0 0 1 1 1 1 SopA-like catalytic domain PolC_DP2 PF03833.13 KER24923.1 - 3.9 5.2 7.4 4.3 5.1 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 ATP-synt_G PF04718.15 KER24926.1 - 7.8e-22 78.0 0.0 9e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit RRM_1 PF00076.22 KER24928.1 - 1.9e-45 152.6 0.0 1.9e-20 72.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER24928.1 - 1.1e-08 35.1 0.1 0.0025 17.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KER24928.1 - 0.0048 16.7 0.0 2.6 8.0 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1513 PF07433.11 KER24928.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Lysyl_oxidase PF01186.17 KER24929.1 - 9.5e-83 276.9 0.2 9.5e-83 276.9 0.2 1.5 2 0 0 2 2 2 1 Lysyl oxidase SRCR PF00530.18 KER24929.1 - 2.7e-34 117.7 4.5 1.3e-23 83.3 0.7 2.8 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KER24929.1 - 0.00013 22.4 2.9 0.018 15.6 0.6 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DHC_N1 PF08385.12 KER24932.1 - 0.00085 18.1 0.1 0.0031 16.2 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 SHQ1 PF04925.15 KER24932.1 - 0.038 13.6 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 SHQ1 protein DUF5039 PF16442.5 KER24932.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) DHC_N1 PF08385.12 KER24933.1 - 5.1e-95 319.2 0.0 9.6e-95 318.3 0.0 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CDI PF02234.19 KER24935.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Raptor_N PF14538.6 KER24935.1 - 0.088 12.8 0.4 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain MIF4G PF02854.19 KER24937.1 - 5.8e-20 71.8 0.3 1.3e-19 70.7 0.3 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KER24937.1 - 1.3e-14 54.2 1.1 3.2e-10 40.0 0.0 3.2 3 0 0 3 3 3 2 MA3 domain Cnd1 PF12717.7 KER24937.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ADP_PFK_GK PF04587.15 KER24938.1 - 5.4e-88 295.4 0.0 4e-32 111.3 0.0 5.8 5 1 0 5 5 5 5 ADP-specific Phosphofructokinase/Glucokinase conserved region MULE PF10551.9 KER24938.1 - 5.3e-14 52.4 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain RNase_H2-Ydr279 PF09468.10 KER24941.1 - 8.1e-12 45.6 0.1 1.6e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KER24941.1 - 8.6e-10 38.7 0.0 6.9e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain adh_short PF00106.25 KER24942.1 - 2.4e-25 89.1 2.8 1.9e-13 50.3 1.2 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KER24942.1 - 9e-18 64.7 4.0 4.1e-10 39.6 2.5 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER24942.1 - 2.2e-06 27.7 0.3 1.1e-05 25.4 0.3 1.9 2 0 0 2 2 2 1 KR domain DGC PF08859.11 KER24942.1 - 0.062 13.4 0.1 4.7 7.4 0.0 3.0 3 0 0 3 3 3 0 DGC domain THF_DHG_CYH_C PF02882.19 KER24942.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Caud_tail_N PF16838.5 KER24943.1 - 0.022 15.2 1.0 7.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Caudoviral major tail protein N-terminus PTB PF08416.13 KER24943.1 - 0.071 13.3 2.0 11 6.1 0.1 2.4 2 0 0 2 2 2 0 Phosphotyrosine-binding domain PIP49_C PF12260.8 KER24945.1 - 0.89 9.2 13.0 0.88 9.2 1.9 2.4 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Nbl1_Borealin_N PF10444.9 KER24946.1 - 0.0074 15.9 0.2 5.3 6.8 0.0 2.4 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal CwsA PF10814.8 KER24946.1 - 0.1 12.8 1.4 5.5 7.2 0.1 2.1 1 1 0 2 2 2 0 Cell wall synthesis protein CwsA NUDIX PF00293.28 KER24947.1 - 1.7e-06 28.1 0.0 2.1e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain Synaptobrevin PF00957.21 KER24948.1 - 2.6e-31 107.3 1.5 4.1e-31 106.6 1.5 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF945 PF06097.11 KER24948.1 - 0.072 12.2 0.5 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF2976 PF11190.8 KER24948.1 - 0.074 12.9 0.7 0.16 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) TPR_21 PF09976.9 KER24948.1 - 0.11 12.2 1.1 0.17 11.5 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain FeoB_associated PF12669.7 KER24948.1 - 0.12 12.8 0.9 0.23 11.9 0.9 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF515 PF04415.12 KER24948.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GCK PF07802.11 KER24949.1 - 0.0066 16.8 1.9 0.013 15.9 1.9 1.4 1 0 0 1 1 1 1 GCK domain Cmc1 PF08583.10 KER24949.1 - 0.0097 15.9 1.1 0.016 15.2 1.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like dDENN PF03455.19 KER24949.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 dDENN domain Rhodanese PF00581.20 KER24954.1 - 1.6e-14 54.4 0.0 3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CdiI PF07262.11 KER24955.1 - 0.055 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein IL4_i_Ig PF18258.1 KER24956.1 - 8.2e-28 96.5 1.8 1.4e-27 95.7 1.8 1.4 1 0 0 1 1 1 1 Interleukin-4 inducing immunoglobulin-binding domain Crystall PF00030.19 KER24956.1 - 0.0072 16.5 0.2 0.052 13.8 0.2 2.2 1 1 0 1 1 1 1 Beta/Gamma crystallin CBF PF03914.17 KER24957.1 - 3.4e-22 79.3 0.3 7.3e-22 78.2 0.1 1.6 2 0 0 2 2 2 1 CBF/Mak21 family CPBP PF02517.16 KER24957.1 - 8.5e-11 42.1 4.4 2.2e-10 40.8 4.4 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease DUF1330 PF07045.11 KER24959.1 - 3.8e-07 30.4 0.0 0.0074 16.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) zf-C2HC_2 PF13913.6 KER24960.1 - 0.00064 19.6 3.3 0.078 12.9 0.1 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 KER24960.1 - 0.045 14.2 1.1 2 9.0 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER24960.1 - 0.11 13.4 3.9 8.1 7.6 0.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER24960.1 - 4.1 7.8 6.9 5.7 7.3 0.1 3.6 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Pes-10 PF07149.11 KER24961.1 - 0.0024 17.0 15.1 0.0028 16.8 15.1 1.0 1 0 0 1 1 1 1 Pes-10 DNA_pol_phi PF04931.13 KER24961.1 - 0.088 10.9 34.9 0.11 10.6 34.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KER24961.1 - 0.094 10.9 24.7 0.1 10.8 24.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KER24961.1 - 0.12 10.6 16.0 0.14 10.4 16.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KER24961.1 - 0.15 10.5 16.5 0.16 10.4 16.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Med8 PF10232.9 KER24961.1 - 0.16 11.5 0.2 0.21 11.2 0.2 1.3 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CNDH2_C PF16858.5 KER24961.1 - 1.2 9.0 11.1 1.4 8.8 11.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term eIF-3c_N PF05470.12 KER24961.1 - 2.5 6.3 10.3 2.7 6.2 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cnd2 PF05786.14 KER24961.1 - 6.5 5.3 19.2 8.2 4.9 19.2 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 EGF PF00008.27 KER24963.1 - 8.3e-11 42.0 18.1 2.2e-05 24.6 5.7 3.8 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KER24963.1 - 4.3e-05 24.0 16.5 0.00073 20.1 3.7 3.7 2 1 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.13 KER24963.1 - 0.00078 19.8 19.8 0.11 12.9 7.3 3.4 2 1 0 2 2 2 2 EGF-like domain Nop14 PF04147.12 KER24963.1 - 0.001 17.4 29.0 0.0013 17.0 29.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 KER24963.1 - 0.0011 18.5 29.2 0.0014 18.1 29.2 1.1 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 KER24963.1 - 0.0078 14.4 42.2 0.012 13.8 42.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 KER24963.1 - 0.0085 14.4 21.7 0.012 13.9 21.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 KER24963.1 - 0.0094 14.5 19.5 0.012 14.1 19.5 1.1 1 0 0 1 1 1 1 Mpp10 protein SAPS PF04499.15 KER24963.1 - 0.12 11.1 6.8 0.17 10.7 6.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KER24963.1 - 0.63 9.3 28.1 0.82 8.9 28.1 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 KER24963.1 - 0.67 9.3 25.4 0.93 8.8 25.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIF_alpha PF05793.12 KER24963.1 - 1.8 7.1 28.3 2.4 6.7 28.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop25 PF09805.9 KER24963.1 - 5.5 7.5 15.2 10 6.6 15.2 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SpoIIIAH PF12685.7 KER24963.1 - 6 6.6 10.3 8.7 6.1 10.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Ank_2 PF12796.7 KER24964.1 - 3e-19 69.4 0.2 2.7e-06 27.9 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Notch PF00066.17 KER24964.1 - 5.6e-19 68.3 36.3 1.3e-09 38.4 9.9 4.2 3 0 0 3 3 3 2 LNR domain Ank_3 PF13606.6 KER24964.1 - 1.1e-06 28.5 0.3 0.077 13.6 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KER24964.1 - 2.9e-06 27.7 1.4 0.024 15.2 0.0 4.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KER24964.1 - 7.6e-06 26.1 0.1 0.011 16.1 0.0 4.1 3 1 0 3 3 3 1 Ankyrin repeat EGF PF00008.27 KER24964.1 - 8e-06 26.1 21.6 4e-05 23.8 10.2 6.6 7 1 0 7 7 4 3 EGF-like domain hEGF PF12661.7 KER24964.1 - 4e-05 24.1 6.4 4e-05 24.1 6.4 6.9 7 0 0 7 7 5 2 Human growth factor-like EGF Ank_5 PF13857.6 KER24964.1 - 4.4e-05 23.7 4.6 0.15 12.4 0.1 5.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) CDC45 PF02724.14 KER24964.1 - 0.0018 16.7 9.1 0.0035 15.7 9.1 1.4 1 0 0 1 1 1 1 CDC45-like protein Hjc PF01870.18 KER24964.1 - 0.012 15.6 0.0 0.057 13.4 0.1 2.0 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Nop14 PF04147.12 KER24964.1 - 0.017 13.4 22.7 0.01 14.1 19.8 1.8 2 0 0 2 2 2 0 Nop14-like family NOD PF06816.13 KER24964.1 - 0.15 11.7 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 NOTCH protein DNA_pol_phi PF04931.13 KER24964.1 - 1.7 6.7 45.7 2.5 6.1 45.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 KER24964.1 - 7.6 6.4 18.0 19 5.1 18.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KER24965.1 - 0.001 18.4 4.6 0.0012 18.3 4.6 1.2 1 0 0 1 1 1 1 NOA36 protein Cwf_Cwc_15 PF04889.12 KER24965.1 - 0.0099 15.6 2.9 0.012 15.4 2.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 KER24965.1 - 0.2 11.7 0.5 0.26 11.3 0.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 KER24965.1 - 2.4 8.0 4.6 3.6 7.4 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KER24965.1 - 2.5 8.6 18.9 4.1 7.8 18.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KER24965.1 - 6.1 4.8 13.1 7.9 4.4 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ion_trans PF00520.31 KER24966.1 - 1.5e-17 63.7 10.0 2e-17 63.3 10.0 1.1 1 0 0 1 1 1 1 Ion transport protein PsbL PF02419.17 KER24966.1 - 0.076 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 PsbL protein FA PF08736.11 KER24967.1 - 7.4 6.7 9.7 9.9 6.3 0.1 3.5 3 0 0 3 3 3 0 FERM adjacent (FA) Ski_Sno PF02437.17 KER24968.1 - 4e-36 123.0 0.0 5.9e-36 122.5 0.0 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family Ribosomal_L37ae PF01780.19 KER24969.1 - 1.1e-39 134.4 7.8 1.2e-39 134.2 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_2 PF03107.16 KER24969.1 - 0.00042 20.6 3.3 0.14 12.5 0.2 2.1 1 1 1 2 2 2 2 C1 domain Zn_Tnp_IS1595 PF12760.7 KER24969.1 - 0.0048 16.9 1.5 0.0098 15.9 1.5 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 KER24969.1 - 0.04 14.0 6.0 0.72 9.9 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.6 KER24969.1 - 0.041 13.3 2.4 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KER24969.1 - 0.51 10.1 5.3 0.54 10.0 0.2 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 KER24969.1 - 2.2 8.9 6.7 13 6.5 1.0 2.4 1 1 1 2 2 2 0 Zinc-finger double domain Cullin_binding PF03556.15 KER24970.1 - 1.3e-33 115.9 0.5 1.3e-33 115.9 0.5 1.6 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KER24970.1 - 9.9e-12 44.5 0.0 2.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KER24970.1 - 0.0017 18.0 0.4 0.0037 16.9 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain Rootletin PF15035.6 KER24971.1 - 3.7e-43 147.8 22.6 3.7e-43 147.8 22.6 14.0 3 3 9 12 12 12 2 Ciliary rootlet component, centrosome cohesion EzrA PF06160.12 KER24971.1 - 0.0012 17.1 32.0 0.0012 17.1 32.0 10.3 3 3 6 12 12 12 4 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KER24971.1 - 0.0018 18.3 23.8 0.0018 18.3 23.8 16.7 4 3 8 15 15 15 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4602 PF15375.6 KER24973.1 - 6e-15 55.8 1.2 6.6e-15 55.6 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Proteasome PF00227.26 KER24978.1 - 0.0015 18.0 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane PF00664.23 KER24979.1 - 1.7e-95 319.8 32.0 3.4e-51 174.5 10.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KER24979.1 - 5.7e-66 221.2 0.0 1.4e-33 116.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KER24979.1 - 1.1e-16 61.0 3.7 4.2e-07 29.6 0.1 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KER24979.1 - 3.2e-12 47.1 1.1 5.4e-05 23.6 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KER24979.1 - 1.7e-09 38.1 1.1 0.0064 16.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KER24979.1 - 5.6e-08 32.9 0.0 0.2 11.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KER24979.1 - 6.6e-08 32.2 0.0 0.0074 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER24979.1 - 1.3e-07 31.7 0.0 0.024 14.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KER24979.1 - 3.4e-07 29.7 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KER24979.1 - 3.5e-07 30.1 0.1 0.059 13.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KER24979.1 - 3.5e-07 29.9 0.0 0.028 14.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 KER24979.1 - 9.4e-07 28.0 0.2 0.025 13.4 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KER24979.1 - 1.2e-06 28.0 0.5 0.13 11.6 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin AAA_15 PF13175.6 KER24979.1 - 9.3e-06 25.6 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KER24979.1 - 1.4e-05 25.5 0.9 2.4 8.6 0.1 4.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER24979.1 - 1.9e-05 24.7 0.1 0.37 10.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 KER24979.1 - 4.7e-05 23.4 0.1 0.35 10.8 0.0 3.4 3 0 0 3 3 3 2 NACHT domain SbcCD_C PF13558.6 KER24979.1 - 5.3e-05 23.4 5.9 0.057 13.7 0.5 4.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KER24979.1 - 0.00013 21.8 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KER24979.1 - 0.00019 21.2 1.7 3 7.6 0.0 4.4 5 0 0 5 5 4 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KER24979.1 - 0.00023 20.9 0.4 7 6.3 0.0 3.7 4 0 0 4 4 3 0 Sigma-54 interaction domain NB-ARC PF00931.22 KER24979.1 - 0.00027 20.2 0.1 1 8.5 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.6 KER24979.1 - 0.00028 20.5 0.3 1.7 8.2 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 KER24979.1 - 0.00028 21.4 0.0 0.27 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KER24979.1 - 0.0004 20.9 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KER24979.1 - 0.00055 19.2 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 KER24979.1 - 0.00058 19.8 0.1 0.72 9.8 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KER24979.1 - 0.00061 19.8 0.0 0.26 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KER24979.1 - 0.0013 18.9 0.4 0.92 9.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 KER24979.1 - 0.0025 17.6 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 KER24979.1 - 0.0037 17.3 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KER24979.1 - 0.0038 17.6 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 KER24979.1 - 0.0075 16.0 0.5 0.69 9.7 0.1 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KER24979.1 - 0.0078 16.4 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 KER24979.1 - 0.0088 16.5 0.0 4.9 7.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 KER24979.1 - 0.0088 15.7 0.0 2.3 7.8 0.0 2.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 KER24979.1 - 0.0097 16.0 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 KER24979.1 - 0.011 16.0 0.0 7.9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KER24979.1 - 0.019 15.0 0.0 7.6 6.5 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 KER24979.1 - 0.019 14.7 0.0 0.77 9.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase APS_kinase PF01583.20 KER24979.1 - 0.019 14.8 0.0 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KER24979.1 - 0.03 14.2 0.1 14 5.5 0.0 3.2 4 0 0 4 4 3 0 NTPase ATP_bind_1 PF03029.17 KER24979.1 - 0.043 13.6 0.1 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TniB PF05621.11 KER24979.1 - 0.063 12.7 0.0 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein FumaraseC_C PF10415.9 KER24979.1 - 0.07 13.6 0.2 2 8.9 0.0 3.1 3 0 0 3 3 2 0 Fumarase C C-terminus Proteasome PF00227.26 KER24981.1 - 6.4e-46 156.3 0.0 9.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KER24981.1 - 7.3e-13 47.9 0.0 1.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cyclin_C_2 PF16899.5 KER24981.1 - 1.2e-09 38.5 0.0 4.3e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KER24981.1 - 5.9e-08 32.5 0.0 1.7e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain YceD PF02620.17 KER24981.1 - 0.018 15.2 0.7 0.043 13.9 0.7 1.6 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD RVT_1 PF00078.27 KER24983.1 - 0.027 14.0 0.0 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) WW PF00397.26 KER24984.1 - 4.6e-12 45.8 2.0 1.7e-11 44.0 2.0 2.1 1 0 0 1 1 1 1 WW domain Cystatin PF00031.21 KER24985.1 - 3.4e-05 24.0 0.1 5.9e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Cystatin domain Cathelicidins PF00666.17 KER24985.1 - 0.09 13.1 0.1 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Cathelicidin Urb2 PF10441.9 KER24986.1 - 0.06 13.3 0.0 3.2 7.6 0.0 2.0 2 0 0 2 2 2 0 Urb2/Npa2 family Cohesin_load PF10345.9 KER24988.1 - 2e-69 234.6 3.6 1.9e-68 231.4 2.1 2.0 2 0 0 2 2 2 1 Cohesin loading factor TPR_14 PF13428.6 KER24988.1 - 0.00011 22.7 1.4 29 5.8 0.5 6.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER24988.1 - 0.00019 20.9 14.3 0.0026 17.2 0.2 4.9 2 2 2 4 4 4 2 MalT-like TPR region TPR_8 PF13181.6 KER24988.1 - 0.0047 17.0 0.3 21 5.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER24988.1 - 0.011 15.8 0.0 18 5.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KER24988.1 - 0.071 13.8 2.4 19 6.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Ku PF02735.16 KER24990.1 - 2e-43 148.5 0.0 3.6e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Peptidase_S9 PF00326.21 KER24990.1 - 1.3e-30 106.5 0.0 2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ku_N PF03731.15 KER24990.1 - 5.5e-29 101.5 0.0 8.3e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KER24990.1 - 3.5e-14 53.2 0.1 8e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Hydrolase_4 PF12146.8 KER24990.1 - 1.1e-08 34.7 0.0 4.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KER24990.1 - 1.5e-07 31.4 0.2 3.4e-07 30.2 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER24990.1 - 3.3e-05 24.6 1.2 3.3e-05 24.6 1.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.12 KER24990.1 - 0.0032 17.4 1.5 0.027 14.4 0.0 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat SAP PF02037.27 KER24990.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 SAP domain Abhydrolase_2 PF02230.16 KER24990.1 - 0.013 15.3 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KER24990.1 - 0.032 13.9 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Baculo_LEF5_C PF11792.8 KER24990.1 - 0.045 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain ELL PF10390.9 KER24990.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF21 PF01595.20 KER24991.1 - 7.5e-35 120.2 1.4 1.4e-34 119.3 1.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KER24991.1 - 3.6e-05 24.1 0.3 0.008 16.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain EGF PF00008.27 KER24992.1 - 0.0015 18.8 18.0 1.3 9.4 0.6 6.0 5 0 0 5 5 5 3 EGF-like domain DUF4722 PF15849.5 KER24992.1 - 0.063 13.0 0.7 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) Laminin_EGF PF00053.24 KER24992.1 - 0.094 12.9 19.1 0.27 11.4 2.7 4.7 4 0 0 4 4 4 0 Laminin EGF domain EGF_2 PF07974.13 KER24992.1 - 9.3 6.7 27.9 0.12 12.8 1.7 4.9 5 1 0 5 5 5 0 EGF-like domain EGF PF00008.27 KER24993.1 - 0.0056 17.0 15.6 0.79 10.1 0.1 5.6 5 0 0 5 5 5 2 EGF-like domain EGF_2 PF07974.13 KER24993.1 - 0.0081 16.5 17.4 0.019 15.4 0.1 4.6 4 1 0 4 4 4 2 EGF-like domain Laminin_EGF PF00053.24 KER24993.1 - 0.019 15.1 19.7 0.021 14.9 3.2 4.7 4 1 1 5 5 5 0 Laminin EGF domain HSP90 PF00183.18 KER24995.1 - 4.4e-96 322.8 0.0 2.6e-93 313.7 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KER24995.1 - 7.6e-11 42.0 0.1 1.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KER24995.1 - 3.4e-07 30.8 0.2 6.2e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2H2_4 PF13894.6 KER24997.1 - 4.5e-09 36.4 50.4 0.066 14.1 0.4 10.1 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KER24997.1 - 8.8e-08 32.2 53.9 0.0042 17.5 0.8 10.1 10 0 0 10 10 10 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER24997.1 - 9.5e-06 25.8 3.8 0.00015 22.0 1.7 8.6 9 0 0 9 9 8 3 Zinc-finger double domain FOXP-CC PF16159.5 KER24997.1 - 0.00025 21.6 26.7 2.3 8.9 0.1 7.5 5 1 2 7 7 7 2 FOXP coiled-coil domain zf-Di19 PF05605.12 KER24997.1 - 0.0049 17.1 29.0 0.011 16.0 4.4 6.3 6 1 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KER24997.1 - 0.026 14.2 5.1 9.6 5.9 0.1 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KER24997.1 - 0.027 14.9 32.0 0.28 11.7 0.6 6.2 4 1 1 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_9 PF16293.5 KER24997.1 - 0.032 14.1 6.0 37 4.3 0.0 5.4 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) DUF2321 PF10083.9 KER24997.1 - 0.04 13.5 3.8 0.077 12.6 0.3 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-C2H2_12 PF18112.1 KER24997.1 - 0.12 12.8 6.3 5.5 7.6 0.0 5.0 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KER24997.1 - 0.42 10.4 0.1 0.046 13.5 1.4 6.4 8 0 0 8 8 7 0 C2H2-type zinc-finger domain Zap1_zf2 PF18217.1 KER24997.1 - 0.81 9.7 16.6 0.12 12.4 0.7 3.7 3 0 0 3 3 3 0 Zap1 zinc finger 2 SIR2 PF02146.17 KER24997.1 - 1 9.3 3.0 2.5 8.0 2.5 1.9 1 1 0 1 1 1 0 Sir2 family zf-C2H2_12 PF18658.1 KER24997.1 - 3 7.5 17.6 1.4 8.5 0.0 6.1 4 2 1 6 6 6 0 Zinc-finger C2H2-type zf-met PF12874.7 KER24997.1 - 5.3 7.6 19.1 2.4 8.7 0.0 6.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-Nse PF11789.8 KER24997.1 - 5.4 6.9 6.9 2.7 7.9 3.2 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit OrsD PF12013.8 KER24997.1 - 5.7 7.4 30.0 6.6 7.2 1.4 6.5 4 1 2 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D Melibiase_2 PF16499.5 KER24999.1 - 7.1e-126 419.1 1.8 8.6e-126 418.9 1.8 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 KER24999.1 - 3.3e-10 40.0 0.0 6.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 KER24999.1 - 1.1e-05 25.4 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KER24999.1 - 1.1e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Melibiase UQ_con PF00179.26 KER25000.1 - 1.7e-13 50.4 0.1 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RVT_1 PF00078.27 KER25000.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tfb5 PF06331.12 KER25001.1 - 1.7e-13 50.3 0.1 2.5e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 RVT_1 PF00078.27 KER25001.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) G-alpha PF00503.20 KER25002.1 - 2e-75 254.2 18.0 5e-72 243.0 11.8 2.4 2 0 0 2 2 2 2 G-protein alpha subunit TPR_1 PF00515.28 KER25002.1 - 3.2e-24 83.7 3.8 2.2e-05 24.1 0.8 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KER25002.1 - 7.5e-20 69.4 4.9 0.00045 20.1 0.7 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat Arf PF00025.21 KER25002.1 - 2.9e-13 49.6 0.9 3.8e-10 39.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family TPR_9 PF13371.6 KER25002.1 - 8.5e-11 41.8 4.2 1.2e-05 25.3 1.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER25002.1 - 1.7e-10 40.3 1.2 1.3 9.4 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER25002.1 - 4e-09 36.8 6.3 0.00013 22.4 1.5 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER25002.1 - 2.2e-08 34.3 9.1 0.015 15.5 0.0 4.2 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER25002.1 - 7e-08 33.0 3.2 0.12 13.1 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER25002.1 - 4.8e-07 30.0 1.9 1.4 9.9 0.1 6.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER25002.1 - 8.8e-06 26.0 1.3 0.69 10.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER25002.1 - 3.6e-05 23.5 2.4 4.1 7.6 0.0 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat RPAP3_C PF13877.6 KER25002.1 - 0.00011 22.7 0.0 0.00048 20.6 0.0 2.2 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Gtr1_RagA PF04670.12 KER25002.1 - 0.00022 20.7 1.3 0.00078 18.9 0.1 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TPR_11 PF13414.6 KER25002.1 - 0.00064 19.4 7.2 0.67 9.7 0.0 4.2 5 0 0 5 5 4 2 TPR repeat TPR_17 PF13431.6 KER25002.1 - 0.00077 19.7 14.4 5.3 7.7 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat MMR_HSR1 PF01926.23 KER25002.1 - 0.0078 16.3 0.0 1.1 9.3 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ANAPC3 PF12895.7 KER25002.1 - 0.023 14.9 4.0 0.048 13.9 1.5 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GTP_EFTU PF00009.27 KER25002.1 - 0.037 13.6 0.3 0.7 9.4 0.1 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Fis1_TPR_C PF14853.6 KER25002.1 - 0.039 14.0 6.5 6.5 6.9 0.3 4.2 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SRPRB PF09439.10 KER25002.1 - 0.042 13.3 1.1 2.7 7.4 0.0 3.1 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Ribosomal_L5 PF00281.19 KER25002.1 - 0.043 14.1 0.1 0.24 11.8 0.0 2.3 2 0 0 2 2 1 0 Ribosomal protein L5 HrpA_pilin PF09589.10 KER25002.1 - 0.26 12.0 1.7 0.55 11.0 0.5 2.2 2 0 0 2 2 1 0 HrpA pilus formation protein AA_permease_2 PF13520.6 KER25003.1 - 5.6e-49 167.1 32.6 3e-32 112.0 15.3 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KER25003.1 - 5.8e-20 71.3 34.6 1.1e-15 57.2 19.5 2.3 1 1 1 2 2 2 2 Amino acid permease PLDc_3 PF13918.6 KER25004.1 - 3.4e-38 131.0 0.0 8.1e-38 129.8 0.0 1.6 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.6 KER25004.1 - 1.6e-20 73.3 0.0 3.2e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KER25004.1 - 4.5e-10 39.3 1.9 1.2e-05 25.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Ras PF00071.22 KER25005.1 - 1.4e-56 190.5 0.1 1.8e-56 190.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER25005.1 - 8e-20 71.3 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER25005.1 - 1.6e-08 34.2 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER25005.1 - 0.0041 17.1 0.7 2 8.3 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KER25005.1 - 0.0087 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER25005.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KER25005.1 - 0.019 14.2 0.1 1.6 7.8 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit WRKY PF03106.15 KER25005.1 - 0.2 11.9 2.8 0.44 10.8 0.6 2.5 3 0 0 3 3 3 0 WRKY DNA -binding domain FLYWCH PF04500.16 KER25005.1 - 0.6 10.3 4.1 1.4 9.1 0.8 2.3 2 0 0 2 2 2 0 FLYWCH zinc finger domain Ncstrn_small PF18266.1 KER25006.1 - 9.7e-40 136.3 1.0 2.9e-39 134.8 0.2 2.0 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 KER25006.1 - 6.1e-20 71.7 0.0 9.3e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Nicastrin UCH_C PF18031.1 KER25007.1 - 1.2e-16 60.3 2.9 2.5e-16 59.3 2.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases IES5 PF17335.2 KER25007.1 - 0.012 15.9 0.6 0.021 15.1 0.2 1.6 2 0 0 2 2 2 0 Ino80 complex subunit 5 CHCH PF06747.13 KER25009.1 - 1e-07 31.9 0.3 1.8e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KER25009.1 - 6.9e-05 23.0 0.8 0.00028 21.0 0.2 2.0 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type COX17 PF05051.13 KER25009.1 - 0.028 14.8 1.3 0.048 14.0 0.8 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 KER25009.1 - 0.072 13.3 0.7 2.5 8.4 0.0 2.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Dopey_N PF04118.14 KER25012.1 - 8.9e-91 304.2 0.0 1.5e-89 300.1 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Dscam_C PF12355.8 KER25012.1 - 0.21 12.5 5.6 0.63 11.0 5.6 1.7 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 KER25012.1 - 2.7 7.4 4.1 5.5 6.4 4.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Serinc PF03348.15 KER25013.1 - 1.1e-120 403.5 28.9 2.1e-88 297.1 16.9 2.1 1 1 1 2 2 2 2 Serine incorporator (Serinc) Exo_endo_phos_2 PF14529.6 KER25013.1 - 0.071 12.9 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Actin PF00022.19 KER25014.1 - 1.3e-53 182.1 0.0 4.7e-52 177.0 0.0 2.0 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER25015.1 - 2.4e-207 688.4 0.0 2.8e-109 365.4 0.0 3.5 2 2 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KER25015.1 - 0.023 13.5 0.0 5.9 5.6 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein PilM_2 PF11104.8 KER25015.1 - 0.24 10.4 0.0 4.5 6.2 0.0 2.4 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; APG6 PF04111.12 KER25016.1 - 4.5e-16 59.3 0.1 5.1e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Apg6 BARA domain PDZ PF00595.24 KER25017.1 - 1.5e-55 185.4 0.1 1.5e-12 47.7 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KER25017.1 - 5.6e-23 80.5 5.8 1.1e-05 25.1 0.0 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KER25017.1 - 1.8e-16 60.2 0.3 4e-05 23.8 0.0 4.4 4 0 0 4 4 4 3 PDZ domain zf-RING_UBOX PF13445.6 KER25017.1 - 2.2e-06 27.6 9.3 7.1e-06 26.0 9.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER25017.1 - 6.4e-05 22.7 6.5 6.4e-05 22.7 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER25017.1 - 8.1e-05 22.4 5.9 8.1e-05 22.4 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER25017.1 - 8.2e-05 22.4 11.4 0.00033 20.4 11.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.6 KER25017.1 - 0.00064 19.6 0.4 4.1 7.4 0.0 4.2 4 0 0 4 4 4 1 Tricorn protease PDZ domain zf-RING_5 PF14634.6 KER25017.1 - 0.0014 18.5 8.5 0.0014 18.5 8.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KER25017.1 - 0.003 17.8 8.7 0.003 17.8 8.7 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 KER25017.1 - 0.016 15.3 6.9 0.045 13.9 6.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KER25017.1 - 0.029 14.5 7.6 0.089 12.9 7.6 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KER25017.1 - 0.17 12.2 7.8 0.5 10.7 7.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain PDZ PF00595.24 KER25018.1 - 0.00063 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-TRAF PF02176.18 KER25018.1 - 0.072 13.8 0.7 0.2 12.4 0.7 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger DUF1258 PF06869.12 KER25019.1 - 0.024 14.1 0.1 0.061 12.8 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1258) RVT_1 PF00078.27 KER25020.1 - 4.7e-15 55.7 0.0 7.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4218 PF13960.6 KER25020.1 - 0.0043 16.7 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4806 PF16064.5 KER25020.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DUF3492 PF11997.8 KER25020.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF2457 PF10446.9 KER25020.1 - 2.6 7.1 7.8 3.5 6.7 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) O-FucT PF10250.9 KER25022.1 - 2.8e-07 30.6 0.0 6.8e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Apolipoprotein PF01442.18 KER25022.1 - 0.00027 20.9 2.8 0.0017 18.3 1.3 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain NodZ PF05830.11 KER25022.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) DUF848 PF05852.11 KER25022.1 - 0.035 14.2 0.6 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HJURP_C PF12347.8 KER25022.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat SHIPPO-rpt PF07004.12 KER25025.1 - 0.00082 20.2 5.3 0.0075 17.1 0.3 3.3 3 1 0 3 3 3 2 Sperm-tail PG-rich repeat G-alpha PF00503.20 KER25027.1 - 4.3e-51 174.1 5.1 4.9e-51 174.0 5.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.20 KER25028.1 - 1.3e-50 172.6 0.1 1.8e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER25028.1 - 0.00025 20.6 1.1 0.051 13.0 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Rad17 PF03215.15 KER25028.1 - 0.0022 17.9 0.2 0.0043 17.0 0.2 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DAP3 PF10236.9 KER25028.1 - 0.0061 15.8 0.4 0.011 14.9 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 KER25028.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_S17 PF00366.20 KER25029.1 - 5.6e-26 90.4 5.1 8.6e-26 89.8 5.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KER25029.1 - 3.4e-23 81.8 5.2 3.4e-23 81.8 5.2 2.4 2 1 0 2 2 2 1 Ribosomal_S17 N-terminal PRF PF06875.11 KER25029.1 - 0.037 13.5 0.4 0.056 12.9 0.4 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF DUF3954 PF13128.6 KER25031.1 - 0.012 15.4 0.6 6.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) UCH_N PF16674.5 KER25031.1 - 0.096 12.6 0.0 18 5.3 0.0 2.2 2 0 0 2 2 2 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 DUF2590 PF10761.9 KER25031.1 - 0.12 12.5 0.1 14 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Chromo_shadow PF01393.19 KER25033.1 - 9.1e-30 102.5 0.1 1.4e-28 98.7 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 KER25033.1 - 1.6e-21 76.0 1.0 1.5e-18 66.4 0.9 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SRP-alpha_N PF04086.13 KER25033.1 - 3.7 7.4 8.1 7.4 6.4 8.1 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mcm10 PF09332.11 KER25034.1 - 2e-62 211.7 2.1 2e-62 211.7 2.1 2.9 2 1 1 3 3 3 2 Mcm10 replication factor zf-primase PF09329.11 KER25034.1 - 3e-13 49.3 1.1 3e-13 49.3 1.1 2.0 2 0 0 2 2 2 1 Primase zinc finger Ribosomal_S27e PF01667.17 KER25034.1 - 0.00062 19.4 0.7 0.00062 19.4 0.7 2.1 2 0 0 2 2 2 1 Ribosomal protein S27 Bd3614-deam PF14439.6 KER25034.1 - 1.1 9.4 4.0 6 6.9 0.8 2.6 2 0 0 2 2 2 0 Bd3614-like deaminase PSP PF04046.16 KER25036.1 - 7.4e-15 54.5 0.2 1.3e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 PSP SnAPC_2_like PF11035.8 KER25036.1 - 5.8 7.0 7.0 1.4 9.0 0.3 2.2 1 1 1 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb zf-RING_2 PF13639.6 KER25038.1 - 8.7e-11 42.0 9.7 8.7e-11 42.0 9.7 2.9 2 1 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 KER25038.1 - 4.1e-09 36.6 7.1 1.4e-08 34.8 7.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER25038.1 - 2.6e-08 33.7 7.3 9.5e-08 31.9 7.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KER25038.1 - 1.3e-06 28.1 10.3 1.3e-06 28.1 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER25038.1 - 4.9e-06 26.3 7.9 4.9e-06 26.3 7.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER25038.1 - 5.6e-05 23.0 8.4 5.6e-05 23.0 8.4 2.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KER25038.1 - 5.8e-05 23.1 5.0 0.00015 21.8 5.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KER25038.1 - 8.3e-05 22.2 8.0 0.00026 20.6 8.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KER25038.1 - 0.00021 21.1 7.3 0.00021 21.1 7.3 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER25038.1 - 0.0011 18.8 9.0 0.058 13.3 9.2 2.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KER25038.1 - 0.0037 17.5 9.1 0.0037 17.5 9.1 2.3 2 0 0 2 2 2 1 RING-like domain Zn_ribbon_17 PF17120.5 KER25038.1 - 0.0061 16.2 8.0 0.022 14.4 8.0 2.0 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rx_N PF18052.1 KER25038.1 - 0.039 14.2 1.1 0.039 14.2 1.1 3.2 2 2 2 4 4 4 0 Rx N-terminal domain Zn-ribbon_8 PF09723.10 KER25038.1 - 0.091 12.9 3.3 1.7 8.8 1.2 2.9 2 0 0 2 2 2 0 Zinc ribbon domain HrpB2 PF09487.10 KER25038.1 - 0.21 12.0 9.0 0.52 10.7 0.7 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Prok-RING_1 PF14446.6 KER25038.1 - 0.47 10.4 13.0 0.057 13.4 6.0 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KER25038.1 - 0.67 10.2 9.4 0.36 11.0 5.3 2.7 2 1 1 3 3 3 0 FANCL C-terminal domain BST2 PF16716.5 KER25038.1 - 0.89 10.2 15.5 0.66 10.6 6.8 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 KER25038.1 - 1.2 10.1 22.5 7.1 7.6 2.4 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Glycohydro_20b2 PF14845.6 KER25038.1 - 1.7 9.3 5.7 27 5.4 1.3 2.5 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like 6PGD PF00393.19 KER25040.1 - 6.3e-125 416.3 0.0 8e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KER25040.1 - 5.1e-51 173.0 0.0 9.1e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KER25040.1 - 5.6e-05 23.2 0.2 0.00015 21.8 0.2 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KER25040.1 - 0.0064 17.0 0.2 0.012 16.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KER25040.1 - 0.013 15.7 0.1 0.076 13.3 0.0 2.3 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KER25040.1 - 0.064 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KER25040.1 - 0.069 12.7 0.0 0.62 9.6 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DNA_pol3_beta PF00712.19 KER25040.1 - 0.12 12.5 0.1 0.4 10.8 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain ApbA PF02558.16 KER25040.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIA_gamma_C PF02751.14 KER25041.1 - 2.3e-21 75.7 0.4 3.7e-21 75.0 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KER25041.1 - 1.4e-18 66.6 0.4 2.1e-18 66.1 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF3886 PF13025.6 KER25041.1 - 0.069 13.3 0.8 0.15 12.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) TBPIP PF07106.13 KER25041.1 - 0.11 12.5 0.4 2 8.4 0.1 2.3 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain zf-H2C2_2 PF13465.6 KER25042.1 - 0.0054 17.1 2.4 0.0054 17.1 2.4 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KER25042.1 - 0.019 15.4 6.4 0.4 11.2 0.3 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER25042.1 - 0.028 15.2 9.4 0.26 12.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger EGF_3 PF12947.7 KER25042.1 - 0.074 13.3 1.9 0.17 12.1 1.9 1.6 1 0 0 1 1 1 0 EGF domain BolA PF01722.18 KER25042.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 BolA-like protein zf-met PF12874.7 KER25042.1 - 0.65 10.5 9.2 4.4 7.8 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER25042.1 - 0.74 9.9 9.5 9.2 6.4 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KER25042.1 - 0.85 9.3 8.9 6.1 6.6 0.3 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 KER25042.1 - 2 8.2 5.7 0.64 9.8 0.5 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KER25042.1 - 2.8 8.3 6.5 2.6 8.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SNF PF00209.18 KER25043.1 - 3.6e-07 29.3 7.0 4.8e-07 28.9 7.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Herpes_US9 PF06072.11 KER25043.1 - 0.019 14.8 0.7 0.088 12.7 0.7 2.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4231 PF14015.6 KER25043.1 - 0.31 11.5 1.9 6.2 7.4 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) DUF3112 PF11309.8 KER25043.1 - 0.36 10.3 7.0 0.098 12.1 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) GWT1 PF06423.12 KER25043.1 - 1.6 8.8 6.9 1.4 9.0 0.3 2.7 1 1 0 2 2 2 0 GWT1 AC_N PF16214.5 KER25043.1 - 3.3 6.7 10.5 3.3 6.7 9.2 1.6 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region SNARE PF05739.19 KER25043.1 - 6.7 6.8 8.3 0.89 9.6 0.1 3.0 3 0 0 3 3 3 0 SNARE domain RRM_1 PF00076.22 KER25044.1 - 2.2e-10 40.2 0.0 3.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KER25046.1 - 2.1e-14 53.5 0.0 3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER25046.1 - 8.8e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Cpn60_TCP1 PF00118.24 KER25047.1 - 1.5e-78 264.6 9.3 3.2e-78 263.5 9.3 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KER25048.1 - 1.1e-45 156.1 0.0 4.9e-42 144.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER25048.1 - 3.8e-29 101.8 0.0 8.2e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER25048.1 - 0.00024 20.0 0.0 0.00055 18.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER25048.1 - 0.0016 17.8 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DUF4359 PF14271.6 KER25048.1 - 0.13 13.1 0.1 0.35 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) DUF316 PF03761.15 KER25049.1 - 0.072 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Aldedh PF00171.22 KER25050.1 - 1.9e-95 320.1 0.1 1.8e-46 158.7 0.0 3.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family Lantibiotic_a PF14867.6 KER25050.1 - 0.12 12.1 1.1 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Lantibiotic alpha NMT1 PF09084.11 KER25050.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like Flu_C_NS2 PF03555.14 KER25052.1 - 0.097 12.9 0.1 23 5.3 0.0 2.3 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) Clr2_transil PF16761.5 KER25052.1 - 0.49 11.3 3.1 13 6.7 0.1 2.6 2 1 1 3 3 3 0 Transcription-silencing protein, cryptic loci regulator Clr2 HPD PF05044.12 KER25055.1 - 5.7e-80 266.6 4.4 7e-80 266.3 4.4 1.1 1 0 0 1 1 1 1 Homeo-prospero domain PAP_PilO PF06864.12 KER25055.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2974 PF11187.8 KER25056.1 - 0.0019 17.8 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) zf-C2H2 PF00096.26 KER25057.1 - 2e-31 106.7 80.1 3.9e-05 23.9 2.0 9.2 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER25057.1 - 1.8e-20 71.9 77.6 0.0025 18.5 2.4 9.1 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER25057.1 - 9.5e-15 54.3 69.2 0.033 14.6 2.2 10.2 9 2 0 9 9 9 7 Zinc-finger double domain zf-Di19 PF05605.12 KER25057.1 - 4e-12 46.2 44.6 0.00049 20.3 5.7 5.4 5 0 0 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KER25057.1 - 6.5e-12 45.1 8.5 0.025 14.4 0.2 5.8 5 0 0 5 5 5 3 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KER25057.1 - 3.8e-10 39.5 57.8 0.039 14.0 0.9 9.2 9 0 0 9 9 9 6 C2H2-type zinc finger TFIIS_C PF01096.18 KER25057.1 - 1.7e-05 24.6 28.6 0.059 13.2 0.3 6.8 7 0 0 7 7 7 2 Transcription factor S-II (TFIIS) IBB PF01749.20 KER25057.1 - 2.4e-05 24.7 1.2 0.33 11.4 0.1 2.5 2 0 0 2 2 2 2 Importin beta binding domain zinc_ribbon_15 PF17032.5 KER25057.1 - 0.00017 22.3 30.8 1.3 9.9 0.5 5.2 2 1 3 5 5 5 2 zinc-ribbon family zf-C2HC_2 PF13913.6 KER25057.1 - 0.00018 21.3 50.3 0.036 14.0 1.2 7.2 7 0 0 7 7 7 4 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KER25057.1 - 0.0007 19.3 1.3 0.064 13.0 0.1 7.7 8 0 0 8 8 8 2 zinc-finger C2H2-type Desulfoferrod_N PF06397.12 KER25057.1 - 0.0013 18.3 9.6 4.5 7.0 0.1 5.4 5 0 0 5 5 5 2 Desulfoferrodoxin, N-terminal domain zf-C2H2_3rep PF18868.1 KER25057.1 - 0.0046 17.6 25.8 1.4 9.6 2.7 6.0 1 1 4 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KER25057.1 - 0.0056 16.2 0.9 0.2 11.3 0.1 8.5 9 0 0 9 9 9 2 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 KER25057.1 - 0.009 15.6 18.9 2.4 7.9 0.8 5.2 4 1 1 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain Nop10p PF04135.12 KER25057.1 - 0.0091 16.0 7.5 19 5.4 0.0 5.7 5 0 0 5 5 5 0 Nucleolar RNA-binding protein, Nop10p family Actin_micro PF17003.5 KER25057.1 - 0.012 14.8 23.7 0.11 11.6 3.0 4.1 2 2 2 4 4 4 0 Putative actin-like family Ribosomal_L26 PF16906.5 KER25057.1 - 0.023 15.2 2.2 5.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF4207 PF13904.6 KER25057.1 - 0.024 14.4 7.6 0.99 9.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) zf-ribbon_3 PF13248.6 KER25057.1 - 0.031 13.7 23.7 2.4 7.7 0.4 5.9 5 0 0 5 5 5 0 zinc-ribbon domain DUF1610 PF07754.11 KER25057.1 - 0.065 13.2 30.9 0.45 10.5 0.6 6.8 7 0 0 7 7 7 0 Domain of unknown function (DUF1610) zf-C2H2_2 PF12756.7 KER25057.1 - 0.16 12.3 46.3 0.87 10.0 3.7 7.1 2 2 5 7 7 7 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 KER25057.1 - 0.2 11.8 48.2 2 8.6 3.5 7.3 4 4 4 9 9 9 0 Zinc ribbon domain PSRT PF07636.11 KER25057.1 - 0.26 11.0 2.8 21 4.9 0.0 3.2 2 1 0 2 2 2 0 PSRT Zn_Tnp_IS1595 PF12760.7 KER25057.1 - 0.27 11.2 53.1 0.23 11.4 5.4 6.0 5 2 0 5 5 5 0 Transposase zinc-ribbon domain PIN_11 PF18479.1 KER25057.1 - 0.38 10.9 3.3 18 5.5 0.2 2.5 2 0 0 2 2 2 0 PIN like domain TerY_C PF15616.6 KER25057.1 - 0.67 10.1 26.2 0.98 9.5 1.1 5.0 2 2 2 5 5 5 0 TerY-C metal binding domain DUF3839 PF12943.7 KER25057.1 - 0.87 9.0 4.5 12 5.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) ADK_lid PF05191.14 KER25057.1 - 1 9.4 28.6 2.8 8.0 0.8 5.6 4 1 0 5 5 5 0 Adenylate kinase, active site lid zf-CHCC PF10276.9 KER25057.1 - 1.3 9.2 12.3 41 4.4 0.1 5.5 5 0 0 5 5 5 0 Zinc-finger domain zf-FPG_IleRS PF06827.14 KER25057.1 - 1.5 8.8 34.0 2.6 8.0 0.7 6.7 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS zf-met PF12874.7 KER25057.1 - 1.5 9.3 43.5 0.12 12.8 3.0 7.3 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-NADH-PPase PF09297.11 KER25057.1 - 2.8 7.7 16.8 11 5.8 0.0 5.6 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_SprT PF17283.2 KER25057.1 - 4.5 7.3 48.3 0.25 11.3 6.3 6.5 5 4 2 7 7 7 0 SprT-like zinc ribbon domain DUF629 PF04780.12 KER25057.1 - 6.9 5.1 30.4 0.072 11.6 1.5 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF629) Endostatin PF06482.11 KER25059.1 - 2.5e-07 30.5 0.2 5.8e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Collagenase NC10 and Endostatin Collagen PF01391.18 KER25059.1 - 0.29 10.9 19.7 0.27 11.0 0.5 2.7 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) PEX11 PF05648.14 KER25059.1 - 0.31 10.5 3.9 0.52 9.7 3.9 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Kinesin PF00225.23 KER25060.1 - 3.5e-46 157.7 0.2 6.1e-46 156.9 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER25060.1 - 6.3e-25 87.9 2.0 8.8e-25 87.4 0.1 2.2 3 1 0 3 3 3 1 Microtubule binding AAA_17 PF13207.6 KER25060.1 - 0.015 15.7 0.5 0.33 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3592 PF12158.8 KER25060.1 - 0.063 13.3 0.5 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) SRP9-21 PF05486.12 KER25060.1 - 0.39 11.1 3.9 1.3 9.4 3.9 2.0 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF4472 PF14739.6 KER25060.1 - 0.54 11.0 17.8 2 9.2 5.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Atg14 PF10186.9 KER25060.1 - 0.95 8.5 17.4 1.7 7.7 17.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PP2C_2 PF13672.6 KER25063.1 - 0.22 11.1 0.0 0.23 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C dNK PF01712.19 KER25065.1 - 1.6e-20 73.8 0.4 3.6e-20 72.7 0.0 1.8 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 KER25065.1 - 0.0018 18.6 0.0 0.39 10.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KER25065.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KER25065.1 - 0.017 15.5 0.0 0.098 13.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KER25065.1 - 0.022 15.3 0.0 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KER25065.1 - 0.027 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KER25065.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KER25065.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KER25065.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KER25065.1 - 0.082 13.3 0.0 4.3 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KER25065.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-C4 PF00105.18 KER25066.1 - 1.4e-27 96.0 15.9 1.4e-27 96.0 15.9 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 KER25066.1 - 1.9 8.6 8.5 6.3 7.0 8.5 1.9 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type RseA_C PF03873.13 KER25068.1 - 0.39 11.0 24.0 4.1 7.7 0.0 9.2 9 0 0 9 9 9 0 Anti sigma-E protein RseA, C-terminal domain DUF4512 PF14975.6 KER25069.1 - 0.002 18.9 12.6 0.022 15.5 12.6 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) Cwf_Cwc_15 PF04889.12 KER25070.1 - 0.058 13.1 3.8 0.073 12.8 3.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.26 KER25071.1 - 6.9e-28 95.5 53.9 4.7e-05 23.6 3.0 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER25071.1 - 1.2e-16 59.9 49.2 0.0034 18.1 1.6 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER25071.1 - 1.8e-10 40.7 46.9 0.00043 20.6 3.1 8.7 8 1 0 8 8 8 3 Zinc-finger double domain zf-met PF12874.7 KER25071.1 - 3.2e-09 36.8 20.7 0.029 14.8 0.3 5.6 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER25071.1 - 5.8e-08 32.8 24.3 0.038 14.3 0.1 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KER25071.1 - 3.6e-07 30.4 28.8 0.0009 19.5 4.9 4.3 3 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KER25071.1 - 8.9e-06 25.7 16.9 0.88 9.7 0.0 5.2 3 2 2 5 5 5 2 Zinc ribbon domain Rad50_zn_hook PF04423.14 KER25071.1 - 9.8e-06 25.3 1.7 1.2 9.1 0.0 3.6 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-C2H2_11 PF16622.5 KER25071.1 - 0.00024 20.8 3.2 0.016 15.0 0.3 5.5 6 0 0 6 6 4 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KER25071.1 - 0.00088 18.8 24.2 1.8 8.2 0.3 5.9 6 0 0 6 6 6 4 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 KER25071.1 - 0.0012 18.9 18.7 0.74 9.9 0.2 5.1 1 1 4 5 5 5 2 CpXC protein zf-C2HC_2 PF13913.6 KER25071.1 - 0.0013 18.6 5.6 0.028 14.3 0.5 5.9 6 0 0 6 6 6 2 zinc-finger of a C2HC-type FdhE PF04216.12 KER25071.1 - 0.0013 18.7 0.9 0.048 13.5 0.3 2.4 2 0 0 2 2 2 1 Protein involved in formate dehydrogenase formation Vps36-NZF-N PF16988.5 KER25071.1 - 0.0015 17.9 2.4 4.1 6.9 0.1 4.4 4 0 0 4 4 4 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_6 PF13912.6 KER25071.1 - 0.002 18.1 34.4 1.2 9.2 3.1 5.8 6 0 0 6 6 5 4 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KER25071.1 - 0.0036 17.7 15.5 2.1 8.9 0.6 5.1 5 0 0 5 5 4 2 Autophagy receptor zinc finger-C2H2 domain zf-DNA_Pol PF08996.10 KER25071.1 - 0.0058 16.4 8.5 0.95 9.2 0.4 3.3 3 0 0 3 3 3 1 DNA Polymerase alpha zinc finger zinc_ribbon_15 PF17032.5 KER25071.1 - 0.011 16.5 13.4 1.7 9.4 0.1 4.1 2 1 2 4 4 4 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 KER25071.1 - 0.016 15.1 23.2 0.88 9.5 0.6 5.0 3 2 2 5 5 5 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 KER25071.1 - 0.047 13.6 11.9 33 4.5 0.0 5.7 5 1 0 5 5 5 0 Prokaryotic RING finger family 1 DUF5420 PF17457.2 KER25071.1 - 0.047 13.6 0.2 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5420) Lbh PF15317.6 KER25071.1 - 0.06 14.2 0.1 23 5.9 0.0 2.7 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein zf-H2C2_5 PF13909.6 KER25071.1 - 0.071 12.9 0.1 0.071 12.9 0.1 5.7 6 0 0 6 6 6 0 C2H2-type zinc-finger domain Actin_micro PF17003.5 KER25071.1 - 0.1 11.8 13.4 7e+02 -0.9 13.4 3.8 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_3rep PF18868.1 KER25071.1 - 0.11 13.2 19.3 16 6.2 8.3 4.8 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 KER25071.1 - 0.13 12.6 15.8 11 6.4 0.1 5.3 6 0 0 6 6 5 0 zinc-ribbon zf_C2H2_ZHX PF18387.1 KER25071.1 - 0.17 11.6 16.9 0.3 10.8 0.2 4.7 3 1 2 5 5 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Desulfoferrod_N PF06397.12 KER25071.1 - 0.27 10.9 16.2 8.3 6.1 0.2 5.2 6 0 0 6 6 6 0 Desulfoferrodoxin, N-terminal domain zf_C2H2_13 PF18508.1 KER25071.1 - 0.31 10.6 7.6 18 5.0 0.0 4.1 4 0 0 4 4 3 0 Zinc finger domain zf-MYST PF17772.1 KER25071.1 - 0.33 10.6 16.3 3.8 7.2 0.0 4.8 4 2 2 6 6 6 0 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KER25071.1 - 0.41 11.0 15.7 0.21 11.9 0.7 3.7 3 1 1 4 4 4 0 C2H2-type zinc ribbon FAM217 PF15344.6 KER25071.1 - 0.63 9.9 11.0 1.5 8.7 4.3 2.4 1 1 2 3 3 3 0 FAM217 family C1_4 PF07975.12 KER25071.1 - 0.77 10.0 14.8 40 4.5 0.8 5.0 3 3 2 5 5 5 0 TFIIH C1-like domain Sgf11 PF08209.11 KER25071.1 - 0.94 9.1 15.5 24 4.6 0.1 5.9 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) BolA PF01722.18 KER25071.1 - 1.4 9.2 7.2 5.9 7.2 1.9 3.4 3 1 0 3 3 3 0 BolA-like protein A2L_zn_ribbon PF08792.10 KER25071.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.7 5 0 0 5 5 3 0 A2L zinc ribbon domain DUF1610 PF07754.11 KER25071.1 - 2.3 8.3 8.8 9.7 6.3 1.5 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) Trm112p PF03966.16 KER25071.1 - 4.9 7.8 5.7 6.7 7.4 0.3 3.6 4 2 0 4 4 4 0 Trm112p-like protein DUF2256 PF10013.9 KER25071.1 - 6.6 6.9 14.2 34 4.7 0.3 4.7 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Lar_restr_allev PF14354.6 KER25071.1 - 8.1 6.9 19.4 2.9 8.3 0.4 4.5 3 1 1 4 4 4 0 Restriction alleviation protein Lar JAMP PF05571.12 KER25072.1 - 1.2e-30 107.2 33.7 1.4e-18 67.5 25.0 2.5 2 1 0 2 2 2 2 JNK1/MAPK8-associated membrane protein COX7a PF02238.15 KER25072.1 - 0.57 10.6 2.4 2.8 8.4 2.4 2.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII MRAP PF15183.6 KER25072.1 - 0.9 9.5 4.1 17 5.4 0.2 2.8 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family SH3_1 PF00018.28 KER25073.1 - 1.2e-16 60.0 0.1 2.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain VHS PF00790.19 KER25073.1 - 2.8e-16 59.6 0.1 4.7e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.6 KER25073.1 - 1.7e-12 47.0 0.1 3.5e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER25073.1 - 3.4e-12 45.9 0.0 5.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KER25073.1 - 0.001 18.8 1.2 0.001 18.8 1.2 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif SH3_10 PF17902.1 KER25073.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PTB PF08416.13 KER25074.1 - 4.7e-07 30.0 0.0 8.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 KER25074.1 - 0.00017 21.6 0.0 0.00044 20.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain DUF4835 PF16119.5 KER25074.1 - 0.053 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Granulin PF00396.18 KER25075.1 - 2.4e-13 50.2 21.2 2.4e-13 50.2 21.2 2.1 2 0 0 2 2 2 1 Granulin DUF4013 PF13197.6 KER25075.1 - 0.047 13.5 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Serpin PF00079.20 KER25076.1 - 5.1e-150 499.9 0.0 8.4e-71 239.2 0.0 3.0 2 1 1 3 3 3 3 Serpin (serine protease inhibitor) Fzo_mitofusin PF04799.13 KER25076.1 - 0.073 12.6 1.3 5 6.7 0.1 2.3 2 0 0 2 2 2 0 fzo-like conserved region DUF4371 PF14291.6 KER25076.1 - 0.098 12.3 0.0 35 3.9 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4371) Serpin PF00079.20 KER25077.1 - 4.2e-13 49.3 0.0 1.3e-12 47.7 0.0 1.7 1 1 1 2 2 2 1 Serpin (serine protease inhibitor) zf-C2H2 PF00096.26 KER25080.1 - 5.4e-17 61.2 35.1 0.0012 19.1 0.4 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER25080.1 - 1.6e-15 56.4 33.0 0.0022 18.7 0.1 5.9 6 0 0 6 6 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER25080.1 - 5e-09 36.2 28.8 0.0019 18.5 0.4 7.4 7 1 0 7 7 7 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 KER25080.1 - 1.1e-06 28.3 24.5 0.017 14.8 0.1 5.3 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KER25080.1 - 0.0074 17.0 14.6 1.3 9.7 0.9 3.8 1 1 3 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KER25080.1 - 0.008 16.5 18.9 0.059 13.8 0.6 4.9 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KER25080.1 - 0.0097 15.5 14.6 0.2 11.3 0.3 4.5 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 KER25080.1 - 0.0097 15.9 26.6 0.17 11.9 0.2 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KER25080.1 - 0.065 13.0 0.7 0.065 13.0 0.7 6.2 6 1 0 6 6 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KER25080.1 - 0.073 13.4 24.1 0.66 10.3 0.8 4.4 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KER25080.1 - 0.17 11.8 0.3 0.17 11.8 0.3 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KER25080.1 - 0.43 10.7 21.1 3.2 7.9 3.9 4.6 2 2 3 5 5 5 0 Zinc ribbon domain ADK_lid PF05191.14 KER25080.1 - 0.59 10.2 10.1 2.4 8.2 0.0 4.3 3 2 4 7 7 7 0 Adenylate kinase, active site lid HypA PF01155.19 KER25080.1 - 0.63 10.1 11.9 5.4 7.1 2.4 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 KER25080.1 - 0.93 9.9 22.9 0.64 10.4 0.2 5.0 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KER25080.1 - 1.7 8.6 17.8 20 5.2 2.8 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type ROS_MUCR PF05443.11 KER25080.1 - 2.5 8.2 6.8 43 4.2 0.1 3.9 1 1 2 4 4 4 0 ROS/MUCR transcriptional regulator protein Elf1 PF05129.13 KER25080.1 - 3 7.9 13.0 3.3 7.8 0.3 3.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 KER25080.1 - 8.7 6.5 22.8 6.3 6.9 10.7 3.4 1 1 1 2 2 2 0 Double zinc ribbon Calcipressin PF04847.12 KER25081.1 - 1.4e-05 25.0 1.2 2.1e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 Calcipressin Piwi PF02171.17 KER25085.1 - 3.5e-143 476.3 0.0 4e-84 282.4 0.0 2.1 1 1 1 2 2 2 2 Piwi domain PAZ PF02170.22 KER25085.1 - 8.5e-11 41.8 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KER25085.1 - 3.1e-07 30.6 0.1 1.8e-06 28.2 0.0 2.4 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KER25085.1 - 4.7e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KER25085.1 - 0.00013 22.5 0.1 0.00055 20.6 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of argonaute Vip3A_N PF12495.8 KER25085.1 - 0.025 14.5 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal Transket_pyr PF02779.24 KER25085.1 - 0.16 11.7 0.0 23 4.6 0.0 2.3 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain RhoGEF PF00621.20 KER25087.1 - 8.6e-35 120.6 3.3 8.6e-35 120.6 3.3 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 KER25087.1 - 5.2e-29 100.6 0.1 5e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER25087.1 - 1.9e-17 62.8 1.5 2.2e-07 30.6 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain UPF0300 PF08594.10 KER25087.1 - 3.9e-05 23.1 0.0 0.48 9.7 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0300) KxDL PF10241.9 KER25087.1 - 0.29 11.4 2.2 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein HhH-GPD PF00730.25 KER25088.1 - 4.7e-17 62.4 0.0 8.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SH2 PF00017.24 KER25088.1 - 1.7e-13 50.5 0.0 4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KER25088.1 - 4.7e-11 42.1 0.8 1.6e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KER25088.1 - 2.4e-10 39.9 0.1 0.0011 18.6 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KER25088.1 - 2.5e-09 36.9 0.9 0.00016 21.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KER25088.1 - 4.4e-09 36.1 2.6 1.8e-08 34.2 2.6 2.0 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 KER25088.1 - 1.7e-08 34.9 0.0 3.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 PH domain HHH PF00633.23 KER25088.1 - 2.4e-08 33.5 0.0 6.2e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif C1_2 PF03107.16 KER25088.1 - 0.15 12.4 4.0 0.51 10.7 4.0 2.0 1 0 0 1 1 1 0 C1 domain Secretogranin_V PF05281.11 KER25089.1 - 5.1e-20 72.1 4.6 3.7e-19 69.3 4.6 2.0 1 1 0 1 1 1 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) Intg_mem_TP0381 PF09529.10 KER25092.1 - 0.041 13.4 0.6 6.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) PIG-P PF08510.12 KER25092.1 - 0.068 13.1 3.2 6.5 6.7 0.3 2.3 2 0 0 2 2 2 0 PIG-P DUF2418 PF10332.9 KER25092.1 - 0.11 13.1 3.3 9.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Mu-conotoxin PF05374.12 KER25092.1 - 0.31 11.1 2.6 16 5.6 0.2 2.2 2 0 0 2 2 2 0 Mu-Conotoxin HABP4_PAI-RBP1 PF04774.15 KER25094.1 - 1e-06 29.6 5.9 1e-06 29.6 5.9 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family HSP20 PF00011.21 KER25095.1 - 3.1e-23 81.8 0.1 1.6e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KER25095.1 - 1.7e-05 24.2 0.0 0.00057 19.4 0.0 2.4 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Sushi PF00084.20 KER25096.1 - 2.3e-36 124.2 24.9 1.5e-10 41.5 0.4 7.3 8 0 0 8 8 8 6 Sushi repeat (SCR repeat) Glypican PF01153.19 KER25098.1 - 1.8e-16 60.1 0.1 5e-16 58.7 0.1 1.5 1 1 0 1 1 1 1 Glypican Taeniidae_ag PF05596.11 KER25098.1 - 0.022 14.7 0.9 0.06 13.3 0.0 2.0 3 0 0 3 3 3 0 Taeniidae antigen PRA-PH PF01503.17 KER25098.1 - 0.21 12.1 0.2 0.45 11.0 0.2 1.4 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Exo_endo_phos_2 PF14529.6 KER25099.1 - 9.2e-05 22.3 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ThiF PF00899.21 KER25101.1 - 5.7e-75 251.8 0.0 8e-38 130.2 0.0 3.8 2 1 1 3 3 3 3 ThiF family UBA_e1_thiolCys PF10585.9 KER25101.1 - 1e-55 189.4 0.0 1.7e-55 188.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 KER25101.1 - 1.4e-12 47.6 0.3 4.1e-12 46.1 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 KER25101.1 - 9.2e-12 45.0 0.1 4e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KER25101.1 - 2.4e-08 34.5 0.0 5.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Defensin_4 PF07936.12 KER25109.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Potassium-channel blocking toxin EF-hand_1 PF00036.32 KER25111.1 - 6.5e-37 122.3 11.9 2.2e-09 36.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER25111.1 - 3.1e-32 110.9 2.9 6e-15 55.4 1.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KER25111.1 - 7.8e-29 99.3 10.0 9.8e-13 47.7 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KER25111.1 - 1.1e-25 87.3 7.9 3.7e-09 35.8 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KER25111.1 - 1.6e-23 81.1 9.4 2e-06 27.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KER25111.1 - 1.8e-12 47.4 0.1 9.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KER25111.1 - 5.1e-07 29.6 0.3 0.034 14.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER25111.1 - 7.3e-06 26.3 0.0 0.14 12.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KER25111.1 - 0.0002 21.3 0.0 0.12 12.4 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KER25111.1 - 0.00038 21.3 0.0 0.064 14.1 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 KER25111.1 - 0.00086 19.4 0.2 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 KER25111.1 - 0.0062 16.7 4.5 0.27 11.4 0.5 2.9 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 KER25111.1 - 0.019 15.0 0.2 2.2 8.2 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF1103 PF06513.11 KER25111.1 - 0.023 14.3 2.1 0.032 13.9 2.1 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Caleosin PF05042.13 KER25111.1 - 0.023 14.6 0.2 1.4 8.8 0.0 2.9 1 1 2 3 3 3 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KER25111.1 - 0.024 15.0 0.5 4.4 7.7 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF4497 PF14924.6 KER25111.1 - 0.029 14.8 0.0 6.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) DUF3349 PF11829.8 KER25111.1 - 0.033 15.0 0.3 8.9 7.2 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.10 KER25111.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.16 KER25111.1 - 0.14 12.4 0.0 3 8.1 0.0 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein dCache_2 PF08269.11 KER25111.1 - 0.19 10.9 0.1 5 6.2 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 KER25111.1 - 0.21 11.3 0.4 0.75 9.4 0.4 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CK_II_beta PF01214.18 KER25113.1 - 9.4e-82 273.2 0.1 1.1e-81 273.0 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1375 PF07119.12 KER25114.1 - 0.08 13.3 0.7 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) DUF1189 PF06691.11 KER25114.1 - 0.096 12.2 0.6 0.13 11.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) LSM PF01423.22 KER25115.1 - 1.7e-15 56.5 0.0 1.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KER25115.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein bZIP_2 PF07716.15 KER25121.1 - 5.4e-24 84.0 30.2 7.4e-16 58.0 10.1 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KER25121.1 - 2e-06 27.8 29.1 0.00029 20.9 9.9 2.4 2 0 0 2 2 2 2 bZIP transcription factor HALZ PF02183.18 KER25121.1 - 0.53 10.5 3.9 22 5.4 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phlebovirus_NSM PF07246.11 KER25121.1 - 6.6 6.0 10.3 4.6 6.5 2.3 2.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.9 KER25121.1 - 9.7 6.2 10.5 2.5 8.1 2.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2724 PF10893.8 KER25123.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) ATP-synt_ab PF00006.25 KER25124.1 - 2.7e-105 350.7 0.0 4e-105 350.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KER25124.1 - 5.3e-43 145.7 0.0 9.5e-43 144.9 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Tektin PF03148.14 KER25125.1 - 9.6e-116 386.7 37.3 1.2e-115 386.4 37.3 1.0 1 0 0 1 1 1 1 Tektin family CG-1 PF03859.16 KER25125.1 - 0.091 12.6 1.0 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 CG-1 domain Goodbye PF17109.5 KER25125.1 - 0.4 11.1 2.8 2.7 8.5 0.0 3.1 2 2 2 4 4 4 0 fungal STAND N-terminal Goodbye domain FmiP_Thoc5 PF09766.9 KER25125.1 - 1.5 8.0 18.2 0.49 9.6 1.8 2.8 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 DUF3584 PF12128.8 KER25125.1 - 2.3 5.6 38.2 0.16 9.5 8.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KER25125.1 - 3 7.9 18.7 0.53 10.3 0.2 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KER25125.1 - 3.7 7.6 26.3 0.16 12.1 1.6 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KER25125.1 - 4.4 7.6 27.4 1.3 9.3 0.6 4.1 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KER25125.1 - 7.3 7.1 15.3 0.1 13.0 2.2 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) EF-hand_7 PF13499.6 KER25126.1 - 2.8e-25 88.5 0.3 6e-11 42.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KER25126.1 - 3.3e-25 85.7 2.5 6.5e-06 25.3 0.0 5.3 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KER25126.1 - 5.5e-24 82.0 0.1 2.4e-06 27.0 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KER25126.1 - 1.4e-15 56.9 4.8 1.4e-06 28.0 0.0 5.0 3 3 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KER25126.1 - 3e-14 51.7 0.1 0.00036 19.9 0.0 4.1 5 0 0 5 5 5 3 EF hand HipA_C PF07804.12 KER25126.1 - 0.00087 19.0 0.4 0.26 10.9 0.2 2.1 1 1 1 2 2 2 2 HipA-like C-terminal domain EF-hand_10 PF14788.6 KER25126.1 - 0.012 15.4 0.1 0.28 11.1 0.0 2.5 2 1 0 2 2 2 0 EF hand EAP30 PF04157.16 KER25126.1 - 0.059 12.7 0.0 0.76 9.0 0.0 2.1 1 1 0 1 1 1 0 EAP30/Vps36 family HTH_Tnp_Tc3_2 PF01498.18 KER25126.1 - 0.07 13.4 0.0 10 6.4 0.0 2.1 2 0 0 2 2 2 0 Transposase EF-hand_13 PF17958.1 KER25126.1 - 0.12 12.2 0.0 21 5.0 0.0 3.2 2 1 2 4 4 4 0 EF-hand domain RloB PF13707.6 KER25126.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 RloB-like protein DUF3421 PF11901.8 KER25128.1 - 2.8e-31 107.9 0.0 1.1e-30 106.0 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3421) EIAV_GP90 PF00971.18 KER25130.1 - 0.12 11.0 0.3 21 3.7 0.0 2.8 3 0 0 3 3 3 0 EIAV coat protein, gp90 PFL-like PF02901.15 KER25132.1 - 0.06 12.0 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like DAGK_cat PF00781.24 KER25134.1 - 7.5e-27 93.4 0.0 1.9e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 KER25134.1 - 2e-19 70.5 0.9 3.6e-14 53.4 0.2 2.4 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain Ank_2 PF12796.7 KER25134.1 - 1.3e-11 45.0 0.0 2.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER25134.1 - 2.5e-07 30.8 0.1 0.026 14.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER25134.1 - 1.7e-06 28.4 0.2 0.068 13.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KER25134.1 - 1.9e-06 28.0 0.4 0.044 14.2 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KER25134.1 - 2e-06 27.7 0.1 0.17 12.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat DUF2520 PF10728.9 KER25134.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) NSP2-B_epitope PF14757.6 KER25134.1 - 0.15 11.8 3.6 0.49 10.1 0.5 2.4 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein LSM PF01423.22 KER25135.1 - 2.9e-16 58.9 0.1 3.7e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain STAR_dimer PF16544.5 KER25136.1 - 3e-05 23.5 0.3 0.00028 20.4 0.3 2.2 1 1 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 KER25136.1 - 0.0031 17.3 0.1 0.0079 16.0 0.1 1.6 1 0 0 1 1 1 1 KH domain YAF2_RYBP PF17219.3 KER25137.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif ubiquitin PF00240.23 KER25138.1 - 1.3e-69 229.9 4.9 4.1e-34 116.2 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KER25138.1 - 1.9e-33 114.1 5.7 4.1e-16 58.6 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KER25138.1 - 6.2e-13 49.0 1.2 8.8e-05 22.9 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KER25138.1 - 2.2e-08 34.3 0.8 0.007 16.7 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 KER25138.1 - 4.7e-08 32.9 0.4 0.01 15.7 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KER25138.1 - 1.6e-07 31.4 0.5 0.029 14.4 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KER25138.1 - 2.4e-06 28.0 0.1 0.099 13.2 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KER25138.1 - 4.5e-05 23.4 8.8 5.7 7.1 0.2 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Big_7 PF17957.1 KER25138.1 - 0.00015 22.4 0.0 0.95 10.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial Ig domain Sde2_N_Ubi PF13019.6 KER25138.1 - 0.00016 21.6 0.0 0.49 10.2 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain HATPase_c PF02518.26 KER25138.1 - 0.00033 21.1 1.2 0.87 10.1 0.1 2.1 1 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3861 PF12977.7 KER25138.1 - 0.0064 16.6 0.3 3.7 7.8 0.0 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) PDGLE PF13190.6 KER25138.1 - 0.0094 15.8 1.1 4.6 7.2 0.1 2.7 1 1 1 2 2 2 2 PDGLE domain DUF2870 PF11069.8 KER25138.1 - 0.011 16.1 0.1 11 6.5 0.0 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2870) Big_3_3 PF13750.6 KER25138.1 - 0.031 13.9 0.0 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Methyltrans_RNA PF04452.14 KER25138.1 - 0.088 12.1 0.2 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA methyltransferase ACT_5 PF13710.6 KER25138.1 - 0.095 12.6 0.3 17 5.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain PurS PF02700.14 KER25138.1 - 0.099 12.8 0.6 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase UDP-g_GGTase PF06427.11 KER25138.1 - 0.1 12.8 0.8 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase FERM_f0 PF16511.5 KER25138.1 - 0.14 12.5 1.8 31 5.0 0.1 3.3 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 KER25138.1 - 0.7 8.5 4.0 9.6 4.7 0.3 2.8 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain ubiquitin PF00240.23 KER25139.1 - 1.6e-203 658.9 30.4 3.4e-33 113.2 0.4 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 KER25139.1 - 4e-95 311.7 33.0 3.3e-15 55.7 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KER25139.1 - 1.9e-34 118.0 15.1 0.00062 20.2 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KER25139.1 - 5.9e-22 77.9 14.0 0.048 14.0 0.1 6.1 1 1 5 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 KER25139.1 - 6.1e-22 77.4 10.2 0.067 13.1 0.0 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KER25139.1 - 2.2e-20 72.8 7.4 0.2 11.7 0.0 7.1 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KER25139.1 - 7e-19 68.3 3.5 0.68 10.5 0.0 6.2 1 1 2 6 6 6 6 DUF2407 ubiquitin-like domain Big_7 PF17957.1 KER25139.1 - 5e-15 56.0 0.3 5.3 7.9 0.0 6.2 6 0 0 6 6 6 6 Bacterial Ig domain DUF2870 PF11069.8 KER25139.1 - 7.2e-09 35.9 0.0 49 4.4 0.0 6.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 KER25139.1 - 1e-07 32.1 10.3 7.7 6.7 0.0 5.9 6 0 0 6 6 6 5 UDP-glucose:Glycoprotein Glucosyltransferase Ubiquitin_4 PF18036.1 KER25139.1 - 1.4e-07 31.4 42.2 28 4.8 0.2 11.9 12 0 0 12 12 12 0 Ubiquitin-like domain Big_3_3 PF13750.6 KER25139.1 - 1.6e-07 31.1 0.0 42 3.7 0.0 5.9 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.7 KER25139.1 - 3.6e-07 30.3 8.5 28 5.0 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 KER25139.1 - 2.2e-06 27.3 0.3 38 3.6 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 KER25139.1 - 4.6e-05 23.5 0.0 1.5e+02 2.6 0.0 6.5 6 0 0 6 6 6 0 ORF11CD3 domain PDGLE PF13190.6 KER25139.1 - 7.2e-05 22.6 14.1 30 4.6 0.1 6.8 1 1 2 6 6 6 0 PDGLE domain ACT_5 PF13710.6 KER25139.1 - 0.00045 20.0 8.8 74 3.3 0.0 6.2 6 0 0 6 6 6 0 ACT domain ACT_4 PF13291.6 KER25139.1 - 0.00052 20.5 3.3 2.4e+02 2.4 0.0 6.0 6 0 0 6 6 6 0 ACT domain Baculo_p48 PF04878.13 KER25139.1 - 0.028 13.4 0.0 1.6e+02 1.0 0.0 4.4 5 0 0 5 5 5 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 KER25139.1 - 0.035 14.2 12.5 1.3e+02 2.8 0.1 6.0 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KER25139.1 - 2.5 8.0 16.9 1.4e+02 2.4 0.1 6.1 6 0 0 6 6 6 0 FlgD Ig-like domain Ribosomal_L37e PF01907.19 KER25141.1 - 7.2e-10 38.9 1.4 1.6e-09 37.8 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e FYVE PF01363.21 KER25142.1 - 3.5e-14 52.7 16.8 1.3e-13 50.9 16.8 2.0 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 KER25142.1 - 0.54 10.3 11.7 0.18 11.9 7.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 KER25142.1 - 0.84 10.0 16.3 1.4 9.3 14.4 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 KER25142.1 - 3.2 7.8 20.9 2.4 8.2 16.1 3.0 2 0 0 2 2 2 0 zinc-RING finger domain UPF0506 PF11703.8 KER25145.1 - 2e-18 66.5 21.6 2.3e-18 66.3 21.6 1.0 1 0 0 1 1 1 1 UPF0506 Toxin_7 PF05980.12 KER25145.1 - 0.03 14.5 7.7 0.03 14.5 7.7 2.5 2 1 0 2 2 2 0 Toxin 7 Omega-toxin PF06357.11 KER25145.1 - 0.031 14.0 5.1 0.031 14.0 5.1 2.2 2 1 0 2 2 2 0 Omega-atracotoxin Conotoxin_I2 PF17557.2 KER25145.1 - 0.044 13.9 9.4 0.044 13.9 9.4 2.4 2 0 0 2 2 2 0 I2-superfamily conotoxins Dickkopf_N PF04706.12 KER25145.1 - 0.065 13.7 21.9 1.9 9.0 21.8 2.2 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_12 PF07740.12 KER25145.1 - 4.6 8.0 27.3 19 6.1 7.9 3.4 2 2 0 2 2 2 0 Ion channel inhibitory toxin UPF0506 PF11703.8 KER25146.1 - 6.1e-17 61.8 21.9 7.1e-17 61.5 21.9 1.1 1 0 0 1 1 1 1 UPF0506 Conotoxin_I2 PF17557.2 KER25146.1 - 0.072 13.2 9.1 0.072 13.2 9.1 2.4 2 1 0 2 2 2 0 I2-superfamily conotoxins RAMP4 PF06624.12 KER25146.1 - 0.73 9.9 2.1 1.1 9.4 2.1 1.2 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Conotoxin PF02950.17 KER25147.1 - 0.011 16.8 0.3 0.023 15.7 0.3 1.5 1 0 0 1 1 1 0 Conotoxin RRM_1 PF00076.22 KER25149.1 - 1e-14 54.1 0.0 1.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Diphthamide_syn PF01866.17 KER25151.1 - 9.5e-31 107.3 0.0 1.3e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Lig_chan PF00060.26 KER25151.1 - 0.083 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel ABC_membrane PF00664.23 KER25152.1 - 0.0092 15.7 2.7 0.011 15.4 2.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_A17 PF05380.13 KER25153.1 - 7e-21 74.9 0.0 7.9e-20 71.5 0.0 2.2 1 1 0 1 1 1 1 Pao retrotransposon peptidase zf-nanos PF05741.13 KER25153.1 - 0.002 18.3 0.7 4.5 7.6 0.0 3.3 3 0 0 3 3 3 2 Nanos RNA binding domain DUF3389 PF11869.8 KER25153.1 - 0.049 13.8 0.0 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) Ribosomal_L34 PF00468.17 KER25154.1 - 0.0051 16.7 0.3 0.0051 16.7 0.3 2.3 2 1 0 2 2 2 1 Ribosomal protein L34 Dynamitin PF04912.14 KER25155.1 - 8e-94 315.1 23.5 9e-94 315.0 23.5 1.0 1 0 0 1 1 1 1 Dynamitin DUF2408 PF10303.9 KER25155.1 - 0.01 16.4 11.7 0.21 12.2 6.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Laminin_II PF06009.12 KER25155.1 - 0.019 15.0 18.1 0.032 14.3 2.1 4.5 3 1 1 5 5 5 0 Laminin Domain II DUF3470 PF11953.8 KER25155.1 - 0.026 14.5 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) DUF713 PF05218.14 KER25155.1 - 0.073 12.8 8.2 0.051 13.3 3.7 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF713) FlaC_arch PF05377.11 KER25155.1 - 0.27 11.6 13.8 1.1 9.6 0.2 5.2 5 1 1 6 6 5 0 Flagella accessory protein C (FlaC) LemA PF04011.12 KER25155.1 - 0.35 10.7 3.5 5.6 6.8 3.3 2.6 1 1 0 1 1 1 0 LemA family SesA PF17107.5 KER25155.1 - 0.35 11.1 8.4 0.11 12.7 2.4 3.1 2 2 2 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TipAS PF07739.13 KER25155.1 - 0.44 11.1 2.4 1.6 9.3 0.1 2.8 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain V_ATPase_I PF01496.19 KER25155.1 - 0.69 7.8 6.4 0.28 9.1 3.1 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KER25155.1 - 0.71 8.4 5.6 0.54 8.8 1.7 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spectrin PF00435.21 KER25155.1 - 0.8 10.2 13.5 2.3 8.7 3.8 4.2 2 1 2 4 4 4 0 Spectrin repeat Occludin_ELL PF07303.13 KER25155.1 - 0.85 10.4 10.5 8 7.3 0.9 4.2 3 1 1 4 4 4 0 Occludin homology domain NPV_P10 PF05531.12 KER25155.1 - 1.4 9.4 15.3 6.3 7.3 2.3 5.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KER25155.1 - 1.7 7.4 22.1 0.19 10.6 9.1 3.0 2 2 1 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KER25155.1 - 2.2 8.3 16.0 6.1 6.9 5.0 3.9 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 KER25155.1 - 5 7.1 8.0 3.8 7.4 0.2 3.9 4 0 0 4 4 4 0 Heat shock factor binding protein 1 DUF5344 PF17279.2 KER25155.1 - 8.4 7.1 12.6 12 6.5 1.9 3.9 2 1 1 3 3 3 0 Family of unknown function (DUF5344) DUF2203 PF09969.9 KER25155.1 - 8.4 7.1 12.3 8.1 7.2 0.2 3.8 3 1 2 5 5 4 0 Uncharacterized conserved protein (DUF2203) BCNT PF07572.12 KER25158.1 - 1.7e-22 79.3 1.0 5.6e-22 77.6 1.0 1.9 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4969 PF16339.5 KER25158.1 - 0.49 10.8 4.2 1 9.8 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4969) NDUF_B8 PF05821.11 KER25159.1 - 3.1e-23 82.6 3.8 3.4e-23 82.4 3.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DRIM PF07539.12 KER25160.1 - 1.4e-156 522.4 15.8 1.4e-156 522.4 15.8 4.6 4 1 0 4 4 4 2 Down-regulated in metastasis HEAT_EZ PF13513.6 KER25160.1 - 0.0073 16.8 0.4 0.12 13.0 0.4 3.3 1 0 0 1 1 1 1 HEAT-like repeat Chromo PF00385.24 KER25163.1 - 1.3e-13 50.6 2.0 2.2e-13 49.9 2.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 KER25163.1 - 2e-10 40.2 0.0 6e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 CBX family C-terminal motif DUF2594 PF10769.9 KER25166.1 - 0.074 13.1 0.0 4 7.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2594) Hormone_2 PF00123.20 KER25166.1 - 0.31 11.0 8.1 3.2 7.7 0.2 2.9 3 0 0 3 3 3 0 Peptide hormone SpoIIIAH PF12685.7 KER25169.1 - 0.042 13.7 2.4 0.05 13.4 2.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 KER25169.1 - 0.15 10.8 7.0 0.15 10.8 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KER25169.1 - 0.19 11.1 41.6 0.23 10.9 41.6 1.0 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KER25169.1 - 0.29 10.1 0.2 0.34 9.8 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KER25169.1 - 1.9 6.6 41.7 2.3 6.3 41.7 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KER25169.1 - 5.2 6.4 31.1 7.5 5.8 31.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BTB_3 PF16017.5 KER25171.1 - 3.5e-44 149.2 0.0 8.6e-44 148.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 KER25171.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain Kelch_4 PF13418.6 KER25172.1 - 0.00017 21.5 1.9 0.16 12.0 0.1 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KER25172.1 - 0.0013 19.0 0.7 4.1 7.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KER25172.1 - 0.0015 18.5 1.7 0.026 14.5 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 KER25172.1 - 0.003 17.1 1.0 1.8 8.2 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KER25172.1 - 0.15 12.4 7.5 4.4 7.7 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain ADP_ribosyl_GH PF03747.14 KER25174.1 - 3.4e-42 145.1 0.0 5e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Asp_protease_2 PF13650.6 KER25174.1 - 0.0019 18.8 0.1 0.0094 16.6 0.0 2.1 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KER25174.1 - 0.014 16.0 0.0 0.056 14.0 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-HYPF PF07503.12 KER25174.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 HypF finger Tsp45I PF06300.12 KER25174.1 - 0.24 10.9 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme CUB PF00431.20 KER25175.1 - 4.6e-19 68.8 0.0 1.5e-08 35.0 0.0 2.6 2 1 0 2 2 2 2 CUB domain VAD1-2 PF15310.6 KER25178.1 - 0.024 14.5 0.1 0.029 14.3 0.1 1.0 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling DUF1926 PF09095.11 KER25178.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) DUF1754 PF08555.10 KER25181.1 - 0.023 15.5 10.2 1.1 10.1 10.2 2.2 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CBP_BcsG PF11658.8 KER25181.1 - 0.046 12.1 0.7 0.05 12.0 0.7 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG UPF0172 PF03665.13 KER25181.1 - 0.049 13.7 0.2 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) MMR_HSR1 PF01926.23 KER25182.1 - 1.9e-15 56.9 0.3 2.6e-12 46.8 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase RVT_1 PF00078.27 KER25182.1 - 3.6e-14 52.8 0.0 7.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FeoB_N PF02421.18 KER25182.1 - 2e-11 43.6 0.1 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B MULE PF10551.9 KER25182.1 - 1.4e-07 31.8 0.1 5.6e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain Dynamin_N PF00350.23 KER25182.1 - 2.1e-05 24.7 0.1 0.66 10.0 0.1 3.3 2 1 1 3 3 3 3 Dynamin family RsgA_GTPase PF03193.16 KER25182.1 - 5e-05 23.3 0.2 0.42 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KER25182.1 - 0.00035 20.0 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KER25182.1 - 0.0057 16.2 0.0 0.1 12.1 0.0 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KER25182.1 - 0.16 11.4 0.1 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TGT PF01702.18 KER25183.1 - 5.8e-44 150.7 0.0 7.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase WCCH PF03716.14 KER25183.1 - 0.24 11.1 2.0 0.44 10.3 2.0 1.4 1 0 0 1 1 1 0 WCCH motif adh_short PF00106.25 KER25186.1 - 1.1e-30 106.5 1.2 8e-23 80.9 0.0 2.9 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KER25186.1 - 7.9e-21 74.7 0.0 3.8e-16 59.3 0.0 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER25186.1 - 0.00018 21.5 0.1 0.00048 20.1 0.1 1.7 1 1 0 1 1 1 1 KR domain Tubulin PF00091.25 KER25187.1 - 3.6e-125 415.7 0.0 2.7e-62 210.5 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25187.1 - 5e-84 278.8 0.0 5e-44 149.5 0.0 2.4 2 0 0 2 2 2 2 Tubulin C-terminal domain DUF282 PF03380.14 KER25187.1 - 0.012 15.6 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 vWF_A PF12450.8 KER25187.1 - 0.073 13.0 0.1 9.8 6.2 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor Tubulin_2 PF13809.6 KER25187.1 - 0.22 10.7 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 KER25188.1 - 3.8e-61 206.7 0.0 5.2e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25188.1 - 1.5e-49 167.3 0.0 2.7e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER25188.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 KER25190.1 - 1.6e-64 217.8 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25190.1 - 3.2e-46 156.6 0.0 5.2e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER25190.1 - 0.00034 20.4 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain zf-C2H2_jaz PF12171.8 KER25191.1 - 3.1e-10 40.1 0.9 3.1e-10 40.1 0.9 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER25191.1 - 0.0018 18.6 1.3 0.0026 18.1 0.3 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zinc_ribbon_11 PF11682.8 KER25191.1 - 0.02 14.9 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon PRKCSH-like PF12999.7 KER25193.1 - 6.8e-39 133.4 1.1 1.1e-38 132.8 1.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KER25193.1 - 2.1e-17 63.2 0.1 4e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KER25193.1 - 4.6e-09 37.2 0.3 4.6e-09 37.2 0.3 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 KER25193.1 - 0.0019 18.4 13.8 0.48 10.7 2.6 2.9 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A eIF_4EBP PF05456.11 KER25195.1 - 5.1e-37 126.3 0.5 5.8e-37 126.2 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Lactamase_B_6 PF16661.5 KER25195.1 - 0.27 10.7 0.0 0.34 10.3 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF716 PF04819.12 KER25196.1 - 2.8e-17 62.7 5.3 5e-17 61.8 5.1 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF716) BAF250_C PF12031.8 KER25197.1 - 4e-82 275.4 0.0 6.2e-82 274.7 0.0 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 KER25197.1 - 3.4e-12 46.8 0.0 7.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RVT_1 PF00078.27 KER25197.1 - 1e-07 31.7 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Aconitase PF00330.20 KER25198.1 - 8.8e-152 506.3 0.0 1.1e-151 506.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KER25198.1 - 3.4e-33 114.8 0.0 3.3e-31 108.3 0.0 2.5 1 1 0 1 1 1 1 Aconitase C-terminal domain PHD PF00628.29 KER25199.1 - 3.9e-06 26.6 10.5 8e-06 25.7 10.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KER25199.1 - 0.077 13.1 9.0 0.15 12.1 9.0 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KER25199.1 - 1.3 8.9 10.6 0.089 12.7 4.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPX PF03105.19 KER25199.1 - 5.2 6.9 8.1 7.7 6.3 8.1 1.3 1 0 0 1 1 1 0 SPX domain LSM14 PF12701.7 KER25202.1 - 1.8e-11 43.9 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KER25202.1 - 3.4e-05 23.9 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KER25202.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 LSM domain TCR PF03638.15 KER25203.1 - 2.8e-21 75.6 44.9 1.2e-11 44.7 22.2 2.5 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain betaPIX_CC PF16523.5 KER25203.1 - 0.59 10.0 5.4 2 8.3 1.5 2.3 2 0 0 2 2 2 0 betaPIX coiled coil DUF3592 PF12158.8 KER25207.1 - 0.034 14.2 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Tubulin PF00091.25 KER25208.1 - 2.1e-63 214.1 0.0 3.7e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25208.1 - 7.2e-44 149.0 0.3 1.2e-43 148.3 0.3 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER25208.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KER25208.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KER25208.1 - 0.15 11.2 0.1 0.32 10.1 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Sedlin_N PF04628.13 KER25209.1 - 2.7e-20 72.8 0.0 3.8e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3523 PF12037.8 KER25210.1 - 8.5e-94 313.8 26.9 1.6e-93 312.9 26.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 KER25210.1 - 1.3e-22 80.7 0.0 2.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KER25210.1 - 6.4e-05 23.1 3.3 6.5e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KER25210.1 - 0.00011 21.7 0.1 0.0012 18.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KER25210.1 - 0.00018 21.9 5.4 0.00049 20.5 0.0 3.2 2 2 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KER25210.1 - 0.00036 20.8 1.6 0.92 9.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KER25210.1 - 0.00045 20.4 0.0 0.00097 19.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 KER25210.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER25210.1 - 0.0047 16.9 1.6 0.009 16.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KER25210.1 - 0.011 15.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KER25210.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KER25210.1 - 0.022 15.3 0.0 0.022 15.3 0.0 2.5 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KER25210.1 - 0.028 14.2 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KER25210.1 - 0.035 14.0 0.4 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KER25210.1 - 0.037 14.0 1.9 0.083 12.9 0.0 2.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KER25210.1 - 0.042 14.2 0.0 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KER25210.1 - 0.043 13.4 0.1 0.19 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 KER25210.1 - 0.051 13.4 0.9 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 AAA+ lid domain AAA_7 PF12775.7 KER25210.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KER25210.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.1 2 1 1 3 3 2 0 AAA domain AAA_11 PF13086.6 KER25210.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.1 2 1 1 3 3 1 0 AAA domain Phospholip_B PF04916.13 KER25211.1 - 1.5e-138 462.7 2.5 1.9e-138 462.3 2.5 1.0 1 0 0 1 1 1 1 Phospholipase B Syd PF07348.12 KER25212.1 - 0.12 12.0 0.8 1.1 8.9 0.1 2.1 1 1 0 2 2 2 0 Syd protein (SUKH-2) Spore_Cse60 PF10957.8 KER25215.1 - 0.074 13.1 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein Cse60 fn3 PF00041.21 KER25217.1 - 1.3e-05 25.5 4.5 0.0051 17.1 0.2 3.4 3 0 0 3 3 3 1 Fibronectin type III domain Ank_5 PF13857.6 KER25217.1 - 0.018 15.4 0.2 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Defensin_big PF14862.6 KER25217.1 - 0.022 15.1 0.0 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Big defensin Pur_ac_phosph_N PF16656.5 KER25217.1 - 0.051 14.2 2.9 11 6.7 0.1 3.4 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain RVT_1 PF00078.27 KER25219.1 - 3.1e-14 53.0 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cullin PF00888.22 KER25220.1 - 3.2e-210 699.9 14.0 3.8e-209 696.3 14.0 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KER25220.1 - 1.9e-26 91.8 0.4 7e-26 90.1 0.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HrcA PF01628.21 KER25220.1 - 0.043 13.7 0.6 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 HrcA protein C terminal domain DUF4101 PF13355.6 KER25220.1 - 0.13 12.7 0.4 0.54 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) DUF953 PF06110.11 KER25221.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Nfu_N PF08712.11 KER25222.1 - 1.7e-32 111.3 0.0 3.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KER25222.1 - 6.3e-27 93.5 0.1 9.6e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Stevor PF17410.2 KER25223.1 - 0.0019 17.8 1.2 0.0019 17.8 1.2 1.8 1 1 1 2 2 2 1 Subtelomeric Variable Open Reading frame HlyIII PF03006.20 KER25223.1 - 0.0054 16.5 4.7 0.0054 16.5 4.7 1.5 2 0 0 2 2 2 1 Haemolysin-III related Ac76 PF05814.11 KER25223.1 - 0.015 15.3 4.1 0.015 15.3 4.1 2.7 3 0 0 3 3 3 0 Orf76 (Ac76) EpsG PF14897.6 KER25223.1 - 0.057 12.7 7.9 0.083 12.2 7.9 1.3 1 1 0 1 1 1 0 EpsG family PalH PF08733.10 KER25223.1 - 0.084 11.9 6.2 0.13 11.2 6.2 1.3 1 0 0 1 1 1 0 PalH/RIM21 Pox_P35 PF03213.14 KER25223.1 - 0.3 10.3 3.3 0.48 9.6 3.3 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein DUF1345 PF07077.11 KER25223.1 - 0.39 10.4 7.2 0.09 12.5 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4293 PF14126.6 KER25223.1 - 0.62 10.3 11.7 0.92 9.8 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4173 PF13777.6 KER25223.1 - 0.63 9.4 13.2 0.018 14.5 6.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF4064 PF13273.6 KER25223.1 - 0.66 10.3 13.1 0.038 14.3 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Virul_fac_BrkB PF03631.15 KER25223.1 - 1 8.9 11.1 1.4 8.4 11.1 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF202 PF02656.15 KER25223.1 - 1.7 9.2 7.6 0.95 9.9 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Saf_2TM PF18303.1 KER25223.1 - 2.4 7.7 8.2 8.2 6.0 0.0 2.8 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain DHHC PF01529.20 KER25223.1 - 3.7 7.7 13.8 1.9 8.6 2.3 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Yip1 PF04893.17 KER25223.1 - 3.7 7.2 14.9 16 5.2 14.9 1.8 1 1 0 1 1 1 0 Yip1 domain DUF2842 PF11003.8 KER25223.1 - 3.8 7.8 15.2 0.11 12.7 4.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) Ost5 PF05251.12 KER25223.1 - 5.4 7.3 17.1 0.32 11.3 5.7 3.1 1 1 1 3 3 3 0 Oligosaccharyltransferase subunit 5 DUF2070 PF09843.9 KER25223.1 - 7.7 4.7 13.7 9.4 4.4 13.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 KER25223.1 - 8.9 5.9 9.2 55 3.4 8.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DSPc PF00782.20 KER25225.1 - 1.7e-12 47.3 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 KER25225.1 - 2.4e-12 47.5 0.0 1.7e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 KER25225.1 - 0.00013 22.2 0.1 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KER25225.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Kinesin PF00225.23 KER25228.1 - 3.2e-61 207.1 0.2 6.9e-38 130.4 0.0 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KER25228.1 - 8.4e-19 68.0 0.0 1.8e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 KER25228.1 - 4.8e-08 33.4 7.1 1.7e-06 28.3 3.0 2.5 1 1 1 2 2 2 2 Kinesin-associated KIF1B PF12423.8 KER25228.1 - 0.00052 20.4 0.8 0.00052 20.4 0.8 2.2 2 0 0 2 2 2 1 Kinesin protein 1B AAA_32 PF13654.6 KER25228.1 - 0.002 17.0 5.4 0.0039 16.1 5.4 1.4 1 0 0 1 1 1 1 AAA domain FHA PF00498.26 KER25228.1 - 0.026 14.9 0.0 0.51 10.7 0.0 2.9 3 0 0 3 3 3 0 FHA domain Resolvase PF00239.21 KER25228.1 - 0.077 13.1 1.3 0.9 9.6 0.0 2.6 1 1 1 2 2 2 0 Resolvase, N terminal domain DUF2181 PF10223.9 KER25228.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) SWIB PF02201.18 KER25229.1 - 1.1e-21 76.4 0.0 4.1e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain PTPLA PF04387.14 KER25230.1 - 1.9e-18 66.7 6.6 3.6e-12 46.3 3.8 2.1 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA YGGT PF02325.17 KER25230.1 - 0.2 12.1 6.3 0.063 13.7 3.6 1.6 2 0 0 2 2 2 0 YGGT family NTP_transf_9 PF04248.12 KER25231.1 - 0.044 13.7 0.2 0.056 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Glycos_transf_2 PF00535.26 KER25232.1 - 3.4e-34 118.1 0.0 5.4e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KER25232.1 - 6.2e-17 62.0 0.1 9.4e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 KER25232.1 - 1.8e-08 34.6 0.0 1e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 KER25232.1 - 3e-06 26.8 0.3 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 KER25232.1 - 0.0037 16.8 0.0 0.02 14.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 WD40_like PF17005.5 KER25235.1 - 0.0051 16.2 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain RabGAP-TBC PF00566.18 KER25235.1 - 0.23 11.1 3.2 0.39 10.3 3.2 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain WD40 PF00400.32 KER25235.1 - 2 9.4 9.1 15 6.7 2.7 4.7 5 1 0 5 5 5 0 WD domain, G-beta repeat zf-C2H2_12 PF18658.1 KER25236.1 - 0.15 11.6 0.5 0.88 9.2 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-BED PF02892.15 KER25236.1 - 0.2 11.7 0.2 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 BED zinc finger Ndc1_Nup PF09531.10 KER25237.1 - 2.7e-13 49.5 0.0 6.7e-12 44.9 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Bac_chlorC PF02043.17 KER25237.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Arf PF00025.21 KER25238.1 - 2.4e-45 154.1 0.0 3.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KER25238.1 - 1.3e-11 44.7 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER25238.1 - 3.2e-11 43.1 0.0 3.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KER25238.1 - 1.3e-10 41.0 0.1 4.4e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KER25238.1 - 1e-07 31.6 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KER25238.1 - 5.1e-06 26.0 0.0 7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KER25238.1 - 2.1e-05 24.6 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Tubulin PF00091.25 KER25239.1 - 1.7e-14 54.5 0.0 2.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.32 KER25240.1 - 2.5e-07 31.3 7.4 0.009 16.9 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Complex1_30kDa PF00329.19 KER25241.1 - 3.8e-40 137.3 0.0 5.3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF3731 PF12531.8 KER25242.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 DNA-K related protein Hid1 PF12722.7 KER25243.1 - 5.3 5.0 11.3 6 4.9 11.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tubulin PF00091.25 KER25244.1 - 4.4e-125 415.4 0.0 9.9e-69 231.5 0.0 3.3 3 0 0 3 3 3 3 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25244.1 - 1.3e-88 293.5 1.2 5.2e-43 146.2 0.1 2.3 2 0 0 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER25244.1 - 1.5e-06 28.0 0.0 0.039 13.6 0.0 2.5 2 0 0 2 2 2 2 Tubulin domain Tubulin_2 PF13809.6 KER25244.1 - 4.1e-06 26.2 0.0 0.085 12.0 0.0 2.5 2 0 0 2 2 2 2 Tubulin like Misat_Tub_SegII PF10644.9 KER25244.1 - 6.1e-06 26.5 0.0 8.1e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain TrmK PF04816.12 KER25244.1 - 0.0033 17.0 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 tRNA (adenine(22)-N(1))-methyltransferase Het-C PF07217.11 KER25244.1 - 0.023 13.3 0.0 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF5008 PF16400.5 KER25244.1 - 0.07 13.2 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5008) S_locus_glycop PF00954.20 KER25244.1 - 0.39 11.3 2.9 26 5.4 0.1 3.4 4 0 0 4 4 4 0 S-locus glycoprotein domain cEGF PF12662.7 KER25244.1 - 0.73 9.8 6.1 7.7 6.6 0.8 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like Bombesin PF02044.17 KER25244.1 - 1.5 9.1 7.9 16 5.8 1.0 3.0 2 0 0 2 2 2 0 Bombesin-like peptide Tubulin PF00091.25 KER25245.1 - 1.1e-69 234.6 0.0 1.9e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25245.1 - 1.2e-44 151.5 0.1 2.1e-44 150.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER25245.1 - 4.2e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KER25245.1 - 0.0049 16.6 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 KER25245.1 - 0.034 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like RPEL PF02755.15 KER25247.1 - 3.2e-22 77.5 6.4 6e-09 35.3 0.2 3.6 3 0 0 3 3 3 3 RPEL repeat MT PF12777.7 KER25251.1 - 8.7e-167 554.4 12.0 8.7e-167 554.4 12.0 2.8 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 KER25251.1 - 6.7e-154 511.7 0.0 1.5e-150 500.7 0.0 3.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER25251.1 - 1.9e-115 386.2 19.4 1.9e-115 386.2 19.4 4.9 6 1 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KER25251.1 - 9.6e-107 357.9 41.6 5.3e-72 243.2 0.8 6.9 5 2 0 6 6 5 3 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 KER25251.1 - 2.9e-98 328.3 0.0 8.4e-98 326.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER25251.1 - 3.3e-97 325.4 0.4 1.4e-96 323.4 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER25251.1 - 1.8e-85 285.6 0.3 1.8e-85 285.6 0.3 2.7 3 0 0 3 3 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER25251.1 - 5.5e-76 254.1 0.0 5.1e-69 231.4 0.0 4.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER25251.1 - 3.7e-55 186.2 0.0 1.1e-54 184.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER25251.1 - 2.2e-40 137.5 0.0 4.9e-38 129.9 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KER25251.1 - 1.1e-37 128.3 0.5 1.1e-37 128.3 0.5 3.3 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KER25251.1 - 2.3e-27 95.6 0.1 1.5e-26 92.9 0.1 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER25251.1 - 8.8e-24 84.1 0.0 1.3e-10 41.4 0.0 5.5 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER25251.1 - 6.3e-07 29.7 2.8 0.58 10.4 0.0 5.4 6 0 0 6 6 3 2 AAA domain AAA_16 PF13191.6 KER25251.1 - 1.5e-06 28.7 1.7 0.16 12.4 0.0 5.4 4 1 1 5 5 4 2 AAA ATPase domain AAA PF00004.29 KER25251.1 - 2.3e-05 24.8 0.2 0.96 9.9 0.0 5.4 6 0 0 6 6 4 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KER25251.1 - 4.2e-05 23.3 0.0 0.085 12.6 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_30 PF13604.6 KER25251.1 - 0.0001 22.1 0.8 1.9 8.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KER25251.1 - 0.00032 20.6 0.0 0.12 12.3 0.0 3.9 2 0 0 2 2 2 1 NACHT domain PRO8NT PF08082.11 KER25251.1 - 0.0015 18.5 1.5 2.7 7.9 0.0 3.3 3 0 0 3 3 2 2 PRO8NT (NUC069), PrP8 N-terminal domain AAA_18 PF13238.6 KER25251.1 - 0.0019 18.7 1.1 2.5 8.6 0.0 5.4 6 0 0 6 6 3 1 AAA domain T2SSE PF00437.20 KER25251.1 - 0.0024 17.0 0.1 0.39 9.7 0.0 3.8 4 0 0 4 4 3 1 Type II/IV secretion system protein TsaE PF02367.17 KER25251.1 - 0.004 17.2 0.3 0.62 10.1 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 KER25251.1 - 0.0047 16.1 0.2 0.11 11.6 0.0 3.1 3 0 0 3 3 3 1 PIF1-like helicase AAA_24 PF13479.6 KER25251.1 - 0.0079 15.9 0.1 4.3 7.0 0.0 4.0 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 KER25251.1 - 0.013 15.7 0.0 9.3 6.4 0.0 3.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KER25251.1 - 0.035 13.5 0.7 1.8 7.9 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KER25251.1 - 0.035 13.5 0.2 15 5.0 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein BORCS6 PF10157.9 KER25251.1 - 0.041 14.1 0.1 0.041 14.1 0.1 2.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 CheY-binding PF09078.11 KER25251.1 - 0.046 13.8 2.1 11 6.2 0.2 2.9 2 0 0 2 2 2 0 CheY binding AAA_19 PF13245.6 KER25251.1 - 0.048 14.0 7.0 16 5.8 0.0 5.3 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.22 KER25251.1 - 0.066 13.6 0.0 99 3.4 0.0 3.9 3 0 0 3 3 3 0 RNA helicase Roc PF08477.13 KER25251.1 - 0.1 12.8 1.4 17 5.7 0.0 3.6 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Rop-like PF05082.13 KER25251.1 - 0.16 11.8 9.7 2.3 8.1 0.3 3.7 3 0 0 3 3 2 0 Rop-like PilJ PF13675.6 KER25251.1 - 0.3 11.1 30.5 0.092 12.8 0.4 6.6 7 0 0 7 7 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.12 KER25251.1 - 0.33 11.4 9.3 15 6.2 0.2 4.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATP_bind_1 PF03029.17 KER25251.1 - 1.6 8.5 9.3 0.81 9.4 0.0 5.0 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein CRISPR_Cas9_WED PF18061.1 KER25251.1 - 4.7 7.3 5.8 11 6.1 0.6 3.4 3 0 0 3 3 3 0 CRISPR-Cas9 WED domain DUF4140 PF13600.6 KER25251.1 - 8 7.0 8.6 4.8 7.7 0.3 4.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) LRR_8 PF13855.6 KER25253.1 - 4e-05 23.3 2.5 8.5e-05 22.2 2.5 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KER25253.1 - 0.0049 17.2 1.5 0.013 15.9 1.5 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) STAG PF08514.11 KER25254.1 - 0.099 12.6 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 STAG domain Thioredoxin_7 PF13899.6 KER25255.1 - 4e-14 52.6 0.0 7.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KER25255.1 - 9.3e-09 35.4 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 KER25255.1 - 0.0021 18.1 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 KER25255.1 - 0.0024 18.3 0.0 0.0043 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UIM PF02809.20 KER25255.1 - 0.028 14.3 1.8 0.075 13.0 1.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif PHD PF00628.29 KER25256.1 - 8e-13 48.1 19.8 3.3e-07 30.1 5.6 2.9 2 1 1 3 3 3 2 PHD-finger Requiem_N PF14051.6 KER25256.1 - 1.5e-06 28.3 0.1 4.3e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. AEP1 PF17049.5 KER25257.1 - 0.032 13.3 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 NIF PF03031.18 KER25258.1 - 3.3e-17 62.7 0.0 6.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4777 PF16007.5 KER25261.1 - 0.069 13.4 0.0 19 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) MRP-63 PF14978.6 KER25263.1 - 3.1e-10 40.5 0.4 3.7e-10 40.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 RyR PF02026.16 KER25263.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 RyR domain Reticulon PF02453.17 KER25265.1 - 5.7e-27 94.6 4.5 6.8e-27 94.4 4.5 1.1 1 0 0 1 1 1 1 Reticulon PRT_C PF08372.10 KER25265.1 - 0.00016 21.5 0.6 0.11 12.3 0.5 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal FERM_C PF09380.10 KER25266.1 - 1.9e-10 41.0 0.1 5.5e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KER25266.1 - 0.00038 20.3 0.2 0.00095 19.1 0.2 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KER25266.1 - 0.048 14.1 0.0 0.93 9.9 0.0 2.7 1 1 1 2 2 2 0 FERM central domain 2C_adapt PF08793.10 KER25267.1 - 0.0095 16.1 0.5 0.05 13.8 0.0 2.3 3 0 0 3 3 3 1 2-cysteine adaptor domain DUF4817 PF16087.5 KER25268.1 - 3.3e-14 52.4 0.0 6.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) GPI2 PF06432.11 KER25269.1 - 6.6e-29 101.2 13.0 7.3e-29 101.1 13.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3810 PF12725.7 KER25269.1 - 3.9 6.7 5.2 1.1 8.6 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Img2 PF05046.14 KER25271.1 - 8.5e-23 80.5 0.0 1.3e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF4739 PF15893.5 KER25271.1 - 0.066 12.8 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) Asp PF00026.23 KER25274.1 - 0.036 13.5 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Tctex-1 PF03645.13 KER25275.1 - 9.1e-24 83.7 0.5 1.6e-23 82.9 0.5 1.3 1 0 0 1 1 1 1 Tctex-1 family MHC_I PF00129.18 KER25275.1 - 0.021 14.4 0.0 0.047 13.2 0.0 1.5 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF5012 PF16404.5 KER25275.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Ank_4 PF13637.6 KER25276.1 - 2.2e-14 53.6 1.9 1.3e-08 35.2 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER25276.1 - 1.4e-13 50.8 0.5 5.4e-09 36.1 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER25276.1 - 2.7e-13 50.3 0.2 5.6e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER25276.1 - 7.6e-13 48.3 0.3 4.8e-08 33.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KER25276.1 - 1.5e-11 43.4 0.3 2.8e-05 24.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat PDZ PF00595.24 KER25277.1 - 1.1e-48 163.4 0.0 4.2e-14 52.6 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 KER25277.1 - 8.1e-33 112.1 3.4 6.3e-08 32.4 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 KER25277.1 - 8e-17 61.3 0.0 0.00054 20.2 0.1 4.4 4 0 0 4 4 4 4 PDZ domain ScdA_N PF04405.14 KER25278.1 - 0.14 11.8 1.0 0.27 10.9 1.0 1.4 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) PDZ PF00595.24 KER25280.1 - 5.8e-21 74.6 0.0 3.8e-05 23.9 0.1 5.1 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 KER25280.1 - 3e-14 52.6 0.2 0.0064 16.3 0.0 4.8 5 0 0 5 5 5 3 PDZ domain PDZ_2 PF13180.6 KER25280.1 - 7.1e-09 35.9 0.0 0.07 13.5 0.0 3.9 4 0 0 4 4 4 3 PDZ domain DNA_pol_phi PF04931.13 KER25282.1 - 0.015 13.5 23.6 0.022 12.9 23.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 KER25282.1 - 0.16 11.3 7.9 0.24 10.8 7.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 KER25282.1 - 0.58 9.0 5.8 0.68 8.8 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 KER25282.1 - 0.85 7.8 15.1 1.1 7.3 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KER25282.1 - 0.99 8.5 34.0 2.6 7.1 33.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KER25282.1 - 6 5.0 14.7 8.6 4.5 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 KER25282.1 - 6.9 6.5 7.5 10 5.9 7.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFIID_20kDa PF03847.13 KER25283.1 - 0.11 13.0 0.2 0.24 11.9 0.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A RasGEF PF00617.19 KER25285.1 - 6e-32 111.3 1.7 1.1e-31 110.4 1.7 1.5 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 KER25285.1 - 1.2e-11 44.5 0.0 4.8e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 KER25285.1 - 0.00025 21.2 1.2 0.0017 18.6 0.3 2.7 2 1 0 2 2 2 1 RasGEF N-terminal motif PCI PF01399.27 KER25287.1 - 4.3e-17 62.6 0.0 2e-16 60.4 0.0 2.1 2 1 0 2 2 2 1 PCI domain eIF3_N PF09440.10 KER25287.1 - 3.3e-14 53.5 1.6 1.2e-13 51.7 1.6 1.9 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain RPN7 PF10602.9 KER25287.1 - 2.8e-05 23.9 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Ribosomal_S25 PF03297.15 KER25287.1 - 0.0025 18.0 0.1 18 5.6 0.0 3.5 2 1 1 3 3 3 2 S25 ribosomal protein DUF771 PF05595.11 KER25287.1 - 0.025 14.5 0.1 0.54 10.2 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF771) MJ1316 PF04457.12 KER25287.1 - 0.033 14.9 0.0 12 6.8 0.0 2.7 2 0 0 2 2 2 0 MJ1316 RNA cyclic group end recognition domain Death_2 PF14786.6 KER25288.1 - 0.14 12.1 0.0 9.6 6.1 0.0 2.6 1 1 0 1 1 1 0 Tube Death domain Zn_Tnp_IS1 PF03811.13 KER25289.1 - 0.57 9.9 7.0 19 5.1 0.0 4.6 5 0 0 5 5 5 0 InsA N-terminal domain RRM_1 PF00076.22 KER25291.1 - 3.4e-19 68.4 0.0 4.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER25292.1 - 2.3e-20 72.2 0.2 7.9e-15 54.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 KER25293.1 - 0.002 17.6 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IDO PF01231.18 KER25294.1 - 5.8e-66 223.1 0.0 7.3e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.18 KER25297.1 - 1.6e-29 103.0 0.5 2.8e-29 102.2 0.5 1.4 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RVT_1 PF00078.27 KER25298.1 - 4.3e-28 98.3 0.0 8e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyridoxal_deC PF00282.19 KER25298.1 - 1e-24 87.0 0.0 1.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Exo_endo_phos_2 PF14529.6 KER25298.1 - 4.6e-07 29.7 0.0 9.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Aminotran_5 PF00266.19 KER25298.1 - 0.00062 18.8 0.0 0.0022 17.0 0.0 1.8 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KER25298.1 - 0.034 13.4 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Consortin_C PF15281.6 KER25300.1 - 0.72 9.9 0.1 0.72 9.9 0.1 2.1 2 0 0 2 2 2 0 Consortin C-terminus Wzy_C PF04932.15 KER25300.1 - 1.1 8.9 5.7 1.4 8.6 5.7 1.2 1 0 0 1 1 1 0 O-Antigen ligase Noc2 PF03715.13 KER25301.1 - 0.008 15.5 0.5 0.027 13.7 0.5 1.8 1 0 0 1 1 1 1 Noc2p family Cob_adeno_trans PF01923.18 KER25301.1 - 0.076 13.2 0.1 0.076 13.2 0.1 4.1 3 2 0 3 3 3 0 Cobalamin adenosyltransferase MAD PF05557.13 KER25301.1 - 0.12 10.7 44.3 0.14 10.5 6.5 3.7 3 1 0 3 3 3 0 Mitotic checkpoint protein ATG16 PF08614.11 KER25301.1 - 0.23 11.6 48.1 0.94 9.7 22.8 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 KER25301.1 - 0.26 10.9 44.1 0.092 12.3 2.6 4.7 4 1 1 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lebercilin PF15619.6 KER25301.1 - 5.1 6.7 51.1 0.65 9.6 20.8 4.9 4 1 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 KER25301.1 - 5.5 7.2 47.1 0.29 11.3 6.3 5.2 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Kelch_4 PF13418.6 KER25302.1 - 4.5e-17 61.8 4.1 0.023 14.7 0.0 6.2 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KER25302.1 - 5e-11 42.3 0.8 0.00023 21.1 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KER25302.1 - 3.2e-09 36.9 9.6 0.22 11.9 0.2 7.2 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KER25302.1 - 3.6e-09 36.6 3.5 0.00097 19.3 0.1 5.4 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 KER25302.1 - 1.5e-05 24.5 4.2 0.016 14.8 0.1 4.8 4 1 1 5 5 5 1 Kelch motif Fe_hyd_lg_C PF02906.14 KER25302.1 - 0.034 13.8 1.3 0.049 13.3 1.3 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain LRR_4 PF12799.7 KER25303.1 - 2.1e-07 31.1 4.2 6.1e-06 26.5 1.5 2.5 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER25303.1 - 0.00011 21.9 3.3 0.0013 18.5 2.7 2.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 KER25303.1 - 0.0022 17.5 0.3 0.0036 16.8 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Phage_GPO PF05929.11 KER25303.1 - 0.014 15.0 2.0 0.019 14.6 2.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LRR_1 PF00560.33 KER25303.1 - 0.031 14.8 3.8 5.3 8.0 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat SF-assemblin PF06705.11 KER25303.1 - 0.036 13.4 0.8 0.046 13.1 0.8 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Acyl_transf_1 PF00698.21 KER25303.1 - 0.063 12.8 0.3 0.13 11.7 0.2 1.5 1 1 0 1 1 1 0 Acyl transferase domain CHIP_TPR_N PF18391.1 KER25303.1 - 0.23 12.2 2.2 0.9 10.3 2.2 2.1 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain LRR_6 PF13516.6 KER25303.1 - 0.35 11.1 1.9 26 5.2 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich repeat DDE_1 PF03184.19 KER25304.1 - 7e-35 120.2 0.0 1.6e-34 119.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KER25304.1 - 7e-16 58.0 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KER25304.1 - 1.7e-08 34.0 0.6 3.2e-08 33.1 0.6 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KER25304.1 - 0.00029 20.5 0.6 0.00078 19.2 0.4 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KER25304.1 - 0.0086 15.8 0.5 0.028 14.2 0.5 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 KER25304.1 - 0.0099 15.9 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KER25304.1 - 0.041 14.0 0.2 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PP2C PF00481.21 KER25308.1 - 4.2e-23 82.3 0.0 1.1e-11 44.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KER25308.1 - 1.7e-05 24.5 0.0 5.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C CX9C PF16860.5 KER25309.1 - 0.0023 17.9 10.9 0.031 14.3 0.5 2.6 3 0 0 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KER25309.1 - 0.035 14.3 0.3 0.035 14.3 0.3 2.6 2 1 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 KER25309.1 - 0.89 9.6 9.3 0.25 11.4 0.7 2.6 1 1 3 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KER25309.1 - 3.2 8.1 8.6 0.19 12.0 1.7 2.4 2 1 1 3 3 3 0 Cytochrome oxidase c subunit VIb Tyrosinase PF00264.20 KER25310.1 - 5.5e-29 102.0 0.6 9.2e-29 101.3 0.6 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.24 KER25310.1 - 0.16 12.1 16.0 9.5 6.5 13.0 3.5 2 1 0 2 2 2 0 Laminin EGF domain Tyrosinase PF00264.20 KER25311.1 - 3.7e-58 197.4 0.2 2.7e-30 106.3 0.0 2.6 2 1 0 2 2 2 2 Common central domain of tyrosinase Zn_ribbon_recom PF13408.6 KER25311.1 - 0.58 10.7 7.3 13 6.4 0.7 3.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Laminin_EGF PF00053.24 KER25311.1 - 2.1 8.6 32.9 0.1 12.7 1.9 5.5 5 1 0 5 5 5 0 Laminin EGF domain Ribosomal_L31e PF01198.19 KER25312.1 - 1.9e-44 149.8 0.8 2.5e-44 149.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Cadherin PF00028.17 KER25313.1 - 5.1e-72 238.4 0.0 4.4e-17 62.3 0.0 12.7 12 1 0 12 12 12 11 Cadherin domain Cadherin_4 PF17803.1 KER25313.1 - 0.005 17.4 16.8 1.2 9.8 0.0 7.5 7 1 0 7 7 7 3 Bacterial cadherin-like domain Cadherin PF00028.17 KER25314.1 - 0.14 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Cadherin domain Y_Y_Y PF07495.13 KER25314.1 - 0.21 11.5 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain Cadherin PF00028.17 KER25315.1 - 2.1e-64 214.0 2.8 1.9e-14 53.9 0.0 10.2 11 0 0 11 11 11 9 Cadherin domain Cadherin_2 PF08266.12 KER25315.1 - 1.1e-06 28.4 0.0 0.068 13.0 0.0 6.4 9 0 0 9 9 9 1 Cadherin-like Gag_p12 PF01141.18 KER25315.1 - 0.23 11.8 1.7 0.47 10.8 0.1 2.3 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Cadherin PF00028.17 KER25316.1 - 5.7e-34 116.4 0.0 1.2e-12 48.1 0.0 4.2 4 1 0 4 4 4 3 Cadherin domain Cadherin_2 PF08266.12 KER25316.1 - 0.0046 16.8 0.0 0.52 10.2 0.0 3.1 3 0 0 3 3 3 1 Cadherin-like Glyco_transf_64 PF09258.10 KER25317.1 - 0.047 13.0 0.1 0.059 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Cadherin PF00028.17 KER25318.1 - 7e-69 228.3 0.0 4.7e-12 46.2 0.0 9.4 9 0 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 KER25318.1 - 7.3e-07 28.9 0.0 2.2 8.2 0.0 5.9 6 0 0 6 6 6 3 Cadherin-like Cadherin_3 PF16184.5 KER25318.1 - 0.00024 21.1 5.9 0.86 9.6 0.1 5.1 5 0 0 5 5 5 1 Cadherin-like RET_CLD1 PF17756.1 KER25318.1 - 0.0034 17.6 0.0 3.4 8.0 0.0 3.7 4 0 0 4 4 4 1 RET Cadherin like domain 1 DUF5108 PF17133.4 KER25318.1 - 0.0039 17.2 0.1 11 6.0 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF5108) Cadherin PF00028.17 KER25320.1 - 8.8e-27 93.4 0.7 2.7e-11 43.7 0.0 5.7 5 1 0 5 5 5 4 Cadherin domain EGF PF00008.27 KER25320.1 - 1.9e-21 76.0 51.3 1.8e-05 24.9 0.5 7.2 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.7 KER25320.1 - 2.4e-08 34.3 49.5 0.076 13.7 4.1 7.8 6 1 0 6 6 6 5 Human growth factor-like EGF EGF_2 PF07974.13 KER25320.1 - 1.9e-05 24.9 64.1 0.0006 20.1 3.7 6.7 6 0 0 6 6 6 5 EGF-like domain RVT_1 PF00078.27 KER25325.1 - 4.6e-14 52.5 0.1 1.6e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4 PF00105.18 KER25326.1 - 2.9e-29 101.3 13.8 8.6e-29 99.8 13.8 1.9 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER25326.1 - 6.1e-15 55.4 0.2 1.5e-14 54.0 0.2 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nop14 PF04147.12 KER25326.1 - 3 5.9 4.8 4.6 5.3 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.19 KER25330.1 - 1.1e-107 360.2 0.0 7.9e-107 357.4 0.0 1.9 1 1 0 1 1 1 1 Actin Helicase_C_2 PF13307.6 KER25331.1 - 6.7e-48 163.1 0.0 1.8e-47 161.7 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KER25331.1 - 7.2e-36 123.4 1.4 1.9e-35 122.0 1.4 1.8 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KER25331.1 - 0.00098 19.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER25331.1 - 0.0013 19.0 1.1 0.12 12.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain Borrelia_lipo_1 PF05714.11 KER25331.1 - 0.0033 17.2 2.6 0.0063 16.3 2.6 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein DEAD PF00270.29 KER25331.1 - 0.0061 16.3 0.0 0.74 9.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4927 PF16279.5 KER25331.1 - 0.0064 17.5 1.0 0.018 16.0 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4927) PhoH PF02562.16 KER25331.1 - 0.11 11.9 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Spectrin PF00435.21 KER25334.1 - 2.2e-33 114.9 24.9 9.5e-14 51.8 0.2 4.9 4 2 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 KER25334.1 - 6.9e-20 70.9 0.0 2.5e-19 69.1 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 KER25334.1 - 7.6e-09 34.5 0.0 0.00026 20.3 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 KER25334.1 - 9.1e-08 31.4 0.0 0.00037 20.2 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KER25334.1 - 3.7e-06 27.3 1.8 4.5e-05 23.8 0.0 3.4 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 KER25334.1 - 0.00063 19.5 0.0 4.1 7.3 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER25334.1 - 0.07 12.7 0.0 0.38 10.3 0.0 2.4 1 0 0 1 1 1 0 EF hand Erythro-docking PF09277.11 KER25334.1 - 0.073 13.0 0.0 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Erythronolide synthase, docking BLOC1_2 PF10046.9 KER25334.1 - 0.097 13.0 9.3 2.3 8.6 0.1 4.3 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.14 KER25334.1 - 0.11 12.4 5.1 0.8 9.6 1.8 3.2 1 1 1 3 3 3 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.9 KER25334.1 - 3.2 7.8 22.7 0.5 10.4 12.2 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 KER25334.1 - 6.7 7.0 18.0 0.33 11.3 0.2 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) FRG2 PF15315.6 KER25335.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 RRM_1 PF00076.22 KER25336.1 - 3.3e-22 78.1 0.0 2.3e-16 59.4 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER25336.1 - 3e-05 24.1 0.0 0.0013 18.8 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 KER25336.1 - 0.93 9.6 4.4 14 5.8 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif LisH PF08513.11 KER25337.1 - 0.00036 20.4 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 LisH Trp_leader2 PF08056.11 KER25338.1 - 0.16 12.0 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan operon leader peptide RNase_PH_C PF03725.15 KER25339.1 - 5.5e-07 29.5 0.1 7.2e-06 26.0 0.0 2.8 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 KER25339.1 - 4e-06 27.4 0.0 6.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Fer2_2 PF01799.20 KER25339.1 - 0.014 15.4 1.7 5.6 7.1 0.1 2.7 1 1 1 2 2 2 0 [2Fe-2S] binding domain Ribosomal_S30 PF04758.14 KER25341.1 - 2.5e-28 98.0 10.7 3.3e-28 97.7 10.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 DUF3692 PF12469.8 KER25345.1 - 0.047 13.9 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein AAA_33 PF13671.6 KER25350.1 - 3.5e-06 27.2 0.0 7.3e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KER25350.1 - 0.00066 20.2 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER25350.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KER25350.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KER25350.1 - 0.0021 18.6 0.0 0.0048 17.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KER25350.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 KER25350.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KER25350.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 KER25350.1 - 0.039 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KER25350.1 - 0.045 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KER25350.1 - 0.046 13.8 0.0 0.099 12.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2075 PF09848.9 KER25350.1 - 0.046 13.0 0.0 0.071 12.3 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KER25350.1 - 0.054 12.6 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 KER25350.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KER25350.1 - 0.067 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 KER25350.1 - 0.076 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KER25350.1 - 0.092 12.6 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KER25350.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.18 KER25350.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 KER25350.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-C2H2 PF00096.26 KER25351.1 - 0.004 17.5 6.6 0.004 17.5 6.6 5.7 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KER25351.1 - 0.0047 16.6 6.1 0.0047 16.6 6.1 3.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KER25351.1 - 0.025 15.0 12.4 0.57 10.7 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER25351.1 - 0.41 10.7 15.1 0.067 13.2 4.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER25351.1 - 0.48 10.8 7.1 0.88 9.9 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 KER25352.1 - 9.9e-09 35.0 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_6 PF13344.6 KER25353.1 - 2.1e-26 92.0 0.0 6.3e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KER25353.1 - 3.4e-18 65.5 0.0 5.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KER25353.1 - 2.8e-08 34.0 0.5 0.00051 20.2 0.0 3.7 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KER25353.1 - 2.6e-06 27.9 0.0 1.4e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KER25353.1 - 0.0013 18.4 0.1 0.0057 16.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase GIT1_C PF12205.8 KER25354.1 - 4.6e-30 104.1 0.2 4.6e-30 104.1 0.2 1.9 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.11 KER25354.1 - 1.2e-12 47.2 3.4 9.7e-07 28.3 0.0 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF4763 PF15960.5 KER25354.1 - 0.0026 17.1 0.8 0.0066 15.8 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) ATG16 PF08614.11 KER25354.1 - 0.012 15.8 0.5 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BicD PF09730.9 KER25354.1 - 0.022 13.2 1.2 0.036 12.5 1.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Shugoshin_N PF07558.11 KER25354.1 - 0.044 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CALCOCO1 PF07888.11 KER25354.1 - 0.051 12.4 0.6 0.11 11.4 0.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Prefoldin PF02996.17 KER25354.1 - 0.1 12.5 0.7 2.7 7.9 0.3 2.4 2 0 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 KER25354.1 - 0.25 10.2 1.3 0.56 9.0 1.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KER25354.1 - 0.83 10.2 4.7 0.27 11.8 1.1 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4748 PF15932.5 KER25354.1 - 3.5 7.5 4.0 29 4.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4748) DUF1523 PF07509.11 KER25356.1 - 0.066 12.6 0.1 18 4.6 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1523) ING PF12998.7 KER25359.1 - 1.5e-18 67.2 7.0 1.5e-18 67.2 7.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 KER25359.1 - 2.1e-12 47.0 0.2 2.1e-12 47.0 0.2 2.9 2 1 0 2 2 2 1 Swi5 PHD PF00628.29 KER25359.1 - 2.3e-06 27.4 9.2 4.2e-06 26.6 9.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-C4H2 PF10146.9 KER25359.1 - 0.00012 22.5 0.6 0.00012 22.5 0.6 1.6 2 0 0 2 2 2 1 Zinc finger-containing protein Sec2p PF06428.11 KER25359.1 - 0.022 14.7 12.4 0.49 10.4 0.4 3.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Colicin PF01024.19 KER25359.1 - 0.034 14.0 0.3 0.052 13.4 0.3 1.2 1 0 0 1 1 1 0 Colicin pore forming domain PaaA_PaaC PF05138.12 KER25359.1 - 0.04 13.1 1.0 0.075 12.2 1.0 1.4 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Ogr_Delta PF04606.12 KER25359.1 - 0.056 13.4 0.7 0.056 13.4 0.7 2.5 2 1 0 2 2 1 0 Ogr/Delta-like zinc finger DUF3810 PF12725.7 KER25359.1 - 0.082 12.2 0.5 6.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Occludin_ELL PF07303.13 KER25359.1 - 0.21 12.3 8.3 4.1 8.2 0.2 2.6 2 0 0 2 2 2 0 Occludin homology domain Spc7 PF08317.11 KER25359.1 - 0.32 9.8 11.2 0.14 11.0 5.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 KER25359.1 - 0.51 10.6 5.3 3.5 7.9 0.1 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf-C4pol PF14260.6 KER25359.1 - 1.5 9.3 10.5 0.28 11.7 1.4 3.2 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF2203 PF09969.9 KER25359.1 - 1.7 9.3 4.8 2 9.1 1.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 KER25359.1 - 1.9 8.5 6.0 1.7 8.7 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 KER25359.1 - 2.3 7.9 14.1 1.8 8.3 7.5 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B zf-RING-like PF08746.11 KER25359.1 - 3.1 8.2 7.1 6.8 7.1 7.1 1.6 1 0 0 1 1 1 0 RING-like domain CSN5_C PF18323.1 KER25359.1 - 5.1 8.1 6.3 3.7 8.5 3.9 2.1 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain RRF PF01765.19 KER25359.1 - 5.2 7.0 12.3 1.5 8.8 6.4 2.4 2 1 0 2 2 2 0 Ribosome recycling factor DUF1043 PF06295.12 KER25359.1 - 6.1 6.9 8.2 0.77 9.8 2.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) JAB PF01398.21 KER25360.1 - 6.6e-17 61.6 0.3 1.1e-16 60.8 0.3 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Vps52 PF04129.12 KER25362.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family Tipalpha PF16753.5 KER25365.1 - 0.009 15.8 0.0 0.029 14.2 0.0 1.7 2 0 0 2 2 2 1 TNF-alpha-Inducing protein of Helicobacter DnaJ PF00226.31 KER25366.1 - 2.6e-23 81.9 0.0 7.7e-23 80.4 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain HpcH_HpaI PF03328.14 KER25368.1 - 1e-26 93.5 0.0 1.5e-16 60.2 0.0 3.2 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KER25368.1 - 0.00034 19.9 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold RVT_1 PF00078.27 KER25368.1 - 0.0076 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cript PF10235.9 KER25369.1 - 1.2e-31 109.1 3.7 1.2e-31 109.1 3.7 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 KER25369.1 - 0.0038 17.5 5.6 0.0038 17.5 5.6 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Gin PF10764.9 KER25369.1 - 0.17 11.9 6.7 2.7 8.0 0.1 2.9 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.7 KER25369.1 - 0.45 10.6 11.8 2 8.5 7.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KER25369.1 - 2.3 8.3 10.7 3.7 7.6 6.4 2.4 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KER25369.1 - 3.1 8.6 13.7 25 5.7 0.4 2.8 2 1 0 2 2 2 0 zinc-ribbon family C1_2 PF03107.16 KER25369.1 - 3.1 8.2 13.4 0.71 10.2 7.7 2.6 2 1 1 3 3 3 0 C1 domain PHF5 PF03660.14 KER25369.1 - 6.8 6.9 13.0 1.8 8.8 8.4 2.3 2 1 0 2 2 2 0 PHF5-like protein Vac14_Fig4_bd PF11916.8 KER25370.1 - 1.7e-61 207.0 4.1 3.5e-61 206.0 4.1 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KER25370.1 - 2.5e-34 117.7 0.0 3.6e-31 107.6 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KER25370.1 - 2.3e-11 42.9 3.8 0.005 17.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KER25370.1 - 2.6e-07 31.0 0.2 0.75 10.4 0.0 5.1 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KER25370.1 - 2.1e-06 28.0 0.2 0.2 12.0 0.0 4.2 2 1 1 4 4 4 2 HEAT repeats Tti2 PF10521.9 KER25370.1 - 0.00015 21.5 0.9 0.35 10.4 0.0 3.5 3 0 0 3 3 3 1 Tti2 family Cnd1 PF12717.7 KER25370.1 - 0.00036 20.6 0.1 1.8 8.6 0.0 3.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KER25370.1 - 0.00059 20.0 0.0 0.066 13.4 0.0 3.5 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KER25370.1 - 0.0012 17.6 0.0 0.031 12.8 0.0 2.4 2 1 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 KER25370.1 - 0.004 16.7 0.0 1.5 8.3 0.0 3.6 3 0 0 3 3 3 1 CLASP N terminal Cohesin_HEAT PF12765.7 KER25370.1 - 0.0045 17.3 0.2 0.036 14.4 0.1 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 KER25370.1 - 0.011 15.7 0.0 4.2 7.5 0.1 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 KER25370.1 - 0.036 14.4 0.9 0.37 11.2 0.1 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain IMPDH PF00478.25 KER25370.1 - 0.084 11.9 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Arfaptin PF06456.13 KER25374.1 - 5.5e-39 134.1 6.6 1.2e-22 80.7 3.0 3.0 1 1 1 2 2 2 2 Arfaptin-like domain PDZ_6 PF17820.1 KER25374.1 - 2.6e-07 30.4 0.0 6.7e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER25374.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER25374.1 - 2.4e-06 27.8 0.0 6.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain BAR PF03114.18 KER25374.1 - 8.3e-05 22.3 1.8 0.00046 19.9 0.3 2.1 2 0 0 2 2 2 1 BAR domain BAR_3 PF16746.5 KER25374.1 - 0.0037 17.0 1.8 0.084 12.6 0.3 2.2 1 1 1 2 2 2 1 BAR domain of APPL family Mt_ATP-synt_D PF05873.12 KER25375.1 - 1.3e-33 116.0 0.1 1.5e-33 115.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Snf7 PF03357.21 KER25375.1 - 0.008 15.8 1.1 0.012 15.2 1.1 1.3 1 0 0 1 1 1 1 Snf7 KELK PF15796.5 KER25375.1 - 0.053 14.0 0.8 0.12 12.9 0.8 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase V-SNARE_C PF12352.8 KER25375.1 - 0.054 13.8 0.2 0.35 11.2 0.2 2.2 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CREPT PF16566.5 KER25375.1 - 0.086 13.0 0.4 0.39 10.9 0.2 1.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DEAD PF00270.29 KER25376.1 - 5.2e-13 49.1 0.0 3.6e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER25376.1 - 2.1e-12 47.3 0.0 3.8e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER25376.1 - 2.2e-07 31.1 0.0 4.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KER25376.1 - 0.00089 19.8 0.0 0.0039 17.7 0.0 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KER25376.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 KER25376.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus 2OG-FeII_Oxy_3 PF13640.6 KER25379.1 - 7.2e-17 62.1 0.0 1.6e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KER25379.1 - 5.6e-11 43.0 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KER25379.1 - 0.043 14.3 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CID_GANP PF16766.5 KER25379.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Binding region of GANP to ENY2 Tubulin PF00091.25 KER25380.1 - 2.2e-68 230.4 0.0 3.5e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25380.1 - 2.9e-43 147.0 0.1 4.6e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER25380.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KER25380.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KER25380.1 - 0.023 13.9 0.1 0.047 12.9 0.0 1.5 2 0 0 2 2 2 0 Tubulin like HEAT PF02985.22 KER25381.1 - 3.2e-19 67.3 7.6 0.013 15.7 0.0 9.4 9 0 0 9 9 8 4 HEAT repeat HEAT_EZ PF13513.6 KER25381.1 - 4.3e-11 43.1 3.0 0.025 15.1 0.0 8.8 6 2 6 12 12 12 3 HEAT-like repeat IBN_N PF03810.19 KER25381.1 - 1.9e-10 40.5 0.0 1.6e-09 37.6 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KER25381.1 - 7.3e-10 39.1 0.0 0.18 12.2 0.0 5.7 5 2 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KER25381.1 - 1.1e-09 38.5 0.0 0.021 14.9 0.1 3.4 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KER25381.1 - 9.8e-09 35.0 2.3 0.027 14.5 0.0 6.2 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KER25381.1 - 1.6e-07 30.3 0.1 0.0069 15.0 0.0 3.5 3 1 1 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KER25381.1 - 3.2e-06 27.6 0.2 0.0012 19.4 0.1 4.3 4 2 3 7 7 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KER25381.1 - 6.1e-05 22.7 0.7 1.7 8.1 0.2 4.1 2 2 2 4 4 4 3 CLASP N terminal MMS19_C PF12460.8 KER25381.1 - 0.00042 19.6 0.0 0.069 12.3 0.0 3.5 2 1 2 4 4 4 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KER25381.1 - 0.009 16.2 0.2 4 7.6 0.0 3.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 KER25381.1 - 0.033 12.7 0.0 0.097 11.2 0.0 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 KER25381.1 - 0.037 13.1 0.0 1.1 8.3 0.0 2.6 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KER25381.1 - 0.06 13.3 0.1 0.43 10.5 0.1 2.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF1981 PF09324.10 KER25381.1 - 0.14 12.1 0.0 24 4.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1981) Smr PF01713.21 KER25382.1 - 1.3e-06 28.6 0.0 6.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Smr domain zf-RanBP PF00641.18 KER25383.1 - 2.5e-07 29.9 6.0 4e-07 29.2 6.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RhoGAP PF00620.27 KER25384.1 - 6.6e-39 133.2 0.3 1.6e-38 131.9 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 KER25384.1 - 6.5e-36 124.2 9.7 1.5e-35 123.1 9.7 1.6 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KER25384.1 - 4.5e-07 30.3 0.1 1.2e-06 29.0 0.1 1.7 1 0 0 1 1 1 1 PH domain BLOC1S3 PF15753.5 KER25384.1 - 0.0023 18.1 0.3 0.0064 16.6 0.3 1.8 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 YolD PF08863.10 KER25384.1 - 0.06 13.4 0.4 0.17 11.9 0.4 1.7 1 0 0 1 1 1 0 YolD-like protein TIP120 PF08623.10 KER25384.1 - 0.13 12.1 1.5 0.28 11.0 1.0 1.8 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) KxDL PF10241.9 KER25384.1 - 0.14 12.5 4.8 4.6 7.6 2.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF327 PF03885.13 KER25384.1 - 0.2 11.6 7.2 0.67 9.9 7.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Synaphin PF05835.12 KER25385.1 - 1.2e-19 70.9 0.6 1.8e-19 70.5 0.6 1.2 1 0 0 1 1 1 1 Synaphin protein DUF2226 PF09987.9 KER25385.1 - 0.02 14.3 0.8 0.025 14.0 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Cupin_2 PF07883.11 KER25386.1 - 4.3e-13 48.8 0.1 5.5e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KER25386.1 - 3.2e-06 27.1 0.0 4.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 KER25386.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family EutQ PF06249.12 KER25386.1 - 0.029 14.2 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_4 PF08007.12 KER25386.1 - 0.083 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein GTP_EFTU PF00009.27 KER25387.1 - 4.9e-54 182.8 0.0 7e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KER25387.1 - 4.4e-41 139.7 0.0 1e-40 138.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KER25387.1 - 5e-15 55.7 1.0 1.1e-14 54.5 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KER25387.1 - 0.00054 20.0 0.1 0.016 15.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KER25387.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.7 3 0 0 3 3 3 0 Elongation factor Tu domain 4 OB_NTP_bind PF07717.16 KER25388.1 - 2.1e-24 85.7 0.0 5.1e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KER25388.1 - 1.7e-18 66.8 6.0 6e-15 55.5 0.1 3.6 4 0 0 4 4 3 2 Helicase associated domain (HA2) TPR_11 PF13414.6 KER25388.1 - 7.7e-15 54.3 6.2 2.6e-09 36.6 0.2 4.1 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.28 KER25388.1 - 5.2e-14 51.4 9.9 5.9e-08 32.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Helicase_C PF00271.31 KER25388.1 - 1.3e-13 51.2 0.0 5.5e-13 49.2 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain TPR_2 PF07719.17 KER25388.1 - 1e-12 47.1 8.0 4.9e-05 23.1 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER25388.1 - 3.3e-11 42.5 6.0 0.0001 22.2 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER25388.1 - 1.9e-10 41.1 6.6 1.7e-05 25.2 0.9 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER25388.1 - 4.9e-10 39.6 3.2 6.4e-06 26.4 1.4 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat S1 PF00575.23 KER25388.1 - 2.9e-09 37.2 0.2 5.9e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain TPR_17 PF13431.6 KER25388.1 - 5.3e-08 32.7 7.9 0.014 15.7 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER25388.1 - 1.2e-07 32.0 4.2 0.044 14.6 0.0 5.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER25388.1 - 1.4e-07 32.1 9.7 0.00062 20.4 1.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat DEAD PF00270.29 KER25388.1 - 1e-06 28.7 0.1 4e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TPR_10 PF13374.6 KER25388.1 - 3.1e-06 26.9 14.9 0.0041 17.0 0.1 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 KER25388.1 - 8.9e-05 22.8 0.1 0.00076 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KER25388.1 - 0.00017 21.4 6.7 0.08 13.0 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_19 PF13245.6 KER25388.1 - 0.0011 19.3 0.2 0.0043 17.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KER25388.1 - 0.006 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KER25388.1 - 0.0069 15.5 0.1 0.017 14.2 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NARP1 PF12569.8 KER25388.1 - 0.01 14.8 0.2 0.01 14.8 0.2 2.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 KER25388.1 - 0.024 15.2 3.8 20 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_RecD PF05127.14 KER25388.1 - 0.041 13.7 1.0 1.2 8.9 0.0 3.4 3 1 1 4 4 4 0 Helicase TPR_9 PF13371.6 KER25388.1 - 0.047 13.8 0.3 9.8 6.4 0.0 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER25388.1 - 0.05 13.7 0.1 0.2 11.7 0.1 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KER25388.1 - 0.092 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 SHNi-TPR DUF2075 PF09848.9 KER25388.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3896 PF13035.6 KER25388.1 - 0.15 12.2 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) MITF_TFEB_C_3_N PF15951.5 KER25388.1 - 2.4 8.8 7.2 8.6 7.0 7.2 1.9 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus FDC-SP PF15215.6 KER25390.1 - 0.002 18.6 2.8 0.0037 17.8 2.8 1.4 1 0 0 1 1 1 1 Follicular dendritic cell secreted peptide Trypsin PF00089.26 KER25391.1 - 1.4e-38 132.9 0.0 2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KER25391.1 - 0.0057 17.6 0.1 0.016 16.1 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C2 PF00648.21 KER25392.1 - 4.1e-116 387.2 0.0 5.8e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KER25392.1 - 1.6e-39 135.4 0.0 2.8e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KER25392.1 - 2.1e-07 30.0 0.0 0.0032 16.9 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KER25392.1 - 1e-06 28.2 0.3 0.00068 19.4 0.0 3.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KER25392.1 - 1.1e-05 25.1 0.0 0.00025 20.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 KER25392.1 - 2.2e-05 24.8 6.6 0.0036 17.7 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair AvrB_AvrC PF05394.11 KER25392.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Avirulence protein COesterase PF00135.28 KER25394.1 - 5.9e-143 477.4 0.0 7.6e-143 477.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER25394.1 - 2.2e-07 30.9 0.1 5.4e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KER25394.1 - 0.051 13.0 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family rve_3 PF13683.6 KER25395.1 - 0.11 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Calponin PF00402.18 KER25397.1 - 1.2e-62 207.1 47.1 1e-12 47.4 3.5 5.6 5 0 0 5 5 5 5 Calponin family repeat CH PF00307.31 KER25397.1 - 7.3e-20 71.2 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Beta-APP PF03494.13 KER25397.1 - 0.22 11.4 6.6 11 6.0 0.3 3.8 4 0 0 4 4 4 0 Beta-amyloid peptide (beta-APP) Ras PF00071.22 KER25398.1 - 2.3e-25 89.1 0.1 5.6e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KER25398.1 - 0.00024 21.3 0.0 0.00068 19.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KER25398.1 - 0.093 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter zf-DBF PF07535.12 KER25399.1 - 2.6e-16 59.5 1.7 4.6e-16 58.6 1.7 1.4 1 0 0 1 1 1 1 DBF zinc finger CTD_bind PF04818.13 KER25401.1 - 1.3e-09 38.8 0.1 3.6e-08 34.1 0.1 2.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 KER25401.1 - 0.053 13.7 3.0 0.15 12.2 3.0 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour O-FucT PF10250.9 KER25402.1 - 4.1e-51 174.7 0.0 5.4e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 KER25402.1 - 0.042 13.1 0.0 0.23 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 11 Bclx_interact PF08945.10 KER25402.1 - 0.13 12.0 1.7 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain DUF5401 PF17380.2 KER25403.1 - 0.2 9.7 8.5 0.24 9.4 8.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Membr_traf_MHD PF10540.9 KER25404.1 - 7.4e-43 146.3 1.0 2.5e-42 144.5 1.0 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 KER25404.1 - 9.8e-31 106.3 8.0 3.1e-30 104.7 0.2 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) C2 PF00168.30 KER25404.1 - 1.9e-21 76.3 5.2 7.5e-15 55.1 0.1 3.1 3 0 0 3 3 3 2 C2 domain C1_1 PF00130.22 KER25404.1 - 4.7e-11 42.4 5.9 9.4e-11 41.4 5.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) T3SS_ATPase_C PF18269.1 KER25404.1 - 0.023 14.5 0.9 11 6.0 0.1 2.7 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain TipAS PF07739.13 KER25404.1 - 0.13 12.8 1.5 28 5.3 0.2 3.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain zf-RING-like PF08746.11 KER25404.1 - 0.57 10.5 4.3 2.3 8.6 4.3 2.1 1 0 0 1 1 1 0 RING-like domain Tubulin PF00091.25 KER25407.1 - 3.6e-65 219.9 0.0 5.3e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25407.1 - 5e-33 114.0 0.4 9.9e-33 113.0 0.4 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER25407.1 - 1.5e-05 25.3 0.0 3.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KER25407.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Bcl-2 PF00452.19 KER25409.1 - 3.5e-15 56.5 1.1 2.7e-14 53.7 0.3 2.3 1 1 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family C2 PF00168.30 KER25410.1 - 0.00072 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain DBD_HTH PF18430.1 KER25410.1 - 3.3 7.6 4.4 18 5.2 0.6 2.5 2 0 0 2 2 2 0 Putative DNA-binding domain GST_N_4 PF17172.4 KER25411.1 - 0.082 13.7 0.0 0.09 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Pkinase PF00069.25 KER25413.1 - 9e-33 113.8 0.0 9.7e-26 90.7 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER25413.1 - 5.9e-13 48.7 0.0 4.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_38N PF01074.22 KER25414.1 - 5.2e-85 285.3 2.5 7.5e-85 284.8 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KER25414.1 - 7.5e-27 94.8 0.0 1.7e-26 93.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KER25414.1 - 3e-19 69.0 1.3 2.2e-18 66.2 0.3 2.4 2 0 0 2 2 2 1 Alpha mannosidase middle domain Tubulin PF00091.25 KER25416.1 - 1.7e-60 204.6 0.0 2.4e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER25416.1 - 1.6e-42 144.6 0.0 2.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER25416.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain BDV_P10 PF06515.11 KER25417.1 - 0.037 14.1 0.3 0.056 13.5 0.2 1.5 1 1 0 1 1 1 0 Borna disease virus P10 protein ECH_1 PF00378.20 KER25418.1 - 1e-57 195.4 0.0 1.2e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER25418.1 - 2e-17 63.7 1.4 7.9e-13 48.6 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KER25418.1 - 0.011 15.7 0.1 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 MFS_1 PF07690.16 KER25424.1 - 2e-28 99.4 8.2 1.7e-27 96.3 4.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0004 PF00919.20 KER25425.1 - 1.2e-14 54.2 0.0 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KER25425.1 - 5.5e-11 43.1 0.1 5.7e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 KER25425.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 TRAM domain Ycf9 PF01737.17 KER25426.1 - 0.031 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 YCF9 Forkhead PF00250.18 KER25427.1 - 1.2e-24 86.4 0.1 2.4e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Ank_2 PF12796.7 KER25428.1 - 1.4e-41 140.9 8.7 1.3e-14 54.5 1.0 3.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER25428.1 - 1.5e-27 92.5 4.7 1.3e-05 25.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KER25428.1 - 1.8e-27 94.5 6.8 3.1e-06 27.4 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KER25428.1 - 4.4e-26 90.6 8.5 4.9e-07 29.9 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER25428.1 - 7.3e-26 90.2 8.7 1.9e-11 44.2 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) RVP PF00077.20 KER25428.1 - 0.1 12.9 0.0 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Glyco_hydro_38N PF01074.22 KER25429.1 - 3.8e-99 331.7 5.9 3.2e-56 190.8 0.9 2.7 3 0 0 3 3 3 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KER25429.1 - 3.2e-24 84.9 0.1 7.2e-24 83.8 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 KER25429.1 - 1.9e-14 54.2 0.0 4.9e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF3047 PF11249.8 KER25429.1 - 0.021 14.2 0.2 9.1 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3047) XisI PF08869.11 KER25429.1 - 0.086 13.2 0.0 32 4.9 0.0 2.8 2 0 0 2 2 2 0 XisI protein DUF1735 PF08522.10 KER25429.1 - 0.12 13.0 0.1 33 5.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) Glyco_hydro_38C PF07748.13 KER25430.1 - 7.9e-25 88.2 0.0 8.8e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 KER25431.1 - 6e-73 245.7 0.3 8.5e-73 245.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 KER25431.1 - 3e-15 56.2 0.4 7.7e-14 51.6 0.6 2.9 2 1 0 2 2 2 1 Alpha mannosidase middle domain PH PF00169.29 KER25435.1 - 1.6e-08 35.0 0.0 2.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KER25435.1 - 0.013 15.8 0.1 0.03 14.6 0.1 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KER25435.1 - 0.016 15.6 0.0 7.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Tektin PF03148.14 KER25437.1 - 4.7e-91 305.4 35.6 5.3e-91 305.2 35.6 1.0 1 0 0 1 1 1 1 Tektin family Retrotrans_gag PF03732.17 KER25437.1 - 0.081 13.2 5.4 0.74 10.1 1.6 3.8 4 1 0 4 4 4 0 Retrotransposon gag protein DUF4650 PF15509.6 KER25437.1 - 0.13 11.6 3.2 0.22 10.8 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Phos_pyr_kin PF08543.12 KER25437.1 - 0.14 11.5 0.5 0.29 10.5 0.5 1.5 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase COG5 PF10392.9 KER25437.1 - 0.29 11.3 7.9 4.3 7.5 0.2 3.5 3 1 1 4 4 4 0 Golgi transport complex subunit 5 DUF2408 PF10303.9 KER25437.1 - 2.5 8.7 16.5 0.36 11.4 5.9 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.8 KER25437.1 - 6 7.0 15.5 0.59 10.2 0.2 4.2 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 KER25437.1 - 7.5 6.9 9.2 1.5 9.2 0.1 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Carn_acyltransf PF00755.20 KER25438.1 - 5.4e-164 547.1 0.0 2.3e-85 287.4 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase CPT_N PF16484.5 KER25438.1 - 5.7e-17 61.4 0.7 1.7e-16 59.9 0.7 1.9 1 0 0 1 1 1 1 Carnitine O-palmitoyltransferase N-terminus UPF0004 PF00919.20 KER25439.1 - 0.084 12.9 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF727 PF05303.12 KER25441.1 - 4.3e-29 100.7 0.1 5.8e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DUF4336 PF14234.6 KER25442.1 - 0.018 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) UPF0767 PF15990.5 KER25443.1 - 2.3e-17 62.9 0.0 2.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 UPF0767 family TspO_MBR PF03073.15 KER25444.1 - 4.2e-65 217.9 27.2 8.2e-42 142.5 12.3 2.1 2 0 0 2 2 2 2 TspO/MBR family CcmF_C PF16327.5 KER25444.1 - 6.8 5.9 14.7 0.7 9.1 1.7 2.4 3 0 0 3 3 3 0 Cytochrome c-type biogenesis protein CcmF C-terminal Shisa PF13908.6 KER25446.1 - 5.8 7.1 13.8 1 9.6 6.1 3.0 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator ADH_zinc_N_2 PF13602.6 KER25447.1 - 6.6e-13 49.9 0.0 2.7e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KER25447.1 - 2.1e-12 46.9 0.3 2.1e-12 46.9 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KER25447.1 - 6.8e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_C62 PF12380.8 KER25447.1 - 0.0082 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Gill-associated viral 3C-like peptidase DUF442 PF04273.13 KER25447.1 - 0.11 12.6 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative phosphatase (DUF442) BROMI PF14961.6 KER25449.1 - 2.7e-54 184.2 0.3 1.6e-37 128.6 0.0 3.9 4 0 0 4 4 4 4 Broad-minded protein DUF1179 PF06678.11 KER25449.1 - 2.1 8.4 6.2 14 5.7 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1179) NOG1_N PF17835.1 KER25450.1 - 3.1e-52 176.8 0.3 3.1e-52 176.8 0.3 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KER25450.1 - 3.2e-25 87.7 0.1 6.7e-25 86.6 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KER25450.1 - 4.2e-18 65.5 0.0 9.1e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 KER25450.1 - 2e-16 59.7 2.5 2e-16 59.7 0.3 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.18 KER25450.1 - 1.8e-10 40.6 0.0 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KER25450.1 - 0.0013 18.8 0.1 1.1 9.3 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KER25450.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 KER25450.1 - 0.062 13.2 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase DUF4113 PF13438.6 KER25450.1 - 0.59 10.3 2.1 0.55 10.4 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) Tetraspanin PF00335.20 KER25452.1 - 2.1e-17 63.6 16.4 3.2e-17 63.0 16.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1269 PF06897.12 KER25452.1 - 0.32 11.3 1.6 0.38 11.1 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) PHO4 PF01384.20 KER25452.1 - 0.34 9.9 2.4 2.3 7.2 0.1 2.2 2 0 0 2 2 2 0 Phosphate transporter family DUF948 PF06103.11 KER25452.1 - 8.3 6.7 10.2 0.28 11.5 1.5 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 KER25453.1 - 8.6e-47 157.7 8.5 4.4e-13 49.6 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER25453.1 - 2e-40 136.3 6.2 9.7e-09 35.3 0.0 8.3 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER25453.1 - 1.1e-34 118.4 5.9 1.3e-10 41.6 0.0 8.3 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER25453.1 - 1.4e-33 111.1 5.5 0.00012 22.3 0.0 10.7 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 KER25453.1 - 6.7e-29 99.1 7.9 4.2e-05 23.8 0.0 9.5 10 0 0 10 10 10 6 Ankyrin repeat Death PF00531.22 KER25453.1 - 2.1e-06 27.8 1.4 7e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 Death domain BORCS8 PF10167.9 KER25454.1 - 3.5e-22 78.4 0.0 3.2e-17 62.5 0.0 2.6 3 0 0 3 3 3 2 BLOC-1-related complex sub-unit 8 ADAM_CR PF08516.12 KER25455.1 - 7.3e-16 58.6 6.2 7.3e-16 58.6 6.2 5.0 6 0 0 6 6 6 1 ADAM cysteine-rich Disintegrin PF00200.23 KER25455.1 - 5.3e-15 56.0 17.7 5.3e-15 56.0 17.7 6.9 7 2 0 7 7 7 1 Disintegrin Pep_M12B_propep PF01562.19 KER25455.1 - 2.4e-11 44.0 0.0 2.4e-11 44.0 0.0 2.9 3 0 0 3 3 3 1 Reprolysin family propeptide Reprolysin PF01421.19 KER25455.1 - 1e-08 35.3 0.7 3.2e-06 27.2 0.0 2.7 3 0 0 3 3 3 2 Reprolysin (M12B) family zinc metalloprotease ox_reductase_C PF08635.10 KER25457.1 - 0.1 12.2 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain MORN PF02493.20 KER25461.1 - 8.2e-38 126.1 37.9 1.1e-06 28.1 0.3 7.4 7 0 0 7 7 7 7 MORN repeat MORN_2 PF07661.13 KER25461.1 - 0.88 10.0 0.1 0.88 10.0 0.1 4.7 5 1 0 5 5 5 0 MORN repeat variant Zip PF02535.22 KER25462.1 - 4.9 6.3 4.3 4.7 6.3 4.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Asp PF00026.23 KER25463.1 - 1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER25463.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal BAALC_N PF06989.12 KER25463.1 - 0.11 12.9 0.3 0.17 12.2 0.3 1.3 1 0 0 1 1 1 0 BAALC N-terminus Defensin_1 PF00323.19 KER25463.1 - 0.16 12.6 0.1 0.3 11.7 0.1 1.4 1 0 0 1 1 1 0 Mammalian defensin Asp PF00026.23 KER25464.1 - 2.9e-12 46.7 0.0 3.3e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER25464.1 - 0.00011 22.0 0.1 0.00012 21.8 0.1 1.0 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4446 PF14584.6 KER25465.1 - 0.1 12.6 0.4 0.19 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Laminin_G_2 PF02210.24 KER25466.1 - 6.5e-73 243.3 2.2 3.5e-16 59.9 0.1 7.0 7 0 0 7 7 7 6 Laminin G domain Laminin_G_1 PF00054.23 KER25466.1 - 8.1e-54 181.4 0.0 1.2e-14 54.6 0.0 7.3 7 1 0 7 7 7 6 Laminin G domain EGF PF00008.27 KER25466.1 - 6.8e-31 106.2 299.7 7.3e-05 23.0 9.3 18.1 18 0 0 18 18 18 16 EGF-like domain WD40 PF00400.32 KER25466.1 - 1.6e-15 57.2 5.9 1.3e-08 35.3 0.2 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 KER25466.1 - 0.0027 17.1 0.0 0.0065 15.8 0.0 1.6 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 KER25466.1 - 0.032 12.9 0.0 0.11 11.1 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DP PF08781.10 KER25467.1 - 1.4e-21 76.8 0.0 2.1e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 KER25467.1 - 0.0035 17.3 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Mucin-like PF16058.5 KER25467.1 - 0.45 10.6 5.1 1.6 8.9 5.1 1.9 1 1 0 1 1 1 0 Mucin-like E1-E2_ATPase PF00122.20 KER25468.1 - 6.2e-45 152.9 2.9 1.2e-44 152.0 1.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KER25468.1 - 1.4e-34 119.4 0.0 1.4e-34 119.4 0.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KER25468.1 - 2.6e-23 81.9 0.0 4.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KER25468.1 - 4.1e-20 73.0 0.0 8.3e-11 42.6 0.0 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KER25468.1 - 1.6e-19 69.3 0.0 3.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RVT_1 PF00078.27 KER25468.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD PF12710.7 KER25468.1 - 0.046 14.1 0.1 0.41 11.0 0.1 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KER25469.1 - 1.8e-71 236.7 20.6 5.3e-13 49.4 0.4 7.5 4 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER25469.1 - 1.5e-52 174.9 22.5 2.3e-08 34.2 0.4 12.2 7 2 6 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER25469.1 - 2.3e-51 171.5 19.7 7.2e-08 32.8 0.1 11.7 4 4 6 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER25469.1 - 4.9e-45 146.3 22.4 0.0016 18.8 0.0 14.5 15 0 0 15 15 15 10 Ankyrin repeat Ank PF00023.30 KER25469.1 - 4.6e-44 147.0 33.2 0.0047 17.3 0.0 14.4 14 0 0 14 14 14 11 Ankyrin repeat SOCS_box PF07525.16 KER25469.1 - 6e-09 36.1 0.4 1.6e-08 34.7 0.4 1.8 1 0 0 1 1 1 1 SOCS box SARAF PF06682.12 KER25469.1 - 0.92 9.1 4.7 20 4.7 0.0 2.9 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis LRR_4 PF12799.7 KER25470.1 - 4.3e-11 42.9 11.6 0.00022 21.5 1.7 4.9 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER25470.1 - 2.3e-08 33.7 0.0 0.015 14.8 0.0 3.6 3 1 0 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 KER25470.1 - 0.00049 19.8 0.1 0.00049 19.8 0.1 4.2 4 2 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 KER25470.1 - 0.033 14.2 4.5 15 6.0 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich repeat ubiquitin PF00240.23 KER25470.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family LRR_1 PF00560.33 KER25470.1 - 0.24 12.1 9.6 1.5 9.6 0.3 4.7 2 2 1 3 3 3 0 Leucine Rich Repeat MM_CoA_mutase PF01642.22 KER25472.1 - 3.1e-231 768.4 8.4 1.6e-230 766.0 8.4 1.8 1 1 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KER25472.1 - 5e-16 58.8 0.2 1.2e-15 57.6 0.2 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 KER25472.1 - 0.19 11.9 1.7 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 HisG, C-terminal domain DASH_Dam1 PF08653.10 KER25475.1 - 0.32 10.8 0.9 1.7 8.5 0.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Actin PF00022.19 KER25476.1 - 6.5e-90 301.7 0.0 1.2e-87 294.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KER25476.1 - 6e-06 25.3 0.0 0.007 15.2 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KER25476.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Peptidase_C65 PF10275.9 KER25477.1 - 7e-70 235.3 0.0 8.4e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain CSD PF00313.22 KER25478.1 - 1.8e-26 91.8 0.4 1.8e-26 91.8 0.4 1.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain S1 PF00575.23 KER25478.1 - 0.0028 18.0 0.2 0.0048 17.2 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain eIF2A PF08662.11 KER25481.1 - 5.8e-38 130.7 0.1 7.1e-19 68.4 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SRF-TF PF00319.18 KER25482.1 - 3.6e-16 58.4 0.1 6.4e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PP1 PF07430.11 KER25484.1 - 0.0026 17.8 0.9 1.1 9.4 0.1 2.3 1 1 1 2 2 2 2 Phloem filament protein PP1 cystatin-like domain Herpes_UL14 PF03580.14 KER25484.1 - 0.0072 16.6 0.1 4.3 7.6 0.0 2.1 1 1 1 2 2 2 2 Herpesvirus UL14-like protein Phage_min_tail PF05939.13 KER25484.1 - 0.068 13.6 0.0 16 5.9 0.0 2.3 1 1 1 2 2 2 0 Phage minor tail protein DnaI_N PF07319.11 KER25484.1 - 0.084 13.5 0.0 17 6.2 0.1 2.2 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus HEAT PF02985.22 KER25485.1 - 4.9e-06 26.3 0.9 12 6.5 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KER25485.1 - 0.00011 22.5 1.0 0.76 10.2 0.0 5.4 6 0 0 6 6 6 1 HEAT repeats Inhibitor_I78 PF11720.8 KER25485.1 - 0.19 11.8 0.5 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Peptidase inhibitor I78 family CLASP_N PF12348.8 KER25487.1 - 0.046 13.3 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal Prefoldin PF02996.17 KER25491.1 - 1.5e-25 89.4 0.4 1.8e-25 89.2 0.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DEDD_Tnp_IS110 PF01548.17 KER25491.1 - 0.00062 19.7 1.4 0.52 10.2 0.2 2.1 2 0 0 2 2 2 2 Transposase Prefoldin_2 PF01920.20 KER25491.1 - 0.0048 16.8 2.4 0.52 10.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit ING PF12998.7 KER25491.1 - 0.0093 16.5 1.2 0.1 13.2 0.1 2.2 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding BORCS7 PF16088.5 KER25491.1 - 0.044 14.0 4.1 0.057 13.7 0.9 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 KER25491.1 - 0.049 13.7 0.6 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KER25491.1 - 0.057 13.5 3.0 0.071 13.2 0.2 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 KER25491.1 - 0.058 13.6 2.9 4.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1759 PF03564.15 KER25491.1 - 0.086 12.8 0.2 2 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4703 PF15775.5 KER25492.1 - 0.95 9.2 7.0 1.9 8.3 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Cyclin PF08613.11 KER25493.1 - 8.6e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin COesterase PF00135.28 KER25496.1 - 5.6e-05 22.2 0.1 6.4e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KER25497.1 - 1.3e-116 390.5 0.0 1.7e-116 390.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER25497.1 - 2.6e-05 24.2 0.6 0.00019 21.4 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Tetraspanin PF00335.20 KER25500.1 - 3.7e-35 121.7 11.8 4e-35 121.6 11.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2976 PF11190.8 KER25500.1 - 0.0019 18.0 0.2 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) RSN1_7TM PF02714.15 KER25500.1 - 0.11 11.8 6.7 0.063 12.6 1.1 2.1 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate DUF1189 PF06691.11 KER25500.1 - 0.5 9.9 4.7 9.8 5.7 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) TssN PF17555.2 KER25500.1 - 3.8 6.8 9.4 0.45 9.9 2.4 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF2207 PF09972.9 KER25500.1 - 8.1 5.1 9.1 0.25 10.1 2.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ras PF00071.22 KER25501.1 - 8.3e-55 184.8 0.0 9.5e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER25501.1 - 2.4e-34 118.1 0.0 3.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER25501.1 - 7.9e-12 45.0 0.0 9.3e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER25501.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KER25501.1 - 0.0013 18.1 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KER25501.1 - 0.008 16.1 0.1 0.7 9.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KER25501.1 - 0.058 13.8 0.1 0.11 12.9 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 KER25501.1 - 0.061 12.7 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SH2 PF00017.24 KER25502.1 - 1.2e-08 34.9 0.0 4.4e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 SH2 domain ABC2_membrane PF01061.24 KER25505.1 - 8.6e-42 142.9 28.4 8.6e-42 142.9 28.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KER25505.1 - 6.4e-28 98.0 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER25505.1 - 5.9e-08 32.4 0.0 9.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KER25505.1 - 7.8e-07 29.2 0.0 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KER25505.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KER25505.1 - 0.022 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 KER25505.1 - 0.06 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 KER25505.1 - 0.065 13.5 0.0 0.64 10.3 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KER25505.1 - 0.12 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KER25505.1 - 0.17 12.3 0.1 0.37 11.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KER25505.1 - 0.18 10.4 0.0 1.5 7.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Integrase_H2C2 PF17921.1 KER25506.1 - 1.4e-12 47.5 3.6 2.7e-12 46.6 3.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KER25506.1 - 4.3e-09 36.6 0.0 2.3e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KER25506.1 - 0.017 15.2 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve_3 PF13683.6 KER25506.1 - 0.027 14.2 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.10 KER25506.1 - 0.036 14.3 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Asp PF00026.23 KER25507.1 - 8.2e-17 61.6 0.0 4.7e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease NMT PF01233.19 KER25509.1 - 1.8e-40 138.4 0.0 3.5e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KER25509.1 - 6.4e-39 133.7 5.0 3.6e-20 72.4 0.5 3.1 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Asp PF00026.23 KER25509.1 - 1.4e-19 70.7 0.2 1.8e-19 70.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER25509.1 - 1.1e-08 35.5 0.0 2.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Ank_2 PF12796.7 KER25510.1 - 1e-24 86.9 0.1 1.6e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER25510.1 - 1.4e-20 72.8 0.1 2.4e-07 30.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KER25510.1 - 2.4e-20 72.3 0.5 4.9e-09 36.3 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER25510.1 - 1.8e-18 64.7 0.1 0.00015 21.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KER25510.1 - 8.3e-18 64.5 0.2 7.3e-08 32.8 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Vma12 PF11712.8 KER25512.1 - 1.2e-22 80.4 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase NDUF_B7 PF05676.13 KER25513.1 - 4.6e-22 77.5 1.6 6.1e-22 77.1 1.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KER25513.1 - 0.0079 16.2 3.2 0.01 15.9 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like LIM PF00412.22 KER25515.1 - 1e-53 179.4 44.4 1.4e-15 57.2 3.0 4.3 4 0 0 4 4 4 4 LIM domain Glyco_transf_64 PF09258.10 KER25519.1 - 4e-88 294.8 0.3 6.2e-88 294.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KER25519.1 - 2.6e-14 53.2 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Exostosin family Cwf_Cwc_15 PF04889.12 KER25520.1 - 2.2e-80 270.0 11.8 2.4e-80 269.8 11.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein VIR_N PF15912.5 KER25520.1 - 0.18 11.3 4.7 0.27 10.8 4.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal NOA36 PF06524.12 KER25520.1 - 0.22 10.8 10.3 0.34 10.2 10.3 1.3 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 KER25520.1 - 0.34 10.6 6.6 0.58 9.8 6.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Myc_N PF01056.18 KER25520.1 - 1.5 8.6 7.1 2.1 8.2 7.1 1.3 1 1 0 1 1 1 0 Myc amino-terminal region PPP4R2 PF09184.11 KER25520.1 - 2.3 7.7 9.7 3 7.4 9.7 1.2 1 0 0 1 1 1 0 PPP4R2 Y_phosphatase PF00102.27 KER25521.1 - 2.6e-84 282.5 0.1 8e-49 166.3 0.2 4.2 3 1 0 3 3 3 3 Protein-tyrosine phosphatase fn3 PF00041.21 KER25521.1 - 1.8e-23 82.7 2.6 5.5e-10 39.5 0.0 4.8 6 0 0 6 6 6 2 Fibronectin type III domain DSPc PF00782.20 KER25521.1 - 5e-08 32.8 0.2 0.00069 19.4 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER25521.1 - 1.8e-05 24.9 0.2 0.089 12.7 0.1 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KER25521.1 - 0.0074 16.4 0.1 0.43 10.7 0.0 2.4 2 0 0 2 2 2 1 Inositol hexakisphosphate ATP-synt PF00231.19 KER25522.1 - 2.1e-75 254.0 0.3 2.4e-75 253.8 0.3 1.0 1 0 0 1 1 1 1 ATP synthase Luteo_coat PF00894.18 KER25522.1 - 0.011 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Luteovirus coat protein DUF5108 PF17133.4 KER25522.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5108) DUF3549 PF12069.8 KER25522.1 - 0.075 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Laminin_G_2 PF02210.24 KER25523.1 - 2.2e-71 238.3 5.2 6.5e-24 84.9 0.1 4.9 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 KER25523.1 - 2.8e-50 169.9 1.2 6e-22 78.3 0.0 5.2 5 2 0 5 5 5 4 Laminin G domain F5_F8_type_C PF00754.25 KER25523.1 - 5.8e-23 81.4 0.1 1.6e-22 80.0 0.1 1.8 1 0 0 1 1 1 1 F5/8 type C domain Amidohydro_1 PF01979.20 KER25523.1 - 3.4e-09 36.5 0.0 8.5e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Laminin_G_3 PF13385.6 KER25523.1 - 1.5e-06 28.5 13.5 0.028 14.6 0.1 4.9 6 0 0 6 6 6 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KER25523.1 - 0.00059 20.1 38.1 0.0024 18.1 7.2 3.9 3 0 0 3 3 3 2 EGF-like domain Amidohydro_3 PF07969.11 KER25523.1 - 0.00061 19.4 0.1 0.091 12.2 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase family GatD_N PF18195.1 KER25523.1 - 0.31 10.4 1.0 0.74 9.2 0.5 1.8 2 0 0 2 2 2 0 GatD N-terminal domain Cadherin PF00028.17 KER25524.1 - 1.5e-35 121.5 2.7 5.6e-05 23.5 0.0 11.3 10 3 0 10 10 10 7 Cadherin domain Cadherin_3 PF16184.5 KER25524.1 - 1.5e-06 28.2 1.5 0.017 15.1 0.0 5.6 5 0 0 5 5 5 1 Cadherin-like Cadherin_2 PF08266.12 KER25524.1 - 0.0052 16.6 0.3 1.6 8.6 0.0 3.8 3 0 0 3 3 3 1 Cadherin-like Josephin PF02099.17 KER25524.1 - 0.19 11.8 0.6 0.41 10.7 0.6 1.5 1 0 0 1 1 1 0 Josephin Myosin_tail_1 PF01576.19 KER25525.1 - 8.5e-52 176.2 172.2 1.1e-51 175.8 172.2 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 KER25525.1 - 9.2e-09 35.3 160.9 0.0021 17.7 44.4 5.7 1 1 4 5 5 5 4 Intermediate filament protein Lebercilin PF15619.6 KER25525.1 - 0.001 18.7 39.3 0.001 18.7 39.3 8.2 1 1 7 8 8 6 2 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 KER25525.1 - 0.0018 18.5 188.2 0.16 12.1 24.5 9.3 1 1 7 8 8 8 3 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KER25525.1 - 0.0026 17.8 95.1 0.052 13.6 6.7 10.4 3 2 6 11 11 11 5 Protein of unknown function (DUF1664) FH2 PF02181.23 KER25525.1 - 0.0028 16.9 7.7 0.0028 16.9 7.7 6.9 1 1 3 7 7 7 1 Formin Homology 2 Domain FAM184 PF15665.5 KER25525.1 - 0.0039 17.0 33.7 0.0039 17.0 33.7 6.9 1 1 5 6 6 4 1 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 KER25525.1 - 0.0044 17.1 4.4 0.0044 17.1 4.4 9.5 2 2 8 10 10 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SKA2 PF16740.5 KER25525.1 - 0.0044 16.8 9.1 0.0044 16.8 9.1 9.1 1 1 9 10 10 9 1 Spindle and kinetochore-associated protein 2 WXG100 PF06013.12 KER25525.1 - 0.026 14.7 1.2 0.026 14.7 1.2 11.3 5 3 5 11 11 11 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 KER25525.1 - 0.11 13.0 0.3 0.11 13.0 0.3 11.7 4 2 6 11 11 11 0 Nucleopolyhedrovirus P10 protein Pallilysin PF18663.1 KER25525.1 - 0.13 12.2 1.5 3.4 7.7 0.2 2.8 2 0 0 2 2 2 0 Pallilysin beta barrel domain DUF3584 PF12128.8 KER25525.1 - 4.8 4.6 160.7 0.074 10.6 51.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Kinesin PF00225.23 KER25526.1 - 1.9e-60 204.6 10.9 7.2e-36 123.8 0.1 4.0 3 1 1 4 4 4 3 Kinesin motor domain Kinesin_assoc PF16183.5 KER25526.1 - 6.6e-06 26.4 21.2 0.0047 17.1 0.1 3.4 2 1 1 3 3 3 2 Kinesin-associated Asp_protease_2 PF13650.6 KER25526.1 - 0.00017 22.1 0.2 0.00063 20.3 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease Microtub_bd PF16796.5 KER25526.1 - 0.0011 18.9 1.2 0.003 17.5 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding DUF1759 PF03564.15 KER25526.1 - 0.0042 17.0 9.6 0.011 15.6 0.0 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF1759) gag-asp_proteas PF13975.6 KER25526.1 - 0.062 13.9 0.1 0.2 12.2 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease GP24_25 PF17388.2 KER25526.1 - 0.6 10.1 8.1 49 3.9 0.1 3.7 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 SNAD4 PF18750.1 KER25528.1 - 0.082 13.0 0.1 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Lipase_GDSL_2 PF13472.6 KER25529.1 - 8.7e-13 49.1 0.0 2.1e-07 31.5 0.0 2.7 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.27 KER25529.1 - 1.6e-10 40.9 0.0 4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_GDSL PF00657.22 KER25529.1 - 0.00065 19.7 0.2 0.004 17.2 0.0 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase GIY-YIG PF01541.24 KER25529.1 - 0.022 15.0 0.1 0.022 15.0 0.1 2.2 3 0 0 3 3 3 0 GIY-YIG catalytic domain Ribosomal_L1 PF00687.21 KER25529.1 - 0.15 11.8 2.8 11 5.7 0.0 3.4 2 2 1 3 3 3 0 Ribosomal protein L1p/L10e family Paz_1 PF18349.1 KER25531.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 PAZ domain UQ_con PF00179.26 KER25532.1 - 1.6e-10 40.7 0.5 3e-10 39.9 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spike_rec_bind PF09408.10 KER25532.1 - 0.11 12.3 0.5 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Spike receptor binding domain DUF5460 PF17544.2 KER25532.1 - 0.74 8.8 1.3 21 3.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5460) Prp19 PF08606.11 KER25533.1 - 8.2e-33 112.2 3.0 8.2e-33 112.2 3.0 1.9 2 0 0 2 2 1 1 Prp19/Pso4-like WD40 PF00400.32 KER25533.1 - 1e-27 95.8 7.9 9.9e-07 29.4 0.0 7.0 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER25533.1 - 1.4e-15 57.4 0.1 0.0034 17.6 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cornichon PF03311.14 KER25533.1 - 7e-10 39.3 0.0 1e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Cornichon protein U-box PF04564.15 KER25533.1 - 4.5e-08 33.1 0.0 9.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KER25533.1 - 1.7e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WD40_like PF17005.5 KER25533.1 - 2.2e-05 23.9 0.0 0.42 9.9 0.1 3.5 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KER25533.1 - 7.4e-05 21.9 0.0 0.12 11.3 0.0 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KER25533.1 - 0.002 18.0 0.0 8.4 6.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cep57_MT_bd PF06657.13 KER25533.1 - 0.0061 17.0 0.6 0.38 11.2 0.0 2.5 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Nbas_N PF15492.6 KER25533.1 - 0.017 14.4 0.1 0.59 9.4 0.1 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KER25533.1 - 0.022 13.4 0.0 0.39 9.3 0.0 2.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 CarboxypepD_reg PF13620.6 KER25533.1 - 0.08 13.2 0.2 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RVT_1 PF00078.27 KER25534.1 - 0.00043 19.9 0.2 0.019 14.5 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.26 KER25535.1 - 1.9e-47 160.4 0.0 2.2e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KER25535.1 - 0.0026 18.0 0.0 0.0053 17.0 0.0 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KER25535.1 - 0.013 15.1 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DinI PF06183.13 KER25535.1 - 0.097 13.0 0.3 16 5.9 0.0 2.5 2 1 0 2 2 2 0 DinI-like family Ank_2 PF12796.7 KER25536.1 - 3.6e-15 56.3 0.2 5.5e-08 33.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER25536.1 - 1.6e-14 54.1 0.3 6.5e-05 23.4 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 KER25536.1 - 2.4e-10 40.1 7.7 3.1e-10 39.7 7.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 KER25536.1 - 1.5e-08 34.7 0.4 0.0064 16.8 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER25536.1 - 7.1e-08 32.1 0.1 0.035 14.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KER25536.1 - 3.6e-05 24.0 0.1 0.14 12.6 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat PKD_channel PF08016.12 KER25536.1 - 0.28 9.8 11.3 0.085 11.5 8.4 1.5 2 0 0 2 2 2 0 Polycystin cation channel cNMP_binding PF00027.29 KER25538.1 - 3.7e-30 103.8 0.4 6.5e-19 67.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 KER25538.1 - 2.7e-23 81.3 0.2 5.5e-23 80.3 0.2 1.6 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 KER25538.1 - 1.3e-22 80.2 18.6 3e-22 79.1 18.6 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER25538.1 - 0.00058 19.8 0.1 0.0018 18.2 0.1 1.9 1 0 0 1 1 1 1 Ion channel Bac_A_amyl_C PF18612.1 KER25538.1 - 0.038 13.7 1.8 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial Alpha amylase C-terminal domain Amidohydro_1 PF01979.20 KER25539.1 - 1.2e-17 64.2 0.0 3.4e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KER25539.1 - 1.5e-05 24.7 0.0 0.00076 19.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family EXOSC1 PF10447.9 KER25540.1 - 5.9e-09 36.5 0.1 2.6e-08 34.4 0.0 2.0 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KER25540.1 - 0.029 14.2 0.0 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region DUF3572 PF12096.8 KER25541.1 - 0.15 12.3 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) Glyco_transf_22 PF03901.17 KER25542.1 - 8.9e-29 100.9 30.4 1.7e-15 57.2 4.1 2.2 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family U-box PF04564.15 KER25543.1 - 4.9e-15 55.5 0.2 1.4e-14 54.0 0.2 1.8 1 0 0 1 1 1 1 U-box domain DUF4218 PF13960.6 KER25544.1 - 0.00084 18.9 0.2 0.0021 17.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4806 PF16064.5 KER25544.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) PTPLA PF04387.14 KER25547.1 - 2.2e-12 47.0 0.3 4e-12 46.2 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 KER25549.1 - 3.1e-07 31.3 0.0 6.9e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 CS domain Peptidase_C48 PF02902.19 KER25550.1 - 1.9e-11 44.2 0.5 1.5e-10 41.3 0.5 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ndr PF03096.14 KER25551.1 - 1.4e-60 204.4 0.0 1.9e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 KER25551.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSP70 PF00012.20 KER25552.1 - 1.5e-270 898.6 10.7 1.7e-270 898.4 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER25552.1 - 3.4e-16 59.0 0.9 1e-13 50.8 0.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KER25552.1 - 1.1e-05 25.8 1.2 0.16 12.4 0.0 3.8 3 2 0 3 3 3 2 Cell division protein FtsA cwf21 PF08312.12 KER25552.1 - 0.016 15.4 1.1 0.82 9.9 0.4 2.5 2 0 0 2 2 2 0 cwf21 domain Phe_tRNA-synt_N PF02912.18 KER25552.1 - 0.038 13.9 1.6 0.13 12.2 1.6 1.9 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain FGGY_C PF02782.16 KER25552.1 - 0.093 12.4 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain YabA PF06156.13 KER25552.1 - 0.42 11.3 3.2 0.96 10.1 2.7 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Spectrin PF00435.21 KER25552.1 - 0.57 10.7 6.1 1.7 9.2 6.1 1.8 1 0 0 1 1 1 0 Spectrin repeat DUF773 PF05600.12 KER25553.1 - 3.8e-65 220.6 4.5 6e-49 167.1 1.6 2.0 2 0 0 2 2 2 2 CDK5 regulatory subunit-associated protein 3 SurA_N_2 PF13623.6 KER25553.1 - 0.087 12.7 1.2 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 SurA N-terminal domain zf-C2H2 PF00096.26 KER25555.1 - 8.8e-17 60.6 23.2 3.1e-06 27.3 3.2 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER25555.1 - 6.7e-14 51.6 26.7 2.6e-06 27.6 0.8 4.9 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER25555.1 - 1.5e-11 44.1 19.4 0.0013 19.4 2.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER25555.1 - 4.2e-08 33.3 3.1 0.061 13.6 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER25555.1 - 5.4e-07 29.5 14.7 0.034 14.1 0.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KER25555.1 - 0.0025 18.1 10.0 3.2 8.3 0.9 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KER25555.1 - 0.067 13.1 11.0 0.56 10.2 0.6 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KER25555.1 - 0.1 12.9 13.6 0.87 9.9 4.9 3.3 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KER25555.1 - 0.65 10.5 4.2 0.36 11.3 0.2 2.7 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 KER25555.1 - 0.72 9.8 3.3 27 4.8 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 LIM PF00412.22 KER25555.1 - 1.2 9.4 3.2 16 5.8 4.1 2.1 1 1 1 2 2 2 0 LIM domain zf_UBZ PF18439.1 KER25555.1 - 1.4 8.6 8.0 9.2 6.0 0.6 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger NRBF2 PF08961.10 KER25556.1 - 0.015 14.9 0.4 0.023 14.3 0.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TPR_2 PF07719.17 KER25556.1 - 0.02 15.0 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Mistic PF11458.8 KER25556.1 - 0.18 11.8 0.3 0.28 11.2 0.3 1.3 1 0 0 1 1 1 0 Membrane-integrating protein Mistic DRMBL PF07522.14 KER25557.1 - 3.2e-19 69.1 0.0 7e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KER25557.1 - 0.0037 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 KER25557.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Actin PF00022.19 KER25558.1 - 1.3e-38 132.7 0.0 1.7e-26 92.8 0.0 3.9 1 1 1 2 2 2 2 Actin RRP36 PF06102.12 KER25559.1 - 2.9e-19 69.7 24.3 3.8e-19 69.3 24.3 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF5410 PF17422.2 KER25559.1 - 0.02 14.2 5.8 0.027 13.8 5.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5410) NUC130_3NT PF08158.12 KER25559.1 - 0.75 10.2 4.9 0.25 11.7 0.7 2.4 3 0 0 3 3 3 0 NUC130/3NT domain DUF1168 PF06658.12 KER25560.1 - 6.5e-37 126.4 5.0 9e-37 125.9 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.10 KER25560.1 - 4 7.5 9.9 5.7 7.0 9.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDE_1 PF03184.19 KER25562.1 - 3.1e-06 27.0 0.0 5.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 KER25562.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KER25562.1 - 0.00015 21.7 0.0 0.054 13.5 0.0 2.7 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain Ank PF00023.30 KER25564.1 - 2.6e-07 30.8 0.5 1.3e-05 25.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KER25564.1 - 3.5e-06 27.5 0.0 9.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER25564.1 - 1.2e-05 25.4 0.3 2.8e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER25564.1 - 3.5e-05 23.9 0.1 0.00067 19.9 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KER25564.1 - 0.00011 22.6 0.0 0.00045 20.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) CDC45 PF02724.14 KER25564.1 - 8.4 4.5 10.3 15 3.7 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop52 PF05997.12 KER25566.1 - 3.7e-34 118.4 1.0 7.2e-34 117.5 1.0 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF410 PF04190.13 KER25566.1 - 0.096 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) P2X_receptor PF00864.19 KER25567.1 - 2.3e-09 36.8 0.0 2.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ATP P2X receptor P2X_receptor PF00864.19 KER25568.1 - 1.2e-97 327.3 0.5 1.3e-97 327.1 0.5 1.0 1 0 0 1 1 1 1 ATP P2X receptor BrkDBD PF09607.10 KER25568.1 - 0.015 15.1 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain WAP PF00095.21 KER25568.1 - 0.42 11.0 0.2 0.42 11.0 0.2 2.4 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Retrotrans_gag PF03732.17 KER25570.1 - 0.083 13.2 0.0 0.19 12.0 0.0 1.6 1 1 1 2 2 2 0 Retrotransposon gag protein GDA1_CD39 PF01150.17 KER25572.1 - 2.9e-79 266.7 0.0 6.2e-79 265.6 0.0 1.4 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BTP PF05232.12 KER25572.1 - 0.56 10.3 2.5 1.1 9.3 2.5 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter dCMP_cyt_deam_1 PF00383.23 KER25573.1 - 2.8e-17 62.5 0.4 5.2e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KER25573.1 - 7.8e-15 54.8 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase NAD1 PF18778.1 KER25573.1 - 0.03 14.4 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 KER25573.1 - 0.039 14.1 0.2 0.086 13.0 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KER25573.1 - 0.048 13.7 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 APOBEC2 Bd3614-deam PF14439.6 KER25573.1 - 0.075 13.1 3.9 0.37 10.9 0.5 2.8 2 1 0 2 2 2 0 Bd3614-like deaminase APOBEC3 PF18771.1 KER25573.1 - 0.19 11.9 0.2 0.36 11.0 0.2 1.4 1 0 0 1 1 1 0 APOBEC3 zf-C2H2_aberr PF17017.5 KER25574.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger PDEase_I PF00233.19 KER25575.1 - 3.5e-68 229.9 1.0 5.3e-68 229.3 1.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PCP_red PF08369.10 KER25576.1 - 0.03 14.5 4.8 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit NT-C2 PF10358.9 KER25576.1 - 0.11 12.3 0.3 3.7 7.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins NAP PF00956.18 KER25578.1 - 6.1e-61 206.0 0.0 4.2e-51 173.7 0.0 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Strabismus PF06638.11 KER25579.1 - 1.7e-21 76.5 4.5 2.3e-14 53.0 0.0 4.0 4 1 0 4 4 4 3 Strabismus protein BTB PF00651.31 KER25580.1 - 9e-14 51.7 0.3 5.9e-05 23.3 0.0 3.7 3 1 1 4 4 4 2 BTB/POZ domain BACK PF07707.15 KER25580.1 - 2.4e-07 30.8 2.6 5e-07 29.8 0.5 2.7 2 1 0 2 2 2 1 BTB And C-terminal Kelch BORCS7 PF16088.5 KER25581.1 - 0.017 15.4 0.2 0.081 13.2 0.2 2.1 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 N-glycanase_N PF09112.10 KER25581.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Hydrolase_6 PF13344.6 KER25583.1 - 5.9e-16 58.4 0.0 9.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DNA_methylase PF00145.17 KER25587.1 - 1.4e-37 129.8 0.0 4.2e-37 128.2 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Sulfotransfer_1 PF00685.27 KER25589.1 - 4e-55 187.2 0.0 5.9e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER25589.1 - 9.4e-12 45.8 0.0 3.2e-09 37.5 0.0 2.3 1 1 0 2 2 2 2 Sulfotransferase family Reprolysin PF01421.19 KER25590.1 - 4.9e-33 114.7 0.8 7.8e-33 114.1 0.1 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.23 KER25590.1 - 1e-19 71.1 20.3 1e-19 71.1 20.3 4.1 6 0 0 6 6 3 1 Disintegrin ADAM_CR PF08516.12 KER25590.1 - 3.2e-13 50.1 0.6 3.2e-13 50.1 0.6 3.4 3 0 0 3 3 3 1 ADAM cysteine-rich Reprolysin_5 PF13688.6 KER25590.1 - 8e-13 49.0 0.1 2e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KER25590.1 - 3e-11 43.9 0.0 6.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KER25590.1 - 7.4e-05 22.5 0.8 0.00026 20.7 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KER25590.1 - 0.00046 20.1 0.4 0.0013 18.6 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.13 KER25590.1 - 0.0028 18.0 9.3 0.0028 18.0 9.3 5.6 5 0 0 5 5 3 1 EGF-like domain Peptidase_M57 PF12388.8 KER25590.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 KER25590.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 KER25590.1 - 0.19 11.7 0.1 0.44 10.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M54 Rad51 PF08423.11 KER25592.1 - 7.7e-29 100.7 0.0 2.2e-22 79.6 0.0 2.2 2 0 0 2 2 2 2 Rad51 RhoGEF PF00621.20 KER25592.1 - 4.8e-13 49.7 0.3 3.5e-10 40.4 0.1 2.9 3 1 0 3 3 3 2 RhoGEF domain AAA_25 PF13481.6 KER25592.1 - 4.1e-06 26.5 0.0 8.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER25592.1 - 7.9e-06 25.4 0.3 2.4e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 KaiC RecA PF00154.21 KER25592.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein adh_short PF00106.25 KER25593.1 - 1.4e-45 155.2 1.2 2e-45 154.7 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER25593.1 - 2.2e-40 138.7 0.2 2.8e-39 135.1 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER25593.1 - 6.7e-07 29.4 3.5 5.6e-06 26.4 3.5 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KER25593.1 - 0.00017 21.1 0.2 0.00052 19.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SET PF00856.28 KER25594.1 - 4e-06 27.3 0.4 2.6e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KER25594.1 - 4.7e-06 27.3 0.0 2.5e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding Mog1 PF04603.12 KER25595.1 - 2.8e-30 105.5 0.7 8.9e-29 100.6 0.2 2.2 2 0 0 2 2 2 2 Ran-interacting Mog1 protein Nckap1 PF09735.9 KER25596.1 - 1.4e-293 977.0 1.1 7.4e-186 620.3 0.0 3.6 3 1 0 3 3 3 3 Membrane-associated apoptosis protein CH PF00307.31 KER25597.1 - 6.1e-42 142.2 0.2 1.5e-20 73.4 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Plectin PF00681.20 KER25597.1 - 2.3e-32 110.6 0.1 0.058 13.3 0.0 17.4 18 1 1 19 19 19 7 Plectin repeat CAMSAP_CH PF11971.8 KER25597.1 - 7.7e-10 38.5 0.0 1.5e-06 27.9 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 KER25597.1 - 0.00014 22.3 33.1 0.0014 19.1 0.7 7.3 7 0 0 7 7 7 2 Spectrin repeat ING PF12998.7 KER25597.1 - 0.069 13.7 0.0 0.49 11.0 0.0 2.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Ion_trans PF00520.31 KER25598.1 - 9.4e-31 106.9 8.7 1.3e-30 106.4 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER25598.1 - 5.5e-11 42.3 0.5 5.5e-11 42.3 0.5 2.2 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KER25598.1 - 3.3e-10 39.9 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 KER25598.1 - 6e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KER25598.1 - 0.0024 17.8 0.0 0.0069 16.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KER25598.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 PAS fold EloA-BP1 PF15870.5 KER25599.1 - 5e-47 160.2 0.1 8.8e-47 159.4 0.1 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 RNase_T PF00929.24 KER25599.1 - 0.017 15.7 0.1 0.068 13.7 0.1 2.0 1 1 0 1 1 1 0 Exonuclease COX5B PF01215.19 KER25600.1 - 0.00035 20.3 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb FHA PF00498.26 KER25603.1 - 3e-13 49.9 0.0 7.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain SAC3_GANP PF03399.16 KER25604.1 - 0.078 12.4 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 SAC3/GANP family Lenti_VIF_2 PF07401.12 KER25605.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Bovine Lentivirus VIF protein PSD4 PF07631.11 KER25605.1 - 0.039 14.5 0.0 0.065 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Pom PF17251.2 KER25606.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protochlamydia outer membrane protein DUF389 PF04087.14 KER25608.1 - 0.00037 20.6 2.2 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF389) DUF294_C PF10335.9 KER25609.1 - 0.00029 20.6 0.8 0.015 15.1 0.1 2.4 2 1 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain Exo_endo_phos PF03372.23 KER25610.1 - 1.4e-10 41.1 0.0 5.9e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HLH PF00010.26 KER25611.1 - 4.9e-13 48.8 1.2 1.2e-12 47.6 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2205 PF10224.9 KER25611.1 - 0.019 15.0 0.3 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 Short coiled-coil protein HALZ PF02183.18 KER25611.1 - 0.11 12.7 0.2 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 KER25611.1 - 0.2 11.4 0.2 0.45 10.3 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.6 KER25611.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein TPR_10 PF13374.6 KER25611.1 - 1.1 9.2 2.8 28 4.7 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 KER25611.1 - 1.1 7.4 7.5 1.7 6.8 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SUA5 PF03481.13 KER25613.1 - 0.0099 16.4 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PulG PF11773.8 KER25613.1 - 0.17 11.7 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin PAN_1 PF00024.26 KER25614.1 - 0.00014 21.8 1.2 0.00027 20.8 1.2 1.5 1 0 0 1 1 1 1 PAN domain DUF3522 PF12036.8 KER25615.1 - 1.5e-30 106.9 10.4 1.5e-18 67.8 5.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3522) DUF2894 PF11445.8 KER25615.1 - 0.19 12.2 3.6 0.21 12.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF2628 PF10947.8 KER25615.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Parvo_NS1 PF01057.17 KER25617.1 - 9.2e-16 57.7 0.3 1.2e-15 57.4 0.3 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 KER25617.1 - 1.1e-12 47.6 0.2 1.1e-12 47.6 0.2 1.0 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.6 KER25617.1 - 0.02 14.9 0.2 0.058 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KER25617.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF1778 PF08681.11 KER25617.1 - 0.045 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) AAA_7 PF12775.7 KER25617.1 - 0.084 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KER25617.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3512 PF12024.8 KER25617.1 - 0.16 11.4 0.3 0.24 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) AAA PF00004.29 KER25617.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KER25618.1 - 0.0012 18.0 1.2 0.0073 15.4 0.3 2.4 2 1 1 3 3 3 1 Parvovirus non-structural protein NS1 ATP-synt_C PF00137.21 KER25619.1 - 9.8e-22 77.1 24.8 2.1e-12 47.2 12.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 KER25619.1 - 0.1 13.0 0.2 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 SLATT_5 PF18160.1 KER25619.1 - 0.44 9.9 0.1 0.44 9.9 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 SLC35F PF06027.12 KER25619.1 - 0.93 8.9 6.5 0.56 9.7 1.9 2.0 1 1 1 2 2 2 0 Solute carrier family 35 IQ PF00612.27 KER25620.1 - 1.1e-07 31.0 18.9 2.5e-05 23.7 0.7 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif RasGAP PF00616.19 KER25620.1 - 6.1e-06 26.1 1.0 4.8e-05 23.1 0.0 2.8 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KER25620.1 - 2.3e-05 24.6 0.0 7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 RasGAP C-terminus XendoU PF09412.10 KER25623.1 - 1.2e-74 250.9 0.0 1.4e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 KER25623.1 - 0.0074 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease zf-C2H2 PF00096.26 KER25624.1 - 1.3e-13 50.6 31.0 0.00097 19.5 1.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER25624.1 - 1.4e-11 44.2 25.1 0.011 16.5 1.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER25624.1 - 2.3e-10 40.4 28.6 5.7e-07 29.7 3.0 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER25624.1 - 0.00082 19.6 10.4 0.39 11.1 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KER25624.1 - 0.077 13.1 11.0 0.45 10.7 2.4 3.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.7 KER25624.1 - 0.33 11.4 7.7 14 6.2 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 KER25624.1 - 0.33 11.4 6.6 29 5.3 0.1 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_9 PF14369.6 KER25624.1 - 0.74 10.1 13.3 3.7 7.9 0.0 4.3 4 0 0 4 4 4 0 zinc-ribbon Robl_LC7 PF03259.17 KER25625.1 - 7.8e-17 60.8 0.0 9.3e-17 60.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Bestrophin PF01062.21 KER25626.1 - 1.6e-65 221.5 9.2 5.2e-36 124.5 1.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 KER25627.1 - 2.6e-67 227.3 7.5 1.1e-34 120.2 1.6 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2280 PF10045.9 KER25628.1 - 0.053 13.8 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Thioredoxin PF00085.20 KER25630.1 - 7e-59 196.2 0.2 1.2e-28 99.1 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KER25630.1 - 5.7e-39 133.9 0.3 1.9e-29 102.9 0.2 3.8 2 2 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KER25630.1 - 5.8e-09 35.5 2.4 1.1e-08 34.5 2.4 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 KER25630.1 - 3.9e-07 30.2 0.1 0.023 14.9 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KER25630.1 - 3.3e-06 27.5 0.3 0.0069 16.8 0.0 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KER25630.1 - 6e-06 26.2 0.2 0.0081 16.1 0.0 3.0 2 1 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 KER25630.1 - 0.0003 20.3 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KER25630.1 - 0.00032 21.0 0.1 0.91 9.9 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KER25630.1 - 0.002 17.9 0.4 7.8 6.2 0.0 3.5 4 0 0 4 4 4 2 Redoxin ERp29_N PF07912.13 KER25630.1 - 0.0035 17.5 0.7 7.6 6.7 0.1 3.9 4 1 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 KER25630.1 - 0.12 12.2 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 KER25630.1 - 0.13 12.5 0.5 20 5.5 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin Transglut_N PF00868.20 KER25631.1 - 0.023 15.1 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family C1q PF00386.21 KER25633.1 - 0.023 14.9 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 C1q domain RVT_1 PF00078.27 KER25635.1 - 4.5e-07 29.6 0.0 5.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER25638.1 - 8e-43 146.7 0.0 4.4e-39 134.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER25638.1 - 8.1e-31 107.2 0.0 5.4e-25 88.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER25638.1 - 6.5e-05 22.4 0.0 0.00014 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER25638.1 - 7.4e-05 21.7 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KER25638.1 - 0.028 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER25638.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain BTB PF00651.31 KER25639.1 - 2.2e-19 69.7 0.2 1.4e-17 63.9 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain HK PF02110.15 KER25641.1 - 0.17 11.2 0.0 1.2 8.4 0.0 1.9 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Acatn PF13000.7 KER25645.1 - 5.4e-112 375.1 7.2 1.2e-74 251.8 1.5 3.2 2 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Vps54 PF07928.12 KER25648.1 - 1.7e-37 128.8 0.3 7.6e-37 126.8 0.0 2.3 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KER25648.1 - 4.8e-10 39.2 5.1 3e-09 36.6 3.9 2.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 KER25648.1 - 0.00028 20.8 1.0 0.00087 19.2 1.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Integrin_beta PF00362.18 KER25652.1 - 1.5e-87 293.4 0.0 2e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Integrin beta chain VWA domain PSI_integrin PF17205.3 KER25652.1 - 1.5e-08 34.2 4.0 1.5e-08 34.2 4.0 2.6 3 0 0 3 3 3 1 Integrin plexin domain I-EGF_1 PF18372.1 KER25652.1 - 2.4e-05 24.3 4.8 2.4e-05 24.3 4.8 2.6 2 0 0 2 2 2 1 Integrin beta epidermal growth factor like domain 1 Secapin PF17521.2 KER25652.1 - 0.16 11.8 0.6 16 5.4 0.1 2.8 2 0 0 2 2 2 0 Honey bee peptides Integrin_b_cyt PF08725.11 KER25653.1 - 6.3e-19 67.4 0.2 1.1e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.13 KER25653.1 - 1.2e-06 28.7 42.4 0.00018 21.8 10.2 3.4 3 0 0 3 3 3 2 EGF-like domain STOP PF05217.12 KER25653.1 - 0.038 14.3 6.2 0.038 14.3 6.2 3.8 4 0 0 4 4 4 0 STOP protein I-EGF_1 PF18372.1 KER25653.1 - 6.9 6.9 31.9 0.055 13.6 6.6 3.7 3 1 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 RVT_1 PF00078.27 KER25655.1 - 0.0095 15.5 1.3 0.48 9.9 0.2 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Sad1_UNC PF07738.13 KER25656.1 - 5.8e-28 97.5 0.2 1.3e-27 96.4 0.1 1.7 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal CAP PF00188.26 KER25659.1 - 5.3e-43 146.8 0.1 1.3e-20 74.5 0.0 2.6 2 0 0 2 2 2 2 Cysteine-rich secretory protein family DEAD PF00270.29 KER25660.1 - 1.6e-40 138.8 0.1 2.7e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER25660.1 - 1.5e-26 92.9 0.9 4.5e-24 84.9 0.2 2.8 2 1 1 3 3 3 2 Helicase conserved C-terminal domain CMS1 PF14617.6 KER25660.1 - 4.8e-09 35.9 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KER25660.1 - 1.1e-08 35.3 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KER25660.1 - 0.00043 19.9 0.0 0.00073 19.1 0.0 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KER25660.1 - 0.0094 16.3 0.1 0.025 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER25660.1 - 0.25 11.6 1.3 1.1 9.6 0.6 2.5 1 1 1 2 2 2 0 AAA domain Acyl_transf_3 PF01757.22 KER25662.1 - 1e-23 84.0 41.2 1e-23 84.0 41.2 1.9 2 0 0 2 2 2 1 Acyltransferase family 7TM_GPCR_Srt PF10321.9 KER25663.1 - 0.013 14.5 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF2685 PF10886.8 KER25664.1 - 0.14 12.4 0.4 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) MPC PF03650.13 KER25665.1 - 7.9e-16 58.2 0.2 1.7e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Pro_isomerase PF00160.21 KER25666.1 - 1.9e-36 125.7 0.0 3.6e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-LITAF-like PF10601.9 KER25667.1 - 2.5e-13 50.1 7.2 4.3e-13 49.3 7.2 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Atrophin-1 PF03154.15 KER25667.1 - 0.36 9.1 5.0 0.45 8.7 5.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family GRIP PF01465.20 KER25668.1 - 1.8e-11 43.7 0.3 4.8e-11 42.4 0.3 1.8 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 KER25668.1 - 8.2e-10 38.6 1.6 8.2e-10 38.6 1.6 5.0 4 0 0 4 4 4 1 Rab binding domain LemA PF04011.12 KER25668.1 - 2.6 7.9 8.6 0.45 10.3 1.5 3.3 2 1 1 3 3 3 0 LemA family ArfGap PF01412.18 KER25669.1 - 1.7e-40 137.7 0.1 2.8e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RC-P840_PscD PF10657.9 KER25669.1 - 0.014 15.5 0.0 0.12 12.5 0.0 2.2 1 1 1 2 2 2 0 Photosystem P840 reaction centre protein PscD LTD PF00932.19 KER25671.1 - 3e-10 40.4 0.0 4.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Lamin Tail Domain Cupin_8 PF13621.6 KER25672.1 - 1.2e-34 120.2 0.0 1.8e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KER25672.1 - 0.00046 20.6 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KER25672.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KER25672.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain PDEase_I PF00233.19 KER25673.1 - 2.5e-70 236.9 0.5 3.5e-70 236.4 0.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TRIC PF05197.13 KER25676.1 - 2e-75 252.6 2.0 2.7e-75 252.2 2.0 1.2 1 0 0 1 1 1 1 TRIC channel TED_complement PF07678.14 KER25677.1 - 4.8e-26 91.5 0.0 9e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KER25677.1 - 1.3e-17 64.2 0.3 3.7e-17 62.8 0.3 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M_BRD PF07703.14 KER25677.1 - 2.1e-15 57.3 1.0 5.7e-15 55.9 0.4 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 KER25677.1 - 3e-08 34.0 0.0 2.2e-06 28.0 0.0 3.0 3 0 0 3 3 3 1 MG2 domain A2M PF00207.22 KER25677.1 - 1.8e-07 30.9 0.2 6.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG3 PF17791.1 KER25677.1 - 3e-05 24.2 0.0 0.00022 21.5 0.0 2.5 2 0 0 2 2 2 1 Macroglobulin domain MG3 Ldl_recept_a PF00057.18 KER25677.1 - 0.078 13.2 3.7 0.17 12.1 3.7 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Spore-coat_CotD PF11122.8 KER25677.1 - 0.14 13.0 0.5 0.43 11.4 0.5 1.8 1 0 0 1 1 1 0 Inner spore coat protein D MFS_1 PF07690.16 KER25679.1 - 4e-18 65.4 34.9 1e-11 44.4 10.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KER25681.1 - 3.7e-24 84.5 13.6 3.3e-06 27.7 0.1 8.1 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER25681.1 - 7.9e-07 29.3 0.0 0.18 12.1 0.0 4.7 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 KER25681.1 - 0.11 13.1 0.2 0.11 13.1 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PAP_assoc PF03828.19 KER25682.1 - 9.9e-14 51.3 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KER25682.1 - 1.7e-13 50.7 0.0 3.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KER25682.1 - 0.0084 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RNA_pol_Rbc25 PF08292.12 KER25684.1 - 1.5e-25 89.9 0.1 2.4e-23 82.8 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KER25684.1 - 1.9e-14 53.7 0.1 3.9e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KER25684.1 - 0.0019 18.5 0.0 0.0044 17.3 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain LRR_6 PF13516.6 KER25685.1 - 0.0012 18.8 7.8 0.15 12.2 0.2 4.7 4 0 0 4 4 4 2 Leucine Rich repeat F-box-like PF12937.7 KER25685.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KER25685.1 - 0.003 17.9 12.0 0.033 14.6 0.6 4.6 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KER25685.1 - 0.015 15.2 1.0 0.1 12.5 0.1 2.6 2 0 0 2 2 2 0 F-box domain DUF4276 PF14103.6 KER25685.1 - 0.088 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) LRR_8 PF13855.6 KER25685.1 - 0.41 10.5 2.9 1.6 8.5 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat AAA_6 PF12774.7 KER25686.1 - 3e-140 466.8 0.0 1.3e-138 461.5 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KER25686.1 - 4.2e-129 431.8 5.0 4.2e-129 431.8 5.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KER25686.1 - 4.2e-125 418.0 5.3 4.2e-125 418.0 5.3 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KER25686.1 - 4e-92 308.2 0.0 9.5e-92 307.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER25686.1 - 7e-81 271.8 0.1 8.4e-78 261.7 0.0 3.3 2 1 1 3 3 3 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER25686.1 - 4.1e-75 251.7 3.8 5.5e-75 251.3 0.3 3.2 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER25686.1 - 1.8e-71 239.4 0.1 1.9e-66 223.0 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER25686.1 - 5.9e-52 175.8 0.1 1.5e-51 174.4 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER25686.1 - 1.6e-42 145.8 6.5 3.3e-42 144.8 6.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER25686.1 - 1.4e-34 118.7 0.1 1.1e-32 112.6 0.1 3.7 1 1 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KER25686.1 - 1.1e-23 83.8 0.0 1.5e-07 31.5 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KER25686.1 - 1.5e-20 73.6 0.1 4.8e-20 71.9 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KER25686.1 - 1.2e-15 57.5 0.3 1e-14 54.6 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KER25686.1 - 7.7e-07 29.5 0.9 0.051 13.8 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 KER25686.1 - 1.3e-05 25.7 0.1 0.71 10.2 0.0 4.9 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 KER25686.1 - 3e-05 24.4 0.1 2.1 8.8 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KER25686.1 - 0.011 16.0 0.0 1.1 9.5 0.0 3.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KER25686.1 - 0.03 14.1 0.3 7.7 6.4 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER25686.1 - 0.054 13.4 0.9 5.1 7.0 0.0 3.7 4 0 0 4 4 3 0 RsgA GTPase PCI PF01399.27 KER25686.1 - 0.083 13.4 11.5 2.1 8.9 0.0 4.8 5 0 0 5 5 3 0 PCI domain ABC_tran PF00005.27 KER25686.1 - 0.13 12.8 0.2 7.6 7.1 0.0 3.5 3 0 0 3 3 2 0 ABC transporter HlyE PF06109.13 KER25686.1 - 0.16 11.2 7.9 1.9 7.8 0.5 3.0 3 0 0 3 3 3 0 Haemolysin E (HlyE) AAA_19 PF13245.6 KER25686.1 - 0.19 12.1 2.9 8.4 6.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain PSK_trans_fac PF07704.11 KER25686.1 - 2.9 8.7 7.2 0.82 10.5 0.2 3.3 2 0 0 2 2 2 0 Rv0623-like transcription factor Flagellin_C PF00700.21 KER25686.1 - 6 7.3 6.1 1.6 9.1 1.8 2.4 2 0 0 2 2 1 0 Bacterial flagellin C-terminal helical region zf-H2C2_2 PF13465.6 KER25687.1 - 2.8e-12 46.4 27.8 5.7e-09 36.0 1.1 5.6 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER25687.1 - 0.0005 20.4 15.4 0.0035 17.7 2.4 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KER25687.1 - 0.012 15.3 2.4 0.012 15.3 2.4 4.0 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KER25687.1 - 0.013 16.2 13.8 0.033 15.0 1.2 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KER25687.1 - 0.06 14.0 18.3 0.91 10.2 0.6 4.2 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KER25687.1 - 3.9 7.7 30.3 0.16 12.1 2.9 5.0 4 0 0 4 4 4 0 Zinc ribbon domain ArfGap PF01412.18 KER25688.1 - 3.9e-35 120.5 0.0 5.8e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 KER25688.1 - 0.15 12.0 1.6 12 6.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger AAA_6 PF12774.7 KER25690.1 - 1.5e-129 431.6 0.0 3.3e-89 299.1 0.0 3.4 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER25690.1 - 6.3e-114 381.2 6.7 4.8e-64 216.9 5.4 4.7 4 1 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KER25690.1 - 1e-96 323.8 3.0 1.7e-96 323.1 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KER25690.1 - 3.2e-92 308.6 0.0 8e-92 307.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER25690.1 - 1.7e-86 288.9 0.6 3.7e-85 284.5 0.8 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region DHC_N1 PF08385.12 KER25690.1 - 5.9e-83 279.4 20.1 1.8e-77 261.3 1.3 5.1 6 1 0 6 6 6 2 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 KER25690.1 - 1e-68 230.4 4.5 1.1e-64 217.3 0.2 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER25690.1 - 3.5e-55 186.3 0.0 1e-54 184.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER25690.1 - 1.3e-40 138.2 0.0 1.5e-39 134.8 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KER25690.1 - 5.1e-33 114.5 13.1 6.7e-13 48.4 0.2 3.4 3 0 0 3 3 3 3 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KER25690.1 - 2.5e-25 89.1 0.0 1.7e-07 31.3 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER25690.1 - 1.1e-20 73.7 0.0 1.3e-19 70.2 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KER25690.1 - 3.9e-17 62.5 0.0 1.9e-16 60.3 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KER25690.1 - 4.8e-07 30.3 0.2 0.23 11.9 0.0 4.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER25690.1 - 2.1e-05 24.8 0.4 4.8 7.5 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KER25690.1 - 0.0005 20.5 0.0 29 5.0 0.0 4.9 4 0 0 4 4 4 0 AAA ATPase domain MARVEL PF01284.23 KER25690.1 - 0.0011 19.0 3.6 0.0022 18.1 3.6 1.5 1 0 0 1 1 1 1 Membrane-associating domain Sigma54_activat PF00158.26 KER25690.1 - 0.013 15.2 0.1 1.3 8.7 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain DNA_photolyase PF00875.18 KER25690.1 - 0.14 12.1 0.3 9.4 6.2 0.5 3.0 2 0 0 2 2 2 0 DNA photolyase ABC_tran PF00005.27 KER25690.1 - 0.39 11.2 1.5 20 5.7 0.0 4.0 4 0 0 4 4 3 0 ABC transporter AAA_19 PF13245.6 KER25690.1 - 3 8.2 14.6 7.6 6.9 0.0 5.4 5 0 0 5 5 5 0 AAA domain DUF1515 PF07439.11 KER25690.1 - 8 6.5 8.7 1.1 9.3 1.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) PLAC8 PF04749.17 KER25691.1 - 1.1e-10 42.4 9.9 1.5e-10 41.9 9.9 1.2 1 0 0 1 1 1 1 PLAC8 family LEP503 PF15221.6 KER25691.1 - 0.64 10.4 8.7 0.59 10.5 0.4 2.2 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 gag-asp_proteas PF13975.6 KER25692.1 - 0.0049 17.4 0.0 0.53 10.9 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER25692.1 - 0.042 14.5 0.0 0.14 12.8 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 KER25692.1 - 0.089 12.6 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 KER25693.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YL1 PF05764.13 KER25694.1 - 2.2e-17 64.0 20.0 2.7e-17 63.7 20.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KER25694.1 - 1.8e-13 50.0 0.2 4.3e-13 48.8 0.2 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain YL1 PF05764.13 KER25695.1 - 1.2e-39 136.9 23.7 1.5e-39 136.6 23.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KER25695.1 - 3.2e-13 49.2 0.2 7.1e-13 48.1 0.2 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF5537 PF17690.1 KER25696.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5537) Tom6 PF17112.5 KER25696.1 - 0.45 10.0 1.8 24 4.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal LIM PF00412.22 KER25697.1 - 5.8e-12 45.7 1.9 6.8e-12 45.4 1.9 1.1 1 0 0 1 1 1 1 LIM domain zf_UBZ PF18439.1 KER25697.1 - 9.5 5.9 9.4 0.47 10.1 2.5 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 KER25698.1 - 3e-15 56.2 5.8 3.3e-15 56.1 5.8 1.0 1 0 0 1 1 1 1 LIM domain YacG PF03884.14 KER25698.1 - 0.0015 18.2 5.5 0.4 10.4 1.5 2.2 2 0 0 2 2 2 2 DNA gyrase inhibitor YacG zf-ACC PF17848.1 KER25698.1 - 0.011 15.8 4.6 0.45 10.6 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 KER25698.1 - 0.069 12.8 2.6 0.069 12.8 2.6 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Mut7-C PF01927.16 KER25698.1 - 0.11 12.6 2.4 0.18 11.9 2.4 1.4 1 1 0 1 1 1 0 Mut7-C RNAse domain RabGAP-TBC PF00566.18 KER25699.1 - 6.1e-48 163.3 0.0 8.7e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.19 KER25699.1 - 7.9e-12 45.3 0.0 2.2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.28 KER25699.1 - 1.6e-11 43.6 0.1 3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KER25699.1 - 7.2e-11 41.6 0.0 1.9e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KER25699.1 - 1.8e-10 40.5 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ComZ PF10815.8 KER25699.1 - 0.0038 17.2 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 ComZ Na_sulph_symp PF00939.19 KER25703.1 - 0.041 12.9 0.1 0.053 12.6 0.1 1.1 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region Na_sulph_symp PF00939.19 KER25704.1 - 5.9e-20 71.8 0.4 6.7e-20 71.6 0.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KER25704.1 - 4.9e-12 45.7 1.0 5e-12 45.6 1.0 1.0 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 KER25705.1 - 1.7e-56 192.2 0.0 4.9e-56 190.7 0.0 1.6 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KER25705.1 - 1.1e-19 70.8 13.8 1.4e-17 63.8 1.7 2.0 1 1 1 2 2 2 2 Citrate transporter EF-hand_1 PF00036.32 KER25707.1 - 5.6e-13 47.4 2.3 1.8e-06 27.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER25707.1 - 2.1e-11 44.1 3.0 2.4e-11 43.9 3.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER25707.1 - 2.1e-10 39.6 3.9 9.9e-05 22.0 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KER25707.1 - 1.2e-08 34.0 3.1 0.00023 20.5 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER25707.1 - 1e-05 25.3 2.8 9e-05 22.2 1.7 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER25707.1 - 0.00054 20.3 1.3 0.00077 19.8 1.3 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER25707.1 - 0.00076 19.4 0.6 0.00089 19.2 0.6 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.11 KER25707.1 - 0.058 13.9 0.4 0.071 13.6 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 KER25708.1 - 1.6e-14 52.3 0.5 3e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER25708.1 - 2.8e-14 51.9 0.2 1.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER25708.1 - 5.9e-13 48.4 2.5 2.3e-08 33.8 0.7 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER25708.1 - 1.1e-11 43.7 0.7 7.4e-05 22.4 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KER25708.1 - 3.4e-11 43.4 0.2 3.9e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER25708.1 - 0.0003 21.1 0.8 0.00039 20.7 0.8 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER25708.1 - 0.0011 18.9 0.2 0.0014 18.5 0.2 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KER25708.1 - 0.0072 16.2 0.5 0.014 15.3 0.3 1.6 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.6 KER25708.1 - 0.027 14.9 0.5 1.4 9.4 0.0 2.0 1 1 1 2 2 2 0 Toprim-like DUF5109 PF17134.4 KER25708.1 - 0.067 13.1 0.1 0.52 10.2 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5109) Dockerin_1 PF00404.18 KER25708.1 - 0.08 13.1 0.0 14 6.0 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain SSURE PF11966.8 KER25708.1 - 0.084 12.6 0.1 0.51 10.1 0.1 1.9 1 1 1 2 2 2 0 Fibronectin-binding repeat EF-hand_like PF09279.11 KER25708.1 - 0.12 12.9 0.1 7.5 7.1 0.0 2.0 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 KER25712.1 - 8.7e-23 78.1 5.0 2.4e-05 23.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER25712.1 - 1.1e-22 80.3 5.5 1.9e-12 47.5 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER25712.1 - 1.2e-18 65.4 4.3 4e-05 23.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER25712.1 - 1.9e-17 61.9 4.3 0.00015 21.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KER25712.1 - 1.4e-16 60.1 4.6 4.5e-06 26.4 0.8 4.0 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER25712.1 - 3.3e-06 27.4 0.8 0.0026 18.1 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER25712.1 - 0.00017 21.5 2.1 0.95 9.4 0.0 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KER25712.1 - 0.00018 21.3 2.1 0.02 14.7 0.1 3.0 3 0 0 3 3 3 1 EF hand DUF5580 PF17743.1 KER25712.1 - 0.00083 18.0 0.2 0.001 17.7 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_9 PF14658.6 KER25712.1 - 0.01 16.1 0.1 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 KER25712.1 - 0.024 14.6 0.5 15 5.5 0.0 3.1 1 1 2 3 3 3 0 Caleosin related protein p25-alpha PF05517.12 KER25712.1 - 0.083 13.1 1.9 0.42 10.8 0.7 2.2 1 1 1 2 2 2 0 p25-alpha RST PF12174.8 KER25712.1 - 0.13 12.2 0.1 1.2 9.1 0.0 2.4 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain DUF1456 PF07308.13 KER25712.1 - 0.41 11.0 2.9 6.5 7.2 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 KER25713.1 - 3e-24 82.7 10.0 1.7e-07 30.3 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER25713.1 - 8.4e-23 80.6 9.8 4.4e-13 49.5 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER25713.1 - 3.7e-20 70.1 10.1 2.7e-05 23.7 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER25713.1 - 5.7e-19 66.7 8.1 5.1e-06 25.7 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KER25713.1 - 5e-14 51.9 5.4 5.9e-06 26.0 0.3 3.3 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER25713.1 - 5.2e-06 26.8 6.7 0.00081 19.7 0.5 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER25713.1 - 1.9e-05 24.4 6.3 0.052 13.4 0.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KER25713.1 - 2.4e-05 24.2 3.6 0.47 10.4 0.2 3.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KER25713.1 - 0.0062 16.5 2.5 4.3 7.2 0.0 3.3 2 1 2 4 4 4 2 Caleosin related protein DUF1456 PF07308.13 KER25713.1 - 0.013 15.8 4.0 0.19 12.1 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) EF-hand_11 PF08976.11 KER25713.1 - 0.043 14.7 0.7 11 7.0 0.2 2.9 1 1 1 3 3 3 0 EF-hand domain p25-alpha PF05517.12 KER25713.1 - 0.048 13.8 1.0 0.048 13.8 1.0 2.6 1 1 1 2 2 2 0 p25-alpha Sars6 PF12133.8 KER25713.1 - 0.13 12.2 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus SHOCT PF09851.9 KER25713.1 - 0.17 11.6 1.5 0.57 10.0 0.1 2.6 2 0 0 2 2 2 0 Short C-terminal domain EF-hand_5 PF13202.6 KER25714.1 - 8.4e-06 25.1 0.1 1.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KER25714.1 - 2.3e-05 24.7 0.0 4.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER25714.1 - 3.4e-05 23.1 0.1 8e-05 21.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER25714.1 - 0.00013 21.7 0.1 0.00034 20.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KER25714.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 KER25715.1 - 7.4e-17 59.6 0.0 6.5e-05 22.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER25715.1 - 3.2e-15 54.7 0.4 0.00017 21.2 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KER25715.1 - 1.4e-14 54.3 0.5 2.1e-06 28.1 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER25715.1 - 1.9e-10 39.7 0.1 0.00022 20.5 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KER25715.1 - 9e-10 38.3 0.0 0.0028 17.5 0.1 3.5 2 2 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER25715.1 - 2.7e-05 24.4 0.0 0.0033 17.7 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER25715.1 - 0.0011 18.8 0.8 0.092 12.6 0.0 3.2 3 1 1 4 4 4 1 EF hand SHOCT PF09851.9 KER25715.1 - 0.0017 18.0 2.7 0.71 9.7 0.3 2.7 2 1 0 2 2 2 2 Short C-terminal domain RST PF12174.8 KER25715.1 - 0.0039 17.1 0.2 0.15 12.0 0.1 2.5 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_13 PF17958.1 KER25715.1 - 0.013 15.3 0.1 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 KER25715.1 - 0.015 15.2 0.3 0.35 10.8 0.1 2.3 3 0 0 3 3 3 0 Caleosin related protein EF-hand_11 PF08976.11 KER25715.1 - 0.041 14.7 0.1 0.43 11.5 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain EFhand_Ca_insen PF08726.10 KER25715.1 - 0.063 13.4 0.2 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand S_100 PF01023.19 KER25715.1 - 2.9 7.7 5.1 3.2 7.5 0.9 2.7 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain RRM_1 PF00076.22 KER25716.1 - 0.00046 19.9 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 KER25716.1 - 0.012 15.2 1.9 0.019 14.6 1.9 1.4 1 0 0 1 1 1 0 Spt20 family ASF1_hist_chap PF04729.13 KER25717.1 - 6.8e-64 214.5 0.0 1.1e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone RRG8 PF17068.5 KER25718.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial RVT_1 PF00078.27 KER25720.1 - 5.3e-38 130.8 0.0 1e-32 113.5 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Rrp15p PF07890.12 KER25720.1 - 3.2e-22 79.3 3.0 5.2e-22 78.6 3.0 1.3 1 0 0 1 1 1 1 Rrp15p TRAM_LAG1_CLN8 PF03798.16 KER25722.1 - 1e-20 74.4 16.7 1e-20 74.4 16.7 1.5 2 0 0 2 2 2 1 TLC domain p25-alpha PF05517.12 KER25723.1 - 7.2e-15 55.5 0.0 8.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 p25-alpha RhoGAP PF00620.27 KER25724.1 - 9.8e-37 126.1 0.0 1.9e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 KER25724.1 - 0.00032 21.0 0.0 0.0008 19.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF1082 PF06449.11 KER25726.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) HhH-GPD PF00730.25 KER25727.1 - 7.1 7.1 9.2 8.8 6.8 0.4 3.4 4 0 0 4 4 4 0 HhH-GPD superfamily base excision DNA repair protein PDEase_I PF00233.19 KER25730.1 - 0.061 13.0 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HTH_41 PF14502.6 KER25730.1 - 0.094 12.4 0.0 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TPX2 PF06886.11 KER25731.1 - 1.4e-13 50.8 14.3 1.4e-13 50.8 14.3 1.7 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) EGF PF00008.27 KER25735.1 - 0.028 14.7 0.6 0.028 14.7 0.6 6.1 5 0 0 5 5 5 0 EGF-like domain EGF_alliinase PF04863.13 KER25735.1 - 0.47 10.9 6.3 0.31 11.5 2.8 2.6 2 0 0 2 2 2 0 Alliinase EGF-like domain cEGF PF12662.7 KER25735.1 - 6.1 6.9 16.2 4.6 7.3 1.8 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like SpoIIE PF07228.12 KER25736.1 - 8e-11 42.2 0.0 1.1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KER25736.1 - 0.00011 21.9 0.1 0.00094 18.9 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KER25736.1 - 0.00038 20.2 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WGR PF05406.15 KER25736.1 - 0.23 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 WGR domain Seipin PF06775.14 KER25737.1 - 5.6e-29 101.7 0.1 6.8e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) CBFD_NFYB_HMF PF00808.23 KER25738.1 - 4.6e-10 39.6 0.4 7e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KER25738.1 - 0.048 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF4800 PF16057.5 KER25739.1 - 0.039 13.2 0.0 0.07 12.4 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) RT_RNaseH PF17917.1 KER25740.1 - 2.5e-21 75.9 0.0 6.7e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER25740.1 - 8e-14 51.5 0.0 2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NAF PF03822.14 KER25740.1 - 0.045 14.0 0.4 0.22 11.7 0.4 2.2 1 0 0 1 1 1 0 NAF domain Dpy-30 PF05186.13 KER25740.1 - 0.17 11.6 0.1 26 4.6 0.0 3.4 3 0 0 3 3 3 0 Dpy-30 motif Syntaxin PF00804.25 KER25741.1 - 3.1e-40 138.0 6.8 3.1e-40 138.0 6.8 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KER25741.1 - 6.9e-15 54.8 2.3 2.4e-14 53.0 2.3 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KER25741.1 - 2e-05 24.9 3.3 2e-05 24.9 3.3 2.3 2 0 0 2 2 2 1 Syntaxin-like protein ETRAMP PF09716.10 KER25741.1 - 0.0054 16.8 0.1 0.011 15.8 0.1 1.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.11 KER25741.1 - 0.018 14.9 0.3 0.038 13.9 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ACDC PF14733.6 KER25741.1 - 0.025 14.9 0.5 3.5 8.0 0.3 3.3 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF5305 PF17231.2 KER25741.1 - 0.032 13.6 3.1 0.55 9.6 0.2 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5305) GNVR PF13807.6 KER25741.1 - 0.038 13.9 1.4 0.31 11.0 1.4 2.3 1 1 0 1 1 1 0 G-rich domain on putative tyrosine kinase KIX PF02172.16 KER25741.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 KIX domain SKA1 PF07160.12 KER25741.1 - 0.065 13.1 6.6 1.3 8.8 1.2 2.4 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Synaptobrevin PF00957.21 KER25741.1 - 0.084 12.7 2.3 0.1 12.4 0.7 2.0 2 0 0 2 2 2 0 Synaptobrevin DUF2207 PF09972.9 KER25741.1 - 0.11 11.3 1.1 0.16 10.7 0.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Tnp_22_trimer PF17489.2 KER25741.1 - 0.14 12.1 1.7 2.6 8.1 0.0 3.5 3 0 0 3 3 3 0 L1 transposable element trimerization domain DUF16 PF01519.16 KER25741.1 - 0.42 11.1 6.2 0.21 12.1 0.8 2.5 1 1 0 2 2 2 0 Protein of unknown function DUF16 SVM_signal PF12113.8 KER25741.1 - 0.42 10.5 2.8 0.93 9.4 2.8 1.5 1 0 0 1 1 1 0 SVM protein signal sequence Sigma_reg_N PF13800.6 KER25741.1 - 0.58 10.5 3.9 1.4 9.2 3.9 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SlyX PF04102.12 KER25741.1 - 2.4 8.8 9.8 8.7 7.0 0.4 3.8 3 2 1 4 4 3 0 SlyX GlutR_dimer PF00745.20 KER25741.1 - 3.7 8.1 8.3 1.4 9.4 1.7 2.5 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CorA PF01544.18 KER25741.1 - 5.3 6.3 13.6 0.3 10.4 1.1 2.8 2 2 1 3 3 3 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.12 KER25741.1 - 6.9 7.2 8.1 11 6.6 0.6 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LisH_TPL PF17814.1 KER25742.1 - 0.13 11.9 0.2 0.36 10.5 0.2 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain eRF1_2 PF03464.15 KER25743.1 - 1.2e-46 158.3 0.0 2e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KER25743.1 - 1.3e-37 128.7 0.1 3.7e-37 127.2 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 KER25743.1 - 1.6e-20 73.4 0.0 2.5e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KER25743.1 - 2.4e-10 40.8 0.0 3.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KER25743.1 - 1.7e-09 38.0 0.0 2.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Lyase_1 PF00206.20 KER25744.1 - 1.4e-89 300.6 0.0 1.1e-88 297.6 0.0 2.0 1 1 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KER25744.1 - 6.8e-20 71.2 0.1 1.8e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF1995 PF09353.10 KER25747.1 - 0.06 13.4 0.0 0.063 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Sugar_tr PF00083.24 KER25749.1 - 0.012 14.5 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Sugar_tr PF00083.24 KER25750.1 - 2.1e-66 224.6 17.5 4.5e-39 134.6 16.4 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 KER25751.1 - 6.2e-100 335.2 21.1 2.1e-98 330.1 21.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER25751.1 - 6.1e-17 61.6 22.8 8.8e-16 57.8 22.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 KER25751.1 - 0.0002 19.8 0.2 0.00042 18.7 0.2 1.5 1 0 0 1 1 1 1 BT1 family Sugar_tr PF00083.24 KER25752.1 - 1e-79 268.5 26.7 3.4e-45 154.8 12.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KER25752.1 - 4.5e-21 75.2 44.0 1.4e-20 73.5 27.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KER25752.1 - 0.0011 17.6 23.4 0.0022 16.6 3.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Phage_holin_3_2 PF04550.12 KER25752.1 - 0.51 10.9 5.3 0.2 12.3 1.5 2.4 2 1 0 2 2 2 0 Phage holin family 2 TssN PF17555.2 KER25752.1 - 0.58 9.5 15.1 0.13 11.6 7.5 2.4 2 0 0 2 2 2 0 Type VI secretion system, TssN PAP_central PF04928.17 KER25754.1 - 2.3e-21 75.9 0.6 6.1e-11 41.8 0.2 3.0 2 1 1 3 3 3 2 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KER25754.1 - 2.3e-07 30.6 0.0 0.00014 21.5 0.0 2.2 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain Lipocalin PF00061.23 KER25755.1 - 2.7e-16 60.1 2.2 3.4e-16 59.7 2.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF3391 PF11871.8 KER25756.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Rhodanese PF00581.20 KER25758.1 - 1.7e-11 44.5 0.0 2.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain TBCC PF07986.12 KER25759.1 - 2e-19 69.5 0.1 5.9e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C Poly_export PF02563.16 KER25759.1 - 0.097 12.9 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein sCache_3_2 PF17203.4 KER25760.1 - 0.045 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Single cache domain 3 CDC45 PF02724.14 KER25761.1 - 0.0057 15.0 7.8 0.0068 14.8 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KER25761.1 - 0.96 7.6 21.0 1.2 7.3 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KER25761.1 - 1.7 7.1 15.5 2.7 6.4 15.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SEP PF08059.13 KER25762.1 - 4.5e-14 52.8 0.0 9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 SEP domain ABC_tran_CTD PF16326.5 KER25762.1 - 0.07 13.4 0.8 0.07 13.4 0.8 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain RVT_1 PF00078.27 KER25763.1 - 1.9e-18 66.8 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4722 PF15849.5 KER25763.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) UNC-79 PF14776.6 KER25764.1 - 3.1e-125 418.9 10.5 6.6e-78 262.7 5.9 3.3 2 1 1 3 3 3 3 Cation-channel complex subunit UNC-79 zf-4CXXC_R1 PF10497.9 KER25764.1 - 1 9.6 4.0 3.9 7.7 4.0 2.0 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MULE PF10551.9 KER25766.1 - 4.4e-21 75.1 0.0 1.1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Prefoldin PF02996.17 KER25766.1 - 3.1e-12 46.5 0.4 7.7e-12 45.2 0.4 1.6 1 0 0 1 1 1 1 Prefoldin subunit RVT_1 PF00078.27 KER25766.1 - 2.7e-10 40.1 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SWIM PF04434.17 KER25766.1 - 0.11 12.2 0.9 0.32 10.7 0.9 1.8 1 0 0 1 1 1 0 SWIM zinc finger PHTB1_N PF14727.6 KER25768.1 - 3.6e-68 230.8 0.0 5.2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 KER25768.1 - 3.8e-10 39.4 0.2 7.7e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 PTHB1 C-terminus MDM1 PF15501.6 KER25769.1 - 3.7e-08 33.0 26.9 9.8e-08 31.6 26.9 1.5 1 1 0 1 1 1 1 Nuclear protein MDM1 Spectrin PF00435.21 KER25769.1 - 0.021 15.3 0.7 0.068 13.7 0.7 1.9 1 0 0 1 1 1 0 Spectrin repeat Siah-Interact_N PF09032.11 KER25769.1 - 0.047 14.0 0.7 0.22 11.9 0.7 2.1 1 0 0 1 1 1 0 Siah interacting protein, N terminal Dynamin_N PF00350.23 KER25769.1 - 0.28 11.2 3.0 0.14 12.2 0.4 1.8 2 0 0 2 2 2 0 Dynamin family Leu_zip PF15294.6 KER25769.1 - 4.9 6.6 8.6 0.1 12.1 1.0 1.9 2 0 0 2 2 2 0 Leucine zipper Ras PF00071.22 KER25770.1 - 3.2e-33 114.6 0.0 1.3e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KER25770.1 - 1.8e-11 44.3 0.0 3.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KER25770.1 - 0.015 15.3 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KER25770.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 KER25770.1 - 0.079 13.3 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KER25770.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KER25770.1 - 0.18 11.5 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KER25770.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SIR2 PF02146.17 KER25771.1 - 6.3e-49 166.3 0.0 5.6e-45 153.4 0.0 2.1 2 0 0 2 2 2 2 Sir2 family RPN13_C PF16550.5 KER25772.1 - 8.3e-24 83.9 0.3 2.1e-23 82.6 0.3 1.7 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KER25772.1 - 1.3e-21 76.9 0.3 2.2e-21 76.2 0.3 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor GATA PF00320.27 KER25774.1 - 1.1e-13 50.5 5.9 1.1e-13 50.5 5.9 2.5 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KER25774.1 - 0.18 11.3 6.1 0.15 11.6 0.9 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding Nop14 PF04147.12 KER25774.1 - 5.4 5.1 17.2 11 4.1 17.2 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KER25774.1 - 6.1 5.0 14.5 9.5 4.4 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KER25774.1 - 6.3 6.0 13.3 0.069 12.5 5.1 1.8 2 0 0 2 2 2 0 BUD22 DnaJ PF00226.31 KER25776.1 - 8.3e-28 96.3 3.6 1.2e-27 95.7 3.6 1.3 1 0 0 1 1 1 1 DnaJ domain Neur_chan_LBD PF02931.23 KER25777.1 - 6.4e-41 140.2 4.2 7.8e-39 133.4 4.2 2.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER25777.1 - 3.1e-11 43.8 8.8 3.1e-11 43.8 8.8 2.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Arf PF00025.21 KER25778.1 - 2.5e-50 170.4 0.0 2.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER25778.1 - 3.3e-12 46.2 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KER25778.1 - 3.7e-11 43.3 0.0 5.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER25778.1 - 9.2e-09 35.1 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KER25778.1 - 1.6e-07 30.9 0.0 0.00026 20.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KER25778.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER25778.1 - 0.00016 21.2 0.0 0.0047 16.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KER25778.1 - 0.0052 15.8 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 KER25778.1 - 0.024 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KER25778.1 - 0.095 12.2 0.1 0.54 9.8 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Metallophos PF00149.28 KER25780.1 - 2.4e-16 60.9 0.0 3.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KER25780.1 - 0.019 14.3 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) DUF4537 PF15057.6 KER25783.1 - 2.1e-06 27.7 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) VWA_2 PF13519.6 KER25783.1 - 0.027 15.1 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 KER25783.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein VWA PF00092.28 KER25783.1 - 0.06 13.6 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Homeobox_KN PF05920.11 KER25785.1 - 2.5e-16 59.3 1.3 1.7e-15 56.6 0.2 2.7 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KER25785.1 - 6.3e-07 29.1 3.7 8.6e-07 28.7 1.8 2.2 2 0 0 2 2 2 1 Homeodomain Cas_Cmr5 PF09701.10 KER25785.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) CUB PF00431.20 KER25786.1 - 4.6e-153 500.1 6.1 1.5e-36 125.1 0.0 6.6 6 1 0 6 6 6 5 CUB domain Astacin PF01400.24 KER25786.1 - 7.2e-70 234.5 0.0 1.5e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 KER25786.1 - 8.6e-19 67.5 27.6 1e-10 41.7 9.9 3.1 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 KER25786.1 - 1.1e-13 51.2 27.0 2.1e-07 31.0 7.6 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain EGF PF00008.27 KER25786.1 - 4.8e-08 33.1 23.0 0.00081 19.6 6.3 2.9 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.20 KER25786.1 - 3.3e-05 23.6 8.1 0.49 10.2 0.2 5.0 5 0 0 5 5 5 2 CUB-like domain EGF_3 PF12947.7 KER25786.1 - 0.00017 21.7 25.5 0.0023 18.1 11.4 2.7 2 0 0 2 2 2 2 EGF domain cEGF PF12662.7 KER25786.1 - 0.00026 20.9 11.1 0.018 14.9 3.7 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like hEGF PF12661.7 KER25786.1 - 0.0036 17.9 19.3 0.14 12.9 4.7 2.9 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 KER25786.1 - 0.063 13.1 0.1 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Matrixin DUF2270 PF10028.9 KER25786.1 - 0.48 10.0 2.0 0.93 9.0 2.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) CBP_BcsO PF17037.5 KER25787.1 - 0.086 13.0 1.9 0.17 12.0 0.5 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Lectin_C PF00059.21 KER25788.1 - 7.5e-86 284.0 11.5 1.3e-14 54.8 0.1 11.0 8 1 2 10 10 10 10 Lectin C-type domain UL45 PF05473.12 KER25788.1 - 1.2e-07 31.6 13.2 0.0062 16.2 0.1 5.4 5 0 0 5 5 5 3 UL45 protein, carbohydrate-binding C-type lectin-like Xlink PF00193.17 KER25788.1 - 0.29 11.5 1.5 12 6.4 0.0 4.1 5 0 0 5 5 5 0 Extracellular link domain GTP1_OBG PF01018.22 KER25790.1 - 5.6e-46 155.9 0.5 8.1e-46 155.4 0.5 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 KER25790.1 - 8.9e-19 67.7 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER25790.1 - 2e-06 27.4 0.0 5.4e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Aa_trans PF01490.18 KER25791.1 - 1.5e-45 155.6 20.5 1.8e-45 155.4 20.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KER25791.1 - 0.00013 21.1 19.9 0.00017 20.7 19.0 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Clr2_transil PF16761.5 KER25792.1 - 0.0052 17.6 0.0 0.15 12.9 0.0 2.1 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 SF1-HH PF16275.5 KER25793.1 - 2.4e-35 121.3 3.7 4.8e-35 120.3 3.7 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KER25793.1 - 1.1e-07 31.5 0.6 2.9e-07 30.2 0.6 1.8 1 1 0 1 1 1 1 KH domain Coiled PF05710.12 KER25793.1 - 0.039 14.8 0.1 0.1 13.4 0.1 1.7 1 0 0 1 1 1 0 Coiled coil TF_Zn_Ribbon PF08271.12 KER25793.1 - 0.13 11.8 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PLAT PF01477.23 KER25797.1 - 1.8e-16 60.7 0.1 1.1e-10 42.1 0.0 3.9 4 0 0 4 4 4 2 PLAT/LH2 domain DCX PF03607.17 KER25797.1 - 2.6e-14 53.1 0.0 1.4e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 Doublecortin IQCJ-SCHIP1 PF15157.6 KER25799.1 - 0.15 11.9 2.0 0.18 11.6 1.5 1.5 1 1 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif JAKMIP_CC3 PF16034.5 KER25799.1 - 0.3 11.0 2.1 0.24 11.3 0.3 1.7 1 1 1 2 2 2 0 JAKMIP CC3 domain Pro_isomerase PF00160.21 KER25803.1 - 5.8e-52 176.1 0.0 9.9e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ANAPC4_WD40 PF12894.7 KER25803.1 - 0.0005 20.3 0.1 1.5 9.2 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER25803.1 - 0.0016 19.2 0.1 21 6.2 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat polyprenyl_synt PF00348.17 KER25804.1 - 1.5e-06 27.5 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Rab5-bind PF09311.11 KER25805.1 - 0.17 11.2 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 Rabaptin-like protein DUF2857 PF11198.8 KER25805.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) RRM_1 PF00076.22 KER25806.1 - 5.9e-43 144.5 0.0 1.4e-24 85.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KER25806.1 - 1.6e-21 77.2 0.7 6.1e-21 75.3 0.0 2.2 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 KER25806.1 - 0.00013 21.9 0.0 0.089 12.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KER25806.1 - 0.00027 20.8 0.0 0.6 10.0 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KER25806.1 - 0.0076 15.8 0.0 1.1 8.8 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KER25806.1 - 0.018 15.3 0.0 8.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF1866 PF08952.11 KER25806.1 - 0.071 12.9 0.0 5.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RRM_7 PF16367.5 KER25806.1 - 0.18 11.9 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif DDRGK PF09756.9 KER25807.1 - 6e-58 195.6 24.8 8.3e-58 195.1 24.8 1.2 1 0 0 1 1 1 1 DDRGK domain SAGA-Tad1 PF12767.7 KER25807.1 - 0.38 10.4 5.4 0.51 10.0 5.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LAP1C PF05609.12 KER25807.1 - 1.5 7.8 14.4 2.4 7.2 14.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4246 PF14033.6 KER25807.1 - 4.1 6.4 8.5 1.6 7.8 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4246) RR_TM4-6 PF06459.12 KER25807.1 - 5.7 6.7 20.9 9.5 6.0 20.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1501 PF07394.12 KER25807.1 - 6.9 5.6 9.3 10 5.1 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) AIP3 PF03915.13 KER25809.1 - 7.9e-15 54.9 1.4 9.8e-15 54.6 1.4 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 SesA PF17107.5 KER25809.1 - 0.029 14.6 1.9 0.32 11.2 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PRKG1_interact PF15898.5 KER25809.1 - 0.043 14.7 6.9 0.2 12.6 3.1 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Golgin_A5 PF09787.9 KER25809.1 - 0.53 9.7 11.8 0.11 11.9 6.4 2.1 1 1 0 2 2 2 0 Golgin subfamily A member 5 DIRP PF06584.13 KER25809.1 - 0.89 9.8 3.7 1.2 9.4 0.7 2.2 2 0 0 2 2 2 0 DIRP DUF1664 PF07889.12 KER25809.1 - 1 9.4 7.1 21 5.2 1.8 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF2730 PF10805.8 KER25809.1 - 2 8.6 4.1 10 6.3 2.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) SKA2 PF16740.5 KER25809.1 - 2.4 8.0 13.3 1.7 8.4 3.1 3.9 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 TSC22 PF01166.18 KER25809.1 - 4.2 7.7 7.8 6.5 7.1 0.0 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Fez1 PF06818.15 KER25809.1 - 4.9 7.6 10.7 33 4.9 10.6 2.1 1 1 0 1 1 1 0 Fez1 Sulfotransfer_4 PF17784.1 KER25810.1 - 4e-61 206.6 0.0 4.7e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER25810.1 - 0.0016 18.8 1.1 0.08 13.3 0.2 2.9 1 1 1 2 2 2 1 Sulfotransferase family Pou PF00157.17 KER25812.1 - 0.042 13.8 0.5 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain RRM_1 PF00076.22 KER25816.1 - 3.5e-06 26.7 0.2 7.2e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KER25816.1 - 0.036 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_3 PF08777.11 KER25816.1 - 0.067 13.2 0.2 0.067 13.2 0.2 2.6 3 0 0 3 3 3 0 RNA binding motif Troponin PF00992.20 KER25818.1 - 3.3e-09 37.2 4.5 3.3e-09 37.2 4.5 2.8 2 1 1 3 3 3 1 Troponin Pkinase PF00069.25 KER25819.1 - 1.3e-47 162.4 0.0 1e-44 152.9 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER25819.1 - 7.1e-23 81.2 0.0 1.6e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER25819.1 - 0.28 9.9 1.5 0.37 9.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Arf PF00025.21 KER25820.1 - 1.6e-30 105.8 0.0 1.9e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER25820.1 - 6.9e-05 22.3 0.0 8.6e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SpoOE-like PF09388.10 KER25820.1 - 0.0026 17.6 0.5 0.004 17.0 0.5 1.3 1 0 0 1 1 1 1 Spo0E like sporulation regulatory protein Gtr1_RagA PF04670.12 KER25820.1 - 0.0077 15.6 0.0 0.0091 15.4 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region UCH PF00443.29 KER25822.1 - 3.8e-53 180.6 2.4 4.8e-53 180.3 2.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER25822.1 - 6e-27 95.1 7.2 8.2e-27 94.6 7.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DHC_N2 PF08393.13 KER25823.1 - 4.6e-137 457.3 11.8 4.6e-137 457.3 11.8 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KER25823.1 - 1.6e-126 421.7 1.3 1.5e-86 290.4 0.0 4.1 4 1 1 5 5 5 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 KER25823.1 - 7.3e-112 373.5 0.0 2.1e-111 372.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER25823.1 - 5.3e-90 300.4 2.0 5.3e-90 300.4 2.0 4.1 4 1 1 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KER25823.1 - 6e-75 251.9 0.2 3.7e-57 193.6 0.0 3.2 2 1 1 3 3 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KER25823.1 - 7.7e-73 243.9 0.3 2.6e-70 235.6 0.2 3.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER25823.1 - 4e-63 212.1 0.1 3.4e-62 209.1 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER25823.1 - 2.2e-49 168.3 8.3 6.8e-49 166.7 8.3 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER25823.1 - 2.6e-46 156.6 0.0 2.1e-43 147.2 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KER25823.1 - 9.8e-30 103.3 0.0 6.2e-29 100.7 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER25823.1 - 9.2e-16 58.1 0.0 0.00021 21.3 0.0 5.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER25823.1 - 4e-15 55.8 0.3 4.2e-13 49.4 0.4 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 KER25823.1 - 2.1e-05 24.9 2.4 0.35 11.3 0.0 5.1 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KER25823.1 - 0.0094 16.3 0.0 7.8 6.9 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KER25823.1 - 0.012 15.9 3.3 3.1 8.1 0.0 4.4 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.6 KER25823.1 - 0.062 13.9 0.0 2.7 8.6 0.1 3.9 4 0 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 KER25823.1 - 0.086 12.7 4.3 0.13 12.2 0.0 3.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KER25823.1 - 0.12 12.0 0.0 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KER25823.1 - 1.1 9.6 0.0 1.1 9.6 0.0 5.0 6 0 0 6 6 5 0 AAA ATPase domain AAA_25 PF13481.6 KER25823.1 - 1.9 8.0 4.3 40 3.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain JmjN PF02375.17 KER25823.1 - 2.9 7.9 4.9 54 3.9 0.1 4.3 4 0 0 4 4 4 0 jmjN domain AAA_33 PF13671.6 KER25823.1 - 7.7 6.7 8.5 11 6.2 0.0 3.9 4 0 0 4 4 2 0 AAA domain DENN PF02141.21 KER25825.1 - 4.6e-27 95.2 2.0 5.9e-13 49.2 0.3 2.5 2 1 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 KER25825.1 - 1e-16 61.4 0.9 2.2e-16 60.3 0.3 2.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 KER25825.1 - 0.55 10.3 3.1 1 9.4 0.7 2.4 2 0 0 2 2 2 0 dDENN domain INTAP PF16617.5 KER25825.1 - 0.64 10.4 3.0 0.83 10.0 0.7 2.1 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Mus7 PF09462.10 KER25826.1 - 0.0064 15.4 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family MFS_1 PF07690.16 KER25827.1 - 3.1e-09 36.2 6.7 0.00018 20.6 0.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KER25827.1 - 0.076 11.9 1.4 0.097 11.5 0.0 1.8 3 0 0 3 3 3 0 Sugar (and other) transporter Arginase PF00491.21 KER25829.1 - 4.2e-35 121.6 0.0 6.6e-35 121.0 0.0 1.3 1 1 0 1 1 1 1 Arginase family MIT_LIKE_ACTX PF17556.2 KER25829.1 - 0.11 13.2 0.1 0.85 10.3 0.1 2.2 2 0 0 2 2 2 0 MIT-like atracotoxin family Nup160 PF11715.8 KER25830.1 - 4.6e-22 78.4 2.5 5.9e-19 68.1 0.7 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 LIX1 PF14954.6 KER25830.1 - 0.14 11.4 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Limb expression 1 zf-HC5HC2H_2 PF13832.6 KER25833.1 - 1.8e-34 118.2 4.1 1.8e-34 118.2 4.1 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KER25833.1 - 4.2e-24 84.6 4.0 4.2e-24 84.6 4.0 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 KER25833.1 - 8e-23 81.6 1.0 8e-23 81.6 1.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Bromodomain PF00439.25 KER25833.1 - 4.3e-17 62.0 0.0 9.7e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KER25833.1 - 7e-14 51.1 3.4 7e-14 51.1 3.4 2.5 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 KER25833.1 - 7e-13 48.8 0.0 2.1e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 KER25833.1 - 1.5e-09 37.6 22.7 1.6e-07 31.1 9.1 2.8 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KER25833.1 - 0.0059 16.5 2.4 0.0059 16.5 2.4 2.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KER25833.1 - 0.33 11.1 15.1 1.5 9.0 4.6 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 KER25833.1 - 0.43 10.9 17.0 0.36 11.2 5.0 3.1 3 0 0 3 3 3 0 C1 domain TES PF08034.11 KER25834.1 - 1.9e-19 69.7 15.5 1.9e-19 69.7 15.5 5.0 4 1 1 5 5 5 2 Trematode eggshell synthesis protein DUF1353 PF07087.11 KER25834.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) TES PF08034.11 KER25835.1 - 4.4e-19 68.5 5.3 4.4e-19 68.5 5.3 6.6 6 2 1 7 7 7 2 Trematode eggshell synthesis protein RRM_1 PF00076.22 KER25837.1 - 0.0027 17.5 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 KER25839.1 - 4.7e-42 144.5 20.5 4e-25 89.0 11.5 3.0 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 KER25839.1 - 5.2e-20 72.4 0.0 1e-19 71.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER25839.1 - 0.0014 18.1 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MTABC_N PF16185.5 KER25839.1 - 3.6 7.0 17.5 1 8.8 14.0 2.0 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region ABC_tran PF00005.27 KER25840.1 - 4.7e-11 43.4 0.0 8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER25840.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KER25840.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit WD40 PF00400.32 KER25841.1 - 3e-22 78.5 5.7 7.7e-08 32.9 1.3 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER25841.1 - 1.9e-07 31.3 0.0 0.00017 21.8 0.0 2.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER25841.1 - 1.1e-06 27.7 0.4 0.0015 17.3 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KER25841.1 - 0.2 10.6 1.6 0.31 10.0 0.7 1.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C13 PF01650.18 KER25842.1 - 4.1e-35 121.5 0.0 8e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase C13 family WD40 PF00400.32 KER25843.1 - 6.1e-10 39.5 6.7 0.00065 20.5 0.3 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.32 KER25845.1 - 9.8e-14 51.5 3.9 9.3e-07 29.5 0.2 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER25845.1 - 5.2e-05 23.5 0.0 0.0064 16.8 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Vps5 PF09325.10 KER25846.1 - 1.2e-64 218.1 20.0 2.7e-41 141.7 3.5 2.2 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 KER25846.1 - 1.8e-22 79.4 0.3 6e-22 77.8 0.1 2.1 2 0 0 2 2 2 1 PX domain DUF4471 PF14740.6 KER25846.1 - 7.9e-05 22.0 5.2 0.074 12.3 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) Arfaptin PF06456.13 KER25846.1 - 0.016 14.8 6.9 0.044 13.3 0.5 2.8 1 1 1 3 3 3 0 Arfaptin-like domain BAR_3_WASP_bdg PF10456.9 KER25846.1 - 0.043 13.3 1.8 0.76 9.2 0.1 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Phage_min_tail PF05939.13 KER25846.1 - 0.16 12.4 0.0 5 7.6 0.0 2.4 2 0 0 2 2 2 0 Phage minor tail protein Streptin-Immun PF11083.8 KER25846.1 - 1.1 9.7 6.3 5.9 7.4 1.5 3.0 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein DCAF15_WD40 PF14939.6 KER25847.1 - 1.2e-06 28.3 0.4 3.1e-06 27.0 0.4 1.7 1 1 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat zf-C2H2_4 PF13894.6 KER25848.1 - 3.6e-08 33.6 23.9 0.0027 18.4 0.4 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KER25848.1 - 1.3e-06 28.5 26.3 0.00027 21.2 0.3 5.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KER25848.1 - 7.3e-06 26.1 14.3 0.098 13.0 1.0 4.0 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KER25848.1 - 7.7e-05 23.4 3.1 0.75 10.5 0.1 3.6 2 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KER25848.1 - 0.0058 16.9 1.3 0.0058 16.9 1.3 3.4 3 0 0 3 3 2 1 Drought induced 19 protein (Di19), zinc-binding DUF1610 PF07754.11 KER25848.1 - 0.015 15.2 4.6 30 4.7 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) zf-MIZ PF02891.20 KER25848.1 - 0.019 14.7 7.1 0.046 13.5 0.1 3.4 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-C2H2_9 PF16293.5 KER25848.1 - 0.022 14.6 2.8 0.14 12.0 0.0 3.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 KER25848.1 - 0.037 14.3 10.0 2.1 8.7 0.2 4.7 3 1 1 4 4 4 0 zinc-ribbon ADK_lid PF05191.14 KER25848.1 - 0.044 13.8 0.2 1.5 8.9 0.1 3.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn-C2H2_12 PF18112.1 KER25848.1 - 0.079 13.4 3.4 35 5.0 0.1 3.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 KER25848.1 - 0.11 13.0 26.6 1.3 9.6 0.3 5.8 6 0 0 6 6 5 0 Zinc-finger double domain zf-met PF12874.7 KER25848.1 - 0.11 12.9 14.1 1.3 9.5 0.8 5.0 5 0 0 5 5 5 0 Zinc-finger of C2H2 type UPF0547 PF10571.9 KER25848.1 - 0.12 12.5 3.4 8.6 6.6 0.6 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.6 KER25848.1 - 0.13 12.6 10.3 0.1 13.0 0.8 3.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 KER25848.1 - 0.27 10.8 6.2 2.5 7.7 0.0 3.0 3 0 0 3 3 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 KER25848.1 - 0.29 10.9 3.0 17 5.3 0.1 2.9 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KER25848.1 - 0.41 10.7 8.3 1 9.4 0.1 4.3 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger zf-C2H2_11 PF16622.5 KER25848.1 - 0.79 9.5 19.3 0.31 10.8 0.5 3.8 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-ribbon_3 PF13248.6 KER25848.1 - 0.89 9.1 5.3 13 5.3 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.6 KER25848.1 - 1.2 9.2 5.3 35 4.4 0.0 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-BED PF02892.15 KER25848.1 - 1.6 8.8 11.9 0.27 11.3 2.7 3.6 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 KER25848.1 - 4.4 7.7 15.2 11 6.4 10.0 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) COesterase PF00135.28 KER25849.1 - 3.1e-31 108.8 0.0 6.3e-31 107.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER25849.1 - 8.6e-08 32.3 0.1 4.1e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Transglut_core3 PF13471.6 KER25849.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2182 PF09948.9 KER25849.1 - 0.062 13.2 0.8 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) Cyclin_N PF00134.23 KER25850.1 - 2.5e-09 37.0 0.4 4.6e-09 36.1 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain GLE1 PF07817.13 KER25850.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein TgMIC1 PF11476.8 KER25850.1 - 0.17 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Arf PF00025.21 KER25851.1 - 5.9e-71 237.5 0.1 6.6e-71 237.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KER25851.1 - 2.1e-13 50.6 0.0 2.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KER25851.1 - 1.5e-12 47.4 0.0 1.7e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KER25851.1 - 4.5e-12 45.9 0.0 4.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KER25851.1 - 1.1e-09 38.0 0.9 2.6e-09 36.7 0.4 1.8 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KER25851.1 - 1.8e-09 37.3 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER25851.1 - 0.00021 21.3 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase HSP70 PF00012.20 KER25851.1 - 0.2 9.8 0.0 0.21 9.7 0.0 1.0 1 0 0 1 1 1 0 Hsp70 protein EF-hand_7 PF13499.6 KER25854.1 - 3.3e-08 33.9 3.7 3.5e-08 33.8 2.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KER25854.1 - 2.3e-07 30.2 3.3 0.001 18.8 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER25854.1 - 0.00038 19.8 0.4 0.00038 19.8 0.4 3.4 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 KER25854.1 - 0.0017 18.1 2.6 0.0026 17.6 1.3 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KER25854.1 - 0.044 13.3 0.2 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 EF hand Myb_DNA-binding PF00249.31 KER25855.1 - 1.5e-13 50.7 0.1 3.7e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KER25855.1 - 4.8e-08 33.1 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 KER25855.1 - 0.039 14.0 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 SLIDE OST3_OST6 PF04756.13 KER25856.1 - 0.02 14.2 1.1 0.031 13.6 1.1 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Rtf2 PF04641.12 KER25856.1 - 0.025 13.9 0.3 0.032 13.6 0.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger tRNA_m1G_MT PF01746.21 KER25857.1 - 8.8e-18 64.7 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RVT_1 PF00078.27 KER25858.1 - 0.036 13.6 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Spherulin4 PF12138.8 KER25858.1 - 0.17 11.5 4.3 0.18 11.4 2.1 2.0 2 1 0 2 2 2 0 Spherulation-specific family 4 DUF4349 PF14257.6 KER25858.1 - 0.18 11.2 10.0 0.48 9.8 10.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3110 PF11360.8 KER25858.1 - 0.29 11.3 2.2 0.94 9.7 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3110) Cytochrom_B562 PF07361.11 KER25858.1 - 5.7 7.7 14.1 0.84 10.3 8.0 2.7 3 0 0 3 3 3 0 Cytochrome b562 Glypican PF01153.19 KER25861.1 - 7.1e-44 150.6 0.0 1.1e-43 150.0 0.0 1.1 1 0 0 1 1 1 1 Glypican CWC25 PF12542.8 KER25862.1 - 9.1e-07 29.7 2.5 9.1e-07 29.7 2.5 3.7 2 2 0 2 2 2 1 Pre-mRNA splicing factor DASH_Duo1 PF08651.10 KER25862.1 - 0.018 14.8 0.4 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 PQ-loop PF04193.14 KER25863.1 - 1.5e-08 34.3 0.4 4.5e-08 32.7 0.4 1.9 1 0 0 1 1 1 1 PQ loop repeat Oxidored_q3 PF00499.20 KER25863.1 - 0.0078 15.9 1.5 0.012 15.3 1.5 1.4 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2157 PF09925.9 KER25863.1 - 0.2 11.5 6.1 0.034 14.0 2.0 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) HMG_box PF00505.19 KER25864.1 - 4.5e-25 87.9 1.4 9.4e-25 86.8 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER25864.1 - 7e-09 36.2 1.4 1.3e-08 35.2 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.25 KER25865.1 - 2.6e-74 249.9 0.0 3.4e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER25865.1 - 2.6e-46 158.0 0.0 3.8e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KER25865.1 - 9.9e-13 48.2 0.0 3.9e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KER25865.1 - 1.1e-06 27.8 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER25865.1 - 1.4e-06 27.9 0.0 4.7e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like DSHCT PF08148.12 KER25865.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 KER25865.1 - 0.017 15.0 0.1 0.32 10.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER25865.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HlyIII PF03006.20 KER25870.1 - 3.5e-66 223.1 23.0 4.9e-66 222.6 23.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related EF-hand_7 PF13499.6 KER25871.1 - 1.5e-14 54.2 0.0 3.8e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER25871.1 - 4.8e-10 38.5 0.1 0.00013 21.6 0.1 3.6 3 2 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER25871.1 - 1.3e-08 33.8 1.9 0.0016 17.8 0.1 4.2 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 KER25871.1 - 1.1e-05 25.7 0.0 0.00058 20.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KER25871.1 - 5.2e-05 23.0 1.3 0.02 14.7 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain pair EFhand_Ca_insen PF08726.10 KER25871.1 - 0.0039 17.3 0.3 0.016 15.3 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SH2_2 PF14633.6 KER25873.1 - 5.2e-74 248.3 0.0 1.2e-73 247.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 KER25873.1 - 1.9e-31 108.5 0.0 5.9e-31 106.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KER25873.1 - 2.4e-26 92.3 0.0 5.2e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KER25873.1 - 1.4e-16 61.0 2.1 3.2e-16 59.8 2.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 KER25873.1 - 4.7e-09 37.0 1.1 1.4e-08 35.5 1.1 2.0 1 0 0 1 1 1 1 HHH domain SPT6_acidic PF14632.6 KER25873.1 - 3.6e-08 33.9 22.7 3.6e-08 33.9 22.7 5.9 3 1 2 5 5 4 1 Acidic N-terminal SPT6 Tex_N PF09371.10 KER25873.1 - 5.6e-08 32.7 0.9 0.0031 17.2 0.0 3.4 3 0 0 3 3 3 2 Tex-like protein N-terminal domain SH2 PF00017.24 KER25873.1 - 3.2e-05 23.9 0.0 9.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 KER25873.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain S1 PF00575.23 KER25873.1 - 0.082 13.3 0.0 0.58 10.5 0.0 2.5 2 0 0 2 2 2 0 S1 RNA binding domain HHH_3 PF12836.7 KER25873.1 - 0.083 13.2 0.0 0.3 11.4 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif TT_ORF2 PF02957.15 KER25873.1 - 2.9 8.8 8.4 12 6.9 8.4 2.1 1 0 0 1 1 1 0 TT viral ORF2 DUF4651 PF15513.6 KER25874.1 - 0.066 13.0 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) CAP_GLY PF01302.25 KER25876.1 - 2e-47 159.1 2.1 6.7e-25 86.9 0.1 2.3 2 0 0 2 2 2 2 CAP-Gly domain CALCOCO1 PF07888.11 KER25876.1 - 0.0001 21.4 53.9 0.027 13.3 27.9 2.7 2 0 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like PspA_IM30 PF04012.12 KER25876.1 - 0.0086 15.7 5.5 0.0086 15.7 5.5 4.4 2 2 2 4 4 4 1 PspA/IM30 family RVT_1 PF00078.27 KER25878.1 - 7.1e-17 61.7 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M1 PF01433.20 KER25878.1 - 2e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KER25878.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KER25878.1 - 0.081 13.3 0.1 3.6 8.0 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats Sushi PF00084.20 KER25879.1 - 3.2e-08 34.1 11.7 1.3e-06 28.8 0.2 4.3 5 0 0 5 5 5 2 Sushi repeat (SCR repeat) Lectin_C PF00059.21 KER25879.1 - 1.9e-06 28.6 0.7 4.9e-06 27.2 0.7 1.7 1 0 0 1 1 1 1 Lectin C-type domain DUF5305 PF17231.2 KER25879.1 - 0.076 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ac76 PF05814.11 KER25879.1 - 0.1 12.6 0.6 0.2 11.7 0.6 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) Pkinase_Tyr PF07714.17 KER25880.1 - 7.1e-59 199.2 0.0 1.5e-58 198.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KER25880.1 - 2.3e-56 188.3 6.3 1.6e-08 35.1 0.0 8.6 7 1 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 KER25880.1 - 5.7e-54 180.1 0.0 4.4e-08 33.1 0.0 8.4 8 0 0 8 8 8 7 Immunoglobulin I-set domain ig PF00047.25 KER25880.1 - 6.8e-37 125.5 1.4 1.3e-06 28.5 0.0 8.2 7 1 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 KER25880.1 - 1.3e-34 118.3 2.2 2.3e-07 31.0 0.0 8.3 8 0 0 8 8 8 5 Immunoglobulin domain Pkinase PF00069.25 KER25880.1 - 8.2e-28 97.5 0.0 2.2e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KER25880.1 - 4.5e-19 68.6 8.8 1.6 9.0 0.0 11.5 8 4 2 10 10 10 7 Immunoglobulin V-set domain Izumo-Ig PF16706.5 KER25880.1 - 9.7e-07 28.8 1.8 0.12 12.5 0.0 6.1 7 1 0 7 7 7 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KER25880.1 - 2e-06 27.3 0.0 3.6 7.2 0.0 5.0 5 1 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 KER25880.1 - 5.6e-05 23.1 4.0 0.33 11.1 0.1 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KER25880.1 - 0.015 15.5 1.8 20 5.5 0.0 4.7 6 0 0 6 6 5 0 T-cell surface glycoprotein CD3 delta chain V-set_2 PF15910.5 KER25880.1 - 0.018 15.2 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 ICOS V-set domain 7tm_2 PF00002.24 KER25880.1 - 0.26 10.5 1.5 0.38 10.0 1.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Peptidase_C15 PF01470.17 KER25882.1 - 1.6e-16 61.1 0.0 2.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Dynamitin PF04912.14 KER25883.1 - 0.037 13.3 6.2 0.057 12.7 0.8 2.2 2 0 0 2 2 2 0 Dynamitin GIT_CC PF16559.5 KER25883.1 - 0.35 10.8 3.9 1.3 8.9 3.9 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_MLP1_2 PF07926.12 KER25883.1 - 0.61 10.2 12.7 0.036 14.1 6.3 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Exo_endo_phos_2 PF14529.6 KER25885.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER25885.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acatn PF13000.7 KER25888.1 - 4.3e-19 68.4 9.3 4.3e-19 68.4 9.3 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 KER25888.1 - 4e-09 35.8 19.2 4e-09 35.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 KER25888.1 - 2.7 8.5 4.7 5.4 7.5 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_M28 PF04389.17 KER25889.1 - 5.7e-38 130.6 0.0 1.1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ER PF01133.17 KER25889.1 - 5.8e-38 128.9 0.0 1.2e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_M20 PF01546.28 KER25889.1 - 0.057 13.1 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Ank_2 PF12796.7 KER25890.1 - 1.4e-10 41.6 0.0 5e-09 36.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER25890.1 - 2.2e-10 40.9 0.0 1.2e-08 35.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KER25890.1 - 8.9e-10 38.6 0.0 0.0018 18.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KER25890.1 - 3.9e-09 36.0 0.0 0.00022 21.4 0.0 3.7 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KER25890.1 - 5.3e-08 33.0 0.0 0.00024 21.3 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PEHE PF15275.6 KER25890.1 - 0.036 14.7 3.9 0.036 14.7 3.9 2.0 2 1 0 2 2 2 0 PEHE domain DUSP PF06337.12 KER25890.1 - 0.051 14.2 0.7 14 6.4 0.0 2.5 2 0 0 2 2 2 0 DUSP domain Gelsolin PF00626.22 KER25891.1 - 1.1e-38 130.9 0.3 1.1e-13 50.8 0.0 4.4 4 0 0 4 4 4 4 Gelsolin repeat Glyco_hydro_8 PF01270.17 KER25891.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Gelsolin PF00626.22 KER25892.1 - 2.1e-37 126.8 0.1 4.7e-14 52.1 0.1 3.4 3 0 0 3 3 3 3 Gelsolin repeat N_formyltrans_C PF18216.1 KER25892.1 - 0.055 13.2 0.1 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Nudix_hydro PF18290.1 KER25893.1 - 1.1e-07 31.7 0.0 3.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Nudix hydrolase domain NUDIX PF00293.28 KER25893.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peptidase_M28 PF04389.17 KER25894.1 - 2.1e-34 119.0 0.0 3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KER25894.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PEN-2 PF10251.9 KER25894.1 - 0.62 10.5 6.0 0.42 11.1 2.2 2.5 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF747 PF05346.11 KER25895.1 - 4.6e-93 312.2 12.3 6e-93 311.8 12.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Ints3 PF10189.9 KER25897.1 - 1e-69 234.3 3.3 7.8e-68 228.1 3.3 2.6 1 1 0 1 1 1 1 Integrator complex subunit 3 zf-XS PF03470.14 KER25897.1 - 1.6 9.1 4.0 1.5 9.2 0.0 3.0 3 0 0 3 3 3 0 XS zinc finger domain EST1 PF10374.9 KER25899.1 - 2.9e-22 79.8 1.3 1e-21 78.0 0.1 2.7 2 0 0 2 2 2 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KER25899.1 - 3.1e-15 56.4 2.6 1.5e-14 54.1 0.1 2.7 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 KER25899.1 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain Tetraspanin PF00335.20 KER25900.1 - 5.2e-29 101.6 11.6 6.9e-29 101.2 11.6 1.2 1 0 0 1 1 1 1 Tetraspanin family WH1 PF00568.23 KER25902.1 - 2.7e-17 62.7 0.0 4.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KER25902.1 - 1.3e-05 25.5 0.0 4.6e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Tfb2 PF03849.14 KER25903.1 - 4.6e-117 391.0 0.0 5.7e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KER25903.1 - 3.1e-24 85.2 0.3 1.2e-23 83.3 0.2 2.1 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KER25903.1 - 0.007 16.5 0.0 0.027 14.6 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RIIa PF02197.17 KER25903.1 - 0.13 11.9 0.1 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit FNIP PF05725.12 KER25905.1 - 0.22 11.7 5.2 7.4 6.8 0.0 3.3 3 0 0 3 3 3 0 FNIP Repeat TPR_1 PF00515.28 KER25906.1 - 1.4e-14 53.1 0.2 7.3e-05 22.4 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER25906.1 - 2.4e-13 49.1 0.6 0.0015 18.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 KER25906.1 - 6.2e-11 42.1 0.6 1.6e-10 40.7 0.6 1.8 1 0 0 1 1 1 1 STI1 domain TPR_11 PF13414.6 KER25906.1 - 4.1e-09 36.0 0.0 0.0039 16.8 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KER25906.1 - 1.2e-06 28.3 0.1 0.05 13.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER25906.1 - 1.4e-06 28.3 0.0 1.5e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat RVT_1 PF00078.27 KER25906.1 - 2e-06 27.5 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_17 PF13431.6 KER25906.1 - 3.2e-06 27.1 0.2 0.13 12.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER25906.1 - 0.00026 21.4 0.2 0.0056 17.2 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER25906.1 - 0.0009 19.8 0.1 0.034 14.8 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER25906.1 - 0.002 18.8 0.3 0.084 13.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER25906.1 - 0.049 13.9 0.1 9 6.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat RNase_T PF00929.24 KER25907.1 - 2.6e-21 76.9 0.0 4.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Dev_Cell_Death PF10539.9 KER25907.1 - 0.038 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Development and cell death domain DSPc PF00782.20 KER25908.1 - 5.4e-34 116.9 0.0 9.3e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 KER25908.1 - 6.6e-10 38.8 0.4 1.2e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 DEK C terminal domain PTPlike_phytase PF14566.6 KER25908.1 - 1.3e-05 25.4 0.1 0.00022 21.4 0.1 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KER25908.1 - 0.0094 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase OTU PF02338.19 KER25908.1 - 0.13 12.8 0.2 0.42 11.1 0.2 1.8 1 1 0 1 1 1 0 OTU-like cysteine protease Ras PF00071.22 KER25909.1 - 2.1e-47 160.8 0.1 2.9e-47 160.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER25909.1 - 3.1e-17 62.9 0.0 4.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER25909.1 - 1.7e-07 30.9 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER25909.1 - 2.2e-06 27.3 0.4 4.3e-06 26.4 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RVT_1 PF00078.27 KER25909.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RsgA_GTPase PF03193.16 KER25909.1 - 0.00042 20.3 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KER25909.1 - 0.0025 17.6 0.1 0.0025 17.6 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KER25909.1 - 0.03 13.8 0.2 0.08 12.5 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KER25909.1 - 0.042 13.9 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.25 KER25910.1 - 9.7e-57 192.3 0.0 1.6e-56 191.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 KER25910.1 - 2.4e-36 124.0 0.0 5.1e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 KER25910.1 - 2.5e-27 95.8 0.0 7.2e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER25910.1 - 5.7e-05 22.6 0.1 0.0003 20.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER25910.1 - 0.00057 18.8 0.0 0.00091 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KER25910.1 - 0.0012 17.9 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER25910.1 - 0.037 13.9 0.2 0.6 10.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family MBOAT PF03062.19 KER25911.1 - 1.4e-23 83.8 24.9 1.5e-23 83.7 23.3 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family GATA PF00320.27 KER25913.1 - 5.3e-05 22.7 0.7 0.00012 21.6 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger FYVE PF01363.21 KER25913.1 - 0.12 12.5 1.9 0.54 10.4 1.9 2.1 1 0 0 1 1 1 0 FYVE zinc finger CodY PF06018.14 KER25913.1 - 6.7 6.2 8.4 0.15 11.6 0.5 2.2 3 0 0 3 3 3 0 CodY GAF-like domain HLH PF00010.26 KER25914.1 - 0.04 13.9 0.0 0.099 12.6 0.0 1.9 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain T-box PF00907.22 KER25914.1 - 0.064 13.5 0.4 0.12 12.6 0.3 1.4 1 1 0 1 1 1 0 T-box Sema PF01403.19 KER25915.1 - 2.3e-19 69.5 0.1 2.7e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Sema domain V-ATPase_C PF03223.15 KER25916.1 - 3.3e-149 497.3 1.6 3.8e-149 497.1 1.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Folliculin PF11704.8 KER25916.1 - 0.029 14.3 0.0 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MP PF01107.18 KER25916.1 - 0.11 12.0 0.3 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 Viral movement protein (MP) Trypsin_2 PF13365.6 KER25917.1 - 3.8e-25 89.5 0.3 8e-25 88.5 0.3 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KER25917.1 - 1.2e-12 48.1 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 KER25917.1 - 1.7e-10 41.1 0.0 3.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER25917.1 - 5.5e-10 38.9 0.0 1.3e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER25917.1 - 9.5e-09 35.5 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KER25917.1 - 0.0041 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KER25917.1 - 0.027 14.8 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_S46 PF10459.9 KER25917.1 - 0.2 10.2 2.3 0.28 9.8 0.3 1.9 2 0 0 2 2 2 0 Peptidase S46 Ada3 PF10198.9 KER25919.1 - 7.5e-12 45.5 1.5 4e-11 43.2 1.8 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Galactosyl_T PF01762.21 KER25920.1 - 1.1e-09 38.4 0.0 1.3e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER25920.1 - 8.2e-06 25.4 0.0 0.00014 21.4 0.0 2.0 1 1 0 1 1 1 1 Fringe-like 2-Hacid_dh_C PF02826.19 KER25921.1 - 4.8e-55 185.7 0.0 6.9e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KER25921.1 - 2.3e-26 92.1 0.0 3.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KER25921.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CBP4 PF07960.11 KER25924.1 - 0.055 13.3 0.5 0.077 12.8 0.5 1.2 1 0 0 1 1 1 0 CBP4 Polysacc_synt_4 PF04669.13 KER25925.1 - 1.9e-14 53.6 0.0 2.5e-06 27.2 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis zf-C2HC_2 PF13913.6 KER25926.1 - 0.092 12.7 1.1 0.24 11.3 1.1 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Methyltransf_25 PF13649.6 KER25927.1 - 2.1e-09 37.9 0.0 4.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KER25927.1 - 2.5e-08 33.7 0.0 3.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KER25927.1 - 2e-06 27.7 0.1 4.6e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER25927.1 - 2.6e-06 28.0 0.0 6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KER25927.1 - 3.2e-06 26.3 0.1 7.8e-06 25.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 KER25927.1 - 1.2e-05 25.2 0.0 4.4e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KER25927.1 - 3e-05 23.6 0.1 5.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KER25927.1 - 0.0017 18.3 0.1 0.0027 17.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KER25927.1 - 0.0027 17.0 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KER25927.1 - 0.026 15.3 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KER25927.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KER25927.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 KER25927.1 - 0.051 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 KER25927.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 IF-2B PF01008.17 KER25928.1 - 6.5e-52 176.5 0.0 8.9e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phosphodiest PF01663.22 KER25928.1 - 1.5e-36 126.8 0.0 2.9e-30 106.0 0.2 3.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KER25928.1 - 1.9e-09 37.4 0.0 0.0013 18.2 0.0 2.9 3 0 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.18 KER25928.1 - 7.1e-07 28.8 0.0 2.8e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KER25928.1 - 0.033 14.3 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Vps35 PF03635.17 KER25928.1 - 0.06 11.9 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 CbiK PF06180.11 KER25928.1 - 0.099 11.9 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) RelB_transactiv PF16181.5 KER25928.1 - 0.36 11.1 1.2 0.45 10.8 0.1 1.7 2 0 0 2 2 2 0 RelB transactivation domain CTD_bind PF04818.13 KER25929.1 - 0.0075 17.1 0.0 0.019 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 KER25929.1 - 0.012 15.2 0.3 0.029 14.0 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KER25929.1 - 0.069 12.9 3.2 0.19 11.5 1.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Rsa3 PF14615.6 KER25929.1 - 0.099 12.2 1.3 0.22 11.1 1.3 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Exo_endo_phos_2 PF14529.6 KER25930.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Mab-21 PF03281.14 KER25931.1 - 1.3e-98 330.0 0.0 1.7e-98 329.6 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein RPEL PF02755.15 KER25932.1 - 5.8 6.8 5.3 33 4.4 1.0 2.8 2 0 0 2 2 2 0 RPEL repeat FERM_C PF09380.10 KER25933.1 - 1.9e-17 63.4 0.6 5e-13 49.3 0.2 2.5 2 0 0 2 2 2 2 FERM C-terminal PH-like domain FERM_M PF00373.18 KER25933.1 - 2.5e-11 44.0 0.2 4.8e-09 36.7 0.1 2.7 2 0 0 2 2 2 2 FERM central domain Flt3_lig PF02947.14 KER25934.1 - 0.0046 17.1 0.5 2.7 8.2 0.1 2.8 2 0 0 2 2 2 2 flt3 ligand BSP PF04450.12 KER25934.1 - 0.0087 15.9 0.3 0.41 10.4 0.1 2.6 2 0 0 2 2 2 1 Peptidase of plants and bacteria MFS_1 PF07690.16 KER25937.1 - 2.7e-06 26.5 56.2 7.3e-05 21.8 11.2 4.3 3 2 1 4 4 4 4 Major Facilitator Superfamily RPS31 PF17067.5 KER25937.1 - 0.0012 18.9 5.4 0.6 10.3 0.3 2.6 2 0 0 2 2 2 2 Ribosomal protein S31e DUF565 PF04483.12 KER25937.1 - 0.044 14.3 3.5 8.9 6.9 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF565) DUF5056 PF16479.5 KER25937.1 - 0.45 10.8 8.3 1.8 8.8 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5056) La PF05383.17 KER25938.1 - 5.5e-20 71.2 0.2 8.6e-20 70.6 0.2 1.3 1 0 0 1 1 1 1 La domain RVT_1 PF00078.27 KER25939.1 - 7.6e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hum_adeno_E3A PF05393.11 KER25940.1 - 0.069 13.1 0.3 0.069 13.1 0.3 1.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DAG1 PF05454.11 KER25940.1 - 0.57 9.5 4.6 1.4 8.3 4.6 1.7 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) His_Phos_1 PF00300.22 KER25942.1 - 1.5e-38 132.4 0.0 1.8e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KER25942.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Pox_E2-like PF04497.12 KER25945.1 - 0.0041 15.6 0.3 0.0046 15.5 0.3 1.1 1 0 0 1 1 1 1 Poxviridae protein NTP_transf_7 PF07984.12 KER25946.1 - 1.6e-106 356.1 0.1 3.2e-82 276.3 0.1 3.1 3 0 0 3 3 3 3 Nucleotidyltransferase rve PF00665.26 KER25946.1 - 1.1e-15 57.9 0.0 4.3e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KER25946.1 - 4.9e-13 49.0 0.4 1.1e-12 47.9 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KER25946.1 - 0.0023 18.1 0.2 0.0075 16.5 0.2 2.0 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 KER25946.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-C2H2_4 PF13894.6 KER25947.1 - 3.3e-17 61.7 57.6 0.013 16.3 0.4 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KER25947.1 - 2.9e-15 55.7 63.7 0.00039 20.7 1.3 10.1 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER25947.1 - 2.1e-11 43.7 52.7 6.5e-06 26.3 1.6 9.7 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_2 PF12756.7 KER25947.1 - 4e-08 33.5 35.2 0.14 12.5 0.3 7.4 1 1 6 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KER25947.1 - 1e-07 32.0 39.0 0.029 14.7 0.0 7.9 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER25947.1 - 1e-05 25.8 27.5 0.016 15.6 0.5 7.0 8 0 0 8 8 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER25947.1 - 3.3e-05 23.7 44.2 0.004 17.1 0.1 8.3 9 0 0 9 9 8 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KER25947.1 - 0.00071 20.3 28.4 0.1 13.3 5.8 4.8 1 1 4 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KER25947.1 - 0.0013 18.9 4.2 0.0013 18.9 4.2 5.9 4 3 2 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 KER25947.1 - 0.016 15.2 0.8 0.016 15.2 0.8 5.7 3 2 2 5 5 5 0 Transcription elongation factor Elf1 like FOXP-CC PF16159.5 KER25947.1 - 0.025 15.2 0.2 0.025 15.2 0.2 5.6 3 2 4 7 7 7 0 FOXP coiled-coil domain zinc_ribbon_15 PF17032.5 KER25947.1 - 0.044 14.5 26.3 0.32 11.8 0.2 5.3 2 1 2 5 5 5 0 zinc-ribbon family DUF629 PF04780.12 KER25947.1 - 0.75 8.2 22.5 2 6.9 0.5 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF629) Zn-C2H2_12 PF18112.1 KER25947.1 - 2.7 8.6 6.4 41 4.8 0.1 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 KER25947.1 - 3 7.7 13.9 2.4 8.1 0.0 5.5 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-NADH-PPase PF09297.11 KER25947.1 - 7.9 6.2 7.6 55 3.5 0.0 4.3 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain PBP1_TM PF14812.6 KER25947.1 - 8.1 6.9 10.8 0.51 10.7 3.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_1 PF00078.27 KER25948.1 - 5.7e-08 32.5 0.0 8.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CSD PF00313.22 KER25949.1 - 2.1e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KER25949.1 - 0.0027 17.4 0.4 0.0072 16.0 0.4 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain HMG_box PF00505.19 KER25953.1 - 4.3e-13 49.5 0.0 8.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box CobT PF06213.12 KER25956.1 - 0.26 10.6 14.7 0.27 10.6 14.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 KER25956.1 - 0.74 7.8 28.1 0.76 7.8 28.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KER25956.1 - 1.1 7.4 16.6 1.2 7.3 16.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER25956.1 - 1.2 7.2 19.4 1.3 7.2 19.4 1.0 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.13 KER25956.1 - 3.8 6.0 13.8 3.7 6.0 13.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2457 PF10446.9 KER25956.1 - 3.8 6.5 31.2 4.4 6.3 31.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KER25956.1 - 6 6.2 20.9 6.5 6.1 20.9 1.0 1 0 0 1 1 1 0 SDA1 QVR PF17064.5 KER25958.1 - 2e-06 27.9 6.1 7.3e-06 26.1 0.6 2.2 1 1 1 2 2 2 2 Sleepless protein DUF753 PF05444.12 KER25958.1 - 0.015 15.3 0.3 0.015 15.3 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF753) Ly-6_related PF06579.12 KER25958.1 - 0.13 12.5 4.0 0.31 11.3 4.0 1.7 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DUF716 PF04819.12 KER25959.1 - 5.8e-06 26.0 4.8 1.5e-05 24.6 4.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF716) CCDC158 PF15921.5 KER25962.1 - 0.011 13.6 2.4 0.016 13.0 2.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Filament PF00038.21 KER25962.1 - 0.014 15.0 2.2 0.021 14.4 2.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Nup88 PF10168.9 KER25962.1 - 0.034 12.0 3.3 0.048 11.5 3.3 1.1 1 0 0 1 1 1 0 Nuclear pore component GDPD PF03009.17 KER25962.1 - 0.1 12.3 0.4 0.3 10.8 0.3 1.8 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family APG6_N PF17675.1 KER25962.1 - 0.11 13.1 3.1 0.19 12.2 3.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4164 PF13747.6 KER25962.1 - 0.22 11.8 4.5 0.98 9.7 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Suppressor_APC PF11414.8 KER25962.1 - 0.34 11.0 2.3 0.69 10.0 2.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein MCC-bdg_PDZ PF10506.9 KER25963.1 - 1.1e-07 31.7 1.3 1.1e-07 31.7 1.3 3.5 3 0 0 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Ctf8 PF09696.10 KER25963.1 - 0.12 12.7 0.4 0.26 11.6 0.4 1.5 1 0 0 1 1 1 0 Ctf8 Takusan PF04822.13 KER25963.1 - 0.18 11.7 4.3 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Takusan CdvA PF18822.1 KER25963.1 - 1.2 9.0 7.3 0.11 12.3 1.2 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Syntaxin_2 PF14523.6 KER25963.1 - 4.1 7.8 7.6 7.3 7.0 2.5 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Hist_deacetyl PF00850.19 KER25964.1 - 9.6e-72 242.0 0.1 3.6e-70 236.9 0.1 3.0 2 1 0 2 2 2 1 Histone deacetylase domain DUF2946 PF11162.8 KER25964.1 - 0.0049 17.5 0.0 0.023 15.3 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Hist_deacetyl PF00850.19 KER25965.1 - 1e-155 517.9 0.1 3.1e-76 256.8 0.1 3.1 2 1 0 2 2 2 2 Histone deacetylase domain zf-UBP PF02148.19 KER25965.1 - 3.6e-32 110.5 16.9 3.4e-19 68.9 9.1 2.8 1 1 1 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KER25965.1 - 0.00011 21.9 3.0 0.0034 17.1 1.4 2.8 2 0 0 2 2 2 1 Variant UBP zinc finger zinc_ribbon_9 PF14369.6 KER25965.1 - 0.42 10.9 10.4 2.9 8.2 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon DUF4452 PF14618.6 KER25965.1 - 3.2 7.6 10.5 0.25 11.2 1.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4452) RVT_1 PF00078.27 KER25966.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ICAM_N PF03921.14 KER25967.1 - 0.02 14.6 0.1 6.2 6.6 0.0 2.2 1 1 1 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain Pkinase_Tyr PF07714.17 KER25972.1 - 6.3e-78 261.6 0.0 8.4e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER25972.1 - 1e-41 143.1 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 KER25972.1 - 0.0021 18.4 0.2 0.0053 17.1 0.2 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KER25972.1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_9 PF14604.6 KER25972.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Kdo PF06293.14 KER25972.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rotamase PF00639.21 KER25976.1 - 6.5e-25 87.9 0.0 1.4e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KER25976.1 - 6.9e-20 71.7 0.0 1.6e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KER25976.1 - 1.2e-11 44.5 0.8 1.2e-11 44.5 0.8 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KER25976.1 - 0.0032 18.3 0.0 0.0079 17.0 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rap_GAP PF02145.15 KER25977.1 - 7.2e-35 120.2 0.0 1.2e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Rhomboid PF01694.22 KER25982.1 - 5e-07 29.8 3.3 5e-07 29.8 3.3 2.8 2 1 0 3 3 3 2 Rhomboid family IFT81_CH PF18383.1 KER25984.1 - 1.1e-47 161.3 0.5 1.1e-47 161.3 0.5 2.3 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain Hemerythrin PF01814.23 KER25984.1 - 0.88 10.2 9.3 0.91 10.1 0.2 3.8 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain Tma16 PF11176.8 KER25984.1 - 1.3 8.8 20.3 0.43 10.4 1.9 3.5 3 0 0 3 3 3 0 Translation machinery-associated protein 16 Matrilin_ccoil PF10393.9 KER25984.1 - 1.7 8.5 10.9 0.31 10.9 0.8 3.9 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF948 PF06103.11 KER25984.1 - 2.4 8.5 18.2 0.14 12.4 0.6 5.1 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 KER25984.1 - 3.5 5.5 25.5 0.8 7.6 7.3 2.9 3 0 0 3 3 3 0 Prominin Zip PF02535.22 KER25985.1 - 1.1e-62 212.2 11.0 1.5e-62 211.7 11.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_L34 PF00468.17 KER25985.1 - 0.017 15.1 0.1 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L34 DUF1772 PF08592.11 KER25985.1 - 0.053 13.8 2.6 0.088 13.1 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) ETRAMP PF09716.10 KER25985.1 - 0.091 12.8 0.1 0.73 9.9 0.1 2.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Guanylate_kin PF00625.21 KER25988.1 - 3e-24 85.7 0.0 4.5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KER25988.1 - 4.3e-08 32.7 0.0 1.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 KER25988.1 - 8e-06 26.1 0.1 1.8e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KER25988.1 - 2.7e-05 23.7 0.2 8.5e-05 22.1 0.2 1.9 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER25988.1 - 0.0018 18.1 0.1 0.0045 16.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KER25988.1 - 0.041 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 PDZ domain Kinesin PF00225.23 KER25990.1 - 3.6e-106 354.9 0.3 3.6e-106 354.9 0.3 2.4 2 2 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KER25990.1 - 9.3e-21 74.3 1.3 3.1e-19 69.4 0.2 3.3 2 1 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KER25990.1 - 3.4e-10 40.4 0.2 3.4e-10 40.4 0.2 4.3 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Mce4_CUP1 PF11887.8 KER25990.1 - 6.5 6.1 13.6 3.4 7.1 0.9 3.7 2 1 1 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative Arf PF00025.21 KER25992.1 - 2.1e-69 232.4 0.3 2.6e-69 232.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KER25992.1 - 2.9e-12 46.5 0.0 3.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER25992.1 - 1.1e-11 45.0 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KER25992.1 - 1.6e-11 44.0 0.6 8.2e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KER25992.1 - 2.9e-10 39.8 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KER25992.1 - 8.7e-09 35.1 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER25992.1 - 8e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KER25992.1 - 0.0033 16.9 0.1 0.0055 16.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 KER25992.1 - 0.035 13.7 0.0 0.32 10.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Cnd3 PF12719.7 KER25994.1 - 4.5e-36 124.5 1.4 1e-33 116.8 0.2 3.1 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KER25994.1 - 1.5e-11 44.5 4.7 0.00021 21.6 0.0 5.3 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KER25994.1 - 2.3e-06 27.3 12.6 5.7 7.5 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat UVR PF02151.19 KER25994.1 - 7.2e-06 25.6 0.1 1.9e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Cnd1 PF12717.7 KER25994.1 - 4.2e-05 23.7 2.1 1.1 9.3 0.0 4.4 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KER25994.1 - 0.096 12.2 0.1 1.2 8.7 0.2 2.7 1 1 0 1 1 1 0 CLASP N terminal Cas9_Topo PF17894.1 KER25995.1 - 0.0024 17.9 0.0 0.013 15.5 0.0 2.2 3 0 0 3 3 3 1 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Pkinase_Tyr PF07714.17 KER25997.1 - 2e-53 181.3 0.0 3.2e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER25997.1 - 1e-49 169.3 0.0 1.5e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KER25997.1 - 3.7e-06 26.0 0.0 7.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TPR_12 PF13424.6 KER25999.1 - 0.00012 22.3 0.6 0.041 14.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER25999.1 - 0.0078 16.3 0.1 1.4 9.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 KER25999.1 - 0.032 13.7 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP RTP1_C1 PF10363.9 KER26002.1 - 1.5e-30 105.7 0.0 5.9e-30 103.7 0.0 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 KER26002.1 - 7.1e-08 32.7 0.5 0.00011 22.5 0.0 3.8 2 1 0 2 2 2 1 HEAT repeats ThaI PF15514.6 KER26002.1 - 2.7e-07 30.4 0.0 1.2 8.8 0.0 3.3 3 0 0 3 3 3 3 Restriction endonuclease ThaI HEAT PF02985.22 KER26002.1 - 1.1e-05 25.3 0.1 4.2 7.9 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KER26002.1 - 1.2e-05 25.4 0.1 0.031 14.3 0.0 3.9 4 0 0 4 4 3 2 non-SMC mitotic condensation complex subunit 1 DNA_ligase_OB PF03120.16 KER26002.1 - 0.00024 21.0 1.5 2.9 7.9 0.0 3.5 3 0 0 3 3 3 2 NAD-dependent DNA ligase OB-fold domain YjbT PF17089.5 KER26002.1 - 0.0068 16.4 0.0 26 4.9 0.0 3.9 3 0 0 3 3 3 0 Uncharacterised protein family Barttin PF15462.6 KER26002.1 - 0.015 15.1 12.5 3.4 7.4 0.5 3.3 3 0 0 3 3 3 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF3148 PF11347.8 KER26002.1 - 0.017 14.9 0.1 87 3.0 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3148) R2K_2 PF18299.1 KER26002.1 - 0.017 15.0 0.1 60 3.5 0.0 3.4 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 2 Vac14_Fab1_bd PF12755.7 KER26002.1 - 0.041 14.5 0.0 1.7 9.3 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF792 PF05632.11 KER26002.1 - 0.054 13.4 0.1 85 2.9 0.0 3.3 3 0 0 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF792) Med14 PF08638.11 KER26002.1 - 0.12 11.8 0.0 26 4.2 0.0 3.2 3 0 0 3 3 3 0 Mediator complex subunit MED14 Pkinase PF00069.25 KER26005.1 - 8.4e-64 215.5 0.1 1.8e-63 214.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26005.1 - 2.8e-16 59.6 0.0 5.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER26005.1 - 2.2e-07 31.0 0.0 3.1e-05 24.0 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KER26005.1 - 0.0064 15.3 1.6 0.019 13.7 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 KER26005.1 - 0.018 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5044 PF16447.5 KER26005.1 - 0.018 14.9 0.1 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) Choline_kinase PF01633.20 KER26005.1 - 0.032 13.8 0.1 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase SARS_3b PF12383.8 KER26005.1 - 0.047 13.8 3.4 13 5.9 0.1 3.7 4 0 0 4 4 4 0 Severe acute respiratory syndrome coronavirus 3b protein FTA2 PF13095.6 KER26005.1 - 0.082 12.5 2.1 2 8.0 0.0 3.3 3 1 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 zf-CCHC_4 PF14392.6 KER26005.1 - 0.85 9.4 5.9 0.34 10.7 2.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 KER26007.1 - 5.1e-63 212.9 0.1 6.2e-63 212.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26007.1 - 1.8e-17 63.5 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER26007.1 - 1e-06 28.8 1.0 4.2e-06 26.9 0.2 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KER26007.1 - 4.7e-06 26.1 0.2 7.3e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KER26007.1 - 0.0052 16.4 0.1 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KER26007.1 - 0.0069 15.2 0.2 0.012 14.4 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase MgtE_N PF03448.17 KER26007.1 - 0.031 14.9 0.2 8.1 7.1 0.0 2.8 4 0 0 4 4 4 0 MgtE intracellular N domain DUF2459 PF09601.10 KER26007.1 - 0.1 12.4 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Cadherin PF00028.17 KER26010.1 - 1.5e-57 192.0 0.8 1.7e-09 38.0 0.4 10.5 9 1 0 9 9 9 8 Cadherin domain Cadherin_2 PF08266.12 KER26010.1 - 9.4e-05 22.2 0.0 0.0038 17.0 0.0 2.9 2 0 0 2 2 2 1 Cadherin-like AAA_25 PF13481.6 KER26010.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPA PF17217.3 KER26013.1 - 4e-32 111.0 0.0 7.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KER26013.1 - 2.8e-20 72.5 0.0 6.6e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain Ig_3 PF13927.6 KER26013.1 - 1.5e-13 51.1 0.1 1.1e-12 48.4 0.0 2.6 3 0 0 3 3 2 1 Immunoglobulin domain I-set PF07679.16 KER26013.1 - 1.2e-12 47.7 0.0 4.5e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER26013.1 - 1.5e-09 38.0 0.0 1.4e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KER26013.1 - 2.7e-08 33.9 0.0 2.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain Death PF00531.22 KER26013.1 - 0.0001 22.4 0.1 0.00028 21.0 0.1 1.7 1 0 0 1 1 1 1 Death domain C2-set_2 PF08205.12 KER26013.1 - 0.0019 18.2 0.0 0.0092 16.0 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KER26013.1 - 0.0024 18.0 0.1 1.6 8.9 0.1 2.9 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_5 PF16681.5 KER26013.1 - 0.057 13.8 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain MRAP PF15183.6 KER26013.1 - 0.18 11.8 0.0 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family NAD_kinase PF01513.21 KER26014.1 - 1.4e-06 27.8 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 KER26014.1 - 0.047 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 KER26015.1 - 3.1e-34 118.5 0.0 4.5e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26015.1 - 4.4e-30 104.8 0.0 5.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER26015.1 - 0.00024 21.1 0.0 0.00073 19.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cir_N PF10197.9 KER26016.1 - 8.8e-09 35.4 7.7 8.8e-09 35.4 7.7 5.9 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCCH PF00642.24 KER26017.1 - 1.4e-11 44.0 20.9 2.5e-06 27.3 4.0 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KER26017.1 - 8.8e-07 28.7 0.1 5.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KER26017.1 - 8.4e-05 22.5 13.0 0.043 13.9 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KER26017.1 - 0.00058 20.5 8.2 0.091 13.5 0.1 2.6 2 1 0 2 2 2 2 Torus domain Nup35_RRM_2 PF14605.6 KER26017.1 - 0.0076 16.2 0.5 0.058 13.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Attractin PF08037.11 KER26017.1 - 0.06 13.4 1.0 16 5.6 0.1 2.6 2 0 0 2 2 2 0 Attractin family zf-CCCH_3 PF15663.5 KER26017.1 - 0.099 12.9 7.0 0.6 10.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 KER26019.1 - 0.00062 19.6 0.8 0.0012 18.7 0.1 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBFB_NFYA PF02045.15 KER26019.1 - 0.023 15.3 5.7 0.034 14.8 5.7 1.3 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hydrolase PF00702.26 KER26020.1 - 0.018 15.4 0.0 0.034 14.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Apo-CIII PF05778.12 KER26020.1 - 0.04 13.5 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Med3 PF11593.8 KER26023.1 - 0.81 8.8 3.6 1.2 8.3 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ELMO_CED12 PF04727.13 KER26026.1 - 6.3e-12 46.0 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KER26026.1 - 0.00071 20.1 0.4 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain His_kinase PF06580.13 KER26026.1 - 0.09 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase Pkinase PF00069.25 KER26028.1 - 6.2e-71 238.8 0.0 7.3e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26028.1 - 1.2e-33 116.5 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER26028.1 - 3.4e-08 33.1 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER26028.1 - 0.00024 20.2 0.1 0.00032 19.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Ras PF00071.22 KER26029.1 - 2.5e-45 154.0 0.1 1.2e-43 148.6 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER26029.1 - 3.3e-25 88.6 0.1 5.5e-24 84.7 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER26029.1 - 6.2e-09 35.5 0.5 6.9e-08 32.1 0.5 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER26029.1 - 0.0015 17.9 0.0 0.002 17.6 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER26029.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KER26029.1 - 0.05 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KER26029.1 - 0.096 12.6 0.1 5.5 6.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KER26029.1 - 0.16 12.3 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MIP PF00230.20 KER26030.1 - 7.4e-40 137.1 1.8 8.4e-40 136.9 1.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2583 PF10762.9 KER26030.1 - 0.035 14.5 0.5 0.44 11.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF347 PF03988.12 KER26030.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.1 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Pep1_7 PF17232.2 KER26030.1 - 0.14 12.6 0.0 0.74 10.3 0.0 2.0 2 1 0 2 2 2 0 Elicitor peptide 1-7 EF-hand_7 PF13499.6 KER26035.1 - 1.4e-09 38.3 1.0 3e-09 37.2 1.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER26035.1 - 2.5e-07 29.8 2.5 0.0033 16.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER26035.1 - 3.6e-07 29.4 3.2 0.016 14.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER26035.1 - 4.4e-07 29.3 1.3 0.0029 17.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KER26035.1 - 0.00011 21.9 5.2 0.0026 17.6 1.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair 14-3-3 PF00244.20 KER26036.1 - 7.5e-82 274.1 5.6 1.1e-81 273.6 5.6 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF4168 PF13767.6 KER26036.1 - 0.0078 17.4 0.6 0.19 13.0 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4168) DUF4795 PF16043.5 KER26036.1 - 1.2 8.8 5.4 16 5.0 5.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SH3BGR PF04908.15 KER26038.1 - 3.5e-22 78.4 0.0 4.9e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KER26038.1 - 0.00069 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Clr2_transil PF16761.5 KER26040.1 - 0.00075 20.3 0.6 0.17 12.8 0.4 2.6 2 0 0 2 2 2 2 Transcription-silencing protein, cryptic loci regulator Clr2 Ig_3 PF13927.6 KER26041.1 - 8.5e-11 42.3 0.1 0.0063 17.1 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KER26041.1 - 1.8e-08 34.3 0.0 0.018 15.1 0.0 4.2 3 1 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 KER26041.1 - 1.9e-06 28.1 0.0 0.22 11.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 KER26041.1 - 3e-05 24.0 0.1 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 KER26041.1 - 0.00013 22.1 0.0 2 8.6 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin domain V-set PF07686.17 KER26041.1 - 0.0026 17.9 0.0 0.057 13.6 0.0 2.7 3 1 0 3 3 3 1 Immunoglobulin V-set domain DNA_pol_phi PF04931.13 KER26041.1 - 0.013 13.7 23.1 0.018 13.2 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER26041.1 - 0.019 14.4 8.3 0.027 13.9 8.3 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 KER26041.1 - 0.026 13.0 3.8 0.035 12.6 3.8 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 KER26041.1 - 0.057 13.0 6.2 0.098 12.2 6.2 1.3 1 0 0 1 1 1 0 PPP4R2 BiPBP_C PF06832.12 KER26041.1 - 0.095 12.8 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family CDC45 PF02724.14 KER26041.1 - 0.37 9.0 11.7 0.54 8.5 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KER26041.1 - 1.1 8.6 10.2 1.5 8.1 10.2 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 KER26041.1 - 1.1 8.6 9.4 1.8 7.9 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 KER26041.1 - 1.7 6.8 3.5 2.3 6.4 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TRAP_alpha PF03896.16 KER26041.1 - 4.2 6.5 6.0 6.7 5.8 6.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KER26041.1 - 5.5 5.1 16.9 7.8 4.6 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KER26041.1 - 6.1 6.7 15.3 10 5.9 15.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PAW PF04721.17 KER26044.1 - 1.3e-37 129.5 0.0 5.1e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin PF00085.20 KER26044.1 - 5.1e-17 61.7 0.3 1.1e-16 60.7 0.3 1.6 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 KER26044.1 - 4.1e-05 24.0 1.7 4.5e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Thioredoxin_8 PF13905.6 KER26044.1 - 0.11 12.8 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.7 KER26045.1 - 3.5e-09 36.4 4.0 6.5e-09 35.5 4.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER26045.1 - 7e-07 29.0 0.9 1.5e-06 28.0 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KER26046.1 - 4.6e-05 23.2 3.2 0.00012 21.9 3.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER26046.1 - 0.00026 20.8 0.7 0.00065 19.5 0.7 1.7 1 0 0 1 1 1 1 F-box domain DUF4508 PF14969.6 KER26046.1 - 0.051 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Pkinase PF00069.25 KER26049.1 - 6.7e-41 140.4 0.0 3.3e-40 138.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26049.1 - 1.5e-17 63.8 0.1 1.6e-16 60.4 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KER26049.1 - 0.038 13.6 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Exo_endo_phos_2 PF14529.6 KER26049.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase APH PF01636.23 KER26049.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBDa PF16564.5 KER26049.1 - 0.18 12.0 5.0 0.49 10.6 5.0 1.8 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Arm PF00514.23 KER26054.1 - 7.3e-17 60.8 14.8 0.0054 16.7 0.0 8.0 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 KER26054.1 - 5.3e-09 36.2 7.9 0.0016 18.4 0.0 5.2 4 1 1 5 5 5 3 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 KER26054.1 - 0.009 16.2 3.1 1.2 9.3 0.0 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KER26054.1 - 0.011 15.8 4.4 2.5 8.1 0.0 4.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KER26054.1 - 0.06 11.9 10.6 0.13 10.8 1.9 3.4 1 1 2 3 3 3 0 Adaptin N terminal region Proteasom_PSMB PF10508.9 KER26054.1 - 0.064 11.8 1.8 3.5 6.0 0.0 2.7 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 KER26054.1 - 0.077 13.3 4.2 19 5.9 0.0 5.9 7 0 0 7 7 7 0 HEAT repeat WD40 PF00400.32 KER26055.1 - 0.048 14.6 0.9 0.75 10.8 0.1 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat RVT_1 PF00078.27 KER26057.1 - 4.4e-08 32.9 0.0 6.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1907 PF08925.11 KER26058.1 - 6.3e-81 271.9 0.0 7.6e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) ANAPC4_WD40 PF12894.7 KER26060.1 - 2.1e-09 37.6 0.0 9e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KER26060.1 - 0.0007 19.2 0.3 0.0094 15.5 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 KER26060.1 - 0.0012 19.6 5.5 6.9 7.7 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 KER26060.1 - 0.025 13.9 0.0 7.5 5.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain BBS2_Mid PF14783.6 KER26060.1 - 0.065 13.3 0.3 8.3 6.5 0.0 3.1 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region APP_N PF02177.16 KER26061.1 - 0.0029 17.9 0.0 0.0082 16.5 0.0 1.7 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding GLTP PF08718.11 KER26062.1 - 1.1e-33 116.6 0.1 1.4e-32 113.0 0.0 2.4 2 1 0 2 2 2 1 Glycolipid transfer protein (GLTP) RVT_1 PF00078.27 KER26063.1 - 2.4e-05 23.9 0.0 6.4e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHHC PF01529.20 KER26064.1 - 1.5e-06 28.4 2.2 3.1e-06 27.3 2.2 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase IMPDH PF00478.25 KER26069.1 - 9.4e-133 442.5 3.0 1.1e-132 442.3 3.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KER26069.1 - 3.9e-12 46.4 0.0 6.2e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KER26069.1 - 1.4e-09 37.8 1.2 3.8e-06 26.5 1.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KER26069.1 - 1.8e-07 30.5 1.8 1.8e-07 30.5 1.8 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KER26069.1 - 7.5e-06 25.6 1.7 0.0017 17.9 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.14 KER26069.1 - 0.0062 15.9 1.2 0.012 14.9 1.2 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 KER26069.1 - 0.012 14.8 1.9 0.031 13.5 1.4 2.0 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Pkinase_Tyr PF07714.17 KER26070.1 - 2.9e-83 279.1 0.0 2.3e-66 223.7 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KER26070.1 - 9.1e-40 136.7 0.0 1.2e-29 103.5 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain SIKE PF05769.11 KER26071.1 - 1.2e-30 106.8 1.8 2.8e-30 105.6 1.8 1.6 1 1 0 1 1 1 1 SIKE family Herpes_BLRF2 PF05812.12 KER26071.1 - 0.0034 17.5 5.7 1.1 9.4 0.0 3.7 4 1 0 4 4 4 2 Herpesvirus BLRF2 protein Imm7 PF15585.6 KER26071.1 - 0.02 15.1 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 Shugoshin_N PF07558.11 KER26071.1 - 1.3 8.9 11.2 0.42 10.5 0.6 3.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Lactamase_B_6 PF16661.5 KER26072.1 - 3.8e-55 186.3 0.0 8.9e-55 185.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KER26072.1 - 4.8e-32 111.5 0.0 8.6e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KER26072.1 - 1.1e-19 70.8 0.0 1.5e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 Beta-Casp domain Peptidase_M18 PF02127.15 KER26072.1 - 0.0012 17.7 0.4 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Lactamase_B_2 PF12706.7 KER26072.1 - 0.0069 15.9 0.3 0.025 14.1 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 KER26072.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CHDCT2 PF08074.11 KER26073.1 - 1.1e-89 299.1 0.7 1.8e-73 246.3 0.2 3.0 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain SNF2_N PF00176.23 KER26073.1 - 2e-57 194.5 0.0 6.8e-57 192.8 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.11 KER26073.1 - 1.2e-45 154.8 0.0 3.1e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 KER26073.1 - 8.2e-26 89.8 4.5 8.2e-26 89.8 4.5 2.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) CHDNT PF08073.12 KER26073.1 - 9.4e-20 70.3 0.9 6.1e-19 67.7 0.6 2.4 2 0 0 2 2 2 1 CHDNT (NUC034) domain Helicase_C PF00271.31 KER26073.1 - 2.9e-19 69.5 0.0 2.9e-19 69.5 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KER26073.1 - 1.9e-18 66.1 26.0 2.9e-10 39.9 7.8 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.24 KER26073.1 - 6.3e-17 61.2 0.7 2.3e-12 46.6 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KER26073.1 - 1.1e-09 38.5 0.0 5.1e-09 36.4 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KER26073.1 - 7.3e-06 25.3 0.0 2.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-HC5HC2H_2 PF13832.6 KER26073.1 - 0.013 15.7 6.4 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain AAA_22 PF13401.6 KER26073.1 - 0.026 14.8 2.1 0.1 12.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain SLIDE PF09111.10 KER26073.1 - 0.038 14.0 0.1 5.2 7.1 0.0 3.0 2 0 0 2 2 2 0 SLIDE PHD_2 PF13831.6 KER26073.1 - 0.14 11.7 11.2 0.45 10.1 2.7 2.7 2 0 0 2 2 2 0 PHD-finger zf-ISL3 PF14690.6 KER26073.1 - 0.41 11.3 4.7 1 10.1 0.6 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-PHD-like PF15446.6 KER26073.1 - 1 9.0 10.1 6.8 6.3 0.9 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KER26073.1 - 1.5 8.7 14.1 2 8.4 1.2 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WRW PF10206.9 KER26074.1 - 1.4e-33 115.3 0.1 2.5e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Ephrin_lbd PF01404.19 KER26075.1 - 6.6e-13 49.1 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Ephrin_rec_like PF07699.13 KER26075.1 - 5e-07 29.4 9.4 7.7e-06 25.6 10.4 2.4 1 1 1 2 2 2 1 Putative ephrin-receptor like Ketoacyl-synt_2 PF13723.6 KER26075.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain zf-C4 PF00105.18 KER26075.1 - 0.096 13.2 0.8 0.096 13.2 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) NCD3G PF07562.14 KER26075.1 - 0.23 11.5 5.1 0.3 11.1 2.5 2.2 1 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF2318 PF10080.9 KER26075.1 - 0.3 11.2 3.9 0.68 10.1 3.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) EGF_MSP1_1 PF12946.7 KER26075.1 - 5.1 7.2 7.4 21 5.3 1.7 3.2 2 1 0 2 2 2 0 MSP1 EGF domain 1 DUF4064 PF13273.6 KER26076.1 - 0.0038 17.5 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) EGF_CA PF07645.15 KER26077.1 - 2.8e-85 280.3 157.8 3e-11 43.3 9.8 15.1 13 2 0 13 13 13 11 Calcium-binding EGF domain cEGF PF12662.7 KER26077.1 - 3.2e-40 135.7 93.7 4.7e-06 26.4 1.6 13.8 14 1 0 14 14 14 11 Complement Clr-like EGF-like EGF_3 PF12947.7 KER26077.1 - 1e-10 41.6 110.8 0.0042 17.3 6.0 13.1 11 2 0 11 11 11 7 EGF domain EGF PF00008.27 KER26077.1 - 4e-09 36.6 102.9 0.0098 16.2 0.8 14.0 14 0 0 14 14 14 6 EGF-like domain hEGF PF12661.7 KER26077.1 - 0.0029 18.2 9.9 0.0066 17.0 2.5 16.2 17 1 0 17 17 17 7 Human growth factor-like EGF FXa_inhibition PF14670.6 KER26077.1 - 0.0041 17.4 4.1 0.0041 17.4 4.1 15.4 13 2 1 14 14 14 6 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 KER26077.1 - 0.0043 17.1 5.1 0.0043 17.1 5.1 10.6 11 0 0 11 11 11 5 MSP1 EGF domain 1 Aldolase_II PF00596.21 KER26078.1 - 1.1e-40 139.6 0.4 1.8e-40 138.9 0.4 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase_Tyr PF07714.17 KER26080.1 - 4e-85 285.2 0.0 6.8e-85 284.