# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- tRNA-synt_1b PF00579.25 CDS25235.1 - 5.6e-64 216.3 0.0 9.7e-52 176.1 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 CDS25235.1 - 3.8e-08 33.3 0.3 1e-07 32.0 0.3 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain NPL4 PF05021.15 CDS25237.1 - 1.2e-86 290.9 0.0 1.8e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CDS25237.1 - 2e-50 170.7 0.0 3.7e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CDS25237.1 - 1.3e-13 51.2 0.1 2.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 CDS25237.1 - 8e-06 25.1 1.3 8e-06 25.1 1.3 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others His_Phos_1 PF00300.22 CDS25238.1 - 3.2e-17 62.9 0.3 5.7e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SBF PF01758.16 CDS25241.1 - 2.2e-33 115.6 11.9 2.2e-33 115.6 11.9 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 CDS25241.1 - 4.9e-12 45.8 8.2 4.9e-12 45.8 8.2 1.6 2 0 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) DUF2752 PF10825.8 CDS25241.1 - 0.065 13.3 1.9 0.51 10.4 1.9 2.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Utp11 PF03998.13 CDS25242.1 - 6.1e-47 160.6 10.7 7.6e-47 160.3 10.7 1.1 1 0 0 1 1 1 1 Utp11 protein DUF4269 PF14091.6 CDS25242.1 - 0.085 13.1 0.4 0.45 10.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4269) Cauli_AT PF03233.13 CDS25242.1 - 0.14 12.1 2.5 0.47 10.4 0.0 2.5 2 1 1 3 3 3 0 Aphid transmission protein MMR_HSR1 PF01926.23 CDS25243.1 - 3.5e-18 65.8 0.0 6.3e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDS25243.1 - 3.1e-15 56.1 0.3 2.3e-14 53.2 0.3 2.0 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 CDS25243.1 - 3.5e-10 39.6 0.0 1.1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS25243.1 - 0.0025 17.9 0.3 0.47 10.5 0.1 2.4 1 1 1 2 2 2 2 Dynamin family Arf PF00025.21 CDS25243.1 - 0.0076 15.7 0.0 0.19 11.2 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 CDS25243.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CDS25243.1 - 0.022 14.5 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 CDS25243.1 - 0.11 12.1 0.1 4 6.9 0.0 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CDS25243.1 - 0.17 11.9 0.1 2.8 8.0 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Helicase_C PF00271.31 CDS25244.1 - 6.9e-14 52.1 0.0 4.8e-13 49.4 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDS25244.1 - 4.2e-11 43.1 0.0 9.9e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDS25244.1 - 6.4e-09 35.8 0.0 1.7e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 CDS25244.1 - 9.1e-07 29.1 0.1 1.9e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_19 PF13245.6 CDS25244.1 - 0.00036 20.9 0.0 0.0009 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS25244.1 - 0.0008 19.7 0.4 0.0047 17.2 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDS25244.1 - 0.0085 16.1 0.1 0.16 12.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDS25244.1 - 0.026 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CDS25244.1 - 0.053 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 CDS25244.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 CDS25244.1 - 0.081 12.1 0.0 0.72 9.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 CDS25244.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CDS25244.1 - 0.13 12.8 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 CDS25244.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SQS_PSY PF00494.19 CDS25245.1 - 2.9e-29 102.4 0.2 3.6e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Perilipin PF03036.16 CDS25245.1 - 0.055 12.5 0.2 0.072 12.1 0.2 1.1 1 0 0 1 1 1 0 Perilipin family DUF3403 PF11883.8 CDS25245.1 - 0.72 10.0 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) Na_H_Exchanger PF00999.21 CDS25246.1 - 1.4e-50 172.2 37.1 1.7e-50 171.9 37.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CENP-T_C PF15511.6 CDS25250.2 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDS25250.2 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDS25250.2 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CDS25250.2 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS25250.2 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS25250.2 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDS25250.2 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDS25250.2 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) LIM PF00412.22 CDS25251.1 - 1.8e-57 191.4 98.2 1.7e-13 50.6 4.5 8.0 7 2 0 7 7 7 6 LIM domain PET PF06297.14 CDS25251.1 - 7.5e-06 26.2 0.1 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 PET Domain Pkinase PF00069.25 CDS25252.1 - 5.6e-41 140.6 0.1 1.6e-40 139.1 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25252.1 - 7.6e-21 74.5 0.0 1.5e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 CDS25253.1 - 3.5e-52 174.3 5.7 1.5e-18 66.5 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_Zc3h12a PF11977.8 CDS25254.1 - 7.1e-27 94.1 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF1363 PF07101.11 CDS25254.1 - 0.1 12.9 0.3 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) zf-C3HC4_2 PF13923.6 CDS25255.1 - 3.3e-10 39.6 5.1 7.2e-10 38.5 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS25255.1 - 2.2e-08 33.8 4.3 4.5e-08 32.8 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS25255.1 - 2.5e-08 33.7 6.5 5.3e-08 32.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS25255.1 - 9.7e-08 32.2 5.5 9.7e-08 32.2 5.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS25255.1 - 3.2e-07 30.3 6.4 9.3e-07 28.8 6.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDS25255.1 - 6.3e-06 26.4 4.9 2.3e-05 24.6 4.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS25255.1 - 6.7e-06 26.0 4.7 1.2e-05 25.1 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDS25255.1 - 7.8e-06 25.9 7.7 1.9e-05 24.7 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 CDS25255.1 - 0.00028 21.0 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 CDS25255.1 - 0.00043 20.1 4.4 0.00043 20.1 4.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CDS25255.1 - 0.0063 16.6 2.7 0.0063 16.6 2.7 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CDS25255.1 - 0.04 14.0 1.0 0.04 14.0 1.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDS25255.1 - 0.16 11.8 3.8 0.4 10.5 3.8 1.7 1 1 0 1 1 1 0 RING-like zinc finger Ank_2 PF12796.7 CDS25258.2 - 1.2e-25 89.9 1.3 1.2e-10 41.8 0.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25258.2 - 1.5e-25 89.3 0.5 4e-10 40.0 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS25258.2 - 1.1e-19 70.2 0.8 2.9e-07 30.6 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS25258.2 - 2.8e-17 61.0 2.3 0.01 16.3 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 CDS25258.2 - 2.3e-12 46.8 3.9 0.0011 19.3 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeat PDZ PF00595.24 CDS25258.2 - 9.4e-10 38.7 0.2 2.5e-09 37.3 0.2 1.7 1 1 0 1 1 1 1 PDZ domain FERM_f0 PF16511.5 CDS25258.2 - 2.4e-08 34.2 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM PDZ_6 PF17820.1 CDS25258.2 - 9.2e-06 25.4 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS25258.2 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Presenilin PF01080.17 CDS25259.2 - 6.5 5.4 4.8 9.8 4.8 4.8 1.3 1 0 0 1 1 1 0 Presenilin MBOAT PF03062.19 CDS25260.2 - 8e-25 87.9 20.0 1.6e-24 86.9 20.0 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDS25260.2 - 3e-05 24.2 6.3 7.9e-05 22.9 6.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Arteri_nucleo PF01481.16 CDS25260.2 - 0.066 13.5 0.3 0.13 12.6 0.3 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Ig_3 PF13927.6 CDS25261.2 - 8.7e-29 100.0 4.3 6.3e-05 23.5 0.0 9.4 7 2 0 7 7 7 5 Immunoglobulin domain I-set PF07679.16 CDS25261.2 - 7.7e-17 61.1 0.0 0.0018 18.3 0.0 7.5 7 1 0 7 7 7 3 Immunoglobulin I-set domain ig PF00047.25 CDS25261.2 - 2.4e-16 59.7 0.1 0.035 14.3 0.0 8.5 7 2 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 CDS25261.2 - 1.2e-15 57.6 0.2 0.00054 20.1 0.0 6.8 7 0 0 7 7 7 4 Immunoglobulin V-set domain fn3 PF00041.21 CDS25261.2 - 5e-14 52.4 0.1 6.8e-06 26.3 0.3 4.2 4 0 0 4 4 4 2 Fibronectin type III domain Ig_2 PF13895.6 CDS25261.2 - 1.2e-08 35.1 10.4 0.0092 16.3 0.0 8.4 8 3 1 9 9 9 1 Immunoglobulin domain Ig_6 PF18452.1 CDS25261.2 - 0.0022 17.5 0.2 0.62 9.7 0.0 3.7 4 0 0 4 4 4 1 Immunoglobulin domain C2-set_2 PF08205.12 CDS25261.2 - 0.012 15.7 0.9 0.12 12.5 0.0 3.1 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.11 CDS25261.2 - 0.17 11.8 0.2 2 8.4 0.3 2.5 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ribosomal_S9 PF00380.19 CDS25262.2 - 4.2e-23 82.2 0.0 7.8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TSGA13 PF14994.6 CDS25262.2 - 0.098 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein Ribosomal_S4e PF00900.20 CDS25263.2 - 7.4e-36 121.9 2.5 1.2e-35 121.2 2.5 1.3 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 CDS25263.2 - 3.8e-20 71.7 4.3 6.5e-20 71.0 4.3 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CDS25263.2 - 8.3e-08 31.8 0.1 2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CDS25263.2 - 1.4e-05 24.9 0.3 4e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 KOW motif 40S_S4_C PF16121.5 CDS25263.2 - 9.7e-05 21.9 0.1 0.00067 19.3 0.1 2.3 3 0 0 3 3 3 1 40S ribosomal protein S4 C-terminus Sipho_tail PF05709.11 CDS25263.2 - 0.0005 19.6 0.1 0.00061 19.3 0.1 1.2 1 0 0 1 1 1 1 Phage tail protein PP-binding PF00550.25 CDS25265.2 - 4.1e-05 23.9 0.0 6.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site COX5B PF01215.19 CDS25266.2 - 2.8e-08 33.5 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF488 PF04343.13 CDS25266.2 - 0.023 15.3 0.3 0.064 13.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF488 MCD_N PF17408.2 CDS25266.2 - 0.1 12.7 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain SpoIIID PF12116.8 CDS25266.2 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Epsilon_antitox PF08998.11 CDS25266.2 - 0.16 12.3 1.5 0.34 11.2 0.1 2.1 2 1 0 2 2 2 0 Bacterial epsilon antitoxin hDGE_amylase PF14701.6 CDS25267.1 - 2.7e-127 425.5 0.0 4.2e-127 424.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CDS25267.1 - 1.5e-104 350.0 0.0 2.6e-104 349.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CDS25267.1 - 2.3e-71 240.4 0.0 3.6e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CDS25267.1 - 2e-14 53.5 0.4 3.6e-14 52.7 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CDS25267.1 - 0.037 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Ras PF00071.22 CDS25268.1 - 8.6e-55 184.8 0.3 1.1e-54 184.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS25268.1 - 7.7e-33 113.3 0.2 1.2e-32 112.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS25268.1 - 7e-16 58.2 0.1 8.8e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS25268.1 - 1e-05 25.0 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS25268.1 - 6.3e-05 23.0 0.1 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDS25268.1 - 0.00015 21.6 0.2 0.0014 18.3 0.1 2.1 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 CDS25268.1 - 0.00048 19.7 0.1 0.0013 18.3 0.0 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDS25268.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GATase_2 PF00310.21 CDS25270.1 - 1.3e-161 538.0 0.0 1.7e-161 537.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CDS25270.1 - 5.7e-149 496.2 2.0 5.1e-147 489.8 1.1 2.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CDS25270.1 - 2.3e-111 371.8 0.0 6.2e-109 363.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CDS25270.1 - 1.6e-71 239.8 1.1 3.3e-71 238.8 1.1 1.6 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CDS25270.1 - 5.9e-27 94.7 0.0 4e-26 91.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CDS25270.1 - 1.2e-18 66.9 0.6 3e-18 65.6 0.6 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 CDS25270.1 - 6.2e-08 32.2 0.0 8e-05 22.0 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDS25270.1 - 1.1e-07 32.2 0.4 0.0012 19.3 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDS25270.1 - 2.9e-07 30.6 0.3 1.3e-06 28.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDS25270.1 - 1.9e-05 23.5 1.3 0.00011 21.0 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CDS25270.1 - 5.2e-05 22.8 4.2 6.5e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDS25270.1 - 8.2e-05 21.9 0.3 8.2e-05 21.9 0.3 1.8 2 0 0 2 2 1 1 FAD binding domain DAO PF01266.24 CDS25270.1 - 9.4e-05 22.1 2.1 0.0047 16.5 0.4 3.4 4 0 0 4 4 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDS25270.1 - 9.7e-05 21.7 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 Thi4 family AdoHcyase_NAD PF00670.21 CDS25270.1 - 0.0001 22.4 0.4 0.65 10.1 0.1 2.6 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 CDS25270.1 - 0.00011 22.6 0.5 0.027 14.9 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 CDS25270.1 - 0.0002 20.6 1.5 0.053 12.6 0.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CDS25270.1 - 0.00058 19.2 0.6 0.0012 18.2 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.18 CDS25270.1 - 0.00092 18.3 4.1 0.11 11.5 1.9 3.6 4 0 0 4 4 4 1 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.21 CDS25270.1 - 0.0011 18.3 5.5 0.04 13.2 0.0 2.8 3 0 0 3 3 2 2 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 CDS25270.1 - 0.002 17.5 0.3 0.0055 16.0 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 CDS25270.1 - 0.0026 17.1 0.0 0.33 10.3 0.0 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 CDS25270.1 - 0.027 14.3 0.1 6 6.7 0.0 2.8 3 0 0 3 3 2 0 YjeF-related protein N-terminus FMO-like PF00743.19 CDS25270.1 - 0.085 11.3 0.7 7.1 4.9 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 CDS25270.1 - 0.099 11.7 0.4 0.18 10.8 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein End_tail_spike PF12219.8 CDS25270.1 - 0.13 12.4 0.4 52 3.9 0.0 3.3 3 0 0 3 3 3 0 Catalytic domain of bacteriophage endosialidase Shikimate_DH PF01488.20 CDS25270.1 - 0.17 11.9 0.3 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CDS25270.1 - 0.23 11.5 3.1 3.2 7.7 0.2 4.2 5 0 0 5 5 4 0 FAD-NAD(P)-binding PDEase_I PF00233.19 CDS25271.1 - 6.6e-86 287.9 1.3 6.6e-86 287.9 1.3 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 CDS25271.1 - 1.7e-37 128.7 0.5 3.9e-37 127.5 0.5 1.7 1 0 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) ALMS_repeat PF18727.1 CDS25271.1 - 0.02 14.7 2.2 0.046 13.6 2.2 1.6 1 0 0 1 1 1 0 Alstrom syndrome repeat HTH_24 PF13412.6 CDS25272.1 - 0.00023 20.6 0.3 0.0016 17.9 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_48 PF17906.1 CDS25272.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_AsnC-type PF13404.6 CDS25272.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 CDS25272.1 - 0.037 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 CDS25272.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 CDS25272.1 - 0.089 12.9 0.5 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix Perilipin PF03036.16 CDS25273.1 - 0.026 13.5 0.2 0.052 12.6 0.2 1.4 1 0 0 1 1 1 0 Perilipin family Caskin-Pro-rich PF16907.5 CDS25273.1 - 0.034 14.6 1.7 0.034 14.6 1.7 1.9 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Ada3 PF10198.9 CDS25273.1 - 0.074 13.2 0.4 7.7 6.7 0.1 2.8 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 I-set PF07679.16 CDS25276.1 - 6.7e-09 35.7 0.1 1.3e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 CDS25276.1 - 2.2e-07 31.0 1.3 3.3e-07 30.4 0.2 1.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.6 CDS25276.1 - 8e-07 29.6 0.4 2e-06 28.3 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDS25276.1 - 2e-06 27.9 1.2 3.3e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CDS25276.1 - 0.0046 17.3 0.3 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_6 PF18452.1 CDS25276.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Gryzun-like PF12742.7 CDS25276.1 - 0.12 12.4 0.5 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking DUF4830 PF16112.5 CDS25276.1 - 0.14 12.6 0.8 0.49 10.9 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4830) Mss4 PF04421.13 CDS25277.2 - 2.3e-22 78.9 0.0 4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Mss4 protein Guanylate_cyc PF00211.20 CDS25278.2 - 3.5e-57 193.0 0.0 5.9e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDS25278.2 - 1e-27 97.1 0.0 1.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25278.2 - 4.7e-23 81.9 0.1 9.6e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 CDS25278.2 - 0.0045 16.4 0.9 0.0094 15.4 0.9 1.5 1 0 0 1 1 1 1 Heme NO binding associated LLGL PF08366.13 CDS25279.2 - 4.7e-23 81.5 0.0 1.1e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.32 CDS25279.2 - 0.00073 20.3 19.4 0.5 11.3 0.4 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat Synaptobrevin PF00957.21 CDS25279.2 - 0.014 15.1 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 Synaptobrevin Med18 PF09637.10 CDS25280.2 - 8.1e-05 22.6 1.9 0.0075 16.1 0.0 2.6 2 1 1 3 3 3 2 Med18 protein BHD_3 PF10405.9 CDS25282.2 - 2.2e-25 88.8 0.1 2.3e-24 85.6 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CDS25282.2 - 1.2e-18 66.7 0.1 4.7e-18 64.8 0.1 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CDS25282.2 - 2.6e-11 44.3 0.1 2.6e-11 44.3 0.1 4.3 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Hexapep PF00132.24 CDS25282.2 - 0.00019 21.0 6.8 0.038 13.7 0.3 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Lipase_3 PF01764.25 CDS25283.2 - 2.2e-11 43.8 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CDS25283.2 - 0.048 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDS25283.2 - 0.13 12.8 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4817 PF16087.5 CDS25283.2 - 0.17 11.7 0.8 0.49 10.2 0.8 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Lipase_3 PF01764.25 CDS25285.2 - 1.8e-12 47.3 0.0 4.1e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CDS25285.2 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Arfaptin PF06456.13 CDS25286.2 - 1.3e-73 247.4 4.3 2e-73 246.8 4.3 1.3 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 CDS25286.2 - 1.4e-05 24.9 1.2 9.8e-05 22.1 1.0 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CDS25286.2 - 5.9e-05 22.9 0.7 0.005 16.6 0.7 2.3 1 1 0 1 1 1 1 BAR domain of APPL family DUF3727 PF12527.8 CDS25287.2 - 0.081 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) Pkinase_Tyr PF07714.17 CDS25288.1 - 1.5e-80 270.2 0.0 2.7e-80 269.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25288.1 - 1.8e-34 119.3 0.0 2.1e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain fn3 PF00041.21 CDS25288.1 - 0.00061 20.1 0.4 0.12 12.7 0.1 3.5 3 0 0 3 3 3 1 Fibronectin type III domain Pkinase_fungal PF17667.1 CDS25288.1 - 0.0029 16.5 0.2 0.0099 14.7 0.2 1.7 1 1 0 2 2 2 1 Fungal protein kinase EpoR_lig-bind PF09067.10 CDS25288.1 - 0.062 13.5 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding Kdo PF06293.14 CDS25288.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDS25290.2 - 2.8e-127 423.6 0.0 9.9e-68 228.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25290.2 - 8e-70 235.1 0.0 1.4e-35 122.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS25290.2 - 3.5e-10 39.7 0.0 2.2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDS25290.2 - 5.7e-10 38.9 0.1 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS25290.2 - 2.6e-08 33.1 0.0 0.00053 18.9 0.0 2.5 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 CDS25290.2 - 2.8e-06 27.4 0.0 0.032 14.2 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 CDS25290.2 - 4.2e-06 27.4 1.1 1.7e-05 25.4 1.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 CDS25290.2 - 1.6e-05 24.7 0.1 1.1 8.8 0.0 3.2 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDS25290.2 - 2e-05 23.7 0.5 0.00022 20.3 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDS25290.2 - 2.6e-05 23.8 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CDS25290.2 - 0.0047 16.5 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 CDS25290.2 - 0.013 15.1 0.8 2.8 7.5 0.1 2.5 2 1 0 2 2 2 0 RIO1 family TED_complement PF07678.14 CDS25292.2 - 1.5e-29 103.1 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 CDS25292.2 - 1.3e-07 31.4 0.0 3.8e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 CDS25292.2 - 2.8e-07 30.9 0.0 7.3e-05 23.1 0.0 2.8 1 1 0 1 1 1 1 MG2 domain MG3 PF17791.1 CDS25292.2 - 2.9e-07 30.7 0.0 9e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Macroglobulin domain MG3 EGF_2 PF07974.13 CDS25292.2 - 0.0028 18.0 10.6 0.0028 18.0 10.6 3.3 3 0 0 3 3 3 1 EGF-like domain A2M_BRD PF07703.14 CDS25292.2 - 0.0063 16.9 0.0 0.31 11.4 0.0 2.9 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain EGF PF00008.27 CDS25292.2 - 6.8 7.1 8.7 29 5.1 5.9 2.9 2 0 0 2 2 2 0 EGF-like domain WD40 PF00400.32 CDS25293.2 - 6.2e-10 39.5 5.6 0.011 16.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Biotin_lipoyl PF00364.22 CDS25294.2 - 2e-20 72.4 3.2 2.5e-20 72.1 3.2 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDS25294.2 - 3.3e-06 26.8 0.1 0.018 14.9 0.0 2.1 2 0 0 2 2 2 2 Biotin-lipoyl like QRPTase_N PF02749.16 CDS25294.2 - 0.0022 18.0 0.4 0.088 12.9 0.0 2.1 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF5561 PF17716.1 CDS25294.2 - 0.003 16.9 0.0 0.0032 16.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5561) E1-E2_ATPase PF00122.20 CDS25294.2 - 0.02 14.4 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 E1-E2 ATPase ATP-synt_ab_Xtn PF16886.5 CDS25294.2 - 0.027 14.3 0.3 0.035 13.9 0.3 1.2 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension PYNP_C PF07831.13 CDS25294.2 - 0.034 13.8 0.2 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF761 PF05553.11 CDS25294.2 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Cotton fibre expressed protein HlyD_3 PF13437.6 CDS25294.2 - 0.11 13.2 0.2 0.39 11.5 0.2 1.9 1 1 0 1 1 1 0 HlyD family secretion protein DNA_topoisoIV PF00521.20 CDS25295.2 - 4.1e-125 418.0 0.0 4.1e-125 418.0 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDS25295.2 - 7.6e-47 158.8 0.7 7.6e-47 158.8 0.7 2.6 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDS25295.2 - 4.7e-26 91.3 0.2 1.2e-25 90.0 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDS25295.2 - 3.5e-13 50.0 0.0 1.7e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDS25295.2 - 2.6e-06 27.6 0.0 1.1e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain ATG11 PF10377.9 CDS25295.2 - 0.89 9.6 4.2 0.33 11.0 0.1 2.5 2 0 0 2 2 2 0 Autophagy-related protein 11 DUF1840 PF08895.11 CDS25295.2 - 1.1 9.7 10.5 0.2 12.0 1.9 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) RRF PF01765.19 CDS25295.2 - 1.2 9.0 9.4 0.15 12.0 3.4 2.6 2 0 0 2 2 2 0 Ribosome recycling factor NUDIX PF00293.28 CDS25296.2 - 1.5e-08 34.8 0.1 2.4e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Orf78 PF06024.12 CDS25298.1 - 0.05 13.9 0.9 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) PAN_4 PF14295.6 CDS25298.1 - 0.11 12.4 1.0 0.42 10.6 0.1 2.3 2 0 0 2 2 2 0 PAN domain UNC45-central PF11701.8 CDS25299.1 - 8.4e-22 77.8 2.8 3.3e-21 75.8 0.0 3.3 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 CDS25299.1 - 1.2e-16 59.7 1.8 2.4e-05 24.0 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS25299.1 - 1.9e-16 58.8 0.1 7.2e-05 22.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS25299.1 - 2.1e-10 39.9 5.9 0.0026 17.9 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS25299.1 - 2.9e-09 36.5 0.1 0.0029 17.3 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 CDS25299.1 - 1.3e-07 31.8 1.4 2.5 8.9 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat Arm PF00514.23 CDS25299.1 - 1.2e-06 28.3 1.6 1.7 8.8 0.0 7.0 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat TPR_12 PF13424.6 CDS25299.1 - 4.2e-06 27.0 0.4 7.5e-05 22.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDS25299.1 - 5.4e-06 26.4 0.3 0.38 11.2 0.8 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS25299.1 - 1.1e-05 25.8 0.3 1.1e-05 25.8 0.3 3.0 3 1 1 4 4 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS25299.1 - 1.2e-05 25.0 0.3 0.14 12.2 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS25299.1 - 2.1e-05 24.5 0.6 0.0033 17.5 0.0 3.1 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CDS25299.1 - 4.3e-05 24.1 0.0 0.0034 18.0 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS25299.1 - 5.8e-05 23.6 0.0 0.34 11.8 0.0 4.3 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS25299.1 - 0.00011 22.4 0.8 0.0016 18.6 1.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.6 CDS25299.1 - 0.00066 20.0 4.5 7.9 7.0 0.0 6.4 5 1 2 7 7 7 1 HEAT repeats HEAT PF02985.22 CDS25299.1 - 0.0024 18.0 1.0 0.21 11.9 0.0 4.7 7 0 0 7 7 2 1 HEAT repeat TPR_21 PF09976.9 CDS25299.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 CDS25299.1 - 0.06 12.7 0.6 0.15 11.4 0.6 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit Herpes_UL49_1 PF03117.14 CDS25299.1 - 0.075 12.3 0.1 0.2 10.9 0.1 1.7 1 0 0 1 1 1 0 UL49 family SMC_N PF02463.19 CDS25301.1 - 9.5e-71 237.7 3.4 7.7e-38 130.1 2.2 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDS25301.1 - 7.2e-25 87.6 0.0 4.1e-24 85.1 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDS25301.1 - 6.8e-14 52.4 7.6 3.4e-07 30.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDS25301.1 - 7.9e-12 46.1 19.3 7.9e-12 46.1 19.3 5.6 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 CDS25301.1 - 1.1e-08 35.2 13.4 1.1e-08 35.2 13.4 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDS25301.1 - 4.2e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CDS25301.1 - 0.0005 20.6 0.1 0.0082 16.7 0.0 5.1 4 2 0 4 4 4 2 ABC transporter Thioredoxin PF00085.20 CDS25302.2 - 9.2e-19 67.4 0.2 1.1e-18 67.1 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDS25302.2 - 1.7e-05 25.1 0.0 2.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDS25302.2 - 0.00018 21.5 0.1 0.00018 21.4 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDS25302.2 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 CDS25302.2 - 0.03 14.1 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 CDS25302.2 - 0.04 14.4 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 CDS25302.2 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin PF00085.20 CDS25304.1 - 2.4e-14 53.2 0.2 2.8e-14 52.9 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDS25304.1 - 0.062 13.6 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CDS25304.1 - 0.13 12.7 0.2 0.35 11.4 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 CDS25305.1 - 1.5e-26 92.4 0.2 1.8e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDS25305.1 - 0.00013 22.2 0.1 0.00051 20.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CDS25305.1 - 0.00019 21.3 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDS25305.1 - 0.00053 20.4 0.1 0.003 18.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDS25305.1 - 0.00089 19.0 0.0 0.00099 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CDS25305.1 - 0.0025 17.5 0.1 0.0033 17.1 0.1 1.3 1 1 0 1 1 1 1 Redoxin Phosducin PF02114.16 CDS25305.1 - 0.0041 16.1 0.1 0.0046 15.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.6 CDS25305.1 - 0.0061 16.7 0.1 0.011 15.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CDS25305.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 CDS25305.1 - 0.2 11.4 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Rab5-bind PF09311.11 CDS25307.1 - 5.2e-26 91.8 35.5 7.1e-26 91.3 35.5 1.1 1 0 0 1 1 1 1 Rabaptin-like protein FYVE PF01363.21 CDS25307.1 - 6.9e-11 42.1 3.4 6.9e-11 42.1 3.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 CDS25307.1 - 1.8e-05 24.9 1.9 1.8e-05 24.9 1.9 3.4 2 2 1 4 4 4 1 FYVE-type zinc finger IBR PF01485.21 CDS25307.1 - 0.0011 19.2 2.6 0.0034 17.6 2.6 1.8 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Fib_alpha PF08702.10 CDS25307.1 - 0.86 9.8 20.1 0.95 9.6 1.6 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RseA_C PF03873.13 CDS25307.1 - 2.1 8.6 5.7 27 5.1 0.2 3.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain DUF1664 PF07889.12 CDS25307.1 - 6.5 6.8 15.0 2.3 8.3 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 CDS25307.1 - 7.8 6.9 21.1 0.22 11.9 2.3 4.5 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CFTR_R PF14396.6 CDS25309.1 - 0.0034 17.0 1.7 0.0034 17.0 1.7 1.9 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain PAT1 PF09770.9 CDS25309.1 - 0.0039 15.6 0.2 0.0039 15.6 0.2 2.7 3 0 0 3 3 3 1 Topoisomerase II-associated protein PAT1 Cript PF10235.9 CDS25310.1 - 4.1e-28 97.8 4.4 4.1e-28 97.8 4.4 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT Gin PF10764.9 CDS25310.1 - 6e-05 22.9 4.9 0.052 13.5 0.0 2.8 2 1 0 2 2 2 2 Inhibitor of sigma-G Gin DUF2039 PF10217.9 CDS25310.1 - 0.00056 20.2 10.3 0.0008 19.7 5.8 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DZR PF12773.7 CDS25310.1 - 0.019 15.0 11.8 0.055 13.5 5.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 CDS25310.1 - 0.24 11.6 13.6 0.078 13.1 6.2 2.8 2 1 1 3 3 3 0 Ribosomal protein L37e zinc_ribbon_2 PF13240.6 CDS25310.1 - 0.37 10.6 13.2 0.59 9.9 3.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Rhodanese_C PF12368.8 CDS25310.1 - 0.47 10.9 10.9 0.3 11.5 6.8 2.2 2 1 0 2 2 2 0 Rhodanase C-terminal NinF PF05810.12 CDS25310.1 - 0.52 10.2 11.2 0.091 12.6 2.6 2.8 2 1 1 3 3 3 0 NinF protein zf-C3HC4 PF00097.25 CDS25310.1 - 1.4 8.9 9.7 3.8 7.5 6.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PLATZ PF04640.14 CDS25310.1 - 2.2 9.0 9.8 0.34 11.6 1.1 2.6 2 1 1 3 3 3 0 PLATZ transcription factor ADK_lid PF05191.14 CDS25310.1 - 4.3 7.4 9.1 18 5.4 3.5 3.1 2 1 1 3 3 3 0 Adenylate kinase, active site lid ROS_MUCR PF05443.11 CDS25312.1 - 0.049 13.7 0.3 6 6.9 0.0 2.4 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein USP7_ICP0_bdg PF12436.8 CDS25312.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C2H2 PF00096.26 CDS25312.1 - 0.22 12.1 6.9 0.064 13.7 2.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS25312.1 - 3.6 8.7 6.3 1.6 9.7 2.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Asp_protease_2 PF13650.6 CDS25313.1 - 0.098 13.3 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Tubulin PF00091.25 CDS25314.1 - 2.4e-58 197.6 0.3 4.4e-58 196.7 0.1 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS25314.1 - 4.2e-23 81.9 0.0 7.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CDS25314.1 - 0.079 12.1 0.3 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Tubulin like NifU PF01106.17 CDS25315.1 - 1.6e-27 95.4 0.1 2.7e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CDS25315.1 - 3.7e-21 75.0 0.0 1.2e-20 73.4 0.0 1.8 1 1 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal Cullin PF00888.22 CDS25316.1 - 6.1e-203 675.8 1.3 9e-203 675.3 1.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS25316.1 - 5.7e-28 96.7 3.0 1.9e-27 95.1 3.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain ASC PF00858.24 CDS25317.1 - 4.6e-63 213.7 0.9 7.4e-63 213.0 0.0 1.7 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel MCU PF04678.13 CDS25318.2 - 1.3e-60 204.5 0.0 1.7e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter GTP-bdg_M PF16360.5 CDS25318.2 - 0.064 13.9 0.9 0.56 10.8 0.4 2.2 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DUF4140 PF13600.6 CDS25318.2 - 0.07 13.6 0.6 11 6.6 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.32 CDS25319.1 - 2.9e-11 43.7 4.4 0.0015 19.3 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25319.1 - 4.4e-08 33.3 0.6 0.014 15.7 0.0 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CDS25319.1 - 0.041 12.2 0.0 0.07 11.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HLH PF00010.26 CDS25320.1 - 3.6e-13 49.3 0.2 6.2e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 CDS25320.1 - 0.019 14.7 0.4 0.048 13.4 0.3 1.8 1 1 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain PAP2 PF01569.21 CDS25321.2 - 0.049 13.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily SWIM PF04434.17 CDS25321.2 - 0.17 11.6 1.7 0.54 10.0 1.7 1.9 1 0 0 1 1 1 0 SWIM zinc finger RNA_pol_Rpb2_6 PF00562.28 CDS25322.1 - 4.5e-127 424.3 0.1 6.5e-127 423.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDS25322.1 - 1.7e-65 220.3 0.0 2.5e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDS25322.1 - 5.2e-49 166.5 0.3 1.6e-48 164.8 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CDS25322.1 - 9.8e-33 112.4 0.1 2.5e-32 111.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CDS25322.1 - 4.6e-24 84.4 0.0 1.3e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CDS25322.1 - 2e-22 79.2 1.2 5.1e-22 77.9 1.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CDS25322.1 - 8.4e-16 58.3 1.9 2.1e-15 57.0 1.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Plectin PF00681.20 CDS25322.1 - 0.056 13.3 0.0 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Plectin repeat ELFV_dehydrog_N PF02812.18 CDS25323.1 - 1.3e-57 193.3 0.0 2.6e-57 192.3 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CDS25323.1 - 1.8e-52 178.5 0.0 1.3e-50 172.5 0.0 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 CDS25323.1 - 0.0003 20.9 0.0 0.00075 19.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDS25323.1 - 0.0091 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TP1 PF02079.16 CDS25323.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear transition protein 1 CH PF00307.31 CDS25324.1 - 1.9e-18 66.6 0.1 3.6e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS25324.1 - 1.4e-05 24.9 0.0 3.6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain DUF1654 PF07867.11 CDS25324.1 - 0.17 11.6 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) U-box PF04564.15 CDS25325.1 - 1.9e-30 104.8 0.1 4e-30 103.8 0.1 1.6 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 CDS25325.1 - 3.7e-20 72.5 17.8 1.7e-19 70.4 15.4 2.5 2 1 0 2 2 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_1 PF00515.28 CDS25325.1 - 4.7e-16 57.8 6.7 1.7e-10 40.2 1.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS25325.1 - 3.4e-13 48.6 5.2 2.3e-07 30.4 1.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS25325.1 - 3.9e-09 36.6 3.1 7.3e-09 35.7 3.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDS25325.1 - 5.6e-08 33.3 0.2 0.00062 20.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS25325.1 - 4.9e-07 30.0 2.3 4.9e-06 26.7 2.2 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS25325.1 - 1e-06 28.3 2.7 0.066 12.9 0.1 3.4 1 1 2 3 3 3 2 TPR repeat TPR_7 PF13176.6 CDS25325.1 - 1.3e-06 28.0 0.7 0.35 11.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS25325.1 - 2.4e-06 27.3 9.9 1.2e-05 25.1 0.6 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS25325.1 - 4.4e-06 26.7 2.9 0.011 16.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS25325.1 - 8.2e-06 26.2 4.0 8.7e-06 26.2 0.7 2.5 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS25325.1 - 2e-05 25.0 2.4 0.018 15.8 0.1 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 CDS25325.1 - 0.00014 21.9 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_6 PF13174.6 CDS25325.1 - 0.00017 22.0 1.4 1.2 9.9 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS25325.1 - 0.00028 21.0 1.7 0.017 15.3 0.2 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS25325.1 - 0.11 12.6 1.0 0.26 11.4 0.5 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat zf-C3HC4_3 PF13920.6 CDS25326.1 - 1.3e-09 37.8 8.0 1.3e-09 37.8 8.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS25326.1 - 1.7e-08 34.2 9.7 1.7e-08 34.2 9.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS25326.1 - 2.4e-08 33.7 9.4 7.2e-08 32.1 9.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS25326.1 - 2.7e-08 34.0 10.2 2.7e-08 34.0 10.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDS25326.1 - 2.1e-05 24.7 6.0 2.1e-05 24.7 6.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS25326.1 - 0.00059 19.7 8.1 0.00059 19.7 8.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 CDS25326.1 - 0.002 18.1 3.2 0.0045 16.9 3.2 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 CDS25326.1 - 0.0084 16.1 6.9 0.026 14.6 6.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger RPA_C PF08784.11 CDS25327.1 - 6.8e-14 52.4 0.1 1.2e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CDS25327.1 - 0.00067 19.6 0.6 0.0014 18.6 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_23 PF13384.6 CDS25327.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain RMI2 PF16100.5 CDS25327.1 - 0.036 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Rad21_Rec8_N PF04825.13 CDS25328.2 - 2e-38 130.9 0.0 3.9e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CDS25328.2 - 2.5e-11 42.7 0.0 1.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein zf-C3HC4 PF00097.25 CDS25331.1 - 2.1e-09 37.1 7.1 3.4e-09 36.4 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS25331.1 - 5.8e-09 36.1 7.5 8.9e-09 35.6 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS25331.1 - 2.9e-08 33.4 3.8 4.3e-08 32.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS25331.1 - 4.8e-07 29.5 8.2 7.7e-07 28.9 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS25331.1 - 0.00016 21.5 5.0 0.00027 20.8 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDS25331.1 - 0.00032 20.8 6.5 0.0039 17.3 7.3 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDS25331.1 - 0.00054 20.2 9.7 0.0021 18.3 9.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CDS25331.1 - 0.0026 17.8 3.7 0.0055 16.8 3.7 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 CDS25331.1 - 0.0087 16.1 8.9 0.017 15.1 8.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDS25331.1 - 0.013 15.6 1.4 0.022 14.8 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDS25331.1 - 0.051 13.5 6.1 0.11 12.4 6.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDS25331.1 - 0.076 12.8 5.6 0.14 12.0 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CDS25331.1 - 0.089 12.6 3.1 0.2 11.4 3.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 CDS25331.1 - 0.12 12.2 4.2 0.22 11.4 4.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD_2 PF13831.6 CDS25332.1 - 0.024 14.2 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 PHD-finger EF-hand_1 PF00036.32 CDS25333.1 - 6.6e-29 97.3 16.0 1.9e-07 30.2 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS25333.1 - 1.7e-25 89.2 12.0 1.5e-11 44.6 3.5 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS25333.1 - 5e-23 79.0 8.0 1.3e-05 24.7 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS25333.1 - 2.4e-21 75.3 10.1 3.9e-10 39.4 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS25333.1 - 1e-20 72.2 15.3 2.5e-05 23.5 0.5 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 CDS25333.1 - 8.5e-11 42.2 1.2 0.00012 22.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS25333.1 - 0.00018 21.7 0.7 0.038 14.3 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 CDS25333.1 - 0.011 15.5 2.4 4 7.4 0.5 2.6 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 CDS25333.1 - 0.016 15.2 7.6 1.2 9.1 1.3 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CDS25333.1 - 0.017 16.0 0.8 4.5 8.2 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain DsrH PF04077.12 CDS25333.1 - 0.035 14.2 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 DsrH like protein RPA_interact_M PF14767.6 CDS25333.1 - 0.095 13.3 1.6 0.26 11.9 1.6 1.7 1 0 0 1 1 1 0 Replication protein A interacting middle PMBR PF09373.10 CDS25333.1 - 0.12 12.6 0.8 1.3 9.3 0.0 3.2 5 0 0 5 5 3 0 Pseudomurein-binding repeat Dockerin_1 PF00404.18 CDS25333.1 - 0.42 10.8 13.8 0.13 12.5 4.1 2.7 2 1 0 2 2 2 0 Dockerin type I domain LPD25 PF18840.1 CDS25333.1 - 0.96 10.0 5.9 4.3 8.0 4.6 2.5 2 1 0 2 2 2 0 Large polyvalent protein associated domain 25 Glyco_hydro_47 PF01532.20 CDS25335.1 - 1.5e-140 469.1 0.1 1.8e-140 468.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Transposase_1 PF01359.18 CDS25335.1 - 1e-18 66.9 0.2 1.4e-17 63.2 0.0 2.5 2 0 0 2 2 2 1 Transposase (partial DDE domain) Glyco_hydro_127 PF07944.12 CDS25335.1 - 0.031 12.8 0.0 0.29 9.6 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 FHA PF00498.26 CDS25336.1 - 3.3e-09 37.0 0.5 9.3e-09 35.5 0.5 1.9 1 0 0 1 1 1 1 FHA domain ArfGap PF01412.18 CDS25337.1 - 2.4e-32 111.5 0.1 6e-32 110.2 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synuclein PF01387.17 CDS25337.1 - 0.018 15.2 1.6 0.041 14.1 1.6 1.6 1 0 0 1 1 1 0 Synuclein zinc_ribbon_2 PF13240.6 CDS25337.1 - 0.038 13.7 0.7 0.076 12.7 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 CDS25337.1 - 0.042 13.9 0.0 0.94 9.6 0.0 2.9 3 0 0 3 3 3 0 Ribosomal L37ae protein family ROS_MUCR PF05443.11 CDS25337.1 - 0.053 13.6 0.0 17 5.5 0.0 2.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Herpes_BLRF2 PF05812.12 CDS25338.1 - 0.042 14.0 1.7 0.088 12.9 1.7 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Serglycin PF04360.12 CDS25338.1 - 6.8 6.6 8.3 6.5 6.7 2.4 2.5 2 0 0 2 2 2 0 Serglycin tRNA_m1G_MT PF01746.21 CDS25339.1 - 7.3e-11 42.1 0.0 1.1e-10 41.6 0.0 1.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase AF0941-like PF14591.6 CDS25340.1 - 0.049 14.2 0.2 0.073 13.6 0.2 1.3 1 0 0 1 1 1 0 AF0941-like DUF5082 PF16888.5 CDS25340.1 - 0.067 13.5 0.2 0.1 12.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF725 PF05267.12 CDS25340.1 - 0.073 13.0 1.6 0.31 11.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF725) UPF0203 PF05254.12 CDS25340.1 - 0.076 13.3 2.2 0.86 9.9 1.6 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) MFS_1 PF07690.16 CDS25341.1 - 9.7e-27 93.8 46.3 7.3e-21 74.5 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YBD PF17725.1 CDS25342.1 - 1.8e-88 295.8 0.2 2.5e-88 295.4 0.2 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CDS25342.1 - 1.9e-26 91.9 0.1 4.2e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain CdiI PF07262.11 CDS25343.1 - 0.045 13.5 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 CDI immunity protein Cluap1 PF10234.9 CDS25344.1 - 2.1e-85 286.4 2.1 2.1e-85 286.4 2.1 1.5 2 0 0 2 2 2 1 Clusterin-associated protein-1 Ndc80_HEC PF03801.13 CDS25344.1 - 0.0075 15.9 0.2 1.2 8.8 0.0 2.5 1 1 1 2 2 2 2 HEC/Ndc80p family Atg14 PF10186.9 CDS25344.1 - 0.04 13.0 3.7 0.07 12.2 3.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spectrin_like PF18373.1 CDS25344.1 - 0.11 12.6 1.3 0.3 11.2 0.3 2.3 2 0 0 2 2 2 0 Spectrin like domain Spc7 PF08317.11 CDS25344.1 - 0.62 8.9 10.7 0.17 10.7 4.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.6 CDS25344.1 - 4.6 6.8 12.3 0.19 11.3 4.6 2.5 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Ig_3 PF13927.6 CDS25345.1 - 2e-13 50.7 2.2 0.00037 21.0 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 CDS25345.1 - 6.9e-10 39.0 0.0 0.029 14.6 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 CDS25345.1 - 1.3e-07 31.8 0.0 0.2 12.0 0.0 5.0 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 CDS25345.1 - 1.3e-06 28.5 0.0 2.1 8.6 0.0 5.1 4 1 0 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.16 CDS25345.1 - 2.5e-05 24.3 0.0 0.27 11.3 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_5 PF16681.5 CDS25345.1 - 0.0056 17.0 0.1 1.4 9.4 0.1 3.7 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Sec62 PF03839.16 CDS25346.1 - 0.028 14.0 0.7 0.042 13.4 0.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase_Tyr PF07714.17 CDS25347.1 - 1.2e-78 264.0 0.0 1.4e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25347.1 - 2.9e-40 138.3 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CDS25347.1 - 0.0021 17.4 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS25347.1 - 0.0087 16.0 0.0 0.13 12.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RT_RNaseH PF17917.1 CDS25349.1 - 7.1e-17 61.6 0.1 1.1e-16 61.0 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS25349.1 - 2.9e-11 43.3 0.1 5.2e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Clathrin_lg_ch PF01086.17 CDS25350.1 - 1.7e-24 87.1 13.9 3.8e-24 86.0 13.9 1.6 1 1 0 1 1 1 1 Clathrin light chain UPF0061 PF02696.14 CDS25350.1 - 0.27 9.9 6.4 2 7.1 6.4 1.9 1 1 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Recep_L_domain PF01030.24 CDS25351.1 - 0.0012 18.9 1.9 0.0058 16.7 1.9 1.9 1 1 0 1 1 1 1 Receptor L domain RNA_pol_Rpb2_6 PF00562.28 CDS25352.1 - 1.9e-115 386.1 0.0 2.7e-115 385.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDS25352.1 - 2.8e-46 157.6 0.0 4.1e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CDS25352.1 - 5.2e-29 100.5 2.3 6.6e-29 100.2 0.2 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CDS25352.1 - 1.2e-22 80.0 0.6 3.4e-22 78.5 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CDS25352.1 - 3.4e-22 78.4 0.1 7.4e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CDS25352.1 - 3.9e-22 78.8 0.1 7.2e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CDS25352.1 - 1.3e-07 32.1 0.6 3.8e-07 30.6 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Transposase_1 PF01359.18 CDS25355.1 - 6.6e-13 48.3 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) UBA_4 PF14555.6 CDS25356.1 - 1e-08 34.8 1.0 2.4e-08 33.7 1.0 1.6 1 0 0 1 1 1 1 UBA-like domain Exo_endo_phos PF03372.23 CDS25356.1 - 0.0042 16.6 0.0 0.016 14.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1198 PF06711.11 CDS25356.1 - 0.054 13.5 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Acyltransferase PF01553.21 CDS25357.1 - 1.6e-10 40.7 0.0 2.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sod_Fe_C PF02777.18 CDS25358.1 - 2.1e-37 127.4 0.0 8.6e-37 125.4 0.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDS25358.1 - 1.8e-32 111.7 1.3 2.7e-32 111.1 1.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_gyraseB PF00204.25 CDS25358.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase B GFRP PF06399.13 CDS25359.1 - 0.024 14.5 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF629 PF04780.12 CDS25359.1 - 0.057 12.0 1.4 0.089 11.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-Mss51 PF13824.6 CDS25359.1 - 0.15 12.2 10.1 0.17 12.0 3.5 3.0 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.10 CDS25359.1 - 0.99 9.6 5.7 3.5 7.8 3.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-DBF PF07535.12 CDS25359.1 - 2.7 8.2 9.1 5.9 7.1 9.1 1.5 1 0 0 1 1 1 0 DBF zinc finger Aldedh PF00171.22 CDS25360.1 - 5.3e-79 265.9 0.0 6.4e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TFIIE_beta PF02186.15 CDS25361.1 - 1.8e-17 63.4 0.5 6.7e-17 61.5 0.5 2.1 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 CDS25361.1 - 3.8e-06 26.5 0.2 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 Coprogen_oxidas PF01218.18 CDS25361.1 - 0.00023 20.0 0.0 0.00035 19.4 0.0 1.3 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PhoQ_Sensor PF08918.10 CDS25361.1 - 0.0087 15.9 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 PhoQ Sensor DUF4132 PF13569.6 CDS25361.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) TFIIE_beta PF02186.15 CDS25362.1 - 1.2e-15 57.5 0.0 9e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 CDS25362.1 - 0.00064 19.4 0.0 0.0035 17.0 0.0 2.3 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 Viral_DNA_Zn_bi PF03728.13 CDS25362.1 - 0.053 14.1 0.1 0.2 12.2 0.0 1.9 2 0 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain Coprogen_oxidas PF01218.18 CDS25362.1 - 0.083 11.6 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase Dcc1 PF09724.9 CDS25363.1 - 1.1e-60 205.8 0.0 1.4e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 LRR_1 PF00560.33 CDS25363.1 - 0.031 14.8 3.9 48 5.1 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Rad10 PF03834.14 CDS25363.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) LRR_6 PF13516.6 CDS25363.1 - 0.71 10.1 5.6 25 5.3 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DUF758 PF05527.11 CDS25364.1 - 2.7e-46 157.8 1.0 3.1e-46 157.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Umbravirus_LDM PF04817.12 CDS25364.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.3 1 1 0 1 1 1 0 Umbravirus long distance movement (LDM) family ObR_Ig PF18589.1 CDS25364.1 - 0.14 12.5 2.2 0.31 11.5 2.2 1.5 1 0 0 1 1 1 0 Obesity receptor immunoglobulin like domain zf-C2H2 PF00096.26 CDS25365.1 - 1.7e-13 50.2 25.7 0.00021 21.6 1.6 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS25365.1 - 4.8e-10 39.4 10.6 2e-07 31.1 2.9 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS25365.1 - 2.2e-06 28.0 21.4 0.068 14.0 2.6 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS25365.1 - 0.031 14.3 7.1 0.042 13.8 2.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS25365.1 - 0.14 12.4 5.5 1.5 9.2 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CDS25365.1 - 2 8.5 4.4 5.7 7.1 4.4 1.8 1 0 0 1 1 1 0 Aberrant zinc-finger Transposase_1 PF01359.18 CDS25366.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Transposase (partial DDE domain) zf-RING_9 PF13901.6 CDS25367.1 - 3.6e-26 92.4 8.8 3.6e-26 92.4 8.8 2.5 2 1 0 2 2 2 1 Putative zinc-RING and/or ribbon Geminin PF07412.12 CDS25368.1 - 1.4e-08 34.7 3.1 4.8e-08 33.0 3.1 1.7 1 1 0 1 1 1 1 Geminin EAP30 PF04157.16 CDS25368.1 - 0.0016 17.8 0.1 0.002 17.4 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Cnn_1N PF07989.11 CDS25368.1 - 0.097 12.8 1.2 0.57 10.4 0.2 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-CHC2 PF01807.20 CDS25368.1 - 0.11 12.3 0.2 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 CHC2 zinc finger Nucleoside_tran PF01733.18 CDS25369.1 - 4.4e-53 180.7 17.2 9.9e-53 179.5 17.2 1.6 1 1 0 1 1 1 1 Nucleoside transporter SPRY PF00622.28 CDS25370.1 - 1.8e-27 95.8 0.2 1.4e-16 60.7 0.3 3.2 2 1 0 2 2 2 2 SPRY domain FERM_C PF09380.10 CDS25370.1 - 2.8e-19 69.3 0.0 6.8e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDS25370.1 - 1e-16 61.4 0.0 5.1e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDS25370.1 - 1.2e-12 47.5 0.1 2.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain CAF1A PF12253.8 CDS25371.2 - 3.5e-25 88.0 7.8 3.5e-25 88.0 7.8 4.8 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A BRX_assoc PF16627.5 CDS25372.1 - 0.011 15.9 1.1 0.24 11.5 0.4 2.7 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Rad50_zn_hook PF04423.14 CDS25372.1 - 0.013 15.3 1.0 0.03 14.2 1.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif RNF220 PF15926.5 CDS25372.1 - 0.063 12.9 5.6 0.41 10.2 5.6 2.1 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 CDS25372.1 - 0.07 13.4 0.4 0.22 11.9 0.2 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Glycos_transf_2 PF00535.26 CDS25373.1 - 6.7e-28 97.6 0.0 1e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDS25373.1 - 7.4e-11 42.4 2.6 1.6e-10 41.4 2.6 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDS25373.1 - 0.00028 20.5 0.2 0.00064 19.3 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CDS25373.1 - 0.0043 16.6 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RT_RNaseH_2 PF17919.1 CDS25375.1 - 2.6e-27 94.8 0.3 3.6e-27 94.3 0.3 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS25375.1 - 3.2e-26 91.6 0.1 5.2e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mgr1 PF08602.10 CDS25375.1 - 0.073 11.9 0.3 0.088 11.6 0.3 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit CAF1C_H4-bd PF12265.8 CDS25376.1 - 3.4e-27 94.5 2.2 7.2e-27 93.4 0.4 2.5 4 0 0 4 4 4 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDS25376.1 - 2.8e-25 88.1 13.7 2.2e-06 28.3 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25376.1 - 6.3e-07 29.6 1.0 0.043 14.1 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain FOXP-CC PF16159.5 CDS25378.1 - 0.024 15.3 10.7 1.3 9.8 0.5 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF4729 PF15866.5 CDS25378.1 - 0.089 12.1 0.3 0.089 12.1 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4729) zf-C2H2_aberr PF17017.5 CDS25378.1 - 0.26 11.4 5.4 0.37 10.9 2.9 2.3 2 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 CDS25378.1 - 0.5 10.9 5.8 1.6 9.3 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 CDS25378.1 - 1.2 9.8 11.1 0.34 11.5 3.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDS25378.1 - 3.5 8.0 6.6 26 5.2 0.2 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Tim29 PF10171.9 CDS25380.1 - 4.6e-26 91.3 0.0 5.5e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Translocase of the Inner Mitochondrial membrane 29 TFIIIC_sub6 PF10419.9 CDS25380.1 - 3.2e-15 55.8 0.0 5.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain RhoGAP PF00620.27 CDS25381.2 - 2.2e-17 63.3 0.1 2.5e-16 59.8 0.1 2.3 1 1 0 1 1 1 1 RhoGAP domain DUF1912 PF08930.10 CDS25381.2 - 0.17 12.0 0.0 0.54 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) PAXNEB PF05625.11 CDS25382.1 - 4.4e-56 190.6 0.0 5.9e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Adap_comp_sub PF00928.21 CDS25383.1 - 2.3e-68 230.4 0.0 3.2e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDS25383.1 - 8.5e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain I-set PF07679.16 CDS25384.2 - 1.4e-296 957.7 0.0 1.7e-21 76.0 0.0 21.5 21 0 0 21 21 21 20 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS25384.2 - 5.8e-212 686.9 14.7 1.2e-15 57.8 0.1 21.5 21 0 0 21 21 21 20 Immunoglobulin domain Ig_2 PF13895.6 CDS25384.2 - 2.2e-110 361.2 7.8 8.9e-10 38.8 0.0 19.5 19 0 0 19 19 19 14 Immunoglobulin domain ig PF00047.25 CDS25384.2 - 7.4e-80 263.2 0.0 2.7e-09 37.1 0.0 19.7 19 0 0 19 19 19 14 Immunoglobulin domain V-set PF07686.17 CDS25384.2 - 7.1e-45 151.7 5.3 5.1e-06 26.6 0.1 20.3 16 6 0 16 16 16 7 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS25384.2 - 3.7e-27 94.2 22.8 0.019 15.0 0.1 17.0 20 0 0 20 20 18 7 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS25384.2 - 4.3e-09 35.8 0.1 0.3 10.7 0.0 6.7 7 0 0 7 7 7 2 Immunoglobulin domain Izumo-Ig PF16706.5 CDS25384.2 - 3.6e-08 33.3 0.2 4.5 7.4 0.0 8.1 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Spectrin PF00435.21 CDS25384.2 - 2.2e-06 28.1 33.8 1.1e-05 25.9 0.4 6.4 6 1 1 7 7 6 3 Spectrin repeat V-set_CD47 PF08204.11 CDS25384.2 - 0.00024 21.1 0.0 3.2 7.7 0.0 5.4 5 0 0 5 5 5 1 CD47 immunoglobulin-like domain Suppressor_APC PF11414.8 CDS25384.2 - 0.24 11.5 2.8 2.2 8.4 0.1 3.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Tub PF01167.18 CDS25385.2 - 1.3e-50 172.5 0.0 4.3e-50 170.7 0.0 1.9 1 1 0 1 1 1 1 Tub family ThiP_synth PF10120.9 CDS25385.2 - 0.064 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine-phosphate synthase Uso1_p115_head PF04869.14 CDS25386.1 - 1.3e-44 152.7 2.0 1.2e-27 96.9 0.0 3.9 4 0 0 4 4 4 2 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 CDS25386.1 - 5.2e-19 67.9 1.6 5.2e-19 67.9 1.6 2.7 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Uso1_p115_C PF04871.13 CDS25386.1 - 4.1e-06 27.2 14.0 4.1e-06 27.2 14.0 1.7 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region SseC PF04888.12 CDS25386.1 - 0.0067 16.1 0.7 0.012 15.2 0.7 1.5 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Matrilin_ccoil PF10393.9 CDS25386.1 - 0.46 10.4 3.4 1.8 8.5 0.9 2.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin YabA PF06156.13 CDS25386.1 - 0.52 11.0 4.0 1.8 9.2 4.0 1.9 1 0 0 1 1 1 0 Initiation control protein YabA MAD PF05557.13 CDS25386.1 - 1.3 7.2 17.2 2.3 6.5 17.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein UPF0242 PF06785.11 CDS25386.1 - 3.6 7.6 17.9 6.1 6.9 8.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CDS25386.1 - 5.3 6.5 12.9 11 5.4 12.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CDS25386.1 - 6.9 5.9 15.2 12 5.1 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 CDS25387.1 - 9.1e-19 67.5 0.1 2e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ROF PF07073.12 CDS25389.1 - 0.57 10.4 5.1 0.2 11.8 1.5 2.1 3 0 0 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) Hyd_WA PF06462.12 CDS25390.1 - 9.8e-33 111.8 17.2 1.2e-08 34.8 0.1 7.7 7 0 0 7 7 7 5 Propeller GLTP PF08718.11 CDS25391.1 - 7.2e-34 117.2 0.0 9.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Viral_NABP PF05515.11 CDS25392.1 - 0.0085 16.0 1.5 0.014 15.2 1.5 1.3 1 0 0 1 1 1 1 Viral nucleic acid binding Exostosin PF03016.15 CDS25392.1 - 0.1 11.8 0.5 0.13 11.4 0.5 1.1 1 0 0 1 1 1 0 Exostosin family BIR PF00653.21 CDS25393.1 - 4e-08 33.8 0.1 7.7e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DUF1190 PF06693.11 CDS25393.1 - 0.025 15.0 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) AIF-MLS PF14962.6 CDS25393.1 - 0.069 13.1 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence COX5B PF01215.19 CDS25395.2 - 1e-06 28.4 0.0 2.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb CCAP PF11105.8 CDS25395.2 - 0.038 14.0 1.2 0.076 13.0 1.2 1.4 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Xpo1 PF08389.12 CDS25397.1 - 1.4e-15 57.6 6.9 1.7e-15 57.3 0.1 3.9 4 1 0 4 4 4 1 Exportin 1-like protein RIX1 PF08167.12 CDS25397.1 - 0.058 13.1 4.8 0.34 10.6 0.1 3.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 CDS25397.1 - 0.093 12.6 1.0 1.9 8.4 0.1 3.2 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal 60KD_IMP PF02096.20 CDS25398.2 - 2.5e-07 30.7 0.0 4.7e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein Nop PF01798.18 CDS25400.1 - 5.7e-26 91.4 1.1 3.1e-11 43.2 3.7 3.3 2 1 0 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDS25400.1 - 2.5e-08 34.2 0.1 7.5e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RVP PF00077.20 CDS25401.1 - 5.1e-05 23.5 0.0 6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDS25401.1 - 5.3e-05 23.7 0.0 5.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS25401.1 - 0.00044 20.8 0.0 0.00048 20.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DTHCT PF08070.11 CDS25402.2 - 0.036 14.8 13.3 0.04 14.7 3.9 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region SR-25 PF10500.9 CDS25402.2 - 3 7.4 24.7 0.091 12.4 6.2 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Piwi PF02171.17 CDS25403.1 - 3.7e-80 269.4 0.0 5.3e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CDS25403.1 - 5.1e-13 49.0 0.1 1.2e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CDS25403.1 - 2e-09 38.2 0.0 6.2e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDS25403.1 - 3.4e-05 23.4 0.0 8.5e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain HECT PF00632.25 CDS25404.1 - 4.7e-48 164.3 0.1 4.9e-48 164.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) S36_mt PF10937.8 CDS25404.1 - 0.0042 18.7 0.1 2.1 9.9 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein S36, mitochondrial Methyltransf_4 PF02390.17 CDS25405.2 - 6.8e-48 162.4 0.0 8.8e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CDS25405.2 - 4.7e-06 27.2 0.0 8.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS25405.2 - 0.0006 20.4 0.0 0.0029 18.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDS25405.2 - 0.00069 19.2 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CDS25405.2 - 0.00098 19.1 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS25405.2 - 0.0018 19.0 0.0 0.0044 17.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS25405.2 - 0.0042 16.9 0.0 0.0062 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS25405.2 - 0.086 12.7 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CDS25405.2 - 0.09 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SNARE PF05739.19 CDS25406.1 - 1.3e-09 37.9 0.1 2.7e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 SNARE domain RPN6_N PF18055.1 CDS25406.1 - 0.078 13.3 2.5 0.38 11.1 0.4 2.9 2 2 2 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain Mitoc_L55 PF09776.9 CDS25407.1 - 1.6e-25 89.1 0.0 1.7e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 GalP_UDP_transf PF01087.22 CDS25408.1 - 2.5e-55 187.7 0.2 8.1e-55 186.1 0.1 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CDS25408.1 - 2.7e-48 163.9 1.3 4.8e-48 163.0 0.1 2.0 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Prefoldin_2 PF01920.20 CDS25408.1 - 0.0002 21.3 0.8 0.00045 20.1 0.8 1.5 1 0 0 1 1 1 1 Prefoldin subunit Pkinase PF00069.25 CDS25409.1 - 2.1e-27 96.1 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25409.1 - 2.7e-15 56.4 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS25409.1 - 2.3e-09 36.6 0.0 3.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS25409.1 - 0.00018 21.5 0.2 0.6 10.0 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS25409.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GRAM PF02893.20 CDS25410.1 - 8.2e-10 38.6 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 CDS25410.1 - 0.043 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 T5orf172 PF10544.9 CDS25411.1 - 0.017 15.6 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 T5orf172 domain Hpr_kinase_N PF02603.16 CDS25411.1 - 0.027 14.5 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase N terminus RCC1 PF00415.18 CDS25412.1 - 5.6e-43 145.3 8.9 7.7e-12 45.7 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDS25412.1 - 1.4e-32 110.7 24.8 2.5e-11 43.1 0.3 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF3456 PF11938.8 CDS25413.1 - 1.8e-33 116.2 1.1 2.5e-33 115.8 1.1 1.1 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP HD_3 PF13023.6 CDS25414.1 - 3.5e-46 157.1 0.0 4.2e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CDS25414.1 - 6e-12 45.7 0.0 7.5e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CDS25414.1 - 4.7e-05 23.6 0.0 7.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 HD domain Hanta_G1 PF01567.16 CDS25414.1 - 0.19 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 RIC1 PF07064.13 CDS25415.1 - 5.5e-85 284.8 0.8 9.8e-85 284.0 0.8 1.4 1 0 0 1 1 1 1 RIC1 IBN_N PF03810.19 CDS25415.1 - 0.06 13.3 0.2 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain SET PF00856.28 CDS25416.1 - 1.4e-08 35.3 2.0 6.4e-08 33.2 2.0 2.2 1 1 0 1 1 1 1 SET domain Exo_endo_phos_2 PF14529.6 CDS25417.2 - 1.1e-11 44.6 0.0 2.