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER26080.1 - 4.4e-39 134.4 0.0 7.5e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RD3 PF14473.6 KER26080.1 - 0.061 13.2 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 RD3 protein Ephrin_lbd PF01404.19 KER26083.1 - 4.2e-11 43.2 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain LUC7 PF03194.15 KER26084.1 - 1.5e-85 286.9 5.3 2.1e-85 286.4 5.3 1.2 1 0 0 1 1 1 1 LUC7 N_terminus kleA_kleC PF17383.2 KER26084.1 - 0.014 15.7 0.9 0.052 13.9 0.3 2.2 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A NUDE_C PF04880.13 KER26085.1 - 2.4 8.6 8.3 1.3 9.5 4.3 2.1 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Coatomer_E PF04733.14 KER26086.1 - 2.1e-17 63.5 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit Gag_p30 PF02093.16 KER26086.1 - 0.14 11.6 0.0 2.9 7.3 0.0 2.1 1 1 1 2 2 2 0 Gag P30 core shell protein ATP-synt_ab PF00006.25 KER26087.1 - 4.4e-69 232.4 0.0 7.2e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KER26087.1 - 5e-14 52.6 0.6 8.8e-14 51.8 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain IP_trans PF02121.18 KER26088.1 - 6e-103 343.7 0.0 6.8e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2505 PF10698.9 KER26088.1 - 0.00048 20.3 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2505) DUF2559 PF10832.8 KER26088.1 - 0.022 14.8 1.3 0.044 13.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Mor PF08765.11 KER26088.1 - 0.27 11.3 1.0 0.53 10.3 1.0 1.4 1 0 0 1 1 1 0 Mor transcription activator family Toxin_TOLIP PF00087.21 KER26095.1 - 0.28 11.5 11.9 0.53 10.6 11.9 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein C1_1 PF00130.22 KER26095.1 - 5.1 7.1 8.2 1.5 8.8 1.7 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF960 PF06124.11 KER26098.1 - 0.11 13.1 0.0 18 6.0 0.0 2.3 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Tricorn_PDZ PF14685.6 KER26103.1 - 0.076 13.0 0.0 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain FHIPEP PF00771.20 KER26103.1 - 0.16 10.4 2.7 6.2 5.1 0.2 2.3 2 0 0 2 2 2 0 FHIPEP family DUF89 PF01937.19 KER26105.1 - 0.084 11.8 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF4612 PF15389.6 KER26111.1 - 1.3 10.0 7.1 2.2 9.3 7.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4612) DUF5435 PF17503.2 KER26111.1 - 2.3 7.9 5.1 2.8 7.6 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) TEBP_beta PF07404.11 KER26113.1 - 2.8 7.2 8.4 1.9 7.8 0.1 2.0 1 1 1 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) ALG11_N PF15924.5 KER26116.1 - 9.6e-72 241.4 0.0 1.4e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KER26116.1 - 3.8e-21 75.4 0.0 6.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KER26116.1 - 4.3e-11 43.4 0.0 8.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Asp_protease_2 PF13650.6 KER26116.1 - 2.2e-05 25.0 0.0 0.43 11.3 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KER26116.1 - 0.00057 20.4 0.0 1.1 9.9 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 KER26116.1 - 0.037 14.3 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Apocytochr_F_N PF16639.5 KER26116.1 - 0.16 12.2 1.9 13 6.1 0.1 2.5 1 1 1 2 2 2 0 Apocytochrome F, N-terminal HA2 PF04408.23 KER26117.1 - 1.2e-17 64.1 0.0 1.2e-17 64.1 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KER26117.1 - 9.2e-11 42.1 0.0 4.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER26117.1 - 1.8e-09 37.6 0.2 6e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KER26117.1 - 1e-05 25.8 0.0 5.6e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KER26117.1 - 0.00011 22.4 0.3 0.00052 20.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KER26117.1 - 0.00088 19.0 0.0 0.0023 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KER26117.1 - 0.002 18.4 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER26117.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 KER26117.1 - 0.012 16.2 5.6 3.3 8.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 KER26117.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KER26117.1 - 0.054 13.5 0.6 3.6 7.6 0.6 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KER26117.1 - 0.066 13.3 0.1 3.3 7.8 0.1 3.1 3 1 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 KER26117.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain RVT_1 PF00078.27 KER26118.1 - 2.2e-18 66.6 0.0 4.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MAD PF05557.13 KER26118.1 - 0.0013 17.2 14.5 0.0023 16.4 14.5 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4201 PF13870.6 KER26118.1 - 0.0031 17.3 11.1 0.0094 15.7 11.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) GAS PF13851.6 KER26118.1 - 0.0058 16.0 8.5 0.015 14.7 8.5 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KER26118.1 - 0.011 15.8 7.3 0.04 14.0 7.3 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 BRE1 PF08647.11 KER26118.1 - 0.026 14.6 12.6 0.014 15.5 9.7 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.6 KER26118.1 - 0.052 13.6 9.8 0.11 12.5 9.8 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Hrs_helical PF12210.8 KER26118.1 - 0.072 13.6 4.4 0.2 12.2 4.4 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF724 PF05266.14 KER26118.1 - 0.074 12.9 3.7 0.15 11.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IFT57 PF10498.9 KER26118.1 - 0.085 11.8 6.4 0.16 10.9 6.4 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KER26118.1 - 0.1 12.0 12.2 0.2 11.1 12.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KER26118.1 - 0.2 10.5 13.2 0.45 9.4 13.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KER26118.1 - 0.44 10.1 8.7 0.81 9.2 8.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-H PF05837.12 KER26118.1 - 0.83 10.1 13.6 0.07 13.5 8.0 2.1 2 0 0 2 2 1 0 Centromere protein H (CENP-H) YabA PF06156.13 KER26118.1 - 1.2 9.9 10.8 0.31 11.7 5.7 2.4 2 0 0 2 2 2 0 Initiation control protein YabA AATF-Che1 PF13339.6 KER26118.1 - 1.6 9.4 11.3 0.44 11.2 7.2 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PilO PF04350.13 KER26118.1 - 2.7 8.1 8.9 1.9 8.7 2.3 3.2 2 1 1 3 3 3 0 Pilus assembly protein, PilO DUF4763 PF15960.5 KER26118.1 - 3.3 7.0 18.3 1.2 8.4 15.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DivIC PF04977.15 KER26118.1 - 4.4 7.1 11.0 7 6.5 7.4 2.7 1 1 1 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.11 KER26118.1 - 4.8 7.0 14.2 46 3.8 10.0 2.9 2 1 0 2 2 2 0 Phage minor structural protein GP20 UPF0242 PF06785.11 KER26118.1 - 6.9 6.7 20.3 0.4 10.8 14.2 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus WBS_methylT PF12589.8 KER26119.1 - 7.5e-12 45.8 4.7 1.1e-11 45.3 4.7 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome APC1_C PF18122.1 KER26119.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF4995 PF16386.5 KER26119.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Methyltransf_11 PF08241.12 KER26119.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_4 PF12763.7 KER26121.1 - 3.1e-12 46.4 0.0 7.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 KER26121.1 - 0.0018 18.1 0.0 0.0076 16.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER26121.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KER26121.1 - 0.083 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Rhabdo_ncap PF00945.18 KER26124.1 - 0.13 11.1 0.7 0.18 10.7 0.7 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 KER26124.1 - 0.14 11.9 3.9 0.17 11.6 3.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KER26124.1 - 0.17 12.3 6.1 0.24 11.8 6.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KER26124.1 - 2 7.7 4.3 2.6 7.3 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein MARVEL PF01284.23 KER26125.1 - 1.7e-06 28.1 20.6 2.9e-06 27.4 20.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain EFhand_Ca_insen PF08726.10 KER26125.1 - 0.0079 16.3 1.8 0.012 15.7 1.8 1.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Cadherin PF00028.17 KER26126.1 - 6.2e-37 125.9 0.0 1.3e-08 35.1 0.0 9.8 8 3 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.12 KER26126.1 - 4.5e-09 36.0 0.0 1.4e-07 31.3 0.0 3.3 3 1 0 3 3 3 1 Cadherin-like Cadherin_3 PF16184.5 KER26126.1 - 0.00012 22.1 2.6 0.14 12.1 0.1 4.4 5 0 0 5 5 5 2 Cadherin-like YqgF PF14639.6 KER26129.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 SAP18 PF06487.12 KER26131.1 - 5.1e-36 123.9 0.0 8.1e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Dynein_light PF01221.18 KER26132.1 - 2.6e-27 94.9 1.1 3.6e-27 94.5 1.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 KER26133.1 - 4.7e-15 55.7 0.0 8.6e-15 54.8 0.0 1.5 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_2 PF07724.14 KER26133.1 - 0.097 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Guanylate_cyc PF00211.20 KER26135.1 - 9.8e-84 279.5 1.8 5.6e-46 156.5 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain NCU-G1 PF15065.6 KER26136.1 - 4.2e-90 302.3 0.0 4.8e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 NCU-G1 PF15065.6 KER26138.1 - 1.5e-19 70.2 1.0 8.7e-17 61.1 0.8 3.1 2 1 0 2 2 2 2 Lysosomal transcription factor, NCU-G1 ABC_tran PF00005.27 KER26139.1 - 3.1e-46 157.3 0.5 1.2e-21 77.7 0.0 3.4 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 KER26139.1 - 1.8e-16 60.8 1.6 0.0026 17.6 0.0 4.7 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER26139.1 - 5.2e-09 35.9 3.9 0.0081 15.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KER26139.1 - 9.7e-07 28.8 0.1 0.0078 16.1 0.0 2.8 2 1 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 KER26139.1 - 1.1e-06 28.5 8.3 1.1e-06 28.5 8.3 3.3 4 0 0 4 4 3 1 ABC transporter AAA_16 PF13191.6 KER26139.1 - 3.6e-06 27.5 0.1 0.16 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KER26139.1 - 5e-06 27.0 0.1 0.044 14.2 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER26139.1 - 6.7e-06 26.4 0.0 0.086 13.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KER26139.1 - 1.2e-05 24.9 0.2 0.035 13.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KER26139.1 - 0.0001 22.3 0.0 0.036 14.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KER26139.1 - 0.00011 22.0 0.0 0.43 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KER26139.1 - 0.00015 21.7 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KER26139.1 - 0.00019 21.7 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KER26139.1 - 0.00021 21.8 2.0 1.8 9.2 0.0 3.9 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 KER26139.1 - 0.00031 21.1 0.0 0.41 11.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KER26139.1 - 0.00057 19.7 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KER26139.1 - 0.00063 19.9 0.0 2.5 8.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KER26139.1 - 0.0024 17.1 0.0 1.1 8.3 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.15 KER26139.1 - 0.0024 17.8 0.1 2.2 8.2 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 KER26139.1 - 0.003 17.6 0.0 2.5 8.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KER26139.1 - 0.0043 17.0 0.1 0.7 9.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KER26139.1 - 0.0072 16.9 0.2 0.22 12.0 0.0 5.5 5 1 0 6 6 3 2 AAA domain cobW PF02492.19 KER26139.1 - 0.0093 15.6 0.0 0.28 10.8 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KER26139.1 - 0.0095 16.2 0.0 5.7 7.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KER26139.1 - 0.015 15.0 13.4 0.12 12.1 0.0 4.4 4 1 1 5 5 3 0 AAA ATPase domain ATPase_2 PF01637.18 KER26139.1 - 0.028 14.3 0.2 3.2 7.6 0.0 3.1 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KER26139.1 - 0.038 13.5 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 KER26139.1 - 0.049 13.3 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KER26139.1 - 0.12 12.4 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Imm3 PF14425.6 KER26139.1 - 0.37 10.8 2.2 1.4 9.0 0.2 2.5 2 0 0 2 2 2 0 Immunity protein Imm3 Dynamin_N PF00350.23 KER26139.1 - 4 7.5 9.2 9.6 6.2 0.0 4.2 5 0 0 5 5 5 0 Dynamin family CENP-F_leu_zip PF10473.9 KER26140.1 - 0.0083 16.1 10.4 0.0083 16.1 10.4 6.8 2 2 5 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 kleA_kleC PF17383.2 KER26140.1 - 0.013 15.8 3.2 0.013 15.8 3.2 7.1 7 2 0 7 7 7 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 KER26140.1 - 0.027 13.4 94.4 0.18 10.7 12.9 5.9 2 1 5 7 7 7 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KER26140.1 - 0.095 12.7 38.6 0.15 12.1 0.1 6.0 2 1 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 KER26142.1 - 0.0018 18.4 22.7 0.0018 18.4 22.7 3.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KER26142.1 - 0.0061 16.6 6.7 0.0061 16.6 6.7 4.9 2 1 2 5 5 5 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 KER26142.1 - 0.0063 16.8 83.8 0.042 14.1 17.6 5.0 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) Polysacc_syn_2C PF08485.10 KER26142.1 - 0.07 12.8 1.1 0.28 10.9 0.1 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal HMMR_N PF15905.5 KER26142.1 - 0.21 11.1 62.2 4.1 6.8 0.3 3.8 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 KER26142.1 - 0.29 11.6 78.7 0.036 14.6 26.6 4.4 2 1 3 5 5 5 0 Apg6 coiled-coil region Spc7 PF08317.11 KER26142.1 - 0.38 9.6 69.3 0.029 13.3 20.7 4.5 2 1 3 5 5 5 0 Spc7 kinetochore protein SKA1 PF07160.12 KER26142.1 - 0.55 10.0 47.9 0.033 14.1 13.7 4.3 2 1 2 4 4 4 0 Spindle and kinetochore-associated protein 1 DUF812 PF05667.11 KER26142.1 - 1.1 8.0 59.4 0.31 9.9 22.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 KER26142.1 - 1.3 9.4 63.0 0.37 11.1 2.9 4.9 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 KER26142.1 - 1.3 9.4 67.5 0.19 12.1 19.8 5.3 2 1 2 5 5 5 0 Domain of unknown function (DUF4200) Fez1 PF06818.15 KER26142.1 - 1.8 9.0 61.9 0.83 10.1 28.5 3.6 2 1 2 4 4 4 0 Fez1 FliJ PF02050.16 KER26142.1 - 3.4 7.9 72.9 0.3 11.3 13.4 5.2 2 1 3 5 5 5 0 Flagellar FliJ protein WEMBL PF05701.11 KER26142.1 - 8 5.0 58.4 0.77 8.4 31.4 3.1 2 1 1 3 3 3 0 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.9 KER26142.1 - 9.1 6.3 69.4 0.042 13.9 17.4 4.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRR_4 PF12799.7 KER26143.1 - 6.1e-06 26.5 3.4 7.7e-05 23.0 2.9 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER26143.1 - 0.00012 21.8 4.3 0.0004 20.1 3.9 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 KER26143.1 - 0.0002 20.9 0.2 0.00036 20.1 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat ATG16 PF08614.11 KER26143.1 - 0.0053 17.0 9.0 0.0053 17.0 9.0 3.1 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) Med9 PF07544.13 KER26143.1 - 0.048 13.7 1.1 5.3 7.2 0.9 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LRR_6 PF13516.6 KER26143.1 - 0.73 10.0 3.9 13 6.2 0.4 2.8 2 0 0 2 2 2 0 Leucine Rich repeat DUF3552 PF12072.8 KER26143.1 - 4.8 6.6 10.6 8.2 5.8 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-C2H2 PF00096.26 KER26145.1 - 1.1e-25 88.5 37.3 3.9e-07 30.2 1.1 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER26145.1 - 5.6e-18 64.1 34.7 0.00011 22.8 0.8 6.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER26145.1 - 8.4e-14 51.3 49.3 1.2e-08 35.0 0.7 7.8 8 0 0 8 8 7 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER26145.1 - 7.7e-08 32.4 13.5 1.2 9.5 0.0 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KER26145.1 - 2.4e-06 27.7 27.4 0.00086 19.6 3.2 4.4 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KER26145.1 - 4.4e-06 26.6 27.3 0.0012 18.8 0.2 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER26145.1 - 0.04 13.7 0.4 0.04 13.7 0.4 5.8 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-WRNIP1_ubi PF18279.1 KER26145.1 - 0.18 12.5 3.8 22 6.0 0.1 3.4 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-met PF12874.7 KER26145.1 - 0.19 12.1 22.2 0.65 10.5 0.3 5.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type UBZ_FAAP20 PF15750.5 KER26145.1 - 0.23 11.4 4.9 0.76 9.8 0.3 3.6 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-C2H2_2 PF12756.7 KER26145.1 - 0.88 9.9 31.5 1 9.8 1.3 5.4 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KER26145.1 - 0.95 9.5 32.4 0.66 10.1 0.9 4.9 3 2 2 5 5 5 0 BED zinc finger zf_UBZ PF18439.1 KER26145.1 - 2.4 7.8 14.4 7.5 6.2 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 KER26145.1 - 4.2 7.9 13.3 1.8 9.1 3.1 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 KER26145.1 - 6.4 7.6 19.0 7.5 7.4 5.6 3.3 2 1 1 3 3 3 0 zinc-ribbon family DUF2256 PF10013.9 KER26145.1 - 9.2 6.5 15.4 6.6 6.9 0.2 5.3 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) LIM PF00412.22 KER26148.1 - 1.3e-26 92.6 4.3 2.3e-12 47.0 0.3 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KER26148.1 - 6.9e-18 64.2 2.2 1.3e-17 63.4 2.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER26148.1 - 0.0045 16.8 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain DZR PF12773.7 KER26148.1 - 0.0055 16.7 4.9 3.1 7.9 0.8 3.1 1 1 1 2 2 2 2 Double zinc ribbon Gamma-thionin PF00304.20 KER26148.1 - 0.032 14.5 7.4 2.2 8.6 0.4 3.1 3 0 0 3 3 3 0 Gamma-thionin family Homez PF11569.8 KER26148.1 - 0.072 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF2175 PF09943.9 KER26148.1 - 0.11 12.8 0.8 20 5.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TNFR_c6 PF00020.18 KER26148.1 - 0.15 12.5 5.0 12 6.4 0.4 3.1 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region DUF1272 PF06906.11 KER26148.1 - 0.23 11.6 3.2 18 5.5 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Fer4_4 PF12800.7 KER26148.1 - 0.38 11.4 9.1 26 5.7 0.8 4.2 3 0 0 3 3 3 0 4Fe-4S binding domain zf-RING_10 PF16685.5 KER26148.1 - 2.7 8.2 7.4 20 5.4 0.9 2.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc_ribbon_10 PF10058.9 KER26148.1 - 3.8 7.3 13.6 10 5.9 3.0 2.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein NAP PF00956.18 KER26151.1 - 1e-35 123.2 23.2 8.3e-31 107.1 15.1 3.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) NOA36 PF06524.12 KER26151.1 - 0.12 11.7 6.3 0.2 11.0 6.3 1.4 1 0 0 1 1 1 0 NOA36 protein Sec20 PF03908.13 KER26151.1 - 0.16 11.9 0.1 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Sec20 MYT1 PF08474.11 KER26151.1 - 0.39 10.6 3.3 0.6 10.0 3.3 1.4 1 0 0 1 1 1 0 Myelin transcription factor 1 Astro_capsid_p PF12226.8 KER26151.1 - 6.9 5.7 8.4 11 5.1 8.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PAN_1 PF00024.26 KER26153.1 - 0.0027 17.6 0.9 0.0027 17.6 0.9 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 KER26153.1 - 0.063 13.2 2.0 0.21 11.6 2.0 1.8 1 0 0 1 1 1 0 PAN domain zf-C2H2 PF00096.26 KER26157.1 - 9.6e-17 60.4 44.2 2.5e-05 24.5 1.2 6.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER26157.1 - 2.8e-11 43.2 45.5 0.0016 19.1 1.1 6.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER26157.1 - 1.1e-05 25.6 52.1 0.00046 20.5 0.5 6.9 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER26157.1 - 0.00027 20.8 38.6 0.029 14.4 0.2 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger zf_UBZ PF18439.1 KER26157.1 - 0.013 15.0 19.4 2.5 7.8 0.2 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KER26157.1 - 0.15 12.4 32.2 0.14 12.4 0.8 5.8 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KER26157.1 - 0.17 11.7 0.2 0.17 11.7 0.2 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type DUF629 PF04780.12 KER26157.1 - 0.28 9.7 0.0 0.28 9.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 KER26157.1 - 0.89 9.5 17.0 1.5 8.7 0.2 4.9 3 3 3 6 6 6 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 KER26157.1 - 0.98 9.7 14.3 3.3 8.0 0.2 4.7 3 1 0 3 3 3 0 zinc-ribbon ROS_MUCR PF05443.11 KER26157.1 - 1.1 9.4 5.8 4 7.5 0.4 2.8 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein zf-C2H2_8 PF15909.5 KER26157.1 - 3.5 8.0 25.5 0.04 14.2 6.9 3.7 2 1 2 4 4 4 0 C2H2-type zinc ribbon Terminase_GpA PF05876.12 KER26157.1 - 3.8 6.0 15.0 0.3 9.6 4.8 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Zn-ribbon_8 PF09723.10 KER26157.1 - 9.7 6.4 26.8 0.85 9.8 1.0 5.1 3 2 1 4 4 4 0 Zinc ribbon domain BACK PF07707.15 KER26159.1 - 7.8e-25 87.0 0.2 1.4e-24 86.1 0.2 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 KER26159.1 - 9.2e-22 76.4 4.9 1e-09 37.8 0.2 3.4 3 0 0 3 3 3 3 Kelch motif BTB PF00651.31 KER26159.1 - 1.8e-20 73.3 1.0 6.8e-16 58.5 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain Kelch_6 PF13964.6 KER26159.1 - 5.5e-11 42.4 5.6 7.6e-06 26.0 0.1 3.5 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KER26159.1 - 8.3e-11 41.7 0.3 1.8e-06 27.8 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KER26159.1 - 2.7e-07 30.3 2.7 0.0074 16.2 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KER26159.1 - 0.00087 19.5 0.8 0.28 11.5 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain YesK PF14150.6 KER26159.1 - 0.038 14.2 0.3 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 YesK-like protein Kelch_5 PF13854.6 KER26159.1 - 0.84 9.7 8.2 1.2 9.2 0.1 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 KER26161.1 - 7.8e-16 57.4 0.0 5.1e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KER26161.1 - 2.3e-05 24.3 0.0 0.00092 19.2 0.0 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KER26161.1 - 6.6e-05 23.0 0.1 0.32 11.4 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 KER26161.1 - 0.0017 18.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KER26161.1 - 0.002 18.4 0.1 1.1 9.7 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain zf_CCCH_4 PF18345.1 KER26163.1 - 4.1e-08 33.0 3.4 6.3e-08 32.4 3.4 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KER26163.1 - 6.6e-07 29.1 2.2 1.2e-06 28.3 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER26163.1 - 1.2e-06 28.1 1.0 1.9e-06 27.5 1.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KER26163.1 - 0.0022 18.7 0.4 0.0033 18.1 0.4 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KER26163.1 - 0.077 13.5 2.0 0.13 12.7 2.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger TMF_DNA_bd PF12329.8 KER26166.1 - 0.053 13.5 0.7 0.053 13.5 0.7 7.4 3 1 6 9 9 9 0 TATA element modulatory factor 1 DNA binding DUF452 PF04301.13 KER26166.1 - 0.091 12.3 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF452) DUF2935 PF11155.8 KER26166.1 - 2 8.8 19.7 1.9 8.8 4.0 4.3 1 1 1 3 3 3 0 Domain of unknown function (DUF2935) APG6_N PF17675.1 KER26166.1 - 2.8 8.4 67.6 7.3 7.1 9.5 5.2 2 1 2 4 4 4 0 Apg6 coiled-coil region Filament PF00038.21 KER26166.1 - 4.6 6.7 58.7 2 7.9 15.4 3.3 1 1 1 3 3 3 0 Intermediate filament protein Nucleoporin_FG2 PF15967.5 KER26166.1 - 6.7 5.1 5.0 11 4.4 5.0 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region Acyl-CoA_dh_1 PF00441.24 KER26167.1 - 4.2e-55 186.1 13.7 5.1e-39 133.9 3.6 3.2 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KER26167.1 - 6.7e-27 93.5 0.1 1.4e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KER26167.1 - 4.4e-22 78.9 0.0 1.9e-21 76.8 0.0 2.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KER26167.1 - 7.7e-20 71.5 10.2 1.3e-14 54.6 2.2 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain 7tm_6 PF02949.20 KER26167.1 - 0.0029 16.8 2.9 1.9 7.5 0.0 3.2 4 0 0 4 4 4 2 7tm Odorant receptor Surp PF01805.20 KER26167.1 - 0.036 14.1 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Surp module Syntaxin_2 PF14523.6 KER26167.1 - 0.055 13.8 5.8 3.6 8.0 0.3 2.8 3 0 0 3 3 3 0 Syntaxin-like protein MHB PF16525.5 KER26167.1 - 0.093 13.0 6.2 2.8 8.3 0.6 2.7 2 0 0 2 2 2 0 Haemophore, haem-binding PRODH PF18327.1 KER26167.1 - 0.3 11.3 4.4 12 6.2 0.4 2.6 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain CysG_dimeriser PF10414.9 KER26167.1 - 1.1 9.0 6.4 11 5.8 0.3 2.9 4 0 0 4 4 4 0 Sirohaem synthase dimerisation region EIF4E-T PF10477.9 KER26171.1 - 2.2e-07 30.1 3.1 2.9e-07 29.7 3.1 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RVT_1 PF00078.27 KER26172.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ARL17 PF15840.5 KER26173.1 - 0.11 12.9 1.8 0.14 12.6 0.4 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor-like protein 17 tRNA-synt_1c PF00749.21 KER26175.1 - 2.7e-106 355.0 0.0 3.4e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KER26175.1 - 6.9e-42 143.3 0.0 1.6e-41 142.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KER26175.1 - 2e-09 38.2 0.0 3.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 RVT_1 PF00078.27 KER26176.1 - 1.8e-07 30.9 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_7 PF13499.6 KER26178.1 - 4.1e-19 68.8 1.9 1.4e-15 57.5 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER26178.1 - 6.2e-15 53.6 8.0 5.3e-09 35.0 0.8 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KER26178.1 - 4.5e-14 52.0 8.2 8.4e-12 44.8 0.2 3.3 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KER26178.1 - 3.2e-11 42.2 7.2 4.3e-05 23.1 0.2 3.6 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KER26178.1 - 6.7e-08 31.7 6.7 2.6e-05 23.5 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KER26178.1 - 1.9e-05 24.9 0.1 8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KER26178.1 - 0.01 15.8 1.4 0.22 11.5 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ICAT PF06384.11 KER26178.1 - 0.038 14.2 0.3 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT FGAR-AT_linker PF18072.1 KER26178.1 - 0.05 14.2 0.8 23 5.6 0.1 3.1 2 2 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF5126 PF17166.4 KER26178.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) VEGFR-2_TMD PF17988.1 KER26181.1 - 0.027 13.9 0.2 0.045 13.2 0.2 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DEAD PF00270.29 KER26183.1 - 4.2e-18 65.7 0.0 1e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER26183.1 - 1.6e-16 60.6 0.0 2.6e-15 56.7 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER26183.1 - 7.6e-15 55.3 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER26183.1 - 0.037 14.3 0.0 0.38 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 KER26184.1 - 3.3e-44 148.7 5.3 6.8e-17 61.2 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KER26185.1 - 7.3e-20 71.2 40.2 2.5e-17 62.8 17.5 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily zf-C2HC PF01530.18 KER26186.1 - 0.09 13.0 1.1 0.21 11.8 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2HC type ASH PF15780.5 KER26187.1 - 4.9e-30 103.6 12.3 0.00017 21.7 0.1 10.4 10 0 0 10 10 10 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 KER26187.1 - 1.6e-06 28.2 0.7 0.042 14.0 0.0 5.5 5 1 1 6 6 6 1 Flagellar-associated PapD-like DUF1573 PF07610.11 KER26187.1 - 8.4e-05 22.5 0.3 2.7 8.1 0.0 5.8 6 0 0 6 6 6 1 Protein of unknown function (DUF1573) PapD_N PF00345.20 KER26187.1 - 0.042 13.7 3.6 0.17 11.8 0.0 3.6 4 0 0 4 4 4 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4503 PF14951.6 KER26193.1 - 7.4e-05 21.4 2.0 0.00013 20.6 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) NDUF_B4 PF07225.12 KER26195.1 - 1.7e-14 53.8 0.0 2.1e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Carn_acyltransf PF00755.20 KER26196.1 - 1.8e-142 476.0 0.0 2e-142 475.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 KER26197.1 - 5e-36 124.5 0.0 6e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KER26198.1 - 7.9e-34 117.1 37.9 3.5e-31 108.4 29.1 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 KER26198.1 - 0.0012 17.7 4.3 0.0012 17.7 4.3 2.3 3 0 0 3 3 3 1 LacY proton/sugar symporter MFS_1_like PF12832.7 KER26198.1 - 8.5 5.1 19.6 0.28 10.0 5.7 2.2 1 1 1 2 2 2 0 MFS_1 like family Cpn60_TCP1 PF00118.24 KER26200.1 - 3.5e-39 134.8 0.4 3.9e-39 134.6 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2802 PF10975.8 KER26200.1 - 0.07 13.3 0.3 0.17 12.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) Cpn60_TCP1 PF00118.24 KER26201.1 - 8.1e-06 24.7 0.2 1.1e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 KER26202.1 - 2.8e-92 309.9 4.3 9.1e-86 288.4 2.7 2.1 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3395 PF11875.8 KER26202.1 - 2e-37 128.5 0.0 3.7e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KER26202.1 - 4e-17 62.1 0.0 1.2e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 KER26202.1 - 0.0071 16.9 0.1 7.3 7.2 0.0 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I HAMP PF00672.25 KER26203.1 - 0.081 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 HAMP domain EF-hand_1 PF00036.32 KER26204.1 - 2.9e-27 92.1 13.8 3.9e-07 29.1 0.6 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER26204.1 - 3.1e-24 85.2 3.9 4.9e-13 49.3 1.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER26204.1 - 1.5e-22 77.5 6.8 3.6e-05 23.4 0.4 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER26204.1 - 9.8e-21 72.3 9.6 2.3e-05 23.7 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KER26204.1 - 1.5e-13 50.3 15.5 0.00053 19.8 0.2 5.2 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER26204.1 - 1.5e-07 31.7 0.8 0.01 16.2 0.1 3.1 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER26204.1 - 2.4e-06 27.4 3.3 0.015 15.2 0.8 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KER26204.1 - 0.0024 18.2 0.4 0.21 11.9 0.1 2.9 2 2 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 KER26204.1 - 0.2 11.9 3.5 9.9 6.4 1.0 3.7 3 1 1 4 4 4 0 Dockerin type I domain zf-C2H2 PF00096.26 KER26206.1 - 9.5e-16 57.3 46.1 0.00026 21.3 1.0 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KER26206.1 - 1.3e-11 44.0 22.9 4.2e-10 39.2 0.4 5.7 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KER26206.1 - 2.4e-08 34.0 42.3 0.00025 21.3 2.7 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER26206.1 - 1.1e-06 29.0 51.5 0.063 14.1 0.3 8.3 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2HE PF16278.5 KER26206.1 - 3.2e-05 24.3 14.5 0.00011 22.5 0.1 4.0 3 2 1 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 KER26206.1 - 0.16 12.1 5.1 1.1 9.3 2.8 2.6 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KER26206.1 - 0.3 11.4 19.0 1.9 8.9 0.5 5.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER26206.1 - 1.2 9.6 23.2 0.7 10.4 1.3 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.6 KER26206.1 - 1.7 8.6 10.0 9.1 6.3 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain PriA_CRR PF18319.1 KER26206.1 - 2.6 8.1 13.5 21 5.2 1.8 4.3 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain Ephrin_rec_like PF07699.13 KER26207.1 - 7.1e-08 32.1 4.8 7.1e-08 32.1 4.8 3.0 3 0 0 3 3 3 1 Putative ephrin-receptor like NCD3G PF07562.14 KER26207.1 - 0.015 15.2 3.9 0.052 13.5 0.4 2.8 2 1 2 4 4 4 0 Nine Cysteines Domain of family 3 GPCR Tubulin PF00091.25 KER26208.1 - 7.6e-53 179.6 0.1 2.3e-51 174.8 0.1 2.2 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER26208.1 - 6.2e-29 100.7 0.3 1.4e-28 99.6 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain DUF276 PF03434.13 KER26208.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 DUF276 SNF PF00209.18 KER26209.1 - 8.5e-40 136.9 15.7 1e-39 136.6 15.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.18 KER26210.1 - 1e-47 163.0 8.4 1.1e-47 162.9 8.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family MerC PF03203.14 KER26210.1 - 0.51 10.8 8.9 0.088 13.3 1.3 2.5 1 1 1 3 3 3 0 MerC mercury resistance protein SNF PF00209.18 KER26211.1 - 2e-05 23.5 3.1 2.1e-05 23.4 3.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family LMBR1 PF04791.16 KER26211.1 - 0.013 14.5 1.5 0.015 14.2 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BCHF PF07284.11 KER26211.1 - 0.04 13.9 0.7 0.054 13.5 0.7 1.2 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) MpPF26 PF07666.11 KER26211.1 - 0.097 12.8 3.5 0.13 12.3 3.5 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 7tm_1 PF00001.21 KER26212.1 - 5.4e-47 160.3 19.0 5.4e-47 160.3 19.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER26212.1 - 2.4e-14 53.4 19.0 5.1e-09 35.9 9.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 KER26212.1 - 4e-14 52.6 14.1 8.1e-14 51.6 14.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KER26212.1 - 1.3e-10 41.1 21.1 6.3e-09 35.6 21.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.9 KER26212.1 - 7.7e-10 38.8 20.1 2.8e-09 37.0 20.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 KER26212.1 - 8.6e-05 22.4 5.1 8.6e-05 22.4 5.1 1.5 2 0 0 2 2 2 1 Olfactory receptor Pkinase_Tyr PF07714.17 KER26215.1 - 1.1e-75 254.3 0.1 2.8e-70 236.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER26215.1 - 5.3e-44 150.6 0.0 7.3e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER26215.1 - 2e-11 43.8 0.0 5.5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 KER26215.1 - 6.2e-05 22.4 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH2_2 PF14633.6 KER26215.1 - 0.00019 20.9 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KER26215.1 - 0.00027 20.0 0.1 0.00078 18.5 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain SNF PF00209.18 KER26216.1 - 2e-175 584.4 38.1 2.3e-175 584.2 38.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PH_TFIIH PF08567.11 KER26218.1 - 1.8e-21 76.2 0.1 3.5e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KER26218.1 - 4.3e-18 65.1 0.9 1.7e-13 50.3 0.2 2.5 2 0 0 2 2 2 2 BSD domain Lipase_3 PF01764.25 KER26219.1 - 6.2e-11 42.3 0.0 9.1e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 KER26219.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_C42 PF05533.12 KER26219.1 - 0.024 14.7 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 Abhydrolase_3 PF07859.13 KER26219.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PARP PF00644.20 KER26221.1 - 1.8e-16 60.4 0.0 1.9e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HLH PF00010.26 KER26222.1 - 3.2e-14 52.6 0.6 5.2e-14 51.9 0.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PARP_reg PF02877.14 KER26223.1 - 1.1e-28 100.1 0.1 2.1e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KER26223.1 - 4.1e-27 94.0 1.0 9.1e-27 93.0 1.0 1.6 1 0 0 1 1 1 1 WGR domain DUF1623 PF07785.11 KER26223.1 - 0.00023 21.3 1.4 0.00078 19.6 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1623) DUF3910 PF13049.6 KER26223.1 - 0.045 14.0 0.1 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) IQCJ-SCHIP1 PF15157.6 KER26224.1 - 0.55 10.1 4.3 10 6.0 0.4 2.3 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif UQ_con PF00179.26 KER26226.1 - 8.5e-17 61.1 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KER26226.1 - 0.19 12.0 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain zf-C3HC4_2 PF13923.6 KER26228.1 - 4.8e-12 45.5 8.1 3.6e-11 42.7 7.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER26228.1 - 1.4e-10 41.4 7.4 3.8e-10 39.9 6.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KER26228.1 - 2.1e-09 37.3 11.0 5e-09 36.0 10.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER26228.1 - 2.1e-09 37.1 9.3 2.3e-09 37.0 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER26228.1 - 8.9e-08 31.9 4.1 1.8e-07 30.9 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KER26228.1 - 4.1e-06 26.8 7.9 4.1e-06 26.8 7.9 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KER26228.1 - 1.3e-05 25.4 11.1 5.3e-05 23.4 8.7 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 KER26228.1 - 1.3e-05 25.3 0.8 2.7e-05 24.3 0.1 1.9 2 1 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.6 KER26228.1 - 5.6e-05 22.9 9.7 0.00095 19.0 9.4 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KER26228.1 - 0.00021 21.2 5.5 0.00082 19.3 5.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 KER26228.1 - 0.016 15.4 3.4 0.034 14.3 3.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Parathyroid PF01279.17 KER26228.1 - 0.027 15.1 0.1 0.027 15.1 0.1 1.5 2 0 0 2 2 1 0 Parathyroid hormone family zf-RING_11 PF17123.5 KER26228.1 - 0.19 11.5 6.4 1.1 9.1 5.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 KER26228.1 - 0.25 11.2 10.5 1.5 8.7 8.3 2.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 KER26228.1 - 1.8 8.5 6.8 9 6.3 6.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 KER26229.1 - 6.7e-26 91.0 0.0 1.4e-25 89.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER26229.1 - 9.1e-19 67.9 0.0 2e-18 66.8 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER26229.1 - 0.0045 16.9 0.2 0.0075 16.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Peptidase_M27 PF01742.17 KER26229.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Glypican PF01153.19 KER26231.1 - 1.3e-31 110.1 4.7 1e-21 77.4 0.0 2.3 2 0 0 2 2 2 2 Glypican DUF1474 PF07342.11 KER26231.1 - 0.78 10.3 2.6 0.39 11.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) N_Asn_amidohyd PF14736.6 KER26232.1 - 2.3e-36 125.3 0.0 4.1e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase INT_SG_DDX_CT_C PF15300.6 KER26232.1 - 2.5e-16 59.2 0.0 5.9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA_2 PF13519.6 KER26232.1 - 3.2e-12 47.1 0.0 8.3e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KER26232.1 - 0.0034 17.6 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain OB_NTP_bind PF07717.16 KER26233.1 - 1.9e-11 44.2 0.0 6.2e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KER26233.1 - 2.3e-11 44.0 0.0 5.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KER26233.1 - 1.8e-08 34.6 0.1 6.5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KER26233.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KER26233.1 - 0.00018 21.8 0.0 0.00046 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KER26233.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KER26233.1 - 0.034 13.2 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.9 KER26233.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 KER26233.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 KER26233.1 - 0.25 11.8 0.0 0.44 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4541 PF15074.6 KER26237.1 - 2.3e-34 117.8 0.1 3.1e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) UPF0020 PF01170.18 KER26238.1 - 1.3e-05 24.9 0.1 0.0082 15.8 0.1 2.6 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KER26238.1 - 0.026 14.2 0.0 1.6 8.3 0.0 2.7 2 1 0 2 2 2 0 DNA methylase SepSecS PF05889.13 KER26239.1 - 4.2e-56 190.3 0.0 3.2e-34 118.3 0.0 2.1 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MAM PF00629.23 KER26243.1 - 3.2e-05 23.9 0.0 0.00042 20.3 0.0 2.3 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Adeno_E3_CR2 PF02439.15 KER26243.1 - 0.002 17.8 1.5 0.0026 17.5 0.2 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 MAM PF00629.23 KER26245.1 - 8.7e-09 35.5 4.3 1.2e-05 25.3 0.1 2.5 2 1 0 2 2 2 2 MAM domain, meprin/A5/mu MAM PF00629.23 KER26247.1 - 0.00079 19.4 0.6 0.0039 17.1 0.6 1.9 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KER26249.1 - 0.0046 16.9 1.2 0.069 13.1 1.2 2.1 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu MAM PF00629.23 KER26251.1 - 5.5e-08 32.9 18.6 0.0014 18.6 0.9 5.4 3 3 0 3 3 3 3 MAM domain, meprin/A5/mu P5CR_dimer PF14748.6 KER26253.1 - 1.6e-37 127.8 1.0 1.6e-37 127.8 1.0 2.4 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KER26253.1 - 1.5e-16 60.8 0.5 7e-16 58.6 0.5 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KER26253.1 - 0.01 14.9 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KER26253.1 - 0.032 14.4 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RhoGAP PF00620.27 KER26254.1 - 1.2e-41 142.1 0.0 1.8e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KER26254.1 - 3.8e-14 52.3 4.6 6.4e-14 51.6 4.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KER26254.1 - 0.068 13.5 3.3 0.18 12.2 3.3 1.7 1 0 0 1 1 1 0 C1 domain zf-RING-like PF08746.11 KER26254.1 - 0.29 11.5 3.9 0.58 10.5 3.9 1.5 1 0 0 1 1 1 0 RING-like domain RHINO PF15319.6 KER26255.1 - 0.036 14.1 5.4 0.079 13.0 1.0 2.3 1 1 1 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Flo11 PF10182.9 KER26257.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Flo11 domain Gelsolin PF00626.22 KER26258.1 - 6.3e-17 61.3 0.5 0.0012 18.7 0.0 5.7 6 0 0 6 6 6 3 Gelsolin repeat VHP PF02209.19 KER26258.1 - 1.6e-16 60.1 1.1 3.4e-16 59.0 1.1 1.6 1 0 0 1 1 1 1 Villin headpiece domain RHH_7 PF16777.5 KER26258.1 - 0.093 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Pkinase PF00069.25 KER26260.1 - 3.5e-59 200.3 0.0 5.1e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26260.1 - 2.6e-36 125.3 0.0 4.2e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KER26260.1 - 2e-10 40.6 11.9 2e-09 37.4 3.6 2.9 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 KER26260.1 - 4.7e-07 30.4 2.8 1.4e-06 28.9 2.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KER26260.1 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Uds1 PF15456.6 KER26260.1 - 0.00043 20.5 4.0 0.21 11.7 0.3 3.0 2 0 0 2 2 2 2 Up-regulated During Septation DUF309 PF03745.14 KER26261.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Choline_transpo PF04515.12 KER26264.1 - 1.3e-97 326.9 23.1 1.3e-97 326.9 23.1 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter DEAD PF00270.29 KER26266.1 - 2.1e-49 167.6 0.1 6.6e-49 166.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER26266.1 - 1.2e-21 77.2 0.0 7.2e-21 74.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KER26266.1 - 1.4e-16 60.5 3.4 3.9e-16 59.1 3.4 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DUF1247 PF06851.11 KER26266.1 - 0.17 11.8 0.1 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) AKAP28 PF14469.6 KER26267.1 - 1.6e-49 166.7 0.1 3.1e-49 165.8 0.1 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor KIAA1430 PF13879.6 KER26267.1 - 3.3e-13 50.3 5.6 5.9e-13 49.5 5.6 1.4 1 0 0 1 1 1 1 KIAA1430 homologue Herpes_BLRF2 PF05812.12 KER26267.1 - 0.068 13.3 2.1 0.38 10.9 0.6 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Y_phosphatase PF00102.27 KER26268.1 - 7.6e-67 225.3 0.0 1.1e-65 221.5 0.0 2.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 KER26268.1 - 3.1e-48 161.8 0.2 2.4e-23 82.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.20 KER26268.1 - 0.00021 21.1 0.1 0.00044 20.1 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KER26268.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KER26268.1 - 0.05 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family tRNA_bind PF01588.20 KER26270.1 - 1.1e-28 99.2 0.1 1.8e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain HALZ PF02183.18 KER26270.1 - 0.018 15.2 2.2 0.018 15.2 0.5 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper ThiF PF00899.21 KER26271.1 - 5.1e-62 209.4 0.0 6.9e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family DAO PF01266.24 KER26271.1 - 0.03 13.9 0.4 0.075 12.6 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 KER26271.1 - 0.042 13.5 0.5 0.13 11.9 0.5 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KER26271.1 - 0.065 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KER26271.1 - 0.17 11.1 0.2 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KER26271.1 - 5.3 6.3 5.3 15 4.8 0.2 2.6 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Longin PF13774.6 KER26272.1 - 2e-19 69.4 0.1 4.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KER26272.1 - 3.1e-17 62.1 1.7 6.1e-17 61.2 0.7 1.8 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 KER26272.1 - 0.0021 17.9 0.3 0.0048 16.8 0.3 1.6 1 0 0 1 1 1 1 Sec20 Pox_EPC_I2-L1 PF12575.8 KER26272.1 - 0.089 13.0 3.1 0.17 12.1 0.6 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Amnionless PF14828.6 KER26272.1 - 0.097 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Vma12 PF11712.8 KER26272.1 - 0.18 11.9 1.2 0.36 10.9 1.2 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RRM_1 PF00076.22 KER26273.1 - 7.2e-19 67.4 0.0 1.6e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER26273.1 - 0.16 11.9 0.0 3.8 7.5 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_L11_N PF03946.14 KER26275.1 - 1.6e-24 85.5 0.0 3.1e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KER26275.1 - 5.9e-18 65.1 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Med27 PF11571.8 KER26277.1 - 9.1e-23 80.4 0.1 3e-22 78.8 0.1 1.9 1 0 0 1 1 1 1 Mediator complex subunit 27 FCH PF00611.23 KER26279.1 - 6e-17 61.7 0.1 2.2e-16 59.9 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KER26279.1 - 3.1e-12 46.2 1.7 8.5e-07 28.7 0.0 4.1 3 1 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KER26279.1 - 1.3e-10 40.7 0.0 0.0019 17.7 0.0 4.4 4 0 0 4 4 4 2 SH3 domain SH3_2 PF07653.17 KER26279.1 - 9e-05 22.1 0.0 0.13 12.0 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain DUF4709 PF15821.5 KER26279.1 - 0.57 10.5 3.6 19 5.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) DUF2937 PF11157.8 KER26279.1 - 1.9 8.2 5.8 4.3 7.0 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2937) GDPD PF03009.17 KER26280.1 - 7.1e-25 88.2 0.0 5.3e-23 82.1 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyco_transf_64 PF09258.10 KER26281.1 - 4.4e-64 216.1 0.0 3.5e-63 213.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain PTPA PF03095.15 KER26281.1 - 0.14 11.6 0.1 3.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.7 KER26282.1 - 9.4e-12 45.4 0.1 2.9e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KER26282.1 - 2.1e-11 43.8 3.7 0.03 14.8 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KER26282.1 - 5.9e-10 39.5 2.8 5.1e-05 23.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER26282.1 - 3.6e-05 24.0 2.3 0.00024 21.3 1.3 2.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER26282.1 - 0.00096 19.4 3.4 12 6.9 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat mRNA_cap_enzyme PF01331.19 KER26283.1 - 4.3e-43 147.4 0.0 3.6e-42 144.4 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DSPc PF00782.20 KER26283.1 - 3.4e-13 49.5 0.0 5.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER26283.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DNA_ligase_A_M PF01068.21 KER26283.1 - 0.0019 17.9 0.0 0.0064 16.2 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PTPlike_phytase PF14566.6 KER26283.1 - 0.0031 17.7 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 KER26283.1 - 0.052 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KER26283.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family NinE PF05322.11 KER26283.1 - 0.18 11.7 0.1 0.43 10.5 0.1 1.6 1 0 0 1 1 1 0 NINE Protein WH2 PF02205.20 KER26286.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 WH2 motif 53-BP1_Tudor PF09038.10 KER26289.1 - 2.5e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor LBR_tudor PF09465.10 KER26289.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TSC22 PF01166.18 KER26290.1 - 0.00018 21.7 0.9 0.00026 21.2 0.9 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family MAD PF05557.13 KER26290.1 - 0.002 16.6 0.3 0.002 16.6 0.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein K-box PF01486.17 KER26290.1 - 0.008 16.3 0.3 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 K-box region bZIP_1 PF00170.21 KER26290.1 - 0.0094 16.0 1.6 0.019 15.0 1.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KER26290.1 - 0.012 16.2 1.6 0.02 15.5 1.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KER26290.1 - 0.013 15.3 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KER26290.1 - 0.031 14.7 2.3 0.053 14.0 2.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB RNA_pol_Rpb2_2 PF04561.14 KER26290.1 - 0.045 13.4 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Herpes_BLRF2 PF05812.12 KER26290.1 - 0.046 13.9 1.1 0.075 13.2 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein MCC-bdg_PDZ PF10506.9 KER26290.1 - 0.064 13.3 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TolA_bind_tri PF16331.5 KER26290.1 - 0.072 13.2 1.2 0.12 12.5 1.2 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation APC_N_CC PF16689.5 KER26290.1 - 0.16 12.1 2.8 0.28 11.3 1.7 1.9 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain UPF0449 PF15136.6 KER26290.1 - 0.17 12.4 2.6 0.18 12.3 1.3 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Galactosyl_T PF01762.21 KER26291.1 - 3.1e-38 131.6 0.0 6e-38 130.6 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Fringe PF02434.16 KER26291.1 - 0.00043 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 Fringe-like zf-C2H2 PF00096.26 KER26293.1 - 1.5e-12 47.2 26.5 0.00029 21.1 1.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER26293.1 - 1.5e-10 41.0 8.3 4.4e-07 30.0 0.7 3.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER26293.1 - 1.3e-06 28.7 20.4 0.15 13.0 1.1 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KER26293.1 - 0.15 12.2 2.9 0.94 9.6 2.5 2.3 1 1 0 1 1 1 0 Aberrant zinc-finger Ogr_Delta PF04606.12 KER26293.1 - 0.29 11.1 3.1 0.3 11.1 0.4 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 KER26293.1 - 9.8 6.6 7.2 5.8 7.3 1.8 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RVT_1 PF00078.27 KER26294.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Galactosyl_T PF01762.21 KER26295.1 - 3.5e-44 150.9 0.0 4.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Elf1 PF05129.13 KER26296.1 - 1.2e-27 95.7 1.2 1.2e-27 95.7 1.2 2.0 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Forkhead PF00250.18 KER26297.1 - 1.5e-33 114.9 0.0 3.6e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain Exo_endo_phos PF03372.23 KER26300.1 - 1.9e-10 40.6 0.1 3.4e-10 39.8 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.6 KER26300.1 - 2.4e-07 30.5 0.0 5.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KER26300.1 - 0.01 15.5 0.3 0.01 15.5 0.3 1.9 2 0 0 2 2 2 0 TAP C-terminal domain Ribosomal_S2 PF00318.20 KER26302.1 - 2.7e-38 131.4 0.0 3e-19 69.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 CAF1A PF12253.8 KER26303.1 - 9.9e-45 150.6 18.1 2.7e-24 85.1 11.0 4.4 4 1 0 4 4 4 2 Chromatin assembly factor 1 subunit A NTP_transf_3 PF12804.7 KER26303.1 - 0.0018 18.7 0.1 0.28 11.5 0.1 3.3 3 0 0 3 3 3 1 MobA-like NTP transferase domain CAF-1_p150 PF11600.8 KER26303.1 - 0.0044 16.7 53.2 0.0044 16.7 53.2 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.17 KER26303.1 - 0.28 11.3 5.5 0.3 11.2 2.7 2.3 2 0 0 2 2 2 0 DDHD domain Chorismate_synt PF01264.21 KER26303.1 - 0.29 9.8 0.7 0.58 8.8 0.7 1.4 1 0 0 1 1 1 0 Chorismate synthase Exonuc_VII_L PF02601.15 KER26303.1 - 5.1 6.6 14.4 11 5.5 14.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asn_synthase PF00733.21 KER26306.1 - 8.8e-18 65.1 2.8 8.2e-10 38.9 0.2 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KER26306.1 - 3.7e-05 23.6 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KER26306.1 - 0.00048 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 KER26306.1 - 0.04 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD synthase 7tm_1 PF00001.21 KER26307.1 - 1.8e-29 102.9 14.2 6.9e-29 101.0 10.3 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF1741 PF08427.10 KER26307.1 - 0.0092 15.7 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) HLH PF00010.26 KER26311.1 - 1.1e-11 44.5 0.1 3.9e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 KER26313.1 - 7.3e-35 120.6 0.0 9.6e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26313.1 - 7.1e-15 55.0 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER26313.1 - 0.006 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ArfGap PF01412.18 KER26315.1 - 3.3e-31 107.8 1.3 4.6e-31 107.3 0.2 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GxDLY PF14607.6 KER26315.1 - 0.091 12.6 1.0 3 7.6 0.2 2.5 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type FOXP-CC PF16159.5 KER26316.1 - 0.016 15.8 0.2 0.41 11.3 0.1 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KER26316.1 - 0.085 13.4 10.7 0.3 11.6 0.3 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KER26316.1 - 0.15 12.2 0.7 1.6 8.8 0.0 2.3 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_3rep PF18868.1 KER26316.1 - 0.19 12.4 2.1 0.36 11.5 2.1 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF4729 PF15866.5 KER26316.1 - 0.2 10.9 6.2 1.3 8.3 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) TFIIIC_sub6 PF10419.9 KER26317.1 - 3.6e-11 42.8 0.0 6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain RRM_1 PF00076.22 KER26318.1 - 4.8e-30 103.2 0.1 3.7e-16 58.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 KER26318.1 - 2.5e-07 30.9 20.4 4.1e-07 30.3 20.4 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein RRM_7 PF16367.5 KER26318.1 - 0.00045 20.3 0.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif SAE2 PF08573.10 KER26318.1 - 0.016 16.3 6.5 0.032 15.4 6.5 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus NPR3 PF03666.13 KER26318.1 - 0.61 8.8 4.6 1 8.1 4.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 KER26318.1 - 0.9 8.3 6.2 1.3 7.8 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 KER26318.1 - 1.8 8.5 8.1 3 7.8 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PRP38_assoc PF12871.7 KER26318.1 - 2.3 8.9 48.4 5.3 7.7 48.4 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term WD40 PF00400.32 KER26319.1 - 4.1e-09 36.9 9.4 0.0023 18.8 0.4 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER26319.1 - 9.7e-07 29.0 0.4 0.086 13.2 0.0 4.9 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CPT PF07931.12 KER26319.1 - 0.0019 18.1 0.2 0.0078 16.1 0.1 1.9 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein Tetraspanin PF00335.20 KER26321.1 - 1.5e-13 51.0 0.0 2.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Tetraspanin family YwiC PF14256.6 KER26321.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.2 3 0 0 3 3 3 0 YwiC-like protein Med14 PF08638.11 KER26322.1 - 3e-50 170.3 1.2 5e-50 169.6 1.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Tetraspanin PF00335.20 KER26323.1 - 0.0039 16.9 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Tetraspanin family COX16 PF14138.6 KER26323.1 - 1.3 9.6 5.7 3.7 8.1 2.0 3.0 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.32 KER26324.1 - 1.9e-07 31.6 6.8 0.015 16.1 0.6 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER26324.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SID-1_RNA_chan PF13965.6 KER26325.1 - 8.4e-201 668.5 0.1 1.9e-200 667.4 0.1 1.5 1 1 0 1 1 1 1 dsRNA-gated channel SID-1 Ceramidase PF05875.12 KER26325.1 - 0.00051 19.6 21.1 0.12 11.8 21.1 2.5 1 1 0 1 1 1 1 Ceramidase RDD PF06271.12 KER26327.1 - 5.1e-08 33.2 5.1 4.1e-06 27.1 5.1 3.0 1 1 0 1 1 1 1 RDD family DctQ PF04290.12 KER26327.1 - 0.066 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component F-box-like PF12937.7 KER26328.1 - 4e-12 45.8 2.2 4e-12 45.8 2.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER26328.1 - 9.4e-05 22.2 4.4 0.00044 20.0 4.4 2.1 1 1 0 1 1 1 1 F-box domain DUF836 PF05768.14 KER26329.1 - 3.3e-10 40.3 0.0 0.00044 20.6 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KER26329.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 KER26329.1 - 0.16 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4207 PF13904.6 KER26330.1 - 8.7e-20 71.5 28.9 1.4e-19 70.8 28.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) UQ_con PF00179.26 KER26331.1 - 1.1e-42 145.0 0.1 1.6e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER26331.1 - 0.0039 16.9 0.0 0.018 14.8 0.0 2.1 1 1 1 2 2 2 1 Prokaryotic E2 family B LRR_9 PF14580.6 KER26333.1 - 4.1e-10 39.4 1.3 0.0001 21.8 0.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KER26333.1 - 4.7e-10 39.6 21.5 5.6e-05 23.4 7.5 3.9 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER26333.1 - 3e-07 30.1 14.2 0.0067 16.2 3.1 4.3 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 KER26333.1 - 1.2 10.0 11.4 21 6.1 0.2 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat UMPH-1 PF05822.12 KER26334.1 - 2.1e-26 92.9 0.0 3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Exo_endo_phos PF03372.23 KER26334.1 - 0.11 12.0 0.3 1.3 8.4 0.1 2.7 2 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER26334.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase NADHdh_A3 PF14987.6 KER26336.1 - 0.01 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Asp PF00026.23 KER26338.1 - 1.5e-25 90.3 0.0 2.2e-11 43.8 0.0 2.7 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER26338.1 - 6.5e-05 23.2 0.0 0.0084 16.4 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TaqI_C PF12950.7 KER26342.1 - 0.11 12.6 0.3 0.56 10.3 0.1 2.2 2 1 0 2 2 2 0 TaqI-like C-terminal specificity domain TMEM108 PF15759.5 KER26344.1 - 0.0086 15.1 0.2 0.038 13.0 0.1 1.8 1 1 0 1 1 1 1 TMEM108 family Ets PF00178.22 KER26345.1 - 5.6e-34 116.5 1.8 1.1e-33 115.5 1.8 1.5 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.17 KER26345.1 - 0.046 14.3 0.1 0.2 12.3 0.1 2.2 1 0 0 1 1 1 0 HSF-type DNA-binding Endostatin PF06482.11 KER26346.1 - 7.1e-69 232.7 0.0 6.5e-59 199.9 0.0 2.1 1 1 1 2 2 2 2 Collagenase NC10 and Endostatin Collagen PF01391.18 KER26346.1 - 1 9.2 20.5 1.3e+02 2.5 20.5 2.6 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) SGL PF08450.12 KER26347.1 - 1.9e-12 47.3 0.2 0.00087 18.9 0.0 5.6 5 0 0 5 5 5 3 SMP-30/Gluconolactonase/LRE-like region BNR_2 PF13088.6 KER26347.1 - 6.6e-05 22.3 0.0 5.3 6.3 0.0 3.9 3 0 0 3 3 3 3 BNR repeat-like domain DUF2724 PF10893.8 KER26347.1 - 0.00034 20.4 0.0 1.2e+02 2.6 0.0 7.9 10 0 0 10 10 10 0 Protein of unknown function (DUF2724) ChiW_Ig_like PF18683.1 KER26347.1 - 1.5 9.1 10.6 80 3.5 0.1 5.3 5 0 0 5 5 5 0 Chitinase W immunoglobulin-like domain Peptidase_S8 PF00082.22 KER26352.1 - 2.2e-38 132.2 0.4 3.1e-38 131.7 0.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KER26352.1 - 2.3e-17 62.8 0.0 4.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.6 KER26352.1 - 0.00011 21.9 5.3 0.00011 21.9 5.3 8.3 4 2 4 8 8 8 3 Growth factor receptor domain IV Furin-like_2 PF15913.5 KER26352.1 - 0.0008 19.5 34.6 0.0012 19.0 9.6 7.1 6 3 2 8 8 8 3 Furin-like repeat, cysteine-rich Homeodomain PF00046.29 KER26355.1 - 1.4e-18 66.4 7.3 3.3e-18 65.3 7.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER26355.1 - 0.0085 16.0 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain 2Fe-2S_thioredx PF01257.19 KER26355.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Tubulin PF00091.25 KER26357.1 - 4.3e-51 173.9 0.0 6.4e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER26357.1 - 5.6e-38 129.9 0.0 9.8e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain zf-C3HC4_2 PF13923.6 KER26359.1 - 1.6e-12 47.0 27.7 5e-06 26.2 9.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER26359.1 - 8.5e-08 32.4 29.5 0.00057 20.2 8.9 3.3 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KER26359.1 - 9.7e-07 28.6 27.5 0.0041 17.0 9.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KER26359.1 - 6.3e-05 22.9 29.9 0.038 14.0 11.0 2.8 2 0 0 2 2 2 2 Zinc-finger zf-rbx1 PF12678.7 KER26359.1 - 0.00094 19.4 28.9 0.029 14.6 7.7 3.1 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KER26359.1 - 0.0038 17.1 26.0 0.29 11.1 9.0 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER26359.1 - 0.02 14.7 22.8 0.6 10.0 7.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMF_DNA_bd PF12329.8 KER26359.1 - 0.043 13.8 0.9 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-RING-like PF08746.11 KER26359.1 - 0.11 12.8 23.3 1.6 9.1 7.4 2.9 2 0 0 2 2 2 0 RING-like domain ANAPC3 PF12895.7 KER26359.1 - 0.18 12.0 2.0 0.33 11.2 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PSCyt3 PF07627.11 KER26359.1 - 0.27 11.6 5.4 3.5 7.9 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) FlgN PF05130.12 KER26362.1 - 0.033 14.7 2.5 0.054 14.0 2.1 1.5 1 1 0 1 1 1 0 FlgN protein TTL PF03133.15 KER26363.1 - 1.1e-75 254.6 1.1 1.4e-75 254.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER26363.1 - 1.5e-06 27.7 0.0 7.1e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER26363.1 - 0.0024 17.2 0.1 0.007 15.6 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF348 PF03990.14 KER26364.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain NSP2-B_epitope PF14757.6 KER26364.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein MYCBPAP PF14646.6 KER26368.1 - 4.9e-74 249.8 0.5 7.2e-74 249.3 0.5 1.2 1 0 0 1 1 1 1 MYCBP-associated protein family Iron_traffic PF04362.14 KER26368.1 - 0.27 11.0 2.1 6.5 6.5 0.4 2.7 3 0 0 3 3 3 0 Bacterial Fe(2+) trafficking Arm PF00514.23 KER26369.1 - 6e-07 29.3 35.2 0.015 15.4 0.6 10.4 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 KER26369.1 - 0.0008 19.5 3.9 0.39 10.8 0.1 5.1 5 1 1 6 6 6 1 V-ATPase subunit H RICTOR_V PF14668.6 KER26369.1 - 0.0031 17.7 3.3 0.42 10.9 0.1 3.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 LAM_C PF12544.8 KER26369.1 - 0.017 15.3 0.4 0.05 13.8 0.1 1.9 2 0 0 2 2 2 0 Lysine-2,3-aminomutase V-ATPase_H_N PF03224.14 KER26369.1 - 0.045 13.0 7.4 0.1 11.8 1.1 3.0 3 0 0 3 3 3 0 V-ATPase subunit H ASL_C PF08328.11 KER26369.1 - 0.11 12.6 0.2 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal HEAT_EZ PF13513.6 KER26369.1 - 0.25 11.9 7.2 31 5.2 0.3 5.0 5 0 0 5 5 5 0 HEAT-like repeat zf-C2H2 PF00096.26 KER26370.1 - 1.4e-18 66.2 81.9 6.6e-05 23.1 1.5 10.8 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER26370.1 - 1.8e-15 56.3 75.4 0.013 16.3 0.8 11.1 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER26370.1 - 7.8e-15 54.5 19.9 1.2e-09 38.1 0.3 10.6 14 0 0 14 14 11 4 Zinc-finger double domain FYDLN_acid PF09538.10 KER26370.1 - 0.0039 17.9 2.4 1.2 9.9 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.12 KER26370.1 - 0.02 15.2 52.9 0.089 13.1 8.8 6.7 5 3 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KER26370.1 - 0.034 13.7 2.4 1.5 8.5 0.2 3.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KER26370.1 - 0.052 13.3 46.7 0.96 9.3 0.1 8.2 8 0 0 8 8 7 0 C2H2-type zinc-finger domain DUF2207 PF09972.9 KER26370.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-C2H2_8 PF15909.5 KER26370.1 - 0.078 13.3 31.1 0.12 12.7 1.3 5.6 5 0 0 5 5 5 0 C2H2-type zinc ribbon CpXC PF14353.6 KER26370.1 - 0.088 12.9 6.5 8 6.5 0.0 4.9 5 0 0 5 5 5 0 CpXC protein zf-C2H2_aberr PF17017.5 KER26370.1 - 0.38 10.9 10.0 3.5 7.8 0.0 4.0 3 1 1 4 4 4 0 Aberrant zinc-finger PyrI_C PF02748.15 KER26370.1 - 0.97 9.4 9.0 6.6 6.7 0.5 4.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-TFIIB PF13453.6 KER26370.1 - 8 5.9 8.9 30 4.1 0.0 4.0 4 0 0 4 4 4 0 Transcription factor zinc-finger AA_permease_2 PF13520.6 KER26373.1 - 7.4e-42 143.7 22.5 7.4e-42 143.7 22.5 2.5 2 1 1 3 3 3 1 Amino acid permease AA_permease PF00324.21 KER26373.1 - 4.8e-28 98.0 24.1 4.8e-28 98.0 24.1 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KER26373.1 - 7e-17 61.2 9.1 7e-17 61.2 9.1 3.4 4 0 0 4 4 4 1 C-terminus of AA_permease DUF5084 PF16894.5 KER26373.1 - 0.058 13.8 5.6 3.6 8.0 1.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) ALAD PF00490.21 KER26376.1 - 2.3e-106 355.6 0.0 3.2e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MIF4G PF02854.19 KER26377.1 - 7.3e-17 61.7 3.6 1.4e-16 60.8 3.6 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KER26377.1 - 1.4e-08 34.7 0.1 6.8e-06 26.0 0.0 3.3 3 0 0 3 3 3 1 MA3 domain eIF_4EBP PF05456.11 KER26377.1 - 0.00093 19.1 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CNOT1_CAF1_bind PF16415.5 KER26377.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Phage_pRha PF09669.10 KER26378.1 - 0.075 13.6 0.4 0.1 13.1 0.4 1.2 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Band_7 PF01145.25 KER26381.1 - 1.4e-29 103.4 1.3 2.2e-29 102.7 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER26381.1 - 0.0048 16.6 0.1 0.0075 16.0 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KER26381.1 - 0.1 13.0 2.6 0.36 11.3 0.6 2.7 2 1 1 3 3 3 0 Phage protein Gp68 E1_DerP2_DerF2 PF02221.15 KER26385.1 - 3.5e-08 33.9 0.0 6.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 ML domain RE_TaqI PF09573.10 KER26385.1 - 0.0018 18.1 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 TaqI restriction endonuclease E1_DerP2_DerF2 PF02221.15 KER26386.1 - 4.6e-09 36.8 0.3 4.9e-09 36.7 0.3 1.0 1 0 0 1 1 1 1 ML domain Retrotran_gag_2 PF14223.6 KER26386.1 - 0.036 13.8 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type E1_DerP2_DerF2 PF02221.15 KER26387.1 - 7.5e-05 23.2 0.0 8.6e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KER26388.1 - 1.5e-05 25.4 0.2 0.0016 18.9 0.0 2.1 2 0 0 2 2 2 2 ML domain DUF5461 PF17545.2 KER26388.1 - 0.2 12.0 0.1 1.6 9.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5461) Trypsin PF00089.26 KER26389.1 - 1.3e-13 51.3 0.0 1.4e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin YecM PF06185.12 KER26389.1 - 0.096 12.3 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 YecM protein E1_DerP2_DerF2 PF02221.15 KER26390.1 - 4.3e-07 30.4 0.0 4.5e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 ML domain Ribosomal_L3 PF00297.22 KER26392.1 - 1.7e-97 326.7 3.4 8.4e-44 150.0 0.1 3.0 2 1 1 3 3 3 3 Ribosomal protein L3 VirB3 PF05101.13 KER26392.1 - 0.06 13.6 0.1 9.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF4051 PF13260.6 KER26392.1 - 0.12 12.1 10.2 3.3 7.5 0.7 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4051) NDK PF00334.19 KER26393.1 - 7.6e-29 100.4 0.0 1.5e-28 99.5 0.0 1.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase MG2 PF01835.19 KER26394.1 - 7.6e-10 39.1 0.0 2.3e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 MG2 domain A2M_BRD PF07703.14 KER26394.1 - 0.00044 20.6 0.0 0.056 13.8 0.0 3.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain DSL PF01414.19 KER26394.1 - 9 6.7 14.1 0.3 11.4 0.8 2.7 2 0 0 2 2 2 0 Delta serrate ligand RVT_1 PF00078.27 KER26395.1 - 7e-33 114.0 0.0 1.9e-32 112.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB PF00651.31 KER26395.1 - 1.5e-27 96.0 1.2 1.6e-26 92.7 0.1 2.7 3 0 0 3 3 3 1 BTB/POZ domain BACK PF07707.15 KER26395.1 - 5.3e-09 36.1 0.0 1.1e-07 31.9 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 KER26395.1 - 6.6e-07 29.5 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain RRM_1 PF00076.22 KER26397.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KER26397.1 - 0.0082 16.1 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 RL domain DUF411 PF04214.13 KER26397.1 - 0.031 14.2 0.2 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF Nup35_RRM_2 PF14605.6 KER26397.1 - 0.04 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-SCNM1 PF15803.5 KER26397.1 - 0.12 12.1 2.2 12 5.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 GOLD_2 PF13897.6 KER26398.1 - 1.1e-47 162.0 0.1 2.9e-47 160.6 0.1 1.8 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking RVT_1 PF00078.27 KER26398.1 - 9.8e-07 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Propeptide_C25 PF08126.11 KER26400.1 - 0.19 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Propeptide_C25 DUF929 PF06053.11 KER26401.1 - 0.095 12.0 3.8 0.12 11.7 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3139 PF11337.8 KER26401.1 - 0.32 11.7 5.0 0.54 11.0 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ODV-E18 PF10717.9 KER26401.1 - 0.44 10.5 3.4 0.69 9.8 3.4 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.11 KER26401.1 - 1.4 8.6 4.7 1.9 8.2 4.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Filament PF00038.21 KER26405.1 - 7.9e-24 84.8 48.1 1.4e-23 84.0 48.1 1.4 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KER26405.1 - 1.1e-07 32.2 0.0 0.0074 16.6 0.0 2.6 2 0 0 2 2 2 2 Lamin Tail Domain IKKbetaNEMObind PF12179.8 KER26405.1 - 0.0088 16.1 3.6 1.1 9.4 0.2 2.7 2 0 0 2 2 2 2 I-kappa-kinase-beta NEMO binding domain DUF4942 PF13708.6 KER26405.1 - 0.015 15.2 1.6 0.19 11.7 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) UDG PF03167.19 KER26406.1 - 2.8e-13 50.2 0.0 1.4e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily PAF PF15715.5 KER26406.1 - 0.045 14.4 1.1 0.11 13.1 1.1 1.6 1 0 0 1 1 1 0 PCNA-associated factor histone like domain RHS PF03527.14 KER26407.1 - 0.008 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 RHS protein Pkinase PF00069.25 KER26410.1 - 5.9e-27 94.7 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26410.1 - 1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SK_channel PF03530.14 KER26419.1 - 1.4e-38 131.4 4.4 1.4e-38 131.4 4.4 1.9 2 0 0 2 2 2 1 Calcium-activated SK potassium channel CaMBD PF02888.16 KER26419.1 - 3.4e-30 104.1 9.6 3.4e-30 104.1 9.6 2.0 2 0 0 2 2 2 1 Calmodulin binding domain Ion_trans_2 PF07885.16 KER26419.1 - 8.4e-14 51.3 2.5 8.4e-14 51.3 2.5 2.3 2 0 0 2 2 2 1 Ion channel Allexi_40kDa PF05549.11 KER26419.1 - 0.15 11.6 2.2 0.2 11.2 0.6 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein CBS PF00571.28 KER26421.1 - 1.7e-18 66.8 0.0 5.1e-08 33.2 0.0 3.4 3 0 0 3 3 3 3 CBS domain Homeodomain PF00046.29 KER26422.1 - 7.5e-15 54.5 8.5 1.7e-10 40.6 0.6 2.9 2 1 0 2 2 2 2 Homeodomain Homeodomain PF00046.29 KER26423.1 - 1.2e-21 76.3 9.7 2.3e-21 75.4 9.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER26423.1 - 0.1 12.5 0.6 0.25 11.3 0.6 1.7 1 0 0 1 1 1 0 Homeobox KN domain Terminase_5 PF06056.12 KER26423.1 - 0.17 11.8 0.2 0.45 10.5 0.2 1.7 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) NICE-1 PF15845.5 KER26426.1 - 0.28 12.0 4.7 0.26 12.1 2.7 1.9 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family TACC_C PF05010.14 KER26427.1 - 3.7e-44 150.9 24.2 3.7e-44 150.9 24.2 2.2 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF637 PF04830.13 KER26427.1 - 0.031 14.1 0.4 0.094 12.5 0.4 1.8 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) RPEL PF02755.15 KER26427.1 - 0.96 9.2 5.2 3.4 7.5 1.9 2.8 2 0 0 2 2 2 0 RPEL repeat Med9 PF07544.13 KER26427.1 - 4.8 7.3 10.7 0.61 10.2 1.7 3.7 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FH2 PF02181.23 KER26430.1 - 2.7e-23 82.7 2.1 3.5e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain DUF1287 PF06940.11 KER26430.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF3010 PF11215.8 KER26430.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) RIO1 PF01163.22 KER26431.1 - 6.5e-33 113.9 4.9 3.9e-25 88.5 0.0 2.5 3 0 0 3 3 3 2 RIO1 family Rio2_N PF09202.11 KER26431.1 - 9.4e-20 70.6 0.0 2.3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 KER26431.1 - 2.2e-05 23.9 0.2 0.00016 21.1 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER26431.1 - 0.0021 18.0 0.9 0.68 9.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Homeodomain PF00046.29 KER26435.1 - 7.9e-05 22.4 2.9 0.00015 21.6 2.9 1.4 1 0 0 1 1 1 1 Homeodomain Pkinase_Tyr PF07714.17 KER26437.1 - 7e-97 323.8 0.0 9.6e-97 323.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER26437.1 - 2.7e-51 174.5 0.0 3.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER26437.1 - 1.2e-20 73.4 0.6 2.5e-20 72.3 0.6 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KER26437.1 - 2.5e-14 52.6 0.0 1.4e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KER26437.1 - 2.7e-10 40.0 0.1 7.7e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KER26437.1 - 3.2e-08 33.1 0.2 5.4e-07 29.2 0.0 2.6 1 1 1 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 KER26437.1 - 0.00078 18.5 0.3 0.0027 16.7 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER26437.1 - 0.0068 16.4 0.1 0.085 12.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family SH3_16 PF18348.1 KER26437.1 - 0.032 14.0 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Rab_eff_C PF04698.12 KER26437.1 - 0.073 11.4 0.2 0.11 10.8 0.2 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus SH3_3 PF08239.11 KER26437.1 - 0.13 12.5 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain MatE PF01554.18 KER26438.1 - 1.7e-50 170.8 33.9 1.6e-30 105.9 8.3 2.7 3 0 0 3 3 3 2 MatE Med23 PF11573.8 KER26439.1 - 2.9e-43 147.9 1.5 7.5e-41 139.9 0.2 2.2 2 0 0 2 2 2 2 Mediator complex subunit 23 Toxin_GhoT_OrtT PF10753.9 KER26439.1 - 0.24 11.7 3.4 0.92 9.8 0.2 2.8 2 0 0 2 2 2 0 Toxin GhoT_OrtT Med23 PF11573.8 KER26440.1 - 8.5e-43 146.3 8.5 6.3e-11 40.7 0.0 6.1 6 0 0 6 6 6 6 Mediator complex subunit 23 Peptidase_A17 PF05380.13 KER26441.1 - 3e-32 111.9 0.7 7.4e-32 110.6 0.7 1.6 1 1 0 1 1 1 1 Pao retrotransposon peptidase HXXEE PF13787.6 KER26442.1 - 0.092 13.6 0.1 0.17 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF4131 PF13567.6 KER26442.1 - 0.14 11.8 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 KER26442.1 - 0.19 10.4 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 KER26442.1 - 0.5 10.3 6.2 0.19 11.6 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RNA_pol_Rpb2_6 PF00562.28 KER26444.1 - 3.8e-128 427.9 0.2 5.5e-128 427.3 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KER26444.1 - 3e-66 222.8 0.0 4.2e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KER26444.1 - 9e-51 172.2 0.4 2.1e-50 171.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KER26444.1 - 5.5e-33 113.2 0.1 1.2e-32 112.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KER26444.1 - 5.3e-24 84.2 0.0 1.3e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KER26444.1 - 1.2e-21 76.8 2.7 1.5e-21 76.5 1.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KER26444.1 - 2.5e-10 40.8 0.0 7e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ank_3 PF13606.6 KER26446.1 - 0.022 15.3 0.1 0.078 13.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KER26446.1 - 0.073 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NFACT-R_1 PF05670.13 KER26449.1 - 3e-42 143.7 0.0 4.9e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain SIMPL PF04402.14 KER26449.1 - 0.00026 21.5 1.0 0.00031 21.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DBINO PF13892.6 KER26449.1 - 0.029 14.7 10.0 0.049 14.0 10.0 1.4 1 0 0 1 1 1 0 DNA-binding domain DUF2514 PF10721.9 KER26449.1 - 0.048 13.7 7.0 0.068 13.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TFX_C PF14601.6 KER26449.1 - 0.051 13.5 0.1 0.66 10.0 0.0 2.5 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term HI0933_like PF03486.14 KER26449.1 - 0.1 11.2 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein PEARLI-4 PF05278.12 KER26449.1 - 0.73 9.4 8.9 1.1 8.8 8.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HMG_CoA_synt_N PF01154.17 KER26450.1 - 2.6e-74 248.9 0.0 3.7e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KER26450.1 - 7.6e-72 242.3 0.0 8.9e-39 133.8 0.0 2.1 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 KER26450.1 - 0.04 14.1 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PDZ PF00595.24 KER26451.1 - 1.1e-26 92.9 0.0 3.3e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER26451.1 - 2.1e-26 91.5 0.0 2.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER26451.1 - 5e-15 55.6 0.0 1.1e-06 28.9 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_4 PF17816.1 KER26451.1 - 0.00027 21.3 0.0 0.11 12.9 0.0 2.7 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 KER26451.1 - 0.0059 16.5 0.0 0.43 10.6 0.0 2.6 2 1 0 2 2 2 1 Tricorn protease PDZ domain GRASP55_65 PF04495.14 KER26451.1 - 0.062 13.6 0.0 15 5.9 0.0 2.3 1 1 1 2 2 2 0 GRASP55/65 PDZ-like domain EF-hand_6 PF13405.6 KER26452.1 - 2.8e-18 64.2 10.3 2.4e-08 33.2 0.3 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 KER26452.1 - 7.9e-18 64.7 8.3 1.1e-12 48.2 1.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER26452.1 - 3.6e-17 60.5 13.8 3.5e-09 35.5 0.5 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KER26452.1 - 3.4e-09 35.8 10.0 9.7e-06 24.9 0.5 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KER26452.1 - 4.9e-07 29.5 11.7 6e-07 29.2 1.8 3.9 3 1 1 4 4 4 1 EF-hand domain pair p25-alpha PF05517.12 KER26452.1 - 0.00033 20.9 0.8 0.00079 19.6 0.6 1.7 1 1 0 1 1 1 1 p25-alpha EF-hand_4 PF12763.7 KER26452.1 - 0.0015 18.5 3.0 0.0018 18.2 0.2 2.4 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KER26452.1 - 0.0071 16.3 0.3 0.078 12.9 0.1 2.2 1 1 1 2 2 2 2 Caleosin related protein DUF842 PF05811.13 KER26452.1 - 0.048 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) NPA PF16469.5 KER26452.1 - 0.25 11.9 4.8 1.3 9.6 0.0 3.0 3 1 0 3 3 3 0 Nematode polyprotein allergen ABA-1 EF-hand_9 PF14658.6 KER26452.1 - 0.82 10.0 3.7 15 6.0 0.0 3.6 3 1 1 4 4 4 0 EF-hand domain DUF676 PF05057.14 KER26453.1 - 1.7e-45 155.3 0.0 3.7e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 KER26453.1 - 1e-14 54.8 3.0 1.1e-14 54.7 1.1 2.1 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 KER26453.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KER26453.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein MAP7 PF05672.11 KER26454.1 - 8.3e-05 22.3 34.5 8.3e-05 22.3 34.5 2.4 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family ERM PF00769.19 KER26454.1 - 0.0034 17.2 23.2 0.0034 17.2 23.2 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family PsbU PF06514.11 KER26454.1 - 0.33 11.0 1.3 0.48 10.4 0.1 1.8 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) P22_portal PF16510.5 KER26454.1 - 5.9 5.4 10.1 11 4.5 10.1 1.3 1 0 0 1 1 1 0 Phage P22-like portal protein FliD_N PF02465.18 KER26455.1 - 0.033 14.9 0.5 0.054 14.2 0.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Tctex-1 PF03645.13 KER26457.1 - 0.0057 16.9 0.0 0.0076 16.5 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family ASC PF00858.24 KER26458.1 - 2.1e-43 148.9 0.0 3.7e-43 148.1 0.0 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF1497 PF07384.11 KER26459.1 - 0.01 16.2 0.2 0.054 13.9 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Imm71 PF15602.6 KER26459.1 - 0.026 14.6 4.7 0.057 13.5 4.7 1.6 1 0 0 1 1 1 0 Immunity protein 71 Bacillus_HBL PF05791.11 KER26459.1 - 0.04 13.8 6.6 0.73 9.6 6.6 2.2 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin-6_N PF09177.11 KER26459.1 - 0.33 11.5 9.2 5.4 7.6 9.2 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HTH_19 PF12844.7 KER26459.1 - 1.6 8.8 8.4 8.6 6.5 2.4 3.2 2 1 0 2 2 2 0 Helix-turn-helix domain FUSC PF04632.12 KER26459.1 - 2.3 6.6 7.3 0.69 8.4 4.3 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family C5-epim_C PF06662.13 KER26460.1 - 2.6e-53 180.3 0.0 7.5e-45 152.7 0.0 2.3 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus RRM_7 PF16367.5 KER26461.1 - 1.6e-28 98.6 0.0 1e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KER26461.1 - 4.4e-23 81.3 3.3 9.4e-23 80.2 3.3 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KER26461.1 - 1.5e-06 27.9 0.0 0.0079 16.0 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KER26461.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain zf-B_box PF00643.24 KER26461.1 - 0.076 13.2 3.7 0.18 11.9 3.7 1.6 1 0 0 1 1 1 0 B-box zinc finger Unpaired PF15972.5 KER26461.1 - 0.11 12.0 0.4 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 Unpaired protein zinc_ribbon_10 PF10058.9 KER26461.1 - 3 7.7 6.0 7.1 6.4 6.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2706 PF10913.8 KER26462.1 - 0.24 11.3 0.7 0.67 9.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) HSP20 PF00011.21 KER26464.1 - 7.4e-13 48.5 0.0 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family FDF PF09532.10 KER26465.1 - 0.0021 18.9 2.3 0.0057 17.5 2.3 1.8 1 1 0 1 1 1 1 FDF domain RT_RNaseH_2 PF17919.1 KER26465.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase YjeF_N PF03853.15 KER26465.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus PRP38 PF03371.15 KER26466.1 - 0.066 13.1 0.4 8.2 6.3 0.1 2.2 2 0 0 2 2 2 0 PRP38 family DM PF00751.18 KER26467.1 - 8.4e-29 99.2 31.6 2.3e-14 53.0 14.1 2.6 2 0 0 2 2 2 2 DM DNA binding domain zf-C3HC PF07967.13 KER26467.1 - 0.94 9.5 6.3 0.14 12.2 0.4 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like Anti-TRAP PF15777.5 KER26467.1 - 3.5 7.7 7.4 13 5.8 0.4 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MTABC_N PF16185.5 KER26469.1 - 1.6e-55 188.2 11.2 1.6e-55 188.2 11.2 1.5 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 KER26469.1 - 3.1e-15 56.6 2.8 3.1e-15 56.6 2.8 3.1 3 1 0 3 3 3 2 ABC transporter transmembrane region DUF4293 PF14126.6 KER26469.1 - 7.3 6.8 16.2 0.18 12.0 6.7 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) PAP2 PF01569.21 KER26471.1 - 5.1e-07 29.5 0.5 9.1e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily UPF0114 PF03350.16 KER26471.1 - 0.068 13.4 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 GCP_C_terminal PF04130.13 KER26472.1 - 3.2e-39 135.2 0.2 5.9e-39 134.3 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KER26472.1 - 2.5e-23 83.2 0.1 4e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal 3HCDH_N PF02737.18 KER26473.1 - 4.1e-54 183.2 0.0 5.3e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KER26473.1 - 1.2e-26 93.2 0.0 2.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KER26473.1 - 9.4e-05 22.6 0.0 0.00038 20.6 0.0 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KER26473.1 - 0.00017 21.6 0.1 0.00073 19.5 0.1 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 KER26473.1 - 0.0071 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KER26473.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KER26473.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain rRNA_proc-arch PF13234.6 KER26474.1 - 6.4e-71 239.4 0.0 1.1e-70 238.7 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KER26474.1 - 8.4e-56 188.1 0.9 8.4e-56 188.1 0.9 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KER26474.1 - 5.3e-19 68.7 0.0 5.6e-18 65.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KER26474.1 - 7.1e-06 26.1 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER26474.1 - 0.0067 16.7 0.0 0.073 13.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain EF-hand_14 PF17959.1 KER26474.1 - 0.038 14.3 0.2 0.14 12.5 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain GlnE PF03710.15 KER26474.1 - 0.071 12.5 0.7 7.1 6.0 0.0 2.8 3 0 0 3 3 3 0 Glutamate-ammonia ligase adenylyltransferase PhoH PF02562.16 KER26474.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Ecm29 PF13001.7 KER26480.1 - 1.1e-59 202.5 0.0 5.1e-32 111.2 0.0 3.2 1 1 1 2 2 2 2 Proteasome stabiliser RVT_1 PF00078.27 KER26480.1 - 7.9e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_2 PF13646.6 KER26480.1 - 0.00037 20.8 20.9 0.37 11.2 0.0 7.6 8 1 2 10 10 10 4 HEAT repeats HEAT PF02985.22 KER26480.1 - 0.007 16.5 20.2 0.13 12.6 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.23 KER26480.1 - 0.011 15.7 0.4 0.63 10.2 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Kei1 PF08552.11 KER26480.1 - 0.12 12.2 1.5 0.31 10.9 1.5 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1077 PF06417.12 KER26482.1 - 9.4e-40 135.3 0.3 1.3e-39 134.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Exo_endo_phos PF03372.23 KER26483.1 - 3.9e-16 59.3 0.0 3.6e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KER26483.1 - 2.7e-08 34.0 12.5 0.00017 21.9 2.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LANC_like PF05147.13 KER26485.1 - 1.8e-61 207.7 0.0 2.3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein PPTA PF01239.22 KER26487.1 - 2.5e-39 131.9 10.5 9.7e-12 44.2 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF1759 PF03564.15 KER26488.1 - 0.0023 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) HTH_AsnC-type PF13404.6 KER26488.1 - 0.03 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain WD40 PF00400.32 KER26490.1 - 7.1e-08 33.0 17.6 0.17 12.8 0.2 5.9 6 2 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER26490.1 - 6.3e-05 23.2 0.0 0.072 13.4 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CRT10 PF08728.10 KER26490.1 - 0.047 11.9 0.0 0.85 7.7 0.0 2.1 2 0 0 2 2 2 0 CRT10 FXR_C1 PF16096.5 KER26491.1 - 0.054 13.7 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 LSM PF01423.22 KER26492.1 - 3.9e-16 58.5 1.2 5.3e-16 58.1 1.2 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 KER26492.1 - 0.063 13.2 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 KER26492.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 Hfq protein DUF1298 PF06974.13 KER26494.1 - 0.0082 16.1 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1298) Kinesin PF00225.23 KER26495.1 - 3.2e-73 246.5 0.4 9.7e-73 245.0 0.4 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER26495.1 - 1e-14 54.7 0.4 2.7e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Zeta_toxin PF06414.12 KER26495.1 - 0.0091 15.3 1.3 1.1 8.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KER26495.1 - 0.012 16.0 0.3 0.55 10.7 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1951 PF09188.10 KER26495.1 - 0.098 12.6 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) AAA_30 PF13604.6 KER26495.1 - 0.12 12.1 0.5 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KER26495.1 - 0.22 11.8 4.6 0.54 10.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain Cas6b_C PF17262.2 KER26495.1 - 0.59 10.3 2.6 1.6 8.8 2.6 1.7 1 0 0 1 1 1 0 Cas6b C-terminal domain Phe_tRNA-synt_N PF02912.18 KER26495.1 - 3.2 7.8 6.7 12 5.9 0.9 3.1 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain MFS_1 PF07690.16 KER26496.1 - 1.3e-16 60.5 41.6 2.7e-09 36.4 8.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Hormone_recep PF00104.30 KER26498.1 - 7.2e-05 22.5 0.3 0.00018 21.2 0.3 1.6 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Prok-RING_1 PF14446.6 KER26498.1 - 0.032 14.1 2.6 0.086 12.8 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KER26498.1 - 0.15 12.0 3.6 0.46 10.5 3.6 1.9 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-C4 PF00105.18 KER26498.1 - 0.22 12.0 10.8 0.46 11.0 10.8 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF2318 PF10080.9 KER26498.1 - 0.92 9.7 6.2 1.8 8.8 6.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PHD PF00628.29 KER26498.1 - 3 7.8 10.5 6.6 6.7 10.5 1.6 1 1 0 1 1 1 0 PHD-finger Ank_4 PF13637.6 KER26500.1 - 1.8e-29 101.7 6.4 2.1e-14 53.7 0.6 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER26500.1 - 1.1e-27 95.7 6.3 2.9e-11 43.4 0.7 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER26500.1 - 2.5e-24 85.7 0.2 4.7e-18 65.6 0.3 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER26500.1 - 5.2e-21 72.5 4.0 3e-08 33.3 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KER26500.1 - 1.4e-19 69.5 5.1 9.7e-08 32.1 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeat Pro_isomerase PF00160.21 KER26501.1 - 2.5e-42 144.8 0.1 5.9e-42 143.6 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KER26501.1 - 8.1e-19 67.2 0.0 1.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 KER26501.1 - 0.00095 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4944) PROCT PF08084.11 KER26501.1 - 0.062 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 PROCT (NUC072) domain RRM_5 PF13893.6 KER26501.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER26501.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif UPF0139 PF03669.13 KER26502.1 - 2.7e-26 91.3 0.0 3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) TFIIE_beta PF02186.15 KER26503.1 - 6.7e-18 64.7 0.1 1.6e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain WW PF00397.26 KER26503.1 - 2.3e-06 27.6 0.0 0.062 13.4 0.2 2.7 2 0 0 2 2 2 2 WW domain TFA2_Winged_2 PF18121.1 KER26503.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 adh_short PF00106.25 KER26503.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER26503.1 - 0.0047 16.9 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Coprogen_oxidas PF01218.18 KER26503.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase NusG PF02357.19 KER26503.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 Transcription termination factor nusG NDUF_C2 PF06374.11 KER26504.1 - 1.9e-10 40.9 0.0 2e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) CdhD PF03599.16 KER26504.1 - 0.019 13.7 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Pkinase PF00069.25 KER26505.1 - 2.2e-34 119.0 0.0 3.5e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER26505.1 - 6.8e-34 117.3 0.0 2.6e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER26505.1 - 0.025 13.4 0.0 0.17 10.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF3012 PF11216.8 KER26505.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) MAGI_u5 PF16666.5 KER26505.1 - 0.76 9.9 5.5 0.32 11.2 1.2 2.1 2 0 0 2 2 2 0 Unstructured region on MAGI BON PF04972.17 KER26507.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 BON domain BAF PF02961.14 KER26508.1 - 6.7e-32 109.8 0.0 1.5e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Barrier to autointegration factor RVT_1 PF00078.27 KER26508.1 - 0.0039 16.7 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IMS_HHH PF11798.8 KER26508.1 - 0.012 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 IMS family HHH motif zf-C2H2_4 PF13894.6 KER26510.1 - 4e-18 64.6 47.5 0.00014 22.4 2.9 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KER26510.1 - 4.6e-18 64.6 48.6 5.4e-05 23.4 2.9 6.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER26510.1 - 7.6e-11 41.9 36.8 0.012 16.0 0.0 7.5 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 KER26510.1 - 2.6e-08 33.5 43.5 0.00055 19.6 1.8 5.9 6 0 0 6 6 6 4 zinc-finger C2H2-type zf-met PF12874.7 KER26510.1 - 8.3e-07 29.2 21.2 0.0033 17.7 0.2 6.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KER26510.1 - 0.0012 18.7 20.0 0.11 12.4 1.2 4.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KER26510.1 - 0.0013 19.4 14.4 0.22 12.3 1.9 3.6 2 1 1 3 3 3 2 zinc-ribbon family zf-C2H2_jaz PF12171.8 KER26510.1 - 0.0019 18.4 23.7 0.0026 18.0 0.6 5.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER26510.1 - 0.0068 16.4 33.4 0.075 13.1 0.2 6.5 6 0 0 6 6 6 1 C2H2-type zinc finger zf-Di19 PF05605.12 KER26510.1 - 0.012 15.9 35.6 0.15 12.4 6.9 4.4 2 1 3 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KER26510.1 - 0.014 15.9 0.1 0.014 15.9 0.1 4.6 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 KER26510.1 - 0.015 16.0 19.0 0.047 14.4 1.4 3.5 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats HalOD2 PF18547.1 KER26510.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.8 3 0 0 3 3 2 0 Halobacterial output domain 2 zf-FCS PF06467.14 KER26510.1 - 0.4 10.7 16.9 3.5 7.6 0.1 4.7 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 KER26510.1 - 0.46 10.1 21.8 7.4 6.3 0.7 6.0 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KER26510.1 - 0.71 10.0 18.9 1.5 9.0 3.7 4.0 3 1 2 5 5 5 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 KER26510.1 - 1 9.2 26.1 0.36 10.6 0.7 5.4 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KER26510.1 - 1.2 9.5 28.7 3.9 7.9 1.4 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF5472 PF17566.2 KER26510.1 - 6.1 6.9 7.3 7.4 6.6 0.2 3.4 2 2 2 4 4 4 0 Family of unknown function (DUF5472) zf-C2H2_8 PF15909.5 KER26510.1 - 6.4 7.1 20.3 2.3 8.5 1.3 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon FYVE PF01363.21 KER26510.1 - 8.1 6.7 32.1 5 7.3 6.3 4.4 1 1 3 4 4 4 0 FYVE zinc finger PDZ PF00595.24 KER26511.1 - 1.2e-29 102.5 0.0 1.6e-12 47.5 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KER26511.1 - 4.5e-17 61.6 0.5 3.9e-07 29.8 0.1 3.9 4 0 0 4 4 4 2 PDZ domain RVT_1 PF00078.27 KER26511.1 - 1.8e-09 37.4 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-TRAF PF02176.18 KER26511.1 - 1.3e-07 32.2 6.6 0.0068 17.1 0.7 2.9 2 0 0 2 2 2 2 TRAF-type zinc finger PDZ_2 PF13180.6 KER26511.1 - 4.1e-07 30.2 0.0 0.00013 22.2 0.0 3.0 3 0 0 3 3 2 1 PDZ domain zf-TRAF_2 PF15965.5 KER26511.1 - 4.4e-07 30.3 17.6 0.00079 19.8 1.4 3.3 2 1 1 3 3 3 2 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 KER26511.1 - 1.1e-05 25.4 1.9 3.7e-05 23.7 1.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER26511.1 - 1.4e-05 25.0 0.6 5.4e-05 23.1 0.6 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER26511.1 - 0.00013 21.7 1.0 0.00057 19.7 1.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER26511.1 - 0.00018 21.3 2.1 0.00061 19.6 2.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER26511.1 - 0.00047 20.4 0.8 0.004 17.5 0.8 2.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KER26511.1 - 0.0042 17.2 1.0 0.018 15.2 1.0 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KER26511.1 - 0.0087 16.3 0.7 0.031 14.6 0.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KER26511.1 - 0.017 15.0 0.6 0.06 13.2 0.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) La PF05383.17 KER26512.1 - 1.2e-16 60.5 0.1 2.2e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 La domain Ank_2 PF12796.7 KER26514.1 - 3.3e-05 24.4 0.0 6.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KER26514.1 - 0.00013 22.2 0.3 0.00086 19.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KER26514.1 - 0.0032 17.9 0.1 1.3 9.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KER26514.1 - 0.037 14.4 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) C2 PF00168.30 KER26515.1 - 1.1e-08 35.3 0.1 1.3e-08 35.1 0.1 1.0 1 0 0 1 1 1 1 C2 domain Copine PF07002.16 KER26517.1 - 5e-80 268.0 0.0 8.2e-80 267.3 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 KER26517.1 - 8e-06 26.1 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus WD40 PF00400.32 KER26521.1 - 3.8e-25 87.7 10.9 0.00068 20.4 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER26521.1 - 5.6e-14 52.2 0.3 0.0047 17.2 0.0 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER26521.1 - 3.4e-06 27.1 0.9 0.027 14.3 0.1 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KER26521.1 - 0.00043 20.1 0.2 8.5 6.0 0.0 3.6 1 1 1 3 3 3 2 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KER26521.1 - 0.00068 18.7 0.5 2.3 7.1 0.1 3.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KER26521.1 - 0.0043 16.4 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 KER26521.1 - 0.0075 15.6 0.2 0.71 9.2 0.0 3.1 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Edc3_linker PF16598.5 KER26523.1 - 0.13 12.9 0.0 0.16 12.6 0.0 1.1 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 RNA_pol_Rpb6 PF01192.22 KER26525.1 - 5.3e-17 61.5 0.2 9.1e-17 60.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 HTH_33 PF13592.6 KER26526.1 - 0.033 13.8 0.4 0.069 12.8 0.4 1.5 1 0 0 1 1 1 0 Winged helix-turn helix SNF2_N PF00176.23 KER26527.1 - 4.8e-67 226.1 0.8 4.8e-67 226.1 0.8 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER26527.1 - 6e-19 68.4 0.0 1.4e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 KER26527.1 - 4.9e-09 36.4 6.9 5.5e-09 36.2 4.0 2.6 1 1 1 2 2 2 1 HSA Marek_A PF02124.15 KER26528.1 - 0.029 14.2 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF5519 PF17648.1 KER26528.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Bul1_C PF04426.12 KER26529.1 - 0.034 13.6 0.4 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Bul1 C terminus FGF PF00167.18 KER26529.1 - 0.12 12.5 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Fibroblast growth factor CSD PF00313.22 KER26530.1 - 3e-26 91.1 0.5 5.9e-26 90.1 0.5 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KER26530.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Amidase PF01425.21 KER26531.1 - 3.1e-15 56.1 0.1 3.5e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 Amidase RVT_1 PF00078.27 KER26533.1 - 1.2e-11 44.6 0.0 6.1e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amidase PF01425.21 KER26533.1 - 0.21 10.5 0.0 0.42 9.5 0.0 1.3 1 1 0 1 1 1 0 Amidase Amidase PF01425.21 KER26534.1 - 1.2e-65 222.2 1.8 2.3e-65 221.3 1.8 1.3 1 1 0 1 1 1 1 Amidase CENP-L PF13092.6 KER26534.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 adh_short PF00106.25 KER26535.1 - 2.2e-27 95.8 0.0 1.2e-20 73.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KER26535.1 - 2.5e-17 63.3 0.0 5.2e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER26535.1 - 2e-05 24.5 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KER26535.1 - 0.044 13.2 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 7tm_1 PF00001.21 KER26537.1 - 4.5e-17 62.2 1.2 5.8e-17 61.9 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER26537.1 - 0.011 15.4 5.2 0.055 13.1 5.2 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx FtsJ PF01728.19 KER26542.1 - 6.1e-54 182.8 0.0 1e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 KER26542.1 - 2.7e-36 125.2 22.5 2.7e-36 125.2 22.5 3.3 3 1 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.8 KER26542.1 - 9.1e-22 77.6 18.4 1.7e-16 60.5 0.0 5.7 5 2 1 6 6 6 2 Domain of unknown function (DUF3381) NB-ARC PF00931.22 KER26544.1 - 2.4e-14 53.1 0.0 1.1e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain APAF1_C PF17908.1 KER26544.1 - 3.1e-11 43.4 0.6 2.2e-08 34.2 0.2 2.7 2 0 0 2 2 2 2 APAF-1 helical domain WD40 PF00400.32 KER26544.1 - 5.9e-08 33.3 24.5 0.0001 23.0 0.8 9.4 10 0 0 10 10 10 2 WD domain, G-beta repeat CARD PF00619.21 KER26544.1 - 2.1e-06 27.7 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KER26544.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.6 KER26544.1 - 1.7e-05 25.2 0.0 5.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KER26544.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PQQ_2 PF13360.6 KER26544.1 - 0.088 12.4 0.8 15 5.1 0.0 3.0 4 0 0 4 4 4 0 PQQ-like domain AAA_22 PF13401.6 KER26544.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SQHop_cyclase_C PF13243.6 KER26544.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Cadherin PF00028.17 KER26546.1 - 1.8e-33 114.9 0.1 7.1e-10 39.2 0.0 5.5 4 2 1 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 KER26546.1 - 0.0032 17.5 2.4 4.5 7.3 0.1 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin PF00028.17 KER26547.1 - 2.3e-25 88.8 3.6 4.4e-13 49.5 0.2 3.5 4 0 0 4 4 4 2 Cadherin domain Cadherin_pro PF08758.11 KER26547.1 - 5.7e-06 26.4 0.0 5e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Cadherin prodomain like DUF1684 PF07920.11 KER26547.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Fcf1 PF04900.12 KER26548.1 - 3.2e-31 107.6 4.2 3.2e-31 107.6 4.2 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KER26548.1 - 3e-10 40.4 0.0 5.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 PIN like domain AnfG_VnfG PF03139.15 KER26548.1 - 0.037 14.1 0.2 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit DUF5615 PF18480.1 KER26548.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) MFS_1 PF07690.16 KER26549.1 - 0.00027 20.0 2.6 0.00041 19.4 2.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Herpes_glycop PF01528.16 KER26549.1 - 0.033 13.1 3.8 0.052 12.4 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M MFS_1 PF07690.16 KER26550.1 - 4.7e-27 94.8 28.3 1.3e-13 50.6 6.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily SH2 PF00017.24 KER26552.1 - 5.8e-25 87.2 0.0 2.4e-15 56.4 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RVT_1 PF00078.27 KER26552.1 - 1.4e-22 80.3 0.0 2.7e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 KER26552.1 - 1.4e-12 47.7 0.2 3.4e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 KER26552.1 - 8.4e-08 32.0 19.2 0.002 18.0 0.6 3.5 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RsbU_N PF08673.10 KER26552.1 - 0.0042 17.2 0.3 0.41 10.8 0.0 2.7 2 0 0 2 2 2 1 Phosphoserine phosphatase RsbU, N-terminal domain SAM_1 PF00536.30 KER26552.1 - 0.011 16.2 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SabA_adhesion PF18304.1 KER26552.1 - 0.026 13.8 0.6 0.043 13.1 0.6 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain SH2_2 PF14633.6 KER26552.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 SH2 domain PHD PF00628.29 KER26552.1 - 0.95 9.4 16.1 1.1 9.2 0.5 2.7 2 0 0 2 2 2 0 PHD-finger ATG16 PF08614.11 KER26552.1 - 2.7 8.2 13.0 6.2 7.0 13.0 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-HC5HC2H_2 PF13832.6 KER26552.1 - 3.8 7.7 11.8 16 5.7 0.1 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain Ras PF00071.22 KER26553.1 - 3.9e-57 192.4 0.0 5e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER26553.1 - 5e-29 101.0 0.0 1e-28 100.0 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER26553.1 - 4.9e-11 42.4 0.0 6.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER26553.1 - 0.0032 16.9 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KER26553.1 - 0.0091 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TRAP_alpha PF03896.16 KER26555.1 - 4.9e-41 140.8 0.0 6.8e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Reticulon PF02453.17 KER26556.1 - 0.00049 20.1 4.1 0.00077 19.5 4.1 1.2 1 0 0 1 1 1 1 Reticulon BTB PF00651.31 KER26557.1 - 1.1e-14 54.6 0.6 3.4e-14 53.0 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 KER26557.1 - 2.4e-06 27.6 0.1 0.00034 20.7 0.1 3.1 3 0 0 3 3 3 1 BTB And C-terminal Kelch Peroxin-3 PF04882.12 KER26557.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Peroxin-3 KIAA1430 PF13879.6 KER26559.1 - 0.14 12.9 2.7 0.096 13.5 0.6 1.8 1 1 1 2 2 2 0 KIAA1430 homologue Cnd2 PF05786.14 KER26561.1 - 0.085 11.5 4.4 0.1 11.3 4.4 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Dynein_light PF01221.18 KER26562.1 - 3.2e-29 101.1 0.5 3.6e-29 100.9 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phage_cap_E PF03864.15 KER26562.1 - 0.079 12.1 0.0 0.087 12.0 0.0 1.0 1 0 0 1 1 1 0 Phage major capsid protein E PI3_PI4_kinase PF00454.27 KER26565.1 - 1.1e-37 130.2 0.0 2.3e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 KER26565.1 - 1.4e-19 70.0 0.0 3.8e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 KER26565.1 - 1.8e-13 50.0 0.3 5.6e-13 48.5 0.3 2.0 1 0 0 1 1 1 1 FATC domain Ank_2 PF12796.7 KER26565.1 - 1e-10 42.0 0.1 5.2e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER26565.1 - 4.6e-08 33.5 0.3 7.1e-07 29.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER26565.1 - 0.0001 22.4 0.2 11 7.0 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KER26565.1 - 0.0023 18.2 0.1 0.089 13.1 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) FRB_dom PF08771.11 KER26565.1 - 0.017 15.5 1.1 9.1 6.8 0.1 3.6 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Ank PF00023.30 KER26565.1 - 0.1 13.1 0.1 4.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Neur_chan_LBD PF02931.23 KER26566.1 - 8.5e-30 103.8 0.6 2.3e-23 82.8 0.2 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER26566.1 - 2.8e-18 66.9 0.0 1.3e-08 35.2 2.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF3267 PF11667.8 KER26566.1 - 0.019 15.3 1.0 0.019 15.3 1.0 1.6 2 0 0 2 2 2 0 Putative zincin peptidase MgtE PF01769.16 KER26566.1 - 0.09 13.2 0.2 0.09 13.2 0.2 1.7 2 0 0 2 2 2 0 Divalent cation transporter GBS_Bsp-like PF08481.10 KER26566.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 GBS Bsp-like repeat Neur_chan_LBD PF02931.23 KER26567.1 - 2e-51 174.5 1.8 3e-51 173.9 1.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER26567.1 - 5.4e-32 111.8 0.1 2e-23 83.7 0.0 2.5 3 0 0 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region AvrB_AvrC PF05394.11 KER26567.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein Neur_chan_memb PF02932.16 KER26568.1 - 1.1e-20 74.7 6.2 1.7e-20 74.1 6.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KER26568.1 - 3.4e-06 26.7 0.1 4.8e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.9 KER26568.1 - 0.11 11.9 5.6 0.19 11.1 5.6 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF5090 PF17009.5 KER26568.1 - 0.76 9.7 9.0 1.1 9.2 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF3267 PF11667.8 KER26568.1 - 9.4 6.6 12.5 2.7 8.3 8.4 2.1 1 1 1 2 2 2 0 Putative zincin peptidase ER_lumen_recept PF00810.18 KER26569.1 - 6.8e-49 166.5 6.2 6.5e-24 85.4 0.1 2.8 3 0 0 3 3 3 2 ER lumen protein retaining receptor TMEM238 PF15125.6 KER26569.1 - 0.025 14.8 5.2 2.1 8.6 1.1 2.6 2 0 0 2 2 2 0 TMEM238 protein family PQ-loop PF04193.14 KER26569.1 - 0.064 13.0 1.3 9.4 6.1 0.1 2.8 2 0 0 2 2 2 0 PQ loop repeat DUF485 PF04341.12 KER26569.1 - 1.1 9.2 11.2 4.1 7.4 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function, DUF485 2OG-FeII_Oxy_3 PF13640.6 KER26570.1 - 8.3e-10 39.4 0.2 0.0004 21.2 0.1 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KER26570.1 - 3.4e-08 33.9 0.2 0.0024 18.3 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 KER26570.1 - 6.9e-08 32.2 0.1 0.42 10.0 0.0 4.7 4 1 0 5 5 5 4 Anp1 Pox_A3L PF05288.11 KER26570.1 - 0.001 19.0 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Poxvirus A3L Protein Arc_C PF18162.1 KER26570.1 - 0.002 18.0 0.1 0.26 11.1 0.0 3.8 4 0 0 4 4 4 1 Arc C-lobe DUF3148 PF11347.8 KER26570.1 - 0.0061 16.3 0.4 3.3 7.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3148) Rx_N PF18052.1 KER26570.1 - 0.072 13.4 1.3 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Rx N-terminal domain FAD_binding_4 PF01565.23 KER26570.1 - 0.16 11.7 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain PPI_Ypi1 PF07491.11 KER26571.1 - 0.079 12.8 0.7 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor RRM_1 PF00076.22 KER26572.1 - 3.1e-18 65.3 0.0 4.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_fiss_reg PF05308.11 KER26573.1 - 0.019 15.0 5.5 0.059 13.4 5.5 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator p31comet PF06581.12 KER26573.1 - 0.075 12.2 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding DUF3829 PF12889.7 KER26573.1 - 0.093 12.2 0.0 0.093 12.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) DUF2312 PF10073.9 KER26573.1 - 0.099 12.3 0.3 0.33 10.6 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) JIP_LZII PF16471.5 KER26573.1 - 0.94 9.7 13.6 0.056 13.6 1.0 3.9 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II NYD-SP28_assoc PF14775.6 KER26573.1 - 5.2 7.3 10.0 6 7.0 0.1 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain Joubert PF15392.6 KER26575.1 - 0.00054 19.8 3.2 0.0019 18.0 0.0 3.0 1 1 1 2 2 2 1 Joubert syndrome-associated DUF1258 PF06869.12 KER26576.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) Spc42p PF11544.8 KER26576.1 - 0.17 11.9 0.3 0.35 10.9 0.3 1.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p KH_1 PF00013.29 KER26577.1 - 2.2e-07 30.6 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 KH domain EIF_2_alpha PF07541.12 KER26577.1 - 0.045 13.8 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Neur_chan_LBD PF02931.23 KER26580.1 - 2.9e-51 174.0 3.0 4.3e-51 173.4 3.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER26580.1 - 1.5e-21 77.6 1.4 3.3e-21 76.5 1.4 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HypA PF01155.19 KER26580.1 - 0.054 13.5 1.1 5.4 7.1 0.1 2.7 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Neur_chan_LBD PF02931.23 KER26582.1 - 5.9e-49 166.4 2.9 8.2e-49 166.0 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER26582.1 - 3.6e-24 86.1 2.7 4e-24 86.0 0.2 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Mic1 PF07035.12 KER26583.1 - 5.6e-41 139.9 4.9 1.1e-40 138.9 4.9 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like ASTN_2_hairpin PF18577.1 KER26583.1 - 0.0047 17.0 0.1 14 5.9 0.0 3.7 4 0 0 4 4 4 2 Astrotactin-2 C-terminal beta-hairpin domain DUF3510 PF12022.8 KER26583.1 - 0.039 14.3 0.0 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Surp PF01805.20 KER26585.1 - 9.3e-45 150.4 5.9 3.3e-23 81.4 0.3 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 KER26585.1 - 1.4e-42 146.1 0.4 1.1e-40 139.9 0.4 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein SMC_ScpA PF02616.14 KER26585.1 - 0.18 11.6 0.7 0.36 10.7 0.7 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Surp PF01805.20 KER26587.1 - 5e-45 151.3 5.9 2.5e-23 81.8 0.3 2.6 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 KER26587.1 - 6.7e-43 147.1 0.4 6.3e-41 140.6 0.4 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein SMC_ScpA PF02616.14 KER26587.1 - 0.12 12.3 0.7 0.25 11.2 0.7 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA MCM PF00493.23 KER26590.1 - 2.9e-97 324.2 0.0 8.3e-97 322.7 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KER26590.1 - 8.3e-31 106.5 0.0 1.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER26590.1 - 1.1e-17 64.2 1.4 2.5e-17 63.1 1.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KER26590.1 - 8.3e-16 58.5 0.7 1.9e-15 57.3 0.3 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KER26590.1 - 3e-06 26.8 0.0 5.2e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KER26590.1 - 0.00014 21.8 0.0 0.00065 19.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KER26590.1 - 0.025 14.4 1.6 0.036 13.9 0.3 1.9 2 0 0 2 2 2 0 AAA lid domain AAA_3 PF07726.11 KER26590.1 - 0.042 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FHA PF00498.26 KER26591.1 - 0.049 14.0 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 FHA domain Importin_rep_4 PF18808.1 KER26594.1 - 1e-25 89.8 5.5 7.1e-23 80.7 3.1 4.1 2 1 0 2 2 2 1 Importin repeat HEAT PF02985.22 KER26594.1 - 2.9e-22 76.8 3.6 0.00051 20.1 0.0 9.3 8 0 0 8 8 7 3 HEAT repeat HEAT_EZ PF13513.6 KER26594.1 - 1.7e-17 63.5 3.7 1.2e-06 28.8 0.0 8.2 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 KER26594.1 - 2.4e-15 56.7 5.2 2.5e-06 27.8 0.2 7.6 6 2 1 8 8 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KER26594.1 - 1.2e-10 41.8 0.0 0.00042 20.9 0.0 6.6 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KER26594.1 - 1.1e-07 32.0 0.0 2.1e-06 27.9 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KER26594.1 - 2.7e-06 27.1 0.0 0.086 12.4 0.0 4.3 3 0 0 3 3 3 1 CLASP N terminal RIX1 PF08167.12 KER26594.1 - 3.7e-05 23.6 0.0 0.49 10.1 0.0 4.8 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 KER26594.1 - 5.4e-05 23.3 4.1 0.00072 19.7 0.2 3.2 3 0 0 3 3 3 1 Importin repeat 6 IBN_N PF03810.19 KER26594.1 - 7.4e-05 22.6 1.7 0.0021 17.9 0.0 4.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KER26594.1 - 0.00051 20.0 2.3 0.086 12.9 0.2 5.4 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KER26594.1 - 0.00054 19.6 0.0 0.91 9.0 0.0 3.3 2 1 1 3 3 3 2 Tti2 family DUF3385 PF11865.8 KER26594.1 - 0.00082 19.3 0.3 2.6 7.9 0.1 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) Importin_rep_5 PF18816.1 KER26594.1 - 0.0012 19.1 0.0 0.019 15.2 0.0 2.8 2 0 0 2 2 2 1 Importin repeat HBB PF06777.11 KER26594.1 - 0.024 14.3 0.1 0.06 13.0 0.1 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain Gcn1_N PF12074.8 KER26594.1 - 0.027 13.8 0.1 0.76 9.0 0.0 2.7 2 1 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF4061 PF13270.6 KER26594.1 - 0.047 14.0 0.1 0.18 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) MMS19_C PF12460.8 KER26594.1 - 0.07 12.2 2.1 0.97 8.5 0.1 3.6 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal CarboxypepD_reg PF13620.6 KER26595.1 - 3.6e-24 84.8 6.5 5.8e-05 23.3 0.0 7.8 7 1 0 7 7 7 5 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KER26595.1 - 3.4e-11 43.3 0.0 0.27 11.5 0.0 7.0 8 1 0 8 8 8 3 SdrD B-like domain CarbopepD_reg_2 PF13715.6 KER26595.1 - 1.8e-08 34.2 0.3 0.047 13.7 0.0 6.1 7 0 0 7 7 7 2 CarboxypepD_reg-like domain SpaA PF17802.1 KER26595.1 - 6.2e-08 32.9 0.0 0.2 12.0 0.0 4.2 3 1 0 3 3 3 3 Prealbumin-like fold domain fn3_3 PF14686.6 KER26595.1 - 0.007 16.1 0.1 44 4.0 0.0 4.7 4 0 0 4 4 4 0 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.13 KER26595.1 - 0.15 12.0 0.0 1.2e+02 2.7 0.0 4.3 5 0 0 5 5 5 0 Y_Y_Y domain RVT_1 PF00078.27 KER26596.1 - 0.00052 19.6 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1939 PF09154.10 KER26596.1 - 0.00081 19.5 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1939) TMEM52 PF14979.6 KER26597.1 - 0.015 15.2 1.5 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Transmembrane 52 CLPTM1 PF05602.12 KER26599.1 - 1.8e-137 458.9 1.1 2.3e-137 458.5 1.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KER26599.1 - 0.023 14.4 3.8 0.63 9.8 0.2 3.0 2 0 0 2 2 2 0 PQ loop repeat LPP PF04728.13 KER26601.1 - 0.012 15.9 4.4 0.75 10.2 0.1 3.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper ApoO PF09769.9 KER26601.1 - 0.28 11.1 5.6 1.5 8.8 0.3 2.9 3 0 0 3 3 3 0 Apolipoprotein O DUF4407 PF14362.6 KER26601.1 - 1 8.7 32.3 15 4.9 25.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2046 PF09755.9 KER26601.1 - 1.7 7.8 45.9 0.14 11.3 26.9 3.6 1 1 3 4 4 4 0 Uncharacterized conserved protein H4 (DUF2046) VPS11_C PF12451.8 KER26601.1 - 4.3 7.6 7.7 16 5.8 0.1 4.0 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal OmpH PF03938.14 KER26601.1 - 5.2 7.4 43.0 0.41 11.0 11.7 4.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Peptidase_M16_C PF05193.21 KER26602.1 - 9.9e-28 97.4 0.0 1.4e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KER26603.1 - 9.2e-11 41.9 0.0 0.00017 21.6 0.0 2.1 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Chlorosome_CsmC PF11098.8 KER26603.1 - 0.028 14.4 0.0 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Chlorosome envelope protein C AF0941-like PF14591.6 KER26603.1 - 0.1 13.1 0.0 82 3.8 0.0 3.1 3 0 0 3 3 3 0 AF0941-like PNPase PF03726.14 KER26603.1 - 0.15 12.6 0.1 30 5.2 0.0 2.4 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Peptidase_M16 PF00675.20 KER26604.1 - 3.4e-07 30.3 0.0 6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF1231 PF06802.11 KER26604.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) PDZ PF00595.24 KER26606.1 - 1.5e-46 156.6 1.4 1.5e-19 70.1 0.0 3.3 2 1 1 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KER26606.1 - 6.9e-20 70.6 5.6 7.2e-10 38.6 0.1 3.7 3 1 1 4 4 4 3 PDZ domain L27_1 PF09058.10 KER26606.1 - 1.7e-13 50.4 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 L27_1 PDZ_2 PF13180.6 KER26606.1 - 3.6e-10 40.0 0.6 0.0026 18.0 0.0 3.4 2 1 1 3 3 3 2 PDZ domain Mucin PF01456.17 KER26606.1 - 0.063 13.3 1.5 0.079 13.0 0.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein PMEI PF04043.15 KER26608.1 - 0.093 13.1 0.3 0.16 12.3 0.3 1.3 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Pet127 PF08634.10 KER26610.1 - 0.1 12.0 2.3 8.9 5.7 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet127 SRR1 PF07985.12 KER26610.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 SRR1 Ank_2 PF12796.7 KER26611.1 - 1.1e-83 275.8 20.7 1.8e-12 47.6 0.9 9.4 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER26611.1 - 9e-78 255.7 24.6 5e-09 36.5 0.9 12.1 7 2 7 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER26611.1 - 9.3e-64 210.7 34.4 1e-06 28.9 0.0 16.3 7 4 10 17 17 17 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER26611.1 - 3.9e-59 189.6 26.8 0.00082 19.6 0.0 17.7 18 0 0 18 18 18 14 Ankyrin repeat Ank PF00023.30 KER26611.1 - 1.8e-54 179.9 27.9 0.0014 19.0 0.0 17.4 17 1 0 17 17 17 14 Ankyrin repeat Ion_trans PF00520.31 KER26611.1 - 1.3e-07 31.2 22.4 2.2e-07 30.4 22.4 1.4 1 0 0 1 1 1 1 Ion transport protein Phage_T7_Capsid PF05396.11 KER26611.1 - 0.00011 22.6 1.3 0.76 10.1 0.0 4.3 4 1 1 5 5 5 2 Phage T7 capsid assembly protein Tfb5 PF06331.12 KER26611.1 - 0.041 13.9 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 XendoU PF09412.10 KER26613.1 - 1.9e-39 135.5 0.6 3.8e-27 95.2 0.1 2.0 1 1 1 2 2 2 2 Endoribonuclease XendoU F-box-like PF12937.7 KER26614.1 - 1.7e-11 43.8 0.4 7.2e-11 41.8 0.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER26614.1 - 8.3e-10 38.3 0.1 3.4e-09 36.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KER26614.1 - 0.00032 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 F-box LRR_6 PF13516.6 KER26614.1 - 0.0037 17.2 19.1 2.3 8.5 0.1 8.2 10 0 0 10 10 10 1 Leucine Rich repeat LRR_4 PF12799.7 KER26614.1 - 0.39 11.2 14.2 0.9 10.1 0.3 5.7 3 2 4 8 8 8 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER26614.1 - 2.8 8.9 22.6 6.8 7.7 0.2 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat Hep_core_N PF08290.11 KER26614.1 - 4.5 7.3 8.0 11 6.2 0.1 3.8 3 0 0 3 3 3 0 Hepatitis core protein, putative zinc finger Ig_2 PF13895.6 KER26615.1 - 0.0039 17.5 0.0 0.58 10.5 0.0 3.5 2 1 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 KER26615.1 - 0.0045 17.6 0.0 0.39 11.3 0.0 3.6 3 1 0 3 3 3 1 Immunoglobulin domain TSP_1 PF00090.19 KER26615.1 - 0.0046 17.1 31.0 1 9.6 11.1 3.8 2 2 0 2 2 2 2 Thrombospondin type 1 domain V-set PF07686.17 KER26615.1 - 0.0047 17.1 0.1 0.15 12.2 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KER26615.1 - 0.061 13.4 0.2 4.7 7.4 0.1 3.1 2 1 0 2 2 2 0 Immunoglobulin I-set domain ig PF00047.25 KER26615.1 - 0.1 12.8 0.0 12 6.1 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain Adap_comp_sub PF00928.21 KER26617.1 - 7e-58 196.1 0.0 1.6e-57 194.9 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family rve PF00665.26 KER26617.1 - 1.9e-14 53.8 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Clat_adaptor_s PF01217.20 KER26617.1 - 3e-07 30.5 0.2 5.9e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain rve_3 PF13683.6 KER26617.1 - 0.0036 17.1 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF460 PF04312.13 KER26617.1 - 0.073 12.8 0.2 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF460) Mito_carr PF00153.27 KER26618.1 - 1.1e-58 195.2 5.3 1.7e-18 66.3 0.3 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein HEAT_2 PF13646.6 KER26621.1 - 0.01 16.2 4.4 2.5 8.6 0.1 3.8 4 0 0 4 4 4 0 HEAT repeats LisH PF08513.11 KER26621.1 - 0.012 15.5 1.9 0.66 10.0 0.0 3.3 3 0 0 3 3 3 0 LisH Ribosomal_L6e PF01159.19 KER26624.1 - 4.4e-35 120.6 0.4 4.4e-35 120.6 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L6e PDZ PF00595.24 KER26626.1 - 2.2e-24 85.6 0.0 2.6e-13 50.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 KER26626.1 - 9.3e-20 70.2 0.0 1.4e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER26626.1 - 2.1e-09 37.6 0.0 0.00023 21.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Sp38 PF07354.12 KER26626.1 - 0.0012 18.4 0.5 0.0012 18.4 0.5 1.7 2 0 0 2 2 2 1 Zona-pellucida-binding protein (Sp38) zf-trcl PF13451.6 KER26626.1 - 0.034 14.0 0.1 17 5.4 0.0 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-P11 PF03854.14 KER26626.1 - 3 7.6 15.1 3.2 7.5 0.1 3.5 3 0 0 3 3 3 0 P-11 zinc finger DUF4476 PF14771.6 KER26627.1 - 2.2e-10 40.7 0.1 1.7e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) MTS PF05175.14 KER26627.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AAA_assoc_2 PF16193.5 KER26627.1 - 0.1 13.0 0.0 1.1 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA C-terminal domain DUF5585 PF17823.1 KER26628.1 - 0.049 12.6 0.1 0.069 12.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DSPc PF00782.20 KER26629.1 - 4.4e-33 113.9 0.0 6.2e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER26629.1 - 0.0021 17.6 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ran_BP1 PF00638.18 KER26630.1 - 0.16 12.2 0.0 2.5 8.4 0.0 2.2 2 0 0 2 2 2 0 RanBP1 domain ECH_1 PF00378.20 KER26632.1 - 2e-26 92.8 0.0 5e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Chromo PF00385.24 KER26632.1 - 4.4e-11 42.5 0.0 8.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ECH_2 PF16113.5 KER26632.1 - 1.8e-08 34.3 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase SpoVAD PF07451.11 KER26632.1 - 0.073 11.8 0.9 0.13 10.9 0.9 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) UPF0302 PF08864.10 KER26632.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain DUF4507 PF14964.6 KER26634.1 - 3.5e-09 36.1 0.0 5.1e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) DRTGG PF07085.12 KER26637.1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.7 1 1 0 2 2 2 0 DRTGG domain Pkinase PF00069.25 KER26638.1 - 3.6e-24 85.5 0.0 4.7e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER26638.1 - 3e-10 39.8 0.0 8.9e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH PF17917.1 KER26639.1 - 8.5e-20 71.0 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER26639.1 - 1.1e-17 63.9 0.1 2e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KER26639.1 - 1.9e-16 59.9 0.0 3.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Ldl_recept_a PF00057.18 KER26642.1 - 2.6e-41 139.6 90.7 5.7e-11 42.4 12.0 7.8 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 KER26642.1 - 9.9e-07 28.9 6.8 9.9e-07 28.9 6.8 5.1 4 1 0 4 4 4 2 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 KER26642.1 - 6.8e-06 26.5 11.0 0.11 12.9 0.0 4.7 5 0 0 5 5 5 4 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.7 KER26642.1 - 0.0031 17.7 3.9 0.0031 17.7 3.9 5.7 6 0 0 6 6 6 1 EGF domain Nipped-B_C PF12830.7 KER26644.1 - 3.3e-61 206.6 0.0 2.1e-60 204.0 0.0 2.6 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KER26644.1 - 0.0017 18.6 0.8 0.0017 18.6 0.8 4.3 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KER26644.1 - 0.016 15.3 0.3 0.72 9.9 0.1 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KER26644.1 - 0.027 15.0 1.9 1.6 9.3 0.2 4.9 6 1 1 7 7 7 0 HEAT-like repeat HEAT PF02985.22 KER26644.1 - 1.1 9.7 4.3 17 6.0 0.2 4.6 5 0 0 5 5 5 0 HEAT repeat YniB PF14002.6 KER26645.1 - 0.048 13.4 0.1 0.057 13.2 0.1 1.1 1 0 0 1 1 1 0 YniB-like protein GPP34 PF05719.11 KER26646.1 - 1.3e-53 182.1 0.1 1.7e-53 181.7 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF3919 PF13057.6 KER26647.1 - 2.3 7.8 5.9 3.4 7.2 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) MT-A70 PF05063.14 KER26648.1 - 5.6e-55 185.9 0.0 9e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 MT-A70 DUF4498 PF14926.6 KER26648.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) SSF PF00474.17 KER26650.1 - 1.4e-113 379.9 19.8 4.7e-106 355.0 6.9 2.2 1 1 1 2 2 2 2 Sodium:solute symporter family Ribonucleas_3_3 PF14622.6 KER26651.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease-III-like WGG PF10273.9 KER26652.1 - 1.7e-12 47.8 0.0 2.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Peptidase_M18 PF02127.15 KER26654.1 - 4.3e-147 490.4 0.0 6e-147 489.9 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) HTH_psq PF05225.16 KER26654.1 - 3e-06 26.9 0.0 7.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Peptidase_M42 PF05343.14 KER26654.1 - 0.038 13.0 0.0 0.11 11.5 0.0 1.7 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase PrmC_N PF17827.1 KER26656.1 - 0.14 12.7 0.4 0.36 11.5 0.4 1.9 1 1 0 1 1 1 0 PrmC N-terminal domain Adenine_deam_C PF13382.6 KER26657.1 - 0.045 13.1 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain SLD5_C PF16922.5 KER26657.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 DNA replication complex GINS protein SLD5 C-terminus DSPc PF00782.20 KER26658.1 - 9.7e-15 54.6 0.1 1.3e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain KTI12 PF08433.10 KER26659.1 - 3.6e-17 62.7 0.3 4e-12 46.2 1.0 2.1 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 KER26659.1 - 1.4e-09 38.3 0.0 7.2e-09 35.9 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KER26659.1 - 5.6e-05 23.6 0.0 0.00017 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KER26659.1 - 0.00033 21.2 0.0 0.003 18.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KER26659.1 - 0.0037 17.3 0.1 0.032 14.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase CNOT11 PF10155.9 KER26659.1 - 0.048 13.8 1.6 0.21 11.8 0.0 2.3 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 CEP63 PF17045.5 KER26659.1 - 0.048 13.6 4.8 0.071 13.0 4.8 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa CPT PF07931.12 KER26659.1 - 0.086 12.7 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CLP1_P PF16575.5 KER26659.1 - 0.1 12.4 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop bZIP_2 PF07716.15 KER26660.1 - 0.66 10.1 9.3 0.35 11.0 1.4 3.6 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 KER26660.1 - 0.83 9.8 12.1 0.24 11.5 1.7 3.4 3 1 1 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.8 KER26660.1 - 2 8.4 14.9 0.02 14.9 2.8 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 KER26660.1 - 8.2 6.9 6.2 4 7.9 2.5 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper WD40_3 PF15911.5 KER26661.1 - 3.5e-18 65.4 0.0 9.3e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.20 KER26661.1 - 2.1e-10 40.6 6.3 0.0046 16.8 0.1 5.2 2 1 3 5 5 5 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KER26661.1 - 4.7e-06 25.9 6.3 0.0014 17.8 0.0 4.5 3 1 2 5 5 5 1 Coatomer WD associated region TPR_2 PF07719.17 KER26661.1 - 0.0011 18.9 30.2 8.6 6.7 0.2 9.8 11 0 0 11 11 9 2 Tetratricopeptide repeat DZR PF12773.7 KER26661.1 - 0.0018 18.3 3.5 0.0082 16.2 3.5 2.1 1 1 0 1 1 1 1 Double zinc ribbon ANAPC3 PF12895.7 KER26661.1 - 0.0037 17.5 19.9 1.2 9.4 0.3 7.1 7 2 1 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER26661.1 - 0.005 17.5 32.0 1.9 9.5 3.0 9.3 8 1 3 11 11 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER26661.1 - 0.0069 16.3 9.8 7.4 6.8 0.6 7.7 7 2 1 8 8 8 1 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KER26661.1 - 0.015 15.6 0.0 8.8 6.7 0.0 3.4 4 0 0 4 4 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 KER26661.1 - 0.031 14.1 21.7 2.9 7.8 0.0 8.0 8 1 0 8 8 8 0 Tetratricopeptide repeat SNAP PF14938.6 KER26661.1 - 0.21 11.0 10.8 0.078 12.4 6.5 2.5 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP zf-UDP PF14569.6 KER26661.1 - 0.27 11.4 1.7 1.1 9.5 1.7 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger TPR_19 PF14559.6 KER26661.1 - 0.52 10.9 24.0 11 6.6 0.3 7.1 6 2 2 8 8 8 0 Tetratricopeptide repeat DUF410 PF04190.13 KER26661.1 - 0.79 9.5 3.9 0.96 9.2 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF410) TPR_8 PF13181.6 KER26661.1 - 2.3 8.6 18.0 8.7 6.8 0.3 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat Vps36-NZF-N PF16988.5 KER26661.1 - 6.2 6.3 8.6 0.26 10.7 1.9 2.1 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TES PF08034.11 KER26664.1 - 6.4e-25 87.2 16.9 6.4e-25 87.2 16.9 5.5 3 2 2 5 5 5 3 Trematode eggshell synthesis protein tRNA_int_end_N2 PF12928.7 KER26665.1 - 1.4e-07 31.6 0.0 6.6e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term Anoctamin PF04547.12 KER26666.1 - 1.4e-121 406.5 8.0 1.7e-121 406.2 8.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PIG-P PF08510.12 KER26668.1 - 2.1e-26 92.2 0.6 2.5e-26 92.0 0.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KER26668.1 - 0.028 14.7 10.6 0.076 13.3 9.9 2.0 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HRG PF16954.5 KER26668.1 - 0.21 12.0 3.5 0.38 11.2 3.5 1.5 1 1 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene FixQ PF05545.11 KER26668.1 - 2.8 8.0 7.8 1.7 8.6 1.2 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Methyltransf_15 PF09445.10 KER26669.1 - 4.6e-18 65.4 0.0 2.1e-14 53.4 0.0 2.5 2 1 0 2 2 2 2 RNA cap guanine-N2 methyltransferase LSM PF01423.22 KER26672.1 - 6.5e-16 57.8 0.5 8.9e-16 57.3 0.5 1.2 1 0 0 1 1 1 1 LSM domain DM PF00751.18 KER26674.1 - 2.5e-29 100.9 31.6 1.2e-15 57.1 9.2 2.6 2 0 0 2 2 2 2 DM DNA binding domain zf-C3HC PF07967.13 KER26674.1 - 0.24 11.4 10.9 0.82 9.7 1.1 3.5 3 0 0 3 3 3 0 C3HC zinc finger-like IBR PF01485.21 KER26675.1 - 7.7e-20 70.9 28.5 1.4e-11 44.4 1.2 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 KER26675.1 - 6.5e-13 49.0 0.1 1.2e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 KER26675.1 - 0.00048 20.0 4.9 0.00048 20.0 4.9 4.1 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_11 PF17123.5 KER26675.1 - 0.34 10.7 6.0 12 5.8 3.8 3.4 2 1 0 2 2 2 0 RING-like zinc finger zf-4CXXC_R1 PF10497.9 KER26675.1 - 3.1 8.1 20.4 9.6 6.5 4.2 3.6 3 1 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 KER26675.1 - 9 6.7 33.6 0.12 12.8 5.0 3.9 3 0 0 3 3 3 0 Ring finger domain IRS PF02174.17 KER26676.1 - 5.3e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Cadherin PF00028.17 KER26677.1 - 1.8e-38 130.9 9.6 2.5e-11 43.8 0.1 8.4 7 2 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 KER26677.1 - 3.9e-06 26.6 0.0 0.17 11.8 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 KER26677.1 - 0.0035 17.3 5.4 11 6.0 0.0 4.6 4 0 0 4 4 4 2 Cadherin-like PBP PF01161.20 KER26677.1 - 0.0067 16.7 0.0 0.12 12.7 0.0 2.9 1 1 1 2 2 2 1 Phosphatidylethanolamine-binding protein DUF2207 PF09972.9 KER26677.1 - 0.033 13.0 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KER26677.1 - 0.05 14.5 0.0 0.15 13.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 KER26677.1 - 0.11 12.9 0.3 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Gram_pos_anchor PF00746.21 KER26677.1 - 0.16 11.9 0.2 0.36 10.8 0.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SAC3_GANP PF03399.16 KER26678.1 - 1.9e-105 352.5 1.2 1.9e-105 352.5 1.2 2.6 3 0 0 3 3 3 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KER26678.1 - 0.008 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 KER26678.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.27 KER26679.1 - 1.5e-25 89.8 0.0 3.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PPP1R35_C PF15503.6 KER26680.1 - 1.4e-36 125.4 1.5 3e-36 124.4 1.5 1.6 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus MRF_C1 PF13887.6 KER26682.1 - 0.042 13.0 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Sec7 PF01369.20 KER26683.1 - 1.7e-27 96.3 0.0 3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KER26683.1 - 7e-10 39.0 0.0 1.1e-06 28.6 0.2 2.3 2 0 0 2 2 2 2 PH domain zf-ACC PF17848.1 KER26684.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Kunitz_BPTI PF00014.23 KER26685.1 - 2.3e-29 101.4 20.7 1.7e-14 53.8 1.3 2.5 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain RRM_1 PF00076.22 KER26686.1 - 6.9e-17 61.0 0.0 2.9e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER26686.1 - 0.0027 17.7 0.0 0.084 12.9 0.0 2.7 2 1 1 3 3 3 1 RNA binding motif Binary_toxB PF03495.14 KER26686.1 - 0.13 12.5 0.2 0.46 10.7 0.2 1.9 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DUF2205 PF10224.9 KER26687.1 - 2.2e-26 91.7 2.1 3.9e-26 90.8 2.1 1.4 1 0 0 1 1 1 1 Short coiled-coil protein KASH_CCD PF14662.6 KER26687.1 - 0.00075 19.4 2.3 0.0011 18.8 2.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KER26687.1 - 0.011 15.9 0.3 0.023 14.8 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KER26687.1 - 0.02 15.5 1.9 0.038 14.6 1.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 KER26687.1 - 0.11 12.7 1.6 6.2 7.1 0.3 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 KER26687.1 - 0.13 12.7 2.7 0.24 11.9 2.3 1.7 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 KER26687.1 - 0.16 12.4 4.5 0.11 13.0 2.2 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NIBRIN_BRCT_II PF16508.5 KER26689.1 - 1.2e-24 86.9 0.0 2.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT_2 PF16589.5 KER26689.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain He_PIG_assoc PF10632.9 KER26689.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Spt4 PF06093.13 KER26690.1 - 1e-30 105.7 0.9 1.2e-30 105.4 0.9 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C4 PF00105.18 KER26690.1 - 0.0048 17.3 0.3 0.0079 16.6 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ank_4 PF13637.6 KER26692.1 - 4.4e-44 148.3 0.7 3.8e-10 40.1 0.0 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER26692.1 - 4.4e-39 132.9 0.0 5.1e-12 46.2 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER26692.1 - 1.2e-28 95.9 6.0 3.9e-06 26.8 0.0 8.7 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KER26692.1 - 3.7e-26 90.9 2.9 7e-08 32.6 0.0 6.7 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KER26692.1 - 1.1e-25 88.9 11.7 4.5e-05 23.7 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat DUF1843 PF08898.10 KER26692.1 - 0.0022 18.5 0.4 4.1 8.0 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1843) NTP_transferase PF00483.23 KER26694.1 - 1.5e-31 109.8 0.0 2.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase RVT_1 PF00078.27 KER26694.1 - 1.5e-13 50.8 0.0 7e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hexapep PF00132.24 KER26694.1 - 3e-07 29.9 8.2 1.9e-05 24.2 0.1 3.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KER26694.1 - 0.00011 22.7 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Innexin PF00876.18 KER26696.1 - 1.3e-101 340.4 3.3 1.5e-101 340.2 3.3 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 KER26696.1 - 0.049 13.1 2.3 0.6 9.6 0.6 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B ABC_tran PF00005.27 KER26701.1 - 3.2e-35 121.6 0.0 5.4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KER26701.1 - 1.5e-19 70.7 6.3 1.9e-19 70.4 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KER26701.1 - 1.2e-06 28.2 3.7 3.3e-06 26.7 0.7 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KER26701.1 - 0.00022 21.2 0.0 0.00056 19.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KER26701.1 - 0.00049 20.5 0.1 0.0013 19.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KER26701.1 - 0.0034 17.1 0.1 0.012 15.4 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KER26701.1 - 0.0064 16.5 0.4 0.18 11.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER26701.1 - 0.014 15.7 0.0 0.044 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 KER26701.1 - 0.031 14.4 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KER26701.1 - 0.039 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KER26701.1 - 0.046 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KER26701.1 - 0.056 13.5 0.2 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 KER26701.1 - 0.075 12.7 0.4 0.87 9.3 0.1 2.3 1 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KER26701.1 - 0.082 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KER26701.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KER26701.1 - 0.13 12.3 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KER26701.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER26701.1 - 0.2 12.1 0.0 0.48 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TMEM208_SND2 PF05620.11 KER26701.1 - 6.3 6.5 6.9 0.41 10.4 0.1 2.3 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Serpin PF00079.20 KER26702.1 - 3.2e-64 217.6 0.0 3.9e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ANAPC3 PF12895.7 KER26703.1 - 2.3e-18 66.2 14.5 4.6e-15 55.6 5.5 5.0 5 2 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KER26703.1 - 2.4e-16 58.5 12.8 0.15 12.2 0.2 10.3 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER26703.1 - 1.5e-14 54.0 18.6 8.9e-05 22.7 0.0 7.5 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KER26703.1 - 5.5e-14 51.3 10.0 0.16 11.8 0.0 9.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KER26703.1 - 1.8e-11 43.3 3.3 0.83 10.0 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER26703.1 - 4e-11 42.1 9.7 0.014 15.4 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER26703.1 - 1.9e-10 41.2 3.6 0.015 15.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER26703.1 - 6.8e-10 38.9 5.6 0.44 11.5 0.1 7.3 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER26703.1 - 7.4e-10 38.4 1.1 0.26 11.0 0.0 6.6 4 2 2 6 6 6 2 TPR repeat TPR_19 PF14559.6 KER26703.1 - 2.8e-06 27.7 4.0 1.1 9.8 0.2 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KER26703.1 - 4.1e-05 23.6 0.2 0.00013 21.9 0.2 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_17 PF13431.6 KER26703.1 - 5.6e-05 23.2 0.6 8.5 7.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KER26703.1 - 0.00057 20.0 0.3 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER26703.1 - 0.0018 18.8 7.5 16 6.4 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 KER26703.1 - 0.0019 17.5 0.2 14 4.8 0.0 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat FlaC_arch PF05377.11 KER26703.1 - 0.17 12.3 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ANAPC5 PF12862.7 KER26703.1 - 0.31 11.1 2.0 3.7 7.7 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 PLAC8 PF04749.17 KER26703.1 - 0.62 11.1 4.1 0.66 11.0 0.3 2.5 2 0 0 2 2 2 0 PLAC8 family TPR_10 PF13374.6 KER26703.1 - 1.2 9.1 21.3 4.8 7.2 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat Trypsin PF00089.26 KER26704.1 - 9.5e-08 32.1 0.4 0.0014 18.5 0.4 3.1 2 1 1 3 3 3 2 Trypsin UL21a PF17636.2 KER26704.1 - 0.00067 19.7 2.7 0.69 9.9 0.3 2.3 1 1 1 2 2 2 2 Viral Unique Long protein 21a zf-C2HC_2 PF13913.6 KER26704.1 - 0.039 13.9 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Trypsin PF00089.26 KER26705.1 - 7.1e-48 163.3 0.0 2.1e-34 119.2 0.0 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KER26705.1 - 7.5e-05 23.7 0.0 0.00022 22.1 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Bax1-I PF01027.20 KER26706.1 - 1.9e-27 96.5 26.8 2.6e-27 96.0 26.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RVT_1 PF00078.27 KER26706.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2569 PF10754.9 KER26706.1 - 9.2 6.7 15.2 1.5 9.3 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) BaxI_1 PF12811.7 KER26706.1 - 9.8 5.7 16.9 19 4.7 16.9 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like Kinesin PF00225.23 KER26707.1 - 1.9e-104 349.2 0.0 1.9e-104 349.2 0.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KER26707.1 - 6.5e-22 78.1 0.0 3.6e-21 75.7 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding AAA_24 PF13479.6 KER26707.1 - 0.053 13.2 1.5 35 4.0 0.0 3.8 3 1 0 4 4 4 0 AAA domain CSN5_C PF18323.1 KER26707.1 - 0.13 13.2 0.0 0.13 13.2 0.0 4.9 5 1 1 6 6 6 0 Cop9 signalosome subunit 5 C-terminal domain HALZ PF02183.18 KER26707.1 - 0.24 11.6 8.4 1 9.7 0.2 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper LtuB PF17455.2 KER26707.1 - 1 10.0 8.0 0.68 10.6 0.4 3.5 2 1 1 3 3 3 0 Late transcription unit B Spc42p PF11544.8 KER26707.1 - 1.4 8.9 9.0 0.95 9.5 0.1 5.0 4 1 2 6 6 6 0 Spindle pole body component Spc42p VESA1_N PF12785.7 KER26707.1 - 9.7 5.0 8.6 18 4.1 8.6 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Peptidase_M20 PF01546.28 KER26708.1 - 2.9e-36 125.1 0.2 1.6e-26 93.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KER26708.1 - 4.6e-11 42.6 0.0 7.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KER26708.1 - 0.0061 16.3 0.6 0.1 12.3 0.0 2.8 3 0 0 3 3 3 1 Peptidase family M28 Peptidase_M42 PF05343.14 KER26708.1 - 0.037 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase XFP_C PF09363.10 KER26708.1 - 0.044 13.2 0.1 20 4.6 0.0 3.1 3 0 0 3 3 3 0 XFP C-terminal domain Tenui_NCP PF04876.12 KER26708.1 - 0.11 12.0 0.4 25 4.4 0.0 2.9 3 0 0 3 3 3 0 Tenuivirus major non-capsid protein LANC_like PF05147.13 KER26709.1 - 1.6e-62 211.1 0.0 2.2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 KER26709.1 - 0.11 11.0 0.0 0.7 8.3 0.1 1.8 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Peptidase_M10 PF00413.24 KER26710.1 - 1.1e-49 168.4 0.2 1.5e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 KER26710.1 - 4e-22 77.9 17.7 7.6e-08 32.2 3.1 5.1 4 2 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 KER26710.1 - 9e-07 29.0 0.1 9.6e-06 25.7 0.0 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.6 KER26710.1 - 0.0024 18.4 0.4 0.0044 17.5 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KER26710.1 - 0.012 14.6 0.2 0.021 13.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.6 KER26710.1 - 0.021 15.0 0.3 0.038 14.1 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 KER26710.1 - 0.029 13.0 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 KER26710.1 - 0.24 11.0 0.2 0.42 10.2 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LRR_8 PF13855.6 KER26712.1 - 2.5e-17 62.4 23.5 7.4e-07 28.8 4.1 4.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KER26712.1 - 2.4e-13 50.0 27.0 1.8e-06 28.2 1.7 5.1 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) B3_4 PF03483.17 KER26712.1 - 0.0093 15.7 0.0 0.074 12.7 0.0 2.1 1 1 1 2 2 2 1 B3/4 domain LRR_9 PF14580.6 KER26712.1 - 0.011 15.3 7.0 0.099 12.1 1.1 2.6 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KER26712.1 - 0.068 13.3 13.6 4.2 7.7 0.2 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KER26712.1 - 2.8 8.8 17.6 26 5.9 0.7 7.1 6 3 0 6 6 6 0 Leucine Rich Repeat CLTH PF10607.9 KER26716.1 - 2.6e-10 40.4 0.0 5.6e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KER26716.1 - 0.00084 19.3 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger RVT_1 PF00078.27 KER26716.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Prok-RING_4 PF14447.6 KER26716.1 - 0.1 12.5 1.6 0.29 11.0 1.6 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Tyrosinase PF00264.20 KER26718.1 - 7.4e-16 59.1 0.0 8.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 KER26719.1 - 4.2e-29 102.4 0.3 1.8e-28 100.4 0.3 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF4501 PF14946.6 KER26720.1 - 0.034 14.2 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) F-box_4 PF15966.5 KER26721.1 - 4.6e-29 100.7 0.1 1.1e-28 99.5 0.0 1.6 2 0 0 2 2 2 1 F-box zf-TRAF_2 PF15965.5 KER26721.1 - 4.1e-20 72.0 19.6 3.1e-18 66.0 16.9 2.4 2 0 0 2 2 2 2 TRAF-like zinc-finger zf-TRAF PF02176.18 KER26721.1 - 3.5e-06 27.6 18.9 6.5e-05 23.5 8.5 4.5 3 2 1 4 4 4 2 TRAF-type zinc finger Sina PF03145.16 KER26721.1 - 0.0024 17.9 0.9 0.0045 17.0 0.9 1.4 1 0 0 1 1 1 1 Seven in absentia protein family Prefoldin_2 PF01920.20 KER26723.1 - 1.2e-18 67.0 15.1 1.6e-18 66.6 15.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit YscO PF07321.12 KER26723.1 - 1.6e-05 24.9 17.3 0.00017 21.5 5.2 2.0 1 1 1 2 2 2 2 Type III secretion protein YscO Bcr-Abl_Oligo PF09036.10 KER26723.1 - 4.3e-05 23.4 12.2 0.017 15.1 1.9 2.8 2 1 1 3 3 3 2 Bcr-Abl oncoprotein oligomerisation domain Prefoldin PF02996.17 KER26723.1 - 0.00047 20.1 17.8 0.042 13.8 2.4 3.1 1 1 2 3 3 3 2 Prefoldin subunit KxDL PF10241.9 KER26723.1 - 0.0023 18.1 14.8 0.034 14.4 5.1 2.2 2 1 0 2 2 2 2 Uncharacterized conserved protein FliD_C PF07195.12 KER26723.1 - 0.0031 17.0 6.0 0.0062 16.0 6.0 1.5 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Snapin_Pallidin PF14712.6 KER26723.1 - 0.0032 17.9 14.4 0.11 12.9 3.6 2.6 2 1 0 2 2 2 2 Snapin/Pallidin Spc7 PF08317.11 KER26723.1 - 0.006 15.5 15.7 0.0089 14.9 15.7 1.2 1 1 0 1 1 1 1 Spc7 kinetochore protein RmuC PF02646.16 KER26723.1 - 0.0071 15.5 11.8 0.18 10.9 4.6 2.0 1 1 1 2 2 2 2 RmuC family Snf7 PF03357.21 KER26723.1 - 0.0082 15.8 15.4 0.25 10.9 0.3 2.2 2 0 0 2 2 2 2 Snf7 GCK PF07802.11 KER26723.1 - 0.011 16.1 1.4 0.24 11.9 0.1 2.6 2 1 0 3 3 2 0 GCK domain CALCOCO1 PF07888.11 KER26723.1 - 0.014 14.3 13.2 0.018 14.0 13.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF460 PF04312.13 KER26723.1 - 0.018 14.8 0.4 0.024 14.3 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF460) DUF1664 PF07889.12 KER26723.1 - 0.018 15.1 11.2 0.033 14.2 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ALIX_LYPXL_bnd PF13949.6 KER26723.1 - 0.02 14.2 10.4 0.17 11.1 0.7 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV AAA_13 PF13166.6 KER26723.1 - 0.02 13.6 10.8 0.023 13.4 10.8 1.0 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 KER26723.1 - 0.025 15.0 9.5 0.074 13.5 0.4 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.25 KER26723.1 - 0.026 14.2 11.5 0.6 9.8 11.5 2.1 1 1 0 1 1 1 0 Syntaxin Syntaxin-6_N PF09177.11 KER26723.1 - 0.035 14.7 4.7 0.083 13.5 4.7 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Filo_VP35 PF02097.15 KER26723.1 - 0.04 13.0 0.6 0.075 12.1 0.3 1.5 1 1 0 1 1 1 0 Filoviridae VP35 XhlA PF10779.9 KER26723.1 - 0.041 14.1 2.2 0.041 14.1 2.2 2.6 2 2 1 3 3 3 0 Haemolysin XhlA Tektin PF03148.14 KER26723.1 - 0.044 12.5 16.1 0.1 11.3 1.9 2.1 2 0 0 2 2 2 0 Tektin family RPW8 PF05659.11 KER26723.1 - 0.044 13.5 7.8 2.1 8.0 2.4 2.6 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF812 PF05667.11 KER26723.1 - 0.08 11.8 12.5 0.13 11.1 12.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 KER26723.1 - 0.083 12.6 14.9 0.15 11.8 7.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MutS_IV PF05190.18 KER26723.1 - 0.084 13.2 0.5 0.084 13.2 0.5 3.0 2 1 1 3 3 3 0 MutS family domain IV DUF737 PF05300.11 KER26723.1 - 0.12 12.7 16.2 1.3 9.3 16.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Occludin_ELL PF07303.13 KER26723.1 - 0.13 13.0 11.5 1.2 9.9 6.6 2.3 1 1 1 2 2 2 0 Occludin homology domain DUF4407 PF14362.6 KER26723.1 - 0.13 11.6 10.4 0.2 11.0 10.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MtrB PF05440.12 KER26723.1 - 0.2 12.1 0.2 22 5.6 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2408 PF10303.9 KER26723.1 - 0.22 12.1 9.7 0.33 11.5 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Cluap1 PF10234.9 KER26723.1 - 0.22 10.9 11.9 0.3 10.4 11.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 YabA PF06156.13 KER26723.1 - 0.25 12.0 11.9 2.7 8.7 4.7 2.1 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 KER26723.1 - 0.26 11.6 11.4 0.94 9.8 2.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 KER26723.1 - 0.38 10.8 20.9 1.5 8.9 8.8 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 KER26723.1 - 0.4 10.9 18.8 40 4.4 17.3 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KER26723.1 - 0.4 11.2 17.2 3.1 8.3 17.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KER26723.1 - 0.4 10.7 15.4 0.41 10.7 7.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CK2S PF15011.6 KER26723.1 - 0.43 10.4 10.4 2.3 8.1 10.4 1.9 1 1 0 1 1 1 0 Casein Kinase 2 substrate PspA_IM30 PF04012.12 KER26723.1 - 0.46 10.0 13.3 0.82 9.2 13.3 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF4988 PF16378.5 KER26723.1 - 0.49 10.0 3.7 0.3 10.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF2203 PF09969.9 KER26723.1 - 0.53 11.0 9.4 0.46 11.2 5.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CCDC-167 PF15188.6 KER26723.1 - 0.56 10.6 11.0 1.8 9.0 3.8 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4298 PF14131.6 KER26723.1 - 0.7 9.9 9.1 41 4.2 9.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) PRKG1_interact PF15898.5 KER26723.1 - 0.75 10.7 15.4 59 4.6 15.4 2.4 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Syntaxin_2 PF14523.6 KER26723.1 - 0.76 10.2 13.4 0.33 11.3 4.8 2.2 1 1 1 2 2 2 0 Syntaxin-like protein Phage_GP20 PF06810.11 KER26723.1 - 0.77 9.6 13.4 0.17 11.7 6.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Rx_N PF18052.1 KER26723.1 - 0.83 10.0 9.2 0.82 10.0 2.5 2.6 1 1 1 2 2 2 0 Rx N-terminal domain WXG100 PF06013.12 KER26723.1 - 0.85 9.9 7.6 15 5.9 1.6 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG THOC7 PF05615.13 KER26723.1 - 0.88 9.8 20.1 1.3 9.3 2.0 3.0 2 1 1 3 3 3 0 Tho complex subunit 7 COG2 PF06148.11 KER26723.1 - 0.96 9.5 10.1 4.2 7.5 2.1 2.7 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4446 PF14584.6 KER26723.1 - 1.2 9.2 10.4 1.2 9.2 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) JIP_LZII PF16471.5 KER26723.1 - 1.2 9.4 13.8 0.24 11.6 2.9 3.0 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Fib_alpha PF08702.10 KER26723.1 - 1.2 9.3 13.6 14 5.9 13.6 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 KER26723.1 - 1.3 8.8 12.7 0.48 10.2 8.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KER26723.1 - 1.3 9.2 17.3 1.6 9.0 7.6 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DLP_helical PF18709.1 KER26723.1 - 1.3 8.1 12.7 0.33 10.1 4.3 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain HemX PF04375.14 KER26723.1 - 1.4 8.1 14.4 5.4 6.2 14.4 1.8 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3734 PF12536.8 KER26723.1 - 1.4 9.3 7.0 8.5 6.8 1.2 2.2 2 0 0 2 2 2 0 Patatin phospholipase Spc24 PF08286.11 KER26723.1 - 1.5 9.1 13.6 2 8.7 3.6 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CLZ PF16526.5 KER26723.1 - 1.5 9.2 11.2 2.3 8.7 2.0 3.0 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4404 PF14357.6 KER26723.1 - 1.5 9.5 11.4 3 8.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CREPT PF16566.5 KER26723.1 - 1.6 8.9 14.0 0.74 10.0 2.3 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ABC_tran_CTD PF16326.5 KER26723.1 - 1.9 8.8 13.3 2.2 8.6 5.9 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4140 PF13600.6 KER26723.1 - 1.9 9.0 10.7 0.57 10.7 2.8 2.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 KER26723.1 - 2.2 7.5 13.0 1.1 8.5 6.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF3450 PF11932.8 KER26723.1 - 2.3 7.5 17.5 0.78 9.0 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Plk4_PB2 PF18409.1 KER26723.1 - 2.4 8.9 8.9 3.4 8.4 1.8 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF2721 PF11026.8 KER26723.1 - 2.5 8.0 4.7 2.1 8.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Nup88 PF10168.9 KER26723.1 - 2.8 5.6 14.4 3.5 5.3 14.4 1.1 1 0 0 1 1 1 0 Nuclear pore component DMPK_coil PF08826.10 KER26723.1 - 2.9 8.1 16.3 0.81 9.9 3.0 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like V_ATPase_I PF01496.19 KER26723.1 - 2.9 5.7 7.8 3.7 5.4 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 KER26723.1 - 3 7.9 20.0 0.78 9.8 7.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 KER26723.1 - 3.2 7.8 15.5 4.7 7.3 15.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMP24_GP25L PF01105.24 KER26723.1 - 3.9 7.4 11.4 0.41 10.6 2.6 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1690 PF07956.11 KER26723.1 - 4.1 7.8 14.4 3.6e+02 1.5 14.4 2.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Rho_Binding PF08912.11 KER26723.1 - 4.3 8.2 14.8 3.2 8.6 5.4 2.4 2 1 0 2 2 2 0 Rho Binding FliD_N PF02465.18 KER26723.1 - 5.2 7.8 8.8 15 6.3 1.6 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus LMBR1 PF04791.16 KER26723.1 - 5.8 5.7 10.6 4.9 5.9 2.7 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 KER26723.1 - 6.4 6.3 11.9 2.9 7.4 3.2 2.2 1 1 0 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.15 KER26723.1 - 6.5 6.2 12.7 9.7 5.7 12.7 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit GTP-bdg_M PF16360.5 KER26723.1 - 6.8 7.4 13.4 2.4 8.8 1.7 3.1 1 1 2 3 3 3 0 GTP-binding GTPase Middle Region Swi5 PF07061.11 KER26723.1 - 6.9 6.8 13.7 6.9e+03 -2.8 13.7 2.8 1 1 0 1 1 0 0 Swi5 DUF16 PF01519.16 KER26723.1 - 7.2 7.2 15.6 0.38 11.3 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KER26723.1 - 8.3 7.1 13.7 7.2 7.3 5.0 2.7 2 1 0 2 2 2 0 SlyX Herpes_UL6 PF01763.16 KER26723.1 - 9.2 4.6 12.7 1.3 7.4 3.5 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like DRMBL PF07522.14 KER26724.1 - 4.3e-05 23.6 0.0 0.00023 21.3 0.0 2.1 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 KER26724.1 - 0.00034 20.5 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain RhoGEF PF00621.20 KER26726.1 - 2.1e-25 90.0 2.0 4e-25 89.1 0.4 2.2 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 KER26726.1 - 5.5e-12 45.8 0.1 1.3e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER26726.1 - 0.00067 20.1 0.4 0.0082 16.6 0.0 3.0 3 1 0 3 3 3 1 PH domain IQ_SEC7_PH PF16453.5 KER26726.1 - 0.0063 16.5 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 KER26726.1 - 0.011 15.9 5.8 0.019 15.0 0.2 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain PH_16 PF17838.1 KER26726.1 - 0.017 15.0 0.1 0.25 11.2 0.1 2.3 1 1 0 1 1 1 0 PH domain Borrelia_REV PF03978.13 KER26726.1 - 0.067 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein RVT_1 PF00078.27 KER26729.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_12 PF13424.6 KER26730.1 - 6.8e-13 48.7 8.4 2.8e-10 40.3 0.8 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER26730.1 - 5.1e-10 38.8 7.7 0.0014 18.3 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER26730.1 - 3.5e-09 36.1 8.1 0.0005 20.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER26730.1 - 1.6e-08 34.1 7.2 0.00047 20.1 0.1 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER26730.1 - 3.4e-05 23.9 1.7 1.8 8.8 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER26730.1 - 9.3e-05 23.0 0.9 0.2 12.3 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER26730.1 - 0.00011 22.0 14.2 0.00068 19.4 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER26730.1 - 0.0006 19.7 9.4 0.3 11.2 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER26730.1 - 0.014 15.9 0.7 0.066 13.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER26730.1 - 0.03 14.0 3.6 1.8 8.3 0.0 4.1 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 KER26730.1 - 0.069 14.0 7.8 24 6.1 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER26730.1 - 0.081 13.6 9.6 9.5 7.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KER26730.1 - 0.77 9.9 5.1 5.6 7.1 0.2 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 KER26730.1 - 5.1 7.7 5.2 3.6 8.2 0.0 3.5 4 1 1 5 5 3 0 Tetratricopeptide repeat UBN_AB PF14075.6 KER26731.1 - 6.3e-45 153.5 0.0 1.3e-44 152.5 0.0 1.6 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 KER26731.1 - 3.3e-17 62.2 0.7 6e-17 61.4 0.7 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF1871 PF08958.10 KER26733.1 - 0.087 13.2 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) PknG_rubred PF16919.5 KER26733.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Pkinase PF00069.25 KER26734.1 - 3.2e-34 118.5 0.0 1.6e-33 116.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26734.1 - 1.9e-18 66.7 0.0 2.9e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER26734.1 - 0.0016 17.8 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER26734.1 - 0.053 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KER26734.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.17 KER26735.1 - 6.3e-72 242.0 0.3 2.8e-69 233.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER26735.1 - 5.8e-34 117.6 0.3 1.3e-33 116.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KER26735.1 - 1.7e-19 69.6 0.0 1.6e-16 60.2 0.0 2.8 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.28 KER26735.1 - 1.1e-11 44.1 0.1 2.6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER26735.1 - 2.8e-11 43.1 0.3 2.5e-10 40.0 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KER26735.1 - 1.2e-08 34.5 0.1 2.6e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KER26735.1 - 1.7e-06 28.5 0.3 6.4e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 PH domain BTK PF00779.19 KER26735.1 - 3.5e-05 23.5 0.9 3.5e-05 23.5 0.9 1.9 2 0 0 2 2 2 1 BTK motif hSH3 PF14603.6 KER26735.1 - 0.0021 18.5 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 Helically-extended SH3 domain Pertussis_S1 PF02917.14 KER26735.1 - 0.0035 17.2 0.1 0.0069 16.2 0.1 1.4 1 0 0 1 1 1 1 Pertussis toxin, subunit 1 Kdo PF06293.14 KER26735.1 - 0.0036 16.7 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_10 PF17902.1 KER26735.1 - 0.026 14.6 0.2 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 SH3 domain Haspin_kinase PF12330.8 KER26735.1 - 0.079 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain SH3_3 PF08239.11 KER26735.1 - 0.083 13.2 1.5 0.2 11.9 1.5 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Glyco_hydro_56 PF01630.18 KER26736.1 - 0.036 13.1 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Hyaluronidase CBM_4_9 PF02018.17 KER26737.1 - 0.046 14.0 0.1 0.056 13.7 0.1 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain DnaJ PF00226.31 KER26739.1 - 4.1e-18 65.3 0.1 6.5e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L30 PF00327.20 KER26740.1 - 0.00039 20.3 0.2 0.00065 19.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FAR1 PF03101.15 KER26740.1 - 0.017 15.8 0.1 0.039 14.7 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF5575 PF17738.1 KER26740.1 - 0.24 10.4 2.5 1.8 7.5 2.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5575) Peptidase_M28 PF04389.17 KER26742.1 - 9.8e-36 123.3 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ParA PF10609.9 KER26744.1 - 7.6e-90 300.7 0.0 9e-90 300.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KER26744.1 - 8.1e-09 35.6 0.0 4.7e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KER26744.1 - 3.8e-06 26.3 2.0 0.00014 21.1 1.0 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KER26744.1 - 1.1e-05 24.8 0.3 6e-05 22.5 0.1 2.3 2 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KER26744.1 - 2.6e-05 24.2 0.2 0.00014 21.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 KER26744.1 - 0.0033 17.3 0.3 1.2 8.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KER26744.1 - 0.0078 15.8 0.5 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KER26744.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 KER26744.1 - 0.01 14.9 0.6 0.015 14.2 0.6 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KER26744.1 - 0.021 14.0 0.9 0.036 13.3 0.9 1.3 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 KER26744.1 - 0.043 13.6 0.1 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 KER26744.1 - 0.093 13.3 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KER26744.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 KER26744.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4911 PF16256.5 KER26744.1 - 0.16 12.0 0.1 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) NACHT PF05729.12 KER26744.1 - 0.17 11.8 1.6 0.2 11.5 0.6 1.7 2 0 0 2 2 1 0 NACHT domain NTPase_1 PF03266.15 KER26744.1 - 0.22 11.4 0.3 0.39 10.6 0.3 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KER26744.1 - 0.24 11.1 0.1 0.45 10.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KER26744.1 - 0.38 10.7 1.4 0.98 9.3 1.4 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KER26744.1 - 0.74 10.2 3.0 0.55 10.6 1.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Clat_adaptor_s PF01217.20 KER26745.1 - 2.8e-95 315.8 7.6 2.5e-56 189.6 1.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain CNOT1_HEAT PF16418.5 KER26745.1 - 0.0016 18.6 0.4 1.7 8.7 0.1 2.3 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4508 PF14969.6 KER26745.1 - 0.0018 18.5 1.5 1.7 9.0 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) DUF4422 PF14393.6 KER26745.1 - 0.0046 16.8 0.6 0.16 11.8 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4422) FAD_SOX PF18371.1 KER26745.1 - 0.0085 16.4 0.7 14 6.1 0.0 3.5 4 0 0 4 4 4 1 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase KaiA PF07688.12 KER26745.1 - 0.041 14.0 7.0 2.3 8.4 0.1 3.5 3 1 1 4 4 4 0 KaiA C-terminal domain DUF2057 PF09829.9 KER26745.1 - 0.045 13.9 2.6 3.1 7.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) AftA_C PF12249.8 KER26745.1 - 0.11 12.1 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 Arabinofuranosyltransferase A C terminal Arm_3 PF16186.5 KER26745.1 - 0.2 11.2 2.0 6.4 6.4 0.1 3.3 3 2 0 3 3 3 0 Atypical Arm repeat Sema PF01403.19 KER26746.1 - 2.6e-40 138.6 0.1 4.4e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 KER26746.1 - 1.4e-08 34.8 86.4 0.0018 18.4 10.3 10.0 8 1 0 8 8 8 6 Thrombospondin type 1 domain Sema PF01403.19 KER26747.1 - 0.0014 17.6 0.0 0.0017 17.3 0.0 1.4 1 1 0 1 1 1 1 Sema domain Strep_pep PF14404.6 KER26747.1 - 0.0064 16.7 0.2 6.1 7.2 0.0 2.6 2 1 0 2 2 2 2 Ribosomally synthesized peptide in Streptomyces species DNA_pol_E_B PF04042.16 KER26749.1 - 5.7e-14 52.0 0.0 7.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.7 KER26749.1 - 0.035 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NPFF PF15085.6 KER26751.1 - 0.062 13.7 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 Neuropeptide FF ECH_1 PF00378.20 KER26752.1 - 2.6e-27 95.7 0.2 3.9e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MJ1316 PF04457.12 KER26752.1 - 3.3e-24 85.4 0.1 9.8e-24 83.9 0.1 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain AKAP7_NLS PF10469.9 KER26752.1 - 1.3e-23 83.9 0.0 2.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain ECH_2 PF16113.5 KER26752.1 - 3.8e-13 49.6 0.1 2.1e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase 2_5_RNA_ligase2 PF13563.6 KER26752.1 - 8e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KER26752.1 - 1.3e-05 25.3 0.0 0.042 14.0 0.0 2.9 2 0 0 2 2 2 2 LigT like Phosphoesterase PALP PF00291.25 KER26753.1 - 2.3e-61 207.8 0.1 3.4e-61 207.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RRM_1 PF00076.22 KER26753.1 - 1.7e-21 75.8 0.0 8.8e-16 57.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KER26753.1 - 0.00036 20.5 0.1 0.014 15.4 0.0 2.7 3 0 0 3 3 3 1 RNA binding domain RRM_7 PF16367.5 KER26753.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 14-3-3 PF00244.20 KER26755.1 - 8.1e-10 38.6 0.4 1.1e-09 38.2 0.3 1.3 1 1 0 1 1 1 1 14-3-3 protein DnaJ PF00226.31 KER26756.1 - 1e-21 76.8 1.0 1e-21 76.8 1.0 2.6 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.6 KER26756.1 - 1.3e-19 70.4 10.9 0.00015 22.2 0.4 6.5 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER26756.1 - 4.6e-19 66.9 6.0 0.0075 16.3 0.0 9.1 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER26756.1 - 1.8e-16 60.5 7.9 6.6e-06 26.7 1.1 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER26756.1 - 1.4e-13 50.0 1.9 0.00046 19.9 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER26756.1 - 7.6e-12 45.0 11.5 0.18 12.7 0.4 8.2 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER26756.1 - 5.5e-11 41.8 0.1 2.2 8.7 0.0 7.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER26756.1 - 3.1e-10 40.1 9.2 0.052 13.7 0.2 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER26756.1 - 5.1e-10 39.0 0.0 0.0059 16.9 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KER26756.1 - 6.9e-10 39.0 7.0 0.034 14.4 1.2 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KER26756.1 - 1.4e-06 27.8 0.7 0.00012 21.7 0.1 4.2 5 0 0 5 5 5 1 TPR repeat Alkyl_sulf_dimr PF14863.6 KER26756.1 - 1.9e-05 25.2 3.7 0.45 11.0 0.0 4.3 3 1 0 4 4 4 1 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KER26756.1 - 5.2e-05 23.6 15.5 9 7.2 0.1 9.9 10 2 1 11 11 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KER26756.1 - 0.00043 20.6 7.0 0.0041 17.4 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER26756.1 - 0.00057 20.1 11.6 13 6.2 0.0 6.3 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER26756.1 - 0.031 14.3 7.2 5.2 7.3 0.2 6.0 7 2 0 7 7 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER26756.1 - 0.049 13.1 1.4 30 4.2 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR ANAPC5 PF12862.7 KER26756.1 - 0.05 13.7 1.3 6.3 6.9 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 HrpB1_HrpK PF09613.10 KER26756.1 - 0.072 12.7 0.6 1.6 8.4 0.0 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4363 PF14276.6 KER26756.1 - 0.082 13.0 1.3 2.8 8.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF982 PF06169.12 KER26756.1 - 0.082 13.0 0.5 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF982) FRB_dom PF08771.11 KER26756.1 - 0.087 13.2 2.9 7 7.1 0.2 3.3 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain YfdX PF10938.8 KER26756.1 - 0.49 10.3 4.1 8.6 6.3 0.1 3.3 4 0 0 4 4 3 0 YfdX protein FlbT PF07378.11 KER26756.1 - 0.8 9.8 3.5 4.1 7.5 0.7 2.6 2 0 0 2 2 2 0 Flagellar protein FlbT RVT_1 PF00078.27 KER26759.1 - 4.4e-08 32.9 0.0 6.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 KER26760.1 - 8.5e-19 68.4 0.0 1.2e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER26760.1 - 0.00091 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Hairy_orange PF07527.13 KER26760.1 - 0.064 13.5 0.3 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Hairy Orange DNA_pol_phi PF04931.13 KER26762.1 - 0.0026 16.0 33.9 0.0026 16.0 33.9 3.1 2 1 0 2 2 2 1 DNA polymerase phi BUD22 PF09073.10 KER26762.1 - 1.1 8.6 64.6 0.17 11.2 19.5 2.3 2 0 0 2 2 2 0 BUD22 SH3_4 PF06347.13 KER26765.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RhoGAP PF00620.27 KER26766.1 - 1.3e-21 77.1 0.0 6.7e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain TRAM_LAG1_CLN8 PF03798.16 KER26771.1 - 6.5e-18 65.2 25.8 7.7e-18 65.0 25.8 1.0 1 0 0 1 1 1 1 TLC domain DUF4293 PF14126.6 KER26771.1 - 0.55 10.5 8.5 0.038 14.2 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Ank_2 PF12796.7 KER26773.1 - 5.8e-77 254.3 4.1 2.6e-14 53.6 0.1 8.9 3 2 6 9 9 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER26773.1 - 8.6e-66 217.5 11.9 3.7e-09 36.9 0.0 11.1 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER26773.1 - 5.9e-54 179.4 23.8 9.5e-08 32.2 0.1 10.7 6 3 6 12 12 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KER26773.1 - 7.5e-53 174.8 23.5 0.00074 19.9 0.0 15.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.6 KER26773.1 - 1.4e-38 126.5 20.7 0.28 11.9 0.0 16.4 16 0 0 16 16 16 10 Ankyrin repeat NACHT PF05729.12 KER26773.1 - 0.00023 21.1 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KER26773.1 - 0.00055 20.2 0.0 0.0024 18.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KER26773.1 - 0.0018 18.6 0.1 0.0041 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER26773.1 - 0.002 18.5 0.2 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KER26773.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KER26773.1 - 0.027 14.7 0.1 0.087 13.0 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 KER26773.1 - 0.036 14.5 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER26773.1 - 0.043 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KER26773.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KER26773.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase FUR PF01475.19 KER26773.1 - 0.1 12.7 0.1 1.1 9.5 0.2 2.3 2 0 0 2 2 2 0 Ferric uptake regulator family ABC_tran PF00005.27 KER26773.1 - 0.12 12.9 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KER26773.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KER26773.1 - 0.13 11.4 0.2 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KER26773.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KER26773.1 - 0.25 11.3 0.1 0.49 10.3 0.1 1.5 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 KER26773.1 - 1 9.0 4.0 0.32 10.7 0.1 2.1 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Band_7 PF01145.25 KER26775.1 - 6.7e-15 55.5 0.1 6.7e-15 55.5 0.1 3.1 3 1 0 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 KER26775.1 - 7.2e-09 35.9 4.6 7.2e-09 35.9 4.6 3.9 2 2 2 4 4 4 3 Flotillin MULE PF10551.9 KER26777.1 - 4.9e-30 103.8 7.6 9.2e-19 67.7 0.0 4.4 5 0 0 5 5 5 2 MULE transposase domain Rep_fac_C PF08542.11 KER26777.1 - 1.6e-14 54.0 0.1 4.3e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain SWIM PF04434.17 KER26777.1 - 1.5e-13 50.1 12.3 0.00099 18.7 0.5 3.7 3 0 0 3 3 3 3 SWIM zinc finger AAA PF00004.29 KER26777.1 - 1.9e-11 44.5 0.0 3.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KER26777.1 - 4.3e-11 42.9 0.1 5.2e-10 39.3 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit FAR1 PF03101.15 KER26777.1 - 4.7e-09 36.8 6.7 0.0011 19.6 0.5 2.8 2 0 0 2 2 2 2 FAR1 DNA-binding domain Viral_helicase1 PF01443.18 KER26777.1 - 2.9e-06 27.2 0.0 6.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KER26777.1 - 1e-05 25.6 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KER26777.1 - 0.00019 21.4 0.0 0.00047 20.1 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KER26777.1 - 0.00039 20.9 0.0 0.0075 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Transposase_mut PF00872.18 KER26777.1 - 0.00078 18.4 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family AAA_22 PF13401.6 KER26777.1 - 0.0015 18.8 0.1 0.18 12.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KER26777.1 - 0.0037 17.1 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KER26777.1 - 0.0083 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PHD PF00628.29 KER26777.1 - 0.01 15.7 1.0 0.043 13.7 1.0 2.1 1 0 0 1 1 1 1 PHD-finger AAA_24 PF13479.6 KER26777.1 - 0.016 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KER26777.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 KER26777.1 - 0.025 14.9 0.1 0.13 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KER26777.1 - 0.027 15.0 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KER26777.1 - 0.053 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KER26777.1 - 0.075 12.4 0.0 0.24 10.7 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KER26777.1 - 0.082 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KER26777.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain zf-ribbon_3 PF13248.6 KER26777.1 - 6.5 6.3 7.4 21 4.7 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Ribonuc_red_lgN PF00317.21 KER26779.1 - 4.9e-14 52.1 0.1 7.7e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_lgC PF02867.15 KER26779.1 - 3e-06 26.0 0.1 4.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain HSP70 PF00012.20 KER26780.1 - 3.6e-264 877.5 10.4 4.1e-264 877.3 10.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER26780.1 - 4.1e-18 65.3 0.4 1.3e-16 60.4 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KER26780.1 - 0.00038 20.8 1.1 1.5 9.3 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KER26780.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MetOD2 PF18548.1 KER26780.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.4 3 1 2 5 5 5 0 Metanogen output domain 2 Cnd1_N PF12922.7 KER26780.1 - 0.14 12.0 1.3 0.28 11.0 1.3 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PIN_8 PF18476.1 KER26780.1 - 1.8 8.4 9.3 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 PIN like domain HSP70 PF00012.20 KER26782.1 - 4.6e-262 870.6 10.8 5.2e-262 870.4 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER26782.1 - 1.6e-17 63.3 0.5 3.6e-16 58.9 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KER26782.1 - 0.00043 20.7 1.8 1.5 9.3 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KER26782.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MetOD2 PF18548.1 KER26782.1 - 0.038 14.1 0.9 0.15 12.2 0.1 2.4 2 0 0 2 2 2 0 Metanogen output domain 2 Cnd1_N PF12922.7 KER26782.1 - 0.17 11.7 1.3 0.34 10.8 1.3 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Spore_GerAC PF05504.11 KER26782.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.1 3 1 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal PIN_8 PF18476.1 KER26782.1 - 0.64 9.8 8.1 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 PIN like domain HSP70 PF00012.20 KER26783.1 - 2.4e-264 878.1 11.9 2.7e-264 877.9 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER26783.1 - 1.3e-16 60.3 0.7 5.1e-15 55.1 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KER26783.1 - 0.0042 16.8 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KER26783.1 - 0.0087 15.1 0.3 0.075 12.0 0.2 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 KER26783.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) FtsA PF14450.6 KER26783.1 - 0.019 15.4 5.5 3.6 8.0 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KER26783.1 - 0.025 14.1 0.1 6.4 6.2 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MetOD2 PF18548.1 KER26783.1 - 1 9.5 6.4 0.47 10.6 0.1 2.7 2 1 0 2 2 2 0 Metanogen output domain 2 PIN_8 PF18476.1 KER26783.1 - 1.6 8.6 8.0 0.53 10.1 0.2 2.4 2 0 0 2 2 2 0 PIN like domain HSP70 PF00012.20 KER26785.1 - 3.5e-273 907.3 9.9 2.8e-172 574.0 1.8 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KER26785.1 - 4.5e-21 75.0 0.3 2e-10 40.0 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein DDR PF08841.10 KER26785.1 - 0.0001 21.4 0.4 0.34 9.9 0.0 3.1 2 1 1 3 3 3 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KER26785.1 - 0.00034 20.0 1.6 0.68 9.1 0.1 3.1 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KER26785.1 - 0.0015 18.1 0.4 3.1 7.2 0.0 3.1 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KER26785.1 - 0.0029 18.0 4.4 2.2 8.7 0.0 4.2 4 2 0 4 4 4 2 Cell division protein FtsA StbA PF06406.11 KER26785.1 - 0.004 16.4 0.3 0.94 8.7 0.1 2.5 1 1 0 2 2 2 2 StbA protein FGGY_C PF02782.16 KER26785.1 - 0.042 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1542 PF07564.11 KER26785.1 - 0.22 11.7 3.3 0.3 11.2 0.4 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glyco_hydro_19 PF00182.19 KER26787.1 - 7.9e-20 71.7 0.5 3.5e-18 66.4 0.5 2.6 1 1 0 1 1 1 1 Chitinase class I Sulfotransfer_3 PF13469.6 KER26788.1 - 6e-39 134.7 0.0 1e-38 133.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER26788.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KER26788.1 - 0.042 13.7 0.0 0.19 11.5 0.0 2.3 1 1 0 1 1 1 0 Sulfotransferase domain IMD PF08397.11 KER26791.1 - 1.9e-32 112.5 0.2 3.5e-30 105.0 0.2 2.2 1 1 0 1 1 1 1 IRSp53/MIM homology domain Tubulin PF00091.25 KER26795.1 - 2.2e-54 184.7 0.0 4.4e-54 183.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER26795.1 - 9.8e-33 113.0 1.8 1.5e-32 112.4 0.2 2.2 2 0 0 2 2 2 1 Tubulin C-terminal domain Eclosion PF04736.12 KER26797.1 - 0.0079 15.9 0.8 2.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Eclosion hormone Proteasome PF00227.26 KER26798.1 - 6.3e-11 42.1 0.0 7.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit CD52 PF15116.6 KER26798.1 - 0.061 13.4 0.8 0.11 12.6 0.8 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen CDC37_M PF08565.11 KER26800.1 - 8.2e-23 80.6 2.1 9.9e-23 80.3 0.1 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KER26800.1 - 4.4e-15 55.6 0.0 4.4e-15 55.6 0.0 2.3 2 1 0 2 2 2 1 Cdc37 C terminal domain CDC37_N PF03234.14 KER26800.1 - 2.4e-08 34.9 1.8 2.4e-08 34.9 1.8 2.1 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding FliD_C PF07195.12 KER26800.1 - 0.083 12.3 3.4 5.6 6.3 1.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UBM PF14377.6 KER26800.1 - 0.1 12.1 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin binding region Syndecan PF01034.20 KER26801.1 - 0.28 11.1 0.2 0.63 10.0 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Tom37 PF10568.9 KER26802.1 - 1.2e-20 74.1 0.0 8.2e-17 61.7 0.0 2.4 1 1 1 2 2 2 2 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KER26802.1 - 6.5e-15 54.7 1.2 1.7e-13 50.2 1.2 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KER26802.1 - 7e-09 36.3 0.0 5e-08 33.6 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KER26802.1 - 0.00055 19.9 0.2 0.0015 18.5 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.22 KER26803.1 - 0.01 15.5 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HIM1 PF08732.10 KER26803.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 HIM1 Pkinase PF00069.25 KER26806.1 - 2.6e-63 213.8 0.0 5.1e-58 196.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER26806.1 - 4.8e-29 101.4 0.0 9.8e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER26806.1 - 4.8e-05 22.8 0.1 0.00017 21.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KER26806.1 - 0.002 17.2 0.1 0.0039 16.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER26806.1 - 0.036 13.4 0.2 0.083 12.2 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 KER26807.1 - 1.8e-20 72.5 0.2 8.8e-13 47.9 0.2 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps4_C PF09336.10 KER26807.1 - 0.0055 16.7 0.1 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_pol_Rpb1_3 PF04983.18 KER26807.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 F-box PF00646.33 KER26809.1 - 0.00021 21.1 0.2 0.00075 19.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KER26809.1 - 0.00081 19.2 0.8 0.0028 17.5 0.8 1.9 1 0 0 1 1 1 1 F-box-like DUF3908 PF13048.6 KER26809.1 - 0.21 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) zf-met PF12874.7 KER26812.1 - 1.2e-06 28.7 3.7 0.028 14.8 1.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER26812.1 - 1.9e-06 28.2 8.8 0.00027 21.5 1.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER26812.1 - 1.4e-05 25.3 0.3 1.4e-05 25.3 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KER26812.1 - 0.0011 19.3 12.3 0.023 15.1 1.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KER26812.1 - 0.0035 17.6 1.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KER26812.1 - 0.093 13.1 3.6 0.85 10.0 0.3 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KER26812.1 - 0.14 12.7 0.6 0.34 11.4 0.6 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KER26812.1 - 0.14 12.2 7.8 0.095 12.7 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER26812.1 - 0.55 10.6 4.2 1.2 9.5 4.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KER26812.1 - 0.93 9.6 8.7 0.16 12.0 1.7 2.4 1 1 1 2 2 2 0 BED zinc finger BK_channel_a PF03493.18 KER26815.1 - 1.1e-28 99.3 0.0 7e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 KER26815.1 - 3.2e-19 69.1 14.4 6e-19 68.2 14.4 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER26815.1 - 1.5e-14 53.7 9.5 3.4e-14 52.6 6.6 2.7 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 KER26815.1 - 0.028 14.7 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RT_RNaseH_2 PF17919.1 KER26819.1 - 0.031 14.3 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase PFK PF00365.20 KER26820.1 - 1.3e-199 661.2 1.3 3.5e-108 361.3 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase Ank_2 PF12796.7 KER26822.1 - 8.4e-169 548.6 51.5 1.1e-16 61.1 0.5 14.3 2 1 12 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER26822.1 - 5.9e-152 492.3 53.2 3.3e-13 49.8 0.4 19.5 7 5 16 23 23 23 23 Ankyrin repeats (many copies) Ank PF00023.30 KER26822.1 - 1.3e-148 477.6 86.7 2.9e-07 30.6 0.2 26.8 26 1 1 27 27 27 24 Ankyrin repeat Ank_5 PF13857.6 KER26822.1 - 1.3e-135 439.7 57.6 3e-12 46.5 0.0 21.9 5 5 19 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER26822.1 - 9.6e-125 391.2 56.3 5.1e-05 23.4 0.0 27.5 28 0 0 28 28 28 23 Ankyrin repeat UPA_2 PF17809.1 KER26822.1 - 7.5e-45 152.0 0.0 2e-44 150.6 0.0 1.8 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 KER26822.1 - 2.2e-35 120.9 0.3 3.5e-26 91.4 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 KER26822.1 - 4.1e-05 23.6 0.3 0.00012 22.2 0.1 1.9 2 0 0 2 2 2 1 Death domain DUF2384 PF09722.10 KER26822.1 - 0.13 12.3 0.6 1e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) ProRS-C_1 PF09180.11 KER26824.1 - 0.02 15.1 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Acyl_transf_3 PF01757.22 KER26826.1 - 3.8e-08 32.8 48.0 8.2e-07 28.4 13.4 2.6 2 1 1 3 3 3 2 Acyltransferase family Acyl_transf_3 PF01757.22 KER26827.1 - 0.065 12.3 41.2 0.047 12.7 15.7 3.3 2 1 1 3 3 3 0 Acyltransferase family Ribosomal_L14e PF01929.17 KER26828.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L14 Mito_carr PF00153.27 KER26829.1 - 3.1e-47 158.4 0.4 1e-15 57.4 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein V_cholerae_RfbT PF05575.11 KER26831.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein HoxA13_N PF12284.8 KER26832.1 - 0.024 15.3 3.5 0.056 14.1 0.5 2.3 2 0 0 2 2 2 0 Hox protein A13 N terminal DUF2052 PF09747.9 KER26833.1 - 0.18 11.9 3.7 0.29 11.2 3.7 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF778 PF05608.12 KER26837.1 - 5.2e-34 118.3 3.3 3.4e-19 70.0 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 KER26837.1 - 0.016 14.9 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Herpes_U34 PF04541.13 KER26838.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus virion protein U34 Methyltr_RsmB-F PF01189.17 KER26840.1 - 2.2e-30 105.8 0.0 4.3e-23 82.0 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KER26840.1 - 0.0046 17.1 0.1 0.01 16.0 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase EMP24_GP25L PF01105.24 KER26840.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD STN1_2 PF09170.10 KER26840.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Ldh_2 PF02615.14 KER26842.1 - 3.2e-62 210.6 0.1 3.7e-62 210.4 0.1 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Abhydrolase_3 PF07859.13 KER26845.1 - 0.028 14.3 1.4 0.075 12.9 1.4 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold GTP_EFTU PF00009.27 KER26847.1 - 1.3e-26 93.3 0.1 2.4e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER26847.1 - 9.3e-08 32.1 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KER26847.1 - 1.6e-06 28.4 0.0 4.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KER26847.1 - 0.00017 21.1 0.3 0.00078 18.9 0.3 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KER26847.1 - 0.035 13.3 0.4 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KER26847.1 - 0.073 12.8 0.5 4 7.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KER26847.1 - 0.094 12.5 2.1 6.2 6.5 0.3 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF5522 PF17653.1 KER26849.1 - 2e-24 85.2 5.1 3e-24 84.7 5.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peptidase_S8 PF00082.22 KER26850.1 - 3.8e-40 138.0 3.2 4.9e-40 137.6 3.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KER26850.1 - 2.4e-22 78.8 0.1 5e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KER26850.1 - 1e-12 48.7 0.3 2.1e-12 47.6 0.3 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain COPIIcoated_ERV PF07970.12 KER26852.1 - 9.4e-41 140.1 0.0 1.3e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KER26852.1 - 8.4e-25 87.0 0.3 1.9e-24 85.8 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SH2 PF00017.24 KER26855.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Peptidase_M48 PF01435.18 KER26857.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M48 EMC1_C PF07774.13 KER26860.1 - 4.3e-61 206.3 0.4 4e-60 203.1 0.4 2.3 1 1 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KER26860.1 - 0.0001 22.0 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KER26860.1 - 0.13 12.2 0.0 61 3.8 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Ephrin_rec_like PF07699.13 KER26861.1 - 1.2e-09 37.8 8.6 1.2e-09 37.8 8.6 3.2 4 0 0 4 4 4 2 Putative ephrin-receptor like NCD3G PF07562.14 KER26861.1 - 0.00058 19.8 6.4 0.00099 19.0 5.4 2.0 1 1 1 2 2 2 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 KER26861.1 - 0.18 12.2 10.5 0.66 10.4 2.1 2.8 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region zf-C2H2_6 PF13912.6 KER26862.1 - 0.00059 19.8 0.7 0.0018 18.2 0.7 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KER26862.1 - 0.00083 19.7 1.0 0.00083 19.7 1.0 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KER26862.1 - 0.0015 18.9 0.4 0.0088 16.4 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER26862.1 - 0.0015 19.2 2.7 0.0058 17.4 0.3 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER26862.1 - 0.0024 18.1 1.3 0.011 16.0 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KER26862.1 - 0.0039 17.6 3.0 1.5 9.3 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER26865.1 - 3.9e-17 61.7 20.8 0.00033 21.0 0.2 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER26865.1 - 9.6e-12 44.7 18.6 0.026 15.3 0.3 5.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER26865.1 - 1.4e-11 44.3 29.6 3e-06 27.4 0.2 6.0 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KER26865.1 - 0.017 15.2 1.6 6.9 6.8 0.0 3.1 2 1 1 3 3 3 0 Aberrant zinc-finger Raffinose_syn PF05691.12 KER26865.1 - 0.07 10.9 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_6 PF13912.6 KER26865.1 - 0.29 11.2 14.9 3.5 7.7 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KER26865.1 - 0.36 11.5 2.6 12 6.6 0.1 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 KER26865.1 - 0.55 11.0 7.3 16 6.3 0.7 3.6 2 1 0 3 3 3 0 CHORD IBR PF01485.21 KER26865.1 - 1.1 9.6 9.5 0.71 10.1 3.2 2.7 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KER26865.1 - 1.5 9.2 7.8 33 4.9 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.8 KER26865.1 - 1.8 8.5 5.1 22 5.0 0.3 3.7 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_11 PF16622.5 KER26865.1 - 9.8 6.0 10.9 13 5.7 0.3 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type bZIP_2 PF07716.15 KER26868.1 - 4.7e-11 42.6 11.4 8.2e-11 41.8 11.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KER26868.1 - 2.4e-06 27.6 10.0 5.4e-06 26.4 10.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor Rab_bind PF16704.5 KER26868.1 - 0.029 14.4 1.1 0.029 14.4 1.1 2.1 2 0 0 2 2 2 0 Rab binding domain Golgin_A5 PF09787.9 KER26869.1 - 9.7e-33 113.9 57.8 8e-20 71.5 21.4 3.5 2 2 1 3 3 3 2 Golgin subfamily A member 5 ATG16 PF08614.11 KER26869.1 - 0.0022 18.3 8.7 0.0022 18.3 8.7 5.1 1 1 1 4 4 4 2 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 KER26869.1 - 0.004 16.7 26.8 0.004 16.7 26.8 3.3 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 KER26869.1 - 0.012 15.7 5.8 0.012 15.7 5.8 6.4 4 3 2 6 6 6 0 TolA binding protein trimerisation T3SSipB PF16535.5 KER26869.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.6 2 1 2 4 4 4 0 Type III cell invasion protein SipB FAD-oxidase_C PF02913.19 KER26869.1 - 0.94 9.0 5.9 0.25 10.9 2.4 1.8 1 1 1 2 2 2 0 FAD linked oxidases, C-terminal domain TSC22 PF01166.18 KER26869.1 - 8.2 6.8 12.7 0.15 12.4 1.2 4.1 3 2 1 4 4 4 0 TSC-22/dip/bun family V-SNARE_C PF12352.8 KER26870.1 - 0.044 14.1 3.3 0.065 13.5 0.4 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 KER26870.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) SNARE PF05739.19 KER26870.1 - 0.89 9.6 5.4 1.9 8.6 2.0 2.4 2 0 0 2 2 2 0 SNARE domain BLOC1_2 PF10046.9 KER26870.1 - 1.6 9.1 4.8 2 8.8 0.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KER26870.1 - 4.5 7.3 5.6 4.2 7.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KER26870.1 - 6.6 7.1 5.3 34 4.8 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ebp2 PF05890.12 KER26872.1 - 4.2e-63 213.4 16.9 5.5e-63 213.0 16.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PG_binding_3 PF09374.10 KER26872.1 - 0.097 12.9 0.4 0.097 12.9 0.4 1.9 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Glyco_transf_64 PF09258.10 KER26874.1 - 1.5e-26 93.2 0.0 2.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 KER26874.1 - 3.1e-21 75.9 0.0 6.8e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Exostosin family FYVE PF01363.21 KER26875.1 - 1.1e-06 28.6 14.2 1.1e-06 28.6 14.2 3.0 2 1 0 2 2 2 1 FYVE zinc finger Pkinase PF00069.25 KER26876.1 - 5.7e-44 150.5 0.0 6e-18 65.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KER26876.1 - 1.7e-24 86.6 0.0 4.7e-13 49.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KER26876.1 - 0.00051 19.5 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER26876.1 - 0.0061 16.5 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER26876.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SNAP PF14938.6 KER26878.1 - 1.1e-97 326.9 15.0 1.2e-97 326.7 15.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KER26878.1 - 3.1e-08 33.8 6.9 0.0069 16.7 0.5 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER26878.1 - 5e-05 23.0 3.7 9.2 6.6 0.4 5.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER26878.1 - 9.1e-05 22.1 5.3 11 6.0 0.2 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KER26878.1 - 9.3e-05 21.9 3.6 0.00014 21.3 3.6 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KER26878.1 - 0.00034 20.5 15.6 0.52 10.6 0.4 6.2 7 1 0 7 7 7 2 Tetratricopeptide repeat NSF PF02071.20 KER26878.1 - 0.00055 20.2 19.5 0.22 12.4 0.3 6.4 6 0 0 6 6 6 2 Aromatic-di-Alanine (AdAR) repeat FliS PF02561.14 KER26878.1 - 0.00083 19.6 3.1 0.13 12.6 0.2 3.8 2 1 2 4 4 4 1 Flagellar protein FliS TPR_19 PF14559.6 KER26878.1 - 0.0013 19.1 3.1 0.098 13.2 0.4 4.1 3 2 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER26878.1 - 0.0024 18.0 5.3 0.02 15.1 0.3 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KER26878.1 - 0.0046 16.8 0.6 4.7 7.2 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 KER26878.1 - 0.0064 15.6 7.7 0.6 9.2 6.4 2.7 1 1 0 1 1 1 1 Spatacsin C-terminus DUF4368 PF14287.6 KER26878.1 - 0.017 15.4 0.7 0.078 13.3 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4368) DUF357 PF04010.13 KER26878.1 - 0.031 14.4 1.4 1.1 9.3 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF357) TPR_16 PF13432.6 KER26878.1 - 0.05 14.3 3.2 0.17 12.5 0.0 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 KER26878.1 - 0.051 13.3 6.3 1.4 8.6 6.2 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 KER26878.1 - 0.059 13.6 6.8 29 5.2 0.0 5.3 5 1 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KER26878.1 - 0.062 14.0 0.2 1.3 9.8 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat RPN7 PF10602.9 KER26878.1 - 0.15 11.7 5.8 6.8 6.4 5.5 2.5 1 1 0 1 1 1 0 26S proteasome subunit RPN7 FRB_dom PF08771.11 KER26878.1 - 1.3 9.5 4.8 1.4 9.4 0.7 2.8 1 1 0 2 2 2 0 FKBP12-rapamycin binding domain TPR_6 PF13174.6 KER26878.1 - 2.1 9.2 8.5 13 6.6 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER26878.1 - 2.5 7.9 9.2 7.2 6.4 0.4 4.7 5 1 0 5 5 5 0 TPR repeat SNAP PF14938.6 KER26879.1 - 2.5e-13 50.1 0.1 2.9e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF4368 PF14287.6 KER26879.1 - 0.0048 17.2 0.0 0.0064 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) RACo_linker PF17650.1 KER26879.1 - 0.074 12.9 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 RACo linker region zf-C2H2_4 PF13894.6 KER26880.1 - 1.6e-07 31.5 32.4 0.092 13.6 2.0 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KER26880.1 - 3.2e-06 27.3 34.5 0.008 16.6 0.8 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type DUF629 PF04780.12 KER26880.1 - 0.035 12.6 4.0 0.88 8.0 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF629) HOIP-UBA PF16678.5 KER26880.1 - 0.14 12.1 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 HOIP UBA domain pair Zf_RING PF16744.5 KER26880.1 - 0.24 11.5 1.9 6.2 7.0 0.0 3.2 3 0 0 3 3 3 0 KIAA1045 RING finger zf-C2H2_jaz PF12171.8 KER26880.1 - 0.35 11.2 8.2 1.9 8.9 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER26880.1 - 1.1 9.3 14.5 0.23 11.5 1.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Elicitin PF00964.17 KER26882.1 - 0.048 13.7 0.9 0.16 12.1 0.9 1.9 1 0 0 1 1 1 0 Elicitin PDZ_6 PF17820.1 KER26886.1 - 7.7e-08 32.1 0.1 1.6e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain RVT_1 PF00078.27 KER26886.1 - 0.00031 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PDZ PF00595.24 KER26886.1 - 0.0006 20.1 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain VID27_N PF17748.1 KER26886.1 - 0.0059 16.5 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 2 VID27 N-terminal region PDZ_2 PF13180.6 KER26886.1 - 0.037 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Anp1 PF03452.14 KER26886.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Anp1 F-box-like PF12937.7 KER26889.1 - 4.2e-09 36.2 3.6 1.1e-08 34.8 3.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER26889.1 - 7.6e-09 35.2 2.2 7.6e-09 35.2 2.2 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KER26889.1 - 1e-05 25.8 0.3 1.3 9.6 0.0 4.6 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KER26889.1 - 0.49 10.6 6.2 8.3 6.8 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich repeat SIR2 PF02146.17 KER26890.1 - 7.1e-47 159.6 0.0 1.4e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KER26890.1 - 0.018 14.8 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_9 PF14369.6 KER26890.1 - 0.14 12.4 4.3 1.3 9.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KER26890.1 - 0.21 11.7 0.9 30 4.8 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain YabA PF06156.13 KER26890.1 - 0.36 11.5 7.8 0.82 10.3 3.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA zf-ribbon_3 PF13248.6 KER26890.1 - 0.38 10.2 1.8 0.54 9.7 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Exonuc_VII_L PF02601.15 KER26890.1 - 0.66 9.5 5.3 1.1 8.8 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Leu_zip PF15294.6 KER26890.1 - 0.88 9.0 9.0 1.4 8.4 9.0 1.3 1 0 0 1 1 1 0 Leucine zipper HALZ PF02183.18 KER26890.1 - 1.4 9.2 9.6 1.2 9.4 3.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 KER26890.1 - 1.8 7.4 10.3 4.7 6.0 10.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 KER26890.1 - 1.9 9.0 7.9 4.3 7.8 4.9 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UPF0449 PF15136.6 KER26890.1 - 2.7 8.5 4.6 6.1 7.4 1.2 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Jnk-SapK_ap_N PF09744.9 KER26890.1 - 3.4 7.9 11.9 5.6 7.2 1.8 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Peptidase_C2 PF00648.21 KER26892.1 - 1.8e-63 214.4 0.1 2.1e-57 194.4 0.0 2.7 3 0 0 3 3 3 2 Calpain family cysteine protease Calpain_III PF01067.22 KER26892.1 - 8e-48 162.3 0.0 1.6e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KER26892.1 - 4.8e-14 50.8 2.8 8.7e-05 21.8 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER26892.1 - 9.2e-12 43.9 0.5 7.3e-05 22.4 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KER26892.1 - 6.9e-10 38.6 6.9 7e-10 38.6 2.8 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 KER26892.1 - 7.3e-07 29.6 2.3 0.0022 18.4 0.6 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER26892.1 - 0.00022 20.6 6.4 0.28 10.7 0.1 3.6 3 0 0 3 3 3 3 EF hand Ribonuc_red_2_N PF08471.10 KER26894.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase V-set PF07686.17 KER26895.1 - 0.0018 18.4 1.1 0.54 10.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin V-set domain JmjC PF02373.22 KER26895.1 - 0.004 17.6 0.0 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Ig_3 PF13927.6 KER26895.1 - 0.14 12.8 2.4 24 5.6 0.1 3.6 4 0 0 4 4 4 0 Immunoglobulin domain Pkinase PF00069.25 KER26897.1 - 3.8e-41 141.2 0.0 3.8e-20 72.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER26897.1 - 1.1e-09 37.9 0.1 2.2e-07 30.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KER26897.1 - 0.19 10.6 0.1 0.29 10.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Vir_act_alpha_C PF10400.9 KER26897.1 - 0.23 12.2 5.5 0.48 11.1 0.0 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term Pox_ser-thr_kin PF05445.11 KER26897.1 - 0.24 10.3 0.0 0.63 8.9 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KER26897.1 - 0.46 9.2 3.4 0.22 10.3 0.1 1.9 1 1 1 2 2 2 0 Fungal protein kinase Integrase_H2C2 PF17921.1 KER26899.1 - 1.7e-13 50.4 0.7 1.7e-13 50.4 0.7 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain DUF5436 PF17504.2 KER26899.1 - 0.0086 16.4 0.1 0.11 12.8 0.1 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5436) zf-H2C2 PF09337.10 KER26899.1 - 0.019 15.2 1.3 0.033 14.4 0.2 2.0 2 0 0 2 2 2 0 H2C2 zinc finger rve PF00665.26 KER26899.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain APG6 PF04111.12 KER26900.1 - 5.4e-26 91.6 0.0 1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain G-patch PF01585.23 KER26900.1 - 2e-13 50.0 4.5 4.7e-13 48.8 4.5 1.6 1 0 0 1 1 1 1 G-patch domain APG6_N PF17675.1 KER26900.1 - 5.9e-08 33.3 15.7 5.9e-08 33.3 15.7 4.4 3 2 1 4 4 4 2 Apg6 coiled-coil region TMEM132D_C PF15706.5 KER26900.1 - 5.3e-05 22.9 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term G-patch_2 PF12656.7 KER26900.1 - 0.00015 21.8 0.7 0.00046 20.2 0.2 2.1 2 0 0 2 2 2 1 G-patch domain BH3 PF15285.6 KER26900.1 - 0.012 15.3 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting PMP1_2 PF08114.11 KER26900.1 - 0.13 12.0 0.5 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family LapA_dom PF06305.11 KER26900.1 - 0.4 10.5 4.0 17 5.3 0.2 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DivIC PF04977.15 KER26900.1 - 1.3 8.9 8.0 0.8 9.5 1.2 3.0 3 0 0 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 KER26900.1 - 2.2 8.6 6.2 0.33 11.2 0.8 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Histone PF00125.24 KER26903.1 - 1.3e-13 51.4 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C2H2 PF00096.26 KER26904.1 - 8.3e-05 22.8 14.5 0.009 16.4 4.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER26904.1 - 0.02 15.7 11.5 1.5 9.8 0.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Myb_DNA-binding PF00249.31 KER26904.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-AN1 PF01428.16 KER26905.1 - 3.7e-11 43.0 6.6 3.7e-11 43.0 6.6 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger RRM_1 PF00076.22 KER26906.1 - 6.3e-18 64.4 0.0 1.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER26906.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KER26906.1 - 0.068 13.2 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Limkain b1 eIF-1a PF01176.19 KER26907.1 - 6.8e-16 57.8 3.3 1.1e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 DNA_pol_phi PF04931.13 KER26907.1 - 2.1 6.3 14.8 3.1 5.8 14.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KER26907.1 - 2.6 6.2 9.2 3.6 5.8 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KER26907.1 - 4.2 7.8 17.7 8 6.9 17.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KER26907.1 - 8.4 5.4 16.9 12 4.9 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATE_C PF04377.15 KER26908.1 - 7.8e-47 159.3 1.1 7.8e-47 159.3 1.1 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KER26908.1 - 1.2e-07 32.0 3.6 3e-07 30.7 3.6 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sel1 PF08238.12 KER26909.1 - 2.3e-45 152.0 35.4 3.4e-08 33.9 0.9 11.2 11 0 0 11 11 11 10 Sel1 repeat Ldr_toxin PF13940.6 KER26909.1 - 0.4 10.8 3.4 0.25 11.4 0.3 2.3 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system ETF_QO PF05187.13 KER26911.1 - 6e-47 158.1 0.2 9.7e-47 157.4 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KER26911.1 - 1.1e-09 38.3 0.2 5.5e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KER26911.1 - 4.5e-07 29.3 0.1 1.7e-05 24.1 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KER26911.1 - 8.1e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KER26911.1 - 1.4e-05 24.8 0.1 3.8e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KER26911.1 - 2.1e-05 23.9 0.0 6e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KER26911.1 - 2.8e-05 23.7 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KER26911.1 - 0.00036 19.4 0.1 0.00053 18.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 KER26911.1 - 0.00049 20.1 0.0 0.00097 19.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KER26911.1 - 0.00054 19.3 0.0 0.0013 18.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KER26911.1 - 0.0006 19.0 0.0 0.005 15.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KER26911.1 - 0.0012 17.8 0.1 0.0055 15.6 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KER26911.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 KER26911.1 - 0.015 15.8 1.2 0.04 14.5 1.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 KER26911.1 - 0.052 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KER26911.1 - 0.064 13.8 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 KER26911.1 - 0.1 12.8 0.5 0.32 11.2 0.5 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain AlaDh_PNT_C PF01262.21 KER26911.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KER26911.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aquarius_N PF16399.5 KER26912.1 - 1.2e-217 724.8 1.5 1.4e-155 519.5 0.0 3.1 2 1 0 3 3 3 3 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 KER26912.1 - 2e-30 106.5 0.0 4.9e-29 101.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KER26912.1 - 1.2e-25 90.3 0.0 7.4e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KER26912.1 - 1.9e-10 41.3 0.4 8.3e-10 39.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KER26912.1 - 2.5e-07 30.6 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KER26912.1 - 7.1e-06 25.8 0.0 2.6e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KER26912.1 - 1.8e-05 24.8 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KER26912.1 - 0.00098 18.9 0.3 0.0025 17.6 0.3 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DnaB_C PF03796.15 KER26912.1 - 0.0019 17.6 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KER26912.1 - 0.0024 18.3 0.6 0.016 15.6 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain DEAD PF00270.29 KER26912.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 KER26912.1 - 0.0036 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KER26912.1 - 0.0071 15.6 0.3 0.05 12.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KER26912.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 KER26912.1 - 0.0089 15.8 0.1 0.69 9.6 0.1 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KER26912.1 - 0.012 15.9 0.2 0.17 12.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 KER26912.1 - 0.032 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KER26912.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RecA PF00154.21 KER26912.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Pes-10 PF07149.11 KER26912.1 - 0.12 11.4 0.1 3.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Pes-10 GPHH PF16905.5 KER26912.1 - 0.13 12.0 0.2 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated ATPase PF06745.13 KER26912.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Acetyltransf_18 PF18014.1 KER26912.1 - 0.2 11.5 0.2 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ANAPC4_WD40 PF12894.7 KER26913.1 - 7e-07 29.5 4.0 0.38 11.1 0.0 6.5 4 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER26913.1 - 6.2e-06 26.9 13.9 0.33 11.9 0.0 6.8 5 1 1 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 KER26913.1 - 0.00058 19.8 0.2 9.7 6.0 0.0 4.7 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KER26913.1 - 0.0033 15.5 0.1 0.2 9.6 0.1 2.4 2 0 0 2 2 2 2 IKI3 family Clathrin PF00637.20 KER26913.1 - 0.0044 16.9 0.8 0.37 10.7 0.2 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 KER26913.1 - 0.02 14.0 4.3 0.28 10.2 0.1 3.3 3 1 0 3 3 3 0 Coatomer WD associated region Tau95_N PF17682.1 KER26914.1 - 3.1e-17 63.0 0.1 2.3e-16 60.1 0.1 2.1 1 1 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 KER26914.1 - 0.0067 17.2 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain CactinC_cactus PF09732.9 KER26914.1 - 0.065 13.2 1.4 0.21 11.5 1.4 1.9 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein TUDOR_5 PF18359.1 KER26914.1 - 0.65 9.7 2.1 29 4.5 0.1 2.7 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 WD40 PF00400.32 KER26915.1 - 2.5e-32 110.4 28.1 8.7e-07 29.6 0.8 9.6 7 1 1 8 8 8 8 WD domain, G-beta repeat Tau95 PF09734.9 KER26915.1 - 1.2e-29 103.9 0.1 2.3e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RAB3GAP2_N PF14655.6 KER26915.1 - 0.027 13.8 0.0 0.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PBP_like_2 PF12849.7 KER26915.1 - 0.063 12.9 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 PBP superfamily domain Surp PF01805.20 KER26916.1 - 9.2e-28 96.0 0.2 5.4e-16 58.3 0.0 2.9 3 0 0 3 3 3 2 Surp module DRY_EERY PF09750.9 KER26916.1 - 1.6e-26 93.1 0.3 1.6e-26 93.1 0.3 3.3 3 0 0 3 3 3 1 Alternative splicing regulator SIR2_2 PF13289.6 KER26916.1 - 0.045 13.9 0.1 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 SIR2-like domain Serpin PF00079.20 KER26917.1 - 2.6e-32 112.5 0.0 2.9e-28 99.2 0.1 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) Serpin PF00079.20 KER26918.1 - 1.4e-65 222.1 0.4 1.8e-65 221.7 0.4 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Hjc PF01870.18 KER26918.1 - 0.0056 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Serpin PF00079.20 KER26919.1 - 1.7e-58 198.8 0.3 2e-58 198.5 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Dynein_light PF01221.18 KER26920.1 - 5.4e-19 68.3 4.9 1.5e-18 66.9 1.2 2.1 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER26920.1 - 3.9e-05 24.0 3.2 5.5e-05 23.5 0.7 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KER26920.1 - 0.0016 18.2 0.8 2.2 8.4 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain HTH_Mga PF08280.11 KER26920.1 - 0.0027 17.7 0.1 0.11 12.6 0.0 2.6 3 0 0 3 3 3 1 M protein trans-acting positive regulator (MGA) HTH domain EF-hand_1 PF00036.32 KER26920.1 - 0.013 15.0 0.2 0.5 10.0 0.0 3.0 2 1 0 2 2 2 0 EF hand AbiJ_NTD4 PF18863.1 KER26920.1 - 0.018 15.5 0.4 0.018 15.5 0.4 1.8 2 1 0 2 2 2 0 AbiJ N-terminal domain 4 DUF3038 PF11237.8 KER26920.1 - 0.029 14.4 0.9 0.051 13.6 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) GPHH PF16905.5 KER26920.1 - 0.044 13.5 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Imm6 PF14434.6 KER26920.1 - 0.054 13.4 1.2 0.07 13.1 0.3 1.8 2 0 0 2 2 2 0 Immunity protein Imm6 EF-hand_9 PF14658.6 KER26920.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF4841 PF16129.5 KER26920.1 - 0.094 13.0 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) EF-hand_4 PF12763.7 KER26920.1 - 0.097 12.6 0.4 0.21 11.6 0.2 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dynein_light PF01221.18 KER26921.1 - 3.5e-16 59.3 0.4 3.5e-16 59.3 0.4 1.9 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER26921.1 - 0.0058 17.1 1.5 0.0078 16.7 0.7 1.6 2 0 0 2 2 2 1 EF-hand domain pair Dynein_light PF01221.18 KER26922.1 - 9.2e-16 57.9 0.1 3.2e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 Dynein light chain type 1 EF-hand_6 PF13405.6 KER26922.1 - 0.0021 17.9 0.1 11 6.3 0.0 3.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 KER26922.1 - 0.0022 18.3 0.0 0.0099 16.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KER26922.1 - 0.0071 15.8 0.1 4.7 7.0 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KER26922.1 - 0.009 16.4 1.3 0.039 14.4 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair Rad4 PF03835.15 KER26922.1 - 0.073 12.8 1.4 2.2 8.0 0.0 2.3 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain AA_kinase PF00696.28 KER26923.1 - 1.7e-32 113.0 0.1 6.7e-32 111.0 0.1 1.9 2 0 0 2 2 2 1 Amino acid kinase family Aldedh PF00171.22 KER26923.1 - 3.8e-05 22.4 0.4 7.6e-05 21.4 0.4 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2 PF00152.20 KER26927.1 - 1.8e-75 253.9 0.2 2.3e-75 253.6 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KER26927.1 - 3.3e-06 27.0 0.0 6.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KER26927.1 - 2e-05 24.2 0.5 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Med28 PF11594.8 KER26928.1 - 0.019 15.1 0.2 0.022 14.8 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 KxDL PF10241.9 KER26928.1 - 0.056 13.7 1.1 1.4 9.3 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Cystatin PF00031.21 KER26930.1 - 1.1e-25 89.7 25.6 9.3e-05 22.6 0.1 13.6 13 1 1 14 14 14 8 Cystatin domain Cathelicidins PF00666.17 KER26930.1 - 8.5e-09 35.6 21.4 0.82 10.0 0.1 11.6 12 2 1 13 13 13 3 Cathelicidin SQAPI PF16845.5 KER26930.1 - 0.00015 22.0 0.8 2.4 8.6 0.0 5.1 5 0 0 5 5 5 2 Aspartic acid proteinase inhibitor DUF2300 PF10062.9 KER26930.1 - 0.41 10.7 3.8 13 5.9 0.1 3.5 3 0 0 3 3 3 0 Predicted secreted protein (DUF2300) Baculo_LEF-3 PF05847.11 KER26932.1 - 0.029 13.6 0.5 0.034 13.3 0.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) DUF3271 PF11675.8 KER26933.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Cystatin PF00031.21 KER26934.1 - 1.1e-05 25.6 8.0 0.064 13.5 0.0 5.0 5 0 0 5 5 5 3 Cystatin domain adh_short_C2 PF13561.6 KER26936.1 - 5.9e-61 206.0 0.0 7.5e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER26936.1 - 7.8e-51 172.3 0.0 1.1e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER26936.1 - 1.7e-10 41.1 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Cpn60_TCP1 PF00118.24 KER26937.1 - 8.2e-165 549.1 9.6 9.5e-165 548.9 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PWWP PF00855.17 KER26939.1 - 4.1e-10 39.9 0.8 1.9e-09 37.8 0.4 2.3 2 0 0 2 2 2 1 PWWP domain ADK_lid PF05191.14 KER26939.1 - 0.024 14.6 0.1 0.26 11.3 0.1 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Collagen PF01391.18 KER26941.1 - 2.8e-151 491.4 608.1 4.6e-09 35.9 29.1 19.8 3 3 12 15 15 15 12 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER26941.1 - 7.1e-44 149.8 0.0 9.5e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain ERK-JNK_inhib PF15002.6 KER26944.1 - 4.8e-23 81.9 0.0 5.8e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Rotavirus_VP1 PF12289.8 KER26944.1 - 0.013 14.6 0.0 0.33 10.0 0.0 2.0 1 1 1 2 2 2 0 Rotavirus VP1 C-terminal domain Pro_dh PF01619.18 KER26950.1 - 1.1e-80 271.3 0.0 3.6e-79 266.4 0.0 2.3 1 1 0 1 1 1 1 Proline dehydrogenase Dockerin_1 PF00404.18 KER26950.1 - 0.074 13.3 0.5 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain Mod_r PF07200.13 KER26952.1 - 0.0013 18.9 4.1 0.0013 18.9 4.1 3.6 2 1 2 4 4 3 1 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.12 KER26952.1 - 0.0021 18.1 6.1 0.0021 18.1 6.1 3.0 2 1 0 2 2 1 1 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 KER26952.1 - 0.02 14.9 35.7 0.068 13.2 4.3 4.2 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KER26952.1 - 0.091 13.2 35.2 0.092 13.2 8.8 2.4 1 1 0 2 2 2 0 Fez1 Lebercilin PF15619.6 KER26952.1 - 0.13 11.9 41.6 0.073 12.7 10.2 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IFP_35_N PF07334.13 KER26952.1 - 0.21 11.7 0.2 0.21 11.7 0.2 3.1 4 0 0 4 4 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GAS PF13851.6 KER26952.1 - 0.29 10.5 38.2 0.76 9.1 5.8 3.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KER26952.1 - 0.45 9.5 31.9 1.2 8.1 7.2 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KER26952.1 - 0.49 10.2 38.0 0.12 12.2 1.3 4.2 2 2 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KER26952.1 - 0.62 8.9 34.7 0.53 9.1 3.5 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.14 KER26952.1 - 1.4 9.2 31.8 0.22 11.9 3.0 3.1 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 KER26952.1 - 1.5 8.6 27.7 0.65 9.8 4.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF948 PF06103.11 KER26952.1 - 1.6 9.1 15.4 20 5.5 0.1 5.0 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Rab5-bind PF09311.11 KER26952.1 - 1.6 8.1 35.1 0.14 11.5 8.3 3.6 2 2 1 3 3 3 0 Rabaptin-like protein DUF1319 PF07028.11 KER26952.1 - 1.6 9.0 11.6 0.095 12.9 2.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) YabA PF06156.13 KER26952.1 - 1.9 9.2 30.9 0.25 12.0 1.7 4.8 1 1 4 5 5 5 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 KER26952.1 - 2.7 8.3 29.5 4.3 7.6 5.1 4.4 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.9 KER26952.1 - 3.3 7.7 37.5 0.14 12.2 7.7 3.7 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KER26952.1 - 4.7 7.7 41.2 0.22 12.1 8.1 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region LRR_8 PF13855.6 KER26953.1 - 4.3e-14 52.0 0.1 1.5e-07 31.1 0.1 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KER26953.1 - 1.8e-10 40.6 0.0 3.5e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KER26953.1 - 4.5e-10 39.6 0.6 1.3e-06 28.7 0.0 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER26953.1 - 0.062 13.9 0.3 77 4.5 0.0 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat Acyltransferase PF01553.21 KER26954.1 - 5.6e-20 71.3 0.0 8.1e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Exostosin PF03016.15 KER26956.1 - 5.5e-52 176.8 0.1 3.9e-51 174.1 0.0 2.2 2 1 0 2 2 2 1 Exostosin family Glyco_transf_64 PF09258.10 KER26956.1 - 5.9e-40 137.1 0.1 1.3e-39 136.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DAGK_acc PF00609.19 KER26957.1 - 8.5e-81 270.0 0.0 1.4e-51 175.0 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KER26957.1 - 1.2e-22 79.9 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 KER26957.1 - 4.9e-13 49.5 0.2 2.2e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 KER26957.1 - 1.6e-09 37.5 32.0 1.6e-06 27.9 8.0 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_C34 PF05413.11 KER26957.1 - 0.011 15.9 0.0 9.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase PDGLE PF13190.6 KER26957.1 - 0.11 12.4 0.1 25 4.8 0.0 2.4 2 0 0 2 2 2 0 PDGLE domain Orthopox_F8 PF05886.11 KER26959.1 - 0.092 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus F8 protein rve PF00665.26 KER26961.1 - 6.2e-21 74.8 0.0 1.9e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PID PF00640.23 KER26961.1 - 1.4e-20 73.7 0.0 2.4e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 KER26961.1 - 6.1e-16 58.3 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RVT_1 PF00078.27 KER26961.1 - 9.4e-10 38.4 0.2 5.2e-09 35.9 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KER26961.1 - 0.0021 18.1 7.1 0.0038 17.3 1.4 3.0 2 1 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KER26961.1 - 0.0022 18.5 0.0 0.0053 17.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 KER26961.1 - 0.0044 16.8 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.20 KER26961.1 - 0.021 15.1 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KER26961.1 - 0.024 15.3 0.0 0.056 14.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 KER26965.1 - 8.5e-46 156.5 0.0 1.8e-45 155.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER26965.1 - 4.8e-20 71.9 0.0 1.4e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KER26965.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Blt1 PF12754.7 KER26965.1 - 0.24 11.7 1.2 0.72 10.2 1.2 1.8 1 0 0 1 1 1 0 Blt1 N-terminal domain DHHC PF01529.20 KER26972.1 - 2.2e-24 86.1 20.3 1.7e-22 79.9 7.0 2.9 3 0 0 3 3 3 2 DHHC palmitoyltransferase MDD_C PF18376.1 KER26972.1 - 0.031 14.0 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain SASA PF03629.18 KER26972.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase TRAPPC9-Trs120 PF08626.11 KER26973.1 - 9.3e-06 23.3 0.0 1.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KER26973.1 - 0.012 15.9 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER26973.1 - 0.8 10.0 2.0 0.95 9.7 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_15 PF09445.10 KER26977.1 - 5.3e-33 113.9 0.0 9.9e-33 113.0 0.0 1.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KER26977.1 - 0.00052 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KER26977.1 - 0.0022 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KER26977.1 - 0.0022 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KER26977.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein SAM_MT PF04445.13 KER26977.1 - 0.047 13.1 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase UPF0020 PF01170.18 KER26977.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 KER26977.1 - 0.051 12.6 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KER26977.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 KER26977.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 KER26977.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KER26977.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DC_STAMP PF07782.13 KER26978.1 - 3.5e-38 131.4 0.0 9.9e-38 129.9 0.0 1.8 1 0 0 1 1 1 1 DC-STAMP-like protein DUF555 PF04475.12 KER26978.1 - 0.084 13.2 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF555) zf-Sec23_Sec24 PF04810.15 KER26978.1 - 1.7 8.7 8.4 7.5 6.7 6.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.7 KER26978.1 - 6 7.0 7.8 28 4.9 1.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon Carn_acyltransf PF00755.20 KER26979.1 - 8.2e-161 536.6 0.0 3.1e-105 353.0 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase RVT_1 PF00078.27 KER26980.1 - 0.045 13.2 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TRAM_LAG1_CLN8 PF03798.16 KER26981.1 - 7.1e-21 74.9 8.3 7.1e-21 74.9 8.3 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KER26981.1 - 4.7e-14 51.8 1.5 6e-14 51.5 0.1 1.9 2 0 0 2 2 2 1 TRAM1-like protein STT3 PF02516.14 KER26982.1 - 2e-85 287.6 29.1 2.1e-84 284.2 29.1 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 KER26983.1 - 3e-18 66.0 0.7 3.2e-18 65.9 0.7 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit RRM_1 PF00076.22 KER26985.1 - 1.2e-17 63.5 0.0 2.4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER26985.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF1970 PF09301.10 KER26985.1 - 0.057 13.7 0.2 0.057 13.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) Iso_dh PF00180.20 KER26986.1 - 2.1e-67 227.8 0.0 3.2e-49 168.0 0.0 2.6 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF1330 PF07045.11 KER26986.1 - 0.078 13.3 0.0 1.7 9.0 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1330) KCNQ_channel PF03520.14 KER26987.1 - 0.079 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 KER26988.1 - 7.4e-13 48.3 4.4 9.1e-13 48.0 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER26988.1 - 5.3e-12 45.5 2.5 5.3e-12 45.5 2.5 1.9 2 0 0 2 2 2 1 Ion channel SecE PF00584.20 KER26988.1 - 0.034 14.1 0.2 0.034 14.1 0.2 2.6 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Lig_chan PF00060.26 KER26988.1 - 1.8 8.4 5.3 0.22 11.3 0.6 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel IPPT PF01715.17 KER26991.1 - 2.8e-17 63.3 0.0 4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KER26991.1 - 0.00042 19.8 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 KER26991.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IstB_IS21 PF01695.17 KER26991.1 - 0.064 13.0 0.2 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KER26991.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 KER26991.1 - 0.11 12.2 0.2 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KER26991.1 - 0.13 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CAMSAP_CKK PF08683.11 KER26992.1 - 5.2e-12 46.0 0.1 9.8e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Asp PF00026.23 KER26993.1 - 3e-35 122.1 0.0 1.4e-21 77.3 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER26993.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Peptidase_C13 PF01650.18 KER26994.1 - 3.3e-66 223.4 2.9 5.5e-37 127.7 0.1 2.2 1 1 1 2 2 2 2 Peptidase C13 family EF-hand_2 PF09068.11 KER26994.1 - 0.083 13.0 0.0 9.5 6.4 0.7 2.6 2 1 0 2 2 2 0 EF hand DUF4899 PF16240.5 KER26994.1 - 0.12 11.6 0.7 0.26 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) Antiterm PF03589.13 KER26996.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Antitermination protein SAM_2 PF07647.17 KER26997.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Bcr-Abl_Oligo PF09036.10 KER26997.1 - 0.042 13.8 0.3 8.1 6.5 0.1 2.5 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF2721 PF11026.8 KER27000.1 - 0.0017 18.3 8.4 0.0017 18.3 8.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2721) 7TM_GPCR_Srh PF10318.9 KER27000.1 - 0.25 10.3 8.7 1.3 8.0 8.7 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Amastin PF07344.11 KER27000.1 - 0.37 10.6 10.8 0.29 11.0 9.7 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein MARVEL PF01284.23 KER27000.1 - 0.69 9.9 15.9 1.1 9.3 6.7 2.1 1 1 1 2 2 2 0 Membrane-associating domain Saf_2TM PF18303.1 KER27000.1 - 2.9 7.5 7.8 0.42 10.2 3.7 1.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain SUR7 PF06687.12 KER27000.1 - 4.5 6.9 19.2 0.36 10.4 13.3 1.7 1 1 1 2 2 2 0 SUR7/PalI family SGS PF05002.15 KER27002.1 - 1.1e-32 112.0 0.6 1.8e-32 111.3 0.6 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KER27002.1 - 0.00094 20.2 0.0 0.0023 18.9 0.0 1.7 2 0 0 2 2 2 1 CS domain DUF1828 PF08861.10 KER27002.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF1828 RabGAP-TBC PF00566.18 KER27003.1 - 1.5e-14 54.2 2.6 4e-14 52.8 1.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain zinc_ribbon_10 PF10058.9 KER27005.1 - 1.9e-19 69.1 0.9 2.9e-19 68.5 0.9 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein WD40 PF00400.32 KER27006.1 - 6.4e-35 118.6 19.4 8.3e-08 32.8 2.6 7.5 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER27006.1 - 1.5e-15 57.2 1.6 0.00012 22.4 0.2 4.8 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ARL2_Bind_BART PF11527.8 KER27006.1 - 0.15 12.2 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART CENP-T_C PF15511.6 KER27007.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KER27007.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KER27007.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KER27007.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER27007.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KER27007.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KER27007.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KER27007.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) adh_short PF00106.25 KER27008.1 - 3.9e-15 55.8 0.1 3e-13 49.7 0.1 2.6 1 1 0 1 1 1 1 short chain dehydrogenase RRM_1 PF00076.22 KER27009.1 - 0.047 13.5 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KER27009.1 - 0.06 14.1 0.2 0.19 12.4 0.2 1.8 1 0 0 1 1 1 0 Torus domain Citrate_synt PF00285.21 KER27011.1 - 2.6e-21 76.1 0.0 2.9e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 KER27012.1 - 1.5e-77 261.1 0.0 1.9e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 KER27012.1 - 0.048 13.9 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 PAS fold PIN_4 PF13638.6 KER27016.1 - 0.0054 17.0 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain Microvir_J PF04726.13 KER27017.1 - 1.9 8.6 6.5 0.16 12.0 1.3 1.9 3 0 0 3 3 3 0 Microvirus J protein Cadherin PF00028.17 KER27020.1 - 8.7e-68 224.8 5.8 9e-16 58.1 0.0 9.8 7 2 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER27020.1 - 5.5e-09 35.8 0.5 0.005 16.6 0.0 4.7 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 KER27020.1 - 0.0021 18.0 7.5 11 6.1 0.0 6.3 6 1 0 6 6 6 2 Cadherin-like Tubulin PF00091.25 KER27021.1 - 5.4e-18 65.9 0.0 5.7e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Orai-1 PF07856.12 KER27024.1 - 4.4e-35 120.9 9.8 5.6e-35 120.6 9.8 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity CoA_binding_3 PF13727.6 KER27024.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 CoA-binding domain FtsX PF02687.21 KER27024.1 - 6.3 7.3 16.6 52 4.4 15.8 2.2 1 1 0 1 1 1 0 FtsX-like permease family Cadherin PF00028.17 KER27026.1 - 0.0017 18.7 0.0 0.0087 16.5 0.0 2.1 1 1 0 1 1 1 1 Cadherin domain DUF3533 PF12051.8 KER27026.1 - 0.12 11.3 0.3 0.18 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Cadherin PF00028.17 KER27027.1 - 9.1e-48 160.7 0.7 4.5e-12 46.2 0.1 7.4 6 1 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KER27027.1 - 1.8e-09 37.3 1.6 5e-05 23.1 0.1 4.3 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 KER27027.1 - 0.13 12.6 0.0 0.66 10.3 0.0 2.2 2 0 0 2 2 2 0 RET Cadherin like domain 1 DUF1801 PF08818.11 KER27028.1 - 0.043 14.3 0.1 0.058 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DU1801) Arf PF00025.21 KER27031.1 - 3.2e-50 170.0 0.0 3.9e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KER27031.1 - 1e-09 38.2 0.0 1.3e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KER27031.1 - 2e-08 33.9 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KER27031.1 - 2.7e-08 33.4 0.1 5.4e-08 32.4 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 KER27031.1 - 4.7e-08 33.3 0.0 6.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KER27031.1 - 4.5e-07 29.5 0.0 6.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KER27031.1 - 0.00021 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KER27031.1 - 0.035 13.1 0.0 0.058 12.4 0.0 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KER27031.1 - 0.074 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2040 PF09745.9 KER27032.1 - 2.9e-30 104.8 15.4 2.9e-30 104.8 15.4 2.4 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.25 KER27033.1 - 9.9e-32 110.3 0.0 2.4e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27033.1 - 1.4e-23 83.5 0.0 2.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER27033.1 - 0.0001 22.3 3.9 0.00029 20.8 3.7 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER27033.1 - 0.00014 21.3 0.3 0.00043 19.7 0.3 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER27033.1 - 0.00045 19.1 0.1 0.00078 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER27033.1 - 0.087 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HisKA_3 PF07730.13 KER27033.1 - 2.3 8.8 9.4 3.7 8.1 0.3 3.9 4 0 0 4 4 4 0 Histidine kinase UCR_6-4kD PF08997.10 KER27034.1 - 1.9e-08 34.1 0.5 2.3e-08 33.9 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_C2 PF00648.21 KER27035.1 - 1e-53 182.3 0.2 1.7e-32 112.7 0.0 3.5 2 1 2 4 4 4 2 Calpain family cysteine protease MIT PF04212.18 KER27035.1 - 8e-20 70.7 8.8 7.2e-13 48.4 0.6 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Calpain_III PF01067.22 KER27035.1 - 6e-17 62.2 0.1 5.8e-10 39.6 0.0 2.9 2 0 0 2 2 2 2 Calpain large subunit, domain III DrsE PF02635.15 KER27035.1 - 0.0098 16.2 0.3 1.4 9.3 0.1 2.6 2 0 0 2 2 2 1 DsrE/DsrF-like family TPR_2 PF07719.17 KER27035.1 - 0.061 13.5 3.4 11 6.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER27035.1 - 0.19 12.0 1.5 16 6.0 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER27035.1 - 0.31 11.0 2.7 12 5.9 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 KER27037.1 - 6.9e-06 26.0 0.0 0.038 13.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 PRORP PF16953.5 KER27038.1 - 1.1e-23 84.0 1.5 2.2e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 KER27038.1 - 0.024 14.0 0.3 0.063 12.6 0.3 1.6 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP SopA PF13981.6 KER27038.1 - 0.13 12.7 0.0 0.61 10.5 0.0 2.1 2 0 0 2 2 2 0 SopA-like central domain DUF678 PF05077.12 KER27038.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) RCS1 PF07326.11 KER27039.1 - 0.074 13.0 1.1 0.16 11.8 1.1 1.5 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 DUF2277 PF10041.9 KER27039.1 - 0.13 12.6 0.0 59 4.1 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) LSM PF01423.22 KER27040.1 - 1.2e-13 50.5 0.2 3.9e-13 48.9 0.4 1.8 2 0 0 2 2 2 1 LSM domain DUF4743 PF15916.5 KER27042.1 - 6.7e-33 113.2 0.0 1.1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RVT_1 PF00078.27 KER27042.1 - 2.4e-11 43.6 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NUDIX PF00293.28 KER27042.1 - 1.9e-07 31.2 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Clat_adaptor_s PF01217.20 KER27044.1 - 7e-47 158.9 4.6 9.3e-45 152.1 4.6 2.1 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Kinesin PF00225.23 KER27045.1 - 9.7e-76 254.8 2.8 6.8e-53 179.7 0.0 3.3 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KER27045.1 - 1.4e-38 132.2 0.1 9.9e-37 126.2 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding DnaJ PF00226.31 KER27045.1 - 4.5e-08 33.1 1.2 1.6e-07 31.4 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain RVT_1 PF00078.27 KER27045.1 - 2.7e-06 27.1 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_GP20 PF06810.11 KER27045.1 - 3.1 7.6 15.1 0.07 12.9 5.4 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 SpecificRecomb PF10136.9 KER27045.1 - 4 5.6 8.4 8.4 4.6 8.4 1.4 1 0 0 1 1 1 0 Site-specific recombinase Metallophos PF00149.28 KER27046.1 - 1.4e-23 84.5 0.0 2.3e-16 60.9 0.0 3.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 KER27046.1 - 2.9e-11 42.1 0.2 0.00011 21.5 0.3 4.1 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KER27046.1 - 8.1e-09 35.8 0.8 7.2e-05 23.2 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KER27046.1 - 1.7e-07 30.6 0.1 0.0086 15.9 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 KER27046.1 - 1.6e-05 24.1 0.9 0.0057 16.1 0.5 3.5 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 KER27046.1 - 2.4e-05 24.1 0.2 0.00024 20.9 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 KER27046.1 - 0.07 13.1 0.1 1.1 9.3 0.0 2.8 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand UBD PF16455.5 KER27048.1 - 1.1e-18 67.4 0.0 1.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain RhoGAP PF00620.27 KER27049.1 - 6.5e-22 78.0 0.6 2.8e-18 66.2 0.6 2.4 2 0 0 2 2 2 2 RhoGAP domain MyTH4 PF00784.17 KER27049.1 - 3e-18 66.3 0.0 2.7e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 KER27049.1 - 3.2e-07 30.3 4.0 0.0072 16.4 0.0 2.7 2 0 0 2 2 2 2 WW domain RVT_1 PF00078.27 KER27050.1 - 2.3e-10 40.4 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1961 PF09224.11 KER27051.1 - 0.05 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Arfaptin PF06456.13 KER27052.1 - 0.044 13.3 0.2 0.051 13.1 0.2 1.1 1 0 0 1 1 1 0 Arfaptin-like domain Tmpp129 PF10272.9 KER27052.1 - 0.069 12.4 0.3 0.075 12.3 0.3 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor LIM PF00412.22 KER27053.1 - 5.3e-05 23.4 5.1 5.3e-05 23.4 5.1 1.6 2 0 0 2 2 2 1 LIM domain Fer4_9 PF13187.6 KER27053.1 - 0.34 11.1 11.9 0.59 10.3 7.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain TNFR_c6 PF00020.18 KER27053.1 - 0.8 10.2 15.0 0.51 10.8 1.2 2.9 1 1 2 3 3 3 0 TNFR/NGFR cysteine-rich region zf_UBZ PF18439.1 KER27053.1 - 0.8 9.3 4.8 0.52 10.0 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger NS3_envE PF02723.14 KER27053.1 - 0.94 9.6 3.3 2.2 8.4 0.4 2.1 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Rep_fac-A_C PF08646.10 KER27053.1 - 3.6 7.3 11.4 0.3 10.8 4.7 2.0 1 1 0 2 2 2 0 Replication factor-A C terminal domain LIM PF00412.22 KER27054.1 - 4.6e-23 81.2 25.3 2.2e-12 47.0 5.8 3.2 3 0 0 3 3 3 2 LIM domain DiS_P_DiS PF06750.13 KER27054.1 - 0.27 11.4 7.9 4.3 7.5 1.8 2.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 KER27054.1 - 0.31 11.1 15.4 0.65 10.1 1.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon DUF2072 PF09845.9 KER27054.1 - 2.8 8.2 7.7 7.1 6.9 0.7 2.5 2 1 0 2 2 2 0 Zn-ribbon containing protein LIM PF00412.22 KER27055.1 - 4.3e-11 42.9 28.3 2.7e-06 27.5 7.7 3.7 4 0 0 4 4 4 3 LIM domain LIM PF00412.22 KER27056.1 - 2.9e-23 81.9 40.1 9.8e-10 38.5 8.7 3.3 3 0 0 3 3 3 3 LIM domain Sgf11 PF08209.11 KER27056.1 - 0.19 11.3 0.2 0.19 11.3 0.2 4.3 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) LIM PF00412.22 KER27058.1 - 5.1e-65 215.6 87.5 1.8e-12 47.3 1.6 7.4 7 0 0 7 7 7 7 LIM domain DUF4476 PF14771.6 KER27058.1 - 0.57 10.5 3.3 4.9 7.5 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4476) RecO_C PF02565.15 KER27058.1 - 0.58 9.9 4.7 0.51 10.1 0.5 3.1 2 0 0 2 2 2 0 Recombination protein O C terminal Rad50_zn_hook PF04423.14 KER27058.1 - 8.5 6.3 9.5 6.9 6.6 0.1 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif LIM PF00412.22 KER27059.1 - 5.3e-07 29.8 5.2 1e-06 28.9 5.2 1.4 1 0 0 1 1 1 1 LIM domain Xlink PF00193.17 KER27059.1 - 0.069 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Extracellular link domain PsaL PF02605.15 KER27062.1 - 0.0055 16.4 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI TMEM154 PF15102.6 KER27062.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 KER27062.1 - 0.031 14.2 0.2 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3328 PF11807.8 KER27062.1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Syndecan PF01034.20 KER27062.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.11 KER27062.1 - 0.061 13.3 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF5305 PF17231.2 KER27062.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 KER27062.1 - 0.1 13.5 0.0 0.13 13.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 KER27062.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Jnk-SapK_ap_N PF09744.9 KER27064.1 - 1.5e-36 125.9 9.7 1.5e-36 125.9 9.7 2.5 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 KER27064.1 - 8.2e-16 58.0 0.7 5.7e-15 55.3 0.0 2.8 2 0 0 2 2 2 1 Rab interacting lysosomal protein GAS PF13851.6 KER27064.1 - 0.0069 15.8 20.0 0.59 9.4 19.0 3.1 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 KER27064.1 - 0.055 13.5 0.4 0.055 13.5 0.4 3.3 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain GDH_N PF12466.8 KER27064.1 - 0.07 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal XPC-binding PF09280.11 KER27064.1 - 0.082 12.7 0.2 0.082 12.7 0.2 2.9 3 0 0 3 3 3 0 XPC-binding domain ATG16 PF08614.11 KER27064.1 - 0.27 11.4 31.0 5.1 7.3 0.1 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF2935 PF11155.8 KER27064.1 - 0.29 11.5 3.2 2 8.8 0.3 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF2935) SAP PF02037.27 KER27064.1 - 1.1 9.1 7.2 3.1 7.7 0.1 4.2 4 0 0 4 4 4 0 SAP domain Leu_zip PF15294.6 KER27064.1 - 1.3 8.5 23.5 0.39 10.2 11.9 2.7 2 1 1 3 3 3 0 Leucine zipper DUF4407 PF14362.6 KER27064.1 - 1.8 7.9 15.2 2.8 7.2 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc29 PF17082.5 KER27064.1 - 3.1 7.6 17.4 2.2 8.1 9.2 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 Presenilin PF01080.17 KER27066.1 - 6.5e-151 502.6 8.4 7.5e-151 502.4 8.4 1.0 1 0 0 1 1 1 1 Presenilin Troponin PF00992.20 KER27068.1 - 9.6e-18 64.8 16.0 9.6e-18 64.8 16.0 2.3 2 0 0 2 2 2 1 Troponin Mis14 PF08641.12 KER27068.1 - 0.01 16.1 0.4 0.01 16.1 0.4 3.5 4 0 0 4 4 4 0 Kinetochore protein Mis14 like Histone PF00125.24 KER27069.1 - 1.1e-19 71.1 1.1 1.2e-19 70.9 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KER27069.1 - 0.0013 19.2 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KER27069.1 - 0.0027 17.9 0.4 0.0049 17.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CNDH2_C PF16858.5 KER27069.1 - 0.049 13.5 0.2 0.054 13.4 0.2 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3915 PF13054.6 KER27069.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ribosomal_L24e PF01246.20 KER27070.1 - 7.9e-30 102.9 7.3 7.9e-30 102.9 7.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e BRO1 PF03097.18 KER27072.1 - 2.9e-05 23.1 0.0 4.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain CLIP1_ZNF PF16641.5 KER27075.1 - 1.6e-17 62.9 17.4 9.3e-09 34.9 4.0 2.3 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 KER27075.1 - 4.4e-05 22.5 20.0 4.4e-05 22.5 20.0 2.7 2 1 1 3 3 3 1 Spc7 kinetochore protein FliJ PF02050.16 KER27075.1 - 0.00016 21.9 17.9 0.04 14.2 0.3 2.7 2 1 0 2 2 2 2 Flagellar FliJ protein DUF948 PF06103.11 KER27075.1 - 0.012 15.9 7.0 0.045 14.0 1.8 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CALCOCO1 PF07888.11 KER27075.1 - 0.02 13.8 23.8 0.022 13.7 22.8 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 KER27075.1 - 0.037 14.4 22.0 0.5 10.8 8.5 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) AAA_13 PF13166.6 KER27075.1 - 0.039 12.6 13.2 0.22 10.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KER27075.1 - 0.043 13.8 14.8 1.2 9.2 1.1 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) MerR-DNA-bind PF09278.11 KER27075.1 - 0.16 12.5 0.4 0.16 12.5 0.4 5.0 4 2 2 6 6 5 0 MerR, DNA binding HMMR_N PF15905.5 KER27075.1 - 0.19 11.1 26.3 7.5 5.9 26.3 2.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KER27075.1 - 0.23 10.8 18.6 1.3 8.3 18.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RBD-FIP PF09457.10 KER27075.1 - 0.24 11.4 2.3 19 5.3 0.0 3.4 2 0 0 2 2 2 0 FIP domain APG17 PF04108.12 KER27075.1 - 0.25 10.4 17.8 0.24 10.4 5.6 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 OEP PF02321.18 KER27075.1 - 0.28 10.9 11.2 0.44 10.3 10.5 1.6 1 1 0 1 1 1 0 Outer membrane efflux protein DUF3450 PF11932.8 KER27075.1 - 0.39 10.0 28.8 0.031 13.6 1.9 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) GTP-bdg_M PF16360.5 KER27075.1 - 0.44 11.2 13.0 0.87 10.2 0.7 3.8 2 2 1 3 3 3 0 GTP-binding GTPase Middle Region Phage_GP20 PF06810.11 KER27075.1 - 0.49 10.2 18.4 6.3 6.6 0.0 4.0 1 1 2 4 4 4 0 Phage minor structural protein GP20 Fez1 PF06818.15 KER27075.1 - 0.73 10.3 21.8 2.4 8.6 12.0 2.8 1 1 2 3 3 3 0 Fez1 DUF4337 PF14235.6 KER27075.1 - 0.91 9.6 0.0 0.91 9.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) SlyX PF04102.12 KER27075.1 - 1.3 9.7 24.7 20 5.9 3.6 5.4 2 1 3 5 5 5 0 SlyX PilJ PF13675.6 KER27075.1 - 1.4 9.0 12.0 5.3 7.1 4.8 3.3 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF724 PF05266.14 KER27075.1 - 1.4 8.7 15.6 0.28 11.0 6.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) COG2 PF06148.11 KER27075.1 - 1.6 8.9 18.5 0.054 13.6 8.0 3.3 2 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 KER27075.1 - 1.6 9.3 37.9 1.2 9.7 24.4 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Rab_bind PF16704.5 KER27075.1 - 2.1 8.4 10.8 0.74 9.9 1.1 3.4 3 1 1 4 4 2 0 Rab binding domain SHE3 PF17078.5 KER27075.1 - 2.2 8.0 15.9 16 5.1 15.8 2.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 KER27075.1 - 2.2 8.5 17.0 0.44 10.7 2.6 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 KER27075.1 - 2.4 8.5 17.9 0.056 13.8 7.0 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Sec20 PF03908.13 KER27075.1 - 3.6 7.6 13.0 5.2 7.1 3.2 3.1 3 1 0 3 3 3 0 Sec20 Atg14 PF10186.9 KER27075.1 - 4.5 6.3 18.2 10 5.1 17.9 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GBP_C PF02841.14 KER27075.1 - 4.6 6.6 16.3 6.5 6.1 15.5 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TMF_DNA_bd PF12329.8 KER27075.1 - 4.9 7.2 31.4 0.17 11.9 1.2 5.2 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 KER27075.1 - 5.6 5.4 10.9 5 5.6 6.1 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Lectin_N PF03954.14 KER27075.1 - 6.1 6.6 17.9 1.2 8.9 1.9 3.6 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KER27075.1 - 6.5 7.3 11.8 6.7 7.3 5.9 3.6 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 KER27075.1 - 7.5 7.1 21.9 20 5.7 9.8 3.6 1 1 2 3 3 3 0 Spectrin repeat Ribosomal_60s PF00428.19 KER27078.1 - 1.9e-19 70.0 3.3 2.4e-19 69.7 3.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ToxB_N PF18224.1 KER27079.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 ToxB N-terminal domain DSL PF01414.19 KER27080.1 - 3.8e-11 43.1 3.9 3.8e-11 43.1 3.9 3.9 4 0 0 4 4 4 1 Delta serrate ligand EGF PF00008.27 KER27080.1 - 4.2e-11 42.9 43.3 5.2e-06 26.6 4.9 5.0 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 KER27080.1 - 0.00012 22.6 4.4 0.00012 22.6 4.4 5.3 4 0 0 4 4 4 1 Human growth factor-like EGF EGF_2 PF07974.13 KER27080.1 - 0.0022 18.3 5.9 0.0022 18.3 5.9 5.1 5 0 0 5 5 5 2 EGF-like domain TAFA PF12020.8 KER27080.1 - 0.015 15.7 1.9 0.015 15.7 1.9 3.9 2 1 2 4 4 4 0 TAFA family MLANA PF14991.6 KER27080.1 - 0.058 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A SKG6 PF08693.10 KER27080.1 - 0.28 10.6 1.7 0.51 9.8 1.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RVT_1 PF00078.27 KER27081.1 - 3.4e-37 128.1 0.0 6.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-binding PF00249.31 KER27081.1 - 2.9e-05 24.2 0.1 5.8e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KER27081.1 - 0.00078 19.3 0.2 0.0023 17.8 0.2 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Phage_Mu_Gam PF07352.12 KER27081.1 - 0.096 12.6 3.3 0.17 11.7 3.3 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1664 PF07889.12 KER27081.1 - 0.32 11.0 1.2 0.67 10.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.20 KER27082.1 - 1.6e-48 164.7 0.4 1.6e-48 164.7 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KER27082.1 - 8e-34 117.8 0.2 4e-19 69.7 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HMA PF00403.26 KER27082.1 - 1.9e-28 98.7 0.3 3.9e-09 36.8 0.5 5.4 5 1 0 5 5 5 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KER27082.1 - 0.00034 20.4 0.2 0.0038 17.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KER27082.1 - 0.014 15.5 0.0 1.3 9.2 0.0 3.4 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KER27082.1 - 0.015 15.7 0.1 0.42 11.0 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CBP4 PF07960.11 KER27082.1 - 0.18 11.6 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 CBP4 CwfJ_C_1 PF04677.15 KER27083.1 - 1.1e-25 89.9 0.0 2.2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KER27083.1 - 4.6e-18 65.9 0.0 1.3e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Oxysterol_BP PF01237.18 KER27084.1 - 6.7e-128 426.7 0.1 6.5e-116 387.2 0.0 3.3 3 0 0 3 3 3 3 Oxysterol-binding protein PH PF00169.29 KER27084.1 - 0.00018 22.0 0.1 0.00045 20.7 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KER27084.1 - 0.0017 18.6 0.1 0.0062 16.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Keratin PF02422.16 KER27084.1 - 0.033 13.9 0.8 0.083 12.6 0.0 2.1 2 0 0 2 2 2 0 Keratin PH_6 PF15406.6 KER27084.1 - 0.038 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Prefoldin PF02996.17 KER27084.1 - 0.076 12.9 4.9 0.067 13.1 0.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit Hrs_helical PF12210.8 KER27084.1 - 0.084 13.4 1.5 0.31 11.6 1.5 2.0 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CENP-F_leu_zip PF10473.9 KER27084.1 - 0.14 12.2 13.7 0.095 12.7 1.6 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 KER27084.1 - 1.3 9.7 5.0 20 5.9 1.3 2.8 2 0 0 2 2 2 0 SlyX Snapin_Pallidin PF14712.6 KER27084.1 - 4.1 7.9 9.0 0.19 12.2 0.9 2.6 3 0 0 3 3 3 0 Snapin/Pallidin DivIC PF04977.15 KER27084.1 - 4.1 7.2 6.8 0.78 9.6 0.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.15 KER27085.1 - 4.5e-27 94.1 0.7 8.2e-27 93.3 0.7 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KER27085.1 - 3.6e-20 71.8 2.0 5.1e-20 71.3 0.3 2.2 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 KER27085.1 - 0.0015 18.9 1.3 0.0015 18.9 1.3 1.6 2 0 0 2 2 2 1 Penicillinase repressor FapA PF03961.13 KER27085.1 - 0.0037 15.9 0.8 0.0052 15.4 0.8 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A FUR PF01475.19 KER27085.1 - 0.0047 17.1 0.4 0.0083 16.3 0.3 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family DUF745 PF05335.13 KER27085.1 - 0.089 12.5 4.7 0.13 12.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3103 PF11301.8 KER27085.1 - 0.31 9.8 4.0 0.41 9.4 3.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3103) MCC-bdg_PDZ PF10506.9 KER27085.1 - 0.37 10.9 4.2 1 9.4 0.4 2.6 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DivIC PF04977.15 KER27085.1 - 3.8 7.4 7.5 5.2 6.9 0.7 2.4 1 1 1 2 2 2 0 Septum formation initiator GIDA_assoc PF13932.6 KER27085.1 - 5 7.3 9.3 1.9 8.6 6.1 1.8 2 1 0 2 2 2 0 GidA associated domain Pep3_Vps18 PF05131.14 KER27086.1 - 4.4e-31 107.7 0.0 8.1e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KER27086.1 - 0.0046 16.8 0.1 0.062 13.2 0.0 2.9 4 0 0 4 4 4 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 KER27086.1 - 0.015 15.2 3.8 0.051 13.4 3.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER27086.1 - 0.02 14.9 2.0 0.06 13.3 2.0 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KER27086.1 - 0.021 14.6 1.2 0.021 14.6 1.2 2.1 2 0 0 2 2 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 KER27086.1 - 0.079 12.8 1.2 0.29 11.1 1.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER27086.1 - 0.093 12.8 1.1 0.32 11.1 1.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 KER27086.1 - 0.1 13.1 0.7 0.31 11.5 0.7 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 KER27086.1 - 0.22 11.8 1.8 0.84 10.0 1.8 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KER27086.1 - 0.25 11.7 3.7 1.3 9.5 3.7 2.3 1 1 0 1 1 1 0 Ring finger domain Snapin_Pallidin PF14712.6 KER27086.1 - 1.2 9.7 5.7 0.86 10.1 0.1 3.0 2 1 1 3 3 3 0 Snapin/Pallidin Pkinase_Tyr PF07714.17 KER27087.1 - 1.1e-53 182.1 0.0 1.6e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER27087.1 - 8.8e-43 146.6 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_KSR1 PF13543.6 KER27087.1 - 2.8e-06 27.5 0.1 4.5e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.6 KER27087.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER27087.1 - 0.0095 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER27087.1 - 0.19 11.6 0.2 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family C1_1 PF00130.22 KER27087.1 - 9.8 6.2 13.9 0.66 9.9 8.7 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ERCC4 PF02732.15 KER27089.1 - 3.8e-24 85.7 0.0 6.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain RPA_C PF08784.11 KER27089.1 - 0.00043 20.9 0.6 0.0012 19.4 0.1 2.1 2 0 0 2 2 2 1 Replication protein A C terminal Alg6_Alg8 PF03155.15 KER27092.1 - 2e-110 370.0 31.1 1.4e-89 301.3 22.3 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family RFXA_RFXANK_bdg PF15289.6 KER27093.1 - 1.7e-13 51.0 0.1 1.1e-12 48.3 0.1 2.0 1 1 0 1 1 1 1 Regulatory factor X-associated C-terminal binding domain DUF1279 PF06916.13 KER27094.1 - 0.091 13.3 0.2 0.14 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Ion_trans_2 PF07885.16 KER27096.1 - 6.5e-10 38.8 1.4 1.2e-09 38.0 1.4 1.4 1 0 0 1 1 1 1 Ion channel ANAPC4_WD40 PF12894.7 KER27097.1 - 1.5e-05 25.2 0.0 2.9 8.3 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER27097.1 - 0.032 15.1 7.1 10 7.2 2.1 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 KER27097.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DSL PF01414.19 KER27098.1 - 2e-09 37.6 4.2 2e-09 37.6 4.2 2.6 3 0 0 3 3 3 1 Delta serrate ligand zf-CCHC PF00098.23 KER27098.1 - 0.032 14.3 0.7 0.032 14.3 0.7 3.0 2 0 0 2 2 2 0 Zinc knuckle VIT PF08487.10 KER27099.1 - 7.9e-28 96.9 0.4 1.4e-27 96.1 0.4 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KER27099.1 - 1.5e-22 80.2 0.0 4.2e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KER27099.1 - 1.2e-12 47.5 0.2 9.5e-12 44.7 0.0 2.4 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KER27099.1 - 9.2e-10 39.1 0.0 2.5e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KER27099.1 - 1.3e-08 35.3 0.0 3.1e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KER27099.1 - 0.005 17.0 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus TMEM173 PF15009.6 KER27099.1 - 0.0098 15.1 0.1 0.09 11.9 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein 173 Arc_C PF18162.1 KER27100.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Arc C-lobe DUF4218 PF13960.6 KER27101.1 - 0.076 12.6 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Sas10_Utp3 PF04000.15 KER27102.1 - 2.5e-10 40.9 0.0 4.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MATH PF00917.26 KER27102.1 - 0.088 13.0 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 MATH domain DUF4330 PF14221.6 KER27104.1 - 0.23 11.7 0.0 0.36 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) EIF4E-T PF10477.9 KER27105.1 - 2.1e-05 23.6 7.0 2.1e-05 23.6 7.0 3.0 1 1 2 3 3 3 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PAT1 PF09770.9 KER27105.1 - 0.01 14.1 1.5 0.015 13.6 1.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bromodomain PF00439.25 KER27106.1 - 1.3e-88 291.2 11.7 3.8e-20 71.7 0.1 5.9 6 0 0 6 6 6 5 Bromodomain Asparaginase_2 PF01112.18 KER27106.1 - 8.2e-49 166.3 0.0 1.8e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Asparaginase BAH PF01426.18 KER27106.1 - 8.9e-23 80.5 0.0 2e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 BAH domain RVT_1 PF00078.27 KER27106.1 - 2.9e-12 46.6 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box PF00505.19 KER27106.1 - 7.7e-11 42.3 0.3 1.8e-10 41.1 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER27106.1 - 7.7e-10 39.2 1.6 2.1e-09 37.9 1.6 1.7 1 0 0 1 1 1 1 HMG-box domain PHD PF00628.29 KER27106.1 - 0.0025 17.7 6.3 0.0061 16.4 6.3 1.6 1 0 0 1 1 1 1 PHD-finger AT_hook PF02178.19 KER27106.1 - 1 9.5 7.6 4 7.6 7.6 2.1 1 0 0 1 1 1 0 AT hook motif Carb_anhydrase PF00194.21 KER27108.1 - 5.4e-22 78.5 0.0 5.9e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KER27110.1 - 4.9e-34 118.0 0.1 1.5e-30 106.6 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase Plasmo_rep PF12135.8 KER27110.1 - 0.35 10.5 4.5 8.4 6.0 0.3 2.4 2 0 0 2 2 2 0 Plasmodium repeat family RhoGAP PF00620.27 KER27115.1 - 2.9e-30 105.1 0.0 6.8e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain ESP PF16590.5 KER27115.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Exocrine gland-secreting peptide zf-BED PF02892.15 KER27115.1 - 0.42 10.7 3.6 6.5 6.9 0.2 2.7 2 0 0 2 2 2 0 BED zinc finger Gp_dh_C PF02800.20 KER27117.1 - 3.4e-69 231.5 0.0 5e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KER27117.1 - 3.2e-37 126.9 0.0 9.5e-37 125.4 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KER27117.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HNOB PF07700.15 KER27119.1 - 3.2e-73 245.1 4.4 2.6e-42 144.5 0.3 3.0 3 0 0 3 3 3 2 Haem-NO-binding Guanylate_cyc PF00211.20 KER27119.1 - 1.1e-47 162.0 1.6 2.3e-47 161.0 1.6 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KER27119.1 - 2.5e-47 161.2 11.7 3.4e-22 79.0 1.6 3.9 3 1 0 3 3 3 3 Heme NO binding associated DUF3455 PF11937.8 KER27119.1 - 0.12 12.8 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3455) P63C PF10546.9 KER27119.1 - 0.13 12.9 0.0 0.4 11.3 0.0 1.9 1 0 0 1 1 1 0 P63C domain Ion_trans PF00520.31 KER27122.1 - 2.9e-29 102.0 54.2 5e-26 91.4 29.9 2.4 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KER27122.1 - 6.1 5.4 24.6 2.8 6.5 6.7 3.7 2 1 1 3 3 3 0 Polycystin cation channel RT_RNaseH PF17917.1 KER27123.1 - 3.1e-25 88.5 0.1 9.3e-25 86.9 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER27123.1 - 1.1e-23 83.2 0.0 2.6e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KER27123.1 - 1.6e-20 73.5 0.0 3.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KER27123.1 - 1.2e-18 67.5 0.0 2.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KER27123.1 - 4.8e-14 52.2 0.3 1.7e-13 50.4 0.3 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain WD40 PF00400.32 KER27123.1 - 3.7e-12 46.6 0.1 3e-05 24.7 0.0 3.6 2 0 0 2 2 2 2 WD domain, G-beta repeat rve_3 PF13683.6 KER27123.1 - 7.4e-05 22.4 0.0 0.00025 20.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain ANAPC4_WD40 PF12894.7 KER27123.1 - 0.0089 16.3 0.0 0.038 14.3 0.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2 PF09337.10 KER27123.1 - 0.02 15.1 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 KER27123.1 - 0.026 14.8 0.1 0.1 12.9 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 KER27123.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Med30 PF11315.8 KER27124.1 - 1.6e-42 145.2 0.0 1.8e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 Syntaxin-6_N PF09177.11 KER27124.1 - 0.084 13.4 0.4 2.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Utp21 PF04192.12 KER27125.1 - 9.5e-22 77.6 0.2 2e-21 76.5 0.2 1.5 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KER27125.1 - 5.5e-05 23.9 10.4 8 7.5 0.1 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat Hira PF07569.11 KER27125.1 - 0.026 14.2 0.5 0.59 9.8 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split FliT PF05400.13 KER27125.1 - 0.062 14.1 2.9 11 6.9 0.2 2.5 2 0 0 2 2 2 0 Flagellar protein FliT fn3 PF00041.21 KER27129.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.9 1 1 0 1 1 1 0 Fibronectin type III domain Y_phosphatase PF00102.27 KER27130.1 - 1.9e-144 479.3 5.9 6.5e-74 248.4 0.3 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase fn3 PF00041.21 KER27130.1 - 1.3e-13 51.1 2.6 3.8e-07 30.3 0.9 4.9 5 0 0 5 5 5 3 Fibronectin type III domain Y_phosphatase3 PF13350.6 KER27130.1 - 1.9e-08 34.6 0.0 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 KER27130.1 - 7.6e-06 25.8 0.0 0.18 11.6 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KER27130.1 - 0.00019 21.6 0.8 0.72 9.9 0.0 3.8 5 0 0 5 5 5 2 Inositol hexakisphosphate fn3_4 PF16794.5 KER27130.1 - 0.012 15.6 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 0 Fibronectin-III type domain Y_phosphatase2 PF03162.13 KER27130.1 - 0.14 11.7 0.1 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Tyrosine phosphatase family TGF_beta PF00019.20 KER27131.1 - 2.6e-23 83.0 0.8 5.6e-23 81.9 0.8 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain Peptidase_C97 PF05903.14 KER27132.1 - 1.5e-18 67.0 0.1 3.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain EF-hand_7 PF13499.6 KER27133.1 - 7.4e-17 61.6 10.2 3e-09 37.2 5.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER27133.1 - 1.3e-11 43.2 16.9 3.6e-05 23.0 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KER27133.1 - 1.6e-10 40.6 5.6 2.3e-07 30.6 3.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER27133.1 - 3.4e-10 39.0 15.4 1.4e-05 24.6 0.2 5.0 5 1 1 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 KER27133.1 - 0.00042 19.7 8.6 0.0017 17.8 0.2 3.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 KER27133.1 - 0.00091 19.5 1.3 0.0034 17.7 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain DUF1948 PF09185.10 KER27133.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) EF-hand_4 PF12763.7 KER27133.1 - 1.1 9.2 4.1 1.5 8.8 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-TRAF PF02176.18 KER27135.1 - 0.00014 22.5 1.6 0.00014 22.5 1.6 3.2 3 1 0 3 3 3 1 TRAF-type zinc finger Sina PF03145.16 KER27135.1 - 0.00023 21.2 3.2 0.00046 20.2 3.2 1.5 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 KER27135.1 - 0.00049 19.9 10.6 0.00049 19.9 10.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KER27135.1 - 0.0093 15.7 9.9 0.0093 15.7 9.9 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 KER27135.1 - 0.24 11.8 4.6 0.49 10.8 3.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KER27135.1 - 0.7 9.9 17.3 0.065 13.2 12.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KER27135.1 - 1.3 9.0 15.4 0.064 13.1 9.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KER27135.1 - 2 8.3 20.1 0.71 9.8 13.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med9 PF07544.13 KER27137.1 - 0.068 13.3 0.7 0.068 13.3 0.7 4.2 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 KER27137.1 - 0.43 11.0 0.1 0.43 11.0 0.1 3.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KER27137.1 - 0.85 9.7 31.9 0.36 10.9 11.2 3.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 KER27137.1 - 3 7.8 18.6 2.7 7.9 0.1 4.7 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PspB PF06667.12 KER27137.1 - 6.9 6.8 18.9 0.21 11.6 1.1 3.8 3 1 0 3 3 3 0 Phage shock protein B DUF445 PF04286.12 KER27137.1 - 8 6.2 11.4 17 5.1 11.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Hormone_3 PF00159.18 KER27139.1 - 0.00031 20.7 1.0 0.00048 20.2 1.0 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide tRNA-synt_1g PF09334.11 KER27141.1 - 1.3e-33 116.3 0.1 2.4e-28 99.0 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (M) NAD_binding_5 PF07994.12 KER27141.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase tRNA-synt_1g PF09334.11 KER27142.1 - 6.3e-34 117.4 0.0 8.3e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KER27142.1 - 7.3e-05 21.2 0.0 8.5e-05 21.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KER27142.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KER27142.1 - 0.054 12.8 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CCSMST1 PF15013.6 KER27143.1 - 2.1e-11 43.8 0.0 4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 CCSMST1 family Tagatose_6_P_K PF08013.11 KER27144.1 - 0.071 11.8 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase UCH PF00443.29 KER27145.1 - 5.1e-40 137.6 0.0 1.4e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER27145.1 - 1.1e-06 28.5 1.1 0.22 11.1 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUF3381 PF11861.8 KER27145.1 - 0.022 14.5 1.2 0.072 12.9 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) ETX_MTX2 PF03318.13 KER27146.1 - 0.0033 17.2 0.2 0.071 12.9 0.0 2.8 3 0 0 3 3 3 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Spore_YtrH PF14034.6 KER27146.1 - 0.013 15.6 0.0 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YtrH Methyltransf_15 PF09445.10 KER27146.1 - 0.096 12.3 0.0 18 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase GEN1_C PF18380.1 KER27146.1 - 0.13 13.1 0.7 25 5.8 0.0 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain INCENP_ARK-bind PF03941.15 KER27146.1 - 0.27 11.2 2.1 22 5.1 0.2 2.5 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Tom5 PF10642.9 KER27146.1 - 0.68 10.0 3.5 24 5.1 0.3 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase RPA_interact_C PF14768.6 KER27147.1 - 2.2e-17 63.4 4.6 5.6e-17 62.1 4.6 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal CREPT PF16566.5 KER27148.1 - 1.5e-40 138.7 2.7 2.4e-40 138.1 2.7 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour GCP_N_terminal PF17681.1 KER27148.1 - 0.012 15.3 1.7 0.015 14.9 1.4 1.3 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal FH2 PF02181.23 KER27148.1 - 0.014 14.5 2.4 0.017 14.3 2.4 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain MCD_N PF17408.2 KER27148.1 - 0.039 14.1 3.2 0.16 12.1 0.5 2.9 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF1664 PF07889.12 KER27148.1 - 0.039 14.0 1.8 0.087 12.9 0.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF5517 PF17639.2 KER27148.1 - 0.061 13.6 0.4 0.15 12.3 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5517) Seryl_tRNA_N PF02403.22 KER27148.1 - 0.072 13.3 7.4 0.18 12.1 5.6 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Lectin_N PF03954.14 KER27148.1 - 0.078 12.7 4.1 0.079 12.7 2.6 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain CdvA PF18822.1 KER27148.1 - 0.26 11.1 6.1 0.058 13.2 2.4 1.8 2 1 0 2 2 2 0 CdvA-like coiled-coil domain HMMR_N PF15905.5 KER27148.1 - 0.33 10.4 8.3 0.29 10.6 5.5 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FliT PF05400.13 KER27148.1 - 0.36 11.7 8.7 8.1 7.3 4.0 2.5 2 1 0 2 2 2 0 Flagellar protein FliT UPF0242 PF06785.11 KER27148.1 - 0.54 10.3 8.9 0.28 11.3 6.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KER27148.1 - 0.65 10.2 11.5 1.6 8.9 11.0 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V-SNARE PF05008.15 KER27148.1 - 1.8 9.0 9.3 5.9 7.3 0.7 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Swi5 PF07061.11 KER27148.1 - 2 8.6 7.0 1e+02 3.1 7.0 3.0 1 1 0 1 1 1 0 Swi5 FUSC PF04632.12 KER27148.1 - 2.5 6.5 5.2 3.7 6.0 4.9 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Topoisom_bac PF01131.20 KER27149.1 - 1.5e-95 320.7 0.0 1.3e-76 258.3 0.0 2.0 2 0 0 2 2 2 2 DNA topoisomerase zf-GRF PF06839.12 KER27149.1 - 3.2e-29 100.8 9.7 1.8e-14 53.6 1.2 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 KER27149.1 - 4e-16 59.1 0.0 8.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain RVT_1 PF00078.27 KER27149.1 - 4.6e-08 32.9 0.0 4.5e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4_Topoisom PF01396.19 KER27149.1 - 3e-05 23.7 8.5 0.008 15.9 0.1 4.6 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 KER27149.1 - 0.019 14.7 3.0 0.059 13.1 3.0 1.8 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KER27149.1 - 0.26 11.5 2.5 1.2 9.4 2.5 2.3 1 0 0 1 1 1 0 Zinc knuckle DZR PF12773.7 KER27149.1 - 0.64 10.1 8.0 9.9 6.3 0.1 4.3 4 0 0 4 4 4 0 Double zinc ribbon HORMA PF02301.18 KER27150.1 - 1.1e-18 67.6 2.5 1.4e-18 67.3 0.0 2.4 3 1 1 4 4 4 1 HORMA domain PHD PF00628.29 KER27150.1 - 5.2e-08 32.7 6.9 1.2e-07 31.5 6.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KER27150.1 - 0.00097 18.6 3.1 0.002 17.6 3.1 1.6 1 0 0 1 1 1 1 PHD-finger Ribosomal_S25 PF03297.15 KER27150.1 - 0.0041 17.3 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 S25 ribosomal protein PHD_3 PF13922.6 KER27150.1 - 0.25 11.8 2.9 0.8 10.1 2.9 2.0 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Vps35 PF03635.17 KER27151.1 - 3.8e-226 753.0 0.0 5.2e-226 752.6 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RPW8 PF05659.11 KER27151.1 - 0.097 12.4 0.3 0.88 9.3 0.1 2.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DEAD PF00270.29 KER27153.1 - 1.8e-23 83.2 0.0 3.4e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RVT_1 PF00078.27 KER27153.1 - 1.8e-18 66.9 0.0 4.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 KER27153.1 - 3.1e-17 62.9 0.1 1.1e-16 61.1 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Integrase_H2C2 PF17921.1 KER27153.1 - 2.3e-15 56.4 0.0 5.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KER27153.1 - 1.6e-05 25.0 0.1 3.5e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger AAA_22 PF13401.6 KER27153.1 - 0.0041 17.4 0.4 0.011 16.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain Helicase_C_4 PF13871.6 KER27153.1 - 0.074 12.7 0.3 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain on Strawberry notch homologue CR6_interact PF10147.9 KER27155.1 - 2.5e-26 92.7 9.6 3e-26 92.4 9.6 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RVT_1 PF00078.27 KER27155.1 - 0.0006 19.4 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin-6_N PF09177.11 KER27155.1 - 0.32 11.6 5.5 1.7 9.2 2.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Tox-REase-5 PF15648.6 KER27155.1 - 4.3 7.9 6.5 17 6.0 0.4 2.4 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 5 WD40 PF00400.32 KER27156.1 - 9.9e-29 99.0 14.4 1.8e-06 28.6 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KER27156.1 - 1.2e-27 95.9 2.8 4e-27 94.3 0.3 3.1 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KER27156.1 - 0.00025 21.3 1.5 0.2 12.0 0.0 3.8 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 KER27159.1 - 1.9e-08 34.3 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER27159.1 - 8.6e-06 26.3 0.0 4.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER27159.1 - 0.00014 22.6 0.0 0.00094 19.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER27159.1 - 0.0063 17.2 0.0 0.071 13.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER27159.1 - 0.049 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KER27159.1 - 0.064 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 KER27159.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family fn3 PF00041.21 KER27160.1 - 5e-11 42.8 7.2 0.027 14.8 0.0 5.3 5 0 0 5 5 5 5 Fibronectin type III domain DUF4998 PF16389.5 KER27160.1 - 0.081 12.5 0.4 18 4.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function Bystin PF05291.11 KER27161.1 - 1.4e-41 142.7 0.2 2.2e-41 142.1 0.2 1.2 1 0 0 1 1 1 1 Bystin Exo_endo_phos_2 PF14529.6 KER27161.1 - 4.2e-06 26.6 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Pkinase PF00069.25 KER27162.1 - 5.8e-26 91.4 0.0 3.2e-24 85.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27162.1 - 1e-14 54.4 0.0 1.3e-13 50.8 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER27162.1 - 1.9e-05 23.6 0.5 4.3e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KER27162.1 - 0.00093 19.2 0.1 0.01 15.8 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Tctex-1 PF03645.13 KER27163.1 - 2.8e-08 33.9 1.6 8.6e-08 32.4 1.6 1.9 1 1 0 1 1 1 1 Tctex-1 family Ank_4 PF13637.6 KER27164.1 - 2.9e-11 43.7 0.1 0.031 14.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER27164.1 - 5.1e-06 26.4 0.4 0.17 12.6 0.3 4.8 4 1 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KER27164.1 - 1.1e-05 25.9 0.5 0.028 15.0 0.3 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER27164.1 - 2e-05 24.8 2.8 0.14 12.6 0.2 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KER27164.1 - 0.00032 20.9 2.7 0.073 13.4 1.2 3.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) RGS PF00615.19 KER27166.1 - 2.9e-28 98.5 4.3 8.8e-16 58.2 0.1 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain Ribosomal_L24e PF01246.20 KER27167.1 - 2.1e-26 91.9 0.6 2.1e-26 91.9 0.6 2.6 2 1 0 2 2 2 1 Ribosomal protein L24e Hydin_ADK PF17213.3 KER27167.1 - 5.3 7.3 9.0 7 6.9 9.0 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_LBD PF02931.23 KER27170.1 - 1.3e-55 188.2 0.6 2.4e-55 187.3 0.6 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER27170.1 - 1.5e-13 51.4 7.2 3.2e-05 24.1 1.8 3.2 3 0 0 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Integrase_H2C2 PF17921.1 KER27171.1 - 0.056 13.6 1.3 0.079 13.1 0.1 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain Histone PF00125.24 KER27172.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER27172.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER27172.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KER27172.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 KER27172.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Histone_H2A_C PF16211.5 KER27173.1 - 8.2e-21 73.4 1.4 1.3e-20 72.8 1.4 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KER27173.1 - 2.6e-15 57.0 0.0 3.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER27173.1 - 8.4e-06 26.0 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KER27174.1 - 4.5e-08 33.2 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KER27174.1 - 6.6e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KER27174.1 - 0.00012 22.3 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KER27174.1 - 0.00033 21.0 0.1 0.00053 20.3 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER27174.1 - 0.0008 19.6 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KER27174.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KER27174.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DAO PF01266.24 KER27177.1 - 7.5e-08 32.3 0.0 9.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase F5_F8_type_C PF00754.25 KER27178.1 - 9.8e-53 177.6 4.8 2.4e-21 76.2 0.0 4.4 3 1 1 4 4 4 4 F5/8 type C domain Tim17 PF02466.19 KER27179.1 - 2e-24 86.1 3.7 2e-24 86.1 3.7 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Fz PF01392.22 KER27181.1 - 4e-28 98.3 4.3 9.4e-28 97.1 4.3 1.7 1 0 0 1 1 1 1 Fz domain Mid1 PF12929.7 KER27181.1 - 1.3 8.2 5.5 0.72 9.0 2.6 1.8 1 1 1 2 2 2 0 Stretch-activated Ca2+-permeable channel component MGAT2 PF05060.14 KER27182.1 - 3.6e-90 302.6 0.0 4.8e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) RAWUL PF16207.5 KER27183.1 - 8.6e-11 42.4 0.1 1.7e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KER27183.1 - 9.3e-10 38.2 9.3 1.9e-09 37.2 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER27183.1 - 3.1e-08 33.3 10.2 8.4e-08 32.0 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER27183.1 - 1.8e-06 28.1 8.5 5.8e-06 26.5 8.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER27183.1 - 3.5e-05 23.6 7.3 7.9e-05 22.4 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER27183.1 - 0.00017 21.5 3.5 0.00017 21.5 3.5 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KER27183.1 - 0.00028 21.0 7.1 0.00028 21.0 7.1 3.0 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KER27183.1 - 0.00064 19.6 8.5 0.00064 19.6 8.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KER27183.1 - 0.00073 19.8 4.9 0.0021 18.3 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KER27183.1 - 0.0021 18.1 4.7 0.0044 17.1 4.7 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KER27183.1 - 0.0099 15.7 8.4 0.024 14.5 8.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Atg8 PF02991.16 KER27183.1 - 0.082 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like zf-Nse PF11789.8 KER27183.1 - 0.086 12.7 5.6 0.23 11.3 5.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Coilin_N PF15862.5 KER27183.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Coilin N-terminus zf-RING_6 PF14835.6 KER27183.1 - 0.44 10.4 7.0 0.22 11.4 4.5 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KER27183.1 - 0.47 10.6 4.3 1.1 9.4 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Fer4 PF00037.27 KER27189.1 - 1.2e-11 43.9 13.4 8.4e-09 34.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KER27189.1 - 2.4e-11 44.0 7.4 3.6e-11 43.5 7.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KER27189.1 - 8.1e-11 42.7 3.3 1.6e-05 25.7 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KER27189.1 - 7.4e-08 32.4 17.1 0.00013 22.0 9.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KER27189.1 - 8.9e-08 32.2 7.2 1.4e-07 31.6 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KER27189.1 - 4.6e-07 30.2 1.0 9.9e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KER27189.1 - 4.3e-06 26.6 14.0 0.0073 16.3 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KER27189.1 - 3.9e-05 23.7 9.0 0.0031 17.6 1.7 2.1 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KER27189.1 - 0.00019 21.7 7.6 0.081 13.5 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KER27189.1 - 0.00037 20.4 9.1 0.0013 18.7 2.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 KER27189.1 - 0.011 16.3 8.7 0.16 12.5 9.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KER27189.1 - 0.019 15.5 5.9 0.05 14.2 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KER27189.1 - 0.079 13.9 12.4 0.18 12.8 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KER27189.1 - 0.46 10.6 2.5 1.1 9.5 2.5 1.5 1 1 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 KER27189.1 - 0.68 10.1 6.9 0.84 9.8 1.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KER27189.1 - 4.2 8.3 8.2 1.3 9.9 1.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain T-box PF00907.22 KER27191.1 - 1.2e-81 273.4 1.3 2.1e-81 272.6 1.3 1.4 1 0 0 1 1 1 1 T-box Porin_3 PF01459.22 KER27194.1 - 8.5e-54 182.8 1.5 9.7e-54 182.6 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin HmuY PF14064.6 KER27194.1 - 0.043 14.0 0.6 1.5 9.0 0.6 2.2 1 1 0 1 1 1 0 HmuY protein 7tm_1 PF00001.21 KER27195.1 - 1.9e-12 47.1 14.0 9.6e-12 44.8 14.0 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER27195.1 - 5.2e-12 45.7 4.5 7.9e-12 45.1 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KER27195.1 - 0.0045 16.7 2.0 0.0045 16.7 2.0 3.4 3 1 1 4 4 4 2 Serpentine type 7TM GPCR chemoreceptor Srx COX16 PF14138.6 KER27195.1 - 0.07 13.7 0.3 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF2452 PF10504.9 KER27197.1 - 0.046 13.2 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) CLPTM1 PF05602.12 KER27200.1 - 3.7e-76 256.9 0.1 4.4e-76 256.6 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KER27200.1 - 0.037 13.8 0.2 3.7 7.4 0.0 2.9 2 0 0 2 2 2 0 PQ loop repeat Nop PF01798.18 KER27202.1 - 1e-79 267.2 0.3 1e-79 267.2 0.3 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KER27202.1 - 4.7e-18 65.3 0.7 1.1e-17 64.2 0.7 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain ASC PF00858.24 KER27203.1 - 8.8e-49 166.6 0.0 1.2e-48 166.2 0.0 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ApoO PF09769.9 KER27203.1 - 0.12 12.4 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O Cadherin PF00028.17 KER27206.1 - 3.6e-64 213.2 5.7 5.5e-12 46.0 0.0 9.9 8 3 0 9 9 9 7 Cadherin domain Cadherin_2 PF08266.12 KER27206.1 - 1.3e-06 28.1 0.0 0.00069 19.4 0.0 4.1 4 0 0 4 4 4 1 Cadherin-like RET_CLD1 PF17756.1 KER27206.1 - 0.0079 16.5 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 RET Cadherin like domain 1 Cadherin_3 PF16184.5 KER27206.1 - 3.2 7.8 5.9 29 4.7 0.0 5.0 6 1 0 6 6 6 0 Cadherin-like DNase_II PF03265.15 KER27207.1 - 1.2e-79 267.9 0.0 1.4e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II PQQ_2 PF13360.6 KER27211.1 - 0.25 10.9 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain BTB PF00651.31 KER27212.1 - 1.9e-18 66.7 0.1 6.7e-18 65.0 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain PHR PF08005.12 KER27212.1 - 4e-12 47.0 0.2 1.1e-05 26.2 0.0 3.5 3 0 0 3 3 3 2 PHR domain BACK PF07707.15 KER27212.1 - 3.2e-08 33.6 0.0 7.1e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2 PF00096.26 KER27213.1 - 1.5e-07 31.4 13.2 0.0018 18.6 3.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER27213.1 - 2.4e-05 24.8 11.4 0.025 15.4 2.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER27213.1 - 4.7e-05 23.6 9.5 0.00054 20.3 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER27213.1 - 0.013 15.8 3.4 1.3 9.4 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4379 PF14311.6 KER27213.1 - 0.015 15.6 0.9 0.047 14.1 0.9 1.8 1 0 0 1 1 1 0 Probable Zinc-ribbon domain zf-C2H2_6 PF13912.6 KER27213.1 - 0.018 15.0 6.2 0.26 11.3 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER27213.1 - 0.17 12.2 1.4 0.47 10.8 1.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KER27213.1 - 0.26 11.7 3.0 0.49 10.9 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ATPase-cat_bd PF12156.8 KER27213.1 - 0.43 11.4 2.0 0.84 10.4 2.0 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Zn-ribbon_8 PF09723.10 KER27213.1 - 0.43 10.7 4.0 0.92 9.7 2.8 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 KER27213.1 - 9.5 6.1 7.5 0.5 10.2 1.0 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF3449 PF11931.8 KER27214.1 - 1.5e-73 246.5 0.0 3.4e-73 245.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 KER27214.1 - 3.9e-26 90.5 1.2 1e-25 89.2 1.2 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 KER27214.1 - 1e-23 83.6 1.3 3.2e-23 82.0 1.3 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KER27214.1 - 6.2e-14 51.6 0.7 6.2e-14 51.6 0.7 2.4 3 0 0 3 3 3 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KER27214.1 - 0.0022 18.3 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PI-PLC-C1 PF16670.5 KER27214.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent FHA PF00498.26 KER27215.1 - 3.5e-14 52.9 0.0 1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 FHA domain Dicer_dimer PF03368.14 KER27215.1 - 6.3e-05 23.1 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.26 KER27215.1 - 0.0014 19.3 0.5 0.021 15.5 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif CCDC-167 PF15188.6 KER27215.1 - 0.0047 17.2 1.4 0.013 15.8 1.4 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 KER27215.1 - 0.056 13.7 0.8 0.19 12.0 0.8 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain VGCC_alpha2 PF08473.11 KER27215.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd DNA_pol_E_B PF04042.16 KER27216.1 - 8.6e-28 97.1 0.1 3.7e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 KER27216.1 - 2.2e-12 47.1 0.1 3.8e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal UreE_N PF02814.15 KER27216.1 - 0.00032 20.2 0.4 0.00067 19.2 0.4 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain DUF4218 PF13960.6 KER27217.1 - 6.3e-06 25.8 0.1 7.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Ras PF00071.22 KER27218.1 - 5.1e-23 81.5 0.0 6e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER27218.1 - 1.8e-08 34.6 0.0 8.8e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER27218.1 - 5.8e-08 32.4 0.0 6.6e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER27218.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 KER27218.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TBP PF00352.21 KER27219.1 - 1.5e-62 207.5 0.1 8.7e-31 105.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KER27219.1 - 0.00041 20.4 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Septin PF00735.18 KER27220.1 - 5.1e-89 298.3 0.0 9.1e-89 297.5 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KER27220.1 - 7.2e-06 26.1 0.0 2.1e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fez1 PF06818.15 KER27220.1 - 1.2e-05 25.9 13.0 2.5e-05 24.8 13.0 1.4 1 0 0 1 1 1 1 Fez1 FapA PF03961.13 KER27220.1 - 0.00012 20.9 0.5 0.00021 20.0 0.5 1.3 1 0 0 1 1 1 1 Flagellar Assembly Protein A FtsK_SpoIIIE PF01580.18 KER27220.1 - 0.0028 17.0 1.8 0.0032 16.9 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family FAM184 PF15665.5 KER27220.1 - 0.0086 15.9 11.9 0.0086 15.9 11.9 1.6 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B AIG1 PF04548.16 KER27220.1 - 0.045 13.1 2.7 0.051 12.9 0.0 2.2 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 KER27220.1 - 0.047 13.6 1.1 0.38 10.6 0.1 2.6 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KER27220.1 - 0.049 13.7 3.3 1.2 9.1 0.1 3.3 3 0 0 3 3 3 0 Dynamin family DUF4800 PF16057.5 KER27220.1 - 0.052 12.8 4.0 0.091 12.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) MeaB PF03308.16 KER27220.1 - 0.055 12.5 2.6 0.14 11.1 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Exonuc_VII_L PF02601.15 KER27220.1 - 0.06 12.9 3.4 0.11 12.1 3.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_16 PF13191.6 KER27220.1 - 0.075 13.4 0.3 0.29 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KER27220.1 - 0.092 12.6 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 KER27220.1 - 0.19 12.0 0.4 0.65 10.3 0.0 2.1 3 0 0 3 3 1 0 AAA domain DUF1043 PF06295.12 KER27220.1 - 0.49 10.4 4.8 1.1 9.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Atg14 PF10186.9 KER27220.1 - 2.7 7.0 7.8 4.7 6.2 7.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fungal_TACC PF12709.7 KER27220.1 - 4.1 7.9 8.5 1.8 9.1 4.4 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PMI_typeI PF01238.21 KER27221.1 - 3.7e-101 339.0 0.0 4.7e-101 338.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I ChaB PF06150.12 KER27222.1 - 0.049 14.2 0.0 0.062 13.9 0.0 1.1 1 0 0 1 1 1 0 ChaB tRNA_anti-codon PF01336.25 KER27223.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Kinesin PF00225.23 KER27224.1 - 7.5e-93 311.1 0.1 2e-92 309.7 0.1 1.8 1 1 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KER27224.1 - 2.4e-45 154.9 9.6 3.3e-35 121.9 1.7 3.7 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 KER27224.1 - 1.7e-38 132.7 0.0 7.4e-38 130.6 0.0 2.2 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 KER27224.1 - 4.4e-18 65.6 0.0 1.3e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KER27224.1 - 0.0024 18.4 0.2 0.012 16.2 0.0 2.4 2 0 0 2 2 2 1 PH domain RGS PF00615.19 KER27225.1 - 4.7e-33 114.0 4.1 8e-33 113.2 4.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C1 PF00112.23 KER27227.1 - 2.5e-61 207.6 2.3 3e-61 207.3 2.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KER27227.1 - 4.6e-11 42.4 0.0 9.9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KER27227.1 - 0.0026 16.6 0.6 1 8.0 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Ribosomal_L13e PF01294.18 KER27228.1 - 4.9e-74 248.1 8.4 6e-74 247.8 8.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Dpy-30 PF05186.13 KER27229.1 - 3.2e-10 39.5 0.3 4.5e-09 35.9 0.1 2.3 2 0 0 2 2 2 1 Dpy-30 motif ADK PF00406.22 KER27229.1 - 8.4e-10 38.9 0.1 2.1e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 KER27229.1 - 1.2e-08 35.5 0.4 0.00042 20.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KER27229.1 - 0.00028 21.4 0.0 0.0033 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KER27229.1 - 0.00033 21.1 0.0 0.00095 19.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER27229.1 - 0.00051 20.3 0.7 0.0044 17.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KER27229.1 - 0.0017 18.6 0.0 0.063 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KER27229.1 - 0.0029 18.0 1.4 0.01 16.2 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KER27229.1 - 0.023 14.9 0.0 0.091 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KER27229.1 - 0.025 14.6 0.0 0.089 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glycos_transf_2 PF00535.26 KER27229.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Hydin_ADK PF17213.3 KER27229.1 - 0.036 14.3 0.2 0.08 13.2 0.0 1.7 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain IstB_IS21 PF01695.17 KER27229.1 - 0.038 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KER27229.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KER27229.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KER27229.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NIF PF03031.18 KER27230.1 - 3.5e-33 114.6 0.0 6e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RVT_1 PF00078.27 KER27230.1 - 4.9e-14 52.4 0.0 7.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KER27231.1 - 3.2e-14 53.1 0.0 6.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER27231.1 - 1.7e-05 24.5 0.0 4.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PH PF00169.29 KER27234.1 - 0.00027 21.4 0.0 0.00038 20.9 0.0 1.3 1 0 0 1 1 1 1 PH domain RNA_pol_A_bac PF01000.26 KER27235.1 - 4.9e-32 110.6 0.0 1.4e-31 109.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KER27235.1 - 1.3e-17 62.9 0.0 2.8e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Exo_endo_phos PF03372.23 KER27235.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family B56 PF01603.20 KER27237.1 - 4.5e-165 549.6 5.4 4.6e-131 437.6 4.4 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KER27237.1 - 0.054 13.4 2.9 0.64 9.9 0.2 2.5 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NFRKB_winged PF14465.6 KER27239.1 - 1.1e-08 35.2 0.0 7.5e-08 32.5 0.0 2.4 2 1 0 2 2 2 1 NFRKB Winged Helix-like zf-CCCH PF00642.24 KER27240.1 - 5.4e-12 45.3 15.7 7e-08 32.2 2.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER27240.1 - 1.7e-06 27.7 24.6 0.00039 20.2 4.5 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KER27240.1 - 7.2e-06 26.3 15.5 0.012 16.1 3.6 2.9 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KER27240.1 - 0.00014 21.8 19.7 0.029 14.4 8.1 2.9 2 1 0 2 2 2 2 Zinc finger domain PAC4 PF16093.5 KER27240.1 - 0.035 14.3 0.5 0.13 12.5 0.5 1.9 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Torus PF16131.5 KER27240.1 - 1.9 9.2 9.9 1.1 9.9 1.2 2.7 1 1 1 2 2 2 0 Torus domain Ig_3 PF13927.6 KER27241.1 - 3.1e-49 165.5 4.3 6.5e-11 42.7 0.0 11.9 10 3 0 10 10 10 7 Immunoglobulin domain fn3 PF00041.21 KER27241.1 - 7.3e-46 154.4 14.2 1.1e-12 48.1 0.5 8.5 7 2 0 7 7 7 6 Fibronectin type III domain I-set PF07679.16 KER27241.1 - 2.2e-39 133.4 0.5 9e-08 32.1 0.0 12.7 12 1 0 12 12 12 7 Immunoglobulin I-set domain Ig_2 PF13895.6 KER27241.1 - 3.1e-29 101.1 0.0 0.0001 22.6 0.0 10.5 10 1 0 10 10 10 6 Immunoglobulin domain ig PF00047.25 KER27241.1 - 1.9e-19 69.6 8.2 0.00016 21.8 0.0 10.8 11 2 0 11 11 11 3 Immunoglobulin domain V-set PF07686.17 KER27241.1 - 2.5e-19 69.5 4.2 0.00023 21.3 0.0 9.6 8 2 0 9 9 9 4 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KER27241.1 - 7.7e-09 36.0 3.4 0.15 12.7 0.2 6.0 5 1 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 KER27241.1 - 8.2e-06 25.3 0.0 0.21 11.2 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 KER27241.1 - 0.023 15.0 0.0 43 4.5 0.0 4.1 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 KER27241.1 - 0.04 14.0 0.1 4.7 7.4 0.0 4.0 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Interfer-bind PF09294.10 KER27241.1 - 0.073 13.4 0.0 0.33 11.3 0.0 2.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III OxoDH_E1alpha_N PF12573.8 KER27243.1 - 0.27 11.0 2.8 0.66 9.8 2.8 1.6 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Neur_chan_LBD PF02931.23 KER27244.1 - 7.6e-59 198.8 2.0 7.6e-59 198.8 2.0 1.9 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER27244.1 - 1.7e-34 119.9 3.8 5.1e-34 118.4 3.8 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SecA_DEAD PF07517.14 KER27245.1 - 1.1e-37 130.0 0.0 6.8e-35 120.8 0.0 2.4 2 0 0 2 2 2 2 SecA DEAD-like domain SecA_PP_bind PF01043.20 KER27245.1 - 2.2e-16 60.5 2.2 1.1e-08 35.8 0.0 3.9 4 0 0 4 4 2 2 SecA preprotein cross-linking domain TPR_2 PF07719.17 KER27245.1 - 2.7e-08 33.3 3.8 0.013 15.5 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Helicase_C PF00271.31 KER27245.1 - 4.3e-07 30.3 1.2 0.025 14.9 0.1 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain TPR_11 PF13414.6 KER27245.1 - 4.7e-05 23.0 12.5 0.017 14.8 0.6 3.7 4 0 0 4 4 4 2 TPR repeat RHS PF03527.14 KER27245.1 - 0.00022 20.9 0.0 1.6 8.6 0.0 3.0 2 0 0 2 2 2 2 RHS protein DUF148 PF02520.17 KER27245.1 - 0.00054 20.0 0.4 4.5 7.4 0.0 4.2 2 2 2 4 4 4 2 Domain of unknown function DUF148 TPR_1 PF00515.28 KER27245.1 - 0.0012 18.5 9.4 0.35 10.8 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C48 PF02902.19 KER27245.1 - 0.011 15.6 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF2859 PF11072.8 KER27245.1 - 0.014 15.1 0.1 11 5.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) DUF3638 PF12340.8 KER27245.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Serine_rich PF08824.10 KER27245.1 - 0.016 15.2 1.0 14 5.6 0.1 3.8 2 0 0 2 2 2 0 Serine rich protein interaction domain ResIII PF04851.15 KER27245.1 - 0.023 14.7 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KER27245.1 - 0.057 12.8 0.3 50 3.1 0.0 3.7 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 KER27245.1 - 0.076 13.1 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain rve PF00665.26 KER27245.1 - 0.12 12.6 0.1 38 4.5 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain TPR_17 PF13431.6 KER27245.1 - 0.13 12.7 1.9 1.4e+02 3.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1474 PF07342.11 KER27245.1 - 0.44 11.1 3.7 37 4.9 0.1 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF1474) DUF5623 PF18536.1 KER27245.1 - 0.66 10.3 2.6 46 4.3 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) TPR_12 PF13424.6 KER27245.1 - 1.4 9.3 8.5 29 5.0 1.0 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TelA PF05816.11 KER27245.1 - 1.7 7.6 5.5 13 4.7 0.5 2.4 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Porin_7 PF16956.5 KER27246.1 - 0.029 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative general bacterial porin Peptidase_S24 PF00717.23 KER27247.1 - 1.2e-09 38.0 0.1 2e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Mem_trans PF03547.18 KER27251.1 - 7e-14 51.0 3.7 7e-14 51.0 3.7 2.0 2 0 0 2 2 2 2 Membrane transport protein TMEM169 PF15052.6 KER27251.1 - 2.5 8.2 8.2 0.19 11.9 1.0 2.5 2 1 0 2 2 2 0 TMEM169 protein family TB2_DP1_HVA22 PF03134.19 KER27254.1 - 1.1e-20 73.3 1.0 2.6e-20 72.1 1.0 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4590 PF15257.6 KER27255.1 - 4.1e-33 113.7 0.3 9.6e-33 112.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) RTP PF02334.16 KER27259.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 Replication terminator protein GIY-YIG PF01541.24 KER27260.1 - 0.001 19.3 0.1 0.0023 18.2 0.1 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain DSL PF01414.19 KER27260.1 - 0.094 13.0 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Delta serrate ligand SDA1 PF05285.12 KER27261.1 - 0.00049 19.6 48.0 0.00088 18.8 48.0 1.4 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 KER27261.1 - 0.028 13.8 46.3 0.039 13.3 46.3 1.3 1 0 0 1 1 1 0 BUD22 Neur_chan_LBD PF02931.23 KER27262.1 - 1.1e-60 204.8 3.1 1.1e-60 204.8 3.1 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER27262.1 - 3.2e-53 181.3 1.5 8.7e-53 179.8 1.5 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region HP0268 PF18618.1 KER27264.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 HP0268 Ashwin PF15323.6 KER27265.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.5 1 1 1 2 2 2 0 Developmental protein SCAPER_N PF16501.5 KER27266.1 - 7.1e-30 102.9 0.5 1.8e-29 101.6 0.5 1.7 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 KER27266.1 - 1e-05 25.7 1.9 1e-05 25.7 1.9 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER27266.1 - 0.19 12.1 4.0 0.13 12.6 1.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Frizzled PF01534.17 KER27267.1 - 1.3e-111 372.8 7.1 1.1e-85 287.5 0.2 2.1 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region CoA_binding_3 PF13727.6 KER27267.1 - 3.1 7.8 20.3 9.6 6.2 0.0 3.9 3 1 1 4 4 4 0 CoA-binding domain bVLRF1 PF18826.1 KER27268.1 - 7e-34 116.8 0.0 4.7e-28 97.9 0.0 2.6 2 0 0 2 2 2 2 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 KER27268.1 - 0.00021 21.8 0.0 0.00063 20.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KER27268.1 - 0.0011 19.3 0.0 0.0041 17.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KER27268.1 - 0.0016 18.8 0.0 0.026 15.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KER27268.1 - 0.0017 18.6 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER27268.1 - 0.0021 18.6 0.0 0.023 15.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3449 PF11931.8 KER27268.1 - 0.26 11.0 2.7 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) HCO3_cotransp PF00955.21 KER27271.1 - 2.9e-79 267.2 14.8 3.8e-78 263.5 14.8 2.0 1 1 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 KER27272.1 - 9.9e-26 91.1 11.6 3.5e-24 86.1 0.4 3.9 4 0 0 4 4 4 2 Band 3 cytoplasmic domain Sec62 PF03839.16 KER27275.1 - 6.2e-64 215.5 0.0 9.1e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 zf-C4 PF00105.18 KER27276.1 - 4.2e-27 94.4 14.5 8.1e-27 93.5 14.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER27276.1 - 6.1e-09 35.8 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Novirhabdo_Nv PF05554.11 KER27277.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Viral hemorrhagic septicemia virus non-virion protein Arfaptin PF06456.13 KER27278.1 - 5.6e-75 251.8 9.0 7.6e-75 251.4 9.0 1.2 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 KER27278.1 - 2.1e-13 51.2 13.9 9.4e-13 49.1 13.9 2.1 1 1 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain PDZ_6 PF17820.1 KER27279.1 - 2.1e-09 37.1 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER27279.1 - 4.3e-09 36.6 0.0 7.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER27279.1 - 8.5e-05 22.8 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 KER27279.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF2742 PF10888.8 KER27281.1 - 4.6e-05 23.6 0.1 1.5 9.2 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2742) CNF1 PF05785.12 KER27281.1 - 0.12 11.7 0.0 5.6 6.1 0.0 2.8 3 0 0 3 3 3 0 Rho-activating domain of cytotoxic necrotizing factor NUC153 PF08159.12 KER27281.1 - 0.18 11.7 6.7 10 6.0 0.1 3.4 3 0 0 3 3 3 0 NUC153 domain TubC_N PF18563.1 KER27281.1 - 0.27 11.2 1.3 8.3 6.5 0.0 3.1 3 0 0 3 3 3 0 TubC N-terminal docking domain zf-RING_6 PF14835.6 KER27281.1 - 0.4 10.6 3.9 39 4.2 0.1 3.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein SASRP1 PF15160.6 KER27282.1 - 0.11 12.2 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 U3snoRNP10 PF12397.8 KER27287.1 - 0.00098 19.5 0.1 0.00098 19.5 0.1 3.3 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 KER27287.1 - 0.01 16.3 1.3 0.094 13.2 0.1 3.6 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 KER27287.1 - 0.08 13.3 0.4 0.88 10.0 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats AIM5 PF17050.5 KER27287.1 - 0.79 10.6 2.6 2 9.3 0.5 2.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 TTL PF03133.15 KER27288.1 - 1.1e-28 100.2 0.5 1.5e-24 86.6 0.2 2.5 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family TPR_19 PF14559.6 KER27289.1 - 8.8e-06 26.1 4.4 0.34 11.5 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER27289.1 - 0.047 14.0 0.8 12 6.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KER27289.1 - 0.09 13.2 6.7 16 6.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KER27289.1 - 0.51 11.0 2.4 25 5.6 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER27289.1 - 4.9 7.5 8.1 1.5 9.1 0.2 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER27289.1 - 8.3 7.5 7.7 8.6 7.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat OrfB_Zn_ribbon PF07282.11 KER27290.1 - 0.16 11.9 8.1 0.19 11.7 4.0 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2HE PF16278.5 KER27292.1 - 0.028 14.9 0.1 16 6.1 0.0 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L6 PF00347.23 KER27296.1 - 5.4e-28 97.5 4.9 3.6e-16 59.6 0.7 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L27e PF01777.18 KER27298.1 - 9.4e-31 106.0 5.2 1.3e-30 105.6 5.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KER27298.1 - 7.3e-05 22.6 1.1 0.00016 21.5 1.1 1.7 1 1 0 1 1 1 1 KOW motif RNA_pol_Rpb2_4 PF04566.13 KER27298.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 ATP-synt_ab PF00006.25 KER27299.1 - 1.2e-74 250.6 0.0 1.7e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KER27299.1 - 7.8e-48 162.0 2.4 1.5e-47 161.0 2.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KER27299.1 - 8.9e-18 64.6 1.4 2.5e-17 63.2 1.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 KER27299.1 - 0.011 16.0 0.9 0.021 15.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) HAS-barrel PF09378.10 KER27299.1 - 0.014 15.6 0.7 0.05 13.8 0.7 2.0 1 1 0 1 1 1 0 HAS barrel domain ATPase PF06745.13 KER27299.1 - 0.038 13.3 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC RVT_1 PF00078.27 KER27301.1 - 2.8e-38 131.7 0.0 4.5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1751 PF08551.10 KER27301.1 - 1.3e-06 28.9 0.6 3.5e-06 27.5 0.6 1.8 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Sel1 PF08238.12 KER27302.1 - 2.2e-16 59.9 28.6 7.7e-06 26.4 1.1 5.9 7 0 0 7 7 7 4 Sel1 repeat Ubiq_cyt_C_chap PF03981.12 KER27302.1 - 0.012 15.8 0.5 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone Styelin PF17562.2 KER27302.1 - 0.043 14.2 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Styelin ANAPC3 PF12895.7 KER27302.1 - 0.45 10.8 5.0 0.54 10.5 1.2 2.9 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KER27302.1 - 8.4 7.3 10.3 5.5 7.8 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Mre11_DNA_bind PF04152.14 KER27303.1 - 1.5e-29 103.5 0.0 2.8e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KER27303.1 - 3.9e-14 53.6 2.4 6.2e-14 53.0 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KER27303.1 - 4.6e-05 23.7 0.0 0.00041 20.6 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EDR1 PF14381.6 KER27304.1 - 1e-38 133.1 0.1 3.2e-38 131.5 0.0 1.9 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 Arm PF00514.23 KER27304.1 - 3.8e-19 68.0 18.4 7.4e-05 22.7 0.0 9.0 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KER27304.1 - 2.1e-14 53.6 7.8 0.056 13.8 0.3 6.3 4 3 3 7 7 7 5 HEAT repeats HEAT PF02985.22 KER27304.1 - 1.2e-08 34.4 13.0 0.1 12.9 0.1 8.0 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KER27304.1 - 0.00032 21.1 14.0 5.4 7.6 0.1 6.9 6 1 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 KER27304.1 - 0.00034 20.7 6.6 0.84 9.7 0.8 4.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KER27304.1 - 0.00072 19.7 0.6 0.63 10.2 0.1 4.1 3 0 0 3 3 3 1 V-ATPase subunit H RICTOR_V PF14668.6 KER27304.1 - 0.0066 16.7 3.9 21 5.5 0.1 5.0 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF2937 PF11157.8 KER27304.1 - 0.0087 15.8 0.1 0.034 13.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) RTP1_C1 PF10363.9 KER27304.1 - 0.061 13.5 1.7 49 4.1 0.0 4.2 3 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 KER27304.1 - 0.12 11.4 10.4 0.58 9.2 0.1 3.9 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal IFRD PF05004.13 KER27304.1 - 3.2 6.8 8.1 2.5 7.1 0.1 3.7 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) RasGEF_N_2 PF14663.6 KER27304.1 - 4.7 7.7 8.9 31 5.0 0.1 5.2 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DnaJ PF00226.31 KER27305.1 - 1.7e-17 63.3 1.1 3.8e-17 62.2 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 KER27305.1 - 3.1e-08 34.5 0.3 1.3e-07 32.5 0.3 2.2 1 0 0 1 1 1 1 Ribosome-associated complex head domain Myb_DNA-binding PF00249.31 KER27305.1 - 5.4e-08 32.9 0.2 5e-06 26.6 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KER27305.1 - 0.0017 18.6 0.1 0.12 12.7 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Bax1-I PF01027.20 KER27306.1 - 1.7e-19 70.5 31.1 3.1e-16 59.8 21.8 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 PetM PF08041.11 KER27306.1 - 0.54 9.9 4.6 1.3 8.6 4.6 1.7 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Bax1-I PF01027.20 KER27307.1 - 3.4e-29 102.2 29.3 4.7e-29 101.7 29.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Exo_endo_phos PF03372.23 KER27307.1 - 0.0053 16.3 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATP_synth_reg PF14960.6 KER27307.1 - 0.025 14.1 0.4 0.067 12.7 0.4 1.7 1 0 0 1 1 1 0 ATP synthase regulation RRM_5 PF13893.6 KER27308.1 - 5.6e-41 139.1 5.8 6.1e-29 100.2 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER27308.1 - 2.8e-26 91.1 0.1 9.8e-09 34.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER27308.1 - 6.5e-11 41.9 0.2 0.41 10.5 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_8 PF11835.8 KER27308.1 - 2.9e-05 24.2 0.3 8.7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 RRM-like domain HMw1_D2 PF18254.1 KER27308.1 - 0.13 12.7 0.1 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 HMW1 domain 2 DUF4407 PF14362.6 KER27309.1 - 0.0056 16.1 10.9 0.0056 16.1 10.9 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4407) DUF812 PF05667.11 KER27309.1 - 0.0063 15.5 1.3 0.0063 15.5 1.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF812) Rab5-bind PF09311.11 KER27309.1 - 0.071 12.5 30.7 0.01 15.3 16.8 3.6 3 1 0 3 3 3 0 Rabaptin-like protein CdvA PF18822.1 KER27309.1 - 0.073 12.9 0.2 0.073 12.9 0.2 4.5 4 1 0 4 4 4 0 CdvA-like coiled-coil domain ERM PF00769.19 KER27309.1 - 0.41 10.4 29.1 0.9 9.3 0.8 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Gsf2 PF11055.8 KER27309.1 - 0.44 9.2 1.6 0.71 8.6 0.1 1.9 2 0 0 2 2 2 0 Glucose signalling factor 2 Golgin_A5 PF09787.9 KER27309.1 - 0.65 9.4 34.2 0.17 11.3 11.1 3.6 2 1 1 3 3 3 0 Golgin subfamily A member 5 ASL_C PF08328.11 KER27309.1 - 1.2 9.3 5.8 5.5 7.1 0.0 3.4 3 1 1 4 4 4 0 Adenylosuccinate lyase C-terminal HIP1_clath_bdg PF16515.5 KER27309.1 - 4 8.1 37.2 0.98 10.1 6.4 5.1 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MobL PF18555.1 KER27309.1 - 4.9 6.3 16.1 0.14 11.4 8.2 2.0 2 0 0 2 2 2 0 MobL relaxases DUF4709 PF15821.5 KER27309.1 - 6.8 7.0 16.6 0.76 10.1 2.7 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4709) Sec8_exocyst PF04048.14 KER27309.1 - 8.5 6.3 10.6 3.3 7.6 0.7 3.5 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 KER27309.1 - 8.7 6.4 36.6 2.1 8.4 0.9 4.5 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein zf-RING_2 PF13639.6 KER27310.1 - 3.4e-09 36.9 4.5 6e-09 36.1 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KER27310.1 - 1.5e-06 27.8 2.3 2.9e-06 26.9 2.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KER27310.1 - 3.3e-05 23.7 2.1 5.6e-05 23.0 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KER27310.1 - 5.5e-05 22.9 5.2 0.0001 22.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER27310.1 - 8.3e-05 22.8 5.1 0.00021 21.5 5.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KER27310.1 - 8.4e-05 22.4 3.7 0.00015 21.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KER27310.1 - 0.00022 20.8 2.2 0.00043 19.9 2.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KER27310.1 - 0.00073 19.4 2.1 0.0016 18.3 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER27310.1 - 0.00077 19.5 1.8 0.0014 18.6 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KER27310.1 - 0.0023 17.9 4.9 0.005 16.8 4.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_2 PF10367.9 KER27310.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.29 KER27310.1 - 0.21 11.5 2.9 0.41 10.6 2.9 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KER27310.1 - 1.4 8.9 4.3 3 7.8 4.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 KER27310.1 - 2 8.4 5.4 14 5.7 5.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KER27311.1 - 4.3e-12 46.2 6.4 4.3e-12 46.2 6.4 2.0 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 KER27311.1 - 2.8e-08 33.5 2.2 2.8e-08 33.5 2.2 2.2 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KER27311.1 - 1.8e-07 30.8 7.7 1.8e-07 30.8 7.7 2.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KER27311.1 - 2.4e-07 30.5 6.8 2.4e-07 30.5 6.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER27311.1 - 5.4e-05 23.4 11.2 8.6e-05 22.7 8.9 2.3 2 1 1 3 3 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER27311.1 - 0.00011 22.2 8.6 0.00016 21.6 6.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER27311.1 - 0.00012 22.0 5.1 0.00012 22.0 5.1 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KER27311.1 - 0.00034 20.6 5.7 0.00059 19.8 5.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1997 PF09366.10 KER27311.1 - 0.0024 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) zf-C3HC4_3 PF13920.6 KER27311.1 - 0.0037 17.1 9.9 0.017 15.0 10.2 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KER27311.1 - 0.0084 16.2 1.8 0.025 14.7 1.8 1.8 1 1 0 1 1 1 1 RING-variant domain Complex1_LYR_2 PF13233.6 KER27311.1 - 0.0089 16.8 1.0 0.044 14.5 0.3 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Zn_ribbon_17 PF17120.5 KER27311.1 - 0.024 14.3 9.2 0.04 13.5 9.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KER27311.1 - 0.17 11.7 13.5 0.055 13.3 5.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 KER27311.1 - 1.4 8.8 11.8 0.57 10.1 7.4 2.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.27 KER27314.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YbjM PF11045.8 KER27315.1 - 0.49 10.6 3.6 1.2 9.4 1.5 2.4 2 1 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae zf-RING_11 PF17123.5 KER27317.1 - 1.6e-10 40.5 4.7 3.8e-10 39.3 4.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KER27317.1 - 2.4e-10 40.6 2.0 6.8e-10 39.1 2.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KER27317.1 - 1.4e-07 31.4 0.3 3.8e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER27317.1 - 5.6e-07 29.3 1.2 1.7e-06 27.8 1.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER27317.1 - 1e-06 28.6 1.3 2.2e-06 27.5 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KER27317.1 - 3.7e-06 26.7 1.2 9.9e-06 25.3 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KER27317.1 - 0.00055 19.8 0.8 0.0013 18.6 0.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 KER27317.1 - 0.00089 19.5 3.2 0.0046 17.2 3.