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PP1_inhibitor PF05361.12 CDS25418.1 - 0.15 12.0 0.4 0.21 11.6 0.4 1.2 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Neur_chan_memb PF02932.16 CDS25419.1 - 6.7 6.7 6.7 8.7 6.3 6.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_M22 PF00814.25 CDS25421.1 - 1.2e-74 251.4 0.0 1.7e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family EF-hand_1 PF00036.32 CDS25422.1 - 8.6e-15 53.1 3.7 3.4e-09 35.6 0.6 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS25422.1 - 2.7e-14 53.4 1.3 3.3e-14 53.1 1.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS25422.1 - 2.5e-11 43.2 3.2 2.8e-11 43.1 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS25422.1 - 1.3e-10 40.3 1.6 0.00053 19.7 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 CDS25422.1 - 3e-07 30.7 0.0 4.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CDS25422.1 - 3.5e-05 23.1 5.9 0.001 18.4 0.8 3.0 2 1 1 3 3 3 2 EF hand SUB1_ProdP9 PF18213.1 CDS25422.1 - 0.0031 17.3 1.0 0.0045 16.8 0.7 1.4 1 1 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 CDS25422.1 - 0.033 14.5 0.1 0.04 14.3 0.1 1.2 1 0 0 1 1 1 0 EF-hand domain SurA_N_3 PF13624.6 CDS25422.1 - 0.034 13.9 0.5 0.037 13.8 0.5 1.1 1 0 0 1 1 1 0 SurA N-terminal domain DUF3911 PF13050.6 CDS25422.1 - 0.045 13.9 0.3 0.057 13.5 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3911) SurA_N_2 PF13623.6 CDS25422.1 - 0.05 13.5 0.5 0.081 12.8 0.5 1.6 1 1 0 1 1 1 0 SurA N-terminal domain Dockerin_1 PF00404.18 CDS25422.1 - 0.058 13.6 0.3 0.071 13.3 0.3 1.3 1 0 0 1 1 1 0 Dockerin type I domain Gp-FAR-1 PF05823.12 CDS25422.1 - 0.063 13.6 0.8 0.11 12.9 0.3 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SF3b1 PF08920.10 CDS25423.1 - 4.1e-38 130.5 34.4 4.6e-36 123.9 14.7 5.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 CDS25423.1 - 1.8e-09 37.0 5.6 0.36 11.2 0.1 7.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDS25423.1 - 1.9e-09 37.8 2.1 0.076 13.4 0.0 7.2 6 2 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 CDS25423.1 - 2e-08 34.5 5.7 1 9.9 0.0 7.5 8 1 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDS25423.1 - 6e-05 23.6 0.9 2.3 8.9 0.0 4.7 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDS25423.1 - 7.2e-05 22.9 7.1 7.7 6.5 0.0 6.6 6 2 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 CDS25423.1 - 0.0033 17.1 0.3 0.79 9.3 0.0 3.9 3 2 1 4 4 4 1 NUC173 domain CLASP_N PF12348.8 CDS25423.1 - 0.0042 16.7 0.8 2 7.9 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 CDS25423.1 - 0.0061 16.5 2.5 8 6.3 0.0 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) IFRD PF05004.13 CDS25423.1 - 0.008 15.3 0.0 8.8 5.3 0.0 3.4 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 CDS25423.1 - 0.14 12.1 0.1 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Cmc1 PF08583.10 CDS25425.1 - 2.3e-05 24.3 4.3 3.1e-05 23.9 4.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GerD PF17898.1 CDS25425.1 - 0.17 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Spore germination GerD central core domain Sortilin-Vps10 PF15902.5 CDS25426.1 - 1.3e-67 228.5 0.0 1.2e-41 143.0 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CDS25426.1 - 1.3e-29 103.7 0.9 2.1e-29 103.0 0.9 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CDS25426.1 - 2.3e-10 38.8 17.8 1.2 9.4 0.1 8.1 7 0 0 7 7 7 5 BNR/Asp-box repeat BNR_2 PF13088.6 CDS25426.1 - 2.4e-05 23.8 1.4 0.0043 16.4 0.2 3.8 3 1 0 4 4 4 1 BNR repeat-like domain BNR_6 PF15899.5 CDS25426.1 - 0.037 14.1 0.6 3.2 8.1 0.0 3.9 4 0 0 4 4 4 0 BNR-Asp box repeat Sec61_beta PF03911.16 CDS25427.1 - 1.8e-15 56.7 0.2 2.4e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Spindle_Spc25 PF08234.12 CDS25428.1 - 3.8e-14 52.7 1.1 5.7e-14 52.1 0.1 1.8 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 CDS25428.1 - 1.1e-05 24.5 0.8 2e-05 23.7 0.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF444 PF04285.12 CDS25428.1 - 0.044 12.9 1.0 0.066 12.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) BAR PF03114.18 CDS25428.1 - 0.051 13.2 2.9 0.043 13.4 1.5 1.6 2 0 0 2 2 2 0 BAR domain BST2 PF16716.5 CDS25428.1 - 0.076 13.6 4.1 0.085 13.5 2.7 1.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ZapB PF06005.12 CDS25428.1 - 0.082 13.4 5.5 0.2 12.2 5.5 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 CDS25428.1 - 0.11 12.3 4.7 0.1 12.4 1.4 2.4 1 1 1 2 2 2 0 Septum formation initiator TSP_1 PF00090.19 CDS25429.1 - 1.2e-09 38.2 31.0 9.4e-07 29.0 4.8 4.6 4 1 0 4 4 4 2 Thrombospondin type 1 domain Ig_3 PF13927.6 CDS25429.1 - 1.4e-05 25.6 0.4 3.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDS25429.1 - 0.0059 16.7 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS25429.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin I-set domain Homeodomain PF00046.29 CDS25430.1 - 2.9e-18 65.5 2.8 4.9e-18 64.7 2.8 1.4 1 0 0 1 1 1 1 Homeodomain Auxin_canalis PF05703.11 CDS25430.1 - 0.0015 18.6 0.2 0.002 18.1 0.2 1.2 1 0 0 1 1 1 1 Auxin canalisation Homez PF11569.8 CDS25430.1 - 0.0053 16.2 1.7 0.0079 15.6 0.2 2.2 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CDS25430.1 - 0.012 15.5 0.6 0.023 14.6 0.6 1.5 1 0 0 1 1 1 0 Homeobox KN domain MAGE_N PF12440.8 CDS25430.1 - 0.71 10.6 7.0 1.5 9.5 7.0 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF717 PF05338.12 CDS25431.1 - 0.16 12.1 11.2 0.9 9.7 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF717) CagY_M PF07337.11 CDS25431.1 - 3.6 7.3 6.9 48 3.7 0.7 4.1 4 0 0 4 4 4 0 DC-EC Repeat DSPc PF00782.20 CDS25432.1 - 1.7e-36 125.0 0.0 3.3e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS25432.1 - 0.0014 18.2 0.2 0.0022 17.6 0.2 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDS25432.1 - 0.0021 18.2 0.1 0.0053 16.9 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate ADH_zinc_N PF00107.26 CDS25432.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GNT-I PF03071.15 CDS25433.1 - 2.4e-110 369.3 0.2 3.7e-110 368.7 0.2 1.2 1 0 0 1 1 1 1 GNT-I family ArfGap PF01412.18 CDS25433.1 - 1e-30 106.2 0.0 2.8e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CDS25433.1 - 1.7e-12 47.6 0.2 3.6e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CDS25433.1 - 2.3e-12 47.3 0.2 7.2e-12 45.7 0.2 1.9 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 CDS25433.1 - 1.6e-10 41.4 0.8 5.6e-10 39.7 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS25433.1 - 5.4e-10 39.3 2.5 2.1e-06 27.9 0.3 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS25433.1 - 1.1e-08 35.5 1.2 5.3e-08 33.2 0.2 2.7 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDS25433.1 - 5.3e-06 26.6 4.2 0.094 13.2 0.2 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CDS25433.1 - 4.9e-05 23.4 4.6 0.011 16.2 0.3 3.5 3 0 0 3 3 2 2 Ankyrin repeat PH_11 PF15413.6 CDS25433.1 - 0.0061 17.0 1.1 0.028 14.8 1.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CDS25433.1 - 0.052 13.9 0.2 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 CDS25433.1 - 0.061 13.6 2.3 2.4 8.5 0.2 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain PrmA PF06325.13 CDS25436.1 - 5.2e-11 42.5 0.1 9.1e-11 41.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDS25436.1 - 6.4e-11 42.1 0.0 9.7e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CDS25436.1 - 1.7e-08 34.4 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDS25436.1 - 5.1e-07 29.5 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDS25436.1 - 1.2e-06 29.1 0.0 2.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS25436.1 - 0.0002 22.1 0.0 0.0005 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS25436.1 - 0.00022 21.8 0.0 0.00048 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDS25436.1 - 0.00051 19.8 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 CDS25436.1 - 0.025 14.4 0.0 0.062 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 CDS25436.1 - 0.059 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_9 PF08003.11 CDS25436.1 - 0.067 12.1 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ribosomal_L2_C PF03947.18 CDS25437.1 - 1.3e-17 64.2 0.0 3.9e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDS25437.1 - 1.3e-10 41.1 0.0 3.8e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain ThiF PF00899.21 CDS25439.1 - 9e-53 179.1 0.0 1.3e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CDS25439.1 - 8.8e-17 61.0 0.5 1.3e-16 60.5 0.5 1.2 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 CDS25439.1 - 9e-05 23.0 0.2 0.00017 22.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain OATP PF03137.20 CDS25440.1 - 7.1e-143 476.8 16.2 1.7e-77 261.0 3.2 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDS25440.1 - 6e-13 48.4 31.7 1.7e-09 37.1 17.2 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.15 CDS25440.1 - 0.016 15.4 7.9 0.041 14.0 7.9 1.8 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Sec6 PF06046.13 CDS25441.1 - 2e-78 264.2 0.1 2.6e-78 263.9 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.14 CDS25441.1 - 1.8e-05 24.7 0.9 5e-05 23.2 0.9 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain TBCC_N PF16752.5 CDS25441.1 - 0.56 10.7 7.5 0.55 10.7 2.5 3.1 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 CDS25441.1 - 1.3 9.0 6.9 2.9 7.9 3.0 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 CDS25442.1 - 0.016 15.4 2.6 0.016 15.4 2.6 3.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 CDS25442.1 - 0.064 13.3 0.9 0.57 10.3 1.5 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 CDS25442.1 - 0.081 13.5 3.1 3.1 8.4 1.8 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF641 PF04859.12 CDS25442.1 - 0.15 12.4 3.5 0.38 11.1 3.5 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CDS25442.1 - 0.24 10.3 12.0 0.023 13.6 7.5 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 CDS25442.1 - 0.53 10.7 8.9 0.12 12.9 5.1 1.9 2 1 0 2 2 2 0 Fez1 LemA PF04011.12 CDS25442.1 - 0.86 9.4 7.5 0.42 10.5 0.4 2.7 2 1 1 3 3 3 0 LemA family CC2-LZ PF16516.5 CDS25442.1 - 1 9.8 5.5 1.1 9.7 1.7 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PilJ PF13675.6 CDS25442.1 - 1.7 8.7 4.1 5.8 7.0 0.9 2.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ABC_tran_CTD PF16326.5 CDS25442.1 - 5.9 7.2 10.9 0.77 10.1 5.8 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Asp PF00026.23 CDS25443.1 - 1.5e-111 372.8 0.0 1.8e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDS25443.1 - 4.4e-13 49.8 0.4 3e-11 43.9 0.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDS25443.1 - 5.3e-05 23.0 0.0 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDS25443.1 - 0.00037 21.1 0.0 0.17 12.6 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease MCC-bdg_PDZ PF10506.9 CDS25444.1 - 1.3e-12 47.6 3.8 1.3e-12 47.6 3.8 3.9 3 2 0 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Tropomyosin PF00261.20 CDS25444.1 - 0.041 13.2 14.7 0.0092 15.4 3.8 2.5 2 0 0 2 2 2 0 Tropomyosin Gp-FAR-1 PF05823.12 CDS25444.1 - 0.14 12.6 0.8 0.97 9.8 0.5 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1043 PF06295.12 CDS25444.1 - 0.26 11.3 17.2 0.1 12.6 2.9 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) Phage_GP20 PF06810.11 CDS25444.1 - 0.59 9.9 6.7 4 7.2 2.1 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 ZapD PF07072.11 CDS25444.1 - 0.82 9.4 13.1 3.9 7.2 1.5 2.4 2 0 0 2 2 2 0 Cell division protein Jnk-SapK_ap_N PF09744.9 CDS25444.1 - 4.1 7.6 20.5 1.3 9.2 3.5 3.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Med21 PF11221.8 CDS25444.1 - 6 7.1 16.5 0.23 11.7 3.0 3.0 3 0 0 3 3 3 0 Subunit 21 of Mediator complex MIP-T3_C PF17749.1 CDS25444.1 - 6.5 6.7 9.8 2.1 8.3 2.5 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region TolA_bind_tri PF16331.5 CDS25444.1 - 6.5 6.9 16.3 3 8.0 3.5 3.1 2 1 0 2 2 2 0 TolA binding protein trimerisation Hist_deacetyl PF00850.19 CDS25445.1 - 5.7e-78 262.5 0.0 1.6e-74 251.2 0.0 2.3 2 0 0 2 2 2 2 Histone deacetylase domain Hist_deacetyl PF00850.19 CDS25446.1 - 4.4e-110 368.0 2.0 2.5e-56 191.4 0.1 3.2 2 1 1 3 3 3 3 Histone deacetylase domain zf-UBP PF02148.19 CDS25446.1 - 9.7e-20 70.7 10.6 2.6e-19 69.3 10.6 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CDS25446.1 - 0.016 15.0 0.5 0.016 15.0 0.5 2.1 2 0 0 2 2 2 0 Variant UBP zinc finger PHO4 PF01384.20 CDS25447.1 - 2.2e-120 401.7 19.4 2.7e-120 401.5 19.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 CDS25448.1 - 8.8e-121 403.1 20.6 1.1e-120 402.8 20.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 CDS25449.1 - 1.7e-119 398.9 16.5 2.1e-119 398.5 16.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF4574 PF15141.6 CDS25449.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PHO4 PF01384.20 CDS25450.1 - 9.9e-125 416.0 13.4 1.2e-124 415.7 13.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family LapA_dom PF06305.11 CDS25450.1 - 0.0022 17.8 1.0 0.0022 17.8 1.0 5.0 5 1 1 6 6 6 1 Lipopolysaccharide assembly protein A domain PHO4 PF01384.20 CDS25451.1 - 6.2e-123 410.1 15.1 8.1e-123 409.8 15.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family DoxX_2 PF13564.6 CDS25451.1 - 0.0046 17.0 1.5 0.0046 17.0 1.5 3.1 3 1 0 3 3 3 1 DoxX-like family Pkinase PF00069.25 CDS25452.2 - 8.4e-62 208.9 0.0 1.1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25452.2 - 4.4e-42 144.1 0.0 6.8e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CDS25452.2 - 4.8e-12 45.9 0.0 1.1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 CDS25452.2 - 0.00022 20.6 0.0 0.00047 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDS25452.2 - 0.0087 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CDS25452.2 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDS25452.2 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS25452.2 - 0.021 13.8 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Na_K-ATPase PF00287.18 CDS25453.1 - 8.9e-26 90.7 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain THAP PF05485.12 CDS25454.1 - 8e-17 62.0 2.1 1.7e-16 60.9 0.5 2.3 2 0 0 2 2 2 1 THAP domain P66_CC PF16563.5 CDS25454.1 - 8e-07 28.6 0.2 8e-07 28.6 0.2 2.8 3 0 0 3 3 3 1 Coiled-coil and interaction region of P66A and P66B with MBD2 GATA PF00320.27 CDS25454.1 - 0.0005 19.6 1.3 0.0012 18.4 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger LysM PF01476.20 CDS25455.1 - 0.13 12.3 0.6 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 LysM domain Na_K-ATPase PF00287.18 CDS25456.1 - 1e-36 126.6 0.8 1.4e-36 126.2 0.8 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain tRNA-synt_1g PF09334.11 CDS25457.2 - 2.9e-145 483.9 0.3 3.8e-145 483.5 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDS25457.2 - 4.4e-08 33.2 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CDS25457.2 - 1.1e-07 30.6 1.8 0.0012 17.3 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) TackOD1 PF18551.1 CDS25457.2 - 0.045 13.4 1.3 0.091 12.4 1.3 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 CDS25457.2 - 0.53 10.3 6.1 1.3 9.0 6.1 1.7 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 CDS25457.2 - 1.9 8.6 8.6 3 7.9 6.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HC5 PF06221.13 CDS25457.2 - 3.6 7.6 7.9 2.4 8.2 0.9 2.6 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type DHHC PF01529.20 CDS25458.1 - 1.7e-23 83.2 10.9 1.7e-23 83.2 10.9 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CDS25458.1 - 2.2e-20 73.0 0.8 2.4e-10 40.9 0.1 3.6 1 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25458.1 - 5.7e-19 68.2 1.1 1.3e-08 35.2 0.0 4.8 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS25458.1 - 1.3e-15 55.9 2.5 0.017 15.6 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CDS25458.1 - 2.5e-12 46.6 2.5 0.011 16.1 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CDS25458.1 - 3.4e-12 46.3 2.7 0.012 15.9 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) TBP PF00352.21 CDS25459.1 - 2.5e-68 226.1 1.2 5.7e-34 115.9 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDS25459.1 - 5.1e-06 26.5 0.3 0.18 12.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) GST_C_4 PF14834.6 CDS25459.1 - 0.18 12.2 0.1 1 9.7 0.1 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Peptidase_M1 PF01433.20 CDS25460.1 - 2.7e-40 138.3 0.0 4.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CDS25460.1 - 7e-27 93.8 0.2 2e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CDS25460.1 - 1.5e-25 90.4 0.1 2.3e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CDS25461.1 - 1.9e-41 142.1 0.0 2.9e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CDS25461.1 - 5.1e-31 107.1 0.6 3.4e-30 104.4 0.0 2.4 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CDS25461.1 - 2.9e-25 89.5 0.3 4.8e-25 88.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 CDS25461.1 - 0.00075 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ribosomal_L26 PF16906.5 CDS25462.1 - 9e-38 128.6 5.3 1.7e-37 127.7 5.3 1.5 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CDS25462.1 - 0.00073 19.4 2.0 0.0014 18.5 2.0 1.5 1 0 0 1 1 1 1 KOW motif Sugar_tr PF00083.24 CDS25463.1 - 7.9e-111 371.1 29.4 9.2e-111 370.9 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS25463.1 - 5.6e-20 71.6 45.1 8.5e-20 71.0 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CDS25463.1 - 0.023 15.2 4.3 0.023 15.2 4.3 2.5 2 1 0 2 2 2 0 Phage holin family 2 TPR_8 PF13181.6 CDS25464.1 - 1.8 9.0 3.3 10 6.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mucin PF01456.17 CDS25465.1 - 0.02 14.9 7.4 0.03 14.3 7.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CDS25465.1 - 0.14 10.3 6.1 0.19 9.9 6.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAM_2 PF07647.17 CDS25466.1 - 6.2e-25 87.1 0.3 2.5e-08 33.9 0.0 3.7 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS25466.1 - 3.4e-20 72.2 0.6 1.8e-09 37.9 0.0 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) CorA PF01544.18 CDS25466.1 - 0.19 11.0 0.6 0.35 10.1 0.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SID-1_RNA_chan PF13965.6 CDS25467.1 - 3.8e-211 702.7 28.5 7e-125 417.8 25.6 3.0 3 0 0 3 3 3 3 dsRNA-gated channel SID-1 RDD PF06271.12 CDS25468.1 - 0.00012 22.3 3.6 0.0015 18.7 1.8 2.5 2 1 0 2 2 2 1 RDD family Filament PF00038.21 CDS25469.1 - 8.8e-53 179.9 53.3 1.3e-52 179.4 53.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.19 CDS25469.1 - 3.9e-12 46.5 0.1 3e-11 43.6 0.2 2.2 2 0 0 2 2 2 1 Lamin Tail Domain APG6_N PF17675.1 CDS25469.1 - 0.011 16.2 11.6 0.011 16.2 11.6 4.4 1 1 2 3 3 2 0 Apg6 coiled-coil region Apolipoprotein PF01442.18 CDS25469.1 - 0.04 13.8 50.0 0.12 12.3 32.6 3.2 1 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 CDS25469.1 - 0.049 12.5 45.1 0.44 9.4 19.4 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 CDS25469.1 - 0.13 11.6 51.3 0.019 14.3 13.1 4.4 1 1 4 5 5 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 CDS25469.1 - 0.25 9.5 41.8 0.052 11.7 14.6 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 CDS25469.1 - 0.59 10.2 57.9 0.056 13.5 8.8 5.8 1 1 5 6 6 5 0 Designed helical repeat protein 10 domain Tektin PF03148.14 CDS25469.1 - 0.64 8.7 43.6 0.031 13.0 19.8 3.5 2 1 1 3 3 3 0 Tektin family FUSC PF04632.12 CDS25469.1 - 0.73 8.3 17.9 1.7 7.0 1.5 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family ATG16 PF08614.11 CDS25469.1 - 0.82 9.9 56.2 0.6 10.3 14.3 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CDS25469.1 - 1.1 9.2 50.3 0.087 12.9 21.7 3.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC_C PF05010.14 CDS25469.1 - 1.4 8.7 40.9 0.06 13.1 8.4 4.3 1 1 3 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 CDS25469.1 - 2.1 8.4 10.8 1.1 9.3 0.3 3.9 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-ATPase_G PF03179.15 CDS25469.1 - 2.3 8.8 27.6 0.031 14.8 7.2 3.9 3 1 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Exonuc_VII_L PF02601.15 CDS25469.1 - 7.5 6.0 34.4 1.8e+04 -10.4 34.4 2.8 1 1 0 1 1 0 0 Exonuclease VII, large subunit Pox_A_type_inc PF04508.12 CDS25469.1 - 9.2 6.3 11.1 0.41 10.6 0.1 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Filament PF00038.21 CDS25470.1 - 1.2e-48 166.4 60.0 7.8e-48 163.6 60.0 1.9 1 1 0 1 1 1 1 Intermediate filament protein Tup_N PF08581.10 CDS25470.1 - 0.00022 21.5 41.7 0.00046 20.4 6.0 6.1 2 2 4 6 6 6 3 Tup N-terminal DUF3584 PF12128.8 CDS25470.1 - 0.0028 15.3 43.5 0.0021 15.7 42.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 CDS25470.1 - 0.0029 16.5 46.9 0.05 12.5 13.4 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 CDS25470.1 - 0.02 15.1 12.6 0.02 15.1 12.6 3.9 1 1 2 3 3 2 0 Tropomyosin like GAS PF13851.6 CDS25470.1 - 0.028 13.8 50.3 0.021 14.2 20.2 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CDS25470.1 - 0.039 13.4 45.2 0.02 14.4 16.5 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF812 PF05667.11 CDS25470.1 - 0.066 12.1 40.6 0.13 11.2 20.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF2576 PF10845.8 CDS25470.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2576) ADIP PF11559.8 CDS25470.1 - 0.44 10.6 46.2 0.46 10.6 8.8 5.4 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.6 CDS25470.1 - 0.85 9.3 46.0 0.034 13.9 15.3 4.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 CDS25470.1 - 1.1 9.4 58.8 5.2 7.2 14.2 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) APC_N_CC PF16689.5 CDS25470.1 - 1.2 9.2 12.8 2.3 8.4 1.1 3.9 4 0 0 4 4 3 0 Coiled-coil N-terminus of APC, dimerisation domain HIP1_clath_bdg PF16515.5 CDS25470.1 - 1.3 9.7 37.9 1.1 9.9 1.4 5.0 2 2 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 CDS25470.1 - 1.3 8.3 41.9 2.4 7.4 18.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tektin PF03148.14 CDS25470.1 - 1.3 7.7 47.7 0.32 9.7 19.8 2.8 1 1 1 2 2 2 0 Tektin family TPR_MLP1_2 PF07926.12 CDS25470.1 - 1.8 8.6 49.4 0.16 12.1 3.0 4.1 1 1 3 4 4 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 CDS25470.1 - 2.4 7.4 36.1 0.59 9.4 8.8 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CDS25470.1 - 2.5 8.6 63.0 0.62 10.6 19.4 5.2 1 1 4 5 5 4 0 Apg6 coiled-coil region Leu_zip PF15294.6 CDS25470.1 - 5.7 6.4 42.7 1.9 8.0 14.6 3.1 1 1 2 3 3 3 0 Leucine zipper AAA_13 PF13166.6 CDS25470.1 - 9.1 4.8 35.7 0.099 11.3 9.4 2.9 1 1 1 2 2 2 0 AAA domain TFIIS_C PF01096.18 CDS25472.1 - 4e-12 45.8 1.3 4e-12 45.8 1.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 CDS25472.1 - 0.0058 16.6 3.8 1.5 8.9 0.1 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DZR PF12773.7 CDS25472.1 - 0.0091 16.0 2.6 0.7 10.0 0.9 2.6 2 1 0 2 2 2 1 Double zinc ribbon NOB1_Zn_bind PF08772.11 CDS25472.1 - 0.024 14.8 3.9 0.15 12.2 0.0 2.6 2 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like GFA PF04828.14 CDS25472.1 - 0.059 13.7 1.5 0.51 10.7 0.0 2.6 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.8 CDS25472.1 - 0.081 13.3 0.2 0.081 13.3 0.2 2.1 2 1 0 2 2 2 0 zinc-finger-containing domain RNA_POL_M_15KD PF02150.16 CDS25472.1 - 0.39 10.6 4.1 1.9 8.4 1.0 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 CDS25472.1 - 0.57 10.5 5.6 2.4 8.5 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_2 PF13240.6 CDS25472.1 - 1.3 8.9 8.9 5.7 6.8 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DAP PF15228.6 CDS25474.1 - 5.4e-07 30.7 8.5 1.2e-06 29.5 8.5 1.5 1 1 0 1 1 1 1 Death-associated protein Guanylate_cyc PF00211.20 CDS25475.1 - 7.9e-67 224.4 0.0 8.5e-66 221.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.28 CDS25475.1 - 7.4e-59 199.6 0.1 6.4e-48 163.7 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Pkinase_Tyr PF07714.17 CDS25475.1 - 4e-35 121.4 0.0 7.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25475.1 - 5e-32 111.3 0.0 1.8e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HNOBA PF07701.14 CDS25475.1 - 0.0013 18.3 0.3 0.0013 18.3 0.3 2.2 2 0 0 2 2 2 1 Heme NO binding associated Ribosomal_L36e PF01158.18 CDS25475.1 - 0.022 15.0 1.3 0.049 13.9 1.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e SKG6 PF08693.10 CDS25475.1 - 0.048 13.1 0.6 0.13 11.7 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IPU_b_solenoid PF18783.1 CDS25475.1 - 0.14 12.3 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat NOA36 PF06524.12 CDS25476.1 - 4.6e-128 426.9 39.3 5.6e-128 426.6 39.3 1.0 1 0 0 1 1 1 1 NOA36 protein FYDLN_acid PF09538.10 CDS25476.1 - 0.0029 18.2 3.9 0.0029 18.2 3.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 CDS25476.1 - 0.91 7.6 5.6 1.4 7.1 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 CDS25476.1 - 1.7 8.4 7.7 10 5.9 0.9 2.8 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Cofilin_ADF PF00241.20 CDS25477.1 - 8e-33 112.8 0.0 1.1e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein His_Phos_2 PF00328.22 CDS25478.1 - 6.5e-20 71.8 0.1 2.2e-19 70.1 0.0 1.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) OppC_N PF12911.7 CDS25478.1 - 0.034 14.1 0.1 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C UL41A PF17591.2 CDS25478.1 - 0.77 9.9 2.7 0.88 9.7 1.5 1.7 2 0 0 2 2 2 0 Herpesvirus UL41A efThoc1 PF11957.8 CDS25479.1 - 8.3e-85 285.3 29.1 2e-84 284.1 22.1 2.8 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor Rrp44_CSD1 PF17216.3 CDS25479.1 - 0.61 9.8 4.0 1.3 8.8 4.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain GDP_Man_Dehyd PF16363.5 CDS25480.1 - 3.7e-55 187.6 0.0 4.5e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDS25480.1 - 1.1e-49 169.1 0.0 1.4e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDS25480.1 - 6.8e-15 55.0 0.0 7.7e-14 51.5 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDS25480.1 - 1.4e-14 53.7 0.0 8.5e-14 51.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDS25480.1 - 1.2e-11 44.3 0.0 1.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CDS25480.1 - 7.2e-08 31.9 0.0 8.7e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 CDS25480.1 - 1.7e-06 28.1 0.0 3.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDS25480.1 - 2.3e-06 27.7 0.0 6.4e-06 26.2 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CDS25480.1 - 0.0055 16.2 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CDS25480.1 - 0.058 12.9 0.1 3 7.4 0.0 2.4 2 1 0 2 2 2 0 NmrA-like family SID PF11778.8 CDS25480.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Septation initiation Sacchrp_dh_NADP PF03435.18 CDS25480.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain KH_1 PF00013.29 CDS25482.1 - 4.1e-07 29.7 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 KH domain TUDOR PF00567.24 CDS25482.1 - 2e-06 27.8 0.2 4.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Tudor domain KH_2 PF07650.17 CDS25482.1 - 0.00042 20.1 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CDS25482.1 - 0.029 14.2 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 KH domain TUDOR PF00567.24 CDS25483.1 - 1.8e-09 37.7 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.29 CDS25483.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 KH domain Cupin_2 PF07883.11 CDS25484.1 - 4.4e-11 42.3 0.1 6.5e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 CDS25484.1 - 0.00021 21.1 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Fucose_iso_C PF02952.17 CDS25484.1 - 0.0014 18.4 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 L-fucose isomerase, C-terminal domain Cupin_1 PF00190.22 CDS25484.1 - 0.0023 17.6 0.0 0.0044 16.6 0.0 1.4 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 CDS25484.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.12 CDS25484.1 - 0.044 13.3 0.0 0.059 12.8 0.0 1.3 1 1 0 1 1 1 0 Cupin superfamily protein Lyx_isomer PF07385.12 CDS25484.1 - 0.069 12.4 0.1 0.087 12.1 0.1 1.3 1 1 0 1 1 1 0 D-lyxose isomerase DUF4437 PF14499.6 CDS25484.1 - 0.11 11.6 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Neur_chan_LBD PF02931.23 CDS25485.1 - 7.8e-116 385.0 7.7 9.1e-58 195.2 1.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS25485.1 - 1.1e-88 297.4 8.2 1e-40 140.3 1.3 3.1 2 1 1 3 3 3 3 Neurotransmitter-gated ion-channel transmembrane region Cupin_2 PF07883.11 CDS25485.1 - 2e-10 40.2 0.2 3.9e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDS25485.1 - 0.00085 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.12 CDS25485.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 CDS25485.1 - 0.058 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 CDS25485.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Usp PF00582.26 CDS25486.1 - 2e-18 67.3 0.0 3.7e-16 59.9 0.0 2.6 1 1 0 1 1 1 1 Universal stress protein family RhoGAP PF00620.27 CDS25487.1 - 6.5e-14 52.0 0.0 2.3e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain PRIMA1 PF16101.5 CDS25488.1 - 0.1 12.7 4.9 0.12 12.4 4.9 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 CDS25488.1 - 0.38 10.8 3.2 0.39 10.8 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CDS25488.1 - 4.1 6.8 5.1 4.9 6.5 5.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VHP PF02209.19 CDS25490.2 - 1.4e-16 60.3 1.0 2.7e-16 59.3 1.0 1.5 1 0 0 1 1 1 1 Villin headpiece domain LIM PF00412.22 CDS25490.2 - 1.9e-09 37.6 18.6 6.4e-06 26.3 6.8 2.4 2 0 0 2 2 2 2 LIM domain RT_RNaseH PF17917.1 CDS25491.2 - 5.2e-26 91.0 0.7 1.1e-25 89.9 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS25491.2 - 2.4e-22 78.8 0.2 5.8e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDS25491.2 - 1.1e-11 44.7 0.7 1.9e-11 43.9 0.7 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDS25491.2 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CDS25491.2 - 0.019 15.2 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Exo_endo_phos_2 PF14529.6 CDS25492.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AHL_synthase PF17327.2 CDS25492.1 - 0.0061 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Acyl homoserine lactone synthase RNase_H PF00075.24 CDS25493.1 - 3.8e-08 33.6 0.0 5.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNase H Col_cuticle_N PF01484.17 CDS25495.1 - 0.63 10.2 2.0 0.94 9.6 2.0 1.4 1 1 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF4471 PF14740.6 CDS25498.1 - 2e-77 260.5 0.0 6.7e-77 258.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) VHS PF00790.19 CDS25500.1 - 8.3e-31 106.7 0.0 2.7e-30 105.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CDS25500.1 - 1.3e-21 76.7 3.9 1.3e-21 76.7 3.9 2.6 2 0 0 2 2 2 1 GAT domain ENTH PF01417.20 CDS25500.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 ENTH domain KorB PF08535.10 CDS25500.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 KorB domain PBECR1 PF18809.1 CDS25501.1 - 0.075 13.7 0.8 0.098 13.3 0.8 1.3 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 DUF3995 PF13160.6 CDS25502.1 - 0.34 11.3 8.4 0.06 13.7 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Pelovaterin PF17859.1 CDS25502.1 - 4.1 7.8 0.0 4.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Pelovaterin Claudin_2 PF13903.6 CDS25502.1 - 4.9 6.8 14.0 4.2 7.1 11.7 2.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Sua5_yciO_yrdC PF01300.18 CDS25503.1 - 3.8e-36 124.3 0.0 5.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination Brix PF04427.18 CDS25504.1 - 4.5e-32 111.7 0.1 6.4e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Calcipressin PF04847.12 CDS25505.1 - 6.5e-28 97.7 7.0 2.9e-19 69.5 3.5 2.2 2 0 0 2 2 2 2 Calcipressin LRR_8 PF13855.6 CDS25506.1 - 9.1e-07 28.5 15.6 7.3e-05 22.5 1.1 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CDS25506.1 - 1.2e-06 28.8 12.8 1.8e-05 25.0 2.5 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS25506.1 - 1e-05 25.1 2.5 0.00028 20.4 0.8 3.2 2 1 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDS25506.1 - 0.12 12.5 0.6 9.1 6.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 CDS25506.1 - 0.31 11.7 6.3 3.3 8.6 1.5 3.4 3 1 0 3 3 3 0 Leucine Rich Repeat RRM_1 PF00076.22 CDS25507.1 - 2.5e-05 24.0 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 CDS25508.2 - 4.4e-34 117.8 0.1 9.7e-34 116.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS25508.2 - 1.4e-23 83.4 0.6 3.8e-22 78.7 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 CDS25508.2 - 0.0029 17.8 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain T2SSE PF00437.20 CDS25508.2 - 0.054 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein EGF_CA PF07645.15 CDS25509.2 - 4.5e-05 23.6 8.4 0.036 14.3 0.5 3.2 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 CDS25509.2 - 0.00037 20.4 4.4 0.33 10.9 0.3 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDS25509.2 - 0.0027 17.9 10.5 0.11 12.8 1.6 2.6 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDS25509.2 - 0.0051 17.0 6.4 0.52 10.5 1.4 2.5 2 0 0 2 2 2 2 EGF domain EGF PF00008.27 CDS25509.2 - 0.027 14.8 11.2 0.37 11.1 2.9 2.8 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 CDS25509.2 - 0.038 14.6 13.3 0.19 12.4 2.4 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CDS25509.2 - 0.1 12.6 1.1 4.1 7.5 0.1 2.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CDS25509.2 - 0.2 12.0 1.1 15 6.0 0.2 2.7 2 0 0 2 2 2 0 Pvs28 EGF domain NYD-SP28 PF14772.6 CDS25510.1 - 1.3e-24 86.1 9.4 1.3e-24 86.1 9.4 5.7 3 1 1 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 CDS25510.1 - 2.4e-11 43.6 3.0 2.4e-11 43.6 3.0 5.2 4 1 1 5 5 5 1 Sperm tail C-terminal domain Cnn_1N PF07989.11 CDS25510.1 - 0.01 15.9 1.5 0.01 15.9 1.5 5.7 4 2 1 5 5 5 0 Centrosomin N-terminal motif 1 HTH_48 PF17906.1 CDS25511.1 - 0.047 13.8 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Trypsin PF00089.26 CDS25513.1 - 4.5e-50 170.5 0.1 9.9e-31 107.3 0.0 2.2 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CDS25513.1 - 0.00059 20.8 0.0 0.0021 18.9 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Raf1_HTH PF18579.1 CDS25514.1 - 0.0001 21.9 1.5 0.00014 21.5 0.1 1.9 2 0 0 2 2 2 1 Rubisco accumulation factor 1 helix turn helix domain NAT PF04768.13 CDS25514.1 - 0.0089 15.7 3.7 0.022 14.4 1.2 2.3 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Seryl_tRNA_N PF02403.22 CDS25514.1 - 0.014 15.6 26.7 0.33 11.2 6.3 3.9 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.6 CDS25514.1 - 0.23 11.2 30.8 0.89 9.3 13.2 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DivIVA PF05103.13 CDS25514.1 - 0.35 11.0 23.1 0.023 14.8 15.1 2.9 1 1 1 3 3 3 0 DivIVA protein HAUS-augmin3 PF14932.6 CDS25514.1 - 0.39 10.2 30.0 0.17 11.4 11.8 3.2 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Sulfatase_C PF14707.6 CDS25514.1 - 2 9.2 5.3 1 10.1 1.4 2.3 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase YabA PF06156.13 CDS25514.1 - 2.5 8.8 23.7 3.4 8.3 7.1 3.1 2 2 1 3 3 3 0 Initiation control protein YabA DUF4200 PF13863.6 CDS25514.1 - 3.5 8.0 36.1 1.1 9.7 10.5 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) T3SSipB PF16535.5 CDS25514.1 - 4.6 7.7 10.4 16 5.9 2.1 2.6 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF745 PF05335.13 CDS25514.1 - 4.7 6.9 18.3 0.89 9.2 14.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PAS_10 PF13596.6 CDS25514.1 - 5.7 7.6 6.1 2.9 8.5 0.4 3.0 2 2 1 3 3 3 0 PAS domain Fz PF01392.22 CDS25515.1 - 3.2e-28 98.6 2.7 6.1e-28 97.7 2.7 1.4 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 CDS25515.1 - 6.1e-28 97.8 3.0 1.5e-24 86.7 1.1 2.1 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region RVT_1 PF00078.27 CDS25518.1 - 6.7e-23 81.4 0.0 9.7e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDS25518.1 - 1.4e-11 44.6 0.0 3.5e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS25518.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF2796 PF10986.8 CDS25518.1 - 0.1 12.6 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) WD40 PF00400.32 CDS25521.2 - 2.5e-28 97.7 8.1 3e-05 24.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25521.2 - 3.2e-14 53.0 0.0 0.0036 17.6 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS25521.2 - 0.00028 20.0 4.1 1.6 7.6 0.2 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS25521.2 - 0.00028 20.8 0.0 0.0021 18.0 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 CDS25521.2 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 CDS25521.2 - 0.053 12.0 0.0 0.086 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 CDS25521.2 - 0.21 10.9 0.0 5.5 6.2 0.0 2.8 3 1 1 4 4 4 0 WD40-like domain GLE1 PF07817.13 CDS25522.1 - 0.057 12.6 0.7 0.18 11.0 0.7 1.8 1 1 0 1 1 1 0 GLE1-like protein DUF4570 PF15134.6 CDS25522.1 - 0.33 11.0 1.3 6.2 6.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Pribosyltran PF00156.27 CDS25523.1 - 2.2e-11 43.6 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain OMPdecase PF00215.24 CDS25523.1 - 5.7e-09 35.9 0.0 2e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TRAP-delta PF05404.12 CDS25524.1 - 4e-28 98.0 0.0 4.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) Ldl_recept_a PF00057.18 CDS25525.1 - 1.9e-07 31.2 6.1 1.9e-07 31.2 6.1 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A EB PF01683.18 CDS25525.1 - 0.0016 18.7 4.8 0.0016 18.7 4.8 2.3 2 0 0 2 2 2 1 EB module SNF PF00209.18 CDS25528.1 - 2.1e-205 683.4 34.3 2.4e-205 683.2 34.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF1304 PF06993.12 CDS25528.1 - 0.077 13.0 1.1 0.24 11.4 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) PGF-CTERM PF18204.1 CDS25528.1 - 0.17 11.9 1.8 1.4 9.0 0.8 2.5 2 0 0 2 2 2 0 PGF-CTERM motif His_Phos_2 PF00328.22 CDS25529.1 - 1e-07 31.7 0.0 9.2e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 CDS25530.1 - 2.9e-11 43.4 0.0 6e-09 35.7 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PH_TFIIH PF08567.11 CDS25530.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain MIF4G PF02854.19 CDS25531.1 - 1.2e-28 100.3 1.3 1.2e-28 100.3 1.3 2.0 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.18 CDS25531.1 - 3.3e-11 43.2 0.1 7.4e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RVT_1 PF00078.27 CDS25532.1 - 9.8e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1054 PF06335.12 CDS25532.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) NYD-SP28 PF14772.6 CDS25533.1 - 0.013 15.6 1.8 0.013 15.6 1.8 3.5 2 1 0 3 3 3 0 Sperm tail NEMO PF11577.8 CDS25533.1 - 0.015 15.3 2.0 0.015 15.3 2.0 3.1 4 0 0 4 4 4 0 NF-kappa-B essential modulator NEMO DUF3885 PF13021.6 CDS25533.1 - 0.19 11.9 0.5 0.48 10.6 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) IQ PF00612.27 CDS25533.1 - 0.7 9.8 6.2 1.6 8.8 1.5 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif DUF948 PF06103.11 CDS25533.1 - 2.8 8.2 4.9 28 5.1 3.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.6 CDS25533.1 - 4 7.9 21.5 8.9 6.7 7.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) rve PF00665.26 CDS25534.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS25534.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Ion_trans PF00520.31 CDS25535.1 - 0.0018 17.5 4.3 0.0033 16.7 4.3 1.3 1 0 0 1 1 1 1 Ion transport protein zf-C2H2 PF00096.26 CDS25537.1 - 1.4e-05 25.3 24.3 0.021 15.2 1.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS25537.1 - 2.3e-05 24.8 21.9 0.029 15.2 1.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS25537.1 - 0.00053 19.9 0.4 0.00053 19.9 0.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 CDS25537.1 - 0.00079 19.7 8.5 0.0034 17.7 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CDS25537.1 - 0.0011 19.2 3.1 0.0011 19.2 3.1 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CDS25537.1 - 0.0043 17.3 0.1 0.0043 17.3 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS25537.1 - 0.56 10.5 5.1 0.38 11.1 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDS25537.1 - 1.6 8.6 11.2 14 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CDS25537.1 - 1.8 9.1 19.2 0.72 10.4 0.4 4.6 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CDS25537.1 - 3.6 8.3 10.4 1.9 9.2 2.6 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Cadherin PF00028.17 CDS25538.1 - 4.8e-56 187.2 1.2 1.2e-11 44.9 0.4 6.9 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CDS25538.1 - 3.2e-07 30.1 0.0 0.02 14.7 0.0 4.9 4 1 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CDS25538.1 - 0.0027 17.7 7.6 1.8 8.6 0.0 5.8 8 0 0 8 8 8 1 Cadherin-like EB1_binding PF05937.11 CDS25538.1 - 0.0045 17.6 0.0 0.013 16.1 0.0 1.8 1 0 0 1 1 1 1 EB-1 Binding Domain FctA PF12892.7 CDS25538.1 - 0.03 15.1 3.3 6.9 7.5 0.1 3.6 3 1 1 4 4 4 0 Spy0128-like isopeptide containing domain Y_Y_Y PF07495.13 CDS25538.1 - 0.048 13.6 0.9 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Y_Y_Y domain Ferritin PF00210.24 CDS25540.1 - 3.5e-14 52.9 2.5 4.5e-14 52.6 2.5 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 CDS25540.1 - 0.007 16.8 1.2 0.015 15.7 1.2 1.7 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 CDS25541.1 - 1.8e-23 83.0 3.6 2.3e-23 82.7 3.6 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 CDS25541.1 - 0.00099 19.5 2.7 0.0031 17.9 2.7 1.9 1 1 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 CDS25541.1 - 0.054 13.9 3.7 3.2 8.1 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) COQ7 PF03232.13 CDS25541.1 - 0.071 12.9 0.4 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 NCE101 PF11654.8 CDS25541.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 Lzipper-MIP1 PF14389.6 CDS25541.1 - 0.099 13.0 1.3 0.15 12.4 0.2 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Coat_F PF07875.12 CDS25541.1 - 2.3 8.5 4.9 2 8.7 0.1 2.8 3 1 0 3 3 3 0 Coat F domain NCBP3 PF10309.9 CDS25543.1 - 0.00016 21.4 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 HemY_N PF07219.13 CDS25544.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.0 3 0 0 3 3 3 0 HemY protein N-terminus P34-Arc PF04045.14 CDS25545.1 - 1.8e-85 286.5 0.4 2.3e-85 286.2 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Thioredoxin_6 PF13848.6 CDS25546.1 - 1.9e-23 83.3 0.5 9.7e-23 81.0 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CDS25546.1 - 1.4e-18 66.7 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin CH PF00307.31 CDS25547.2 - 4.8e-09 36.4 0.2 1.5e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 CDS25547.2 - 0.0012 18.9 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein Herpes_BLRF2 PF05812.12 CDS25547.2 - 0.014 15.5 1.9 0.042 14.0 0.8 2.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 CDS25547.2 - 0.015 15.6 1.4 0.015 15.6 1.4 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 CDS25547.2 - 0.028 15.0 0.2 0.028 15.0 0.2 2.7 3 0 0 3 3 3 0 Initiation control protein YabA FlgN PF05130.12 CDS25547.2 - 0.053 14.0 3.6 0.16 12.4 3.6 1.8 1 0 0 1 1 1 0 FlgN protein ATP-synt_F6 PF05511.11 CDS25548.1 - 4.4e-16 59.1 0.2 5.8e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 DUF4023 PF13215.6 CDS25548.1 - 0.17 11.9 0.6 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Choline_kinase PF01633.20 CDS25549.1 - 4.2e-43 147.4 0.5 1.2e-42 145.9 0.5 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CDS25549.1 - 9.5e-11 42.1 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDS25549.1 - 0.23 10.7 2.7 0.39 10.0 2.7 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase Thioredoxin PF00085.20 CDS25550.1 - 2.9e-22 78.6 0.5 3.8e-22 78.2 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDS25550.1 - 2.9e-06 27.7 0.3 3.9e-05 24.1 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDS25550.1 - 0.00012 22.1 0.2 0.00019 21.6 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CDS25550.1 - 0.00021 21.5 0.1 0.015 15.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CDS25550.1 - 0.0044 16.4 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CDS25550.1 - 0.0052 16.8 0.1 0.0096 16.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin domain DIM1 PF02966.16 CDS25550.1 - 0.0058 16.4 0.3 0.0076 16.0 0.3 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF4180 PF13788.6 CDS25550.1 - 0.044 13.7 0.1 0.14 12.1 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4180) HyaE PF07449.11 CDS25550.1 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE CHD5 PF04420.14 CDS25550.1 - 0.063 13.1 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 CHD5-like protein KaiB PF07689.12 CDS25550.1 - 0.09 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 KaiB domain Ank_2 PF12796.7 CDS25551.1 - 1e-59 199.0 3.6 2.7e-14 53.5 0.0 6.4 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25551.1 - 1.2e-44 150.1 12.5 9.2e-08 32.5 0.0 10.3 5 3 7 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS25551.1 - 9.7e-43 139.3 15.1 0.0096 16.4 0.0 12.7 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 CDS25551.1 - 4e-40 134.5 25.4 0.0013 19.1 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 CDS25551.1 - 1.8e-37 126.9 17.4 5.3e-07 29.8 1.2 10.7 5 2 6 11 11 11 9 Ankyrin repeats (many copies) SOCS_box PF07525.16 CDS25551.1 - 7e-08 32.7 1.0 2e-07 31.2 1.0 1.8 1 0 0 1 1 1 1 SOCS box Ig_3 PF13927.6 CDS25554.1 - 7.6e-27 93.7 1.4 1.9e-07 31.6 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain ig PF00047.25 CDS25554.1 - 4.2e-16 58.9 0.3 0.00016 21.8 0.0 4.7 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS25554.1 - 6.1e-16 58.3 0.0 7.6e-05 22.7 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS25554.1 - 1.3e-14 54.3 0.3 0.001 19.3 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CDS25554.1 - 1.1e-08 35.2 0.2 0.021 15.0 0.0 4.7 4 1 1 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDS25554.1 - 0.011 15.8 0.0 4.8 7.3 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain EphA2_TM PF14575.6 CDS25554.1 - 0.068 14.1 0.0 0.068 14.1 0.0 3.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain HemY_N PF07219.13 CDS25554.1 - 1.9 8.7 5.5 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF4381 PF14316.6 CDS25554.1 - 4 7.7 5.1 0.64 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) BAH PF01426.18 CDS25556.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 BAH domain PHD PF00628.29 CDS25556.1 - 0.18 11.7 3.8 0.15 12.0 0.9 2.2 2 0 0 2 2 2 0 PHD-finger HECT PF00632.25 CDS25557.1 - 1.1e-99 333.8 0.0 1.7e-99 333.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CDS25557.1 - 6.3e-44 147.7 16.4 4.1e-12 46.0 0.3 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.30 CDS25557.1 - 2.2e-20 72.9 0.0 6.4e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain MbtH PF03621.13 CDS25557.1 - 0.16 11.4 2.2 26 4.3 0.0 4.1 5 0 0 5 5 5 0 MbtH-like protein WW_1 PF18507.1 CDS25557.1 - 0.3 10.8 3.5 9.9 6.0 0.2 3.0 3 0 0 3 3 3 0 WW domain ThuA PF06283.11 CDS25557.1 - 3.9 7.6 4.8 87 3.2 0.0 4.2 3 2 1 4 4 4 0 Trehalose utilisation RRM_1 PF00076.22 CDS25558.1 - 1e-36 124.6 0.0 1.7e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM176 PF14851.6 CDS25558.1 - 5.6e-05 22.8 0.4 9.2e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 FAM176 family RRM_occluded PF16842.5 CDS25558.1 - 0.049 13.5 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 CDS25559.1 - 9.5e-17 60.6 0.0 1.4e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS25559.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 CDS25559.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif PRCC PF10253.9 CDS25560.1 - 1e-18 69.0 9.7 3.1e-18 67.4 9.7 1.8 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting AAA PF00004.29 CDS25563.1 - 1.4e-35 122.6 0.0 2.3e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS25563.1 - 4.4e-11 42.4 0.0 1.4e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 CDS25563.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS25563.1 - 0.00019 21.8 0.1 0.00042 20.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDS25563.1 - 0.00028 21.2 0.2 0.0033 17.7 0.2 2.7 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDS25563.1 - 0.00041 19.7 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CDS25563.1 - 0.0017 18.3 0.0 0.0055 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDS25563.1 - 0.0047 17.1 0.0 0.0099 16.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDS25563.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDS25563.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CDS25563.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS25563.1 - 0.017 15.5 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 CDS25563.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS25563.1 - 0.034 13.7 0.0 0.087 12.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 CDS25563.1 - 0.036 14.0 0.1 0.17 11.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 CDS25563.1 - 0.061 12.7 0.0 0.99 8.7 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 CDS25563.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDS25563.1 - 0.095 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CDS25563.1 - 0.097 12.4 0.0 0.74 9.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 CDS25563.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CDS25563.1 - 0.12 12.0 0.2 0.52 9.9 0.3 2.0 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CDS25563.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CDS25563.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 CDS25563.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 CDS25563.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDS25563.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDS25563.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CDS25563.1 - 0.21 11.3 0.1 0.42 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.23 CDS25564.1 - 3e-14 52.7 0.1 4.3e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDS25564.1 - 1.1e-09 38.6 0.1 1.7e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region YwqJ-deaminase PF14431.6 CDS25564.1 - 0.057 13.6 0.7 1.5 9.0 0.0 2.5 1 1 2 3 3 3 0 YwqJ-like deaminase Mal_decarbox_Al PF16957.5 CDS25564.1 - 0.14 10.5 0.1 0.23 9.7 0.1 1.4 1 1 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter PPTA PF01239.22 CDS25565.2 - 1.1e-12 47.3 3.2 2.8e-06 26.9 0.4 4.9 4 1 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat betaPIX_CC PF16523.5 CDS25565.2 - 0.23 11.3 0.9 0.41 10.5 0.9 1.3 1 0 0 1 1 1 0 betaPIX coiled coil MFS_1 PF07690.16 CDS25566.1 - 4.2e-42 144.3 29.0 2.5e-38 131.9 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDS25566.1 - 1.1e-07 30.5 0.1 1.1e-07 30.5 0.1 2.4 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CDS25566.1 - 0.0023 16.9 7.2 0.0023 16.9 7.2 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Tetraspanin PF00335.20 CDS25567.1 - 5.4e-06 26.3 32.1 5.4e-06 26.3 32.1 2.0 1 1 1 2 2 2 1 Tetraspanin family Aminoglyc_resit PF10706.9 CDS25567.1 - 0.028 14.2 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Tetraspanin PF00335.20 CDS25568.1 - 8.8e-27 94.3 9.8 1.3e-26 93.8 9.8 1.2 1 1 0 1 1 1 1 Tetraspanin family Chlam_OMP3 PF03503.13 CDS25568.1 - 0.038 14.3 2.2 0.075 13.4 2.2 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 TMEM154 PF15102.6 CDS25568.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.6 3 1 0 3 3 3 0 TMEM154 protein family Tetraspanin PF00335.20 CDS25569.1 - 1.1e-20 74.3 17.1 1.7e-20 73.7 17.1 1.3 1 1 0 1 1 1 1 Tetraspanin family Inhibitor_I53 PF11714.8 CDS25569.1 - 0.2 11.9 0.1 0.47 10.7 0.1 1.7 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Tetraspanin PF00335.20 CDS25570.1 - 1.9e-23 83.4 20.2 2.4e-23 83.0 20.2 1.2 1 0 0 1 1 1 1 Tetraspanin family PRRSV_2b PF07069.11 CDS25570.1 - 0.046 14.2 4.3 0.046 14.2 4.3 3.0 2 1 2 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b Ion_trans PF00520.31 CDS25571.2 - 4.2e-19 68.7 17.9 2.2e-18 66.4 17.9 2.0 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CDS25571.2 - 0.0046 15.7 21.8 0.01 14.6 0.9 3.1 2 1 0 2 2 2 2 Polycystin cation channel Syndecan PF01034.20 CDS25571.2 - 0.65 9.9 0.0 0.65 9.9 0.0 2.8 3 0 0 3 3 3 0 Syndecan domain Ldl_recept_a PF00057.18 CDS25577.1 - 3.4e-05 24.0 7.0 5.2e-05 23.4 7.0 1.3 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A NDK PF00334.19 CDS25578.1 - 8.5e-28 97.0 0.0 1.1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TFIIF_beta PF02270.15 CDS25579.1 - 9.3e-25 86.5 0.3 1.6e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CDS25579.1 - 2.8e-24 86.3 0.1 5.7e-24 85.3 0.0 1.5 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus Sec5 PF15469.6 CDS25580.1 - 1.5e-36 126.0 0.0 2.9e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 TIG PF01833.24 CDS25580.1 - 2e-06 27.8 0.3 5.7e-06 26.3 0.3 1.8 1 0 0 1 1 1 1 IPT/TIG domain Phage_prot_Gp6 PF05133.14 CDS25581.1 - 0.081 12.0 0.1 0.092 11.8 0.1 1.0 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Sterol-sensing PF12349.8 CDS25583.2 - 6.3e-24 84.6 6.4 6.3e-24 84.6 6.4 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDS25583.2 - 4.7e-18 64.7 14.2 7e-16 57.5 3.1 3.0 3 0 0 3 3 3 2 Patched family Anp1 PF03452.14 CDS25584.1 - 0.00014 21.4 0.8 0.39 10.1 0.1 3.2 3 1 1 4 4 4 2 Anp1 Anp1 PF03452.14 CDS25585.1 - 0.0011 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Anp1 Anp1 PF03452.14 CDS25586.1 - 0.0047 16.4 0.1 0.026 13.9 0.0 2.2 3 0 0 3 3 3 1 Anp1 2OG-FeII_Oxy_3 PF13640.6 CDS25586.1 - 0.018 15.9 0.1 0.044 14.7 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CDS25587.1 - 0.00033 21.5 0.2 0.01 16.7 0.2 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glycos_transf_2 PF00535.26 CDS25587.1 - 0.016 15.0 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 WD40 PF00400.32 CDS25588.1 - 3.5e-14 53.0 8.8 0.00017 22.3 0.0 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25588.1 - 1.6e-05 25.1 0.6 0.002 18.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS25588.1 - 0.0025 16.8 0.4 0.87 8.5 0.3 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2428 PF10350.9 CDS25591.1 - 6.9e-17 61.6 0.3 1.5e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CDS25591.1 - 0.00033 20.7 0.0 0.29 11.5 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CDS25591.1 - 0.0097 16.3 0.0 3.2 8.2 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats Ndc80_HEC PF03801.13 CDS25594.1 - 9.5e-20 70.8 0.0 2.9e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family ESAG1 PF03238.13 CDS25594.1 - 0.0059 16.1 2.3 0.17 11.3 0.0 2.5 2 1 0 2 2 2 1 ESAG protein SKA2 PF16740.5 CDS25594.1 - 0.014 15.1 2.3 0.014 15.1 2.3 4.6 2 2 2 5 5 5 0 Spindle and kinetochore-associated protein 2 Cortex-I_coil PF09304.10 CDS25594.1 - 0.016 15.4 1.2 0.016 15.4 1.2 3.9 2 2 0 3 3 3 0 Cortexillin I, coiled coil Spc7 PF08317.11 CDS25594.1 - 0.09 11.6 46.1 0.33 9.8 5.9 3.8 2 2 1 3 3 3 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 CDS25594.1 - 0.11 12.8 21.5 0.079 13.3 0.9 4.7 3 2 0 3 3 3 0 Syntaxin-like protein Ribosomal_S13 PF00416.22 CDS25594.1 - 1.4 9.3 6.8 0.38 11.2 1.6 2.5 2 1 0 2 2 2 0 Ribosomal protein S13/S18 ADIP PF11559.8 CDS25594.1 - 1.5 8.9 34.0 0.66 10.1 1.3 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 CDS25594.1 - 2 7.9 41.3 0.045 13.3 5.5 3.5 1 1 0 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 CDS25594.1 - 2.6 8.1 19.6 2 8.5 0.9 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDS25594.1 - 4.5 7.5 24.8 7.6 6.7 0.2 4.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CDS25594.1 - 5.3 7.4 10.9 28 5.1 0.4 4.1 3 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 CDS25594.1 - 5.8 7.0 45.2 0.23 11.5 6.3 4.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 CDS25594.1 - 9.6 6.3 32.7 0.042 13.9 10.7 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Voldacs PF03517.13 CDS25595.1 - 4.7e-26 91.6 0.2 6.2e-26 91.2 0.2 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Tetraspanin PF00335.20 CDS25597.1 - 6.9e-12 45.6 1.2 1.3e-11 44.7 1.2 1.4 1 0 0 1 1 1 1 Tetraspanin family EF-hand_11 PF08976.11 CDS25597.1 - 2.9e-10 41.0 0.5 0.0016 19.3 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDS25597.1 - 9.7e-10 38.8 6.6 7.8e-07 29.5 0.2 5.2 6 0 0 6 6 6 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS25597.1 - 1.2e-06 28.2 7.9 0.011 15.6 0.1 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS25597.1 - 6.9e-06 25.6 2.0 2.6 8.2 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 CDS25597.1 - 6e-05 22.3 2.4 21 5.0 0.1 6.2 8 0 0 8 8 8 2 EF hand Cyclase PF04199.13 CDS25597.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative cyclase Palm_thioest PF02089.15 CDS25598.1 - 2.5e-84 282.9 0.0 2.9e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CDS25598.1 - 0.00074 19.2 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDS25598.1 - 0.0096 15.7 1.5 0.24 11.1 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 CDS25598.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) RhoGEF PF00621.20 CDS25599.1 - 2.1e-30 106.3 0.5 5.6e-29 101.7 0.0 3.2 3 0 0 3 3 3 1 RhoGEF domain Spectrin PF00435.21 CDS25599.1 - 2.2e-19 69.9 38.8 1.1e-07 32.3 3.4 7.2 8 0 0 8 8 8 4 Spectrin repeat PH PF00169.29 CDS25599.1 - 0.0044 17.5 0.1 0.017 15.6 0.0 2.0 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 CDS25599.1 - 0.008 16.2 0.5 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_10 PF15411.6 CDS25599.1 - 0.11 12.8 0.1 0.39 11.0 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1488 PF07369.11 CDS25599.1 - 0.14 12.1 0.5 2.4 8.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) BLOC1_2 PF10046.9 CDS25599.1 - 2.3 8.6 5.3 63 4.0 0.0 4.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2630 PF10944.8 CDS25599.1 - 5 7.7 6.1 3.3 8.2 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Pescadillo_N PF06732.11 CDS25601.1 - 3.2e-82 276.1 0.2 7.7e-82 274.9 0.2 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 CDS25601.1 - 6.4e-10 39.3 0.0 3.6e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDS25601.1 - 0.074 13.4 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PTPlike_phytase PF14566.6 CDS25601.1 - 0.93 9.6 5.2 0.69 10.0 3.0 2.0 1 1 0 1 1 1 0 Inositol hexakisphosphate TruB_N PF01509.18 CDS25602.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CDS25602.1 - 0.17 12.1 0.0 0.89 9.7 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain CLTH PF10607.9 CDS25603.1 - 3.5e-14 52.9 0.0 6.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 CDS25603.1 - 3.9e-12 46.4 0.1 7e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 SPRY domain TRAP-gamma PF07074.12 CDS25603.1 - 0.097 12.2 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LisH PF08513.11 CDS25603.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 LisH ATP-cone PF03477.16 CDS25603.1 - 0.16 12.5 0.1 0.4 11.3 0.1 1.6 1 0 0 1 1 1 0 ATP cone domain Flocculin_t3 PF13928.6 CDS25604.1 - 6.2 7.4 8.2 2.2 8.8 1.6 2.4 2 0 0 2 2 2 0 Flocculin type 3 repeat Linker_histone PF00538.19 CDS25607.1 - 3.3e-25 88.2 0.9 3.3e-25 88.2 0.9 2.4 2 1 0 2 2 2 1 linker histone H1 and H5 family Y_phosphatase PF00102.27 CDS25609.2 - 1.3e-64 218.0 0.0 2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDS25609.2 - 0.021 14.6 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cwf_Cwc_15 PF04889.12 CDS25609.2 - 3.3 7.4 33.2 0.03 14.0 17.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Striatin PF08232.12 CDS25610.1 - 7.5e-44 150.1 6.2 1.3e-43 149.3 6.2 1.4 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 CDS25610.1 - 7.1e-24 83.6 10.2 5.8e-06 27.0 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25610.1 - 0.00093 19.5 0.0 2.6 8.4 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Med14 PF08638.11 CDS25610.1 - 0.04 13.3 0.3 0.064 12.7 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit MED14 Nup160 PF11715.8 CDS25610.1 - 0.053 12.2 0.1 0.11 11.1 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4482 PF14818.6 CDS25610.1 - 0.79 10.6 10.7 0.58 11.0 7.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Dzip-like_N PF13815.6 CDS25612.1 - 2.2e-32 111.5 4.4 2.2e-32 111.5 4.4 3.3 3 1 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 CDS25612.1 - 0.0012 19.2 1.4 0.0012 19.2 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF3196 PF11428.8 CDS25612.1 - 0.0063 16.1 0.4 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3196) zf-C2H2_jaz PF12171.8 CDS25612.1 - 0.012 15.9 0.2 0.026 14.8 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDS25612.1 - 0.031 15.1 1.5 0.1 13.5 1.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 CDS25612.1 - 0.17 12.2 0.4 0.47 10.8 0.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LUC7 PF03194.15 CDS25612.1 - 6.8 6.3 14.9 1.7 8.3 2.1 3.6 3 0 0 3 3 3 0 LUC7 N_terminus Peptidase_M3 PF01432.20 CDS25613.1 - 1.7e-16 60.6 0.0 2.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 PAP2 PF01569.21 CDS25614.1 - 5.6e-23 81.2 4.5 9.1e-23 80.5 4.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CDS25614.1 - 0.00059 19.6 3.9 0.0011 18.7 3.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 CDS25614.1 - 0.0014 19.1 2.5 0.0014 19.1 2.5 1.7 2 0 0 2 2 2 1 PAP2 superfamily C-terminal TIP41 PF04176.13 CDS25615.1 - 1.5e-52 177.6 0.0 1.9e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family NIF PF03031.18 CDS25616.1 - 8.2e-39 132.9 0.0 1.2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EGF PF00008.27 CDS25617.1 - 3.4e-18 65.6 102.3 9.4e-09 35.4 3.1 9.2 9 1 0 9 9 9 6 EGF-like domain hEGF PF12661.7 CDS25617.1 - 3.4e-08 33.8 84.5 1.4e-06 28.7 1.8 9.6 9 1 0 9 9 9 4 Human growth factor-like EGF EGF_2 PF07974.13 CDS25617.1 - 4.7e-05 23.7 111.9 0.00028 21.2 10.8 9.0 7 2 1 8 8 8 5 EGF-like domain DSL PF01414.19 CDS25617.1 - 0.00022 21.4 5.3 0.00022 21.4 5.3 6.3 3 2 1 5 5 5 2 Delta serrate ligand EGF_MSP1_1 PF12946.7 CDS25617.1 - 0.043 13.9 0.3 0.043 13.9 0.3 7.1 7 0 0 7 7 7 0 MSP1 EGF domain 1 BTB PF00651.31 CDS25618.1 - 0.0015 18.7 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 CDS25619.1 - 0.0085 16.4 0.3 0.019 15.3 0.1 1.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDS25619.1 - 0.03 14.6 0.0 0.094 13.0 0.0 1.8 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CDS25619.1 - 0.11 12.1 0.8 1.3 8.7 0.1 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CDS25619.1 - 0.27 11.3 1.5 0.47 10.5 0.1 2.1 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CDS25620.2 - 7.7e-16 57.4 1.4 3.2e-07 29.8 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDS25620.2 - 3.7e-13 49.3 0.0 2.5e-06 27.6 0.0 3.7 2 1 1 3 3 3 2 Kelch motif BTB PF00651.31 CDS25620.2 - 1.4e-11 44.6 0.0 2.