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KER27317.1 - 0.0017 17.9 1.0 0.0054 16.3 1.0 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type SpoIISA_toxin PF14171.6 KER27317.1 - 0.0026 17.5 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Toxin SpoIISA, type II toxin-antitoxin system Baculo_RING PF05883.11 KER27317.1 - 0.0034 17.4 0.1 0.0078 16.2 0.1 1.6 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain Zf_RING PF16744.5 KER27317.1 - 0.0077 16.3 0.8 0.024 14.7 0.8 1.9 1 0 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 KER27317.1 - 0.011 15.6 0.7 0.028 14.3 0.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HSBP1 PF06825.12 KER27317.1 - 0.028 14.3 0.4 2.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 zf-ANAPC11 PF12861.7 KER27317.1 - 0.05 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KER27317.1 - 0.056 13.6 0.6 0.15 12.2 0.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KER27317.1 - 0.14 12.0 1.6 0.33 10.9 1.1 1.9 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.7 KER27317.1 - 0.88 9.7 5.4 0.17 12.0 1.0 2.2 2 1 0 2 2 2 0 RING-variant domain Peptidase_C2 PF00648.21 KER27318.1 - 3.2e-105 351.4 0.0 4.6e-105 350.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KER27318.1 - 3.4e-37 127.8 0.0 5.8e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 KER27318.1 - 0.19 11.3 0.1 34 4.3 0.0 3.1 2 1 1 3 3 3 0 EF hand CAMSAP_CKK PF08683.11 KER27319.1 - 6.9e-35 119.8 0.0 1.5e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated HSCB_C PF07743.13 KER27319.1 - 4.7e-07 30.2 3.3 4.7e-07 30.2 3.3 2.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain Ketoacyl-synt_2 PF13723.6 KER27319.1 - 0.091 12.4 1.8 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain UPF0556 PF10572.9 KER27321.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0556 MMACHC PF16690.5 KER27322.1 - 1.5e-64 217.7 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family MFS_1 PF07690.16 KER27323.1 - 3e-05 23.1 4.0 3e-05 23.1 4.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily GIY-YIG PF01541.24 KER27323.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain MFS_1 PF07690.16 KER27324.1 - 2e-20 73.0 29.3 6.3e-18 64.8 17.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Exo_endo_phos_2 PF14529.6 KER27324.1 - 3.8e-08 33.2 0.1 6.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BaxI_1 PF12811.7 KER27324.1 - 0.0023 17.5 8.7 0.0037 16.9 8.7 1.3 1 0 0 1 1 1 1 Bax inhibitor 1 like ATP1G1_PLM_MAT8 PF02038.16 KER27324.1 - 0.084 12.3 0.4 23 4.5 0.1 3.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF2108 PF09881.9 KER27324.1 - 2.4 8.2 7.4 40 4.3 5.6 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2108) TauE PF01925.19 KER27324.1 - 10 5.7 29.5 2.3 7.8 6.7 3.1 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE Glyco_transf_7N PF13733.6 KER27327.1 - 6.3e-40 135.9 0.0 9.8e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KER27327.1 - 1.3e-24 85.6 0.0 2.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase MAP65_ASE1 PF03999.12 KER27328.1 - 1.5e-43 149.4 4.0 2.3e-43 148.8 4.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cas_Csn2 PF09711.10 KER27328.1 - 0.0032 17.1 2.1 0.013 15.2 0.1 2.8 3 1 1 4 4 4 1 CRISPR-associated protein (Cas_Csn2) BLOC1_2 PF10046.9 KER27328.1 - 1.4 9.2 4.8 3.8 7.9 0.0 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase_Tyr PF07714.17 KER27331.1 - 4.2e-94 314.6 0.0 6.4e-94 314.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER27331.1 - 4.3e-44 150.9 0.0 6.5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER27331.1 - 1.9e-20 72.7 0.1 4.6e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 KER27331.1 - 0.21 10.5 0.0 0.45 9.4 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Nop14 PF04147.12 KER27331.1 - 1.2 7.2 6.6 1.9 6.6 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 KER27331.1 - 1.5 8.5 4.6 4.6 6.9 4.6 1.8 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KER27331.1 - 5.9 6.1 12.3 10 5.3 12.3 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KER27331.1 - 6.9 4.8 5.6 11 4.2 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.27 KER27332.1 - 2.6e-11 43.4 0.0 4.9e-10 39.3 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF-1a PF01176.19 KER27332.1 - 1.3e-09 37.8 0.0 4.5e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 Pro_isomerase PF00160.21 KER27335.1 - 5e-38 130.9 0.0 1.2e-37 129.6 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1216 PF06746.11 KER27335.1 - 0.062 13.3 0.4 0.39 10.7 0.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) F_actin_bind PF08919.10 KER27335.1 - 1.7 8.8 4.5 1.6 8.8 0.1 3.2 3 0 0 3 3 3 0 F-actin binding Swi3 PF07962.12 KER27336.1 - 3.4e-22 78.2 0.0 8.8e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 IER PF05760.12 KER27337.1 - 0.057 13.7 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) Usp PF00582.26 KER27338.1 - 2.4e-26 93.0 0.0 3.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family TMEM101 PF15111.6 KER27339.1 - 3.3e-07 30.1 8.2 4e-05 23.3 1.9 2.1 2 0 0 2 2 2 2 TMEM101 protein family RE_TaqI PF09573.10 KER27341.1 - 0.0003 20.7 1.0 1 9.1 0.1 2.7 2 0 0 2 2 2 2 TaqI restriction endonuclease Asp_protease_2 PF13650.6 KER27341.1 - 0.017 15.7 0.0 7.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease PolyA_pol_arg_C PF12626.7 KER27344.1 - 0.16 12.0 0.5 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus PolyA_pol_RNAbd PF12627.7 KER27345.1 - 0.064 13.0 0.4 0.17 11.7 0.1 1.9 2 1 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A FadA PF09403.10 KER27346.1 - 0.14 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Adhesion protein FadA RRM_1 PF00076.22 KER27347.1 - 5e-20 71.1 0.0 1.9e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOCS_box PF07525.16 KER27348.1 - 0.0011 19.3 0.5 0.0031 17.8 0.5 1.8 1 0 0 1 1 1 1 SOCS box SOCS_box PF07525.16 KER27349.1 - 0.037 14.4 0.2 0.11 12.9 0.2 2.0 1 1 0 1 1 1 0 SOCS box RVT_1 PF00078.27 KER27350.1 - 9.1e-09 35.2 0.0 4.3e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSC22 PF01166.18 KER27350.1 - 0.38 11.1 4.0 15 6.0 0.5 3.4 2 0 0 2 2 2 0 TSC-22/dip/bun family HPPK PF01288.20 KER27350.1 - 0.43 11.1 1.9 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF4472 PF14739.6 KER27350.1 - 2.8 8.7 12.6 0.57 10.9 3.8 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Ank_3 PF13606.6 KER27351.1 - 2.9e-11 42.5 0.3 0.0023 18.3 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KER27351.1 - 5.9e-11 42.8 0.0 4.4e-08 33.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER27351.1 - 1.2e-06 28.9 0.1 0.00059 20.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER27351.1 - 3.5e-06 27.2 0.3 0.00024 21.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KER27351.1 - 0.00079 19.8 0.4 0.088 13.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat LRR_4 PF12799.7 KER27351.1 - 0.0083 16.5 13.0 8.3 7.0 0.0 6.4 4 3 3 7 7 7 3 Leucine Rich repeats (2 copies) TPR_12 PF13424.6 KER27351.1 - 0.064 13.6 1.6 11 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 KER27351.1 - 0.13 12.9 22.6 19 6.3 0.1 8.5 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 KER27351.1 - 0.15 12.2 14.4 3.8 7.8 0.2 7.3 9 0 0 9 9 9 0 Leucine Rich repeat TPR_12 PF13424.6 KER27352.1 - 9.9e-11 41.8 3.3 8e-05 22.9 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER27352.1 - 6.5e-07 29.0 3.4 0.098 12.8 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER27352.1 - 3.4e-05 23.7 1.5 0.48 10.8 0.1 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER27352.1 - 0.00029 20.3 0.2 0.092 12.1 0.0 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 KER27352.1 - 0.0003 20.5 1.3 0.82 9.6 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER27352.1 - 0.00038 20.3 2.0 1.1 9.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER27352.1 - 0.0017 18.9 0.1 7.4 7.4 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER27352.1 - 0.0018 18.8 4.7 0.029 14.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER27352.1 - 0.0048 17.5 0.1 0.41 11.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER27352.1 - 0.012 15.4 0.5 0.049 13.5 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.12 KER27352.1 - 0.023 14.7 2.5 0.39 10.8 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_14 PF13428.6 KER27352.1 - 0.03 15.1 0.9 2.8 9.0 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER27352.1 - 0.28 11.4 8.9 1.5 9.1 0.3 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NKAP PF15692.5 KER27353.1 - 0.0017 19.0 17.5 0.0054 17.4 0.1 3.3 3 0 0 3 3 3 2 NF-kappa-B-activating protein OMP_b-brl PF13505.6 KER27354.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain MelC1 PF06236.11 KER27356.1 - 0.035 14.2 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Cupin_1 PF00190.22 KER27356.1 - 0.082 12.5 0.2 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Cupin Cas_Cas4 PF01930.17 KER27357.1 - 0.021 14.9 0.0 0.021 14.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF83 EMP24_GP25L PF01105.24 KER27359.1 - 1.3e-08 35.0 1.7 2e-08 34.4 1.7 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EMP24_GP25L PF01105.24 KER27360.1 - 1.1e-19 71.1 0.0 1.4e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD hSac2 PF12456.8 KER27361.1 - 8.9e-15 54.4 0.1 1.5e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Inositol phosphatase RRM_1 PF00076.22 KER27361.1 - 7.6e-14 51.3 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER27361.1 - 0.00028 20.5 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER27361.1 - 0.0011 19.1 0.0 0.0066 16.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif Pkinase PF00069.25 KER27362.1 - 8.4e-60 202.4 0.0 1.5e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27362.1 - 1.9e-20 73.2 0.0 1.2e-19 70.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TFIID-18kDa PF02269.16 KER27362.1 - 3.3e-11 43.1 0.3 7.5e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit APH PF01636.23 KER27362.1 - 0.018 15.0 0.3 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KER27363.1 - 1.7e-67 227.6 0.0 2.2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27363.1 - 2e-37 128.9 0.0 2.7e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KER27363.1 - 1.5e-10 41.1 0.0 3.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 KER27363.1 - 1.4e-07 31.1 0.0 7.8e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KER27363.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER27363.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRP1_N PF06424.12 KER27364.1 - 3.1e-53 180.2 8.1 3.1e-53 180.2 8.1 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KER27364.1 - 6.1e-33 110.7 37.7 2.7e-05 24.6 0.4 14.5 5 5 10 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 KER27364.1 - 1.3e-20 73.6 19.1 8.9e-08 32.5 0.2 9.5 9 3 3 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KER27364.1 - 8.7e-11 41.4 0.1 1.2 9.7 0.0 8.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER27364.1 - 1.9e-06 28.4 21.9 0.0047 17.6 2.6 7.4 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KER27364.1 - 1.1e-05 25.2 0.1 2.1 8.7 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 KER27364.1 - 1.2e-05 25.5 3.6 1.1 9.2 0.0 5.1 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) FAT PF02259.23 KER27364.1 - 2e-05 24.0 19.6 2.7e-05 23.6 4.5 4.6 1 1 2 4 4 4 1 FAT domain TPR_2 PF07719.17 KER27364.1 - 0.00011 22.0 12.6 2.1 8.7 0.2 9.9 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER27364.1 - 0.0007 19.8 16.5 0.0029 17.9 1.7 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER27364.1 - 0.00073 19.7 2.5 0.75 10.1 0.5 5.4 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KER27364.1 - 0.0047 16.6 0.0 0.53 10.0 0.0 4.2 4 1 1 5 5 5 1 TPR repeat TPR_6 PF13174.6 KER27364.1 - 0.084 13.6 12.9 42 5.1 0.0 8.8 10 1 1 11 11 10 0 Tetratricopeptide repeat SNAP PF14938.6 KER27364.1 - 0.11 11.9 6.9 0.092 12.2 0.3 3.1 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.14 KER27364.1 - 0.12 13.1 6.8 6 7.8 0.2 5.2 4 1 0 4 4 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KER27364.1 - 0.44 10.4 10.8 3.9 7.3 0.2 4.1 4 1 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 KER27364.1 - 0.62 10.3 11.2 14 5.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KER27364.1 - 0.85 9.3 10.9 0.32 10.7 1.5 4.2 4 2 0 4 4 4 0 Tetratricopeptide repeat-like domain Ribosomal_L31e PF01198.19 KER27364.1 - 2 8.7 5.5 2 8.7 0.0 2.8 2 1 1 3 3 2 0 Ribosomal protein L31e RhoGAP PF00620.27 KER27366.1 - 2.1e-18 66.6 0.0 4.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Kinesin PF00225.23 KER27368.1 - 0.00042 19.4 0.2 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain CDH1_2_SANT_HL1 PF18375.1 KER27368.1 - 0.095 13.4 6.5 1.2 9.9 2.5 2.6 1 1 1 2 2 2 0 CDH1/2 SANT-Helical linker 1 GPS2_interact PF15784.5 KER27368.1 - 0.14 12.6 7.6 0.081 13.4 2.1 2.5 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF4164 PF13747.6 KER27368.1 - 0.36 11.1 15.6 0.22 11.8 5.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) LPP PF04728.13 KER27368.1 - 0.73 10.3 6.6 13 6.3 2.5 3.0 2 1 1 3 3 3 0 Lipoprotein leucine-zipper TMPIT PF07851.13 KER27368.1 - 3.1 7.0 6.3 1.5 8.0 3.0 1.9 2 0 0 2 2 2 0 TMPIT-like protein Inositol_P PF00459.25 KER27373.1 - 4.2e-34 118.3 4.2 1.7e-18 67.1 0.1 2.1 1 1 1 2 2 2 2 Inositol monophosphatase family DUF4744 PF15918.5 KER27374.1 - 0.22 12.4 0.9 7.1 7.6 0.9 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) MFS_1 PF07690.16 KER27375.1 - 2.5e-37 128.6 36.4 2.5e-37 128.6 36.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-H PF05837.12 KER27377.1 - 0.007 16.8 1.9 0.024 15.1 1.1 2.3 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Lys_export PF03956.13 KER27378.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Lysine exporter LysO RVT_1 PF00078.27 KER27378.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_fiber_2 PF03406.13 KER27380.1 - 0.029 13.9 0.2 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat Ins_P5_2-kin PF06090.12 KER27381.1 - 1.3e-58 199.1 0.0 1.5e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4497 PF14924.6 KER27382.1 - 3.9e-05 24.1 0.1 0.00023 21.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) UNC80 PF15778.5 KER27383.1 - 1.9e-13 50.5 0.0 3.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Cation channel complex component UNC80 Mitoc_L55 PF09776.9 KER27389.1 - 2e-07 30.8 0.1 7.9e-07 28.8 0.1 2.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 DUF4692 PF15763.5 KER27390.1 - 0.074 13.5 0.8 0.14 12.6 0.5 1.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Lyase_1 PF00206.20 KER27391.1 - 1.9e-25 89.9 0.0 3.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KER27391.1 - 1.1e-12 48.3 0.2 3.6e-12 46.6 0.2 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SafA PF17073.5 KER27391.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Two-component-system connector protein DUF3616 PF12275.8 KER27391.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) WD40 PF00400.32 KER27392.1 - 4.4e-36 122.3 24.0 2.2e-08 34.6 0.1 10.5 11 1 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 KER27392.1 - 1.1e-08 35.3 0.7 2.1e-08 34.4 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KER27392.1 - 4.5e-07 30.1 0.1 0.76 10.1 0.0 6.5 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER27392.1 - 0.0029 17.5 0.0 0.072 13.0 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KER27392.1 - 0.01 15.2 0.0 0.66 9.3 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain MFS_1 PF07690.16 KER27393.1 - 3.1e-38 131.6 36.0 4.8e-18 65.2 3.9 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily COX8 PF02285.15 KER27393.1 - 0.084 12.8 0.0 0.39 10.6 0.0 2.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII TssN PF17555.2 KER27393.1 - 0.2 11.0 1.5 0.45 9.8 1.5 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssN ParcG PF10274.9 KER27394.1 - 1.4e-23 84.0 0.1 9.6e-23 81.2 0.1 1.9 1 1 0 1 1 1 1 Parkin co-regulated protein Pkinase_Tyr PF07714.17 KER27396.1 - 4.4e-81 272.0 0.0 5e-39 134.1 0.0 3.3 1 1 2 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KER27396.1 - 1.8e-41 142.3 0.0 2.2e-25 89.5 0.0 3.2 1 1 2 3 3 3 2 Protein kinase domain Focal_AT PF03623.13 KER27396.1 - 9.2e-37 126.0 0.3 1.4e-36 125.4 0.3 1.3 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase_fungal PF17667.1 KER27396.1 - 0.017 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Abi_2 PF07751.11 KER27396.1 - 0.14 12.4 0.1 8.1 6.7 0.0 2.4 1 1 0 2 2 2 0 Abi-like protein Haspin_kinase PF12330.8 KER27396.1 - 0.16 10.9 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Galactosyl_T PF01762.21 KER27397.1 - 9.8e-54 182.1 0.0 2.7e-26 92.6 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase p12I PF12233.8 KER27397.1 - 0.0077 16.7 1.1 0.39 11.2 0.1 3.1 2 0 0 2 2 2 1 Human adult T cell leukemia/lymphoma virus protein Glyco_transf_8 PF01501.20 KER27398.1 - 5.9e-06 26.0 0.1 8.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 KER27399.1 - 0.0014 18.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 HPPK PF01288.20 KER27400.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) CDP-OH_P_transf PF01066.21 KER27401.1 - 1.6e-17 64.0 0.1 1.6e-17 64.0 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EGF_2 PF07974.13 KER27404.1 - 0.03 14.7 5.9 0.16 12.4 5.9 2.1 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.27 KER27404.1 - 0.037 14.3 3.7 0.52 10.7 3.7 2.4 1 1 0 1 1 1 0 EGF-like domain MtrF PF09472.10 KER27404.1 - 2.8 7.4 6.1 4.4 6.8 6.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Hormone_recep PF00104.30 KER27405.1 - 8.6e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KER27405.1 - 0.07 13.6 0.5 0.17 12.3 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) SCHIP-1 PF10148.9 KER27409.1 - 2.9e-14 53.2 1.1 2.9e-14 53.2 1.1 2.7 3 0 0 3 3 3 1 Schwannomin-interacting protein 1 FEZ PF07763.13 KER27409.1 - 0.0069 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 FEZ-like protein RVT_1 PF00078.27 KER27410.1 - 8.4e-07 28.7 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 KER27414.1 - 5.7e-14 52.2 8.6 4.7e-10 39.7 0.2 4.9 5 1 0 5 5 5 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER27414.1 - 0.00075 20.0 0.6 0.088 13.4 0.0 3.8 4 0 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KER27414.1 - 0.0049 17.2 0.0 2.8 8.4 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2369) Actin PF00022.19 KER27416.1 - 7.8e-146 485.8 0.0 2.5e-145 484.2 0.0 1.6 1 1 0 1 1 1 1 Actin DNA_pol_B PF00136.21 KER27418.1 - 4.8e-109 365.1 0.0 1.7e-107 360.0 0.0 2.5 2 1 1 3 3 3 1 DNA polymerase family B DNA_pol_alpha_N PF12254.8 KER27418.1 - 1.6e-29 101.8 13.7 4.7e-18 65.0 4.5 2.6 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 KER27418.1 - 1.5e-12 47.4 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 KER27418.1 - 0.0016 17.4 0.0 0.0032 16.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Orbi_VP2 PF00898.17 KER27418.1 - 0.12 10.1 1.7 5.4 4.6 0.7 2.1 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP2 RT_RNaseH PF17917.1 KER27422.1 - 7.3e-31 106.6 0.0 1.9e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER27422.1 - 4.1e-29 100.6 0.0 1e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KER27422.1 - 1.9e-24 86.1 0.0 4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KER27422.1 - 3.9e-08 33.1 0.0 8.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_PH PF01138.21 KER27422.1 - 3.8e-06 27.4 0.1 8.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Integrase_H2C2 PF17921.1 KER27422.1 - 6.7e-06 26.1 0.1 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER27422.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Claudin_2 PF13903.6 KER27423.1 - 0.0098 15.7 1.5 0.015 15.0 1.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction ASC PF00858.24 KER27424.1 - 1.3e-22 80.4 6.0 4.2e-20 72.2 6.0 2.2 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF5480 PF17576.2 KER27424.1 - 0.047 13.7 0.0 0.67 10.0 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5480) RhoGEF PF00621.20 KER27426.1 - 3.1e-25 89.5 0.0 6.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 KER27426.1 - 7.9e-11 41.7 1.7 3.8e-08 33.2 0.2 3.8 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 KER27426.1 - 1e-06 29.0 0.0 0.0049 17.2 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KER27426.1 - 0.012 16.0 0.0 7.9 7.0 0.0 3.2 3 1 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain TAF6_C PF07571.13 KER27428.1 - 1.8e-23 82.7 0.0 9e-23 80.4 0.0 2.1 1 1 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KER27428.1 - 5.7e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Kazal_2 PF07648.15 KER27429.1 - 3.1e-48 161.7 68.4 2.6e-09 37.1 3.9 8.4 7 0 0 7 7 7 6 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 KER27429.1 - 2.8e-30 104.1 72.0 2.8e-08 33.6 4.0 7.6 7 0 0 7 7 7 6 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.24 KER27429.1 - 3.7e-22 79.3 0.0 8.2e-08 32.9 0.0 4.6 4 0 0 4 4 4 3 Laminin G domain Laminin_G_1 PF00054.23 KER27429.1 - 5.4e-17 62.2 0.0 0.0056 16.9 0.1 5.2 4 1 0 4 4 4 3 Laminin G domain Laminin_EGF PF00053.24 KER27429.1 - 1.2e-13 50.9 36.5 2.9e-08 33.7 14.7 8.4 8 3 0 8 8 8 3 Laminin EGF domain EGF PF00008.27 KER27429.1 - 0.0001 22.5 8.2 0.0001 22.5 8.2 10.3 10 0 0 10 10 10 1 EGF-like domain hEGF PF12661.7 KER27429.1 - 0.00012 22.6 6.7 0.00012 22.6 6.7 9.1 8 0 0 8 8 8 1 Human growth factor-like EGF COX17 PF05051.13 KER27431.1 - 0.089 13.2 3.9 3.2 8.2 3.9 2.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Ion_trans PF00520.31 KER27432.1 - 0.17 11.1 16.2 0.067 12.4 4.6 3.2 2 1 1 3 3 3 0 Ion transport protein Amino_oxidase PF01593.24 KER27433.1 - 0.067 12.5 0.1 0.079 12.2 0.1 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase RGS PF00615.19 KER27438.1 - 1.8e-33 115.3 2.3 2.6e-33 114.8 2.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF349 PF03993.12 KER27438.1 - 8.9 6.7 7.2 2.4 8.5 2.5 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Unpaired PF15972.5 KER27439.1 - 0.028 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Unpaired protein Yop-YscD_ppl PF16693.5 KER27439.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain PHD20L1_u1 PF16660.5 KER27440.1 - 0.052 14.3 0.1 12 6.7 0.0 2.0 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 Ion_trans_2 PF07885.16 KER27442.1 - 5.2e-34 116.1 18.1 1.1e-17 63.8 1.0 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KER27442.1 - 1.1e-05 24.9 6.6 0.017 14.3 0.1 2.2 1 1 1 2 2 2 2 Ion transport protein Gmx_para_CXXCG PF09535.10 KER27444.1 - 0.037 13.3 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) RVT_1 PF00078.27 KER27445.1 - 3.3e-30 105.3 0.0 4.7e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KER27446.1 - 9e-21 73.8 1.2 0.00022 22.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER27446.1 - 1.5e-15 57.3 0.0 0.00015 22.0 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GMP_PDE_delta PF05351.11 KER27448.1 - 3.3e-10 40.2 0.0 5.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit SRP-alpha_N PF04086.13 KER27449.1 - 0.096 12.6 2.4 0.16 11.9 2.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ion_trans_2 PF07885.16 KER27451.1 - 5.1e-25 87.3 20.9 2e-14 53.3 0.8 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KER27451.1 - 1.7e-06 27.4 2.2 0.011 15.0 0.1 2.6 2 2 0 2 2 2 2 Ion transport protein Nab2 PF11517.8 KER27457.1 - 0.0081 16.4 0.9 29 5.0 0.0 4.3 4 0 0 4 4 4 2 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) CODH_A_N PF18537.1 KER27457.1 - 0.072 13.1 0.4 1.5e+02 2.5 0.0 4.1 4 0 0 4 4 4 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Ig_3 PF13927.6 KER27459.1 - 4.6e-39 132.9 0.0 7.9e-09 36.0 0.1 6.8 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KER27459.1 - 1.7e-26 92.1 0.0 1.5e-08 34.6 0.0 7.9 6 3 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KER27459.1 - 3.2e-22 78.6 0.0 0.0023 18.2 0.0 7.0 7 0 0 7 7 7 6 Immunoglobulin domain V-set PF07686.17 KER27459.1 - 4.5e-16 59.0 1.0 0.13 12.4 0.0 9.2 7 5 2 9 9 9 5 Immunoglobulin V-set domain ig PF00047.25 KER27459.1 - 2.4e-14 53.3 0.4 0.031 14.4 0.0 7.5 8 2 0 8 8 8 2 Immunoglobulin domain Ldl_recept_a PF00057.18 KER27459.1 - 6e-08 32.8 31.2 4.4e-07 30.0 8.7 3.3 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A Ig_6 PF18452.1 KER27459.1 - 0.00059 19.4 3.9 17 5.0 0.0 5.3 7 0 0 7 7 7 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER27459.1 - 0.0016 18.5 0.0 49 4.1 0.0 4.7 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain PKD_3 PF16820.5 KER27459.1 - 0.15 11.8 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 PKD-like domain Ig_2 PF13895.6 KER27460.1 - 7.5e-07 29.4 0.0 2.1e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KER27460.1 - 1.4e-05 25.6 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER27460.1 - 0.016 15.4 0.0 2.5 8.3 0.0 2.3 1 1 1 2 2 2 0 Immunoglobulin V-set domain ig PF00047.25 KER27460.1 - 0.023 14.8 0.0 0.18 12.0 0.0 2.3 2 1 0 2 2 2 0 Immunoglobulin domain LIM PF00412.22 KER27461.1 - 2.8e-54 181.2 51.8 8.1e-13 48.4 0.7 5.1 5 0 0 5 5 5 5 LIM domain Baculo_IE-1 PF05290.11 KER27461.1 - 1.1 9.2 15.5 3.2 7.7 0.7 2.6 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Aldedh PF00171.22 KER27462.1 - 6.7e-142 473.2 0.0 7.6e-142 473.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KER27462.1 - 0.046 12.8 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRF PF01765.19 KER27462.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosome recycling factor zf-H2C2_2 PF13465.6 KER27463.1 - 2.3e-10 40.4 60.5 1.3e-06 28.6 5.4 8.5 9 0 0 9 9 9 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KER27463.1 - 2.4e-07 30.4 65.4 8.3e-05 22.3 1.0 6.4 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KER27463.1 - 6.2e-06 26.4 77.0 0.00073 19.9 3.9 8.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER27463.1 - 2.7 9.1 70.1 0.077 13.9 3.3 8.6 8 0 0 8 8 8 0 C2H2-type zinc finger FXa_inhibition PF14670.6 KER27464.1 - 1.8e-42 143.3 128.1 1.3e-10 41.4 6.3 22.8 12 3 5 17 17 17 9 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KER27464.1 - 4.3e-28 96.9 43.7 6.5e-11 42.0 1.7 23.9 23 2 1 24 24 24 9 Complement Clr-like EGF-like EGF_CA PF07645.15 KER27464.1 - 2.1e-16 59.8 53.9 5.5e-09 36.1 4.5 21.1 15 3 5 20 20 20 6 Calcium-binding EGF domain Laminin_EGF PF00053.24 KER27464.1 - 1.7e-06 28.0 55.8 0.0002 21.4 17.3 20.1 6 5 13 19 19 19 9 Laminin EGF domain EGF PF00008.27 KER27464.1 - 0.0016 18.7 9.0 0.0016 18.7 9.0 25.5 25 0 0 25 25 25 13 EGF-like domain DSL PF01414.19 KER27464.1 - 0.002 18.4 8.9 0.002 18.4 8.9 17.8 16 3 2 18 18 18 4 Delta serrate ligand EGF_2 PF07974.13 KER27464.1 - 0.0099 16.2 12.5 0.0099 16.2 12.5 29.2 24 7 4 28 28 28 7 EGF-like domain Innexin PF00876.18 KER27466.1 - 8.3e-109 364.1 13.0 9.6e-109 363.9 13.0 1.0 1 0 0 1 1 1 1 Innexin SPC25 PF06703.11 KER27468.1 - 9.8e-46 155.5 0.1 1.1e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Claudin_2 PF13903.6 KER27468.1 - 0.029 14.1 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.15 KER27468.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase Ank_2 PF12796.7 KER27470.1 - 1.3e-17 64.1 0.5 8.3e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER27470.1 - 1.4e-17 63.5 1.7 6e-06 26.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER27470.1 - 5.8e-14 52.3 0.7 1.2e-05 25.7 0.1 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KER27470.1 - 1.6e-11 44.1 0.6 0.00047 20.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KER27470.1 - 1.3e-09 37.5 0.7 0.0013 19.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat EF-hand_9 PF14658.6 KER27470.1 - 0.0024 18.2 0.3 4.2 7.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain DUF429 PF04250.13 KER27470.1 - 0.097 12.4 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF429) TPR_1 PF00515.28 KER27472.1 - 1.9e-06 27.5 6.3 0.0054 16.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER27472.1 - 6.9e-06 25.8 8.2 0.014 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER27472.1 - 0.064 13.7 2.7 0.77 10.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER27472.1 - 0.23 11.6 0.9 0.76 10.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER27472.1 - 0.43 10.9 5.2 1 9.7 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER27472.1 - 0.45 10.9 4.4 3.1 8.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER27472.1 - 1.8 9.4 5.2 11 6.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PIH1 PF08190.12 KER27473.1 - 2.8e-33 114.7 1.9 3.9e-20 72.0 0.2 3.1 3 0 0 3 3 3 2 PIH1 N-terminal domain PIH1_CS PF18201.1 KER27473.1 - 1.4e-18 67.1 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain ig PF00047.25 KER27474.1 - 0.0012 19.0 0.1 0.97 9.6 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 KER27474.1 - 0.0092 16.6 0.6 6.9 7.3 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KER27474.1 - 0.013 15.7 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain Ig_6 PF18452.1 KER27474.1 - 0.061 12.9 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 KER27474.1 - 0.11 12.6 0.1 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_Tie2_1 PF10430.9 KER27474.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Profilin PF00235.19 KER27475.1 - 1.7e-06 28.3 0.0 1.8e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Profilin rve PF00665.26 KER27476.1 - 2.3e-17 63.3 0.0 4.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KER27476.1 - 6e-09 35.8 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CDGSH PF09360.10 KER27477.1 - 8e-14 51.6 14.4 3.6e-09 36.7 0.1 3.6 4 0 0 4 4 4 2 Iron-binding zinc finger CDGSH type GDNF PF02351.16 KER27477.1 - 0.057 14.4 5.9 11 7.1 0.0 2.7 2 1 0 2 2 2 0 GDNF/GAS1 domain SUI1 PF01253.22 KER27478.1 - 0.12 12.9 0.4 0.19 12.3 0.4 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 SUI1 PF01253.22 KER27479.1 - 9.7e-11 42.1 0.1 1.8e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dpy-30 PF05186.13 KER27480.1 - 1.7e-16 59.6 0.1 4.4e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 KER27480.1 - 1.3e-09 38.4 2.2 0.0027 17.8 0.0 3.9 5 0 0 5 5 4 2 Adenylate kinase AAA_17 PF13207.6 KER27480.1 - 3.3e-06 27.6 5.0 0.0022 18.4 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KER27480.1 - 0.00023 21.7 2.5 0.0026 18.3 0.0 3.9 5 1 0 5 5 4 1 AAA domain AAA_28 PF13521.6 KER27480.1 - 0.00062 20.0 4.7 0.0098 16.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Epimerase PF01370.21 KER27480.1 - 0.0011 18.5 0.3 0.0074 15.8 0.0 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family AAA_22 PF13401.6 KER27480.1 - 0.0012 19.1 0.5 0.48 10.7 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 KER27480.1 - 0.0014 19.1 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 KER27480.1 - 0.0022 18.3 0.0 0.0022 18.3 0.0 2.5 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain dNK PF01712.19 KER27480.1 - 0.0033 17.3 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.6 KER27480.1 - 0.0093 16.4 0.9 0.042 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KER27480.1 - 0.0094 16.1 1.5 0.013 15.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KER27480.1 - 0.019 14.9 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 0 NTPase GDP_Man_Dehyd PF16363.5 KER27480.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAA_24 PF13479.6 KER27480.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KER27480.1 - 0.12 12.5 0.0 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KER27480.1 - 0.12 12.7 0.1 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KER27480.1 - 0.15 12.6 0.2 0.95 10.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Endonuc_Holl PF10107.9 KER27480.1 - 0.16 11.8 5.1 0.5 10.2 5.1 1.8 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2012 PF09430.10 KER27481.1 - 1.1e-21 77.2 0.0 1.9e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) gag-asp_proteas PF13975.6 KER27481.1 - 2.8e-07 31.0 0.0 5.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER27481.1 - 4.8e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER27481.1 - 0.00076 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Gin PF10764.9 KER27481.1 - 0.2 11.7 2.1 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DSBA PF01323.20 KER27482.1 - 4.7e-35 121.1 0.0 3e-33 115.2 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain LAMTOR5 PF16672.5 KER27484.1 - 1.3e-10 41.0 0.0 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 RVT_1 PF00078.27 KER27485.1 - 1.3e-17 64.1 0.1 3.4e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_E8 PF03394.13 KER27488.1 - 0.058 12.9 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus E8 protein PCMT PF01135.19 KER27488.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SET PF00856.28 KER27489.1 - 1.3e-21 77.8 0.0 3.7e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 KER27489.1 - 1.1e-14 55.0 4.8 1.1e-14 55.0 4.8 1.8 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KER27489.1 - 2.4e-10 40.1 0.1 4.3e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Saccharop_dh_N PF04455.12 KER27489.1 - 0.081 13.3 0.0 27 5.2 0.0 2.5 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region DUF4660 PF15559.6 KER27490.1 - 0.027 14.8 0.1 0.04 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Kunitz_BPTI PF00014.23 KER27490.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Occludin_ELL PF07303.13 KER27494.1 - 4.8e-14 52.9 0.8 3.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Occludin homology domain ELL PF10390.9 KER27494.1 - 1.2e-10 41.4 0.0 6.4e-07 29.1 0.1 3.3 3 0 0 3 3 3 3 RNA polymerase II elongation factor ELL HTH_Tnp_1 PF01527.20 KER27494.1 - 0.00055 20.2 0.2 0.0015 18.8 0.2 1.7 1 0 0 1 1 1 1 Transposase LAP2alpha PF11560.8 KER27501.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha CKS PF01111.19 KER27504.1 - 1.9e-35 121.0 4.0 2.3e-35 120.7 4.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 KER27504.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Ldh_1_C PF02866.18 KER27506.1 - 3.7e-52 176.6 0.0 4.7e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KER27506.1 - 9.5e-14 51.7 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain TRP_N PF14558.6 KER27507.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 ML-like domain Phospholip_A2_2 PF05826.12 KER27508.1 - 3.8e-07 30.2 0.0 0.00035 20.8 0.1 2.4 2 0 0 2 2 2 2 Phospholipase A2 Phospholip_A2_2 PF05826.12 KER27509.1 - 1e-25 89.8 2.4 8.2e-25 86.9 2.2 2.1 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KER27509.1 - 0.053 14.0 9.3 5.4 7.5 9.3 2.3 1 1 0 1 1 1 0 Phospholipase A2 MFS_1 PF07690.16 KER27510.1 - 2.3e-15 56.4 20.0 2.4e-08 33.3 8.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 KER27510.1 - 0.16 11.7 3.3 0.47 10.3 0.5 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phospholip_A2_2 PF05826.12 KER27512.1 - 8.1e-22 77.3 2.1 1.5e-21 76.4 2.1 1.4 1 0 0 1 1 1 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 KER27512.1 - 0.048 14.1 5.6 0.13 12.7 5.6 1.8 1 1 0 1 1 1 0 Phospholipase A2 MFS_1 PF07690.16 KER27513.1 - 6.8e-24 84.4 33.5 1.9e-20 73.1 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0060 PF02694.15 KER27513.1 - 1.6 9.0 14.7 0.07 13.4 4.6 2.7 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family PH PF00169.29 KER27515.1 - 2e-05 25.1 0.0 3.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 KER27515.1 - 0.0017 18.4 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 PH domain FYVE PF01363.21 KER27515.1 - 0.013 15.6 0.2 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger PH_13 PF16652.5 KER27515.1 - 0.015 15.1 1.0 1.2 9.0 1.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain DEAD PF00270.29 KER27517.1 - 3.9e-46 157.0 0.9 7.4e-46 156.1 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER27517.1 - 3.3e-28 98.3 2.4 8.1e-25 87.3 0.2 3.7 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KER27517.1 - 5.8e-07 29.7 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KER27517.1 - 4.3e-06 27.1 0.2 9.3e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KER27517.1 - 9.9e-05 22.1 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER27517.1 - 0.0013 19.0 0.3 0.007 16.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain Fanconi_A PF03511.14 KER27517.1 - 0.0038 17.1 2.2 1.3 9.0 0.1 2.9 1 1 1 2 2 2 2 Fanconi anaemia group A protein Helicase_RecD PF05127.14 KER27517.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 KER27517.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KER27517.1 - 0.031 14.2 0.2 0.16 11.9 0.2 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain Gal-bind_lectin PF00337.22 KER27517.1 - 0.15 11.6 0.3 7.2 6.1 0.1 2.4 1 1 1 2 2 2 0 Galactoside-binding lectin ANAPC5 PF12862.7 KER27518.1 - 7.5e-05 22.7 0.5 7.5e-05 22.7 0.5 2.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 Exo_endo_phos_2 PF14529.6 KER27518.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase PHD_4 PF16866.5 KER27519.1 - 0.055 13.6 0.3 0.1 12.7 0.1 1.7 2 1 0 2 2 2 0 PHD-finger ATP-grasp_2 PF08442.10 KER27522.1 - 4.2e-68 228.9 0.9 6.2e-68 228.3 0.9 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KER27522.1 - 1.7e-21 76.7 0.8 2.5e-21 76.1 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KER27522.1 - 0.00058 19.4 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KER27522.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GARS_A PF01071.19 KER27522.1 - 0.0029 17.4 0.1 0.0088 15.8 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Q_salvage PF10343.9 KER27525.1 - 9.6e-35 120.5 0.0 1.9e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family rve PF00665.26 KER27525.1 - 4.3e-22 78.5 0.0 1.5e-21 76.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.22 KER27525.1 - 8.5e-16 57.5 0.2 1.1e-06 28.4 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 KER27525.1 - 9.9e-15 54.3 14.2 2.2e-14 53.2 14.2 1.6 1 0 0 1 1 1 1 OCRE domain rve_3 PF13683.6 KER27525.1 - 8.6e-06 25.4 0.0 4.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain SART-1 PF03343.13 KER27525.1 - 0.00042 19.0 0.1 0.00042 19.0 0.1 2.1 2 0 0 2 2 2 1 SART-1 family zf-RanBP PF00641.18 KER27525.1 - 0.00054 19.2 2.9 0.0013 18.0 2.9 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_jaz PF12171.8 KER27525.1 - 0.026 14.8 0.0 0.026 14.8 0.0 2.3 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding BRAP2 PF07576.12 KER27525.1 - 0.066 13.4 0.4 5.8 7.2 0.1 2.9 3 0 0 3 3 3 0 BRCA1-associated protein 2 Integrase_H2C2 PF17921.1 KER27525.1 - 1.3 9.2 6.5 0.16 12.1 1.1 2.3 2 0 0 2 2 2 0 Integrase zinc binding domain RED_N PF07808.13 KER27525.1 - 4.7 6.7 9.1 0.091 12.3 1.5 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region SET PF00856.28 KER27528.1 - 1.4e-19 71.1 0.3 4.4e-19 69.5 0.1 2.1 2 0 0 2 2 2 1 SET domain AWS PF17907.1 KER27528.1 - 1e-13 51.0 3.5 6e-13 48.6 3.5 2.4 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 KER27528.1 - 6.3e-10 38.8 58.9 2.6e-05 24.0 11.1 7.6 7 1 1 8 8 8 4 PHD-finger C5HCH PF17982.1 KER27528.1 - 6.6e-08 32.6 8.2 6.6e-08 32.6 8.2 4.1 4 0 0 4 4 4 1 NSD Cys-His rich domain zf-HC5HC2H PF13771.6 KER27528.1 - 0.022 15.0 0.1 0.022 15.0 0.1 5.9 5 1 1 6 6 6 0 PHD-like zinc-binding domain PWWP PF00855.17 KER27528.1 - 0.03 14.7 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 PWWP domain PHD_4 PF16866.5 KER27528.1 - 3 8.0 26.8 0.15 12.1 0.8 6.0 5 1 1 6 6 6 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KER27528.1 - 7.4 6.8 30.1 2.1 8.6 0.5 5.4 5 1 0 5 5 5 0 PHD-zinc-finger like domain DSS1_SEM1 PF05160.13 KER27529.1 - 1.3e-18 66.8 9.0 1.7e-18 66.4 9.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family CLASP_N PF12348.8 KER27531.1 - 1.1e-35 123.2 11.6 2.3e-09 37.2 0.0 8.3 7 2 1 8 8 8 6 CLASP N terminal HEAT_2 PF13646.6 KER27531.1 - 1e-10 41.8 19.5 0.05 14.0 0.0 12.0 9 3 2 11 11 11 2 HEAT repeats Cnd1 PF12717.7 KER27531.1 - 2.2e-09 37.5 13.6 0.016 15.3 0.1 8.9 10 3 1 11 11 11 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KER27531.1 - 1.3e-08 34.3 13.5 3.2 8.2 0.1 10.6 12 0 0 12 12 11 2 HEAT repeat TAN PF11640.8 KER27531.1 - 9.5e-07 29.1 9.3 0.13 12.4 0.0 6.3 5 1 0 5 5 5 2 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 KER27531.1 - 3.3e-06 26.0 20.4 0.03 12.9 0.1 7.6 8 1 1 9 9 9 3 Adaptin N terminal region NUC173 PF08161.12 KER27531.1 - 8e-05 22.4 0.2 14 5.3 0.0 6.3 6 1 0 6 6 6 0 NUC173 domain MMS19_N PF14500.6 KER27531.1 - 0.014 15.0 13.3 16 5.0 0.0 7.6 8 0 0 8 8 8 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KER27531.1 - 0.019 15.5 11.2 80 3.9 0.1 8.8 11 0 0 11 11 10 0 HEAT-like repeat IFRD PF05004.13 KER27531.1 - 0.072 12.2 2.6 13 4.8 0.0 4.6 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 KER27531.1 - 0.1 12.3 3.4 0.26 11.0 1.5 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis DCB PF16213.5 KER27531.1 - 0.16 11.6 7.1 0.16 11.6 0.1 3.9 5 0 0 5 5 5 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF4404 PF14357.6 KER27531.1 - 1.1 9.9 0.0 1.1 9.9 0.0 4.4 4 0 0 4 4 2 0 Domain of unknown function (DUF4404) SipA_VBS PF17985.1 KER27531.1 - 9.5 6.3 8.0 40 4.4 1.0 3.0 2 0 0 2 2 2 0 SipA vinculin binding site DUF4490 PF14892.6 KER27532.1 - 9.5e-05 22.4 0.0 9.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CDP-OH_P_transf PF01066.21 KER27533.1 - 1.1e-17 64.6 0.4 1.1e-17 64.6 0.4 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ThrE_2 PF12821.7 KER27534.1 - 0.18 11.9 0.9 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE HepII_C PF18675.1 KER27536.1 - 0.18 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Heparinase II C-terminal domain Mon1 PF03164.14 KER27537.1 - 2.7e-51 174.9 0.0 4e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Exo_endo_phos_2 PF14529.6 KER27537.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4930 PF16284.5 KER27540.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4930) zf-CCHC PF00098.23 KER27541.1 - 0.025 14.7 0.3 0.069 13.3 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle 7tm_1 PF00001.21 KER27542.1 - 4.3e-18 65.6 4.9 7e-18 64.9 0.1 2.3 3 0 0 3 3 3 2 7 transmembrane receptor (rhodopsin family) Fumerase_C PF05683.12 KER27543.1 - 7.4e-87 290.0 0.0 1.2e-86 289.3 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 KER27543.1 - 9.9e-85 284.2 0.0 1.3e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Colipase_C PF02740.14 KER27543.1 - 0.088 13.0 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Colipase, C-terminal domain NAD_kinase PF01513.21 KER27544.1 - 1.4e-53 182.0 0.0 4.1e-47 160.8 0.0 2.1 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 KER27544.1 - 1.4e-06 27.9 0.0 0.04 13.5 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain TPP_enzyme_C PF02775.21 KER27544.1 - 0.0099 15.7 0.1 3.9 7.3 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain WW PF00397.26 KER27545.1 - 4.2e-05 23.5 0.8 0.00016 21.7 0.3 2.4 2 0 0 2 2 2 1 WW domain Piwi PF02171.17 KER27546.1 - 8.7e-86 287.9 0.0 1.5e-85 287.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 KER27546.1 - 1.8e-10 40.8 0.1 3.5e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KER27546.1 - 1e-09 39.1 0.0 3.5e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KER27546.1 - 6.6e-07 29.6 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KER27546.1 - 0.0027 17.3 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain TGT PF01702.18 KER27547.1 - 1.1e-129 432.6 0.0 1.9e-129 431.8 0.0 1.4 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-C2H2_jaz PF12171.8 KER27547.1 - 1.7e-12 47.3 11.5 0.00073 19.8 0.1 5.7 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KER27547.1 - 2.7e-12 46.4 59.5 2.4e-05 24.5 2.4 8.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER27547.1 - 5.4e-07 29.9 64.7 0.054 14.3 1.8 8.9 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER27547.1 - 0.00024 21.4 20.4 0.0011 19.3 0.3 6.3 5 1 0 7 7 7 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KER27547.1 - 0.00027 21.2 17.1 0.053 13.9 0.5 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KER27547.1 - 0.0023 18.3 0.7 0.0023 18.3 0.7 8.3 9 0 0 9 9 9 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KER27547.1 - 0.71 10.6 21.2 9.8 6.9 0.6 5.3 2 2 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KER27547.1 - 5.4 7.4 32.2 1.7 9.0 1.1 6.3 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Glyco_transf_22 PF03901.17 KER27548.1 - 2.8e-37 128.9 5.9 6.3e-31 108.0 2.3 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family zf-RING_2 PF13639.6 KER27549.1 - 2.8e-14 53.2 7.8 1.2e-13 51.2 7.8 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KER27549.1 - 7.8e-11 41.5 3.3 2.1e-10 40.1 3.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KER27549.1 - 4.3e-09 36.1 7.4 1.2e-08 34.7 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER27549.1 - 7.1e-09 35.4 6.8 1.7e-08 34.2 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER27549.1 - 6e-08 32.5 6.8 2.2e-07 30.7 6.8 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER27549.1 - 4e-07 30.0 3.8 1e-06 28.7 3.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KER27549.1 - 8.4e-07 29.2 8.3 3.1e-06 27.4 8.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KER27549.1 - 9.9e-06 25.3 4.1 3.2e-05 23.7 4.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER27549.1 - 0.00032 20.5 4.1 0.0008 19.2 4.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KER27549.1 - 0.00088 18.9 2.7 0.0025 17.4 2.7 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KER27549.1 - 0.011 15.8 1.2 0.029 14.4 1.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atracotoxin PF05353.11 KER27549.1 - 0.036 14.1 0.6 0.12 12.5 0.6 1.8 1 0 0 1 1 1 0 Delta Atracotoxin zf-C3HC4_4 PF15227.6 KER27549.1 - 0.086 13.0 4.8 0.49 10.6 4.9 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KER27549.1 - 0.2 11.5 5.3 0.59 10.0 5.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KER27549.1 - 1.8 8.7 5.6 6.2 6.9 5.6 2.0 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KER27549.1 - 2.1 8.6 9.5 0.79 9.9 5.3 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KER27549.1 - 8.5 6.6 12.3 0.57 10.3 6.6 2.1 2 0 0 2 2 1 0 RING-variant domain RFX_DNA_binding PF02257.15 KER27550.1 - 3.6e-33 114.0 0.1 9.9e-33 112.6 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KER27550.1 - 0.1 13.1 0.1 0.51 10.9 0.1 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like HisKA PF00512.25 KER27550.1 - 0.19 11.8 0.4 0.61 10.2 0.4 1.8 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain CtaG_Cox11 PF04442.14 KER27552.1 - 1.6e-58 197.0 3.6 4.2e-43 147.0 0.6 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein CtaG/Cox11 RVT_1 PF00078.27 KER27553.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleopor_Nup85 PF07575.13 KER27553.1 - 0.067 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Amidohydro_2 PF04909.14 KER27554.1 - 3.7e-12 46.6 0.0 5e-11 42.9 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase GSCFA PF08885.11 KER27554.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 GSCFA family Phage_Gp23 PF10669.9 KER27554.1 - 4.3 7.7 7.7 10 6.5 7.7 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) S_tail_recep_bd PF14928.6 KER27557.1 - 0.13 12.9 0.3 1.3 9.7 0.1 2.1 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain VPS9 PF02204.18 KER27560.1 - 6.4e-22 77.7 0.0 3.2e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KER27560.1 - 2.7e-16 59.6 0.2 1.6e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 KER27560.1 - 1.4e-11 44.1 7.9 2.9e-11 43.1 7.9 1.6 1 0 0 1 1 1 1 A20-like zinc finger MbeD_MobD PF04899.12 KER27560.1 - 0.032 14.3 2.5 0.58 10.3 0.4 2.7 2 0 0 2 2 2 0 MbeD/MobD like ABA_GPCR PF12430.8 KER27561.1 - 1.2e-36 126.1 9.9 1.2e-36 126.1 9.9 2.5 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KER27561.1 - 1.1e-25 89.4 0.1 2.3e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal HMW1C_N PF18071.1 KER27561.1 - 6.8 6.5 7.3 16 5.3 0.2 2.8 3 0 0 3 3 3 0 HMW1C N-terminal F-box-like PF12937.7 KER27562.1 - 0.0067 16.3 0.7 0.017 15.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER27562.1 - 0.035 14.0 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KER27562.1 - 0.13 12.8 4.6 26 5.4 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) C2 PF00168.30 KER27565.1 - 9.3e-52 173.6 0.4 1.2e-20 73.7 0.0 3.8 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.10 KER27565.1 - 1.6e-07 31.2 0.3 8.4e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 KER27565.1 - 3.1e-07 30.0 0.5 0.00052 19.5 0.1 2.3 2 0 0 2 2 2 2 Plant protein of unknown function (DUF639) Pex24p PF06398.11 KER27565.1 - 6.8e-05 22.0 0.4 0.00013 21.1 0.4 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 KER27565.1 - 0.014 15.4 0.7 0.033 14.2 0.7 1.6 1 1 0 1 1 1 0 Reticulon CEP76-C2 PF15627.6 KER27565.1 - 0.1 12.2 0.0 21 4.6 0.0 2.7 3 0 0 3 3 3 0 CEP76 C2 domain DUF4710 PF15828.5 KER27565.1 - 2.8 8.1 5.3 29 4.9 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Med22 PF06179.12 KER27568.1 - 3.9e-16 59.2 2.6 1.7e-08 34.6 0.2 2.2 2 0 0 2 2 2 2 Surfeit locus protein 5 subunit 22 of Mediator complex Aminotran_1_2 PF00155.21 KER27569.1 - 2.1e-50 171.9 0.0 2.5e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KER27569.1 - 0.0049 16.2 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KER27569.1 - 0.016 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V NPDC1 PF06809.11 KER27571.1 - 1.4e-11 44.0 0.0 1.7e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) DUF2140 PF09911.9 KER27571.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) NOA36 PF06524.12 KER27574.1 - 0.036 13.4 5.1 0.063 12.6 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein PSI PF01437.25 KER27574.1 - 0.21 12.2 3.1 0.59 10.7 3.1 1.8 1 1 0 1 1 1 0 Plexin repeat DUF4611 PF15387.6 KER27574.1 - 1.9 8.8 7.0 3.4 7.9 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KER27574.1 - 4.7 7.6 14.3 18 5.8 13.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2_2 PF13465.6 KER27575.1 - 2.8e-16 59.1 36.0 7.2e-06 26.2 2.0 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER27575.1 - 9.5e-11 41.5 45.2 0.003 17.9 3.4 6.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER27575.1 - 1.3e-07 31.8 39.9 0.028 15.2 0.5 6.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER27575.1 - 0.014 15.2 0.8 0.014 15.2 0.8 3.3 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KER27575.1 - 6.6 7.3 14.2 1.6e+04 -3.6 14.2 3.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KER27576.1 - 0.06 13.6 0.5 0.06 13.6 0.5 2.0 2 0 0 2 2 2 0 LIM domain RMI1_C PF16099.5 KER27578.1 - 5e-29 101.0 0.0 7.5e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold RMI1_N PF08585.12 KER27579.1 - 1.1e-31 110.3 0.2 3.7e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 RecQ mediated genome instability protein Atg8 PF02991.16 KER27580.1 - 2.2e-34 117.7 0.0 4.6e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KER27580.1 - 0.0095 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SRCR PF00530.18 KER27582.1 - 1e-33 115.8 8.6 3.3e-14 53.2 0.1 4.2 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain Beta_helix PF13229.6 KER27582.1 - 5.2e-15 55.6 52.8 6.1e-05 22.9 3.6 7.6 4 3 3 8 8 8 5 Right handed beta helix region SRCR_2 PF15494.6 KER27582.1 - 1.5e-08 35.1 8.9 0.04 14.5 0.1 4.2 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain RVT_1 PF00078.27 KER27582.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hepsin-SRCR PF09272.10 KER27582.1 - 0.0044 17.5 0.4 51 4.4 0.0 3.7 3 0 0 3 3 3 0 Hepsin, SRCR domain UL45 PF05473.12 KER27582.1 - 0.039 13.6 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Nop14 PF04147.12 KER27585.1 - 0.0064 14.8 40.9 0.008 14.5 40.9 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.15 KER27585.1 - 0.047 12.5 9.2 0.052 12.3 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KER27585.1 - 0.057 12.8 42.7 0.074 12.5 42.7 1.1 1 0 0 1 1 1 0 SDA1 Linker_histone PF00538.19 KER27586.1 - 1.2e-11 44.8 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Linker_histone PF00538.19 KER27588.1 - 6.9e-29 100.0 0.4 1.6e-28 98.9 0.4 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family AAA_5 PF07728.14 KER27591.1 - 9.2e-06 25.7 0.0 0.0067 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KER27591.1 - 9.6e-06 25.7 0.0 6.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KER27591.1 - 0.00023 21.6 0.0 0.2 12.1 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KER27591.1 - 0.00029 20.8 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 KER27591.1 - 0.00039 20.8 0.0 0.43 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KER27591.1 - 0.00048 20.4 0.1 2.1 8.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KER27591.1 - 0.0005 20.6 0.0 1.1 9.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KER27591.1 - 0.0011 18.9 0.1 0.17 11.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KER27591.1 - 0.0018 18.8 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KER27591.1 - 0.0025 17.5 0.2 0.65 9.8 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 KER27591.1 - 0.011 14.9 0.1 0.027 13.6 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.20 KER27591.1 - 0.019 14.1 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 KER27591.1 - 0.025 14.1 0.0 0.8 9.2 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 KER27591.1 - 0.028 14.6 0.0 2.8 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KER27591.1 - 0.032 14.3 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SRP54 PF00448.22 KER27591.1 - 0.036 13.7 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KER27591.1 - 0.14 11.9 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Importin_rep PF18773.1 KER27591.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat TFIIA PF03153.13 KER27593.1 - 5.2e-06 26.7 13.5 1.3e-05 25.4 13.5 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MT PF12777.7 KER27593.1 - 2e-05 23.8 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor CDC45 PF02724.14 KER27593.1 - 0.0022 16.4 18.9 0.0022 16.4 18.9 1.9 2 0 0 2 2 2 1 CDC45-like protein BAR PF03114.18 KER27593.1 - 0.0033 17.1 7.7 0.0033 17.1 7.7 2.5 2 1 0 2 2 2 1 BAR domain BUD22 PF09073.10 KER27593.1 - 0.0049 16.3 13.0 0.0098 15.3 13.0 1.5 1 0 0 1 1 1 1 BUD22 ATPase_2 PF01637.18 KER27593.1 - 0.0063 16.5 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KER27593.1 - 0.0074 16.7 0.0 0.04 14.3 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KER27593.1 - 0.011 16.2 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ctf8 PF09696.10 KER27593.1 - 0.012 15.9 0.1 1.5 9.1 0.6 2.6 2 0 0 2 2 2 0 Ctf8 AAA_23 PF13476.6 KER27593.1 - 0.62 10.5 0.0 0.62 10.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KER27593.1 - 2.3 7.9 9.3 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Pedibin PF08182.11 KER27593.1 - 2.4 8.0 7.2 0.31 10.9 1.7 2.4 2 0 0 2 2 2 0 Pedibin/Hym-346 family DNA_pol_phi PF04931.13 KER27593.1 - 5.1 5.1 39.9 8.8 4.3 39.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KER27593.1 - 8.6 4.4 31.1 18 3.4 31.1 1.4 1 0 0 1 1 1 0 Nop14-like family SMC_ScpA PF02616.14 KER27596.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Acetyltransf_1 PF00583.25 KER27598.1 - 3.2e-08 33.8 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER27598.1 - 6.2e-06 26.2 0.1 1.7e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KER27598.1 - 1.5e-05 25.3 0.1 3.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER27598.1 - 0.00091 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein VHL PF01847.16 KER27598.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 VHL beta domain Methyltransf_11 PF08241.12 KER27599.1 - 1.7e-08 35.0 0.0 2e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER27599.1 - 5.8e-08 33.3 0.0 1.8e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KER27599.1 - 2.4e-05 25.0 0.0 0.003 18.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER27599.1 - 0.00016 21.5 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KER27599.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NMD3 PF04981.13 KER27602.1 - 4e-73 245.9 10.0 6.1e-73 245.3 10.0 1.3 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 KER27602.1 - 0.088 12.7 3.1 0.29 11.0 2.2 2.4 2 0 0 2 2 2 0 NinF protein DZR PF12773.7 KER27602.1 - 2.7 8.1 17.8 0.37 10.9 5.9 3.1 1 1 2 3 3 3 0 Double zinc ribbon Pkinase PF00069.25 KER27603.1 - 2.2e-34 119.0 0.0 3.3e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER27603.1 - 6.5e-05 22.3 0.0 0.29 10.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase MdcG PF10620.9 KER27603.1 - 0.072 12.9 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG SHMT PF00464.19 KER27606.1 - 6.2e-173 575.0 0.0 9.4e-173 574.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF2464 PF10240.9 KER27606.1 - 3e-12 46.7 0.0 5.4e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 Multivesicular body subunit 12 ARGLU PF15346.6 KER27608.1 - 2.1e-24 86.1 46.3 1.7e-15 57.2 25.9 3.1 2 1 1 3 3 3 2 Arginine and glutamate-rich 1 Ribosomal_60s PF00428.19 KER27608.1 - 7.8 7.2 14.2 23 5.7 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ParcG PF10274.9 KER27609.1 - 1.5e-77 259.9 0.0 1.8e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 KER27609.1 - 0.0046 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 LRR_4 PF12799.7 KER27610.1 - 1.5e-30 104.7 30.6 1.9e-05 25.0 2.0 8.1 2 1 10 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER27610.1 - 1.2e-19 70.5 4.9 3.9e-15 55.8 0.0 3.8 2 1 1 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 KER27610.1 - 5.4e-17 61.3 26.2 2.4e-05 24.0 3.8 5.8 3 2 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KER27610.1 - 0.0026 18.1 16.0 4.6 8.2 0.2 7.4 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 KER27610.1 - 0.0087 16.0 18.8 0.9 9.8 0.1 7.8 9 0 0 9 9 9 2 Leucine Rich repeat Surp PF01805.20 KER27611.1 - 1.2e-16 60.4 0.7 2.6e-16 59.3 0.7 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KER27611.1 - 2.7e-14 53.7 0.8 4.9e-14 52.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SHE3 PF17078.5 KER27611.1 - 0.28 10.9 3.9 0.13 12.0 0.7 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 HLH PF00010.26 KER27612.1 - 2.4e-12 46.6 1.0 5.5e-12 45.4 0.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GspH PF12019.8 KER27612.1 - 0.36 11.3 3.1 18 5.8 0.4 2.6 2 0 0 2 2 2 0 Type II transport protein GspH Foie-gras_1 PF11817.8 KER27617.1 - 3e-47 161.4 2.5 4.1e-45 154.4 2.5 2.3 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KER27617.1 - 5.2e-11 42.4 0.4 1e-10 41.4 0.4 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Gryzun PF07919.12 KER27617.1 - 3.5e-09 36.0 0.5 9.8e-09 34.5 0.1 1.8 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi CBM_14 PF01607.24 KER27617.1 - 0.011 15.8 0.8 5.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain TPR_1 PF00515.28 KER27617.1 - 0.042 13.7 3.9 0.059 13.2 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER27617.1 - 0.15 12.3 4.7 0.2 11.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Arm-DNA-bind_2 PF12167.8 KER27618.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain Spond_N PF06468.13 KER27621.1 - 1.4e-44 152.6 0.0 2.3e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Spondin_N Kunitz_BPTI PF00014.23 KER27621.1 - 9.2e-26 89.9 20.6 8.8e-14 51.5 3.4 3.2 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain TSP_1 PF00090.19 KER27621.1 - 2.1e-15 56.7 33.7 2.4e-08 34.0 5.7 5.0 4 0 0 4 4 4 3 Thrombospondin type 1 domain CRAL_TRIO PF00650.20 KER27622.1 - 3.9e-13 49.4 0.0 8.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Retrotran_gag_2 PF14223.6 KER27622.1 - 0.092 12.4 0.1 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Atg8 PF02991.16 KER27625.1 - 8.9e-19 67.6 0.0 9.5e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KER27625.1 - 0.00025 21.4 0.0 0.00025 21.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Radial_spoke_3 PF06098.11 KER27626.1 - 1e-101 340.0 16.3 2.7e-63 213.9 16.5 2.9 2 1 1 3 3 3 2 Radial spoke protein 3 HrpF PF06266.12 KER27626.1 - 0.5 10.7 2.7 0.42 10.9 0.2 2.0 2 0 0 2 2 2 0 HrpF protein DUF572 PF04502.13 KER27627.1 - 1e-68 232.4 0.4 1.2e-68 232.2 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Mut7-C PF01927.16 KER27627.1 - 0.046 13.8 0.5 0.046 13.8 0.5 2.2 2 1 1 3 3 3 0 Mut7-C RNAse domain Radial_spoke_3 PF06098.11 KER27627.1 - 0.19 10.9 10.4 0.3 10.3 10.4 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 HrpJ PF07201.11 KER27627.1 - 0.72 10.1 12.8 1.1 9.5 12.8 1.2 1 0 0 1 1 1 0 HrpJ-like domain V_ATPase_I PF01496.19 KER27627.1 - 0.87 7.4 3.1 1.1 7.1 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SET PF00856.28 KER27628.1 - 8.7e-07 29.5 0.0 2.2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 SET domain Ribosomal_L3 PF00297.22 KER27629.1 - 2.3e-07 30.2 3.6 1.4e-05 24.2 3.6 2.7 2 1 1 3 3 3 2 Ribosomal protein L3 SAPS PF04499.15 KER27630.1 - 3.5e-36 125.0 0.0 2.9e-22 79.1 0.0 3.4 3 0 0 3 3 3 3 SIT4 phosphatase-associated protein RRN3 PF05327.11 KER27630.1 - 3.1 6.2 7.4 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 VHS PF00790.19 KER27634.1 - 2.5e-22 79.3 0.7 6.3e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 VHS domain GGA_N-GAT PF18308.1 KER27634.1 - 7.9e-17 60.6 1.5 1.6e-16 59.6 1.5 1.5 1 0 0 1 1 1 1 GGA N-GAT domain Alpha_adaptinC2 PF02883.20 KER27634.1 - 4.5e-09 36.6 0.0 9.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KER27634.1 - 2.2e-07 31.1 3.3 2.7e-07 30.8 0.8 2.5 2 0 0 2 2 2 1 GAT domain Csm1_N PF18504.1 KER27634.1 - 0.0021 18.3 2.6 0.0041 17.4 2.6 1.4 1 0 0 1 1 1 1 Csm1 N-terminal domain MutS_III PF05192.18 KER27634.1 - 1.3 9.2 4.2 3.2 7.9 4.2 1.7 1 1 0 1 1 1 0 MutS domain III HTH_11 PF08279.12 KER27637.1 - 0.035 14.0 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 HTH domain PX PF00787.24 KER27639.1 - 7.7e-14 51.6 3.5 1.3e-13 50.9 2.2 2.1 2 0 0 2 2 2 1 PX domain PXA PF02194.15 KER27639.1 - 3.9e-06 26.9 0.3 0.0011 19.0 0.3 2.9 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KER27639.1 - 0.013 16.1 0.0 0.049 14.2 0.0 2.0 2 0 0 2 2 2 0 Sorting nexin C terminal Phage_DNA_bind PF02303.17 KER27641.1 - 0.076 13.3 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 Helix-destabilising protein Cdh1_DBD_1 PF18196.1 KER27643.1 - 0.0065 16.8 0.5 0.0065 16.8 0.5 4.3 3 1 2 5 5 5 1 Chromodomain helicase DNA-binding domain 1 APG6_N PF17675.1 KER27643.1 - 0.033 14.7 2.3 0.033 14.7 2.3 5.8 3 1 3 6 6 6 0 Apg6 coiled-coil region DUF1406 PF07190.11 KER27643.1 - 0.11 12.5 1.4 0.23 11.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) ATG16 PF08614.11 KER27643.1 - 0.2 11.9 67.8 0.21 11.8 18.3 5.3 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KER27643.1 - 0.47 9.7 40.0 0.53 9.6 3.2 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KER27643.1 - 0.7 7.3 49.8 0.27 8.7 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KER27643.1 - 0.85 8.4 57.8 1.3 7.8 5.5 3.5 2 2 1 3 3 3 0 Spc7 kinetochore protein DUF5082 PF16888.5 KER27643.1 - 1 9.6 40.9 2.6 8.4 0.4 5.7 5 1 1 6 6 6 0 Domain of unknown function (DUF5082) Rop-like PF05082.13 KER27643.1 - 2.8 7.8 9.5 4.4 7.2 0.1 4.6 3 1 1 4 4 4 0 Rop-like DUF1664 PF07889.12 KER27643.1 - 4.2 7.4 38.3 0.73 9.9 4.1 5.8 3 1 2 6 6 6 0 Protein of unknown function (DUF1664) Transketolase_N PF00456.21 KER27644.1 - 9.2e-47 159.6 0.0 1.8e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KER27644.1 - 3.6e-34 118.0 0.0 5.9e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KER27644.1 - 7e-33 113.2 0.1 7.7e-32 109.8 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 KER27644.1 - 4.6e-09 35.7 0.0 7.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KER27644.1 - 5.2e-05 23.1 0.1 0.00043 20.1 0.1 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KER27644.1 - 6.2e-05 22.3 0.2 0.0045 16.2 0.1 2.7 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 KER27644.1 - 0.0024 16.7 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain zf-met PF12874.7 KER27645.1 - 3.9e-07 30.2 0.9 3.9e-07 30.2 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER27645.1 - 6.4e-05 23.1 1.3 6.4e-05 23.1 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KER27645.1 - 0.00013 21.6 0.2 0.00032 20.4 0.2 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_6 PF13912.6 KER27645.1 - 0.1 12.6 0.9 0.18 11.8 0.9 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger PDZ PF00595.24 KER27647.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER27647.1 - 4.5e-05 23.2 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER27647.1 - 0.00048 20.4 0.0 0.00073 19.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DNA_pol_phi PF04931.13 KER27648.1 - 0.0025 16.0 22.7 0.0028 15.9 22.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi NOA36 PF06524.12 KER27648.1 - 0.017 14.5 22.1 0.02 14.3 22.1 1.1 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 KER27648.1 - 0.018 14.8 4.7 0.021 14.5 4.7 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2796 PF10986.8 KER27648.1 - 0.078 12.9 1.7 0.09 12.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SAPS PF04499.15 KER27648.1 - 0.086 11.6 1.4 0.087 11.6 1.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 KER27648.1 - 0.21 10.8 7.5 0.23 10.6 7.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 KER27648.1 - 0.32 10.4 13.5 0.33 10.4 13.5 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KER27648.1 - 0.43 10.4 12.7 0.49 10.3 12.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 KER27648.1 - 0.52 8.5 16.2 0.52 8.5 16.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KER27648.1 - 0.54 8.5 12.4 0.61 8.3 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KER27648.1 - 1.2 7.6 14.3 1.3 7.5 14.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KER27648.1 - 1.3 8.3 11.4 1.3 8.3 11.4 1.1 1 0 0 1 1 1 0 BUD22 DUF4637 PF15470.6 KER27648.1 - 1.5 8.5 4.6 1.9 8.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) IFT57 PF10498.9 KER27648.1 - 1.6 7.6 6.7 1.8 7.5 6.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2722 PF10846.8 KER27648.1 - 1.7 7.5 13.2 2 7.3 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.9 KER27648.1 - 2 7.5 32.7 2.4 7.2 32.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pes-10 PF07149.11 KER27648.1 - 2.1 7.3 10.6 2.2 7.3 10.6 1.1 1 0 0 1 1 1 0 Pes-10 PPP4R2 PF09184.11 KER27648.1 - 4.7 6.7 16.9 5.2 6.6 16.9 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 KER27648.1 - 6.6 6.9 24.0 7.9 6.7 24.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Rhabdo_ncap PF00945.18 KER27648.1 - 6.8 5.5 9.9 8.1 5.2 9.9 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CobT PF06213.12 KER27648.1 - 7 5.9 12.7 9 5.6 12.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 KER27648.1 - 9.4 4.2 11.3 12 3.9 11.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aha1_N PF09229.11 KER27649.1 - 5.8e-35 120.5 2.7 1.2e-33 116.2 1.7 2.6 2 1 1 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KER27649.1 - 1.4e-15 57.6 0.0 3.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RVT_1 PF00078.27 KER27650.1 - 7.2e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP12 PF07542.11 KER27651.1 - 1.6e-37 128.4 0.1 2.3e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein PCNP PF15473.6 KER27653.1 - 1.3e-20 74.7 0.3 1.9e-20 74.2 0.3 1.2 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family Chitin_synth_1N PF08407.11 KER27653.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Chitin synthase N-terminal FXa_inhibition PF14670.6 KER27656.1 - 0.03 14.6 0.8 0.074 13.4 0.8 1.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 KER27656.1 - 0.27 11.6 1.8 0.69 10.3 1.8 1.7 1 0 0 1 1 1 0 EGF-like domain DUF2451 PF10474.9 KER27657.1 - 1.5e-87 293.3 0.2 5.4e-87 291.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KER27657.1 - 1.2e-50 172.4 4.8 2.7e-50 171.3 4.8 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex MitMem_reg PF13012.6 KER27657.1 - 0.089 13.2 0.7 26 5.3 0.2 4.1 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF3510 PF12022.8 KER27657.1 - 0.1 12.9 0.1 4.6 7.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) UQ_con PF00179.26 KER27658.1 - 3.4e-45 153.1 0.0 4.7e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KER27658.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KER27658.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER27658.1 - 0.018 15.3 0.1 0.038 14.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain DUF4218 PF13960.6 KER27659.1 - 0.019 14.6 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Peptidase_S8 PF00082.22 KER27661.1 - 1.3e-29 103.5 0.3 1.8e-29 103.0 0.3 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KER27661.1 - 6.5e-17 61.3 0.1 2.5e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 Proprotein convertase P-domain GTP_EFTU PF00009.27 KER27664.1 - 1.2e-34 119.6 0.0 1.2e-34 119.6 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KER27664.1 - 4.6e-16 58.9 0.4 1.6e-15 57.1 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 KER27664.1 - 1.7e-13 50.3 0.0 4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KER27664.1 - 2.9e-11 43.6 2.4 3.6e-06 27.3 0.1 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KER27664.1 - 2.8e-07 30.6 0.0 1.1e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KER27664.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KER27664.1 - 0.0046 16.8 0.2 0.039 13.7 0.1 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KER27664.1 - 0.026 14.4 0.1 0.33 10.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KER27664.1 - 0.061 13.6 1.1 0.3 11.4 0.0 2.8 3 1 0 3 3 3 0 AAA domain LicD PF04991.13 KER27667.1 - 3.8e-08 33.8 0.1 5.8e-07 29.9 0.0 2.2 1 1 1 2 2 2 1 LicD family PMP22_Claudin PF00822.20 KER27668.1 - 0.026 14.4 1.2 0.037 13.9 1.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Eapp_C PF10238.9 KER27669.1 - 0.038 14.1 0.9 0.092 12.8 0.9 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 KER27669.1 - 0.15 12.3 0.8 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.6 KER27669.1 - 0.23 11.4 3.3 11 6.1 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_12 PF17976.1 KER27669.1 - 0.67 10.3 0.0 0.67 10.3 0.0 2.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Peptidase_S9 PF00326.21 KER27670.1 - 1.3e-49 168.5 0.9 2.1e-49 167.9 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KER27670.1 - 1.4e-44 152.3 0.1 1.9e-44 151.9 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DLH PF01738.18 KER27670.1 - 1.4e-05 24.8 0.0 5.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KER27670.1 - 0.0034 18.0 0.2 0.028 15.0 0.0 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family RVT_1 PF00078.27 KER27673.1 - 5.9e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IATP PF04568.12 KER27674.1 - 3.7e-15 56.1 3.8 4.2e-15 56.0 3.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PEPCK_GTP PF00821.18 KER27676.1 - 1.2e-158 527.6 0.0 1.5e-158 527.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KER27676.1 - 2.7e-92 308.3 0.0 3.7e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain S-methyl_trans PF02574.16 KER27677.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase TRAM_LAG1_CLN8 PF03798.16 KER27678.1 - 3.6e-23 82.3 23.4 1.4e-19 70.6 8.8 2.4 2 0 0 2 2 2 2 TLC domain DUF2740 PF10872.8 KER27678.1 - 0.099 12.6 0.0 58 3.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2740) DUF4455 PF14643.6 KER27680.1 - 1.5e-89 300.8 20.4 1.5e-89 300.8 20.4 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 KER27680.1 - 6.2e-22 78.3 1.3 6.2e-22 78.3 1.3 4.9 4 2 2 6 6 6 1 Domain of unknown function (DUF4456) RAC_head PF16717.5 KER27680.1 - 0.55 11.2 3.6 5.6 8.0 0.0 4.2 4 0 0 4 4 4 0 Ribosome-associated complex head domain DUF948 PF06103.11 KER27680.1 - 0.74 10.1 3.8 2.6 8.4 0.1 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sds3 PF08598.11 KER27680.1 - 6.2 6.7 15.2 0.61 10.1 0.7 4.9 3 2 2 5 5 5 0 Sds3-like REV1_C PF16727.5 KER27681.1 - 0.034 14.5 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain DUF3504 PF12012.8 KER27681.1 - 0.063 13.2 0.5 0.063 13.2 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) DUF1957 PF09210.11 KER27681.1 - 8.4 6.9 9.8 0.62 10.5 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Tubulin_C PF03953.17 KER27682.1 - 1.2e-22 80.4 0.0 2.8e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KER27682.1 - 1.2e-21 77.8 0.0 3.4e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KER27682.1 - 0.00016 21.4 0.0 0.00048 19.9 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Get5_bdg PF16843.5 KER27683.1 - 0.12 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein tRNA-synt_1 PF00133.22 KER27685.1 - 6.9e-242 804.0 0.0 3.4e-194 646.5 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KER27685.1 - 4e-34 117.8 0.7 1.1e-33 116.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KER27685.1 - 8e-14 51.2 0.0 0.0001 21.2 0.0 4.7 4 0 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KER27685.1 - 2.1e-07 30.7 4.9 4.6e-07 29.5 0.0 3.1 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KER27685.1 - 3.7e-05 23.2 0.0 0.32 10.3 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KER27685.1 - 0.00021 20.7 0.0 0.86 8.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Jag_N PF14804.6 KER27685.1 - 0.0018 18.6 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 1 Jag N-terminus tRNA-synt_1f PF01921.18 KER27685.1 - 0.056 12.3 0.0 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KER27686.1 - 3.2e-63 214.0 0.0 3.5e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KER27686.1 - 6.5e-05 21.8 0.0 0.3 9.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Jag_N PF14804.6 KER27686.1 - 0.017 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Jag N-terminus tRNA-synt_1e PF01406.19 KER27686.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KER27686.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (W and Y) MRP-L28 PF09812.9 KER27688.1 - 2.1e-27 96.2 9.0 2.1e-27 96.2 9.0 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal protein L28 SspB PF04386.13 KER27689.1 - 0.034 14.0 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B EGF PF00008.27 KER27690.1 - 1e-05 25.7 18.6 0.0018 18.5 6.5 2.6 2 0 0 2 2 2 2 EGF-like domain SEA PF01390.20 KER27690.1 - 9.6e-05 22.4 0.8 0.00017 21.6 0.0 1.7 2 0 0 2 2 2 1 SEA domain EGF_2 PF07974.13 KER27690.1 - 0.0019 18.5 20.3 0.018 15.4 6.2 2.4 2 0 0 2 2 2 2 EGF-like domain EGF_3 PF12947.7 KER27690.1 - 0.012 15.7 4.3 0.012 15.7 4.3 2.6 2 0 0 2 2 2 0 EGF domain DUF3844 PF12955.7 KER27690.1 - 0.098 12.8 0.3 0.098 12.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) hEGF PF12661.7 KER27690.1 - 0.13 12.9 16.4 0.34 11.6 3.7 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.15 KER27690.1 - 3.1 8.1 15.1 0.052 13.8 3.5 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain DUF3695 PF12494.8 KER27691.1 - 3.8e-05 23.5 0.2 3.8e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Citrate_bind PF16114.5 KER27692.1 - 7.9e-88 292.6 0.0 1.1e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KER27692.1 - 0.00036 20.2 0.1 0.69 9.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain DUF5131 PF07505.11 KER27692.1 - 0.2 11.1 0.5 0.36 10.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Tetraspanin PF00335.20 KER27694.1 - 0.028 14.1 17.1 0.042 13.6 17.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3139 PF11337.8 KER27694.1 - 0.032 14.9 0.2 0.032 14.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) UPF0114 PF03350.16 KER27694.1 - 2.9 8.1 9.5 0.14 12.4 1.8 2.2 1 1 0 2 2 2 0 Uncharacterized protein family, UPF0114 Tetraspanin PF00335.20 KER27695.1 - 0.065 12.9 0.1 0.068 12.9 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Tetraspanin PF00335.20 KER27696.1 - 2.7e-07 30.6 0.9 3.2e-06 27.0 0.9 1.9 1 1 0 1 1 1 1 Tetraspanin family Ribosomal_L6e PF01159.19 KER27698.1 - 3.5e-25 88.7 0.1 3.5e-25 88.7 0.1 6.4 9 0 0 9 9 9 1 Ribosomal protein L6e EF-hand_7 PF13499.6 KER27698.1 - 4.4e-06 27.0 0.0 1.4e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER27698.1 - 0.00045 19.9 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KER27698.1 - 0.00057 19.3 0.0 0.0019 17.6 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.6 KER27698.1 - 0.011 16.0 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Bravo_FIGEY PF13882.6 KER27699.1 - 1.4e-19 71.2 6.6 3.1e-19 70.1 6.6 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region Ig_3 PF13927.6 KER27700.1 - 5.2e-27 94.3 0.8 4.1e-08 33.7 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 KER27700.1 - 3.4e-19 68.7 0.0 1.3e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 KER27700.1 - 1.6e-13 50.7 6.8 0.0011 19.1 0.0 7.3 6 2 2 8 8 8 3 Immunoglobulin V-set domain Ig_2 PF13895.6 KER27700.1 - 5.4e-13 49.1 0.5 0.0047 17.2 0.0 5.0 4 1 1 5 5 5 3 Immunoglobulin domain ig PF00047.25 KER27700.1 - 5.5e-13 48.9 0.0 0.0079 16.4 0.0 4.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 KER27700.1 - 2.3e-05 23.9 0.0 1.5 8.4 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KER27700.1 - 0.0006 19.8 0.0 1.1 9.3 0.0 3.5 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Cadherin_C_2 PF16492.5 KER27700.1 - 0.39 11.5 4.6 0.81 10.5 0.0 3.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 KER27700.1 - 1.3 10.0 0.0 1.3 10.0 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain EppA_BapA PF07268.11 KER27702.1 - 0.095 12.7 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 Exported protein precursor (EppA/BapA) Glyco_hydro_125 PF06824.11 KER27704.1 - 0.015 14.2 0.1 0.035 13.0 0.0 1.5 2 0 0 2 2 2 0 Metal-independent alpha-mannosidase (GH125) Ras PF00071.22 KER27706.1 - 3e-48 163.5 0.0 3.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER27706.1 - 2.9e-28 98.5 0.0 4.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER27706.1 - 5.9e-09 35.6 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER27706.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER27706.1 - 0.0045 16.5 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KER27706.1 - 0.019 14.5 0.0 0.058 12.9 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER27706.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KER27708.1 - 1.2e-23 83.5 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER27708.1 - 0.00041 20.5 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase bZIP_2 PF07716.15 KER27709.1 - 2.2e-06 27.7 3.2 3.9e-06 26.8 3.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper AAA_6 PF12774.7 KER27710.1 - 1.8e-144 480.7 3.0 1.6e-143 477.6 0.9 3.3 4 1 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KER27710.1 - 4.8e-138 461.3 7.4 4.8e-138 461.3 7.4 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KER27710.1 - 2.9e-113 379.0 13.6 8.1e-107 357.8 10.9 5.3 5 1 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KER27710.1 - 7.7e-107 356.5 2.6 5.2e-106 353.7 0.1 3.6 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER27710.1 - 2.1e-98 329.3 1.2 1.2e-96 323.5 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER27710.1 - 3.8e-89 297.6 0.0 2.3e-88 295.0 0.1 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER27710.1 - 3e-72 241.9 0.7 2.7e-69 232.3 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER27710.1 - 3.7e-60 202.4 0.9 9.3e-60 201.2 0.9 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER27710.1 - 2.2e-56 191.3 8.7 4e-56 190.5 8.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER27710.1 - 1.5e-47 160.6 0.1 6.9e-42 142.3 0.0 4.4 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KER27710.1 - 2.8e-30 105.1 0.2 1.1e-29 103.1 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER27710.1 - 2.5e-22 79.4 0.0 5.2e-12 45.9 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER27710.1 - 1.6e-21 76.4 0.2 1e-20 73.8 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KER27710.1 - 6.5e-10 39.5 0.2 0.0027 18.1 0.0 4.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER27710.1 - 7.5e-07 29.5 1.4 0.14 12.4 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 KER27710.1 - 2.3e-05 24.9 0.1 5.3 7.6 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 KER27710.1 - 8.6e-05 23.0 0.2 0.21 12.0 0.0 4.8 5 0 0 5 5 3 1 AAA ATPase domain Mg_chelatase PF01078.21 KER27710.1 - 0.0034 16.8 0.1 0.11 11.9 0.0 3.3 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI YscO-like PF16789.5 KER27710.1 - 0.03 14.3 24.0 0.11 12.5 7.3 3.1 2 0 0 2 2 2 0 YscO-like protein T2SSE PF00437.20 KER27710.1 - 0.036 13.1 0.3 7.5 5.5 0.0 3.4 3 0 0 3 3 3 0 Type II/IV secretion system protein TsaE PF02367.17 KER27710.1 - 0.069 13.2 1.5 2.7 8.0 0.0 3.5 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KER27710.1 - 0.081 13.1 0.0 31 4.7 0.0 3.5 3 0 0 3 3 2 0 AAA domain DUF45 PF01863.17 KER27710.1 - 0.087 12.9 1.6 0.26 11.3 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF45 IstB_IS21 PF01695.17 KER27710.1 - 0.097 12.4 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 1 0 IstB-like ATP binding protein CbiA PF01656.23 KER27710.1 - 0.19 11.8 0.3 3.2 7.8 0.0 3.4 3 0 0 3 3 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KMP11 PF03037.16 KER27710.1 - 0.32 11.8 5.2 5.2 7.9 0.0 3.8 3 0 0 3 3 2 0 Kinetoplastid membrane protein 11 Mcm10 PF09332.11 KER27710.1 - 0.65 9.4 8.0 1.9 7.8 8.0 1.7 1 0 0 1 1 1 0 Mcm10 replication factor AAA_24 PF13479.6 KER27710.1 - 0.76 9.5 4.3 30 4.3 0.1 3.7 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 KER27710.1 - 1.3 9.3 3.1 14 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhaP_Bmeg PF09602.10 KER27710.1 - 5.2 7.0 11.8 0.57 10.1 1.2 4.2 3 0 0 3 3 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Exonuc_VII_L PF02601.15 KER27710.1 - 6.3 6.3 27.6 0.011 15.4 0.5 5.1 5 0 0 5 5 5 0 Exonuclease VII, large subunit tRNA-synt_1b PF00579.25 KER27711.1 - 4.6e-47 160.7 0.0 3.3e-46 158.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MBOAT PF03062.19 KER27714.1 - 3e-36 125.5 1.7 5.4e-36 124.7 1.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family V_ATPase_I PF01496.19 KER27714.1 - 0.0033 15.4 0.7 0.0047 14.9 0.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family tRNA-synt_2 PF00152.20 KER27716.1 - 9.7e-67 225.3 0.0 2e-66 224.2 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KER27716.1 - 7.6e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KER27716.1 - 0.0014 18.2 0.0 0.15 11.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) LRR_9 PF14580.6 KER27718.1 - 6.8e-36 123.4 0.2 1.2e-35 122.6 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat GYF PF02213.16 KER27718.1 - 7.4e-13 47.9 0.0 1.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 GYF domain LRR_8 PF13855.6 KER27718.1 - 0.079 12.7 0.7 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 Leucine rich repeat DUF3153 PF11353.8 KER27721.1 - 0.027 14.0 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Prominin PF05478.11 KER27722.1 - 7e-07 27.6 8.5 0.0073 14.3 0.6 4.7 4 2 0 4 4 4 3 Prominin DUF2627 PF11118.8 KER27722.1 - 0.0082 16.7 2.6 0.17 12.4 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2627) Wzy_C_2 PF11846.8 KER27722.1 - 0.036 14.0 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Glucos_trans_II PF14264.6 KER27722.1 - 0.09 12.1 0.1 0.09 12.1 0.1 2.8 3 0 0 3 3 3 0 Glucosyl transferase GtrII Adeno_E3_CR2 PF02439.15 KER27722.1 - 0.16 11.7 0.5 0.66 9.8 0.5 2.1 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MscS_TM PF12794.7 KER27722.1 - 9.2 5.0 14.4 5 5.9 0.1 3.5 3 1 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 GOLD_2 PF13897.6 KER27723.1 - 4.3e-07 30.5 0.0 6.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking CRAL_TRIO PF00650.20 KER27723.1 - 0.15 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain C1q PF00386.21 KER27723.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 C1q domain CRAL_TRIO PF00650.20 KER27725.1 - 6e-30 104.1 0.0 9.8e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KER27725.1 - 0.02 15.1 0.2 0.038 14.2 0.2 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Filament PF00038.21 KER27726.1 - 4.6e-40 138.1 68.6 4e-39 135.0 68.6 2.1 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 KER27726.1 - 4e-10 40.0 0.0 8.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain Fib_alpha PF08702.10 KER27726.1 - 0.0077 16.4 46.8 0.013 15.7 11.7 5.1 2 1 2 5 5 5 2 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KER27726.1 - 0.19 12.2 70.3 0.34 11.4 30.8 3.5 1 1 3 4 4 4 0 Fez1 GAS PF13851.6 KER27726.1 - 1.4 8.2 69.6 0.62 9.4 18.8 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding NFRKB_winged PF14465.6 KER27726.1 - 6.9 6.9 7.3 4.9 7.4 0.2 3.5 3 1 0 3 3 3 0 NFRKB Winged Helix-like Spc7 PF08317.11 KER27726.1 - 8.5 5.2 66.7 4 6.2 14.5 3.6 1 1 1 3 3 3 0 Spc7 kinetochore protein Lebercilin PF15619.6 KER27726.1 - 9.3 5.9 72.6 0.85 9.2 18.5 4.3 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease SNARE PF05739.19 KER27729.1 - 1e-07 31.9 11.6 1e-07 31.9 11.6 2.9 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KER27729.1 - 1.4e-06 28.6 6.1 1.4e-06 28.6 6.1 2.2 2 0 0 2 2 2 1 Syntaxin-like protein KLRAQ PF10205.9 KER27729.1 - 0.014 15.7 1.4 0.024 14.9 0.1 2.1 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4988 PF16378.5 KER27729.1 - 0.072 12.8 0.4 0.072 12.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function Orf78 PF06024.12 KER27729.1 - 0.12 12.6 1.6 0.22 11.9 1.0 1.7 1 1 0 1 1 1 0 Orf78 (ac78) Cadherin PF00028.17 KER27730.1 - 1e-23 83.6 0.1 3.8e-07 30.4 0.0 4.7 4 0 0 4 4 4 4 Cadherin domain Agouti PF05039.12 KER27730.1 - 0.045 14.5 0.5 0.045 14.5 0.5 2.2 2 0 0 2 2 2 0 Agouti protein EphA2_TM PF14575.6 KER27730.1 - 0.23 12.4 1.4 0.44 11.5 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin PF00028.17 KER27731.1 - 4.3e-57 190.6 1.1 1.8e-13 50.7 0.0 8.1 6 2 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 KER27731.1 - 9.2e-10 38.2 0.1 0.00015 21.5 0.0 5.4 5 1 0 5 5 5 2 Cadherin-like CDK5_activator PF03261.15 KER27734.1 - 2.1e-59 201.9 12.3 4.1e-47 161.5 7.3 3.0 2 1 0 2 2 2 2 Cyclin-dependent kinase 5 activator protein RRM_1 PF00076.22 KER27735.1 - 3.7e-35 119.6 0.0 4e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER27735.1 - 2.5e-07 30.7 0.3 0.0089 16.1 0.0 2.8 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KER27735.1 - 0.02 14.9 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif tRNA-synt_2 PF00152.20 KER27736.1 - 4.8e-77 259.1 0.0 6.2e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KER27736.1 - 7.1e-08 32.3 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KER27736.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) MFS_1 PF07690.16 KER27738.1 - 1.6e-23 83.2 34.0 4.7e-17 61.9 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 KER27738.1 - 4.4 7.0 9.5 4.4 7.0 1.2 2.6 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Kunitz_BPTI PF00014.23 KER27740.1 - 8.6e-22 77.1 5.3 5.1e-15 55.4 1.3 2.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 KER27741.1 - 8e-15 54.8 8.5 8e-15 54.8 8.5 1.7 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Glyco_hydro_20 PF00728.22 KER27742.1 - 6.3e-165 548.8 0.0 5.2e-82 276.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KER27742.1 - 2.5e-17 63.8 0.0 1.7e-09 38.5 0.0 2.7 2 1 0 2 2 2 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KER27742.1 - 2.8e-08 34.6 0.0 0.00041 21.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 AP_endonuc_2 PF01261.24 KER27742.1 - 0.067 12.6 0.0 12 5.3 0.0 3.0 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Glyoxalase PF00903.25 KER27742.1 - 0.11 12.7 0.0 34 4.7 0.0 3.0 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ETC_C1_NDUFA5 PF04716.14 KER27743.1 - 2.4e-18 65.7 0.8 5.2e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region FragX_IP PF05994.11 KER27744.1 - 0 1162.2 1.8 0 1162.1 0.0 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 KER27744.1 - 1.1e-08 34.7 6.4 2.5e-08 33.5 6.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) AA_permease_2 PF13520.6 KER27745.1 - 6.6e-14 51.6 17.7 2.2e-13 49.8 0.3 2.2 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KER27745.1 - 0.01 14.5 15.6 0.0058 15.3 10.9 2.2 1 1 1 2 2 2 0 Amino acid permease DUF3165 PF11364.8 KER27745.1 - 1.7 9.0 17.2 2.8 8.4 6.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Tmemb_18A PF09771.9 KER27745.1 - 4.9 7.6 6.8 6.6 7.2 2.6 2.3 2 0 0 2 2 2 0 Transmembrane protein 188 PrgI PF12666.7 KER27745.1 - 5.8 7.7 15.3 3.7 8.3 3.6 2.4 2 0 0 2 2 2 0 PrgI family protein PsbN PF02468.15 KER27745.1 - 6.3 6.7 0.0 6.3 6.7 0.0 4.4 4 2 2 6 6 6 0 Photosystem II reaction centre N protein (psbN) HEAT PF02985.22 KER27747.1 - 0.12 12.7 0.0 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat RTC PF01137.21 KER27748.1 - 1.2e-41 142.3 0.0 1.5e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KER27748.1 - 1.4e-29 102.6 0.0 2.6e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Macoilin PF09726.9 KER27749.1 - 3e-86 290.5 72.8 1.5e-53 182.5 26.8 4.6 3 1 0 4 4 4 3 Macoilin family CALCOCO1 PF07888.11 KER27749.1 - 0.00012 21.2 8.2 0.00012 21.2 8.2 2.2 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0242 PF06785.11 KER27749.1 - 0.001 19.2 5.4 0.001 19.2 5.4 2.7 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus CENP-T_C PF15511.6 KER27749.1 - 0.011 15.8 0.3 0.11 12.7 0.1 2.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold ATG16 PF08614.11 KER27749.1 - 0.03 14.5 62.4 0.13 12.5 15.8 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KER27749.1 - 0.26 10.7 32.0 0.48 9.8 8.2 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF1640 PF07798.11 KER27749.1 - 0.38 10.8 20.0 0.016 15.2 9.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SURF2 PF05477.11 KER27754.1 - 1.5e-05 24.9 0.2 3.1e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Miff PF05644.11 KER27755.1 - 3.2e-09 36.8 5.6 6e-09 36.0 5.6 1.4 1 1 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff Phage_cap_E PF03864.15 KER27755.1 - 0.057 12.6 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage major capsid protein E LUC7 PF03194.15 KER27759.1 - 7.2e-68 229.0 11.3 2.3e-67 227.3 10.3 2.2 1 1 0 1 1 1 1 LUC7 N_terminus Seryl_tRNA_N PF02403.22 KER27759.1 - 0.0026 18.0 5.6 0.0086 16.3 5.6 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CP12 PF02672.15 KER27759.1 - 0.35 11.7 0.2 0.35 11.7 0.2 3.1 3 0 0 3 3 3 0 CP12 domain ArAE_2_N PF10337.9 KER27759.1 - 2 7.4 8.6 0.025 13.6 1.2 1.5 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Exo_endo_phos_2 PF14529.6 KER27761.1 - 0.019 14.8 0.3 0.036 13.9 0.3 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase PP-binding PF00550.25 KER27762.1 - 2.1e-12 47.2 0.1 2.7e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site IBN_N PF03810.19 KER27763.1 - 9.9e-08 31.8 0.1 1.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF4706 PF15797.5 KER27763.1 - 0.077 13.5 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) Clathrin PF00637.20 KER27764.1 - 7.6e-12 45.3 28.8 0.0041 17.0 0.1 8.9 7 4 3 10 10 10 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KER27764.1 - 1.9e-10 40.9 0.1 0.039 14.2 0.0 5.9 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER27764.1 - 5.4e-07 30.2 1.2 0.031 15.1 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KER27764.1 - 6.8e-05 22.1 21.2 0.018 14.1 0.7 5.5 4 1 1 5 5 5 4 Coatomer WD associated region eIF2A PF08662.11 KER27764.1 - 0.0053 16.7 0.1 1 9.2 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_11 PF13414.6 KER27764.1 - 0.085 12.5 2.6 16 5.2 0.1 5.6 5 0 0 5 5 5 0 TPR repeat Phage_Cox PF10743.9 KER27764.1 - 0.12 12.5 4.1 5.9 7.1 0.0 4.3 4 0 0 4 4 4 0 Regulatory phage protein cox TPR_1 PF00515.28 KER27764.1 - 0.15 12.0 32.2 0.39 10.6 0.5 10.3 12 2 1 13 13 13 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER27764.1 - 0.32 11.3 31.4 0.11 12.7 0.5 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER27764.1 - 3.1 8.0 26.0 40 4.6 0.3 10.4 10 2 2 12 12 12 0 Tetratricopeptide repeat SNF PF00209.18 KER27765.1 - 1.4e-49 169.2 16.8 1.6e-32 112.9 2.5 3.1 1 1 2 3 3 3 3 Sodium:neurotransmitter symporter family ECH_1 PF00378.20 KER27765.1 - 1.3e-35 123.0 0.0 2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER27765.1 - 1.3e-21 77.5 0.0 2.6e-21 76.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 KER27765.1 - 3.1e-14 52.9 0.2 1.9e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 Acyl CoA binding protein Exo_endo_phos_2 PF14529.6 KER27765.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase STOP PF05217.12 KER27766.1 - 0.48 10.8 2.9 2.8 8.3 0.3 2.2 2 0 0 2 2 2 0 STOP protein RMP PF14996.6 KER27768.1 - 1.1e-32 113.4 9.6 1.3e-32 113.1 9.6 1.1 1 0 0 1 1 1 1 Retinal Maintenance BING4CT PF08149.11 KER27769.1 - 8e-33 112.1 0.0 5.7e-31 106.2 0.0 3.0 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KER27769.1 - 4.1e-07 30.6 1.8 0.0005 20.8 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER27769.1 - 0.041 14.2 0.0 20 5.6 0.0 3.8 2 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Gb3_synth PF04572.12 KER27769.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Nup160 PF11715.8 KER27769.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 7tm_1 PF00001.21 KER27771.1 - 1.5e-08 34.3 16.2 1.5e-08 34.3 14.3 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KER27771.1 - 4.9e-05 23.2 2.4 0.00013 21.9 2.4 1.7 1 0 0 1 1 1 1 Olfactory receptor Serpentine_r_xa PF03383.15 KER27771.1 - 0.018 15.0 5.9 0.052 13.5 5.8 1.9 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa DUF3938 PF13074.6 KER27772.1 - 0.13 12.5 5.8 0.083 13.1 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) ABC2_membrane_5 PF13346.6 KER27772.1 - 0.14 11.7 15.9 0.18 11.4 15.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Fungal_trans PF04082.18 KER27772.1 - 0.15 11.1 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain ECSCR PF15820.5 KER27772.1 - 0.25 11.2 10.1 0.82 9.5 0.8 2.6 1 1 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF5392 PF17370.2 KER27772.1 - 0.26 11.3 3.3 0.37 10.9 2.6 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5392) PAG PF15347.6 KER27772.1 - 0.27 10.2 0.6 0.38 9.7 0.6 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DUF2070 PF09843.9 KER27772.1 - 6.4 4.9 14.1 7.9 4.6 14.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4381 PF14316.6 KER27772.1 - 7.1 6.9 5.1 6.6 7.0 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TssN PF17555.2 KER27772.1 - 8.1 5.7 10.6 2.4 7.5 5.5 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF1906 PF08924.11 KER27773.1 - 0.18 11.9 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) 7tm_1 PF00001.21 KER27774.1 - 9.1e-11 41.6 14.0 1.7e-10 40.7 14.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TCR PF03638.15 KER27775.1 - 7.2e-11 42.2 23.2 7.2e-11 42.2 23.2 1.9 2 0 0 2 2 2 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 KER27775.1 - 0.28 11.3 18.8 0.82 9.8 18.8 1.8 1 0 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 PAP2 PF01569.21 KER27776.1 - 0.0048 16.7 0.2 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily CTU2 PF10288.9 KER27777.1 - 3.1e-10 40.3 0.2 3.1e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KER27777.1 - 2.6e-07 30.6 0.0 4e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 PP-loop family zf-C2H2_3 PF13878.6 KER27777.1 - 0.48 10.3 0.1 0.48 10.3 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO HMG_box PF00505.19 KER27778.1 - 1.6e-21 76.5 1.4 2.9e-21 75.7 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER27778.1 - 4.9e-08 33.4 0.8 1.1e-07 32.3 0.8 1.5 1 0 0 1 1 1 1 HMG-box domain Cadherin PF00028.17 KER27781.1 - 6.5e-68 225.2 10.2 1e-11 45.1 0.0 8.3 8 2 0 8 8 8 7 Cadherin domain Cadherin_3 PF16184.5 KER27781.1 - 2e-08 34.2 4.5 0.24 11.4 0.0 5.6 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 KER27781.1 - 0.0022 17.8 5.1 7.7 6.4 3.1 5.8 5 1 0 5 5 5 1 Cadherin-like PQQ PF01011.21 KER27781.1 - 0.036 14.0 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat zf-C2H2 PF00096.26 KER27782.1 - 0.034 14.6 3.4 0.034 14.6 3.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Innexin PF00876.18 KER27784.1 - 4.6e-120 401.1 5.1 1.2e-118 396.4 5.1 2.1 1 1 0 1 1 1 1 Innexin RRM_1 PF00076.22 KER27786.1 - 1.6e-07 31.0 0.1 1.8e-05 24.5 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 KER27787.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OMP_b-brl PF13505.6 KER27788.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Choline_kinase PF01633.20 KER27790.1 - 1.3e-38 132.8 0.0 1.9e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 KER27790.1 - 1e-06 28.9 0.0 7.4e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 KER27790.1 - 0.022 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase NRIP1_repr_4 PF15690.5 KER27790.1 - 0.18 11.1 0.4 0.28 10.5 0.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 4 Rsbr_N PF08678.10 KER27791.1 - 0.069 13.2 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Rsbr N terminal IBR PF01485.21 KER27793.1 - 0.0053 16.9 5.4 0.0099 16.1 5.4 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Rav1p_C PF12234.8 KER27794.1 - 2.3e-53 181.6 0.0 8.3e-45 153.3 0.0 4.8 5 0 0 5 5 5 4 RAVE protein 1 C terminal WD40 PF00400.32 KER27794.1 - 6.4e-10 39.5 6.1 4e-05 24.3 0.0 5.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER27794.1 - 0.00031 21.0 0.0 0.029 14.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KER27796.1 - 0.0019 18.2 0.1 0.0051 16.8 0.1 1.7 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 KER27796.1 - 0.12 13.3 0.8 21 6.2 0.2 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Integrase_H2C2 PF17921.1 KER27797.1 - 1.3e-10 41.2 0.3 3.8e-10 39.7 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 KER27797.1 - 4.6e-07 29.6 0.0 9.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KER27797.1 - 1.5e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KER27797.1 - 0.071 13.3 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger MA-Mit PF09245.10 KER27798.1 - 0.12 11.9 0.4 0.21 11.0 0.4 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen 7tm_2 PF00002.24 KER27799.1 - 0.028 13.7 0.1 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) CUB PF00431.20 KER27801.1 - 4.2e-26 91.4 0.1 4.7e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 CUB domain RXT2_N PF08595.11 KER27802.1 - 0.025 14.6 6.3 0.028 14.4 6.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PTPRCAP PF15713.5 KER27802.1 - 0.027 14.8 3.5 0.033 14.5 3.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated eIF-3c_N PF05470.12 KER27802.1 - 0.065 11.6 2.7 0.054 11.8 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.13 KER27802.1 - 0.084 12.7 7.2 0.076 12.9 7.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 KER27802.1 - 0.1 11.9 19.3 0.1 11.9 19.3 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KER27802.1 - 0.12 11.9 8.7 0.12 12.0 8.7 1.1 1 0 0 1 1 1 0 PPP4R2 NPIP PF06409.11 KER27802.1 - 0.13 11.3 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) CDC45 PF02724.14 KER27802.1 - 0.19 10.0 9.6 0.18 10.1 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KER27802.1 - 0.19 10.2 8.5 0.17 10.4 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 KER27802.1 - 0.61 9.0 6.7 0.54 9.1 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ANAPC15 PF15243.6 KER27802.1 - 1 9.8 15.4 1.2 9.5 15.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DNA_pol_phi PF04931.13 KER27802.1 - 1.1 7.3 22.9 1.1 7.2 22.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Tom22 PF04281.13 KER27802.1 - 1.7 8.5 6.2 1.9 8.3 6.2 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.12 KER27802.1 - 1.7 6.7 13.1 1.7 6.7 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 KER27802.1 - 2 6.4 5.5 1.9 6.5 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Utp14 PF04615.13 KER27802.1 - 2.3 6.7 13.1 2.5 6.6 13.1 1.0 1 0 0 1 1 1 0 Utp14 protein Pes-10 PF07149.11 KER27802.1 - 2.5 7.1 11.9 2.6 7.0 11.9 1.1 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 KER27802.1 - 3.2 7.1 14.3 3.4 7.0 14.3 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER27802.1 - 4 6.7 10.5 3.9 6.7 10.5 1.0 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.11 KER27802.1 - 5.2 5.4 10.6 5.3 5.4 10.6 1.0 1 0 0 1 1 1 0 SGT1 protein EBV-NA3 PF05009.12 KER27802.1 - 5.3 6.5 5.1 5.2 6.5 5.1 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RNA_pol_3_Rpc31 PF11705.8 KER27802.1 - 9.3 6.4 19.0 10 6.3 19.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CBS PF00571.28 KER27803.1 - 9.2e-05 22.8 0.0 0.58 10.6 0.0 4.4 5 0 0 5 5 5 2 CBS domain RRM_1 PF00076.22 KER27805.1 - 2.1e-36 123.6 0.0 4.9e-17 61.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER27805.1 - 0.02 14.7 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 KER27807.1 - 1e-16 60.5 0.0 1.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER27807.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif SET_assoc PF11767.8 KER27807.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated FERM_M PF00373.18 KER27810.1 - 3.8e-11 43.4 0.0 8.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KER27810.1 - 3.3e-09 37.0 0.1 5.7e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SCVP PF17619.2 KER27810.1 - 0.094 13.6 0.0 0.21 12.5 0.0 1.5 1 0 0 1 1 1 0 Secreted clade V proteins DENN PF02141.21 KER27812.1 - 2e-36 125.7 0.9 3.8e-36 124.8 0.9 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KER27812.1 - 3.1e-09 37.4 1.2 1.6e-08 35.2 0.5 2.7 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 KER27812.1 - 5.5e-05 23.1 1.1 0.00013 21.9 1.1 1.7 1 0 0 1 1 1 1 dDENN domain Pkinase PF00069.25 KER27815.1 - 4.3e-51 173.8 0.0 1.1e-39 136.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER27815.1 - 3e-19 69.3 0.0 1.3e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KER27815.1 - 0.05 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KER27815.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rubredoxin_2 PF18073.1 KER27816.1 - 0.09 12.5 1.3 0.22 11.3 1.3 1.7 1 0 0 1 1 1 0 Rubredoxin metal binding domain Ldl_recept_a PF00057.18 KER27816.1 - 0.18 12.1 2.1 0.54 10.5 2.1 1.8 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A rve PF00665.26 KER27817.1 - 1.2e-16 61.0 0.0 1.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 KER27817.1 - 1.4e-15 57.1 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER27817.1 - 2.3e-10 40.7 0.0 3.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 KER27817.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain ELYS PF13934.6 KER27817.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore complex assembly PEHE PF15275.6 KER27818.1 - 7.5e-23 81.6 0.8 7.5e-23 81.6 0.8 4.2 5 0 0 5 5 5 1 PEHE domain Lysis_col PF02402.16 KER27818.1 - 0.33 10.7 1.3 0.88 9.3 1.3 1.7 1 0 0 1 1 1 0 Lysis protein Hormone_recep PF00104.30 KER27820.1 - 7.6e-16 58.3 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EF-hand_7 PF13499.6 KER27821.1 - 1.1e-24 86.6 5.6 5.3e-16 58.8 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KER27821.1 - 2.2e-24 83.1 6.7 1.6e-07 30.3 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER27821.1 - 3.1e-20 70.3 5.1 3.2e-05 23.5 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KER27821.1 - 1.6e-18 65.3 3.1 9.4e-05 21.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KER27821.1 - 9.2e-15 54.2 5.2 0.00022 21.0 0.2 3.9 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER27821.1 - 1.1e-05 25.7 2.3 0.013 15.8 0.5 3.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER27821.1 - 3.4e-05 23.7 1.0 0.067 13.1 0.0 3.5 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER27821.1 - 0.038 14.2 0.1 0.92 9.8 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 KER27821.1 - 0.16 11.9 4.9 4.2 7.3 0.1 3.5 3 1 0 4 4 4 0 Caleosin related protein Aa_trans PF01490.18 KER27823.1 - 1.1e-24 87.0 30.7 1.1e-24 87.0 30.7 2.3 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein DUF1036 PF06282.11 KER27823.1 - 0.0052 17.3 0.0 0.0091 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1036) Pkinase PF00069.25 KER27825.1 - 7.1e-68 228.8 0.0 8.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27825.1 - 3.7e-33 114.9 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER27825.1 - 0.039 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Guanylate_cyc PF00211.20 KER27826.1 - 1.9e-30 105.8 0.0 2.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SDF PF00375.18 KER27829.1 - 7.7e-128 426.8 25.3 9.2e-128 426.6 25.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family WD40 PF00400.32 KER27831.1 - 1.2e-19 70.2 10.7 0.00076 20.2 0.5 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KER27831.1 - 0.00092 18.0 3.2 0.96 8.0 0.1 3.3 3 1 0 3 3 3 3 Nucleoporin Nup120/160 NGP1NT PF08153.12 KER27832.1 - 1.8e-45 154.3 0.4 3.2e-45 153.5 0.4 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KER27832.1 - 1.9e-17 63.4 0.0 9.3e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KER27832.1 - 1.5e-05 24.6 0.0 3.6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KER27832.1 - 5.5e-05 23.1 0.0 0.00021 21.2 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KER27832.1 - 8.1e-05 22.7 0.1 1.1 9.3 0.0 3.4 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KER27832.1 - 0.0008 19.0 0.0 0.12 11.9 0.0 3.2 1 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KER27832.1 - 0.0036 16.8 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KER27832.1 - 0.049 13.9 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KER27832.1 - 0.064 13.6 0.7 3.8 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KER27832.1 - 0.12 12.9 0.0 0.38 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain TMA7 PF09072.10 KER27833.1 - 5.7e-21 75.1 21.3 6.2e-21 75.0 21.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 THOC7 PF05615.13 KER27833.1 - 0.066 13.5 5.6 0.071 13.4 5.6 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 DUF1759 PF03564.15 KER27834.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Viral_protease PF08715.10 KER27834.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Papain like viral protease Arfaptin PF06456.13 KER27835.1 - 3.4e-33 115.2 3.0 3.9e-33 114.9 3.0 1.0 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 KER27835.1 - 0.0022 17.7 0.7 0.0027 17.4 0.7 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KER27835.1 - 0.0057 15.8 1.7 0.0077 15.4 1.7 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-H2C2_2 PF13465.6 KER27837.1 - 3.5e-28 96.7 48.7 3e-06 27.4 1.2 8.9 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER27837.1 - 1.1e-24 85.0 60.1 0.0032 18.2 0.3 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KER27837.1 - 1.8e-24 84.7 58.3 0.0013 19.0 0.2 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-met PF12874.7 KER27837.1 - 2e-10 40.7 45.1 0.0085 16.4 1.9 8.7 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER27837.1 - 1.5e-08 34.8 52.1 0.0001 22.5 3.2 6.2 4 1 4 8 8 6 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KER27837.1 - 3.1e-06 27.1 46.6 0.02 14.9 0.2 8.5 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER27837.1 - 5.6e-06 26.5 50.4 0.0057 16.9 0.4 8.1 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KER27837.1 - 0.0003 21.0 4.0 2.4 8.5 0.1 5.0 4 0 0 4 4 4 1 zinc-ribbon Zn-C2H2_12 PF18112.1 KER27837.1 - 0.002 18.5 7.6 0.024 15.1 0.1 4.9 4 0 0 4 4 3 1 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 KER27837.1 - 0.011 15.8 24.4 3.3 7.9 0.1 5.4 4 2 0 4 4 4 0 Zinc ribbon domain CCDC53 PF10152.9 KER27837.1 - 0.012 16.0 17.5 0.026 15.0 5.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex zf-C2H2_3rep PF18868.1 KER27837.1 - 0.013 16.2 51.4 0.2 12.3 2.1 7.6 4 2 2 6 6 5 0 Zinc finger C2H2-type, 3 repeats Baculo_IE-1 PF05290.11 KER27837.1 - 0.094 12.7 17.3 3 7.8 0.1 4.3 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) Ctr PF04145.15 KER27837.1 - 0.63 10.6 7.4 4.7 7.8 0.8 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Suf PF05843.14 KER27837.1 - 0.67 9.9 34.5 0.94 9.4 3.5 2.5 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1677 PF07911.13 KER27837.1 - 0.84 10.1 0.0 0.84 10.1 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1677) zf-C2H2_8 PF15909.5 KER27837.1 - 1.3 9.3 25.4 0.54 10.6 1.1 3.7 2 1 2 4 4 4 0 C2H2-type zinc ribbon Presenilin PF01080.17 KER27837.1 - 1.5 7.5 15.9 0.18 10.5 4.7 2.2 2 0 0 2 2 2 0 Presenilin EPL1 PF10513.9 KER27837.1 - 1.6 9.1 16.2 0.26 11.6 4.3 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like PAT1 PF09770.9 KER27837.1 - 2.1 6.5 36.2 0.47 8.7 20.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spt46 PF17734.1 KER27837.1 - 3 7.6 22.8 0.18 11.6 0.6 5.0 2 1 2 5 5 5 0 Spermatogenesis-associated protein 46 RPA43_OB PF17875.1 KER27837.1 - 3.7 8.2 8.5 1.2 9.8 1.8 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Spt20 PF12090.8 KER27837.1 - 4.6 6.8 58.5 6.3 6.3 33.1 2.6 2 0 0 2 2 2 0 Spt20 family Arf PF00025.21 KER27838.1 - 4.1e-55 185.9 0.5 9.5e-55 184.7 0.5 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER27838.1 - 3.4e-09 36.4 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KER27838.1 - 4.9e-09 35.8 0.8 4.6e-05 22.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KER27838.1 - 5.1e-09 36.4 0.1 9.4e-09 35.5 0.1 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER27838.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KER27838.1 - 5.8e-07 29.1 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER27838.1 - 2.2e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KER27838.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Cyclin_C_2 PF16899.5 KER27838.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 Cyclin C-terminal domain LINES_N PF14694.6 KER27839.1 - 5.4e-05 22.8 3.9 0.0001 21.9 3.9 1.6 1 1 0 1 1 1 1 Lines N-terminus PDZ PF00595.24 KER27840.1 - 3.2e-05 24.2 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER27840.1 - 0.0039 17.0 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M15_3 PF08291.11 KER27842.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M15 HTH_Tnp_Tc5 PF03221.16 KER27844.1 - 2e-10 40.6 0.0 4.5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Kdo PF06293.14 KER27844.1 - 5.7e-08 32.4 0.1 2e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER27844.1 - 6.9e-07 29.4 3.3 0.00011 22.2 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KER27844.1 - 2e-06 27.4 1.2 4.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27844.1 - 0.00056 19.3 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ATG16 PF08614.11 KER27844.1 - 0.018 15.3 35.7 0.13 12.5 13.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RIO1 PF01163.22 KER27844.1 - 0.026 14.1 0.8 0.47 10.0 0.0 2.7 3 0 0 3 3 3 0 RIO1 family MAD PF05557.13 KER27844.1 - 0.027 12.9 30.6 0.22 9.8 19.4 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein HALZ PF02183.18 KER27844.1 - 0.038 14.2 20.7 0.88 9.9 0.2 5.6 4 1 2 6 6 6 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 KER27844.1 - 0.12 12.4 32.0 0.083 13.0 22.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KER27844.1 - 0.37 11.2 29.5 0.68 10.3 29.5 1.4 1 0 0 1 1 1 0 Fez1 Cep57_CLD_2 PF14197.6 KER27844.1 - 0.5 10.5 29.1 0.49 10.5 2.7 4.0 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 KER27844.1 - 0.68 10.5 33.7 0.54 10.8 9.4 2.8 1 1 1 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 KER27844.1 - 1.3 8.4 32.3 1.5 8.1 16.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KER27844.1 - 1.4 7.7 28.0 3 6.6 27.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KER27844.1 - 1.6 8.5 32.6 7.5 6.3 32.1 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-C4H2 PF10146.9 KER27844.1 - 2.3 8.5 22.0 2.1e+02 2.1 22.1 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein FlaC_arch PF05377.11 KER27844.1 - 2.9 8.4 10.6 0.42 11.0 0.7 3.5 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.11 KER27844.1 - 2.9 7.7 11.8 3 7.6 2.0 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CorA PF01544.18 KER27844.1 - 3.7 6.8 14.0 24 4.1 13.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4600 PF15372.6 KER27844.1 - 4 7.9 24.5 8.6 6.8 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TSC22 PF01166.18 KER27844.1 - 5 7.5 19.1 0.4 11.0 0.8 4.2 2 1 1 4 4 4 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 KER27844.1 - 5.6 7.0 33.0 36 4.4 21.9 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HELP PF03451.14 KER27846.1 - 2.1e-25 88.4 0.1 4.4e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 KER27846.1 - 2.8e-25 88.1 27.4 0.00025 21.8 0.1 9.6 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER27846.1 - 4.6e-08 33.3 0.0 0.0013 19.0 0.0 4.4 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER27846.1 - 0.13 11.6 0.0 9.4 5.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like domain RVT_1 PF00078.27 KER27847.1 - 5.1e-05 22.9 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_3 PF16017.5 KER27847.1 - 0.16 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Tim17 PF02466.19 KER27849.1 - 0.066 13.6 0.0 0.072 13.5 0.0 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 KER27851.1 - 1.1e-82 277.4 0.0 7.8e-68 228.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER27851.1 - 1.8e-44 152.0 0.0 1.9e-35 122.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER27851.1 - 1.4e-07 31.2 0.2 5.7e-07 29.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KER27851.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L27e PF01777.18 KER27851.1 - 0.1 12.9 0.3 0.31 11.4 0.3 1.8 1 0 0 1 1 1 0 Ribosomal L27e protein family IFT20 PF14931.6 KER27851.1 - 0.83 9.8 5.1 2 8.6 5.1 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 KCNQ2_u3 PF16642.5 KER27851.1 - 4 8.5 7.7 0.8 10.7 0.9 3.4 2 1 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 CytochromB561_N PF09786.9 KER27852.1 - 0.0031 16.6 3.5 0.0037 16.3 3.5 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF3283 PF11686.8 KER27852.1 - 0.051 13.4 2.7 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) RhoGEF67_u2 PF16614.5 KER27852.1 - 0.21 11.7 3.2 6.3 6.9 0.3 2.2 1 1 1 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 DUF3314 PF11771.8 KER27852.1 - 0.92 9.6 8.0 4.1 7.5 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3314) Baculo_LEF-3 PF05847.11 KER27852.1 - 1.9 7.6 8.7 5.7 6.0 2.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) DUF3474 PF11960.8 KER27852.1 - 8.6 6.6 9.7 12 6.1 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) Exo_endo_phos_2 PF14529.6 KER27853.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MMR_HSR1_Xtn PF16897.5 KER27855.1 - 3.5e-43 145.9 0.2 7.4e-43 144.9 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KER27855.1 - 1.5e-23 82.6 0.0 2.8e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KER27855.1 - 1.4e-18 67.0 0.0 4.1e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase COX6B PF02297.17 KER27855.1 - 1.7e-13 50.6 7.4 2.9e-13 49.8 7.4 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb FeoB_N PF02421.18 KER27855.1 - 6.5e-10 38.8 0.0 4.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KER27855.1 - 0.0076 16.3 0.1 2 8.4 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KER27855.1 - 0.013 15.0 0.1 0.49 9.9 0.0 3.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 KER27855.1 - 0.036 13.0 0.1 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1041 PF06292.17 KER27857.1 - 1.9e-30 105.4 0.1 6.3e-30 103.7 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) RVT_1 PF00078.27 KER27857.1 - 3e-11 43.3 0.0 7.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.29 KER27857.1 - 1.7e-06 28.5 0.0 4.9e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 PH domain UQ_con PF00179.26 KER27859.1 - 9.9e-26 90.1 0.0 2.3e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KER27859.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 UEV domain BTP PF05232.12 KER27859.1 - 0.14 12.3 0.9 0.38 10.9 0.9 1.8 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Pkinase_Tyr PF07714.17 KER27862.1 - 8.8e-76 254.6 0.0 3.2e-63 213.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER27862.1 - 7.1e-32 110.8 0.0 1.2e-28 100.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Recep_L_domain PF01030.24 KER27862.1 - 7.1e-27 93.8 0.0 8.8e-19 67.7 0.0 2.6 2 0 0 2 2 2 2 Receptor L domain Furin-like PF00757.20 KER27862.1 - 4.7e-22 78.5 32.3 2.2e-21 76.3 32.3 2.2 1 1 0 1 1 1 1 Furin-like cysteine rich region fn3 PF00041.21 KER27862.1 - 1.3e-05 25.4 8.3 0.33 11.3 0.2 5.1 5 0 0 5 5 5 2 Fibronectin type III domain Kinase-like PF14531.6 KER27862.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GF_recep_IV PF14843.6 KER27862.1 - 2.6 7.8 36.0 0.014 15.2 20.9 3.6 1 1 2 3 3 3 0 Growth factor receptor domain IV Mito_carr PF00153.27 KER27865.1 - 2e-37 127.0 0.1 4.4e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_1 PF08018.11 KER27866.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide Pou PF00157.17 KER27867.1 - 2.2e-29 101.2 0.0 5.9e-29 99.9 0.0 1.8 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KER27867.1 - 4e-16 58.6 1.6 1.1e-15 57.2 1.6 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KER27867.1 - 0.002 18.5 0.0 0.006 16.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KER27867.1 - 0.056 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Ank_5 PF13857.6 KER27868.1 - 0.036 14.4 0.5 6 7.3 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF3699 PF12480.8 KER27869.1 - 0.054 13.7 0.1 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) gag-asp_proteas PF13975.6 KER27870.1 - 2e-06 28.3 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER27870.1 - 5.2e-06 27.0 0.0 9.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KER27870.1 - 0.0026 17.6 0.0 0.0062 16.3 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER27870.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 KER27870.1 - 0.11 12.2 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease ArfGap PF01412.18 KER27871.1 - 2e-32 111.7 0.2 5.6e-32 110.3 0.2 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KER27871.1 - 3.2e-14 53.3 0.1 4.2e-06 27.2 0.0 3.2 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 KER27871.1 - 1.5e-13 51.1 0.2 9.2e-11 42.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) BAR_3 PF16746.5 KER27871.1 - 6.7e-11 42.3 0.0 1.9e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 BAR domain of APPL family Ank_4 PF13637.6 KER27871.1 - 1.1e-10 41.8 0.9 7.6e-09 35.9 0.6 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER27871.1 - 2.3e-10 39.8 0.1 0.0012 19.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KER27871.1 - 1.5e-08 34.7 1.0 0.0002 21.6 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KER27871.1 - 1.7e-07 31.3 2.7 0.0089 16.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 KER27871.1 - 0.042 14.3 3.7 0.22 11.9 1.3 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Aminotran_3 PF00202.21 KER27872.1 - 2.1e-105 352.7 0.0 2.4e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KER27872.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II Nup35_RRM PF05172.13 KER27874.1 - 6.6e-21 74.2 0.1 2.8e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KER27874.1 - 3.7e-09 36.4 0.0 7.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR_2 PF13233.6 KER27874.1 - 0.0017 19.0 0.2 0.0031 18.2 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Acyl-CoA_dh_1 PF00441.24 KER27875.1 - 2.8e-46 157.4 1.3 4.3e-46 156.8 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KER27875.1 - 1.8e-26 93.0 0.0 1.2e-25 90.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KER27875.1 - 9.2e-26 90.7 0.2 1.3e-25 90.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KER27875.1 - 1.3e-24 86.2 0.0 2.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KER27875.1 - 0.018 15.6 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PDZ PF00595.24 KER27876.1 - 2.4e-07 31.0 0.1 8e-07 29.3 0.0 1.7 1 1 1 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KER27876.1 - 6.5e-07 29.1 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER27876.1 - 9.8e-07 29.0 0.1 2.8e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 PDZ domain Plasmid_stab_B PF10784.9 KER27876.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein RVT_1 PF00078.27 KER27877.1 - 1.3e-18 67.4 0.0 4.4e-10 39.4 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.28 KER27879.1 - 3.2e-17 63.4 0.6 3.9e-16 59.9 0.0 2.7 2 2 0 2 2 2 1 SET domain DUF2956 PF11169.8 KER27879.1 - 0.018 15.2 4.1 0.018 15.2 4.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2956) EF-hand_7 PF13499.6 KER27880.1 - 3e-19 69.2 2.4 2.5e-10 40.7 0.3 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KER27880.1 - 1.1e-18 65.4 2.3 6.5e-06 25.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KER27880.1 - 6.4e-16 56.9 3.4 0.0001 21.9 0.2 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KER27880.1 - 3.4e-11 42.1 2.4 0.00061 19.2 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KER27880.1 - 4e-09 36.2 5.9 6.7e-05 22.7 0.3 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KER27880.1 - 0.027 14.4 0.8 7 6.7 0.0 3.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER27880.1 - 0.065 13.6 1.0 2 8.8 0.2 3.2 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER27880.1 - 0.076 13.3 0.0 16 5.9 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Cytochrom_B561 PF03188.16 KER27884.1 - 2e-43 147.8 8.0 2.8e-43 147.4 8.0 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KER27884.1 - 2.3 8.4 12.6 35 4.5 12.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) polyprenyl_synt PF00348.17 KER27885.1 - 1.6e-33 115.9 0.0 2.1e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MH2 PF03166.14 KER27887.1 - 7.6e-22 78.4 0.1 1.8e-18 67.5 0.0 2.3 2 0 0 2 2 2 2 MH2 domain MH1 PF03165.16 KER27887.1 - 4.6e-11 42.9 1.3 1.1e-10 41.6 1.3 1.7 1 0 0 1 1 1 1 MH1 domain NYD-SP28 PF14772.6 KER27890.1 - 3e-23 81.8 11.3 3e-23 81.8 11.3 5.1 5 2 1 6 6 6 2 Sperm tail NYD-SP28_assoc PF14775.6 KER27890.1 - 9e-05 22.5 0.8 9e-05 22.5 0.8 5.1 4 1 0 4 4 4 1 Sperm tail C-terminal domain Lectin_N PF03954.14 KER27890.1 - 1.9 8.2 27.3 0.48 10.2 2.4 4.6 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain FUSC PF04632.12 KER27890.1 - 4.8 5.6 10.6 2.2 6.7 1.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family EDS1_EP PF18117.1 KER27890.1 - 8.5 6.9 12.6 2.2 8.8 2.2 3.5 3 0 0 3 3 3 0 Enhanced disease susceptibility 1 protein EP domain S100PBPR PF15427.6 KER27891.1 - 0.082 12.2 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 S100P-binding protein POP1 PF06978.11 KER27892.1 - 1.8e-28 99.9 13.4 3e-17 63.3 0.1 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KER27892.1 - 1.9e-10 40.9 1.2 0.075 13.4 0.1 5.5 4 1 0 4 4 4 3 POPLD (NUC188) domain Fer4_19 PF06902.11 KER27892.1 - 0.0098 16.0 0.2 7.6 6.7 0.0 2.7 2 0 0 2 2 2 2 Divergent 4Fe-4S mono-cluster KKLCAg1 PF15204.6 KER27892.1 - 0.044 13.9 1.7 10 6.3 0.2 2.4 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Noelin-1 PF12308.8 KER27892.1 - 0.17 11.9 0.2 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein HECT PF00632.25 KER27893.1 - 8.6e-90 301.3 0.0 1.3e-89 300.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KER27893.1 - 8.6e-20 70.7 5.4 1.9e-19 69.6 5.4 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Exo_endo_phos_2 PF14529.6 KER27894.1 - 3.4e-09 36.6 0.0 0.003 17.4 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase DUF5568 PF17724.1 KER27894.1 - 0.037 13.8 0.0 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5568) DUF3747 PF12565.8 KER27894.1 - 0.044 13.1 0.0 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) JmjC PF02373.22 KER27895.1 - 6.2e-43 145.8 0.2 1.6e-42 144.6 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KER27895.1 - 1.9e-28 98.1 35.0 1.3e-10 41.0 5.0 4.0 3 0 0 3 3 3 3 PHD-finger PLU-1 PF08429.11 KER27895.1 - 3.9e-16 59.2 0.1 7.8e-14 51.6 0.0 3.9 3 1 0 3 3 3 1 PLU-1-like protein ARID PF01388.21 KER27895.1 - 1.3e-14 54.6 0.0 3.3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KER27895.1 - 3.9e-12 45.9 0.5 9.2e-12 44.7 0.5 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KER27895.1 - 1.3e-11 44.7 11.1 1.3e-11 44.7 11.1 3.1 3 0 0 3 3 3 1 C5HC2 zinc finger TIR_2 PF13676.6 KER27897.1 - 5.2e-13 49.6 0.0 1.8e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 TIR domain SAM_1 PF00536.30 KER27897.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 KER27897.1 - 0.031 14.1 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1127 PF06568.11 KER27897.1 - 0.089 12.5 0.3 0.32 10.8 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Ank_2 PF12796.7 KER27899.1 - 1.1e-32 112.5 1.3 5.3e-16 59.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KER27899.1 - 1.1e-30 104.7 3.1 7.1e-05 23.1 0.7 6.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KER27899.1 - 9.2e-28 96.0 5.5 4.9e-09 36.3 0.0 5.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER27899.1 - 1.6e-26 92.3 0.2 1.9e-07 31.5 0.2 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER27899.1 - 1.2e-24 83.7 1.8 1.3e-05 25.2 0.2 6.6 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 KER27900.1 - 4.3e-20 72.2 17.8 4.3e-20 72.2 17.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KER27900.1 - 1.5e-14 54.3 1.3 1.9e-12 47.6 0.5 3.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER27900.1 - 5.5e-14 52.3 1.3 1.2e-08 35.3 0.6 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER27900.1 - 2.8e-13 49.8 2.2 1.4e-05 25.3 0.7 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER27900.1 - 5.9e-13 47.7 0.2 0.00019 21.6 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KER27900.1 - 7.8e-13 48.2 7.1 8.3e-08 32.4 0.3 4.4 5 0 0 5 5 5 3 Ankyrin repeat DctQ PF04290.12 KER27900.1 - 2.1 8.3 8.2 0.1 12.5 0.8 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component TBP PF00352.21 KER27902.1 - 3.5e-68 225.6 0.6 4.3e-33 113.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KER27902.1 - 9.1e-05 22.5 0.3 0.55 10.4 0.0 3.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3378) Fasciclin PF02469.22 KER27903.1 - 5.4e-28 97.8 0.0 8e-14 52.0 0.0 5.0 5 0 0 5 5 5 3 Fasciclin domain MTCP1 PF08991.10 KER27903.1 - 0.2 11.9 3.1 0.6 10.4 1.9 2.4 1 1 1 2 2 2 0 Mature-T-Cell Proliferation I type AAA_6 PF12774.7 KER27904.1 - 2e-155 516.7 0.0 3e-153 509.6 0.0 3.4 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 KER27904.1 - 1.3e-137 458.5 8.7 2.5e-137 457.5 8.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 KER27904.1 - 3.3e-131 438.7 7.5 3.3e-131 438.7 7.5 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KER27904.1 - 2.1e-107 359.7 15.1 2.1e-107 359.7 15.1 3.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KER27904.1 - 5.7e-93 311.0 0.0 3e-92 308.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER27904.1 - 5e-82 274.3 0.4 5e-82 274.3 0.4 2.8 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER27904.1 - 1.5e-74 249.5 0.1 4.6e-67 225.0 0.0 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 KER27904.1 - 3.7e-38 130.3 0.0 3.6e-37 127.1 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 KER27904.1 - 4.1e-31 107.1 2.2 1.2e-30 105.6 0.1 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KER27904.1 - 5.6e-26 91.2 0.0 9e-12 45.2 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KER27904.1 - 1.1e-25 90.2 1.3 9.5e-25 87.2 1.3 2.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 KER27904.1 - 5e-07 30.3 0.1 0.53 10.7 0.0 5.9 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KER27904.1 - 2.1e-06 28.1 0.0 2 8.7 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 KER27904.1 - 7.7e-05 22.5 0.7 1 9.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KER27904.1 - 0.0002 21.9 0.7 0.51 10.9 0.0 5.1 5 0 0 5 5 3 1 AAA domain Sigma54_activat PF00158.26 KER27904.1 - 0.00026 20.7 0.0 0.047 13.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KER27904.1 - 0.0018 18.7 0.1 0.67 10.4 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KER27904.1 - 0.0038 16.5 0.0 1.5 7.9 0.0 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KER27904.1 - 0.0042 17.5 0.6 37 4.8 0.0 4.3 4 0 0 4 4 3 0 RNA helicase AAA_14 PF13173.6 KER27904.1 - 0.0062 16.6 0.0 16 5.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 KER27904.1 - 0.011 15.5 0.9 1.5 8.5 0.0 4.2 5 0 0 5 5 5 0 AAA domain Mg_chelatase PF01078.21 KER27904.1 - 0.018 14.4 0.1 4.8 6.5 0.0 3.4 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KER27904.1 - 0.025 13.7 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase AAA_19 PF13245.6 KER27904.1 - 0.032 14.6 2.1 29 5.0 0.0 4.4 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.9 KER27904.1 - 0.032 13.1 2.7 0.25 10.2 0.0 3.3 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KER27904.1 - 0.033 13.4 0.2 9.8 5.3 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KER27904.1 - 0.036 13.8 1.0 0.46 10.2 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activ_2 PF14532.6 KER27904.1 - 0.039 14.1 0.0 9.7 6.3 0.0 3.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 KER27904.1 - 0.072 12.9 0.3 45 3.9 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KER27904.1 - 0.11 12.6 0.2 1.1e+02 2.9 0.0 4.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KER27904.1 - 0.14 12.3 0.1 14 5.9 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KER27904.1 - 0.17 11.5 0.3 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KER27904.1 - 0.17 12.1 0.7 1.9e+02 2.2 0.0 4.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KER27904.1 - 1.1 9.7 9.5 10 6.6 0.0 4.8 6 0 0 6 6 2 0 ABC transporter PHM7_cyt PF14703.6 KER27904.1 - 2.1 8.5 5.1 2.3 8.4 0.2 3.5 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4543 PF15076.6 KER27906.1 - 0.0019 18.3 0.1 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4543) DUF5053 PF16476.5 KER27906.1 - 0.002 17.7 0.2 2 8.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5053) SAC3_GANP PF03399.16 KER27907.1 - 4e-15 56.0 0.6 4.1e-13 49.4 0.0 2.8 3 1 0 3 3 3 1 SAC3/GANP family ParD PF09386.10 KER27907.1 - 0.095 13.1 0.6 0.95 9.9 0.1 2.4 2 0 0 2 2 2 0 Antitoxin ParD DUF1687 PF07955.11 KER27907.1 - 0.58 10.6 4.8 2.3 8.7 3.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1687) C2 PF00168.30 KER27908.1 - 3e-34 117.4 0.0 2e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain Syndecan PF01034.20 KER27908.1 - 0.019 14.8 1.6 0.043 13.7 1.6 1.5 1 0 0 1 1 1 0 Syndecan domain CEP76-C2 PF15627.6 KER27908.1 - 0.045 13.3 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 CEP76 C2 domain MscL PF01741.18 KER27908.1 - 0.07 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Glycophorin_A PF01102.18 KER27908.1 - 0.078 13.2 0.1 0.3 11.3 0.0 1.9 2 1 0 2 2 2 0 Glycophorin A DUF2207 PF09972.9 KER27908.1 - 0.1 11.3 0.0 0.21 10.3 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4778 PF16008.5 KER27910.1 - 0.23 11.5 2.3 0.29 11.2 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) NAM-associated PF14303.6 KER27910.1 - 2.5 8.8 5.1 1.6 9.4 0.7 2.1 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain AIG2_2 PF13772.6 KER27912.1 - 3.9e-18 65.6 0.0 6.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KER27912.1 - 2.2e-05 25.1 0.0 3.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like TyrRSs_C PF16714.5 KER27914.1 - 0.064 13.1 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DUF2656 PF10847.8 KER27914.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) DHC_N1 PF08385.12 KER27915.1 - 1e-106 357.9 4.3 2.2e-75 254.4 4.3 3.5 2 2 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KER27915.1 - 2.5e-98 329.8 2.0 2.5e-98 329.8 2.0 4.3 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 UPF0254 PF06787.11 KER27915.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) ApoLp-III PF07464.11 KER27915.1 - 1.2 9.2 8.5 5.7 7.0 0.1 4.2 5 0 0 5 5 5 0 Apolipophorin-III precursor (apoLp-III) AAA_6 PF12774.7 KER27916.1 - 1e-151 504.5 0.1 2.4e-127 424.4 0.0 3.7 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 KER27916.1 - 5.1e-78 262.4 1.1 8.7e-69 232.1 0.1 3.2 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KER27916.1 - 3.3e-67 225.5 1.9 2.8e-58 196.4 0.0 5.7 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_8 PF12780.7 KER27916.1 - 1.6e-66 224.3 0.0 8e-66 222.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER27916.1 - 1.7e-66 223.5 2.5 1.2e-65 220.7 0.6 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 KER27916.1 - 9.3e-48 162.1 1.8 2.6e-47 160.7 1.8 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER27916.1 - 1.4e-39 136.1 0.3 2.2e-39 135.5 0.3 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER27916.1 - 1.7e-37 128.1 0.7 3.3e-33 114.3 0.0 4.3 3 1 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KER27916.1 - 1.9e-25 89.5 3.1 4.9e-08 33.1 0.0 6.7 7 1 0 7 7 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KER27916.1 - 6.3e-17 61.9 0.0 2.2e-16 60.1 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KER27916.1 - 1.1e-14 55.0 1.0 0.015 15.7 0.0 6.2 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_lid_1 PF17857.1 KER27916.1 - 4.6e-14 52.4 0.4 2.8e-13 49.9 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KER27916.1 - 5.7e-12 46.3 6.4 0.0074 16.7 0.1 6.9 6 1 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 KER27916.1 - 1.2e-11 45.0 13.8 0.00094 19.5 0.0 7.9 7 1 0 7 7 6 2 AAA domain AAA_30 PF13604.6 KER27916.1 - 1.9e-08 34.2 3.5 1.4 8.6 0.0 5.6 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 KER27916.1 - 2.7e-05 24.4 5.0 1.4 9.1 0.0 5.5 6 0 0 6 6 5 1 AAA domain Sigma54_activat PF00158.26 KER27916.1 - 5.8e-05 22.9 0.0 4.7 6.9 0.0 3.7 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.6 KER27916.1 - 0.0002 21.1 0.2 13 5.6 0.0 4.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KER27916.1 - 0.0012 19.3 0.2 22 5.5 0.0 4.2 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 KER27916.1 - 0.003 17.3 4.2 29 4.3 0.0 5.2 5 0 0 5 5 5 0 AAA domain AAA_19 PF13245.6 KER27916.1 - 0.0033 17.8 10.0 14 6.0 0.0 5.9 6 0 0 6 6 5 0 AAA domain Roc PF08477.13 KER27916.1 - 0.0038 17.4 0.5 1.1 9.5 0.0 3.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KER27916.1 - 0.0039 17.6 4.0 21 5.5 0.0 5.6 6 0 0 6 6 5 0 RNA helicase DUF815 PF05673.13 KER27916.1 - 0.0052 16.0 1.8 1.9 7.6 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Bac_DNA_binding PF00216.21 KER27916.1 - 0.0079 16.4 0.1 12 6.1 0.0 3.3 3 0 0 3 3 2 0 Bacterial DNA-binding protein Mg_chelatase PF01078.21 KER27916.1 - 0.014 14.7 1.5 20 4.5 0.0 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KER27916.1 - 0.017 15.1 5.5 0.66 10.0 0.0 4.7 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DHC_N2 PF08393.13 KER27916.1 - 0.037 13.1 0.0 0.037 13.1 0.0 3.3 5 0 0 5 5 5 0 Dynein heavy chain, N-terminal region 2 NACHT PF05729.12 KER27916.1 - 0.042 13.8 2.4 3.1 7.7 0.0 4.3 4 0 0 4 4 3 0 NACHT domain DUF853 PF05872.12 KER27916.1 - 0.083 11.5 3.1 0.44 9.1 0.0 3.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 KER27916.1 - 0.089 13.3 6.2 44 4.6 0.0 6.1 7 0 0 7 7 6 0 AAA domain MobB PF03205.14 KER27916.1 - 0.09 12.7 0.2 15 5.5 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 KER27916.1 - 0.11 11.9 4.7 4.1 6.7 0.0 3.7 4 0 0 4 4 3 0 FtsK/SpoIIIE family DUF1104 PF06518.11 KER27916.1 - 0.29 11.5 3.7 25 5.3 0.2 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1104) TrwB_AAD_bind PF10412.9 KER27916.1 - 0.42 9.5 4.3 7.4 5.4 0.1 3.6 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF3584 PF12128.8 KER27916.1 - 0.66 7.4 16.9 2.2 5.7 4.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF4200 PF13863.6 KER27916.1 - 1.3 9.5 9.1 2.8 8.4 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Pkinase PF00069.25 KER27918.1 - 2.8e-30 105.6 0.0 4.1e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER27918.1 - 1.2e-17 64.1 0.0 1.7e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 KER27919.1 - 8.6e-14 51.1 0.0 1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 KER27919.1 - 5.4 6.1 15.5 7.9 5.6 15.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tankyrase_bdg_C PF15327.6 KER27920.1 - 0.0011 19.4 1.4 0.002 18.6 1.2 1.4 1 1 0 1 1 1 1 Tankyrase binding protein C terminal domain GDA1_CD39 PF01150.17 KER27924.1 - 5.2e-90 302.1 0.0 8.1e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family fn3 PF00041.21 KER27926.1 - 8.9e-28 96.5 7.6 1.3e-07 31.8 0.5 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER27926.1 - 7.9e-05 23.2 4.8 1.8 9.2 1.2 4.6 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Il13Ra_Ig PF18001.1 KER27926.1 - 0.01 15.9 0.6 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain fn3_2 PF16893.5 KER27926.1 - 0.021 15.0 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 0 Fibronectin type III domain DUF2369 PF10179.9 KER27926.1 - 0.092 13.1 0.8 2.4 8.6 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 KER27926.1 - 0.095 13.2 0.5 2.4 8.8 0.1 2.9 3 1 0 3 3 3 0 PhoD-like phosphatase, N-terminal domain DUF2749 PF10907.8 KER27927.1 - 0.018 15.2 1.7 6.5 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) TMEM237 PF15383.6 KER27927.1 - 1.5 7.8 4.3 9.6 5.2 0.4 2.6 3 0 0 3 3 3 0 Transmembrane protein 237 AIM3 PF17096.5 KER27927.1 - 4.3 8.4 6.2 9.5 7.2 1.6 2.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 AATF-Che1 PF13339.6 KER27927.1 - 7.5 7.2 13.0 1.7e+02 2.9 13.0 2.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1664 PF07889.12 KER27927.1 - 8.6 6.4 9.4 7.1 6.7 6.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ion_trans PF00520.31 KER27930.1 - 0.00014 21.2 1.6 0.00014 21.2 1.6 1.8 2 0 0 2 2 2 1 Ion transport protein Nop14 PF04147.12 KER27935.1 - 0.43 8.7 27.7 0.42 8.8 27.7 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 KER27935.1 - 1.9 8.9 3.8 2.1 8.8 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 KER27935.1 - 4.1 5.6 21.6 4.2 5.5 21.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KER27935.1 - 6.6 4.7 43.8 6.9 4.6 43.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi TRP_2 PF08344.11 KER27936.1 - 2.6e-27 94.8 1.5 4.4e-27 94.1 1.5 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_3 PF13606.6 KER27936.1 - 1e-10 40.9 1.8 0.0068 16.8 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KER27936.1 - 4.5e-10 40.0 1.1 2.7e-06 27.9 0.3 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER27936.1 - 1.1e-07 32.2 0.5 0.028 15.0 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER27936.1 - 1.5e-06 28.3 0.8 0.17 12.3 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KER27936.1 - 1.8e-05 25.0 1.3 0.66 10.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat XPC-binding PF09280.11 KER27936.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 XPC-binding domain Asp PF00026.23 KER27937.1 - 3.9e-16 59.3 0.0 4.6e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Rad17 PF03215.15 KER27938.1 - 3.4e-18 66.2 0.0 6.3e-16 58.8 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 KER27938.1 - 2.1e-05 25.1 0.0 0.00021 21.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KER27938.1 - 3.3e-05 24.3 0.0 7.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KER27938.1 - 0.00045 20.5 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KER27938.1 - 0.0008 19.4 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KER27938.1 - 0.0037 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KER27938.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KER27938.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KER27938.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 KER27938.1 - 0.022 15.1 0.1 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KER27938.1 - 0.037 14.0 0.1 0.23 11.5 0.0 2.4 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KER27938.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KER27938.1 - 0.051 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KER27938.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_assoc_2 PF16193.5 KER27938.1 - 0.083 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain RsgA_GTPase PF03193.16 KER27938.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KER27938.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 KER27938.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KER27938.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KER27938.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KER27938.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KER27938.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KER27938.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KER27938.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KER27938.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase zf-RING_9 PF13901.6 KER27939.1 - 8.5e-28 97.7 16.4 1.4e-26 93.8 2.9 2.3 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon Prok-RING_2 PF14445.6 KER27939.1 - 0.0021 18.2 0.3 0.0021 18.2 0.3 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 C1_1 PF00130.22 KER27939.1 - 0.012 15.5 8.9 0.012 15.5 8.9 3.6 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VEK-30 PF12107.8 KER27940.1 - 0.17 11.8 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Inhibitor_I67 PF11405.8 KER27942.1 - 8.9 6.7 10.1 1.1 9.6 0.5 3.3 3 0 0 3 3 3 0 Bromelain inhibitor VI TPR_1 PF00515.28 KER27944.1 - 1.4e-24 84.8 17.7 6e-05 22.7 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KER27944.1 - 9.1e-24 81.6 16.1 0.014 15.4 0.0 9.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 KER27944.1 - 1.6e-20 71.5 10.7 0.023 14.9 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC8 PF04049.13 KER27944.1 - 1.3e-14 54.4 0.0 3.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 KER27944.1 - 7.5e-14 51.2 16.5 0.081 13.8 0.0 8.7 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KER27944.1 - 4.5e-11 43.2 17.2 0.00017 22.2 0.3 6.7 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER27944.1 - 4.8e-09 36.4 19.7 0.014 15.7 3.3 7.0 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER27944.1 - 1.1e-08 34.8 3.2 1.4 9.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER27944.1 - 2.8e-08 33.2 12.6 0.6 10.3 0.2 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER27944.1 - 3.3e-08 33.9 10.0 0.23 12.0 0.1 6.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KER27944.1 - 1.2e-06 28.1 9.5 0.0039 16.8 0.2 5.0 4 1 1 5 5 5 2 TPR repeat TPR_15 PF13429.6 KER27944.1 - 1.2e-06 28.0 2.6 6.8e-06 25.5 0.1 2.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER27944.1 - 5.2e-05 23.6 15.7 3.5 8.4 0.5 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER27944.1 - 0.0003 20.5 4.7 11 6.0 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KER27944.1 - 0.086 13.0 6.2 13 6.0 0.1 4.6 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KER27944.1 - 0.12 11.8 5.5 0.61 9.4 4.7 2.5 2 1 0 2 2 2 0 MalT-like TPR region Cdc6_C PF09079.11 KER27944.1 - 0.21 11.6 0.9 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain RPN7 PF10602.9 KER27944.1 - 0.32 10.7 4.8 44 3.7 2.9 3.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 SNAP PF14938.6 KER27944.1 - 0.46 9.8 8.1 0.55 9.6 3.3 3.1 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP eIF2A PF08662.11 KER27947.1 - 1.6e-30 106.4 0.8 1.3e-27 97.0 0.0 3.5 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KER27947.1 - 2.8e-09 37.1 0.2 2.1 8.7 0.0 6.3 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KER27947.1 - 8.1e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KER27947.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KER27947.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TagA PF12561.8 KER27947.1 - 0.064 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain YCII PF03795.14 KER27947.1 - 0.1 13.0 0.1 5.6 7.4 0.0 3.3 3 0 0 3 3 3 0 YCII-related domain DUF5315 PF17242.2 KER27948.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Ank_2 PF12796.7 KER27950.1 - 1.2e-28 99.6 2.4 5.3e-15 55.8 0.3 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER27950.1 - 6.3e-25 86.9 7.7 3.3e-08 33.7 1.3 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER27950.1 - 5.6e-24 84.2 5.2 8.5e-10 39.0 0.2 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KER27950.1 - 8.4e-22 76.6 10.2 4.2e-06 27.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KER27950.1 - 5.5e-18 63.2 9.3 7e-05 22.9 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF4817 PF16087.5 KER27953.1 - 4.4e-09 36.0 0.0 8.6e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) DDE_3 PF13358.6 KER27953.1 - 5e-06 26.3 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 KER27953.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 KER27953.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_Crp_2 PF13545.6 KER27953.1 - 0.015 15.2 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KER27953.1 - 0.017 15.0 0.1 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 MarR family HTH_24 PF13412.6 KER27953.1 - 0.059 12.9 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KER27953.1 - 0.081 12.7 0.0 0.34 10.8 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KER27953.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Mac PF12464.8 KER27953.1 - 0.16 12.2 0.1 22 5.4 0.0 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase SLAIN PF15301.6 KER27955.1 - 3.5e-06 26.6 5.9 0.00099 18.5 0.1 3.0 3 1 0 3 3 3 2 SLAIN motif-containing family Aldedh PF00171.22 KER27957.1 - 2.4e-104 349.4 0.0 3.2e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CCD PF07860.11 KER27958.1 - 0.018 15.1 0.4 0.18 11.9 0.2 2.4 2 0 0 2 2 2 0 WisP family C-Terminal Region DUF3218 PF11508.8 KER27959.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) zf-C2H2_4 PF13894.6 KER27961.1 - 0.0059 17.4 71.1 0.057 14.3 1.5 11.9 12 0 0 12 12 12 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KER27961.1 - 0.013 15.9 1.1 0.013 15.9 1.1 10.9 11 3 0 11 11 11 0 Zinc finger, C2H2 type DUF3039 PF11238.8 KER27961.1 - 0.041 13.7 1.1 0.38 10.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Sgf11 PF08209.11 KER27961.1 - 0.62 9.7 4.5 2 8.0 0.0 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KER27961.1 - 3.3 7.7 8.6 0.39 10.7 0.5 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type GRAB PF10375.9 KER27962.1 - 0.12 12.3 0.9 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 GRIP-related Arf-binding domain RasGEF PF00617.19 KER27963.1 - 1e-29 104.0 0.0 3.4e-29 102.3 0.0 1.9 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KER27963.1 - 0.0015 18.7 0.2 0.0061 16.8 0.2 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 KER27963.1 - 0.039 14.6 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain CDC27 PF09507.10 KER27964.1 - 5.1e-10 39.3 21.5 8e-10 38.7 21.5 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MMPL PF03176.15 KER27964.1 - 0.052 12.5 0.3 0.074 12.0 0.3 1.2 1 0 0 1 1 1 0 MMPL family CTP_transf_3 PF02348.19 KER27964.1 - 0.065 13.1 0.6 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 Cytidylyltransferase Peptidase_S64 PF08192.11 KER27964.1 - 0.19 10.2 5.5 0.23 9.9 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 KER27964.1 - 3.9 6.1 6.7 5.3 5.6 6.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F_actin_cap_B PF01115.17 KER27965.1 - 3.7e-99 331.2 0.0 4.6e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KER27965.1 - 0.054 12.9 0.0 0.15 11.5 0.0 2.0 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Arrestin_N PF00339.29 KER27967.1 - 2.7e-28 98.8 0.1 8.2e-11 42.2 0.0 3.3 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KER27967.1 - 4.2e-26 92.0 0.1 6.7e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF1126 PF06565.12 KER27968.1 - 0.053 13.3 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 DUF1126 PH-like domain Exo_endo_phos PF03372.23 KER27969.1 - 2.2e-06 27.4 0.0 4e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RING_2 PF13639.6 KER27971.1 - 2.8e-14 53.1 30.8 4.3e-10 39.7 1.7 3.8 3 0 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 KER27971.1 - 1e-07 31.6 1.3 1e-07 31.6 1.3 4.5 4 1 1 5 5 5 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KER27971.1 - 3.5e-06 26.8 1.9 3.5e-06 26.8 1.9 4.6 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER27971.1 - 4.5e-05 23.6 4.4 4.5e-05 23.6 4.4 4.1 3 2 0 3 3 3 1 RING-H2 zinc finger domain SWIM PF04434.17 KER27971.1 - 5.2e-05 22.8 0.6 0.00015 21.4 0.6 1.8 1 0 0 1 1 1 1 SWIM zinc finger Zn_ribbon_17 PF17120.5 KER27971.1 - 0.00011 21.8 0.4 0.00011 21.8 0.4 4.3 3 1 1 4 4 4 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KER27971.1 - 0.00013 21.9 19.2 0.00065 19.7 2.1 4.9 3 2 2 5 5 5 2 RING-type zinc-finger FANCL_C PF11793.8 KER27971.1 - 0.00031 20.9 17.5 0.0027 17.9 3.6 3.0 3 0 0 3 3 3 2 FANCL C-terminal domain zf-C3HC4 PF00097.25 KER27971.1 - 0.00061 19.6 0.6 0.00061 19.6 0.6 3.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER27971.1 - 0.001 19.1 8.3 0.076 13.1 0.6 3.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBR PF02207.20 KER27971.1 - 0.0014 18.8 9.5 0.0099 16.0 9.5 2.5 1 1 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 KER27971.1 - 0.0062 16.4 21.2 0.086 12.7 4.5 3.8 3 0 0 3 3 3 2 PHD-finger DUF2175 PF09943.9 KER27971.1 - 0.11 12.8 0.3 0.33 11.3 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Prok-RING_4 PF14447.6 KER27971.1 - 0.36 10.7 22.5 0.95 9.4 1.8 5.3 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KER27971.1 - 0.72 9.8 19.8 3.3 7.7 1.4 4.6 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 RecR PF02132.15 KER27971.1 - 2.5 7.7 18.6 0.96 9.1 0.6 4.7 4 1 0 4 4 4 0 RecR protein zf-RING_5 PF14634.6 KER27971.1 - 4.1 7.4 30.5 0.093 12.7 0.5 4.3 4 1 0 4 4 3 0 zinc-RING finger domain zf-C2H2_4 PF13894.6 KER27971.1 - 4.6 8.3 8.1 20 6.3 0.0 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger Glyco_tran_28_C PF04101.16 KER27972.1 - 1.1e-13 51.5 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain OCRE PF17780.1 KER27974.1 - 0.0054 16.7 0.4 0.017 15.1 0.4 1.8 1 0 0 1 1 1 1 OCRE domain Tubulin PF00091.25 KER27975.1 - 7.8e-39 133.9 0.0 1e-38 133.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 KER27975.1 - 0.00092 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Talin_middle PF09141.10 KER27976.1 - 1.5e-56 190.9 0.2 1.5e-56 190.9 0.2 9.0 7 3 0 7 7 7 1 Talin, middle domain FERM_M PF00373.18 KER27976.1 - 2.4e-27 95.7 0.2 9.8e-27 93.7 0.2 2.2 1 0 0 1 1 1 1 FERM central domain FERM_f0 PF16511.5 KER27976.1 - 1.1e-20 73.7 0.0 1.2e-17 64.0 0.0 2.7 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 KER27976.1 - 8.9e-18 64.0 0.7 4.2e-17 61.8 0.4 2.3 2 0 0 2 2 2 1 FERM N-terminal domain IRS PF02174.17 KER27976.1 - 2.6e-06 27.2 0.0 7.6e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DUF2277 PF10041.9 KER27976.1 - 0.018 15.4 0.8 1.6 9.2 0.1 4.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ubiquitin PF00240.23 KER27976.1 - 0.019 14.7 0.1 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin family Rop-like PF05082.13 KER27976.1 - 0.019 14.8 0.2 0.16 11.8 0.2 2.8 1 0 0 1 1 1 0 Rop-like Focal_AT PF03623.13 KER27976.1 - 0.037 14.0 8.3 0.15 12.0 0.2 5.0 5 0 0 5 5 5 0 Focal adhesion targeting region Rad60-SLD PF11976.8 KER27976.1 - 0.18 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like zf-C2H2 PF00096.26 KER27978.1 - 4.5e-11 42.6 18.9 4.6e-05 23.6 1.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER27978.1 - 1.8e-08 34.5 17.1 0.0053 17.5 1.1 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER27978.1 - 0.00054 20.3 0.7 0.00054 20.3 0.7 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KER27978.1 - 0.017 15.5 10.8 0.14 12.6 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER27978.1 - 0.059 13.7 9.7 4.1 7.8 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER27978.1 - 0.06 13.4 12.4 0.7 10.0 0.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER27978.1 - 2.7 8.4 8.6 5 7.5 0.2 3.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 KER27978.1 - 5.9 6.8 13.9 0.78 9.6 2.0 3.0 2 1 1 3 3 3 0 GAGA factor zf_C2H2_ZHX PF18387.1 KER27978.1 - 6.5 6.5 8.8 16 5.2 0.1 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DEAD PF00270.29 KER27980.1 - 8.5e-42 142.9 0.0 2e-41 141.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER27980.1 - 2.5e-28 98.6 0.4 5.4e-27 94.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER27980.1 - 8.4e-05 22.6 0.0 0.0026 17.8 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit MipZ PF09140.11 KER27980.1 - 0.066 12.5 1.0 0.15 11.3 1.0 1.5 1 0 0 1 1 1 0 ATPase MipZ PfkB PF00294.24 KER27981.1 - 2.2e-49 168.4 0.1 7.4e-36 124.0 0.0 2.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase PDZ PF00595.24 KER27982.1 - 4.1e-11 43.1 0.0 1.5e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KER27982.1 - 8.2e-11 41.6 0.2 2.3e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER27982.1 - 6.3e-05 23.2 0.1 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain zf-CCCH_2 PF14608.6 KER27984.1 - 5.1e-11 42.6 47.6 0.00014 22.2 4.3 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 KER27984.1 - 0.053 13.4 11.5 0.1 12.5 1.8 3.0 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Torus PF16131.5 KER27984.1 - 5 7.9 6.5 3 8.6 0.3 3.2 2 1 1 3 3 3 0 Torus domain zf-CCHH PF10283.9 KER27984.1 - 7.1 6.7 12.2 28 4.8 1.4 4.0 3 0 0 3 3 3 0 PBZ domain PI-PLC-X PF00388.19 KER27985.1 - 1.4e-61 206.3 0.0 1.4e-61 206.3 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KER27985.1 - 3.8e-42 143.2 0.8 3.8e-42 143.2 0.8 2.6 2 1 1 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 KER27985.1 - 4.2e-34 117.2 0.0 1.2e-33 115.8 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF1154 PF06631.11 KER27985.1 - 5.2e-16 58.4 1.5 5.2e-16 58.4 1.5 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1154) EF-hand_like PF09279.11 KER27985.1 - 2.4e-08 34.3 0.4 2.4e-08 34.3 0.4 3.1 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 KER27985.1 - 1.7e-07 31.4 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ribosomal_60s PF00428.19 KER27985.1 - 0.084 13.5 3.9 0.32 11.6 3.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_A32 PF04665.12 KER27987.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein LRR_4 PF12799.7 KER27988.1 - 0.0044 17.4 8.5 2.1 8.9 0.2 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER27988.1 - 0.012 16.0 5.1 0.51 11.1 0.2 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 KER27988.1 - 0.075 13.1 8.1 3.1 8.1 0.4 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Ion_trans PF00520.31 KER27989.1 - 2.3e-34 118.7 50.4 2e-32 112.4 25.1 2.2 2 0 0 2 2 2 2 Ion transport protein Skp1 PF01466.19 KER27989.1 - 8.6e-23 80.2 0.5 3.5e-22 78.3 0.4 2.1 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KER27989.1 - 5.6e-21 74.5 0.8 4.7e-09 36.3 0.5 2.8 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DUF3883 PF13020.6 KER27991.1 - 6.3e-05 22.9 0.0 0.0002 21.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) Oxidored_FMN PF00724.20 KER27991.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family HS1_rep PF02218.15 KER27992.1 - 0.059 13.7 0.4 0.1 13.0 0.1 1.6 2 0 0 2 2 2 0 Repeat in HS1/Cortactin EAR PF07897.11 KER27992.1 - 0.08 12.6 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Sortilin_C PF15901.5 KER27993.1 - 0.0029 18.0 0.0 0.0043 17.4 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal HAD_2 PF13419.6 KER27994.1 - 1.2e-12 48.3 0.0 1.5e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KER27994.1 - 0.037 14.3 0.1 1.4 9.2 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KER27994.1 - 0.13 12.4 0.0 19 5.5 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Peptidase_C13 PF01650.18 KER27995.1 - 2.5e-43 148.5 1.9 5.8e-36 124.3 0.5 2.2 2 0 0 2 2 2 2 Peptidase C13 family Peptidase_C14 PF00656.22 KER27995.1 - 0.00014 21.9 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 KER27996.1 - 4.8e-82 275.3 0.1 9e-82 274.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KER27996.1 - 2.7e-05 24.3 0.2 4.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Caspase domain Colicin_immun PF09204.10 KER27996.1 - 0.02 15.4 0.4 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Sulfotransfer_3 PF13469.6 KER27996.1 - 0.066 13.6 0.1 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 Sulfotransferase family UQ_con PF00179.26 KER27999.1 - 1e-42 145.1 0.0 1.6e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER27999.1 - 0.0054 16.4 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER27999.1 - 0.018 15.3 0.1 0.051 13.9 0.1 2.0 1 1 0 1 1 1 0 RWD domain CCDC142 PF14923.6 KER27999.1 - 0.26 10.0 1.0 0.39 9.4 1.0 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 RVT_1 PF00078.27 KER28000.1 - 1.5e-09 37.7 0.0 5e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Torus PF16131.5 KER28000.1 - 2.1e-07 31.6 6.6 0.0002 22.0 3.4 2.8 2 1 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 KER28000.1 - 6.2e-07 29.2 6.7 3.8e-05 23.5 0.7 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER28000.1 - 4.8e-06 26.4 5.2 4.8e-06 26.4 5.2 3.7 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 KER28000.1 - 3.6e-05 23.4 0.8 3.6e-05 23.4 0.8 3.7 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KER28000.1 - 0.0028 18.1 11.5 0.016 15.6 2.2 2.9 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KER28000.1 - 0.0074 16.5 0.6 0.37 11.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family DFRP_C PF16543.5 KER28000.1 - 0.039 14.5 0.0 0.039 14.5 0.0 3.8 3 2 1 4 4 4 0 DRG Family Regulatory Proteins, Tma46 RVT_1 PF00078.27 KER28001.1 - 0.041 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PINIT PF14324.6 KER28002.1 - 4.1e-25 88.8 0.0 1.2e-24 87.3 0.0 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KER28002.1 - 2e-20 72.3 5.5 2e-20 72.3 5.5 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KER28002.1 - 3e-05 23.8 2.5 3e-05 23.8 2.5 2.5 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-H2C2_2 PF13465.6 KER28007.1 - 9.1e-34 114.4 36.7 9.4e-09 35.3 0.7 7.5 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 KER28007.1 - 3.7e-19 68.0 42.1 0.00084 19.7 2.8 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER28007.1 - 2.2e-15 56.0 37.5 0.009 16.8 1.9 7.0 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER28007.1 - 5.2e-07 29.8 8.6 0.37 11.1 0.1 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER28007.1 - 1.8e-05 24.6 26.3 0.17 11.9 1.8 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER28007.1 - 0.0031 17.2 17.2 0.21 11.4 0.1 4.7 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KER28007.1 - 0.42 11.3 10.8 1.3 9.7 0.6 4.1 3 2 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KER28007.1 - 0.74 10.3 28.7 0.35 11.3 0.6 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER28007.1 - 4 7.8 14.8 0.74 10.2 2.7 3.5 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KER28007.1 - 8.1 6.5 15.4 0.026 14.4 2.2 3.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF629 PF04780.12 KER28007.1 - 8.1 4.8 6.1 9.5 4.6 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF629) OSTbeta PF15048.6 KER28008.1 - 0.5 10.5 2.2 0.61 10.2 0.1 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein HLH PF00010.26 KER28009.1 - 4.7e-16 58.5 0.1 1e-15 57.4 0.1 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 KER28009.1 - 0.011 16.9 3.6 0.011 16.9 3.6 3.0 2 1 1 3 3 3 0 Neuronal helix-loop-helix transcription factor Neur_chan_LBD PF02931.23 KER28010.1 - 4.9e-08 32.7 0.3 8.6e-08 31.9 0.3 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER28010.1 - 0.0022 18.1 6.0 0.0022 18.1 6.0 2.2 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DAP PF15228.6 KER28012.1 - 2.4e-16 60.7 2.6 3.6e-16 60.2 2.6 1.3 1 0 0 1 1 1 1 Death-associated protein zf-C2H2_4 PF13894.6 KER28015.1 - 3.9e-22 77.0 31.1 0.0018 19.0 0.2 6.7 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KER28015.1 - 4.3e-21 74.1 34.1 9.6e-05 22.6 0.2 6.7 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER28015.1 - 3.4e-14 52.5 30.4 0.0023 18.3 0.0 7.8 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER28015.1 - 2.2e-09 37.1 21.9 0.42 10.7 0.3 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 KER28015.1 - 4.2e-08 33.3 14.5 0.9 10.0 0.2 6.7 7 0 0 7 7 6 2 Zinc-finger of C2H2 type GAGA PF09237.11 KER28015.1 - 8.9e-07 28.6 4.1 0.14 12.0 0.3 3.8 3 0 0 3 3 3 3 GAGA factor zf-C2H2_11 PF16622.5 KER28015.1 - 1.5e-06 27.8 17.6 0.0023 17.7 0.1 5.1 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KER28015.1 - 6.2e-05 23.2 9.7 11 6.4 0.0 6.4 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KER28015.1 - 0.0001 23.0 18.3 0.1 13.3 10.4 3.4 3 1 0 3 3 2 2 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KER28015.1 - 0.0026 18.0 16.6 2.1 8.7 2.5 4.4 2 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 KER28015.1 - 0.0064 16.6 17.8 4 7.7 3.1 4.7 2 1 2 4 4 4 2 FYVE zinc finger BolA PF01722.18 KER28015.1 - 0.0067 16.7 3.2 1.3 9.4 0.4 3.7 2 1 3 5 5 5 1 BolA-like protein zf-C2H2_9 PF16293.5 KER28015.1 - 0.031 14.1 5.5 27 4.7 0.2 4.6 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Rubredoxin_2 PF18073.1 KER28015.1 - 0.12 12.2 0.4 0.12 12.2 0.4 3.6 3 0 0 3 3 3 0 Rubredoxin metal binding domain DUF1644 PF07800.12 KER28015.1 - 0.14 12.3 14.9 49 3.9 14.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Prok-RING_1 PF14446.6 KER28015.1 - 0.23 11.4 10.2 21 5.1 0.2 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-met2 PF12907.7 KER28015.1 - 0.38 10.9 16.5 3.1 8.0 0.0 5.4 5 2 1 6 6 6 0 Zinc-binding Actin_micro PF17003.5 KER28015.1 - 0.42 9.8 7.6 1.8 7.6 0.4 3.0 2 1 0 3 3 3 0 Putative actin-like family Zn-C2H2_12 PF18112.1 KER28015.1 - 0.64 10.5 0.0 0.64 10.5 0.0 4.0 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf_C2H2_ZHX PF18387.1 KER28015.1 - 1.7 8.3 7.1 14 5.5 0.1 3.8 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KER28015.1 - 1.8 9.0 19.5 29 5.1 0.9 5.6 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) UBZ_FAAP20 PF15750.5 KER28015.1 - 6.1 6.9 7.5 1.2e+02 2.7 0.0 4.5 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger COesterase PF00135.28 KER28016.1 - 3.2e-127 425.5 0.0 7.9e-127 424.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER28016.1 - 2.1e-05 24.5 0.9 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold MtrH PF02007.18 KER28016.1 - 0.21 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit TcpA PF05946.12 KER28017.1 - 0.061 13.4 0.0 0.07 13.3 0.0 1.0 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA UBA_4 PF14555.6 KER28018.1 - 1.3e-08 34.5 0.2 4.1e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 UBA-like domain DUF1296 PF06972.11 KER28018.1 - 0.0022 18.1 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) UBX PF00789.20 KER28018.1 - 0.0026 17.9 0.1 0.0083 16.3 0.1 1.9 1 1 0 1 1 1 1 UBX domain NolX PF05819.11 KER28018.1 - 0.18 11.1 1.0 0.29 10.4 1.0 1.2 1 0 0 1 1 1 0 NolX protein PC4 PF02229.16 KER28019.1 - 4.3e-24 83.9 0.4 6.1e-24 83.4 0.4 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Asp PF00026.23 KER28020.1 - 9e-25 87.7 0.0 1.1e-24 87.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER28020.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Avl9 PF09794.9 KER28021.1 - 9.5e-42 143.0 0.0 3.4e-26 91.9 0.0 3.6 3 1 0 3 3 3 3 Transport protein Avl9 Afi1 PF07792.12 KER28021.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 KER28021.1 - 0.14 12.1 0.2 0.44 10.5 0.1 1.8 1 1 0 1 1 1 0 DENN (AEX-3) domain Asp PF00026.23 KER28024.1 - 9.1e-21 74.6 0.0 6.1e-17 62.0 0.0 2.0 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER28024.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Serpin PF00079.20 KER28025.1 - 1.2e-96 324.3 0.7 1.3e-96 324.1 0.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Asp PF00026.23 KER28026.1 - 1.3e-51 175.9 0.0 1.5e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER28026.1 - 4.1e-07 30.4 0.0 0.00022 21.5 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER28026.1 - 0.0031 18.1 0.1 0.36 11.5 0.0 3.2 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KER28026.1 - 0.0071 16.9 0.0 0.095 13.3 0.0 2.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KER28026.1 - 0.037 13.8 0.0 0.13 12.1 0.0 1.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Serpin PF00079.20 KER28027.1 - 4.9e-52 177.5 2.6 1.2e-37 130.1 0.1 2.0 2 0 0 2 2 2 2 Serpin (serine protease inhibitor) CpcD PF01383.21 KER28027.1 - 0.099 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Asp PF00026.23 KER28028.1 - 1.8e-38 132.8 0.0 4e-23 82.3 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KER28028.1 - 0.0024 18.4 0.0 0.027 15.0 0.0 2.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER28028.1 - 0.02 15.5 0.0 0.2 12.3 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KER28028.1 - 0.088 12.6 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Serpin PF00079.20 KER28030.1 - 9.7e-69 232.4 0.0 4.3e-44 151.3 0.0 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) WD40 PF00400.32 KER28031.1 - 2.2e-25 88.4 11.2 0.00016 22.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat LIFR_N PF18207.1 KER28031.1 - 0.036 14.4 0.4 3.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor N-terminal domain KTI12 PF08433.10 KER28032.1 - 3.2e-58 197.4 0.0 4.1e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KER28032.1 - 2.2e-11 44.1 0.0 7.2e-11 42.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KER28032.1 - 0.035 14.5 0.3 0.12 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KER28032.1 - 0.041 14.1 0.0 0.088 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain YTH PF04146.15 KER28033.1 - 4.8e-40 137.2 0.1 1.1e-39 136.0 0.1 1.6 1 0 0 1 1 1 1 YT521-B-like domain DUF2277 PF10041.9 KER28034.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) RVT_1 PF00078.27 KER28035.1 - 1.2e-38 132.9 0.0 4.5e-34 117.9 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WAC_Acf1_DNA_bd PF10537.9 KER28035.1 - 4.7e-20 72.0 0.0 1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 KER28035.1 - 1.5e-12 47.6 0.1 3.8e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 KER28035.1 - 4.1e-10 40.0 0.0 6.1e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KER28035.1 - 2.8e-08 33.1 0.5 1.2e-07 31.1 0.5 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Dpy19 PF10034.9 KER28038.1 - 3.9e-128 428.5 0.0 1.6e-124 416.5 0.0 4.4 1 1 0 1 1 1 1 Q-cell neuroblast polarisation SP_C-Propep PF08999.10 KER28038.1 - 0.2 11.4 1.7 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide XPG_N PF00752.17 KER28039.1 - 4.6e-25 88.0 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KER28039.1 - 3.3e-22 78.7 0.0 1.4e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KER28039.1 - 0.0011 19.5 0.0 0.0037 17.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold PAPA-1 PF04795.12 KER28039.1 - 0.17 12.7 2.8 0.95 10.3 2.8 2.4 1 0 0 1 1 1 0 PAPA-1-like conserved region Metallophos PF00149.28 KER28041.1 - 2.1e-25 90.4 0.0 1.8e-16 61.3 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER28041.1 - 1.6e-16 60.4 1.5 4.6e-16 59.0 0.8 2.1 2 1 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF61 PF01886.16 KER28041.1 - 0.1 12.6 0.0 6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF61 IRF-2BP1_2 PF11261.8 KER28042.1 - 2.2e-30 104.0 3.2 1.8e-29 101.1 2.1 2.4 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger DUF3079 PF11278.8 KER28042.1 - 0.019 14.8 1.9 3 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) zf-C3HC4 PF00097.25 KER28042.1 - 0.068 13.1 1.1 0.23 11.4 1.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YbbR PF07949.12 KER28043.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 YbbR-like protein Hist_deacetyl PF00850.19 KER28046.1 - 2.1e-63 214.7 0.0 1.2e-42 146.5 0.0 2.5 2 1 0 2 2 2 2 Histone deacetylase domain Calcyon PF06387.11 KER28047.1 - 0.085 12.8 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) 7TM-7TMR_HD PF07698.11 KER28047.1 - 3.7 7.3 10.3 9.3 6.0 4.5 2.4 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase E1_DerP2_DerF2 PF02221.15 KER28051.1 - 4.8e-09 36.8 0.2 9.5e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 ML domain gag-asp_proteas PF13975.6 KER28052.1 - 5.5e-10 39.7 0.0 1.4e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER28052.1 - 8.5e-08 32.7 0.0 2.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 KER28052.1 - 0.00041 20.1 1.7 0.00096 18.9 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Peptidase_A2B PF12384.8 KER28052.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 KER28052.1 - 0.0024 17.6 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 KER28052.1 - 0.017 14.8 0.1 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVP PF00077.20 KER28052.1 - 0.018 15.3 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.6 KER28052.1 - 0.12 12.1 2.5 0.34 10.6 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KER28052.1 - 4 7.7 9.2 0.43 10.8 1.0 2.8 2 0 0 2 2 2 0 Zinc knuckle RMI2 PF16100.5 KER28055.1 - 1.7e-12 47.2 0.0 8.3e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 KER28055.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KER28055.1 - 0.032 14.4 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain BOF PF04076.13 KER28055.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein Asp PF00026.23 KER28056.1 - 5.3e-12 45.8 0.0 5.7e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KER28056.1 - 0.00038 21.0 0.0 0.00057 20.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER28056.1 - 0.0021 18.6 0.0 0.0039 17.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp PF00026.23 KER28057.1 - 3.1e-08 33.4 0.0 3.3e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 KER28058.1 - 5.6e-05 22.7 0.0 6.1e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ank_2 PF12796.7 KER28059.1 - 0.026 15.1 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) SOCS_box PF07525.16 KER28059.1 - 0.032 14.6 4.7 0.067 13.6 3.1 2.3 2 0 0 2 2 2 0 SOCS box E1_DerP2_DerF2 PF02221.15 KER28060.1 - 7.7e-16 58.7 0.3 8.9e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KER28061.1 - 0.0062 17.0 0.0 0.0089 16.5 0.0 1.3 1 0 0 1 1 1 1 ML domain Asp PF00026.23 KER28062.1 - 6.6e-34 117.7 0.0 7.5e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER28062.1 - 7e-05 23.1 0.0 0.31 11.3 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER28062.1 - 0.003 18.2 0.0 0.082 13.6 0.0 2.5 2 1 0 2 2 2 1 Aspartyl protease Pkinase PF00069.25 KER28064.1 - 3.8e-52 177.3 0.0 2.3e-20 73.1 0.0 5.1 4 1 1 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.17 KER28064.1 - 1.7e-26 93.0 0.0 5.4e-13 48.8 0.0 4.6 5 0 0 5 5 5 3 Protein tyrosine kinase RWD PF05773.22 KER28064.1 - 2.3e-08 34.3 0.0 5.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KER28064.1 - 8.3e-05 22.6 0.9 0.00022 21.3 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family tRNA-synt_His PF13393.6 KER28064.1 - 0.0019 17.5 0.0 0.0048 16.2 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Seadorna_VP7 PF07387.11 KER28064.1 - 0.043 12.9 0.1 0.083 11.9 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KER28064.1 - 2.3 7.1 5.5 0.48 9.3 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Na_K-ATPase PF00287.18 KER28066.1 - 2.3e-67 227.2 0.1 2.9e-67 226.8 0.1 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DUF5431 PF17496.2 KER28067.1 - 0.13 12.4 0.1 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5431) DUF5600 PF18150.1 KER28069.1 - 1.1e-40 138.5 0.7 5.3e-40 136.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 KER28069.1 - 3e-20 72.1 0.1 9.9e-20 70.4 0.1 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 KER28069.1 - 1.9e-13 50.8 0.0 1.6e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 KER28069.1 - 5.5e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 KER28069.1 - 2.9e-07 30.6 0.0 6.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KER28069.1 - 0.00063 19.1 0.1 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 KER28069.1 - 0.015 14.9 0.1 0.12 11.8 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 KER28069.1 - 0.019 14.9 0.0 0.1 12.6 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KER28069.1 - 0.022 15.2 0.2 0.17 12.4 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair RsgA_GTPase PF03193.16 KER28069.1 - 0.024 14.6 0.0 6.8 6.6 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase EF-hand_5 PF13202.6 KER28069.1 - 0.027 14.0 0.2 0.1 12.1 0.2 2.0 1 0 0 1 1 1 0 EF hand FeoB_N PF02421.18 KER28069.1 - 0.1 12.1 0.1 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 KER28069.1 - 0.11 11.8 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 AIG1 family AAA_24 PF13479.6 KER28069.1 - 0.15 11.7 0.2 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KER28069.1 - 0.17 12.1 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase zf-rbx1 PF12678.7 KER28075.1 - 0.032 14.5 2.9 0.065 13.5 2.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain rve PF00665.26 KER28078.1 - 8e-21 74.4 0.0 1.3e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER28078.1 - 4.1e-07 29.7 0.1 6e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KER28078.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 DDE domain dDENN PF03455.19 KER28079.1 - 7.1e-10 38.7 0.8 1.8e-09 37.4 0.8 1.8 1 0 0 1 1 1 1 dDENN domain DENN PF02141.21 KER28079.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 DENN (AEX-3) domain CAP_N PF01213.19 KER28080.1 - 2.3e-27 96.3 0.2 2.3e-26 93.0 0.0 2.0 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TetR_C_7 PF14246.6 KER28080.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain TFIIF_alpha PF05793.12 KER28082.1 - 5.4e-70 236.5 69.2 9e-58 196.2 14.2 3.9 1 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) rve PF00665.26 KER28082.1 - 1.1e-12 48.2 0.1 2.2e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER28082.1 - 2e-06 27.5 0.0 5.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain adh_short PF00106.25 KER28084.1 - 3e-23 82.3 0.7 1.5e-22 80.1 0.4 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER28084.1 - 1.7e-15 57.3 0.1 4.9e-14 52.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER28084.1 - 1.5e-07 31.5 0.2 2.3e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KER28084.1 - 1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KER28084.1 - 0.097 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Metallophos PF00149.28 KER28085.1 - 1.2e-34 120.7 0.0 1.6e-34 120.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER28085.1 - 0.00015 22.1 0.2 0.00033 21.0 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KER28085.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 7tm_3 PF00003.22 KER28086.1 - 7.1e-61 206.0 16.1 1e-60 205.4 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 KER28086.1 - 4.3e-07 29.8 8.6 8.5e-07 28.8 8.6 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR DUF2458 PF10454.9 KER28086.1 - 0.18 11.4 2.7 0.34 10.5 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) PdaC PF13739.6 KER28086.1 - 0.78 10.8 5.6 0.29 12.1 2.4 2.0 2 0 0 2 2 2 0 Deacetylase PdaC DctQ PF04290.12 KER28086.1 - 1.2 9.1 7.1 0.42 10.5 0.3 2.8 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ANF_receptor PF01094.28 KER28087.1 - 5.6e-70 236.2 0.0 6.6e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 KER28087.1 - 2.3e-07 30.8 0.1 4.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein NOA36 PF06524.12 KER28087.1 - 2.5 7.3 15.6 4.2 6.6 15.6 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KER28087.1 - 6.5 6.8 6.4 12 6.0 6.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 KER28087.1 - 6.9 7.0 8.6 15 5.9 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma_reg_N PF13800.6 KER28088.1 - 0.038 14.3 4.7 0.051 13.9 4.7 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Mycobact_memb PF05423.13 KER28088.1 - 0.1 12.5 0.4 0.15 12.0 0.4 1.2 1 0 0 1 1 1 0 Mycobacterium membrane protein TcpE PF12648.7 KER28088.1 - 0.12 12.9 2.1 0.18 12.4 2.1 1.2 1 0 0 1 1 1 0 TcpE family DUF929 PF06053.11 KER28088.1 - 0.39 10.0 4.8 0.44 9.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF4834 PF16118.5 KER28088.1 - 0.86 10.6 2.4 0.87 10.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3139 PF11337.8 KER28088.1 - 1.6 9.4 7.7 2.5 8.8 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) GDPD PF03009.17 KER28089.1 - 0.0036 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KER28089.1 - 0.042 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 KER28091.1 - 1.4e-21 77.4 0.0 2.4e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ribosomal_S10 PF00338.22 KER28091.1 - 2.9e-07 30.6 0.0 6.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CAP_GLY PF01302.25 KER28093.1 - 5.1e-18 64.9 0.7 8.9e-18 64.1 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KER28093.1 - 6e-07 29.7 9.6 0.0013 19.1 1.0 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KER28093.1 - 0.0019 18.1 5.4 1.2 9.4 0.2 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KER28093.1 - 0.025 15.1 3.0 13 6.8 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 KER28093.1 - 0.025 14.1 0.2 0.78 9.2 0.0 2.8 3 0 0 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.6 KER28093.1 - 0.14 11.9 10.2 3.7 7.4 1.1 4.9 3 3 1 4 4 4 0 Leucine rich repeat Forkhead PF00250.18 KER28097.1 - 5.5e-39 132.3 0.3 1.3e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Forkhead domain ATP-gua_Ptrans PF00217.19 KER28100.1 - 2.9e-33 115.2 0.0 6.7e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 KER28100.1 - 3e-05 24.3 0.0 7.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain zinc_ribbon_15 PF17032.5 KER28101.1 - 0.15 12.8 8.0 0.7 10.7 0.6 3.6 1 1 3 4 4 4 0 zinc-ribbon family zf-C2H2_4 PF13894.6 KER28101.1 - 0.28 12.1 25.4 0.64 11.0 0.2 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER28101.1 - 0.42 11.0 13.2 0.98 9.8 0.5 4.2 4 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 KER28101.1 - 0.99 9.4 8.7 12 5.9 0.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KER28101.1 - 1.6 8.9 9.2 45 4.3 0.0 4.4 4 0 0 4 4 4 0 Zinc ribbon domain SCAI PF12070.8 KER28102.1 - 3.4e-159 531.1 0.0 5.5e-158 527.2 0.0 1.9 2 0 0 2 2 2 2 Protein SCAI RhoGEF PF00621.20 KER28103.1 - 4e-21 76.1 0.1 7.1e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain FERM_C PF09380.10 KER28103.1 - 8.4e-21 74.2 0.6 1.7e-20 73.2 0.6 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.29 KER28103.1 - 6e-20 71.7 1.9 1.8e-10 41.3 0.1 3.0 3 0 0 3 3 3 2 PH domain FA PF08736.11 KER28103.1 - 1.2e-13 50.9 1.1 3.9e-13 49.2 1.1 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 KER28103.1 - 0.03 14.7 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 FERM central domain PH_8 PF15409.6 KER28103.1 - 0.12 12.7 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PLDc PF00614.22 KER28105.1 - 3.7e-12 45.9 2.7 1.6e-05 24.9 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KER28105.1 - 4e-12 46.1 0.1 2.4e-06 27.5 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PX PF00787.24 KER28105.1 - 0.00036 20.5 0.1 0.001 19.0 0.1 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.29 KER28105.1 - 0.042 14.4 0.4 0.14 12.7 0.4 1.9 1 1 0 1 1 1 0 PH domain Get5_C PF18514.1 KER28105.1 - 0.063 13.0 0.0 24 4.8 0.0 3.0 3 0 0 3 3 3 0 Get5 C-terminal domain Histone_H2A_C PF16211.5 KER28106.1 - 4.4e-17 61.5 1.5 9.1e-17 60.5 1.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KER28106.1 - 7.5e-15 55.4 0.0 9.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER28106.1 - 0.00014 22.1 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_7 PF13499.6 KER28109.1 - 9e-10 38.9 2.0 5.9e-09 36.3 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KER28109.1 - 1.1e-07 31.2 1.4 0.0026 17.5 0.1 3.0 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER28109.1 - 1.9e-06 27.0 0.1 0.04 13.5 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KER28109.1 - 6.8e-05 22.6 0.4 0.0017 18.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KER28109.1 - 0.00018 20.9 0.0 0.0036 16.7 0.0 2.6 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 KER28109.1 - 0.033 14.5 6.5 0.23 11.8 1.8 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER28109.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 EF hand Septin PF00735.18 KER28110.1 - 1.9e-120 401.4 0.3 2.8e-120 400.9 0.3 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KER28110.1 - 3.4e-10 40.1 0.1 2.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KER28110.1 - 1.2e-08 35.0 0.0 2.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER28110.1 - 6.1e-05 22.6 0.7 0.039 13.5 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KER28110.1 - 6.4e-05 22.4 0.5 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KER28110.1 - 0.0013 19.0 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KER28110.1 - 0.0033 17.5 2.6 1.6 8.8 0.1 3.2 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 KER28110.1 - 0.0046 17.2 0.1 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KER28110.1 - 0.0052 17.3 0.1 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 KER28110.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.6 KER28110.1 - 0.012 16.0 0.1 0.071 13.5 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 KER28110.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KER28110.1 - 0.033 13.7 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KER28110.1 - 0.044 13.5 0.1 0.096 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain THOC7 PF05615.13 KER28110.1 - 0.097 13.0 5.1 0.21 11.9 0.7 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 G-patch PF01585.23 KER28111.1 - 3.5e-05 23.6 1.1 6.5e-05 22.7 1.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KER28111.1 - 0.012 15.7 0.3 0.031 14.3 0.3 1.6 1 0 0 1 1 1 0 G-patch domain NCU-G1 PF15065.6 KER28115.1 - 3.4e-37 128.3 0.0 2.9e-36 125.2 0.0 1.9 1 1 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Gram_pos_anchor PF00746.21 KER28115.1 - 0.00059 19.7 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 LPXTG cell wall anchor motif G6B PF15096.6 KER28115.1 - 0.038 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 G6B family DUF4328 PF14219.6 KER28116.1 - 0.045 13.3 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Roc PF08477.13 KER28117.1 - 1.8e-19 70.2 0.0 4.7e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER28117.1 - 1.6e-17 63.6 0.0 1.8e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KER28117.1 - 3.1e-06 27.2 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KER28117.1 - 2e-05 24.1 0.0 0.00045 19.7 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER28117.1 - 0.00032 20.6 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KER28117.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KER28117.1 - 0.0036 17.8 0.1 0.0058 17.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KER28117.1 - 0.02 15.2 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KER28117.1 - 0.021 15.1 0.1 0.2 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 KER28117.1 - 0.037 13.1 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 KER28117.1 - 0.078 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KER28117.1 - 0.13 12.2 0.1 0.47 10.4 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KER28117.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MG3 PF17791.1 KER28119.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Macroglobulin domain MG3 ATG11 PF10377.9 KER28120.1 - 4.1e-07 30.1 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 11 ubiquitin PF00240.23 KER28120.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family RXT2_N PF08595.11 KER28120.1 - 0.073 13.1 2.6 0.22 11.5 2.6 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KER28120.1 - 3 8.3 15.9 9.1 6.7 15.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KER28120.1 - 5.1 7.5 12.2 14 6.1 12.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KER28120.1 - 5.3 5.0 9.3 9.8 4.1 9.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 KER28120.1 - 8.1 6.0 7.2 18 4.8 6.2 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting HbrB PF08539.11 KER28123.1 - 0.00047 20.2 0.7 0.0018 18.3 0.1 2.0 2 1 0 2 2 2 1 HbrB-like Sec7 PF01369.20 KER28124.1 - 9e-30 103.7 0.7 9.5e-11 41.7 0.0 3.4 2 1 1 3 3 3 3 Sec7 domain PH PF00169.29 KER28124.1 - 2.1e-18 66.8 0.1 3.5e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KER28124.1 - 6.6e-08 32.9 0.1 1.8e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KER28124.1 - 0.00047 20.2 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 KER28124.1 - 0.0033 17.7 0.0 0.051 13.9 0.0 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KER28124.1 - 0.092 13.0 0.0 0.7 10.2 0.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain Baculo_8kDa PF06096.11 KER28124.1 - 0.31 11.2 2.9 18 5.5 0.1 2.7 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein Complex1_LYR PF05347.15 KER28125.1 - 4.7e-11 42.6 0.5 7.7e-11 41.9 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KER28125.1 - 0.016 16.0 0.7 0.022 15.5 0.5 1.4 1 1 0 1 1 1 0 Complex1_LYR-like CENP-B_N PF04218.13 KER28125.1 - 0.08 12.6 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Fra10Ac1 PF09725.9 KER28127.1 - 7.3e-49 165.0 2.8 1.2e-48 164.3 2.8 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Kinesin PF00225.23 KER28129.1 - 1.6e-84 283.7 0.0 2.9e-84 282.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER28129.1 - 7.7e-19 68.1 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Cyclin_N2 PF16500.5 KER28129.1 - 0.32 11.7 2.9 0.3 11.8 0.5 2.2 2 0 0 2 2 2 0 N-terminal region of cyclin_N P_C PF06640.11 KER28129.1 - 5.7 7.0 9.7 13 5.8 9.7 1.5 1 0 0 1 1 1 0 P protein C-terminus I-set PF07679.16 KER28130.1 - 5.3e-46 154.6 0.0 3.9e-14 52.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 KER28130.1 - 6.2e-44 148.5 1.1 6e-13 49.2 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 KER28130.1 - 1e-26 93.0 0.1 6.5e-07 29.6 0.0 4.2 3 1 1 4 4 4 4 Immunoglobulin domain ig PF00047.25 KER28130.1 - 5.2e-20 71.4 0.0 0.00015 21.9 0.0 5.1 4 1 0 4 4 4 4 Immunoglobulin domain C2-set_2 PF08205.12 KER28130.1 - 3.9e-12 46.1 0.8 0.086 12.9 0.0 4.7 3 1 1 4 4 4 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KER28130.1 - 7.9e-10 38.9 0.3 0.031 14.4 0.0 5.6 5 2 1 6 6 6 2 Immunoglobulin V-set domain C1-set PF07654.15 KER28130.1 - 0.0012 19.2 0.0 2.3 8.6 0.0 4.1 3 1 1 4 4 4 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 KER28130.1 - 0.016 15.2 0.3 48 4.1 0.0 4.1 5 1 0 5 5 5 0 C17orf99 Ig domain Ig_4 PF16680.5 KER28130.1 - 0.019 15.2 0.0 0.18 12.1 0.0 2.6 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Porph_ging PF09697.10 KER28130.1 - 0.07 13.7 0.0 24 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Ig_5 PF16681.5 KER28130.1 - 0.16 12.4 0.1 2.6 8.5 0.0 3.0 5 0 0 5 5 5 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain P3A PF08727.11 KER28130.1 - 0.17 11.3 0.2 0.36 10.3 0.2 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like UL97 PF06734.12 KER28131.1 - 0.019 14.9 0.1 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 UL97 zf-CpG_bind_C PF12269.8 KER28131.1 - 7.5 6.3 8.7 9.4 5.9 0.4 2.7 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain Y_phosphatase PF00102.27 KER28132.1 - 1.5e-131 437.1 0.2 1.9e-41 142.1 0.0 4.4 4 0 0 4 4 4 4 Protein-tyrosine phosphatase fn3 PF00041.21 KER28132.1 - 5.1e-27 94.0 31.0 3.8e-08 33.6 0.2 11.0 9 2 1 10 10 10 4 Fibronectin type III domain Y_phosphatase3 PF13350.6 KER28132.1 - 1.7e-06 28.2 0.0 0.078 12.9 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 KER28132.1 - 2.2e-06 27.5 0.1 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KER28132.1 - 0.00087 19.4 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 KER28132.1 - 0.003 18.1 12.2 0.25 11.9 0.8 5.2 5 0 0 5 5 5 1 Purple acid Phosphatase, N-terminal domain Adeno_E3_CR2 PF02439.15 KER28132.1 - 0.022 14.5 0.5 0.059 13.1 0.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 KER28132.1 - 0.041 14.0 0.3 0.088 12.9 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SKG6 PF08693.10 KER28132.1 - 0.23 10.9 1.7 0.61 9.5 1.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain INCENP_ARK-bind PF03941.15 KER28134.1 - 0.083 12.9 0.7 0.31 11.0 0.7 2.0 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Presenilin PF01080.17 KER28134.1 - 2.6 6.7 3.6 3.9 6.1 3.6 1.3 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 KER28135.1 - 4.4e-21 75.3 0.1 7e-09 36.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER28135.1 - 5e-17 61.7 1.0 1.8e-09 37.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER28135.1 - 8.1e-17 61.4 1.8 4.8e-08 33.4 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KER28135.1 - 3.6e-15 55.6 7.0 5.1e-06 26.7 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat PDZ_6 PF17820.1 KER28135.1 - 1.2e-12 47.5 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 KER28135.1 - 4.8e-12 44.9 8.7 0.00042 20.5 0.0 6.9 8 0 0 8 8 8 2 Ankyrin repeat PDZ PF00595.24 KER28135.1 - 3.3e-09 37.0 0.0 6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER28135.1 - 5.2e-05 23.5 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 KER28135.1 - 0.088 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM Tricorn_PDZ PF14685.6 KER28135.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Apt1 PF10351.9 KER28136.1 - 4.8e-57 193.9 1.4 1e-29 103.8 0.0 3.9 4 0 0 4 4 4 3 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KER28136.1 - 2.1e-15 57.2 0.0 4.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KER28136.1 - 0.00029 20.8 0.4 0.0026 17.7 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2405) Fmp27_WPPW PF10359.9 KER28136.1 - 0.0018 17.2 0.0 0.0072 15.2 0.0 1.8 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain RVT_1 PF00078.27 KER28139.1 - 1.8e-16 60.4 0.0 2.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER28140.1 - 1.3e-59 201.7 0.0 3.2e-54 184.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER28140.1 - 4.9e-24 85.0 0.0 7.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER28140.1 - 0.037 13.3 0.0 0.095 12.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like PurS PF02700.14 KER28140.1 - 0.11 12.7 0.2 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF4806 PF16064.5 KER28140.1 - 0.12 12.6 0.0 43 4.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) YrbL-PhoP_reg PF10707.9 KER28140.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WD40 PF00400.32 KER28142.1 - 1e-45 152.7 31.6 3.5e-07 30.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28142.1 - 4.8e-09 36.4 0.4 0.2 12.0 0.0 4.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER28142.1 - 2.7e-05 23.0 6.7 0.052 12.2 0.1 4.9 3 1 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KER28142.1 - 0.0021 18.0 0.1 0.057 13.3 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KER28142.1 - 0.0056 15.3 0.0 0.13 10.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KER28142.1 - 0.011 15.7 1.4 9.9 6.2 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KER28142.1 - 0.11 11.4 0.0 25 3.7 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAPKK1_Int PF08923.10 KER28144.1 - 3.1e-26 91.5 0.0 6.2e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting SAM_2 PF07647.17 KER28148.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_5 PF13893.6 KER28150.1 - 1.4e-33 115.1 0.0 3.4e-28 97.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER28150.1 - 2.4e-19 68.9 0.0 2.3e-06 27.3 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 KER28150.1 - 7.8e-14 51.7 5.7 8.5e-09 35.6 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat RRM_8 PF11835.8 KER28150.1 - 3.5e-09 36.7 0.0 7.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain TPR_MalT PF17874.1 KER28150.1 - 6.7e-08 32.3 4.8 5.5e-05 22.7 1.7 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KER28150.1 - 1.2e-07 31.3 5.5 0.065 13.4 0.8 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER28150.1 - 3.4e-06 26.6 5.3 0.26 11.2 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER28150.1 - 0.00019 21.4 5.7 4.4 7.8 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER28150.1 - 0.00057 19.7 1.4 3 7.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER28150.1 - 0.0014 19.3 5.3 13 6.9 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_occluded PF16842.5 KER28150.1 - 0.0029 17.4 0.0 4 7.4 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif TPR_19 PF14559.6 KER28150.1 - 0.025 15.1 7.8 0.21 12.1 0.3 4.1 3 1 2 5 5 4 0 Tetratricopeptide repeat Limkain-b1 PF11608.8 KER28150.1 - 0.036 14.1 0.0 34 4.6 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 TPR_11 PF13414.6 KER28150.1 - 0.16 11.7 0.4 36 4.1 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 KER28150.1 - 0.28 11.3 1.4 1.2e+02 3.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER28150.1 - 8.6 6.7 10.7 0.87 9.9 4.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_5 PF13893.6 KER28152.1 - 1.9e-28 98.5 0.0 1.9e-25 88.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER28152.1 - 2e-19 69.2 0.0 8e-05 22.4 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KER28152.1 - 2.8e-07 30.7 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 KER28152.1 - 8e-05 22.4 0.0 1.5 8.7 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Secretin_N_2 PF07655.13 KER28152.1 - 0.017 15.6 0.8 0.017 15.6 0.8 3.6 4 0 0 4 4 4 0 Secretin N-terminal domain Limkain-b1 PF11608.8 KER28152.1 - 0.043 13.9 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Homeodomain PF00046.29 KER28153.1 - 1.6e-21 75.9 3.2 5.3e-21 74.2 3.2 2.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER28153.1 - 0.071 13.0 0.0 0.3 11.0 0.0 2.1 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 KER28153.1 - 0.19 11.6 0.2 0.68 9.8 0.1 1.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4698 PF15769.5 KER28155.1 - 6.6e-24 84.8 1.9 8.2e-24 84.5 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4698) DUF4698 PF15769.5 KER28156.1 - 2.3e-05 23.7 3.6 2.3e-05 23.7 3.6 1.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4698) ASC PF00858.24 KER28158.1 - 3.8e-41 141.5 1.3 3.8e-41 141.5 1.3 1.6 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel DUF3797 PF12677.7 KER28158.1 - 0.047 13.6 0.1 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) ASC PF00858.24 KER28159.1 - 1.3e-19 70.5 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4817 PF16087.5 KER28159.1 - 1.6e-06 27.8 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) HTH_IclR PF09339.10 KER28159.1 - 0.022 14.6 0.1 0.077 12.8 0.1 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Cation_ATPase_C PF00689.21 KER28161.1 - 1.8e-44 151.7 5.9 1.8e-44 151.7 5.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KER28161.1 - 8.9e-38 129.6 4.6 8.9e-38 129.6 4.6 3.4 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KER28161.1 - 1.9e-20 72.8 0.1 3.7e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KER28161.1 - 8.5e-20 70.2 0.6 8.1e-19 67.1 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KER28161.1 - 6.5e-19 69.0 0.1 1e-17 65.1 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KER28161.1 - 1e-06 28.7 0.6 1e-06 28.7 0.6 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KER28161.1 - 3.5e-05 24.3 0.0 0.00029 21.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3738 PF12543.8 KER28161.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) MFS_2 PF13347.6 KER28162.1 - 9.7e-19 67.2 30.7 1.2e-13 50.5 6.0 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KER28162.1 - 4.7e-15 55.4 12.2 7.4e-12 44.9 6.1 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KER28162.1 - 0.53 10.1 3.2 6.7 6.6 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage holin family HP1 tRNA-synt_His PF13393.6 KER28164.1 - 3.6e-23 82.3 0.3 2.3e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KER28164.1 - 5.1e-12 45.8 0.0 1.4e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KER28164.1 - 0.00047 19.7 0.3 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Med25 PF11232.8 KER28164.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Trehalose_PPase PF02358.16 KER28165.1 - 0.16 11.0 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Trehalose-phosphatase Aminotran_5 PF00266.19 KER28166.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KER28166.1 - 0.0071 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Isochorismatase PF00857.20 KER28167.1 - 4.1e-26 92.2 0.1 1.7e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Isochorismatase family Zip PF02535.22 KER28168.1 - 2.4e-59 201.2 12.5 1.7e-51 175.4 0.6 3.3 3 1 0 3 3 3 2 ZIP Zinc transporter DUF3325 PF11804.8 KER28168.1 - 0.027 14.6 0.5 0.027 14.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Holin_9 PF16936.5 KER28168.1 - 2.3 8.4 10.2 11 6.2 2.4 2.5 2 0 0 2 2 2 0 Putative holin MEIOC PF15189.6 KER28169.1 - 0.00055 19.6 0.9 0.0011 18.6 0.9 1.4 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC RVT_1 PF00078.27 KER28172.1 - 1.7e-42 145.4 0.0 3.7e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5641 PF18701.1 KER28172.1 - 4.3e-26 90.9 0.1 1e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Med25_VWA PF11265.8 KER28172.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A rve PF00665.26 KER28172.1 - 0.0003 21.0 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MauJ PF17419.2 KER28173.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Methylamine utilization protein MauJ adh_short PF00106.25 KER28176.1 - 6.9e-41 139.8 0.0 9e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER28176.1 - 1.2e-20 74.1 0.0 1.6e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER28176.1 - 9e-08 32.2 0.1 4.7e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KER28176.1 - 0.0091 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KER28176.1 - 0.047 13.8 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KER28176.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.13 KER28176.1 - 0.18 11.8 0.0 0.8 9.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.25 KER28178.1 - 1.3e-40 139.0 0.0 1.6e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER28178.1 - 1.4e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER28178.1 - 1.3e-07 31.7 0.2 6.9e-07 29.3 0.2 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KER28178.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CUB PF00431.20 KER28179.1 - 9.4e-49 164.3 0.3 3e-23 82.2 0.1 2.1 2 0 0 2 2 2 2 CUB domain IL4Ra_N PF09238.10 KER28179.1 - 0.0031 17.8 0.1 0.67 10.3 0.0 2.6 2 0 0 2 2 2 2 Interleukin-4 receptor alpha chain, N-terminal SLC35F PF06027.12 KER28180.1 - 1.3e-58 198.9 26.4 1.1e-57 195.8 26.4 2.2 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 KER28180.1 - 1.2e-07 32.0 35.1 0.0005 20.3 6.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family MANEC PF07502.14 KER28180.1 - 0.63 10.3 4.8 0.28 11.5 0.3 2.2 2 0 0 2 2 2 0 MANEC domain Ion_trans PF00520.31 KER28182.1 - 3.9e-16 59.0 41.1 4e-15 55.7 22.9 3.1 3 0 0 3 3 3 3 Ion transport protein MINDY_DUB PF04424.13 KER28182.1 - 0.036 14.1 0.4 0.17 11.9 0.1 2.2 2 0 0 2 2 2 0 MINDY deubiquitinase DUF4218 PF13960.6 KER28183.1 - 0.048 13.3 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RNase_T PF00929.24 KER28185.1 - 1.2e-34 120.3 0.0 1.4e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KER28185.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like Noggin PF05806.12 KER28186.1 - 1.1e-28 100.7 8.6 3.1e-28 99.2 8.6 1.7 1 1 0 1 1 1 1 Noggin DUF667 PF05018.13 KER28187.1 - 9.1e-88 292.8 0.2 1e-87 292.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) RNA_pol_3_Rpc31 PF11705.8 KER28189.1 - 1.3e-08 35.4 4.3 1.3e-08 35.4 4.3 2.1 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Nop25 PF09805.9 KER28189.1 - 0.71 10.3 8.7 4.6 7.7 0.5 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 KER28189.1 - 3.6 6.8 8.6 2 7.7 6.1 1.8 2 0 0 2 2 2 0 BUD22 7tm_1 PF00001.21 KER28191.1 - 9.2e-47 159.6 9.5 1.2e-46 159.2 9.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER28191.1 - 2e-06 27.6 14.8 3.5e-06 26.8 14.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KER28191.1 - 5.9e-06 25.9 6.9 1e-05 25.0 6.9 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Orthopox_A36R PF05950.11 KER28191.1 - 2 8.6 3.7 2.4 8.3 0.2 2.3 2 0 0 2 2 2 0 Orthopoxvirus A36R protein 7tm_1 PF00001.21 KER28192.1 - 7.3e-38 130.4 15.0 2e-25 89.6 6.7 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KER28193.1 - 1.4e-25 90.2 5.3 1.7e-25 89.9 5.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4500 PF14937.6 KER28193.1 - 0.042 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Asp PF00026.23 KER28194.1 - 8.5e-49 166.7 0.0 1e-48 166.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER28194.1 - 1.2e-07 32.2 0.1 4.3e-06 27.1 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER28194.1 - 0.0011 19.5 0.0 0.4 11.4 0.0 2.9 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KER28194.1 - 0.0022 17.8 0.0 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KER28194.1 - 0.084 13.5 0.0 13 6.5 0.0 3.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Cwf_Cwc_15 PF04889.12 KER28195.1 - 0.00073 19.3 9.8 0.00088 19.1 9.8 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KER28195.1 - 0.031 13.7 9.2 0.032 13.7 9.2 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KER28195.1 - 0.088 10.9 11.0 0.075 11.1 11.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KER28195.1 - 2.5 7.3 19.2 3 7.1 19.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KER28195.1 - 4.2 6.4 20.1 4.3 6.4 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KER28195.1 - 7.7 4.6 9.9 8.4 4.5 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KER28195.1 - 7.8 6.0 12.5 9.5 5.7 12.5 1.0 1 0 0 1 1 1 0 PPP4R2 DUF58 PF01882.18 KER28196.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF58 zf-C2H2_jaz PF12171.8 KER28197.1 - 4.7e-05 23.6 0.1 7.9e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER28197.1 - 0.00062 20.1 0.3 0.0011 19.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KER28197.1 - 0.0021 18.4 0.8 0.0077 16.6 0.1 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) ATXN-1_C PF12547.8 KER28199.1 - 0.0017 18.7 0.9 0.0023 18.2 0.9 1.2 1 0 0 1 1 1 1 Capicua transcriptional repressor modulator NUC173 PF08161.12 KER28200.1 - 1.8e-17 63.7 3.1 1.2e-15 57.7 0.1 3.5 3 0 0 3 3 3 2 NUC173 domain Importin_rep_3 PF18806.1 KER28200.1 - 0.04 13.9 0.7 3 8.0 0.0 4.2 5 0 0 5 5 5 0 Importin 13 repeat TAN PF11640.8 KER28200.1 - 0.13 12.4 3.8 0.61 10.2 0.0 4.0 3 1 1 4 4 4 0 Telomere-length maintenance and DNA damage repair zf-UBP PF02148.19 KER28203.1 - 0.00012 22.3 8.9 0.00012 22.3 8.9 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DisA_N PF02457.16 KER28203.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding UCH PF00443.29 KER28204.1 - 3.7e-47 161.0 0.0 5.5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER28204.1 - 3.2e-15 56.5 0.2 4.4e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KER28204.1 - 0.0035 16.8 1.0 0.06 12.8 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NUDIX PF00293.28 KER28205.1 - 2.6e-12 46.9 0.1 6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Pkinase_Tyr PF07714.17 KER28207.1 - 2.2e-75 253.3 0.0 3.4e-75 252.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER28207.1 - 4.6e-31 108.1 0.0 2.8e-30 105.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KER28207.1 - 0.012 15.7 0.0 0.044 14.0 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain SAM_2 PF07647.17 KER28211.1 - 2e-20 72.7 1.0 4e-12 46.1 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KER28211.1 - 2.8e-14 53.3 0.4 3.2e-10 40.3 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KER28211.1 - 2.4e-10 41.1 0.0 4.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain zf-H2C2_2 PF13465.6 KER28214.1 - 3.7e-12 46.1 6.9 5.6e-07 29.7 0.6 5.7 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 KER28214.1 - 1.1e-11 44.5 33.6 0.00015 22.1 3.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KER28214.1 - 2.9e-05 23.7 13.0 0.00034 20.3 0.5 4.0 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KER28214.1 - 0.0058 17.4 48.3 0.011 16.4 2.5 6.4 6 1 0 6 6 6 4 C2H2-type zinc finger Skp1_POZ PF03931.15 KER28215.1 - 3.1e-14 52.9 0.0 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Exo_endo_phos PF03372.23 KER28215.1 - 0.0074 15.8 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER28215.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Alpha_kinase PF02816.18 KER28217.1 - 1.1e-58 198.4 0.0 1.6e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family TPR_1 PF00515.28 KER28218.1 - 2.6e-16 58.6 0.3 2.9e-07 30.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER28218.1 - 4.3e-13 48.3 2.8 0.0039 17.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER28218.1 - 1.3e-07 31.1 0.1 0.1 12.3 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_12 PF13424.6 KER28218.1 - 7.4e-06 26.2 3.2 0.0024 18.1 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER28218.1 - 3.4e-05 24.4 0.9 0.024 15.3 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER28218.1 - 3.7e-05 23.6 2.9 0.14 12.4 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KER28218.1 - 3.8e-05 23.8 4.2 0.0053 16.9 1.7 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER28218.1 - 0.00033 21.1 4.2 0.086 13.4 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KER28218.1 - 0.0019 17.5 4.8 0.16 11.1 0.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER28218.1 - 0.0083 16.4 0.6 36 5.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KER28218.1 - 0.0089 16.8 2.2 28 5.9 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.15 KER28218.1 - 0.04 14.0 1.2 0.13 12.4 0.3 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Fis1_TPR_C PF14853.6 KER28218.1 - 0.075 13.1 1.5 44 4.2 0.0 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KER28218.1 - 0.093 12.6 1.6 7.3 6.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER28218.1 - 0.13 12.9 3.0 1.1e+02 3.7 0.3 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER28218.1 - 0.28 11.3 7.8 5.1 7.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KER28219.1 - 7.7e-37 127.3 0.0 9.7e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2628 PF10947.8 KER28219.1 - 0.041 14.2 2.5 9.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) SCAMP PF04144.13 KER28219.1 - 1.4 9.2 7.0 10 6.4 0.8 2.3 2 0 0 2 2 2 0 SCAMP family Lung_7-TM_R PF06814.13 KER28219.1 - 9.5 5.4 7.4 19 4.4 0.9 2.1 2 0 0 2 2 2 0 Lung seven transmembrane receptor SLBP_RNA_bind PF15247.6 KER28220.1 - 2e-25 88.7 3.6 6.4e-25 87.1 3.6 1.9 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain PHD PF00628.29 KER28220.1 - 0.00083 19.2 4.0 0.0017 18.2 4.0 1.5 1 0 0 1 1 1 1 PHD-finger Corona_3 PF04694.12 KER28222.1 - 0.1 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Coronavirus ORF3 protein TPR_2 PF07719.17 KER28226.1 - 3.6e-15 54.8 0.9 9.4e-07 28.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER28226.1 - 4.2e-15 54.8 0.2 1.6e-07 30.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER28226.1 - 1e-08 34.7 0.0 3.3e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KER28226.1 - 1.6e-07 31.6 0.7 0.0027 18.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER28226.1 - 6.3e-07 29.6 1.0 0.0077 16.5 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER28226.1 - 6.2e-06 26.0 0.0 8.5e-05 22.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER28226.1 - 9.8e-06 26.1 1.3 2.9e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KER28226.1 - 1.1e-05 25.5 0.5 4.8e-05 23.4 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER28226.1 - 0.00026 21.4 0.0 0.00026 21.4 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER28226.1 - 0.017 15.1 0.1 0.23 11.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER28226.1 - 0.043 14.5 0.0 0.34 11.6 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat ASH PF15780.5 KER28226.1 - 0.11 12.7 0.2 0.23 11.7 0.2 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DivIC PF04977.15 KER28227.1 - 0.00099 18.8 5.5 0.00099 18.8 5.5 9.0 4 2 5 10 10 10 4 Septum formation initiator FlaC_arch PF05377.11 KER28227.1 - 0.0031 17.9 4.0 0.0031 17.9 4.0 5.9 3 2 3 7 7 7 1 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KER28227.1 - 0.013 15.6 5.8 0.013 15.6 5.8 7.7 4 2 5 9 9 9 0 bZIP transcription factor CASP_C PF08172.12 KER28227.1 - 0.016 14.5 3.3 0.016 14.5 3.3 5.0 2 1 3 5 5 5 0 CASP C terminal Ribosomal_S8e PF01201.22 KER28229.1 - 2.1e-42 144.5 0.0 2.7e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e NHL PF01436.21 KER28230.1 - 4.4e-21 73.8 12.3 2.7e-06 27.1 0.0 6.3 6 0 0 6 6 6 4 NHL repeat zf-RING_UBOX PF13445.6 KER28230.1 - 4.3e-09 36.3 1.5 4.3e-09 36.3 1.5 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 KER28230.1 - 6.4e-06 26.2 6.5 6.4e-06 26.2 6.5 3.4 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4 PF00097.25 KER28230.1 - 7.1e-05 22.6 4.0 7.1e-05 22.6 4.0 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF5128 PF17170.4 KER28230.1 - 0.00011 21.5 0.4 0.048 12.8 0.0 3.1 3 0 0 3 3 3 1 6-bladed beta-propeller zf-C3HC4_4 PF15227.6 KER28230.1 - 0.00033 20.8 4.6 0.00033 20.8 4.6 4.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KER28230.1 - 0.004 17.0 2.7 0.004 17.0 2.7 3.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KER28230.1 - 0.013 15.3 4.6 0.013 15.3 4.6 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Mu-like_Com PF10122.9 KER28230.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.11 KER28230.1 - 0.97 9.4 6.7 3 7.8 3.8 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain bZIP_1 PF00170.21 KER28231.1 - 0.65 10.1 3.3 23 5.2 0.2 2.9 3 0 0 3 3 3 0 bZIP transcription factor Terminase_3C PF17288.2 KER28232.1 - 0.069 13.5 0.0 0.088 13.2 0.0 1.3 1 0 0 1 1 1 0 Terminase RNAseH like domain EB PF01683.18 KER28234.1 - 4.8e-05 23.6 10.8 0.021 15.1 4.7 2.3 1 1 1 2 2 2 2 EB module TIL PF01826.17 KER28234.1 - 0.084 13.1 13.7 0.37 11.1 2.4 2.4 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain D_CNTX PF17492.2 KER28234.1 - 0.3 11.3 12.7 0.38 11.0 1.7 2.3 2 0 0 2 2 2 0 Delta Ctenitoxins Laminin_EGF PF00053.24 KER28234.1 - 1.4 9.1 10.9 7.9 6.7 1.5 3.2 1 1 2 3 3 3 0 Laminin EGF domain DUF974 PF06159.13 KER28235.1 - 1.4e-53 182.2 0.0 2.3e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 KER28235.1 - 1.5e-07 31.2 0.2 0.047 13.1 0.0 4.1 3 1 1 4 4 4 3 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 KER28235.1 - 0.14 12.3 0.2 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TRAPPC9-Trs120 PF08626.11 KER28235.1 - 0.16 9.3 0.0 0.23 8.8 0.0 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SBF PF01758.16 KER28237.1 - 8.7e-16 58.2 5.1 8.7e-16 58.2 5.1 2.6 2 1 1 3 3 3 1 Sodium Bile acid symporter family OAD_beta PF03977.13 KER28237.1 - 0.0072 15.4 0.5 0.018 14.0 0.5 1.6 1 0 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit Mem_trans PF03547.18 KER28237.1 - 0.015 13.7 2.5 0.12 10.8 0.5 2.2 2 0 0 2 2 2 0 Membrane transport protein LapA_dom PF06305.11 KER28237.1 - 0.15 11.9 0.6 0.69 9.8 0.6 2.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Cadherin PF00028.17 KER28238.1 - 1.4e-78 259.4 0.4 1.1e-14 54.6 0.0 8.2 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER28238.1 - 3.9e-18 65.0 0.0 1.1e-09 38.0 0.0 5.5 5 0 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 KER28238.1 - 5.2e-05 23.2 6.9 0.27 11.2 0.2 5.1 5 0 0 5 5 5 2 Cadherin-like Cadherin_4 PF17803.1 KER28238.1 - 0.0034 18.0 7.1 0.089 13.4 0.2 4.0 3 0 0 3 3 3 2 Bacterial cadherin-like domain Alpha_E3_glycop PF01563.16 KER28238.1 - 0.41 10.7 6.9 9.9 6.3 0.7 3.0 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein 2-Hacid_dh_C PF02826.19 KER28240.1 - 1e-46 158.5 0.0 1.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CTP_transf_like PF01467.26 KER28240.1 - 4.2e-31 108.1 0.0 1.1e-30 106.7 0.0 1.8 1 0 0 1 1 1 1 Cytidylyltransferase-like 2-Hacid_dh PF00389.30 KER28240.1 - 1.1e-23 83.3 0.0 1.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Robl_LC7 PF03259.17 KER28240.1 - 0.00017 21.3 0.0 0.00056 19.6 0.0 1.8 1 0 0 1 1 1 1 Roadblock/LC7 domain NAD_binding_2 PF03446.15 KER28240.1 - 0.042 14.0 0.0 0.65 10.1 0.0 2.6 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sds3 PF08598.11 KER28241.1 - 5.6e-13 49.4 2.1 8.1e-13 48.9 2.1 1.3 1 0 0 1 1 1 1 Sds3-like zf-C4H2 PF10146.9 KER28241.1 - 0.0064 16.8 5.7 0.0091 16.3 5.7 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein RPN7 PF10602.9 KER28241.1 - 0.042 13.6 1.8 0.11 12.2 1.8 1.8 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Syntaxin-6_N PF09177.11 KER28241.1 - 0.4 11.3 5.2 0.16 12.6 0.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Acetyltransf_13 PF13880.6 KER28242.1 - 3.1e-26 91.2 0.0 5.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KER28242.1 - 1.3e-16 60.2 0.8 2.5e-16 59.2 0.8 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KER28242.1 - 0.0015 18.9 0.0 0.0046 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KER28242.1 - 0.0051 17.0 0.0 0.0087 16.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER28242.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-B_box PF00643.24 KER28243.1 - 1.7e-06 28.1 21.7 9.3e-06 25.7 10.3 5.0 6 1 0 6 6 6 2 B-box zinc finger PHD PF00628.29 KER28243.1 - 0.0012 18.7 7.0 0.0012 18.7 7.0 5.1 4 1 0 4 4 4 2 PHD-finger Tnp_zf-ribbon_2 PF13842.6 KER28243.1 - 0.0086 16.9 6.1 0.0086 16.9 6.1 4.7 5 1 0 5 5 5 1 DDE_Tnp_1-like zinc-ribbon DUF2408 PF10303.9 KER28243.1 - 0.026 15.1 0.7 2 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GDPD PF03009.17 KER28243.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family SKA2 PF16740.5 KER28243.1 - 0.23 11.3 2.2 0.39 10.5 0.1 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Gal-bind_lectin PF00337.22 KER28246.1 - 1.8e-05 24.3 0.0 4.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Galactoside-binding lectin Tis11B_N PF04553.12 KER28246.1 - 0.64 10.6 5.2 0.98 10.0 0.1 3.2 3 0 0 3 3 3 0 Tis11B like protein, N terminus Peptidase_M48_N PF16491.5 KER28247.1 - 2.3e-61 206.9 9.4 2.3e-61 206.9 9.4 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KER28247.1 - 2.6e-52 177.4 0.0 6.5e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 DNA_pol3_delta2 PF13177.6 KER28248.1 - 2e-08 34.2 0.1 3.9e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KER28248.1 - 4.5e-07 30.0 0.0 9.1e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KER28248.1 - 2.3e-05 24.9 1.6 0.00011 22.6 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KER28248.1 - 0.00024 21.5 0.0 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER28248.1 - 0.0046 17.2 0.6 0.01 16.1 0.2 1.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KER28248.1 - 0.016 14.9 0.1 0.051 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KER28248.1 - 0.02 14.7 0.1 0.029 14.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain Rep_fac_C PF08542.11 KER28248.1 - 0.046 14.1 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF2075 PF09848.9 KER28248.1 - 0.058 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KER28248.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta PF06144.13 KER28248.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RVT_1 PF00078.27 KER28249.1 - 0.0018 17.8 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.17 KER28250.1 - 9.1e-51 170.3 7.8 8.4e-11 42.2 0.1 9.0 6 2 0 7 7 7 6 Cadherin domain Invasin_D3 PF09134.10 KER28250.1 - 0.31 11.4 4.6 71 3.8 0.1 3.9 4 0 0 4 4 4 0 Invasin, domain 3 Mito_carr PF00153.27 KER28252.1 - 2.2e-52 175.0 0.3 5.5e-19 67.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos_2 PF14529.6 KER28253.1 - 2.5e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PLAT PF01477.23 KER28254.1 - 2e-233 760.4 34.8 2.4e-20 73.2 0.1 23.9 19 4 2 21 21 21 20 PLAT/LH2 domain DUF5585 PF17823.1 KER28254.1 - 0.1 11.6 4.7 0.29 10.0 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5585) DUF4357 PF14267.6 KER28255.1 - 2.4 8.2 4.8 13 5.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4357) Arm PF00514.23 KER28256.1 - 2.1e-20 72.1 18.7 3.3e-07 30.1 0.1 7.3 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 KER28256.1 - 0.0023 17.5 0.4 0.012 15.1 0.1 2.2 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 KER28256.1 - 0.018 15.4 3.2 0.66 10.4 0.4 3.6 3 2 0 3 3 3 0 HEAT repeats HEAT PF02985.22 KER28256.1 - 0.3 11.4 5.2 18 5.9 0.3 4.3 4 0 0 4 4 4 0 HEAT repeat FYVE_2 PF02318.16 KER28257.1 - 1.2e-06 28.7 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger C2 PF00168.30 KER28258.1 - 7e-37 125.9 0.0 2.6e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 C2 domain CPSase_L_D2 PF02786.17 KER28259.1 - 3.2e-71 239.2 0.0 4.9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KER28259.1 - 2.2e-42 144.0 0.5 5e-40 136.5 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KER28259.1 - 8.7e-33 112.7 0.0 2.4e-32 111.3 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KER28259.1 - 7.4e-15 54.5 0.0 1.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KER28259.1 - 3.1e-11 43.2 0.0 9.2e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KER28259.1 - 1e-09 38.0 0.0 0.00089 19.0 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KER28259.1 - 1.3e-08 34.6 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KER28259.1 - 1.6e-05 24.6 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KER28259.1 - 0.00015 21.0 0.0 0.17 11.1 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 KER28259.1 - 0.00019 20.8 0.0 0.077 12.2 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 KER28259.1 - 0.00032 21.4 0.1 0.11 13.2 0.0 2.9 2 1 1 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KER28259.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KER28259.1 - 0.067 13.4 0.2 8.5 6.6 0.0 3.5 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 MOZ_SAS PF01853.18 KER28261.1 - 3.2e-69 232.2 0.3 5.2e-69 231.5 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KER28261.1 - 3e-22 78.0 1.8 7.4e-22 76.7 1.8 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KER28261.1 - 7.6e-17 61.0 0.1 1.6e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-BED PF02892.15 KER28261.1 - 0.0038 17.2 0.1 0.0089 16.0 0.1 1.7 1 0 0 1 1 1 1 BED zinc finger Acetyltransf_7 PF13508.7 KER28261.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KER28261.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-met PF12874.7 KER28261.1 - 0.06 13.8 0.4 0.23 11.9 0.4 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KER28261.1 - 0.88 10.6 6.0 0.4 11.6 2.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_1 PF00078.27 KER28262.1 - 1.5e-09 37.7 0.0 3.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arm PF00514.23 KER28262.1 - 2.7e-06 27.2 0.2 0.02 14.9 0.1 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 KER28262.1 - 0.0029 16.9 0.3 0.099 11.9 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4704) PE PF00934.20 KER28262.1 - 0.1 13.0 0.4 25 5.3 0.1 2.4 2 0 0 2 2 2 0 PE family DUF3813 PF12758.7 KER28262.1 - 0.32 11.4 1.4 33 4.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) RVT_1 PF00078.27 KER28264.1 - 2e-11 43.8 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-ZPR1 PF03367.13 KER28265.1 - 1.2e-87 291.7 0.0 2.6e-46 157.4 0.0 3.1 2 1 1 3 3 3 2 ZPR1 zinc-finger domain HypA PF01155.19 KER28265.1 - 0.00017 21.5 0.8 0.11 12.5 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KER28265.1 - 0.011 15.8 0.7 6.1 6.9 0.0 3.0 2 1 0 2 2 2 0 CpXC protein zf-RRPl_C4 PF17026.5 KER28265.1 - 0.017 15.2 0.1 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-ribbon_3 PF13248.6 KER28265.1 - 0.041 13.3 9.3 7.5 6.1 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KER28265.1 - 0.046 13.7 1.1 0.39 10.7 0.0 2.3 2 1 0 2 2 2 0 zinc-ribbons zf-FPG_IleRS PF06827.14 KER28265.1 - 0.06 13.2 3.9 5.8 6.9 0.5 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS UPF0547 PF10571.9 KER28265.1 - 0.086 12.9 6.0 0.7 10.0 0.3 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.7 KER28265.1 - 0.097 13.1 1.6 73 3.9 0.0 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KER28265.1 - 0.17 12.3 0.7 88 3.6 0.1 3.4 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-ISL3 PF14690.6 KER28265.1 - 0.22 12.2 3.0 23 5.8 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.11 KER28265.1 - 0.43 10.5 2.7 7.3 6.6 0.1 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KER28265.1 - 0.57 10.3 8.7 16 5.7 3.8 3.9 3 1 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KER28265.1 - 0.61 10.1 4.9 9.4 6.3 0.2 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.7 KER28265.1 - 1 9.5 9.8 1.5 8.9 1.6 3.6 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KER28265.1 - 4.6 7.1 13.3 2.2 8.1 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain TPR_1 PF00515.28 KER28266.1 - 2.6e-30 103.0 5.4 0.00029 20.5 0.0 9.6 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 KER28266.1 - 6.5e-29 97.7 13.3 0.00031 20.6 0.1 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KER28266.1 - 1.1e-21 76.8 14.5 1.4e-16 60.5 1.2 6.0 5 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KER28266.1 - 1.1e-21 75.2 0.6 0.00072 19.6 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KER28266.1 - 6.3e-21 73.8 0.0 0.00017 21.2 0.0 8.4 6 3 3 9 9 9 6 TPR repeat TPR_14 PF13428.6 KER28266.1 - 2.1e-19 68.5 5.1 0.22 12.4 0.0 9.9 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KER28266.1 - 1.2e-16 60.7 16.9 0.018 15.3 0.1 8.4 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KER28266.1 - 2.1e-14 52.8 5.4 0.38 11.2 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER28266.1 - 1.4e-13 51.3 18.8 1e-06 29.2 0.4 7.9 6 2 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER28266.1 - 2.3e-13 50.5 8.6 0.0054 17.2 0.0 6.9 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KER28266.1 - 3.5e-10 39.9 5.5 0.6 10.9 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER28266.1 - 9.5e-08 31.6 13.6 0.014 15.4 0.0 7.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER28266.1 - 2.6e-07 30.7 4.8 0.016 15.4 0.1 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KER28266.1 - 0.00011 21.9 4.1 7.7 6.5 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 KER28266.1 - 0.6 8.8 2.5 13 4.4 0.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) GMP_PDE_delta PF05351.11 KER28267.1 - 4.3e-49 166.6 3.8 5e-48 163.1 3.8 2.2 1 1 0 1 1 1 1 GMP-PDE, delta subunit Cpn60_TCP1 PF00118.24 KER28268.1 - 2e-157 524.8 1.6 2.3e-157 524.6 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3402 PF11882.8 KER28269.1 - 1.3e-96 324.6 17.7 4.3e-59 200.8 7.0 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 KER28269.1 - 7.2e-36 123.8 0.9 1.9e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 N1221-like protein RVT_1 PF00078.27 KER28269.1 - 7.9e-06 25.5 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Replicase PF03090.17 KER28269.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Replicase family Abhydrolase_6 PF12697.7 KER28271.1 - 3.9e-26 93.0 0.1 1.3e-15 58.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KER28271.1 - 7.8e-12 45.4 1.3 1.6e-10 41.1 1.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER28271.1 - 2.7e-10 39.9 0.0 8.9e-10 38.2 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KER28271.1 - 7.4e-07 29.5 0.1 4.5e-06 26.9 0.0 2.2 3 0 0 3 3 3 1 Thioesterase domain PGAP1 PF07819.13 KER28271.1 - 3.9e-06 26.7 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein RVT_1 PF00078.27 KER28271.1 - 0.00035 20.2 0.0 0.00082 18.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Esterase PF00756.20 KER28271.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KER28271.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KER28271.1 - 0.024 14.5 1.3 0.1 12.5 1.3 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KER28271.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KER28271.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KER28271.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase CIA30 PF08547.12 KER28272.1 - 9.1e-22 77.8 0.0 3.7e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Aminotran_4 PF01063.19 KER28274.1 - 8.9e-17 61.7 0.0 1e-16 61.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV SHD1 PF03983.12 KER28274.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 DUF4350 PF14258.6 KER28274.1 - 0.091 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) IN_DBD_C PF00552.21 KER28274.1 - 0.12 11.6 0.1 5.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Integrase DNA binding domain Na_Ca_ex PF01699.24 KER28275.1 - 1e-21 77.5 20.8 1.9e-21 76.6 20.8 1.5 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KER28276.1 - 1.4e-14 54.3 1.4 1.9e-14 53.9 1.4 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein CobT PF06213.12 KER28277.1 - 0.011 15.1 8.2 0.016 14.6 8.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 KER28277.1 - 0.056 11.5 30.0 0.078 11.1 30.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 KER28277.1 - 0.34 10.1 6.5 0.47 9.6 6.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 KER28277.1 - 2 6.8 19.8 2.8 6.4 19.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 KER28277.1 - 2.8 7.8 15.5 4.7 7.0 15.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SGT1 PF07093.11 KER28277.1 - 8 4.8 10.5 11 4.3 10.5 1.1 1 0 0 1 1 1 0 SGT1 protein FAM176 PF14851.6 KER28278.1 - 0.016 14.9 1.5 0.018 14.7 1.5 1.2 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 KER28278.1 - 0.082 12.3 5.5 0.067 12.6 5.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KER28278.1 - 0.16 10.3 5.0 0.15 10.4 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KER28278.1 - 0.64 9.3 19.2 0.75 9.1 19.2 1.1 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 KER28278.1 - 0.76 8.2 6.5 0.65 8.5 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FYDLN_acid PF09538.10 KER28278.1 - 0.83 10.4 17.5 1.2 9.8 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PPP4R2 PF09184.11 KER28278.1 - 0.84 9.2 9.4 0.85 9.2 9.4 1.1 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 KER28278.1 - 0.95 9.3 5.9 0.86 9.5 5.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 KER28278.1 - 1.2 9.2 8.0 1.3 9.0 8.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 KER28278.1 - 4.4 6.3 23.9 5.4 6.0 23.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 KER28278.1 - 6.4 6.7 14.9 5.8 6.8 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KER28278.1 - 6.7 4.8 11.4 6.4 4.9 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family zf-nanos PF05741.13 KER28279.1 - 9.7e-45 150.6 12.9 3.4e-22 78.4 2.0 2.4 2 0 0 2 2 2 2 Nanos RNA binding domain Opy2 PF09463.10 KER28279.1 - 3.9 7.9 7.7 17 5.8 1.3 3.2 2 0 0 2 2 2 0 Opy2 protein SEP PF08059.13 KER28280.1 - 0.012 16.1 0.2 13 6.4 0.0 2.9 2 0 0 2 2 2 0 SEP domain Peptidase_M13_N PF05649.13 KER28281.1 - 5.9e-87 292.8 2.0 5.9e-87 292.8 2.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KER28281.1 - 1e-69 234.2 1.2 2.1e-69 233.2 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M13 Complex1_LYR PF05347.15 KER28281.1 - 0.031 14.3 2.5 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Pkinase PF00069.25 KER28283.1 - 1.4e-75 254.1 0.0 1.8e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER28283.1 - 1.3e-32 113.1 0.0 3.2e-32 111.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER28283.1 - 0.0018 17.3 0.1 0.0048 15.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER28283.1 - 0.0028 17.0 0.0 0.24 10.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 KER28283.1 - 0.0091 15.6 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family YqzE PF14038.6 KER28284.1 - 0.71 9.9 0.0 0.71 9.9 0.0 3.8 3 0 0 3 3 3 0 YqzE-like protein DUF4817 PF16087.5 KER28285.1 - 1.4e-11 44.0 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) Phage_antitermQ PF06530.12 KER28285.1 - 0.019 14.8 0.1 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 Phage antitermination protein Q Ig_3 PF13927.6 KER28286.1 - 7e-29 100.3 0.2 1e-14 54.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KER28286.1 - 6.5e-21 74.2 0.0 2.4e-11 43.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 KER28286.1 - 1.4e-19 70.0 0.0 1.8e-07 31.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KER28286.1 - 4.8e-15 55.7 0.3 4.3e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 KER28286.1 - 4.3e-06 26.9 0.1 0.15 12.2 0.0 3.8 3 1 1 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER28286.1 - 0.00075 19.5 0.1 1.4 9.0 0.0 3.3 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 KER28286.1 - 0.0019 17.7 0.0 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Ig_5 PF16681.5 KER28286.1 - 0.029 14.8 0.1 1 9.8 0.0 2.9 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Syntaxin PF00804.25 KER28287.1 - 0.11 12.2 0.2 4.3 7.0 0.0 2.3 2 1 1 3 3 3 0 Syntaxin Nop14 PF04147.12 KER28288.1 - 0.00032 19.1 25.7 0.00047 18.5 25.7 1.1 1 0 0 1 1 1 1 Nop14-like family CH PF00307.31 KER28288.1 - 0.00033 20.8 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain SDA1 PF05285.12 KER28288.1 - 0.001 18.6 26.2 0.0013 18.2 26.2 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KER28288.1 - 0.0071 14.7 18.5 0.012 14.0 18.5 1.4 1 0 0 1 1 1 1 CDC45-like protein IFT57 PF10498.9 KER28288.1 - 0.0092 15.0 4.0 0.017 14.1 4.0 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CH_2 PF06294.11 KER28288.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 CH-like domain in sperm protein SAPS PF04499.15 KER28288.1 - 0.97 8.1 5.1 1.3 7.7 5.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 KER28288.1 - 1.3 8.8 4.8 2 8.2 4.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Mpp10 PF04006.12 KER28288.1 - 2.9 6.2 26.6 4.7 5.5 26.6 1.2 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 KER28288.1 - 3.7 5.5 50.4 5.4 5.0 50.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KER28288.1 - 8.8 4.8 28.3 15 4.1 28.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 KER28289.1 - 3.1e-42 144.8 0.0 1.1e-29 103.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER28289.1 - 9.6e-22 77.5 0.0 7.2e-12 45.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER28289.1 - 0.0081 15.5 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KER28289.1 - 0.018 15.0 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-3CxxC PF13695.6 KER28291.1 - 0.044 14.3 0.0 13 6.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding domain DUF3830 PF12903.7 KER28291.1 - 0.19 11.4 0.0 22 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) HalOD2 PF18547.1 KER28291.1 - 0.31 11.0 5.3 8 6.5 0.5 2.8 2 2 0 2 2 2 0 Halobacterial output domain 2 Forkhead PF00250.18 KER28292.1 - 1.4e-25 89.4 0.4 2.7e-25 88.4 0.4 1.5 1 0 0 1 1 1 1 Forkhead domain FOXP-CC PF16159.5 KER28292.1 - 2.5e-18 66.5 0.1 6.8e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain MRP_L53 PF10780.9 KER28297.1 - 1.5e-08 34.7 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 PrmA PF06325.13 KER28298.1 - 3.9e-06 26.5 0.2 6.2e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KER28298.1 - 6.3e-05 23.6 0.1 0.0002 22.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER28298.1 - 8.4e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER28298.1 - 0.00053 19.8 0.0 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KER28298.1 - 0.02 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KER28298.1 - 0.04 14.5 0.1 0.17 12.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KER28298.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KER28298.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KER28298.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) COG7 PF10191.9 KER28299.1 - 6.1e-86 289.3 5.3 1.8e-53 182.0 0.4 4.3 2 1 0 3 3 3 3 Golgi complex component 7 (COG7) PrmA PF06325.13 KER28299.1 - 9.9e-06 25.1 0.1 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KER28299.1 - 8.5e-05 22.4 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER28299.1 - 0.0001 23.0 0.0 0.00039 21.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain COG5 PF10392.9 KER28299.1 - 0.00033 20.8 0.1 0.00087 19.5 0.1 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Methyltransf_31 PF13847.6 KER28299.1 - 0.00071 19.4 0.5 0.014 15.2 0.1 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER28299.1 - 0.019 15.6 0.0 0.095 13.4 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KER28299.1 - 0.027 13.4 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 KER28299.1 - 0.034 13.8 0.2 0.41 10.3 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MTS PF05175.14 KER28299.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain WEMBL PF05701.11 KER28299.1 - 0.072 11.8 0.3 0.13 10.9 0.3 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Methyltransf_18 PF12847.7 KER28299.1 - 0.19 11.7 0.3 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KER28299.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ras PF00071.22 KER28301.1 - 6.9e-59 198.1 0.1 1.6e-58 196.9 0.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER28301.1 - 2.2e-34 118.2 0.1 4.4e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER28301.1 - 1.3e-12 47.6 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family RVT_1 PF00078.27 KER28301.1 - 2.4e-09 37.0 0.0 1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.23 KER28301.1 - 3.2e-05 24.0 0.0 5.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cortex-I_coil PF09304.10 KER28301.1 - 0.0029 17.8 0.4 2 8.6 0.0 3.0 2 0 0 2 2 2 1 Cortexillin I, coiled coil Gtr1_RagA PF04670.12 KER28301.1 - 0.003 16.9 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KER28301.1 - 0.024 14.6 0.1 0.082 12.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KER28301.1 - 0.026 14.8 0.1 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KER28301.1 - 0.028 14.0 0.0 0.077 12.5 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MIS13 PF08202.11 KER28301.1 - 0.077 12.3 0.1 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Mis12-Mtw1 protein family HemN_C PF06969.16 KER28301.1 - 0.086 12.9 0.2 21 5.3 0.0 2.9 2 1 0 2 2 2 0 HemN C-terminal domain PduV-EutP PF10662.9 KER28301.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KER28301.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KER28301.1 - 0.65 10.4 4.9 0.6 10.5 0.7 2.8 1 1 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KER28303.1 - 4.2e-26 91.5 0.0 4.7e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER28303.1 - 2.2e-07 31.1 0.0 6.2e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER28303.1 - 0.00033 20.2 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RVT_1 PF00078.27 KER28305.1 - 2e-06 27.5 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER28308.1 - 1e-47 162.7 0.0 1.6e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER28308.1 - 3.3e-21 75.7 0.1 6.2e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GAS PF13851.6 KER28311.1 - 0.00014 21.3 18.6 0.00014 21.3 18.6 13.9 9 3 6 15 15 15 4 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KER28311.1 - 0.00029 21.4 10.8 0.00029 21.4 10.8 12.0 3 2 6 11 11 11 3 Fez1 Rootletin PF15035.6 KER28311.1 - 0.00086 19.4 11.7 0.00086 19.4 11.7 12.9 5 4 5 10 10 10 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 KER28311.1 - 0.0038 17.5 6.1 0.0038 17.5 6.1 14.5 4 2 9 14 14 14 5 Autophagy protein 16 (ATG16) SOGA PF11365.8 KER28311.1 - 0.012 16.7 3.1 0.012 16.7 3.1 16.9 5 3 12 19 19 19 0 Protein SOGA CmlA_N PF18456.1 KER28312.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain 7TM_GPCR_Srw PF10324.9 KER28313.1 - 1e-16 61.2 17.1 3.6e-13 49.5 3.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER28313.1 - 4.6e-14 52.4 14.2 1.4e-13 50.8 14.2 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0542 PF15086.6 KER28313.1 - 0.024 14.5 0.8 0.054 13.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Sgf11_N PF18519.1 KER28314.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain PSS PF03034.15 KER28315.1 - 1e-87 294.4 10.4 1.4e-87 293.9 10.4 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase NHL PF01436.21 KER28316.1 - 3.2e-21 74.2 4.9 2.6e-07 30.3 0.0 3.8 3 0 0 3 3 3 3 NHL repeat SGL PF08450.12 KER28316.1 - 0.00059 19.5 0.0 0.0022 17.6 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KER28316.1 - 0.0036 16.6 0.0 1.4 8.1 0.0 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Phytase-like PF13449.6 KER28316.1 - 0.027 14.4 0.0 9 6.1 0.0 2.8 2 1 0 2 2 2 0 Esterase-like activity of phytase SBBP PF06739.11 KER28316.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Beta-propeller repeat Aminotran_5 PF00266.19 KER28317.1 - 1.1e-36 126.6 0.0 3.7e-35 121.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V ELO PF01151.18 KER28322.1 - 1.2e-21 77.4 11.9 1.4e-21 77.2 11.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2070 PF09843.9 KER28322.1 - 0.13 10.6 2.5 0.14 10.5 2.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ELO PF01151.18 KER28323.1 - 7.3e-23 81.4 15.9 8.3e-23 81.2 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2070 PF09843.9 KER28323.1 - 0.048 11.9 2.3 0.048 12.0 2.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cpta_toxin PF07254.12 KER28323.1 - 0.34 10.9 2.9 0.44 10.5 2.9 1.2 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system Rod_C PF10493.9 KER28324.1 - 9e-11 40.9 0.0 7.5e-08 31.2 0.0 2.4 1 1 1 2 2 2 2 Rough deal protein C-terminal region RRM_1 PF00076.22 KER28326.1 - 6.5e-26 90.0 0.1 4.4e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER28326.1 - 3.3e-05 23.9 0.2 0.0035 17.4 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 KER28326.1 - 0.00096 19.0 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KER28326.1 - 0.028 14.0 0.0 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.20 KER28327.1 - 4.8e-28 97.8 0.0 7.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KER28327.1 - 6.3e-12 46.1 0.0 8.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KER28327.1 - 0.0095 16.3 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 zf-CSL PF05207.13 KER28328.1 - 1.2e-23 82.5 1.3 1.4e-23 82.3 1.3 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 KER28328.1 - 0.062 13.1 2.2 0.11 12.2 2.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain eIF-3c_N PF05470.12 KER28330.1 - 2.4e-156 521.5 36.5 6.2e-154 513.6 36.5 3.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KER28330.1 - 3.6e-10 40.3 1.2 2.1e-09 37.8 0.0 3.0 4 0 0 4 4 4 1 PCI domain SR-25 PF10500.9 KER28330.1 - 0.0083 15.8 18.9 0.019 14.6 9.7 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CHASE6_C PF17150.4 KER28330.1 - 0.14 12.8 0.2 11 6.8 0.1 3.1 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain Cullin PF00888.22 KER28332.1 - 4.2e-130 435.3 1.9 6e-130 434.8 1.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KER28332.1 - 5.9e-25 87.1 0.7 2.2e-24 85.3 0.1 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 KER28332.1 - 0.064 13.2 0.4 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 HbrB-like CSTF2_hinge PF14327.6 KER28333.1 - 9.2e-31 106.1 4.2 2e-30 105.1 4.2 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KER28333.1 - 1e-21 76.5 0.0 1.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KER28333.1 - 3.1e-20 71.5 7.8 1.2e-19 69.6 5.4 2.4 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 KER28333.1 - 0.2 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 KER28334.1 - 1.7e-42 145.6 0.0 6.1e-26 91.4 0.1 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER28334.1 - 4.6e-17 62.2 0.0 2.1e-13 50.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KER28334.1 - 4.5e-05 23.5 0.3 0.0007 19.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KER28334.1 - 0.005 16.5 0.1 0.0077 15.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KER28334.1 - 0.018 14.4 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 KER28334.1 - 0.052 13.2 0.3 0.89 9.1 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KER28334.1 - 0.074 12.4 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER28334.1 - 0.17 10.6 0.4 0.64 8.7 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase DEP PF00610.21 KER28335.1 - 1.5e-06 28.2 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IML1 PF12257.8 KER28337.1 - 7.5e-45 153.2 0.0 1.4e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 AAA_34 PF13872.6 KER28340.1 - 1.9e-138 460.4 0.0 2.8e-138 459.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 KER28340.1 - 9.8e-116 386.2 0.4 1.4e-115 385.6 0.4 1.2 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 KER28340.1 - 2e-05 24.6 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KER28340.1 - 0.14 12.5 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain LRR_8 PF13855.6 KER28343.1 - 1.1e-58 194.8 125.8 2.4e-10 40.0 0.6 9.1 3 3 9 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 KER28343.1 - 6.2e-39 131.4 90.4 2.5e-06 27.7 4.7 11.3 5 3 6 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER28343.1 - 3.8e-07 29.8 38.9 0.022 14.3 1.9 6.3 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KER28343.1 - 2e-05 24.5 84.9 0.44 11.3 0.7 17.5 17 2 1 18 18 18 6 Leucine Rich Repeat LRR_5 PF13306.6 KER28343.1 - 0.0006 19.8 11.4 0.04 13.9 2.7 4.0 4 1 1 5 5 5 2 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 KER28343.1 - 0.0034 17.4 6.1 20 5.3 0.1 6.7 7 3 2 9 9 9 1 RsmF rRNA methyltransferase first C-terminal domain CS PF04969.16 KER28345.1 - 0.042 14.9 0.0 0.068 14.2 0.0 1.4 1 1 0 1 1 1 0 CS domain Trm5_N PF18093.1 KER28347.1 - 0.032 14.1 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain VioE PF18234.1 KER28347.1 - 0.052 13.7 0.1 8.2 6.5 0.0 2.1 1 1 1 2 2 2 0 Violacein biosynthetic enzyme VioE FYRC PF05965.14 KER28349.1 - 1.2e-24 86.3 0.0 4.8e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 KER28349.1 - 2e-21 75.5 1.6 6.6e-21 73.9 1.6 2.0 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 KER28349.1 - 1.5e-16 61.2 0.9 5.7e-16 59.4 0.9 2.1 1 1 0 1 1 1 1 SET domain zf-HC5HC2H_2 PF13832.6 KER28349.1 - 1.6e-09 37.9 6.1 5.2e-09 36.2 6.1 1.9 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KER28349.1 - 1.6e-08 34.7 7.1 4.7e-08 33.2 7.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain mono-CXXC PF15626.6 KER28349.1 - 0.1 13.0 0.9 0.83 10.1 0.9 2.7 1 0 0 1 1 1 0 single CXXC unit COE1_DBD PF16422.5 KER28350.1 - 5.5e-118 392.5 4.4 8.7e-118 391.8 4.4 1.2 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 KER28350.1 - 5.3e-29 99.7 0.6 9.4e-29 98.9 0.6 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 KER28350.1 - 7e-08 32.4 0.1 2.5e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 IPT/TIG domain DUF866 PF05907.13 KER28352.1 - 0.035 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) PNTB PF02233.16 KER28353.1 - 8.7e-174 578.8 14.7 8.7e-174 578.8 14.7 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KER28353.1 - 1.1e-71 240.5 0.1 2.6e-71 239.3 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KER28353.1 - 5.7e-42 143.2 0.0 1.4e-41 142.0 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KER28353.1 - 6e-32 110.0 1.6 6e-32 110.0 1.6 4.3 4 2 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 KER28353.1 - 0.013 15.5 0.4 0.095 12.7 0.2 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KER28353.1 - 0.015 14.6 0.2 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KER28353.1 - 0.017 14.5 0.3 2.2 7.6 0.1 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KER28353.1 - 0.02 15.5 0.3 0.46 11.1 1.4 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KER28353.1 - 0.15 11.8 0.9 25 4.6 0.0 3.4 3 1 1 4 4 4 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 KER28353.1 - 1.3 9.3 6.1 0.85 9.9 0.7 3.4 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain CbtB PF09489.10 KER28353.1 - 9 6.5 6.5 4.6 7.4 0.1 3.6 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Bac_surface_Ag PF01103.23 KER28355.1 - 8.6e-25 87.9 0.1 1.1e-24 87.6 0.1 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 KER28355.1 - 0.063 13.9 1.2 0.11 13.1 1.2 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat 7tm_1 PF00001.21 KER28356.1 - 3.9e-10 39.5 12.6 6.9e-08 32.1 12.6 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER28356.1 - 1e-09 38.1 13.9 5.8e-05 22.5 7.2 3.1 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 KER28356.1 - 0.0009 18.7 9.9 0.0011 18.5 1.6 2.8 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM210 PF15195.6 KER28356.1 - 0.061 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 TMEM210 family V-ATPase_H_N PF03224.14 KER28360.1 - 1.5e-39 136.2 9.4 1.1e-33 116.9 0.1 3.2 3 0 0 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KER28360.1 - 1.7e-15 57.1 0.8 4.9e-15 55.7 0.5 1.9 1 1 0 1 1 1 1 V-ATPase subunit H CENP-B_dimeris PF09026.10 KER28360.1 - 0.05 14.0 15.4 0.12 12.8 15.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KER28360.1 - 0.28 10.9 1.1 0.73 9.5 1.1 1.7 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KER28360.1 - 7.3 5.8 18.8 1.6 8.0 14.5 2.1 3 0 0 3 3 3 0 NOA36 protein Rhabdo_ncap PF00945.18 KER28360.1 - 8.5 5.1 6.3 15 4.4 6.3 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein EF-hand_1 PF00036.32 KER28364.1 - 1.2e-33 112.1 6.4 3.1e-08 32.6 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER28364.1 - 3.3e-32 110.7 4.8 2e-15 57.0 0.9 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER28364.1 - 2.5e-28 96.3 5.7 6.3e-06 25.4 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER28364.1 - 1.1e-27 93.6 1.9 3.8e-06 26.4 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KER28364.1 - 2.3e-25 88.2 7.7 8.4e-13 48.0 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER28364.1 - 6.5e-10 39.3 0.1 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KER28364.1 - 1.1e-09 38.5 0.3 0.0012 19.2 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KER28364.1 - 3.7e-08 33.4 5.6 0.0013 18.9 0.1 3.5 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 KER28364.1 - 2.3e-06 27.5 0.7 0.03 14.3 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand PMBR PF09373.10 KER28364.1 - 0.0012 18.9 0.2 9.5 6.6 0.0 3.5 3 0 0 3 3 3 1 Pseudomurein-binding repeat Caleosin PF05042.13 KER28364.1 - 0.013 15.4 0.7 0.55 10.1 0.0 3.0 2 2 1 3 3 3 0 Caleosin related protein EF-hand_11 PF08976.11 KER28364.1 - 0.066 14.1 0.1 2.2 9.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Glyco_transf_64 PF09258.10 KER28365.1 - 3.4e-51 173.9 0.4 3.9e-51 173.7 0.4 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain LRR_4 PF12799.7 KER28369.1 - 9.8e-22 76.7 19.8 2.1e-07 31.1 2.3 5.4 2 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER28369.1 - 7.9e-17 60.8 16.4 3.3e-06 26.8 0.8 4.2 3 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 KER28369.1 - 4.3e-13 49.1 6.4 8.7e-06 25.3 1.0 3.9 2 2 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KER28369.1 - 0.0001 22.0 1.4 3.2 8.0 0.0 5.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KER28369.1 - 0.0075 16.7 14.6 46 5.1 0.2 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat DUF3760 PF12586.8 KER28369.1 - 0.02 15.1 0.9 2.8 8.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) CSD PF00313.22 KER28370.1 - 4.3e-15 55.3 0.0 5.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.23 KER28370.1 - 0.035 14.2 10.8 0.47 10.6 0.9 2.6 2 0 0 2 2 2 0 Zinc knuckle OB_RNB PF08206.11 KER28370.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-CCHC_4 PF14392.6 KER28370.1 - 1.1 9.1 9.0 4.3 7.1 0.7 2.5 3 0 0 3 3 3 0 Zinc knuckle Myb_DNA-bind_5 PF13873.6 KER28371.1 - 1.1e-13 51.1 2.2 2.3e-13 50.0 2.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KER28371.1 - 2.9e-06 27.6 0.2 5e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KER28371.1 - 0.0037 17.5 0.7 0.014 15.7 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 KER28371.1 - 0.049 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain CN_hydrolase PF00795.22 KER28372.1 - 5.5e-53 180.0 0.0 1.7e-50 171.8 0.0 3.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 KER28372.1 - 2.3e-20 73.1 0.1 5.9e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 HIT domain EF-hand_1 PF00036.32 KER28373.1 - 3e-27 92.1 8.1 0.00011 21.5 0.0 6.6 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 KER28373.1 - 3.1e-25 88.4 8.7 2.1e-08 34.5 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KER28373.1 - 2.5e-24 83.6 8.1 0.0002 20.7 0.0 6.8 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 KER28373.1 - 1.7e-20 71.2 14.5 0.00033 20.4 0.0 6.7 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 KER28373.1 - 2e-15 56.3 5.1 0.013 15.3 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER28373.1 - 7.8e-09 35.8 9.8 0.031 14.6 0.1 4.0 2 2 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KER28373.1 - 6.2e-07 29.2 3.1 1.4 8.9 0.0 5.3 4 1 0 4 4 4 2 EF hand Pox_F12L PF03337.13 KER28373.1 - 0.026 12.7 0.0 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein Dockerin_1 PF00404.18 KER28373.1 - 0.071 13.3 10.1 12 6.2 1.3 5.3 4 2 1 5 5 5 0 Dockerin type I domain DUF1707 PF08044.11 KER28373.1 - 0.11 12.6 1.0 17 5.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) PH PF00169.29 KER28374.1 - 1e-05 26.0 0.1 8.8e-05 23.0 0.1 2.4 1 1 0 1 1 1 1 PH domain Anillin PF08174.11 KER28374.1 - 2.6e-05 24.7 0.0 7.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin DUF3052 PF11253.8 KER28374.1 - 0.23 11.4 0.5 61 3.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3052) Myotub-related PF06602.14 KER28375.1 - 3.7e-73 246.5 0.0 3.1e-43 148.1 0.0 2.7 2 1 0 3 3 3 2 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 KER28376.1 - 3.5e-55 187.0 0.5 5.5e-55 186.3 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BROMI PF14961.6 KER28376.1 - 0.012 13.1 0.1 0.016 12.6 0.1 1.1 1 0 0 1 1 1 0 Broad-minded protein UPRTase PF14681.6 KER28379.1 - 2e-67 226.6 0.0 3.5e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 KER28379.1 - 1.9e-54 184.4 0.0 2.6e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KER28379.1 - 3.2e-05 24.5 0.0 6.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KER28379.1 - 6.4e-05 22.8 0.7 0.029 14.1 0.0 2.3 1 1 1 2 2 2 2 Cytidylate kinase AAA_33 PF13671.6 KER28379.1 - 0.0007 19.8 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 KER28379.1 - 0.0011 18.7 0.3 0.02 14.6 0.1 2.6 2 1 0 2 2 2 1 Dephospho-CoA kinase CPT PF07931.12 KER28379.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KER28379.1 - 0.0042 17.5 0.0 2.5 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KER28379.1 - 0.034 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UCH PF00443.29 KER28380.1 - 2e-41 142.2 0.0 3.8e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER28380.1 - 1.3e-15 57.8 0.4 4.3e-15 56.1 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FlhC PF05280.11 KER28380.1 - 0.47 10.2 4.1 0.21 11.3 0.2 2.0 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) zf-4CXXC_R1 PF10497.9 KER28380.1 - 3 8.1 8.9 0.65 10.2 4.8 2.0 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 SRP54 PF00448.22 KER28381.1 - 4.6e-47 160.2 0.3 3.8e-46 157.2 0.3 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KER28381.1 - 1.2e-44 153.4 9.1 1.2e-44 153.4 9.1 1.7 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 KER28381.1 - 1.4e-05 25.2 0.0 4.3e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Pcc1 PF09341.10 KER28381.1 - 3.8e-05 23.7 0.0 1.2 9.3 0.0 3.4 3 0 0 3 3 3 2 Transcription factor Pcc1 AAA_16 PF13191.6 KER28381.1 - 0.0004 20.8 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KER28381.1 - 0.00062 19.8 0.0 0.0038 17.3 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KER28381.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KER28381.1 - 0.022 14.5 0.1 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KER28381.1 - 0.025 14.8 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KER28381.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KER28381.1 - 0.059 12.5 0.1 0.2 10.8 0.0 1.9 1 1 1 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 KER28381.1 - 0.081 12.8 0.2 0.39 10.6 0.0 2.2 2 1 0 2 2 2 0 NTPase DDHD PF02862.17 KER28381.1 - 1.6 8.8 7.3 0.65 10.1 3.7 2.1 2 0 0 2 2 2 0 DDHD domain Hormone_recep PF00104.30 KER28382.1 - 9.6e-18 64.5 0.0 4.5e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KER28383.1 - 7.7e-29 100.0 18.0 1.5e-28 99.0 18.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Astro_capsid_p PF12226.8 KER28383.1 - 0.011 14.9 5.2 0.018 14.2 5.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 KER28383.1 - 0.013 15.5 3.7 0.17 11.9 2.7 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal Phage_holin_T PF11031.8 KER28383.1 - 0.02 14.4 0.1 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage T holin Hormone_recep PF00104.30 KER28383.1 - 0.041 13.5 0.0 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor FDC-SP PF15215.6 KER28383.1 - 0.13 12.9 0.0 38 4.9 0.0 2.8 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide DUF3245 PF11595.8 KER28383.1 - 5.4 7.5 13.2 0.84 10.1 7.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Sec7 PF01369.20 KER28385.1 - 3e-41 141.1 0.1 4.9e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KER28385.1 - 1.1e-32 112.9 0.0 4.3e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 KER28385.1 - 2e-06 28.2 0.2 0.0069 16.9 0.0 3.2 3 0 0 3 3 3 2 PH domain zf-PARP PF00645.18 KER28385.1 - 0.088 13.7 0.3 0.19 12.6 0.3 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF1275 PF06912.11 KER28388.1 - 0.029 14.3 2.4 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF308 PF03729.13 KER28388.1 - 0.42 11.0 9.3 1.1 9.7 2.8 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Peptidase_M24 PF00557.24 KER28389.1 - 3.1e-42 144.7 0.0 3.9e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KER28389.1 - 3.2e-10 40.1 2.7 1.1e-09 38.4 2.7 1.9 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding LRR_4 PF12799.7 KER28391.1 - 1.8e-12 47.2 15.9 0.00031 21.1 4.3 4.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER28391.1 - 2.8e-12 46.5 1.7 5.6e-12 45.5 1.7 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KER28391.1 - 1.4e-06 27.9 9.7 9.8e-05 22.0 0.2 3.8 2 1 3 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 KER28391.1 - 0.16 12.1 3.8 2.9 8.2 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeat zf-C2H2 PF00096.26 KER28392.1 - 1.3e-16 60.0 26.8 0.00031 21.0 0.2 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER28392.1 - 2.1e-12 46.7 24.7 0.0045 17.7 0.3 5.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER28392.1 - 0.00025 21.3 27.0 0.00076 19.8 1.2 5.6 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KER28392.1 - 0.0087 15.8 8.1 0.18 11.6 0.4 3.6 3 0 0 3 3 3 1 zinc-finger C2H2-type ADK_lid PF05191.14 KER28392.1 - 0.075 13.0 2.7 0.59 10.2 0.1 2.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 KER28392.1 - 0.082 13.6 12.8 0.79 10.4 0.0 4.6 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KER28392.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF1677 PF07911.13 KER28392.1 - 0.9 10.0 3.7 4.9 7.6 3.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) zf-C2H2_8 PF15909.5 KER28392.1 - 1.3 9.3 9.2 0.98 9.8 2.7 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KER28392.1 - 4.3 7.5 11.7 0.51 10.5 2.6 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 KER28392.1 - 4.6 7.3 19.7 2.2 8.4 2.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger EF-hand_7 PF13499.6 KER28393.1 - 6.3e-23 81.0 4.0 1.1e-15 57.9 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER28393.1 - 1e-20 71.7 10.5 5.3e-07 28.7 0.9 3.9 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER28393.1 - 6.5e-20 69.3 1.5 8.8e-06 25.3 0.2 4.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KER28393.1 - 4e-17 60.8 2.1 5.6e-05 22.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KER28393.1 - 1e-15 57.3 3.9 3.7e-07 29.9 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER28393.1 - 0.00012 22.4 0.7 0.061 13.6 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER28393.1 - 0.00087 19.2 2.0 1 9.4 0.1 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER28393.1 - 0.003 17.7 0.0 0.032 14.4 0.0 2.3 2 1 0 2 2 2 1 Dockerin type I domain MecA_N PF05223.11 KER28393.1 - 0.027 14.7 0.2 0.33 11.2 0.1 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain EF-hand_10 PF14788.6 KER28393.1 - 0.029 14.2 0.9 19 5.2 0.2 3.2 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.6 KER28393.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 KER28393.1 - 0.2 11.6 1.1 38 4.1 0.1 3.1 1 1 1 3 3 3 0 Caleosin related protein NAC PF01849.18 KER28394.1 - 9.8e-24 83.1 0.2 1.8e-23 82.3 0.2 1.4 1 0 0 1 1 1 1 NAC domain NAC PF01849.18 KER28395.1 - 4e-24 84.4 0.2 7.1e-24 83.5 0.2 1.4 1 0 0 1 1 1 1 NAC domain Noggin PF05806.12 KER28396.1 - 2.6e-28 99.4 4.5 6.6e-27 94.8 0.2 3.4 3 1 1 4 4 4 2 Noggin Anoctamin PF04547.12 KER28397.1 - 8.9e-115 384.1 1.1 4.4e-97 325.7 0.3 2.3 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 KER28397.1 - 1.1e-38 133.3 0.1 2.3e-27 96.2 0.2 4.0 3 1 0 3 3 3 3 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Arrestin_C PF02752.22 KER28400.1 - 5.1e-06 27.0 0.0 7.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Bcl-2 PF00452.19 KER28401.1 - 0.00071 20.2 0.1 0.0055 17.4 0.1 2.3 1 1 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family AAA PF00004.29 KER28403.1 - 2.8e-38 131.3 0.2 3e-37 128.0 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 KER28403.1 - 6.3e-32 111.0 0.4 9.1e-24 84.3 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M41 AAA_lid_3 PF17862.1 KER28403.1 - 4.1e-12 45.7 0.0 1.5e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KER28403.1 - 3e-05 24.5 0.7 0.009 16.4 0.1 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KER28403.1 - 9.9e-05 22.6 0.0 0.027 14.7 0.0 3.4 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 KER28403.1 - 0.0002 21.4 0.0 0.00092 19.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 KER28403.1 - 0.0018 18.6 0.2 0.0038 17.6 0.2 1.4 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.6 KER28403.1 - 0.0019 18.6 0.0 0.011 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER28403.1 - 0.0029 17.4 0.2 0.013 15.3 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KER28403.1 - 0.0036 17.1 0.7 0.099 12.4 0.0 2.5 2 1 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KER28403.1 - 0.0079 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KER28403.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KER28403.1 - 0.026 14.6 0.0 0.14 12.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KER28403.1 - 0.033 13.4 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 KER28403.1 - 0.06 13.3 0.2 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KER28403.1 - 0.064 13.3 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NAD_binding_1 PF00175.21 KER28403.1 - 0.1 13.2 0.0 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Mg_chelatase PF01078.21 KER28403.1 - 0.13 11.6 0.3 0.31 10.4 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KER28403.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KER28403.1 - 0.17 12.4 0.0 0.48 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Linker_histone PF00538.19 KER28404.1 - 2e-05 24.9 0.0 2.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 linker histone H1 and H5 family CUB PF00431.20 KER28405.1 - 8.4e-28 96.9 0.0 1.1e-18 67.5 0.0 2.0 2 0 0 2 2 2 2 CUB domain CC PF04942.14 KER28405.1 - 0.0084 16.3 0.0 8.1 6.7 0.0 2.6 2 0 0 2 2 2 2 CC domain Tim44 PF04280.15 KER28406.1 - 1.9e-26 92.9 0.1 9.5e-25 87.4 0.0 3.1 2 1 0 2 2 2 1 Tim44-like domain PPDK_N PF01326.19 KER28406.1 - 0.016 14.5 0.3 0.022 14.0 0.3 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF2267 PF10025.9 KER28406.1 - 0.066 13.5 0.4 0.15 12.4 0.4 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) EMC3_TMCO1 PF01956.16 KER28406.1 - 0.19 11.5 0.8 0.42 10.3 0.5 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1690 PF07956.11 KER28406.1 - 0.6 10.5 8.2 1.2 9.6 8.2 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Laminin_II PF06009.12 KER28406.1 - 1.1 9.3 6.6 2.2 8.3 6.6 1.6 1 0 0 1 1 1 0 Laminin Domain II TACC_C PF05010.14 KER28406.1 - 2.4 7.9 12.2 0.69 9.7 9.2 1.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prenyltrans PF00432.21 KER28407.1 - 6.8e-18 64.1 10.2 1.4e-07 31.1 0.1 5.8 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat DUF3902 PF13042.6 KER28407.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) PHO4 PF01384.20 KER28409.1 - 7.2e-34 117.3 0.0 9.7e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family BOP1NT PF08145.12 KER28410.1 - 1.7e-55 188.8 1.0 1.8e-54 185.4 1.0 2.4 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KER28410.1 - 9e-10 39.0 0.2 0.00019 22.1 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DsrD PF08679.11 KER28412.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Glyco_transf_18 PF15024.6 KER28413.1 - 2.7e-80 270.6 3.8 6e-46 157.2 0.0 4.8 3 1 1 4 4 4 4 Glycosyltransferase family 18 NIF PF03031.18 KER28414.1 - 1.6e-49 167.7 0.1 3.3e-49 166.7 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RVT_1 PF00078.27 KER28414.1 - 1e-29 103.7 0.0 1.8e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Frizzled PF01534.17 KER28419.1 - 2.1e-115 385.3 17.4 2.8e-115 384.8 17.4 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 KER28419.1 - 2e-33 115.3 6.1 2e-33 115.3 6.1 2.2 2 0 0 2 2 2 1 Fz domain Syndecan PF01034.20 KER28420.1 - 1.8e-26 91.8 0.0 4e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Syndecan domain Thyroglobulin_1 PF00086.18 KER28420.1 - 5.8e-05 22.7 1.1 9.8e-05 22.0 1.1 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Glycophorin_A PF01102.18 KER28420.1 - 0.00056 20.1 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 Glycophorin A YjeF_N PF03853.15 KER28421.1 - 4.5e-31 108.0 0.2 4.5e-18 65.7 0.0 2.2 1 1 1 2 2 2 2 YjeF-related protein N-terminus NPCBM_assoc PF10633.9 KER28421.1 - 0.25 11.6 0.5 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FERM_f0 PF16511.5 KER28423.1 - 7.1e-30 103.1 0.0 3e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 KER28423.1 - 2e-25 89.5 0.1 9.9e-25 87.2 0.1 2.4 2 0 0 2 2 2 1 FERM central domain Talin_middle PF09141.10 KER28423.1 - 4.6e-24 85.3 4.2 4.6e-24 85.3 4.2 12.0 10 3 3 13 13 13 2 Talin, middle domain I_LWEQ PF01608.17 KER28423.1 - 1.6e-15 57.6 124.1 7.1e-08 32.8 5.7 15.7 13 2 3 16 16 15 5 I/LWEQ domain VBS PF08913.10 KER28423.1 - 1.9e-12 47.7 34.5 1.4e-09 38.5 0.3 8.8 8 0 0 8 8 8 3 Vinculin Binding Site FERM_N PF09379.10 KER28423.1 - 8.8e-08 32.0 2.3 0.0048 16.8 0.1 3.8 3 0 0 3 3 3 2 FERM N-terminal domain RVT_1 PF00078.27 KER28423.1 - 5.9e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snapin_Pallidin PF14712.6 KER28423.1 - 0.011 16.1 12.7 0.031 14.7 0.2 6.0 6 0 0 6 6 5 0 Snapin/Pallidin CLZ PF16526.5 KER28423.1 - 0.025 14.9 2.0 11 6.5 0.1 4.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ubiquitin PF00240.23 KER28423.1 - 0.031 14.0 0.0 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin family IRS PF02174.17 KER28423.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Focal_AT PF03623.13 KER28423.1 - 0.17 11.8 4.0 2.4 8.2 0.0 5.2 6 0 0 6 6 6 0 Focal adhesion targeting region SipA_VBS PF17985.1 KER28423.1 - 0.22 11.5 0.5 4.6 7.3 0.0 3.4 3 0 0 3 3 3 0 SipA vinculin binding site TRPM_tetra PF16519.5 KER28423.1 - 0.33 11.1 2.7 18 5.5 0.5 2.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Elongin_A PF06881.11 KER28426.1 - 2e-19 70.1 0.9 2.9e-19 69.5 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 KER28426.1 - 2e-06 27.7 0.2 5.3e-06 26.4 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CsgA PF17334.2 KER28426.1 - 0.034 14.9 0.0 0.074 13.8 0.0 1.5 1 0 0 1 1 1 0 Minor curli fiber component A DUF4520 PF15016.6 KER28427.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF2054 PF10218.9 KER28428.1 - 2.8e-25 88.9 17.1 2.8e-25 88.9 17.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2054) RVT_1 PF00078.27 KER28428.1 - 0.036 13.6 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) 14-3-3 PF00244.20 KER28429.1 - 1.8e-86 289.3 1.1 2.5e-86 288.7 1.1 1.2 1 0 0 1 1 1 1 14-3-3 protein ACDC PF14733.6 KER28429.1 - 0.0057 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal HBM PF16591.5 KER28429.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain HLH PF00010.26 KER28431.1 - 4.1e-11 42.7 1.6 1e-10 41.4 1.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain EBV-NA3 PF05009.12 KER28431.1 - 0.048 13.2 0.4 0.082 12.4 0.4 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PAN_1 PF00024.26 KER28435.1 - 0.0018 18.2 2.6 0.0018 18.2 2.6 1.8 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 KER28435.1 - 0.023 14.5 2.6 0.059 13.2 2.6 1.7 1 0 0 1 1 1 0 PAN-like domain TIL PF01826.17 KER28435.1 - 0.42 10.9 5.4 0.63 10.3 4.8 1.6 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain PAN_2 PF08276.11 KER28435.1 - 0.48 10.6 5.7 1.1 9.4 5.5 1.7 1 1 1 2 2 2 0 PAN-like domain MAR_sialic_bdg PF10564.9 KER28435.1 - 1.7 8.8 9.6 0.64 10.1 4.2 2.3 1 1 1 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Archease PF01951.16 KER28436.1 - 4.6e-30 104.7 0.6 1.6e-27 96.4 0.6 2.9 1 1 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Leo1 PF04004.13 KER28437.1 - 1.7e-50 171.1 0.0 4.7e-50 169.7 0.0 1.8 1 0 0 1 1 1 1 Leo1-like protein DUF4241 PF14025.6 KER28439.1 - 0.025 14.9 0.1 0.035 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Med6 PF04934.14 KER28440.1 - 1.7e-40 137.9 0.0 2.3e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Homeodomain PF00046.29 KER28442.1 - 1.4e-12 47.3 0.2 7.5e-12 44.9 0.2 2.1 2 0 0 2 2 2 1 Homeodomain Cas1_AcylT PF07779.12 KER28443.1 - 6.4e-120 401.3 34.9 2e-47 162.2 8.1 4.5 4 1 0 4 4 4 4 10 TM Acyl Transferase domain found in Cas1p Glycos_transf_2 PF00535.26 KER28444.1 - 3.9e-25 88.6 0.0 2.1e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KER28444.1 - 0.0021 18.3 0.1 0.0039 17.4 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KER28444.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase UCH PF00443.29 KER28445.1 - 1.7e-94 316.1 0.3 8e-35 120.6 0.0 4.2 4 0 0 4 4 4 4 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER28445.1 - 1.3e-12 48.0 3.1 0.082 12.5 0.1 4.6 4 1 1 5 5 5 4 Ubiquitin carboxyl-terminal hydrolase ATP_bind_3 PF01171.20 KER28445.1 - 6e-12 45.7 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family USP8_dimer PF08969.11 KER28445.1 - 1.9e-08 34.5 0.3 4.4e-08 33.3 0.3 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 KER28445.1 - 0.0023 18.5 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PspB PF06667.12 KER28445.1 - 0.091 12.8 3.4 7.4 6.7 0.3 2.4 2 0 0 2 2 2 0 Phage shock protein B DUF1690 PF07956.11 KER28445.1 - 2.1 8.8 7.7 67 3.9 0.2 3.4 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) zf-HC5HC2H_2 PF13832.6 KER28448.1 - 1.2e-25 89.8 3.1 1.2e-25 89.8 3.1 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KER28448.1 - 3.2e-16 59.4 1.0 3.2e-16 59.4 1.0 3.4 2 1 1 3 3 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KER28448.1 - 2.4e-10 39.8 3.7 2.4e-10 39.8 3.7 3.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KER28448.1 - 1.1e-06 28.4 25.1 1.3e-06 28.2 7.1 3.4 3 0 0 3 3 3 2 PHD-finger GIY-YIG PF01541.24 KER28448.1 - 0.0021 18.3 0.1 0.004 17.4 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain C1_1 PF00130.22 KER28448.1 - 0.003 17.4 2.2 0.003 17.4 2.2 4.7 5 0 0 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ycf34 PF10718.9 KER28448.1 - 0.033 14.9 0.0 0.15 12.8 0.0 2.1 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 Sas6_CC PF18594.1 KER28448.1 - 0.12 12.2 1.7 0.22 11.4 1.7 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain PHD_4 PF16866.5 KER28448.1 - 0.26 11.4 12.0 0.19 11.9 3.7 3.0 2 0 0 2 2 2 0 PHD-finger FliD_N PF02465.18 KER28448.1 - 6 7.6 6.8 0.64 10.7 0.3 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FYVE_2 PF02318.16 KER28448.1 - 9 6.5 19.1 2.1 8.6 9.2 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger RUN PF02759.19 KER28449.1 - 6.6e-15 55.3 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 RUN domain FAM199X PF15814.5 KER28449.1 - 0.36 9.8 5.3 0.84 8.6 5.3 1.6 1 0 0 1 1 1 0 Protein family FAM199X PDZ_6 PF17820.1 KER28451.1 - 4.6e-09 36.0 0.0 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KER28451.1 - 2.8e-05 24.4 0.0 5.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KER28451.1 - 0.0007 19.3 0.2 0.0019 17.9 0.2 1.8 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.6 KER28451.1 - 0.0012 19.2 0.0 0.0067 16.7 0.0 2.2 1 1 1 2 2 2 1 PDZ domain Guanylate_kin PF00625.21 KER28452.1 - 5.4e-27 94.6 0.0 9.2e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase RVT_1 PF00078.27 KER28452.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arylsulfotran_N PF17425.2 KER28453.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain Dynein_light PF01221.18 KER28455.1 - 5.6e-32 109.9 0.6 6.9e-32 109.6 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Sigma70_ner PF04546.13 KER28456.1 - 0.0047 16.8 4.7 0.006 16.5 4.7 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KER28456.1 - 0.0059 14.8 17.9 0.0072 14.5 17.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 KER28456.1 - 0.019 13.3 7.2 0.023 13.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER28456.1 - 0.12 10.6 10.2 0.13 10.4 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2796 PF10986.8 KER28456.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SDA1 PF05285.12 KER28456.1 - 0.22 10.9 11.3 0.25 10.7 10.8 1.4 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 KER28456.1 - 0.54 9.5 25.9 0.91 8.8 25.9 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 KER28456.1 - 0.93 8.8 8.6 1.1 8.5 8.6 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 KER28456.1 - 1.8 8.3 5.4 2.4 8.0 5.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RXT2_N PF08595.11 KER28456.1 - 2.3 8.2 11.6 1.9 8.5 9.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal PPP4R2 PF09184.11 KER28456.1 - 2.9 7.4 12.1 4 7.0 12.1 1.2 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 KER28456.1 - 5.7 5.4 9.9 6.8 5.1 9.9 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2457 PF10446.9 KER28456.1 - 8.9 5.3 32.6 12 4.9 32.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Y_phosphatase PF00102.27 KER28457.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase COPIIcoated_ERV PF07970.12 KER28458.1 - 1.2e-76 257.4 0.7 1.7e-76 257.0 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter RT_RNaseH PF17917.1 KER28458.1 - 9.5e-22 77.3 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER28458.1 - 3e-19 68.9 0.0 6.9e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KER28458.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIH1_CS PF18201.1 KER28463.1 - 1.2e-09 38.5 0.1 2.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain Pih1_fungal_CS PF18482.1 KER28463.1 - 0.098 13.2 0.5 0.22 12.1 0.5 1.7 1 0 0 1 1 1 0 Fungal Pih1 CS domain HSP70 PF00012.20 KER28465.1 - 3.9e-71 240.0 1.4 2.3e-67 227.6 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KER28465.1 - 0.029 13.2 0.0 0.8 8.5 0.0 2.4 2 0 0 2 2 2 0 MreB/Mbl protein zf-C2HC_2 PF13913.6 KER28466.1 - 3.3e-09 36.4 10.1 0.00042 20.1 1.0 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type DZR PF12773.7 KER28466.1 - 0.0013 18.7 0.7 0.0013 18.7 0.7 3.2 3 0 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KER28466.1 - 0.0094 15.3 2.0 0.0094 15.3 2.0 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KER28466.1 - 0.28 11.0 9.5 9.3 6.1 9.5 2.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KER28466.1 - 0.49 11.2 6.3 0.24 12.2 0.6 2.6 3 0 0 3 3 2 0 zinc-ribbon family PLATZ PF04640.14 KER28466.1 - 0.64 10.7 3.5 23 5.7 0.3 3.5 4 0 0 4 4 3 0 PLATZ transcription factor ATAD4 PF15321.6 KER28466.1 - 0.64 11.4 4.4 0.55 11.6 0.2 2.8 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Zf_RING PF16744.5 KER28466.1 - 1.5 8.9 4.7 11 6.2 0.2 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C2H2_4 PF13894.6 KER28466.1 - 2.5 9.2 15.5 3.2 8.8 1.5 4.2 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KER28466.1 - 5.1 7.8 11.0 17 6.1 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type NOB1_Zn_bind PF08772.11 KER28466.1 - 5.9 7.1 9.8 0.11 12.7 1.4 2.5 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 KER28466.1 - 9.7 6.3 10.4 3.6 7.7 0.4 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glycos_transf_2 PF00535.26 KER28468.1 - 5.2e-32 111.0 0.0 2.4e-31 108.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KER28468.1 - 6.3e-21 75.0 1.7 3.7e-17 62.8 1.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KER28468.1 - 1.6e-05 24.5 0.0 3.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KER28468.1 - 0.0016 18.4 0.0 0.0051 16.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF4058 PF13267.6 KER28468.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Ricin_B_lectin PF00652.22 KER28470.1 - 1.5e-12 47.9 0.0 2.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 KER28471.1 - 3.6e-23 82.2 0.0 5.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Branch PF02485.21 KER28472.1 - 7.2e-48 163.3 0.5 2.4e-33 115.7 0.1 2.3 2 0 0 2 2 2 2 Core-2/I-Branching enzyme TPR_2 PF07719.17 KER28472.1 - 1.4e-06 28.0 5.2 0.22 11.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER28472.1 - 1.7e-05 25.0 4.4 0.00088 19.5 0.7 2.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER28472.1 - 3e-05 23.6 1.9 0.77 9.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER28472.1 - 0.00084 19.4 0.6 2 8.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER28472.1 - 0.0019 18.0 0.9 3.1 7.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER28472.1 - 0.045 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KER28472.1 - 4.2 7.6 5.2 30 4.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MH2 PF03166.14 KER28473.1 - 2e-66 223.8 0.1 4.4e-66 222.6 0.1 1.6 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 KER28473.1 - 0.00031 20.6 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 CBP PF12192.8 KER28473.1 - 6.6 7.0 12.0 0.19 11.9 0.9 2.7 3 0 0 3 3 3 0 Fungal calcium binding protein PDZ PF00595.24 KER28474.1 - 5.3e-21 74.8 0.0 1.2e-10 41.6 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KER28474.1 - 2.5e-16 59.3 1.2 6.2e-07 29.2 0.2 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER28474.1 - 1.3e-08 35.1 0.0 0.00088 19.5 0.0 2.9 2 0 0 2 2 2 2 PDZ domain Par3_HAL_N_term PF12053.8 KER28474.1 - 4.1e-07 30.1 1.3 9.4e-07 29.0 1.3 1.6 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Branch PF02485.21 KER28477.1 - 1.4e-31 109.9 0.0 2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Branch PF02485.21 KER28478.1 - 3.8e-26 92.1 0.0 5.4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Sec31 PF11549.8 KER28478.1 - 0.093 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein transport protein SEC31 Pilus_CpaD PF09476.10 KER28480.1 - 0.0026 17.5 0.1 0.48 10.1 0.0 2.0 1 1 1 2 2 2 2 Pilus biogenesis CpaD protein (pilus_cpaD) PCI PF01399.27 KER28480.1 - 0.014 15.9 0.3 7 7.2 0.0 2.2 1 1 1 2 2 2 0 PCI domain DUF4362 PF14275.6 KER28480.1 - 0.12 12.7 0.0 21 5.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4362) DUF1759 PF03564.15 KER28486.1 - 1.7e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) HSP20 PF00011.21 KER28486.1 - 0.00028 21.0 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ldl_recept_a PF00057.18 KER28487.1 - 0.00022 21.4 7.9 0.00049 20.3 7.9 1.6 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Cullin PF00888.22 KER28487.1 - 0.093 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Cullin family Ras PF00071.22 KER28490.1 - 2.3e-49 167.1 0.0 5.3e-49 165.9 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER28490.1 - 5.1e-31 107.4 0.0 9.8e-31 106.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER28490.1 - 8.5e-10 38.4 0.0 5.7e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER28490.1 - 3.1e-05 24.0 0.0 0.036 14.0 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KER28490.1 - 0.0004 20.0 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER28490.1 - 0.00055 19.4 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER28490.1 - 0.0009 19.3 0.0 0.0037 17.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KER28490.1 - 0.0085 16.5 0.0 0.0095 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KER28490.1 - 0.012 15.9 0.0 0.038 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KER28490.1 - 0.026 14.2 0.2 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KER28490.1 - 0.15 11.7 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KER28490.1 - 0.17 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin Hpr_kinase_C PF07475.12 KER28490.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RRM_1 PF00076.22 KER28491.1 - 6.7e-38 128.4 0.1 3.2e-18 65.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER28491.1 - 0.0062 16.6 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 KER28491.1 - 0.011 15.3 0.0 0.61 9.7 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER28491.1 - 0.084 13.0 0.0 22 5.3 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif NOP5NT PF08156.13 KER28491.1 - 0.085 13.3 1.1 10 6.6 0.0 3.1 3 0 0 3 3 3 0 NOP5NT (NUC127) domain PHM7_cyt PF14703.6 KER28491.1 - 4.4 7.5 5.3 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 KER28495.1 - 1.5e-07 31.1 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER28495.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Inositol_P PF00459.25 KER28497.1 - 1.6e-27 96.7 0.0 2.6e-24 86.2 0.0 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family NADH5_C PF06455.11 KER28497.1 - 0.036 13.6 0.1 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Nt_Gln_amidase PF09764.9 KER28500.1 - 4.3e-53 179.7 0.2 5.6e-53 179.3 0.2 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase Gln_deamidase_2 PF18626.1 KER28500.1 - 0.072 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Glutaminase hEGF PF12661.7 KER28501.1 - 0.47 11.2 19.5 0.65 10.7 0.7 5.2 4 0 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.27 KER28501.1 - 0.9 9.9 27.3 1.7 9.0 0.2 5.5 5 0 0 5 5 5 0 EGF-like domain zf-C2HC_2 PF13913.6 KER28502.1 - 4.1e-10 39.3 10.4 6.2e-05 22.8 1.1 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 KER28502.1 - 0.0023 17.6 3.2 0.0023 17.6 3.2 3.2 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.7 KER28502.1 - 0.023 14.7 1.0 0.023 14.7 1.0 3.6 4 0 0 4 4 4 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 KER28502.1 - 1.9 8.7 6.7 0.26 11.5 1.1 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 KER28502.1 - 3.6 8.4 10.9 0.1 13.3 0.9 3.3 4 0 0 4 4 4 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KER28502.1 - 7.2 6.2 10.8 0.22 11.0 0.8 3.4 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 KER28502.1 - 8.3 6.5 7.6 2.6 8.1 0.6 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TRAP-delta PF05404.12 KER28503.1 - 0.072 12.6 0.1 0.71 9.4 0.1 2.3 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) E1_DerP2_DerF2 PF02221.15 KER28505.1 - 1.5e-05 25.4 0.0 1.9e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 ML domain E1_DerP2_DerF2 PF02221.15 KER28506.1 - 6.3e-18 65.5 0.2 7.5e-18 65.2 0.2 1.1 1 0 0 1 1 1 1 ML domain DUF2706 PF10913.8 KER28506.1 - 0.0053 16.6 1.1 0.011 15.6 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2706) Globin PF00042.22 KER28507.1 - 3.3e-15 56.6 0.0 9e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Globin DUF1931 PF09123.11 KER28507.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) RXLR PF16810.5 KER28508.1 - 0.021 15.2 0.0 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF3331 PF11811.8 KER28509.1 - 0.0082 16.0 0.1 5.7 6.9 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3331) DUF1850 PF08905.11 KER28510.1 - 0.019 15.3 0.0 9.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1850) fn3 PF00041.21 KER28511.1 - 0.028 14.8 0.2 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 Fibronectin type III domain ORF6C PF10552.9 KER28513.1 - 0.064 13.3 0.6 0.19 11.8 0.6 1.7 1 0 0 1 1 1 0 ORF6C domain RA PF00788.23 KER28514.1 - 2.6e-23 82.5 0.2 4.5e-11 43.2 0.0 2.8 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 KER28514.1 - 3.3e-21 75.5 3.0 7.4e-21 74.4 3.0 1.6 1 0 0 1 1 1 1 DIL domain PDZ PF00595.24 KER28514.1 - 5.6e-12 45.8 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER28514.1 - 0.00061 19.6 0.4 0.0019 18.0 0.4 1.9 1 0 0 1 1 1 1 PDZ domain MMR_HSR1 PF01926.23 KER28515.1 - 1.3e-15 57.4 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 KER28515.1 - 7.4e-15 54.9 0.4 3.3e-14 52.8 0.4 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 KER28515.1 - 3.9e-10 39.5 0.0 6.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KER28515.1 - 0.048 13.1 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 KER28515.1 - 0.11 11.9 0.0 3.3 7.1 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family INTS5_C PF14838.6 KER28517.1 - 3.6e-05 22.6 1.7 9.7e-05 21.2 1.7 1.6 1 1 0 1 1 1 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 KER28517.1 - 5.5e-05 22.9 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus RVT_1 PF00078.27 KER28519.1 - 1.1e-15 57.8 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2353 PF09789.9 KER28520.1 - 0.0091 15.4 1.0 0.012 15.0 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 KER28520.1 - 0.017 14.0 1.7 0.023 13.6 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4337 PF14235.6 KER28520.1 - 0.037 14.1 0.2 0.061 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GreA_GreB_N PF03449.15 KER28520.1 - 0.074 13.2 2.4 0.13 12.4 1.6 1.8 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal CENP-H PF05837.12 KER28520.1 - 0.16 12.4 4.9 0.27 11.7 4.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) PDZ PF00595.24 KER28521.1 - 2.6e-07 30.9 0.0 7e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KER28521.1 - 0.00025 20.8 0.2 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KER28522.1 - 2.5e-110 361.0 0.0 6.4e-12 45.7 0.1 12.8 12 1 1 13 13 13 11 PDZ domain PDZ_6 PF17820.1 KER28522.1 - 3e-79 260.8 26.1 6.2e-12 45.2 0.1 12.4 13 0 0 13 13 13 11 PDZ domain PDZ_2 PF13180.6 KER28522.1 - 2.9e-49 165.3 0.4 4.5e-05 23.7 0.0 11.9 11 1 1 12 12 12 10 PDZ domain DUF11 PF01345.18 KER28522.1 - 0.0015 18.7 2.9 2.6 8.4 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function DUF11 Thioredoxin_12 PF18400.1 KER28523.1 - 0.008 16.0 0.1 0.0083 16.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Syja_N PF02383.18 KER28525.1 - 2.2e-30 106.1 0.6 1.3e-23 83.8 0.0 2.2 1 1 1 2 2 2 2 SacI homology domain TUG-UBL1 PF11470.8 KER28526.1 - 6.7e-13 48.7 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KER28526.1 - 1.9e-07 31.1 0.4 8.3e-07 29.1 0.0 2.3 3 0 0 3 3 3 1 UBX domain RBD PF02196.15 KER28526.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain Evr1_Alr PF04777.13 KER28527.1 - 3.5e-25 88.4 0.1 9.3e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Y_phosphatase PF00102.27 KER28529.1 - 2.3e-48 164.8 0.0 6.9e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KER28529.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER28529.1 - 0.026 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family MitoNEET_N PF10660.9 KER28529.1 - 0.059 13.4 0.2 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3751 PF12571.8 KER28529.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage tail-collar fibre protein PTPlike_phytase PF14566.6 KER28529.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1759 PF03564.15 KER28533.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RXT2_N PF08595.11 KER28534.1 - 0.26 11.3 2.5 0.47 10.5 2.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KER28534.1 - 1.1 8.6 15.4 2.1 7.6 15.4 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KER28534.1 - 2.5 6.3 5.0 3.4 5.8 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER28534.1 - 5.3 5.1 6.3 6.2 4.9 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family PSI_integrin PF17205.3 KER28535.1 - 0.012 15.4 2.1 0.03 14.0 2.1 1.8 1 0 0 1 1 1 0 Integrin plexin domain RSB_motif PF16294.5 KER28537.1 - 1.3e-18 67.1 6.2 1.3e-18 67.1 6.2 6.5 4 1 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 KER28537.1 - 2.1e-08 33.7 1.1 6.3e-08 32.2 0.5 2.1 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 KER28537.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-1_beta_acid PF10587.9 KER28537.1 - 0.14 12.6 6.7 0.26 11.8 6.7 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF2880 PF11082.8 KER28539.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Trypsin PF00089.26 KER28540.1 - 1.4e-33 116.6 0.1 1.3e-32 113.4 0.1 2.4 1 1 0 1 1 1 1 Trypsin Pho86 PF11124.8 KER28542.1 - 0.79 9.1 18.4 0.94 8.9 18.4 1.0 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF898 PF05987.13 KER28542.1 - 1.3 8.0 27.2 1.4 7.9 27.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF373 PF04123.13 KER28542.1 - 3.6 6.9 16.1 4.1 6.7 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Biopterin_H PF00351.21 KER28544.1 - 3.5e-172 572.0 0.0 4.2e-172 571.7 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 KER28544.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 ACT domain ANTH PF07651.16 KER28546.1 - 1.8e-16 60.0 1.2 3.7e-16 59.0 1.2 1.6 1 1 0 1 1 1 1 ANTH domain TFIIS_M PF07500.14 KER28548.1 - 0.11 12.9 0.1 0.15 12.5 0.1 1.2 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Phosducin PF02114.16 KER28549.1 - 7.4e-11 41.5 0.0 9e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Phosducin Nefa_Nip30_N PF10187.9 KER28549.1 - 0.0023 18.2 0.7 0.0044 17.3 0.7 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 EPL1 PF10513.9 KER28549.1 - 0.079 13.3 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like ASFV_L11L PF05293.11 KER28550.1 - 0.16 12.3 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein PHD PF00628.29 KER28552.1 - 4.9e-05 23.1 3.2 0.00014 21.7 1.5 2.3 2 0 0 2 2 2 1 PHD-finger DUF4199 PF13858.6 KER28555.1 - 0.11 12.9 4.4 0.17 12.3 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Rep_fac-A_C PF08646.10 KER28555.1 - 2.3 8.0 4.6 27 4.5 1.5 2.5 2 1 1 3 3 3 0 Replication factor-A C terminal domain OATP PF03137.20 KER28555.1 - 5.8 5.1 10.4 2.1 6.5 2.6 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Miff PF05644.11 KER28556.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff PAP_assoc PF03828.19 KER28557.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Antibiotic_NAT PF02522.14 KER28557.1 - 0.17 11.7 0.9 6.2 6.6 0.2 2.4 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase CAF1C_H4-bd PF12265.8 KER28558.1 - 0.0002 21.5 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GpcrRhopsn4 PF10192.9 KER28559.1 - 4.8e-24 85.2 16.3 6.9e-24 84.6 16.3 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 KER28559.1 - 0.0011 18.3 7.6 0.0018 17.6 7.6 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor SabA_adhesion PF18304.1 KER28559.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain EF-hand_1 PF00036.32 KER28561.1 - 2.9e-30 101.5 10.6 6e-07 28.6 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER28561.1 - 7.2e-29 100.1 4.2 5.5e-16 58.8 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER28561.1 - 1.3e-22 78.2 5.6 6.6e-05 22.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KER28561.1 - 2.6e-22 76.8 9.2 1.1e-06 28.1 0.1 5.2 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 KER28561.1 - 4.1e-22 77.8 12.6 1.3e-13 50.5 1.9 4.0 2 2 3 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KER28561.1 - 4.1e-09 36.8 0.3 0.0011 19.3 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER28561.1 - 1.5e-06 28.1 1.9 0.041 13.8 0.1 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER28561.1 - 0.00022 21.4 4.0 0.92 9.7 0.1 3.8 2 2 2 4 4 4 2 Dockerin type I domain EF-hand_9 PF14658.6 KER28561.1 - 0.0011 19.3 0.3 0.033 14.5 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain TerB PF05099.13 KER28561.1 - 0.0015 18.5 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KER28561.1 - 0.0064 16.4 0.6 0.28 11.1 0.0 2.8 2 2 0 2 2 2 1 Caleosin related protein VCBS PF13517.6 KER28561.1 - 0.041 14.5 3.1 1.2 9.8 0.9 3.1 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4953 PF16313.5 KER28561.1 - 0.086 12.0 0.0 0.49 9.5 0.0 1.8 1 1 1 2 2 2 0 Met-zincin GIY-YIG PF01541.24 KER28562.1 - 0.00011 22.4 0.7 0.00025 21.3 0.7 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain EF-hand_1 PF00036.32 KER28563.1 - 3.3e-13 48.1 3.3 1.7e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER28563.1 - 3e-10 39.1 1.2 6.9e-06 25.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KER28563.1 - 1.1e-09 38.6 1.0 2.6e-09 37.4 0.5 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KER28563.1 - 2.4e-09 36.9 6.9 2.1e-07 30.7 1.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER28563.1 - 1.2e-07 31.0 0.9 0.00013 21.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain Enkurin PF13864.6 KER28565.1 - 2.6e-20 72.7 2.3 2.6e-20 72.7 2.3 2.0 2 0 0 2 2 2 1 Calmodulin-binding Nuc_sug_transp PF04142.15 KER28567.1 - 1.1e-31 110.2 13.2 1e-30 107.0 10.0 2.6 2 1 0 2 2 2 1 Nucleotide-sugar transporter Pepdidase_M14_N PF18027.1 KER28567.1 - 8.9e-14 51.8 0.6 2.5e-13 50.3 0.6 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 KER28567.1 - 6.5e-12 45.8 0.0 1.9e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase HC2 PF07382.11 KER28567.1 - 0.00034 20.7 3.2 0.41 10.7 0.3 2.5 2 0 0 2 2 2 2 Histone H1-like nucleoprotein HC2 SLC35F PF06027.12 KER28567.1 - 0.054 13.0 17.6 0.68 9.4 12.4 2.2 2 0 0 2 2 2 0 Solute carrier family 35 NOA36 PF06524.12 KER28567.1 - 0.58 9.4 2.7 1.1 8.5 2.7 1.4 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 KER28569.1 - 1.4e-17 63.2 0.3 2.7e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER28569.1 - 4e-05 23.7 0.4 0.00048 20.2 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 KER28569.1 - 0.027 14.5 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif C1_1 PF00130.22 KER28575.1 - 1.4e-21 76.1 25.5 1.2e-11 44.3 4.9 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_3 PF13922.6 KER28575.1 - 0.00082 19.7 8.5 0.29 11.5 1.2 2.8 2 0 0 2 2 2 2 PHD domain of transcriptional enhancer, Asx AMMECR1 PF01871.17 KER28575.1 - 0.011 15.4 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 AMMECR1 PhnH PF05845.12 KER28575.1 - 0.023 14.5 0.1 11 5.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial phosphonate metabolism protein (PhnH) OrfB_Zn_ribbon PF07282.11 KER28575.1 - 1.6 8.7 9.3 11 6.0 1.4 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Membr_traf_MHD PF10540.9 KER28576.1 - 1.1e-44 152.2 1.0 1.5e-42 145.3 0.2 2.5 2 0 0 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KER28576.1 - 5.5e-39 132.6 0.2 1e-24 86.8 0.2 2.6 2 0 0 2 2 2 2 C2 domain DUF1041 PF06292.17 KER28576.1 - 1.4e-31 109.0 0.0 2.2e-30 105.2 0.0 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) DUF4795 PF16043.5 KER28576.1 - 0.058 13.0 0.5 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CEP76-C2 PF15627.6 KER28576.1 - 0.084 12.4 0.0 8.6 5.9 0.0 2.8 3 0 0 3 3 3 0 CEP76 C2 domain Nop14 PF04147.12 KER28577.1 - 0.0025 16.1 6.6 0.0025 16.1 6.6 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KER28577.1 - 0.021 13.1 4.4 0.019 13.3 4.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KER28577.1 - 0.052 12.0 4.5 0.049 12.1 4.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 KER28577.1 - 0.1 10.7 26.3 0.12 10.4 26.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KER28577.1 - 0.19 10.8 24.9 0.22 10.6 24.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cnd2 PF05786.14 KER28577.1 - 3.9 6.0 13.6 3.8 6.0 13.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CNDH2_C PF16858.5 KER28577.1 - 6.3 6.6 7.9 6.3 6.6 7.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term COPI_C PF06957.11 KER28577.1 - 10 4.8 8.1 11 4.6 8.1 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus YacG PF03884.14 KER28578.1 - 0.0068 16.1 1.5 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 DNA gyrase inhibitor YacG Iso_dh PF00180.20 KER28580.1 - 8.8e-97 324.4 0.0 1.2e-96 323.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SOCS_box PF07525.16 KER28580.1 - 3.8e-05 23.9 1.8 7.8e-05 23.0 1.8 1.5 1 0 0 1 1 1 1 SOCS box Pkinase PF00069.25 KER28583.1 - 1.7e-15 57.1 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KER28583.1 - 1e-07 31.1 0.1 1.4e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KER28583.1 - 2.6e-05 23.6 0.0 3.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Clathrin_propel PF01394.20 KER28585.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Clathrin propeller repeat COesterase PF00135.28 KER28586.1 - 2.4e-32 112.5 0.0 9.1e-32 110.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family WD40 PF00400.32 KER28588.1 - 1.7e-11 44.4 0.8 0.00065 20.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28588.1 - 7.4e-08 32.6 0.0 0.00026 21.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4732 PF15876.5 KER28592.1 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) Pkinase_Tyr PF07714.17 KER28594.1 - 1.7e-79 266.8 0.0 4.1e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER28594.1 - 1.2e-38 133.0 0.0 1.8e-26 93.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.24 KER28594.1 - 2.5e-12 46.7 0.0 4.9e-11 42.6 0.0 2.7 1 1 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KER28594.1 - 8.9e-09 34.8 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER28594.1 - 3.1e-06 26.9 0.0 1.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Pkinase_fungal PF17667.1 KER28594.1 - 0.00089 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SH3_2 PF07653.17 KER28594.1 - 0.0058 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 KER28594.1 - 0.015 14.6 0.0 3.5 6.9 0.0 2.5 3 0 0 3 3 3 0 Kinase-like CTK3_C PF12350.8 KER28594.1 - 0.02 15.0 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus APH PF01636.23 KER28594.1 - 0.036 14.0 0.0 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Atg14 PF10186.9 KER28596.1 - 0.0032 16.6 3.2 0.0034 16.5 3.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4H2 PF10146.9 KER28596.1 - 0.011 16.0 0.5 0.015 15.6 0.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein FliJ PF02050.16 KER28596.1 - 0.15 12.3 7.0 0.18 12.0 5.9 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 KER28596.1 - 0.17 11.4 2.1 0.23 11.0 2.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 KER28596.1 - 0.23 10.8 4.3 0.3 10.4 4.3 1.2 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 KER28596.1 - 0.48 10.6 4.7 0.47 10.6 1.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RT_RNaseH PF17917.1 KER28597.1 - 5.6e-21 74.8 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER28597.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DHHC PF01529.20 KER28600.1 - 1.9e-37 128.4 9.4 1.9e-37 128.4 9.4 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Frag1 PF10277.9 KER28600.1 - 0.0046 16.5 1.0 0.0046 16.5 1.0 1.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Renin_r PF07850.14 KER28600.1 - 0.044 14.4 3.5 0.34 11.6 0.0 3.0 2 1 1 3 3 3 0 Renin receptor-like protein DUF1345 PF07077.11 KER28600.1 - 0.4 10.4 3.9 0.12 12.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF898 PF05987.13 KER28600.1 - 0.86 8.6 5.6 0.17 10.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) zf-A20 PF01754.16 KER28602.1 - 4.2e-12 45.8 8.9 4.2e-12 45.8 8.9 2.6 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.16 KER28602.1 - 1.2e-06 28.6 11.4 1.2e-06 28.6 11.4 2.3 2 1 0 2 2 2 1 AN1-like Zinc finger Ig_3 PF13927.6 KER28603.1 - 2.6e-12 47.2 0.0 3.4e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER28603.1 - 2.5e-10 40.3 0.0 1.6e-05 24.8 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KER28603.1 - 6e-09 36.0 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER28603.1 - 8.7e-09 35.5 0.0 0.00077 19.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KER28603.1 - 2.2e-05 24.7 0.2 0.0048 17.2 0.1 3.3 3 1 0 3 3 3 1 Immunoglobulin domain Ig_6 PF18452.1 KER28603.1 - 0.00021 20.8 0.0 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER28603.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KER28604.1 - 1.2e-10 41.8 0.2 7.7e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER28604.1 - 3.8e-09 36.5 0.0 0.00042 20.3 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 KER28604.1 - 2.6e-06 27.5 0.3 0.00015 21.9 0.1 3.0 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KER28604.1 - 1.5e-05 25.1 0.1 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KER28604.1 - 0.0014 18.9 0.1 0.81 10.1 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ras PF00071.22 KER28606.1 - 9.3e-20 70.8 0.0 1.1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER28606.1 - 8.1e-18 64.8 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER28606.1 - 0.0089 15.5 0.0 0.014 14.9 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER28606.1 - 0.018 15.1 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 KER28606.1 - 0.035 13.4 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.12 KER28606.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region GAF_2 PF13185.6 KER28607.1 - 6.1e-08 33.1 0.0 7.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KER28607.1 - 8.1e-05 23.3 0.0 0.00012 22.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain SspK PF08176.12 KER28607.1 - 0.017 15.3 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein K family zf-MYND PF01753.18 KER28608.1 - 1.7e-09 37.6 18.3 4.2e-09 36.4 18.3 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KER28608.1 - 0.34 10.8 7.9 0.73 9.8 7.9 1.6 1 0 0 1 1 1 0 HIT zinc finger DcpS_C PF11969.8 KER28609.1 - 2.8e-22 79.3 0.0 6.1e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KER28609.1 - 2.3e-11 44.4 0.0 7.6e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Forkhead PF00250.18 KER28610.1 - 7.9e-34 115.8 0.0 1.9e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain AATF-Che1 PF13339.6 KER28612.1 - 0.068 13.8 1.8 0.13 12.9 0.3 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CCDC24 PF15669.5 KER28612.1 - 4 7.3 11.1 5.1 6.9 0.0 3.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family Myb_DNA-bind_5 PF13873.6 KER28613.1 - 2.1e-09 37.3 2.9 6.6e-09 35.7 2.9 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KER28613.1 - 0.0078 16.6 0.6 0.019 15.3 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KER28615.1 - 0.0029 17.8 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3452 PF11934.8 KER28615.1 - 0.029 13.9 1.0 8.1 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) MMACHC PF16690.5 KER28615.1 - 0.043 13.4 0.9 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type C family DUF4256 PF14066.6 KER28615.1 - 0.13 12.0 2.1 10 5.