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDS25620.2 - 2e-07 31.0 0.2 4.2e-05 23.6 0.3 2.5 1 1 1 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDS25620.2 - 4.7e-06 26.4 0.0 0.0094 15.9 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CDS25620.2 - 2.7e-05 24.1 0.6 0.00048 20.1 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS25620.2 - 6e-05 22.9 0.1 0.022 14.7 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CDS25620.2 - 0.0013 18.9 0.0 0.056 13.8 0.0 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CDS25623.1 - 4.7e-23 80.5 0.1 8.5e-10 38.1 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDS25623.1 - 6.2e-16 58.1 0.1 1.5e-07 31.4 0.0 3.4 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CDS25623.1 - 2.3e-10 40.5 0.0 2.7e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS25623.1 - 1.2e-08 34.8 0.1 8.4e-07 28.9 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS25623.1 - 1.6e-06 27.9 0.1 0.00036 20.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CDS25623.1 - 2.8e-06 27.2 2.0 0.00073 19.5 0.0 3.8 5 0 0 5 5 5 1 Kelch motif BACK PF07707.15 CDS25623.1 - 0.00021 21.3 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch FCSD-flav_bind PF09242.11 CDS25623.1 - 0.059 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Bcl-2 PF00452.19 CDS25624.1 - 4.3e-15 56.2 0.0 9.5e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family Ephrin_rec_like PF07699.13 CDS25627.1 - 6e-05 22.7 11.6 0.00027 20.6 6.2 2.5 2 0 0 2 2 2 2 Putative ephrin-receptor like KRTDAP PF15200.6 CDS25627.1 - 0.031 14.1 11.5 22 4.9 0.2 7.3 7 1 0 7 7 7 0 Keratinocyte differentiation-associated CUE PF02845.16 CDS25627.1 - 0.048 13.4 0.1 3.5 7.4 0.0 3.2 3 0 0 3 3 3 0 CUE domain NCD3G PF07562.14 CDS25627.1 - 0.14 12.1 5.2 0.97 9.5 2.6 2.8 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TAP_C PF03943.13 CDS25628.1 - 4e-17 61.6 0.2 8.9e-17 60.5 0.2 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_8 PF13855.6 CDS25628.1 - 0.024 14.4 3.5 3.6 7.4 0.1 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CDS25628.1 - 0.064 13.8 1.4 29 5.8 0.2 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 CDS25628.1 - 0.073 13.5 6.5 0.88 10.1 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) ATP-synt_ab PF00006.25 CDS25629.1 - 5.9e-107 356.1 0.0 9.8e-107 355.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CDS25629.1 - 1.3e-42 144.5 0.0 2.6e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension TBP PF00352.21 CDS25629.1 - 3.3e-35 119.9 0.0 1.4e-17 63.4 0.1 2.9 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) ATP-synt_ab_N PF02874.23 CDS25629.1 - 3.2e-14 53.2 2.5 1e-13 51.6 2.5 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LPG_synthase_TM PF03706.13 CDS25630.1 - 0.013 15.0 8.6 0.022 14.3 8.6 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region CHCH PF06747.13 CDS25631.1 - 4.4e-06 26.7 0.7 8e-06 25.9 0.7 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CDS25631.1 - 5.5e-05 23.3 0.2 8.8e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type PurK_C PF17769.1 CDS25631.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain PH_13 PF16652.5 CDS25631.1 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain COX17 PF05051.13 CDS25631.1 - 0.089 13.2 1.2 0.18 12.2 1.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) PGAP1 PF07819.13 CDS25632.1 - 6.5e-55 186.4 0.0 1e-54 185.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein UCH PF00443.29 CDS25632.1 - 2.9e-24 86.0 0.0 7.1e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_6 PF12697.7 CDS25632.1 - 0.00092 19.9 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDS25632.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDS25632.1 - 0.034 13.8 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold UCH_1 PF13423.6 CDS25632.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Esterase PF00756.20 CDS25632.1 - 0.054 13.1 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 CDS25632.1 - 0.072 12.6 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Anoctamin PF04547.12 CDS25633.2 - 2.2e-147 491.5 9.1 2.7e-147 491.3 9.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CDS25633.2 - 2.8e-16 59.9 0.0 1.1e-10 41.7 0.0 2.7 2 1 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin PGF-CTERM PF18204.1 CDS25633.2 - 0.31 11.1 1.5 1.4 9.0 1.5 2.2 1 0 0 1 1 1 0 PGF-CTERM motif CENP-M PF11111.8 CDS25635.1 - 0.12 11.5 0.1 0.41 9.8 0.1 1.8 1 0 0 1 1 1 0 Centromere protein M (CENP-M) CS PF04969.16 CDS25636.1 - 5.3e-09 37.0 2.0 5.3e-09 37.0 2.0 1.8 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 CDS25636.1 - 1.9e-06 27.8 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. PIH1_CS PF18201.1 CDS25636.1 - 3.1e-05 24.3 0.0 6.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain KH_1 PF00013.29 CDS25637.2 - 8.4e-19 67.2 6.2 2.3e-11 43.3 0.1 2.7 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 CDS25637.2 - 0.0014 18.4 0.1 0.0036 17.1 0.0 1.6 2 0 0 2 2 2 1 KH domain KH_5 PF13184.6 CDS25637.2 - 0.21 11.7 0.4 0.45 10.6 0.1 1.7 2 0 0 2 2 2 0 NusA-like KH domain Methyltransf_34 PF11312.8 CDS25637.2 - 0.3 10.3 1.7 0.5 9.6 1.7 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DivIC PF04977.15 CDS25637.2 - 3.5 7.5 6.7 9.2 6.1 6.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 CDS25637.2 - 6.6 6.3 11.1 12 5.5 11.1 1.3 1 0 0 1 1 1 0 Spt20 family CIAPIN1 PF05093.13 CDS25638.1 - 2.1 8.9 0.0 2.1 8.9 0.0 3.5 3 1 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TSP_1 PF00090.19 CDS25639.1 - 6.2e-05 23.1 7.6 6.2e-05 23.1 7.6 3.0 2 0 0 2 2 2 1 Thrombospondin type 1 domain hEGF PF12661.7 CDS25639.1 - 7.2 7.4 26.2 0.33 11.6 2.8 5.5 4 1 0 4 4 4 0 Human growth factor-like EGF DNA_primase_lrg PF04104.14 CDS25640.1 - 1.7e-80 270.2 0.0 2.5e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pkinase PF00069.25 CDS25641.1 - 3.9e-59 200.2 0.0 4.6e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25641.1 - 5.7e-20 71.7 0.0 7.8e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS25641.1 - 8.9e-05 21.9 0.0 0.00046 19.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDS25641.1 - 0.00016 21.7 0.0 0.17 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS25641.1 - 0.01 14.6 0.0 0.02 13.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CDS25642.1 - 4.1e-52 177.1 0.0 5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25642.1 - 2.4e-11 43.4 0.0 6.8e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS25642.1 - 0.00081 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CDS25642.1 - 0.0029 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CDS25642.1 - 0.0037 16.6 0.1 0.0081 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS25642.1 - 0.017 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CDS25642.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CDS25642.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CH PF00307.31 CDS25643.1 - 6e-48 161.6 0.3 7e-25 87.3 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS25643.1 - 1.3e-06 28.1 0.1 0.0063 16.3 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain Phage_int_SAM_4 PF13495.6 CDS25643.1 - 0.03 14.8 1.1 14 6.2 0.0 3.7 5 0 0 5 5 5 0 Phage integrase, N-terminal SAM-like domain Ribonuc_2-5A PF06479.12 CDS25643.1 - 0.066 13.4 2.0 0.81 9.9 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease 2-5A AAA PF00004.29 CDS25645.1 - 1.1e-41 142.3 0.0 2.2e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CDS25645.1 - 4.4e-28 97.1 0.3 1.2e-27 95.6 0.3 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CDS25645.1 - 1.6e-21 76.1 2.4 1.6e-21 76.1 2.4 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CDS25645.1 - 5.6e-10 38.9 1.9 3.9e-09 36.2 0.0 3.1 4 0 0 4 4 3 1 AAA+ lid domain AAA_16 PF13191.6 CDS25645.1 - 9.2e-06 26.1 0.1 0.00093 19.6 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 CDS25645.1 - 1.9e-05 25.0 0.2 0.012 15.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 CDS25645.1 - 3.1e-05 23.3 0.0 6.6e-05 22.3 0.0 1.6 2 0 0 2 2 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CDS25645.1 - 3.7e-05 23.5 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDS25645.1 - 5e-05 23.3 0.1 0.00035 20.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDS25645.1 - 5.3e-05 23.2 0.0 0.00024 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDS25645.1 - 6.6e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDS25645.1 - 8.4e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CDS25645.1 - 0.00014 22.4 0.2 0.00052 20.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDS25645.1 - 0.00068 19.3 0.1 0.73 9.4 0.1 2.5 1 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDS25645.1 - 0.0023 18.3 0.1 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CDS25645.1 - 0.004 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDS25645.1 - 0.0048 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDS25645.1 - 0.0058 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CDS25645.1 - 0.018 14.5 0.0 0.059 12.8 0.0 1.9 2 1 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 CDS25645.1 - 0.019 14.3 0.0 6.1 6.1 0.0 2.4 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 CDS25645.1 - 0.023 14.1 0.0 0.063 12.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CDS25645.1 - 0.034 13.7 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDS25645.1 - 0.038 13.9 0.2 1.1 9.1 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 CDS25645.1 - 0.039 13.4 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 CDS25645.1 - 0.04 13.8 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 CDS25645.1 - 0.051 13.3 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CDS25645.1 - 0.055 13.2 0.0 0.91 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 CDS25645.1 - 0.065 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 CDS25645.1 - 0.17 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_30 PF13604.6 CDS25645.1 - 0.17 11.6 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDS25645.1 - 1.9 8.2 4.3 7.2 6.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain DUF1394 PF07159.12 CDS25646.1 - 4.3e-120 400.6 0.2 5e-120 400.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) APH PF01636.23 CDS25646.1 - 0.48 10.3 3.3 1.6 8.6 1.6 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ERM PF00769.19 CDS25648.1 - 8.6e-34 117.4 57.1 8.6e-34 117.4 57.1 2.9 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.10 CDS25648.1 - 1.3e-23 83.2 0.1 4.3e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDS25648.1 - 3.2e-20 72.7 0.0 3.2e-20 72.7 0.0 3.0 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDS25648.1 - 1.7e-08 34.3 0.0 7.1e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 FERM N-terminal domain DUF3258 PF11646.8 CDS25651.1 - 0.012 15.7 0.0 0.18 11.9 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF3258 PI3_PI4_kinase PF00454.27 CDS25653.1 - 5.1e-40 137.9 0.0 1.5e-39 136.3 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDS25653.1 - 1.5e-10 40.7 0.1 2.5e-09 36.8 0.0 2.8 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.6 CDS25653.1 - 0.062 13.8 2.4 0.071 13.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ASC PF00858.24 CDS25656.1 - 2e-05 23.8 0.7 3.2e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TMEM65 PF10507.9 CDS25657.1 - 3.3e-23 81.7 0.1 3.9e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 FAD_binding_3 PF01494.19 CDS25658.2 - 1.1e-06 28.1 0.1 2.2e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain LIM PF00412.22 CDS25658.2 - 1.4e-06 28.4 5.6 2.7e-06 27.5 5.6 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_2 PF00890.24 CDS25658.2 - 7e-05 22.1 0.1 0.00012 21.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3585 PF12130.8 CDS25658.2 - 0.00017 21.7 5.6 0.00017 21.7 5.6 1.9 2 0 0 2 2 1 1 Bivalent Mical/EHBP Rab binding domain Pyr_redox_2 PF07992.14 CDS25658.2 - 0.00036 19.9 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDS25658.2 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDS25658.2 - 0.0045 15.7 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.6 CDS25658.2 - 0.014 15.8 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CDS25658.2 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDS25658.2 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDS25658.2 - 0.039 13.2 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CAMSAP_CH PF11971.8 CDS25658.2 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain DZR PF12773.7 CDS25658.2 - 0.074 13.1 3.2 0.18 11.9 3.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Pyr_redox PF00070.27 CDS25658.2 - 0.075 13.6 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDS25658.2 - 0.1 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Thi4 family CH PF00307.31 CDS25658.2 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain FAD_oxidored PF12831.7 CDS25658.2 - 0.17 11.2 0.1 0.38 10.1 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDS25658.2 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4472 PF14739.6 CDS25658.2 - 0.56 11.0 8.5 0.12 13.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) F-box-like PF12937.7 CDS25659.2 - 6.3e-06 26.0 0.9 6.3e-06 26.0 0.9 3.2 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 CDS25659.2 - 0.0013 18.5 0.3 0.0043 16.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 CDS25659.2 - 0.09 12.4 0.1 0.27 10.8 0.1 1.9 1 0 0 1 1 1 0 F-box HTH_32 PF13565.6 CDS25661.1 - 0.0011 19.6 0.3 0.0026 18.3 0.3 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDS25661.1 - 0.022 14.8 0.2 0.042 13.9 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 CDS25661.1 - 0.038 14.1 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pox_MCEL PF03291.16 CDS25663.1 - 4.9e-72 242.8 0.0 8.1e-72 242.1 0.0 1.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CDS25663.1 - 4.8e-10 40.0 0.0 8.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS25663.1 - 2.1e-08 34.1 0.0 3.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS25663.1 - 6.5e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS25663.1 - 2.5e-06 28.0 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS25663.1 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDS25663.1 - 0.002 18.9 0.0 0.0048 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CDS25663.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Homeodomain PF00046.29 CDS25664.1 - 5.3e-12 45.4 0.7 1.3e-11 44.2 0.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS25664.1 - 7.6e-10 38.5 0.5 2.1e-09 37.2 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDS25664.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez zf-C2H2_4 PF13894.6 CDS25664.1 - 0.0077 17.0 2.0 2.2 9.3 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS25664.1 - 0.015 15.7 2.1 0.046 14.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDS25664.1 - 0.035 14.4 1.6 0.086 13.2 1.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PRP38_assoc PF12871.7 CDS25664.1 - 0.041 14.5 1.0 0.13 12.9 1.0 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2752 PF10825.8 CDS25664.1 - 0.11 12.6 0.2 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) dCMP_cyt_deam_1 PF00383.23 CDS25665.1 - 6.7e-27 93.3 0.0 9.7e-27 92.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDS25665.1 - 4.2e-13 49.2 0.0 5.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 CDS25665.1 - 0.0059 16.7 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase dCMP_cyt_deam_1 PF00383.23 CDS25666.1 - 1.1e-25 89.5 0.0 1.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDS25666.1 - 1.3e-12 47.7 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 CDS25666.1 - 0.023 14.8 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 CDS25666.1 - 0.058 13.5 1.2 0.1 12.8 0.3 1.8 2 1 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 CDS25666.1 - 4.8 7.2 5.2 12 6.0 0.1 2.5 2 1 1 3 3 3 0 Bd3614-like deaminase PrmA PF06325.13 CDS25667.1 - 3.4e-08 33.2 0.2 5.3e-08 32.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDS25667.1 - 9.5e-05 23.0 0.1 0.00023 21.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDS25667.1 - 0.0002 21.3 0.1 0.00035 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS25667.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.8 CDS25667.1 - 0.016 14.4 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 CDS25667.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 CDS25667.1 - 0.049 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 CDS25667.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YcaO PF02624.16 CDS25667.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding PCMT PF01135.19 CDS25667.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CDS25667.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CDS25667.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-RING_2 PF13639.6 CDS25668.1 - 9.7e-10 38.6 6.9 2.1e-09 37.6 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS25668.1 - 2.6e-09 36.8 7.7 4.9e-09 35.9 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS25668.1 - 8.3e-07 28.8 6.1 1.6e-06 27.9 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS25668.1 - 7.1e-05 22.6 5.3 0.00012 21.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS25668.1 - 0.00014 21.8 10.5 0.00027 20.9 10.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDS25668.1 - 0.0011 19.1 7.6 0.0035 17.6 7.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CDS25668.1 - 0.055 13.6 8.1 0.11 12.7 8.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1192 PF06698.11 CDS25668.1 - 0.13 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prok-RING_4 PF14447.6 CDS25668.1 - 0.4 10.6 10.9 0.76 9.7 4.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 CDS25668.1 - 0.9 9.8 5.4 2.7 8.3 5.4 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.5 CDS25668.1 - 1.7 8.8 8.7 0.19 11.9 3.7 2.0 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 CDS25668.1 - 1.8 8.6 6.0 3.7 7.6 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HEAT_EZ PF13513.6 CDS25669.1 - 3e-27 94.7 7.7 5.4e-10 39.6 0.0 10.9 10 1 2 12 12 11 4 HEAT-like repeat HEAT PF02985.22 CDS25669.1 - 2.7e-22 76.9 14.6 0.017 15.4 0.0 10.9 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 CDS25669.1 - 3.2e-17 62.7 0.0 0.014 15.8 0.0 7.0 3 3 3 6 6 6 6 HEAT repeats Cnd1 PF12717.7 CDS25669.1 - 2.7e-15 56.8 0.7 0.0032 17.5 0.0 4.7 3 2 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDS25669.1 - 1.1e-10 40.8 4.6 0.0016 17.1 0.1 4.7 3 2 1 4 4 4 3 Adaptin N terminal region IBN_N PF03810.19 CDS25669.1 - 4.4e-10 39.3 0.0 1.5e-08 34.4 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CDS25669.1 - 2.4e-09 37.7 0.9 0.37 11.4 0.2 6.8 6 2 2 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CDS25669.1 - 6.6e-08 32.4 0.1 0.18 11.3 0.0 5.1 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.23 CDS25669.1 - 9.3e-08 31.9 4.9 0.017 15.2 0.1 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 CDS25669.1 - 3.2e-05 23.9 0.6 3.2 7.6 0.0 5.6 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 CDS25669.1 - 0.00077 19.2 5.7 1.2 8.8 0.0 4.3 3 2 0 3 3 3 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 CDS25669.1 - 0.0062 15.7 7.3 0.45 9.6 0.0 5.2 3 2 1 6 6 6 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 CDS25669.1 - 0.0098 16.1 0.2 28 4.9 0.0 4.5 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 CDS25669.1 - 0.01 15.8 2.0 0.67 9.9 0.2 3.5 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 CDS25669.1 - 0.06 13.5 0.2 0.7 10.0 0.1 2.8 2 0 0 2 2 2 0 V-ATPase subunit H Telomere_reg-2 PF10193.9 CDS25669.1 - 0.39 11.2 1.8 1.7 9.1 0.2 2.8 2 0 0 2 2 2 0 Telomere length regulation protein Fcf2 PF08698.11 CDS25670.1 - 2.5e-20 72.7 0.3 2.5e-20 72.7 0.3 1.7 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Elongin_A PF06881.11 CDS25670.1 - 0.87 10.1 9.8 0.36 11.4 5.6 2.4 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NUDE_C PF04880.13 CDS25671.1 - 5.1e-18 66.2 4.9 5.1e-18 66.2 4.9 2.8 2 2 1 3 3 2 1 NUDE protein, C-terminal conserved region KASH_CCD PF14662.6 CDS25671.1 - 0.004 17.0 31.2 0.064 13.1 11.1 2.2 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 CDS25671.1 - 0.005 17.1 21.9 0.005 17.1 21.9 2.0 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 CDS25671.1 - 0.0064 16.1 20.3 0.0075 15.9 19.1 1.6 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Hist_deacetyl PF00850.19 CDS25671.1 - 0.02 14.4 0.2 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 Histone deacetylase domain PRKG1_interact PF15898.5 CDS25671.1 - 0.024 15.5 22.8 0.28 12.1 9.2 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain LPP PF04728.13 CDS25671.1 - 0.045 14.1 10.1 0.18 12.2 1.0 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Pox_A_type_inc PF04508.12 CDS25671.1 - 0.062 13.2 1.2 0.062 13.2 1.2 4.0 5 0 0 5 5 3 0 Viral A-type inclusion protein repeat GAT PF03127.14 CDS25671.1 - 0.067 13.5 8.0 0.13 12.6 2.5 3.0 1 1 1 2 2 2 0 GAT domain NPV_P10 PF05531.12 CDS25671.1 - 0.07 13.6 15.1 0.22 12.0 2.8 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TSKS PF15358.6 CDS25671.1 - 0.098 11.0 6.8 0.12 10.7 6.8 1.3 1 0 0 1 1 1 0 Testis-specific serine kinase substrate HAUS5 PF14817.6 CDS25671.1 - 0.11 11.3 18.8 0.62 8.8 1.7 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Cortex-I_coil PF09304.10 CDS25671.1 - 0.21 11.8 18.0 0.028 14.6 12.5 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil FlaC_arch PF05377.11 CDS25671.1 - 0.28 11.6 14.4 3.9 7.9 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 CDS25671.1 - 0.45 10.6 23.9 0.42 10.7 10.5 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Sigma54_AID PF00309.20 CDS25671.1 - 0.47 10.4 10.0 9.9 6.1 0.1 3.8 2 1 1 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) GAS PF13851.6 CDS25671.1 - 0.5 9.7 32.0 1.1 8.6 27.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CDS25671.1 - 0.58 10.2 11.0 0.23 11.5 4.4 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CDS25671.1 - 0.7 8.5 21.2 0.94 8.0 21.2 1.1 1 0 0 1 1 1 0 AAA domain PACT_coil_coil PF10495.9 CDS25671.1 - 0.76 10.4 3.3 2 9.0 0.3 2.4 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein UPF0242 PF06785.11 CDS25671.1 - 1.1 9.4 30.5 0.074 13.1 20.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 CDS25671.1 - 1.1 9.1 18.2 1.4 8.8 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5082 PF16888.5 CDS25671.1 - 1.7 8.9 18.4 0.57 10.5 9.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) SlyX PF04102.12 CDS25671.1 - 2.4 8.9 15.8 0.39 11.4 2.7 3.8 2 2 1 3 3 3 0 SlyX Macoilin PF09726.9 CDS25671.1 - 3.5 6.1 17.8 4.8 5.6 17.8 1.1 1 0 0 1 1 1 0 Macoilin family H-kinase_dim PF02895.14 CDS25671.1 - 4.1 7.9 11.9 31 5.1 2.6 4.3 2 1 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain TPR_MLP1_2 PF07926.12 CDS25671.1 - 4.3 7.4 31.5 2.6 8.1 12.8 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 CDS25671.1 - 4.6 7.3 15.6 5.2 7.1 9.2 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ARD PF03079.14 CDS25671.1 - 4.7 7.4 7.6 11 6.2 7.6 1.6 1 0 0 1 1 1 0 ARD/ARD' family HAP1_N PF04849.13 CDS25671.1 - 5.2 6.2 29.3 63 2.6 29.3 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region WD40_alt PF14077.6 CDS25671.1 - 5.2 7.0 12.0 2.9 7.8 0.1 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif CREPT PF16566.5 CDS25671.1 - 5.5 7.1 19.8 0.84 9.8 4.0 3.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Spc7 PF08317.11 CDS25671.1 - 6 5.7 25.6 0.96 8.3 20.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein IZUMO PF15005.6 CDS25671.1 - 8.5 6.9 10.4 4.9 7.6 7.4 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Exo_endo_phos PF03372.23 CDS25673.1 - 2.2e-15 56.8 0.0 3.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RING_9 PF13901.6 CDS25674.1 - 5.1e-35 121.3 31.0 4.1e-32 111.9 22.0 2.4 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon DUF2709 PF10915.8 CDS25674.1 - 0.082 12.2 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) NDUF_B5 PF09781.9 CDS25676.1 - 5.9e-30 104.2 0.7 6.7e-30 104.1 0.7 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Pkinase PF00069.25 CDS25677.1 - 2.2e-74 250.1 0.0 3.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25677.1 - 1.3e-44 152.5 0.0 2e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CDS25677.1 - 4.2e-14 52.1 0.0 7.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CDS25677.1 - 2.6e-08 33.5 0.0 8.2e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CDS25677.1 - 0.00086 19.0 0.6 0.0016 18.1 0.6 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDS25677.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA PF00627.31 CDS25677.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain RNA_pol_Rpb1_5 PF04998.17 CDS25678.2 - 1.2e-84 283.9 0.2 1.9e-84 283.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDS25678.2 - 1.6e-63 213.9 0.0 4e-63 212.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CDS25678.2 - 5.1e-56 190.3 0.0 7.8e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CDS25678.2 - 6.8e-40 136.6 0.0 4.2e-39 134.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDS25678.2 - 2.6e-24 85.3 0.0 6.4e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Shisa PF13908.6 CDS25679.2 - 1.8e-07 31.6 0.9 2e-07 31.5 0.9 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.16 CDS25679.2 - 0.011 14.5 0.2 0.013 14.3 0.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Tweety PF04906.13 CDS25679.2 - 0.035 12.8 4.6 0.042 12.5 4.6 1.1 1 0 0 1 1 1 0 Tweety EphA2_TM PF14575.6 CDS25679.2 - 0.12 13.2 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PROL5-SMR PF15621.6 CDS25679.2 - 1.1 9.8 7.8 1.9 9.1 7.8 1.5 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Prominin PF05478.11 CDS25679.2 - 1.3 6.9 12.1 1.5 6.7 12.1 1.0 1 0 0 1 1 1 0 Prominin TMEM52 PF14979.6 CDS25679.2 - 5.1 7.0 18.5 1 9.2 0.5 2.1 1 1 1 2 2 2 0 Transmembrane 52 NTS_2 PF15448.6 CDS25681.1 - 0.27 11.7 1.2 0.52 10.7 1.2 1.4 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Na_K-ATPase PF00287.18 CDS25682.1 - 3.8e-40 137.8 0.7 4.5e-40 137.6 0.7 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain TRAM PF01938.20 CDS25682.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 TRAM domain TPR_1 PF00515.28 CDS25683.1 - 1.3e-28 97.6 1.1 7e-09 35.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS25683.1 - 4e-24 84.0 1.5 2.1e-10 40.1 0.4 3.3 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 CDS25683.1 - 3.8e-22 76.5 0.3 1.9e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS25683.1 - 4.5e-15 54.5 2.7 0.00019 21.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 CDS25683.1 - 2.3e-11 43.3 0.1 7.2e-11 41.7 0.1 1.8 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_7 PF13176.6 CDS25683.1 - 3.8e-11 42.2 0.0 4e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS25683.1 - 4.1e-11 42.5 5.4 0.00014 22.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS25683.1 - 2.9e-09 37.1 0.5 4.1e-05 23.8 0.1 3.5 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS25683.1 - 1.7e-07 31.5 0.0 0.077 13.9 0.0 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDS25683.1 - 3.1e-07 29.7 2.1 0.052 13.0 0.1 4.0 4 0 0 4 4 4 2 SHNi-TPR TPR_9 PF13371.6 CDS25683.1 - 3.1e-06 27.2 0.0 0.00066 19.8 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS25683.1 - 5.2e-06 27.0 0.0 0.0045 17.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 CDS25683.1 - 2.8e-05 23.9 3.4 0.0016 18.2 0.1 3.5 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 CDS25683.1 - 0.00018 21.3 0.9 0.96 9.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS25683.1 - 0.0002 21.8 0.3 0.0039 17.7 0.0 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS25683.1 - 0.00035 20.6 2.2 1.2 9.3 0.1 3.4 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 CDS25683.1 - 0.00041 19.7 0.0 0.0026 17.0 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDS25683.1 - 0.0076 16.8 0.0 0.45 11.3 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF627 PF04781.12 CDS25683.1 - 0.083 12.9 0.6 0.75 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) RPN7 PF10602.9 CDS25683.1 - 0.12 12.1 0.1 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 XPC-binding PF09280.11 CDS25683.1 - 0.24 11.2 10.3 2.8 7.8 3.3 2.5 2 0 0 2 2 2 0 XPC-binding domain STI1 PF17830.1 CDS25683.1 - 5.2 7.1 11.5 0.62 10.0 2.0 2.6 2 0 0 2 2 2 0 STI1 domain APG17 PF04108.12 CDS25684.1 - 0.0025 17.0 0.3 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Med9 PF07544.13 CDS25684.1 - 0.059 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF5595 PF18077.1 CDS25684.1 - 0.1 12.7 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Rrp15p PF07890.12 CDS25685.1 - 1e-22 80.9 0.2 1.4e-22 80.5 0.2 1.2 1 0 0 1 1 1 1 Rrp15p IFT57 PF10498.9 CDS25686.1 - 1.2e-92 310.6 4.4 3.5e-92 309.2 4.4 1.6 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF773 PF05600.12 CDS25686.1 - 0.0029 16.4 2.2 0.0044 15.8 2.2 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Spc7 PF08317.11 CDS25686.1 - 0.012 14.5 7.3 0.018 13.9 7.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YkyA PF10368.9 CDS25686.1 - 0.023 14.4 6.3 0.043 13.5 6.3 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ARA70 PF12489.8 CDS25686.1 - 0.03 14.5 6.9 0.3 11.3 5.9 2.6 2 1 0 2 2 2 0 Nuclear coactivator Hrs_helical PF12210.8 CDS25686.1 - 0.046 14.3 4.2 0.13 12.8 0.9 2.6 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Transcrip_act PF04949.13 CDS25686.1 - 0.059 13.3 4.1 0.11 12.3 4.1 1.4 1 0 0 1 1 1 0 Transcriptional activator DUF1043 PF06295.12 CDS25686.1 - 0.084 12.9 5.4 4.3 7.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Peptidase_M3_N PF08439.10 CDS25686.1 - 0.15 12.3 4.0 0.13 12.5 0.5 2.5 2 0 0 2 2 2 0 Oligopeptidase F ARL2_Bind_BART PF11527.8 CDS25686.1 - 0.15 12.2 2.5 0.21 11.7 0.6 2.0 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART SpecificRecomb PF10136.9 CDS25686.1 - 0.18 10.1 1.9 0.24 9.7 1.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase MscS_porin PF12795.7 CDS25686.1 - 0.3 10.6 8.1 0.44 10.0 8.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain KELK PF15796.5 CDS25686.1 - 0.34 11.4 8.4 6.9 7.2 2.0 3.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec8_exocyst PF04048.14 CDS25686.1 - 0.34 10.8 2.6 1.2 9.1 0.4 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 CDS25686.1 - 0.43 10.6 4.9 1.3 9.0 4.9 1.9 1 0 0 1 1 1 0 Laminin Domain II DUF1640 PF07798.11 CDS25686.1 - 0.52 10.3 8.4 1.5 8.9 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) PRKG1_interact PF15898.5 CDS25686.1 - 0.75 10.7 8.7 9.8 7.1 7.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 CDS25686.1 - 0.81 9.0 4.7 1.9 7.8 4.5 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M TMPIT PF07851.13 CDS25686.1 - 1.3 8.2 4.7 2 7.6 4.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 CDS25686.1 - 1.8 9.2 9.8 0.53 10.9 1.8 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 CDS25686.1 - 2.8 7.8 11.6 2 8.3 0.4 3.4 2 1 1 3 3 3 0 Septum formation initiator RabGAP-TBC PF00566.18 CDS25688.1 - 5.9e-15 55.5 0.5 5e-14 52.5 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CDS25688.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Mhr1 PF12829.7 CDS25688.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination LRR_4 PF12799.7 CDS25689.2 - 1e-34 118.0 68.4 4.1e-08 33.4 1.4 8.1 2 1 10 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS25689.2 - 4.8e-23 81.5 21.0 6.6e-09 35.5 2.7 4.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CDS25689.2 - 4.6e-16 58.3 40.4 7.1e-07 28.9 0.9 6.8 3 2 1 5 5 5 4 Leucine rich repeat DUF1981 PF09324.10 CDS25689.2 - 1.3e-11 44.2 2.1 3e-08 33.4 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 CDS25689.2 - 5.2e-05 23.0 1.1 5.2e-05 23.0 1.1 4.0 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 LRR_6 PF13516.6 CDS25689.2 - 0.46 10.7 12.8 92 3.5 0.1 7.7 6 1 2 8 8 8 0 Leucine Rich repeat DUF3931 PF13082.6 CDS25690.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) E1_dh PF00676.20 CDS25693.1 - 1.4e-73 247.5 0.1 2e-73 247.0 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CDS25693.1 - 1.3e-60 204.1 0.0 2.7e-60 203.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDS25693.1 - 1.8e-50 170.6 0.0 3.2e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDS25693.1 - 4.6e-18 64.5 0.6 4.6e-18 64.5 0.6 2.8 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 CDS25693.1 - 0.038 13.9 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Phosphodiest PF01663.22 CDS25694.1 - 3.9e-14 53.0 1.9 8.7e-12 45.3 1.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDS25694.1 - 9.4e-10 38.4 0.2 0.00054 19.5 0.0 2.9 2 1 1 3 3 3 2 Sulfatase Metalloenzyme PF01676.18 CDS25694.1 - 0.00093 18.6 0.2 0.002 17.6 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily DnaJ PF00226.31 CDS25695.1 - 4.2e-28 97.3 0.9 7.1e-28 96.5 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain UCH PF00443.29 CDS25696.1 - 1.6e-37 129.4 0.0 3.6e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS25696.1 - 3.9e-23 82.5 1.3 8e-23 81.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CDS25696.1 - 7.3e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-FPG_IleRS PF06827.14 CDS25696.1 - 0.0038 17.1 0.2 0.015 15.1 0.2 2.1 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF1246 PF06849.12 CDS25696.1 - 0.0072 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) DUF1035 PF06281.12 CDS25696.1 - 0.27 11.3 0.8 1.7 8.7 0.8 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) FHA PF00498.26 CDS25697.1 - 1.4e-13 50.9 0.1 2.6e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 FHA domain Ribosomal_L32e PF01655.18 CDS25698.1 - 3.4e-45 152.9 4.0 3.9e-45 152.7 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 AraC_binding_2 PF14525.6 CDS25698.1 - 0.032 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AraC-binding-like domain FAP206 PF12018.8 CDS25699.1 - 6.4e-39 134.1 0.7 4e-38 131.5 0.0 2.5 4 0 0 4 4 4 1 Domain of unknown function Ribosomal_L27 PF01016.19 CDS25699.1 - 1.9e-06 27.8 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein YHS PF04945.13 CDS25699.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 YHS domain DotU PF09850.9 CDS25701.1 - 0.033 13.9 0.6 0.082 12.6 0.1 1.7 1 1 0 2 2 2 0 Type VI secretion system protein DotU NAD_Gly3P_dh_C PF07479.14 CDS25702.1 - 8e-46 155.8 0.1 1.4e-45 155.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CDS25702.1 - 1.3e-45 155.2 0.0 2.2e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RasGAP PF00616.19 CDS25703.1 - 1.7e-25 90.0 0.0 3.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase GST_C_3 PF14497.6 CDS25704.1 - 2.6e-10 40.4 0.4 4.5e-10 39.6 0.4 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS25704.1 - 3.4e-09 36.8 0.2 5.8e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS25704.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDS25704.1 - 0.0017 18.7 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS25704.1 - 0.0033 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sigma54_CBD PF04963.13 CDS25704.1 - 0.066 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Exo70 PF03081.15 CDS25705.1 - 2.2e-63 214.6 5.9 2.2e-63 214.6 5.9 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit phiKZ_IP PF12699.7 CDS25705.1 - 0.0063 15.7 0.7 0.071 12.3 0.0 2.7 2 1 0 2 2 2 1 phiKZ-like phage internal head proteins DASH_Dam1 PF08653.10 CDS25705.1 - 0.071 12.9 0.4 32 4.4 0.0 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 Cytochrom_B562 PF07361.11 CDS25705.1 - 0.56 10.9 3.0 1.4 9.6 0.2 3.1 3 0 0 3 3 3 0 Cytochrome b562 DUF1664 PF07889.12 CDS25705.1 - 0.99 9.5 3.6 0.71 9.9 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 CDS25705.1 - 1.7 8.0 11.2 3.3 7.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.22 CDS25705.1 - 3.3 8.0 5.6 6.6 7.0 0.3 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 CDS25705.1 - 5.2 7.1 8.3 1.2 9.3 0.3 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reticulon PF02453.17 CDS25706.1 - 6.1e-37 127.0 3.2 7.3e-37 126.8 3.2 1.1 1 0 0 1 1 1 1 Reticulon UL45 PF05473.12 CDS25706.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like PAP2 PF01569.21 CDS25706.1 - 1.1 9.0 11.1 0.22 11.3 1.5 2.1 2 0 0 2 2 2 0 PAP2 superfamily Pex24p PF06398.11 CDS25706.1 - 1.8 7.5 8.8 0.96 8.4 0.7 2.0 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin AA_permease PF00324.21 CDS25707.2 - 5.1e-64 216.6 45.3 7e-64 216.2 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CDS25707.2 - 9.4e-09 34.8 0.0 1.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 F5_F8_type_C PF00754.25 CDS25708.1 - 5.6e-07 29.7 0.0 6.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Laminin_N PF00055.17 CDS25708.1 - 0.017 14.8 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) NOG1_N PF17835.1 CDS25709.1 - 0.016 15.2 0.7 0.18 11.8 0.0 2.6 2 1 0 2 2 2 0 NOG1 N-terminal helical domain DUF1981 PF09324.10 CDS25709.1 - 0.039 13.8 0.2 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Gliadin PF13016.6 CDS25709.1 - 0.24 11.8 3.3 0.21 12.0 0.5 2.4 3 0 0 3 3 3 0 Cys-rich Gliadin N-terminal IZUMO PF15005.6 CDS25709.1 - 0.66 10.5 6.2 3 8.3 0.6 2.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SET PF00856.28 CDS25710.1 - 1e-10 42.3 0.0 2.4e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 CDS25710.1 - 1.5e-05 24.7 0.2 0.043 13.9 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS25710.1 - 0.00067 19.9 0.9 0.076 13.3 0.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS25710.1 - 0.0034 17.1 1.6 2.6 8.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Meleagrin PF08189.11 CDS25710.1 - 0.03 14.0 0.6 0.03 14.0 0.6 2.6 2 0 0 2 2 2 0 Meleagrin/Cygnin family Peptidase_M16_C PF05193.21 CDS25711.1 - 1.6e-38 132.6 0.0 4.7e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDS25711.1 - 1.7e-23 83.3 0.0 4.3e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Glyco_hydro_65m PF03632.15 CDS25713.1 - 4.7e-46 157.4 0.3 2.5e-40 138.5 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Claudin_3 PF06653.11 CDS25715.1 - 0.00092 19.2 7.3 0.00092 19.2 7.3 1.7 1 1 1 2 2 2 1 Tight junction protein, Claudin-like DUF2127 PF09900.9 CDS25715.1 - 0.0038 17.5 0.8 0.0038 17.5 0.8 1.9 3 0 0 3 3 3 1 Predicted membrane protein (DUF2127) 7TM_GPCR_Srv PF10323.9 CDS25717.1 - 0.0012 18.3 2.5 0.0012 18.3 2.5 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Myc_target_1 PF15179.6 CDS25717.1 - 0.094 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Myc target protein 1 PsbL PF02419.17 CDS25717.1 - 0.16 11.9 5.2 1.3 9.1 1.2 2.7 2 0 0 2 2 2 0 PsbL protein Gaa1 PF04114.14 CDS25717.1 - 0.29 10.1 7.7 0.38 9.7 7.7 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF2207 PF09972.9 CDS25717.1 - 1.3 7.8 18.8 1.5 7.5 2.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 CDS25717.1 - 1.6 6.9 14.9 2 6.6 14.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CrgA PF06781.12 CDS25717.1 - 3.6 7.7 9.9 0.12 12.5 2.2 2.3 2 1 1 3 3 3 0 Cell division protein CrgA TMEM192 PF14802.6 CDS25717.1 - 4.7 6.2 8.5 0.51 9.4 1.9 1.9 1 1 1 2 2 2 0 TMEM192 family Tmemb_55A PF09788.9 CDS25717.1 - 5.5 6.0 5.8 1.2 8.2 2.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 55A MpPF26 PF07666.11 CDS25717.1 - 6.1 7.0 20.4 11 6.2 14.4 2.8 1 1 2 3 3 3 0 M penetrans paralogue family 26 Abhydrolase_9_N PF15420.6 CDS25717.1 - 7 6.6 10.6 8.9 6.3 7.6 1.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus RNase_T PF00929.24 CDS25718.1 - 3.9e-05 24.3 0.1 8e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 CDS25718.1 - 0.00017 21.9 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 DNA_pol_A_exo1 PF01612.20 CDS25718.1 - 0.00099 18.9 0.7 0.0019 18.0 0.7 1.5 1 1 0 1 1 1 1 3'-5' exonuclease DUF3602 PF12223.8 CDS25718.1 - 5.5 7.7 6.8 32 5.2 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3602) RVT_1 PF00078.27 CDS25719.1 - 3.2e-08 33.4 0.0 3.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arteri_nsp7a PF16749.5 CDS25719.1 - 0.031 14.4 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Rhamno_transf PF11316.8 CDS25719.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF2024 PF09630.10 CDS25719.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) DUF2959 PF11172.8 CDS25719.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Arg_repressor_C PF02863.18 CDS25720.2 - 0.08 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain RNase_T PF00929.24 CDS25723.2 - 2.2e-06 28.3 0.0 4.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CDS25723.2 - 0.00078 19.2 0.4 0.0017 18.1 0.4 1.7 1 1 0 1 1 1 1 3'-5' exonuclease EloA-BP1 PF15870.5 CDS25723.2 - 0.0012 19.1 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 ElonginA binding-protein 1 Y_phosphatase PF00102.27 CDS25724.1 - 2.7e-153 508.3 0.6 3.9e-76 255.7 0.1 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDS25724.1 - 4.9e-08 33.2 0.0 0.00067 19.7 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 CDS25724.1 - 2.3e-07 30.7 0.0 0.0068 16.2 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS25724.1 - 4.8e-05 23.5 0.1 0.3 11.2 0.0 3.1 3 0 0 3 3 3 2 Inositol hexakisphosphate ASC PF00858.24 CDS25726.2 - 6.1e-11 41.9 0.1 4.4e-09 35.8 0.1 2.4 2 1 0 2 2 2 2 Amiloride-sensitive sodium channel Phage_Coat_A PF05357.13 CDS25727.2 - 0.18 11.7 7.5 0.37 10.6 2.8 2.5 2 0 0 2 2 2 0 Phage Coat Protein A PCI PF01399.27 CDS25728.1 - 2.7e-12 47.1 0.0 6.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 CDS25728.1 - 2.1e-08 33.7 2.3 3.7e-08 32.9 2.3 1.4 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix dsrm PF00035.26 CDS25729.1 - 1e-18 67.8 2.8 1.9e-10 41.3 0.3 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CDS25729.1 - 1.2e-05 25.4 1.0 0.43 10.8 0.0 3.8 3 1 0 3 3 3 2 Dicer dimerisation domain DND1_DSRM PF14709.7 CDS25729.1 - 0.00017 21.7 8.3 0.11 12.8 1.6 4.5 3 2 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Mpp10 PF04006.12 CDS25730.1 - 1.7e-42 145.7 8.2 1.9e-42 145.6 8.2 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF4479 PF14794.6 CDS25730.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Corona_NS1 PF06145.11 CDS25730.1 - 0.11 12.1 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 DUF2048 PF09752.9 CDS25731.1 - 7.6e-94 314.7 0.0 1e-93 314.3 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 CDS25731.1 - 1.1e-05 26.2 1.8 6.2e-05 23.7 1.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CDS25731.1 - 0.018 14.7 0.6 0.044 13.4 0.6 1.7 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 CDS25731.1 - 0.073 13.2 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Thioesterase domain Fzo_mitofusin PF04799.13 CDS25731.1 - 0.2 11.2 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Dynein_light PF01221.18 CDS25732.1 - 9e-39 131.7 1.2 1e-38 131.5 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 CDS25732.1 - 0.023 14.5 0.1 0.029 14.2 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 48 PBAN PF05874.11 CDS25734.1 - 0.072 13.0 0.7 0.1 12.5 0.7 1.2 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Nucleoside_tran PF01733.18 CDS25735.1 - 1.3e-34 120.0 17.7 2.1e-33 116.1 17.7 2.1 1 1 0 1 1 1 1 Nucleoside transporter IML1 PF12257.8 CDS25736.1 - 4e-63 213.2 0.1 1e-62 211.9 0.1 1.6 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 LRR_8 PF13855.6 CDS25736.1 - 2.8e-15 55.8 27.0 1.2e-09 37.7 10.2 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CDS25736.1 - 8.2e-06 26.1 32.4 0.0013 19.1 4.5 5.4 2 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS25736.1 - 6.3e-05 22.5 1.5 0.00013 21.5 1.5 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 CDS25736.1 - 0.00053 20.0 2.3 0.65 10.0 0.1 3.0 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Adeno_E3_CR2 PF02439.15 CDS25736.1 - 0.038 13.8 1.7 0.077 12.8 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_1 PF00560.33 CDS25736.1 - 0.2 12.3 16.8 30 5.7 0.8 6.9 6 0 0 6 6 6 0 Leucine Rich Repeat DEP PF00610.21 CDS25737.1 - 2.7e-08 33.7 0.0 6.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 CDS25738.1 - 2.4e-44 151.7 0.0 2.3e-27 96.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25738.1 - 3.7e-14 52.6 0.0 2.5e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDS25738.1 - 3.4e-06 27.1 0.0 0.0021 18.0 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS25738.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDS25738.1 - 0.011 15.4 0.0 0.21 11.2 0.1 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDS25738.1 - 0.033 13.5 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like ART PF01129.18 CDS25738.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DivIVA PF05103.13 CDS25738.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 DivIVA protein Amidohydro_1 PF01979.20 CDS25739.1 - 4.9e-29 101.7 0.3 8.3e-29 101.0 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDS25739.1 - 1.4e-09 38.0 0.3 0.00015 21.4 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 CDS25739.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CDS25740.1 - 5.5e-12 45.7 0.0 9.8e-10 38.3 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CDS25740.1 - 3.6e-11 43.2 0.1 2.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 CDS25740.1 - 0.038 14.3 2.4 0.063 13.6 1.6 1.8 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain AAA_6 PF12774.7 CDS25741.1 - 1.4e-155 517.2 0.2 8.7e-151 501.5 0.0 4.9 4 1 1 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CDS25741.1 - 2.4e-129 432.5 14.2 2.4e-129 432.5 14.2 3.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 CDS25741.1 - 1.4e-121 405.8 13.2 2.6e-121 404.9 13.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DHC_N2 PF08393.13 CDS25741.1 - 4.4e-100 335.6 21.0 4.4e-100 335.6 21.0 4.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CDS25741.1 - 3.5e-97 324.8 0.1 1.6e-96 322.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDS25741.1 - 5.1e-91 305.1 0.1 3.1e-90 302.5 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDS25741.1 - 1.1e-80 270.0 2.0 4.4e-80 267.9 2.0 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS25741.1 - 1.7e-69 232.9 1.7 1.5e-64 216.9 0.4 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS25741.1 - 1.6e-53 180.9 0.0 6.3e-53 178.9 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDS25741.1 - 6.6e-37 126.2 0.0 8e-36 122.7 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CDS25741.1 - 1.2e-28 99.2 0.2 6.7e-28 96.8 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDS25741.1 - 8.4e-26 90.6 2.4 5.4e-25 87.9 2.4 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDS25741.1 - 9.5e-24 84.0 0.4 2.9e-09 37.0 0.0 5.7 6 1 0 6 6 4 4 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS25741.1 - 1.3e-05 25.7 1.5 0.38 11.1 0.0 5.9 6 1 1 7 7 4 1 AAA ATPase domain AAA_18 PF13238.6 CDS25741.1 - 3.7e-05 24.3 0.3 3 8.4 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 CDS25741.1 - 3.9e-05 23.9 0.0 6.4 7.1 0.0 4.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CDS25741.1 - 0.0004 20.2 1.7 2.8 7.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CDS25741.1 - 0.0012 19.2 0.3 1.4 9.3 0.0 3.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDS25741.1 - 0.0024 17.6 3.0 7.1 6.3 0.0 5.4 6 0 0 6 6 6 0 AAA domain DUF2075 PF09848.9 CDS25741.1 - 0.0024 17.2 0.0 0.69 9.1 0.0 2.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 CDS25741.1 - 0.0029 17.3 0.0 2.3 7.9 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CDS25741.1 - 0.01 16.2 0.1 11 6.5 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 CDS25741.1 - 0.02 15.0 0.7 33 4.6 0.0 4.4 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 CDS25741.1 - 0.024 15.1 0.1 27 5.2 0.0 4.2 3 0 0 3 3 2 0 ABC transporter Utp12 PF04003.12 CDS25741.1 - 0.024 14.9 0.0 1.4 9.2 0.0 3.3 2 0 0 2 2 2 0 Dip2/Utp12 Family AAA_19 PF13245.6 CDS25741.1 - 0.037 14.4 2.2 11 6.3 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CDS25741.1 - 0.049 13.2 0.2 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CDS25741.1 - 0.077 12.8 0.0 0.077 12.8 0.0 4.8 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 CDS25741.1 - 0.11 12.2 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF4140 PF13600.6 CDS25741.1 - 0.29 11.6 7.4 0.55 10.7 0.0 3.8 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) GIT_CC PF16559.5 CDS25741.1 - 0.44 10.5 2.4 2.1 8.3 0.2 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor BSMAP PF12280.8 CDS25741.1 - 0.59 10.3 2.7 7.2 6.8 0.0 2.9 2 0 0 2 2 2 0 Brain specific membrane anchored protein DUF948 PF06103.11 CDS25741.1 - 5.6 7.3 9.4 32 4.9 2.5 4.4 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) QVR PF17064.5 CDS25742.1 - 0.026 14.8 1.9 0.42 10.9 0.2 2.2 1 1 1 2 2 2 0 Sleepless protein Hus1 PF04005.12 CDS25743.1 - 2.4e-54 184.5 0.0 3.8e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Hus1-like protein BRCT_2 PF16589.5 CDS25743.1 - 2.9e-12 46.8 0.0 3.9e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDS25743.1 - 5.2e-10 39.6 0.0 1.4e-05 25.4 0.0 3.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDS25743.1 - 5.5e-07 29.4 0.2 5.7e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 CDS25743.1 - 5.4e-05 23.4 0.1 0.0012 19.1 0.0 2.8 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain I-set PF07679.16 CDS25744.1 - 6.5e-57 189.6 0.0 2.1e-13 50.1 0.0 5.1 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS25744.1 - 3.6e-34 117.2 0.0 1.8e-06 28.4 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 CDS25744.1 - 7.1e-23 80.8 0.0 0.0012 19.1 0.0 5.6 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 CDS25744.1 - 4.3e-19 68.7 0.1 0.0049 17.0 0.0 6.3 5 2 0 5 5 5 5 Immunoglobulin V-set domain ig PF00047.25 CDS25744.1 - 2e-18 66.3 0.0 0.0008 19.5 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain Receptor_2B4 PF11465.8 CDS25744.1 - 0.00098 19.3 0.6 7.8 6.8 0.0 4.2 5 0 0 5 5 5 2 Natural killer cell receptor 2B4 MBG PF17883.1 CDS25744.1 - 0.044 14.4 0.6 0.5 11.0 0.0 2.9 3 0 0 3 3 3 0 MBG domain DUF2012 PF09430.10 CDS25744.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) fn3 PF00041.21 CDS25745.2 - 0 1735.6 93.0 8.6e-19 67.7 0.2 37.9 37 0 0 37 37 37 37 Fibronectin type III domain I-set PF07679.16 CDS25745.2 - 0 1182.6 0.0 1.6e-18 66.5 0.0 32.8 32 0 0 32 32 31 29 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS25745.2 - 1.1e-213 692.5 3.2 3.7e-13 49.9 0.0 32.1 32 0 0 32 32 31 25 Immunoglobulin domain Pkinase PF00069.25 CDS25745.2 - 8.7e-123 408.8 0.0 4.2e-60 203.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain ig PF00047.25 CDS25745.2 - 2.1e-101 332.3 22.8 4.2e-09 36.5 0.1 24.0 25 0 0 25 25 22 13 Immunoglobulin domain Ig_2 PF13895.6 CDS25745.2 - 3.8e-101 331.6 11.4 2.6e-10 40.5 0.0 29.6 30 0 0 30 30 30 13 Immunoglobulin domain Pkinase_Tyr PF07714.17 CDS25745.2 - 1.8e-61 207.7 0.0 2e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase V-set PF07686.17 CDS25745.2 - 1.4e-56 189.4 29.0 8.1e-07 29.2 0.0 27.3 23 7 3 26 26 24 7 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 CDS25745.2 - 6.3e-44 148.5 41.6 0.003 18.1 0.1 29.8 34 2 0 34 34 27 6 Purple acid Phosphatase, N-terminal domain C2-set_2 PF08205.12 CDS25745.2 - 4.1e-20 71.6 17.2 0.16 12.1 0.0 15.5 17 0 0 17 17 15 2 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 CDS25745.2 - 1.5e-19 69.9 0.0 14 6.0 0.0 18.5 21 0 0 21 21 17 0 Fibronectin type III domain Ig_6 PF18452.1 CDS25745.2 - 1.8e-19 69.0 7.1 0.0023 17.5 0.0 10.2 12 0 0 12 12 9 2 Immunoglobulin domain fn3_4 PF16794.5 CDS25745.2 - 5e-19 68.1 0.0 0.64 10.0 0.0 15.7 15 0 0 15 15 14 3 Fibronectin-III type domain Y_Y_Y PF07495.13 CDS25745.2 - 8.2e-18 64.1 5.0 4.9 7.2 0.0 16.7 19 0 0 19 19 14 1 Y_Y_Y domain Ig_5 PF16681.5 CDS25745.2 - 1.2e-15 57.7 13.5 0.35 11.3 0.1 11.0 11 0 0 11 11 10 4 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain BiPBP_C PF06832.12 CDS25745.2 - 6.6e-15 54.9 4.2 0.24 11.4 0.0 12.0 13 0 0 13 13 12 3 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.8 CDS25745.2 - 5.3e-13 49.1 5.4 17 5.7 0.0 14.7 16 0 0 16 16 14 0 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 CDS25745.2 - 7.7e-12 45.1 7.4 4.5 7.4 0.0 10.7 11 0 0 11 11 9 3 Izumo-like Immunoglobulin domain DUF2369 PF10179.9 CDS25745.2 - 3.9e-11 43.2 0.0 75 3.8 0.0 13.8 17 0 0 17 17 15 0 Uncharacterised conserved protein (DUF2369) Ig_4 PF16680.5 CDS25745.2 - 1.8e-10 40.9 18.9 2.5 8.5 0.1 10.7 12 0 0 12 12 9 3 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 CDS25745.2 - 2.5e-10 40.6 11.6 0.65 10.4 0.0 10.2 11 0 0 11 11 10 1 Immunoglobulin C1-set domain Ig_C17orf99 PF17736.1 CDS25745.2 - 1.2e-06 28.4 0.0 0.97 9.5 0.0 5.5 5 0 0 5 5 5 2 C17orf99 Ig domain YrbL-PhoP_reg PF10707.9 CDS25745.2 - 2.2e-06 27.4 0.2 0.13 11.8 0.1 3.1 4 0 0 4 4 4 2 PhoP regulatory network protein YrbL Glyco_hydro38C2 PF17677.1 CDS25745.2 - 2.3e-06 27.6 1.0 0.15 12.2 0.1 3.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal beta sandwich domain FTA2 PF13095.6 CDS25745.2 - 0.00013 21.7 0.6 1.5 8.4 0.0 3.2 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Herpes_gE PF02480.16 CDS25745.2 - 0.00064 18.6 0.0 3.2 6.4 0.0 4.0 4 0 0 4 4 4 2 Alphaherpesvirus glycoprotein E Seadorna_VP7 PF07387.11 CDS25745.2 - 0.00082 18.5 1.5 0.85 8.6 0.1 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 PKD_3 PF16820.5 CDS25745.2 - 0.0021 17.8 3.2 9.2 6.1 0.0 5.6 5 0 0 5 5 5 0 PKD-like domain bMG6 PF17962.1 CDS25745.2 - 0.0022 18.1 0.4 2.1e+02 2.1 0.0 9.3 9 0 0 9 9 5 0 Bacterial macroglobulin domain 6 Kdo PF06293.14 CDS25745.2 - 0.022 14.1 0.0 7.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT PF03061.22 CDS25745.2 - 0.1 13.0 0.1 31 5.0 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily APH PF01636.23 CDS25745.2 - 0.11 12.4 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4179 PF13786.6 CDS25745.2 - 0.21 12.1 0.4 39 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) V-set_CD47 PF08204.11 CDS25745.2 - 0.26 11.3 9.7 20 5.2 0.1 5.9 5 0 0 5 5 5 0 CD47 immunoglobulin-like domain DUF4232 PF14016.6 CDS25745.2 - 0.42 10.8 38.5 1.1 9.3 1.0 10.6 10 0 0 10 10 10 0 Protein of unknown function (DUF4232) Adhesin_P1 PF03257.13 CDS25745.2 - 1.5 9.4 4.3 7.5 7.1 0.0 3.6 4 0 0 4 4 2 0 Mycoplasma adhesin P1 Ras PF00071.22 CDS25747.1 - 2.9e-52 176.5 0.0 3.4e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS25747.1 - 1.6e-20 73.5 0.0 2.3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS25747.1 - 8.4e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS25747.1 - 5.8e-06 26.0 0.2 1.8e-05 24.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS25747.1 - 5.8e-05 23.0 0.0 0.083 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CDS25747.1 - 0.00019 21.3 0.1 0.0081 16.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CDS25747.1 - 0.00065 19.2 0.1 0.0048 16.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDS25747.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CDS25747.1 - 0.053 13.1 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDS25747.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 CDS25747.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 CDS25747.1 - 0.19 10.9 0.2 0.25 10.5 0.2 1.4 1 1 0 1 1 1 0 NB-ARC domain PX PF00787.24 CDS25748.1 - 1e-14 54.5 0.4 1e-14 54.5 0.4 2.5 3 0 0 3 3 3 1 PX domain Cyt-b5 PF00173.28 CDS25750.1 - 5.1e-20 71.4 0.1 9.4e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-SNARE_C PF12352.8 CDS25750.1 - 1.3e-11 44.6 2.6 1.3e-11 44.6 2.6 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDS25750.1 - 0.003 17.4 3.3 0.014 15.3 0.1 2.7 2 1 1 3 3 3 1 Sec20 RRN3 PF05327.11 CDS25751.1 - 5.4e-25 88.0 4.9 2e-23 82.8 4.9 2.0 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Band_7 PF01145.25 CDS25752.1 - 3.6e-29 102.0 0.1 6.3e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CDS25752.1 - 4.9e-23 81.0 2.3 7.1e-23 80.4 1.0 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CDS25752.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Robl_LC7 PF03259.17 CDS25752.1 - 0.12 12.1 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Roadblock/LC7 domain HMG-CoA_red PF00368.18 CDS25755.1 - 4.8e-132 440.4 0.1 6.1e-132 440.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S5 PF00333.20 CDS25756.2 - 9.6e-33 112.0 8.1 7e-16 58.0 1.0 2.3 2 0 0 2 2 2 2 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDS25756.2 - 4.7e-30 102.9 0.0 2e-15 56.0 0.0 2.9 2 0 0 2 2 2 2 Ribosomal protein S5, C-terminal domain RabGAP-TBC PF00566.18 CDS25757.1 - 6.9e-46 156.6 0.6 1.8e-45 155.3 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RUN PF02759.19 CDS25757.1 - 1.2e-28 99.8 0.2 4.7e-28 97.8 0.1 2.1 2 0 0 2 2 2 1 RUN domain SH3_1 PF00018.28 CDS25757.1 - 1.5e-12 46.9 0.0 3e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS25757.1 - 2.4e-09 36.9 0.0 5.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS25757.1 - 7.1e-07 28.8 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GTF2I PF02946.14 CDS25757.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 GTF2I-like repeat OAD_gamma PF04277.13 CDS25761.1 - 0.026 15.1 0.0 0.031 14.8 0.0 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PBP_sp32 PF07222.12 CDS25761.1 - 0.089 12.2 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Paramecium_SA PF01508.16 CDS25761.1 - 0.97 9.9 6.0 8.4 6.9 6.0 2.0 1 1 0 1 1 1 0 Paramecium surface antigen domain Dicty_spore_N PF04562.12 CDS25762.1 - 0.012 16.3 6.8 0.012 16.3 6.8 1.8 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus Bac_A_amyl_C PF18612.1 CDS25762.1 - 0.087 12.6 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain ANATO PF01821.18 CDS25762.1 - 0.17 12.8 1.1 0.17 12.8 1.1 2.3 2 0 0 2 2 2 0 Anaphylotoxin-like domain G-patch PF01585.23 CDS25765.1 - 6.1e-13 48.4 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS25765.1 - 1.8e-05 24.7 0.1 1.8e-05 24.7 0.1 2.2 3 0 0 3 3 3 1 G-patch domain ATP19 PF11022.8 CDS25765.1 - 0.075 13.4 2.5 0.096 13.1 1.7 1.8 2 1 0 2 2 2 0 ATP synthase subunit K JHBP PF06585.11 CDS25766.1 - 0.42 9.8 7.0 1.2 8.2 0.1 4.6 5 1 1 6 6 6 0 Haemolymph juvenile hormone binding protein (JHBP) Prefoldin_2 PF01920.20 CDS25767.1 - 5.6e-17 61.6 16.6 8.4e-17 61.1 16.0 1.6 1 1 1 2 2 2 2 Prefoldin subunit Elf4 PF07011.11 CDS25767.1 - 0.0099 15.8 4.9 0.067 13.1 0.2 2.3 2 0 0 2 2 2 1 Early Flowering 4 domain DUF2164 PF09932.9 CDS25767.1 - 0.011 15.8 1.3 0.039 14.0 0.1 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) GP41 PF00517.17 CDS25767.1 - 0.02 14.8 3.4 0.024 14.5 3.4 1.2 1 0 0 1 1 1 0 Retroviral envelope protein RmuC PF02646.16 CDS25767.1 - 0.026 13.7 0.7 0.026 13.7 0.7 2.0 2 0 0 2 2 2 0 RmuC family DUF4407 PF14362.6 CDS25767.1 - 0.031 13.6 6.9 0.038 13.3 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CDS25767.1 - 0.067 12.1 16.0 0.087 11.7 16.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Vac_Fusion PF02346.16 CDS25767.1 - 0.12 12.0 5.3 0.26 10.9 1.4 2.6 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF1664 PF07889.12 CDS25767.1 - 0.13 12.3 10.2 2 8.5 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 CDS25767.1 - 0.19 11.7 16.6 23 4.9 16.6 3.2 1 1 0 1 1 1 0 Prefoldin subunit APG6_N PF17675.1 CDS25767.1 - 0.21 12.1 16.8 0.5 10.9 15.0 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region NRBF2_MIT PF17169.4 CDS25767.1 - 0.46 10.7 8.0 1.4 9.2 2.7 2.4 1 1 1 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 KxDL PF10241.9 CDS25767.1 - 0.48 10.7 12.0 1.3 9.3 6.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein IZUMO PF15005.6 CDS25767.1 - 0.5 10.9 8.9 1.2 9.7 8.9 1.6 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated ING PF12998.7 CDS25767.1 - 1.1 9.9 12.4 0.99 10.0 2.6 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.10 CDS25767.1 - 1.6 8.9 16.9 4.2 7.5 3.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 CDS25767.1 - 2.3 8.3 10.4 0.4 10.8 1.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 CDS25767.1 - 2.6 7.7 11.4 0.21 11.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CCDC-167 PF15188.6 CDS25767.1 - 2.7 8.4 11.0 15 6.0 10.3 2.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TMF_DNA_bd PF12329.8 CDS25767.1 - 6.6 6.8 17.8 4.5 7.4 2.4 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nup88 PF10168.9 CDS25767.1 - 6.9 4.3 14.2 16 3.1 13.6 1.6 1 1 0 1 1 1 0 Nuclear pore component Vir_act_alpha_C PF10400.9 CDS25767.1 - 7.6 7.3 10.0 4.9 7.9 3.7 2.4 1 1 1 2 2 2 0 Virulence activator alpha C-term Rho_Binding PF08912.11 CDS25767.1 - 8.8 7.2 17.1 6.1 7.7 5.3 2.6 2 1 0 2 2 2 0 Rho Binding RRM_1 PF00076.22 CDS25768.1 - 1.3e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CDS25768.1 - 0.00015 22.5 0.4 0.00068 20.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_occluded PF16842.5 CDS25768.1 - 0.00065 19.5 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF445 PF04286.12 CDS25768.1 - 0.035 13.9 1.2 0.063 13.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Med9 PF07544.13 CDS25768.1 - 0.14 12.3 1.6 0.3 11.2 0.7 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prenyltransf PF01255.19 CDS25769.1 - 4.4e-36 124.5 0.1 5.8e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pkinase_Tyr PF07714.17 CDS25770.1 - 2.7e-85 285.8 0.0 5e-85 284.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25770.1 - 1.2e-44 152.7 0.0 1.9e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS25770.1 - 1.2e-13 50.9 0.0 2.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CDS25770.1 - 9.4e-13 47.8 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS25770.1 - 3e-12 45.9 0.0 7.3e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS25770.1 - 6.2e-09 35.4 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 CDS25770.1 - 0.00058 19.8 0.5 0.0027 17.7 0.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS25770.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS25770.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS25770.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CDS25770.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.32 CDS25771.1 - 8.2e-27 92.9 11.0 1.7e-06 28.6 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS25771.1 - 5.6e-14 52.2 4.8 0.00013 22.2 0.2 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS25771.1 - 4.4e-05 23.4 0.0 0.037 13.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDS25771.1 - 0.005 15.8 0.0 0.55 9.1 0.0 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CDS25771.1 - 0.013 14.8 0.1 0.74 9.1 0.0 2.7 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal EAF PF09816.9 CDS25772.1 - 1.5e-20 73.5 0.0 4.8e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor WD40 PF00400.32 CDS25773.1 - 6.3e-07 30.0 16.0 0.0048 17.7 0.9 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Dynein_IC2 PF11540.8 CDS25773.1 - 0.0013 18.6 0.1 0.0029 17.5 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ER_lumen_recept PF00810.18 CDS25774.1 - 5.7e-45 153.8 12.9 5.7e-45 153.8 12.9 2.5 2 1 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CDS25774.1 - 0.25 11.1 11.6 0.46 10.3 0.8 3.2 3 1 1 4 4 4 0 PQ loop repeat zf-H2C2_2 PF13465.6 CDS25775.1 - 3.7e-26 90.4 48.5 3.6e-08 33.5 3.0 7.1 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS25775.1 - 1.9e-21 75.2 61.3 0.001 19.4 6.7 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS25775.1 - 9.1e-14 51.0 57.3 0.0016 19.1 0.5 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS25775.1 - 7.3e-10 38.9 37.2 0.022 15.1 1.4 6.5 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS25775.1 - 0.00049 20.0 41.8 0.004 17.1 2.4 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 CDS25775.1 - 0.0064 16.8 4.1 0.0064 16.8 4.1 6.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDS25775.1 - 0.012 15.3 41.2 0.16 11.7 1.6 6.0 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-RING_7 PF02591.15 CDS25775.1 - 0.029 14.5 14.8 1.3 9.2 0.2 5.4 5 0 0 5 5 5 0 C4-type zinc ribbon domain zf-MYST PF17772.1 CDS25775.1 - 0.049 13.2 0.3 0.049 13.2 0.3 3.9 4 1 1 5 5 5 0 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 CDS25775.1 - 0.057 14.2 23.9 0.61 10.9 1.0 4.5 2 2 4 7 7 7 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 CDS25775.1 - 0.099 12.8 29.0 6.1 7.1 0.7 5.4 3 2 3 6 6 6 0 Zinc ribbon domain zf-C2HE PF16278.5 CDS25775.1 - 0.14 12.6 0.1 0.14 12.6 0.1 6.1 3 2 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 CDS25775.1 - 0.14 12.2 18.6 3.9 7.6 0.0 5.9 6 0 0 6 6 6 0 XPA protein N-terminal Sgf11 PF08209.11 CDS25775.1 - 0.16 11.6 0.2 0.16 11.6 0.2 5.1 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 CDS25775.1 - 0.16 11.6 0.1 0.16 11.6 0.1 6.4 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger DUF2256 PF10013.9 CDS25775.1 - 0.19 11.8 14.1 25 5.1 0.2 5.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.9 CDS25775.1 - 0.26 11.4 13.5 4.1 7.6 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger domain Ribosomal_L34e PF01199.18 CDS25775.1 - 0.26 11.6 5.0 0.38 11.1 0.2 2.9 2 1 0 2 2 2 0 Ribosomal protein L34e HypA PF01155.19 CDS25775.1 - 0.27 11.3 19.7 0.84 9.7 0.4 4.1 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 CDS25775.1 - 0.5 10.3 31.3 0.13 12.2 4.8 4.4 3 1 1 4 4 4 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CDS25775.1 - 0.93 9.5 30.1 0.62 10.1 1.7 4.9 3 1 3 6 6 6 0 Transposase zinc-ribbon domain FYDLN_acid PF09538.10 CDS25775.1 - 1.8 9.3 19.8 2.8 8.7 0.3 5.2 3 1 2 5 5 5 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 CDS25775.1 - 2.8 8.3 39.0 1.5 9.2 1.3 5.7 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Trm112p PF03966.16 CDS25775.1 - 3.9 8.1 5.3 11 6.7 0.9 3.4 3 2 0 3 3 2 0 Trm112p-like protein DUF2180 PF09947.9 CDS25775.1 - 3.9 7.5 8.6 11 6.1 0.5 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) zf-AN1 PF01428.16 CDS25775.1 - 6.2 7.1 43.6 9 6.5 0.9 6.7 5 2 1 6 6 6 0 AN1-like Zinc finger TFIIS_C PF01096.18 CDS25775.1 - 7.3 6.5 23.6 1.2 9.1 2.7 5.4 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) ABC1 PF03109.16 CDS25776.2 - 2.2e-34 118.2 0.0 4.1e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Tmemb_55A PF09788.9 CDS25777.1 - 1.9e-56 190.9 21.7 1.5e-35 122.5 9.5 2.1 2 0 0 2 2 2 2 Transmembrane protein 55A Tweety PF04906.13 CDS25777.1 - 0.011 14.5 2.1 0.015 14.0 2.1 1.1 1 0 0 1 1 1 0 Tweety HypA PF01155.19 CDS25777.1 - 0.012 15.6 7.5 0.11 12.5 1.3 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AlphaC_C PF17480.2 CDS25777.1 - 0.081 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 AlphaC C-terminal DUF3810 PF12725.7 CDS25777.1 - 0.6 9.4 2.4 0.83 8.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Phage_holin_3_6 PF07332.11 CDS25777.1 - 1 9.4 6.5 0.29 11.2 3.4 1.6 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf_UBZ PF18439.1 CDS25777.1 - 1.9 8.2 10.0 8.8 6.0 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CDS25777.1 - 4.6 7.2 19.8 2.5 8.1 0.1 4.7 4 1 1 5 5 5 0 zinc-ribbon domain SSB PF00436.25 CDS25778.1 - 0.0069 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti_2 PF13742.6 CDS25778.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PKI PF02827.16 CDS25778.1 - 0.39 11.0 0.1 0.39 11.0 0.1 1.7 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor adh_short PF00106.25 CDS25779.1 - 4.5e-36 124.1 0.0 5.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDS25779.1 - 1e-21 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS25779.1 - 1.4e-05 25.1 0.0 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 CDS25779.1 - 0.0091 16.3 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CDS25779.1 - 0.051 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 CDS25779.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_ab_N PF02874.23 CDS25779.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain F420_oxidored PF03807.17 CDS25779.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 CDS25779.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CDS25779.1 - 0.14 11.4 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PNISR PF15996.5 CDS25780.1 - 2.5e-19 70.4 0.1 2.5e-19 70.4 0.1 3.1 1 1 3 4 4 4 1 Arginine/serine-rich protein PNISR Bestrophin PF01062.21 CDS25781.1 - 4.8e-58 196.9 0.6 7.8e-58 196.2 0.6 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PAP2 PF01569.21 CDS25782.1 - 1.4e-21 76.7 2.9 2.6e-21 75.8 2.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CDS25782.1 - 0.0013 18.5 1.4 0.0031 17.2 1.4 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 CDS25782.1 - 0.012 16.1 1.7 0.012 16.1 1.7 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal FUSC_2 PF13515.6 CDS25782.1 - 0.17 12.0 5.5 0.083 13.0 1.1 2.5 2 1 1 3 3 3 0 Fusaric acid resistance protein-like HMG_CoA_synt_C PF08540.10 CDS25783.1 - 1.8e-74 250.9 1.5 7.5e-74 248.8 1.5 1.8 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CDS25783.1 - 1.4e-69 233.4 0.2 4.1e-69 231.9 0.0 1.8 3 0 0 3 3 3 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 CDS25783.1 - 0.012 15.7 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 CDS25783.1 - 0.015 15.1 0.2 0.031 14.1 0.2 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Kelch_1 PF01344.25 CDS25784.2 - 1.2e-22 79.2 0.5 1.7e-10 40.3 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CDS25784.2 - 1.6e-13 50.4 2.3 1.5e-06 28.3 0.0 4.8 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CDS25784.2 - 5.6e-13 48.6 0.7 5e-05 23.2 0.1 4.0 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 CDS25784.2 - 7.4e-13 48.7 0.0 1.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDS25784.2 - 3.8e-09 36.4 0.2 0.0025 17.8 0.0 3.8 4 0 0 4 4 4 3 Galactose oxidase, central domain BACK PF07707.15 CDS25784.2 - 2.2e-06 27.7 1.1 0.00017 21.7 0.1 2.9 2 1 1 3 3 3 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 CDS25784.2 - 1.2e-05 25.5 0.0 0.012 15.9 0.0 3.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS25784.2 - 0.0057 16.6 0.1 4.6 7.4 0.0 4.0 4 0 0 4 4 4 1 Kelch motif BACK PF07707.15 CDS25785.2 - 1.3e-06 28.4 0.1 3.4e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDS25785.2 - 0.0012 18.8 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.25 CDS25785.2 - 0.014 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 CDS25785.2 - 0.017 15.4 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Kelch motif WD40 PF00400.32 CDS25787.1 - 7.7e-09 36.0 3.0 0.027 15.3 0.0 5.6 5 2 0 5 5 5 2 WD domain, G-beta repeat Dynein_IC2 PF11540.8 CDS25787.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 CDS25787.1 - 0.072 13.4 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 CDS25788.1 - 2.1e-25 89.3 0.1 4.8e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain vATP-synt_E PF01991.18 CDS25788.1 - 0.0078 15.6 1.3 0.0078 15.6 1.3 2.1 2 1 0 2 2 2 1 ATP synthase (E/31 kDa) subunit CDC27 PF09507.10 CDS25788.1 - 3.6 6.9 33.7 6 6.1 33.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ASC PF00858.24 CDS25789.1 - 5.5e-57 193.7 5.1 6.6e-57 193.4 5.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel MMR_HSR1_Xtn PF16897.5 CDS25790.1 - 1.3e-42 144.1 1.7 2.3e-42 143.3 1.7 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CDS25790.1 - 6.8e-22 77.7 0.0 1.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CDS25790.1 - 4.1e-20 71.6 0.1 7.1e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CDS25790.1 - 2.1e-12 46.9 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS25790.1 - 2.4e-05 24.4 0.2 0.18 11.9 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CDS25790.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 CDS25790.1 - 0.014 15.3 0.6 0.054 13.4 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 CDS25790.1 - 0.015 15.5 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CDS25790.1 - 0.017 14.5 0.2 0.15 11.5 0.0 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDS25790.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SH3_2 PF07653.17 CDS25791.1 - 1.2e-09 37.7 0.0 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS25791.1 - 4.7e-09 35.7 0.0 7.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS25791.1 - 8.1e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2884 PF11101.8 CDS25791.1 - 0.39 10.2 1.6 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Hom_end PF05204.14 CDS25793.1 - 0.076 13.2 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease Histone PF00125.24 CDS25794.1 - 7.4e-54 181.6 1.5 8.3e-54 181.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS25794.1 - 7.4e-05 22.8 0.2 0.00016 21.8 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDS25794.1 - 8.5e-05 23.2 1.6 0.0001 22.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CDS25794.1 - 0.00046 20.5 0.0 0.0007 19.9 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDS25794.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase_Tyr PF07714.17 CDS25795.1 - 4.2e-43 147.5 0.0 5.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25795.1 - 2.5e-23 82.8 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS25795.1 - 2.1e-05 24.5 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RIO1 PF01163.22 CDS25795.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 CDS25796.1 - 4.4e-68 229.4 0.0 6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS25796.1 - 3.3e-37 128.3 0.0 4.4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 CDS25796.1 - 2e-08 33.7 0.1 7.3e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH2 PF00017.24 CDS25796.1 - 4e-08 33.2 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CDS25796.1 - 3.3e-07 30.1 0.0 9.5e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 CDS25796.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SH3_2 PF07653.17 CDS25796.1 - 0.037 13.7 0.0 0.15 11.7 0.0 2.1 2 1 0 2 2 2 0 Variant SH3 domain APH PF01636.23 CDS25796.1 - 0.046 13.6 0.1 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CDS25796.1 - 0.064 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CDS25796.1 - 0.071 12.0 0.1 1.1 8.2 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Toxin_37 PF11415.8 CDS25797.1 - 0.083 12.7 1.6 0.16 11.9 1.6 1.4 1 0 0 1 1 1 0 Antifungal peptide termicin UCH PF00443.29 CDS25798.1 - 1.6e-40 139.2 0.1 3.1e-40 138.3 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS25798.1 - 1.8e-06 27.8 2.8 0.021 14.4 0.5 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDS25798.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family EF-hand_1 PF00036.32 CDS25799.1 - 5.7e-15 53.7 2.2 1.2e-07 30.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS25799.1 - 1.3e-13 51.2 0.2 2.2e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS25799.1 - 1.9e-10 39.8 1.8 4.6e-05 23.0 0.5 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS25799.1 - 1.8e-09 37.3 1.5 1.7e-07 31.0 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS25799.1 - 3.4e-09 35.8 0.6 3.8e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CDS25799.1 - 0.004 17.4 0.1 0.0073 16.6 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain Dockerin_1 PF00404.18 CDS25799.1 - 0.051 13.8 0.7 0.22 11.7 0.7 1.9 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_4 PF12763.7 CDS25799.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HLH PF00010.26 CDS25803.1 - 2.5e-14 53.0 4.2 4.6e-14 52.1 4.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.8 CDS25803.1 - 1.6e-11 45.5 0.8 1.6e-11 45.5 0.8 2.3 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor TFIIA PF03153.13 CDS25803.1 - 0.013 15.5 7.1 0.017 15.1 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CDS25804.1 - 1.1e-14 54.1 51.7 9.9e-05 22.6 3.5 6.0 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS25804.1 - 2.6e-09 37.1 45.4 0.0066 17.2 0.7 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS25804.1 - 1.8e-05 24.9 59.4 0.00019 21.7 1.1 6.8 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDS25804.1 - 0.7 10.2 22.9 4.2 7.8 0.5 5.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS25804.1 - 1.7 8.4 11.8 4.4 7.1 1.0 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Fer4_7 PF12838.7 CDS25804.1 - 3.2 8.4 11.9 3.5e+02 1.9 11.9 3.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Adap_comp_sub PF00928.21 CDS25805.1 - 5.1e-21 75.2 0.0 7.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDS25805.1 - 0.0033 17.4 0.1 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4990 PF16380.5 CDS25805.1 - 0.057 13.5 0.0 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function zf-met PF12874.7 CDS25806.2 - 8.6e-16 57.8 27.1 6.9e-07 29.4 4.8 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS25806.2 - 1.1e-09 38.3 23.4 0.00055 20.1 3.3 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS25806.2 - 0.00036 20.8 21.2 0.053 13.9 1.5 3.6 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) DZF PF07528.14 CDS25806.2 - 0.00061 19.5 0.1 0.013 15.1 0.0 2.5 2 0 0 2 2 2 1 DZF domain zf-U1 PF06220.12 CDS25806.2 - 0.019 14.7 16.7 0.41 10.5 0.7 3.5 3 0 0 3 3 3 0 U1 zinc finger Skp1_POZ PF03931.15 CDS25807.1 - 0.052 13.7 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain MIP PF00230.20 CDS25808.1 - 1.1e-22 80.9 8.5 1.3e-22 80.6 8.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.13 CDS25808.1 - 0.055 13.7 13.6 0.098 12.9 0.3 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein DHHC PF01529.20 CDS25809.1 - 4.7e-29 101.2 10.6 6.7e-29 100.7 10.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase WH2 PF02205.20 CDS25810.1 - 3.7e-05 23.4 0.0 8.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 CDS25810.1 - 0.014 14.9 3.2 0.014 14.9 3.2 3.1 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.31 CDS25811.1 - 3.8e-11 42.9 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 CDS25811.1 - 2.3e-08 33.7 0.6 7.9e-08 32.0 0.2 2.1 2 0 0 2 2 2 1 GYF domain 2 GYF PF02213.16 CDS25811.1 - 0.15 11.7 1.6 0.33 10.7 1.6 1.5 1 0 0 1 1 1 0 GYF domain DIM1 PF02966.16 CDS25812.1 - 9.5e-68 226.1 0.3 1.1e-67 225.9 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDS25812.1 - 7.2e-05 22.7 0.1 9e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDS25812.1 - 0.007 16.5 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CDS25812.1 - 0.0088 16.0 0.3 0.016 15.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.6 CDS25812.1 - 0.015 15.7 0.4 0.022 15.1 0.4 1.3 1 1 0 1 1 1 0 Thioredoxin-like OATP PF03137.20 CDS25813.1 - 2.7e-117 392.3 0.4 1.5e-116 389.9 0.1 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CDS25813.1 - 5.6e-14 51.8 20.8 5.4e-11 42.0 11.7 3.2 3 1 0 3 3 3 2 Major Facilitator Superfamily dNK PF01712.19 CDS25814.1 - 7.3e-21 75.0 2.1 2e-20 73.5 2.1 1.7 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_17 PF13207.6 CDS25814.1 - 0.01 16.3 0.1 1.1 9.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDS25814.1 - 0.061 13.9 0.0 0.36 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDS25814.1 - 0.076 13.2 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CDS25814.1 - 0.086 12.8 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gaa1 PF04114.14 CDS25815.1 - 5.4e-104 349.0 0.2 6.4e-104 348.7 0.2 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component fn3_4 PF16794.5 CDS25816.1 - 4.7e-12 45.7 0.0 6.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-III type domain Vps54_N PF10475.9 CDS25816.1 - 0.015 14.6 1.4 0.02 14.2 1.4 1.1 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Herpes_UL6 PF01763.16 CDS25816.1 - 0.016 13.8 0.6 0.02 13.5 0.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like COG2 PF06148.11 CDS25816.1 - 0.031 14.3 2.0 0.047 13.8 2.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LXG PF04740.12 CDS25816.1 - 0.038 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Pox_A_type_inc PF04508.12 CDS25816.1 - 0.041 13.7 0.5 0.096 12.6 0.5 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat GldM_N PF12081.8 CDS25816.1 - 0.06 13.4 0.4 0.082 13.0 0.4 1.1 1 0 0 1 1 1 0 GldM N-terminal domain UPRTase PF14681.6 CDS25817.1 - 3.9e-47 160.4 0.0 5.4e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CDS25817.1 - 5.2e-05 22.8 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ORF6C PF10552.9 CDS25817.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain MWFE PF15879.5 CDS25818.1 - 0.85 9.8 3.6 1.5 9.1 3.6 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit TPPII PF12580.8 CDS25819.1 - 8.7e-10 38.4 1.0 2.5e-09 36.9 1.0 1.7 1 1 0 1 1 1 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.22 CDS25820.1 - 5.1e-53 180.3 0.1 7.9e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family PNK3P PF08645.11 CDS25821.1 - 2e-50 170.6 0.0 5.7e-50 169.2 0.0 1.7 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDS25821.1 - 6.2e-16 58.9 0.0 2.1e-13 50.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDS25821.1 - 0.00026 20.6 0.2 0.012 15.0 0.2 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CDS25821.1 - 0.0019 17.5 0.0 0.0079 15.5 0.0 1.8 1 1 1 2 2 2 1 Zeta toxin 6PF2K PF01591.18 CDS25821.1 - 0.0044 16.4 0.1 0.018 14.4 0.0 1.9 1 1 1 2 2 2 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 CDS25821.1 - 0.039 14.4 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PGP_phosphatase PF09419.10 CDS25821.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase CPL PF08144.11 CDS25823.1 - 2.5e-12 47.3 1.1 6e-09 36.4 0.0 4.1 4 0 0 4 4 4 2 CPL (NUC119) domain SBP_bac_11 PF13531.6 CDS25823.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Forkhead PF00250.18 CDS25824.1 - 1e-33 115.4 0.0 1.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain SH2 PF00017.24 CDS25826.1 - 2.7e-08 33.8 0.0 7.9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 SH2 domain Pkinase PF00069.25 CDS25827.1 - 3.4e-38 131.5 0.0 4.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25827.1 - 4.4e-18 65.5 0.0 5.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS25827.1 - 0.00038 20.5 0.1 0.0035 17.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS25827.1 - 0.0018 17.3 0.2 0.0031 16.5 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS25827.1 - 0.018 14.4 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS25827.1 - 0.038 13.3 0.0 0.42 9.9 0.0 2.3 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CDS25827.1 - 0.061 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Trypsin PF00089.26 CDS25828.1 - 1.9e-40 139.0 0.0 2.5e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDS25828.1 - 0.0014 19.6 0.0 0.0024 18.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CDS25828.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 CDS25829.1 - 1.8e-23 83.5 0.0 2.7e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDS25829.1 - 0.062 13.7 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) efb-c PF12199.8 CDS25829.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Trypsin PF00089.26 CDS25830.1 - 7.3e-32 111.0 0.0 1.1e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDS25830.1 - 0.0068 16.8 0.3 0.04 14.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1986) DUF316 PF03761.15 CDS25830.1 - 0.092 12.3 0.8 0.18 11.3 0.4 1.6 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 RabGAP-TBC PF00566.18 CDS25831.1 - 4.2e-60 203.1 2.4 4.2e-60 203.1 2.4 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Tetraspanin PF00335.20 CDS25833.2 - 6.3e-16 58.8 17.0 7.7e-16 58.5 17.0 1.0 1 0 0 1 1 1 1 Tetraspanin family rve_3 PF13683.6 CDS25833.2 - 0.052 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Skp1_POZ PF03931.15 CDS25836.1 - 3.3e-06 27.2 0.2 5.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain SAPS PF04499.15 CDS25837.2 - 2.7e-36 125.4 1.7 1.2e-20 73.8 3.9 3.1 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Lig_chan PF00060.26 CDS25839.1 - 1.4e-40 138.5 0.2 3e-40 137.5 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDS25839.1 - 2e-29 102.1 0.0 8.4e-29 100.1 0.0 2.0 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 CDS25839.1 - 1.7e-20 73.5 0.1 2.5e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 CDS25839.1 - 1.2e-16 60.9 0.0 5e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 AbiJ_NTD5 PF18865.1 CDS25839.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 zf-Di19 PF05605.12 CDS25840.1 - 0.00012 22.3 31.2 0.057 13.7 4.3 6.4 5 2 1 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDS25840.1 - 0.001 19.4 33.5 2.5 8.7 0.5 9.2 9 0 0 9 9 9 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS25840.1 - 0.003 17.8 1.6 22 5.5 0.0 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_12 PF18658.1 CDS25840.1 - 0.011 15.2 7.6 1.1 8.9 0.2 4.7 4 1 1 5 5 5 0 Zinc-finger C2H2-type zf-MYST PF17772.1 CDS25840.1 - 0.025 14.2 0.2 0.37 10.4 0.1 2.8 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2 PF00096.26 CDS25840.1 - 0.081 13.4 37.5 2.9 8.5 0.0 9.6 11 0 0 11 11 11 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CDS25840.1 - 0.11 12.3 0.1 0.11 12.3 0.1 6.1 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-BED PF02892.15 CDS25840.1 - 0.87 9.7 17.0 0.94 9.6 0.3 6.5 7 1 0 7 7 7 0 BED zinc finger DUF5320 PF17253.2 CDS25840.1 - 1.2 10.3 8.2 3.8 8.7 3.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) zf-C2H2_6 PF13912.6 CDS25840.1 - 2.4 8.3 11.9 24 5.1 0.0 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS25840.1 - 4.3 7.7 11.1 15 6.0 0.1 4.5 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) PQ-loop PF04193.14 CDS25843.1 - 9.6e-33 111.8 20.1 1.1e-17 63.5 4.6 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4044 PF13253.6 CDS25843.1 - 6.1 6.5 7.0 0.37 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Ig_3 PF13927.6 CDS25846.1 - 0.0066 17.0 0.3 0.028 15.0 0.0 2.2 3 0 0 3 3 3 1 Immunoglobulin domain DUF4200 PF13863.6 CDS25847.1 - 2.6e-17 63.3 10.9 2.6e-17 63.3 10.9 4.5 3 2 1 4 4 4 2 Domain of unknown function (DUF4200) Urm1 PF09138.11 CDS25847.1 - 0.1 13.0 0.7 0.45 10.9 0.7 2.1 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) TBPIP PF07106.13 CDS25847.1 - 0.26 11.3 2.7 0.92 9.5 2.7 1.9 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain POR PF01558.18 CDS25848.2 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase CTP_transf_like PF01467.26 CDS25849.2 - 2.5e-15 56.9 0.0 1.8e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like Tom22 PF04281.13 CDS25850.1 - 1.9e-14 53.6 0.5 2.3e-14 53.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HORMA PF02301.18 CDS25851.1 - 3e-47 160.9 0.0 6.5e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 CDS25851.1 - 2e-07 30.8 9.8 4.2e-07 29.8 9.8 1.6 1 0 0 1 1 1 1 PHD-finger Rrf2 PF02082.20 CDS25851.1 - 0.015 15.6 0.0 0.047 14.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator PHD_3 PF13922.6 CDS25851.1 - 0.57 10.6 6.9 1.8 9.0 6.9 1.9 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Consortin_C PF15281.6 CDS25852.1 - 0.098 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Consortin C-terminus RhoGAP PF00620.27 CDS25853.1 - 1.8e-28 99.3 0.0 8.1e-28 97.2 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Topoisom_bac PF01131.20 CDS25854.1 - 3.9e-111 372.0 0.0 4.8e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CDS25854.1 - 1.9e-29 101.5 13.2 3.6e-15 55.8 0.5 4.0 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 CDS25854.1 - 2e-16 60.1 0.0 5.6e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 CDS25854.1 - 9.3e-06 25.3 5.3 0.0013 18.5 0.1 2.9 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-C2H2_10 PF16588.5 CDS25854.1 - 0.0038 16.9 1.0 0.0038 16.9 1.0 2.1 2 0 0 2 2 2 1 C2H2 zinc-finger WW PF00397.26 CDS25855.2 - 3.8e-10 39.7 0.3 3.8e-10 39.7 0.3 2.2 2 0 0 2 2 2 1 WW domain VWA_N PF08399.11 CDS25857.2 - 0.021 15.3 0.5 0.037 14.5 0.5 1.4 1 0 0 1 1 1 0 VWA N-terminal RT_RNaseH_2 PF17919.1 CDS25860.2 - 3.3e-06 27.1 0.1 6.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HECT PF00632.25 CDS25861.2 - 6.3e-06 25.9 0.0 8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SRP54 PF00448.22 CDS25863.1 - 7.4e-76 254.2 0.1 1.3e-75 253.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDS25863.1 - 3.5e-27 94.9 3.1 1.9e-25 89.3 0.1 2.9 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDS25863.1 - 1.8e-18 66.5 2.3 1.8e-18 66.5 2.3 2.4 3 0 0 3 3 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CDS25863.1 - 2.1e-06 27.4 1.6 3.9e-05 23.3 1.6 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDS25863.1 - 7.3e-06 26.2 0.0 2.2e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDS25863.1 - 1.2e-05 25.7 0.1 5e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDS25863.1 - 4.4e-05 23.9 0.0 0.00017 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 CDS25863.1 - 0.00012 21.5 0.8 0.14 11.6 0.9 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 CDS25863.1 - 0.00013 21.8 0.1 0.00036 20.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDS25863.1 - 0.00027 21.0 0.0 0.00075 19.6 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 CDS25863.1 - 0.00028 20.8 0.1 0.0007 19.5 0.1 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 CDS25863.1 - 0.0003 21.1 0.6 0.0038 17.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain DUF2209 PF09974.9 CDS25863.1 - 0.00032 21.0 0.4 0.0008 19.7 0.4 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) AAA PF00004.29 CDS25863.1 - 0.00041 20.8 2.2 0.067 13.6 0.1 3.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CDS25863.1 - 0.00089 19.3 0.4 0.0028 17.7 0.4 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 CDS25863.1 - 0.0011 19.1 0.1 0.0076 16.3 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CDS25863.1 - 0.0026 17.1 0.1 0.0059 15.9 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 CDS25863.1 - 0.0055 15.7 0.1 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDS25863.1 - 0.0062 17.1 0.0 0.02 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 CDS25863.1 - 0.0078 16.1 0.5 0.022 14.7 0.1 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 CDS25863.1 - 0.0084 15.7 1.3 0.018 14.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain 6PF2K PF01591.18 CDS25863.1 - 0.0086 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_28 PF13521.6 CDS25863.1 - 0.0092 16.2 0.3 0.029 14.6 0.2 1.8 1 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CDS25863.1 - 0.0094 16.3 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CDS25863.1 - 0.011 15.5 0.1 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 CDS25863.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDS25863.1 - 0.013 15.2 0.7 0.22 11.2 0.0 3.0 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_14 PF13173.6 CDS25863.1 - 0.035 14.1 0.5 0.23 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 CDS25863.1 - 0.044 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.6 CDS25863.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS25863.1 - 0.055 13.0 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mur_ligase_M PF08245.12 CDS25863.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Mur ligase middle domain VirE PF05272.11 CDS25863.1 - 0.065 13.0 0.2 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E Thymidylate_kin PF02223.17 CDS25863.1 - 0.068 12.8 0.4 0.19 11.4 0.1 1.9 2 0 0 2 2 1 0 Thymidylate kinase Cytidylate_kin PF02224.18 CDS25863.1 - 0.097 12.4 0.2 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 CDS25863.1 - 0.099 11.8 0.2 0.32 10.1 0.2 1.8 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 CDS25863.1 - 0.1 12.4 0.3 0.39 10.4 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CDS25863.1 - 0.11 12.8 0.4 1 9.8 0.1 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CDS25863.1 - 0.12 12.3 0.5 0.38 10.6 0.1 2.1 2 0 0 2 2 1 0 NTPase AAA_24 PF13479.6 CDS25863.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDS25863.1 - 0.13 11.3 0.7 0.58 9.3 0.1 2.2 2 1 1 3 3 3 0 G-protein alpha subunit AAA_8 PF12780.7 CDS25863.1 - 0.16 11.2 2.5 1.1 8.6 0.0 3.1 4 0 0 4 4 3 0 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 CDS25863.1 - 0.25 11.1 0.9 2.6 7.8 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rbc25 PF08292.12 CDS25864.1 - 2.6e-33 115.0 4.6 9.9e-33 113.1 4.6 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CDS25864.1 - 7e-15 55.2 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDS25864.1 - 0.078 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain TAP42 PF04177.12 CDS25865.1 - 4.5e-67 226.4 3.1 5.5e-67 226.2 3.1 1.1 1 0 0 1 1 1 1 TAP42-like family GoLoco PF02188.17 CDS25865.1 - 1.3 8.6 5.7 11 5.7 0.0 3.2 3 0 0 3 3 3 0 GoLoco motif DUF4604 PF15377.6 CDS25866.1 - 6.2e-13 49.5 16.5 8.2e-13 49.1 16.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) YflT PF11181.8 CDS25866.1 - 0.042 14.4 0.0 0.042 14.4 0.0 2.0 2 1 0 2 2 2 0 Heat induced stress protein YflT SHIPPO-rpt PF07004.12 CDS25867.1 - 9.8e-13 48.4 39.5 0.0049 17.7 2.1 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Carb_anhydrase PF00194.21 CDS25868.1 - 8.2e-67 225.4 0.0 9.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Utp21 PF04192.12 CDS25870.2 - 5.9e-45 153.6 10.3 6.6e-22 78.2 1.6 3.8 2 2 0 2 2 2 2 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CDS25870.2 - 0.0039 18.0 15.4 12 6.9 0.1 7.9 8 0 0 8 8 8 1 WD domain, G-beta repeat DUF1045 PF06299.12 CDS25870.2 - 0.012 15.6 3.0 2.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) TerB PF05099.13 CDS25870.2 - 0.019 14.9 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF520 PF04461.13 CDS25870.2 - 0.032 14.4 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF520) zf-LYAR PF08790.11 CDS25870.2 - 0.14 12.1 0.2 32 4.5 0.0 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Hira PF07569.11 CDS25870.2 - 0.16 11.7 0.0 0.95 9.1 0.0 2.2 3 0 0 3 3 3 0 TUP1-like enhancer of split COX14 PF14880.6 CDS25870.2 - 0.2 11.5 0.4 0.43 10.5 0.4 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RWD PF05773.22 CDS25871.1 - 0.00068 19.9 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Ank_2 PF12796.7 CDS25872.1 - 7.8e-37 125.7 2.6 4.1e-11 43.3 0.3 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25872.1 - 9.2e-34 115.4 0.6 2.1e-10 40.9 0.1 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS25872.1 - 3.4e-26 91.0 1.1 3.7e-07 30.3 0.1 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS25872.1 - 1.1e-23 80.8 3.0 0.039 14.5 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 CDS25872.1 - 4.9e-22 77.4 7.3 0.046 14.2 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat HTH_48 PF17906.1 CDS25873.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase PDEase_I PF00233.19 CDS25876.1 - 5.9e-73 245.5 1.9 1.1e-72 244.6 1.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDE4_UCR PF18100.1 CDS25876.1 - 1e-46 158.4 1.6 1e-46 158.4 1.6 2.3 2 0 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) DeoC PF01791.9 CDS25877.2 - 9.6e-20 71.2 0.0 1.3e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF4516 PF14990.6 CDS25877.2 - 0.0047 16.6 1.9 0.0063 16.2 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4516) NOT2_3_5 PF04153.18 CDS25878.1 - 1.6e-18 67.1 0.0 3.7e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RB_A PF01858.17 CDS25879.2 - 1.9e-44 151.9 0.4 1.1e-43 149.4 0.1 2.2 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 CDS25879.2 - 8.8e-42 142.3 0.0 4.1e-39 133.6 0.0 2.5 2 0 0 2 2 2 2 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 CDS25879.2 - 4.5e-32 110.5 0.1 4.2e-31 107.3 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) DUF4995 PF16386.5 CDS25879.2 - 0.026 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function ABC_membrane PF00664.23 CDS25881.2 - 8.1e-54 183.1 10.5 8.1e-54 183.1 10.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDS25881.2 - 6.6e-35 120.6 0.0 2e-34 119.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDS25881.2 - 5.2e-06 26.1 1.4 0.00034 20.1 0.1 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CDS25881.2 - 0.00028 19.8 0.5 0.00071 18.5 0.1 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDS25881.2 - 0.00039 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CDS25881.2 - 0.0012 18.8 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 CDS25881.2 - 0.0066 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 CDS25881.2 - 0.014 15.8 2.1 0.1 13.0 2.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 CDS25881.2 - 0.019 15.5 0.1 0.062 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDS25881.2 - 0.022 15.1 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDS25881.2 - 0.043 13.5 0.4 0.33 10.6 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDS25881.2 - 0.056 13.4 0.2 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 CDS25881.2 - 0.066 12.9 0.2 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CDS25881.2 - 0.067 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 CDS25881.2 - 0.078 13.2 0.9 0.68 10.2 0.9 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CDS25881.2 - 0.08 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 CDS25881.2 - 0.13 11.6 0.3 0.3 10.4 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CDS25882.2 - 1e-30 107.0 0.0 1.7e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDS25882.2 - 5.4e-08 32.8 0.7 7.5e-08 32.4 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CDS25882.2 - 1.4e-06 27.9 0.0 0.00076 19.0 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDS25882.2 - 6.8e-06 26.6 0.7 0.0015 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDS25882.2 - 9.2e-05 22.7 0.0 0.0022 18.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CDS25882.2 - 0.00058 19.7 0.0 0.00072 19.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 CDS25882.2 - 0.0013 17.6 0.0 0.0059 15.5 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 CDS25882.2 - 0.0015 18.4 0.1 0.018 14.9 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 CDS25882.2 - 0.0021 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SbcCD_C PF13558.6 CDS25882.2 - 0.0046 17.2 1.2 0.075 13.3 0.7 2.6 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CDS25882.2 - 0.011 15.3 0.1 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDS25882.2 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CDS25882.2 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CDS25882.2 - 0.019 14.2 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 CDS25882.2 - 0.027 14.9 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDS25882.2 - 0.032 14.0 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDS25882.2 - 0.037 14.0 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDS25882.2 - 0.059 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 CDS25882.2 - 0.09 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 CDS25882.2 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DHHC PF01529.20 CDS25883.1 - 8.3e-28 97.2 16.0 8.3e-28 97.2 16.0 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase Forkhead PF00250.18 CDS25884.1 - 1.6e-38 130.8 0.1 3.8e-38 129.6 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CDS25884.1 - 3.6e-06 27.2 0.0 1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDS25884.1 - 0.031 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Filament PF00038.21 CDS25885.1 - 0.048 13.2 59.8 0.39 10.2 4.2 4.0 2 1 2 4 4 4 0 Intermediate filament protein FPP PF05911.11 CDS25885.1 - 0.42 8.7 62.4 0.0088 14.3 4.3 4.0 2 1 1 4 4 4 0 Filament-like plant protein, long coiled-coil YabA PF06156.13 CDS25885.1 - 5.8 7.6 58.0 0.098 13.3 5.5 7.0 3 3 3 6 6 6 0 Initiation control protein YabA WXG100 PF06013.12 CDS25885.1 - 9.6 6.5 7.4 9.4 6.5 0.1 4.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG zf-RING_2 PF13639.6 CDS25886.1 - 2.9e-11 43.5 6.0 2.9e-11 43.5 6.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDS25886.1 - 3.2e-08 33.2 3.4 3.2e-08 33.2 3.4 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CDS25886.1 - 2e-06 28.0 7.1 8.2e-06 26.0 7.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDS25886.1 - 9.7e-06 25.3 6.5 2.6e-05 24.0 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS25886.1 - 4.8e-05 23.3 2.6 4.8e-05 23.3 2.6 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS25886.1 - 0.00036 20.3 4.6 0.00036 20.3 4.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS25886.1 - 0.00075 19.4 2.6 0.00075 19.4 2.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDS25886.1 - 0.0014 18.6 2.2 0.0031 17.5 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDS25886.1 - 0.0024 17.5 3.6 0.0049 16.5 3.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDS25886.1 - 0.0063 16.4 2.0 0.017 15.0 2.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDS25886.1 - 0.014 15.6 7.5 0.028 14.6 4.3 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 CDS25886.1 - 0.029 14.5 3.6 0.067 13.3 3.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 CDS25886.1 - 0.088 12.7 4.6 0.21 11.5 4.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-AN1 PF01428.16 CDS25886.1 - 0.94 9.7 5.7 0.32 11.2 1.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger TCR PF03638.15 CDS25887.2 - 4.1e-21 75.0 47.5 1.3e-10 41.4 20.8 2.5 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF16 PF01519.16 CDS25887.2 - 5.4e-05 23.6 2.1 0.29 11.6 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function DUF16 SlyX PF04102.12 CDS25887.2 - 0.00043 20.8 11.8 0.063 13.9 0.8 4.3 4 0 0 4 4 4 2 SlyX DUF4763 PF15960.5 CDS25887.2 - 0.00081 18.8 2.7 0.54 9.5 0.5 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4763) DUF5082 PF16888.5 CDS25887.2 - 0.0052 17.1 0.5 3.3 8.0 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) GIT_CC PF16559.5 CDS25887.2 - 0.0072 16.2 3.5 1.3 8.9 0.2 3.0 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 CDS25887.2 - 0.0091 16.3 2.7 1.3 9.4 0.3 3.2 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2403 PF10290.9 CDS25887.2 - 0.014 15.8 10.6 1.6 9.2 0.1 4.3 4 0 0 4 4 4 0 Glycine-rich protein domain (DUF2403) DUF3450 PF11932.8 CDS25887.2 - 0.016 14.5 2.3 0.59 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMA7 PF09072.10 CDS25887.2 - 0.024 15.4 0.2 19 6.2 0.0 2.8 2 0 0 2 2 2 0 Translation machinery associated TMA7 Vps23_core PF09454.10 CDS25887.2 - 0.025 14.5 1.2 9.8 6.2 0.1 2.7 2 0 0 2 2 2 0 Vps23 core domain MerR-DNA-bind PF09278.11 CDS25887.2 - 0.073 13.6 2.1 12 6.5 0.1 3.1 2 1 0 2 2 2 0 MerR, DNA binding HalX PF08663.10 CDS25887.2 - 0.097 13.0 0.7 14 6.1 0.0 2.7 2 0 0 2 2 2 0 HalX domain SKA1 PF07160.12 CDS25887.2 - 0.16 11.8 0.1 0.16 11.8 0.1 4.2 4 1 0 5 5 4 0 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 CDS25887.2 - 0.2 12.2 4.8 7 7.2 0.9 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BacteriocIIc_cy PF12173.8 CDS25887.2 - 0.73 10.1 7.6 8.7 6.7 0.9 2.4 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like DEDD_Tnp_IS110 PF01548.17 CDS25887.2 - 0.85 9.5 4.1 5.9 6.7 0.3 2.5 2 0 0 2 2 2 0 Transposase bZIP_2 PF07716.15 CDS25887.2 - 0.88 9.7 2.4 48 4.1 0.0 3.4 3 0 0 3 3 3 0 Basic region leucine zipper IPP-2 PF04979.14 CDS25888.2 - 0.0083 16.9 4.2 0.0083 16.9 4.2 2.1 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Aconitase PF00330.20 CDS25892.1 - 2.5e-147 491.6 0.0 3.4e-147 491.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDS25892.1 - 4.1e-44 150.1 0.0 8.1e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNase_II_C_S1 PF18614.1 CDS25892.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Bromodomain PF00439.25 CDS25893.1 - 2.1e-13 50.1 0.1 7.5e-13 48.4 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Phage_holin_7_1 PF16081.5 CDS25893.1 - 0.076 13.2 1.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family RFX_DNA_binding PF02257.15 CDS25894.1 - 1.4e-33 115.3 0.0 3.7e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 CDS25894.1 - 0.033 14.7 0.1 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus D5 protein-like FYVE PF01363.21 CDS25895.1 - 0.022 14.9 10.3 0.2 11.8 10.3 2.3 1 1 0 1 1 1 0 FYVE zinc finger Tektin PF03148.14 CDS25896.1 - 1.8e-68 231.1 25.3 2e-68 230.9 25.3 1.0 1 0 0 1 1 1 1 Tektin family Cas6 PF09559.10 CDS25896.1 - 0.15 12.0 2.8 0.17 11.9 0.7 2.0 2 0 0 2 2 2 0 Cas6 Crispr DUF5082 PF16888.5 CDS25896.1 - 0.16 12.2 21.7 0.39 11.0 5.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) HrpB7 PF09486.10 CDS25896.1 - 0.98 9.8 9.4 0.93 9.9 1.0 3.1 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 CDS25896.1 - 2.1 8.4 10.6 7.5 6.6 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Sulfatase_C PF14707.6 CDS25896.1 - 2.6 8.8 4.4 0.68 10.7 0.4 2.1 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase Prefoldin_2 PF01920.20 CDS25896.1 - 7.8 6.5 19.9 7.6 6.5 5.6 3.6 3 0 0 3 3 3 0 Prefoldin subunit Pkinase PF00069.25 CDS25897.2 - 2.7e-66 223.7 0.0 2.3e-65 220.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CDS25897.2 - 1.9e-33 114.4 0.1 1.1e-17 63.8 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CDS25897.2 - 4.8e-32 111.3 0.0 3.7e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS25897.2 - 0.00058 18.8 0.1 0.0016 17.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDS25897.2 - 0.0097 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS25897.2 - 0.02 14.8 0.0 0.084 12.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Trimer_CC PF08954.11 CDS25897.2 - 0.027 14.0 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 Trimerisation motif Gemin7 PF11095.8 CDS25897.2 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Pkinase PF00069.25 CDS25898.1 - 1.1e-27 97.1 0.0 4.4e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25898.1 - 4.1e-22 78.7 0.0 3.3e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 CDS25898.1 - 1.4e-16 60.0 26.9 7.9e-05 22.3 0.6 7.7 6 2 0 6 6 6 5 Leucine rich repeat COR PF16095.5 CDS25898.1 - 9.1e-12 45.2 0.0 3.3e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain LRR_4 PF12799.7 CDS25898.1 - 1.1e-11 44.8 37.4 0.00093 19.5 1.7 9.4 7 2 2 9 9 9 4 Leucine Rich repeats (2 copies) Roc PF08477.13 CDS25898.1 - 6.8e-08 32.8 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 CDS25898.1 - 1.4e-05 25.6 2.9 0.0004 20.9 0.1 3.7 4 1 0 4 4 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25898.1 - 1.6e-05 25.4 7.1 0.0019 18.8 0.2 4.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) LRR_6 PF13516.6 CDS25898.1 - 7.5e-05 22.5 18.3 0.093 12.8 0.0 8.4 8 0 0 8 8 8 1 Leucine Rich repeat Ank_5 PF13857.6 CDS25898.1 - 0.0012 19.1 0.8 1.7 9.0 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 CDS25898.1 - 0.046 13.8 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_1 PF00560.33 CDS25898.1 - 0.057 14.0 32.3 19 6.3 0.0 10.6 9 1 0 9 9 8 0 Leucine Rich Repeat Reg_prop PF07494.11 CDS25898.1 - 0.16 12.3 0.1 2.1 8.9 0.1 3.1 1 0 0 1 1 1 0 Two component regulator propeller LRR_9 PF14580.6 CDS25898.1 - 1.2 8.7 4.0 5 6.6 0.5 2.9 3 0 0 3 3 3 0 Leucine-rich repeat Ank_3 PF13606.6 CDS25898.1 - 1.9 9.3 10.6 44 5.1 0.2 5.9 6 0 0 6 6 5 0 Ankyrin repeat Telomere_reg-2 PF10193.9 CDS25899.2 - 0.15 12.5 0.2 2.9 8.4 0.1 3.4 3 0 0 3 3 3 0 Telomere length regulation protein Smg8_Smg9 PF10220.9 CDS25900.1 - 1.7e-69 235.2 41.8 1.5e-38 132.8 11.8 6.1 4 2 0 4 4 4 3 Smg8_Smg9 Pkinase PF00069.25 CDS25901.1 - 2.6e-65 220.4 0.0 4.9e-65 219.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25901.1 - 3.3e-46 157.7 0.0 9.3e-46 156.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 CDS25901.1 - 4e-07 29.7 0.3 1e-06 28.3 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 CDS25901.1 - 0.00026 20.4 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS25901.1 - 0.0056 16.3 0.9 0.01 15.5 0.3 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 CDS25902.1 - 7e-70 235.4 0.0 9e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25902.1 - 7.6e-37 127.0 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDS25902.1 - 3.5e-07 30.8 0.9 1.3e-06 29.0 0.9 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDS25902.1 - 9.1e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS25902.1 - 0.0047 16.3 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDS25902.1 - 0.07 12.7 0.1 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDS25902.1 - 0.083 11.8 0.1 0.16 10.9 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Chromosome_seg PF13889.6 CDS25903.1 - 1e-18 67.2 1.6 2.4e-18 66.1 1.6 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 CDS25903.1 - 1.7e-11 44.5 0.0 5.3e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) zf-HC5HC2H_2 PF13832.6 CDS25904.1 - 1.7e-25 89.3 19.1 4.7e-24 84.7 3.1 3.5 3 0 0 3 3 3 2 PHD-zinc-finger like domain PHD PF00628.29 CDS25904.1 - 3.6e-19 68.4 33.1 8.6e-11 41.6 5.8 4.3 4 0 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.6 CDS25904.1 - 4.1e-15 55.8 21.9 2.4e-13 50.1 2.4 3.8 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CDS25904.1 - 0.0026 17.3 24.5 0.12 11.9 0.8 4.6 3 1 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 CDS25904.1 - 0.004 16.8 0.6 0.004 16.8 0.6 3.5 3 1 0 3 3 3 2 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CDS25904.1 - 0.012 15.5 23.2 0.16 11.9 1.4 3.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CDS25904.1 - 0.049 14.0 39.5 0.17 12.2 7.4 4.6 4 0 0 4 4 4 0 Ring finger domain C1_2 PF03107.16 CDS25904.1 - 0.12 12.8 25.4 0.15 12.4 2.2 4.4 4 0 0 4 4 4 0 C1 domain C1_1 PF00130.22 CDS25904.1 - 0.59 10.1 33.5 0.12 12.3 2.1 4.6 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CDS25904.1 - 6.4 6.9 30.7 0.18 11.9 6.5 5.1 4 1 0 4 4 4 0 PHD-finger LAP1C PF05609.12 CDS25905.1 - 3 6.8 18.3 5.9 5.9 18.3 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ank_4 PF13637.6 CDS25907.2 - 4.8e-37 125.9 2.3 2.5e-13 50.2 0.0 5.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS25907.2 - 1.3e-34 118.7 0.1 3.2e-18 66.1 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS25907.2 - 1.4e-29 98.9 0.4 2.3e-05 24.4 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 CDS25907.2 - 2.1e-29 100.6 0.3 2.8e-07 30.7 0.4 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDS25907.2 - 5.3e-29 99.9 3.8 2.3e-08 34.1 0.0 5.5 3 2 2 6 6 6 4 Ankyrin repeats (many copies) BLOC1_2 PF10046.9 CDS25910.2 - 0.077 13.3 4.3 0.33 11.3 1.3 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Val_tRNA-synt_C PF10458.9 CDS25910.2 - 0.81 10.0 4.3 1.2e+02 3.1 0.7 4.0 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Synaptobrevin PF00957.21 CDS25910.2 - 3.5 7.5 6.1 2.7 7.9 0.6 3.7 3 0 0 3 3 3 0 Synaptobrevin DUF1673 PF07895.11 CDS25910.2 - 6.2 6.5 10.9 0.073 12.8 2.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) RFX_DNA_binding PF02257.15 CDS25912.1 - 4.5e-22 78.5 0.0 1.2e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain FPL PF09758.9 CDS25912.1 - 0.092 12.8 0.3 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein Methyltransf_32 PF13679.6 CDS25913.1 - 3.9e-16 59.4 0.1 1.1e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TRM13 PF05206.14 CDS25913.1 - 0.017 14.6 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Hist_deacetyl PF00850.19 CDS25914.1 - 2.8e-78 263.5 0.2 1.6e-77 261.0 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain Phage_int_SAM_5 PF13102.6 CDS25914.1 - 0.061 13.7 0.1 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Phage integrase SAM-like domain Formin_GBD_N PF18382.1 CDS25914.1 - 0.09 13.2 0.1 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain 2Fe-2S_thioredx PF01257.19 CDS25915.1 - 4e-56 188.9 0.0 4.6e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Pilus_CpaD PF09476.10 CDS25916.2 - 0.037 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2140 PF09911.9 CDS25916.2 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) RR_TM4-6 PF06459.12 CDS25916.2 - 0.17 11.7 4.6 0.21 11.4 4.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 CDS25916.2 - 0.37 9.3 11.0 0.46 9.0 11.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 CDS25916.2 - 0.38 11.0 5.8 0.44 10.9 5.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 CDS25916.2 - 3.5 5.7 15.8 4 5.5 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family Cse1 PF08506.10 CDS25917.1 - 8.7e-120 399.9 4.5 2.4e-119 398.5 0.5 2.8 2 1 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CDS25917.1 - 5.9e-85 285.4 10.9 1e-39 136.3 3.9 3.5 3 0 0 3 3 3 3 CAS/CSE protein, C-terminus IBN_N PF03810.19 CDS25917.1 - 1.9e-15 56.5 0.3 7.1e-15 54.7 0.3 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CDS25917.1 - 0.0052 16.9 2.9 0.72 9.9 0.0 3.7 3 1 1 4 4 4 2 Exportin 1-like protein DUF3437 PF11919.8 CDS25917.1 - 0.16 11.9 0.2 23 5.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Pkinase PF00069.25 CDS25918.1 - 2.7e-51 174.4 0.0 3.2e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25918.1 - 9.4e-35 120.1 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS25918.1 - 0.0054 16.1 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDS25918.1 - 0.0095 14.9 0.0 0.016 14.2 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDS25918.1 - 0.079 12.0 0.8 0.12 11.4 0.8 1.3 1 1 0 1 1 1 0 Seadornavirus VP7 Methyltransf_16 PF10294.9 CDS25919.1 - 3.6e-11 43.1 0.0 5.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF498 PF04430.14 CDS25920.1 - 6.7e-10 39.0 0.0 8.1e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) GFRP PF06399.13 CDS25920.1 - 0.023 14.6 0.0 0.072 13.0 0.0 1.8 1 1 1 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) WD40 PF00400.32 CDS25921.1 - 5.8e-07 30.1 7.3 0.013 16.3 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Methyltransf_25 PF13649.6 CDS25922.1 - 6.5e-09 36.4 0.0 1.1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS25922.1 - 7.3e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS25922.1 - 7.8e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS25922.1 - 1.6e-05 25.6 0.0 3.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS25922.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NCU-G1 PF15065.6 CDS25925.1 - 8.3e-47 159.9 2.7 1.1e-46 159.6 2.7 1.0 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 L_HMGIC_fpl PF10242.9 CDS25926.1 - 1.7e-28 100.1 13.7 2.3e-28 99.6 13.7 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CDS25926.1 - 1.4e-05 24.9 8.7 1.4e-05 24.9 8.7 2.5 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.12 CDS25926.1 - 0.0046 16.5 0.8 0.0046 16.5 0.8 1.7 2 0 0 2 2 2 1 Clc-like EF-hand_6 PF13405.6 CDS25927.1 - 0.043 13.8 0.1 7.8 6.7 0.1 2.9 2 1 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CDS25927.1 - 0.096 12.3 1.3 1.4 8.7 0.2 2.8 3 0 0 3 3 3 0 EF hand Homeodomain PF00046.29 CDS25928.1 - 3.8e-21 74.7 6.8 3.8e-21 74.7 6.8 2.1 2 0 0 2 2 2 1 Homeodomain EPO_TPO PF00758.18 CDS25928.1 - 0.0043 17.1 0.6 0.0077 16.3 0.6 1.4 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin EzrA PF06160.12 CDS25928.1 - 0.013 13.7 1.9 0.017 13.3 1.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Homez PF11569.8 CDS25928.1 - 0.36 10.3 2.2 0.79 9.2 1.2 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez RRM_5 PF13893.6 CDS25929.1 - 3.4e-32 110.7 0.1 1.8e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDS25929.1 - 3.2e-16 58.9 0.0 0.0012 18.7 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDS25929.1 - 9.4e-08 32.2 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RRM-like domain RL PF17797.1 CDS25929.1 - 0.0016 18.4 0.0 0.58 10.2 0.0 2.9 3 0 0 3 3 3 2 RL domain Limkain-b1 PF11608.8 CDS25929.1 - 0.078 13.1 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Limkain b1 NDK PF00334.19 CDS25930.1 - 2.1e-54 183.2 0.0 2.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 CDS25930.1 - 0.17 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ RINGv PF12906.7 CDS25931.1 - 1.8e-14 53.6 8.5 1.8e-14 53.6 8.5 1.9 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CDS25931.1 - 0.00096 19.4 5.5 0.00096 19.4 5.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS25931.1 - 0.012 15.4 5.8 0.046 13.6 5.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDS25931.1 - 0.016 15.4 7.0 0.6 10.3 1.6 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain DUF1673 PF07895.11 CDS25931.1 - 0.081 12.6 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Zn_ribbon_17 PF17120.5 CDS25931.1 - 0.12 12.0 3.6 0.26 10.9 3.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDS25931.1 - 0.14 12.3 4.5 0.099 12.7 2.7 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CDS25931.1 - 0.4 10.6 5.8 2.2 8.2 5.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LLGL PF08366.13 CDS25932.2 - 4.3e-20 72.0 0.0 1.5e-18 67.1 0.0 2.8 1 1 0 1 1 1 1 LLGL2 PQQ_3 PF13570.6 CDS25932.2 - 0.013 16.0 0.1 0.13 12.7 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain LSDAT_euk PF18139.1 CDS25933.1 - 1.8e-22 80.0 0.0 2.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM Ank_2 PF12796.7 CDS25933.1 - 3.9e-05 24.2 0.1 0.00057 20.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25933.1 - 0.033 14.8 0.3 4.7 7.9 0.1 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS25933.1 - 0.042 14.2 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS25933.1 - 0.062 13.9 0.2 6.2 7.7 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat DUF3012 PF11216.8 CDS25933.1 - 0.13 12.4 0.2 0.94 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Pkinase PF00069.25 CDS25934.2 - 9.5e-68 228.4 0.0 2.6e-67 227.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS25934.2 - 3e-27 95.5 0.0 4.9e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CDS25934.2 - 1.2e-14 54.6 0.5 2.9e-14 53.3 0.5 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.29 CDS25934.2 - 2.3e-05 24.9 0.6 0.00014 22.3 0.1 2.4 2 0 0 2 2 2 1 PH domain ANAPC_CDC26 PF10471.9 CDS25934.2 - 0.036 14.9 1.1 0.09 13.6 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Kinase-like PF14531.6 CDS25934.2 - 0.052 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Fis1_TPR_C PF14853.6 CDS25935.1 - 2.9e-16 59.3 0.5 1.5e-15 57.0 0.1 2.2 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDS25935.1 - 9.4e-06 25.4 2.0 6.8e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS25935.1 - 0.00024 20.8 2.3 0.00024 20.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS25935.1 - 0.0014 18.8 1.8 0.0021 18.2 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CDS25935.1 - 0.002 18.6 0.1 0.0044 17.5 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Mei4 PF13971.6 CDS25935.1 - 0.01 15.4 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 TPR_9 PF13371.6 CDS25935.1 - 0.014 15.5 0.1 0.034 14.3 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS25935.1 - 0.015 15.3 0.1 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS25935.1 - 0.03 14.5 1.2 0.093 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS25935.1 - 0.034 14.8 0.3 0.56 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS25935.1 - 0.06 13.7 0.5 0.16 12.3 0.2 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS25935.1 - 0.11 13.4 0.1 0.89 10.5 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Cm_res_leader PF08077.11 CDS25935.1 - 0.14 12.3 0.5 0.38 11.0 0.5 1.8 1 0 0 1 1 1 0 Chloramphenicol resistance gene leader peptide PGF-CTERM PF18204.1 CDS25935.1 - 7.2 6.7 12.8 0.78 9.8 7.7 2.1 2 0 0 2 2 2 0 PGF-CTERM motif Kunitz_BPTI PF00014.23 CDS25936.1 - 9.6e-122 397.2 152.3 1.1e-19 70.4 4.1 15.5 16 1 0 16 16 16 12 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.16 CDS25937.1 - 1.3e-58 195.0 0.0 2.7e-11 43.4 0.0 5.2 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS25937.1 - 1.1e-36 125.2 0.1 1.5e-06 28.7 0.0 5.8 6 0 0 6 6 6 5 Immunoglobulin domain Ig_2 PF13895.6 CDS25937.1 - 6e-19 68.2 0.1 0.025 14.9 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin domain ig PF00047.25 CDS25937.1 - 1.2e-17 63.9 0.2 4.3e-06 26.8 0.0 4.8 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 CDS25937.1 - 1.4e-15 57.4 0.1 6.8e-05 23.0 0.0 6.3 5 2 0 5 5 5 3 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 CDS25937.1 - 4.2e-10 39.8 0.0 0.2 11.9 0.0 4.4 4 0 0 4 4 4 3 Natural killer cell receptor 2B4 Ig_6 PF18452.1 CDS25937.1 - 1.5e-07 30.9 0.7 0.73 9.4 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain BiPBP_C PF06832.12 CDS25937.1 - 1.4e-05 25.0 0.0 2.9 8.0 0.0 5.7 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 CDS25937.1 - 0.00091 19.2 0.0 3.4 7.8 0.0 4.3 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain HMG_box PF00505.19 CDS25938.1 - 6.8e-27 93.7 1.4 1.2e-26 92.9 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS25938.1 - 9.4e-11 42.2 0.6 1.7e-10 41.3 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain Ank_2 PF12796.7 CDS25939.1 - 7.6e-72 237.9 30.3 4.6e-15 56.0 0.2 8.3 2 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS25939.1 - 1.2e-57 191.6 26.3 2.3e-09 37.6 0.2 10.4 6 2 6 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 CDS25939.1 - 8.3e-53 174.6 33.5 0.00033 21.0 0.1 15.4 14 1 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.6 CDS25939.1 - 4.1e-49 158.8 29.6 0.00017 21.7 0.0 16.3 17 0 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.6 CDS25939.1 - 2.3e-48 161.6 24.9 5.8e-07 29.7 0.0 12.7 7 3 5 13 13 13 11 Ankyrin repeats (many copies) Ion_trans PF00520.31 CDS25939.1 - 5.5e-06 25.8 16.6 8.2e-06 25.2 16.6 1.2 1 0 0 1 1 1 1 Ion transport protein Sacchrp_dh_NADP PF03435.18 CDS25939.1 - 0.0017 18.6 0.1 0.19 12.0 0.1 2.7 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Gal-bind_lectin PF00337.22 CDS25942.1 - 1.4e-06 27.9 0.0 3.2e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Galactoside-binding lectin Actin PF00022.19 CDS25943.2 - 2.1e-36 125.4 0.0 3.9e-28 98.2 0.0 2.7 3 0 0 3 3 3 2 Actin JmjC PF02373.22 CDS25944.1 - 1.2e-09 38.6 0.0 3.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CDS25944.1 - 0.16 11.7 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Cupin domain zf-C5HC2 PF02928.16 CDS25944.1 - 0.16 12.4 7.9 0.64 10.4 7.9 2.1 1 0 0 1 1 1 0 C5HC2 zinc finger zf-UBP PF02148.19 CDS25944.1 - 0.27 11.6 6.2 0.83 10.0 6.2 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Baculo_IE-1 PF05290.11 CDS25944.1 - 0.28 11.1 3.5 0.66 9.9 3.5 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 CDS25944.1 - 0.7 10.1 10.5 0.026 14.6 1.8 2.8 2 1 0 2 2 2 0 FYVE zinc finger DUF2635 PF10948.8 CDS25945.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2635) zf-C2H2 PF00096.26 CDS25948.1 - 0.05 14.1 2.3 0.11 13.0 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS25948.1 - 0.27 12.2 1.8 0.78 10.8 1.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C4 PF00105.18 CDS25950.1 - 8.5e-17 61.4 9.7 1.7e-16 60.4 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.9 CDS25950.1 - 0.047 13.8 0.5 0.094 12.8 0.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-RRPl_C4 PF17026.5 CDS25950.1 - 0.3 11.2 4.5 0.61 10.2 4.5 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Hydrolase_6 PF13344.6 CDS25952.1 - 2.4e-26 91.8 0.0 7.2e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDS25952.1 - 1.6e-16 60.1 0.0 2.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CDS25952.1 - 1.6e-10 41.6 0.1 9.5e-09 35.8 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDS25952.1 - 8e-08 32.6 0.8 0.00071 19.7 0.0 3.3 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDS25952.1 - 9.2e-05 22.3 0.0 0.00081 19.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDS25952.1 - 0.0004 20.0 0.2 0.0032 17.1 0.1 2.3 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase HAD PF12710.7 CDS25952.1 - 0.025 15.0 0.5 5.9 7.3 0.4 3.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase GIT1_C PF12205.8 CDS25953.1 - 7.3e-29 100.3 0.2 7.3e-29 100.3 0.2 2.8 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term ArfGap PF01412.18 CDS25953.1 - 1.4e-23 83.2 0.0 8.8e-23 80.6 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf GIT_SHD PF08518.11 CDS25953.1 - 9.4e-21 73.1 3.7 9.2e-11 41.2 0.4 2.4 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Ank_4 PF13637.6 CDS25953.1 - 0.0014 19.2 0.0 0.0039 17.