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) BIR PF00653.21 KER28618.1 - 1.7e-11 44.6 0.0 2.7e-10 40.7 0.0 2.9 4 0 0 4 4 4 1 Inhibitor of Apoptosis domain CNDH2_N PF06278.11 KER28618.1 - 0.042 14.0 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal D_CNTX PF17492.2 KER28618.1 - 0.85 9.9 5.5 1.7 8.9 5.5 1.5 1 0 0 1 1 1 0 Delta Ctenitoxins GLTP PF08718.11 KER28620.1 - 1.4e-35 122.8 0.0 1.8e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) RRM_1 PF00076.22 KER28621.1 - 7.3e-16 57.7 0.2 2.4e-05 24.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KER28621.1 - 0.017 15.2 0.1 5.7 7.1 0.0 3.1 2 1 0 2 2 2 0 Limkain b1 EF-hand_2 PF09068.11 KER28622.1 - 3.9e-29 101.3 0.0 3.3e-28 98.3 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.11 KER28622.1 - 3.8e-26 91.3 0.0 1.8e-25 89.2 0.0 2.3 1 0 0 1 1 1 1 EF-hand Spectrin PF00435.21 KER28622.1 - 6.1e-06 26.7 2.8 6.1e-06 26.7 2.8 23.1 21 6 3 24 24 24 3 Spectrin repeat Fe_bilin_red PF05996.12 KER28622.1 - 0.048 13.3 3.6 4.8 6.8 0.9 4.3 4 0 0 4 4 4 0 Ferredoxin-dependent bilin reductase Imm7 PF15585.6 KER28622.1 - 0.067 13.5 0.3 8.6 6.7 0.1 3.9 3 0 0 3 3 3 0 Immunity protein 7 DUF4148 PF13663.6 KER28622.1 - 0.87 9.8 2.9 7.5 6.8 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) RNA_pol_Rpb1_5 PF04998.17 KER28623.1 - 2.9e-88 295.7 0.0 1.3e-84 283.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KER28623.1 - 1.7e-38 132.5 0.3 1.6e-18 67.5 0.0 3.5 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KER28623.1 - 1.8e-31 109.2 0.0 3.4e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KER28623.1 - 4.4e-30 103.8 0.0 9.6e-30 102.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 KER28623.1 - 8.2e-30 104.2 0.6 3.8e-20 72.4 0.2 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 DUF4258 PF14076.6 KER28623.1 - 0.0068 16.8 0.2 13 6.2 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4258) Amidohydro_1 PF01979.20 KER28623.1 - 0.075 12.3 0.1 5.8 6.1 0.0 2.3 1 1 1 2 2 2 0 Amidohydrolase family V-set PF07686.17 KER28624.1 - 0.00055 20.1 0.0 0.0074 16.4 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 KER28624.1 - 0.023 14.8 0.1 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_3 PF13927.6 KER28624.1 - 0.033 14.8 0.0 0.28 11.8 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain FlhC PF05280.11 KER28625.1 - 0.051 13.3 0.9 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) RRM_1 PF00076.22 KER28627.1 - 9e-24 83.1 0.8 2.1e-12 46.7 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER28627.1 - 5.8e-06 26.3 0.1 0.00017 21.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KER28627.1 - 0.012 15.6 0.4 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif C2 PF00168.30 KER28628.1 - 4.7e-11 42.9 0.0 7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain CUE PF02845.16 KER28628.1 - 8.3e-07 28.6 0.1 1.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain IRF-2BP1_2 PF11261.8 KER28628.1 - 0.078 12.6 0.4 0.21 11.2 0.4 1.7 1 1 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Spem1 PF15670.5 KER28629.1 - 0.29 10.7 4.7 0.33 10.5 4.7 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 MPM1 PF17234.2 KER28629.1 - 0.9 9.8 4.7 1.1 9.5 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4200 PF13863.6 KER28630.1 - 6.6e-08 33.0 0.5 6.6e-08 33.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) SIKE PF05769.11 KER28630.1 - 0.027 14.4 0.5 0.038 13.9 0.5 1.2 1 0 0 1 1 1 0 SIKE family DUF4200 PF13863.6 KER28631.1 - 4.6e-15 56.1 2.4 4.6e-15 56.1 2.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) TraE PF05309.11 KER28631.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 TraE protein Peptidase_S51 PF03575.17 KER28631.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 SWIM PF04434.17 KER28633.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.3 1 1 0 1 1 1 0 SWIM zinc finger Ribosomal_L3 PF00297.22 KER28636.1 - 7.2e-164 545.1 12.0 1.8e-163 543.8 12.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L3 Ceramidase_alk PF04734.13 KER28637.1 - 1.7e-220 733.0 0.0 2e-220 732.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KER28637.1 - 2.6e-47 160.8 0.1 4.6e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF1794 PF08768.11 KER28637.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) Exo_endo_phos PF03372.23 KER28638.1 - 3e-24 85.8 0.6 4e-24 85.4 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NRDE-2 PF08424.10 KER28639.1 - 5.8e-69 232.7 0.3 4e-68 229.9 0.0 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference zf-C2H2 PF00096.26 KER28641.1 - 3.6e-17 61.8 50.2 0.01 16.2 0.3 8.1 8 1 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER28641.1 - 1.6e-10 40.9 53.0 0.025 15.4 0.4 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger FOXP-CC PF16159.5 KER28641.1 - 1.1e-08 35.6 28.3 1.2 9.8 0.1 7.7 4 1 4 8 8 8 6 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KER28641.1 - 8.9e-05 22.7 45.4 0.0039 17.6 0.4 7.6 7 0 0 7 7 7 4 Zinc-finger double domain zf-TRAF PF02176.18 KER28641.1 - 0.0024 18.5 30.2 0.11 13.2 1.6 4.8 4 1 0 4 4 4 3 TRAF-type zinc finger zf-H2C2_5 PF13909.6 KER28641.1 - 0.12 12.2 0.2 0.12 12.2 0.2 7.0 8 1 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KER28641.1 - 1.2 9.5 11.4 16 5.9 0.1 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding TPR_2 PF07719.17 KER28642.1 - 3e-30 101.9 17.0 0.00014 21.7 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KER28642.1 - 1.1e-29 100.1 7.4 0.00076 19.5 0.1 9.2 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KER28642.1 - 5.8e-28 95.5 20.3 1.9e-06 27.4 0.0 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat DUF1736 PF08409.11 KER28642.1 - 7.6e-26 89.9 0.3 2.1e-25 88.5 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 KER28642.1 - 1.7e-25 87.5 12.1 0.0063 16.8 0.0 10.5 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KER28642.1 - 2.8e-25 88.7 12.8 3.9e-07 30.6 0.0 7.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 KER28642.1 - 4.3e-24 83.1 11.5 0.014 16.2 0.0 10.1 3 3 7 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KER28642.1 - 6.5e-23 81.0 14.9 4.7e-05 23.8 2.1 7.9 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KER28642.1 - 1.1e-21 76.3 11.9 1.2e-07 31.3 0.0 8.8 5 4 4 9 9 9 5 TPR repeat TPR_12 PF13424.6 KER28642.1 - 1.9e-20 72.9 13.2 0.00032 20.9 0.0 6.6 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 KER28642.1 - 8e-11 41.9 3.4 0.3 11.2 0.0 4.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KER28642.1 - 1.1e-09 37.6 12.8 0.18 11.9 0.0 8.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KER28642.1 - 5.9e-09 36.0 6.8 0.013 16.1 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KER28642.1 - 1.8e-08 33.9 3.2 0.022 14.0 0.5 3.6 2 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KER28642.1 - 1.3e-07 31.7 3.0 0.95 9.7 0.0 4.6 4 2 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KER28642.1 - 0.00015 22.1 3.2 0.74 10.2 0.7 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KER28642.1 - 0.00051 20.4 2.0 11 6.9 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KER28642.1 - 0.0024 17.7 26.3 0.13 12.1 0.1 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat PMT_2 PF13231.6 KER28642.1 - 0.0035 17.6 8.2 0.0035 17.6 8.2 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FAT PF02259.23 KER28642.1 - 0.018 14.3 0.0 0.33 10.1 0.0 2.6 1 1 2 3 3 3 0 FAT domain Coatomer_E PF04733.14 KER28642.1 - 0.029 13.8 1.2 1 8.7 0.0 2.7 3 0 0 3 3 3 0 Coatomer epsilon subunit TOM20_plant PF06552.12 KER28642.1 - 0.035 13.9 0.1 4.7 6.9 0.0 3.4 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF630 PF04783.12 KER28642.1 - 0.051 13.8 0.2 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Fe-S_assembly PF04384.13 KER28642.1 - 0.074 13.7 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Iron-sulphur cluster assembly TPR_5 PF12688.7 KER28642.1 - 0.1 12.8 0.6 6.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_21 PF09976.9 KER28642.1 - 0.37 10.5 1.7 0.67 9.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 KER28642.1 - 0.66 10.0 3.2 4.3 7.4 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.20 KER28644.1 - 2.3e-136 455.3 0.0 2.8e-136 455.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KER28644.1 - 0.007 15.5 0.0 0.69 8.9 0.0 2.9 2 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 LrgB PF04172.16 KER28645.1 - 0.051 13.1 5.1 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 LrgB-like family Laminin_N PF00055.17 KER28647.1 - 1.5e-48 165.4 0.0 2.1e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KER28647.1 - 2.6e-07 30.7 9.4 2.6e-07 30.7 9.4 2.8 2 1 0 2 2 2 1 Laminin EGF domain BNR_6 PF15899.5 KER28647.1 - 0.0078 16.2 1.6 0.012 15.6 0.2 2.1 2 0 0 2 2 2 1 BNR-Asp box repeat Thioredoxin_11 PF18078.1 KER28647.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain BNR PF02012.20 KER28647.1 - 0.15 12.1 2.3 0.25 11.5 0.1 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat DnaJ PF00226.31 KER28648.1 - 1.3e-12 47.6 0.5 1.9e-12 47.1 0.5 1.2 1 0 0 1 1 1 1 DnaJ domain CI-B14_5a PF07347.12 KER28649.1 - 1.5e-31 108.1 0.2 1.7e-31 108.0 0.2 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Cys_Met_Meta_PP PF01053.20 KER28652.1 - 5e-119 397.2 0.0 1.4e-95 320.1 0.0 3.0 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Exo_endo_phos_2 PF14529.6 KER28652.1 - 1.5e-05 24.8 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Aminotran_1_2 PF00155.21 KER28652.1 - 0.0014 17.9 0.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KER28652.1 - 0.016 14.2 0.1 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Met_gamma_lyase PF06838.11 KER28652.1 - 0.029 12.9 0.0 0.044 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase PAN_1 PF00024.26 KER28653.1 - 2.3e-05 24.3 1.0 6.8e-05 22.7 0.7 1.9 2 0 0 2 2 2 1 PAN domain Melibiase_2 PF16499.5 KER28653.1 - 0.058 12.5 0.6 0.18 10.9 0.2 1.8 2 0 0 2 2 2 0 Alpha galactosidase A Phage_Gp17 PF17549.2 KER28654.1 - 0.0013 18.8 1.7 0.37 10.8 0.1 2.3 1 1 1 2 2 2 2 Gene Product 17 RapA_C PF12137.8 KER28654.1 - 1 8.3 14.8 1.6 7.7 4.7 2.1 1 1 1 2 2 2 0 RNA polymerase recycling family C-terminal BAG PF02179.16 KER28654.1 - 1.6 9.2 7.6 41 4.7 7.6 2.3 1 1 0 1 1 1 0 BAG domain FlgN PF05130.12 KER28654.1 - 2.4 8.6 14.0 5.5 7.5 3.9 1.8 1 1 1 2 2 2 0 FlgN protein His_Phos_1 PF00300.22 KER28656.1 - 4.4e-17 62.4 0.0 8.7e-08 32.1 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Osteoregulin PF07175.11 KER28656.1 - 0.054 13.7 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Osteoregulin AtuA PF07287.11 KER28656.1 - 0.087 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA RCC1_2 PF13540.6 KER28656.1 - 0.24 11.3 1.0 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat SHIPPO-rpt PF07004.12 KER28657.1 - 2e-15 56.9 26.9 5.3e-05 23.9 0.5 6.4 7 1 0 7 7 7 5 Sperm-tail PG-rich repeat RVT_1 PF00078.27 KER28657.1 - 0.0042 16.6 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VWA_3 PF13768.6 KER28658.1 - 8.2e-28 97.3 0.0 1.4e-10 41.4 0.0 4.5 4 1 0 4 4 4 3 von Willebrand factor type A domain VWA PF00092.28 KER28658.1 - 4.9e-10 39.9 0.0 0.00086 19.6 0.0 4.1 3 1 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 KER28658.1 - 5.4e-10 39.9 0.0 0.00068 20.3 0.0 4.0 3 0 0 3 3 3 3 von Willebrand factor type A domain Guanylate_cyc PF00211.20 KER28659.1 - 2e-98 327.4 1.0 4.8e-55 186.0 0.3 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain zf-H2C2_2 PF13465.6 KER28660.1 - 1e-25 88.9 58.2 3.8e-07 30.2 0.5 8.4 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2 PF00096.26 KER28660.1 - 3.1e-21 74.6 40.0 0.0017 18.7 1.0 7.3 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KER28660.1 - 1.2e-15 57.3 15.4 0.0033 17.7 0.1 6.6 6 1 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KER28660.1 - 2.2e-15 56.0 50.5 0.0029 18.3 0.9 7.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER28660.1 - 9e-07 28.7 40.3 0.053 13.5 0.2 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KER28660.1 - 0.0027 18.0 23.5 0.24 11.9 0.3 6.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER28660.1 - 0.011 16.0 7.4 0.02 15.2 1.7 4.5 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.10 KER28660.1 - 0.3 11.8 3.7 0.84 10.4 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Pyr_redox_2 PF07992.14 KER28661.1 - 1.6e-05 24.3 0.0 6e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HSM3_C PF18794.1 KER28661.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain FMO-like PF00743.19 KER28661.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like PQQ PF01011.21 KER28662.1 - 0.076 13.0 0.1 8.3 6.5 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Rab5ip PF07019.12 KER28662.1 - 0.7 10.5 5.0 0.15 12.6 0.4 2.3 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Nop25 PF09805.9 KER28663.1 - 0.064 13.7 2.6 0.16 12.5 2.6 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) EF-hand_3 PF09069.11 KER28664.1 - 4.6e-13 49.4 0.0 1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 KER28664.1 - 5.4e-12 45.3 6.2 9.7e-12 44.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 KER28664.1 - 0.00077 19.7 6.2 0.0016 18.7 6.2 1.5 1 0 0 1 1 1 1 C1 domain zf-Nse PF11789.8 KER28664.1 - 0.029 14.2 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.15 KER28664.1 - 0.52 10.1 8.3 3.3 7.5 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 KER28664.1 - 5.9 7.2 7.9 15 5.8 0.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MerR-DNA-bind PF09278.11 KER28664.1 - 6.1 7.5 7.5 0.29 11.7 0.2 2.4 3 0 0 3 3 3 0 MerR, DNA binding EF-hand_2 PF09068.11 KER28665.1 - 7.6e-21 74.5 1.6 7.5e-20 71.3 1.6 2.0 1 1 0 1 1 1 1 EF hand PAN_1 PF00024.26 KER28668.1 - 0.0085 16.0 0.5 0.012 15.6 0.5 1.2 1 0 0 1 1 1 1 PAN domain WD40 PF00400.32 KER28669.1 - 2.4e-39 132.6 28.6 2.3e-07 31.4 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28669.1 - 5e-11 42.7 0.4 0.00057 20.1 0.1 4.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER28669.1 - 0.00051 19.5 0.0 0.03 13.7 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 KER28669.1 - 0.00087 18.0 1.3 0.45 9.1 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KER28669.1 - 0.04 12.4 0.2 2.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Resistin PF06954.11 KER28669.1 - 4.7 7.8 8.0 11 6.6 0.2 3.8 3 1 1 4 4 4 0 Resistin G-patch PF01585.23 KER28670.1 - 8e-10 38.5 3.2 0.00018 21.3 0.5 2.9 3 1 1 4 4 4 2 G-patch domain G-patch_2 PF12656.7 KER28670.1 - 0.035 14.2 0.3 0.49 10.5 0.3 2.3 1 1 0 1 1 1 0 G-patch domain MFS_1 PF07690.16 KER28671.1 - 3.2e-36 125.0 35.6 8.6e-22 77.5 8.5 4.0 3 1 1 4 4 4 4 Major Facilitator Superfamily DUF4820 PF16091.5 KER28671.1 - 0.047 13.1 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) VPDSG-CTERM PF18205.1 KER28671.1 - 3.5 7.5 7.5 27 4.7 0.1 3.4 2 0 0 2 2 2 0 VPDSG-CTERM motif EF-hand_4 PF12763.7 KER28672.1 - 5.3e-29 100.2 0.0 1.4e-15 57.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KER28672.1 - 4.9e-12 44.5 0.1 0.00068 19.0 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KER28672.1 - 9.5e-07 28.3 0.1 0.1 12.6 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KER28672.1 - 5e-06 26.9 0.0 0.087 13.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KER28672.1 - 0.002 17.5 3.5 0.85 9.2 0.2 2.9 3 0 0 3 3 3 2 EF hand ATG16 PF08614.11 KER28672.1 - 0.0053 17.0 18.5 0.0053 17.0 18.5 3.5 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) EF-hand_8 PF13833.6 KER28672.1 - 0.016 15.0 0.2 3.8 7.4 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair AAA_13 PF13166.6 KER28672.1 - 6.3 5.3 18.3 8.7 4.8 18.3 1.1 1 0 0 1 1 1 0 AAA domain Scramblase PF03803.15 KER28673.1 - 0.00031 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Scramblase Beta_elim_lyase PF01212.21 KER28673.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase EF-hand_1 PF00036.32 KER28675.1 - 3.3e-34 113.9 13.8 3.1e-07 29.4 0.6 6.4 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 KER28675.1 - 1.1e-31 106.0 11.5 1.3e-06 27.9 0.1 6.4 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 KER28675.1 - 1e-25 90.0 21.0 3.1e-11 43.5 1.1 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KER28675.1 - 1.6e-20 71.6 19.7 0.00018 20.9 0.4 6.4 6 0 0 6 6 6 6 EF hand EF-hand_8 PF13833.6 KER28675.1 - 3.2e-10 39.7 6.6 0.00098 18.9 0.1 5.1 5 1 0 5 5 5 3 EF-hand domain pair GPHH PF16905.5 KER28675.1 - 1.1e-06 28.3 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 Voltage-dependent L-type calcium channel, IQ-associated Dockerin_1 PF00404.18 KER28675.1 - 0.0039 17.3 0.4 0.48 10.6 0.0 3.6 4 0 0 4 4 4 1 Dockerin type I domain EF-hand_9 PF14658.6 KER28675.1 - 0.0058 16.9 0.0 0.51 10.7 0.0 3.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 KER28675.1 - 0.0076 16.1 9.9 1.2 9.0 0.1 4.8 5 0 0 5 5 5 1 EF hand UPF0149 PF03695.13 KER28675.1 - 0.011 16.1 2.7 0.82 9.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) NuiA PF07924.11 KER28675.1 - 0.076 13.4 0.6 2.9 8.3 0.1 2.9 3 0 0 3 3 3 0 Nuclease A inhibitor-like protein E2F_TDP PF02319.20 KER28675.1 - 0.12 12.5 0.1 25 5.0 0.0 2.5 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain p25-alpha PF05517.12 KER28675.1 - 0.34 11.1 2.3 5.3 7.2 0.0 2.9 3 2 0 3 3 3 0 p25-alpha Caleosin PF05042.13 KER28675.1 - 0.45 10.4 6.8 35 4.3 0.1 4.6 3 2 2 5 5 5 0 Caleosin related protein PALP PF00291.25 KER28676.1 - 3.4e-72 243.4 1.4 4.1e-72 243.1 1.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 KER28676.1 - 1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain rve PF00665.26 KER28677.1 - 0.0014 18.8 0.0 0.0019 18.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain BSD PF03909.17 KER28678.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 BSD domain Oxysterol_BP PF01237.18 KER28680.1 - 1.7e-77 260.8 0.0 2.9e-75 253.4 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 KER28680.1 - 3.8e-14 53.1 0.1 7.4e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KER28680.1 - 7.2e-08 32.6 0.5 1.5e-07 31.5 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KER28680.1 - 1.4e-05 25.4 3.7 0.00021 21.7 3.7 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KER28680.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 KER28680.1 - 0.0069 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KER28680.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 PH domain S_layer_N PF05123.12 KER28680.1 - 0.19 11.6 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 S-layer like family, N-terminal region OKR_DC_1_C PF03711.15 KER28681.1 - 0.13 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain PP2C PF00481.21 KER28682.1 - 7.6e-20 71.6 0.0 8.9e-17 61.6 0.0 3.1 3 1 0 3 3 3 2 Protein phosphatase 2C tRNA_m1G_MT PF01746.21 KER28683.1 - 7.2e-10 38.9 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RVT_1 PF00078.27 KER28683.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Furin-like PF00757.20 KER28684.1 - 5.6e-28 97.7 100.5 7.7e-16 58.3 29.5 5.1 2 1 3 5 5 5 5 Furin-like cysteine rich region GF_recep_IV PF14843.6 KER28684.1 - 1.1e-16 60.8 103.6 1.3e-06 28.2 6.9 7.5 3 2 3 7 7 7 5 Growth factor receptor domain IV Recep_L_domain PF01030.24 KER28684.1 - 7.7e-07 29.2 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Receptor L domain Pkinase_Tyr PF07714.17 KER28685.1 - 1.7e-74 250.4 0.1 1.7e-71 240.6 0.1 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KER28685.1 - 1.8e-32 112.7 0.0 1.4e-31 109.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KER28685.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KER28685.1 - 0.024 14.6 0.1 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KER28685.1 - 0.063 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER28685.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2_4 PF13894.6 KER28686.1 - 0.00085 20.0 34.7 0.078 13.9 2.5 5.1 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KER28686.1 - 0.026 15.0 27.6 0.13 12.8 2.5 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-FPG_IleRS PF06827.14 KER28686.1 - 0.058 13.3 2.8 0.27 11.2 0.5 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-C2H2_jaz PF12171.8 KER28686.1 - 0.94 9.9 3.8 14 6.1 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KER28686.1 - 3.6 7.3 8.6 0.27 10.9 2.5 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain ACP_PD PF04336.12 KER28688.1 - 0.085 13.3 0.5 0.16 12.4 0.5 1.5 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Laminin_II PF06009.12 KER28688.1 - 0.15 12.1 0.1 16 5.5 0.0 2.1 2 0 0 2 2 2 0 Laminin Domain II Kinesin PF00225.23 KER28689.1 - 2.2e-79 266.8 0.1 3.5e-78 262.9 0.1 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER28689.1 - 4.3e-46 156.6 0.0 1.3e-45 155.0 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding Holin_BhlA PF10960.8 KER28689.1 - 0.0036 17.3 2.9 0.011 15.6 0.3 2.5 2 0 0 2 2 2 1 BhlA holin family DUF4763 PF15960.5 KER28689.1 - 3.6 6.8 7.3 0.13 11.5 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DivIC PF04977.15 KER28689.1 - 5.3 6.9 6.0 0.91 9.3 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator RhoGAP PF00620.27 KER28690.1 - 3.3e-24 85.5 0.1 5.3e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 KER28690.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) DUF572 PF04502.13 KER28691.1 - 3e-74 250.6 0.2 5.4e-74 249.8 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) APG5 PF04106.12 KER28691.1 - 7.8e-57 192.5 1.5 3.5e-49 167.4 0.1 2.8 2 0 0 2 2 2 2 Autophagy protein Apg5 Exo_endo_phos_2 PF14529.6 KER28691.1 - 0.049 13.5 0.2 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Ras PF00071.22 KER28693.1 - 2.4e-19 69.5 0.1 1.7e-14 53.7 0.1 2.2 2 0 0 2 2 2 2 Ras family Arf PF00025.21 KER28693.1 - 6.5e-06 25.7 0.7 0.05 13.1 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER28693.1 - 3.6e-05 23.8 0.1 0.00011 22.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KER28693.1 - 6.2e-05 23.2 0.1 0.081 13.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KER28693.1 - 0.00022 20.8 0.2 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B SRPRB PF09439.10 KER28693.1 - 0.0025 17.3 0.8 0.51 9.7 0.0 2.6 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KER28693.1 - 0.007 16.9 0.2 0.019 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KER28693.1 - 0.027 14.9 0.7 0.71 10.3 0.7 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KER28693.1 - 0.038 13.7 0.0 0.081 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KER28693.1 - 0.075 12.6 0.1 8.5 5.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KER28693.1 - 0.16 11.7 0.3 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF226 PF02890.14 KER28694.1 - 0.011 15.8 0.1 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 Borrelia family of unknown function DUF226 ALIX_LYPXL_bnd PF13949.6 KER28694.1 - 2.7 7.2 15.2 0.8 8.9 10.3 2.5 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV UTP15_C PF09384.10 KER28695.1 - 5.2e-14 52.2 0.6 2.4e-13 50.0 0.6 1.9 1 1 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KER28695.1 - 4.6e-10 39.9 3.4 0.0017 19.1 0.4 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28695.1 - 1.3e-07 31.8 0.0 0.00047 20.4 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.11 KER28695.1 - 0.0036 17.2 0.3 0.0098 15.8 0.2 1.9 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.11 KER28695.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like DUF5466 PF17554.2 KER28695.1 - 0.1 12.8 1.0 0.34 11.1 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5466) WD40 PF00400.32 KER28698.1 - 2.1e-18 66.3 3.7 0.00083 20.1 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28698.1 - 0.0031 17.8 0.0 9.7 6.6 0.0 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain TMEM164 PF14808.6 KER28700.1 - 8.3e-63 212.1 2.6 1e-46 159.3 0.1 2.2 1 1 1 2 2 2 2 TMEM164 family zf-RING_12 PF17976.1 KER28700.1 - 0.018 15.3 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3959 PF13105.6 KER28700.1 - 0.16 11.5 0.7 0.27 10.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Vasohibin PF14822.6 KER28701.1 - 2.4e-72 243.1 0.3 3.1e-72 242.7 0.3 1.1 1 0 0 1 1 1 1 Vasohibin CLP_protease PF00574.23 KER28702.1 - 2.5e-52 177.4 0.0 4.8e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Clp protease CH PF00307.31 KER28702.1 - 4.9e-24 84.6 0.9 2.3e-11 43.9 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER28702.1 - 0.021 14.7 0.1 7.8 6.4 0.0 2.7 2 0 0 2 2 2 0 CAMSAP CH domain Med12-LCEWAV PF12145.8 KER28702.1 - 0.032 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain TPR_10 PF13374.6 KER28702.1 - 0.16 11.9 0.4 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ku PF02735.16 KER28704.1 - 9.3e-40 136.5 0.0 1.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KER28704.1 - 6.2e-25 87.7 0.0 1.5e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 KER28704.1 - 3.5e-11 43.3 0.1 6.7e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain FYVE PF01363.21 KER28705.1 - 1.9e-22 79.2 33.6 3.8e-14 52.6 7.3 4.4 4 0 0 4 4 4 3 FYVE zinc finger GBP PF02263.19 KER28705.1 - 8.7e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KER28705.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KER28705.1 - 0.2 11.7 0.1 0.55 10.3 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain Beta-lactamase PF00144.24 KER28707.1 - 2.1e-26 93.0 0.0 2.9e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase EPSP_synthase PF00275.20 KER28707.1 - 0.086 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PDZ_6 PF17820.1 KER28708.1 - 2.4e-06 27.3 0.1 5.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER28708.1 - 0.00041 20.7 0.0 0.0058 16.9 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KER28708.1 - 0.021 15.1 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain MOZART2 PF12926.7 KER28709.1 - 3e-07 29.9 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated HPPK PF01288.20 KER28709.1 - 0.048 14.2 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Ribosomal_L15e PF00827.17 KER28713.1 - 2.1e-91 304.8 8.5 2.4e-91 304.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Peptidase_M16 PF00675.20 KER28715.1 - 4.6e-53 179.2 0.0 2.9e-52 176.6 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KER28715.1 - 2.7e-31 109.0 0.0 7.7e-30 104.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain SIX1_SD PF16878.5 KER28718.1 - 8.4e-42 142.2 0.1 1.9e-41 141.1 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KER28718.1 - 3.5e-12 46.0 0.8 8.5e-12 44.7 0.3 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KER28718.1 - 1.4e-10 40.8 0.6 3.8e-10 39.5 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF3678 PF12435.8 KER28718.1 - 6.7 6.2 7.7 22 4.5 7.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Sporozoite_P67 PF05642.11 KER28719.1 - 0.00061 18.0 5.2 0.00078 17.7 5.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop14 PF04147.12 KER28719.1 - 0.025 12.8 22.1 0.027 12.7 22.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KER28719.1 - 0.036 12.2 34.0 0.043 11.9 34.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER28719.1 - 0.064 12.7 22.0 0.072 12.5 22.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER28719.1 - 0.28 10.5 16.6 0.29 10.4 16.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KER28719.1 - 0.33 9.2 18.3 0.38 9.0 18.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KER28719.1 - 0.57 8.6 16.4 0.71 8.3 16.4 1.0 1 0 0 1 1 1 0 Mpp10 protein zf-GRF PF06839.12 KER28719.1 - 0.95 9.6 3.5 0.83 9.8 1.3 2.0 2 1 0 2 2 1 0 GRF zinc finger RRN3 PF05327.11 KER28719.1 - 1.2 7.6 21.0 1.3 7.4 21.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2796 PF10986.8 KER28719.1 - 1.9 8.5 10.0 2.6 8.0 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF4637 PF15470.6 KER28719.1 - 2 8.1 10.7 2.9 7.6 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sigma70_ner PF04546.13 KER28719.1 - 2.2 8.1 19.4 3.6 7.4 19.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.11 KER28719.1 - 2.4 7.4 8.4 3.4 7.0 8.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 KER28719.1 - 2.6 7.1 41.9 4.1 6.5 41.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 KER28719.1 - 2.7 7.5 18.9 3 7.4 18.9 1.2 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 KER28719.1 - 2.8 7.7 8.8 3 7.6 8.8 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 KER28719.1 - 3.3 6.4 5.0 3.4 6.4 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 KER28719.1 - 4.7 6.8 7.5 5.9 6.5 7.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CobT PF06213.12 KER28719.1 - 5.9 6.2 19.4 7.8 5.8 19.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Drc1-Sld2 PF11719.8 KER28719.1 - 6.4 6.2 6.7 7.6 6.0 6.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SIX1_SD PF16878.5 KER28720.1 - 6.1e-40 136.2 0.0 1.2e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 KER28720.1 - 1.3e-15 57.0 0.2 3.8e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER28720.1 - 3.7e-11 42.7 0.7 7.4e-11 41.8 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.13 KER28720.1 - 0.0098 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain YdaS_antitoxin PF15943.5 KER28720.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KER28720.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.6 KER28720.1 - 0.064 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KER28720.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_26 PF13443.6 KER28720.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain tRNA-synt_1f PF01921.18 KER28720.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) JHD PF17811.1 KER28721.1 - 3.1e-17 63.0 0.1 7.2e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 Jumonji helical domain Pkinase PF00069.25 KER28723.1 - 1.4e-65 221.2 0.0 2.5e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.18 KER28723.1 - 1.5e-38 130.8 1.4 1.5e-18 66.8 0.1 2.8 3 0 0 3 3 3 2 POLO box duplicated region Pkinase_Tyr PF07714.17 KER28723.1 - 4.3e-37 127.8 0.0 6.8e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER28723.1 - 4.5e-06 26.2 0.0 1.5e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER28723.1 - 7.8e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cpn60_TCP1 PF00118.24 KER28725.1 - 3.4e-154 514.1 2.6 1.1e-122 410.2 0.3 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family gag-asp_proteas PF13975.6 KER28725.1 - 1.8e-06 28.4 0.0 4.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER28725.1 - 6.1e-06 26.8 0.0 2.1e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER28725.1 - 0.00059 20.1 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Transglut_i_TM PF14400.6 KER28725.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices UAA PF08449.11 KER28726.1 - 7.2e-42 143.6 7.9 8.2e-42 143.4 7.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KER28726.1 - 0.0036 17.5 19.0 0.005 17.0 17.3 2.0 1 1 2 3 3 3 1 EamA-like transporter family TPT PF03151.16 KER28726.1 - 0.0047 16.3 3.6 0.0065 15.9 3.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Rtf2 PF04641.12 KER28727.1 - 7.6e-70 235.3 3.2 2.9e-69 233.3 3.2 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KER28727.1 - 0.037 14.2 0.1 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Herpes_DNAp_acc PF04929.12 KER28727.1 - 1.5 7.7 6.7 2.2 7.2 6.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Chorein_N PF12624.7 KER28728.1 - 2.4e-18 66.3 0.1 5.8e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 KER28728.1 - 1.4e-07 31.4 0.0 0.007 16.2 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Arg_repressor_C PF02863.18 KER28728.1 - 0.17 11.8 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Gelsolin PF00626.22 KER28730.1 - 9.2e-49 163.3 1.5 7.9e-12 44.9 0.0 8.2 7 1 0 7 7 7 4 Gelsolin repeat LRR_8 PF13855.6 KER28730.1 - 1.7e-30 104.6 37.0 1e-10 41.2 4.8 6.7 2 1 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KER28730.1 - 5.4e-25 87.1 42.0 1.3e-05 25.4 3.5 8.0 3 2 3 8 8 8 7 Leucine Rich repeats (2 copies) RhoGEF PF00621.20 KER28730.1 - 7.1e-23 81.8 0.0 2.9e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain Snapin_Pallidin PF14712.6 KER28730.1 - 3.8e-08 33.6 10.1 5.5e-05 23.5 0.2 5.2 5 0 0 5 5 5 2 Snapin/Pallidin CRAL_TRIO PF00650.20 KER28730.1 - 0.00038 20.2 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 CRAL/TRIO domain LRR_9 PF14580.6 KER28730.1 - 0.0013 18.3 17.7 0.2 11.1 2.0 4.3 1 1 3 4 4 4 3 Leucine-rich repeat PH_10 PF15411.6 KER28730.1 - 0.0048 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER28730.1 - 0.056 13.9 0.0 0.26 11.8 0.0 2.2 2 0 0 2 2 1 0 PH domain CRAL_TRIO_2 PF13716.6 KER28730.1 - 0.066 13.4 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain LRR_5 PF13306.6 KER28730.1 - 0.069 13.1 0.1 1.3 9.0 0.0 2.7 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KER28730.1 - 6 7.8 39.3 6.7 7.7 0.2 11.0 13 0 0 13 13 10 0 Leucine Rich Repeat Ras PF00071.22 KER28733.1 - 7.1e-44 149.3 0.0 8.7e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER28733.1 - 9.3e-25 87.2 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER28733.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER28733.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER28733.1 - 0.046 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KER28733.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4200 PF13863.6 KER28734.1 - 1e-18 67.9 27.1 1e-18 67.9 27.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KER28734.1 - 0.53 10.3 27.7 0.13 12.3 15.8 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SopE_GEF PF07487.13 KER28734.1 - 0.63 10.1 7.1 7.4 6.7 0.0 2.9 3 0 0 3 3 3 0 SopE GEF domain DUF3782 PF12644.7 KER28734.1 - 3.3 7.9 5.6 0.81 9.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Tektin PF03148.14 KER28735.1 - 1.4e-131 438.8 33.5 2e-131 438.3 33.5 1.2 1 0 0 1 1 1 1 Tektin family DASH_Dad4 PF08650.10 KER28735.1 - 0.012 15.6 0.7 2.4 8.2 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 Laminin_II PF06009.12 KER28735.1 - 0.018 15.1 0.4 0.018 15.1 0.4 4.9 1 1 5 6 6 6 0 Laminin Domain II Ribosomal_L18_c PF14204.6 KER28735.1 - 0.031 15.2 1.4 0.13 13.2 0.5 2.5 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region MitMem_reg PF13012.6 KER28735.1 - 0.076 13.4 8.6 2 8.9 0.3 3.8 1 1 1 3 3 3 0 Maintenance of mitochondrial structure and function DHC PF09626.10 KER28735.1 - 0.2 12.5 3.2 7.7 7.4 0.1 2.6 2 0 0 2 2 2 0 Dihaem cytochrome c Flu_NS2 PF00601.19 KER28735.1 - 0.43 10.9 8.0 0.48 10.7 0.3 3.9 2 1 2 5 5 5 0 Influenza non-structural protein (NS2) DUF948 PF06103.11 KER28735.1 - 0.49 10.7 11.9 5.4 7.3 0.5 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 KER28735.1 - 1.1 9.1 8.9 0.14 12.0 2.1 2.6 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 KER28735.1 - 1.3 6.9 19.9 4.4 5.1 9.5 3.0 1 1 1 3 3 3 0 Prominin DUF4164 PF13747.6 KER28735.1 - 2.6 8.4 27.2 0.12 12.6 5.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 KER28735.1 - 5.8 7.0 12.6 11 6.0 2.2 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus YebO PF13974.6 KER28735.1 - 7.3 6.7 8.5 25 5.1 0.9 2.7 2 0 0 2 2 2 0 YebO-like protein Pkinase PF00069.25 KER28736.1 - 1.3e-41 142.7 0.0 1.7e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER28736.1 - 4.2e-30 104.9 0.0 5.7e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER28736.1 - 1.8e-05 24.2 0.0 4.8e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KER28736.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER28736.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Tubulin PF00091.25 KER28737.1 - 4e-68 229.5 0.0 5.5e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER28737.1 - 4e-52 175.7 0.0 6.3e-52 175.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER28737.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KER28738.1 - 5.2e-63 212.8 0.0 7e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER28738.1 - 9.7e-51 171.2 0.1 1.5e-50 170.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER28738.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain GTP_EFTU PF00009.27 KER28739.1 - 1.8e-52 177.7 0.3 2.5e-52 177.2 0.3 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KER28739.1 - 1.9e-15 57.1 0.0 4.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KER28739.1 - 3.8e-15 56.0 0.8 7.3e-15 55.1 0.8 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KER28739.1 - 0.00083 19.4 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GpcrRhopsn4 PF10192.9 KER28740.1 - 0.0011 18.4 0.1 0.33 10.3 0.0 2.7 2 0 0 2 2 2 2 Rhodopsin-like GPCR transmembrane domain zf-C2H2 PF00096.26 KER28741.1 - 2.1e-21 75.1 22.4 3.4e-05 24.1 0.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER28741.1 - 2.2e-16 59.2 22.6 0.00055 20.6 0.3 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER28741.1 - 2.5e-16 59.2 20.9 2.1e-05 24.7 0.1 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER28741.1 - 2.8e-08 33.8 10.5 0.1 12.9 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER28741.1 - 2.3e-07 30.7 18.9 0.018 15.0 0.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KER28741.1 - 2.4e-07 30.9 14.6 0.00024 21.4 0.2 4.8 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KER28741.1 - 0.00046 20.4 10.4 0.075 13.3 4.5 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 KER28741.1 - 0.0025 18.1 11.2 0.066 13.5 3.3 3.3 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-MYST PF17772.1 KER28741.1 - 0.015 14.9 4.9 1.4 8.6 0.0 3.1 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 KER28741.1 - 0.039 14.6 11.9 0.097 13.4 5.1 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KER28741.1 - 0.11 12.2 0.4 0.11 12.2 0.4 4.4 5 1 0 5 5 2 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 KER28741.1 - 0.14 12.3 8.6 1.6 8.9 2.2 4.0 4 1 0 4 4 4 0 Zinc ribbon domain CpXC PF14353.6 KER28741.1 - 0.4 10.7 14.8 2.1 8.4 0.3 4.9 2 2 2 4 4 4 0 CpXC protein zf_UBZ PF18439.1 KER28741.1 - 0.42 10.2 8.9 7.1 6.3 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-nanos PF05741.13 KER28741.1 - 0.75 10.1 9.1 0.077 13.2 1.7 3.1 3 1 0 3 3 3 0 Nanos RNA binding domain zf-FCS PF06467.14 KER28741.1 - 0.76 9.8 6.8 1.5 8.8 0.2 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-BED PF02892.15 KER28741.1 - 2.8 8.1 20.0 1.9 8.6 3.7 4.5 1 1 2 3 3 3 0 BED zinc finger Desulfoferrod_N PF06397.12 KER28741.1 - 3.2 7.5 7.7 3.2 7.4 0.4 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain C1_4 PF07975.12 KER28741.1 - 3.5 7.9 14.9 1.6 9.0 2.8 3.7 3 2 1 4 4 4 0 TFIIH C1-like domain zf-HIT PF04438.16 KER28741.1 - 3.5 7.6 10.5 33 4.5 0.0 3.6 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_2 PF12756.7 KER28741.1 - 3.5 8.0 18.2 1 9.7 0.5 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KER28741.1 - 3.7 7.4 19.9 3.3 7.5 0.2 4.6 5 0 0 5 5 4 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 KER28741.1 - 9.4 6.0 12.2 22 4.8 0.1 3.9 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KER28745.1 - 1.1e-10 41.4 28.7 0.021 15.2 0.1 5.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER28745.1 - 9.2e-10 38.5 28.9 0.049 14.5 2.0 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER28745.1 - 3.2e-09 36.8 28.1 4e-06 27.0 1.3 6.0 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER28745.1 - 0.0075 16.2 32.0 0.23 11.5 3.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 KER28745.1 - 0.013 15.9 28.4 0.29 11.6 1.4 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KER28745.1 - 0.031 14.6 9.8 0.12 12.7 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-MYST PF17772.1 KER28745.1 - 0.071 12.7 10.5 0.86 9.3 2.0 3.6 2 1 1 3 3 3 0 MYST family zinc finger domain Baculo_IE-1 PF05290.11 KER28745.1 - 0.075 13.0 4.5 2.6 8.0 0.1 3.0 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_3rep PF18868.1 KER28745.1 - 0.11 13.2 18.1 5.1 7.8 0.1 5.2 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KER28745.1 - 0.11 12.6 13.7 13 6.0 0.2 5.4 5 0 0 5 5 5 0 Zinc ribbon domain BolA PF01722.18 KER28745.1 - 0.2 11.9 1.8 15 5.9 0.7 2.8 2 0 0 2 2 2 0 BolA-like protein zf-FCS PF06467.14 KER28745.1 - 0.21 11.5 16.8 3.1 7.8 0.0 5.5 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf_UBZ PF18439.1 KER28745.1 - 0.34 10.6 14.3 6.8 6.4 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger ARS2 PF04959.13 KER28745.1 - 0.39 11.1 4.3 20 5.5 0.0 3.3 2 1 1 3 3 3 0 Arsenite-resistance protein 2 zf-C2H2_11 PF16622.5 KER28745.1 - 1.4 8.7 14.7 11 5.9 0.2 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KER28745.1 - 1.8 8.6 18.8 4.3 7.4 0.2 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KER28745.1 - 2.5 8.4 10.1 2.9 8.2 0.4 3.3 3 0 0 3 3 3 0 zinc-finger-containing domain zf-ribbon_3 PF13248.6 KER28745.1 - 9.4 5.8 10.5 3.7 7.1 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Bromodomain PF00439.25 KER28747.1 - 3.3e-16 59.1 0.0 6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 KER28747.1 - 1.3e-13 51.0 0.0 7.7e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3512) Pullulanase_Ins PF18494.1 KER28747.1 - 0.023 15.1 0.1 4.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Pullulanase Ins domain DUF4594 PF15266.6 KER28747.1 - 0.041 14.2 1.0 18 5.6 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4594) Cnd2 PF05786.14 KER28749.1 - 0.066 11.9 1.0 0.067 11.8 1.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Ig_3 PF13927.6 KER28753.1 - 2.6e-15 56.8 0.0 1.9e-08 34.8 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 KER28753.1 - 5.8e-12 45.8 0.0 3e-06 27.5 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KER28753.1 - 5.3e-10 39.5 0.0 0.0038 17.4 0.0 3.7 3 1 1 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.16 KER28753.1 - 7.1e-10 38.8 0.0 2.2e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KER28753.1 - 4e-09 36.5 0.0 4.8e-05 23.4 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain Ig_6 PF18452.1 KER28753.1 - 3.6e-05 23.2 0.0 0.042 13.4 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Izumo-Ig PF16706.5 KER28753.1 - 0.00047 20.2 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain C2-set PF05790.15 KER28753.1 - 0.18 12.0 0.0 3 8.1 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain V-set PF07686.17 KER28754.1 - 0.00069 19.8 0.3 0.71 10.1 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KER28754.1 - 0.004 17.7 0.3 2.1 9.0 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Stevor PF17410.2 KER28754.1 - 0.053 13.1 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KER28754.1 - 0.059 13.3 0.5 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF2369 PF10179.9 KER28754.1 - 0.9 10.0 2.7 5 7.6 2.7 2.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Kelch_1 PF01344.25 KER28755.1 - 8.1e-64 211.0 14.1 6.5e-14 51.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KER28755.1 - 1.3e-41 139.5 12.1 7.4e-07 29.2 0.1 7.2 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KER28755.1 - 5.7e-31 106.2 14.6 2.2e-05 24.6 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.31 KER28755.1 - 8.1e-28 96.9 0.6 8.9e-27 93.5 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 KER28755.1 - 2.9e-25 88.0 17.3 6.8e-05 22.8 0.1 6.7 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KER28755.1 - 3.4e-21 74.3 9.5 0.00041 20.2 0.2 6.5 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 KER28755.1 - 2.3e-13 50.1 1.0 5.3e-13 49.0 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KER28755.1 - 1.9e-09 37.3 5.4 0.017 15.1 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Spindle_Spc25 PF08234.12 KER28756.1 - 1.4e-09 38.0 0.0 3.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KER28756.1 - 0.0071 15.3 1.8 0.0097 14.8 1.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 KER28756.1 - 0.012 15.8 3.7 0.016 15.4 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_tail_T PF06223.12 KER28756.1 - 0.027 15.0 0.8 0.086 13.4 0.3 1.9 2 0 0 2 2 2 0 Minor tail protein T Bacillus_HBL PF05791.11 KER28756.1 - 0.039 13.8 0.3 0.081 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FUSC PF04632.12 KER28756.1 - 0.1 11.1 0.8 0.14 10.7 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 KER28756.1 - 0.11 12.8 4.4 0.21 11.8 4.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 KER28756.1 - 0.18 12.2 2.0 0.63 10.4 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.9 KER28756.1 - 0.32 11.2 3.5 0.47 10.7 3.0 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein PI3K_P85_iSH2 PF16454.5 KER28756.1 - 0.53 9.9 5.4 0.78 9.3 4.9 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain UQ_con PF00179.26 KER28757.1 - 8.1e-37 126.0 0.0 1.4e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RhoGAP PF00620.27 KER28759.1 - 9.5e-45 152.1 0.4 3.2e-39 134.2 0.1 2.4 2 0 0 2 2 2 2 RhoGAP domain WW PF00397.26 KER28759.1 - 5.6e-06 26.3 7.6 0.017 15.2 0.8 2.9 2 1 0 2 2 2 2 WW domain PH_9 PF15410.6 KER28759.1 - 0.072 13.5 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KER28759.1 - 0.1 13.1 0.1 0.55 10.8 0.0 2.2 2 0 0 2 2 2 0 PH domain Acetyltransf_11 PF13720.6 KER28759.1 - 0.18 12.3 0.0 0.59 10.6 0.0 1.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 NAD_binding_4 PF07993.12 KER28765.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein DUF4074 PF13293.6 KER28767.1 - 0.03 14.6 0.2 0.076 13.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) SMN PF06003.12 KER28769.1 - 7.7e-14 51.6 4.9 1.9e-13 50.3 2.0 2.6 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KER28769.1 - 0.00053 20.0 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 Tudor domain DUF4537 PF15057.6 KER28769.1 - 0.018 15.1 0.0 0.06 13.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Kinesin PF00225.23 KER28770.1 - 2.1e-93 312.9 5.9 2.7e-50 171.2 1.4 2.8 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KER28770.1 - 4.8e-18 65.5 2.3 8.6e-15 55.0 2.3 3.2 1 1 0 1 1 1 1 Microtubule binding Baculo_PEP_C PF04513.12 KER28770.1 - 0.0021 18.1 2.1 0.0021 18.1 2.1 5.8 5 2 1 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus ERM PF00769.19 KER28770.1 - 0.0059 16.5 16.1 0.0059 16.5 16.1 4.4 4 1 1 5 5 5 1 Ezrin/radixin/moesin family SHE3 PF17078.5 KER28770.1 - 0.0073 16.1 13.7 0.0073 16.1 13.7 4.3 4 0 0 4 4 4 2 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 KER28770.1 - 0.012 16.1 16.0 0.012 16.1 16.0 5.7 3 2 2 5 5 5 0 Apg6 coiled-coil region CT_C_D PF02682.16 KER28770.1 - 0.31 10.7 4.5 0.16 11.7 1.7 2.0 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D IFT57 PF10498.9 KER28770.1 - 0.51 9.3 39.1 0.48 9.4 14.9 3.8 3 1 0 3 3 3 0 Intra-flagellar transport protein 57 Filament PF00038.21 KER28770.1 - 0.51 9.9 51.2 0.24 10.9 8.8 4.7 3 2 1 4 4 4 0 Intermediate filament protein DUF641 PF04859.12 KER28770.1 - 0.53 10.6 33.5 1.1 9.6 8.8 5.1 4 1 0 4 4 4 0 Plant protein of unknown function (DUF641) DUF244 PF03112.14 KER28770.1 - 0.61 9.9 7.4 4.4 7.1 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein family (ORF7) DUF Spc7 PF08317.11 KER28770.1 - 0.9 8.4 55.0 0.041 12.8 17.9 3.9 3 1 1 4 4 4 0 Spc7 kinetochore protein PLAC9 PF15205.6 KER28770.1 - 1.4 9.4 3.5 1.1 9.7 0.2 2.6 2 0 0 2 2 2 0 Placenta-specific protein 9 TMP_2 PF06791.13 KER28770.1 - 3.1 7.4 6.1 1.6 8.4 0.3 2.7 2 1 0 2 2 2 0 Prophage tail length tape measure protein Cnn_1N PF07989.11 KER28770.1 - 5.1 7.3 43.6 0.39 10.9 0.3 7.3 5 2 2 7 7 7 0 Centrosomin N-terminal motif 1 DUF4055 PF13264.6 KER28770.1 - 8.6 6.5 7.6 8.2 6.6 2.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Golgin_A5 PF09787.9 KER28770.1 - 9.7 5.6 57.5 0.058 12.8 7.0 4.6 1 1 2 4 4 4 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 KER28770.1 - 9.9 5.9 28.4 2.3 8.0 5.0 5.0 4 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) VPS11_C PF12451.8 KER28771.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal SPATA48 PF15073.6 KER28772.1 - 3.8e-11 43.4 0.5 7.3e-11 42.5 0.5 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Aminotran_1_2 PF00155.21 KER28772.1 - 0.0021 17.3 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Inhibitor_I10 PF12559.8 KER28773.1 - 0.038 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine endopeptidase inhibitors NIF PF03031.18 KER28774.1 - 2.8e-51 173.4 0.1 4.5e-51 172.7 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase E3_UbLigase_RBR PF18091.1 KER28775.1 - 0.021 14.9 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain DUF1126 PF06565.12 KER28776.1 - 4.4e-100 328.6 1.4 5.3e-36 122.6 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 KER28776.1 - 0.0013 19.1 1.7 0.0037 17.7 1.7 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KER28776.1 - 0.007 15.8 3.0 0.049 13.2 0.8 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER28776.1 - 0.015 15.2 0.9 0.27 11.3 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain eIF-5_eIF-2B PF01873.17 KER28776.1 - 0.042 13.7 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Tmemb_cc2 PF10267.9 KER28777.1 - 4e-10 39.4 28.1 1.4e-07 31.0 3.2 3.2 2 2 1 3 3 3 2 Predicted transmembrane and coiled-coil 2 protein HxlR PF01638.17 KER28777.1 - 0.0064 16.3 0.4 2.5 8.0 0.0 2.9 2 0 0 2 2 2 2 HxlR-like helix-turn-helix IFP_35_N PF07334.13 KER28777.1 - 0.068 13.3 3.4 0.1 12.7 0.7 2.7 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DHR10 PF18595.1 KER28777.1 - 0.075 13.1 32.6 0.13 12.3 7.4 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain ArnB_C PF18677.1 KER28777.1 - 0.89 9.7 9.6 7 6.8 1.1 3.0 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain DUF4665 PF15679.5 KER28777.1 - 2.2 9.0 3.7 37 5.0 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Apolipoprotein PF01442.18 KER28777.1 - 2.2 8.1 25.9 0.21 11.4 19.2 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF5105 PF17118.5 KER28777.1 - 3.5 7.4 7.5 19 5.0 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5105) Acetyltransf_3 PF13302.7 KER28779.1 - 4.4e-18 66.3 0.0 7.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KER28779.1 - 0.00023 21.4 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KER28779.1 - 0.0029 17.5 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KER28779.1 - 0.035 13.8 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_transf_18 PF15024.6 KER28780.1 - 1.9e-147 492.3 0.0 1.3e-127 426.8 0.0 4.3 4 1 0 5 5 5 3 Glycosyltransferase family 18 DUF4525 PF15027.6 KER28780.1 - 1.8e-14 53.6 0.0 3.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF1604 PF07713.13 KER28781.1 - 0.21 11.4 0.3 25 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Glyco_transf_18 PF15024.6 KER28783.1 - 1.6e-67 228.4 0.9 3e-28 98.7 0.0 4.0 1 1 2 3 3 3 3 Glycosyltransferase family 18 Suf PF05843.14 KER28783.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SNF2_N PF00176.23 KER28784.1 - 2e-53 181.3 0.0 1.2e-37 129.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KER28784.1 - 4.4e-14 52.8 0.0 9.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KER28784.1 - 1.8e-07 30.6 0.0 7.8e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KER28784.1 - 0.011 15.8 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit His_Phos_2 PF00328.22 KER28785.1 - 1.5e-23 83.8 0.1 2.4e-21 76.5 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SVIP PF15811.5 KER28786.1 - 0.48 10.9 4.6 2 8.9 4.6 2.0 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Pkinase_Tyr PF07714.17 KER28788.1 - 3.1e-12 46.3 0.0 1.1e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KER28788.1 - 8.8e-09 35.1 0.0 1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain LEDGF PF11467.8 KER28790.1 - 3.6e-18 65.3 2.4 6.5e-18 64.5 2.4 1.4 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Peptidase_C13 PF01650.18 KER28791.1 - 3.6e-68 229.9 0.1 4.8e-68 229.5 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C25 PF01364.18 KER28791.1 - 0.0038 16.5 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 Peptidase_C14 PF00656.22 KER28791.1 - 0.0091 16.0 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain NOA36 PF06524.12 KER28796.1 - 0.031 13.6 15.7 0.034 13.5 15.7 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KER28796.1 - 0.11 12.0 4.9 0.1 12.2 4.9 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KER28796.1 - 0.3 9.2 7.9 0.28 9.3 7.9 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KER28796.1 - 0.95 9.2 16.5 1.3 8.7 16.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KER28796.1 - 1.1 7.5 7.6 1.1 7.4 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 KER28796.1 - 1.1 8.3 22.3 1.2 8.2 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 KER28796.1 - 1.3 9.3 16.2 1.3 9.2 16.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 KER28796.1 - 3.4 7.0 9.8 3.8 6.8 9.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KER28796.1 - 4 5.4 23.0 4.7 5.2 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KER28796.1 - 4.2 5.8 8.9 4.1 5.8 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_C13 PF01650.18 KER28797.1 - 1.8e-06 27.7 0.1 2.4e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pet100 PF09803.9 KER28798.1 - 0.00022 21.7 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 Pet100 E1_DerP2_DerF2 PF02221.15 KER28798.1 - 0.00038 20.9 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 ML domain RRM_5 PF13893.6 KER28800.1 - 8.6e-42 141.7 0.0 1.3e-35 121.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER28800.1 - 4.1e-19 68.2 0.0 2.1e-07 30.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KER28800.1 - 1.4e-14 54.1 0.1 2.4e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 KER28800.1 - 6.4e-05 22.7 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KER28800.1 - 0.00032 20.7 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RL PF17797.1 KER28800.1 - 0.00045 20.1 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 RL domain GP17 PF17420.2 KER28800.1 - 0.024 14.8 0.1 0.58 10.4 0.1 2.3 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 RRM_3 PF08777.11 KER28800.1 - 0.22 11.6 0.0 0.89 9.6 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif RVT_1 PF00078.27 KER28801.1 - 4.3e-06 26.4 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 KER28802.1 - 1.2e-88 296.7 0.0 1.6e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER28802.1 - 3.7e-46 157.6 0.0 5.1e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER28802.1 - 2.8e-16 59.4 0.2 5.9e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 KER28802.1 - 1e-13 50.7 0.0 2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER28802.1 - 4.2e-09 36.1 0.0 9.3e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER28802.1 - 2.7e-05 23.8 0.0 6.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KER28802.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KER28802.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER28802.1 - 0.031 13.2 0.0 0.06 12.3 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain ubiquitin PF00240.23 KER28803.1 - 2.8e-10 39.8 0.4 3.3e-10 39.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KER28804.1 - 2.4e-28 97.6 3.7 3.6e-14 52.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KER28804.1 - 9.4e-20 70.1 10.0 1.5e-19 69.4 10.0 1.4 1 0 0 1 1 1 1 XPC-binding domain DUF1296 PF06972.11 KER28804.1 - 0.013 15.7 0.0 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) UBA_3 PF09288.10 KER28804.1 - 0.024 14.4 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2999 PF11212.8 KER28804.1 - 0.059 13.6 0.3 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) DUF3135 PF11333.8 KER28804.1 - 0.084 13.1 1.6 0.14 12.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) ubiquitin PF00240.23 KER28804.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DUF3306 PF11748.8 KER28804.1 - 5.1 8.0 6.1 0.7 10.8 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3306) CCDC106 PF15794.5 KER28806.1 - 0.00096 18.9 8.5 0.01 15.5 0.5 2.5 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 106 DUF1635 PF07795.11 KER28806.1 - 0.0058 16.5 8.1 0.0074 16.2 0.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1635) YabA PF06156.13 KER28806.1 - 0.028 15.1 5.3 0.95 10.1 0.1 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DUF4164 PF13747.6 KER28806.1 - 0.032 14.5 1.3 0.032 14.5 1.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) GOLGA2L5 PF15070.6 KER28806.1 - 0.1 11.3 4.5 1.3 7.6 0.0 2.6 3 0 0 3 3 3 0 Putative golgin subfamily A member 2-like protein 5 HAUS6_N PF14661.6 KER28806.1 - 0.22 11.1 4.5 0.8 9.2 0.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF948 PF06103.11 KER28806.1 - 0.27 11.5 0.2 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 KER28806.1 - 0.62 9.3 10.6 0.61 9.4 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 KER28806.1 - 1 8.7 12.4 0.19 11.0 0.5 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.17 KER28806.1 - 1.4 8.9 4.0 3.8 7.5 0.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KER28806.1 - 4.7 7.9 11.5 38 5.0 0.2 3.6 3 0 0 3 3 3 0 SlyX betaPIX_CC PF16523.5 KER28806.1 - 7 6.6 9.9 5.1 7.0 0.3 3.4 4 0 0 4 4 4 0 betaPIX coiled coil RINT1_TIP1 PF04437.13 KER28807.1 - 1.7e-64 218.6 0.0 7.1e-63 213.2 0.0 2.7 2 1 0 2 2 2 1 RINT-1 / TIP-1 family RRM_1 PF00076.22 KER28808.1 - 1.9e-16 59.6 0.0 3.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER28808.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 KER28808.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER28809.1 - 5.1e-40 135.1 0.1 4.7e-20 71.2 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER28809.1 - 0.0058 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KER28809.1 - 0.019 15.2 0.0 2.9 8.2 0.0 2.5 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_occluded PF16842.5 KER28809.1 - 0.03 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_2 PF04059.12 KER28809.1 - 0.13 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 Autophagy_N PF03986.13 KER28810.1 - 1.5e-43 148.0 0.1 2.4e-43 147.4 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain ARF7EP_C PF14949.6 KER28810.1 - 9.8e-29 100.1 3.6 2.1e-28 99.0 3.6 1.5 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Autophagy_act_C PF03987.15 KER28810.1 - 8.1e-13 48.7 0.2 2.5e-12 47.2 0.2 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain AAA_6 PF12774.7 KER28811.1 - 4e-162 538.8 0.1 1.4e-159 530.4 0.0 3.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER28811.1 - 4.1e-145 483.9 5.9 4.1e-145 483.9 5.9 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KER28811.1 - 1.6e-102 342.9 0.1 4.5e-102 341.4 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KER28811.1 - 8.3e-102 340.0 0.3 2e-101 338.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER28811.1 - 4.6e-89 297.3 5.1 1.4e-88 295.7 0.0 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER28811.1 - 1.5e-80 269.0 0.1 1.5e-76 255.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KER28811.1 - 8.6e-55 185.0 0.0 2.4e-54 183.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KER28811.1 - 2.3e-46 158.4 4.3 3.9e-46 157.7 4.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER28811.1 - 1.7e-44 150.7 0.0 1.1e-43 148.2 0.0 2.5 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 KER28811.1 - 8.8e-31 106.7 0.4 6.1e-30 103.9 0.4 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KER28811.1 - 2.7e-21 75.7 0.0 2e-20 72.9 0.0 2.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KER28811.1 - 7.1e-21 74.7 0.1 3.6e-06 27.0 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KER28811.1 - 2.7e-07 30.9 1.7 0.14 12.4 0.0 5.0 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KER28811.1 - 7.5e-06 26.4 0.3 10 6.5 0.0 5.8 6 0 0 6 6 4 0 AAA ATPase domain AAA PF00004.29 KER28811.1 - 4.9e-05 23.8 3.9 1.6 9.1 0.0 5.2 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KER28811.1 - 0.00023 20.3 0.0 0.3 10.1 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein ResIII PF04851.15 KER28811.1 - 0.00059 19.9 2.4 0.78 9.7 0.0 3.2 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KER28811.1 - 0.00059 20.4 0.1 0.29 11.7 0.0 4.4 5 0 0 5 5 3 1 AAA domain Mg_chelatase PF01078.21 KER28811.1 - 0.0015 17.9 0.0 0.68 9.3 0.0 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KER28811.1 - 0.0043 16.9 0.0 9.7 5.9 0.0 3.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KER28811.1 - 0.015 15.6 2.1 2.5 8.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KER28811.1 - 0.02 14.6 0.2 23 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KER28811.1 - 0.025 15.0 0.0 83 3.6 0.0 3.8 3 0 0 3 3 3 0 RNA helicase DUF853 PF05872.12 KER28811.1 - 0.074 11.6 0.6 8.3 4.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 KER28811.1 - 0.12 12.5 0.1 44 4.2 0.0 3.7 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KER28811.1 - 0.53 9.7 2.7 3.6 7.0 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein AAA_24 PF13479.6 KER28811.1 - 1.9 8.2 3.6 91 2.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain DUF4508 PF14969.6 KER28813.1 - 2.7e-15 56.4 1.4 9.2e-15 54.7 1.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4508) Band_7 PF01145.25 KER28814.1 - 2e-07 31.2 0.0 6.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family SCP2 PF02036.17 KER28814.1 - 0.00091 19.7 0.1 0.0031 18.0 0.1 1.9 1 0 0 1 1 1 1 SCP-2 sterol transfer family FAR1 PF03101.15 KER28814.1 - 0.0028 18.3 0.5 0.0072 17.0 0.5 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain TMF_DNA_bd PF12329.8 KER28816.1 - 8e-08 32.2 14.5 8e-08 32.2 14.5 7.6 2 2 5 7 7 7 1 TATA element modulatory factor 1 DNA binding Apc13p PF05839.11 KER28816.1 - 0.088 13.0 5.3 0.032 14.4 1.1 2.6 2 0 0 2 2 2 0 Apc13p protein HALZ PF02183.18 KER28816.1 - 8.5 6.7 32.8 0.072 13.3 1.1 5.6 5 1 1 6 6 6 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 KER28816.1 - 8.9 6.5 82.4 0.073 13.2 12.4 5.9 1 1 4 5 5 5 0 Tropomyosin like Pyr_redox_2 PF07992.14 KER28817.1 - 9.8e-29 100.5 0.0 4e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 KER28817.1 - 4e-12 46.6 2.5 2e-08 34.7 0.1 3.7 3 1 0 3 3 3 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_3 PF13738.6 KER28817.1 - 0.0061 15.9 0.8 1.5 8.0 1.1 3.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KER28817.1 - 0.016 14.8 1.8 1.7 8.1 1.7 3.4 3 1 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KER28817.1 - 0.024 14.9 0.5 0.024 14.9 0.5 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KER28817.1 - 0.026 13.6 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KER28817.1 - 0.03 14.9 0.2 4.8 7.8 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KER28817.1 - 0.045 13.7 2.8 16 5.5 0.5 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KER28817.1 - 0.092 11.8 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KER28817.1 - 0.12 11.1 0.8 0.3 9.8 0.6 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KER28817.1 - 0.19 10.9 0.8 0.28 10.4 0.2 1.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KER28817.1 - 0.46 9.5 5.0 0.1 11.7 1.5 1.6 2 0 0 2 2 2 0 FAD binding domain AA_permease PF00324.21 KER28819.1 - 1.9e-60 204.8 32.8 6.1e-41 140.5 6.2 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 KER28819.1 - 5.9e-46 157.4 0.7 3.4e-15 56.0 0.0 3.2 2 1 1 3 3 3 3 Solute carrier family 12 eIF-6 PF01912.18 KER28823.1 - 2.8e-32 111.7 0.6 1.4e-31 109.4 0.1 1.9 1 1 1 2 2 2 1 eIF-6 family FPL PF09758.9 KER28824.1 - 6.6e-44 149.5 6.4 1.3e-43 148.6 6.4 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein Invas_SpaK PF03519.14 KER28825.1 - 0.16 12.0 0.1 0.51 10.4 0.1 1.9 2 1 0 2 2 2 0 Invasion protein B family RT_RNaseH_2 PF17919.1 KER28826.1 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER28826.1 - 2.1e-05 24.8 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sec5 PF15469.6 KER28827.1 - 2e-40 138.7 0.0 3.6e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 TIG PF01833.24 KER28827.1 - 1.5e-08 34.6 1.0 4.1e-08 33.2 1.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Thioredoxin_9 PF14595.6 KER28827.1 - 0.11 12.3 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Sterol-sensing PF12349.8 KER28830.1 - 2.1e-19 69.9 5.5 1.7e-10 40.9 0.6 2.7 1 1 1 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KER28830.1 - 3.1e-15 55.4 0.0 6.5e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Patched family Pou PF00157.17 KER28832.1 - 1.8e-36 123.9 0.1 3.6e-36 122.9 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KER28832.1 - 5.1e-17 61.5 0.5 5.1e-17 61.5 0.5 2.0 2 0 0 2 2 2 1 Homeodomain RhlB PF12300.8 KER28832.1 - 0.0037 17.4 0.4 0.016 15.4 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent RNA helicase RhlB HTH_31 PF13560.6 KER28832.1 - 0.22 11.9 0.0 1.1 9.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Otopetrin PF03189.13 KER28833.1 - 2.5e-45 155.1 16.0 7e-18 64.7 1.4 3.4 1 1 2 3 3 3 3 Otopetrin DUF2197 PF09963.9 KER28833.1 - 0.16 12.3 1.6 27 5.1 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Jagunal PF07086.12 KER28834.1 - 1e-59 201.8 1.1 1.2e-59 201.6 1.1 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis PHD PF00628.29 KER28836.1 - 0.00046 20.0 5.5 0.001 18.9 5.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 KER28836.1 - 0.032 14.1 3.2 0.052 13.4 3.2 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein C1_2 PF03107.16 KER28836.1 - 8.5 6.8 8.7 11 6.4 5.5 2.4 2 0 0 2 2 2 0 C1 domain DUF2946 PF11162.8 KER28837.1 - 0.033 14.9 1.2 0.088 13.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) YTH PF04146.15 KER28838.1 - 2.3e-39 135.0 4.0 3.9e-39 134.3 0.5 2.7 2 1 0 2 2 2 1 YT521-B-like domain Ebola_NP PF05505.12 KER28838.1 - 0.99 7.6 9.4 1.8 6.8 9.4 1.4 1 1 0 1 1 1 0 Ebola nucleoprotein ABC_membrane PF00664.23 KER28839.1 - 7.1e-72 242.3 30.0 2.9e-37 128.8 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KER28839.1 - 6.8e-52 175.6 0.0 2.8e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KER28839.1 - 1e-10 41.5 6.6 0.005 16.3 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KER28839.1 - 2.5e-06 27.5 0.6 0.071 13.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KER28839.1 - 7.6e-06 25.6 0.6 0.035 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER28839.1 - 1.1e-05 25.4 0.1 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KER28839.1 - 2.7e-05 24.7 1.5 0.0089 16.5 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KER28839.1 - 0.00014 21.8 5.1 0.019 14.8 0.1 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KER28839.1 - 0.0016 18.6 2.8 0.047 13.8 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KER28839.1 - 0.002 18.5 0.0 2.8 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF815 PF05673.13 KER28839.1 - 0.0025 17.0 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 KER28839.1 - 0.0076 16.0 0.1 1.4 8.5 0.6 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KER28839.1 - 0.0097 15.2 0.2 0.71 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 KER28839.1 - 0.01 15.9 1.4 0.28 11.2 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KER28839.1 - 0.019 14.7 0.4 12 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KER28839.1 - 0.026 14.8 1.1 8.1 6.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KER28839.1 - 0.094 12.3 0.2 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAHP_snth_FXD PF18152.1 KER28839.1 - 0.25 11.2 0.5 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Laminin_N PF00055.17 KER28840.1 - 5.4e-39 134.2 0.2 5.4e-39 134.2 0.2 3.8 3 2 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 KER28840.1 - 5.3e-23 80.9 63.0 4.8e-09 36.2 13.4 4.2 4 0 0 4 4 4 3 Laminin EGF domain F5_F8_type_C PF00754.25 KER28840.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain BNR_6 PF15899.5 KER28840.1 - 0.43 10.8 1.6 1.3 9.3 1.6 1.8 1 0 0 1 1 1 0 BNR-Asp box repeat 7tm_1 PF00001.21 KER28841.1 - 4.2e-28 98.4 7.0 8.2e-28 97.4 7.0 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 KER28841.1 - 0.0012 18.5 9.7 0.0023 17.6 3.6 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KER28842.1 - 1.5e-09 37.6 2.6 1.8e-09 37.3 2.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AP_endonuc_2 PF01261.24 KER28842.1 - 0.19 11.1 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SH3BGR PF04908.15 KER28843.1 - 3.4e-23 81.7 0.1 3.4e-23 81.7 0.1 2.6 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein MSV199 PF10553.9 KER28843.1 - 0.013 15.7 0.2 0.013 15.7 0.2 1.9 2 0 0 2 2 2 0 MSV199 domain FancD2 PF14631.6 KER28844.1 - 2.4e-49 167.8 1.7 1.2e-33 115.8 0.5 4.8 4 1 0 4 4 4 4 Fanconi anaemia protein FancD2 nuclease Ras PF00071.22 KER28846.1 - 8.4e-24 84.0 0.0 6.7e-22 77.8 0.0 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER28846.1 - 2.4e-14 53.6 0.0 1.1e-12 48.2 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KER28846.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KER28846.1 - 0.0012 18.4 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KER28846.1 - 0.0061 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KER28846.1 - 0.015 14.7 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KER28846.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein M16C_assoc PF08367.11 KER28847.1 - 1e-57 195.1 0.0 2.1e-57 194.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KER28847.1 - 1.2e-13 51.5 0.0 8.6e-13 48.7 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain DUF1957 PF09210.11 KER28847.1 - 0.029 14.8 0.2 0.1 13.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Lig_chan PF00060.26 KER28850.1 - 2.7e-42 144.1 1.3 4.5e-42 143.4 1.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER28850.1 - 9.8e-37 125.7 0.1 1.7e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 KER28850.1 - 6.9e-30 104.3 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 KER28850.1 - 8.3e-14 51.6 0.0 2.2e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 KER28850.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Lig_chan PF00060.26 KER28851.1 - 3.1e-55 186.1 1.7 1.4e-50 171.0 1.0 2.5 2 0 0 2 2 2 2 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER28851.1 - 1.2e-35 122.2 0.0 2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 KER28851.1 - 5.8e-30 104.6 0.0 9.5e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 KER28851.1 - 1.5e-25 89.9 0.0 2.1e-20 73.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Cortexin PF11057.8 KER28851.1 - 3.4e-06 26.8 0.0 0.054 13.3 0.0 2.4 2 0 0 2 2 2 2 Cortexin of kidney DUF1850 PF08905.11 KER28851.1 - 0.0047 17.2 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1850) DUF5442 PF17514.2 KER28851.1 - 0.013 15.7 0.1 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Helicase_C PF00271.31 KER28852.1 - 1.4e-25 89.8 0.0 4.3e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER28852.1 - 1.1e-20 74.2 0.0 2e-19 70.0 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase PCMT PF01135.19 KER28853.1 - 1.4e-19 70.7 0.0 4.9e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) G-alpha PF00503.20 KER28857.1 - 1e-116 390.0 1.6 1.2e-116 389.7 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER28857.1 - 8.9e-14 51.3 1.3 6.2e-10 38.8 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER28857.1 - 0.0025 17.2 2.1 0.13 11.6 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KER28857.1 - 0.035 14.3 0.2 2.9 8.2 0.0 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KER28857.1 - 0.043 13.2 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Rota_NSP4 PF01452.16 KER28857.1 - 0.1 12.3 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein MMR_HSR1 PF01926.23 KER28857.1 - 0.14 12.2 0.0 5.4 7.1 0.0 2.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-met PF12874.7 KER28859.1 - 2.8e-15 56.1 13.8 4e-05 23.8 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER28859.1 - 1.4e-12 47.6 10.8 0.00068 19.9 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding DZF PF07528.14 KER28859.1 - 3.8e-11 43.1 0.4 0.00022 20.9 0.0 4.2 3 1 0 3 3 3 3 DZF domain zf-C2H2_2 PF12756.7 KER28859.1 - 0.0037 17.6 9.1 1.7 9.0 0.0 3.5 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KER28859.1 - 5.6 7.2 13.3 3.5 7.8 0.1 3.4 3 0 0 3 3 3 0 DBF zinc finger DUF2185 PF09951.9 KER28861.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DUF1682 PF07946.14 KER28864.1 - 2.8e-91 306.1 0.0 4e-91 305.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) NINJA_B PF16136.5 KER28864.1 - 0.069 13.5 2.5 0.16 12.4 2.5 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal APC_15aa PF05972.11 KER28866.1 - 0.048 13.9 0.5 0.97 9.8 0.1 2.4 2 0 0 2 2 2 0 APC 15 residue motif DUF2550 PF10739.9 KER28868.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) M60-like_N PF17291.2 KER28870.1 - 2.6e-05 24.1 0.2 0.0041 17.0 0.0 2.2 1 1 1 2 2 2 2 N-terminal domain of M60-like peptidases SIM_C PF06621.12 KER28870.1 - 0.025 14.6 0.6 5.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Single-minded protein C-terminus FctA PF12892.7 KER28870.1 - 0.068 14.0 0.0 17 6.3 0.0 2.2 2 0 0 2 2 2 0 Spy0128-like isopeptide containing domain NCD2 PF04905.13 KER28870.1 - 0.096 12.7 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Rap1_C PF11626.8 KER28871.1 - 0.12 12.5 0.0 29 4.8 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 3-alpha PF03475.14 KER28871.1 - 4.3 7.3 8.1 21 5.1 1.1 2.9 3 0 0 3 3 3 0 3-alpha domain Sad1_UNC PF07738.13 KER28872.1 - 3e-34 117.9 0.0 6.9e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WD40 PF00400.32 KER28872.1 - 2.4e-14 53.5 17.1 9.7e-05 23.1 0.2 8.5 8 0 0 8 8 8 4 WD domain, G-beta repeat RVT_1 PF00078.27 KER28872.1 - 1.1e-11 44.7 0.1 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KER28872.1 - 3e-05 24.2 0.3 1.5 9.2 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF16 PF01519.16 KER28872.1 - 0.0027 18.2 0.9 0.0085 16.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 Fmp27_WPPW PF10359.9 KER28872.1 - 0.032 13.1 9.6 0.66 8.8 2.7 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 KER28872.1 - 0.051 13.6 14.2 0.44 10.6 0.8 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KER28872.1 - 1.4 9.3 4.8 1.3 9.4 0.2 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 rve PF00665.26 KER28873.1 - 2.8e-14 53.3 0.0 6.3e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 KER28873.1 - 0.0069 16.6 0.2 0.037 14.3 0.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KER28873.1 - 4.8 7.4 11.4 0.07 13.2 0.8 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-RanBP PF00641.18 KER28873.1 - 9.8 5.6 7.9 1.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others ERCC4 PF02732.15 KER28874.1 - 5.7e-20 72.1 0.0 2.8e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain HHH_2 PF12826.7 KER28874.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-C2H2_4 PF13894.6 KER28876.1 - 7.7e-22 76.1 74.0 0.0011 19.6 0.1 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.26 KER28876.1 - 4.6e-17 61.4 72.4 0.0005 20.4 0.4 9.5 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER28876.1 - 2.1e-13 50.0 53.1 0.02 15.3 0.2 10.1 10 1 0 10 10 10 5 Zinc-finger double domain zf-Di19 PF05605.12 KER28876.1 - 1.2e-09 38.3 44.2 9.9e-06 25.8 3.2 5.7 3 2 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KER28876.1 - 4.4e-08 32.9 56.2 0.0005 20.0 0.2 9.5 9 1 0 9 9 9 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KER28876.1 - 0.00024 21.1 25.9 0.59 10.3 2.0 6.2 5 2 1 6 6 6 3 Zinc ribbon domain zf-met PF12874.7 KER28876.1 - 0.0012 19.2 52.7 0.2 12.1 0.2 9.3 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KER28876.1 - 0.0079 16.1 47.6 0.23 11.4 1.1 8.0 9 0 0 9 9 8 4 zinc-finger of a C2HC-type DUF3268 PF11672.8 KER28876.1 - 0.031 14.6 13.9 0.73 10.2 0.2 4.4 4 1 1 5 5 5 0 zinc-finger-containing domain Elf1 PF05129.13 KER28876.1 - 0.076 13.1 26.3 0.83 9.7 1.5 5.2 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like zf-C2H2_3rep PF18868.1 KER28876.1 - 0.31 11.7 30.3 0.091 13.4 10.4 5.1 3 1 1 4 4 3 0 Zinc finger C2H2-type, 3 repeats RAG1_imp_bd PF12560.8 KER28876.1 - 0.44 10.0 13.3 1.1 8.7 0.1 3.7 3 1 1 4 4 4 0 RAG1 importin binding HypA PF01155.19 KER28876.1 - 0.8 9.8 22.0 7.1 6.7 2.8 5.0 1 1 3 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 KER28876.1 - 1.1 9.7 39.9 4.6 7.6 0.5 7.2 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KER28876.1 - 1.9 8.9 0.0 1.9 8.9 0.0 8.2 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KER28876.1 - 4.9 7.1 16.1 11 6.0 0.3 5.5 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) GDC-P PF02347.16 KER28877.1 - 4.4e-180 599.1 0.0 1.8e-172 574.0 0.0 3.0 3 1 0 3 3 3 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 KER28877.1 - 9.6e-06 24.4 0.2 2.2e-05 23.2 0.2 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KER28877.1 - 0.00027 20.3 0.1 0.00078 18.8 0.1 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KER28877.1 - 0.00061 18.9 0.0 0.026 13.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aldedh PF00171.22 KER28878.1 - 1.4e-79 267.8 0.0 1.7e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KER28878.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) VPS28 PF03997.12 KER28879.1 - 2.8e-15 56.5 1.0 4.1e-15 56.0 1.0 1.2 1 0 0 1 1 1 1 VPS28 protein Kazal_3 PF18434.1 KER28880.1 - 0.05 13.4 3.7 6 6.7 0.3 2.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Ntox1 PF15500.6 KER28880.1 - 0.075 13.4 1.8 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 TFIIS_M PF07500.14 KER28881.1 - 1.7e-45 154.1 1.3 2.6e-21 76.2 0.1 2.6 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KER28881.1 - 1.8e-11 43.9 1.6 1.8e-11 43.9 1.6 2.4 3 0 0 3 3 3 1 TFIIS helical bundle-like domain SLED PF12140.8 KER28881.1 - 0.007 16.9 0.0 11 6.6 0.0 3.1 3 0 0 3 3 3 2 SLED domain E1-E2_ATPase PF00122.20 KER28882.1 - 4.6e-50 169.7 3.1 4.7e-50 169.6 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KER28882.1 - 5.1e-44 150.2 5.6 5.1e-44 150.2 5.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KER28882.1 - 1.6e-16 61.2 0.0 1.4e-15 58.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KER28882.1 - 1.8e-15 56.4 0.0 3.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KER28882.1 - 3.5e-13 49.4 0.0 8.3e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KER28882.1 - 0.095 12.4 0.7 0.16 11.7 0.7 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPC12 PF06645.13 KER28882.1 - 0.68 10.1 2.2 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RINGv PF12906.7 KER28886.1 - 0.1 12.7 0.7 0.1 12.7 0.7 2.1 3 0 0 3 3 3 0 RING-variant domain MG2 PF01835.19 KER28890.1 - 0.0024 18.3 0.1 0.035 14.5 0.0 2.8 4 0 0 4 4 4 1 MG2 domain CdiI_3 PF18616.1 KER28890.1 - 0.011 15.6 0.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 CDI immunity proteins Cuticle_1 PF08140.11 KER28890.1 - 0.032 14.3 0.1 5.4 7.1 0.0 2.8 3 0 0 3 3 3 0 Crustacean cuticle protein repeat DUF3898 PF13037.6 KER28890.1 - 0.052 13.7 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) Triabin PF03973.13 KER28890.1 - 0.092 12.6 1.3 0.94 9.3 0.2 2.6 3 0 0 3 3 3 0 Triabin RMF PF04957.12 KER28893.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome modulation factor CBFD_NFYB_HMF PF00808.23 KER28894.1 - 2e-19 69.6 1.0 4e-19 68.7 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER28894.1 - 2.7e-13 50.4 1.7 7.3e-13 49.0 1.7 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KER28894.1 - 0.006 16.9 0.2 0.017 15.4 0.2 1.8 1 0 0 1 1 1 1 CENP-S associating Centromere protein X YuzL PF14115.6 KER28894.1 - 0.93 10.0 5.0 14 6.3 0.3 2.8 2 0 0 2 2 2 0 YuzL-like protein AAA PF00004.29 KER28896.1 - 6.9e-13 49.2 0.0 1.6e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER28896.1 - 1.4e-12 48.3 1.4 9.1e-12 45.7 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 KER28896.1 - 5.8e-12 45.4 0.0 1.2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 KER28896.1 - 1.4e-11 44.9 0.1 4e-11 43.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KER28896.1 - 3.4e-09 36.7 0.5 7.4e-09 35.6 0.5 1.5 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 KER28896.1 - 7.5e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KER28896.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KER28896.1 - 0.0027 17.1 0.1 0.0099 15.3 0.0 1.9 2 1 1 3 3 3 1 Bacterial TniB protein AAA_19 PF13245.6 KER28896.1 - 0.0071 16.7 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KER28896.1 - 0.053 13.9 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA C-terminal domain Phosphodiest PF01663.22 KER28897.1 - 1.1e-123 413.4 5.6 2.8e-61 208.1 0.7 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KER28897.1 - 2.4e-15 56.7 1.4 0.016 14.6 0.1 4.3 4 0 0 4 4 4 4 Sulfatase Metalloenzyme PF01676.18 KER28897.1 - 2e-08 33.9 0.0 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 2 Metalloenzyme superfamily Mito_carr PF00153.27 KER28897.1 - 2.6e-08 33.7 0.3 7.4e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 Mitochondrial carrier protein PglZ PF08665.12 KER28897.1 - 0.0019 18.3 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 PglZ domain LIM PF00412.22 KER28901.1 - 1.4e-06 28.5 5.2 3.3e-06 27.2 5.2 1.7 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.19 KER28901.1 - 1.1e-05 24.9 0.4 2.1e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KER28901.1 - 4.5e-05 22.8 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KER28901.1 - 5.7e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KER28901.1 - 7.2e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KER28901.1 - 8.6e-05 21.4 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KER28901.1 - 0.0021 18.2 0.0 0.0055 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KER28901.1 - 0.0036 16.4 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KER28901.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KER28901.1 - 0.0078 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KER28901.1 - 0.0083 16.7 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CH PF00307.31 KER28901.1 - 0.0097 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain FAD_oxidored PF12831.7 KER28901.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KER28901.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DZR PF12773.7 KER28901.1 - 4.7 7.3 6.6 9.2 6.4 1.9 2.9 2 0 0 2 2 2 0 Double zinc ribbon TAF4 PF05236.14 KER28902.1 - 5.4e-25 88.7 0.2 7.7e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 KER28902.1 - 1.2e-10 41.3 0.0 3.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 NHR1 homology to TAF ApoO PF09769.9 KER28904.1 - 4.2e-14 52.6 0.0 5.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O Tub PF01167.18 KER28905.1 - 8e-84 281.2 0.0 1.5e-83 280.2 0.0 1.5 1 0 0 1 1 1 1 Tub family Kri1 PF05178.12 KER28905.1 - 2.2 8.9 6.2 1.8 9.1 0.2 2.6 3 0 0 3 3 3 0 KRI1-like family Rhodopsin_N PF10413.9 KER28906.1 - 0.089 12.6 0.9 0.19 11.6 0.9 1.5 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin Nup188 PF10487.9 KER28907.1 - 2.2e-07 29.3 0.0 0.00039 18.5 0.0 2.6 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 FAM209 PF15206.6 KER28907.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 FAM209 family IF3_C PF00707.22 KER28909.1 - 0.061 13.3 0.1 0.24 11.4 0.1 2.1 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain gpW PF02831.15 KER28909.1 - 0.14 12.0 1.4 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 gpW LMP PF04778.12 KER28909.1 - 0.29 11.0 0.0 0.29 11.0 0.0 4.5 3 2 0 3 3 3 0 LMP repeated region PET PF06297.14 KER28909.1 - 0.68 10.3 5.1 0.98 9.8 0.7 3.0 2 0 0 2 2 2 0 PET Domain SNF2_N PF00176.23 KER28912.1 - 2.6e-53 181.0 0.0 5.8e-53 179.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER28912.1 - 8.7e-19 67.9 0.0 2.5e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRK PF07533.16 KER28912.1 - 1.5e-10 40.5 0.0 3.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 BRK domain Chromo PF00385.24 KER28912.1 - 1.3e-07 31.5 0.3 1.3e-07 31.5 0.3 4.5 4 1 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KER28912.1 - 6.6e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-bind_7 PF15963.5 KER28912.1 - 0.034 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Myb DNA-binding like PHTB1_C PF14728.6 KER28912.1 - 0.096 11.8 0.7 7.4 5.6 0.1 2.3 2 0 0 2 2 2 0 PTHB1 C-terminus RIIa PF02197.17 KER28914.1 - 4.7e-08 32.6 0.0 8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit cNMP_binding PF00027.29 KER28914.1 - 3.3e-06 27.1 0.0 8.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Herpes_capsid PF06112.11 KER28914.1 - 0.022 14.8 1.0 0.022 14.8 1.0 1.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Dpy-30 PF05186.13 KER28914.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif cNMP_binding PF00027.29 KER28915.1 - 1.8e-20 72.8 0.0 3.2e-20 72.0 0.0 1.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 KER28916.1 - 3.3e-08 33.5 0.0 3.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ge1_WD40 PF16529.5 KER28917.1 - 5.4e-43 147.2 0.0 4.2e-42 144.3 0.0 2.3 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KER28917.1 - 0.004 18.0 2.4 0.11 13.4 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat NDUF_B6 PF09782.9 KER28918.1 - 3.1e-14 53.4 0.1 6.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit RVT_1 PF00078.27 KER28918.1 - 1.5e-06 27.9 0.0 5.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DM PF00751.18 KER28920.1 - 7.2e-22 77.0 9.3 7.2e-22 77.0 9.3 1.9 2 0 0 2 2 2 1 DM DNA binding domain Dynein_light PF01221.18 KER28922.1 - 1.1e-40 137.8 2.9 1.2e-40 137.7 2.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phage_Gp111 PF07410.11 KER28922.1 - 0.027 14.9 0.6 0.031 14.7 0.6 1.1 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein Dynein_light PF01221.18 KER28923.1 - 6.9e-07 29.5 1.0 1.1e-06 28.8 1.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 NPP PF08384.10 KER28925.1 - 0.07 13.2 0.5 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region zf-C2H2 PF00096.26 KER28926.1 - 4.5e-14 52.0 22.7 2e-05 24.8 4.1 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER28926.1 - 6e-12 45.4 17.6 4.8e-07 29.9 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER28926.1 - 9.8e-09 35.3 20.4 0.00046 20.8 2.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER28926.1 - 0.00025 20.9 1.1 0.32 11.1 0.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KER28926.1 - 0.024 14.9 3.0 0.3 11.4 0.5 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KER28926.1 - 0.14 12.8 7.0 1 10.0 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KER28926.1 - 1.6 8.7 9.1 1.9 8.5 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type rve PF00665.26 KER28929.1 - 4.3e-05 23.7 0.0 9.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RRF PF01765.19 KER28930.1 - 0.53 10.2 3.1 0.43 10.5 0.8 2.0 2 1 1 3 3 3 0 Ribosome recycling factor DHHC PF01529.20 KER28932.1 - 1.4e-05 25.2 3.3 1.4e-05 25.2 3.3 3.5 3 1 1 4 4 4 2 DHHC palmitoyltransferase UPF0182 PF03699.13 KER28932.1 - 0.079 11.1 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) NOT2_3_5 PF04153.18 KER28934.1 - 7.4e-21 74.6 0.4 1.5e-20 73.6 0.4 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family SF3b10 PF07189.11 KER28935.1 - 8.6e-38 128.3 0.0 9.5e-38 128.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF1383 PF07134.11 KER28937.1 - 0.074 12.2 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) Cadherin PF00028.17 KER28938.1 - 1e-55 186.1 0.4 8.1e-14 51.8 0.0 8.7 7 2 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 KER28938.1 - 1.6 8.8 8.6 7.9 6.5 0.2 4.5 5 1 0 5 5 5 0 Cadherin-like zf-CCCH PF00642.24 KER28939.1 - 1.4e-13 50.3 29.0 3.3e-05 23.7 3.8 3.9 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER28939.1 - 3.4e-13 49.0 31.8 1.8e-07 30.8 2.0 4.3 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CHY PF05495.12 KER28939.1 - 2.5e-10 40.7 9.1 2.5e-10 40.7 9.1 4.8 4 0 0 4 4 4 1 CHY zinc finger zf_CCCH_4 PF18345.1 KER28939.1 - 2.7e-10 39.9 39.4 7.1e-06 25.9 5.7 4.3 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 KER28939.1 - 3.4e-05 24.5 15.6 0.05 14.3 0.3 3.6 1 1 2 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 KER28939.1 - 0.00091 19.6 33.9 0.0012 19.2 4.4 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KER28939.1 - 0.034 14.4 9.4 0.23 11.7 0.2 3.1 2 1 0 2 2 2 0 Zinc-finger containing family DUF1744 PF08490.12 KER28939.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Chibby PF14645.6 KER28941.1 - 1.8e-45 154.1 0.1 2.1e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Chibby family bZIP_1 PF00170.21 KER28941.1 - 0.1 12.7 2.5 0.3 11.2 1.5 2.2 3 0 0 3 3 3 0 bZIP transcription factor Tetraspanin PF00335.20 KER28942.1 - 3.1e-18 66.3 2.7 3.5e-18 66.2 2.7 1.0 1 0 0 1 1 1 1 Tetraspanin family G6PD_C PF02781.16 KER28943.1 - 1.1e-109 366.1 0.0 1.6e-109 365.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KER28943.1 - 9.1e-43 146.9 0.0 1.5e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MoCF_biosynth PF00994.24 KER28947.1 - 1.7e-48 164.0 0.0 8.3e-25 87.1 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KER28947.1 - 2.7e-34 118.2 0.0 4.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) ADH_zinc_N_2 PF13602.6 KER28947.1 - 4.4e-13 50.4 0.0 5.6e-12 46.9 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KER28947.1 - 9.4e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KER28947.1 - 0.0076 16.1 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TPR_11 PF13414.6 KER28947.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 TPR repeat adh_short PF00106.25 KER28947.1 - 0.2 11.1 0.0 0.88 9.0 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DEAD PF00270.29 KER28948.1 - 2.7e-46 157.5 0.2 4.4e-46 156.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER28948.1 - 3.6e-24 85.3 0.0 4.8e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KER28948.1 - 1.6e-12 47.4 0.1 3.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KER28948.1 - 3.7e-06 27.1 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KER28948.1 - 0.00028 20.3 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.6 KER28948.1 - 0.14 12.4 0.3 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain Enkurin PF13864.6 KER28949.1 - 5.1e-22 78.1 0.0 9.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Calmodulin-binding Ribosomal_S17 PF00366.20 KER28951.1 - 0.00061 19.9 0.2 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 DNA_pol3_beta_2 PF02767.16 KER28952.1 - 0.068 13.4 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Nrap PF03813.14 KER28953.1 - 0.0076 16.3 0.3 0.008 16.2 0.3 1.1 1 0 0 1 1 1 1 Nrap protein domain 1 HERV-K_REC PF15695.5 KER28953.1 - 0.052 13.6 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 S4_2 PF13275.6 KER28955.1 - 0.099 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 S4 domain IRF-3 PF10401.9 KER28957.1 - 3.2e-25 89.0 0.0 5.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.17 KER28957.1 - 4.2e-16 59.1 0.0 7.6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor MH2 PF03166.14 KER28957.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 MH2 domain Phytoreo_Pns PF05451.11 KER28957.1 - 0.054 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Pkinase PF00069.25 KER28958.1 - 1.2e-43 149.4 0.0 3.5e-43 147.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER28958.1 - 2e-15 56.8 0.0 3.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER28958.1 - 0.0034 16.8 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER28958.1 - 0.0054 16.1 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER28958.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KER28958.1 - 0.025 14.5 1.9 0.049 13.6 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER28958.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain p53-inducible11 PF14936.6 KER28960.1 - 4.7e-07 30.1 0.0 1.6e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Tumour protein p53-inducible protein 11 DUF4378 PF14309.6 KER28961.1 - 0.017 15.5 1.0 0.068 13.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4378) IQ PF00612.27 KER28963.1 - 0.00064 19.3 0.2 0.0024 17.5 0.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Fez1 PF06818.15 KER28963.1 - 0.0093 16.4 10.8 0.0093 16.4 10.8 6.1 2 2 2 4 4 4 1 Fez1 DUF3918 PF13056.6 KER28963.1 - 0.29 10.8 1.0 0.67 9.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Hydrolase_4 PF12146.8 KER28965.1 - 4.2e-15 55.7 0.1 1.9e-09 37.2 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KER28965.1 - 7.2e-13 48.8 0.4 6.9e-08 32.4 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER28965.1 - 3.6e-09 37.6 0.0 7.6e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KER28965.1 - 7.4e-07 28.9 0.1 0.019 14.4 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KER28965.1 - 0.00032 20.6 0.1 0.0015 18.3 0.0 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 KER28965.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.18 KER28965.1 - 0.054 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KER28965.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family WD40 PF00400.32 KER28966.1 - 2.4e-26 91.5 16.1 0.00027 21.7 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER28966.1 - 7e-09 35.9 1.7 0.0057 16.9 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER28966.1 - 0.00051 20.0 0.8 0.0038 17.1 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A FTO_CTD PF12934.7 KER28968.1 - 0.036 13.8 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 FTO C-terminal domain BLUF PF04940.12 KER28968.1 - 0.12 12.5 0.0 1.5 9.0 0.0 2.4 1 1 1 2 2 2 0 Sensors of blue-light using FAD CAP PF00188.26 KER28969.1 - 4.3e-13 50.2 0.0 4.3e-13 50.2 0.0 2.4 2 1 0 2 2 1 1 Cysteine-rich secretory protein family Endostatin PF06482.11 KER28969.1 - 5.1e-06 26.2 14.5 5.2e-06 26.2 14.5 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin SAPS PF04499.15 KER28969.1 - 0.00014 20.8 8.0 0.00014 20.8 8.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 KER28969.1 - 0.0013 17.2 2.7 0.0013 17.2 2.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SLC12 PF03522.15 KER28969.1 - 0.016 14.2 24.7 0.023 13.7 24.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 KER28969.1 - 0.047 12.6 10.9 0.074 12.0 10.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3807 PF12720.7 KER28969.1 - 0.21 11.8 37.3 2.8 8.2 39.9 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3807) Zip PF02535.22 KER28969.1 - 0.32 10.2 11.2 0.4 9.9 11.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KER28969.1 - 0.36 9.8 15.5 0.5 9.3 15.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LMBR1 PF04791.16 KER28969.1 - 0.37 9.7 9.3 0.37 9.6 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CBP_BcsG PF11658.8 KER28969.1 - 0.37 9.1 18.1 0.49 8.7 18.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Paf1 PF03985.13 KER28969.1 - 1.6 7.6 32.9 2.7 6.9 32.9 1.4 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 KER28969.1 - 1.7 7.3 39.6 2.4 6.9 39.6 1.1 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 KER28969.1 - 1.8 8.1 27.6 3.1 7.3 27.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Exonuc_VII_L PF02601.15 KER28969.1 - 1.9 7.9 26.7 2.5 7.6 26.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3292 PF11696.8 KER28969.1 - 2.7 6.3 27.9 3.6 5.8 27.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) BORG_CEP PF14957.6 KER28969.1 - 4.5 8.5 24.5 7.2 7.8 24.5 1.3 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.6 KER28969.1 - 5.2 7.0 24.6 8.4 6.3 24.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 KER28969.1 - 5.6 5.1 29.2 7.4 4.7 29.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 KER28969.1 - 5.9 5.2 28.1 7.7 4.8 28.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Gti1_Pac2 PF09729.9 KER28969.1 - 6.1 6.9 26.1 9.3 6.3 26.1 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family CCSAP PF15748.5 KER28969.1 - 6.7 6.8 45.6 8.7 6.4 45.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Paramyxo_ncap PF00973.19 KER28969.1 - 8.3 5.2 23.9 11 4.8 23.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Plasmodium_Vir PF05795.11 KER28969.1 - 9 5.6 16.9 12 5.2 16.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RRM_1 PF00076.22 KER28971.1 - 8.7e-59 195.3 0.0 9.1e-19 67.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA_2 PF13911.6 KER28971.1 - 2.9e-16 59.6 0.1 5.9e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme RRM_5 PF13893.6 KER28971.1 - 1.3e-10 41.0 0.0 0.00021 20.9 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA PF00578.21 KER28971.1 - 8.3e-07 29.0 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family RRM_occluded PF16842.5 KER28971.1 - 0.048 13.5 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF726 PF05277.12 KER28971.1 - 0.069 12.1 0.2 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) FYVE_2 PF02318.16 KER28973.1 - 0.003 17.7 1.5 0.003 17.7 1.5 1.8 2 1 0 2 2 2 1 FYVE-type zinc finger FYVE_2 PF02318.16 KER28974.1 - 2.9e-10 40.4 5.7 7.1e-10 39.1 5.7 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 KER28974.1 - 2.7e-05 24.2 9.8 0.0001 22.3 7.7 2.7 2 0 0 2 2 2 1 Piccolo Zn-finger zinc_ribbon_9 PF14369.6 KER28974.1 - 1 9.7 6.7 1.2 9.5 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon PHD PF00628.29 KER28974.1 - 3.3 7.7 10.0 9.7 6.2 10.0 1.9 1 0 0 1 1 1 0 PHD-finger C2 PF00168.30 KER28975.1 - 4.5e-21 75.1 0.0 9.4e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 KER28975.1 - 4.5e-07 29.6 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER28975.1 - 2.6e-06 27.7 0.1 5.7e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Corazonin PF17308.2 KER28975.1 - 0.26 11.7 3.0 0.21 11.9 0.3 2.2 2 0 0 2 2 2 0 Pro-corazonin RepB-RCR_reg PF10723.9 KER28977.1 - 0.46 10.4 2.5 0.83 9.6 0.4 2.4 1 1 2 3 3 3 0 Replication regulatory protein RepB CH_2 PF06294.11 KER28979.1 - 2.7e-20 72.3 0.0 4.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KER28979.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Ribosomal_S17e PF00833.18 KER28980.1 - 4e-55 185.0 0.4 4.9e-55 184.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 SIR2 PF02146.17 KER28982.1 - 2.5e-44 151.3 0.0 6.2e-44 150.0 0.0 1.7 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 KER28982.1 - 0.0013 17.8 0.1 0.023 13.6 0.1 2.0 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit Aminotran_5 PF00266.19 KER28985.1 - 1.1e-19 70.7 0.0 6.8e-10 38.4 0.0 2.4 1 1 1 2 2 2 2 Aminotransferase class-V ATP_bind_3 PF01171.20 KER28985.1 - 2.4e-10 40.5 0.0 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 PP-loop family DUF3958 PF13125.6 KER28986.1 - 0.021 15.0 0.5 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) GAT PF03127.14 KER28986.1 - 0.12 12.7 1.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 GAT domain MFS_1_like PF12832.7 KER28987.1 - 2.3e-42 145.3 20.0 2.9e-42 144.9 20.0 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KER28987.1 - 2.4e-07 30.0 50.8 8.6e-05 21.6 23.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KER28987.1 - 0.00092 18.3 1.3 0.00092 18.3 1.3 2.5 2 1 0 2 2 2 1 Nucleoside H+ symporter MFS_1_like PF12832.7 KER28988.1 - 6.7e-37 127.2 0.0 1.2e-36 126.4 0.0 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KER28988.1 - 8.7e-08 31.5 40.8 0.00019 20.5 19.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily E3_UbLigase_RBR PF18091.1 KER28990.1 - 0.0021 18.1 0.0 0.37 10.9 0.0 2.1 1 1 1 2 2 2 2 E3 Ubiquitin Ligase RBR C-terminal domain MlaD PF02470.20 KER28990.1 - 0.0028 17.9 0.3 1.9 8.8 0.0 2.1 1 1 1 2 2 2 2 MlaD protein MotA_ExbB PF01618.16 KER28990.1 - 0.0067 16.2 0.0 4.4 7.1 0.0 2.1 2 0 0 2 2 2 2 MotA/TolQ/ExbB proton channel family DUF2200 PF09966.9 KER28990.1 - 0.014 15.5 0.0 5.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF2073 PF09846.9 KER28990.1 - 0.023 14.6 0.0 5.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) DUF424 PF04242.13 KER28990.1 - 0.044 14.0 0.0 5.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF424) DUF5344 PF17279.2 KER28990.1 - 0.28 11.8 2.8 17 6.1 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5344) ATP-synt_S1 PF05827.12 KER28990.1 - 0.36 10.7 2.1 6.2 6.6 0.2 2.0 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Homeobox_KN PF05920.11 KER28993.1 - 4.5e-18 64.9 0.1 1e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KER28993.1 - 7.1e-07 29.0 0.0 2.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KER28993.1 - 0.6 10.7 12.5 1.8 9.1 1.8 3.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type SNAPc_SNAP43 PF09808.9 KER28997.1 - 1.3e-32 113.3 0.0 1.8e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Macoilin PF09726.9 KER28997.1 - 0.0054 15.3 0.3 0.0067 15.1 0.3 1.0 1 0 0 1 1 1 1 Macoilin family NAPRTase_N PF17767.1 KER28998.1 - 0.0046 17.3 1.7 0.0096 16.3 0.2 2.2 2 1 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Alpha_adaptin_C PF02296.16 KER28998.1 - 0.023 14.9 0.8 0.13 12.4 0.1 2.4 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain SelP_N PF04592.14 KER29000.1 - 0.1 12.0 10.5 0.12 11.7 10.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PDZ PF00595.24 KER29002.1 - 1.8e-13 50.6 0.0 3.3e-13 49.8 0.0 1.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KER29002.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KER29002.1 - 0.00071 19.8 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tyr_Deacylase PF02580.16 KER29003.1 - 4.3e-52 176.5 0.0 4.9e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF4487 PF14868.6 KER29004.1 - 8.6e-27 94.2 0.4 1e-26 93.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) Cullin PF00888.22 KER29007.1 - 5e-170 567.1 10.7 6.3e-170 566.8 10.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KER29007.1 - 3e-23 81.6 1.3 1e-22 79.9 1.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Dpy-30 PF05186.13 KER29007.1 - 0.017 14.8 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 Dpy-30 motif AraC_N PF06719.13 KER29007.1 - 0.049 13.3 0.5 4.1 7.0 0.1 2.6 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus GATase PF00117.28 KER29008.1 - 1.9e-30 106.1 0.0 3.9e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KER29008.1 - 1.4e-14 53.9 0.1 7.7e-11 41.9 0.0 3.7 3 2 0 3 3 3 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 KER29008.1 - 1.1e-08 35.1 0.3 6.7e-08 32.6 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KER29008.1 - 1.2e-08 34.4 0.1 0.0001 21.5 0.1 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 KER29008.1 - 1.3e-05 24.9 0.0 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KER29008.1 - 4.3e-05 23.2 0.1 0.0013 18.4 0.1 2.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KER29008.1 - 0.00017 20.5 0.2 0.00093 18.1 0.1 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 KER29008.1 - 0.00019 21.2 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 KER29008.1 - 0.004 16.9 0.1 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 PP-loop family RasGEF PF00617.19 KER29009.1 - 2e-15 57.4 0.3 6.7e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 KER29009.1 - 6.3e-05 23.2 0.0 0.00041 20.5 0.0 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Tom22 PF04281.13 KER29010.1 - 8.5e-11 41.8 0.1 1.1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DEAD PF00270.29 KER29011.1 - 1.4e-43 148.7 0.7 2.6e-43 147.8 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER29011.1 - 1.2e-24 86.8 0.1 5.4e-24 84.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain MULE PF10551.9 KER29011.1 - 2.5e-08 34.2 0.0 6.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain ResIII PF04851.15 KER29011.1 - 6.5e-07 29.5 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 KER29011.1 - 7.3e-06 26.1 0.1 2.5e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KER29011.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 KER29011.1 - 0.052 13.1 0.0 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 KER29011.1 - 0.3 10.4 6.8 0.46 9.8 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-C3H2C3 PF17122.5 KER29011.1 - 0.61 10.2 6.8 0.7 10.0 5.1 2.0 2 0 0 2 2 2 0 Zinc-finger Peptidase_A22B PF04258.13 KER29012.1 - 2.2e-60 204.6 6.0 3e-60 204.2 6.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase GSH_synth_ATP PF03917.17 KER29012.1 - 0.066 12.0 0.2 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Pterin_4a PF01329.19 KER29015.1 - 2.6e-30 104.4 0.0 2.9e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NIF PF03031.18 KER29016.1 - 8.6e-09 35.3 0.2 5.9e-08 32.6 0.2 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 KER29016.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Ndr PF03096.14 KER29017.1 - 5.8e-60 202.4 0.0 4.5e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_1 PF00561.20 KER29017.1 - 0.0086 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MPC PF03650.13 KER29018.1 - 4.1e-37 126.7 0.5 7.7e-37 125.8 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DMAP1 PF05499.12 KER29019.1 - 4.5e-47 160.0 7.5 1.4e-32 112.8 0.0 2.6 3 0 0 3 3 3 2 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 KER29019.1 - 6e-27 93.7 0.2 1.2e-26 92.7 0.2 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 RVT_1 PF00078.27 KER29020.1 - 2.6e-11 43.5 0.0 3.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1057 PF06342.12 KER29020.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2957 PF11170.8 KER29021.1 - 0.14 10.9 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) Trypsin PF00089.26 KER29022.1 - 8.9e-53 179.3 0.2 1.7e-29 103.2 0.0 2.5 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KER29022.1 - 2.4e-05 25.3 0.0 6.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-Tim10_DDP PF02953.15 KER29024.1 - 1.1e-12 47.4 6.1 1.4e-12 47.1 6.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4874 PF16173.5 KER29024.1 - 0.14 11.8 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DUF2116 PF09889.9 KER29024.1 - 0.53 10.3 4.5 1 9.4 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Usp PF00582.26 KER29025.1 - 6.5e-27 94.8 0.0 1e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 KER29026.1 - 1.7e-27 96.7 0.0 2.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family PPP5 PF08321.12 KER29027.1 - 0.091 13.1 0.1 15 6.0 0.0 2.2 1 1 1 2 2 2 0 PPP5 TPR repeat region GREB1 PF15782.5 KER29027.1 - 0.21 8.7 2.6 0.23 8.5 2.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4201 PF13870.6 KER29034.1 - 0.00036 20.3 13.3 0.00036 20.3 13.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) ThiD2 PF17792.1 KER29034.1 - 0.36 11.3 6.1 1.8 9.0 0.4 3.3 3 1 1 4 4 4 0 ThiD2 family DUF730 PF05325.11 KER29034.1 - 0.38 10.8 3.2 12 6.0 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF730) RrnaAD PF00398.20 KER29036.1 - 1.3e-59 201.4 0.0 1.6e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KER29036.1 - 8.3e-10 39.3 0.0 1.9e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER29036.1 - 1.9e-06 28.4 0.0 5.3e-06 27.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KER29036.1 - 3.1e-06 26.9 0.0 4.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KER29036.1 - 7e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER29036.1 - 1.6e-05 25.5 0.0 2.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KER29036.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KER29036.1 - 2.1e-05 24.4 0.0 4.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KER29036.1 - 0.00038 20.3 0.0 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 KER29036.1 - 0.00074 18.7 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 KER29036.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KER29036.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KER29036.1 - 0.0016 18.2 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein NodS PF05401.11 KER29036.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KER29036.1 - 0.0023 17.9 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 KER29036.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 KER29036.1 - 0.0068 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KER29036.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KER29036.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KER29036.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Spermine_synth PF01564.17 KER29036.1 - 0.066 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain CAT_RBD PF03123.15 KER29036.1 - 0.091 12.7 0.2 2.6 8.1 0.2 2.3 2 0 0 2 2 2 0 CAT RNA binding domain Methyltransf_PK PF05891.12 KER29036.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase tRNA_U5-meth_tr PF05958.11 KER29036.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_28 PF02636.17 KER29036.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase KH_1 PF00013.29 KER29037.1 - 4e-13 49.0 0.0 5.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KER29037.1 - 0.05 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 KH domain KLRAQ PF10205.9 KER29045.1 - 0.015 15.5 4.8 0.03 14.5 4.8 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Tropomyosin PF00261.20 KER29045.1 - 0.015 14.7 4.0 0.023 14.0 4.0 1.2 1 0 0 1 1 1 0 Tropomyosin YabA PF06156.13 KER29045.1 - 0.64 10.7 5.3 0.47 11.1 3.3 1.8 2 1 0 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 KER29045.1 - 3.4 8.2 8.0 0.31 11.5 1.8 2.3 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins ATP-synt_D PF01813.17 KER29046.1 - 1.2e-75 253.6 5.8 1.5e-75 253.3 5.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D ABC_tran PF00005.27 KER29048.1 - 1.2e-50 171.6 0.0 1.1e-24 87.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KER29048.1 - 6.2e-36 124.2 55.1 1.2e-28 100.3 24.9 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein RVT_1 PF00078.27 KER29048.1 - 1.3e-25 90.3 0.0 3.4e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_21 PF13304.6 KER29048.1 - 8.5e-19 68.5 6.9 2.9e-06 27.3 0.0 4.5 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KER29048.1 - 8.4e-05 23.2 0.6 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KER29048.1 - 0.00094 18.9 1.8 0.15 11.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 KER29048.1 - 0.0022 17.7 0.5 0.27 10.8 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KER29048.1 - 0.0066 16.4 0.1 0.24 11.3 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 KER29048.1 - 0.019 14.7 0.1 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 KER29048.1 - 0.045 13.0 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 KER29048.1 - 0.048 13.1 0.0 12 5.3 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 KER29048.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KER29048.1 - 0.15 12.4 0.0 8.3 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KER29048.1 - 0.17 11.9 0.1 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_13 PF13166.6 KER29048.1 - 0.19 10.4 0.0 0.19 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KER29048.1 - 0.19 11.4 0.2 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER29049.1 - 1.4e-53 181.0 0.0 5.4e-28 98.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KER29049.1 - 4.1e-22 79.4 0.2 1.7e-08 34.6 0.0 4.9 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KER29049.1 - 1.5e-21 76.9 18.9 1.5e-21 76.9 18.9 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 KER29049.1 - 2.3e-06 28.3 2.1 0.0086 16.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KER29049.1 - 7.6e-05 22.2 0.1 0.27 10.6 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KER29049.1 - 8.1e-05 22.3 1.0 0.005 16.5 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER29049.1 - 9.9e-05 22.3 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DUF4162 PF13732.6 KER29049.1 - 0.00086 20.0 0.0 0.048 14.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) MMR_HSR1 PF01926.23 KER29049.1 - 0.0021 18.1 0.1 0.96 9.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KER29049.1 - 0.0024 18.3 0.0 0.66 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KER29049.1 - 0.012 15.3 0.0 0.33 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 KER29049.1 - 0.029 13.6 14.5 0.06 12.6 14.2 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_22 PF13401.6 KER29049.1 - 0.074 13.3 0.0 20 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KER29049.1 - 0.089 13.0 0.0 44 4.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KER29049.1 - 0.15 11.7 1.1 7.5 6.1 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 KER29049.1 - 0.17 11.7 1.2 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_33 PF13671.6 KER29049.1 - 0.3 11.2 1.5 14 5.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain VIT1 PF01988.19 KER29049.1 - 0.86 9.4 3.5 2.6 7.9 3.5 1.8 1 0 0 1 1 1 0 VIT family TMEM43 PF07787.12 KER29049.1 - 6.5 6.1 8.5 12 5.2 8.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 CBM65_1 PF18259.1 KER29059.1 - 0.023 14.9 15.9 5 7.3 0.4 4.4 4 0 0 4 4 4 0 Carbohydrate binding module 65 domain 1 FragX_IP PF05994.11 KER29059.1 - 0.097 10.7 6.4 6 4.8 0.1 3.8 4 0 0 4 4 4 0 Cytoplasmic Fragile-X interacting family Adaptin_binding PF10199.9 KER29059.1 - 4 8.1 12.9 7.9 7.1 0.3 4.0 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 zf-TRAF PF02176.18 KER29060.1 - 2.7e-18 66.4 20.9 2.3e-11 44.2 7.3 4.0 3 1 1 4 4 3 2 TRAF-type zinc finger Sina PF03145.16 KER29060.1 - 1.6e-08 34.7 15.8 0.00064 19.7 1.4 3.0 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4 PF00097.25 KER29060.1 - 0.00031 20.5 5.6 0.00031 20.5 5.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER29060.1 - 0.00031 20.5 7.0 0.00031 20.5 7.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER29060.1 - 0.00051 19.8 6.0 0.00051 19.8 6.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KER29060.1 - 0.0048 16.7 2.4 0.0048 16.7 2.4 2.6 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-TRAF_2 PF15965.5 KER29060.1 - 0.048 14.1 24.7 0.14 12.6 5.9 3.7 1 1 2 3 3 3 0 TRAF-like zinc-finger DUF4470 PF14737.6 KER29060.1 - 0.056 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) DUF2024 PF09630.10 KER29060.1 - 0.56 10.1 4.0 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Presenilin PF01080.17 KER29060.1 - 1.1 8.0 8.6 1.5 7.5 8.6 1.1 1 0 0 1 1 1 0 Presenilin TRAF6_Z2 PF18048.1 KER29060.1 - 1.5 8.9 9.2 2.3 8.4 0.1 3.1 3 0 0 3 3 2 0 TNF receptor-associated factor 6 zinc finger 2 Zip PF02535.22 KER29060.1 - 4.6 6.4 8.1 6.3 5.9 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 KER29060.1 - 9.1 4.8 7.1 13 4.3 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mis12 PF05859.12 KER29061.1 - 5.2e-11 42.7 0.8 1.2e-10 41.6 0.3 1.7 1 1 1 2 2 2 1 Mis12 protein DHR10 PF18595.1 KER29061.1 - 0.089 12.9 2.9 0.11 12.6 1.3 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain RAMP4 PF06624.12 KER29062.1 - 7.3e-18 64.4 0.1 9.2e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Seadorna_Vp10 PF07322.11 KER29062.1 - 0.00099 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus Vp10 DUF1126 PF06565.12 KER29064.1 - 9.3e-69 227.9 0.0 9.3e-36 121.8 0.0 2.8 2 1 0 2 2 2 2 DUF1126 PH-like domain zf-Tim10_DDP PF02953.15 KER29066.1 - 2.7e-18 65.4 4.3 3.7e-18 64.9 4.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger YfkB PF08756.10 KER29067.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain Flot PF15975.5 KER29068.1 - 8.1e-09 35.7 55.9 1.6e-08 34.8 9.1 5.2 2 2 2 4 4 4 3 Flotillin Myofilin PF15929.5 KER29068.1 - 0.06 13.7 0.6 5.5 7.4 0.1 2.5 1 1 1 2 2 2 0 Myofilin Band_7 PF01145.25 KER29068.1 - 0.32 11.0 0.0 0.32 11.0 0.0 4.2 2 1 0 2 2 2 0 SPFH domain / Band 7 family DUF1223 PF06764.11 KER29068.1 - 3.3 7.7 11.1 0.28 11.2 4.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1223) zf-C4 PF00105.18 KER29069.1 - 8.7e-43 144.6 31.9 6.1e-23 81.1 11.6 2.7 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER29069.1 - 0.12 11.9 1.4 0.23 11.0 1.4 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.16 KER29069.1 - 0.38 11.1 17.7 0.049 13.9 1.5 4.3 4 0 0 4 4 4 0 C1 domain Transglut_core PF01841.19 KER29072.1 - 0.005 17.3 0.3 0.027 14.9 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 KER29072.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like domain Cyc-maltodext_N PF09087.11 KER29072.1 - 0.19 12.0 0.9 0.92 9.8 0.1 2.4 2 0 0 2 2 2 0 Cyclomaltodextrinase, N-terminal Cyclin_N PF00134.23 KER29073.1 - 2.9e-28 98.1 0.7 6.4e-28 97.0 0.7 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER29073.1 - 2.8e-07 30.7 0.2 2.8e-07 30.7 0.2 2.6 3 1 0 3 3 3 1 Cyclin, C-terminal domain Ldh_1_C PF02866.18 KER29075.1 - 4.6e-36 124.3 0.0 9.7e-36 123.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KER29075.1 - 6.5e-27 94.4 0.2 1.4e-26 93.3 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 KER29075.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF3585 PF12130.8 KER29076.1 - 3.6e-29 101.6 21.9 3.6e-29 101.6 21.9 1.8 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 KER29076.1 - 9.7e-19 67.6 0.0 2.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain NT-C2 PF10358.9 KER29076.1 - 3.3e-13 49.6 0.0 6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CAMSAP_CH PF11971.8 KER29076.1 - 5.1e-07 29.4 0.1 1.4e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 KER29076.1 - 0.011 15.8 0.0 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 CH-like domain in sperm protein 3-PAP PF12578.8 KER29076.1 - 7.6 6.3 9.2 4.1 7.2 0.1 3.7 3 1 1 4 4 4 0 Myotubularin-associated protein Telomere_Sde2_2 PF13297.6 KER29078.1 - 2.7e-25 87.8 0.0 6.1e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 KER29078.1 - 1.1e-21 77.4 0.7 1.1e-21 77.4 0.7 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Tom22 PF04281.13 KER29078.1 - 0.61 9.9 7.3 0.051 13.4 1.2 2.3 2 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ank_2 PF12796.7 KER29079.1 - 0.035 14.7 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) SOCS_box PF07525.16 KER29079.1 - 0.087 13.2 0.6 0.22 11.9 0.6 1.7 1 0 0 1 1 1 0 SOCS box GST_C_3 PF14497.6 KER29080.1 - 1e-15 57.7 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER29080.1 - 1.8e-10 41.0 0.0 3.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KER29080.1 - 9.4e-07 28.5 0.1 2.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER29080.1 - 1.4e-06 28.4 0.0 3.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER29080.1 - 6.8e-06 26.0 0.0 2.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KER29080.1 - 0.0017 18.7 0.1 0.0094 16.3 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain ANAPC4_WD40 PF12894.7 KER29082.1 - 3.3e-07 30.5 0.1 0.11 12.9 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER29082.1 - 9.8e-07 29.4 14.4 0.27 12.2 0.0 8.3 7 2 2 9 9 9 2 WD domain, G-beta repeat eIF2A PF08662.11 KER29082.1 - 1e-05 25.5 0.0 0.00074 19.4 0.0 3.6 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KER29082.1 - 0.34 8.9 0.5 5.5 4.8 0.1 2.4 2 1 0 3 3 3 0 IKI3 family PD40 PF07676.12 KER29082.1 - 0.6 10.1 3.8 13 5.9 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat GATA PF00320.27 KER29083.1 - 2.8e-41 138.8 35.4 1.3e-14 53.5 4.8 4.0 4 0 0 4 4 4 3 GATA zinc finger TF_Zn_Ribbon PF08271.12 KER29083.1 - 1.2e-08 34.3 12.8 0.019 14.5 0.7 3.5 3 0 0 3 3 3 3 TFIIB zinc-binding ArfGap PF01412.18 KER29083.1 - 5.6e-07 29.7 13.2 0.05 13.7 0.2 3.5 2 1 1 3 3 3 3 Putative GTPase activating protein for Arf Elf1 PF05129.13 KER29083.1 - 0.016 15.2 5.6 12 6.1 0.0 3.6 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.7 KER29083.1 - 0.024 14.6 13.1 11 6.1 1.1 3.8 1 1 1 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KER29083.1 - 0.03 14.2 12.2 1.8 8.5 0.7 3.4 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KER29083.1 - 0.039 14.1 12.1 5.6 7.2 0.5 3.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KER29083.1 - 0.047 13.8 7.3 18 5.5 0.3 3.7 3 0 0 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KER29083.1 - 0.086 12.6 11.5 55 3.6 0.0 5.6 5 1 0 5 5 5 0 A2L zinc ribbon domain Prok-RING_2 PF14445.6 KER29083.1 - 5.1 7.3 13.5 1.1 9.5 0.4 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Prim_Zn_Ribbon PF08273.12 KER29083.1 - 7 7.0 22.0 3.1 8.1 1.5 4.3 3 1 1 4 4 4 0 Zinc-binding domain of primase-helicase CBP PF12192.8 KER29084.1 - 1.2 9.4 8.1 7.1 6.9 2.2 2.3 1 1 1 2 2 2 0 Fungal calcium binding protein Med7 PF05983.11 KER29085.1 - 1.5e-38 132.8 7.6 1.5e-38 132.8 5.3 1.9 2 1 0 2 2 2 1 MED7 protein EppA_BapA PF07268.11 KER29085.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) PAP2 PF01569.21 KER29086.1 - 1e-16 60.9 7.7 1e-16 60.9 7.7 2.3 2 1 0 2 2 2 1 PAP2 superfamily BC10 PF06726.12 KER29086.1 - 0.046 14.0 0.1 0.046 14.0 0.1 3.0 4 0 0 4 4 4 0 Bladder cancer-related protein BC10 HlyIII PF03006.20 KER29087.1 - 4.2e-46 157.5 30.1 6e-44 150.4 30.1 2.2 1 1 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KER29087.1 - 0.00066 19.7 1.2 0.026 14.6 1.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) YrhK PF14145.6 KER29087.1 - 0.12 12.3 9.3 0.71 9.8 0.2 4.0 4 0 0 4 4 4 0 YrhK-like protein CLP1_P PF16575.5 KER29089.1 - 5.3e-30 104.6 0.0 9.4e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KER29089.1 - 0.0043 17.4 0.0 0.0091 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KER29089.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KER29089.1 - 0.053 13.6 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER29089.1 - 0.069 13.7 0.0 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 KER29089.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KER29089.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KER29089.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glycolytic PF00274.19 KER29090.1 - 2.1e-174 579.2 0.0 2.5e-174 579.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Pkinase PF00069.25 KER29090.1 - 2.6e-40 138.5 0.0 4.1e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29090.1 - 9.5e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER29090.1 - 0.00013 20.9 0.0 0.00031 19.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase F-box-like PF12937.7 KER29091.1 - 9.3e-06 25.4 1.4 3.6e-05 23.6 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box_5 PF18511.1 KER29091.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box NifQ PF04891.12 KER29091.1 - 0.079 13.3 0.3 0.18 12.2 0.3 1.7 1 0 0 1 1 1 0 NifQ tRNA-synt_2e PF02091.15 KER29092.1 - 0.0034 16.7 0.2 0.058 12.6 0.0 2.3 2 0 0 2 2 2 1 Glycyl-tRNA synthetase alpha subunit Acetyltransf_16 PF05301.11 KER29092.1 - 0.094 12.5 2.6 0.91 9.3 0.4 2.3 2 0 0 2 2 2 0 GNAT acetyltransferase, Mec-17 Glyco_transf_9 PF01075.17 KER29094.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) TMEM132 PF16070.5 KER29095.1 - 1.1e-17 64.4 0.0 7.8e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 Transmembrane protein family 132 TMEM132D_C PF15706.5 KER29095.1 - 1.2e-06 28.2 0.2 6.7e-06 25.8 0.2 2.2 1 1 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pkinase_Tyr PF07714.17 KER29096.1 - 4.1e-54 183.6 0.0 5.9e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER29096.1 - 3.9e-53 180.5 0.0 5.5e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.15 KER29096.1 - 2.2e-18 66.1 0.0 4.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 KER29096.1 - 6.1e-08 32.4 9.2 6.1e-08 32.4 9.2 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KER29096.1 - 0.0014 18.5 4.0 0.0014 18.5 4.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 ADK_lid PF05191.14 KER29096.1 - 0.0067 16.4 2.9 0.01 15.8 0.2 2.3 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf-RING-like PF08746.11 KER29096.1 - 0.015 15.6 5.5 0.015 15.6 5.5 2.5 2 0 0 2 2 2 0 RING-like domain APH PF01636.23 KER29096.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.22 KER29098.1 - 3.2e-20 72.9 0.1 6.6e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KER29098.1 - 3.9e-17 62.7 0.0 2.4e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KER29098.1 - 0.034 13.3 0.3 0.11 11.6 0.1 1.7 1 1 0 2 2 2 0 Rgp1 PH_12 PF16457.5 KER29100.1 - 1.7e-08 35.1 1.1 6.1e-06 26.8 1.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_14 PF17787.1 KER29100.1 - 0.011 15.6 0.0 3.1 7.7 0.0 2.1 2 0 0 2 2 2 0 PH domain PH PF00169.29 KER29100.1 - 0.015 15.8 0.1 0.39 11.3 0.1 2.3 1 1 0 1 1 1 0 PH domain Mcp5_PH PF12814.7 KER29100.1 - 0.033 14.3 0.2 3.2 7.9 0.1 2.3 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF4880 PF16220.5 KER29100.1 - 0.17 11.8 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) PI-PLC-X PF00388.19 KER29101.1 - 1e-31 109.5 0.0 4.8e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KER29101.1 - 4.7e-26 91.4 0.0 1.4e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KER29101.1 - 1.6e-09 38.0 0.0 5.5e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF4756 PF15948.5 KER29104.1 - 0.052 13.4 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) CBFB_NFYA PF02045.15 KER29105.1 - 4.3e-28 97.7 8.1 6.5e-28 97.1 8.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KER29105.1 - 0.81 9.6 13.4 0.99 9.3 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone_H2A_C PF16211.5 KER29107.1 - 6.8e-20 70.5 0.5 1.1e-19 69.8 0.5 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KER29107.1 - 3.9e-11 43.4 0.0 4.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER29107.1 - 0.035 14.4 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cyclin_N PF00134.23 KER29108.1 - 3.3e-36 123.8 0.2 5.7e-36 123.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER29108.1 - 2.1e-22 79.4 1.2 1.5e-21 76.7 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain SKIP_SNW PF02731.15 KER29111.1 - 6.3e-66 221.0 3.4 6.3e-66 221.0 3.4 3.8 3 1 0 3 3 3 1 SKIP/SNW domain I_LWEQ PF01608.17 KER29113.1 - 3.6e-44 150.7 3.0 3.6e-44 150.7 3.0 3.1 3 0 0 3 3 3 1 I/LWEQ domain ANTH PF07651.16 KER29113.1 - 4.1e-38 130.9 1.0 8.6e-38 129.9 0.0 1.9 2 0 0 2 2 2 1 ANTH domain Sigma70_ner PF04546.13 KER29113.1 - 0.24 11.2 8.0 1.1 9.0 7.1 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region Jnk-SapK_ap_N PF09744.9 KER29113.1 - 1.9 8.7 27.8 0.15 12.2 10.6 4.0 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 CCDC-167 PF15188.6 KER29113.1 - 4.4 7.7 15.1 0.8 10.1 0.4 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 CENP-F_leu_zip PF10473.9 KER29113.1 - 9.8 6.2 29.3 0.021 14.8 16.9 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arm PF00514.23 KER29115.1 - 8.4e-27 92.3 18.1 1.3e-07 31.4 0.2 8.9 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KER29115.1 - 4.4e-05 23.8 3.7 5.8 7.4 0.0 5.6 4 1 1 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 KER29115.1 - 0.00013 20.7 5.6 0.0032 16.1 1.5 3.0 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 KER29115.1 - 0.00048 20.2 4.3 5.9 7.4 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat KAP PF05804.12 KER29115.1 - 0.0039 15.4 1.6 0.027 12.7 1.6 2.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 KER29115.1 - 0.0077 16.7 7.2 22 5.7 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat Arm_2 PF04826.13 KER29115.1 - 0.012 15.0 2.0 0.7 9.3 0.0 3.0 2 1 2 4 4 4 0 Armadillo-like RasGEF_N_2 PF14663.6 KER29115.1 - 0.077 13.4 1.1 20 5.6 0.2 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Drf_GBD PF06371.13 KER29115.1 - 4.4 6.8 4.7 2.3 7.7 0.1 2.6 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain Cellulase PF00150.18 KER29116.1 - 9.6e-31 107.2 0.5 1.3e-30 106.8 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KER29116.1 - 5.4e-08 33.3 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain HpuA PF16960.5 KER29116.1 - 0.044 12.9 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter Cellulase PF00150.18 KER29117.1 - 5.3e-32 111.4 0.0 8.5e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KER29117.1 - 8.9e-08 32.6 0.0 1.8e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KER29117.1 - 0.039 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF1731 PF08338.11 KER29119.1 - 9.2e-21 73.4 0.1 2.8e-20 71.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KER29119.1 - 3.4e-08 33.3 0.0 1.7e-05 24.5 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KER29119.1 - 0.00014 21.8 0.1 0.00099 19.0 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KER29119.1 - 0.0016 18.1 0.2 0.0027 17.3 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family Flavodoxin_3 PF12641.7 KER29119.1 - 0.0053 16.5 0.0 3.1 7.5 0.0 2.3 1 1 1 2 2 2 2 Flavodoxin domain ApbA PF02558.16 KER29119.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KER29119.1 - 0.041 14.5 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Torsin PF06309.11 KER29119.1 - 0.057 13.5 0.0 8.5 6.5 0.0 2.6 1 1 1 2 2 2 0 Torsin GDP_Man_Dehyd PF16363.5 KER29119.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase HTH_33 PF13592.6 KER29119.1 - 0.11 12.2 0.1 26 4.6 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix NAD_binding_2 PF03446.15 KER29119.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KER29119.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tup_N PF08581.10 KER29120.1 - 0.0012 19.2 4.0 0.085 13.2 0.3 3.0 3 0 0 3 3 3 2 Tup N-terminal Fib_alpha PF08702.10 KER29120.1 - 0.013 15.7 7.0 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KER29120.1 - 0.016 14.8 9.6 0.068 12.7 9.2 2.0 2 0 0 2 2 2 0 Intermediate filament protein DASH_Dad3 PF08656.10 KER29120.1 - 0.025 14.7 1.9 0.066 13.3 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 Spc7 PF08317.11 KER29120.1 - 0.1 11.4 13.7 0.14 11.0 11.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 KER29120.1 - 0.17 12.3 3.4 0.42 11.0 3.4 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Cir_Bir_Yir PF06022.11 KER29120.1 - 0.18 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Myosin_tail_1 PF01576.19 KER29120.1 - 0.35 8.6 14.3 1.6 6.4 14.2 1.7 1 1 0 1 1 1 0 Myosin tail BLOC1_2 PF10046.9 KER29120.1 - 4.4 7.7 7.0 1.4 9.2 0.7 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 KER29120.1 - 5.7 7.3 8.1 6.3 7.1 1.6 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein SH3_1 PF00018.28 KER29122.1 - 4.1e-39 131.9 0.1 7e-12 44.8 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 KER29122.1 - 3.1e-33 113.4 0.0 1e-09 38.1 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH2 PF00017.24 KER29122.1 - 7.4e-30 102.9 0.0 7.2e-18 64.5 0.0 2.4 2 0 0 2 2 2 2 SH2 domain SH3_2 PF07653.17 KER29122.1 - 1.2e-25 89.0 0.0 2.1e-07 30.5 0.0 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 KER29122.1 - 3.6e-05 24.0 0.0 4.1 7.8 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain DUF3206 PF11472.8 KER29122.1 - 0.0044 17.0 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3206) Glyco_hydro_63N PF16923.5 KER29122.1 - 0.079 13.0 0.0 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain Cbl_N3 PF02762.14 KER29122.1 - 0.13 12.2 0.0 17 5.4 0.0 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Mhr1 PF12829.7 KER29123.1 - 0.012 15.7 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination PI3K_P85_iSH2 PF16454.5 KER29125.1 - 0.00087 18.9 15.3 0.04 13.5 5.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atg14 PF10186.9 KER29125.1 - 0.026 13.6 8.7 0.035 13.2 8.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KER29125.1 - 0.042 12.7 16.3 0.052 12.4 15.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Tweety PF04906.13 KER29125.1 - 0.11 11.1 2.3 0.15 10.7 2.3 1.1 1 0 0 1 1 1 0 Tweety SlyX PF04102.12 KER29125.1 - 0.18 12.4 16.3 1.2 9.8 4.1 3.3 1 1 2 3 3 3 0 SlyX Nucleoporin_FG2 PF15967.5 KER29125.1 - 0.21 10.1 2.7 0.27 9.7 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region V_ATPase_I PF01496.19 KER29125.1 - 0.28 9.0 9.3 0.35 8.7 9.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KER29125.1 - 0.37 11.2 3.7 17 5.9 0.2 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) USP8_interact PF08941.10 KER29125.1 - 0.42 10.4 9.8 0.13 12.0 1.2 2.1 2 0 0 2 2 2 0 USP8 interacting Phlebovirus_NSM PF07246.11 KER29125.1 - 0.57 9.5 5.9 0.99 8.7 5.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Fez1 PF06818.15 KER29125.1 - 0.63 10.5 15.0 14 6.1 15.0 2.0 1 1 0 1 1 1 0 Fez1 DUF3287 PF11690.8 KER29125.1 - 0.64 9.8 5.8 0.54 10.0 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) ATG16 PF08614.11 KER29125.1 - 0.81 9.9 18.8 2.5 8.3 6.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KER29125.1 - 1 9.7 12.0 4.3 7.7 8.8 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 KER29125.1 - 1.1 7.8 6.9 1.3 7.6 6.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF641 PF04859.12 KER29125.1 - 1.8 8.9 12.3 23 5.4 12.2 2.2 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 KER29125.1 - 1.8 8.0 9.5 2.4 7.6 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 KER29125.1 - 2.5 8.3 13.6 2.4 8.3 8.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 KER29125.1 - 3.3 8.0 16.0 8.5 6.7 7.6 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF948 PF06103.11 KER29125.1 - 3.6 7.9 5.8 19 5.6 2.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GPS2_interact PF15784.5 KER29125.1 - 3.8 8.0 9.6 4.1 7.9 0.4 2.5 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF3552 PF12072.8 KER29125.1 - 6.3 6.2 19.8 2.9 7.3 13.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) C2 PF00168.30 KER29126.1 - 2e-17 63.3 0.0 8.1e-11 42.1 0.0 2.9 3 0 0 3 3 3 2 C2 domain LRR_8 PF13855.6 KER29127.1 - 2.2e-39 133.0 22.3 2.9e-11 43.0 3.8 6.1 6 0 0 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 KER29127.1 - 3.3e-17 62.3 14.5 3e-05 24.3 0.5 5.9 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KER29127.1 - 5e-13 49.1 0.0 1.7e-07 31.2 0.0 2.9 2 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KER29127.1 - 1.6e-08 33.9 20.8 0.56 11.0 0.1 9.2 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KER29127.1 - 0.0022 17.9 20.3 3.4 7.9 0.1 8.2 10 0 0 10 10 10 2 Leucine Rich repeat LRR_9 PF14580.6 KER29127.1 - 0.0032 17.0 3.3 1.4 8.4 0.2 3.2 2 1 1 3 3 3 2 Leucine-rich repeat PRIMA1 PF16101.5 KER29127.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF1744 PF08490.12 KER29128.1 - 2.9e-96 322.5 0.0 7.5e-96 321.1 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KER29128.1 - 1.6e-60 205.1 0.0 2.5e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Zip PF02535.22 KER29128.1 - 3.8e-23 82.2 1.7 6e-23 81.6 1.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DNA_pol_B PF00136.21 KER29128.1 - 1.9e-11 43.4 0.1 9.7e-11 41.0 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KER29128.1 - 1.9e-08 34.3 0.0 5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KER29128.1 - 0.00072 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DUF4203 PF13886.6 KER29128.1 - 0.23 11.1 9.1 2.5 7.7 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) zinc_ribbon_4 PF13717.6 KER29128.1 - 7 6.7 14.7 5.6 7.0 0.2 4.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF1759 PF03564.15 KER29130.1 - 3.6e-10 39.9 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) SecM PF06558.12 KER29130.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) Mak10 PF04112.13 KER29131.1 - 9.9e-20 70.7 0.2 1.2e-18 67.1 0.2 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TMCO5 PF14992.6 KER29132.1 - 0.025 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF2721 PF11026.8 KER29132.1 - 0.055 13.4 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) PDR_assoc PF08370.11 KER29132.1 - 0.18 11.5 0.6 0.48 10.2 0.6 1.6 1 0 0 1 1 1 0 Plant PDR ABC transporter associated BCAS2 PF05700.11 KER29133.1 - 1.6e-72 243.6 2.2 1.8e-72 243.4 2.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Golgin_A5 PF09787.9 KER29133.1 - 0.011 15.3 3.6 0.023 14.2 3.5 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3090 PF11290.8 KER29133.1 - 0.16 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DUF4140 PF13600.6 KER29133.1 - 0.19 12.2 0.8 20 5.7 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.21 KER29133.1 - 0.2 12.1 8.4 2.5 8.6 2.8 2.3 1 1 0 2 2 2 0 Spectrin repeat MetOD2 PF18548.1 KER29133.1 - 0.58 10.3 5.0 14 5.9 0.1 3.0 3 1 1 4 4 4 0 Metanogen output domain 2 Csm1_N PF18504.1 KER29133.1 - 1.6 9.1 5.2 1.5 9.2 1.8 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain wnt PF00110.19 KER29136.1 - 1.5e-109 366.3 16.4 2.3e-109 365.7 16.4 1.3 1 0 0 1 1 1 1 wnt family Metallophos PF00149.28 KER29137.1 - 1.8e-24 87.4 0.0 3.7e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IQ PF00612.27 KER29137.1 - 0.54 10.2 5.3 0.098 12.5 0.5 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif SAMP PF05924.11 KER29137.1 - 0.7 9.3 4.2 5.4 6.4 0.0 2.7 2 0 0 2 2 2 0 SAMP Motif ANAPC1 PF12859.7 KER29138.1 - 0.0053 17.3 0.0 0.0053 17.3 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KER29138.1 - 5.7 7.6 23.5 0.66 10.5 2.7 5.9 6 0 0 6 6 6 0 Proteasome/cyclosome repeat WD40 PF00400.32 KER29139.1 - 3.3e-11 43.6 10.6 0.0021 18.8 2.3 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat WD40 PF00400.32 KER29140.1 - 0.00058 20.6 0.6 0.0031 18.3 0.5 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat hEGF PF12661.7 KER29141.1 - 0.0054 17.3 1.0 5.3 7.8 0.1 2.6 2 0 0 2 2 2 2 Human growth factor-like EGF DUF1816 PF08846.10 KER29141.1 - 0.014 15.4 2.0 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) LST1 PF05083.13 KER29141.1 - 0.014 15.6 1.0 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 LST-1 protein DUF2769 PF10967.8 KER29141.1 - 0.018 15.7 2.2 6.6 7.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) AdenylateSensor PF16579.5 KER29141.1 - 0.03 14.8 0.0 0.083 13.3 0.0 1.7 2 0 0 2 2 2 0 Adenylate sensor of SNF1-like protein kinase RMP PF14996.6 KER29141.1 - 0.095 12.9 2.0 9.4 6.4 0.2 2.2 2 0 0 2 2 2 0 Retinal Maintenance Leu_leader PF08054.11 KER29141.1 - 0.13 11.9 0.1 22 4.7 0.0 2.4 2 0 0 2 2 2 0 Leucine operon leader peptide Toxin_11 PF07473.11 KER29141.1 - 0.4 10.8 5.9 8.7 6.5 0.6 2.4 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species I-set PF07679.16 KER29143.1 - 8.5e-07 29.0 0.0 2.3e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 KER29143.1 - 2.8e-05 24.2 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 KER29143.1 - 7.5e-05 23.2 0.0 0.00026 21.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER29143.1 - 0.00019 21.7 0.0 0.00061 20.1 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER29143.1 - 0.00021 21.4 0.0 0.00082 19.5 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 KER29143.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF446 PF04287.12 KER29144.1 - 0.0045 17.0 0.1 0.0071 16.4 0.1 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase C TTL PF03133.15 KER29145.1 - 3.5e-59 200.4 0.7 6.1e-59 199.6 0.7 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ANAPC3 PF12895.7 KER29146.1 - 0.00012 22.2 0.1 0.00032 20.9 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2 PF00096.26 KER29147.1 - 0.022 15.2 0.4 0.064 13.7 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DnaJ PF00226.31 KER29148.1 - 9.1e-23 80.2 0.2 2.6e-22 78.7 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KER29148.1 - 6.3e-13 48.6 3.4 1.3e-09 38.0 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER29148.1 - 1.5e-08 34.7 4.1 2.5e-05 24.5 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KER29148.1 - 2.5e-07 31.0 0.4 0.027 14.8 0.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KER29148.1 - 0.0032 18.2 0.6 1.3 10.0 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-DBF PF07535.12 KER29148.1 - 0.024 14.7 1.0 1.5 9.0 0.2 2.5 2 0 0 2 2 2 0 DBF zinc finger Tom5 PF10642.9 KER29148.1 - 0.042 13.9 1.8 0.082 13.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase zf-C2H2 PF00096.26 KER29148.1 - 0.25 11.9 1.8 10 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Homeobox_KN PF05920.11 KER29150.1 - 1.2e-15 57.1 0.5 3.4e-15 55.7 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KER29150.1 - 1.6e-05 24.6 1.8 2.4e-05 24.1 0.6 1.9 2 0 0 2 2 2 1 Homeodomain PX PF00787.24 KER29152.1 - 2e-23 82.5 0.0 3.2e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 PX domain Lactamase_B PF00753.27 KER29153.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Methyltransf_11 PF08241.12 KER29156.1 - 9.3e-12 45.4 0.0 3.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER29156.1 - 1.7e-11 44.6 0.0 2.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER29156.1 - 3.6e-07 30.8 0.0 5.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER29156.1 - 2.2e-06 27.5 0.0 1.8e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER29156.1 - 1.9e-05 24.6 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KER29156.1 - 5.2e-05 22.7 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KER29156.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KER29156.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NUDIX_2 PF13869.6 KER29157.1 - 5.5e-73 244.6 0.0 6.3e-73 244.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 KER29157.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain RVT_1 PF00078.27 KER29159.1 - 2.1e-39 135.3 0.1 1.6e-38 132.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin PF00804.25 KER29159.1 - 0.007 16.1 8.0 1.9 8.1 6.6 2.4 2 0 0 2 2 2 2 Syntaxin Cep3 PF16846.5 KER29159.1 - 0.047 12.2 0.3 0.095 11.2 0.3 1.4 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B KxDL PF10241.9 KER29159.1 - 2.4 8.5 8.9 1.2 9.5 0.1 3.7 3 1 0 4 4 4 0 Uncharacterized conserved protein Ribosomal_L44 PF00935.19 KER29160.1 - 2.8e-35 120.6 12.9 4.1e-35 120.1 12.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RNA_POL_M_15KD PF02150.16 KER29160.1 - 0.033 14.1 0.8 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit LRV_FeS PF05484.11 KER29160.1 - 0.16 12.0 4.5 1.5 8.9 0.3 2.2 2 0 0 2 2 2 0 LRV protein FeS4 cluster Pkinase PF00069.25 KER29163.1 - 6e-05 22.5 0.1 8.6e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29163.1 - 0.061 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Brix PF04427.18 KER29164.1 - 3.6e-24 85.9 0.1 4.7e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain CPL PF08144.11 KER29166.1 - 8.9e-11 42.3 0.1 8.5e-10 39.1 0.1 2.5 2 0 0 2 2 2 1 CPL (NUC119) domain TBP PF00352.21 KER29167.1 - 3.7e-35 119.7 0.1 3.4e-19 68.6 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) RRM_1 PF00076.22 KER29168.1 - 6.4e-36 122.0 0.1 3e-17 62.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM_int_assoc PF16605.5 KER29168.1 - 0.00029 20.9 4.8 0.00099 19.2 4.8 2.0 1 1 0 1 1 1 1 LSM-interacting associated unstructured Lsm_interact PF05391.11 KER29168.1 - 0.0016 17.8 0.9 0.0016 17.8 0.9 2.0 2 0 0 2 2 2 1 Lsm interaction motif Mad3_BUB1_I PF08311.12 KER29168.1 - 0.0052 16.8 2.9 8.7 6.3 0.0 4.7 5 0 0 5 5 5 1 Mad3/BUB1 homology region 1 RRM_5 PF13893.6 KER29168.1 - 0.0093 15.6 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 KER29168.1 - 0.01 16.6 10.5 1.5 9.9 0.9 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_occluded PF16842.5 KER29168.1 - 0.011 15.5 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif RVT_1 PF00078.27 KER29169.1 - 3.5e-09 36.5 0.0 5.4e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuclease_3 PF00636.26 KER29170.1 - 6.5e-57 190.6 0.1 3e-32 111.3 0.0 3.3 3 1 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.22 KER29170.1 - 4.6e-32 110.7 0.0 9.4e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.14 KER29170.1 - 1.2e-21 76.7 0.0 3.3e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KER29170.1 - 5.3e-20 71.9 0.0 3.7e-10 40.0 0.0 4.2 4 0 0 4 4 4 2 Ribonuclease-III-like Helicase_C PF00271.31 KER29170.1 - 0.00012 22.4 0.0 0.00034 20.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.27 KER29170.1 - 0.00039 20.0 0.0 0.00094 18.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adaptin_N PF01602.20 KER29173.1 - 4.9e-107 358.7 5.9 2.7e-94 316.6 2.6 3.1 2 1 1 3 3 3 2 Adaptin N terminal region AP3D1 PF06375.11 KER29173.1 - 1.2e-36 126.4 4.8 1.2e-36 126.4 4.8 2.7 2 1 1 3 3 3 1 AP-3 complex subunit delta-1 Cnd1 PF12717.7 KER29173.1 - 4.3e-15 56.1 0.9 7.7e-10 39.0 0.0 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KER29173.1 - 8.1e-06 26.1 0.0 0.03 14.7 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KER29173.1 - 9.4e-06 25.5 0.1 0.73 10.2 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 KER29173.1 - 0.00065 19.9 3.4 0.54 10.5 0.0 3.2 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF1804 PF08822.11 KER29173.1 - 0.044 13.8 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) RasGEF_N_2 PF14663.6 KER29173.1 - 0.1 13.0 0.2 14 6.2 0.1 3.4 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TYA PF01021.19 KER29173.1 - 0.13 12.6 3.9 0.49 10.8 3.9 2.0 1 0 0 1 1 1 0 TYA transposon protein DUF2120 PF09893.9 KER29173.1 - 0.43 10.7 3.3 27 4.9 0.1 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) V-ATPase_H_C PF11698.8 KER29173.1 - 0.46 10.6 3.0 4.6 7.4 0.1 3.6 2 2 2 4 4 4 0 V-ATPase subunit H EntA_Immun PF08951.10 KER29173.1 - 0.87 10.0 3.8 36 4.8 0.1 3.8 2 1 1 3 3 3 0 Enterocin A Immunity SRP54_N PF02881.19 KER29173.1 - 4.9 7.5 5.9 40 4.5 0.1 3.4 4 0 0 4 4 4 0 SRP54-type protein, helical bundle domain PQ-loop PF04193.14 KER29174.1 - 0.0017 18.1 1.0 0.0048 16.6 1.0 1.8 1 0 0 1 1 1 1 PQ loop repeat fn3 PF00041.21 KER29175.1 - 3.3e-32 110.7 4.7 3.3e-09 37.0 0.0 8.2 6 3 1 7 7 7 4 Fibronectin type III domain Neogenin_C PF06583.12 KER29175.1 - 5.4e-10 39.6 0.1 5.4e-10 39.6 0.1 3.0 3 0 0 3 3 3 1 Neogenin C-terminus Pur_ac_phosph_N PF16656.5 KER29175.1 - 2.4e-09 37.7 0.0 0.25 12.0 0.0 5.2 6 0 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain Serpin PF00079.20 KER29177.1 - 3.8e-48 164.7 0.0 4.5e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4750 PF15938.5 KER29178.1 - 0.21 11.2 2.0 0.32 10.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) APP_E2 PF12925.7 KER29179.1 - 6.7e-21 74.9 11.5 1.2e-20 74.0 11.5 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.16 KER29179.1 - 8.7e-11 42.1 0.1 2.9e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.9 KER29179.1 - 2.9e-05 24.4 0.0 0.0001 22.8 0.0 2.0 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus TUDOR_5 PF18359.1 KER29179.1 - 0.06 13.1 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Atypical_Card PF18461.1 KER29179.1 - 0.068 13.4 0.6 35 4.7 0.0 3.5 4 0 0 4 4 4 0 Atypical caspase recruitment domain ABC_tran_CTD PF16326.5 KER29179.1 - 0.17 12.2 2.8 0.22 11.8 0.6 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain GDP_Man_Dehyd PF16363.5 KER29182.1 - 3e-55 187.9 0.0 1.3e-54 185.9 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KER29182.1 - 5.2e-53 180.0 0.0 6.4e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KER29182.1 - 1.7e-10 40.5 0.0 2.9e-10 39.7 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KER29182.1 - 6.3e-10 38.7 0.0 1.8e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KER29182.1 - 2.8e-09 36.4 0.0 3.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KER29182.1 - 1.3e-06 27.7 0.0 2.2e-05 23.7 0.0 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KER29182.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KER29182.1 - 0.029 14.3 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 KER29182.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1815 PF08844.10 KER29182.1 - 0.049 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NAD_binding_10 PF13460.6 KER29182.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AMP-binding PF00501.28 KER29186.1 - 3.3e-65 220.3 0.9 3e-25 88.7 0.0 6.0 5 1 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.11 KER29186.1 - 3.4e-17 63.2 3.0 2e-14 54.4 0.0 2.7 3 0 0 3 3 3 2 DMAP1-binding Domain MTA_R1 PF17226.2 KER29186.1 - 0.00072 19.7 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 MTA R1 domain GvpG PF05120.12 KER29186.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G TCL1_MTCP1 PF01840.17 KER29186.1 - 0.074 12.7 0.1 23 4.7 0.0 2.9 3 0 0 3 3 3 0 TCL1/MTCP1 family BatA PF07584.11 KER29189.1 - 0.013 15.8 2.6 4.4 7.7 0.0 3.1 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal UPF1_Zn_bind PF09416.10 KER29190.1 - 1.5e-69 232.8 7.3 1.9e-69 232.5 3.9 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KER29190.1 - 1.5e-49 168.3 0.0 4.8e-49 166.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KER29190.1 - 1.3e-46 159.6 5.3 9.9e-28 97.6 0.9 2.6 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KER29190.1 - 3.7e-20 72.0 0.0 7.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KER29190.1 - 8.3e-13 48.5 0.2 5.7e-12 45.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KER29190.1 - 1.3e-10 41.7 0.1 3.3e-10 40.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KER29190.1 - 2e-07 31.2 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KER29190.1 - 1.6e-05 24.3 0.1 0.00053 19.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KER29190.1 - 0.00028 20.7 0.1 0.8 9.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KER29190.1 - 0.0019 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KER29190.1 - 0.0034 16.9 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KER29190.1 - 0.0091 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KER29190.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 KER29190.1 - 0.029 13.5 0.0 5.7 6.0 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 KER29190.1 - 0.032 14.5 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KER29190.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KER29190.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KER29190.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KER29190.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 KER29190.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ExbD PF02472.16 KER29191.1 - 0.36 11.0 4.4 2.1 8.5 4.4 2.1 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Endomucin PF07010.12 KER29191.1 - 2.2 8.2 27.3 3 7.8 27.3 1.2 1 0 0 1 1 1 0 Endomucin BAF1_ABF1 PF04684.13 KER29191.1 - 7 5.6 11.6 8.9 5.2 11.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GREB1 PF15782.5 KER29191.1 - 8.9 3.3 13.2 10 3.1 13.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_LBD PF02931.23 KER29192.1 - 6.7e-10 38.8 0.7 1.3e-09 37.9 0.7 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER29192.1 - 0.00058 20.0 3.8 0.00058 20.0 3.8 2.0 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region PGDYG PF14083.6 KER29198.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 PGDYG protein CUB PF00431.20 KER29201.1 - 4.8e-18 65.5 0.0 3.1e-11 43.6 0.0 2.5 3 0 0 3 3 3 2 CUB domain CUB PF00431.20 KER29202.1 - 2e-29 102.2 0.3 3.9e-15 56.1 0.1 2.2 2 0 0 2 2 2 2 CUB domain RVT_1 PF00078.27 KER29204.1 - 3.3e-14 52.9 0.0 9.6e-13 48.2 0.0 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RBD PF02196.15 KER29204.1 - 0.00021 21.3 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain CAP_N PF01213.19 KER29204.1 - 0.089 12.3 7.0 0.21 11.0 7.0 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BAMBI PF06211.12 KER29205.1 - 0.2 11.9 8.7 3.6 7.9 8.7 2.6 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Adenylsucc_synt PF00709.21 KER29206.1 - 6.3e-166 552.4 0.0 7.2e-166 552.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3668 PF12416.8 KER29207.1 - 1.5e-05 24.9 0.0 4.2e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Cep120 protein GldM_N PF12081.8 KER29207.1 - 0.002 18.3 7.0 0.0048 17.0 7.0 1.6 1 0 0 1 1 1 1 GldM N-terminal domain DUF4497 PF14924.6 KER29207.1 - 0.008 16.6 0.1 0.44 11.0 0.0 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4497) Bap31_Bap29_C PF18035.1 KER29207.1 - 0.41 10.7 6.4 6.7 6.8 1.3 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Occludin_ELL PF07303.13 KER29207.1 - 0.61 10.8 19.1 0.98 10.2 1.9 4.0 2 1 0 3 3 3 0 Occludin homology domain zf-C4H2 PF10146.9 KER29207.1 - 6.4 7.0 26.4 83 3.4 26.4 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein PACT_coil_coil PF10495.9 KER29208.1 - 9.2e-18 64.6 4.4 2.1e-17 63.5 0.0 3.9 3 0 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 KER29208.1 - 0.00028 20.9 17.5 0.00028 20.9 17.5 8.8 8 1 1 9 9 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sirohm_synth_C PF14823.6 KER29211.1 - 3.5 7.3 4.8 0.47 10.1 0.4 1.8 2 1 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal CaMBD PF02888.16 KER29212.1 - 6.3e-41 138.4 7.0 2.5e-21 75.6 1.2 2.6 2 0 0 2 2 2 2 Calmodulin binding domain Ion_trans_2 PF07885.16 KER29212.1 - 1.4e-06 28.2 1.4 2.1e-06 27.6 0.4 1.8 2 0 0 2 2 2 1 Ion channel MinC_N PF05209.13 KER29212.1 - 0.021 14.7 0.2 0.54 10.2 0.1 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain SK_channel PF03530.14 KER29213.1 - 3e-13 49.8 0.2 3.8e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 Calcium-activated SK potassium channel PTN_MK_N PF05196.13 KER29215.1 - 0.0016 18.6 0.6 1.7 9.0 0.1 2.2 2 0 0 2 2 2 2 PTN/MK heparin-binding protein family, N-terminal domain Adeno_Penton_B PF01686.17 KER29217.1 - 0.18 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein PPR_2 PF13041.6 KER29218.1 - 3.8e-17 62.2 0.0 1.6e-06 28.2 0.0 5.6 5 1 1 6 6 6 4 PPR repeat family LSM PF01423.22 KER29218.1 - 5.4e-15 54.8 0.3 1e-14 54.0 0.3 1.4 1 0 0 1 1 1 1 LSM domain PPR_3 PF13812.6 KER29218.1 - 3.5e-12 46.2 0.0 0.0002 21.4 0.0 4.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KER29218.1 - 8.4e-09 35.1 4.3 0.012 15.8 0.0 5.0 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 KER29218.1 - 3.9e-07 29.7 0.4 0.024 14.3 0.0 4.8 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 KER29218.1 - 0.00056 19.3 1.7 0.43 9.9 0.0 3.8 3 2 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 KER29218.1 - 0.0022 18.4 0.1 0.0099 16.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial transcriptional activator domain Arg_repressor PF01316.21 KER29218.1 - 0.11 12.2 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain Cadherin_pro PF08758.11 KER29218.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Cadherin prodomain like IQ PF00612.27 KER29219.1 - 1.7e-12 46.0 8.9 7e-05 22.3 0.4 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif RIIa PF02197.17 KER29219.1 - 5.8e-10 38.7 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF4862 PF16154.5 KER29219.1 - 0.016 14.5 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) Na_Ca_ex PF01699.24 KER29220.1 - 1.7e-23 83.2 13.2 1.9e-16 60.4 7.8 2.3 1 1 1 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 KER29221.1 - 7.4e-11 42.1 0.0 9.8e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 Calx-beta domain RPN6_N PF18055.1 KER29222.1 - 4.4e-33 114.1 0.0 8.9e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KER29222.1 - 1.7e-12 47.7 0.0 4.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KER29222.1 - 0.00068 19.6 0.4 1.7 8.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER29222.1 - 0.0023 18.6 0.7 0.0077 16.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER29222.1 - 0.0032 17.7 5.4 0.0053 17.0 2.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER29222.1 - 0.0061 16.0 0.8 0.0098 15.3 0.8 1.3 1 0 0 1 1 1 1 MalT-like TPR region RPN6_C_helix PF18503.1 KER29222.1 - 0.065 13.0 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain zf-H2C2_2 PF13465.6 KER29223.1 - 1e-16 60.5 12.3 3.6e-08 33.5 1.3 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KER29223.1 - 2.3e-12 46.6 17.3 1.8e-05 25.0 1.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER29223.1 - 3.2e-08 33.7 14.9 0.016 16.0 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER29223.1 - 0.0017 18.6 3.5 0.003 17.8 3.0 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KER29223.1 - 0.0025 18.0 7.2 1.3 9.4 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KER29223.1 - 0.051 13.2 1.0 0.62 9.7 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 KER29223.1 - 0.065 13.6 1.8 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-H2C2_5 PF13909.6 KER29223.1 - 0.067 13.0 0.0 0.067 13.0 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KER29223.1 - 0.17 11.8 8.2 1.1 9.2 0.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KER29223.1 - 0.24 11.5 10.0 3.5 7.7 1.5 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger Mcm10 PF09332.11 KER29223.1 - 0.3 10.5 4.0 0.49 9.8 4.0 1.3 1 0 0 1 1 1 0 Mcm10 replication factor zf-met PF12874.7 KER29223.1 - 2.1 8.9 5.4 7.4 7.1 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_Hakai PF18408.1 KER29223.1 - 3.7 7.3 6.5 8.9 6.1 0.6 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-C2HE PF16278.5 KER29223.1 - 7.8 7.0 11.8 1.9e+02 2.6 5.6 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C4 PF00105.18 KER29224.1 - 1.8e-18 66.8 17.0 2.4e-09 37.5 3.7 3.3 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER29224.1 - 6.2e-09 35.7 0.0 1.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SET PF00856.28 KER29227.1 - 5.7e-20 72.4 2.8 1.4e-19 71.1 0.3 3.1 2 0 0 2 2 2 1 SET domain FYRC PF05965.14 KER29227.1 - 9.7e-13 48.1 0.0 3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus PHD PF00628.29 KER29227.1 - 3.8e-08 33.1 59.8 3.1e-05 23.8 6.9 7.1 6 1 1 7 7 7 3 PHD-finger FYRN PF05964.14 KER29227.1 - 2.3e-05 24.1 0.5 0.00011 21.9 0.4 2.4 2 1 0 2 2 2 1 F/Y-rich N-terminus PBP1_TM PF14812.6 KER29227.1 - 0.73 10.2 3.1 3 8.3 3.1 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_9 PF14580.6 KER29229.1 - 5.2e-05 22.8 0.0 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat Pro-MCH PF05824.12 KER29229.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) Cation_efflux PF01545.21 KER29231.1 - 2.3e-44 151.5 7.1 2.3e-44 151.5 7.1 2.1 2 1 0 2 2 2 1 Cation efflux family Amidinotransf PF02274.17 KER29232.1 - 4.4e-05 22.7 0.0 0.27 10.3 0.0 2.6 3 0 0 3 3 3 2 Amidinotransferase GIY-YIG PF01541.24 KER29233.1 - 0.015 15.6 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Roc PF08477.13 KER29234.1 - 1.4e-05 25.3 0.8 0.0016 18.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 KER29234.1 - 6.2e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Death PF00531.22 KER29234.1 - 0.0037 17.4 0.1 0.014 15.5 0.1 2.1 1 0 0 1 1 1 1 Death domain Ras PF00071.22 KER29234.1 - 0.013 15.1 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Ras family DUF5333 PF17267.2 KER29234.1 - 0.077 13.2 0.1 0.36 11.0 0.1 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5333) Ank_2 PF12796.7 KER29235.1 - 6.2e-14 52.3 0.3 4.2e-12 46.5 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER29235.1 - 2.3e-11 43.6 0.2 9.8e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KER29235.1 - 2.8e-11 42.6 0.2 0.0027 18.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KER29235.1 - 3.1e-11 43.6 0.3 9.3e-05 22.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER29235.1 - 1.3e-10 41.3 2.7 5.3e-05 23.4 0.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER29236.1 - 3.1e-07 30.5 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER29236.1 - 0.00019 21.6 0.2 0.0017 18.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KER29236.1 - 0.00036 21.1 0.0 0.00068 20.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER29236.1 - 0.00076 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KER29236.1 - 0.11 13.0 0.5 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.16 KER29239.1 - 4.2e-43 147.6 40.3 3e-33 115.2 16.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KER29239.1 - 4.2e-05 22.6 8.3 4.2e-05 22.6 8.3 3.8 2 2 1 4 4 4 2 MFS_1 like family OATP PF03137.20 KER29239.1 - 0.00012 20.6 5.2 0.084 11.1 4.5 3.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ATG7_N PF16420.5 KER29239.1 - 0.23 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF2759 PF10958.8 KER29239.1 - 1.7 8.4 9.3 11 5.8 0.6 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Bravo_FIGEY PF13882.6 KER29241.1 - 1.9e-22 80.4 0.6 3.2e-22 79.7 0.6 1.4 1 0 0 1 1 1 1 Bravo-like intracellular region Cas1_AcylT PF07779.12 KER29243.1 - 1.6e-37 129.6 10.6 1.7e-36 126.2 10.6 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Cas1_AcylT PF07779.12 KER29244.1 - 3.1e-43 148.4 1.6 3.9e-43 148.1 1.6 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF2207 PF09972.9 KER29244.1 - 0.2 10.4 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TLD PF07534.16 KER29245.1 - 4.2e-16 59.4 0.1 4.1e-09 36.8 0.0 3.3 2 1 0 2 2 2 2 TLD LysM PF01476.20 KER29245.1 - 1.4e-10 41.1 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain Med19 PF10278.9 KER29245.1 - 5.6 6.9 11.8 12 5.8 11.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 zf-RING_14 PF17978.1 KER29246.1 - 0.21 12.0 0.0 0.31 11.5 0.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC_3 PF13917.6 KER29247.1 - 0.03 14.3 0.7 0.078 13.0 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle ParBc PF02195.18 KER29247.1 - 0.063 13.6 0.4 0.065 13.5 0.4 1.3 1 1 0 1 1 1 0 ParB-like nuclease domain BAR PF03114.18 KER29252.1 - 4.3e-29 101.8 2.3 6e-29 101.4 2.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KER29252.1 - 3.3e-14 52.5 0.1 5.8e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER29252.1 - 1.2e-13 50.5 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.9 KER29252.1 - 1.2e-11 44.3 0.8 1.7e-11 43.8 0.8 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_2 PF07653.17 KER29252.1 - 2.7e-11 42.9 0.0 5.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UPF0147 PF03685.13 KER29252.1 - 0.015 15.3 0.1 0.034 14.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) BAR PF03114.18 KER29253.1 - 7.2e-08 32.4 2.0 1e-07 31.8 2.0 1.2 1 0 0 1 1 1 1 BAR domain Spc7 PF08317.11 KER29253.1 - 0.094 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3419 PF11899.8 KER29255.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Nop14 PF04147.12 KER29256.1 - 0.11 10.7 36.7 0.12 10.6 36.7 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KER29256.1 - 0.37 8.8 50.0 0.48 8.5 50.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER29256.1 - 0.92 8.9 37.7 1.1 8.7 37.7 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 KER29256.1 - 0.95 8.8 27.4 1.1 8.6 27.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 KER29256.1 - 1 7.7 31.0 1.2 7.5 31.0 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop25 PF09805.9 KER29256.1 - 1.5 9.3 17.6 1.9 9.0 17.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NPR3 PF03666.13 KER29256.1 - 1.9 7.2 9.2 2 7.1 9.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5523 PF17661.1 KER29256.1 - 2.4 7.8 10.7 2.8 7.5 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RRN3 PF05327.11 KER29256.1 - 2.8 6.4 30.7 3 6.3 30.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SspB PF04386.13 KER29256.1 - 6.9 6.5 7.8 8.2 6.3 7.8 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Meis_PKNOX_N PF16493.5 KER29257.1 - 1.2e-23 83.2 0.6 1.2e-23 83.2 0.6 2.1 3 0 0 3 3 3 1 N-terminal of Homeobox Meis and PKNOX1 KNOX1 PF03790.13 KER29257.1 - 0.048 13.4 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 KNOX1 domain Homeobox_KN PF05920.11 KER29259.1 - 2.3e-15 56.2 1.8 7.5e-15 54.6 1.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KER29259.1 - 1.2e-06 28.3 0.3 3.1e-06 26.9 0.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KER29260.1 - 1.9e-07 30.8 0.5 3.8e-07 29.8 0.5 1.5 1 0 0 1 1 1 1 Homeodomain PNPase_C PF12111.8 KER29260.1 - 5 6.6 6.3 0.5 9.8 1.5 1.9 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Dynein_light PF01221.18 KER29263.1 - 2.5e-16 59.7 0.0 5e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Dynein light chain type 1 C2 PF00168.30 KER29264.1 - 1.1e-26 93.1 0.0 3.3e-14 53.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain PDZ_6 PF17820.1 KER29264.1 - 2.4e-10 40.1 0.1 4.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER29264.1 - 1.1e-09 38.5 0.2 2.1e-09 37.6 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER29264.1 - 0.0012 19.1 0.1 0.0027 18.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Arf PF00025.21 KER29267.1 - 3.6e-35 121.0 0.0 3.9e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KER29267.1 - 1e-05 25.7 0.1 1.3e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER29267.1 - 0.00073 19.2 0.0 0.00078 19.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KER29267.1 - 0.025 13.7 0.1 0.063 12.4 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit DAO PF01266.24 KER29269.1 - 4.2e-40 138.4 0.0 7.1e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KER29269.1 - 8.7e-40 135.5 0.0 1.9e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 KER29269.1 - 4.8e-12 46.2 0.4 9.9e-12 45.1 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KER29269.1 - 3.2e-07 30.1 0.2 9.1e-07 28.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair FAD_oxidored PF12831.7 KER29269.1 - 1.6e-06 27.8 0.2 2.4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KER29269.1 - 3.4e-06 26.4 0.6 3.3e-05 23.2 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain EF-hand_1 PF00036.32 KER29269.1 - 2.2e-05 23.7 0.1 0.0098 15.4 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER29269.1 - 0.00041 20.0 0.1 0.3 11.1 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 KER29269.1 - 0.00048 20.2 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand GIDA PF01134.22 KER29269.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KER29269.1 - 0.018 13.7 0.3 0.039 12.6 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KER29269.1 - 0.02 14.1 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KER29269.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF5580 PF17743.1 KER29269.1 - 0.057 12.0 0.1 0.078 11.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 KER29269.1 - 0.071 12.6 0.1 0.46 10.1 0.1 2.4 2 0 0 2 2 2 0 EF hand ARID PF01388.21 KER29271.1 - 2.7e-19 69.6 0.1 5.8e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DDE_Tnp_IS1595 PF12762.7 KER29275.1 - 3.8e-11 43.2 0.0 4.1e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain SMC_N PF02463.19 KER29277.1 - 1.5e-32 112.9 0.0 3.4e-32 111.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KER29277.1 - 1.8e-07 31.3 4.5 1.8e-07 31.3 4.5 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system GrpE PF01025.19 KER29277.1 - 0.008 15.9 0.8 0.008 15.9 0.8 4.5 3 2 1 4 4 2 1 GrpE SbcCD_C PF13558.6 KER29277.1 - 0.011 15.9 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sugarporin_N PF11471.8 KER29277.1 - 0.027 14.4 1.6 0.027 14.4 1.6 4.3 5 0 0 5 5 5 0 Maltoporin periplasmic N-terminal extension NRN1 PF15056.6 KER29277.1 - 0.053 13.6 2.9 0.5 10.5 1.0 3.0 3 0 0 3 3 3 0 Neuritin protein family AAA_13 PF13166.6 KER29277.1 - 0.18 10.4 24.5 0.86 8.2 14.4 2.6 1 1 0 2 2 2 0 AAA domain APG6_N PF17675.1 KER29277.1 - 1.6 9.3 50.0 0.47 11.0 22.2 4.2 3 1 1 4 4 4 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KER29277.1 - 2.8 8.5 10.3 4.3 7.9 0.1 4.3 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.20 KER29277.1 - 5.8 6.2 51.6 3.8 6.8 0.6 3.7 2 1 1 3 3 3 0 Tropomyosin DUF5344 PF17279.2 KER29277.1 - 9.9 6.8 14.0 1.1 9.9 0.7 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5344) Rogdi_lz PF10259.9 KER29278.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein CNPase PF05881.12 KER29280.1 - 9.6e-24 84.2 0.1 3.2e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_33 PF13671.6 KER29280.1 - 7e-10 39.2 0.0 1.8e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER29280.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 KER29280.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KER29280.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRRFIP PF09738.9 KER29282.1 - 2e-38 132.6 29.1 2e-38 132.6 29.1 3.3 1 1 1 2 2 2 2 LRRFIP family Macoilin PF09726.9 KER29282.1 - 0.00029 19.5 15.1 0.00029 19.5 15.1 2.8 1 1 1 2 2 2 1 Macoilin family Filament PF00038.21 KER29282.1 - 0.0017 18.0 35.9 0.058 13.0 5.0 4.1 2 1 2 4 4 4 3 Intermediate filament protein DUF1664 PF07889.12 KER29282.1 - 0.0019 18.2 18.2 1.3 9.1 0.9 3.9 2 1 1 3 3 3 3 Protein of unknown function (DUF1664) ATG16 PF08614.11 KER29282.1 - 0.012 15.8 21.7 0.012 15.8 21.7 3.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KER29282.1 - 0.017 15.6 46.7 0.071 13.6 25.3 4.0 2 2 1 3 3 3 0 Apg6 coiled-coil region DUF2935 PF11155.8 KER29282.1 - 0.21 11.9 3.1 1.4 9.3 1.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2353 PF09789.9 KER29282.1 - 0.23 10.8 31.1 0.026 13.9 18.5 2.4 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TMPIT PF07851.13 KER29282.1 - 0.23 10.7 20.1 0.92 8.7 9.9 2.7 2 1 1 3 3 3 0 TMPIT-like protein Leu_zip PF15294.6 KER29282.1 - 0.25 10.8 28.1 0.59 9.6 4.0 3.2 2 1 1 3 3 3 0 Leucine zipper Cnn_1N PF07989.11 KER29282.1 - 0.57 10.4 34.5 0.18 12.0 6.5 5.7 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 TolA_bind_tri PF16331.5 KER29282.1 - 0.58 10.3 35.5 0.31 11.2 8.8 4.5 2 2 1 3 3 3 0 TolA binding protein trimerisation EzrA PF06160.12 KER29282.1 - 0.86 7.7 25.1 0.94 7.6 12.7 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 KER29282.1 - 1.1 8.5 34.4 3 7.1 3.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 KER29282.1 - 1.2 9.2 46.1 1.3 9.1 18.7 4.5 3 1 1 4 4 3 0 TPR/MLP1/MLP2-like protein GOLGA2L5 PF15070.6 KER29282.1 - 4.6 5.8 32.4 0.29 9.7 11.8 3.0 2 1 1 3 3 3 0 Putative golgin subfamily A member 2-like protein 5 Atg14 PF10186.9 KER29282.1 - 5.4 6.0 33.9 0.62 9.1 3.7 3.3 2 1 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KER29282.1 - 5.8 6.2 28.5 0.79 9.0 16.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KER29282.1 - 8 6.5 35.6 0.049 13.7 9.4 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 KER29283.1 - 1.3e-29 103.3 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29283.1 - 1.4e-17 63.8 0.0 1.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER29283.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KER29283.1 - 0.25 10.6 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like UCH PF00443.29 KER29284.1 - 6.7e-68 229.0 0.0 8.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KER29284.1 - 1.4e-14 54.4 0.1 3.7e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KER29284.1 - 5.7e-12 45.9 0.1 1.6e-06 27.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 KER29284.1 - 0.061 13.2 2.0 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.7 KER29284.1 - 0.47 10.5 4.6 5.7 7.0 1.9 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PHD PF00628.29 KER29285.1 - 7.2e-14 51.4 26.6 2.6e-07 30.4 11.3 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 KER29285.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 KER29285.1 - 0.0035 16.9 0.5 0.0035 16.9 0.5 3.2 3 0 0 3 3 3 2 PHD-finger FHA PF00498.26 KER29285.1 - 0.0038 17.5 0.1 0.0097 16.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-HC5HC2H PF13771.6 KER29285.1 - 0.19 12.0 8.2 1 9.7 0.3 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KER29285.1 - 1.6 9.0 9.4 5.4 7.2 2.1 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain Cadherin PF00028.17 KER29287.1 - 1.7e-59 198.3 3.1 2e-15 57.0 0.0 9.6 8 2 0 8 8 8 6 Cadherin domain Cadherin_3 PF16184.5 KER29287.1 - 0.00023 21.1 7.9 0.06 13.4 0.3 5.6 6 1 0 6 6 6 1 Cadherin-like Cadherin_2 PF08266.12 KER29287.1 - 0.0035 17.1 0.0 0.1 12.5 0.0 3.3 3 0 0 3 3 3 1 Cadherin-like PyrBI_leader PF08052.11 KER29287.1 - 0.075 13.0 0.3 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 PyrBI operon leader peptide DUF5072 PF16807.5 KER29287.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) UQ_con PF00179.26 KER29288.1 - 4e-43 146.4 0.0 4.9e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER29288.1 - 2.2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 KER29288.1 - 0.00025 20.8 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RWD PF05773.22 KER29288.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF4539 PF15072.6 KER29289.1 - 1e-20 73.6 0.0 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Innexin PF00876.18 KER29292.1 - 6.7e-105 351.2 11.3 7.7e-105 351.0 11.3 1.0 1 0 0 1 1 1 1 Innexin zf-C2H2 PF00096.26 KER29293.1 - 7e-06 26.2 6.5 0.0003 21.1 4.0 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-3CxxC PF13695.6 KER29293.1 - 0.0063 17.0 1.8 0.012 16.0 1.8 1.5 1 0 0 1 1 1 1 Zinc-binding domain zf-C2H2_4 PF13894.6 KER29293.1 - 0.018 15.8 8.5 0.17 12.8 4.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KER29293.1 - 0.38 10.4 7.7 2.4 7.9 3.5 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KER29293.1 - 0.45 11.0 6.4 10 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf_UBZ PF18439.1 KER29293.1 - 1.8 8.2 7.4 7.9 6.2 4.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyco_transf_64 PF09258.10 KER29295.1 - 1.5e-05 24.4 0.0 1.7e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain SPOC PF07744.13 KER29300.1 - 6.7e-31 107.2 0.0 1.5e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 KER29300.1 - 3.6e-06 26.7 0.0 0.12 12.2 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.25 KER29301.1 - 1.9e-67 227.3 0.0 2.7e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER29301.1 - 1.9e-43 147.6 0.0 3.5e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER29301.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KER29301.1 - 0.029 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 KER29302.1 - 1e-57 195.5 0.0 1.4e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER29302.1 - 4.3e-49 165.9 0.0 6.7e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER29302.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MIP PF00230.20 KER29303.1 - 4.8e-43 147.5 17.4 3.4e-42 144.7 17.4 1.9 1 1 0 1 1 1 1 Major intrinsic protein Peptidase_M24 PF00557.24 KER29305.1 - 1.9e-43 148.6 0.1 2.6e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ntox34 PF15606.6 KER29305.1 - 0.1 12.7 0.8 0.65 10.2 0.3 2.5 3 0 0 3 3 3 0 Bacterial toxin 34 Peptidase_M16_M PF16187.5 KER29306.1 - 1.1e-77 261.1 0.0 2.9e-77 259.7 0.0 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KER29306.1 - 6e-38 130.2 0.0 1.7e-37 128.7 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KER29306.1 - 1.8e-29 103.0 0.1 8.3e-17 61.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Fibrillarin PF01269.17 KER29307.1 - 2e-99 331.3 0.0 3.2e-99 330.6 0.0 1.3 1 1 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KER29307.1 - 4.3e-05 23.3 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KER29307.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KER29307.1 - 0.065 13.4 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KER29307.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Rap_GAP PF02145.15 KER29308.1 - 3.7e-39 134.2 0.0 6.9e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP HEAT PF02985.22 KER29308.1 - 0.14 12.4 2.6 5.5 7.5 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat Ntox1 PF15500.6 KER29308.1 - 0.15 12.5 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 HEPN_STY4199 PF18729.1 KER29311.1 - 0.0031 16.8 0.6 0.0037 16.5 0.6 1.0 1 0 0 1 1 1 1 STY4199-like HEPN zf-C2H2_jaz PF12171.8 KER29312.1 - 5.2e-08 33.0 1.3 9.1e-08 32.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER29312.1 - 1.9e-07 31.2 1.2 3.1e-07 30.5 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KER29312.1 - 5.6e-05 22.8 1.7 0.00012 21.8 1.7 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2 PF00096.26 KER29312.1 - 0.15 12.5 0.8 0.38 11.3 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 KER29312.1 - 0.21 11.7 3.0 0.56 10.4 3.0 1.7 1 1 0 1 1 1 0 DBF zinc finger Tetraspanin PF00335.20 KER29313.1 - 2.1e-27 96.3 4.9 3e-27 95.8 4.9 1.2 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 KER29313.1 - 0.0086 16.2 5.2 0.018 15.2 5.2 1.5 1 0 0 1 1 1 1 CD20-like family DUF998 PF06197.13 KER29313.1 - 0.15 11.6 3.6 0.27 10.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1741 PF08427.10 KER29314.1 - 5e-61 206.3 1.1 1.1e-60 205.2 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Dymeclin PF09742.9 KER29314.1 - 0.00024 19.7 1.1 0.011 14.2 0.2 2.5 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein 7tm_1 PF00001.21 KER29316.1 - 4.3e-52 177.0 0.9 5.6e-52 176.7 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BRI3BP PF14965.6 KER29316.1 - 0.065 12.8 0.1 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF647 PF04884.14 KER29319.1 - 1.1e-75 254.4 6.9 3.7e-75 252.7 6.9 1.7 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Str_synth PF03088.16 KER29320.1 - 8.4e-18 64.3 0.0 9.4e-17 60.9 0.0 2.5 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 KER29320.1 - 1.5e-12 47.7 0.0 5.4e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KER29320.1 - 0.00025 21.2 0.0 0.0025 18.0 0.0 2.4 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 KER29320.1 - 0.0024 17.8 0.1 0.83 9.8 0.1 3.3 3 0 0 3 3 3 1 NHL repeat SGL PF08450.12 KER29321.1 - 3.1e-11 43.3 0.0 4.4e-10 39.6 0.0 2.2 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KER29321.1 - 3.8e-11 43.0 0.0 4.5e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KER29321.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Arylesterase DUF1325 PF07039.11 KER29322.1 - 2.9e-35 121.2 0.1 3.6e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KER29322.1 - 0.086 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 KER29322.1 - 0.11 12.3 0.9 15 5.5 0.2 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Voltage_CLC PF00654.20 KER29323.1 - 6e-97 325.1 27.5 1.4e-96 323.8 25.7 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KER29323.1 - 9.4e-12 45.2 0.4 1.2e-06 28.9 0.1 3.0 2 0 0 2 2 2 2 CBS domain zf-C3HC4_2 PF13923.6 KER29325.1 - 1.5e-09 37.5 7.5 2.3e-09 36.9 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 KER29325.1 - 4.6e-09 36.8 0.0 1.8e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4 PF00097.25 KER29325.1 - 2.3e-08 33.8 8.0 3.7e-08 33.1 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER29325.1 - 3.2e-05 23.8 5.8 6.6e-05 22.8 5.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KER29325.1 - 5.9e-05 23.3 6.9 9.6e-05 22.6 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER29325.1 - 0.00013 21.8 6.0 0.00019 21.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KER29325.1 - 0.00032 20.8 10.0 0.00057 20.0 10.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KER29325.1 - 0.00077 19.7 3.0 0.0014 18.9 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER29325.1 - 0.0023 17.9 5.6 0.0057 16.7 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 KER29325.1 - 0.007 16.2 2.4 0.015 15.1 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KER29325.1 - 0.2 11.5 4.7 0.38 10.7 4.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KER29325.1 - 2.2 8.2 7.1 5.9 6.8 7.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PP2C PF00481.21 KER29326.1 - 6.2e-71 239.0 0.0 6.3e-58 196.4 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KER29326.1 - 0.002 17.8 0.1 0.0081 15.8 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KER29326.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Fe-S_biosyn PF01521.20 KER29327.1 - 1e-12 48.3 0.0 3e-12 46.7 0.0 1.7 1 1 1 2 2 2 1 Iron-sulphur cluster biosynthesis Mcl1_mid PF12341.8 KER29328.1 - 2.5e-71 240.4 0.0 2.6e-70 237.1 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KER29328.1 - 1.8e-09 38.1 5.1 3.2e-06 27.8 0.0 5.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER29328.1 - 2.1e-05 24.7 0.0 0.38 11.1 0.0 5.0 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain HMG_box PF00505.19 KER29328.1 - 0.016 15.6 0.1 0.033 14.6 0.1 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Ge1_WD40 PF16529.5 KER29328.1 - 0.025 13.5 0.0 2.5 6.9 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ephrin PF00812.17 KER29331.1 - 2.3e-08 34.1 0.4 6.2e-08 32.7 0.4 1.8 1 0 0 1 1 1 1 Ephrin DUF2321 PF10083.9 KER29331.1 - 0.021 14.5 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) MCM PF00493.23 KER29333.1 - 1.6e-100 334.9 0.0 2.3e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KER29333.1 - 9.9e-38 128.8 0.8 2.4e-37 127.6 0.2 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KER29333.1 - 3.3e-29 101.1 0.2 2.3e-28 98.4 0.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KER29333.1 - 1.3e-19 70.7 2.8 3.2e-19 69.4 2.8 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 KER29333.1 - 1.3e-15 58.0 6.4 1.3e-15 58.0 6.4 2.3 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 KER29333.1 - 1.8e-10 40.6 0.0 1.5e-07 31.0 0.0 2.8 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KER29333.1 - 1.8e-07 31.1 0.0 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER29333.1 - 1.1e-06 28.6 0.0 3.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KER29333.1 - 0.0023 18.4 0.0 0.0092 16.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KER29333.1 - 0.011 15.5 0.1 0.98 9.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KER29333.1 - 0.27 11.6 3.5 9.2 6.6 0.1 3.6 3 1 0 3 3 3 0 AAA ATPase domain zf-H2C2_5 PF13909.6 KER29334.1 - 0.016 15.0 3.2 0.016 15.0 3.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KER29334.1 - 0.032 14.5 6.4 7.8 6.9 0.4 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KER29334.1 - 0.97 10.4 21.6 0.26 12.2 3.7 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger BAG PF02179.16 KER29335.1 - 0.041 14.3 0.2 0.57 10.7 0.1 2.2 1 1 1 2 2 2 0 BAG domain zf-C2H2_4 PF13894.6 KER29336.1 - 8e-24 82.3 51.8 0.0016 19.1 2.2 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KER29336.1 - 5.3e-23 80.1 55.3 7.9e-05 22.9 3.1 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER29336.1 - 2.3e-17 62.5 42.2 0.0033 17.8 1.7 8.2 8 1 0 8 8 7 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER29336.1 - 5e-15 55.3 27.7 0.056 13.7 0.6 7.5 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER29336.1 - 3.5e-12 46.0 38.6 0.014 15.4 1.5 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 KER29336.1 - 3.6e-11 43.1 35.7 0.016 15.5 0.6 7.9 8 0 0 8 8 7 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER29336.1 - 2.2e-08 34.2 35.2 6.8e-05 23.1 0.9 5.4 4 1 3 7 7 7 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 KER29336.1 - 3.8e-05 24.3 17.8 0.0071 17.0 0.1 4.4 2 2 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KER29336.1 - 0.00014 21.6 42.3 0.034 13.9 2.2 7.4 7 0 0 7 7 7 2 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 KER29336.1 - 0.0053 16.4 22.9 0.031 13.9 1.2 5.6 2 2 3 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 KER29336.1 - 0.0068 16.0 24.8 0.42 10.2 0.1 7.3 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KER29336.1 - 0.0082 16.2 24.4 0.0089 16.1 0.6 5.5 5 1 0 5 5 5 2 Zinc ribbon domain zf-C2H2_2 PF12756.7 KER29336.1 - 0.011 16.1 32.1 4.3 7.7 0.8 6.8 2 2 2 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 KER29336.1 - 0.033 14.1 1.5 0.033 14.1 1.5 4.1 5 0 0 5 5 4 0 Probable zinc-ribbon domain zf-C2H2_8 PF15909.5 KER29336.1 - 0.093 13.0 21.2 0.24 11.7 2.1 3.7 2 2 1 3 3 3 0 C2H2-type zinc ribbon Rad50_zn_hook PF04423.14 KER29336.1 - 0.095 12.6 3.8 9.5 6.1 0.1 3.3 2 1 1 3 3 3 0 Rad50 zinc hook motif Elf1 PF05129.13 KER29336.1 - 0.75 9.9 23.8 0.97 9.5 1.0 5.2 2 2 3 5 5 5 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 KER29336.1 - 1.1 8.7 15.5 30 4.2 0.1 5.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-MYST PF17772.1 KER29336.1 - 1.8 8.2 13.0 2 8.1 0.0 4.5 3 2 2 5 5 4 0 MYST family zinc finger domain DUF1610 PF07754.11 KER29336.1 - 2.3 8.3 14.0 1.8 8.6 0.3 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) zf_PR_Knuckle PF18445.1 KER29336.1 - 3.1 7.7 12.6 13 5.7 0.3 4.6 4 0 0 4 4 4 0 PR zinc knuckle motif zf-Sec23_Sec24 PF04810.15 KER29336.1 - 6 7.0 23.1 7.4 6.7 0.4 5.8 6 0 0 6 6 5 0 Sec23/Sec24 zinc finger SHMT PF00464.19 KER29337.1 - 5.1e-158 525.9 0.0 6.3e-95 318.1 0.0 2.0 2 0 0 2 2 2 2 Serine hydroxymethyltransferase Nuc_deoxyri_tr2 PF15891.5 KER29339.1 - 1.9e-21 76.4 0.3 1.6e-15 57.4 0.2 2.5 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like RasGAP PF00616.19 KER29341.1 - 7.7e-30 104.2 0.4 3.5e-28 98.7 0.4 2.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Raf1_N PF18578.1 KER29341.1 - 0.012 16.0 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain FlgN PF05130.12 KER29341.1 - 0.062 13.8 3.3 0.17 12.4 0.1 2.8 3 0 0 3 3 3 0 FlgN protein DUF948 PF06103.11 KER29341.1 - 0.31 11.3 2.2 1.7 9.0 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sulfatase_C PF14707.6 KER29341.1 - 0.39 11.5 1.8 1.7 9.4 0.1 2.8 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase DUF3322 PF11795.8 KER29341.1 - 0.48 10.4 5.3 0.34 10.9 0.4 3.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) ATG16 PF08614.11 KER29341.1 - 0.52 10.5 6.4 0.45 10.7 2.2 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KER29341.1 - 6.4 7.2 8.2 0.49 10.8 2.0 2.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) RVT_1 PF00078.27 KER29342.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RasGEF PF00617.19 KER29345.1 - 4.3e-26 92.2 0.1 1.2e-25 90.8 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KER29345.1 - 1.2e-10 41.5 0.1 3e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SHMT PF00464.19 KER29348.1 - 6.7e-145 482.7 0.0 8.2e-145 482.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Insulin_TMD PF17870.1 KER29349.1 - 0.0044 17.0 1.3 0.0072 16.4 1.3 1.3 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment TMEM154 PF15102.6 KER29349.1 - 0.011 15.7 0.2 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.7 KER29349.1 - 0.035 13.6 0.3 0.05 13.1 0.3 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SUa-2TM PF18179.1 KER29349.1 - 0.036 13.4 1.2 0.15 11.4 0.3 1.9 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain FeoB_associated PF12669.7 KER29349.1 - 0.059 13.8 1.9 0.059 13.8 1.9 1.7 1 1 1 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2207 PF09972.9 KER29349.1 - 0.07 11.9 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 KER29349.1 - 0.59 10.5 3.2 0.33 11.3 1.1 1.6 2 0 0 2 2 2 0 Orf78 (ac78) Ras PF00071.22 KER29352.1 - 2.9e-15 56.2 0.0 3.2e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Phytochelatin PF05023.14 KER29353.1 - 3e-81 271.7 0.0 4.2e-81 271.2 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 KER29353.1 - 0.029 14.9 0.1 12 6.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_C39 PF03412.15 KER29353.1 - 0.13 12.0 0.0 10 5.9 0.0 3.1 4 0 0 4 4 4 0 Peptidase C39 family Collagen PF01391.18 KER29354.1 - 6.7e-05 22.6 8.8 0.00011 21.9 8.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) C1q PF00386.21 KER29355.1 - 4.6e-09 36.5 0.0 6.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 C1q domain Exo_endo_phos PF03372.23 KER29356.1 - 6.5e-14 52.0 0.0 1.7e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Calcipressin PF04847.12 KER29357.1 - 1.1e-22 80.8 3.0 2.3e-16 60.1 4.6 2.8 2 1 0 2 2 2 2 Calcipressin LRR_4 PF12799.7 KER29359.1 - 5.2e-05 23.5 0.2 0.00079 19.8 0.2 2.8 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER29359.1 - 0.00035 20.1 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KER29359.1 - 0.00055 19.6 0.2 0.0051 16.5 0.0 2.6 2 1 1 3 3 3 1 Leucine rich repeat SART-1 PF03343.13 KER29359.1 - 0.0058 15.2 2.0 0.0095 14.5 0.1 2.0 2 1 0 2 2 2 1 SART-1 family LRR_6 PF13516.6 KER29359.1 - 0.028 14.4 2.3 0.21 11.7 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 KER29359.1 - 0.063 13.8 0.1 3.4 8.6 0.0 3.2 2 1 0 2 2 2 0 Leucine Rich Repeat Vps26 PF03643.15 KER29360.1 - 4.8e-67 225.9 0.0 7.4e-38 130.1 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Yippee-Mis18 PF03226.14 KER29362.1 - 3.5e-13 49.7 0.7 5.2e-13 49.1 0.7 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 KER29362.1 - 0.082 13.1 0.2 0.082 13.1 0.2 1.7 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Haemadin PF09065.10 KER29363.1 - 0.02 14.6 0.8 0.031 14.1 0.8 1.2 1 0 0 1 1 1 0 Haemadin GpcrRhopsn4 PF10192.9 KER29365.1 - 8e-28 97.5 17.2 1.6e-14 53.9 5.6 2.5 2 1 0 2 2 2 2 Rhodopsin-like GPCR transmembrane domain Pkinase PF00069.25 KER29367.1 - 8.3e-63 212.2 0.0 9.9e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29367.1 - 1.6e-26 93.2 0.0 2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER29367.1 - 1.1e-05 24.9 0.1 1.7e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER29367.1 - 0.056 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3256 PF11644.8 KER29367.1 - 0.078 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) RIO1 PF01163.22 KER29367.1 - 0.084 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 RIO1 family SET PF00856.28 KER29368.1 - 5.1e-09 36.7 0.0 2.6e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 SET domain PHD PF00628.29 KER29368.1 - 4.5e-07 29.6 11.4 1.2e-06 28.3 11.4 1.8 1 0 0 1 1 1 1 PHD-finger Glycos_transf_1 PF00534.20 KER29370.1 - 3e-18 65.9 0.0 8.9e-18 64.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KER29370.1 - 2.8e-07 30.8 0.0 5.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KER29370.1 - 7.8e-07 29.6 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 UQ_con PF00179.26 KER29371.1 - 1.3e-11 44.3 0.1 6.4e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RVT_1 PF00078.27 KER29374.1 - 0.0042 16.6 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SMAP PF15477.6 KER29375.1 - 6.3e-13 49.5 0.5 6.3e-13 49.5 0.5 2.5 2 1 0 2 2 2 1 Small acidic protein family Retinal PF15449.6 KER29375.1 - 7.3 4.2 34.5 9.6 3.8 34.5 1.1 1 0 0 1 1 1 0 Retinal protein Ribosomal_S9 PF00380.19 KER29378.1 - 8.1e-24 84.5 0.0 1.1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 GLE1 PF07817.13 KER29380.1 - 7e-42 143.4 0.0 7.3e-41 140.0 0.0 2.2 1 1 0 1 1 1 1 GLE1-like protein Sugar_tr PF00083.24 KER29382.1 - 8.4e-92 308.4 35.5 2.2e-31 109.2 0.1 4.1 4 0 0 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 KER29382.1 - 1.3e-19 70.3 28.5 1.8e-15 56.8 19.8 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily PSI_integrin PF17205.3 KER29382.1 - 6.3 6.6 11.9 0.15 11.9 5.0 1.9 2 0 0 2 2 2 0 Integrin plexin domain ABC_membrane PF00664.23 KER29383.1 - 3.3e-91 305.7 42.1 4.1e-46 157.8 14.5 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KER29383.1 - 6.7e-70 233.9 0.1 9.3e-37 126.6 0.4 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KER29383.1 - 2e-13 50.3 1.4 2.3e-05 23.9 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KER29383.1 - 4.5e-11 42.2 0.3 4.9e-05 22.3 0.1 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KER29383.1 - 1.5e-09 38.0 0.0 0.0004 20.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KER29383.1 - 4.4e-09 37.0 1.0 0.0013 19.1 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KER29383.1 - 1.2e-08 35.2 0.0 0.56 9.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KER29383.1 - 2.4e-08 33.6 0.1 0.0048 16.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KER29383.1 - 3.4e-07 30.6 0.9 0.044 14.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 KER29383.1 - 1.8e-06 27.4 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 KER29383.1 - 4e-06 27.4 0.0 0.0037 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KER29383.1 - 7.6e-06 25.9 0.0 0.083 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KER29383.1 - 2.6e-05 23.6 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 KER29383.1 - 9.8e-05 22.3 0.4 0.083 12.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 KER29383.1 - 9.9e-05 21.9 0.0 0.42 10.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 KER29383.1 - 0.00039 20.2 0.2 0.88 9.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.20 KER29383.1 - 0.00046 20.1 0.0 0.043 13.7 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase NB-ARC PF00931.22 KER29383.1 - 0.00047 19.4 0.0 0.9 8.7 0.0 2.6 2 1 0 2 2 2 2 NB-ARC domain AAA_5 PF07728.14 KER29383.1 - 0.00049 20.1 0.0 2.4 8.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KER29383.1 - 0.00057 19.9 0.0 0.67 10.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KER29383.1 - 0.00088 19.6 0.0 0.82 9.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain PRK PF00485.18 KER29383.1 - 0.001 18.8 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 KER29383.1 - 0.0014 18.2 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KER29383.1 - 0.0016 17.7 0.0 0.28 10.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KER29383.1 - 0.0025 18.2 0.0 3.1 8.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase CPT PF07931.12 KER29383.1 - 0.0026 17.6 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.25 KER29383.1 - 0.0026 17.4 0.2 0.88 9.2 0.0 3.1 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KER29383.1 - 0.0027 18.1 0.1 29 5.1 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KER29383.1 - 0.0044 17.2 4.1 2.5 8.4 0.5 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KER29383.1 - 0.0056 17.2 5.8 0.39 11.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KER29383.1 - 0.0078 16.0 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KER29383.1 - 0.0081 15.4 0.0 3.1 6.9 0.0 2.7 3 0 0 3 3 2 1 KAP family P-loop domain TsaE PF02367.17 KER29383.1 - 0.012 15.6 0.0 7.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KER29383.1 - 0.015 15.4 0.0 0.79 9.8 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 KER29383.1 - 0.019 14.6 0.0 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad17 PF03215.15 KER29383.1 - 0.021 14.8 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain KdpD PF02702.17 KER29383.1 - 0.031 13.8 0.1 25 4.3 0.0 3.2 2 1 1 3 3 3 0 Osmosensitive K+ channel His kinase sensor domain AAA_14 PF13173.6 KER29383.1 - 0.035 14.1 0.0 11 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 KER29383.1 - 0.039 13.5 0.1 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KER29383.1 - 0.043 13.1 0.0 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Septin MeaB PF03308.16 KER29383.1 - 0.048 12.6 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KER29383.1 - 0.049 13.5 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 KER29383.1 - 0.063 13.0 0.0 23 4.6 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KER29383.1 - 0.064 12.3 0.1 0.51 9.3 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein Roc PF08477.13 KER29383.1 - 0.064 13.5 0.0 9.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KER29383.1 - 0.066 13.4 1.0 4.4 7.5 0.4 3.0 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KER29383.1 - 0.072 12.8 0.3 15 5.3 0.1 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 KER29383.1 - 0.078 11.8 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) dNK PF01712.19 KER29383.1 - 0.11 12.4 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF3148 PF11347.8 KER29383.1 - 0.14 11.9 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) MscS_TM PF12794.7 KER29384.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SH3_9 PF14604.6 KER29385.1 - 6.7e-13 48.3 0.1 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER29385.1 - 2.9e-10 39.6 1.6 3.7e-10 39.3 0.2 1.9 2 0 0 2 2 2 1 SH3 domain Cofilin_ADF PF00241.20 KER29385.1 - 4e-10 39.5 0.0 6.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KER29385.1 - 4.3e-10 39.1 0.0 8.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RsfS PF02410.15 KER29388.1 - 3.1e-14 53.2 0.0 4.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PDCD2_C PF04194.13 KER29392.1 - 2.6e-18 66.7 2.9 1.2e-17 64.5 0.3 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain BAR PF03114.18 KER29393.1 - 4.1e-56 190.3 11.2 1.5e-54 185.2 11.2 2.0 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KER29393.1 - 5.4e-16 58.2 0.2 1.1e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER29393.1 - 2.7e-14 52.5 0.1 4.7e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KER29393.1 - 3.5e-12 45.8 0.1 6.4e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 KER29393.1 - 9.9e-10 38.0 7.3 3.2e-06 26.5 3.6 2.3 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD_oxidored PF12831.7 KER29393.1 - 0.063 12.6 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase MHC_II_beta PF00969.19 KER29393.1 - 0.066 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain IBN_N PF03810.19 KER29396.1 - 2.6e-15 56.1 1.0 1.5e-10 40.8 0.0 4.4 4 0 0 4 4 4 2 Importin-beta N-terminal domain HEAT PF02985.22 KER29396.1 - 0.0025 17.9 1.6 1.9 8.9 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat Cse1 PF08506.10 KER29396.1 - 0.0053 15.6 0.2 0.051 12.4 0.0 2.6 3 0 0 3 3 3 1 Cse1 RTP1_C1 PF10363.9 KER29396.1 - 0.0081 16.3 3.4 0.065 13.4 0.1 3.9 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KER29396.1 - 0.017 14.7 0.3 0.93 9.0 0.4 2.6 2 0 0 2 2 2 0 CLASP N terminal Cnd1 PF12717.7 KER29396.1 - 0.028 14.5 0.6 0.48 10.5 0.1 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 KER29396.1 - 0.031 14.6 0.3 2.6 8.5 0.0 3.9 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain NUC130_3NT PF08158.12 KER29396.1 - 0.11 12.8 1.8 5.8 7.3 0.9 3.0 2 0 0 2 2 2 0 NUC130/3NT domain HEAT_EZ PF13513.6 KER29396.1 - 0.15 12.6 8.9 0.15 12.6 0.4 4.4 2 1 1 3 3 3 0 HEAT-like repeat Cwf_Cwc_15 PF04889.12 KER29396.1 - 2.5 7.8 13.8 4.4 7.0 13.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 KER29396.1 - 2.9 8.6 14.3 6.2 7.5 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) V-ATPase_H_N PF03224.14 KER29396.1 - 4.3 6.5 7.3 16 4.7 0.1 3.8 4 2 0 4 4 4 0 V-ATPase subunit H SDA1 PF05285.12 KER29396.1 - 4.4 6.6 11.8 6.8 6.0 11.8 1.2 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KER29396.1 - 4.5 6.4 6.8 8.5 5.5 6.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KER29396.1 - 7.1 4.7 14.5 4.9 5.2 12.1 1.8 2 0 0 2 2 2 0 Nop14-like family zf-C2H2 PF00096.26 KER29397.1 - 6e-09 35.9 23.6 0.0086 16.5 3.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER29397.1 - 1.2e-08 34.9 17.6 2.2e-06 27.9 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain GAGA PF09237.11 KER29397.1 - 0.00016 21.4 0.3 0.0079 16.0 0.1 2.7 2 0 0 2 2 2 1 GAGA factor zf-C2H2_4 PF13894.6 KER29397.1 - 0.00023 21.8 22.5 0.092 13.6 3.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KER29397.1 - 0.0003 21.1 15.0 0.16 12.4 0.4 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KER29397.1 - 0.00041 20.6 8.0 0.0023 18.2 3.8 3.0 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KER29397.1 - 0.0042 16.8 4.3 0.0042 16.8 4.3 3.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain Vps36-NZF-N PF16988.5 KER29397.1 - 0.094 12.1 1.1 1.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Endonuclease_7 PF02945.15 KER29397.1 - 0.16 11.9 2.3 0.47 10.4 2.3 1.9 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_2 PF12756.7 KER29397.1 - 0.22 11.9 9.3 21 5.5 0.4 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KER29397.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.6 2 1 1 3 3 3 0 BED zinc finger C1_1 PF00130.22 KER29397.1 - 0.74 9.8 5.3 4.7 7.2 2.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrsD PF12013.8 KER29397.1 - 2.4 8.6 14.0 2.1 8.8 0.4 3.9 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D MMR_HSR1 PF01926.23 KER29398.1 - 5.2e-14 52.3 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 KER29398.1 - 8.7e-06 26.3 9.3 2.6e-05 24.7 9.3 1.8 1 1 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 KER29398.1 - 0.0007 20.2 0.0 0.0056 17.3 0.0 2.4 1 1 0 1 1 1 1 GTP-binding GTPase N-terminal RVT_1 PF00078.27 KER29398.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_16 PF13191.6 KER29398.1 - 0.067 13.6 0.3 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MutL_C PF08676.11 KER29399.1 - 5.3e-07 29.5 0.0 0.00015 21.6 0.0 2.7 2 1 0 2 2 2 2 MutL C terminal dimerisation domain TEX19 PF15553.6 KER29400.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 DNA_pol_A_exo1 PF01612.20 KER29401.1 - 7.3e-40 136.5 0.8 1.5e-39 135.5 0.8 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KER29401.1 - 2.3e-14 53.1 0.0 5.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 KER29401.1 - 1.3e-12 48.2 0.1 3.6e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Glyco_transf_8 PF01501.20 KER29402.1 - 2e-23 83.3 0.1 8.1e-22 78.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KER29402.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_hydro_35 PF01301.19 KER29403.1 - 1.1e-55 189.5 0.0 2.2e-55 188.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KER29403.1 - 0.48 11.0 5.0 4.9 7.8 0.1 3.3 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain Integrin_alpha2 PF08441.12 KER29405.1 - 0.073 11.9 0.0 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 Integrin alpha Integrin_alpha PF00357.20 KER29405.1 - 0.11 12.5 0.8 0.31 11.1 0.8 1.8 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Adeno_E3_CR2 PF02439.15 KER29405.1 - 0.15 11.8 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Collectrin PF16959.5 KER29405.1 - 0.26 11.1 0.7 0.49 10.2 0.7 1.4 1 0 0 1 1 1 0 Renal amino acid transporter Cupin_8 PF13621.6 KER29408.1 - 3.3e-30 105.6 0.4 1.1e-29 104.0 0.4 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KER29408.1 - 2.4e-09 37.1 0.0 8.4e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KER29408.1 - 2.2e-06 28.1 0.1 4.7e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase OTU PF02338.19 KER29408.1 - 4.7e-05 23.9 0.0 9.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Cupin_2 PF07883.11 KER29408.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_6 PF12852.7 KER29408.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cupin Cupin_1 PF00190.22 KER29408.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Myosin_head PF00063.21 KER29409.1 - 1.8e-83 280.9 0.0 2.5e-35 121.9 0.0 4.9 4 1 0 4 4 4 4 Myosin head (motor domain) AAA_16 PF13191.6 KER29409.1 - 0.0039 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KER29409.1 - 0.0069 16.7 0.0 0.42 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KER29409.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KER29409.1 - 0.061 13.1 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KER29409.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KER29409.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DDHD PF02862.17 KER29411.1 - 3.2e-37 128.9 0.7 9.9e-29 101.1 0.0 2.5 1 1 1 2 2 2 2 DDHD domain YlbD_coat PF14071.6 KER29411.1 - 1.4 9.2 4.7 22 5.3 0.2 2.7 2 0 0 2 2 2 0 Putative coat protein zf-CCCH PF00642.24 KER29412.1 - 4.7e-07 29.5 29.1 2.3e-06 27.3 1.9 4.8 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER29412.1 - 0.00017 21.5 20.2 0.00024 21.1 2.0 4.2 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 KER29412.1 - 0.00041 20.1 20.9 0.00055 19.7 0.9 4.0 4 0 0 4 4 4 2 CCCH-type zinc finger Torus PF16131.5 KER29412.1 - 0.33 11.6 14.8 0.6 10.8 1.4 3.3 1 1 2 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 KER29412.1 - 1.4 9.1 11.0 0.3 11.3 4.6 2.5 1 1 1 2 2 2 0 Zinc-finger containing family Syntaxin-6_N PF09177.11 KER29413.1 - 6.9e-26 90.7 3.2 1.4e-25 89.7 0.6 2.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.19 KER29413.1 - 7.9e-06 25.8 0.5 4.8e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 SNARE domain NleF_casp_inhib PF16809.5 KER29413.1 - 0.012 15.5 1.8 0.014 15.3 0.2 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor EzrA PF06160.12 KER29413.1 - 0.014 13.6 1.5 0.93 7.6 0.1 2.4 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA AbiJ_NTD5 PF18865.1 KER29413.1 - 0.035 13.9 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Noelin-1 PF12308.8 KER29413.1 - 0.04 13.9 2.8 7.7 6.6 0.0 3.2 2 1 1 3 3 3 0 Neurogenesis glycoprotein Hpt PF01627.23 KER29413.1 - 0.042 14.1 2.9 0.79 10.0 0.4 2.9 3 0 0 3 3 3 0 Hpt domain Syntaxin_2 PF14523.6 KER29413.1 - 0.062 13.7 3.5 5.4 7.5 0.1 2.5 2 1 0 2 2 2 0 Syntaxin-like protein ATG16 PF08614.11 KER29413.1 - 0.071 13.3 0.5 0.071 13.3 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 KER29413.1 - 0.073 13.3 2.0 18 5.6 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 KER29413.1 - 0.089 11.7 3.2 4.7 6.1 0.1 2.5 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 KER29413.1 - 0.17 11.9 1.6 13 5.8 0.0 2.7 2 1 0 2 2 2 0 Laminin Domain II Spectrin PF00435.21 KER29413.1 - 0.23 12.0 5.1 2.4 8.7 0.9 2.5 2 0 0 2 2 2 0 Spectrin repeat DUF16 PF01519.16 KER29413.1 - 0.24 11.9 1.3 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 RXLR PF16810.5 KER29413.1 - 0.41 11.1 2.1 18 5.7 0.5 2.6 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DHR10 PF18595.1 KER29413.1 - 0.88 9.6 5.7 1.3 9.1 0.5 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KER29413.1 - 0.93 10.0 5.0 9.7 6.7 0.2 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CorA PF01544.18 KER29413.1 - 3 7.1 10.3 0.066 12.5 0.5 2.5 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein LRR_8 PF13855.6 KER29414.1 - 3.3e-14 52.4 2.0 5.8e-13 48.4 0.7 2.9 1 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KER29414.1 - 0.0026 18.1 3.0 0.29 11.6 0.0 3.7 2 2 1 4 4 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER29414.1 - 0.03 14.8 6.7 0.37 11.5 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat ig PF00047.25 KER29414.1 - 0.034 14.3 0.4 0.15 12.3 0.2 2.2 2 1 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.6 KER29414.1 - 0.049 14.2 0.1 0.2 12.3 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain LRR_6 PF13516.6 KER29414.1 - 0.24 11.6 3.4 8.5 6.7 0.0 4.1 4 1 1 5 5 5 0 Leucine Rich repeat DUF3246 PF11596.8 KER29415.1 - 0.036 13.5 3.2 0.038 13.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FA_desaturase PF00487.24 KER29415.1 - 0.37 10.6 2.3 0.54 10.0 2.3 1.3 1 0 0 1 1 1 0 Fatty acid desaturase MFAP1 PF06991.11 KER29415.1 - 6.3 6.6 7.6 6.9 6.5 7.6 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Ion_trans PF00520.31 KER29416.1 - 4.6e-17 62.1 8.3 5.9e-17 61.7 8.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KER29417.1 - 4.8e-24 84.9 28.4 1.4e-14 54.0 6.1 2.1 2 0 0 2 2 2 2 Ion transport protein DUF2516 PF10724.9 KER29417.1 - 0.58 10.5 10.9 3 8.2 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) cNMP_binding PF00027.29 KER29418.1 - 3.6e-18 65.4 0.0 6.3e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-RING_5 PF14634.6 KER29419.1 - 0.00029 20.7 9.1 0.00072 19.5 9.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain PRKG1_interact PF15898.5 KER29419.1 - 0.0062 17.4 6.8 0.13 13.1 2.8 2.4 1 1 1 2 2 2 2 cGMP-dependent protein kinase interacting domain CCCAP PF15964.5 KER29419.1 - 0.007 14.7 4.0 0.0093 14.3 4.0 1.1 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family DMPK_coil PF08826.10 KER29419.1 - 0.0074 16.4 3.0 0.019 15.1 3.0 1.7 1 0 0 1 1 1 1 DMPK coiled coil domain like DUF1664 PF07889.12 KER29419.1 - 0.043 13.9 1.4 0.081 13.0 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prok-RING_4 PF14447.6 KER29419.1 - 0.085 12.7 6.9 0.27 11.1 6.5 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HALZ PF02183.18 KER29419.1 - 0.17 12.2 2.9 0.32 11.3 2.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-MIZ PF02891.20 KER29419.1 - 0.8 9.5 6.8 2.2 8.1 6.8 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KER29419.1 - 7.6 6.5 10.5 8.6 6.3 7.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATG7_N PF16420.5 KER29420.1 - 1.1e-71 241.9 0.0 1.1e-71 241.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KER29420.1 - 1e-40 139.6 0.0 2.2e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family zf-CCHC_3 PF13917.6 KER29420.1 - 2.3e-11 43.4 5.0 4.8e-11 42.4 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Shikimate_DH PF01488.20 KER29420.1 - 0.069 13.2 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cwf_Cwc_15 PF04889.12 KER29420.1 - 0.35 10.6 11.7 0.57 9.9 11.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Polyoma_coat2 PF00761.20 KER29420.1 - 0.58 9.8 1.7 0.93 9.1 1.7 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein NPR3 PF03666.13 KER29420.1 - 7 5.3 13.8 11 4.7 13.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 KER29420.1 - 8.9 4.7 16.1 13 4.2 16.1 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M8 PF01457.16 KER29424.1 - 1.5e-13 50.3 4.0 1.1e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 Leishmanolysin RecR PF02132.15 KER29424.1 - 0.27 10.8 6.7 1.8 8.2 3.0 2.9 2 0 0 2 2 2 0 RecR protein UPF0489 PF12640.7 KER29425.1 - 3.7e-07 30.5 0.8 3.7e-06 27.3 0.5 2.6 2 1 0 2 2 2 1 UPF0489 domain SH3_15 PF18346.1 KER29426.1 - 0.078 13.3 0.3 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain AIP3 PF03915.13 KER29429.1 - 3.7e-11 42.8 7.5 5.1e-10 39.0 7.5 2.5 1 1 0 1 1 1 1 Actin interacting protein 3 RVT_1 PF00078.27 KER29429.1 - 1.6e-08 34.3 0.0 9.1e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SUIM_assoc PF16619.5 KER29429.1 - 9.1e-05 22.4 0.6 0.0005 20.1 0.6 2.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Syntaxin-6_N PF09177.11 KER29429.1 - 0.0082 16.7 0.7 0.073 13.6 0.2 2.6 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4600 PF15372.6 KER29429.1 - 6.6 7.2 8.0 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Ig_3 PF13927.6 KER29430.1 - 0.00036 21.1 0.4 0.0022 18.5 0.4 2.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER29430.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER29430.1 - 0.0013 19.0 0.7 0.033 14.5 0.1 3.0 2 0 0 2 2 2 1 Immunoglobulin domain Cas_Cmr3 PF09700.10 KER29430.1 - 0.0021 17.5 2.4 1.1 8.7 0.2 2.2 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cmr3) GAD-like PF08887.11 KER29430.1 - 0.0023 17.7 0.4 3.2 7.6 0.1 2.6 2 0 0 2 2 2 2 GAD-like domain V-set PF07686.17 KER29430.1 - 0.0025 18.0 1.1 0.28 11.4 0.7 3.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain SUB1_ProdP9 PF18213.1 KER29430.1 - 0.043 13.6 0.0 15 5.5 0.0 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 ig PF00047.25 KER29430.1 - 0.63 10.3 3.1 0.98 9.6 0.7 2.6 2 1 0 2 2 2 0 Immunoglobulin domain DOCK-C2 PF14429.6 KER29432.1 - 1e-24 87.5 0.1 1.9e-23 83.3 0.1 2.4 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KER29432.1 - 4.1e-21 75.2 0.0 1.2e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 KER29432.1 - 1e-06 27.9 4.2 0.0027 16.7 0.1 3.3 3 0 0 3 3 3 2 DOCK N-terminus Peptidase_M17 PF00883.21 KER29434.1 - 6.1e-58 196.5 0.2 7.8e-58 196.2 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RNase_PH PF01138.21 KER29435.1 - 1.6e-20 73.9 0.0 3.3e-10 40.6 0.0 2.3 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 TcfC PF16967.5 KER29435.1 - 0.015 14.8 0.0 3.3 7.3 0.0 3.0 3 0 0 3 3 3 0 E-set like domain Sterol-sensing PF12349.8 KER29436.1 - 1.5e-42 145.1 9.8 2.7e-42 144.2 9.8 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KER29436.1 - 3.4e-15 55.2 11.6 5.4e-15 54.6 11.6 1.2 1 0 0 1 1 1 1 Patched family PIG-P PF08510.12 KER29436.1 - 0.059 13.3 3.2 0.19 11.6 0.0 3.0 2 0 0 2 2 2 0 PIG-P WD40 PF00400.32 KER29436.1 - 0.15 12.9 4.5 12 7.0 0.1 4.2 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3089 PF11288.8 KER29436.1 - 0.17 11.4 0.3 23 4.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) DUF2151 PF10221.9 KER29439.1 - 1.5e-78 265.1 0.6 5.5e-51 174.0 0.0 2.0 2 0 0 2 2 2 2 Cell cycle and development regulator F-actin_cap_A PF01267.17 KER29440.1 - 1.3e-79 267.4 0.0 1.6e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit RhoGEF PF00621.20 KER29441.1 - 4.9e-35 121.4 3.7 9e-35 120.6 3.7 1.5 1 0 0 1 1 1 1 RhoGEF domain Phytase-like PF13449.6 KER29441.1 - 0.051 13.5 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Esterase-like activity of phytase PHD PF00628.29 KER29443.1 - 1.9e-15 56.5 24.0 1.6e-08 34.3 6.7 2.8 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 KER29443.1 - 0.00066 19.2 0.6 0.00066 19.2 0.6 2.9 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KER29443.1 - 0.026 14.4 20.3 0.36 10.8 3.5 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RAG2_PHD PF13341.6 KER29443.1 - 0.21 11.7 3.4 0.17 12.0 0.8 2.1 1 1 1 2 2 2 0 RAG2 PHD domain PHD_4 PF16866.5 KER29443.1 - 0.3 11.2 21.9 1.3 9.1 10.9 3.7 1 1 1 2 2 2 0 PHD-finger zf-MIZ PF02891.20 KER29443.1 - 5.3 6.9 16.8 16 5.3 10.5 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Mannosyl_trans2 PF04188.13 KER29444.1 - 4.6e-36 125.1 14.0 6.3e-36 124.6 14.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) RIBIOP_C PF04950.12 KER29447.1 - 1.3e-52 179.0 0.0 2.9e-51 174.7 0.0 2.5 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KER29447.1 - 1.1e-22 79.9 0.0 9e-22 77.0 0.0 2.5 3 0 0 3 3 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KER29447.1 - 0.0006 19.4 0.0 0.047 13.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KER29447.1 - 0.0096 16.3 0.1 0.063 13.7 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.14 KER29447.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 KER29447.1 - 0.017 15.2 0.1 0.11 12.6 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KER29447.1 - 0.032 14.7 0.1 0.093 13.2 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER29447.1 - 0.038 14.3 0.4 0.38 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KER29447.1 - 0.039 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KER29447.1 - 0.041 13.0 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KER29447.1 - 0.099 12.7 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KER29447.1 - 0.13 12.0 0.1 0.89 9.3 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KER29447.1 - 0.16 12.2 1.9 0.38 10.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KER29447.1 - 0.25 11.9 2.4 0.34 11.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 KER29447.1 - 0.33 10.5 2.2 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KER29447.1 - 0.4 10.9 0.0 0.4 10.9 0.0 2.6 3 0 0 3 3 1 0 AAA domain EF-hand_6 PF13405.6 KER29449.1 - 6.2e-08 32.0 0.7 0.00087 19.0 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER29449.1 - 5.8e-07 28.6 0.3 7.8e-05 22.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KER29449.1 - 8.5e-06 26.1 0.1 3.1e-05 24.3 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain pair Roc PF08477.13 KER29449.1 - 1.9e-05 24.8 0.0 5.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 KER29449.1 - 3.2e-05 23.7 0.3 0.00055 19.7 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain pair Ras PF00071.22 KER29449.1 - 0.00012 21.7 0.3 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 Ras family EF-hand_5 PF13202.6 KER29449.1 - 0.00081 18.8 0.4 0.0032 16.9 0.1 2.2 2 0 0 2 2 2 1 EF hand AAA_25 PF13481.6 KER29449.1 - 0.077 12.6 1.5 0.23 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 KER29449.1 - 0.13 12.5 2.2 0.24 11.7 0.0 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GIT_CC PF16559.5 KER29449.1 - 0.26 11.2 7.9 0.89 9.5 0.2 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_MT_bd PF06657.13 KER29449.1 - 2 9.0 15.8 0.19 12.2 1.9 3.6 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Mod_r PF07200.13 KER29449.1 - 3.1 7.9 25.4 0.05 13.7 7.0 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APH PF01636.23 KER29449.1 - 3.2 7.6 5.7 7.4 6.4 5.7 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family NPV_P10 PF05531.12 KER29449.1 - 7.3 7.1 11.0 13 6.3 1.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KER29449.1 - 8.7 6.9 28.1 0.32 11.5 15.3 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KER29452.1 - 8.6e-06 26.4 18.7 0.92 10.5 0.7 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat WH1 PF00568.23 KER29453.1 - 1.1e-10 41.4 0.0 4.3e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 WH1 domain WH1 PF00568.23 KER29455.1 - 0.00041 20.3 0.4 0.00072 19.5 0.1 1.5 2 0 0 2 2 2 1 WH1 domain DUF2076 PF09849.9 KER29455.1 - 0.002 18.2 0.3 0.0027 17.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF3573 PF12097.8 KER29455.1 - 0.17 10.7 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Forkhead_N PF08430.12 KER29455.1 - 7.6 7.1 15.9 0.43 11.2 9.5 1.9 1 1 1 2 2 2 0 Forkhead N-terminal region NEMP PF10225.9 KER29459.1 - 2.6e-09 37.1 16.3 6.2e-09 35.9 16.3 1.6 1 1 0 1 1 1 1 NEMP family PI31_Prot_C PF08577.11 KER29460.1 - 0.00026 22.1 25.9 0.00026 22.1 25.9 2.9 2 1 1 3 3 3 1 PI31 proteasome regulator RtcB PF01139.17 KER29462.1 - 3.3e-149 497.5 0.1 3.9e-149 497.3 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RRM_7 PF16367.5 KER29463.1 - 9.5e-37 125.0 0.0 1.9e-35 120.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 KER29463.1 - 3.4e-20 72.0 6.5 3.4e-20 72.0 6.5 2.9 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 KER29463.1 - 3.9e-10 39.4 0.0 4.4e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 KER29463.1 - 0.15 12.3 6.6 0.45 10.7 6.6 1.8 1 0 0 1 1 1 0 B-box zinc finger FERM_N PF09379.10 KER29464.1 - 7.7e-07 29.0 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 KER29464.1 - 0.0006 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain Di19_C PF14571.6 KER29465.1 - 3.3 8.3 7.2 2 9.0 3.5 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Androgen_recep PF02166.16 KER29466.1 - 0.034 13.0 0.2 0.055 12.3 0.2 1.2 1 0 0 1 1 1 0 Androgen receptor HEAT PF02985.22 KER29467.1 - 2.5e-14 52.1 14.5 0.0076 16.4 0.0 12.6 15 0 0 15 15 13 3 HEAT repeat RVT_1 PF00078.27 KER29467.1 - 6.1e-11 42.3 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT_2 PF13646.6 KER29467.1 - 2.4e-08 34.2 17.7 0.056 13.8 0.3 8.3 4 3 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 KER29467.1 - 4.8e-08 33.3 23.1 0.016 15.7 0.0 10.7 10 2 2 12 12 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KER29467.1 - 1.3e-05 25.7 0.0 17 6.1 0.0 6.1 5 1 1 6 6 5 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KER29467.1 - 1.6e-05 25.0 0.1 0.83 9.7 0.0 5.9 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KER29467.1 - 2.1e-05 24.2 0.1 0.00088 18.9 0.0 3.3 3 0 0 3 3 3 1 Tti2 family DUF3385 PF11865.8 KER29467.1 - 4.8e-05 23.3 1.1 1.1 9.1 0.1 6.0 6 1 0 7 7 7 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KER29467.1 - 9.3e-05 21.2 0.0 1.7 7.1 0.0 4.9 5 0 0 5 5 5 2 Adaptin N terminal region UME PF08064.13 KER29467.1 - 0.00087 19.2 3.5 1.4 8.9 0.0 5.2 5 1 1 6 6 6 1 UME (NUC010) domain RIX1 PF08167.12 KER29467.1 - 0.014 15.2 5.2 0.29 10.9 0.0 5.0 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Nop14 PF04147.12 KER29467.1 - 0.018 13.3 10.0 0.044 12.0 10.0 1.6 1 0 0 1 1 1 0 Nop14-like family Mo25 PF08569.11 KER29467.1 - 0.15 11.4 0.0 2.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Mo25-like Pes-10 PF07149.11 KER29467.1 - 3.2 6.7 9.5 6.8 5.6 9.5 1.5 1 0 0 1 1 1 0 Pes-10 zf-H2C2_2 PF13465.6 KER29469.1 - 3.3e-11 43.1 20.8 1.3e-07 31.7 1.8 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER29469.1 - 3.3e-10 39.8 26.7 1.9e-05 24.8 2.8 4.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KER29469.1 - 1.5e-06 28.0 4.0 0.00039 20.3 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KER29469.1 - 5.1e-06 26.9 20.6 0.002 18.8 1.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER29469.1 - 0.0097 16.2 4.7 0.043 14.1 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER29469.1 - 0.028 14.8 0.8 0.13 12.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zip PF02535.22 KER29470.1 - 1.7e-41 142.5 20.3 1.2e-35 123.4 7.8 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1843 PF08898.10 KER29471.1 - 0.31 11.6 0.1 0.31 11.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) PEP-utilisers_N PF05524.13 KER29471.1 - 0.73 10.0 4.6 15 5.8 0.6 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CBF PF03914.17 KER29476.1 - 1.3e-14 54.6 0.2 5.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 CBF/Mak21 family RVT_1 PF00078.27 KER29476.1 - 1.5e-10 41.0 0.0 0.00032 20.3 0.0 3.3 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.24 KER29478.1 - 9.3e-29 100.6 19.0 3.3e-28 98.7 19.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER29478.1 - 2.3e-18 66.3 17.0 2.3e-18 66.3 17.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GTP_EFTU PF00009.27 KER29479.1 - 3.2e-18 66.0 0.0 5.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER29479.1 - 0.046 13.8 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER29480.1 - 1.3e-18 67.3 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER29480.1 - 0.021 14.9 0.1 0.086 12.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase LRR_4 PF12799.7 KER29482.1 - 2.7e-08 34.0 19.6 8.7e-06 26.0 2.7 3.4 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER29482.1 - 1.2e-07 31.4 1.1 2.3e-07 30.5 1.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KER29482.1 - 1.7e-07 30.9 16.8 4.5e-05 23.1 6.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KER29482.1 - 0.11 12.6 8.7 3.2 8.0 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KER29482.1 - 4.1 8.3 14.1 48 5.1 0.2 5.2 7 0 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 KER29483.1 - 2.9e-05 23.6 0.0 0.00094 18.6 0.0 2.6 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29483.1 - 0.0087 15.4 0.0 1.6 8.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Tim54 PF11711.8 KER29483.1 - 0.71 8.6 10.6 0.41 9.4 0.9 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SpoIIIAH PF12685.7 KER29483.1 - 0.71 9.7 12.0 1.1 9.0 2.7 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Myc_N PF01056.18 KER29483.1 - 0.73 9.7 20.5 0.091 12.6 3.4 2.5 2 0 0 2 2 2 0 Myc amino-terminal region NOA36 PF06524.12 KER29483.1 - 1.9 7.8 31.0 2 7.6 4.9 2.3 2 0 0 2 2 2 0 NOA36 protein DUF4611 PF15387.6 KER29483.1 - 2.1 8.6 29.7 2.5 8.4 13.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 KER29483.1 - 3.6 7.3 21.3 1.7 8.3 3.2 2.6 2 0 0 2 2 2 0 FAM176 family CPSF100_C PF13299.6 KER29483.1 - 7.3 6.7 10.8 4.8 7.3 2.0 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BSP_II PF05432.11 KER29483.1 - 8.4 6.0 26.0 4.5 6.9 11.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PCI PF01399.27 KER29485.1 - 6.2e-12 46.0 0.0 2e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 KER29485.1 - 9.3e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 KER29485.1 - 0.00015 21.5 1.0 0.00027 20.7 1.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 KER29485.1 - 0.11 12.7 0.9 0.41 10.9 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KER29485.1 - 0.12 12.8 6.8 1.3 9.6 0.4 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KER29485.1 - 0.21 11.9 3.0 0.29 11.4 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KER29486.1 - 3.5e-58 197.0 0.0 5.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29486.1 - 5e-27 94.8 0.0 9.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KER29486.1 - 1.5e-06 28.2 0.0 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KER29486.1 - 7.8e-06 25.4 0.2 1.6e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER29486.1 - 0.068 11.9 0.0 0.17 10.6 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase fn3 PF00041.21 KER29488.1 - 1.4e-09 38.1 12.4 0.005 17.1 0.0 5.5 6 1 0 6 6 6 4 Fibronectin type III domain Interfer-bind PF09294.10 KER29488.1 - 0.0031 17.8 3.5 1.4 9.3 0.0 3.5 3 1 1 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KER29488.1 - 0.097 13.3 14.4 5.9 7.5 1.6 5.3 3 2 1 4 4 4 0 Purple acid Phosphatase, N-terminal domain SprA_N PF14349.6 KER29489.1 - 0.1 11.4 1.6 0.12 11.3 1.6 1.1 1 0 0 1 1 1 0 Motility related/secretion protein Glyco_transf_7N PF13733.6 KER29490.1 - 9.6e-23 80.3 0.0 4.3e-22 78.2 0.0 2.1 2 1 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7N PF13733.6 KER29491.1 - 5.9e-36 123.1 0.0 1e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KER29491.1 - 5.2e-21 74.1 0.1 1.2e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RNase_HII PF01351.18 KER29492.1 - 4.9e-38 131.0 0.1 6.6e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease HII 7tm_1 PF00001.21 KER29492.1 - 0.0026 17.2 1.8 0.004 16.5 1.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.27 KER29495.1 - 3.3e-07 30.1 0.0 6.4e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1343 PF07075.11 KER29495.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) MH2 PF03166.14 KER29497.1 - 2.2e-64 217.1 0.0 2.9e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KER29497.1 - 2.9e-39 133.4 0.6 4.8e-39 132.7 0.6 1.4 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 KER29497.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 AAA_6 PF12774.7 KER29498.1 - 9e-157 521.1 0.0 7.2e-155 514.9 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KER29498.1 - 8.5e-118 394.4 13.3 8.5e-118 394.4 13.3 3.3 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 KER29498.1 - 1.9e-96 322.4 0.0 5.8e-96 320.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER29498.1 - 4.5e-81 272.4 0.2 1.9e-80 270.4 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 KER29498.1 - 3.3e-74 250.4 6.3 1.2e-63 215.6 1.9 5.4 4 1 1 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 KER29498.1 - 1.6e-73 246.0 0.5 2e-68 229.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_9 PF12781.7 KER29498.1 - 4e-72 241.9 2.1 2.7e-69 232.7 1.7 4.0 2 1 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 KER29498.1 - 9.6e-51 172.8 9.4 2.9e-50 171.3 8.0 2.5 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 KER29498.1 - 6.2e-43 145.7 0.0 4e-42 143.1 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KER29498.1 - 9.7e-29 100.3 0.6 1.7e-24 86.5 0.0 3.2 2 1 1 3 3 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER29498.1 - 1.5e-25 89.8 0.2 4.3e-06 26.8 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER29498.1 - 7.5e-18 64.6 0.1 4.9e-17 62.0 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KER29498.1 - 1.7e-15 57.3 0.0 1e-14 54.8 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KER29498.1 - 1.2e-08 35.4 0.7 0.024 14.9 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KER29498.1 - 4.2e-08 33.8 1.0 0.14 12.5 0.0 6.4 5 1 0 5 5 4 1 AAA ATPase domain AAA PF00004.29 KER29498.1 - 1.6e-06 28.6 0.1 1.9 8.9 0.3 5.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KER29498.1 - 0.0013 19.3 0.0 0.31 11.6 0.0 4.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KER29498.1 - 0.0022 17.1 0.0 2.7 7.0 0.0 2.9 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 KER29498.1 - 0.013 15.3 0.1 14 5.4 0.1 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 KER29498.1 - 0.019 14.7 0.7 14 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KER29498.1 - 0.077 13.4 0.1 56 4.2 0.1 3.8 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 KER29498.1 - 0.12 12.1 0.1 7.7 6.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Tape_meas_lam_C PF09718.10 KER29498.1 - 0.22 11.7 2.2 0.56 10.4 0.2 2.9 3 0 0 3 3 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ATPase_2 PF01637.18 KER29498.1 - 0.27 11.1 4.8 10 6.0 0.1 5.0 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea DUF853 PF05872.12 KER29498.1 - 0.29 9.7 3.7 8.1 4.9 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Cep57_CLD_2 PF14197.6 KER29498.1 - 0.58 10.3 15.8 0.053 13.6 6.9 3.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ATPase PF06745.13 KER29498.1 - 0.82 9.0 4.0 3.7 6.8 0.0 3.8 4 0 0 4 4 4 0 KaiC DUF948 PF06103.11 KER29498.1 - 1.2 9.4 9.7 22 5.4 0.0 5.9 5 1 1 6 6 5 0 Bacterial protein of unknown function (DUF948) AAA_33 PF13671.6 KER29498.1 - 2.2 8.4 7.8 29 4.8 0.1 5.0 5 0 0 5 5 5 0 AAA domain DUF5595 PF18077.1 KER29498.1 - 2.6 8.2 5.8 30 4.8 1.9 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DUF4375 PF14300.6 KER29498.1 - 4 7.7 5.5 61 3.9 0.1 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) ABC_tran PF00005.27 KER29498.1 - 5.3 7.5 8.1 5.4 7.5 0.1 4.5 5 0 0 5 5 4 0 ABC transporter Ldh_1_C PF02866.18 KER29499.1 - 1.8e-06 28.0 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DUF316 PF03761.15 KER29499.1 - 0.026 14.1 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 BTB_2 PF02214.22 KER29500.1 - 1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 KER29500.1 - 3.4e-24 85.4 13.5 7.1e-24 84.4 13.5 1.5 1 1 1 2 2 2 1 Ion transport protein BTB_3 PF16017.5 KER29500.1 - 1.2e-05 25.3 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Shal-type PF11601.8 KER29500.1 - 6e-05 22.5 1.4 0.00011 21.7 1.4 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal Ion_trans_2 PF07885.16 KER29500.1 - 0.028 14.4 5.7 0.028 14.4 5.7 2.7 3 0 0 3 3 3 0 Ion channel Filament PF00038.21 KER29502.1 - 0.18 11.3 35.6 0.51 9.9 8.9 3.2 2 1 1 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 KER29502.1 - 0.85 10.0 35.9 0.34 11.3 20.9 2.4 1 1 1 2 2 2 0 Fez1 DUF5446 PF17522.2 KER29502.1 - 1.9 8.7 22.9 1.1 9.5 5.3 4.1 3 2 1 4 4 4 0 Family of unknown function (DUF5446) Spc7 PF08317.11 KER29502.1 - 2.3 7.0 40.3 0.012 14.5 11.4 3.8 3 1 0 4 4 4 0 Spc7 kinetochore protein DUF4250 PF14056.6 KER29502.1 - 5.6 7.0 7.6 15 5.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) GAS PF13851.6 KER29502.1 - 7.8 5.8 34.7 1.8 7.9 11.3 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 KER29502.1 - 9.2 6.0 33.5 0.4 10.5 10.0 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family zf-C2H2 PF00096.26 KER29504.1 - 0.00085 19.6 25.1 0.0026 18.1 6.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER29504.1 - 0.0011 19.6 22.6 0.039 14.8 4.7 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER29504.1 - 0.013 15.8 7.2 1 9.7 0.5 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KER29504.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.6 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_5 PF13719.6 KER29504.1 - 0.98 9.2 4.3 6.8 6.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KER29504.1 - 1.6 8.7 4.1 56 3.8 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain RVT_1 PF00078.27 KER29505.1 - 7.2e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIY-YIG PF01541.24 KER29505.1 - 1.3e-06 28.6 0.6 0.038 14.3 0.1 2.6 2 0 0 2 2 2 2 GIY-YIG catalytic domain AbiEi_3 PF11459.8 KER29505.1 - 0.0023 17.6 0.1 3.2 7.4 0.0 2.7 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Laminin_N PF00055.17 KER29505.1 - 0.033 13.8 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Laminin N-terminal (Domain VI) Herpes_UL49_2 PF04823.12 KER29505.1 - 0.041 14.0 0.9 35 4.6 0.0 3.9 4 0 0 4 4 4 0 Herpesvirus UL49 tegument protein TetR_N PF00440.23 KER29505.1 - 0.079 12.8 0.2 23 4.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family zinc_ribbon_6 PF14599.6 KER29505.1 - 0.085 12.9 3.2 6.8 6.8 0.2 2.8 2 0 0 2 2 2 0 Zinc-ribbon DUF4346 PF14251.6 KER29505.1 - 0.098 12.7 0.1 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) HupH_C PF04809.13 KER29505.1 - 0.1 12.3 0.0 3.9 7.2 0.0 3.2 3 0 0 3 3 3 0 HupH hydrogenase expression protein, C-terminal conserved region Pre-PUA PF17832.1 KER29505.1 - 0.11 13.1 0.0 0.52 11.0 0.0 2.2 1 0 0 1 1 1 0 Pre-PUA-like domain MOZ_SAS PF01853.18 KER29506.1 - 9.2e-69 230.7 0.1 1.6e-68 229.9 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KER29506.1 - 4e-18 64.8 0.7 1.3e-17 63.2 0.7 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 KER29506.1 - 1.3e-14 53.8 15.6 4e-09 36.2 3.6 2.9 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 KER29506.1 - 4.2e-05 23.6 15.5 0.001 19.1 2.2 2.8 1 1 1 2 2 2 2 PHD-finger Vps36-NZF-N PF16988.5 KER29506.1 - 1.4 8.3 6.0 0.4 10.1 0.1 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RVT_1 PF00078.27 KER29508.1 - 2.4e-19 69.7 0.0 3.2e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ARID PF01388.21 KER29508.1 - 1.2e-10 41.9 0.0 6.7e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Baculo_VP39 PF04501.12 KER29508.1 - 0.19 11.2 0.0 3.6 7.0 0.0 2.3 1 1 1 2 2 2 0 Baculovirus major capsid protein VP39 DUF3110 PF11360.8 KER29508.1 - 0.28 11.4 0.9 51 4.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3110) Pkinase PF00069.25 KER29510.1 - 9.2e-39 133.4 0.0 1.4e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER29510.1 - 1.5e-17 63.8 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER29510.1 - 4.6e-08 32.7 0.0 1.5e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KER29510.1 - 0.00084 18.4 0.3 0.0016 17.5 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER29510.1 - 0.0088 16.0 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER29510.1 - 0.12 11.8 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER29510.1 - 0.15 10.8 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Neur_chan_LBD PF02931.23 KER29511.1 - 3.9e-46 157.2 0.5 6e-46 156.6 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER29511.1 - 1.6e-24 87.3 0.2 1.3e-19 71.2 1.5 2.5 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region L_HMGIC_fpl PF10242.9 KER29512.1 - 4.6e-28 98.7 9.2 3.2e-26 92.7 9.2 2.1 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 KER29512.1 - 3.3e-09 36.8 1.4 6.8e-09 35.8 1.4 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.25 KER29513.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KER29514.1 - 2.6e-25 89.3 0.0 9.1e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER29514.1 - 2.6e-12 46.6 0.0 2e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KER29514.1 - 0.11 11.8 0.0 0.99 8.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like DUF1387 PF07139.11 KER29515.1 - 4.7e-07 29.8 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) Methyltransf_11 PF08241.12 KER29515.1 - 1.2e-05 25.9 0.0 3.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER29515.1 - 0.041 13.7 0.0 0.82 9.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain ARA70 PF12489.8 KER29515.1 - 0.67 10.2 4.7 0.44 10.7 0.1 3.0 2 1 1 3 3 3 0 Nuclear coactivator PP2C PF00481.21 KER29517.1 - 5e-23 82.1 0.0 1.7e-22 80.3 0.0 1.8 3 0 0 3 3 3 1 Protein phosphatase 2C CUE PF02845.16 KER29518.1 - 0.00091 18.9 0.0 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 KER29518.1 - 0.0075 15.8 1.1 0.014 14.9 0.1 1.9 2 0 0 2 2 2 1 DMRTA motif Complex1_LYR PF05347.15 KER29519.1 - 6.5e-08 32.5 0.1 9.2e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Dimer_Tnp_hAT PF05699.14 KER29520.1 - 0.017 14.9 7.1 2.2 8.1 0.4 3.5 3 0 0 3 3 3 0 hAT family C-terminal dimerisation region PUMA PF15826.5 KER29520.1 - 3.3 7.9 10.0 46 4.1 0.2 4.2 4 0 0 4 4 4 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis TPR_1 PF00515.28 KER29521.1 - 2e-08 33.7 1.9 0.043 13.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER29521.1 - 5.8e-08 32.3 1.8 0.00085 19.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER29521.1 - 0.00031 20.7 0.1 0.031 14.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER29521.1 - 0.00033 20.8 0.2 0.0017 18.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER29521.1 - 0.002 18.8 1.4 0.013 16.3 0.5 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER29521.1 - 0.0024 18.3 0.3 0.011 16.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Synaphin PF05835.12 KER29521.1 - 0.0037 17.6 0.3 0.008 16.5 0.3 1.5 1 0 0 1 1 1 1 Synaphin protein TPR_12 PF13424.6 KER29521.1 - 0.012 15.9 0.3 0.87 9.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER29521.1 - 0.016 14.9 0.2 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KER29521.1 - 0.021 15.5 0.1 0.021 15.5 0.1 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KER29521.1 - 0.029 14.5 0.4 0.098 12.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER29521.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.18 KER29521.1 - 0.08 13.0 0.0 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain tRNA-synt_2b PF00587.25 KER29522.1 - 1.2e-16 61.2 0.0 2.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_2 PF07719.17 KER29522.1 - 9.7e-13 47.2 6.9 1.1e-05 25.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER29522.1 - 2.3e-09 36.7 7.0 0.0022 17.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER29522.1 - 1.6e-08 34.7 0.4 0.23 12.4 0.1 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER29522.1 - 3.5e-08 33.0 3.9 0.038 14.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER29522.1 - 1e-06 28.9 0.9 0.0018 18.5 0.0 4.3 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KER29522.1 - 1.1e-05 25.1 0.5 2.4 8.4 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER29522.1 - 2e-05 25.1 0.5 0.00089 19.9 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER29522.1 - 2.2e-05 24.5 0.8 0.2 12.1 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER29522.1 - 3.2e-05 24.4 0.3 0.2 12.2 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER29522.1 - 0.0001 21.9 0.1 0.16 11.7 0.0 4.3 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 KER29522.1 - 0.00031 20.8 0.5 0.0084 16.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER29522.1 - 0.0015 18.7 4.6 0.004 17.4 0.9 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KER29522.1 - 0.0072 16.9 1.6 33 5.4 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat PPR PF01535.20 KER29522.1 - 0.41 11.0 2.9 54 4.4 0.0 4.7 5 0 0 5 5 5 0 PPR repeat CBM26 PF16738.5 KER29525.1 - 0.028 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Starch-binding module 26 LapA_dom PF06305.11 KER29525.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vinculin PF01044.19 KER29528.1 - 6.9e-132 441.7 10.6 8.9e-132 441.3 10.6 1.0 1 0 0 1 1 1 1 Vinculin family Nmad5 PF18757.1 KER29528.1 - 0.033 14.4 0.5 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 DUF948 PF06103.11 KER29528.1 - 0.13 12.6 2.2 25 5.2 0.1 3.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) MCM_bind PF09739.9 KER29529.1 - 1.5e-81 274.6 0.1 2.4e-60 204.6 0.8 2.7 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor RabGAP-TBC PF00566.18 KER29530.1 - 6.9e-25 88.0 12.0 2.7e-13 50.1 0.3 4.1 3 1 0 3 3 3 3 Rab-GTPase-TBC domain RUN PF02759.19 KER29530.1 - 5e-23 81.6 0.0 2.4e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 RUN domain PH_RBD PF12068.8 KER29530.1 - 1.3e-18 67.1 0.3 4.2e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Rab-binding domain (RBD) Pou PF00157.17 KER29531.1 - 4.8e-22 77.7 0.7 8.7e-22 76.9 0.7 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KER29531.1 - 2.7e-13 49.5 0.0 6.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KER29531.1 - 2.7e-05 24.4 1.5 0.00035 20.8 0.3 2.8 2 1 1 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 KER29531.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.22 KER29531.1 - 0.025 14.6 0.4 0.71 10.0 0.2 3.2 3 1 0 3 3 3 0 Helix-turn-helix SAP30_Sin3_bdg PF13867.6 KER29531.1 - 0.15 12.4 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 MFS_2 PF13347.6 KER29532.1 - 1.4e-16 60.1 18.9 1.1e-10 40.7 10.4 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KER29532.1 - 9.4e-11 41.2 17.1 9.1e-08 31.4 4.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily COG5 PF10392.9 KER29533.1 - 8.1e-17 61.6 5.9 3.4e-16 59.6 5.9 2.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KER29533.1 - 4.9e-05 23.3 0.3 0.00047 20.2 0.5 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Baculo_PEP_C PF04513.12 KER29533.1 - 0.13 12.2 2.3 0.36 10.9 0.2 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4919 PF16266.5 KER29534.1 - 0.13 12.2 0.2 0.19 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) 7tm_1 PF00001.21 KER29535.1 - 6.5e-22 78.1 22.7 2.3e-20 73.0 22.7 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PMT_2 PF13231.6 KER29535.1 - 0.009 16.2 0.1 0.009 16.2 0.1 3.5 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CitMHS PF03600.16 KER29535.1 - 0.9 8.7 5.3 18 4.4 5.3 2.7 1 1 0 1 1 1 0 Citrate transporter RVT_1 PF00078.27 KER29536.1 - 5.2e-23 81.7 0.0 6.5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 KER29537.1 - 1.1e-18 67.4 0.0 2.3e-17 63.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER29537.1 - 5e-08 32.8 0.0 8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KER29537.1 - 6.1e-05 22.6 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KER29537.1 - 0.00044 20.2 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Nucleo_P87 PF07267.11 KER29538.1 - 0.05 12.5 0.6 0.061 12.2 0.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Phage_GPO PF05929.11 KER29538.1 - 0.065 12.8 0.9 0.1 12.2 0.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RVT_1 PF00078.27 KER29539.1 - 2.7e-07 30.3 0.5 9.3e-06 25.3 0.1 2.9 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) mTERF PF02536.14 KER29539.1 - 0.0076 15.2 0.9 0.016 14.1 0.9 1.5 1 0 0 1 1 1 1 mTERF ABC_membrane PF00664.23 KER29540.1 - 3.1e-92 309.1 33.2 1.9e-60 204.9 8.5 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KER29540.1 - 5.2e-68 227.8 0.1 6.1e-36 124.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KER29540.1 - 1.1e-14 54.5 1.0 0.00022 20.7 0.1 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KER29540.1 - 6.4e-11 42.9 2.1 0.00029 21.3 0.5 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KER29540.1 - 1.9e-10 41.2 0.3 0.0013 19.0 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KER29540.1 - 3.1e-09 37.1 0.0 0.028 14.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KER29540.1 - 5.4e-09 35.4 0.2 0.0014 17.5 0.0 2.6 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KER29540.1 - 6.3e-09 36.0 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KER29540.1 - 3.2e-08 33.1 0.0 0.0049 16.2 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 KER29540.1 - 4.4e-08 33.2 0.0 0.01 15.8 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 KER29540.1 - 8.9e-08 31.8 0.1 0.0038 16.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KER29540.1 - 6.6e-07 29.2 0.6 0.03 14.0 0.6 3.4 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KER29540.1 - 7.3e-07 28.9 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KER29540.1 - 3.2e-06 27.8 0.4 0.032 14.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain G-alpha PF00503.20 KER29540.1 - 4.7e-06 26.0 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 KER29540.1 - 4.9e-06 27.0 0.1 0.26 11.7 0.0 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER29540.1 - 7e-06 26.1 0.0 0.12 12.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KER29540.1 - 4.5e-05 23.6 9.5 0.033 14.4 0.3 4.9 4 2 0 4 4 3 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KER29540.1 - 6.6e-05 23.5 0.0 0.45 11.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 KER29540.1 - 0.00017 21.6 0.0 0.99 9.3 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain MMR_HSR1 PF01926.23 KER29540.1 - 0.00031 20.8 0.0 0.52 10.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KER29540.1 - 0.00064 19.8 0.0 1.9 8.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 KER29540.1 - 0.001 18.8 0.4 1.6 8.5 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein NB-ARC PF00931.22 KER29540.1 - 0.0011 18.3 0.0 2.1 7.4 0.0 2.8 4 0 0 4 4 2 2 NB-ARC domain DUF815 PF05673.13 KER29540.1 - 0.0015 17.8 0.0 0.68 9.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KER29540.1 - 0.0021 18.0 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 KER29540.1 - 0.0022 17.6 1.1 1.5 8.4 0.3 3.5 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KER29540.1 - 0.0023 18.1 0.2 0.62 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KER29540.1 - 0.0055 17.1 0.1 5.3 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KER29540.1 - 0.0063 16.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KER29540.1 - 0.0067 16.7 0.0 6.8 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KER29540.1 - 0.014 14.8 0.1 9.8 5.5 0.0 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Roc PF08477.13 KER29540.1 - 0.014 15.6 0.0 8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 KER29540.1 - 0.015 15.0 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase PRK PF00485.18 KER29540.1 - 0.016 15.0 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 KER29540.1 - 0.02 14.5 0.1 8.7 5.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 KER29540.1 - 0.024 14.5 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase TsaE PF02367.17 KER29540.1 - 0.042 13.9 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SART-1 PF03343.13 KER29540.1 - 0.042 12.4 3.4 4.8 5.6 0.0 2.1 1 1 1 2 2 2 0 SART-1 family Viral_helicase1 PF01443.18 KER29540.1 - 0.058 13.1 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 KER29540.1 - 0.072 13.2 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 KER29540.1 - 0.087 12.5 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Ploopntkinase3 PF18751.1 KER29540.1 - 0.087 12.7 0.0 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 KER29540.1 - 0.097 12.6 0.0 7.4 6.5 0.0 2.9 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KER29540.1 - 0.12 12.8 2.7 28 5.1 0.1 3.7 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 KER29540.1 - 0.13 12.0 0.6 9.3 6.0 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KER29540.1 - 0.15 11.7 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 KER29540.1 - 0.15 12.1 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family DUF2208 PF09973.9 KER29540.1 - 0.52 9.9 5.7 1.3 8.6 5.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) TLP1_add_C PF18313.1 KER29541.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Mitofilin PF09731.9 KER29542.1 - 7.9e-71 239.7 12.5 9.1e-53 180.0 3.3 3.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF357 PF04010.13 KER29542.1 - 0.12 12.5 0.2 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) HTH_psq PF05225.16 KER29544.1 - 5.8e-11 41.9 0.1 9.4e-10 38.1 0.0 2.8 3 0 0 3 3 3 1 helix-turn-helix, Psq domain Nop16 PF09420.10 KER29545.1 - 1.5e-19 70.9 2.3 3.8e-13 49.9 0.1 2.2 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 LIM PF00412.22 KER29545.1 - 0.074 13.3 1.4 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 LIM domain Prefoldin PF02996.17 KER29546.1 - 6.5e-26 90.6 3.3 9e-26 90.1 3.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 KER29546.1 - 1.1 9.5 7.7 0.14 12.4 0.6 2.7 2 1 0 2 2 2 0 Osmosensory transporter coiled coil zf-rbx1 PF12678.7 KER29547.1 - 9.9e-05 22.6 5.0 9.9e-05 22.6 5.0 4.0 4 1 0 4 4 4 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KER29547.1 - 0.00041 20.6 7.6 0.00041 20.6 7.6 5.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KER29547.1 - 0.00074 19.3 6.4 0.00074 19.3 6.4 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRXRR PF14239.6 KER29547.1 - 0.35 10.7 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 RRXRR protein Dynactin_p22 PF07426.11 KER29549.1 - 1.8e-34 119.0 6.9 1.8e-34 119.0 6.9 1.8 2 0 0 2 2 2 1 Dynactin subunit p22 UQ_con PF00179.26 KER29549.1 - 7.2e-27 93.8 0.0 1.3e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NDUFV3 PF15880.5 KER29549.1 - 5.5e-06 26.3 2.1 7.5e-06 25.9 0.8 1.9 2 0 0 2 2 2 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial ROF PF07073.12 KER29549.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) TRPM_tetra PF16519.5 KER29549.1 - 0.15 12.2 3.3 10 6.3 0.3 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Pan3_PK PF18101.1 KER29550.1 - 2.4e-44 150.7 1.1 5.4e-43 146.3 0.4 2.7 2 0 0 2 2 2 1 Pan3 Pseudokinase domain DUF3543 PF12063.8 KER29550.1 - 0.25 10.7 2.4 0.4 10.0 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Prismane PF03063.20 KER29552.1 - 0.0026 16.6 4.8 0.0038 16.0 4.8 1.2 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family IQ PF00612.27 KER29552.1 - 0.069 13.0 2.0 0.2 11.5 2.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif NPV_P10 PF05531.12 KER29552.1 - 0.77 10.3 6.8 5.6 7.5 0.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KER29552.1 - 0.83 9.8 15.0 0.95 9.6 0.5 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KER29552.1 - 0.93 9.6 25.4 2.3 8.3 13.3 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spectrin PF00435.21 KER29552.1 - 2.8 8.5 15.0 14 6.2 7.4 2.9 2 1 0 2 2 2 0 Spectrin repeat FUSC PF04632.12 KER29552.1 - 3.4 6.1 5.1 0.43 9.1 1.3 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Cep57_MT_bd PF06657.13 KER29552.1 - 7.7 7.0 14.5 0.2 12.1 1.9 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SET PF00856.28 KER29554.1 - 4.6e-19 69.4 0.0 5.1e-18 66.0 0.0 2.9 3 0 0 3 3 3 1 SET domain PWWP PF00855.17 KER29554.1 - 1.4e-16 60.6 0.2 3e-15 56.4 0.1 2.5 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 KER29554.1 - 6e-10 38.9 60.5 1.3e-05 25.0 2.5 6.6 5 2 1 6 6 6 5 PHD-finger C5HCH PF17982.1 KER29554.1 - 2.1e-06 27.8 5.6 2.1e-06 27.8 5.6 5.3 5 1 0 5 5 5 1 NSD Cys-His rich domain C1_1 PF00130.22 KER29554.1 - 0.00078 19.3 5.9 0.00078 19.3 5.9 6.9 5 3 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KER29554.1 - 0.0013 19.0 2.3 0.0013 19.0 2.3 4.8 4 2 1 5 5 5 1 FYVE-type zinc finger EMP24_GP25L PF01105.24 KER29555.1 - 1.7e-16 60.7 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tmemb_cc2 PF10267.9 KER29555.1 - 0.029 13.5 0.0 0.029 13.5 0.0 1.9 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein SYCP2_SLD PF18584.1 KER29556.1 - 1.1e-05 25.6 0.0 3.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Synaptonemal complex 2 Spt16M-like domain TRAM_LAG1_CLN8 PF03798.16 KER29557.1 - 1.4e-25 90.2 9.5 1.4e-25 90.2 9.5 1.9 2 0 0 2 2 2 1 TLC domain DUF3307 PF11750.8 KER29557.1 - 0.00015 21.8 0.3 0.00024 21.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) IFRD PF05004.13 KER29559.1 - 2.4e-48 164.8 0.0 3.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 KER29559.1 - 1e-11 45.2 1.3 1e-11 45.2 1.3 2.3 2 0 0 2 2 2 1 Interferon-related protein conserved region Retrotrans_gag PF03732.17 KER29559.1 - 0.0021 18.3 0.1 0.033 14.4 0.0 2.7 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KER29559.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KER29559.1 - 0.072 12.8 0.3 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Ribosomal_S27e PF01667.17 KER29559.1 - 0.44 10.3 2.8 1.1 9.0 2.8 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 UBA PF00627.31 KER29563.1 - 0.12 12.3 0.5 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 UBA/TS-N domain ZZ PF00569.17 KER29563.1 - 1 9.3 7.5 1.9 8.4 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Nuc_sug_transp PF04142.15 KER29564.1 - 9.8e-90 300.9 15.1 1.2e-89 300.6 15.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KER29564.1 - 7.1e-07 29.5 32.2 0.00015 21.9 11.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KER29564.1 - 5.1e-05 22.7 8.7 5.1e-05 22.7 8.7 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KER29564.1 - 0.0014 18.0 12.3 0.0054 16.1 2.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KER29564.1 - 0.034 13.4 14.9 0.031 13.5 1.8 2.6 1 1 1 2 2 2 0 UAA transporter family EmrE PF13536.6 KER29564.1 - 2.8 7.4 16.3 0.052 13.1 0.8 2.6 1 1 2 3 3 3 0 Putative multidrug resistance efflux transporter G-alpha PF00503.20 KER29565.1 - 2.2e-104 349.5 0.8 2.9e-104 349.0 0.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER29565.1 - 6.5e-14 51.8 0.5 9e-09 35.0 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER29565.1 - 0.0001 21.7 0.6 0.14 11.5 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KER29565.1 - 0.032 14.5 0.1 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KER29565.1 - 0.049 13.0 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KER29565.1 - 0.069 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KER29565.1 - 0.075 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 KER29565.1 - 0.12 11.5 0.3 0.19 10.9 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TOH_N PF12549.8 KER29566.1 - 0.01 15.7 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal 14-3-3 PF00244.20 KER29567.1 - 6.7e-86 287.4 1.9 7.7e-86 287.2 1.9 1.0 1 0 0 1 1 1 1 14-3-3 protein 14-3-3 PF00244.20 KER29569.1 - 3.8e-41 141.0 4.2 4.4e-41 140.8 4.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4208 PF13907.6 KER29569.1 - 0.0044 17.4 1.3 0.0088 16.5 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Cadherin PF00028.17 KER29570.1 - 2.2e-57 191.5 11.3 1.1e-13 51.5 0.1 9.0 7 2 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER29570.1 - 1.6e-10 40.7 0.1 0.02 14.7 0.0 5.8 6 0 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 KER29570.1 - 0.00049 20.4 0.1 0.23 11.8 0.0 4.2 5 0 0 5 5 5 1 RET Cadherin like domain 1 LRR_4 PF12799.7 KER29571.1 - 5.1e-45 150.7 109.6 9.5e-08 32.2 1.8 16.1 11 5 5 17 17 17 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER29571.1 - 1.3e-42 145.2 41.2 1.8e-12 47.1 0.1 10.3 4 4 5 10 10 10 10 Leucine-rich repeat LRR_8 PF13855.6 KER29571.1 - 4.1e-34 116.1 79.9 1.4e-09 37.5 1.3 11.1 6 4 6 12 12 12 11 Leucine rich repeat Hemerythrin PF01814.23 KER29572.1 - 0.061 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Globin PF00042.22 KER29574.1 - 2.2e-14 53.9 0.1 4.8e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Globin Oxysterol_BP PF01237.18 KER29575.1 - 5e-125 417.2 0.0 6.9e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_6 PF15406.6 KER29575.1 - 0.00014 22.1 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER29575.1 - 0.0023 18.4 0.0 0.007 16.9 0.0 1.9 1 0 0 1 1 1 1 PH domain QVR PF17064.5 KER29576.1 - 6.4e-07 29.5 5.9 9.3e-07 29.0 5.9 1.2 1 0 0 1 1 1 1 Sleepless protein CxC2 PF18803.1 KER29576.1 - 0.022 14.9 0.2 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Ribosomal_S15 PF00312.22 KER29577.1 - 0.067 13.4 2.2 0.21 11.8 0.9 2.2 2 0 0 2 2 2 0 Ribosomal protein S15 zf-C4 PF00105.18 KER29578.1 - 2.7e-29 101.4 19.2 6.1e-29 100.3 19.2 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER29578.1 - 1.6e-28 99.8 2.3 5.2e-15 55.6 0.8 2.4 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor GHMP_kinases_N PF00288.26 KER29578.1 - 0.044 14.0 0.9 0.1 12.8 0.9 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain Shadoo PF14999.6 KER29578.1 - 3 8.0 6.2 4.2 7.5 4.4 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Cadherin PF00028.17 KER29580.1 - 6.1e-49 164.4 0.3 8.6e-19 67.8 0.1 5.7 5 1 0 5 5 5 5 Cadherin domain Cadherin_3 PF16184.5 KER29580.1 - 6.5e-06 26.1 0.7 2.6 8.1 0.1 5.8 6 0 0 6 6 6 3 Cadherin-like Cadherin_pro PF08758.11 KER29580.1 - 0.0053 16.9 0.1 4.5 7.5 0.0 3.7 4 0 0 4 4 4 2 Cadherin prodomain like 7TM_GPCR_Srx PF10328.9 KER29581.1 - 1.2e-05 25.1 9.5 1.2e-05 25.1 9.5 1.8 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 KER29581.1 - 1.3e-05 24.7 10.3 1.9e-05 24.1 10.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COesterase PF00135.28 KER29582.1 - 3.9e-90 303.2 0.0 5.3e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER29582.1 - 0.0018 18.1 0.0 0.95 9.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF4471 PF14740.6 KER29583.1 - 2.6e-84 283.1 0.0 2.5e-76 256.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 KER29583.1 - 0.082 13.1 0.1 0.29 11.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) DUF4470 PF14737.6 KER29584.1 - 4.2e-11 42.9 0.0 4.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Peptidase_M15_3 PF08291.11 KER29584.1 - 0.0029 17.7 0.0 0.003 17.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase M15 RB_A PF01858.17 KER29585.1 - 1e-61 208.2 0.5 2.9e-61 206.7 0.5 1.9 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 KER29585.1 - 7e-43 145.8 3.7 1.3e-40 138.5 0.6 2.5 2 0 0 2 2 2 2 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 KER29585.1 - 1e-33 115.8 0.8 2.9e-33 114.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) DNA_pol3_delta PF06144.13 KER29585.1 - 0.2 11.4 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ECH_1 PF00378.20 KER29589.1 - 2.7e-96 321.7 2.4 2.9e-53 180.7 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER29589.1 - 2.3e-57 195.0 4.9 4.1e-28 98.8 0.1 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase BLOC1_2 PF10046.9 KER29590.1 - 7.7e-22 77.4 2.1 9.4e-22 77.1 2.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 KER29590.1 - 0.00021 21.3 0.5 0.00071 19.6 0.1 2.1 2 1 0 2 2 2 1 Tetramerisation domain of TRPM SOG2 PF10428.9 KER29590.1 - 0.0024 17.2 1.8 0.0027 17.0 1.8 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein TelA PF05816.11 KER29590.1 - 0.0024 17.0 0.3 0.0029 16.7 0.3 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Baculo_PEP_C PF04513.12 KER29590.1 - 0.0043 17.1 0.9 0.0068 16.5 0.6 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 KER29590.1 - 0.011 15.8 1.5 0.014 15.5 1.5 1.2 1 0 0 1 1 1 0 Tropomyosin like Lebercilin PF15619.6 KER29590.1 - 0.015 14.9 2.9 0.031 14.0 2.9 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Med4 PF10018.9 KER29590.1 - 0.021 14.5 3.6 0.029 14.1 3.6 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0184 PF03670.13 KER29590.1 - 0.025 14.9 2.4 0.84 10.1 0.4 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) WXG100 PF06013.12 KER29590.1 - 0.027 14.7 2.6 3.2 8.0 0.0 2.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG XhlA PF10779.9 KER29590.1 - 0.049 13.8 1.6 0.13 12.5 1.6 1.9 1 1 0 1 1 1 0 Haemolysin XhlA Spc7 PF08317.11 KER29590.1 - 0.051 12.5 2.9 0.061 12.2 2.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RAC_head PF16717.5 KER29590.1 - 0.075 14.0 0.8 0.11 13.5 0.8 1.2 1 0 0 1 1 1 0 Ribosome-associated complex head domain Fib_alpha PF08702.10 KER29590.1 - 0.078 13.2 1.0 0.099 12.8 1.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 KER29590.1 - 0.085 13.0 0.6 0.18 11.9 0.6 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 KER29590.1 - 0.15 12.1 0.8 0.34 11.0 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KER29590.1 - 0.17 12.3 0.7 1 9.8 0.1 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1478 PF07349.11 KER29591.1 - 0.044 13.7 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) SOUL PF04832.12 KER29594.1 - 6e-41 140.4 0.2 9e-41 139.8 0.2 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein RVT_1 PF00078.27 KER29594.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SOUL PF04832.12 KER29595.1 - 6.4e-43 146.8 0.1 7.1e-43 146.7 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein RVT_1 PF00078.27 KER29596.1 - 8.9e-14 51.5 0.0 2.9e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_1 PF00583.25 KER29596.1 - 3.4e-05 24.1 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KER29596.1 - 0.053 13.6 0.0 2.4 8.2 0.0 2.9 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 KER29597.1 - 5.1e-16 58.9 0.0 9.3e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_fiss_reg PF05308.11 KER29597.1 - 3.6e-10 40.3 1.0 1e-09 38.9 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial fission regulator MAD PF05557.13 KER29597.1 - 0.18 10.2 0.2 0.27 9.5 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein BNR_2 PF13088.6 KER29598.1 - 0.0048 16.2 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain Stathmin PF00836.19 KER29599.1 - 0.0029 17.6 27.1 0.0075 16.2 16.6 2.1 1 1 1 2 2 2 2 Stathmin family IF-2B PF01008.17 KER29599.1 - 0.28 10.3 7.8 0.2 10.8 6.5 1.3 1 1 0 1 1 1 0 Initiation factor 2 subunit family Exonuc_VII_L PF02601.15 KER29599.1 - 0.53 9.8 15.0 0.75 9.3 15.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 KER29599.1 - 0.65 7.4 22.0 0.82 7.1 22.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mit_KHE1 PF10173.9 KER29599.1 - 1.5 8.9 7.9 2.1 8.4 7.9 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Neur_chan_memb PF02932.16 KER29599.1 - 2 8.4 11.6 2.8 8.0 11.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ZYG-11_interact PF05884.12 KER29599.1 - 4.7 6.5 4.1 5.7 6.3 4.1 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Alb1 PF09135.11 KER29599.1 - 6.3 7.7 20.6 2.3 9.1 7.5 2.2 1 1 1 2 2 2 0 Alb1 Sec2p PF06428.11 KER29601.1 - 1.8e-07 31.0 3.5 1.8e-07 31.0 3.5 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 KER29601.1 - 2.3 8.4 9.9 10 6.3 1.2 3.4 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 KER29601.1 - 8.2 6.6 8.5 6.4 6.9 0.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper CTNNBL PF08216.11 KER29602.1 - 4.5e-30 103.9 0.0 1.1e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DJ-1_PfpI PF01965.24 KER29602.1 - 2.6e-26 92.4 0.1 3.8e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KER29602.1 - 0.02 14.6 0.0 0.24 11.1 0.0 2.1 1 1 1 2 2 2 0 ThiJ/PfpI family-like RIH_assoc PF08454.11 KER29602.1 - 0.12 12.2 0.2 1.3 8.9 0.0 2.6 2 1 0 2 2 2 0 RyR and IP3R Homology associated MAD PF05557.13 KER29603.1 - 5e-33 114.4 4.3 5e-33 114.4 4.3 3.8 2 1 1 3 3 3 1 Mitotic checkpoint protein PspB PF06667.12 KER29603.1 - 0.035 14.2 0.3 0.035 14.2 0.3 4.1 4 1 1 5 5 5 0 Phage shock protein B BLOC1_2 PF10046.9 KER29603.1 - 0.27 11.6 0.1 0.27 11.6 0.1 5.2 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 KER29603.1 - 4.5 7.6 16.2 2.5 8.4 0.3 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF5082) DUF2570 PF10828.8 KER29604.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SNF2_N PF00176.23 KER29605.1 - 2.1e-57 194.4 0.0 2.7e-40 138.2 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain DUF3535 PF12054.8 KER29605.1 - 1.2e-16 61.0 0.9 1.3e-09 37.8 0.0 4.6 4 1 0 4 4 4 3 Domain of unknown function (DUF3535) Helicase_C PF00271.31 KER29605.1 - 1.1e-07 32.2 0.0 2.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KER29605.1 - 0.00054 20.0 6.4 3.1 8.3 0.0 5.7 5 1 1 6 6 6 2 HEAT repeat ResIII PF04851.15 KER29605.1 - 0.036 14.1 0.0 1.1 9.2 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit GRASP55_65 PF04495.14 KER29608.1 - 7.7e-42 142.9 0.0 5.7e-21 75.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KER29608.1 - 2.2e-05 24.2 0.0 0.002 17.9 0.0 2.5 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 KER29608.1 - 0.001 19.3 0.1 0.0023 18.2 0.0 1.5 2 0 0 2 2 2 1 PDZ domain Pkinase PF00069.25 KER29610.1 - 8.2e-33 113.9 0.0 5.4e-31 107.9 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KER29610.1 - 5.1e-22 78.4 0.1 1.1e-21 77.3 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KER29610.1 - 2.8e-20 72.7 0.0 1.4e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER29610.1 - 0.0041 16.0 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KER29610.1 - 0.0045 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER29610.1 - 0.0083 16.1 0.9 0.068 13.1 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF5323 PF17257.2 KER29610.1 - 0.61 10.0 6.0 0.074 12.9 1.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5323) Tctex-1 PF03645.13 KER29612.1 - 5.3e-26 90.9 0.1 6.5e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF2634 PF10934.8 KER29612.1 - 0.075 13.2 0.8 1.5 9.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2634) IRS PF02174.17 KER29613.1 - 1.7e-08 34.3 0.0 4.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) ThiD2 PF17792.1 KER29614.1 - 0.096 13.2 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 ThiD2 family Brix PF04427.18 KER29615.1 - 2e-27 96.5 0.1 5.8e-26 91.8 0.1 2.2 1 1 0 1 1 1 1 Brix domain Striatin PF08232.12 KER29616.1 - 1e-33 117.2 5.1 1e-33 117.2 5.1 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KER29616.1 - 7.6e-30 102.5 9.4 4e-07 30.6 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER29616.1 - 1.6e-08 34.7 0.0 0.13 12.6 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER29616.1 - 1.2e-05 24.2 0.2 0.86 8.2 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PA14 PF07691.12 KER29616.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 PA14 domain DUF4482 PF14818.6 KER29616.1 - 0.24 12.3 8.8 0.031 15.1 3.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) Pup PF05639.11 KER29616.1 - 0.52 11.3 1.7 2.1 9.3 0.4 2.4 2 0 0 2 2 2 0 Pup-like protein 14-3-3 PF00244.20 KER29617.1 - 2e-96 321.8 0.4 2.5e-96 321.5 0.4 1.1 1 0 0 1 1 1 1 14-3-3 protein MS_channel PF00924.18 KER29617.1 - 0.051 13.1 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel SIKE PF05769.11 KER29617.1 - 0.28 11.1 2.5 0.77 9.7 0.3 2.5 3 0 0 3 3 3 0 SIKE family adh_short PF00106.25 KER29618.1 - 2.2e-37 128.4 0.0 3.2e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER29618.1 - 2.9e-16 59.8 0.0 4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER29618.1 - 1.5e-11 44.5 0.6 4.7e-11 42.9 0.0 2.1 3 0 0 3 3 3 1 KR domain DUF2955 PF11168.8 KER29618.1 - 0.05 13.4 0.9 0.12 12.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Cadherin PF00028.17 KER29619.1 - 2e-09 37.8 0.0 2.3e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 Cadherin domain Adeno_E3_CR2 PF02439.15 KER29619.1 - 0.048 13.4 1.7 0.09 12.6 1.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 KER29620.1 - 1.3e-48 163.4 6.1 1.1e-09 38.6 0.0 9.8 7 2 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 KER29620.1 - 6e-06 26.2 11.1 0.2 11.7 0.1 7.0 8 0 0 8 8 8 2 Cadherin-like Cadherin_2 PF08266.12 KER29620.1 - 0.0003 20.6 0.2 3.5 7.5 0.5 3.8 3 1 0 3 3 3 2 Cadherin-like Cadherin_4 PF17803.1 KER29620.1 - 0.0091 16.6 3.9 4.4 8.0 0.1 3.9 4 0 0 4 4 4 2 Bacterial cadherin-like domain Big_9 PF17963.1 KER29620.1 - 0.08 13.7 6.0 0.47 11.2 0.3 3.6 3 0 0 3 3 3 0 Bacterial Ig domain tRNA-synt_1d PF00750.19 KER29621.1 - 3.3e-132 440.7 0.1 4.1e-132 440.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KER29621.1 - 1.5e-29 102.6 0.0 3.4e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KER29621.1 - 5.8e-20 71.7 0.1 1.3e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 KER29621.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Peripla_BP_6 PF13458.6 KER29621.1 - 0.056 13.1 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein DUF2075 PF09848.9 KER29621.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.22 KER29623.1 - 8.4e-11 41.5 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER29623.1 - 0.019 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_1 PF14446.6 KER29623.1 - 0.99 9.4 6.8 8.6 6.4 5.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FucT_N PF18025.1 KER29624.1 - 0.014 15.9 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain CBM_10 PF02013.16 KER29624.1 - 0.72 10.4 8.7 41 4.8 8.7 2.3 1 1 0 1 1 1 0 Cellulose or protein binding domain WD40 PF00400.32 KER29625.1 - 0.11 13.4 7.9 2 9.4 0.7 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PDCD7 PF16021.5 KER29628.1 - 7.9e-16 58.0 16.0 2.8e-13 49.7 1.3 3.7 2 2 1 3 3 3 2 Programmed cell death protein 7 RRM_1 PF00076.22 KER29630.1 - 1.7e-40 136.7 0.0 1.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER29630.1 - 2.4e-06 27.6 0.0 0.0012 18.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KER29630.1 - 1.1e-05 25.0 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KER29630.1 - 0.21 11.7 0.2 22 5.2 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 KER29630.1 - 0.23 11.7 0.1 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ABC_tran PF00005.27 KER29631.1 - 2.6e-31 109.0 0.0 4.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KER29631.1 - 1.8e-26 93.4 4.2 1.8e-26 93.4 4.2 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KER29631.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RVT_1 PF00078.27 KER29631.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_16 PF13191.6 KER29631.1 - 0.0051 17.2 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER29631.1 - 0.0066 16.7 0.0 0.041 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KER29631.1 - 0.014 15.1 0.1 0.076 12.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 KER29631.1 - 0.045 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 KER29631.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 KER29632.1 - 3.6e-18 65.8 0.0 1e-17 64.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family VHL_C PF17211.3 KER29632.1 - 0.06 13.4 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 VHL box domain Mito_carr PF00153.27 KER29633.1 - 2.2e-11 43.5 0.0 2.6e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Cadherin_3 PF16184.5 KER29635.1 - 1.7e-70 234.1 6.3 5.7e-14 52.1 0.0 14.4 14 1 0 14 14 14 11 Cadherin-like Lectin_C PF00059.21 KER29635.1 - 2.3e-08 34.7 4.4 1.8e-07 31.9 1.1 2.8 2 0 0 2 2 2 1 Lectin C-type domain Calx-beta PF03160.14 KER29635.1 - 3.5e-05 23.9 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 Calx-beta domain Big_9 PF17963.1 KER29635.1 - 0.018 15.8 1.6 97 3.8 0.0 5.4 5 0 0 5 5 5 0 Bacterial Ig domain DHC_N2 PF08393.13 KER29637.1 - 4.2e-48 164.4 2.5 5e-48 164.2 2.5 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 KER29638.1 - 4.5e-149 495.9 0.0 4.4e-148 492.6 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 KER29638.1 - 6.6e-85 284.6 0.0 1.7e-84 283.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER29638.1 - 7.5e-80 268.4 0.0 1.7e-79 267.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER29638.1 - 2e-77 259.3 0.3 2e-77 259.3 0.3 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER29638.1 - 4.3e-69 231.6 0.1 3.7e-63 212.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 KER29638.1 - 8.3e-60 202.6 14.1 1.9e-51 175.2 9.7 2.7 3 0 0 3 3 3 2 Microtubule-binding stalk of dynein motor DHC_N2 PF08393.13 KER29638.1 - 1.1e-54 186.1 11.8 1.7e-41 142.7 1.3 3.4 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_lid_11 PF18198.1 KER29638.1 - 2.1e-49 167.5 0.0 5.8e-49 166.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER29638.1 - 5.6e-41 139.4 0.0 1.4e-38 131.6 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KER29638.1 - 1.1e-21 77.3 0.0 0.00014 21.8 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER29638.1 - 6.2e-21 74.5 0.1 2.7e-20 72.4 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 KER29638.1 - 5.9e-11 42.6 3.7 9.4e-10 38.7 0.4 3.2 2 1 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KER29638.1 - 6.1e-08 33.0 0.1 0.15 12.3 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 KER29638.1 - 5.9e-05 23.5 3.2 0.37 11.2 0.0 4.7 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER29638.1 - 7.3e-05 23.2 6.2 12 6.3 0.0 6.8 6 1 1 7 7 7 0 AAA ATPase domain AAA_19 PF13245.6 KER29638.1 - 0.0065 16.8 0.7 53 4.1 0.0 4.2 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 KER29638.1 - 0.0079 15.3 0.1 0.88 8.6 0.0 2.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 KER29638.1 - 0.02 15.5 0.0 0.34 11.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain Cep57_CLD_2 PF14197.6 KER29638.1 - 0.021 14.9 6.5 0.13 12.4 6.5 2.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AAA_33 PF13671.6 KER29638.1 - 0.04 14.1 0.0 15 5.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain Tup_N PF08581.10 KER29638.1 - 0.097 13.0 9.8 2.4 8.5 3.7 4.3 3 0 0 3 3 3 0 Tup N-terminal AAA_30 PF13604.6 KER29638.1 - 0.5 10.1 8.7 11 5.7 1.2 4.1 4 0 0 4 4 4 0 AAA domain Atg14 PF10186.9 KER29638.1 - 3.3 6.7 9.4 0.56 9.2 0.5 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 KER29638.1 - 6.8 6.4 32.8 9.3 6.0 12.2 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SCAPER_N PF16501.5 KER29642.1 - 0.044 13.8 0.5 5.5 7.1 0.0 2.9 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum Robl_LC7 PF03259.17 KER29645.1 - 0.031 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain 7TM_GPCR_Srw PF10324.9 KER29646.1 - 1.2e-07 31.4 5.2 0.0013 18.1 0.8 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER29646.1 - 0.24 10.7 7.3 3.3 7.0 0.2 3.0 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) RhoGEF PF00621.20 KER29647.1 - 1.4e-23 84.1 2.2 2.6e-22 79.9 1.6 2.5 1 1 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 KER29647.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain MAR_sialic_bdg PF10564.9 KER29651.1 - 0.0001 22.2 0.1 5.4 7.1 0.0 3.4 3 0 0 3 3 3 2 Sialic-acid binding micronemal adhesive repeat SAM_3 PF18016.1 KER29651.1 - 0.00038 20.2 0.1 2.1 8.2 0.0 3.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) YkyB PF14177.6 KER29651.1 - 0.028 14.7 0.4 32 4.8 0.0 3.1 3 0 0 3 3 3 0 YkyB-like protein Poty_coat PF00767.18 KER29651.1 - 0.046 13.3 1.0 1.3 8.5 0.1 2.5 3 0 0 3 3 3 0 Potyvirus coat protein MHB PF16525.5 KER29651.1 - 0.068 13.4 0.1 63 3.9 0.0 3.3 3 0 0 3 3 3 0 Haemophore, haem-binding SAM_1 PF00536.30 KER29651.1 - 0.097 13.1 0.0 19 5.8 0.0 3.1 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Mis12 PF05859.12 KER29651.1 - 0.13 12.3 1.5 54 3.8 0.0 3.2 3 0 0 3 3 3 0 Mis12 protein Sulfotransfer_2 PF03567.14 KER29652.1 - 8.5e-32 111.0 0.0 2.4e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Metallophos PF00149.28 KER29653.1 - 4e-36 125.4 0.2 5.4e-36 125.0 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRIMA1 PF16101.5 KER29654.1 - 0.029 14.4 0.5 0.05 13.6 0.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Laminin_G_2 PF02210.24 KER29654.1 - 0.038 14.6 0.2 0.31 11.6 0.2 2.1 1 1 0 1 1 1 0 Laminin G domain LRR19-TM PF15176.6 KER29654.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Laminin_G_1 PF00054.23 KER29654.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain YccF PF03733.13 KER29654.1 - 0.41 11.4 4.3 0.98 10.2 4.3 1.6 1 0 0 1 1 1 0 Inner membrane component domain Laminin_G_2 PF02210.24 KER29655.1 - 6.1e-15 55.9 0.2 1.1e-07 32.5 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KER29655.1 - 7.1e-08 32.7 0.0 0.00014 22.1 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain DUF4522 PF15022.6 KER29655.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Laminin_G_2 PF02210.24 KER29656.1 - 5.3e-06 27.0 0.1 8e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KER29656.1 - 0.091 13.0 0.0 12 6.1 0.0 2.4 2 1 0 2 2 2 0 Laminin G domain Jnk-SapK_ap_N PF09744.9 KER29657.1 - 6.6e-25 88.2 5.0 6.6e-25 88.2 5.0 3.9 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 RILP PF11461.8 KER29657.1 - 7.1e-08 32.6 2.8 7.1e-08 32.6 2.8 2.3 2 0 0 2 2 2 1 Rab interacting lysosomal protein COMMD1_N PF17221.3 KER29657.1 - 0.053 13.8 2.5 1.1 9.6 0.1 2.9 2 1 1 3 3 3 0 COMMD1 N-terminal domain HEPN_RES_NTD1 PF18870.1 KER29657.1 - 0.19 11.9 1.5 0.37 11.0 1.5 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 APG6_N PF17675.1 KER29657.1 - 4.7 7.7 34.3 7.6 7.1 9.1 3.5 3 0 0 3 3 3 0 Apg6 coiled-coil region EB1 PF03271.17 KER29660.1 - 0.0087 16.3 1.4 0.16 12.3 0.0 2.8 2 1 0 2 2 2 1 EB1-like C-terminal motif SlyX PF04102.12 KER29660.1 - 0.43 11.2 3.3 0.88 10.2 3.3 1.5 1 0 0 1 1 1 0 SlyX Med21 PF11221.8 KER29661.1 - 5.9e-19 68.7 0.6 3.3e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Subunit 21 of Mediator complex CHD5 PF04420.14 KER29661.1 - 1.1e-08 35.1 1.4 5.3e-08 32.9 0.1 2.5 3 0 0 3 3 3 1 CHD5-like protein FUSC PF04632.12 KER29661.1 - 0.0092 14.6 0.7 0.21 10.1 0.0 2.1 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF3421 PF11901.8 KER29662.1 - 1.5e-40 137.7 6.2 3.2e-38 130.3 3.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) HEAT PF02985.22 KER29664.1 - 0.00045 20.2 4.8 0.013 15.7 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KER29664.1 - 0.0052 17.3 0.5 0.13 12.9 0.1 3.5 2 0 0 2 2 2 1 HEAT-like repeat Gly-rich_Ago1 PF12764.7 KER29664.1 - 0.032 15.0 0.9 0.11 13.3 0.9 1.9 1 0 0 1 1 1 0 Glycine-rich region of argonaut HEAT_2 PF13646.6 KER29664.1 - 0.089 13.2 1.0 3.7 8.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Myosin_TH1 PF06017.13 KER29664.1 - 0.23 11.1 0.3 26 4.4 0.0 2.2 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding DGF-1_C PF11040.8 KER29668.1 - 0.05 13.6 0.4 0.087 12.8 0.4 1.7 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RecQ_Zn_bind PF16124.5 KER29670.1 - 0.12 13.1 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 RecQ zinc-binding PX PF00787.24 KER29672.1 - 1.7e-19 69.8 0.3 3.9e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KER29672.1 - 1.3e-09 37.9 12.4 0.00017 21.3 3.5 3.4 2 1 1 3 3 3 3 Vps5 C terminal like Acyl-CoA_dh_2 PF08028.11 KER29672.1 - 0.05 13.9 2.3 0.15 12.3 2.3 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HR1 PF02185.16 KER29672.1 - 0.35 11.0 3.0 0.55 10.4 0.7 2.6 2 1 0 2 2 2 0 Hr1 repeat PA28_beta PF02252.18 KER29673.1 - 1.8e-50 170.4 0.1 3.2e-50 169.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KER29673.1 - 8.1e-06 25.8 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Homeodomain PF00046.29 KER29674.1 - 3.3e-17 62.1 0.6 2e-16 59.6 1.0 2.1 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 KER29674.1 - 5e-09 36.2 5.6 9.5e-09 35.4 5.6 1.4 1 0 0 1 1 1 1 LIM domain Homeobox_KN PF05920.11 KER29674.1 - 0.002 18.0 0.1 0.005 16.7 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-RING_5 PF14634.6 KER29674.1 - 6.3 6.8 9.0 18 5.4 9.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain IFT20 PF14931.6 KER29675.1 - 1.6e-18 67.0 0.1 2.2e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Sec34 PF04136.15 KER29675.1 - 0.087 12.7 0.4 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 Sec34-like family Aminotran_1_2 PF00155.21 KER29676.1 - 6.1e-46 157.2 0.0 9.3e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KER29676.1 - 2.7e-05 23.6 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KER29676.1 - 0.0079 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KER29676.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KER29676.1 - 0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Optomotor-blind PF11078.8 KER29679.1 - 0.039 14.5 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 Optomotor-blind protein N-terminal region Cu_amine_oxid PF01179.20 KER29681.1 - 2.1e-74 250.9 0.0 3.2e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KER29681.1 - 0.0048 16.7 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KER29681.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Sec1 PF00995.23 KER29683.1 - 3.4e-77 261.0 0.0 4.1e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_transf_10 PF00852.19 KER29683.1 - 0.019 14.7 0.2 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Sec1 PF00995.23 KER29684.1 - 1.4e-13 51.0 0.0 1.7e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family PhoLip_ATPase_C PF16212.5 KER29685.1 - 5.4e-48 163.9 28.8 7.6e-45 153.6 19.1 2.2 2 0 0 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KER29685.1 - 1.8e-09 38.2 0.1 8e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER29685.1 - 0.00012 22.1 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KER29685.1 - 0.0048 16.7 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KER29685.1 - 0.037 14.4 0.0 0.28 11.6 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 KER29686.1 - 6e-27 95.0 11.9 2.8e-26 92.8 10.6 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KER29686.1 - 2.2e-09 37.9 0.2 1.8e-06 28.4 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER29686.1 - 1.2e-07 31.7 0.0 2.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KER29686.1 - 0.0032 17.3 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cep57_CLD_2 PF14197.6 KER29686.1 - 0.058 13.5 1.2 0.12 12.5 1.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF5555 PF17710.1 KER29686.1 - 0.076 12.5 0.2 0.64 9.5 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5555) HAD PF12710.7 KER29686.1 - 0.094 13.1 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rsd_AlgQ PF04353.13 KER29688.1 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Act-Frag_cataly PF09192.10 KER29688.1 - 0.02 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF327 PF03885.13 KER29688.1 - 0.038 14.0 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF1967 PF09269.11 KER29688.1 - 0.099 12.6 0.0 0.3 11.1 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) Radical_SAM_C PF16199.5 KER29691.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Cyclin_C PF02984.19 KER29692.1 - 0.00016 21.7 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KER29692.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain Glypican PF01153.19 KER29694.1 - 2.3e-21 76.3 7.9 2.5e-20 72.9 2.9 3.0 2 1 0 2 2 2 2 Glypican CENP-B_dimeris PF09026.10 KER29694.1 - 0.027 14.9 9.5 0.065 13.6 9.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KER29694.1 - 2.6 7.3 10.2 5.2 6.3 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KER29694.1 - 2.8 7.6 10.4 5.6 6.6 10.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein I-set PF07679.16 KER29695.1 - 4.3e-34 116.4 0.0 6.7e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KER29695.1 - 1.1e-23 83.6 0.0 2.5e-09 37.6 0.0 4.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KER29695.1 - 1.4e-14 54.1 0.1 3.4e-06 27.3 0.1 3.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 KER29695.1 - 5.7e-10 39.2 0.1 1.1e-05 25.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain BiPBP_C PF06832.12 KER29695.1 - 1e-07 31.9 0.0 0.021 14.8 0.0 4.3 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 KER29695.1 - 5.4e-05 23.2 0.0 0.12 12.5 0.0 3.5 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KER29695.1 - 0.002 18.3 6.2 2 8.7 0.6 4.6 4 1 0 4 4 4 2 Immunoglobulin V-set domain C1-set PF07654.15 KER29695.1 - 0.017 15.5 0.8 2.5 8.5 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin C1-set domain Kinesin PF00225.23 KER29696.1 - 1.6e-52 178.5 0.2 4.9e-30 104.6 0.0 3.8 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KER29696.1 - 1e-16 61.2 1.3 4.1e-11 43.0 0.1 4.0 2 1 1 3 3 3 3 Microtubule binding DUF1192 PF06698.11 KER29696.1 - 0.93 9.6 3.2 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ribosomal_L23 PF00276.20 KER29697.1 - 5.6e-17 61.9 3.5 5.6e-17 61.9 3.5 2.9 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 KER29697.1 - 2.8e-10 40.3 8.3 2.8e-10 40.3 8.3 3.3 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain DUF4467 PF14729.6 KER29700.1 - 0.05 14.0 0.5 0.05 14.0 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Cytochrome_cB PF11783.8 KER29700.1 - 0.069 13.0 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c bacterial RVT_1 PF00078.27 KER29702.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KER29702.1 - 3.2e-06 27.3 13.6 0.0012 19.2 1.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER29702.1 - 2.8e-05 24.6 18.3 0.12 13.3 0.1 4.0 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KER29702.1 - 0.00065 20.0 14.6 0.0092 16.4 0.1 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KER29702.1 - 0.0019 17.9 1.9 0.018 14.8 0.2 3.0 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-CCHC_5 PF14787.6 KER29702.1 - 0.21 11.4 2.8 13 5.6 0.2 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C2H2_2 PF12756.7 KER29702.1 - 0.28 11.6 6.4 0.41 11.0 2.1 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KER29702.1 - 0.69 9.6 10.2 3.2 7.4 0.6 4.2 3 1 1 4 4 4 0 MYST family zinc finger domain ADK_lid PF05191.14 KER29702.1 - 0.87 9.6 5.2 14 5.7 1.0 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 KER29702.1 - 1.8 8.6 7.6 0.9 9.5 0.9 3.2 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KER29702.1 - 4.3 7.0 6.9 8.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 KER29702.1 - 5 7.5 9.6 5.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RT_RNaseH_2 PF17919.1 KER29707.1 - 5.4e-11 42.4 0.1 9.9e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER29707.1 - 7.6e-09 35.8 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KER29710.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER29710.1 - 0.042 14.5 0.0 0.075 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2_2 PF13465.6 KER29714.1 - 6.4e-08 32.7 9.3 1.6e-05 25.1 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER29714.1 - 1.5e-05 25.5 9.1 0.0012 19.5 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KER29714.1 - 0.00085 19.6 8.5 0.0024 18.2 1.9 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KER29714.1 - 0.025 14.6 6.2 0.051 13.6 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.18 KER29714.1 - 0.14 12.0 1.9 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) C5HCH PF17982.1 KER29714.1 - 1.6 9.0 5.1 0.7 10.1 0.4 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-H2C2_2 PF13465.6 KER29715.1 - 1.8e-13 50.2 18.3 1.1e-06 28.8 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KER29715.1 - 1.8e-12 47.0 25.4 6.8e-05 23.1 4.1 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER29715.1 - 6.4e-11 42.1 25.4 0.0049 17.6 4.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER29715.1 - 8.1e-09 35.6 11.6 0.27 11.6 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER29715.1 - 1.5e-07 31.3 24.9 0.0076 16.2 2.8 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-MYST PF17772.1 KER29715.1 - 1.3e-05 24.7 15.2 0.22 11.2 0.5 4.6 2 2 2 4 4 4 4 MYST family zinc finger domain zf-C2H2_8 PF15909.5 KER29715.1 - 0.0013 19.0 12.5 0.062 13.6 0.9 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon GAGA PF09237.11 KER29715.1 - 0.0013 18.4 8.0 0.097 12.5 0.4 3.3 2 1 1 3 3 3 1 GAGA factor zf-C2H2_2 PF12756.7 KER29715.1 - 0.0037 17.6 13.9 1.2 9.5 1.9 4.1 1 1 3 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KER29715.1 - 0.0038 17.6 12.8 0.89 10.0 1.7 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KER29715.1 - 0.0095 15.8 1.1 0.0095 15.8 1.1 3.6 4 0 0 4 4 3 1 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 KER29715.1 - 0.027 15.2 8.4 0.11 13.3 0.7 2.8 2 1 0 2 2 2 0 zinc-ribbon family SEN1_N PF12726.7 KER29715.1 - 0.04 12.1 0.6 0.057 11.6 0.6 1.2 1 0 0 1 1 1 0 SEN1 N terminal Desulfoferrod_N PF06397.12 KER29715.1 - 0.079 12.6 3.5 5 6.8 0.4 3.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF3268 PF11672.8 KER29715.1 - 0.12 12.7 4.8 0.28 11.5 1.4 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zinc_ribbon_5 PF13719.6 KER29715.1 - 0.22 11.3 6.6 9.9 6.0 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Baculo_IE-1 PF05290.11 KER29715.1 - 0.24 11.3 4.8 12 5.8 0.1 3.1 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_9 PF16293.5 KER29715.1 - 0.25 11.2 3.7 8.8 6.3 0.2 2.6 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 KER29715.1 - 0.41 9.8 3.7 6.4 5.9 0.1 2.4 2 1 0 2 2 2 0 Putative actin-like family zf-C2HE PF16278.5 KER29715.1 - 0.64 10.5 17.7 0.15 12.6 2.1 4.1 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 KER29715.1 - 0.78 9.4 10.1 4.2 7.1 0.6 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PyrI_C PF02748.15 KER29715.1 - 0.89 9.5 8.1 2.9 7.9 0.1 3.3 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 KER29715.1 - 1.3 9.2 9.7 56 4.0 0.1 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger FOXP-CC PF16159.5 KER29715.1 - 1.4 9.6 6.7 8.1 7.2 0.7 3.0 3 0 0 3 3 2 0 FOXP coiled-coil domain zf-U1 PF06220.12 KER29715.1 - 1.7 8.5 9.9 0.56 10.0 0.5 2.9 3 0 0 3 3 2 0 U1 zinc finger Zn-ribbon_8 PF09723.10 KER29715.1 - 2 8.6 12.1 50 4.1 0.7 4.3 4 0 0 4 4 4 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 KER29715.1 - 2.4 8.7 7.4 8.9 6.9 3.0 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain C1_1 PF00130.22 KER29715.1 - 2.5 8.0 10.9 2.5 8.0 1.2 3.4 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.12 KER29715.1 - 2.7 8.3 15.1 19 5.6 3.8 3.9 2 2 2 4 4 4 0 TFIIH C1-like domain DZR PF12773.7 KER29715.1 - 3.2 7.8 13.6 0.51 10.4 2.5 3.0 2 2 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KER29716.1 - 0.00026 21.5 20.0 0.034 15.0 3.6 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KER29716.1 - 0.00029 21.1 21.0 0.054 14.0 4.2 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER29716.1 - 0.0047 17.3 18.5 0.072 13.5 2.6 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KER29716.1 - 0.035 14.4 3.3 0.035 14.4 3.3 2.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KER29716.1 - 0.046 13.8 5.4 2.1 8.5 5.8 3.0 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KER29716.1 - 0.2 11.6 8.2 0.088 12.7 3.7 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-HIT PF04438.16 KER29716.1 - 0.67 9.9 7.8 2.6 8.0 0.5 3.2 3 0 0 3 3 3 0 HIT zinc finger CpXC PF14353.6 KER29716.1 - 1.6 8.8 5.1 33 4.6 2.3 3.1 1 1 2 3 3 3 0 CpXC protein C1_4 PF07975.12 KER29716.1 - 3.8 7.8 12.0 1.3 9.3 0.8 3.4 2 1 1 3 3 3 0 TFIIH C1-like domain Ank_2 PF12796.7 KER29719.1 - 9.9e-18 64.5 0.0 1.1e-06 29.1 0.0 4.4 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KER29719.1 - 1.3e-16 60.2 7.9 8.4e-06 26.0 0.0 7.3 6 1 1 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KER29719.1 - 5.7e-14 52.3 0.7 0.033 14.8 0.0 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER29719.1 - 3e-13 48.6 3.9 0.07 13.7 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat MORN PF02493.20 KER29719.1 - 8.1e-12 44.3 17.7 0.0018 18.0 0.3 6.4 6 0 0 6 6 6 4 MORN repeat zf-MYND PF01753.18 KER29719.1 - 6.2e-05 23.0 8.8 0.00014 21.9 8.8 1.6 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 KER29719.1 - 0.00076 19.7 4.1 1.5 9.3 0.3 4.9 4 1 0 4 4 4 2 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 KER29720.1 - 4.2e-08 33.5 0.0 0.0011 19.3 0.0 4.4 3 1 2 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 KER29720.1 - 7e-07 28.7 0.2 2.8 8.1 0.0 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KER29720.1 - 0.0016 17.9 0.0 8.4 6.2 0.0 4.0 4 0 0 4 4 4 2 EF hand FANCI_HD2 PF14680.6 KER29720.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 Plexin_cytopl PF08337.12 KER29720.1 - 0.13 11.0 0.0 0.89 8.1 0.0 2.0 1 1 0 1 1 1 0 Plexin cytoplasmic RasGAP domain SIT PF15330.6 KER29721.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT NicO PF03824.16 KER29722.1 - 0.56 9.5 14.9 0.94 8.8 14.9 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2946 PF11162.8 KER29722.1 - 6.4 7.5 13.7 15 6.3 13.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3110 PF11360.8 KER29724.1 - 0.13 12.5 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) NT-C2 PF10358.9 KER29725.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CLIP_SPH_Scar PF18399.1 KER29727.1 - 0.049 13.7 0.0 6.2 7.0 0.0 2.3 1 1 1 2 2 2 0 Clip-domain serine protease homolog Scarface Tmemb_9 PF05434.11 KER29728.1 - 3e-34 118.0 0.1 1.1e-24 87.0 0.1 2.4 2 0 0 2 2 2 2 TMEM9 Gemini_mov PF01708.16 KER29728.1 - 0.039 13.7 0.3 0.096 12.5 0.3 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein AMP-binding PF00501.28 KER29729.1 - 2.7e-82 276.6 0.0 2.4e-40 138.5 0.0 2.9 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KER29729.1 - 0.035 15.1 0.2 0.17 12.9 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF3203 PF11462.8 KER29731.1 - 0.13 12.5 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) BAH PF01426.18 KER29732.1 - 3.9e-27 94.5 0.4 3e-26 91.7 0.1 2.4 2 1 0 2 2 2 1 BAH domain ELM2 PF01448.24 KER29732.1 - 2.7e-07 31.2 0.0 7.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain GATA PF00320.27 KER29732.1 - 2.7e-05 23.7 5.6 5.5e-05 22.7 5.6 1.6 1 0 0 1 1 1 1 GATA zinc finger MTA_R1 PF17226.2 KER29732.1 - 0.0011 19.1 0.9 0.0029 17.7 0.9 1.7 1 0 0 1 1 1 1 MTA R1 domain Myb_DNA-binding PF00249.31 KER29732.1 - 0.15 12.3 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TMEM119 PF15724.5 KER29732.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 TMEM119 family DNA_pol_phi PF04931.13 KER29736.1 - 0.0022 16.2 20.8 0.0028 15.9 20.8 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF2722 PF10846.8 KER29736.1 - 0.012 14.5 4.8 0.015 14.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFB6 PF17110.5 KER29736.1 - 0.019 14.7 2.1 0.026 14.3 2.1 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Cwf_Cwc_15 PF04889.12 KER29736.1 - 0.019 14.7 20.0 0.031 14.0 20.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KER29736.1 - 0.026 14.4 5.4 0.032 14.1 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 KER29736.1 - 0.36 10.2 9.0 0.46 9.8 9.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 KER29736.1 - 0.37 10.1 8.0 0.44 9.8 8.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KER29736.1 - 0.4 10.1 11.5 0.45 9.9 11.5 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 KER29736.1 - 0.77 8.9 6.4 1.4 8.1 6.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 KER29736.1 - 1.1 7.3 5.1 1.4 6.9 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CNDH2_C PF16858.5 KER29736.1 - 1.2 9.0 4.7 1.5 8.7 4.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PPP4R2 PF09184.11 KER29736.1 - 1.3 8.5 11.4 1.7 8.2 11.4 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 KER29736.1 - 1.8 6.8 12.0 2.5 6.3 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER29736.1 - 2.1 6.4 15.6 2.9 6.0 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family Osteopontin PF00865.18 KER29736.1 - 2.2 7.7 25.5 2.8 7.4 25.5 1.1 1 0 0 1 1 1 0 Osteopontin SGT1 PF07093.11 KER29736.1 - 3 6.2 6.1 3.5 6.0 6.1 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.11 KER29736.1 - 3.7 6.0 13.2 4.7 5.6 13.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 KER29736.1 - 4.5 6.3 31.5 6 5.9 31.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 KER29736.1 - 5.1 5.5 9.4 6.7 5.2 9.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2076 PF09849.9 KER29736.1 - 5.4 7.0 16.3 7.1 6.6 16.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4483 PF14825.6 KER29737.1 - 3.7e-33 114.5 0.1 5.4e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Coatomer_g_Cpla PF16381.5 KER29737.1 - 0.098 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform BPL_N PF09825.9 KER29739.1 - 5.9e-06 25.6 0.0 6.8e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal NinD PF17466.2 KER29742.1 - 6.2 7.0 9.3 13 5.9 0.2 3.0 2 1 1 3 3 3 0 Family of unknown function Synaptobrevin PF00957.21 KER29744.1 - 1.8e-10 40.5 0.4 3e-10 39.7 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin MAM1 PF10434.9 KER29744.1 - 0.13 11.9 0.6 1.8 8.1 0.0 1.9 1 1 0 2 2 2 0 Monopolin complex protein MAM1 zf_CCCH_4 PF18345.1 KER29745.1 - 6.8e-05 22.8 10.3 0.0029 17.6 1.1 3.8 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KER29745.1 - 0.0002 21.2 16.2 0.013 15.4 1.1 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KER29745.1 - 0.014 16.1 9.3 0.21 12.3 0.6 2.8 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KER29745.1 - 0.062 13.5 4.7 0.16 12.2 4.7 1.7 1 0 0 1 1 1 0 Zinc-finger containing family zf-C3H1 PF10650.9 KER29745.1 - 0.11 12.3 5.4 0.54 10.0 2.4 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain Regulator_TrmB PF11495.8 KER29746.1 - 0.16 11.1 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF2674 PF10879.8 KER29748.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Glyco_hydro_130 PF04041.13 KER29753.1 - 0.042 12.8 0.1 0.072 12.0 0.1 1.3 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase DUF3763 PF12592.8 KER29753.1 - 1.2 9.3 5.3 6.7 6.9 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) bZIP_1 PF00170.21 KER29754.1 - 2.6e-13 49.9 7.2 5.2e-13 48.9 7.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KER29754.1 - 2.3e-07 30.8 8.4 4.5e-07 29.9 8.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KER29754.1 - 0.00028 21.3 9.1 0.00028 21.3 9.1 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Peptidase_C58 PF03543.14 KER29757.1 - 0.088 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Guanylate_kin PF00625.21 KER29759.1 - 1.8e-39 135.3 0.0 2.9e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 KER29759.1 - 1.7e-05 24.4 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER29759.1 - 3e-05 23.5 0.1 7.4e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER29759.1 - 0.0091 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5464 PF17552.2 KER29761.1 - 0.19 12.0 0.7 0.31 11.3 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5464) Linker_histone PF00538.19 KER29763.1 - 2.2e-24 85.6 0.2 2.9e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 linker histone H1 and H5 family ASC PF00858.24 KER29765.1 - 4.2e-12 45.8 4.5 7.4e-11 41.7 3.3 2.3 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel DUF1754 PF08555.10 KER29767.1 - 1.8 9.4 9.4 3.7e+03 -1.2 9.4 7.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM60A PF15396.6 KER29767.1 - 2.4 8.1 5.1 5e+02 0.5 5.1 5.4 1 0 0 1 1 1 0 Protein Family FAM60A Aida_C2 PF14186.6 KER29768.1 - 2.1e-18 66.4 146.6 11 5.7 0.2 28.9 29 0 0 29 29 29 28 Cytoskeletal adhesion Benyvirus_14KDa PF07255.11 KER29768.1 - 0.018 15.3 156.0 57 4.0 0.3 29.1 29 0 0 29 29 29 0 Benyvirus 14KDa protein EF-hand_8 PF13833.6 KER29768.1 - 0.054 13.3 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Abhydrolase_1 PF00561.20 KER29769.1 - 4e-22 79.1 0.1 2.2e-21 76.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER29769.1 - 4.4e-19 70.0 0.0 5.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KER29769.1 - 1.2e-09 37.8 0.1 1.9e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KER29769.1 - 1.8e-08 34.4 0.0 0.00012 21.9 0.0 2.8 2 1 1 3 3 3 2 PGAP1-like protein Thioesterase PF00975.20 KER29769.1 - 5.2e-08 33.3 0.0 1.1e-07 32.3 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 KER29769.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 KER29769.1 - 0.00039 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.14 KER29769.1 - 0.00061 18.6 0.0 0.0033 16.2 0.0 1.8 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KER29769.1 - 0.0013 18.5 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KER29769.1 - 0.008 15.8 0.0 0.093 12.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KER29769.1 - 0.0094 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KER29769.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 KER29769.1 - 0.027 14.3 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KER29769.1 - 0.031 12.8 0.0 0.14 10.7 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Palm_thioest PF02089.15 KER29769.1 - 0.031 14.1 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase PF00151.19 KER29769.1 - 0.037 13.3 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Lipase Peptidase_S9 PF00326.21 KER29769.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family LCAT PF02450.15 KER29769.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Tachykinin PF02202.16 KER29770.1 - 0.32 11.0 1.1 1.1 9.3 1.1 2.1 1 0 0 1 1 1 0 Tachykinin family Cyclin_C_2 PF16899.5 KER29772.1 - 4.4e-06 27.0 0.0 8.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KER29772.1 - 9.9e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain AA_permease PF00324.21 KER29773.1 - 9.5e-50 169.6 23.5 1.7e-49 168.7 23.5 1.4 1 0 0 1 1 1 1 Amino acid permease Zip PF02535.22 KER29774.1 - 6.3e-36 124.2 7.6 9.6e-24 84.2 8.6 2.4 1 1 0 2 2 2 2 ZIP Zinc transporter EST1 PF10374.9 KER29776.1 - 2e-34 119.1 0.1 7.7e-34 117.3 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 KER29776.1 - 9.2e-17 61.4 1.3 1.7e-16 60.5 1.3 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Forkhead PF00250.18 KER29776.1 - 0.0047 17.1 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Forkhead domain zf-CHCC PF10276.9 KER29778.1 - 6.7e-10 38.9 0.2 1.3e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain Thiolase_C PF02803.18 KER29778.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Thiolase, C-terminal domain GST_C_3 PF14497.6 KER29779.1 - 4.2e-16 59.0 0.0 6.3e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER29779.1 - 2.1e-08 34.3 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER29779.1 - 3.7e-05 23.7 0.0 7.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER29779.1 - 5e-05 23.6 0.0 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KER29779.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER29779.1 - 0.038 14.3 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TNFR_c6 PF00020.18 KER29781.1 - 0.017 15.5 1.5 0.028 14.8 1.5 1.3 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region RNA_pol_N PF01194.17 KER29781.1 - 0.056 13.7 0.5 0.09 13.1 0.5 1.3 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit DUF4635 PF15466.6 KER29784.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) fn3 PF00041.21 KER29785.1 - 3.6e-71 235.5 17.2 2.2e-10 40.7 0.0 14.1 12 4 0 12 12 12 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER29785.1 - 1.9e-28 98.8 5.2 0.00064 20.3 0.1 10.1 9 1 0 9 9 9 7 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 KER29785.1 - 6.6e-07 29.6 0.1 11 6.5 0.0 5.9 5 0 0 5 5 5 3 Uncharacterised conserved protein (DUF2369) SAM_1 PF00536.30 KER29786.1 - 2.8e-08 34.1 0.0 4.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER29786.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LMP PF04778.12 KER29786.1 - 0.46 10.4 1.3 16 5.4 0.2 2.3 2 0 0 2 2 2 0 LMP repeated region AAA PF00004.29 KER29787.1 - 2.2e-14 54.0 0.0 4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KER29787.1 - 2.1e-10 40.6 0.0 1.5e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 KER29787.1 - 6e-06 26.7 0.0 3.6e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KER29787.1 - 2.7e-05 24.4 0.1 5.