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS25953.1 - 0.0039 17.8 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) CALCOCO1 PF07888.11 CDS25953.1 - 0.006 15.5 6.8 0.0096 14.8 6.8 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HAP1_N PF04849.13 CDS25953.1 - 0.0069 15.6 3.5 0.013 14.7 3.5 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TSC22 PF01166.18 CDS25953.1 - 0.0093 16.3 0.1 0.025 14.9 0.1 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family Med4 PF10018.9 CDS25953.1 - 0.052 13.2 1.8 7 6.3 0.3 2.5 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4164 PF13747.6 CDS25953.1 - 0.07 13.4 6.9 0.22 11.8 6.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Ank_5 PF13857.6 CDS25953.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ax_dynein_light PF10211.9 CDS25953.1 - 0.084 12.8 3.5 0.17 11.8 3.5 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain APG6_N PF17675.1 CDS25953.1 - 0.11 13.0 7.3 0.25 11.8 7.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region CtIP_N PF10482.9 CDS25953.1 - 0.12 12.4 2.0 0.27 11.3 2.0 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Cep57_CLD_2 PF14197.6 CDS25953.1 - 0.17 12.0 8.2 0.9 9.7 8.2 2.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Cluap1 PF10234.9 CDS25953.1 - 0.32 10.4 3.5 0.71 9.2 3.5 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 HAUS-augmin3 PF14932.6 CDS25953.1 - 0.48 10.0 4.6 1.1 8.8 4.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CDS25953.1 - 1 8.2 5.2 1.7 7.5 5.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Integrase_H2C2 PF17921.1 CDS25955.1 - 7.4e-17 61.2 0.8 1.1e-16 60.6 0.8 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDS25955.1 - 0.00017 21.8 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDS25955.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger La PF05383.17 CDS25955.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 La domain DUF2990 PF11693.8 CDS25955.1 - 0.036 14.2 0.0 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) RT_RNaseH_2 PF17919.1 CDS25956.1 - 2.3e-24 85.3 0.5 3.7e-24 84.6 0.5 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS25956.1 - 3.9e-24 84.9 0.1 6.7e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS25956.1 - 4.8e-08 32.8 0.7 0.00079 19.0 0.0 3.1 3 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mgr1 PF08602.10 CDS25956.1 - 0.042 12.7 0.4 0.075 11.9 0.1 1.5 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit gag-asp_proteas PF13975.6 CDS25957.1 - 0.00097 19.7 0.0 0.012 16.1 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS25957.1 - 0.0091 16.6 0.0 0.032 14.9 0.0 2.0 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.20 CDS25957.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease AAA_34 PF13872.6 CDS25958.1 - 2.6e-136 453.4 0.0 5e-136 452.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 CDS25958.1 - 6.9e-114 380.1 0.1 1.1e-113 379.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 CDS25958.1 - 1.1e-05 25.6 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 CDS25958.1 - 4 5.6 10.6 8.8 4.5 10.6 1.5 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CDS25958.1 - 6.6 4.7 13.1 11 4.0 13.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 CDS25958.1 - 9.7 4.5 8.7 16 3.8 8.7 1.2 1 0 0 1 1 1 0 SGT1 protein BCS1_N PF08740.11 CDS25959.1 - 3.7e-40 137.9 0.3 6.6e-40 137.1 0.1 1.5 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDS25959.1 - 8.8e-20 71.5 0.0 1.4e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS25959.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CDS25959.1 - 0.0019 18.6 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CDS25959.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CDS25959.1 - 0.033 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 CDS25959.1 - 0.034 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDS25959.1 - 0.042 14.4 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 CDS25959.1 - 0.048 14.2 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDS25959.1 - 0.051 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS25959.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDS25959.1 - 0.058 13.5 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDS25959.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 CDS25959.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CDS25959.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CDS25959.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDS25959.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 CDS25959.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Cullin PF00888.22 CDS25960.1 - 1.6e-93 314.4 7.8 1.3e-85 288.3 1.3 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 CDS25960.1 - 1.3e-16 60.3 0.3 6.2e-16 58.2 0.1 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain nsp9 PF08710.10 CDS25960.1 - 0.15 12.5 0.4 0.8 10.1 0.2 2.1 2 0 0 2 2 2 0 nsp9 replicase PK PF00224.21 CDS25961.1 - 2.2e-154 513.5 0.1 3.2e-154 513.0 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Innexin PF00876.18 CDS25961.1 - 6.4e-67 226.3 3.5 1.3e-66 225.3 3.5 1.4 1 1 0 1 1 1 1 Innexin PK_C PF02887.16 CDS25961.1 - 3.4e-30 104.7 0.1 7.6e-30 103.5 0.1 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDS25961.1 - 0.047 12.8 0.3 0.13 11.4 0.3 1.7 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CDS25961.1 - 0.07 12.1 0.0 0.64 9.0 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF3112 PF11309.8 CDS25961.1 - 0.54 9.7 2.6 15 5.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) ATP-synt_ab PF00006.25 CDS25962.1 - 1.4e-68 230.8 0.0 2e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDS25962.1 - 7.4e-14 52.0 0.5 1.3e-13 51.3 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain zf-LITAF-like PF10601.9 CDS25963.1 - 1e-19 70.6 11.7 1.3e-19 70.2 11.7 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain UPF0547 PF10571.9 CDS25963.1 - 0.14 12.2 3.3 3.2 7.9 0.5 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C4_Topoisom PF01396.19 CDS25963.1 - 0.19 11.6 3.7 1.6 8.6 1.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ACC PF17848.1 CDS25963.1 - 0.28 11.3 8.1 8.4 6.6 0.2 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Zn-ribbon_8 PF09723.10 CDS25963.1 - 0.75 10.0 0.2 0.75 10.0 0.2 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CDS25963.1 - 1.3 9.0 5.1 15 5.6 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 CDS25963.1 - 7.9 6.3 8.5 8.6 6.2 0.1 2.9 3 0 0 3 3 3 0 InsA N-terminal domain Tetraspanin PF00335.20 CDS25965.1 - 8.5e-26 91.1 11.8 1e-25 90.8 11.8 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4042 PF13251.6 CDS25965.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) GAPT PF11770.8 CDS25965.1 - 1.1 9.2 2.8 6 6.7 0.7 2.3 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Tetraspanin PF00335.20 CDS25966.1 - 1.5e-30 106.6 27.8 2.5e-30 105.9 27.8 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 CDS25966.1 - 2.2 8.0 7.1 2.9 7.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MFS_2 PF13347.6 CDS25966.1 - 2.7 6.5 15.8 0.44 9.0 10.8 1.8 2 0 0 2 2 2 0 MFS/sugar transport protein Tetraspanin PF00335.20 CDS25967.2 - 3.6e-42 144.6 11.1 4.1e-42 144.4 11.1 1.0 1 0 0 1 1 1 1 Tetraspanin family UPF0242 PF06785.11 CDS25967.2 - 0.028 14.5 0.4 0.12 12.4 0.1 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF973 PF06157.11 CDS25967.2 - 0.057 12.5 10.2 0.019 14.0 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Phage_holin_3_6 PF07332.11 CDS25967.2 - 0.49 10.5 12.2 0.062 13.3 4.0 2.6 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 CDS25967.2 - 0.7 8.6 7.5 1.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2976 PF11190.8 CDS25967.2 - 5.2 6.9 13.0 5.2 7.0 0.9 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) Usp PF00582.26 CDS25968.1 - 4.7e-24 85.5 0.0 1.5e-23 83.9 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family SET PF00856.28 CDS25969.1 - 1.4e-07 32.1 0.1 7.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 SET domain YidD PF01809.18 CDS25969.1 - 4.2 7.3 9.7 1.5 8.8 6.4 2.0 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor Motile_Sperm PF00635.26 CDS25970.1 - 0.05 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain RPAP1_N PF08621.10 CDS25970.1 - 0.065 13.0 0.1 4.1 7.2 0.1 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal COE1_DBD PF16422.5 CDS25971.1 - 8e-124 411.6 3.7 1.5e-123 410.7 3.7 1.4 1 0 0 1 1 1 1 Transcription factor COE1 DNA-binding domain COE1_HLH PF16423.5 CDS25971.1 - 1e-28 98.8 1.0 1.8e-28 97.9 1.0 1.4 1 0 0 1 1 1 1 Transcription factor COE1 helix-loop-helix domain TIG PF01833.24 CDS25971.1 - 9.8e-15 54.4 0.2 3e-14 52.9 0.2 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ribosomal_L6 PF00347.23 CDS25972.1 - 4.8e-28 97.6 3.1 1.3e-19 70.6 2.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 KH_1 PF00013.29 CDS25972.1 - 0.031 14.1 0.2 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 KH domain HCBP_related PF06594.11 CDS25972.1 - 0.21 11.6 0.2 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain zf-C2H2 PF00096.26 CDS25973.1 - 0.016 15.7 18.4 0.12 12.8 0.1 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4054 PF13262.6 CDS25973.1 - 0.11 12.5 0.8 0.36 10.9 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) zf-C2H2_2 PF12756.7 CDS25973.1 - 0.22 11.8 4.2 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDS25973.1 - 0.23 12.4 0.1 0.23 12.4 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 CDS25973.1 - 4.8 7.2 10.4 0.34 10.9 3.3 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2HE PF16278.5 CDS25973.1 - 6 7.4 7.5 11 6.6 0.1 3.4 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger TPR_19 PF14559.6 CDS25975.1 - 6.6e-08 33.0 0.0 0.081 13.4 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS25975.1 - 0.18 12.7 2.2 2.9 9.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS25975.1 - 0.18 12.0 5.9 83 3.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS25975.1 - 0.67 10.3 5.4 44 4.5 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS25975.1 - 2.5 8.4 8.2 24 5.2 0.0 4.8 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Nop PF01798.18 CDS25976.1 - 1.8e-75 253.3 0.2 2.8e-75 252.8 0.2 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CDS25976.1 - 6.5e-42 143.3 0.2 1.3e-41 142.3 0.2 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nup192 PF11894.8 CDS25977.1 - 1.5e-130 436.8 0.0 4.9e-130 435.1 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Molybdopterin PF00384.22 CDS25977.1 - 9.3e-62 209.4 0.0 3.9e-61 207.3 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CDS25977.1 - 1.3e-16 60.4 0.2 2.9e-16 59.3 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CDS25977.1 - 2.2e-15 55.9 0.1 5.3e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 CDS25977.1 - 3.5e-08 34.0 0.4 1.2e-07 32.3 0.4 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 CDS25977.1 - 4.2e-07 29.8 0.8 1.3e-06 28.3 0.8 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 CDS25977.1 - 0.0045 16.7 0.2 0.074 12.8 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain RHH_3 PF12651.7 CDS25977.1 - 0.18 11.8 0.0 0.51 10.3 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain UPF0489 PF12640.7 CDS25978.1 - 5.3e-38 131.0 0.0 8.3e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain Rad17 PF03215.15 CDS25982.1 - 6e-08 32.8 0.0 2.6e-06 27.5 0.0 2.6 1 1 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 CDS25982.1 - 1.3e-05 25.6 0.3 9.8e-05 22.8 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CDS25982.1 - 0.0023 18.0 0.0 0.88 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CDS25982.1 - 0.067 13.7 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CDS25982.1 - 0.083 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS25982.1 - 0.086 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 CDS25982.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase RsgA_GTPase PF03193.16 CDS25982.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 CDS25982.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 CDS25982.1 - 0.15 12.1 0.0 0.48 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SNF PF00209.18 CDS25985.1 - 2.7e-171 570.8 36.8 3.1e-171 570.6 36.8 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family G-patch_2 PF12656.7 CDS25985.1 - 0.2 11.8 0.7 0.44 10.7 0.7 1.4 1 0 0 1 1 1 0 G-patch domain MA3 PF02847.17 CDS25986.1 - 2.9e-09 36.9 0.3 9.7e-06 25.5 0.0 2.8 2 0 0 2 2 2 2 MA3 domain E1_DerP2_DerF2 PF02221.15 CDS25987.1 - 4e-20 72.6 1.0 1.5e-19 70.7 0.5 2.2 2 0 0 2 2 2 1 ML domain Ras PF00071.22 CDS25987.1 - 5.6e-11 42.3 0.0 4.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDS25987.1 - 3.5e-08 33.7 0.0 1.8e-06 28.2 0.0 2.3 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_35 PF14516.6 CDS25987.1 - 0.044 12.6 0.0 4.7 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 CDS25987.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 CDS25987.1 - 0.13 11.7 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS25988.1 - 5.5e-43 146.8 0.0 8.1e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CDS25988.1 - 3.4e-33 114.8 4.4 6e-33 114.0 4.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CDS25988.1 - 6.2e-24 84.1 0.0 2.4e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDS25988.1 - 1.1e-22 79.9 0.0 3.3e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDS25988.1 - 3.2e-11 43.5 0.0 6.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CDS25988.1 - 1.3e-07 31.6 0.0 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CDS25988.1 - 0.0035 17.4 0.0 0.0069 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDS25988.1 - 0.013 15.7 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS25988.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 CDS25988.1 - 0.18 11.7 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Ribosom_S12_S23 PF00164.25 CDS25989.1 - 8.6e-43 144.6 0.4 9.4e-43 144.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PIH1 PF08190.12 CDS25990.1 - 2.6e-22 79.1 0.2 6.7e-15 54.9 0.0 2.5 2 0 0 2 2 2 2 PIH1 N-terminal domain PIH1_CS PF18201.1 CDS25990.1 - 1.3e-17 64.0 0.1 4.4e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain FERM_M PF00373.18 CDS25990.1 - 1.8e-11 44.5 0.0 1e-10 42.0 0.0 2.4 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CDS25990.1 - 3.1e-09 37.1 0.2 8.1e-09 35.8 0.2 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDS25990.1 - 6e-08 32.5 0.2 2.5e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain BEN PF10523.9 CDS25991.1 - 0.0005 20.2 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 BEN domain NADHdh-2_N PF12155.8 CDS25992.1 - 0.049 14.0 0.6 0.15 12.5 0.6 1.8 1 1 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal TctB PF07331.11 CDS25992.1 - 0.32 11.3 16.8 0.15 12.3 6.6 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cpn60_TCP1 PF00118.24 CDS25993.1 - 3.4e-145 484.4 10.4 3.9e-145 484.2 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YqaH PF17448.2 CDS25993.1 - 0.013 15.8 0.3 0.085 13.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized YqaH-like PrpR_N PF06506.11 CDS25993.1 - 0.019 14.6 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Pox_E6 PF04656.12 CDS25993.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Pox virus E6 protein DUF3395 PF11875.8 CDS25994.1 - 2.5e-32 111.9 0.0 4e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CDS25994.1 - 5.1e-21 74.6 0.1 9.2e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain ECH_1 PF00378.20 CDS25995.1 - 1.1e-31 110.0 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDS25995.1 - 1.6e-15 57.4 0.0 3.4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HrcA_DNA-bdg PF03444.15 CDS25995.1 - 0.087 12.5 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Auxin_repressed PF05564.12 CDS25995.1 - 2.3 8.9 5.5 1.9 9.2 0.2 2.6 3 0 0 3 3 3 0 Dormancy/auxin associated protein DEAD PF00270.29 CDS25996.1 - 1.5e-48 164.8 0.0 3e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS25996.1 - 1.4e-27 96.2 0.0 5.6e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CDS25996.1 - 5.1e-20 71.6 0.0 2.1e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 CDS25996.1 - 0.00021 20.6 0.0 0.00043 19.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CDS25996.1 - 0.00023 21.2 0.0 0.00071 19.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDS25996.1 - 0.00026 20.4 2.8 0.00074 18.9 0.1 2.6 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit zf-Di19 PF05605.12 CDS25997.1 - 0.00018 21.7 6.5 0.0063 16.8 2.5 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDS25997.1 - 0.0053 17.5 9.1 0.51 11.3 2.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 CDS25997.1 - 0.21 11.5 0.9 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 CDS25997.1 - 1.8 9.1 9.0 0.37 11.3 3.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-FCS PF06467.14 CDS25997.1 - 2.9 7.9 6.5 5 7.1 0.6 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Macro PF01661.21 CDS25998.1 - 1.3e-24 86.5 0.1 2.4e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone PF00125.24 CDS25998.1 - 1.1e-11 45.2 0.1 2.7e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDS25998.1 - 2.7e-07 30.2 0.0 6.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDS25998.1 - 1.2e-06 28.7 0.1 4.7e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.22 CDS25999.1 - 1.1e-05 25.1 0.0 0.035 13.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDS26000.1 - 3e-06 26.9 0.1 0.0036 17.1 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS26000.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif Pkinase PF00069.25 CDS26001.2 - 1.7e-63 214.5 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26001.2 - 2.3e-46 158.2 0.0 3.3e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.8 CDS26001.2 - 6.9e-15 54.9 0.1 1.3e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Pkinase_fungal PF17667.1 CDS26001.2 - 5.2e-05 22.2 0.0 0.00011 21.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF4952 PF16310.5 CDS26001.2 - 0.036 14.3 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) UQ_con PF00179.26 CDS26004.1 - 3.5e-19 68.9 0.6 9.2e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDS26006.2 - 1.4e-14 53.9 0.1 2.8e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WD40 PF00400.32 CDS26008.1 - 1.8e-14 53.9 2.7 0.00028 21.6 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS26008.1 - 1.4e-10 41.3 0.0 0.0023 18.2 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CDS26008.1 - 0.008 15.3 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 CDS26008.1 - 0.0086 16.0 0.0 0.6 10.0 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A CH PF00307.31 CDS26009.1 - 0.14 12.4 2.7 4.1 7.6 0.1 2.9 2 1 1 3 3 3 0 Calponin homology (CH) domain DUF2258 PF10015.9 CDS26009.1 - 0.2 11.8 0.6 0.65 10.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DUF5344 PF17279.2 CDS26009.1 - 1.1 9.9 4.8 15 6.3 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5344) RRM_1 PF00076.22 CDS26010.1 - 1.8e-17 62.9 0.1 9.4e-10 38.2 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDS26010.1 - 5.3e-06 26.5 0.0 2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CDS26010.1 - 0.091 12.4 0.0 2.4 7.7 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS26010.1 - 0.12 12.3 0.1 0.44 10.4 0.0 2.0 2 1 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 CDS26012.2 - 4.1e-27 93.8 0.3 2.3e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDS26012.2 - 0.042 13.9 0.1 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 DUF1202 PF06717.11 CDS26012.2 - 0.073 12.5 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) RRM_1 PF00076.22 CDS26013.2 - 4.8e-79 260.2 4.7 5.1e-20 71.1 0.5 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDS26013.2 - 3.1e-12 46.5 0.0 8.1e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.11 CDS26013.2 - 2.7e-06 27.3 4.7 2.7 8.1 0.2 4.9 4 1 1 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.6 CDS26013.2 - 4.4e-06 26.6 3.0 1.3 9.1 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDS26013.2 - 6e-06 26.3 0.1 0.63 10.2 0.0 5.0 4 3 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 CDS26013.2 - 0.00027 21.0 0.0 1.8 8.7 0.0 3.7 4 0 0 4 4 4 2 Limkain b1 RRM_occluded PF16842.5 CDS26013.2 - 0.00095 19.0 0.0 0.45 10.4 0.0 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif SET_assoc PF11767.8 CDS26013.2 - 0.0067 16.1 0.6 11 5.7 0.2 4.2 4 1 0 4 4 4 1 Histone lysine methyltransferase SET associated DHHA1 PF02272.19 CDS26013.2 - 0.14 12.5 0.6 0.57 10.6 0.2 2.2 2 1 0 2 2 2 0 DHHA1 domain OB_RNB PF08206.11 CDS26013.2 - 0.66 9.7 6.0 8.4 6.2 0.2 3.8 4 0 0 4 4 4 0 Ribonuclease B OB domain PCI PF01399.27 CDS26014.1 - 3.8e-14 53.1 2.0 4.9e-13 49.5 0.2 2.9 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 CDS26014.1 - 1.5e-07 31.3 2.1 1.5e-07 31.3 0.5 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 ST7 PF04184.12 CDS26014.1 - 0.0082 14.7 0.2 0.011 14.2 0.2 1.3 1 0 0 1 1 1 1 ST7 protein HIGH_NTase1_ass PF16581.5 CDS26014.1 - 0.034 14.1 1.3 1.1 9.2 0.1 3.0 2 1 0 3 3 3 0 Cytidyltransferase-related C-terminal region SMP_2 PF10144.9 CDS26014.1 - 0.08 12.6 1.0 0.53 9.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial virulence factor haemolysin AMP-binding PF00501.28 CDS26015.1 - 1.1e-37 129.7 0.0 2.9e-37 128.3 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CDS26015.1 - 1.4e-07 31.7 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Cpn60_TCP1 PF00118.24 CDS26015.1 - 0.024 13.3 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Adaptin_binding PF10199.9 CDS26016.2 - 2.6e-07 31.2 2.4 1.7e-06 28.7 2.4 2.0 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Innexin PF00876.18 CDS26017.1 - 4.7e-106 355.0 12.5 5.3e-106 354.8 12.5 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 CDS26017.1 - 4 6.9 8.3 0.23 11.0 0.4 2.5 3 0 0 3 3 3 0 Super-infection exclusion protein B Innexin PF00876.18 CDS26018.2 - 2.7e-145 484.1 0.1 3.5e-145 483.7 0.1 1.1 1 0 0 1 1 1 1 Innexin Pkinase PF00069.25 CDS26019.1 - 2.8e-48 164.6 0.0 4.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26019.1 - 1.6e-16 60.4 0.0 2.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26019.1 - 7.3e-08 32.1 0.0 2.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDS26019.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS26019.1 - 0.00054 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS26019.1 - 0.11 11.4 0.7 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 CDS26019.1 - 0.17 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase REV PF00424.18 CDS26020.1 - 0.0023 17.9 6.5 0.22 11.6 1.7 2.3 2 0 0 2 2 2 2 REV protein (anti-repression trans-activator protein) MCM2_N PF12619.8 CDS26020.1 - 0.04 14.2 2.9 2.2 8.6 0.8 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 TraV PF09676.10 CDS26020.1 - 0.11 13.5 0.7 0.11 13.5 0.7 2.1 1 1 1 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) RP-C_C PF11800.8 CDS26020.1 - 2.3 8.3 6.3 3 7.9 6.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2956 PF11169.8 CDS26020.1 - 3.2 8.0 14.0 4.8 7.4 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) ADIP PF11559.8 CDS26021.1 - 0.0036 17.4 1.2 0.0064 16.6 1.2 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Med9 PF07544.13 CDS26021.1 - 0.069 13.2 2.7 0.12 12.5 0.9 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-B_box PF00643.24 CDS26024.2 - 1.6e-05 25.0 4.1 2.8e-05 24.2 1.5 2.1 2 0 0 2 2 2 1 B-box zinc finger IBR PF01485.21 CDS26024.2 - 0.0064 16.7 1.1 0.015 15.5 1.1 1.6 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain PHD PF00628.29 CDS26024.2 - 0.0077 16.1 3.9 0.025 14.5 1.7 2.1 2 0 0 2 2 2 1 PHD-finger zf-Sec23_Sec24 PF04810.15 CDS26024.2 - 0.026 14.6 1.5 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn_Tnp_IS91 PF14319.6 CDS26024.2 - 0.079 13.0 1.6 0.24 11.5 0.8 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain Dynactin_p62 PF05502.13 CDS26024.2 - 0.24 10.1 1.7 0.52 9.0 0.4 1.9 2 0 0 2 2 2 0 Dynactin p62 family Prok-RING_4 PF14447.6 CDS26024.2 - 0.32 10.9 6.9 1.1 9.2 0.1 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDS26024.2 - 0.44 10.5 7.5 7.6 6.6 3.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDS26024.2 - 0.77 9.7 0.1 0.77 9.7 0.1 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 CDS26024.2 - 0.78 10.1 5.6 34 4.9 0.0 2.2 2 0 0 2 2 2 0 C1 domain zinc_ribbon_9 PF14369.6 CDS26024.2 - 1.6 9.1 8.2 28 5.1 0.0 2.9 2 1 0 2 2 2 0 zinc-ribbon zf-RING_7 PF02591.15 CDS26024.2 - 4.3 7.6 11.9 1.3e+02 2.9 0.1 3.9 2 1 0 2 2 2 0 C4-type zinc ribbon domain LEM PF03020.15 CDS26025.1 - 2.9e-06 26.7 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 LEM domain DUF4549 PF15082.6 CDS26026.1 - 3.3e-34 117.7 0.5 5.8e-34 116.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) DUF4369 PF14289.6 CDS26026.1 - 0.14 12.7 0.0 1.9 9.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4369) HD PF01966.22 CDS26029.2 - 0.024 14.8 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 HD domain Arf PF00025.21 CDS26035.1 - 7.2e-72 240.5 0.1 7.9e-72 240.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS26035.1 - 1.1e-13 51.4 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS26035.1 - 4.3e-12 45.9 0.1 5e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDS26035.1 - 2.9e-10 39.9 0.5 1.2e-06 27.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDS26035.1 - 5.3e-09 35.8 0.0 6.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS26035.1 - 8.9e-09 35.0 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDS26035.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CDS26035.1 - 0.0012 19.3 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDS26035.1 - 0.013 16.0 0.2 0.052 14.1 0.2 1.9 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CDS26035.1 - 0.016 15.1 0.1 5.6 6.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CDS26035.1 - 0.029 14.1 0.1 2.3 8.0 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CDS26035.1 - 0.046 12.7 0.1 2.2 7.2 0.0 2.3 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CDS26035.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain tRNA-synt_1b PF00579.25 CDS26036.1 - 1.3e-19 70.6 0.0 3.7e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) FERM_M PF00373.18 CDS26037.1 - 5.7e-11 42.9 0.1 5.7e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CDS26037.1 - 1.7e-07 31.5 0.0 5e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDS26037.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FERM N-terminal domain BTB PF00651.31 CDS26038.1 - 2e-19 69.9 0.3 8.3e-19 67.9 0.1 2.1 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CDS26038.1 - 1.5e-06 28.3 0.0 3.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 MATH domain PIP5K PF01504.18 CDS26040.1 - 1.2e-49 169.0 0.0 3.1e-49 167.7 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ion_trans_2 PF07885.16 CDS26041.2 - 2.4e-17 62.6 2.8 2.4e-17 62.6 2.8 1.6 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 CDS26041.2 - 0.0075 15.5 0.1 0.069 12.4 0.0 2.0 2 0 0 2 2 2 1 Ion transport protein FlxA PF14282.6 CDS26041.2 - 0.082 12.9 0.8 0.25 11.3 0.8 1.8 1 0 0 1 1 1 0 FlxA-like protein ABC_tran_CTD PF16326.5 CDS26041.2 - 0.12 12.6 0.2 0.36 11.1 0.1 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain Homeodomain PF00046.29 CDS26043.1 - 7.5e-22 76.9 2.4 1.9e-21 75.7 2.4 1.7 1 0 0 1 1 1 1 Homeodomain Cep57_CLD_2 PF14197.6 CDS26043.1 - 0.028 14.5 1.2 0.048 13.8 1.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Homeobox_KN PF05920.11 CDS26043.1 - 0.045 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain Type2_restr_D3 PF16902.5 CDS26044.1 - 0.1 12.5 0.3 0.1 12.5 0.3 3.0 3 1 1 4 4 4 0 Type-2 restriction enzyme D3 domain GAS PF13851.6 CDS26044.1 - 0.5 9.7 50.5 0.29 10.5 15.2 4.2 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding UPF0270 PF06794.12 CDS26044.1 - 1.4 9.1 5.0 1.1 9.4 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) DUF3138 PF11336.8 CDS26044.1 - 2.5 6.6 8.0 5.7 5.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ABC1 PF03109.16 CDS26045.1 - 8.2e-32 109.9 0.0 1.3e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 CDS26045.1 - 0.047 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) MEA1 PF06910.11 CDS26046.1 - 2.7e-24 86.2 7.1 1.1e-23 84.2 6.5 1.9 1 1 1 2 2 2 2 Male enhanced antigen 1 (MEA1) zf-Di19 PF05605.12 CDS26047.1 - 1.1e-05 25.6 1.3 1.1e-05 25.6 1.3 6.5 6 1 0 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CDS26047.1 - 0.0013 19.4 51.1 0.035 14.9 0.1 8.8 10 0 0 10 10 10 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS26047.1 - 0.039 14.4 1.4 0.039 14.4 1.4 7.3 10 0 0 10 10 10 0 Zinc finger, C2H2 type REF PF05755.12 CDS26047.1 - 0.045 13.6 4.2 0.092 12.6 4.2 1.4 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) zf-H2C2_2 PF13465.6 CDS26047.1 - 0.093 13.2 25.5 2.8 8.5 0.4 7.8 8 1 0 8 8 8 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDS26047.1 - 1.4 8.8 16.9 2.3 8.1 0.7 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-met PF12874.7 CDS26047.1 - 3.9 8.0 27.8 0.92 10.0 0.2 6.1 7 0 0 7 7 7 0 Zinc-finger of C2H2 type AAA_23 PF13476.6 CDS26047.1 - 7.8 6.9 7.5 4.9 7.6 5.0 1.9 2 0 0 2 2 2 0 AAA domain zf-CCHC_2 PF13696.6 CDS26047.1 - 7.8 6.4 12.4 39 4.2 1.3 3.7 3 0 0 3 3 3 0 Zinc knuckle RIIa PF02197.17 CDS26048.1 - 3.2e-11 42.7 0.2 4.5e-11 42.2 0.2 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Rpn3_C PF08375.11 CDS26049.1 - 1.5e-24 86.2 1.0 3e-24 85.2 1.0 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CDS26049.1 - 1.3e-21 77.1 0.6 5.3e-21 75.1 0.1 2.3 2 1 1 3 3 3 1 PCI domain ArnB_C PF18677.1 CDS26049.1 - 0.1 12.7 1.1 0.6 10.2 0.0 2.8 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain DUF3510 PF12022.8 CDS26049.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Amidase PF01425.21 CDS26050.1 - 2.4e-84 283.9 0.0 2.7e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Amidase PDZ PF00595.24 CDS26051.1 - 7.8e-16 58.2 0.0 2.6e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDS26051.1 - 2.2e-14 53.0 0.0 5.3e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS26051.1 - 3.2e-05 24.2 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tfb4 PF03850.14 CDS26052.2 - 4e-52 177.4 0.0 4.2e-30 105.2 0.0 2.2 1 1 1 2 2 2 2 Transcription factor Tfb4 FtsJ PF01728.19 CDS26052.2 - 3.1e-31 108.8 0.0 8.7e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase G-patch PF01585.23 CDS26052.2 - 1.8e-11 43.7 3.5 3.1e-11 43.0 3.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS26052.2 - 0.00039 20.4 0.8 0.00074 19.5 0.8 1.4 1 0 0 1 1 1 1 G-patch domain Alliinase_C PF04864.13 CDS26052.2 - 0.083 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Allinase EGF PF00008.27 CDS26054.1 - 5.8e-67 221.5 247.6 3.5e-08 33.6 7.5 19.4 19 1 0 19 19 19 15 EGF-like domain hEGF PF12661.7 CDS26054.1 - 2.2e-39 132.7 194.7 4.7e-06 27.0 4.2 19.1 17 0 0 17 17 17 15 Human growth factor-like EGF DSL PF01414.19 CDS26054.1 - 3.4e-15 56.1 5.8 3.4e-15 56.1 5.8 14.4 12 3 4 16 16 16 3 Delta serrate ligand EGF_2 PF07974.13 CDS26054.1 - 2.1e-11 44.0 304.7 0.0027 18.1 6.2 19.6 20 0 0 20 20 20 16 EGF-like domain EGF_CA PF07645.15 CDS26054.1 - 2.6e-06 27.5 40.8 0.00018 21.7 6.0 19.1 8 4 12 20 20 20 9 Calcium-binding EGF domain AAA_12 PF13087.6 CDS26055.1 - 1.5e-38 132.4 0.0 2.5e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDS26055.1 - 1.8e-28 100.1 0.4 1.7e-13 51.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDS26055.1 - 2e-15 57.0 0.0 4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 CDS26055.1 - 4.7e-13 49.4 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_19 PF13245.6 CDS26055.1 - 3e-12 47.1 0.0 6.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDS26055.1 - 2.5e-07 30.7 0.1 0.46 10.2 0.0 4.5 4 1 0 4 4 4 2 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 CDS26055.1 - 1.6e-05 25.0 0.2 0.21 11.7 0.1 2.5 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain PDDEXK_1 PF12705.7 CDS26055.1 - 2.6e-05 24.3 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2075 PF09848.9 CDS26055.1 - 0.00023 20.5 0.0 0.00089 18.6 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CDS26055.1 - 0.008 16.5 0.6 0.18 12.1 0.1 3.3 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CDS26055.1 - 0.055 12.7 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin UvrD-helicase PF00580.21 CDS26055.1 - 0.069 12.6 0.0 1.5 8.3 0.0 2.2 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain mCpol PF18182.1 CDS26055.1 - 0.096 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain AAA_16 PF13191.6 CDS26055.1 - 0.13 12.7 0.5 2.2 8.6 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain Sec63 PF02889.16 CDS26056.1 - 2.1e-116 387.6 0.0 4.4e-63 212.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDS26056.1 - 1.6e-49 168.1 2.4 1.4e-23 83.5 0.0 3.3 4 0 0 4 4 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CDS26056.1 - 5.5e-26 91.6 0.0 9.4e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS26056.1 - 1.7e-16 60.5 0.0 2.2e-07 31.2 0.0 3.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 CDS26056.1 - 7.5e-10 38.8 0.5 0.00022 21.0 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDS26056.1 - 3.3e-09 37.2 0.3 0.0019 18.6 0.2 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CDS26056.1 - 7.9e-05 23.0 3.4 0.52 10.6 0.3 4.3 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 CDS26056.1 - 8.3e-05 23.0 0.4 1.4 9.4 0.4 3.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDS26056.1 - 0.00069 18.8 0.0 0.93 8.5 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 CDS26056.1 - 0.005 16.3 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 CDS26056.1 - 0.011 15.3 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TniB PF05621.11 CDS26056.1 - 0.014 14.8 0.3 2.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 CDS26056.1 - 0.021 14.4 0.1 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 CDS26056.1 - 0.052 13.9 0.1 12 6.3 0.0 3.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 CDS26056.1 - 0.13 11.5 0.0 3.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_11 PF13086.6 CDS26056.1 - 0.16 11.7 0.1 5 6.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain Helicase_PWI PF18149.1 CDS26057.1 - 0.00098 19.3 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain RasGEF PF00617.19 CDS26059.2 - 2.6e-46 158.0 0.0 5.3e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDS26059.2 - 1.9e-25 89.1 0.0 4.1e-11 43.1 0.0 2.9 2 0 0 2 2 2 2 RasGEF N-terminal motif cNMP_binding PF00027.29 CDS26059.2 - 1.9e-16 59.9 0.0 0.00039 20.4 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PDZ_6 PF17820.1 CDS26059.2 - 0.0069 16.2 0.1 0.023 14.5 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Cupin_3 PF05899.12 CDS26059.2 - 0.1 12.3 0.0 29 4.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Not1 PF04054.15 CDS26060.1 - 1.5e-35 122.8 0.5 1.5e-35 122.8 0.5 3.3 3 1 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CDS26060.1 - 2.6e-28 99.0 1.0 1.4e-27 96.6 0.1 2.7 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Not1 PF04054.15 CDS26061.2 - 5.7e-77 259.1 6.3 3.6e-44 151.2 0.0 3.0 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CDS26061.2 - 2.6e-57 193.8 1.4 3e-57 193.6 0.0 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CDS26061.2 - 5.2e-26 91.3 1.3 5.2e-26 91.3 1.3 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CDS26061.2 - 4.5e-17 61.8 0.0 4.5e-17 61.8 0.0 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Not1 PF04054.15 CDS26063.1 - 4e-21 75.4 1.2 3.1e-20 72.4 1.0 2.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CDS26063.1 - 6.5e-18 64.9 3.3 6.1e-10 38.9 1.3 3.3 2 1 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Mito_carr PF00153.27 CDS26064.1 - 7.7e-59 195.6 2.2 3.3e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SBF2 PF12335.8 CDS26065.1 - 1.2e-06 28.4 2.7 1.3e-06 28.2 1.1 1.8 2 0 0 2 2 2 1 Myotubularin protein 7tm_1 PF00001.21 CDS26066.1 - 1.5e-23 83.4 4.4 2.2e-12 46.9 0.0 2.6 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS26066.1 - 0.00029 20.3 2.3 0.00029 20.3 2.3 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4131 PF13567.6 CDS26066.1 - 0.072 12.7 0.7 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4307 PF14155.6 CDS26066.1 - 0.15 11.9 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Mt_ATP-synt_B PF05405.14 CDS26067.1 - 1.8e-33 115.5 0.5 1.8e-33 115.5 0.5 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sec34 PF04136.15 CDS26067.1 - 0.034 14.0 2.0 0.041 13.8 0.3 1.9 2 0 0 2 2 2 0 Sec34-like family BT1 PF03092.16 CDS26067.1 - 0.085 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 BT1 family V-ATPase_G_2 PF16999.5 CDS26067.1 - 0.87 10.0 7.5 1.1 9.8 3.4 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Syja_N PF02383.18 CDS26068.1 - 8e-84 281.7 0.0 1.1e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain PP2C PF00481.21 CDS26069.1 - 3.2e-62 210.5 0.1 4.3e-47 160.9 0.3 2.7 2 0 0 2 2 2 2 Protein phosphatase 2C PDZ PF00595.24 CDS26070.1 - 2.6e-118 386.6 10.4 4.2e-14 52.7 0.2 12.8 13 0 0 13 13 13 12 PDZ domain PDZ_6 PF17820.1 CDS26070.1 - 4.5e-79 260.2 14.0 1.9e-08 34.0 0.5 12.6 12 0 0 12 12 12 12 PDZ domain PDZ_2 PF13180.6 CDS26070.1 - 3.1e-49 165.2 7.2 4.1e-07 30.2 0.0 12.5 12 0 0 12 12 12 11 PDZ domain GRASP55_65 PF04495.14 CDS26070.1 - 4.6e-11 43.2 0.0 0.17 12.2 0.0 6.2 6 0 0 6 6 6 2 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 CDS26070.1 - 0.048 14.1 0.0 32 4.9 0.0 5.0 6 0 0 6 6 6 0 PDZ domain P4Ha_N PF08336.11 CDS26074.2 - 2.4 8.2 9.4 2 8.4 4.7 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Brr6_like_C_C PF10104.9 CDS26074.2 - 6.1 6.6 8.6 12 5.6 3.2 2.4 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain NDUFB10 PF10249.9 CDS26075.1 - 1.5e-45 154.8 8.6 2e-45 154.3 8.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Exo_endo_phos_2 PF14529.6 CDS26076.1 - 4e-10 39.6 0.1 6.4e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase FixO PF02433.15 CDS26076.1 - 0.033 13.6 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Exo_endo_phos PF03372.23 CDS26076.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.2 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family EAP30 PF04157.16 CDS26077.1 - 2.7e-35 121.8 0.4 6.9e-35 120.4 0.3 1.6 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CDS26077.1 - 4.9e-11 42.7 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 CDS26077.1 - 0.042 14.2 0.1 0.092 13.1 0.1 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Amino_oxidase PF01593.24 CDS26079.1 - 2.4e-76 257.9 0.1 2.9e-51 175.2 0.1 2.9 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDS26079.1 - 1.3e-10 41.3 0.5 3.1e-10 40.1 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDS26079.1 - 2.5e-06 26.5 0.8 3.6e-06 25.9 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CDS26079.1 - 4.9e-05 23.1 1.1 9.5e-05 22.1 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDS26079.1 - 6.3e-05 22.4 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDS26079.1 - 0.00016 22.2 0.2 0.00036 21.0 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDS26079.1 - 0.00027 20.3 0.6 0.0006 19.1 0.4 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CDS26079.1 - 0.00044 19.4 0.5 0.00072 18.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 CDS26079.1 - 0.00089 18.6 0.3 0.0017 17.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CDS26079.1 - 0.0012 18.2 0.3 0.0021 17.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDS26079.1 - 0.0017 17.8 1.6 0.0029 17.0 1.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDS26079.1 - 0.018 14.1 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein YjeF_N PF03853.15 CDS26079.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 CDS26079.1 - 0.076 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDS26079.1 - 0.22 10.6 0.9 0.36 9.9 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A KIAA1328 PF15369.6 CDS26079.1 - 4 7.2 8.9 0.52 10.1 3.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 CBFD_NFYB_HMF PF00808.23 CDS26081.1 - 2.1e-12 47.1 0.1 3.4e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS26081.1 - 8.5e-06 26.2 0.1 1.3e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS26081.1 - 0.00032 20.8 0.1 0.00077 19.6 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CDS26081.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UCH PF00443.29 CDS26082.1 - 1.4e-36 126.4 0.0 1.9e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CDS26082.1 - 1e-15 57.2 4.8 1.4e-10 40.9 0.4 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 CDS26082.1 - 1.7e-15 57.1 0.0 5.1e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDS26082.1 - 3.7e-10 39.9 0.0 5.2e-07 29.6 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 CDS26082.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain Tmpp129 PF10272.9 CDS26084.1 - 2e-75 254.3 0.0 2.4e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor RhodobacterPufX PF11511.8 CDS26086.1 - 0.017 14.7 1.1 0.41 10.3 0.1 2.5 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF2153 PF09921.9 CDS26086.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Dynactin_p22 PF07426.11 CDS26086.1 - 0.14 12.0 6.0 0.22 11.4 6.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Amnionless PF14828.6 CDS26086.1 - 0.19 10.5 1.0 7.1 5.3 0.0 2.3 2 0 0 2 2 2 0 Amnionless T2SSF PF00482.23 CDS26086.1 - 0.55 10.2 0.0 0.55 10.2 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Chromate_transp PF02417.15 CDS26086.1 - 1.4 9.1 11.4 0.4 10.8 4.6 2.5 2 0 0 2 2 2 0 Chromate transporter Phage_holin_3_6 PF07332.11 CDS26086.1 - 3.6 7.7 10.4 5.1 7.2 5.9 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF485 PF04341.12 CDS26086.1 - 4.4 7.3 14.1 1.5 8.8 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 zf-met PF12874.7 CDS26088.2 - 6.1e-07 29.6 6.3 0.0025 18.1 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDS26088.2 - 2.4e-06 27.7 7.7 0.00016 21.9 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26088.2 - 4e-06 27.0 0.8 4e-06 27.0 0.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26088.2 - 0.0016 19.1 0.8 0.0016 19.1 0.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS26088.2 - 0.016 15.5 0.0 0.016 15.5 0.0 2.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Retrotran_gag_2 PF14223.6 CDS26088.2 - 0.029 14.0 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_6 PF13912.6 CDS26088.2 - 0.037 14.0 1.2 0.037 14.0 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 CDS26088.2 - 0.15 12.1 7.4 0.18 11.8 1.0 2.8 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 CDS26088.2 - 0.23 11.8 2.9 0.84 10.0 3.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ras PF00071.22 CDS26090.1 - 2.7e-57 192.9 0.4 3.1e-57 192.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS26090.1 - 2.1e-20 73.1 0.0 3.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS26090.1 - 6e-10 38.8 0.1 7.2e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS26090.1 - 9e-07 28.6 1.2 3.1e-06 26.9 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS26090.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS26090.1 - 4.9e-05 23.3 1.5 0.17 11.7 0.1 2.6 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 CDS26090.1 - 0.003 17.0 0.1 0.0035 16.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDS26090.1 - 0.0034 16.9 0.4 0.033 13.7 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CDS26090.1 - 0.006 16.4 1.2 0.1 12.4 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CDS26090.1 - 0.0074 15.3 0.5 0.21 10.5 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ParA PF10609.9 CDS26090.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDS26090.1 - 0.062 13.4 0.3 0.17 11.9 0.3 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 CDS26090.1 - 0.084 12.4 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ldh_1_N PF00056.23 CDS26090.1 - 0.13 12.3 0.2 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Exo_endo_phos_2 PF14529.6 CDS26091.1 - 1.9e-16 60.0 0.2 3.7e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26091.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DIRP PF06584.13 CDS26092.1 - 9.2e-37 125.5 0.6 2e-36 124.4 0.6 1.6 1 0 0 1 1 1 1 DIRP RFX_DNA_binding PF02257.15 CDS26092.1 - 0.0054 17.3 0.4 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain DUF3861 PF12977.7 CDS26092.1 - 0.054 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) RNase_H PF00075.24 CDS26093.1 - 3.3e-34 118.1 0.0 5.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 RNase H PGM_PMM_I PF02878.16 CDS26093.1 - 4.2e-32 110.8 0.3 2.5e-31 108.2 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CDS26093.1 - 2.4e-25 88.9 0.0 4.5e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4517 PF15006.6 CDS26093.1 - 1.2e-22 80.7 0.0 2.1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4517) Cauli_VI PF01693.16 CDS26093.1 - 1.3e-17 63.8 0.5 3.3e-17 62.5 0.5 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin PGM_PMM_II PF02879.16 CDS26093.1 - 5e-14 52.8 0.0 1.3e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RVT_3 PF13456.6 CDS26093.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like PGM_PMM_IV PF00408.20 CDS26093.1 - 0.025 14.7 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1529 PF07485.11 CDS26093.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) Tropomyosin PF00261.20 CDS26094.1 - 8.3e-18 64.6 47.8 9.5e-18 64.4 47.8 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CDS26094.1 - 1.8e-06 28.2 48.4 7.4e-06 26.2 20.2 3.3 1 1 2 3 3 3 2 Tropomyosin like T3SSipB PF16535.5 CDS26094.1 - 0.13 12.8 26.4 1 9.8 6.6 3.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF1759 PF03564.15 CDS26094.1 - 0.14 12.1 11.5 0.1 12.6 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Fez1 PF06818.15 CDS26094.1 - 0.19 12.2 37.8 0.14 12.6 5.8 2.5 1 1 1 2 2 2 0 Fez1 CALCOCO1 PF07888.11 CDS26094.1 - 0.19 10.5 36.3 0.26 10.1 36.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 CDS26094.1 - 0.29 9.5 39.5 0.64 8.3 5.5 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Zwint PF15556.6 CDS26094.1 - 0.31 10.5 28.6 1.7 8.1 5.1 2.2 1 1 1 2 2 2 0 ZW10 interactor DUF3533 PF12051.8 CDS26094.1 - 0.36 9.7 2.2 0.49 9.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HOOK PF05622.12 CDS26094.1 - 1.3 7.0 39.8 0.27 9.3 18.8 3.1 1 1 2 3 3 3 0 HOOK protein HrpF PF06266.12 CDS26094.1 - 2.2 8.6 6.7 4.3 7.7 0.3 3.1 2 1 0 3 3 3 0 HrpF protein ERM PF00769.19 CDS26094.1 - 3 7.6 44.2 0.066 13.0 23.0 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family HisKA_3 PF07730.13 CDS26094.1 - 4.6 7.8 13.2 1e+02 3.5 0.3 4.4 3 1 0 3 3 3 0 Histidine kinase DUF87 PF01935.17 CDS26094.1 - 4.7 7.2 19.9 0.69 10.0 10.3 2.1 1 1 1 2 2 2 0 Helicase HerA, central domain DUF745 PF05335.13 CDS26094.1 - 5.9 6.6 29.4 0.31 10.7 3.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) zf-C2H2 PF00096.26 CDS26095.1 - 4.4e-07 30.0 41.3 0.00017 21.8 1.6 7.1 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDS26095.1 - 7.3e-07 29.4 21.4 4.6e-06 26.8 0.2 4.2 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CDS26095.1 - 0.00018 21.7 13.3 0.038 14.3 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CDS26095.1 - 0.00036 20.7 15.1 0.0046 17.2 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDS26095.1 - 0.00052 20.6 51.7 0.016 16.0 0.6 7.4 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2HE PF16278.5 CDS26095.1 - 0.00082 19.8 4.7 0.12 12.9 0.2 3.8 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CDS26095.1 - 0.0012 19.2 28.4 0.026 14.9 0.4 5.6 5 0 0 5 5 5 3 Zinc-finger double domain Plasmod_dom_1 PF09715.10 CDS26095.1 - 0.0071 16.4 0.1 0.024 14.7 0.1 1.9 1 0 0 1 1 1 1 Plasmodium protein of unknown function (Plasmod_dom_1) zf-C2H2_2 PF12756.7 CDS26095.1 - 0.0087 16.4 19.2 0.013 15.8 1.3 4.6 3 3 2 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 CDS26095.1 - 0.016 15.0 10.3 1.1 9.1 1.2 3.3 2 0 0 2 2 2 0 Zinc knuckle Elf1 PF05129.13 CDS26095.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.6 4 2 1 5 5 5 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 CDS26095.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.7 5 0 0 5 5 3 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 CDS26095.1 - 0.29 11.0 3.6 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CDS26095.1 - 0.38 11.2 20.8 0.2 12.1 0.9 5.3 6 0 0 6 6 5 0 Zinc-finger of C2H2 type CpXC PF14353.6 CDS26095.1 - 1.6 8.8 6.7 25 5.0 0.1 3.9 3 1 1 4 4 4 0 CpXC protein zf-TAZ PF02135.16 CDS26095.1 - 3.5 8.2 14.9 12 6.4 0.0 4.0 4 0 0 4 4 4 0 TAZ zinc finger Transposase_1 PF01359.18 CDS26096.1 - 8.2e-08 32.0 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_24 PF13412.6 CDS26096.1 - 0.00014 21.4 0.2 0.00025 20.5 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 CDS26096.1 - 0.015 15.4 0.2 0.041 13.9 0.2 1.8 1 1 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 CDS26096.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 CDS26096.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 CDS26096.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 CDS26096.1 - 0.098 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 CDS26096.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 CDS26096.1 - 0.16 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Cytochrom_B559a PF00284.20 CDS26096.1 - 0.22 11.3 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit DUF1604 PF07713.13 CDS26097.1 - 3.7e-32 110.0 3.1 9.6e-32 108.7 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) FAM221 PF14753.6 CDS26098.1 - 6.9e-83 277.1 4.8 8.3e-83 276.8 4.8 1.0 1 0 0 1 1 1 1 Protein FAM221A/B RRM_1 PF00076.22 CDS26099.1 - 1.4e-19 69.6 0.0 2.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.11 CDS26100.1 - 6.6e-19 67.5 2.0 1.4e-18 66.5 2.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Meis_PKNOX_N PF16493.5 CDS26100.1 - 4.6e-18 65.3 0.3 1.2e-17 64.0 0.2 1.7 2 0 0 2 2 2 1 N-terminal of Homeobox Meis and PKNOX1 Homeodomain PF00046.29 CDS26100.1 - 1.8e-07 30.9 1.1 3.9e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Homeodomain FYVE PF01363.21 CDS26101.1 - 3e-19 68.9 13.4 8.3e-19 67.5 13.4 1.8 1 0 0 1 1 1 1 FYVE zinc finger Med21 PF11221.8 CDS26101.1 - 0.0048 17.2 7.9 0.0048 17.2 7.9 5.9 3 2 3 6 6 5 1 Subunit 21 of Mediator complex ATG16 PF08614.11 CDS26101.1 - 0.0059 16.9 23.1 0.0059 16.9 23.1 4.9 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Elf1 PF05129.13 CDS26101.1 - 0.0071 16.4 4.4 0.041 13.9 4.4 2.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like TPR_MLP1_2 PF07926.12 CDS26101.1 - 0.0081 16.2 83.8 0.016 15.2 15.2 7.4 2 1 3 5 5 5 3 TPR/MLP1/MLP2-like protein Filament PF00038.21 CDS26101.1 - 0.012 15.2 67.9 0.52 9.8 4.2 5.0 2 1 1 3 3 3 0 Intermediate filament protein JIP_LZII PF16471.5 CDS26101.1 - 0.022 14.9 3.9 0.022 14.9 3.9 7.9 4 4 3 7 7 6 0 JNK-interacting protein leucine zipper II AAA_13 PF13166.6 CDS26101.1 - 0.024 13.3 67.8 0.021 13.5 20.0 3.7 1 1 2 4 4 4 0 AAA domain IBR PF01485.21 CDS26101.1 - 0.053 13.8 6.1 0.21 11.8 6.1 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4428 PF14471.6 CDS26101.1 - 0.057 13.3 6.8 1.6 8.7 0.0 4.2 3 1 1 4 4 3 0 Domain of unknown function (DUF4428) ADIP PF11559.8 CDS26101.1 - 0.097 12.8 75.9 0.12 12.4 9.3 6.6 2 1 4 6 6 5 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 CDS26101.1 - 0.18 12.2 0.1 0.18 12.2 0.1 8.0 7 1 0 7 7 5 0 Lipoprotein leucine-zipper Fez1 PF06818.15 CDS26101.1 - 0.7 10.3 69.3 0.46 10.9 2.4 4.7 2 1 3 5 5 5 0 Fez1 MAD PF05557.13 CDS26101.1 - 2.1 6.6 76.7 0.54 8.6 4.8 4.1 2 1 1 3 3 3 0 Mitotic checkpoint protein GATA PF00320.27 CDS26101.1 - 2.3 7.9 7.4 9.4 5.9 7.4 2.1 1 0 0 1 1 1 0 GATA zinc finger RPW8 PF05659.11 CDS26101.1 - 2.4 7.8 36.5 2.6 7.7 0.2 6.1 3 2 3 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4200 PF13863.6 CDS26101.1 - 2.9 8.3 68.5 0.12 12.8 10.1 5.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 CDS26101.1 - 3.6 6.4 88.1 0.099 11.5 18.3 4.5 2 1 2 4 4 4 0 Spc7 kinetochore protein GAS PF13851.6 CDS26101.1 - 6.8 6.0 85.8 0.048 13.0 18.9 5.7 2 1 3 6 6 6 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CDS26101.1 - 8.1 6.5 92.2 0.021 14.8 8.1 8.1 2 2 5 7 7 6 0 TATA element modulatory factor 1 DNA binding SNF2_N PF00176.23 CDS26103.1 - 1.2e-48 165.6 0.0 4.4e-33 114.5 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS26103.1 - 3.2e-15 56.4 0.0 4.7e-14 52.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS26103.1 - 1.2e-05 25.4 0.3 0.059 13.4 0.0 3.4 4 1 0 4 4 4 2 Type III restriction enzyme, res subunit AT_hook PF02178.19 CDS26103.1 - 1.6 8.9 3.5 5.1 7.3 3.5 1.9 1 0 0 1 1 1 0 AT hook motif COesterase PF00135.28 CDS26104.1 - 2e-142 475.7 0.0 2.3e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS26104.1 - 2e-07 31.1 0.0 8e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold SH2 PF00017.24 CDS26105.1 - 8.7e-11 41.8 0.1 2e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 CDS26105.1 - 4.1e-07 30.3 0.4 4.1e-07 30.3 0.4 2.6 3 0 0 3 3 3 1 SOCS box SH2_2 PF14633.6 CDS26105.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 SH2 domain Macoilin PF09726.9 CDS26105.1 - 8.4 4.8 6.1 13 4.2 6.1 1.2 1 0 0 1 1 1 0 Macoilin family IP_trans PF02121.18 CDS26106.1 - 1.2e-49 169.2 0.1 1.3e-49 169.0 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF3694 PF12473.8 CDS26109.1 - 2.3e-21 77.1 0.0 8.7e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 Kinesin protein bZIP_1 PF00170.21 CDS26111.2 - 0.1 12.7 0.3 0.16 12.1 0.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor DIL PF01843.19 CDS26113.1 - 0.0013 19.0 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 DIL domain RhoGEF PF00621.20 CDS26114.2 - 7.7e-27 94.7 0.3 1.9e-26 93.4 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.7 CDS26114.2 - 1.7e-11 43.9 0.4 1.2e-08 34.7 0.1 2.7 2 0 0 2 2 2 2 twin BRCT domain RVT_1 PF00078.27 CDS26114.2 - 9.2e-09 35.1 0.1 2.1e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BRCT PF00533.26 CDS26114.2 - 3.9e-07 30.4 0.0 0.016 15.6 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDS26114.2 - 0.0031 17.9 0.0 1 9.8 0.0 3.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Exo_endo_phos_2 PF14529.6 CDS26115.1 - 5.7e-09 35.8 0.2 8.3e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26115.1 - 0.00078 19.0 0.1 0.011 15.2 0.1 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MORN PF02493.20 CDS26116.1 - 8.9e-27 91.4 35.9 2.5e-05 23.9 1.3 8.0 7 0 0 7 7 7 7 MORN repeat PmbA_TldD PF01523.16 CDS26116.1 - 0.02 14.7 2.8 0.043 13.7 0.4 2.2 2 0 0 2 2 2 0 Putative modulator of DNA gyrase YtxH PF12732.7 CDS26116.1 - 0.62 10.6 5.6 2.8 8.5 5.0 2.4 2 0 0 2 2 2 0 YtxH-like protein Proteasome PF00227.26 CDS26117.1 - 1.6e-37 128.9 0.0 1.8e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.17 CDS26117.1 - 0.049 14.0 0.1 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Uteroglobin family COG4 PF08318.12 CDS26118.1 - 1.5e-67 228.0 5.9 1.5e-67 228.0 5.9 1.9 2 0 0 2 2 2 1 COG4 transport protein Sec10 PF07393.11 CDS26118.1 - 2.8e-05 22.8 0.2 6.5e-05 21.6 0.2 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec10 Skp1 PF01466.19 CDS26118.1 - 0.018 15.1 0.1 7.7 6.7 0.0 4.3 5 0 0 5 5 5 0 Skp1 family, dimerisation domain TPT PF03151.16 CDS26119.1 - 1.2e-06 28.1 0.4 1.4e-06 27.9 0.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family RRM_1 PF00076.22 CDS26120.1 - 3.4e-16 58.8 0.0 4.1e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS26120.1 - 2e-06 27.4 0.0 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS26120.1 - 2.9e-05 23.8 0.1 0.0073 16.1 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif WD40 PF00400.32 CDS26121.1 - 3.9e-44 147.8 10.8 2.2e-10 40.9 0.6 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 CDS26121.1 - 9.7e-41 139.5 0.4 1.8e-40 138.6 0.4 1.4 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 CDS26121.1 - 1.7e-17 63.5 0.0 1.8e-06 28.2 0.0 5.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS26121.1 - 7.4e-07 29.2 0.0 0.0026 17.7 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDS26121.1 - 4.5e-05 22.6 0.7 1.5 7.7 0.0 4.0 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDS26121.1 - 0.00019 20.2 0.0 13 4.3 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDS26121.1 - 0.00057 19.3 0.0 0.025 13.9 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 CDS26121.1 - 0.0069 15.0 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Ribosomal_S19e PF01090.19 CDS26122.1 - 4.3e-48 162.5 0.0 4.8e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_CodY PF08222.11 CDS26122.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_12 PF08461.10 CDS26122.1 - 0.13 12.2 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain STAG PF08514.11 CDS26123.1 - 3.7e-35 120.2 0.1 1.1e-34 118.8 0.1 1.8 1 0 0 1 1 1 1 STAG domain fn3 PF00041.21 CDS26124.2 - 3.5e-61 203.5 11.6 1.8e-07 31.4 0.1 14.7 12 2 1 13 13 13 10 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDS26124.2 - 3.3e-23 82.0 15.8 0.028 15.0 0.0 10.1 9 1 0 9 9 9 6 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CDS26124.2 - 0.0027 18.0 0.0 18 5.8 0.0 5.1 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 CDS26124.2 - 0.012 16.1 0.4 8.4 7.0 0.0 4.6 4 0 0 4 4 4 0 PhoD-like phosphatase, N-terminal domain ComX PF05952.12 CDS26124.2 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX Cg6151-P PF10233.9 CDS26125.1 - 3.8e-08 33.6 16.8 5.5e-08 33.1 16.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM43 PF07787.12 CDS26125.1 - 2.5 7.4 8.3 3.8 6.8 8.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 MRP-63 PF14978.6 CDS26126.1 - 3.8e-22 78.7 0.1 6.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 EF-hand_5 PF13202.6 CDS26127.1 - 4.6e-16 57.5 1.8 2e-07 30.2 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS26127.1 - 1e-13 51.5 0.4 9e-06 26.1 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS26127.1 - 1.7e-13 49.0 0.5 1.5e-05 24.2 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS26127.1 - 3.3e-13 48.4 0.6 1.5e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS26127.1 - 3.8e-10 39.5 1.1 6.5e-06 25.9 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS26127.1 - 0.00056 20.2 0.0 0.00083 19.7 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS26127.1 - 0.0087 16.4 0.0 0.1 12.9 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain CsgF PF10614.9 CDS26127.1 - 0.018 15.3 0.3 0.02 15.1 0.3 1.1 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein DUF4752 PF15944.5 CDS26127.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4752) Folliculin PF11704.8 CDS26128.1 - 1.4e-43 148.9 0.0 2.8e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Folliculin_C PF16692.5 CDS26128.1 - 2.3e-30 106.0 0.1 3.5e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Folliculin C-terminal domain Arm PF00514.23 CDS26129.1 - 4.9e-84 274.1 15.9 1e-12 47.6 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CDS26129.1 - 5.5e-23 79.1 1.1 0.0012 18.9 0.0 7.3 7 0 0 7 7 6 4 HEAT repeat HEAT_EZ PF13513.6 CDS26129.1 - 2.6e-22 78.9 4.9 2.4e-08 34.3 0.1 6.5 7 1 1 8 8 7 4 HEAT-like repeat HEAT_2 PF13646.6 CDS26129.1 - 1.2e-20 73.6 0.0 2.1e-05 24.8 0.0 5.7 2 2 2 4 4 4 4 HEAT repeats IBB PF01749.20 CDS26129.1 - 7.1e-16 58.4 0.7 1.5e-14 54.2 0.6 2.6 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 CDS26129.1 - 4.2e-13 48.6 0.0 4.2e-10 39.0 0.1 2.6 2 0 0 2 2 2 2 Atypical Arm repeat Adaptin_N PF01602.20 CDS26129.1 - 7.1e-12 44.7 0.0 1.4e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDS26129.1 - 1.3e-07 31.8 0.1 0.16 12.0 0.0 3.8 1 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Mo25 PF08569.11 CDS26129.1 - 1.5e-07 31.1 0.0 6.3e-06 25.8 0.1 2.3 1 1 1 2 2 2 1 Mo25-like V-ATPase_H_C PF11698.8 CDS26129.1 - 5.9e-07 29.6 0.1 0.94 9.6 0.0 4.6 2 1 2 5 5 5 3 V-ATPase subunit H Arm_2 PF04826.13 CDS26129.1 - 0.00028 20.4 3.1 1.7 8.1 0.7 3.9 2 1 2 4 4 4 1 Armadillo-like ParcG PF10274.9 CDS26129.1 - 0.00036 20.7 1.2 0.018 15.2 0.1 3.0 2 1 0 3 3 3 1 Parkin co-regulated protein HEAT_PBS PF03130.16 CDS26129.1 - 0.00055 20.4 0.2 31 5.6 0.0 5.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CDS26129.1 - 0.00072 19.5 0.7 3.8 7.6 0.1 3.6 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain DRIM PF07539.12 CDS26129.1 - 0.012 14.0 1.0 2.6 6.3 0.1 2.6 1 1 2 3 3 3 0 Down-regulated in metastasis CTNNBL PF08216.11 CDS26129.1 - 0.16 12.2 1.6 2.6 8.3 0.1 3.7 6 0 0 6 6 5 0 Catenin-beta-like, Arm-motif containing nuclear IFRD PF05004.13 CDS26129.1 - 0.16 11.0 0.6 41 3.1 0.0 3.7 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) DUF3361 PF11841.8 CDS26129.1 - 0.21 11.5 3.9 9.6 6.1 0.1 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF3361) SAPS PF04499.15 CDS26129.1 - 2.4 6.8 5.1 3.9 6.2 0.5 3.0 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein Mito_carr PF00153.27 CDS26130.1 - 1.7e-58 194.5 1.9 2.2e-19 69.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CDS26131.1 - 5.7e-07 29.2 0.5 4e-05 23.1 0.2 2.3 1 1 1 2 2 2 2 Protein kinase domain D123 PF07065.14 CDS26131.1 - 0.039 13.1 0.4 0.064 12.4 0.4 1.2 1 0 0 1 1 1 0 D123 Myosin_head PF00063.21 CDS26132.2 - 1e-291 969.2 2.3 4.4e-291 967.1 2.3 2.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDS26132.2 - 4e-236 786.5 285.4 5e-236 786.2 285.4 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDS26132.2 - 1.6e-11 43.9 0.2 3.9e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CDS26132.2 - 0.051 13.8 0.0 0.051 13.8 0.0 6.2 4 1 3 7 7 7 0 AAA domain IQ PF00612.27 CDS26132.2 - 0.087 12.7 0.1 0.087 12.7 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Spore_SspJ PF09575.10 CDS26132.2 - 0.12 12.8 11.8 1.9 8.9 0.5 5.6 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) DUF3719 PF12516.8 CDS26133.1 - 8.5e-06 25.4 0.1 4.3e-05 23.1 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) Synaptobrevin PF00957.21 CDS26134.1 - 2.6e-30 104.1 2.7 2.6e-30 104.1 2.7 1.6 2 0 0 2 2 2 1 Synaptobrevin MCU PF04678.13 CDS26134.1 - 0.0063 16.6 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF4736 PF15883.5 CDS26134.1 - 0.45 10.2 2.8 1.4 8.