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 KER29787.1 - 4.3e-05 23.3 0.0 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KER29787.1 - 0.00019 20.9 0.0 0.00078 18.9 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KER29787.1 - 0.00026 20.8 0.0 0.00067 19.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KER29787.1 - 0.00034 20.5 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER29787.1 - 0.00036 20.8 0.1 0.014 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER29787.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 KER29787.1 - 0.0016 18.4 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.6 KER29787.1 - 0.0017 18.4 0.0 0.014 15.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KER29787.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KER29787.1 - 0.013 15.9 0.0 0.046 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KER29787.1 - 0.023 14.7 0.1 0.098 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1940 PF09155.10 KER29787.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) ResIII PF04851.15 KER29787.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KER29787.1 - 0.035 14.3 0.1 0.1 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KER29787.1 - 0.036 13.8 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KER29787.1 - 0.05 13.2 0.0 0.24 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KER29787.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 KER29787.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain TIP49 PF06068.13 KER29787.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain DNA_pol3_delta PF06144.13 KER29787.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 KER29787.1 - 0.19 12.1 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CBFD_NFYB_HMF PF00808.23 KER29788.1 - 2.4e-13 50.2 0.7 4.7e-13 49.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER29788.1 - 1.3e-07 32.0 1.5 1.6e-07 31.8 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 KER29788.1 - 0.00045 20.4 0.1 0.00081 19.6 0.1 1.3 1 0 0 1 1 1 1 CENP-W protein Bromo_TP PF07524.13 KER29788.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 KER29788.1 - 0.11 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Phosphorylase PF00343.20 KER29789.1 - 0 1097.2 0.0 0 1096.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase bZIP_2 PF07716.15 KER29790.1 - 2.6e-11 43.4 10.6 4.4e-11 42.7 10.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KER29790.1 - 0.0016 18.5 5.9 0.0028 17.7 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor ETF PF01012.21 KER29791.1 - 2.6e-44 151.3 0.8 3.5e-44 150.9 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HARE-HTH PF05066.13 KER29791.1 - 0.018 15.4 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain RVT_1 PF00078.27 KER29792.1 - 1e-24 87.3 0.0 2.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.31 KER29792.1 - 3.2e-24 84.8 1.0 5.8e-24 84.0 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 KER29792.1 - 7.4e-07 29.1 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KER29792.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Cupin_4 PF08007.12 KER29794.1 - 1.2e-58 199.2 2.1 5.2e-58 197.0 0.0 2.4 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 KER29794.1 - 4e-10 39.8 1.5 3.1e-07 30.4 0.0 3.3 2 1 0 2 2 2 1 Cupin-like domain Cupin_1 PF00190.22 KER29794.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KER29794.1 - 0.0062 16.2 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Cupin domain SPG4 PF17325.2 KER29794.1 - 8.5 7.5 11.3 1.7 9.8 6.4 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 adh_short PF00106.25 KER29797.1 - 5e-47 159.9 0.6 9e-18 64.4 0.0 4.9 1 1 2 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KER29797.1 - 3.2e-29 102.2 0.0 4.6e-11 42.7 0.0 4.5 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KER29797.1 - 2.4e-08 33.7 0.1 0.00069 19.2 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KER29797.1 - 4e-06 26.9 0.0 0.00085 19.3 0.0 2.5 2 1 0 2 2 2 1 KR domain Baculo_LEF-11 PF06385.12 KER29797.1 - 1.5e-05 25.4 0.6 0.17 12.4 0.0 2.6 2 0 0 2 2 2 2 Baculovirus LEF-11 protein Rsbr_N PF08678.10 KER29797.1 - 0.00089 19.3 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 Rsbr N terminal DGCR6 PF07324.11 KER29797.1 - 0.014 15.0 0.0 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein NusB PF01029.18 KER29797.1 - 0.12 12.6 0.1 19 5.5 0.1 2.4 2 0 0 2 2 2 0 NusB family PHF12_MRG_bd PF16737.5 KER29797.1 - 0.14 11.9 0.0 26 4.7 0.0 2.4 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain tRNA_synthFbeta PF17759.1 KER29798.1 - 4.4e-33 114.5 0.0 1.2e-22 80.4 0.0 2.6 2 1 1 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KER29798.1 - 5.6e-26 90.6 0.1 2.6e-25 88.4 0.1 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KER29798.1 - 9.2e-22 77.5 0.0 2.2e-21 76.3 0.0 1.7 1 1 0 1 1 1 1 B3/4 domain B5 PF03484.15 KER29798.1 - 1.9e-12 47.3 0.0 1.6e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain CRIM PF16978.5 KER29799.1 - 3e-15 56.6 0.0 7.4e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain LRR19-TM PF15176.6 KER29800.1 - 0.036 14.1 0.9 0.036 14.1 0.9 2.5 2 1 2 4 4 4 0 Leucine-rich repeat family 19 TM domain TssN PF17555.2 KER29800.1 - 4.8 6.5 10.1 7.2 5.9 10.1 1.3 1 1 0 1 1 1 0 Type VI secretion system, TssN DNA_ligase_A_M PF01068.21 KER29801.1 - 2.3e-50 171.1 0.0 4.5e-41 140.7 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KER29801.1 - 9.4e-31 107.4 1.7 1.6e-30 106.7 0.9 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KER29801.1 - 1.4e-17 64.1 0.0 3.3e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KER29801.1 - 2.5e-06 27.9 0.0 4.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KER29801.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain 7tm_1 PF00001.21 KER29802.1 - 1.9e-11 43.8 11.0 1.9e-11 43.8 11.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4477 PF14780.6 KER29803.1 - 2.7e-07 30.4 4.2 2.7e-07 30.4 4.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) Sec1 PF00995.23 KER29804.1 - 5e-94 316.6 0.0 5.8e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA_6 PF12774.7 KER29805.1 - 5.5e-121 403.5 2.4 1.5e-116 388.9 0.0 4.9 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER29805.1 - 1.9e-113 379.6 15.2 1.9e-113 379.6 15.2 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KER29805.1 - 9e-68 228.4 0.0 3.7e-67 226.4 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 KER29805.1 - 8.5e-58 196.4 0.4 8.5e-58 196.4 0.4 7.0 6 2 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 KER29805.1 - 2.3e-46 157.6 0.1 9.1e-40 136.1 0.0 5.2 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_5 PF07728.14 KER29805.1 - 3.9e-30 104.7 0.0 1.2e-12 48.0 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KER29805.1 - 6.8e-20 71.5 0.0 2.1e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KER29805.1 - 2.1e-14 53.9 8.4 0.029 14.6 0.0 7.2 7 0 0 7 7 7 4 AAA domain AAA PF00004.29 KER29805.1 - 1.2e-13 51.6 0.0 0.0084 16.5 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) MT PF12777.7 KER29805.1 - 4.3e-12 45.7 3.3 8.4e-12 44.8 3.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 KER29805.1 - 2.9e-11 44.1 1.3 1.4 9.3 0.0 7.7 7 0 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 KER29805.1 - 8.6e-11 42.2 0.2 0.042 14.0 0.0 6.0 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 KER29805.1 - 2.2e-09 37.9 0.1 0.39 11.3 0.0 5.9 5 0 0 5 5 5 2 AAA domain Mg_chelatase PF01078.21 KER29805.1 - 2.5e-06 27.0 3.9 0.055 12.8 0.0 4.0 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KER29805.1 - 2.5e-05 23.5 0.0 0.056 12.5 0.0 3.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KER29805.1 - 8.3e-05 22.7 0.0 0.00042 20.5 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_29 PF13555.6 KER29805.1 - 0.00012 21.7 0.0 2.4 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KER29805.1 - 0.00041 20.1 2.4 23 4.6 0.0 5.2 5 0 0 5 5 5 0 AAA domain AAA_30 PF13604.6 KER29805.1 - 0.00052 19.8 5.2 5.9 6.6 0.0 4.8 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 KER29805.1 - 0.001 19.4 0.0 3 8.3 0.0 4.3 4 0 0 4 4 4 1 RNA helicase FtsK_SpoIIIE PF01580.18 KER29805.1 - 0.0013 18.1 0.0 6.7 6.0 0.0 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Rad17 PF03215.15 KER29805.1 - 0.0016 18.4 0.0 22 4.9 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_25 PF13481.6 KER29805.1 - 0.0033 17.0 0.1 0.45 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KER29805.1 - 0.0069 16.9 7.9 3.8 8.0 0.0 5.5 5 0 0 5 5 3 1 ABC transporter AAA_19 PF13245.6 KER29805.1 - 0.014 15.7 7.4 0.14 12.5 0.0 5.2 5 0 0 5 5 5 0 AAA domain NACHT PF05729.12 KER29805.1 - 0.18 11.7 4.3 27 4.6 0.0 4.7 5 0 0 5 5 4 0 NACHT domain DUF1182 PF06681.13 KER29805.1 - 0.46 10.1 3.3 16 5.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) IstB_IS21 PF01695.17 KER29805.1 - 0.83 9.4 11.1 1.6 8.4 0.0 5.2 6 0 0 6 6 6 0 IstB-like ATP binding protein DUF2205 PF10224.9 KER29805.1 - 2.9 8.0 10.8 10 6.2 4.9 3.6 2 1 1 3 3 3 0 Short coiled-coil protein SNF PF00209.18 KER29810.1 - 8.4e-207 688.0 38.1 1e-206 687.7 38.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family zf-RING_UBOX PF13445.6 KER29811.1 - 5.2e-08 32.8 7.9 5.2e-08 32.8 7.9 3.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KER29811.1 - 1.7e-07 31.0 4.8 1.7e-07 31.0 4.8 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER29811.1 - 9e-06 25.5 11.5 9e-06 25.5 11.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER29811.1 - 0.00061 19.6 18.5 0.0055 16.5 13.6 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KER29811.1 - 0.0035 17.5 12.8 0.0035 17.5 12.8 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KER29811.1 - 0.014 15.7 18.0 0.014 15.7 18.0 3.4 3 1 0 3 3 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 KER29811.1 - 0.019 14.8 13.8 0.019 14.8 13.8 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER29811.1 - 0.026 14.5 13.1 0.026 14.5 13.1 3.8 3 1 0 3 3 3 0 zinc-RING finger domain U-box PF04564.15 KER29811.1 - 0.045 13.9 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 U-box domain OrfB_Zn_ribbon PF07282.11 KER29811.1 - 0.39 10.7 0.1 0.39 10.7 0.1 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DUF4796 PF16044.5 KER29811.1 - 0.76 9.3 6.2 1.7 8.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) zf-RING_6 PF14835.6 KER29811.1 - 1.6 8.7 17.5 0.28 11.1 6.4 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf_UBZ PF18439.1 KER29811.1 - 1.8 8.2 10.0 1.9 8.2 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Sec10 PF07393.11 KER29812.1 - 0.0029 16.1 0.2 0.0036 15.8 0.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 V-ATPase_C PF03223.15 KER29812.1 - 0.067 12.6 0.1 0.16 11.4 0.1 1.5 1 1 1 2 2 2 0 V-ATPase subunit C WD40 PF00400.32 KER29816.1 - 8.3e-22 77.1 4.8 1.8e-07 31.7 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER29816.1 - 9.5e-05 22.6 0.0 0.97 9.8 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER29816.1 - 0.2 10.6 0.0 5.7 5.8 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KER29817.1 - 3e-18 65.8 8.1 7.2e-06 26.7 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER29817.1 - 1.2e-06 28.7 0.1 0.0039 17.5 0.0 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER29817.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KER29817.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain Caps_synth PF05704.12 KER29819.1 - 0.1 12.0 4.6 0.06 12.7 2.1 1.5 1 1 1 2 2 2 0 Capsular polysaccharide synthesis protein rve PF00665.26 KER29820.1 - 1.4e-15 57.5 0.0 1.5e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 Integrase core domain rve_3 PF13683.6 KER29820.1 - 0.015 15.1 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Bromodomain PF00439.25 KER29821.1 - 8e-74 243.8 4.5 1.4e-18 66.8 0.1 5.0 4 0 0 4 4 4 4 Bromodomain BET PF17035.5 KER29821.1 - 1.4e-53 178.9 6.1 1.3e-26 92.6 0.2 2.7 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation Sec3_C_2 PF15278.6 KER29821.1 - 0.00016 21.9 2.5 0.19 12.1 0.2 3.1 2 0 0 2 2 2 2 Sec3 exocyst complex subunit Dna2 PF08696.11 KER29821.1 - 0.019 14.8 9.3 0.34 10.7 0.1 3.2 4 0 0 4 4 4 0 DNA replication factor Dna2 DUF16 PF01519.16 KER29821.1 - 0.049 14.1 1.4 11 6.6 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF424 PF04242.13 KER29821.1 - 0.11 12.8 0.0 24 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF424) LXG PF04740.12 KER29821.1 - 0.21 11.3 3.6 1.6 8.4 0.4 2.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 KER29821.1 - 0.5 10.4 2.9 30 4.7 0.7 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 KER29821.1 - 1.7 9.3 19.5 1.2 9.8 0.7 4.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Kinesin PF00225.23 KER29823.1 - 1.1e-71 241.5 0.0 2.5e-57 194.3 0.0 2.8 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KER29823.1 - 2.6e-07 30.7 0.4 9.9e-06 25.6 0.1 3.0 1 1 1 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 KER29823.1 - 0.00052 20.2 0.4 0.0022 18.2 0.4 2.2 1 1 0 1 1 1 1 Kinesin-associated betaPIX_CC PF16523.5 KER29823.1 - 0.021 14.7 2.1 0.046 13.6 2.1 1.6 1 0 0 1 1 1 0 betaPIX coiled coil DUF4164 PF13747.6 KER29823.1 - 0.57 10.5 4.8 0.12 12.7 0.5 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) HIP1_clath_bdg PF16515.5 KER29823.1 - 1.1 9.9 4.9 1.5 9.5 0.4 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MFS_1 PF07690.16 KER29824.1 - 6.2e-42 143.8 38.3 8.1e-35 120.4 16.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Dynamin_M PF01031.20 KER29826.1 - 1.1e-75 254.5 0.0 4.2e-75 252.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KER29826.1 - 1.8e-13 50.9 0.0 3.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KER29826.1 - 1.4e-11 44.3 6.8 5.6e-08 32.8 0.7 2.6 1 1 1 2 2 2 2 Dynamin GTPase effector domain PH PF00169.29 KER29826.1 - 1.5e-05 25.5 0.1 2.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KER29826.1 - 0.048 14.1 0.6 0.23 11.9 0.6 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain COesterase PF00135.28 KER29830.1 - 1.1e-56 192.8 0.0 2.2e-56 191.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KER29830.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SKG6 PF08693.10 KER29832.1 - 0.0006 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DiS_P_DiS PF06750.13 KER29832.1 - 0.041 14.0 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Secretogranin_V PF05281.11 KER29832.1 - 0.044 13.4 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Innexin PF00876.18 KER29833.1 - 3.6e-168 559.3 27.0 3.1e-106 355.6 13.4 2.1 2 0 0 2 2 2 2 Innexin Kelch_1 PF01344.25 KER29837.1 - 1.4e-33 114.2 2.0 3e-09 36.3 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KER29837.1 - 1.4e-23 82.4 1.7 0.00066 19.9 0.0 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KER29837.1 - 2.4e-20 72.3 0.4 1.3e-05 25.0 0.0 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KER29837.1 - 5.4e-20 71.2 4.9 3.1e-05 24.1 0.1 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 KER29837.1 - 2.2e-16 59.8 0.4 9.9e-16 57.7 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 KER29837.1 - 2.4e-13 49.7 9.7 0.0051 16.8 0.0 6.5 6 0 0 6 6 6 3 Kelch motif BTB PF00651.31 KER29837.1 - 1.1e-10 41.7 0.1 1.9e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 KER29837.1 - 2.1e-07 30.7 2.0 0.029 14.3 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Gcd10p PF04189.13 KER29838.1 - 4.3e-28 98.3 0.2 4.7e-28 98.2 0.2 1.0 1 0 0 1 1 1 1 Gcd10p family DUF2247 PF10004.9 KER29838.1 - 0.027 14.2 0.0 0.029 14.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) KCT2 PF17818.1 KER29838.1 - 0.051 13.7 0.1 0.058 13.5 0.1 1.1 1 0 0 1 1 1 0 Keratinocyte-associated gene product HAUS4 PF14735.6 KER29839.1 - 0.00019 21.2 6.3 0.00029 20.6 6.3 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 ABC_tran_CTD PF16326.5 KER29839.1 - 0.036 14.3 0.3 0.19 12.0 0.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Synaptonemal_3 PF15191.6 KER29839.1 - 0.06 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 TMF_TATA_bd PF12325.8 KER29839.1 - 0.089 13.0 1.2 0.29 11.4 1.2 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Metal_resist PF13801.6 KER29839.1 - 0.44 10.7 2.9 15 5.8 0.4 2.4 2 0 0 2 2 2 0 Heavy-metal resistance APG6_N PF17675.1 KER29839.1 - 1.5 9.3 7.8 0.075 13.6 1.5 2.1 3 0 0 3 3 3 0 Apg6 coiled-coil region ASCH PF04266.14 KER29840.1 - 1.5e-11 44.8 0.0 4.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 KER29840.1 - 2.9e-11 43.2 10.8 2.9e-11 43.2 10.8 3.0 3 0 0 3 3 3 2 Putative zinc finger motif, C2HC5-type Caskin-tail PF16632.5 KER29840.1 - 0.12 12.8 0.2 3.5 8.1 0.1 2.8 2 0 0 2 2 2 0 C-terminal region of Caskin XPA_C PF05181.12 KER29841.1 - 6.2e-22 77.3 0.8 4.8e-21 74.5 0.1 2.4 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 KER29841.1 - 4.2e-12 45.9 8.9 4.2e-12 45.9 8.9 2.6 3 0 0 3 3 3 1 XPA protein N-terminal zf-TFIIB PF13453.6 KER29841.1 - 1.2 8.6 5.8 5.2 6.5 2.1 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger SH3_1 PF00018.28 KER29842.1 - 2.1e-10 40.0 0.0 5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER29842.1 - 3.7e-08 33.1 0.0 8.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER29842.1 - 2.5e-07 30.3 0.0 5.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PP-binding PF00550.25 KER29843.1 - 1.1e-07 32.1 0.1 2.4e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KER29844.1 - 7.3e-13 47.9 0.0 4.9e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KER29844.1 - 0.0001 22.6 0.8 0.00018 21.8 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site zf-C2H2 PF00096.26 KER29846.1 - 7e-12 45.1 19.6 3.2e-05 24.2 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER29846.1 - 1.7e-09 37.6 12.9 2.1e-06 27.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER29846.1 - 2.8e-09 37.0 17.1 0.0021 18.7 1.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER29846.1 - 3.7e-06 26.8 12.5 0.00024 21.0 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER29846.1 - 0.031 14.6 6.2 8.7 6.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER29846.1 - 0.07 13.5 6.4 5 7.6 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_4 PF07975.12 KER29846.1 - 0.39 11.0 6.0 3.6 7.9 0.1 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain zf-MYST PF17772.1 KER29846.1 - 0.44 10.2 5.7 0.5 10.0 0.7 3.0 1 1 1 2 2 2 0 MYST family zinc finger domain Zf_RING PF16744.5 KER29846.1 - 3 8.0 8.3 22 5.2 0.2 3.7 1 1 2 3 3 3 0 KIAA1045 RING finger UDPGP PF01704.18 KER29847.1 - 3e-132 441.2 0.0 1.7e-84 283.8 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase PQ-loop PF04193.14 KER29848.1 - 6.7e-18 64.2 2.2 1.3e-17 63.3 2.2 1.5 1 0 0 1 1 1 1 PQ loop repeat LSM PF01423.22 KER29848.1 - 1e-07 31.5 0.3 2e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 LSM domain MtN3_slv PF03083.16 KER29848.1 - 0.011 15.8 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CBFD_NFYB_HMF PF00808.23 KER29850.1 - 3.9e-29 100.7 0.7 6.2e-29 100.1 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KER29850.1 - 0.00012 22.5 0.0 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KER29850.1 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KER29850.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF4407 PF14362.6 KER29851.1 - 0.5 9.7 3.4 0.93 8.8 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Viral_Rep PF02407.16 KER29852.1 - 2.7e-10 40.3 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Putative viral replication protein RNA_helicase PF00910.22 KER29852.1 - 0.0076 16.6 0.5 0.017 15.5 0.5 1.6 1 0 0 1 1 1 1 RNA helicase HTH_7 PF02796.15 KER29852.1 - 0.038 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF433 PF04255.14 KER29852.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF3525 PF12039.8 KER29852.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Adaptin_N PF01602.20 KER29852.1 - 0.22 10.1 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region THOC7 PF05615.13 KER29853.1 - 3.9e-16 59.5 6.4 4.1e-16 59.5 6.4 1.0 1 0 0 1 1 1 1 Tho complex subunit 7 DUF4619 PF15398.6 KER29853.1 - 0.1 12.1 1.4 0.11 12.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) polyprenyl_synt PF00348.17 KER29854.1 - 8.6e-64 215.0 0.0 1.1e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CTP_transf_like PF01467.26 KER29854.1 - 0.047 13.9 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase-like ubiquitin PF00240.23 KER29857.1 - 1.5e-28 98.3 0.6 1.7e-28 98.2 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KER29857.1 - 2.2e-17 62.7 0.5 2.4e-17 62.5 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KER29857.1 - 7.9e-06 26.3 0.1 2.8e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KER29857.1 - 0.00036 20.4 0.0 0.00044 20.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KER29857.1 - 0.053 13.6 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KER29857.1 - 0.056 13.5 0.7 4 7.6 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Sema PF01403.19 KER29858.1 - 1.6e-21 76.7 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.19 KER29858.1 - 2.2e-08 34.2 3.7 2.2e-08 34.2 3.7 3.6 4 0 0 4 4 4 1 Thrombospondin type 1 domain DUF4201 PF13870.6 KER29860.1 - 1.4e-41 142.2 26.4 1.4e-41 142.2 26.4 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.11 KER29860.1 - 0.0035 17.2 15.7 0.0058 16.5 5.6 2.8 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) Scaffolding_pro PF11418.8 KER29860.1 - 1.4 9.5 11.1 5.8 7.5 0.5 4.3 3 1 0 3 3 3 0 Phi29 scaffolding protein ubiquitin PF00240.23 KER29861.1 - 7e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KER29861.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KER29861.1 - 0.019 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain PHD PF00628.29 KER29862.1 - 2.3e-17 62.6 31.0 4.5e-12 45.7 6.0 3.6 3 1 1 4 4 4 2 PHD-finger RVT_1 PF00078.27 KER29862.1 - 3.9e-17 62.5 0.0 6.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Requiem_N PF14051.6 KER29862.1 - 4.1e-14 52.5 0.1 1.2e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. zf-C2H2_4 PF13894.6 KER29862.1 - 0.015 16.1 0.4 0.015 16.1 0.4 5.6 7 0 0 7 7 7 0 C2H2-type zinc finger zf-met PF12874.7 KER29862.1 - 0.048 14.1 0.4 0.048 14.1 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KER29862.1 - 0.066 12.9 0.6 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PHD_2 PF13831.6 KER29862.1 - 4 7.1 16.0 0.14 11.7 1.0 3.4 3 0 0 3 3 3 0 PHD-finger Lar_restr_allev PF14354.6 KER29862.1 - 6.7 7.2 17.3 9.4e+02 0.3 15.9 3.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar PP2C PF00481.21 KER29864.1 - 2.1e-30 106.2 0.0 2.3e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 KER29866.1 - 8.7e-64 214.5 0.0 1.5e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 KER29866.1 - 2.1e-38 132.1 0.0 1.6e-35 122.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER29866.1 - 5.2e-24 85.0 0.0 9.3e-23 80.9 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Yuri_gagarin PF15934.5 KER29866.1 - 0.016 15.1 1.0 0.059 13.2 0.1 2.1 2 0 0 2 2 2 0 Yuri gagarin Dynein_AAA_lid PF17852.1 KER29866.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain HALZ PF02183.18 KER29867.1 - 0.067 13.4 0.4 1.3 9.3 0.4 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med8 PF10232.9 KER29869.1 - 2.3e-33 115.8 2.4 3.1e-33 115.3 2.4 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RVT_1 PF00078.27 KER29869.1 - 9.3e-06 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF16 PF01519.16 KER29869.1 - 0.025 15.1 0.1 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Lipid_DES PF08557.10 KER29870.1 - 2.9e-22 77.9 0.5 6.2e-22 76.8 0.5 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 KER29870.1 - 8.9e-20 71.6 15.3 8.9e-20 71.6 15.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase IF-2B PF01008.17 KER29871.1 - 1.2e-42 146.1 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Proteasome PF00227.26 KER29875.1 - 8.4e-49 165.6 0.1 1.1e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KER29875.1 - 3.4e-11 42.6 0.0 6.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SGTA_dimer PF16546.5 KER29875.1 - 0.053 13.3 0.1 0.097 12.5 0.1 1.4 1 0 0 1 1 1 0 Homodimerisation domain of SGTA SIR2 PF02146.17 KER29876.1 - 2.2e-58 197.1 0.0 3.1e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-RING_7 PF02591.15 KER29876.1 - 0.00015 21.9 1.2 0.0004 20.5 1.2 1.8 1 0 0 1 1 1 1 C4-type zinc ribbon domain zf-DNL PF05180.12 KER29876.1 - 0.054 13.4 1.4 0.12 12.4 1.4 1.5 1 0 0 1 1 1 0 DNL zinc finger KH_1 PF00013.29 KER29878.1 - 6e-31 106.1 5.4 7e-18 64.2 1.5 3.8 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 KER29878.1 - 2.9e-07 30.2 0.2 0.0016 18.2 0.1 2.5 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 KER29878.1 - 0.00017 21.5 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 KH-like RNA-binding domain KH_4 PF13083.6 KER29878.1 - 0.0023 17.8 0.0 0.88 9.5 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KER29878.1 - 0.04 14.0 0.7 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain FEZ PF07763.13 KER29878.1 - 0.04 13.6 1.1 0.069 12.9 1.1 1.3 1 0 0 1 1 1 0 FEZ-like protein R3H PF01424.22 KER29879.1 - 4.5e-12 45.8 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KER29879.1 - 8.2e-07 29.0 37.3 2.7e-06 27.3 13.2 13.3 16 1 1 17 17 17 7 NF-X1 type zinc finger Rft-1 PF04506.13 KER29881.1 - 5.2e-97 325.7 12.5 8.2e-97 325.1 12.5 1.2 1 0 0 1 1 1 1 Rft protein HLH PF00010.26 KER29881.1 - 1.5e-13 50.5 1.7 1.9e-13 50.1 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Polysacc_synt_C PF14667.6 KER29881.1 - 5.7e-05 23.2 1.3 5.7e-05 23.2 1.3 4.0 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF5480 PF17576.2 KER29884.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5480) AA_permease_2 PF13520.6 KER29885.1 - 2e-73 247.7 75.8 1.4e-40 139.5 35.2 3.9 4 0 0 4 4 4 2 Amino acid permease AA_permease PF00324.21 KER29885.1 - 2.7e-51 174.7 72.6 5.7e-28 97.7 34.1 3.8 4 0 0 4 4 4 2 Amino acid permease DUF2981 PF11200.8 KER29885.1 - 0.0028 17.4 0.6 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2981) AA_permease_2 PF13520.6 KER29886.1 - 2.5e-41 141.9 37.1 2.5e-41 141.9 37.1 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KER29886.1 - 5.4e-31 107.7 28.5 5.4e-31 107.7 28.5 2.0 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 KER29886.1 - 2.3e-07 30.8 0.7 2.3e-07 30.8 0.7 4.5 4 0 0 4 4 4 1 C-terminus of AA_permease Glyco_transf_49 PF13896.6 KER29887.1 - 9.3e-58 196.1 2.9 2.5e-46 158.5 0.6 2.5 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 KER29887.1 - 0.14 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_8 PF01501.20 KER29887.1 - 0.19 11.2 3.7 1.5 8.3 0.1 3.1 3 1 1 4 4 4 0 Glycosyl transferase family 8 CDC45 PF02724.14 KER29889.1 - 0.036 12.4 16.1 0.036 12.4 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KER29889.1 - 0.14 10.2 26.8 0.16 10.0 26.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KER29889.1 - 0.26 9.5 23.6 0.29 9.3 23.6 1.0 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 KER29889.1 - 0.41 10.5 8.4 0.45 10.4 8.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Utp14 PF04615.13 KER29889.1 - 1 7.9 15.0 1.4 7.4 15.0 1.2 1 0 0 1 1 1 0 Utp14 protein eIF-3c_N PF05470.12 KER29889.1 - 1.9 6.7 9.1 2.1 6.6 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.12 KER29889.1 - 3.5 6.9 18.7 4 6.8 18.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 KER29889.1 - 7 6.0 25.9 8.1 5.8 25.9 1.1 1 0 0 1 1 1 0 SDA1 Alg14 PF08660.11 KER29890.1 - 1.1e-59 201.3 0.0 1.3e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like zf-C4 PF00105.18 KER29891.1 - 2.5e-23 82.3 12.8 4.7e-23 81.4 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER29891.1 - 6.8e-16 58.5 0.3 9.6e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor Arm-DNA-bind_5 PF17293.2 KER29892.1 - 0.15 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain TPR_12 PF13424.6 KER29893.1 - 2.2e-19 69.5 0.7 1.2e-08 35.2 0.1 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KER29893.1 - 3.5e-12 45.8 0.6 2.9e-06 27.0 0.3 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KER29893.1 - 2e-09 37.3 1.4 3.8e-08 33.1 0.1 2.9 1 1 3 4 4 4 1 MalT-like TPR region TPR_2 PF07719.17 KER29893.1 - 1.6e-07 30.9 0.1 0.012 15.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER29893.1 - 7.5e-07 28.9 2.7 0.087 13.1 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER29893.1 - 4.7e-05 23.8 5.4 0.19 12.2 0.4 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KER29893.1 - 0.0013 18.6 1.1 0.18 11.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER29893.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_1 PF00515.28 KER29893.1 - 0.0016 18.2 1.5 0.022 14.6 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER29893.1 - 0.0033 18.1 1.1 4.1 8.5 0.1 4.6 5 1 1 6 6 5 1 Tetratricopeptide repeat GED PF02212.18 KER29893.1 - 0.019 15.1 2.0 0.091 12.9 2.0 2.2 1 1 0 1 1 1 0 Dynamin GTPase effector domain T3SS_basalb_I PF17001.5 KER29893.1 - 1 10.0 4.6 0.74 10.5 0.8 2.8 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Fis1_TPR_C PF14853.6 KER29893.1 - 1.7 8.7 5.6 1.5 9.0 0.2 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF5446 PF17522.2 KER29893.1 - 3 8.1 8.6 0.35 11.1 1.8 3.0 3 0 0 3 3 2 0 Family of unknown function (DUF5446) MRP-S24 PF14955.6 KER29894.1 - 9e-58 194.0 0.3 1.3e-57 193.6 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 Acyl-CoA_dh_M PF02770.19 KER29895.1 - 1.7e-18 66.6 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KER29895.1 - 7.5e-05 23.0 1.0 0.00024 21.4 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Tmpp129 PF10272.9 KER29896.1 - 1.7e-69 234.8 0.0 2.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Putative transmembrane protein precursor LOH1CR12 PF10158.9 KER29896.1 - 0.0036 17.3 0.0 0.065 13.3 0.1 2.2 2 0 0 2 2 2 1 Tumour suppressor protein Ank_2 PF12796.7 KER29898.1 - 3e-14 53.3 0.2 6.2e-14 52.3 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER29898.1 - 1.2e-12 48.1 1.2 6.6e-05 23.4 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER29898.1 - 1.7e-12 46.3 0.4 6.6e-05 23.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KER29898.1 - 3.9e-12 46.0 1.5 7.6e-06 26.1 0.4 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KER29898.1 - 8.4e-12 45.1 1.2 4.8e-06 26.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 KER29898.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Nop16 PF09420.10 KER29898.1 - 0.065 13.3 2.7 2.6 8.0 0.1 3.2 2 1 1 3 3 3 0 Ribosome biogenesis protein Nop16 SH3_2 PF07653.17 KER29898.1 - 0.19 11.4 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain LETM1 PF07766.13 KER29902.1 - 5.7e-96 321.0 3.8 5.7e-96 321.0 3.8 2.1 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 KER29902.1 - 8.7e-05 22.9 2.1 0.0049 17.3 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair FAM76 PF16046.5 KER29902.1 - 0.0018 17.7 3.2 0.0018 17.7 3.2 2.4 3 0 0 3 3 3 1 FAM76 protein EF-hand_1 PF00036.32 KER29902.1 - 0.0048 16.3 0.2 0.053 13.1 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KER29902.1 - 0.014 15.3 0.3 3.7 7.7 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain SlyX PF04102.12 KER29902.1 - 1.4 9.6 5.8 4.8 7.9 0.8 3.4 1 1 1 2 2 2 0 SlyX Phasin PF05597.11 KER29902.1 - 3.5 7.7 9.1 11 6.1 6.3 2.6 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EF-G-binding_N PF07299.11 KER29902.1 - 9.6 6.8 8.8 1.1 9.8 0.3 3.6 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal FAD_binding_7 PF03441.14 KER29903.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase DZF PF07528.14 KER29904.1 - 1.2e-61 208.5 0.0 1.8e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 DZF domain Nrap_D5 PF17406.2 KER29904.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Ferlin_C PF16165.5 KER29905.1 - 2.5e-27 95.7 0.7 2.9e-24 85.8 0.1 2.5 1 1 1 2 2 2 2 Ferlin C-terminus C2 PF00168.30 KER29905.1 - 6.2e-26 90.7 0.1 2.6e-13 50.1 0.1 5.7 4 1 0 4 4 4 3 C2 domain FerI PF08151.12 KER29905.1 - 1.2e-17 63.7 0.3 2.6e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 FerI (NUC094) domain FerB PF08150.12 KER29905.1 - 6.1e-14 52.4 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain Pex24p PF06398.11 KER29905.1 - 0.0022 17.0 0.9 0.0022 17.0 0.9 2.5 3 0 0 3 3 3 1 Integral peroxisomal membrane peroxin FerA PF08165.11 KER29905.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain dsRBD2 PF17842.1 KER29905.1 - 0.048 13.9 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 WYL PF13280.6 KER29905.1 - 0.085 12.9 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 WYL domain C2 PF00168.30 KER29908.1 - 1.6e-92 304.6 0.4 1e-20 73.9 0.0 8.5 7 1 0 7 7 7 7 C2 domain Ferlin_C PF16165.5 KER29908.1 - 1.4e-24 86.8 1.6 2.2e-22 79.7 0.3 2.4 1 1 1 2 2 2 2 Ferlin C-terminus FerB PF08150.12 KER29908.1 - 2.6e-24 85.6 0.0 5.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain FerA PF08165.11 KER29908.1 - 2.6e-19 68.9 0.8 7.3e-19 67.5 0.5 2.0 2 0 0 2 2 2 1 FerA (NUC095) domain FerI PF08151.12 KER29908.1 - 3.6e-19 68.6 0.6 8.9e-19 67.3 0.6 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain Pex24p PF06398.11 KER29908.1 - 1.2e-06 27.7 18.9 2.4e-05 23.5 11.4 3.3 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin PTEN_C2 PF10409.9 KER29908.1 - 7.8e-05 22.4 0.6 0.12 12.1 0.0 3.1 3 0 0 3 3 3 2 C2 domain of PTEN tumour-suppressor protein PI3K_C2 PF00792.24 KER29908.1 - 0.022 14.7 0.0 4.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 bZIP_1 PF00170.21 KER29909.1 - 1.3e-16 60.4 12.1 2.9e-16 59.3 12.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KER29909.1 - 4.1e-08 33.2 12.4 9.3e-08 32.0 12.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KER29909.1 - 0.013 16.0 6.8 0.033 14.7 6.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Pox_F12L PF03337.13 KER29909.1 - 0.025 12.8 0.2 0.048 11.8 0.2 1.4 1 0 0 1 1 1 0 Poxvirus F12L protein DUF4618 PF15397.6 KER29909.1 - 0.059 12.8 0.2 0.099 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Sif PF06767.11 KER29909.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Sif protein ADP_ribosyl_GH PF03747.14 KER29909.1 - 0.38 10.4 7.9 0.053 13.3 1.0 2.7 3 1 0 3 3 3 0 ADP-ribosylglycohydrolase ASD2 PF08687.11 KER29909.1 - 0.91 9.0 6.8 0.1 12.1 1.0 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF3339 PF11820.8 KER29910.1 - 0.021 15.0 0.4 0.035 14.3 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3339) TMEM132D_N PF15705.5 KER29910.1 - 0.055 13.3 0.2 0.16 11.8 0.1 1.8 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term FeS_assembly_P PF01883.19 KER29912.1 - 5.5e-14 52.1 0.0 9.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Glyco_transf_8 PF01501.20 KER29912.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF1071 PF06378.11 KER29912.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) IL6Ra-bind PF09240.10 KER29912.1 - 0.12 12.9 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding QVR PF17064.5 KER29914.1 - 7.7e-05 22.9 5.5 0.00015 22.0 5.5 1.5 1 1 0 1 1 1 1 Sleepless protein DUF753 PF05444.12 KER29914.1 - 0.56 10.2 9.5 0.045 13.7 2.5 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF753) LRRC37AB_C PF14914.6 KER29915.1 - 0.0023 17.8 0.1 0.0027 17.6 0.1 1.1 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Renin_r PF07850.14 KER29915.1 - 0.0024 18.4 0.1 0.0031 18.1 0.1 1.2 1 0 0 1 1 1 1 Renin receptor-like protein TMEM154 PF15102.6 KER29915.1 - 0.0037 17.2 0.2 0.0044 16.9 0.2 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 KER29915.1 - 0.059 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Shisa PF13908.6 KER29915.1 - 0.12 12.6 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Tubulin PF00091.25 KER29918.1 - 2.9e-52 177.7 0.0 4.3e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER29918.1 - 1.2e-49 167.7 0.0 1.8e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER29918.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pkinase PF00069.25 KER29919.1 - 5.8e-74 248.8 0.0 9.5e-36 123.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 KER29919.1 - 1.9e-18 66.8 0.0 6e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 KER29919.1 - 1.8e-17 63.5 0.0 3.4e-07 29.8 0.0 3.0 2 2 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KER29919.1 - 1.2e-08 34.5 0.1 0.005 16.2 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KER29919.1 - 1.9e-08 34.0 0.0 0.007 15.7 0.0 2.3 2 0 0 2 2 2 2 Ecdysteroid kinase Choline_kinase PF01633.20 KER29919.1 - 2.1e-06 27.5 0.5 0.07 12.7 0.1 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 KER29919.1 - 2.3e-06 27.7 0.1 0.094 12.6 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Atx10homo_assoc PF09759.9 KER29919.1 - 0.00012 22.1 0.0 0.92 9.6 0.0 2.6 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Pox_ser-thr_kin PF05445.11 KER29919.1 - 0.0054 15.8 1.6 1.8 7.5 0.1 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KER29919.1 - 0.0054 15.8 0.3 2.8 6.9 0.0 2.3 2 0 0 2 2 2 2 Seadornavirus VP7 CybS PF05328.12 KER29919.1 - 0.084 12.6 0.2 24 4.6 0.0 2.9 4 0 0 4 4 4 0 CybS, succinate dehydrogenase cytochrome B small subunit ERAP1_C PF11838.8 KER29920.1 - 0.0084 15.7 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain IBN_N PF03810.19 KER29920.1 - 0.014 15.3 0.1 0.84 9.6 0.0 3.1 3 0 0 3 3 3 0 Importin-beta N-terminal domain Xpo1 PF08389.12 KER29920.1 - 0.055 13.5 19.3 0.086 12.9 0.1 5.2 7 0 0 7 7 7 0 Exportin 1-like protein NTP_transferase PF00483.23 KER29921.1 - 3.1e-46 158.0 0.0 4.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KER29921.1 - 9.6e-11 41.0 3.4 2.4e-07 30.2 0.7 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KER29921.1 - 3.2e-09 37.4 0.0 5e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KER29921.1 - 0.0086 15.8 1.9 2.9 7.7 0.3 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KER29921.1 - 0.066 12.1 0.4 0.26 10.2 0.4 1.8 1 1 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 KER29921.1 - 0.066 11.3 0.1 0.092 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Ndc1_Nup PF09531.10 KER29923.1 - 7.5 5.1 6.2 8 5.0 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4218 PF13960.6 KER29925.1 - 1.3e-05 24.8 0.2 2.3e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) LIM PF00412.22 KER29926.1 - 5e-13 49.1 18.8 7.3e-08 32.5 4.2 2.4 2 0 0 2 2 2 2 LIM domain DUF2175 PF09943.9 KER29926.1 - 0.061 13.6 1.4 0.061 13.6 1.4 2.9 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Jas PF16135.5 KER29926.1 - 0.32 11.2 0.2 0.32 11.2 0.2 3.3 3 0 0 3 3 3 0 TPL-binding domain in jasmonate signalling DUF2685 PF10886.8 KER29926.1 - 0.67 10.2 11.4 0.41 10.9 4.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2685) RVT_1 PF00078.27 KER29927.1 - 1.1e-29 103.6 0.0 2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAS_11 PF14598.6 KER29927.1 - 5.3e-13 49.1 0.1 5.5e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 PAS domain HLH PF00010.26 KER29927.1 - 8.1e-12 44.9 1.1 1.5e-11 44.0 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 KER29927.1 - 3.2e-08 33.5 0.0 0.0014 18.7 0.0 3.2 3 0 0 3 3 3 2 PAS fold Exo_endo_phos_2 PF14529.6 KER29927.1 - 4.2e-08 33.1 0.1 9.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PAS_4 PF08448.10 KER29927.1 - 3.3e-06 27.3 0.0 0.066 13.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KER29927.1 - 3.3e-05 24.1 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KER29927.1 - 0.00011 22.4 0.0 0.0049 17.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold DEAD PF00270.29 KER29928.1 - 1.6e-37 128.9 0.0 3.4e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER29928.1 - 1.1e-24 86.9 0.2 5.2e-24 84.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER29928.1 - 3.8e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KER29928.1 - 0.0068 16.7 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER29928.1 - 0.073 13.3 0.1 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DKCLD PF08068.12 KER29928.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain RasGEF_N PF00618.20 KER29930.1 - 2.1e-18 66.5 0.3 4.9e-18 65.3 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KER29930.1 - 4.4e-18 66.1 0.0 2.1e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain MOZ_SAS PF01853.18 KER29931.1 - 9.1e-76 253.5 0.0 1.5e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KER29931.1 - 2.8e-22 78.1 5.8 2.8e-22 78.1 5.8 2.4 3 0 0 3 3 3 1 MYST family zinc finger domain Tudor-knot PF11717.8 KER29931.1 - 7.8e-14 51.3 0.8 1.7e-13 50.2 0.8 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KER29931.1 - 0.031 14.7 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KER29931.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HCV_env PF01539.17 KER29931.1 - 0.15 11.8 0.3 5.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 RVT_1 PF00078.27 KER29932.1 - 7.9e-14 51.7 0.0 2.7e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abdominal-A PF12407.8 KER29932.1 - 0.084 12.5 3.2 0.39 10.3 3.2 2.2 1 0 0 1 1 1 0 Homeobox protein GP57 PF17594.2 KER29932.1 - 0.092 12.5 0.8 0.59 9.9 0.8 2.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 NEMP PF10225.9 KER29932.1 - 0.1 12.3 3.8 5.7 6.5 0.3 3.1 2 1 1 3 3 3 0 NEMP family HTH_9 PF08221.11 KER29933.1 - 3.8e-06 26.9 15.4 0.11 12.6 0.1 6.2 6 0 0 6 6 6 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KER29933.1 - 1.9e-05 24.6 0.6 7.5e-05 22.6 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 TrmB PF01978.19 KER29933.1 - 0.042 13.7 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CAMSAP_CC1 PF17095.5 KER29933.1 - 0.087 12.7 3.5 0.21 11.5 3.5 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF4884 PF16225.5 KER29933.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) Exonuc_VII_L PF02601.15 KER29933.1 - 0.2 11.2 5.1 0.31 10.6 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1057 PF06342.12 KER29934.1 - 0.058 12.4 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PDEase_I PF00233.19 KER29935.1 - 3.7e-80 269.1 1.4 6.4e-80 268.3 1.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KER29935.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 HD domain Glyco_transf_7N PF13733.6 KER29936.1 - 1.4e-29 102.4 0.0 2.6e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KER29936.1 - 8.1e-21 73.5 0.1 1.7e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DnaJ_C PF01556.18 KER29937.1 - 1.8e-40 138.4 0.0 2.8e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KER29937.1 - 4.4e-25 87.6 1.6 7.2e-25 86.9 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KER29937.1 - 1.9e-13 50.6 20.5 3.1e-13 49.9 20.5 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.10 KER29937.1 - 2.4 8.0 9.7 11 5.9 2.9 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain Frag1 PF10277.9 KER29938.1 - 3.3e-28 98.7 23.7 3.9e-28 98.5 23.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF21 PF01595.20 KER29938.1 - 0.0053 16.5 0.3 0.0053 16.5 0.3 1.9 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Frag1 PF10277.9 KER29940.1 - 2.9e-24 85.8 15.8 3.5e-24 85.6 15.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PET117 PF15786.5 KER29940.1 - 0.017 15.4 1.4 0.037 14.3 0.1 2.2 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Frag1 PF10277.9 KER29942.1 - 5.8e-17 62.0 11.6 3.4e-12 46.4 11.4 2.9 2 1 0 2 2 2 2 Frag1/DRAM/Sfk1 family DUF1772 PF08592.11 KER29942.1 - 0.023 15.0 1.4 0.043 14.1 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2554 PF10829.8 KER29942.1 - 0.03 14.7 0.9 2 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Glyco_hydro_31 PF01055.26 KER29943.1 - 1.9e-64 218.5 0.0 2.9e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KER29943.1 - 5.9e-18 65.2 0.0 9.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 KER29943.1 - 2.4e-09 36.9 5.3 4.5e-09 36.0 5.3 1.5 1 0 0 1 1 1 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 KER29943.1 - 3.5e-05 24.0 0.1 0.00013 22.2 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like GDPD_2 PF13653.6 KER29943.1 - 0.0032 17.9 0.8 0.016 15.7 0.2 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DIX PF00778.17 KER29944.1 - 7.8e-29 99.3 1.1 9.6e-27 92.6 1.1 2.4 1 1 0 1 1 1 1 DIX domain Dishevelled PF02377.15 KER29944.1 - 1.9e-26 93.5 13.9 1.9e-26 93.5 13.9 3.6 3 0 0 3 3 3 1 Dishevelled specific domain DEP PF00610.21 KER29944.1 - 7.8e-17 61.1 0.1 2e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.24 KER29944.1 - 2.1e-16 60.0 0.6 4.5e-16 59.0 0.6 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER29944.1 - 0.00034 20.4 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER29944.1 - 0.0096 16.2 0.9 0.035 14.4 0.1 2.2 2 0 0 2 2 2 1 PDZ domain APP_E2 PF12925.7 KER29946.1 - 0.027 14.2 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein PRP38 PF03371.15 KER29948.1 - 1.3e-56 191.2 0.0 1.7e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Mito_carr PF00153.27 KER29949.1 - 1.2e-55 185.4 0.3 7.9e-22 77.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ku_PK_bind PF08785.11 KER29949.1 - 0.081 13.1 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Ku C terminal domain like Transferrin PF00405.17 KER29949.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Transferrin Myb_DNA-bind_2 PF08914.11 KER29950.1 - 1.9e-19 69.6 0.8 5.4e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 KER29950.1 - 0.00011 22.5 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_6 PF13921.6 KER29950.1 - 0.014 15.6 0.1 0.044 14.1 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3546 PF12066.8 KER29951.1 - 7.3e-31 106.6 0.1 1.5e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KER29951.1 - 1.4e-26 94.1 0.1 5.1e-26 92.2 0.1 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 GAS PF13851.6 KER29952.1 - 2.6e-49 167.3 23.2 2.6e-49 167.3 23.2 3.6 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding RVT_1 PF00078.27 KER29952.1 - 2.3e-26 92.7 0.1 7.4e-20 71.4 0.0 3.3 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) NapD PF03927.13 KER29952.1 - 0.026 14.6 0.2 0.1 12.7 0.2 2.1 1 0 0 1 1 1 0 NapD protein DUF1729 PF08354.10 KER29952.1 - 0.05 12.5 12.3 0.28 10.1 3.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) Flagellin_C PF00700.21 KER29952.1 - 0.28 11.6 12.4 0.039 14.3 1.7 3.8 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region NPV_P10 PF05531.12 KER29952.1 - 0.95 10.0 4.5 2.2 8.8 1.0 3.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KER29952.1 - 2.5 8.2 22.1 13 5.8 7.2 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNARE PF05739.19 KER29954.1 - 4.3e-17 61.8 0.9 1e-16 60.7 0.9 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KER29954.1 - 0.00064 19.4 1.4 0.00064 19.4 1.4 2.6 3 1 0 3 3 3 1 Syntaxin DUF5345 PF17280.2 KER29954.1 - 0.018 15.0 0.2 0.018 15.0 0.2 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5345) TRP PF06011.12 KER29954.1 - 0.09 11.5 0.3 0.092 11.5 0.3 1.3 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1664 PF07889.12 KER29954.1 - 2 8.5 6.8 7.5 6.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ufd2P_core PF10408.9 KER29955.1 - 6.3e-91 305.9 0.0 7.2e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 KER29955.1 - 3.8e-25 87.8 0.1 8.9e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KER29955.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SH2 PF00017.24 KER29957.1 - 2.6e-08 33.9 0.0 1.3e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 SH2 domain ArsA_ATPase PF02374.15 KER29957.1 - 0.089 12.0 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Anion-transporting ATPase Cep57_CLD_2 PF14197.6 KER29959.1 - 0.11 12.6 2.6 0.26 11.4 2.6 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lebercilin PF15619.6 KER29959.1 - 0.15 11.7 1.4 0.28 10.8 1.4 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GOLGA2L5 PF15070.6 KER29959.1 - 0.63 8.6 3.0 0.19 10.3 0.2 1.5 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KER29959.1 - 4.4 7.1 5.5 0.43 10.4 0.6 1.7 2 0 0 2 2 2 0 Septum formation initiator DEK_C PF08766.11 KER29962.1 - 9.1e-16 57.5 0.0 1.3e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 DEK C terminal domain PIP49_C PF12260.8 KER29962.1 - 5.2e-13 49.0 1.6 1.7e-07 31.1 0.0 3.4 3 1 0 3 3 3 2 Protein-kinase domain of FAM69 SAP PF02037.27 KER29962.1 - 0.002 17.8 0.5 0.0045 16.7 0.5 1.6 1 0 0 1 1 1 1 SAP domain PGA2 PF07543.12 KER29962.1 - 1.6 8.7 18.0 5.9 6.9 10.1 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4786 PF16027.5 KER29964.1 - 0.047 14.3 0.0 8 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4786) Arteri_Gl PF00951.18 KER29964.1 - 0.086 12.7 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Linker_histone PF00538.19 KER29965.1 - 7.6e-08 32.6 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Mitofilin PF09731.9 KER29965.1 - 2.4 6.9 13.2 2.6 6.8 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Histone PF00125.24 KER29968.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER29968.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER29968.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KER29968.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 KER29968.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Histone PF00125.24 KER29969.1 - 6.2e-23 81.6 1.4 7.8e-23 81.3 1.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KER29969.1 - 3.2e-06 27.3 0.0 8.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KER29969.1 - 0.00098 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KER29969.1 - 0.0026 17.8 0.5 0.003 17.6 0.5 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 KER29969.1 - 0.0031 17.5 0.4 0.0033 17.4 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Guanylate_cyc PF00211.20 KER29970.1 - 3.9e-25 88.5 0.0 5.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EGF_CA PF07645.15 KER29973.1 - 5.3e-29 100.2 57.6 1.5e-10 41.1 9.5 11.7 8 4 1 10 10 10 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 KER29973.1 - 2.2e-16 59.8 55.3 1e-08 35.3 6.5 12.7 11 3 1 12 12 12 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KER29973.1 - 3.1e-10 39.8 92.0 3e-05 23.9 1.1 10.4 9 1 0 9 9 9 6 Complement Clr-like EGF-like EGF_2 PF07974.13 KER29973.1 - 0.00085 19.6 14.0 0.00085 19.6 14.0 12.9 13 2 0 13 13 13 4 EGF-like domain hEGF PF12661.7 KER29973.1 - 0.001 19.6 3.4 0.001 19.6 3.4 14.2 13 2 0 13 13 13 6 Human growth factor-like EGF EGF PF00008.27 KER29973.1 - 0.0077 16.5 8.1 0.0077 16.5 8.1 13.0 13 0 0 13 13 13 6 EGF-like domain EGF_Tenascin PF18720.1 KER29973.1 - 0.0096 15.9 7.9 0.0096 15.9 7.9 9.3 9 2 0 9 9 9 1 Tenascin EGF domain Plasmod_Pvs28 PF06247.11 KER29973.1 - 0.021 15.1 4.0 0.021 15.1 4.0 9.5 9 1 0 9 9 9 0 Pvs28 EGF domain Mito_carr PF00153.27 KER29975.1 - 4.3e-38 129.1 8.5 1.8e-11 43.8 0.6 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein DUF1965 PF09248.10 KER29977.1 - 0.0071 16.1 0.4 0.023 14.5 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1965) Rad4 PF03835.15 KER29977.1 - 0.018 14.7 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain CBS PF00571.28 KER29979.1 - 1.2e-13 51.3 0.4 0.00045 20.6 0.0 4.5 4 0 0 4 4 4 3 CBS domain HAP1_N PF04849.13 KER29982.1 - 1.2e-75 254.6 20.7 7.1e-75 252.1 20.7 1.9 1 1 1 2 2 2 1 HAP1 N-terminal conserved region bZIP_1 PF00170.21 KER29982.1 - 0.014 15.5 17.8 0.054 13.6 1.3 3.9 4 0 0 4 4 4 0 bZIP transcription factor Milton PF12448.8 KER29982.1 - 0.029 14.5 0.1 0.029 14.5 0.1 3.1 2 1 0 2 2 2 0 Kinesin associated protein JIP_LZII PF16471.5 KER29982.1 - 0.11 12.7 12.8 0.53 10.5 0.9 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 KER29982.1 - 0.65 10.0 23.4 0.22 11.6 4.6 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 KER29982.1 - 0.78 10.2 11.1 0.99 9.9 0.5 3.3 3 0 0 3 3 3 0 Snapin/Pallidin ATG16 PF08614.11 KER29982.1 - 0.9 9.7 29.2 1.6 8.9 16.6 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HTH_8 PF02954.19 KER29982.1 - 0.98 9.3 3.7 0.95 9.3 0.7 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family TMF_TATA_bd PF12325.8 KER29982.1 - 1.5 9.1 25.7 0.88 9.8 4.7 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4472 PF14739.6 KER29982.1 - 3.2 8.5 14.8 0.19 12.4 3.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) Rho_Binding PF08912.11 KER29982.1 - 4.4 8.2 14.7 0.35 11.7 1.9 3.8 3 1 0 3 3 3 0 Rho Binding CCDC144C PF14915.6 KER29982.1 - 8.1 5.5 23.4 0.55 9.3 3.6 3.1 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region TSC22 PF01166.18 KER29982.1 - 8.5 6.8 16.0 6.5 7.2 1.2 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Putative_PNPOx PF01243.20 KER29983.1 - 4.1e-25 87.8 0.0 6.2e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KER29983.1 - 1.8e-18 66.4 1.0 4.1e-18 65.2 1.0 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KER29983.1 - 1.1e-06 29.1 0.0 2.4e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase RVT_1 PF00078.27 KER29984.1 - 4.8e-07 29.5 0.0 7.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSI PF01437.25 KER29984.1 - 0.00061 20.3 11.1 0.00061 20.3 11.1 2.7 3 0 0 3 3 3 1 Plexin repeat TMEM154 PF15102.6 KER29984.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.4 2 1 0 3 3 3 0 TMEM154 protein family DUF4656 PF15551.6 KER29985.1 - 0.061 12.8 0.9 0.088 12.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) CDC73_N PF16050.5 KER29992.1 - 6.3e-54 183.3 0.0 1.3e-39 136.3 0.0 3.2 2 1 1 3 3 3 3 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 KER29992.1 - 1.3e-31 109.4 0.2 3e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal Corona_NS4 PF03905.13 KER29993.1 - 0.047 13.7 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 Carboxyl_trans PF01039.22 KER29994.1 - 2.4e-82 277.2 0.0 1.5e-42 145.9 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain ssDBP_DBD PF18361.1 KER29994.1 - 0.043 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain Dynein_light PF01221.18 KER29995.1 - 3.9e-30 104.0 1.2 4.3e-30 103.9 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 NAD_binding_7 PF13241.6 KER29996.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3966 PF13110.6 KER29997.1 - 0.051 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) zf-C4 PF00105.18 KER29998.1 - 1.4e-11 44.7 2.9 3.6e-11 43.4 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RskA PF10099.9 KER29998.1 - 0.0079 16.5 0.5 0.018 15.3 0.5 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA zf-C4 PF00105.18 KER30000.1 - 1.6e-13 50.9 10.3 1.6e-13 50.9 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER30000.1 - 0.0026 17.4 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MEIOC PF15189.6 KER30005.1 - 0.0042 16.7 0.4 0.6 9.7 0.1 2.1 2 0 0 2 2 2 2 Meiosis-specific coiled-coil domain-containing protein MEIOC PPR_3 PF13812.6 KER30006.1 - 0.02 15.0 0.0 1.7 8.8 0.0 2.9 1 1 2 3 3 3 0 Pentatricopeptide repeat domain DNAP_B_exo_N PF08452.10 KER30007.1 - 0.49 9.9 6.3 7.3 6.1 0.6 2.4 2 0 0 2 2 2 0 DNA polymerase family B exonuclease domain, N-terminal TRAP_beta PF05753.14 KER30008.1 - 5.5e-37 126.9 0.1 6.6e-37 126.6 0.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 KER30008.1 - 0.0081 16.4 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 CARDB SieB PF14163.6 KER30008.1 - 0.25 10.9 1.2 1.4 8.4 0.0 2.5 2 1 1 3 3 3 0 Super-infection exclusion protein B ASH PF15780.5 KER30009.1 - 0.0086 16.3 0.1 2.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ASH PF15780.5 KER30010.1 - 7.1e-07 29.4 0.7 0.0042 17.2 0.0 3.7 3 1 1 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TB2_DP1_HVA22 PF03134.19 KER30014.1 - 2e-26 91.7 2.4 2e-26 91.7 2.4 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ammonium_transp PF00909.21 KER30014.1 - 0.0071 15.1 0.2 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4118 PF13493.6 KER30014.1 - 0.013 15.3 0.6 0.019 14.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) DUF2304 PF10066.9 KER30014.1 - 0.15 12.3 2.1 4.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) 7tm_1 PF00001.21 KER30015.1 - 3.8e-07 29.7 8.6 5.5e-07 29.2 8.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1604 PF07713.13 KER30018.1 - 2.6e-33 113.7 1.2 7.6e-33 112.2 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Epiglycanin_C PF14654.6 KER30019.1 - 0.14 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Usp PF00582.26 KER30021.1 - 3e-29 102.3 0.0 3.4e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Ank_2 PF12796.7 KER30022.1 - 5.1e-14 52.6 0.0 3.5e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER30022.1 - 8.2e-14 50.4 0.4 0.044 14.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KER30022.1 - 1.5e-10 41.4 3.9 0.00033 21.2 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER30022.1 - 4.5e-10 39.6 0.2 0.02 15.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KER30022.1 - 7.1e-08 32.6 0.6 0.23 12.0 0.0 4.3 4 1 0 4 4 4 2 Ankyrin repeat Ribosomal_S2 PF00318.20 KER30023.1 - 6.1e-27 94.3 1.3 3.6e-13 49.3 0.4 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Glycos_transf_2 PF00535.26 KER30024.1 - 2.2e-25 89.5 0.0 3.4e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 KER30024.1 - 1.1e-18 67.6 0.1 4.4e-18 65.8 0.1 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 KER30024.1 - 3.3e-07 29.9 0.0 8.1e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 KER30024.1 - 9.7e-05 22.4 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KER30024.1 - 0.00045 19.8 0.0 0.0033 17.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.6 KER30024.1 - 0.033 14.9 0.0 8.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like RhoGAP PF00620.27 KER30025.1 - 1.1e-24 87.0 6.1 7.4e-10 38.8 0.0 4.8 4 1 1 5 5 5 3 RhoGAP domain C2 PF00168.30 KER30025.1 - 9.9e-08 32.2 0.1 4.9e-07 30.0 0.1 2.2 1 1 1 2 2 2 1 C2 domain DOCK-C2 PF14429.6 KER30025.1 - 0.019 14.8 0.1 0.055 13.3 0.1 1.7 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins BRE1 PF08647.11 KER30025.1 - 0.029 14.4 4.1 0.7 10.0 0.1 3.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PH PF00169.29 KER30025.1 - 0.15 12.6 0.4 1.9 9.1 0.0 2.8 2 0 0 2 2 2 0 PH domain Asp PF00026.23 KER30027.1 - 0.0018 17.8 0.0 0.0026 17.2 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Ras PF00071.22 KER30032.1 - 2.5e-10 40.2 0.0 5.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KER30032.1 - 1.4e-08 34.9 0.0 4e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER30032.1 - 2.5e-05 23.8 0.0 0.004 16.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 KER30032.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KER30032.1 - 0.021 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase KH_1 PF00013.29 KER30034.1 - 1e-96 316.7 15.8 5.7e-15 54.9 0.0 15.6 16 0 0 16 16 16 10 KH domain SLS PF14611.6 KER30034.1 - 2.4e-10 40.6 13.6 0.007 16.2 0.0 8.7 6 2 3 10 10 10 2 Mitochondrial inner-membrane-bound regulator BMC PF00936.19 KER30034.1 - 0.0011 18.9 1.6 18 5.4 0.0 6.0 8 0 0 8 8 8 1 BMC domain KH_4 PF13083.6 KER30034.1 - 0.0027 17.6 3.8 11 6.0 0.0 5.8 5 1 1 6 6 6 1 KH domain MOEP19 PF16005.5 KER30034.1 - 0.019 14.9 0.4 15 5.7 0.0 4.6 5 0 0 5 5 5 0 KH-like RNA-binding domain DUF3090 PF11290.8 KER30034.1 - 0.081 12.7 2.2 24 4.7 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3090) DUF2017 PF09438.10 KER30034.1 - 0.13 12.1 1.9 0.33 10.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2017) TrkA_C PF02080.21 KER30034.1 - 0.15 11.9 0.5 46 4.0 0.1 5.1 5 0 0 5 5 5 0 TrkA-C domain FtsQ PF03799.15 KER30034.1 - 4.1 8.2 4.8 74 4.2 0.1 4.6 4 1 0 5 5 5 0 Cell division protein FtsQ Secretin_N PF03958.17 KER30034.1 - 4.7 7.7 11.1 30 5.1 0.1 7.1 10 1 0 10 10 10 0 Bacterial type II/III secretion system short domain AAA_33 PF13671.6 KER30036.1 - 7.8e-24 84.5 0.0 1.5e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 KER30036.1 - 1.6e-11 43.7 0.1 3.1e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain AAA_18 PF13238.6 KER30036.1 - 1e-05 26.1 0.1 2.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KER30036.1 - 0.0072 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KER30036.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KER30037.1 - 1.5e-33 116.3 0.0 7.3e-32 110.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30037.1 - 9.5e-15 54.6 0.0 6.7e-14 51.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER30037.1 - 0.004 16.5 0.0 0.0062 15.9 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER30037.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KER30037.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KER30037.1 - 0.23 11.3 0.1 1.1 9.2 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_1 PF00130.22 KER30039.1 - 2.4e-12 46.5 10.3 4.3e-12 45.7 10.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KER30039.1 - 0.028 14.7 4.8 0.056 13.8 4.8 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KER30039.1 - 0.035 14.0 8.4 0.11 12.4 8.4 1.8 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 KER30039.1 - 0.078 13.2 4.1 0.15 12.2 4.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_9 PF13901.6 KER30039.1 - 0.18 11.7 4.2 0.32 10.9 4.2 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD_2 PF13831.6 KER30039.1 - 1 9.0 7.3 0.048 13.2 0.8 2.1 2 0 0 2 2 2 0 PHD-finger EF-hand_1 PF00036.32 KER30044.1 - 3.6e-33 110.6 7.0 1.8e-07 30.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KER30044.1 - 7.5e-32 109.6 2.3 9.1e-15 54.9 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER30044.1 - 1.6e-25 86.8 3.9 2.3e-07 30.2 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KER30044.1 - 1.9e-24 85.2 6.3 7.6e-11 41.7 1.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KER30044.1 - 1e-23 81.7 11.2 4.3e-07 29.1 0.1 5.0 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 KER30044.1 - 1.6e-07 31.5 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KER30044.1 - 8e-06 26.2 0.0 0.0058 16.9 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER30044.1 - 9.1e-05 22.4 0.7 0.16 11.9 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KER30044.1 - 0.00096 19.3 3.6 0.36 11.1 0.1 3.3 2 2 2 4 4 4 3 Dockerin type I domain Caleosin PF05042.13 KER30044.1 - 0.004 17.1 0.5 1.3 8.9 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein EF-hand_11 PF08976.11 KER30044.1 - 0.0091 16.9 0.0 0.018 15.9 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 KER30044.1 - 0.1 11.1 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KER30044.1 - 0.14 12.5 0.1 1.2 9.6 0.0 2.2 2 1 1 3 3 3 0 EF-hand domain Excalibur PF05901.11 KER30044.1 - 3.7 8.2 4.9 57 4.4 0.0 3.4 4 0 0 4 4 4 0 Excalibur calcium-binding domain Peptidase_M16_C PF05193.21 KER30045.1 - 5.1e-38 130.9 0.0 1.5e-35 122.8 0.0 2.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KER30045.1 - 9.3e-26 90.6 0.0 4.2e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SAM_3 PF18016.1 KER30046.1 - 0.073 12.9 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4805 PF16063.5 KER30046.1 - 0.21 10.9 0.4 7.1 5.9 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4805) PurA PF04845.13 KER30047.1 - 5.4e-08 32.4 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein CaKB PF03185.15 KER30049.1 - 9.7e-11 41.7 1.7 0.0018 17.9 0.0 3.1 3 0 0 3 3 3 3 Calcium-activated potassium channel, beta subunit Pes-10 PF07149.11 KER30050.1 - 0.25 10.4 14.7 0.45 9.5 14.7 1.5 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 KER30050.1 - 0.62 8.2 37.7 0.85 7.8 37.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KER30050.1 - 1.3 8.3 36.0 1.9 7.7 36.0 1.1 1 0 0 1 1 1 0 BUD22 Cofilin_ADF PF00241.20 KER30056.1 - 4e-26 91.2 0.1 6.5e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RVT_1 PF00078.27 KER30056.1 - 4.3e-21 75.4 0.0 1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PET122 PF05476.11 KER30056.1 - 0.084 12.2 0.1 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 PET122 Arm PF00514.23 KER30057.1 - 1.1e-86 282.5 13.3 1.5e-12 47.1 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 KER30057.1 - 1.8e-23 81.8 0.0 3.1e-21 74.7 0.1 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KER30057.1 - 5.1e-23 81.1 3.9 1.7e-09 37.9 0.1 6.6 4 2 4 8 8 8 4 HEAT-like repeat IBB PF01749.20 KER30057.1 - 1.4e-21 76.7 0.0 1.6e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 KER30057.1 - 1.5e-20 73.4 0.3 1.6e-07 31.6 0.0 5.6 3 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KER30057.1 - 1.1e-17 62.6 6.6 0.00013 21.9 0.0 7.3 8 0 0 8 8 7 4 HEAT repeat Adaptin_N PF01602.20 KER30057.1 - 7.1e-08 31.5 0.0 2.8e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.13 KER30057.1 - 8.9e-07 28.6 0.4 0.067 12.6 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Cnd1 PF12717.7 KER30057.1 - 5.2e-06 26.6 0.0 3.1 7.8 0.0 3.9 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KER30057.1 - 0.0012 19.3 0.9 1.6e+02 3.4 0.0 6.4 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 KER30057.1 - 0.0085 16.2 0.0 15 5.8 0.0 3.6 2 1 3 5 5 5 0 V-ATPase subunit H ParcG PF10274.9 KER30057.1 - 0.0089 16.2 0.0 0.24 11.5 0.0 2.7 3 0 0 3 3 3 1 Parkin co-regulated protein RICTOR_V PF14668.6 KER30057.1 - 0.056 13.7 4.8 14 6.0 0.1 4.4 3 3 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Snurportin1 PF11538.8 KER30057.1 - 9.6 6.5 8.1 18 5.6 8.1 1.5 1 0 0 1 1 1 0 Snurportin1 FOP_dimer PF09398.10 KER30058.1 - 1.7e-08 34.6 0.1 8.1e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 KER30058.1 - 1.1e-05 24.3 0.3 1.7e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 LisH Asp PF00026.23 KER30059.1 - 8.5e-34 117.4 0.0 9.4e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER30059.1 - 6.1e-05 22.9 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PrmA PF06325.13 KER30060.1 - 3.4e-07 30.0 0.1 5.4e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KER30060.1 - 6.9e-06 26.7 0.0 2.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 KER30060.1 - 9.6e-05 22.3 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KER30060.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MTS PF05175.14 KER30060.1 - 0.00044 19.8 0.0 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KER30060.1 - 0.002 17.1 0.1 0.034 13.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 KER30060.1 - 0.0034 18.0 0.0 0.008 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KER30060.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KER30060.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KER30060.1 - 0.028 14.2 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KER30060.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KER30060.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KER30060.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FUN14 PF04930.15 KER30061.1 - 9e-07 29.2 4.3 1.5e-06 28.5 4.3 1.3 1 0 0 1 1 1 1 FUN14 family Aph-1 PF06105.12 KER30061.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Aph-1 protein Ribosom_S12_S23 PF00164.25 KER30062.1 - 3.8e-26 90.9 1.0 4.8e-26 90.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyltransferase PF01553.21 KER30063.1 - 1.1e-21 76.9 0.0 8.3e-21 74.0 0.0 2.0 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KER30063.1 - 7.4e-08 32.4 0.2 1.8e-07 31.2 0.2 1.7 1 1 0 1 1 1 1 Acyltransferase C-terminus Arm PF00514.23 KER30068.1 - 0.11 12.6 0.8 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat GLTP PF08718.11 KER30068.1 - 0.12 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) VEGFR-2_TMD PF17988.1 KER30070.1 - 0.23 11.0 0.7 0.46 10.0 0.2 1.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain VEGFR-2_TMD PF17988.1 KER30072.1 - 0.016 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain TDP43_N PF18694.1 KER30073.1 - 1.2e-28 98.7 0.0 2.3e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 KER30073.1 - 1.5e-23 82.4 0.0 8.5e-11 41.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER30073.1 - 5.5e-05 23.2 0.2 0.02 15.0 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KER30073.1 - 6.6e-05 22.8 0.1 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 KER30073.1 - 0.019 14.9 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 RL domain Nup35_RRM PF05172.13 KER30073.1 - 0.049 13.6 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MCM PF00493.23 KER30074.1 - 9.4e-94 312.7 0.2 1.3e-93 312.2 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain GBP PF02263.19 KER30074.1 - 4.2e-52 177.0 0.0 3.5e-27 95.3 0.0 2.2 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain Mg_chelatase PF01078.21 KER30074.1 - 7.2e-05 22.3 0.0 0.00034 20.0 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2304 PF10066.9 KER30074.1 - 0.16 12.2 1.7 0.34 11.2 1.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) zf-UBR PF02207.20 KER30075.1 - 4.4e-18 65.2 13.2 4.4e-18 65.2 13.2 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KER30075.1 - 1.2e-08 34.6 0.2 3.3e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS AA_permease_C PF13906.6 KER30076.1 - 0.054 13.6 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 C-terminus of AA_permease RT_RNaseH PF17917.1 KER30077.1 - 9.5e-07 29.1 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER30077.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RhoGAP PF00620.27 KER30078.1 - 7.6e-29 100.5 0.4 1.9e-17 63.5 0.1 2.7 3 0 0 3 3 3 2 RhoGAP domain Transcrip_reg PF01709.20 KER30079.1 - 2.2e-41 141.8 0.0 2.6e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator AbbA_antirepres PF14156.6 KER30079.1 - 0.069 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Antirepressor AbbA Pkinase PF00069.25 KER30080.1 - 3.5e-62 210.2 0.0 6.2e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30080.1 - 2.4e-31 109.0 0.0 3.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KER30080.1 - 7.7e-08 32.1 6.5 1.8e-07 30.9 6.5 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.24 KER30080.1 - 1.4e-07 31.3 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 KER30080.1 - 0.00019 20.8 0.0 0.0012 18.2 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KER30080.1 - 0.0045 16.0 0.2 0.011 14.7 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KER30080.1 - 0.022 14.4 0.1 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KER30080.1 - 0.07 13.0 0.0 0.24 11.3 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 KER30081.1 - 9.2e-06 26.3 5.2 1.2e-05 25.9 5.2 1.2 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF423 PF04241.15 KER30082.1 - 6.4e-23 80.8 0.3 1.2e-22 79.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF1304 PF06993.12 KER30082.1 - 0.075 13.0 0.8 0.14 12.1 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1304) Nucleoside_tran PF01733.18 KER30083.1 - 1.7e-34 119.6 0.2 2.3e-34 119.2 0.2 1.1 1 0 0 1 1 1 1 Nucleoside transporter Exo_endo_phos_2 PF14529.6 KER30083.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ENTH PF01417.20 KER30086.1 - 7.3e-45 152.1 0.1 1.3e-44 151.2 0.1 1.4 1 0 0 1 1 1 1 ENTH domain Lactamase_B_2 PF12706.7 KER30086.1 - 3.2e-12 46.4 0.3 2.5e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KER30086.1 - 2.8e-06 27.5 0.1 6.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ANTH PF07651.16 KER30086.1 - 1.3e-05 24.3 0.1 2.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 KER30086.1 - 7.3 6.8 6.0 1.5 8.9 1.9 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Nucleoside_tran PF01733.18 KER30089.1 - 2.2e-46 158.7 1.5 2.4e-46 158.5 1.5 1.0 1 0 0 1 1 1 1 Nucleoside transporter DUF1772 PF08592.11 KER30089.1 - 0.00031 21.1 4.9 0.021 15.1 1.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Cation_ATPase_C PF00689.21 KER30089.1 - 0.0027 17.5 1.6 0.0027 17.5 1.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus DC_STAMP PF07782.13 KER30089.1 - 0.006 16.4 0.1 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 DC-STAMP-like protein Picorna_P3A PF06363.11 KER30089.1 - 0.17 11.8 0.6 0.27 11.1 0.1 1.6 2 0 0 2 2 2 0 Picornaviridae P3A protein PARP PF00644.20 KER30091.1 - 1.1e-43 149.2 0.0 2.6e-43 147.9 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KER30091.1 - 1.5e-37 128.7 0.8 2e-37 128.3 0.1 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain tRNA-synt_2c PF01411.19 KER30092.1 - 5.4e-98 328.9 0.0 1.9e-77 261.1 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KER30092.1 - 7.7e-05 22.7 0.2 0.00023 21.2 0.1 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain Crp PF00325.20 KER30093.1 - 0.1 12.2 0.2 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family DUF4761 PF15958.5 KER30093.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) HTH_46 PF15977.5 KER30093.1 - 0.26 11.3 1.4 0.77 9.8 0.1 1.9 1 1 1 2 2 2 0 Winged helix-turn-helix DNA binding Ank_2 PF12796.7 KER30097.1 - 1.6e-10 41.4 0.1 2.6e-09 37.5 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER30097.1 - 1.2e-09 38.5 0.1 7.1e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER30097.1 - 3.9e-08 32.9 0.1 0.24 12.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KER30097.1 - 1e-07 32.1 0.1 2.7e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KER30097.1 - 1.5e-05 25.2 1.1 0.32 11.5 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat PDH_E1_M PF17831.1 KER30097.1 - 0.057 12.9 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain ACT PF01842.25 KER30097.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 ACT domain RVT_1 PF00078.27 KER30098.1 - 3.1e-25 89.0 0.0 1.4e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER30098.1 - 1.7e-08 34.2 1.0 3.1e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Cyt-b5 PF00173.28 KER30099.1 - 1.2e-09 38.2 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CD34_antigen PF06365.12 KER30099.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4424 PF14415.6 KER30099.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Asparaginase_2 PF01112.18 KER30101.1 - 1.1e-138 461.4 4.9 2.4e-66 223.8 0.0 4.4 5 0 0 5 5 5 3 Asparaginase DEAD PF00270.29 KER30101.1 - 1.2e-50 171.7 0.0 2.8e-50 170.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER30101.1 - 1.7e-29 102.4 0.0 3.2e-28 98.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KER30101.1 - 0.078 12.3 0.0 0.078 12.3 0.0 3.3 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Pkinase PF00069.25 KER30102.1 - 5.3e-78 262.0 0.0 7e-45 153.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KER30102.1 - 1.1e-33 116.6 0.0 7.7e-26 90.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Haspin_kinase PF12330.8 KER30102.1 - 9.2e-05 21.5 0.1 0.00022 20.3 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KER30102.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KER30102.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KER30102.1 - 0.06 12.6 0.3 0.61 9.3 0.0 2.6 4 0 0 4 4 4 0 Kinase-like DUF4705 PF15788.5 KER30102.1 - 0.071 13.4 0.5 61 4.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4705) DUF3496 PF12001.8 KER30103.1 - 0.033 14.6 3.3 0.038 14.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF4407 PF14362.6 KER30103.1 - 0.048 13.0 1.9 0.057 12.8 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1818 PF08848.11 KER30103.1 - 0.1 12.7 2.4 0.11 12.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) YAcAr PF10686.9 KER30103.1 - 0.11 12.4 0.1 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family BRCA-2_OB1 PF09103.10 KER30103.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Fusion_gly PF00523.18 KER30103.1 - 0.15 10.3 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Arrestin_C PF02752.22 KER30105.1 - 0.00012 22.6 11.7 0.00012 22.6 11.7 3.0 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KER30105.1 - 0.088 12.9 0.1 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF2452 PF10504.9 KER30106.1 - 8.6e-48 161.7 0.1 1.3e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) PHD PF00628.29 KER30107.1 - 0.00034 20.4 6.2 0.00076 19.3 6.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KER30107.1 - 0.13 12.2 2.9 0.33 10.9 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_Oberon PF07227.11 KER30107.1 - 0.26 11.2 6.1 0.43 10.5 6.1 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein C1_2 PF03107.16 KER30107.1 - 4.1 7.8 8.5 8.8 6.7 5.5 2.6 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 KER30107.1 - 5.4 7.0 7.8 1.5 8.7 3.8 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNARE PF05739.19 KER30108.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 SNARE domain MFS_2 PF13347.6 KER30108.1 - 0.019 13.5 0.0 0.023 13.3 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein Homeodomain PF00046.29 KER30109.1 - 1.1e-07 31.6 0.2 6.8e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 Homeodomain DUF883 PF05957.13 KER30110.1 - 0.00071 20.1 2.9 0.00071 20.1 2.9 6.0 3 3 4 7 7 7 1 Bacterial protein of unknown function (DUF883) FIN1 PF17300.2 KER30110.1 - 0.0025 17.3 1.1 0.0025 17.3 1.1 4.7 2 2 1 4 4 4 1 Filaments in between nuclei protein-1 DUF357 PF04010.13 KER30110.1 - 0.19 11.8 1.2 1.1 9.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) LSM PF01423.22 KER30112.1 - 1.2e-09 37.7 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KER30112.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Myb_DNA-binding PF00249.31 KER30113.1 - 3.3e-28 97.6 0.0 3.5e-10 39.9 0.1 5.0 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KER30113.1 - 1.6e-18 66.7 0.0 8.9e-10 38.7 0.0 4.7 2 1 3 5 5 5 4 Myb-like DNA-binding domain SLIDE PF09111.10 KER30113.1 - 0.035 14.1 0.0 25 5.0 0.0 3.6 4 0 0 4 4 4 0 SLIDE PAN_1 PF00024.26 KER30115.1 - 0.00011 22.0 0.3 0.00013 21.9 0.3 1.1 1 0 0 1 1 1 1 PAN domain Stimulus_sens_1 PF13756.6 KER30116.1 - 0.18 12.4 0.0 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Stimulus-sensing domain HEAT PF02985.22 KER30117.1 - 8.7e-21 72.2 12.8 2.5e-06 27.3 0.0 9.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KER30117.1 - 2.8e-20 72.4 12.0 1.7e-12 47.6 0.1 6.9 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 KER30117.1 - 5.5e-10 39.5 2.5 0.00021 21.6 0.0 6.5 4 2 2 7 7 7 3 HEAT repeats IBN_N PF03810.19 KER30117.1 - 3.3e-09 36.5 0.6 8.1e-08 32.1 0.1 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KER30117.1 - 1.3e-08 33.9 1.3 0.016 13.8 0.0 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Arm PF00514.23 KER30117.1 - 7.4e-08 32.2 8.4 0.041 13.9 0.0 6.1 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KER30117.1 - 1.6e-05 25.0 3.7 0.13 12.3 0.0 5.3 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KER30117.1 - 5e-05 23.8 0.6 0.38 11.4 0.1 4.4 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 KER30117.1 - 0.00024 20.4 0.1 0.0031 16.8 0.0 2.6 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 KER30117.1 - 0.0012 18.4 2.2 3.4 7.2 0.1 4.3 4 1 1 5 5 5 2 CLASP N terminal Proteasom_PSMB PF10508.9 KER30117.1 - 0.015 13.8 0.3 0.14 10.6 0.0 2.3 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit IMP2_C PF18591.1 KER30118.1 - 0.06 13.2 1.1 0.11 12.4 0.1 2.0 3 0 0 3 3 3 0 Immune Mapped Protein 2 (IMP2) C-terminal domain Glyco_hydro_47 PF01532.20 KER30121.1 - 1.1e-135 453.1 0.0 1.4e-135 452.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Arf PF00025.21 KER30122.1 - 1.7e-54 183.9 0.0 1.9e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KER30122.1 - 5.3e-15 55.3 0.0 6.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KER30122.1 - 3.5e-13 49.8 0.0 4.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KER30122.1 - 1.7e-11 44.0 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KER30122.1 - 5.7e-11 42.2 1.8 1.7e-06 27.5 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 KER30122.1 - 4.3e-09 36.5 0.0 7.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KER30122.1 - 1.2e-08 34.7 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KER30122.1 - 3.8e-06 26.6 0.0 0.0039 16.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KER30122.1 - 1.1e-05 25.7 0.2 0.00031 21.0 0.3 2.6 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 KER30122.1 - 0.0018 17.8 0.6 0.0096 15.5 0.5 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KER30122.1 - 0.0018 18.8 0.1 0.0028 18.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KER30122.1 - 0.0073 16.4 0.4 4.3 7.4 0.1 2.2 2 0 0 2 2 2 2 Dynamin family ATP_bind_1 PF03029.17 KER30122.1 - 0.0094 15.8 0.0 0.25 11.1 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KER30122.1 - 0.055 13.4 0.1 12 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 KER30122.1 - 0.076 12.7 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KER30122.1 - 0.083 12.6 0.4 0.28 10.9 0.4 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KER30122.1 - 0.1 12.3 0.5 0.22 11.2 0.5 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3364 PF11844.8 KER30122.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Thymidylate_kin PF02223.17 KER30122.1 - 0.16 11.6 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase SH2 PF00017.24 KER30124.1 - 4.2e-16 58.8 0.0 8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RT_RNaseH PF17917.1 KER30126.1 - 6.7e-07 29.6 0.0 3.2e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RasGEF PF00617.19 KER30128.1 - 7.7e-45 153.3 0.0 1.3e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KER30128.1 - 5.1e-12 46.0 1.1 3e-09 37.1 0.7 3.2 2 1 0 2 2 2 1 RasGEF N-terminal motif cNMP_binding PF00027.29 KER30128.1 - 1.4e-11 44.3 0.0 1e-07 31.9 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ_6 PF17820.1 KER30128.1 - 0.0034 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ephrin_rec_like PF07699.13 KER30132.1 - 5.3e-05 22.9 4.8 0.00014 21.6 4.8 1.7 1 0 0 1 1 1 1 Putative ephrin-receptor like NCD3G PF07562.14 KER30132.1 - 0.0032 17.4 1.6 0.0032 17.4 1.6 2.4 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR CTV_P6 PF06706.11 KER30132.1 - 0.1 12.3 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Y_phosphatase PF00102.27 KER30137.1 - 6.3e-47 160.1 0.1 7e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KER30137.1 - 0.00049 19.9 0.0 0.00092 19.0 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER30137.1 - 0.001 19.1 0.0 0.0011 19.0 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 KER30137.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KER30137.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Tagatose_6_P_K PF08013.11 KER30138.1 - 0.091 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase DTW PF03942.15 KER30141.1 - 8.8e-37 126.7 0.1 1e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 DTW domain SWIRM-assoc_2 PF16496.5 KER30142.1 - 5.9e-95 318.6 0.0 5.9e-95 318.6 0.0 2.6 3 0 0 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 KER30142.1 - 4.8e-32 110.1 0.0 1.3e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KER30142.1 - 7e-26 90.0 14.7 7e-26 90.0 14.7 2.4 1 1 1 2 2 2 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 KER30142.1 - 2.2e-21 75.9 1.2 2.2e-21 75.9 1.2 2.8 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 KER30142.1 - 1.2e-12 47.8 0.3 3.4e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KER30142.1 - 2e-07 31.1 0.2 9.5e-07 29.0 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Exo_endo_phos_2 PF14529.6 KER30143.1 - 0.0018 18.1 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Peptidase_C93 PF06035.11 KER30143.1 - 0.15 11.8 0.1 7 6.4 0.0 2.0 1 1 1 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP His_Phos_1 PF00300.22 KER30145.1 - 4.8e-17 62.3 0.2 1.4e-08 34.6 0.1 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3808 PF10300.9 KER30146.1 - 1.7e-43 149.1 2.2 1.7e-43 149.1 2.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KER30146.1 - 1.7e-07 31.4 0.8 0.0022 18.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER30146.1 - 4.8e-05 23.2 0.9 1.3 9.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER30146.1 - 0.00018 22.0 0.4 1.3 9.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER30146.1 - 0.00039 21.0 2.4 1.4 9.6 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER30146.1 - 0.0058 16.4 0.6 7.1 6.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER30146.1 - 0.0067 15.8 2.9 2.7 7.3 0.0 2.9 3 0 0 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 KER30146.1 - 0.018 15.2 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KER30146.1 - 0.054 14.1 0.0 9.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KER30146.1 - 0.073 12.8 0.0 7.1 6.4 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 KER30146.1 - 0.099 13.1 0.1 6.1 7.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TACC_C PF05010.14 KER30146.1 - 0.1 12.4 0.8 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RPN7 PF10602.9 KER30146.1 - 0.12 12.1 0.5 12 5.5 0.0 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 KER30146.1 - 0.12 12.6 7.8 9.7 6.5 0.8 3.9 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER30146.1 - 0.2 12.6 4.3 4.1 8.5 0.0 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 KER30147.1 - 6.4e-54 183.5 2.3 1e-53 182.8 2.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Radical_SAM_C PF16199.5 KER30148.1 - 3.4e-32 110.3 0.0 7.7e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KER30148.1 - 2.9e-20 73.3 0.7 2.1e-19 70.5 0.2 2.3 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KER30148.1 - 1.3e-08 35.1 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER30148.1 - 2.4e-05 24.3 0.0 7.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KER30148.1 - 0.02 15.3 0.1 0.041 14.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER30148.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein MitoNEET_N PF10660.9 KER30149.1 - 4.1e-18 65.2 0.0 5.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 KER30149.1 - 1.7e-08 34.5 4.0 3.1e-08 33.7 4.0 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Trypsin PF00089.26 KER30150.1 - 3e-60 203.8 0.0 3.1e-59 200.5 0.0 1.9 1 1 0 1 1 1 1 Trypsin SBF2 PF12335.8 KER30151.1 - 5.9e-06 26.1 1.9 5.9e-06 26.1 1.9 1.7 1 1 1 2 2 2 1 Myotubularin protein CRAL_TRIO PF00650.20 KER30152.1 - 3.1e-24 85.5 0.0 6.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KER30152.1 - 6.9e-07 29.4 0.1 1.8e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KER30152.1 - 8.1e-07 29.3 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GIY-YIG PF01541.24 KER30152.1 - 0.00067 19.9 0.3 0.0014 18.8 0.3 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Flavokinase PF01687.17 KER30153.1 - 1.5e-33 115.4 0.0 1.9e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Barstar PF01337.18 KER30153.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Ras PF00071.22 KER30156.1 - 2.3e-60 202.9 0.1 2.9e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER30156.1 - 3.5e-33 114.4 0.1 5e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER30156.1 - 6e-12 45.4 0.0 8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER30156.1 - 5.5e-05 23.2 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER30156.1 - 0.0011 18.5 0.0 0.0053 16.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER30156.1 - 0.0025 17.7 0.0 0.24 11.3 0.0 2.5 1 1 2 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 KER30156.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KER30156.1 - 0.037 14.3 0.0 0.18 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain TetR_C_16 PF17920.1 KER30156.1 - 0.043 14.1 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DAP3 PF10236.9 KER30156.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3067 PF11267.8 KER30156.1 - 0.16 12.6 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) Med11 PF10280.9 KER30157.1 - 4.1e-10 40.2 0.1 5.1e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Sec34 PF04136.15 KER30157.1 - 0.014 15.3 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Sec34-like family SieB PF14163.6 KER30157.1 - 0.042 13.4 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B BLOC1_2 PF10046.9 KER30157.1 - 0.08 13.3 1.0 3.2 8.1 0.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RhoGAP PF00620.27 KER30158.1 - 1.6e-42 144.9 0.0 5.8e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KER30158.1 - 6.4e-39 133.3 0.3 1.2e-38 132.4 0.3 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KER30158.1 - 2.3e-09 37.2 0.1 6.7e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain Abhydrolase_2 PF02230.16 KER30160.1 - 1e-73 247.8 0.0 1.2e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KER30160.1 - 8.6e-06 25.2 0.0 0.092 12.0 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KER30160.1 - 1.9e-05 25.4 0.3 2.6e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KER30160.1 - 4.9e-05 23.1 0.0 5.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 KER30160.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 KER30160.1 - 0.0018 18.0 0.0 0.011 15.4 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 KER30160.1 - 0.002 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 KER30160.1 - 0.014 14.8 0.7 2.6 7.4 0.3 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KER30160.1 - 0.019 14.5 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KER30160.1 - 0.023 14.4 0.1 0.074 12.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KER30160.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Smr PF01713.21 KER30160.1 - 0.037 14.4 0.0 7.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Smr domain Lipase_3 PF01764.25 KER30160.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ADK PF00406.22 KER30161.1 - 7.3e-23 81.3 0.0 3.7e-12 46.6 0.0 5.1 5 0 0 5 5 4 4 Adenylate kinase AAA_17 PF13207.6 KER30161.1 - 4.5e-14 53.0 16.2 0.0001 22.7 0.0 8.1 9 0 0 9 9 7 4 AAA domain FAP206 PF12018.8 KER30161.1 - 1.7e-11 44.2 9.1 0.00023 20.8 0.0 5.7 4 2 0 5 5 5 3 Domain of unknown function AAA PF00004.29 KER30161.1 - 3.9e-11 43.5 1.0 0.0016 18.8 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) YHS PF04945.13 KER30161.1 - 1.2e-10 41.3 0.2 0.0003 20.8 0.0 4.5 4 0 0 4 4 4 2 YHS domain AAA_22 PF13401.6 KER30161.1 - 3.8e-08 33.7 0.1 0.37 11.1 0.0 4.0 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 KER30161.1 - 1.1e-07 32.1 0.3 0.21 11.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 KER30161.1 - 1e-06 29.3 6.9 0.11 13.1 0.0 4.9 5 0 0 5 5 3 2 AAA domain AAA_16 PF13191.6 KER30161.1 - 5.5e-06 26.9 1.7 0.64 10.4 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_28 PF13521.6 KER30161.1 - 8e-06 26.2 13.0 0.00026 21.3 0.0 5.4 6 0 0 6 6 4 1 AAA domain SKI PF01202.22 KER30161.1 - 1.2e-05 25.5 2.6 0.24 11.5 0.2 4.1 4 0 0 4 4 4 2 Shikimate kinase MMR_HSR1 PF01926.23 KER30161.1 - 0.0001 22.4 0.0 0.22 11.6 0.0 3.4 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KER30161.1 - 0.0003 20.6 0.7 0.16 11.7 0.0 3.1 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 KER30161.1 - 0.00043 20.8 0.7 11 6.5 0.0 4.1 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.22 KER30161.1 - 0.0012 19.2 0.0 3.8 7.9 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_5 PF07728.14 KER30161.1 - 0.002 18.1 0.1 0.7 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KER30161.1 - 0.0058 16.0 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KER30161.1 - 0.008 16.2 0.0 2.2 8.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KER30161.1 - 0.011 15.7 0.1 5 7.0 0.0 3.5 4 0 0 4 4 4 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KER30161.1 - 0.014 14.6 0.0 0.32 10.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Hydin_ADK PF17213.3 KER30161.1 - 0.033 14.5 0.1 0.033 14.5 0.1 3.4 4 0 0 4 4 2 0 Hydin Adenylate kinase-like domain MutS_III PF05192.18 KER30161.1 - 0.051 13.8 4.1 2.4 8.3 4.7 2.8 2 1 0 2 2 2 0 MutS domain III Roc PF08477.13 KER30161.1 - 0.052 13.8 0.0 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KER30161.1 - 0.071 13.2 3.2 65 3.5 0.0 4.4 4 0 0 4 4 4 0 Dynamin family Cytidylate_kin PF02224.18 KER30161.1 - 0.076 12.7 0.4 9 6.0 0.5 3.5 3 1 1 4 4 4 0 Cytidylate kinase DAO_C PF16901.5 KER30161.1 - 0.091 12.6 0.1 0.32 10.9 0.1 1.9 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase AAA_25 PF13481.6 KER30161.1 - 0.11 12.1 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KER30161.1 - 0.12 12.1 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KER30161.1 - 0.12 12.2 0.1 27 4.7 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_7 PF12775.7 KER30161.1 - 0.13 11.8 0.0 12 5.4 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region FliG_M PF14841.6 KER30161.1 - 0.16 12.2 2.7 0.41 10.9 2.7 1.7 1 0 0 1 1 1 0 FliG middle domain PA26 PF04636.13 KER30162.1 - 7.5e-103 344.8 0.0 2.7e-88 296.8 0.0 2.1 2 0 0 2 2 2 2 PA26 p53-induced protein (sestrin) Moricin PF06451.11 KER30162.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Moricin EF-hand_7 PF13499.6 KER30163.1 - 1.5e-10 41.4 0.1 4.7e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KER30163.1 - 7.2e-10 37.9 0.3 0.00031 20.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 KER30163.1 - 2.8e-09 35.9 0.4 8.1e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER30163.1 - 1.1e-08 34.3 0.1 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KER30163.1 - 1.6e-06 27.9 0.5 0.01 15.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair GAS2 PF02187.17 KER30164.1 - 8.5e-24 83.4 0.9 1.7e-23 82.5 0.9 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 KER30164.1 - 2.3e-07 30.9 0.0 8.5e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Nup96 PF12110.8 KER30165.1 - 3.9e-88 295.3 0.0 5.8e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KER30165.1 - 4.5e-46 156.7 0.0 7.8e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KER30165.1 - 2.9e-10 40.9 211.2 0.00026 21.8 27.6 9.5 4 1 6 10 10 10 7 Nucleoporin FG repeat region Phospholip_A2_1 PF00068.19 KER30166.1 - 1.4 9.4 6.2 18 5.8 0.4 2.5 2 0 0 2 2 2 0 Phospholipase A2 Ric8 PF10165.9 KER30167.1 - 2.3e-86 290.7 5.2 5.4e-67 226.8 0.2 2.2 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn LEM PF03020.15 KER30167.1 - 0.086 12.4 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 LEM domain MMS22L_C PF14911.6 KER30168.1 - 3.5e-07 29.6 4.1 5.5e-07 29.0 0.2 2.9 3 1 0 3 3 3 1 S-phase genomic integrity recombination mediator, C-terminal MMS22L_N PF14910.6 KER30168.1 - 0.00011 20.8 0.2 0.00011 20.8 0.2 2.1 2 0 0 2 2 2 1 S-phase genomic integrity recombination mediator, N-terminal Histone PF00125.24 KER30170.1 - 7.4e-54 181.6 1.5 8.3e-54 181.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KER30170.1 - 7.4e-05 22.8 0.2 0.00016 21.8 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KER30170.1 - 8.5e-05 23.2 1.6 0.0001 22.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KER30170.1 - 0.00046 20.5 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KER30170.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bestrophin PF01062.21 KER30171.1 - 3.2e-51 174.5 0.7 2.4e-27 96.1 0.0 2.2 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel 7TM_GPCR_Srh PF10318.9 KER30171.1 - 0.027 13.5 0.4 0.027 13.5 0.4 1.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh Tubulin PF00091.25 KER30172.1 - 9e-58 195.7 0.0 1.6e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER30172.1 - 1.4e-41 141.6 0.2 2.1e-41 141.0 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER30172.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 KER30174.1 - 3.6e-71 239.4 0.0 5.7e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER30174.1 - 8.3e-44 148.8 0.1 1.3e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER30174.1 - 1.9e-05 24.9 0.0 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KER30174.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KER30174.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Tubulin like MOLO1 PF17175.4 KER30176.1 - 3.3e-09 36.9 0.1 7e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Pkinase PF00069.25 KER30178.1 - 7.8e-29 100.8 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30178.1 - 9.9e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mucin PF01456.17 KER30180.1 - 0.59 10.1 3.1 1 9.3 3.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2048 PF09752.9 KER30182.1 - 3.4e-87 292.8 0.0 5.7e-86 288.8 0.0 2.1 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 KER30182.1 - 1.9e-05 25.4 4.7 0.00048 20.8 4.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KER30182.1 - 0.05 13.2 0.0 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 KER30182.1 - 0.071 12.6 0.1 0.87 9.0 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3677 PF12432.8 KER30183.1 - 1e-10 41.8 0.0 3.9e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) HEAT PF02985.22 KER30183.1 - 0.073 13.4 0.2 1.3e+02 3.2 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat DUF2838 PF10998.8 KER30185.1 - 1.8e-19 70.0 13.2 1.8e-19 70.0 13.2 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) bZIP_2 PF07716.15 KER30186.1 - 0.0077 16.3 2.4 0.019 15.0 2.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KER30186.1 - 0.51 10.5 7.0 0.22 11.6 4.0 1.8 2 0 0 2 2 2 0 bZIP transcription factor Metallothio_PEC PF02068.16 KER30186.1 - 4.3 7.8 15.8 2.5 8.5 11.7 2.7 2 0 0 2 2 2 0 Plant PEC family metallothionein OCRE PF17780.1 KER30187.1 - 2.6e-16 59.4 13.7 3.2e-16 59.1 12.4 1.9 2 0 0 2 2 2 1 OCRE domain FHA PF00498.26 KER30187.1 - 6.5e-15 55.2 0.0 1.8e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain G-patch PF01585.23 KER30187.1 - 6.9e-14 51.5 0.2 1.2e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KER30187.1 - 1.1e-07 31.9 0.2 2.4e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 G-patch domain Angiomotin_C PF12240.8 KER30187.1 - 0.0058 16.2 0.5 0.015 14.8 0.5 1.7 1 0 0 1 1 1 1 Angiomotin C terminal Tropomyosin_1 PF12718.7 KER30187.1 - 0.014 15.5 3.5 0.026 14.7 3.5 1.3 1 0 0 1 1 1 0 Tropomyosin like DivIC PF04977.15 KER30187.1 - 0.25 11.2 2.8 0.51 10.1 2.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Spc7_N PF15402.6 KER30187.1 - 1.3 7.2 16.7 1.9 6.6 16.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Lyase_aromatic PF00221.19 KER30189.1 - 1.8e-186 620.4 1.0 2.1e-186 620.1 1.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Par3_HAL_N_term PF12053.8 KER30189.1 - 0.15 12.3 0.1 1.3 9.3 0.1 2.6 2 1 0 2 2 2 0 N-terminal of Par3 and HAL proteins RF-1 PF00472.20 KER30191.1 - 2.6e-21 75.7 0.5 3.4e-21 75.4 0.5 1.1 1 0 0 1 1 1 1 RF-1 domain Rab5-bind PF09311.11 KER30193.1 - 8.4e-48 163.3 34.8 8.4e-48 163.3 34.8 2.1 2 0 0 2 2 2 1 Rabaptin-like protein Rabaptin PF03528.15 KER30193.1 - 2.8e-08 32.9 1.6 2.8e-08 32.9 1.6 3.1 2 1 1 3 3 3 1 Rabaptin PKcGMP_CC PF16808.5 KER30193.1 - 8.9 6.3 9.9 59 3.6 0.2 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Amidohydro_1 PF01979.20 KER30194.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KER30194.1 - 2.2e-06 27.4 0.0 3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KER30196.1 - 0.0045 16.5 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family DUF1981 PF09324.10 KER30197.1 - 8.4e-10 38.4 0.0 3.8e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7 PF01369.20 KER30197.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain SAM_1 PF00536.30 KER30198.1 - 8.1e-27 93.5 0.7 2.7e-10 40.5 0.1 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER30198.1 - 2.5e-24 85.2 1.0 1.7e-10 40.8 0.1 4.3 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) UPF0121 PF03661.13 KER30199.1 - 6.9e-73 245.0 6.1 3.7e-43 147.7 2.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) MASE5 PF17178.4 KER30199.1 - 0.066 13.0 1.1 1 9.1 0.1 2.1 2 0 0 2 2 2 0 Membrane-associated sensor VRR_NUC PF08774.11 KER30200.1 - 7.3e-24 83.9 0.0 1.7e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain DUF4681 PF15732.5 KER30201.1 - 0.0066 16.7 0.0 0.0078 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4681) eIF3_subunit PF08597.10 KER30202.1 - 1.7e-39 136.2 12.7 1.8e-39 136.1 12.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pet20 PF08692.10 KER30202.1 - 0.12 13.1 0.4 0.42 11.3 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 G_path_suppress PF15991.5 KER30202.1 - 3.4 7.7 10.9 5.4 7.1 10.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor TMF_TATA_bd PF12325.8 KER30203.1 - 0.00017 21.8 11.9 0.00017 21.8 11.9 8.9 7 1 2 9 9 9 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KER30203.1 - 0.00079 20.0 21.8 0.00079 20.0 21.8 7.5 5 4 1 6 6 6 1 Apg6 coiled-coil region Flg_hook PF02120.16 KER30203.1 - 0.18 11.7 10.3 0.032 14.1 1.5 4.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK TPR_MLP1_2 PF07926.12 KER30203.1 - 0.19 11.8 0.1 0.19 11.8 0.1 8.1 7 1 1 9 9 9 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KER30204.1 - 0.84 9.8 44.9 0.082 13.1 0.3 6.8 6 2 1 8 8 8 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KER30205.1 - 0.067 13.2 5.7 7 6.7 0.1 4.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1664) IL11 PF07400.11 KER30205.1 - 0.38 10.4 2.9 1.9 8.1 0.1 3.7 3 0 0 3 3 3 0 Interleukin 11 LSDAT_euk PF18139.1 KER30209.1 - 8.7e-38 130.2 0.3 7.8e-22 77.9 0.0 3.3 2 1 1 3 3 3 3 SLOG in TRPM LSDAT_prok PF18171.1 KER30209.1 - 1.4e-10 40.8 0.1 0.0032 16.8 0.0 3.3 3 0 0 3 3 3 3 SLOG in TRPM, prokaryote Metallophos PF00149.28 KER30210.1 - 3.4e-40 138.7 0.0 4.5e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER30210.1 - 0.00039 20.8 0.5 0.00089 19.7 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KER30210.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Peptidase_C54 PF03416.19 KER30211.1 - 6e-18 65.2 0.1 9.8e-10 38.3 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 NUDIX PF00293.28 KER30212.1 - 1.3e-08 35.0 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain TPT PF03151.16 KER30213.1 - 6.5e-10 38.8 10.5 8.4e-10 38.5 10.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family LSM PF01423.22 KER30213.1 - 3.2e-07 29.9 0.0 5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain EamA PF00892.20 KER30213.1 - 7.7e-06 26.1 21.8 0.00026 21.2 16.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family CwfJ_C_1 PF04677.15 KER30215.1 - 1.2e-30 105.8 0.0 2.6e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KER30215.1 - 9e-10 39.3 0.0 2.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 AAA PF00004.29 KER30216.1 - 4.2e-43 146.9 0.0 8.7e-43 145.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER30216.1 - 5.1e-13 48.6 0.0 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KER30216.1 - 4.9e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KER30216.1 - 1.2e-06 28.6 0.0 4.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KER30216.1 - 2.2e-06 28.1 0.3 6.8e-05 23.3 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KER30216.1 - 5.2e-06 26.3 0.1 1.4e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KER30216.1 - 4.1e-05 23.9 2.4 0.0097 16.2 0.5 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER30216.1 - 9.4e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KER30216.1 - 0.0016 19.0 0.1 0.0087 16.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KER30216.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KER30216.1 - 0.0018 17.5 0.0 0.0048 16.1 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KER30216.1 - 0.0022 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KER30216.1 - 0.0071 15.8 0.1 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KER30216.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KER30216.1 - 0.0083 15.5 0.0 0.025 13.9 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.11 KER30216.1 - 0.0096 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KER30216.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KER30216.1 - 0.027 14.2 0.1 0.11 12.1 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 KER30216.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KER30216.1 - 0.033 13.4 0.1 0.092 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KER30216.1 - 0.034 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KER30216.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KER30216.1 - 0.042 13.6 0.5 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain FapA PF03961.13 KER30216.1 - 0.046 12.3 2.0 0.073 11.7 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_14 PF13173.6 KER30216.1 - 0.047 13.7 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KER30216.1 - 0.052 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KER30216.1 - 0.053 13.1 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RILP PF11461.8 KER30216.1 - 0.053 13.7 4.2 0.15 12.3 4.2 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein Parvo_NS1 PF01057.17 KER30216.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 KER30216.1 - 0.094 12.4 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KER30216.1 - 0.1 13.0 0.3 0.64 10.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KER30216.1 - 0.11 12.8 1.4 0.35 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER30216.1 - 0.14 12.6 0.2 1.1 9.8 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Ribonuc_red_lgC PF02867.15 KER30218.1 - 1.5e-170 568.2 0.0 1.7e-166 554.8 0.0 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KER30218.1 - 1.7e-20 72.8 0.0 3.5e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KER30218.1 - 4.7e-09 36.7 0.0 0.0015 19.1 0.0 2.8 2 0 0 2 2 2 2 ATP cone domain Ras PF00071.22 KER30219.1 - 1.6e-53 180.6 0.0 1.9e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER30219.1 - 1.5e-30 105.9 0.0 2e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER30219.1 - 4.5e-17 62.0 0.0 5.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER30219.1 - 1.3e-05 24.9 0.2 9.3e-05 22.0 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER30219.1 - 9.2e-05 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER30219.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KER30219.1 - 0.0045 16.8 0.3 0.36 10.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KER30219.1 - 0.013 15.7 0.1 0.039 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KER30219.1 - 0.021 15.1 0.1 0.053 13.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 KER30219.1 - 0.039 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 KER30219.1 - 0.067 12.8 0.2 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KER30219.1 - 0.085 12.6 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 KER30219.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4207 PF13904.6 KER30220.1 - 2.7 7.6 86.4 0.78 9.4 65.7 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) PH PF00169.29 KER30221.1 - 2e-13 50.7 0.4 4.2e-13 49.7 0.4 1.5 1 0 0 1 1 1 1 PH domain DUF956 PF06115.11 KER30221.1 - 0.1 12.3 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF956) PHD_Oberon PF07227.11 KER30224.1 - 0.039 13.8 3.1 0.04 13.8 2.7 1.3 1 1 0 1 1 1 0 PHD - plant homeodomain finger protein RVT_1 PF00078.27 KER30225.1 - 0.0001 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RUN PF02759.19 KER30226.1 - 4.9e-25 88.0 0.0 1.2e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 RUN domain DNA_pol_A_exoN PF18305.1 KER30226.1 - 0.027 14.7 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Sec2p PF06428.11 KER30226.1 - 0.45 10.5 9.3 6.2 6.9 3.1 3.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p PP2 PF14299.6 KER30229.1 - 0.027 14.5 0.4 0.19 11.8 0.4 2.0 1 1 0 1 1 1 0 Phloem protein 2 Mg_trans_NIPA PF05653.14 KER30230.1 - 2.1e-97 325.8 20.2 2.7e-97 325.5 20.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KER30230.1 - 0.0003 21.0 5.0 0.0003 21.0 5.0 3.5 3 1 1 4 4 4 1 EamA-like transporter family PHO4 PF01384.20 KER30230.1 - 9.1 5.2 12.1 16 4.4 10.9 1.6 1 1 0 1 1 1 0 Phosphate transporter family DUF5427 PF10310.9 KER30231.1 - 0.0078 15.2 0.0 0.0079 15.2 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ig_3 PF13927.6 KER30233.1 - 3.6e-17 62.7 5.3 1.4e-05 25.6 0.2 5.3 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KER30233.1 - 3.8e-12 46.1 0.0 0.0043 17.1 0.0 4.6 4 1 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.17 KER30233.1 - 3.8e-12 46.3 0.4 0.026 14.7 0.0 5.8 6 0 0 6 6 6 4 Immunoglobulin V-set domain ig PF00047.25 KER30233.1 - 8.9e-12 45.0 2.3 0.0022 18.2 0.0 5.3 3 3 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KER30233.1 - 2.2e-09 37.5 0.3 0.00065 20.0 0.0 4.8 5 0 0 5 5 5 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER30233.1 - 0.00072 19.6 0.0 1.4 9.0 0.0 3.8 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 KER30233.1 - 0.00088 18.8 0.0 2.6 7.7 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain DUF4448 PF14610.6 KER30233.1 - 0.0023 17.7 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Ig_5 PF16681.5 KER30233.1 - 0.0047 17.3 0.0 1.4 9.4 0.0 3.7 4 0 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 KER30233.1 - 0.0056 16.9 0.1 0.12 12.6 0.0 3.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain U3_assoc_6 PF08640.11 KER30235.1 - 3.4e-17 62.3 9.1 3.4e-17 62.3 9.1 2.9 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 Uso1_p115_C PF04871.13 KER30235.1 - 0.026 14.9 1.9 0.026 14.9 1.9 3.0 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region IFP_35_N PF07334.13 KER30235.1 - 2.2 8.4 7.9 0.16 12.0 1.8 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Allexi_40kDa PF05549.11 KER30235.1 - 4.5 6.7 9.5 2.2 7.7 2.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein YabA PF06156.13 KER30235.1 - 6.2 7.5 13.3 2.9 8.6 3.0 3.5 3 0 0 3 3 3 0 Initiation control protein YabA Ion_trans_2 PF07885.16 KER30236.1 - 2.2e-35 120.5 15.6 4.4e-18 65.0 4.2 2.5 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 KER30236.1 - 8.7e-05 21.9 5.9 0.034 13.4 0.4 2.4 1 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 KER30236.1 - 2.9 7.7 5.1 1.4 8.8 0.3 2.7 3 0 0 3 3 3 0 Ligand-gated ion channel Pkinase PF00069.25 KER30237.1 - 4.7e-58 196.6 0.0 7.1e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30237.1 - 3.5e-31 108.4 0.0 5.4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_HK97_TLTM PF06120.11 KER30237.1 - 0.043 13.0 4.7 0.027 13.6 2.7 1.6 1 1 0 1 1 1 0 Tail length tape measure protein Med9 PF07544.13 KER30237.1 - 0.28 11.3 2.8 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATP-synt_E PF05680.12 KER30239.1 - 3.9e-15 55.9 0.3 4.9e-15 55.6 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain TnpV PF14198.6 KER30239.1 - 0.036 14.0 0.2 0.047 13.7 0.2 1.1 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Ets PF00178.22 KER30241.1 - 1.2e-31 109.0 2.9 2.6e-31 107.9 2.9 1.6 1 0 0 1 1 1 1 Ets-domain Pyridoxal_deC PF00282.19 KER30243.1 - 3.4e-108 361.7 0.0 8.1e-64 215.7 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 KER30243.1 - 0.15 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Chromosome_seg PF13889.6 KER30244.1 - 4.9e-19 68.2 1.9 1e-18 67.2 1.9 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 KER30244.1 - 7.4e-13 48.9 0.2 6.2e-12 45.9 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) DIRP PF06584.13 KER30245.1 - 3.7e-26 91.4 0.1 1.1e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 DIRP Pro_isomerase PF00160.21 KER30246.1 - 1e-49 168.8 0.0 6.9e-49 166.1 0.0 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C14 PF00656.22 KER30246.1 - 2.8e-07 30.7 0.0 8e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Caspase domain I-set PF07679.16 KER30246.1 - 3.7e-06 26.9 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Rtf2 PF04641.12 KER30246.1 - 2.1e-05 24.1 0.2 0.00011 21.7 0.2 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger Ig_3 PF13927.6 KER30246.1 - 0.00016 22.2 0.1 0.00059 20.4 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain zf-NOSIP PF15906.5 KER30246.1 - 0.0028 17.8 0.1 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein PI3K_P85_iSH2 PF16454.5 KER30249.1 - 4.8e-05 23.0 3.7 6e-05 22.7 3.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Filament PF00038.21 KER30249.1 - 0.00038 20.1 4.8 0.00044 19.9 4.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein APG6_N PF17675.1 KER30249.1 - 0.00079 20.0 6.9 0.00093 19.7 6.9 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Tropomyosin PF00261.20 KER30249.1 - 0.001 18.5 6.3 0.0011 18.3 6.3 1.0 1 0 0 1 1 1 1 Tropomyosin HIP1_clath_bdg PF16515.5 KER30249.1 - 0.0025 18.4 4.6 0.0031 18.1 4.6 1.2 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Cut8 PF08559.10 KER30249.1 - 0.0037 16.9 0.4 0.004 16.8 0.4 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein TPR_MLP1_2 PF07926.12 KER30249.1 - 0.013 15.5 6.2 0.018 15.1 6.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KER30249.1 - 0.018 15.1 7.3 0.02 15.0 7.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PCRF PF03462.18 KER30249.1 - 0.024 14.5 2.2 0.027 14.3 2.2 1.0 1 0 0 1 1 1 0 PCRF domain DUF3287 PF11690.8 KER30249.1 - 0.025 14.3 0.8 0.032 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Spc7 PF08317.11 KER30249.1 - 0.027 13.4 6.0 0.036 12.9 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KER30249.1 - 0.056 12.8 3.1 0.071 12.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KER30249.1 - 0.06 13.2 3.0 0.063 13.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1515 PF07439.11 KER30249.1 - 0.081 13.0 0.7 0.092 12.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Nas2_N PF18265.1 KER30249.1 - 0.094 12.6 2.9 0.58 10.1 0.1 2.2 1 1 1 2 2 2 0 Nas2 N_terminal domain DUF2721 PF11026.8 KER30249.1 - 0.12 12.3 0.7 0.13 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF1664 PF07889.12 KER30249.1 - 0.14 12.2 1.4 0.16 12.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HAUS6_N PF14661.6 KER30249.1 - 0.16 11.5 4.0 0.21 11.1 4.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UPF0449 PF15136.6 KER30249.1 - 0.19 12.2 4.4 0.49 10.9 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4140 PF13600.6 KER30249.1 - 0.28 11.6 3.9 0.21 12.1 2.7 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 KER30249.1 - 0.46 11.1 6.7 0.47 11.1 5.6 1.6 1 1 1 2 2 2 0 SlyX DUF5320 PF17253.2 KER30249.1 - 0.48 11.5 2.1 0.79 10.8 1.4 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ZapB PF06005.12 KER30249.1 - 0.54 10.7 9.6 1.9 9.0 9.5 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 KER30249.1 - 0.63 10.3 5.8 1.3 9.3 5.8 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 KER30249.1 - 0.64 9.2 3.8 0.62 9.3 3.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein Helicase_C PF00271.31 KER30250.1 - 7.2e-11 42.4 0.0 2.3e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Sec63 PF02889.16 KER30250.1 - 2.8e-07 30.0 0.0 4.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KER30250.1 - 2.4e-05 24.2 0.0 7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase PI3_PI4_kinase PF00454.27 KER30252.1 - 1.9e-38 132.7 0.3 1.4e-23 84.0 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KER30252.1 - 3.5e-38 130.9 0.4 1e-37 129.3 0.4 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KER30252.1 - 4.7e-07 29.5 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 KER30252.1 - 2.7e-06 27.3 0.0 6.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 JAB PF01398.21 KER30253.1 - 4.4e-30 104.1 0.0 8.1e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KER30253.1 - 8.6e-14 51.9 0.1 1.7e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KER30253.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain SNF2_N PF00176.23 KER30254.1 - 8.1e-16 57.7 0.0 7.2e-09 34.8 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KER30254.1 - 6.2e-14 52.3 0.0 2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HARP PF07443.13 KER30254.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 HepA-related protein (HARP) Cadherin PF00028.17 KER30255.1 - 3.8e-69 229.2 3.9 1.8e-11 44.3 0.0 10.5 10 2 0 10 10 10 9 Cadherin domain Cadherin_2 PF08266.12 KER30255.1 - 2.1e-18 66.0 0.1 3.3e-11 42.9 0.0 5.7 7 0 0 7 7 7 3 Cadherin-like Cadherin_3 PF16184.5 KER30255.1 - 8.1e-07 29.0 9.0 0.14 12.2 0.1 5.9 5 1 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 KER30255.1 - 0.02 15.2 0.0 15 5.9 0.0 3.7 4 0 0 4 4 4 0 RET Cadherin like domain 1 TLP1_add_C PF18313.1 KER30255.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain FANCI_S4 PF14678.6 KER30256.1 - 5.3e-58 196.1 0.6 5.1e-55 186.3 0.6 2.6 1 1 0 1 1 1 1 FANCI solenoid 4 FANCI_S2 PF14676.6 KER30256.1 - 7e-18 65.5 0.0 2e-17 64.0 0.0 1.9 1 0 0 1 1 1 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 KER30256.1 - 3e-07 30.0 0.6 0.0021 17.4 0.3 3.5 3 2 0 3 3 3 2 FANCI helical domain 2 MDH PF02315.16 KER30259.1 - 0.04 14.0 0.1 0.05 13.7 0.1 1.1 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit S-methyl_trans PF02574.16 KER30261.1 - 2.9e-57 194.5 0.0 3.8e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Smg8_Smg9 PF10220.9 KER30262.1 - 6.9e-108 362.2 0.0 9.5e-70 236.0 0.0 4.0 3 1 0 3 3 3 3 Smg8_Smg9 Cyclin_N PF00134.23 KER30264.1 - 1.1e-24 86.6 0.1 3.1e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER30264.1 - 1.3e-08 34.9 2.8 1.6e-05 25.0 0.1 2.8 3 0 0 3 3 3 2 Cyclin, C-terminal domain HA2 PF04408.23 KER30265.1 - 1.5e-14 54.1 0.5 4.7e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KER30265.1 - 2.7e-08 34.1 0.1 5.3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain NINJA_B PF16136.5 KER30265.1 - 0.018 15.4 3.4 0.018 15.4 3.4 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal Helicase_C PF00271.31 KER30267.1 - 6.8e-08 32.8 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER30267.1 - 5.2e-05 23.1 0.2 0.00028 20.7 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KER30267.1 - 0.0048 17.2 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KER30267.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KER30267.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KER30267.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KER30267.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase LRR_4 PF12799.7 KER30268.1 - 0.032 14.7 19.8 4.2 7.9 0.0 7.0 5 2 2 8 8 8 0 Leucine Rich repeats (2 copies) Ribosomal_L14 PF00238.19 KER30269.1 - 3.7e-14 52.9 0.0 1.7e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e PriA_3primeBD PF17764.1 KER30269.1 - 0.15 11.9 0.1 0.48 10.3 0.1 1.8 1 1 0 1 1 1 0 3′ DNA-binding domain (3′BD) Ribosomal_S10 PF00338.22 KER30270.1 - 0.0079 16.4 0.0 0.02 15.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_S10 PF00338.22 KER30271.1 - 0.0034 17.6 0.0 0.0094 16.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S10p/S20e RVT_1 PF00078.27 KER30273.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) XRCC4 PF06632.12 KER30275.1 - 5.1 5.9 9.0 9.2 5.0 3.8 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cadherin PF00028.17 KER30276.1 - 0.003 18.0 0.0 0.072 13.5 0.0 2.6 2 0 0 2 2 2 1 Cadherin domain CPSase_L_D2 PF02786.17 KER30277.1 - 4.9e-80 268.0 0.0 7.2e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KER30277.1 - 1.2e-43 148.1 0.1 2.3e-43 147.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KER30277.1 - 8.6e-33 112.7 0.0 2.3e-32 111.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KER30277.1 - 4.2e-11 42.5 0.0 1.2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 KER30277.1 - 2.6e-10 40.7 0.2 1.1e-08 35.5 0.2 2.9 2 1 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 KER30277.1 - 1.8e-08 34.2 0.0 3.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KER30277.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KER30277.1 - 2.6e-05 23.9 0.0 0.0001 21.9 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KER30277.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KER30277.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KER30277.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl PF00364.22 KER30278.1 - 8.3e-19 67.2 1.0 1.4e-18 66.5 1.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KER30278.1 - 3.2e-11 42.9 0.6 5e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KER30278.1 - 0.0008 18.7 0.1 1 8.5 0.0 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KER30278.1 - 0.0011 19.7 0.0 1.6 9.5 0.0 2.3 2 0 0 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 KER30278.1 - 0.007 16.3 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 KER30278.1 - 0.0071 16.0 0.6 2.8 7.7 0.1 2.2 1 1 1 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.11 KER30278.1 - 0.013 14.9 0.6 0.033 13.6 0.3 1.8 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 KER30278.1 - 0.15 11.9 0.3 0.21 11.5 0.3 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 KER30278.1 - 0.18 12.1 0.7 2 8.7 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 DUF2118 PF09891.9 KER30278.1 - 0.3 11.0 0.8 1.8 8.5 0.1 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) TFIIA PF03153.13 KER30280.1 - 9.8e-17 62.0 0.3 9.8e-17 62.0 0.3 2.9 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit FMN_red PF03358.15 KER30280.1 - 5.7e-15 55.4 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KER30280.1 - 0.0088 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Spt5_N PF11942.8 KER30280.1 - 1.3 10.0 18.7 5.2 8.1 0.5 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Ribonuclease_T2 PF00445.18 KER30281.1 - 1.3e-21 77.6 0.0 3.5e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 KER30283.1 - 4.2e-43 147.7 0.0 5.1e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family CarbpepA_inh PF02977.15 KER30283.1 - 0.16 11.8 1.2 0.37 10.6 0.3 1.9 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor RVT_1 PF00078.27 KER30285.1 - 6.3e-10 38.9 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tagatose_6_P_K PF08013.11 KER30285.1 - 0.029 13.1 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase PA28_beta PF02252.18 KER30286.1 - 2.1e-57 192.9 0.6 2.7e-57 192.5 0.6 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit NAPRTase_C PF17956.1 KER30287.1 - 4.5e-45 152.6 3.0 5.3e-31 107.3 0.1 2.3 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 KER30287.1 - 1.9e-39 134.9 0.0 4.1e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 KER30287.1 - 6.8e-06 25.9 0.0 0.031 13.9 0.0 2.3 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 KER30287.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Arc_C PF18162.1 KER30287.1 - 0.12 12.3 1.1 0.48 10.3 0.5 2.2 1 1 1 2 2 2 0 Arc C-lobe Sec23_trunk PF04811.15 KER30290.1 - 4.4e-68 229.5 0.0 6.2e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KER30290.1 - 2.6e-27 95.4 0.1 5.3e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KER30290.1 - 3.5e-27 94.2 0.2 7.9e-27 93.1 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KER30290.1 - 3.5e-12 46.2 10.2 7e-12 45.2 10.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KER30290.1 - 1e-08 34.9 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-C3HC4_3 PF13920.6 KER30291.1 - 4.7e-06 26.4 9.5 1.9e-05 24.4 9.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER30291.1 - 0.0013 19.1 12.7 0.0013 19.1 12.7 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KER30291.1 - 0.015 15.1 9.0 0.015 15.1 9.0 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 RMI2 PF16100.5 KER30291.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 zf-RING_5 PF14634.6 KER30291.1 - 0.032 14.2 11.0 0.11 12.5 11.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Trm112p PF03966.16 KER30291.1 - 0.1 13.2 0.4 0.34 11.5 0.4 1.9 1 0 0 1 1 1 0 Trm112p-like protein ATP-grasp_2 PF08442.10 KER30292.1 - 1.1e-61 207.9 0.0 1.6e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KER30292.1 - 9.8e-19 67.7 0.5 1.8e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KER30292.1 - 0.00067 19.2 0.9 0.00093 18.7 0.1 1.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KER30292.1 - 0.0042 16.9 0.1 0.012 15.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KER30292.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Hormone_recep PF00104.30 KER30294.1 - 2.7e-30 105.5 0.0 4.6e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 KER30294.1 - 3.8e-28 97.7 15.7 6.4e-28 97.0 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) TBCC PF07986.12 KER30295.1 - 5.3e-31 106.8 0.0 8.8e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KER30295.1 - 3.8e-30 104.7 7.6 2.3e-16 60.3 0.3 2.2 1 1 1 2 2 2 2 Tubulin-specific chaperone C N-terminal domain CSN8_PSD8_EIF3K PF10075.9 KER30295.1 - 0.023 14.7 0.5 7.2 6.6 0.2 2.4 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family CotJB PF12652.7 KER30295.1 - 0.045 14.0 0.1 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 CotJB protein Serine_rich PF08824.10 KER30295.1 - 0.052 13.5 0.3 5.4 7.0 0.1 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain YfdX PF10938.8 KER30295.1 - 0.064 13.2 0.4 0.15 11.9 0.4 1.6 1 1 0 1 1 1 0 YfdX protein Exonuc_VII_S PF02609.16 KER30295.1 - 0.089 12.9 1.6 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit HSBP1 PF06825.12 KER30295.1 - 1.6 8.7 6.5 11 6.0 0.1 3.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 KER30295.1 - 5.2 7.4 12.4 19 5.6 0.3 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain Pinin_SDK_memA PF04696.13 KER30297.1 - 2.6e-28 98.7 13.8 2.6e-28 98.7 13.8 1.9 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 KER30297.1 - 2.2e-08 34.8 4.8 2.2e-08 34.8 4.8 4.2 2 2 1 4 4 4 1 pinin/SDK conserved region Prefoldin PF02996.17 KER30297.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit CaKB PF03185.15 KER30299.1 - 7.2e-20 71.5 6.2 1e-19 71.0 6.2 1.2 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit MDMPI_C PF07398.11 KER30301.1 - 0.092 13.6 0.0 0.15 13.0 0.0 1.4 1 0 0 1 1 1 0 MDMPI C-terminal domain CD34_antigen PF06365.12 KER30302.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 KER30302.1 - 0.0033 17.3 7.3 0.064 13.2 7.3 2.4 1 1 0 1 1 1 1 TMEM154 protein family Mucin PF01456.17 KER30302.1 - 0.0051 16.8 1.8 0.0051 16.8 1.8 2.2 2 0 0 2 2 2 1 Mucin-like glycoprotein DAG1 PF05454.11 KER30302.1 - 0.014 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 KER30302.1 - 0.023 15.5 0.0 0.16 12.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 KER30302.1 - 0.029 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cadherin_C_2 PF16492.5 KER30302.1 - 0.045 14.5 0.0 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4448 PF14610.6 KER30302.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pkinase PF00069.25 KER30307.1 - 3.7e-26 92.1 0.0 6.1e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER30307.1 - 3.5e-13 49.5 0.0 3.9e-10 39.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase DUF4817 PF16087.5 KER30310.1 - 7.9e-12 44.8 0.4 3.4e-11 42.8 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain (DUF4817) DDE_Tnp_IS1595 PF12762.7 KER30310.1 - 0.014 15.4 0.4 0.041 13.9 0.1 1.8 2 0 0 2 2 2 0 ISXO2-like transposase domain TED_complement PF07678.14 KER30311.1 - 1.7e-71 240.8 0.0 2.6e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 KER30311.1 - 8.1e-23 81.0 0.0 3e-22 79.1 0.0 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain MG3 PF17791.1 KER30311.1 - 4.2e-20 71.8 0.0 1.6e-19 70.0 0.0 2.1 1 0 0 1 1 1 1 Macroglobulin domain MG3 A2M PF00207.22 KER30311.1 - 7.3e-16 57.8 0.1 3.1e-15 55.8 0.1 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 KER30311.1 - 1e-08 35.5 0.1 6.4e-06 26.5 0.1 3.4 2 1 0 2 2 2 1 MG2 domain DSL PF01414.19 KER30311.1 - 1.9e-05 24.9 4.7 1.9e-05 24.9 4.7 3.6 2 1 1 3 3 3 1 Delta serrate ligand A2M_BRD PF07703.14 KER30311.1 - 0.00023 21.5 0.1 0.02 15.2 0.0 3.3 4 0 0 4 4 4 1 Alpha-2-macroglobulin bait region domain EGF_2 PF07974.13 KER30311.1 - 0.0035 17.7 41.3 0.19 12.1 12.1 4.2 3 0 0 3 3 3 2 EGF-like domain Prenyltrans PF00432.21 KER30311.1 - 0.03 14.1 0.8 44 3.9 0.0 3.8 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat HRXXH PF13933.6 KER30311.1 - 0.045 13.3 0.3 0.098 12.2 0.3 1.5 1 0 0 1 1 1 0 Putative peptidase family RNA_pol_inhib PF16857.5 KER30311.1 - 0.17 11.7 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase inhibitor DUF3421 PF11901.8 KER30312.1 - 1.2e-32 112.3 1.4 8.7e-28 96.6 0.2 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3421) CAP PF00188.26 KER30312.1 - 1.1e-11 45.6 0.0 8.4e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3421 PF11901.8 KER30314.1 - 9.3e-34 115.9 1.5 1.3e-31 108.9 0.4 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 KER30315.1 - 6.7e-42 142.1 8.0 1.4e-38 131.4 1.8 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) Enolase_C PF00113.22 KER30317.1 - 5.3e-143 475.6 0.0 7.8e-143 475.1 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KER30317.1 - 1.4e-51 174.1 0.0 2.1e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KER30317.1 - 9.3e-11 41.7 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KER30317.1 - 0.00012 21.3 0.8 0.0014 17.8 0.1 2.1 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus EMP70 PF02990.16 KER30319.1 - 4.7e-179 596.4 15.9 4.7e-179 596.4 15.9 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 RT_RNaseH PF17917.1 KER30320.1 - 0.015 15.5 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Stevor PF17410.2 KER30321.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RFX_DNA_binding PF02257.15 KER30322.1 - 2.1e-31 108.4 0.0 5.2e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Pkinase PF00069.25 KER30323.1 - 3.9e-61 206.7 0.0 5.3e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 KER30323.1 - 2.9e-49 168.1 0.0 4.1e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 KER30323.1 - 4.3e-46 157.3 0.0 6.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER30323.1 - 8.7e-05 21.5 0.0 8.7e-05 21.5 0.0 3.0 4 0 0 4 4 4 1 Fungal protein kinase Kinase-like PF14531.6 KER30323.1 - 0.0008 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER30323.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KER30323.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KER30323.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DNA_pol_D_N PF18018.1 KER30324.1 - 2.1e-32 112.0 0.0 3.1e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KER30324.1 - 4.1e-19 68.8 0.0 6.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Innexin PF00876.18 KER30325.1 - 3.4e-172 572.5 12.1 2.7e-57 194.7 0.1 6.0 5 1 1 6 6 6 6 Innexin Casc1 PF12366.8 KER30325.1 - 0.055 13.0 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 YfzA PF14118.6 KER30325.1 - 1.3 9.5 7.5 6.1 7.3 0.0 4.7 5 0 0 5 5 5 0 YfzA-like protein eIF-3c_N PF05470.12 KER30326.1 - 2.9 6.1 6.5 3.7 5.7 6.5 1.2 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.13 KER30326.1 - 6.1 6.7 22.6 20 5.0 17.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Bax1-I PF01027.20 KER30328.1 - 1.1e-49 169.1 23.3 1.2e-49 168.9 23.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2157 PF09925.9 KER30328.1 - 0.046 13.5 11.7 0.094 12.5 11.7 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF5326 PF17260.2 KER30328.1 - 0.21 11.8 0.3 0.21 11.8 0.3 3.3 3 2 1 4 4 4 0 Family of unknown function (DUF5326) PYC_OADA PF02436.18 KER30329.1 - 1.6e-70 236.9 0.1 2.4e-70 236.4 0.1 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 KER30329.1 - 1.3e-25 90.5 0.1 2.1e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KER30329.1 - 5.5e-15 55.0 4.7 7.9e-15 54.4 2.9 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KER30329.1 - 3.6e-09 36.3 1.9 4.6e-06 26.4 0.1 3.2 3 1 1 4 4 4 2 Biotin-lipoyl like RnfC_N PF13375.6 KER30329.1 - 5.5e-05 23.1 0.4 0.00012 21.9 0.4 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 KER30329.1 - 0.0014 19.3 0.5 0.011 16.5 0.4 2.5 2 1 0 2 2 1 1 HlyD family secretion protein HlyD_D23 PF16576.5 KER30329.1 - 0.0015 17.8 0.5 0.039 13.2 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 KER30329.1 - 0.0021 17.6 0.5 0.0042 16.6 0.5 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 KER30329.1 - 0.012 15.5 1.4 0.019 14.9 0.2 1.9 2 0 0 2 2 2 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 KER30329.1 - 0.045 13.5 0.6 0.27 11.0 0.1 2.5 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Carb_kinase PF01256.17 KER30329.1 - 1 8.8 5.7 0.49 9.8 0.4 2.1 2 0 0 2 2 2 0 Carbohydrate kinase CPSase_L_D2 PF02786.17 KER30330.1 - 4.7e-78 261.5 0.1 7.4e-78 260.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KER30330.1 - 7.2e-36 123.1 0.0 1.6e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KER30330.1 - 2.2e-33 114.6 0.0 5.2e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KER30330.1 - 7.3e-08 32.2 0.0 2.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KER30330.1 - 1.7e-06 27.7 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KER30330.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Baculo_PEP_C PF04513.12 KER30332.1 - 0.00042 20.4 4.3 0.045 13.8 1.1 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 KER30332.1 - 0.0039 17.1 3.5 0.035 14.0 2.8 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1451 PF07295.11 KER30332.1 - 0.0043 17.1 0.7 0.0082 16.2 0.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain Prefoldin_2 PF01920.20 KER30332.1 - 0.018 15.0 4.0 0.018 15.0 4.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit HP1451_C PF18472.1 KER30332.1 - 0.11 12.5 0.6 16 5.6 0.0 3.1 1 1 2 3 3 3 0 HP1451 C-terminal domain YojJ PF10372.9 KER30332.1 - 0.12 12.5 5.3 2.6 8.2 0.2 3.5 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus DUF883 PF05957.13 KER30332.1 - 0.12 12.9 0.5 0.38 11.4 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DHC_N1 PF08385.12 KER30334.1 - 0.0018 17.0 0.0 0.0031 16.2 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 BPL_LplA_LipB PF03099.19 KER30335.1 - 2e-06 27.7 0.0 1.1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KER30335.1 - 7.9e-05 22.5 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF4071 PF13281.6 KER30336.1 - 3.7e-94 315.8 0.0 5.6e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 KER30336.1 - 1.7e-65 221.0 0.0 2.7e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30336.1 - 2.1e-43 148.5 0.0 3.6e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER30336.1 - 0.0006 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER30336.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KER30336.1 - 0.041 13.8 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KER30336.1 - 0.13 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 RIO1 family DUF3301 PF11743.8 KER30340.1 - 0.017 14.8 0.3 0.029 14.0 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) IPK PF03770.16 KER30342.1 - 1.6e-22 80.4 0.0 2.5e-22 79.7 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase WD40 PF00400.32 KER30344.1 - 0.00086 20.1 2.9 3.9 8.5 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Lge1 PF11488.8 KER30344.1 - 0.13 12.4 2.1 0.29 11.3 1.5 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Atg14 PF10186.9 KER30344.1 - 3.8 6.5 6.2 6.3 5.8 6.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C3HC4_3 PF13920.6 KER30345.1 - 4.7e-12 45.6 11.7 1.6e-11 43.9 11.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.10 KER30345.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 FERM C-terminal PH-like domain zf-RING_5 PF14634.6 KER30345.1 - 4.2 7.4 16.8 0.35 10.9 11.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KER30345.1 - 7.2 6.6 22.0 0.3 11.0 15.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Laminin_G_2 PF02210.24 KER30347.1 - 5.2e-09 36.7 0.0 4.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KER30347.1 - 4.5e-08 33.2 62.3 5.4e-05 23.4 5.6 6.7 6 0 0 6 6 6 4 EGF-like domain Laminin_G_1 PF00054.23 KER30347.1 - 0.013 15.8 0.0 0.94 9.7 0.0 2.6 2 1 0 2 2 2 0 Laminin G domain EGF PF00008.27 KER30348.1 - 1.4e-05 25.3 5.6 1.4e-05 25.3 5.6 1.9 2 0 0 2 2 1 1 EGF-like domain TMEM154 PF15102.6 KER30348.1 - 9.5e-05 22.3 0.1 0.00018 21.5 0.0 1.5 2 0 0 2 2 1 1 TMEM154 protein family Shisa PF13908.6 KER30348.1 - 0.0013 19.0 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KER30348.1 - 0.0024 18.7 0.0 0.0042 17.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 KER30348.1 - 0.0037 17.1 8.1 0.0064 16.3 8.1 1.3 1 0 0 1 1 1 1 TMIE protein Stevor PF17410.2 KER30348.1 - 0.0081 15.7 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame TMEM52 PF14979.6 KER30348.1 - 0.0087 16.0 1.9 0.0094 15.9 1.0 1.5 2 0 0 2 2 1 1 Transmembrane 52 SCIMP PF15050.6 KER30348.1 - 0.0095 16.4 2.4 0.021 15.3 2.4 1.5 1 0 0 1 1 1 1 SCIMP protein DUF4834 PF16118.5 KER30348.1 - 0.023 15.6 0.1 0.08 13.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Orthoreo_P10 PF07204.11 KER30348.1 - 0.024 14.6 2.4 0.038 14.0 2.4 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Hanta_G2 PF01561.16 KER30348.1 - 0.024 13.3 1.2 0.033 12.8 1.2 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 Herpes_gE PF02480.16 KER30348.1 - 0.032 13.0 0.1 0.063 12.0 0.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.9 KER30348.1 - 0.032 13.0 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rhabdo_glycop PF00974.18 KER30348.1 - 0.032 12.7 1.4 0.043 12.3 1.4 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF3844 PF12955.7 KER30348.1 - 0.036 14.2 3.9 0.063 13.4 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Hum_adeno_E3A PF05393.11 KER30348.1 - 0.054 13.5 2.9 0.088 12.8 2.9 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF4726 PF15855.5 KER30348.1 - 0.059 13.6 0.3 6.8 7.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) DAG1 PF05454.11 KER30348.1 - 0.06 12.7 0.7 0.11 11.8 0.7 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4381 PF14316.6 KER30348.1 - 0.075 13.3 1.5 0.12 12.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Innexin PF00876.18 KER30348.1 - 0.081 12.2 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Innexin DUF5385 PF17359.2 KER30348.1 - 0.099 12.2 0.2 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) FAO_M PF16350.5 KER30348.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain MLANA PF14991.6 KER30348.1 - 0.2 12.0 0.1 0.34 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A SIT PF15330.6 KER30348.1 - 0.34 11.4 1.1 0.36 11.3 0.1 1.5 2 0 0 2 2 1 0 SHP2-interacting transmembrane adaptor protein, SIT Baculo_F PF12259.8 KER30348.1 - 0.36 9.3 1.1 0.46 9.0 1.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein WBP-1 PF11669.8 KER30348.1 - 0.37 11.4 5.5 0.98 10.1 5.4 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 TMEM156 PF15106.6 KER30348.1 - 0.46 9.9 2.1 0.88 9.0 2.1 1.3 1 0 0 1 1 1 0 TMEM156 protein family Pox_EPC_I2-L1 PF12575.8 KER30348.1 - 1.1 9.5 3.2 2 8.7 3.2 1.3 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Prominin PF05478.11 KER30348.1 - 1.4 6.8 4.0 1.9 6.4 4.0 1.0 1 0 0 1 1 1 0 Prominin DUF3827 PF12877.7 KER30348.1 - 3.9 5.7 5.0 5.3 5.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF_2 PF07974.13 KER30348.1 - 6.8 7.2 16.3 0.16 12.4 8.7 2.3 2 1 0 2 2 1 0 EGF-like domain ACT_3 PF10000.9 KER30349.1 - 0.068 13.1 0.1 0.072 13.0 0.1 1.1 1 0 0 1 1 1 0 ACT domain SRP68 PF16969.5 KER30351.1 - 4.3e-150 501.4 2.0 5.4e-150 501.1 2.0 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 KER30351.1 - 0.033 13.0 2.1 0.53 9.0 0.0 3.0 3 1 0 3 3 3 0 BRO1-like domain AHH PF14412.6 KER30351.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH ARID PF01388.21 KER30352.1 - 5.9e-08 33.3 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 KER30352.1 - 2.5e-06 28.0 0.1 5.4e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain zf-C2H2_aberr PF17017.5 KER30352.1 - 0.079 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KER30352.1 - 0.12 12.3 0.1 0.46 10.4 0.1 2.0 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 KER30352.1 - 0.13 12.9 3.0 3.4 8.4 0.2 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain PLAC8 PF04749.17 KER30353.1 - 7.8e-08 33.2 18.1 1.7e-07 32.2 18.1 1.6 1 1 0 1 1 1 1 PLAC8 family DBP PF12361.8 KER30356.1 - 0.035 14.0 0.2 0.044 13.6 0.2 1.0 1 0 0 1 1 1 0 Duffy-antigen binding protein CAP PF00188.26 KER30357.1 - 2e-05 25.5 0.1 2.3e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KER30358.1 - 5e-06 27.4 0.3 5e-06 27.4 0.3 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family HTH_48 PF17906.1 KER30358.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 HTH domain in Mos1 transposase PLAC8 PF04749.17 KER30360.1 - 2e-11 44.8 11.7 3.6e-11 43.9 11.7 1.4 1 1 0 1 1 1 1 PLAC8 family NopRA1 PF16201.5 KER30361.1 - 2.3e-44 151.4 0.5 8e-44 149.6 0.5 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 KER30361.1 - 1.1e-33 117.0 2.1 7.3e-33 114.3 0.6 2.9 2 1 0 2 2 2 1 Ribosome 60S biogenesis N-terminal C2 PF00168.30 KER30362.1 - 9.7e-13 48.3 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KER30362.1 - 0.019 15.1 0.6 0.18 12.0 0.6 2.3 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KER30363.1 - 3.1e-08 33.8 0.0 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 2 C2 domain DAGK_cat PF00781.24 KER30364.1 - 5.2e-20 71.3 0.0 9e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CENP-O PF09496.10 KER30364.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component SMN PF06003.12 KER30366.1 - 2.8e-05 23.5 0.4 4.7e-05 22.8 0.4 1.3 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) Tudor_2 PF18104.1 KER30366.1 - 0.00079 19.1 0.5 0.0069 16.0 0.1 2.2 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 KER30366.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) TUDOR PF00567.24 KER30366.1 - 0.028 14.5 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Tudor domain DUF5128 PF17170.4 KER30366.1 - 0.074 12.2 1.2 0.38 9.9 0.2 2.0 1 1 0 2 2 2 0 6-bladed beta-propeller Tudor_3 PF18115.1 KER30366.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain FAM184 PF15665.5 KER30367.1 - 0.0014 18.5 30.9 0.0014 18.5 30.9 5.5 1 1 4 5 5 5 2 Family with sequence similarity 184, A and B DUF382 PF04037.13 KER30367.1 - 0.0019 18.4 1.8 0.0019 18.4 1.8 4.2 4 2 2 6 6 6 1 Domain of unknown function (DUF382) CopC PF04234.12 KER30367.1 - 4.3 8.4 5.3 4.4 8.4 0.0 3.7 3 1 1 4 4 4 0 CopC domain RVT_1 PF00078.27 KER30368.1 - 3.6e-07 29.9 0.0 8.5e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alba PF01918.21 KER30368.1 - 2.8e-05 23.8 0.3 7.6e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Alba TPR_1 PF00515.28 KER30369.1 - 1.7e-46 154.2 25.1 4.6e-09 35.7 1.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KER30369.1 - 1.1e-34 115.7 16.9 2.2e-07 30.5 0.6 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KER30369.1 - 3.6e-27 92.3 17.8 1.1e-05 25.3 1.9 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 KER30369.1 - 5.2e-25 86.8 9.9 4.9e-09 35.7 0.4 4.5 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 KER30369.1 - 2.9e-22 78.8 11.0 1.2e-08 35.1 0.2 5.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KER30369.1 - 3.5e-18 64.7 0.5 0.0075 17.0 0.1 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KER30369.1 - 1.6e-16 60.6 6.4 6.3e-05 23.4 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat STI1 PF17830.1 KER30369.1 - 5e-13 48.8 1.1 1.6e-12 47.2 1.1 1.9 1 0 0 1 1 1 1 STI1 domain TPR_16 PF13432.6 KER30369.1 - 8.2e-13 48.8 2.1 0.0016 19.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KER30369.1 - 1.3e-10 40.5 7.5 0.015 15.3 0.2 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KER30369.1 - 9.4e-10 38.5 8.9 0.16 12.7 0.2 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KER30369.1 - 1.2e-09 38.2 0.4 0.0019 18.3 0.0 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER30369.1 - 1.5e-08 34.4 17.6 0.0013 18.9 0.5 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.8 KER30369.1 - 8.4e-08 31.6 9.5 0.00012 21.2 0.0 3.8 1 1 3 4 4 4 2 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 KER30369.1 - 5.2e-06 26.4 12.3 0.67 10.1 0.0 5.6 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KER30369.1 - 3.7e-05 23.4 10.3 0.87 9.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KER30369.1 - 6.2e-05 22.5 1.4 0.00014 21.3 0.2 2.1 3 1 0 3 3 3 1 MalT-like TPR region ANAPC3 PF12895.7 KER30369.1 - 8.1e-05 22.8 16.5 0.0014 18.8 2.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KER30369.1 - 0.00073 19.5 7.6 1.9 8.5 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF627 PF04781.12 KER30369.1 - 0.0022 18.0 6.2 0.39 10.7 0.0 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF627) TPR_21 PF09976.9 KER30369.1 - 0.007 16.1 10.6 0.72 9.5 0.2 4.0 2 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KER30369.1 - 0.018 14.2 2.8 0.84 8.8 0.1 3.3 2 2 0 3 3 3 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 KER30369.1 - 0.032 14.1 2.0 0.15 11.8 1.2 2.2 2 1 0 2 2 2 0 ATP synthase subunit D MIT PF04212.18 KER30369.1 - 0.043 13.9 13.9 0.39 10.8 0.1 4.8 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 KER30369.1 - 0.066 12.2 0.2 0.21 10.6 0.1 1.8 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Peptidase_C2 PF00648.21 KER30369.1 - 0.081 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease YfiO PF13525.6 KER30369.1 - 0.15 11.8 4.8 0.45 10.2 0.2 2.6 1 1 0 2 2 2 0 Outer membrane lipoprotein CCDC-167 PF15188.6 KER30369.1 - 0.21 11.9 1.8 0.57 10.6 0.6 2.4 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 SHNi-TPR PF10516.9 KER30369.1 - 0.22 11.0 3.3 25 4.4 0.0 4.3 4 0 0 4 4 4 0 SHNi-TPR RPN7 PF10602.9 KER30369.1 - 0.35 10.5 13.9 1.4 8.6 0.2 4.3 2 1 3 5 5 5 0 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.6 KER30369.1 - 0.64 10.5 7.3 4.5 7.7 0.3 3.7 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation TssO PF17561.2 KER30369.1 - 0.66 10.1 6.1 6.5 6.9 0.1 2.7 1 1 1 2 2 2 0 Type VI secretion system, TssO Dynein_IC2 PF11540.8 KER30370.1 - 5.4e-12 45.5 0.7 1.1e-11 44.5 0.7 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 KER30370.1 - 1.2e-09 38.7 11.5 0.029 15.2 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 KER30370.1 - 0.15 11.3 0.0 3.8 6.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain Peptidase_C1 PF00112.23 KER30373.1 - 1e-47 163.1 0.1 1.7e-47 162.3 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease MULE PF10551.9 KER30373.1 - 5e-20 71.7 0.1 1.1e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Inhibitor_I29 PF08246.12 KER30373.1 - 8.1e-15 55.0 1.0 2.4e-14 53.5 1.0 1.9 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Claudin_3 PF06653.11 KER30373.1 - 0.13 12.2 0.1 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Peptidase_C1 PF00112.23 KER30374.1 - 2.4e-83 279.5 0.3 3e-83 279.2 0.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER30374.1 - 1.4e-13 51.0 1.6 2.7e-13 50.1 1.6 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER30374.1 - 6.7e-05 21.8 0.5 0.038 12.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KER30375.1 - 1.6e-129 430.5 0.0 4.6e-65 219.8 0.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER30375.1 - 3.7e-12 45.8 5.1 0.0001 21.2 0.0 3.7 4 0 0 4 4 4 3 Peptidase C1-like family Inhibitor_I29 PF08246.12 KER30375.1 - 1.7e-11 44.4 1.0 4e-11 43.2 1.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 KER30376.1 - 0.0013 18.9 0.0 0.0013 18.8 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 KER30377.1 - 3.8e-134 445.6 0.0 8.8e-69 231.9 0.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER30377.1 - 1.5e-17 63.8 11.8 1.4e-09 38.2 0.8 2.4 2 0 0 2 2 2 2 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER30377.1 - 3.1e-09 36.1 12.0 0.00043 19.2 0.2 4.1 4 0 0 4 4 4 2 Peptidase C1-like family RNase_E_G PF10150.9 KER30377.1 - 0.0044 16.5 0.3 0.36 10.2 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease E/G family Peptidase_C2 PF00648.21 KER30377.1 - 0.0065 15.5 0.1 0.47 9.4 0.0 2.5 2 0 0 2 2 2 1 Calpain family cysteine protease Retrotrans_gag PF03732.17 KER30377.1 - 0.22 11.8 1.6 8.4 6.7 0.4 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein NifU PF01106.17 KER30377.1 - 0.24 11.6 0.6 17 5.7 0.0 2.8 3 0 0 3 3 3 0 NifU-like domain Peptidase_C1 PF00112.23 KER30378.1 - 1.9e-69 234.1 0.3 2.6e-69 233.6 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER30378.1 - 7.1e-11 42.4 3.7 1.2e-10 41.6 3.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) RNase_E_G PF10150.9 KER30378.1 - 0.06 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family Retrotrans_gag PF03732.17 KER30378.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Peptidase_C1 PF00112.23 KER30379.1 - 1.3e-73 247.7 2.6 1.8e-73 247.3 2.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER30379.1 - 6.5e-10 39.3 4.3 1.2e-09 38.5 4.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER30379.1 - 4.9e-05 22.3 1.9 0.0014 17.5 0.2 2.7 3 0 0 3 3 3 2 Peptidase C1-like family Neur_chan_memb PF02932.16 KER30380.1 - 2.1e-09 37.8 4.5 1.2e-05 25.5 4.5 2.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 KER30381.1 - 3e-47 160.9 1.3 3.5e-47 160.6 1.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER30381.1 - 2.7e-11 44.0 12.1 3.7e-11 43.5 12.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2070 PF09843.9 KER30381.1 - 7.3 4.8 9.5 9.6 4.4 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DEAD PF00270.29 KER30383.1 - 1.3e-45 155.3 0.0 2.2e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER30383.1 - 8.4e-29 100.1 0.0 6.3e-28 97.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 KER30383.1 - 5.8e-24 84.2 0.1 2.7e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 KER30383.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KER30383.1 - 5.8e-05 22.4 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KER30383.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fumble PF03630.14 KER30384.1 - 4.1e-119 397.6 0.0 5.3e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 KER30384.1 - 2.7e-39 135.1 0.0 4.3e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Voltage_CLC PF00654.20 KER30386.1 - 4.2e-87 292.7 31.6 5.3e-87 292.3 31.6 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KER30386.1 - 7.5e-14 51.9 0.1 1.4e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF3382 PF11862.8 KER30386.1 - 1.9 8.8 8.6 0.13 12.5 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Hormone_3 PF00159.18 KER30389.1 - 0.058 13.5 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Pancreatic hormone peptide dsDNA_bind PF01984.20 KER30390.1 - 1.1e-26 93.3 7.0 1.3e-26 93.0 7.0 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain FeoC PF09012.10 KER30390.1 - 0.013 15.6 0.1 0.035 14.2 0.1 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator UPF0154 PF03672.13 KER30390.1 - 0.022 14.8 2.7 0.052 13.6 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) ArgJ PF01960.18 KER30390.1 - 0.025 13.3 0.2 0.03 13.1 0.2 1.1 1 0 0 1 1 1 0 ArgJ family AMP-binding PF00501.28 KER30391.1 - 7e-35 120.4 0.1 1.7e-32 112.6 0.1 2.9 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KER30391.1 - 0.053 14.5 0.0 0.15 13.1 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Maf1 PF09174.10 KER30393.1 - 7.3e-51 172.8 4.6 2.2e-50 171.2 4.6 1.7 1 1 0 1 1 1 1 Maf1 regulator BCDHK_Adom3 PF10436.9 KER30394.1 - 1.1e-22 80.6 0.4 5.3e-22 78.4 0.4 2.0 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KER30394.1 - 4.4e-08 33.6 0.0 0.0051 17.3 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRM PF02005.16 KER30395.1 - 1.6e-109 366.6 0.0 5.3e-93 312.2 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KER30395.1 - 4.9e-08 33.0 0.0 8.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KER30395.1 - 0.00048 19.8 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KER30395.1 - 0.001 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 KER30395.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Spermine_synth PF01564.17 KER30395.1 - 0.0078 15.6 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain PrmA PF06325.13 KER30395.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KER30395.1 - 0.017 15.8 0.1 0.046 14.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KER30395.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 KER30395.1 - 0.088 12.4 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Tubulin PF00091.25 KER30396.1 - 4.2e-67 226.2 0.0 5.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER30396.1 - 3.5e-50 169.4 0.0 5.8e-50 168.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER30396.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Myosin_tail_1 PF01576.19 KER30397.1 - 0.00014 19.8 26.7 0.00014 19.8 26.7 2.8 2 1 0 2 2 2 1 Myosin tail HIP1_clath_bdg PF16515.5 KER30397.1 - 0.0039 17.8 7.3 0.0039 17.8 7.3 6.1 2 1 4 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 YbaB_DNA_bd PF02575.16 KER30397.1 - 0.01 16.1 0.0 0.01 16.1 0.0 4.7 5 1 1 6 6 5 0 YbaB/EbfC DNA-binding family Fib_alpha PF08702.10 KER30397.1 - 0.01 16.0 41.0 0.091 12.9 9.8 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.6 KER30397.1 - 0.02 15.0 7.4 0.02 15.0 7.4 6.5 3 2 2 6 6 6 0 Centrosome localisation domain of PPC89 FemAB PF02388.16 KER30397.1 - 0.045 12.6 0.3 0.045 12.6 0.3 3.9 2 2 2 4 4 4 0 FemAB family V_ATPase_I PF01496.19 KER30397.1 - 0.053 11.5 25.7 0.11 10.3 3.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 KER30397.1 - 0.057 13.9 18.1 2.9 8.4 3.0 4.7 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KER30397.1 - 0.12 11.7 57.0 0.45 9.8 14.0 3.5 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KER30397.1 - 0.29 10.5 45.7 0.15 11.5 27.0 2.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 KER30397.1 - 0.58 7.6 47.6 0.033 11.7 23.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KER30397.1 - 0.73 8.7 56.3 0.23 10.3 13.5 3.7 2 1 3 5 5 5 0 Spc7 kinetochore protein IFT57 PF10498.9 KER30397.1 - 0.74 8.7 40.0 5.3 5.9 10.5 3.3 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KER30397.1 - 1.3 9.1 28.2 0.1 12.7 4.6 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KER30397.1 - 1.6 8.8 54.9 1.5 8.8 4.9 4.8 2 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 KER30397.1 - 1.6 8.7 25.5 0.21 11.6 1.9 4.1 2 1 1 3 3 3 0 Laminin Domain II FlaC_arch PF05377.11 KER30397.1 - 2.2 8.8 27.6 2.4 8.6 2.3 6.6 4 3 1 6 6 6 0 Flagella accessory protein C (FlaC) FPP PF05911.11 KER30397.1 - 4.7 5.3 36.2 0.047 11.9 23.9 2.4 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 KER30397.1 - 5 6.4 40.8 52 3.1 13.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HOOK PF05622.12 KER30397.1 - 9.2 4.3 45.3 0.42 8.7 39.1 1.9 2 1 0 2 2 2 0 HOOK protein ATG16 PF08614.11 KER30397.1 - 9.3 6.4 64.3 1.2 9.3 19.8 4.8 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Cast PF10174.9 KER30398.1 - 5.1e-65 220.1 122.3 1.5e-41 142.5 54.9 10.6 5 5 3 8 8 8 4 RIM-binding protein of the cytomatrix active zone Seryl_tRNA_N PF02403.22 KER30398.1 - 0.0036 17.5 1.7 0.0036 17.5 1.7 19.8 11 7 10 21 21 21 4 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 KER30398.1 - 0.0036 17.4 2.1 0.0036 17.4 2.1 17.9 7 6 9 17 17 17 3 Tropomyosin like Ufm1 PF03671.14 KER30400.1 - 6.8e-29 99.8 0.0 9.7e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Phage_r1t_holin PF16945.5 KER30401.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Peptidase_S24 PF00717.23 KER30404.1 - 1.3e-10 41.1 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KER30404.1 - 3e-05 23.8 0.0 0.00073 19.3 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Porin_3 PF01459.22 KER30406.1 - 3.1e-35 121.9 2.1 6.8e-34 117.5 1.1 2.1 2 0 0 2 2 2 2 Eukaryotic porin WHAMM-JMY_N PF15920.5 KER30406.1 - 0.15 12.0 0.2 3 7.8 0.0 2.9 3 0 0 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated DUF4620 PF15399.6 KER30407.1 - 0.067 13.5 0.1 0.097 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) GPS PF01825.21 KER30411.1 - 0.0069 16.9 1.2 0.0074 16.8 0.0 1.7 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif C2 PF00168.30 KER30413.1 - 2.5e-21 75.9 0.1 5.7e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KER30413.1 - 0.00022 21.2 0.0 0.021 14.7 0.0 2.5 2 1 0 2 2 2 1 Phosphoinositide 3-kinase C2 Baculo_11_kDa PF06143.11 KER30413.1 - 0.077 12.6 2.3 0.21 11.2 2.3 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family TRP PF06011.12 KER30413.1 - 0.22 10.2 1.9 0.32 9.7 1.9 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PRIMA1 PF16101.5 KER30413.1 - 0.67 10.0 2.7 0.42 10.6 0.9 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 C2 PF00168.30 KER30414.1 - 3e-24 85.3 0.0 1.9e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KER30414.1 - 0.00015 21.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 Ribosomal_L6 PF00347.23 KER30414.1 - 0.099 13.3 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L6 C2 PF00168.30 KER30415.1 - 5.7e-27 94.0 0.2 2.3e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 C2 domain LapA_dom PF06305.11 KER30415.1 - 0.077 12.8 1.1 0.13 12.1 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 KER30415.1 - 0.2 10.3 0.3 0.31 9.8 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 KER30415.1 - 2.9 8.0 5.7 6.1 6.9 5.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RhoGAP PF00620.27 KER30416.1 - 2.8e-07 30.5 0.0 0.00038 20.3 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain DUF3318 PF11780.8 KER30416.1 - 0.044 13.7 0.2 0.47 10.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3318) ESSS PF10183.9 KER30419.1 - 4e-10 39.8 0.0 4.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA PF00004.29 KER30420.1 - 4.5e-12 46.5 0.0 1.3e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 KER30420.1 - 0.00068 19.2 0.4 0.00068 19.2 0.4 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_16 PF13191.6 KER30420.1 - 0.33 11.3 3.0 0.34 11.3 0.0 2.7 3 2 0 3 3 3 0 AAA ATPase domain AAA_6 PF12774.7 KER30421.1 - 8.5e-126 419.3 0.0 1.4e-103 346.3 0.0 2.6 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER30421.1 - 2.3e-90 303.6 5.2 2.3e-51 175.2 0.2 3.2 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KER30421.1 - 9.7e-70 234.1 0.1 4.4e-68 228.7 0.3 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KER30421.1 - 3.6e-42 144.5 0.0 9.6e-41 139.8 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KER30421.1 - 8.9e-35 120.4 2.2 1.4e-34 119.7 0.1 2.5 3 0 0 3 3 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 KER30421.1 - 1.1e-33 116.1 0.0 1.4e-19 70.5 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KER30421.1 - 1.2e-31 109.2 0.0 2.8e-29 101.6 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KER30421.1 - 4.3e-30 104.9 5.1 9.2e-30 103.8 5.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KER30421.1 - 1.9e-29 102.6 0.0 3.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DHC_N1 PF08385.12 KER30421.1 - 2.6e-22 79.2 3.9 1.3e-17 63.7 0.0 4.7 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 KER30421.1 - 6.3e-22 78.0 0.0 3.9e-18 65.6 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 KER30421.1 - 7.1e-11 42.5 1.5 0.0034 17.6 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KER30421.1 - 4.7e-07 30.3 24.5 0.0025 18.2 0.0 7.3 7 1 0 7 7 4 2 AAA ATPase domain ABC_tran PF00005.27 KER30421.1 - 5.6e-06 26.9 1.2 0.012 16.1 0.0 4.0 4 0 0 4 4 2 1 ABC transporter RsgA_GTPase PF03193.16 KER30421.1 - 6e-06 26.3 0.0 0.039 13.9 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 KER30421.1 - 8.7e-06 26.2 0.4 0.88 10.0 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KER30421.1 - 2.2e-05 24.1 0.0 0.39 10.5 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain Rad17 PF03215.15 KER30421.1 - 5.1e-05 23.3 0.1 0.034 14.1 0.0 3.4 4 0 0 4 4 3 1 Rad17 P-loop domain AAA_24 PF13479.6 KER30421.1 - 0.00014 21.6 0.0 0.11 12.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain Spc7 PF08317.11 KER30421.1 - 0.00057 18.9 1.4 0.00057 18.9 1.4 4.2 4 0 0 4 4 4 2 Spc7 kinetochore protein RNA_helicase PF00910.22 KER30421.1 - 0.00091 19.6 0.0 1.1 9.7 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 KER30421.1 - 0.00096 18.9 2.1 0.17 11.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 KER30421.1 - 0.0029 18.1 0.1 0.58 10.7 0.0 4.2 5 0 0 5 5 2 1 AAA domain ADIP PF11559.8 KER30421.1 - 0.01 15.9 0.5 0.01 15.9 0.5 4.0 4 0 0 4 4 1 0 Afadin- and alpha -actinin-Binding T2SSE PF00437.20 KER30421.1 - 0.014 14.5 0.0 5.3 6.0 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.6 KER30421.1 - 0.017 15.0 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KER30421.1 - 0.024 13.9 0.0 1.1 8.5 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KER30421.1 - 0.029 14.1 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein G-alpha PF00503.20 KER30421.1 - 0.045 12.9 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 1 0 G-protein alpha subunit AAA_19 PF13245.6 KER30421.1 - 0.05 13.9 1.2 8.4 6.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KER30421.1 - 0.051 13.5 0.0 1.7 8.5 0.0 3.5 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KER30421.1 - 0.052 13.5 0.1 9.7 6.0 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KER30421.1 - 0.053 14.0 0.0 0.053 14.0 0.0 4.7 5 0 0 5 5 2 0 AAA domain AAA_PrkA PF08298.11 KER30421.1 - 0.055 12.4 0.0 7.6 5.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_25 PF13481.6 KER30421.1 - 0.059 12.9 0.0 7.2 6.1 0.0 3.6 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 KER30421.1 - 0.08 12.1 0.3 9.9 5.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF815) DUF1664 PF07889.12 KER30421.1 - 0.1 12.6 4.5 4 7.5 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SMC_N PF02463.19 KER30421.1 - 0.11 11.9 0.0 20 4.5 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KER30421.1 - 0.15 12.3 3.9 1.3 9.2 0.0 4.0 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 KER30421.1 - 0.16 11.7 0.0 6.3 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Laminin_II PF06009.12 KER30421.1 - 0.3 11.1 13.4 5.6 7.0 8.0 3.1 2 0 0 2 2 2 0 Laminin Domain II HrpB7 PF09486.10 KER30421.1 - 0.31 11.4 33.4 1.6 9.1 4.8 3.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) AAA_33 PF13671.6 KER30421.1 - 0.34 11.1 6.6 3.5 7.8 0.0 4.5 4 0 0 4 4 3 0 AAA domain KxDL PF10241.9 KER30421.1 - 0.46 10.8 5.3 0.15 12.4 0.2 3.0 2 0 0 2 2 1 0 Uncharacterized conserved protein Phage_GP20 PF06810.11 KER30421.1 - 6.4 6.6 12.3 5.8 6.7 1.3 3.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Pkinase PF00069.25 KER30422.1 - 2.4e-43 148.4 0.0 6.3e-40 137.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER30422.1 - 2.5e-15 56.5 0.0 6.7e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Frizzled PF01534.17 KER30423.1 - 0.084 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region HSP70 PF00012.20 KER30424.1 - 1.5e-151 505.6 0.8 3.4e-150 501.1 0.8 2.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER30424.1 - 5.6e-08 32.0 0.0 1.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein ORC5_C PF14630.6 KER30427.1 - 2.8e-47 161.6 0.0 3.8e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KER30427.1 - 5.2e-15 56.2 0.3 1.7e-14 54.5 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER30427.1 - 4.3e-07 30.3 0.0 8.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KER30427.1 - 0.00064 19.0 0.0 0.0009 18.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KER30427.1 - 0.0039 17.1 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KER30427.1 - 0.011 15.6 1.6 0.025 14.5 1.6 1.7 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KER30427.1 - 0.029 14.9 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KER30427.1 - 0.052 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 KER30427.1 - 0.08 12.7 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.9 KER30427.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KER30427.1 - 0.17 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Y_phosphatase PF00102.27 KER30428.1 - 7e-60 202.5 0.1 1.4e-59 201.5 0.1 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KER30428.1 - 0.019 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family VPS11_C PF12451.8 KER30428.1 - 5.9 7.2 6.2 11 6.3 0.1 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal NuA4 PF09340.10 KER30429.1 - 1.1e-24 86.1 0.0 2.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CBM_21 PF03370.13 KER30430.1 - 7.8e-25 87.2 0.1 1.7e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KER30430.1 - 6.1e-10 39.5 0.2 1.4e-09 38.4 0.2 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) 7tm_1 PF00001.21 KER30431.1 - 6.2e-11 42.1 0.0 9.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) BRCT_2 PF16589.5 KER30436.1 - 5.3e-06 26.7 0.0 0.0086 16.5 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KER30436.1 - 0.0009 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KER30436.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain PTCB-BRCT PF12738.7 KER30437.1 - 3e-20 71.9 0.0 5.7e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KER30437.1 - 5.1e-14 52.4 0.1 1.5e-12 47.7 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KER30437.1 - 0.035 14.5 0.0 4.8 7.7 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain BRCT_2 PF16589.5 KER30439.1 - 6.7e-09 36.0 0.0 1.3e-06 28.8 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KER30439.1 - 4.6e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KER30439.1 - 6e-06 26.1 0.4 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain BRCT_3 PF18428.1 KER30439.1 - 0.095 12.8 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KER30439.1 - 0.18 12.1 1.2 0.4 11.0 0.0 2.2 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain RUN PF02759.19 KER30440.1 - 2.6e-11 43.6 0.2 4.5e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 RUN domain PID PF00640.23 KER30440.1 - 1.4e-06 28.3 0.0 6.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ_2 PF13180.6 KER30440.1 - 0.00028 21.2 0.2 0.00054 20.2 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER30440.1 - 0.00069 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.27 KER30441.1 - 2e-51 174.8 0.1 8.2e-51 172.8 0.0 2.0 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PDZ PF00595.24 KER30441.1 - 7.4e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FERM_C PF09380.10 KER30441.1 - 2e-07 31.3 0.2 7.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain Y_phosphatase3 PF13350.6 KER30441.1 - 5.1e-05 23.3 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PDZ_6 PF17820.1 KER30441.1 - 0.00028 20.6 0.0 0.0011 18.7 0.1 2.0 2 0 0 2 2 2 1 PDZ domain DSPc PF00782.20 KER30441.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KER30441.1 - 0.0068 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Rtt106 PF08512.12 KER30443.1 - 0.12 12.8 1.6 1.9e+02 2.5 0.0 4.0 3 1 1 4 4 4 0 Histone chaperone Rttp106-like FERM_M PF00373.18 KER30444.1 - 2.3e-16 60.2 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 KER30444.1 - 3e-13 49.5 0.6 1.2e-12 47.6 0.1 2.1 3 0 0 3 3 3 1 FERM N-terminal domain Ras PF00071.22 KER30445.1 - 1.3e-27 96.4 0.0 1.4e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 KER30445.1 - 0.00091 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KER30445.1 - 0.0015 18.7 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER30445.1 - 0.0018 17.7 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER30445.1 - 0.083 12.8 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Cadherin PF00028.17 KER30447.1 - 4.4e-59 196.9 4.5 1e-14 54.7 0.0 8.5 6 3 1 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 KER30447.1 - 9.1e-06 25.4 3.0 0.41 10.5 0.1 5.5 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 KER30447.1 - 0.14 12.4 0.1 11 6.3 0.0 3.1 3 0 0 3 3 3 0 RET Cadherin like domain 1 Syndecan PF01034.20 KER30447.1 - 0.36 10.8 0.8 0.8 9.7 0.8 1.6 1 0 0 1 1 1 0 Syndecan domain RNA_pol_I_A49 PF06870.12 KER30448.1 - 3.6e-33 115.0 0.2 9.3e-29 100.5 0.1 2.1 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor RVT_1 PF00078.27 KER30448.1 - 0.00046 19.8 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 KER30449.1 - 1.7e-30 106.2 0.1 2.5e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Pao retrotransposon peptidase Jacalin PF01419.17 KER30449.1 - 0.0038 17.1 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain RT_RNaseH_2 PF17919.1 KER30449.1 - 0.045 13.8 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF294_C PF10335.9 KER30449.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain RNA_pol_Rpb1_R PF05001.13 KER30450.1 - 1 9.9 5.4 13 6.4 1.4 3.7 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Nefa_Nip30_N PF10187.9 KER30452.1 - 7.6e-17 61.6 9.6 1.4e-16 60.7 9.6 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 CUB PF00431.20 KER30454.1 - 2e-22 79.6 0.3 7.7e-13 48.7 0.0 4.4 5 1 0 5 5 5 3 CUB domain Ldl_recept_a PF00057.18 KER30454.1 - 0.055 13.7 5.2 0.3 11.3 5.2 2.2 1 1 0 1 1 1 0 Low-density lipoprotein receptor domain class A CUB PF00431.20 KER30455.1 - 2.4e-12 47.2 0.0 2.2e-11 44.1 0.0 2.3 3 0 0 3 3 3 1 CUB domain Herpes_BLLF1 PF05109.13 KER30455.1 - 0.011 13.8 2.5 0.17 9.8 0.0 2.0 1 1 1 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) CUB PF00431.20 KER30456.1 - 5e-13 49.3 0.0 1.1e-10 41.8 0.0 2.1 2 0 0 2 2 2 2 CUB domain AXH PF08517.12 KER30457.1 - 5.7e-19 68.8 0.1 7.3e-14 52.3 0.0 2.6 1 1 1 2 2 2 2 Ataxin-1 and HBP1 module (AXH) DUF4588 PF15251.6 KER30458.1 - 0.0021 17.9 0.2 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Homeodomain PF00046.29 KER30460.1 - 3.5e-12 46.0 0.8 3.5e-12 46.0 0.8 2.9 3 1 1 4 4 4 1 Homeodomain PPP1R32 PF15691.5 KER30461.1 - 2.1e-22 79.8 0.3 2.6e-22 79.5 0.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 Pkinase PF00069.25 KER30462.1 - 3.2e-61 207.0 0.0 6e-39 134.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER30462.1 - 9.8e-28 97.1 0.0 1.2e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KER30462.1 - 8.1e-05 22.7 1.1 0.068 13.1 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER30462.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KER30462.1 - 0.02 14.2 0.1 0.06 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 KER30462.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KER30462.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.24 KER30462.1 - 0.24 12.1 3.3 1.1 10.0 3.3 2.3 1 0 0 1 1 1 0 Protein kinase C terminal domain TP_methylase PF00590.20 KER30463.1 - 1.9e-17 63.9 0.0 4.5e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-Di19 PF05605.12 KER30464.1 - 0.0001 22.5 5.3 0.013 15.8 3.0 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KER30464.1 - 0.01 16.6 7.7 2 9.5 3.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KER30464.1 - 0.33 10.8 2.6 3.8 7.4 0.4 2.4 1 1 1 2 2 2 0 Rad50 zinc hook motif PCI PF01399.27 KER30465.1 - 1.1e-18 67.7 0.4 4.3e-18 65.8 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KER30465.1 - 9.2e-13 48.1 1.3 2e-12 47.0 1.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Takusan PF04822.13 KER30465.1 - 3.4 7.6 13.5 0.67 9.9 0.3 3.7 4 1 0 4 4 4 0 Takusan AMP-binding PF00501.28 KER30467.1 - 6.2e-27 94.3 0.0 1.9e-25 89.4 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme PQQ_2 PF13360.6 KER30467.1 - 2.2e-11 43.8 0.0 0.00044 19.9 0.0 3.5 1 1 3 4 4 4 4 PQQ-like domain Sld5 PF05916.11 KER30467.1 - 2.1e-09 37.8 0.1 3.9e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein PQQ PF01011.21 KER30467.1 - 5.9e-07 29.1 0.0 0.0034 17.3 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 KER30467.1 - 1.1e-06 28.9 0.4 0.25 11.9 0.0 6.4 7 0 0 7 7 7 1 PQQ-like domain PP-binding PF00550.25 KER30467.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site Cep57_MT_bd PF06657.13 KER30468.1 - 0.012 16.0 0.1 0.03 14.7 0.1 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 STAT_int PF02865.17 KER30468.1 - 0.031 14.7 0.4 0.075 13.5 0.4 1.6 1 0 0 1 1 1 0 STAT protein, protein interaction domain Pkinase_Tyr PF07714.17 KER30469.1 - 1.4e-73 247.4 0.0 2.1e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER30469.1 - 8.1e-31 107.3 0.0 1.3e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 KER30469.1 - 5.9e-15 55.1 0.0 1.2e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30469.1 - 1.5e-09 38.3 0.0 9.2e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER30469.1 - 2.2e-08 34.1 0.0 1.4e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER30469.1 - 0.00011 22.4 0.1 0.0023 18.1 0.1 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KER30469.1 - 0.0016 18.7 0.1 4 7.8 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Fz PF01392.22 KER30469.1 - 0.0028 18.3 2.1 0.0028 18.3 2.1 3.1 3 1 0 3 3 3 1 Fz domain ROF PF07073.12 KER30469.1 - 0.078 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) PRIMA1 PF16101.5 KER30469.1 - 2.4 8.2 7.8 6.2 6.9 7.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Prenyltrans PF00432.21 KER30470.1 - 1.3e-20 72.8 10.1 4.5e-07 29.5 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Asparaginase PF00710.20 KER30471.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Asparaginase, N-terminal Asparaginase PF00710.20 KER30472.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Asparaginase, N-terminal Nuc_sug_transp PF04142.15 KER30473.1 - 6.4e-107 357.3 16.7 7.8e-107 357.1 16.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KER30473.1 - 0.0058 16.8 8.4 0.0058 16.8 8.4 2.7 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.6 KER30473.1 - 0.016 14.8 8.7 0.017 14.7 1.0 2.8 2 1 1 3 3 3 0 Putative multidrug resistance efflux transporter PUNUT PF16913.5 KER30473.1 - 0.15 11.3 17.4 0.22 10.7 17.4 1.2 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport S4 PF01479.25 KER30475.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 S4 domain SURF1 PF02104.15 KER30475.1 - 0.083 13.1 0.2 0.4 10.9 0.1 2.0 2 0 0 2 2 2 0 SURF1 family DEAD PF00270.29 KER30477.1 - 6e-56 189.0 0.3 2.4e-43 147.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KER30477.1 - 3.1e-25 88.7 0.0 2e-24 86.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER30477.1 - 3.2e-07 30.5 0.0 4.8e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KER30477.1 - 0.00091 19.5 3.6 0.94 9.8 0.2 3.3 1 1 1 2 2 2 2 AAA domain DUF4407 PF14362.6 KER30477.1 - 0.023 14.1 0.8 0.039 13.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1840 PF08895.11 KER30477.1 - 0.22 11.9 1.0 1.2 9.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Innexin PF00876.18 KER30479.1 - 2.6e-07 30.3 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 KER30480.1 - 8.3e-41 140.4 1.9 1e-40 140.2 1.9 1.1 1 0 0 1 1 1 1 Innexin E1_4HB PF16191.5 KER30481.1 - 0.099 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Dynamin_N PF00350.23 KER30482.1 - 0.031 14.3 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 KER30482.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KER30482.1 - 0.083 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ELM2 PF01448.24 KER30484.1 - 1.6e-06 28.8 0.0 1.8e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 KER30484.1 - 0.00013 21.8 0.2 0.00036 20.4 0.2 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KER30484.1 - 0.001 19.2 0.3 0.0088 16.2 0.0 2.7 4 0 0 4 4 4 1 Myb-like DNA-binding domain fn3 PF00041.21 KER30486.1 - 0 1308.6 139.7 1.9e-16 60.2 0.1 57.0 58 0 0 58 58 57 48 Fibronectin type III domain I-set PF07679.16 KER30486.1 - 0 1069.4 0.0 6.8e-18 64.5 0.0 39.6 39 1 0 39 39 39 31 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30486.1 - 7e-229 741.1 0.0 4.2e-12 46.5 0.0 36.4 34 1 1 35 35 35 30 Immunoglobulin domain ig PF00047.25 KER30486.1 - 2.3e-102 335.3 0.0 8.2e-10 38.7 0.1 33.7 35 0 0 35 35 34 15 Immunoglobulin domain Ig_2 PF13895.6 KER30486.1 - 2.6e-78 258.4 0.0 2.5e-09 37.3 0.1 28.5 32 0 0 32 32 31 11 Immunoglobulin domain V-set PF07686.17 KER30486.1 - 4.2e-67 223.2 0.0 1.3e-05 25.3 0.0 35.2 34 6 0 34 34 33 7 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 KER30486.1 - 1.3e-53 179.5 60.0 0.069 13.7 0.0 39.8 42 1 1 43 43 41 9 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 KER30486.1 - 2.4e-34 117.4 15.3 0.01 15.7 0.0 16.3 19 0 0 19 19 16 9 Tissue factor SusE PF14292.6 KER30486.1 - 2.4e-33 114.6 22.4 0.23 11.7 0.2 21.4 22 2 2 24 24 22 8 SusE outer membrane protein C2-set_2 PF08205.12 KER30486.1 - 2.9e-17 62.5 17.9 0.056 13.5 0.0 15.1 20 0 0 20 20 17 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 KER30486.1 - 1.7e-15 56.8 2.9 0.6 10.2 0.0 14.7 18 0 0 18 18 16 1 Penicillin-Binding Protein C-terminus Family Interfer-bind PF09294.10 KER30486.1 - 2.2e-11 44.0 1.0 26 5.2 0.0 14.0 15 0 0 15 15 15 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase PF00069.25 KER30486.1 - 2.5e-11 43.5 0.3 6.3e-06 25.7 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain DUF2369 PF10179.9 KER30486.1 - 6.5e-11 42.5 0.0 6.5 7.2 0.0 11.3 11 0 0 11 11 11 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 KER30486.1 - 3.3e-06 27.5 12.1 48 4.6 0.0 14.8 21 0 0 21 21 16 0 PhoD-like phosphatase, N-terminal domain EpoR_lig-bind PF09067.10 KER30486.1 - 0.00011 22.4 5.9 53 4.1 0.0 7.1 7 0 0 7 7 7 0 Erythropoietin receptor, ligand binding Izumo-Ig PF16706.5 KER30486.1 - 0.00014 21.9 2.2 41 4.3 0.0 8.8 8 0 0 8 8 7 0 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KER30486.1 - 0.0037 16.1 1.1 35 3.0 0.0 7.0 9 0 0 9 9 9 0 Alphaherpesvirus glycoprotein E PilX PF13681.6 KER30486.1 - 0.011 16.1 1.4 0.9 10.0 0.0 5.4 5 0 0 5 5 2 0 Type IV pilus assembly protein PilX C-term DUF3869 PF12985.7 KER30486.1 - 0.027 14.9 6.3 3e+02 1.8 0.0 6.8 7 0 0 7 7 7 0 Domain of unknown function (DUF3869) DUF2540 PF10802.8 KER30486.1 - 0.15 12.1 15.6 16 5.6 0.1 6.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2540) MBG PF17883.1 KER30486.1 - 0.6 10.7 9.8 80 3.9 0.0 6.9 6 0 0 6 6 6 0 MBG domain CBP_BcsO PF17037.5 KER30487.1 - 2.4 8.3 19.4 0.57 10.3 0.2 5.0 5 0 0 5 5 5 0 Cellulose biosynthesis protein BcsO LRS4 PF10422.9 KER30487.1 - 3.7 7.0 7.2 0.69 9.4 1.1 2.7 3 2 1 4 4 4 0 Monopolin complex subunit LRS4 I-set PF07679.16 KER30488.1 - 2.7e-146 476.0 11.8 1.2e-13 50.9 0.0 13.8 13 0 0 13 13 13 13 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30488.1 - 1.3e-113 371.7 2.4 1.6e-09 38.2 0.0 13.7 13 0 0 13 13 13 12 Immunoglobulin domain ig PF00047.25 KER30488.1 - 2.6e-60 200.6 7.2 1.4e-06 28.4 0.0 12.5 12 0 0 12 12 12 11 Immunoglobulin domain Ig_2 PF13895.6 KER30488.1 - 1.4e-51 172.8 0.0 0.00017 21.9 0.0 13.1 13 0 0 13 13 13 11 Immunoglobulin domain V-set PF07686.17 KER30488.1 - 1.2e-45 154.1 0.0 0.0014 18.8 0.0 13.1 13 1 0 13 13 13 11 Immunoglobulin V-set domain fn3 PF00041.21 KER30488.1 - 1e-16 61.0 3.8 2.4e-08 34.2 0.2 3.5 3 0 0 3 3 3 2 Fibronectin type III domain Izumo-Ig PF16706.5 KER30488.1 - 7.7e-13 48.3 0.2 8.5 6.5 0.0 10.1 11 0 0 11 11 10 2 Izumo-like Immunoglobulin domain C1-set PF07654.15 KER30488.1 - 3.3e-12 46.6 14.5 0.69 10.3 0.0 10.2 10 0 0 10 10 10 2 Immunoglobulin C1-set domain BiPBP_C PF06832.12 KER30488.1 - 2.5e-08 33.9 2.2 12 6.0 0.0 8.9 10 0 0 10 10 9 1 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 KER30488.1 - 4.2e-05 23.5 5.0 1.7 8.7 0.0 7.9 10 0 0 10 10 10 1 CD80-like C2-set immunoglobulin domain DUF3222 PF11519.8 KER30488.1 - 5.3 7.4 4.9 2e+02 2.3 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3222) I-set PF07679.16 KER30489.1 - 1.6e-26 92.2 10.2 1.8e-09 37.5 0.3 3.5 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30489.1 - 6.4e-19 68.3 10.0 1.1e-06 29.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KER30489.1 - 3.6e-06 27.0 8.0 4.7e-05 23.5 0.0 3.8 3 1 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 KER30489.1 - 2.2e-05 24.7 0.6 0.00081 19.7 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin domain IFP_35_N PF07334.13 KER30489.1 - 0.33 11.0 8.6 12 6.0 0.4 4.0 3 2 2 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Big_2 PF02368.18 KER30489.1 - 7.7 6.5 17.8 1.8 8.5 0.9 4.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 2) I-set PF07679.16 KER30490.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30490.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30490.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30490.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30491.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30491.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30491.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30491.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30492.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30492.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30492.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30492.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30493.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30493.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30493.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30493.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30494.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30494.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30494.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30494.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30495.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30495.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30495.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30495.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30496.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30496.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30496.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30496.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30497.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30497.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30497.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30497.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30498.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30498.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30498.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30498.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30499.1 - 1.4e-11 44.3 2.5 4.7e-10 39.4 0.3 2.7 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30499.1 - 3e-08 34.1 3.6 1.2e-05 25.8 0.5 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IFP_35_N PF07334.13 KER30499.1 - 0.31 11.1 2.2 4.8 7.3 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ig PF00047.25 KER30499.1 - 0.81 9.9 3.8 19 5.5 0.3 2.7 3 1 0 3 3 3 0 Immunoglobulin domain I-set PF07679.16 KER30500.1 - 7.3e-299 965.1 0.0 3.2e-20 72.0 0.0 22.4 22 1 0 22 22 22 20 Immunoglobulin I-set domain Ig_3 PF13927.6 KER30500.1 - 3.7e-215 697.1 27.0 5.5e-15 55.7 0.0 22.1 22 0 0 22 22 22 20 Immunoglobulin domain ig PF00047.25 KER30500.1 - 1.7e-105 345.4 10.1 5.2e-09 36.2 0.0 20.8 21 0 0 21 21 20 16 Immunoglobulin domain Ig_2 PF13895.6 KER30500.1 - 1.1e-104 342.8 12.9 4.3e-10 39.8 0.0 20.8 20 1 0 20 20 20 16 Immunoglobulin domain V-set PF07686.17 KER30500.1 - 2.3e-35 121.0 19.0 0.077 13.2 0.0 23.1 20 7 1 21 21 21 6 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER30500.1 - 5.5e-27 93.7 30.2 0.083 13.0 0.0 19.2 20 0 0 20 20 20 6 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KER30500.1 - 2.2e-12 47.2 10.3 1 9.7 0.0 11.5 13 0 0 13 13 13 3 Immunoglobulin C1-set domain Ig_6 PF18452.1 KER30500.1 - 2.4e-12 46.2 0.6 0.62 9.7 0.0 8.6 10 0 0 10 10 10 3 Immunoglobulin domain Spectrin PF00435.21 KER30500.1 - 3.8e-08 33.8 34.2 0.00017 22.0 0.4 7.2 6 1 0 6 6 5 3 Spectrin repeat Izumo-Ig PF16706.5 KER30500.1 - 1.2e-06 28.5 1.6 8.7 6.5 0.0 7.9 9 0 0 9 9 8 1 Izumo-like Immunoglobulin domain SKA2 PF16740.5 KER30500.1 - 0.11 12.2 5.5 1.1 9.1 5.5 2.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AMP-binding_C_2 PF14535.6 KER30500.1 - 0.3 11.4 1.6 4.5 7.7 0.0 3.9 3 1 1 4 4 4 0 AMP-binding enzyme C-terminal domain AKNA PF12443.8 KER30500.1 - 0.66 10.7 4.2 0.58 10.8 0.1 2.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor BLOC1_2 PF10046.9 KER30500.1 - 2.8 8.3 6.9 1.4 9.3 0.2 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CortBP2 PF09727.9 KER30500.1 - 3.2 7.6 9.5 0.51 10.2 5.3 1.8 2 0 0 2 2 2 0 Cortactin-binding protein-2 DUF4600 PF15372.6 KER30500.1 - 3.7 8.0 6.4 1.9 8.9 2.9 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4600) Vps23_core PF09454.10 KER30501.1 - 4.5e-19 68.2 0.2 8.5e-19 67.3 0.2 1.5 1 0 0 1 1 1 1 Vps23 core domain ATG16 PF08614.11 KER30501.1 - 0.0019 18.5 4.7 0.0044 17.3 4.7 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KER30501.1 - 0.006 17.1 10.2 0.006 17.1 10.2 1.7 2 0 0 2 2 1 1 Apg6 coiled-coil region ISG65-75 PF11727.8 KER30501.1 - 0.009 15.3 2.7 0.019 14.2 2.7 1.5 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF812 PF05667.11 KER30501.1 - 0.014 14.3 6.7 0.025 13.5 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.19 KER30501.1 - 0.015 15.2 9.9 0.015 15.2 9.9 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Nckap1 PF09735.9 KER30501.1 - 0.028 12.4 0.6 0.039 11.9 0.6 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein RasGAP_C PF03836.15 KER30501.1 - 0.031 14.4 5.2 0.09 12.9 5.2 1.7 1 0 0 1 1 1 0 RasGAP C-terminus FapA PF03961.13 KER30501.1 - 0.034 12.8 5.2 0.06 11.9 5.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1707 PF08044.11 KER30501.1 - 0.044 13.8 0.1 0.19 11.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Aminopep PF10023.9 KER30501.1 - 0.077 12.3 2.2 0.12 11.7 2.2 1.3 1 0 0 1 1 1 0 Putative aminopeptidase CEP209_CC5 PF16574.5 KER30501.1 - 0.12 12.5 9.0 0.29 11.3 5.5 2.6 3 0 0 3 3 3 0 Coiled-coil region of centrosome protein CE290 TSKS PF15358.6 KER30501.1 - 0.14 10.5 4.5 0.076 11.4 1.4 1.8 2 0 0 2 2 2 0 Testis-specific serine kinase substrate Jnk-SapK_ap_N PF09744.9 KER30501.1 - 0.17 12.1 10.5 0.41 10.9 10.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 COG5 PF10392.9 KER30501.1 - 0.18 12.0 3.2 0.5 10.5 3.2 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CREPT PF16566.5 KER30501.1 - 0.34 11.1 6.3 0.57 10.4 4.4 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TMF_DNA_bd PF12329.8 KER30501.1 - 0.38 10.8 17.5 0.14 12.2 13.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KER30501.1 - 0.44 9.7 1.7 0.76 9.0 1.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 KER30501.1 - 0.82 8.9 9.1 1.5 8.0 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KER30501.1 - 1 9.9 5.4 20 5.8 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc24 PF08286.11 KER30501.1 - 1 9.6 5.7 3.9 7.8 5.7 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 KER30501.1 - 1.6 8.2 7.7 0.64 9.5 4.9 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2203 PF09969.9 KER30501.1 - 1.7 9.4 6.2 0.61 10.8 2.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tho2 PF11262.8 KER30501.1 - 2 7.5 7.6 0.5 9.5 4.1 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3987 PF13148.6 KER30501.1 - 3.2 6.7 6.0 7.1 5.5 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1366 PF07104.11 KER30501.1 - 3.5 7.3 5.9 5 6.8 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Vac_ImportDeg PF09783.9 KER30502.1 - 1.4e-55 187.5 0.2 2.3e-55 186.9 0.2 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ribosomal_S4e PF00900.20 KER30503.1 - 1.7e-36 124.0 0.2 1.7e-36 124.0 0.2 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KER30503.1 - 1.8e-25 88.3 0.2 3.4e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KER30503.1 - 1.4e-20 73.0 6.1 1.9e-20 72.7 4.8 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KER30503.1 - 5.6e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KER30503.1 - 5.1e-05 23.1 0.0 0.0002 21.2 0.0 2.0 1 0 0 1 1 1 1 KOW motif Sipho_tail PF05709.11 KER30503.1 - 0.06 12.7 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 Phage tail protein DUF5072 PF16807.5 KER30503.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) Tetraspanin PF00335.20 KER30504.1 - 8.4e-40 136.9 9.2 1.1e-39 136.6 9.2 1.1 1 0 0 1 1 1 1 Tetraspanin family TMEM132D_C PF15706.5 KER30504.1 - 0.15 11.8 2.6 4.7 7.0 0.0 3.0 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Wzy_C PF04932.15 KER30504.1 - 0.55 9.8 6.2 14 5.3 0.0 3.5 3 1 0 3 3 3 0 O-Antigen ligase Claudin_2 PF13903.6 KER30504.1 - 6.6 6.4 13.4 16 5.2 8.8 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Glu_synthase PF01645.17 KER30505.1 - 3.5e-150 500.2 0.3 5.2e-148 493.1 0.1 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.21 KER30505.1 - 1.2e-148 495.3 0.0 3.1e-78 263.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 KER30505.1 - 6.3e-105 350.6 0.0 3e-103 345.1 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KER30505.1 - 3.3e-71 238.8 0.5 6.5e-71 237.9 0.5 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KER30505.1 - 4.1e-32 111.6 0.0 2.3e-23 82.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KER30505.1 - 1.5e-21 76.2 0.1 3.5e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 KER30505.1 - 8.8e-11 42.2 3.3 5.6e-08 33.2 0.4 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KER30505.1 - 5.7e-09 36.1 0.7 1.8e-08 34.5 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KER30505.1 - 7.9e-08 32.3 0.2 0.00021 21.0 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KER30505.1 - 1.4e-07 31.1 0.0 0.00016 21.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KER30505.1 - 5.8e-07 29.2 2.3 6.9e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KER30505.1 - 1e-06 27.7 0.8 1.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KER30505.1 - 1.7e-06 27.6 0.1 3.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KER30505.1 - 1.2e-05 24.7 0.1 6.1e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KER30505.1 - 4.2e-05 22.8 0.1 4.2e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KER30505.1 - 5.9e-05 23.5 0.2 0.062 13.7 0.0 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KER30505.1 - 0.0011 18.3 0.3 0.003 16.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KER30505.1 - 0.0058 16.0 0.3 3 7.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 KER30505.1 - 0.0073 15.4 0.4 0.062 12.3 0.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ApbA PF02558.16 KER30505.1 - 0.0088 15.7 0.4 0.028 14.1 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KER30505.1 - 0.011 14.8 0.4 0.062 12.3 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 KER30505.1 - 0.018 13.5 0.1 1.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KER30505.1 - 0.027 13.5 1.1 0.52 9.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KER30505.1 - 0.029 14.4 0.1 0.36 10.8 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KER30505.1 - 0.037 13.4 0.1 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KER30505.1 - 0.047 14.0 1.1 0.21 11.9 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.21 KER30505.1 - 0.053 13.6 0.2 8.2 6.5 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 KER30505.1 - 0.1 13.2 1.7 0.92 10.1 0.1 3.1 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KER30505.1 - 0.12 11.1 0.3 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 KER30505.1 - 0.13 11.4 0.0 7.3 5.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SF-assemblin PF06705.11 KER30508.1 - 0.0016 17.9 2.6 0.3 10.4 0.4 2.1 2 0 0 2 2 2 2 SF-assemblin/beta giardin FAD_binding_2 PF00890.24 KER30508.1 - 0.13 11.3 0.0 8.9 5.3 0.0 2.0 1 1 0 2 2 2 0 FAD binding domain ArfGap PF01412.18 KER30508.1 - 4.4 7.4 9.6 14 5.8 0.3 2.9 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf Peptidase_M16_M PF16187.5 KER30509.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 Malic_M PF03949.15 KER30511.1 - 9.7e-89 297.0 0.1 1.6e-88 296.4 0.1 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KER30511.1 - 1.1e-77 259.9 0.0 1.8e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MAM1 PF10434.9 KER30513.1 - 0.03 13.9 0.2 0.036 13.7 0.2 1.0 1 0 0 1 1 1 0 Monopolin complex protein MAM1 zf-H2C2_2 PF13465.6 KER30514.1 - 1.4e-24 85.3 42.1 1.9e-08 34.4 0.6 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 KER30514.1 - 2.5e-19 68.6 44.5 1.1e-05 25.6 0.6 7.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER30514.1 - 2e-12 46.8 34.8 0.0053 17.5 0.6 6.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KER30514.1 - 5.4e-08 33.0 24.2 0.072 13.5 1.6 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KER30514.1 - 1.2e-05 25.1 33.2 0.0022 17.9 1.7 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER30514.1 - 0.00013 22.2 26.0 0.037 14.3 0.3 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KER30514.1 - 0.029 14.7 19.8 0.65 10.4 11.6 4.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 KER30514.1 - 0.054 13.8 0.6 6.7 7.1 0.0 3.2 1 1 2 3 3 3 0 BolA-like protein Zn-ribbon_8 PF09723.10 KER30514.1 - 0.11 12.7 10.3 18 5.5 0.6 4.3 2 1 1 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 KER30514.1 - 0.12 12.6 15.1 0.62 10.3 3.0 3.8 2 1 0 3 3 3 0 TFIIH C1-like domain zf-BED PF02892.15 KER30514.1 - 0.87 9.7 15.3 1.2e+03 -0.3 14.5 3.7 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 KER30514.1 - 2 8.3 16.9 0.089 12.6 1.8 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KER30514.1 - 4.4 7.2 15.8 2.3 8.1 0.3 5.1 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KER30514.1 - 6.6 6.6 8.8 9.7 6.1 0.3 3.9 1 1 2 4 4 4 0 GAGA factor DUF4428 PF14471.6 KER30514.1 - 6.7 6.7 6.3 13 5.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) Sulfotransfer_4 PF17784.1 KER30515.1 - 4.6e-50 170.4 0.2 3.5e-49 167.5 0.2 1.9 1 1 0 1 1 1 1 Sulfotransferase domain EIF_2_alpha PF07541.12 KER30516.1 - 2.7e-32 111.3 0.0 5.9e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KER30516.1 - 1.4e-12 47.8 1.2 2.3e-12 47.1 1.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 KER30516.1 - 0.027 15.1 0.5 0.076 13.6 0.5 1.9 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF4453 PF14627.6 KER30516.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Astro_capsid_p PF12226.8 KER30516.1 - 2.1 7.4 8.0 3.4 6.7 8.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 KER30516.1 - 3.5 6.6 7.7 2.9 6.8 6.2 1.6 2 0 0 2 2 2 0 Pes-10 Cytadhesin_P30 PF07271.11 KER30517.1 - 0.076 12.6 6.1 0.11 12.1 6.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Mac-1 PF09028.10 KER30518.1 - 0.04 13.0 0.1 0.047 12.8 0.1 1.0 1 0 0 1 1 1 0 Mac 1 DUF4029 PF13221.6 KER30520.1 - 0.052 14.2 0.7 0.084 13.5 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) DUF4579 PF15158.6 KER30520.1 - 0.25 11.1 1.1 0.32 10.7 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4579) STE2 PF02116.15 KER30521.1 - 0.0028 17.0 5.8 0.0033 16.8 5.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF4064 PF13273.6 KER30521.1 - 0.14 12.4 7.8 0.094 13.0 5.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 KER30521.1 - 0.42 9.3 3.0 0.46 9.2 3.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amidase PF01425.21 KER30522.1 - 1.8e-81 274.4 0.0 2.7e-81 273.8 0.0 1.2 1 0 0 1 1 1 1 Amidase DoxX_2 PF13564.6 KER30523.1 - 1.5e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 KER30523.1 - 1.1e-05 25.9 0.4 2e-05 25.1 0.4 1.4 1 0 0 1 1 1 1 DoxX DUF308 PF03729.13 KER30523.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.9 3 1 1 4 4 4 0 Short repeat of unknown function (DUF308) Epimerase PF01370.21 KER30525.1 - 5.2e-51 173.4 0.0 6.8e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KER30525.1 - 9.7e-09 35.1 0.4 2.4e-08 33.8 0.4 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KER30525.1 - 0.00011 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KER30525.1 - 0.013 14.6 1.4 0.023 13.8 0.0 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein AbiTii PF18864.1 KER30527.1 - 0.077 13.1 0.0 0.077 13.1 0.0 1.0 1 0 0 1 1 1 0 AbiTii DnaJ_C PF01556.18 KER30528.1 - 1.8e-39 135.2 0.0 2.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KER30528.1 - 7.3e-21 74.1 0.4 1.3e-20 73.3 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain PNISR PF15996.5 KER30532.1 - 3.5e-42 145.0 0.5 3.5e-42 145.0 0.5 3.1 2 1 0 2 2 2 1 Arginine/serine-rich protein PNISR BK_channel_a PF03493.18 KER30533.1 - 6.5e-21 74.4 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 KER30533.1 - 3.8e-14 52.4 2.0 1e-13 51.0 2.0 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KER30533.1 - 2.1e-07 30.4 7.3 2.4e-06 27.0 7.3 2.4 3 0 0 3 3 3 1 Ion transport protein TrkA_N PF02254.18 KER30533.1 - 0.028 14.7 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain MPP6 PF10175.9 KER30535.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.6 1 1 0 1 1 1 1 M-phase phosphoprotein 6 SRAP PF02586.14 KER30536.1 - 1.3e-43 149.2 0.0 3.7e-38 131.3 0.0 2.3 1 1 1 2 2 2 2 SOS response associated peptidase (SRAP) Baculo_LEF-3 PF05847.11 KER30536.1 - 0.029 13.6 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) KGK PF08872.10 KER30536.1 - 0.11 13.0 0.1 9.5 6.7 0.1 2.3 2 0 0 2 2 2 0 KGK domain Pkinase_Tyr PF07714.17 KER30537.1 - 1.8e-70 237.2 0.0 2.4e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER30537.1 - 4e-43 147.7 0.0 6.2e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KER30539.1 - 5.6e-27 94.7 0.0 1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30539.1 - 1.3e-17 63.9 0.0 2.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER30539.1 - 9.7e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FHA PF00498.26 KER30540.1 - 4.2e-07 30.2 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain SOCS_box PF07525.16 KER30542.1 - 4.6e-06 26.9 0.5 1.2e-05 25.5 0.5 1.8 1 0 0 1 1 1 1 SOCS box PLAC PF08686.11 KER30543.1 - 2.4 9.0 11.5 0.28 12.0 6.8 1.9 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain Arm PF00514.23 KER30544.1 - 5.8e-60 197.6 20.2 9.2e-10 38.2 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KER30544.1 - 9.5e-18 64.4 8.6 9.5e-18 64.4 8.6 1.9 3 0 0 3 3 3 1 Importin beta binding domain Arm_3 PF16186.5 KER30544.1 - 4.5e-17 61.3 1.2 2e-16 59.2 1.8 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 KER30544.1 - 2.2e-12 47.2 3.3 0.0023 18.4 0.1 5.3 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 KER30544.1 - 6.1e-10 39.4 5.8 0.017 15.5 0.0 6.9 3 1 7 10 10 10 4 HEAT repeats HEAT PF02985.22 KER30544.1 - 1.4e-06 28.1 14.7 0.11 12.8 0.0 7.9 9 0 0 9 9 9 2 HEAT repeat NopRA1 PF16201.5 KER30544.1 - 2.6e-06 27.2 0.1 0.029 13.9 0.0 3.6 2 1 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Arm_2 PF04826.13 KER30544.1 - 4.9e-05 22.9 0.1 0.29 10.6 0.1 3.1 2 1 0 2 2 2 2 Armadillo-like Taxilin PF09728.9 KER30544.1 - 0.16 11.1 5.5 0.25 10.5 5.5 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1955 PF09205.10 KER30544.1 - 0.43 10.3 4.8 2.6 7.8 0.1 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF1955) Baculo_PEP_C PF04513.12 KER30545.1 - 0.0028 17.7 12.0 1.6 8.8 0.1 5.2 4 2 2 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad3 PF08656.10 KER30545.1 - 0.0085 16.2 11.3 14 5.8 0.1 5.8 5 2 0 5 5 5 1 DASH complex subunit Dad3 DUF4407 PF14362.6 KER30545.1 - 0.11 11.9 7.5 1.2 8.4 0.3 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KER30545.1 - 0.42 10.9 12.5 0.45 10.8 0.4 4.8 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 KER30545.1 - 0.55 10.7 3.9 8 6.9 0.1 3.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SOGA PF11365.8 KER30545.1 - 0.97 10.6 6.7 0.43 11.7 0.5 3.3 2 1 0 2 2 2 0 Protein SOGA DUF2730 PF10805.8 KER30545.1 - 5.1 7.2 8.5 1.3 9.2 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 KER30545.1 - 6.3 6.9 19.1 6.1 6.9 1.4 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 KER30546.1 - 1.6e-17 63.1 0.6 1.8e-17 62.9 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2909 PF11137.8 KER30546.1 - 0.0014 18.5 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) DUF2970 PF11174.8 KER30546.1 - 0.017 14.9 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Use1 PF09753.9 KER30546.1 - 0.027 14.2 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF5345 PF17280.2 KER30546.1 - 0.05 13.6 0.5 0.072 13.1 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5345) GET2 PF08690.10 KER30546.1 - 0.052 13.2 0.0 0.055 13.1 0.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Sec20 PF03908.13 KER30546.1 - 0.07 13.1 0.2 0.1 12.5 0.2 1.3 1 1 0 1 1 1 0 Sec20 MCU PF04678.13 KER30546.1 - 0.071 13.2 0.2 0.082 13.0 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DotU PF09850.9 KER30546.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF2207 PF09972.9 KER30546.1 - 0.12 11.2 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rax2 PF12768.7 KER30546.1 - 0.12 11.8 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TGF_beta PF00019.20 KER30547.1 - 1.4e-11 45.3 1.8 2.7e-11 44.3 1.8 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain RhoGAP PF00620.27 KER30548.1 - 9.1e-40 136.0 0.0 1.5e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KER30548.1 - 0.033 14.7 0.1 0.34 11.5 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF2721 PF11026.8 KER30549.1 - 0.87 9.5 11.3 0.04 13.8 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) UL45 PF05473.12 KER30549.1 - 4 7.0 8.8 1.5 8.4 1.2 2.4 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-C4pol PF14260.6 KER30551.1 - 0.037 14.5 0.4 0.045 14.2 0.4 1.2 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DHHC PF01529.20 KER30552.1 - 1.4 9.0 6.1 1.6 8.8 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2207 PF09972.9 KER30552.1 - 1.9 7.1 7.4 1.1 7.9 5.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-LITAF-like PF10601.9 KER30552.1 - 2.7 8.3 6.4 1.4 9.2 3.7 2.0 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Rsm22 PF09243.10 KER30553.1 - 1.2e-35 123.1 0.0 5.9e-32 111.0 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KER30553.1 - 0.048 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VPS53_C PF16854.5 KER30554.1 - 0.11 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus CH PF00307.31 KER30556.1 - 1.8e-23 82.8 0.1 2.9e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 KER30556.1 - 1.4e-10 40.6 4.6 2.2e-10 39.9 4.6 1.4 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.8 KER30556.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.11 KER30556.1 - 0.067 13.5 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 CDC24 Calponin MutS_V PF00488.21 KER30558.1 - 1.7e-71 240.1 0.0 3.5e-71 239.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KER30558.1 - 2.2e-25 90.0 0.0 2e-24 86.9 0.0 2.4 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KER30558.1 - 1.7e-12 47.5 0.5 2e-09 37.7 0.1 2.5 2 0 0 2 2 2 2 MutS family domain IV MutS_II PF05188.17 KER30558.1 - 8.6e-12 45.5 0.0 2.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II PDDEXK_7 PF04411.12 KER30558.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Synaptonemal_3 PF15191.6 KER30561.1 - 0.0085 15.8 1.1 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 Synaptonemal complex central element protein 3 zf-C2H2 PF00096.26 KER30562.1 - 2.5e-18 65.4 38.9 0.00024 21.4 0.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER30562.1 - 5.4e-12 45.5 40.2 0.0052 17.5 0.1 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER30562.1 - 1.5e-11 44.2 13.7 0.0061 16.8 0.0 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KER30562.1 - 1.9e-11 43.9 35.6 3.6e-06 27.1 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER30562.1 - 1.2e-05 25.2 29.8 0.037 14.1 0.3 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HE PF16278.5 KER30562.1 - 0.0012 19.2 23.0 0.46 11.0 0.8 5.5 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KER30562.1 - 0.0043 17.4 29.3 0.42 11.1 0.1 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KER30562.1 - 0.64 10.0 6.6 3.5 7.6 0.2 3.8 3 1 1 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KER30562.1 - 2.2 8.7 20.8 0.39 11.1 0.2 5.0 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Ta0938 PF11494.8 KER30562.1 - 3.9 7.8 5.2 19 5.6 0.3 2.7 1 1 1 2 2 2 0 Ta0938 zf_ZIC PF18366.1 KER30562.1 - 6.8 6.9 15.8 24 5.1 0.0 4.6 4 1 1 5 5 5 0 Zic proteins zinc finger domain LIM PF00412.22 KER30566.1 - 3e-19 69.0 13.8 1.8e-10 40.9 0.8 3.9 4 0 0 4 4 4 3 LIM domain CM_1 PF07736.11 KER30566.1 - 0.051 14.0 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 Chorismate mutase type I DZR PF12773.7 KER30566.1 - 1.2 9.2 16.2 7.3e+03 -2.9 16.2 3.5 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KER30566.1 - 5.2 6.9 11.6 8.9 6.2 0.1 4.2 3 1 2 5 5 5 0 zinc-ribbon domain Ribosomal_L7Ae PF01248.26 KER30567.1 - 9.3e-21 73.4 0.0 1.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 KER30567.1 - 0.033 14.3 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 KER30568.1 - 1.4e-28 98.9 0.1 1.7e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KER30568.1 - 1.4e-05 25.5 0.2 0.00013 22.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KER30568.1 - 2.5e-05 24.5 0.0 0.0015 18.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KER30568.1 - 0.00092 18.6 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KER30568.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KER30568.1 - 0.0027 17.5 0.0 0.0031 17.4 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 KER30568.1 - 0.0053 16.5 0.0 0.0084 15.9 0.0 1.4 1 1 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 KER30568.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KER30568.1 - 0.024 14.3 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Redoxin Phosducin PF02114.16 KER30568.1 - 0.028 13.4 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 Phosducin HyaE PF07449.11 KER30568.1 - 0.057 13.4 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE FSIP1 PF15554.6 KER30569.1 - 1e-06 28.1 22.9 6.2e-05 22.3 0.6 3.2 3 1 0 3 3 3 2 FSIP1 family DUF4770 PF15994.5 KER30569.1 - 0.42 10.8 5.6 0.062 13.6 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Glyco_transf_7N PF13733.6 KER30570.1 - 1.6e-42 144.4 0.0 2.6e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KER30570.1 - 1.3e-25 88.8 1.1 2.9e-25 87.7 1.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ig_3 PF13927.6 KER30573.1 - 9.7e-11 42.1 0.0 3.4e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER30573.1 - 6.5e-09 35.7 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER30573.1 - 5.4e-06 26.7 0.0 1.6e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER30573.1 - 2.4e-05 24.4 0.0 6.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER30573.1 - 0.014 15.5 0.1 2.2 8.5 0.1 2.6 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 KER30573.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Porphobil_deam PF01379.20 KER30576.1 - 1.5e-73 246.7 0.1 2e-73 246.3 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KER30576.1 - 5.5e-10 39.5 0.0 2.3e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain THUMP PF02926.17 KER30577.1 - 0.0069 16.5 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 THUMP domain Dna2 PF08696.11 KER30577.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 Bcl-2 PF00452.19 KER30580.1 - 1.9e-16 60.5 0.3 3.2e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Runt PF00853.19 KER30582.1 - 5.5e-38 129.4 0.0 6.2e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 Runt domain eIF2_C PF09173.11 KER30584.1 - 1.8e-36 124.2 0.4 5.5e-36 122.7 0.4 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KER30584.1 - 1.1e-23 83.8 2.9 7.5e-23 81.1 2.9 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KER30584.1 - 5.9e-10 39.4 0.2 1.5e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KER30584.1 - 0.00076 19.4 0.3 0.0028 17.6 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KER30584.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KER30584.1 - 0.025 14.6 1.5 0.052 13.6 0.1 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 KER30584.1 - 0.074 12.8 1.0 8.3 6.2 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Chordopox_A13L PF05961.11 KER30585.1 - 0.049 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein stn_TNFRSF12A PF12191.8 KER30585.1 - 0.051 13.8 0.7 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM132D_C PF15706.5 KER30585.1 - 0.14 12.0 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pou PF00157.17 KER30586.1 - 1.5e-20 72.9 0.6 4.6e-14 52.2 0.0 2.6 2 0 0 2 2 2 2 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KER30586.1 - 1.6e-13 50.3 0.3 4.1e-13 49.0 0.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER30586.1 - 4e-05 23.4 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Y_phosphatase PF00102.27 KER30588.1 - 1.9e-43 148.7 0.0 1.2e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KER30588.1 - 0.0027 17.7 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KER30588.1 - 0.0041 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PsaX PF08078.12 KER30588.1 - 0.49 10.4 2.9 0.87 9.6 2.9 1.4 1 0 0 1 1 1 0 PsaX family GARP PF16731.5 KER30591.1 - 0.57 9.8 4.9 2.4 7.8 4.9 2.1 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma zf-HC5HC2H PF13771.6 KER30592.1 - 3.8e-14 52.7 3.5 3.8e-14 52.7 3.5 1.6 1 1 1 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KER30592.1 - 1.3e-05 25.3 7.3 2.5e-05 24.4 6.6 1.8 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-C2H2_10 PF16588.5 KER30592.1 - 0.22 11.3 0.3 0.22 11.3 0.3 2.9 3 0 0 3 3 3 0 C2H2 zinc-finger Na_H_antiport_1 PF06965.12 KER30593.1 - 0.068 12.0 0.0 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Cytochrom_B561 PF03188.16 KER30594.1 - 3.5e-32 111.4 5.5 3.5e-32 111.4 5.5 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KER30594.1 - 7.4e-05 22.5 2.1 7.4e-05 22.5 2.1 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.20 KER30594.1 - 0.00057 19.5 11.7 0.0021 17.7 6.8 2.4 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 Ferric_reduct PF01794.19 KER30594.1 - 0.0076 16.4 10.9 0.087 12.9 6.7 2.6 2 1 0 2 2 2 2 Ferric reductase like transmembrane component DUF4079 PF13301.6 KER30594.1 - 0.031 14.4 4.1 0.11 12.7 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 KER30595.1 - 2.2e-34 118.5 5.7 2.2e-34 118.5 5.7 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KER30595.1 - 6.4e-05 22.7 6.0 6.4e-05 22.7 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF202 PF02656.15 KER30595.1 - 2 8.9 13.4 5.5 7.5 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ni_hydr_CYTB PF01292.20 KER30595.1 - 2.1 7.9 21.6 13 5.3 21.8 1.9 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 KER30595.1 - 6.7 6.9 14.3 0.85 9.8 3.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Phage_holin_3_6 PF07332.11 KER30595.1 - 8.6 6.4 18.8 1.1 9.3 5.5 2.8 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Syntaxin PF00804.25 KER30596.1 - 1e-43 149.3 9.5 1e-43 149.3 9.5 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KER30596.1 - 5.9e-19 67.8 2.3 5.9e-19 67.8 2.3 1.9 2 0 0 2 2 1 1 SNARE domain Lzipper-MIP1 PF14389.6 KER30596.1 - 0.0095 16.2 1.0 0.018 15.3 1.0 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Syntaxin_2 PF14523.6 KER30596.1 - 0.05 14.0 5.1 0.26 11.7 0.1 2.8 2 1 0 2 2 2 0 Syntaxin-like protein DUF4258 PF14076.6 KER30596.1 - 0.076 13.4 0.1 0.35 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4258) T2SSF PF00482.23 KER30596.1 - 0.078 12.9 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF4658 PF15555.6 KER30596.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Arc_PepC_II PF06847.11 KER30596.1 - 0.25 11.9 1.5 3.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Lge1 PF11488.8 KER30596.1 - 1.2 9.4 4.1 0.62 10.3 1.0 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF1910 PF08928.10 KER30596.1 - 1.6 8.8 8.7 0.27 11.2 2.8 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1910) V-SNARE PF05008.15 KER30596.1 - 6.3 7.2 9.3 2.9 8.3 5.0 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FEZ PF07763.13 KER30597.1 - 8.2e-32 110.9 0.1 1.3e-31 110.2 0.1 1.4 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.9 KER30597.1 - 0.0069 16.0 0.9 0.012 15.2 0.2 1.6 2 0 0 2 2 2 1 Schwannomin-interacting protein 1 DUF5102 PF17104.5 KER30597.1 - 0.013 15.5 0.9 7.8 6.4 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5102) DUF2379 PF09543.10 KER30597.1 - 0.24 11.6 2.6 2.1 8.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) CBFD_NFYB_HMF PF00808.23 KER30598.1 - 4.7e-05 23.6 0.4 6.3e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M22 PF00814.25 KER30599.1 - 5.3e-45 154.2 0.0 1.2e-40 140.0 0.0 2.1 2 0 0 2 2 2 2 Glycoprotease family Laps PF10169.9 KER30601.1 - 5.3e-13 49.7 12.5 8.7e-13 49.0 12.5 1.4 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.9 KER30601.1 - 2.2e-06 27.8 8.1 2.2e-06 27.8 8.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) SRF-TF PF00319.18 KER30601.1 - 0.036 13.6 1.0 0.036 13.6 1.0 1.7 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) FG-GAP PF01839.23 KER30604.1 - 8.6e-21 73.7 20.6 3.9e-08 33.3 1.5 5.6 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.6 KER30604.1 - 4.8e-11 43.1 4.4 1.2e-06 29.0 1.5 3.6 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KER30604.1 - 3e-07 30.6 14.0 1.5 9.2 0.0 5.8 5 0 0 5 5 5 5 FG-GAP repeat Integrin_alpha2 PF08441.12 KER30604.1 - 3.3e-07 29.6 0.0 6.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Integrin alpha PsbJ PF01788.17 KER30604.1 - 3.3e-06 26.8 2.4 8.3e-06 25.6 2.4 1.6 1 0 0 1 1 1 1 PsbJ zf-GRF PF06839.12 KER30604.1 - 3.1 8.0 5.4 27 5.0 0.0 3.1 3 0 0 3 3 3 0 GRF zinc finger UreE_N PF02814.15 KER30607.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain AAA PF00004.29 KER30608.1 - 7.4e-54 181.7 0.0 6.8e-41 139.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PIG-L PF02585.17 KER30608.1 - 1.5e-21 77.4 0.0 3.1e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RuvB_N PF05496.12 KER30608.1 - 7.3e-07 29.1 0.0 0.0042 16.8 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KER30608.1 - 1.3e-06 28.9 0.6 0.014 15.8 0.1 3.7 2 2 1 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 KER30608.1 - 1.6e-06 28.1 0.0 0.0005 20.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_lid_3 PF17862.1 KER30608.1 - 2.5e-06 27.2 0.0 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KER30608.1 - 1.9e-05 24.7 0.1 0.0031 17.5 0.0 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KER30608.1 - 0.00015 21.8 0.0 0.046 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KER30608.1 - 0.00019 21.7 0.4 0.066 13.5 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KER30608.1 - 0.00026 21.5 0.1 0.016 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KER30608.1 - 0.00052 20.4 0.0 0.23 11.8 0.0 3.1 2 1 1 3 3 3 1 RNA helicase AAA_33 PF13671.6 KER30608.1 - 0.00057 20.1 0.0 0.062 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KER30608.1 - 0.00057 20.0 0.0 0.005 17.0 0.0 2.5 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KER30608.1 - 0.0023 17.4 1.6 0.075 12.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KER30608.1 - 0.0026 17.7 0.6 0.28 11.1 0.0 3.4 3 1 0 3 3 2 1 NACHT domain AAA_28 PF13521.6 KER30608.1 - 0.007 16.6 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KER30608.1 - 0.0094 15.8 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KER30608.1 - 0.012 15.6 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KER30608.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KER30608.1 - 0.024 14.4 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 KER30608.1 - 0.03 13.5 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 KER30608.1 - 0.033 14.0 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KER30608.1 - 0.059 12.9 0.7 14 5.2 0.1 3.2 2 1 1 3 3 3 0 AAA domain SRPRB PF09439.10 KER30608.1 - 0.15 11.5 0.0 20 4.5 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 KER30608.1 - 0.15 11.7 0.0 0.88 9.3 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KER30608.1 - 0.19 12.1 0.3 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 KER30610.1 - 6e-12 45.7 42.0 2.3e-07 31.0 10.9 3.4 3 0 0 3 3 3 3 Ring finger domain PHD PF00628.29 KER30610.1 - 5.1e-11 42.3 5.8 5.1e-11 42.3 5.8 3.2 3 0 0 3 3 2 1 PHD-finger Zn_ribbon_17 PF17120.5 KER30610.1 - 2.2e-08 33.6 29.1 3.2e-06 26.7 6.3 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KER30610.1 - 1.5e-06 27.9 10.2 1.5e-06 27.9 10.2 3.8 3 1 1 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER30610.1 - 1.7e-06 27.8 36.3 3.5e-05 23.6 10.5 3.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER30610.1 - 6.9e-06 26.3 31.9 0.0029 17.8 9.7 3.8 3 1 0 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KER30610.1 - 1.3e-05 24.9 6.7 1.3e-05 24.9 6.7 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER30610.1 - 6.7e-05 22.8 11.2 6.7e-05 22.8 11.2 3.6 4 0 0 4 4 3 2 RING-type zinc-finger zf-RING_10 PF16685.5 KER30610.1 - 0.0013 18.8 5.5 0.0013 18.8 5.5 3.0 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KER30610.1 - 0.0019 18.3 9.8 0.0019 18.3 9.8 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KER30610.1 - 0.035 14.1 22.9 0.96 9.5 2.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KER30610.1 - 0.075 13.2 22.7 0.17 12.1 2.7 3.8 3 0 0 3 3 3 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KER30610.1 - 0.077 13.3 21.8 0.21 11.9 5.2 3.5 2 1 1 3 3 3 0 PHD-like zinc-binding domain zf-Nse PF11789.8 KER30610.1 - 0.25 11.2 14.3 0.18 11.7 3.7 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 KER30610.1 - 0.29 11.3 23.0 0.074 13.2 1.3 3.4 3 0 0 3 3 2 0 KIAA1045 RING finger Reticulon PF02453.17 KER30613.1 - 1.1e-37 129.5 4.0 1.7e-37 128.8 4.0 1.3 1 0 0 1 1 1 1 Reticulon RVT_1 PF00078.27 KER30613.1 - 0.044 13.3 0.1 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HATPase_c PF02518.26 KER30615.1 - 1.2e-11 45.1 0.0 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KER30615.1 - 0.021 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glutaredoxin PF00462.24 KER30617.1 - 1.1e-20 73.6 0.0 2.8e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KER30617.1 - 1.6e-13 50.5 0.0 3.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KER30617.1 - 0.0032 17.4 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 KER30617.1 - 0.0032 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 KER30617.1 - 0.0072 16.8 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KER30617.1 - 0.01 16.1 0.3 0.15 12.4 0.1 2.4 1 1 1 2 2 2 0 Thioredoxin-like SH3BGR PF04908.15 KER30617.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein G-patch PF01585.23 KER30618.1 - 1.2e-12 47.5 1.1 2.6e-12 46.4 1.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KER30618.1 - 1.2e-06 28.2 0.1 2.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER30618.1 - 0.016 15.0 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif G-patch_2 PF12656.7 KER30618.1 - 0.018 15.2 0.4 0.047 13.8 0.4 1.7 1 0 0 1 1 1 0 G-patch domain Lipase_bact_N PF12262.8 KER30618.1 - 0.057 12.8 0.1 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal DHHC PF01529.20 KER30619.1 - 3.9e-06 27.0 7.1 3.9e-06 27.0 7.1 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase MIP-T3_C PF17749.1 KER30620.1 - 3e-36 124.7 3.2 3e-36 124.7 3.2 2.9 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 KER30620.1 - 2.4e-16 59.7 0.0 6.2e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain Spc7 PF08317.11 KER30620.1 - 0.002 17.1 5.5 0.002 17.1 5.5 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Fib_alpha PF08702.10 KER30620.1 - 0.0056 16.9 1.9 0.019 15.2 1.9 1.9 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family BRICHOS PF04089.14 KER30620.1 - 0.055 13.7 0.3 3.2 8.1 0.0 2.8 2 0 0 2 2 2 0 BRICHOS domain SOG2 PF10428.9 KER30620.1 - 1.1 8.3 16.0 0.12 11.5 11.1 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Septin PF00735.18 KER30621.1 - 1.2e-104 349.6 0.0 2.2e-104 348.7 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KER30621.1 - 1.9e-08 34.3 0.0 5e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KER30621.1 - 0.00018 20.9 0.0 0.00049 19.5 0.0 1.7 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KER30621.1 - 0.00028 20.8 3.9 0.0012 18.7 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KER30621.1 - 0.0059 16.0 0.5 0.012 15.0 0.0 1.7 2 0 0 2 2 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KER30621.1 - 0.0074 15.8 1.3 6.2 6.3 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KER30621.1 - 0.011 16.1 0.2 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KER30621.1 - 0.013 15.8 0.1 0.052 13.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain Spore_GerAC PF05504.11 KER30621.1 - 0.019 15.2 4.7 0.044 14.0 4.7 1.6 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal ABC_tran PF00005.27 KER30621.1 - 0.019 15.5 0.6 0.55 10.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 KER30621.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.22 KER30621.1 - 0.027 14.1 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.23 KER30621.1 - 0.028 14.5 7.2 0.47 10.5 0.3 3.3 2 1 1 3 3 3 0 Dynamin family DUF1719 PF08224.11 KER30621.1 - 0.029 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) IIGP PF05049.13 KER30621.1 - 0.032 13.3 2.4 0.039 13.0 0.1 2.2 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 KER30621.1 - 0.069 12.7 0.0 0.069 12.7 0.0 1.9 3 0 0 3 3 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KER30621.1 - 0.077 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KER30621.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KER30621.1 - 0.15 11.8 2.3 0.48 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Fez1 PF06818.15 KER30621.1 - 0.16 12.4 13.6 0.31 11.5 13.6 1.4 1 0 0 1 1 1 0 Fez1 Coiled-coil_56 PF09813.9 KER30621.1 - 1.1 9.4 5.8 5.2 7.2 4.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 AAA_23 PF13476.6 KER30621.1 - 1.2 9.6 8.2 20 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain HAUS6_N PF14661.6 KER30621.1 - 1.3 8.5 8.9 2.4 7.7 8.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fimbrial_PilY2 PF14481.6 KER30623.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Methyltransf_16 PF10294.9 KER30624.1 - 1.5e-10 41.1 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KER30624.1 - 0.00086 19.1 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Gpi16 PF04113.14 KER30625.1 - 2.1e-121 406.1 0.0 8.4e-120 400.8 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pkinase PF00069.25 KER30626.1 - 1.2e-54 185.4 0.0 2e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30626.1 - 4.9e-39 134.2 0.0 7.8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER30626.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IZUMO PF15005.6 KER30626.1 - 0.046 14.2 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated SH2 PF00017.24 KER30627.1 - 2e-10 40.6 0.0 8.3e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 SH2 domain zf-RING_9 PF13901.6 KER30628.1 - 8.9e-56 189.1 13.3 1.6e-55 188.3 13.3 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon FLYWCH PF04500.16 KER30629.1 - 5.3e-11 42.5 0.3 1.1e-09 38.3 0.2 2.4 2 0 0 2 2 2 1 FLYWCH zinc finger domain TMEM247 PF15444.6 KER30629.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 247 NPR3 PF03666.13 KER30630.1 - 1.9e-19 69.8 9.6 4.2e-17 62.1 3.8 4.0 4 1 0 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 Alba PF01918.21 KER30631.1 - 5.4e-06 26.1 0.0 0.011 15.5 0.0 2.2 1 1 1 2 2 2 2 Alba HMG_box PF00505.19 KER30632.1 - 4.1e-17 62.3 2.7 1.4e-16 60.6 2.7 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER30632.1 - 8.1e-06 26.3 1.1 8.1e-06 26.3 1.1 2.5 2 0 0 2 2 2 1 HMG-box domain Spore_III_AF PF09581.10 KER30632.1 - 0.038 14.0 5.6 0.11 12.6 5.6 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Bud13 PF09736.9 KER30632.1 - 9.1 6.7 34.6 8.8 6.7 19.1 2.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex START PF01852.19 KER30633.1 - 0.00027 20.4 0.2 0.35 10.2 0.0 2.1 2 0 0 2 2 2 2 START domain SLC3A2_N PF16028.5 KER30633.1 - 0.012 15.2 0.2 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Pneumo_M2 PF07380.11 KER30633.1 - 0.032 14.5 0.6 8.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Pneumovirus M2 protein BC10 PF06726.12 KER30633.1 - 0.036 14.3 1.8 6.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 DUF2967 PF11179.8 KER30633.1 - 0.053 11.6 0.1 3.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Alpha-amyl_C PF09071.10 KER30633.1 - 0.054 13.4 1.2 10 6.1 0.1 2.3 2 0 0 2 2 2 0 Alpha-amylase, C terminal zf-CDGSH PF09360.10 KER30633.1 - 0.54 10.5 7.3 3.9 7.8 0.4 2.5 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type RVT_1 PF00078.27 KER30634.1 - 5.5e-19 68.6 0.0 6.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Astro_capsid_p PF12226.8 KER30634.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SR-25 PF10500.9 KER30635.1 - 0.41 10.2 3.5 0.6 9.7 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNF PF00209.18 KER30637.1 - 1.7e-64 218.4 20.1 1.3e-51 175.9 10.1 2.1 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Exo_endo_phos_2 PF14529.6 KER30637.1 - 2e-08 34.1 0.1 5.2e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER30637.1 - 0.0048 16.4 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 KER30639.1 - 3.6e-05 23.4 0.0 0.00015 21.4 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TSSC4 PF15264.6 KER30639.1 - 0.034 14.4 0.0 18 5.6 0.0 2.9 3 0 0 3 3 3 0 Tumour suppressing sub-chromosomal transferable candidate 4 Rep_4 PF05797.11 KER30639.1 - 0.22 10.6 2.0 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) A_deaminase PF00962.22 KER30640.1 - 6.7e-25 88.1 0.0 1.1e-24 87.4 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Strabismus PF06638.11 KER30641.1 - 8.4e-111 371.1 0.1 7.7e-96 321.7 0.5 3.8 2 1 0 2 2 2 2 Strabismus protein RhoGEF PF00621.20 KER30642.1 - 1.5e-27 97.0 1.2 2.6e-27 96.3 1.2 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KER30642.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER30642.1 - 2.3e-09 36.7 0.0 4.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KER30642.1 - 2.5e-06 27.1 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KER30642.1 - 0.044 14.3 0.1 0.13 12.8 0.1 1.9 1 1 0 1 1 1 0 PH domain Ras PF00071.22 KER30651.1 - 5.6e-49 165.9 0.0 6.5e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER30651.1 - 3.4e-17 62.8 0.0 5.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER30651.1 - 3.3e-06 26.7 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER30651.1 - 0.0002 21.3 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KER30651.1 - 0.0094 15.5 0.2 0.12 11.9 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER30651.1 - 0.032 14.3 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KER30651.1 - 0.051 13.0 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 KER30651.1 - 0.067 12.9 0.2 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KER30652.1 - 2.2e-13 50.3 0.0 3.6e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER30652.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KER30652.1 - 0.0027 17.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Seryl_tRNA_N PF02403.22 KER30652.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Enterotoxin_b PF01376.18 KER30652.1 - 0.091 13.0 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DUF1317 PF07026.11 KER30653.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1317) TRP_2 PF08344.11 KER30654.1 - 9.4e-27 93.0 1.6 4.3e-26 90.9 0.5 2.6 2 0 0 2 2 2 1 Transient receptor ion channel II Ank_2 PF12796.7 KER30654.1 - 8.9e-10 39.0 0.1 1.9e-06 28.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER30654.1 - 1.2e-07 31.5 0.5 0.067 13.8 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KER30654.1 - 8.7e-07 29.4 0.0 0.00082 19.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KER30654.1 - 0.012 16.0 0.0 31 5.2 0.0 4.2 3 1 0 3 3 3 0 Ankyrin repeat Ion_trans PF00520.31 KER30655.1 - 2.4e-12 46.6 2.6 3.4e-12 46.1 2.0 1.5 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 KER30655.1 - 0.012 14.3 1.9 0.018 13.8 1.9 1.3 1 0 0 1 1 1 0 Polycystin cation channel BTB PF00651.31 KER30656.1 - 2.7e-16 59.8 0.0 5.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain JmjC PF02373.22 KER30657.1 - 6.9e-16 58.7 3.1 7.6e-15 55.3 3.1 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KER30657.1 - 6.2e-13 49.0 0.1 2.3e-12 47.2 0.1 1.9 1 1 0 1 1 1 1 Cupin-like domain Aldolase_II PF00596.21 KER30658.1 - 5.4e-31 108.0 0.0 1.2e-30 106.9 0.0 1.6 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EF1_GNE PF00736.19 KER30658.1 - 1.5e-21 76.4 0.0 2.6e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KER30658.1 - 2.1e-06 28.0 1.1 2.1e-06 28.0 1.1 3.9 5 0 0 5 5 5 1 Eukaryotic elongation factor 1 beta central acidic region DUF3619 PF12279.8 KER30658.1 - 0.26 11.6 1.7 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Complex1_LYR_2 PF13233.6 KER30659.1 - 2e-12 47.7 0.0 4.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KER30659.1 - 2.5e-06 27.4 0.3 2.5e-06 27.4 0.3 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF3134 PF11332.8 KER30660.1 - 0.0032 17.8 0.0 0.63 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3134) Prot_ATP_OB_N PF17758.1 KER30660.1 - 0.017 14.7 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain zf-Di19 PF05605.12 KER30661.1 - 9.9e-12 45.0 3.0 9.9e-12 45.0 3.0 3.3 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 KER30661.1 - 3e-11 42.9 8.1 3e-11 42.9 8.1 2.2 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-RING_2 PF13639.6 KER30661.1 - 3.8 7.9 14.0 25 5.3 0.1 3.8 2 1 0 3 3 3 0 Ring finger domain Pkinase PF00069.25 KER30662.1 - 1.6e-11 44.1 0.0 5.2e-09 35.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER30662.1 - 7.2e-05 22.2 0.0 0.013 14.8 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KER30662.1 - 0.036 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KER30663.1 - 1.6e-10 40.8 0.0 2.1e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30663.1 - 7.5e-05 22.1 0.0 0.0076 15.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KER30663.1 - 0.032 14.2 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KER30663.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Claudin_2 PF13903.6 KER30664.1 - 1.1e-08 35.1 9.4 1.5e-08 34.6 9.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Geminin PF07412.12 KER30665.1 - 1.4e-10 41.3 1.6 1.9e-10 40.8 1.3 1.4 1 1 0 1 1 1 1 Geminin Cnn_1N PF07989.11 KER30665.1 - 0.018 15.2 1.4 0.018 15.2 1.4 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BLI1 PF17324.2 KER30665.1 - 0.019 15.6 0.8 0.033 14.8 0.8 1.3 1 0 0 1 1 1 0 BLOC-1 interactor 1 GLE1 PF07817.13 KER30665.1 - 0.056 12.6 0.2 0.08 12.1 0.2 1.2 1 0 0 1 1 1 0 GLE1-like protein Cir_Bir_Yir PF06022.11 KER30665.1 - 0.074 12.5 0.4 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir RSB_motif PF16294.5 KER30668.1 - 0.025 14.8 3.2 0.025 14.8 3.2 2.8 3 1 0 3 3 3 0 RNSP1-SAP18 binding (RSB) motif Glyco_transf_7N PF13733.6 KER30670.1 - 1.4e-38 131.5 0.1 2.2e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 KER30670.1 - 2.5e-22 78.3 0.2 4.9e-22 77.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Nudc_N PF14050.6 KER30670.1 - 0.14 12.2 0.2 0.28 11.2 0.2 1.5 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Gal_Lectin PF02140.18 KER30673.1 - 3.8 8.0 21.2 0.42 11.1 0.8 3.9 4 0 0 4 4 4 0 Galactose binding lectin domain ABC1 PF03109.16 KER30676.1 - 5.7e-24 84.6 0.0 1.2e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Kelch_4 PF13418.6 KER30680.1 - 6.2e-10 38.9 12.7 8.2e-06 25.7 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KER30680.1 - 7.9e-10 38.8 9.0 1.2e-05 25.5 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KER30680.1 - 4.9e-07 29.6 1.2 0.056 13.4 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 KER30680.1 - 6e-07 29.5 0.4 0.00014 22.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KER30680.1 - 0.0014 18.2 0.3 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 KER30680.1 - 0.0099 15.8 9.0 0.011 15.7 0.0 3.8 4 0 0 4 4 4 1 Kelch motif zf-CCCH_2 PF14608.6 KER30680.1 - 0.055 14.0 6.3 0.067 13.7 0.3 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger ESPR PF13018.6 KER30680.1 - 0.15 11.9 0.3 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system PNP_UDP_1 PF01048.20 KER30681.1 - 2.7e-35 121.7 0.0 3.2e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MOR2-PAG1_N PF14222.6 KER30684.1 - 9.2e-62 209.7 11.1 7.2e-36 124.3 1.4 3.7 2 1 1 4 4 4 3 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KER30684.1 - 8.7e-29 101.1 0.3 1.2e-26 94.2 0.0 3.6 3 1 0 3 3 3 1 Cell morphogenesis C-terminal HEAT_2 PF13646.6 KER30684.1 - 0.0009 19.6 1.2 0.0069 16.8 0.3 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KER30684.1 - 0.0068 16.9 0.1 0.3 11.6 0.0 3.5 2 0 0 2 2 2 1 HEAT-like repeat Apolipoprotein PF01442.18 KER30684.1 - 0.35 10.7 2.7 3.8 7.3 0.6 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain MOR2-PAG1_mid PF14228.6 KER30684.1 - 3.2 5.2 9.0 15 3.1 0.2 4.4 5 0 0 5 5 5 0 Cell morphogenesis central region WD40 PF00400.32 KER30686.1 - 8.4e-25 86.6 14.4 2.4e-06 28.1 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER30686.1 - 0.00011 22.4 1.5 0.13 12.5 0.0 4.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CAF1C_H4-bd PF12265.8 KER30686.1 - 0.00023 21.4 0.3 0.0015 18.8 0.0 2.6 4 0 0 4 4 4 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 KER30686.1 - 0.004 17.1 0.5 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Jun PF03957.13 KER30687.1 - 4.5e-09 36.5 1.7 2.3e-08 34.2 0.1 2.8 2 1 0 2 2 2 1 Jun-like transcription factor bZIP_1 PF00170.21 KER30687.1 - 1e-07 31.9 11.7 1.8e-07 31.1 11.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KER30687.1 - 2.3e-07 31.2 4.6 2.3e-07 31.2 4.6 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KER30687.1 - 0.00033 20.7 12.5 0.00067 19.7 12.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper SlyX PF04102.12 KER30687.1 - 0.026 15.1 0.2 0.072 13.7 0.2 1.7 1 0 0 1 1 1 0 SlyX CCD48 PF15799.5 KER30687.1 - 0.062 11.6 2.1 0.094 11.0 2.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 GAS PF13851.6 KER30687.1 - 0.095 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 KER30687.1 - 0.19 11.6 0.3 0.34 10.8 0.3 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 KER30688.1 - 1.3e-86 285.2 21.5 2.6e-15 56.8 0.7 12.2 9 4 3 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER30688.1 - 6.2e-71 233.9 35.0 2.3e-12 47.2 0.0 15.4 9 5 7 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 KER30688.1 - 4.5e-68 222.9 62.4 2.8e-08 33.8 0.1 19.6 19 0 0 19 19 19 17 Ankyrin repeat Ank_5 PF13857.6 KER30688.1 - 3.7e-64 211.9 45.7 2e-07 31.2 0.2 16.8 13 4 3 17 17 17 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER30688.1 - 4.6e-58 186.3 46.6 2.9e-05 24.1 0.1 19.8 20 0 0 20 20 20 15 Ankyrin repeat GATase_7 PF13537.6 KER30688.1 - 0.0021 18.0 0.0 0.97 9.4 0.0 3.8 4 0 0 4 4 4 1 Glutamine amidotransferase domain DUF2520 PF10728.9 KER30688.1 - 0.5 10.1 13.9 0.2 11.5 0.3 5.3 6 1 1 7 7 7 0 Domain of unknown function (DUF2520) ADIP PF11559.8 KER30689.1 - 7.6e-14 52.1 12.8 7.6e-14 52.1 12.8 3.0 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding ERM PF00769.19 KER30689.1 - 0.0059 16.5 11.8 0.0059 16.5 11.8 2.7 2 1 1 3 3 3 1 Ezrin/radixin/moesin family Spc7 PF08317.11 KER30689.1 - 0.091 11.6 16.0 0.055 12.4 8.0 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein Sec34 PF04136.15 KER30689.1 - 0.52 10.2 9.4 1.4 8.8 0.2 2.5 2 0 0 2 2 2 0 Sec34-like family His_Phos_1 PF00300.22 KER30690.1 - 1.4e-32 113.0 0.0 4.4e-27 95.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DHFR_1 PF00186.19 KER30691.1 - 2e-27 95.9 0.0 2.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase NAD_binding_2 PF03446.15 KER30694.1 - 1.9e-44 151.6 0.0 2.7e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KER30694.1 - 4.9e-36 123.6 0.0 7.8e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 KER30694.1 - 4.1e-07 30.1 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KER30694.1 - 2.9e-06 26.8 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KER30694.1 - 4e-05 24.1 0.0 0.00017 22.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KER30694.1 - 0.0079 16.6 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 KER30694.1 - 0.0094 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KER30694.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KER30694.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 KER30694.1 - 0.08 13.8 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 KER30694.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KER30694.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KER30694.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-H2C2_2 PF13465.6 KER30695.1 - 3.5e-13 49.3 8.9 2.9e-08 33.7 2.6 4.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER30695.1 - 8.6e-11 41.7 33.4 5.8e-06 26.5 0.6 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER30695.1 - 1.6e-06 28.4 28.8 0.0033 18.1 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER30695.1 - 0.014 15.6 4.4 6.6 7.2 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER30695.1 - 0.018 15.4 4.9 13 6.3 0.7 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KER30695.1 - 0.022 14.9 1.3 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger TcdB_toxin_midC PF12255.8 KER30695.1 - 0.032 14.3 4.2 2.8 8.0 1.1 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/C-terminal region Zn-C2H2_12 PF18112.1 KER30695.1 - 0.039 14.4 3.3 2.3 8.8 1.0 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 KER30695.1 - 0.51 10.4 18.2 0.39 10.8 3.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER30695.1 - 6.1 7.2 13.5 0.13 12.6 3.9 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TTL PF03133.15 KER30696.1 - 5.4e-68 229.3 0.1 1.2e-67 228.2 0.1 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER30696.1 - 0.0019 17.5 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp BRCT_assoc PF12820.7 KER30696.1 - 1.4 8.7 5.8 0.2 11.5 0.4 2.4 3 0 0 3 3 3 0 Serine-rich domain associated with BRCT SIL1 PF16782.5 KER30697.1 - 0.00011 21.5 0.1 0.0088 15.3 0.0 2.1 1 1 1 2 2 2 2 Nucleotide exchange factor SIL1 CALCOCO1 PF07888.11 KER30697.1 - 0.012 14.5 0.1 0.036 13.0 0.1 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fes1 PF08609.10 KER30697.1 - 2 9.3 9.3 5.4 8.0 5.0 3.1 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 EF-hand_7 PF13499.6 KER30698.1 - 1.6e-18 66.9 4.9 4.8e-07 30.1 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KER30698.1 - 1.5e-14 52.4 8.6 1e-07 31.0 0.1 5.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KER30698.1 - 4.9e-14 51.0 6.7 4.7e-07 29.2 0.1 5.3 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 KER30698.1 - 9e-12 44.7 1.4 0.00032 20.5 0.0 6.1 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 KER30698.1 - 2.7e-11 42.4 3.5 0.00022 20.6 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 KER30698.1 - 0.0021 18.0 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER30698.1 - 0.15 12.4 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Misat_Tub_SegII PF10644.9 KER30699.1 - 5.4e-13 49.3 0.0 1.5e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KER30699.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KER30699.1 - 0.0024 18.1 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Erf4 PF10256.9 KER30700.1 - 4.7e-11 42.8 0.0 6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PH PF00169.29 KER30702.1 - 1.1e-07 32.3 0.1 2.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Ig_3 PF13927.6 KER30704.1 - 0.0067 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER30704.1 - 0.097 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 KER30704.1 - 0.098 13.0 0.0 1.6 9.2 0.0 2.3 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KER30704.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Immunoglobulin V-set domain Adeno_E3_CR2 PF02439.15 KER30704.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Chorein_N PF12624.7 KER30706.1 - 8.9e-28 96.7 1.2 4.6e-27 94.4 1.2 2.0 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF3963 PF13124.6 KER30706.1 - 8.1 6.5 6.1 8.2 6.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) VPS13_mid_rpt PF16910.5 KER30707.1 - 2.4e-77 259.5 8.3 1.2e-65 221.3 0.0 5.6 6 0 0 6 6 6 3 Repeating coiled region of VPS13 VPS13_C PF16909.5 KER30707.1 - 4.6e-62 208.9 4.8 3.8e-58 196.2 0.1 3.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KER30707.1 - 7.1e-33 114.1 0.0 2.4e-31 109.1 0.0 2.9 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KER30707.1 - 2.1e-32 112.9 5.1 1.5e-30 106.8 2.5 4.0 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 KER30707.1 - 2.6e-06 27.7 0.0 1.1e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain CCDC53 PF10152.9 KER30707.1 - 0.12 12.8 1.6 0.77 10.2 0.2 2.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CAP PF00188.26 KER30711.1 - 1e-32 113.6 1.3 5.6e-20 72.4 0.5 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Utp14 PF04615.13 KER30712.1 - 3.4e-84 283.9 45.1 1.6e-44 152.7 33.5 2.0 1 1 1 2 2 2 2 Utp14 protein MFS_1 PF07690.16 KER30713.1 - 1.5e-27 96.4 19.9 2e-25 89.5 7.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.23 KER30714.1 - 2.1e-73 246.1 0.0 9.4e-65 217.8 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 KER30714.1 - 1.9e-22 79.4 0.3 6.2e-22 77.8 0.3 1.8 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER30714.1 - 1e-20 73.9 1.1 2.4e-20 72.7 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KER30714.1 - 4.1e-07 29.6 0.1 9.4e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KER30714.1 - 4.3e-05 23.5 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KER30714.1 - 0.0038 17.1 0.0 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER30714.1 - 0.029 14.8 0.6 0.11 12.9 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KER30714.1 - 0.057 13.7 0.0 0.26 11.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KER30714.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RuvB_N PF05496.12 KER30714.1 - 0.17 11.6 0.0 0.53 10.0 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Lig_chan PF00060.26 KER30716.1 - 1.6e-12 47.5 0.6 2.5e-12 46.9 0.6 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Y_phosphatase PF00102.27 KER30717.1 - 7.2e-110 366.1 0.1 2.2e-77 259.8 1.1 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KER30717.1 - 8.4e-23 80.5 0.3 2e-06 28.1 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Ig_3 PF13927.6 KER30717.1 - 2.6e-05 24.7 0.3 0.00011 22.7 0.3 2.2 1 0 0 1 1 1 1 Immunoglobulin domain DSPc PF00782.20 KER30717.1 - 0.00011 22.1 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ig PF00047.25 KER30717.1 - 0.0013 18.9 0.3 0.0036 17.4 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin domain PTPlike_phytase PF14566.6 KER30717.1 - 0.029 14.5 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate I-set PF07679.16 KER30717.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Y_phosphatase3 PF13350.6 KER30717.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Ig_2 PF13895.6 KER30717.1 - 0.13 12.6 0.2 0.53 10.6 0.2 2.1 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 KER30717.1 - 0.14 12.3 0.2 0.66 10.2 0.2 2.2 1 1 1 2 2 2 0 Immunoglobulin V-set domain CH PF00307.31 KER30718.1 - 5.1e-51 171.4 1.3 7e-29 100.2 0.0 3.8 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 KER30718.1 - 5.9e-44 148.8 21.6 6.8e-16 58.7 1.3 4.6 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 KER30718.1 - 1.6e-22 79.3 0.0 5.2e-22 77.7 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KER30718.1 - 8.6e-10 38.3 0.0 1.4e-07 31.2 0.1 2.8 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.32 KER30718.1 - 4.5e-07 28.9 0.6 0.00022 20.5 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KER30718.1 - 6.8e-05 22.5 0.1 0.74 9.9 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER30718.1 - 0.00023 21.5 0.0 0.0014 19.0 0.0 2.5 1 1 0 1 1 1 1 EF-hand domain pair CH_2 PF06294.11 KER30718.1 - 0.0064 16.6 0.2 13 6.0 0.0 3.9 3 0 0 3 3 3 2 CH-like domain in sperm protein Wtap PF17098.5 KER30718.1 - 0.029 14.3 5.9 0.93 9.4 0.5 3.3 2 1 1 3 3 3 0 WTAP/Mum2p family SlyX PF04102.12 KER30718.1 - 4.5 8.0 8.6 16 6.2 0.9 4.0 2 0 0 2 2 2 0 SlyX AcetylCoA_hyd_C PF13336.6 KER30722.1 - 8.8e-50 168.6 0.0 1.9e-49 167.5 0.0 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KER30722.1 - 8.8e-17 61.7 0.0 1.5e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KER30723.1 - 2.9e-57 192.9 0.0 4.5e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KER30723.1 - 1.2e-15 58.1 0.0 2.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DUF5476 PF17570.2 KER30724.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5476) DUF3512 PF12024.8 KER30725.1 - 3.4e-14 52.9 0.0 6.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Bromodomain PF00439.25 KER30725.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Laminin_G_2 PF02210.24 KER30727.1 - 2.1e-57 193.1 0.3 6.7e-16 59.0 0.0 5.7 5 1 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 KER30727.1 - 5.3e-44 149.6 0.2 7.5e-14 52.1 0.0 6.1 6 0 0 6 6 6 5 Laminin G domain Syndecan PF01034.20 KER30727.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Laminin_G_3 PF13385.6 KER30727.1 - 0.0059 16.8 0.1 0.067 13.3 0.0 2.7 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 KER30727.1 - 0.032 14.5 20.1 0.062 13.6 8.7 2.7 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 KER30727.1 - 0.73 10.6 16.4 0.54 11.0 5.7 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF DUF4790 PF16037.5 KER30728.1 - 0.034 14.6 0.1 0.077 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) Phage_head_chap PF11113.8 KER30728.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Head assembly gene product MFS_1 PF07690.16 KER30729.1 - 1.1e-21 77.1 44.5 3.9e-11 42.5 17.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KER30729.1 - 0.0068 15.3 28.0 0.0089 14.9 2.4 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Prion_bPrPp PF11587.8 KER30729.1 - 5.3 7.0 5.7 38 4.2 0.3 3.2 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal Metallophos PF00149.28 KER30730.1 - 1.9e-18 67.7 0.0 3.1e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PFK PF00365.20 KER30731.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphofructokinase SelP_C PF04593.14 KER30731.1 - 0.011 15.8 0.4 1.2 9.1 0.0 2.5 2 1 1 3 3 3 0 Selenoprotein P, C terminal region Metallophos PF00149.28 KER30732.1 - 3.3e-20 73.4 0.0 4.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER30732.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain MFS_1 PF07690.16 KER30733.1 - 4.5e-22 78.5 35.4 1.3e-17 63.8 11.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-Sec23_Sec24 PF04810.15 KER30733.1 - 0.22 11.6 0.6 0.46 10.6 0.6 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glyco_transf_22 PF03901.17 KER30734.1 - 1.3e-39 136.7 26.6 2e-39 136.0 26.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SIR2 PF02146.17 KER30734.1 - 7.7e-19 68.3 0.0 5.5e-10 39.4 0.0 3.4 1 1 1 2 2 2 2 Sir2 family zf-H2C2_5 PF13909.6 KER30734.1 - 0.0041 16.8 1.1 0.01 15.5 1.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 KER30734.1 - 0.036 13.7 2.6 0.5 10.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2231 PF09990.9 KER30734.1 - 0.28 11.6 1.3 0.79 10.2 1.3 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) VASt PF16016.5 KER30735.1 - 5.4e-29 101.6 0.0 1.5e-28 100.2 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KER30735.1 - 2.1e-18 66.3 0.4 4.3e-18 65.3 0.4 1.5 1 0 0 1 1 1 1 GRAM domain MFS_1 PF07690.16 KER30738.1 - 9.7e-14 51.0 24.6 1.7e-13 50.2 24.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily IncD PF17628.2 KER30738.1 - 3.2 7.5 10.1 9.3 6.0 3.4 3.3 3 0 0 3 3 3 0 Inclusion membrane protein D FA_desaturase PF00487.24 KER30739.1 - 0.26 11.1 3.4 0.21 11.4 2.4 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DUF3301 PF11743.8 KER30740.1 - 0.0066 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) DDE_5 PF13546.6 KER30740.1 - 0.068 12.5 0.1 0.087 12.2 0.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Fer4_NifH PF00142.18 KER30740.1 - 0.095 12.1 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family zf-RING_2 PF13639.6 KER30741.1 - 2.7e-13 50.0 6.3 2.7e-13 50.0 6.3 2.8 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 KER30741.1 - 5.8e-10 39.3 6.3 5.8e-10 39.3 6.3 2.5 3 0 0 3 3 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KER30741.1 - 2e-08 33.9 6.3 2e-08 33.9 6.3 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER30741.1 - 5.2e-08 32.6 5.3 5.2e-08 32.6 5.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KER30741.1 - 1.6e-07 31.0 1.6 1.6e-07 31.0 1.6 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KER30741.1 - 1.7e-05 24.6 3.7 5.6e-05 22.9 3.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER30741.1 - 9.1e-05 22.4 1.9 0.00028 20.9 1.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KER30741.1 - 9.9e-05 22.2 4.1 9.9e-05 22.2 4.1 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER30741.1 - 0.00025 21.0 1.6 0.00025 21.0 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 KER30741.1 - 0.017 15.2 6.5 0.044 13.9 6.5 1.7 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KER30741.1 - 0.07 12.8 3.5 0.18 11.5 3.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KER30741.1 - 0.11 12.4 2.3 0.33 10.8 2.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KER30741.1 - 0.17 12.1 3.3 0.41 10.9 3.3 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KER30741.1 - 1.9 8.4 9.8 0.31 11.0 5.3 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KER30741.1 - 3.4 7.5 6.0 7.8 6.4 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dynein_light PF01221.18 KER30743.1 - 2.8e-08 34.0 0.0 5.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 KER30743.1 - 2.8e-07 30.9 0.6 7.7e-07 29.5 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER30743.1 - 3e-07 29.8 0.2 0.0091 15.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER30743.1 - 1.1e-05 24.7 0.1 0.019 14.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 KER30743.1 - 1.3e-05 24.5 0.5 0.0008 18.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KER30743.1 - 0.026 14.3 0.2 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair AbiEi_4 PF13338.6 KER30743.1 - 0.11 12.6 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Phytochelatin PF05023.14 KER30744.1 - 0.039 13.2 0.7 0.046 12.9 0.7 1.1 1 0 0 1 1 1 0 Phytochelatin synthase Fimbrial PF00419.20 KER30744.1 - 0.051 13.8 0.1 0.074 13.3 0.1 1.4 1 1 0 1 1 1 0 Fimbrial protein KAP_NTPase PF07693.14 KER30744.1 - 0.055 12.7 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain SAM_1 PF00536.30 KER30747.1 - 3.3e-05 24.2 0.0 6.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YbgS PF13985.6 KER30747.1 - 1.8 8.9 5.4 0.51 10.6 1.1 2.1 2 0 0 2 2 2 0 YbgS-like protein Ribosomal_S7e PF01251.18 KER30749.1 - 1e-72 243.8 0.6 1.2e-72 243.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4821 PF16092.5 KER30750.1 - 3.3e-71 240.0 0.0 1.4e-65 221.5 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) IMS PF00817.20 KER30751.1 - 3.4e-31 108.3 0.0 6.4e-20 71.7 0.0 3.2 3 0 0 3 3 3 2 impB/mucB/samB family IMS_C PF11799.8 KER30751.1 - 1.3e-14 54.9 0.6 5.6e-14 52.8 0.6 2.1 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KER30751.1 - 1.7e-07 31.1 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 KER30751.1 - 0.007 16.8 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Barrier to autointegration factor RNF220 PF15926.5 KER30751.1 - 0.025 14.2 1.8 0.041 13.5 0.1 2.1 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 PPTA PF01239.22 KER30753.1 - 1.9e-41 138.7 18.7 2e-12 46.4 0.9 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat LRR_9 PF14580.6 KER30753.1 - 8.3e-06 25.4 0.4 1.9e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KER30753.1 - 1.2e-05 25.6 12.3 0.0086 16.5 0.8 4.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER30753.1 - 2e-05 24.2 4.5 0.00023 20.9 1.2 3.6 2 1 2 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 KER30753.1 - 0.3 11.8 1.8 55 4.9 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat TPR_17 PF13431.6 KER30753.1 - 0.48 10.9 3.9 11 6.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_8 PF13855.6 KER30755.1 - 1.8e-17 62.9 29.4 1.7e-09 37.3 1.7 3.8 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KER30755.1 - 1.4e-12 47.6 18.8 3.4e-05 24.1 3.9 4.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) zf-C3HC4_3 PF13920.6 KER30755.1 - 2e-08 34.0 21.8 3.2e-08 33.3 21.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 KER30755.1 - 9.3e-07 28.9 0.0 0.00014 21.8 0.0 3.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KER30755.1 - 0.00092 19.6 0.0 0.0031 17.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 KER30755.1 - 0.055 14.0 15.9 0.93 10.3 0.6 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KER30755.1 - 0.23 11.6 8.8 4.4 7.6 0.5 4.1 4 0 0 4 4 4 0 Leucine Rich repeat FliP PF00813.20 KER30755.1 - 3.2 7.6 5.8 0.53 10.1 0.2 2.2 2 1 0 2 2 2 0 FliP family Ribosomal_L27A PF00828.19 KER30756.1 - 8.4e-12 45.9 0.0 1.3e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DS PF01916.17 KER30758.1 - 4.5e-119 397.0 0.0 5.8e-119 396.6 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase MRP-S35 PF10246.9 KER30758.1 - 5.8e-31 106.6 0.0 1e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 Synaptobrevin PF00957.21 KER30759.1 - 1.4e-11 44.0 0.1 2.5e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KER30759.1 - 2.6e-10 40.2 0.0 5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DNase-RNase PF02577.14 KER30760.1 - 0.094 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Bifunctional nuclease ENT PF03735.14 KER30762.1 - 9.5e-25 86.5 0.1 2.2e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 ENT domain Neur_chan_LBD PF02931.23 KER30763.1 - 3.2e-45 154.2 1.4 6.9e-45 153.1 1.4 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER30763.1 - 1.9e-27 96.9 7.6 4e-27 95.8 7.6 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ODV-E18 PF10717.9 KER30763.1 - 1.2 9.1 11.8 2.5 8.0 0.6 3.5 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 PAP_central PF04928.17 KER30764.1 - 1.7e-86 289.2 0.0 8.3e-85 283.7 0.0 2.1 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KER30764.1 - 3.8e-19 69.0 2.4 3.8e-12 46.2 0.2 2.8 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KER30764.1 - 4.4e-07 30.1 0.0 1.4e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Bombinin PF05298.11 KER30764.1 - 0.021 14.5 0.1 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Bombinin FAM83 PF07894.12 KER30764.1 - 0.097 12.2 0.8 6.1 6.3 0.1 2.3 2 0 0 2 2 2 0 FAM83 A-H Comm PF15957.5 KER30765.1 - 0.092 13.1 2.4 0.21 12.0 0.6 2.4 2 1 0 2 2 2 0 Commissureless Ldl_recept_a PF00057.18 KER30765.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A dsrm PF00035.26 KER30766.1 - 6.3e-12 46.0 0.0 2.4e-09 37.7 0.0 2.7 3 0 0 3 3 3 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KER30766.1 - 0.27 11.5 1.2 48 4.3 0.4 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ion_trans PF00520.31 KER30768.1 - 6.7e-30 104.1 15.7 9.8e-30 103.6 15.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER30768.1 - 5.3e-11 42.3 0.2 5.3e-11 42.3 0.2 2.3 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 KER30768.1 - 5.2e-08 32.8 0.0 9.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_9 PF13426.7 KER30768.1 - 0.00095 19.4 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain Apis_Csd PF11671.8 KER30769.1 - 0.034 14.2 3.9 0.067 13.2 3.9 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Pkinase PF00069.25 KER30770.1 - 1.2e-10 41.2 0.0 3.4e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain RVT_1 PF00078.27 KER30770.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EloA-BP1 PF15870.5 KER30770.1 - 0.032 14.5 1.4 0.052 13.8 0.0 2.0 3 0 0 3 3 3 0 ElonginA binding-protein 1 Pkinase PF00069.25 KER30771.1 - 2.8e-35 122.0 0.0 3.1e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30771.1 - 2.2e-13 50.1 0.0 2.3e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER30771.1 - 2.5e-06 27.0 0.0 2.6e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER30771.1 - 7.4e-06 25.5 0.0 8.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER30771.1 - 0.0025 16.6 0.0 0.0028 16.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KER30771.1 - 0.082 12.4 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 KER30771.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 KER30771.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KER30771.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Deltameth_res PF16020.5 KER30772.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Deltamethrin resistance Pkinase PF00069.25 KER30773.1 - 1.1e-38 133.1 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30773.1 - 1.1e-16 60.9 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER30773.1 - 1.3e-07 30.8 0.0 2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KER30773.1 - 0.00068 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER30773.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HLH PF00010.26 KER30774.1 - 5.3e-10 39.1 0.2 9.6e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HSD3 PF15244.6 KER30776.1 - 9.8e-17 61.6 7.2 7.2e-11 42.2 1.0 2.6 3 0 0 3 3 3 2 Spermatogenesis-associated protein 7, or HSD3 DUF3348 PF11828.8 KER30776.1 - 0.037 13.7 0.1 0.079 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) TPR_14 PF13428.6 KER30778.1 - 1.1e-13 50.7 19.9 0.14 13.0 0.1 8.6 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KER30778.1 - 7.6e-13 48.8 14.5 0.00011 22.6 0.2 5.9 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER30778.1 - 8.5e-13 47.4 19.0 0.002 18.1 0.1 10.5 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER30778.1 - 1.9e-11 43.2 9.6 0.00063 19.8 0.2 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER30778.1 - 3.8e-11 42.5 0.9 0.0017 18.0 0.1 6.2 7 1 1 8 8 7 2 TPR repeat TPR_17 PF13431.6 KER30778.1 - 1.3e-10 40.9 10.9 0.52 10.8 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER30778.1 - 6.7e-10 38.4 10.5 0.02 14.7 0.3 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER30778.1 - 2.3e-08 34.5 21.0 0.0026 18.3 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KER30778.1 - 5.2e-07 29.8 15.1 0.023 14.9 0.8 6.4 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KER30778.1 - 0.00012 22.3 22.0 0.034 14.4 0.3 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KER30778.1 - 0.00033 20.2 8.4 0.096 12.0 1.5 3.3 2 1 0 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 KER30778.1 - 0.00038 20.9 4.5 2.3 9.0 0.0 5.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPPII_N PF12583.8 KER30778.1 - 0.0012 19.4 0.1 0.0026 18.3 0.1 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal PknG_TPR PF16918.5 KER30778.1 - 0.016 14.0 0.7 0.03 13.1 0.1 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 KER30778.1 - 0.7 10.3 5.3 37 4.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RLL PF10036.9 KER30780.1 - 5.3e-30 105.1 0.0 5.7e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein His_Phos_2 PF00328.22 KER30781.1 - 0.033 13.5 0.0 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) UPF0020 PF01170.18 KER30782.1 - 9.5e-13 48.3 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KER30782.1 - 0.002 18.8 0.1 0.0098 16.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER30782.1 - 0.071 13.8 0.0 0.2 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KER30782.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 KER30782.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase PseudoU_synth_2 PF00849.22 KER30785.1 - 1.3e-08 35.1 0.0 3.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Not3 PF04065.15 KER30786.1 - 1.1e-79 267.1 26.8 1.5e-79 266.7 26.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KER30786.1 - 4.1e-33 114.2 8.2 4.1e-33 114.2 8.2 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4164 PF13747.6 KER30786.1 - 1.1 9.6 12.6 0.12 12.7 5.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Ysc84 PF04366.12 KER30787.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Las17-binding protein actin regulator HEPN_Swt1 PF18731.1 KER30788.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Swt1-like HEPN CDC50 PF03381.15 KER30789.1 - 6.6e-84 281.7 0.0 9.3e-84 281.2 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Use1 PF09753.9 KER30790.1 - 8.3e-67 225.5 1.0 1e-66 225.2 1.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCU PF04678.13 KER30790.1 - 0.029 14.5 1.6 0.063 13.4 1.6 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HAUS-augmin3 PF14932.6 KER30790.1 - 1.4 8.5 10.7 2.8 7.5 10.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 KER30790.1 - 7.5 6.6 10.7 17 5.4 10.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UFD1 PF03152.14 KER30791.1 - 1e-69 233.5 0.0 4.5e-69 231.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KER30791.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 ATHILA PF03078.15 KER30791.1 - 0.066 12.0 0.1 0.094 11.5 0.1 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family zf-C2H2_4 PF13894.6 KER30792.1 - 3.4e-14 52.3 58.0 0.0014 19.3 0.5 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 KER30792.1 - 2.4e-12 46.6 48.2 0.0023 18.3 0.8 8.8 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KER30792.1 - 0.00011 22.5 18.3 0.071 13.4 0.3 6.5 5 1 1 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KER30792.1 - 0.00011 22.5 6.0 0.0009 19.6 1.1 7.8 9 0 0 9 9 9 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER30792.1 - 0.00066 19.6 38.6 0.013 15.5 3.3 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 KER30792.1 - 0.0039 17.5 3.7 0.0039 17.5 3.7 7.6 7 1 0 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KER30792.1 - 0.032 14.2 0.5 0.032 14.2 0.5 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KER30792.1 - 0.042 14.1 0.0 0.042 14.1 0.0 8.4 9 1 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf_PR_Knuckle PF18445.1 KER30792.1 - 0.046 13.5 3.4 0.22 11.4 3.4 2.2 1 0 0 1 1 1 0 PR zinc knuckle motif zf-met PF12874.7 KER30792.1 - 1.4 9.4 27.6 0.81 10.2 2.1 6.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Pkinase PF00069.25 KER30794.1 - 5e-14 52.3 0.1 7.1e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30794.1 - 4.8e-08 32.6 0.1 6.4e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_2b PF00587.25 KER30796.1 - 1.5e-39 135.8 0.1 2.4e-39 135.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KER30796.1 - 5.9e-13 49.0 0.4 2e-12 47.3 0.4 1.9 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CRAL_TRIO PF00650.20 KER30798.1 - 1.7e-19 70.1 0.4 2.4e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KER30798.1 - 0.018 15.2 0.4 0.04 14.1 0.1 1.7 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain DXP_synthase_N PF13292.6 KER30798.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SelR PF01641.18 KER30799.1 - 4.1e-37 126.9 1.1 6.3e-36 123.1 1.1 2.1 1 1 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KER30799.1 - 0.05 13.8 0.1 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KER30799.1 - 0.058 13.1 0.8 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C3HC4_4 PF15227.6 KER30799.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.6 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING MA3 PF02847.17 KER30800.1 - 0.0001 22.3 0.0 0.00089 19.2 0.0 2.5 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KER30800.1 - 0.00044 20.0 0.1 0.00084 19.0 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain DUF825 PF05695.12 KER30800.1 - 0.051 10.7 0.0 0.077 10.1 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) PolyA_pol_RNAbd PF12627.7 KER30800.1 - 0.11 12.3 0.2 0.32 10.8 0.2 1.8 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A DEAD PF00270.29 KER30801.1 - 2.4e-29 102.4 0.0 2.2e-28 99.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER30801.1 - 1.3e-26 93.1 0.1 4.7e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PIG-X PF08320.12 KER30801.1 - 4.1e-14 53.0 0.0 1.4e-13 51.2 0.0 1.9 2 1 0 2 2 2 1 PIG-X / PBN1 ResIII PF04851.15 KER30801.1 - 5.9e-06 26.4 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_pol_Rpc4 PF05132.14 KER30801.1 - 0.00034 21.1 2.2 0.00055 20.4 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 AAA_22 PF13401.6 KER30801.1 - 0.0049 17.1 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KER30801.1 - 0.13 11.5 0.6 0.41 9.9 0.1 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit MRP-S32 PF10210.9 KER30803.1 - 6.2e-09 36.3 0.0 1.2e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 LIM PF00412.22 KER30804.1 - 1.9e-06 28.0 5.5 3.9e-06 27.0 5.5 1.5 1 0 0 1 1 1 1 LIM domain DUF4757 PF15949.5 KER30804.1 - 0.00031 21.2 8.9 0.0013 19.3 8.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) CH PF00307.31 KER30804.1 - 0.0011 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain PDZ PF00595.24 KER30804.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 KER30804.1 - 0.15 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 PDZ domain LRR_8 PF13855.6 KER30805.1 - 2.2e-14 52.9 10.1 2.4e-13 49.6 0.7 3.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KER30805.1 - 3.1e-07 30.6 10.6 0.0052 17.2 0.1 4.9 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) I-set PF07679.16 KER30805.1 - 0.00095 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.6 KER30805.1 - 0.001 19.1 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 KER30805.1 - 0.0021 18.6 0.2 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 KER30805.1 - 0.012 16.0 9.0 17 6.5 0.0 6.9 7 1 0 7 7 7 0 Leucine Rich Repeat Ig_2 PF13895.6 KER30805.1 - 0.032 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain LRRCT PF01463.24 KER30805.1 - 0.06 13.9 0.0 0.23 12.1 0.0 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 KER30805.1 - 0.2 11.8 7.7 1.7 8.9 0.4 4.3 3 0 0 3 3 3 0 Leucine Rich repeat LRRNT PF01462.18 KER30805.1 - 0.63 9.7 2.5 4.2 7.1 1.6 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF2574 PF10836.8 KER30807.1 - 0.13 12.2 0.9 0.22 11.4 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2574) MBD PF01429.19 KER30809.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain RasGAP PF00616.19 KER30811.1 - 3.9e-21 75.7 0.0 9.6e-21 74.4 0.0 1.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KER30811.1 - 3.4e-06 27.3 0.1 0.01 16.0 0.1 2.6 1 1 1 2 2 2 2 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KER30811.1 - 0.02 14.8 0.6 0.31 10.9 0.0 2.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal CheX PF13690.6 KER30811.1 - 0.15 12.3 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Homeodomain PF00046.29 KER30813.1 - 1.1e-11 44.3 13.3 1.1e-08 34.8 1.7 2.5 2 0 0 2 2 2 2 Homeodomain Ets PF00178.22 KER30815.1 - 4.9e-18 65.4 2.9 2.9e-16 59.7 0.1 2.7 3 0 0 3 3 3 2 Ets-domain Alg6_Alg8 PF03155.15 KER30816.1 - 2.1e-135 452.4 30.7 2.8e-135 452.0 30.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Alg6_Alg8 PF03155.15 KER30817.1 - 5.6e-10 38.8 0.0 6.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Exo_endo_phos_2 PF14529.6 KER30817.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Ig_3 PF13927.6 KER30821.1 - 2.2e-09 37.8 1.2 7.6e-05 23.2 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KER30821.1 - 3.6e-08 33.6 0.0 0.0063 16.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER30821.1 - 3.7e-05 23.7 0.1 0.0024 17.9 0.0 3.4 3 1 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 KER30821.1 - 0.0085 16.2 0.0 16 5.7 0.0 3.8 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.17 KER30821.1 - 0.059 13.5 0.1 5.3 7.3 0.0 3.1 3 1 0 3 3 3 0 Immunoglobulin V-set domain RT_RNaseH_2 PF17919.1 KER30823.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER30823.1 - 0.001 19.3 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4483 PF14825.6 KER30824.1 - 1.7e-17 63.6 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Thioredoxin PF00085.20 KER30825.1 - 1.3e-12 47.6 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HCV_NS2 PF01538.18 KER30825.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 Alpha-amylase PF00128.24 KER30828.1 - 1e-23 84.5 0.1 6.4e-20 72.0 0.1 3.0 2 1 0 2 2 2 2 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 KER30828.1 - 3e-23 81.2 0.3 5.4e-23 80.3 0.3 1.4 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus EF-hand_6 PF13405.6 KER30830.1 - 7.9e-08 31.6 0.7 0.0029 17.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KER30830.1 - 6.2e-07 29.8 2.0 1.2e-05 25.7 0.2 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER30830.1 - 0.0017 17.8 3.7 0.0075 15.7 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KER30830.1 - 0.0079 16.0 2.3 0.95 9.4 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain pair Pox_G5 PF04599.12 KER30830.1 - 0.061 12.3 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Poxvirus G5 protein EF-hand_6 PF13405.6 KER30831.1 - 5.8e-08 32.1 3.8 0.00017 21.3 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KER30831.1 - 8.2e-08 32.6 2.5 6.4e-07 29.7 0.7 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER30831.1 - 0.00044 19.6 0.0 0.00044 19.6 0.0 3.9 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 KER30831.1 - 0.066 13.1 5.1 0.38 10.6 0.2 3.3 2 1 1 3 3 3 0 EF-hand domain pair HECT PF00632.25 KER30832.1 - 3e-56 191.2 0.0 2.2e-55 188.3 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) TPR_12 PF13424.6 KER30833.1 - 1.3e-13 51.0 8.7 1.1e-05 25.6 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER30833.1 - 3.1e-09 36.3 0.7 0.024 14.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER30833.1 - 1.1e-07 31.4 1.1 1.9 8.8 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER30833.1 - 8.8e-06 25.4 0.4 0.5 10.5 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER30833.1 - 0.00017 21.2 0.8 13 5.8 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KER30833.1 - 0.00026 20.5 6.5 0.0033 16.9 0.3 2.7 2 1 0 2 2 2 2 MalT-like TPR region RPN7 PF10602.9 KER30833.1 - 0.0026 17.5 0.3 0.0071 16.1 0.1 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 KER30833.1 - 0.02 14.8 3.1 1.2 9.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER30833.1 - 0.042 14.5 1.9 33 5.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KER30833.1 - 0.054 14.2 0.3 3.3 8.5 0.1 3.1 2 1 0 2 2 2 0 Sel1 repeat TPR_14 PF13428.6 KER30833.1 - 0.081 13.8 1.7 22 6.2 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KER30833.1 - 0.24 11.9 2.1 20 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KER30833.1 - 1.5 9.6 15.6 2 9.3 0.5 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Hexokinase_2 PF03727.16 KER30834.1 - 8.7e-80 267.6 0.0 1.1e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KER30834.1 - 4.6e-33 114.8 0.2 7.4e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Hexokinase Carb_anhydrase PF00194.21 KER30835.1 - 6e-46 157.0 0.0 2.4e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 KER30836.1 - 2.4e-11 43.7 0.9 0.00013 21.6 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase 7tm_1 PF00001.21 KER30838.1 - 6.2e-43 147.0 0.0 8e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER30838.1 - 5.3e-15 55.5 2.2 8.1e-15 54.9 2.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER30838.1 - 2.8e-09 37.0 7.6 2.8e-09 37.0 7.6 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 KER30838.1 - 0.0014 18.2 7.0 0.0031 17.1 7.0 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_4 PF13853.6 KER30838.1 - 0.011 15.4 1.0 0.019 14.7 1.0 1.2 1 0 0 1 1 1 0 Olfactory receptor DHR-2 PF06920.13 KER30840.1 - 6.2e-125 417.8 0.0 1e-124 417.1 0.0 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KER30842.1 - 4.3e-12 46.3 0.2 2e-10 40.8 0.2 2.8 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins HTH_39 PF14090.6 KER30842.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4218 PF13960.6 KER30843.1 - 0.00088 18.9 0.1 0.0026 17.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4806 PF16064.5 KER30843.1 - 0.029 14.7 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) KapB PF08810.10 KER30845.1 - 0.032 14.4 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Kinase associated protein B Med20 PF08612.11 KER30846.1 - 1.7e-28 99.5 0.0 2.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RabGAP-TBC PF00566.18 KER30849.1 - 1.4e-37 129.5 0.9 3.6e-27 95.4 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF5466 PF17554.2 KER30849.1 - 0.75 10.0 4.4 1 9.6 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5466) Ig_3 PF13927.6 KER30850.1 - 2.4e-14 53.7 0.0 2.3e-07 31.3 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KER30850.1 - 5.1e-11 42.5 0.0 1.2e-06 28.5 0.0 3.1 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KER30850.1 - 1e-09 38.5 0.4 2.1e-05 24.6 0.0 3.4 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 KER30850.1 - 9.1e-07 29.1 0.2 0.0023 18.3 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain Izumo-Ig PF16706.5 KER30850.1 - 0.00093 19.2 0.1 1.1 9.3 0.0 2.8 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 KER30850.1 - 0.0018 18.5 0.1 0.27 11.5 0.0 3.8 3 2 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 KER30850.1 - 0.0083 16.5 0.0 13 6.3 0.0 3.4 3 2 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 KER30850.1 - 0.022 14.9 0.1 2.5 8.3 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin V-set domain BTD PF09270.10 KER30850.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Vinculin PF01044.19 KER30851.1 - 1.8e-114 384.0 22.7 4.4e-101 339.7 13.4 2.4 1 1 0 2 2 2 2 Vinculin family F_actin_bind PF08919.10 KER30851.1 - 0.0062 16.6 10.3 0.31 11.2 0.1 4.6 4 1 0 4 4 4 1 F-actin binding I_LWEQ PF01608.17 KER30851.1 - 0.016 15.4 1.1 0.016 15.4 1.1 4.3 5 0 0 5 5 5 0 I/LWEQ domain Xpo1 PF08389.12 KER30851.1 - 0.026 14.6 1.8 0.18 11.9 0.1 2.6 2 0 0 2 2 2 0 Exportin 1-like protein Isochorismatase PF00857.20 KER30851.1 - 0.078 13.2 0.3 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 Isochorismatase family HHH_2 PF12826.7 KER30851.1 - 0.16 12.1 0.3 0.53 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4709 PF15821.5 KER30851.1 - 0.22 11.8 4.1 1.1 9.5 1.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) HMW1C_N PF18071.1 KER30851.1 - 0.41 10.4 2.6 2.3 8.0 0.1 2.9 3 0 0 3 3 3 0 HMW1C N-terminal LSDAT_euk PF18139.1 KER30852.1 - 5.7e-28 98.1 2.0 3.9e-16 59.3 0.0 2.8 3 0 0 3 3 3 2 SLOG in TRPM LSDAT_prok PF18171.1 KER30852.1 - 4e-12 45.8 0.2 9.5e-06 25.0 0.2 2.4 2 0 0 2 2 2 2 SLOG in TRPM, prokaryote MCLC PF05934.11 KER30853.1 - 5.9 5.5 5.4 0.54 8.9 0.1 1.9 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) DUF4951 PF16309.5 KER30855.1 - 0.066 13.3 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) MFS_1 PF07690.16 KER30856.1 - 2.4e-19 69.5 36.2 8.7e-19 67.7 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KER30856.1 - 0.00036 20.3 15.8 0.067 12.9 5.1 3.4 3 1 0 3 3 3 2 Ion channel regulatory protein UNC-93 SP24 PF16504.5 KER30856.1 - 0.06 13.4 0.1 9.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Putative virion membrane protein of plant and insect virus ATG22 PF11700.8 KER30856.1 - 0.14 10.8 9.0 0.44 9.1 8.9 1.6 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like LNP1 PF15419.6 KER30858.1 - 0.029 14.6 0.2 0.039 14.2 0.2 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Antistasin PF02822.14 KER30859.1 - 2.8e-06 27.8 26.9 5.6e-05 23.7 9.4 2.4 2 0 0 2 2 2 2 Antistasin family DUF600 PF04634.12 KER30859.1 - 0.02 15.0 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 CLASP_N PF12348.8 KER30860.1 - 9.2e-37 126.8 2.8 3e-33 115.3 0.1 3.8 3 1 1 4 4 4 2 CLASP N terminal RVT_1 PF00078.27 KER30860.1 - 4.6e-13 49.2 0.0 6.8e-06 25.8 0.0 3.0 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ecm29 PF13001.7 KER30860.1 - 0.00036 19.4 0.1 0.064 11.9 0.1 2.4 2 0 0 2 2 2 2 Proteasome stabiliser MMS19_C PF12460.8 KER30860.1 - 0.0063 15.7 1.5 0.18 10.9 0.0 3.3 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 KER30860.1 - 0.026 14.8 4.3 0.23 11.8 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat ENTH PF01417.20 KER30860.1 - 0.026 14.6 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 ENTH domain RTP1_C1 PF10363.9 KER30860.1 - 0.14 12.4 0.1 15 5.8 0.0 3.8 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KER30860.1 - 0.14 12.7 0.0 2.2 8.9 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat IFRD PF05004.13 KER30860.1 - 1.2 8.2 2.8 1 8.4 0.1 2.2 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) QSregVF_b PF12843.7 KER30861.1 - 0.045 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor CRAL_TRIO PF00650.20 KER30863.1 - 6.4e-16 58.5 0.1 8.7e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF739 PF05339.11 KER30863.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF3906 PF13046.6 KER30863.1 - 0.13 12.3 0.0 7.2 6.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3906) IGF2_C PF08365.11 KER30865.1 - 0.0028 17.6 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 2 Insulin-like growth factor II E-peptide DUF3134 PF11332.8 KER30865.1 - 0.0031 17.8 0.0 4.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3134) P16-Arc PF04699.14 KER30865.1 - 0.027 14.9 0.1 1.1 9.7 0.0 2.3 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Adaptin_N PF01602.20 KER30867.1 - 1.7e-151 505.4 11.9 2.1e-151 505.1 11.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KER30867.1 - 1.5e-61 207.2 9.4 5e-60 202.2 0.8 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 KER30867.1 - 6.9e-33 113.1 0.1 2.1e-32 111.5 0.1 1.9 2 0 0 2 2 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 KER30867.1 - 2.3e-17 63.1 7.0 3e-06 27.5 0.2 5.8 2 2 4 6 6 6 4 HEAT repeats Alpha_adaptinC2 PF02883.20 KER30867.1 - 6e-13 49.1 1.2 1.2e-12 48.1 0.3 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.22 KER30867.1 - 1.9e-11 43.2 7.7 0.0077 16.4 0.1 6.3 5 0 0 5 5 5 3 HEAT repeat Cnd3 PF12719.7 KER30867.1 - 2e-07 30.5 2.3 5.2e-05 22.6 0.1 3.0 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KER30867.1 - 0.00028 20.8 6.7 0.62 10.2 0.1 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KER30867.1 - 0.00034 20.2 1.0 0.39 10.2 0.2 3.3 2 2 0 2 2 2 2 CLASP N terminal Mo25 PF08569.11 KER30867.1 - 0.0016 17.8 0.7 0.12 11.7 0.0 2.5 1 1 0 2 2 2 1 Mo25-like HEAT_EZ PF13513.6 KER30867.1 - 0.0028 18.1 4.9 11 6.6 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat Sec7_N PF12783.7 KER30867.1 - 0.0041 17.0 4.6 0.0056 16.6 1.5 2.9 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.10 KER30867.1 - 0.028 14.2 8.6 8 6.2 0.2 4.5 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) DNA_alkylation PF08713.11 KER30867.1 - 0.045 13.5 0.0 0.36 10.5 0.0 2.3 2 1 0 2 2 2 0 DNA alkylation repair enzyme API5 PF05918.11 KER30867.1 - 0.95 8.2 4.9 0.32 9.8 0.1 2.5 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) zf-C4 PF00105.18 KER30868.1 - 1.9e-25 89.1 14.9 4.1e-25 88.0 14.9 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER30868.1 - 1e-08 35.0 0.1 2.5e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Ion_trans_2 PF07885.16 KER30869.1 - 6.3e-31 106.2 27.7 3.9e-16 58.8 10.2 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KER30869.1 - 1.1e-05 24.8 8.1 0.0063 15.8 0.1 2.3 2 0 0 2 2 2 2 Ion transport protein DUF2633 PF11119.8 KER30869.1 - 3.6 7.6 8.2 4.2 7.4 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) FYVE PF01363.21 KER30872.1 - 4.7e-10 39.4 8.5 4.9e-10 39.4 3.9 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-C2H2_9 PF16293.5 KER30872.1 - 0.017 14.9 0.1 0.41 10.5 0.0 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) ACP_PD PF04336.12 KER30872.1 - 0.084 13.3 1.5 1.5 9.3 0.3 2.9 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF5344 PF17279.2 KER30872.1 - 0.096 13.3 0.5 0.34 11.5 0.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5344) zf-RING_UBOX PF13445.6 KER30872.1 - 0.12 12.4 3.3 0.34 11.0 0.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C2H2_4 PF13894.6 KER30872.1 - 0.36 11.8 0.1 0.36 11.8 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger ATP-synt_D PF01813.17 KER30872.1 - 1 9.2 6.6 1.5 8.6 0.0 3.5 2 2 2 4 4 4 0 ATP synthase subunit D zf_C2H2_ZHX PF18387.1 KER30872.1 - 4.9 6.9 6.1 5.6 6.7 0.1 3.4 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain HECT PF00632.25 KER30873.1 - 8.9e-59 199.5 0.0 1.4e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 KER30873.1 - 1e-30 105.2 2.3 1e-30 105.2 2.3 1.9 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD PABP PF00658.18 KER30873.1 - 9.3e-10 38.6 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain TFIIF_alpha PF05793.12 KER30873.1 - 0.2 10.2 28.6 0.48 8.9 28.6 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.9 KER30873.1 - 0.78 8.8 34.2 2.4 7.2 34.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KER30873.1 - 1.2 8.5 25.2 2.3 7.5 25.2 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KER30873.1 - 2 6.6 15.0 3.4 5.8 15.0 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-UBR PF02207.20 KER30873.1 - 3.4 7.9 29.2 0.031 14.4 21.1 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) BUD22 PF09073.10 KER30873.1 - 7.3 5.8 28.9 17 4.6 28.9 1.5 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 KER30874.1 - 9.1e-50 165.6 22.4 1.1e-10 41.9 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER30874.1 - 6.7e-25 87.2 4.3 2.9e-07 30.7 0.2 6.9 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER30874.1 - 9e-11 42.0 0.1 2.3e-05 24.4 0.0 3.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KER30874.1 - 0.0012 17.9 0.2 0.65 8.9 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 KER30874.1 - 0.0019 18.1 0.5 0.27 11.2 0.0 2.7 3 0 0 3 3 3 1 LisH IKI3 PF04762.12 KER30874.1 - 0.0074 14.3 0.3 0.12 10.4 0.0 2.3 3 0 0 3 3 3 1 IKI3 family Nup160 PF11715.8 KER30874.1 - 0.0088 14.7 2.2 1.4 7.5 0.0 4.3 3 2 2 5 5 5 1 Nucleoporin Nup120/160 Reg_prop PF07494.11 KER30874.1 - 0.063 13.5 0.0 5.2 7.6 0.0 3.3 2 0 0 2 2 2 0 Two component regulator propeller PD40 PF07676.12 KER30874.1 - 0.095 12.7 0.0 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KER30874.1 - 0.1 11.9 0.0 22 4.2 0.0 3.0 3 1 0 3 3 3 0 WD40-like domain Proteasome_A_N PF10584.9 KER30874.1 - 0.21 11.3 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature PolC_DP2 PF03833.13 KER30877.1 - 0.14 10.0 1.8 0.19 9.6 1.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 KER30877.1 - 0.43 10.8 13.1 0.1 12.8 9.5 1.8 2 0 0 2 2 2 0 B-box zinc finger CEBP_ZZ PF16366.5 KER30877.1 - 1 9.6 12.6 0.69 10.2 10.2 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain RT_RNaseH PF17917.1 KER30878.1 - 2.1e-33 114.7 0.0 4.8e-33 113.6 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER30878.1 - 1.6e-23 82.6 0.0 4.7e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KER30878.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain WBP-1 PF11669.8 KER30881.1 - 0.021 15.5 0.1 0.74 10.5 0.0 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Rhomboid PF01694.22 KER30881.1 - 0.032 14.2 0.4 0.046 13.7 0.4 1.1 1 0 0 1 1 1 0 Rhomboid family DDE_Tnp_1_assoc PF13808.6 KER30882.1 - 0.027 14.5 0.1 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-associated SIKE PF05769.11 KER30883.1 - 2.5e-26 92.7 4.2 7.2e-26 91.2 4.2 1.7 1 1 0 1 1 1 1 SIKE family NUDE_C PF04880.13 KER30883.1 - 0.0043 17.6 1.1 0.095 13.2 0.2 2.3 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region Herpes_BLRF2 PF05812.12 KER30883.1 - 0.0059 16.7 0.2 0.87 9.7 0.0 2.7 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein PRKG1_interact PF15898.5 KER30883.1 - 0.034 15.0 3.3 0.83 10.6 0.7 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Nas2_N PF18265.1 KER30883.1 - 0.1 12.5 0.2 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 Nas2 N_terminal domain MscS_porin PF12795.7 KER30883.1 - 0.28 10.7 5.3 0.36 10.3 0.5 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ABC_tran_CTD PF16326.5 KER30883.1 - 0.49 10.7 4.5 0.5 10.7 0.0 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 KER30883.1 - 0.82 10.1 6.2 1 9.8 0.3 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KER30883.1 - 2.5 7.4 6.6 0.45 9.8 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) GIT_CC PF16559.5 KER30883.1 - 7.3 6.5 6.9 1.2 9.1 0.1 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nop53 PF07767.11 KER30885.1 - 5.6e-13 49.1 11.0 1.2e-10 41.3 10.6 2.5 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SH3_9 PF14604.6 KER30886.1 - 3.3e-13 49.3 0.1 5.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain LIM PF00412.22 KER30886.1 - 2.6e-12 46.8 8.8 4.1e-12 46.1 8.8 1.3 1 0 0 1 1 1 1 LIM domain SH3_1 PF00018.28 KER30886.1 - 1.4e-11 43.8 0.0 2.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Nebulin PF00880.18 KER30886.1 - 2.7e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Nebulin repeat SH3_2 PF07653.17 KER30886.1 - 2.7e-05 23.7 0.0 9.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain 2OG-FeII_Oxy_2 PF13532.6 KER30888.1 - 1e-09 38.9 0.0 1.5e-08 35.1 0.0 2.0 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily CUB PF00431.20 KER30889.1 - 1.9e-06 28.2 0.0 2.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 CUB domain DUF282 PF03380.14 KER30889.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 CUB PF00431.20 KER30890.1 - 1.1e-21 77.3 0.0 6.1e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 CUB domain CUB PF00431.20 KER30891.1 - 1.1e-31 109.4 0.0 3.8e-21 75.5 0.0 2.0 2 0 0 2 2 2 2 CUB domain CUB PF00431.20 KER30892.1 - 4.9e-23 81.6 0.0 4.8e-09 36.5 0.0 3.1 2 1 1 3 3 3 3 CUB domain DMAP1_like PF17024.5 KER30892.1 - 0.035 14.2 0.1 5.7 7.1 0.0 2.2 1 1 1 2 2 2 0 Putative DMAP1-like DUF1281 PF06924.11 KER30892.1 - 0.15 11.6 0.0 9.2 5.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1281) CobT PF06213.12 KER30893.1 - 0.15 11.4 17.0 0.16 11.3 17.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 KER30893.1 - 0.59 9.4 20.4 0.55 9.5 20.4 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KER30893.1 - 1 8.7 28.7 1 8.8 28.7 1.1 1 0 0 1 1 1 0 SDA1 DUF1115 PF06544.12 KER30893.1 - 2.1 8.5 6.1 2.7 8.1 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) RPA43_OB PF17875.1 KER30893.1 - 2.6 8.7 5.4 4.2 8.0 5.4 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Nop14 PF04147.12 KER30893.1 - 5.7 5.0 33.5 6.5 4.8 33.5 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KER30893.1 - 7.6 4.5 48.5 8.3 4.4 48.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 KER30893.1 - 8.8 6.1 12.9 8.4 6.2 12.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TORC_N PF12884.7 KER30897.1 - 0.00015 22.4 0.0 0.00094 19.9 0.0 2.4 1 0 0 1 1 1 1 Transducer of regulated CREB activity, N terminus Glyoxalase_4 PF13669.6 KER30898.1 - 0.1 12.9 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4042 PF13251.6 KER30900.1 - 3.3e-21 75.8 0.6 1.1e-17 64.3 0.1 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4042) DUF812 PF05667.11 KER30901.1 - 0.00021 20.3 18.3 0.00021 20.3 18.3 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF812) Leu_zip PF15294.6 KER30901.1 - 0.00022 20.9 12.2 0.00022 20.9 12.2 3.1 2 1 1 3 3 3 1 Leucine zipper Cauli_DNA-bind PF03310.13 KER30901.1 - 4.3 7.4 5.0 1.4 9.0 0.3 2.6 2 2 2 4 4 4 0 Caulimovirus DNA-binding protein HMMR_N PF15905.5 KER30901.1 - 8.4 5.8 49.9 3.1 7.2 3.8 3.7 2 2 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Guanylate_cyc PF00211.20 KER30902.1 - 1.2e-51 174.9 0.0 1.7e-43 148.3 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 KER30902.1 - 9.7e-06 25.2 1.4 1.4e-05 24.6 1.4 1.2 1 0 0 1 1 1 1 Heme NO binding associated IMS PF00817.20 KER30902.1 - 0.082 12.9 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 impB/mucB/samB family Pkinase_Tyr PF07714.17 KER30903.1 - 1.3e-24 86.9 0.0 5.8e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER30903.1 - 6.8e-24 84.6 0.0 1.2e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Y1_Tnp PF01797.16 KER30903.1 - 0.039 14.0 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Transposase IS200 like MFS_1 PF07690.16 KER30905.1 - 7.6e-34 117.2 28.0 3.1e-21 75.7 7.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily CDC45 PF02724.14 KER30908.1 - 3.6 5.8 20.6 3.5 5.8 20.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 KER30908.1 - 3.8 6.6 41.6 4.2 6.4 41.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 KER30908.1 - 3.8 7.3 20.5 4.2 7.2 20.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 KER30908.1 - 4.8 6.5 17.9 4.9 6.5 17.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop53 PF07767.11 KER30908.1 - 7.9 5.8 7.8 7.3 5.9 7.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TMEM154 PF15102.6 KER30909.1 - 0.011 15.6 0.3 0.058 13.3 0.3 2.2 1 0 0 1 1 1 0 TMEM154 protein family Ninjurin PF04923.12 KER30909.1 - 0.077 12.9 0.5 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Ninjurin BAF1_ABF1 PF04684.13 KER30911.1 - 0.082 11.9 0.7 0.087 11.9 0.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Adap_comp_sub PF00928.21 KER30913.1 - 2.1e-21 76.5 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KER30913.1 - 4.9e-05 23.3 0.2 7.5e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Spc29 PF17082.5 KER30915.1 - 0.01 15.7 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 CLZ PF16526.5 KER30915.1 - 0.12 12.8 1.7 0.55 10.6 0.2 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PH_8 PF15409.6 KER30916.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain TPD52 PF04201.15 KER30919.1 - 2.9e-24 85.5 0.8 4.1e-24 85.0 0.8 1.2 1 0 0 1 1 1 1 Tumour protein D52 family IL12 PF03039.14 KER30919.1 - 0.015 14.6 0.2 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Peptidase_M32 PF02074.15 KER30919.1 - 0.025 13.4 0.4 0.031 13.0 0.4 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF5106 PF17127.4 KER30919.1 - 0.036 14.3 0.2 0.061 13.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5106) Cas3_C PF18395.1 KER30919.1 - 0.089 13.3 0.4 1.8 9.1 0.1 2.2 1 1 0 2 2 2 0 Cas3 C-terminal domain Enkurin PF13864.6 KER30919.1 - 0.1 13.1 2.4 0.17 12.4 0.5 2.0 2 0 0 2 2 2 0 Calmodulin-binding DUF883 PF05957.13 KER30919.1 - 0.25 12.0 1.8 8.7 7.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-C4H2 PF10146.9 KER30919.1 - 0.39 11.0 2.3 0.57 10.5 2.3 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein ribosomal_L24 PF17136.4 KER30920.1 - 0.013 15.9 0.6 4.1 7.9 0.1 2.3 1 1 1 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF126 PF01989.16 KER30920.1 - 0.22 11.4 0.6 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Aconitase X swivel domain Piwi PF02171.17 KER30921.1 - 2.1e-115 385.2 0.0 3e-115 384.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KER30921.1 - 1.2e-31 108.8 0.0 3.6e-31 107.2 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 KER30921.1 - 2.4e-27 95.4 0.5 4.1e-27 94.7 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KER30921.1 - 2.4e-26 93.0 0.1 8e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KER30921.1 - 5.9e-23 80.3 0.1 1.3e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KER30921.1 - 7.1e-14 51.9 0.7 1.5e-13 50.9 0.1 1.9 2 0 0 2 2 2 1 Argonaute linker 2 domain zf-H2C2_2 PF13465.6 KER30923.1 - 3.2e-27 93.7 27.8 1.2e-08 35.0 0.2 5.0 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER30923.1 - 6.5e-21 73.6 34.2 1e-06 28.9 1.0 5.1 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER30923.1 - 4.4e-15 55.1 28.9 0.00099 19.8 2.5 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER30923.1 - 2.4e-12 46.8 6.0 0.0025 18.1 0.4 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KER30923.1 - 7.5e-06 25.7 15.4 0.29 11.1 0.1 4.9 4 0 0 4 4 4 4 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KER30923.1 - 8.5e-06 25.6 25.9 0.0054 16.7 1.3 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KER30923.1 - 3.1e-05 23.6 21.2 0.024 14.4 4.0 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 KER30923.1 - 4.8e-05 22.9 7.5 0.083 12.5 0.1 4.5 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KER30923.1 - 0.00033 21.3 4.5 0.14 12.9 0.3 2.8 1 1 1 2 2 2 2 zinc-ribbon family DZR PF12773.7 KER30923.1 - 0.0074 16.3 9.7 1.1 9.3 9.7 3.3 1 1 0 1 1 1 1 Double zinc ribbon XPA_N PF01286.18 KER30923.1 - 0.0082 16.2 10.1 5.2 7.2 0.2 4.4 4 0 0 4 4 4 1 XPA protein N-terminal zf-met PF12874.7 KER30923.1 - 0.013 15.8 17.3 0.52 10.8 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KER30923.1 - 0.034 14.3 13.5 0.74 10.0 2.8 4.4 2 1 3 5 5 5 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KER30923.1 - 0.064 13.2 6.6 1.2 9.1 0.7 4.2 3 1 0 3 3 3 0 zinc-ribbon domain zf-MYST PF17772.1 KER30923.1 - 0.27 10.9 3.4 30 4.3 0.1 3.8 2 2 2 4 4 4 0 MYST family zinc finger domain DUF2256 PF10013.9 KER30923.1 - 0.38 10.9 5.2 31 4.8 0.0 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.6 KER30923.1 - 0.46 10.4 8.4 4.4 7.3 0.1 3.6 4 0 0 4 4 3 0 Probable zinc-ribbon domain DUF3268 PF11672.8 KER30923.1 - 0.79 10.1 4.7 0.83 10.0 0.5 2.3 1 1 2 3 3 3 0 zinc-finger-containing domain CpXC PF14353.6 KER30923.1 - 0.9 9.6 6.1 6.5 6.8 0.0 3.7 1 1 3 4 4 4 0 CpXC protein ADK_lid PF05191.14 KER30923.1 - 1.4 9.0 13.7 0.15 12.1 0.9 3.5 2 1 2 4 4 4 0 Adenylate kinase, active site lid LIM PF00412.22 KER30923.1 - 2.2 8.6 11.5 11 6.4 2.4 3.4 2 1 0 2 2 2 0 LIM domain zf-AN1 PF01428.16 KER30923.1 - 2.3 8.5 17.4 9.8 6.4 0.1 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger zf-RING_7 PF02591.15 KER30923.1 - 8.2 6.7 11.4 13 6.1 0.0 4.6 5 0 0 5 5 4 0 C4-type zinc ribbon domain Tetraspanin PF00335.20 KER30924.1 - 4.4e-26 92.0 16.8 5.2e-26 91.8 16.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 KER30925.1 - 1.5e-17 64.1 7.3 1.8e-17 63.8 7.3 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF5083 PF16890.5 KER30925.1 - 0.064 13.0 1.0 0.11 12.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) EMC3_TMCO1 PF01956.16 KER30925.1 - 0.57 9.9 3.4 6.6 6.4 0.2 2.4 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Tetraspanin PF00335.20 KER30926.1 - 1.6e-24 86.9 10.2 2e-24 86.6 10.2 1.0 1 0 0 1 1 1 1 Tetraspanin family Zw10 PF06248.13 KER30927.1 - 7e-09 34.8 9.3 3.3e-08 32.5 4.6 3.2 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Thioredoxin_6 PF13848.6 KER30929.1 - 5.2e-22 78.6 0.1 9.9e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain B56 PF01603.20 KER30930.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Coatomer_WDAD PF04053.14 KER30931.1 - 1.7e-146 488.8 0.0 5.3e-146 487.2 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KER30931.1 - 5.2e-42 141.0 2.8 2.4e-08 34.5 0.0 7.9 9 0 0 9 9 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER30931.1 - 1.2e-06 28.8 0.9 3 8.2 0.1 5.2 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER30931.1 - 0.00035 19.4 4.7 1.9 7.0 0.0 4.5 2 2 3 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KER30931.1 - 0.0093 16.0 0.0 5.4 7.1 0.0 3.9 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KER30931.1 - 0.01 14.6 0.1 9.3 4.9 0.0 3.4 2 1 2 4 4 4 0 Nup133 N terminal like BUD22 PF09073.10 KER30931.1 - 0.015 14.7 15.5 0.023 14.0 15.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KER30931.1 - 0.017 13.4 22.0 0.024 12.9 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KER30931.1 - 0.021 14.4 15.1 0.032 13.8 15.1 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 KER30931.1 - 0.11 10.6 34.0 0.2 9.7 34.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi WD40_like PF17005.5 KER30931.1 - 0.21 10.9 0.0 21 4.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Mpp10 PF04006.12 KER30931.1 - 1.7 7.0 25.3 2.6 6.4 25.3 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4820 PF16091.5 KER30931.1 - 5.7 6.2 7.1 9.5 5.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PI3_PI4_kinase PF00454.27 KER30932.1 - 5.3e-35 121.4 0.0 6.6e-23 81.8 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KER30932.1 - 5.5e-06 25.9 0.2 1e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) WI12 PF07107.11 KER30932.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Wound-induced protein WI12 Cpn10 PF00166.21 KER30936.1 - 6e-26 90.3 0.1 2.2e-24 85.3 0.1 2.0 1 1 0 1 1 1 1 Chaperonin 10 Kd subunit Peptidase_S9 PF00326.21 KER30939.1 - 5.7e-46 156.7 0.0 9e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KER30939.1 - 4.1e-06 26.6 0.1 5.6e-05 22.9 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KER30939.1 - 2.2e-05 23.8 1.0 0.00074 18.9 0.3 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DPPIV_N PF00930.21 KER30939.1 - 3.2e-05 22.8 0.2 0.00032 19.6 0.1 2.4 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Esterase PF00756.20 KER30939.1 - 4.4e-05 23.3 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KER30939.1 - 0.00028 21.6 0.2 0.00071 20.2 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 KER30939.1 - 0.00074 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_3 PF07859.13 KER30939.1 - 0.0018 18.2 0.0 0.0054 16.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KER30939.1 - 0.0019 18.0 0.0 0.84 9.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 KER30939.1 - 0.018 13.8 0.1 0.16 10.6 0.1 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KER30939.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3141 PF11339.8 KER30939.1 - 0.044 12.2 0.0 0.083 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DLH PF01738.18 KER30939.1 - 0.059 12.9 0.0 0.6 9.6 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Tannase PF07519.11 KER30939.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase StbA PF06406.11 KER30939.1 - 0.18 11.0 0.1 17 4.5 0.0 2.1 2 0 0 2 2 2 0 StbA protein Ank_4 PF13637.6 KER30941.1 - 6.6e-39 131.8 9.8 2.4e-10 40.7 0.0 8.2 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER30941.1 - 8.7e-39 132.0 6.9 1.6e-15 57.4 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER30941.1 - 9.8e-34 111.6 10.3 0.00026 21.2 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KER30941.1 - 9.1e-31 105.5 11.7 1e-06 28.9 0.0 8.1 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KER30941.1 - 6.1e-26 89.7 5.6 3.4e-05 24.1 0.1 7.9 7 1 0 7 7 7 6 Ankyrin repeat SOCS_box PF07525.16 KER30941.1 - 3.4e-09 36.9 1.5 8.8e-09 35.6 1.5 1.7 1 0 0 1 1 1 1 SOCS box GIY-YIG PF01541.24 KER30944.1 - 0.038 14.3 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 GIY-YIG catalytic domain FixO PF02433.15 KER30944.1 - 0.73 9.2 3.7 7.8 5.9 0.1 3.0 2 1 1 3 3 3 0 Cytochrome C oxidase, mono-heme subunit/FixO Tetraspanin PF00335.20 KER30945.1 - 4.7e-27 95.2 0.4 5.9e-27 94.9 0.4 1.1 1 0 0 1 1 1 1 Tetraspanin family MFP2b PF12150.8 KER30945.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Cytosolic motility protein PTB PF08416.13 KER30947.1 - 4.3e-20 72.2 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.24 KER30947.1 - 2.8e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PID_2 PF14719.6 KER30947.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.23 KER30947.1 - 0.002 18.2 0.1 0.004 17.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) IMPa_N_2 PF18650.1 KER30947.1 - 0.17 11.1 0.2 1.1 8.4 0.1 2.0 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Tup_N PF08581.10 KER30949.1 - 0.0076 16.5 3.9 0.07 13.4 0.1 2.7 2 0 0 2 2 2 1 Tup N-terminal Syntaxin PF00804.25 KER30949.1 - 0.012 15.3 1.7 5.5 6.6 0.0 3.1 2 1 0 2 2 2 0 Syntaxin Laminin_II PF06009.12 KER30949.1 - 0.014 15.4 3.2 0.39 10.7 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II EzrA PF06160.12 KER30949.1 - 0.036 12.2 3.0 0.075 11.2 0.