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Transposase_1 PF01359.18 CDS26135.1 - 1.2e-22 79.5 0.0 1.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Transposase (partial DDE domain) FlaC_arch PF05377.11 CDS26138.1 - 0.00053 20.3 4.4 0.26 11.7 0.5 3.3 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Nup88 PF10168.9 CDS26138.1 - 0.0012 16.7 0.6 0.0014 16.5 0.6 1.1 1 0 0 1 1 1 1 Nuclear pore component ATG16 PF08614.11 CDS26138.1 - 0.0089 16.3 2.7 0.0089 16.3 2.7 2.7 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 CDS26138.1 - 0.035 14.4 1.9 0.49 10.7 2.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 JIP_LZII PF16471.5 CDS26138.1 - 0.064 13.4 6.0 0.97 9.7 0.7 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 CDS26138.1 - 0.092 12.8 1.2 4.8 7.2 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 CDS26138.1 - 0.13 12.2 6.6 0.48 10.4 0.8 2.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p bZIP_Maf PF03131.17 CDS26138.1 - 0.14 12.7 7.4 0.88 10.1 0.7 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor PspA_IM30 PF04012.12 CDS26138.1 - 0.16 11.5 4.7 1.8 8.1 5.2 2.1 1 1 0 1 1 1 0 PspA/IM30 family Uso1_p115_C PF04871.13 CDS26138.1 - 0.17 12.3 5.2 5 7.5 4.4 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 CDS26138.1 - 0.21 11.7 9.2 0.17 11.9 3.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 CDS26138.1 - 0.26 10.9 9.6 7.8 6.0 1.8 2.9 2 1 0 3 3 3 0 Intermediate filament protein ZapB PF06005.12 CDS26138.1 - 0.29 11.6 13.6 2.2 8.8 1.1 2.9 2 1 1 3 3 3 0 Cell division protein ZapB DUF4164 PF13747.6 CDS26138.1 - 0.36 11.1 10.2 0.31 11.3 3.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 CDS26138.1 - 0.81 10.2 12.8 0.57 10.7 3.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Cnn_1N PF07989.11 CDS26138.1 - 0.89 9.8 8.0 0.57 10.4 0.2 2.9 3 1 0 3 3 2 0 Centrosomin N-terminal motif 1 Fungal_TACC PF12709.7 CDS26138.1 - 0.99 9.9 5.1 7 7.2 0.3 2.4 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Golgin_A5 PF09787.9 CDS26138.1 - 1.4 8.3 9.5 2.1 7.7 2.6 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF5320 PF17253.2 CDS26138.1 - 2.3 9.3 7.2 63 4.7 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5320) HALZ PF02183.18 CDS26138.1 - 3 8.1 13.8 0.76 10.1 3.4 3.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper RAP1 PF07218.11 CDS26138.1 - 3.8 5.7 7.6 4.7 5.4 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4140 PF13600.6 CDS26138.1 - 6.3 7.3 7.2 15 6.1 0.4 2.6 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) KIAA1430 PF13879.6 CDS26138.1 - 6.8 7.5 12.3 0.38 11.5 5.2 2.5 2 1 1 3 3 3 0 KIAA1430 homologue Spc24 PF08286.11 CDS26138.1 - 8 6.8 12.6 1.3 9.3 3.1 2.6 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF945 PF06097.11 CDS26139.2 - 7e-05 22.1 0.0 0.3 10.2 0.0 4.3 2 2 1 3 3 3 2 Bacterial protein of unknown function (DUF945) THUMP PF02926.17 CDS26139.2 - 0.00011 22.3 1.0 42 4.2 0.0 5.2 6 0 0 6 6 6 3 THUMP domain DUF2993 PF11209.8 CDS26139.2 - 0.04 14.2 0.0 0.67 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2993) FAD_binding_7 PF03441.14 CDS26140.1 - 3e-74 248.9 0.5 4.4e-74 248.3 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CDS26140.1 - 9.1e-35 120.1 0.0 1.7e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Fmp27_GFWDK PF10347.9 CDS26140.1 - 0.089 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RhoGAP PF00620.27 CDS26141.1 - 5.4e-22 78.3 0.0 7.4e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain MyTH4 PF00784.17 CDS26141.1 - 3.6e-19 69.3 0.0 2e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 CDS26141.1 - 0.00013 22.0 6.5 0.047 13.8 5.8 2.6 2 0 0 2 2 2 2 WW domain UBD PF16455.5 CDS26142.1 - 3.2e-35 120.5 0.0 6.6e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 CDS26142.1 - 5.5e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Duffy_binding PF05424.11 CDS26142.1 - 0.076 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Duffy binding domain Galactosyl_T PF01762.21 CDS26143.1 - 3e-25 89.2 0.0 4.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Ras PF00071.22 CDS26144.1 - 0.00061 19.4 0.5 0.094 12.3 0.3 2.3 2 0 0 2 2 2 2 Ras family Sporozoite_P67 PF05642.11 CDS26144.1 - 0.054 11.6 0.6 0.11 10.6 0.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LEM PF03020.15 CDS26145.1 - 1.8e-07 30.6 0.1 2.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 LEM domain DUF2207 PF09972.9 CDS26145.1 - 0.28 9.9 2.6 0.11 11.3 0.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CCDC106 PF15794.5 CDS26145.1 - 1.5 8.5 9.0 2.4 7.8 9.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 CDS26145.1 - 1.7 7.1 8.8 2.1 6.8 8.8 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CDS26145.1 - 2.4 5.2 5.5 2.8 5.0 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 CDS26145.1 - 9.3 5.9 16.4 13 5.4 16.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Tom37 PF10568.9 CDS26146.1 - 5.7e-12 46.0 0.3 2.4e-11 44.0 0.2 1.9 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CDS26146.1 - 1.7e-09 38.3 0.0 3.8e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CDS26146.1 - 0.0054 16.5 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ANAPC4 PF12896.7 CDS26147.1 - 1.6e-19 70.2 2.9 2.3e-19 69.7 2.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CDS26147.1 - 2.1e-16 60.0 0.0 4.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_1b PF00579.25 CDS26148.1 - 1.7e-54 185.1 0.0 3.8e-54 184.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) DUF1657 PF07870.11 CDS26148.1 - 0.021 14.7 1.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) SNARE PF05739.19 CDS26148.1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 SNARE domain Syntaxin-18_N PF10496.9 CDS26148.1 - 0.043 14.1 0.4 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus HEPN_Swt1 PF18731.1 CDS26148.1 - 0.1 12.9 0.2 0.58 10.5 0.2 2.3 1 1 0 1 1 1 0 Swt1-like HEPN CAP_N PF01213.19 CDS26148.1 - 0.18 11.2 1.9 0.55 9.7 0.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Syntaxin-6_N PF09177.11 CDS26148.1 - 0.67 10.5 0.0 0.67 10.5 0.0 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 CDS26148.1 - 1.3 9.4 9.1 3.6 8.0 1.1 3.0 3 0 0 3 3 3 0 Syntaxin-like protein FH2 PF02181.23 CDS26148.1 - 5.7 6.0 8.5 0.73 8.9 0.2 2.7 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF4179 PF13786.6 CDS26149.1 - 0.073 13.6 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF969 PF06149.12 CDS26149.1 - 0.13 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF969) Ank_4 PF13637.6 CDS26151.1 - 1.1e-29 102.4 5.7 2.3e-09 37.6 0.0 5.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS26151.1 - 1.6e-29 102.3 2.1 1.6e-12 47.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS26151.1 - 2.1e-29 101.2 15.9 2.1e-08 34.3 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS26151.1 - 4.6e-23 80.6 10.6 0.00076 19.8 0.2 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CDS26151.1 - 4.2e-21 72.8 9.1 0.00055 20.2 0.1 6.0 5 0 0 5 5 5 5 Ankyrin repeat DUF1515 PF07439.11 CDS26151.1 - 5.9 7.0 5.5 3.4 7.8 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Pribosyltran PF00156.27 CDS26153.1 - 3.8e-18 65.5 0.1 5.2e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDS26153.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.5 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.25 CDS26155.1 - 2.7e-35 122.0 0.0 4.2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26155.1 - 5.6e-33 114.3 0.0 1.1e-32 113.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 CDS26155.1 - 2.9e-07 29.9 0.7 2.9e-07 29.9 0.7 2.3 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif APH PF01636.23 CDS26155.1 - 0.052 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS26155.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3377 PF11857.8 CDS26155.1 - 0.18 11.8 0.7 0.37 10.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4344 PF14247.6 CDS26156.2 - 0.1 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase LisH PF08513.11 CDS26156.2 - 0.13 12.3 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 LisH CRAL_TRIO PF00650.20 CDS26157.1 - 2.2e-10 40.5 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDS26157.1 - 0.019 15.1 0.1 0.062 13.5 0.0 1.9 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain RA PF00788.23 CDS26158.1 - 0.00019 22.0 0.1 0.00045 20.8 0.0 1.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain UPF0449 PF15136.6 CDS26158.1 - 4.5 7.8 7.2 0.3 11.6 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LRR_6 PF13516.6 CDS26162.1 - 6.2e-07 29.0 1.4 0.00051 19.9 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 CDS26162.1 - 0.013 16.0 2.8 7.2 7.6 0.6 3.2 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 CDS26162.1 - 0.056 13.9 2.3 0.89 10.1 0.2 2.8 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 CDS26163.1 - 0.00064 19.6 0.3 0.00086 19.2 0.3 1.1 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CDS26163.1 - 0.028 15.3 0.0 0.039 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.10 CDS26163.1 - 0.04 14.3 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF3377 PF11857.8 CDS26163.1 - 0.34 10.9 1.6 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CorA PF01544.18 CDS26164.1 - 0.72 9.1 3.0 1.2 8.3 3.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 CDS26165.1 - 2.1e-45 153.2 1.1 3.8e-13 49.8 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS26165.1 - 7.5e-30 102.9 5.5 1.2e-07 32.1 0.3 6.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CDS26165.1 - 2.6e-29 100.3 2.3 5.6e-05 23.4 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 CDS26165.1 - 6.6e-24 81.4 4.2 0.00049 20.3 0.0 7.8 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDS26165.1 - 8.7e-22 76.9 5.8 4.4e-05 23.7 0.4 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) PUL PF08324.11 CDS26165.1 - 0.2 10.9 0.2 0.59 9.3 0.0 1.8 2 0 0 2 2 2 0 PUL domain CYYR1 PF10873.8 CDS26166.1 - 0.049 14.1 1.4 0.06 13.8 1.0 1.4 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF2207 PF09972.9 CDS26166.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Arm PF00514.23 CDS26167.1 - 3.1e-18 65.1 17.3 0.00014 21.8 0.1 9.4 10 1 0 10 10 10 3 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 CDS26167.1 - 0.0001 21.7 3.2 0.034 13.4 0.9 3.1 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CDS26167.1 - 0.00062 20.1 2.7 0.073 13.5 0.2 4.3 4 1 1 5 5 5 1 HEAT repeats KAP PF05804.12 CDS26167.1 - 0.0035 15.6 1.0 0.0085 14.3 1.0 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Atx10homo_assoc PF09759.9 CDS26167.1 - 0.015 15.3 0.8 0.083 12.9 0.3 2.3 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm_3 PF16186.5 CDS26167.1 - 0.038 13.6 0.0 0.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Atypical Arm repeat GlnE PF03710.15 CDS26167.1 - 0.057 12.8 1.9 0.19 11.1 0.4 2.5 3 0 0 3 3 3 0 Glutamate-ammonia ligase adenylyltransferase RTTN_N PF14726.6 CDS26167.1 - 0.067 14.0 1.2 1.3 9.9 0.0 3.3 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning Thioredoxin_15 PF18403.1 CDS26167.1 - 0.08 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Arm_2 PF04826.13 CDS26167.1 - 0.092 12.2 5.0 1.2 8.5 0.1 3.4 3 1 2 5 5 5 0 Armadillo-like Membr_traf_MHD PF10540.9 CDS26168.2 - 1.6e-41 142.0 0.7 1.5e-40 138.8 0.0 2.8 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CDS26168.2 - 8e-37 125.7 0.0 2e-25 89.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF1041 PF06292.17 CDS26168.2 - 1.3e-29 102.7 0.5 4.3e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 CDS26168.2 - 5.6e-12 45.4 5.4 5.6e-12 45.4 5.4 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CEP76-C2 PF15627.6 CDS26168.2 - 0.00038 20.1 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain Otopetrin PF03189.13 CDS26169.1 - 3.5e-88 296.4 23.5 6.6e-60 203.2 8.7 2.2 1 1 1 2 2 2 2 Otopetrin Otopetrin PF03189.13 CDS26170.1 - 6.3e-85 285.6 15.6 1.9e-72 244.5 5.6 2.9 1 1 1 2 2 2 2 Otopetrin Pes-10 PF07149.11 CDS26170.1 - 0.042 12.9 4.4 0.065 12.3 4.4 1.2 1 0 0 1 1 1 0 Pes-10 Tetraspanin PF00335.20 CDS26170.1 - 0.067 12.9 3.7 7.9 6.1 0.0 3.4 3 0 0 3 3 3 0 Tetraspanin family Spo7 PF03907.13 CDS26170.1 - 0.57 9.6 6.4 7.3 6.0 1.6 2.7 2 0 0 2 2 2 0 Spo7-like protein DUF2951 PF11166.8 CDS26170.1 - 5.3 7.3 4.9 7.4 6.9 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Ldl_recept_a PF00057.18 CDS26171.2 - 0.015 15.5 2.8 0.048 13.9 2.8 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A YTH PF04146.15 CDS26172.1 - 7.6e-29 100.8 1.3 2.5e-19 69.8 0.1 3.4 3 0 0 3 3 3 2 YT521-B-like domain PH PF00169.29 CDS26173.1 - 0.0066 16.9 0.6 0.066 13.7 0.0 2.5 2 1 0 2 2 2 1 PH domain MORN PF02493.20 CDS26175.1 - 7.7e-31 104.1 49.7 2.2e-08 33.5 1.9 7.3 7 0 0 7 7 7 7 MORN repeat Pec_lyase_C PF00544.19 CDS26175.1 - 0.017 14.7 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Pectate lyase MFS_1 PF07690.16 CDS26176.2 - 4.3e-22 78.5 36.4 2.2e-18 66.3 3.4 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily PDZ PF00595.24 CDS26180.2 - 3.9e-06 27.1 0.0 8.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS26180.2 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Anthrax-tox_M PF09156.10 CDS26180.2 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Cytochrom_C1 PF02167.15 CDS26181.1 - 2.8e-89 298.6 0.0 3.4e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CDS26181.1 - 0.0028 17.9 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CDS26181.1 - 0.0039 18.3 0.1 0.012 16.7 0.1 1.9 1 0 0 1 1 1 1 Cytochrome c SUR7 PF06687.12 CDS26182.1 - 0.028 14.0 2.3 0.22 11.1 0.1 2.7 3 0 0 3 3 3 0 SUR7/PalI family Amastin PF07344.11 CDS26182.1 - 0.031 14.1 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein Orf78 PF06024.12 CDS26182.1 - 0.032 14.5 0.1 0.032 14.5 0.1 2.1 2 1 1 3 3 3 0 Orf78 (ac78) LtrA PF06772.11 CDS26182.1 - 0.045 13.0 1.8 1.2 8.3 0.0 2.6 2 1 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) DUF4118 PF13493.6 CDS26182.1 - 0.072 12.9 0.3 0.072 12.9 0.3 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4118) Tweety PF04906.13 CDS26182.1 - 0.28 9.8 1.1 0.55 8.8 1.1 1.4 1 0 0 1 1 1 0 Tweety Actin PF00022.19 CDS26183.1 - 6.6e-149 496.0 0.0 1.5e-148 494.8 0.0 1.5 1 1 0 1 1 1 1 Actin Ndr PF03096.14 CDS26184.1 - 3.4e-49 167.1 0.0 6e-30 103.9 0.0 3.0 2 1 0 2 2 2 2 Ndr family PAS_7 PF12860.7 CDS26184.1 - 0.14 12.3 0.0 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 PAS fold Exotox-A_cataly PF09009.10 CDS26184.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic IATP PF04568.12 CDS26185.1 - 1.3e-20 73.6 0.4 1.6e-20 73.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP RasGAP_C PF03836.15 CDS26185.1 - 0.02 15.0 1.4 0.027 14.6 1.4 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Kazal_2 PF07648.15 CDS26188.1 - 7.4e-15 54.8 14.8 4.5e-06 26.7 5.2 4.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CDS26188.1 - 4.7e-08 32.9 14.7 0.00055 19.9 0.0 4.3 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain Fig1 PF12351.8 CDS26188.1 - 0.079 12.9 0.4 0.079 12.9 0.4 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 LIM PF00412.22 CDS26190.1 - 4e-27 94.2 42.4 6.5e-11 42.3 4.1 3.8 3 1 0 3 3 3 3 LIM domain Ceramidse_alk_C PF17048.5 CDS26190.1 - 0.2 11.5 0.1 0.32 10.9 0.1 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal Mob1_phocein PF03637.17 CDS26191.2 - 1.7e-72 242.9 0.0 2.2e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Tmemb_14 PF03647.13 CDS26192.1 - 9.7e-22 77.5 9.2 1.1e-21 77.3 9.2 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Integrase_H2C2 PF17921.1 CDS26193.1 - 1.2e-09 38.1 2.0 2.4e-09 37.2 2.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDS26193.1 - 5.4e-07 29.8 0.4 1.6e-05 25.0 0.0 2.6 2 1 1 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 CDS26193.1 - 0.024 14.9 0.1 0.059 13.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Exo_endo_phos_2 PF14529.6 CDS26194.1 - 0.00018 21.4 0.7 0.00038 20.3 0.1 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase IRS PF02174.17 CDS26196.1 - 3.1e-09 36.6 0.0 6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Actin PF00022.19 CDS26198.1 - 1.8e-88 296.9 0.0 6.9e-50 169.8 0.0 3.0 1 1 2 3 3 3 3 Actin Actin PF00022.19 CDS26200.1 - 2.9e-147 490.5 0.0 1.1e-146 488.7 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CDS26200.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MreB_Mbl PF06723.13 CDS26200.1 - 0.21 10.4 0.0 1 8.1 0.0 2.1 2 1 0 2 2 2 0 MreB/Mbl protein Tcp11 PF05794.13 CDS26201.1 - 1.7e-93 314.2 0.1 2e-93 313.9 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 RGS_DHEX PF18148.1 CDS26201.1 - 0.13 12.4 0.0 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain UQ_con PF00179.26 CDS26202.1 - 1.9e-17 63.2 0.0 4.3e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Co_AT_N PF12557.8 CDS26202.1 - 3.8 7.5 5.2 11 6.1 5.2 1.8 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Transposase_1 PF01359.18 CDS26206.1 - 3.1e-09 36.5 0.1 4.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) zf-C2H2 PF00096.26 CDS26207.1 - 6.4e-21 73.6 55.9 0.00058 20.2 0.3 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26207.1 - 6.7e-13 48.4 55.1 5.5e-06 26.6 0.1 9.8 10 0 0 10 10 10 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26207.1 - 2.1e-11 43.6 51.3 0.024 15.4 0.2 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDS26207.1 - 4.5e-09 36.5 22.0 6.4e-05 23.2 4.1 4.2 4 0 0 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CDS26207.1 - 0.00015 21.7 23.9 0.47 10.5 0.1 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CDS26207.1 - 0.0033 17.6 25.0 0.91 9.6 0.2 5.4 3 2 1 4 4 4 2 Aberrant zinc-finger zf_ZIC PF18366.1 CDS26207.1 - 0.0043 17.1 13.7 1.8 8.8 0.0 5.7 5 1 1 6 6 6 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 CDS26207.1 - 0.025 14.9 12.3 4.1 7.8 0.4 6.1 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS26207.1 - 0.083 12.7 10.4 0.95 9.3 0.1 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type IBR PF01485.21 CDS26207.1 - 2.5 8.4 20.9 3.2 8.1 0.1 5.1 5 0 0 5 5 5 0 IBR domain, a half RING-finger domain DASH_Spc34 PF08657.10 CDS26209.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.5 2 0 0 2 2 2 1 DASH complex subunit Spc34 RhoGAP PF00620.27 CDS26211.1 - 3.2e-14 53.0 0.0 6.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CDS26211.1 - 1e-11 44.8 0.1 2.1e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 CDS26211.1 - 0.00015 21.5 0.1 0.00047 19.9 0.0 1.8 1 1 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Hepatitis_core PF00906.20 CDS26211.1 - 0.059 12.9 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Hepatitis core antigen RPN7 PF10602.9 CDS26212.1 - 2.1e-30 105.7 0.4 4e-30 104.8 0.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CDS26212.1 - 4.9e-11 43.1 0.0 1.3e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 CDS26212.1 - 0.067 13.2 0.1 0.66 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS26212.1 - 0.087 13.0 0.1 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BID PF06393.11 CDS26212.1 - 0.12 12.0 0.2 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) AA_permease_2 PF13520.6 CDS26213.1 - 9.3e-58 196.0 49.0 1.2e-57 195.7 49.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS26213.1 - 1.3e-21 76.8 46.5 2e-21 76.2 46.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDS26214.1 - 1.5e-53 182.1 52.5 2.1e-53 181.7 52.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS26214.1 - 3.3e-18 65.5 50.2 4.4e-18 65.1 49.9 1.4 1 1 0 1 1 1 1 Amino acid permease Pyrid_oxidase_2 PF13883.6 CDS26215.2 - 0.52 10.2 2.4 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase PIP49_C PF12260.8 CDS26217.1 - 3e-13 49.8 0.0 7.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DEK_C PF08766.11 CDS26217.1 - 4.4e-13 48.9 0.0 1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.27 CDS26217.1 - 3.4e-06 26.7 0.2 7.1e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 SAP domain Ntox22 PF15527.6 CDS26218.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 22 bZIP_2 PF07716.15 CDS26219.1 - 2.8e-22 78.5 34.1 4.5e-14 52.3 16.7 2.9 2 1 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 CDS26219.1 - 3.9e-06 26.9 29.5 0.0011 19.0 13.0 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 CDS26219.1 - 0.0013 19.2 6.2 0.0013 19.2 6.2 2.6 2 1 0 2 2 2 1 bZIP Maf transcription factor NRBF2 PF08961.10 CDS26219.1 - 0.0095 15.6 1.8 0.025 14.2 1.8 1.6 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 CDS26219.1 - 0.028 14.6 3.8 0.084 13.1 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 CDS26219.1 - 1.2 10.1 17.6 0.091 13.7 4.7 2.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 CDS26219.1 - 1.6 8.6 5.6 0.25 11.1 0.3 2.4 2 2 1 3 3 3 0 Septum formation initiator Axin_b-cat_bind PF08833.10 CDS26219.1 - 4.1 7.6 6.8 3.8 7.7 0.1 2.9 3 0 0 3 3 3 0 Axin beta-catenin binding domain Kinesin PF00225.23 CDS26220.1 - 5.8e-91 304.9 0.1 1.2e-90 303.9 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDS26220.1 - 5.4e-14 52.4 0.4 2.6e-13 50.2 0.1 2.1 2 0 0 2 2 2 1 Microtubule binding DUF4666 PF15697.5 CDS26220.1 - 0.11 13.2 0.3 0.11 13.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Serinc PF03348.15 CDS26221.1 - 2e-130 435.6 21.0 2.2e-130 435.4 21.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) UL2 PF08196.11 CDS26221.1 - 1.5 8.8 8.4 0.65 10.0 0.2 3.5 3 0 0 3 3 3 0 UL2 protein DUF4956 PF16316.5 CDS26221.1 - 2.9 7.5 11.3 3.5 7.3 5.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Serinc PF03348.15 CDS26222.1 - 1.4e-110 370.2 17.3 1.6e-110 370.0 17.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SBF PF01758.16 CDS26223.1 - 3.8e-08 33.2 7.1 3.8e-08 33.2 7.1 1.8 1 1 0 1 1 1 1 Sodium Bile acid symporter family Jas PF16135.5 CDS26223.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Galactosyl_T PF01762.21 CDS26225.1 - 2.2e-12 47.2 0.0 4.2e-12 46.3 0.0 1.4 2 0 0 2 2 2 1 Galactosyltransferase Nop PF01798.18 CDS26230.1 - 8.1e-76 254.5 0.0 2.1e-75 253.1 0.0 1.8 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF676 PF05057.14 CDS26230.1 - 3.8e-44 150.8 0.1 8.6e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) EF-hand_6 PF13405.6 CDS26230.1 - 1.1e-16 59.3 4.8 1.8e-06 27.4 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CDS26230.1 - 8.8e-16 58.1 9.5 1.4e-09 38.2 4.8 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS26230.1 - 8.3e-15 53.2 10.4 5.7e-08 31.8 0.2 4.6 4 0 0 4 4 4 3 EF hand RNase_PH PF01138.21 CDS26230.1 - 1.1e-14 55.1 0.0 1.1e-14 55.1 0.0 3.2 4 0 0 4 4 2 1 3' exoribonuclease family, domain 1 EF-hand_5 PF13202.6 CDS26230.1 - 5.1e-10 38.4 10.5 0.0003 20.1 0.8 4.7 4 0 0 4 4 4 2 EF hand NOP5NT PF08156.13 CDS26230.1 - 2.4e-09 37.5 0.4 7e-09 36.0 0.4 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Palm_thioest PF02089.15 CDS26230.1 - 1.2e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF3657 PF12394.8 CDS26230.1 - 5.3e-06 26.9 0.9 1.6e-05 25.4 0.1 2.3 2 0 0 2 2 1 1 Protein FAM135 EF-hand_8 PF13833.6 CDS26230.1 - 6.8e-05 22.6 6.0 0.00065 19.5 2.5 3.6 3 0 0 3 3 3 1 EF-hand domain pair PGAP1 PF07819.13 CDS26230.1 - 7.7e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TSP_1 PF00090.19 CDS26230.1 - 0.014 15.6 30.5 0.0098 16.1 15.1 3.6 2 1 0 2 2 2 0 Thrombospondin type 1 domain V-set PF07686.17 CDS26230.1 - 0.048 13.8 0.0 0.59 10.3 0.0 2.8 3 0 0 3 3 3 0 Immunoglobulin V-set domain LCAT PF02450.15 CDS26230.1 - 0.062 12.5 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SAT PF16073.5 CDS26231.1 - 0.018 14.8 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis CCDC53 PF10152.9 CDS26231.1 - 8.2 6.8 8.4 6.1 7.2 2.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Tubulin PF00091.25 CDS26232.1 - 2.3e-69 233.5 0.0 3.6e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS26232.1 - 3e-43 147.0 0.1 5e-43 146.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS26232.1 - 8.4e-06 26.1 0.0 2.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS26232.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS26232.1 - 0.0041 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Glycos_transf_3 PF00591.21 CDS26233.1 - 1.2e-31 110.3 0.2 1.7e-31 109.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 CDS26233.1 - 2.3e-20 72.0 0.1 5.7e-20 70.7 0.1 1.7 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 CDS26233.1 - 7.3e-17 61.0 0.0 1.7e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain LSM PF01423.22 CDS26234.1 - 3.7e-15 55.4 0.0 5.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain Ocnus PF05005.15 CDS26234.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Janus/Ocnus family (Ocnus) Ependymin PF00811.18 CDS26235.1 - 0.0081 16.4 39.6 3.5 7.9 0.4 10.2 4 4 7 11 11 11 7 Ependymin CDH-cyt PF16010.5 CDS26235.1 - 0.018 14.7 19.8 6.2 6.5 0.1 8.3 1 1 8 10 10 10 0 Cytochrome domain of cellobiose dehydrogenase HTH_7 PF02796.15 CDS26235.1 - 4.2 7.5 6.6 3e+02 1.6 0.0 5.0 5 0 0 5 5 5 0 Helix-turn-helix domain of resolvase Bestrophin PF01062.21 CDS26236.1 - 2.7e-84 283.1 7.1 3.1e-84 282.9 7.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel BPD_transp_1 PF00528.22 CDS26236.1 - 0.068 12.9 6.2 0.023 14.4 2.5 2.1 2 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component 7TM_GPCR_Srw PF10324.9 CDS26237.1 - 9.5e-05 21.8 7.3 9.5e-05 21.8 7.3 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw EcsB PF05975.12 CDS26237.1 - 4.6 6.0 13.3 1.7 7.4 7.5 2.8 3 1 0 3 3 3 0 Bacterial ABC transporter protein EcsB TSP_1 PF00090.19 CDS26238.2 - 4.9e-06 26.7 22.0 0.0045 17.2 5.6 2.9 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.6 CDS26238.2 - 0.0029 18.2 0.4 1 10.0 0.4 3.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDS26238.2 - 0.0051 16.9 0.0 0.69 10.0 0.0 2.9 3 0 0 3 3 3 1 Immunoglobulin I-set domain GntR PF00392.21 CDS26238.2 - 0.0073 15.9 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family Imm72 PF15584.6 CDS26238.2 - 0.046 13.9 0.4 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 72 Diphtheria_T PF02764.14 CDS26238.2 - 0.051 13.6 0.3 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Diphtheria toxin, T domain Herpes_LP PF03363.13 CDS26238.2 - 0.7 9.7 2.5 24 4.7 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus leader protein HHV-1_VABD PF16852.5 CDS26238.2 - 3 7.9 13.5 2 8.5 0.2 3.2 4 0 0 4 4 4 0 Herpes viral adaptor-to-host cellular mRNA binding domain zf-H2C2_5 PF13909.6 CDS26239.1 - 8.5e-06 25.4 0.4 8.5e-06 25.4 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CDS26239.1 - 0.00033 20.9 0.6 0.00033 20.9 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double domain DUF2492 PF10678.9 CDS26239.1 - 0.058 13.7 2.0 0.085 13.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) UPF0172 PF03665.13 CDS26240.1 - 9.1e-55 185.7 0.0 1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 CDS26240.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Serendipity_A PF05482.12 CDS26240.1 - 0.03 13.0 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) HECT PF00632.25 CDS26241.1 - 1.3e-93 313.9 0.0 1.9e-93 313.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CDS26241.1 - 2.1e-20 72.5 8.5 2e-12 47.0 1.0 2.9 3 0 0 3 3 3 2 WW domain C2 PF00168.30 CDS26241.1 - 1.6e-06 28.3 0.3 3.7e-06 27.2 0.3 1.6 1 0 0 1 1 1 1 C2 domain YcaO PF02624.16 CDS26241.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding MBD PF01429.19 CDS26241.1 - 0.65 9.7 5.0 2 8.2 0.1 3.1 3 0 0 3 3 3 0 Methyl-CpG binding domain Ras PF00071.22 CDS26242.1 - 8.7e-16 57.9 0.0 1.7e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_18 PF13238.6 CDS26242.1 - 0.015 15.8 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDS26242.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-rbx1 PF12678.7 CDS26243.1 - 7.4e-20 71.0 11.0 1.5e-19 70.1 11.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDS26243.1 - 4.4e-15 55.5 11.6 6.5e-15 55.0 11.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDS26243.1 - 6.3e-05 23.2 13.9 0.0019 18.5 13.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS26243.1 - 0.00081 19.2 1.4 0.00081 19.2 1.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS26243.1 - 0.029 14.2 11.0 0.24 11.3 11.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDS26243.1 - 0.034 14.0 1.4 0.08 12.8 1.4 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CDS26243.1 - 0.1 12.8 7.0 0.47 10.7 7.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDS26243.1 - 2 8.1 13.6 1.6 8.4 7.8 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CDS26243.1 - 5.5 7.1 9.6 56 3.9 9.6 2.3 1 1 0 1 1 1 0 RING-type zinc-finger GPCR_chapero_1 PF11904.8 CDS26244.2 - 3e-63 214.1 0.1 3.7e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 GPCR-chaperone HpcH_HpaI PF03328.14 CDS26245.2 - 1.6e-33 115.7 0.0 2.7e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DnaJ PF00226.31 CDS26245.2 - 5e-24 84.2 0.2 5e-24 84.2 0.2 2.3 3 0 0 3 3 3 1 DnaJ domain DUF1977 PF09320.11 CDS26245.2 - 2.4e-22 79.2 2.1 6.4e-22 77.8 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) C-C_Bond_Lyase PF15617.6 CDS26245.2 - 1.2e-08 34.6 0.0 0.00022 20.5 0.0 2.6 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold TPR_2 PF07719.17 CDS26245.2 - 0.0068 16.4 0.1 0.028 14.5 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Mu-like_Pro PF10123.9 CDS26245.2 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage I protein DUF1157 PF06636.11 CDS26245.2 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) TAXi_C PF14541.6 CDS26246.1 - 0.031 14.0 0.0 0.086 12.6 0.0 1.8 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal DUF2884 PF11101.8 CDS26246.1 - 0.065 12.7 0.3 0.11 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Amidase PF01425.21 CDS26247.1 - 1.3e-73 248.5 0.0 2.3e-73 247.7 0.0 1.4 1 1 0 1 1 1 1 Amidase Sybindin PF04099.12 CDS26248.1 - 5.3e-30 104.2 0.0 6.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CDS26248.1 - 5e-08 33.1 0.2 9.7e-08 32.2 0.1 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF5382 PF17354.2 CDS26249.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5382) RT_RNaseH_2 PF17919.1 CDS26255.1 - 2.4e-27 94.9 0.3 4.3e-27 94.1 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS26255.1 - 6.8e-25 87.4 0.1 1.7e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS26255.1 - 1.7e-19 70.2 0.0 3.5e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDS26255.1 - 0.012 16.2 0.0 0.26 11.8 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS26255.1 - 0.042 14.5 0.1 0.25 12.0 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 CDS26255.1 - 0.055 13.8 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 CDS26256.1 - 1.3e-08 34.8 0.1 1.7e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS26256.1 - 0.19 12.0 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 H2C2 zinc finger Y_phosphatase PF00102.27 CDS26262.2 - 1.4e-19 70.7 0.8 7.8e-09 35.4 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase ASFV_360 PF01671.16 CDS26267.2 - 0.084 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein CENP-F_leu_zip PF10473.9 CDS26269.1 - 6.3e-05 23.0 11.8 0.00013 22.0 11.8 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tmemb_cc2 PF10267.9 CDS26269.1 - 0.00016 20.9 20.5 0.00042 19.6 20.5 1.7 1 1 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Apolipoprotein PF01442.18 CDS26269.1 - 0.0037 17.2 12.5 0.0057 16.6 12.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Peptidase_M42 PF05343.14 CDS26269.1 - 0.026 13.5 0.6 0.66 8.9 0.2 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase HMMR_N PF15905.5 CDS26269.1 - 0.03 13.8 10.8 0.056 12.9 10.8 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 CDS26269.1 - 0.033 14.2 1.9 0.033 14.2 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CDS26269.1 - 0.071 11.1 4.5 0.1 10.6 4.5 1.3 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 CDS26269.1 - 0.096 12.7 7.1 0.11 12.5 6.0 1.7 1 1 0 1 1 1 0 Laminin Domain II Golgin_A5 PF09787.9 CDS26269.1 - 0.15 11.5 10.7 0.23 10.9 10.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 CDS26269.1 - 0.29 11.8 13.6 1.2 9.8 6.1 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1640 PF07798.11 CDS26269.1 - 0.34 10.9 12.2 0.92 9.5 12.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Stathmin PF00836.19 CDS26269.1 - 0.35 10.8 4.3 0.63 10.0 4.3 1.4 1 0 0 1 1 1 0 Stathmin family IFT57 PF10498.9 CDS26269.1 - 0.62 9.0 8.5 0.91 8.4 8.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LXG PF04740.12 CDS26269.1 - 0.62 9.7 8.0 0.68 9.6 5.4 2.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily Chordopox_L2 PF05803.12 CDS26269.1 - 0.8 9.6 4.8 0.45 10.4 2.1 1.9 1 1 1 2 2 2 0 Chordopoxvirus L2 protein DivIC PF04977.15 CDS26269.1 - 0.8 9.5 5.5 0.38 10.5 0.7 2.6 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 CDS26269.1 - 1.1 9.7 9.7 1 9.8 3.6 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CDS26269.1 - 1.4 8.9 15.3 4.6 7.3 2.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CDS26269.1 - 1.5 7.6 11.5 2.7 6.8 8.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 CDS26269.1 - 3.3 8.4 8.0 1.3 9.7 2.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF848 PF05852.11 CDS26269.1 - 4.1 7.5 8.5 6.3 6.9 7.5 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.13 CDS26269.1 - 4.5 6.4 5.6 4.4 6.5 4.3 1.6 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 CDS26269.1 - 4.9 7.3 9.8 16 5.6 9.4 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CDS26269.1 - 5.1 6.4 10.9 12 5.1 10.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 CDS26269.1 - 5.9 6.5 16.4 0.16 11.6 9.0 2.0 2 1 1 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease GTP_EFTU PF00009.27 CDS26270.1 - 8.1e-34 116.9 0.4 8.1e-34 116.9 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDS26270.1 - 8.1e-23 80.6 0.0 2.5e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDS26270.1 - 7.7e-08 32.4 0.1 1.7e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CDS26270.1 - 0.0043 16.8 0.2 0.36 10.6 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 CDS26270.1 - 0.025 14.6 0.0 0.84 9.7 0.0 2.5 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 CDS26270.1 - 0.047 13.4 0.1 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CDS26270.1 - 0.1 13.1 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mid1 PF12929.7 CDS26271.1 - 0.00079 18.7 1.5 0.0016 17.7 1.5 1.5 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Morc6_S5 PF17942.1 CDS26271.1 - 0.052 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like CNOT1_HEAT PF16418.5 CDS26272.1 - 0.016 15.3 0.2 0.39 10.8 0.0 2.0 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Methyltr_RsmB-F PF01189.17 CDS26273.1 - 5.6e-32 111.0 0.0 4.7e-29 101.5 0.0 3.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDS26273.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase SRP_TPR_like PF17004.5 CDS26274.1 - 6.4e-20 71.3 0.6 6.4e-20 71.3 0.6 2.6 2 1 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 CDS26274.1 - 7.2e-19 68.0 6.7 7.2e-19 68.0 6.7 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 CDS26274.1 - 2.8e-08 33.3 15.2 0.03 14.4 1.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS26274.1 - 1.4e-07 31.1 7.2 0.009 16.2 1.3 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS26274.1 - 4.5e-07 30.0 5.8 0.024 14.8 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CDS26274.1 - 0.00011 22.7 1.0 24 6.1 0.0 6.3 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS26274.1 - 0.00015 21.4 17.5 1.9 8.5 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS26274.1 - 0.00047 20.8 0.0 21 5.9 0.0 5.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Cohesin_load PF10345.9 CDS26274.1 - 0.00089 17.8 1.1 0.0015 17.1 1.1 1.3 1 0 0 1 1 1 1 Cohesin loading factor TPR_11 PF13414.6 CDS26274.1 - 0.0032 17.1 2.6 0.26 11.0 0.1 3.6 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 CDS26274.1 - 0.0055 16.7 6.6 6.8 7.0 0.2 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS26274.1 - 0.037 14.3 8.6 1.8 8.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS26274.1 - 0.22 11.4 0.6 2.5 8.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS26274.1 - 1.7 9.5 9.1 31 5.5 0.1 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat BAF PF02961.14 CDS26275.1 - 1.9e-39 133.9 0.0 2.4e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Barrier to autointegration factor IMS_HHH PF11798.8 CDS26275.1 - 6.3e-05 23.1 0.3 0.0003 21.0 0.1 2.0 2 0 0 2 2 2 1 IMS family HHH motif Voltage_CLC PF00654.20 CDS26276.2 - 2.3e-83 280.4 23.4 2.3e-83 280.4 23.4 2.0 3 0 0 3 3 3 1 Voltage gated chloride channel CBS PF00571.28 CDS26276.2 - 1.3e-11 44.8 0.2 0.00025 21.4 0.1 2.7 2 0 0 2 2 2 2 CBS domain Histone PF00125.24 CDS26277.2 - 3e-17 63.2 0.0 3.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS26277.2 - 2.7e-05 24.4 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2517 PF10725.9 CDS26278.2 - 0.091 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) C2 PF00168.30 CDS26279.1 - 2.5e-07 30.9 0.0 1.4e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 C2 domain GIT_CC PF16559.5 CDS26282.1 - 0.0011 18.8 0.3 0.0032 17.3 0.3 1.8 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 CDS26282.1 - 0.031 14.1 0.3 0.07 13.0 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CDS26282.1 - 0.09 13.4 0.3 0.33 11.6 0.3 1.9 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 CDS26282.1 - 0.097 13.0 0.0 0.38 11.1 0.0 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4407 PF14362.6 CDS26282.1 - 2.1 7.6 6.1 3.9 6.8 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L7Ae PF01248.26 CDS26283.1 - 1e-20 73.3 0.3 1.3e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PqqD PF05402.12 CDS26283.1 - 0.019 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Septin PF00735.18 CDS26284.1 - 4.5e-103 344.4 0.0 6.6e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CDS26284.1 - 3.2e-05 24.0 0.0 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDS26284.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 CDS26284.1 - 0.0035 16.9 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Strep_SA_rep PF06696.11 CDS26284.1 - 0.0043 17.0 0.2 0.0094 15.9 0.2 1.6 1 0 0 1 1 1 1 Streptococcal surface antigen repeat AAA_24 PF13479.6 CDS26284.1 - 0.0068 16.2 0.4 0.09 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CDS26284.1 - 0.0097 15.3 0.0 0.034 13.5 0.0 1.9 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CDS26284.1 - 0.013 15.4 0.0 0.049 13.5 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDS26284.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDS26284.1 - 0.023 15.1 0.1 0.059 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 CDS26285.1 - 4e-54 179.4 23.0 1.6e-11 44.5 0.1 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS26285.1 - 5.4e-29 100.3 0.3 1.7e-08 34.7 0.1 6.9 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS26285.1 - 9.6e-12 45.2 0.8 8.9e-06 25.7 0.6 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 CDS26285.1 - 5.1e-08 32.6 0.3 1.1e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 CDS26285.1 - 1.2e-06 28.1 0.0 0.43 9.9 0.0 4.4 4 1 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CDS26285.1 - 1.6e-05 24.0 0.8 0.55 9.1 0.5 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDS26285.1 - 0.00014 20.7 9.0 0.96 8.0 0.2 5.5 3 2 3 6 6 6 3 Nucleoporin Nup120/160 IKI3 PF04762.12 CDS26285.1 - 0.0017 16.5 0.6 0.023 12.7 0.1 2.3 2 1 0 3 3 3 1 IKI3 family Coatomer_WDAD PF04053.14 CDS26285.1 - 0.047 12.7 0.0 1.4 7.8 0.0 2.4 1 1 0 2 2 2 0 Coatomer WD associated region Herpes_capsid PF06112.11 CDS26285.1 - 7.5 6.6 12.5 15 5.6 12.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein mRNA_cap_enzyme PF01331.19 CDS26286.1 - 3.7e-43 147.6 0.0 5.4e-42 143.8 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CDS26286.1 - 3.3e-16 59.9 0.0 8.6e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CDS26286.1 - 3.3e-13 49.6 0.1 5.8e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS26286.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDS26286.1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DNA_ligase_A_M PF01068.21 CDS26286.1 - 0.0094 15.6 0.0 0.46 10.1 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Y_phosphatase3 PF13350.6 CDS26286.1 - 0.06 13.3 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family EGF PF00008.27 CDS26287.1 - 4.9e-93 304.9 312.0 1.2e-07 31.9 10.1 23.9 22 1 0 22 22 22 21 EGF-like domain hEGF PF12661.7 CDS26287.1 - 1.3e-48 162.0 263.5 1.4e-05 25.5 8.7 25.6 24 3 0 24 24 24 19 Human growth factor-like EGF EGF_2 PF07974.13 CDS26287.1 - 3.6e-24 84.8 378.5 0.0039 17.5 10.1 24.3 24 1 0 24 24 22 18 EGF-like domain Ank_2 PF12796.7 CDS26287.1 - 1.1e-21 77.2 10.5 4.3e-11 43.2 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS26287.1 - 1.5e-21 76.4 0.4 9.7e-05 22.9 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) NOD PF06816.13 CDS26287.1 - 1.4e-17 63.0 0.1 2.9e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 NOTCH protein Ank_5 PF13857.6 CDS26287.1 - 1.5e-16 60.2 3.7 2.5e-05 24.5 0.3 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CDS26287.1 - 1.5e-15 56.8 5.9 0.0034 17.8 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CDS26287.1 - 5.4e-15 54.0 2.3 0.016 15.7 0.1 6.8 6 0 0 6 6 6 3 Ankyrin repeat Notch PF00066.17 CDS26287.1 - 3.5e-13 49.8 25.8 1.8e-10 41.1 8.7 8.7 10 0 0 10 10 3 2 LNR domain EGF_CA PF07645.15 CDS26287.1 - 1.5e-12 47.5 52.5 1.4e-07 31.6 5.9 22.1 11 5 12 23 23 19 8 Calcium-binding EGF domain DUF3454 PF11936.8 CDS26287.1 - 7 7.1 12.6 1.2 9.5 4.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) UQ_con PF00179.26 CDS26288.1 - 1.5e-47 160.8 0.0 1.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDS26288.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CDS26288.1 - 0.19 11.4 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B COG6 PF06419.11 CDS26289.1 - 2.3e-105 353.2 14.8 4.9e-101 338.9 9.4 2.1 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 PKK PF12474.8 CDS26289.1 - 0.11 12.6 1.5 0.26 11.4 1.5 1.6 1 0 0 1 1 1 0 Polo kinase kinase DUF4064 PF13273.6 CDS26290.1 - 1.2e-05 25.5 3.4 0.0018 18.5 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) COPI_assoc PF08507.10 CDS26290.1 - 9.8e-05 22.4 1.6 0.036 14.1 0.1 2.9 3 0 0 3 3 3 1 COPI associated protein DUF202 PF02656.15 CDS26290.1 - 0.00054 20.4 1.5 0.034 14.6 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) GPDPase_memb PF10110.9 CDS26290.1 - 0.00062 18.6 0.5 0.004 16.0 0.1 1.9 2 0 0 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Tetraspanin PF00335.20 CDS26290.1 - 0.00069 19.4 2.1 0.039 13.7 1.7 2.2 2 0 0 2 2 2 1 Tetraspanin family PIG-Y PF15159.6 CDS26290.1 - 0.00099 20.0 0.1 3.2 8.8 0.0 2.9 3 0 0 3 3 3 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TRP PF06011.12 CDS26290.1 - 0.0036 16.1 0.0 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF308 PF03729.13 CDS26290.1 - 0.0073 16.6 12.2 3.2 8.2 1.2 3.1 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) TctB PF07331.11 CDS26290.1 - 0.0078 16.5 0.1 0.32 11.3 0.1 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family DUF423 PF04241.15 CDS26290.1 - 0.0082 16.3 2.7 1.5 9.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF423) DUF3169 PF11368.8 CDS26290.1 - 0.011 15.2 1.9 0.034 13.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2157 PF09925.9 CDS26290.1 - 0.013 15.3 3.0 1.8 8.3 1.6 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Ferric_reduct PF01794.19 CDS26290.1 - 0.017 15.3 0.3 2.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF4834 PF16118.5 CDS26290.1 - 0.017 16.1 1.8 1.4 9.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) O_anti_polymase PF01901.16 CDS26290.1 - 0.02 14.2 1.5 0.5 9.6 0.9 2.0 2 0 0 2 2 2 0 Putative O-antigen polymerase DUF2207 PF09972.9 CDS26290.1 - 0.023 13.5 3.3 0.87 8.3 4.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Amastin PF07344.11 CDS26290.1 - 0.03 14.2 1.2 0.39 10.6 0.5 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein OATP PF03137.20 CDS26290.1 - 0.032 12.5 0.6 0.085 11.1 0.5 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.13 CDS26290.1 - 0.036 14.7 2.7 0.036 14.7 2.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Orai-1 PF07856.12 CDS26290.1 - 0.037 13.7 2.7 0.41 10.3 2.7 2.1 1 1 0 1 1 1 0 Mediator of CRAC channel activity TMEM51 PF15345.6 CDS26290.1 - 0.041 13.7 0.0 0.096 12.5 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 TssO PF17561.2 CDS26290.1 - 0.05 13.7 6.5 1.1 9.3 0.1 2.9 2 1 1 3 3 3 0 Type VI secretion system, TssO LMBR1 PF04791.16 CDS26290.1 - 0.05 12.5 0.8 0.12 11.2 0.3 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein FxsA PF04186.13 CDS26290.1 - 0.051 13.7 0.1 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF4282 PF14110.6 CDS26290.1 - 0.053 14.2 5.2 0.18 12.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF898 PF05987.13 CDS26290.1 - 0.058 12.4 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) TMEM52 PF14979.6 CDS26290.1 - 0.081 12.8 0.6 5.2 7.0 0.5 2.7 2 1 0 2 2 2 0 Transmembrane 52 DUF4231 PF14015.6 CDS26290.1 - 0.082 13.4 0.8 0.23 11.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) EphA2_TM PF14575.6 CDS26290.1 - 0.1 13.5 0.2 55 4.7 0.7 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DHHC PF01529.20 CDS26290.1 - 0.13 12.3 4.6 0.63 10.1 1.2 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase STE2 PF02116.15 CDS26290.1 - 0.3 10.3 8.0 0.23 10.8 0.9 2.1 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR DUF5090 PF17009.5 CDS26290.1 - 0.32 10.9 5.5 0.94 9.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) ATP-synt_8 PF00895.20 CDS26290.1 - 0.34 11.4 7.5 1.3 9.6 0.2 3.0 3 0 0 3 3 2 0 ATP synthase protein 8 DUF1218 PF06749.12 CDS26290.1 - 0.38 11.3 5.5 1.1 9.9 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF3185 PF11381.8 CDS26290.1 - 0.57 10.2 15.4 9.6 6.3 1.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) DUF3899 PF13038.6 CDS26290.1 - 0.63 10.6 0.0 0.63 10.6 0.0 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) DUF2892 PF11127.8 CDS26290.1 - 0.67 10.0 8.3 18 5.5 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF3040 PF11239.8 CDS26290.1 - 0.85 9.9 6.1 51 4.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Sigma_reg_N PF13800.6 CDS26290.1 - 1.1 9.6 6.1 29 5.0 0.3 3.0 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Phage_holin_3_6 PF07332.11 CDS26290.1 - 2 8.5 6.7 7.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III IncE PF17627.2 CDS26290.1 - 6.7 6.7 8.3 70 3.4 6.1 2.8 2 1 0 2 2 2 0 Inclusion membrane protein E SUR7 PF06687.12 CDS26292.1 - 0.0013 18.4 0.9 0.0016 18.1 0.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5316 PF17247.2 CDS26292.1 - 0.0014 18.6 0.9 0.0026 17.7 0.9 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5316) GPDPase_memb PF10110.9 CDS26292.1 - 0.0071 15.2 0.1 0.008 15.0 0.1 1.0 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase COPI_assoc PF08507.10 CDS26292.1 - 0.019 15.1 1.0 0.025 14.6 1.0 1.2 1 0 0 1 1 1 0 COPI associated protein DUF4282 PF14110.6 CDS26292.1 - 0.04 14.6 1.2 0.054 14.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF4834 PF16118.5 CDS26292.1 - 0.043 14.8 0.4 1.6 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Prominin PF05478.11 CDS26292.1 - 0.065 11.2 3.2 0.073 11.0 3.2 1.0 1 0 0 1 1 1 0 Prominin Trp_oprn_chp PF09534.10 CDS26292.1 - 0.066 13.0 0.1 0.54 10.0 0.0 1.9 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF898 PF05987.13 CDS26292.1 - 0.079 12.0 0.0 0.092 11.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Tetraspanin PF00335.20 CDS26292.1 - 0.08 12.6 5.5 0.1 12.3 5.5 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1418 PF07214.12 CDS26292.1 - 0.21 11.5 1.5 0.53 10.2 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) MSP1a PF11670.8 CDS26292.1 - 0.26 10.5 3.5 0.83 8.9 3.6 1.7 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) TMEM52 PF14979.6 CDS26292.1 - 0.3 11.0 0.1 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 Transmembrane 52 DUF1700 PF08006.11 CDS26292.1 - 0.42 10.1 4.2 0.6 9.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3377 PF11857.8 CDS26292.1 - 0.59 10.1 3.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF2207 PF09972.9 CDS26292.1 - 0.6 8.8 4.5 1 8.1 4.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 CDS26292.1 - 1.9 8.3 7.1 0.65 9.8 0.2 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CRPA PF05745.11 CDS26292.1 - 2.5 8.1 7.3 6.2 6.8 0.6 2.2 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4811 PF16069.5 CDS26292.1 - 3 7.7 4.6 21 5.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) DUF3040 PF11239.8 CDS26292.1 - 4.3 7.7 8.0 12 6.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF2975 PF11188.8 CDS26292.1 - 4.5 7.2 8.8 1.5 8.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF4389 PF14333.6 CDS26292.1 - 5.6 7.0 5.7 2.8 7.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF1700 PF08006.11 CDS26293.2 - 0.0028 17.2 2.5 0.0034 16.9 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) Tetraspanin PF00335.20 CDS26293.2 - 0.0044 16.7 2.6 0.0053 16.5 2.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 CDS26293.2 - 0.014 14.2 1.4 0.015 14.1 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3899 PF13038.6 CDS26293.2 - 0.43 11.1 4.1 1.5 9.4 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) DUF872 PF05915.12 CDS26293.2 - 6.2 7.0 7.7 5.2 7.3 0.3 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) zf-C2H2_3rep PF18868.1 CDS26294.1 - 0.051 14.2 0.2 0.22 12.2 0.0 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF1644 PF07800.12 CDS26294.1 - 0.2 11.7 4.9 2.8 8.0 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) Zn_ribbon_SprT PF17283.2 CDS26294.1 - 0.22 11.4 0.1 0.22 11.4 0.1 3.7 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 CDS26294.1 - 3 7.5 6.5 13 5.5 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Amino_oxidase PF01593.24 CDS26295.2 - 3.6e-16 59.5 0.0 6.1e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDS26295.2 - 2.4e-11 43.7 0.2 4.2e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDS26295.2 - 2.2e-05 24.2 0.1 5e-05 23.0 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDS26295.2 - 0.00033 20.0 0.1 0.076 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDS26295.2 - 0.0008 19.4 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 CDS26295.2 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 CDS26295.2 - 0.19 10.5 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 CDS26295.2 - 0.28 11.8 0.5 2 9.1 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CDS26296.1 - 5.1e-54 182.9 0.1 6.6e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CDS26296.1 - 5.8e-29 100.6 0.0 1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 CDS26296.1 - 2.2e-06 27.8 0.0 6.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 CDS26296.1 - 2.8e-05 24.3 0.1 6.5e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 CDS26296.1 - 0.0036 16.9 0.2 0.0069 16.0 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CDS26296.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CDS26296.1 - 0.021 15.4 0.1 0.048 14.2 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CbiA PF01656.23 CDS26296.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pyr_redox_2 PF07992.14 CDS26296.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1258 PF06869.12 CDS26296.1 - 0.051 13.0 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) DFP PF04127.15 CDS26296.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 CDS26296.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 CDS26296.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF4131 PF13567.6 CDS26297.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YiaAB PF05360.14 CDS26297.1 - 1.6 9.0 5.1 1.2 9.4 3.0 1.9 1 1 0 1 1 1 0 yiaA/B two helix domain KASH_CCD PF14662.6 CDS26298.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Exo_endo_phos_2 PF14529.6 CDS26299.1 - 4.3e-13 49.1 0.0 5.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PFO_beta_C PF12367.8 CDS26299.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Exo_endo_phos PF03372.23 CDS26299.1 - 0.025 14.1 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDS26300.1 - 1.5e-25 90.0 0.1 3.5e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) KH_6 PF15985.5 CDS26302.1 - 1.1e-06 28.9 0.3 3e-06 27.5 0.3 1.8 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 CDS26302.1 - 5.2e-06 26.2 0.2 1.5e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region HTH_Tnp_Tc3_2 PF01498.18 CDS26303.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Transposase Ski_Sno PF02437.17 CDS26304.2 - 9.9e-36 121.8 0.3 2.3e-35 120.6 0.3 1.6 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 CDS26304.2 - 5.6e-30 103.4 1.4 5.6e-30 103.4 1.4 1.8 2 0 0 2 2 2 1 c-SKI Smad4 binding domain DNA_ligase_A_M PF01068.21 CDS26305.1 - 2.6e-56 190.5 0.0 4.3e-37 127.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDS26305.1 - 5.4e-45 153.8 0.1 8.5e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDS26305.1 - 2.2e-26 92.3 0.0 7.4e-26 90.6 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 CDS26305.1 - 0.035 14.1 0.2 13 5.9 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain polyprenyl_synt PF00348.17 CDS26306.1 - 1.6e-60 204.3 0.0 2.2e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Rad10 PF03834.14 CDS26306.1 - 7.1e-40 135.6 0.0 1.3e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CDS26306.1 - 5.6e-07 30.1 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CDS26306.1 - 1.7e-05 24.8 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 CDS26306.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_5 PF13893.6 CDS26307.1 - 6.3e-38 129.2 8.1 3.8e-27 94.4 0.1 4.3 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDS26307.1 - 1.3e-23 82.5 0.1 1.4e-06 28.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS26307.1 - 1.1e-06 28.4 1.8 0.0022 17.8 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_8 PF11835.8 CDS26307.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 RRM-like domain Dehydratase_MU PF02288.15 CDS26307.1 - 0.085 12.8 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Dehydratase medium subunit GDA1_CD39 PF01150.17 CDS26308.1 - 2e-98 329.9 0.0 2.7e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DnaJ_C PF01556.18 CDS26308.1 - 8e-40 136.3 0.1 1.4e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDS26308.1 - 2.8e-27 94.6 4.0 4.9e-27 93.9 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF485 PF04341.12 CDS26308.1 - 0.02 14.8 1.1 0.083 12.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 G-patch PF01585.23 CDS26309.1 - 3.1e-08 33.4 1.4 4.9e-05 23.1 1.3 2.3 2 0 0 2 2 2 2 G-patch domain Tugs PF17840.1 CDS26309.1 - 0.052 13.7 1.7 3.9 7.7 0.1 2.6 2 1 0 2 2 2 0 Tethering Ubl4a to BAGS domain SET PF00856.28 CDS26310.1 - 1.4e-12 48.3 2.6 2.3e-12 47.6 0.7 2.4 2 1 0 2 2 2 1 SET domain TPR_8 PF13181.6 CDS26310.1 - 0.058 13.6 3.5 0.62 10.4 0.7 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BRCT_2 PF16589.5 CDS26310.1 - 0.12 12.8 0.2 0.94 9.9 0.1 2.5 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain PPP5 PF08321.12 CDS26310.1 - 0.23 11.8 2.5 0.5 10.7 2.5 1.6 1 0 0 1 1 1 0 PPP5 TPR repeat region Myb_DNA-binding PF00249.31 CDS26312.1 - 2.2e-05 24.6 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ELM2 PF01448.24 CDS26312.1 - 5e-05 24.0 0.1 0.00016 22.3 0.1 2.0 1 0 0 1 1 1 1 ELM2 domain DUF5591 PF17884.1 CDS26312.1 - 0.00098 19.0 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Myb_DNA-bind_7 PF15963.5 CDS26312.1 - 0.0065 16.3 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CDS26312.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PGM_PMM_I PF02878.16 CDS26314.1 - 1.3e-20 73.5 0.0 3.5e-11 43.0 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CDS26314.1 - 1.5e-07 31.5 0.1 3.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CDS26314.1 - 0.029 15.0 0.0 2.5 8.8 0.0 3.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CDS26314.1 - 0.034 14.3 0.0 0.21 11.8 0.0 2.3 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III cobW PF02492.19 CDS26316.1 - 1.6e-49 167.9 0.1 2e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CDS26316.1 - 1.2e-11 44.3 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CDS26316.1 - 0.00022 21.2 1.7 0.43 10.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 CDS26316.1 - 0.014 15.3 0.5 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CDS26316.1 - 0.021 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CDS26316.1 - 0.028 13.4 0.7 0.4 9.6 0.1 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CDS26316.1 - 0.03 14.1 1.6 5.1 6.8 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 CDS26316.1 - 0.034 14.5 2.0 7 7.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDS26316.1 - 0.04 13.7 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDS26316.1 - 0.044 14.1 0.7 0.23 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 CDS26316.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CDS26316.1 - 0.056 14.0 0.7 0.44 11.1 0.7 2.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CDS26316.1 - 0.062 13.8 1.2 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDS26316.1 - 0.095 12.8 0.3 0.75 9.9 0.0 2.5 1 1 1 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 CDS26316.1 - 0.13 11.3 1.2 0.17 10.9 0.4 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 CDS26316.1 - 0.15 12.6 0.2 0.51 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDS26316.1 - 0.25 11.0 0.2 1.2 8.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain SWIB PF02201.18 CDS26317.1 - 8.1e-21 73.7 0.3 4.5e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 SWIB/MDM2 domain XPG_I_2 PF12813.7 CDS26317.1 - 0.012 15.1 0.8 0.021 14.3 0.8 1.3 1 0 0 1 1 1 0 XPG domain containing DUF4239 PF14023.6 CDS26317.1 - 0.14 11.8 0.6 1 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) RhoGAP PF00620.27 CDS26319.1 - 1.2e-20 73.8 0.0 6.9e-19 68.2 0.0 2.4 1 1 0 1 1 1 1 RhoGAP domain DUF4509 PF14970.6 CDS26320.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) PTH2 PF01981.16 CDS26323.1 - 1.3e-19 70.6 0.0 1.5e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GvpG PF05120.12 CDS26323.1 - 0.051 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Ank_4 PF13637.6 CDS26324.1 - 5e-43 144.9 3.2 1.3e-08 35.2 0.0 9.5 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS26324.1 - 1.1e-39 134.8 6.1 9e-09 35.8 0.1 6.0 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 CDS26324.1 - 2.1e-29 100.6 8.0 0.0011 19.4 0.0 10.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 CDS26324.1 - 3.3e-26 88.5 5.1 0.0022 18.3 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 CDS26324.1 - 2.1e-22 78.9 5.3 0.013 15.8 0.0 8.6 6 1 2 8 8 8 6 Ankyrin repeats (many copies) THEG PF14912.6 CDS26324.1 - 0.043 14.3 0.1 0.18 12.3 0.1 2.1 1 0 0 1 1 1 0 Testicular haploid expressed repeat MAGI_u1 PF16663.5 CDS26324.1 - 2.8 8.1 6.5 0.81 9.8 1.9 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI DnaJ_C PF01556.18 CDS26325.2 - 3.1e-38 131.2 0.1 4e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain EF-hand_9 PF14658.6 CDS26326.1 - 7.6e-06 26.2 0.0 0.058 13.7 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 CDS26326.1 - 3.7e-05 23.3 0.5 0.034 14.1 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDS26326.1 - 7.6e-05 23.1 0.1 0.0097 16.3 0.2 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS26326.1 - 0.1 12.4 3.6 2.5 8.0 0.2 3.8 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 CDS26326.1 - 0.15 11.7 3.7 6.9 6.5 0.0 3.9 4 0 0 4 4 4 0 EF hand DER1 PF04511.15 CDS26327.1 - 3.7e-66 222.7 16.7 4.3e-66 222.5 16.7 1.0 1 0 0 1 1 1 1 Der1-like family WD40 PF00400.32 CDS26330.1 - 2.7e-35 119.8 17.0 1.4e-06 28.9 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS26330.1 - 4.7e-09 36.4 0.7 0.048 13.9 0.0 4.7 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS26330.1 - 0.00037 19.3 2.2 0.058 12.0 0.2 3.4 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Hira PF07569.11 CDS26330.1 - 0.0044 16.8 0.3 5.3 6.7 0.0 3.2 3 1 0 3 3 3 2 TUP1-like enhancer of split ABC_tran_CTD PF16326.5 CDS26330.1 - 0.048 13.9 0.2 0.096 12.9 0.2 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Cnn_1N PF07989.11 CDS26330.1 - 0.081 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YqzH PF14164.6 CDS26330.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein Cu_amine_oxidN3 PF02728.16 CDS26331.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 1 1 2 2 2 0 Copper amine oxidase, N3 domain FA_desaturase PF00487.24 CDS26332.1 - 7.6e-22 78.4 22.0 7.6e-22 78.4 22.0 1.4 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 CDS26332.1 - 6.6e-20 70.3 2.0 1.3e-19 69.4 2.0 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Astacin PF01400.24 CDS26332.1 - 0.15 11.6 1.1 0.22 11.1 1.1 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 CDS26332.1 - 0.31 9.9 0.9 0.53 9.2 0.9 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CDS26332.1 - 0.41 9.2 2.0 0.58 8.7 2.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Piwi PF02171.17 CDS26333.1 - 7.8e-114 380.0 0.0 1.3e-113 379.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 CDS26333.1 - 6.4e-34 116.1 0.2 1.8e-33 114.6 0.2 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 CDS26333.1 - 1.2e-26 93.1 0.8 2e-26 92.4 0.8 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CDS26333.1 - 4.8e-26 92.0 0.0 1.5e-25 90.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDS26333.1 - 1.9e-23 81.9 0.2 1.4e-22 79.1 0.1 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CDS26333.1 - 2.1e-14 53.6 0.5 5.2e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain Phage_holin_3_6 PF07332.11 CDS26333.1 - 0.81 9.7 2.9 1.4 9.0 2.9 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 CDS26335.1 - 3e-38 131.7 0.0 3.9e-28 98.