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 KER30949.1 - 0.1 13.2 2.9 3.6 8.2 0.3 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 KER30949.1 - 0.13 10.2 0.1 1.2 7.0 0.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MAAL_N PF05034.13 KER30949.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Spc7 PF08317.11 KER30949.1 - 0.44 9.4 3.0 7.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KER30949.1 - 3.6 8.1 7.5 3.2 8.3 0.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region ArsA_HSP20 PF17886.1 KER30950.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Tropomyosin PF00261.20 KER30952.1 - 1.5e-86 289.6 84.1 8.1e-83 277.4 57.2 2.2 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 KER30952.1 - 1.8e-30 105.9 79.2 2.2e-27 96.0 42.7 4.0 2 1 2 4 4 4 3 Tropomyosin like MscS_porin PF12795.7 KER30952.1 - 7.2e-05 22.4 61.0 0.00031 20.4 49.1 2.7 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF724 PF05266.14 KER30952.1 - 0.00052 19.9 21.6 0.00052 19.9 21.6 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF724) ERM PF00769.19 KER30952.1 - 0.0022 17.9 77.5 0.0099 15.7 25.7 2.6 2 1 0 2 2 2 2 Ezrin/radixin/moesin family Lebercilin PF15619.6 KER30952.1 - 0.0035 17.0 64.6 0.043 13.5 25.0 3.6 1 1 2 3 3 3 3 Ciliary protein causing Leber congenital amaurosis disease Cep57_MT_bd PF06657.13 KER30952.1 - 0.0047 17.3 3.6 0.0047 17.3 3.6 5.2 2 2 3 5 5 5 1 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KER30952.1 - 0.0061 16.6 30.9 0.27 11.3 11.2 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF1664) FPP PF05911.11 KER30952.1 - 0.011 14.0 58.3 0.16 10.1 33.2 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil BORCS7 PF16088.5 KER30952.1 - 0.095 13.0 0.4 0.095 13.0 0.4 4.5 1 1 3 5 5 5 0 BLOC-1-related complex sub-unit 7 SNARE PF05739.19 KER30952.1 - 0.11 12.5 1.5 1.8 8.6 0.2 3.0 2 0 0 2 2 2 0 SNARE domain DUF4472 PF14739.6 KER30952.1 - 0.15 12.8 54.1 0.46 11.2 14.9 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Fib_alpha PF08702.10 KER30952.1 - 0.22 11.7 35.6 1 9.5 2.5 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 KER30952.1 - 0.27 9.8 51.9 0.079 11.6 29.1 2.4 1 1 1 2 2 2 0 AAA domain Nuc_N PF14448.6 KER30952.1 - 0.31 10.9 4.4 16 5.5 0.3 3.2 2 0 0 2 2 2 0 Nuclease N terminal ATG16 PF08614.11 KER30952.1 - 0.32 11.2 72.8 0.047 13.9 26.0 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 KER30952.1 - 0.49 7.8 60.6 0.62 7.5 25.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spectrin PF00435.21 KER30952.1 - 0.54 10.8 51.2 4.6 7.8 6.5 4.4 1 1 3 4 4 4 0 Spectrin repeat TPR_MLP1_2 PF07926.12 KER30952.1 - 0.57 10.2 71.4 0.098 12.7 19.6 4.2 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 KER30952.1 - 0.58 10.2 40.3 0.078 13.0 9.6 4.0 1 1 5 6 6 6 0 Laminin Domain II WD40_alt PF14077.6 KER30952.1 - 0.81 9.6 5.6 5.2 7.0 0.3 3.5 2 1 0 2 2 2 0 Alternative WD40 repeat motif HOOK PF05622.12 KER30952.1 - 1.2 7.2 57.8 1.8 6.6 20.9 2.9 1 1 1 2 2 2 0 HOOK protein Spc7 PF08317.11 KER30952.1 - 1.3 7.8 65.4 0.053 12.4 22.7 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KER30952.1 - 1.7 9.0 57.5 0.64 10.4 20.8 2.8 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 KER30952.1 - 3.7 8.0 35.7 0.8 10.1 1.3 5.9 3 2 4 7 7 7 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 KER30952.1 - 3.8 7.9 59.8 0.079 13.3 25.3 3.8 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 KER30952.1 - 5.7 7.1 57.8 1.6 8.9 17.0 4.6 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase DUF4686 PF15742.5 KER30952.1 - 5.9 5.9 55.9 24 3.9 34.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF16 PF01519.16 KER30952.1 - 7 7.2 41.1 0.71 10.4 8.3 4.8 1 1 4 5 5 4 0 Protein of unknown function DUF16 T3SSipB PF16535.5 KER30952.1 - 8.6 6.8 45.9 2 8.9 6.3 4.1 1 1 3 4 4 4 0 Type III cell invasion protein SipB HemX PF04375.14 KER30952.1 - 9.4 5.4 46.6 4.6 6.4 4.9 3.5 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 KER30952.1 - 9.7 5.7 41.0 22 4.5 17.8 2.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit F-box PF00646.33 KER30953.1 - 1 9.3 4.1 14 5.7 0.0 3.7 3 1 0 3 3 3 0 F-box domain Jas PF16135.5 KER30959.1 - 3.1 8.0 6.3 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling Pox_A11 PF05061.13 KER30960.1 - 0.22 10.8 2.7 0.36 10.1 2.7 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein wnt PF00110.19 KER30961.1 - 1.7e-91 307.0 0.0 9e-50 170.0 0.0 2.4 2 1 0 2 2 2 2 wnt family MamL-1 PF09596.10 KER30961.1 - 0.0094 16.2 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 MamL-1 domain AAA PF00004.29 KER30962.1 - 2.4e-53 180.1 0.1 2.9e-41 141.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER30962.1 - 1.4e-11 44.0 0.0 3.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KER30962.1 - 1.8e-06 28.5 0.0 0.025 14.9 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 KER30962.1 - 2.2e-06 27.1 0.0 0.0091 15.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KER30962.1 - 2.8e-06 27.7 0.1 0.0045 17.3 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KER30962.1 - 3.6e-06 27.6 0.0 0.09 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KER30962.1 - 7.8e-06 25.6 0.2 3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 KER30962.1 - 1.1e-05 25.2 0.4 0.02 14.7 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER30962.1 - 1.7e-05 24.9 0.3 0.002 18.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KER30962.1 - 2e-05 24.8 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KER30962.1 - 4.6e-05 23.6 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KER30962.1 - 0.00011 22.0 0.1 0.094 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KER30962.1 - 0.00014 21.8 0.0 0.091 12.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KER30962.1 - 0.00017 21.1 0.7 0.0082 15.5 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 KER30962.1 - 0.00025 21.2 0.0 0.00094 19.3 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.22 KER30962.1 - 0.0013 19.1 0.0 0.083 13.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 KER30962.1 - 0.0019 17.6 0.2 0.0078 15.6 0.1 2.1 3 0 0 3 3 2 1 KaiC AAA_14 PF13173.6 KER30962.1 - 0.0022 18.0 0.0 0.8 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KER30962.1 - 0.003 17.4 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KER30962.1 - 0.0047 16.8 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KER30962.1 - 0.0085 15.2 0.0 0.76 8.8 0.0 2.8 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KER30962.1 - 0.01 15.4 0.2 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KER30962.1 - 0.012 15.4 0.1 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KER30962.1 - 0.013 15.5 0.1 21 4.9 0.1 3.8 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea IPT PF01745.16 KER30962.1 - 0.014 14.8 0.2 0.6 9.5 0.0 2.8 3 0 0 3 3 3 0 Isopentenyl transferase AAA_19 PF13245.6 KER30962.1 - 0.015 15.6 0.2 1.2 9.5 0.1 3.5 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KER30962.1 - 0.021 14.7 0.2 3.6 7.5 0.0 3.4 4 0 0 4 4 3 0 NACHT domain AAA_7 PF12775.7 KER30962.1 - 0.027 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KER30962.1 - 0.064 13.0 0.1 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KER30962.1 - 0.091 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KER30962.1 - 0.12 12.1 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 KER30962.1 - 0.14 12.4 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rad17 PF03215.15 KER30962.1 - 0.16 11.9 0.0 10 6.0 0.0 2.8 2 1 1 3 3 3 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 KER30962.1 - 0.16 11.7 0.0 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 KER30962.1 - 0.19 12.0 0.0 22 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF5641 PF18701.1 KER30964.1 - 9.7e-10 38.5 0.1 1.9e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5641) E1-E2_ATPase PF00122.20 KER30966.1 - 2.5e-26 92.3 1.4 5.4e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KER30966.1 - 6.4e-17 62.5 0.0 2.2e-09 37.9 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KER30966.1 - 2e-16 60.2 3.2 2e-16 60.2 3.2 2.5 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 KER30966.1 - 1.5e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2681 PF10883.8 KER30969.1 - 0.97 9.9 4.2 1.9 9.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Qn_am_d_aIV PF09100.10 KER30970.1 - 0.036 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV zf-C2H2 PF00096.26 KER30972.1 - 8.9e-23 79.4 49.8 1.1e-05 25.6 2.7 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER30972.1 - 4.3e-19 68.0 51.5 6.7e-07 29.5 0.9 7.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER30972.1 - 1.9e-16 59.3 47.4 0.0019 18.9 2.4 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER30972.1 - 1.7e-05 24.9 33.5 0.19 12.1 0.6 6.8 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KER30972.1 - 0.0032 17.7 22.7 0.49 10.7 5.2 3.8 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KER30972.1 - 0.019 14.9 45.9 0.32 11.1 1.1 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER30972.1 - 0.029 14.6 30.7 0.3 11.4 0.5 4.9 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KER30972.1 - 0.089 12.8 30.4 0.48 10.5 1.3 5.8 4 1 2 6 6 6 0 BED zinc finger zinc_ribbon_15 PF17032.5 KER30972.1 - 0.13 13.1 15.3 1.9 9.3 1.4 3.6 1 1 2 3 3 3 0 zinc-ribbon family zf-LYAR PF08790.11 KER30972.1 - 0.29 11.1 27.0 1.8 8.6 0.1 5.4 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 KER30972.1 - 0.38 10.9 22.6 4.7 7.4 4.6 5.4 4 2 1 5 5 5 0 Zinc ribbon domain CpXC PF14353.6 KER30972.1 - 1.7 8.7 17.0 3.2 7.8 3.5 4.2 1 1 1 3 3 3 0 CpXC protein Yippee-Mis18 PF03226.14 KER30972.1 - 1.7 8.9 12.7 3 8.1 0.3 3.1 1 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly XPA_N PF01286.18 KER30972.1 - 1.7 8.8 20.9 5.3 7.2 0.3 5.8 6 0 0 6 6 6 0 XPA protein N-terminal zf-C2HE PF16278.5 KER30972.1 - 2.6 8.5 35.2 7.3 7.1 2.5 6.5 1 1 5 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KER30972.1 - 2.7 8.3 26.6 7.9 6.7 0.2 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 KER30972.1 - 5.2 7.8 22.4 21 5.8 0.5 5.1 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KER30972.1 - 5.3 6.7 21.0 3.4 7.3 0.0 5.1 6 0 0 6 6 5 0 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 KER30972.1 - 6.9 7.0 10.7 0.084 13.2 1.0 2.6 2 1 0 2 2 2 0 zinc-finger-containing domain Evr1_Alr PF04777.13 KER30972.1 - 9.7 6.7 22.1 3.3 8.2 0.7 5.3 1 1 3 4 4 4 0 Erv1 / Alr family A_deaminase PF00962.22 KER30973.1 - 1.5e-108 363.0 0.1 2.3e-108 362.4 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase OTU PF02338.19 KER30974.1 - 0.0077 16.7 0.1 0.0081 16.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Sulfotransfer_4 PF17784.1 KER30976.1 - 1.9e-57 194.6 0.1 2.4e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER30976.1 - 8.7e-07 29.5 1.2 9.1e-06 26.2 1.2 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER30976.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain BID PF06393.11 KER30977.1 - 0.011 15.3 3.7 0.023 14.3 3.7 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) REV1_C PF16727.5 KER30977.1 - 0.29 11.5 2.5 0.7 10.3 2.0 1.9 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain ATP-synt_B PF00430.18 KER30977.1 - 5.1 7.2 17.0 11 6.2 17.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) FapA PF03961.13 KER30977.1 - 10 4.6 9.2 15 4.1 9.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AhpC-TSA PF00578.21 KER30978.1 - 5.6e-38 129.6 0.0 7.8e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KER30978.1 - 2.8e-15 56.3 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KER30978.1 - 1.8e-12 46.9 0.0 3.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KER30978.1 - 0.022 14.7 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC TRM13 PF05206.14 KER30979.1 - 5.1e-68 229.4 0.0 6.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.6 KER30979.1 - 0.49 10.4 4.6 6.3 6.8 4.6 2.5 1 1 0 1 1 1 0 Methyltransferase domain PRELI PF04707.14 KER30981.1 - 0.00058 19.7 0.0 0.00087 19.1 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Cadherin PF00028.17 KER30982.1 - 2.2e-56 188.3 2.4 1.4e-15 57.5 0.0 8.9 7 4 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 KER30982.1 - 0.00067 19.4 0.0 3 7.7 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Homeodomain PF00046.29 KER30985.1 - 8.7e-21 73.5 7.6 2.7e-20 72.0 7.6 1.9 1 0 0 1 1 1 1 Homeodomain Engrail_1_C_sig PF10525.9 KER30985.1 - 5.7e-13 47.8 0.0 1.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Engrailed homeobox C-terminal signature domain CENP-B_N PF04218.13 KER30985.1 - 0.0039 16.8 0.5 0.0039 16.8 0.5 2.0 2 1 0 2 2 2 1 CENP-B N-terminal DNA-binding domain Homeobox_KN PF05920.11 KER30985.1 - 0.016 15.1 0.7 0.016 15.1 0.7 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF2244 PF10003.9 KER30985.1 - 0.088 12.5 0.3 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Pkinase PF00069.25 KER30986.1 - 9.6e-63 212.0 0.0 2.3e-62 210.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER30986.1 - 1.2e-43 149.3 0.0 2.6e-43 148.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase MIT PF04212.18 KER30986.1 - 1.7e-10 40.8 4.9 4.4e-10 39.5 4.9 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain APH PF01636.23 KER30986.1 - 0.0013 18.7 0.1 0.0059 16.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KER30986.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER30986.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER30986.1 - 0.047 12.5 0.0 0.13 11.0 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KER30986.1 - 0.057 12.4 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BRK PF07533.16 KER30988.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 BRK domain Lectin_leg-like PF03388.13 KER30990.1 - 2e-67 226.9 0.0 2.4e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KER30990.1 - 1.1e-07 32.0 0.0 2e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KER30990.1 - 0.00025 20.7 0.0 0.011 15.3 0.0 2.1 1 1 0 1 1 1 1 Legume lectin domain Sugar_tr PF00083.24 KER30991.1 - 3e-18 65.9 12.6 7.5e-12 44.8 0.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KER30991.1 - 6.2e-15 55.0 16.0 6.2e-15 55.0 16.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily RVT_1 PF00078.27 KER30992.1 - 2.9e-14 53.1 0.0 4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fringe PF02434.16 KER30993.1 - 6.4e-10 38.9 0.2 2.7e-09 36.8 0.2 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KER30993.1 - 2.1e-05 24.4 0.2 0.14 11.9 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 KER30994.1 - 1.1e-11 44.7 0.1 6.7e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KER30994.1 - 5.5e-06 26.3 0.1 0.092 12.6 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase DUF604 PF04646.12 KER30994.1 - 0.025 14.0 0.2 0.036 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF4549 PF15082.6 KER30997.1 - 2.4e-44 150.6 0.7 2.4e-44 150.6 0.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4549) DUF2634 PF10934.8 KER30997.1 - 0.5 10.5 3.3 1.2 9.3 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) DUF4407 PF14362.6 KER30997.1 - 0.51 9.6 31.1 0.45 9.8 15.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) E1-E2_ATPase PF00122.20 KER30998.1 - 3.7e-17 62.4 1.5 5.3e-17 61.9 0.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KER30998.1 - 1.5e-14 53.4 0.0 2.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Josephin PF02099.17 KER30999.1 - 6.6e-51 172.7 0.4 6.6e-51 172.7 0.4 1.6 2 0 0 2 2 2 1 Josephin UIM PF02809.20 KER30999.1 - 0.0058 16.5 15.2 0.58 10.2 1.5 4.1 3 0 0 3 3 3 3 Ubiquitin interaction motif DUF1939 PF09154.10 KER30999.1 - 0.21 11.8 0.4 0.54 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) PRAP PF15314.6 KER30999.1 - 3.1 8.3 5.2 3.1 8.3 1.2 2.8 3 0 0 3 3 3 0 Proline-rich acidic protein 1, pregnancy-specific uterine Radial_spoke PF04712.12 KER31000.1 - 1.7e-11 43.8 0.1 1.7e-05 24.0 0.0 3.0 2 1 0 3 3 3 3 Radial spokehead-like protein DUF3506 PF12014.8 KER31000.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) PRF PF06875.11 KER31002.1 - 0.079 12.4 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF FAD_binding_1 PF00667.20 KER31003.1 - 4.6e-20 72.1 0.0 8.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KER31003.1 - 5.2e-10 39.9 0.0 2e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KER31003.1 - 0.004 17.3 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain HTH_3 PF01381.22 KER31004.1 - 5.6e-13 48.7 0.8 1.1e-12 47.8 0.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 KER31004.1 - 4.4e-10 39.9 0.1 1.3e-09 38.3 0.1 1.8 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 KER31004.1 - 0.00017 21.9 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KER31004.1 - 0.00042 20.3 0.5 0.00081 19.4 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain pXO2-34 PF17362.2 KER31004.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function TPR_MLP1_2 PF07926.12 KER31006.1 - 0.00011 22.3 24.4 0.011 15.8 3.4 4.2 3 2 1 4 4 4 2 TPR/MLP1/MLP2-like protein OmpH PF03938.14 KER31006.1 - 0.00015 22.2 11.9 0.0039 17.5 1.4 2.8 1 1 2 3 3 3 2 Outer membrane protein (OmpH-like) SHE3 PF17078.5 KER31006.1 - 0.0006 19.6 21.2 0.059 13.1 5.6 2.8 1 1 2 3 3 3 2 SWI5-dependent HO expression protein 3 Prefoldin_2 PF01920.20 KER31006.1 - 0.0013 18.7 19.7 0.008 16.1 1.2 4.0 4 0 0 4 4 4 2 Prefoldin subunit APG6_N PF17675.1 KER31006.1 - 0.0014 19.1 24.4 0.38 11.3 3.1 3.1 1 1 2 3 3 3 3 Apg6 coiled-coil region Spc7 PF08317.11 KER31006.1 - 0.0037 16.2 18.1 0.17 10.7 8.9 2.3 1 1 2 3 3 3 3 Spc7 kinetochore protein DUF4201 PF13870.6 KER31006.1 - 0.0043 16.8 19.1 0.038 13.7 2.9 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) DUF4164 PF13747.6 KER31006.1 - 0.0045 17.2 19.6 0.0058 16.9 0.9 4.0 4 1 1 5 5 3 2 Domain of unknown function (DUF4164) DUF5082 PF16888.5 KER31006.1 - 0.0065 16.7 16.7 0.39 11.0 2.1 3.5 2 2 1 3 3 3 1 Domain of unknown function (DUF5082) CCDC106 PF15794.5 KER31006.1 - 0.0072 16.1 19.8 0.056 13.1 0.1 3.1 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 106 FapA PF03961.13 KER31006.1 - 0.013 14.1 13.6 0.11 11.0 1.4 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF641 PF04859.12 KER31006.1 - 0.014 15.8 14.6 0.27 11.6 5.8 3.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KER31006.1 - 0.014 14.8 11.7 0.14 11.5 11.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 KER31006.1 - 0.018 15.2 22.8 0.04 14.1 3.6 3.9 2 2 2 4 4 4 0 Tropomyosin like CLZ PF16526.5 KER31006.1 - 0.02 15.2 0.4 0.02 15.2 0.4 3.9 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 KER31006.1 - 0.022 14.8 13.9 0.43 10.6 1.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KER31006.1 - 0.038 14.4 17.9 0.087 13.3 8.9 2.8 2 1 0 2 2 2 0 Snapin/Pallidin Lectin_N PF03954.14 KER31006.1 - 0.038 13.7 11.4 4.8 6.9 0.4 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain APG17 PF04108.12 KER31006.1 - 0.04 13.0 13.5 0.071 12.2 12.7 1.8 1 1 0 1 1 1 0 Autophagy protein Apg17 AKNA PF12443.8 KER31006.1 - 0.04 14.6 2.5 0.04 14.6 2.5 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor NPV_P10 PF05531.12 KER31006.1 - 0.06 13.8 5.3 4.3 7.9 0.0 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KER31006.1 - 0.063 13.9 17.9 1.5 9.5 1.7 4.3 4 0 0 4 4 4 0 SlyX DUF724 PF05266.14 KER31006.1 - 0.077 12.8 12.5 0.22 11.3 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KER31006.1 - 0.11 12.9 18.5 0.2 12.1 0.8 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KER31006.1 - 0.11 12.5 26.0 0.78 9.8 4.3 3.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KER31006.1 - 0.11 12.7 12.7 1 9.6 0.2 4.1 3 1 1 4 4 3 0 ABC transporter C-terminal domain DivIC PF04977.15 KER31006.1 - 0.13 12.0 18.2 0.44 10.4 0.2 3.5 4 0 0 4 4 3 0 Septum formation initiator Seryl_tRNA_N PF02403.22 KER31006.1 - 0.17 12.1 20.1 0.47 10.7 2.1 3.5 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 KER31006.1 - 0.18 10.7 19.5 1.1 8.0 11.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Cep57_MT_bd PF06657.13 KER31006.1 - 0.19 12.2 18.1 2.5 8.6 1.8 4.1 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 JIP_LZII PF16471.5 KER31006.1 - 0.25 11.5 20.7 4.5 7.5 2.1 4.2 2 2 2 4 4 4 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 KER31006.1 - 0.26 11.7 25.4 1.3 9.5 2.7 3.6 2 2 1 3 3 3 0 Cell division protein ZapB DUF3793 PF12672.7 KER31006.1 - 0.31 11.1 1.9 1.5 8.9 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) DASH_Spc19 PF08287.11 KER31006.1 - 0.39 10.6 27.7 0.058 13.3 12.6 3.2 1 1 2 4 4 4 0 Spc19 V_ATPase_I PF01496.19 KER31006.1 - 0.42 8.5 12.7 0.56 8.1 5.8 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF722 PF05263.11 KER31006.1 - 0.42 10.8 6.1 0.3 11.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF722) WXG100 PF06013.12 KER31006.1 - 0.43 10.8 8.8 21 5.4 0.1 4.1 4 0 0 4 4 4 0 Proteins of 100 residues with WXG bZIP_1 PF00170.21 KER31006.1 - 0.45 10.6 19.8 0.45 10.7 2.2 4.0 2 2 2 4 4 3 0 bZIP transcription factor Prefoldin PF02996.17 KER31006.1 - 0.47 10.4 13.8 6.6 6.7 0.6 4.2 4 0 0 4 4 4 0 Prefoldin subunit ATG16 PF08614.11 KER31006.1 - 0.65 10.2 25.8 0.15 12.2 15.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.9 KER31006.1 - 0.75 9.7 21.4 4.6 7.1 6.4 3.6 2 2 2 4 4 4 0 Axonemal dynein light chain TACC_C PF05010.14 KER31006.1 - 0.82 9.4 16.7 0.47 10.2 5.8 2.4 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PHM7_cyt PF14703.6 KER31006.1 - 0.86 9.8 9.7 3.9 7.7 6.3 2.8 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cob_adeno_trans PF01923.18 KER31006.1 - 1 9.5 7.2 4.4 7.4 2.9 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase SOGA PF11365.8 KER31006.1 - 1 10.5 18.3 8.3 7.6 5.8 3.2 1 1 2 3 3 3 0 Protein SOGA Baculo_PEP_C PF04513.12 KER31006.1 - 1.1 9.4 8.6 6.7 6.8 1.1 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 KER31006.1 - 1.1 9.2 6.3 7.4 6.5 0.2 3.5 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Fungal_TACC PF12709.7 KER31006.1 - 1.2 9.7 14.7 16 6.0 0.4 4.1 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins HAUS-augmin3 PF14932.6 KER31006.1 - 1.3 8.6 19.3 0.32 10.5 9.6 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Bacillus_HBL PF05791.11 KER31006.1 - 1.3 8.8 6.3 16 5.3 1.5 2.8 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.8 KER31006.1 - 1.4 8.9 22.2 0.19 11.8 3.1 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KER31006.1 - 1.4 8.1 13.1 1.7 7.8 4.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF5595 PF18077.1 KER31006.1 - 1.5 9.0 14.9 1.3 9.1 2.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF5595) Snf7 PF03357.21 KER31006.1 - 1.5 8.4 14.1 0.47 10.0 1.1 2.4 2 0 0 2 2 2 0 Snf7 CENP-H PF05837.12 KER31006.1 - 1.6 9.2 19.5 0.53 10.7 2.3 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) YlqD PF11068.8 KER31006.1 - 1.6 9.1 15.4 1.6 9.1 1.1 2.8 2 1 1 3 3 3 0 YlqD protein DUF4140 PF13600.6 KER31006.1 - 1.9 9.0 15.8 3 8.3 2.9 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) PI3K_P85_iSH2 PF16454.5 KER31006.1 - 2.2 7.9 21.6 6.4 6.4 4.4 3.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MCC-bdg_PDZ PF10506.9 KER31006.1 - 2.2 8.3 13.9 0.84 9.7 0.9 3.7 4 0 0 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Swi5 PF07061.11 KER31006.1 - 2.6 8.2 14.7 9.6 6.4 5.3 3.8 2 2 1 3 3 3 0 Swi5 Nas2_N PF18265.1 KER31006.1 - 2.6 8.0 10.8 20 5.2 4.0 3.9 3 1 0 3 3 3 0 Nas2 N_terminal domain Nnf1 PF03980.14 KER31006.1 - 2.7 8.4 16.9 0.5 10.8 2.5 3.5 3 1 0 3 3 3 0 Nnf1 TMF_TATA_bd PF12325.8 KER31006.1 - 2.9 8.1 24.9 3.6 7.9 5.2 3.5 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KER31006.1 - 4.2 7.4 24.5 2.9 8.0 3.7 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SpmSyn_N PF17950.1 KER31006.1 - 4.3 7.6 6.8 7.4 6.8 0.2 3.4 3 1 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal FlaC_arch PF05377.11 KER31006.1 - 4.5 7.7 17.4 3.4 8.1 1.1 4.4 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) Suppressor_APC PF11414.8 KER31006.1 - 4.9 7.3 15.4 20 5.3 0.2 4.2 3 1 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Uso1_p115_C PF04871.13 KER31006.1 - 5.3 7.4 17.5 4.9 7.5 1.7 2.9 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 KER31006.1 - 6.4 7.1 22.5 2.3 8.5 3.5 4.3 2 2 2 4 4 4 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.9 KER31006.1 - 6.9 6.9 26.3 2.5 8.3 6.2 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FlxA PF14282.6 KER31006.1 - 8.7 6.4 16.6 4.2 7.4 0.3 3.5 2 1 1 3 3 3 0 FlxA-like protein Spc7 PF08317.11 KER31007.1 - 3e-07 29.7 159.2 0.0011 17.9 29.8 7.4 1 1 6 7 7 7 5 Spc7 kinetochore protein GAS PF13851.6 KER31007.1 - 3.9e-06 26.4 164.0 0.0015 17.9 13.4 10.4 1 1 9 10 10 10 5 Growth-arrest specific micro-tubule binding ERM PF00769.19 KER31007.1 - 5.8e-05 23.0 192.1 0.0049 16.7 27.4 7.5 1 1 4 6 6 6 3 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 KER31007.1 - 0.00023 21.4 21.3 0.00023 21.4 21.3 11.5 2 2 12 14 14 11 4 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 KER31007.1 - 0.00052 19.6 185.8 0.0097 15.5 29.6 7.3 1 1 5 7 7 7 4 Mechanosensitive ion channel porin domain Allexi_40kDa PF05549.11 KER31007.1 - 0.00079 19.0 7.2 0.00079 19.0 7.2 7.3 3 3 5 8 8 8 2 Allexivirus 40kDa protein APG6_N PF17675.1 KER31007.1 - 0.00094 19.7 193.8 0.026 15.0 19.7 9.7 1 1 7 9 9 9 4 Apg6 coiled-coil region DUF745 PF05335.13 KER31007.1 - 0.0045 16.7 7.7 0.0045 16.7 7.7 8.3 2 2 5 8 8 8 3 Protein of unknown function (DUF745) HMMR_N PF15905.5 KER31007.1 - 0.0074 15.8 30.4 0.0074 15.8 30.4 6.2 1 1 5 7 7 7 2 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 KER31007.1 - 0.011 15.7 88.4 0.39 10.8 2.9 9.8 2 1 8 11 11 11 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KER31007.1 - 0.014 15.7 189.5 0.64 10.2 10.8 9.4 1 1 9 10 10 10 0 Autophagy protein 16 (ATG16) BORCS7 PF16088.5 KER31007.1 - 0.017 15.4 4.2 0.017 15.4 4.2 7.2 4 3 3 7 7 6 0 BLOC-1-related complex sub-unit 7 PRKG1_interact PF15898.5 KER31007.1 - 0.018 15.9 8.9 0.018 15.9 8.9 12.3 2 1 10 12 12 10 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 KER31007.1 - 0.089 12.8 175.2 0.02 14.9 11.9 10.4 1 1 10 11 11 11 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KER31007.1 - 0.099 10.8 123.8 0.13 10.4 5.8 6.3 1 1 5 6 6 6 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 KER31007.1 - 0.19 12.2 165.4 0.18 12.2 29.5 7.7 1 1 8 9 9 8 0 Fez1 DUF4201 PF13870.6 KER31007.1 - 0.51 10.0 148.3 0.014 15.1 9.0 10.4 2 2 7 9 9 6 0 Domain of unknown function (DUF4201) Fungal_TACC PF12709.7 KER31007.1 - 0.69 10.4 0.0 0.69 10.4 0.0 13.0 5 4 5 13 13 12 0 Fungal Transforming acidic coiled-coil (TACC) proteins IFT57 PF10498.9 KER31007.1 - 6.6 5.6 126.9 0.8 8.6 10.3 6.6 1 1 6 7 7 7 0 Intra-flagellar transport protein 57 RNA_pol_Rpb2_6 PF00562.28 KER31008.1 - 9e-95 318.0 0.0 1e-93 314.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KER31008.1 - 3.5e-23 81.6 0.0 8.3e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KER31008.1 - 2.1e-19 69.9 0.0 2.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.12 KER31008.1 - 3.7e-18 65.3 0.0 7.2e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KER31008.1 - 7.1e-14 52.0 0.2 5.9e-10 39.4 0.1 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Lactococcin_972 PF09683.10 KER31008.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) Aminotran_1_2 PF00155.21 KER31010.1 - 5.5e-71 239.6 0.0 6.6e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KER31010.1 - 4.9e-05 22.4 0.0 9.6e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KER31010.1 - 5.6e-05 22.6 0.5 9.2e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KER31010.1 - 0.05 12.1 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Atg8 PF02991.16 KER31010.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like WD40 PF00400.32 KER31011.1 - 7.5e-34 115.2 3.6 4.3e-06 27.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat CSTF1_dimer PF16699.5 KER31011.1 - 7.5e-21 73.7 0.9 7.7e-19 67.2 0.9 2.4 1 1 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain ANAPC4_WD40 PF12894.7 KER31011.1 - 1.2e-17 63.9 0.0 0.00025 21.3 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER31011.1 - 2.9e-09 37.1 0.0 1e-07 32.0 0.0 3.0 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KER31011.1 - 6.4e-06 25.4 1.5 0.00063 18.8 0.1 3.1 2 2 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KER31011.1 - 0.0022 16.4 0.1 0.0054 15.1 0.0 1.6 1 1 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 KER31011.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 KER31011.1 - 0.086 12.2 0.0 2.9 7.1 0.0 3.0 4 0 0 4 4 4 0 WD40-like domain DUF4218 PF13960.6 KER31013.1 - 0.0059 16.2 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2905 PF11146.8 KER31013.1 - 0.27 11.5 0.9 7.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) V-ATPase_G PF03179.15 KER31014.1 - 5e-18 65.6 7.5 5.8e-18 65.3 7.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit GA-like PF17573.2 KER31014.1 - 0.038 13.9 1.4 0.53 10.3 0.3 2.5 2 0 0 2 2 2 0 GA-like domain GA PF01468.17 KER31014.1 - 0.16 12.3 2.7 3.7 7.9 0.4 2.5 2 0 0 2 2 2 0 GA module UCH PF00443.29 KER31015.1 - 5.4e-26 91.6 0.0 1.3e-25 90.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER31015.1 - 1.8e-07 31.1 0.6 3.9e-06 26.7 0.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PP2C PF00481.21 KER31017.1 - 1.6e-76 257.4 0.0 2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 KER31017.1 - 7.7e-08 32.7 0.1 1.5e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 KER31017.1 - 3.2e-05 23.7 0.0 5.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C HJURP_C PF12347.8 KER31017.1 - 0.085 12.9 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF4312 PF14189.6 KER31019.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) fn3 PF00041.21 KER31022.1 - 0.00079 19.7 0.1 0.0051 17.1 0.0 2.2 2 1 0 2 2 2 1 Fibronectin type III domain Rad9 PF04139.13 KER31023.1 - 7.9e-62 208.9 1.9 1.1e-61 208.5 1.9 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KER31023.1 - 0.057 12.5 2.7 0.069 12.2 1.3 1.9 2 1 0 2 2 2 0 Repair protein Rad1/Rec1/Rad17 RasGAP PF00616.19 KER31024.1 - 1.4e-18 67.3 0.0 3.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KER31024.1 - 3.7e-05 24.0 0.0 0.00026 21.2 0.0 2.4 1 1 0 1 1 1 1 C2 domain DUF4140 PF13600.6 KER31024.1 - 0.011 16.2 1.9 4.9 7.6 0.2 3.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Peptidase_S30 PF01577.16 KER31024.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.2 3 0 0 3 3 3 0 Potyvirus P1 protease Val_tRNA-synt_C PF10458.9 KER31024.1 - 0.37 11.1 5.0 7.2 7.0 0.8 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm YabA PF06156.13 KER31024.1 - 0.58 10.8 2.1 4.7 7.9 0.1 2.9 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KER31024.1 - 1.6 8.0 4.9 4 6.7 4.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KER31025.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7TM_GPCR_Srw PF10324.9 KER31028.1 - 0.22 10.8 9.9 0.73 9.0 0.2 3.1 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw PNMA PF14893.6 KER31029.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 PNMA Arc_C PF18162.1 KER31029.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Arc C-lobe TruD PF01142.18 KER31032.1 - 1.2e-39 136.3 0.0 2e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) DEAD PF00270.29 KER31035.1 - 6.6e-48 162.8 0.0 1.6e-47 161.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER31035.1 - 2.4e-29 101.9 0.1 8e-29 100.2 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER31035.1 - 0.002 18.2 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RT_RNaseH PF17917.1 KER31036.1 - 3.8e-08 33.6 0.6 9.2e-08 32.3 0.1 1.9 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER31036.1 - 0.0036 17.3 0.5 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-met PF12874.7 KER31038.1 - 9e-11 41.8 1.2 0.015 15.7 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-U1 PF06220.12 KER31038.1 - 8.3e-08 31.9 1.9 0.0017 18.1 0.9 3.3 3 0 0 3 3 3 2 U1 zinc finger zf-C2H2_jaz PF12171.8 KER31038.1 - 1.1e-07 32.0 6.6 0.14 12.5 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KER31038.1 - 1.8e-07 31.9 0.2 4.5e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 KER31038.1 - 1.8e-07 31.4 6.6 0.27 11.6 1.2 4.2 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KER31038.1 - 0.00028 21.5 5.7 0.26 12.3 0.1 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-DBF PF07535.12 KER31038.1 - 0.0025 17.9 13.5 2.8 8.1 0.2 4.6 4 0 0 4 4 4 2 DBF zinc finger zf-C2H2 PF00096.26 KER31038.1 - 0.003 17.9 6.0 0.49 10.9 0.1 4.4 4 0 0 4 4 4 1 Zinc finger, C2H2 type Yippee-Mis18 PF03226.14 KER31038.1 - 0.0045 17.2 0.2 2 8.7 0.0 3.2 3 0 0 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.14 KER31038.1 - 0.006 16.9 2.3 0.29 11.5 0.0 3.4 2 1 2 4 4 4 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_8 PF15909.5 KER31038.1 - 0.0079 16.5 4.1 0.015 15.6 0.1 3.2 4 0 0 4 4 4 1 C2H2-type zinc ribbon AKAP95 PF04988.12 KER31038.1 - 0.039 14.2 1.7 8.8 6.5 0.3 2.8 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) RIG-I_C-RD PF11648.8 KER31038.1 - 0.1 12.8 0.6 0.54 10.5 0.0 2.3 3 0 0 3 3 3 0 C-terminal domain of RIG-I DZR PF12773.7 KER31038.1 - 0.78 9.8 12.9 4.7 7.3 0.5 4.2 3 1 0 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KER31038.1 - 2.4 8.2 11.7 2.4 8.2 0.3 4.4 5 0 0 5 5 5 0 zinc-ribbons Endonuclease_7 PF02945.15 KER31038.1 - 3.1 7.8 6.8 0.6 10.1 0.6 2.8 3 1 0 3 3 3 0 Recombination endonuclease VII Cir_N PF10197.9 KER31039.1 - 1.3e-11 44.5 5.7 1.3e-11 44.5 5.7 2.8 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 KER31039.1 - 0.0012 18.7 0.1 0.0029 17.4 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle TPR_2 PF07719.17 KER31040.1 - 1.7e-22 77.7 20.0 0.0005 20.0 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 KER31040.1 - 5.5e-16 57.6 16.9 0.003 17.3 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KER31040.1 - 8.1e-16 58.1 21.5 1.1e-05 25.6 3.6 5.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER31040.1 - 5.4e-10 38.7 12.4 0.073 13.3 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER31040.1 - 4.8e-08 33.5 11.1 0.00022 21.8 0.0 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KER31040.1 - 9.3e-08 31.6 7.9 0.061 13.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER31040.1 - 1.3e-07 31.2 1.9 0.12 12.1 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_MalT PF17874.1 KER31040.1 - 4.1e-06 26.4 5.2 0.001 18.5 3.7 3.2 2 1 1 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 KER31040.1 - 1.8e-05 24.8 0.3 0.68 10.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KER31040.1 - 6.3e-05 23.1 2.1 0.0041 17.2 0.0 3.9 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER31040.1 - 0.0006 20.3 9.6 0.32 11.6 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KER31040.1 - 0.00069 20.1 10.6 34 5.4 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31040.1 - 0.0014 18.8 14.8 0.017 15.4 0.1 5.4 3 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TIR PF01582.20 KER31040.1 - 0.029 14.2 2.2 0.059 13.2 2.2 1.5 1 0 0 1 1 1 0 TIR domain TPR_14 PF13428.6 KER31040.1 - 0.039 14.8 11.3 0.22 12.4 0.1 6.0 4 2 4 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 KER31040.1 - 0.055 13.2 2.3 0.1 12.3 0.3 2.5 2 2 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KER31040.1 - 0.16 11.8 13.7 7.8 6.5 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat OTU PF02338.19 KER31041.1 - 4.5e-14 53.0 0.2 3.6e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KER31041.1 - 0.00079 18.9 3.7 0.21 11.0 0.6 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain PWI PF01480.17 KER31042.1 - 6.7e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KER31042.1 - 6.3e-05 22.8 7.2 0.00012 21.9 7.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KER31042.1 - 0.00074 19.3 0.0 0.0095 15.7 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KER31042.1 - 0.075 13.1 5.5 0.14 12.3 5.5 1.5 1 0 0 1 1 1 0 Zinc finger domain LUC7 PF03194.15 KER31042.1 - 0.33 10.6 3.0 0.65 9.6 3.0 1.5 1 0 0 1 1 1 0 LUC7 N_terminus zf-CCCH_2 PF14608.6 KER31042.1 - 1.4 9.5 7.0 2.8 8.5 7.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Lung_7-TM_R PF06814.13 KER31043.1 - 2.4e-60 204.3 24.1 2.8e-54 184.4 16.9 2.9 1 1 1 2 2 2 2 Lung seven transmembrane receptor RVT_1 PF00078.27 KER31043.1 - 0.00054 19.5 0.0 0.0024 17.4 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GpcrRhopsn4 PF10192.9 KER31043.1 - 0.00082 18.9 20.4 0.0094 15.4 15.1 2.4 1 1 1 2 2 2 2 Rhodopsin-like GPCR transmembrane domain SCP2 PF02036.17 KER31043.1 - 0.019 15.5 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family Collagen PF01391.18 KER31045.1 - 1.4e-200 649.3 791.8 4.4e-09 36.0 24.8 30.6 6 5 21 27 27 27 24 Collagen triple helix repeat (20 copies) C4 PF01413.19 KER31045.1 - 2e-68 227.8 5.6 1.2e-35 122.2 1.6 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 KER31046.1 - 0 1334.8 1781.9 2e-09 37.1 28.1 66.1 15 13 46 61 61 61 58 Collagen triple helix repeat (20 copies) C4 PF01413.19 KER31046.1 - 9.2e-96 315.8 5.9 7.9e-33 113.2 0.8 4.2 4 0 0 4 4 4 4 C-terminal tandem repeated domain in type 4 procollagen Spy1 PF11357.8 KER31048.1 - 1.3e-51 174.3 4.3 2.2e-51 173.6 4.3 1.3 1 0 0 1 1 1 1 Cell cycle regulatory protein CNOT1_HEAT PF16418.5 KER31048.1 - 0.035 14.2 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Spectrin PF00435.21 KER31049.1 - 0 1264.2 232.3 1.9e-27 95.8 1.0 22.4 23 0 0 23 23 22 21 Spectrin repeat EFhand_Ca_insen PF08726.10 KER31049.1 - 4.7e-22 77.9 5.2 1.4e-20 73.1 2.9 4.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SH3_1 PF00018.28 KER31049.1 - 3.5e-14 52.1 1.2 5.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain EF-hand_1 PF00036.32 KER31049.1 - 1.8e-13 49.0 4.6 1.9e-06 27.0 0.2 4.1 4 0 0 4 4 4 2 EF hand SH3_9 PF14604.6 KER31049.1 - 3.3e-11 42.9 0.0 9.1e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_7 PF13499.6 KER31049.1 - 3.4e-10 40.2 1.2 3.4e-10 40.2 1.2 4.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KER31049.1 - 9.6e-10 37.6 4.5 3.4e-05 23.4 0.2 4.8 4 0 0 4 4 3 2 EF-hand domain EF-hand_8 PF13833.6 KER31049.1 - 3.1e-08 33.3 2.3 0.0014 18.5 0.2 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER31049.1 - 3.7e-08 32.5 0.7 0.027 14.0 0.0 4.3 4 0 0 4 4 4 2 EF hand SH3_2 PF07653.17 KER31049.1 - 2.6e-05 23.8 0.0 6.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KER31049.1 - 0.011 15.8 1.6 0.071 13.2 0.0 3.1 2 1 0 2 2 2 0 SH3 domain zf-MIZ PF02891.20 KER31049.1 - 0.023 14.4 3.4 0.39 10.5 0.1 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PPV_E2_N PF00508.17 KER31049.1 - 0.12 11.7 6.2 1.8 7.8 0.4 2.8 2 0 0 2 2 2 0 E2 (early) protein, N terminal INCENP_N PF12178.8 KER31049.1 - 2 8.5 7.0 0.56 10.2 0.1 4.0 4 0 0 4 4 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal Rootletin PF15035.6 KER31050.1 - 1.3e-52 178.6 24.6 1.3e-52 178.6 24.6 15.6 6 2 9 15 15 15 2 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.6 KER31050.1 - 0.0017 18.1 11.0 0.0017 18.1 11.0 18.7 5 3 10 17 17 17 6 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 KER31050.1 - 0.0026 17.8 19.0 0.0026 17.8 19.0 19.1 4 3 16 20 20 20 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_35 PF13693.6 KER31050.1 - 0.041 13.9 0.1 0.3 11.1 0.1 2.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PP2C PF00481.21 KER31051.1 - 2.1e-35 122.6 0.0 1.6e-34 119.7 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DNApol_Exo PF18136.1 KER31053.1 - 4.7e-90 301.5 0.7 1.3e-89 300.1 0.0 2.0 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KER31053.1 - 1.5e-37 129.5 0.0 2.5e-36 125.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase family A RVT_1 PF00078.27 KER31053.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KER31053.1 - 0.0071 16.2 0.0 0.046 13.6 0.0 2.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GIY-YIG PF01541.24 KER31053.1 - 0.016 15.5 0.0 0.089 13.1 0.0 2.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain DNA_pol_A_exo1 PF01612.20 KER31053.1 - 0.072 12.8 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease MENTAL PF10457.9 KER31056.1 - 0.0075 16.1 0.9 0.012 15.5 0.9 1.3 1 0 0 1 1 1 1 Cholesterol-capturing domain Ac76 PF05814.11 KER31056.1 - 0.1 12.6 0.7 0.2 11.7 0.7 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) HEAT_2 PF13646.6 KER31057.1 - 7.7e-10 39.0 11.8 2.1e-05 24.8 0.3 4.2 3 0 0 3 3 3 3 HEAT repeats Cnd1 PF12717.7 KER31057.1 - 3.2e-09 37.0 2.1 0.045 13.8 0.0 4.6 4 0 0 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KER31057.1 - 5.5e-07 29.3 19.6 0.31 11.4 0.2 7.8 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.20 KER31057.1 - 0.015 13.8 1.6 7.1 5.1 0.0 3.2 3 0 0 3 3 3 0 Adaptin N terminal region RasGEF_N_2 PF14663.6 KER31057.1 - 0.046 14.1 0.7 13 6.3 0.1 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 KER31057.1 - 1.3 9.6 13.3 1.6 9.3 0.1 5.4 6 1 0 6 6 6 0 HEAT-like repeat Sua5_yciO_yrdC PF01300.18 KER31058.1 - 1.7e-39 135.2 0.0 2.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination ORC3_N PF07034.11 KER31061.1 - 1.6e-32 112.9 0.0 3.6e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KER31061.1 - 9.6e-21 74.3 0.1 3.2e-10 40.2 0.0 3.0 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal HSP20 PF00011.21 KER31061.1 - 2.1e-06 27.8 0.0 0.00032 20.8 0.0 2.5 2 0 0 2 2 2 1 Hsp20/alpha crystallin family MliC PF09864.9 KER31061.1 - 0.041 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme SARAF PF06682.12 KER31062.1 - 2.8e-56 191.6 0.0 4.6e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2076 PF09849.9 KER31062.1 - 0.00063 19.9 0.0 0.00096 19.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CCSMST1 PF15013.6 KER31062.1 - 0.089 13.0 0.2 0.84 9.8 0.1 2.5 3 0 0 3 3 3 0 CCSMST1 family zf-HC5HC2H PF13771.6 KER31063.1 - 2.1e-10 40.7 6.8 5.3e-10 39.4 6.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KER31063.1 - 7.4e-08 32.5 3.0 7.4e-08 32.5 3.0 2.2 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 KER31063.1 - 8.8 6.3 14.7 13 5.8 9.4 3.2 3 0 0 3 3 3 0 PHD-finger Med9 PF07544.13 KER31066.1 - 3.1 8.0 5.0 8.2 6.6 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 tRNA-synt_1c PF00749.21 KER31067.1 - 5e-106 354.1 0.0 5e-106 354.1 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KER31067.1 - 2.9e-31 108.7 0.0 1.3e-30 106.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 KER31067.1 - 2.5e-17 62.8 0.2 6.5e-17 61.5 0.2 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KER31067.1 - 1.6e-16 60.8 0.0 4.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KER31067.1 - 2.3e-13 50.1 0.0 6.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_1e PF01406.19 KER31067.1 - 0.012 14.9 0.0 0.039 13.3 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Med3 PF11593.8 KER31067.1 - 0.15 11.2 17.7 0.24 10.6 17.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Presenilin PF01080.17 KER31067.1 - 0.22 10.3 12.0 0.31 9.7 12.0 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 KER31067.1 - 0.23 11.6 3.5 0.58 10.3 3.5 1.6 1 0 0 1 1 1 0 DDHD domain Suf PF05843.14 KER31067.1 - 1.7 8.6 11.0 2.7 7.9 11.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.8 KER31067.1 - 1.8 7.6 20.4 2.9 7.0 20.4 1.2 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.12 KER31067.1 - 2.7 7.8 17.1 4.9 6.9 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KER31067.1 - 4.6 5.4 10.5 6.8 4.8 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt20 PF12090.8 KER31067.1 - 4.9 6.7 14.0 9.9 5.7 14.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF4551 PF15087.6 KER31067.1 - 7.3 5.3 10.5 11 4.7 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DDRGK PF09756.9 KER31067.1 - 7.6 6.1 21.4 14 5.2 21.4 1.4 1 0 0 1 1 1 0 DDRGK domain FGGY_N PF00370.21 KER31068.1 - 1.4e-67 227.8 0.2 2.1e-67 227.3 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KER31068.1 - 2.2e-40 138.5 1.9 4.1e-40 137.6 1.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain EF_assoc_2 PF08356.12 KER31070.1 - 8.7e-34 115.4 0.0 3.7e-33 113.4 0.0 2.1 3 0 0 3 3 2 1 EF hand associated RVT_1 PF00078.27 KER31070.1 - 3.3e-29 102.0 0.0 8.1e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.22 KER31070.1 - 1.4e-16 60.6 0.0 2.8e-12 46.5 0.0 3.1 3 0 0 3 3 3 2 Ras family EF_assoc_1 PF08355.12 KER31070.1 - 7.7e-14 51.1 0.0 2.5e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.6 KER31070.1 - 4.3e-12 46.3 0.0 0.00017 22.0 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KER31070.1 - 3.3e-09 35.6 0.1 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER31070.1 - 5.9e-09 35.2 0.1 0.0061 16.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KER31070.1 - 9.6e-07 28.0 0.0 0.02 14.4 0.0 2.5 2 0 0 2 2 2 2 EF hand Roc PF08477.13 KER31070.1 - 1.3e-06 28.6 0.0 0.00014 22.1 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase zf-C2H2 PF00096.26 KER31070.1 - 0.00032 21.0 11.8 0.044 14.2 4.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type SPARC_Ca_bdg PF10591.9 KER31070.1 - 0.0014 19.0 0.0 2.2 8.6 0.0 2.6 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KER31070.1 - 0.0081 16.0 0.1 4 7.4 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KER31070.1 - 0.016 15.0 0.3 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 EF hand Hjc PF01870.18 KER31070.1 - 0.022 14.7 0.7 0.044 13.8 0.1 1.8 2 0 0 2 2 1 0 Archaeal holliday junction resolvase (hjc) AAA_14 PF13173.6 KER31070.1 - 0.061 13.4 0.4 9.3 6.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.6 KER31070.1 - 0.35 11.8 11.5 7.6 7.7 0.5 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger KH_6 PF15985.5 KER31072.1 - 4e-09 36.7 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KER31072.1 - 0.0038 17.0 0.6 0.018 14.8 0.6 2.1 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region UPF0506 PF11703.8 KER31073.1 - 1.9e-26 92.2 41.4 2.6e-13 50.1 14.1 2.0 2 0 0 2 2 2 2 UPF0506 Conotoxin_I2 PF17557.2 KER31073.1 - 1.1 9.5 41.9 0.3 11.2 9.3 4.4 3 1 1 4 4 4 0 I2-superfamily conotoxins PhoLip_ATPase_C PF16212.5 KER31075.1 - 6.7e-39 134.1 38.3 1.3e-30 107.0 20.2 3.6 4 0 0 4 4 4 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KER31075.1 - 4.3e-15 56.6 0.8 5.2e-07 30.2 1.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KER31075.1 - 1.4e-13 50.8 0.0 1e-12 48.0 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KER31075.1 - 3.1e-09 36.8 0.0 2.8e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) RVT_1 PF00078.27 KER31075.1 - 4.2e-08 33.0 0.0 7.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoLip_ATPase_N PF16209.5 KER31075.1 - 0.00013 21.6 1.7 0.0003 20.4 1.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase_3 PF08282.12 KER31075.1 - 0.0085 15.9 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cyt_b-c1_8 PF10890.8 KER31076.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 HMG_box PF00505.19 KER31077.1 - 3.1e-19 69.2 3.4 6.2e-19 68.2 3.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER31077.1 - 4.8e-09 36.7 2.3 1.2e-08 35.5 2.3 1.7 1 0 0 1 1 1 1 HMG-box domain zf-H2C2_5 PF13909.6 KER31078.1 - 2.5e-08 33.5 52.9 7.1e-07 28.9 0.6 8.1 9 0 0 9 9 9 4 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KER31078.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 9.9 12 0 0 12 12 12 1 Zinc-finger double domain Sina PF03145.16 KER31078.1 - 0.1 12.6 0.1 0.1 12.6 0.1 4.2 3 1 1 4 4 4 0 Seven in absentia protein family zf-C2H2_3rep PF18868.1 KER31078.1 - 0.26 12.0 20.0 2.7 8.7 1.2 6.0 5 1 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats AKAP95 PF04988.12 KER31078.1 - 1.4 9.1 27.3 0.1 12.8 0.4 5.9 6 0 0 6 6 6 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KER31078.1 - 7 7.8 76.9 0.21 12.5 1.5 9.7 9 0 0 9 9 9 0 C2H2-type zinc finger COX7C PF02935.16 KER31079.1 - 0.1 12.8 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Frizzled PF01534.17 KER31080.1 - 2e-56 191.4 12.6 2.6e-26 92.4 5.1 3.3 3 0 0 3 3 3 3 Frizzled/Smoothened family membrane region Fz PF01392.22 KER31080.1 - 3.2e-25 88.9 2.4 3.2e-25 88.9 2.4 2.9 3 0 0 3 3 3 1 Fz domain RhoGAP PF00620.27 KER31082.1 - 3.4e-33 114.6 0.0 1e-32 113.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RA PF00788.23 KER31082.1 - 0.0058 17.2 0.1 0.019 15.6 0.1 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.20 KER31083.1 - 0.058 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin Lipoprotein_7 PF01540.16 KER31087.1 - 0.0031 16.9 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein BLOC1_2 PF10046.9 KER31087.1 - 0.037 14.3 2.7 0.075 13.3 2.7 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 KER31087.1 - 0.04 14.1 2.0 0.076 13.3 2.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YscO PF07321.12 KER31087.1 - 0.063 13.2 7.6 0.1 12.6 7.6 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO STAT_alpha PF01017.20 KER31087.1 - 0.14 12.1 5.6 1.5 8.7 3.3 2.4 1 1 1 2 2 2 0 STAT protein, all-alpha domain HAP1_N PF04849.13 KER31087.1 - 0.23 10.6 13.1 0.77 8.9 13.1 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Spc24 PF08286.11 KER31087.1 - 0.5 10.6 2.8 3.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KER31087.1 - 0.52 10.1 2.2 0.82 9.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF5595 PF18077.1 KER31087.1 - 0.99 9.5 4.6 0.17 11.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) SlyX PF04102.12 KER31087.1 - 1 10.0 6.6 0.48 11.1 0.3 2.7 2 0 0 2 2 2 0 SlyX Csm1_N PF18504.1 KER31087.1 - 1.2 9.6 9.1 1.3 9.4 1.1 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain AAA_9 PF12781.7 KER31087.1 - 1.2 8.2 4.0 2.8 7.0 3.7 1.7 1 1 0 1 1 1 0 ATP-binding dynein motor region FUSC PF04632.12 KER31087.1 - 1.3 7.5 3.3 1.7 7.1 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 KER31087.1 - 3.7 8.0 10.4 2.9 8.3 6.3 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RRM_1 PF00076.22 KER31089.1 - 3e-23 81.4 0.1 3.6e-15 55.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER31089.1 - 0.0023 17.5 0.1 0.25 10.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER31089.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Arf PF00025.21 KER31091.1 - 2.1e-63 212.9 0.0 2.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KER31091.1 - 4.5e-10 39.8 0.0 9.6e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KER31091.1 - 1.3e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KER31091.1 - 2.2e-09 37.1 0.0 3.1e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KER31091.1 - 2.3e-08 34.1 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KER31091.1 - 4.7e-08 32.6 0.1 1.1e-05 24.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit cobW PF02492.19 KER31091.1 - 0.00019 21.0 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KER31091.1 - 0.0014 18.2 0.1 0.05 13.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER31091.1 - 0.0024 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KER31091.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PPK2 PF03976.14 KER31091.1 - 0.22 11.0 0.0 0.51 9.8 0.0 1.5 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PI3_PI4_kinase PF00454.27 KER31094.1 - 1.7e-43 149.3 0.4 8.1e-42 143.7 0.4 3.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KER31094.1 - 4e-17 62.2 0.3 3e-16 59.4 0.3 2.0 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 KER31094.1 - 5.2e-13 49.2 0.0 2e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain PI3K_C2 PF00792.24 KER31094.1 - 5.2e-10 39.4 0.0 5.7e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 KER31094.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 KER31094.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) VHS PF00790.19 KER31095.1 - 0.017 14.9 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 VHS domain FANC_SAP PF18081.1 KER31095.1 - 0.048 13.8 0.5 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Pkinase PF00069.25 KER31096.1 - 1.6e-65 221.1 0.0 9.1e-65 218.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31096.1 - 1.8e-31 109.4 0.0 3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER31096.1 - 0.00014 21.3 0.0 0.00064 19.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER31096.1 - 0.0023 16.8 0.0 0.0066 15.3 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KER31096.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KER31096.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Strep_pep PF14404.6 KER31096.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species DCX PF03607.17 KER31098.1 - 4e-17 62.1 0.0 6.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Doublecortin SAYSvFN PF10260.9 KER31099.1 - 0.006 16.5 1.3 0.006 16.5 1.3 2.1 2 0 0 2 2 2 1 Uncharacterized conserved domain (SAYSvFN) MENTAL PF10457.9 KER31099.1 - 1.8 8.3 11.2 0.41 10.4 0.5 2.4 2 1 0 2 2 2 0 Cholesterol-capturing domain Pkinase PF00069.25 KER31100.1 - 6.1e-53 179.9 0.0 8.7e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31100.1 - 1.7e-17 63.6 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER31100.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KER31100.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER31100.1 - 0.029 13.2 0.9 0.054 12.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KER31100.1 - 0.052 13.5 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KER31100.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KER31100.1 - 0.2 10.6 1.3 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain PBP1_TM PF14812.6 KER31101.1 - 0.0014 18.9 0.9 0.0014 18.9 0.9 1.8 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KER31101.1 - 0.033 14.6 3.1 0.062 13.7 3.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Acetyltransf_9 PF13527.7 KER31103.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 KER31105.1 - 1.7e-23 82.4 19.8 0.00013 22.7 0.1 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31105.1 - 1e-09 38.6 8.9 0.0011 19.2 0.5 4.4 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER31105.1 - 0.00022 20.3 0.0 0.0092 15.0 0.0 2.8 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallopep PF12044.8 KER31109.1 - 4.6e-52 177.1 0.0 6.4e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.24 KER31109.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 KER31109.1 - 0.036 13.0 0.6 0.064 12.2 0.6 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 KER31109.1 - 0.039 13.9 0.2 0.087 12.7 0.2 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KER31109.1 - 0.046 14.2 0.1 0.08 13.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Tat PF00539.18 KER31109.1 - 0.15 12.2 1.7 0.39 10.9 1.7 1.7 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) La PF05383.17 KER31111.1 - 3.3e-10 39.8 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 La domain RVT_1 PF00078.27 KER31111.1 - 6e-07 29.2 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol PF00940.19 KER31113.1 - 2e-152 507.9 0.0 3.1e-152 507.2 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KER31113.1 - 1.1e-20 74.3 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Spc7 PF08317.11 KER31114.1 - 7.9 5.3 12.3 0.32 9.8 0.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DnaJ PF00226.31 KER31115.1 - 1.1e-18 67.2 1.1 1.1e-18 67.1 0.1 1.5 2 0 0 2 2 2 1 DnaJ domain RCC1 PF00415.18 KER31116.1 - 1.9e-35 121.2 20.2 5.9e-07 30.0 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KER31116.1 - 8.3e-15 54.1 33.8 0.00014 21.5 0.4 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 KER31117.1 - 1.3e-40 139.5 0.1 5.3e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GCP_C_terminal PF04130.13 KER31117.1 - 1.9e-18 67.0 2.1 1.9e-18 67.0 2.1 4.0 4 0 0 4 4 4 1 Gamma tubulin complex component C-terminal Pkinase_Tyr PF07714.17 KER31117.1 - 1e-15 57.8 0.0 1.7e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER31117.1 - 1.2e-06 28.1 0.0 1.2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Rep_fac-A_3 PF08661.11 KER31117.1 - 0.15 12.4 0.7 0.42 11.0 0.7 1.7 1 0 0 1 1 1 0 Replication factor A protein 3 CENP-F_leu_zip PF10473.9 KER31117.1 - 2.2 8.3 52.3 0.5 10.4 0.6 4.4 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C2H2 PF00096.26 KER31121.1 - 2.8e-11 43.2 18.2 0.00068 20.0 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31121.1 - 2.2e-08 34.2 16.1 0.015 16.1 2.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31121.1 - 0.00046 20.5 1.6 0.00046 20.5 1.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain BolA PF01722.18 KER31121.1 - 0.015 15.5 0.5 0.056 13.7 0.5 2.0 1 0 0 1 1 1 0 BolA-like protein zf-Di19 PF05605.12 KER31121.1 - 0.031 14.6 10.1 0.47 10.8 1.6 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KER31121.1 - 0.039 13.9 12.2 0.1 12.6 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger SNAP PF14938.6 KER31121.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Activator_LAG-3 PF11498.8 KER31121.1 - 0.57 9.1 13.5 1.1 8.1 13.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-C2H2_3rep PF18868.1 KER31121.1 - 0.6 10.8 10.4 2.4 8.9 0.0 3.6 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KER31121.1 - 0.64 10.5 15.5 1.6 9.3 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KER31121.1 - 0.73 9.6 12.9 0.42 10.4 0.1 3.1 2 1 1 3 3 3 0 zinc-finger C2H2-type DUF629 PF04780.12 KER31121.1 - 7.1 5.0 10.3 12 4.3 1.8 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF629) zf-LYAR PF08790.11 KER31121.1 - 8.8 6.3 7.0 31 4.6 0.0 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DC_STAMP PF07782.13 KER31122.1 - 6.5e-35 120.7 0.9 2.2e-34 119.0 0.1 2.3 2 0 0 2 2 2 1 DC-STAMP-like protein Tetraspanin PF00335.20 KER31122.1 - 1.8e-10 40.9 0.5 1.8e-10 40.9 0.5 2.7 3 0 0 3 3 3 1 Tetraspanin family zf-C3HC4_3 PF13920.6 KER31122.1 - 0.041 13.8 3.9 0.13 12.2 3.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RasGAP_C PF03836.15 KER31122.1 - 0.7 10.0 5.3 0.95 9.6 2.6 2.7 2 0 0 2 2 2 0 RasGAP C-terminus IncD PF17628.2 KER31122.1 - 1.5 8.6 3.7 0.89 9.3 0.4 2.2 2 0 0 2 2 2 0 Inclusion membrane protein D Ig_3 PF13927.6 KER31123.1 - 7.5e-78 257.2 9.2 1.7e-13 51.0 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 KER31123.1 - 6.7e-76 250.4 0.0 1.4e-11 44.2 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 KER31123.1 - 3.7e-57 190.6 8.2 5.8e-10 39.4 0.0 6.8 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.25 KER31123.1 - 1.4e-43 147.0 0.2 1.5e-08 34.7 0.0 7.3 6 1 0 7 7 7 6 Immunoglobulin domain DC_STAMP PF07782.13 KER31123.1 - 1.5e-29 103.2 0.9 1.5e-29 103.2 0.9 2.4 3 0 0 3 3 3 1 DC-STAMP-like protein fn3 PF00041.21 KER31123.1 - 3e-24 85.2 7.3 3.3e-08 33.8 0.1 6.0 6 0 0 6 6 6 3 Fibronectin type III domain C2-set_2 PF08205.12 KER31123.1 - 8.7e-15 54.6 0.4 0.015 15.4 0.0 6.1 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain V-set PF07686.17 KER31123.1 - 1.6e-13 50.8 10.4 0.25 11.5 0.0 10.0 6 5 3 9 9 9 3 Immunoglobulin V-set domain Tetraspanin PF00335.20 KER31123.1 - 4.2e-11 43.0 4.6 1.5e-10 41.2 2.1 2.6 2 0 0 2 2 2 1 Tetraspanin family Ig_5 PF16681.5 KER31123.1 - 2.3e-05 24.7 0.2 0.94 9.9 0.0 5.8 7 0 0 7 7 7 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_6 PF18452.1 KER31123.1 - 5.1e-05 22.8 0.0 0.85 9.2 0.0 4.4 4 0 0 4 4 4 1 Immunoglobulin domain Izumo-Ig PF16706.5 KER31123.1 - 8.2e-05 22.6 0.0 0.047 13.8 0.0 3.6 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain zf-RING_2 PF13639.6 KER31123.1 - 6.6 7.2 6.3 27 5.2 6.3 2.2 1 0 0 1 1 1 0 Ring finger domain Oxidored_molyb PF00174.19 KER31124.1 - 2.2e-49 167.4 0.0 3.7e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KER31124.1 - 3.3e-33 114.6 0.0 6e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KER31124.1 - 9.8e-17 60.9 0.2 1.8e-16 60.1 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KER31124.1 - 0.063 13.3 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat SRP72 PF08492.12 KER31126.1 - 2.3e-19 69.5 5.2 2.3e-19 69.5 5.2 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KER31126.1 - 8.8e-15 54.8 2.9 2e-14 53.6 0.1 2.8 4 0 0 4 4 4 1 Putative TPR-like repeat ANAPC3 PF12895.7 KER31126.1 - 0.11 12.7 14.8 0.11 12.8 0.9 5.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER31126.1 - 0.49 11.3 20.4 14 6.9 0.1 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER31126.1 - 0.94 9.8 13.1 27 5.2 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KER31126.1 - 0.98 10.1 12.4 9.9 6.9 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 KER31129.1 - 0.029 14.4 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pro_isomerase PF00160.21 KER31130.1 - 1.4e-47 161.9 0.1 3.4e-47 160.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syja_N PF02383.18 KER31131.1 - 8e-65 219.3 0.0 1.1e-64 218.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KER31131.1 - 1.5e-15 57.4 0.5 3e-15 56.4 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KER31132.1 - 6.3e-10 38.7 18.3 6.9e-06 25.7 4.3 3.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KER31132.1 - 1.9e-07 31.3 18.6 0.0091 16.4 0.7 4.3 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER31132.1 - 0.0044 17.4 21.3 0.61 10.8 0.6 5.9 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 KER31132.1 - 1.2 9.4 0.1 1.2 9.4 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat Pkinase PF00069.25 KER31133.1 - 9.4e-24 84.2 0.0 8.3e-22 77.8 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31133.1 - 4.3e-23 81.9 0.1 4.5e-21 75.3 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KER31133.1 - 4.1e-13 48.6 0.7 4.1e-13 48.6 0.7 2.1 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KER31133.1 - 0.00028 21.9 6.0 0.00028 21.9 6.0 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.23 KER31133.1 - 0.0005 20.1 0.0 0.00097 19.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KER31133.1 - 0.0056 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KER31133.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-C2H2 PF00096.26 KER31135.1 - 4.5e-14 52.0 29.9 0.00032 21.0 4.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31135.1 - 1.2e-09 38.2 28.5 0.01 16.6 0.4 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KER31135.1 - 1.5e-05 25.2 21.9 0.064 13.7 0.6 4.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KER31135.1 - 0.00042 20.0 31.2 0.13 12.0 7.3 4.7 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KER31135.1 - 0.00054 20.3 0.2 0.00054 20.3 0.2 4.9 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KER31135.1 - 0.0011 18.9 21.2 0.029 14.4 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KER31135.1 - 0.0094 16.6 8.6 0.14 12.9 1.3 2.5 1 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KER31135.1 - 0.018 15.3 16.4 8.7 6.8 2.5 4.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KER31135.1 - 0.45 10.4 5.5 4 7.3 0.2 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 KER31135.1 - 8.6 6.1 14.1 29 4.4 1.9 4.1 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 KER31136.1 - 2e-17 62.6 27.5 0.00014 22.1 0.9 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31136.1 - 4e-16 58.3 26.9 0.00024 21.7 0.8 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31136.1 - 3.1e-12 46.3 24.6 5.6e-07 29.7 0.4 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER31136.1 - 4e-10 39.7 17.4 0.041 14.2 0.0 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER31136.1 - 8.5e-09 35.5 19.7 0.016 15.5 0.1 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KER31136.1 - 2.7e-06 27.0 25.0 0.025 14.3 3.3 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KER31136.1 - 1.2e-05 24.9 11.1 0.0089 15.8 0.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KER31136.1 - 0.00057 20.2 14.9 1.2 9.6 9.9 4.0 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KER31136.1 - 0.016 15.2 24.2 0.17 11.9 2.7 4.3 3 1 1 4 4 4 0 BED zinc finger zf-C2H2_3rep PF18868.1 KER31136.1 - 0.029 15.1 13.2 0.45 11.2 3.0 3.5 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats GAGA PF09237.11 KER31136.1 - 0.13 12.0 6.4 0.49 10.2 0.1 3.4 2 1 1 3 3 3 0 GAGA factor ARS2 PF04959.13 KER31136.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.5 2 1 1 3 3 3 0 Arsenite-resistance protein 2 zf-met2 PF12907.7 KER31136.1 - 0.33 11.1 0.2 0.33 11.1 0.2 4.2 4 0 0 4 4 4 0 Zinc-binding zf-LYAR PF08790.11 KER31136.1 - 0.49 10.3 18.4 5.3 7.0 0.7 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 KER31136.1 - 0.77 9.7 6.4 0.27 11.2 1.1 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF629 PF04780.12 KER31136.1 - 0.92 8.0 15.6 2.6 6.5 0.6 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 KER31136.1 - 0.95 9.5 22.1 5.4 7.1 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER31136.1 - 1.8 8.9 9.6 0.22 11.8 1.8 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon Zn-C2H2_12 PF18112.1 KER31136.1 - 2.7 8.5 10.1 11 6.6 0.0 4.1 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain HNH_5 PF14279.6 KER31136.1 - 7.2 6.6 13.6 26 4.8 0.5 4.0 4 0 0 4 4 4 0 HNH endonuclease AAA_22 PF13401.6 KER31138.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arrestin_N PF00339.29 KER31140.1 - 7e-33 113.7 0.1 3.6e-14 53.0 0.0 3.3 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KER31140.1 - 1e-22 81.0 1.6 1.4e-22 80.6 0.1 2.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain ADD_ATRX PF17981.1 KER31143.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain Lentivirus_VIF PF05851.11 KER31143.1 - 0.14 11.0 0.0 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) TMEM43 PF07787.12 KER31143.1 - 0.84 9.0 10.5 5.1 6.4 2.7 2.6 2 1 0 2 2 2 0 Transmembrane protein 43 RVT_1 PF00078.27 KER31144.1 - 0.00025 20.6 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KER31144.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER31144.1 - 0.014 14.9 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PEMT PF04191.13 KER31144.1 - 0.038 14.4 0.3 0.088 13.2 0.3 1.6 1 1 0 1 1 1 0 Phospholipid methyltransferase Ribosomal_L5e PF17144.4 KER31145.1 - 7.7e-86 286.1 1.3 7.7e-86 286.1 1.3 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KER31145.1 - 1.7e-33 115.4 2.0 4.1e-33 114.2 2.0 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region TPR_MLP1_2 PF07926.12 KER31146.1 - 1.5e-11 44.4 18.8 1.5e-11 44.4 18.8 15.8 9 6 5 14 14 14 8 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.12 KER31146.1 - 4.7 7.2 7.1 16 5.6 1.4 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat LIF_OSM PF01291.17 KER31146.1 - 5.4 7.1 13.3 3.5 7.8 0.3 5.3 4 1 1 5 5 5 0 LIF / OSM family VPS53_C PF16854.5 KER31146.1 - 7.6 6.4 10.1 0.69 9.8 1.8 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus Glutaredoxin PF00462.24 KER31147.1 - 8e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KER31147.1 - 0.00058 20.2 0.1 0.00082 19.7 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TPR_1 PF00515.28 KER31148.1 - 1.6e-16 59.3 19.7 0.00036 20.2 1.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KER31148.1 - 4.1e-13 48.3 21.6 0.0012 18.8 0.4 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KER31148.1 - 2.5e-10 39.7 13.6 0.024 14.9 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER31148.1 - 8.8e-09 34.9 7.3 0.15 11.7 0.9 6.7 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.6 KER31148.1 - 1.4e-08 34.9 22.4 0.0018 18.6 1.6 6.7 3 2 3 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER31148.1 - 3.2e-07 30.6 10.2 0.66 11.0 1.0 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER31148.1 - 1.9e-06 27.8 9.3 0.16 12.4 0.0 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER31148.1 - 1.6e-05 25.4 10.3 0.12 13.0 0.9 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER31148.1 - 0.00058 19.6 0.6 0.00058 19.6 0.6 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KER31148.1 - 0.0012 18.1 3.5 0.1 11.8 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF5112 PF17139.4 KER31148.1 - 0.0031 17.0 6.9 0.21 11.0 1.5 3.0 3 1 0 3 3 3 2 Domain of unknown function (DUF5112) TPR_9 PF13371.6 KER31148.1 - 0.0033 17.5 3.8 0.02 15.0 0.0 3.3 3 1 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KER31148.1 - 0.065 13.5 0.0 1.4 9.3 0.0 3.2 3 0 0 3 3 2 0 PPR repeat TPR_19 PF14559.6 KER31148.1 - 0.086 13.4 15.4 0.31 11.6 0.5 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER31148.1 - 0.16 12.0 15.9 39 4.6 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31148.1 - 0.21 11.8 13.8 2.3 8.5 3.6 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KER31148.1 - 1.8 9.4 14.1 7.8 7.4 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat SNF2_N PF00176.23 KER31149.1 - 5.5e-31 107.5 0.0 7.2e-26 90.7 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain PHD PF00628.29 KER31149.1 - 0.0046 16.8 2.4 0.014 15.2 2.4 1.8 1 0 0 1 1 1 1 PHD-finger Myb_DNA-bind_2 PF08914.11 KER31149.1 - 0.14 12.4 2.9 37 4.6 0.0 3.7 4 0 0 4 4 4 0 Rap1 Myb domain Prok-RING_1 PF14446.6 KER31149.1 - 0.19 11.7 3.4 0.38 10.7 3.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SNF2_N PF00176.23 KER31151.1 - 7.3e-44 149.9 0.0 1.2e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KER31151.1 - 7.3e-05 22.5 7.6 7.3e-05 22.5 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 KER31151.1 - 0.0018 18.1 5.6 0.0061 16.4 5.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER31151.1 - 0.0033 17.7 9.8 0.014 15.7 9.8 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KER31151.1 - 0.0071 16.1 7.2 0.012 15.4 5.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KER31151.1 - 0.0072 16.3 7.5 0.02 14.8 7.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain DUF4420 PF14390.6 KER31151.1 - 0.05 12.8 0.8 0.091 12.0 0.8 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) Prok-RING_4 PF14447.6 KER31151.1 - 0.29 11.0 7.4 1.3 8.9 7.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KER31151.1 - 0.53 10.2 10.1 2 8.4 10.1 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER31151.1 - 0.54 10.3 3.9 1.6 8.9 3.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KER31151.1 - 4.1 7.4 15.4 0.11 12.4 8.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MBOAT PF03062.19 KER31152.1 - 0.0015 18.0 9.8 0.0015 18.0 9.8 3.6 2 2 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.17 KER31154.1 - 0.0001 22.8 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SH3_9 PF14604.6 KER31156.1 - 3.2e-10 39.7 0.1 5.5e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER31156.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER31156.1 - 3.9e-06 26.4 0.0 6.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain HAP1_N PF04849.13 KER31157.1 - 0.0037 16.5 13.7 0.0037 16.5 13.7 5.6 2 1 1 5 5 5 2 HAP1 N-terminal conserved region YabA PF06156.13 KER31157.1 - 0.081 13.6 0.2 0.081 13.6 0.2 8.0 7 2 2 9 9 9 0 Initiation control protein YabA Shugoshin_N PF07558.11 KER31157.1 - 0.32 10.9 8.3 13 5.8 1.0 5.5 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.6 KER31157.1 - 0.4 10.6 3.0 60 3.6 0.9 4.1 4 0 0 4 4 4 0 Alternative WD40 repeat motif NPV_P10 PF05531.12 KER31157.1 - 1.7 9.1 24.1 2.4 8.7 0.6 6.5 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 KER31157.1 - 1.9 8.3 39.3 0.97 9.2 4.3 6.8 3 1 5 8 8 8 0 Phage minor structural protein GP20 Spc7 PF08317.11 KER31157.1 - 2.1 7.2 74.2 1.3 7.9 11.3 5.8 3 1 2 6 6 6 0 Spc7 kinetochore protein LPP PF04728.13 KER31157.1 - 3.6 8.0 31.3 12 6.4 0.1 8.6 9 1 0 9 9 9 0 Lipoprotein leucine-zipper GAS PF13851.6 KER31157.1 - 4.1 6.7 68.3 0.6 9.4 12.8 6.6 3 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding Pkinase PF00069.25 KER31158.1 - 1.5e-59 201.6 0.0 2.2e-51 174.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER31158.1 - 1e-22 80.7 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER31158.1 - 0.0023 16.9 0.0 0.0061 15.5 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER31158.1 - 0.047 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER31158.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KER31158.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KER31158.1 - 0.17 11.5 0.1 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 N6-adenineMlase PF10237.9 KER31160.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase GNT-I PF03071.15 KER31164.1 - 6.6e-111 371.1 0.0 8e-111 370.9 0.0 1.0 1 0 0 1 1 1 1 GNT-I family GNT-I PF03071.15 KER31165.1 - 4.8e-113 378.2 0.0 6.3e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 KER31165.1 - 0.0048 16.8 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2628 PF10947.8 KER31165.1 - 0.16 12.4 4.3 3.7 8.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) GTP_cyclohydroI PF01227.22 KER31166.1 - 1.8e-71 239.2 0.4 2.8e-71 238.7 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KER31166.1 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF4734 PF15881.5 KER31166.1 - 0.08 13.1 0.1 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) DUF3463 PF11946.8 KER31167.1 - 0.078 12.8 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) GTP_cyclohydroI PF01227.22 KER31168.1 - 6.3e-72 240.8 0.2 1.5e-71 239.5 0.1 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 KER31168.1 - 0.00083 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein UMP1 PF05348.11 KER31169.1 - 5.6e-14 52.4 0.0 7.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cadherin PF00028.17 KER31171.1 - 5.6e-44 148.5 6.3 9.2e-12 45.3 0.0 7.0 6 1 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 KER31171.1 - 6.5e-07 29.3 0.6 0.22 11.5 0.0 4.5 4 0 0 4 4 4 2 Cadherin-like Cadherin_2 PF08266.12 KER31171.1 - 5.6e-05 22.9 0.2 0.39 10.6 0.0 3.5 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 KER31171.1 - 0.0014 18.9 0.0 0.17 12.2 0.0 3.1 3 0 0 3 3 3 1 RET Cadherin like domain 1 SusE PF14292.6 KER31171.1 - 0.042 14.1 0.8 10 6.4 0.0 3.4 3 0 0 3 3 3 0 SusE outer membrane protein Cadherin_4 PF17803.1 KER31171.1 - 0.35 11.5 14.6 0.38 11.4 0.1 4.5 5 0 0 5 5 5 0 Bacterial cadherin-like domain Cadherin PF00028.17 KER31172.1 - 9.7e-24 83.6 0.0 2.1e-10 40.9 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 KER31172.1 - 7.7e-07 28.9 0.0 0.0003 20.6 0.0 2.7 2 0 0 2 2 2 2 Cadherin-like UCH PF00443.29 KER31173.1 - 2.5e-31 109.1 0.0 4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER31173.1 - 5.7e-17 62.3 0.8 9.2e-16 58.3 0.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNARE_assoc PF09335.11 KER31174.1 - 8.8e-16 58.5 5.9 8.8e-16 58.5 5.9 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein NHL PF01436.21 KER31176.1 - 1.2e-13 50.3 8.8 0.011 15.8 0.1 6.3 6 0 0 6 6 6 4 NHL repeat Ldl_recept_b PF00058.17 KER31176.1 - 0.044 14.3 0.4 1.6e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B SBBP PF06739.11 KER31176.1 - 0.17 11.9 0.6 3.7 7.6 0.4 3.1 3 0 0 3 3 3 0 Beta-propeller repeat DUF1192 PF06698.11 KER31177.1 - 0.0024 17.9 16.9 0.27 11.3 0.1 5.7 5 1 0 5 5 5 2 Protein of unknown function (DUF1192) DUF724 PF05266.14 KER31177.1 - 0.011 15.6 18.4 0.011 15.6 18.4 6.8 3 2 1 6 6 6 0 Protein of unknown function (DUF724) RelB PF04221.12 KER31177.1 - 0.017 15.1 0.8 16 5.6 0.1 3.9 3 0 0 3 3 3 0 RelB antitoxin HTH_37 PF13744.6 KER31177.1 - 0.022 14.7 0.2 0.022 14.7 0.2 4.4 4 0 0 4 4 4 0 Helix-turn-helix domain DUF3024 PF11225.8 KER31177.1 - 0.055 13.7 0.1 30 5.0 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Nup54_57_C PF18570.1 KER31177.1 - 2.6 7.7 18.2 4.2 7.0 0.1 5.4 5 0 0 5 5 5 0 NUP57/Nup54 C-terminal domain HSL_N PF06350.12 KER31178.1 - 9.8e-39 133.1 2.7 2e-21 76.3 0.0 3.2 3 0 0 3 3 3 3 Hormone-sensitive lipase (HSL) N-terminus Abhydrolase_3 PF07859.13 KER31178.1 - 5.4e-37 127.7 0.0 1.6e-27 96.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold RVT_1 PF00078.27 KER31178.1 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Say1_Mug180 PF10340.9 KER31178.1 - 3.1e-07 29.6 0.0 2.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Exo_endo_phos_2 PF14529.6 KER31178.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase His_Phos_1 PF00300.22 KER31179.1 - 5.7e-24 84.9 0.0 2.2e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) UQ_con PF00179.26 KER31183.1 - 1.5e-30 105.7 0.1 1.7e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER31183.1 - 0.18 11.5 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B PBP1_TM PF14812.6 KER31184.1 - 0.14 12.5 0.3 0.19 12.1 0.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF498 PF04430.14 KER31186.1 - 4.2e-14 52.5 0.0 9e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DNA_pol_A PF00476.20 KER31187.1 - 1.4e-63 215.3 0.0 7.2e-60 203.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family A DEAD PF00270.29 KER31187.1 - 1e-14 54.7 0.0 1e-13 51.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER31187.1 - 9.3e-11 42.1 0.0 8.9e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RVT_1 PF00078.27 KER31187.1 - 3e-10 40.0 0.0 7.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ResIII PF04851.15 KER31187.1 - 0.00031 20.8 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KER31187.1 - 0.17 12.5 0.0 0.91 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain Zn_Tnp_IS91 PF14319.6 KER31187.1 - 0.73 9.9 3.3 2 8.5 3.3 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain Per1 PF04080.13 KER31188.1 - 1.9e-80 270.3 15.5 2.7e-80 269.8 15.5 1.1 1 0 0 1 1 1 1 Per1-like family FYVE PF01363.21 KER31191.1 - 4.9e-14 52.2 5.9 1e-13 51.2 5.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 KER31191.1 - 5.2e-12 46.1 11.9 0.0027 18.5 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KER31191.1 - 0.0072 15.1 0.2 0.13 11.0 0.0 2.3 2 1 0 2 2 2 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KER31191.1 - 0.035 14.4 0.8 6.2 7.2 0.2 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MqsA_antitoxin PF15731.5 KER31191.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF2688 PF10892.8 KER31191.1 - 0.4 10.2 3.2 0.67 9.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) FYVE_2 PF02318.16 KER31191.1 - 1.5 9.0 5.5 4.7 7.4 5.5 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger Yip1 PF04893.17 KER31193.1 - 4.7e-08 32.9 12.1 7.1e-08 32.4 12.1 1.2 1 0 0 1 1 1 1 Yip1 domain Peptidase_S28 PF05577.12 KER31194.1 - 4.5e-49 167.4 0.0 3.1e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 RVT_1 PF00078.27 KER31194.1 - 2.2e-12 47.0 0.0 3.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_1 PF00561.20 KER31194.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KER31194.1 - 0.00049 20.8 0.0 0.008 16.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KER31194.1 - 0.0006 19.4 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KER31194.1 - 0.00085 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KER31194.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 KER31194.1 - 0.027 13.2 0.4 0.08 11.6 0.1 1.7 2 0 0 2 2 2 0 PS-10 peptidase S37 Abhydrolase_2 PF02230.16 KER31194.1 - 0.084 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SpoU_methylase PF00588.19 KER31196.1 - 3e-22 79.3 0.0 3.7e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KER31196.1 - 0.014 15.6 0.0 0.041 14.2 0.0 1.8 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding tRNA_U5-meth_tr PF05958.11 KER31197.1 - 7.2e-06 25.2 0.3 1.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Vps16_C PF04840.12 KER31198.1 - 1.5e-60 205.0 2.6 5.6e-25 88.1 0.4 4.4 3 2 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.13 KER31198.1 - 2e-42 145.4 0.0 4.1e-42 144.4 0.0 1.5 1 1 0 1 1 1 1 Vps16, N-terminal region GDP_Man_Dehyd PF16363.5 KER31199.1 - 5.2e-56 190.4 0.0 7e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KER31199.1 - 6.9e-54 182.8 0.0 9.1e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KER31199.1 - 6.4e-18 64.9 0.0 9.7e-17 61.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KER31199.1 - 6.7e-14 51.5 0.1 3.6e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KER31199.1 - 1.2e-08 34.5 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KER31199.1 - 2.4e-07 30.2 0.0 0.00046 19.4 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KER31199.1 - 3.1e-06 26.8 0.0 8e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KER31199.1 - 0.00043 20.3 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KER31199.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KER31199.1 - 0.02 14.5 0.3 2.3 7.7 0.2 2.3 2 1 0 2 2 2 0 NmrA-like family DUF4537 PF15057.6 KER31201.1 - 4.7e-10 39.5 0.0 9.8e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tetraspanin PF00335.20 KER31203.1 - 1.3e-08 34.8 11.0 1.8e-08 34.4 11.0 1.1 1 0 0 1 1 1 1 Tetraspanin family Pox_A14 PF05767.12 KER31203.1 - 5e-05 23.4 1.3 5e-05 23.4 1.3 1.8 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 DUF3681 PF12442.8 KER31203.1 - 0.091 13.2 4.6 0.16 12.5 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) Bac_export_2 PF01312.19 KER31203.1 - 0.93 8.6 3.4 1.2 8.3 0.5 1.9 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family SLATT_5 PF18160.1 KER31203.1 - 3 7.1 4.8 6 6.1 4.8 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Tetraspanin PF00335.20 KER31204.1 - 0.09 12.5 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Tetraspanin family Peptidase_M3 PF01432.20 KER31205.1 - 1.9e-98 330.7 0.0 7.8e-86 289.1 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M3 VHP PF02209.19 KER31208.1 - 2.2e-15 56.4 0.7 2.2e-15 56.4 0.7 1.9 2 0 0 2 2 2 1 Villin headpiece domain LIM PF00412.22 KER31208.1 - 4.6e-13 49.2 9.9 5.5e-07 29.7 4.7 2.4 2 0 0 2 2 2 2 LIM domain C1_1 PF00130.22 KER31208.1 - 0.073 13.0 2.7 0.24 11.3 2.7 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0029 PF01205.19 KER31210.1 - 1.7e-33 115.1 0.0 3.7e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KER31210.1 - 3.6e-13 49.8 0.0 5.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Dpy19 PF10034.9 KER31211.1 - 4.7e-39 134.2 0.5 2e-30 105.6 0.0 3.0 2 1 1 3 3 3 3 Q-cell neuroblast polarisation Rad1 PF02144.16 KER31212.1 - 1.2e-23 83.6 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 ASC PF00858.24 KER31215.1 - 8e-48 163.5 9.1 1.1e-47 163.1 9.1 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ADH_zinc_N PF00107.26 KER31219.1 - 3.7e-16 59.3 0.0 6.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KER31219.1 - 7.2e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KER31219.1 - 5.3e-06 27.5 0.0 1.4e-05 26.2 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase G_path_suppress PF15991.5 KER31220.1 - 8.6e-11 42.5 12.8 8.6e-11 42.5 12.8 3.3 3 1 0 3 3 3 1 G-protein pathway suppressor Apt1 PF10351.9 KER31220.1 - 0.16 10.8 14.0 0.2 10.4 1.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 KER31220.1 - 0.2 11.0 8.3 1.5 8.1 2.8 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Tim54 PF11711.8 KER31220.1 - 4.8 5.9 15.0 0.024 13.5 5.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ras PF00071.22 KER31222.1 - 2.5e-52 176.7 0.2 3.8e-52 176.1 0.2 1.2 1 0 0 1 1 1 1 Ras family RVT_1 PF00078.27 KER31222.1 - 5.1e-33 114.5 0.0 9.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Roc PF08477.13 KER31222.1 - 1.6e-28 99.3 0.2 2.7e-28 98.6 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER31222.1 - 2.2e-11 43.5 0.1 3.6e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER31222.1 - 0.0086 15.6 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER31222.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Macoilin PF09726.9 KER31223.1 - 0.0034 16.0 1.4 0.0043 15.7 1.4 1.3 1 0 0 1 1 1 1 Macoilin family Sas6_CC PF18594.1 KER31223.1 - 0.41 10.5 5.3 0.12 12.1 1.8 2.0 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FRG1 PF06229.12 KER31223.1 - 7 6.3 6.7 2.5 7.8 3.3 1.7 1 1 1 2 2 2 0 FRG1-like domain Cadherin PF00028.17 KER31224.1 - 7.7e-69 228.2 9.1 1e-12 48.3 0.0 11.1 7 5 2 9 9 9 9 Cadherin domain Cadherin_2 PF08266.12 KER31224.1 - 5.3e-10 39.0 1.2 0.00025 20.8 0.3 4.7 4 0 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 KER31224.1 - 0.00016 21.9 0.0 0.85 9.9 0.0 4.7 5 0 0 5 5 5 1 RET Cadherin like domain 1 Ribosomal_L27A PF00828.19 KER31227.1 - 6.9e-08 33.2 0.0 1.2e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Exo_endo_phos_2 PF14529.6 KER31227.1 - 9.2e-08 32.0 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase NAC PF01849.18 KER31229.1 - 1e-23 83.0 0.2 4.2e-23 81.1 0.1 2.0 2 0 0 2 2 2 1 NAC domain 7tm_1 PF00001.21 KER31231.1 - 2.3e-46 158.3 23.0 2.8e-46 158.0 23.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER31231.1 - 5.6e-10 39.0 20.3 8.7e-10 38.4 20.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Iso_dh PF00180.20 KER31232.1 - 4.3e-65 220.2 0.0 5e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BBL5 PF07289.11 KER31234.1 - 7.1e-31 107.5 0.0 5.3e-30 104.6 0.0 1.9 1 1 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Sigma70_r4 PF04545.16 KER31234.1 - 0.31 10.6 1.2 0.72 9.4 0.1 2.2 2 1 0 2 2 2 0 Sigma-70, region 4 BBL5 PF07289.11 KER31235.1 - 3.5e-10 39.5 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein MCM PF00493.23 KER31236.1 - 1e-98 328.9 0.0 1.4e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KER31236.1 - 2.5e-36 124.3 0.6 4.7e-36 123.4 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER31236.1 - 3e-27 94.8 0.9 6.8e-27 93.7 0.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KER31236.1 - 1e-06 28.3 0.0 0.00038 19.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KER31236.1 - 1.5e-05 25.0 0.0 3.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KER31236.1 - 0.017 15.0 0.0 0.048 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KER31236.1 - 0.036 13.8 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain MANEC PF07502.14 KER31238.1 - 1.2e-12 47.9 6.1 3.2e-12 46.5 6.1 1.8 1 0 0 1 1 1 1 MANEC domain Ldl_recept_a PF00057.18 KER31238.1 - 3.6e-06 27.1 7.5 3.6e-06 27.1 7.5 3.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A EB PF01683.18 KER31238.1 - 0.91 9.9 25.9 0.61 10.4 15.0 2.5 1 1 1 2 2 2 0 EB module Spectrin PF00435.21 KER31240.1 - 3.9e-241 782.6 157.2 6e-21 74.9 8.2 17.5 17 0 0 17 17 17 17 Spectrin repeat CH PF00307.31 KER31240.1 - 2.8e-46 156.2 3.1 5.3e-24 84.5 0.0 3.8 4 0 0 4 4 4 2 Calponin homology (CH) domain PH_9 PF15410.6 KER31240.1 - 3.6e-19 69.3 0.1 1.9e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KER31240.1 - 3.3e-13 50.0 0.0 9.6e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 KER31240.1 - 2.8e-07 30.3 0.1 0.0001 22.1 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CHASE9 PF17153.4 KER31240.1 - 0.13 12.4 1.6 1.2 9.3 0.1 2.9 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular GIT_CC PF16559.5 KER31240.1 - 8.6 6.3 10.1 2.8 7.9 1.3 4.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CH PF00307.31 KER31243.1 - 2e-28 98.8 0.0 3.6e-12 46.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER31243.1 - 0.0017 18.1 0.1 0.0057 16.5 0.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain GKAP PF03359.13 KER31245.1 - 1.1e-10 41.6 0.5 1.1e-10 41.6 0.5 2.2 1 1 1 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein MRP-L47 PF06984.13 KER31246.1 - 2.3e-31 107.8 1.0 5e-31 106.7 1.0 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) SRI PF08236.11 KER31247.1 - 0.14 12.4 3.5 0.47 10.7 3.5 1.8 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain CAP_N PF01213.19 KER31247.1 - 1.9 7.9 22.2 6 6.3 12.4 3.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Arb2 PF09757.9 KER31248.1 - 0.15 11.1 0.2 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Arb2 domain RVT_1 PF00078.27 KER31251.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3719 PF12516.8 KER31252.1 - 1.5e-07 31.0 1.4 8.8e-07 28.5 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) EF-hand_7 PF13499.6 KER31253.1 - 3e-13 50.0 4.2 0.3 11.6 0.0 7.3 8 0 0 8 8 8 4 EF-hand domain pair EF-hand_6 PF13405.6 KER31253.1 - 1.5e-12 46.4 4.7 0.26 11.3 0.2 7.6 7 0 0 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 KER31253.1 - 4.2e-05 22.8 0.1 0.38 10.4 0.0 5.3 5 0 0 5 5 5 1 EF hand RST PF12174.8 KER31253.1 - 0.00047 20.0 0.0 3 7.8 0.0 5.3 5 1 1 6 6 6 1 RCD1-SRO-TAF4 (RST) plant domain DUF3905 PF13045.6 KER31253.1 - 0.083 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) JAKMIP_CC3 PF16034.5 KER31256.1 - 0.025 14.5 0.7 0.025 14.5 0.7 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain PH PF00169.29 KER31256.1 - 0.11 13.0 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 PH domain bZIP_1 PF00170.21 KER31256.1 - 0.89 9.7 4.9 0.53 10.4 1.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor Nnf1 PF03980.14 KER31256.1 - 1.2 9.5 5.2 4 7.9 1.0 3.0 3 0 0 3 3 3 0 Nnf1 SPRY PF00622.28 KER31258.1 - 3.1e-13 49.9 3.1 7.8e-07 29.2 0.1 2.7 3 0 0 3 3 3 2 SPRY domain PHD_4 PF16866.5 KER31258.1 - 0.31 11.2 1.5 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 KER31258.1 - 1.1 9.2 8.7 4.1 7.4 7.1 2.4 1 1 1 2 2 2 0 PHD-finger Zf_RING PF16744.5 KER31258.1 - 1.2 9.3 3.1 2.7 8.2 1.7 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger Macoilin PF09726.9 KER31259.1 - 4.9e-31 108.0 10.3 9.6e-31 107.1 10.3 1.4 1 1 0 1 1 1 1 Macoilin family Macoilin PF09726.9 KER31260.1 - 3.9e-16 58.8 12.3 3.9e-16 58.8 12.3 3.1 3 1 0 3 3 3 1 Macoilin family Trimer_CC PF08954.11 KER31260.1 - 0.0028 17.2 0.1 0.01 15.4 0.1 1.9 1 0 0 1 1 1 1 Trimerisation motif LURAP PF14854.6 KER31260.1 - 0.99 9.4 5.0 0.79 9.7 1.8 2.6 2 1 0 2 2 2 0 Leucine rich adaptor protein Neur_chan_LBD PF02931.23 KER31261.1 - 2.9e-32 111.9 0.0 6.4e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 KER31261.1 - 3.4e-07 30.6 0.3 1.2e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region Xpo1 PF08389.12 KER31263.1 - 2.6e-13 50.3 1.9 5.1e-13 49.3 0.1 2.6 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KER31263.1 - 0.0075 16.2 0.2 0.022 14.7 0.2 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain ADH_N PF08240.12 KER31264.1 - 1.1e-22 80.0 0.2 2.1e-22 79.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Exo_endo_phos PF03372.23 KER31264.1 - 0.0099 15.4 0.0 0.014 14.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pico_P1A PF02226.16 KER31265.1 - 0.016 15.2 0.2 0.057 13.5 0.2 1.9 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) NIL PF09383.10 KER31265.1 - 0.044 13.6 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 NIL domain ATG16 PF08614.11 KER31265.1 - 0.18 12.0 113.2 0.063 13.5 0.7 7.2 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) DUF5631 PF18645.1 KER31265.1 - 7.6 7.0 7.6 0.53 10.7 0.5 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5631) ApbA_C PF08546.11 KER31265.1 - 8.3 6.6 7.8 0.59 10.3 1.6 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Fea1 PF07692.11 KER31266.1 - 0.055 12.5 0.1 0.079 12.0 0.1 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein Inhibitor_I78 PF11720.8 KER31266.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Cbl_N PF02262.16 KER31267.1 - 6.4e-45 152.2 0.4 1.4e-44 151.1 0.4 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 KER31267.1 - 2.8e-40 136.1 0.0 4.8e-40 135.3 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 KER31267.1 - 1.9e-33 115.0 2.1 5.9e-33 113.4 2.1 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 KER31267.1 - 3.5e-12 46.0 7.1 3.5e-12 46.0 7.1 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KER31267.1 - 3.4e-11 42.8 5.5 3.4e-11 42.8 5.5 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER31267.1 - 1.6e-06 28.3 8.1 1.6e-06 28.3 8.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KER31267.1 - 5.3e-06 26.2 9.0 5.3e-06 26.2 9.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER31267.1 - 6.9e-05 22.7 7.4 6.9e-05 22.7 7.4 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER31267.1 - 9.3e-05 22.4 6.4 0.00032 20.7 6.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KER31267.1 - 0.00048 19.9 8.8 0.0013 18.5 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KER31267.1 - 0.00059 19.6 6.2 0.00059 19.6 6.2 2.3 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain Glyco_trans_1_4 PF13692.6 KER31268.1 - 0.00029 21.3 0.0 0.00045 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KER31268.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KER31268.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KER31268.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 TM2 PF05154.16 KER31269.1 - 1.4e-16 60.5 8.8 3e-16 59.5 8.8 1.5 1 0 0 1 1 1 1 TM2 domain Glyco_hydro_65m PF03632.15 KER31271.1 - 4.7e-49 167.2 0.0 1.7e-21 76.6 0.1 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain Pkinase PF00069.25 KER31272.1 - 4.5e-66 222.9 0.0 6.3e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31272.1 - 6e-33 114.2 0.0 9.1e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 KER31272.1 - 1.3e-27 95.7 0.1 1.3e-16 60.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 KER31272.1 - 3.4e-05 23.3 0.0 5.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KER31272.1 - 0.023 14.7 0.0 0.57 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER31272.1 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2064 PF09837.9 KER31272.1 - 0.031 14.1 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Pkinase_fungal PF17667.1 KER31272.1 - 0.042 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPT PF03151.16 KER31275.1 - 5.4e-06 26.0 12.8 1.1e-05 25.0 12.8 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family RVT_1 PF00078.27 KER31276.1 - 0.00078 19.0 0.0 0.00078 19.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G_2 PF16999.5 KER31277.1 - 0.74 10.3 4.2 1.4 9.4 4.2 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Kinesin PF00225.23 KER31279.1 - 2.1e-36 125.5 6.4 2.3e-22 79.4 0.0 3.1 3 1 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KER31279.1 - 7.4e-23 81.1 0.2 4.4e-22 78.6 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding CREPT PF16566.5 KER31279.1 - 3.6 7.8 12.9 1.4 9.1 0.5 2.8 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3450 PF11932.8 KER31279.1 - 9.5 5.4 14.0 5.9 6.1 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Peroxidase_ext PF11895.8 KER31280.1 - 0.13 12.3 0.6 0.4 10.7 0.6 1.8 1 0 0 1 1 1 0 Fungal peroxidase extension region Forkhead PF00250.18 KER31281.1 - 1.1e-35 121.7 0.0 2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain SPRY PF00622.28 KER31282.1 - 1.7e-22 79.8 0.0 3.6e-15 56.1 0.0 2.7 2 0 0 2 2 2 2 SPRY domain FERM_M PF00373.18 KER31282.1 - 1e-18 67.8 0.0 1.9e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 KER31282.1 - 1.1e-16 61.0 0.0 2.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 KER31282.1 - 9.8e-14 51.1 0.0 1.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Nipped-B_C PF12830.7 KER31284.1 - 8.7e-68 228.0 3.6 5.2e-66 222.2 0.1 3.7 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KER31284.1 - 2.2e-10 40.7 5.9 2.8e-10 40.3 2.6 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KER31284.1 - 1.3e-09 38.3 4.7 0.02 15.0 0.3 4.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KER31284.1 - 0.00027 20.9 7.3 1.9 9.0 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KER31284.1 - 0.0035 17.7 0.5 0.0035 17.7 0.5 5.1 5 1 0 5 5 5 1 HEAT repeats AAA_18 PF13238.6 KER31284.1 - 4.9 7.7 5.9 2.2 8.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain HEAT_EZ PF13513.6 KER31284.1 - 7.3 7.2 8.8 0.71 10.4 0.7 3.9 3 1 0 3 3 3 0 HEAT-like repeat DHHC PF01529.20 KER31287.1 - 1.1e-33 116.2 17.6 1.1e-33 116.2 17.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase MatC_N PF07158.11 KER31287.1 - 2.2 8.3 6.0 1.5 8.8 0.4 2.3 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus Pkinase PF00069.25 KER31289.1 - 1.6e-69 234.2 0.0 9.4e-45 153.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER31289.1 - 4.8e-38 130.9 0.0 4.9e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase AdenylateSensor PF16579.5 KER31289.1 - 6.1e-13 49.3 0.2 2.2e-12 47.5 0.1 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KER31289.1 - 1.8e-06 27.5 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KER31289.1 - 0.00039 20.1 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KER31289.1 - 0.017 14.1 0.2 0.025 13.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KER31289.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER31289.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HD_3 PF13023.6 KER31290.1 - 8.5e-42 142.9 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KER31290.1 - 9.5e-12 45.0 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KER31290.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain ELM2 PF01448.24 KER31291.1 - 5e-09 36.8 0.1 1.8e-08 35.0 0.1 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 KER31291.1 - 6.3e-07 29.5 0.0 0.00013 22.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KER31291.1 - 0.00047 20.0 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KER31291.1 - 0.011 16.0 0.1 0.053 13.8 0.0 2.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain COBRA1 PF06209.13 KER31296.1 - 2.1e-28 99.5 3.0 2.1e-11 43.4 0.4 3.2 3 0 0 3 3 3 3 Cofactor of BRCA1 (COBRA1) AAA_6 PF12774.7 KER31297.1 - 4.9e-158 525.3 0.0 2.5e-156 519.7 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KER31297.1 - 4.8e-137 457.3 2.4 4.8e-137 457.3 2.4 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 KER31297.1 - 1.8e-113 378.9 0.0 5.7e-113 377.2 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 KER31297.1 - 1e-89 299.5 0.3 1e-89 299.5 0.3 2.2 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER31297.1 - 6.1e-79 263.7 0.0 7.4e-77 256.9 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 KER31297.1 - 2.9e-63 213.6 1.6 3.1e-35 121.7 0.0 4.2 2 1 1 3 3 3 3 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 KER31297.1 - 2.2e-59 200.0 0.0 1.2e-58 197.6 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER31297.1 - 4.9e-47 158.9 0.0 1.1e-43 148.2 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KER31297.1 - 4.8e-42 144.2 3.5 9.9e-42 143.2 3.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KER31297.1 - 7.5e-35 119.8 0.1 3.4e-34 117.7 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 KER31297.1 - 1.4e-18 67.3 0.0 1.6e-08 34.6 0.0 5.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 KER31297.1 - 1.7e-16 60.2 0.2 7.3e-16 58.2 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 KER31297.1 - 3.2e-06 27.6 0.0 0.027 14.9 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER31297.1 - 0.0001 22.6 0.1 0.77 10.0 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KER31297.1 - 0.0012 19.4 0.3 1.3 9.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KER31297.1 - 0.0012 19.2 0.0 2.4 8.5 0.0 4.3 4 0 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.22 KER31297.1 - 0.0015 18.9 0.1 1.9 8.9 0.0 4.1 3 0 0 3 3 3 1 RNA helicase Mg_chelatase PF01078.21 KER31297.1 - 0.0035 16.8 0.1 5.4 6.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KER31297.1 - 0.0093 15.1 0.8 0.034 13.2 0.0 2.4 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 KER31297.1 - 0.027 14.2 0.1 45 3.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KER31297.1 - 0.029 14.5 0.5 24 5.1 0.0 4.2 4 0 0 4 4 4 0 AAA domain SKA2 PF16740.5 KER31297.1 - 0.04 13.7 3.5 0.21 11.4 3.5 2.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_30 PF13604.6 KER31297.1 - 0.074 12.8 0.1 4.7 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KER31297.1 - 0.086 12.2 0.0 7.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein HSBP1 PF06825.12 KER31297.1 - 0.14 12.1 1.8 0.7 9.8 1.8 2.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SRPRB PF09439.10 KER31297.1 - 0.16 11.4 6.8 0.35 10.3 0.0 3.9 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit DivIC PF04977.15 KER31297.1 - 1.3 8.9 10.7 5.7 6.8 5.5 3.1 2 0 0 2 2 2 0 Septum formation initiator PEARLI-4 PF05278.12 KER31297.1 - 2.3 7.8 9.9 0.18 11.3 4.7 1.8 2 0 0 2 2 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) V-SNARE PF05008.15 KER31297.1 - 2.8 8.4 6.7 8.3 6.9 2.7 3.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus AAA_23 PF13476.6 KER31297.1 - 3.3 8.2 9.6 33 4.9 1.5 4.1 3 0 0 3 3 3 0 AAA domain DUF3782 PF12644.7 KER31297.1 - 5.7 7.2 5.7 19 5.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) RVT_1 PF00078.27 KER31298.1 - 3.2e-11 43.2 0.0 7.3e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 KER31301.1 - 2.5e-05 25.1 0.0 4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LicD PF04991.13 KER31302.1 - 4.5e-10 40.0 0.5 8.1e-10 39.2 0.5 1.4 1 0 0 1 1 1 1 LicD family LicD PF04991.13 KER31303.1 - 1.3e-10 41.8 3.0 7.2e-09 36.1 3.1 2.2 1 1 1 2 2 2 2 LicD family Gp138_N PF18352.1 KER31304.1 - 0.17 11.9 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain YopE_N PF09020.10 KER31305.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 YopE, N terminal GCP_C_terminal PF04130.13 KER31306.1 - 1.5e-76 257.8 6.9 1.5e-76 257.8 6.9 2.6 4 0 0 4 4 4 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KER31306.1 - 1.2e-60 205.7 0.0 2.1e-60 204.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal CIAPIN1 PF05093.13 KER31307.1 - 6.5e-06 26.6 2.6 6.5e-06 26.6 2.6 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KER31307.1 - 0.00047 20.4 0.0 0.0009 19.5 0.0 1.5 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus SNF5 PF04855.12 KER31310.1 - 1.4e-56 192.0 0.9 1.8e-30 106.5 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 CRC_subunit PF08624.10 KER31310.1 - 0.0012 19.3 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TRAPP PF04051.16 KER31311.1 - 8.6e-32 109.9 0.0 1e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Lantibiotic_a PF14867.6 KER31311.1 - 0.078 12.7 1.2 0.13 12.1 1.2 1.3 1 0 0 1 1 1 0 Lantibiotic alpha Myb_Cef PF11831.8 KER31312.1 - 1e-68 231.5 5.1 1e-68 231.5 5.1 3.1 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 KER31312.1 - 1.5e-19 70.0 5.8 2.2e-11 43.8 2.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KER31312.1 - 3.1e-18 65.7 5.2 2.8e-08 33.8 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain TPR_14 PF13428.6 KER31314.1 - 4.7e-19 67.5 33.3 1.2 10.2 0.1 15.3 11 3 4 15 15 15 6 Tetratricopeptide repeat Suf PF05843.14 KER31314.1 - 1.2e-14 55.0 5.0 3.5e-05 24.0 0.2 6.5 6 1 1 7 7 7 4 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KER31314.1 - 2.7e-12 46.5 14.2 0.00079 18.6 0.0 7.5 4 3 1 6 6 6 3 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 KER31314.1 - 6.8e-09 35.2 31.3 0.18 12.0 0.0 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KER31314.1 - 2.5e-06 27.5 16.4 0.19 11.7 0.3 8.4 6 2 2 8 8 8 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KER31314.1 - 4.9e-05 23.5 20.4 5.2 7.4 0.3 7.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER31314.1 - 0.00094 19.6 19.9 0.42 11.2 0.0 8.3 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER31314.1 - 0.00095 19.2 20.1 1.8 9.0 0.1 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER31314.1 - 0.0042 17.4 13.6 42 4.9 0.0 7.8 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 KER31314.1 - 0.011 15.9 3.0 92 3.6 0.0 5.7 6 0 0 6 6 5 0 PPR repeat APOBEC_C PF05240.14 KER31314.1 - 0.016 15.2 6.7 34 4.5 0.1 5.1 5 0 0 5 5 5 0 APOBEC-like C-terminal domain FliS PF02561.14 KER31314.1 - 0.017 15.4 0.0 20 5.5 0.0 3.5 2 0 0 2 2 2 0 Flagellar protein FliS DUF412 PF04217.13 KER31314.1 - 0.12 12.3 0.3 24 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Phenol_hyd_sub PF06099.11 KER31314.1 - 0.17 11.9 0.3 43 4.2 0.0 3.0 2 0 0 2 2 2 0 Phenol hydroxylase subunit Dynein_attach_N PF15867.5 KER31314.1 - 0.24 11.4 1.6 22 5.1 0.1 2.5 2 0 0 2 2 2 0 Dynein attachment factor N-terminus TPR_1 PF00515.28 KER31314.1 - 0.66 9.9 0.0 0.66 9.9 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31314.1 - 4.4 8.2 19.9 21 6.0 0.1 7.2 8 0 0 8 8 4 0 Tetratricopeptide repeat Tex_YqgF PF16921.5 KER31315.1 - 2.7e-37 128.0 0.0 5.2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain Tex_N PF09371.10 KER31315.1 - 2.8e-32 111.9 0.0 5.3e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.7 KER31315.1 - 1.2e-22 79.9 0.0 2.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 KER31315.1 - 4.8e-12 46.6 0.0 1.6e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 KER31315.1 - 7.3e-08 32.6 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 KER31315.1 - 1.8e-05 25.0 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KER31315.1 - 0.00051 19.8 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 KER31315.1 - 0.00055 19.8 0.0 0.0018 18.0 0.0 1.9 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_5 PF14520.6 KER31315.1 - 0.22 12.1 0.9 3.3 8.4 0.3 3.2 3 1 1 4 4 4 0 Helix-hairpin-helix domain Cystatin PF00031.21 KER31316.1 - 1.6e-07 31.5 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Tautomerase PF01361.21 KER31316.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Tautomerase_2 PF14552.6 KER31316.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Tautomerase enzyme Cystatin PF00031.21 KER31318.1 - 1.5e-05 25.1 0.1 2.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Cystatin domain NAD_binding_2 PF03446.15 KER31318.1 - 0.019 15.1 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Tautomerase_2 PF14552.6 KER31318.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme HIP1_clath_bdg PF16515.5 KER31319.1 - 0.00066 20.2 39.9 0.024 15.2 7.4 3.5 2 1 1 3 3 3 2 Clathrin-binding domain of Huntingtin-interacting protein 1 MscS_porin PF12795.7 KER31319.1 - 0.002 17.7 21.7 0.002 17.7 21.7 3.3 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain Filament PF00038.21 KER31319.1 - 0.0094 15.6 32.9 0.078 12.5 3.3 2.9 2 1 0 2 2 2 2 Intermediate filament protein ERM PF00769.19 KER31319.1 - 0.01 15.7 7.1 0.01 15.7 7.1 2.8 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Phosducin PF02114.16 KER31319.1 - 0.021 13.8 3.6 0.04 12.9 3.6 1.5 1 0 0 1 1 1 0 Phosducin HrpB7 PF09486.10 KER31319.1 - 0.1 13.0 29.9 0.095 13.1 16.1 3.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 KER31319.1 - 0.11 12.9 33.1 0.55 10.7 8.3 3.3 1 1 2 3 3 3 0 Fez1 DUF2730 PF10805.8 KER31319.1 - 0.23 11.6 14.7 0.046 13.8 3.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 KER31319.1 - 0.29 10.0 41.0 0.021 13.7 5.6 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 KER31319.1 - 0.61 9.6 40.7 0.52 9.9 8.2 3.2 3 1 0 3 3 3 0 PspA/IM30 family Laminin_II PF06009.12 KER31319.1 - 1.1 9.3 16.4 0.36 10.8 2.2 3.5 2 1 1 3 3 3 0 Laminin Domain II Fib_alpha PF08702.10 KER31319.1 - 1.3 9.2 18.7 0.73 10.0 0.5 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KER31319.1 - 1.3 9.0 15.9 1.8 8.5 1.0 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 KER31319.1 - 1.3 9.1 40.1 0.022 14.9 6.7 3.4 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 KER31319.1 - 1.7 9.0 26.0 0.079 13.3 4.5 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) SHE3 PF17078.5 KER31319.1 - 3.2 7.4 26.2 0.15 11.7 1.9 3.1 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 ApoO PF09769.9 KER31319.1 - 3.3 7.7 5.5 23 5.0 1.9 3.1 2 2 0 2 2 2 0 Apolipoprotein O Csm1_N PF18504.1 KER31319.1 - 3.3 8.1 32.8 1.5 9.2 0.7 5.2 3 2 1 5 5 5 0 Csm1 N-terminal domain TACC_C PF05010.14 KER31319.1 - 3.3 7.4 29.9 0.082 12.7 2.5 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 KER31319.1 - 3.4 7.9 44.5 0.52 10.5 20.5 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KER31319.1 - 3.9 7.5 42.8 2.7 8.0 15.8 4.1 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KER31319.1 - 4.2 7.6 43.9 0.42 10.8 8.0 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Acyl-CoA_dh_2 PF08028.11 KER31319.1 - 4.4 7.6 14.1 0.25 11.6 1.8 3.1 2 2 1 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1664 PF07889.12 KER31319.1 - 4.5 7.3 13.3 11 6.1 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 KER31319.1 - 6.3 7.2 13.1 2 8.8 5.9 3.1 2 1 1 3 3 3 0 Syntaxin-like protein DUF3584 PF12128.8 KER31319.1 - 7.9 3.9 32.8 0.66 7.4 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Dis3l2_C_term PF17877.1 KER31320.1 - 0.091 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal PCI PF01399.27 KER31321.1 - 1.6e-11 44.6 0.0 4.6e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 PCI domain GAT PF03127.14 KER31321.1 - 0.063 13.6 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 GAT domain ELP6 PF09807.9 KER31326.1 - 2.1e-06 27.3 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 RNase_T PF00929.24 KER31327.1 - 6.2e-13 49.6 0.0 1.2e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KER31327.1 - 0.099 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease WD40 PF00400.32 KER31331.1 - 0.0015 19.3 0.1 2.5 9.1 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31331.1 - 0.0019 18.5 0.0 0.15 12.3 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Phlebovirus_G2 PF07245.11 KER31331.1 - 0.041 12.4 0.3 0.17 10.3 0.2 1.9 2 0 0 2 2 2 0 Phlebovirus glycoprotein G2 Exo_endo_phos_2 PF14529.6 KER31331.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RhoGAP PF00620.27 KER31333.1 - 3.2e-10 40.0 0.0 3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain PRONE PF03759.13 KER31335.1 - 0.23 10.3 0.0 0.25 10.1 0.0 1.0 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Bax1-I PF01027.20 KER31339.1 - 5.9e-36 124.2 7.4 9e-36 123.6 7.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 rve PF00665.26 KER31339.1 - 9.7e-19 67.7 0.0 3.8e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 KER31339.1 - 0.00056 20.5 0.1 0.013 16.1 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KER31339.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Polyoma_coat PF00718.20 KER31339.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein MFS_1 PF07690.16 KER31342.1 - 2.8e-22 79.1 37.3 9.1e-17 61.0 9.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KER31342.1 - 0.00037 19.2 9.7 0.00037 19.2 9.7 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KER31342.1 - 0.00099 17.5 1.3 0.00099 17.5 1.3 2.5 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Gate PF07670.14 KER31342.1 - 1.4 9.2 7.5 1.6 9.1 3.7 3.0 2 1 1 3 3 3 0 Nucleoside recognition GIY-YIG PF01541.24 KER31343.1 - 0.0069 16.6 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain HS1_rep PF02218.15 KER31344.1 - 1.2e-51 172.7 19.2 5.7e-21 74.5 2.5 3.7 3 0 0 3 3 3 3 Repeat in HS1/Cortactin SH3_1 PF00018.28 KER31344.1 - 5.4e-15 54.7 0.1 9.8e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER31344.1 - 1.9e-12 46.8 0.2 3.3e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER31344.1 - 7.8e-10 38.3 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.6 KER31344.1 - 0.002 18.5 0.5 10 6.6 0.0 3.5 1 1 2 3 3 3 1 TMEM210 family Fez1 PF06818.15 KER31345.1 - 3.3e-05 24.4 0.3 3.3e-05 24.4 0.3 2.8 3 0 0 3 3 3 1 Fez1 Spc7 PF08317.11 KER31345.1 - 0.0065 15.4 2.8 0.041 12.8 0.5 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF4201 PF13870.6 KER31345.1 - 0.014 15.1 8.5 0.053 13.3 4.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 KER31345.1 - 0.064 13.5 4.9 6.5 7.0 3.0 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EMP24_GP25L PF01105.24 KER31345.1 - 0.2 11.6 3.8 0.31 10.9 1.0 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ATG16 PF08614.11 KER31345.1 - 0.26 11.5 9.3 1.4 9.2 2.6 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.8 KER31345.1 - 0.27 11.3 4.6 6.1 7.0 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) EzrA PF06160.12 KER31345.1 - 0.34 9.0 4.8 0.67 8.0 1.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1640 PF07798.11 KER31345.1 - 0.4 10.7 6.2 8.1 6.5 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) ADIP PF11559.8 KER31345.1 - 0.57 10.3 8.3 2.8 8.0 4.4 2.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-RRPl_C4 PF17026.5 KER31345.1 - 0.68 10.1 3.4 0.82 9.8 1.5 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Filament PF00038.21 KER31345.1 - 0.98 8.9 12.7 1.1 8.8 0.1 3.1 4 0 0 4 4 4 0 Intermediate filament protein FlxA PF14282.6 KER31345.1 - 1.2 9.1 9.3 1.7 8.6 1.6 3.5 3 0 0 3 3 2 0 FlxA-like protein Nnf1 PF03980.14 KER31345.1 - 3.4 8.1 7.7 5.6 7.4 3.4 2.9 2 0 0 2 2 2 0 Nnf1 YabA PF06156.13 KER31345.1 - 3.5 8.3 13.8 1.4 9.6 1.7 4.2 4 1 1 5 5 5 0 Initiation control protein YabA COG2 PF06148.11 KER31345.1 - 4 7.5 6.7 2.7 8.1 3.1 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.7 KER31345.1 - 4.5 6.7 15.1 1.8 8.0 6.6 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF4817 PF16087.5 KER31346.1 - 7.4e-07 28.9 0.0 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) DUF4713 PF15831.5 KER31346.1 - 0.055 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) TFIIA PF03153.13 KER31350.1 - 0.052 13.6 36.6 0.088 12.8 36.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KER31350.1 - 4.4 5.4 32.8 6.6 4.8 32.8 1.3 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 KER31351.1 - 5e-40 137.5 0.0 7.8e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31351.1 - 2.5e-20 72.9 0.0 6.6e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER31351.1 - 0.03 13.1 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KER31351.1 - 0.049 13.5 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIN_6 PF17146.4 KER31352.1 - 2.2e-23 82.6 0.0 4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KER31352.1 - 2.8e-19 69.0 0.2 5e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF1641 PF07849.11 KER31352.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) zf-FPG_IleRS PF06827.14 KER31352.1 - 5.7 6.9 6.5 3.8 7.5 0.4 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Nic96 PF04097.14 KER31353.1 - 0.1 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 MMTV_SAg PF01054.17 KER31353.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen CHORD PF04968.12 KER31354.1 - 1.1e-36 125.4 15.1 9.4e-26 90.3 10.2 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KER31354.1 - 5.3e-10 40.2 0.0 1e-09 39.2 0.0 1.5 1 0 0 1 1 1 1 CS domain EspF PF04806.12 KER31354.1 - 0.27 11.7 7.6 0.5 10.8 7.6 1.3 1 0 0 1 1 1 0 EspF protein repeat DUF3583 PF12126.8 KER31354.1 - 0.45 9.9 1.6 0.59 9.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) LptF_LptG PF03739.14 KER31356.1 - 0.052 12.4 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HemY_N PF07219.13 KER31356.1 - 0.14 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TRIQK PF15168.6 KER31356.1 - 0.18 11.7 0.5 0.33 10.9 0.5 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family HEAT_2 PF13646.6 KER31357.1 - 3e-09 37.2 5.7 0.003 17.9 0.0 6.5 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KER31357.1 - 7.1e-08 32.1 16.9 0.7 10.3 0.0 9.6 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 KER31357.1 - 2.2e-07 31.2 14.6 0.64 10.6 0.1 7.9 7 2 2 9 9 9 4 HEAT-like repeat RVT_1 PF00078.27 KER31357.1 - 0.00029 20.4 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnd1 PF12717.7 KER31357.1 - 0.00039 20.5 8.7 0.12 12.4 0.0 5.1 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KER31357.1 - 0.0014 18.7 0.6 0.11 12.6 0.1 3.1 3 0 0 3 3 3 1 Parkin co-regulated protein Myb_DNA-bind_6 PF13921.6 KER31358.1 - 0.058 13.6 0.1 0.078 13.2 0.1 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rho_GDI PF02115.17 KER31360.1 - 3.2e-17 62.9 0.1 3.7e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SAD_SRA PF02182.17 KER31360.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 SAD/SRA domain CBM32 PF18344.1 KER31360.1 - 0.045 13.6 0.1 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding module family 32 Rho_GDI PF02115.17 KER31361.1 - 1.8e-34 119.2 0.0 2.5e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor TilS PF09179.11 KER31361.1 - 0.039 14.5 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 TilS substrate binding domain SAD_SRA PF02182.17 KER31361.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.6 2 0 0 2 2 2 0 SAD/SRA domain TRH PF05438.12 KER31362.1 - 0.019 14.7 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) E1_DerP2_DerF2 PF02221.15 KER31365.1 - 4e-10 40.3 0.2 6.4e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 ML domain DUF5356 PF17309.2 KER31366.1 - 0.037 14.0 0.7 1.3 9.0 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5356) DUF3042 PF11240.8 KER31366.1 - 0.15 12.1 0.7 5.3 7.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) UQ_con PF00179.26 KER31367.1 - 1.7e-41 141.1 0.0 2.2e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER31367.1 - 0.00077 19.2 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER31367.1 - 0.0043 17.3 0.1 0.0068 16.7 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KER31367.1 - 0.071 13.0 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 UEV domain Raptor_N PF14538.6 KER31369.1 - 5.1e-46 156.3 0.0 1.1e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KER31369.1 - 2e-06 28.4 10.4 3.6 8.6 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KER31369.1 - 0.00065 19.7 0.1 0.03 14.6 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KER31369.1 - 0.013 15.8 0.0 0.061 13.7 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats ANAPC4_WD40 PF12894.7 KER31369.1 - 0.059 13.7 0.0 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Septum_form PF13845.6 KER31370.1 - 0.028 13.9 0.2 0.038 13.5 0.2 1.1 1 0 0 1 1 1 0 Septum formation Haspin_kinase PF12330.8 KER31372.1 - 2.6e-66 224.1 0.0 8.8e-56 189.4 0.0 2.2 1 1 1 2 2 2 2 Haspin like kinase domain Pkinase_Tyr PF07714.17 KER31372.1 - 0.00027 20.3 0.0 0.0011 18.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER31372.1 - 0.025 13.9 0.0 0.2 11.0 0.0 2.1 1 1 0 1 1 1 0 Protein kinase domain Fer4_24 PF18109.1 KER31372.1 - 0.13 12.5 0.0 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Imm52 PF15579.6 KER31372.1 - 0.16 11.9 0.3 20 5.1 0.0 2.4 1 1 1 2 2 2 0 Immunity protein 52 Pkinase_Tyr PF07714.17 KER31373.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4393 PF14337.6 KER31374.1 - 0.19 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Ank_2 PF12796.7 KER31375.1 - 8.8e-29 99.9 0.4 1.1e-14 54.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER31375.1 - 1.6e-26 92.3 3.2 2.5e-09 37.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PRKG1_interact PF15898.5 KER31375.1 - 3.7e-23 82.4 13.4 3.7e-23 82.4 13.4 2.6 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Ank PF00023.30 KER31375.1 - 5.1e-23 80.4 2.9 2.6e-05 24.5 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KER31375.1 - 1.4e-20 71.2 1.9 0.00056 20.2 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KER31375.1 - 2.5e-20 72.2 4.9 2.3e-09 37.3 0.2 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Cnn_1N PF07989.11 KER31375.1 - 0.2 11.9 5.1 0.74 10.0 5.1 2.0 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 KIAA1430 PF13879.6 KER31375.1 - 0.69 10.7 6.4 3.2 8.6 6.4 2.2 1 0 0 1 1 1 0 KIAA1430 homologue APG6_N PF17675.1 KER31375.1 - 2.6 8.6 9.5 6.9 7.2 7.8 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 KER31375.1 - 2.7 8.2 9.3 16 5.7 2.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KER31375.1 - 3.3 7.5 9.2 12 5.7 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.14 KER31375.1 - 3.7 8.0 10.1 4.1 7.8 1.8 2.7 1 1 1 2 2 2 0 Nnf1 Peptidase_M16_M PF16187.5 KER31380.1 - 1.6e-60 204.8 2.1 2.5e-60 204.2 2.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KER31380.1 - 2.7e-20 73.1 0.0 5e-14 52.7 0.0 3.4 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KER31380.1 - 9.8e-17 61.3 0.0 2.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Brix PF04427.18 KER31383.1 - 4.3e-33 115.1 0.0 4.2e-32 111.8 0.0 2.1 1 1 0 1 1 1 1 Brix domain NIPSNAP PF07978.13 KER31383.1 - 0.26 11.5 1.9 4.2 7.6 0.0 3.0 2 1 0 2 2 2 0 NIPSNAP Phosphodiest PF01663.22 KER31384.1 - 1.6e-61 208.9 0.5 2.1e-61 208.5 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase NPDC1 PF06809.11 KER31384.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) HemY_N PF07219.13 KER31384.1 - 0.16 12.2 0.2 0.26 11.5 0.2 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Paf67 PF10255.9 KER31385.1 - 2.9e-146 487.6 0.1 3.5e-146 487.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF2428 PF10350.9 KER31385.1 - 0.024 13.9 0.3 3.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) OB_NTP_bind PF07717.16 KER31386.1 - 0.028 14.8 2.5 0.64 10.4 0.3 2.3 1 1 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold TssO PF17561.2 KER31388.1 - 0.34 11.0 10.0 0.048 13.8 4.5 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO hDGE_amylase PF14701.6 KER31388.1 - 0.88 8.6 7.4 0.053 12.6 1.3 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain HTH_48 PF17906.1 KER31390.1 - 0.11 12.7 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF4078 PF13300.6 KER31391.1 - 1.4e-19 70.2 5.0 1.4e-19 70.2 5.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CHASE3 PF05227.13 KER31391.1 - 0.63 9.9 9.7 2.6 8.0 0.4 2.8 2 0 0 2 2 2 0 CHASE3 domain Vir_act_alpha_C PF10400.9 KER31391.1 - 9.8 6.9 12.0 3.9 8.2 0.2 3.0 3 0 0 3 3 3 0 Virulence activator alpha C-term TSSC4 PF15264.6 KER31392.1 - 3.9e-07 30.4 2.4 3.9e-07 30.4 2.4 2.4 2 1 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 DUF3474 PF11960.8 KER31392.1 - 0.32 11.2 3.5 0.14 12.4 0.6 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3474) Sec7 PF01369.20 KER31396.1 - 8.3e-63 211.4 0.0 1.4e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KER31396.1 - 2.5e-23 82.7 4.0 1.9e-21 76.6 0.2 3.9 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KER31396.1 - 0.023 14.4 0.0 0.072 12.7 0.0 1.9 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3715 PF12509.8 KER31398.1 - 2.3e-35 121.8 0.0 6.6e-35 120.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) Ribosomal_L16 PF00252.18 KER31400.1 - 1.8e-43 147.7 0.1 2.3e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TSP_1 PF00090.19 KER31401.1 - 3.2e-08 33.7 7.7 1.3e-07 31.7 7.7 2.2 1 0 0 1 1 1 1 Thrombospondin type 1 domain EGF PF00008.27 KER31401.1 - 4.8e-05 23.6 42.7 0.004 17.4 5.8 6.2 5 1 0 5 5 5 3 EGF-like domain EGF_2 PF07974.13 KER31401.1 - 0.015 15.6 2.4 0.015 15.6 2.4 6.5 6 3 0 6 6 6 0 EGF-like domain hEGF PF12661.7 KER31401.1 - 0.018 15.7 2.7 0.018 15.7 2.7 6.9 6 3 0 6 6 6 0 Human growth factor-like EGF Cg6151-P PF10233.9 KER31401.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P WD40 PF00400.32 KER31403.1 - 2.6e-16 59.7 13.6 6.8e-05 23.6 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31403.1 - 2.5e-08 34.1 0.0 0.018 15.3 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER31403.1 - 0.0012 17.6 0.0 0.0025 16.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KER31403.1 - 0.069 12.5 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Takusan PF04822.13 KER31405.1 - 0.0029 17.5 4.4 0.0029 17.5 4.4 10.0 7 3 4 11 11 11 2 Takusan APG6_N PF17675.1 KER31405.1 - 0.0062 17.1 31.5 0.0094 16.5 11.1 11.4 4 4 5 10 10 10 5 Apg6 coiled-coil region DUF3510 PF12022.8 KER31405.1 - 0.0096 16.3 0.6 0.0096 16.3 0.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) L31 PF09784.9 KER31405.1 - 7.3 7.1 9.9 60 4.1 0.6 4.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 Filamin PF00630.19 KER31407.1 - 6.3e-255 826.8 18.7 1.5e-19 70.7 0.0 21.9 21 1 1 22 22 22 20 Filamin/ABP280 repeat CH PF00307.31 KER31407.1 - 2.1e-37 127.6 1.6 1.8e-20 73.1 2.4 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 KER31407.1 - 2e-14 53.2 9.1 0.72 9.9 0.0 10.2 11 0 0 11 11 11 5 Y_Y_Y domain Big_3_5 PF16640.5 KER31407.1 - 8.5e-12 45.1 21.0 0.0084 16.3 0.2 11.6 13 0 0 13 13 13 4 Bacterial Ig-like domain (group 3) CAMSAP_CH PF11971.8 KER31407.1 - 8.9e-05 22.2 0.0 0.75 9.7 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain Invasin_D3 PF09134.10 KER31407.1 - 0.0072 16.6 6.3 3 8.2 0.1 7.1 9 0 0 9 9 9 1 Invasin, domain 3 DUF5060 PF16586.5 KER31407.1 - 0.011 16.1 2.0 2.1e+02 2.3 0.0 7.6 9 0 0 9 9 9 0 Domain of unknown function (DUF5060) CH_2 PF06294.11 KER31407.1 - 0.21 11.7 0.4 12 6.1 0.3 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein Big_7 PF17957.1 KER31407.1 - 7.2 7.5 12.8 7.1 7.5 0.1 5.7 6 0 0 6 6 6 0 Bacterial Ig domain Chorein_N PF12624.7 KER31408.1 - 5.3e-12 45.9 0.3 1.3e-11 44.6 0.3 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Phosducin PF02114.16 KER31409.1 - 1.7e-46 158.3 0.1 4.6e-46 156.9 0.1 1.6 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KER31409.1 - 1.1e-05 25.3 0.1 2.7e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Sugar_tr PF00083.24 KER31412.1 - 1.4e-63 215.3 28.1 2.4e-63 214.6 28.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER31412.1 - 4.6e-17 62.0 55.8 6.3e-14 51.7 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C1 PF00112.23 KER31414.1 - 3.4e-67 226.7 3.3 4.2e-67 226.4 3.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 KER31414.1 - 8e-15 54.5 0.0 1.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 KER31414.1 - 0.12 11.1 3.8 0.9 8.2 1.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Presenilin PF01080.17 KER31416.1 - 1.1 8.0 4.5 1.3 7.7 4.5 1.3 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KER31416.1 - 1.5 8.6 13.1 2 8.2 13.1 1.1 1 0 0 1 1 1 0 SPX domain Zip PF02535.22 KER31416.1 - 6.9 5.8 7.4 2.4 7.3 4.8 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter 7tm_1 PF00001.21 KER31417.1 - 3.7e-47 160.8 2.5 4.9e-47 160.5 2.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER31417.1 - 1.1e-09 38.0 13.1 7.8e-07 28.7 6.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx zf-LITAF-like PF10601.9 KER31417.1 - 0.59 10.4 3.5 0.74 10.1 0.2 2.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PMT2_N PF17987.1 KER31418.1 - 0.13 12.4 0.8 0.26 11.5 0.8 1.5 1 1 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal RRM_1 PF00076.22 KER31419.1 - 1.1e-06 28.4 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.6 KER31422.1 - 3.4e-06 27.5 0.0 8.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SOCS_box PF07525.16 KER31422.1 - 6.7e-05 23.2 0.8 0.00015 22.0 0.8 1.6 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 KER31422.1 - 0.00023 21.7 0.0 0.00046 20.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) GDA1_CD39 PF01150.17 KER31422.1 - 0.022 13.5 0.1 0.03 13.0 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family C2 PF00168.30 KER31423.1 - 1.7e-50 169.6 0.0 3e-23 82.1 0.0 3.5 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 KER31423.1 - 1.1e-40 139.1 0.1 1.7e-40 138.4 0.1 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 KER31423.1 - 0.023 14.4 0.0 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Exo_endo_phos PF03372.23 KER31425.1 - 0.0062 16.1 0.0 0.0064 16.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER31425.1 - 0.063 13.1 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MutS_V PF00488.21 KER31427.1 - 4.1e-44 150.9 0.5 4.2e-39 134.5 0.1 2.5 3 0 0 3 3 3 2 MutS domain V MutS_III PF05192.18 KER31427.1 - 6.3e-21 75.5 0.0 3.8e-20 72.9 0.0 2.3 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KER31427.1 - 9e-08 32.5 0.0 5.5e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KER31427.1 - 6.9e-06 26.3 0.0 7.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 MutS family domain IV S10_plectin PF03501.15 KER31428.1 - 1.8e-34 117.7 0.0 2.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF4541 PF15074.6 KER31429.1 - 0.0029 18.2 0.2 0.013 16.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4541) FAM183 PF14886.6 KER31429.1 - 0.0034 18.1 1.9 0.012 16.3 1.9 2.0 1 1 0 1 1 1 1 FAM183A and FAM183B related SIR2 PF02146.17 KER31429.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Sir2 family BORA_N PF15280.6 KER31430.1 - 1.7e-11 44.2 0.2 5.2e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 Protein aurora borealis N-terminus LRRNT PF01462.18 KER31430.1 - 0.036 13.7 0.3 0.12 12.0 0.3 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain CNOT11 PF10155.9 KER31431.1 - 5.6e-41 139.6 3.4 5.6e-41 139.6 3.4 2.1 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 11 DUF2733 PF10813.8 KER31432.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) RRM_1 PF00076.22 KER31433.1 - 4e-35 119.5 0.1 6.2e-12 45.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER31433.1 - 0.0016 18.5 0.2 2.3 8.4 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif DND1_DSRM PF14709.7 KER31433.1 - 0.039 14.2 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 CH PF00307.31 KER31434.1 - 9.9e-69 228.4 4.0 1.4e-20 73.5 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER31434.1 - 5.3e-06 26.2 0.2 0.15 11.9 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KER31434.1 - 0.001 19.1 0.1 0.59 10.3 0.0 3.3 3 0 0 3 3 3 2 CH-like domain in sperm protein DUF3437 PF11919.8 KER31435.1 - 3e-29 100.8 1.0 7.3e-29 99.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 KER31435.1 - 6.6e-12 44.9 1.0 7e-08 31.6 0.1 3.6 4 0 0 4 4 4 2 Proteasome-substrate-size regulator, mid region CemA PF03040.14 KER31435.1 - 0.23 11.4 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 CemA family YhhN PF07947.14 KER31437.1 - 4.5e-36 124.2 15.6 5.7e-36 123.8 15.6 1.1 1 0 0 1 1 1 1 YhhN family DUF3188 PF11384.8 KER31437.1 - 0.47 10.2 3.5 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Fringe PF02434.16 KER31438.1 - 3.9e-11 42.9 0.1 1.2e-10 41.2 0.1 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KER31438.1 - 2.7e-07 30.6 0.0 5.3e-05 23.1 0.0 2.5 1 1 1 2 2 2 2 Galactosyltransferase WD40 PF00400.32 KER31440.1 - 4.5e-05 24.1 0.1 8.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat WD40 PF00400.32 KER31441.1 - 6.9e-30 102.7 15.4 1.7e-05 25.5 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31441.1 - 4.5e-07 30.1 0.0 0.81 10.0 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER31441.1 - 0.0014 18.0 0.0 0.038 13.3 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain IFT20 PF14931.6 KER31443.1 - 0.027 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FOXP-CC PF16159.5 KER31444.1 - 0.74 10.5 6.6 3.5 8.3 0.4 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain TFIIB PF00382.19 KER31445.1 - 8.4e-41 137.9 4.0 4e-24 84.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KER31445.1 - 1.8e-10 40.2 0.1 3.4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KER31445.1 - 1.7e-05 24.6 0.4 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 KER31445.1 - 0.00024 21.1 0.1 0.00042 20.4 0.1 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KER31445.1 - 0.017 15.2 0.4 3.9 7.6 0.2 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain MIF4G PF02854.19 KER31446.1 - 2.4e-50 171.2 6.7 2.2e-26 92.8 0.1 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KER31446.1 - 1.1e-18 68.3 3.6 2.9e-18 66.9 1.3 2.8 1 1 0 1 1 1 1 Up-frameshift suppressor 2 MLTR_LBD PF17765.1 KER31446.1 - 0.027 14.6 0.8 7.9 6.6 0.0 3.1 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain Synaptobrevin PF00957.21 KER31446.1 - 0.042 13.7 0.3 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 Synaptobrevin RRN3 PF05327.11 KER31446.1 - 0.46 9.0 5.1 0.58 8.6 0.6 3.0 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_12 PF13424.6 KER31448.1 - 3.7e-17 62.4 6.6 0.024 14.9 0.0 7.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KER31448.1 - 4.6e-17 62.3 14.8 2.9e-05 24.5 0.2 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KER31448.1 - 3.2e-16 58.1 22.5 0.00016 21.5 0.2 9.1 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KER31448.1 - 3.9e-14 51.8 20.9 0.0027 17.5 1.4 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31448.1 - 5e-14 52.3 14.5 1.8e-06 28.1 1.4 4.3 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KER31448.1 - 4e-10 39.7 11.3 0.059 14.0 0.6 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER31448.1 - 1.4e-08 34.3 19.1 0.038 14.2 0.0 7.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER31448.1 - 8.9e-08 32.3 8.6 11 7.2 0.0 8.5 6 2 3 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER31448.1 - 1.5e-06 27.8 20.6 0.017 15.1 0.2 9.1 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER31448.1 - 1.7e-05 24.9 0.7 1.9 8.7 0.0 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER31448.1 - 0.00015 22.4 10.4 0.0081 16.8 0.0 5.4 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KER31448.1 - 0.0089 15.9 11.8 0.27 11.2 0.0 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER31448.1 - 0.047 14.1 3.6 10 6.8 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER31448.1 - 0.047 13.8 10.2 1.1 9.4 0.8 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 KER31448.1 - 0.052 13.6 0.0 0.052 13.6 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF285 PF03382.14 KER31448.1 - 0.082 12.7 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF4810 PF16068.5 KER31448.1 - 0.15 12.6 6.0 25 5.5 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) Chibby PF14645.6 KER31449.1 - 4.4e-07 30.3 1.9 1.2e-06 28.9 0.0 2.6 2 0 0 2 2 2 1 Chibby family DUF3435 PF11917.8 KER31449.1 - 3 6.7 17.2 0.056 12.4 9.9 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3435) PWWP PF00855.17 KER31450.1 - 0.0082 16.5 0.4 0.041 14.3 0.4 2.2 1 1 0 1 1 1 1 PWWP domain ArfGap PF01412.18 KER31452.1 - 2.6e-38 130.7 0.3 6.6e-38 129.4 0.3 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 KER31452.1 - 7.8e-07 29.6 1.8 0.031 14.8 0.0 2.8 3 0 0 3 3 3 2 PH domain Ank_2 PF12796.7 KER31452.1 - 0.00035 21.1 0.0 0.00067 20.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH_6 PF15406.6 KER31452.1 - 0.0095 16.2 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_5 PF13857.6 KER31452.1 - 0.08 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PH_13 PF16652.5 KER31452.1 - 0.097 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Ras PF00071.22 KER31452.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Ras family Pkinase PF00069.25 KER31453.1 - 1.7e-63 214.5 0.0 3.2e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31453.1 - 2.6e-51 174.4 0.0 5.5e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 KER31453.1 - 2.7e-06 27.6 40.3 1.6e-05 25.0 11.9 5.2 5 1 0 5 5 5 2 Polo kinase kinase APH PF01636.23 KER31453.1 - 0.042 13.8 0.6 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nbl1_Borealin_N PF10444.9 KER31453.1 - 0.59 9.8 11.1 0.035 13.8 2.2 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF725 PF05267.12 KER31453.1 - 0.61 10.1 5.7 3 7.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF725) AsnA PF03590.15 KER31457.1 - 1.4e-97 325.9 0.9 1.9e-97 325.5 0.9 1.2 1 0 0 1 1 1 1 Aspartate-ammonia ligase Tagatose_6_P_K PF08013.11 KER31457.1 - 0.026 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase tRNA-synt_2 PF00152.20 KER31457.1 - 0.039 13.0 0.8 0.098 11.7 0.8 1.6 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Drf_FH3 PF06367.16 KER31459.1 - 2.7e-20 72.8 0.4 2.7e-20 72.8 0.4 1.7 2 0 0 2 2 2 1 Diaphanous FH3 Domain FH2 PF02181.23 KER31459.1 - 4.1e-05 22.9 4.2 0.16 11.0 0.0 3.2 3 0 0 3 3 3 2 Formin Homology 2 Domain HIP1_clath_bdg PF16515.5 KER31459.1 - 0.032 14.8 4.1 0.15 12.7 3.8 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC1 PF03109.16 KER31461.1 - 1.2e-30 106.1 0.0 2.1e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Metallophos PF00149.28 KER31463.1 - 1.4e-37 130.2 0.1 2e-37 129.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Guanylate_cyc PF00211.20 KER31464.1 - 5.2e-94 313.0 0.5 4e-49 166.7 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF5554 PF17709.1 KER31464.1 - 0.052 13.7 0.1 0.32 11.1 0.1 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5554) DUF512 PF04459.12 KER31464.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF3572 PF12096.8 KER31464.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) Guanylate_cyc PF00211.20 KER31465.1 - 5.8e-39 133.6 0.9 1.5e-25 89.9 0.2 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Tis11B_N PF04553.12 KER31466.1 - 3.3 8.3 11.1 7.1 7.2 2.9 2.7 1 1 2 3 3 3 0 Tis11B like protein, N terminus BORCS6 PF10157.9 KER31467.1 - 3.6e-27 95.5 0.5 1e-26 94.0 0.5 1.8 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 FKBP_C PF00254.28 KER31468.1 - 5e-20 71.6 0.1 3.2e-19 69.0 0.3 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 KER31468.1 - 6.3e-11 41.6 0.8 4.1e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat RVT_1 PF00078.27 KER31468.1 - 7.5e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.17 KER31468.1 - 6.4e-08 32.1 0.4 0.0002 21.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER31468.1 - 2.6e-05 24.6 0.1 0.004 17.9 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER31468.1 - 6.4e-05 23.5 0.0 0.013 16.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 KER31468.1 - 9.7e-05 22.4 0.0 0.031 14.4 0.0 3.1 3 1 0 3 3 2 1 BDBT FKBP like N-terminal TPR_6 PF13174.6 KER31468.1 - 0.0001 22.7 0.1 0.029 15.0 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER31468.1 - 0.00018 21.7 2.0 0.52 10.6 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat gag-asp_proteas PF13975.6 KER31468.1 - 0.00081 19.9 0.0 0.0077 16.8 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TPR_19 PF14559.6 KER31468.1 - 0.00089 19.7 0.2 0.046 14.2 0.0 2.4 2 1 2 4 4 3 2 Tetratricopeptide repeat RVP PF00077.20 KER31468.1 - 0.0035 17.6 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KER31468.1 - 0.024 15.3 0.0 0.12 13.0 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RPN7 PF10602.9 KER31468.1 - 0.027 14.2 1.0 0.05 13.3 1.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KER31468.1 - 0.06 13.8 0.8 0.39 11.2 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KER31468.1 - 0.066 13.6 0.2 0.2 12.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31468.1 - 0.086 13.1 0.5 0.25 11.6 0.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KER31468.1 - 0.098 12.9 0.0 4.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER31468.1 - 0.21 11.7 0.7 4.1 7.6 0.0 2.8 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat UPF0029 PF01205.19 KER31469.1 - 0.1 13.0 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Spectrin PF00435.21 KER31470.1 - 8.6e-18 64.8 43.8 4.7e-05 23.8 1.5 9.1 7 1 0 8 8 8 5 Spectrin repeat PH_9 PF15410.6 KER31470.1 - 4.4e-12 46.4 0.0 1.5e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KER31470.1 - 1.7e-05 25.3 0.0 6.5e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 PH domain DUF1664 PF07889.12 KER31470.1 - 3.7 7.6 11.1 0.39 10.7 1.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 KER31471.1 - 5.4e-08 33.3 12.7 1.1e-07 32.3 5.7 2.6 2 0 0 2 2 2 2 Spectrin repeat RVT_1 PF00078.27 KER31471.1 - 9.1e-06 25.3 0.0 3.5e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlgN PF05130.12 KER31471.1 - 1.2 9.6 6.2 0.46 11.0 1.4 2.3 2 0 0 2 2 2 0 FlgN protein CH PF00307.31 KER31472.1 - 4.3e-22 78.4 0.3 3.3e-16 59.4 0.0 3.8 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER31472.1 - 1.9e-06 27.6 0.1 0.00084 19.1 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain Spectrin PF00435.21 KER31472.1 - 0.00013 22.4 3.0 0.00013 22.4 3.0 6.9 6 1 0 6 6 6 3 Spectrin repeat PB1 PF00564.24 KER31472.1 - 0.017 15.1 0.4 0.43 10.6 0.0 3.6 4 0 0 4 4 4 0 PB1 domain APO_RNA-bind PF05634.11 KER31472.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 APO RNA-binding Picorna_P3A PF06363.11 KER31472.1 - 0.14 12.0 0.0 7.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Picornaviridae P3A protein RMI2 PF16100.5 KER31473.1 - 0.052 13.4 0.3 0.51 10.2 0.2 2.2 1 1 1 2 2 2 0 RecQ-mediated genome instability protein 2 BEN PF10523.9 KER31474.1 - 0.0022 18.2 0.0 0.006 16.8 0.0 1.7 2 0 0 2 2 2 1 BEN domain Cep57_MT_bd PF06657.13 KER31474.1 - 0.061 13.8 2.8 0.07 13.6 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Gp_dh_N PF00044.24 KER31476.1 - 6.6e-20 71.3 0.0 2.6e-19 69.5 0.0 2.0 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KER31476.1 - 2.1e-13 50.1 0.0 6.3e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain QWRF PF04484.12 KER31476.1 - 0.65 9.7 0.0 0.65 9.7 0.0 2.3 2 1 1 3 3 3 0 QWRF family ASC PF00858.24 KER31477.1 - 1.1e-55 189.4 2.8 3.1e-55 187.9 2.8 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel C2 PF00168.30 KER31480.1 - 7.3e-11 42.3 0.0 6.3e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain MFS_1 PF07690.16 KER31481.1 - 9.8e-23 80.6 32.5 6.9e-18 64.7 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbE PF11100.8 KER31482.1 - 0.14 12.4 0.7 0.28 11.4 0.7 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbE Alpha_kinase PF02816.18 KER31483.1 - 4e-58 196.6 0.0 5.8e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 KER31483.1 - 5.9e-09 36.3 5.4 0.0028 18.3 0.5 4.6 4 0 0 4 4 4 2 Sel1 repeat GST_C_3 PF14497.6 KER31485.1 - 4.2e-11 42.9 0.0 6.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER31485.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER31485.1 - 2.5e-05 24.2 0.0 4.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER31485.1 - 5.7e-05 23.4 0.0 0.00026 21.2 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KER31485.1 - 0.00091 19.6 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER31485.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Diphthami_syn_2 PF01902.17 KER31486.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Cg6151-P PF10233.9 KER31488.1 - 3.7e-09 36.9 2.9 5.3e-09 36.4 2.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TraL PF07178.11 KER31488.1 - 0.031 14.8 0.1 0.057 13.9 0.1 1.4 1 0 0 1 1 1 0 TraL protein E1-E2_ATPase PF00122.20 KER31488.1 - 0.15 11.6 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Pkinase PF00069.25 KER31490.1 - 1.8e-06 27.5 0.0 0.00015 21.3 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain YlqD PF11068.8 KER31491.1 - 0.78 10.1 18.4 0.39 11.1 0.4 3.9 2 1 2 4 4 4 0 YlqD protein zf-3CxxC_2 PF17180.4 KER31491.1 - 0.95 10.2 3.0 1.6 9.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-binding domain GIT_CC PF16559.5 KER31491.1 - 2 8.4 14.5 1.3 9.0 0.1 4.2 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor NNMT_PNMT_TEMT PF01234.17 KER31492.1 - 0.18 10.9 0.2 18 4.4 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family GDPD PF03009.17 KER31493.1 - 5.4e-47 160.7 0.0 1.6e-43 149.3 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Ribosomal_L2_C PF03947.18 KER31495.1 - 2.5e-46 157.0 3.8 5.6e-46 155.8 3.8 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KER31495.1 - 2e-19 69.3 0.2 5.1e-19 68.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_8 PF13181.6 KER31497.1 - 0.0022 18.1 0.8 0.0022 18.1 0.8 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER31497.1 - 0.0036 17.3 7.6 0.0056 16.7 1.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER31497.1 - 0.0056 17.2 0.3 0.0056 17.2 0.3 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER31497.1 - 0.0062 16.3 2.3 0.031 14.1 2.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TraI PF07057.11 KER31497.1 - 0.035 14.2 0.1 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 DNA helicase TraI TPR_19 PF14559.6 KER31497.1 - 0.038 14.5 1.1 3 8.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER31497.1 - 0.073 13.4 0.3 0.23 11.8 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 KER31499.1 - 0.79 10.7 7.0 4.4 8.3 0.3 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat RRM_1 PF00076.22 KER31501.1 - 4.2e-07 29.7 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KER31501.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated NPR3 PF03666.13 KER31501.1 - 2.3 6.9 7.4 3 6.5 7.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 P21-Arc PF04062.14 KER31502.1 - 2.2e-64 216.7 0.0 2.4e-58 197.0 0.0 2.1 2 0 0 2 2 2 2 ARP2/3 complex ARPC3 (21 kDa) subunit RVT_1 PF00078.27 KER31502.1 - 1.4e-14 54.1 0.0 2.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NifU_N PF01592.16 KER31503.1 - 9.1e-51 171.3 0.1 8.1e-47 158.6 0.0 2.1 2 0 0 2 2 2 2 NifU-like N terminal domain Trypsin PF00089.26 KER31505.1 - 6.9e-12 45.7 0.0 1e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.11 KER31505.1 - 0.023 15.1 0.3 0.066 13.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) DUF2695 PF10905.8 KER31505.1 - 0.13 12.5 0.3 0.63 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) GCD14 PF08704.10 KER31509.1 - 1.1e-72 244.7 0.0 3.9e-69 233.1 0.0 2.0 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KER31509.1 - 3.5e-07 30.1 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KER31509.1 - 2.5e-06 27.4 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KER31509.1 - 1e-05 26.1 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 KER31509.1 - 0.0031 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_11 PF08241.12 KER31509.1 - 0.042 14.5 0.0 0.076 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KER31509.1 - 0.049 13.2 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 KER31510.1 - 4e-73 246.0 0.0 5.8e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31510.1 - 5.4e-44 150.4 0.0 7.8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KER31510.1 - 5.8e-13 48.4 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KER31510.1 - 1.4e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER31510.1 - 0.0015 18.2 0.5 0.0026 17.4 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KER31510.1 - 0.035 13.5 0.4 0.063 12.6 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER31510.1 - 0.054 12.4 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain dCMP_cyt_deam_1 PF00383.23 KER31516.1 - 1.9e-14 53.3 3.6 2.4e-14 53.1 3.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KER31516.1 - 2.6e-07 30.9 0.9 2.6e-07 30.9 0.9 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-CHY PF05495.12 KER31516.1 - 0.085 13.4 0.5 0.18 12.3 0.5 1.6 1 1 0 1 1 1 0 CHY zinc finger Adeno_E4_34 PF04528.13 KER31516.1 - 0.14 12.0 0.2 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region CMD PF02627.20 KER31516.1 - 0.2 11.7 2.6 0.33 11.0 2.6 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Trypsin PF00089.26 KER31519.1 - 7.6e-06 25.9 0.0 9.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KER31519.1 - 0.0052 17.1 0.5 0.0076 16.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) RVT_1 PF00078.27 KER31520.1 - 4.3e-19 68.9 0.0 1.4e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IMS PF00817.20 KER31520.1 - 4.2e-16 59.3 0.0 3.3e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 impB/mucB/samB family BRCT_2 PF16589.5 KER31520.1 - 2.2e-11 44.0 0.0 7.3e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 KER31520.1 - 2.4e-09 37.9 0.1 8.6e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain LIG3_BRCT PF16759.5 KER31520.1 - 5.9e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KER31520.1 - 2.3e-05 24.7 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KER31520.1 - 0.00016 21.6 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 KER31520.1 - 0.0022 18.2 0.1 0.029 14.7 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif Cyclin_N PF00134.23 KER31521.1 - 9.6e-13 48.0 1.1 5.4e-11 42.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 KER31521.1 - 0.00046 20.3 0.7 0.0019 18.3 0.1 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 KER31521.1 - 0.0009 19.2 0.6 1.1 9.4 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 KER31521.1 - 0.15 12.5 0.1 0.54 10.7 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain PUF PF00806.19 KER31523.1 - 1.3e-65 213.6 0.6 2.6e-09 36.3 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Band_7 PF01145.25 KER31525.1 - 1.3e-34 119.7 9.6 1.4e-32 113.1 2.2 2.3 2 0 0 2 2 2 2 SPFH domain / Band 7 family Exo_endo_phos_2 PF14529.6 KER31525.1 - 3e-07 30.3 0.2 6e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase GP68 PF17469.2 KER31525.1 - 0.00016 22.0 1.1 0.84 10.1 0.0 2.6 2 0 0 2 2 2 2 Phage protein Gp68 PGDYG PF14083.6 KER31525.1 - 0.0039 17.4 0.2 0.71 10.1 0.0 2.7 3 0 0 3 3 3 1 PGDYG protein pPIWI_RE_REase PF18154.1 KER31525.1 - 0.0045 16.9 0.1 4 7.4 0.0 2.8 2 0 0 2 2 2 2 REase associating with pPIWI_RE Band_7_1 PF13421.6 KER31525.1 - 0.016 14.9 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family WD40 PF00400.32 KER31526.1 - 1.8e-20 72.9 6.4 0.00076 20.3 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31526.1 - 2.6e-05 24.4 0.2 14 6.1 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain CAMSAP_CC1 PF17095.5 KER31526.1 - 0.25 11.2 1.3 0.48 10.3 1.3 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin GST_N PF02798.20 KER31528.1 - 3.4e-07 30.5 0.0 8.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KER31528.1 - 2.7e-06 27.5 0.0 4.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER31528.1 - 2.4e-05 24.5 0.0 3.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER31528.1 - 3e-05 24.0 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KER31528.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1910 PF08928.10 KER31530.1 - 0.083 12.9 0.0 3.3 7.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) CSD PF00313.22 KER31531.1 - 9.2e-17 60.7 0.0 1.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain MULE PF10551.9 KER31532.1 - 1.5e-21 76.6 0.0 3.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain GDA1_CD39 PF01150.17 KER31533.1 - 2.9e-64 217.3 0.0 8.2e-63 212.5 0.0 2.2 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family E1_DerP2_DerF2 PF02221.15 KER31534.1 - 3.2e-18 66.5 0.8 3.7e-13 50.1 0.9 2.1 1 1 0 2 2 2 2 ML domain Sulfotransfer_3 PF13469.6 KER31535.1 - 5.1e-16 59.7 0.0 1.1e-15 58.7 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Glyco_hydro_4 PF02056.16 KER31535.1 - 0.2 11.2 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Sulfotransfer_3 PF13469.6 KER31537.1 - 2.3e-31 109.9 0.0 4.1e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER31537.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain CoaE PF01121.20 KER31541.1 - 1.6e-22 80.1 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 KER31541.1 - 1e-06 29.0 0.0 9.6e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase-like Exo_endo_phos_2 PF14529.6 KER31541.1 - 6.1e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER31541.1 - 0.0022 17.5 0.0 0.0064 16.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_33 PF13671.6 KER31541.1 - 0.0047 17.1 0.0 0.025 14.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KER31541.1 - 0.0048 17.3 1.3 0.22 11.9 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.6 KER31541.1 - 0.0067 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KER31541.1 - 0.013 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KER31541.1 - 0.041 14.2 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KER31541.1 - 0.065 13.1 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KER31541.1 - 0.068 13.7 0.0 0.29 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KER31541.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KER31541.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase APG9 PF04109.16 KER31542.1 - 3.4e-138 461.7 4.7 4.4e-138 461.3 4.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Transglut_core PF01841.19 KER31544.1 - 1.5e-06 28.7 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily TnpV PF14198.6 KER31544.1 - 0.22 11.5 0.0 0.58 10.2 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Big_3_4 PF13754.6 KER31544.1 - 0.25 11.1 1.1 44 3.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function HNOBA PF07701.14 KER31545.1 - 1.9e-65 220.4 0.6 3.9e-65 219.4 0.6 1.6 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.20 KER31545.1 - 1.6e-54 184.3 0.0 2.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.15 KER31545.1 - 4.1e-50 169.9 0.2 6.8e-50 169.2 0.2 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KER31546.1 - 1.2e-105 350.9 3.6 4.4e-54 182.9 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain GrpE PF01025.19 KER31546.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 GrpE CUB PF00431.20 KER31547.1 - 0.011 16.1 0.0 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 CUB domain CUB PF00431.20 KER31548.1 - 1.7e-10 41.2 0.2 2.5e-10 40.6 0.2 1.3 1 1 0 1 1 1 1 CUB domain CUB PF00431.20 KER31549.1 - 2.2e-11 44.1 0.0 2.8e-08 34.1 0.0 3.3 4 1 0 4 4 4 2 CUB domain RVT_1 PF00078.27 KER31550.1 - 0.0001 21.9 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Flu_M1 PF00598.19 KER31550.1 - 0.056 12.9 0.0 9.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Influenza Matrix protein (M1) YqzL PF14006.6 KER31550.1 - 0.16 12.3 1.6 22 5.5 0.1 2.3 2 0 0 2 2 2 0 YqzL-like protein BRAP2 PF07576.12 KER31552.1 - 1.2e-27 96.1 0.1 2.5e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KER31552.1 - 2.3e-18 66.3 5.1 5.8e-18 65.0 5.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KER31552.1 - 1.7e-08 34.6 6.2 1.7e-08 34.6 6.2 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KER31552.1 - 8.9e-08 31.9 5.3 8.9e-08 31.9 5.3 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER31552.1 - 3.9e-06 26.8 5.6 2.1e-05 24.5 5.6 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER31552.1 - 1.1e-05 25.3 3.6 1.1e-05 25.3 3.6 2.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KER31552.1 - 5.8e-05 22.9 5.6 5.8e-05 22.9 5.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KER31552.1 - 0.00021 21.0 2.3 0.00021 21.0 2.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-UBP_var PF17807.1 KER31552.1 - 0.0052 16.5 0.5 0.017 14.9 0.5 1.9 1 0 0 1 1 1 1 Variant UBP zinc finger zf-C3HC4_4 PF15227.6 KER31552.1 - 0.0057 16.8 2.7 0.0057 16.8 2.7 2.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KER31552.1 - 0.0059 16.9 5.8 0.039 14.2 5.8 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KER31552.1 - 0.044 13.6 4.3 0.12 12.3 4.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 KER31552.1 - 0.051 13.6 4.3 0.2 11.7 4.3 2.1 1 1 0 1 1 1 0 Zinc-finger DUF4665 PF15679.5 KER31552.1 - 0.14 12.8 2.6 0.31 11.7 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) DUF948 PF06103.11 KER31552.1 - 0.21 11.8 1.3 0.73 10.1 1.3 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 KER31552.1 - 0.22 11.9 4.5 0.34 11.3 2.2 2.6 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KER31552.1 - 0.49 10.4 6.0 0.97 9.5 6.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KER31552.1 - 0.87 10.0 13.8 0.075 13.4 5.8 2.9 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 KER31552.1 - 1 8.8 9.6 1.6 8.2 9.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 KER31552.1 - 3.9 8.2 8.4 6.8 7.4 7.2 2.0 1 1 1 2 2 2 0 SlyX FapA PF03961.13 KER31552.1 - 8.5 4.9 9.9 12 4.3 9.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF719 PF05334.13 KER31554.1 - 5.8e-18 65.8 0.0 5.8e-18 65.8 0.0 3.4 3 2 1 4 4 4 1 Protein of unknown function (DUF719) DUF2631 PF10939.8 KER31554.1 - 0.0067 16.3 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2631) LRRFIP PF09738.9 KER31554.1 - 5.6 6.3 8.1 0.25 10.8 0.9 2.2 2 0 0 2 2 2 0 LRRFIP family zf-C2HC_2 PF13913.6 KER31555.1 - 2e-38 129.6 24.9 1.5e-11 43.9 1.9 4.6 5 0 0 5 5 5 4 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KER31555.1 - 0.00017 22.1 19.8 0.46 11.5 0.6 5.4 5 0 0 5 5 5 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31555.1 - 0.00043 20.6 2.3 3.5 8.2 0.0 4.5 4 1 0 4 4 4 1 Zinc-finger double domain RNF220 PF15926.5 KER31555.1 - 0.0014 18.3 1.1 7.1 6.2 0.0 3.1 1 1 2 3 3 3 1 E3 ubiquitin-protein ligase RNF220 zf-CHCC PF10276.9 KER31555.1 - 0.0016 18.4 6.1 0.33 11.0 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger domain Rad50_zn_hook PF04423.14 KER31555.1 - 0.0039 17.0 11.7 0.52 10.2 0.0 4.6 5 0 0 5 5 5 2 Rad50 zinc hook motif DUF2318 PF10080.9 KER31555.1 - 0.0042 17.2 5.6 5.8 7.1 0.3 4.0 4 0 0 4 4 4 1 Predicted membrane protein (DUF2318) zf-C2H2 PF00096.26 KER31555.1 - 0.016 15.6 13.3 5.9 7.5 0.1 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type FYVE PF01363.21 KER31555.1 - 0.021 15.0 7.2 3.9 7.7 0.1 3.9 4 0 0 4 4 4 0 FYVE zinc finger zf_UBZ PF18439.1 KER31555.1 - 0.039 13.5 5.2 3.9 7.2 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger ROS_MUCR PF05443.11 KER31555.1 - 0.056 13.5 0.1 3.5 7.7 0.0 2.6 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-CpG_bind_C PF12269.8 KER31555.1 - 0.066 13.0 4.7 5.3 6.7 0.2 3.1 1 1 2 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-HC5HC2H PF13771.6 KER31555.1 - 0.083 13.2 8.1 0.76 10.1 0.1 3.2 1 1 2 4 4 4 0 PHD-like zinc-binding domain Ribosomal_L32p PF01783.23 KER31555.1 - 0.094 13.0 2.2 8.1 6.8 0.0 3.2 3 0 0 3 3 2 0 Ribosomal L32p protein family DUF3762 PF12591.8 KER31555.1 - 0.12 12.6 3.3 0.36 11.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3762) DUF2256 PF10013.9 KER31555.1 - 0.14 12.3 10.4 32 4.7 0.2 4.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) RecR PF02132.15 KER31555.1 - 0.17 11.5 6.9 4.8 6.8 0.0 3.9 4 0 0 4 4 4 0 RecR protein HNH_5 PF14279.6 KER31555.1 - 0.25 11.2 5.1 18 5.2 0.2 3.8 4 0 0 4 4 4 0 HNH endonuclease zf-CCHC PF00098.23 KER31555.1 - 0.27 11.4 9.4 9.9 6.4 0.3 3.8 3 0 0 3 3 3 0 Zinc knuckle Zn-ribbon_8 PF09723.10 KER31555.1 - 0.32 11.2 10.4 8.8 6.5 0.1 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 KER31555.1 - 0.48 10.2 3.7 9.9 6.0 0.1 3.2 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Sgf11 PF08209.11 KER31555.1 - 0.98 9.0 12.6 21 4.8 0.3 4.3 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-RING_7 PF02591.15 KER31555.1 - 1.3 9.3 9.7 3 8.1 0.1 3.3 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_6 PF13912.6 KER31555.1 - 1.4 9.0 11.1 25 5.0 0.1 4.8 5 0 0 5 5 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KER31555.1 - 3.2 8.1 7.8 5.3 7.4 0.2 3.8 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding PseudoU_synth_1 PF01416.20 KER31556.1 - 1.8e-11 44.4 0.0 4.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridine synthase RVT_1 PF00078.27 KER31556.1 - 0.0036 16.8 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L4 PF00573.22 KER31557.1 - 2.8e-39 134.8 0.3 3.9e-39 134.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KER31557.1 - 1.3e-20 73.2 1.9 1.3e-20 73.2 1.9 2.8 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain DUF3913 PF13052.6 KER31557.1 - 0.0013 18.9 0.1 0.046 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3913) RVT_1 PF00078.27 KER31559.1 - 9.2e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCOR PF15808.5 KER31559.1 - 0.026 14.8 0.8 0.026 14.8 0.8 2.0 2 0 0 2 2 2 0 BCL-6 co-repressor, non-ankyrin-repeat region zf-H2C2_2 PF13465.6 KER31561.1 - 1e-17 63.6 26.1 1.2e-09 38.2 1.0 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KER31561.1 - 3.2e-17 61.9 20.9 9.4e-07 29.0 1.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31561.1 - 1.2e-12 47.5 19.0 0.00033 21.3 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KER31561.1 - 0.0034 17.1 25.4 0.0036 17.0 2.3 4.6 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KER31561.1 - 0.0063 16.5 13.7 0.43 10.6 1.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4698 PF15769.5 KER31561.1 - 0.012 14.7 0.5 0.018 14.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) zf-Di19 PF05605.12 KER31561.1 - 0.018 15.3 13.1 0.4 11.0 4.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KER31561.1 - 0.021 15.1 6.5 0.37 11.1 1.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KER31561.1 - 0.2 11.6 0.2 0.2 11.6 0.2 3.4 1 1 2 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 KER31561.1 - 0.69 10.3 9.9 2.9 8.3 1.0 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Ig_3 PF13927.6 KER31563.1 - 4.3e-55 184.3 8.1 8.2e-13 48.8 0.0 9.9 9 0 0 9 9 9 7 Immunoglobulin domain I-set PF07679.16 KER31563.1 - 4.2e-43 145.3 0.0 1.4e-12 47.5 0.0 7.4 6 1 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER31563.1 - 2.4e-28 98.3 10.0 1.3e-05 25.5 0.0 10.4 10 1 0 10 10 10 6 Immunoglobulin domain ig PF00047.25 KER31563.1 - 7.4e-28 96.6 9.2 1.1e-09 38.3 0.1 9.5 10 2 0 10 10 9 4 Immunoglobulin domain V-set PF07686.17 KER31563.1 - 3.2e-24 85.2 6.0 2.2e-07 31.0 0.0 7.9 7 1 0 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER31563.1 - 8.6e-18 64.2 5.5 2.3e-07 30.8 0.0 7.5 8 0 0 8 8 8 3 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 KER31563.1 - 3.6e-09 36.8 0.0 4.3e-08 33.4 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 KER31563.1 - 4.2e-05 23.5 0.0 5.2 7.2 0.0 4.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 KER31563.1 - 0.00019 20.3 0.1 0.81 8.4 0.0 3.0 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E Pur_ac_phosph_N PF16656.5 KER31563.1 - 0.00029 21.3 0.2 0.0013 19.3 0.2 2.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Ig_4 PF16680.5 KER31563.1 - 0.00047 20.4 0.2 1.8e+02 2.5 0.0 6.5 6 0 0 6 6 6 0 T-cell surface glycoprotein CD3 delta chain EphA2_TM PF14575.6 KER31563.1 - 0.0079 17.1 0.0 0.02 15.8 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KER31563.1 - 3.6 7.5 4.3 0.68 9.8 0.5 1.8 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain L51_S25_CI-B8 PF05047.16 KER31564.1 - 5.2e-08 32.7 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Peroxidase_ext PF11895.8 KER31564.1 - 0.022 14.7 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Fungal peroxidase extension region DUF842 PF05811.13 KER31565.1 - 1.1e-33 115.7 14.5 1.5e-33 115.3 14.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF2857 PF11198.8 KER31565.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Vanabin-2 PF11437.8 KER31565.1 - 0.11 12.6 12.7 0.95 9.7 6.1 2.8 1 1 1 2 2 2 0 Vanadium-binding protein 2 Muted PF14942.6 KER31565.1 - 0.14 12.5 5.4 0.2 12.0 1.9 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tom5 PF10642.9 KER31565.1 - 0.15 12.1 0.6 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase OmpH PF03938.14 KER31565.1 - 0.53 10.6 8.0 2.7 8.3 1.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2968 PF11180.8 KER31565.1 - 1.7 8.2 11.2 0.41 10.2 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Cation_efflux PF01545.21 KER31566.1 - 1.5e-48 165.2 5.1 2e-48 164.8 5.1 1.2 1 0 0 1 1 1 1 Cation efflux family VanZ PF04892.12 KER31566.1 - 0.069 13.8 0.3 0.2 12.3 0.3 1.8 1 0 0 1 1 1 0 VanZ like family zf_C2HC_14 PF18574.1 KER31566.1 - 4.4 7.2 5.1 0.52 10.1 0.6 1.8 2 0 0 2 2 2 0 C2HC Zing finger domain DUF2787 PF10980.8 KER31567.1 - 0.036 14.3 0.0 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2787) Nucleopor_Nup85 PF07575.13 KER31568.1 - 3e-50 171.4 0.0 2.1e-46 158.7 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin ACBP PF00887.19 KER31570.1 - 1.3e-22 79.8 0.4 1.8e-16 60.1 0.1 2.0 1 1 1 2 2 2 2 Acyl CoA binding protein Cadherin PF00028.17 KER31572.1 - 5.9e-50 167.7 0.0 9.6e-18 64.4 0.0 7.7 6 2 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 KER31572.1 - 0.00029 20.6 6.9 3.1 7.7 0.0 7.1 8 1 0 8 8 8 1 Cadherin-like Peptidase_M8 PF01457.16 KER31573.1 - 7.3e-09 34.8 0.0 9e-09 34.5 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 KER31574.1 - 2.5e-09 36.4 0.1 4.4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Leishmanolysin RecR PF02132.15 KER31575.1 - 0.11 12.1 2.0 0.21 11.2 2.0 1.4 1 0 0 1 1 1 0 RecR protein PRA1 PF03208.19 KER31576.1 - 3.2e-22 78.7 3.8 4.4e-22 78.3 3.8 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF295 PF03478.18 KER31576.1 - 0.068 12.8 0.3 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF295) DUF4395 PF14340.6 KER31576.1 - 0.46 10.8 5.6 0.83 10.0 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) DUF4131 PF13567.6 KER31576.1 - 4.7 6.8 5.7 19 4.8 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M8 PF01457.16 KER31578.1 - 6.4e-08 31.7 0.0 7.2e-07 28.3 0.0 1.9 1 1 0 1 1 1 1 Leishmanolysin SprT-like PF10263.9 KER31578.1 - 0.1 12.5 0.4 0.17 11.8 0.1 1.5 2 0 0 2 2 2 0 SprT-like family Peptidase_M8 PF01457.16 KER31579.1 - 0.00061 18.6 0.1 0.00073 18.3 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin HVSL PF09749.9 KER31580.1 - 2.1e-28 99.4 0.1 4.9e-26 91.7 0.1 2.1 1 1 0 1 1 1 1 Uncharacterised conserved protein HsdM_N PF12161.8 KER31580.1 - 0.0019 18.9 0.6 0.01 16.4 0.1 2.2 3 0 0 3 3 3 1 HsdM N-terminal domain zf-H2C2_2 PF13465.6 KER31583.1 - 6.8e-14 51.6 13.6 7.7e-07 29.3 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER31583.1 - 4.1e-13 49.0 17.2 0.00038 20.7 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31583.1 - 6.1e-09 36.0 14.7 0.0094 16.7 2.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER31583.1 - 0.00013 21.9 8.4 0.00067 19.6 1.9 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER31583.1 - 0.0098 16.2 1.9 0.78 10.1 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 KER31583.1 - 0.17 12.7 1.0 0.4 11.5 0.3 1.9 1 1 1 2 2 2 0 zinc-ribbon family zf-C2HE PF16278.5 KER31583.1 - 0.27 11.7 3.7 2.8 8.5 1.1 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KER31583.1 - 0.27 11.5 7.4 0.31 11.3 1.7 2.9 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 KER31583.1 - 1.8 8.5 11.4 8.5 6.4 0.6 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-AN1 PF01428.16 KER31583.1 - 6 7.1 6.3 29 4.9 1.1 2.9 1 1 1 2 2 2 0 AN1-like Zinc finger TPR_2 PF07719.17 KER31584.1 - 1.1e-08 34.5 10.9 0.075 13.2 0.6 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KER31584.1 - 4.9e-07 29.7 2.1 0.12 12.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER31584.1 - 1.9e-05 24.2 2.3 0.0021 17.7 0.0 4.1 6 0 0 6 6 6 1 TPR repeat TPR_1 PF00515.28 KER31584.1 - 0.0003 20.5 14.4 0.014 15.2 1.4 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER31584.1 - 0.00055 20.4 0.7 0.056 13.9 0.1 3.3 4 1 0 4 4 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER31584.1 - 0.001 19.3 3.2 0.025 14.8 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER31584.1 - 0.0019 18.3 10.4 0.1 12.9 0.5 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KER31584.1 - 0.0033 17.9 2.8 0.13 12.9 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER31584.1 - 0.0092 16.7 0.4 23 6.1 0.0 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31584.1 - 0.024 14.9 8.4 0.35 11.1 1.9 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KER31584.1 - 0.025 14.6 2.4 0.21 11.7 0.1 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF1835 PF08874.10 KER31584.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) RNase_3_N PF18497.1 KER31584.1 - 0.093 13.0 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain TPR_1 PF00515.28 KER31585.1 - 0.0038 17.0 1.1 0.021 14.7 1.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER31585.1 - 0.004 17.4 0.7 1.9 9.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER31585.1 - 0.0043 17.1 0.3 0.061 13.5 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER31585.1 - 0.0047 17.0 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER31585.1 - 0.008 16.4 0.9 0.25 11.7 0.2 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER31585.1 - 0.015 15.2 1.3 0.038 14.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KER31585.1 - 0.16 12.8 0.0 2 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Tetraspanin PF00335.20 KER31586.1 - 8.5e-44 150.0 19.9 9.8e-44 149.8 19.9 1.0 1 0 0 1 1 1 1 Tetraspanin family TMEM237 PF15383.6 KER31586.1 - 4.2 6.4 7.8 11 5.1 0.5 2.9 3 0 0 3 3 3 0 Transmembrane protein 237 Mtp PF03821.16 KER31587.1 - 5.5e-11 42.5 20.2 0.0014 18.3 1.3 4.2 3 1 1 4 4 4 4 Golgi 4-transmembrane spanning transporter 7TM_GPCR_Srj PF10319.9 KER31587.1 - 0.1 11.9 11.7 0.42 9.9 4.9 2.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj Peptidase_C92 PF05708.12 KER31587.1 - 0.22 11.6 1.5 21 5.2 0.1 2.2 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF4728 PF15860.5 KER31587.1 - 0.57 10.9 11.4 1.7 9.3 4.6 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) RRM_1 PF00076.22 KER31590.1 - 3.3e-06 26.8 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 KER31591.1 - 6.8e-22 76.3 136.3 0.0063 17.3 0.8 18.5 18 0 0 18 18 18 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31591.1 - 1.1e-14 54.1 80.9 0.00034 20.9 2.4 14.0 14 0 0 14 14 14 8 Zinc-finger double domain zf-C2H2 PF00096.26 KER31591.1 - 1.2e-10 41.3 138.4 0.00068 20.0 3.9 15.6 18 0 0 18 18 18 8 Zinc finger, C2H2 type zf-Di19 PF05605.12 KER31591.1 - 2.3e-05 24.6 11.4 9.4e-05 22.6 1.0 9.4 8 2 3 11 11 11 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KER31591.1 - 0.0096 15.7 33.5 0.023 14.4 0.4 8.2 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KER31591.1 - 0.025 15.2 51.5 0.056 14.1 0.1 9.5 3 2 6 9 9 9 0 Zinc finger C2H2-type, 3 repeats zf-CHCC PF10276.9 KER31591.1 - 5.9 7.0 20.6 1 9.5 0.7 5.3 6 0 0 6 6 6 0 Zinc-finger domain PCMT PF01135.19 KER31592.1 - 3.5e-71 239.3 0.0 4.3e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KER31592.1 - 0.00097 19.8 0.0 0.0025 18.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER31592.1 - 0.0015 18.4 0.0 0.0042 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KER31592.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KER31592.1 - 0.0043 17.2 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KER31592.1 - 0.013 16.2 0.0 0.036 14.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KER31592.1 - 0.037 13.6 0.2 0.11 12.1 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KER31592.1 - 0.054 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KER31592.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KER31592.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 KER31592.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 KER31592.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Tektin PF03148.14 KER31594.1 - 5.6e-128 426.9 50.0 8.9e-115 383.5 39.2 2.0 1 1 1 2 2 2 2 Tektin family Erf4 PF10256.9 KER31594.1 - 0.093 12.8 2.1 0.41 10.8 0.2 2.9 2 2 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family V-set_2 PF15910.5 KER31594.1 - 0.14 12.2 2.0 13 5.9 0.2 2.6 1 1 1 2 2 2 0 ICOS V-set domain TPR_22 PF18833.1 KER31594.1 - 0.21 11.7 9.1 2.4 8.3 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 KER31594.1 - 0.25 11.1 3.3 11 5.9 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin family DUF1664 PF07889.12 KER31594.1 - 0.26 11.4 24.0 0.84 9.7 3.3 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) V-SNARE_C PF12352.8 KER31594.1 - 0.43 10.9 3.9 26 5.2 0.1 3.6 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Seryl_tRNA_N PF02403.22 KER31594.1 - 0.97 9.7 32.2 0.099 12.9 5.9 5.0 4 2 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 KER31594.1 - 2.8 8.3 13.4 11 6.3 0.2 4.8 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KER31594.1 - 2.8 8.0 20.4 0.67 10.0 0.3 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 KER31594.1 - 4.9 7.8 31.8 0.15 12.7 1.4 5.5 5 1 0 5 5 5 0 SlyX LPP PF04728.13 KER31594.1 - 7.9 7.0 10.0 20 5.7 0.1 4.0 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF1759 PF03564.15 KER31596.1 - 6.4e-08 32.7 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) CHIP_TPR_N PF18391.1 KER31596.1 - 0.16 12.7 5.2 9.6 7.1 1.8 2.7 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain LLGL PF08366.13 KER31597.1 - 3e-05 24.3 0.1 6.8e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 LLGL2 PQQ_3 PF13570.6 KER31597.1 - 0.04 14.4 1.2 0.33 11.5 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain DnaJ PF00226.31 KER31602.1 - 4.9e-17 61.8 0.1 8.1e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Lactamase_B_2 PF12706.7 KER31604.1 - 3.9e-08 33.1 0.1 4.9e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KER31604.1 - 0.0015 18.6 0.8 0.0029 17.6 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily eIF-3_zeta PF05091.12 KER31605.1 - 2.3e-183 610.9 0.0 5.3e-183 609.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KER31605.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RRM_1 PF00076.22 KER31607.1 - 3.9e-16 58.6 0.0 1.7e-05 24.5 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM14 PF12701.7 KER31609.1 - 1.8e-10 40.7 0.0 4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain RVT_1 PF00078.27 KER31609.1 - 3.6e-08 33.2 0.0 6.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SM-ATX PF14438.6 KER31609.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain FDF PF09532.10 KER31609.1 - 0.13 13.2 0.0 8.5 7.3 0.0 2.5 2 0 0 2 2 2 0 FDF domain E1-E2_ATPase PF00122.20 KER31611.1 - 1.2e-32 112.9 0.2 2.4e-32 111.9 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KER31611.1 - 1.3e-21 77.0 0.3 3.6e-21 75.6 0.3 1.8 1 1 0 1 1 1 1 P5-type ATPase cation transporter Prot_ATP_ID_OB PF16450.5 KER31611.1 - 0.17 11.9 0.1 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Hydrolase PF00702.26 KER31612.1 - 3.8e-16 60.0 0.0 5.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER31612.1 - 9.2e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pkinase PF00069.25 KER31614.1 - 5e-74 249.0 0.0 7e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31614.1 - 2.2e-42 145.1 0.0 3.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KER31614.1 - 1.1e-18 66.7 0.0 2.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KER31614.1 - 1.1e-06 28.2 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 KER31614.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.14 KER31614.1 - 0.0079 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER31614.1 - 0.011 15.4 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family UBA_2 PF08587.11 KER31614.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Haspin_kinase PF12330.8 KER31614.1 - 0.21 10.5 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain NIF PF03031.18 KER31619.1 - 5.6e-08 32.7 0.1 6e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Meleagrin PF08189.11 KER31619.1 - 4 7.2 9.3 19 5.1 0.2 3.9 4 0 0 4 4 4 0 Meleagrin/Cygnin family LicD PF04991.13 KER31620.1 - 8.6e-09 35.9 0.1 0.015 15.4 0.0 3.4 3 0 0 3 3 3 3 LicD family Ribosomal_L7Ae PF01248.26 KER31624.1 - 6.4e-23 80.3 0.5 1.6e-22 79.1 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 KER31627.1 - 9.7e-67 225.1 0.0 1.3e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31627.1 - 4.5e-31 108.1 0.0 6.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER31627.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KER31627.1 - 0.014 15.3 1.4 0.046 13.7 1.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tub_N PF16322.5 KER31627.1 - 0.017 15.5 4.3 0.04 14.3 4.3 1.6 1 0 0 1 1 1 0 Tubby N-terminal Kdo PF06293.14 KER31627.1 - 0.17 11.2 0.5 0.35 10.2 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER31627.1 - 0.36 9.7 7.5 0.092 11.7 0.1 3.0 3 1 0 3 3 3 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 KER31628.1 - 4.4e-90 301.5 0.0 6.6e-90 300.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER31628.1 - 3.3e-41 141.4 0.0 5.1e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.17 KER31628.1 - 0.00028 21.0 0.1 0.00069 19.8 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain APH PF01636.23 KER31628.1 - 0.00079 19.4 0.1 0.72 9.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ig PF00047.25 KER31628.1 - 0.0095 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Kinase-like PF14531.6 KER31628.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ig_2 PF13895.6 KER31628.1 - 0.027 14.8 0.2 0.064 13.6 0.2 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LIM PF00412.22 KER31629.1 - 3.9e-30 103.9 35.3 2.3e-12 46.9 6.2 3.4 3 0 0 3 3 3 3 LIM domain PDZ PF00595.24 KER31629.1 - 8.2e-13 48.5 0.1 1.3e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER31629.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER31629.1 - 0.003 17.8 0.0 0.0076 16.6 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Auto_anti-p27 PF06677.12 KER31629.1 - 0.2 11.8 0.1 0.2 11.8 0.1 4.5 5 1 0 5 5 5 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) I-set PF07679.16 KER31631.1 - 2.7e-10 40.2 0.0 5.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KER31631.1 - 4.3e-10 39.6 0.1 1.5e-09 37.9 0.0 2.0 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.6 KER31631.1 - 2.3e-09 37.7 0.0 4.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.15 KER31631.1 - 1.8e-06 28.0 2.3 9.4e-06 25.7 2.3 2.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.18 KER31631.1 - 5.6e-06 26.9 16.9 5.6e-06 26.9 16.9 2.0 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Ig_2 PF13895.6 KER31631.1 - 7.8e-05 22.9 0.0 0.00026 21.3 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Kazal_1 PF00050.21 KER31631.1 - 0.00034 20.5 2.2 0.00034 20.5 2.2 2.2 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain V-set PF07686.17 KER31631.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Lentivirus_VIF PF05851.11 KER31631.1 - 0.27 10.1 2.3 0.36 9.7 2.3 1.1 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Ribul_P_3_epim PF00834.19 KER31634.1 - 8.8e-59 198.2 0.4 5.8e-58 195.6 0.4 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family DHHC PF01529.20 KER31634.1 - 1.2e-27 96.6 6.5 1.2e-27 96.6 6.5 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase QRPTase_C PF01729.19 KER31634.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Yip1 PF04893.17 KER31634.1 - 2 8.1 10.5 1.5 8.5 6.2 2.4 2 1 0 2 2 2 0 Yip1 domain EF-hand_6 PF13405.6 KER31635.1 - 7.3e-06 25.5 0.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 KER31635.1 - 0.00025 21.3 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KER31635.1 - 0.00026 21.4 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KER31635.1 - 0.00063 19.5 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair KASH PF10541.9 KER31635.1 - 0.084 13.1 0.0 23 5.3 0.0 2.4 2 0 0 2 2 2 0 Nuclear envelope localisation domain fn3 PF00041.21 KER31638.1 - 4.1e-13 49.5 2.2 0.021 15.2 0.5 5.9 4 2 1 5 5 5 3 Fibronectin type III domain EF-hand_7 PF13499.6 KER31638.1 - 2.3e-11 44.0 0.0 0.023 15.2 0.0 5.9 4 1 2 6 6 6 2 EF-hand domain pair EF-hand_9 PF14658.6 KER31638.1 - 3.9e-10 39.9 0.0 0.083 13.2 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain WAP PF00095.21 KER31638.1 - 3.4e-09 36.9 9.0 7.7e-09 35.8 9.0 1.7 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' EF-hand_6 PF13405.6 KER31638.1 - 2.5e-07 30.1 0.7 0.47 10.5 0.0 7.2 9 0 0 9 9 9 1 EF-hand domain GPHH PF16905.5 KER31638.1 - 3.8e-06 26.5 0.0 26 4.7 0.0 5.4 5 0 0 5 5 5 0 Voltage-dependent L-type calcium channel, IQ-associated Interfer-bind PF09294.10 KER31638.1 - 0.00052 20.3 0.1 0.74 10.2 0.0 3.4 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KER31638.1 - 0.0054 17.3 0.0 34 5.1 0.1 4.0 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain MHC_II_beta PF00969.19 KER31638.1 - 0.14 12.3 0.0 59 3.9 0.0 3.2 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Lactamase_B_3 PF13483.6 KER31638.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain EF-hand_7 PF13499.6 KER31639.1 - 5.6e-07 29.9 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER31639.1 - 2.7e-05 23.7 0.0 0.055 13.4 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 KER31639.1 - 3e-05 24.2 0.0 0.00021 21.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KER31639.1 - 0.00019 21.2 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER31639.1 - 0.0048 16.3 0.0 0.29 10.8 0.0 3.4 5 0 0 5 5 5 1 EF hand PTS_2-RNA PF01885.16 KER31640.1 - 2.4e-58 197.1 0.0 3.4e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Utp11 PF03998.13 KER31641.1 - 0.00015 21.8 1.7 0.0002 21.4 1.7 1.1 1 0 0 1 1 1 1 Utp11 protein SKA1 PF07160.12 KER31641.1 - 0.00033 20.6 1.7 0.00046 20.1 1.7 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF2076 PF09849.9 KER31641.1 - 0.0016 18.5 0.7 0.0021 18.1 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF4618 PF15397.6 KER31641.1 - 0.0083 15.6 0.5 0.011 15.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF3450 PF11932.8 KER31641.1 - 0.012 15.0 0.9 0.018 14.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Noelin-1 PF12308.8 KER31641.1 - 0.051 13.6 0.5 0.051 13.6 0.5 1.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein TSC22 PF01166.18 KER31641.1 - 0.11 12.8 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2681 PF10883.8 KER31641.1 - 0.16 12.4 2.0 0.33 11.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Csm1_N PF18504.1 KER31641.1 - 0.29 11.5 3.2 0.5 10.8 3.2 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain Glycos_transf_2 PF00535.26 KER31642.1 - 1.6e-24 86.6 0.0 2.2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KER31642.1 - 9.6e-11 42.0 0.0 1.6e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KER31642.1 - 0.00015 21.4 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Acyltransferase PF01553.21 KER31643.1 - 2e-11 43.6 0.0 3.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MFS_1_like PF12832.7 KER31644.1 - 1.2e-85 287.7 6.3 1.5e-85 287.4 6.3 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KER31644.1 - 1.4e-25 90.0 18.4 3.7e-13 49.1 15.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KER31644.1 - 3.1e-08 32.6 14.0 0.0015 17.1 0.3 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein LacY_symp PF01306.19 KER31644.1 - 1.6e-07 30.5 19.1 0.0051 15.6 4.0 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter Nuc_H_symport PF03825.16 KER31644.1 - 7.2e-07 28.5 19.9 2.8e-06 26.6 6.2 3.1 3 0 0 3 3 3 2 Nucleoside H+ symporter MFS_3 PF05977.13 KER31644.1 - 0.082 11.3 3.1 0.051 12.0 0.6 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector zf-C3HC4_2 PF13923.6 KER31645.1 - 1.3e-10 41.0 7.1 2.8e-10 39.8 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER31645.1 - 6e-08 32.4 6.5 1.6e-07 31.1 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER31645.1 - 7.2e-07 29.4 6.9 7.2e-07 29.4 6.9 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER31645.1 - 4.5e-06 26.4 5.8 4.5e-06 26.4 5.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER31645.1 - 5e-06 26.7 2.5 1.4e-05 25.2 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KER31645.1 - 2.3e-05 24.2 10.2 4.6e-05 23.3 9.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KER31645.1 - 0.00071 19.4 12.2 0.0032 17.3 10.3 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KER31645.1 - 0.0053 16.9 7.9 0.016 15.4 7.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RAWUL PF16207.5 KER31645.1 - 0.0078 16.9 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 KER31645.1 - 0.011 15.8 5.8 0.011 15.8 5.8 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.8 KER31645.1 - 0.011 15.5 2.5 0.024 14.4 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KER31645.1 - 0.021 14.7 4.7 0.043 13.7 4.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KER31645.1 - 0.1 12.7 2.1 0.22 11.6 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KER31645.1 - 0.12 12.4 2.1 0.33 11.0 2.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 KER31645.1 - 0.3 11.3 5.9 0.93 9.7 5.9 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KER31645.1 - 0.3 10.9 6.2 0.046 13.5 1.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2620 PF10941.8 KER31646.1 - 0.042 14.0 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF2620 ASH PF15780.5 KER31648.1 - 1e-10 41.6 4.3 0.03 14.5 0.0 7.2 8 0 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 KER31648.1 - 8.3e-05 22.8 0.2 3.4 8.0 0.0 5.7 6 0 0 6 6 6 2 Transmembrane protein 131-like MYCBPAP PF14646.6 KER31648.1 - 0.0076 15.2 0.1 2.2 7.1 0.1 2.8 2 0 0 2 2 2 2 MYCBP-associated protein family PapD-like PF14874.6 KER31648.1 - 0.056 13.6 0.0 60 3.9 0.0 4.6 5 0 0 5 5 5 0 Flagellar-associated PapD-like fn3_5 PF06280.12 KER31648.1 - 0.12 13.0 0.1 61 4.3 0.0 3.5 4 0 0 4 4 4 0 Fn3-like domain Glycolytic PF00274.19 KER31649.1 - 1.9e-182 605.7 0.0 2.1e-182 605.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I LRR_6 PF13516.6 KER31650.1 - 3.5e-09 36.0 3.6 0.086 12.9 0.0 4.8 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 KER31650.1 - 0.062 13.7 0.0 18 5.9 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER31650.1 - 0.43 11.3 1.6 81 4.4 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat Med3 PF11593.8 KER31651.1 - 0.088 12.0 0.4 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.12 KER31651.1 - 1.9 6.4 3.1 2.3 6.1 3.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2 PF00096.26 KER31653.1 - 2.3e-17 62.4 67.6 0.00024 21.4 0.9 9.7 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31653.1 - 1.3e-14 53.6 55.6 0.00057 20.5 0.5 9.6 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31653.1 - 1.6e-11 44.1 57.4 8.3e-05 22.8 2.4 9.2 9 0 0 9 9 9 6 Zinc-finger double domain zf-met PF12874.7 KER31653.1 - 1.1e-06 28.8 24.8 0.0039 17.5 1.0 7.2 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KER31653.1 - 0.0001 22.0 2.8 0.0001 22.0 2.8 6.7 6 0 0 6 6 6 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KER31653.1 - 0.00023 21.1 27.8 0.0083 16.1 0.4 6.1 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER31653.1 - 0.096 13.0 29.7 0.27 11.6 0.4 7.0 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding ABC2_membrane_3 PF12698.7 KER31653.1 - 0.31 10.1 0.4 0.56 9.3 0.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Actin_micro PF17003.5 KER31653.1 - 0.56 9.3 8.2 5.7 6.0 3.9 3.2 1 1 0 2 2 2 0 Putative actin-like family YL1 PF05764.13 KER31653.1 - 1.9 8.5 23.0 0.5 10.4 8.5 3.3 3 0 0 3 3 3 0 YL1 nuclear protein ADK_lid PF05191.14 KER31653.1 - 2.8 8.0 14.1 0.64 10.1 2.3 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid DUF4807 PF16065.5 KER31654.1 - 3.2e-38 130.2 0.0 3.8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) BTB_2 PF02214.22 KER31657.1 - 1.9e-17 63.4 0.1 4.8e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KER31657.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ERp29 PF07749.12 KER31658.1 - 3e-13 50.5 0.0 4.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain zf-CCCH PF00642.24 KER31659.1 - 1.7e-15 56.4 12.2 2.3e-08 33.7 2.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KER31659.1 - 1.6e-06 27.7 19.6 4.3e-05 23.2 1.8 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KER31659.1 - 0.00056 19.9 21.1 0.011 15.8 1.7 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KER31659.1 - 0.0013 19.1 11.7 0.057 13.9 0.2 3.3 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger PP1_bind PF15276.6 KER31661.1 - 1.4e-11 44.5 8.0 5e-11 42.8 2.5 5.3 2 1 0 2 2 2 1 Protein phosphatase 1 binding Albumin_I_a PF16720.5 KER31662.1 - 1.6e-12 47.1 11.4 39 4.3 0.0 10.2 10 0 0 10 10 10 10 Albumin I chain a ABC2_membrane_3 PF12698.7 KER31662.1 - 2.4e-10 40.1 0.1 46 3.0 0.0 9.1 10 0 0 10 10 10 8 ABC-2 family transporter protein Astacin PF01400.24 KER31662.1 - 7.6 6.1 51.5 20 4.7 0.5 9.8 10 0 0 10 10 10 0 Astacin (Peptidase family M12A) DUF4486 PF14858.6 KER31664.1 - 0.055 11.9 0.1 0.06 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) TPR_8 PF13181.6 KER31664.1 - 0.073 13.3 0.4 0.15 12.4 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31664.1 - 0.085 13.5 0.2 0.19 12.4 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YgbB PF02542.16 KER31664.1 - 0.15 12.4 0.0 0.17 12.2 0.0 1.0 1 0 0 1 1 1 0 YgbB family Ribosomal_L37 PF08561.10 KER31665.1 - 1.5e-05 25.5 0.3 2.7e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 YcbB PF08664.10 KER31665.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 YcbB domain zf-NOSIP PF15906.5 KER31665.1 - 0.098 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein RVT_1 PF00078.27 KER31666.1 - 3.1e-14 53.0 0.0 4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIRS_C PF02769.22 KER31666.1 - 0.0005 20.2 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS_C PF02769.22 KER31667.1 - 1.7e-13 51.0 0.0 2.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain E3_UFM1_ligase PF09743.9 KER31669.1 - 4.6e-86 288.8 0.0 8.3e-86 288.0 0.0 1.4 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 KER31669.1 - 0.017 15.2 0.0 7.5 6.7 0.0 3.3 4 0 0 4 4 4 0 FeoC like transcriptional regulator zf-C2H2_assoc PF16606.5 KER31670.1 - 0.068 13.4 2.2 0.19 12.0 2.2 1.8 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers SPC22 PF04573.12 KER31671.1 - 3.1e-46 157.0 0.5 3.3e-46 156.9 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Usp PF00582.26 KER31672.1 - 1.8e-06 28.5 0.0 0.00012 22.6 0.0 2.0 1 1 1 2 2 2 2 Universal stress protein family DUF287 PF03384.14 KER31672.1 - 0.077 13.4 0.1 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 YfaZ PF07437.11 KER31672.1 - 0.11 12.1 0.0 13 5.4 0.0 2.1 1 1 1 2 2 2 0 YfaZ precursor EF-hand_1 PF00036.32 KER31673.1 - 3.3e-17 60.7 4.1 6.4e-07 28.5 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KER31673.1 - 1.2e-14 52.9 3.2 7.8e-06 25.4 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KER31673.1 - 2.7e-13 50.2 1.4 1.5e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KER31673.1 - 5.1e-08 32.7 6.8 0.0062 16.4 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KER31673.1 - 4.6e-06 26.9 0.0 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KER31673.1 - 0.00085 19.2 0.8 0.44 10.5 0.1 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 KER31673.1 - 0.0028 17.1 1.1 0.061 12.8 0.2 3.1 3 0 0 3 3 3 1 EF hand FlgD PF03963.14 KER31673.1 - 0.013 15.8 1.0 0.028 14.7 1.0 1.6 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region Staphylokinase PF02821.16 KER31673.1 - 0.013 15.9 0.6 0.026 15.0 0.1 1.7 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family TerB PF05099.13 KER31673.1 - 0.023 14.6 0.2 0.11 12.5 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Usp PF00582.26 KER31674.1 - 0.019 15.5 0.0 0.021 15.4 0.0 1.0 1 0 0 1 1 1 0 Universal stress protein family Synapsin PF02078.16 KER31674.1 - 0.03 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Synapsin, N-terminal domain AHJR-like PF18743.1 KER31674.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like DUF3156 PF11354.8 KER31675.1 - 0.0017 18.3 0.3 0.24 11.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3156) GTP-bdg_N PF13167.6 KER31675.1 - 0.0045 17.6 0.4 4.7 8.0 0.0 2.4 2 0 0 2 2 2 2 GTP-binding GTPase N-terminal Hemerythrin PF01814.23 KER31675.1 - 0.027 15.1 0.0 13 6.4 0.0 2.6 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Usp PF00582.26 KER31675.1 - 0.029 14.9 0.0 9.8 6.7 0.0 2.1 1 1 1 2 2 2 0 Universal stress protein family Synapsin PF02078.16 KER31675.1 - 0.031 14.5 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Synapsin, N-terminal domain DUF247 PF03140.15 KER31675.1 - 0.043 13.0 2.0 3.2 6.9 0.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function Peptidase_U57 PF05582.12 KER31675.1 - 0.045 13.0 0.5 4.1 6.6 0.2 2.2 2 0 0 2 2 2 0 YabG peptidase U57 Pox_A22 PF04848.13 KER31675.1 - 0.056 13.6 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A22 protein DBINO PF13892.6 KER31675.1 - 0.071 13.5 3.5 2.6 8.4 0.8 2.8 2 2 0 2 2 2 0 DNA-binding domain HEPN_Apea PF18739.1 KER31675.1 - 0.097 13.1 0.2 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Apea-like HEPN DUF4254 PF14063.6 KER31675.1 - 0.17 11.7 2.1 7 6.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) Usp PF00582.26 KER31677.1 - 0.0023 18.4 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Hydrolase_2 PF07486.12 KER31677.1 - 0.17 12.7 0.0 0.75 10.7 0.0 1.9 2 0 0 2 2 2 0 Cell Wall Hydrolase Usp PF00582.26 KER31678.1 - 4.8e-16 59.5 0.0 9.9e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 KER31679.1 - 1.1e-13 51.9 0.0 2.4e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family SurE PF01975.17 KER31679.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Survival protein SurE Homeodomain PF00046.29 KER31680.1 - 5.5e-06 26.1 3.6 0.0016 18.3 1.5 2.7 2 0 0 2 2 2 2 Homeodomain VWA_N2 PF16164.5 KER31680.1 - 0.057 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 VWA N-terminal YdaS_antitoxin PF15943.5 KER31680.1 - 0.22 11.4 0.5 0.54 10.2 0.2 1.8 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CAP_GLY PF01302.25 KER31681.1 - 5.7e-20 71.1 0.0 9.8e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain PAC1 PF16094.5 KER31684.1 - 5.6e-14 52.0 0.0 9.1e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Myotub-related PF06602.14 KER31685.1 - 1.2e-63 215.2 0.0 1.4e-62 211.7 0.0 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain DENN PF02141.21 KER31685.1 - 1.1e-43 149.4 0.2 3.7e-43 147.6 0.2 2.0 1 0 0 1 1 1 1 DENN (AEX-3) domain SBF2 PF12335.8 KER31685.1 - 2.6e-35 122.1 7.1 7.8e-31 107.5 0.5 2.9 2 1 1 3 3 3 2 Myotubularin protein PH PF00169.29 KER31685.1 - 9.2e-14 51.8 0.0 1.9e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 PH domain uDENN PF03456.18 KER31685.1 - 7e-12 45.9 0.8 7e-12 45.9 0.8 2.9 3 0 0 3 3 3 1 uDENN domain C1_1 PF00130.22 KER31685.1 - 2.9e-08 33.4 11.7 7.2e-08 32.2 10.6 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) GRAM PF02893.20 KER31685.1 - 2.5e-06 27.4 0.0 6.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 GRAM domain PH_8 PF15409.6 KER31685.1 - 2.6e-06 27.6 0.4 9.2e-06 25.9 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KER31685.1 - 0.0042 17.5 1.8 0.019 15.4 0.5 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KER31685.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ras PF00071.22 KER31688.1 - 1.4e-37 128.8 0.0 1.2e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KER31688.1 - 1.7e-13 50.8 0.0 1.1e-05 25.6 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KER31688.1 - 8.2e-06 25.8 0.0 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 KER31688.1 - 1.7e-05 24.3 0.0 0.0086 15.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER31688.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-C2H2_11 PF16622.5 KER31689.1 - 0.0058 16.4 1.0 0.0058 16.4 1.0 4.4 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 KER31689.1 - 0.0081 16.6 46.9 0.74 10.4 0.3 8.7 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31689.1 - 0.055 14.3 0.6 0.055 14.3 0.6 9.5 9 0 0 9 9 9 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER31689.1 - 0.064 13.7 0.5 0.064 13.7 0.5 5.8 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2HE PF16278.5 KER31689.1 - 0.11 12.9 17.1 7.1 7.2 0.1 5.3 4 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KER31689.1 - 0.75 10.1 18.0 0.46 10.8 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KER31689.1 - 0.98 9.8 22.2 0.15 12.3 0.2 4.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KER31689.1 - 7.9 6.5 8.1 1.7 8.6 0.0 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 KER31689.1 - 9.2 7.0 15.2 0.21 12.2 2.1 4.2 4 0 0 4 4 4 0 FOXP coiled-coil domain DUF3767 PF12597.8 KER31690.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) CDO_I PF05995.12 KER31692.1 - 1.7e-49 167.4 0.0 2.2e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KER31692.1 - 0.00064 19.2 0.0 0.0018 17.8 0.0 1.6 2 1 0 2 2 2 1 PCO_ADO fn3 PF00041.21 KER31694.1 - 8.6e-15 54.9 0.2 5.6e-08 33.0 0.0 4.1 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER31694.1 - 0.011 16.3 0.0 6.9 7.3 0.1 3.0 2 2 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KER31695.1 - 0.00068 19.9 0.0 0.077 13.4 0.0 2.9 2 1 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.21 KER31696.1 - 6.3e-22 77.7 6.7 3.2e-08 33.8 0.2 4.0 3 1 0 3 3 3 3 Fibronectin type III domain Arylsulfotran_N PF17425.2 KER31696.1 - 0.0082 16.2 0.7 0.022 14.8 0.3 1.8 2 0 0 2 2 2 1 Arylsulfotransferase Ig-like domain Pur_ac_phosph_N PF16656.5 KER31696.1 - 0.022 15.3 2.2 0.19 12.3 0.1 3.0 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain GPI-anchored PF10342.9 KER31696.1 - 0.051 14.3 1.4 0.5 11.2 0.1 2.9 3 1 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Interfer-bind PF09294.10 KER31696.1 - 0.1 13.0 0.0 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III RT_RNaseH_2 PF17919.1 KER31697.1 - 9.7e-09 35.2 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER31697.1 - 8e-08 32.5 0.0 9.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Adeno_E3_CR2 PF02439.15 KER31699.1 - 0.13 12.1 2.5 0.3 10.9 2.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_6 PF13516.6 KER31701.1 - 9.2e-10 37.8 1.4 3.6e-05 23.5 0.1 3.4 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 KER31701.1 - 1.2e-05 25.2 0.0 0.44 11.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat DUF1964 PF09244.10 KER31704.1 - 0.042 14.3 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1964) Metallophos_2 PF12850.7 KER31706.1 - 0.083 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PH PF00169.29 KER31707.1 - 6.7e-07 29.8 0.5 2.2e-06 28.1 0.5 1.8 1 1 0 1 1 1 1 PH domain 2-oxoacid_dh PF00198.23 KER31709.1 - 2.6e-75 252.8 0.0 3.2e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 KER31709.1 - 2e-10 40.8 0.2 9.8e-10 38.6 0.1 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.22 KER31709.1 - 3.7e-09 36.3 0.9 7.2e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Keratin_2_head PF16208.5 KER31710.1 - 0.085 13.0 6.2 0.12 12.5 6.2 1.1 1 0 0 1 1 1 0 Keratin type II head KH_1 PF00013.29 KER31712.1 - 9.3e-23 79.8 2.0 2.9e-12 46.2 0.6 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KER31712.1 - 1.3e-12 47.3 0.7 1.9e-06 27.6 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KER31712.1 - 0.00032 20.5 0.3 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KER31712.1 - 0.0022 18.0 0.6 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 NusA-like KH domain Vps53_N PF04100.12 KER31713.1 - 4.9e-88 295.6 7.8 2.5e-51 174.8 0.1 2.2 2 0 0 2 2 2 2 Vps53-like, N-terminal AAA_13 PF13166.6 KER31713.1 - 0.0027 16.4 1.7 0.0054 15.4 1.7 1.4 1 0 0 1 1 1 1 AAA domain Tropomyosin PF00261.20 KER31713.1 - 0.014 14.7 1.8 0.029 13.7 1.8 1.4 1 0 0 1 1 1 0 Tropomyosin DUF932 PF06067.11 KER31713.1 - 0.14 11.9 1.1 0.3 10.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Vps54_N PF10475.9 KER31713.1 - 0.3 10.3 7.4 0.14 11.4 2.7 2.6 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex XhlA PF10779.9 KER31713.1 - 1.1 9.5 4.3 3 8.1 0.9 2.7 2 0 0 2 2 2 0 Haemolysin XhlA COG5 PF10392.9 KER31713.1 - 1.3 9.2 7.5 0.46 10.7 2.2 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 KER31713.1 - 9.1 6.3 7.0 2.6e+02 1.7 6.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 KER31714.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.28 KER31716.1 - 6.2e-92 308.4 0.0 8.2e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER31716.1 - 0.027 15.5 0.0 0.064 14.2 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SOCS_box PF07525.16 KER31717.1 - 3.9e-05 23.9 3.9 3.9e-05 23.9 3.9 2.1 2 0 0 2 2 2 1 SOCS box Ank_4 PF13637.6 KER31717.1 - 0.019 15.5 0.0 0.056 14.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SGT1 PF07093.11 KER31718.1 - 4.4e-76 256.6 1.4 4.5e-46 157.5 0.2 2.6 2 1 0 3 3 3 2 SGT1 protein zf-LITAF-like PF10601.9 KER31719.1 - 2.7e-18 66.0 16.8 4.1e-18 65.4 16.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain RabGAP-TBC PF00566.18 KER31720.1 - 2.9e-22 79.4 0.1 4e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain VCBS PF13517.6 KER31720.1 - 2.8e-12 47.0 12.8 0.0013 19.3 0.0 5.5 4 1 2 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KER31720.1 - 5.9e-05 23.1 22.3 0.38 10.9 0.1 6.1 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 KER31720.1 - 0.016 14.6 2.3 2.2 7.6 0.0 3.4 2 1 2 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region MMPL PF03176.15 KER31721.1 - 0.16 10.9 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 MMPL family Glyco_transf_25 PF01755.17 KER31722.1 - 3.8e-26 92.2 0.0 1e-24 87.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 KER31722.1 - 5.1e-06 26.9 1.1 1.6e-05 25.3 1.1 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 KER31722.1 - 0.00089 19.1 0.0 5.9 6.7 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KER31722.1 - 0.074 12.5 0.0 5 6.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Anp1 PF03452.14 KER31722.1 - 0.13 11.7 0.9 1.3 8.4 0.9 2.1 1 1 0 1 1 1 0 Anp1 NTP_transf_3 PF12804.7 KER31722.1 - 0.17 12.3 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain MoaE PF02391.17 KER31723.1 - 8.7e-36 122.6 0.0 1e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein RVT_1 PF00078.27 KER31724.1 - 4.6e-18 65.6 0.0 7.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 KER31724.1 - 5e-05 24.1 6.8 8.3e-05 23.4 4.1 2.5 2 1 0 2 2 2 1 Cysteine-rich secretory protein family NitrOD5 PF11537.8 KER31724.1 - 0.055 13.6 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Nitrosopumilus output domain 5 DUF824 PF05688.11 KER31724.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Cdh1_DBD_1 PF18196.1 KER31724.1 - 0.1 12.9 0.1 2 8.8 0.0 2.2 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 CAP PF00188.26 KER31725.1 - 3.3e-13 50.6 0.0 3e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family TIR_2 PF13676.6 KER31727.1 - 1.5e-10 41.7 0.0 7.6e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 TIR domain DUF5578 PF17741.1 KER31728.1 - 4.7e-123 409.9 1.6 6.4e-123 409.4 1.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) TIR_2 PF13676.6 KER31730.1 - 1.5e-05 25.6 0.0 7.7e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 TIR domain RCC1_2 PF13540.6 KER31731.1 - 3.3e-31 106.4 15.6 4e-09 36.1 0.5 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KER31731.1 - 3.1e-21 75.7 14.9 6.4e-10 39.5 0.0 5.0 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PI3_PI4_kinase PF00454.27 KER31732.1 - 2.7e-48 165.0 0.0 7.9e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KER31732.1 - 4.5e-25 88.6 0.8 8e-25 87.8 0.8 1.4 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KER31732.1 - 5.5e-16 58.1 0.0 2.3e-15 56.1 0.0 2.2 1 0 0 1 1 1 1 FATC domain UME PF08064.13 KER31732.1 - 8.7e-13 48.1 0.1 3.3e-12 46.2 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain DUF4042 PF13251.6 KER31732.1 - 0.087 12.5 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) ubiquitin PF00240.23 KER31734.1 - 1.4e-17 63.1 0.0 3.3e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 KER31734.1 - 2.3e-08 34.1 7.3 5e-08 33.0 7.3 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 KER31734.1 - 3.6e-06 26.7 0.0 7.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KER31734.1 - 0.0082 16.6 0.2 0.036 14.5 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain DUF3740 PF12548.8 KER31734.1 - 0.037 14.5 1.9 0.081 13.4 1.9 1.6 1 0 0 1 1 1 0 Sulfatase protein Jnk-SapK_ap_N PF09744.9 KER31734.1 - 0.22 11.8 1.7 0.37 11.0 1.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LLC1 PF14945.6 KER31734.1 - 0.22 12.1 1.5 0.46 11.1 0.4 2.2 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MOLO1 PF17175.4 KER31736.1 - 5.6e-22 78.1 0.0 9.7e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 KER31736.1 - 0.0043 17.2 0.0 0.48 10.6 0.0 2.2 2 0 0 2 2 2 2 TPM domain UCR_hinge PF02320.16 KER31737.1 - 2.9e-15 56.2 1.0 4.1e-15 55.7 1.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 KER31737.1 - 0.029 14.5 3.0 0.08 13.1 0.1 2.2 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 KER31737.1 - 0.16 12.0 3.7 5.1 7.2 3.9 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NUC194 PF08163.12 KER31738.1 - 1.6e-35 122.8 0.0 6.5e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 NUC194 domain PI3_PI4_kinase PF00454.27 KER31738.1 - 0.0011 18.8 0.0 0.0035 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase gag_pre-integrs PF13976.6 KER31738.1 - 0.18 11.7 1.3 3.6 7.5 0.0 3.4 4 0 0 4 4 4 0 GAG-pre-integrase domain PKD PF00801.20 KER31740.1 - 1.5e-23 82.4 11.3 1.1e-09 37.9 0.0 7.7 7 0 0 7 7 7 4 PKD domain PKD_3 PF16820.5 KER31740.1 - 0.00031 20.4 1.5 0.22 11.3 0.1 5.0 5 0 0 5 5 5 1 PKD-like domain WSC PF01822.19 KER31740.1 - 0.00068 19.8 2.5 0.00068 19.8 2.5 2.6 2 0 0 2 2 2 1 WSC domain Arrestin_C PF02752.22 KER31740.1 - 0.035 14.6 1.2 5.9 7.3 0.0 4.1 4 0 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain PKD_channel PF08016.12 KER31741.1 - 2.6e-89 299.9 15.0 2.6e-89 299.9 15.0 1.9 2 0 0 2 2 2 1 Polycystin cation channel PLAT PF01477.23 KER31741.1 - 2.4e-19 70.0 0.0 6.7e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 PLAT/LH2 domain Ion_trans PF00520.31 KER31741.1 - 2e-11 43.6 26.6 2e-11 43.6 26.6 3.0 4 0 0 4 4 4 1 Ion transport protein GPS PF01825.21 KER31741.1 - 1.9e-06 28.3 5.5 4.6e-06 27.1 5.5 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Abhydrolase_9_N PF15420.6 KER31741.1 - 3.8 7.5 8.6 0.92 9.5 3.6 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Tubulin PF00091.25 KER31743.1 - 9e-69 231.6 0.0 1.5e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER31743.1 - 3.3e-42 143.6 0.1 5.4e-42 142.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER31743.1 - 5.5e-05 23.5 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KER31743.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 KER31743.1 - 0.042 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Ribosomal_L4 PF00573.22 KER31745.1 - 5e-31 107.9 0.0 2.1e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family RFC1 PF08519.12 KER31746.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain RFC1 PF08519.12 KER31747.1 - 2.4e-38 131.8 0.0 2.1e-37 128.7 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KER31747.1 - 1.7e-19 70.5 0.3 2e-14 54.1 0.0 3.3 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 KER31747.1 - 1.2e-12 48.1 0.0 4.1e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA_16 PF13191.6 KER31747.1 - 0.00041 20.8 0.0 0.037 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER31747.1 - 0.00046 20.5 0.2 0.012 15.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KER31747.1 - 0.0017 18.1 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER31747.1 - 0.0047 16.9 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PTCB-BRCT PF12738.7 KER31747.1 - 0.0094 15.9 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain RNA_helicase PF00910.22 KER31747.1 - 0.012 16.0 0.1 0.63 10.5 0.1 3.3 1 1 1 2 2 2 0 RNA helicase Rad17 PF03215.15 KER31747.1 - 0.012 15.5 0.2 0.93 9.4 0.1 2.8 2 1 0 2 2 2 0 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KER31747.1 - 0.013 15.3 0.4 0.058 13.2 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF2161 PF09929.9 KER31747.1 - 0.024 14.8 0.0 0.79 9.9 0.0 2.6 1 1 1 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) BRCT_2 PF16589.5 KER31747.1 - 0.091 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain AAA_33 PF13671.6 KER31747.1 - 0.13 12.4 0.0 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KER31747.1 - 0.13 11.5 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pro_CA PF00484.19 KER31749.1 - 1.8e-19 70.6 0.0 1.3e-17 64.5 0.0 2.1 1 1 0 1 1 1 1 Carbonic anhydrase ANAPC4_WD40 PF12894.7 KER31750.1 - 6.2e-10 39.3 3.1 0.023 15.0 0.1 5.0 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 KER31750.1 - 1.3e-05 25.1 1.9 0.00022 21.1 0.5 2.5 1 1 1 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 KER31750.1 - 0.012 16.5 3.2 2.7 9.0 0.0 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat VCBS PF13517.6 KER31751.1 - 0.001 19.6 0.7 0.14 12.8 0.1 2.8 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KER31751.1 - 0.028 14.5 0.2 0.028 14.5 0.2 1.9 2 0 0 2 2 2 0 FG-GAP repeat YL1 PF05764.13 KER31752.1 - 1.5 8.9 8.6 1.8 8.6 8.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BAALC_N PF06989.12 KER31759.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 BAALC N-terminus Ribosomal_S18 PF01084.20 KER31761.1 - 2.4e-12 46.9 0.2 6.4e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Palm_thioest PF02089.15 KER31761.1 - 0.21 11.4 0.0 14 5.4 0.0 2.1 1 1 1 2 2 2 0 Palmitoyl protein thioesterase RT_RNaseH_2 PF17919.1 KER31762.1 - 0.025 14.6 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 KER31763.1 - 2.8e-63 213.7 0.0 4.5e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31763.1 - 8.3e-36 123.6 0.0 4.3e-35 121.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KER31763.1 - 1.7e-12 47.5 0.0 5.1e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KER31763.1 - 8.3e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER31763.1 - 0.00024 20.0 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KER31763.1 - 0.061 12.3 2.0 0.13 11.2 0.2 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KER31763.1 - 0.22 11.4 0.1 3.1 7.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ion_trans PF00520.31 KER31766.1 - 1.7e-09 37.3 0.5 2.1e-09 37.0 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KER31767.1 - 2e-07 30.5 4.1 2.5e-07 30.2 4.1 1.1 1 0 0 1 1 1 1 Ion transport protein TUDOR PF00567.24 KER31769.1 - 1.9e-06 27.9 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Tudor domain DUF2177 PF09945.9 KER31769.1 - 0.13 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) ATP_bind_2 PF03668.15 KER31771.1 - 0.001 18.4 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 2 P-loop ATPase protein family Ig_3 PF13927.6 KER31772.1 - 2.6e-24 85.6 10.3 1.3e-06 28.8 0.3 7.5 6 2 0 6 6 6 4 Immunoglobulin domain C2-set_2 PF08205.12 KER31772.1 - 2.3e-14 53.2 14.2 4.7e-08 33.0 0.2 5.6 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain I-set PF07679.16 KER31772.1 - 4.9e-14 52.2 1.0 0.0026 17.8 0.1 6.9 5 2 0 5 5 5 2 Immunoglobulin I-set domain ig PF00047.25 KER31772.1 - 4.7e-13 49.1 18.6 0.0016 18.5 0.1 8.0 7 2 0 7 7 7 3 Immunoglobulin domain Ig_2 PF13895.6 KER31772.1 - 2.6e-12 46.9 3.6 1.1 9.6 0.0 8.2 8 0 0 8 8 8 3 Immunoglobulin domain V-set PF07686.17 KER31772.1 - 1.3e-11 44.6 3.7 0.019 15.1 0.3 7.5 7 1 0 7 7 7 2 Immunoglobulin V-set domain C1-set PF07654.15 KER31772.1 - 1.4e-05 25.4 1.5 1 9.8 0.0 5.5 5 0 0 5 5 5 1 Immunoglobulin C1-set domain UPF0730 PF15827.5 KER31772.1 - 0.057 13.2 0.6 0.22 11.3 0.6 2.0 1 0 0 1 1 1 0 UPF0730 unknown protein family GATA PF00320.27 KER31775.1 - 4e-17 61.5 18.8 5e-15 54.8 4.6 2.8 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KER31775.1 - 0.0065 16.0 8.0 0.16 11.5 1.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.10 KER31775.1 - 0.12 12.5 3.3 6.6 7.0 0.1 2.9 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Vps36-NZF-N PF16988.5 KER31775.1 - 0.28 10.6 2.5 1.5 8.2 0.3 3.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-B_box PF00643.24 KER31775.1 - 1.2 9.3 7.0 1 9.6 0.5 3.3 2 2 0 2 2 2 0 B-box zinc finger DZR PF12773.7 KER31775.1 - 1.3 9.1 8.7 3.4 7.8 0.3 3.3 3 1 0 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KER31775.1 - 1.3 9.0 7.3 1.5 8.8 1.0 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KER31775.1 - 1.4 9.1 6.3 2.8 8.1 0.2 3.2 2 1 1 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KER31775.1 - 3.9 7.4 6.2 4 7.3 1.0 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 A2L_zn_ribbon PF08792.10 KER31775.1 - 4 7.3 7.2 24 4.8 0.1 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain TSP_1 PF00090.19 KER31776.1 - 1.8e-06 28.0 7.3 1.8e-06 28.0 7.3 3.6 4 0 0 4 4 4 2 Thrombospondin type 1 domain PAAR_motif PF05488.13 KER31778.1 - 0.081 13.1 0.1 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 PAAR motif PI3_PI4_kinase PF00454.27 KER31780.1 - 3.2e-38 132.0 0.1 2.9e-37 128.8 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Toxin_16 PF07945.11 KER31780.1 - 0.096 12.6 5.4 0.19 11.7 5.4 1.4 1 0 0 1 1 1 0 Janus-atracotoxin LRR_adjacent PF08191.11 KER31781.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 LRR adjacent RNA_binding PF01877.17 KER31781.1 - 0.038 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding Pkinase PF00069.25 KER31782.1 - 1.2e-51 175.6 0.0 3.5e-51 174.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31782.1 - 1.2e-25 90.3 0.0 2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KER31782.1 - 2.1e-09 36.8 5.4 0.02 15.1 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KER31782.1 - 1.1e-05 25.8 1.2 1.1e-05 25.8 1.2 4.6 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KER31782.1 - 6.5e-05 23.2 3.8 0.00033 21.0 1.2 3.4 3 1 0 3 3 3 1 HEAT repeats Kinase-like PF14531.6 KER31782.1 - 0.00032 20.1 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SDA1 PF05285.12 KER31782.1 - 0.0046 16.4 34.4 0.0046 16.4 34.4 2.2 2 0 0 2 2 2 1 SDA1 Arm PF00514.23 KER31782.1 - 0.017 15.2 14.4 0.12 12.5 0.1 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Haspin_kinase PF12330.8 KER31782.1 - 0.044 12.7 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF4042 PF13251.6 KER31782.1 - 0.052 13.2 1.7 1 9.0 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) KH_1 PF00013.29 KER31783.1 - 7e-48 160.3 13.8 1.3e-17 63.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KER31783.1 - 4.8e-13 48.7 3.5 0.00087 19.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KER31783.1 - 5.3e-08 32.6 3.1 0.076 12.9 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KER31783.1 - 0.00042 20.3 7.3 0.29 11.3 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KER31783.1 - 0.014 15.3 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 KH-like RNA-binding domain WD40 PF00400.32 KER31784.1 - 1.4e-46 155.4 35.8 1.2e-07 32.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31784.1 - 2.7e-23 82.1 2.9 0.00058 20.1 0.1 6.7 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER31784.1 - 2e-10 40.2 0.7 0.043 12.8 0.0 5.1 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KER31784.1 - 2.1e-05 24.0 2.8 0.0018 17.7 2.7 3.2 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KER31784.1 - 0.17 11.9 1.8 0.69 9.9 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KER31784.1 - 0.23 10.7 0.0 5.2 6.3 0.0 2.5 3 1 0 3 3 3 0 WD40-like domain IKI3 PF04762.12 KER31784.1 - 2.3 6.1 5.0 4.4 5.2 0.3 3.0 1 1 3 4 4 4 0 IKI3 family Hexapep PF00132.24 KER31786.1 - 3.7e-20 70.8 24.4 1.4e-07 31.0 2.5 5.4 2 2 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KER31786.1 - 7.2e-16 57.6 13.3 5.8e-06 25.9 1.2 4.3 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KER31786.1 - 0.0053 15.0 1.5 0.22 9.6 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4954) Pentapeptide_3 PF13576.6 KER31786.1 - 0.03 14.5 0.4 16 5.8 0.0 2.8 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) zf-HC3 PF16827.5 KER31786.1 - 0.087 13.0 2.1 0.2 11.9 2.1 1.6 1 0 0 1 1 1 0 zinc-finger Fucokinase PF07959.12 KER31786.1 - 0.1 11.5 0.3 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase MALT1_Ig PF18703.1 KER31789.1 - 0.02 14.9 0.1 0.055 13.5 0.1 1.7 1 0 0 1 1 1 0 MALT1 Ig-like domain Hjc PF01870.18 KER31791.1 - 0.015 15.3 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) WD40 PF00400.32 KER31793.1 - 5.9e-07 30.1 3.8 0.37 11.7 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31793.1 - 5.7e-05 23.3 0.0 0.8 10.1 0.0 4.8 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5122 PF17164.4 KER31793.1 - 0.5 10.7 1.4 14 6.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller EF-hand_7 PF13499.6 KER31795.1 - 2.2e-24 85.7 7.7 8.3e-13 48.6 3.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KER31795.1 - 7.4e-24 81.5 11.2 3.7e-08 32.4 1.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KER31795.1 - 1.3e-19 68.4 7.6 6.5e-07 28.8 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KER31795.1 - 1.2e-16 60.3 9.1 2.7e-11 43.1 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KER31795.1 - 1.9e-13 50.5 0.1 2.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain RVT_1 PF00078.27 KER31795.1 - 2.5e-13 50.1 0.0 3.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_5 PF13202.6 KER31795.1 - 2.8e-08 32.9 9.2 0.0006 19.2 1.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KER31795.1 - 0.00053 19.9 0.9 0.43 10.6 0.4 2.6 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 KER31795.1 - 0.0072 16.6 0.5 2.3 8.6 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 KER31795.1 - 0.11 13.4 0.1 9.1 7.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain SUB1_ProdP9 PF18213.1 KER31795.1 - 0.14 12.0 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Yip1 PF04893.17 KER31796.1 - 6.3e-13 48.8 13.7 6.3e-13 48.8 13.7 1.9 1 1 1 2 2 2 1 Yip1 domain EF-hand_7 PF13499.6 KER31797.1 - 2.5e-06 27.8 0.2 6e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KER31797.1 - 5e-06 26.0 0.4 0.066 13.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER31797.1 - 6.3e-05 22.3 0.4 0.013 15.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER31797.1 - 0.016 15.1 0.3 0.54 10.1 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KER31797.1 - 0.094 12.3 1.2 6.9 6.4 0.1 2.6 2 0 0 2 2 2 0 EF hand Cwf_Cwc_15 PF04889.12 KER31798.1 - 9.3e-06 25.5 43.4 0.0012 18.6 22.5 2.3 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KER31798.1 - 0.0088 15.5 28.6 0.011 15.1 28.6 1.2 1 0 0 1 1 1 1 SDA1 Spc42p PF11544.8 KER31798.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.7 3 0 0 3 3 3 0 Spindle pole body component Spc42p PARP_reg PF02877.14 KER31798.1 - 0.61 10.2 3.1 0.29 11.2 0.7 1.7 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain FAM76 PF16046.5 KER31798.1 - 5.7 6.2 6.2 13 5.1 1.9 2.0 1 1 1 2 2 2 0 FAM76 protein Rad60-SLD_2 PF13881.6 KER31799.1 - 0.017 15.2 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cyclin_N PF00134.23 KER31800.1 - 0.00036 20.3 0.0 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Apidaecin PF00807.17 KER31801.1 - 0.052 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Apidaecin Ribosomal_L1 PF00687.21 KER31803.1 - 6.2e-27 94.7 0.0 1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mito_carr PF00153.27 KER31805.1 - 2e-47 159.1 2.1 2e-20 72.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein AAA_2 PF07724.14 KER31806.1 - 1.1e-40 139.5 0.0 2e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KER31806.1 - 5.7e-13 49.4 0.0 1.1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KER31806.1 - 2.5e-12 46.7 0.1 5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KER31806.1 - 3.4e-06 27.1 0.0 8.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KER31806.1 - 8.8e-05 22.0 0.2 0.043 13.2 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KER31806.1 - 0.00013 21.7 0.0 0.001 18.8 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 KER31806.1 - 0.00014 22.1 0.1 0.00068 19.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KER31806.1 - 0.00051 20.1 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KER31806.1 - 0.002 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KER31806.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KER31806.1 - 0.0079 15.9 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KER31806.1 - 0.0089 16.4 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KER31806.1 - 0.017 15.1 0.2 0.062 13.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 KER31806.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KER31806.1 - 0.027 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KER31806.1 - 0.065 13.0 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 KER31806.1 - 0.074 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KER31806.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KER31806.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinase-PPPase PF03618.14 KER31806.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase MCM PF00493.23 KER31806.1 - 0.19 10.8 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain PhoH PF02562.16 KER31806.1 - 0.21 11.0 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NPR2 PF06218.11 KER31806.1 - 0.22 10.2 0.0 0.41 9.3 0.0 1.3 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF1464 PF07318.12 KER31807.1 - 0.066 12.3 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) ST7 PF04184.12 KER31808.1 - 5.2e-221 734.8 3.9 6.4e-221 734.5 3.9 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 KER31808.1 - 1.3e-06 28.7 1.9 0.00051 20.5 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER31808.1 - 1.3e-05 25.6 5.4 3.5 8.7 0.1 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER31808.1 - 4.5e-05 23.9 7.2 0.00012 22.5 2.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 KER31808.1 - 0.00042 20.2 1.8 0.00097 19.0 1.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_16 PF13432.6 KER31808.1 - 0.0063 17.1 5.4 0.093 13.4 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KER31808.1 - 0.14 12.5 6.8 11 6.4 0.8 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER31808.1 - 0.17 12.1 0.0 0.17 12.1 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sld7_C PF18596.1 KER31808.1 - 0.19 11.9 1.0 0.42 10.8 0.8 1.6 1 1 0 1 1 1 0 Sld7 C-terminal domain TPR_1 PF00515.28 KER31808.1 - 0.64 9.9 7.9 3.6 7.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RGS PF00615.19 KER31810.1 - 6.2e-27 94.2 1.7 1.1e-26 93.4 1.7 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PDZ_6 PF17820.1 KER31810.1 - 6.7e-10 38.7 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER31810.1 - 1.9e-08 34.6 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER31810.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RGS-like PF09128.11 KER31810.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Homeobox_KN PF05920.11 KER31811.1 - 0.17 11.8 0.1 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Homeobox KN domain zf-C3HC4 PF00097.25 KER31812.1 - 2.9e-09 36.6 12.2 2.9e-09 36.6 12.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER31812.1 - 3.5e-09 36.3 18.1 9e-09 35.0 12.2 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER31812.1 - 1.1e-08 34.8 8.6 1.1e-08 34.8 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER31812.1 - 5.2e-08 32.8 10.5 5.2e-08 32.8 10.5 3.2 4 0 0 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KER31812.1 - 9.6e-07 28.6 11.3 2.3e-06 27.4 9.2 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 BRCT PF00533.26 KER31812.1 - 1.2e-06 28.8 0.0 8.1e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RING_2 PF13639.6 KER31812.1 - 4.1e-06 27.0 11.2 4.1e-06 27.0 11.2 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KER31812.1 - 5.6e-06 26.4 10.0 5.6e-06 26.4 10.0 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KER31812.1 - 5.7e-06 26.2 13.9 1.6e-05 24.8 10.9 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 KER31812.1 - 0.00033 20.4 13.1 0.0014 18.4 9.2 3.5 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit BRCT_2 PF16589.5 KER31812.1 - 0.0019 18.5 0.0 0.027 14.9 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KER31812.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_6 PF14835.6 KER31812.1 - 0.013 15.3 3.2 0.043 13.7 3.2 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KER31812.1 - 0.034 14.0 8.4 0.17 11.7 8.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KER31812.1 - 0.036 14.4 7.9 0.16 12.3 7.9 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KER31812.1 - 0.14 12.2 3.1 0.55 10.3 3.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2225 PF09986.9 KER31812.1 - 0.15 11.8 1.2 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Rad50_zn_hook PF04423.14 KER31812.1 - 0.2 11.5 1.7 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif PSK_trans_fac PF07704.11 KER31812.1 - 0.23 12.2 3.2 2 9.2 0.9 2.7 2 0 0 2 2 2 0 Rv0623-like transcription factor zf-RING_11 PF17123.5 KER31812.1 - 0.81 9.5 8.1 2.5 7.9 8.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 KER31812.1 - 3.1 7.9 6.9 54 3.9 5.4 3.3 2 1 0 2 2 2 0 zinc-ribbons zf-Di19 PF05605.12 KER31812.1 - 7.9 6.9 13.2 6.7 7.1 7.2 3.3 3 1 0 3 3 1 0 Drought induced 19 protein (Di19), zinc-binding Beta-Casp PF10996.8 KER31814.1 - 9.5e-27 93.5 0.0 2.1e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KER31814.1 - 8.5e-19 67.2 0.0 1.6e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KER31814.1 - 5.8e-18 65.0 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KER31814.1 - 8.5e-08 32.4 0.2 0.00046 20.3 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KER31814.1 - 1.4e-07 31.3 0.1 1.7e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KER31814.1 - 0.053 13.4 0.0 0.59 10.0 0.0 2.5 2 1 0 2 2 2 0 Beta-lactamase superfamily domain MCM PF00493.23 KER31815.1 - 7.4e-56 188.7 0.0 1.5e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KER31815.1 - 4.6e-15 55.8 0.0 8.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KER31815.1 - 2.7e-06 26.9 0.1 0.0029 17.0 0.1 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KER31815.1 - 3.3e-05 23.9 0.0 6.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KER31815.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER31815.1 - 0.0064 16.9 1.2 0.036 14.4 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 KER31815.1 - 0.013 15.2 0.0 0.19 11.4 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KER31815.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_MalT PF17874.1 KER31816.1 - 9.3e-05 21.9 0.3 0.00074 19.0 0.0 2.4 3 0 0 3 3 3 1 MalT-like TPR region TAN PF11640.8 KER31816.1 - 0.16 12.1 3.2 0.38 10.9 0.3 3.0 3 1 0 3 3 3 0 Telomere-length maintenance and DNA damage repair AAA_10 PF12846.7 KER31820.1 - 0.0011 18.0 0.3 0.0013 17.8 0.3 1.1 1 0 0 1 1 1 1 AAA-like domain Rep_N PF08724.10 KER31820.1 - 0.012 15.4 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 Rep protein catalytic domain like SNF2_N PF00176.23 KER31822.1 - 3.3e-49 167.5 0.2 9.1e-49 166.0 0.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KER31822.1 - 3.6e-08 33.6 0.0 0.0017 18.4 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PCI PF01399.27 KER31824.1 - 3.8e-08 33.8 5.7 8.2e-08 32.7 2.1 3.3 2 1 1 3 3 3 1 PCI domain DIM1 PF02966.16 KER31830.1 - 8.1e-66 219.8 0.1 9.9e-66 219.5 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KER31830.1 - 9.3e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KER31830.1 - 0.048 14.0 0.2 0.075 13.4 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.15 KER31830.1 - 0.061 13.3 0.2 0.099 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KER31830.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TSC22 PF01166.18 KER31832.1 - 0.037 14.3 0.2 0.077 13.3 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family 7tm_1 PF00001.21 KER31833.1 - 2e-10 40.4 0.4 3.2e-10 39.8 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER31833.1 - 0.0023 17.4 0.8 0.017 14.5 0.8 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER31833.1 - 0.018 14.7 1.8 0.12 11.9 1.7 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Phage_holin_5_2 PF16079.5 KER31833.1 - 0.037 14.3 0.2 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V 7tm_3 PF00003.22 KER31833.1 - 0.25 11.0 6.1 2.7 7.6 0.6 2.1 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR LIM PF00412.22 KER31834.1 - 4e-11 43.0 4.2 9.8e-11 41.7 4.2 1.7 1 0 0 1 1 1 1 LIM domain c-SKI_SMAD_bind PF08782.10 KER31834.1 - 9.7 6.5 9.4 2.9 8.2 0.7 2.6 2 1 0 2 2 2 0 c-SKI Smad4 binding domain Hus1 PF04005.12 KER31835.1 - 3.3e-50 170.8 0.0 1.2e-49 169.0 0.0 2.0 1 1 0 1 1 1 1 Hus1-like protein BRCT PF00533.26 KER31835.1 - 4.8e-12 46.1 0.0 6e-05 23.4 0.0 3.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KER31835.1 - 2.6e-09 36.9 0.7 2.7e-07 30.4 0.0 3.7 3 1 0 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 KER31835.1 - 1.9e-06 28.2 0.0 0.00021 21.6 0.0 3.2 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KER31835.1 - 1.1e-05 25.7 0.1 0.016 15.5 0.0 3.3 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain DUF3408 PF11888.8 KER31835.1 - 0.2 11.8 3.8 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) NitrOD5 PF11537.8 KER31838.1 - 0.057 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 ASH PF15780.5 KER31839.1 - 1.5e-22 79.6 17.4 0.025 14.8 0.0 12.9 12 2 1 13 13 13 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 KER31839.1 - 3.9e-06 26.7 1.5 12 5.8 0.0 7.1 7 0 0 7 7 7 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KER31839.1 - 1.7e-05 25.0 5.1 0.74 10.1 0.1 6.6 6 0 0 6 6 6 2 Transmembrane protein 131-like DUF1573 PF07610.11 KER31839.1 - 0.0023 17.9 0.0 9.4 6.3 0.0 6.3 7 1 1 8 8 8 1 Protein of unknown function (DUF1573) BEN PF10523.9 KER31839.1 - 0.0039 17.4 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 2 BEN domain Aldo_ket_red PF00248.21 KER31840.1 - 5.2e-92 308.2 0.0 1.8e-47 162.0 0.0 3.2 2 2 0 2 2 2 2 Aldo/keto reductase family zf-C5HC2 PF02928.16 KER31841.1 - 0.83 10.1 6.9 1.4 9.3 0.1 3.1 3 0 0 3 3 3 0 C5HC2 zinc finger MMS1_N PF10433.9 KER31842.1 - 5.8e-81 272.6 0.0 1.4e-80 271.3 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KER31842.1 - 1.3e-60 205.4 0.0 7e-60 203.0 0.0 2.3 2 1 0 2 2 2 1 CPSF A subunit region IP_trans PF02121.18 KER31844.1 - 8.8e-108 359.5 0.6 1e-107 359.3 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Pkinase PF00069.25 KER31845.1 - 6.9e-17 61.7 0.0 9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KER31845.1 - 2.7e-09 36.3 0.2 2.7e-09 36.3 0.2 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KER31845.1 - 5.4e-08 32.4 0.0 6.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER31845.1 - 0.00019 21.5 0.5 0.0047 16.9 0.2 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KER31845.1 - 0.033 13.6 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nup54 PF13874.6 KER31851.1 - 8.4e-33 113.4 0.0 8.4e-33 113.4 0.0 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 LIM PF00412.22 KER31853.1 - 3.2e-23 81.7 27.0 4.2e-12 46.1 7.5 2.1 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 KER31853.1 - 0.0006 19.4 19.2 0.8 9.3 0.1 5.2 5 0 0 5 5 5 4 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KER31853.1 - 0.2 11.7 28.8 39 4.4 8.7 4.5 2 2 0 2 2 2 0 Double zinc ribbon SelR PF01641.18 KER31853.1 - 1.2 9.2 12.9 1.2 9.2 2.1 2.8 3 0 0 3 3 3 0 SelR domain zinc-ribbons_6 PF07191.12 KER31853.1 - 1.5 8.8 27.2 4.7 7.3 11.3 3.3 2 2 1 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KER31853.1 - 9.7 6.4 32.4 7.7 6.7 7.5 4.5 4 1 0 4 4 4 0 Zinc ribbon domain FYDLN_acid PF09538.10 KER31853.1 - 9.9 6.9 7.0 21 5.9 2.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Glyoxalase PF00903.25 KER31854.1 - 2.1e-09 37.7 0.0 8e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KER31854.1 - 6.8e-09 36.0 0.0 2.7e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KER31854.1 - 0.17 12.7 0.0 0.62 10.9 0.0 1.9 2 1 0 2 2 2 0 Glyoxalase-like domain DEAD PF00270.29 KER31856.1 - 1.5e-25 89.9 0.0 2.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER31856.1 - 3.4e-23 82.1 0.0 6.9e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER31856.1 - 1.4e-05 25.2 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KER31856.1 - 0.0049 16.6 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 KER31856.1 - 0.048 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KER31856.1 - 0.068 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flp_C PF05202.12 KER31856.1 - 0.089 12.3 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 Recombinase Flp protein Peptidase_C2 PF00648.21 KER31857.1 - 4.5e-75 252.4 0.1 1.1e-68 231.5 0.0 3.2 1 1 1 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 KER31857.1 - 6.3e-23 81.6 0.0 1.6e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III MMS19_N PF14500.6 KER31858.1 - 7.1e-54 183.1 0.5 9.8e-52 176.1 0.0 2.3 1 1 1 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KER31860.1 - 1.5e-08 34.2 0.8 3.6e-08 33.0 0.1 1.9 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KER31860.1 - 0.082 13.3 0.1 0.76 10.2 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats EF-hand_13 PF17958.1 KER31861.1 - 7.4e-33 112.2 0.0 2e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KER31861.1 - 1.1e-18 67.4 0.2 3.1e-17 62.8 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KER31861.1 - 2.4e-05 23.6 0.0 0.002 17.6 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER31861.1 - 0.0047 16.8 0.2 0.035 14.0 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KER31861.1 - 0.011 15.2 0.2 0.083 12.5 0.0 2.5 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 KER31861.1 - 0.086 13.2 0.3 21 5.5 0.1 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.6 KER31861.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Myb_DNA-bind_6 PF13921.6 KER31863.1 - 1e-05 25.6 0.1 3.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KER31863.1 - 7.9e-05 22.8 0.1 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KER31863.1 - 0.14 12.2 1.1 0.46 10.6 0.0 2.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ribosomal_S19 PF00203.21 KER31865.1 - 2.6e-33 113.7 1.5 3.5e-33 113.3 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S19 TPR_8 PF13181.6 KER31866.1 - 0.0061 16.7 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KER31866.1 - 0.0087 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER31866.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KER31866.1 - 0.055 13.3 0.3 0.1 12.5 0.1 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31866.1 - 0.067 13.9 0.2 0.14 12.9 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KER31867.1 - 0.0059 16.6 3.1 1.2 9.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31867.1 - 0.048 13.9 0.1 1.2 9.4 0.0 2.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KER31867.1 - 0.064 13.3 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 KER31867.1 - 0.14 12.1 4.5 1.7 8.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Dus PF01207.17 KER31868.1 - 1.1e-58 198.8 0.0 1.5e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_2 PF07719.17 KER31871.1 - 0.00014 21.7 9.5 0.091 12.9 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER31871.1 - 0.0051 16.9 8.7 0.0096 16.1 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER31871.1 - 0.017 15.0 12.7 0.15 11.9 1.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KER31871.1 - 0.055 14.0 4.7 0.085 13.4 0.3 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31871.1 - 0.17 12.6 0.3 0.17 12.6 0.3 3.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 KER31872.1 - 4.4e-66 223.1 0.0 6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER31872.1 - 2.4e-08 34.3 4.0 4.2e-08 33.5 4.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Retrotrans_gag PF03732.17 KER31872.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Peptidase_C1_2 PF03051.15 KER31872.1 - 0.043 12.6 0.3 0.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family CCDC66 PF15236.6 KER31873.1 - 8.5e-38 129.6 14.6 8.5e-38 129.6 14.6 2.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 zinc_ribbon_4 PF13717.6 KER31875.1 - 0.068 13.1 0.4 0.14 12.1 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S16 PF00886.19 KER31876.1 - 6.9e-16 58.1 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 zf-CRD PF17979.1 KER31877.1 - 8e-26 91.0 9.2 8e-26 91.0 9.2 2.9 2 1 1 3 3 3 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 KER31877.1 - 6.6e-11 42.4 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 KER31877.1 - 2.7e-05 24.1 5.6 6.2e-05 22.9 5.6 1.7 1 0 0 1 1 1 1 PBZ domain Yop-YscD_cpl PF16697.5 KER31877.1 - 0.035 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain AhpC-TSA PF00578.21 KER31879.1 - 2.9e-38 130.6 0.0 3.8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KER31879.1 - 5.1e-15 55.5 0.0 6.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KER31879.1 - 2.8e-10 39.9 0.1 5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin NICE-3 PF07406.11 KER31882.1 - 2.9e-17 63.2 0.5 2e-09 37.7 0.3 2.4 1 1 1 2 2 2 2 NICE-3 protein DUF4659 PF15558.6 KER31883.1 - 3.2e-06 26.3 40.4 3.2e-06 26.3 40.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4659) RVT_1 PF00078.27 KER31884.1 - 2.9e-08 33.5 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UcrQ PF02939.16 KER31885.1 - 6.9e-17 61.2 0.2 8.3e-17 60.9 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KER31885.1 - 0.00022 21.5 0.0 0.00026 21.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 HTH_6 PF01418.17 KER31887.1 - 0.031 14.2 0.2 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Spore_II_R PF09551.10 KER31887.1 - 0.33 11.4 2.7 0.67 10.4 1.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) CAP PF00188.26 KER31888.1 - 1.3e-18 68.0 0.0 1.7e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med19 PF10278.9 KER31888.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Glyco_transf_7C PF02709.14 KER31890.1 - 4.3e-07 29.5 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 KER31890.1 - 8.9e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KER31890.1 - 0.0056 16.2 0.0 0.18 11.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CRAL_TRIO PF00650.20 KER31891.1 - 3.7e-27 95.0 0.0 4.7e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Ribosomal_S18 PF01084.20 KER31892.1 - 6.5e-19 67.9 0.1 1.7e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 WD40 PF00400.32 KER31893.1 - 5.1e-15 55.6 6.9 3.7e-05 24.4 0.4 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31893.1 - 1e-11 45.0 0.1 4.1e-05 23.8 0.0 5.1 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER31893.1 - 3.1e-05 24.0 0.0 0.2 11.5 0.1 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 KER31896.1 - 1.5e-25 90.1 0.0 1.8e-24 86.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER31896.1 - 2.8e-16 59.6 0.0 2.8e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER31896.1 - 5.8e-05 22.5 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER31896.1 - 0.0039 16.2 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER31896.1 - 0.0065 16.4 0.4 0.011 15.6 0.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER31896.1 - 0.046 13.1 0.2 0.094 12.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER31896.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ATG13 PF10033.9 KER31897.1 - 0.022 14.5 0.2 0.059 13.0 0.1 1.7 1 1 1 2 2 2 0 Autophagy-related protein 13 AAA PF00004.29 KER31898.1 - 1.1e-42 145.6 0.1 4.5e-42 143.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KER31898.1 - 2.2e-22 78.8 0.1 4.3e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KER31898.1 - 7.4e-11 41.7 0.4 1.9e-10 40.4 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KER31898.1 - 1.8e-06 28.5 0.9 0.00035 21.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KER31898.1 - 5.8e-06 26.3 0.2 4.2e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KER31898.1 - 1.2e-05 25.1 0.0 3.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KER31898.1 - 0.00016 21.9 0.6 0.022 15.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KER31898.1 - 0.0006 20.0 0.0 0.0033 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KER31898.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KER31898.1 - 0.0027 18.2 0.0 0.0061 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KER31898.1 - 0.004 16.6 0.1 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KER31898.1 - 0.0068 15.9 0.1 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KER31898.1 - 0.0094 16.1 0.3 0.038 14.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KER31898.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KER31898.1 - 0.014 15.2 0.2 0.068 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KER31898.1 - 0.033 13.5 0.1 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 KER31898.1 - 0.043 13.4 0.6 0.31 10.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KER31898.1 - 0.05 13.3 0.1 0.26 11.0 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KER31898.1 - 0.07 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KER31898.1 - 0.079 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KER31898.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KER31898.1 - 0.096 12.6 0.4 1.8 8.5 0.0 2.3 1 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KER31898.1 - 0.17 12.2 0.2 0.59 10.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 KER31899.1 - 4.2e-05 22.9 0.0 6.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KER31899.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold 7TM_GPCR_Srw PF10324.9 KER31901.1 - 7.4e-32 110.9 18.0 9.8e-31 107.2 18.0 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER31901.1 - 3.1e-08 33.3 16.4 2e-07 30.6 16.0 2.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CBP_BcsG PF11658.8 KER31901.1 - 0.00027 19.5 0.1 0.013 13.9 0.0 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsG 7TM_GPCR_Srx PF10328.9 KER31901.1 - 0.0085 15.7 12.3 0.0085 15.7 12.3 2.3 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Ntox3 PF15536.6 KER31902.1 - 0.0069 16.4 0.0 4.1 7.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial toxin 3 Tgi2PP PF18250.1 KER31902.1 - 0.11 12.8 0.0 27 5.1 0.0 2.5 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP TraB PF01963.17 KER31903.1 - 8.4e-25 88.2 0.3 3.3e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 TraB family LANC_like PF05147.13 KER31903.1 - 0.024 13.2 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PRRSV_Env PF02340.15 KER31905.1 - 0.019 14.4 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 PRRSV putative envelope protein Sterol_MT_C PF08498.10 KER31905.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal TIP49 PF06068.13 KER31906.1 - 6.9e-270 893.8 9.8 1.1e-110 370.1 0.4 3.1 1 1 2 3 3 3 3 TIP49 P-loop domain RuvB_N PF05496.12 KER31906.1 - 2.9e-20 72.6 0.8 5.3e-07 29.5 0.0 3.8 3 0 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KER31906.1 - 3.5e-20 72.8 1.0 3.6e-07 30.7 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) TIP49_C PF17856.1 KER31906.1 - 1.1e-18 67.1 0.0 3.4e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_5 PF07728.14 KER31906.1 - 9.4e-11 41.9 0.1 0.0051 16.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KER31906.1 - 1.3e-08 35.4 0.0 0.019 15.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KER31906.1 - 8.5e-08 32.1 0.3 0.35 10.6 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_25 PF13481.6 KER31906.1 - 9.6e-08 31.8 0.0 0.084 12.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 KER31906.1 - 1.1e-07 32.3 0.0 0.024 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KER31906.1 - 1.1e-07 31.3 1.1 0.011 14.9 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 KER31906.1 - 1.2e-07 31.4 2.0 0.042 13.2 0.1 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KER31906.1 - 3.7e-07 30.4 0.0 0.062 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KER31906.1 - 4.6e-07 29.7 0.4 0.042 13.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 KER31906.1 - 5.6e-07 29.9 0.2 0.17 12.2 0.0 4.2 4 1 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KER31906.1 - 9.9e-07 28.4 0.3 0.096 12.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region PhoH PF02562.16 KER31906.1 - 1.3e-06 28.0 1.9 0.039 13.4 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DnaB_C PF03796.15 KER31906.1 - 1.3e-06 28.0 0.1 0.058 12.7 0.0 2.4 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_19 PF13245.6 KER31906.1 - 2.3e-06 28.0 4.0 0.61 10.4 0.1 4.0 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.6 KER31906.1 - 3.3e-06 27.6 0.3 3 8.3 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KER31906.1 - 3.5e-06 27.6 0.1 0.21 12.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_11 PF13086.6 KER31906.1 - 3.9e-06 26.9 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KER31906.1 - 4.7e-06 27.0 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 KER31906.1 - 7.5e-06 25.4 3.3 0.078 12.3 0.1 3.2 3 0 0 3 3 2 2 Zeta toxin NACHT PF05729.12 KER31906.1 - 2.2e-05 24.4 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ResIII PF04851.15 KER31906.1 - 3.6e-05 23.8 0.1 2.1 8.3 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KER31906.1 - 7.2e-05 22.2 0.1 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KER31906.1 - 7.4e-05 22.8 0.0 0.65 10.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KER31906.1 - 0.0001 22.1 1.0 1.6 8.4 0.1 3.4 3 0 0 3 3 3 2 AAA domain ATPase PF06745.13 KER31906.1 - 0.00069 19.0 1.3 1.1 8.6 0.0 2.8 3 0 0 3 3 2 2 KaiC NTPase_1 PF03266.15 KER31906.1 - 0.0027 17.7 0.1 4.2 7.3 0.0 2.9 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 KER31906.1 - 0.0027 17.6 0.0 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_3 PF07726.11 KER31906.1 - 0.0037 17.1 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) mCpol PF18182.1 KER31906.1 - 0.0042 17.4 0.2 6.6 7.1 0.0 3.0 3 0 0 3 3 2 0 minimal CRISPR polymerase domain Sigma54_activ_2 PF14532.6 KER31906.1 - 0.0048 17.0 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 KER31906.1 - 0.005 17.4 0.0 7 7.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter DEAD PF00270.29 KER31906.1 - 0.0054 16.5 5.0 1.2 8.9 0.1 3.0 4 0 0 4 4 2 2 DEAD/DEAH box helicase AAA_23 PF13476.6 KER31906.1 - 0.0054 17.2 0.1 6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KER31906.1 - 0.0061 16.5 0.0 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain IPT PF01745.16 KER31906.1 - 0.0072 15.7 0.8 4.3 6.6 0.0 2.8 3 0 0 3 3 2 0 Isopentenyl transferase T2SSE PF00437.20 KER31906.1 - 0.0078 15.3 0.1 5.7 5.9 0.0 3.0 4 0 0 4 4 4 0 Type II/IV secretion system protein KTI12 PF08433.10 KER31906.1 - 0.0081 15.6 0.2 6.1 6.2 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 SRPRB PF09439.10 KER31906.1 - 0.022 14.2 0.0 13 5.2 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Cytidylate_kin PF02224.18 KER31906.1 - 0.026 14.3 0.2 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase GvpD PF07088.11 KER31906.1 - 0.027 13.1 0.7 14 4.2 0.0 3.4 4 0 0 4 4 4 0 GvpD gas vesicle protein DUF853 PF05872.12 KER31906.1 - 0.033 12.8 0.0 7.2 5.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.6 KER31906.1 - 0.033 13.9 0.6 16 5.3 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KER31906.1 - 0.036 13.2 0.1 9.5 5.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KER31906.1 - 0.037 13.7 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KER31906.1 - 0.041 13.7 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_32 PF13654.6 KER31906.1 - 0.09 11.5 0.0 12 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KER31906.1 - 0.098 12.9 2.9 10 6.4 0.2 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Tubulin PF00091.25 KER31906.1 - 0.14 12.3 0.3 24 5.0 0.1 2.5 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain DUF1827 PF08860.10 KER31906.1 - 0.19 12.0 4.7 12 6.2 0.2 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF1827) CbiA PF01656.23 KER31906.1 - 3.2 7.8 5.1 89 3.1 0.0 3.9 4 1 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ChaC PF04752.12 KER31907.1 - 1.1e-42 146.2 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein ChaC PF04752.12 KER31908.1 - 1e-17 64.7 1.1 1.6e-17 64.1 1.1 1.2 1 0 0 1 1 1 1 ChaC-like protein DUF4407 PF14362.6 KER31909.1 - 0.027 13.8 7.0 0.045 13.1 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 KER31909.1 - 0.031 14.7 3.5 0.031 14.7 3.5 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 RRF PF01765.19 KER31909.1 - 0.072 13.0 9.0 0.15 12.0 2.1 2.4 1 1 1 2 2 2 0 Ribosome recycling factor DUF16 PF01519.16 KER31909.1 - 0.14 12.7 12.1 0.27 11.7 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 KER31909.1 - 0.21 11.6 18.5 0.2 11.7 5.0 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 KER31909.1 - 0.38 10.5 3.8 0.17 11.6 0.2 2.2 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF948 PF06103.11 KER31909.1 - 0.42 10.9 3.6 5.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KER31909.1 - 0.54 10.3 20.5 2.3 8.3 6.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KER31909.1 - 0.67 10.5 4.3 1.6 9.3 1.1 2.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 KER31909.1 - 0.72 10.3 4.2 5 7.6 1.7 2.3 1 1 2 3 3 3 0 Type III cell invasion protein SipB DUF4085 PF13315.6 KER31909.1 - 0.89 9.1 5.9 0.27 10.8 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Mod_r PF07200.13 KER31909.1 - 1.3 9.2 19.7 2.2 8.4 8.9 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 KER31909.1 - 1.3 9.2 19.6 0.5 10.5 0.2 3.8 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 Tho2 PF11262.8 KER31909.1 - 2.6 7.2 14.0 0.8 8.9 5.0 2.2 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 KER31909.1 - 3.1 8.5 13.1 2.2 8.9 3.3 2.9 1 1 0 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 KER31909.1 - 3.5 5.5 8.4 0.15 10.0 1.1 1.9 1 1 1 2 2 2 0 Prominin LMBR1 PF04791.16 KER31909.1 - 6 5.7 6.7 6.3 5.6 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein JIP_LZII PF16471.5 KER31909.1 - 7.9 6.7 16.2 0.64 10.2 1.6 4.1 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II EF-hand_8 PF13833.6 KER31910.1 - 0.16 11.9 0.6 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Tropomyosin PF00261.20 KER31911.1 - 5.3e-07 29.2 31.9 3.7e-05 23.2 31.6 2.7 1 1 0 1 1 1 1 Tropomyosin ADIP PF11559.8 KER31911.1 - 0.0002 21.5 5.2 0.0002 21.5 5.2 3.5 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Filament PF00038.21 KER31911.1 - 0.00057 19.6 23.5 0.0014 18.3 23.5 1.5 1 1 0 1 1 1 1 Intermediate filament protein HrpB7 PF09486.10 KER31911.1 - 0.00098 19.5 1.8 0.00098 19.5 1.8 3.1 2 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 KER31911.1 - 0.0022 17.4 12.9 0.0049 16.3 9.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Fez1 PF06818.15 KER31911.1 - 0.0037 17.7 21.2 0.058 13.8 11.2 2.5 2 1 0 2 2 2 2 Fez1 FliJ PF02050.16 KER31911.1 - 0.0086 16.3 4.0 0.0086 16.3 4.0 3.5 2 1 1 3 3 3 1 Flagellar FliJ protein T7SS_ESX_EspC PF10824.8 KER31911.1 - 0.021 15.3 0.9 0.54 10.8 0.5 3.0 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm ATG16 PF08614.11 KER31911.1 - 0.024 14.8 4.8 0.024 14.8 4.8 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KER31911.1 - 0.036 14.2 20.4 0.079 13.1 0.9 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 KER31911.1 - 0.042 14.4 2.4 0.042 14.4 2.4 3.7 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 CC2-LZ PF16516.5 KER31911.1 - 0.044 14.2 2.0 0.044 14.2 2.0 3.7 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator NPV_P10 PF05531.12 KER31911.1 - 0.054 14.0 11.0 3.6 8.1 0.4 4.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.6 KER31911.1 - 0.1 12.2 19.3 0.21 11.2 4.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Streptin-Immun PF11083.8 KER31911.1 - 0.16 12.4 0.2 0.16 12.4 0.2 3.7 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein TSC22 PF01166.18 KER31911.1 - 0.18 12.1 0.5 0.18 12.1 0.5 3.6 3 1 1 4 4 3 0 TSC-22/dip/bun family Retrotrans_gag PF03732.17 KER31911.1 - 0.2 11.9 2.3 5.9 7.2 0.4 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein MAD PF05557.13 KER31911.1 - 0.22 9.9 28.3 0.27 9.6 14.2 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4446 PF14584.6 KER31911.1 - 0.32 11.0 0.1 0.32 11.0 0.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) WXG100 PF06013.12 KER31911.1 - 0.33 11.2 5.7 4.9 7.5 0.1 3.9 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Rho_Binding PF08912.11 KER31911.1 - 0.35 11.7 0.3 0.35 11.7 0.3 4.3 3 2 0 3 3 3 0 Rho Binding CENP-F_leu_zip PF10473.9 KER31911.1 - 0.55 10.3 34.8 0.82 9.7 2.1 3.8 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KER31911.1 - 0.82 10.1 20.8 1.3 9.5 0.1 4.8 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) YojJ PF10372.9 KER31911.1 - 1.2 9.3 6.2 4.3 7.5 0.0 3.9 4 1 1 5 5 4 0 Bacterial membrane-spanning protein N-terminus APG6_N PF17675.1 KER31911.1 - 1.3 9.6 36.7 0.13 12.8 8.9 3.3 1 1 1 2 2 1 0 Apg6 coiled-coil region DUF4988 PF16378.5 KER31911.1 - 2.1 8.0 9.1 0.2 11.3 0.3 2.6 3 0 0 3 3 2 0 Domain of unknown function DHR10 PF18595.1 KER31911.1 - 2.2 8.4 35.3 0.99 9.5 8.7 3.7 2 2 0 3 3 3 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 KER31911.1 - 2.6 8.1 17.0 0.4 10.7 1.8 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 KER31911.1 - 3.3 7.6 20.3 0.11 12.4 1.2 4.3 3 3 2 5 5 5 0 Prefoldin subunit Vac_Fusion PF02346.16 KER31911.1 - 4.1 7.1 8.8 0.62 9.7 0.3 3.2 4 0 0 4 4 3 0 Chordopoxvirus multifunctional envelope protein A27 Atg14 PF10186.9 KER31911.1 - 4.1 6.4 22.6 3.5 6.6 6.7 2.2 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 KER31911.1 - 4.5 6.9 17.6 0.65 9.6 3.4 3.3 3 0 0 3 3 3 0 GrpE Jnk-SapK_ap_N PF09744.9 KER31911.1 - 4.6 7.4 34.5 1.5 9.0 8.7 3.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 OmpH PF03938.14 KER31911.1 - 5.2 7.4 25.5 0.18 12.1 6.3 3.1 1 1 0 2 2 1 0 Outer membrane protein (OmpH-like) Nsp1_C PF05064.13 KER31911.1 - 6.4 6.6 15.8 1.3 8.9 0.2 4.0 3 2 1 4 4 4 0 Nsp1-like C-terminal region EMP24_GP25L PF01105.24 KER31911.1 - 6.7 6.6 17.6 2.3 8.2 1.8 3.4 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD CENP-H PF05837.12 KER31911.1 - 7.4 7.0 23.3 0.64 10.4 0.6 3.8 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 KER31911.1 - 8.4 6.6 20.4 1.1 9.4 0.3 4.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 API5 PF05918.11 KER31912.1 - 8.9e-102 341.5 0.0 1e-101 341.3 0.0 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 KER31912.1 - 0.0067 16.8 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats T6SS_VasJ PF16989.5 KER31912.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Nod1 PF17114.5 KER31912.1 - 0.097 12.8 1.5 0.21 11.7 0.4 2.1 1 1 1 2 2 2 0 Gef2-related medial cortical node protein Nod1 Focadhesin PF11229.8 KER31912.1 - 0.11 10.7 0.2 0.16 10.1 0.2 1.2 1 0 0 1 1 1 0 Focadhesin G10 PF01125.17 KER31913.1 - 4.4e-64 214.7 6.7 4.8e-64 214.5 6.7 1.0 1 0 0 1 1 1 1 G10 protein OrfB_IS605 PF01385.19 KER31913.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Probable transposase CD225 PF04505.12 KER31914.1 - 2.1e-06 27.8 3.6 2.1e-06 27.8 3.6 1.7 1 1 1 2 2 2 1 Interferon-induced transmembrane protein Sec7 PF01369.20 KER31915.1 - 2.6e-25 89.2 0.0 3.1e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain Integrin_alpha2 PF08441.12 KER31916.1 - 3.7e-22 78.8 0.0 6.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 KER31916.1 - 6.8e-12 45.3 14.4 1.7e-07 31.2 0.5 3.9 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 KER31916.1 - 2e-05 25.1 5.6 0.035 14.7 0.4 3.2 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ion_trans PF00520.31 KER31918.1 - 2.3e-26 92.5 16.2 1.2e-25 90.2 16.2 1.9 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER31918.1 - 9.9e-15 54.7 0.0 2.5e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ion_trans_2 PF07885.16 KER31918.1 - 1.2e-08 34.8 3.8 1.2e-08 34.8 3.8 1.9 2 0 0 2 2 2 1 Ion channel DUF4426 PF14467.6 KER31918.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) PKD_channel PF08016.12 KER31918.1 - 0.045 12.4 6.9 0.082 11.6 6.9 1.4 1 1 0 1 1 1 0 Polycystin cation channel Ets PF00178.22 KER31919.1 - 0.15 12.6 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 Ets-domain WD40 PF00400.32 KER31920.1 - 7.5e-10 39.2 15.2 0.019 15.8 0.0 6.0 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER31920.1 - 0.002 18.4 0.0 0.23 11.8 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CTP_transf_like PF01467.26 KER31922.1 - 7.2e-21 74.9 0.2 2.1e-10 40.9 0.0 3.8 4 0 0 4 4 4 3 Cytidylyltransferase-like fn3 PF00041.21 KER31924.1 - 0.017 15.5 0.2 0.13 12.6 0.0 2.2 2 1 0 2 2 2 0 Fibronectin type III domain DUF3504 PF12012.8 KER31925.1 - 5.3e-30 104.5 0.1 6.3e-22 78.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3504) Ras PF00071.22 KER31926.1 - 9.6e-47 158.6 0.1 1.3e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER31926.1 - 7.8e-30 103.6 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER31926.1 - 1.1e-10 41.2 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KER31926.1 - 2.6e-06 27.5 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KER31926.1 - 9.2e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KER31926.1 - 0.00012 22.1 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KER31926.1 - 0.00026 20.5 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KER31926.1 - 0.0019 18.7 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 KER31926.1 - 0.013 15.0 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 KER31926.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KER31926.1 - 0.017 15.5 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KER31926.1 - 0.025 15.0 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KER31926.1 - 0.047 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 KER31926.1 - 0.066 13.0 0.2 0.41 10.4 0.1 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KER31926.1 - 0.073 12.2 0.1 0.13 11.4 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 KER31926.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 KER31927.1 - 7.4e-95 317.1 0.0 3.8e-91 304.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER31927.1 - 1e-43 149.6 0.0 1.8e-42 145.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 KER31927.1 - 1.3e-29 102.1 0.4 1.1e-20 73.5 0.1 2.5 2 0 0 2 2 2 2 SH2 domain SH3_9 PF14604.6 KER31927.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KER31927.1 - 6e-08 32.2 0.1 1.6e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KER31927.1 - 9.4e-08 31.6 0.0 2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 KER31927.1 - 0.00044 20.3 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SH3_10 PF17902.1 KER31927.1 - 0.0024 17.9 0.0 0.01 15.8 0.0 2.3 1 1 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 KER31927.1 - 0.0034 16.4 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER31927.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KER31927.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MSP PF01716.18 KER31927.1 - 0.043 13.0 0.3 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide Kdo PF06293.14 KER31927.1 - 0.067 12.5 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3822 PF12864.7 KER31927.1 - 0.16 11.1 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3822) BIR PF00653.21 KER31928.1 - 1.6e-19 70.3 5.2 4.3e-19 68.9 5.2 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Tubulin PF00091.25 KER31934.1 - 8.5e-65 218.7 0.0 1.1e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER31934.1 - 3.1e-50 169.6 0.0 5.9e-50 168.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER31934.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Claudin_2 PF13903.6 KER31935.1 - 0.0005 19.9 16.0 0.0031 17.3 13.9 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Bac_export_2 PF01312.19 KER31935.1 - 0.1 11.8 3.8 0.14 11.3 3.8 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family zf-LITAF-like PF10601.9 KER31935.1 - 0.28 11.5 1.6 4.7 7.5 0.1 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF3742 PF12553.8 KER31935.1 - 0.95 9.6 0.0 0.95 9.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) DUF677 PF05055.12 KER31935.1 - 3.9 6.3 4.4 0.59 9.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Seryl_tRNA_N PF02403.22 KER31936.1 - 0.001 19.3 4.4 0.0031 17.7 2.0 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain She9_MDM33 PF05546.11 KER31936.1 - 0.0022 17.8 0.8 0.0022 17.8 0.8 1.7 2 0 0 2 2 2 1 She9 / Mdm33 family Golgin_A5 PF09787.9 KER31936.1 - 0.0076 15.8 4.7 0.54 9.7 0.0 2.4 2 1 0 2 2 2 2 Golgin subfamily A member 5 Mod_r PF07200.13 KER31936.1 - 0.045 13.9 3.5 0.076 13.1 1.1 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FTA4 PF13093.6 KER31936.1 - 0.065 13.1 1.0 0.12 12.2 1.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Carbpep_Y_N PF05388.11 KER31936.1 - 0.085 13.4 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide SLATT_1 PF18181.1 KER31936.1 - 0.41 10.6 4.3 0.54 10.2 1.2 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 SKA2 PF16740.5 KER31936.1 - 0.45 10.3 4.1 0.33 10.8 0.5 2.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 KER31936.1 - 0.52 10.4 8.5 1.1 9.3 5.8 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Adap_comp_sub PF00928.21 KER31937.1 - 5.6e-70 235.7 0.0 6.2e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ICL PF00463.21 KER31938.1 - 0.085 11.3 0.1 0.1 11.0 0.1 1.0 1 0 0 1 1 1 0 Isocitrate lyase family FliG_N PF14842.6 KER31941.1 - 5.5 7.6 9.4 27 5.4 0.1 4.3 2 1 2 4 4 4 0 FliG N-terminal domain FAM176 PF14851.6 KER31942.1 - 0.0057 16.3 0.6 0.0057 16.3 0.6 2.0 2 0 0 2 2 2 1 FAM176 family Clr2 PF10383.9 KER31947.1 - 0.13 13.1 0.3 0.35 11.6 0.3 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Profilin PF00235.19 KER31948.1 - 6.6e-06 26.4 0.0 0.00023 21.4 0.0 2.2 1 1 0 1 1 1 1 Profilin HEPN-like_int PF18867.1 KER31948.1 - 0.009 15.9 0.0 0.94 9.3 0.0 2.1 2 0 0 2 2 2 2 HEPN-like integron domain Guanylate_kin PF00625.21 KER31949.1 - 1.2e-41 142.4 0.0 2.8e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase PCI PF01399.27 KER31951.1 - 2.9e-24 85.6 1.5 2.9e-24 85.6 1.5 2.2 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KER31951.1 - 0.0024 17.8 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 KER31951.1 - 0.17 12.1 1.4 28 5.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ACDC PF14733.6 KER31951.1 - 0.65 10.3 6.2 15 6.0 0.5 3.7 3 1 1 4 4 4 0 AP2-coincident C-terminal FliS PF02561.14 KER31951.1 - 0.67 10.2 9.3 0.18 12.1 4.0 2.7 3 0 0 3 3 3 0 Flagellar protein FliS Ank_2 PF12796.7 KER31952.1 - 2.4e-19 69.7 1.3 1.3e-09 38.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER31952.1 - 2.4e-16 59.9 4.2 2.6e-06 27.8 0.7 3.7 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER31952.1 - 1.6e-14 52.5 1.9 0.0015 18.8 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KER31952.1 - 3.4e-14 52.7 5.6 3.5e-08 33.5 0.7 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KER31952.1 - 5.6e-14 51.9 2.3 0.00011 22.5 0.3 4.5 4 0 0 4 4 4 2 Ankyrin repeat DnaJ PF00226.31 KER31953.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain RhoGEF PF00621.20 KER31954.1 - 5.8e-10 39.7 4.7 5.8e-10 39.7 4.7 2.5 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 KER31954.1 - 7.2e-08 31.9 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER31954.1 - 3.2e-07 30.1 0.0 6.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER31954.1 - 2.1e-05 24.1 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KER31954.1 - 0.0072 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain ECH_2 PF16113.5 KER31954.1 - 0.96 8.9 4.0 0.2 11.1 0.4 1.6 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase TPR_2 PF07719.17 KER31955.1 - 5.4e-12 44.9 2.0 0.0023 17.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER31955.1 - 6.1e-09 35.3 1.5 6.8e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER31955.1 - 3.1e-06 26.8 5.5 0.0066 16.1 1.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KER31955.1 - 5e-06 26.3 1.1 0.0086 16.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KER31955.1 - 3e-05 24.4 3.1 5.9e-05 23.5 0.5 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 KER31955.1 - 0.00038 20.7 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.6 KER31955.1 - 0.0023 18.6 8.4 0.2 12.3 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KER31955.1 - 0.0033 17.9 1.3 0.0079 16.6 0.2 2.1 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KER31955.1 - 0.0045 17.2 2.2 0.069 13.4 1.7 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER31955.1 - 0.0056 17.4 4.1 0.55 11.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KER31955.1 - 0.021 15.2 1.2 0.96 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KER31955.1 - 0.032 14.3 3.0 0.12 12.5 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 KER31955.1 - 0.032 14.5 3.7 2 8.8 0.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER31955.1 - 0.048 13.7 0.2 1.3 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31955.1 - 2 9.2 7.7 4.8 8.0 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Sema PF01403.19 KER31958.1 - 5e-23 81.6 0.0 9.4e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Sema domain PSI PF01437.25 KER31958.1 - 0.00039 20.9 5.6 0.00039 20.9 5.6 4.8 5 0 0 5 5 5 1 Plexin repeat HEAT PF02985.22 KER31959.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.8 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 KER31959.1 - 0.0037 17.3 3.3 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KER31959.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Lysyl_oxidase PF01186.17 KER31960.1 - 6.5e-80 267.6 0.2 1e-79 267.0 0.2 1.3 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.18 KER31960.1 - 1.5e-34 118.5 6.2 2.3e-27 95.4 1.3 3.2 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 KER31960.1 - 4.4e-07 30.4 5.6 8e-06 26.3 0.7 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 KER31960.1 - 0.076 13.5 0.2 0.63 10.6 0.1 2.4 2 0 0 2 2 2 0 Hepsin, SRCR domain Lactamase_B_2 PF12706.7 KER31961.1 - 2e-10 40.5 0.0 0.00051 19.6 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KER31961.1 - 8.2e-06 26.0 0.0 2.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KER31961.1 - 0.00011 21.9 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease MFAP1 PF06991.11 KER31963.1 - 4e-69 232.8 22.8 4e-69 232.8 22.8 2.7 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing 6PF2K PF01591.18 KER31964.1 - 0.055 12.8 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase zf-ISL3 PF14690.6 KER31965.1 - 0.093 13.4 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Glyco_hydro_15 PF00723.21 KER31967.1 - 2.6e-80 270.4 0.0 3.9e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 tRNA-synt_2e PF02091.15 KER31967.1 - 0.044 13.0 0.0 6.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Glycyl-tRNA synthetase alpha subunit DUF3450 PF11932.8 KER31967.1 - 0.16 11.2 0.5 0.33 10.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KH_8 PF17903.1 KER31969.1 - 1.2e-31 108.6 0.1 2.5e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KER31969.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KER31969.1 - 0.036 13.9 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF866 PF05907.13 KER31970.1 - 3.2e-27 95.3 0.0 2.4e-23 82.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Hid1 PF12722.7 KER31972.1 - 7.9e-250 831.4 0.0 1.4e-247 823.9 0.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KER31972.1 - 1.1e-244 813.6 0.3 1.5e-244 813.1 0.3 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein HMG14_17 PF01101.18 KER31972.1 - 0.56 11.2 1.9 6.4 7.8 0.7 2.3 2 0 0 2 2 2 0 HMG14 and HMG17 MIG-14_Wnt-bd PF06664.12 KER31973.1 - 1.4e-75 254.3 32.3 1.4e-75 254.3 32.3 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion RhodobacterPufX PF11511.8 KER31973.1 - 0.082 12.5 0.3 0.082 12.5 0.3 3.3 4 0 0 4 4 4 0 Intrinsic membrane protein PufX fn2 PF00040.19 KER31975.1 - 6.5e-17 61.5 32.4 0.00016 21.9 0.2 6.3 5 1 0 5 5 5 4 Fibronectin type II domain GIY-YIG PF01541.24 KER31976.1 - 2.7e-06 27.6 1.1 5.8e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain 7tm_1 PF00001.21 KER31977.1 - 1.1e-10 41.4 0.2 1.8e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ANAPC4_WD40 PF12894.7 KER31978.1 - 0.011 16.0 0.0 0.11 12.9 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-met PF12874.7 KER31978.1 - 0.019 15.4 0.1 0.21 12.1 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PQQ_2 PF13360.6 KER31978.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain DivIC PF04977.15 KER31978.1 - 0.11 12.3 3.4 0.25 11.2 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KER31978.1 - 0.12 12.8 2.7 0.27 11.8 2.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2730 PF10805.8 KER31978.1 - 0.2 11.7 1.2 0.49 10.5 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Spc24 PF08286.11 KER31978.1 - 0.88 9.8 3.5 2.6 8.3 3.5 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 KER31978.1 - 0.91 10.2 4.4 2.4 8.8 4.4 1.7 1 0 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 KER31978.1 - 1.4 9.3 12.1 0.023 15.1 2.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) RRM_1 PF00076.22 KER31980.1 - 0.00036 20.3 0.6 0.0023 17.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KER31980.1 - 0.071 12.9 3.9 0.46 10.3 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) RPS31 PF17067.5 KER31980.1 - 0.16 12.2 0.1 31 4.8 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S31e SLC12 PF03522.15 KER31980.1 - 0.31 10.0 7.0 0.5 9.3 7.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AAA_23 PF13476.6 KER31980.1 - 0.34 11.4 6.0 0.67 10.4 6.0 1.6 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 KER31980.1 - 0.42 9.2 3.5 0.56 8.8 3.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KER31980.1 - 0.54 9.8 8.5 0.18 11.4 5.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 KER31980.1 - 1.5 7.2 15.6 2 6.8 15.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4192 PF13830.6 KER31980.1 - 1.5 8.8 9.6 2.6 8.0 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Tho2 PF11262.8 KER31980.1 - 1.8 7.7 8.2 2.9 7.0 8.2 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Rtf2 PF04641.12 KER31980.1 - 3.6 6.9 13.3 6.2 6.1 13.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 KER31980.1 - 5 5.8 7.5 7.5 5.2 7.5 1.3 1 0 0 1 1 1 0 Presenilin Atg14 PF10186.9 KER31980.1 - 6.9 5.7 12.7 10 5.1 12.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fis1_TPR_C PF14853.6 KER31981.1 - 1.4e-20 73.0 0.1 2.5e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KER31981.1 - 4.8e-08 32.5 0.0 9.3e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_1 PF00515.28 KER31981.1 - 0.00011 21.8 0.2 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER31981.1 - 0.00012 22.2 0.3 0.00063 19.9 0.1 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KER31981.1 - 0.0015 18.5 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1672 PF07901.11 KER31981.1 - 0.0065 15.8 0.1 0.0075 15.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1672) TPR_7 PF13176.6 KER31981.1 - 0.0099 15.9 0.0 0.031 14.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KER31981.1 - 0.012 16.2 0.0 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KER31981.1 - 0.027 15.3 0.0 0.13 13.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER31981.1 - 0.036 14.7 0.0 0.1 13.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KER31981.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Plasmid_parti PF01672.16 KER31981.1 - 0.15 12.8 0.3 0.33 11.6 0.1 1.7 2 0 0 2 2 2 0 Putative plasmid partition protein Kunitz_BPTI PF00014.23 KER31982.1 - 8.4e-122 397.4 140.2 4.9e-19 68.3 5.0 14.7 14 0 0 14 14 14 13 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 KER31983.1 - 9.3e-63 208.3 0.0 1.9e-12 47.1 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 KER31983.1 - 2e-42 143.6 0.1 2.4e-07 31.3 0.0 6.4 5 1 1 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 KER31983.1 - 1.1e-29 102.5 0.0 8.5e-06 26.0 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KER31983.1 - 2.5e-22 78.8 0.6 6.7e-06 26.2 0.0 6.1 5 2 1 6 6 6 4 Immunoglobulin domain V-set PF07686.17 KER31983.1 - 2e-19 69.8 0.1 0.00033 20.8 0.0 7.2 5 3 0 5 5 5 3 Immunoglobulin V-set domain BiPBP_C PF06832.12 KER31983.1 - 3.6e-08 33.3 0.0 0.77 9.8 0.0 5.2 5 0 0 5 5 5 3 Penicillin-Binding Protein C-terminus Family C1-set PF07654.15 KER31983.1 - 1.8e-06 28.2 0.0 3.6 8.0 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KER31983.1 - 1e-05 25.0 0.3 6.3 6.5 0.0 4.4 4 0 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 KER31983.1 - 3e-05 24.0 0.0 0.53 10.4 0.0 4.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KER31983.1 - 7.3e-05 22.9 0.0 5.3 7.4 0.0 4.6 4 1 0 4 4 4 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 KER31983.1 - 0.0019 18.4 0.0 21 5.4 0.0 3.9 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 HMG_box PF00505.19 KER31984.1 - 9.7e-26 90.0 0.9 1.8e-25 89.1 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER31984.1 - 1.2e-08 35.4 0.7 2.4e-08 34.5 0.7 1.5 1 0 0 1 1 1 1 HMG-box domain zf-C2H2 PF00096.26 KER31985.1 - 0.001 19.4 2.7 0.001 19.4 2.7 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER31985.1 - 0.081 13.8 7.1 0.09 13.7 2.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-B_box PF00643.24 KER31985.1 - 4.3 7.6 11.0 6.4 7.0 0.1 2.6 2 1 0 2 2 2 0 B-box zinc finger Lig_chan PF00060.26 KER31986.1 - 8.3e-19 67.9 2.5 1e-18 67.6 2.5 1.1 1 0 0 1 1 1 1 Ligand-gated ion channel Peptidase_U4 PF03419.13 KER31986.1 - 0.024 13.9 0.6 0.03 13.6 0.6 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA WD40 PF00400.32 KER31987.1 - 3.6e-08 33.9 0.2 0.84 10.6 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Alpha-amylase_C PF02806.18 KER31988.1 - 1.3e-26 92.8 0.0 7.2e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KER31988.1 - 5.4e-13 49.1 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KER31988.1 - 8e-13 48.7 0.0 3.5e-10 40.0 0.0 2.2 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Memo PF01875.17 KER31990.1 - 1.2e-15 57.4 0.0 1.9e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Memo-like protein Exo_endo_phos_2 PF14529.6 KER31990.1 - 0.18 11.6 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase HA2 PF04408.23 KER31992.1 - 1.4e-14 54.2 0.0 4.1e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KER31992.1 - 2.9e-13 50.1 0.3 1e-12 48.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER31992.1 - 2.3e-10 40.5 0.0 4.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KER31992.1 - 1.4e-05 25.4 0.0 5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KER31992.1 - 0.00014 22.2 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KER31992.1 - 0.002 18.5 0.0 0.006 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KER31992.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KER31992.1 - 0.018 14.3 0.0 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KER31992.1 - 0.018 15.5 0.0 0.065 13.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KER31992.1 - 0.023 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KER31992.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ALF PF03752.13 KER31992.1 - 0.071 13.1 0.0 0.071 13.1 0.0 2.1 2 0 0 2 2 2 0 Short repeats of unknown function AAA_16 PF13191.6 KER31992.1 - 0.1 13.0 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KER31992.1 - 0.15 12.1 0.1 2 8.5 0.1 2.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KER31992.1 - 0.18 11.8 0.0 14 5.6 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Apolipoprotein PF01442.18 KER31995.1 - 0.00069 19.5 0.2 0.0012 18.7 0.2 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4134 PF13572.6 KER31995.1 - 0.26 11.6 0.9 0.47 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) S4 PF01479.25 KER31997.1 - 4.4e-10 39.1 0.1 4.9e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KER31997.1 - 3.4e-08 34.3 0.5 4.9e-08 33.8 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SNF PF00209.18 KER31998.1 - 2.5e-35 122.2 30.5 8.6e-19 67.6 12.1 2.2 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family OFeT_1 PF16955.5 KER31998.1 - 0.0065 16.2 0.4 0.016 14.9 0.4 1.7 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter LEAP-2 PF07359.11 KER31998.1 - 0.085 12.7 0.2 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) RRM_1 PF00076.22 KER32001.1 - 3e-32 110.2 0.0 8.7e-18 63.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER32001.1 - 7e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KER32001.1 - 0.00034 20.6 0.0 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KER32001.1 - 0.00095 19.2 0.0 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KER32001.1 - 0.0069 16.4 0.0 0.06 13.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1241 PF06840.11 KER32003.1 - 1.1e-45 154.9 0.2 1.4e-45 154.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF3038 PF11237.8 KER32003.1 - 0.0098 16.0 3.8 0.014 15.5 3.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3038) Spore_III_AB PF09548.10 KER32003.1 - 0.016 15.3 0.6 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Focal_AT PF03623.13 KER32003.1 - 0.017 15.1 0.5 0.046 13.7 0.5 1.9 1 1 1 2 2 2 0 Focal adhesion targeting region Med11 PF10280.9 KER32003.1 - 0.044 14.2 0.8 0.087 13.3 0.8 1.5 1 0 0 1 1 1 0 Mediator complex protein Talin_middle PF09141.10 KER32003.1 - 0.061 13.4 1.0 0.23 11.5 1.1 1.9 2 0 0 2 2 2 0 Talin, middle domain Rogdi_lz PF10259.9 KER32003.1 - 0.081 12.4 0.6 0.098 12.1 0.6 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein PHD PF00628.29 KER32005.1 - 0.00019 21.3 2.5 0.00027 20.8 2.5 1.3 1 0 0 1 1 1 1 PHD-finger Thymosin PF01290.20 KER32006.1 - 4.7e-20 71.0 2.7 7.8e-12 44.7 0.1 2.1 1 1 1 2 2 2 2 Thymosin beta-4 family DUF4939 PF16297.5 KER32006.1 - 0.15 11.9 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) TTL PF03133.15 KER32007.1 - 6.2e-56 189.7 0.2 5.5e-38 130.8 0.1 2.7 2 1 1 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER32007.1 - 4.3e-07 29.5 0.0 1.2e-05 24.7 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER32007.1 - 0.00012 21.4 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp CNOT1_HEAT_N PF16419.5 KER32008.1 - 0.0016 18.2 0.5 0.24 11.0 0.1 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2280 PF10045.9 KER32008.1 - 0.002 18.4 6.0 0.37 11.1 1.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2280) ZnuA PF01297.17 KER32008.1 - 0.17 11.2 2.5 10 5.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic DUF5064 PF16703.5 KER32008.1 - 0.19 12.2 2.6 0.98 9.9 0.6 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5064) SLATT_6 PF18169.1 KER32008.1 - 0.36 10.4 7.6 0.82 9.2 0.4 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 T3SSipB PF16535.5 KER32008.1 - 0.52 10.8 10.1 0.15 12.5 5.3 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB CutA1 PF03091.15 KER32008.1 - 0.85 9.5 3.4 26 4.8 0.2 2.6 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Peptidase_M29 PF02073.15 KER32008.1 - 1.2 7.8 8.5 0.89 8.3 2.1 2.2 2 0 0 2 2 2 0 Thermophilic metalloprotease (M29) NRBF2 PF08961.10 KER32008.1 - 1.7 8.2 17.4 1 8.9 1.7 3.1 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator ArsC PF03960.15 KER32008.1 - 1.9 8.5 5.2 27 4.8 0.4 3.0 3 0 0 3 3 3 0 ArsC family DUF4241 PF14025.6 KER32008.1 - 2.1 8.6 3.7 7.1 6.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) Baculo_PEP_C PF04513.12 KER32008.1 - 2.4 8.2 5.1 5.4 7.1 0.6 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cas_Cmr5 PF09701.10 KER32008.1 - 2.4 8.5 13.4 2.5 8.4 1.4 2.6 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) T3SS_basalb_I PF17001.5 KER32008.1 - 2.6 8.7 6.4 32 5.2 2.0 3.1 2 1 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI ATP-grasp_4 PF13535.6 KER32008.1 - 3.4 7.2 5.2 23 4.5 0.2 2.8 2 1 1 3 3 3 0 ATP-grasp domain Cytochrom_B562 PF07361.11 KER32008.1 - 6.1 7.6 11.8 14 6.4 0.7 2.7 2 0 0 2 2 2 0 Cytochrome b562 HR1 PF02185.16 KER32008.1 - 7.1 6.8 26.6 0.75 9.9 10.1 3.4 3 1 0 3 3 2 0 Hr1 repeat Helicase_C_2 PF13307.6 KER32008.1 - 7.2 6.8 8.0 33 4.6 0.1 3.4 1 1 1 3 3 3 0 Helicase C-terminal domain TPR_MLP1_2 PF07926.12 KER32008.1 - 8.8 6.4 33.9 0.81 9.7 1.1 3.8 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Elong_Iki1 PF10483.9 KER32009.1 - 1.2e-06 28.3 0.6 4.7e-06 26.3 0.2 1.9 1 1 1 2 2 2 1 Elongator subunit Iki1 Lebercilin PF15619.6 KER32011.1 - 3.9e-46 157.2 36.7 3.9e-46 157.2 36.7 2.9 3 0 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease zf-AD PF07776.15 KER32011.1 - 0.12 12.6 1.6 1.7 9.0 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) YcaO PF02624.16 KER32011.1 - 1.1 8.5 3.3 2.3 7.4 3.3 1.5 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Pkinase_Tyr PF07714.17 KER32012.1 - 5.3e-54 183.2 0.0 6.5e-52 176.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.24 KER32012.1 - 6.5e-36 122.9 0.6 9.5e-20 70.8 0.0 2.6 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 KER32012.1 - 1.2e-24 87.1 0.0 1.6e-23 83.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Furin-like PF00757.20 KER32012.1 - 3.7e-20 72.3 114.1 1.5e-17 63.8 39.9 6.2 3 2 3 6 6 6 4 Furin-like cysteine rich region GF_recep_IV PF14843.6 KER32012.1 - 1.2e-16 60.7 104.8 9.4e-06 25.5 3.5 6.8 3 2 2 7 7 7 5 Growth factor receptor domain IV DUF429 PF04250.13 KER32012.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF429) KH_1 PF00013.29 KER32015.1 - 3.1e-61 203.1 17.4 5.8e-16 58.1 0.2 4.5 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.10 KER32015.1 - 2e-26 91.2 24.1 7.2e-15 54.2 5.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1897) rve PF00665.26 KER32015.1 - 7.1e-25 87.5 0.0 1.8e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain KH_2 PF07650.17 KER32015.1 - 7.9e-15 54.5 5.5 0.0046 16.8 0.0 4.7 4 0 0 4 4 4 4 KH domain Integrase_H2C2 PF17921.1 KER32015.1 - 8.5e-13 48.2 0.0 2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain KH_4 PF13083.6 KER32015.1 - 7.1e-08 32.2 8.3 0.0032 17.3 0.1 5.0 5 0 0 5 5 5 3 KH domain rve_3 PF13683.6 KER32015.1 - 0.0011 18.7 0.0 0.0044 16.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KER32015.1 - 0.045 14.0 0.4 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger KH_5 PF13184.6 KER32015.1 - 1.9 8.6 4.2 27 4.9 0.0 3.9 4 0 0 4 4 4 0 NusA-like KH domain GSH_synth_ATP PF03917.17 KER32016.1 - 3.5e-76 256.4 0.0 6.3e-76 255.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KER32016.1 - 8.3e-27 93.6 0.0 1.5e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EnY2 PF10163.9 KER32017.1 - 8.6e-32 109.4 1.1 1.8e-31 108.3 0.1 1.9 2 0 0 2 2 2 1 Transcription factor e(y)2 Sin3a_C PF16879.5 KER32017.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 C-terminal domain of Sin3a protein FliL PF03748.14 KER32017.1 - 0.1 13.2 0.3 1.4 9.5 0.1 2.2 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL VASP_tetra PF08776.11 KER32017.1 - 0.15 11.6 1.9 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain DUF2046 PF09755.9 KER32022.1 - 2.8e-107 358.5 51.9 3.4e-84 282.7 36.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) HALZ PF02183.18 KER32022.1 - 0.0076 16.5 0.5 0.0076 16.5 0.5 5.8 6 1 1 7 7 7 2 Homeobox associated leucine zipper ZapB PF06005.12 KER32022.1 - 0.012 16.0 8.1 0.012 16.0 8.1 5.5 4 2 1 5 5 5 0 Cell division protein ZapB DASH_Dad4 PF08650.10 KER32022.1 - 2.9 7.9 12.6 0.14 12.1 0.4 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 WD40 PF00400.32 KER32025.1 - 3.6e-36 122.5 38.6 2e-06 28.4 0.2 8.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER32025.1 - 8.4e-07 29.2 2.0 0.16 12.3 0.0 5.0 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER32025.1 - 4.3e-06 25.7 14.2 0.2 10.2 0.1 6.2 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.7 KER32025.1 - 0.0076 16.1 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER32025.1 - 0.18 11.8 1.4 0.35 10.8 0.2 2.2 2 0 0 2 2 2 0 F-box domain PTH2 PF01981.16 KER32026.1 - 1.7e-45 154.0 0.0 2.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ANAPC4_WD40 PF12894.7 KER32027.1 - 0.012 15.9 0.0 21 5.5 0.0 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SKA2 PF16740.5 KER32027.1 - 1.2 9.0 4.4 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 GIT_CC PF16559.5 KER32027.1 - 7.4 6.5 6.4 1.9 8.4 0.8 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nup84_Nup100 PF04121.13 KER32028.1 - 1.3e-115 387.2 2.0 3.6e-63 213.9 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 RMI1_N PF08585.12 KER32028.1 - 4.4e-16 59.3 0.1 3.2e-14 53.2 0.1 2.4 1 1 0 1 1 1 1 RecQ mediated genome instability protein Peptidase_S51 PF03575.17 KER32028.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 7tm_1 PF00001.21 KER32032.1 - 2.9e-31 108.8 0.0 4.4e-31 108.2 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NCD2 PF04905.13 KER32034.1 - 1.8e-20 73.2 0.7 2.2e-10 40.6 0.2 2.9 2 0 0 2 2 2 2 NAB conserved region 2 (NCD2) LRR_8 PF13855.6 KER32034.1 - 2.6e-06 27.1 0.5 6.6e-06 25.8 0.5 1.7 1 0 0 1 1 1 1 Leucine rich repeat WD40 PF00400.32 KER32034.1 - 1e-05 26.1 0.2 0.07 14.0 0.0 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat LRR_4 PF12799.7 KER32034.1 - 0.00016 22.0 7.1 0.0024 18.3 3.3 2.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KER32034.1 - 0.28 11.4 1.8 1e+02 3.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KER32034.1 - 0.38 11.5 7.1 3.4 8.6 0.8 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat GNAT_like PF18407.1 KER32038.1 - 8.6 6.8 7.7 0.47 10.8 2.1 1.9 2 1 0 2 2 2 0 GCN5-related N-acetyltransferase like domain Ion_trans PF00520.31 KER32039.1 - 9.3e-115 382.0 33.1 7.2e-61 205.5 3.5 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 KER32039.1 - 7.7e-07 28.1 43.3 9.1e-07 27.9 8.0 5.1 4 1 1 5 5 5 5 Polycystin cation channel DUF4834 PF16118.5 KER32039.1 - 0.0096 16.9 3.2 10 7.2 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4834) Ion_trans PF00520.31 KER32040.1 - 1e-14 54.4 5.4 4e-14 52.5 5.4 1.8 1 1 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 KER32041.1 - 2.2e-86 289.1 27.1 2.1e-54 184.4 11.5 3.2 3 0 0 3 3 3 3 Ion transport protein Ca_chan_IQ PF08763.11 KER32041.1 - 5.2e-30 103.5 0.0 1.1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 KER32041.1 - 8.1e-27 92.8 0.0 1.6e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 KER32041.1 - 0.022 13.4 25.3 0.42 9.2 0.2 4.2 3 1 1 4 4 4 0 Polycystin cation channel BTB PF00651.31 KER32042.1 - 7.5e-11 42.2 0.2 1.6e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Asp PF00026.23 KER32043.1 - 2e-115 385.6 0.9 2.4e-115 385.3 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER32043.1 - 3.5e-16 59.9 2.0 3.2e-14 53.5 2.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KER32043.1 - 3.3e-05 23.7 0.0 9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KER32043.1 - 0.00031 21.3 0.4 2.2 9.0 0.1 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KER32043.1 - 0.011 16.2 0.0 3.1 8.4 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sina PF03145.16 KER32044.1 - 5.3e-82 274.6 0.1 8.5e-82 273.9 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_4 PF15227.6 KER32044.1 - 0.015 15.5 7.2 0.055 13.6 7.2 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KER32044.1 - 0.057 13.3 10.5 1.3 8.9 11.3 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KER32044.1 - 0.14 12.0 13.4 0.096 12.5 10.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER32044.1 - 2 8.5 15.6 2.2 8.3 12.3 2.7 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_14 PF17978.1 KER32044.1 - 3.1 8.3 6.1 11 6.6 4.8 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain His_Phos_2 PF00328.22 KER32048.1 - 0.00027 20.4 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KER32049.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) UPRTase PF14681.6 KER32051.1 - 6.4e-47 159.7 0.0 1e-46 159.0 0.0 1.3 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KER32051.1 - 0.00014 21.4 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4218 PF13960.6 KER32054.1 - 0.033 13.8 0.5 0.062 12.9 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) PAP2 PF01569.21 KER32055.1 - 0.022 14.5 1.2 0.039 13.7 1.2 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF2062 PF09835.9 KER32055.1 - 0.068 13.0 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) SPRR2 PF14820.6 KER32055.1 - 0.073 13.2 3.3 1.1 9.4 0.2 2.2 2 0 0 2 2 2 0 Small proline-rich 2 CLN3 PF02487.17 KER32056.1 - 1.3e-12 47.5 1.7 1.9e-12 47.0 1.7 1.1 1 0 0 1 1 1 1 CLN3 protein DUF3325 PF11804.8 KER32056.1 - 0.11 12.7 2.3 0.31 11.2 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Tubulin PF00091.25 KER32059.1 - 9.9e-68 228.2 0.0 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER32059.1 - 1.6e-50 170.5 0.0 2.5e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KER32059.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain 5_nucleotid_C PF02872.18 KER32060.1 - 1.4e-36 126.1 0.0 2.6e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KER32060.1 - 2.8e-07 31.2 0.1 4.7e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RVT_1 PF00078.27 KER32061.1 - 0.0019 17.7 0.0 0.0019 17.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAP PF00188.26 KER32062.1 - 7.6e-23 81.7 0.7 9.1e-23 81.5 0.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GFO_IDH_MocA_C PF02894.17 KER32062.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PDEase_I PF00233.19 KER32063.1 - 2e-88 296.2 0.9 3.5e-88 295.3 0.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 KER32063.1 - 5.4e-30 104.5 2.6 5.4e-30 104.5 2.6 2.4 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DeoC PF01791.9 KER32064.1 - 5.3e-18 65.5 0.0 8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF4516 PF14990.6 KER32064.1 - 0.016 14.9 0.4 0.034 13.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) URO-D PF01208.17 KER32065.1 - 3.3e-126 421.1 0.0 3.7e-126 420.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) fn3 PF00041.21 KER32066.1 - 9.5e-08 32.3 13.3 0.002 18.5 0.7 5.0 5 1 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER32066.1 - 0.00014 22.3 5.4 0.29 11.7 0.5 4.5 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KER32067.1 - 0.0017 18.8 3.5 0.79 10.3 0.7 3.1 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KER32067.1 - 0.074 13.4 2.2 12 6.3 0.0 3.3 3 1 0 3 3 3 0 Fibronectin type III domain Git3 PF11710.8 KER32068.1 - 0.057 13.2 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 HMG_box PF00505.19 KER32069.1 - 2.4e-13 50.3 0.2 4.7e-12 46.2 0.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KER32069.1 - 0.13 11.6 0.1 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KER32069.1 - 0.17 12.5 0.3 2.9 8.6 0.0 2.4 2 0 0 2 2 2 0 HMG-box domain Histone PF00125.24 KER32070.1 - 1e-32 113.3 1.2 1.5e-32 112.7 0.7 1.5 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KER32070.1 - 0.044 14.0 0.2 0.085 13.0 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) fn3 PF00041.21 KER32071.1 - 3.2e-13 49.8 0.8 0.0086 16.4 0.0 5.1 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER32071.1 - 1.3e-08 35.3 0.4 0.039 14.5 0.0 5.2 5 0 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 KER32071.1 - 0.021 15.1 0.0 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Plk4_PB1 PF18190.1 KER32072.1 - 0.013 15.6 0.0 0.054 13.7 0.0 1.8 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 1 FERM_M PF00373.18 KER32073.1 - 1.2e-18 67.7 0.9 3.7e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 KER32073.1 - 1.3e-17 63.4 0.1 2.6e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 KER32073.1 - 4.2e-10 39.9 0.0 8.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Malt_amylase_C PF16657.5 KER32075.1 - 0.054 13.6 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Arm_3 PF16186.5 KER32076.1 - 0.051 13.1 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Atypical Arm repeat Ank_2 PF12796.7 KER32078.1 - 5.9e-141 459.4 30.6 4.5e-19 68.8 1.1 12.8 4 4 8 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 KER32078.1 - 3e-112 362.6 43.5 2.4e-06 27.7 0.0 25.2 25 0 0 25 25 25 21 Ankyrin repeat Ank_4 PF13637.6 KER32078.1 - 1.6e-105 344.2 17.7 9.1e-11 42.1 0.0 16.7 9 4 9 19 19 19 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32078.1 - 1.5e-104 329.1 28.7 0.00016 21.8 0.0 25.0 25 0 0 25 25 25 21 Ankyrin repeat Ank_5 PF13857.6 KER32078.1 - 8.2e-87 284.1 41.0 5.5e-07 29.7 0.3 21.5 5 5 19 24 24 24 23 Ankyrin repeats (many copies) KH_1 PF00013.29 KER32078.1 - 2.2e-08 33.8 0.3 5.3e-08 32.6 0.3 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KER32078.1 - 0.00041 20.2 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 KH domain Archaeal_AmoA PF12942.7 KER32078.1 - 0.18 11.5 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) Cnd1 PF12717.7 KER32080.1 - 0.053 13.6 2.4 1.5 8.9 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RVT_1 PF00078.27 KER32081.1 - 1.9e-28 99.5 0.0 3.7e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FERM_C PF09380.10 KER32081.1 - 4e-24 84.8 0.0 8.2e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain ERM PF00769.19 KER32081.1 - 4.7e-19 69.2 50.8 4.7e-19 69.2 50.8 2.7 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_N PF09379.10 KER32081.1 - 5.1e-14 52.0 0.0 3.4e-12 46.1 0.0 2.9 1 1 1 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 KER32081.1 - 3.9e-09 36.9 0.3 3.9e-09 36.9 0.3 2.5 2 1 0 2 2 2 1 FERM central domain Cauli_AT PF03233.13 KER32081.1 - 0.36 10.7 2.3 0.9 9.5 2.3 1.6 1 0 0 1 1 1 0 Aphid transmission protein Ank_2 PF12796.7 KER32082.1 - 3.5e-22 78.8 0.7 5.9e-10 39.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER32082.1 - 4.3e-17 62.2 0.2 2.2e-05 24.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER32082.1 - 1.5e-15 57.0 0.6 5e-06 26.7 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32082.1 - 1e-13 50.1 0.1 0.0018 18.6 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KER32082.1 - 4.2e-11 42.8 4.3 0.095 13.2 0.0 5.2 4 1 0 4 4 4 4 Ankyrin repeat TPR_1 PF00515.28 KER32083.1 - 1.8e-34 116.1 7.0 1e-11 44.1 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER32083.1 - 2.6e-27 92.7 5.3 1.6e-09 37.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER32083.1 - 1.9e-24 85.0 6.8 3.3e-11 42.7 0.0 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 KER32083.1 - 1.4e-22 77.9 6.4 3e-08 33.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KER32083.1 - 8e-19 66.2 1.1 3.5e-06 26.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER32083.1 - 1e-16 60.0 6.0 4.7e-05 23.5 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER32083.1 - 8.4e-15 54.2 1.3 6.4e-05 23.4 0.1 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER32083.1 - 2.3e-13 50.2 8.8 2.5e-08 34.1 0.5 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER32083.1 - 1.8e-10 41.2 2.8 5.4e-05 23.6 1.8 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER32083.1 - 1.5e-09 38.4 0.9 5.3e-05 23.8 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER32083.1 - 4.3e-09 36.4 2.1 2.6e-05 24.3 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KER32083.1 - 1.6e-07 31.5 2.0 0.07 13.8 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KER32083.1 - 1.5e-06 27.7 0.4 0.021 14.0 0.1 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER32083.1 - 5.5e-06 26.4 2.7 0.049 13.7 0.1 3.4 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KER32083.1 - 1.2e-05 25.0 6.2 0.021 14.7 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KER32083.1 - 0.00028 20.3 1.9 0.13 11.7 0.1 3.3 3 0 0 3 3 3 1 SHNi-TPR NARP1 PF12569.8 KER32083.1 - 0.00034 19.6 0.8 0.028 13.3 0.2 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 MIT PF04212.18 KER32083.1 - 0.0011 18.9 6.0 0.069 13.2 0.2 2.9 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KER32083.1 - 0.0011 19.4 2.0 0.066 13.7 2.0 2.7 1 1 0 1 1 1 1 Bacterial transcriptional activator domain NRBF2_MIT PF17169.4 KER32083.1 - 0.006 16.8 1.1 0.011 15.9 0.3 1.8 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 ANAPC3 PF12895.7 KER32083.1 - 0.032 14.4 4.2 2.2 8.5 1.1 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 KER32083.1 - 0.038 13.7 0.1 1.7 8.3 0.0 2.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Clathrin PF00637.20 KER32083.1 - 0.052 13.4 0.4 0.33 10.8 0.1 2.4 3 0 0 3 3 2 0 Region in Clathrin and VPS TPR_21 PF09976.9 KER32083.1 - 0.13 11.9 3.3 6.5 6.4 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 KER32083.1 - 0.15 12.1 0.9 13 5.8 0.9 2.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 KER32083.1 - 0.29 11.5 0.9 15 6.1 0.1 2.5 2 0 0 2 2 2 0 PPR repeat DUF5113 PF17140.4 KER32083.1 - 0.33 10.8 1.6 0.96 9.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) RPN7 PF10602.9 KER32083.1 - 0.41 10.3 5.0 3.2 7.4 0.2 2.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 F-box PF00646.33 KER32084.1 - 4.9e-08 32.7 0.8 1.1e-07 31.6 0.8 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KER32084.1 - 6.8e-06 26.7 8.6 0.052 14.4 1.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KER32084.1 - 0.00053 19.8 0.2 0.0013 18.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KER32084.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box PQQ_3 PF13570.6 KER32084.1 - 2.1 8.9 6.6 2.4 8.7 0.0 3.8 4 1 0 4 4 4 0 PQQ-like domain ADK PF00406.22 KER32085.1 - 5.1e-88 292.9 0.0 5.5e-17 62.3 0.0 6.2 6 0 0 6 6 6 5 Adenylate kinase AAA_17 PF13207.6 KER32085.1 - 3.2e-48 163.6 0.0 6.6e-10 39.5 0.0 6.6 7 0 0 7 7 6 5 AAA domain AAA_33 PF13671.6 KER32085.1 - 6e-29 101.0 0.0 0.0001 22.5 0.0 6.4 6 0 0 6 6 6 5 AAA domain AAA_18 PF13238.6 KER32085.1 - 5e-28 98.3 1.7 0.00071 20.1 0.0 7.3 7 0 0 7 7 6 5 AAA domain AAA PF00004.29 KER32085.1 - 1.7e-26 93.2 0.7 0.0054 17.1 0.0 6.5 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KER32085.1 - 2.6e-24 86.3 0.2 0.0021 18.3 0.0 6.6 6 0 0 6 6 6 5 AAA domain NACHT PF05729.12 KER32085.1 - 7e-18 65.1 4.1 0.033 14.1 0.0 6.5 6 0 0 6 6 6 5 NACHT domain AAA_24 PF13479.6 KER32085.1 - 3.7e-16 59.4 0.3 0.52 10.0 0.0 6.3 6 0 0 6 6 6 5 AAA domain KTI12 PF08433.10 KER32085.1 - 5.8e-15 55.5 0.4 0.63 9.4 0.0 6.3 6 0 0 6 6 6 4 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 KER32085.1 - 1.4e-13 51.6 0.1 1.2 9.4 0.0 8.7 9 0 0 9 9 9 2 Hydin Adenylate kinase-like domain MMR_HSR1 PF01926.23 KER32085.1 - 4.2e-13 49.4 0.0 0.71 10.0 0.0 6.5 6 0 0 6 6 6 3 50S ribosome-binding GTPase Roc PF08477.13 KER32085.1 - 2e-11 44.2 2.4 2.2 8.5 0.0 6.4 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 KER32085.1 - 5.7e-11 42.2 0.4 2 7.8 0.0 6.3 6 0 0 6 6 6 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KER32085.1 - 9.5e-11 42.4 0.0 5.1 7.4 0.0 6.4 6 0 0 6 6 6 0 AAA ATPase domain RNA_helicase PF00910.22 KER32085.1 - 1.8e-10 41.2 4.5 4.1 7.8 0.0 6.8 7 0 0 7 7 6 0 RNA helicase AAA_5 PF07728.14 KER32085.1 - 2e-10 40.8 1.3 5.3 7.1 0.0 6.8 6 0 0 6 6 6 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KER32085.1 - 9.5e-10 38.2 0.0 0.69 9.3 0.0 6.2 6 0 0 6 6 6 2 Bacterial TniB protein 6PF2K PF01591.18 KER32085.1 - 9.7e-10 38.1 0.2 0.098 11.9 0.0 5.9 6 0 0 6 6 6 2 6-phosphofructo-2-kinase AAA_22 PF13401.6 KER32085.1 - 2.2e-09 37.7 0.5 6.7 7.0 0.0 6.6 6 0 0 6 6 6 0 AAA domain RuvB_N PF05496.12 KER32085.1 - 2.4e-09 37.1 0.0 1.3 8.7 0.0 6.0 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 KER32085.1 - 2.7e-09 36.7 0.1 4.5 6.7 0.0 6.2 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit SKI PF01202.22 KER32085.1 - 3e-09 37.2 0.0 0.97 9.5 0.0 5.9 6 0 0 6 6 6 2 Shikimate kinase IstB_IS21 PF01695.17 KER32085.1 - 3.1e-09 36.8 0.0 1.3 8.7 0.0 6.1 6 0 0 6 6 6 1 IstB-like ATP binding protein PduV-EutP PF10662.9 KER32085.1 - 1.6e-08 34.4 2.1 1.3 8.7 0.0 6.0 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KER32085.1 - 2.7e-08 34.4 0.0 11 6.5 0.0 6.3 6 0 0 6 6 6 0 ABC transporter TsaE PF02367.17 KER32085.1 - 9.8e-08 32.0 0.0 15 5.6 0.0 6.4 6 0 0 6 6 6 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KER32085.1 - 1.1e-07 32.0 0.0 21 5.0 0.0 6.0 6 0 0 6 6 6 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 KER32085.1 - 5.2e-06 26.1 1.0 14 5.2 0.0 6.2 6 0 0 6 6 6 0 Ferrous iron transport protein B AAA_7 PF12775.7 KER32085.1 - 6.1e-06 25.9 0.0 34 3.9 0.0 6.1 6 0 0 6 6 6 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KER32085.1 - 1.1e-05 24.8 0.0 0.64 9.3 0.0 5.5 6 0 0 6 6 6 1 Zeta toxin Arf PF00025.21 KER32085.1 - 2.1e-05 24.0 0.0 24 4.3 0.0 6.0 6 0 0 6 6 6 0 ADP-ribosylation factor family AAA_30 PF13604.6 KER32085.1 - 2.2e-05 24.3 0.0 28 4.4 0.0 5.8 6 0 0 6 6 6 0 AAA domain AAA_25 PF13481.6 KER32085.1 - 0.00012 21.8 3.0 49 3.4 0.0 6.7 8 0 0 8 8 7 0 AAA domain NTPase_1 PF03266.15 KER32085.1 - 0.00012 22.0 4.6 25 4.7 0.0 6.2 6 0 0 6 6 6 0 NTPase dNK PF01712.19 KER32085.1 - 0.00067 19.6 1.6 17 5.2 0.0 5.6 6 0 0 6 6 5 0 Deoxynucleoside kinase AAA_14 PF13173.6 KER32085.1 - 0.00081 19.4 1.6 20 5.2 0.0 5.6 6 0 0 6 6 5 0 AAA domain Cytidylate_kin PF02224.18 KER32085.1 - 0.0011 18.8 0.5 14 5.4 0.0 4.7 6 0 0 6 6 5 0 Cytidylate kinase AAA_3 PF07726.11 KER32085.1 - 0.0015 18.4 0.1 61 3.5 0.0 5.5 6 0 0 6 6 6 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KER32085.1 - 0.0022 17.7 0.7 0.41 10.3 0.0 4.6 6 0 0 6 6 6 1 Thymidylate kinase MobB PF03205.14 KER32085.1 - 0.0041 17.0 4.9 70 3.3 0.0 6.0 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.17 KER32085.1 - 0.0066 15.6 0.3 68 2.4 0.0 4.9 5 0 0 5 5 5 0 Parvovirus non-structural protein NS1 CPT PF07931.12 KER32085.1 - 0.014 15.2 0.0 31 4.3 0.0 4.3 5 0 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein RET_CLD4 PF17813.1 KER32085.1 - 0.018 15.3 0.6 11 6.4 0.0 4.5 5 2 2 7 7 3 0 RET Cadherin like domain 4 Septin PF00735.18 KER32085.1 - 0.038 13.3 0.1 31 3.7 0.0 4.2 5 0 0 5 5 5 0 Septin TIP49 PF06068.13 KER32085.1 - 0.057 12.6 0.0 34 3.5 0.0 4.2 5 0 0 5 5 5 0 TIP49 P-loop domain DnaB_C PF03796.15 KER32085.1 - 0.16 11.3 0.0 65 2.7 0.0 4.3 6 0 0 6 6 6 0 DnaB-like helicase C terminal domain RsgA_GTPase PF03193.16 KER32085.1 - 0.19 11.6 0.0 1e+02 2.8 0.0 4.5 6 0 0 6 6 5 0 RsgA GTPase ATPase PF06745.13 KER32085.1 - 0.48 9.7 5.6 1.2e+02 1.9 0.0 5.6 6 0 0 6 6 6 0 KaiC PPO1_DWL PF12142.8 KER32085.1 - 0.56 10.0 1.8 16 5.4 0.1 3.4 3 0 0 3 3 3 0 Polyphenol oxidase middle domain ADK PF00406.22 KER32086.1 - 2.3e-28 99.2 0.0 2.7e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KER32086.1 - 7.7e-12 45.8 0.0 9.6e-10 39.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KER32086.1 - 3e-10 40.4 0.0 2.5e-07 30.9 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KER32086.1 - 8.7e-05 23.1 0.0 0.0028 18.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KER32086.1 - 0.0061 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KER32086.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KER32086.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KER32086.1 - 0.012 15.7 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KER32086.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KER32086.1 - 0.028 14.3 0.2 0.43 10.4 0.0 2.5 3 0 0 3 3 3 0 Deoxynucleoside kinase RNA_helicase PF00910.22 KER32086.1 - 0.13 12.7 0.3 0.8 10.1 0.1 2.4 2 1 0 2 2 2 0 RNA helicase G-alpha PF00503.20 KER32086.1 - 0.14 11.3 0.4 0.26 10.4 0.1 1.7 2 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KER32086.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tim17 PF02466.19 KER32087.1 - 8.9e-14 51.8 0.9 1.4e-13 51.2 0.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family GIY-YIG PF01541.24 KER32089.1 - 0.024 14.9 0.1 0.036 14.4 0.1 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain zf-C2H2 PF00096.26 KER32089.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_UL49_2 PF04823.12 KER32089.1 - 0.16 12.1 0.1 5.2 7.2 0.0 2.3 2 1 0 2 2 2 0 Herpesvirus UL49 tegument protein EF-hand_6 PF13405.6 KER32090.1 - 2.3e-15 55.1 4.4 0.00077 19.2 0.0 5.0 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KER32090.1 - 1.9e-13 50.7 2.2 3.1e-08 34.0 0.4 3.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KER32090.1 - 6.8e-09 34.7 6.5 0.0074 15.8 0.0 4.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KER32090.1 - 0.00018 21.3 4.1 0.037 13.9 0.3 4.4 3 1 2 5 5 5 1 EF-hand domain pair DevR PF01905.16 KER32090.1 - 0.0056 15.8 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 2 CRISPR-associated negative auto-regulator DevR/Csa2 EF-hand_9 PF14658.6 KER32090.1 - 0.015 15.6 0.9 5.3 7.4 0.1 3.9 3 1 1 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 KER32090.1 - 0.083 12.4 8.1 2.3 7.8 0.0 3.8 6 0 0 6 6 6 0 EF hand Toxin_23 PF08093.11 KER32090.1 - 0.11 12.6 5.0 5.7 7.2 0.4 2.3 2 0 0 2 2 2 0 Magi 5 toxic peptide family EHD_N PF16880.5 KER32090.1 - 0.11 12.4 0.7 25 4.8 0.1 2.8 2 0 0 2 2 2 0 N-terminal EH-domain containing protein Caleosin PF05042.13 KER32090.1 - 0.15 12.0 0.7 1.6 8.6 0.1 2.8 3 1 0 3 3 3 0 Caleosin related protein Cadherin PF00028.17 KER32094.1 - 2e-64 214.1 3.2 6e-16 58.7 0.1 9.4 7 2 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER32094.1 - 6.1e-09 35.6 0.1 0.019 14.8 0.1 5.4 5 1 0 5 5 5 3 Cadherin-like Cadherin_3 PF16184.5 KER32094.1 - 2.9e-06 27.2 9.8 2.1 8.4 0.2 6.8 7 0 0 7 7 7 3 Cadherin-like Synaphin PF05835.12 KER32097.1 - 2.2e-44 151.2 10.2 2.6e-44 150.9 10.2 1.0 1 0 0 1 1 1 1 Synaphin protein OmpH PF03938.14 KER32097.1 - 0.092 13.1 4.9 0.12 12.7 4.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SpecificRecomb PF10136.9 KER32097.1 - 0.18 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF4407 PF14362.6 KER32097.1 - 0.86 8.9 4.3 0.98 8.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA_bind_2 PF13725.6 KER32097.1 - 7.5 6.2 7.7 0.93 9.1 2.8 1.7 2 0 0 2 2 2 0 Possible tRNA binding domain HEPPP_synt_1 PF07307.11 KER32098.1 - 0.0023 17.6 1.1 1.7 8.2 0.1 2.1 2 0 0 2 2 2 2 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Nuc_H_symport PF03825.16 KER32098.1 - 0.065 12.2 0.0 7.7 5.4 0.0 2.0 2 0 0 2 2 2 0 Nucleoside H+ symporter DUF5601 PF18151.1 KER32098.1 - 0.096 13.0 0.8 18 5.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) DUF5040 PF16443.5 KER32098.1 - 0.17 11.2 0.0 20 4.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5040) Caerin_1 PF07440.12 KER32098.1 - 0.25 11.5 1.8 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Caerin 1 protein DUF5553 PF17707.1 KER32098.1 - 2.1 7.8 9.7 3.7 6.9 0.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5553) HJURP_C PF12347.8 KER32098.1 - 9.8 6.3 7.9 24 5.0 0.9 2.4 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat FAD_binding_4 PF01565.23 KER32099.1 - 0.0018 18.0 0.3 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain LID PF17916.1 KER32100.1 - 6.8e-18 64.0 1.7 1.6e-17 62.9 1.7 1.7 1 0 0 1 1 1 1 LIM interaction domain (LID) LIM_bind PF01803.16 KER32100.1 - 5.1e-10 39.3 1.8 9.9e-10 38.4 0.0 2.3 3 0 0 3 3 3 1 LIM-domain binding protein RVT_1 PF00078.27 KER32101.1 - 1.7e-11 44.1 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FNIP_C PF14638.6 KER32101.1 - 7.7e-08 32.2 0.0 7.5e-07 29.0 0.0 2.5 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_M PF14637.6 KER32101.1 - 2.3e-05 24.5 0.0 0.00026 21.1 0.0 2.2 1 1 0 1 1 1 1 Folliculin-interacting protein middle domain DENN PF02141.21 KER32103.1 - 4.9e-32 111.4 4.6 1.4e-31 109.9 4.6 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KER32103.1 - 2.1e-20 73.2 0.8 8.8e-20 71.2 0.8 2.2 1 0 0 1 1 1 1 uDENN domain G-alpha PF00503.20 KER32107.1 - 1.9e-27 96.4 1.2 3.6e-27 95.5 1.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KER32107.1 - 0.0042 16.5 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER32107.1 - 0.0079 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1158 PF06643.11 KER32108.1 - 0.18 12.3 0.0 18 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) ATP-synt_ab PF00006.25 KER32110.1 - 1.5e-62 211.0 0.0 2.1e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KER32110.1 - 2.1e-21 76.2 0.9 4.3e-21 75.2 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KER32110.1 - 0.0089 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 KER32110.1 - 0.041 13.1 0.7 0.064 12.4 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 KER32110.1 - 0.07 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KER32110.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KER32110.1 - 0.092 13.1 0.1 0.28 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KER32110.1 - 0.094 13.0 0.5 0.27 11.6 0.2 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KER32110.1 - 0.22 11.4 0.3 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF4801 PF16059.5 KER32113.1 - 0.12 12.4 2.2 0.31 11.0 2.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4801) LRR_8 PF13855.6 KER32119.1 - 2.6e-25 87.9 15.9 2.3e-11 43.3 0.2 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KER32119.1 - 2.9e-13 49.7 7.3 0.00016 22.0 0.6 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER32119.1 - 4.6e-10 38.6 12.9 0.07 13.7 0.0 7.3 6 0 0 6 6 6 2 Leucine Rich Repeat I-set PF07679.16 KER32119.1 - 2e-06 27.8 0.0 4.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER32119.1 - 4.8e-06 27.1 0.3 2.9e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 KER32119.1 - 7.9e-06 26.0 0.1 1.5e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER32119.1 - 5.1e-05 23.5 0.0 0.00016 21.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 KER32119.1 - 0.002 17.6 1.1 0.008 15.7 0.9 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRRCT PF01463.24 KER32119.1 - 0.0043 17.5 0.2 0.017 15.6 0.2 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Shisa PF13908.6 KER32119.1 - 0.0088 16.3 0.7 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator V-set PF07686.17 KER32119.1 - 0.025 14.7 0.3 0.65 10.2 0.3 2.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain C1-set PF07654.15 KER32119.1 - 0.13 12.6 0.2 0.29 11.5 0.2 1.5 1 0 0 1 1 1 0 Immunoglobulin C1-set domain LRR_6 PF13516.6 KER32119.1 - 0.38 10.9 22.4 2 8.7 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich repeat ASC PF00858.24 KER32121.1 - 1.6e-18 66.9 0.0 1.3e-16 60.7 0.0 2.5 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3918 PF13056.6 KER32123.1 - 0.0049 16.4 1.3 1.7 8.3 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3918) PHD PF00628.29 KER32125.1 - 1.8e-08 34.1 3.1 1.8e-08 34.1 3.1 2.9 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KER32125.1 - 7e-08 32.6 0.0 7e-08 32.6 0.0 3.4 4 1 1 5 5 5 1 PHD-zinc-finger like domain PHD_2 PF13831.6 KER32125.1 - 3.2e-05 23.4 6.2 0.00021 20.8 6.2 2.4 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KER32125.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HILPDA PF15220.6 KER32125.1 - 0.08 13.1 0.5 12 6.1 0.1 2.6 1 1 1 2 2 2 0 Hypoxia-inducible lipid droplet-associated ZapB PF06005.12 KER32125.1 - 0.16 12.4 1.8 20 5.7 0.0 3.0 2 1 0 2 2 2 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 KER32125.1 - 0.45 10.5 1.9 0.62 10.1 0.6 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-PHD-like PF15446.6 KER32125.1 - 0.64 9.6 4.0 0.34 10.5 0.8 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KER32125.1 - 7.8 6.7 14.9 0.18 12.0 4.7 3.3 3 1 0 3 3 3 0 PHD-finger DUF775 PF05603.12 KER32126.1 - 5.1e-43 146.9 0.0 9.1e-43 146.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DnaJ PF00226.31 KER32127.1 - 1e-17 64.0 2.4 2.5e-17 62.7 2.4 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 KER32128.1 - 9.3e-15 54.5 2.5 1.7e-14 53.7 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain MINDY_DUB PF04424.13 KER32129.1 - 1.8e-32 111.8 0.0 4.9e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 MINDY deubiquitinase MeaB PF03308.16 KER32130.1 - 3.3e-81 272.2 0.2 3e-75 252.7 0.0 2.3 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KER32130.1 - 0.00014 21.5 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KER32130.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KER32130.1 - 0.024 15.2 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KER32130.1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KER32130.1 - 0.11 12.7 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KER32130.1 - 0.11 12.5 0.0 0.43 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KER32130.1 - 0.18 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GHMP_kinases_N PF00288.26 KER32132.1 - 2.4e-16 59.7 0.2 5.8e-16 58.5 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KER32132.1 - 3.9e-12 46.4 0.0 8.5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KER32132.1 - 3.8e-05 23.2 0.1 8.7e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature zf-TRAF PF02176.18 KER32133.1 - 0.0008 20.1 4.5 0.0008 20.1 4.5 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger DUF2039 PF10217.9 KER32133.1 - 0.031 14.6 2.2 0.074 13.4 2.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf_UBZ PF18439.1 KER32133.1 - 1 9.0 5.6 7.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger LNS2 PF08235.13 KER32137.1 - 3.4e-61 206.6 0.0 5.5e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KER32137.1 - 4.7e-30 103.6 0.0 8.1e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region WD40 PF00400.32 KER32138.1 - 4e-42 141.4 35.6 2.9e-07 31.0 0.3 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KER32138.1 - 2.2e-36 124.9 2.2 3.7e-36 124.1 2.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KER32138.1 - 1.4e-05 25.3 2.2 0.15 12.3 0.1 5.3 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER32138.1 - 0.025 13.2 2.4 0.54 8.8 0.0 3.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Pkinase PF00069.25 KER32139.1 - 3.3e-25 88.9 0.1 2.3e-14 53.4 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER32139.1 - 6.8e-11 41.9 0.2 0.00013 21.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KER32139.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HA2 PF04408.23 KER32140.1 - 3.8e-24 85.0 0.2 3.8e-24 85.0 0.2 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KER32140.1 - 3.6e-22 78.5 0.0 8.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KER32140.1 - 1.2e-11 44.9 0.0 2.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER32140.1 - 1e-07 31.9 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KER32140.1 - 0.0005 20.4 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER32140.1 - 0.00076 19.8 0.1 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KER32140.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KER32140.1 - 0.003 18.1 0.0 0.018 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KER32140.1 - 0.013 15.1 0.1 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KER32140.1 - 0.015 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KER32140.1 - 0.034 13.9 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KER32140.1 - 0.054 14.0 0.2 0.2 12.2 0.2 1.9 1 1 1 2 2 2 0 ABC transporter NACHT PF05729.12 KER32140.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain HTH_IclR PF09339.10 KER32140.1 - 0.089 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain AAA_7 PF12775.7 KER32140.1 - 0.14 11.7 0.1 0.66 9.5 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region Ig_3 PF13927.6 KER32141.1 - 1.2e-41 141.1 1.1 1.1e-11 45.1 0.0 6.6 6 1 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 KER32141.1 - 1.1e-30 105.5 0.0 1.3e-11 44.4 0.0 5.8 5 1 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KER32141.1 - 2.1e-23 82.5 0.1 1.4e-05 25.3 0.0 6.1 6 1 0 6 6 6 5 Immunoglobulin domain ig PF00047.25 KER32141.1 - 5.1e-22 77.9 0.2 4.9e-07 29.8 0.0 5.6 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 KER32141.1 - 1.1e-17 64.2 4.8 2.3e-10 40.6 0.2 5.1 4 2 1 5 5 5 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER32141.1 - 8.2e-11 41.8 0.1 0.028 14.5 0.0 5.5 5 1 0 5 5 5 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KER32141.1 - 0.0042 17.4 0.3 0.89 10.0 0.0 4.2 4 1 0 4 4 4 1 Immunoglobulin C1-set domain Ig_6 PF18452.1 KER32141.1 - 0.0084 15.7 0.0 3.4 7.3 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain HTH_30 PF13556.6 KER32142.1 - 0.13 12.1 3.2 3.1 7.7 0.1 2.4 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain RRM_1 PF00076.22 KER32143.1 - 2.3e-59 197.1 0.0 3.3e-19 68.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER32143.1 - 1.7e-10 40.5 0.0 6.1e-05 22.6 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER32143.1 - 6.6e-05 22.7 0.0 0.00027 20.8 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KER32143.1 - 0.087 12.8 0.0 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif HEPN_RnaseLS PF18869.1 KER32144.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 RnaseLS-like HEPN cNMP_binding PF00027.29 KER32146.1 - 5.3e-12 45.7 0.0 0.00041 20.4 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DUF3136 PF11334.8 KER32147.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Stress-antifung PF01657.17 KER32147.1 - 0.12 13.0 1.1 0.32 11.7 1.1 1.9 1 1 0 1 1 1 0 Salt stress response/antifungal PCRF PF03462.18 KER32148.1 - 2.4e-43 148.3 0.0 4.8e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KER32148.1 - 1.5e-37 128.0 0.4 3.4e-37 126.9 0.4 1.6 1 0 0 1 1 1 1 RF-1 domain MORN PF02493.20 KER32149.1 - 7.3e-26 88.5 41.9 1.1e-06 28.2 2.8 7.1 8 0 0 8 8 8 6 MORN repeat DUF4028 PF13220.6 KER32149.1 - 0.055 13.2 0.8 0.22 11.3 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) LEM PF03020.15 KER32150.1 - 1.8e-15 56.2 0.3 1.8e-15 56.2 0.3 2.1 2 0 0 2 2 2 1 LEM domain MSC PF09402.10 KER32150.1 - 8.8e-12 45.1 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain CoA_binding_3 PF13727.6 KER32150.1 - 0.063 13.3 0.4 0.063 13.3 0.4 1.6 2 0 0 2 2 2 0 CoA-binding domain COE1_HLH PF16423.5 KER32150.1 - 0.14 11.8 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain RseA_N PF03872.13 KER32152.1 - 0.21 12.1 1.4 0.53 10.8 0.3 1.9 2 0 0 2 2 2 0 Anti sigma-E protein RseA, N-terminal domain MULE PF10551.9 KER32153.1 - 2.4e-21 75.9 0.0 7.2e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain LrgB PF04172.16 KER32153.1 - 0.0021 17.6 1.5 0.0021 17.6 1.5 1.7 2 0 0 2 2 2 1 LrgB-like family SWIM PF04434.17 KER32153.1 - 0.11 12.2 0.8 0.33 10.7 0.8 1.8 1 0 0 1 1 1 0 SWIM zinc finger Tmemb_185A PF10269.9 KER32153.1 - 0.88 9.2 14.7 4.4 6.9 13.7 1.9 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein WD40 PF00400.32 KER32155.1 - 1.7e-32 110.9 33.2 2.1e-06 28.3 0.1 8.4 9 1 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 KER32155.1 - 7.8e-11 41.7 3.4 2.8e-10 39.9 3.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KER32155.1 - 0.00022 21.0 4.3 0.00047 20.0 0.4 2.8 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 KER32155.1 - 0.036 13.4 0.2 4.4 6.5 0.4 2.9 3 0 0 3 3 3 0 WD40-like domain ANAPC4_WD40 PF12894.7 KER32155.1 - 0.081 13.2 1.6 4.6 7.6 0.1 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER32155.1 - 0.13 10.9 14.9 3.1 6.3 2.3 4.1 2 1 1 4 4 4 0 Nucleoporin Nup120/160 BTB PF00651.31 KER32158.1 - 1.4e-25 89.7 0.9 3.1e-25 88.5 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 KER32158.1 - 9.8e-07 28.9 0.0 3.4e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 KER32158.1 - 0.00047 20.2 0.4 0.0065 16.6 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Transferrin PF00405.17 KER32159.1 - 7.6e-118 393.4 0.0 2.7e-76 256.9 0.0 2.1 2 0 0 2 2 2 2 Transferrin Sec8_exocyst PF04048.14 KER32160.1 - 1.2e-06 28.4 1.0 3.1e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Pkinase_Tyr PF07714.17 KER32162.1 - 6.3e-89 297.7 0.0 9.2e-89 297.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER32162.1 - 2.4e-44 151.7 0.0 4.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 KER32162.1 - 1.6e-27 95.4 2.4 7.6e-15 54.8 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 KER32162.1 - 1.9e-15 57.2 1.0 5.5e-10 39.7 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER32162.1 - 6.4e-14 51.7 4.4 0.0033 17.8 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KER32162.1 - 3.6e-12 46.5 1.2 2.5e-08 34.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32162.1 - 4.9e-11 41.9 3.6 0.016 15.7 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KER32162.1 - 1.5e-10 41.1 3.8 2.2e-06 27.8 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 KER32162.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER32162.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SH2 PF00017.24 KER32163.1 - 8e-27 93.2 2.6 4e-14 52.5 0.1 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 KER32163.1 - 5.2e-11 43.0 0.1 9.7e-07 29.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KER32163.1 - 4.9e-09 36.2 3.0 0.0066 16.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KER32163.1 - 3.2e-08 33.7 2.4 0.11 12.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER32163.1 - 7.9e-08 32.7 0.6 0.019 15.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32163.1 - 1.2e-06 28.4 4.5 0.026 15.1 0.1 4.9 5 0 0 5 5 5 2 Ankyrin repeat Pkinase_Tyr PF07714.17 KER32163.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 KER32164.1 - 5.8e-55 183.8 3.4 1.4e-13 51.2 0.0 6.6 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KER32164.1 - 7.3e-49 163.8 0.0 2.2e-11 43.6 0.0 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain ig PF00047.25 KER32164.1 - 4.2e-29 100.6 7.0 2e-07 31.1 0.0 6.1 6 0 0 6 6 6 4 Immunoglobulin domain Ig_2 PF13895.6 KER32164.1 - 4.1e-28 97.5 2.1 1.3e-06 28.7 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KER32164.1 - 1.8e-20 73.1 2.4 0.0013 18.9 0.0 6.7 4 3 1 5 5 5 5 Immunoglobulin V-set domain Ig_6 PF18452.1 KER32164.1 - 9.2e-12 44.3 0.1 0.028 14.0 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain fn3 PF00041.21 KER32164.1 - 3.6e-11 43.2 8.3 0.00033 21.0 2.0 5.8 6 1 0 6 6 6 2 Fibronectin type III domain C2-set_2 PF08205.12 KER32164.1 - 3.5e-06 27.0 0.1 0.46 10.6 0.0 4.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 KER32164.1 - 0.0011 18.9 0.0 2.3 8.3 0.0 4.1 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 KER32164.1 - 0.016 15.8 0.6 0.15 12.7 0.1 2.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3_4 PF16794.5 KER32164.1 - 0.037 13.9 0.1 5.3 7.0 0.0 2.8 2 1 0 2 2 2 0 Fibronectin-III type domain fn3_2 PF16893.5 KER32164.1 - 0.13 12.5 0.2 0.71 10.1 0.2 2.3 2 0 0 2 2 1 0 Fibronectin type III domain Ig_C17orf99 PF17736.1 KER32164.1 - 0.66 10.1 7.2 13 5.9 0.0 4.5 5 1 0 5 5 5 0 C17orf99 Ig domain Ig_3 PF13927.6 KER32166.1 - 1.9e-57 191.8 0.9 5.4e-12 46.1 0.0 6.9 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 KER32166.1 - 3.8e-49 164.7 0.0 3.6e-15 55.8 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 KER32166.1 - 2.8e-28 98.0 0.2 0.00014 22.1 0.0 6.0 4 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 KER32166.1 - 1.7e-27 95.4 0.1 1.1e-06 28.7 0.0 5.8 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 KER32166.1 - 3.8e-26 91.4 1.7 1.5e-05 25.1 0.0 7.4 6 3 1 7 7 7 4 Immunoglobulin V-set domain Ig_6 PF18452.1 KER32166.1 - 5.1e-13 48.4 0.0 0.0036 16.8 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.21 KER32166.1 - 3.1e-12 46.7 2.5 0.045 14.1 0.0 6.9 7 0 0 7 7 7 2 Fibronectin type III domain C2-set_2 PF08205.12 KER32166.1 - 2.1e-08 34.1 0.0 0.19 11.8 0.0 4.4 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KER32166.1 - 0.00022 21.6 0.0 4.5 7.7 0.0 4.8 6 0 0 6 6 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_C17orf99 PF17736.1 KER32166.1 - 0.018 15.1 0.0 15 5.7 0.0 3.9 4 0 0 4 4 4 0 C17orf99 Ig domain fn3_2 PF16893.5 KER32166.1 - 0.024 14.8 0.2 16 5.7 0.2 3.2 3 0 0 3 3 3 0 Fibronectin type III domain Receptor_2B4 PF11465.8 KER32166.1 - 0.032 14.4 0.3 25 5.1 0.0 4.1 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 Epiglycanin_C PF14654.6 KER32166.1 - 0.053 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region PRIMA1 PF16101.5 KER32166.1 - 7.4 6.6 7.7 22 5.1 0.1 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 wnt PF00110.19 KER32167.1 - 1.6e-72 244.7 1.4 8.7e-40 137.2 0.4 2.1 2 0 0 2 2 2 2 wnt family NDUFA12 PF05071.16 KER32170.1 - 2e-27 95.9 5.0 2.5e-27 95.5 5.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SBDS_C PF09377.10 KER32171.1 - 5e-29 100.7 0.5 8e-29 100.0 0.5 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KER32171.1 - 5.8e-22 77.6 1.1 6.1e-21 74.3 1.1 2.4 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MRP-S28 PF10213.9 KER32171.1 - 0.046 14.1 0.1 0.1 13.0 0.1 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit protein PcF PF09461.10 KER32174.1 - 0.0098 16.2 0.1 0.0098 16.2 0.1 2.3 2 0 0 2 2 2 1 Phytotoxin PcF protein XPG_I_2 PF12813.7 KER32175.1 - 1.6 8.1 4.5 12 5.3 0.3 2.1 1 1 1 2 2 2 0 XPG domain containing Mito_carr PF00153.27 KER32177.1 - 5.6e-82 269.8 7.3 9.1e-24 83.2 0.0 5.8 4 2 1 5 5 5 5 Mitochondrial carrier protein EF-hand_7 PF13499.6 KER32177.1 - 2.2e-13 50.4 5.1 6.7e-05 23.3 2.4 4.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KER32177.1 - 2.9e-13 48.3 2.7 0.016 14.7 0.3 5.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KER32177.1 - 2.5e-11 42.5 2.0 0.044 13.7 0.0 5.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KER32177.1 - 8.2e-09 35.2 1.7 0.0092 15.8 0.0 4.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KER32177.1 - 1.3e-05 24.5 1.7 0.066 12.7 0.0 4.6 4 0 0 4 4 4 2 EF hand Ig_mannosidase PF17753.1 KER32178.1 - 2.1e-06 27.4 0.1 5.4e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KER32178.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KER32178.1 - 0.0044 17.7 0.0 0.0094 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Homeodomain PF00046.29 KER32179.1 - 1e-20 73.3 5.5 1e-20 73.3 5.5 2.3 3 0 0 3 3 3 1 Homeodomain Tti2 PF10521.9 KER32181.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Tti2 family fn3 PF00041.21 KER32183.1 - 1.3e-14 54.3 12.3 1e-06 29.0 0.0 6.8 6 1 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER32183.1 - 0.021 15.4 2.3 0.66 10.6 0.7 3.5 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Y_phosphatase PF00102.27 KER32184.1 - 5e-56 189.9 0.0 7.4e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KER32184.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KER32184.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KER32184.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TAFII55_N PF04658.13 KER32186.1 - 1.4e-51 174.4 0.1 1.9e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 TAFII55 protein conserved region Sod_Cu PF00080.20 KER32191.1 - 2e-36 125.3 1.4 2.7e-36 124.9 1.4 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Asp PF00026.23 KER32192.1 - 1.5e-16 60.8 0.0 4.6e-11 42.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KER32192.1 - 0.099 13.2 0.0 3.9 8.1 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER32192.1 - 0.18 12.5 0.0 5.5 7.7 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KER32193.1 - 0.00074 19.0 0.0 0.009 15.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 KER32194.1 - 2.3e-10 40.4 0.0 3.5e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 KER32195.1 - 7e-18 65.1 0.0 9.2e-12 45.0 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KER32195.1 - 0.011 16.3 0.0 0.71 10.5 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KER32195.1 - 0.034 14.7 0.0 0.4 11.3 0.0 2.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KER32195.1 - 0.039 13.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Enolase_C PF00113.22 KER32199.1 - 6.9e-09 35.4 0.0 7.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain She2p PF11435.8 KER32199.1 - 0.073 12.7 0.3 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 RNA binding protein She2p SYF2 PF08231.12 KER32200.1 - 1.3e-43 149.1 12.9 1.3e-43 149.1 12.9 1.5 2 0 0 2 2 2 1 SYF2 splicing factor Gpi1 PF05024.15 KER32201.1 - 1e-21 77.9 9.6 6.8e-20 71.9 9.6 2.7 1 1 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Aa_trans PF01490.18 KER32203.1 - 2.9e-38 131.7 27.9 3.6e-38 131.4 27.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM247 PF15444.6 KER32203.1 - 1.3 9.0 2.9 1.7 8.7 1.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 247 p25-alpha PF05517.12 KER32204.1 - 8.5e-37 126.7 3.2 1e-36 126.4 3.2 1.0 1 0 0 1 1 1 1 p25-alpha DNA_pol_B PF00136.21 KER32205.1 - 1.1e-58 199.1 0.0 3.3e-57 194.2 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KER32205.1 - 2.9e-08 33.2 0.0 3.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain HNOBA PF07701.14 KER32209.1 - 3.6e-57 193.3 2.7 1.5e-56 191.3 2.7 2.0 1 1 0 1 1 1 1 Heme NO binding associated HNOB PF07700.15 KER32209.1 - 3.2e-49 167.0 0.0 5.4e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Haem-NO-binding Guanylate_cyc PF00211.20 KER32209.1 - 6.1e-49 166.1 0.0 9.3e-49 165.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain KIP1 PF07765.12 KER32209.1 - 4.8 7.4 5.9 2.4 8.3 0.5 3.0 4 0 0 4 4 4 0 KIP1-like protein Ribosomal_L30 PF00327.20 KER32210.1 - 6.6e-20 70.8 0.8 1.8e-19 69.3 0.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 KER32210.1 - 2e-13 50.3 12.0 4.3e-13 49.3 12.0 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Tubulin PF00091.25 KER32211.1 - 7.2e-66 222.1 0.0 1.1e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER32211.1 - 1.6e-41 141.4 0.0 2.9e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER32211.1 - 0.00033 20.9 0.0 0.0009 19.5 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Ank PF00023.30 KER32215.1 - 3.5e-22 77.8 2.8 2.3e-09 37.3 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 KER32215.1 - 1.5e-19 70.3 0.2 2.5e-15 56.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER32215.1 - 1.6e-19 70.0 4.6 5.5e-11 42.8 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER32215.1 - 3.5e-19 68.6 5.4 2e-09 37.5 0.1 3.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32215.1 - 5.8e-17 60.1 0.3 0.0003 21.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat ADAM_CR_2 PF17771.1 KER32216.1 - 3.5e-15 56.3 27.5 2.8e-13 50.2 7.1 3.8 2 1 1 3 3 3 2 ADAM cysteine-rich domain Reprolysin PF01421.19 KER32216.1 - 1.2e-14 54.7 0.2 1.9e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 KER32216.1 - 7.5e-09 36.0 1.3 2e-08 34.6 1.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KER32216.1 - 8.5e-07 28.8 0.1 1.4e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KER32216.1 - 8.2e-05 22.6 0.4 0.00014 21.8 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KER32216.1 - 8.2e-05 23.1 0.1 0.00017 22.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 KER32216.1 - 0.00017 21.7 5.0 0.00017 21.7 5.0 3.4 3 0 0 3 3 3 1 Thrombospondin type 1 domain DUF3152 PF11350.8 KER32216.1 - 0.068 12.9 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) ApeC PF16977.5 KER32217.1 - 1.9e-46 158.6 1.1 8.4e-21 74.9 0.1 7.4 3 1 3 7 7 7 5 C-terminal domain of apextrin Kringle PF00051.18 KER32217.1 - 4.2e-29 100.7 19.8 3.5e-14 52.9 7.2 3.0 2 0 0 2 2 2 2 Kringle domain EGF_3 PF12947.7 KER32217.1 - 0.0017 18.5 50.5 0.0042 17.2 4.5 5.5 5 0 0 5 5 5 3 EGF domain DUF687 PF05095.12 KER32217.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) cEGF PF12662.7 KER32217.1 - 0.42 10.6 46.0 0.42 10.6 2.8 7.5 7 0 0 7 7 7 0 Complement Clr-like EGF-like 3A PF00803.18 KER32218.1 - 0.0046 16.3 0.0 0.0054 16.1 0.0 1.0 1 0 0 1 1 1 1 3A/RNA2 movement protein family zf-CCCH PF00642.24 KER32219.1 - 4.8e-15 55.0 4.3 2.3e-08 33.8 0.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER32219.1 - 7.9e-06 25.7 5.3 0.0013 18.7 0.5 2.3 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KER32219.1 - 0.47 11.2 6.0 7.4 7.3 0.5 2.2 1 1 1 2 2 2 0 Torus domain SNARE PF05739.19 KER32220.1 - 1.2e-13 50.9 2.6 1.2e-13 50.9 2.6 1.8 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 KER32220.1 - 0.00025 19.2 1.5 0.00031 18.9 1.5 1.0 1 0 0 1 1 1 1 Prominin Syntaxin PF00804.25 KER32220.1 - 0.0021 17.8 0.8 0.0021 17.8 0.8 1.7 2 0 0 2 2 2 1 Syntaxin I_LWEQ PF01608.17 KER32220.1 - 0.0096 16.2 1.3 0.11 12.7 0.3 2.1 2 0 0 2 2 2 1 I/LWEQ domain pP_pnuc_1 PF18165.1 KER32220.1 - 0.01 15.8 0.5 0.014 15.3 0.3 1.4 1 1 0 1 1 1 0 Predicted pPIWI-associating nuclease Vac7 PF12751.7 KER32220.1 - 0.013 15.0 0.6 0.019 14.4 0.6 1.3 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 ETRAMP PF09716.10 KER32220.1 - 0.049 13.7 1.1 0.063 13.3 1.1 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.11 KER32220.1 - 0.1 12.5 1.7 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 LXG PF04740.12 KER32220.1 - 0.14 11.9 4.1 0.2 11.4 2.6 1.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily HMG_box PF00505.19 KER32221.1 - 3.2e-19 69.1 1.3 6.6e-19 68.1 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KER32221.1 - 9.5e-08 32.5 0.8 2.1e-07 31.5 0.8 1.5 1 0 0 1 1 1 1 HMG-box domain zf-CW PF07496.15 KER32226.1 - 0.38 10.8 2.3 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 CW-type Zinc Finger GST_N_3 PF13417.6 KER32227.1 - 2.6e-17 63.0 0.0 5.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER32227.1 - 3.6e-14 52.8 0.1 8.4e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KER32227.1 - 6.4e-11 42.4 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KER32227.1 - 7.9e-09 35.6 0.0 2.3e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER32227.1 - 1.4e-07 31.4 0.0 4.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KER32227.1 - 1.7e-07 31.4 0.0 4.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KER32227.1 - 0.0006 19.6 0.2 0.0021 17.8 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KER32227.1 - 0.00096 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 KER32227.1 - 0.0085 16.8 0.0 0.024 15.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KER32227.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Glutaredoxin2_C PF04399.13 KER32227.1 - 0.13 12.1 0.0 0.53 10.1 0.0 1.9 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain RT_RNaseH_2 PF17919.1 KER32228.1 - 0.00031 20.7 0.2 0.0058 16.6 0.1 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KER32228.1 - 0.0068 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SPT16 PF08644.11 KER32229.1 - 1.7e-54 184.1 0.1 1.7e-54 184.1 0.1 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KER32229.1 - 2.2e-39 134.8 0.0 4.8e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KER32229.1 - 1.2e-18 67.6 0.0 2.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KER32229.1 - 2.5e-13 50.3 0.3 1.1e-12 48.2 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Na_H_Exchanger PF00999.21 KER32232.1 - 6.7e-58 196.3 48.1 8.4e-58 196.0 48.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KER32233.1 - 1e-56 192.4 48.9 1.3e-56 192.0 48.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KER32236.1 - 2e-38 132.2 40.5 6.3e-22 77.9 17.5 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF4286 PF14114.6 KER32236.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) DUF2981 PF11200.8 KER32236.1 - 0.32 10.7 1.4 6.4 6.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) Na_H_Exchanger PF00999.21 KER32237.1 - 3e-58 197.5 49.6 3.8e-58 197.1 49.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KER32238.1 - 3.3e-55 187.4 38.9 4e-55 187.2 38.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3169 PF11368.8 KER32238.1 - 0.11 12.1 0.2 0.11 12.1 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) Na_H_Exchanger PF00999.21 KER32239.1 - 1.7e-36 125.9 29.8 3.2e-35 121.7 21.0 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family BrkDBD PF09607.10 KER32239.1 - 0.089 12.6 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Acid_PPase PF12689.7 KER32240.1 - 4.4e-37 127.5 0.0 7.6e-37 126.7 0.0 1.3 1 1 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 KER32240.1 - 0.042 13.9 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gag_p6 PF08705.11 KER32242.1 - 0.075 13.3 4.3 0.13 12.5 4.3 1.5 1 0 0 1 1 1 0 Gag protein p6 Sec23_trunk PF04811.15 KER32243.1 - 2.2e-64 217.3 0.0 3.1e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KER32243.1 - 1.4e-20 73.0 0.0 3.2e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KER32243.1 - 1.9e-16 60.6 0.0 3.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KER32243.1 - 8.8e-15 54.5 0.7 2e-14 53.4 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KER32243.1 - 6e-11 42.1 0.0 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat TcdA_TcdB PF12919.7 KER32244.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Ras PF00071.22 KER32245.1 - 1.7e-24 86.2 0.1 1.4e-15 57.3 0.0 2.1 1 1 1 2 2 2 2 Ras family FeoB_N PF02421.18 KER32245.1 - 0.0027 17.2 0.0 0.13 11.8 0.0 2.1 1 1 1 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KER32245.1 - 0.023 14.6 0.0 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase IMPa_N_2 PF18650.1 KER32245.1 - 0.037 13.3 0.2 4.7 6.4 0.0 2.1 1 1 1 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Roc PF08477.13 KER32245.1 - 0.074 13.3 0.0 17 5.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Adipokin_hormo PF06377.11 KER32245.1 - 0.092 13.1 0.0 11 6.4 0.0 2.3 1 1 1 2 2 2 0 Adipokinetic hormone Adeno_E1B_55K PF01696.17 KER32247.1 - 0.02 13.6 0.2 0.033 12.9 0.2 1.3 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen GIY-YIG PF01541.24 KER32248.1 - 0.14 12.4 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain ELM2 PF01448.24 KER32250.1 - 0.00063 20.4 0.0 0.0033 18.1 0.0 2.3 1 0 0 1 1 1 1 ELM2 domain DUF1296 PF06972.11 KER32250.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) NDK PF00334.19 KER32252.1 - 2.2e-53 179.9 0.0 2.5e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CBM39 PF15886.5 KER32253.1 - 0.096 12.6 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate binding domain (family 32) Glyco_transf_8 PF01501.20 KER32254.1 - 0.00087 18.9 0.2 0.02 14.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 KER32255.1 - 8.3e-06 25.5 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 Ldl_recept_a PF00057.18 KER32257.1 - 1.7e-34 117.7 57.6 4.8e-08 33.1 2.9 6.5 6 0 0 6 6 6 6 Low-density lipoprotein receptor domain class A GldM_C PF12080.8 KER32257.1 - 5.4e-05 23.5 0.2 13 5.9 0.0 4.1 4 0 0 4 4 4 3 GldM C-terminal domain RINGv PF12906.7 KER32258.1 - 3.9e-16 58.9 5.6 8.3e-16 57.8 5.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KER32258.1 - 0.0015 18.8 3.8 0.0047 17.2 3.8 1.9 1 0 0 1 1 1 1 Ring finger domain DUF4381 PF14316.6 KER32258.1 - 0.093 13.0 1.0 0.21 11.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-C3HC4 PF00097.25 KER32258.1 - 0.14 12.0 2.0 0.53 10.2 2.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER32258.1 - 0.65 9.9 3.4 2.1 8.3 3.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SLY PF12485.8 KER32260.1 - 0.0084 16.8 4.5 0.0092 16.7 1.2 2.6 2 1 0 2 2 2 1 Lymphocyte signaling adaptor protein Perilipin PF03036.16 KER32260.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Perilipin family CDC45 PF02724.14 KER32261.1 - 0.051 11.9 8.5 0.048 11.9 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER32261.1 - 0.11 10.7 14.6 0.11 10.7 14.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KER32261.1 - 0.22 9.6 27.1 0.25 9.4 27.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KER32261.1 - 4.1 6.7 19.7 4.7 6.5 19.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER32261.1 - 4.2 6.6 15.2 4.3 6.6 15.2 1.0 1 0 0 1 1 1 0 BUD22 ASC PF00858.24 KER32263.1 - 8e-57 193.2 2.2 1.9e-56 191.9 2.2 1.6 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel adh_short_C2 PF13561.6 KER32264.1 - 2.4e-42 145.1 0.6 7.6e-25 87.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KER32264.1 - 2e-32 112.3 4.2 7.2e-21 74.5 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KER32264.1 - 6.2e-08 32.8 0.1 6.2e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KER32264.1 - 1.6e-05 24.2 0.7 2e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KER32264.1 - 0.0094 16.4 0.1 0.019 15.4 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KER32264.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KER32264.1 - 0.03 13.3 0.2 0.049 12.6 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KER32264.1 - 0.03 13.8 0.2 0.055 12.9 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KER32264.1 - 0.051 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 KER32264.1 - 0.072 13.7 0.2 0.15 12.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CodY PF06018.14 KER32264.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 1 0 1 1 1 0 CodY GAF-like domain Taxilin PF09728.9 KER32265.1 - 3.9e-77 259.4 62.1 5e-77 259.1 62.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein ZapB PF06005.12 KER32265.1 - 0.017 15.5 8.9 0.017 15.5 8.9 5.7 1 1 3 4 4 4 0 Cell division protein ZapB Laminin_II PF06009.12 KER32265.1 - 0.049 13.7 31.3 0.26 11.3 1.0 4.2 1 1 2 4 4 4 0 Laminin Domain II Filament PF00038.21 KER32265.1 - 0.21 11.2 54.1 0.3 10.6 14.1 3.6 1 1 2 3 3 3 0 Intermediate filament protein Phage_tail_APC PF16778.5 KER32265.1 - 0.24 11.3 3.8 6.7 6.7 0.1 3.6 2 1 0 2 2 2 0 Phage tail assembly chaperone protein DUF812 PF05667.11 KER32265.1 - 0.43 9.4 54.3 0.1 11.5 43.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF948 PF06103.11 KER32265.1 - 4.8 7.5 10.6 6.7 7.0 0.1 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CEP63 PF17045.5 KER32265.1 - 7.7 6.3 57.9 2 8.3 26.5 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Amino_oxidase PF01593.24 KER32266.1 - 2e-84 284.5 0.0 2.1e-34 119.6 0.0 4.1 3 1 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KER32266.1 - 3.1e-11 43.3 0.1 7.9e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KER32266.1 - 3.3e-06 26.9 0.5 6.9e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KER32266.1 - 7.3e-06 26.5 0.2 2.9e-05 24.6 0.2 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KER32266.1 - 1.2e-05 24.2 0.0 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KER32266.1 - 1.4e-05 24.4 0.1 3.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KER32266.1 - 5.5e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KER32266.1 - 0.00016 21.0 0.6 0.00031 20.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KER32266.1 - 0.00034 19.8 0.1 0.00054 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KER32266.1 - 0.00079 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KER32266.1 - 0.0011 18.4 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KER32266.1 - 0.012 14.8 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KER32266.1 - 0.057 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KER32266.1 - 0.15 12.1 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding YqjK PF13997.6 KER32266.1 - 0.16 12.2 0.1 0.46 10.8 0.0 1.8 2 0 0 2 2 1 0 YqjK-like protein Tospo_nucleocap PF01533.16 KER32266.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein Pro_isomerase PF00160.21 KER32268.1 - 1.4e-48 165.1 0.2 1.6e-48 164.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HTH_38 PF13936.6 KER32269.1 - 3.5e-07 29.9 0.0 7.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KER32269.1 - 4.7e-07 29.6 0.5 1.3e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Tc3 transposase HTH_23 PF13384.6 KER32269.1 - 0.0013 18.5 0.3 0.25 11.2 0.0 2.6 3 0 0 3 3 3 2 Homeodomain-like domain zf-C2H2 PF00096.26 KER32272.1 - 0.083 13.4 1.0 0.36 11.4 1.0 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type VWC PF00093.18 KER32272.1 - 2 8.8 9.0 0.094 13.0 1.7 2.3 2 1 1 3 3 3 0 von Willebrand factor type C domain zf-MIZ PF02891.20 KER32272.1 - 2.9 7.7 9.4 1.9 8.3 2.7 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Snf7 PF03357.21 KER32273.1 - 3.8e-35 121.0 15.3 7.1e-35 120.1 15.3 1.4 1 0 0 1 1 1 1 Snf7 EAP30 PF04157.16 KER32273.1 - 3.5e-33 114.8 2.3 9.6e-33 113.4 0.6 2.2 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KER32273.1 - 3.5e-13 49.5 0.0 7.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HTH_24 PF13412.6 KER32273.1 - 0.0052 16.3 0.2 0.013 15.1 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GerD PF17898.1 KER32273.1 - 0.14 12.2 3.2 0.34 10.9 3.2 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF773 PF05600.12 KER32273.1 - 1.3 7.7 12.5 2.2 6.9 12.5 1.3 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Exonuc_VII_L PF02601.15 KER32273.1 - 2.1 7.8 13.1 2.3 7.7 11.4 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DHHC PF01529.20 KER32274.1 - 2.2e-20 73.1 8.7 2.2e-20 73.1 8.7 3.5 3 1 0 3 3 3 2 DHHC palmitoyltransferase Asp PF00026.23 KER32276.1 - 1.5e-15 57.5 0.0 5.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.23 KER32277.1 - 3.1e-52 177.9 0.0 3.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER32277.1 - 2.8e-07 30.9 0.1 3.1e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KER32277.1 - 0.00054 19.8 0.1 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 KER32279.1 - 4.3e-22 78.9 0.1 4.8e-22 78.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER32279.1 - 5.5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal I-set PF07679.16 KER32281.1 - 2.7e-17 62.6 0.0 3e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER32281.1 - 5.9e-15 55.6 0.0 6.5e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER32281.1 - 2.3e-11 43.9 0.0 2.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER32281.1 - 3.6e-10 39.9 0.0 4.1e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER32281.1 - 3.7e-06 27.1 0.1 0.00037 20.6 0.1 2.0 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_5 PF16681.5 KER32281.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.7 1 1 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 KER32281.1 - 0.0052 16.8 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 KER32281.1 - 0.0087 16.3 0.0 0.14 12.5 0.0 2.0 1 1 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 KER32281.1 - 0.044 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain BiPBP_C PF06832.12 KER32281.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Peptidase_M16_M PF16187.5 KER32284.1 - 2.7e-28 99.1 0.4 5.5e-28 98.0 0.4 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KER32284.1 - 8.9e-17 61.5 0.0 2.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KER32284.1 - 7.8e-05 22.8 0.0 0.0057 16.7 0.0 3.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain MRP-S33 PF08293.11 KER32286.1 - 4.1e-19 68.6 0.4 4.6e-19 68.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Mt_ATP-synt_B PF05405.14 KER32289.1 - 1.1e-34 119.4 0.7 1.1e-34 119.4 0.7 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mitofilin PF09731.9 KER32289.1 - 0.001 18.0 2.9 0.001 18.0 2.9 1.7 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Prefoldin_3 PF13758.6 KER32289.1 - 0.011 15.7 1.8 0.027 14.5 1.8 1.7 1 0 0 1 1 1 0 Prefoldin subunit V-ATPase_G_2 PF16999.5 KER32289.1 - 0.013 15.9 6.0 0.013 15.9 6.0 2.2 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF853 PF05872.12 KER32289.1 - 0.12 11.0 0.6 2.6 6.6 0.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) CotJB PF12652.7 KER32289.1 - 0.15 12.3 1.5 23 5.3 0.1 2.9 3 0 0 3 3 3 0 CotJB protein YrhK PF14145.6 KER32289.1 - 0.15 11.9 0.3 0.67 9.9 0.1 2.0 2 0 0 2 2 2 0 YrhK-like protein GerPC PF10737.9 KER32289.1 - 0.6 10.2 4.9 0.35 10.9 2.7 1.7 2 0 0 2 2 2 0 Spore germination protein GerPC XK-related PF09815.9 KER32290.1 - 5.6e-18 65.1 25.6 1.2e-17 64.0 25.6 1.5 1 1 0 1 1 1 1 XK-related protein DUF373 PF04123.13 KER32290.1 - 0.061 12.8 0.1 0.061 12.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) MRP-S28 PF10213.9 KER32291.1 - 2.5e-12 47.3 0.0 3.3e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Lactamase_B PF00753.27 KER32292.1 - 4.7e-08 33.3 1.8 8.5e-07 29.2 1.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KER32292.1 - 0.00014 21.5 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LCD1 PF09798.9 KER32293.1 - 0.022 13.3 0.0 0.022 13.3 0.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein SQAPI PF16845.5 KER32294.1 - 0.04 14.3 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Cystatin PF00031.21 KER32294.1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Cystatin domain fn3 PF00041.21 KER32295.1 - 4.9e-08 33.2 1.9 0.29 11.5 0.2 4.3 4 0 0 4 4 4 4 Fibronectin type III domain DUF1522 PF07482.11 KER32295.1 - 0.05 13.9 4.5 17 5.8 0.1 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1522) THDPS_M PF14789.6 KER32295.1 - 0.058 13.5 0.1 1.2e+02 2.9 0.0 3.7 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle Aida_C2 PF14186.6 KER32295.1 - 0.19 11.4 2.4 23 4.6 0.1 3.0 3 0 0 3 3 3 0 Cytoskeletal adhesion NUMOD1 PF07453.13 KER32295.1 - 0.23 11.7 5.1 20 5.6 0.2 3.4 3 0 0 3 3 3 0 NUMOD1 domain fn3 PF00041.21 KER32296.1 - 1.1e-07 32.1 0.3 7e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Asp PF00026.23 KER32297.1 - 8.4e-18 64.8 0.0 6.4e-09 35.7 0.0 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease Cas_VVA1548 PF09652.10 KER32297.1 - 0.012 15.9 0.0 6.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) zf-ANAPC11 PF12861.7 KER32297.1 - 0.039 14.0 0.0 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fer2 PF00111.27 KER32297.1 - 0.061 13.3 0.1 19 5.3 0.0 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TAXi_C PF14541.6 KER32297.1 - 0.17 11.7 0.0 0.65 9.8 0.1 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp PF00026.23 KER32298.1 - 1.1e-16 61.1 0.3 1.5e-16 60.7 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KER32298.1 - 0.0046 17.6 0.0 0.018 15.7 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease TAXi_N PF14543.6 KER32298.1 - 0.027 14.7 0.0 0.43 10.8 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.23 KER32299.1 - 8.1e-27 94.5 0.0 2e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER32299.1 - 0.053 13.3 0.0 0.59 9.9 0.1 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KER32299.1 - 0.2 12.3 0.0 2.8 8.6 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 KER32300.1 - 1.1e-34 120.3 0.0 1.3e-34 120.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER32300.1 - 0.0047 16.7 0.0 0.016 15.0 0.0 1.8 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KER32300.1 - 0.14 12.4 0.1 4 7.6 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.23 KER32301.1 - 2.1e-30 106.2 0.0 2.4e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 KER32302.1 - 1.6e-19 70.5 0.3 6e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KER32302.1 - 0.013 16.2 0.3 21 5.8 0.3 3.3 2 1 0 2 2 2 0 Aspartyl protease IL4_i_Ig PF18258.1 KER32302.1 - 0.05 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Asp PF00026.23 KER32303.1 - 4.7e-34 118.2 0.0 5.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KER32303.1 - 0.0025 18.4 0.0 0.49 11.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.23 KER32304.1 - 3e-21 76.2 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 KER32304.1 - 0.0077 16.0 0.0 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 KER32304.1 - 0.19 12.0 0.0 5.2 7.3 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Uso1_p115_head PF04869.14 KER32306.1 - 1.7e-37 129.3 0.0 3.9e-36 124.8 0.0 2.3 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 KER32306.1 - 7.8e-26 89.8 3.4 2.5e-25 88.2 3.4 2.0 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Metallophos PF00149.28 KER32306.1 - 8.2e-10 39.5 0.5 2.1e-09 38.2 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Uso1_p115_C PF04871.13 KER32306.1 - 2.4e-06 27.9 4.3 2.4e-06 27.9 4.3 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 KER32306.1 - 1.4 9.1 6.2 2.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin like CCDC53 PF10152.9 KER32306.1 - 9 6.7 6.7 2.7e+02 1.9 6.7 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex ADIP PF11559.8 KER32306.1 - 9.5 6.3 8.0 49 4.0 0.7 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding KH_1 PF00013.29 KER32307.1 - 2.3e-15 56.1 0.0 1.5e-12 47.1 0.1 3.1 2 1 0 2 2 2 2 KH domain KH_10 PF17905.1 KER32307.1 - 5.4e-07 30.0 0.2 0.039 14.4 0.1 3.6 3 0 0 3 3 3 2 GLD-3 KH domain 5 KH_4 PF13083.6 KER32307.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 KH domain AAA_6 PF12774.7 KER32308.1 - 1.3e-156 520.6 0.4 1.4e-155 517.2 0.0 2.9 3 1 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 KER32308.1 - 2.1e-105 352.3 0.0 1.1e-104 349.9 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 KER32308.1 - 1.9e-102 342.1 0.0 4.4e-102 340.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 KER32308.1 - 9.7e-93 309.3 0.7 1.7e-91 305.2 1.6 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 KER32308.1 - 4.4e-80 267.4 0.7 1.5e-73 246.2 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region DHC_N2 PF08393.13 KER32308.1 - 1.6e-55 188.9 1.0 7e-43 147.2 0.6 4.1 2 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_lid_11 PF18198.1 KER32308.1 - 1.4e-54 184.3 0.0 3.9e-54 182.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KER32308.1 - 8.1e-45 151.8 0.0 1.7e-43 147.5 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KER32308.1 - 3.2e-43 148.1 11.3 1.8e-26 93.0 3.9 2.4 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 KER32308.1 - 2.7e-24 85.7 3.0 7.1e-23 81.1 0.1 3.7 4 0 0 4 4 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 KER32308.1 - 9e-19 67.6 0.2 9e-18 64.3 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KER32308.1 - 1.1e-18 67.6 0.0 1.2e-07 31.8 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 KER32308.1 - 2e-08 34.7 0.2 0.099 13.1 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KER32308.1 - 1.3e-06 29.0 2.8 0.12 12.9 0.0 5.6 6 0 0 6 6 4 1 AAA domain AAA_16 PF13191.6 KER32308.1 - 8.4e-06 26.3 6.4 0.75 10.2 0.1 6.3 5 1 1 6 6 6 1 AAA ATPase domain AAA_22 PF13401.6 KER32308.1 - 1.7e-05 25.1 2.0 1.5 9.1 0.0 5.5 5 0 0 5 5 4 1 AAA domain T2SSE PF00437.20 KER32308.1 - 6.2e-05 22.2 0.0 0.77 8.8 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 KER32308.1 - 0.00011 21.9 0.3 0.17 11.6 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KER32308.1 - 0.00025 21.4 0.5 2.5 8.5 0.0 4.6 5 0 0 5 5 4 1 RNA helicase TsaE PF02367.17 KER32308.1 - 0.002 18.1 3.1 0.64 10.0 0.1 3.7 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KER32308.1 - 0.0026 17.7 0.1 1.7 8.5 0.0 4.0 4 0 0 4 4 4 1 RsgA GTPase AAA_33 PF13671.6 KER32308.1 - 0.0028 17.8 0.3 2.2 8.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KER32308.1 - 0.023 14.1 0.3 0.38 10.1 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KER32308.1 - 0.03 13.5 0.2 11 5.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KER32308.1 - 0.11 12.1 2.9 22 4.7 0.0 3.9 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 KER32308.1 - 0.16 12.3 0.5 16 5.8 0.0 3.5 2 0 0 2 2 2 0 AAA domain Trans_reg_C PF00486.28 KER32308.1 - 0.17 12.0 0.8 1.6 8.8 0.0 3.0 3 0 0 3 3 2 0 Transcriptional regulatory protein, C terminal DEAD PF00270.29 KER32308.1 - 0.17 11.6 0.9 1.9 8.2 0.0 3.1 3 0 0 3 3 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 KER32308.1 - 0.2 12.2 2.6 2.9 8.4 0.1 3.8 4 0 0 4 4 3 0 ABC transporter SapB_1 PF05184.15 KER32308.1 - 0.41 10.7 1.4 20 5.3 0.0 3.8 3 0 0 3 3 2 0 Saposin-like type B, region 1 Rad17 PF03215.15 KER32308.1 - 0.61 10.0 2.5 9.4 6.1 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 KER32308.1 - 4.5 6.8 7.8 15 5.1 0.3 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Yip1 PF04893.17 KER32310.1 - 9.1e-12 45.0 10.1 3.4e-11 43.2 10.1 1.8 1 1 0 1 1 1 1 Yip1 domain Inositol_P PF00459.25 KER32311.1 - 1.2e-47 162.7 0.0 1.6e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family CH PF00307.31 KER32313.1 - 4.4e-07 30.1 0.0 5.5e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Calponin homology (CH) domain DUF1997 PF09366.10 KER32314.1 - 0.087 13.0 0.0 9 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) CH PF00307.31 KER32315.1 - 5.4e-05 23.3 0.0 8.8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Calponin homology (CH) domain CDC45 PF02724.14 KER32316.1 - 0.047 12.0 7.7 0.052 11.8 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 KER32316.1 - 0.088 12.5 20.0 0.12 12.0 20.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KER32316.1 - 0.13 10.5 10.5 0.14 10.3 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 KER32316.1 - 0.22 10.6 26.7 0.27 10.3 26.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rhabdo_ncap PF00945.18 KER32316.1 - 0.38 9.6 8.0 0.52 9.1 8.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SDA1 PF05285.12 KER32316.1 - 1.2 8.5 13.3 1.7 8.0 13.3 1.3 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 KER32316.1 - 1.5 7.3 10.3 1.6 7.2 10.3 1.0 1 0 0 1 1 1 0 Utp14 protein Sporozoite_P67 PF05642.11 KER32316.1 - 1.5 6.8 7.0 1.6 6.7 7.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2796 PF10986.8 KER32316.1 - 1.6 8.6 4.7 2.3 8.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) YL1 PF05764.13 KER32316.1 - 1.7 8.7 12.0 2.1 8.4 12.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.16 KER32316.1 - 1.8 7.7 5.7 2 7.6 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KER32316.1 - 3.4 5.7 24.3 4.1 5.4 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KER32316.1 - 4.2 6.6 10.3 4.7 6.4 10.3 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 KER32316.1 - 5.1 6.8 7.9 6.4 6.5 7.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2722 PF10846.8 KER32316.1 - 5.4 5.8 10.3 6.1 5.7 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 KER32316.1 - 5.8 6.1 26.6 8.2 5.6 26.6 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 KER32316.1 - 7.4 6.1 14.2 9.9 5.7 14.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Calponin PF00402.18 KER32317.1 - 7.7e-10 38.2 1.3 1.7e-09 37.2 1.3 1.6 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 KER32317.1 - 7.8e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Engrail_1_C_sig PF10525.9 KER32318.1 - 0.02 14.1 0.2 0.098 11.9 0.2 2.3 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Fucokinase PF07959.12 KER32321.1 - 3.4e-08 32.9 3.9 4.1e-07 29.3 3.7 2.5 1 1 0 2 2 2 1 L-fucokinase Hexapep PF00132.24 KER32321.1 - 1.8e-06 27.4 4.6 0.018 14.7 1.2 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KER32321.1 - 0.0053 15.0 0.4 0.0075 14.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KER32321.1 - 0.067 13.0 7.3 0.32 10.8 0.9 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase TauD PF02668.16 KER32322.1 - 0.11 12.3 0.3 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family FH2 PF02181.23 KER32323.1 - 3.3e-75 253.5 7.4 8.2e-75 252.2 0.1 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KER32323.1 - 4.7e-22 78.6 8.4 1.1e-21 77.4 8.4 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KER32323.1 - 2.4e-21 76.1 1.5 5.3e-12 45.7 0.2 2.7 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain TolA_bind_tri PF16331.5 KER32323.1 - 0.0057 16.7 6.0 0.0057 16.7 6.0 3.0 1 1 1 2 2 2 1 TolA binding protein trimerisation CLZ PF16526.5 KER32323.1 - 0.065 13.6 0.4 0.065 13.6 0.4 5.2 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4559 PF15112.6 KER32323.1 - 0.28 10.8 8.3 0.24 11.1 6.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF4472 PF14739.6 KER32323.1 - 0.43 11.3 9.5 0.28 11.9 6.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) HalX PF08663.10 KER32323.1 - 0.44 10.9 12.7 0.24 11.7 2.6 3.0 1 1 1 2 2 2 0 HalX domain Tropomyosin_1 PF12718.7 KER32323.1 - 0.7 10.1 13.6 0.5 10.5 8.4 2.4 1 1 1 2 2 2 0 Tropomyosin like Mito_fiss_reg PF05308.11 KER32323.1 - 1.4 9.0 15.3 4.1 7.4 15.3 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator Phage_GPO PF05929.11 KER32323.1 - 1.5 8.3 12.5 4.5 6.8 7.1 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF812 PF05667.11 KER32323.1 - 2.2 7.1 12.6 4.3 6.1 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KER32323.1 - 2.8 8.4 13.2 0.44 11.0 8.8 1.9 2 0 0 2 2 1 0 Fez1 M PF02370.16 KER32323.1 - 3.1 8.7 7.3 31 5.6 0.2 3.1 2 0 0 2 2 2 0 M protein repeat ABC_tran_CTD PF16326.5 KER32323.1 - 3.6 7.9 14.8 2.3 8.5 7.2 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 KER32323.1 - 4.4 7.5 15.1 17 5.6 15.1 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Tnp_22_trimer PF17489.2 KER32323.1 - 5.6 7.0 5.5 23 5.0 0.0 3.1 3 0 0 3 3 2 0 L1 transposable element trimerization domain Golgin_A5 PF09787.9 KER32323.1 - 9.2 5.6 18.2 1.7 8.0 14.0 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 TES PF08034.11 KER32325.1 - 4.6e-09 36.4 3.0 4.6e-09 36.4 3.0 5.8 5 1 1 6 6 6 2 Trematode eggshell synthesis protein RRM_1 PF00076.22 KER32326.1 - 7.3e-34 115.4 0.2 3.4e-14 52.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER32326.1 - 2.4e-05 24.3 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KER32326.1 - 0.056 13.3 0.0 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KER32326.1 - 0.088 12.4 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 KER32326.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Limkain-b1 PF11608.8 KER32326.1 - 0.14 12.3 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 DEAD PF00270.29 KER32327.1 - 1.8e-44 151.6 0.0 5e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER32327.1 - 4.3e-29 101.1 0.0 1.8e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KER32327.1 - 0.0021 17.4 2.6 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KER32327.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 KER32327.1 - 0.11 12.6 2.7 0.2 11.8 2.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KER32327.1 - 0.67 9.7 2.5 2.6 7.8 1.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-U1 PF06220.12 KER32328.1 - 4.2e-23 80.8 8.4 5.8e-23 80.4 8.4 1.2 1 0 0 1 1 1 1 U1 zinc finger Phage_int_SAM_3 PF14659.6 KER32328.1 - 0.055 13.7 0.0 0.32 11.3 0.1 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Herpes_UL52 PF03121.15 KER32329.1 - 7.3e-08 32.2 0.1 1.8e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase CUE PF02845.16 KER32330.1 - 3.9e-07 29.6 0.0 1.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 CUE domain Apelin PF15360.6 KER32330.1 - 0.52 10.9 3.0 2.1 9.0 3.0 2.1 1 0 0 1 1 1 0 APJ endogenous ligand RT_RNaseH PF17917.1 KER32331.1 - 9.1e-08 32.3 0.1 1.5e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER32331.1 - 2.8e-06 27.3 0.4 0.00071 19.6 0.1 2.4 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase P4Ha_N PF08336.11 KER32334.1 - 2.5e-25 89.0 0.2 4.5e-25 88.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 KER32334.1 - 1.9e-13 51.1 0.0 4.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.6 KER32334.1 - 0.00019 21.4 0.2 0.00075 19.5 0.2 2.0 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KER32334.1 - 0.00027 20.8 3.4 0.0089 16.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-nanos PF05741.13 KER32334.1 - 0.0099 16.1 0.1 0.2 11.9 0.0 2.3 2 0 0 2 2 2 1 Nanos RNA binding domain TPR_4 PF07721.14 KER32334.1 - 0.091 13.4 0.3 0.39 11.5 0.3 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KER32334.1 - 0.21 11.5 2.7 0.43 10.5 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KER32334.1 - 0.84 10.6 3.6 0.9 10.5 0.1 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ig PF00047.25 KER32336.1 - 7.7e-05 22.8 0.7 0.0015 18.7 0.7 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KER32336.1 - 0.00097 19.7 0.1 0.021 15.4 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER32337.1 - 2e-06 27.9 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 KER32337.1 - 0.00074 19.0 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER32337.1 - 0.0052 16.9 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER32337.1 - 0.012 15.6 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Receptor_2B4 PF11465.8 KER32337.1 - 0.063 13.5 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Amino_oxidase PF01593.24 KER32338.1 - 3.5e-26 92.5 0.0 6.3e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KER32338.1 - 9.1e-11 41.8 0.1 1.9e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KER32338.1 - 9e-09 35.4 0.0 4.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase MCRA PF06100.11 KER32338.1 - 0.006 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 MCRA family ApbA PF02558.16 KER32338.1 - 0.04 13.6 0.0 9.4 5.9 0.0 2.4 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KER32338.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KER32338.1 - 0.17 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog_N PF02812.18 KER32340.1 - 2e-54 183.0 0.0 3.3e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KER32340.1 - 5.3e-53 180.2 0.0 1.2e-50 172.5 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KER32340.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.20 KER32341.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF4785 PF16024.5 KER32341.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) DNA_ligase_A_M PF01068.21 KER32342.1 - 2.7e-58 197.0 0.1 5.2e-57 192.8 0.1 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KER32342.1 - 2.3e-25 89.1 0.0 7.5e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 KER32342.1 - 3e-24 86.3 0.1 6.6e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_OB_2 PF14743.6 KER32342.1 - 0.023 14.7 0.6 8.6 6.5 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain GHL13 PF14883.6 KER32342.1 - 0.081 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 STIL_N PF15253.6 KER32343.1 - 9e-06 24.9 0.0 2.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus STIL_N PF15253.6 KER32344.1 - 0.0014 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus 7tm_1 PF00001.21 KER32345.1 - 2.9e-05 23.5 7.7 9.9e-05 21.8 7.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_5 PF13893.6 KER32347.1 - 2.9e-37 127.0 1.9 3.2e-23 81.7 0.0 4.3 3 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KER32347.1 - 5.3e-22 77.4 0.0 0.00035 20.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KER32347.1 - 3.9e-11 42.7 0.2 0.00096 19.0 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_8 PF11835.8 KER32347.1 - 9.7e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain cobW PF02492.19 KER32349.1 - 1.3e-50 171.4 0.7 8.1e-50 168.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KER32349.1 - 5.5e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KER32349.1 - 0.00028 20.8 0.4 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 KER32349.1 - 0.024 13.7 0.6 0.58 9.1 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KER32349.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KER32349.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KER32349.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KER32349.1 - 0.12 12.9 0.1 0.85 10.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain DHO_dh PF01180.21 KER32350.1 - 2.9e-86 289.3 0.0 3.8e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KER32350.1 - 0.00098 18.2 0.0 0.036 13.1 0.1 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KER32350.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase SEF14_adhesin PF06443.11 KER32350.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 SEF14-like adhesin CARD PF00619.21 KER32351.1 - 0.025 14.6 0.4 0.032 14.2 0.3 1.4 1 1 0 1 1 1 0 Caspase recruitment domain 7tm_1 PF00001.21 KER32353.1 - 1.4e-11 44.2 12.0 2.9e-11 43.2 12.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EzrA PF06160.12 KER32353.1 - 0.0073 14.5 0.5 2.1 6.4 0.1 2.2 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA RRM_1 PF00076.22 KER32353.1 - 0.076 12.9 0.6 16 5.4 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5316 PF17247.2 KER32353.1 - 1.4 8.9 4.6 1.1 9.3 0.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5316) 7tm_1 PF00001.21 KER32354.1 - 3.4e-17 62.7 3.9 3.5e-17 62.6 2.7 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER32354.1 - 0.0055 16.1 10.5 0.051 12.9 10.5 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KER32354.1 - 0.027 13.5 0.2 0.027 13.5 0.2 1.9 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region 7TM_GPCR_Srw PF10324.9 KER32355.1 - 0.00035 20.0 20.8 0.0035 16.7 20.7 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER32355.1 - 0.00099 18.5 17.5 0.00099 18.5 17.5 2.1 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) REPA_OB_2 PF16900.5 KER32357.1 - 0.0028 17.6 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 Replication protein A OB domain TSR PF18487.1 KER32357.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 repeat PWWP PF00855.17 KER32358.1 - 4.9e-08 33.3 0.1 1.1e-07 32.2 0.1 1.6 1 0 0 1 1 1 1 PWWP domain VKG_Carbox PF05090.14 KER32359.1 - 0.061 12.1 0.1 0.073 11.9 0.1 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Ank_4 PF13637.6 KER32360.1 - 1.8e-20 73.0 11.7 1.6e-07 31.7 0.4 2.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER32360.1 - 6.5e-13 49.1 4.7 1.3e-09 38.5 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KER32360.1 - 1.6e-10 40.3 5.3 0.00013 22.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KER32360.1 - 3e-07 30.6 7.7 6e-05 23.3 0.1 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KER32360.1 - 7.8e-07 29.3 4.5 0.00021 21.5 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Gln-synt_C PF00120.24 KER32362.1 - 1.4e-71 241.3 0.0 1.9e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain RRM_1 PF00076.22 KER32363.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IF4E PF01652.18 KER32364.1 - 4.4e-41 140.3 0.1 5.3e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4061 PF13270.6 KER32365.1 - 3e-12 46.7 0.1 4.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF2760 PF10816.8 KER32365.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) MLTR_LBD PF17765.1 KER32365.1 - 0.025 14.7 0.0 0.028 14.6 0.0 1.0 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Uds1 PF15456.6 KER32365.1 - 0.034 14.3 0.4 0.043 14.0 0.4 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Globin PF00042.22 KER32366.1 - 0.00015 22.3 0.0 0.00029 21.4 0.0 1.5 1 0 0 1 1 1 1 Globin UME PF08064.13 KER32366.1 - 0.046 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 UME (NUC010) domain TPR_8 PF13181.6 KER32367.1 - 3e-13 48.9 1.6 0.094 13.0 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KER32367.1 - 5.3e-13 48.6 6.7 0.16 12.9 0.1 8.1 5 3 3 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER32367.1 - 5.9e-12 45.9 3.7 0.079 13.5 0.0 7.4 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER32367.1 - 1.1e-10 41.1 3.8 0.07 13.5 0.0 8.0 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER32367.1 - 8.5e-10 38.0 7.1 0.64 10.3 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KER32367.1 - 4.9e-09 35.8 1.1 0.003 16.8 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER32367.1 - 7.3e-09 36.1 4.3 0.043 14.5 0.1 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER32367.1 - 1.5e-07 31.0 8.5 1.2 9.1 0.2 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KER32367.1 - 2e-06 28.0 0.4 1 9.6 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KER32367.1 - 4.3e-06 26.9 0.7 2.9 8.8 0.4 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER32367.1 - 3.7e-05 23.4 8.9 19 5.5 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KER32367.1 - 0.00013 22.3 7.8 28 5.6 0.1 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER32367.1 - 0.0003 21.0 16.2 2.6 8.4 1.8 6.8 5 3 2 7 7 6 4 Tetratricopeptide repeat TPR_20 PF14561.6 KER32367.1 - 0.02 15.2 3.5 6.5 7.2 0.1 4.9 5 2 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 KER32367.1 - 0.021 13.8 0.1 1.4 7.8 0.0 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KER32367.1 - 0.023 14.5 12.7 7.7 6.5 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KER32367.1 - 0.025 14.7 0.5 0.93 9.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1373 PF07117.11 KER32367.1 - 0.054 13.5 1.1 0.12 12.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Vac14_Fab1_bd PF12755.7 KER32367.1 - 0.088 13.4 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region AAA_11 PF13086.6 KER32367.1 - 4.1 7.1 7.6 0.52 10.1 2.6 1.8 2 0 0 2 2 2 0 AAA domain E1_dh PF00676.20 KER32368.1 - 1.3e-101 339.5 0.0 2.1e-73 246.9 0.0 2.1 2 0 0 2 2 2 2 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KER32368.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF1194 PF06707.11 KER32368.1 - 0.04 13.1 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) TPP_enzyme_C PF02775.21 KER32368.1 - 0.13 12.0 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_C78 PF07910.13 KER32369.1 - 2.3e-43 148.2 0.0 3.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Vps8 PF12816.7 KER32370.1 - 4.4e-23 81.8 0.1 3.8e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_11 PF17123.5 KER32370.1 - 0.01 15.5 1.1 0.048 13.4 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger Clathrin PF00637.20 KER32370.1 - 0.024 14.5 0.5 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS zf-rbx1 PF12678.7 KER32370.1 - 0.031 14.6 9.8 0.091 13.1 9.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 KER32370.1 - 0.046 13.6 4.4 0.14 12.1 4.4 1.8 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 KER32370.1 - 0.065 14.1 0.1 0.51 11.3 0.1 2.7 1 0 0 1 1 1 0 WD domain, G-beta repeat TPR_7 PF13176.6 KER32370.1 - 0.13 12.4 0.1 0.49 10.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KER32370.1 - 0.13 12.6 0.0 3 8.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 KER32370.1 - 0.27 11.6 10.3 1.2 9.5 10.3 2.3 1 0 0 1 1 1 0 Ring finger domain Methyltransf_16 PF10294.9 KER32372.1 - 4.4e-13 49.3 0.0 6.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KER32372.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER32372.1 - 0.0011 19.6 0.0 0.0034 18.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KER32372.1 - 0.0071 15.9 0.0 0.034 13.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KER32372.1 - 0.021 14.6 0.0 0.075 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KER32372.1 - 0.2 11.0 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4218 PF13960.6 KER32373.1 - 0.00043 19.9 0.1 0.00077 19.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Nop PF01798.18 KER32374.1 - 8.6e-32 110.4 1.0 1.6e-15 57.2 2.9 3.0 2 1 0 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KER32374.1 - 4e-10 39.9 0.4 8.6e-10 38.9 0.4 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF4710 PF15828.5 KER32374.1 - 0.27 11.4 1.5 0.56 10.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) COX4 PF02936.14 KER32375.1 - 2.5e-25 89.1 0.0 3.6e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV BolA PF01722.18 KER32375.1 - 5.6e-06 26.5 0.2 1.1e-05 25.7 0.2 1.4 1 0 0 1 1 1 1 BolA-like protein DUF4748 PF15932.5 KER32375.1 - 1.5 8.6 3.2 2.8 7.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Sin_N PF04801.13 KER32376.1 - 7.5e-42 144.0 0.0 6.4e-41 141.0 0.0 2.2 2 0 0 2 2 2 1 Sin-like protein conserved region TFIIF_beta PF02270.15 KER32376.1 - 7e-05 22.9 0.3 0.011 15.8 0.0 3.1 3 0 0 3 3 3 1 TFIIF, beta subunit HTH domain DUF1780 PF08682.10 KER32377.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) Mito_carr PF00153.27 KER32379.1 - 1.4e-62 207.6 0.4 3.3e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 7tm_1 PF00001.21 KER32381.1 - 3.5e-15 56.1 14.8 5.7e-15 55.3 13.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER32381.1 - 2e-07 30.6 9.2 0.0011 18.3 0.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 KER32381.1 - 0.00021 20.8 1.7 0.00021 20.8 1.7 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Serpentine_r_xa PF03383.15 KER32381.1 - 0.0044 17.0 2.1 0.012 15.6 2.1 1.7 1 0 0 1 1 1 1 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.9 KER32381.1 - 0.0085 15.7 6.8 0.0085 15.7 6.8 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx GMC_oxred_N PF00732.19 KER32382.1 - 2.3e-82 276.7 0.2 1.4e-80 270.9 0.0 2.4 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KER32382.1 - 2.1e-33 115.9 0.0 3.5e-31 108.6 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase HAD_2 PF13419.6 KER32382.1 - 8.2e-22 78.1 0.0 1.5e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KER32382.1 - 4.7e-18 66.2 0.0 1.4e-07 32.0 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KER32382.1 - 1.1e-06 28.6 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KER32382.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-RING_UBOX PF13445.6 KER32383.1 - 3.7e-08 33.3 32.6 4.3e-06 26.6 5.7 4.0 3 0 0 3 3 3 3 RING-type zinc-finger IBR PF01485.21 KER32383.1 - 5.3e-08 33.0 45.4 1.7e-06 28.2 6.1 5.5 6 1 0 6 6 6 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KER32383.1 - 0.00011 22.5 41.4 0.00044 20.5 3.7 4.5 4 0 0 4 4 4 3 Ring finger domain zf-C3HC4 PF00097.25 KER32383.1 - 0.0002 21.1 39.2 0.00071 19.4 2.8 4.4 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER32383.1 - 0.013 15.4 3.6 0.013 15.4 3.6 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) LRR19-TM PF15176.6 KER32383.1 - 0.19 11.7 5.8 0.28 11.2 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain zf-RING_5 PF14634.6 KER32383.1 - 0.39 10.7 40.7 0.1 12.5 4.5 4.5 4 0 0 4 4 4 0 zinc-RING finger domain Ax_dynein_light PF10211.9 KER32385.1 - 2.5e-63 213.4 4.3 3.1e-63 213.1 4.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain BST2 PF16716.5 KER32385.1 - 0.032 14.8 1.2 0.032 14.8 1.2 2.3 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 ApoO PF09769.9 KER32385.1 - 0.11 12.5 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Apolipoprotein O ADIP PF11559.8 KER32385.1 - 3.1 7.9 13.5 0.44 10.6 9.5 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Homeodomain PF00046.29 KER32386.1 - 2.7e-21 75.2 7.8 4.8e-21 74.4 7.8 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER32386.1 - 0.019 14.9 0.4 0.051 13.5 0.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain 7TMR-HDED PF07697.11 KER32387.1 - 0.011 15.9 5.2 0.02 15.0 4.8 1.5 1 1 0 1 1 1 0 7TM-HD extracellular MA3 PF02847.17 KER32387.1 - 0.015 15.3 1.2 0.028 14.4 0.2 2.0 2 0 0 2 2 2 0 MA3 domain Na_K-ATPase PF00287.18 KER32388.1 - 2.1e-29 102.6 0.9 3.2e-29 102.0 0.9 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Ion_trans PF00520.31 KER32392.1 - 9.9e-06 25.0 3.0 1.3e-05 24.6 3.0 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KER32392.1 - 0.08 11.6 2.8 0.12 11.0 2.8 1.2 1 0 0 1 1 1 0 Polycystin cation channel Nic96 PF04097.14 KER32393.1 - 4.3e-112 375.6 0.1 2.2e-98 330.3 0.4 2.1 2 0 0 2 2 2 2 Nup93/Nic96 Tcf25 PF04910.14 KER32394.1 - 5.2e-50 170.5 0.0 6.3e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Retrotrans_gag PF03732.17 KER32396.1 - 8.4e-05 22.8 0.1 0.00081 19.6 0.0 2.5 1 1 1 2 2 2 1 Retrotransposon gag protein Pkinase PF00069.25 KER32397.1 - 5.5e-61 206.2 0.0 7.6e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32397.1 - 7.5e-42 143.4 0.0 1.2e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KER32397.1 - 3.1e-08 33.7 0.0 7.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 KER32397.1 - 0.0015 17.9 0.0 0.004 16.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KER32397.1 - 0.005 16.5 0.1 0.016 14.8 0.1 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 KER32397.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER32397.1 - 0.015 14.3 0.2 0.04 12.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KER32397.1 - 0.036 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5520 PF17658.1 KER32397.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5520) PHO4 PF01384.20 KER32398.1 - 2.1e-130 434.7 5.4 2.6e-130 434.4 5.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Peptidase_C14 PF00656.22 KER32399.1 - 6.4e-42 144.2 0.0 7.6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain iPGM_N PF06415.13 KER32399.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) cNMP_binding PF00027.29 KER32400.1 - 5.3e-21 74.5 0.0 1.3e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 KER32400.1 - 0.036 14.0 1.1 0.053 13.5 0.4 1.6 2 0 0 2 2 2 0 Ion channel Ion_trans PF00520.31 KER32401.1 - 1.5e-07 30.9 4.5 1.7e-07 30.8 4.5 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.10 KER32402.1 - 1.2e-25 88.8 0.3 3.2e-25 87.4 0.3 1.8 1 0 0 1 1 1 1 Ion transport protein N-terminal FRG1 PF06229.12 KER32403.1 - 4.5e-85 284.2 0.0 1.1e-60 204.6 0.0 2.8 2 1 1 3 3 3 2 FRG1-like domain DUF1754 PF08555.10 KER32403.1 - 0.00024 21.8 4.9 0.0006 20.6 4.9 1.6 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF3945 PF13101.6 KER32403.1 - 0.051 13.3 0.1 29 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3945) CENP-C_C PF11699.8 KER32403.1 - 0.11 12.8 0.5 0.21 11.8 0.5 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like PDEase_I PF00233.19 KER32404.1 - 1.5e-85 286.7 0.2 2.8e-85 285.8 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CENP-B_dimeris PF09026.10 KER32405.1 - 0.001 19.4 13.3 0.0019 18.6 13.3 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 KER32405.1 - 0.0024 17.9 2.0 0.0038 17.3 2.0 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KER32405.1 - 0.005 16.6 10.0 0.0066 16.2 10.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 KER32405.1 - 0.028 14.1 0.5 0.051 13.2 0.5 1.5 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 KER32405.1 - 0.078 12.4 3.8 0.11 11.9 3.8 1.2 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 KER32405.1 - 0.083 13.3 13.0 0.21 12.0 13.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 KER32405.1 - 0.13 11.4 18.3 0.21 10.7 18.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 KER32405.1 - 0.27 10.8 5.0 0.41 10.2 5.0 1.3 1 0 0 1 1 1 0 PPP4R2 GCIP PF13324.6 KER32405.1 - 0.35 10.4 4.4 0.53 9.8 4.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 KER32405.1 - 0.81 7.9 7.9 1.1 7.4 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 KER32405.1 - 0.86 7.6 2.3 1 7.3 2.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KER32405.1 - 0.96 7.5 15.5 1.6 6.7 15.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 KER32405.1 - 1.1 8.5 6.1 1.6 8.0 6.1 1.2 1 0 0 1 1 1 0 BUD22 DUF3245 PF11595.8 KER32405.1 - 1.2 9.6 10.6 2.9e+02 1.8 10.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) DUF3295 PF11702.8 KER32405.1 - 1.7 7.9 5.7 2.3 7.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Sigma70_ner PF04546.13 KER32405.1 - 2.1 8.2 8.3 4.1 7.2 8.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Utp14 PF04615.13 KER32405.1 - 2.6 6.5 8.2 3.5 6.1 8.2 1.1 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 KER32405.1 - 2.7 7.3 20.8 4.3 6.6 20.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KER32405.1 - 3.9 5.6 9.4 5.3 5.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.6 KER32405.1 - 6.9 7.0 17.7 16 5.8 17.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) YL1 PF05764.13 KER32405.1 - 8.4 6.4 11.6 14 5.7 11.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.32 KER32407.1 - 2.1e-37 126.4 6.8 1.1e-07 32.3 0.4 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER32407.1 - 1.9e-18 66.5 0.0 4.5e-05 23.7 0.0 5.4 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KER32407.1 - 2.4e-12 46.3 0.2 4.5e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 KER32407.1 - 2.6e-10 39.8 0.0 0.0068 15.4 0.0 3.7 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KER32407.1 - 2.8e-06 26.3 0.0 0.59 8.7 0.0 4.4 1 1 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KER32407.1 - 0.03 13.7 0.0 0.35 10.2 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain Cucumo_coat PF00760.18 KER32409.1 - 0.022 14.4 0.0 0.026 14.2 0.0 1.0 1 0 0 1 1 1 0 Cucumovirus coat protein Flavodoxin_1 PF00258.25 KER32413.1 - 4e-17 62.8 0.0 2.3e-15 57.0 0.0 2.4 1 1 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KER32413.1 - 6.9e-12 45.4 0.0 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 KER32413.1 - 1.1e-11 45.4 0.0 2.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 KER32414.1 - 3e-18 66.4 0.0 3.4e-16 59.8 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin Tetraspanin PF00335.20 KER32415.1 - 4.3e-24 85.5 12.6 5.8e-17 62.2 9.7 2.0 1 1 1 2 2 2 2 Tetraspanin family DUF2569 PF10754.9 KER32415.1 - 0.032 14.7 2.5 0.041 14.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Pox_A14 PF05767.12 KER32415.1 - 0.036 14.2 4.3 0.054 13.7 4.3 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Dynein_light PF01221.18 KER32418.1 - 7.1e-32 109.6 5.0 6.3e-24 84.1 0.2 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 Dynein_light PF01221.18 KER32420.1 - 9.8e-38 128.4 0.5 1.1e-37 128.2 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 N_NLPC_P60 PF12912.7 KER32420.1 - 0.11 12.9 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Dynein_light PF01221.18 KER32421.1 - 8.3e-49 163.8 8.0 9.7e-31 105.9 0.5 2.4 2 1 1 3 3 3 2 Dynein light chain type 1 DUF3194 PF11419.8 KER32421.1 - 0.00043 20.6 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3194) HTH_33 PF13592.6 KER32421.1 - 0.0024 17.5 0.3 3.5 7.3 0.0 2.7 2 2 0 2 2 2 2 Winged helix-turn helix GST_C PF00043.25 KER32421.1 - 0.0025 18.0 0.6 1.4 9.2 0.1 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain EPF PF17181.4 KER32421.1 - 0.0028 17.6 0.9 2.5 8.1 0.1 2.3 2 0 0 2 2 2 2 Epidermal patterning factor proteins RNase_J_C PF17770.1 KER32421.1 - 0.0046 18.0 1.1 5.2 8.2 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease J C-terminal domain Imm6 PF14434.6 KER32421.1 - 0.0055 16.6 1.7 2.8 7.9 0.2 2.5 2 1 0 2 2 2 2 Immunity protein Imm6 Ground-like PF04155.18 KER32421.1 - 0.0058 17.3 4.2 2.7 8.7 1.6 3.4 1 1 1 2 2 2 1 Ground-like domain SMBP PF16785.5 KER32421.1 - 0.0067 16.6 0.2 1.6 9.0 0.0 2.1 2 0 0 2 2 2 1 Small metal-binding protein M20_dimer PF07687.14 KER32421.1 - 0.0076 16.2 0.0 3.9 7.4 0.0 2.1 1 1 1 2 2 2 2 Peptidase dimerisation domain RIO1 PF01163.22 KER32421.1 - 0.019 14.6 0.3 0.032 13.8 0.1 1.5 1 1 1 2 2 2 0 RIO1 family TSP_NTD PF17804.1 KER32421.1 - 0.021 15.1 0.1 6 7.1 0.0 2.1 2 0 0 2 2 2 0 Tail specific protease N-terminal domain DXPR_C PF13288.6 KER32421.1 - 0.027 14.7 2.5 5.3 7.3 0.2 2.4 1 1 0 2 2 2 0 DXP reductoisomerase C-terminal domain CLAMP PF14769.6 KER32421.1 - 0.031 14.7 0.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 MT0933_antitox PF14013.6 KER32421.1 - 0.035 14.4 1.9 7.3 7.0 0.1 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein Reticulon PF02453.17 KER32421.1 - 0.037 14.0 0.0 6.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Reticulon DUF1904 PF08921.11 KER32421.1 - 0.044 14.1 0.6 9.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) DUF2087 PF09860.9 KER32421.1 - 0.054 13.7 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) FadA PF09403.10 KER32421.1 - 0.071 13.6 3.4 6.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Adhesion protein FadA DUF4423 PF14394.6 KER32421.1 - 0.074 12.8 0.1 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DASH_Duo1 PF08651.10 KER32421.1 - 0.087 12.6 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 Troponin PF00992.20 KER32421.1 - 0.11 12.8 0.7 7.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Troponin TssC PF17541.2 KER32421.1 - 0.16 10.8 1.6 4.7 5.9 0.1 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssC, VipB LZ3wCH PF18517.1 KER32421.1 - 0.97 9.6 4.8 16 5.7 0.4 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain YtxH PF12732.7 KER32421.1 - 2.5 8.7 5.8 19 5.9 0.3 2.2 2 0 0 2 2 2 0 YtxH-like protein Dynein_light PF01221.18 KER32422.1 - 3.4e-19 68.9 0.3 5.5e-19 68.3 0.3 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 KER32423.1 - 5e-36 122.9 0.2 5.5e-36 122.8 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 KER32424.1 - 2.1e-25 88.8 0.0 2.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KER32424.1 - 0.055 12.9 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin NIF3 PF01784.18 KER32425.1 - 1.4e-65 221.4 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Gemin6 PF06372.12 KER32426.1 - 0.057 13.0 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Gemin6 protein VPS53_C PF16854.5 KER32426.1 - 0.16 11.8 3.0 0.34 10.8 0.6 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus Beta_protein PF14350.6 KER32426.1 - 0.19 11.1 1.2 0.55 9.6 0.4 2.2 2 1 0 2 2 2 0 Beta protein Lectin_C PF00059.21 KER32429.1 - 0.0038 17.9 0.0 0.0038 17.9 0.0 2.6 3 0 0 3 3 3 1 Lectin C-type domain Asp-B-Hydro_N PF05279.11 KER32429.1 - 1.5 8.9 16.2 2.3 8.2 16.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SWI-SNF_Ssr4 PF08549.10 KER32429.1 - 4.7 5.7 22.4 1.2 7.6 19.3 1.5 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) SAPS PF04499.15 KER32429.1 - 5.9 5.6 12.5 10 4.8 12.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glycos_transf_4 PF00953.21 KER32430.1 - 9e-22 77.8 4.9 9e-22 77.8 4.9 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 RVT_1 PF00078.27 KER32430.1 - 0.0056 16.2 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Claudin_2 PF13903.6 KER32432.1 - 1.5e-07 31.4 2.9 2.3e-07 30.7 2.9 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction RNase_T PF00929.24 KER32433.1 - 1.8e-22 80.7 0.0 2.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Nucleoside_tran PF01733.18 KER32436.1 - 3.4e-32 112.1 11.2 8.6e-28 97.6 7.9 3.2 2 1 0 2 2 2 2 Nucleoside transporter AGP PF06376.12 KER32436.1 - 0.8 9.6 2.8 1.6 8.6 2.8 1.5 1 0 0 1 1 1 0 Arabinogalactan peptide DUF5082 PF16888.5 KER32437.1 - 0.14 12.4 0.7 0.46 10.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SlyX PF04102.12 KER32437.1 - 0.69 10.6 4.2 0.93 10.2 1.1 2.6 2 0 0 2 2 2 0 SlyX Med9 PF07544.13 KER32437.1 - 1.1 9.4 6.2 3.7 7.7 3.8 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2165 PF09933.9 KER32438.1 - 0.076 13.0 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Toxin_TOLIP PF00087.21 KER32439.1 - 0.00014 22.0 15.4 0.00033 20.9 15.4 1.6 1 1 0 1 1 1 1 Snake toxin and toxin-like protein Activin_recp PF01064.23 KER32439.1 - 0.32 12.1 12.3 0.57 11.3 12.3 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain G-alpha PF00503.20 KER32440.1 - 8.7e-53 179.7 0.8 4.3e-49 167.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KER32440.1 - 0.073 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 KER32440.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KER32440.1 - 0.12 12.1 0.2 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain W2 PF02020.18 KER32441.1 - 2.9e-14 53.0 0.8 6.2e-14 51.9 0.8 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KER32441.1 - 7.7e-05 22.4 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KER32441.1 - 0.0011 18.6 1.3 0.024 14.4 0.4 3.3 2 1 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KER32441.1 - 0.0035 17.7 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KER32441.1 - 0.095 10.8 0.1 0.68 8.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Fer2_4 PF13510.6 KER32443.1 - 1.1e-17 63.9 0.3 2.2e-17 62.8 0.3 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KER32443.1 - 1.5e-16 59.6 0.2 1.5e-16 59.6 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KER32443.1 - 2.9e-07 30.4 1.4 2.9e-07 30.4 1.4 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KER32443.1 - 0.27 11.1 1.4 5.3 7.0 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain HMG_box PF00505.19 KER32444.1 - 1.2e-12 48.0 3.5 2.5e-12 47.0 3.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF4819 PF16090.5 KER32444.1 - 2.3e-06 27.6 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4819) HMG_box_2 PF09011.10 KER32444.1 - 7.6e-06 26.4 1.4 1.7e-05 25.3 1.4 1.6 1 0 0 1 1 1 1 HMG-box domain RVT_1 PF00078.27 KER32445.1 - 1.8e-38 132.2 0.0 2.9e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IFT46_B_C PF12317.8 KER32448.1 - 1.1e-76 257.3 3.4 2.4e-76 256.2 3.4 1.5 1 1 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal CENP-B_dimeris PF09026.10 KER32448.1 - 0.017 15.5 7.3 0.033 14.6 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KER32448.1 - 0.022 14.5 5.7 0.036 13.8 5.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tim54 PF11711.8 KER32448.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4611 PF15387.6 KER32448.1 - 0.6 10.4 5.4 1.5 9.1 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KER32448.1 - 1.3 8.3 7.4 2 7.6 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 KER32448.1 - 1.5 8.5 4.8 3.3 7.5 4.7 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein RRN3 PF05327.11 KER32448.1 - 1.8 7.0 3.7 1.2 7.6 2.0 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Beta-lactamase PF00144.24 KER32449.1 - 1.1e-43 149.7 0.0 3.3e-43 148.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KER32449.1 - 0.0082 15.6 0.0 0.099 12.1 0.0 2.1 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase DUF2576 PF10845.8 KER32449.1 - 0.076 12.6 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Tetraspanin PF00335.20 KER32451.1 - 1.8e-13 50.7 6.3 3e-13 50.0 6.3 1.4 1 1 0 1 1 1 1 Tetraspanin family zf-A20 PF01754.16 KER32452.1 - 2.9e-12 46.3 6.2 1e-11 44.5 6.2 2.0 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 KER32452.1 - 6.2e-09 35.9 6.4 6.2e-09 35.9 6.4 2.6 2 1 0 2 2 2 1 AN1-like Zinc finger Spem1 PF15670.5 KER32452.1 - 0.081 12.5 0.6 0.11 12.1 0.6 1.4 1 1 0 1 1 1 0 Spermatid maturation protein 1 Flocculin PF00624.18 KER32452.1 - 0.49 10.7 2.8 0.71 10.2 2.8 1.2 1 0 0 1 1 1 0 Flocculin repeat Btz PF09405.10 KER32453.1 - 4.6e-06 26.9 1.8 4.6e-06 26.9 1.8 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 KER32457.1 - 5.9e-13 48.8 0.0 8.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32457.1 - 0.00059 19.2 0.1 0.00078 18.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER32457.1 - 0.017 14.5 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3343 PF11823.8 KER32457.1 - 0.094 12.2 1.0 1 8.9 0.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3343) Pkinase PF00069.25 KER32458.1 - 9.3e-05 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KER32459.1 - 3.6e-08 33.1 0.0 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Lipid_DES PF08557.10 KER32459.1 - 0.58 9.7 4.1 14 5.3 0.3 2.4 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) UCH PF00443.29 KER32464.1 - 2.2e-54 184.7 0.6 3.5e-54 184.0 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER32464.1 - 2.7e-13 50.2 2.7 1.6e-11 44.4 2.7 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RIC3 PF15361.6 KER32466.1 - 3.4e-19 69.7 0.0 1.1e-18 68.0 0.0 1.8 1 1 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 Sec66 PF09802.9 KER32466.1 - 0.00087 18.9 0.0 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 DAGK_acc PF00609.19 KER32468.1 - 5.5e-43 147.1 0.0 1.1e-42 146.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KER32468.1 - 3e-19 68.9 0.0 9.5e-19 67.3 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 KER32468.1 - 3.4e-15 55.7 28.4 1.3e-11 44.2 12.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 KER32468.1 - 3.3e-10 40.5 0.0 4.9e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain Glyco_transf_8 PF01501.20 KER32470.1 - 3.2e-07 30.2 0.1 5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 KER32472.1 - 2.6e-05 23.9 2.1 0.00015 21.4 0.1 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 8 Dynein_light PF01221.18 KER32475.1 - 4.1e-44 148.8 2.2 4.5e-44 148.7 2.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.29 KER32475.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ectatomin PF06457.11 KER32475.1 - 0.17 11.8 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Ectatomin Dynein_light PF01221.18 KER32476.1 - 7.9e-55 183.2 0.5 1.4e-34 118.2 0.1 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 DUF3109 PF11307.8 KER32476.1 - 0.00093 19.0 0.0 1.3 8.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3109) Nop PF01798.18 KER32476.1 - 0.0011 18.5 0.0 0.39 10.1 0.0 2.0 1 1 1 2 2 2 2 snoRNA binding domain, fibrillarin Tho1_MOS11_C PF18592.1 KER32476.1 - 0.017 15.0 0.1 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain HEPN_Swt1 PF18731.1 KER32476.1 - 0.026 14.8 0.0 9.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Swt1-like HEPN Imm6 PF14434.6 KER32476.1 - 0.031 14.2 0.0 21 5.1 0.0 3.4 1 1 1 2 2 2 0 Immunity protein Imm6 PBP-Tp47_a PF14889.6 KER32476.1 - 0.031 13.9 0.0 7.2 6.2 0.0 2.2 1 1 0 2 2 2 0 Penicillin-binding protein Tp47 domain a p450 PF00067.22 KER32476.1 - 0.042 12.6 0.1 0.86 8.3 0.0 2.0 1 1 1 2 2 2 0 Cytochrome P450 Tox-REase-9 PF15650.6 KER32476.1 - 0.14 12.5 0.1 13 6.1 0.0 2.5 1 1 0 2 2 2 0 Restriction endonuclease fold toxin 9 Zip PF02535.22 KER32477.1 - 1.6e-35 122.9 4.7 4.4e-20 72.2 0.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF21 PF01595.20 KER32477.1 - 0.1 12.3 3.7 0.24 11.1 3.2 1.9 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Ig_3 PF13927.6 KER32478.1 - 4.5e-27 94.5 0.3 4.7e-14 52.8 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KER32478.1 - 1.8e-24 85.6 0.0 9.6e-13 48.0 0.0 3.7 3 1 1 4 4 4 3 Immunoglobulin I-set domain V-set PF07686.17 KER32478.1 - 3.4e-22 78.7 1.5 1.7e-09 37.8 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 KER32478.1 - 7.8e-18 64.4 0.6 5.1e-05 23.4 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KER32478.1 - 6.2e-17 61.7 0.4 3.6e-10 40.0 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 KER32478.1 - 1.5e-08 34.3 1.8 1.1e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 KER32478.1 - 1.6e-06 27.6 0.2 1.1 8.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 KER32478.1 - 0.044 13.9 1.9 12 6.1 0.0 3.7 3 1 0 3 3 3 0 Izumo-like Immunoglobulin domain LIM PF00412.22 KER32479.1 - 4.1e-19 68.6 44.6 6.9e-09 35.8 10.3 3.6 3 0 0 3 3 3 3 LIM domain Homeodomain PF00046.29 KER32479.1 - 3.5e-16 58.8 1.0 8.5e-16 57.6 1.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER32479.1 - 0.15 12.0 0.3 0.42 10.6 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain PSCyt3 PF07627.11 KER32479.1 - 2.3 8.5 6.8 0.54 10.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) zf-His_Me_endon PF05551.11 KER32480.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease ASC PF00858.24 KER32481.1 - 1.5e-58 198.8 4.1 2.8e-58 198.0 4.1 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel DUF3695 PF12494.8 KER32483.1 - 5.3e-16 58.3 0.1 8.4e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) OATP PF03137.20 KER32484.1 - 9.2e-134 446.7 13.2 1.3e-99 334.0 0.4 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KER32484.1 - 1.7e-15 56.8 23.2 4.3e-15 55.5 16.5 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.15 KER32484.1 - 0.061 13.5 9.6 0.14 12.3 8.5 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain YlaC PF10777.9 KER32484.1 - 0.13 12.1 0.1 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC Dynein_light PF01221.18 KER32485.1 - 2.4e-29 101.5 3.1 6e-22 77.8 0.2 2.1 2 0 0 2 2 2 2 Dynein light chain type 1 Swm2 PF17083.5 KER32485.1 - 0.054 13.5 0.1 0.075 13.0 0.1 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Dynein_light PF01221.18 KER32486.1 - 1.3e-27 95.9 0.6 1.4e-27 95.8 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 KER32486.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Cytidylate_kin PF02224.18 KER32486.1 - 0.04 13.7 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Ecotin PF03974.13 KER32486.1 - 0.083 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Ecotin Dynein_light PF01221.18 KER32488.1 - 4.4e-27 94.2 0.6 4.7e-27 94.1 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 KER32488.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain Dynein_light PF01221.18 KER32489.1 - 4.9e-32 110.1 0.1 5.3e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 KER32490.1 - 7e-38 128.8 3.4 7.7e-38 128.7 3.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 KER32491.1 - 5.2e-38 129.2 4.4 5.7e-38 129.1 4.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 I-set PF07679.16 KER32492.1 - 7.1e-25 86.9 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 KER32492.1 - 6.6e-17 61.9 0.0 2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KER32492.1 - 4.5e-12 46.0 0.0 5.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 KER32492.1 - 8.8e-10 38.8 0.0 0.00073 19.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER32492.1 - 8.6e-06 25.9 0.0 0.023 14.9 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER32492.1 - 0.0072 16.4 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain TPR_19 PF14559.6 KER32493.1 - 1.3e-40 137.7 52.0 0.00014 22.3 0.2 15.3 12 4 4 17 17 16 13 Tetratricopeptide repeat TPR_2 PF07719.17 KER32493.1 - 6.9e-24 82.0 45.7 0.0013 18.7 0.0 17.6 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_14 PF13428.6 KER32493.1 - 7e-20 70.0 43.0 0.00056 20.5 0.0 16.5 14 2 3 17 17 15 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER32493.1 - 9.2e-18 62.9 31.0 0.0016 18.5 0.5 14.3 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 KER32493.1 - 1.1e-15 56.7 26.1 0.036 13.9 0.0 13.0 14 0 0 14 14 13 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KER32493.1 - 2.3e-15 56.6 44.0 4.6e-05 23.5 0.2 11.3 8 3 4 12 12 12 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KER32493.1 - 1.1e-13 51.2 51.2 0.018 15.3 0.2 13.2 10 4 2 13 13 13 7 Tetratricopeptide repeat TPR_6 PF13174.6 KER32493.1 - 1.3e-11 44.3 35.7 0.095 13.4 0.0 15.2 17 0 0 17 17 14 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER32493.1 - 1.6e-11 44.7 32.6 0.002 18.7 0.0 10.0 9 2 3 12 12 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 KER32493.1 - 1.1e-08 34.8 3.5 27 5.8 0.0 8.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER32493.1 - 1.1e-08 34.4 26.3 1.2 9.3 0.0 12.8 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER32493.1 - 8.9e-07 28.9 21.3 0.042 14.2 0.0 10.3 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER32493.1 - 7.7e-06 26.0 21.0 0.14 12.3 0.0 9.5 9 2 2 11 11 9 2 Tetratricopeptide repeat NARP1 PF12569.8 KER32493.1 - 1.7e-05 24.0 11.5 0.12 11.3 0.0 6.2 6 1 0 6 6 6 1 NMDA receptor-regulated protein 1 FAT PF02259.23 KER32493.1 - 0.0077 15.5 11.1 0.25 10.5 3.5 4.3 3 1 0 3 3 3 1 FAT domain TPR_15 PF13429.6 KER32493.1 - 0.012 14.8 22.7 0.079 12.2 0.8 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 KER32493.1 - 0.03 13.8 4.4 0.37 10.2 0.3 3.8 3 0 0 3 3 3 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ RPN7 PF10602.9 KER32493.1 - 0.044 13.5 9.9 0.55 9.9 0.1 5.4 6 1 1 7 7 6 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 KER32493.1 - 0.045 14.1 24.1 17 5.8 0.2 9.6 7 2 4 11 11 9 0 Tetratricopeptide repeat DUF4919 PF16266.5 KER32493.1 - 0.082 12.8 0.6 9.7 6.1 0.0 3.5 3 1 1 4 4 3 0 Domain of unknown function (DUF4919) BTAD PF03704.17 KER32493.1 - 0.16 12.4 22.8 0.37 11.2 1.5 5.9 4 1 1 6 6 6 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KER32493.1 - 0.18 11.8 20.7 6.6 6.8 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF627 PF04781.12 KER32493.1 - 0.23 11.5 3.0 5.1 7.2 0.1 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF627) TPR_11 PF13414.6 KER32493.1 - 1 9.1 0.0 1 9.1 0.0 10.0 11 2 2 13 13 13 0 TPR repeat WD40 PF00400.32 KER32494.1 - 4.4e-06 27.3 5.9 0.018 15.9 0.3 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat Peptidase_M1 PF01433.20 KER32495.1 - 1.4e-42 145.7 0.0 2.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KER32495.1 - 3.3e-27 94.8 0.2 6.6e-27 93.8 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KER32495.1 - 3.5e-25 89.3 0.0 5.3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KER32495.1 - 0.029 14.0 0.2 0.072 12.8 0.2 1.6 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KER32495.1 - 0.072 13.5 1.5 1.4 9.3 1.5 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase 7tm_1 PF00001.21 KER32496.1 - 3.2e-20 72.6 22.2 8.3e-20 71.2 22.2 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KER32496.1 - 1.2e-06 28.5 17.8 1.7e-06 28.0 17.8 1.2 1 0 0 1 1 1 1 Olfactory receptor CbtA PF09490.10 KER32496.1 - 0.82 9.4 4.7 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Casc1_N PF15927.5 KER32497.1 - 3.4e-48 164.0 22.3 3.4e-48 164.0 22.3 2.4 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus Flagellar_rod PF05149.12 KER32497.1 - 3.5 7.0 27.0 1.4 8.3 20.0 2.4 2 0 0 2 2 2 0 Paraflagellar rod protein MAJIN PF15077.6 KER32497.1 - 8 6.2 13.4 5.6 6.7 7.3 2.5 2 0 0 2 2 2 0 Membrane-anchored junction protein ThiP_synth PF10120.9 KER32498.1 - 0.093 12.3 0.0 0.093 12.3 0.0 1.0 1 0 0 1 1 1 0 Thiamine-phosphate synthase zf-C4 PF00105.18 KER32499.1 - 2.3e-32 111.2 14.0 4.2e-32 110.4 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER32499.1 - 1.1e-14 54.5 0.3 2e-14 53.6 0.3 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SAM_1 PF00536.30 KER32500.1 - 3.4e-14 53.0 0.1 4.9e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER32500.1 - 6.5e-13 48.6 0.0 1.1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KER32500.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain GIY-YIG PF01541.24 KER32502.1 - 0.0077 16.5 0.2 0.0077 16.5 0.2 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain LRR_8 PF13855.6 KER32503.1 - 4.4e-19 68.0 19.2 1.4e-08 34.4 7.7 3.6 2 1 1 3 3 3 3 Leucine rich repeat ig PF00047.25 KER32503.1 - 7.2e-13 48.5 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KER32503.1 - 4.4e-11 43.2 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 KER32503.1 - 4.6e-10 39.4 0.0 8.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 KER32503.1 - 3.4e-09 36.8 15.0 0.0027 18.1 0.9 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER32503.1 - 4.8e-07 29.4 12.0 4.8 8.1 0.0 6.1 5 0 0 5 5 5 2 Leucine Rich Repeat Ig_2 PF13895.6 KER32503.1 - 8.3e-06 26.0 0.0 2.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER32503.1 - 0.00058 20.0 0.1 0.0054 16.9 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain TPKR_C2 PF16920.5 KER32503.1 - 0.041 14.0 0.9 0.15 12.3 0.4 2.2 2 0 0 2 2 2 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_5 PF13306.6 KER32503.1 - 0.044 13.7 0.4 0.2 11.6 0.2 2.0 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Izumo-Ig PF16706.5 KER32503.1 - 0.064 13.3 1.4 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain MFS_Mycoplasma PF07672.13 KER32503.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Ig_6 PF18452.1 KER32503.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain LRR_9 PF14580.6 KER32503.1 - 0.68 9.4 5.2 1.5 8.3 1.9 2.2 1 1 2 3 3 3 0 Leucine-rich repeat HECT PF00632.25 KER32505.1 - 5.7e-94 315.0 0.1 8.9e-94 314.4 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KER32505.1 - 6.6e-78 262.3 0.1 6.6e-78 262.3 0.1 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) UBM PF14377.6 KER32505.1 - 3e-26 90.0 13.4 2.7e-10 39.3 0.4 4.1 3 1 0 3 3 3 3 Ubiquitin binding region WWE PF02825.20 KER32505.1 - 8.5e-09 35.9 0.0 2.5e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 WWE domain UBA PF00627.31 KER32505.1 - 1e-06 28.5 1.3 4.7e-06 26.4 0.3 2.5 2 0 0 2 2 2 1 UBA/TS-N domain E3_UbLigase_EDD PF11547.8 KER32505.1 - 0.094 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Mpp10 PF04006.12 KER32505.1 - 5.4 5.3 13.1 11 4.3 13.1 1.5 1 0 0 1 1 1 0 Mpp10 protein RVT_1 PF00078.27 KER32506.1 - 2.6e-15 56.5 0.0 1e-14 54.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KER32509.1 - 2.5e-41 141.6 0.0 4e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Polyketide_cyc PF03364.20 KER32509.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Nudc_N PF14050.6 KER32511.1 - 1.9e-24 85.4 0.1 3.2e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 KER32511.1 - 7.8e-10 39.6 0.2 1.4e-09 38.8 0.2 1.4 1 0 0 1 1 1 1 CS domain SRP-alpha_N PF04086.13 KER32511.1 - 0.45 10.4 7.4 0.2 11.6 2.4 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-C4H2 PF10146.9 KER32512.1 - 1.5e-25 90.8 10.3 1.6e-25 90.7 9.3 1.4 1 1 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 KER32512.1 - 0.022 14.8 2.7 0.06 13.4 2.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KER32512.1 - 0.083 12.8 4.1 0.18 11.7 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KER32512.1 - 0.11 12.1 2.8 0.25 11.0 2.3 1.7 2 0 0 2 2 2 0 P-11 zinc finger Penaeidin PF05927.11 KER32512.1 - 0.33 11.7 6.1 7.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Penaeidin RecR PF02132.15 KER32512.1 - 6.6 6.4 6.9 0.99 9.0 2.2 2.0 2 0 0 2 2 2 0 RecR protein FERM_M PF00373.18 KER32515.1 - 4.1e-32 111.1 0.0 7.9e-32 110.1 0.0 1.5 1 1 0 1 1 1 1 FERM central domain Kindlin_2_N PF18124.1 KER32515.1 - 2.7e-26 91.6 0.6 5.8e-26 90.5 0.6 1.6 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain PH PF00169.29 KER32515.1 - 5.9e-06 26.7 0.1 1.1e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 PH domain FERM_N PF09379.10 KER32515.1 - 0.012 15.5 0.0 0.069 13.1 0.0 2.2 1 1 0 1 1 1 0 FERM N-terminal domain I-EGF_1 PF18372.1 KER32518.1 - 8.6e-08 32.1 14.4 0.00012 22.1 0.5 2.5 2 0 0 2 2 2 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 KER32518.1 - 2.8e-05 24.4 20.9 0.00021 21.6 11.1 2.6 2 0 0 2 2 2 2 EGF-like domain RHS PF03527.14 KER32518.1 - 6.5e-05 22.6 0.0 0.00028 20.6 0.0 2.2 1 0 0 1 1 1 1 RHS protein RHS_repeat PF05593.14 KER32518.1 - 0.084 13.4 13.3 9.4 6.9 0.2 7.9 9 0 0 9 9 9 0 RHS Repeat Laminin_EGF PF00053.24 KER32518.1 - 0.3 11.3 16.0 3.1 8.0 1.4 2.6 1 1 0 2 2 2 0 Laminin EGF domain BSP_II PF05432.11 KER32518.1 - 0.64 9.7 3.7 1 9.0 3.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) EGF PF00008.27 KER32518.1 - 4.2 7.8 15.6 0.14 12.5 8.9 2.0 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 KER32518.1 - 9.6 6.4 9.9 3 8.0 4.7 2.5 2 0 0 2 2 2 0 Tenascin EGF domain Nse4-Nse3_bdg PF15412.6 KER32519.1 - 0.097 12.8 0.1 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE EMP70 PF02990.16 KER32521.1 - 2.3e-151 505.0 23.0 2.3e-151 505.0 23.0 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 Shisa PF13908.6 KER32521.1 - 0.078 13.2 0.5 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Cadherin_C_2 PF16492.5 KER32521.1 - 2.1 9.1 7.5 7.9 7.3 0.0 3.6 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal TMEM192 PF14802.6 KER32521.1 - 2.8 7.0 0.0 2.8 7.0 0.0 3.5 3 2 1 4 4 4 0 TMEM192 family COMMD1_N PF17221.3 KER32522.1 - 0.056 13.8 0.0 0.063 13.6 0.0 1.0 1 0 0 1 1 1 0 COMMD1 N-terminal domain Opacity PF02462.15 KER32522.1 - 0.09 12.9 0.0 0.093 12.8 0.0 1.1 1 0 0 1 1 1 0 Opacity family porin protein Spc7 PF08317.11 KER32524.1 - 0.024 13.6 5.4 0.11 11.4 1.6 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 KER32524.1 - 0.066 13.5 3.1 3.8 7.8 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 KER32524.1 - 0.25 11.5 2.5 9.8 6.3 0.1 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DMPK_coil PF08826.10 KER32524.1 - 1.4 9.1 6.1 2.2 8.4 2.3 3.1 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF1664 PF07889.12 KER32524.1 - 2.5 8.1 5.0 12 5.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 KER32524.1 - 3.1 7.9 7.5 1.1 9.4 0.9 3.2 3 0 0 3 3 3 0 RasGAP C-terminus RNR_Alpha PF17975.1 KER32525.1 - 0.061 13.8 0.3 8.2 7.0 0.0 2.6 2 1 1 3 3 3 0 Ribonucleotide reductase alpha domain TAFII28 PF04719.14 KER32527.1 - 2.2e-34 117.4 0.1 4.3e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Myc_N PF01056.18 KER32527.1 - 0.019 14.9 3.4 0.023 14.6 3.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CBFD_NFYB_HMF PF00808.23 KER32527.1 - 0.051 13.9 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC45 PF02724.14 KER32527.1 - 0.11 10.8 2.9 0.12 10.6 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 KER32527.1 - 2 7.7 9.9 3.3 7.0 9.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cytomega_UL84 PF06284.11 KER32527.1 - 2.7 6.4 6.2 3.8 5.9 6.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TFIIE-A_C PF11521.8 KER32527.1 - 7 7.0 14.2 15 5.9 14.2 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Tim54 PF11711.8 KER32527.1 - 9.6 4.9 8.2 21 3.8 5.6 1.8 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 RVT_1 PF00078.27 KER32528.1 - 2.2e-31 109.1 0.0 6.8e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.6 KER32528.1 - 4.8e-11 42.8 4.3 1.8e-10 41.0 4.3 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KER32528.1 - 7.9e-08 32.0 2.7 1.7e-07 31.0 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER32528.1 - 1.1e-06 28.4 0.9 2.5e-06 27.3 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER32528.1 - 3.3e-06 26.9 0.8 9.2e-06 25.5 0.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KER32528.1 - 1e-05 25.7 7.0 3.9e-05 23.9 7.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KER32528.1 - 1.7e-05 24.5 2.4 4.2e-05 23.2 2.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KER32528.1 - 0.0017 18.1 5.0 0.0037 17.1 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KER32528.1 - 0.0041 16.7 5.8 0.0093 15.6 5.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KER32528.1 - 0.0054 16.7 3.5 0.016 15.3 3.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KER32528.1 - 0.017 15.1 3.7 0.057 13.5 3.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Syja_N PF02383.18 KER32529.1 - 6.8e-79 265.5 0.0 1.6e-78 264.2 0.0 1.7 1 1 0 1 1 1 1 SacI homology domain Glyco_hydro_14 PF01373.17 KER32531.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 7tm_1 PF00001.21 KER32532.1 - 9.4e-67 225.1 7.1 1.4e-36 126.1 3.0 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER32532.1 - 1.1e-19 70.8 4.6 2.1e-14 53.5 1.8 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER32532.1 - 1.1e-06 28.5 7.3 1.1e-06 28.5 7.3 3.0 3 1 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 KER32532.1 - 0.0012 18.2 4.2 0.026 13.8 0.0 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Beta-APP PF03494.13 KER32532.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) 7tm_4 PF13853.6 KER32532.1 - 0.51 10.0 5.9 1.8 8.2 2.4 2.3 2 0 0 2 2 2 0 Olfactory receptor SMC_N PF02463.19 KER32533.1 - 8.9e-51 172.4 65.4 7.3e-50 169.4 65.4 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KER32533.1 - 1.6e-21 76.8 0.0 6.2e-21 74.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KER32533.1 - 2.6e-18 67.3 13.2 2.6e-18 67.3 13.2 7.1 2 2 3 5 5 2 1 AAA domain Exo_endo_phos_2 PF14529.6 KER32533.1 - 6.7e-13 48.5 0.0 3.7e-12 46.2 0.0 2.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AAA_15 PF13175.6 KER32533.1 - 7e-13 49.0 11.4 7e-13 49.0 11.4 4.3 2 2 1 4 4 3 2 AAA ATPase domain AAA_21 PF13304.6 KER32533.1 - 8.3e-10 39.0 26.7 3.9e-06 26.9 3.2 4.5 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KER32533.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KER32533.1 - 0.0089 16.0 0.1 7.6 6.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.18 KER32533.1 - 0.016 14.5 2.6 0.15 11.4 0.0 3.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family YlbE PF14003.6 KER32533.1 - 0.08 13.4 1.7 3.7 8.0 1.3 4.0 2 0 0 2 2 2 0 YlbE-like protein Podoplanin PF05808.11 KER32533.1 - 0.1 12.7 1.3 0.36 10.9 1.3 1.9 1 0 0 1 1 1 0 Podoplanin DUF2371 PF10177.9 KER32534.1 - 0.019 15.2 0.2 0.037 14.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) EGF PF00008.27 KER32534.1 - 0.035 14.4 6.1 0.035 14.4 6.1 2.6 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.7 KER32534.1 - 6.3 7.6 8.6 6.7 7.5 4.0 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF Pkinase PF00069.25 KER32535.1 - 1.8e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain KA1 PF02149.19 KER32535.1 - 0.00057 19.6 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 Kinase associated domain 1 Pkinase_Tyr PF07714.17 KER32535.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KER32537.1 - 2.2e-42 145.3 0.1 2.8e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32537.1 - 7.9e-25 87.6 0.1 1e-24 87.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER32537.1 - 8e-06 25.9 0.3 0.00031 20.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER32537.1 - 0.0085 15.1 0.1 0.012 14.6 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER32537.1 - 0.025 13.9 0.2 0.044 13.1 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KER32537.1 - 0.034 13.7 0.1 0.1 12.2 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase SNF PF00209.18 KER32539.1 - 2e-150 501.9 17.2 4.5e-139 464.5 16.6 3.5 3 1 0 3 3 3 3 Sodium:neurotransmitter symporter family RVT_1 PF00078.27 KER32541.1 - 4.9e-13 49.1 0.0 7.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.31 KER32545.1 - 2.9e-20 72.2 0.7 9.9e-19 67.2 0.7 2.4 1 1 0 1 1 1 1 DnaJ domain Comm PF15957.5 KER32545.1 - 0.078 13.3 3.7 7.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Commissureless ATP-synt_C PF00137.21 KER32546.1 - 1.1e-10 41.6 12.6 1.6e-10 41.1 12.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Phage_holin_3_6 PF07332.11 KER32546.1 - 0.42 10.7 5.2 0.87 9.7 5.2 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RVT_1 PF00078.27 KER32547.1 - 0.003 17.1 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FYVE PF01363.21 KER32548.1 - 4.1e-17 62.1 6.0 4.1e-17 62.1 6.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 KER32548.1 - 7.4e-08 32.8 0.1 0.00055 20.4 0.0 3.0 3 0 0 3 3 3 2 PH domain RhoGEF PF00621.20 KER32548.1 - 2.7e-07 31.0 1.6 5.1e-07 30.1 1.6 1.4 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 KER32548.1 - 0.0026 17.7 0.1 0.0052 16.7 0.1 1.4 1 0 0 1 1 1 1 PH domain ENTH PF01417.20 KER32548.1 - 0.047 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 ENTH domain FYVE_2 PF02318.16 KER32548.1 - 0.35 11.1 8.1 0.093 13.0 2.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 KER32548.1 - 0.65 10.0 5.1 0.66 10.0 1.5 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LRR_8 PF13855.6 KER32550.1 - 1.3e-57 191.4 51.1 4.7e-13 48.7 1.3 8.6 6 1 4 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 KER32550.1 - 1.1e-38 130.5 53.9 2e-06 28.0 4.4 11.4 5 3 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER32550.1 - 1.6e-09 37.0 63.4 3.6 8.5 0.2 17.6 17 3 1 18 18 18 6 Leucine Rich Repeat LRR_9 PF14580.6 KER32550.1 - 3.9e-09 36.3 28.6 0.025 14.1 2.0 6.1 2 2 4 6 6 6 6 Leucine-rich repeat LRR_5 PF13306.6 KER32550.1 - 0.016 15.2 0.2 3.4 7.6 0.1 3.4 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) CSTF_C PF14304.6 KER32550.1 - 0.21 11.2 11.4 4 7.1 0.1 5.9 7 0 0 7 7 7 0 Transcription termination and cleavage factor C-terminal AAA PF00004.29 KER32555.1 - 3.6e-06 27.4 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 KER32555.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_14 PF13173.6 KER32555.1 - 0.0026 17.8 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KER32555.1 - 0.0035 17.3 0.0 0.0095 15.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KER32555.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KER32555.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KER32555.1 - 0.017 15.4 0.0 0.53 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KER32555.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KER32555.1 - 0.02 14.5 0.0 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KER32555.1 - 0.036 14.4 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 KER32555.1 - 0.038 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER32555.1 - 0.087 12.8 0.1 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KER32555.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KER32555.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein HTH_32 PF13565.6 KER32555.1 - 0.13 12.8 1.9 0.45 11.2 1.9 1.9 1 0 0 1 1 1 0 Homeodomain-like domain UPF0489 PF12640.7 KER32556.1 - 3.1e-33 115.5 0.1 7e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain FYVE PF01363.21 KER32558.1 - 1.7e-19 69.7 13.0 1.7e-19 69.7 13.0 2.4 4 0 0 4 4 2 1 FYVE zinc finger TEX13 PF15186.6 KER32558.1 - 0.0014 18.3 8.4 0.0014 18.3 8.4 5.3 3 2 3 6 6 6 1 Testis-expressed sequence 13 protein family Fez1 PF06818.15 KER32558.1 - 0.01 16.3 49.6 0.013 15.9 11.5 3.5 2 1 2 4 4 4 0 Fez1 zf_C2H2_ZHX PF18387.1 KER32558.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KER32558.1 - 0.41 11.6 0.1 0.41 11.6 0.1 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger HSA PF07529.13 KER32558.1 - 0.92 9.9 5.5 17 5.8 1.5 3.3 2 1 1 3 3 3 0 HSA DUF1664 PF07889.12 KER32558.1 - 1.9 8.5 27.4 1.3 9.1 2.7 4.6 3 3 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KER32558.1 - 2.5 6.6 36.3 7e+02 -1.5 36.3 3.0 1 1 0 1 1 1 0 AAA domain HMMR_N PF15905.5 KER32558.1 - 2.8 7.3 50.0 2 7.8 7.4 3.4 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal CCDC144C PF14915.6 KER32558.1 - 3.8 6.5 51.3 0.56 9.3 19.5 3.5 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 KER32558.1 - 4.6 6.0 52.2 0.2 10.5 18.4 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KER32558.1 - 5.8 6.8 7.2 0.79 9.6 0.3 3.4 3 0 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Zn-ribbon_8 PF09723.10 KER32558.1 - 9.2 6.5 12.7 28 4.9 5.3 3.7 2 1 2 4 4 4 0 Zinc ribbon domain DUF573 PF04504.14 KER32558.1 - 9.7 6.9 8.5 4.9 7.9 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF573 WD40 PF00400.32 KER32559.1 - 1.4e-07 32.0 6.3 0.34 11.9 0.1 6.5 6 0 0 6 6 6 1 WD domain, G-beta repeat Mt_ATP_synt PF15704.5 KER32559.1 - 6.8e-06 26.1 7.1 0.019 14.9 0.5 2.3 2 0 0 2 2 2 2 Mitochondrial ATP synthase subunit Nterm_IS4 PF13006.7 KER32559.1 - 0.0076 16.4 0.2 7.4 6.9 0.0 2.6 2 0 0 2 2 2 2 Insertion element 4 transposase N-terminal DUF3811 PF11656.8 KER32559.1 - 0.042 14.2 1.5 21 5.6 0.0 3.9 4 0 0 4 4 4 0 YjbD family (DUF3811) DUF3565 PF12088.8 KER32559.1 - 0.11 12.5 0.2 29 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) ISG65-75 PF11727.8 KER32559.1 - 0.23 10.6 3.6 7.7 5.7 0.2 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein UPF0242 PF06785.11 KER32559.1 - 0.87 9.7 11.3 2.1 8.4 1.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Acyl-CoA_ox_N PF14749.6 KER32559.1 - 5 7.7 6.6 30 5.2 0.7 2.4 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal BEN PF10523.9 KER32560.1 - 0.043 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 BEN domain Snapin_Pallidin PF14712.6 KER32561.1 - 0.074 13.5 0.7 6.3 7.3 0.7 2.3 2 0 0 2 2 2 0 Snapin/Pallidin RNA_pol_L_2 PF13656.6 KER32564.1 - 3.7e-25 87.5 0.0 5.4e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KER32564.1 - 1.7e-06 27.3 0.0 2.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GYF PF02213.16 KER32565.1 - 0.00073 19.2 0.4 0.0016 18.0 0.0 1.9 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 KER32565.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 GYF domain 2 Glyco_hydro_47 PF01532.20 KER32566.1 - 1.7e-109 366.8 0.0 3.3e-109 365.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Methyltransf_4 PF02390.17 KER32567.1 - 1.6e-43 148.2 0.0 3.1e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 KER32567.1 - 0.0011 18.8 0.1 0.0062 16.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Syntaxin PF00804.25 KER32567.1 - 0.0015 18.3 1.6 0.015 15.0 0.2 2.3 2 0 0 2 2 2 1 Syntaxin Methyltransf_12 PF08242.12 KER32567.1 - 0.0026 18.5 0.0 0.0078 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER32567.1 - 0.0048 17.6 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SNARE PF05739.19 KER32567.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KER32567.1 - 0.011 14.9 0.1 0.031 13.5 0.1 1.8 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain Methyltransf_11 PF08241.12 KER32567.1 - 0.071 13.8 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KER32567.1 - 0.081 12.9 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KER32567.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 KER32567.1 - 0.18 11.3 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 IBR PF01485.21 KER32568.1 - 4.8e-25 87.6 37.1 3.4e-14 52.8 7.3 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KER32568.1 - 0.014 15.2 0.8 0.014 15.2 0.8 4.9 3 1 2 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER32568.1 - 0.023 14.6 1.2 0.023 14.6 1.2 4.2 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_14 PF17978.1 KER32568.1 - 0.031 14.7 0.4 0.031 14.7 0.4 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KER32568.1 - 0.044 13.6 0.5 0.044 13.6 0.5 5.2 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER32568.1 - 0.071 13.2 0.7 0.071 13.2 0.7 4.5 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 KER32568.1 - 5.3 7.5 36.5 0.34 11.3 1.8 4.7 3 1 1 4 4 4 0 Ring finger domain IRS PF02174.17 KER32569.1 - 5.7e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) DUF4218 PF13960.6 KER32571.1 - 0.00069 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1258 PF06869.12 KER32571.1 - 0.0071 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) TSNAXIP1_N PF15739.5 KER32572.1 - 1.6e-18 67.1 4.2 1.6e-18 67.1 4.2 3.9 2 1 1 4 4 4 1 Translin-associated factor X-interacting N-terminus Spc7 PF08317.11 KER32572.1 - 0.00041 19.3 29.5 0.033 13.1 9.7 3.4 1 1 2 3 3 3 3 Spc7 kinetochore protein HAP1_N PF04849.13 KER32572.1 - 0.0066 15.7 27.9 0.057 12.6 13.1 2.6 2 0 0 2 2 2 2 HAP1 N-terminal conserved region DUF16 PF01519.16 KER32572.1 - 0.7 10.4 17.3 3.5 8.2 2.7 3.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 ADIP PF11559.8 KER32572.1 - 1 9.4 23.6 1.3 9.1 12.8 3.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CC2-LZ PF16516.5 KER32572.1 - 6.3 7.2 26.3 0.24 11.8 4.9 4.3 2 1 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Asp PF00026.23 KER32574.1 - 1.8e-97 326.6 0.1 1.1e-60 205.7 0.4 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER32574.1 - 3.2e-13 50.3 0.9 1e-10 42.2 0.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.12 KER32574.1 - 1.9e-05 24.4 0.2 4.8e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.6 KER32574.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Acyl-CoA_dh_1 PF00441.24 KER32575.1 - 2.4e-39 135.0 0.1 3.2e-39 134.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KER32575.1 - 1.2e-27 95.9 0.0 2.1e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KER32575.1 - 4.3e-22 78.9 0.0 1.1e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KER32575.1 - 4.6e-06 27.0 0.0 7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KER32575.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GatB_N PF02934.15 KER32576.1 - 8.3e-96 320.6 0.0 1.2e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KER32576.1 - 1.5e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 GatB domain Cadherin PF00028.17 KER32577.1 - 2.3e-67 223.5 0.6 1.3e-16 60.8 0.0 8.8 6 2 1 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 KER32577.1 - 1.9e-08 34.0 0.1 0.45 10.4 0.0 6.1 6 1 0 6 6 6 3 Cadherin-like RET_CLD1 PF17756.1 KER32577.1 - 0.0043 17.3 0.0 0.22 11.8 0.0 2.9 3 0 0 3 3 3 1 RET Cadherin like domain 1 Polysacc_syn_2C PF08485.10 KER32577.1 - 0.036 13.7 0.4 0.31 10.8 0.1 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal DUF2568 PF10823.8 KER32578.1 - 0.013 15.8 1.0 0.013 15.8 1.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2568) YqzM PF14141.6 KER32578.1 - 0.066 13.3 2.1 0.26 11.4 2.1 2.0 1 0 0 1 1 1 0 YqzM-like protein EAR PF07897.11 KER32579.1 - 0.017 14.8 0.5 0.04 13.5 0.5 1.6 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression RVT_1 PF00078.27 KER32579.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S13 PF00416.22 KER32581.1 - 9.9e-53 177.9 3.1 1.2e-52 177.6 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Period_C PF12114.8 KER32581.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Tektin PF03148.14 KER32582.1 - 9.4e-89 297.8 46.4 5.2e-78 262.5 21.1 4.1 4 0 0 4 4 4 4 Tektin family DUF4239 PF14023.6 KER32582.1 - 0.34 10.6 6.0 0.92 9.2 6.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) AKNA PF12443.8 KER32582.1 - 1.6 9.4 7.7 0.66 10.7 2.0 3.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF641 PF04859.12 KER32582.1 - 5.2 7.4 17.8 0.023 15.0 4.4 3.6 5 0 0 5 5 5 0 Plant protein of unknown function (DUF641) Cadherin PF00028.17 KER32583.1 - 5.1e-33 113.4 0.8 3e-17 62.8 0.1 7.1 8 1 0 8 8 8 5 Cadherin domain Cadherin_2 PF08266.12 KER32583.1 - 0.0015 18.4 0.6 1.4 8.8 0.0 4.2 3 1 0 3 3 3 2 Cadherin-like YueH PF14166.6 KER32583.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 YueH-like protein Cadherin PF00028.17 KER32584.1 - 1.1e-13 51.4 0.4 0.0014 19.1 0.0 3.9 3 1 0 3 3 3 3 Cadherin domain LRR_4 PF12799.7 KER32585.1 - 4.6e-05 23.7 3.3 0.0049 17.2 3.3 2.8 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER32585.1 - 0.038 13.7 2.0 0.29 10.9 2.0 2.3 1 1 0 1 1 1 0 Leucine rich repeat MULE PF10551.9 KER32586.1 - 0.0017 18.8 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 MULE transposase domain RRM_1 PF00076.22 KER32588.1 - 1.1e-33 114.9 0.2 6.3e-16 57.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER32588.1 - 2.4e-11 43.6 0.1 1.5e-06 28.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RL PF17797.1 KER32588.1 - 0.0049 16.8 0.0 5.7 7.0 0.0 2.8 2 0 0 2 2 2 2 RL domain Actin PF00022.19 KER32590.1 - 4.9e-130 433.8 0.0 9.2e-130 432.9 0.0 1.4 1 1 0 1 1 1 1 Actin Cation_ATPase_C PF00689.21 KER32593.1 - 8.8e-43 146.1 8.0 8.8e-43 146.1 8.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KER32593.1 - 2.7e-35 121.5 4.8 1e-25 90.3 0.2 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 KER32593.1 - 6.2e-18 64.7 0.0 1.6e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KER32593.1 - 3.7e-15 55.3 0.0 3e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KER32593.1 - 5.6e-15 56.2 0.0 1.6e-11 44.9 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 KER32593.1 - 2e-11 44.2 0.3 7.1e-11 42.4 0.3 2.0 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 KER32593.1 - 4.8e-07 29.8 0.6 3.4e-05 23.7 0.1 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.8 KER32593.1 - 0.028 14.2 8.1 0.63 9.9 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3619 PF12279.8 KER32593.1 - 0.3 11.4 1.5 23 5.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) DUF4231 PF14015.6 KER32593.1 - 4.3 7.9 7.8 1.1 9.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Pox_EPC_I2-L1 PF12575.8 KER32593.1 - 5 7.4 10.4 44 4.4 0.0 4.2 4 0 0 4 4 3 0 Poxvirus entry protein complex L1 and I2 Shisa PF13908.6 KER32597.1 - 0.00013 22.3 0.0 0.00016 22.0 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tweety PF04906.13 KER32597.1 - 0.0026 16.5 0.2 0.0034 16.1 0.2 1.1 1 0 0 1 1 1 1 Tweety WBP-1 PF11669.8 KER32597.1 - 0.019 15.6 0.3 0.057 14.1 0.3 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 ETRAMP PF09716.10 KER32597.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MLANA PF14991.6 KER32597.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A HPD PF05044.12 KER32599.1 - 1.7e-34 118.9 0.2 7.1e-33 113.7 0.2 2.4 1 1 0 1 1 1 1 Homeo-prospero domain PID PF00640.23 KER32600.1 - 1.7e-26 92.9 1.0 2.8e-26 92.2 1.0 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 KER32600.1 - 1.6e-19 70.2 0.6 7.3e-19 68.1 0.6 2.1 1 0 0 1 1 1 1 NUMB domain PID_2 PF14719.6 KER32600.1 - 0.0016 18.3 0.3 0.0055 16.6 0.3 1.8 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) EPL1 PF10513.9 KER32603.1 - 1.3e-10 41.9 1.2 1.7e-10 41.5 0.2 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like CDC50 PF03381.15 KER32604.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2228 PF10228.9 KER32605.1 - 3.6e-56 190.7 0.0 4.4e-55 187.2 0.0 2.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Tn7_Tnp_TnsA_C PF08721.11 KER32605.1 - 0.002 18.8 0.2 0.41 11.3 0.0 2.7 2 0 0 2 2 2 2 TnsA endonuclease C terminal VPS9 PF02204.18 KER32609.1 - 8.1e-18 64.6 0.0 2e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 KER32609.1 - 0.12 12.1 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase RAB3GAP2_N PF14655.6 KER32610.1 - 7.4e-43 147.3 0.6 1.5e-23 83.8 0.0 2.2 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 KER32610.1 - 2.5e-33 115.2 0.0 1.3e-18 66.6 0.0 2.6 2 1 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus GvpG PF05120.12 KER32612.1 - 0.47 10.5 3.3 0.87 9.6 0.1 2.7 2 0 0 2 2 2 0 Gas vesicle protein G ACR_tran PF00873.19 KER32612.1 - 0.5 7.9 5.2 1.1 6.8 5.2 1.5 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FAM91_C PF14648.6 KER32614.1 - 4.8e-142 473.8 0.0 6.1e-142 473.5 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 KER32614.1 - 3.9e-107 358.1 0.2 5.9e-107 357.5 0.2 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Helicase_C PF00271.31 KER32615.1 - 6.2e-32 110.2 0.1 8.1e-31 106.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KER32615.1 - 7.8e-28 97.4 0.0 1.1e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med3 PF11593.8 KER32615.1 - 0.035 13.3 0.6 0.059 12.6 0.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA-synt_1b PF00579.25 KER32615.1 - 0.044 13.1 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ecl1 PF12855.7 KER32615.1 - 1.3 10.2 11.2 2.3 9.4 11.2 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins PUB PF09409.10 KER32617.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 PUB domain Pkinase PF00069.25 KER32619.1 - 6.8e-65 219.0 0.0 8.4e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32619.1 - 1.5e-33 116.2 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KER32619.1 - 0.0014 18.6 0.1 0.0039 17.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KER32619.1 - 0.004 16.1 0.4 0.0056 15.7 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KER32619.1 - 0.0043 15.9 0.1 0.0063 15.4 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Pkinase_fungal PF17667.1 KER32619.1 - 0.12 11.2 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RVT_1 PF00078.27 KER32620.1 - 1.7e-24 86.6 0.0 1.2e-14 54.4 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2829 PF11195.8 KER32620.1 - 0.14 12.4 0.0 29 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) Sm_like PF16243.5 KER32620.1 - 0.17 12.0 0.0 18 5.6 0.0 2.4 2 0 0 2 2 2 0 Sm_like domain 7tm_1 PF00001.21 KER32621.1 - 1.8e-10 40.6 0.9 5.2e-08 32.5 0.1 2.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Pkinase_Tyr PF07714.17 KER32623.1 - 4.2e-38 131.1 0.0 1.7e-27 96.4 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER32623.1 - 3.7e-35 121.6 0.0 5.6e-30 104.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KER32623.1 - 0.024 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KER32623.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PseudoU_synth_2 PF00849.22 KER32625.1 - 5.6e-16 59.0 0.0 2e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase CdhC PF03598.15 KER32627.1 - 0.022 14.6 0.2 0.027 14.3 0.2 1.3 1 1 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Apolipoprotein PF01442.18 KER32629.1 - 9.9e-05 22.3 9.3 9.9e-05 22.3 9.3 5.4 3 1 2 5 5 5 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 KER32629.1 - 1.5 9.2 15.2 9.9 6.5 0.1 5.6 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) SNAD4 PF18750.1 KER32630.1 - 0.14 12.3 0.4 0.18 12.0 0.4 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CH PF00307.31 KER32631.1 - 1.4e-10 41.3 0.0 5.7e-09 36.1 0.0 3.7 3 0 0 3 3 3 1 Calponin homology (CH) domain Abi_C PF14355.6 KER32631.1 - 0.009 16.1 0.6 3.6 7.8 0.1 4.7 4 0 0 4 4 4 1 Abortive infection C-terminus TMEM89 PF15098.6 KER32633.1 - 0.078 13.2 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 TMEM89 protein family TRF PF08558.10 KER32633.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Cullin PF00888.22 KER32636.1 - 1.4e-125 420.3 12.3 2e-119 400.0 3.0 2.9 1 1 1 2 2 2 2 Cullin family Methyltransf_28 PF02636.17 KER32636.1 - 4.5e-48 164.2 0.0 9.3e-48 163.1 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-C3HC4_3 PF13920.6 KER32638.1 - 6.8e-05 22.7 11.2 0.00026 20.8 11.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER32638.1 - 0.00045 20.0 11.6 0.00045 20.0 11.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER32638.1 - 0.00085 19.1 11.4 0.00085 19.1 11.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER32638.1 - 0.0012 19.1 13.3 0.0012 19.1 13.3 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KER32638.1 - 0.0094 15.8 10.8 0.0094 15.8 10.8 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-met PF12874.7 KER32638.1 - 0.014 15.8 0.2 0.014 15.8 0.2 2.4 1 1 1 2 2 2 0 Zinc-finger of C2H2 type zf-rbx1 PF12678.7 KER32638.1 - 0.029 14.6 9.0 0.087 13.1 9.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain TMCCDC2 PF15844.5 KER32638.1 - 0.072 13.0 2.9 4.1 7.3 0.2 2.4 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 zf-RING_UBOX PF13445.6 KER32638.1 - 0.15 12.1 10.3 0.45 10.6 7.8 2.8 2 1 0 2 2 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KER32638.1 - 0.18 11.8 11.9 0.74 9.8 11.9 2.2 1 0 0 1 1 1 0 zinc-RING finger domain RNA_pol_I_TF PF04090.12 KER32638.1 - 0.33 10.4 3.2 8.4 5.8 0.3 2.4 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor zf-C2H2_jaz PF12171.8 KER32638.1 - 0.38 11.1 0.1 0.38 11.1 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_10 PF16685.5 KER32638.1 - 1.3 9.2 10.6 0.27 11.4 5.4 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 Peptidase_M50B PF13398.6 KER32638.1 - 1.5 8.4 9.5 2.3 7.8 2.6 2.3 2 0 0 2 2 2 0 Peptidase M50B-like zf-C3HC4_4 PF15227.6 KER32638.1 - 5.3 7.3 14.6 9.2 6.5 11.7 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING CAP_N PF01213.19 KER32640.1 - 1.2e-92 310.8 0.0 2e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KER32640.1 - 3.2e-61 205.5 4.4 5.2e-61 204.9 4.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KER32640.1 - 0.00012 21.7 4.9 0.094 12.4 0.3 2.0 1 1 0 2 2 2 2 Tubulin binding cofactor C Ribosomal_L1 PF00687.21 KER32641.1 - 1.1e-43 149.3 3.4 1.3e-43 149.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GHL13 PF14883.6 KER32641.1 - 0.00082 18.5 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 TetR PF13972.6 KER32641.1 - 0.16 11.7 0.3 0.31 10.7 0.1 1.5 2 0 0 2 2 2 0 Bacterial transcriptional repressor Glyco_hydro_47 PF01532.20 KER32642.1 - 1.1e-96 324.6 0.0 4.3e-95 319.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Cactin_mid PF10312.9 KER32644.1 - 2.1e-58 197.3 0.7 2.1e-58 197.3 0.7 2.7 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KER32644.1 - 1.1e-55 186.8 9.5 2.5e-55 185.7 9.5 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Tim17 PF02466.19 KER32644.1 - 8e-16 58.4 0.2 1.8e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SF3A2 PF16835.5 KER32644.1 - 0.12 12.8 0.6 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Zip PF02535.22 KER32644.1 - 4.7 6.3 11.9 0.073 12.3 3.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter AAA PF00004.29 KER32647.1 - 4.5e-12 46.5 0.0 8.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KER32647.1 - 9.3e-11 42.2 0.0 2.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KER32647.1 - 3.6e-10 40.5 0.2 1.1e-09 38.9 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 KER32647.1 - 1.2e-09 38.0 0.7 8.5e-09 35.3 0.1 2.5 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_5 PF07728.14 KER32647.1 - 8.7e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KER32647.1 - 0.00017 21.1 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 KER32647.1 - 0.00028 21.0 0.6 0.0012 18.9 0.2 2.2 3 0 0 3 3 3 1 AAA lid domain Sigma54_activat PF00158.26 KER32647.1 - 0.0007 19.3 0.2 0.016 15.0 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.6 KER32647.1 - 0.0015 18.8 1.1 0.0061 16.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KER32647.1 - 0.0029 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ORC5_C PF14630.6 KER32647.1 - 0.0067 16.0 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF815 PF05673.13 KER32647.1 - 0.014 14.5 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KER32647.1 - 0.018 15.1 0.1 0.93 9.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 KER32647.1 - 0.019 14.2 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain DUF2075 PF09848.9 KER32647.1 - 0.038 13.2 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KER32647.1 - 0.056 13.2 0.4 3.2 7.5 0.1 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase IBB PF01749.20 KER32647.1 - 0.21 12.1 2.0 0.52 10.8 2.0 1.7 1 0 0 1 1 1 0 Importin beta binding domain Pkinase PF00069.25 KER32648.1 - 3.6e-23 82.3 0.0 2.8e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KER32648.1 - 5.7e-18 65.1 0.1 2.7e-16 59.6 0.0 2.7 1 1 1 2 2 2 1 Protein tyrosine kinase UPF0302 PF08864.10 KER32648.1 - 0.029 14.4 0.2 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 UPF0302 domain Kdo PF06293.14 KER32648.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER32648.1 - 0.096 12.0 0.4 0.57 9.4 0.4 2.2 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KER32649.1 - 1.3e-72 244.4 0.0 1.6e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32649.1 - 1.8e-34 119.2 0.0 2.3e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER32649.1 - 2.4e-09 36.9 0.0 2.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 KER32649.1 - 0.00014 21.3 0.3 0.00029 20.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER32649.1 - 0.0044 16.6 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KER32649.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER32649.1 - 0.019 14.9 0.0 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S13_N PF08069.12 KER32649.1 - 0.11 12.6 0.5 0.41 10.7 0.0 2.2 2 1 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Laminin_II PF06009.12 KER32650.1 - 2.1e-05 24.6 5.9 2.1e-05 24.6 5.9 2.4 3 0 0 3 3 2 1 Laminin Domain II AAA_13 PF13166.6 KER32650.1 - 0.00023 20.0 12.4 0.00031 19.6 12.4 1.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KER32650.1 - 0.0026 18.3 1.0 0.0035 17.9 1.0 1.3 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.9 KER32650.1 - 0.0047 17.2 6.8 0.021 15.1 1.9 2.6 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.9 KER32650.1 - 0.0057 16.1 9.1 0.0089 15.4 9.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Tropomyosin PF00261.20 KER32650.1 - 0.006 16.0 9.0 0.006 16.0 9.0 2.2 1 1 1 2 2 2 1 Tropomyosin ADIP PF11559.8 KER32650.1 - 0.0068 16.5 17.9 0.061 13.4 6.8 2.5 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 KER32650.1 - 0.0085 15.9 6.3 0.0085 15.9 6.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.14 KER32650.1 - 0.0099 15.8 0.9 0.0099 15.8 0.9 2.2 1 1 0 2 2 2 1 Sec8 exocyst complex component specific domain ATG16 PF08614.11 KER32650.1 - 0.013 15.8 21.5 0.05 13.8 21.6 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2203 PF09969.9 KER32650.1 - 0.018 15.8 12.7 0.034 14.9 3.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-C4H2 PF10146.9 KER32650.1 - 0.02 15.2 2.2 0.02 15.2 2.2 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein HrpB7 PF09486.10 KER32650.1 - 0.024 15.0 17.5 0.043 14.2 17.5 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) MAD PF05557.13 KER32650.1 - 0.029 12.7 16.6 0.04 12.3 16.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein UPF0184 PF03670.13 KER32650.1 - 0.031 14.7 1.6 1.8 9.0 0.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.12 KER32650.1 - 0.063 13.7 7.0 0.054 14.0 2.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 KER32650.1 - 0.085 12.4 9.3 0.16 11.5 9.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KER32650.1 - 0.09 11.6 19.2 0.2 10.5 18.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Flagellin_C PF00700.21 KER32650.1 - 0.14 12.5 3.5 0.37 11.2 0.5 3.0 3 1 1 4 4 2 0 Bacterial flagellin C-terminal helical region FliJ PF02050.16 KER32650.1 - 0.2 11.9 10.9 1.9 8.7 1.7 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein LXG PF04740.12 KER32650.1 - 0.21 11.2 8.4 4 7.1 8.4 2.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily Muted PF14942.6 KER32650.1 - 0.21 11.9 11.5 0.33 11.3 10.9 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1515 PF07439.11 KER32650.1 - 0.22 11.6 4.1 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Lebercilin PF15619.6 KER32650.1 - 0.23 11.1 21.5 0.59 9.8 20.8 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KER32650.1 - 0.25 11.9 20.6 0.35 11.4 8.6 2.8 2 1 1 3 3 2 0 Apg6 coiled-coil region Phlebovirus_NSM PF07246.11 KER32650.1 - 0.27 10.6 7.1 0.14 11.5 5.0 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IFT57 PF10498.9 KER32650.1 - 0.28 10.1 9.1 0.4 9.6 9.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KER32650.1 - 0.36 10.9 8.1 2.9 7.9 6.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KER32650.1 - 0.38 8.8 15.9 0.52 8.4 15.9 1.1 1 0 0 1 1 1 0 HOOK protein WDCP PF15390.6 KER32650.1 - 0.41 9.0 5.4 0.54 8.6 5.4 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ERM PF00769.19 KER32650.1 - 0.42 10.4 23.0 2.3 7.9 23.1 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PMEI PF04043.15 KER32650.1 - 0.43 10.9 10.3 0.15 12.4 6.9 1.9 2 1 0 2 2 1 0 Plant invertase/pectin methylesterase inhibitor GAS PF13851.6 KER32650.1 - 0.59 9.4 18.9 0.019 14.3 9.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KER32650.1 - 0.6 8.2 13.0 2.5 6.2 13.0 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 KER32650.1 - 0.63 10.7 20.8 1.5 9.5 11.1 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KER32650.1 - 0.64 9.3 13.3 1.2 8.4 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 KER32650.1 - 0.68 8.7 10.3 0.12 11.2 5.0 2.1 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain Filament PF00038.21 KER32650.1 - 0.75 9.3 15.6 4.1 6.9 14.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein COG2 PF06148.11 KER32650.1 - 0.77 9.8 12.7 2.7 8.1 3.0 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KER32650.1 - 0.84 9.7 4.8 1.7 8.7 3.5 2.2 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.7 KER32650.1 - 0.87 9.1 17.5 2.4 7.6 17.5 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 KER32650.1 - 0.9 9.6 19.5 0.15 12.1 9.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FH2 PF02181.23 KER32650.1 - 0.94 8.5 14.7 0.08 12.0 5.4 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain Fib_alpha PF08702.10 KER32650.1 - 1 9.6 8.5 0.3 11.3 4.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF489 PF04356.12 KER32650.1 - 1.1 9.2 5.7 2.5 8.1 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) ZapB PF06005.12 KER32650.1 - 1.2 9.6 16.6 0.45 11.0 5.0 2.9 2 1 0 2 2 2 0 Cell division protein ZapB Sec34 PF04136.15 KER32650.1 - 1.3 8.9 6.2 5.4 6.9 1.9 2.5 2 1 1 3 3 2 0 Sec34-like family Nup54 PF13874.6 KER32650.1 - 1.3 9.1 11.2 0.88 9.7 8.4 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Snapin_Pallidin PF14712.6 KER32650.1 - 2.1 8.8 9.3 2.7 8.5 5.8 2.6 1 1 1 2 2 2 0 Snapin/Pallidin Hrs_helical PF12210.8 KER32650.1 - 2.5 8.7 10.8 1.9 9.1 3.1 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FlaC_arch PF05377.11 KER32650.1 - 2.6 8.5 9.2 30 5.1 3.7 3.5 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KER32650.1 - 2.7 6.5 12.1 3.2 6.3 10.3 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A GreA_GreB_N PF03449.15 KER32650.1 - 2.9 8.1 7.3 1.2 9.3 0.3 3.0 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal DUF3829 PF12889.7 KER32650.1 - 2.9 7.3 12.3 0.53 9.7 6.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) Allexi_40kDa PF05549.11 KER32650.1 - 3 7.3 5.2 1.8 8.0 2.9 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.12 KER32650.1 - 3.2 7.8 20.8 0.15 12.2 8.4 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.6 KER32650.1 - 3.5 8.0 13.1 0.81 10.1 5.1 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF16 PF01519.16 KER32650.1 - 4.2 7.9 10.2 87 3.7 10.2 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 KER32650.1 - 4.4 7.4 6.8 5.2 7.2 0.2 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation BRE1 PF08647.11 KER32650.1 - 4.5 7.4 19.6 5.2 7.2 9.1 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KER32650.1 - 5.1 7.5 17.8 12 6.3 13.9 2.1 1 1 1 2 2 2 0 Fez1 STAT_alpha PF01017.20 KER32650.1 - 5.3 6.9 9.8 6.6 6.6 3.8 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain Spc24 PF08286.11 KER32650.1 - 5.4 7.3 11.1 0.19 12.0 0.2 2.9 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 HemX PF04375.14 KER32650.1 - 5.5 6.2 16.1 5.1 6.3 3.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Uso1_p115_C PF04871.13 KER32650.1 - 5.5 7.4 24.7 1.7 9.0 10.0 2.5 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4337 PF14235.6 KER32650.1 - 5.6 7.0 12.5 0.053 13.6 1.3 2.1 1 1 0 2 2 1 0 Domain of unknown function (DUF4337) CC2-LZ PF16516.5 KER32650.1 - 5.8 7.4 17.1 0.34 11.3 3.5 3.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YkyA PF10368.9 KER32650.1 - 6.7 6.3 15.8 0.75 9.4 8.4 1.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein SOGA PF11365.8 KER32650.1 - 7.2 7.8 12.3 0.51 11.5 4.2 2.2 1 1 1 2 2 2 0 Protein SOGA Golgin_A5 PF09787.9 KER32650.1 - 8 5.8 14.7 11 5.3 12.9 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 MbeB_N PF04837.12 KER32650.1 - 8.9 6.7 12.4 2.9 8.3 2.8 3.0 2 1 0 2 2 2 0 MbeB-like, N-term conserved region PEARLI-4 PF05278.12 KER32650.1 - 9.7 5.7 15.6 0.4 10.2 6.5 2.2 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Drc1-Sld2 PF11719.8 KER32651.1 - 0.12 11.8 9.5 0.14 11.7 0.1 3.7 3 2 1 4 4 4 0 DNA replication and checkpoint protein Rab_bind PF16704.5 KER32651.1 - 0.18 11.8 1.0 17 5.6 0.0 3.6 3 0 0 3 3 3 0 Rab binding domain Occludin_ELL PF07303.13 KER32651.1 - 0.23 12.2 8.3 50 4.7 2.4 4.0 4 0 0 4 4 4 0 Occludin homology domain ATG16 PF08614.11 KER32651.1 - 0.26 11.5 7.6 0.079 13.2 2.6 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KER32651.1 - 0.67 10.0 2.7 1.3 9.0 0.2 2.5 3 0 0 3 3 3 0 Laminin Domain II Cnn_1N PF07989.11 KER32651.1 - 3.6 7.8 5.3 5.7 7.2 0.1 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Ion_trans_2 PF07885.16 KER32653.1 - 6.9e-20 70.8 11.8 1.5e-11 44.1 4.7 2.2 2 0 0 2 2 2 2 Ion channel DUF4448 PF14610.6 KER32653.1 - 0.017 14.9 0.4 0.03 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3377 PF11857.8 KER32653.1 - 0.062 13.2 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) UBX PF00789.20 KER32654.1 - 2.1e-07 31.0 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 UBX domain ERM PF00769.19 KER32654.1 - 0.0013 18.7 22.3 0.0019 18.1 22.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C2H2 PF00096.26 KER32657.1 - 3.5e-10 39.8 32.9 0.00037 20.8 6.0 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER32657.1 - 6.4e-07 29.7 30.2 0.00039 21.0 4.9 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER32657.1 - 0.0006 20.1 3.4 0.0006 20.1 3.4 4.6 4 0 0 4 4 4 2 Zinc-finger double domain SIR2 PF02146.17 KER32657.1 - 0.037 14.0 3.1 0.052 13.5 1.7 1.9 2 0 0 2 2 2 0 Sir2 family zf-C2H2_2 PF12756.7 KER32657.1 - 0.037 14.4 0.5 0.037 14.4 0.5 2.9 1 1 1 2 2 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KER32657.1 - 0.053 13.5 25.8 1.2 9.2 7.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger XPA_N PF01286.18 KER32657.1 - 0.33 11.0 8.1 0.41 10.7 0.2 3.0 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_8 PF15909.5 KER32657.1 - 0.4 11.0 16.0 2.5 8.5 1.0 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon T5orf172 PF10544.9 KER32657.1 - 0.51 10.9 5.9 0.31 11.6 0.3 2.5 2 0 0 2 2 2 0 T5orf172 domain zf-met PF12874.7 KER32657.1 - 1.7 9.1 13.4 3.3 8.2 2.9 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER32657.1 - 4.2 7.8 15.1 4.3 7.7 0.8 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KER32657.1 - 4.4 7.7 19.3 2 8.7 12.3 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RVT_1 PF00078.27 KER32658.1 - 6.2e-41 140.3 0.0 7.2e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_5 PF13854.6 KER32659.1 - 8.4e-35 118.2 0.2 4.9e-06 26.4 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KER32659.1 - 1.3e-28 98.7 4.3 2e-06 27.9 0.0 7.5 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KER32659.1 - 1.8e-23 82.3 2.7 0.00018 21.4 0.0 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KER32659.1 - 4.4e-21 74.4 0.4 0.0079 16.5 0.0 6.9 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KER32659.1 - 3.6e-16 58.5 0.3 0.0006 19.4 0.1 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KER32659.1 - 1.6e-15 56.4 0.7 0.0017 18.2 0.0 6.4 6 1 0 6 6 6 4 Kelch motif fn3 PF00041.21 KER32659.1 - 7.2e-10 39.1 1.3 0.011 16.1 0.0 4.4 4 0 0 4 4 4 2 Fibronectin type III domain Mononeg_mRNAcap PF14318.6 KER32659.1 - 0.23 10.7 1.4 0.44 9.7 1.4 1.4 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Vps39_1 PF10366.9 KER32660.1 - 1.1e-20 73.9 1.1 1.1e-20 73.9 1.1 3.5 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 KER32660.1 - 2.8e-12 46.8 0.0 5e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 CNH domain Clathrin PF00637.20 KER32660.1 - 3e-06 27.1 0.2 0.0013 18.7 0.2 3.9 4 0 0 4 4 4 1 Region in Clathrin and VPS AlkA_N PF06029.11 KER32660.1 - 0.005 17.1 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AlkA N-terminal domain Hira PF07569.11 KER32660.1 - 0.17 11.6 0.3 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split SAM_2 PF07647.17 KER32662.1 - 1.6e-07 31.3 0.2 0.0015 18.6 0.0 3.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KER32662.1 - 9.6e-07 29.2 0.1 0.21 12.1 0.0 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KER32662.1 - 0.0066 16.4 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain MID_MedPIWI PF18296.1 KER32662.1 - 0.011 15.5 1.9 0.011 15.5 1.9 2.9 2 1 0 2 2 2 0 MID domain of medPIWI ESP PF16590.5 KER32663.1 - 0.055 13.7 0.1 15 6.0 0.0 2.8 2 0 0 2 2 2 0 Exocrine gland-secreting peptide DUF5488 PF17590.2 KER32663.1 - 0.069 12.9 0.2 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5488) ProRS-C_2 PF09181.10 KER32663.1 - 0.11 12.7 0.1 25 5.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Lustrin_cystein PF14625.6 KER32663.1 - 0.54 10.7 2.8 33 4.9 0.2 3.0 4 0 0 4 4 4 0 Lustrin, cysteine-rich repeated domain CPSF_A PF03178.15 KER32665.1 - 5.4e-62 210.0 0.0 1.2e-61 208.8 0.0 1.6 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KER32665.1 - 6.8e-21 74.5 0.1 2.1e-13 49.7 0.0 3.2 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term RVT_1 PF00078.27 KER32665.1 - 7.5e-16 58.3 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Endosulfine PF04667.17 KER32667.1 - 7.4e-12 45.2 0.1 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region CAF1 PF04857.20 KER32670.1 - 3.7e-24 85.5 1.8 2.6e-12 46.5 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease DUF2152 PF10222.9 KER32671.1 - 1.8e-79 267.8 0.1 9.8e-51 172.8 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Kelch_1 PF01344.25 KER32674.1 - 1.6e-55 184.4 7.0 9.9e-13 47.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KER32674.1 - 7.2e-31 105.4 2.0 6.4e-07 29.4 0.0 6.5 3 2 3 6 6 6 5 Kelch motif BTB PF00651.31 KER32674.1 - 3.7e-24 85.1 0.0 9.9e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KER32674.1 - 1.7e-23 82.7 0.1 3.8e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 KER32674.1 - 8.7e-18 63.5 2.4 1.5e-05 24.7 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KER32674.1 - 7.9e-16 57.8 3.0 0.015 15.3 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KER32674.1 - 9.5e-13 48.1 3.7 0.00053 20.2 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KER32674.1 - 0.087 12.8 0.0 8 6.6 0.0 3.6 3 0 0 3 3 3 0 Kelch motif DUF3342 PF11822.8 KER32674.1 - 0.13 12.4 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) MRP-L51 PF10244.9 KER32676.1 - 2.8e-28 98.0 0.3 4.9e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit zf-H2C2_2 PF13465.6 KER32677.1 - 1.1e-07 32.0 5.2 8.4e-06 26.0 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER32677.1 - 2.5e-05 24.5 13.0 0.037 14.5 6.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER32677.1 - 0.0078 17.0 9.0 2.5 9.2 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER32677.1 - 0.032 14.5 0.3 0.032 14.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KER32677.1 - 0.13 12.3 0.6 0.61 10.1 0.6 2.2 1 0 0 1 1 1 0 BED zinc finger zf-DBF PF07535.12 KER32677.1 - 0.15 12.2 0.4 0.34 11.0 0.4 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_6 PF13912.6 KER32677.1 - 1.4 9.0 4.6 1.2 9.2 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 KER32677.1 - 7.5 6.8 9.1 1.1e+02 3.0 9.1 2.5 1 1 0 1 1 1 0 FYVE zinc finger Aminotran_1_2 PF00155.21 KER32680.1 - 3.5e-72 243.6 0.1 4e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Asp_protease PF09668.10 KER32684.1 - 3.7e-52 175.3 0.0 5.4e-52 174.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KER32684.1 - 1.1e-18 67.6 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER32684.1 - 1.5e-08 35.2 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KER32684.1 - 3.5e-06 26.8 0.0 9.1e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.23 KER32684.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.20 KER32684.1 - 0.00068 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease CysA_C_terminal PF17850.1 KER32684.1 - 0.085 13.4 0.3 0.35 11.5 0.0 2.2 3 0 0 3 3 3 0 CysA C-terminal regulatory domain DUF1194 PF06707.11 KER32686.1 - 0.21 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) NUDIX PF00293.28 KER32688.1 - 2.6e-10 40.5 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 KER32689.1 - 1.4e-07 32.1 10.6 0.27 12.2 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER32689.1 - 0.001 19.3 0.0 1.8 8.9 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DDHD PF02862.17 KER32691.1 - 1.3e-47 162.9 0.1 1.3e-47 162.9 0.1 1.8 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 KER32691.1 - 0.0002 21.9 0.6 0.059 14.0 0.3 2.7 1 1 1 2 2 2 2 WWE domain ABC_membrane PF00664.23 KER32692.1 - 2.4e-50 171.7 11.7 2.2e-49 168.6 11.7 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KER32692.1 - 9.5e-15 55.3 0.0 1.8e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KER32692.1 - 0.00013 22.5 0.0 0.00063 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KER32692.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KER32692.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KER32692.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF3487 PF11990.8 KER32692.1 - 0.052 13.4 1.9 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) AAA_21 PF13304.6 KER32692.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KER32692.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ABC_membrane PF00664.23 KER32693.1 - 3.2e-40 138.5 3.6 4.6e-38 131.4 0.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KER32693.1 - 2.4e-33 115.6 0.0 5.1e-33 114.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KER32693.1 - 4.4e-07 29.6 0.1 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KER32693.1 - 5.7e-06 26.8 0.2 2e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KER32693.1 - 0.0012 18.6 0.0 0.064 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KER32693.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KER32693.1 - 0.0017 18.6 0.1 0.034 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KER32693.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase G-alpha PF00503.20 KER32693.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KER32693.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3987 PF13148.6 KER32693.1 - 0.036 13.1 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 KER32693.1 - 0.041 13.4 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KER32693.1 - 0.048 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KER32693.1 - 0.065 12.8 1.1 0.53 9.8 0.4 2.5 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KER32693.1 - 0.095 12.9 0.5 0.75 10.1 0.5 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KER32693.1 - 0.098 12.7 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KER32693.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KER32693.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KER32693.1 - 0.12 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 KER32693.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KER32693.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KER32693.1 - 0.15 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.20 KER32693.1 - 0.16 11.8 0.1 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Hyd_WA PF06462.12 KER32694.1 - 0.0001 22.2 0.1 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 Propeller ETX_MTX2 PF03318.13 KER32695.1 - 0.00012 22.0 1.4 0.00067 19.5 1.4 2.0 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 P33MONOX PF15302.6 KER32695.1 - 0.044 13.5 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Band_7 PF01145.25 KER32696.1 - 1.3e-36 126.2 3.6 4.3e-32 111.6 0.3 2.2 2 0 0 2 2 2 2 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER32696.1 - 1.2e-06 28.4 0.1 0.00046 20.0 0.0 2.2 2 0 0 2 2 2 2 SPFH domain-Band 7 family GP68 PF17469.2 KER32696.1 - 0.00021 21.6 3.8 0.37 11.2 0.3 2.5 2 0 0 2 2 2 2 Phage protein Gp68 Cas6 PF09559.10 KER32696.1 - 0.0066 16.4 1.5 0.5 10.3 0.2 2.3 2 0 0 2 2 2 1 Cas6 Crispr DUF1471 PF07338.13 KER32696.1 - 0.017 15.1 5.5 1.8 8.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) MIase PF02426.16 KER32696.1 - 0.019 15.1 3.0 5 7.4 0.2 2.7 2 0 0 2 2 2 0 Muconolactone delta-isomerase DUF22 PF01629.16 KER32696.1 - 0.022 14.4 0.0 6.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF22 GatB_N PF02934.15 KER32696.1 - 0.048 13.0 0.2 6.7 6.0 0.0 2.2 2 0 0 2 2 2 0 GatB/GatE catalytic domain BB_PF PF18063.1 KER32696.1 - 0.14 11.7 0.0 20 4.7 0.0 2.2 2 0 0 2 2 2 0 Beta barrel Pore-forming domain Spiralin PF05215.13 KER32696.1 - 0.25 10.7 1.8 13 5.0 0.1 2.9 3 0 0 3 3 3 0 Spiralin DUF5569 PF17729.1 KER32696.1 - 0.84 9.5 3.2 13 5.6 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5569) DctP PF03480.13 KER32696.1 - 1.2 8.4 4.8 12 5.1 0.4 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF4735 PF15882.5 KER32697.1 - 5e-56 190.3 0.0 5.9e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) RIB43A PF05914.12 KER32698.1 - 3.5e-112 374.9 47.9 1.3e-68 231.5 28.3 2.0 1 1 1 2 2 2 2 RIB43A Speriolin_C PF15059.6 KER32698.1 - 0.0066 16.6 0.3 0.021 14.9 0.3 1.8 1 0 0 1 1 1 1 Speriolin C-terminus Poty_PP PF08440.10 KER32699.1 - 0.0038 16.3 0.3 0.33 10.0 0.1 3.0 3 0 0 3 3 3 1 Potyviridae polyprotein Peptidase_C14 PF00656.22 KER32699.1 - 0.0069 16.4 3.0 1.6 8.6 0.1 2.5 2 1 1 3 3 3 2 Caspase domain CAMSAP_CC1 PF17095.5 KER32699.1 - 0.045 13.6 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF3950 PF13132.6 KER32699.1 - 0.095 12.5 0.0 26 4.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Proteasome PF00227.26 KER32700.1 - 1.5e-49 168.1 0.1 1.8e-49 167.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KER32700.1 - 2.6e-05 23.5 0.2 2.6e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Hep_59 PF07052.11 KER32701.1 - 1.2e-29 103.1 1.7 6.6e-29 100.8 0.1 2.6 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Latarcin PF10279.9 KER32701.1 - 0.028 14.8 1.4 4.4 7.8 0.3 2.3 2 0 0 2 2 2 0 Latarcin precursor Ion_trans PF00520.31 KER32702.1 - 5.9e-32 110.8 28.6 4.8e-19 68.5 8.7 2.5 2 0 0 2 2 2 2 Ion transport protein Ank_2 PF12796.7 KER32702.1 - 1.9e-08 34.7 0.1 0.0052 17.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER32702.1 - 1.2e-07 31.9 1.5 0.00037 20.7 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32702.1 - 1.9e-06 27.7 0.8 1.4 9.8 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KER32702.1 - 3.5e-05 24.3 0.0 0.62 10.7 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KER32702.1 - 0.00013 22.3 0.3 0.023 15.1 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF4577 PF15145.6 KER32702.1 - 0.19 11.8 0.5 6.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Ank_2 PF12796.7 KER32703.1 - 1.1e-09 38.7 0.0 2.6e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER32703.1 - 1.2e-09 38.5 0.1 7.1e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER32703.1 - 3.8e-08 33.0 0.1 0.24 12.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KER32703.1 - 1e-07 32.1 0.1 2.7e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KER32703.1 - 1.5e-05 25.2 1.1 0.32 11.5 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat PDH_E1_M PF17831.1 KER32703.1 - 0.057 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain ACT PF01842.25 KER32703.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain Pkinase PF00069.25 KER32704.1 - 7e-57 192.8 0.0 5.9e-56 189.8 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER32704.1 - 4.4e-27 95.0 0.0 1.3e-26 93.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.27 KER32704.1 - 1.8e-20 73.4 0.0 5e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kinase-like PF14531.6 KER32704.1 - 9.6e-06 25.1 1.1 1.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1664 PF07889.12 KER32704.1 - 0.0013 18.8 37.8 0.1 12.6 6.5 5.6 3 2 1 5 5 5 4 Protein of unknown function (DUF1664) Spc7 PF08317.11 KER32704.1 - 0.014 14.3 67.6 0.012 14.6 9.3 4.9 2 1 2 4 4 4 0 Spc7 kinetochore protein TetR_C_24 PF17932.1 KER32704.1 - 0.028 14.7 0.6 8.4 6.7 0.4 3.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 KER32704.1 - 0.032 14.1 0.0 0.032 14.1 0.0 3.0 3 1 0 3 3 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER32704.1 - 0.13 11.3 0.2 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 DUF5595 PF18077.1 KER32704.1 - 0.56 10.3 2.5 15 5.8 1.0 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) Peripla_BP_2 PF01497.18 KER32704.1 - 2.4 7.7 4.5 1.4 8.5 1.1 2.2 2 0 0 2 2 2 0 Periplasmic binding protein TPK_B1_binding PF04265.14 KER32706.1 - 1.7e-18 66.1 0.0 2.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 KER32706.1 - 4.5e-13 49.3 0.1 1e-06 28.8 0.0 2.4 1 1 1 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain AMP-binding PF00501.28 KER32707.1 - 5e-05 22.1 0.0 8.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER32707.1 - 6.6e-05 23.8 0.0 0.00015 22.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Itfg2 PF15907.5 KER32708.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Integrin-alpha FG-GAP repeat-containing protein 2 ACAS_N PF16177.5 KER32708.1 - 1.8e-08 34.1 0.5 3e-08 33.5 0.5 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Transglut_core PF01841.19 KER32709.1 - 1.7e-06 28.4 0.0 3.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily Big_3 PF07523.12 KER32709.1 - 0.041 14.2 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF4606 PF15379.6 KER32711.1 - 0.012 15.8 1.3 0.11 12.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Maf1 PF09174.10 KER32711.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Maf1 regulator Hjc PF01870.18 KER32712.1 - 0.0024 17.8 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Archaeal holliday junction resolvase (hjc) Meis_PKNOX_N PF16493.5 KER32713.1 - 3.9e-34 116.8 1.4 3.9e-25 88.0 0.2 2.3 2 0 0 2 2 2 2 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 KER32713.1 - 4e-20 71.4 4.5 8.6e-20 70.4 0.5 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KER32713.1 - 4.5e-08 32.8 0.2 9.7e-08 31.8 0.2 1.5 1 0 0 1 1 1 1 Homeodomain PI-PLC-C1 PF16670.5 KER32714.1 - 1.7 7.7 3.6 3.6 6.6 0.2 2.4 2 1 1 3 3 3 0 Phosphoinositide phospholipase C, Ca2+-dependent GCP_C_terminal PF04130.13 KER32716.1 - 1.4e-76 257.9 7.6 3.3e-76 256.7 7.6 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KER32716.1 - 2.1e-76 257.5 0.0 4.7e-76 256.3 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Clathrin_bdg PF15045.6 KER32717.1 - 0.0015 18.5 0.0 0.0064 16.5 0.0 2.2 1 1 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Amidase PF01425.21 KER32719.1 - 1.4e-101 340.7 0.0 2e-101 340.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KER32720.1 - 2e-98 330.3 0.0 2.8e-98 329.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Mito_carr PF00153.27 KER32721.1 - 3.8e-47 158.1 3.3 2.4e-16 59.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IIc PF10439.9 KER32721.1 - 0.74 10.0 5.7 13 6.0 0.0 3.3 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide DUF89 PF01937.19 KER32723.1 - 5e-76 255.9 0.0 4.9e-74 249.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 eIF-5_eIF-2B PF01873.17 KER32724.1 - 1.3e-40 137.9 0.4 2.4e-40 137.0 0.4 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KER32724.1 - 1.6e-20 73.0 0.7 1.6e-20 73.0 0.7 1.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Elf1 PF05129.13 KER32724.1 - 0.13 12.3 0.2 0.41 10.7 0.2 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SpoIIIAH PF12685.7 KER32724.1 - 0.18 11.6 7.7 0.055 13.3 1.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein eIF-5_eIF-2B PF01873.17 KER32725.1 - 1.3e-40 137.9 0.4 2.4e-40 137.0 0.4 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KER32725.1 - 1.6e-20 73.0 0.7 1.6e-20 73.0 0.7 1.8 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Elf1 PF05129.13 KER32725.1 - 0.13 12.3 0.2 0.41 10.7 0.2 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SpoIIIAH PF12685.7 KER32725.1 - 0.18 11.6 7.7 0.055 13.3 1.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein LsmAD PF06741.13 KER32726.1 - 3.5e-12 46.7 0.0 6.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.15 KER32726.1 - 0.035 13.8 0.8 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF2475 PF10629.9 KER32727.1 - 3.8e-20 71.9 10.8 8.6e-08 32.3 0.6 4.5 4 1 0 4 4 4 4 Protein of unknown function (DUF2475) Coq4 PF05019.13 KER32728.1 - 1.1e-62 211.3 0.0 1.5e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 RabGAP-TBC PF00566.18 KER32730.1 - 3.8e-45 154.2 0.0 5.9e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PS_Dcarbxylase PF02666.15 KER32731.1 - 1.7e-56 190.9 0.0 2.1e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Proteasome PF00227.26 KER32732.1 - 4.2e-16 59.0 0.0 5.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Thymidylate_kin PF02223.17 KER32733.1 - 2.9e-31 108.6 0.0 5.1e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KER32733.1 - 0.038 14.2 0.2 0.1 12.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KER32733.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nuc_sug_transp PF04142.15 KER32734.1 - 7.5e-101 337.4 17.7 4.6e-74 249.4 11.1 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 KER32734.1 - 0.0012 18.2 9.7 0.0034 16.6 9.7 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KER32734.1 - 0.0069 16.6 29.0 0.06 13.5 15.1 2.9 3 1 0 3 3 3 2 EamA-like transporter family Arm PF00514.23 KER32735.1 - 1.3e-22 79.1 20.7 7.4e-05 22.7 0.2 8.7 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KER32735.1 - 8.8e-13 47.3 6.1 0.12 12.7 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 KER32735.1 - 1.4e-10 41.5 6.6 0.0078 16.3 0.1 4.5 2 1 3 5 5 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KER32735.1 - 3.3e-09 37.0 9.3 0.032 14.6 0.2 5.4 3 1 3 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 KER32735.1 - 2e-06 28.2 12.5 0.37 11.4 0.1 6.4 3 2 4 7 7 7 3 HEAT-like repeat Atx10homo_assoc PF09759.9 KER32735.1 - 0.00046 20.2 1.4 3.8 7.6 0.1 4.6 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain CHASE6_C PF17150.4 KER32735.1 - 0.00053 20.6 5.5 3.2 8.5 0.0 6.1 6 2 0 6 6 6 1 C-terminal domain of two-partite extracellular sensor domain CLASP_N PF12348.8 KER32735.1 - 0.00078 19.1 3.7 0.17 11.4 0.1 3.0 3 0 0 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 KER32735.1 - 0.002 17.7 4.1 0.6 9.5 0.1 3.2 1 1 1 3 3 3 2 Armadillo-like Proteasom_PSMB PF10508.9 KER32735.1 - 0.0022 16.6 14.6 0.048 12.2 5.0 3.2 2 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit NopRA1 PF16201.5 KER32735.1 - 0.0052 16.4 0.7 1.9 8.0 0.0 3.6 3 1 1 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KER32735.1 - 0.0062 16.8 1.7 8.7 6.7 0.0 4.4 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Rcd1 PF04078.13 KER32735.1 - 0.0063 15.8 3.6 0.034 13.4 1.0 3.1 3 1 1 4 4 4 1 Cell differentiation family, Rcd1-like DUF3361 PF11841.8 KER32735.1 - 0.011 15.7 7.1 0.067 13.1 2.4 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) DNA_alkylation PF08713.11 KER32735.1 - 0.027 14.2 0.9 8.2 6.1 0.0 3.5 3 1 1 4 4 4 0 DNA alkylation repair enzyme COMMD1_N PF17221.3 KER32735.1 - 0.04 14.2 1.5 0.4 11.0 0.2 2.9 3 0 0 3 3 2 0 COMMD1 N-terminal domain HEAT_PBS PF03130.16 KER32735.1 - 0.044 14.5 6.9 0.31 11.8 0.0 4.6 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat BtpA PF03437.15 KER32735.1 - 0.061 12.8 1.9 0.13 11.7 1.9 1.5 1 0 0 1 1 1 0 BtpA family DUF2046 PF09755.9 KER32735.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) API5 PF05918.11 KER32735.1 - 0.17 10.7 4.5 0.28 9.9 4.0 1.6 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Rgp1 PF08737.10 KER32736.1 - 7.7e-15 55.0 0.0 1e-08 34.8 0.0 2.4 2 1 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 KER32736.1 - 0.063 13.3 0.0 0.85 9.7 0.0 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain RVT_1 PF00078.27 KER32738.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Reprolysin_2 PF13574.6 KER32741.1 - 1e-17 64.7 0.5 1.5e-17 64.1 0.0 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KER32741.1 - 6.8e-14 52.5 0.1 6.8e-14 52.5 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Disintegrin PF00200.23 KER32741.1 - 6.1e-12 46.2 21.5 6.1e-12 46.2 21.5 2.5 2 0 0 2 2 2 1 Disintegrin Reprolysin_3 PF13582.6 KER32741.1 - 7.9e-10 39.3 0.0 1.2e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KER32741.1 - 3.1e-05 23.7 0.5 6.2e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KER32741.1 - 0.00021 21.3 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 KER32741.1 - 0.084 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Matrixin SAM_4 PF18017.1 KER32743.1 - 9.6e-20 70.3 0.1 1.6e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 KER32743.1 - 7.9e-08 32.3 18.1 1.6e-07 31.3 2.3 4.2 2 1 1 3 3 3 2 Family of unknown function (DUF5577) SAM_2 PF07647.17 KER32743.1 - 1.4e-07 31.5 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KER32743.1 - 0.00041 20.7 0.0 0.00066 20.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5614 PF18474.1 KER32743.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5614) Myb_DNA-binding PF00249.31 KER32745.1 - 0.081 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain 7tm_1 PF00001.21 KER32746.1 - 0.00027 20.4 3.1 0.00052 19.4 0.3 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 KER32747.1 - 3.1e-18 66.0 35.4 4.1e-13 49.3 10.7 3.9 4 0 0 4 4 4 2 7 transmembrane receptor (rhodopsin family) Glycoprotein_G PF00802.19 KER32747.1 - 0.089 12.2 2.5 6.5 6.0 0.2 2.3 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G DUF5510 PF17629.2 KER32747.1 - 7.1 6.7 18.2 15 5.6 5.1 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Ctr PF04145.15 KER32747.1 - 9.4 6.8 15.0 3.6 8.2 1.4 2.9 3 0 0 3 3 3 0 Ctr copper transporter family DUF296 PF03479.15 KER32748.1 - 1.8e-25 89.4 2.1 3e-25 88.6 2.1 1.4 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Zip PF02535.22 KER32752.1 - 0.15 11.3 1.0 0.15 11.2 1.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KER32752.1 - 0.53 8.3 41.5 0.59 8.2 41.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KER32752.1 - 0.72 8.1 21.5 0.74 8.0 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2796 PF10986.8 KER32752.1 - 0.73 9.8 7.5 0.96 9.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Nop14 PF04147.12 KER32752.1 - 0.98 7.5 28.7 1.1 7.4 28.7 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KER32752.1 - 3.6 6.9 21.8 4.1 6.7 21.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 KER32752.1 - 4.9 5.5 27.5 5.5 5.3 27.5 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KER32752.1 - 6.3 6.1 28.3 6.4 6.1 28.3 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KER32752.1 - 7.1 5.0 27.1 7.4 5.0 27.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SpoIIIAH PF12685.7 KER32752.1 - 7.2 6.4 8.6 7.7 6.3 8.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein LIN52 PF10044.9 KER32754.1 - 1.4e-20 73.8 1.6 1e-18 67.8 1.6 2.0 1 1 0 1 1 1 1 Retinal tissue protein TT1725 PF18324.1 KER32755.1 - 0.039 14.0 0.8 0.18 11.9 0.8 2.2 1 0 0 1 1 1 0 Hypothetical protein TT1725 DUF1741 PF08427.10 KER32755.1 - 0.049 13.3 6.9 0.13 11.9 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Med5 PF08689.10 KER32755.1 - 3.6 5.3 7.8 6.2 4.5 7.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit Med5 Thioredoxin PF00085.20 KER32756.1 - 7.9e-29 99.7 0.1 9.3e-29 99.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KER32756.1 - 3.2e-10 40.4 0.0 6e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KER32756.1 - 1.3e-07 31.9 0.0 0.00073 19.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KER32756.1 - 1.4e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KER32756.1 - 0.0013 18.2 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KER32756.1 - 0.0027 17.5 0.1 0.0032 17.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KER32756.1 - 0.0034 17.3 0.0 0.0057 16.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.14 KER32756.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.11 KER32756.1 - 0.067 13.2 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 KER32756.1 - 0.088 12.4 0.0 0.41 10.3 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 KER32756.1 - 0.095 12.4 0.4 0.52 10.0 0.1 1.9 1 1 1 2 2 2 0 Redoxin DUF2605 PF10792.9 KER32756.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Na_Ca_ex PF01699.24 KER32757.1 - 1.2e-48 164.9 39.3 8.3e-26 90.8 19.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein rve PF00665.26 KER32757.1 - 1.3e-24 86.7 0.0 2.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KER32757.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CytochromB561_N PF09786.9 KER32760.1 - 3.2e-55 188.2 8.7 3.9e-54 184.6 8.7 2.1 1 1 0 1 1 1 1 Cytochrome B561, N terminal Aldedh PF00171.22 KER32762.1 - 0.018 13.6 0.0 0.066 11.7 0.0 1.9 2 1 0 2 2 2 0 Aldehyde dehydrogenase family Ndr PF03096.14 KER32765.1 - 5.3e-38 130.3 0.0 4.3e-37 127.3 0.0 2.2 1 1 0 1 1 1 1 Ndr family Cpn60_TCP1 PF00118.24 KER32766.1 - 2.8e-05 23.0 0.0 2.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP70 PF00012.20 KER32768.1 - 2.4e-144 481.8 0.3 2.9e-144 481.5 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER32768.1 - 8.6e-19 67.5 0.6 4.6e-18 65.1 0.3 1.9 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 KER32768.1 - 0.0064 15.8 0.4 0.074 12.3 0.0 2.1 1 1 1 2 2 2 2 StbA protein Hydantoinase_A PF01968.18 KER32768.1 - 0.012 14.8 0.2 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 KER32768.1 - 0.33 11.4 1.3 29 5.1 0.1 2.9 3 1 0 3 3 3 0 Cell division protein FtsA ATP_bind_1 PF03029.17 KER32769.1 - 4.4e-78 262.4 0.2 9.8e-78 261.3 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsJ PF01728.19 KER32769.1 - 1.8e-40 139.0 0.0 2.8e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase YdjM PF04307.14 KER32769.1 - 0.0022 17.3 6.3 0.0048 16.2 6.3 1.5 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase AAA_18 PF13238.6 KER32769.1 - 0.022 15.3 0.0 0.08 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KER32769.1 - 0.025 13.9 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 KER32769.1 - 0.046 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 KER32769.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KER32769.1 - 0.15 12.3 0.0 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KER32769.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KER32769.1 - 0.19 12.1 0.0 0.65 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain PHD PF00628.29 KER32770.1 - 0.00039 20.3 6.2 0.001 18.9 6.2 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KER32770.1 - 0.17 11.8 2.9 0.42 10.6 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF410 PF04190.13 KER32771.1 - 1.3e-60 205.4 0.1 1.6e-60 205.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SUFU_C PF12470.8 KER32772.1 - 8.4e-41 140.3 0.0 1e-37 130.2 0.0 2.3 2 0 0 2 2 2 2 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.13 KER32772.1 - 2.6e-39 134.9 0.0 5.9e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 Suppressor of fused protein (SUFU) RAWUL PF16207.5 KER32773.1 - 4.1e-07 30.6 0.4 5.7e-07 30.1 0.4 1.2 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 KER32774.1 - 1.2e-14 53.9 9.0 2.3e-14 52.9 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KER32774.1 - 4.6e-10 39.2 9.1 9.2e-10 38.2 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER32774.1 - 9.8e-09 35.4 7.8 9.8e-09 35.4 7.8 1.9 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER32774.1 - 2.2e-07 30.6 7.2 3.4e-07 30.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pas_Saposin PF09016.10 KER32774.1 - 1.2e-06 28.7 0.3 0.064 13.6 0.0 2.3 2 0 0 2 2 2 2 Pas factor saposin fold zf-RING_UBOX PF13445.6 KER32774.1 - 7e-06 26.0 6.9 1.7e-05 24.8 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KER32774.1 - 1.1e-05 25.3 7.1 2e-05 24.4 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KER32774.1 - 8.6e-05 22.3 4.3 0.00015 21.5 4.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KER32774.1 - 0.00013 22.0 7.3 0.00024 21.2 7.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KER32774.1 - 0.00023 21.0 3.6 0.00045 20.0 3.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KER32774.1 - 0.0012 18.6 7.6 0.0033 17.2 7.6 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KER32774.1 - 0.0015 18.7 7.9 0.013 15.7 8.0 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KER32774.1 - 0.0088 15.9 7.8 0.51 10.2 8.4 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 GLYCAM-1 PF05242.11 KER32774.1 - 0.042 14.0 0.1 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Phage_int_SAM_1 PF02899.17 KER32774.1 - 0.052 13.9 2.9 6.5 7.1 0.2 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF5403 PF17395.2 KER32774.1 - 0.059 13.7 0.3 5 7.5 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5403) zf-C4_Topoisom PF01396.19 KER32774.1 - 0.098 12.4 0.3 0.098 12.4 0.3 1.7 2 0 0 2 2 1 0 Topoisomerase DNA binding C4 zinc finger zf-C3HC4_5 PF17121.5 KER32774.1 - 0.15 12.0 8.2 0.63 10.0 8.2 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER32774.1 - 0.17 12.0 2.7 0.37 10.9 2.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 KER32774.1 - 0.59 10.3 5.2 1.7 8.9 5.2 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger Corazonin PF17308.2 KER32774.1 - 0.92 9.9 8.4 5.3 7.4 1.0 2.5 1 1 2 3 3 3 0 Pro-corazonin zf-MIZ PF02891.20 KER32774.1 - 1.6 8.6 5.7 3.8 7.3 5.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Histone PF00125.24 KER32775.1 - 1.7e-25 89.9 0.0 1.9e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LRR_6 PF13516.6 KER32776.1 - 0.013 15.5 0.7 8.8 6.7 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KER32776.1 - 0.069 12.9 0.1 0.069 12.9 0.1 3.1 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 KER32776.1 - 1.3 9.5 6.2 22 5.6 0.3 3.2 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER32776.1 - 1.9 9.4 7.9 38 5.4 0.5 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat Myb_DNA-bind_4 PF13837.6 KER32777.1 - 6.9e-09 36.0 1.3 1.3e-08 35.1 1.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KER32777.1 - 0.0003 21.0 0.4 0.00065 20.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.6 KER32777.1 - 0.0093 16.2 0.8 0.019 15.2 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KER32777.1 - 0.038 14.2 1.5 0.065 13.4 1.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KER32777.1 - 0.073 14.1 2.3 0.17 12.9 2.3 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KER32777.1 - 0.079 13.1 2.1 0.26 11.4 2.1 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.29 KER32780.1 - 1.8e-42 145.1 0.0 3.3e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER32780.1 - 1e-27 96.7 0.0 2.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER32780.1 - 7.3e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KER32780.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Bromodomain PF00439.25 KER32783.1 - 2.4e-18 65.9 0.0 8.1e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KER32783.1 - 1.9e-16 59.7 20.4 3.9e-11 42.7 5.4 3.1 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 KER32783.1 - 9.6e-13 48.5 0.1 9.1e-05 22.9 0.0 3.2 2 0 0 2 2 2 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MBD PF01429.19 KER32783.1 - 1.2e-08 34.6 0.0 3.8e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyl-CpG binding domain DDT PF02791.17 KER32783.1 - 5.7e-06 26.5 1.8 1.3e-05 25.4 1.8 1.7 1 0 0 1 1 1 1 DDT domain PHD_2 PF13831.6 KER32783.1 - 0.1 12.2 12.9 0.34 10.5 4.4 2.8 2 0 0 2 2 2 0 PHD-finger AT_hook PF02178.19 KER32783.1 - 0.21 11.6 2.9 1 9.5 2.9 2.3 1 0 0 1 1 1 0 AT hook motif C1_1 PF00130.22 KER32783.1 - 4.9 7.1 15.1 14 5.7 2.7 3.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DCX PF03607.17 KER32785.1 - 5.2e-06 26.5 0.2 2.1 8.5 0.0 4.4 4 0 0 4 4 4 3 Doublecortin Ricin_B_lectin PF00652.22 KER32785.1 - 1.2e-05 25.6 1.2 0.14 12.4 0.0 3.6 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain DUF1043 PF06295.12 KER32785.1 - 0.36 10.8 6.0 0.37 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) TMF_TATA_bd PF12325.8 KER32785.1 - 2.9 8.1 6.9 3 8.1 2.3 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Mod_r PF07200.13 KER32785.1 - 3.5 7.7 7.8 1.6 8.9 3.5 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DCX PF03607.17 KER32786.1 - 1.2e-07 31.8 0.0 0.0077 16.3 0.0 2.7 2 0 0 2 2 2 2 Doublecortin GrpE PF01025.19 KER32787.1 - 5.5e-45 153.0 0.3 7.2e-45 152.6 0.3 1.1 1 0 0 1 1 1 1 GrpE SKA2 PF16740.5 KER32787.1 - 0.0082 15.9 1.2 0.016 14.9 1.2 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 KER32787.1 - 0.017 15.6 1.0 0.027 15.0 1.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 KER32787.1 - 0.024 15.0 2.2 0.044 14.1 1.5 1.8 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 KER32787.1 - 0.028 14.1 2.5 0.042 13.6 2.5 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4472 PF14739.6 KER32787.1 - 0.049 14.4 1.7 0.097 13.4 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) MutS_II PF05188.17 KER32787.1 - 0.058 13.7 0.3 0.1 12.9 0.3 1.4 1 0 0 1 1 1 0 MutS domain II V-ATPase_G_2 PF16999.5 KER32787.1 - 0.11 12.9 1.6 0.19 12.2 1.6 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit BcrAD_BadFG PF01869.20 KER32788.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family BcrAD_BadFG PF01869.20 KER32791.1 - 2.8e-16 59.8 0.2 3.3e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Ras PF00071.22 KER32792.1 - 4.5e-18 65.4 0.0 9e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER32792.1 - 3.1e-08 33.8 0.0 7.9e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KER32792.1 - 3.9e-06 26.0 0.3 1.2e-05 24.5 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KER32792.1 - 8.9e-06 25.0 0.4 2.4e-05 23.6 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KER32792.1 - 2.2e-05 24.0 0.1 6.8e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KER32792.1 - 5.3e-05 23.6 1.0 0.00015 22.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Arf PF00025.21 KER32792.1 - 7.6e-05 22.2 0.0 7.6e-05 22.2 0.0 2.1 3 0 0 3 3 2 1 ADP-ribosylation factor family EF-hand_8 PF13833.6 KER32792.1 - 0.00021 21.1 0.3 0.00069 19.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair Uso1_p115_C PF04871.13 KER32792.1 - 0.013 15.8 15.7 0.033 14.6 15.7 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TspO_MBR PF03073.15 KER32792.1 - 0.04 14.0 5.1 0.08 13.0 4.7 1.6 1 1 0 1 1 1 0 TspO/MBR family DUF2573 PF10835.8 KER32792.1 - 0.041 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) ABC_tran PF00005.27 KER32792.1 - 0.051 14.1 7.3 0.61 10.6 0.0 4.3 4 1 0 4 4 4 0 ABC transporter CorA PF01544.18 KER32792.1 - 0.094 12.0 10.3 0.18 11.1 10.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cas_DxTHG PF09455.10 KER32792.1 - 0.75 9.3 6.4 1.2 8.6 6.4 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family HALZ PF02183.18 KER32792.1 - 2.3 8.5 5.1 11 6.3 0.7 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper PikAIV_N PF18605.1 KER32792.1 - 9 6.0 12.8 6.6 6.4 0.1 2.9 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Exonuc_VII_L PF02601.15 KER32792.1 - 9.2 5.7 13.5 16 4.9 13.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rootletin PF15035.6 KER32794.1 - 0.00097 19.2 1.3 0.00099 19.2 1.3 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DHR-2 PF06920.13 KER32794.1 - 0.0029 16.3 1.4 0.0035 16.1 1.4 1.1 1 0 0 1 1 1 1 Dock homology region 2 Nup54 PF13874.6 KER32794.1 - 0.0048 17.0 2.1 0.0092 16.1 2.1 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF3552 PF12072.8 KER32794.1 - 0.019 14.4 5.2 0.028 13.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 KER32794.1 - 0.038 14.0 0.5 0.048 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4709 PF15821.5 KER32794.1 - 0.049 13.9 2.7 0.072 13.4 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) P4Ha_N PF08336.11 KER32794.1 - 0.051 13.6 3.9 0.6 10.1 3.4 2.1 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1917 PF08939.10 KER32794.1 - 0.055 13.4 2.0 0.067 13.1 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) H-kinase_dim PF02895.14 KER32794.1 - 0.12 12.8 3.3 0.19 12.1 3.3 1.4 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain TMPIT PF07851.13 KER32794.1 - 0.16 11.2 4.3 0.23 10.7 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein Takusan PF04822.13 KER32794.1 - 0.25 11.2 7.4 6.5 6.7 7.1 2.4 1 1 0 1 1 1 0 Takusan LPP PF04728.13 KER32794.1 - 0.42 11.0 4.0 3.4 8.1 0.5 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF4404 PF14357.6 KER32794.1 - 0.99 10.1 6.2 1.9 9.2 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) UVR PF02151.19 KER32794.1 - 1.5 8.6 6.2 0.65 9.8 2.2 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif TMF_DNA_bd PF12329.8 KER32794.1 - 7.2 6.7 12.3 0.95 9.5 6.1 1.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding NCD2 PF04905.13 KER32795.1 - 6.1e-23 81.1 0.0 1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) TPR_2 PF07719.17 KER32796.1 - 4.2e-34 113.9 16.4 7.8e-06 25.6 0.2 10.1 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 KER32796.1 - 2.2e-31 106.4 21.4 5.1e-06 26.1 0.1 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KER32796.1 - 2.4e-26 91.8 12.1 2.1e-07 31.1 0.6 7.7 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KER32796.1 - 8.5e-25 84.9 8.9 0.0064 16.4 0.0 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KER32796.1 - 2.1e-24 85.9 0.0 9.7e-10 38.9 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER32796.1 - 5.3e-21 74.9 0.3 7.6e-05 23.1 0.0 5.5 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER32796.1 - 9.3e-21 72.3 26.3 0.018 15.2 0.1 10.9 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 KER32796.1 - 7.1e-20 70.3 15.6 0.0019 18.7 0.0 10.5 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KER32796.1 - 3e-17 61.8 1.3 0.0046 17.7 0.0 8.8 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KER32796.1 - 4.5e-17 61.5 5.6 7.6e-08 31.9 0.1 6.0 5 1 1 6 6 6 3 TPR repeat ANAPC3 PF12895.7 KER32796.1 - 1.5e-12 47.5 12.9 1.3e-05 25.4 1.5 5.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KER32796.1 - 2.5e-11 43.5 0.0 0.0035 17.5 0.0 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KER32796.1 - 6.4e-09 35.4 12.1 0.1 12.5 0.2 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_21 PF09976.9 KER32796.1 - 4.5e-05 23.2 0.1 0.14 11.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KER32796.1 - 0.00041 20.4 3.4 44 4.2 0.0 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 KER32796.1 - 0.0018 17.7 1.8 0.59 9.4 0.0 4.2 3 2 0 4 4 4 1 MalT-like TPR region TPR_3 PF07720.12 KER32796.1 - 0.011 15.7 14.8 3.4 7.8 0.2 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3808 PF10300.9 KER32796.1 - 0.016 14.0 3.3 0.13 10.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) MIT PF04212.18 KER32796.1 - 0.02 14.9 16.9 6.7 6.9 0.0 6.7 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 KER32796.1 - 0.034 14.5 2.5 1.7 9.0 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KER32796.1 - 0.079 12.4 4.5 0.21 10.9 0.0 3.2 4 0 0 4 4 4 0 Coatomer epsilon subunit TPR_17 PF13431.6 KER32796.1 - 0.11 12.9 13.2 7.4 7.2 0.1 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat SPO22 PF08631.10 KER32796.1 - 0.12 11.8 2.8 21 4.4 0.0 3.8 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.17 KER32796.1 - 0.32 11.4 7.3 12 6.3 0.1 5.2 5 2 0 5 5 5 0 Bacterial transcriptional activator domain DUF5344 PF17279.2 KER32796.1 - 0.45 11.1 2.2 14 6.3 0.0 3.7 4 0 0 4 4 3 0 Family of unknown function (DUF5344) Sel1 PF08238.12 KER32796.1 - 1.7 9.4 7.0 89 4.0 0.0 5.1 5 0 0 5 5 4 0 Sel1 repeat RAI16-like PF10257.9 KER32797.1 - 4e-44 151.0 0.1 1.4e-43 149.2 0.1 2.0 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Urocanase PF01175.18 KER32798.1 - 1.5e-79 266.6 0.0 2.2e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 KER32798.1 - 4.7e-79 264.4 0.2 7.7e-79 263.7 0.2 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 KER32798.1 - 2.7e-49 166.1 0.0 7.1e-49 164.7 0.0 1.7 1 0 0 1 1 1 1 Urocanase N-terminal domain Acyl_transf_1 PF00698.21 KER32799.1 - 3.6e-19 69.4 0.4 1.5e-18 67.4 0.4 1.8 1 1 0 1 1 1 1 Acyl transferase domain PTPS PF01242.19 KER32800.1 - 1.1e-32 112.6 0.1 1.4e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF2738 PF10927.8 KER32800.1 - 0.036 13.2 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) tRNA-synt_1 PF00133.22 KER32801.1 - 6.8e-31 107.2 0.0 2.9e-14 52.2 0.1 4.9 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KER32801.1 - 9.9e-22 77.2 0.0 8.6e-17 61.0 0.0 3.2 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KER32801.1 - 0.00078 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 KER32801.1 - 0.11 11.4 0.0 0.88 8.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf-ribbon_3 PF13248.6 KER32801.1 - 0.11 11.9 1.9 1.6 8.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain 7tm_1 PF00001.21 KER32802.1 - 0.0049 16.2 2.9 0.009 15.4 2.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EGF PF00008.27 KER32803.1 - 6.3e-67 221.4 265.2 3.9e-09 36.6 6.8 19.1 18 1 0 18 18 18 15 EGF-like domain hEGF PF12661.7 KER32803.1 - 4e-34 116.1 221.0 5.2e-06 26.9 4.6 20.4 19 2 0 19 19 19 13 Human growth factor-like EGF DSL PF01414.19 KER32803.1 - 1.4e-14 54.0 7.5 1.4e-14 54.0 7.5 13.6 8 3 8 16 16 16 4 Delta serrate ligand EGF_2 PF07974.13 KER32803.1 - 1.3e-10 41.4 302.6 0.0014 19.0 7.0 19.5 19 1 0 19 19 19 14 EGF-like domain EGF_CA PF07645.15 KER32803.1 - 0.0025 18.0 30.8 0.0041 17.3 8.8 19.4 6 3 13 19 19 19 7 Calcium-binding EGF domain EGF_3 PF12947.7 KER32803.1 - 0.014 15.6 4.1 0.014 15.6 4.1 17.5 12 3 4 16 16 16 0 EGF domain FtsJ PF01728.19 KER32804.1 - 1.6e-26 93.5 0.0 3.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Tfb4 PF03850.14 KER32804.1 - 3.2e-18 66.2 0.0 5.6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 G-patch PF01585.23 KER32804.1 - 3e-13 49.4 2.2 5.3e-13 48.6 2.2 1.4 1 0 0 1 1 1 1 G-patch domain WW PF00397.26 KER32804.1 - 2.9e-07 30.4 0.1 6.3e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 WW domain G-patch_2 PF12656.7 KER32804.1 - 1.7e-05 24.8 0.6 3.8e-05 23.7 0.6 1.6 1 0 0 1 1 1 1 G-patch domain HA2 PF04408.23 KER32806.1 - 4.3e-21 75.2 0.0 4.3e-21 75.2 0.0 3.7 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KER32806.1 - 2e-14 53.7 0.0 5.4e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KER32806.1 - 7.6e-14 52.0 0.0 2.9e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DSS1_SEM1 PF05160.13 KER32806.1 - 1.4e-08 34.6 16.2 1.4e-08 34.6 16.2 3.1 3 0 0 3 3 2 1 DSS1/SEM1 family AAA_22 PF13401.6 KER32806.1 - 2.5e-06 27.8 0.0 6.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KER32806.1 - 3.6e-05 24.1 0.1 0.00016 22.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KER32806.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KER32806.1 - 0.00027 20.3 1.1 0.00047 19.5 0.0 2.0 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KER32806.1 - 0.0009 19.1 0.1 0.0023 17.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KER32806.1 - 0.0024 17.0 0.0 0.0063 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KER32806.1 - 0.0066 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 KER32806.1 - 0.037 13.5 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KER32806.1 - 0.04 14.4 2.0 0.073 13.6 0.0 2.5 3 0 0 3 3 1 0 ABC transporter AAA_33 PF13671.6 KER32806.1 - 0.043 14.0 0.1 0.31 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 KER32806.1 - 0.046 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 KER32806.1 - 0.054 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF2947 PF11163.8 KER32806.1 - 0.14 12.1 4.3 0.78 9.6 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2947) AAA_23 PF13476.6 KER32806.1 - 0.16 12.4 0.0 0.16 12.4 0.0 4.1 5 0 0 5 5 4 0 AAA domain Snf7 PF03357.21 KER32808.1 - 4.3e-24 85.0 15.0 5.1e-24 84.8 15.0 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 KER32808.1 - 0.0006 20.0 4.2 0.0006 20.0 4.2 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) ATPase PF06745.13 KER32808.1 - 0.0012 18.3 3.8 0.0015 18.0 3.8 1.0 1 0 0 1 1 1 1 KaiC DUF3584 PF12128.8 KER32808.1 - 0.014 13.0 6.2 0.017 12.7 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ACTL7A_N PF16840.5 KER32808.1 - 0.016 15.3 0.2 0.036 14.1 0.2 1.7 1 1 0 1 1 1 0 Actin-like protein 7A N-terminus DUF3585 PF12130.8 KER32808.1 - 0.025 14.7 5.1 0.035 14.3 5.1 1.4 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain E2F_CC-MB PF16421.5 KER32808.1 - 0.029 14.7 4.7 0.048 14.0 4.7 1.4 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain IFP_35_N PF07334.13 KER32808.1 - 0.031 14.3 4.5 0.043 13.9 0.9 2.5 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SIMPL PF04402.14 KER32808.1 - 0.07 13.6 2.7 0.079 13.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF4140 PF13600.6 KER32808.1 - 0.077 13.4 4.8 0.089 13.2 1.2 2.2 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YwqJ-deaminase PF14431.6 KER32808.1 - 0.088 13.0 0.2 0.14 12.3 0.2 1.3 1 1 0 1 1 1 0 YwqJ-like deaminase Vps53_N PF04100.12 KER32808.1 - 0.15 11.0 7.6 0.18 10.8 7.6 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF4337 PF14235.6 KER32808.1 - 0.15 12.1 5.1 0.068 13.3 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) CCDC-167 PF15188.6 KER32808.1 - 0.27 11.6 3.9 0.19 12.1 0.5 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 RasGAP_C PF03836.15 KER32808.1 - 0.29 11.3 9.2 0.78 9.9 9.2 1.7 1 1 0 1 1 1 0 RasGAP C-terminus FlaC_arch PF05377.11 KER32808.1 - 0.57 10.6 7.5 0.21 12.0 0.8 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2315 PF10231.9 KER32808.1 - 0.59 10.2 4.7 15 5.7 4.7 2.1 1 1 0 1 1 1 0 Apoptogenic protein 1 ABC_tran_CTD PF16326.5 KER32808.1 - 0.64 10.3 4.9 0.36 11.1 2.5 2.0 1 1 0 2 2 2 0 ABC transporter C-terminal domain DUF5082 PF16888.5 KER32808.1 - 1 9.7 11.4 2.9 8.2 2.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Cortex-I_coil PF09304.10 KER32808.1 - 1.5 9.0 9.4 1.6 9.0 3.5 2.3 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlxA PF14282.6 KER32808.1 - 1.6 8.8 12.3 3.6 7.6 11.5 2.0 1 1 0 1 1 1 0 FlxA-like protein FapA PF03961.13 KER32808.1 - 2 6.9 10.0 4.3 5.8 10.0 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Sec2p PF06428.11 KER32808.1 - 2.7 8.0 11.7 2 8.4 0.6 2.8 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 KER32808.1 - 3.4 7.7 15.7 0.13 12.2 1.9 2.9 1 1 1 3 3 3 0 Prefoldin subunit Enkurin PF13864.6 KER32808.1 - 4 7.9 10.1 0.78 10.2 0.5 2.2 2 0 0 2 2 2 0 Calmodulin-binding DivIC PF04977.15 KER32808.1 - 9.9 6.0 8.9 1.3 8.8 0.9 2.6 1 1 2 3 3 3 0 Septum formation initiator Snf7 PF03357.21 KER32809.1 - 8e-12 45.1 1.3 1.1e-11 44.6 1.3 1.1 1 0 0 1 1 1 1 Snf7 ABC_tran PF00005.27 KER32810.1 - 1.1e-33 116.6 0.0 4e-16 59.8 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KER32810.1 - 3.2e-10 40.3 4.0 0.1 12.4 1.0 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER32810.1 - 4.7e-09 36.0 4.7 0.015 14.8 0.8 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KER32810.1 - 1.5e-08 34.1 3.0 1.5e-08 34.1 3.0 2.0 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_22 PF13401.6 KER32810.1 - 2.4e-07 31.1 0.1 7.1e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KER32810.1 - 3.9e-06 27.3 0.0 0.069 13.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER32810.1 - 4.4e-06 27.2 0.0 0.036 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KER32810.1 - 4.6e-06 26.6 0.0 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase Fer4_6 PF12837.7 KER32810.1 - 1.4e-05 25.0 2.6 1.4e-05 25.0 2.6 1.9 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_21 PF14697.6 KER32810.1 - 2e-05 24.6 2.2 5.2e-05 23.3 2.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_15 PF13175.6 KER32810.1 - 2.2e-05 24.3 0.0 0.23 11.1 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KER32810.1 - 2.5e-05 24.3 0.3 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 KER32810.1 - 5.4e-05 23.8 0.2 0.013 16.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KER32810.1 - 0.00015 21.4 0.1 0.69 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 KER32810.1 - 0.0002 21.3 0.0 0.049 13.6 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 KER32810.1 - 0.00026 20.7 0.9 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.7 KER32810.1 - 0.00027 21.5 1.3 0.00093 19.7 0.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KER32810.1 - 0.00031 20.8 0.2 0.00067 19.7 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KER32810.1 - 0.00034 20.5 0.7 0.00034 20.5 0.7 1.9 2 0 0 2 2 1 1 4Fe-4S binding domain Thymidylate_kin PF02223.17 KER32810.1 - 0.00059 19.6 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase AAA_7 PF12775.7 KER32810.1 - 0.0011 18.6 0.0 0.33 10.5 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region Fer4_9 PF13187.6 KER32810.1 - 0.0014 18.7 1.4 0.0014 18.7 1.4 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 KER32810.1 - 0.0014 18.8 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KER32810.1 - 0.0018 18.3 0.0 0.077 13.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KER32810.1 - 0.0021 18.5 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KER32810.1 - 0.0039 17.7 0.1 6.3 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KER32810.1 - 0.0045 16.7 0.9 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KER32810.1 - 0.011 16.0 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 KER32810.1 - 0.015 15.8 1.3 0.025 15.1 0.3 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_5 PF07728.14 KER32810.1 - 0.018 15.1 0.1 1.8 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_16 PF13484.6 KER32810.1 - 0.018 16.0 2.9 0.018 15.9 0.6 2.2 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KER32810.1 - 0.021 14.9 0.2 7.3 6.7 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 KER32810.1 - 0.024 14.4 0.0 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_30 PF13604.6 KER32810.1 - 0.024 14.3 0.1 2.5 7.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KER32810.1 - 0.027 14.5 0.1 6 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.6 KER32810.1 - 0.039 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KER32810.1 - 0.051 14.1 3.0 0.15 12.7 3.0 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain NB-ARC PF00931.22 KER32810.1 - 0.07 12.3 0.0 4.6 6.4 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain Roc PF08477.13 KER32810.1 - 0.081 13.1 0.7 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KER32810.1 - 0.18 11.7 1.8 10 6.0 0.0 3.1 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 KER32810.1 - 0.22 10.8 0.2 6 6.1 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Fer4_22 PF17179.4 KER32810.1 - 1.5 9.7 4.0 1 10.2 1.9 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain Ion_trans PF00520.31 KER32811.1 - 8.6e-41 139.8 43.6 3.3e-16 59.3 11.2 6.9 4 2 2 6 6 6 5 Ion transport protein WHAMM-JMY_N PF15920.5 KER32811.1 - 0.27 11.1 1.8 41 4.1 0.0 3.6 4 0 0 4 4 4 0 N-terminal of Junction-mediating and WASP homolog-associated LRR_8 PF13855.6 KER32815.1 - 3.2e-15 55.6 14.6 1.3e-09 37.6 1.4 4.1 4 1 1 5 5 5 2 Leucine rich repeat LRR_5 PF13306.6 KER32815.1 - 6.3e-06 26.2 0.1 0.027 14.4 0.0 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 KER32815.1 - 0.00029 21.2 8.1 0.002 18.5 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KER32815.1 - 0.027 14.0 1.6 0.2 11.1 0.1 2.5 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 KER32815.1 - 0.31 11.2 3.4 3.6 7.9 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat PDZ PF00595.24 KER32816.1 - 2.9e-74 245.5 16.8 5.7e-14 52.2 0.1 7.4 6 1 1 7 7 7 6 PDZ domain PDZ_6 PF17820.1 KER32816.1 - 2.7e-47 158.4 24.0 7.2e-10 38.6 0.1 7.6 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 KER32816.1 - 4.5e-21 74.9 8.3 0.035 14.4 0.4 7.4 6 1 1 7 7 7 7 PDZ domain Guanylate_kin PF00625.21 KER32816.1 - 8.1e-09 35.4 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.6 KER32816.1 - 0.0004 20.3 10.1 9.9 6.2 0.1 5.8 6 0 0 6 6 6 2 Tricorn protease PDZ domain WW PF00397.26 KER32816.1 - 0.00091 19.3 0.4 0.0017 18.4 0.4 1.5 1 0 0 1 1 1 1 WW domain FYRC PF05965.14 KER32816.1 - 0.00097 19.3 0.8 43 4.4 0.0 4.9 5 0 0 5 5 5 0 F/Y rich C-terminus PDZ_4 PF17816.1 KER32816.1 - 0.11 12.9 1.7 1.2e+02 3.2 0.0 4.9 5 1 1 6 6 6 0 PDZ domain CpcD PF01383.21 KER32816.1 - 0.29 11.4 1.4 34 4.8 0.1 2.8 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain CBF PF03914.17 KER32817.1 - 2.2e-22 79.9 0.0 3.6e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 CBF/Mak21 family TBCA PF02970.16 KER32821.1 - 9.1e-22 77.2 1.1 1.1e-21 77.0 1.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF507 PF04368.13 KER32821.1 - 0.0031 17.5 0.8 0.0037 17.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF507) SCAMP PF04144.13 KER32824.1 - 8.9e-58 195.4 12.7 1.2e-57 195.0 12.7 1.1 1 0 0 1 1 1 1 SCAMP family T6SS_VasE PF05936.12 KER32824.1 - 0.0086 14.8 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE RRM_1 PF00076.22 KER32825.1 - 1e-17 63.7 0.0 2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KER32825.1 - 9e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KER32825.1 - 0.077 13.0 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KER32825.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif CTP_transf_like PF01467.26 KER32826.1 - 2e-20 73.4 0.0 2.5e-05 24.5 0.0 3.1 3 0 0 3 3 3 3 Cytidylyltransferase-like Cadherin PF00028.17 KER32829.1 - 8.5e-55 183.2 2.2 1.3e-17 64.0 0.2 9.3 8 1 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 KER32829.1 - 1.1e-08 34.7 0.0 0.00018 21.3 0.0 4.0 3 0 0 3 3 3 2 Cadherin-like PepSY PF03413.19 KER32829.1 - 0.0053 17.3 1.8 0.022 15.3 0.1 2.9 4 0 0 4 4 4 1 Peptidase propeptide and YPEB domain Phage_sheath_1N PF17481.2 KER32829.1 - 0.0056 17.1 0.0 0.089 13.3 0.0 2.6 2 0 0 2 2 2 1 Phage tail sheath protein beta-sandwich domain RET_CLD1 PF17756.1 KER32829.1 - 0.02 15.2 0.0 4.3 7.7 0.0 3.8 4 0 0 4 4 4 0 RET Cadherin like domain 1 DUF116 PF01976.17 KER32830.1 - 0.059 12.9 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF116 Sugar_tr PF00083.24 KER32831.1 - 2.2e-29 102.6 17.2 4.7e-29 101.5 17.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER32831.1 - 3.4e-18 65.7 27.3 5.5e-17 61.7 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cadherin PF00028.17 KER32833.1 - 1.8e-66 220.6 14.1 6.9e-17 61.7 0.5 10.3 9 1 1 10 10 10 9 Cadherin domain Cadherin_2 PF08266.12 KER32833.1 - 9.1e-09 35.0 0.4 5.8e-06 26.0 0.0 4.5 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 KER32833.1 - 0.0085 16.1 15.1 0.32 11.0 0.1 6.0 6 2 0 6 6 6 2 Cadherin-like Cadherin_4 PF17803.1 KER32833.1 - 0.12 13.0 0.1 0.12 13.0 0.1 5.5 6 0 0 6 6 6 0 Bacterial cadherin-like domain UPF0564 PF10595.9 KER32834.1 - 8.5e-31 107.3 31.6 1.3e-29 103.5 31.6 2.2 1 1 0 1 1 1 1 Uncharacterised protein family UPF0564 Cytochrom_B561 PF03188.16 KER32835.1 - 3.1e-35 121.3 5.8 3.1e-35 121.3 5.8 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KER32835.1 - 0.0021 17.8 2.1 0.0021 17.8 2.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) Phage_holin_3_6 PF07332.11 KER32835.1 - 0.048 13.7 0.4 0.048 13.7 0.4 3.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4079 PF13301.6 KER32835.1 - 0.093 12.9 5.6 0.028 14.6 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 KER32835.1 - 0.36 10.4 17.5 0.3 10.7 8.7 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Tetraspanin PF00335.20 KER32835.1 - 4.4 6.9 9.1 19 4.9 9.1 2.0 1 1 0 1 1 1 0 Tetraspanin family DUF3413 PF11893.8 KER32835.1 - 6.5 5.8 16.1 0.026 13.7 3.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3413) Myotub-related PF06602.14 KER32836.1 - 1.6e-111 372.7 0.0 2.2e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Mito_fiss_reg PF05308.11 KER32836.1 - 0.0015 18.6 0.4 0.0015 18.6 0.4 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator DSPc PF00782.20 KER32836.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PRKG1_interact PF15898.5 KER32836.1 - 0.34 11.8 1.0 0.68 10.9 1.0 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Motilin_assoc PF04643.12 KER32837.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide zf-AN1 PF01428.16 KER32838.1 - 1e-09 38.4 8.3 1e-09 38.4 8.3 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KER32838.1 - 0.14 12.6 5.3 0.26 11.7 5.3 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Filamin PF00630.19 KER32841.1 - 0 1035.8 27.0 4.5e-18 66.0 0.2 23.0 20 3 2 22 22 22 22 Filamin/ABP280 repeat CH PF00307.31 KER32841.1 - 3.4e-39 133.4 0.5 1.8e-21 76.4 0.2 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 KER32841.1 - 4.8e-16 58.5 1.0 0.14 12.1 0.0 8.9 10 0 0 10 10 10 4 Y_Y_Y domain Big_3_5 PF16640.5 KER32841.1 - 5.8e-13 48.8 15.7 2.4 8.4 0.0 12.5 13 0 0 13 13 12 3 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KER32841.1 - 3.7e-09 36.8 1.6 0.6 10.5 0.0 8.4 10 0 0 10 10 10 1 Invasin, domain 3 DUF5060 PF16586.5 KER32841.1 - 5.4e-06 26.7 0.0 8.3 6.9 0.0 9.1 12 0 0 12 12 11 1 Domain of unknown function (DUF5060) Wzt_C PF14524.6 KER32841.1 - 0.00011 22.2 0.3 16 5.5 0.0 5.0 6 0 0 6 6 6 1 Wzt C-terminal domain CAMSAP_CH PF11971.8 KER32841.1 - 0.00013 21.7 0.0 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KER32841.1 - 0.0093 16.1 0.1 0.41 10.8 0.0 2.3 2 0 0 2 2 2 1 CH-like domain in sperm protein EMP24_GP25L PF01105.24 KER32841.1 - 0.054 13.4 0.0 5.7 6.8 0.0 4.0 4 0 0 4 4 4 0 emp24/gp25L/p24 family/GOLD P53_C PF11619.8 KER32841.1 - 0.16 12.1 0.0 0.89 9.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain Bestrophin PF01062.21 KER32843.1 - 3.2e-64 217.2 4.5 4.2e-64 216.8 4.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Caveolin PF01146.17 KER32843.1 - 3.8 7.5 6.4 0.35 10.8 1.6 1.7 2 0 0 2 2 2 0 Caveolin Glucosamine_iso PF01182.20 KER32845.1 - 3.4e-19 69.6 0.0 4.2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NOA36 PF06524.12 KER32846.1 - 3.3e-73 246.7 31.7 4.6e-73 246.2 31.7 1.1 1 0 0 1 1 1 1 NOA36 protein SH3_9 PF14604.6 KER32847.1 - 1.1e-15 57.2 0.3 1.9e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain Abi_HHR PF07815.14 KER32847.1 - 1.5e-15 57.1 0.0 3.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 KER32847.1 - 1.9e-12 46.6 0.3 3.1e-12 45.9 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KER32847.1 - 1.5e-11 43.8 0.1 3.9e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Hyccin PF09790.9 KER32849.1 - 2.1e-18 66.5 1.8 5.7e-18 65.1 1.8 1.7 1 1 0 1 1 1 1 Hyccin MMR_HSR1 PF01926.23 KER32851.1 - 3.1e-07 30.5 0.0 1.7e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER32851.1 - 0.00046 19.8 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KER32851.1 - 0.061 13.5 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KER32851.1 - 0.071 13.0 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Ras PF00071.22 KER32851.1 - 0.078 12.6 0.0 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Ras family F-box PF00646.33 KER32851.1 - 0.63 10.0 2.2 1.9 8.4 0.3 2.6 2 0 0 2 2 2 0 F-box domain RVT_1 PF00078.27 KER32852.1 - 2e-13 50.4 0.0 2.1e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoLip_ATPase_N PF16209.5 KER32854.1 - 1e-23 82.8 1.0 1e-23 82.8 1.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KER32854.1 - 4.9e-06 26.2 0.0 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_C PF16212.5 KER32855.1 - 1.6e-63 214.7 22.2 2.5e-63 214.1 22.2 1.3 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KER32855.1 - 1.7e-07 31.8 0.0 0.00015 22.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KER32855.1 - 0.00025 20.9 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.18 KER32855.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Telomere recombination His_Phos_1 PF00300.22 KER32856.1 - 1.6e-12 47.5 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.22 KER32858.1 - 2.3e-19 67.8 11.2 0.00048 20.2 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat Arm PF00514.23 KER32858.1 - 2.1e-16 59.3 7.6 0.0014 18.6 0.0 6.3 6 1 1 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KER32858.1 - 3.1e-14 53.1 7.1 1e-11 45.0 0.7 4.3 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KER32858.1 - 1e-10 41.9 2.2 1.9e-06 28.0 0.1 3.5 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KER32858.1 - 1.2e-09 38.5 0.1 0.00089 19.7 0.0 4.5 4 0 0 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 KER32858.1 - 7.9e-07 28.0 3.0 5.9e-06 25.1 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 KER32858.1 - 9e-06 24.5 0.8 0.0016 17.1 0.0 3.0 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 KER32858.1 - 1.9e-05 24.8 0.0 0.0095 16.2 0.0 3.2 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KER32858.1 - 0.00027 20.5 0.2 0.00064 19.3 0.0 1.8 2 1 0 2 2 2 1 Armadillo-like IFRD PF05004.13 KER32858.1 - 0.0029 16.7 2.1 0.24 10.5 0.2 3.8 2 1 2 4 4 4 2 Interferon-related developmental regulator (IFRD) STAR_dimer PF16544.5 KER32858.1 - 0.0053 16.3 0.1 0.026 14.1 0.0 2.2 3 0 0 3 3 2 1 Homodimerisation region of STAR domain protein DUF3636 PF12331.8 KER32858.1 - 0.013 15.4 0.1 0.98 9.2 0.0 3.3 1 1 2 4 4 4 0 Protein of unknown function (DUF3636) TAF6_C PF07571.13 KER32858.1 - 0.018 15.4 0.2 0.44 10.9 0.1 2.6 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 KER32858.1 - 0.021 15.4 0.1 6.8 7.4 0.0 3.2 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KER32858.1 - 0.037 14.2 1.5 27 5.0 0.1 3.4 2 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KER32858.1 - 0.064 14.0 5.3 1.9 9.4 0.0 4.3 5 1 0 5 5 2 0 PBS lyase HEAT-like repeat GP88 PF17338.2 KER32858.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Gene product 88 Tti2 PF10521.9 KER32858.1 - 0.09 12.3 0.3 3.8 7.0 0.1 2.9 2 1 0 3 3 3 0 Tti2 family V-ATPase_H_C PF11698.8 KER32858.1 - 0.12 12.5 0.1 2.1 8.5 0.0 2.9 1 1 1 3 3 3 0 V-ATPase subunit H API5 PF05918.11 KER32858.1 - 0.14 11.0 0.1 4.7 5.9 0.0 2.4 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF2019 PF09450.10 KER32858.1 - 0.33 10.9 1.7 6.7 6.7 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF2019) CUT PF02376.15 KER32859.1 - 2.3e-32 110.9 1.2 3.3e-32 110.5 0.3 1.7 2 0 0 2 2 2 1 CUT domain Homeodomain PF00046.29 KER32859.1 - 5.4e-11 42.2 1.4 1.1e-10 41.2 1.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER32859.1 - 7.1e-05 22.6 0.1 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Methyltrn_RNA_4 PF09936.9 KER32859.1 - 0.079 12.8 0.3 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase MH2 PF03166.14 KER32862.1 - 4.1e-74 248.8 0.8 5.4e-74 248.4 0.8 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 KER32862.1 - 1.6e-41 140.6 1.0 3.3e-41 139.7 0.3 1.9 3 0 0 3 3 3 1 MH1 domain IRF-3 PF10401.9 KER32862.1 - 0.005 16.6 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.6 KER32862.1 - 0.11 12.5 0.6 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Acetyltransf_1 PF00583.25 KER32864.1 - 8e-09 35.8 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER32864.1 - 7.2e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KER32864.1 - 0.00043 20.6 0.0 0.00065 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER32864.1 - 0.00056 19.8 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KER32864.1 - 0.0031 17.6 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KER32864.1 - 0.025 15.2 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dec-1 PF04624.14 KER32866.1 - 2.8 7.8 12.9 3.2 7.7 0.1 3.6 3 0 0 3 3 3 0 Dec-1 repeat Dec-1 PF04624.14 KER32869.1 - 0.0012 18.6 1.5 1.6 8.6 0.1 2.7 2 0 0 2 2 2 2 Dec-1 repeat Carb_kinase PF01256.17 KER32870.1 - 1.8e-54 184.8 0.0 2.2e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase DUF3692 PF12469.8 KER32870.1 - 0.035 14.3 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein HLH PF00010.26 KER32871.1 - 1.3e-15 57.0 1.9 2.9e-15 55.9 1.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 KER32871.1 - 0.11 13.0 0.7 0.35 11.4 0.7 1.8 1 0 0 1 1 1 0 Cell division protein ZapB MatE PF01554.18 KER32872.1 - 5.3e-38 130.2 19.6 3.5e-24 85.3 3.9 3.8 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KER32872.1 - 0.0014 18.7 3.5 0.0014 18.7 3.5 4.7 7 0 0 7 7 7 2 Polysaccharide biosynthesis C-terminal domain Claudin_2 PF13903.6 KER32872.1 - 0.023 14.5 0.2 0.023 14.5 0.2 2.4 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction TMEM52 PF14979.6 KER32872.1 - 0.34 10.8 2.4 0.61 10.0 0.1 2.3 1 1 1 2 2 2 0 Transmembrane 52 FOLN PF09289.10 KER32874.1 - 0.25 11.6 1.0 0.72 10.1 1.0 1.9 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Asp PF00026.23 KER32876.1 - 4.6e-42 144.5 0.0 5.9e-30 104.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KER32876.1 - 3.5e-13 50.2 0.0 1.4e-07 31.9 0.0 3.3 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KER32876.1 - 0.0015 19.1 0.1 1.3 9.8 0.0 2.8 2 2 0 2 2 2 2 Aspartyl protease Ribosomal_S3Ae PF01015.18 KER32877.1 - 4e-80 268.2 1.6 4.6e-80 268.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family PMM PF03332.13 KER32877.1 - 0.048 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase DHHC PF01529.20 KER32878.1 - 8.5e-35 119.8 12.0 8.5e-35 119.8 12.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase MctB PF11382.8 KER32878.1 - 0.061 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF4209 PF13910.6 KER32879.1 - 4.9e-16 58.7 0.8 2.1e-15 56.7 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) Aa_trans PF01490.18 KER32880.1 - 1.2e-64 218.5 29.2 1.5e-64 218.2 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ldl_recept_a PF00057.18 KER32881.1 - 7.8e-07 29.2 9.1 1.5e-06 28.3 9.1 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A LapA_dom PF06305.11 KER32881.1 - 0.029 14.2 1.1 0.035 13.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TMEM132D_C PF15706.5 KER32881.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term THEG4 PF15834.5 KER32881.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 SET PF00856.28 KER32882.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SET domain UL41A PF17591.2 KER32882.1 - 0.072 13.2 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A Cofilin_ADF PF00241.20 KER32886.1 - 1.7e-18 66.6 0.0 2.9e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TIR_2 PF13676.6 KER32887.1 - 1.4e-14 54.7 0.0 4.5e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 TIR domain SAM_1 PF00536.30 KER32887.1 - 0.00059 20.2 0.4 0.005 17.2 0.4 2.2 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) V-ATPase_H_N PF03224.14 KER32887.1 - 0.019 14.3 0.1 0.041 13.2 0.1 1.6 1 0 0 1 1 1 0 V-ATPase subunit H SAM_PNT PF02198.16 KER32887.1 - 0.13 12.2 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain RVT_1 PF00078.27 KER32888.1 - 3e-34 118.5 0.0 6.1e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIR_2 PF13676.6 KER32888.1 - 3.6e-06 27.6 0.0 1.2e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 TIR domain SAM_3 PF18016.1 KER32888.1 - 0.022 14.5 0.1 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RTP1_C1 PF10363.9 KER32888.1 - 0.051 13.8 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 SAM_1 PF00536.30 KER32888.1 - 0.16 12.4 0.1 0.76 10.3 0.0 2.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) adh_short PF00106.25 KER32889.1 - 3e-39 134.5 0.0 1.2e-38 132.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER32889.1 - 6.8e-23 81.4 0.0 2.3e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER32889.1 - 0.0005 20.0 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 KR domain Usp PF00582.26 KER32890.1 - 7.7e-20 71.8 0.0 1.3e-19 71.1 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family Sec3_C PF09763.9 KER32892.1 - 9.3e-78 262.3 25.2 3.2e-70 237.4 16.8 3.6 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KER32892.1 - 0.00024 21.1 0.1 0.00067 19.7 0.1 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH NifQ PF04891.12 KER32892.1 - 0.018 15.4 0.3 0.14 12.5 0.0 2.6 1 1 1 2 2 2 0 NifQ BCIP PF13862.6 KER32892.1 - 0.038 13.8 1.4 0.11 12.3 1.4 1.8 1 0 0 1 1 1 0 p21-C-terminal region-binding protein RhoGAP-FF1 PF16512.5 KER32892.1 - 0.59 10.8 3.0 46 4.8 0.1 4.1 3 1 1 4 4 4 0 p190-A and -B Rho GAPs FF domain BORCS7 PF16088.5 KER32892.1 - 0.69 10.2 9.8 11 6.3 0.6 3.4 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 TipAS PF07739.13 KER32892.1 - 3.3 8.3 7.2 7.3 7.2 0.1 3.7 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain RMI1_C PF16099.5 KER32892.1 - 5.6 6.8 7.9 13 5.7 0.0 3.9 4 1 0 4 4 4 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Casc1_N PF15927.5 KER32892.1 - 8.1 6.1 9.4 5.7 6.6 0.7 3.7 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 N-terminus HMG_box_2 PF09011.10 KER32894.1 - 2.9e-34 117.5 9.6 2.9e-21 75.8 1.7 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KER32894.1 - 3.4e-33 113.9 8.4 2.4e-17 63.1 1.4 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.6 KER32894.1 - 0.063 13.3 6.8 0.11 12.5 1.5 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Retrotrans_gag PF03732.17 KER32896.1 - 0.0001 22.5 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Phage_XkdX PF09693.10 KER32898.1 - 0.17 12.0 0.2 0.29 11.2 0.2 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Nup54_57_C PF18570.1 KER32898.1 - 0.54 9.9 3.8 0.32 10.6 0.4 2.1 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Ribosomal_S11 PF00411.19 KER32899.1 - 1.9e-16 60.5 0.2 2.8e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Chor_lyase PF04345.13 KER32900.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Chorismate lyase gpD PF02925.16 KER32900.1 - 0.2 11.6 0.0 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage scaffolding protein D MFS_1 PF07690.16 KER32901.1 - 7.3e-15 54.7 22.6 7.3e-15 54.7 22.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KER32902.1 - 2.1e-13 50.0 16.6 2.1e-13 50.0 16.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KER32904.1 - 1.8e-17 63.3 20.2 1.8e-17 63.3 20.2 2.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Neurensin PF14927.6 KER32905.1 - 0.06 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Neurensin MFS_1 PF07690.16 KER32906.1 - 3.3e-15 55.9 10.8 4.8e-15 55.3 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_60s PF00428.19 KER32909.1 - 2.8e-24 85.5 12.6 4.9e-24 84.7 12.6 1.4 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF4641 PF15483.6 KER32909.1 - 0.016 14.4 1.4 0.015 14.4 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Cytomega_UL84 PF06284.11 KER32909.1 - 0.04 12.4 0.8 0.05 12.1 0.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Methyltransf_10 PF05971.12 KER32910.1 - 1.9e-68 231.0 0.0 2.8e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KER32910.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KER32910.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KER32910.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DHO_dh PF01180.21 KER32911.1 - 8.7e-34 117.1 0.0 1.4e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 KER32911.1 - 8e-32 109.4 0.2 1.8e-31 108.2 0.2 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KER32911.1 - 3.1e-13 49.6 0.0 2.1e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KER32911.1 - 5.8e-07 29.7 0.0 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KER32911.1 - 9.7e-05 21.8 0.0 0.061 12.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KER32911.1 - 0.00011 22.6 0.0 0.11 13.0 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KER32911.1 - 0.037 14.5 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KER32911.1 - 0.094 12.8 0.0 0.87 9.6 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KER32911.1 - 0.13 11.6 0.0 15 4.8 0.0 2.3 2 0 0 2 2 2 0 ThiF family Dus PF01207.17 KER32911.1 - 0.2 10.7 0.1 1.1 8.2 0.1 1.9 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Fer4_10 PF13237.6 KER32911.1 - 3.6 7.8 7.5 15 5.8 7.6 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain ANAPC4_WD40 PF12894.7 KER32914.1 - 9.4e-09 35.5 1.1 0.0003 21.0 0.0 4.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER32914.1 - 2.7e-08 34.3 26.8 0.00019 22.1 1.4 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 KER32914.1 - 0.15 12.1 0.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat YajC PF02699.15 KER32916.1 - 0.1 12.5 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit MBOAT PF03062.19 KER32917.1 - 1.1e-31 110.4 31.5 1.1e-31 110.4 31.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KER32917.1 - 0.091 13.0 11.4 0.022 15.0 6.5 2.5 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family LIM PF00412.22 KER32919.1 - 1.9e-25 88.9 41.6 1.2e-09 38.3 6.5 3.7 3 1 0 3 3 3 3 LIM domain tRNA-synt_1g PF09334.11 KER32919.1 - 6.6 5.4 5.8 9.9 4.8 5.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) GST_N_3 PF13417.6 KER32921.1 - 1e-16 61.1 0.0 3.2e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KER32921.1 - 3.6e-15 56.0 0.0 6.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER32921.1 - 4e-15 55.9 0.1 2.3e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KER32921.1 - 0.00035 20.7 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER32921.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KER32921.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KER32921.1 - 0.0042 17.8 0.0 0.075 13.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KER32921.1 - 0.0057 16.8 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Tom37 PF10568.9 KER32921.1 - 0.072 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Transglut_N PF00868.20 KER32924.1 - 0.081 13.3 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Transglutaminase family DUF1480 PF07351.13 KER32924.1 - 0.086 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) SPRY PF00622.28 KER32926.1 - 2.4e-08 34.1 0.2 8.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_4 PF15227.6 KER32926.1 - 7.7e-06 26.0 5.5 7.7e-06 26.0 5.5 4.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KER32926.1 - 2e-05 24.4 3.5 2e-05 24.4 3.5 4.1 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KER32926.1 - 8.6e-05 22.5 6.5 8.6e-05 22.5 6.5 4.3 4 0 0 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER32926.1 - 0.0002 21.1 2.6 0.0002 21.1 2.6 4.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER32926.1 - 0.00033 20.5 3.2 0.00033 20.5 3.2 5.2 5 0 0 5 5 4 1 zinc-RING finger domain fn3 PF00041.21 KER32926.1 - 0.0013 19.0 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_2 PF13923.6 KER32926.1 - 0.004 17.0 5.9 0.004 17.0 5.9 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KER32926.1 - 0.0046 17.1 7.7 0.0046 17.1 7.7 4.4 5 0 0 5 5 4 2 B-box zinc finger FlgN PF05130.12 KER32926.1 - 0.03 14.8 7.4 0.055 14.0 7.4 1.3 1 0 0 1 1 1 0 FlgN protein Pur_ac_phosph_N PF16656.5 KER32926.1 - 0.062 13.9 0.0 0.21 12.2 0.0 1.9 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain IBR PF01485.21 KER32926.1 - 1.6 9.0 31.7 1.4 9.2 11.9 4.5 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain DUF382 PF04037.13 KER32927.1 - 2.8e-58 195.6 1.0 4.6e-58 194.9 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KER32927.1 - 9.1e-21 73.5 4.4 1.8e-20 72.5 4.4 1.5 1 0 0 1 1 1 1 PSP Exo_endo_phos_2 PF14529.6 KER32927.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase EGF PF00008.27 KER32930.1 - 6.1e-06 26.4 5.9 6.1e-06 26.4 5.9 2.5 2 0 0 2 2 2 1 EGF-like domain DSL PF01414.19 KER32930.1 - 3.4e-05 24.0 2.7 3.4e-05 24.0 2.7 2.9 1 1 1 2 2 2 1 Delta serrate ligand EGF_2 PF07974.13 KER32930.1 - 0.0071 16.7 7.2 0.13 12.6 4.5 3.3 3 0 0 3 3 3 1 EGF-like domain SIT PF15330.6 KER32930.1 - 0.017 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Laminin_EGF PF00053.24 KER32930.1 - 2.3 8.4 11.5 54 4.0 9.5 3.0 1 1 1 2 2 2 0 Laminin EGF domain hEGF PF12661.7 KER32930.1 - 2.8 8.7 10.9 0.18 12.5 3.7 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF SH3_10 PF17902.1 KER32931.1 - 6.3e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain RVT_1 PF00078.27 KER32932.1 - 9.9e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NitrOD5 PF11537.8 KER32932.1 - 0.054 13.6 0.1 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 Nitrosopumilus output domain 5 TMEM61 PF15105.6 KER32934.1 - 0.021 14.7 0.3 2 8.2 0.2 2.6 2 0 0 2 2 2 0 TMEM61 protein family TTL PF03133.15 KER32935.1 - 1.8e-38 132.3 0.0 3e-30 105.4 0.0 2.7 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KER32935.1 - 0.00099 18.4 0.0 1.1 8.5 0.0 3.0 4 0 0 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KER32935.1 - 0.03 13.6 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Kelch_1 PF01344.25 KER32936.1 - 3.6e-54 180.1 2.1 1.9e-10 40.2 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KER32936.1 - 7.3e-32 108.6 2.3 5.7e-07 29.6 0.0 5.6 3 2 3 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KER32936.1 - 3.9e-24 84.4 0.1 6.8e-08 32.4 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KER32936.1 - 6.8e-19 67.4 0.2 0.00073 19.5 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KER32936.1 - 2.7e-17 62.0 0.0 0.011 15.7 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KER32936.1 - 5.6e-06 26.5 14.1 0.016 15.5 0.3 5.5 8 0 0 8 8 8 2 Galactose oxidase, central domain PQQ_3 PF13570.6 KER32936.1 - 0.046 14.2 1.8 5.7 7.6 0.0 4.0 3 1 0 3 3 3 0 PQQ-like domain DUF1668 PF07893.13 KER32936.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Laminin_G_2 PF02210.24 KER32938.1 - 6.2e-33 114.1 1.8 1.7e-17 64.2 0.1 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 KER32938.1 - 1.8e-25 89.6 0.0 2.1e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 KER32938.1 - 0.00025 21.3 1.3 0.0006 20.0 1.3 1.7 1 0 0 1 1 1 1 EGF-like domain Cadherin_C_2 PF16492.5 KER32938.1 - 0.1 13.4 0.1 0.26 12.1 0.1 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EGF_2 PF07974.13 KER32938.1 - 0.16 12.4 4.5 0.32 11.4 4.5 1.5 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 KER32938.1 - 0.28 11.9 1.6 0.9 10.3 1.6 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Rad51 PF08423.11 KER32942.1 - 4.3e-130 432.5 0.0 5.2e-130 432.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KER32942.1 - 7.5e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KER32942.1 - 2e-09 37.3 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KER32942.1 - 2.4e-06 28.1 1.2 5.4e-06 26.9 1.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KER32942.1 - 9.5e-06 25.1 0.9 4e-05 23.1 0.9 1.9 1 1 0 1 1 1 1 KaiC HhH-GPD PF00730.25 KER32942.1 - 0.012 16.0 0.0 0.043 14.3 0.0 1.9 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein MCD PF05292.11 KER32942.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain AAA_28 PF13521.6 KER32942.1 - 0.034 14.4 0.6 0.061 13.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain ssDNA_TraI_N PF18272.1 KER32942.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Ig_3 PF13927.6 KER32945.1 - 6e-07 30.0 0.3 0.028 15.0 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 KER32945.1 - 3.8e-05 23.8 0.3 0.055 13.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_6 PF18452.1 KER32945.1 - 0.00029 20.3 0.3 1 9.0 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER32945.1 - 0.00039 20.4 0.1 0.038 14.0 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 KER32945.1 - 0.00045 20.3 3.3 0.035 14.3 0.1 3.2 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 KER32945.1 - 0.11 12.8 0.2 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Herpes_UL52 PF03121.15 KER32947.1 - 0.051 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Homeodomain PF00046.29 KER32948.1 - 2.1e-21 75.5 2.8 4e-21 74.6 2.8 1.5 1 0 0 1 1 1 1 Homeodomain ODAM PF15424.6 KER32949.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family 7tm_1 PF00001.21 KER32950.1 - 2.2e-07 30.5 20.6 2.2e-07 30.5 20.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Sdh_cyt PF01127.22 KER32950.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.7 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7tm_1 PF00001.21 KER32951.1 - 2.4e-05 23.8 22.8 4.8e-05 22.8 20.8 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3051 PF11252.8 KER32951.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3051) 4F5 PF04419.14 KER32952.1 - 9.9e-10 39.1 9.3 1.8e-09 38.3 9.3 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 KER32952.1 - 0.0024 18.2 0.1 0.0056 17.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF629 PF04780.12 KER32952.1 - 0.021 13.4 0.1 0.03 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 KER32952.1 - 0.059 14.2 2.9 0.12 13.3 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met2 PF12907.7 KER32952.1 - 0.46 10.7 4.7 1.5 9.0 4.7 1.9 1 1 0 1 1 1 0 Zinc-binding DLH PF01738.18 KER32953.1 - 2.3e-13 50.2 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FoP_duplication PF13865.6 KER32955.1 - 2.8 8.6 6.1 9.3 6.9 0.1 3.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SDA1 PF05285.12 KER32956.1 - 0.12 11.8 43.6 0.14 11.6 43.6 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KER32956.1 - 4.4 6.6 38.6 4.8 6.4 38.6 1.1 1 0 0 1 1 1 0 BUD22 F5_F8_type_C PF00754.25 KER32958.1 - 7.7e-06 26.1 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 F5/8 type C domain Telomerase_RBD PF12009.8 KER32959.1 - 0.024 14.7 0.0 8.1 6.6 0.0 2.4 3 0 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain BPD_transp_2 PF02653.16 KER32960.1 - 0.083 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF4817 PF16087.5 KER32963.1 - 0.0027 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) DXPR_C PF13288.6 KER32963.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain UCR_6-4kD PF08997.10 KER32966.1 - 0.27 11.2 0.7 8.1 6.5 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein E1_DerP2_DerF2 PF02221.15 KER32967.1 - 5.4e-09 36.6 0.1 6.7e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 ML domain PlyB_C PF18684.1 KER32967.1 - 0.059 13.1 0.1 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 Pleurotolysin B C-terminal domain N_BRCA1_IG PF16158.5 KER32967.1 - 0.093 13.5 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 Ig-like domain from next to BRCA1 gene IL4_i_Ig PF18258.1 KER32969.1 - 5e-20 71.5 0.9 1.9e-19 69.7 0.9 2.0 1 1 0 1 1 1 1 Interleukin-4 inducing immunoglobulin-binding domain Ntox6 PF15544.6 KER32970.1 - 0.055 13.0 0.0 0.059 12.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial toxin 6 CIDE-N PF02017.15 KER32970.1 - 0.07 13.2 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 CIDE-N domain TcdB_N PF12918.7 KER32970.1 - 0.083 13.2 0.1 11 6.4 0.1 2.1 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Forkhead PF00250.18 KER32971.1 - 1.6e-36 124.4 0.2 3.1e-36 123.5 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain DNA_pol_phi PF04931.13 KER32972.1 - 1.4 7.0 3.2 1.4 6.9 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi BNR_assoc_N PF14873.6 KER32973.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.6 1 1 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase WAC_Acf1_DNA_bd PF10537.9 KER32973.1 - 0.11 13.0 2.0 0.24 12.0 2.0 1.5 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal EGF PF00008.27 KER32975.1 - 2e-20 72.7 134.4 4.8e-07 30.0 2.7 11.9 11 1 0 11 11 11 6 EGF-like domain DSL PF01414.19 KER32975.1 - 8.3e-18 64.4 4.6 8.3e-18 64.4 4.6 7.7 5 2 2 7 7 7 1 Delta serrate ligand EGF_2 PF07974.13 KER32975.1 - 3.8e-12 46.3 141.2 0.00085 19.6 10.4 11.1 10 0 0 10 10 10 6 EGF-like domain hEGF PF12661.7 KER32975.1 - 5.5e-10 39.5 100.4 0.00068 20.2 6.1 11.2 10 0 0 10 10 10 6 Human growth factor-like EGF EGF_CA PF07645.15 KER32975.1 - 0.00014 22.0 3.2 0.00014 22.0 3.2 10.0 5 2 4 9 9 9 2 Calcium-binding EGF domain RRM_1 PF00076.22 KER32976.1 - 7.3e-39 131.4 0.2 1.1e-17 63.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2844 PF11005.8 KER32976.1 - 0.024 14.7 0.0 0.073 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) TERF2_RBM PF16772.5 KER32976.1 - 0.087 12.3 0.8 0.53 9.7 0.1 2.3 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif DUF1387 PF07139.11 KER32976.1 - 2 8.1 19.0 12 5.5 16.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Penaeidin PF05927.11 KER32977.1 - 0.031 15.0 1.8 0.039 14.7 1.8 1.1 1 0 0 1 1 1 0 Penaeidin DUF2471 PF10616.9 KER32978.1 - 0.042 14.4 0.0 0.046 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2471) LIM PF00412.22 KER32981.1 - 1e-31 108.9 15.8 3e-16 59.4 1.4 2.3 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 KER32981.1 - 1.8e-18 66.1 0.4 3.6e-18 65.1 0.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER32981.1 - 0.0018 18.1 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain VATC PF18716.1 KER32981.1 - 6 6.8 12.0 0.22 11.4 1.7 3.4 4 0 0 4 4 4 0 Vms1-associating treble clef domain PHF5 PF03660.14 KER32981.1 - 8.1 6.7 11.6 0.43 10.8 0.8 2.3 1 1 1 2 2 2 0 PHF5-like protein WH1 PF00568.23 KER32982.1 - 1.9e-12 47.1 0.1 2.9e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 KER32982.1 - 0.014 14.9 0.3 0.014 14.9 0.3 1.5 2 0 0 2 2 2 0 VASP tetramerisation domain RasGEF PF00617.19 KER32986.1 - 2.1e-50 171.4 3.4 4.1e-50 170.4 3.4 1.5 1 0 0 1 1 1 1 RasGEF domain CSN8_PSD8_EIF3K PF10075.9 KER32988.1 - 3.6e-16 59.4 0.0 3.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family PCI PF01399.27 KER32988.1 - 0.0078 16.7 0.2 0.014 15.9 0.2 1.7 1 1 0 1 1 1 1 PCI domain Fer2_3 PF13085.6 KER32989.1 - 6.1e-33 113.1 0.0 9.7e-33 112.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KER32989.1 - 5.9e-09 36.3 4.5 5.9e-09 36.3 4.5 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KER32989.1 - 3.2e-08 33.6 2.2 3.2e-08 33.6 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KER32989.1 - 9.4e-08 32.4 6.8 9.4e-08 32.4 6.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KER32989.1 - 0.002 18.7 5.1 0.002 18.7 5.1 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KER32989.1 - 0.011 15.7 2.8 0.016 15.2 0.2 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KER32989.1 - 0.026 14.7 0.3 0.3 11.3 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KER32989.1 - 0.11 12.7 13.6 0.084 13.0 9.1 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 KER32989.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding BUD22 PF09073.10 KER32992.1 - 1.1e-05 25.0 4.1 1.1e-05 25.0 4.1 2.9 1 1 0 2 2 2 1 BUD22 DUF3367 PF11847.8 KER32993.1 - 0.62 7.9 3.1 1 7.2 3.1 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase RabGAP-TBC PF00566.18 KER32994.1 - 7.7e-48 163.0 1.2 1.4e-40 139.2 0.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RVT_1 PF00078.27 KER32994.1 - 6.7e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_phi PF04931.13 KER32994.1 - 0.0035 15.5 41.0 0.0056 14.9 41.0 1.2 1 0 0 1 1 1 1 DNA polymerase phi PH PF00169.29 KER32994.1 - 0.01 16.3 0.2 0.067 13.7 0.0 2.5 2 0 0 2 2 2 0 PH domain TFB6 PF17110.5 KER32994.1 - 0.11 12.2 10.7 0.31 10.8 10.7 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 KER32994.1 - 0.12 10.5 31.2 0.19 9.9 31.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KER32994.1 - 0.79 9.1 31.6 1.4 8.3 31.6 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 KER32994.1 - 1.7 7.1 27.8 3.3 6.1 27.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.12 KER32994.1 - 2.6 6.4 24.3 0.43 9.0 19.9 1.8 2 0 0 2 2 2 0 Mpp10 protein SAPS PF04499.15 KER32994.1 - 4 6.1 9.3 7.9 5.1 9.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mito_carr PF00153.27 KER32995.1 - 7.4e-78 256.6 6.5 9.2e-21 73.6 0.2 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein EF-hand_7 PF13499.6 KER32995.1 - 2.4e-13 50.3 1.0 9e-06 26.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER32995.1 - 8.7e-12 44.0 0.9 9.2e-05 22.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KER32995.1 - 1.2e-09 37.0 1.1 0.00081 18.8 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 KER32995.1 - 8.4e-09 34.5 6.5 0.00035 19.9 0.1 3.3 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 KER32995.1 - 6.7e-07 29.1 0.2 0.047 13.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair DUF2666 PF10869.8 KER32995.1 - 0.00072 19.8 0.2 1.8 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2666) EF-hand_9 PF14658.6 KER32995.1 - 0.0069 16.7 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KER32995.1 - 0.043 14.1 0.6 4.3 7.7 0.0 2.6 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 KER32995.1 - 0.047 13.9 0.7 0.096 12.9 0.1 1.8 2 0 0 2 2 2 0 Dockerin type I domain SurE PF01975.17 KER32995.1 - 0.056 13.2 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Survival protein SurE Histone PF00125.24 KER32997.1 - 1.2e-21 77.4 0.0 1.3e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Methyltransf_23 PF13489.6 KER32998.1 - 8.8e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER32998.1 - 1.9e-12 47.7 0.0 5.8e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KER32998.1 - 7e-10 39.5 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER32998.1 - 2.2e-07 31.5 0.0 5.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER32998.1 - 1.9e-05 24.5 0.1 0.0002 21.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KER32998.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KER32998.1 - 0.0024 17.8 0.0 0.0053 16.6 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 KER32998.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KER32998.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 KER32998.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 KER32998.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPR_19 PF14559.6 KER32999.1 - 1.9e-12 47.5 14.1 0.0021 18.5 0.1 7.2 6 2 2 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KER32999.1 - 1e-09 38.5 25.9 3.2e-05 24.1 1.5 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KER32999.1 - 5.1e-06 26.9 6.2 0.45 11.5 0.1 7.4 9 1 0 9 9 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KER32999.1 - 1.3e-05 25.2 0.1 0.11 12.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER32999.1 - 1.6e-05 24.6 4.6 0.11 12.6 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KER32999.1 - 7.3e-05 22.3 0.4 7.3e-05 22.3 0.4 2.5 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_6 PF13174.6 KER32999.1 - 0.0015 19.0 15.2 3.5 8.5 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER32999.1 - 0.0028 17.7 28.1 0.058 13.5 0.6 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KER32999.1 - 0.0033 17.4 0.1 0.0033 17.4 0.1 4.2 4 1 1 5 5 5 2 Putative TPR-like repeat TPR_12 PF13424.6 KER32999.1 - 0.0034 17.6 16.6 0.93 9.8 1.0 6.4 4 3 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER32999.1 - 0.0047 17.6 5.6 0.29 11.8 0.4 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat PPR_2 PF13041.6 KER32999.1 - 0.015 15.5 0.7 2 8.7 0.0 3.6 4 1 1 5 5 3 0 PPR repeat family PPR PF01535.20 KER32999.1 - 0.069 13.4 5.1 30 5.2 0.1 5.1 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.6 KER32999.1 - 1 9.7 18.6 0.92 9.9 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KER32999.1 - 2.5 8.1 24.8 0.35 10.8 0.2 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 KER33001.1 - 1.7e-32 112.8 0.0 9e-30 104.0 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KER33001.1 - 5.4e-20 71.3 0.1 1.2e-19 70.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KER33001.1 - 4.3e-14 52.3 0.0 8e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KER33001.1 - 1.7e-10 40.8 0.0 4.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GAGA PF09237.11 KER33002.1 - 0.088 12.6 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 GAGA factor HSP20 PF00011.21 KER33003.1 - 0.038 14.1 0.0 5.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Hsp20/alpha crystallin family Band_7 PF01145.25 KER33006.1 - 2.5e-28 99.3 3.6 4.4e-28 98.5 3.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER33006.1 - 0.0046 16.7 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family CAP PF00188.26 KER33009.1 - 1.1e-14 55.4 0.1 2e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-C2H2 PF00096.26 KER33009.1 - 0.0032 17.8 2.9 0.0088 16.5 2.9 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER33009.1 - 0.46 11.4 3.0 1.4 10.0 3.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger CAP PF00188.26 KER33010.1 - 5.7e-18 66.0 0.1 7.3e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KER33011.1 - 1.1e-18 68.2 0.2 1.6e-18 67.8 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Auts2 PF15336.6 KER33011.1 - 1.1 9.3 7.7 1.5 8.9 7.7 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein CAP PF00188.26 KER33012.1 - 6.1e-19 69.1 2.7 6.1e-19 69.1 2.7 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family MAP7 PF05672.11 KER33012.1 - 0.0027 17.4 21.3 0.0027 17.4 21.3 1.7 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family RR_TM4-6 PF06459.12 KER33012.1 - 0.052 13.4 7.4 0.08 12.8 7.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 KER33012.1 - 0.13 12.6 1.7 0.23 11.8 1.7 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 KER33012.1 - 0.15 10.8 2.8 0.14 10.9 2.8 1.2 1 0 0 1 1 1 0 Presenilin Auts2 PF15336.6 KER33012.1 - 0.26 11.4 7.2 0.4 10.8 7.2 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein GBP_C PF02841.14 KER33012.1 - 0.56 9.6 16.8 1 8.7 16.8 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain EIIBC-GUT_N PF03612.14 KER33012.1 - 0.9 9.3 3.9 1.5 8.5 3.9 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus VIR_N PF15912.5 KER33012.1 - 2 8.0 6.0 3.3 7.2 6.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Connexin PF00029.19 KER33012.1 - 3.5 7.3 11.9 6 6.6 10.8 1.7 2 0 0 2 2 2 0 Connexin SAGA-Tad1 PF12767.7 KER33012.1 - 4.2 7.0 11.7 3.5 7.3 7.9 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit RNA_pol_Rpc4 PF05132.14 KER33012.1 - 8.4 6.8 11.5 15 6.0 11.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 T-box PF00907.22 KER33014.1 - 2.4e-78 262.6 0.0 3.7e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 T-box DUF2756 PF10956.8 KER33015.1 - 0.039 14.5 0.3 0.14 12.7 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) G-7-MTase PF12803.7 KER33016.1 - 0.028 13.6 0.5 0.1 11.7 0.1 1.9 2 0 0 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SDA1 PF05285.12 KER33017.1 - 1.4e-07 31.3 21.7 1.4e-07 31.3 21.7 1.1 1 0 0 1 1 1 1 SDA1 PTPRCAP PF15713.5 KER33017.1 - 0.4 11.0 20.4 0.85 9.9 20.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 KER33017.1 - 0.83 7.8 38.2 1.1 7.4 38.2 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KER33017.1 - 1.8 6.9 28.8 2.4 6.5 28.8 1.2 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 KER33017.1 - 9.1 5.6 34.5 13 5.0 34.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Noc2 PF03715.13 KER33019.1 - 5.1e-72 242.7 2.9 3.4e-46 157.8 1.8 2.5 2 0 0 2 2 2 2 Noc2p family RB_A PF01858.17 KER33019.1 - 0.036 13.9 0.6 0.084 12.7 0.6 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain CN_hydrolase PF00795.22 KER33019.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Nop14 PF04147.12 KER33019.1 - 0.82 7.8 31.2 0.18 10.0 0.2 2.4 2 1 0 2 2 2 0 Nop14-like family Peptidase_C2 PF00648.21 KER33020.1 - 4.9e-117 390.2 0.0 6.3e-117 389.8 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KER33020.1 - 3.4e-42 144.1 0.0 5.4e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF1_GNE PF00736.19 KER33022.1 - 3.6e-34 116.8 1.9 5e-34 116.3 0.3 2.0 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KER33022.1 - 3.9e-13 49.6 6.5 7.9e-13 48.6 6.5 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region DUF1640 PF07798.11 KER33022.1 - 0.0018 18.3 2.3 0.003 17.6 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 KER33022.1 - 0.0048 16.9 0.2 0.0081 16.2 0.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 KER33022.1 - 0.008 16.2 2.3 0.018 15.1 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) FlgN PF05130.12 KER33022.1 - 0.022 15.3 1.3 0.04 14.4 1.3 1.4 1 0 0 1 1 1 0 FlgN protein Prominin PF05478.11 KER33022.1 - 0.032 12.2 1.2 0.044 11.7 1.2 1.1 1 0 0 1 1 1 0 Prominin TRPM_tetra PF16519.5 KER33022.1 - 0.034 14.3 2.8 0.084 13.0 2.8 1.7 1 0 0 1 1 1 0 Tetramerisation domain of TRPM BLOC1_2 PF10046.9 KER33022.1 - 0.038 14.3 4.3 0.052 13.8 2.4 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cupin_4 PF08007.12 KER33022.1 - 0.08 12.4 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Cupin superfamily protein LpxB PF02684.15 KER33022.1 - 0.11 11.3 0.3 0.17 10.7 0.3 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase V_ATPase_I PF01496.19 KER33022.1 - 0.23 9.3 0.3 0.26 9.1 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KER33022.1 - 0.42 11.0 4.5 0.87 10.0 0.7 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 KER33022.1 - 0.93 9.6 5.1 1.8 8.7 5.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 UNC-93 PF05978.16 KER33024.1 - 9.6e-06 25.4 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Arrestin_C PF02752.22 KER33025.1 - 4.6e-16 59.5 0.0 8.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KER33025.1 - 9.6e-13 48.4 0.0 8.2e-05 22.7 0.0 3.2 2 1 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain RNB PF00773.19 KER33026.1 - 4.1e-76 256.4 0.0 6.5e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KER33026.1 - 1.7e-22 79.2 0.0 3.1e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KER33026.1 - 5e-06 26.6 0.0 0.00068 19.8 0.0 2.5 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 KER33026.1 - 5e-05 23.2 0.1 0.00026 20.9 0.1 2.1 1 1 0 1 1 1 1 S1 domain Sulfotransfer_3 PF13469.6 KER33026.1 - 0.011 16.2 0.5 0.028 14.8 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase family Rrp44_CSD1 PF17216.3 KER33026.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Rrp44-like cold shock domain AKAP7_NLS PF10469.9 KER33027.1 - 1.1e-34 120.2 0.0 1.4e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.29 KER33027.1 - 2.4e-09 36.9 0.0 4.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 KH domain Tektin PF03148.14 KER33028.1 - 5.3e-99 331.6 47.2 6.2e-99 331.3 47.2 1.0 1 0 0 1 1 1 1 Tektin family Tropomyosin_1 PF12718.7 KER33028.1 - 0.0035 17.5 2.0 0.0035 17.5 2.0 4.4 3 1 0 4 4 4 1 Tropomyosin like DegQ PF08181.11 KER33028.1 - 0.056 13.6 2.4 0.36 11.0 2.4 2.5 1 0 0 1 1 1 0 DegQ (SacQ) family DUF1664 PF07889.12 KER33028.1 - 0.26 11.3 22.6 0.44 10.6 3.9 4.2 2 2 0 4 4 4 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 KER33028.1 - 0.61 10.5 25.5 0.078 13.4 2.7 4.3 1 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 KER33028.1 - 0.68 10.4 10.0 0.35 11.3 1.4 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KER33028.1 - 5.1 7.8 26.2 1.2 9.8 1.5 4.4 4 0 0 4 4 4 0 SlyX Forkhead PF00250.18 KER33029.1 - 5.7e-37 125.8 0.0 1.3e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain gag-asp_proteas PF13975.6 KER33031.1 - 1.3e-06 28.9 0.0 3.7e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KER33031.1 - 1.4e-06 28.8 0.0 4.5e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KER33031.1 - 0.0034 17.7 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3480 PF11979.8 KER33034.1 - 1.9e-35 122.5 0.0 7e-34 117.3 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3480) SH3_9 PF14604.6 KER33036.1 - 9.1e-27 92.7 0.8 1.6e-14 53.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KER33036.1 - 1.1e-23 82.5 1.4 4.4e-12 45.4 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KER33036.1 - 5.7e-23 80.4 0.7 1.1e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain JHD PF17811.1 KER33036.1 - 0.15 12.6 1.0 0.42 11.2 1.0 1.8 1 0 0 1 1 1 0 Jumonji helical domain DUF5344 PF17279.2 KER33036.1 - 1.6 9.4 6.8 1.6 9.3 2.9 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) TMPIT PF07851.13 KER33036.1 - 2.9 7.1 4.1 5.9 6.0 4.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 KER33036.1 - 4 8.1 9.5 1 10.0 5.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA CAP PF00188.26 KER33038.1 - 5e-13 50.0 2.1 5.7e-12 46.6 2.1 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family HECT PF00632.25 KER33039.1 - 3.8e-56 190.8 0.1 6.3e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KER33039.1 - 4.4e-22 77.8 0.5 6.4e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 KER33039.1 - 3.5e-08 33.7 0.0 9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain UPF0242 PF06785.11 KER33040.1 - 0.00018 21.7 18.6 0.00018 21.7 18.6 3.0 1 1 0 2 2 1 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 KER33040.1 - 0.0006 19.6 8.6 0.028 14.3 0.0 4.8 4 1 0 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 KER33040.1 - 0.00084 18.3 54.4 0.017 14.0 25.1 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein ADIP PF11559.8 KER33040.1 - 0.0041 17.2 13.8 0.0041 17.2 13.8 4.6 1 1 4 5 5 5 3 Afadin- and alpha -actinin-Binding Filament PF00038.21 KER33040.1 - 0.012 15.2 44.2 0.018 14.7 44.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.6 KER33040.1 - 0.019 13.7 46.9 0.061 12.0 15.6 2.1 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.10 KER33040.1 - 0.022 14.9 47.2 0.12 12.6 4.2 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KER33040.1 - 0.022 14.9 4.1 0.022 14.9 4.1 4.4 1 1 3 4 4 4 0 Tropomyosin like Lebercilin PF15619.6 KER33040.1 - 0.048 13.3 60.7 0.15 11.7 6.1 3.3 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease zf-C2H2_9 PF16293.5 KER33040.1 - 0.11 12.4 1.5 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) ATG16 PF08614.11 KER33040.1 - 0.11 12.7 59.2 0.078 13.2 15.2 3.7 1 1 2 3 3 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KER33040.1 - 0.13 11.6 52.3 0.021 14.1 13.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 KER33040.1 - 0.21 12.2 56.1 0.13 12.9 14.5 4.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KER33040.1 - 0.45 10.6 36.5 1.2 9.1 9.4 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KER33040.1 - 0.49 9.8 59.1 2 7.8 33.8 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 KER33040.1 - 0.54 8.1 39.6 1.7 6.5 22.5 2.5 1 1 1 2 2 2 0 Prominin Cep57_CLD_2 PF14197.6 KER33040.1 - 1 9.5 43.8 3 8.0 7.0 4.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Laminin_II PF06009.12 KER33040.1 - 1.1 9.3 35.3 0.23 11.5 4.3 3.5 2 1 1 3 3 3 0 Laminin Domain II HrpB7 PF09486.10 KER33040.1 - 1.1 9.6 39.8 0.81 10.1 17.6 3.8 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Guanylin PF02058.15 KER33040.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.1 3 0 0 3 3 2 0 Guanylin precursor DUF4618 PF15397.6 KER33040.1 - 1.5 8.1 49.3 1.8 7.9 36.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Fez1 PF06818.15 KER33040.1 - 1.5 9.2 56.3 0.98 9.8 15.4 3.1 1 1 2 3 3 3 0 Fez1 MAD PF05557.13 KER33040.1 - 1.6 7.0 60.9 1.6 7.0 39.9 2.8 1 1 2 3 3 3 0 Mitotic checkpoint protein HAP1_N PF04849.13 KER33040.1 - 2.6 7.2 58.9 2.1 7.5 7.9 2.7 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 KER33040.1 - 4.7 6.5 41.3 0.76 9.1 19.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KER33040.1 - 5.2 6.1 49.9 24 3.9 28.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 KER33040.1 - 5.7 7.2 47.8 1.8 8.8 12.3 3.6 1 1 2 3 3 3 0 Flagellar FliJ protein zf-RanBP PF00641.18 KER33041.1 - 2.5e-18 65.1 41.0 2.2e-06 26.8 1.7 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup153 PF08604.10 KER33041.1 - 7e-08 31.7 19.3 7e-08 31.7 19.3 4.7 3 2 0 3 3 3 1 Nucleoporin Nup153-like PX PF00787.24 KER33042.1 - 8.7e-07 28.9 0.1 4.2e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 PX domain LMBR1 PF04791.16 KER33042.1 - 0.094 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSNSD PF12062.8 KER33043.1 - 7.4e-32 110.7 7.7 1.1e-15 57.4 0.0 4.3 3 2 1 4 4 4 4 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 KER33043.1 - 9.7e-15 54.8 0.0 6.5e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KER33043.1 - 1.1e-10 42.3 1.9 0.0037 17.7 0.1 3.4 2 1 1 3 3 3 3 Sulfotransferase family EF-hand_4 PF12763.7 KER33044.1 - 8.7e-08 32.1 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KER33044.1 - 9.6e-05 21.7 0.2 0.00064 19.1 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KER33044.1 - 0.0028 17.5 0.3 0.41 10.7 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KER33044.1 - 0.0049 17.3 0.3 0.066 13.7 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 KER33044.1 - 0.0064 16.3 0.2 0.062 13.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 KER33044.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain RNA_pol_Rpb2_6 PF00562.28 KER33045.1 - 1.9e-119 399.2 0.0 2.7e-119 398.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KER33045.1 - 2.6e-48 164.2 0.0 4.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KER33045.1 - 3.4e-29 101.1 0.5 9.8e-29 99.6 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KER33045.1 - 1.5e-22 79.6 0.5 4.3e-22 78.2 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KER33045.1 - 1.1e-21 76.8 0.1 2.4e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KER33045.1 - 1.6e-18 67.0 0.0 3.5e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 KER33045.1 - 1.2e-12 48.2 0.1 2.9e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L21e PF01157.18 KER33046.1 - 1.9e-45 152.9 4.3 3.7e-45 151.9 4.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L21e Pkinase PF00069.25 KER33047.1 - 9e-71 238.3 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33047.1 - 2.9e-33 115.2 0.1 3.9e-32 111.5 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER33047.1 - 2e-08 33.6 0.6 3.5e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KER33047.1 - 0.00021 20.7 1.1 0.00026 20.4 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER33047.1 - 0.0019 17.6 0.1 0.0056 16.0 0.0 1.8 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KER33047.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KER33047.1 - 0.028 14.3 0.2 0.44 10.4 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 KER33047.1 - 0.059 13.0 0.1 4.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CENP-B_dimeris PF09026.10 KER33048.1 - 0.15 12.5 11.1 0.28 11.6 11.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 KER33048.1 - 0.24 11.0 5.9 3.3 7.3 2.7 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KER33048.1 - 1 8.6 9.3 1.9 7.8 9.3 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KER33048.1 - 7.2 4.6 7.9 11 3.9 7.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi HLH PF00010.26 KER33049.1 - 1.3e-12 47.5 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4675 PF15720.5 KER33049.1 - 0.14 11.9 4.6 0.37 10.6 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4675) Ribosomal_L18A PF01775.17 KER33050.1 - 1e-46 158.0 0.6 1.3e-46 157.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A LRR_6 PF13516.6 KER33052.1 - 7e-21 72.5 12.0 0.0042 17.0 0.0 9.3 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 KER33052.1 - 2.9e-05 24.3 7.6 0.033 14.6 0.0 5.6 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER33052.1 - 0.0047 17.3 0.6 57 4.8 0.0 6.7 10 0 0 10 10 10 1 Leucine Rich Repeat zf-C2H2_2 PF12756.7 KER33054.1 - 9.8e-05 22.6 12.1 0.077 13.3 1.8 3.5 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KER33054.1 - 0.00034 20.9 15.1 0.044 14.3 0.5 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2HE PF16278.5 KER33054.1 - 0.087 13.3 1.9 0.31 11.5 0.2 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 KER33054.1 - 0.7 10.9 15.0 0.72 10.8 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-FCS PF06467.14 KER33054.1 - 2.8 8.0 5.0 8.2 6.5 1.6 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C2 PF00168.30 KER33058.1 - 9.2e-37 125.5 0.2 5.4e-17 62.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 KER33058.1 - 5.9e-16 58.8 3.3 1.2e-15 57.8 3.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 KER33058.1 - 0.24 11.3 9.5 0.69 9.8 9.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CRD PF17979.1 KER33058.1 - 0.31 11.1 4.7 0.78 9.8 4.7 1.6 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 KER33058.1 - 0.35 11.0 4.0 0.9 9.7 4.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 KER33058.1 - 0.5 10.6 6.2 1.5 9.1 6.2 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KER33058.1 - 0.63 9.9 9.6 1.8 8.5 9.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER33058.1 - 2.2 8.7 10.9 5.3 7.5 10.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 KER33058.1 - 5.5 7.2 7.0 14 5.9 7.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ank_2 PF12796.7 KER33059.1 - 2.6e-19 69.6 7.8 3e-10 40.6 1.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER33059.1 - 2.2e-14 53.3 5.9 6.3e-09 35.9 0.3 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER33059.1 - 1.9e-12 47.4 4.7 4e-05 24.1 0.2 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER33059.1 - 2.9e-12 45.6 1.7 0.05 14.2 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KER33059.1 - 8.2e-10 38.7 5.2 0.086 13.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Peptidase_M24 PF00557.24 KER33060.1 - 9.8e-32 110.3 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Nucleoporin_FG2 PF15967.5 KER33060.1 - 0.00035 19.3 2.2 0.0012 17.5 2.2 1.7 1 1 0 1 1 1 1 Nucleoporin FG repeated region Radical_SAM PF04055.21 KER33061.1 - 3.4e-32 112.1 0.0 7.2e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Complex1_LYR PF05347.15 KER33062.1 - 0.00017 21.6 1.7 0.00042 20.3 1.7 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Med26 PF08711.11 KER33063.1 - 5.2e-05 23.2 0.2 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Scs3p PF10261.9 KER33066.1 - 2.8e-27 95.8 14.8 6.8e-27 94.5 14.8 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM I-set PF07679.16 KER33067.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 KER33067.1 - 3.2e-06 27.2 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 KER33067.1 - 1.8e-05 25.2 0.1 3.2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 KER33067.1 - 3.9e-05 23.8 0.0 6.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.6 KER33067.1 - 0.016 15.5 0.1 0.031 14.6 0.0 1.6 1 1 1 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 KER33067.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Pox_C7_F8A PF03287.14 KER33067.1 - 0.041 13.9 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C7/F8A protein Izumo-Ig PF16706.5 KER33067.1 - 0.059 13.4 0.0 0.12 12.5 0.0 1.6 1 1 1 2 2 2 0 Izumo-like Immunoglobulin domain UDG PF03167.19 KER33068.1 - 3.4e-05 23.9 2.2 0.18 11.8 0.2 2.7 2 1 0 2 2 2 2 Uracil DNA glycosylase superfamily zinc_ribbon_6 PF14599.6 KER33068.1 - 0.0027 17.7 0.4 4.3 7.4 0.0 2.9 2 0 0 2 2 2 2 Zinc-ribbon Vpu PF00558.19 KER33068.1 - 0.009 15.8 0.0 8.2 6.3 0.0 2.8 2 0 0 2 2 2 2 Vpu protein zf-ZPR1 PF03367.13 KER33068.1 - 0.0094 15.8 2.2 6.1 6.7 0.0 3.5 3 0 0 3 3 3 2 ZPR1 zinc-finger domain zf_UBZ PF18439.1 KER33068.1 - 0.012 15.2 3.3 2.9 7.6 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SpvB PF03534.13 KER33068.1 - 0.016 14.4 1.8 2.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein DUF2197 PF09963.9 KER33068.1 - 0.021 15.1 3.3 6.3 7.1 0.2 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF5338 PF17273.2 KER33068.1 - 0.026 14.6 0.0 16 5.6 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5338) Ribosomal_S20p PF01649.18 KER33068.1 - 0.039 14.6 2.2 17 6.1 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein S20 Tubulin_C PF03953.17 KER33068.1 - 0.08 13.1 0.2 24 5.1 0.0 2.7 2 0 0 2 2 2 0 Tubulin C-terminal domain YokU PF14122.6 KER33068.1 - 0.13 12.2 5.0 8 6.5 0.1 3.2 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin UME PF08064.13 KER33068.1 - 0.16 11.9 1.1 3.9 7.4 0.1 3.0 4 0 0 4 4 4 0 UME (NUC010) domain zf-dskA_traR PF01258.17 KER33068.1 - 0.18 11.8 7.3 8.2 6.5 0.0 3.8 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger DUF5374 PF17344.2 KER33068.1 - 0.3 11.0 2.8 20 5.2 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5374) PDDEXK_5 PF11645.8 KER33068.1 - 1.2 9.1 6.2 13 5.7 0.2 3.1 3 0 0 3 3 3 0 PD-(D/E)XK endonuclease PDCD9 PF07147.12 KER33072.1 - 5.3e-33 114.9 0.0 1.6e-18 67.2 0.0 3.7 2 1 1 3 3 3 3 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF5114 PF17141.4 KER33073.1 - 0.076 13.5 0.3 0.087 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) His_Phos_2 PF00328.22 KER33074.1 - 1.6e-107 360.2 0.0 2.1e-107 359.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 KER33074.1 - 1.5e-05 24.7 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain IMD PF08397.11 KER33075.1 - 8.2e-15 54.8 0.1 2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 IRSp53/MIM homology domain RVT_1 PF00078.27 KER33075.1 - 6.2e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FH2 PF02181.23 KER33077.1 - 2.4e-67 227.7 2.4 3.6e-66 223.8 2.4 2.4 1 1 0 1 1 1 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 KER33077.1 - 4.6e-08 33.4 0.1 1.7e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain DUF2039 PF10217.9 KER33078.1 - 0.033 14.5 0.9 0.067 13.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) SPRY PF00622.28 KER33081.1 - 6.5e-13 48.9 0.3 2e-12 47.3 0.3 2.0 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KER33081.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KER33081.1 - 0.23 11.5 0.1 0.71 9.9 0.1 1.8 1 0 0 1 1 1 0 LisH PHD PF00628.29 KER33084.1 - 4.3e-05 23.3 5.0 4.3e-05 23.3 5.0 1.8 2 0 0 2 2 2 1 PHD-finger VIR_N PF15912.5 KER33086.1 - 3.9e-26 92.2 0.5 5.2e-26 91.8 0.5 1.1 1 0 0 1 1 1 1 Virilizer, N-terminal CBM_21 PF03370.13 KER33088.1 - 2.9e-27 95.1 0.0 5.8e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KER33088.1 - 7.7e-13 48.8 0.2 3e-12 46.9 0.2 2.0 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) UCH PF00443.29 KER33092.1 - 1.7e-39 135.8 0.0 4.7e-39 134.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER33092.1 - 2.2e-25 89.9 0.0 9.6e-25 87.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KER33092.1 - 0.00057 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Aminotran_1_2 PF00155.21 KER33096.1 - 2e-35 122.7 0.0 2.5e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Limkain-b1 PF11608.8 KER33096.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Beta_elim_lyase PF01212.21 KER33096.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 KER33096.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase NUDE_C PF04880.13 KER33098.1 - 1.6e-17 64.5 0.2 1.6e-17 64.5 0.2 2.7 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region DUF2353 PF09789.9 KER33098.1 - 8.8e-05 22.0 11.2 8.8e-05 22.0 11.2 2.0 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DUF3251 PF11622.8 KER33098.1 - 0.023 14.3 2.3 0.087 12.5 2.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) Ctf8 PF09696.10 KER33098.1 - 0.23 11.8 0.2 0.23 11.8 0.2 2.1 1 1 1 2 2 2 0 Ctf8 Fib_alpha PF08702.10 KER33098.1 - 0.28 11.3 10.1 0.67 10.1 10.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KER33098.1 - 0.9 10.2 20.5 6.2 7.5 9.5 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 KER33098.1 - 1.8 7.4 27.4 3 6.6 27.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KER33098.1 - 1.9 8.3 17.8 1.1 9.1 10.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF883 PF05957.13 KER33098.1 - 2.1 9.0 7.9 2.2 9.0 3.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GAS PF13851.6 KER33098.1 - 2.1 7.6 26.0 2.9 7.2 15.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KER33098.1 - 2.2 8.3 30.1 6.3 6.8 3.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KER33098.1 - 2.6 8.1 32.5 2.2 8.4 1.9 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 KER33098.1 - 2.7 7.3 12.9 1.1 8.5 8.5 1.9 1 1 1 2 2 2 0 FAM76 protein DUF4337 PF14235.6 KER33098.1 - 3 7.9 12.7 0.66 10.1 6.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) HAP1_N PF04849.13 KER33098.1 - 5.1 6.2 29.7 11 5.1 29.7 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region KASH_CCD PF14662.6 KER33098.1 - 6.3 6.6 31.5 1.5e+02 2.1 30.7 2.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KER33098.1 - 8.5 6.5 30.2 3.6 7.8 25.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) adh_short PF00106.25 KER33099.1 - 4.7e-42 143.7 0.0 5.9e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KER33099.1 - 1e-24 87.4 0.0 1.3e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KER33099.1 - 9e-08 32.2 0.0 2.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KER33099.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KER33099.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KER33099.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KER33099.1 - 0.028 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KER33099.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FERM_M PF00373.18 KER33100.1 - 2.6e-26 92.3 0.1 2.6e-26 92.3 0.1 2.8 3 1 0 3 3 3 1 FERM central domain FERM_C PF09380.10 KER33100.1 - 1.9e-15 57.0 1.0 7.1e-11 42.4 0.7 3.1 2 1 0 2 2 2 2 FERM C-terminal PH-like domain Lipoprotein_7 PF01540.16 KER33100.1 - 0.019 14.3 2.4 0.028 13.7 2.4 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein DUF724 PF05266.14 KER33100.1 - 1.8 8.3 14.8 0.43 10.4 7.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KER33100.1 - 5.6 4.8 11.5 9 4.1 11.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KER33100.1 - 7.6 6.6 15.6 19 5.3 15.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2514 PF10721.9 KER33100.1 - 9.2 6.3 10.2 7.3 6.6 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) HEAT PF02985.22 KER33101.1 - 1.1e-45 149.7 40.1 0.0014 18.7 0.1 17.1 17 0 0 17 17 17 11 HEAT repeat HEAT_2 PF13646.6 KER33101.1 - 5.3e-45 151.7 16.2 8.1e-12 45.4 0.0 8.7 4 3 5 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KER33101.1 - 3.7e-15 56.3 0.1 0.014 16.0 0.0 7.7 6 3 2 8 8 8 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KER33101.1 - 1.4e-11 44.4 1.4 0.0047 16.5 0.0 6.8 3 2 3 7 7 7 3 CLASP N terminal Adaptin_N PF01602.20 KER33101.1 - 8.5e-09 34.5 7.7 0.024 13.2 0.5 5.0 4 1 1 5 5 5 4 Adaptin N terminal region Cnd1 PF12717.7 KER33101.1 - 2.7e-08 34.0 11.1 0.00093 19.3 0.1 6.9 4 2 4 8 8 8 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KER33101.1 - 3.4e-05 24.0 5.9 1.1 9.4 0.0 5.9 5 3 2 8 8 7 2 Required for nuclear transport of RNA pol II C-terminus 1 HTH_5 PF01022.20 KER33101.1 - 0.016 15.0 0.6 10 6.1 0.1 2.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TAF6_C PF07571.13 KER33101.1 - 0.051 13.9 1.2 1.2e+02 3.0 0.0 4.8 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain DUF3700 PF12481.8 KER33101.1 - 0.062 12.7 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Aluminium induced protein MMS19_N PF14500.6 KER33101.1 - 0.12 12.0 1.1 28 4.2 0.0 4.5 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Fiji_64_capsid PF05880.11 KER33101.1 - 0.17 10.5 0.2 9.5 4.7 0.1 2.1 2 0 0 2 2 2 0 Fijivirus 64 kDa capsid protein IFRD PF05004.13 KER33101.1 - 0.17 11.0 0.0 0.87 8.6 0.0 2.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KER33101.1 - 0.29 11.7 24.7 11 6.6 3.0 8.5 10 2 1 11 11 10 0 HEAT-like repeat RasGEF_N_2 PF14663.6 KER33101.1 - 0.38 11.2 4.8 15 6.1 0.2 5.1 4 2 1 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PHF5 PF03660.14 KER33104.1 - 1.8e-39 134.2 13.9 3.4e-39 133.2 13.9 1.4 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KER33104.1 - 4.4 5.0 8.6 5.7 4.7 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Btz PF09405.10 KER33105.1 - 3.6e-15 56.4 3.9 3.6e-15 56.4 3.9 2.5 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding BRE1 PF08647.11 KER33107.1 - 1.9e-11 43.9 15.2 1.9e-11 43.9 15.2 10.1 6 3 4 10 10 10 4 BRE1 E3 ubiquitin ligase Tae4 PF14113.6 KER33107.1 - 1.1 9.5 7.0 0.46 10.7 1.6 3.0 1 1 1 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 TH1 PF04858.13 KER33110.1 - 2.1e-41 142.3 0.2 6.9e-19 67.9 0.0 3.0 2 1 1 3 3 3 3 TH1 protein DUF667 PF05018.13 KER33112.1 - 2.1e-92 308.0 1.4 2.3e-92 307.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Innexin PF00876.18 KER33113.1 - 1.6e-126 422.3 10.9 1.9e-126 422.1 10.9 1.0 1 0 0 1 1 1 1 Innexin Formin_GBD_N PF18382.1 KER33117.1 - 0.082 13.4 2.7 0.12 12.8 1.1 2.0 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain COesterase PF00135.28 KER33117.1 - 0.69 8.7 4.1 0.82 8.5 4.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family Ets PF00178.22 KER33120.1 - 4.3e-35 120.0 0.3 9.1e-35 119.0 0.3 1.6 1 0 0 1 1 1 1 Ets-domain Branch PF02485.21 KER33122.1 - 2.2e-30 106.0 0.0 3.3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Xylo_C PF12529.8 KER33122.1 - 6.8e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal WSC PF01822.19 KER33122.1 - 0.00015 21.9 0.2 0.00037 20.6 0.2 1.7 1 0 0 1 1 1 1 WSC domain SHIPPO-rpt PF07004.12 KER33123.1 - 1.1e-09 38.7 3.3 1.3 10.0 0.1 5.9 6 0 0 6 6 6 4 Sperm-tail PG-rich repeat PDZ PF00595.24 KER33125.1 - 5e-11 42.8 0.0 7.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 KER33125.1 - 2.2e-08 34.2 3.9 3.4e-08 33.6 3.9 1.3 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 KER33125.1 - 2.1e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 KER33125.1 - 0.00019 22.4 0.1 0.00069 20.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 KER33125.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Y_phosphatase PF00102.27 KER33126.1 - 4.1e-158 524.0 0.4 7.1e-81 271.2 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 KER33126.1 - 1.9e-27 95.4 1.8 5.1e-14 52.4 0.2 5.5 5 1 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.20 KER33126.1 - 1.9e-08 34.2 0.0 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER33126.1 - 2.3e-06 27.8 0.0 0.088 12.8 0.0 2.6 3 0 0 3 3 3 2 Tyrosine phosphatase family Pur_ac_phosph_N PF16656.5 KER33126.1 - 8.6e-05 23.0 2.8 0.34 11.5 0.2 3.3 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain PTPlike_phytase PF14566.6 KER33126.1 - 0.00039 20.6 0.4 0.24 11.5 0.1 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate fn3_4 PF16794.5 KER33126.1 - 0.0028 17.5 0.0 0.2 11.6 0.0 3.1 2 0 0 2 2 2 1 Fibronectin-III type domain Adeno_E3_CR2 PF02439.15 KER33126.1 - 0.52 10.1 4.0 1.3 8.9 4.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 fn3 PF00041.21 KER33127.1 - 3.5e-21 75.3 0.3 2e-13 50.5 0.0 3.1 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER33127.1 - 1.4e-06 28.8 0.0 0.039 14.5 0.0 2.5 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF1582 PF07621.11 KER33127.1 - 0.054 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Ig_3 PF13927.6 KER33129.1 - 7.3e-34 116.2 0.2 1.2e-13 51.4 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 KER33129.1 - 2.2e-32 111.0 0.0 4.2e-14 52.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 KER33129.1 - 2.5e-18 66.2 0.0 6e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KER33129.1 - 7.5e-16 58.1 0.1 5e-08 33.0 0.0 3.8 3 2 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 KER33129.1 - 9.7e-09 35.5 0.5 3.1e-08 33.8 0.2 2.1 2 1 0 2 2 2 1 Fibronectin type III domain V-set PF07686.17 KER33129.1 - 7.7e-07 29.3 0.8 0.12 12.6 0.2 4.4 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER33129.1 - 6.6e-05 22.9 0.2 0.067 13.3 0.0 3.3 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 KER33129.1 - 0.04 14.3 0.0 3.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pur_ac_phosph_N PF16656.5 KER33129.1 - 0.11 13.0 0.1 0.33 11.6 0.1 1.8 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain WD40 PF00400.32 KER33130.1 - 3.3e-22 78.4 11.9 1.6e-10 41.4 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33130.1 - 4.6e-07 30.0 0.0 0.047 14.0 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KER33130.1 - 0.0007 18.0 0.0 0.034 12.5 0.0 2.0 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KER33130.1 - 0.0046 16.0 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KER33130.1 - 0.017 15.6 0.0 1.4 9.5 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain MarB PF13999.6 KER33132.1 - 0.076 12.9 0.0 0.32 10.9 0.0 2.1 1 0 0 1 1 1 0 MarB protein AAA PF00004.29 KER33135.1 - 0.051 14.0 0.4 0.42 11.0 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) JAKMIP_CC3 PF16034.5 KER33135.1 - 0.17 11.8 8.4 6.5 6.6 0.0 3.3 3 1 1 4 4 4 0 JAKMIP CC3 domain MPS-4 PF17523.2 KER33136.1 - 0.015 15.4 0.7 0.017 15.3 0.7 1.1 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 NDUF_B5 PF09781.9 KER33137.1 - 1.4e-42 145.4 0.1 3.6e-42 144.1 0.0 1.7 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit NPDC1 PF06809.11 KER33141.1 - 4.6e-23 81.8 0.1 1.5e-22 80.1 0.3 1.6 2 0 0 2 2 2 1 Neural proliferation differentiation control-1 protein (NPDC1) GST_C_3 PF14497.6 KER33142.1 - 4.4e-13 49.3 0.0 7.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER33142.1 - 8.9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KER33142.1 - 0.0093 16.4 0.0 0.045 14.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KER33142.1 - 0.059 13.7 0.0 0.21 11.9 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KER33143.1 - 3.4e-14 52.8 0.0 5.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER33143.1 - 3.9e-09 36.6 0.0 7.8e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KER33143.1 - 5.6e-05 23.1 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER33143.1 - 0.005 17.2 0.0 0.024 15.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KER33143.1 - 0.0063 16.9 0.0 0.019 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KER33144.1 - 2.2e-16 59.8 0.0 3.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KER33144.1 - 1.2e-09 38.2 0.0 2.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KER33144.1 - 6e-06 26.5 0.2 3.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KER33144.1 - 0.00044 20.5 0.0 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KER33144.1 - 0.0037 17.3 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-HC5HC2H PF13771.6 KER33145.1 - 0.11 12.8 7.0 0.042 14.1 3.3 2.3 3 0 0 3 3 3 0 PHD-like zinc-binding domain UvrB PF12344.8 KER33145.1 - 0.14 12.0 0.7 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Ultra-violet resistance protein B Zf_RING PF16744.5 KER33145.1 - 0.58 10.3 3.9 3.7 7.7 1.8 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 KER33145.1 - 0.74 9.8 12.7 0.12 12.3 7.0 2.7 2 1 1 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KER33145.1 - 2.4 8.4 5.2 7.7 6.7 5.2 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-MYND PF01753.18 KER33146.1 - 0.00039 20.4 14.1 0.0007 19.6 14.1 1.4 1 0 0 1 1 1 1 MYND finger Dpy-30 PF05186.13 KER33149.1 - 3.2e-15 55.5 0.7 4.9e-15 55.0 0.1 1.6 2 0 0 2 2 2 1 Dpy-30 motif DUF2465 PF10239.9 KER33150.1 - 2.7e-67 227.3 0.0 3.3e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Amidinotransf PF02274.17 KER33151.1 - 3.5e-07 29.6 0.1 1.7e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Amidinotransferase TPR_11 PF13414.6 KER33152.1 - 4e-16 58.4 4.6 8.7e-10 38.1 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 KER33152.1 - 5.9e-15 54.4 0.3 0.00024 20.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KER33152.1 - 2.2e-09 36.7 0.2 0.17 12.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KER33152.1 - 5.2e-09 35.9 1.2 0.015 15.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KER33152.1 - 3.3e-08 33.6 4.1 5.4e-07 29.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER33152.1 - 1.6e-07 30.9 1.0 0.019 15.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KER33152.1 - 1.7e-07 31.8 4.6 0.0005 20.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER33152.1 - 5.4e-07 29.9 5.4 0.0042 17.8 0.1 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER33152.1 - 3.5e-06 27.4 1.2 0.091 13.3 0.1 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER33152.1 - 0.00015 22.0 2.4 0.0074 16.6 1.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat S1 PF00575.23 KER33152.1 - 0.0017 18.7 0.0 0.0051 17.1 0.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain NARP1 PF12569.8 KER33152.1 - 0.038 12.9 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RhoGEF PF00621.20 KER33155.1 - 6.7e-25 88.4 1.6 1.2e-24 87.5 1.6 1.4 1 0 0 1 1 1 1 RhoGEF domain TGS PF02824.21 KER33158.1 - 3e-05 24.0 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain SURF1 PF02104.15 KER33159.1 - 2e-34 119.4 0.0 2.9e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 SURF1 family RVT_1 PF00078.27 KER33161.1 - 1.8e-08 34.2 0.0 2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MG2 PF01835.19 KER33163.1 - 5.1e-08 33.3 0.0 1.4e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 MG2 domain MG3 PF17791.1 KER33163.1 - 0.022 15.0 0.0 0.093 13.0 0.0 2.1 2 0 0 2 2 2 0 Macroglobulin domain MG3 Pkinase PF00069.25 KER33164.1 - 2.1e-62 210.9 0.0 2.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33164.1 - 5e-37 127.6 0.0 6.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER33164.1 - 0.0033 16.4 0.2 0.0047 15.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER33164.1 - 0.0052 16.1 0.0 0.096 12.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER33164.1 - 0.037 12.8 0.0 0.087 11.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase DUF3437 PF11919.8 KER33164.1 - 0.054 13.4 0.2 0.094 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Pellino PF04710.14 KER33165.1 - 8.7e-89 298.0 0.0 4.5e-85 285.8 0.0 2.8 1 1 1 2 2 2 2 Pellino Exo_endo_phos PF03372.23 KER33165.1 - 0.0048 16.5 0.0 0.013 15.1 0.0 1.6 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Prok-RING_4 PF14447.6 KER33165.1 - 0.53 10.2 9.3 14 5.6 0.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KER33165.1 - 1.2 9.1 9.2 3.3 7.6 2.3 3.1 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER33165.1 - 2 8.8 9.4 1.9 8.9 0.4 2.9 2 0 0 2 2 2 0 Ring finger domain zf-C2H2 PF00096.26 KER33166.1 - 2.4e-11 43.4 27.1 3.8e-06 27.0 3.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER33166.1 - 8.6e-11 41.8 18.1 4e-07 30.2 1.7 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER33166.1 - 9e-09 35.5 26.6 0.0015 19.2 2.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KER33166.1 - 1.8e-05 24.4 1.7 1.8e-05 24.4 1.7 4.6 6 0 0 6 6 5 1 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 KER33166.1 - 0.013 15.6 0.4 0.031 14.4 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger FYVE PF01363.21 KER33166.1 - 0.34 11.1 19.4 0.074 13.2 5.5 2.7 3 0 0 3 3 2 0 FYVE zinc finger HNH PF01844.23 KER33166.1 - 0.87 9.8 7.3 35 4.7 0.1 3.4 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_2 PF12756.7 KER33166.1 - 2.3 8.6 18.0 50 4.3 0.0 4.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KER33166.1 - 2.6 8.4 22.2 0.47 10.8 0.4 4.4 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KER33166.1 - 3 7.7 8.4 1.1 9.1 1.0 2.6 2 0 0 2 2 2 0 U1 zinc finger OrsD PF12013.8 KER33166.1 - 4.2 7.8 9.3 4.9 7.6 1.5 2.9 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-TAZ PF02135.16 KER33166.1 - 4.6 7.8 12.5 1.6 9.2 9.0 2.0 1 1 0 1 1 1 0 TAZ zinc finger PyrI_C PF02748.15 KER33166.1 - 5.5 7.0 11.2 5.8 6.9 0.5 3.7 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3268 PF11672.8 KER33166.1 - 5.6 7.3 10.4 0.47 10.8 4.4 2.1 1 1 0 2 2 2 0 zinc-finger-containing domain RT_RNaseH PF17917.1 KER33170.1 - 0.0027 18.0 0.0 0.0066 16.7 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glucosamine_iso PF01182.20 KER33171.1 - 8e-65 218.9 0.0 9e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Radial_spoke PF04712.12 KER33172.1 - 2.3e-119 399.6 0.0 2.3e-119 399.6 0.0 1.7 2 0 0 2 2 2 1 Radial spokehead-like protein PGA2 PF07543.12 KER33172.1 - 5.3 7.0 7.2 2.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 ABC-3 PF00950.17 KER33173.1 - 0.0023 17.5 2.5 0.049 13.1 0.1 2.2 1 1 1 2 2 2 1 ABC 3 transport family Saf_2TM PF18303.1 KER33173.1 - 0.0024 17.5 2.3 0.28 10.8 0.0 2.6 2 1 1 3 3 3 2 SAVED-fused 2TM effector domain Claudin_2 PF13903.6 KER33173.1 - 1.4 8.6 10.8 5.2e+02 0.3 10.7 3.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Defensin_propep PF00879.18 KER33173.1 - 2.7 8.3 8.3 4.8 7.5 0.4 2.7 2 0 0 2 2 2 0 Defensin propeptide Ost5 PF05251.12 KER33173.1 - 6 7.2 12.7 9.2 6.6 2.4 2.8 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 DUF4064 PF13273.6 KER33173.1 - 7.6 6.9 12.0 1.2e+02 3.0 2.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3955 PF13127.6 KER33173.1 - 9.5 6.1 15.2 7 6.6 1.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) BAT2_N PF07001.11 KER33174.1 - 7.9e-20 72.1 4.4 7.9e-20 72.1 4.4 10.6 9 4 3 13 13 13 1 BAT2 N-terminus Syntaxin-5_N PF11416.8 KER33174.1 - 0.017 14.3 1.6 0.042 13.1 1.6 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain DSPc PF00782.20 KER33176.1 - 1.4e-20 73.5 0.0 2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.14 KER33176.1 - 0.02 15.1 0.3 0.045 14.0 0.3 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase PF00102.27 KER33176.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glyco_hydro_19 PF00182.19 KER33178.1 - 2.1e-30 106.3 0.4 5.5e-29 101.7 0.4 2.1 1 1 0 1 1 1 1 Chitinase class I Flavodoxin_1 PF00258.25 KER33179.1 - 1.6e-18 67.3 0.0 2.1e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin REV1_C PF16727.5 KER33180.1 - 0.065 13.6 1.7 0.89 10.0 1.4 2.3 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain zf-CCCH_2 PF14608.6 KER33181.1 - 0.12 12.9 1.7 0.23 12.0 1.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KER33181.1 - 3.1 7.8 9.6 0.9 9.5 4.8 2.4 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF229 PF02995.17 KER33188.1 - 7.2e-93 311.9 0.0 9e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 KER33188.1 - 0.055 12.9 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Sulfatase MotB_plug PF13677.6 KER33188.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Phosphorylase PF00343.20 KER33190.1 - 0 1130.3 0.0 9.6e-199 662.1 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate phosphorylase KH_6 PF15985.5 KER33193.1 - 1.6e-10 41.1 0.0 3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KER33193.1 - 0.13 12.2 0.2 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain Ras PF00071.22 KER33195.1 - 7.5e-25 87.4 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER33195.1 - 4.1e-08 33.4 0.0 7.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER33195.1 - 0.049 13.1 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family TRAP-gamma PF07074.12 KER33196.1 - 4.8e-50 169.4 1.6 6.7e-50 169.0 1.6 1.2 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) NUDIX PF00293.28 KER33197.1 - 3.3e-12 46.6 0.0 6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4715 PF15835.5 KER33200.1 - 2.1 8.4 10.4 0.52 10.4 5.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) Folliculin PF11704.8 KER33201.1 - 2.2e-44 151.6 0.0 3.5e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 KER33201.1 - 8.8e-43 146.6 0.0 1.3e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Folliculin C-terminal domain PhoLip_ATPase_N PF16209.5 KER33202.1 - 2.9e-13 49.3 2.9 1.1e-12 47.4 2.9 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KER33202.1 - 2.5e-07 30.7 0.2 7.4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KER33202.1 - 0.00061 19.4 0.3 0.0042 16.6 0.3 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KER33202.1 - 0.0035 17.6 0.3 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Toxin_10 PF05431.11 KER33202.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 TatC PF00902.18 KER33202.1 - 7.8 6.3 11.4 0.096 12.5 0.9 2.4 3 0 0 3 3 3 0 Sec-independent protein translocase protein (TatC) PhoLip_ATPase_C PF16212.5 KER33203.1 - 1.1e-46 159.7 22.7 1.5e-46 159.2 22.7 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_C PF16212.5 KER33204.1 - 1e-38 133.6 52.8 1.9e-25 90.1 7.9 6.7 5 2 1 6 6 6 3 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KER33204.1 - 9.5e-12 44.4 4.0 2.6e-11 43.0 4.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KER33204.1 - 2.2e-10 41.2 1.3 6.6e-06 26.6 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER33204.1 - 3.3e-06 27.1 0.0 0.00022 21.2 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KER33204.1 - 0.00036 20.1 0.0 0.0024 17.4 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KER33204.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PrgI PF12666.7 KER33204.1 - 6.5 7.5 12.0 31 5.4 0.2 4.4 3 1 1 4 4 4 0 PrgI family protein Branch PF02485.21 KER33206.1 - 2.3e-28 99.3 0.0 2.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 KER33207.1 - 1.6e-24 85.6 5.7 7.2e-06 26.6 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33207.1 - 1.8e-10 41.0 0.0 0.0053 17.0 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 KER33207.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain WD40_like PF17005.5 KER33207.1 - 0.027 13.8 0.0 6.3 6.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 KER33207.1 - 0.038 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Ras PF00071.22 KER33211.1 - 2.9e-48 163.5 0.1 5.5e-48 162.6 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER33211.1 - 3e-22 79.1 0.0 6.9e-22 77.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER33211.1 - 5.3e-09 35.8 0.1 7.8e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER33211.1 - 0.00061 19.4 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KER33211.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TF_Zn_Ribbon PF08271.12 KER33214.1 - 3.4e-10 39.3 1.5 6.4e-10 38.4 1.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 KER33214.1 - 2.3e-06 27.6 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat CobT_C PF11775.8 KER33214.1 - 0.11 12.1 0.2 7.2 6.2 0.0 2.6 1 1 2 3 3 3 0 Cobalamin biosynthesis protein CobT VWA domain Branch PF02485.21 KER33215.1 - 3e-07 30.2 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Pkinase_Tyr PF07714.17 KER33220.1 - 2.5e-45 154.8 0.0 4e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER33220.1 - 7.6e-30 104.2 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 KER33220.1 - 2.2e-16 59.9 0.7 7.1e-16 58.2 0.7 1.8 1 1 0 1 1 1 1 Receptor family ligand binding region Kinase-like PF14531.6 KER33220.1 - 0.033 13.5 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RNB PF00773.19 KER33220.1 - 0.047 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 RNB domain FtsX_ECD PF18075.1 KER33223.1 - 0.0097 16.5 4.6 3.2 8.4 0.1 3.2 2 0 0 2 2 2 2 FtsX extracellular domain APG6_N PF17675.1 KER33223.1 - 0.013 16.0 9.7 0.013 16.0 9.7 4.6 2 1 2 4 4 4 0 Apg6 coiled-coil region HALZ PF02183.18 KER33223.1 - 3.5 7.9 11.1 0.12 12.6 1.8 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Scaffolding_pro PF11418.8 KER33223.1 - 9.1 6.9 8.8 2.3 8.8 1.6 3.4 3 1 0 3 3 3 0 Phi29 scaffolding protein Cu2_monoox_C PF03712.15 KER33225.1 - 3.5e-60 202.0 0.0 5.8e-60 201.3 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 KER33225.1 - 1.4e-42 145.0 0.1 3.4e-42 143.8 0.1 1.7 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain I-set PF07679.16 KER33226.1 - 0 1185.4 0.0 1.3e-17 63.6 0.0 29.0 29 0 0 29 29 29 27 Immunoglobulin I-set domain Ig_3 PF13927.6 KER33226.1 - 0 1113.3 38.0 1.9e-17 63.6 0.0 28.6 28 0 0 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 KER33226.1 - 8.6e-235 759.8 30.9 8.8e-11 42.0 0.0 29.9 30 1 1 31 31 29 28 Immunoglobulin domain ig PF00047.25 KER33226.1 - 5.2e-209 677.1 5.3 1.8e-09 37.6 0.0 28.3 28 0 0 28 28 28 26 Immunoglobulin domain V-set PF07686.17 KER33226.1 - 2.5e-87 288.2 30.7 4.9e-06 26.7 0.0 34.1 25 10 3 28 28 28 17 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER33226.1 - 5.6e-68 225.0 39.7 0.0027 17.7 0.0 25.8 26 0 0 26 26 26 18 CD80-like C2-set immunoglobulin domain TSP_1 PF00090.19 KER33226.1 - 4e-54 180.6 90.1 4.5e-11 42.8 7.9 7.8 6 0 0 6 6 6 5 Thrombospondin type 1 domain EGF_CA PF07645.15 KER33226.1 - 3e-41 139.3 112.3 1.2e-08 35.0 3.6 10.0 9 0 0 9 9 8 7 Calcium-binding EGF domain Ig_6 PF18452.1 KER33226.1 - 2.4e-38 129.5 0.6 0.03 13.9 0.0 22.9 26 0 0 26 26 26 5 Immunoglobulin domain Izumo-Ig PF16706.5 KER33226.1 - 7.6e-27 93.2 4.2 0.16 12.1 0.0 18.7 21 0 0 21 21 21 4 Izumo-like Immunoglobulin domain cEGF PF12662.7 KER33226.1 - 1.9e-26 91.6 54.4 2.6e-10 40.0 2.2 9.0 8 0 0 8 8 8 6 Complement Clr-like EGF-like C1-set PF07654.15 KER33226.1 - 9.7e-20 70.8 2.7 7 7.1 0.0 17.7 20 0 0 20 20 18 1 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 KER33226.1 - 2.7e-17 62.3 2.7 0.39 10.5 0.1 14.4 16 0 0 16 16 16 2 Adenovirus E3 region protein CR1 BiPBP_C PF06832.12 KER33226.1 - 6.5e-14 51.7 0.0 2 8.5 0.0 11.0 10 1 0 10 10 10 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 KER33226.1 - 5.1e-12 46.0 0.0 2 8.6 0.0 11.8 14 1 1 15 15 12 2 Natural killer cell receptor 2B4 FXa_inhibition PF14670.6 KER33226.1 - 1.4e-10 41.3 107.6 1.9e-06 28.1 9.9 10.1 9 0 0 9 9 9 4 Coagulation Factor Xa inhibitory site G2F PF07474.12 KER33226.1 - 1.8e-09 37.7 0.0 3.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 G2F domain Ig_C17orf99 PF17736.1 KER33226.1 - 2.2e-08 34.0 0.1 21 5.2 0.0 12.1 14 0 0 14 14 11 0 C17orf99 Ig domain EGF PF00008.27 KER33226.1 - 1.4e-05 25.3 85.6 0.015 15.6 6.7 9.5 8 0 0 8 8 8 5 EGF-like domain V-set_CD47 PF08204.11 KER33226.1 - 4.2e-05 23.5 4.2 10 6.1 0.0 10.7 14 0 0 14 14 12 0 CD47 immunoglobulin-like domain PD40 PF07676.12 KER33226.1 - 0.0093 15.9 0.4 9.5 6.3 0.0 4.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat hEGF PF12661.7 KER33226.1 - 3.9 8.2 67.9 0.18 12.5 5.4 9.5 8 0 0 8 8 8 0 Human growth factor-like EGF T3SS_needle_E PF08988.10 KER33233.1 - 0.0015 18.7 0.1 0.0022 18.1 0.1 1.2 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle 7TM_GPCR_Srw PF10324.9 KER33234.1 - 3.3e-09 36.5 10.1 1.7e-08 34.1 8.1 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 KER33234.1 - 4.8e-07 29.4 7.0 7.4e-07 28.8 7.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4446 PF14584.6 KER33234.1 - 0.15 12.1 1.5 0.6 10.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) GIY-YIG PF01541.24 KER33235.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain Voldacs PF03517.13 KER33237.1 - 5.6e-22 78.4 0.1 7.5e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling zf-AN1 PF01428.16 KER33238.1 - 0.0019 18.3 5.4 0.0019 18.3 5.4 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger IBR PF01485.21 KER33238.1 - 1.1 9.6 9.9 0.045 14.0 1.6 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TMEM213 PF15192.6 KER33240.1 - 0.0047 16.9 0.1 0.0061 16.5 0.1 1.1 1 0 0 1 1 1 1 TMEM213 family KH_1 PF00013.29 KER33242.1 - 4.8e-18 64.7 5.6 2.3e-09 37.0 0.6 2.8 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 KER33242.1 - 0.014 15.4 1.0 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 NusA-like KH domain KH_2 PF07650.17 KER33242.1 - 0.023 14.5 2.5 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 KH domain Retrotran_gag_3 PF14244.6 KER33242.1 - 0.11 12.3 0.0 25 4.8 0.0 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type KH_4 PF13083.6 KER33242.1 - 0.91 9.4 3.9 2.1 8.3 0.5 2.5 2 0 0 2 2 2 0 KH domain HAD_2 PF13419.6 KER33246.1 - 0.048 13.8 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MAM1 PF10434.9 KER33246.1 - 0.086 12.4 3.2 8.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Monopolin complex protein MAM1 MCM PF00493.23 KER33246.1 - 0.098 11.7 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain L_biotic_typeA PF04604.13 KER33246.1 - 0.94 9.4 2.9 30 4.6 0.2 2.4 2 0 0 2 2 2 0 Type-A lantibiotic WH1 PF00568.23 KER33250.1 - 6e-29 100.2 0.0 1.1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 WH1 domain RVT_1 PF00078.27 KER33250.1 - 3.7e-22 78.9 0.0 5.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VASP_tetra PF08776.11 KER33250.1 - 0.00025 20.6 0.3 0.0004 19.9 0.3 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.18 KER33250.1 - 0.0063 16.8 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain NPBW PF15180.6 KER33250.1 - 0.07 13.0 1.9 0.18 11.7 0.1 2.5 3 0 0 3 3 3 0 Neuropeptides B and W TFIIA PF03153.13 KER33250.1 - 0.4 10.6 22.3 0.031 14.3 10.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAN_1 PF00024.26 KER33251.1 - 0.01 15.8 1.3 0.013 15.5 0.3 1.7 2 0 0 2 2 2 0 PAN domain Lamp PF01299.17 KER33252.1 - 2.4e-06 27.5 2.4 0.00068 19.5 1.1 2.3 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) ATP-synt_S1 PF05827.12 KER33252.1 - 0.00049 20.0 0.5 0.0011 18.9 0.1 1.8 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SKG6 PF08693.10 KER33252.1 - 0.0012 18.2 0.3 0.0023 17.3 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Frag1 PF10277.9 KER33252.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family stn_TNFRSF12A PF12191.8 KER33252.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Chordopox_A13L PF05961.11 KER33252.1 - 0.5 10.6 3.1 1.3 9.3 1.1 2.5 2 1 1 3 3 3 0 Chordopoxvirus A13L protein Sec1 PF00995.23 KER33256.1 - 1.9e-96 324.6 0.0 2.5e-96 324.2 0.0 1.2 1 0 0 1 1 1 1 Sec1 family ATP-synt_C PF00137.21 KER33257.1 - 1.2e-36 124.8 26.5 4.3e-21 75.0 7.8 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF4149 PF13664.6 KER33257.1 - 0.022 15.1 2.4 0.09 13.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Clc-like PF07062.12 KER33257.1 - 0.45 10.0 2.4 0.2 11.1 0.4 1.5 2 0 0 2 2 2 0 Clc-like TCR_zetazeta PF11628.8 KER33257.1 - 2.8 7.7 5.5 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain SNF2_N PF00176.23 KER33259.1 - 2.1e-72 243.8 6.4 5.9e-72 242.3 4.8 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KER33259.1 - 1.2e-39 134.9 0.6 3.8e-39 133.2 0.6 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KER33259.1 - 2e-31 109.0 0.2 5.1e-31 107.7 0.2 1.8 1 0 0 1 1 1 1 HAND Helicase_C PF00271.31 KER33259.1 - 4.2e-18 65.7 0.1 2e-17 63.5 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER33259.1 - 2.5e-09 37.4 0.0 7.6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KER33259.1 - 3.3e-07 30.3 0.1 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KER33259.1 - 4.7e-06 26.7 0.6 0.0074 16.5 0.0 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 KER33259.1 - 0.0002 21.1 0.1 0.00057 19.6 0.1 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KER33259.1 - 0.00036 19.8 0.1 0.0012 18.1 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 KER33259.1 - 0.054 13.5 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4800 PF16057.5 KER33259.1 - 0.12 11.7 2.5 0.091 12.0 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) Homeodomain PF00046.29 KER33260.1 - 6.1e-20 70.8 2.7 7.7e-20 70.5 1.3 1.9 2 0 0 2 2 2 1 Homeodomain GIY-YIG PF01541.24 KER33261.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zinc_ribbon_6 PF14599.6 KER33261.1 - 0.045 13.8 0.8 0.11 12.6 0.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon Scramblase PF03803.15 KER33264.1 - 1.3e-32 112.9 0.2 1.9e-32 112.4 0.2 1.1 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.15 KER33266.1 - 5.7e-77 257.9 1.4 6.5e-77 257.8 1.4 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 KER33266.1 - 0.09 12.4 0.0 10 5.7 0.0 2.5 1 1 1 2 2 2 0 LURP-one-related DUF3788 PF12663.7 KER33266.1 - 0.097 12.6 0.1 0.38 10.7 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3788) DUF1751 PF08551.10 KER33268.1 - 0.00061 20.3 2.7 0.00061 20.3 2.7 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Kinesin PF00225.23 KER33270.1 - 1.1e-116 389.5 0.0 2.2e-116 388.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER33270.1 - 1.5e-25 89.9 0.0 4.4e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding UPF0242 PF06785.11 KER33270.1 - 0.00031 20.9 9.7 0.00031 20.9 9.7 2.8 2 2 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus AAA_16 PF13191.6 KER33270.1 - 0.0064 16.9 0.5 0.079 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Kinesin_assoc PF16183.5 KER33270.1 - 0.012 15.8 7.4 0.2 11.8 7.5 2.6 1 1 0 1 1 1 0 Kinesin-associated NACHT PF05729.12 KER33270.1 - 0.052 13.5 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Psb28 PF03912.14 KER33270.1 - 0.079 13.2 0.1 0.52 10.6 0.0 2.5 2 0 0 2 2 2 0 Psb28 protein AAA_22 PF13401.6 KER33270.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.2 4 0 0 4 4 4 0 AAA domain DUF4407 PF14362.6 KER33270.1 - 3.4 6.9 12.4 0.24 10.7 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Rad50_zn_hook PF04423.14 KER33270.1 - 9.5 6.1 9.6 18 5.3 0.2 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif 7tm_1 PF00001.21 KER33271.1 - 6.9e-39 133.7 9.5 8.7e-39 133.4 9.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KER33271.1 - 2.1e-05 24.4 4.0 3.4e-05 23.7 4.0 1.3 1 0 0 1 1 1 1 Olfactory receptor FtsX PF02687.21 KER33271.1 - 0.025 15.0 0.9 0.025 15.0 0.9 3.0 3 1 0 3 3 3 0 FtsX-like permease family MIF4G PF02854.19 KER33272.1 - 4.8e-39 134.2 0.0 4.2e-38 131.1 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 KER33272.1 - 2.9e-18 65.8 1.0 6.5e-18 64.7 1.0 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon CNOT1_CAF1_bind PF16415.5 KER33272.1 - 0.0046 16.4 0.2 0.0099 15.3 0.2 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain rve PF00665.26 KER33273.1 - 0.01 16.0 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Mut7-C PF01927.16 KER33273.1 - 0.088 12.9 0.7 0.12 12.5 0.7 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF3671 PF12420.8 KER33275.1 - 0.58 10.3 4.7 4.7 7.3 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function WD40 PF00400.32 KER33276.1 - 9.1e-30 102.3 21.7 1.2e-05 25.9 0.1 11.7 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33276.1 - 4.7e-18 65.3 0.0 0.022 15.1 0.1 8.1 5 2 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KER33276.1 - 4.7e-09 36.5 0.1 1.2e-08 35.3 0.1 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 KER33276.1 - 5.2e-05 22.7 0.0 0.72 9.1 0.1 3.4 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 KER33276.1 - 0.0024 16.9 0.1 1.2 8.1 0.0 4.