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26335.1 - 3.2e-16 59.4 0.0 1.7e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26335.1 - 0.022 14.1 0.0 0.62 9.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CDS26335.1 - 0.045 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS26335.1 - 0.096 11.4 0.0 0.096 11.4 0.0 1.8 2 1 0 2 2 2 0 Fungal protein kinase Pepsin-I3 PF06394.13 CDS26335.1 - 0.63 10.3 2.3 1.8 8.9 2.3 1.7 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Complex1_51K PF01512.17 CDS26336.1 - 8.3e-49 165.3 0.0 1.6e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CDS26336.1 - 2e-28 98.3 1.5 8.2e-28 96.3 0.9 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CDS26336.1 - 4.5e-07 29.6 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 SLBB domain BAH PF01426.18 CDS26337.1 - 7e-05 22.7 1.6 0.00016 21.5 1.6 1.6 1 0 0 1 1 1 1 BAH domain Myb_DNA-bind_7 PF15963.5 CDS26337.1 - 0.057 13.3 2.7 0.085 12.8 0.0 2.6 3 0 0 3 3 3 0 Myb DNA-binding like Alph_Pro_TM PF09608.10 CDS26337.1 - 0.12 12.1 2.4 0.32 10.8 2.4 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) FA_desaturase PF00487.24 CDS26339.2 - 9e-21 74.8 24.3 7.5e-20 71.8 24.7 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 CDS26339.2 - 8.7e-17 60.3 2.0 1.8e-16 59.3 2.0 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Metallopep PF12044.8 CDS26339.2 - 0.032 12.8 0.6 0.053 12.1 0.6 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 CDS26339.2 - 0.097 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-CCCH PF00642.24 CDS26340.1 - 0.17 11.8 1.4 0.35 10.8 1.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DPPIV_N PF00930.21 CDS26341.1 - 8.2e-53 179.4 1.8 1.3e-52 178.7 1.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CDS26341.1 - 2.3e-44 151.4 0.0 3.3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ig_3 PF13927.6 CDS26341.1 - 1.6e-19 70.2 0.7 1.3e-11 44.9 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDS26341.1 - 5.8e-13 48.7 0.0 5e-08 32.9 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 CDS26341.1 - 3.9e-11 43.0 0.1 4.1e-07 30.1 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDS26341.1 - 5.3e-10 39.5 0.8 4.8e-07 30.0 0.0 3.5 3 0 0 3 3 3 1 Immunoglobulin domain Hydrolase_4 PF12146.8 CDS26341.1 - 2e-06 27.3 0.6 0.00092 18.5 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 CDS26341.1 - 3.3e-05 23.6 0.0 7.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CDS26341.1 - 0.0003 20.5 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 CDS26341.1 - 0.0013 18.4 0.0 0.0044 16.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CDS26341.1 - 0.0014 19.3 0.1 0.0029 18.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family V-set PF07686.17 CDS26341.1 - 0.0021 18.2 0.9 21 5.3 0.0 4.6 4 1 0 4 4 4 0 Immunoglobulin V-set domain Abhydrolase_1 PF00561.20 CDS26341.1 - 0.0036 17.0 0.1 0.0089 15.7 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CDS26341.1 - 0.0042 17.0 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ig_6 PF18452.1 CDS26341.1 - 0.0073 15.8 0.0 0.081 12.5 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain AXE1 PF05448.12 CDS26341.1 - 0.009 14.7 0.0 0.07 11.8 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 CDS26341.1 - 0.0097 15.7 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ig_C17orf99 PF17736.1 CDS26341.1 - 0.038 14.0 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 C17orf99 Ig domain DUF2920 PF11144.8 CDS26341.1 - 0.21 10.7 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) TPD52 PF04201.15 CDS26342.1 - 3.7e-16 59.1 4.1 1.1e-13 51.1 0.1 2.1 1 1 1 2 2 2 2 Tumour protein D52 family DUF5082 PF16888.5 CDS26342.1 - 0.053 13.8 2.7 0.13 12.5 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 CDS26342.1 - 0.066 13.4 1.9 3 8.0 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 CDS26342.1 - 0.082 13.1 1.8 0.09 13.0 0.6 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 CDS26342.1 - 0.094 13.3 1.3 0.094 13.3 1.3 2.2 1 1 0 2 2 2 0 SlyX FlaC_arch PF05377.11 CDS26342.1 - 0.096 13.1 1.4 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC24 PF15669.5 CDS26342.1 - 0.15 11.9 1.6 0.31 10.9 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF1319 PF07028.11 CDS26342.1 - 0.15 12.2 1.5 0.17 12.1 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) ATG16 PF08614.11 CDS26342.1 - 0.28 11.4 4.6 0.096 12.9 1.6 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 CDS26342.1 - 0.44 10.4 6.6 0.82 9.6 2.2 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Enkurin PF13864.6 CDS26343.1 - 7.2e-21 74.5 6.6 7.2e-21 74.5 6.6 1.8 2 0 0 2 2 2 1 Calmodulin-binding TIP120 PF08623.10 CDS26345.2 - 1.9e-41 141.7 1.8 7.3e-40 136.5 0.3 3.5 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 CDS26345.2 - 1.9e-08 34.6 0.1 0.34 11.3 0.0 7.1 7 0 0 7 7 7 2 HEAT repeats HEAT PF02985.22 CDS26345.2 - 0.00024 21.1 4.3 24 5.5 0.0 7.2 8 0 0 8 8 8 0 HEAT repeat TAF6_C PF07571.13 CDS26345.2 - 0.0092 16.3 0.0 1.3 9.4 0.0 3.9 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain MOR2-PAG1_C PF14225.6 CDS26345.2 - 0.037 13.9 0.2 0.037 13.9 0.2 3.6 3 1 0 3 3 3 0 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 CDS26345.2 - 0.074 13.6 0.9 99 3.6 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat MazG_C PF18722.1 CDS26345.2 - 0.14 11.7 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 MazG C-terminal domain Arm PF00514.23 CDS26345.2 - 9.4 6.4 6.4 1.8e+02 2.4 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat PDEase_I PF00233.19 CDS26346.1 - 2.6e-83 279.4 5.4 2.6e-83 279.4 5.4 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 CDS26346.1 - 9e-26 89.5 0.3 2.1e-25 88.3 0.3 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF3150 PF11348.8 CDS26346.1 - 0.078 12.2 0.3 0.26 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) Orbi_VP6 PF01516.16 CDS26346.1 - 0.44 10.0 6.4 0.77 9.2 6.4 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 Ank_2 PF12796.7 CDS26347.2 - 8.9e-42 141.6 6.1 5.1e-14 52.6 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS26347.2 - 1.2e-33 111.4 12.4 1.9e-06 27.8 0.1 11.3 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 CDS26347.2 - 6e-31 106.4 4.3 5.6e-09 36.4 0.0 5.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS26347.2 - 9e-29 99.2 7.1 6.1e-08 32.8 0.2 7.6 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 CDS26347.2 - 1.8e-24 85.1 7.3 7.5e-06 26.2 0.1 10.0 10 0 0 10 10 10 4 Ankyrin repeat Death PF00531.22 CDS26347.2 - 0.00024 21.2 0.2 0.0007 19.7 0.2 1.8 1 0 0 1 1 1 1 Death domain 14-3-3 PF00244.20 CDS26348.1 - 1.7e-93 312.2 8.5 1.9e-93 312.0 8.5 1.0 1 0 0 1 1 1 1 14-3-3 protein 7tm_1 PF00001.21 CDS26350.1 - 6.3e-06 25.7 15.4 8.8e-06 25.2 15.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) tRNA-synt_2b PF00587.25 CDS26352.1 - 8.7e-34 117.0 0.0 1.3e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HypA PF01155.19 CDS26352.1 - 0.16 12.0 1.4 0.31 11.1 1.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 CDS26353.1 - 2.9e-31 108.5 1.1 3.7e-31 108.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 CDS26353.1 - 0.13 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DDE_Tnp_1_7 PF13843.6 CDS26355.1 - 3.1e-12 46.5 0.0 3.6e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Pkinase_Tyr PF07714.17 CDS26357.1 - 8.5e-77 257.9 0.0 1.2e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS26357.1 - 2e-28 99.5 0.0 4.9e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 CDS26357.1 - 3.2e-13 49.5 0.0 6.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS26357.1 - 3.1e-11 43.7 0.0 9.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDS26357.1 - 3.8e-09 36.8 0.0 1.5e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDS26357.1 - 2.4e-05 24.4 0.0 8.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Fz PF01392.22 CDS26357.1 - 0.0038 17.8 3.9 0.012 16.2 3.9 1.9 1 0 0 1 1 1 1 Fz domain Radial_spoke PF04712.12 CDS26358.1 - 1.3e-145 486.2 0.2 1.3e-145 486.2 0.2 2.4 2 0 0 2 2 2 1 Radial spokehead-like protein DUF2046 PF09755.9 CDS26358.1 - 2.4e-82 276.6 46.5 1.8e-69 234.3 33.5 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Baculo_PEP_C PF04513.12 CDS26358.1 - 0.37 10.8 12.6 0.41 10.7 6.6 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MDMPI_N PF11716.8 CDS26358.1 - 4.7 7.9 7.4 0.55 10.9 0.1 2.7 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain WD40 PF00400.32 CDS26360.1 - 4.9e-17 62.0 13.7 0.0004 21.1 0.2 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS26360.1 - 3e-13 49.9 0.9 0.049 13.9 0.0 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS26360.1 - 0.0052 16.7 0.0 3.4 7.5 0.0 3.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CDS26360.1 - 0.0086 16.0 1.4 2.7 8.1 0.3 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CDS26360.1 - 0.026 13.5 0.0 30 3.4 0.0 3.8 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DREV PF05219.12 CDS26361.1 - 2.1e-66 223.7 0.1 1.3e-64 217.9 0.1 2.0 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 CDS26361.1 - 1.4e-11 44.5 0.0 1.8e-11 44.2 0.0 1.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS26361.1 - 1.5e-09 38.5 0.0 3.1e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS26361.1 - 1e-08 35.7 0.0 2.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS26361.1 - 1.5e-07 32.0 0.0 3.6e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS26361.1 - 5.9e-06 26.1 0.0 3.3e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CDS26361.1 - 0.087 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.20 CDS26361.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase VWA_3 PF13768.6 CDS26362.1 - 3.9e-15 56.1 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain TEA PF01285.18 CDS26363.1 - 1.9e-27 95.1 0.0 2.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain G-alpha PF00503.20 CDS26364.2 - 4.2e-48 164.3 7.7 1.9e-46 158.8 7.7 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS26364.2 - 1.9e-10 40.4 0.1 1.2e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS26364.2 - 0.079 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain WD40_3 PF15911.5 CDS26364.2 - 0.085 12.9 0.2 7.1 6.7 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat NYN_YacP PF05991.11 CDS26364.2 - 0.23 11.4 1.9 0.38 10.7 0.0 2.3 4 0 0 4 4 4 0 YacP-like NYN domain AAA_33 PF13671.6 CDS26365.1 - 3.7e-27 95.2 0.0 8.9e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SPRY PF00622.28 CDS26365.1 - 5.2e-12 45.9 0.9 5.2e-12 45.9 0.9 3.6 3 1 0 3 3 3 1 SPRY domain SAP PF02037.27 CDS26365.1 - 2.5e-08 33.5 0.4 4.5e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 SAP domain AAA_18 PF13238.6 CDS26365.1 - 0.00034 21.2 1.0 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CDS26365.1 - 0.00075 19.9 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDS26365.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin 6PF2K PF01591.18 CDS26365.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PARG_cat PF05028.14 CDS26366.1 - 6.1e-107 357.8 0.0 1.1e-106 357.0 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Img2 PF05046.14 CDS26366.1 - 3.8e-20 72.0 0.0 6.9e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CDS26366.1 - 0.0067 16.9 0.4 0.017 15.6 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 EF-hand_1 PF00036.32 CDS26367.1 - 2.4e-25 86.2 13.2 7.2e-08 31.5 0.5 4.4 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS26367.1 - 2.4e-23 82.3 8.9 3e-11 43.6 1.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS26367.1 - 2.1e-21 73.9 8.7 4.7e-05 23.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS26367.1 - 2.4e-19 67.9 8.5 1.8e-07 30.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS26367.1 - 2.7e-11 43.1 11.5 0.0012 18.7 0.2 4.3 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS26367.1 - 1.6e-06 28.4 3.1 0.00032 21.0 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS26367.1 - 0.0009 19.5 0.2 0.021 15.1 0.1 2.2 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CDS26367.1 - 0.0027 17.6 2.8 0.35 10.9 0.8 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 CDS26367.1 - 0.0034 16.0 0.2 0.011 14.3 0.2 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 CDS26367.1 - 0.0037 17.4 0.2 0.05 13.8 0.0 2.5 3 0 0 3 3 3 1 Dockerin type I domain Toprim_2 PF13155.6 CDS26367.1 - 0.14 12.5 0.1 1.7 9.1 0.0 2.3 1 1 1 2 2 2 0 Toprim-like GH-E PF14410.6 CDS26367.1 - 0.17 12.3 0.4 4.5 7.7 0.1 2.5 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EF-hand_10 PF14788.6 CDS26367.1 - 1 9.3 7.1 1.2 9.0 0.4 3.4 3 1 1 4 4 4 0 EF hand EF-hand_1 PF00036.32 CDS26368.1 - 1e-24 84.2 12.6 4.1e-07 29.1 0.0 6.7 7 0 0 7 7 7 5 EF hand EF-hand_7 PF13499.6 CDS26368.1 - 7.8e-23 80.7 4.0 1.6e-10 41.3 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS26368.1 - 2.7e-21 73.6 6.7 3.2e-06 26.6 0.0 6.1 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 CDS26368.1 - 3.6e-15 54.7 13.2 0.00047 19.5 0.0 6.4 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 CDS26368.1 - 4.7e-13 48.8 2.9 0.00065 19.5 0.0 4.7 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 CDS26368.1 - 0.0015 18.4 2.1 0.13 12.2 0.0 3.1 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDS26368.1 - 0.0019 18.5 0.0 1.2 9.5 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 CDS26368.1 - 0.0023 17.8 0.3 2.7 7.9 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_14 PF17959.1 CDS26368.1 - 0.082 13.3 0.1 9.4 6.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CDS26369.1 - 1.6e-26 89.8 4.8 4.5e-06 25.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS26369.1 - 2.4e-23 82.4 2.1 3.5e-12 46.6 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS26369.1 - 2.5e-22 76.8 4.3 6.7e-06 25.6 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS26369.1 - 1.8e-19 68.2 9.7 0.00051 19.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS26369.1 - 2.3e-12 46.6 5.8 0.00022 21.0 0.1 3.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 CDS26369.1 - 7.2e-05 22.6 0.2 0.36 10.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CDS26369.1 - 0.00045 20.5 0.1 0.0091 16.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS26369.1 - 0.00068 19.9 0.1 0.35 11.2 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS26369.1 - 0.033 14.2 1.4 6.2 6.8 0.5 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TGF_beta PF00019.20 CDS26370.1 - 3.5e-27 95.4 0.2 6.3e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 CDS26370.1 - 0.0033 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 TGF-beta propeptide EF-hand_7 PF13499.6 CDS26371.1 - 1.3e-19 70.4 6.9 1.7e-10 41.2 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS26371.1 - 2e-17 61.4 9.4 5.2e-05 22.5 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS26371.1 - 7e-17 59.9 9.0 2.1e-05 24.1 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS26371.1 - 3.1e-08 33.3 6.9 0.00011 21.9 0.2 3.6 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CDS26371.1 - 1.3e-07 31.5 1.9 0.0026 17.7 0.2 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS26371.1 - 1.6e-07 31.6 1.1 0.00053 20.3 0.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CDS26371.1 - 9.8e-07 28.0 11.0 0.00036 19.9 0.1 4.1 4 0 0 4 4 4 3 EF hand TerB PF05099.13 CDS26371.1 - 0.08 12.9 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB RA PF00788.23 CDS26373.1 - 2.2e-28 98.7 0.0 6.4e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DIL PF01843.19 CDS26373.1 - 6.8e-20 71.3 0.1 2.6e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 DIL domain PDZ PF00595.24 CDS26373.1 - 1.7e-05 25.1 0.0 0.0033 17.7 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDS26373.1 - 6.1e-05 22.8 0.1 0.00019 21.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDS26373.1 - 0.0076 16.6 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CDS26373.1 - 0.019 15.0 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Toxin-JAB1 PF15659.6 CDS26373.1 - 0.49 10.8 6.3 1.7 9.0 6.3 2.0 1 0 0 1 1 1 0 JAB-like toxin 1 zf-C4 PF00105.18 CDS26375.1 - 6.7e-22 77.7 10.3 1.1e-21 77.0 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FliT PF05400.13 CDS26376.2 - 0.023 15.5 0.4 0.038 14.8 0.4 1.4 1 0 0 1 1 1 0 Flagellar protein FliT SDA1 PF05285.12 CDS26377.1 - 4.7e-82 276.2 30.8 4.7e-82 276.2 30.8 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CDS26377.1 - 5.1e-12 45.9 1.0 1.3e-11 44.6 0.2 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Cnd1 PF12717.7 CDS26377.1 - 0.0052 16.8 0.2 0.019 15.0 0.2 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 CDS26377.1 - 0.029 14.1 0.3 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis zf-DBF PF07535.12 CDS26378.2 - 1.5e-14 53.8 1.0 3.2e-14 52.8 0.5 1.9 2 0 0 2 2 2 1 DBF zinc finger SH3_11 PF18103.1 CDS26380.1 - 0.044 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain HMG_box PF00505.19 CDS26381.1 - 1.2e-24 86.5 4.5 3e-24 85.2 4.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS26381.1 - 6.6e-09 36.2 2.3 1.7e-08 34.9 2.3 1.7 1 0 0 1 1 1 1 HMG-box domain CDC73_N PF16050.5 CDS26383.2 - 3.1e-67 227.0 4.3 8e-36 123.9 0.1 3.1 3 0 0 3 3 3 3 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 CDS26383.2 - 1.3e-42 145.2 0.9 3.5e-36 124.3 0.1 2.4 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family, C-terminal fn3 PF00041.21 CDS26384.1 - 1.5e-11 44.5 1.1 0.00013 22.3 0.1 3.5 3 0 0 3 3 3 3 Fibronectin type III domain ASH PF15780.5 CDS26384.1 - 0.17 12.1 2.4 0.25 11.6 0.5 2.3 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Exo_endo_phos_2 PF14529.6 CDS26385.1 - 7.1e-14 51.7 0.2 9.8e-14 51.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26385.1 - 0.046 13.2 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 CDS26386.1 - 5.1e-21 75.8 0.2 2.7e-20 73.5 0.2 2.4 1 0 0 1 1 1 1 SET domain Homeodomain PF00046.29 CDS26386.1 - 2.9e-20 71.9 5.1 9.9e-20 70.2 5.1 2.0 1 0 0 1 1 1 1 Homeodomain FYRC PF05965.14 CDS26386.1 - 3.5e-14 52.7 0.0 9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CDS26386.1 - 2.2e-08 33.8 0.0 5.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.29 CDS26386.1 - 5.2e-07 29.5 17.8 1.7e-05 24.6 4.1 8.7 7 2 1 8 8 8 3 PHD-finger Homeobox_KN PF05920.11 CDS26386.1 - 3.5 7.6 4.8 0.58 10.1 0.3 2.1 2 0 0 2 2 2 0 Homeobox KN domain DAGK_acc PF00609.19 CDS26387.1 - 1.8e-53 181.1 0.0 2.6e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDS26387.1 - 3.3e-22 78.4 0.0 5.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Insulin_TMD PF17870.1 CDS26388.1 - 0.0068 16.5 1.3 0.015 15.4 1.3 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment CNDH2_M PF16869.5 CDS26388.1 - 0.55 10.9 8.8 0.75 10.5 8.8 1.1 1 0 0 1 1 1 0 PF16858 C1_1 PF00130.22 CDS26389.1 - 1.1e-29 102.0 42.4 1.5e-11 44.0 13.2 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) RA PF00788.23 CDS26389.1 - 4e-09 37.0 0.1 0.0012 19.4 0.1 2.6 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain YfkB PF08756.10 CDS26389.1 - 0.024 14.4 2.3 6.7 6.5 0.0 3.4 3 0 0 3 3 3 0 YfkB-like domain C1_2 PF03107.16 CDS26389.1 - 1.1 9.6 39.6 0.13 12.6 2.6 3.9 4 0 0 4 4 4 0 C1 domain AAA PF00004.29 CDS26390.1 - 3.9e-38 130.9 0.0 7.6e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS26390.1 - 4.3e-11 42.4 0.0 1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CDS26390.1 - 5.5e-08 32.7 0.0 7.7e-07 29.0 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CDS26390.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDS26390.1 - 3.4e-05 23.9 0.1 0.00012 22.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS26390.1 - 0.0019 18.4 1.6 0.23 11.7 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CDS26390.1 - 0.002 18.5 1.2 0.016 15.6 1.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 CDS26390.1 - 0.0066 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CDS26390.1 - 0.0086 15.3 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CDS26390.1 - 0.011 15.2 0.2 0.034 13.5 0.2 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDS26390.1 - 0.012 15.7 0.3 0.14 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CDS26390.1 - 0.044 14.1 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDS26390.1 - 0.11 12.1 0.3 9.9 5.7 0.0 2.8 2 1 0 3 3 3 0 AAA domain zf_CCCH_4 PF18345.1 CDS26391.1 - 6.5e-15 54.6 32.3 1e-06 28.6 4.4 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 CDS26391.1 - 2e-12 46.7 33.7 1.3e-06 28.2 1.1 3.7 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDS26391.1 - 2.5e-08 34.6 20.2 3.6e-05 24.4 2.1 3.5 1 1 2 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 CDS26391.1 - 3.5e-08 33.0 28.5 0.0033 17.2 8.2 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDS26391.1 - 0.00017 21.7 18.8 0.041 14.1 1.6 3.4 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDS26391.1 - 0.041 14.4 3.6 0.041 14.4 3.6 3.9 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Calponin PF00402.18 CDS26392.1 - 7.5e-83 271.7 78.4 4.5e-13 48.6 3.5 7.4 7 0 0 7 7 7 7 Calponin family repeat CH PF00307.31 CDS26392.1 - 1.6e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CPP1-like PF11833.8 CDS26393.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Calponin PF00402.18 CDS26395.1 - 4.9e-77 253.1 73.5 1.1e-12 47.4 2.6 7.4 7 0 0 7 7 7 7 Calponin family repeat CH PF00307.31 CDS26395.1 - 1.4e-17 63.8 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CbiG_N PF11760.8 CDS26395.1 - 0.0076 16.2 9.3 2.9 7.9 0.1 5.0 4 1 1 5 5 5 2 Cobalamin synthesis G N-terminal TTC5_OB PF16669.5 CDS26395.1 - 0.12 12.0 0.1 92 2.8 0.0 4.5 3 2 3 6 6 6 0 Tetratricopeptide repeat protein 5 OB fold domain Porin_3 PF01459.22 CDS26396.1 - 1.1e-23 84.0 5.8 1.5e-23 83.7 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic porin DUF1642 PF07852.11 CDS26397.1 - 0.094 13.3 0.0 0.22 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) Ribosomal_S25 PF03297.15 CDS26398.1 - 2.7e-33 114.2 2.5 2.7e-33 114.2 2.5 1.5 2 0 0 2 2 2 1 S25 ribosomal protein Acetyltransf_3 PF13302.7 CDS26398.1 - 3e-13 50.6 0.0 1.7e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain 7tm_3 PF00003.22 CDS26399.1 - 6.3e-65 219.2 9.3 1.4e-64 218.0 9.3 1.6 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Ras PF00071.22 CDS26400.1 - 6.2e-34 116.9 0.1 7.1e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS26400.1 - 6.4e-15 55.4 0.0 9.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS26400.1 - 0.00025 20.6 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS26400.1 - 0.00028 20.9 0.0 0.00032 20.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS26400.1 - 0.001 18.6 0.2 0.48 9.9 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDS26400.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 CDS26400.1 - 0.032 13.6 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein BAG PF02179.16 CDS26401.1 - 2.3e-12 47.1 0.0 3.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 BAG domain WW PF00397.26 CDS26401.1 - 1.1e-10 41.4 0.3 2e-10 40.6 0.3 1.4 1 0 0 1 1 1 1 WW domain BIR PF00653.21 CDS26402.1 - 1.8e-21 76.6 0.2 2.6e-21 76.0 0.2 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CDS26402.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 C3HC zinc finger-like 7tm_1 PF00001.21 CDS26404.1 - 3.1e-49 167.7 0.4 3.8e-49 167.4 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 CDS26404.1 - 8e-05 22.1 6.6 0.00028 20.4 2.8 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.9 CDS26404.1 - 0.00023 20.6 4.3 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDS26404.1 - 0.00038 19.8 5.3 0.013 14.8 0.0 3.0 2 1 1 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srd PF10317.9 CDS26404.1 - 0.063 12.5 7.1 0.13 11.5 2.6 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Pkinase PF00069.25 CDS26407.1 - 8.5e-90 300.7 0.0 8.1e-50 169.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26407.1 - 1.9e-21 76.5 0.0 2.6e-12 46.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDS26407.1 - 0.00015 21.8 0.0 0.21 11.5 0.0 3.6 2 2 2 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS26407.1 - 0.027 13.3 0.0 6.6 5.4 0.0 3.1 4 0 0 4 4 4 0 Fungal protein kinase Kinase-like PF14531.6 CDS26407.1 - 0.073 12.4 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like WAC_Acf1_DNA_bd PF10537.9 CDS26408.1 - 1.9e-21 76.5 0.0 4.5e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 CDS26408.1 - 8.3e-13 48.4 0.0 1.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 CDS26408.1 - 1.4e-12 47.9 0.7 1.4e-11 44.8 0.7 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 CDS26408.1 - 0.014 14.9 0.3 0.031 13.8 0.3 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 CHAD PF05235.14 CDS26408.1 - 0.022 14.8 2.6 0.11 12.5 0.0 3.1 3 0 0 3 3 3 0 CHAD domain Syntaxin-6_N PF09177.11 CDS26408.1 - 0.1 13.1 0.3 0.47 11.0 0.3 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 CDS26408.1 - 0.21 11.6 1.9 0.45 10.5 0.9 2.1 2 0 0 2 2 2 0 Laminin Domain II PHD PF00628.29 CDS26408.1 - 0.54 10.2 10.7 0.13 12.2 1.1 3.3 3 0 0 3 3 3 0 PHD-finger CSN8_PSD8_EIF3K PF10075.9 CDS26409.1 - 4e-18 65.8 0.2 5.5e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Orthopox_A49R PF06489.11 CDS26409.1 - 0.035 14.4 0.2 0.05 13.8 0.2 1.2 1 0 0 1 1 1 0 Orthopoxvirus A49R protein DHR-2 PF06920.13 CDS26410.2 - 1.6e-119 400.0 0.0 5.7e-119 398.1 0.0 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 CDS26410.2 - 1.4e-42 145.8 0.0 3.8e-42 144.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins NeuB PF03102.14 CDS26410.2 - 0.00052 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 NeuB family PhoLip_ATPase_C PF16212.5 CDS26411.1 - 2.9e-60 204.1 29.2 2.9e-60 204.1 29.2 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDS26411.1 - 4.3e-19 68.0 4.1 1.8e-18 66.0 4.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDS26411.1 - 1.5e-10 41.8 1.4 7.1e-07 29.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDS26411.1 - 2e-10 40.6 0.2 6.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDS26411.1 - 0.0017 17.9 1.2 0.0065 16.0 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDS26411.1 - 0.0024 17.6 1.5 0.081 12.7 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3487 PF11990.8 CDS26411.1 - 0.84 9.5 0.0 0.84 9.5 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3487) Yippee-Mis18 PF03226.14 CDS26412.1 - 4.1e-15 55.9 0.0 7.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sec31 PF11549.8 CDS26412.1 - 0.13 12.2 0.6 0.29 11.1 0.6 1.6 1 0 0 1 1 1 0 Protein transport protein SEC31 EF-hand_1 PF00036.32 CDS26414.1 - 4e-40 132.4 10.1 2.9e-09 35.8 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS26414.1 - 8.4e-35 119.1 7.6 5.9e-17 61.9 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS26414.1 - 8.4e-32 106.4 7.7 7e-09 34.9 0.1 4.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CDS26414.1 - 2.2e-29 101.1 10.7 3.8e-16 58.7 0.4 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDS26414.1 - 1.3e-28 97.2 8.9 9.4e-07 28.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDS26414.1 - 1.3e-12 47.8 0.4 2e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS26414.1 - 4.4e-11 43.1 0.6 1.2e-05 25.6 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS26414.1 - 2.3e-10 40.4 1.2 0.00043 20.2 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CDS26414.1 - 1.9e-07 31.9 0.5 0.021 15.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 CDS26414.1 - 9.9e-06 25.4 1.9 0.0028 17.5 0.3 2.1 1 1 1 2 2 2 2 SurA N-terminal domain UPF0154 PF03672.13 CDS26414.1 - 4.9e-05 23.3 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 CDS26414.1 - 7.8e-05 22.7 0.5 0.025 14.6 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB SurA_N_2 PF13623.6 CDS26414.1 - 8.4e-05 22.5 1.9 0.0055 16.6 0.3 2.2 2 0 0 2 2 2 1 SurA N-terminal domain Dockerin_1 PF00404.18 CDS26414.1 - 0.00032 20.8 3.6 0.047 13.9 0.6 2.8 2 2 0 2 2 2 1 Dockerin type I domain EF-hand_14 PF17959.1 CDS26414.1 - 0.00093 19.5 1.1 0.33 11.3 0.1 2.6 1 1 0 2 2 2 1 EF-hand domain Syntaxin PF00804.25 CDS26414.1 - 0.0012 18.6 2.1 0.1 12.2 0.3 2.2 2 0 0 2 2 2 1 Syntaxin MotA_activ PF09114.10 CDS26414.1 - 0.0015 18.6 0.1 0.23 11.6 0.0 2.2 1 1 1 2 2 2 1 Transcription factor MotA, activation domain Caleosin PF05042.13 CDS26414.1 - 0.0053 16.7 3.2 3.7 7.4 0.2 3.5 1 1 3 4 4 4 1 Caleosin related protein Phage_TAC_12 PF12363.8 CDS26414.1 - 0.012 16.1 0.5 2.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DUF1456 PF07308.13 CDS26414.1 - 0.013 15.8 0.7 2.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) p25-alpha PF05517.12 CDS26414.1 - 0.041 14.1 2.4 0.56 10.4 0.3 2.4 1 1 2 3 3 3 0 p25-alpha DUF533 PF04391.12 CDS26414.1 - 0.042 13.4 2.6 8.8 5.9 0.1 3.2 1 1 2 4 4 4 0 Protein of unknown function (DUF533) Peptidase_M24 PF00557.24 CDS26414.1 - 0.054 13.2 0.1 4.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Metallopeptidase family M24 Mu-like_Pro PF10123.9 CDS26414.1 - 0.075 12.6 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF2059 PF09832.9 CDS26414.1 - 0.084 12.9 0.1 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) ApbA_C PF08546.11 CDS26414.1 - 0.096 12.9 0.4 7.2 6.8 0.1 2.2 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal YjbR PF04237.13 CDS26414.1 - 0.12 13.0 0.0 1.5 9.5 0.0 2.0 2 0 0 2 2 2 0 YjbR Toprim_4 PF13662.6 CDS26414.1 - 0.13 12.7 0.1 4.9 7.7 0.1 2.3 1 1 1 2 2 2 0 Toprim domain HHA PF05321.11 CDS26414.1 - 0.52 10.7 0.2 0.52 10.7 0.2 2.4 3 1 0 3 3 3 0 Haemolysin expression modulating protein ARL2_Bind_BART PF11527.8 CDS26414.1 - 0.66 10.1 10.4 21 5.2 8.5 2.9 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART VCBS PF13517.6 CDS26414.1 - 1.6 9.4 4.5 10 6.8 0.7 2.7 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PRKCSH-like PF12999.7 CDS26415.1 - 1.1e-39 136.0 3.0 1.8e-39 135.4 3.0 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CDS26415.1 - 7.8e-20 71.1 0.0 2.1e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CDS26415.1 - 1.2e-09 39.1 0.6 2.5e-09 38.0 0.6 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 CDS26415.1 - 0.00041 20.5 10.4 0.054 13.7 1.9 2.7 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A DUF4670 PF15709.5 CDS26415.1 - 0.5 9.6 9.5 0.74 9.1 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Homeodomain PF00046.29 CDS26416.1 - 9.7e-21 73.4 2.9 9.7e-21 73.4 2.9 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDS26416.1 - 0.01 15.7 1.9 0.038 13.9 0.1 2.8 3 0 0 3 3 3 0 Homeobox KN domain Sarcoglycan_1 PF04790.13 CDS26417.1 - 0.043 13.2 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein V-set PF07686.17 CDS26418.1 - 0.0016 18.6 0.0 1.8 8.8 0.0 2.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.6 CDS26418.1 - 0.012 16.2 0.1 0.26 11.9 0.1 2.7 2 1 0 2 2 2 0 Immunoglobulin domain ig PF00047.25 CDS26418.1 - 0.091 12.9 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 CDS26418.1 - 0.15 11.6 0.4 7.9 6.1 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain zf-C2H2 PF00096.26 CDS26419.1 - 3.4e-14 52.4 25.6 1.4e-05 25.2 3.0 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26419.1 - 7e-11 42.0 22.2 5.1e-08 33.0 1.5 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26419.1 - 9.6e-10 38.5 20.5 0.0041 17.8 3.0 4.0 3 1 1 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDS26419.1 - 1.6e-05 24.5 5.8 1.6e-05 24.5 5.8 3.8 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDS26419.1 - 0.022 15.0 13.6 0.73 10.2 2.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_7 PF15269.6 CDS26419.1 - 0.091 12.9 0.9 0.091 12.9 0.9 2.5 3 0 0 3 3 3 0 Zinc-finger Salp15 PF12115.8 CDS26419.1 - 0.27 11.7 8.6 0.11 12.9 6.2 1.6 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF3268 PF11672.8 CDS26419.1 - 0.3 11.4 4.9 0.26 11.6 2.6 1.9 2 0 0 2 2 2 0 zinc-finger-containing domain Zn_ribbon_SprT PF17283.2 CDS26419.1 - 0.54 10.2 8.8 0.18 11.7 1.5 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain YyzF PF14116.6 CDS26419.1 - 0.89 9.6 6.4 17 5.5 0.1 3.3 3 0 0 3 3 3 0 YyzF-like protein zf-C2H2_2 PF12756.7 CDS26419.1 - 2.7 8.4 14.0 50 4.3 13.9 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DRY_EERY PF09750.9 CDS26420.1 - 2.9e-34 118.3 0.1 2.9e-34 118.3 0.1 3.8 3 1 0 3 3 3 1 Alternative splicing regulator CDC27 PF09507.10 CDS26421.1 - 3e-11 43.4 38.4 4.4e-11 42.8 38.4 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Enolase_C PF00113.22 CDS26422.1 - 1.8e-132 441.0 0.0 2.3e-132 440.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDS26422.1 - 4.1e-53 179.0 0.0 9.5e-53 177.9 0.0 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDS26422.1 - 8.9e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDS26422.1 - 0.00099 18.3 0.1 0.0019 17.4 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HP_OMP PF01856.17 CDS26422.1 - 0.073 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Helicobacter outer membrane protein DUF956 PF06115.11 CDS26422.1 - 0.11 12.2 0.1 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF956) PTSIIB_sorb PF03830.15 CDS26422.1 - 0.13 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component P16-Arc PF04699.14 CDS26423.1 - 4.1e-39 134.4 0.1 5e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp13 PF08625.11 CDS26423.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain RhoGEF PF00621.20 CDS26424.2 - 5.4e-26 92.0 1.2 1.4e-25 90.6 1.2 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CDS26424.2 - 0.012 15.9 0.0 0.034 14.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain RRM_1 PF00076.22 CDS26425.1 - 5.2e-19 67.8 0.0 8.3e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS26425.1 - 7.9e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDS26425.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YccV-like PF08755.11 CDS26426.1 - 3.2e-20 72.4 0.0 4.5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like CPSase_L_D2 PF02786.17 CDS26427.1 - 1.3e-68 230.6 0.0 1.9e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDS26427.1 - 6.1e-44 149.1 0.0 1.1e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDS26427.1 - 9e-29 99.7 0.0 7e-28 96.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CDS26427.1 - 2.6e-17 62.4 0.3 5.2e-17 61.4 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDS26427.1 - 9.8e-12 44.5 0.0 9.7e-07 28.5 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CDS26427.1 - 5.4e-06 26.1 0.0 1.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 CDS26427.1 - 1.5e-05 25.7 0.0 0.019 15.7 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.22 CDS26427.1 - 0.0002 21.0 0.0 0.00076 19.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 CDS26427.1 - 0.00024 20.4 0.2 0.14 11.4 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion PCC_BT PF18140.1 CDS26427.1 - 0.007 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain RnfC_N PF13375.6 CDS26427.1 - 0.032 14.2 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 CDS26427.1 - 0.053 13.6 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_5 PF13549.6 CDS26427.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 CDS26427.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain INCENP_ARK-bind PF03941.15 CDS26428.2 - 0.0098 15.8 0.1 0.037 14.0 0.1 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF2514 PF10721.9 CDS26428.2 - 0.018 15.1 9.6 0.037 14.1 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pkinase PF00069.25 CDS26429.1 - 0.00018 21.0 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26429.1 - 0.0079 15.5 0.0 0.0088 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kunitz_BPTI PF00014.23 CDS26432.1 - 1.9e-17 63.2 3.9 2.5e-17 62.9 3.9 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-C2H2 PF00096.26 CDS26433.1 - 6.5e-09 35.8 27.3 2.2e-05 24.7 4.1 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS26433.1 - 4.2e-07 30.2 22.8 0.0087 16.8 2.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS26433.1 - 0.0051 17.2 0.8 0.0051 17.2 0.8 4.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CDS26433.1 - 0.041 14.5 8.4 2.1 9.1 0.4 3.0 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CDS26433.1 - 0.14 12.6 12.3 0.21 12.0 0.2 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDS26433.1 - 0.28 11.6 12.8 0.77 10.1 0.3 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CDS26433.1 - 0.44 10.6 8.7 0.21 11.6 1.5 2.7 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 CDS26433.1 - 0.49 10.5 14.6 0.73 9.9 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS26433.1 - 0.76 10.1 11.6 2.7 8.4 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 CDS26433.1 - 1.3 8.7 8.6 3 7.5 0.1 2.7 2 1 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 CDS26434.1 - 4.7e-09 36.2 29.3 1.2e-05 25.5 4.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS26434.1 - 7.2e-05 23.3 26.8 0.005 17.6 2.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS26434.1 - 0.00054 20.3 1.5 0.00054 20.3 1.5 4.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 CDS26434.1 - 0.13 12.7 17.5 0.23 11.9 1.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CCHC_2 PF13696.6 CDS26434.1 - 0.19 11.6 4.6 0.2 11.5 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_6 PF13912.6 CDS26434.1 - 2.4 8.3 20.8 0.34 11.0 2.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Laminin_EGF PF00053.24 CDS26434.1 - 3.6 7.8 10.2 12 6.1 5.9 2.6 2 0 0 2 2 2 0 Laminin EGF domain zf-C2H2_2 PF12756.7 CDS26434.1 - 4.3 7.7 13.9 2.2 8.7 0.8 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDS26434.1 - 5.4 7.4 17.3 7.3 7.0 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RPA_C PF08784.11 CDS26436.1 - 2.6 8.8 7.0 5.4 7.7 1.7 3.4 2 2 0 2 2 2 0 Replication protein A C terminal Nore1-SARAH PF16517.5 CDS26438.1 - 2.4e-12 46.6 1.3 4.3e-12 45.7 1.3 1.4 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RA PF00788.23 CDS26438.1 - 4.8e-11 43.2 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Memo PF01875.17 CDS26438.1 - 0.16 11.1 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 Memo-like protein Pkinase PF00069.25 CDS26439.1 - 1.3e-05 24.7 0.0 0.00041 19.8 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26439.1 - 2.6e-05 23.7 0.0 0.0028 17.0 0.1 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Activin_recp PF01064.23 CDS26439.1 - 0.00097 20.2 1.5 0.00097 20.2 1.5 3.6 3 0 0 3 3 3 1 Activin types I and II receptor domain Ran_BP1 PF00638.18 CDS26440.1 - 4.2e-99 327.3 1.9 8.3e-37 126.2 0.1 4.5 4 0 0 4 4 4 4 RanBP1 domain WH1 PF00568.23 CDS26440.1 - 6.7e-08 32.4 0.0 0.006 16.5 0.0 3.5 3 0 0 3 3 3 2 WH1 domain FPP PF05911.11 CDS26440.1 - 9.3 4.3 8.5 1.1 7.4 2.2 2.2 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DFP PF04127.15 CDS26441.1 - 9e-12 45.2 0.0 9.4e-07 28.8 0.0 2.9 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein GLTSCR1 PF15249.6 CDS26442.1 - 7.9e-07 29.5 0.1 1.6e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein IBN_N PF03810.19 CDS26443.1 - 2e-10 40.4 0.0 1.4e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CDS26443.1 - 2.5e-06 26.6 0.1 6.3e-05 22.0 0.0 2.6 2 0 0 2 2 2 1 Cse1 HEAT PF02985.22 CDS26443.1 - 0.19 12.1 6.6 3.3 8.2 0.1 5.2 5 0 0 5 5 5 0 HEAT repeat Linker_histone PF00538.19 CDS26444.1 - 2.8e-27 94.9 0.6 2.8e-27 94.9 0.6 2.1 3 0 0 3 3 3 1 linker histone H1 and H5 family ASH PF15780.5 CDS26445.1 - 2.6e-09 37.2 0.9 0.48 10.7 0.0 7.2 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CDS26445.1 - 0.0003 20.6 1.5 0.62 9.9 0.1 4.1 5 0 0 5 5 5 2 MSP (Major sperm protein) domain PapD-like PF14874.6 CDS26445.1 - 0.077 13.2 0.0 1.9 8.7 0.0 3.2 2 0 0 2 2 2 0 Flagellar-associated PapD-like TMEM131_like PF12371.8 CDS26445.1 - 0.1 12.8 5.4 0.72 10.2 0.1 4.6 5 0 0 5 5 5 0 Transmembrane protein 131-like DUF1573 PF07610.11 CDS26445.1 - 0.11 12.5 0.8 5.7 7.0 0.0 4.1 5 1 0 5 5 5 0 Protein of unknown function (DUF1573) Cyt-b5 PF00173.28 CDS26446.1 - 6.7e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycolytic PF00274.19 CDS26447.1 - 3.5e-183 608.1 0.0 4e-183 607.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Pkinase PF00069.25 CDS26449.1 - 9.9e-12 44.8 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PX PF00787.24 CDS26449.1 - 4.8e-10 39.4 0.4 9.8e-10 38.4 0.4 1.5 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 CDS26449.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase MIT PF04212.18 CDS26449.1 - 0.017 15.2 0.4 0.034 14.2 0.4 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Kinase-like PF14531.6 CDS26449.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ubie_methyltran PF01209.18 CDS26450.1 - 3e-89 298.4 0.0 3.6e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDS26450.1 - 5.7e-18 65.4 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS26450.1 - 2.7e-17 63.2 0.0 4.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS26450.1 - 3.4e-14 52.9 0.0 6.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS26450.1 - 1.4e-09 38.6 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS26450.1 - 2.4e-09 37.3 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDS26450.1 - 0.0038 17.1 0.0 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 CDS26450.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 CDS26450.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FAD_binding_1 PF00667.20 CDS26451.1 - 1.5e-27 96.6 0.0 2.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CDS26451.1 - 8.8e-11 42.4 0.0 1.1e-08 35.6 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain EzrA PF06160.12 CDS26452.1 - 0.0025 16.1 12.6 0.0025 16.1 12.6 6.6 3 1 0 5 5 5 4 Septation ring formation regulator, EzrA Ion_trans PF00520.31 CDS26453.1 - 2.3e-34 118.7 12.9 3.2e-34 118.3 12.9 1.2 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.7 CDS26453.1 - 1.7e-13 50.7 0.0 4.1e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain Ion_trans_2 PF07885.16 CDS26453.1 - 3.1e-10 39.9 0.5 3.1e-10 39.9 0.5 2.3 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 CDS26453.1 - 3e-08 33.6 0.0 6.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_3 PF08447.12 CDS26453.1 - 0.00073 19.8 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold TPD52 PF04201.15 CDS26453.1 - 0.035 13.7 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 Tumour protein D52 family PAS PF00989.25 CDS26453.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 PAS fold IMUP PF15761.5 CDS26453.1 - 0.37 11.5 6.8 1.1 10.0 6.8 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein HTH_48 PF17906.1 CDS26455.1 - 1.3e-06 28.4 1.8 1.7e-05 24.8 1.8 2.2 1 1 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDS26455.1 - 0.00011 22.0 1.9 0.00011 22.0 1.9 2.9 2 2 1 3 3 3 1 Transposase (partial DDE domain) HA2 PF04408.23 CDS26456.1 - 1.2e-20 73.8 0.0 1.2e-20 73.8 0.0 4.1 5 0 0 5 5 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDS26456.1 - 4.4e-14 52.6 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDS26456.1 - 4.7e-14 52.7 0.0 1.3e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDS26456.1 - 4.6e-06 27.0 0.1 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDS26456.1 - 2.5e-05 24.1 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDS26456.1 - 8.5e-05 22.4 0.6 0.00022 21.0 0.2 1.9 2 1 0 2 2 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDS26456.1 - 0.00053 20.4 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDS26456.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 CDS26456.1 - 0.0078 16.4 1.9 0.5 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CDS26456.1 - 0.0084 15.4 0.0 0.03 13.6 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDS26456.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRP54 PF00448.22 CDS26456.1 - 0.015 14.9 0.1 0.042 13.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CDS26456.1 - 0.02 15.4 1.0 0.12 12.9 0.1 2.8 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CDS26456.1 - 0.028 14.9 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 CDS26456.1 - 0.031 14.3 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 CDS26456.1 - 0.066 13.2 0.2 0.73 9.9 0.2 2.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CDS26456.1 - 0.072 13.1 0.2 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CDS26456.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DSS1_SEM1 PF05160.13 CDS26457.1 - 1.2e-10 41.3 12.7 1.3e-10 41.2 12.7 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 CDS26457.1 - 0.00033 20.5 2.9 0.00038 20.3 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) Sugar_tr PF00083.24 CDS26458.1 - 2.7e-63 214.4 28.2 2.5e-54 184.9 16.9 3.3 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CDS26458.1 - 8.2e-22 77.6 45.4 1.3e-21 76.9 34.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.28 CDS26459.1 - 2.2e-13 49.6 0.0 3.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS26459.1 - 6.5e-12 45.1 0.1 9.8e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS26459.1 - 2.4e-08 33.5 0.1 3.4e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain DSPc PF00782.20 CDS26461.1 - 6.7e-14 51.8 0.1 1.5e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CDS26461.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Pkinase PF00069.25 CDS26462.1 - 2.5e-73 246.7 0.0 3.3e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26462.1 - 1.5e-37 129.3 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CDS26462.1 - 4.5e-14 52.8 0.1 1e-13 51.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CDS26462.1 - 1.2e-09 37.9 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CDS26462.1 - 0.046 14.1 3.3 0.17 12.3 2.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Haspin_kinase PF12330.8 CDS26462.1 - 0.06 12.3 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 CDS26462.1 - 0.33 11.7 1.2 0.46 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein kinase C terminal domain Glutaredoxin PF00462.24 CDS26463.1 - 9.7e-13 48.1 0.0 3.7e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Glutaredoxin Branch PF02485.21 CDS26464.1 - 3.4e-31 108.6 0.1 6.5e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RVT_1 PF00078.27 CDS26464.1 - 1.9e-09 37.4 0.1 3.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDS26464.1 - 6.8e-06 25.9 0.8 2e-05 24.4 0.4 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase FAM183 PF14886.6 CDS26465.1 - 9.9e-05 23.0 2.0 0.00039 21.1 2.0 2.0 1 1 0 1 1 1 1 FAM183A and FAM183B related DUF4541 PF15074.6 CDS26465.1 - 0.011 16.4 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) RabGAP-TBC PF00566.18 CDS26466.1 - 7.9e-42 143.3 3.3 1.2e-41 142.8 3.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nbl1_Borealin_N PF10444.9 CDS26466.1 - 0.059 13.0 0.3 0.36 10.5 0.0 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal CLAMP PF14769.6 CDS26466.1 - 0.071 13.6 0.4 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Fib_alpha PF08702.10 CDS26466.1 - 0.23 11.6 1.4 12 6.1 0.0 3.2 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Ig_3 PF13927.6 CDS26467.1 - 6e-08 33.2 0.0 2.7e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDS26467.1 - 3.8e-05 23.7 0.0 0.0006 19.8 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS26467.1 - 0.00085 19.6 0.3 0.022 15.1 0.1 2.7 2 1 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CDS26467.1 - 0.0039 17.3 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Cyclin_N PF00134.23 CDS26468.1 - 8.3e-05 22.3 1.8 0.00064 19.5 0.2 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 CDS26468.1 - 0.0048 17.3 0.5 0.008 16.5 0.5 1.4 1 0 0 1 1 1 1 Cyclin Pox_A_type_inc PF04508.12 CDS26469.2 - 0.00098 18.9 15.2 0.24 11.3 0.7 5.5 5 0 0 5 5 5 3 Viral A-type inclusion protein repeat TSC22 PF01166.18 CDS26469.2 - 0.18 12.1 0.2 0.18 12.1 0.2 7.4 7 0 0 7 7 7 0 TSC-22/dip/bun family Snurportin1 PF11538.8 CDS26471.1 - 0.0005 20.2 5.8 0.0037 17.4 3.1 2.5 2 0 0 2 2 2 1 Snurportin1 SMI1_KNR4 PF09346.10 CDS26471.1 - 0.049 14.0 0.2 0.25 11.7 0.0 2.2 3 0 0 3 3 3 0 SMI1 / KNR4 family (SUKH-1) CaKB PF03185.15 CDS26472.1 - 2.9e-15 56.5 4.0 4e-15 56.0 4.0 1.2 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit zf-C2HE PF16278.5 CDS26472.1 - 0.7 10.4 4.4 0.37 11.3 0.9 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SAND PF01342.21 CDS26475.2 - 0.13 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 SAND domain COPIIcoated_ERV PF07970.12 CDS26476.1 - 1.6e-75 253.8 0.0 2.2e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDS26476.1 - 3.6e-29 100.9 0.2 6.3e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UPF0506 PF11703.8 CDS26477.1 - 0.007 16.7 17.0 0.016 15.6 17.0 1.6 1 0 0 1 1 1 1 UPF0506 Toxin_19 PF08088.12 CDS26477.1 - 0.02 15.0 4.6 0.02 15.0 4.6 2.5 1 1 1 2 2 2 0 Conotoxin I-superfamily Dickkopf_N PF04706.12 CDS26477.1 - 0.24 11.9 21.0 0.49 10.9 17.3 2.5 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region WAP PF00095.21 CDS26477.1 - 8.4 6.9 24.6 5.2 7.5 15.8 2.7 1 1 1 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' RFX_DNA_binding PF02257.15 CDS26478.2 - 4.9e-29 100.8 0.2 8.5e-29 100.0 0.2 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 CDS26478.2 - 0.034 14.1 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pox_D5 PF03288.16 CDS26478.2 - 0.065 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like fn3 PF00041.21 CDS26480.1 - 5.3e-09 36.3 0.3 0.00048 20.4 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain DAG1 PF05454.11 CDS26480.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Adeno_E3 PF06040.11 CDS26480.1 - 0.087 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein Amnionless PF14828.6 CDS26480.1 - 0.14 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Amnionless Homeodomain PF00046.29 CDS26481.1 - 9.6e-20 70.2 1.9 2e-19 69.2 1.9 1.6 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 CDS26481.1 - 4e-15 55.8 19.9 1.2e-09 38.2 8.4 2.5 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CDS26481.1 - 8.1e-06 25.6 0.1 2.1e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain ATG7_N PF16420.5 CDS26482.1 - 2.1e-79 267.3 0.1 3e-79 266.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CDS26482.1 - 1.4e-43 149.0 0.0 2.5e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CDS26482.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CDS26482.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 CDS26482.1 - 0.098 12.0 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 CDS26482.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Y_phosphatase PF00102.27 CDS26483.1 - 4.1e-54 183.6 0.0 8.2e-54 182.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDS26483.1 - 0.023 14.5 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ORC5_C PF14630.6 CDS26484.1 - 6.5e-50 170.3 0.0 8.5e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CDS26484.1 - 1.8e-06 28.4 0.0 8.7e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CDS26484.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS26484.1 - 0.0036 17.6 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDS26484.1 - 0.0089 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDS26484.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CDS26484.1 - 0.033 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CDS26484.1 - 0.036 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CDS26484.1 - 0.039 13.7 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDS26484.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDS26484.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CDS26484.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 CDS26484.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CDS26484.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDS26484.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pet100 PF09803.9 CDS26486.1 - 5e-07 30.2 0.0 5.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Pet100 Pyr_redox_2 PF07992.14 CDS26487.1 - 4.5e-55 187.0 0.3 1.4e-53 182.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDS26487.1 - 6.2e-28 97.3 0.0 1.3e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDS26487.1 - 7.1e-17 61.7 0.1 9.6e-14 51.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 CDS26487.1 - 2.7e-15 56.3 0.0 6.2e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Pyr_redox_3 PF13738.6 CDS26487.1 - 1.7e-13 50.6 1.0 5.5e-11 42.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDS26487.1 - 4.5e-06 26.0 2.3 0.00018 20.7 0.8 2.6 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CDS26487.1 - 0.00036 19.8 0.4 0.00083 18.7 0.4 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CDS26487.1 - 0.00053 19.2 0.3 0.00053 19.2 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDS26487.1 - 0.0019 17.3 0.2 0.0033 16.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CDS26487.1 - 0.0031 16.3 0.5 0.0069 15.1 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 CDS26487.1 - 0.0033 16.6 0.3 1.4 8.0 0.0 3.5 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thioredoxin_2 PF13098.6 CDS26487.1 - 0.0062 17.0 0.0 0.022 15.2 0.0 1.9 2 0 0 2 2 1 1 Thioredoxin-like domain FAD_oxidored PF12831.7 CDS26487.1 - 0.01 15.2 2.5 0.016 14.6 2.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDS26487.1 - 0.013 14.8 0.0 0.32 10.2 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CDS26487.1 - 0.04 14.2 4.8 0.052 13.8 1.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF836 PF05768.14 CDS26487.1 - 0.04 14.3 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DAO PF01266.24 CDS26487.1 - 0.044 13.4 2.0 0.073 12.6 1.2 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ephrin PF00812.17 CDS26488.1 - 2.6e-08 34.0 0.7 5.3e-08 33.0 0.7 1.6 1 1 0 1 1 1 1 Ephrin Innate_immun PF12782.7 CDS26488.1 - 4.4 6.7 5.3 7.2 6.0 5.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family 7tm_1 PF00001.21 CDS26489.1 - 1.5e-12 47.4 8.3 2e-12 47.0 8.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS26489.1 - 3.2e-05 23.4 11.3 4.3e-05 23.0 9.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM154 PF15102.6 CDS26489.1 - 0.018 14.9 2.1 0.02 14.8 0.5 1.9 1 1 1 2 2 2 0 TMEM154 protein family 7TM_GPCR_Srx PF10328.9 CDS26489.1 - 0.25 10.9 17.1 0.045 13.4 8.2 2.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4834 PF16118.5 CDS26489.1 - 3.8 8.5 6.2 0.54 11.3 1.4 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) PP2C PF00481.21 CDS26491.1 - 1.2e-69 234.9 0.1 5e-55 186.9 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDS26491.1 - 0.00041 20.1 0.0 0.001 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Fe-S_biosyn PF01521.20 CDS26492.1 - 1.9e-19 69.9 0.0 2.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Cys_rich_FGFR PF00839.17 CDS26493.1 - 9e-105 342.8 61.8 6.1e-16 58.3 0.1 14.5 15 0 0 15 15 15 13 Cysteine rich repeat Pkinase PF00069.25 CDS26494.1 - 5.8e-44 150.4 0.1 9.7e-44 149.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26494.1 - 2.2e-29 102.5 0.1 4e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PUB PF09409.10 CDS26494.1 - 1.6e-11 44.0 3.0 6.2e-11 42.1 0.4 2.5 2 0 0 2 2 2 1 PUB domain Kinase-like PF14531.6 CDS26494.1 - 1e-05 25.1 0.1 7.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PHD PF00628.29 CDS26494.1 - 0.00026 20.8 9.0 0.00051 19.9 9.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDS26494.1 - 0.053 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Haspin_kinase PF12330.8 CDS26494.1 - 0.065 12.2 0.1 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain UBX PF00789.20 CDS26494.1 - 0.11 12.8 0.0 0.9 9.8 0.0 2.7 2 1 0 2 2 2 0 UBX domain SH2 PF00017.24 CDS26495.1 - 3.6e-16 59.0 0.0 6.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 SH2 domain FOG_N PF15888.5 CDS26495.1 - 0.0065 16.8 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Folded gastrulation N-terminus Septin PF00735.18 CDS26499.1 - 5.3e-119 396.7 0.2 7.2e-119 396.2 0.2 1.1 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CDS26499.1 - 4.8e-08 33.1 0.0 5.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CDS26499.1 - 2.3e-07 30.9 0.0 5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS26499.1 - 0.00016 21.3 0.1 0.25 10.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDS26499.1 - 0.00021 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CDS26499.1 - 0.00025 21.2 0.0 0.34 11.0 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 CDS26499.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CDS26499.1 - 0.02 15.2 0.1 0.077 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDS26499.1 - 0.02 15.3 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CDS26499.1 - 0.033 14.7 0.0 0.081 13.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDS26499.1 - 0.04 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain THOC7 PF05615.13 CDS26499.1 - 0.05 13.9 0.8 0.23 11.7 0.2 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Ras PF00071.22 CDS26499.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras family NACHT PF05729.12 CDS26499.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Phospholip_B PF04916.13 CDS26500.1 - 2.3e-143 478.6 0.1 2.6e-143 478.4 0.1 1.0 1 0 0 1 1 1 1 Phospholipase B GNAT_acetyltr_2 PF13718.6 CDS26501.2 - 2.6e-93 311.6 0.0 3.3e-62 209.9 0.0 2.4 1 1 1 2 2 2 2 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CDS26501.2 - 1.6e-53 181.2 0.0 4.3e-53 179.8 0.0 1.8 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 CDS26501.2 - 8.6e-33 114.0 0.7 8.6e-33 114.0 0.7 3.1 3 1 0 3 3 3 1 Possible tRNA binding domain DUF1726 PF08351.11 CDS26501.2 - 1.4e-32 111.5 0.1 3.8e-32 110.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) zf-C2H2 PF00096.26 CDS26501.2 - 4.5e-27 93.0 52.0 5.7e-06 26.5 0.1 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26501.2 - 3.1e-25 87.4 44.1 0.00013 22.3 2.1 7.5 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26501.2 - 9e-19 66.6 44.5 0.007 17.1 1.9 7.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS26501.2 - 6.5e-07 29.5 31.8 0.38 11.1 3.1 6.6 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS26501.2 - 1.2e-06 28.3 36.8 0.012 15.6 5.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 CDS26501.2 - 2.2e-05 24.7 25.7 0.17 12.4 0.6 6.6 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDS26501.2 - 0.017 15.4 30.9 0.4 11.0 9.1 4.4 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Acetyltransf_7 PF13508.7 CDS26501.2 - 0.041 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GAGA PF09237.11 CDS26501.2 - 0.085 12.7 10.7 14 5.6 0.2 5.1 1 1 3 5 5 5 0 GAGA factor Acetyltransf_1 PF00583.25 CDS26501.2 - 0.18 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Rad50_zn_hook PF04423.14 CDS26501.2 - 0.18 11.6 2.7 0.66 9.9 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif Zn_Tnp_IS1595 PF12760.7 CDS26501.2 - 0.35 10.9 18.8 0.33 11.0 0.7 3.9 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zf-C2H2_9 PF16293.5 CDS26501.2 - 0.4 10.5 11.3 6.9 6.6 0.0 4.9 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 CDS26501.2 - 0.55 10.3 21.6 0.6 10.1 3.4 4.8 3 1 2 5 5 5 0 Adenylate kinase, active site lid CpXC PF14353.6 CDS26501.2 - 1.5 8.9 11.9 4.6 7.3 1.3 3.6 2 2 1 3 3 3 0 CpXC protein zinc_ribbon_15 PF17032.5 CDS26501.2 - 3 8.6 15.5 6.5 7.6 0.3 3.9 2 1 2 4 4 3 0 zinc-ribbon family FYVE PF01363.21 CDS26501.2 - 9.1 6.5 26.3 23 5.2 8.0 4.1 1 1 2 3 3 3 0 FYVE zinc finger SNF PF00209.18 CDS26502.2 - 8.6e-191 635.2 44.7 1e-190 634.9 44.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Transposase_1 PF01359.18 CDS26503.1 - 0.0017 18.2 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) SNF PF00209.18 CDS26504.1 - 2.7e-184 613.7 30.6 3.8e-184 613.2 30.6 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family ExbD PF02472.16 CDS26505.2 - 0.032 14.4 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Nairovirus_M PF07948.11 CDS26506.1 - 0.074 11.3 0.0 0.085 11.1 0.0 1.0 1 0 0 1 1 1 0 Nairovirus M polyprotein-like PBC PF03792.13 CDS26508.1 - 2.8e-79 265.3 0.4 4.1e-79 264.8 0.4 1.2 1 0 0 1 1 1 1 PBC domain Homeodomain PF00046.29 CDS26508.1 - 1.3e-19 69.8 0.5 1.3e-19 69.8 0.5 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDS26508.1 - 5.6e-16 58.2 0.0 1.8e-15 56.5 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CDS26508.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.7 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 CDS26508.1 - 0.0032 17.5 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix Nucleoporin_FG2 PF15967.5 CDS26508.1 - 0.0047 15.5 0.2 0.0072 14.9 0.2 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeated region DUF932 PF06067.11 CDS26508.1 - 0.039 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF932) HTH_11 PF08279.12 CDS26508.1 - 0.062 13.3 0.3 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.6 CDS26508.1 - 0.13 12.1 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain NUC130_3NT PF08158.12 CDS26508.1 - 0.44 10.9 2.7 20 5.6 0.1 3.6 4 0 0 4 4 4 0 NUC130/3NT domain SURF6 PF04935.12 CDS26509.1 - 3e-19 69.6 29.1 3.4e-19 69.4 29.1 1.0 1 0 0 1 1 1 1 Surfeit locus protein 6 LIFR_D2 PF17971.1 CDS26509.1 - 0.046 13.9 0.2 0.057 13.6 0.2 1.1 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor D2 domain Macoilin PF09726.9 CDS26509.1 - 0.047 12.3 17.4 0.056 12.0 17.4 1.0 1 0 0 1 1 1 0 Macoilin family Asp_Arg_Hydrox PF05118.15 CDS26509.1 - 0.052 13.4 0.6 0.066 13.0 0.6 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase SpoIID PF08486.10 CDS26509.1 - 0.11 13.1 0.5 0.14 12.8 0.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein HMG_CoA_synt_C PF08540.10 CDS26509.1 - 0.34 10.5 4.1 0.24 11.0 2.4 1.5 1 1 1 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal U3_assoc_6 PF08640.11 CDS26509.1 - 2.1 8.5 13.3 11 6.2 11.0 2.1 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Atg14 PF10186.9 CDS26509.1 - 4.9 6.2 17.7 6.3 5.8 17.