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 KER33276.1 - 0.003 17.3 0.2 0.1 12.3 0.1 2.9 3 0 0 3 3 3 1 TUP1-like enhancer of split eIF2A PF08662.11 KER33276.1 - 0.016 15.1 0.1 0.27 11.1 0.0 3.0 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Lgl_C PF08596.10 KER33276.1 - 0.11 11.2 0.0 0.34 9.6 0.0 1.8 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal PD40 PF07676.12 KER33276.1 - 0.11 12.4 0.0 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RVT_1 PF00078.27 KER33278.1 - 1.8e-44 151.9 0.0 3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 KER33278.1 - 0.11 12.8 0.2 67 3.9 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 KER33279.1 - 4.4e-12 45.8 2.9 1.3e-11 44.2 2.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Bunya_G1 PF03557.15 KER33280.1 - 0.0026 15.8 0.1 1.2 7.0 0.0 2.0 2 0 0 2 2 2 2 Bunyavirus glycoprotein G1 Tom5 PF10642.9 KER33280.1 - 0.026 14.5 1.9 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Kinesin PF00225.23 KER33281.1 - 2.1e-103 345.8 0.0 4.3e-103 344.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KER33281.1 - 1.5e-23 83.4 0.0 3.4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 KER33281.1 - 4.2e-15 55.9 0.5 0.0018 19.1 0.0 7.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33281.1 - 0.0049 17.1 0.1 0.4 11.0 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4250 PF14056.6 KER33281.1 - 0.22 11.5 1.9 7.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) NPV_P10 PF05531.12 KER33281.1 - 9.3 6.8 18.7 20 5.7 0.7 4.9 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein JmjC PF02373.22 KER33282.1 - 3e-29 101.7 0.4 4.4e-13 49.6 0.0 3.1 3 0 0 3 3 3 2 JmjC domain, hydroxylase Cupin_8 PF13621.6 KER33282.1 - 4.1e-17 62.7 4.0 6.6e-06 26.0 0.1 3.4 2 1 1 3 3 3 3 Cupin-like domain Cupin_2 PF07883.11 KER33282.1 - 0.0064 16.2 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AAA_23 PF13476.6 KER33283.1 - 7.7e-32 111.4 0.0 7.7e-32 111.4 0.0 8.6 2 1 2 4 4 2 1 AAA domain AAA_21 PF13304.6 KER33283.1 - 3.3e-11 43.5 0.5 0.0018 18.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KER33283.1 - 1.3e-09 37.8 24.5 1.7e-05 24.4 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KER33283.1 - 2.6e-08 34.0 20.6 1.4e-06 28.3 0.1 4.6 1 1 0 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 KER33283.1 - 1.2e-05 25.5 0.0 5.8e-05 23.2 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.14 KER33283.1 - 0.0005 19.9 0.3 0.0005 19.9 0.3 6.1 6 0 0 6 6 6 1 Rad50 zinc hook motif AAA_29 PF13555.6 KER33283.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KER33283.1 - 0.029 13.0 0.0 0.029 13.0 0.0 7.7 4 1 2 7 7 6 0 AAA domain Roc PF08477.13 KER33283.1 - 0.033 14.4 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KER33283.1 - 0.075 13.5 0.0 0.075 13.5 0.0 8.6 4 2 1 5 5 4 0 ABC transporter AAA PF00004.29 KER33283.1 - 0.13 12.7 3.5 2.2 8.7 0.1 4.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PUFD PF16553.5 KER33283.1 - 2.2 8.4 6.6 0.48 10.6 0.4 3.3 3 0 0 3 3 2 0 BCORL-PCGF1-binding domain CEBP_ZZ PF16366.5 KER33284.1 - 8.2e-15 54.8 37.9 0.34 11.2 0.5 7.5 7 0 0 7 7 7 7 Cytoplasmic polyadenylation element-binding protein ZZ domain Glycos_transf_2 PF00535.26 KER33284.1 - 3.6e-14 52.9 7.7 4.5 7.0 0.0 7.3 7 0 0 7 7 7 7 Glycosyl transferase family 2 YL1_C PF08265.11 KER33284.1 - 4.6e-08 32.7 4.3 56 3.6 0.0 7.9 8 0 0 8 8 8 0 YL1 nuclear protein C-terminal domain DUF4920 PF16267.5 KER33284.1 - 1.3e-06 28.3 0.5 1.6e+02 2.4 0.0 7.3 7 0 0 7 7 7 0 Domain of unknown function (DUF4920) DUF3388 PF11868.8 KER33284.1 - 0.00036 19.9 5.2 1.2e+02 1.9 0.0 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF3388) Mesd PF10185.9 KER33284.1 - 0.0016 18.4 14.8 1.3e+02 2.4 0.0 7.7 8 0 0 8 8 8 0 Chaperone for wingless signalling and trafficking of LDL receptor Indigoidine_A PF04227.12 KER33284.1 - 0.04 13.3 13.4 36 3.6 0.0 7.3 8 0 0 8 8 8 0 Indigoidine synthase A like protein Minor_capsid_2 PF11114.8 KER33284.1 - 2.8 8.0 10.0 2.2e+02 1.9 0.1 6.6 8 0 0 8 8 8 0 Minor capsid protein Sugar_tr PF00083.24 KER33286.1 - 1.9e-40 139.1 20.1 1.9e-40 139.1 20.1 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KER33286.1 - 1.1e-16 60.7 46.9 2.3e-10 40.0 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbbQ_C PF08406.10 KER33287.1 - 0.17 12.2 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal Cytochrom_CIII PF02085.16 KER33289.1 - 0.037 14.4 0.2 0.057 13.8 0.2 1.3 1 0 0 1 1 1 0 Class III cytochrome C family GIY-YIG PF01541.24 KER33291.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Metallophos PF00149.28 KER33292.1 - 0.00042 20.9 0.1 0.00075 20.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KER33293.1 - 6e-15 56.3 0.4 3.5e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pex24p PF06398.11 KER33293.1 - 3.6 6.5 6.6 2.1e+02 0.6 6.6 3.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin CASP_C PF08172.12 KER33294.1 - 5.2e-59 199.6 4.7 5.2e-59 199.6 4.7 5.6 2 2 4 6 6 6 1 CASP C terminal DUF4407 PF14362.6 KER33294.1 - 0.0049 16.3 8.0 0.0049 16.3 8.0 4.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 KER33294.1 - 0.015 15.2 4.8 19 5.2 0.0 4.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase VGPC1_C PF16799.5 KER33294.1 - 0.11 12.5 11.3 2.1 8.4 1.2 4.1 4 0 0 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Pox_A_type_inc PF04508.12 KER33294.1 - 0.44 10.5 14.4 4.4 7.3 0.5 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat NADH-UOR_E PF16514.5 KER33294.1 - 0.93 9.9 0.0 0.93 9.9 0.0 3.4 5 0 0 5 5 5 0 putative NADH-ubiquinone oxidoreductase chain E Rootletin PF15035.6 KER33294.1 - 3.3 7.7 50.6 0.14 12.1 11.2 4.7 1 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion IL11 PF07400.11 KER33294.1 - 3.6 7.2 11.3 0.24 11.0 0.6 3.2 3 1 0 3 3 3 0 Interleukin 11 Dna2 PF08696.11 KER33294.1 - 3.6 7.3 7.4 0.58 9.9 0.5 2.6 2 0 0 2 2 2 0 DNA replication factor Dna2 DUF711 PF05167.12 KER33295.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Transposase_22 PF02994.14 KER33296.1 - 0.001 19.2 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 2 L1 transposable element RBD-like domain SIP1 PF04938.12 KER33297.1 - 2.4e-27 96.1 1.2 5.4e-26 91.7 1.2 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) 7tm_1 PF00001.21 KER33299.1 - 5.4e-63 212.8 15.1 9.6e-63 212.0 15.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 KER33299.1 - 2.9e-09 37.1 12.0 2.9e-09 37.1 12.0 1.8 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 KER33299.1 - 6.3e-05 22.7 14.4 0.00014 21.6 14.4 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 KER33299.1 - 0.0089 15.4 18.0 0.58 9.5 13.9 2.5 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF5305 PF17231.2 KER33299.1 - 0.63 9.4 1.8 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Ribosomal_S3_C PF00189.20 KER33302.1 - 1.9e-13 50.7 0.0 2.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Fer4_14 PF13394.6 KER33302.1 - 0.082 13.0 0.0 0.095 12.8 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain SAM_1 PF00536.30 KER33304.1 - 1.1e-12 48.2 0.1 3.9e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PHD PF00628.29 KER33304.1 - 1.2e-09 37.9 7.2 1.2e-09 37.9 7.2 3.0 2 1 1 3 3 3 2 PHD-finger DUF3504 PF12012.8 KER33304.1 - 7.5e-08 32.4 0.4 2.5e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3504) SAM_2 PF07647.17 KER33304.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KER33304.1 - 0.0038 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Mtc PF03820.17 KER33306.1 - 3.1e-135 450.2 0.0 3.9e-135 449.9 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier Stathmin PF00836.19 KER33307.1 - 0.00011 22.2 21.8 0.00034 20.6 3.7 2.8 1 1 2 3 3 3 2 Stathmin family DUF5411 PF17424.2 KER33307.1 - 0.00096 19.1 0.2 1.4 8.9 0.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5411) GatB_Yqey PF02637.18 KER33307.1 - 0.011 15.7 3.6 1.6 8.6 0.4 2.3 1 1 0 2 2 2 0 GatB domain SE PF08491.10 KER33307.1 - 0.012 14.7 4.2 0.88 8.6 0.4 2.1 1 1 1 2 2 2 0 Squalene epoxidase CinA_KH PF18146.1 KER33307.1 - 0.013 15.6 3.3 3.1 8.0 0.2 2.5 2 1 0 2 2 2 0 Damage-inducible protein CinA KH domain DFF-C PF09033.10 KER33307.1 - 0.016 15.1 10.3 0.16 11.9 1.0 2.4 1 1 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain eIF-3c_N PF05470.12 KER33307.1 - 0.019 13.3 15.4 0.024 12.9 7.2 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PepSY_like PF11396.8 KER33307.1 - 0.021 15.4 0.7 9.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like LPD18 PF18832.1 KER33307.1 - 0.023 14.8 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 18 Gly_radical PF01228.21 KER33307.1 - 0.12 12.9 1.7 6.8 7.3 0.1 2.1 1 1 1 2 2 2 0 Glycine radical TPR_5 PF12688.7 KER33307.1 - 0.18 12.0 2.4 4.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat CHDCT2 PF08074.11 KER33307.1 - 1.6 8.9 8.7 0.59 10.3 3.7 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain cNMP_binding PF00027.29 KER33309.1 - 6.1e-40 135.2 0.2 6.3e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KER33309.1 - 1.6e-06 27.7 0.1 3.3e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Rpn3_C PF08375.11 KER33311.1 - 2.9e-27 94.9 1.8 6.6e-27 93.7 1.8 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KER33311.1 - 2.5e-23 82.6 0.0 7.6e-23 81.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KER33311.1 - 0.021 14.9 3.7 0.053 13.7 1.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KER33311.1 - 3.1 8.4 6.2 11 6.6 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat cNMP_binding PF00027.29 KER33313.1 - 2.5e-37 126.8 0.1 2.6e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KER33313.1 - 6.7e-07 28.9 0.1 1.7e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Ribosomal_L22e PF01776.17 KER33315.1 - 4.1e-40 136.6 4.3 1.4e-39 134.8 4.9 1.5 2 0 0 2 2 2 1 Ribosomal L22e protein family 7tm_1 PF00001.21 KER33317.1 - 1.6e-19 70.3 7.2 2.5e-19 69.7 7.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER33317.1 - 9.8e-06 25.1 7.1 9.8e-06 25.1 7.1 2.5 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER33317.1 - 5.5e-05 22.9 8.3 8.4e-05 22.3 6.8 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.9 KER33317.1 - 0.00096 18.6 7.2 0.0013 18.2 5.4 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.21 KER33317.1 - 0.23 11.1 15.6 0.017 14.8 10.4 1.7 2 0 0 2 2 2 0 Srg family chemoreceptor zf-C2H2_4 PF13894.6 KER33318.1 - 5.3e-12 45.5 40.6 0.00029 21.4 0.4 7.0 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER33318.1 - 3.1e-11 43.2 33.4 0.00026 21.3 1.2 7.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KER33318.1 - 9.4e-10 38.4 42.5 0.00027 21.2 1.0 7.0 7 0 0 7 7 6 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 KER33318.1 - 2.8e-05 24.3 10.3 0.00021 21.5 0.9 4.5 3 1 3 6 6 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KER33318.1 - 9.7e-05 22.6 5.7 0.2 12.1 0.1 4.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KER33318.1 - 0.0011 19.6 15.4 1 10.0 0.1 4.7 2 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 KER33318.1 - 0.03 14.2 3.6 2.8 7.8 0.0 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 KER33318.1 - 0.038 13.8 3.9 0.59 10.0 0.0 3.7 2 1 1 3 3 3 0 GAGA factor zf-C2H2_11 PF16622.5 KER33318.1 - 0.045 13.5 23.3 0.54 10.1 0.3 4.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KER33318.1 - 0.07 13.4 0.1 0.07 13.4 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 KER33318.1 - 1 9.4 15.8 0.19 11.8 1.7 3.6 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.10 KER33318.1 - 1.5 8.6 8.7 0.031 14.0 1.5 1.9 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 KER33318.1 - 2.2 8.4 21.8 0.15 12.1 1.0 4.8 3 1 2 5 5 5 0 BED zinc finger zf-C2H2_2 PF12756.7 KER33318.1 - 4.6 7.6 19.3 15 6.0 7.7 4.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1644 PF07800.12 KER33320.1 - 0.00046 20.3 1.5 0.4 10.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) zf-C2H2_9 PF16293.5 KER33320.1 - 0.034 14.0 0.4 0.1 12.5 0.4 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KER33320.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KER33320.1 - 0.42 11.0 4.7 2.1 8.7 1.0 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KER33320.1 - 0.57 11.2 19.6 1.3 10.0 0.1 5.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KER33320.1 - 0.57 10.7 0.1 0.57 10.7 0.1 5.1 5 1 0 5 5 5 0 Zinc finger, C2H2 type Rad60-SLD PF11976.8 KER33321.1 - 3e-08 33.4 0.1 3.7e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SRP9-21 PF05486.12 KER33321.1 - 0.021 15.2 0.0 0.023 15.0 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Annexin PF00191.20 KER33322.1 - 1.5e-93 306.9 11.0 1.2e-23 83.0 0.2 4.1 4 0 0 4 4 4 4 Annexin RNA_binding PF01877.17 KER33322.1 - 0.015 15.5 1.9 0.24 11.7 0.2 2.7 1 1 1 2 2 2 0 RNA binding Myb_DNA-bind_7 PF15963.5 KER33322.1 - 0.072 13.0 0.0 7.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Myb DNA-binding like GP24_25 PF17388.2 KER33322.1 - 0.092 12.7 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Annexin PF00191.20 KER33324.1 - 4.8e-126 410.9 14.5 1.6e-25 88.9 0.2 6.1 5 1 1 6 6 6 6 Annexin Sigma70_ner PF04546.13 KER33324.1 - 1.9e-05 24.7 9.6 0.0068 16.3 0.9 3.2 1 1 3 4 4 4 2 Sigma-70, non-essential region DUF1400 PF07176.11 KER33324.1 - 7e-05 23.1 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1400) Myb_DNA-bind_7 PF15963.5 KER33324.1 - 0.00059 19.7 3.8 1.4 8.8 0.0 4.6 5 0 0 5 5 5 1 Myb DNA-binding like GP24_25 PF17388.2 KER33324.1 - 0.00074 19.5 0.0 3.1 7.8 0.0 3.0 3 0 0 3 3 3 2 Tail assembly gene products 24 & 25 RPAP3_C PF13877.6 KER33324.1 - 0.004 17.6 0.0 7.1 7.2 0.0 2.8 3 0 0 3 3 3 2 Potential Monad-binding region of RPAP3 Stn1_C PF12659.7 KER33324.1 - 0.093 12.7 0.1 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH HTH_Tnp_Tc3_2 PF01498.18 KER33324.1 - 0.1 12.8 0.1 87 3.5 0.0 4.0 4 0 0 4 4 4 0 Transposase T2SSF PF00482.23 KER33324.1 - 0.13 12.2 0.2 0.42 10.6 0.2 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Annexin PF00191.20 KER33325.1 - 8.9e-80 262.7 10.7 1.6e-22 79.4 0.0 4.4 4 0 0 4 4 4 4 Annexin FAM221 PF14753.6 KER33326.1 - 3.1e-27 95.4 14.2 1.4e-25 90.1 14.2 2.1 1 1 0 1 1 1 1 Protein FAM221A/B Synapsin_C PF02750.14 KER33328.1 - 3.1e-74 248.9 0.0 4.4e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 KER33328.1 - 9.2e-40 135.0 0.0 2e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain Pou PF00157.17 KER33333.1 - 7.3e-30 102.8 0.0 1.7e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 KER33333.1 - 4.4e-18 64.9 4.4 1e-17 63.7 4.4 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 KER33333.1 - 0.00061 20.1 0.0 0.0083 16.4 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DUF2856 PF11043.8 KER33333.1 - 0.0043 17.1 0.4 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2856) Homeobox_KN PF05920.11 KER33333.1 - 0.012 15.5 1.4 0.035 14.0 0.1 2.6 2 0 0 2 2 2 0 Homeobox KN domain CH PF00307.31 KER33335.1 - 1.4e-28 99.2 0.0 2.6e-14 53.3 0.2 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KER33335.1 - 2.4e-07 30.5 0.0 0.00037 20.3 0.0 3.1 2 2 1 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 KER33335.1 - 2.4e-06 27.6 0.0 6.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 CH-like domain in sperm protein Mlh1_C PF16413.5 KER33336.1 - 1.7e-73 247.3 0.0 3.1e-73 246.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KER33336.1 - 5.4e-20 71.2 0.0 3.8e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KER33336.1 - 3.2e-11 43.2 0.0 7.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KER33336.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BACK PF07707.15 KER33337.1 - 2.6e-15 56.4 6.6 3.3e-13 49.6 3.0 2.4 2 0 0 2 2 2 2 BTB And C-terminal Kelch Kelch_1 PF01344.25 KER33337.1 - 6.5e-15 54.4 1.7 0.0045 16.5 0.1 6.5 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 KER33337.1 - 2.2e-10 40.6 1.9 0.18 12.2 0.0 5.4 4 1 1 5 5 5 3 Galactose oxidase, central domain BTB PF00651.31 KER33337.1 - 1.2e-09 38.4 2.2 1.2e-09 38.3 0.3 2.1 3 0 0 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.6 KER33337.1 - 2.5e-09 37.0 2.3 0.0078 16.2 0.0 5.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KER33337.1 - 2.6e-09 37.0 6.7 0.0013 18.9 0.6 5.9 4 2 2 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KER33337.1 - 6.8e-08 32.3 2.5 0.45 10.6 0.2 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KER33337.1 - 1.8e-06 27.7 0.7 2.3 8.3 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Sec1 PF00995.23 KER33338.1 - 4.2e-99 333.4 0.0 5.6e-98 329.6 0.0 2.0 1 1 0 1 1 1 1 Sec1 family Ras PF00071.22 KER33339.1 - 1.3e-35 122.4 0.0 1.5e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER33339.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER33339.1 - 0.0099 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER33339.1 - 0.058 12.9 0.0 0.33 10.5 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MatE PF01554.18 KER33341.1 - 6.2e-44 149.5 26.8 1.4e-28 99.6 7.2 3.7 4 0 0 4 4 4 3 MatE PPDK_N PF01326.19 KER33341.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Polysacc_synt_C PF14667.6 KER33341.1 - 3.7 7.6 38.6 0.5 10.4 6.1 4.3 4 1 1 5 5 5 0 Polysaccharide biosynthesis C-terminal domain PDEase_I PF00233.19 KER33343.1 - 4.1e-73 246.0 1.0 6.3e-73 245.4 1.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 KER33343.1 - 3.9e-21 76.1 0.0 2.6e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 KER33343.1 - 3.5e-11 43.6 0.0 4.3e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 GAF domain Yos9_DD PF17880.1 KER33343.1 - 0.044 13.9 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Yos9 dimerzation domain bZIP_2 PF07716.15 KER33344.1 - 8.2e-12 45.0 11.8 1.8e-11 43.9 11.8 1.6 1 1 0 1 1 1 1 Basic region leucine zipper Speriolin_N PF15058.6 KER33344.1 - 0.00052 20.2 0.4 0.00052 20.2 0.4 1.6 2 0 0 2 2 2 1 Speriolin N terminus bZIP_1 PF00170.21 KER33344.1 - 0.0023 18.0 13.3 0.0034 17.4 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor KASH_CCD PF14662.6 KER33344.1 - 0.0073 16.2 2.4 0.0096 15.8 2.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_Maf PF03131.17 KER33344.1 - 0.048 14.2 7.1 0.076 13.5 7.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Peptidase_M28 PF04389.17 KER33345.1 - 1.5e-17 63.9 0.0 4.6e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Acyl-CoA_dh_1 PF00441.24 KER33347.1 - 1.1e-50 171.8 2.7 1.1e-50 171.8 2.7 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KER33347.1 - 1.3e-30 106.3 0.1 3.2e-30 105.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KER33347.1 - 1.9e-25 88.9 0.1 3.2e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KER33347.1 - 8.4e-23 81.1 1.9 1.3e-22 80.5 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Coronavirus_5 PF05528.11 KER33347.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Coronavirus gene 5 protein PCI PF01399.27 KER33348.1 - 3.6e-15 56.4 0.2 7e-15 55.4 0.2 1.5 1 0 0 1 1 1 1 PCI domain HOOK PF05622.12 KER33349.1 - 1.2e-10 40.2 0.1 1.2e-10 40.2 0.1 6.4 3 1 2 5 5 5 2 HOOK protein ZapB PF06005.12 KER33349.1 - 0.02 15.3 1.1 0.02 15.3 1.1 15.3 9 3 3 13 13 13 0 Cell division protein ZapB TBD PF12845.7 KER33349.1 - 4.4 7.3 13.7 0.22 11.5 3.5 3.8 3 0 0 3 3 3 0 TBD domain HEAT_2 PF13646.6 KER33350.1 - 2.1e-08 34.4 11.4 0.072 13.5 0.0 7.7 6 1 0 7 7 7 3 HEAT repeats HEAT PF02985.22 KER33350.1 - 2.1e-05 24.4 30.1 0.82 10.1 0.6 10.0 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KER33350.1 - 0.0015 19.0 2.2 0.023 15.3 0.2 3.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KER33350.1 - 0.012 14.2 2.5 2.5 6.6 0.1 3.8 3 1 0 3 3 3 0 Adaptin N terminal region RTP1_C1 PF10363.9 KER33350.1 - 0.45 10.7 2.1 55 4.0 0.1 5.0 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CG-1 PF03859.16 KER33351.1 - 6.3e-33 113.0 0.1 1.5e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 CG-1 domain IQ PF00612.27 KER33351.1 - 0.00099 18.7 10.5 0.0063 16.2 1.2 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif YacG PF03884.14 KER33351.1 - 0.028 14.1 1.4 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG E1_dh PF00676.20 KER33352.1 - 1.7e-66 224.2 0.0 2.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KER33352.1 - 2.1e-05 23.9 0.0 0.0001 21.7 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KER33352.1 - 0.0041 16.9 0.0 0.036 13.8 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RhoGAP PF00620.27 KER33354.1 - 3.9e-40 137.1 0.0 1.1e-39 135.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KER33354.1 - 2.6e-12 46.9 0.2 7.8e-12 45.3 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KER33354.1 - 4.3e-11 42.3 0.0 9.8e-11 41.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER33354.1 - 6.1e-09 35.6 0.1 1.4e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER33354.1 - 2.4e-07 30.3 0.0 5.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.11 KER33354.1 - 0.31 11.5 0.8 1.1 9.7 0.8 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 KER33354.1 - 8.4 6.6 8.3 0.25 11.4 0.2 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation FHA PF00498.26 KER33355.1 - 1.1e-18 67.4 0.2 2.4e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KER33355.1 - 1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 KER33357.1 - 5.5e-63 212.8 0.0 7.7e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33357.1 - 1.2e-36 126.4 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KER33357.1 - 2.2e-05 23.9 0.3 5.4e-05 22.7 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KER33357.1 - 0.00042 19.7 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER33357.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KER33357.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KER33357.1 - 0.029 14.0 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 RIO1 family 7tm_1 PF00001.21 KER33358.1 - 4.4e-51 173.7 23.7 4.4e-51 173.7 23.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER33358.1 - 2.7e-14 53.2 21.6 4e-14 52.6 21.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 KER33358.1 - 3.7e-11 43.1 19.0 3.7e-11 43.1 19.0 2.0 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx FCH PF00611.23 KER33359.1 - 1.5e-11 44.4 2.6 3.3e-11 43.3 0.1 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain muHD PF10291.9 KER33359.1 - 3.4e-11 43.1 0.0 0.00035 20.1 0.0 3.1 2 1 0 2 2 2 2 Muniscin C-terminal mu homology domain RVT_1 PF00078.27 KER33359.1 - 5.4e-11 42.4 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5426 PF17473.2 KER33359.1 - 0.01 16.1 0.6 0.021 15.1 0.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5426) AKAP7_RIRII_bdg PF10470.9 KER33359.1 - 0.084 12.9 0.3 0.21 11.7 0.3 1.6 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF1043 PF06295.12 KER33359.1 - 0.79 9.7 8.7 5.9 6.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Fez1 PF06818.15 KER33361.1 - 0.0034 17.8 14.2 0.0034 17.8 14.2 3.3 1 1 1 3 3 3 2 Fez1 DivIC PF04977.15 KER33361.1 - 0.023 14.5 0.3 0.023 14.5 0.3 6.8 3 1 5 8 8 8 0 Septum formation initiator Surfac_D-trimer PF09006.11 KER33361.1 - 0.24 11.3 2.3 14 5.6 0.0 3.5 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Atg14 PF10186.9 KER33361.1 - 2.6 7.1 50.6 2.6 7.1 17.2 3.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2408 PF10303.9 KER33362.1 - 0.0054 17.3 1.3 0.82 10.2 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2408) E1_DerP2_DerF2 PF02221.15 KER33363.1 - 3.5e-25 89.0 0.6 4.1e-25 88.8 0.6 1.1 1 0 0 1 1 1 1 ML domain Cadherin-like PF12733.7 KER33363.1 - 0.12 13.0 0.0 21 5.7 0.0 2.1 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain 7tm_1 PF00001.21 KER33364.1 - 2.7e-13 49.9 8.7 3.4e-13 49.5 8.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER33364.1 - 0.00013 21.4 7.4 0.00023 20.7 7.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CTP_transf_1 PF01148.20 KER33364.1 - 0.043 13.6 1.9 0.086 12.6 1.9 1.5 1 1 0 1 1 1 0 Cytidylyltransferase family 7TM_GPCR_Srab PF10292.9 KER33364.1 - 0.051 12.5 5.5 0.03 13.3 1.3 2.1 1 1 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor MFS_1 PF07690.16 KER33365.1 - 3.4e-15 55.8 55.1 1e-12 47.7 30.6 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DNA_photolyase PF00875.18 KER33368.1 - 2e-08 34.4 0.0 1.2e-07 31.9 0.0 2.3 2 1 0 2 2 2 1 DNA photolyase UCH PF00443.29 KER33371.1 - 2.2e-19 70.0 0.0 1.9e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KER33371.1 - 1.2e-09 38.2 0.1 2.5e-08 33.9 0.0 2.4 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KER33371.1 - 1.9e-06 27.5 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KER33371.1 - 0.00013 22.5 0.0 2.2 9.0 0.0 3.7 3 0 0 3 3 3 2 DUSP domain Acetyltransf_1 PF00583.25 KER33372.1 - 2.2e-13 50.5 0.0 3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KER33372.1 - 9.7e-09 35.2 0.0 6.1e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KER33372.1 - 4.3e-08 33.5 0.3 1e-07 32.3 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KER33372.1 - 4.4e-06 26.9 0.0 7.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KER33372.1 - 0.0001 22.0 0.0 0.00014 21.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER33372.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KER33372.1 - 0.037 14.7 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PBC PF03792.13 KER33373.1 - 4.5e-81 271.2 0.0 7.1e-81 270.5 0.0 1.3 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 KER33373.1 - 7.2e-20 70.6 0.5 1.6e-19 69.5 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER33373.1 - 6.9e-16 57.9 0.0 2.3e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KER33373.1 - 0.0019 18.0 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KER33373.1 - 0.0099 15.9 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix K_channel_TID PF07941.11 KER33373.1 - 0.02 15.4 2.6 0.02 15.4 2.6 2.9 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain NUDIX PF00293.28 KER33375.1 - 0.0014 18.7 0.0 0.18 11.8 0.1 2.6 2 1 0 2 2 2 2 NUDIX domain LRR_4 PF12799.7 KER33377.1 - 0.051 14.0 0.5 3.2 8.3 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LIM PF00412.22 KER33379.1 - 1.2e-26 92.7 16.4 8.3e-13 48.4 10.4 2.2 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 KER33379.1 - 1 9.5 15.4 1.7e+03 -0.9 14.9 3.5 1 1 0 1 1 1 0 Double zinc ribbon TPR_12 PF13424.6 KER33381.1 - 4.5e-07 30.1 5.3 2.3e-06 27.8 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER33381.1 - 1.7e-05 24.6 0.4 0.19 12.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KER33381.1 - 1.8e-05 24.4 1.5 0.23 11.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KER33381.1 - 0.00016 21.5 2.7 0.27 11.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER33381.1 - 0.0016 18.2 0.5 1.5 8.8 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3450 PF11932.8 KER33381.1 - 0.03 13.6 1.3 0.073 12.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TPR_7 PF13176.6 KER33381.1 - 0.083 13.0 1.7 8.4 6.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1878 PF08963.10 KER33381.1 - 0.18 12.3 3.7 0.56 10.7 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) DUF2572 PF10833.8 KER33382.1 - 0.064 13.0 2.8 0.1 12.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Cadherin PF00028.17 KER33383.1 - 2.3e-37 127.3 12.2 8e-10 39.0 0.2 8.9 8 2 1 9 9 9 7 Cadherin domain Cadherin_2 PF08266.12 KER33383.1 - 5.4e-11 42.2 0.0 2.3e-07 30.6 0.0 3.7 3 0 0 3 3 3 2 Cadherin-like Cadherin_3 PF16184.5 KER33383.1 - 5e-05 23.3 14.2 0.5 10.4 0.1 5.2 5 0 0 5 5 5 3 Cadherin-like Cadherin PF00028.17 KER33385.1 - 2.9e-23 82.1 0.0 1.3e-10 41.5 0.0 2.9 3 0 0 3 3 3 2 Cadherin domain Cadherin_2 PF08266.12 KER33385.1 - 0.048 13.5 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 Cadherin-like DUF384 PF04064.13 KER33388.1 - 1.1e-19 70.0 2.0 2.8e-19 68.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 KER33388.1 - 4.6e-18 65.6 0.1 6.7e-16 58.5 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF383) NP1-WLL PF11733.8 KER33388.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Nnf1 PF03980.14 KER33392.1 - 8.2e-06 26.2 0.6 2.1e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 Nnf1 FAA_hydrolase_N PF09298.11 KER33392.1 - 0.04 14.1 0.6 0.079 13.2 0.2 1.7 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal APCDDC PF14921.6 KER33392.1 - 0.041 13.3 1.5 0.045 13.2 1.5 1.4 1 1 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 RVT_1 PF00078.27 KER33393.1 - 2.6e-16 59.8 0.0 5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Clathrin PF00637.20 KER33393.1 - 1.9e-11 44.0 0.4 1.4e-07 31.5 0.0 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS Mcl1_mid PF12341.8 KER33393.1 - 0.00091 18.7 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region Vps39_1 PF10366.9 KER33393.1 - 0.0011 19.2 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 KER33393.1 - 0.015 16.2 0.2 0.015 16.2 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40_like PF17005.5 KER33393.1 - 0.034 13.5 0.2 0.062 12.6 0.2 1.3 1 0 0 1 1 1 0 WD40-like domain HlyD_D4 PF16572.5 KER33393.1 - 0.11 12.4 0.2 24 4.9 0.1 2.5 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB Ctr PF04145.15 KER33394.1 - 5.8e-30 104.9 0.0 8.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.6 KER33394.1 - 0.073 13.2 3.7 0.17 12.0 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Isy1 PF06246.12 KER33395.1 - 3e-45 154.8 2.8 4.5e-45 154.2 2.8 1.2 1 0 0 1 1 1 1 Isy1-like splicing family CLTH PF10607.9 KER33397.1 - 5.3e-16 58.8 0.4 1.1e-15 57.8 0.1 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain PSCyt3 PF07627.11 KER33397.1 - 0.031 14.6 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Siva PF05458.12 KER33398.1 - 0.06 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Mtp PF03821.16 KER33399.1 - 0.093 12.3 21.7 0.28 10.8 4.0 3.5 3 1 1 4 4 4 0 Golgi 4-transmembrane spanning transporter Amastin PF07344.11 KER33399.1 - 1.3 8.9 12.0 2.9 7.7 5.8 2.2 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF4728 PF15860.5 KER33399.1 - 8.8 7.1 14.4 1.2 9.9 8.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) Chor_lyase PF04345.13 KER33400.1 - 0.044 13.4 1.8 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Chorismate lyase PHD PF00628.29 KER33402.1 - 1.6e-25 88.8 72.5 1.3e-09 37.7 9.1 7.1 6 1 1 7 7 7 5 PHD-finger zf-HC5HC2H PF13771.6 KER33402.1 - 3.5e-08 33.6 1.6 3.5e-08 33.6 1.6 6.5 4 3 2 7 7 7 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KER33402.1 - 0.00013 22.1 3.0 0.00013 22.1 3.0 5.4 3 2 2 5 5 5 2 PHD-zinc-finger like domain PHD_2 PF13831.6 KER33402.1 - 0.002 17.7 1.8 0.002 17.7 1.8 6.2 6 0 0 6 6 6 4 PHD-finger DUF2052 PF09747.9 KER33402.1 - 0.24 11.5 6.0 18 5.4 0.0 2.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) zf-C2H2_6 PF13912.6 KER33402.1 - 0.74 9.9 3.2 5.2 7.2 0.2 3.8 2 0 0 2 2 2 0 C2H2-type zinc finger rRNA_processing PF08524.11 KER33402.1 - 1.2 9.2 13.0 4.3 7.4 13.0 1.9 1 0 0 1 1 1 0 rRNA processing tRNA_lig_CPD PF08302.11 KER33402.1 - 1.6 8.1 9.1 4.6 6.6 9.1 1.7 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain NADH-G_4Fe-4S_3 PF10588.9 KER33402.1 - 2.1 7.9 7.5 0.65 9.6 0.1 3.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 7tm_1 PF00001.21 KER33403.1 - 2.1e-09 37.1 8.6 7e-09 35.4 8.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER33403.1 - 5.6e-08 32.4 11.4 8.1e-08 31.9 11.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 KER33403.1 - 0.001 18.8 18.9 0.0028 17.3 18.9 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.6 KER33405.1 - 9.7e-53 175.8 147.3 3.7e-09 36.2 8.2 11.8 3 3 13 17 17 17 16 Leucine rich repeat LRR_4 PF12799.7 KER33405.1 - 4.3e-36 122.3 78.6 4.5e-05 23.7 0.5 13.3 6 4 9 16 16 16 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KER33405.1 - 2.1e-07 30.5 77.4 1.5 9.6 0.0 19.5 20 2 1 21 21 21 4 Leucine Rich Repeat LRR_9 PF14580.6 KER33405.1 - 4.5e-06 26.3 32.0 0.0035 16.9 0.1 6.1 2 1 5 7 7 7 3 Leucine-rich repeat LRR_5 PF13306.6 KER33405.1 - 0.0023 17.9 0.7 5.1 7.1 0.1 4.3 3 1 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KER33405.1 - 0.011 15.8 59.5 0.27 11.4 0.2 14.6 16 0 0 16 16 16 0 Leucine Rich repeat RsmF_methylt_CI PF17126.5 KER33405.1 - 0.013 15.6 4.8 20 5.3 0.0 6.1 5 2 2 7 7 7 0 RsmF rRNA methyltransferase first C-terminal domain Arb1 PF09692.10 KER33405.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 NKWYS PF10364.9 KER33405.1 - 0.28 11.3 0.8 1.7 8.8 0.1 2.6 3 0 0 3 3 3 0 Putative capsular polysaccharide synthesis protein EndIII_4Fe-2S PF10576.9 KER33406.1 - 0.23 11.9 1.0 0.4 11.1 0.3 1.9 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III WD40 PF00400.32 KER33408.1 - 1.3e-07 32.1 9.7 0.065 14.1 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33408.1 - 5.6e-06 26.6 0.0 0.59 10.5 0.0 5.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KER33408.1 - 0.001 18.7 0.2 0.003 17.2 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.6 KER33408.1 - 0.015 14.6 0.7 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rhodanese PF00581.20 KER33409.1 - 3.5e-12 46.8 0.0 5.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Calx-beta PF03160.14 KER33411.1 - 1.3e-53 179.3 12.8 1.3e-29 102.3 1.0 3.2 4 0 0 4 4 4 2 Calx-beta domain Na_Ca_ex PF01699.24 KER33411.1 - 1.4e-52 177.6 42.3 8.4e-29 100.5 13.6 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 KER33411.1 - 4.3e-27 95.1 2.1 7.4e-27 94.3 2.1 1.3 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain ANAPC10 PF03256.16 KER33412.1 - 6e-61 205.3 0.0 1.4e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Bromodomain PF00439.25 KER33412.1 - 1.1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF3543 PF12063.8 KER33412.1 - 0.043 13.2 0.3 0.075 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) DSPc PF00782.20 KER33414.1 - 1.7e-33 115.2 0.0 3.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KER33414.1 - 0.025 14.9 0.1 0.07 13.4 0.1 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KER33414.1 - 0.041 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TGF_beta_GS PF08515.12 KER33414.1 - 0.12 11.9 0.1 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF5082 PF16888.5 KER33418.1 - 1.6 9.0 4.4 19 5.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) VEGFR-2_TMD PF17988.1 KER33419.1 - 0.42 10.1 4.0 0.76 9.3 4.0 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Nudc_N PF14050.6 KER33421.1 - 0.033 14.2 4.9 4.8 7.2 0.1 3.3 3 0 0 3 3 3 0 N-terminal conserved domain of Nudc. Glyco_hydro_49N PF17433.2 KER33421.1 - 0.12 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Galactosyl_T PF01762.21 KER33424.1 - 3.1e-40 138.1 0.0 3.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 KER33424.1 - 0.041 13.3 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 Fringe-like Glyco_tranf_2_3 PF13641.6 KER33424.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 cNMP_binding PF00027.29 KER33425.1 - 2e-18 66.2 2.6 2.2e-09 37.2 0.2 4.3 2 2 1 3 3 3 3 Cyclic nucleotide-binding domain RIIa PF02197.17 KER33425.1 - 0.00088 18.9 0.5 0.0021 17.7 0.5 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Fzo_mitofusin PF04799.13 KER33426.1 - 3.5e-54 182.7 4.4 8.6e-54 181.4 1.0 2.6 2 0 0 2 2 2 1 fzo-like conserved region Dynamin_N PF00350.23 KER33426.1 - 8.8e-24 84.4 0.0 4.7e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KER33426.1 - 7.1e-08 32.5 0.0 4.3e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Baculo_PEP_C PF04513.12 KER33426.1 - 0.057 13.5 4.3 0.23 11.5 2.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIG1 PF04548.16 KER33426.1 - 0.56 9.5 4.5 0.6 9.4 0.1 2.6 2 0 0 2 2 2 0 AIG1 family Acyl-CoA_dh_C PF12806.7 KER33426.1 - 1.1 9.5 3.4 23 5.2 0.3 3.1 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like zf-C4H2 PF10146.9 KER33426.1 - 9.6 6.4 11.5 0.14 12.5 0.6 2.6 3 0 0 3 3 3 0 Zinc finger-containing protein CDP-OH_P_transf PF01066.21 KER33430.1 - 4.1e-09 37.1 0.2 4.1e-09 37.1 0.2 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PRT_C PF08372.10 KER33430.1 - 0.03 14.1 0.2 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal MFS_Mycoplasma PF07672.13 KER33430.1 - 0.069 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter RF-1 PF00472.20 KER33431.1 - 0.035 14.0 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 RF-1 domain B-block_TFIIIC PF04182.12 KER33432.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC GH-E PF14410.6 KER33433.1 - 0.19 12.2 3.0 1.3 9.5 0.8 2.5 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PP1_inhibitor PF05361.12 KER33434.1 - 3.1e-08 33.7 1.7 3.8e-08 33.5 1.7 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor DUF2701 PF10857.8 KER33437.1 - 0.064 13.3 0.1 15 5.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) Lig_chan-Glu_bd PF10613.9 KER33441.1 - 3e-21 75.8 0.0 5.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site GIY-YIG PF01541.24 KER33441.1 - 0.026 14.8 2.2 0.061 13.6 0.2 2.5 2 0 0 2 2 2 0 GIY-YIG catalytic domain Lig_chan PF00060.26 KER33442.1 - 1.6e-49 167.5 0.2 2.4e-49 167.0 0.2 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 KER33442.1 - 9.2e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 KER33442.1 - 2.8e-06 26.9 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF5409 PF17421.2 KER33442.1 - 0.0081 16.9 0.1 0.32 11.7 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5409) Ion_trans_2 PF07885.16 KER33442.1 - 2 8.5 6.2 5 7.1 6.2 1.7 1 1 0 1 1 1 0 Ion channel SBP_bac_3 PF00497.20 KER33443.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SH3_17 PF18350.1 KER33443.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease SH3 domain CEP170_C PF15308.6 KER33444.1 - 0.01 14.5 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 CEP170 C-terminus SCO1-SenC PF02630.14 KER33445.1 - 2.1e-24 85.9 0.0 2.9e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KER33445.1 - 0.00017 21.5 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NfrA_C PF13283.6 KER33445.1 - 0.024 14.1 0.0 3.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Bacteriophage N adsorption protein A C-term RACo_C_ter PF14574.6 KER33445.1 - 0.087 11.9 0.2 9.4 5.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain Thioredoxin_8 PF13905.6 KER33445.1 - 0.088 13.2 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KER33445.1 - 0.19 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin PGM_PMM_I PF02878.16 KER33446.1 - 2.1e-36 124.7 0.0 3.8e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KER33446.1 - 2.9e-19 69.6 0.0 7.3e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KER33446.1 - 1.5e-12 47.7 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KER33446.1 - 0.00029 21.0 0.0 0.00075 19.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CUT PF02376.15 KER33447.1 - 2.1e-31 107.9 0.6 4e-31 107.0 0.6 1.5 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 KER33447.1 - 4.9e-11 42.3 0.6 1.5e-10 40.8 0.6 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER33447.1 - 0.00012 21.8 0.0 0.00045 20.1 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain MRG PF05712.13 KER33448.1 - 2e-44 151.3 0.0 4e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 MRG DUF3221 PF11518.8 KER33448.1 - 0.013 15.9 0.3 0.026 14.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Tudor-knot PF11717.8 KER33448.1 - 0.14 12.1 0.3 1 9.3 0.5 2.3 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Homeobox_KN PF05920.11 KER33450.1 - 1.6e-20 72.7 1.0 3.9e-20 71.5 1.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KER33450.1 - 6.6e-08 32.3 2.0 7.9e-08 32.0 0.4 1.9 2 0 0 2 2 2 1 Homeodomain Tubulin PF00091.25 KER33451.1 - 9.4e-68 228.3 0.0 1.4e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KER33451.1 - 7.9e-46 155.3 0.1 1.4e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KER33451.1 - 0.00081 19.7 0.0 0.0026 18.1 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KER33451.1 - 0.032 13.4 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Sec7 PF01369.20 KER33453.1 - 2.1e-50 171.0 0.0 3.3e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KER33453.1 - 5.3e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Macro PF01661.21 KER33455.1 - 8.9e-34 116.1 0.4 1.2e-33 115.6 0.4 1.2 1 0 0 1 1 1 1 Macro domain Ribosomal_L30_N PF08079.12 KER33457.1 - 3.1e-05 24.1 10.9 7e-05 23.0 10.9 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KER33457.1 - 6.7e-05 22.7 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PAS_8 PF13188.7 KER33457.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 KER33457.1 - 0.04 14.1 0.6 2.1 8.5 0.0 2.7 2 1 1 3 3 3 0 PAS fold DUF1241 PF06840.11 KER33460.1 - 1.1e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Bestrophin PF01062.21 KER33460.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel GCFC PF07842.12 KER33461.1 - 1.3e-24 87.3 14.1 7e-17 61.9 4.1 2.3 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KER33461.1 - 2.8e-19 69.4 5.7 3.4e-19 69.1 4.4 1.8 1 1 1 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KER33461.1 - 9.3e-16 57.5 1.5 2.3e-15 56.2 1.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KER33461.1 - 0.0052 16.8 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 G-patch domain Peptidase_C14 PF00656.22 KER33462.1 - 1.2e-37 130.3 0.0 1.8e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 KER33462.1 - 2.7e-10 40.1 0.1 5.1e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain CARD_2 PF16739.5 KER33462.1 - 0.00061 19.7 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain Transferrin PF00405.17 KER33462.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Transferrin NqrM PF04400.13 KER33466.1 - 0.36 10.6 3.9 3.8 7.4 0.1 3.0 2 1 0 2 2 2 0 (Na+)-NQR maturation NqrM Vault PF01505.18 KER33467.1 - 9.3e-10 38.5 0.0 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Major Vault Protein repeat domain HLH PF00010.26 KER33470.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain SPATA6 PF14909.6 KER33471.1 - 0.12 12.5 0.0 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 Spermatogenesis-assoc protein 6 Linker_histone PF00538.19 KER33472.1 - 2.8e-18 66.0 0.1 3.2e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 linker histone H1 and H5 family Il2rg PF15874.5 KER33474.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain XPG_I_2 PF12813.7 KER33476.1 - 0.4 10.1 2.5 4 6.8 0.1 2.1 1 1 1 2 2 2 0 XPG domain containing HCV_capsid PF01543.17 KER33476.1 - 0.72 10.1 4.1 3.6 7.8 0.3 2.1 1 1 1 2 2 2 0 Hepatitis C virus capsid protein Clr2_transil PF16761.5 KER33476.1 - 1.2 10.0 5.7 8.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 G-gamma PF00631.22 KER33477.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 GGL domain DUF667 PF05018.13 KER33478.1 - 1.2e-72 243.6 0.0 1.3e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MBT PF02820.18 KER33479.1 - 7.6e-40 135.1 0.5 6.5e-16 58.4 0.0 4.7 4 0 0 4 4 4 4 mbt repeat SLED PF12140.8 KER33479.1 - 8.9e-17 61.6 0.0 1.1e-15 58.1 0.0 2.3 1 1 0 1 1 1 1 SLED domain RVT_1 PF00078.27 KER33481.1 - 3.4e-15 56.2 0.0 6.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 KER33481.1 - 3e-09 36.9 27.8 1.2e-06 28.6 1.3 5.1 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER33481.1 - 2.1e-07 31.0 34.5 0.00074 19.8 1.6 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER33481.1 - 2.5e-06 27.8 31.9 0.00037 21.1 1.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER33481.1 - 1.2e-05 25.5 23.4 0.0062 16.8 3.6 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER33481.1 - 0.018 15.4 1.7 0.018 15.4 1.7 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PHD PF00628.29 KER33481.1 - 0.77 9.7 10.4 2.2 8.2 2.6 2.8 2 1 0 2 2 2 0 PHD-finger Ta0938 PF11494.8 KER33481.1 - 0.91 9.8 3.1 1.3 9.3 0.6 2.3 1 1 1 2 2 2 0 Ta0938 zf-C2H2_9 PF16293.5 KER33481.1 - 1.6 8.6 4.7 12 5.9 0.0 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc-ribbons_6 PF07191.12 KER33481.1 - 7.8 6.6 12.2 23 5.1 0.5 3.2 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_6 PF13912.6 KER33481.1 - 9.6 6.3 27.7 0.8 9.8 1.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_C12 PF01088.21 KER33483.1 - 1.4e-57 194.9 0.0 1.6e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 GON PF08685.11 KER33484.1 - 8.5e-48 162.9 0.1 1.5e-46 158.8 0.1 2.7 1 1 0 1 1 1 1 GON domain TSP_1 PF00090.19 KER33484.1 - 1.9e-21 76.0 96.2 7.4e-10 38.9 9.2 13.0 12 1 0 12 12 12 8 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 KER33484.1 - 8.4e-15 55.1 7.0 8.4e-15 55.1 7.0 4.9 3 1 1 4 4 4 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 KER33484.1 - 3.6e-13 50.1 0.0 7.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 KER33484.1 - 1.2e-12 48.1 0.1 9.9e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 KER33484.1 - 9.8e-08 32.6 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KER33484.1 - 1.5e-06 28.2 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KER33484.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like NAD_binding_10 PF13460.6 KER33485.1 - 4e-05 23.6 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF3902 PF13042.6 KER33485.1 - 0.00019 21.0 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3902) MlaA PF04333.13 KER33485.1 - 0.0002 21.1 0.0 0.77 9.4 0.0 2.3 2 0 0 2 2 2 2 MlaA lipoprotein Semialdhyde_dh PF01118.24 KER33485.1 - 0.0004 20.8 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KER33485.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KER33485.1 - 0.028 13.9 0.1 0.039 13.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KER33485.1 - 0.079 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRR_8 PF13855.6 KER33489.1 - 1.5e-27 95.1 12.4 7.1e-17 60.9 2.9 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KER33489.1 - 4.1e-12 46.1 11.1 2.1e-07 31.1 1.2 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KER33489.1 - 2e-08 34.3 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KER33489.1 - 6.9e-07 28.9 0.9 1.1e-06 28.3 0.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRRNT PF01462.18 KER33489.1 - 7e-06 25.6 3.0 1.5e-05 24.5 3.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KER33489.1 - 0.002 18.4 16.5 0.22 12.2 0.1 4.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KER33489.1 - 0.067 13.3 6.4 24 5.3 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Phage_X PF05155.15 KER33489.1 - 0.15 12.5 0.2 3.1 8.3 0.0 2.5 3 0 0 3 3 3 0 Phage X family EGF PF00008.27 KER33490.1 - 4.5e-41 138.7 119.7 1.1e-07 32.0 6.6 9.6 9 0 0 9 9 9 7 EGF-like domain hEGF PF12661.7 KER33490.1 - 2.6e-20 72.2 102.3 8e-06 26.3 4.8 10.4 11 0 0 11 11 11 7 Human growth factor-like EGF Laminin_G_1 PF00054.23 KER33490.1 - 3.4e-17 62.9 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KER33490.1 - 2.9e-16 60.2 0.0 4.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF_2 PF07974.13 KER33490.1 - 1.9e-08 34.5 141.3 0.0067 16.8 13.5 10.3 10 0 0 10 10 10 7 EGF-like domain LRR_8 PF13855.6 KER33490.1 - 2e-08 33.9 5.0 4e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KER33490.1 - 3.8e-06 26.4 1.9 3.8e-06 26.4 1.9 5.3 6 0 0 6 6 6 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 KER33490.1 - 0.00095 19.5 5.3 0.15 12.6 0.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) EGF_3 PF12947.7 KER33490.1 - 0.019 15.2 3.5 0.019 15.2 3.5 10.2 9 3 2 11 11 11 0 EGF domain LRR_1 PF00560.33 KER33490.1 - 4 8.3 4.9 16 6.5 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat PGK PF00162.19 KER33491.1 - 2e-154 514.1 0.3 2.3e-154 513.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S51 PF03575.17 KER33491.1 - 0.13 11.9 0.1 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S51 Pro_isomerase PF00160.21 KER33492.1 - 8.4e-50 169.1 0.2 9.9e-50 168.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HGTP_anticodon PF03129.20 KER33493.1 - 9.2e-18 64.2 0.0 2.1e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 KER33493.1 - 1.2e-09 38.2 1.4 1.2e-09 38.2 1.4 2.3 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 KER33493.1 - 2e-09 37.7 0.0 5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 KER33495.1 - 1.1e-22 80.7 0.0 4.9e-22 78.5 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33495.1 - 1.9e-15 56.9 0.0 9.5e-08 31.6 0.0 4.5 4 1 0 4 4 4 3 Protein tyrosine kinase APH PF01636.23 KER33495.1 - 0.029 14.3 0.2 0.28 11.1 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Activin_recp PF01064.23 KER33495.1 - 0.042 14.9 7.4 0.099 13.7 7.4 1.6 1 0 0 1 1 1 0 Activin types I and II receptor domain Helicase_C PF00271.31 KER33496.1 - 1.1e-21 77.3 0.1 4e-17 62.6 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KER33496.1 - 1.2e-15 57.7 0.0 3e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 KER33496.1 - 1.6e-06 27.9 2.2 4e-06 26.7 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KER33496.1 - 0.037 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KER33496.1 - 0.064 13.1 2.2 0.17 11.7 2.2 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KER33496.1 - 0.091 12.5 1.8 0.27 11.0 1.8 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PDZ PF00595.24 KER33497.1 - 2.5e-20 72.6 0.2 4e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KER33497.1 - 2.6e-19 68.7 0.2 6.7e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 KER33497.1 - 1.3e-11 44.2 0.1 3.4e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER33497.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF2057 PF09829.9 KER33497.1 - 0.0043 17.2 0.2 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) SNase PF00565.17 KER33498.1 - 4.5e-54 181.5 0.0 8e-12 45.6 0.0 5.5 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KER33498.1 - 1.5e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Tudor domain RIF5_SNase_2 PF18189.1 KER33498.1 - 0.16 11.8 0.4 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 TbRIF5 SNase domain 2 Sugar_tr PF00083.24 KER33499.1 - 5.5e-23 81.5 20.5 8.1e-23 81.0 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER33499.1 - 1.3e-16 60.5 26.2 1.3e-16 60.5 26.2 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF2093 PF09866.9 KER33499.1 - 0.013 14.9 0.1 0.043 13.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) PRANC PF09372.10 KER33499.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 PRANC domain BAR_3_WASP_bdg PF10456.9 KER33500.1 - 1.2e-29 103.4 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 KER33500.1 - 9.8e-26 90.0 0.1 2.5e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KER33500.1 - 2.7e-10 39.7 0.0 5.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KER33500.1 - 3.5e-10 39.6 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KER33500.1 - 7.7e-08 31.9 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 KER33500.1 - 0.0093 16.0 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 SH3 domain PI-PLC-X PF00388.19 KER33500.1 - 0.097 12.3 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Gas_vesicle_C PF01304.17 KER33500.1 - 0.14 12.2 1.8 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain PRIMA1 PF16101.5 KER33500.1 - 0.32 11.0 4.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SprT-like PF10263.9 KER33501.1 - 2.9e-24 85.1 0.0 1.5e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 KER33501.1 - 3.5e-09 36.4 5.1 8.8e-09 35.1 5.1 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4694 PF15765.5 KER33501.1 - 0.0013 18.8 0.4 0.0013 18.8 0.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4694) Zn-ribbon_8 PF09723.10 KER33501.1 - 0.047 13.8 1.6 0.13 12.4 1.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Fer4_2 PF12797.7 KER33501.1 - 3.2 8.0 5.0 1.5 9.0 0.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-Sec23_Sec24 PF04810.15 KER33501.1 - 4.8 7.3 6.2 2 8.6 2.6 2.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger LIAS_N PF16881.5 KER33502.1 - 3.8e-25 88.4 0.0 6.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KER33502.1 - 1.2e-10 42.1 0.0 4.5e-10 40.2 0.0 1.9 1 1 1 2 2 2 1 Radical SAM superfamily DUF3716 PF12511.8 KER33503.1 - 0.052 13.6 1.1 0.14 12.2 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Hs1pro-1_N PF07231.12 KER33503.1 - 0.18 11.5 0.2 1.7 8.4 0.1 1.9 1 1 1 2 2 2 0 Hs1pro-1 N-terminus RINGv PF12906.7 KER33504.1 - 2.9e-12 46.5 13.6 5.5e-12 45.6 13.6 1.5 1 0 0 1 1 1 1 RING-variant domain NTF-like PF14540.6 KER33504.1 - 0.096 12.5 0.2 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase-like zf-CSL PF05207.13 KER33504.1 - 0.93 9.3 5.5 2.9 7.7 5.5 1.8 1 1 0 1 1 1 0 CSL zinc finger zf-RING_2 PF13639.6 KER33504.1 - 0.96 9.8 9.0 1.9 8.9 9.0 1.6 1 0 0 1 1 1 0 Ring finger domain AdoMet_MTase PF07757.13 KER33505.1 - 1.1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 KER33505.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER33505.1 - 0.0049 17.6 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER33505.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KER33505.1 - 0.017 15.1 0.8 0.023 14.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KER33505.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KER33505.1 - 0.021 15.5 0.0 0.045 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UL17 PF17640.2 KER33506.1 - 0.021 14.8 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized UL17 Mob1_phocein PF03637.17 KER33507.1 - 1.8e-35 122.5 0.9 2.5e-35 122.0 0.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF1241 PF06840.11 KER33507.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Pam16 PF03656.13 KER33509.1 - 5.7e-27 94.2 1.2 8.6e-27 93.7 1.2 1.2 1 0 0 1 1 1 1 Pam16 Baculo_p33 PF05214.12 KER33509.1 - 0.038 13.8 0.2 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Baculovirus P33 IF3_C PF00707.22 KER33511.1 - 0.00035 20.5 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain zf-rbx1 PF12678.7 KER33512.1 - 9.8e-09 35.4 6.8 2.5e-08 34.1 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KER33512.1 - 5.6e-06 26.3 3.6 5.6e-06 26.3 3.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RanBP PF00641.18 KER33512.1 - 2.1 7.7 8.6 0.41 10.0 0.1 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Chromo PF00385.24 KER33513.1 - 4.9e-13 48.8 0.4 1.7e-12 47.0 0.2 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KER33513.1 - 0.0006 19.9 0.0 0.4 10.8 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain RVT_1 PF00078.27 KER33513.1 - 0.052 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1918 PF08940.11 KER33513.1 - 0.082 12.5 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Homeodomain PF00046.29 KER33514.1 - 6.3e-13 48.4 10.6 1.3e-09 37.7 0.9 2.7 2 0 0 2 2 2 2 Homeodomain Choline_kin_N PF04428.14 KER33514.1 - 0.06 13.0 0.1 49 3.7 0.0 3.3 3 0 0 3 3 3 0 Choline kinase N terminus SapB_2 PF03489.17 KER33515.1 - 0.053 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 2 Ribosomal_L22 PF00237.19 KER33515.1 - 0.084 13.1 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e TROVE PF05731.11 KER33516.1 - 5.1e-91 305.9 2.4 1.6e-90 304.3 2.4 1.8 1 1 0 1 1 1 1 TROVE domain DUF4062 PF13271.6 KER33516.1 - 3.6e-23 81.7 0.0 1.4e-22 79.8 0.0 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF4062) WD40 PF00400.32 KER33516.1 - 2.6e-14 53.4 27.2 0.0042 17.9 0.4 11.3 12 0 0 12 12 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33516.1 - 2.1e-08 34.3 0.1 3.7 7.9 0.0 6.6 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KER33516.1 - 5.4e-05 23.2 0.3 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KER33516.1 - 0.0025 18.2 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KER33516.1 - 0.0075 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain APAF1_C PF17908.1 KER33516.1 - 0.009 16.0 0.5 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 APAF-1 helical domain ABC_tran PF00005.27 KER33516.1 - 0.019 15.5 0.0 0.059 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF1133 PF06576.11 KER33516.1 - 0.02 14.3 0.2 0.22 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) PRK PF00485.18 KER33516.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 KER33516.1 - 0.09 13.0 0.1 0.57 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KER33516.1 - 0.14 11.9 0.2 0.4 10.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Homeodomain PF00046.29 KER33518.1 - 4.5e-20 71.2 3.9 4.5e-20 71.2 3.9 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KER33518.1 - 0.0096 15.8 0.3 0.0096 15.8 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain DUF4407 PF14362.6 KER33518.1 - 0.31 10.4 3.6 0.52 9.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Homez PF11569.8 KER33518.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Ran-binding PF05508.11 KER33519.1 - 0.037 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein DUF2786 PF10979.8 KER33519.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Death_2 PF14786.6 KER33519.1 - 0.14 12.1 0.0 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Tube Death domain HLH PF00010.26 KER33520.1 - 8.9e-20 70.4 0.4 1.5e-19 69.7 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3575 PF12099.8 KER33522.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Anillin PF08174.11 KER33523.1 - 6.7e-15 55.7 0.0 4.4e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 Cell division protein anillin HR1 PF02185.16 KER33523.1 - 0.038 14.1 0.8 0.097 12.8 0.8 1.7 1 0 0 1 1 1 0 Hr1 repeat DUF1635 PF07795.11 KER33524.1 - 0.41 10.5 1.5 0.58 10.0 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Homeodomain PF00046.29 KER33526.1 - 2.6e-20 72.0 4.6 6e-20 70.9 4.6 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KER33526.1 - 0.015 15.1 0.6 0.09 12.7 0.2 2.4 2 0 0 2 2 2 0 Homeobox KN domain CLZ PF16526.5 KER33527.1 - 2.3e-48 162.4 20.1 7.6e-24 83.9 6.1 2.7 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 KER33527.1 - 4.1e-24 84.5 0.0 2.6e-20 72.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 KER33527.1 - 2.6e-06 26.8 0.0 3.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein DUF1858 PF08984.11 KER33527.1 - 0.0003 20.9 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1858) Bacillus_HBL PF05791.11 KER33527.1 - 0.00041 20.2 0.5 1.1 9.1 0.1 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) DUF4164 PF13747.6 KER33527.1 - 0.00058 20.1 2.9 0.86 9.9 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) Trans_reg_C PF00486.28 KER33527.1 - 0.0011 19.0 3.4 1 9.5 0.3 2.6 2 0 0 2 2 2 2 Transcriptional regulatory protein, C terminal ADIP PF11559.8 KER33527.1 - 0.0037 17.4 12.8 0.76 9.8 2.6 3.6 2 2 0 2 2 2 2 Afadin- and alpha -actinin-Binding SOR PF07682.11 KER33527.1 - 0.007 15.3 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 2 Sulphur oxygenase reductase VAPB_antitox PF02697.14 KER33527.1 - 0.013 16.2 4.4 3.6 8.4 0.4 2.7 2 0 0 2 2 2 0 Putative antitoxin DUF4510 PF14971.6 KER33527.1 - 0.014 15.8 0.1 9.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) Trimer_CC PF08954.11 KER33527.1 - 0.015 14.8 1.8 8.9 6.0 0.1 3.4 3 0 0 3 3 3 0 Trimerisation motif Agenet PF05641.12 KER33527.1 - 0.024 15.1 0.1 16 6.1 0.0 2.7 2 0 0 2 2 2 0 Agenet domain Retrotrans_gag PF03732.17 KER33527.1 - 0.055 13.8 1.1 15 5.9 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Ion_trans_2 PF07885.16 KER33527.1 - 0.06 13.3 1.8 0.19 11.7 1.8 1.8 1 0 0 1 1 1 0 Ion channel Myosin_tail_1 PF01576.19 KER33527.1 - 0.072 10.9 13.5 0.49 8.1 3.0 2.1 2 0 0 2 2 2 0 Myosin tail Arrestin_C PF02752.22 KER33527.1 - 0.099 13.1 1.4 16 6.0 0.1 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain TAF6_C PF07571.13 KER33527.1 - 0.17 12.2 0.6 46 4.4 0.0 3.0 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain FliD_C PF07195.12 KER33527.1 - 0.19 11.1 5.3 4.9 6.5 0.5 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.12 KER33527.1 - 0.2 11.7 2.6 20 5.2 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 KER33527.1 - 0.23 11.3 12.5 2.4 8.0 2.5 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Cep57_MT_bd PF06657.13 KER33527.1 - 0.3 11.6 7.4 8 7.0 0.4 3.3 2 2 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KER33527.1 - 0.34 11.0 4.5 37 4.4 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KER33527.1 - 0.34 10.2 12.9 1.9 7.7 2.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 KER33527.1 - 0.37 10.3 2.5 17 4.9 0.2 2.4 2 0 0 2 2 2 0 fzo-like conserved region zf-C4H2 PF10146.9 KER33527.1 - 0.39 11.0 11.5 2.6 8.3 1.8 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Laminin_II PF06009.12 KER33527.1 - 0.77 9.8 4.7 16 5.5 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II BRI3BP PF14965.6 KER33527.1 - 0.84 9.1 4.7 14 5.2 0.4 2.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 PspA_IM30 PF04012.12 KER33527.1 - 1.9 8.0 13.2 4.9 6.7 2.8 2.2 2 0 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.11 KER33527.1 - 3.3 6.5 16.7 4.7 6.0 4.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KER33527.1 - 4.8 7.4 14.3 8 6.6 3.0 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KER33527.1 - 5.7 6.2 14.1 9.4 5.5 2.0 3.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3450) CREPT PF16566.5 KER33527.1 - 6.5 6.9 14.2 13 6.0 3.2 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DLP_helical PF18709.1 KER33527.1 - 7.2 5.7 10.2 11 5.1 1.7 2.3 2 0 0 2 2 2 0 Dynamin-like helical domain SRF-TF PF00319.18 KER33528.1 - 1.3e-23 82.2 0.2 3.3e-23 80.9 0.2 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HSP70 PF00012.20 KER33530.1 - 3e-08 32.3 0.0 3e-08 32.3 0.0 2.9 2 1 1 3 3 3 2 Hsp70 protein DUF5623 PF18536.1 KER33530.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF5623) MnmE_helical PF12631.7 KER33530.1 - 1.3 9.2 8.8 2.3 8.3 8.8 1.4 1 1 0 1 1 1 0 MnmE helical domain Occludin_ELL PF07303.13 KER33530.1 - 2.6 8.8 11.1 1.5 9.5 2.9 3.1 2 1 1 3 3 3 0 Occludin homology domain DUF148 PF02520.17 KER33530.1 - 9 6.5 12.2 1.7 8.8 1.0 3.8 2 2 1 4 4 4 0 Domain of unknown function DUF148 RVT_1 PF00078.27 KER33531.1 - 9.8e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRAM_rpt PF07016.11 KER33534.1 - 0.063 13.1 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor IBN_N PF03810.19 KER33536.1 - 5.6e-06 26.2 0.0 1.9e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_C PF08767.11 KER33536.1 - 0.013 14.6 0.4 0.013 14.6 0.4 2.5 3 0 0 3 3 3 0 CRM1 C terminal MAM33 PF02330.16 KER33537.1 - 1.9e-06 28.0 2.1 2.1e-06 27.9 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3206 PF11472.8 KER33537.1 - 0.021 14.8 0.5 0.025 14.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) RabGAP-TBC PF00566.18 KER33540.1 - 1.1e-10 41.5 6.3 8.5e-09 35.4 0.4 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain His_Phos_2 PF00328.22 KER33542.1 - 9.5e-18 64.7 0.5 1.5e-12 47.6 0.3 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF1664 PF07889.12 KER33544.1 - 0.092 12.8 0.3 0.31 11.1 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.21 KER33545.1 - 7.5e-24 84.5 6.7 2.1e-23 83.0 6.7 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) AAA_assoc_C PF09821.9 KER33546.1 - 0.013 16.0 3.6 0.69 10.5 0.2 2.2 2 0 0 2 2 2 0 C-terminal AAA-associated domain TFR_dimer PF04253.15 KER33546.1 - 0.054 13.6 0.1 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain DUF1690 PF07956.11 KER33546.1 - 0.086 13.3 4.6 0.26 11.7 1.4 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Ripply PF14998.6 KER33546.1 - 2.6 8.8 6.1 0.32 11.7 0.7 2.2 3 1 0 3 3 3 0 Transcription Regulator WD40 PF00400.32 KER33547.1 - 4.8e-33 112.7 28.9 8.4e-06 26.4 0.3 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 KER33547.1 - 1.9e-19 69.2 2.3 3.4e-19 68.4 2.3 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 KER33547.1 - 2.5e-06 27.7 0.1 0.088 13.1 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KER33547.1 - 1.3e-05 24.0 4.2 0.35 9.5 0.1 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KER33547.1 - 2.6e-05 23.7 0.0 0.09 12.1 0.0 2.4 1 1 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 KER33547.1 - 0.00019 21.3 2.3 0.00023 21.0 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER33547.1 - 0.0017 18.2 0.5 0.013 15.4 0.2 2.3 2 0 0 2 2 2 1 F-box domain Nucleoporin_N PF08801.11 KER33547.1 - 0.059 12.1 0.1 2.9 6.5 0.0 2.8 1 1 0 2 2 2 0 Nup133 N terminal like ACPS PF01648.20 KER33549.1 - 1.4e-17 63.8 0.0 2.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF98 PF01947.16 KER33549.1 - 0.014 15.4 0.4 0.022 14.7 0.4 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase DUF2383 PF09537.10 KER33549.1 - 0.038 14.3 0.4 9.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Glyco_transf_8C PF08437.10 KER33549.1 - 0.12 12.5 0.2 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal p450 PF00067.22 KER33550.1 - 0.0033 16.2 0.0 0.0096 14.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 DUF3492 PF11997.8 KER33550.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) YcgR_2 PF12945.7 KER33552.1 - 0.0057 16.8 0.3 1.1 9.5 0.0 2.2 1 1 1 2 2 2 2 Flagellar protein YcgR Mto2_bdg PF12808.7 KER33552.1 - 0.015 15.6 0.3 8.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region VHP PF02209.19 KER33553.1 - 3.4e-14 52.6 0.2 5.7e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Villin headpiece domain Peptidase_M13 PF01431.21 KER33554.1 - 4.6e-08 32.9 0.2 8.2e-05 22.3 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 KER33555.1 - 4.9e-32 112.0 2.3 5.5e-32 111.9 2.3 1.0 1 0 0 1 1 1 1 Peptidase family M13 ZapB PF06005.12 KER33555.1 - 0.0082 16.6 2.6 0.017 15.5 0.1 2.4 3 0 0 3 3 3 1 Cell division protein ZapB WSD PF15613.6 KER33555.1 - 0.082 13.4 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Asp PF00026.23 KER33556.1 - 3.6e-15 56.2 0.0 4.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_M13_N PF05649.13 KER33557.1 - 1.5e-48 166.4 7.1 2.6e-48 165.6 7.1 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KER33557.1 - 4.5e-10 39.5 0.1 1.2e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M13 VWA_2 PF13519.6 KER33558.1 - 9.4e-16 58.4 0.1 8.2e-15 55.4 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KER33558.1 - 1e-11 43.9 14.9 0.00016 21.4 1.9 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KER33558.1 - 2.3e-06 27.6 0.5 4.4e-06 26.7 0.5 1.4 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 KER33558.1 - 0.0013 18.5 1.5 0.0013 18.5 1.5 2.3 2 0 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif His_Phos_2 PF00328.22 KER33559.1 - 3.3e-11 43.2 0.0 0.00011 21.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Herpes_UL82_83 PF05784.11 KER33559.1 - 0.0058 15.5 0.6 2.5 6.9 0.1 2.1 2 0 0 2 2 2 2 Betaherpesvirus UL82/83 protein N terminus His_Phos_2 PF00328.22 KER33560.1 - 1.8e-22 80.2 0.1 1.7e-19 70.4 0.0 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) ToxB_N PF18224.1 KER33560.1 - 0.19 11.7 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 ToxB N-terminal domain UNC-50 PF05216.13 KER33561.1 - 3.4e-72 242.6 20.9 4.6e-72 242.2 20.9 1.1 1 0 0 1 1 1 1 UNC-50 family Pkinase_Tyr PF07714.17 KER33562.1 - 1.1e-36 126.5 0.0 5.2e-36 124.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER33562.1 - 5.5e-26 91.5 0.0 8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KER33562.1 - 1.1e-20 74.0 2.3 5.1e-13 49.4 1.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER33562.1 - 2e-20 72.6 5.0 4.2e-09 36.5 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER33562.1 - 1.2e-18 67.2 3.2 1.5e-11 44.6 0.4 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KER33562.1 - 3.7e-17 61.9 4.2 3.7e-05 24.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KER33562.1 - 8.8e-16 56.4 3.7 0.00091 19.5 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Thioredoxin PF00085.20 KER33563.1 - 5.7e-58 193.3 0.2 3.1e-31 107.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KER33563.1 - 1.2e-21 77.4 0.0 6.4e-15 55.5 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KER33563.1 - 1.7e-14 54.2 1.4 2.6e-07 31.1 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KER33563.1 - 3.6e-13 49.5 0.4 3.5e-06 27.1 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KER33563.1 - 1.4e-09 38.1 0.1 0.011 16.1 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KER33563.1 - 9.1e-07 28.8 0.4 0.035 14.0 0.1 2.5 2 0 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 KER33563.1 - 4.6e-06 26.2 0.2 0.029 13.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KER33563.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_9 PF14595.6 KER33563.1 - 0.0028 17.4 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 KER33563.1 - 0.0046 16.7 1.2 2 8.1 0.1 2.9 3 0 0 3 3 3 2 Redoxin TraF PF13728.6 KER33563.1 - 0.014 15.2 0.3 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Mu-like_Com PF10122.9 KER33563.1 - 0.071 12.6 0.2 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF836 PF05768.14 KER33563.1 - 0.18 12.2 0.0 6.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KER33563.1 - 0.26 11.5 1.8 17 5.7 0.2 2.6 2 0 0 2 2 2 0 Glutaredoxin Pkinase PF00069.25 KER33564.1 - 4.8e-67 226.1 0.0 6.3e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33564.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KER33564.1 - 0.0032 16.3 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KER33564.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KER33564.1 - 0.061 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KER33564.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 KER33564.1 - 0.52 9.8 1.8 3.1 7.3 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL NUDE_C PF04880.13 KER33564.1 - 9.8 6.6 6.9 19 5.7 6.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region An_peroxidase PF03098.15 KER33565.1 - 2.3e-195 650.2 0.0 5.1e-195 649.0 0.0 1.6 1 1 0 1 1 1 1 Animal haem peroxidase Ig_3 PF13927.6 KER33565.1 - 6.6e-20 71.5 0.0 1.2e-10 41.8 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 KER33565.1 - 3.8e-19 68.5 0.0 3.1e-08 33.6 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin I-set domain LRR_8 PF13855.6 KER33565.1 - 6.2e-17 61.1 6.9 1.9e-10 40.3 0.3 2.8 1 1 1 2 2 2 2 Leucine rich repeat Ig_2 PF13895.6 KER33565.1 - 2.3e-11 43.9 0.0 0.00045 20.5 0.0 3.4 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KER33565.1 - 7.2e-11 42.1 0.0 9.3e-05 22.5 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain LRR_4 PF12799.7 KER33565.1 - 1.3e-05 25.5 6.7 0.0096 16.3 0.3 4.2 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRRNT PF01462.18 KER33565.1 - 0.00065 19.3 3.1 0.0022 17.6 3.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain C2-set_2 PF08205.12 KER33565.1 - 0.00067 19.7 0.2 0.06 13.4 0.0 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain LRR_9 PF14580.6 KER33565.1 - 0.0013 18.3 0.1 0.0033 16.9 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat V-set PF07686.17 KER33565.1 - 0.0024 18.0 0.5 3.5 7.8 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain LPP PF04728.13 KER33565.1 - 0.14 12.5 2.0 0.43 11.0 2.0 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper LRR_1 PF00560.33 KER33565.1 - 1.4 9.8 5.8 1.1e+02 4.0 0.2 4.9 5 0 0 5 5 3 0 Leucine Rich Repeat AAA_lid_7 PF17867.1 KER33567.1 - 8.2e-06 26.0 0.1 0.0038 17.4 0.1 3.2 1 1 0 1 1 1 1 Midasin AAA lid domain AAA_5 PF07728.14 KER33567.1 - 0.028 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KER33567.1 - 0.029 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain 7tm_1 PF00001.21 KER33568.1 - 3.7e-19 69.1 1.2 6.7e-19 68.2 1.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KER33568.1 - 1.7e-05 24.3 2.9 3e-05 23.5 2.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1115 PF06544.12 KER33570.1 - 3.3e-13 50.0 0.1 6.5e-13 49.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RWD PF05773.22 KER33570.1 - 9e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF2102 PF09875.9 KER33570.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) TPPII_N PF12583.8 KER33570.1 - 0.15 12.6 0.0 30 5.2 0.0 2.1 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Myb_DNA-binding PF00249.31 KER33572.1 - 3.3e-05 24.0 0.0 0.0055 16.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KER33572.1 - 0.033 14.1 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Amidohydro_1 PF01979.20 KER33573.1 - 4.9e-30 105.0 0.1 9.5e-30 104.1 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KER33573.1 - 5.2e-15 55.9 0.1 1.7e-06 27.8 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KER33573.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 KER33573.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TatD_DNase PF01026.21 KER33573.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 TatD related DNase DEAD PF00270.29 KER33574.1 - 7.8e-17 61.6 0.0 1.7e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER33574.1 - 2.6e-14 53.5 0.0 4.8e-12 46.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KER33574.1 - 6.1e-10 39.7 3.6 2.1e-09 37.9 3.6 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KER33574.1 - 4.4e-05 23.6 0.0 0.00032 20.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Minor_capsid_3 PF12691.7 KER33575.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage HSP70 PF00012.20 KER33576.1 - 3e-81 273.4 0.0 3.8e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 KER33576.1 - 0.00028 20.7 0.1 0.00074 19.3 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Phage_CP76 PF06892.11 KER33576.1 - 0.0014 18.2 0.1 0.027 14.0 0.1 2.2 2 0 0 2 2 2 1 Phage regulatory protein CII (CP76) MreB_Mbl PF06723.13 KER33576.1 - 0.0078 15.1 0.1 0.033 13.0 0.1 1.9 1 1 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 KER33578.1 - 4.2e-52 177.2 0.0 5.8e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KER33578.1 - 0.054 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein TPR_12 PF13424.6 KER33580.1 - 0.071 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3724 PF12521.8 KER33580.1 - 0.38 10.7 4.1 1.4 9.0 4.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) PalH PF08733.10 KER33581.1 - 0.0045 16.0 0.0 0.0049 15.9 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 TMEM100 PF16311.5 KER33581.1 - 0.0064 16.1 4.5 0.0099 15.5 4.5 1.2 1 0 0 1 1 1 1 Transmembrane protein 100 MgtE PF01769.16 KER33581.1 - 0.068 13.5 0.1 0.094 13.1 0.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter DUF3611 PF12263.8 KER33581.1 - 0.51 10.2 3.3 0.72 9.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Ig_3 PF13927.6 KER33582.1 - 1.1e-09 38.7 1.2 1.9e-05 25.2 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 KER33582.1 - 1.3e-05 25.3 0.9 0.0034 17.5 0.1 2.9 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 KER33582.1 - 0.00015 21.7 0.0 0.024 14.7 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER33582.1 - 0.00043 20.6 5.7 0.005 17.2 0.4 3.4 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 KER33582.1 - 0.0024 18.0 0.7 0.0083 16.3 0.2 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 KER33582.1 - 0.0035 17.4 0.5 0.016 15.3 0.4 2.1 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 KER33582.1 - 0.073 13.5 0.9 0.37 11.2 0.3 2.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain Trm112p PF03966.16 KER33582.1 - 0.075 13.6 0.1 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 Trm112p-like protein SKG6 PF08693.10 KER33582.1 - 0.3 10.5 2.7 0.76 9.2 2.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Potyvirid-P3 PF13608.6 KER33585.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF4917 PF16263.5 KER33585.1 - 0.093 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) SDF PF00375.18 KER33586.1 - 7.3e-61 206.3 38.8 5.7e-60 203.4 38.8 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4718 PF15842.5 KER33586.1 - 1.2 8.9 3.3 2.4 7.9 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) TMEM132D_C PF15706.5 KER33586.1 - 2.3 8.1 8.0 0.11 12.3 1.9 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term BTD PF09270.10 KER33587.1 - 1.3e-69 233.3 0.0 2.6e-69 232.3 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 KER33587.1 - 4.6e-49 166.9 0.1 2.4e-48 164.6 0.0 2.3 2 1 0 2 2 2 1 LAG1, DNA binding RP-C_C PF11800.8 KER33590.1 - 0.2 11.7 2.5 0.38 10.8 2.5 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region RA PF00788.23 KER33591.1 - 8.3e-08 32.8 0.4 2.2e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain AhpC-TSA PF00578.21 KER33595.1 - 2.7e-38 130.7 0.0 4.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KER33595.1 - 2.2e-14 53.4 0.0 4.2e-14 52.5 0.0 1.4 1 1 1 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 KER33595.1 - 2.7e-13 49.5 0.0 4.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KER33595.1 - 0.14 12.0 0.1 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 SCO1/SenC EF-hand_7 PF13499.6 KER33597.1 - 3.4e-14 53.0 1.2 9.2e-06 26.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER33597.1 - 6.4e-10 38.2 0.4 0.0066 16.3 0.0 4.0 3 1 2 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KER33597.1 - 7e-10 38.6 2.9 1.3e-05 24.9 0.2 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KER33597.1 - 1.5e-05 24.2 6.3 0.01 15.3 0.0 5.1 6 0 0 6 6 6 1 EF hand EF-hand_9 PF14658.6 KER33597.1 - 5.4e-05 23.4 0.3 0.34 11.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KER33597.1 - 0.0013 18.6 0.1 0.22 11.5 0.0 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KER33597.1 - 0.019 15.8 0.1 0.045 14.6 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain Adenine_glyco PF03352.13 KER33597.1 - 0.044 13.5 0.0 0.26 11.1 0.0 1.8 1 1 1 2 2 2 0 Methyladenine glycosylase EF-hand_14 PF17959.1 KER33597.1 - 0.071 13.5 0.0 4.9 7.6 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 KER33597.1 - 0.15 11.6 2.0 3.1 7.5 0.0 3.4 4 0 0 4 4 4 0 EF hand DIT1_PvcA PF05141.12 KER33597.1 - 0.17 11.3 0.6 0.2 11.1 0.6 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein LSDAT_euk PF18139.1 KER33599.1 - 1.2e-49 169.2 0.0 1.7e-45 155.5 0.0 2.3 2 0 0 2 2 2 2 SLOG in TRPM LSDAT_prok PF18171.1 KER33599.1 - 3.3e-15 55.9 0.0 3.9e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 KER33599.1 - 7.9e-08 31.8 13.1 1.4e-07 31.0 13.1 1.4 1 0 0 1 1 1 1 Ion transport protein FBD PF08387.10 KER33599.1 - 0.13 12.2 0.2 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 FBD Homeodomain PF00046.29 KER33600.1 - 1.4e-22 79.2 4.1 6.5e-22 77.1 4.1 2.2 1 0 0 1 1 1 1 Homeodomain FAM86 PF14904.6 KER33600.1 - 7.7e-05 22.7 0.4 0.7 10.0 0.1 2.8 2 0 0 2 2 2 2 Family of unknown function DUF5508 PF17621.2 KER33600.1 - 0.00057 19.1 0.3 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5508) MMM1 PF10296.9 KER33600.1 - 0.0036 16.4 10.0 0.2 10.6 0.8 2.9 3 0 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 CENP-B_N PF04218.13 KER33600.1 - 0.0075 15.9 0.2 44 3.8 0.1 3.6 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Homeobox_KN PF05920.11 KER33600.1 - 0.088 12.7 0.6 0.37 10.7 0.6 2.1 1 0 0 1 1 1 0 Homeobox KN domain GlutR_dimer PF00745.20 KER33600.1 - 0.096 13.1 0.0 38 4.8 0.0 3.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Myotub-related PF06602.14 KER33601.1 - 3.2e-27 95.4 0.8 9.3e-22 77.4 0.0 4.0 3 1 0 3 3 3 2 Myotubularin-like phosphatase domain AAA_19 PF13245.6 KER33601.1 - 0.13 12.6 0.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4989 PF16379.5 KER33601.1 - 0.13 11.5 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4989) DUF3025 PF11227.8 KER33601.1 - 0.17 11.6 0.3 25 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3025) Peptidase_S51 PF03575.17 KER33601.1 - 0.2 11.3 0.0 29 4.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S51 RRM_1 PF00076.22 KER33602.1 - 3.4e-17 62.0 0.0 4.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KER33602.1 - 4.4e-05 23.3 5.7 7.4e-05 22.6 5.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KER33602.1 - 0.00017 21.4 0.2 0.00027 20.8 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 KER33602.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 KER33602.1 - 0.0029 17.3 1.7 0.0047 16.6 1.7 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 KER33602.1 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KER33602.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Occluded RNA-recognition motif EF-hand_1 PF00036.32 KER33604.1 - 1.7e-17 61.6 1.3 1.3e-05 24.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KER33604.1 - 8.8e-17 61.3 2.1 1.5e-13 51.0 0.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KER33604.1 - 4.3e-14 51.2 2.5 0.0024 17.7 0.0 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 KER33604.1 - 1.1e-10 40.5 3.2 7.6e-05 22.0 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KER33604.1 - 1.7e-08 34.2 1.0 0.006 16.4 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KER33604.1 - 1.8e-05 24.6 1.0 0.033 14.2 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KER33604.1 - 0.0011 19.3 0.2 0.052 13.9 0.2 2.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 KER33604.1 - 0.016 15.1 0.0 3.6 7.6 0.0 2.6 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Dockerin_1 PF00404.18 KER33604.1 - 0.15 12.3 0.2 0.73 10.1 0.2 2.1 1 1 0 1 1 1 0 Dockerin type I domain cNMP_binding PF00027.29 KER33606.1 - 2e-44 149.5 0.2 2.6e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CRM1_repeat_2 PF18784.1 KER33606.1 - 0.064 12.9 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 LRR_8 PF13855.6 KER33608.1 - 8.2e-11 41.5 4.1 9.7e-08 31.7 0.1 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRRNT PF01462.18 KER33608.1 - 2.3e-05 23.9 5.3 8e-05 22.2 5.3 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 KER33608.1 - 0.00056 20.1 1.0 3.1 8.7 0.1 4.7 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 KER33608.1 - 0.0027 18.1 3.8 0.41 11.1 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Strep_pep PF14404.6 KER33609.1 - 0.042 14.1 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species CP2 PF04516.15 KER33610.1 - 4.2e-45 153.8 0.0 7e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor SAM_3 PF18016.1 KER33610.1 - 2.1e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KER33610.1 - 0.0094 16.4 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KER33610.1 - 0.032 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ion_trans PF00520.31 KER33611.1 - 6.8e-45 153.2 15.6 8.9e-45 152.8 15.6 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER33611.1 - 1.2e-27 96.1 0.1 2.4e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER33611.1 - 3.7e-14 52.4 6.0 3.7e-14 52.4 6.0 2.4 2 0 0 2 2 2 1 Ion channel BTB_3 PF16017.5 KER33611.1 - 0.051 13.7 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain PKD_channel PF08016.12 KER33611.1 - 0.064 11.9 11.5 0.075 11.7 7.9 2.4 1 1 0 2 2 2 0 Polycystin cation channel Lig_chan PF00060.26 KER33611.1 - 0.86 9.4 6.6 1.8 8.4 1.3 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel LRR19-TM PF15176.6 KER33611.1 - 0.99 9.4 6.3 2.8 8.0 0.0 3.5 4 0 0 4 4 4 0 Leucine-rich repeat family 19 TM domain U1snRNP70_N PF12220.8 KER33612.1 - 4.3e-26 91.4 5.9 4.3e-26 91.4 5.9 2.2 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KER33612.1 - 5.8e-17 61.3 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KER33612.1 - 0.051 13.8 0.3 0.12 12.6 0.3 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase_Tyr PF07714.17 KER33614.1 - 1.2e-44 152.6 0.0 2.4e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KER33614.1 - 6.9e-23 81.3 0.0 3.4e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KER33614.1 - 0.00066 20.2 1.4 0.0081 16.7 0.1 3.6 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 KER33614.1 - 0.0018 18.3 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 KER33614.1 - 0.15 12.4 3.4 1.8 8.9 0.1 4.3 5 0 0 5 5 5 0 Immunoglobulin domain zf-MIZ PF02891.20 KER33615.1 - 0.31 10.8 3.4 20 5.0 0.3 3.3 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Homeodomain PF00046.29 KER33617.1 - 4e-11 42.6 1.6 8.5e-11 41.5 1.6 1.6 1 0 0 1 1 1 1 Homeodomain Ntox28 PF15605.6 KER33619.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 28 LIM PF00412.22 KER33620.1 - 2.1e-31 107.9 35.7 1.4e-11 44.5 6.0 3.3 3 0 0 3 3 3 3 LIM domain STATa_Ig PF18214.1 KER33620.1 - 0.062 13.3 0.2 4.3 7.4 0.1 2.5 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain Auxin_repressed PF05564.12 KER33620.1 - 0.22 12.2 10.8 0.38 11.4 0.8 3.5 3 1 1 4 4 4 0 Dormancy/auxin associated protein DUF2175 PF09943.9 KER33620.1 - 0.33 11.3 1.7 1.1 9.6 1.7 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.9 KER33620.1 - 0.49 10.9 4.5 1.7 9.2 4.5 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Dicty_REP PF05086.12 KER33620.1 - 1.9 6.3 4.2 3.5 5.5 4.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Strep_pep PF14404.6 KER33621.1 - 0.018 15.3 0.0 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species Hormone_2 PF00123.20 KER33621.1 - 0.59 10.1 9.9 2.2 8.2 2.0 2.4 2 0 0 2 2 2 0 Peptide hormone DUF5607 PF18355.1 KER33622.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Metallophos PF00149.28 KER33624.1 - 0.12 12.8 0.2 1.2 9.5 0.2 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Ccdc124 PF06244.12 KER33632.1 - 2e-30 106.0 31.3 1.7e-26 93.3 31.3 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KER33632.1 - 0.0024 18.3 0.3 0.0024 18.3 0.3 2.6 2 1 0 3 3 3 1 HMG (high mobility group) box CHDNT PF08073.12 KER33632.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain FOXP-CC PF16159.5 KER33632.1 - 5.6 7.7 7.2 1.7 9.3 2.3 2.6 2 1 0 2 2 2 0 FOXP coiled-coil domain Pkinase PF00069.25 KER33637.1 - 1e-70 238.2 0.0 1.6e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33637.1 - 2e-36 125.6 0.0 3.1e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.27 KER33637.1 - 1.2e-23 83.9 0.0 5.6e-11 42.4 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glutaredoxin PF00462.24 KER33637.1 - 5.6e-15 55.3 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin PH PF00169.29 KER33637.1 - 2.4e-13 50.5 0.1 5.1e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KER33637.1 - 1.4e-07 31.1 0.0 2.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 KER33637.1 - 0.071 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 KER33637.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF5379 PF17350.2 KER33637.1 - 0.17 12.2 0.0 0.51 10.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5379) PH_11 PF15413.6 KER33637.1 - 0.63 10.5 3.2 0.84 10.1 0.1 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Snurportin1 PF11538.8 KER33639.1 - 1.8e-06 28.0 0.7 1.8e-06 28.0 0.7 2.1 2 0 0 2 2 2 1 Snurportin1 IBB PF01749.20 KER33639.1 - 0.003 18.0 1.2 0.0059 17.0 1.2 1.5 1 0 0 1 1 1 1 Importin beta binding domain Rhabdo_M1 PF03342.13 KER33639.1 - 0.078 12.3 0.5 0.12 11.7 0.5 1.2 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) NAP PF00956.18 KER33640.1 - 1.2e-94 316.4 4.6 1.2e-94 316.4 4.6 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Pes-10 PF07149.11 KER33640.1 - 0.085 11.9 7.4 0.17 10.9 7.4 1.4 1 0 0 1 1 1 0 Pes-10 Stn1_C PF12659.7 KER33640.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH NOA36 PF06524.12 KER33640.1 - 0.33 10.2 12.1 0.69 9.2 12.1 1.5 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KER33640.1 - 0.37 8.8 4.6 0.51 8.3 4.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KER33640.1 - 0.75 8.0 12.3 1.2 7.4 12.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KER33640.1 - 2.9 6.0 16.1 4.7 5.3 16.1 1.3 1 0 0 1 1 1 0 Nop14-like family Epimerase PF01370.21 KER33641.1 - 1.1e-08 34.8 0.0 2.2e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KER33641.1 - 1.3e-08 35.0 0.0 5.5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KER33641.1 - 1.2e-05 24.4 0.0 0.005 15.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KER33641.1 - 2.7e-05 23.4 0.0 0.00025 20.3 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KER33641.1 - 3.7e-05 23.4 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KER33641.1 - 0.045 12.9 0.4 7 5.7 0.1 2.8 2 1 1 3 3 3 0 Male sterility protein DUF5481 PF17578.2 KER33641.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5481) DASH_Dad1 PF08649.10 KER33642.1 - 0.026 14.7 1.8 1.3 9.2 0.2 3.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 TMP_2 PF06791.13 KER33642.1 - 0.52 10.0 9.2 1.5 8.4 2.0 2.9 2 1 1 3 3 3 0 Prophage tail length tape measure protein Sec1 PF00995.23 KER33643.1 - 3.6e-130 435.9 0.9 4.1e-130 435.7 0.9 1.0 1 0 0 1 1 1 1 Sec1 family SPACA9 PF15120.6 KER33643.1 - 0.026 14.3 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF438 PF04282.13 KER33643.1 - 4.9 7.2 5.8 2.5 8.1 0.1 3.4 5 0 0 5 5 5 0 Family of unknown function (DUF438) CPSF73-100_C PF11718.8 KER33644.1 - 8.7e-39 133.3 0.1 4.3e-38 131.0 0.1 1.9 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KER33644.1 - 8.4e-36 122.6 0.0 1.4e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KER33644.1 - 5.2e-19 67.9 0.0 1.2e-18 66.7 0.0 1.7 1 1 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Pkinase PF00069.25 KER33645.1 - 1.7e-60 204.6 0.0 2.5e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33645.1 - 1.3e-29 103.2 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KER33645.1 - 0.00055 19.0 1.9 0.0046 16.0 0.3 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KER33645.1 - 0.00068 19.6 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER33645.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amidohydro_1 PF01979.20 KER33646.1 - 9.2e-11 41.6 0.0 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KER33646.1 - 2.1e-05 24.2 0.1 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Myosin_head PF00063.21 KER33648.1 - 2.2e-39 135.2 0.0 1.5e-14 53.2 0.0 4.8 5 0 0 5 5 5 4 Myosin head (motor domain) TPR_MLP1_2 PF07926.12 KER33648.1 - 0.00039 20.5 17.0 0.00039 20.5 17.0 6.9 3 1 2 6 6 6 3 TPR/MLP1/MLP2-like protein CbiA PF01656.23 KER33648.1 - 0.09 12.8 0.0 0.09 12.8 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GIT_CC PF16559.5 KER33648.1 - 5.6 6.9 17.1 5.5 6.9 0.3 4.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor MAP65_ASE1 PF03999.12 KER33650.1 - 5.4e-49 167.4 46.0 2.6e-38 132.1 26.6 2.0 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) ASL_C PF08328.11 KER33650.1 - 0.00032 20.8 2.3 1 9.5 0.2 3.2 2 2 0 2 2 2 2 Adenylosuccinate lyase C-terminal Protoglobin PF11563.8 KER33650.1 - 0.00052 20.0 0.2 1.9 8.4 0.0 3.0 3 0 0 3 3 3 2 Protoglobin DMAP1_like PF17024.5 KER33650.1 - 0.0076 16.4 2.8 3.3 7.9 0.2 2.7 2 0 0 2 2 2 2 Putative DMAP1-like Abi_C PF14355.6 KER33650.1 - 0.017 15.2 0.3 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Abortive infection C-terminus WD40_alt PF14077.6 KER33650.1 - 0.048 13.5 0.7 21 5.1 0.1 3.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif Pox_A_type_inc PF04508.12 KER33650.1 - 0.11 12.4 13.3 0.49 10.3 0.2 3.8 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat DUF1192 PF06698.11 KER33650.1 - 0.73 9.9 5.4 59 3.8 0.2 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 KER33650.1 - 0.84 9.7 16.8 2 8.5 0.3 5.6 7 2 1 8 8 8 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 KER33650.1 - 1.6 8.4 21.2 0.5 10.0 0.4 4.8 2 2 1 5 5 5 0 SWI5-dependent HO expression protein 3 Coat_F PF07875.12 KER33650.1 - 3 8.1 5.2 52 4.2 0.1 3.5 4 0 0 4 4 4 0 Coat F domain MPS2 PF17060.5 KER33650.1 - 4 6.6 15.8 2.4 7.3 1.0 3.3 3 1 0 3 3 3 0 Monopolar spindle protein 2 Spore_III_AB PF09548.10 KER33650.1 - 6.1 6.9 19.6 2.2 8.4 1.8 4.4 5 1 0 5 5 5 0 Stage III sporulation protein AB (spore_III_AB) Ion_trans PF00520.31 KER33651.1 - 2.7e-46 157.8 11.7 5.3e-46 156.8 11.7 1.5 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER33651.1 - 2e-27 95.3 0.1 5.7e-27 93.9 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER33651.1 - 8.4e-14 51.3 5.9 8.4e-14 51.3 5.9 2.4 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 KER33651.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain eIF-5a PF01287.20 KER33651.1 - 0.22 11.6 0.7 0.77 9.9 0.1 2.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PseudoU_synth_2 PF00849.22 KER33652.1 - 2.7e-19 69.8 0.0 4.9e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase RVT_1 PF00078.27 KER33652.1 - 0.00044 19.8 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RCC1 PF00415.18 KER33653.1 - 1.5e-39 134.3 6.3 2.2e-14 53.8 0.0 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KER33653.1 - 8.4e-22 76.4 22.1 2.1e-09 36.9 3.2 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF1921 PF09081.10 KER33653.1 - 0.043 14.0 0.2 1.2 9.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Kelch_4 PF13418.6 KER33653.1 - 0.047 13.7 0.6 0.51 10.4 0.1 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain CN_hydrolase PF00795.22 KER33654.1 - 1.7e-22 80.1 0.0 2.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KER33654.1 - 8.8e-22 77.4 0.0 3.4e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KER33654.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase HEM4 PF02602.15 KER33655.1 - 2.7e-32 112.0 0.0 3.1e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD EF-hand_7 PF13499.6 KER33656.1 - 2.4e-18 66.3 0.0 1.1e-17 64.3 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KER33656.1 - 1.3e-15 55.7 0.3 5.8e-07 28.6 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KER33656.1 - 5.7e-13 47.7 0.4 5e-05 22.9 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 KER33656.1 - 8e-13 47.3 0.2 1e-05 24.8 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KER33656.1 - 2.1e-07 30.7 0.3 2.8e-06 27.1 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain pair Dockerin_1 PF00404.18 KER33656.1 - 0.00035 20.7 0.8 0.0022 18.2 0.9 2.1 1 1 0 1 1 1 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KER33656.1 - 0.00067 20.0 0.0 0.31 11.4 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KER33656.1 - 0.028 14.4 0.1 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand FG-GAP PF01839.23 KER33656.1 - 0.76 10.0 2.6 3 8.1 0.3 2.2 2 0 0 2 2 2 0 FG-GAP repeat HMG_box_2 PF09011.10 KER33657.1 - 0.0052 17.4 3.2 0.0052 17.4 3.2 1.7 2 0 0 2 2 2 1 HMG-box domain Nas2_N PF18265.1 KER33660.1 - 9.8e-29 99.1 0.1 1.7e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KER33660.1 - 5.3e-07 29.4 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER33660.1 - 1.9e-05 25.0 0.0 4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER33660.1 - 0.00062 20.0 0.0 0.002 18.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain SLX9 PF15341.6 KER33660.1 - 0.19 12.1 0.4 1.3 9.4 0.1 2.0 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 BTB_2 PF02214.22 KER33663.1 - 4.2e-20 71.9 0.1 7.8e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 KER33663.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain VEK-30 PF12107.8 KER33663.1 - 1.5 8.8 4.2 3.1 7.8 4.2 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway p25-alpha PF05517.12 KER33665.1 - 1.1e-44 152.3 4.6 1.2e-44 152.2 4.6 1.0 1 0 0 1 1 1 1 p25-alpha F-box-like PF12937.7 KER33666.1 - 4.4e-14 52.1 1.2 4.4e-14 52.1 1.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER33666.1 - 2.1e-10 40.2 2.5 4.3e-10 39.2 2.5 1.6 1 0 0 1 1 1 1 F-box domain CdhD PF03599.16 KER33666.1 - 0.035 12.8 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit F-box-like PF12937.7 KER33667.1 - 1e-13 50.9 0.2 1e-13 50.9 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KER33667.1 - 5.6e-08 32.5 0.1 1.9e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain SPRY PF00622.28 KER33668.1 - 1.3e-13 51.1 0.0 2.7e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 KER33668.1 - 2.3e-07 30.8 4.8 2.3e-07 30.8 4.8 4.4 4 1 0 4 4 4 1 B-box zinc finger fn3 PF00041.21 KER33668.1 - 1.9e-05 24.9 0.0 5.2e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain zf-RING_UBOX PF13445.6 KER33668.1 - 0.00015 21.7 4.8 0.00015 21.7 4.8 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KER33668.1 - 0.00048 20.2 7.7 0.00048 20.2 7.7 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KER33668.1 - 0.0027 17.6 4.3 0.0027 17.6 4.3 3.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KER33668.1 - 0.0043 16.9 4.4 0.0043 16.9 4.4 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SPX PF03105.19 KER33668.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 SPX domain zf-RING_5 PF14634.6 KER33668.1 - 0.0079 16.1 2.7 0.0079 16.1 2.7 4.3 4 0 0 4 4 4 1 zinc-RING finger domain DUF3053 PF11254.8 KER33668.1 - 0.038 13.6 0.6 0.068 12.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) zf_PR_Knuckle PF18445.1 KER33668.1 - 5 7.0 7.4 1.8 8.4 1.5 3.2 3 0 0 3 3 3 0 PR zinc knuckle motif Mito_carr PF00153.27 KER33669.1 - 1.2e-35 121.3 0.0 7.3e-18 64.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Sulfotransfer_1 PF00685.27 KER33669.1 - 0.07 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain HLH PF00010.26 KER33671.1 - 0.00099 19.0 1.9 0.0021 17.9 1.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3617 PF12276.8 KER33671.1 - 0.035 14.4 0.2 0.082 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) HTH_32 PF13565.6 KER33671.1 - 0.038 14.6 1.6 0.078 13.6 1.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain CSTF_C PF14304.6 KER33671.1 - 3.1 7.5 7.5 0.12 12.0 1.3 2.0 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal HLH PF00010.26 KER33673.1 - 1.3e-06 28.3 0.8 2.8e-06 27.2 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KER33674.1 - 4.6e-05 23.3 0.5 4.6e-05 23.3 0.5 2.1 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF4794 PF16042.5 KER33674.1 - 1.3 10.0 6.2 2 9.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4794) HLH PF00010.26 KER33676.1 - 0.0096 15.9 0.5 0.016 15.2 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rer1 PF03248.13 KER33677.1 - 2.1e-35 122.0 0.8 3.2e-35 121.4 0.8 1.3 1 0 0 1 1 1 1 Rer1 family Tmemb_18A PF09771.9 KER33677.1 - 0.052 13.9 0.2 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 188 DUF1980 PF09323.10 KER33677.1 - 0.17 11.8 3.4 0.32 10.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Prefoldin_2 PF01920.20 KER33678.1 - 2.7e-12 46.6 8.4 5.8e-12 45.5 8.4 1.5 1 1 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KER33678.1 - 4.8 7.7 9.4 0.67 10.4 2.1 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) LRR_4 PF12799.7 KER33679.1 - 7.2e-07 29.4 3.6 0.00013 22.2 1.6 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KER33679.1 - 2.8e-06 27.0 2.3 0.0009 19.0 2.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KER33679.1 - 0.0054 17.1 1.3 7 7.6 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.6 KER33679.1 - 0.0058 16.2 0.5 0.0067 15.9 0.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 KER33679.1 - 0.14 12.2 3.8 5.3 7.3 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat Spc7 PF08317.11 KER33681.1 - 0.31 9.9 6.0 0.51 9.2 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 KER33681.1 - 4 7.9 7.2 9.9 6.6 7.2 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Dpy-30 PF05186.13 KER33683.1 - 1.2e-10 40.8 0.7 7.6e-10 38.3 0.0 2.6 2 1 1 3 3 3 1 Dpy-30 motif RIIa PF02197.17 KER33683.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.6 KER33684.1 - 3.4e-20 72.3 6.5 2.3e-07 31.2 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 KER33684.1 - 1.1e-15 57.2 2.4 3.6e-06 26.7 0.1 5.4 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 KER33684.1 - 1.6e-14 52.2 3.2 9.7e-07 27.9 0.2 5.3 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KER33684.1 - 2.3e-12 45.8 7.1 0.00028 20.6 0.2 6.5 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.6 KER33684.1 - 8.5e-08 31.4 9.3 9.9e-06 24.8 0.1 4.6 6 0 0 6 6 6 2 EF hand GlnD_UR_UTase PF08335.11 KER33684.1 - 0.00062 19.9 0.1 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 GlnD PII-uridylyltransferase SPARC_Ca_bdg PF10591.9 KER33684.1 - 0.0015 18.9 1.7 1.4 9.3 0.1 3.6 2 1 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region TPR_2 PF07719.17 KER33685.1 - 1.6e-10 40.3 1.4 0.026 14.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER33685.1 - 1.5e-08 35.0 0.9 0.0039 17.7 0.1 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KER33685.1 - 2.8e-08 33.9 3.5 0.038 14.8 0.0 5.2 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KER33685.1 - 7.1e-05 23.4 0.5 0.084 13.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 KER33685.1 - 0.00097 18.2 1.2 0.083 11.8 0.2 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KER33685.1 - 0.0017 17.7 2.6 0.0027 17.0 2.6 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KER33685.1 - 0.003 17.7 0.0 14 6.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KER33685.1 - 0.0047 16.6 0.9 5.7 6.7 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KER33685.1 - 0.016 15.0 0.8 1 9.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KER33685.1 - 0.051 13.3 0.0 12 5.6 0.0 2.4 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 SafA PF17073.5 KER33687.1 - 0.62 10.0 2.0 1.4 9.0 2.0 1.5 1 0 0 1 1 1 0 Two-component-system connector protein Actin PF00022.19 KER33688.1 - 2.2e-149 497.6 0.0 7.3e-149 495.8 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER33689.1 - 7.6e-150 499.0 0.0 2.5e-149 497.3 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KER33690.1 - 2.7e-150 500.5 0.0 9e-150 498.8 0.0 1.7 1 1 0 1 1 1 1 Actin FAM92 PF06730.11 KER33691.1 - 1.8e-18 66.8 2.6 2.8e-18 66.2 2.6 1.2 1 0 0 1 1 1 1 FAM92 protein Rap1_C PF11626.8 KER33691.1 - 0.093 12.8 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HSP20 PF00011.21 KER33692.1 - 7.5e-24 83.8 0.0 2.1e-14 53.5 0.1 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KER33692.1 - 5.3e-05 22.7 0.0 0.00026 20.5 0.0 2.1 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Vac_Fusion PF02346.16 KER33692.1 - 0.073 12.7 0.1 0.25 11.0 0.1 1.9 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 BB_PF PF18063.1 KER33692.1 - 1.2 8.7 4.2 2.5 7.6 4.2 1.5 1 0 0 1 1 1 0 Beta barrel Pore-forming domain Ion_trans PF00520.31 KER33694.1 - 2.5e-38 131.7 14.9 3.6e-38 131.2 14.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER33694.1 - 3.6e-24 84.9 0.0 8.5e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER33694.1 - 1.3e-11 44.3 8.2 1.3e-11 44.3 8.2 2.4 3 0 0 3 3 3 1 Ion channel Shal-type PF11601.8 KER33694.1 - 1.1e-09 37.7 4.3 2.4e-09 36.6 4.3 1.6 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 KER33694.1 - 3.8e-06 27.0 0.0 1.5e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 KER33694.1 - 1.3 7.6 9.9 2.6 6.6 9.9 1.4 1 1 0 1 1 1 0 Polycystin cation channel ARPC4 PF05856.12 KER33695.1 - 7.8e-80 266.3 4.7 8.6e-80 266.2 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 KER33695.1 - 0.0057 16.8 0.1 0.01 15.9 0.1 1.4 1 1 0 1 1 1 1 Sm_like domain HTH_Tnp_Tc3_1 PF11427.8 KER33695.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase Glyco_transf_8 PF01501.20 KER33696.1 - 2.4e-05 24.0 0.1 3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Sulfotransfer_3 PF13469.6 KER33698.1 - 1.2e-26 94.5 0.0 2.2e-26 93.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KER33698.1 - 7.6e-06 25.6 0.2 1.6e-05 24.5 0.2 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Myelin_PLP PF01275.19 KER33699.1 - 9.1e-09 35.5 10.4 3.5e-06 27.1 6.9 2.2 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) DUF3206 PF11472.8 KER33699.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF3810 PF12725.7 KER33699.1 - 0.084 12.2 0.5 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LIM PF00412.22 KER33701.1 - 3.1e-07 30.5 10.1 5.6e-07 29.7 10.1 1.4 1 0 0 1 1 1 1 LIM domain Phage_Gp17 PF17549.2 KER33701.1 - 0.27 11.2 4.4 0.48 10.4 4.4 1.3 1 0 0 1 1 1 0 Gene Product 17 DUF2318 PF10080.9 KER33701.1 - 0.61 10.2 4.7 2.4 8.4 1.5 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) NOA36 PF06524.12 KER33701.1 - 2.5 7.3 11.5 0.037 13.4 0.7 2.4 2 0 0 2 2 2 0 NOA36 protein zf-C3HC4_2 PF13923.6 KER33701.1 - 3.5 7.6 7.9 0.24 11.3 1.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PPP4R2 PF09184.11 KER33702.1 - 4.9e-29 101.8 2.9 4.9e-29 101.8 2.9 3.4 2 1 0 2 2 2 1 PPP4R2 Peptidase_M32 PF02074.15 KER33703.1 - 5.2 5.7 10.5 15 4.2 9.6 1.9 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase SMK-1 PF04802.15 KER33704.1 - 1.7e-57 194.3 5.1 1.7e-57 194.3 5.1 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RSV_NS2 PF03113.14 KER33704.1 - 0.15 12.1 0.7 0.33 11.0 0.7 1.5 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Importin_rep_4 PF18808.1 KER33704.1 - 7.2 7.0 10.9 10 6.5 1.9 3.9 4 0 0 4 4 4 0 Importin repeat ANTH PF07651.16 KER33705.1 - 9.2e-40 136.4 0.4 1.1e-35 123.0 0.2 2.2 1 1 1 2 2 2 2 ANTH domain T-box PF00907.22 KER33707.1 - 1.6e-53 181.7 0.2 7.7e-51 173.0 0.0 2.7 2 1 0 2 2 2 1 T-box SPATA6 PF14909.6 KER33708.1 - 0.00087 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 zf-C2H2 PF00096.26 KER33710.1 - 2.5e-09 37.1 21.6 0.00073 19.9 2.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER33710.1 - 5.7e-05 23.6 19.0 0.037 14.9 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER33710.1 - 0.00019 21.7 1.9 0.00019 21.7 1.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KER33710.1 - 0.0064 16.9 0.6 0.0064 16.9 0.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KER33710.1 - 0.014 15.7 1.4 0.014 15.7 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KER33710.1 - 0.017 15.8 2.0 2.4 8.8 0.2 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KER33710.1 - 0.048 14.0 7.9 0.89 9.9 1.9 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon IBR PF01485.21 KER33710.1 - 2.1 8.6 6.3 24 5.2 6.3 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DSPc PF00782.20 KER33711.1 - 7.7e-28 96.9 0.0 1e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KER33711.1 - 0.026 14.8 0.1 0.068 13.5 0.1 1.8 1 1 0 1 1 1 0 Rit1 DUSP-like domain CsgA PF17334.2 KER33713.1 - 0.057 14.2 0.0 22 5.9 0.0 2.3 2 0 0 2 2 2 0 Minor curli fiber component A DUF5329 PF17263.2 KER33713.1 - 0.13 12.5 0.2 31 4.9 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5329) zinc_ribbon_9 PF14369.6 KER33713.1 - 1.1 9.6 5.0 69 3.8 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon Endonuclease_NS PF01223.23 KER33714.1 - 7.4e-47 160.1 0.0 8.5e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease IL13 PF03487.13 KER33718.1 - 0.011 15.5 0.1 0.89 9.3 0.0 2.0 1 1 1 2 2 2 0 Interleukin-13 zf-C4 PF00105.18 KER33720.1 - 1.7e-30 105.2 13.6 3.5e-30 104.3 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 KER33720.1 - 1.5e-10 41.0 0.1 2.3e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor YbfN PF13982.6 KER33720.1 - 0.13 12.6 0.3 0.46 10.8 0.3 1.9 1 0 0 1 1 1 0 YbfN-like lipoprotein Fimbrial_CS1 PF04449.12 KER33720.1 - 1.2 9.2 7.6 0.69 10.0 3.6 2.7 2 0 0 2 2 2 0 CS1 type fimbrial major subunit KH_1 PF00013.29 KER33729.1 - 1.1e-23 82.8 0.6 4e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 KER33729.1 - 1e-07 31.7 3.4 0.00012 21.8 0.5 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 KER33729.1 - 0.0001 22.1 0.8 0.46 10.4 0.1 2.5 2 0 0 2 2 2 2 KH domain SLS PF14611.6 KER33729.1 - 0.047 13.5 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF3602 PF12223.8 KER33729.1 - 0.059 14.0 2.3 0.17 12.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) KH_5 PF13184.6 KER33729.1 - 0.13 12.4 2.3 12 6.0 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain MARVEL PF01284.23 KER33730.1 - 7.5e-24 84.4 8.6 1e-23 84.0 8.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_3_6 PF07332.11 KER33730.1 - 0.016 15.2 1.2 0.049 13.7 0.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3566 PF12089.8 KER33730.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) RVT_1 PF00078.27 KER33731.1 - 0.0018 17.8 0.0 0.84 9.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) LicD PF04991.13 KER33732.1 - 5e-14 53.0 0.1 1.1e-07 32.3 0.1 2.3 1 1 1 2 2 2 2 LicD family NTP_transf_2 PF01909.23 KER33732.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain zinc_ribbon_6 PF14599.6 KER33735.1 - 0.048 13.7 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon PI3_PI4_kinase PF00454.27 KER33737.1 - 2.5e-31 109.4 0.1 4e-29 102.2 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KER33737.1 - 1.4e-22 80.0 0.0 3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ribosomal_S6e PF01092.19 KER33739.1 - 1.3e-46 157.6 0.1 2.6e-46 156.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Methyltransf_5 PF01795.19 KER33740.1 - 9.2e-84 281.6 0.1 4e-41 141.5 0.0 3.1 2 1 0 3 3 3 3 MraW methylase family HHH_3 PF12836.7 KER33740.1 - 0.012 15.9 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif KRAP_IP3R_bind PF14722.6 KER33740.1 - 0.018 14.8 0.0 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Methyltr_RsmB-F PF01189.17 KER33740.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KER33740.1 - 0.053 14.2 0.0 0.21 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MRP-L46 PF11788.8 KER33741.1 - 2.7e-05 24.9 0.2 4.5e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Tcp10_C PF07202.13 KER33742.1 - 2.9e-60 203.2 2.0 2.9e-60 203.2 0.3 1.9 2 0 0 2 2 2 1 T-complex protein 10 C-terminus Exo_endo_phos_2 PF14529.6 KER33742.1 - 1.8e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER33742.1 - 5.8e-05 22.7 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_MLP1_2 PF07926.12 KER33742.1 - 0.096 12.7 19.1 0.32 11.1 19.1 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TetR_C_30 PF17939.1 KER33742.1 - 0.14 12.3 3.0 2.8 8.2 0.9 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Fib_alpha PF08702.10 KER33742.1 - 0.56 10.4 8.9 1.5 9.0 3.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KER33742.1 - 0.87 8.0 3.7 1.4 7.4 3.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF5082 PF16888.5 KER33742.1 - 2.1 8.6 11.8 2.9 8.2 0.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KER33742.1 - 4 6.7 16.4 24 4.2 16.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Trypsin PF00089.26 KER33744.1 - 1.3e-64 218.1 0.0 1.8e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 KER33744.1 - 3.5e-20 72.4 0.8 2.1e-14 53.8 0.1 2.5 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 KER33744.1 - 0.00035 20.9 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 KER33744.1 - 0.00083 20.3 0.0 0.0016 19.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF5605 PF18310.1 KER33744.1 - 0.063 13.2 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) GLTP PF08718.11 KER33745.1 - 1.7e-18 67.4 1.3 2.1e-18 67.0 1.3 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) ACP53EA PF06313.11 KER33745.1 - 0.042 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Drosophila ACP53EA protein Pkinase PF00069.25 KER33747.1 - 2.7e-66 223.6 0.0 4.4e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33747.1 - 1.1e-45 156.0 0.1 1.5e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KER33747.1 - 4.5e-10 39.7 0.0 8.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KER33747.1 - 2.1e-09 37.1 0.0 6.6e-08 32.2 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KER33747.1 - 7.7e-08 31.5 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KER33747.1 - 0.0098 14.9 0.4 0.029 13.3 0.4 1.6 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KER33747.1 - 0.011 15.4 0.0 0.47 10.1 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KER33747.1 - 0.13 12.2 0.0 3 7.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KER33748.1 - 1.4e-57 195.1 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33748.1 - 8.6e-43 146.5 0.0 1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER33748.1 - 4.1e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KER33748.1 - 4.7e-09 35.5 0.0 6.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KER33748.1 - 0.034 13.1 0.1 0.049 12.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KER33748.1 - 0.039 13.9 0.1 0.25 11.3 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KER33748.1 - 0.082 12.0 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KER33748.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 KER33749.1 - 3.8e-68 229.7 0.0 5.4e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33749.1 - 2.6e-52 177.7 0.0 3.8e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER33749.1 - 6.2e-06 25.7 0.0 2e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KER33749.1 - 1.9e-05 23.6 0.0 4.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KER33749.1 - 0.0067 16.4 0.0 0.022 14.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KER33749.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 KER33749.1 - 0.046 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CoA_binding PF02629.19 KER33751.1 - 1.1e-30 106.2 0.1 2.4e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KER33751.1 - 1.5e-22 80.1 0.0 3.3e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KER33751.1 - 1.3e-08 34.7 0.0 3.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KER33751.1 - 0.0018 18.7 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain NHL PF01436.21 KER33752.1 - 2.1e-30 103.2 6.9 3.6e-06 26.7 0.0 6.4 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 KER33752.1 - 2.5e-17 63.1 5.4 2.1e-08 33.7 0.1 4.2 2 2 1 4 4 4 4 6-bladed beta-propeller DUF4934 PF16288.5 KER33752.1 - 6e-06 26.1 1.0 0.003 17.4 0.2 3.5 1 1 2 4 4 4 2 Domain of unknown function (DUF4934) SGL PF08450.12 KER33752.1 - 1.1e-05 25.1 0.0 0.0094 15.6 0.0 3.8 1 1 4 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region Filamin PF00630.19 KER33752.1 - 9.7e-05 23.1 0.0 0.00052 20.8 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat Not3 PF04065.15 KER33752.1 - 0.17 11.3 2.1 0.33 10.4 1.7 1.5 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component CAP_N PF01213.19 KER33752.1 - 1.2 8.6 4.2 2.1 7.7 3.7 1.7 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SKA2 PF16740.5 KER33752.1 - 6.2 6.7 7.3 53 3.7 4.4 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 S1 PF00575.23 KER33753.1 - 0.016 15.5 0.2 0.03 14.7 0.2 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Sugar_tr PF00083.24 KER33754.1 - 6.4e-131 437.3 28.2 1.2e-92 311.2 12.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KER33754.1 - 3.8e-20 72.1 38.0 5.6e-19 68.3 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PBP_N PF17093.5 KER33754.1 - 1.1 9.5 4.0 33 4.7 0.4 2.8 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus TMEM141 PF15110.6 KER33754.1 - 1.9 9.1 5.6 3.3 8.4 0.1 3.7 4 0 0 4 4 4 0 TMEM141 protein family Sugar_tr PF00083.24 KER33755.1 - 4.1e-104 349.0 16.0 4.8e-104 348.7 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KER33755.1 - 4.4e-18 65.3 24.6 4.4e-18 65.3 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3397 PF11877.8 KER33755.1 - 0.2 11.9 14.4 0.93 9.7 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3397) ODR4-like PF14778.6 KER33757.1 - 3.8e-43 147.8 0.0 1.5e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 Olfactory receptor 4-like DHHC PF01529.20 KER33758.1 - 3.6e-33 114.5 10.0 3.6e-33 114.5 10.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ion_trans PF00520.31 KER33759.1 - 2e-32 112.4 2.1 2.6e-32 112.0 2.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER33759.1 - 2.4e-10 40.2 0.7 2.4e-10 40.2 0.7 2.5 2 0 0 2 2 2 1 Ion channel IRK PF01007.20 KER33759.1 - 0.018 14.8 5.7 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MFS_1 PF07690.16 KER33759.1 - 2.2 7.1 10.2 0.07 12.0 0.4 2.2 2 0 0 2 2 2 0 Major Facilitator Superfamily cNMP_binding PF00027.29 KER33760.1 - 8.6e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MscS_porin PF12795.7 KER33760.1 - 0.0023 17.5 1.9 0.0023 17.5 1.9 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF4349 PF14257.6 KER33760.1 - 0.013 15.0 0.1 0.034 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Baculo_PEP_C PF04513.12 KER33760.1 - 0.014 15.4 1.2 0.035 14.2 1.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgT_M PF16539.5 KER33760.1 - 0.036 14.2 0.4 0.16 12.1 0.4 2.0 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain BAR PF03114.18 KER33760.1 - 0.041 13.5 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 BAR domain Muted PF14942.6 KER33760.1 - 0.16 12.3 2.4 0.2 12.0 0.9 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein GDI PF00996.18 KER33761.1 - 1.1e-128 429.5 0.0 1.2e-128 429.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 KER33761.1 - 0.00029 20.3 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GDI PF00996.18 KER33762.1 - 2.2e-203 675.6 0.7 2.5e-203 675.4 0.7 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 KER33762.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase WD40 PF00400.32 KER33765.1 - 2.7e-15 56.5 10.3 1.4e-07 32.0 0.2 7.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33765.1 - 4.2e-12 46.2 0.5 0.037 14.3 0.0 5.4 4 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER33765.1 - 3e-05 24.0 0.0 0.00011 22.1 0.0 2.0 2 0 0 2 2 1 1 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 KER33765.1 - 8.5e-05 22.3 7.8 0.35 11.0 0.1 5.4 4 1 0 5 5 5 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KER33765.1 - 0.00016 20.9 3.7 0.095 11.7 0.1 4.2 4 2 2 6 6 6 2 Coatomer WD associated region WD40_like PF17005.5 KER33765.1 - 0.002 17.5 0.1 1.1 8.5 0.0 3.1 2 1 0 2 2 2 1 WD40-like domain ANAPC3 PF12895.7 KER33765.1 - 0.0044 17.2 0.7 5.3 7.3 0.1 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KER33765.1 - 0.023 15.2 3.6 4.2 8.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PHTB1_N PF14727.6 KER33765.1 - 0.041 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus zf-C3HC4_3 PF13920.6 KER33765.1 - 0.37 10.7 9.0 4.5 7.2 0.7 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KER33765.1 - 0.98 9.7 0.0 0.98 9.7 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER33765.1 - 2 8.8 16.6 6.6 7.1 0.1 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat SapB_1 PF05184.15 KER33766.1 - 0.022 14.8 0.1 0.086 12.9 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 PaaA_PaaC PF05138.12 KER33766.1 - 0.072 12.2 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Metallophos PF00149.28 KER33767.1 - 2.3e-19 70.7 0.9 3.4e-19 70.2 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KER33767.1 - 0.08 13.4 1.1 0.19 12.2 1.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 KER33769.1 - 8.6e-18 65.6 0.0 1.4e-17 64.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Beach PF02138.18 KER33770.1 - 2.4e-123 410.9 0.1 5.3e-123 409.8 0.0 1.7 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 KER33770.1 - 1.7e-90 303.0 1.3 3.6e-90 302.0 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 KER33770.1 - 1.9e-33 115.5 0.4 5.4e-33 114.0 0.4 1.7 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 KER33770.1 - 8e-19 67.6 0.0 1.9e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KER33770.1 - 4e-08 33.8 7.0 0.00057 20.6 0.7 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33770.1 - 0.0019 18.5 0.0 1.2 9.5 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RTT107_BRCT_5 PF16770.5 KER33771.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain LRR_8 PF13855.6 KER33772.1 - 9e-15 54.2 13.9 1.1e-09 37.9 4.5 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KER33772.1 - 1.2e-08 35.1 12.8 4.2e-05 23.8 2.5 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) I-set PF07679.16 KER33772.1 - 1.8e-08 34.3 0.1 4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 KER33772.1 - 9.5e-08 32.5 0.5 3.6e-07 30.7 0.5 2.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 KER33772.1 - 3.5e-05 23.9 0.4 0.00011 22.3 0.4 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 KER33772.1 - 0.00012 22.4 0.2 0.00038 20.7 0.2 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 KER33772.1 - 0.0012 19.1 11.9 1.5 9.7 1.2 5.4 5 0 0 5 5 4 2 Leucine Rich Repeat C1-set PF07654.15 KER33772.1 - 0.0021 18.4 0.3 0.0064 16.9 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin C1-set domain LRR_5 PF13306.6 KER33772.1 - 0.024 14.6 0.0 0.16 12.0 0.0 2.1 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) V-set PF07686.17 KER33772.1 - 0.039 14.1 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Immunoglobulin V-set domain Orthoreo_P10 PF07204.11 KER33772.1 - 0.18 11.8 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TPKR_C2 PF16920.5 KER33772.1 - 0.2 11.8 1.1 0.68 10.1 1.1 1.9 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain LRR_9 PF14580.6 KER33772.1 - 0.25 10.8 3.0 0.21 11.0 1.5 1.6 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KER33772.1 - 6.3 7.1 8.4 80 3.7 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeat DUF2769 PF10967.8 KER33774.1 - 0.053 14.2 0.0 0.068 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) NARP1 PF12569.8 KER33777.1 - 5.9e-156 520.4 5.6 1.2e-155 519.4 3.4 2.4 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KER33777.1 - 2.5e-13 49.0 18.1 1.7e-05 24.6 0.1 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER33777.1 - 4e-12 45.3 14.4 0.00014 21.8 0.1 8.2 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KER33777.1 - 5.8e-10 38.6 18.1 2.1e-05 24.2 0.2 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER33777.1 - 1.9e-09 37.5 32.1 0.054 14.3 0.0 11.8 10 2 2 12 12 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER33777.1 - 1.9e-09 37.6 12.4 0.0094 16.2 1.5 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KER33777.1 - 8.9e-09 35.7 24.0 0.00086 19.8 0.1 8.2 8 2 1 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KER33777.1 - 1e-07 32.1 10.7 0.064 13.5 0.0 6.4 3 3 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KER33777.1 - 1.4e-07 31.1 0.0 1.9e-05 24.2 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_MalT PF17874.1 KER33777.1 - 2.4e-07 30.5 7.5 0.00042 19.8 0.3 4.2 3 2 1 5 5 4 2 MalT-like TPR region TPR_17 PF13431.6 KER33777.1 - 0.00012 22.2 12.1 1.7 9.2 0.1 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KER33777.1 - 0.00013 21.8 7.8 0.0057 16.6 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KER33777.1 - 0.00025 21.4 5.3 27 5.8 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KER33777.1 - 0.00064 20.3 18.4 0.038 14.6 0.0 7.5 8 1 1 9 9 7 1 Tetratricopeptide repeat FAT PF02259.23 KER33777.1 - 0.0033 16.7 0.1 0.24 10.6 0.0 3.1 2 2 1 3 3 3 1 FAT domain TPR_6 PF13174.6 KER33777.1 - 0.0048 17.5 6.1 46 5.0 0.1 6.9 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KER33777.1 - 0.0078 16.3 10.5 0.044 13.9 0.1 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KER33777.1 - 0.05 13.7 3.7 1.5 8.9 0.2 4.9 6 1 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KER33777.1 - 0.16 10.9 1.3 2.9 6.8 0.1 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 KER33777.1 - 0.71 9.5 7.7 4.1 7.1 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KER33777.1 - 3.9 7.5 16.1 26 4.9 0.1 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Chal_sti_synt_C PF02797.15 KER33779.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain BRCA-2_OB1 PF09103.10 KER33782.1 - 4.6e-24 84.7 0.0 1.4e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KER33782.1 - 2.3e-17 63.3 0.0 5.8e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 KER33782.1 - 0.0082 15.8 4.8 0.022 14.4 0.0 3.8 5 0 0 5 5 5 1 BRCA2 repeat BRCA-2_OB3 PF09104.10 KER33782.1 - 0.021 14.5 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Gemini_AC4_5 PF04807.12 KER33782.1 - 0.071 12.8 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Tower PF09121.10 KER33782.1 - 1.5 9.1 3.7 3.5 7.9 3.7 1.6 1 0 0 1 1 1 0 Tower PORR PF11955.8 KER33784.1 - 0.00051 19.1 0.0 3.3 6.6 0.0 3.1 3 0 0 3 3 3 3 Plant organelle RNA recognition domain zf-H2C2_2 PF13465.6 KER33785.1 - 8.9e-16 57.5 20.7 7.7e-08 32.4 1.6 4.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KER33785.1 - 1.6e-14 53.4 30.9 2.7e-06 27.5 2.6 4.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KER33785.1 - 8.4e-06 25.4 25.8 0.00026 20.7 1.2 5.0 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KER33785.1 - 1.1e-05 25.9 18.7 0.0017 19.1 1.5 4.7 5 0 0 5 5 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KER33785.1 - 2.6e-05 24.4 8.2 0.054 13.8 0.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KER33785.1 - 0.007 16.8 10.6 0.17 12.3 0.3 3.6 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KER33785.1 - 0.0071 16.1 1.1 0.0071 16.1 1.1 4.0 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KER33785.1 - 0.017 15.1 0.8 0.017 15.1 0.8 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger PyrI_C PF02748.15 KER33785.1 - 0.027 14.4 0.2 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Spt46 PF17734.1 KER33785.1 - 0.084 12.7 5.3 2 8.2 1.1 2.6 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 GAGA PF09237.11 KER33785.1 - 0.33 10.8 9.3 0.64 9.9 0.3 3.1 1 1 2 3 3 3 0 GAGA factor zf-BED PF02892.15 KER33785.1 - 0.6 10.2 20.2 0.086 12.9 0.8 3.6 3 1 1 4 4 4 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KER33785.1 - 0.85 9.6 9.0 3.6 7.6 0.7 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 KER33785.1 - 2.8 8.6 9.9 8.3 7.1 0.2 3.8 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats 5_nucleotid PF05761.14 KER33786.1 - 5.2e-150 500.3 0.0 1.8e-78 264.5 0.0 2.0 2 0 0 2 2 2 2 5' nucleotidase family RVT_1 PF00078.27 KER33786.1 - 0.00027 20.5 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1664 PF07889.12 KER33786.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cadherin PF00028.17 KER33788.1 - 9e-64 212.0 14.1 1.6e-16 60.5 0.1 9.2 8 1 1 9 9 9 7 Cadherin domain Cadherin_3 PF16184.5 KER33788.1 - 5.4e-07 29.6 17.5 0.00043 20.3 0.1 5.2 6 0 0 6 6 6 3 Cadherin-like Cadherin_pro PF08758.11 KER33788.1 - 1.2e-05 25.3 0.5 8.3e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 Cadherin prodomain like Cadherin_2 PF08266.12 KER33788.1 - 2.2e-05 24.2 1.3 0.39 10.6 0.1 5.1 5 1 0 5 5 5 1 Cadherin-like Herpes_gE PF02480.16 KER33788.1 - 0.01 14.6 0.0 0.046 12.5 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Cadherin_4 PF17803.1 KER33788.1 - 0.13 12.9 12.2 0.59 10.8 0.4 4.4 4 0 0 4 4 4 0 Bacterial cadherin-like domain DUF1181 PF06680.11 KER33789.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1181) Prenylcys_lyase PF07156.14 KER33790.1 - 7.6e-74 249.0 0.0 1e-73 248.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KER33790.1 - 3.8e-17 62.7 0.1 1.3e-16 61.0 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KER33790.1 - 7.4e-16 58.1 0.5 1.5e-15 57.1 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KER33790.1 - 2.2e-05 24.2 0.6 0.00029 20.5 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KER33790.1 - 0.00014 21.2 0.1 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KER33790.1 - 0.0075 15.2 0.3 0.011 14.6 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KER33790.1 - 0.033 14.2 0.2 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KER33790.1 - 0.045 14.3 0.1 0.12 12.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KER33790.1 - 0.091 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Peptidase_M13_N PF05649.13 KER33792.1 - 5.1e-09 36.3 0.0 6.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 DUF5345 PF17280.2 KER33792.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PDZ PF00595.24 KER33794.1 - 1.9e-09 37.7 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER33794.1 - 3.3e-07 30.0 0.0 6.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KER33794.1 - 8.7e-05 22.8 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain zf-RING_2 PF13639.6 KER33795.1 - 2.3e-13 50.3 7.7 5.6e-13 49.0 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KER33795.1 - 1.3e-09 37.6 4.3 1.3e-09 37.6 4.3 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KER33795.1 - 2e-09 37.2 5.9 3.9e-09 36.2 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER33795.1 - 1.1e-08 35.2 4.3 2.9e-08 33.9 4.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KER33795.1 - 1.6e-08 34.2 6.3 3.3e-08 33.2 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KER33795.1 - 2.6e-08 33.8 0.0 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KER33795.1 - 2.8e-08 33.6 4.6 5.8e-08 32.6 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KER33795.1 - 1.5e-07 31.3 2.8 1.5e-07 31.3 2.8 2.2 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KER33795.1 - 3.5e-05 23.6 4.6 7.6e-05 22.5 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER33795.1 - 0.0004 20.4 1.4 0.00097 19.1 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KER33795.1 - 0.00087 19.1 8.1 0.021 14.7 8.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KER33795.1 - 0.05 13.8 2.3 0.16 12.2 2.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KER33795.1 - 0.091 12.6 4.9 0.17 11.7 4.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KER33795.1 - 0.18 11.5 2.0 0.37 10.5 2.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KER33795.1 - 0.28 11.1 3.5 0.74 9.8 3.5 1.8 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KER33795.1 - 1.5 9.0 5.8 3.2 7.9 5.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KER33795.1 - 5.1 7.5 6.0 1.2 9.5 2.3 1.8 2 0 0 2 2 1 0 RING-like domain Pkinase PF00069.25 KER33796.1 - 1.8e-62 211.1 0.0 2.7e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.21 KER33796.1 - 2.8e-61 206.4 0.0 4.6e-61 205.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Pkinase_Tyr PF07714.17 KER33796.1 - 3e-27 95.6 0.0 6.4e-26 91.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.24 KER33796.1 - 6.6e-16 58.4 0.2 1.4e-15 57.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 KER33796.1 - 2e-14 53.1 6.0 5.1e-08 32.6 0.3 3.8 4 0 0 4 4 4 2 L27 domain SH3_2 PF07653.17 KER33796.1 - 7e-09 35.2 0.0 1.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 KER33796.1 - 1.5e-07 31.1 0.1 3.9e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 KER33796.1 - 2.8e-05 23.6 0.5 7.1e-05 22.3 0.5 1.8 1 1 0 1 1 1 1 SH3 domain Pkinase_fungal PF17667.1 KER33796.1 - 0.00017 20.5 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SH3_9 PF14604.6 KER33796.1 - 0.00059 19.6 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 KER33796.1 - 0.0093 16.3 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain E1-E2_ATPase PF00122.20 KER33797.1 - 2.6e-45 154.2 1.8 6.7e-45 152.8 1.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KER33797.1 - 4.8e-42 143.7 2.1 4.8e-42 143.7 2.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KER33797.1 - 2.7e-21 76.8 0.0 3.2e-11 43.9 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER33797.1 - 7.3e-21 74.1 0.1 1.7e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KER33797.1 - 4.5e-18 64.7 0.0 1e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KER33797.1 - 5.5e-06 26.3 2.6 0.00064 19.5 0.3 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KER33797.1 - 0.11 12.9 0.0 0.74 10.2 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 KER33799.1 - 1.5e-31 108.8 3.2 4.4e-13 49.6 0.8 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER33799.1 - 5.9e-26 90.5 9.5 3e-08 34.1 0.7 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER33799.1 - 2e-24 85.3 21.5 1.2e-07 31.9 0.2 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER33799.1 - 2.9e-23 79.4 10.0 8.1e-05 22.7 0.4 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KER33799.1 - 7.5e-21 73.6 16.4 0.00013 22.2 0.2 6.1 6 0 0 6 6 6 5 Ankyrin repeat SOCS_box PF07525.16 KER33799.1 - 9.9e-06 25.8 0.1 2e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 SOCS box Innexin PF00876.18 KER33800.1 - 1.7e-94 317.0 19.2 3.3e-93 312.8 19.2 2.2 1 1 0 1 1 1 1 Innexin Ig_3 PF13927.6 KER33801.1 - 3e-67 223.2 47.9 1.5e-09 38.3 0.1 29.1 34 0 0 34 34 31 13 Immunoglobulin domain I-set PF07679.16 KER33801.1 - 6.2e-40 135.2 19.1 1.8e-06 27.9 0.0 19.9 20 2 1 21 21 20 7 Immunoglobulin I-set domain ig PF00047.25 KER33801.1 - 2.4e-33 114.2 40.7 0.00018 21.6 0.1 24.3 28 0 0 28 28 27 8 Immunoglobulin domain Ig_2 PF13895.6 KER33801.1 - 1.7e-31 108.4 32.5 0.00024 21.3 0.0 23.1 26 2 1 27 27 24 6 Immunoglobulin domain V-set PF07686.17 KER33801.1 - 2.5e-24 85.6 31.6 0.13 12.4 0.0 24.3 26 3 1 27 27 26 6 Immunoglobulin V-set domain Ldl_recept_a PF00057.18 KER33801.1 - 1.9e-14 53.6 41.9 5.2e-06 26.6 10.8 4.0 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Laminin_B PF00052.18 KER33801.1 - 3.2e-12 46.5 0.0 5.1e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Laminin B (Domain IV) Laminin_EGF PF00053.24 KER33801.1 - 9.5e-05 22.5 12.6 9.5e-05 22.5 12.6 6.1 3 2 2 5 5 3 3 Laminin EGF domain Adeno_E3_CR1 PF02440.15 KER33801.1 - 0.00031 20.5 0.0 4.8 7.0 0.0 4.5 4 0 0 4 4 4 1 Adenovirus E3 region protein CR1 BPL_C PF02237.17 KER33801.1 - 0.00091 19.1 22.3 1.1 9.2 0.3 9.1 9 0 0 9 9 9 1 Biotin protein ligase C terminal domain PapC_C PF13953.6 KER33801.1 - 0.0018 18.1 3.8 1.1 9.2 0.0 6.6 9 0 0 9 9 9 1 PapC C-terminal domain C2-set_2 PF08205.12 KER33801.1 - 0.0037 17.3 0.8 3.1 7.9 0.0 5.1 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain DUF5628 PF18621.1 KER33801.1 - 0.35 11.4 3.1 9.8 6.7 0.0 4.8 5 0 0 5 5 5 0 Family of unknown function (DUF5628) Glyco_hydro2_C5 PF18565.1 KER33801.1 - 5.6 6.9 11.3 28 4.6 0.0 6.7 7 0 0 7 7 7 0 Glycoside hydrolase family 2 C-terminal domain 5 EMP24_GP25L PF01105.24 KER33802.1 - 1.4e-13 51.2 3.1 1.5e-13 51.1 3.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hist_deacetyl PF00850.19 KER33803.1 - 1.3e-72 244.9 0.0 2.8e-72 243.8 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain EST1_DNA_bind PF10373.9 KER33804.1 - 3.2e-38 131.8 0.0 6.2e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain JAB PF01398.21 KER33804.1 - 2.9e-31 107.9 0.2 1.3e-30 105.8 0.2 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PIN_4 PF13638.6 KER33804.1 - 5.1e-15 55.9 0.0 1.2e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain CSN5_C PF18323.1 KER33804.1 - 3e-11 44.1 0.6 1.1e-10 42.3 0.1 2.4 2 1 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain EST1 PF10374.9 KER33804.1 - 1.5e-08 35.4 0.6 2.3e-07 31.5 0.0 2.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 Prok-JAB PF14464.6 KER33804.1 - 2.6e-05 24.0 0.0 7.1e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KER33804.1 - 0.0011 19.0 0.1 0.003 17.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) SRPRB PF09439.10 KER33805.1 - 1.3e-09 37.8 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KER33805.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KER33805.1 - 0.013 14.7 0.1 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit GTP_EFTU PF00009.27 KER33805.1 - 0.045 13.3 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4519 PF15012.6 KER33805.1 - 0.32 11.2 1.5 0.59 10.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S27 PF01599.19 KER33806.1 - 2e-26 91.9 0.9 2e-26 91.9 0.9 2.5 4 0 0 4 4 4 1 Ribosomal protein S27a ubiquitin PF00240.23 KER33806.1 - 2.9e-14 52.6 0.0 5.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KER33806.1 - 8.6e-06 25.5 0.1 1.9e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 KER33806.1 - 1 9.6 5.4 0.91 9.8 2.7 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain NAPRTase PF04095.16 KER33807.1 - 3.1e-63 213.6 0.0 6.5e-53 179.8 0.0 2.1 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 KER33807.1 - 6.3e-36 122.7 0.4 2.1e-34 117.9 0.4 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5598) FHA PF00498.26 KER33810.1 - 5.8e-14 52.2 0.3 1.6e-13 50.8 0.3 1.8 1 0 0 1 1 1 1 FHA domain CEP209_CC5 PF16574.5 KER33810.1 - 0.0014 18.8 16.9 0.0014 18.8 16.9 8.9 7 3 4 11 11 11 2 Coiled-coil region of centrosome protein CE290 PX PF00787.24 KER33812.1 - 7.4e-10 38.8 0.4 8.6e-10 38.6 0.4 1.0 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 KER33814.1 - 1.1e-17 63.6 0.2 1.9e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER33814.1 - 0.00011 22.3 0.0 0.00029 20.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KER33814.1 - 0.0077 16.2 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SUIM_assoc PF16619.5 KER33814.1 - 0.009 16.1 0.4 0.024 14.7 0.4 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DNA_ligase_A_C PF04679.15 KER33814.1 - 0.018 15.6 0.1 0.037 14.6 0.1 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region YajC PF02699.15 KER33814.1 - 0.13 12.2 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit PHM7_cyt PF14703.6 KER33814.1 - 0.34 11.1 1.6 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 KER33815.1 - 8.8e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33815.1 - 7.1e-07 28.8 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase IL11 PF07400.11 KER33817.1 - 0.11 12.2 0.2 0.3 10.7 0.2 1.7 1 0 0 1 1 1 0 Interleukin 11 DUF2120 PF09893.9 KER33817.1 - 0.19 11.9 6.5 0.06 13.4 2.2 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) ATP-synt_B PF00430.18 KER33817.1 - 3.3 7.8 6.3 2.8 8.1 1.5 2.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) START PF01852.19 KER33819.1 - 1.1e-30 106.6 0.1 1.4e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 KER33819.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) I-set PF07679.16 KER33822.1 - 5.6e-62 205.8 0.0 2.2e-17 62.9 0.0 8.9 9 0 0 9 9 9 8 Immunoglobulin I-set domain Ig_3 PF13927.6 KER33822.1 - 3.8e-48 162.0 2.5 3.3e-10 40.4 0.0 9.1 8 1 0 8 8 8 8 Immunoglobulin domain Ig_2 PF13895.6 KER33822.1 - 4.9e-23 81.3 9.7 0.00026 21.3 0.2 8.4 8 1 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 KER33822.1 - 1.6e-22 79.7 5.2 0.0032 17.6 0.1 9.8 8 1 0 8 8 8 5 Immunoglobulin V-set domain ig PF00047.25 KER33822.1 - 6.8e-18 64.6 6.9 0.032 14.4 0.3 7.5 7 0 0 7 7 7 4 Immunoglobulin domain Izumo-Ig PF16706.5 KER33822.1 - 0.001 19.1 2.3 23 5.1 0.0 4.6 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Receptor_2B4 PF11465.8 KER33822.1 - 0.029 14.6 0.1 63 3.8 0.0 4.6 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 UPF0184 PF03670.13 KER33822.1 - 0.2 12.1 0.9 0.98 9.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) AMP-binding PF00501.28 KER33824.1 - 2e-92 310.0 0.0 2.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KER33824.1 - 7.2e-20 71.7 0.0 1.7e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KER33824.1 - 6.9e-14 51.5 1.2 1.7e-13 50.2 1.2 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus MIT_C PF16565.5 KER33826.1 - 4.2e-36 124.0 0.0 7.3e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT zf-RING_2 PF13639.6 KER33827.1 - 6.1e-08 32.9 12.1 1.7e-07 31.4 12.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KER33827.1 - 5.1e-05 23.1 9.1 0.00012 21.9 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER33827.1 - 0.00034 20.6 5.9 0.0011 19.0 5.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KER33827.1 - 0.00036 20.5 13.2 0.00093 19.2 13.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger WD40 PF00400.32 KER33827.1 - 0.00096 19.9 3.1 1.8 9.6 0.2 3.3 3 0 0 3 3 2 2 WD domain, G-beta repeat zf-RING_5 PF14634.6 KER33827.1 - 0.0012 18.8 10.2 0.0025 17.7 10.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KER33827.1 - 0.013 15.8 11.6 0.047 14.0 11.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KER33827.1 - 0.017 15.0 10.6 0.051 13.4 10.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KER33827.1 - 0.028 14.2 3.5 0.095 12.5 3.5 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KER33827.1 - 0.032 14.4 7.1 0.12 12.5 7.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ANAPC4_WD40 PF12894.7 KER33827.1 - 0.07 13.4 0.0 8 6.8 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RINGv PF12906.7 KER33827.1 - 2 8.6 11.4 5.5 7.2 11.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KER33827.1 - 9.2 6.2 15.1 0.19 11.5 8.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CUTL PF16557.5 KER33828.1 - 0.09 13.0 1.0 16 5.8 0.1 2.4 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB Myosin_tail_1 PF01576.19 KER33829.1 - 5.5e-69 233.1 156.1 8.9e-69 232.4 156.1 1.4 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 KER33829.1 - 2e-16 60.5 140.5 6.9e-06 25.9 10.2 8.4 1 1 4 6 6 6 5 Intermediate filament protein Rab5-bind PF09311.11 KER33829.1 - 3.2e-06 26.8 36.2 3.2e-06 26.8 36.2 7.1 1 1 5 6 6 5 1 Rabaptin-like protein DUF3584 PF12128.8 KER33829.1 - 2.3e-05 22.2 58.1 2.3e-05 22.2 58.1 4.2 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) ATG16 PF08614.11 KER33829.1 - 5e-05 23.6 170.7 0.012 15.8 16.7 9.2 1 1 8 9 9 9 6 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KER33829.1 - 8.8e-05 21.5 143.2 0.00064 18.7 31.0 6.9 1 1 5 6 6 6 4 Spc7 kinetochore protein HMMR_N PF15905.5 KER33829.1 - 9.2e-05 22.1 20.3 9.2e-05 22.1 20.3 6.7 1 1 5 6 6 5 2 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 KER33829.1 - 0.00012 22.2 4.1 0.00012 22.2 4.1 11.4 3 2 9 12 12 12 4 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KER33829.1 - 0.00063 19.8 85.5 0.1 12.6 2.3 11.6 2 2 10 13 13 13 6 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KER33829.1 - 0.0017 18.6 4.4 0.0017 18.6 4.4 9.4 1 1 8 10 10 10 2 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KER33829.1 - 0.002 17.9 2.5 0.002 17.9 2.5 11.8 7 5 4 12 12 12 1 GIT coiled-coil Rho guanine nucleotide exchange factor HOOK PF05622.12 KER33829.1 - 0.0022 16.2 21.0 0.0022 16.2 21.0 5.6 1 1 3 5 5 4 3 HOOK protein JIP_LZII PF16471.5 KER33829.1 - 0.0025 17.9 8.0 0.0025 17.9 8.0 14.2 4 3 12 17 17 16 2 JNK-interacting protein leucine zipper II KASH_CCD PF14662.6 KER33829.1 - 0.003 17.4 21.1 0.003 17.4 21.1 8.8 2 2 6 8 8 7 4 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KER33829.1 - 0.0042 16.9 0.3 0.0042 16.9 0.3 8.5 9 0 0 9 9 8 3 Shugoshin N-terminal coiled-coil region HR1 PF02185.16 KER33829.1 - 0.0045 17.1 9.9 0.0045 17.1 9.9 11.7 4 3 6 10 10 7 1 Hr1 repeat TolA_bind_tri PF16331.5 KER33829.1 - 0.0056 16.7 2.0 0.0056 16.7 2.0 14.4 6 4 8 14 14 14 5 TolA binding protein trimerisation ZapB PF06005.12 KER33829.1 - 0.015 15.7 5.8 0.015 15.7 5.8 14.4 5 4 7 12 12 7 0 Cell division protein ZapB HALZ PF02183.18 KER33829.1 - 0.018 15.3 5.8 0.018 15.3 5.8 13.8 16 4 2 18 18 13 0 Homeobox associated leucine zipper TSC22 PF01166.18 KER33829.1 - 0.083 13.2 0.3 0.083 13.2 0.3 10.7 6 3 5 12 12 12 0 TSC-22/dip/bun family NumbF PF06311.12 KER33829.1 - 0.092 13.3 0.3 0.092 13.3 0.3 6.3 5 2 0 6 6 5 0 NUMB domain YqjK PF13997.6 KER33829.1 - 2.3 8.5 8.8 8.8 6.6 0.5 3.8 3 1 1 4 4 3 0 YqjK-like protein Baculo_PEP_C PF04513.12 KER33829.1 - 2.6 8.1 74.1 4.9 7.2 2.7 8.8 1 1 7 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KER33829.1 - 2.7 7.2 122.7 0.91 8.8 22.6 7.1 1 1 5 6 6 5 0 Domain of unknown function (DUF4407) Cir_Bir_Yir PF06022.11 KER33829.1 - 4.5 6.7 13.3 0.6 9.5 0.0 3.4 3 1 0 3 3 3 0 Plasmodium variant antigen protein Cir/Yir/Bir CENP-F_leu_zip PF10473.9 KER33829.1 - 7.8 6.5 154.6 0.66 10.0 21.7 10.0 2 2 8 10 10 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KER33829.1 - 8.4 6.6 152.1 0.016 15.4 16.0 9.3 1 1 7 9 9 9 0 JNK_SAPK-associated protein-1 GRDP-like PF07173.12 KER33830.1 - 4e-25 89.1 8.5 6.3e-21 75.5 0.3 4.0 3 1 1 4 4 4 3 Glycine-rich domain-containing protein-like zf-RING_2 PF13639.6 KER33832.1 - 8.7e-09 35.6 11.6 2.4e-08 34.2 11.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KER33832.1 - 1.2e-06 28.7 8.1 3.6e-06 27.2 8.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KER33832.1 - 1.5e-06 28.0 5.6 1.5e-06 28.0 5.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER33832.1 - 3e-05 23.8 9.6 6.6e-05 22.7 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER33832.1 - 0.00012 21.8 7.6 0.0003 20.6 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KER33832.1 - 0.00016 21.6 7.2 0.00039 20.3 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KER33832.1 - 0.00023 20.8 7.7 0.00029 20.5 4.5 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KER33832.1 - 0.0014 18.6 8.7 0.0028 17.6 5.7 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER33832.1 - 0.0015 18.4 8.9 0.0033 17.3 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KER33832.1 - 0.084 12.9 4.6 0.19 11.8 4.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KER33832.1 - 0.15 11.7 7.9 0.38 10.4 7.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type G2BR PF18442.1 KER33832.1 - 0.16 11.6 2.5 0.28 10.8 2.5 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) zf-P11 PF03854.14 KER33832.1 - 0.22 11.2 11.0 0.094 12.4 6.5 2.7 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 KER33832.1 - 0.57 10.4 7.9 1.7 8.9 7.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SapB_1 PF05184.15 KER33833.1 - 0.00038 20.4 3.7 0.0016 18.4 0.1 3.3 3 0 0 3 3 3 1 Saposin-like type B, region 1 DUF575 PF04746.12 KER33834.1 - 0.064 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) DEAD PF00270.29 KER33835.1 - 1.6e-49 168.0 0.0 2.6e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KER33835.1 - 8.2e-32 109.9 0.0 1.7e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1 PF07690.16 KER33836.1 - 1.2e-13 50.8 26.5 9.6e-07 28.0 4.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UQ_con PF00179.26 KER33837.1 - 1.6e-19 70.0 0.0 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CTP_synth_N PF06418.14 KER33838.1 - 7.5e-122 405.7 0.1 1e-121 405.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KER33838.1 - 1.9e-40 138.7 0.0 2.3e-32 112.3 0.0 2.5 2 1 0 2 2 2 2 Glutamine amidotransferase class-I Radial_spoke PF04712.12 KER33839.1 - 4.1e-138 461.4 5.3 1.2e-125 420.3 1.8 3.0 1 1 2 3 3 3 2 Radial spokehead-like protein YIF1 PF03878.15 KER33840.1 - 3.6e-80 268.9 4.0 4.8e-80 268.5 4.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KER33840.1 - 1.3e-07 31.5 10.4 2.9e-07 30.4 9.1 1.9 2 0 0 2 2 2 1 Yip1 domain DUF2070 PF09843.9 KER33840.1 - 8 4.6 7.3 9.8 4.3 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) C1q PF00386.21 KER33841.1 - 9.5e-24 84.0 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 KER33841.1 - 6.4e-05 22.9 0.0 0.00016 21.6 0.0 1.6 1 1 1 2 2 2 1 BclA C-terminal domain Collagen PF01391.18 KER33841.1 - 0.00068 19.4 3.0 0.0012 18.6 3.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-C4 PF00105.18 KER33842.1 - 6.1e-23 81.1 16.5 1.1e-22 80.3 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 KER33842.1 - 0.0025 17.9 8.3 0.0082 16.2 6.9 2.1 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type c-SKI_SMAD_bind PF08782.10 KER33842.1 - 0.28 11.4 4.4 2.3 8.5 2.5 2.5 2 0 0 2 2 2 0 c-SKI Smad4 binding domain Hormone_recep PF00104.30 KER33843.1 - 0.048 13.2 0.1 0.072 12.7 0.1 1.5 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Kin17_mid PF10357.9 KER33844.1 - 5.5e-46 155.6 1.7 5.8e-46 155.5 0.4 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 KER33844.1 - 3.6e-13 49.4 0.8 7.6e-13 48.4 0.8 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 KER33844.1 - 0.0058 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 KOW motif Toxin_23 PF08093.11 KER33844.1 - 0.063 13.4 0.6 0.23 11.6 0.6 2.0 1 0 0 1 1 1 0 Magi 5 toxic peptide family MCPVI PF02993.14 KER33844.1 - 2.3 8.0 4.3 3.6 7.3 1.0 2.1 1 1 1 2 2 2 0 Minor capsid protein VI PHD PF00628.29 KER33845.1 - 5.6e-12 45.4 4.6 1.1e-11 44.4 4.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KER33845.1 - 0.00018 21.0 4.7 0.00021 20.8 1.8 2.2 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.20 KER33845.1 - 0.14 11.9 2.7 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 KER33845.1 - 3.8 7.9 8.2 8.6 6.8 8.2 1.6 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 KER33845.1 - 5 7.3 7.3 1.3 9.1 2.9 2.3 2 0 0 2 2 2 0 PHD-finger Bromo_TP PF07524.13 KER33848.1 - 1.6e-06 28.0 0.1 3.4e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KER33848.1 - 1.7e-06 28.2 0.0 2.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone-fold protein ThiF PF00899.21 KER33850.1 - 2.7e-16 59.7 0.0 1.6e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 ThiF family HAT PF02184.16 KER33851.1 - 3.1e-29 100.6 65.9 1.3e-06 28.2 0.2 13.8 12 2 0 12 12 12 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KER33851.1 - 1.4e-23 81.6 21.5 0.01 16.6 0.1 11.1 6 3 5 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 KER33851.1 - 5.9e-19 68.3 0.9 0.0014 19.1 0.0 7.7 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KER33851.1 - 5e-11 43.1 7.2 0.55 10.9 0.0 7.4 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KER33851.1 - 1.6e-09 37.4 0.8 0.00061 20.0 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Suf PF05843.14 KER33851.1 - 2.5e-08 34.3 44.4 2e-05 24.7 7.4 6.3 2 1 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KER33851.1 - 1.2e-05 25.0 21.3 4 7.8 0.1 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KER33851.1 - 2.2e-05 24.7 8.8 1.1 9.6 0.0 6.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KER33851.1 - 0.00018 21.5 6.6 14 6.2 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KER33851.1 - 0.0019 18.2 29.6 0.091 12.7 3.9 7.1 7 2 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 KER33851.1 - 0.0024 18.4 19.3 4.9 8.0 0.2 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat BSD PF03909.17 KER33851.1 - 0.029 14.4 2.2 1.4 9.0 0.2 2.8 2 0 0 2 2 2 0 BSD domain TPR_7 PF13176.6 KER33851.1 - 0.041 13.9 3.9 18 5.6 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KER33851.1 - 0.11 12.6 8.8 4.7 7.4 0.1 5.3 5 1 0 6 6 6 0 Tetratricopeptide repeat Apt1 PF10351.9 KER33851.1 - 2.7 6.8 11.6 0.091 11.6 5.5 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain ECH_1 PF00378.20 KER33854.1 - 1.8e-51 174.9 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KER33854.1 - 2.9e-21 76.3 0.0 4.9e-20 72.3 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Phosphodiest PF01663.22 KER33855.1 - 6.7e-13 49.0 3.0 8.2e-12 45.4 3.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KER33855.1 - 3.3e-05 23.4 0.1 4.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KER33855.1 - 0.00018 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Ets PF00178.22 KER33856.1 - 8.2e-32 109.5 0.5 1.9e-31 108.4 0.5 1.6 1 0 0 1 1 1 1 Ets-domain VWA_N PF08399.11 KER33857.1 - 1.1e-24 87.2 0.5 3.7e-24 85.6 0.1 2.0 2 0 0 2 2 2 1 VWA N-terminal VWA_3 PF13768.6 KER33857.1 - 1.9e-10 40.9 0.0 8.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KER33857.1 - 2e-08 34.8 0.2 7.8e-08 32.9 0.3 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KER33857.1 - 1.1e-07 32.2 0.1 2e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 KER33857.1 - 1.3e-07 31.7 0.1 4.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Cache domain CobT_C PF11775.8 KER33857.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain zf-CXXC PF02008.20 KER33860.1 - 2.7e-15 56.1 19.2 2.7e-15 56.1 19.2 2.3 3 0 0 3 3 3 1 CXXC zinc finger domain PHD PF00628.29 KER33860.1 - 7.4e-11 41.8 9.7 7.4e-11 41.8 9.7 3.2 3 0 0 3 3 3 1 PHD-finger Ras PF00071.22 KER33862.1 - 9.3e-57 191.2 0.1 1.1e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER33862.1 - 5.6e-22 78.2 0.0 8e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER33862.1 - 2.5e-08 33.6 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER33862.1 - 2.1e-05 24.5 0.0 0.14 12.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KER33862.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KER33862.1 - 0.0087 15.6 0.1 0.023 14.2 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AlkA_N PF06029.11 KER33862.1 - 0.037 14.3 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 AlkA N-terminal domain EGF PF00008.27 KER33863.1 - 0.0016 18.7 42.0 0.026 14.8 5.5 5.4 5 0 0 5 5 5 4 EGF-like domain YiaAB PF05360.14 KER33863.1 - 0.78 10.0 2.7 0.43 10.8 0.3 1.8 2 0 0 2 2 2 0 yiaA/B two helix domain HLH PF00010.26 KER33864.1 - 2.7e-09 36.8 1.9 6.2e-09 35.7 1.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 KER33864.1 - 0.2 11.5 0.6 0.39 10.5 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Pkinase_Tyr PF07714.17 KER33865.1 - 1.1e-26 93.7 0.0 2.4e-23 82.7 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KER33865.1 - 3.1e-25 89.0 0.0 3.2e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain TGF_beta_GS PF08515.12 KER33865.1 - 8e-10 38.0 3.4 1.9e-09 36.9 3.4 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.23 KER33865.1 - 0.00015 22.8 8.1 0.00015 22.8 8.1 2.7 2 0 0 2 2 2 1 Activin types I and II receptor domain Pkinase_fungal PF17667.1 KER33865.1 - 0.00098 18.0 0.1 0.0022 16.8 0.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase ODV-E18 PF10717.9 KER33865.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DAO PF01266.24 KER33866.1 - 6.2e-16 58.9 0.0 6.9e-15 55.5 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.6 KER33866.1 - 0.0091 17.0 0.0 0.017 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KER33866.1 - 0.052 13.5 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Astacin PF01400.24 KER33867.1 - 1.8e-36 125.5 0.0 4e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 KER33867.1 - 3.1e-13 50.0 84.4 2.3e-05 24.8 5.4 7.7 7 0 0 7 7 7 6 ShK domain-like Peptidase_M10 PF00413.24 KER33867.1 - 1.6 8.6 4.6 25 4.7 1.7 2.4 1 1 1 2 2 2 0 Matrixin EF-hand_1 PF00036.32 KER33868.1 - 1.7e-14 52.2 0.1 6.4e-06 25.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KER33868.1 - 5.4e-14 50.8 0.5 2.7e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KER33868.1 - 1.3e-10 41.5 1.0 0.00096 19.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KER33868.1 - 1.2e-08 34.0 0.2 0.0012 18.3 0.0 2.9 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KER33868.1 - 2e-08 34.0 0.7 0.07 13.0 0.0 4.4 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 KER33868.1 - 0.00027 21.2 0.0 1.5 9.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain FlhC PF05280.11 KER33868.1 - 0.0007 19.4 0.0 0.091 12.5 0.0 2.5 3 0 0 3 3 3 1 Flagellar transcriptional activator (FlhC) SBDS PF01172.18 KER33868.1 - 0.0062 16.6 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TFIID_NTD2 PF04494.15 KER33868.1 - 0.0087 16.3 0.2 1.1 9.5 0.0 2.2 1 1 1 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain Ssu72 PF04722.13 KER33868.1 - 0.011 15.3 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Ssu72-like protein UPF0154 PF03672.13 KER33868.1 - 0.12 12.5 0.0 8 6.6 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Acyl-CoA_ox_N PF14749.6 KER33868.1 - 0.13 12.8 0.0 0.51 10.9 0.0 1.8 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal RNA_pol_Rpb4 PF03874.16 KER33868.1 - 0.15 12.4 0.0 21 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb4 Rad51 PF08423.11 KER33869.1 - 6.5e-18 64.9 0.0 1.6e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KER33869.1 - 4.8e-07 29.4 0.0 7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KER33869.1 - 5.5e-06 26.1 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KER33869.1 - 3.4e-05 23.3 0.1 5.7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KER33869.1 - 0.042 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PAXNEB PF05625.11 KER33869.1 - 0.066 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein Pribosyltran_N PF13793.6 KER33870.1 - 1.5e-48 163.5 0.7 2.4e-44 150.0 0.0 3.0 3 0 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KER33870.1 - 9.5e-40 136.6 3.1 1.8e-34 119.4 0.5 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KER33870.1 - 9.2e-15 54.5 0.9 1.1e-13 51.0 0.4 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KER33870.1 - 0.001 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pox_LP_H2 PF03356.15 KER33870.1 - 0.045 13.6 0.1 2.8 7.8 0.0 2.5 1 1 1 2 2 2 0 Viral late protein H2 Lar_N PF09861.9 KER33870.1 - 0.17 11.0 0.4 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Lactate racemase N-terminal domain PRK PF00485.18 KER33871.1 - 4.5e-36 124.4 0.0 5.3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KER33871.1 - 0.0038 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KER33871.1 - 0.0082 16.7 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Usp PF00582.26 KER33872.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family G-alpha PF00503.20 KER33874.1 - 4.7e-85 285.9 6.3 2.1e-82 277.1 3.4 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KER33874.1 - 2.7e-16 59.5 1.8 2.1e-12 46.9 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER33874.1 - 9.1e-05 21.9 1.7 0.0068 15.8 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KER33874.1 - 0.00053 20.2 1.5 0.42 10.8 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KER33874.1 - 0.024 14.2 0.4 0.062 12.8 0.1 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KER33874.1 - 0.043 13.2 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF4476 PF14771.6 KER33874.1 - 0.069 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) ATP_bind_1 PF03029.17 KER33874.1 - 0.14 11.9 0.3 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 KER33874.1 - 0.15 11.2 0.2 0.77 8.9 0.1 2.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KER33874.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.7 KER33875.1 - 3.9e-35 120.3 3.9 2.5e-15 56.8 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER33875.1 - 2.2e-29 101.1 7.2 1.1e-09 38.4 1.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KER33875.1 - 5.7e-26 90.6 3.2 1.7e-09 38.0 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER33875.1 - 3.9e-24 82.1 5.5 0.00023 21.3 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KER33875.1 - 4.1e-24 83.9 8.3 0.00036 20.8 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Spore_GerAC PF05504.11 KER33875.1 - 1.3 9.2 3.6 0.55 10.4 0.2 2.1 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal JAKMIP_CC3 PF16034.5 KER33876.1 - 7e-07 29.4 13.1 7e-07 29.4 13.1 4.7 3 1 1 4 4 4 2 JAKMIP CC3 domain DUF1706 PF08020.11 KER33876.1 - 0.072 13.0 0.1 0.072 13.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1706) Ribonuclease_3 PF00636.26 KER33876.1 - 0.11 13.1 0.6 0.36 11.5 0.6 1.9 1 0 0 1 1 1 0 Ribonuclease III domain Baculo_PEP_C PF04513.12 KER33876.1 - 0.25 11.4 16.8 1.3 9.0 1.2 4.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PKcGMP_CC PF16808.5 KER33876.1 - 0.29 11.0 16.4 19 5.2 0.1 5.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DMSP_lyase PF16867.5 KER33876.1 - 3.4 7.3 5.2 1.2 8.8 0.7 2.7 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Pkinase PF00069.25 KER33877.1 - 2.1e-35 122.4 0.0 3.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33877.1 - 5.3e-29 101.3 0.0 1.1e-28 100.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 KER33877.1 - 2.1e-12 46.3 0.2 6.3e-12 44.8 0.2 1.9 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 KER33877.1 - 0.0049 15.7 0.1 0.0098 14.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RVT_1 PF00078.27 KER33878.1 - 2.3e-12 46.9 0.0 4.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSA PF07529.13 KER33878.1 - 7.5e-07 29.4 0.1 1.9e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 HSA SNF2_N PF00176.23 KER33878.1 - 4.7e-06 25.6 0.1 2.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2845 PF11006.8 KER33879.1 - 0.0092 16.1 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) UPF0016 PF01169.19 KER33880.1 - 1.5e-28 98.9 17.7 3.4e-23 81.7 5.7 2.5 2 1 0 2 2 2 2 Uncharacterized protein family UPF0016 FSH1 PF03959.13 KER33882.1 - 7.3e-47 159.8 0.1 2.4e-46 158.1 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KER33882.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KER33882.1 - 0.048 12.9 0.0 0.18 11.1 0.0 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF829 PF05705.14 KER33882.1 - 0.067 13.1 0.0 0.26 11.1 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF829) EnY2 PF10163.9 KER33883.1 - 2.4e-21 75.9 0.0 3.1e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 PRK PF00485.18 KER33884.1 - 0.00048 19.9 0.0 0.0007 19.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Asparaginase PF00710.20 KER33886.1 - 6.1e-59 198.8 0.0 1e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KER33886.1 - 4.5e-25 88.1 0.1 9.6e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KER33886.1 - 5.1e-16 59.0 0.2 3.1e-08 34.1 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER33886.1 - 2.5e-14 53.4 0.5 2.6e-07 31.1 0.1 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KER33886.1 - 5.8e-14 52.0 0.0 2e-08 34.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER33886.1 - 1.8e-10 40.1 0.7 0.0032 17.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KER33886.1 - 3.6e-05 24.0 1.2 0.85 10.2 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Prenyltrans PF00432.21 KER33887.1 - 2.5e-64 212.7 6.0 4.4e-14 51.9 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KER33887.1 - 2.3e-05 23.7 0.0 0.029 13.5 0.0 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KER33887.1 - 2.8e-05 23.4 0.0 0.0026 16.9 0.0 2.7 1 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Aldose_epim PF01263.20 KER33888.1 - 2.5e-53 181.3 0.0 3.2e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MHC_I_3 PF16497.5 KER33889.1 - 0.014 14.9 0.4 0.063 12.8 0.0 2.2 2 0 0 2 2 2 0 MHC-I family domain SNF2_N PF00176.23 KER33892.1 - 1.8e-55 188.1 0.1 3.7e-55 187.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER33892.1 - 1.3e-12 48.0 0.6 2.6e-11 43.9 0.6 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ADD_ATRX PF17981.1 KER33892.1 - 7.5e-09 35.3 0.3 2.1e-08 33.9 0.3 1.8 1 0 0 1 1 1 1 Cysteine Rich ADD domain ResIII PF04851.15 KER33892.1 - 9.1e-07 29.0 0.0 4.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2340 PF10209.9 KER33892.1 - 0.017 15.6 0.1 0.082 13.4 0.1 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) PHD PF00628.29 KER33892.1 - 0.19 11.7 12.9 0.084 12.8 9.8 2.1 2 0 0 2 2 2 0 PHD-finger IBN_N PF03810.19 KER33896.1 - 4.8e-07 29.6 0.0 2.2e-06 27.5 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KER33896.1 - 0.0013 19.2 5.3 3 8.4 0.2 4.7 3 0 0 3 3 3 2 HEAT-like repeat Xpo1 PF08389.12 KER33896.1 - 0.0075 16.3 4.3 0.051 13.6 0.0 4.0 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.6 KER33896.1 - 0.03 14.7 2.9 1.8 9.0 0.1 4.5 5 1 1 6 6 6 0 HEAT repeats DUF2457 PF10446.9 KER33896.1 - 0.072 12.2 7.6 0.1 11.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDT PF02791.17 KER33896.1 - 0.097 13.0 0.8 1.1 9.6 1.1 2.8 2 0 0 2 2 2 0 DDT domain Miga PF10265.9 KER33899.1 - 2.8e-81 274.1 0.7 3.9e-80 270.4 0.3 2.2 2 0 0 2 2 2 2 Mitoguardin Es2 PF09751.9 KER33900.1 - 1.7e-38 133.5 4.5 5.6e-24 85.7 0.2 3.4 3 0 0 3 3 3 3 Nuclear protein Es2 Ion_trans PF00520.31 KER33901.1 - 2.7e-45 154.5 10.3 3.5e-45 154.2 10.3 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER33901.1 - 1.4e-27 95.8 0.1 2.6e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER33901.1 - 6.3e-13 48.5 5.7 6.3e-13 48.5 5.7 1.9 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 KER33901.1 - 0.049 12.3 2.7 0.078 11.6 2.7 1.4 1 0 0 1 1 1 0 Polycystin cation channel BTB_3 PF16017.5 KER33901.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Slx4 PF09494.10 KER33902.1 - 1.4e-07 31.3 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease BTB PF00651.31 KER33902.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain TFIIF_alpha PF05793.12 KER33902.1 - 1.1 7.7 3.0 2.1 6.8 3.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Snf7 PF03357.21 KER33904.1 - 2.8e-34 118.2 19.7 5.8e-34 117.2 18.0 1.9 2 0 0 2 2 2 1 Snf7 rve PF00665.26 KER33904.1 - 0.0014 18.9 0.1 0.0053 17.0 0.0 2.0 3 0 0 3 3 3 1 Integrase core domain DUF5082 PF16888.5 KER33904.1 - 0.022 15.0 3.4 0.043 14.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GAS PF13851.6 KER33904.1 - 0.025 13.9 11.1 0.045 13.1 11.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SAPIS-gp6 PF16722.5 KER33904.1 - 0.06 13.8 3.1 0.18 12.2 3.1 1.7 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus T2SSM_b PF10741.9 KER33904.1 - 0.061 13.1 1.6 0.095 12.5 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Ist1 PF03398.14 KER33904.1 - 0.066 13.1 6.4 0.1 12.5 6.4 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway GTP-bdg_M PF16360.5 KER33904.1 - 0.099 13.2 2.1 3.8 8.2 1.9 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Spore_III_AF PF09581.10 KER33904.1 - 0.24 11.4 4.2 0.42 10.6 4.3 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TetR_C_34 PF17929.1 KER33904.1 - 0.32 11.1 1.8 0.36 10.9 0.2 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Tropomyosin_1 PF12718.7 KER33904.1 - 1.6 8.9 11.4 2.7 8.1 11.4 1.3 1 0 0 1 1 1 0 Tropomyosin like Exonuc_VII_L PF02601.15 KER33904.1 - 2 7.9 7.4 2.8 7.4 7.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 KER33904.1 - 3 7.8 13.7 0.17 11.8 4.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF1359 PF07097.11 KER33904.1 - 9.8 6.5 8.7 1 9.7 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) IQ_SEC7_PH PF16453.5 KER33905.1 - 1.5e-54 183.7 0.1 2.8e-54 182.8 0.1 1.5 1 0 0 1 1 1 1 PH domain Sec7 PF01369.20 KER33905.1 - 6.5e-54 182.4 0.0 1e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_5 PF15405.6 KER33905.1 - 0.012 15.7 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain T2SSM PF04612.12 KER33905.1 - 0.061 13.4 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M BRCT PF00533.26 KER33907.1 - 5e-44 148.6 0.0 8.4e-11 42.1 0.0 7.6 7 1 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KER33907.1 - 7e-44 147.6 7.2 1.4e-17 63.3 0.4 8.3 9 1 0 9 9 9 5 twin BRCT domain BRCT_2 PF16589.5 KER33907.1 - 2.9e-28 98.1 0.0 3e-05 24.3 0.0 7.7 8 0 0 8 8 8 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KER33907.1 - 2.9e-12 46.3 0.0 8.5e-07 28.8 0.0 4.7 5 0 0 5 5 5 3 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KER33907.1 - 1.7e-09 37.9 1.2 2.2 8.6 0.0 7.4 7 1 0 7 7 7 3 DNA ligase 3 BRCT domain Ubie_methyltran PF01209.18 KER33908.1 - 6.5e-82 274.4 0.0 8.7e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KER33908.1 - 2.2e-14 53.9 0.0 1.3e-13 51.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KER33908.1 - 3.8e-14 53.1 0.0 9.6e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KER33908.1 - 2.2e-13 50.2 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KER33908.1 - 5.5e-06 27.1 0.0 1.3e-05 25.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain BacA PF02673.18 KER33908.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA DNase_NucA_NucB PF14040.6 KER33909.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB 14-3-3 PF00244.20 KER33910.1 - 4.1e-86 288.1 2.4 5.4e-86 287.7 2.4 1.1 1 0 0 1 1 1 1 14-3-3 protein Limkain-b1 PF11608.8 KER33911.1 - 0.019 15.0 0.1 0.069 13.2 0.1 1.9 1 0 0 1 1 1 0 Limkain b1 HTH_46 PF15977.5 KER33911.1 - 0.026 14.5 0.2 0.07 13.2 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Arm PF00514.23 KER33911.1 - 0.12 12.5 3.0 5 7.3 0.2 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MIR PF02815.19 KER33912.1 - 2.5e-12 47.0 0.1 4.9e-08 33.0 0.0 2.7 1 1 2 3 3 3 3 MIR domain zf-CCCH PF00642.24 KER33913.1 - 1.2e-13 50.6 16.6 2.8e-07 30.3 6.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KER33913.1 - 0.00014 21.8 16.8 0.0025 17.8 5.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KER33913.1 - 0.00047 20.8 9.6 0.0073 17.0 1.0 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KER33913.1 - 0.00081 19.1 16.5 0.046 13.5 4.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KER33913.1 - 0.022 15.3 18.8 0.13 12.8 5.0 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lustrin_cystein PF14625.6 KER33913.1 - 0.039 14.3 7.1 2 8.9 0.9 2.5 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain ATX_III PF08098.11 KER33913.1 - 0.12 12.4 7.4 0.28 11.2 0.5 2.5 2 0 0 2 2 2 0 Anemonia sulcata toxin III family Nab2p_Zf1 PF18260.1 KER33913.1 - 0.13 12.2 9.0 1.5 8.8 3.6 2.5 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Glyoxalase PF00903.25 KER33914.1 - 0.0003 21.0 0.0 0.0055 16.9 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 KER33914.1 - 0.067 13.3 0.0 0.57 10.3 0.0 2.3 3 0 0 3 3 3 0 CppA N-terminal WD40 PF00400.32 KER33915.1 - 0.0031 18.3 0.2 0.93 10.5 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 KER33919.1 - 2.8e-12 46.8 10.0 2.8e-12 46.8 10.0 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KER33919.1 - 1.5e-07 31.1 12.4 1.5e-07 31.1 12.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KER33919.1 - 5e-07 29.4 8.2 5e-07 29.4 8.2 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KER33919.1 - 7.2e-07 29.0 5.9 7.2e-07 29.0 5.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KER33919.1 - 2.5e-05 24.5 11.6 2.5e-05 24.5 11.6 2.5 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KER33919.1 - 9.5e-05 22.3 5.4 9.5e-05 22.3 5.4 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 KER33919.1 - 0.00034 20.8 0.7 0.00034 20.8 0.7 3.6 4 1 0 4 4 4 1 zinc-ribbon Prok-RING_4 PF14447.6 KER33919.1 - 0.00042 20.1 8.2 0.00042 20.1 8.2 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KER33919.1 - 0.001 18.9 10.5 0.001 18.9 10.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KER33919.1 - 0.001 18.7 7.9 0.001 18.7 7.9 2.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KER33919.1 - 0.0031 17.4 8.9 0.0031 17.4 8.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_16 PF17034.5 KER33919.1 - 0.0045 17.2 1.1 0.0045 17.2 1.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon like family zf-HC5HC2H_2 PF13832.6 KER33919.1 - 0.0057 16.8 3.2 0.0057 16.8 3.2 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 KER33919.1 - 0.0069 16.4 6.5 0.0069 16.4 6.5 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KER33919.1 - 0.022 15.0 4.7 0.022 15.0 4.7 3.2 2 2 1 3 3 3 0 PHD-like zinc-binding domain Zn-ribbon_8 PF09723.10 KER33919.1 - 0.37 11.0 0.2 0.37 11.0 0.2 2.8 3 0 0 3 3 2 0 Zinc ribbon domain zf-C3H2C3 PF17122.5 KER33919.1 - 3 7.9 12.3 0.17 12.0 5.9 2.3 2 1 0 2 2 1 0 Zinc-finger FANCL_C PF11793.8 KER33919.1 - 3.8 7.8 12.6 12 6.1 8.7 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain Vps39_2 PF10367.9 KER33919.1 - 4.2 7.9 7.0 10 6.6 3.1 2.7 3 1 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.11 KER33919.1 - 4.4 7.7 14.9 0.12 12.6 8.1 2.0 2 0 0 2 2 1 0 RING-like domain Med4 PF10018.9 KER33920.1 - 4.4e-24 85.3 0.2 4.4e-24 85.3 0.2 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 LapD_MoxY_N PF16448.5 KER33920.1 - 0.15 11.9 1.8 0.36 10.7 1.8 1.6 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain IF-2B PF01008.17 KER33920.1 - 0.38 9.9 4.0 0.53 9.4 4.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family GRIP PF01465.20 KER33921.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 GRIP domain BRE1 PF08647.11 KER33921.1 - 0.58 10.3 57.4 0.16 12.1 6.5 6.7 6 1 1 7 7 7 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 KER33921.1 - 0.65 10.4 67.5 12 6.3 13.8 6.6 4 1 3 7 7 7 0 Fez1 FliD_N PF02465.18 KER33921.1 - 4.9 7.9 20.8 4.1 8.2 1.2 6.4 5 2 1 6 6 6 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 KER33921.1 - 7.7 6.7 50.1 1.1 9.4 9.3 7.5 5 2 2 8 8 8 0 Fibrinogen alpha/beta chain family ZZ PF00569.17 KER33922.1 - 0.00013 21.7 4.8 0.00024 20.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 KER33922.1 - 0.015 15.5 1.2 0.036 14.2 1.2 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF2719 PF10891.8 KER33922.1 - 0.033 14.1 2.4 1.6 8.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2719) WcbI PF18588.1 KER33922.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI DUF2225 PF09986.9 KER33922.1 - 1.5 8.5 6.5 4.6 6.9 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1690 PF07956.11 KER33923.1 - 6.6e-05 23.3 0.1 8.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Pet191_N PF10203.9 KER33923.1 - 0.014 15.7 1.1 0.02 15.2 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DENN PF02141.21 KER33924.1 - 7.2e-26 91.3 2.3 7.2e-26 91.3 2.3 2.5 2 1 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 KER33924.1 - 0.0057 16.6 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 dDENN domain Avl9 PF09794.9 KER33924.1 - 0.23 10.1 0.3 0.36 9.5 0.3 1.2 1 0 0 1 1 1 0 Transport protein Avl9 La PF05383.17 KER33925.1 - 9.9e-22 76.8 0.0 2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 La domain PAM2 PF07145.15 KER33925.1 - 2.1e-05 23.9 1.5 3.2e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 Ataxin-2 C-terminal region DUF5094 PF17015.5 KER33929.1 - 0.017 15.2 0.6 0.027 14.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) RNA_pol_Rpb5_N PF03871.14 KER33929.1 - 0.048 14.2 0.1 0.15 12.7 0.1 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain HALZ PF02183.18 KER33929.1 - 0.1 12.9 4.9 0.12 12.7 1.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper GIT_CC PF16559.5 KER33929.1 - 0.26 11.2 2.5 0.73 9.7 0.4 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 KER33929.1 - 1.6 8.9 8.8 9 6.5 1.4 3.0 2 1 1 3 3 3 0 bZIP transcription factor PRKG1_interact PF15898.5 KER33929.1 - 2.9 8.9 9.4 5 8.1 0.4 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 KER33929.1 - 5.1 7.6 9.5 32 5.1 0.2 3.0 2 1 0 2 2 2 0 Cell division protein ZapB TPR_2 PF07719.17 KER33930.1 - 0.032 14.3 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KER33930.1 - 0.17 12.2 2.5 2 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KER33930.1 - 0.21 11.8 5.2 1.5 9.1 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 CK2S PF15011.6 KER33932.1 - 0.13 12.2 0.1 24 4.8 0.0 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate Zn_ribbon_2 PF12674.7 KER33932.1 - 2 9.2 4.5 47 4.7 0.1 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain HlyIII PF03006.20 KER33933.1 - 1.7e-65 220.9 22.0 2.1e-65 220.6 22.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Acetyltransf_1 PF00583.25 KER33935.1 - 1.5e-17 63.9 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KER33935.1 - 1.5e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KER33935.1 - 9.6e-12 44.7 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KER33935.1 - 2.4e-10 40.4 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KER33935.1 - 2.2e-06 27.4 0.0 5.6e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KER33935.1 - 0.00014 22.5 0.0 0.00019 22.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KER33935.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KER33935.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ion_trans PF00520.31 KER33936.1 - 3.9e-17 62.3 18.6 5.6e-17 61.8 18.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KER33936.1 - 1.3e-10 41.1 8.0 1.3e-10 41.1 8.0 2.0 2 0 0 2 2 2 1 Ion channel 60KD_IMP PF02096.20 KER33936.1 - 1.9 8.3 6.3 1.7 8.5 0.3 3.1 2 1 0 3 3 3 0 60Kd inner membrane protein BTB_2 PF02214.22 KER33937.1 - 2.4e-13 50.2 0.0 6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DpnI_C PF17726.1 KER33937.1 - 0.022 14.9 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain Pyridoxal_deC PF00282.19 KER33938.1 - 1.6e-69 234.4 3.7 4.3e-51 173.8 1.5 5.4 3 2 2 5 5 5 4 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 KER33938.1 - 0.0099 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF4229 PF14012.6 KER33938.1 - 0.019 15.1 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Pyridoxal_deC PF00282.19 KER33939.1 - 2.3e-22 79.3 0.0 3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.19 KER33940.1 - 4.8e-38 130.8 0.0 6.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L19e PF01280.20 KER33942.1 - 3.4e-62 208.8 8.9 3.4e-62 208.8 8.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e FAP PF07174.11 KER33942.1 - 3.5 7.0 34.6 5.3 6.4 34.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Spc29 PF17082.5 KER33942.1 - 6.2 6.6 11.0 0.044 13.6 1.5 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 Pkinase PF00069.25 KER33945.1 - 6e-42 143.8 0.0 1e-41 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33945.1 - 9.5e-28 97.2 0.0 1.8e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KER33945.1 - 0.00018 21.0 4.7 0.00058 19.3 4.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 KER33945.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KER33945.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIT PF04212.18 KER33945.1 - 0.026 14.6 1.3 0.069 13.2 1.3 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RA PF00788.23 KER33948.1 - 6.5e-11 42.7 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Nore1-SARAH PF16517.5 KER33948.1 - 4.7e-09 36.0 2.7 1.2e-08 34.7 2.7 1.7 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 KER33948.1 - 0.00029 20.7 14.5 0.00052 19.9 14.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ras_bdg_2 PF14847.6 KER33948.1 - 0.024 15.0 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Pkinase PF00069.25 KER33949.1 - 1.7e-60 204.7 0.0 5.5e-60 203.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER33949.1 - 1.6e-32 112.8 0.2 1.8e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KER33949.1 - 1.5e-06 28.8 0.3 5.3e-06 27.0 0.2 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KER33949.1 - 0.00015 21.2 0.2 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KER33949.1 - 0.00016 20.7 0.1 0.00025 20.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KER33949.1 - 0.00035 20.0 0.0 0.00083 18.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KER33949.1 - 0.0013 18.7 0.1 0.032 14.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KER33949.1 - 0.03 13.1 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 KER33950.1 - 1e-33 114.9 0.1 1.4e-15 56.9 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KER33950.1 - 0.012 15.7 0.3 4.7 7.3 0.0 2.7 2 1 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 KER33950.1 - 0.023 14.8 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 KER33950.1 - 0.12 12.0 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Golgin_A5 PF09787.9 KER33951.1 - 0.0037 16.8 2.9 0.0037 16.8 2.9 6.9 2 1 3 6 6 6 3 Golgin subfamily A member 5 KH_1 PF00013.29 KER33953.1 - 4.7e-12 45.6 0.0 4.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_9 PF17904.1 KER33953.1 - 7e-05 23.1 0.1 0.00026 21.3 0.0 2.0 2 0 0 2 2 2 1 FMRP KH0 domain P2X_receptor PF00864.19 KER33954.1 - 2.3e-146 487.6 0.7 3e-146 487.2 0.7 1.1 1 0 0 1 1 1 1 ATP P2X receptor G0-G1_switch_2 PF15103.6 KER33954.1 - 0.012 16.1 0.2 0.024 15.1 0.2 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 MAT1 PF06391.13 KER33954.1 - 0.012 15.4 4.2 0.02 14.7 4.2 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 WAP PF00095.21 KER33954.1 - 1.3 9.4 4.8 9.3 6.7 0.6 3.0 3 0 0 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Arm PF00514.23 KER33955.1 - 3.4e-55 182.5 25.1 2.1e-06 27.5 0.0 14.0 14 0 0 14 14 14 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KER33955.1 - 6.6e-15 55.3 6.8 0.0084 16.5 0.1 7.7 4 4 6 10 10 10 5 HEAT repeats Adaptin_N PF01602.20 KER33955.1 - 4.4e-09 35.4 0.7 0.0013 17.4 0.0 3.6 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 KER33955.1 - 4.9e-07 29.5 7.3 3.4 8.2 0.1 6.7 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KER33955.1 - 6.5e-06 26.3 1.2 6.6 6.8 0.0 4.8 2 1 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KER33955.1 - 9.6e-06 26.0 12.6 0.094 13.3 0.2 7.4 8 2 2 10 10 10 3 HEAT-like repeat KAP PF05804.12 KER33955.1 - 5.4e-05 21.6 0.4 0.41 8.7 0.0 3.9 3 1 0 4 4 4 2 Kinesin-associated protein (KAP) RICTOR_N PF14664.6 KER33955.1 - 0.12 11.3 1.2 1.9 7.4 0.0 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term WD40 PF00400.32 KER33956.1 - 1.3e-07 32.2 9.0 0.0017 19.1 1.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER33956.1 - 4.4e-06 26.9 0.1 0.67 10.3 0.0 5.0 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER33956.1 - 0.022 13.7 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UQ_con PF00179.26 KER33957.1 - 5.9e-33 113.5 0.0 4.7e-32 110.6 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme F-box PF00646.33 KER33957.1 - 7.6e-10 38.4 0.7 2.5e-09 36.8 0.7 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KER33957.1 - 8.9e-08 32.0 0.2 2.1e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KER33957.1 - 1.3e-07 31.4 0.1 3.9e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KER33957.1 - 0.002 18.1 0.8 0.0089 16.0 0.8 2.0 2 0 0 2 2 2 1 F-box-like domain RWD PF05773.22 KER33957.1 - 0.021 15.1 0.2 0.5 10.7 0.0 2.4 2 0 0 2 2 2 0 RWD domain zf-Sec23_Sec24 PF04810.15 KER33957.1 - 0.78 9.8 6.8 5.3 7.2 0.0 3.8 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger AAA_12 PF13087.6 KER33961.1 - 5.5e-39 133.8 0.0 1.1e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 KER33961.1 - 9.2e-35 120.3 0.0 2e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 KER33961.1 - 1.6e-28 100.2 0.6 6.2e-16 59.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KER33961.1 - 3.5e-15 56.2 0.0 8.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KER33961.1 - 4.6e-12 46.5 0.0 8.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KER33961.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KER33961.1 - 0.00013 21.8 0.5 0.87 9.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KER33961.1 - 0.00052 20.1 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KER33961.1 - 0.0015 18.1 0.0 0.027 14.0 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KER33961.1 - 0.0049 16.7 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 Helicase MobB PF03205.14 KER33961.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 KER33961.1 - 0.021 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KER33961.1 - 0.054 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 KER33961.1 - 0.057 12.6 0.1 0.5 9.5 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase DUF853 PF05872.12 KER33961.1 - 0.081 11.5 0.2 0.13 10.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 KER33961.1 - 0.095 13.1 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KER33961.1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KER33961.1 - 0.15 11.1 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 KER33961.1 - 0.15 11.2 0.0 0.87 8.8 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ANAPC4_WD40 PF12894.7 KER33962.1 - 0.0047 17.2 0.1 0.55 10.6 0.0 3.7 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KER33962.1 - 0.052 14.4 11.8 35 5.5 0.0 5.6 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF2749 PF10907.8 KER33962.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Ank_2 PF12796.7 KER33963.1 - 0.0047 17.5 0.0 0.023 15.3 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) BBS2_C PF14782.6 KER33964.1 - 0.0093 14.8 0.0 0.17 10.6 0.0 2.1 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal CBM46 PF18448.1 KER33964.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain SAM_2 PF07647.17 KER33966.1 - 1.8e-10 40.8 0.1 6.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NOA36 PF06524.12 KER33966.1 - 0.00086 18.7 12.4 0.0028 17.0 11.5 1.9 2 0 0 2 2 2 1 NOA36 protein SAM_1 PF00536.30 KER33966.1 - 0.0016 18.8 0.4 0.74 10.3 0.0 2.7 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) Utp14 PF04615.13 KER33966.1 - 0.045 12.4 7.5 0.067 11.8 7.5 1.2 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 KER33966.1 - 0.05 11.7 13.3 0.077 11.1 13.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KER33966.1 - 0.051 14.0 21.7 0.13 12.7 21.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 KER33966.1 - 0.097 12.2 6.4 0.25 10.9 6.4 1.7 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 KER33966.1 - 0.3 10.5 7.7 0.49 9.8 7.7 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 KER33966.1 - 0.34 10.9 6.7 0.72 9.9 6.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Osteopontin PF00865.18 KER33966.1 - 0.93 8.9 19.5 2 7.8 19.5 1.6 1 0 0 1 1 1 0 Osteopontin ANAPC15 PF15243.6 KER33966.1 - 1.1 9.7 13.4 2.6 8.5 13.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.14 KER33966.1 - 1.6 7.0 10.0 2.4 6.3 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KER33966.1 - 2.7 7.8 8.4 5.2 6.9 8.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 KER33966.1 - 3.1 6.2 11.2 5.9 5.3 11.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KER33966.1 - 3.6 5.7 9.7 5.2 5.1 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 KER33966.1 - 4.3 7.0 5.5 9.9 5.8 5.5 1.6 1 0 0 1 1 1 0 FAM176 family CBS PF00571.28 KER33967.1 - 9e-37 125.3 2.3 3.6e-11 43.3 0.2 4.3 4 0 0 4 4 4 4 CBS domain IBP39 PF11422.8 KER33967.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Initiator binding protein 39 kDa TmoB PF06234.12 KER33967.1 - 0.11 12.5 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) HhH-GPD PF00730.25 KER33969.1 - 2.1e-20 73.2 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KER33969.1 - 0.00022 20.9 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KER33969.1 - 0.02 15.2 2.0 0.036 14.4 2.0 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III NUDIX_4 PF14815.6 KER33970.1 - 1.4e-12 47.5 0.0 2.4e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Myotub-related PF06602.14 KER33971.1 - 1.1e-165 550.8 0.0 1.2e-126 422.4 0.0 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain GRAM PF02893.20 KER33971.1 - 8.1e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 KER33971.1 - 0.00065 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KER33971.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KER33971.1 - 0.0087 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family 3-PAP PF12578.8 KER33971.1 - 0.028 14.2 0.3 0.13 12.0 0.1 2.3 3 0 0 3 3 3 0 Myotubularin-associated protein DUF5528 PF17666.1 KER33971.1 - 0.14 12.1 0.1 25 4.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5528) RVT_1 PF00078.27 KER33972.1 - 1.4e-29 103.2 0.0 3.9e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-GRF PF06839.12 KER33972.1 - 0.015 15.4 1.0 0.032 14.3 1.0 1.6 1 0 0 1 1 1 0 GRF zinc finger Pap_E4 PF02711.14 KER33976.1 - 5.4 8.0 8.7 1.1 10.2 0.9 2.9 2 0 0 2 2 2 0 E4 protein Y_phosphatase PF00102.27 KER33977.1 - 3.2e-67 226.5 0.0 1.3e-66 224.5 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 KER33977.1 - 4.5e-14 52.5 0.0 8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KER33977.1 - 0.0062 16.7 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSPc PF00782.20 KER33977.1 - 0.032 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER33977.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KER33977.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Amb_V_allergen PF03913.13 KER33977.1 - 0.29 11.1 1.5 0.48 10.4 0.2 2.0 2 0 0 2 2 2 0 Amb V Allergen DASH_Spc34 PF08657.10 KER33979.1 - 0.058 13.2 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 WD40 PF00400.32 KER33980.1 - 8.9e-12 45.3 10.9 0.0023 18.7 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 KER33980.1 - 1e-07 31.6 1.4 0.63 10.4 0.0 5.4 4 0 0 4 4 4 3 HEAT repeat Pkinase PF00069.25 KER33980.1 - 5.6e-05 22.6 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain RRM_1 PF00076.22 KER33981.1 - 5.8e-24 83.7 0.0 1.3e-10 41.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 KER33981.1 - 2e-11 44.0 0.0 3.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 KER33981.1 - 5.7e-07 29.5 0.0 0.042 13.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 KER33981.1 - 2.5e-05 24.3 0.0 0.0074 16.4 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KER33981.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Hydrolase_4 PF12146.8 KER33983.1 - 3e-10 39.8 0.0 4.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KER33983.1 - 1.1e-05 26.1 2.2 0.00032 21.4 0.0 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KER33983.1 - 0.00035 20.1 0.0 0.0047 16.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KER33983.1 - 0.0011 18.7 0.0 0.54 9.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 KER33983.1 - 0.0012 17.8 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) RuvX PF03652.15 KER33983.1 - 0.024 15.0 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Holliday junction resolvase DLH PF01738.18 KER33983.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KER33984.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KER33984.1 - 0.042 13.1 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FSH1 PF03959.13 KER33984.1 - 0.12 12.0 0.0 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) GIY-YIG PF01541.24 KER33985.1 - 0.00061 20.0 0.2 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain DUF885 PF05960.11 KER33985.1 - 0.071 12.7 0.2 0.081 12.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4346 PF14251.6 KER33985.1 - 0.13 12.3 0.6 8.2 6.5 0.0 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4346) Adap_comp_sub PF00928.21 KER33986.1 - 4.3e-64 216.4 0.0 5.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KER33986.1 - 2.3e-06 27.6 1.1 4.3e-05 23.5 1.1 2.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Y_phosphatase PF00102.27 KER33987.1 - 1.3e-139 463.5 0.0 4.4e-74 249.0 0.1 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 KER33987.1 - 5.1e-07 29.6 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KER33987.1 - 0.00078 19.5 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KER33987.1 - 0.0012 19.0 0.1 1.9 8.6 0.0 3.0 3 0 0 3 3 3 2 Inositol hexakisphosphate fn3 PF00041.21 KER33988.1 - 5.4e-30 103.6 12.7 2.1e-13 50.4 1.7 6.6 7 0 0 7 7 7 5 Fibronectin type III domain Interfer-bind PF09294.10 KER33988.1 - 9.2e-05 22.7 0.1 0.48 10.8 0.0 3.4 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III Pur_ac_phosph_N PF16656.5 KER33988.1 - 0.00048 20.6 2.7 21 5.8 0.0 4.7 4 1 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KER33990.1 - 2.7e-17 62.9 0.3 6.5e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KER33990.1 - 1.6e-05 25.4 0.0 0.008 16.7 0.0 2.6 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain TackOD1 PF18551.1 KER33990.1 - 2.8 7.6 5.6 0.43 10.2 0.3 2.0 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-LITAF-like PF10601.9 KER33990.1 - 4.6 7.6 8.6 0.091 13.0 1.1 2.0 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain I-set PF07679.16 KER33991.1 - 6.1e-35 119.2 0.0 7.1e-15 54.8 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 KER33991.1 - 1.3e-34 118.6 0.4 1.2e-13 51.5 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 KER33991.1 - 8.7e-23 80.5 0.0 1.5e-07 31.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 KER33991.1 - 1e-18 67.3 0.0 2.5e-05 24.4 0.0 4.1 3 1 0 3 3 3 3 Immunoglobulin domain fn3 PF00041.21 KER33991.1 - 7.6e-11 42.2 0.8 4.5e-05 23.7 0.0 4.5 3 1 0 3 3 3 3 Fibronectin type III domain V-set PF07686.17 KER33991.1 - 1.4e-06 28.5 0.3 0.036 14.2 0.0 4.7 4 1 0 4 4 4 2 Immunoglobulin V-set domain DUF1505 PF07403.11 KER33992.1 - 0.023 14.9 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) RabGAP-TBC PF00566.18 KER33993.1 - 5.1e-30 104.7 2.4 1.1e-29 103.6 2.2 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KER33993.1 - 0.0016 17.9 0.0 1.5 8.3 0.0 2.2 1 1 1 2 2 2 2 Rab-binding domain (RBD) Pept_S41_N PF18294.1 KER33993.1 - 0.01 15.8 0.5 0.027 14.5 0.5 1.7 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain JmjC PF02373.22 KER33994.1 - 2.7e-40 137.3 0.1 6.5e-40 136.1 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KER33994.1 - 1.1e-11 44.5 0.1 2.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 KER33994.1 - 6.9e-09 35.9 14.6 0.00026 21.1 4.1 4.0 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD_2 PF13831.6 KER33994.1 - 1.3e-05 24.6 2.0 1.3e-05 24.6 2.0 3.7 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.6 KER33994.1 - 3.3e-05 24.0 3.5 3.3e-05 24.0 3.5 3.8 4 1 1 5 5 5 1 PHD-like zinc-binding domain C1_1 PF00130.22 KER33994.1 - 0.00092 19.1 15.4 0.024 14.5 0.2 3.4 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) 2-oxogl_dehyd_N PF16078.5 KER33994.1 - 0.025 14.2 1.3 0.058 13.0 1.3 1.6 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Tudor_2 PF18104.1 KER33994.1 - 0.16 11.7 0.1 0.52 10.0 0.1 2.0 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain PHD PF00628.29 KER33994.1 - 0.28 11.1 25.5 0.047 13.6 5.8 4.0 3 1 0 3 3 3 0 PHD-finger ADK PF00406.22 KER33995.1 - 3.2e-18 66.3 0.0 4.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KER33995.1 - 3.9e-10 40.3 0.0 7.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KER33995.1 - 0.0045 17.2 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KER33995.1 - 0.012 15.6 0.0 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 KER33995.1 - 0.049 13.9 0.0 7.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 KER33995.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 KER33995.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KER33995.1 - 0.1 13.0 0.0 0.39 11.1 0.0 2.1 1 1 0 1 1 1 0 RNA helicase KTI12 PF08433.10 KER33995.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KER33995.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.21 KER33996.1 - 0.00061 19.2 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Shisa PF13908.6 KER33996.1 - 0.062 13.6 12.0 0.064 13.5 6.4 2.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PX PF00787.24 KER33997.1 - 1.5e-14 54.0 0.0 4.6e-14 52.4 0.0 1.8 1 1 0 1 1 1 1 PX domain zf-TAZ PF02135.16 KER33997.1 - 6.9 7.2 8.0 20 5.7 0.2 3.1 3 0 0 3 3 3 0 TAZ zinc finger Ank_2 PF12796.7 KER33998.1 - 9.2e-26 90.3 6.6 3.4e-08 34.0 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER33998.1 - 1.3e-18 66.8 9.1 2e-06 27.9 0.1 6.2 2 1 6 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER33998.1 - 5e-18 63.3 5.9 0.0022 18.3 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 KER33998.1 - 7.6e-18 64.6 9.9 1.7e-05 25.2 0.1 6.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Patatin PF01734.22 KER33998.1 - 4.6e-16 59.6 0.9 3.1e-15 56.9 0.9 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ank PF00023.30 KER33998.1 - 6.1e-15 54.9 23.6 0.00019 21.7 0.1 8.3 8 1 0 8 8 8 4 Ankyrin repeat HMG_box_2 PF09011.10 KER33999.1 - 5.5e-09 36.5 7.3 6.4e-09 36.3 4.9 2.2 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.19 KER33999.1 - 2.2e-08 34.4 7.7 1.6e-05 25.2 4.1 2.8 1 1 1 2 2 2 2 HMG (high mobility group) box Adeno_E1B_19K PF01691.16 KER33999.1 - 0.015 14.8 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Phage_TAC_5 PF08890.11 KER33999.1 - 3.5 7.6 6.8 8.3 6.4 5.3 2.0 1 1 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC DUF1908 PF08926.11 KER34000.1 - 2.6e-73 246.6 0.0 2.6e-73 246.6 0.0 4.5 3 1 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 KER34000.1 - 4.1e-59 200.1 0.0 5.9e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER34000.1 - 7.4e-28 97.5 0.0 1.9e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 KER34000.1 - 1.7e-09 37.4 0.0 3.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KER34000.1 - 1.4e-08 34.9 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 KER34000.1 - 4.5e-05 23.5 0.0 0.012 15.5 0.1 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PDZ_2 PF13180.6 KER34000.1 - 7.3e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.6 KER34000.1 - 0.00044 19.7 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KER34000.1 - 0.0051 15.8 0.3 0.0051 15.8 0.3 2.5 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_C PF00433.24 KER34000.1 - 0.043 14.5 3.3 1.1 10.0 3.3 3.6 1 1 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KER34000.1 - 0.053 12.3 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase SPATA1_C PF15743.5 KER34002.1 - 6.2e-08 32.9 12.1 1.5e-07 31.6 12.1 1.6 1 1 0 1 1 1 1 Spermatogenesis-associated C-terminus SPATA1_C PF15743.5 KER34003.1 - 2.6e-15 56.8 38.2 2.6e-15 56.8 38.2 2.6 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus OmpH PF03938.14 KER34003.1 - 0.0089 16.4 12.9 0.0089 16.4 12.9 3.6 2 1 1 3 3 3 1 Outer membrane protein (OmpH-like) CHD5 PF04420.14 KER34003.1 - 1.3 8.8 10.0 0.14 12.0 0.6 3.1 2 1 0 3 3 3 0 CHD5-like protein FlaC_arch PF05377.11 KER34003.1 - 2.1 8.8 7.7 30 5.1 0.2 3.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) zf-BED PF02892.15 KER34005.1 - 2.4e-05 24.3 0.4 4.8e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 KER34007.1 - 6.6e-09 35.4 0.1 1.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Dimer_Tnp_hAT PF05699.14 KER34008.1 - 8.2e-08 31.9 0.0 3.6e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 KER34008.1 - 7.6e-07 29.1 0.3 1.9e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger TF_AP-2 PF03299.14 KER34011.1 - 1.2e-42 146.2 0.1 1.9e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 Transcription factor AP-2 CNPase PF05881.12 KER34012.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) SRF-TF PF00319.18 KER34012.1 - 0.076 12.5 1.5 0.15 11.6 1.5 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-H2C2_5 PF13909.6 KER34013.1 - 2.5e-08 33.5 7.8 8.7e-06 25.4 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain OrsD PF12013.8 KER34013.1 - 0.0013 19.1 0.8 0.079 13.4 0.2 2.5 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 KER34013.1 - 0.0087 15.6 0.6 0.023 14.2 0.1 2.0 1 1 1 2 2 2 1 Zinc-finger C2H2-type zf-met2 PF12907.7 KER34013.1 - 0.04 14.0 2.6 0.058 13.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding zf_C2H2_ZHX PF18387.1 KER34013.1 - 0.053 13.2 6.0 0.21 11.3 0.2 3.1 2 2 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 KER34013.1 - 0.12 12.7 1.6 0.42 10.9 1.6 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding RMP PF14996.6 KER34013.1 - 0.33 11.2 5.2 0.37 11.0 1.1 2.5 2 1 1 3 3 3 0 Retinal Maintenance zf-C2H2 PF00096.26 KER34013.1 - 0.96 10.0 5.8 18 6.1 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER34013.1 - 1.9 9.5 5.5 37 5.5 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KER34013.1 - 2.5 8.5 6.4 8.2 6.8 0.5 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Homeodomain PF00046.29 KER34014.1 - 9.7e-06 25.3 0.9 0.005 16.7 0.1 2.4 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 KER34014.1 - 0.00017 21.4 1.9 0.037 13.9 0.2 2.6 2 0 0 2 2 2 2 Homeobox KN domain PI3_PI4_kinase PF00454.27 KER34015.1 - 6.6e-21 75.3 0.0 5.1e-19 69.1 0.0 2.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RVT_1 PF00078.27 KER34015.1 - 4.3e-19 68.9 0.0 4.9e-11 42.6 0.0 3.6 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) FATC PF02260.20 KER34015.1 - 4.6e-09 36.0 0.0 1.6e-08 34.2 0.0 2.1 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KER34015.1 - 0.015 14.5 7.5 0.15 11.2 0.6 3.0 3 0 0 3 3 3 0 FAT domain AKAP28 PF14469.6 KER34016.1 - 5.5e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor Ig_3 PF13927.6 KER34020.1 - 6.8e-13 49.0 13.3 0.00065 20.3 0.1 6.5 6 1 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 KER34020.1 - 1.5e-07 31.5 3.2 0.024 14.8 0.1 4.9 4 0 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 KER34020.1 - 2.1e-06 27.7 2.2 0.48 10.5 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin I-set domain zf-C2H2 PF00096.26 KER34022.1 - 6.5e-13 48.4 35.0 0.00039 20.7 2.0 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER34022.1 - 4.9e-08 33.1 4.1 1.3e-06 28.6 0.8 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KER34022.1 - 0.34 11.9 30.6 3.2 8.9 1.7 6.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KER34022.1 - 0.75 9.9 7.4 4.6 7.3 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KER34022.1 - 1.8 9.2 22.0 0.19 12.4 0.7 5.1 4 1 2 6 6 6 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KER34022.1 - 4.2 7.7 11.6 0.54 10.6 2.3 3.1 2 1 0 2 2 2 0 C2H2-type zinc ribbon RBD-FIP PF09457.10 KER34023.1 - 4.5e-10 39.3 0.4 2e-09 37.2 0.4 2.2 1 0 0 1 1 1 1 FIP domain EF-hand_7 PF13499.6 KER34023.1 - 1.2e-08 35.2 0.1 1.2e-08 35.2 0.1 3.6 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KER34023.1 - 1.2e-06 28.0 3.1 0.018 14.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KER34023.1 - 8.6e-06 24.9 4.9 0.045 13.3 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KER34023.1 - 0.0005 19.9 4.4 0.28 11.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair PRA-PH PF01503.17 KER34023.1 - 0.072 13.5 7.0 3.1 8.3 0.3 2.7 1 1 1 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Nbl1_Borealin_N PF10444.9 KER34023.1 - 0.075 12.7 7.3 0.55 9.9 0.2 3.0 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal SSXT PF05030.12 KER34023.1 - 0.081 12.6 0.8 0.59 9.8 0.2 2.4 2 0 0 2 2 2 0 SSXT protein (N-terminal region) MapZ_EC1 PF18041.1 KER34023.1 - 0.15 12.3 4.0 8.2 6.7 0.2 2.9 3 0 0 3 3 3 0 MapZ extracellular domain 1 Glyoxalase PF00903.25 KER34023.1 - 0.21 11.8 0.8 0.35 11.0 0.8 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Bac_small_YrzI PF09501.10 KER34023.1 - 0.42 10.8 10.5 0.23 11.6 5.3 2.9 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Peptidase_S46 PF10459.9 KER34023.1 - 0.62 8.6 12.8 1.2 7.7 12.8 1.4 1 1 0 1 1 1 0 Peptidase S46 SAS4 PF15460.6 KER34023.1 - 2 8.5 16.9 1.5 9.0 7.5 3.1 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 V-SNARE PF05008.15 KER34023.1 - 3.6 8.0 15.2 0.53 10.7 0.1 3.7 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-CCCH_2 PF14608.6 KER34024.1 - 0.17 12.4 0.7 0.17 12.4 0.7 2.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger SMC_N PF02463.19 KER34025.1 - 1e-55 188.6 8.9 2.2e-28 99.2 1.4 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KER34025.1 - 2.2e-25 89.2 0.1 2.2e-25 89.2 0.1 3.3 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KER34025.1 - 9.3e-13 48.6 1.9 2.1e-05 24.5 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KER34025.1 - 8.1e-10 38.9 3.9 8.1e-10 38.9 3.9 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 KER34025.1 - 2.7e-07 31.3 20.4 2.7e-07 31.3 20.4 7.0 4 2 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KER34025.1 - 0.00011 21.8 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KER34025.1 - 0.00015 22.3 18.1 0.038 14.5 0.0 5.8 4 2 1 5 5 5 2 ABC transporter DUF948 PF06103.11 KER34025.1 - 0.01 16.1 4.3 0.01 16.1 4.3 5.8 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) ABC_transp_aux PF09822.9 KER34026.1 - 9.8e-09 35.1 0.5 2.2e-08 33.9 0.1 1.7 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 KER34026.1 - 0.018 13.9 0.0 0.12 11.2 0.0 2.2 2 1 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta Mito_carr PF00153.27 KER34027.1 - 5.5e-62 205.7 3.1 3.1e-23 81.5 0.2 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein rve PF00665.26 KER34027.1 - 1.9e-12 47.4 0.0 3.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KER34027.1 - 2.2e-11 43.7 0.3 3.9e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Fuseless PF15993.5 KER34027.1 - 0.019 14.1 0.5 0.43 9.7 0.1 2.2 2 0 0 2 2 2 0 Fuseless GTP_EFTU PF00009.27 KER34029.1 - 3.8e-43 147.3 0.0 5.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KER34029.1 - 1.5e-17 63.9 0.0 2.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KER34029.1 - 5.6e-06 26.4 0.2 0.025 14.7 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KER34029.1 - 0.09 12.3 0.3 12 5.4 0.0 3.0 2 1 1 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.20 KER34029.1 - 0.2 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KER34029.1 - 0.21 10.9 0.0 0.83 9.0 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family TPR_2 PF07719.17 KER34030.1 - 0.0043 17.1 0.5 1.4 9.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat CCB1 PF12046.8 KER34030.1 - 2.5 7.4 5.4 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Exo_endo_phos PF03372.23 KER34031.1 - 4.1e-08 33.0 0.1 6.1e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KER34031.1 - 0.0039 17.0 0.0 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DSHCT PF08148.12 KER34033.1 - 6.8e-38 129.9 0.1 2.2e-37 128.2 0.1 1.8 1 1 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KER34033.1 - 6.9e-17 61.8 0.1 1.6e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KER34033.1 - 4.3e-09 36.6 0.0 7.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KER34033.1 - 6.1e-05 23.3 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KER34033.1 - 0.00089 19.5 0.3 0.008 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KER34033.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 KER34033.1 - 0.062 13.3 0.2 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain BAG6 PF12057.8 KER34033.1 - 0.14 11.9 0.3 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 BCL2-associated athanogene 6 Exonuc_VII_L PF02601.15 KER34033.1 - 0.18 11.3 0.9 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tir_receptor_C PF07489.11 KER34033.1 - 0.19 11.7 1.9 0.49 10.3 0.5 2.3 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Gmad2 PF10648.9 KER34033.1 - 0.2 11.9 0.4 55 4.1 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin-like domain of bacterial spore germination ALMS_motif PF15309.6 KER34034.1 - 0.1 13.1 0.8 0.15 12.5 0.8 1.4 1 1 0 1 1 1 0 ALMS motif MAP17 PF15807.5 KER34035.1 - 0.73 10.1 7.9 2.5 8.3 0.1 3.3 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Axin_b-cat_bind PF08833.10 KER34036.1 - 0.0017 18.4 0.2 0.004 17.2 0.2 1.6 1 0 0 1 1 1 1 Axin beta-catenin binding domain MMR_HSR1 PF01926.23 KER34039.1 - 2.4e-19 69.5 0.0 4.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KER34039.1 - 6e-09 35.6 0.7 1.3e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KER34039.1 - 2.7e-06 26.9 0.1 5.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KER34039.1 - 3.3e-06 27.3 0.0 0.033 14.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KER34039.1 - 0.00012 21.7 0.9 0.0056 16.2 0.9 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER34039.1 - 0.00076 19.4 0.1 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase Arf PF00025.21 KER34039.1 - 0.00084 18.8 0.1 0.0036 16.8 0.1 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KER34039.1 - 0.0082 16.4 0.1 0.02 15.1 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KER34039.1 - 0.02 15.2 0.0 0.11 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 KER34039.1 - 0.035 13.7 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 KER34039.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsJ PF01728.19 KER34040.1 - 4.8e-66 222.2 0.0 6.8e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PIG-S PF10510.9 KER34041.1 - 3.1e-57 194.6 1.5 4.1e-57 194.2 1.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Gar1 PF04410.14 KER34042.1 - 2.7e-30 105.2 0.0 8.1e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region MBOAT PF03062.19 KER34043.1 - 3e-30 105.7 23.8 9.7e-30 104.1 23.8 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KER34043.1 - 0.0049 17.1 3.8 0.016 15.4 3.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RVT_1 PF00078.27 KER34044.1 - 2.6e-10 40.2 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L10 PF00466.20 KER34045.1 - 5e-21 74.7 0.2 9.8e-21 73.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KER34045.1 - 1.7e-19 69.5 0.2 3.4e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KER34045.1 - 2.3e-10 40.9 1.1 4.9e-08 33.4 0.7 2.6 2 0 0 2 2 2 2 60s Acidic ribosomal protein RVT_1 PF00078.27 KER34045.1 - 2.2e-09 37.1 0.0 9.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4 PF00105.18 KER34046.1 - 1.7e-09 38.0 2.8 1.9e-09 37.8 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Exo_endo_phos_2 PF14529.6 KER34046.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.32 KER34047.1 - 0.008 17.0 0.0 12 6.9 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat YBD PF17725.1 KER34049.1 - 6.8e-74 248.2 0.1 1e-73 247.7 0.1 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 KER34049.1 - 5.2e-26 90.5 0.1 1.1e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Lipoprotein_X PF03305.13 KER34049.1 - 0.095 12.5 0.2 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein DUF5524 PF17662.1 KER34051.1 - 3e-13 49.8 1.3 6.6e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5524) MFS_1 PF07690.16 KER34053.1 - 0.00075 18.5 1.5 0.00092 18.2 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KER34054.1 - 0.00045 19.2 31.0 0.034 13.1 25.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KER34055.1 - 1.1e-12 47.6 35.8 1.1e-12 47.6 35.8 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KER34056.1 - 2e-13 50.0 16.4 2e-13 50.0 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KER34057.1 - 4.3e-21 75.2 29.3 6.2e-19 68.1 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dcc1 PF09724.9 KER34058.1 - 2.7e-69 234.0 0.3 1.5e-57 195.4 0.0 2.3 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 Closter_coat PF01785.17 KER34058.1 - 0.0023 17.2 0.0 4.4 6.5 0.0 3.1 3 0 0 3 3 3 2 Closterovirus coat protein DUF1381 PF07129.11 KER34058.1 - 0.16 11.8 3.8 12 5.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) Glyco_hydro_3 PF00933.21 KER34059.1 - 6e-38 131.0 0.0 1.8e-37 129.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KER34059.1 - 1.5e-25 90.4 0.0 8e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KER34059.1 - 1.5e-10 41.0 0.0 3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain XG_FTase PF03254.13 KER34060.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase MOZ_SAS PF01853.18 KER34061.1 - 6.1e-36 123.8 0.1 8.9e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KER34061.1 - 2.2e-14 52.8 0.3 5.4e-14 51.5 0.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain zf-C2HC PF01530.18 KER34061.1 - 2.4e-09 37.2 3.8 6.2e-09 35.9 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 KER34061.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1279 PF06916.13 KER34061.1 - 0.11 13.1 3.7 3.1 8.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1279) DUF2304 PF10066.9 KER34062.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) RVT_1 PF00078.27 KER34063.1 - 1.2e-06 28.2 0.1 4.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 KER34064.1 - 4.6e-07 30.4 5.7 0.055 14.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER34064.1 - 0.00011 22.4 0.2 8.1 6.8 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KER34064.1 - 0.049 12.9 0.2 14 4.9 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain HLH PF00010.26 KER34066.1 - 1.6e-16 60.0 1.1 2.7e-16 59.3 1.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YdjO PF14169.6 KER34066.1 - 0.028 14.1 0.2 0.056 13.2 0.2 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO Tubulin_C PF03953.17 KER34067.1 - 1.7e-08 34.6 0.0 3.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_C PF03953.17 KER34068.1 - 8.1e-13 48.6 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KER34068.1 - 3.4e-05 24.1 0.0 6.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DUF4949 PF16307.5 KER34068.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) Prenyltransf PF01255.19 KER34070.1 - 6e-67 225.5 0.0 7.7e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CTD_bind PF04818.13 KER34071.1 - 1.9e-11 44.6 0.1 9.2e-11 42.4 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KER34071.1 - 3.9e-09 36.2 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KER34071.1 - 0.0016 18.5 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 KER34071.1 - 0.0036 17.1 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif YjcZ PF13990.6 KER34071.1 - 0.0066 15.9 4.8 0.17 11.2 1.5 2.3 2 0 0 2 2 2 2 YjcZ-like protein PHM7_cyt PF14703.6 KER34071.1 - 0.0088 16.3 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF1318 PF07027.12 KER34071.1 - 0.11 13.0 0.1 32 5.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) SgrR_N PF12793.7 KER34071.1 - 1.1 9.5 5.1 9.1 6.5 0.3 3.2 3 0 0 3 3 3 0 Sugar transport-related sRNA regulator N-term RRM_1 PF00076.22 KER34073.1 - 1.7e-09 37.4 0.0 0.0059 16.4 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_TAC_13 PF16459.5 KER34073.1 - 0.17 12.3 0.0 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC Statherin PF03875.13 KER34073.1 - 9.2 6.5 7.0 26 5.0 7.0 1.8 1 0 0 1 1 1 0 Statherin SWIRM PF04433.17 KER34075.1 - 0.00028 21.1 0.0 0.00062 20.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain zf-CW PF07496.15 KER34075.1 - 0.003 17.5 8.3 0.01 15.8 8.3 2.0 1 0 0 1 1 1 1 CW-type Zinc Finger RVT_1 PF00078.27 KER34077.1 - 0.097 12.2 0.0 0.35 10.4 0.0 1.7 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 KER34078.1 - 2.9e-66 223.5 0.0 4.4e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER34078.1 - 3.9e-39 134.5 0.0 5.5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KER34078.1 - 8e-31 105.7 17.9 3.5e-15 55.6 4.2 2.9 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KER34078.1 - 1.2e-26 93.0 0.0 2.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 KER34078.1 - 5.9e-08 33.3 0.4 1.4e-07 32.1 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 KER34078.1 - 0.0013 19.0 19.1 0.0044 17.3 8.6 2.8 2 0 0 2 2 2 2 C1 domain Haspin_kinase PF12330.8 KER34078.1 - 0.0013 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KER34078.1 - 0.0074 15.6 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KER34078.1 - 0.074 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PHD_2 PF13831.6 KER34078.1 - 0.099 12.2 14.8 0.09 12.3 1.0 2.9 3 0 0 3 3 3 0 PHD-finger Kdo PF06293.14 KER34078.1 - 0.13 11.5 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KER34078.1 - 0.18 11.4 0.5 0.35 10.4 0.1 1.6 2 0 0 2 2 2 0 RIO1 family zf-RING-like PF08746.11 KER34078.1 - 1.3 9.4 18.0 1.7 9.1 3.6 2.9 2 0 0 2 2 2 0 RING-like domain zf-RING_9 PF13901.6 KER34078.1 - 1.7 8.6 14.6 3.8 7.4 3.6 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FYVE PF01363.21 KER34080.1 - 3.5e-19 68.7 11.4 1.2e-18 67.0 11.4 2.0 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 KER34080.1 - 3.8e-15 56.0 0.4 7.2e-10 38.9 0.0 3.0 3 0 0 3 3 3 2 RUN domain DUF745 PF05335.13 KER34080.1 - 0.0054 16.5 15.3 0.019 14.7 7.4 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF745) FPP PF05911.11 KER34080.1 - 0.019 13.2 25.9 0.013 13.7 10.7 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil StbA PF06406.11 KER34080.1 - 0.054 12.7 1.9 0.24 10.6 0.1 2.3 2 0 0 2 2 2 0 StbA protein IBR PF01485.21 KER34080.1 - 0.2 11.9 7.7 0.82 9.9 7.7 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ADIP PF11559.8 KER34080.1 - 3 7.9 31.5 0.063 13.4 6.5 3.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KER34080.1 - 3.3 8.0 21.6 0.48 10.7 0.7 4.4 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 KER34080.1 - 4.1 7.9 11.6 2.9 8.4 0.4 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 KER34080.1 - 4.7 7.0 17.3 1.3 8.8 0.5 3.8 3 1 0 3 3 3 0 USP8 interacting Filament PF00038.21 KER34080.1 - 5 6.6 29.2 5 6.6 8.9 3.8 2 1 1 3 3 3 0 Intermediate filament protein PRKG1_interact PF15898.5 KER34080.1 - 5.7 7.9 32.1 0.78 10.7 1.9 4.0 3 1 1 4 4 3 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 KER34080.1 - 5.9 6.1 16.5 0.76 9.1 8.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DZR PF12773.7 KER34080.1 - 7.7 6.6 16.4 64 3.7 7.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon Tup_N PF08581.10 KER34080.1 - 8.8 6.7 14.6 0.22 11.8 0.5 4.3 3 1 2 5 5 5 0 Tup N-terminal MscS_porin PF12795.7 KER34080.1 - 9.1 5.7 33.7 0.83 9.2 12.0 3.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain LSM14 PF12701.7 KER34081.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KER34081.1 - 0.0038 18.1 0.1 0.012 16.4 0.1 1.8 1 1 0 1 1 1 1 FDF domain AAR2 PF05282.11 KER34082.1 - 0.084 12.3 3.1 0.1 12.0 3.1 1.0 1 0 0 1 1 1 0 AAR2 protein I-set PF07679.16 KER34083.1 - 3.2e-54 180.9 0.0 9.2e-16 57.7 0.0 11.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Pkinase PF00069.25 KER34083.1 - 1.8e-51 175.0 0.0 1e-37 130.0 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 KER34083.1 - 5.1e-44 148.8 0.0 1.1e-09 38.7 0.0 10.2 9 0 0 9 9 9 7 Immunoglobulin domain ig PF00047.25 KER34083.1 - 1.2e-20 73.5 0.0 4e-05 23.7 0.0 8.5 8 0 0 8 8 8 3 Immunoglobulin domain Ig_2 PF13895.6 KER34083.1 - 1.4e-17 63.8 0.5 0.082 13.3 0.0 9.4 9 0 0 9 9 9 3 Immunoglobulin domain V-set PF07686.17 KER34083.1 - 2.7e-16 59.7 0.2 0.13 12.4 0.0 8.1 8 0 0 8 8 8 5 Immunoglobulin V-set domain fn3 PF00041.21 KER34083.1 - 1.6e-09 38.0 0.8 0.013 15.9 0.0 6.0 5 0 0 5 5 5 2 Fibronectin type III domain Izumo-Ig PF16706.5 KER34083.1 - 0.00015 21.7 0.5 9 6.4 0.0 5.2 5 0 0 5 5 5 1 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 KER34083.1 - 0.00023 21.1 0.1 53 4.0 0.0 5.7 6 0 0 6 6 6 0 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 KER34083.1 - 0.0016 18.6 0.1 6.7 7.0 0.0 3.8 4 0 0 4 4 4 2 Natural killer cell receptor 2B4 ADK PF00406.22 KER34084.1 - 1.9e-42 144.9 0.0 2.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KER34084.1 - 5.4e-20 72.2 0.0 9.5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KER34084.1 - 4.2e-16 58.6 0.0 1.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KER34084.1 - 8.1e-06 26.4 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KER34084.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 KER34084.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SPATA6 PF14909.6 KER34085.1 - 4.4e-37 127.3 0.0 6e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 ECSIT PF06239.11 KER34086.1 - 5.7e-62 208.8 0.1 1.1e-61 207.8 0.1 1.4 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway PITH PF06201.13 KER34086.1 - 1.2e-36 126.2 0.0 4.1e-36 124.5 0.0 2.0 2 0 0 2 2 2 1 PITH domain ECSIT_C PF14784.6 KER34086.1 - 8.5e-07 29.4 0.3 0.4 11.0 0.0 4.5 3 1 0 4 4 4 2 C-terminal domain of the ECSIT protein XPG_N PF00752.17 KER34086.1 - 7.1e-05 23.2 0.0 0.00017 22.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain GEMIN8 PF15348.6 KER34086.1 - 0.00016 22.1 2.0 0.00049 20.5 2.0 1.8 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 XPG_I_2 PF12813.7 KER34086.1 - 0.00098 18.7 0.3 0.011 15.2 0.5 2.2 2 0 0 2 2 2 1 XPG domain containing Rad21_Rec8_N PF04825.13 KER34087.1 - 5.1e-40 136.1 0.0 1.1e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KER34087.1 - 1e-15 56.7 0.1 5e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KER34087.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Ras PF00071.22 KER34088.1 - 1.4e-22 80.1 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER34088.1 - 4.7e-11 43.0 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KER34088.1 - 9.7e-07 28.5 0.0 7e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KER34088.1 - 0.00076 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KER34088.1 - 0.00081 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KER34088.1 - 0.0017 18.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KER34088.1 - 0.1 13.0 0.1 0.47 10.8 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 KER34088.1 - 0.13 12.3 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Terminase_GpA PF05876.12 KER34088.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ERCC3_RAD25_C PF16203.5 KER34089.1 - 6.6e-120 398.9 0.2 1.1e-119 398.1 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KER34089.1 - 3.9e-33 114.3 0.0 8.7e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER34089.1 - 1.8e-15 57.3 0.0 3.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KER34089.1 - 5.2e-10 39.7 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KER34089.1 - 0.0016 17.3 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNR_N PF08343.10 KER34089.1 - 0.039 14.0 0.4 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Kunitz_BPTI PF00014.23 KER34090.1 - 0.13 12.5 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Ski_Sno PF02437.17 KER34091.1 - 1e-36 125.0 0.1 1e-36 125.0 0.1 1.7 2 0 0 2 2 2 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 KER34091.1 - 6.6e-29 100.0 3.3 6.6e-29 100.0 3.3 1.9 2 0 0 2 2 2 1 c-SKI Smad4 binding domain PDCD2_C PF04194.13 KER34092.1 - 3.3e-32 112.0 2.7 6.7e-31 107.7 0.8 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 KER34092.1 - 2.4e-08 33.9 16.5 2.4e-08 33.9 16.5 3.0 2 1 0 2 2 2 1 MYND finger RVT_1 PF00078.27 KER34093.1 - 4.2e-39 134.4 0.0 6.6e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KER34093.1 - 1.1e-13 51.1 0.0 3.6e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KER34093.1 - 1.2e-07 31.5 0.1 2.3e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PHD PF00628.29 KER34094.1 - 0.00035 20.4 6.2 0.00076 19.3 6.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KER34094.1 - 0.13 12.3 2.9 0.33 10.9 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_Oberon PF07227.11 KER34094.1 - 0.25 11.2 6.1 0.43 10.5 6.1 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein C1_2 PF03107.16 KER34094.1 - 4.7 7.6 8.5 8.8 6.7 5.5 2.5 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 KER34094.1 - 5.2 7.0 7.8 1.5 8.7 3.8 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NTF2 PF02136.20 KER34095.1 - 5.6e-21 75.3 0.0 8.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Suc_Fer-like PF06999.12 KER34095.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like BET PF17035.5 KER34097.1 - 1.1e-25 89.5 0.2 2e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AF-4 PF05110.13 KER34097.1 - 0.011 13.9 15.3 0.013 13.6 15.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Bromodomain PF00439.25 KER34098.1 - 2.2e-11 43.6 0.1 1.2e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Bromodomain PF00439.25 KER34099.1 - 4.4e-18 65.1 0.1 7.1e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain GBP PF02263.19 KER34099.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain BET PF17035.5 KER34100.1 - 6e-25 87.2 0.4 1.1e-24 86.4 0.4 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AF-4 PF05110.13 KER34100.1 - 0.013 13.7 15.5 0.015 13.5 15.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Bromodomain PF00439.25 KER34101.1 - 2.2e-11 43.6 0.1 1.2e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Bromodomain PF00439.25 KER34102.1 - 4.4e-18 65.1 0.1 7.1e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain GBP PF02263.19 KER34102.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain 2-oxoacid_dh PF00198.23 KER34103.1 - 5e-65 219.2 0.1 6.5e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KER34103.1 - 2e-19 69.1 1.7 5.1e-19 67.9 1.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KER34103.1 - 3.5e-08 33.6 0.1 9e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KER34103.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KER34103.1 - 0.16 12.7 1.0 1.2 9.9 1.0 2.2 1 1 0 1 1 1 0 HlyD family secretion protein SNF2_N PF00176.23 KER34104.1 - 1.9e-74 250.5 1.7 3.6e-74 249.6 1.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KER34104.1 - 2.3e-21 75.7 1.3 5.5e-21 74.4 0.2 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KER34104.1 - 5.2e-20 71.9 0.0 2.1e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KER34104.1 - 6.3e-13 49.1 0.0 2.5e-12 47.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit QLQ PF08880.11 KER34104.1 - 2.6e-10 39.9 0.8 7.1e-10 38.5 0.8 1.8 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 KER34104.1 - 1.6e-09 38.2 3.9 1.6e-09 38.2 3.9 4.2 5 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.29 KER34104.1 - 2.9e-05 23.9 0.0 6.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase IF-2B PF01008.17 KER34105.1 - 4.6e-28 98.2 0.0 5.3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-C2H2 PF00096.26 KER34107.1 - 2.9e-12 46.3 31.9 0.0062 16.9 6.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KER34107.1 - 4.9e-11 42.5 30.0 0.00075 20.1 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KER34107.1 - 3e-10 40.0 32.6 7.3e-06 26.2 6.7 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KER34107.1 - 4.4e-05 23.7 28.2 0.0099 16.2 2.2 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KER34107.1 - 0.0021 18.0 2.1 0.0021 18.0 2.1 5.2 5 0 0 5 5 4 2 C2H2-type zinc finger zf_UBZ PF18439.1 KER34107.1 - 0.0039 16.7 14.5 6.3 6.5 0.2 4.7 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 KER34107.1 - 0.018 15.4 5.0 0.018 15.4 5.0 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type XPA_N PF01286.18 KER34107.1 - 0.05 13.6 11.2 5.3 7.2 0.0 4.4 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KER34107.1 - 0.063 13.4 14.4 1.7 8.8 4.6 4.5 3 1 1 4 4 4 0 Zinc ribbon domain CpXC PF14353.6 KER34107.1 - 0.077 13.0 9.1 12 6.0 0.1 4.0 2 1 1 3 3 3 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 KER34107.1 - 0.28 11.2 12.4 0.29 11.1 1.9 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain LIM PF00412.22 KER34107.1 - 0.35 11.1 15.9 13 6.1 10.4 3.6 2 1 1 3 3 3 0 LIM domain zf-C2HE PF16278.5 KER34107.1 - 0.81 10.2 24.8 0.64 10.5 0.2 5.4 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_12 PF11331.8 KER34107.1 - 1.4 8.8 6.2 2.7 7.9 1.3 2.9 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_4 PF13717.6 KER34107.1 - 2.5 8.1 17.6 14 5.8 0.1 4.3 3 1 0 3 3 3 0 zinc-ribbon domain zf-LYAR PF08790.11 KER34107.1 - 3.4 7.7 19.8 8.4 6.4 3.0 4.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_9 PF16293.5 KER34107.1 - 3.9 7.4 6.3 73 3.3 0.0 4.1 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-FCS PF06467.14 KER34107.1 - 4.5 7.3 15.6 19 5.3 7.1 4.2 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zinc-ribbons_6 PF07191.12 KER34107.1 - 5.7 7.0 11.9 65 3.6 0.1 3.7 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_15 PF17032.5 KER34107.1 - 8.9 7.1 11.5 27 5.6 6.3 3.3 2 1 2 4 4 4 0 zinc-ribbon family zinc_ribbon_10 PF10058.9 KER34107.1 - 9.1 6.1 9.4 25 4.7 1.7 3.6 3 1 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2_2 PF12756.7 KER34107.1 - 9.1 6.7 17.6 24 5.4 1.7 4.4 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 KER34107.1 - 9.2 6.3 11.6 16 5.6 1.3 3.2 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA pP_pnuc_2 PF18166.1 KER34108.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease CPSase_L_D3 PF02787.19 KER34108.1 - 0.03 14.7 0.4 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RhoGEF PF00621.20 KER34111.1 - 5.7e-18 65.8 0.0 7.7e-17 62.1 0.0 2.7 3 0 0 3 3 3 1 RhoGEF domain Golgin_A5 PF09787.9 KER34111.1 - 0.089 12.2 6.9 0.088 12.3 3.9 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KER34111.1 - 0.15 12.3 1.9 0.33 11.1 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KER34111.1 - 0.21 10.9 1.5 0.4 10.0 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Transcrip_act PF04949.13 KER34111.1 - 0.42 10.5 7.1 0.078 12.9 2.8 1.9 2 0 0 2 2 2 0 Transcriptional activator Rab5-bind PF09311.11 KER34111.1 - 0.59 9.5 10.7 0.53 9.6 7.2 2.3 2 0 0 2 2 2 0 Rabaptin-like protein Jnk-SapK_ap_N PF09744.9 KER34111.1 - 1.3 9.3 16.1 2.4 8.4 11.6 2.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DLP_helical PF18709.1 KER34111.1 - 6.5 5.9 6.7 29 3.7 4.2 2.2 2 0 0 2 2 2 0 Dynamin-like helical domain RNA_pol_Rpb1_1 PF04997.12 KER34114.1 - 2e-104 349.3 0.6 3.2e-104 348.6 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KER34114.1 - 6.3e-101 337.3 0.1 1.1e-100 336.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KER34114.1 - 2.6e-71 239.2 0.1 5.2e-71 238.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KER34114.1 - 1e-61 208.1 0.0 1.9e-61 207.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KER34114.1 - 9.9e-47 158.8 0.0 1.9e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KER34114.1 - 4e-44 149.9 1.9 8.7e-44 148.8 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KER34114.1 - 5.5e-37 126.0 0.4 1.8e-36 124.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 zf-CCHC PF00098.23 KER34115.1 - 3.1e-50 166.1 62.0 7.6e-09 35.3 2.2 6.6 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KER34115.1 - 2e-12 46.8 31.0 0.015 15.2 0.2 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KER34115.1 - 1.3e-07 31.2 42.9 0.033 13.9 0.8 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_5 PF14787.6 KER34115.1 - 1.8e-07 30.7 38.7 0.24 11.1 0.8 6.2 6 0 0 6 6 6 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KER34115.1 - 0.0011 18.7 47.9 0.12 12.2 3.2 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.6 KER34115.1 - 0.0016 18.2 43.9 2.4 8.1 1.2 6.4 6 0 0 6 6 6 6 Zinc knuckle Cnd2 PF05786.14 KER34118.1 - 5.3e-121 405.7 0.0 8.1e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 RVT_1 PF00078.27 KER34118.1 - 0.00037 20.1 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KER34119.1 - 5.9e-29 100.4 0.0 1.5e-28 99.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KER34119.1 - 1e-28 99.3 0.0 2.2e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KER34119.1 - 1.4e-24 86.6 0.0 2.8e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain IF4E PF01652.18 KER34119.1 - 3.6e-22 78.9 0.1 6e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Integrase_H2C2 PF17921.1 KER34119.1 - 7.6e-07 29.2 0.2 1.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KER34119.1 - 1.7e-06 27.7 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KER34119.1 - 0.14 12.4 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Nepo_coat_N PF03689.15 KER34120.1 - 0.066 13.2 0.3 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Nepovirus coat protein, N-terminal domain DUF454 PF04304.13 KER34120.1 - 5.2 7.1 5.5 6.2 6.9 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF454) DUF5313 PF17240.2 KER34121.1 - 0.041 14.3 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5313) HECT PF00632.25 KER34122.1 - 2.5e-90 303.1 0.2 4.7e-90 302.2 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Histone_H2A_C PF16211.5 KER34123.1 - 6.8e-13 48.1 0.6 1.4e-12 47.1 0.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KER34123.1 - 1.7e-08 34.9 0.2 4.6e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Core histone H2A/H2B/H3/H4 DUF5431 PF17496.2 KER34123.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5431) Ras PF00071.22 KER34124.1 - 1.1e-48 165.0 0.0 1.3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER34124.1 - 4.1e-19 69.0 0.0 2.1e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER34124.1 - 1.6e-08 34.2 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KER34124.1 - 1.4e-05 24.8 0.0 4.2e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER34124.1 - 0.00027 20.9 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KER34124.1 - 0.003 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.9 KER34124.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 KER34124.1 - 0.063 13.0 0.4 0.14 11.9 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KER34124.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_S21e PF01249.18 KER34126.1 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e ERAP1_C PF11838.8 KER34128.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Nod1 PF17114.5 KER34129.1 - 0.62 10.2 3.1 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 TPR_12 PF13424.6 KER34130.1 - 5.2e-15 55.5 10.6 6.9e-07 29.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KER34130.1 - 8.6e-11 41.3 1.5 0.00028 20.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KER34130.1 - 0.0017 18.4 0.4 0.62 10.4 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KER34130.1 - 0.046 13.6 8.7 0.7 9.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KER34130.1 - 0.054 13.6 8.2 0.55 10.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat GCS PF03074.16 KER34134.1 - 2.3e-154 514.2 0.0 3.1e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase WD40 PF00400.32 KER34135.1 - 8.2e-10 39.1 0.2 0.0027 18.5 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER34135.1 - 4.3e-07 30.2 0.0 0.0031 17.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 KER34135.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region AAA PF00004.29 KER34136.1 - 4.8e-39 133.8 0.0 1.2e-38 132.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KER34136.1 - 5.3e-08 32.5 0.1 1.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KER34136.1 - 1.1e-06 28.6 0.0 3.9e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 KER34136.1 - 8.3e-05 22.8 0.0 0.0025 17.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KER34136.1 - 0.0003 20.6 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KER34136.1 - 0.00042 20.3 0.1 0.0054 16.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FliG_N PF14842.6 KER34136.1 - 0.0043 17.6 0.5 0.04 14.5 0.1 2.6 3 0 0 3 3 3 1 FliG N-terminal domain TIP49 PF06068.13 KER34136.1 - 0.0051 16.1 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KER34136.1 - 0.0056 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KER34136.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KER34136.1 - 0.01 15.2 0.0 1.3 8.4 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 KER34136.1 - 0.013 15.9 1.1 0.15 12.4 0.6 3.0 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KER34136.1 - 0.013 15.2 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KER34136.1 - 0.02 15.2 0.9 0.27 11.5 0.0 3.1 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KER34136.1 - 0.024 14.4 0.0 0.86 9.3 0.0 2.8 1 1 0 1 1 1 0 Sigma-54 interaction domain MIT PF04212.18 KER34136.1 - 0.053 13.6 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_14 PF13173.6 KER34136.1 - 0.055 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KER34136.1 - 0.12 12.2 0.0 0.7 9.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 KER34136.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 KER34139.1 - 1.1e-47 163.0 0.2 1.3e-47 162.7 0.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 KER34139.1 - 0.00016 20.6 0.0 0.00022 20.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KER34140.1 - 2.6e-51 174.8 0.0 3.9e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34140.1 - 3.6e-07 30.5 3.1 7.4e-07 29.5 3.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 KER34141.1 - 1.4e-54 185.5 0.0 2.6e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34141.1 - 2.8e-09 37.3 2.2 4.5e-09 36.6 2.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER34141.1 - 0.0002 20.2 0.1 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 KER34142.1 - 3.7e-112 373.7 0.0 8.5e-55 186.2 0.0 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34142.1 - 4.8e-07 30.1 0.2 1.1e-06 29.0 0.2 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 KER34143.1 - 4.9e-72 242.6 0.0 1.4e-35 123.3 0.0 3.1 3 0 0 3 3 3 3 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34143.1 - 1.1e-14 54.6 8.9 1.1e-05 25.7 0.0 3.7 4 0 0 4 4 4 3 Cathepsin propeptide inhibitor domain (I29) Barwin PF00967.17 KER34143.1 - 0.03 14.1 0.6 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Barwin family PSI_PsaE PF02427.17 KER34143.1 - 0.052 13.2 0.0 20 4.9 0.0 3.4 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IV / PsaE Peptidase_C1 PF00112.23 KER34144.1 - 3.4e-127 422.9 0.2 3.6e-67 226.7 0.0 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34144.1 - 1.8e-17 63.5 5.7 1e-09 38.6 1.1 2.7 3 0 0 3 3 3 2 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER34144.1 - 8.8e-09 34.6 3.5 0.014 14.2 0.0 5.1 4 1 1 5 5 5 4 Peptidase C1-like family Peptidase_C1 PF00112.23 KER34145.1 - 7.8e-64 215.7 0.0 1e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 KER34145.1 - 5.6e-12 45.9 2.6 9.1e-12 45.2 2.6 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 KER34145.1 - 0.00032 19.6 0.1 0.068 11.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Ank_4 PF13637.6 KER34146.1 - 8.4e-20 70.9 10.4 3.1e-10 40.4 0.8 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KER34146.1 - 7.4e-16 58.5 1.1 1.5e-15 57.6 1.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER34146.1 - 1.7e-14 53.7 5.3 1.3e-08 35.0 0.7 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KER34146.1 - 2.8e-13 49.7 0.8 9.9e-06 25.8 0.4 3.5 4 0 0 4 4 4 2 Ankyrin repeat rve PF00665.26 KER34146.1 - 2e-11 44.1 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Ank_3 PF13606.6 KER34146.1 - 6.1e-11 41.6 1.9 7.3e-05 22.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat rve_3 PF13683.6 KER34146.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Aldolase_II PF00596.21 KER34148.1 - 1.7e-36 125.9 0.3 3.4e-36 124.9 0.3 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ras PF00071.22 KER34150.1 - 1.8e-61 206.5 0.3 2.4e-61 206.1 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KER34150.1 - 7.7e-35 119.7 0.2 1.3e-34 119.0 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KER34150.1 - 1.4e-15 57.2 0.1 1.8e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KER34150.1 - 1e-05 25.0 0.2 1.5e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KER34150.1 - 8e-05 22.3 0.2 0.00026 20.6 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KER34150.1 - 0.00016 21.6 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KER34150.1 - 0.0014 18.5 0.1 0.0043 16.9 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KER34150.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KER34150.1 - 0.013 14.9 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KER34150.1 - 0.028 14.0 0.1 0.26 10.8 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B RDD PF06271.12 KER34150.1 - 0.054 13.7 0.1 0.14 12.4 0.1 1.6 1 1 1 2 2 2 0 RDD family Septin PF00735.18 KER34150.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Septin Cpn60_TCP1 PF00118.24 KER34151.1 - 1.1e-102 344.2 6.1 1.3e-102 344.0 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.6 KER34151.1 - 0.0023 18.2 0.1 0.0036 17.6 0.1 1.2 1 0 0 1 1 1 1 PcfK-like protein bZIP_1 PF00170.21 KER34152.1 - 5.2e-08 32.9 13.3 9.9e-08 32.0 13.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KER34152.1 - 8.2e-06 25.8 14.6 1.3e-05 25.2 14.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KER34152.1 - 0.00047 20.6 15.2 0.001 19.5 15.2 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor HOOK PF05622.12 KER34152.1 - 0.013 13.7 1.8 0.019 13.2 1.8 1.1 1 0 0 1 1 1 0 HOOK protein KASH_CCD PF14662.6 KER34152.1 - 0.13 12.1 5.0 0.24 11.2 5.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KER34152.1 - 0.9 9.4 4.8 1.6 8.6 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator EGF PF00008.27 KER34155.1 - 0.11 12.9 6.5 0.11 12.9 4.0 2.1 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 KER34155.1 - 0.14 12.4 3.4 0.27 11.4 3.4 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 KER34155.1 - 5.1 7.6 6.0 9.7 6.7 6.0 1.5 1 0 0 1 1 1 0 EGF-like domain Thioredoxin_16 PF18569.1 KER34157.1 - 1.3e-18 66.9 0.8 2.4e-18 66.1 0.8 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DnaG_DnaB_bind PF08278.11 KER34157.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Glyco_hydro_15 PF00723.21 KER34158.1 - 2.7e-133 445.0 0.0 3.2e-133 444.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Creatinase_N_2 PF16189.5 KER34159.1 - 7.9e-41 139.8 0.0 1.4e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KER34159.1 - 2e-30 106.1 0.0 9e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.18 KER34159.1 - 5.4e-17 62.7 0.0 8.5e-13 49.1 0.0 2.9 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KER34159.1 - 6.3e-17 61.4 2.5 4.2e-16 58.8 1.0 2.6 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 LicD PF04991.13 KER34159.1 - 0.00012 22.3 0.0 0.076 13.1 0.0 2.6 2 1 1 3 3 3 2 LicD family DAO PF01266.24 KER34160.1 - 2.1e-58 198.6 0.0 2.6e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase RVT_1 PF00078.27 KER34160.1 - 3.4e-15 56.2 0.0 5.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thi4 PF01946.17 KER34160.1 - 0.0029 16.9 0.0 0.0068 15.7 0.0 1.6 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KER34160.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KER34160.1 - 0.017 13.7 0.0 0.034 12.7 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KER34160.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain SNF2_N PF00176.23 KER34161.1 - 8.5e-50 169.4 0.0 1.5e-26 93.0 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain ELMO_CED12 PF04727.13 KER34161.1 - 2.8e-36 125.3 2.5 5.5e-36 124.3 2.5 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Helicase_C PF00271.31 KER34161.1 - 1e-17 64.4 0.0 9.3e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KER34161.1 - 1.7e-08 34.0 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KER34161.1 - 1.9e-05 24.7 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tmemb_55A PF09788.9 KER34161.1 - 0.049 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A TrmB PF01978.19 KER34161.1 - 0.25 11.2 1.4 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fringe PF02434.16 KER34162.1 - 1.3e-06 28.0 0.5 1.2e-05 24.9 0.5 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 KER34162.1 - 7.1e-06 26.0 0.4 0.0013 18.6 0.3 2.3 1 1 1 2 2 2 2 Galactosyltransferase Birna_RdRp PF04197.12 KER34162.1 - 0.022 13.1 0.1 0.029 12.7 0.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Hydantoinase_B PF02538.14 KER34163.1 - 2.1e-209 696.3 0.1 2.7e-209 695.9 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KER34163.1 - 1.2e-78 264.3 0.1 6.9e-70 235.6 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KER34163.1 - 2.8e-23 82.5 0.0 3.5e-13 49.6 0.0 2.3 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Cation_efflux PF01545.21 KER34164.1 - 4e-46 157.3 10.2 4.9e-46 157.0 10.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KER34164.1 - 0.00029 20.9 0.6 0.00077 19.5 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF1282 PF06930.12 KER34164.1 - 0.74 9.6 11.4 0.6 9.9 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) SUR7 PF06687.12 KER34164.1 - 0.91 9.1 6.3 5.4 6.6 0.0 2.5 2 1 0 2 2 2 0 SUR7/PalI family DUF4231 PF14015.6 KER34164.1 - 1.2 9.7 4.2 19 5.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_M24 PF00557.24 KER34165.1 - 5.7e-08 32.7 0.0 8.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Sas10 PF09368.10 KER34166.1 - 9.5e-25 86.9 2.8 9.5e-25 86.9 2.8 1.9 2 0 0 2 2 2 1 Sas10 C-terminal domain 7TM_GPCR_Sri PF10327.9 KER34166.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri zf-U1 PF06220.12 KER34168.1 - 3.9e-07 29.7 1.6 7.2e-07 28.9 1.6 1.4 1 0 0 1 1 1 1 U1 zinc finger RRM_1 PF00076.22 KER34168.1 - 4.3e-07 29.6 0.1 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KER34168.1 - 0.0013 18.6 2.1 0.0066 16.3 0.2 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.8 KER34168.1 - 0.0037 17.5 1.8 0.013 15.8 1.8 2.0 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KER34168.1 - 0.1 13.1 1.0 0.29 11.7 1.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type WD40 PF00400.32 KER34169.1 - 3.2e-13 49.9 3.9 0.0032 18.3 0.0 8.6 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER34169.1 - 3.7e-05 23.9 0.0 21 5.5 0.0 5.7 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KER34169.1 - 0.0058 15.6 0.0 5.9 5.7 0.0 4.0 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 KER34170.1 - 6.9e-62 209.2 0.2 1.8e-61 207.8 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KER34170.1 - 6.7e-19 67.5 1.9 1.8e-09 37.4 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KER34170.1 - 1.1e-18 67.5 0.0 3.3e-18 66.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDH1_2_SANT_HL1 PF18375.1 KER34170.1 - 2.7e-16 60.0 1.2 6.6e-16 58.8 0.1 2.4 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 DUF4208 PF13907.6 KER34170.1 - 3.2e-15 56.3 2.3 1.4e-14 54.3 2.3 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 KER34170.1 - 0.00018 21.8 0.1 0.00018 21.8 0.1 3.4 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 Myb_DNA-binding PF00249.31 KER34170.1 - 0.019 15.1 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DCP1 PF06058.13 KER34171.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Dcp1-like decapping family Sof1 PF04158.14 KER34172.1 - 1.9e-25 89.0 7.5 3.3e-25 88.1 7.5 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KER34172.1 - 3.1e-16 59.5 4.9 1.6e-06 28.7 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat IBR PF01485.21 KER34172.1 - 7.9e-13 48.4 32.1 2.5e-08 34.0 3.0 4.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 KER34172.1 - 7.8e-08 32.6 0.1 1.5e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain ANAPC4_WD40 PF12894.7 KER34172.1 - 0.0002 21.6 0.0 4.1 7.8 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KER34172.1 - 0.00085 19.2 0.3 0.86 9.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_5 PF14634.6 KER34172.1 - 0.0086 16.0 9.7 0.0086 16.0 9.7 5.9 6 0 0 6 6 6 1 zinc-RING finger domain Cation_ATPase_C PF00689.21 KER34175.1 - 0.24 11.1 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SSF PF00474.17 KER34176.1 - 2.5e-127 425.1 24.7 5.6e-127 424.0 24.7 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family MCM PF00493.23 KER34178.1 - 7.7e-95 316.2 0.2 1.3e-94 315.5 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KER34178.1 - 1.8e-31 108.6 0.0 3.7e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KER34178.1 - 8.2e-23 80.6 0.6 1.9e-22 79.5 0.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KER34178.1 - 1.8e-08 34.9 0.1 5.1e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KER34178.1 - 1.9e-07 30.7 0.1 7.2e-07 28.8 0.0 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KER34178.1 - 0.0031 17.4 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KER34178.1 - 0.04 13.9 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KER34178.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DTHCT PF08070.11 KER34178.1 - 2.1 9.1 5.9 2.4 9.0 4.0 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF3504 PF12012.8 KER34179.1 - 1.3e-16 61.0 0.0 7.6e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Rad50_zn_hook PF04423.14 KER34179.1 - 0.022 14.6 0.5 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf_UBZ PF18439.1 KER34179.1 - 1.1 8.9 7.0 0.78 9.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 KER34181.1 - 2.2e-15 56.2 29.9 0.00077 19.8 0.2 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KER34181.1 - 6.2e-15 54.9 24.4 4.2e-07 30.1 0.3 5.0 4 0 0 4 4 4 3 Zinc-finger double domain zf_ZIC PF18366.1 KER34181.1 - 7.9e-15 54.7 1.0 6.5e-13 48.6 0.1 3.0 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 KER34181.1 - 6.6e-06 26.5 25.5 0.29 12.1 0.2 5.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KER34181.1 - 0.035 14.4 8.2 0.42 10.9 1.7 4.0 1 1 0 3 3 3 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KER34181.1 - 0.17 12.5 10.2 36 5.1 0.0 5.1 2 2 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KER34181.1 - 0.28 11.5 8.2 36 4.8 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KER34181.1 - 0.28 11.6 5.8 0.97 9.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DAZAP2 PF11029.8 KER34182.1 - 1.1e-09 39.3 24.8 1.9e-09 38.5 24.8 1.3 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) F5_F8_type_C PF00754.25 KER34183.1 - 0.00048 20.2 0.0 0.00057 20.0 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 KER34183.1 - 0.0018 18.3 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain Pkinase PF00069.25 KER34185.1 - 5.1e-43 147.3 0.1 8.8e-42 143.3 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER34185.1 - 3.4e-22 79.0 0.0 8.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KER34185.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KER34185.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KER34185.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KER34185.1 - 0.0043 15.9 0.0 0.0043 15.9 0.0 2.2 3 1 0 3 3 3 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KER34185.1 - 0.046 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3294 PF07957.11 KER34185.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Haspin_kinase PF12330.8 KER34185.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Cyt-b5 PF00173.28 KER34187.1 - 4e-07 30.1 0.1 8.8e-07 29.0 0.0 1.8 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain zf-B_box PF00643.24 KER34188.1 - 4.5e-10 39.5 17.5 5.1e-09 36.1 8.4 4.8 5 0 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 KER34188.1 - 2.7e-09 36.9 7.7 2.7e-09 36.9 7.7 3.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER34188.1 - 2.7e-06 27.1 12.3 2.7e-06 27.1 12.3 3.8 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KER34188.1 - 2.1e-05 24.2 7.0 2.1e-05 24.2 7.0 3.9 6 0 0 6 6 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KER34188.1 - 4.8e-05 23.6 9.8 4.8e-05 23.6 9.8 4.5 5 0 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KER34188.1 - 7.8e-05 22.5 11.0 7.8e-05 22.5 11.0 3.9 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KER34188.1 - 0.00015 21.5 8.7 0.00015 21.5 8.7 4.1 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KER34188.1 - 0.00058 19.7 8.4 0.00058 19.7 8.4 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 PhaP_Bmeg PF09602.10 KER34188.1 - 0.0013 18.7 0.6 0.0013 18.7 0.6 1.6 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) zf-C3HC4_4 PF15227.6 KER34188.1 - 0.0014 18.8 11.7 0.0014 18.8 11.7 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING SCAI PF12070.8 KER34188.1 - 0.019 13.9 0.2 0.027 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein SCAI Ferritin PF00210.24 KER34189.1 - 3.2e-38 130.9 3.6 3.7e-38 130.7 3.6 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KER34189.1 - 9.8e-06 26.0 3.7 1.5e-05 25.4 3.7 1.4 1 1 0 1 1 1 1 Rubrerythrin COQ7 PF03232.13 KER34189.1 - 0.058 13.2 1.3 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Homeodomain PF00046.29 KER34190.1 - 4.5e-20 71.3 6.9 4.5e-20 71.3 6.9 2.3 2 0 0 2 2 2 1 Homeodomain Peptidase_M64 PF09471.10 KER34190.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 THF_DHG_CYH_C PF02882.19 KER34191.1 - 1.2e-48 164.5 0.0 8.8e-48 161.6 0.0 2.2 2 1 1 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KER34191.1 - 2.6e-25 88.9 0.0 4.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KER34191.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Cadherin PF00028.17 KER34194.1 - 2.2e-46 156.2 1.0 9.7e-10 38.8 0.0 9.0 7 3 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 KER34194.1 - 4.7e-05 23.4 10.3 0.17 11.9 0.0 5.4 5 0 0 5 5 5 3 Cadherin-like Cadherin_2 PF08266.12 KER34194.1 - 0.0016 18.3 0.1 0.23 11.3 0.0 4.2 7 0 0 7 7 7 1 Cadherin-like ASRT PF07100.11 KER34194.1 - 0.029 14.4 0.7 4.3 7.4 0.1 2.8 2 0 0 2 2 2 0 Anabaena sensory rhodopsin transducer Sec15 PF04091.12 KER34195.1 - 4.4e-46 157.7 0.0 3.3e-45 154.9 0.0 2.2 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DrsE_2 PF13686.6 KER34195.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family DUF3137 PF11335.8 KER34195.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) WD40 PF00400.32 KER34196.1 - 1.4e-08 35.2 8.7 0.02 15.8 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KER34196.1 - 0.00024 21.3 0.3 0.27 11.5 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KER34196.1 - 0.0039 17.2 0.0 0.13 12.3 0.1 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 KER34196.1 - 0.0086 16.0 0.0 1.2 9.0 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A EGF PF00008.27 KER34198.1 - 8e-10 38.8 31.4 1.3e-05 25.3 2.4 4.1 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.7 KER34198.1 - 3e-05 24.5 29.9 0.0014 19.2 4.6 4.5 4 0 0 4 4 4 3 Human growth factor-like EGF UPF0560 PF10577.9 KER34198.1 - 0.0033 16.0 0.1 0.0043 15.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 EGF_2 PF07974.13 KER34198.1 - 0.034 14.5 3.1 0.034 14.5 3.1 4.0 4 0 0 4 4 4 0 EGF-like domain GDE_N_bis PF14742.6 KER34198.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes F5_F8_type_C PF00754.25 KER34199.1 - 5.3e-12 46.0 0.0 5.3e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 F5/8 type C domain Cadherin_C_2 PF16492.5 KER34199.1 - 0.12 13.1 0.1 0.73 10.6 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal ToxB_N PF18224.1 KER34201.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 ToxB N-terminal domain DUF702 PF05142.12 KER34201.1 - 0.32 11.5 6.1 0.41 11.1 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF702) CBM53 PF16760.5 KER34204.1 - 7.1e-06 26.5 0.1 1.9e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_21 PF03370.13 KER34204.1 - 0.00048 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) Glyco_transf_24 PF18404.1 KER34205.1 - 5.3e-148 491.6 0.4 8.1e-148 491.0 0.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KER34205.1 - 5.9e-59 200.1 0.0 4.9e-58 197.1 0.0 2.6 5 0 0 5 5 5 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KER34205.1 - 1.8e-33 115.4 0.1 4.8e-33 113.9 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KER34205.1 - 1.4e-31 109.8 0.1 3.4e-31 108.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KER34205.1 - 2.7e-31 107.9 0.0 1.7e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 KER34205.1 - 3.1e-28 99.2 0.0 8e-24 84.8 0.0 4.7 3 2 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KER34205.1 - 0.00015 21.4 0.1 0.00037 20.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 ArfGap PF01412.18 KER34206.1 - 4.7e-25 87.9 0.2 7.7e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.7 KER34206.1 - 0.16 12.1 1.3 1.9 8.6 0.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KER34206.1 - 0.19 12.2 0.3 0.36 11.3 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c3 Ets PF00178.22 KER34207.1 - 1.6e-18 67.0 0.1 3.4e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 Ets-domain Ax_dynein_light PF10211.9 KER34208.1 - 3.8e-45 154.1 3.3 4.2e-45 154.0 3.3 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain DUF4201 PF13870.6 KER34208.1 - 0.0027 17.5 2.9 0.0046 16.7 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF16 PF01519.16 KER34208.1 - 0.0062 17.0 0.8 0.0097 16.4 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF16 PLC-beta_C PF08703.10 KER34208.1 - 0.0064 16.5 2.5 0.0064 16.5 2.5 1.7 2 0 0 2 2 2 1 PLC-beta C terminal ZapB PF06005.12 KER34208.1 - 0.021 15.3 2.4 0.041 14.3 2.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 KER34208.1 - 0.024 14.9 2.3 0.024 14.9 2.3 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 KER34208.1 - 0.029 14.6 1.6 0.051 13.8 1.6 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.21 KER34208.1 - 0.17 12.0 4.4 0.2 11.8 3.0 1.7 1 1 0 1 1 1 0 bZIP transcription factor MIP-T3_C PF17749.1 KER34208.1 - 0.27 11.2 5.8 2.1 8.3 6.8 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region JIP_LZII PF16471.5 KER34208.1 - 0.27 11.4 4.2 0.16 12.2 2.2 1.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CUT PF02376.15 KER34210.1 - 1.5e-28 98.7 0.5 7.6e-15 54.8 0.1 2.9 2 0 0 2 2 2 2 CUT domain Homeodomain PF00046.29 KER34210.1 - 1e-14 54.1 0.9 2.4e-14 52.9 0.2 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KER34210.1 - 0.00048 20.0 0.2 0.0017 18.2 0.2 2.1 1 0 0 1 1 1 1 Homeobox KN domain HNF-1_N PF04814.13 KER34210.1 - 0.46 11.1 0.0 0.46 11.1 0.0 4.6 3 1 1 4 4 4 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus WWE PF02825.20 KER34214.1 - 2.1e-17 63.5 0.2 3.9e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 WWE domain Ank_5 PF13857.6 KER34215.1 - 4.8e-06 26.7 0.0 1.4e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KER34215.1 - 8.7e-06 26.0 0.1 9.2e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KER34215.1 - 0.00011 22.7 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KER34215.1 - 0.017 15.7 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RVT_1 PF00078.27 KER34218.1 - 3.9e-44 150.8 0.0 9.7e-44 149.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VHL PF01847.16 KER34218.1 - 3.7e-10 39.6 0.1 1.1e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 VHL beta domain AAA_18 PF13238.6 KER34219.1 - 5.8e-12 46.3 0.0 6.6e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KER34219.1 - 5.8e-06 26.8 0.0 6.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KER34219.1 - 0.00039 20.9 0.0 0.00039 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KER34219.1 - 0.00077 19.5 0.0 0.00077 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KER34219.1 - 0.0014 19.0 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KER34219.1 - 0.0023 18.1 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KER34219.1 - 0.0032 17.7 0.0 0.0034 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KER34219.1 - 0.0045 16.9 0.2 0.0061 16.5 0.1 1.3 1 1 0 1 1 1 1 NTPase DUF2075 PF09848.9 KER34219.1 - 0.0055 16.0 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KER34219.1 - 0.0057 16.4 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KER34219.1 - 0.006 16.9 0.1 0.0081 16.4 0.1 1.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KER34219.1 - 0.008 15.4 0.0 0.0088 15.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KER34219.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KER34219.1 - 0.021 14.1 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KER34219.1 - 0.023 15.1 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KER34219.1 - 0.028 14.2 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KER34219.1 - 0.029 13.8 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KER34219.1 - 0.034 14.5 0.5 0.044 14.1 0.3 1.3 1 1 0 1 1 1 0 AAA domain YafQ_toxin PF15738.5 KER34219.1 - 0.046 14.0 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ AAA_24 PF13479.6 KER34219.1 - 0.063 13.0 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KER34219.1 - 0.085 12.2 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 KER34219.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KER34219.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KER34219.1 - 0.11 11.8 0.6 0.18 11.1 0.2 1.5 1 1 1 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 KER34219.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KER34219.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 KER34219.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family NACHT PF05729.12 KER34219.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 KER34219.1 - 0.2 11.1 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KER34219.1 - 0.41 10.3 1.4 0.69 9.6 0.7 1.7 1 1 1 2 2 2 0 AAA domain Collagen PF01391.18 KER34220.1 - 8.7e-117 380.9 430.7 3.3e-10 39.6 28.3 14.8 2 2 9 11 11 11 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 KER34220.1 - 4.5e-07 29.4 0.0 5.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain SOAR PF16533.5 KER34221.1 - 8.1e-25 86.7 1.1 1.8e-24 85.6 1.1 1.6 1 0 0 1 1 1 1 STIM1 Orai1-activating region SAM_1 PF00536.30 KER34221.1 - 5.5e-08 33.1 0.1 1.1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KER34221.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MgtE PF01769.16 KER34222.1 - 5.1e-15 56.0 22.9 8.4e-08 32.6 10.2 4.4 4 1 0 4 4 4 3 Divalent cation transporter Fmp27_GFWDK PF10347.9 KER34225.1 - 0.058 13.5 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RXT2_N PF08595.11 KER34226.1 - 0.065 13.3 1.4 0.1 12.6 1.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 KER34226.1 - 0.15 11.7 12.1 0.19 11.5 12.1 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KER34226.1 - 0.24 10.7 8.5 0.33 10.2 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KER34226.1 - 1.8 6.5 9.1 2.5 6.1 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KER34226.1 - 2.6 8.5 15.8 4.7 7.7 15.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain K_channel_TID PF07941.11 KER34230.1 - 0.34 11.4 4.9 1.6 9.2 5.1 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Spond_N PF06468.13 KER34233.1 - 4.9e-40 137.7 0.0 8.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Spondin_N Kunitz_BPTI PF00014.23 KER34233.1 - 6.6e-15 55.1 17.6 6.5e-11 42.3 4.1 3.6 3 1 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Ig_3 PF13927.6 KER34234.1 - 6.9e-08 33.0 0.2 0.045 14.4 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 KER34234.1 - 7.1e-07 29.2 0.0 0.0041 17.1 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 KER34234.1 - 1e-06 28.8 0.2 0.18 12.0 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 KER34234.1 - 2.5e-06 27.6 0.0 0.01 16.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.6 KER34234.1 - 0.00012 22.4 1.1 1.6 9.2 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain Ig_6 PF18452.1 KER34234.1 - 0.016 14.7 0.1 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin domain Tim44 PF04280.15 KER34235.1 - 1.6e-22 80.2 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain UQ_con PF00179.26 KER34236.1 - 1.2e-50 170.8 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KER34236.1 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KER34236.1 - 0.022 15.0 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain PDZ PF00595.24 KER34238.1 - 9.5e-18 64.3 0.0 1.9e-09 37.8 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 KER34238.1 - 3.2e-12 46.1 0.5 2.7e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KER34238.1 - 5e-11 42.8 0.0 1.9e-08 34.5 0.1 3.2 3 0 0 3 3 3 1 PDZ domain PDZ_3 PF17815.1 KER34238.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Sec2p PF06428.11 KER34239.1 - 0.037 14.0 8.9 0.052 13.5 8.0 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p SHE3 PF17078.5 KER34239.1 - 0.057 13.1 9.7 0.097 12.4 9.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF2968 PF11180.8 KER34239.1 - 0.063 12.9 4.0 0.1 12.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF812 PF05667.11 KER34239.1 - 0.097 11.5 8.3 0.14 11.0 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2400 PF09674.10 KER34239.1 - 0.14 12.1 1.5 0.23 11.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DASH_Hsk3 PF08227.11 KER34239.1 - 0.17 12.3 1.6 0.46 10.9 1.6 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF1664 PF07889.12 KER34239.1 - 0.22 11.5 4.7 0.24 11.5 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 KER34239.1 - 0.25 11.1 3.6 0.48 10.2 3.6 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin-6_N PF09177.11 KER34239.1 - 0.33 11.5 3.7 0.81 10.3 3.7 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal VPS38 PF17649.1 KER34239.1 - 0.37 9.6 4.9 0.57 9.0 4.9 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Jnk-SapK_ap_N PF09744.9 KER34239.1 - 0.38 11.0 13.7 0.7 10.1 13.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FmiP_Thoc5 PF09766.9 KER34239.1 - 0.7 9.1 9.1 1.3 8.3 9.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 KLRAQ PF10205.9 KER34239.1 - 2.2 8.6 8.7 2.6 8.3 5.4 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Iron_permease PF04120.12 KER34239.1 - 4.4 7.1 6.4 2.3 8.0 2.6 2.2 1 1 1 2 2 2 0 Low affinity iron permease TMPIT PF07851.13 KER34239.1 - 4.5 6.4 5.8 7.5 5.7 5.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 KER34239.1 - 5 5.6 4.5 8 4.9 4.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A MucB_RseB PF03888.14 KER34240.1 - 0.054 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Dynactin_p62 PF05502.13 KER34242.1 - 0.25 10.1 0.8 0.28 9.9 0.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family Arf PF00025.21 KER34243.1 - 1.4e-39 135.4 0.2 1.6e-37 128.6 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KER34243.1 - 1.8e-13 50.4 0.0 6.7e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KER34243.1 - 8.6e-12 45.3 0.1 2.7e-11 43.7 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KER34243.1 - 1.5e-08 34.2 0.0 6.9e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KER34243.1 - 2.5e-05 23.7 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KER34243.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KER34243.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TRA-1_regulated PF02343.16 KER34243.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 SNF2_N PF00176.23 KER34244.1 - 1.4e-44 152.3 0.0 3.6e-43 147.6 0.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KER34244.1 - 1.7e-15 57.3 0.0 6.9e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TPR_2 PF07719.17 KER34244.1 - 4.4e-07 29.5 0.2 0.24 11.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KER34244.1 - 1.1e-05 25.6 0.4 2.8 8.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KER34244.1 - 0.00036 21.0 0.0 0.44 11.1 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KER34244.1 - 0.0004 21.0 0.1 3.6 8.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ResIII PF04851.15 KER34244.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_8 PF13181.6 KER34244.1 - 0.0014 18.7 0.1 1.2 9.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KER34244.1 - 0.0015 18.8 0.0 0.79 10.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KER34244.1 - 0.0019 18.7 0.4 5.8 7.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KER34244.1 - 0.0055 16.5 0.1 0.56 10.1 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KER34244.1 - 0.062 13.8 0.1 11 6.5 0.0 2.5 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_16 PF13432.6 KER34244.1 - 0.088 13.5 0.4 52 4.6 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat PDZ PF00595.24 KER34245.1 - 2.2e-07 31.1 0.0 6.6e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KER34245.1 - 0.0032 17.3 0.0 0.0076 16.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CEP63 PF17045.5 KER34247.1 - 2e-06 27.9 40.9 2e-06 27.9 40.9 3.6 3 0 0 3 3 3 1 Centrosomal protein of 63 kDa Baculo_LEF5 PF04838.12 KER34247.1 - 0.05 13.7 3.0 0.13 12.3 2.8 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 Hemagglutinin PF00509.18 KER34247.1 - 0.57 8.5 7.2 0.03 12.7 0.7 2.0 2 0 0 2 2 2 0 Haemagglutinin DUF639 PF04842.12 KER34247.1 - 4.6 6.6 9.2 1.7 8.0 0.2 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF639) Med13_C PF06333.12 KER34248.1 - 8e-68 229.1 4.6 2.6e-39 135.4 0.0 3.6 4 1 0 4 4 4 2 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KER34248.1 - 1.4e-36 126.5 0.0 2.6e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KER34248.1 - 2.7e-15 56.8 0.0 1.1e-14 54.9 0.1 2.0 2 0 0 2 2 2 1 MID domain of medPIWI LSM PF01423.22 KER34249.1 - 3e-20 71.7 0.1 4.5e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain RVT_1 PF00078.27 KER34249.1 - 1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH2 PF00017.24 KER34250.1 - 8.4e-11 41.8 0.0 8.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 KER34250.1 - 2.9e-07 30.9 0.0 1.1e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KER34250.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SatRNA_48 PF17485.2 KER34250.1 - 0.03 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein RVT_1 PF00078.27 KER34252.1 - 3e-08 33.5 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ToxB_N PF18224.1 KER34253.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 ToxB N-terminal domain Ion_trans PF00520.31 KER34254.1 - 1.7e-39 135.6 12.7 2.2e-39 135.2 12.7 1.1 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KER34254.1 - 3.2e-23 81.9 0.0 8.2e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 KER34254.1 - 1.9e-12 47.0 6.4 1.9e-12 47.0 6.4 2.9 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 KER34254.1 - 0.00018 21.6 0.0 0.00098 19.2 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain FGFR3_TM PF18123.1 KER34254.1 - 0.14 11.7 6.8 0.75 9.4 0.1 2.8 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain PKD_channel PF08016.12 KER34254.1 - 0.17 10.5 14.1 0.5 9.0 14.1 1.8 1 1 0 1 1 1 0 Polycystin cation channel DUF5326 PF17260.2 KER34254.1 - 2 8.6 5.4 0.4 10.8 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Gal-bind_lectin PF00337.22 KER34255.1 - 4.5e-14 52.1 0.0 3e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Galactoside-binding lectin SNAP-25 PF00835.19 KER34256.1 - 5.5e-11 42.6 1.2 1.2e-10 41.5 1.2 1.7 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.8 KER34256.1 - 0.00029 21.1 5.6 0.008 16.4 0.4 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DASH_Duo1 PF08651.10 KER34256.1 - 0.0028 17.4 2.8 0.46 10.3 0.0 3.2 3 1 1 4 4 4 2 DASH complex subunit Duo1 DUF16 PF01519.16 KER34256.1 - 0.0036 17.8 7.6 0.18 12.3 0.4 2.5 2 1 0 2 2 2 2 Protein of unknown function DUF16 DUF5089 PF17002.5 KER34256.1 - 0.0058 16.5 8.9 0.082 12.8 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) DUF948 PF06103.11 KER34256.1 - 0.57 10.5 4.9 4.6 7.6 0.4 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 KER34256.1 - 0.69 9.6 7.3 0.48 10.1 0.4 2.7 2 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 KER34256.1 - 1.8 8.6 9.7 1.2 9.1 0.2 2.9 2 1 1 3 3 3 0 Laminin Domain II DivIC PF04977.15 KER34256.1 - 2.6 7.9 7.6 3.4 7.5 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator BCDHK_Adom3 PF10436.9 KER34258.1 - 2.4e-35 121.8 0.0 3.2e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KER34258.1 - 4.2e-06 27.2 0.0 1.7e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KER34258.1 - 0.0026 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PhoU_div PF01865.16 KER34258.1 - 0.038 13.3 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 TFIIS_C PF01096.18 KER34260.1 - 6.3e-19 67.6 4.6 6.3e-19 67.6 4.6 2.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KER34260.1 - 0.0024 17.8 2.5 0.0024 17.8 2.5 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 KER34260.1 - 0.0058 16.5 6.7 0.48 10.4 0.1 3.1 3 0 0 3 3 3 2 zinc-ribbon domain DUF2072 PF09845.9 KER34260.1 - 0.02 15.1 0.7 0.042 14.1 0.7 1.6 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-Dof PF02701.15 KER34260.1 - 0.023 14.8 3.5 0.023 14.8 3.5 2.1 2 0 0 2 2 2 0 Dof domain, zinc finger TF_Zn_Ribbon PF08271.12 KER34260.1 - 0.14 11.7 0.4 0.14 11.7 0.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 KER34260.1 - 0.86 10.0 9.5 2.9 8.3 1.3 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 KER34260.1 - 1.2 8.9 8.2 3.6 7.4 1.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Nop10p PF04135.12 KER34260.1 - 3.2 7.9 6.7 49 4.1 0.3 3.5 3 1 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family zf-C4_Topoisom PF01396.19 KER34260.1 - 5.7 6.8 10.8 2.8 7.8 0.5 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Glyco_hydro_63 PF03200.16 KER34262.1 - 5.7e-172 572.9 0.0 1.1e-171 571.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KER34262.1 - 3.8e-39 135.1 0.1 7.2e-39 134.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain UAA PF08449.11 KER34263.1 - 1.2e-50 172.5 24.8 1.4e-50 172.3 24.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KER34263.1 - 2.8e-09 37.3 31.5 7e-08 32.7 13.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 KER34263.1 - 1.2e-05 24.8 18.4 3.1e-05 23.5 18.4 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 KER34263.1 - 0.001 18.3 3.4 0.021 14.0 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TMEM234 PF10639.9 KER34263.1 - 0.014 15.4 4.6 0.014 15.4 4.6 2.7 2 1 1 3 3 3 0 Putative transmembrane family 234 GCM PF03615.15 KER34265.1 - 9.1e-61 203.8 4.4 1.8e-60 202.9 4.4 1.5 1 0 0 1 1 1 1 GCM motif protein Haem_bd PF14376.6 KER34265.1 - 0.08 12.9 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 Haem-binding domain Pkinase PF00069.25 KER34266.1 - 2.7e-47 161.3 0.0 4.6e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KER34266.1 - 5.2e-16 58.7 0.0 2e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase HipN PF18253.1 KER34266.1 - 0.15 11.8 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain P2X_receptor PF00864.19 KER34269.1 - 2.6e-82 276.8 0.0 1.4e-53 182.3 0.1 2.2 2 0 0 2 2 2 2 ATP P2X receptor P2X_receptor PF00864.19 KER34270.1 - 1.5e-86 290.8 0.4 2.8e-50 171.4 0.1 2.1 2 0 0 2 2 2 2 ATP P2X receptor PRMT5_TIM PF17285.2 KER34270.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 PRMT5 TIM barrel domain Filamin PF00630.19 KER34271.1 - 1.4e-06 29.1 0.0 2.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_2 PF13639.6 KER34271.1 - 1.6e-06 28.3 10.5 1.6e-06 28.3 10.5 3.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KER34271.1 - 2.9e-05 23.8 8.2 2.9e-05 23.8 8.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KER34271.1 - 3e-05 23.9 10.5 3e-05 23.9 10.5 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-B_box PF00643.24 KER34271.1 - 4.2e-05 23.6 3.8 4.2e-05 23.6 3.8 3.4 3 1 1 4 4 3 1 B-box zinc finger Prok-RING_4 PF14447.6 KER34271.1 - 4.5e-05 23.2 8.0 4.5e-05 23.2 8.0 2.8 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KER34271.1 - 0.00035 20.5 5.5 0.00035 20.5 5.5 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KER34271.1 - 0.001 18.9 10.6 0.001 18.9 10.6 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KER34271.1 - 0.0017 18.1 8.4 0.0017 18.1 8.4 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain NHL PF01436.21 KER34271.1 - 0.0019 18.1 0.0 16 5.7 0.0 4.6 4 0 0 4 4 4 0 NHL repeat zf-C3HC4_4 PF15227.6 KER34271.1 - 0.002 18.3 2.8 0.002 18.3 2.8 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KER34271.1 - 0.0084 15.9 10.7 0.0084 15.9 10.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TORC_N PF12884.7 KER34271.1 - 0.048 14.5 0.0 0.17 12.7 0.0 1.9 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus zf-ANAPC11 PF12861.7 KER34271.1 - 2.1 8.5 11.8 0.036 14.1 3.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 KER34271.1 - 6.7 6.7 13.2 0.34 10.8 1.6 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NCBP3 PF10309.9 KER34273.1 - 9.7e-06 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Ferritin PF00210.24 KER34274.1 - 6.2e-34 117.0 0.0 7.4e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KER34274.1 - 9.4e-07 29.3 0.3 1.4e-06 28.7 0.3 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 KER34274.1 - 0.011 16.1 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) COQ7 PF03232.13 KER34274.1 - 0.067 13.0 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Homeobox_KN PF05920.11 KER34275.1 - 2.8e-11 43.1 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KER34275.1 - 3e-06 27.0 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain p450 PF00067.22 KER34276.1 - 2.4e-33 115.6 1.5 1.1e-20 73.8 0.3 3.1 2 1 1 3 3 3 3 Cytochrome P450 CobT PF06213.12 KER34277.1 - 0.0042 16.5 30.3 0.0044 16.4 30.3 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT NARP1 PF12569.8 KER34277.1 - 0.018 14.0 20.4 0.02 13.8 20.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2076 PF09849.9 KER34277.1 - 0.024 14.7 39.4 0.032 14.3 39.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Connexin PF00029.19 KER34277.1 - 0.025 14.4 18.4 0.028 14.2 18.4 1.1 1 0 0 1 1 1 0 Connexin CCDC53 PF10152.9 KER34277.1 - 0.025 15.0 22.8 0.029 14.8 22.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex YABBY PF04690.13 KER34277.1 - 0.026 15.1 19.2 0.03 14.9 19.2 1.1 1 0 0 1 1 1 0 YABBY protein Pex14_N PF04695.13 KER34277.1 - 0.027 15.2 35.8 0.032 14.9 35.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 KER34277.1 - 0.028 13.9 25.5 0.033 13.6 25.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 KER34277.1 - 0.032 12.3 21.1 0.034 12.2 21.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 KER34277.1 - 0.036 13.0 17.5 0.042 12.8 17.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2072 PF09845.9 KER34277.1 - 0.042 14.1 17.6 0.057 13.7 17.6 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein RR_TM4-6 PF06459.12 KER34277.1 - 0.042 13.7 23.1 0.042 13.7 23.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2776 PF10951.8 KER34277.1 - 0.046 13.0 0.6 0.052 12.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2776) CLN3 PF02487.17 KER34277.1 - 0.052 12.6 18.1 0.059 12.4 18.1 1.1 1 0 0 1 1 1 0 CLN3 protein TCP PF03634.13 KER34277.1 - 0.056 14.0 23.5 0.067 13.7 23.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor PAT1 PF09770.9 KER34277.1 - 0.07 11.4 37.7 0.068 11.4 37.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 KER34277.1 - 0.078 11.7 28.8 0.088 11.6 28.8 1.1 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 KER34277.1 - 0.079 13.1 24.6 0.093 12.9 24.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF5523 PF17661.1 KER34277.1 - 0.084 12.5 21.0 0.092 12.4 21.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) V_ATPase_I PF01496.19 KER34277.1 - 0.11 10.4 25.4 0.11 10.4 25.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 KER34277.1 - 0.13 11.2 26.1 0.15 11.1 26.1 1.1 1 0 0 1 1 1 0 Paf1 Rtf2 PF04641.12 KER34277.1 - 0.14 11.5 24.8 0.17 11.2 24.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SID-1_RNA_chan PF13965.6 KER34277.1 - 0.15 10.5 12.2 0.16 10.4 12.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF5308 PF17233.2 KER34277.1 - 0.17 12.1 17.8 0.2 11.9 17.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SARAF PF06682.12 KER34277.1 - 0.18 11.4 20.8 0.2 11.2 20.8 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Velvet PF11754.8 KER34277.1 - 0.18 11.7 22.7 0.19 11.6 22.7 1.1 1 0 0 1 1 1 0 Velvet factor EOS1 PF12326.8 KER34277.1 - 0.23 11.4 14.6 0.31 11.0 14.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein PTPRCAP PF15713.5 KER34277.1 - 0.25 11.6 23.6 0.29 11.4 23.6 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PIP5K PF01504.18 KER34277.1 - 0.25 10.5 20.1 0.3 10.3 20.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Pannexin_like PF12534.8 KER34277.1 - 0.29 10.2 17.4 0.33 10.0 17.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CPSF100_C PF13299.6 KER34277.1 - 0.3 11.3 19.5 0.41 10.8 19.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MMM1 PF10296.9 KER34277.1 - 0.3 10.1 15.7 0.35 9.9 15.7 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Endostatin PF06482.11 KER34277.1 - 0.3 10.5 22.1 0.31 10.5 22.1 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 KER34277.1 - 0.31 10.0 24.8 0.32 10.0 24.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Band_3_cyto PF07565.13 KER34277.1 - 0.34 10.7 23.4 0.43 10.4 23.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.17 KER34277.1 - 0.35 11.0 23.5 0.44 10.7 23.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF3295 PF11702.8 KER34277.1 - 0.37 10.1 22.8 0.4 10.0 22.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CDC45 PF02724.14 KER34277.1 - 0.38 9.0 21.4 0.43 8.8 21.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Ctr PF04145.15 KER34277.1 - 0.54 10.9 12.9 0.69 10.5 12.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Serinc PF03348.15 KER34277.1 - 0.55 9.1 16.5 0.58 9.0 16.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 KER34277.1 - 0.57 8.9 10.6 0.67 8.6 10.6 1.1 1 0 0 1 1 1 0 Ureide permease XRN_M PF17846.1 KER34277.1 - 0.71 8.8 19.4 0.8 8.6 19.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Baculo_PP31 PF05311.11 KER34277.1 - 0.77 9.2 21.3 0.98 8.8 21.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CSG2 PF16965.5 KER34277.1 - 0.8 8.6 14.1 0.96 8.3 14.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4746 PF15928.5 KER34277.1 - 0.82 9.0 17.5 0.98 8.8 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 KER34277.1 - 0.89 9.1 28.1 0.97 8.9 28.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPP4R2 PF09184.11 KER34277.1 - 0.89 9.1 14.9 0.92 9.0 14.9 1.1 1 0 0 1 1 1 0 PPP4R2 ALMT PF11744.8 KER34277.1 - 0.95 8.2 22.7 1.1 8.0 22.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 KER34277.1 - 1 9.4 19.9 1.1 9.3 19.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GPCR_chapero_1 PF11904.8 KER34277.1 - 1 8.7 16.7 1.2 8.5 16.7 1.1 1 0 0 1 1 1 0 GPCR-chaperone CBP_BcsG PF11658.8 KER34277.1 - 1.1 7.6 19.4 1.3 7.4 19.4 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG BORG_CEP PF14957.6 KER34277.1 - 1.3 10.2 16.8 1.5 10.0 16.8 1.2 1 0 0 1 1 1 0 Cdc42 effector O-antigen_lig PF13425.6 KER34277.1 - 1.5 7.5 16.0 1.8 7.2 16.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF908 PF06012.12 KER34277.1 - 1.7 8.0 20.7 1.8 7.9 20.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Plasmodium_Vir PF05795.11 KER34277.1 - 1.7 8.0 17.7 1.9 7.8 17.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2126 PF09899.9 KER34277.1 - 1.9 6.5 18.4 2 6.4 18.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2464 PF10240.9 KER34277.1 - 1.9 8.0 16.4 2.1 7.8 16.4 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Hid1 PF12722.7 KER34277.1 - 2 6.4 24.1 2 6.4 24.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 KER34277.1 - 2.5 7.4 28.8 3.4 7.0 28.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4758 PF15950.5 KER34277.1 - 2.6 8.4 6.7 3.5 8.0 6.7 1.3 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF4228 PF14009.6 KER34277.1 - 2.8 8.3 13.8 3.2 8.1 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TMEM144 PF07857.12 KER34277.1 - 3.1 6.7 7.9 4.3 6.2 7.9 1.3 1 1 0 1 1 1 0 Transmembrane family, TMEM144 of transporters HCO3_cotransp PF00955.21 KER34277.1 - 3.1 6.5 12.8 3.2 6.5 12.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family Membralin PF09746.9 KER34277.1 - 3.3 6.7 17.5 3.3 6.6 17.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Pal1 PF08316.11 KER34277.1 - 3.3 8.5 14.8 4.7 8.0 14.8 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Peptidase_S15 PF02129.18 KER34277.1 - 3.9 7.0 18.5 4.8 6.7 18.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) STAC2_u1 PF16664.5 KER34277.1 - 4.4 7.8 19.4 5.9 7.4 19.4 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 TT_ORF1 PF02956.14 KER34277.1 - 4.5 5.8 23.1 4.7 5.8 23.1 1.0 1 0 0 1 1 1 0 TT viral orf 1 Spore_coat_CotO PF14153.6 KER34277.1 - 4.7 7.1 34.0 5.5 6.9 34.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PepSY_TM PF03929.16 KER34277.1 - 4.7 6.8 14.6 7 6.2 14.6 1.3 1 0 0 1 1 1 0 PepSY-associated TM region BNR_3 PF13859.6 KER34277.1 - 5 6.3 12.9 7 5.8 12.9 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF4638 PF15472.6 KER34277.1 - 5 6.8 23.8 5.4 6.7 23.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Folliculin PF11704.8 KER34277.1 - 5.2 6.9 21.3 6.2 6.7 21.3 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport F-protein PF00469.20 KER34277.1 - 5.4 6.6 19.9 6.2 6.4 19.9 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef NPR3 PF03666.13 KER34277.1 - 5.5 5.7 26.6 6.6 5.4 26.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 KER34277.1 - 6.7 5.4 17.0 6.8 5.4 17.0 1.1 1 0 0 1 1 1 0 Otopetrin PBP1_TM PF14812.6 KER34277.1 - 6.8 7.1 15.0 9.4 6.7 15.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1682 PF07946.14 KER34277.1 - 7.7 5.6 24.2 8.5 5.5 24.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PPL5 PF18168.1 KER34277.1 - 7.9 5.7 20.9 10 5.3 20.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Phage_GPO PF05929.11 KER34277.1 - 8.8 5.9 24.5 9.8 5.7 24.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Peptidase_M14 PF00246.24 KER34278.1 - 1.6e-73 248.1 0.0 2e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 KER34278.1 - 6.4e-12 45.7 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF4404 PF14357.6 KER34278.1 - 0.7 10.6 2.1 0.59 10.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) LRR_6 PF13516.6 KER34279.1 - 1.2e-05 25.0 20.4 0.091 12.9 0.9 6.4 8 0 0 8 8 8 3 Leucine Rich repeat Armet PF10208.9 KER34279.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding LRR_4 PF12799.7 KER34279.1 - 5.5 7.5 11.6 26 5.4 0.1 5.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) MaoC_dehydratas PF01575.19 KER34281.1 - 1.9e-18 66.2 0.0 2.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 KER34281.1 - 2.4e-05 24.6 0.4 5.7e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Thioesterase superfamily MaoC_dehydrat_N PF13452.6 KER34281.1 - 3.4e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase DUF3636 PF12331.8 KER34283.1 - 0.021 14.7 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) 7tm_1 PF00001.21 KER34284.1 - 4.4e-21 75.4 12.8 5.8e-21 75.0 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 KER34284.1 - 3.4e-13 49.6 27.5 1.3e-06 28.0 18.1 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2633 PF11119.8 KER34284.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) TMEM154 PF15102.6 KER34284.1 - 0.1 12.5 0.0 0.66 9.9 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family CPBP PF02517.16 KER34284.1 - 0.11 12.9 7.2 0.11 12.9 0.0 2.9 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease Claudin_2 PF13903.6 KER34284.1 - 6.5 6.5 15.4 0.089 12.5 4.2 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction E1-E2_ATPase PF00122.20 KER34285.1 - 4.9e-22 78.3 0.0 1.2e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KER34285.1 - 1e-13 52.1 0.0 8.7e-08 32.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KER34285.1 - 0.00051 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) TMPIT PF07851.13 KER34286.1 - 3.2e-118 394.7 13.0 3.9e-118 394.4 13.0 1.0 1 0 0 1 1 1 1 TMPIT-like protein Egg_lysin PF01303.17 KER34286.1 - 0.00094 19.4 0.2 0.0022 18.2 0.2 1.5 1 0 0 1 1 1 1 Egg lysin (Sperm-lysin) MFS_1 PF07690.16 KER34287.1 - 1.2e-20 73.8 29.9 1.2e-20 73.8 29.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KER34287.1 - 1.7e-07 30.0 17.6 8.1e-06 24.4 3.2 3.2 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KER34287.1 - 0.0009 18.2 5.6 0.0009 18.2 5.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_47 PF01532.20 KER34289.1 - 3.9e-108 362.3 0.0 1e-107 360.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 SURF4 PF02077.15 KER34291.1 - 5.5e-88 295.0 14.5 1.4e-54 185.5 3.5 2.1 2 0 0 2 2 2 2 SURF4 family DoxX PF07681.12 KER34291.1 - 0.016 15.8 0.7 0.016 15.8 0.7 3.2 3 0 0 3 3 3 0 DoxX Helicase_C_2 PF13307.6 KER34292.1 - 1.3e-44 152.4 0.0 3.5e-44 151.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 KER34292.1 - 4.2e-39 134.2 1.5 1.5e-35 122.6 0.4 2.5 2 1 0 2 2 2 2 Helical and beta-bridge domain DEAD_2 PF06733.15 KER34292.1 - 4.7e-34 117.5 2.6 2.9e-30 105.2 2.6 2.5 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KER34292.1 - 2.8e-05 24.2 0.1 0.00049 20.1 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KER34292.1 - 0.014 14.8 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 KER34292.1 - 0.05 13.9 0.2 17 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Prosystemin PF07376.11 KER34293.1 - 0.053 13.0 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Prosystemin Lipocalin PF00061.23 KER34294.1 - 1.1e-21 77.6 4.9 1.3e-21 77.3 4.9 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 KER34294.1 - 1.8e-05 24.7 1.8 2.7e-05 24.1 1.8 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Band_7 PF01145.25 KER34295.1 - 1.8e-32 112.8 0.6 2.3e-32 112.4 0.6 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KER34295.1 - 0.00083 19.1 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 KER34295.1 - 0.049 14.0 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 Phage protein Gp68 NUDIX PF00293.28 KER34298.1 - 2.8e-08 33.9 0.1 9e-08 32.2 0.1 1.7 1 1 1 2 2 2 1 NUDIX domain UPF0061 PF02696.14 KER34299.1 - 2.5e-116 389.2 0.0 2.1e-115 386.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XendoU PF09412.10 KER34299.1 - 0.016 14.4 1.8 0.018 14.3 0.1 1.7 2 0 0 2 2 2 0 Endoribonuclease XendoU InaF-motif PF15018.6 KER34300.1 - 6.1 6.8 5.7 35 4.4 0.5 2.5 2 0 0 2 2 2 0 TRP-interacting helix Cpn60_TCP1 PF00118.24 KER34302.1 - 5.1e-168 559.7 14.7 2.1e-75 254.2 2.6 3.0 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family DKCLD PF08068.12 KER34302.1 - 0.022 14.8 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 DKCLD (NUC011) domain Hypoth_Ymh PF09509.10 KER34302.1 - 0.12 12.3 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Ribosomal_L9_N PF01281.19 KER34302.1 - 0.54 9.9 4.2 33 4.2 0.4 3.5 4 0 0 4 4 4 0 Ribosomal protein L9, N-terminal domain Armet PF10208.9 KER34304.1 - 1.3e-34 119.2 7.2 1.6e-34 118.9 7.2 1.1 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding DUF5332 PF17266.2 KER34304.1 - 0.0017 18.0 1.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5332) zf-AD PF07776.15 KER34305.1 - 0.014 15.6 0.1 0.067 13.4 0.1 2.2 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Zn_Tnp_IS1 PF03811.13 KER34305.1 - 0.04 13.7 4.0 0.11 12.3 0.2 3.2 2 0 0 2 2 2 0 InsA N-terminal domain zf-C2HE PF16278.5 KER34305.1 - 1.4 9.4 9.5 6.7 7.2 0.0 5.1 6 0 0 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 KER34305.1 - 3.8 7.6 12.7 3.9 7.6 0.0 4.2 4 0 0 4 4 4 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KER34305.1 - 5.6 8.1 65.5 0.98 10.4 0.7 10.4 10 0 0 10 10 10 0 C2H2-type zinc finger FOXP-CC PF16159.5 KER34305.1 - 7.5 7.3 46.7 0.17 12.5 2.0 7.7 7 2 2 9 9 9 0 FOXP coiled-coil domain CBM_21 PF03370.13 KER34306.1 - 3.3e-20 72.3 0.0 5.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KER34306.1 - 5e-11 43.0 0.1 9.6e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Cadherin PF00028.17 KER34307.1 - 2.5e-48 162.4 4.3 1.4e-11 44.7 0.4 11.0 9 2 0 9 9 9 5 Cadherin domain Cadherin_2 PF08266.12 KER34307.1 - 0.00094 19.0 0.0 13 5.7 0.0 4.2 4 0 0 4 4 4 2 Cadherin-like CH PF00307.31 KER34309.1 - 8.6e-69 228.6 0.0 1.5e-20 73.4 0.1 4.6 4 0 0 4 4 4 4 Calponin homology (CH) domain CH_2 PF06294.11 KER34309.1 - 0.00038 20.5 0.1 0.02 15.0 0.0 3.0 3 0 0 3 3 3 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 KER34309.1 - 0.0036 17.1 0.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 1 CAMSAP CH domain Glyco_hydro_129 PF11308.8 KER34311.1 - 0.13 11.4 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Ank_2 PF12796.7 KER34313.1 - 1.7e-26 92.6 1.9 3.7e-12 46.7 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KER34313.1 - 1.5e-24 85.7 9.8 2.4e-08 34.1 0.4 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KER34313.1 - 1e-22 79.5 8.1 2.3e-05 24.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KER34313.1 - 1.8e-21 76.2 8.0 2.5e-05 24.7 1.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KER34313.1 - 2.9e-18 64.0 8.3 9.9e-05 22.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat PAX PF00292.18 KER34315.1 - 2e-35 121.4 1.5 3.5e-35 120.6 0.8 1.8 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.6 KER34315.1 - 8.7e-07 28.6 0.0 2.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KER34315.1 - 0.00013 22.0 0.0 0.0004 20.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KER34315.1 - 0.0002 21.3 0.1 0.00076 19.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix Homeodomain PF00046.29 KER34315.1 - 0.0025 17.6 0.4 0.0025 17.6 0.4 2.6 2 0 0 2 2 2 1 Homeodomain HTH_38 PF13936.6 KER34315.1 - 0.099 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cadherin PF00028.17 KER34318.1 - 1.7e-68 227.1 4.5 1.1e-16 61.0 0.1 8.9 8 2 0 8 8 8 6 Cadherin domain Cadherin_2 PF08266.12 KER34318.1 - 5.5e-10 39.0 0.8 0.0032 17.3 0.3 5.6 4 1 0 4 4 4 3 Cadherin-like Cadherin_3 PF16184.5 KER34318.1 - 1.1e-05 25.4 10.5 0.068 13.2 0.0 6.2 6 2 0 6 6 6 2 Cadherin-like MDM10 PF12519.8 KER34318.1 - 0.02 13.7 2.0 0.036 12.9 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Melibiase PF02065.18 KER34318.1 - 0.046 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Melibiase GLTSCR1 PF15249.6 KER34319.1 - 0.0098 16.3 0.9 0.025 15.0 0.9 1.7 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein DFP PF04127.15 KER34322.1 - 1.4e-12 47.8 0.0 4.3e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Ran_BP1 PF00638.18 KER34323.1 - 6.3e-87 288.0 0.2 3.5e-31 108.0 0.0 5.4 4 1 0 4 4 4 4 RanBP1 domain zf-RanBP PF00641.18 KER34323.1 - 2.2e-11 42.8 16.0 8.2e-09 34.6 3.8 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others WH1 PF00568.23 KER34323.1 - 8e-05 22.5 0.0 0.00084 19.3 0.0 2.6 3 0 0 3 3 3 1 WH1 domain TPR_19 PF14559.6 KER34323.1 - 0.063 13.8 1.0 21 5.7 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Spc7 PF08317.11 KER34323.1 - 0.064 12.1 3.4 0.12 11.2 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Synaptobrevin PF00957.21 KER34323.1 - 0.091 12.6 5.5 0.062 13.1 3.1 1.9 2 0 0 2 2 2 0 Synaptobrevin TPR_16 PF13432.6 KER34323.1 - 0.14 12.8 0.2 0.83 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0242 PF06785.11 KER34323.1 - 0.15 12.2 3.6 0.38 10.8 3.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VID27_PH PF17747.1 KER34323.1 - 0.15 12.3 0.0 53 4.1 0.0 3.3 3 0 0 3 3 3 0 VID27 PH-like domain Lig_C PF18330.1 KER34323.1 - 0.18 11.8 0.0 39 4.3 0.0 3.3 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region BNIP2 PF12496.8 KER34323.1 - 0.19 12.1 0.8 0.76 10.2 0.8 2.0 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PMC2NT PF08066.12 KER34323.1 - 0.42 11.3 2.2 1.4 9.7 2.2 1.8 1 0 0 1 1 1 0 PMC2NT (NUC016) domain KxDL PF10241.9 KER34323.1 - 0.49 10.7 4.5 4.7 7.6 4.9 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein SKA1 PF07160.12 KER34323.1 - 0.84 9.4 3.0 2 8.2 3.0 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DZR PF12773.7 KER34323.1 - 0.97 9.5 7.0 6.2 6.9 7.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon RAP80_UIM PF18282.1 KER34323.1 - 2.7 7.8 8.0 0.077 12.8 0.7 2.2 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Trypan_glycop PF00913.19 KER34323.1 - 3.2 6.9 8.0 5.2 6.2 2.7 2.4 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) Syntaxin PF00804.25 KER34324.1 - 4.3e-47 160.4 15.6 6.4e-47 159.8 15.6 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KER34324.1 - 1e-08 35.1 0.1 1e-08 35.1 0.1 2.9 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 KER34324.1 - 5.4e-07 29.9 6.2 5.4e-07 29.9 6.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 KER34324.1 - 0.0038 17.8 1.5 0.0038 17.8 1.5 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal AAA_13 PF13166.6 KER34324.1 - 0.036 12.7 15.0 0.032 12.9 14.2 1.3 1 1 0 1 1 1 0 AAA domain FUSC PF04632.12 KER34324.1 - 0.1 11.1 9.1 0.03 12.9 2.7 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family FlaC_arch PF05377.11 KER34324.1 - 0.16 12.4 5.8 7.9 7.0 1.2 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 KER34324.1 - 0.37 11.4 4.4 2.2 8.8 0.2 2.6 2 0 0 2 2 2 0 YtxH-like protein DUF2970 PF11174.8 KER34324.1 - 0.46 10.4 3.5 0.88 9.5 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF5063 PF16702.5 KER34324.1 - 0.61 10.5 4.5 0.62 10.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5063) NPV_P10 PF05531.12 KER34324.1 - 2 9.0 6.7 13 6.4 1.0 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KER34324.1 - 3.6 8.4 11.4 3.8 8.3 0.3 3.3 2 1 0 3 3 3 0 Occludin homology domain Asp4 PF16996.5 KER34324.1 - 5.3 6.9 5.6 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 DUF848 PF05852.11 KER34324.1 - 6.3 6.9 15.1 0.36 10.9 4.3 2.5 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fez1 PF06818.15 KER34324.1 - 8.5 6.8 15.8 6.1 7.3 0.7 2.2 2 0 0 2 2 2 0 Fez1 zf-SCNM1 PF15803.5 KER34325.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 SPOC PF07744.13 KER34326.1 - 2.1e-37 128.4 0.0 4.8e-37 127.2 0.0 1.6 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 KER34326.1 - 1.1e-21 76.4 0.0 1.9e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KER34326.1 - 0.031 14.4 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif ABC_membrane PF00664.23 KER34328.1 - 3.7e-101 338.4 17.0 2e-52 178.6 7.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KER34328.1 - 8.4e-65 217.4 0.0 3e-34 118.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KER34328.1 - 3.7e-12 46.1 1.5 0.0064 15.9 0.1 4.8 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KER34328.1 - 4.5e-12 46.4 0.0 0.00013 22.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KER34328.1 - 5.7e-09 36.1 0.0 0.00074 19.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KER34328.1 - 7.1e-09 36.3 0.2 0.00091 19.6 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KER34328.1 - 1.2e-06 28.6 0.0 0.15 11.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KER34328.1 - 2.7e-06 26.8 0.0 0.08 12.1 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 KER34328.1 - 2.9e-06 26.9 0.0 0.032 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KER34328.1 - 3e-06 27.8 0.0 0.038 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KER34328.1 - 7.1e-06 26.1 0.1 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 KER34328.1 - 9.5e-06 25.7 0.0 0.25 11.3 0.0 3.7 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KER34328.1 - 3.6e-05 23.6 0.1 0.23 11.2 0.1 3.6 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 KER34328.1 - 6e-05 22.5 0.0 2.7 7.4 0.0 4.3 4 0 0 4 4 4 1 Bacterial TniB protein SbcCD_C PF13558.6 KER34328.1 - 0.00016 21.8 2.3 0.29 11.4 0.1 3.7 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KER34328.1 - 0.00023 21.2 0.0 0.98 9.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 KER34328.1 - 0.00024 20.7 0.1 5.5 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KER34328.1 - 0.00035 20.1 0.2 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KER34328.1 - 0.00036 21.1 0.0 0.59 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KER34328.1 - 0.00044 20.7 0.4 1.9 8.9 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KER34328.1 - 0.00067 20.0 0.0 1.2 9.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_15 PF13175.6 KER34328.1 - 0.00071 19.4 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain tRNA_lig_kinase PF08303.11 KER34328.1 - 0.00072 19.7 0.2 1.2 9.3 0.0 2.9 3 0 0 3 3 2 1 tRNA ligase kinase domain IstB_IS21 PF01695.17 KER34328.1 - 0.00087 19.1 0.3 1.7 8.3 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_33 PF13671.6 KER34328.1 - 0.0012 19.0 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KER34328.1 - 0.0013 18.0 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FeoB_N PF02421.18 KER34328.1 - 0.0024 17.4 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B PRK PF00485.18 KER34328.1 - 0.0026 17.5 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KER34328.1 - 0.003 16.8 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.6 KER34328.1 - 0.0036 17.6 0.2 0.86 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KER34328.1 - 0.0047 16.6 0.0 0.43 10.2 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KER34328.1 - 0.0059 16.5 0.0 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KER34328.1 - 0.0074 16.3 0.0 0.76 9.8 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KER34328.1 - 0.015 15.0 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KER34328.1 - 0.03 13.5 0.0 7.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KER34328.1 - 0.036 13.8 0.0 11 5.7 0.0 3.1 4 0 0 4 4 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 KER34328.1 - 0.044 13.0 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain MeaB PF03308.16 KER34328.1 - 0.057 12.4 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KER34328.1 - 0.09 13.2 0.1 11 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF1385 PF07136.11 KER34328.1 - 0.098 11.9 0.3 0.22 10.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) dNK PF01712.19 KER34328.1 - 0.15 11.9 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 KER34328.1 - 0.16 11.8 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRKCSH PF07915.13 KER34330.1 - 8.3e-24 84.4 7.7 2.2e-12 47.8 1.1 3.2 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KER34330.1 - 3.7e-12 46.2 1.0 4.6e-06 26.4 0.8 2.9 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein Ribosomal_L39 PF00832.20 KER34331.1 - 7.2e-20 70.3 14.2 1.3e-19 69.5 14.2 1.5 1 0 0 1 1 1 1 Ribosomal L39 protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Opisthorchis_viverrini-OpiViv1.0/GCA_000715545.1_OpiViv1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Opisthorchis_viverrini-OpiViv1.0/GCA_000715545.1_OpiViv1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Opisthorchis_viverrini-OpiViv1.0/GCA_000715545.1_OpiViv1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Opisthorchis_viverrini-OpiViv1.0/GCA_000715545.1_OpiViv1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 20:49:02 2019 # [ok]