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chordopox_G3 PF06129.12 CDS26511.1 - 0.069 13.9 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Annexin PF00191.20 CDS26512.1 - 1.2e-49 166.2 15.1 8.9e-16 57.7 0.6 4.2 4 0 0 4 4 4 4 Annexin MqsA_antitoxin PF15731.5 CDS26512.1 - 0.028 14.5 0.1 0.075 13.1 0.1 1.7 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Annexin PF00191.20 CDS26513.1 - 1.4e-54 182.0 12.2 1.7e-16 60.0 0.2 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 CDS26513.1 - 0.012 16.1 1.5 1.9 9.0 0.1 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1722 PF08349.11 CDS26513.1 - 0.49 10.7 4.3 10 6.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) SLATT_5 PF18160.1 CDS26513.1 - 0.97 8.7 6.8 0.52 9.6 0.2 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 RhoGEF PF00621.20 CDS26516.1 - 5.8e-33 114.7 2.8 5.8e-33 114.7 2.8 2.0 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.6 CDS26516.1 - 4.8e-09 35.9 0.1 8.9e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS26516.1 - 8.9e-09 34.8 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH_16 PF17838.1 CDS26516.1 - 0.024 14.5 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 PH domain Strabismus PF06638.11 CDS26517.1 - 7.2e-108 361.4 0.7 5.8e-61 206.7 4.1 4.2 3 2 0 3 3 3 3 Strabismus protein GspH PF12019.8 CDS26517.1 - 0.054 13.9 0.1 0.19 12.2 0.1 2.0 1 0 0 1 1 1 0 Type II transport protein GspH DUF4131 PF13567.6 CDS26517.1 - 2.2 7.9 6.1 2.3 7.8 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Memo PF01875.17 CDS26518.1 - 4.8e-64 216.1 0.0 3.3e-61 206.8 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein TPR_14 PF13428.6 CDS26519.1 - 1.1e-15 56.9 18.9 0.1 13.5 0.1 12.3 9 4 5 14 14 13 3 Tetratricopeptide repeat Suf PF05843.14 CDS26519.1 - 2.2e-12 47.6 11.4 4.4e-06 26.9 3.1 5.5 4 2 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 CDS26519.1 - 1.8e-11 43.8 10.6 0.00026 20.3 0.9 4.9 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDS26519.1 - 5.5e-07 30.0 10.6 1.1 9.8 0.0 8.1 8 1 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CDS26519.1 - 7.8e-07 28.5 18.9 0.0031 16.7 0.8 6.6 2 2 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 CDS26519.1 - 1.3e-06 28.2 8.6 2.3 8.7 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS26519.1 - 1.2e-05 25.1 18.3 2.8 8.3 0.1 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDS26519.1 - 7e-05 22.8 15.3 6.5 6.8 0.1 7.7 9 0 0 9 9 9 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CDS26519.1 - 0.0093 16.2 12.0 29 5.0 0.9 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 CDS26519.1 - 0.012 15.3 12.8 0.019 14.7 0.7 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 CDS26519.1 - 0.013 15.9 13.5 10 6.7 0.1 7.0 10 0 0 10 10 9 0 Tetratricopeptide repeat PPR PF01535.20 CDS26519.1 - 0.018 15.3 2.2 12 6.4 0.0 5.2 6 0 0 6 6 5 0 PPR repeat HhH-GPD PF00730.25 CDS26519.1 - 0.02 15.4 0.1 0.09 13.2 0.1 2.2 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein SNAP PF14938.6 CDS26519.1 - 0.52 9.7 9.4 0.14 11.5 0.5 4.0 3 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CDS26519.1 - 3.9 8.3 19.1 46 5.0 0.1 7.8 10 0 0 10 10 7 0 Tetratricopeptide repeat Tektin PF03148.14 CDS26520.1 - 6.1e-94 314.9 37.6 6.9e-94 314.7 37.6 1.0 1 0 0 1 1 1 1 Tektin family PUB PF09409.10 CDS26520.1 - 0.00077 19.4 0.2 0.0025 17.7 0.2 1.8 1 0 0 1 1 1 1 PUB domain RecX PF02631.16 CDS26520.1 - 0.022 15.2 2.7 0.025 15.0 0.2 2.3 2 0 0 2 2 2 0 RecX family PI3K_P85_iSH2 PF16454.5 CDS26520.1 - 0.032 13.8 24.2 0.052 13.2 3.6 3.5 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 CDS26520.1 - 1.1 9.3 20.0 0.054 13.5 4.9 4.0 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) V-ATPase_H_C PF11698.8 CDS26520.1 - 1.1 9.4 6.9 0.26 11.4 0.4 2.7 2 1 1 3 3 3 0 V-ATPase subunit H DUF948 PF06103.11 CDS26520.1 - 6.7 7.0 6.4 3.1 8.1 0.8 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Alpha_kinase PF02816.18 CDS26521.1 - 1.7e-55 188.0 0.0 2.3e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 CDS26521.1 - 0.15 12.8 6.8 14 6.5 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat Forkhead PF00250.18 CDS26528.1 - 1.7e-37 127.5 0.2 4.8e-37 126.1 0.2 1.8 1 0 0 1 1 1 1 Forkhead domain G_path_suppress PF15991.5 CDS26528.1 - 0.65 10.1 13.9 1.1 9.4 13.9 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor MT PF12777.7 CDS26529.1 - 1.8e-160 533.6 11.1 3.2e-160 532.8 11.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CDS26529.1 - 2.5e-159 529.5 0.1 4e-153 509.2 0.0 3.5 4 0 0 4 4 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS26529.1 - 1.6e-113 379.8 11.2 1.6e-113 379.8 11.2 4.4 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDS26529.1 - 4.8e-100 335.8 3.5 1.6e-62 211.9 2.9 4.2 5 0 0 5 5 4 2 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CDS26529.1 - 1.7e-94 316.0 0.0 1.2e-93 313.2 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDS26529.1 - 2.5e-92 309.4 0.0 8.3e-92 307.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CDS26529.1 - 1.1e-80 269.9 0.7 1.1e-80 269.9 0.7 3.2 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS26529.1 - 3.7e-73 244.9 0.2 1.8e-66 223.1 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS26529.1 - 9.3e-55 184.9 0.1 1.2e-51 174.8 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDS26529.1 - 2.8e-40 136.6 6.2 3.4e-40 136.3 2.0 3.2 2 0 0 2 2 2 1 AAA+ lid domain Dynein_heavy PF03028.15 CDS26529.1 - 4.1e-40 136.6 0.0 7.5e-37 126.1 0.0 4.0 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDS26529.1 - 6.7e-27 94.2 0.1 2.1e-10 40.7 0.0 5.5 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDS26529.1 - 7.3e-24 84.3 0.1 3.8e-23 82.0 0.1 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CDS26529.1 - 1e-09 38.8 0.1 0.019 15.2 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 CDS26529.1 - 4.5e-08 33.6 0.1 0.034 14.6 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS26529.1 - 9.8e-08 32.6 0.0 0.013 15.9 0.0 5.1 4 0 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 CDS26529.1 - 3.2e-06 26.9 0.0 0.0043 16.8 0.0 3.2 4 0 0 4 4 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CDS26529.1 - 3.3e-05 23.9 0.0 0.056 13.5 0.0 4.1 5 0 0 5 5 3 1 AAA domain AAA_18 PF13238.6 CDS26529.1 - 5.1e-05 23.8 4.9 0.81 10.2 0.0 6.5 8 0 0 8 8 4 1 AAA domain AAA_33 PF13671.6 CDS26529.1 - 7.1e-05 23.0 0.1 0.021 15.0 0.0 4.0 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 CDS26529.1 - 0.00016 21.1 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDS26529.1 - 0.00018 21.3 0.5 4.5 7.0 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 CDS26529.1 - 0.00024 20.9 2.7 4.3 7.0 0.0 4.6 4 0 0 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.6 CDS26529.1 - 0.00032 20.8 0.0 0.8 9.8 0.0 3.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDS26529.1 - 0.00056 19.3 0.1 2.2 7.6 0.0 3.4 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 CDS26529.1 - 0.00079 18.4 0.9 0.47 9.3 0.0 2.7 3 0 0 3 3 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CDS26529.1 - 0.0011 19.0 0.1 0.2 11.6 0.0 3.7 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 CDS26529.1 - 0.0016 18.5 0.1 0.51 10.4 0.0 3.5 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDS26529.1 - 0.0016 18.8 0.0 5.6 7.4 0.0 3.8 3 0 0 3 3 3 0 RNA helicase DUF815 PF05673.13 CDS26529.1 - 0.0055 15.9 0.0 0.86 8.7 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDS26529.1 - 0.0059 16.9 0.5 5.1 7.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CDS26529.1 - 0.0078 16.5 0.0 0.63 10.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 CDS26529.1 - 0.009 15.1 0.0 0.18 10.9 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein PIF1 PF05970.14 CDS26529.1 - 0.017 14.3 0.0 0.36 9.9 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase ATP_bind_1 PF03029.17 CDS26529.1 - 0.021 14.6 2.6 0.82 9.4 0.0 4.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 CDS26529.1 - 0.026 14.0 0.2 39 3.6 0.0 4.2 4 0 0 4 4 4 0 PhoH-like protein ABC_tran PF00005.27 CDS26529.1 - 0.028 14.9 0.1 19 5.8 0.0 4.2 3 0 0 3 3 3 0 ABC transporter Pox_A32 PF04665.12 CDS26529.1 - 0.032 13.7 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Guanylate_kin PF00625.21 CDS26529.1 - 0.042 13.5 0.0 0.66 9.6 0.0 2.7 2 0 0 2 2 2 0 Guanylate kinase FtsK_SpoIIIE PF01580.18 CDS26529.1 - 0.047 13.0 0.0 4.2 6.7 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.6 CDS26529.1 - 0.047 13.3 0.3 0.36 10.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 CDS26529.1 - 0.068 13.2 0.5 1.8 8.6 0.0 3.7 3 0 0 3 3 2 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 CDS26529.1 - 0.17 11.6 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CLP1_P PF16575.5 CDS26529.1 - 0.19 11.5 0.2 0.93 9.3 0.0 2.3 3 0 0 3 3 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Spectrin PF00435.21 CDS26529.1 - 4.1 7.9 0.0 4.1 7.9 0.0 6.6 7 1 0 7 7 3 0 Spectrin repeat ATG16 PF08614.11 CDS26529.1 - 4.2 7.5 20.6 12 6.1 8.3 3.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) EMP24_GP25L PF01105.24 CDS26529.1 - 9 6.2 6.9 1.4 8.8 0.3 2.9 3 0 0 3 3 2 0 emp24/gp25L/p24 family/GOLD DUF1077 PF06417.12 CDS26530.1 - 4.2e-43 146.1 2.8 5.6e-43 145.7 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Ecm29 PF13001.7 CDS26531.1 - 1e-68 232.3 0.1 5.5e-52 177.1 0.0 2.7 2 0 0 2 2 2 2 Proteasome stabiliser HEAT_2 PF13646.6 CDS26531.1 - 4.7e-06 26.9 1.7 0.05 14.0 0.1 5.8 5 1 0 5 5 5 1 HEAT repeats HEAT PF02985.22 CDS26531.1 - 2.4e-05 24.2 3.8 8.4 6.9 0.0 6.8 5 0 0 5 5 5 2 HEAT repeat DUF2267 PF10025.9 CDS26531.1 - 0.13 12.6 0.0 3.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) CENP-B_dimeris PF09026.10 CDS26531.1 - 1.2 9.6 9.5 3.4 8.1 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 CDS26531.1 - 2.4 6.1 10.7 7.2 4.6 10.7 1.7 1 0 0 1 1 1 0 DNA polymerase phi AbiJ_NTD4 PF18863.1 CDS26532.1 - 0.16 12.4 0.4 0.69 10.4 0.1 1.9 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 Ribonuc_P_40 PF08584.11 CDS26533.1 - 1.3e-05 24.6 0.0 8.8e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Innexin PF00876.18 CDS26535.1 - 1.8e-75 254.4 4.1 2.1e-75 254.2 4.1 1.0 1 0 0 1 1 1 1 Innexin SieB PF14163.6 CDS26535.1 - 1.3 8.5 4.8 0.18 11.3 0.5 1.7 2 0 0 2 2 2 0 Super-infection exclusion protein B Integrase_H2C2 PF17921.1 CDS26536.1 - 1e-10 41.5 0.3 1.9e-10 40.7 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain VHS PF00790.19 CDS26538.1 - 3.3e-10 40.0 2.4 4.5e-10 39.5 0.2 2.2 2 0 0 2 2 2 1 VHS domain zf-C2H2_3rep PF18868.1 CDS26538.1 - 1.7e-05 25.5 0.3 1.7e-05 25.5 0.3 2.4 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CDS26538.1 - 0.00014 22.1 1.9 0.037 14.3 0.3 3.9 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDS26538.1 - 0.0024 18.6 0.5 3.6 8.7 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS26538.1 - 0.13 12.8 8.4 0.89 10.1 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.12 CDS26538.1 - 0.25 11.5 13.4 3.5 7.8 0.1 4.9 5 0 0 5 5 5 0 DBF zinc finger zinc_ribbon_6 PF14599.6 CDS26538.1 - 0.32 11.0 3.2 7.3 6.7 0.5 3.7 3 1 0 3 3 3 0 Zinc-ribbon zf-RRPl_C4 PF17026.5 CDS26538.1 - 3.5 7.8 8.0 1 9.5 0.1 3.7 4 1 0 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type FANCL_C PF11793.8 CDS26539.1 - 0.015 15.4 1.7 0.04 14.1 1.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 CDS26539.1 - 0.05 13.7 6.6 0.18 11.9 6.6 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 CDS26539.1 - 0.11 12.4 6.9 0.29 11.0 6.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.6 CDS26539.1 - 0.18 12.1 0.0 0.8 10.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain PHD PF00628.29 CDS26539.1 - 0.28 11.1 5.1 0.72 9.8 5.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CDS26539.1 - 0.49 10.8 7.5 1.6 9.1 7.5 1.9 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 CDS26539.1 - 8.5 6.6 7.0 2.2e+02 2.0 7.1 2.6 1 1 1 2 2 2 0 PHD-finger Sulphotransf PF09037.10 CDS26540.1 - 0.0093 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Stf0 sulphotransferase SH3_9 PF14604.6 CDS26541.1 - 9.6e-27 92.6 2.5 2.5e-12 46.4 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDS26541.1 - 6.1e-24 83.4 1.2 6.1e-11 41.7 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDS26541.1 - 6.3e-16 57.8 1.2 1.8e-07 30.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Baculo_PEP_C PF04513.12 CDS26541.1 - 0.006 16.6 0.9 0.01 15.9 0.9 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 CDS26541.1 - 0.023 14.2 5.9 0.039 13.4 5.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tektin PF03148.14 CDS26541.1 - 0.048 12.4 4.6 0.07 11.9 4.6 1.2 1 0 0 1 1 1 0 Tektin family Leptin PF02024.15 CDS26541.1 - 0.11 12.2 0.9 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 Leptin PIN_8 PF18476.1 CDS26541.1 - 0.12 12.3 1.8 0.2 11.5 1.8 1.3 1 0 0 1 1 1 0 PIN like domain DUF4208 PF13907.6 CDS26541.1 - 0.16 12.4 0.6 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) SGT1 PF07093.11 CDS26541.1 - 0.18 10.2 2.3 0.24 9.8 2.3 1.1 1 0 0 1 1 1 0 SGT1 protein LMP PF04778.12 CDS26541.1 - 0.19 11.6 2.7 1.3 9.0 0.9 2.7 2 1 0 2 2 2 0 LMP repeated region Uso1_p115_C PF04871.13 CDS26541.1 - 0.24 11.7 2.4 0.83 10.0 0.1 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 CDS26541.1 - 0.26 10.3 4.2 0.39 9.8 4.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 CDS26541.1 - 0.47 10.5 4.3 4.3 7.4 4.4 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 CDS26541.1 - 0.52 10.6 2.4 1.3 9.3 0.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 CDS26541.1 - 1.1 9.4 8.9 0.57 10.3 5.4 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation FlxA PF14282.6 CDS26541.1 - 1.2 9.1 6.0 4.1 7.5 5.3 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 CDS26541.1 - 1.6 8.8 6.4 1.9 8.5 4.0 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CDS26541.1 - 3.9 8.2 7.7 5 7.8 4.0 2.5 1 1 2 3 3 3 0 SlyX Yip1 PF04893.17 CDS26542.1 - 6.8e-08 32.4 13.6 1.1e-07 31.8 12.6 1.8 1 1 0 1 1 1 1 Yip1 domain O-antigen_lig PF13425.6 CDS26542.1 - 0.00025 20.0 2.4 0.0029 16.4 2.4 1.9 1 1 0 1 1 1 1 O-antigen ligase like membrane protein Tetraspanin PF00335.20 CDS26542.1 - 0.0072 16.1 1.3 0.027 14.2 0.1 2.0 2 0 0 2 2 2 1 Tetraspanin family DUF3487 PF11990.8 CDS26542.1 - 0.06 13.2 0.4 0.06 13.2 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Wzy_C_2 PF11846.8 CDS26542.1 - 0.083 12.8 0.3 0.36 10.7 0.0 2.0 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TMEM132D_C PF15706.5 CDS26542.1 - 0.14 12.0 2.6 1.1 9.1 2.6 2.3 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term tRNA_anti-like PF12869.7 CDS26542.1 - 0.19 11.4 0.1 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 tRNA_anti-like YwiC PF14256.6 CDS26542.1 - 0.84 10.0 6.4 1.5 9.1 3.6 2.1 2 0 0 2 2 2 0 YwiC-like protein EphA2_TM PF14575.6 CDS26542.1 - 1.7 9.6 7.1 39 5.2 0.1 3.6 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3810 PF12725.7 CDS26542.1 - 4.1 6.7 6.7 0.39 10.0 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF2070 PF09843.9 CDS26542.1 - 9.4 4.4 11.1 13 4.0 11.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 53-BP1_Tudor PF09038.10 CDS26543.1 - 3.6e-11 43.1 0.0 7.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT_3 PF18428.1 CDS26543.1 - 0.00069 19.6 0.0 0.0034 17.4 0.0 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.6 CDS26543.1 - 0.026 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 CDS26543.1 - 0.027 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Ank_2 PF12796.7 CDS26544.1 - 1.2e-37 128.4 29.2 2.7e-14 53.5 5.6 4.4 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS26544.1 - 7.3e-33 112.5 15.8 1.4e-07 31.9 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS26544.1 - 7.6e-27 93.0 21.2 1.5e-10 41.1 1.3 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CDS26544.1 - 7e-25 86.3 30.3 3e-05 24.3 0.2 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 CDS26544.1 - 1.5e-23 80.3 20.7 0.0045 17.4 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat DNA_pol3_beta PF00712.19 CDS26544.1 - 0.07 13.3 0.4 1.4 9.1 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain Ank_2 PF12796.7 CDS26546.1 - 5.5e-34 116.6 10.8 1.6e-15 57.5 2.5 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS26546.1 - 2.4e-27 94.6 10.9 8.7e-11 41.8 0.5 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS26546.1 - 3.6e-26 91.2 5.6 6.6e-08 32.9 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CDS26546.1 - 5.6e-25 86.7 9.0 0.0049 17.3 0.8 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CDS26546.1 - 4.9e-22 75.7 10.7 0.0015 18.8 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat HLH PF00010.26 CDS26547.2 - 1.3e-13 50.6 0.4 2e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.10 CDS26547.2 - 0.048 13.6 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cas9-BH PF16593.5 CDS26547.2 - 0.066 12.9 2.8 0.17 11.7 2.8 1.6 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Y_phosphatase PF00102.27 CDS26549.1 - 5.5e-20 71.9 0.0 1.6e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 CDS26549.1 - 5.4e-11 42.7 0.0 1.6e-07 31.6 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain HEPN_STY4199 PF18729.1 CDS26549.1 - 0.22 10.7 0.2 0.33 10.1 0.2 1.2 1 0 0 1 1 1 0 STY4199-like HEPN UCH PF00443.29 CDS26550.1 - 9e-33 113.8 0.1 1.7e-32 113.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDS26550.1 - 6.5e-13 48.8 3.0 1.3e-12 47.8 3.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDS26550.1 - 0.0014 18.3 0.2 0.0096 15.5 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SH3_17 PF18350.1 CDS26550.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain zf-UBP_var PF17807.1 CDS26550.1 - 0.32 10.8 5.1 0.16 11.8 1.7 2.1 2 0 0 2 2 2 0 Variant UBP zinc finger PRP21_like_P PF12230.8 CDS26551.1 - 2.8e-47 161.4 4.3 2.1e-46 158.6 4.3 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CDS26551.1 - 2.4e-43 145.9 5.6 3.8e-23 81.2 0.2 2.7 2 0 0 2 2 2 2 Surp module GCFC PF07842.12 CDS26552.1 - 1.2e-19 71.0 5.4 6.2e-18 65.4 5.4 2.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein BBP1_N PF15271.6 CDS26552.1 - 0.99 10.2 6.9 0.098 13.4 1.2 2.3 3 0 0 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein JmjN PF02375.17 CDS26553.1 - 0.11 12.5 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 jmjN domain Pkinase PF00069.25 CDS26553.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 CDS26554.1 - 3.1e-54 184.1 0.0 3.9e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26554.1 - 2.3e-30 105.7 0.0 5.9e-30 104.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS26554.1 - 0.00075 19.5 0.0 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS26554.1 - 0.002 17.5 0.0 0.0042 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDS26554.1 - 0.0021 17.1 0.0 0.003 16.5 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDS26554.1 - 0.0064 15.6 0.7 0.02 13.9 0.6 1.8 1 1 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CDS26554.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3950 PF13132.6 CDS26554.1 - 0.18 11.6 0.1 0.5 10.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Pkinase PF00069.25 CDS26555.1 - 1.2e-55 188.7 0.0 1.5e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26555.1 - 1.2e-26 93.6 0.0 1.8e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26555.1 - 4.5e-06 26.2 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS26555.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDS26555.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CDS26555.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDS26555.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS26555.1 - 0.091 11.7 0.0 0.25 10.2 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CDS26555.1 - 0.24 10.1 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CDS26556.1 - 1.1e-58 198.7 0.0 1.4e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26556.1 - 6.6e-26 91.1 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS26556.1 - 0.0003 19.8 1.0 0.00043 19.3 1.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS26556.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS26556.1 - 0.057 12.8 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OTU PF02338.19 CDS26557.1 - 4.1e-19 69.3 0.0 9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 CDS26557.1 - 0.0085 15.4 2.0 0.018 14.4 2.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Pkinase PF00069.25 CDS26558.1 - 1.2e-97 326.4 0.0 2.1e-56 191.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26558.1 - 5.3e-51 173.4 0.0 1.7e-29 102.9 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS26558.1 - 4.7e-12 45.5 0.0 2.8e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 CDS26558.1 - 5.8e-08 33.0 0.1 0.31 10.9 0.1 3.4 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 CDS26558.1 - 1.8e-06 27.4 0.2 0.023 14.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDS26558.1 - 0.0019 17.8 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDS26558.1 - 0.0032 16.8 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like bZIP_1 PF00170.21 CDS26559.1 - 4.2e-11 42.8 8.4 4.2e-11 42.8 8.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CDS26559.1 - 7.6e-08 32.3 6.5 7.6e-08 32.3 6.5 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS26559.1 - 2.6e-06 27.9 6.6 8.3e-06 26.2 6.6 1.9 1 0 0 1 1 1 1 bZIP Maf transcription factor Jun PF03957.13 CDS26559.1 - 0.00021 21.3 5.3 0.00064 19.7 5.3 1.9 1 1 0 1 1 1 1 Jun-like transcription factor CENP-F_leu_zip PF10473.9 CDS26559.1 - 0.023 14.7 5.1 0.041 13.9 3.8 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 CDS26559.1 - 0.034 14.8 2.3 0.034 14.8 2.3 2.2 2 0 0 2 2 2 0 SlyX DivIVA PF05103.13 CDS26559.1 - 0.041 14.0 1.1 0.099 12.7 1.1 1.6 1 0 0 1 1 1 0 DivIVA protein FlaC_arch PF05377.11 CDS26559.1 - 0.067 13.6 3.7 0.14 12.6 0.3 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RhoGAP PF00620.27 CDS26560.2 - 9.1e-57 191.1 5.4 3.7e-32 111.3 0.5 2.4 2 0 0 2 2 2 2 RhoGAP domain CRAL_TRIO_2 PF13716.6 CDS26560.2 - 1.6e-19 70.4 0.8 5e-16 59.1 0.1 2.6 1 1 1 2 2 2 2 Divergent CRAL/TRIO domain PGA_cap PF09587.10 CDS26560.2 - 0.11 11.9 0.0 1.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Bacterial capsule synthesis protein PGA_cap Nod1 PF17114.5 CDS26560.2 - 0.12 12.5 1.6 0.95 9.6 0.2 2.5 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 DOT1 PF08123.13 CDS26561.1 - 1.7e-64 217.1 0.1 4.6e-64 215.7 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 TolA_bind_tri PF16331.5 CDS26561.1 - 0.034 14.2 0.6 0.034 14.2 0.6 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Cortex-I_coil PF09304.10 CDS26561.1 - 1.3 9.3 4.4 1 9.6 1.0 2.2 1 1 0 2 2 2 0 Cortexillin I, coiled coil AAA PF00004.29 CDS26563.1 - 1.9e-40 138.4 0.0 5.5e-40 136.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 CDS26563.1 - 3e-17 62.5 0.2 3e-17 62.5 0.2 1.8 2 0 0 2 2 1 1 Bromodomain AAA_lid_3 PF17862.1 CDS26563.1 - 1e-08 34.8 0.0 4.4e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDS26563.1 - 9.9e-06 26.0 3.7 0.00015 22.2 0.1 3.9 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDS26563.1 - 0.00089 19.5 0.0 0.0041 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS26563.1 - 0.002 18.3 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDS26563.1 - 0.0021 18.2 0.0 0.0079 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDS26563.1 - 0.0043 17.1 0.1 0.053 13.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CDS26563.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDS26563.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDS26563.1 - 0.013 15.2 0.2 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDS26563.1 - 0.014 15.3 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CDS26563.1 - 0.027 14.9 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 CDS26563.1 - 0.048 12.7 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 CDS26563.1 - 0.052 14.1 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDS26563.1 - 0.075 12.8 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CDS26563.1 - 0.077 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDS26563.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 CDS26563.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 CDS26563.1 - 0.24 10.6 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FAM76 PF16046.5 CDS26564.1 - 1.6e-91 306.8 24.7 1.6e-91 306.8 24.7 2.0 2 0 0 2 2 2 1 FAM76 protein Herpes_UL6 PF01763.16 CDS26564.1 - 0.038 12.5 1.1 0.057 11.9 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-FPG_IleRS PF06827.14 CDS26564.1 - 0.15 12.0 9.6 3.1 7.7 0.2 4.1 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS BST2 PF16716.5 CDS26564.1 - 0.22 12.1 5.6 0.22 12.1 3.5 2.1 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 JAMP PF05571.12 CDS26564.1 - 5.7 6.5 6.1 10 5.7 6.1 1.4 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein GCV_T PF01571.21 CDS26565.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Menin PF05053.13 CDS26566.1 - 5.6 5.2 4.6 10 4.3 4.6 1.3 1 0 0 1 1 1 0 Menin zf-C2H2 PF00096.26 CDS26567.1 - 1.9e-11 43.7 20.2 0.0011 19.3 1.9 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26567.1 - 1.4e-07 31.6 20.3 2.1e-06 27.9 0.8 5.0 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26567.1 - 3e-07 30.7 25.3 0.011 16.5 2.4 4.9 5 0 0 5 5 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDS26567.1 - 0.014 15.7 15.3 0.3 11.4 9.3 3.6 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CDS26567.1 - 0.016 15.9 0.1 0.016 15.9 0.1 5.5 5 1 1 6 6 5 0 Zinc finger C2H2-type, 3 repeats zf-ribbon_3 PF13248.6 CDS26567.1 - 0.23 10.9 6.3 0.22 11.0 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 CDS26567.1 - 1.4 8.8 8.9 1.1 9.1 0.7 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CDS26567.1 - 1.9 8.6 12.8 0.42 10.7 1.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 CDS26567.1 - 2.5 8.3 14.4 2.6 8.2 3.5 3.0 1 1 1 2 2 2 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 CDS26567.1 - 4.2 7.4 12.0 1.4 8.9 1.3 3.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain LMBR1 PF04791.16 CDS26567.1 - 4.7 6.0 6.9 10 4.9 6.9 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-BED PF02892.15 CDS26567.1 - 5.9 7.0 9.3 3.6 7.7 3.3 2.9 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_8 PF15909.5 CDS26567.1 - 6.2 7.2 12.5 0.32 11.3 3.7 3.4 3 1 1 4 4 3 0 C2H2-type zinc ribbon TF_Zn_Ribbon PF08271.12 CDS26567.1 - 7.2 6.2 7.0 3.9 7.1 0.2 2.7 2 1 1 3 3 3 0 TFIIB zinc-binding ADK_lid PF05191.14 CDS26567.1 - 8.5 6.5 5.5 22 5.1 2.0 2.9 2 1 1 3 3 3 0 Adenylate kinase, active site lid Ets PF00178.22 CDS26570.1 - 1.4e-34 118.4 0.3 2.4e-34 117.6 0.3 1.4 1 0 0 1 1 1 1 Ets-domain DUF1315 PF07023.12 CDS26570.1 - 0.046 13.8 0.7 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1315) PRIMA1 PF16101.5 CDS26570.1 - 0.36 10.9 3.8 0.95 9.5 3.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_carr PF00153.27 CDS26575.1 - 1.2e-38 130.9 2.9 1.5e-13 50.4 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1g PF09334.11 CDS26576.1 - 4.4e-78 262.8 0.0 3e-65 220.5 0.0 4.0 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDS26576.1 - 1.6e-08 33.3 0.3 4.5e-07 28.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CDS26576.1 - 6.7e-06 25.7 0.0 0.0069 15.8 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Pkinase_Tyr PF07714.17 CDS26577.1 - 2.5e-86 289.1 0.0 3.5e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS26577.1 - 6.5e-45 153.5 0.0 9.6e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDS26577.1 - 0.00059 19.3 0.2 0.001 18.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH2 PF00017.24 CDS26577.1 - 0.062 13.4 0.2 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 SH2 domain DUF1604 PF07713.13 CDS26578.1 - 0.027 14.3 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) 7tm_1 PF00001.21 CDS26581.1 - 2.9e-38 131.7 11.6 2.2e-37 128.8 10.1 2.4 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Y_phosphatase PF00102.27 CDS26582.1 - 1.8e-54 184.8 1.2 2.3e-48 164.8 0.1 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDS26582.1 - 0.0002 21.7 4.8 0.48 10.8 0.2 5.9 5 1 0 5 5 5 1 Fibronectin type III domain DSPc PF00782.20 CDS26582.1 - 0.00035 20.4 0.0 0.0088 15.9 0.0 2.8 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS26582.1 - 0.008 16.2 0.2 0.056 13.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDS26582.1 - 0.023 14.8 0.2 0.48 10.5 0.1 2.7 2 1 0 2 2 2 0 Inositol hexakisphosphate EF-hand_7 PF13499.6 CDS26583.1 - 7.9e-23 80.7 3.7 8.3e-16 58.2 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS26583.1 - 8.6e-22 75.0 11.3 3.4e-07 29.3 0.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDS26583.1 - 2.4e-20 70.7 2.5 7.3e-06 25.5 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDS26583.1 - 3.8e-17 61.9 4.0 1.1e-06 28.4 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS26583.1 - 3e-16 58.1 4.6 6.4e-05 22.3 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CDS26583.1 - 2.1e-05 24.4 1.6 0.24 11.4 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS26583.1 - 8e-05 22.9 2.0 0.0095 16.2 0.2 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region MecA_N PF05223.11 CDS26583.1 - 0.00016 21.9 0.5 0.0032 17.7 0.1 2.4 1 1 1 2 2 2 1 NTF2-like N-terminal transpeptidase domain EF-hand_10 PF14788.6 CDS26583.1 - 0.017 15.0 0.9 5.7 6.9 0.1 3.2 2 1 1 3 3 3 0 EF hand Caleosin PF05042.13 CDS26583.1 - 0.052 13.5 2.6 11 5.9 0.0 3.3 1 1 2 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.18 CDS26583.1 - 0.079 13.2 0.0 0.6 10.4 0.0 2.2 2 1 0 2 2 2 0 Dockerin type I domain DUF4921 PF16268.5 CDS26583.1 - 0.096 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) YxiJ PF14176.6 CDS26583.1 - 0.11 13.0 1.8 2 8.9 0.3 2.4 1 1 1 2 2 2 0 YxiJ-like protein EF-hand_9 PF14658.6 CDS26583.1 - 0.12 12.8 0.0 0.41 11.0 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain Exo_endo_phos_2 PF14529.6 CDS26585.1 - 3.6e-13 49.4 0.1 7.5e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26585.1 - 0.00053 19.6 0.0 0.0059 16.1 0.0 2.0 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF5456 PF17539.2 CDS26585.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5456) zf-H2C2_5 PF13909.6 CDS26586.1 - 1.9e-13 49.9 30.3 6e-09 35.5 2.4 5.6 5 1 0 5 5 5 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CDS26586.1 - 6.4e-06 26.4 2.6 6.4e-06 26.4 2.6 6.8 7 0 0 7 7 7 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS26586.1 - 8.7e-06 26.2 34.2 0.018 15.8 1.5 6.6 6 0 0 6 6 6 3 C2H2-type zinc finger AKAP95 PF04988.12 CDS26586.1 - 4e-05 23.9 9.8 1.1 9.5 1.8 4.4 4 0 0 4 4 4 2 A-kinase anchoring protein 95 (AKAP95) Actin_micro PF17003.5 CDS26586.1 - 0.0001 21.6 3.3 0.37 9.9 2.9 3.5 2 2 1 3 3 3 1 Putative actin-like family zf-C2H2_3rep PF18868.1 CDS26586.1 - 0.0057 17.3 8.1 5 7.8 0.1 4.8 4 1 1 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 CDS26586.1 - 0.036 14.5 32.2 0.089 13.3 0.7 6.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type CbiG_N PF11760.8 CDS26586.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal CpXC PF14353.6 CDS26586.1 - 0.24 11.5 5.5 9.5 6.3 0.0 4.3 4 1 1 5 5 5 0 CpXC protein zf-C2H2_2 PF12756.7 CDS26586.1 - 0.24 11.8 19.9 0.066 13.5 1.1 5.0 4 1 2 6 6 6 0 C2H2 type zinc-finger (2 copies) TFIIS_C PF01096.18 CDS26586.1 - 0.74 9.7 4.6 27 4.7 0.1 3.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.6 CDS26586.1 - 4.8 7.2 6.9 27 4.8 0.4 3.6 3 0 0 3 3 3 0 Nudix N-terminal DNA_RNApol_7kD PF03604.13 CDS26586.1 - 6.1 6.6 5.8 36 4.2 0.1 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L32p PF01783.23 CDS26586.1 - 6.3 7.1 7.2 16 5.8 1.5 3.1 2 0 0 2 2 2 0 Ribosomal L32p protein family PP2C PF00481.21 CDS26589.1 - 1e-20 74.5 0.0 3.2e-15 56.5 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C DUF4993 PF16384.5 CDS26589.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Cwf_Cwc_15 PF04889.12 CDS26590.1 - 1 9.1 24.0 0.57 9.9 2.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NIF PF03031.18 CDS26594.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CDS26594.1 - 0.025 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) REC114-like PF15165.6 CDS26595.1 - 2e-17 63.8 0.0 4.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Meiotic recombination protein REC114-like DUF667 PF05018.13 CDS26596.1 - 5.3e-92 306.6 1.2 6e-92 306.5 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) EF-hand_7 PF13499.6 CDS26598.1 - 1.5e-18 67.0 1.3 0.001 19.4 0.1 4.7 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 CDS26598.1 - 2e-17 61.4 5.3 1.5e-05 24.2 0.1 6.0 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CDS26598.1 - 3.8e-15 54.5 4.6 0.0063 16.4 0.0 5.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 CDS26598.1 - 1.6e-14 53.5 0.7 8.7e-05 22.3 0.0 5.0 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS26598.1 - 3.1e-07 29.6 4.4 0.00015 21.1 0.1 4.4 5 0 0 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.9 CDS26598.1 - 0.023 15.0 0.0 5.5 7.3 0.0 3.3 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS26598.1 - 0.042 14.2 0.1 72 3.8 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain zf-H2C2_2 PF13465.6 CDS26599.1 - 4.6e-32 109.0 31.9 7.1e-08 32.5 1.0 7.1 8 0 0 8 8 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS26599.1 - 2.7e-30 103.1 40.1 1.5e-05 25.2 0.3 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS26599.1 - 1.4e-25 87.7 40.7 9.2e-05 23.0 0.4 6.8 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS26599.1 - 4.7e-18 64.7 24.2 4.5e-05 23.3 0.0 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS26599.1 - 5.8e-18 64.7 14.5 0.0031 17.8 0.0 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS26599.1 - 2.5e-11 43.6 27.5 0.052 14.0 0.3 6.0 6 0 0 6 6 5 5 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CDS26599.1 - 4.7e-09 35.8 28.3 0.0065 16.2 0.3 6.9 6 0 0 6 6 6 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDS26599.1 - 3.9e-07 30.2 21.3 0.00052 20.2 4.0 4.4 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDS26599.1 - 0.00014 22.2 22.1 0.31 11.4 4.2 5.3 1 1 3 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CDS26599.1 - 0.00015 22.0 15.2 0.0019 18.4 1.5 3.9 1 1 1 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CDS26599.1 - 0.00029 20.5 27.8 0.12 12.2 0.1 5.9 6 1 0 6 6 5 3 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 CDS26599.1 - 0.0013 19.1 5.6 0.47 11.0 0.2 3.7 4 0 0 4 4 3 2 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 CDS26599.1 - 0.0041 17.5 17.7 1.5 9.3 0.0 5.3 2 1 2 4 4 4 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 CDS26599.1 - 0.013 15.4 2.1 0.16 11.9 0.2 5.2 6 0 0 6 6 6 0 zinc-finger of a C2HC-type GAGA PF09237.11 CDS26599.1 - 0.032 14.0 0.2 0.032 14.0 0.2 4.3 4 1 1 5 5 4 0 GAGA factor Rad50_zn_hook PF04423.14 CDS26599.1 - 0.098 12.5 8.5 2.4 8.1 0.1 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif PHF5 PF03660.14 CDS26599.1 - 0.19 11.9 9.3 1 9.6 0.1 3.1 2 1 1 3 3 3 0 PHF5-like protein PyrI_C PF02748.15 CDS26599.1 - 0.71 9.8 5.9 3.5 7.6 0.0 3.8 3 2 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.12 CDS26599.1 - 0.78 10.0 18.3 0.88 9.9 2.0 4.2 1 1 1 3 3 3 0 TFIIH C1-like domain Elf1 PF05129.13 CDS26599.1 - 0.88 9.7 15.8 1.6 8.9 2.9 3.7 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like zf_ZIC PF18366.1 CDS26599.1 - 0.89 9.7 14.1 13 6.0 0.7 4.9 3 1 2 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_9 PF16293.5 CDS26599.1 - 1.2 9.1 12.4 0.82 9.6 0.1 4.6 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 CDS26599.1 - 1.5 8.9 28.3 31 4.7 6.8 6.2 2 1 2 4 4 4 0 BED zinc finger zf-CHCC PF10276.9 CDS26599.1 - 1.8 8.7 13.7 11 6.2 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger domain DUF2225 PF09986.9 CDS26599.1 - 2.2 8.0 13.9 2.1 8.0 0.2 4.5 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) FYVE PF01363.21 CDS26599.1 - 3.9 7.7 25.1 57 3.9 9.1 4.8 1 1 2 3 3 3 0 FYVE zinc finger DUF3268 PF11672.8 CDS26599.1 - 4 7.8 9.5 2.6 8.4 2.2 2.8 1 1 0 2 2 2 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 CDS26599.1 - 5.1 7.3 14.3 23 5.2 0.1 4.3 3 2 1 4 4 4 0 Zinc ribbon domain Ribosomal_L44 PF00935.19 CDS26600.1 - 2.2e-36 124.1 14.7 3.9e-36 123.4 14.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 LRV_FeS PF05484.11 CDS26600.1 - 1.7 8.7 6.3 0.53 10.3 0.7 2.1 2 0 0 2 2 2 0 LRV protein FeS4 cluster Ribosomal_L37e PF01907.19 CDS26601.1 - 8.1e-29 99.5 13.4 1.3e-28 98.9 13.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 CDS26601.1 - 0.0073 16.4 0.8 0.0082 16.2 0.8 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 CDS26601.1 - 0.011 15.8 2.4 0.018 15.1 2.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CDS26601.1 - 0.081 12.4 3.3 0.15 11.5 3.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 CDS26601.1 - 0.17 11.9 3.4 0.21 11.6 3.2 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 CDS26601.1 - 0.2 11.2 7.0 0.55 9.7 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) FeS PF04060.13 CDS26601.1 - 0.35 10.6 4.1 9 6.1 0.2 2.4 2 0 0 2 2 2 0 Putative Fe-S cluster zn-ribbon_14 PF16503.5 CDS26601.1 - 0.87 9.1 6.2 2.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon zinc_ribbon_2 PF13240.6 CDS26601.1 - 1.3 8.8 5.8 8 6.3 5.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 CDS26601.1 - 1.9 8.5 7.4 1.9 8.5 0.7 2.3 1 1 1 2 2 2 0 YhfH-like protein PCNA_N PF00705.18 CDS26602.1 - 1.5e-53 179.8 0.9 2.6e-53 179.1 0.9 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CDS26602.1 - 2.7e-52 176.3 0.1 1.6e-51 173.8 0.0 2.0 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CDS26602.1 - 1.8e-07 30.5 0.1 6.3e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CDS26602.1 - 0.00018 21.1 0.0 0.00023 20.7 0.0 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CDS26602.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Hus1-like protein WYL PF13280.6 CDS26602.1 - 0.2 11.7 0.0 0.58 10.2 0.0 1.7 2 1 0 2 2 2 0 WYL domain Pkinase PF00069.25 CDS26603.1 - 1.5e-28 99.9 0.0 4.8e-28 98.3 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26603.1 - 3.1e-12 46.3 0.1 4.1e-11 42.6 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase JIP_LZII PF16471.5 CDS26603.1 - 0.016 15.3 1.3 0.038 14.2 1.3 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II RasGEF_N PF00618.20 CDS26603.1 - 0.026 14.7 0.1 0.078 13.2 0.1 1.7 1 0 0 1 1 1 0 RasGEF N-terminal motif Cep57_CLD_2 PF14197.6 CDS26603.1 - 0.03 14.4 0.6 0.076 13.1 0.6 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Pox_ser-thr_kin PF05445.11 CDS26603.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pox_A_type_inc PF04508.12 CDS26603.1 - 0.32 10.9 10.8 2.5 8.1 3.0 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Bud13 PF09736.9 CDS26604.1 - 2.1e-33 115.8 27.8 2.8e-32 112.1 27.8 2.3 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Auxin_canalis PF05703.11 CDS26604.1 - 0.17 11.8 5.7 0.21 11.5 5.7 1.2 1 0 0 1 1 1 0 Auxin canalisation Mit_KHE1 PF10173.9 CDS26604.1 - 3.8 7.6 7.2 5.7 7.0 7.2 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related FancD2 PF14631.6 CDS26604.1 - 5.6 4.2 7.4 7.6 3.8 7.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2347 PF09804.9 CDS26604.1 - 6 6.4 8.2 5.7 6.4 7.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TFIIA PF03153.13 CDS26606.2 - 1.4 8.9 18.3 1.8 8.5 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Scs3p PF10261.9 CDS26607.2 - 1.8e-29 103.0 7.0 3.6e-29 102.0 7.0 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM CBFD_NFYB_HMF PF00808.23 CDS26608.2 - 2.8e-13 49.9 0.1 6.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 CDS26608.2 - 6.4e-05 23.1 0.4 0.00025 21.2 0.2 1.9 2 0 0 2 2 2 1 CENP-W protein Histone PF00125.24 CDS26608.2 - 0.0017 18.7 0.1 0.0041 17.5 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS26608.2 - 0.0036 17.4 0.7 0.01 16.0 0.7 1.8 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CDS26608.2 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Ribosom_S12_S23 PF00164.25 CDS26610.2 - 3.3e-25 87.9 0.2 6.1e-25 87.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyltransferase PF01553.21 CDS26610.2 - 1.8e-18 66.5 0.0 3.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CDS26610.2 - 4.4e-08 33.1 0.1 2.5e-05 24.3 0.1 2.4 1 1 1 2 2 2 2 Acyltransferase C-terminus V-SNARE_C PF12352.8 CDS26611.2 - 8.1e-05 22.8 0.5 8.1e-05 22.8 0.5 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Nmad5 PF18757.1 CDS26611.2 - 0.0016 18.7 0.3 0.0024 18.1 0.3 1.2 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 Occludin_ELL PF07303.13 CDS26611.2 - 0.053 14.2 0.5 0.11 13.3 0.1 1.7 2 0 0 2 2 2 0 Occludin homology domain HeLo PF14479.6 CDS26611.2 - 0.071 12.9 1.4 0.38 10.6 0.1 2.2 1 1 1 2 2 2 0 Prion-inhibition and propagation Defb50 PF17546.2 CDS26611.2 - 1.5 8.8 4.4 4.9 7.1 1.4 2.5 2 1 0 2 2 2 0 Beta defensin 50 CENP-S PF15630.6 CDS26612.1 - 1.2e-18 67.2 0.1 2.3e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDS26612.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CDS26612.1 - 0.0082 16.1 0.1 0.024 14.6 0.1 1.8 1 1 1 2 2 2 1 Bromodomain associated Ank_2 PF12796.7 CDS26613.1 - 2.6e-08 34.3 0.0 4.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS26613.1 - 2.2e-05 24.6 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS26613.1 - 4.1e-05 24.1 0.0 0.00028 21.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDS26613.1 - 0.00022 21.5 0.0 0.0023 18.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CDS26613.1 - 0.00035 20.8 0.0 0.0017 18.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Kinesin PF00225.23 CDS26614.2 - 1.1e-58 198.7 0.7 9e-58 195.8 0.6 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDS26614.2 - 1.7e-34 118.9 0.1 3.8e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding SYCE1 PF15233.6 CDS26614.2 - 0.011 15.8 4.3 0.011 15.8 4.3 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF3450 PF11932.8 CDS26614.2 - 0.029 13.7 1.2 0.052 12.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4309 PF14172.6 CDS26614.2 - 0.11 12.5 0.5 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) Hom_end_hint PF05203.16 CDS26614.2 - 0.16 11.9 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint PI3K_P85_iSH2 PF16454.5 CDS26614.2 - 0.25 10.9 7.7 0.63 9.6 7.7 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rrn6 PF10214.9 CDS26614.2 - 0.5 8.8 4.5 0.089 11.3 0.9 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor hSac2 PF12456.8 CDS26615.2 - 4.2e-19 68.3 0.0 6.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Inositol phosphatase Tcf25 PF04910.14 CDS26616.1 - 1e-94 317.5 5.0 1.4e-94 317.1 5.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 pP_pnuc_1 PF18165.1 CDS26616.1 - 0.11 12.4 0.8 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Lig_chan PF00060.26 CDS26617.1 - 9e-54 181.4 0.6 1.4e-53 180.7 0.6 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDS26617.1 - 1.4e-37 128.4 0.0 2.7e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDS26617.1 - 7.4e-20 71.3 0.0 2.7e-19 69.5 0.0 2.0 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDS26617.1 - 3.7e-11 42.7 0.0 7.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region KcnmB2_inactiv PF09303.10 CDS26617.1 - 0.098 12.5 0.4 0.34 10.8 0.4 1.9 1 0 0 1 1 1 0 KCNMB2, ball and chain domain ANF_receptor PF01094.28 CDS26618.2 - 9.3e-10 38.1 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CDS26618.2 - 0.00047 19.9 0.0 0.00067 19.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Lig_chan PF00060.26 CDS26619.1 - 2.2e-48 163.9 0.1 3.6e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDS26619.1 - 1.8e-34 118.4 0.0 3.2e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.28 CDS26619.1 - 7.3e-24 84.5 0.1 1.3e-23 83.7 0.1 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.20 CDS26619.1 - 1.4e-18 67.2 0.0 7.1e-18 64.9 0.0 2.1 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.6 CDS26619.1 - 0.00016 21.5 0.1 0.00034 20.4 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Ion_trans_2 PF07885.16 CDS26619.1 - 0.016 15.2 2.2 0.038 13.9 2.2 1.7 1 0 0 1 1 1 0 Ion channel KcnmB2_inactiv PF09303.10 CDS26619.1 - 0.11 12.3 0.2 0.34 10.8 0.2 1.8 1 0 0 1 1 1 0 KCNMB2, ball and chain domain 7tm_2 PF00002.24 CDS26621.1 - 2.7e-08 33.4 18.0 4.6e-08 32.6 18.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) YqhR PF11085.8 CDS26622.1 - 0.11 12.4 0.1 8.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved membrane protein YqhR Pkinase PF00069.25 CDS26623.1 - 1.4e-66 224.6 0.0 2.7e-66 223.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26623.1 - 9e-34 116.9 0.0 1.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26623.1 - 1.3e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 CDS26623.1 - 0.0001 22.0 0.2 0.00028 20.6 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 APH PF01636.23 CDS26623.1 - 0.00035 20.6 0.0 0.00095 19.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS26623.1 - 0.00092 18.6 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDS26623.1 - 0.0055 16.3 0.1 0.078 12.6 0.0 2.3 1 1 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CDS26623.1 - 0.057 12.4 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CDS26623.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EF-hand_1 PF00036.32 CDS26624.1 - 1.3e-23 80.7 4.3 1.7e-05 24.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS26624.1 - 1.1e-22 80.2 1.3 4e-10 40.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS26624.1 - 1.4e-21 74.5 2.4 0.00036 20.2 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS26624.1 - 3.6e-20 70.5 3.4 0.00013 21.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS26624.1 - 2e-17 62.8 5.2 5.6e-05 22.9 0.1 4.2 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS26624.1 - 3.1e-08 33.9 0.0 0.0052 17.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS26624.1 - 7.8e-06 26.1 0.1 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CDS26624.1 - 8.2e-05 22.5 0.1 0.059 13.3 0.0 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDS26624.1 - 0.00098 19.1 0.1 1.4 8.9 0.0 3.4 3 1 1 4 4 4 1 Caleosin related protein EF-hand_10 PF14788.6 CDS26624.1 - 0.0084 15.9 0.4 6.7 6.7 0.0 3.2 2 1 1 3 3 3 1 EF hand DUF2313 PF10076.9 CDS26624.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DUF1744 PF08490.12 CDS26625.1 - 2e-94 316.5 0.0 6.3e-94 314.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CDS26625.1 - 1.9e-69 234.4 0.0 3.7e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDS26625.1 - 5.6e-11 41.8 0.0 3e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CDS26625.1 - 6.6e-10 39.0 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CDS26625.1 - 2.3e-05 24.5 0.0 7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily zinc_ribbon_4 PF13717.6 CDS26625.1 - 5.7 6.9 7.8 4.1 7.4 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zip PF02535.22 CDS26626.1 - 1.5e-20 73.7 3.5 2e-19 70.0 3.5 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter CD20 PF04103.15 CDS26626.1 - 0.011 15.8 1.3 1.6 8.8 0.4 2.5 2 0 0 2 2 2 0 CD20-like family BAGE PF08180.11 CDS26626.1 - 0.22 11.6 1.4 0.56 10.3 1.4 1.7 1 0 0 1 1 1 0 B melanoma antigen family QCR10 PF09796.9 CDS26626.1 - 4 7.6 6.1 2.8 8.1 0.0 2.9 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LRR_8 PF13855.6 CDS26628.1 - 7.1e-44 147.4 28.0 5.5e-11 42.1 1.8 6.9 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CDS26628.1 - 9.5e-22 76.7 27.6 9.3e-06 25.9 0.5 7.2 4 1 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDS26628.1 - 2.1e-17 63.3 0.0 2.5e-06 27.5 0.0 3.3 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDS26628.1 - 2.5e-11 42.5 28.6 0.33 11.7 0.9 9.9 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.6 CDS26628.1 - 1.2e-08 34.7 2.4 4.7e-05 23.0 0.0 3.8 2 2 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 CDS26628.1 - 0.0012 18.7 28.8 3.4 8.0 0.2 7.6 8 0 0 8 8 8 4 Leucine Rich repeat PRIMA1 PF16101.5 CDS26628.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3262 PF11660.8 CDS26628.1 - 0.089 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Forkhead PF00250.18 CDS26629.1 - 4.9e-35 119.6 0.6 4.9e-35 119.6 0.6 2.7 3 1 0 3 3 3 1 Forkhead domain DUF229 PF02995.17 CDS26630.1 - 5.2e-89 299.1 0.0 7.1e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 CDS26630.1 - 2.6e-07 30.4 0.0 0.017 14.5 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 CDS26630.1 - 0.15 11.6 0.0 0.81 9.2 0.0 1.9 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Innexin PF00876.18 CDS26631.1 - 2.7e-90 303.2 7.5 3.3e-90 302.9 7.5 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 CDS26633.1 - 1.3e-71 241.8 13.2 1.4e-71 241.6 13.2 1.0 1 0 0 1 1 1 1 Innexin HEAT PF02985.22 CDS26635.1 - 9.1e-17 59.7 14.6 0.13 12.6 0.1 10.5 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 CDS26635.1 - 2.1e-08 34.4 0.6 0.082 13.3 0.0 6.6 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 CDS26635.1 - 8.3e-07 29.4 9.4 20 5.8 0.0 8.1 8 0 0 8 8 8 1 HEAT-like repeat Tti2 PF10521.9 CDS26635.1 - 6.1e-06 26.0 1.5 0.011 15.4 0.0 4.1 3 1 1 4 4 4 1 Tti2 family Cnd1 PF12717.7 CDS26635.1 - 1.9e-05 24.8 3.3 0.048 13.7 0.0 4.8 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 CDS26635.1 - 5e-05 23.1 0.4 0.78 9.5 0.4 4.5 4 1 1 5 5 5 2 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 CDS26635.1 - 0.0073 16.6 1.6 0.057 13.7 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 CDS26635.1 - 0.43 10.5 5.8 1.8 8.5 5.8 2.1 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal U3snoRNP10 PF12397.8 CDS26635.1 - 1.2 9.5 5.3 2.3 8.6 0.2 3.7 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 PHD PF00628.29 CDS26636.1 - 5.6e-28 96.6 35.4 9.4e-10 38.2 5.7 3.5 3 0 0 3 3 3 3 PHD-finger DDT PF02791.17 CDS26636.1 - 2.2e-14 53.5 0.1 8.9e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 CDS26636.1 - 0.0011 19.3 2.6 0.0013 19.2 0.0 2.6 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bromodomain PF00439.25 CDS26636.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain WHIM1 PF15612.6 CDS26636.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 zf-HC5HC2H PF13771.6 CDS26636.1 - 0.15 12.3 17.2 1.1 9.6 1.1 3.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain PHD_4 PF16866.5 CDS26636.1 - 1.2 9.2 35.0 0.022 14.8 4.2 3.8 3 0 0 3 3 3 0 PHD-finger Dor1 PF04124.12 CDS26636.1 - 3.8 6.1 8.6 12 4.5 0.1 2.5 2 0 0 2 2 2 0 Dor1-like family Rubredoxin PF00301.20 CDS26636.1 - 4.9 7.3 16.8 0.33 11.0 1.2 4.0 3 1 0 3 3 3 0 Rubredoxin dCache_1 PF02743.18 CDS26638.1 - 4.5e-13 49.6 0.2 5.5e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 Cache domain VWA_N PF08399.11 CDS26638.1 - 0.00069 20.1 0.1 0.0021 18.5 0.1 1.9 1 0 0 1 1 1 1 VWA N-terminal Proteasome PF00227.26 CDS26639.1 - 2.7e-59 199.8 0.0 3.6e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDS26639.1 - 2.5e-11 43.0 0.0 5.9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature 7TM_GPCR_Srx PF10328.9 CDS26640.1 - 6.4e-05 22.7 20.0 0.00018 21.2 19.7 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CDS26640.1 - 0.0092 15.3 14.4 0.014 14.8 14.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0220 PF05255.11 CDS26640.1 - 0.073 12.6 0.0 0.073 12.6 0.0 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) Serpentine_r_xa PF03383.15 CDS26640.1 - 0.3 11.1 10.1 0.039 13.9 3.0 2.7 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Gtr1_RagA PF04670.12 CDS26642.1 - 1.5e-62 211.0 1.6 2.2e-62 210.4 1.6 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CDS26642.1 - 2.8e-05 23.6 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS26642.1 - 7.5e-05 22.9 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDS26642.1 - 0.00013 22.1 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS26642.1 - 0.00036 20.1 0.1 0.00053 19.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDS26642.1 - 0.00047 19.6 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF815 PF05673.13 CDS26642.1 - 0.049 12.8 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDS26642.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 CDS26642.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1765 PF08578.10 CDS26642.1 - 0.13 12.7 0.4 0.36 11.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Chlorophyllase2 PF12740.7 CDS26643.1 - 0.0039 16.1 0.0 0.0044 16.0 0.0 1.0 1 0 0 1 1 1 1 Chlorophyllase enzyme B12D PF06522.11 CDS26643.1 - 0.11 12.3 0.6 0.3 10.9 0.4 1.8 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit eIF-3_zeta PF05091.12 CDS26644.1 - 2.5e-179 597.6 0.1 3e-179 597.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CDS26644.1 - 0.059 12.9 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Pkinase_Tyr PF07714.17 CDS26646.2 - 2.7e-172 570.9 0.0 3e-86 288.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS26646.2 - 5.3e-82 275.1 0.0 1.8e-41 142.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain SH2 PF00017.24 CDS26646.2 - 9.7e-21 73.7 0.1 1.9e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDS26646.2 - 2e-12 46.5 0.0 4.3e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS26646.2 - 6.2e-12 45.2 0.1 1.8e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CDS26646.2 - 5.5e-09 35.6 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Haspin_kinase PF12330.8 CDS26646.2 - 3.6e-08 32.7 0.1 0.0081 15.1 0.0 2.6 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 CDS26646.2 - 2.4e-07 30.9 0.2 0.12 12.3 0.0 3.6 2 2 2 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS26646.2 - 7.4e-07 28.8 0.0 0.042 13.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDS26646.2 - 0.00033 20.1 0.1 0.9 8.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3048_C PF17479.2 CDS26646.2 - 0.00073 19.9 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3048) C-terminal domain RIO1 PF01163.22 CDS26646.2 - 0.00084 19.0 0.0 1.9 8.0 0.0 2.8 2 0 0 2 2 2 2 RIO1 family DUF5300 PF17224.3 CDS26646.2 - 0.054 13.8 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) PHR PF08005.12 CDS26646.2 - 0.11 13.1 0.0 32 5.2 0.0 2.6 3 0 0 3 3 2 0 PHR domain SH3_10 PF17902.1 CDS26646.2 - 0.12 12.5 0.0 0.44 10.7 0.0 2.0 1 0 0 1 1 1 0 SH3 domain RcbX PF02341.15 CDS26646.2 - 0.17 12.2 0.2 32 4.8 0.0 2.4 2 0 0 2 2 2 0 RbcX protein Pox_A12 PF04651.13 CDS26647.1 - 0.0066 16.5 10.1 0.0067 16.5 10.1 1.1 1 0 0 1 1 1 1 Poxvirus A12 protein DDHD PF02862.17 CDS26647.1 - 0.13 12.4 9.2 0.14 12.3 9.2 1.0 1 0 0 1 1 1 0 DDHD domain MDFI PF15316.6 CDS26647.1 - 4.1 7.5 8.7 4.2 7.4 8.7 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Presenilin PF01080.17 CDS26647.1 - 5.6 5.6 9.2 5.5 5.6 9.2 1.0 1 0 0 1 1 1 0 Presenilin UbiA PF01040.18 CDS26648.1 - 7.8e-46 156.4 19.3 1.1e-45 155.9 19.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UPF0016 PF01169.19 CDS26648.1 - 3.3 8.1 9.5 0.22 11.9 2.7 2.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 ELP6 PF09807.9 CDS26649.1 - 3.6e-07 29.9 0.1 8.4e-07 28.7 0.1 1.6 1 1 0 1 1 1 1 Elongation complex protein 6 ATPase_2 PF01637.18 CDS26649.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LSDAT_euk PF18139.1 CDS26650.2 - 6.4e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM Ank_2 PF12796.7 CDS26650.2 - 4.9e-08 33.5 0.5 5e-07 30.2 0.3 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ion_trans PF00520.31 CDS26650.2 - 6.5e-08 32.1 21.6 1.3e-07 31.1 21.6 1.5 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 CDS26650.2 - 7.1e-06 26.5 0.3 8.8e-05 23.0 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDS26650.2 - 0.00073 19.9 0.5 1.2 9.7 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 CDS26650.2 - 0.00083 19.6 3.0 0.24 12.1 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat LSDAT_prok PF18171.1 CDS26650.2 - 0.0036 16.6 0.0 0.092 12.0 0.0 2.4 2 0 0 2 2 2 1 SLOG in TRPM, prokaryote Ank_5 PF13857.6 CDS26650.2 - 0.046 14.1 0.4 0.94 9.9 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) SRCR PF00530.18 CDS26652.1 - 8.9e-25 87.1 2.6 1.8e-13 50.9 0.8 3.1 2 1 0 2 2 2 2 Scavenger receptor cysteine-rich domain Zona_pellucida PF00100.23 CDS26652.1 - 5.2e-18 65.8 1.5 6.9e-18 65.4 1.5 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR_2 PF15494.6 CDS26652.1 - 4.7e-09 36.7 0.2 0.00043 20.8 0.1 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain DUF4602 PF15375.6 CDS26653.1 - 1e-09 38.8 12.0 2.8e-09 37.4 10.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) Dynein_light PF01221.18 CDS26654.1 - 1.2e-21 76.8 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 HMG_box PF00505.19 CDS26655.1 - 6.9e-19 68.0 3.4 1.4e-18 67.1 3.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS26655.1 - 4.7e-09 36.7 1.1 1.2e-08 35.4 1.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF4179 PF13786.6 CDS26655.1 - 7.6 7.1 0.0 7.6 7.1 0.0 5.3 5 2 0 5 5 5 0 Domain of unknown function (DUF4179) SNARE PF05739.19 CDS26656.1 - 1.1e-12 47.7 1.1 1.1e-12 47.7 1.1 2.2 2 0 0 2 2 2 1 SNARE domain SKA1 PF07160.12 CDS26656.1 - 0.00037 20.4 9.9 0.062 13.1 2.5 2.1 2 0 0 2 2 2 2 Spindle and kinetochore-associated protein 1 ABC_tran_CTD PF16326.5 CDS26656.1 - 0.00076 19.7 7.4 0.0093 16.2 0.3 2.9 2 1 0 3 3 3 1 ABC transporter C-terminal domain DUF4988 PF16378.5 CDS26656.1 - 0.008 15.9 3.1 0.22 11.2 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function Abhydrolase_8 PF06259.12 CDS26656.1 - 0.013 15.1 1.0 0.025 14.2 0.6 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase K_channel_TID PF07941.11 CDS26656.1 - 0.02 15.4 2.8 0.02 15.4 2.8 1.7 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain End3 PF12761.7 CDS26656.1 - 0.022 15.0 8.1 0.11 12.7 0.2 2.9 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 EzrA PF06160.12 CDS26656.1 - 0.026 12.7 0.4 0.026 12.7 0.4 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA VWA_2 PF13519.6 CDS26656.1 - 0.028 15.0 4.2 2.9 8.6 0.3 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain CCDC-167 PF15188.6 CDS26656.1 - 0.029 14.7 0.4 0.029 14.7 0.4 2.7 4 0 0 4 4 2 0 Coiled-coil domain-containing protein 167 P4Ha_N PF08336.11 CDS26656.1 - 0.035 14.1 2.8 0.14 12.2 0.4 2.5 2 2 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region WDCP PF15390.6 CDS26656.1 - 0.038 12.4 6.6 0.093 11.1 6.6 1.5 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family FliJ PF02050.16 CDS26656.1 - 0.048 13.9 0.1 0.048 13.9 0.1 2.9 3 1 0 3 3 3 0 Flagellar FliJ protein YkyA PF10368.9 CDS26656.1 - 0.054 13.2 6.7 0.24 11.0 0.1 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF4315 PF14193.6 CDS26656.1 - 0.075 13.1 2.7 0.13 12.3 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) YnfE PF17452.2 CDS26656.1 - 0.08 13.2 0.8 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized YnfE-like Syntaxin PF00804.25 CDS26656.1 - 0.09 12.4 11.5 0.99 9.0 3.2 2.9 2 1 0 2 2 2 0 Syntaxin TMF_TATA_bd PF12325.8 CDS26656.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.7 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 CDS26656.1 - 0.16 12.4 7.8 0.077 13.5 1.0 2.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein VIT1 PF01988.19 CDS26656.1 - 0.29 11.0 3.1 0.2 11.5 0.2 1.9 2 0 0 2 2 2 0 VIT family DASH_Dad2 PF08654.10 CDS26656.1 - 0.29 11.6 7.2 0.57 10.6 3.2 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad2 Syntaxin_2 PF14523.6 CDS26656.1 - 0.29 11.5 10.4 0.17 12.3 5.8 2.6 1 1 2 3 3 3 0 Syntaxin-like protein DUF5082 PF16888.5 CDS26656.1 - 0.29 11.4 10.4 3.9 7.8 0.2 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) XhlA PF10779.9 CDS26656.1 - 0.29 11.3 2.5 0.61 10.3 0.6 2.6 3 1 0 3 3 2 0 Haemolysin XhlA Laminin_II PF06009.12 CDS26656.1 - 2.2 8.3 12.5 0.27 11.3 4.9 2.6 2 1 0 2 2 2 0 Laminin Domain II HsbA PF12296.8 CDS26656.1 - 2.8 8.4 7.0 2 8.9 0.1 3.1 1 1 2 3 3 3 0 Hydrophobic surface binding protein A APG17 PF04108.12 CDS26656.1 - 3.8 6.5 13.5 0.67 9.0 0.7 2.4 1 1 0 2 2 2 0 Autophagy protein Apg17 DUF4200 PF13863.6 CDS26656.1 - 4 7.9 12.3 0.79 10.1 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 CDS26656.1 - 4.6 7.8 13.2 4.5 7.8 2.5 3.0 2 1 0 3 3 3 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 CDS26656.1 - 6.1 7.1 9.0 4.4 7.6 5.5 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein PI3K_P85_iSH2 PF16454.5 CDS26656.1 - 6.2 6.4 11.0 2.1e+02 1.4 11.0 3.1 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 CDS26656.1 - 7 6.7 12.7 3 7.9 0.4 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CDS26656.1 - 8.3 6.8 10.3 6.2 7.2 1.2 3.5 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RsfS PF02410.15 CDS26657.1 - 6.5e-21 74.6 0.0 9.4e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Homeodomain PF00046.29 CDS26658.1 - 4.5e-11 42.4 0.4 9.4e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Homeodomain DUF727 PF05303.12 CDS26659.1 - 2.7e-33 114.2 0.0 3.8e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Foie-gras_1 PF11817.8 CDS26659.1 - 0.04 13.5 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 Pkinase PF00069.25 CDS26660.1 - 2e-30 106.1 0.0 2.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26660.1 - 2.7e-18 66.2 0.0 3.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26660.1 - 0.024 13.4 0.0 0.055 12.2 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase DUF846 PF05832.12 CDS26661.1 - 2.4e-43 147.5 7.6 3.4e-43 147.0 7.6 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 CDS26661.1 - 0.0071 16.7 6.7 0.03 14.6 1.3 2.2 2 0 0 2 2 2 2 YwiC-like protein DUF3307 PF11750.8 CDS26661.1 - 0.0096 16.0 0.3 0.088 12.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3307) DUF1980 PF09323.10 CDS26661.1 - 0.23 11.3 0.0 0.51 10.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Evr1_Alr PF04777.13 CDS26662.1 - 9.5e-27 93.4 1.1 2e-26 92.3 1.1 1.6 1 0 0 1 1 1 1 Erv1 / Alr family LSM PF01423.22 CDS26662.1 - 5.3e-08 32.4 0.0 8.8e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 LSM domain Kinesin PF00225.23 CDS26663.1 - 3.6e-69 233.2 0.5 5.4e-69 232.7 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 CDS26663.1 - 1.1e-35 121.9 0.2 1e-34 118.8 0.0 2.6 3 0 0 3 3 3 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Spore_III_AB PF09548.10 CDS26663.1 - 0.39 10.8 2.6 0.81 9.8 2.6 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SRF-TF PF00319.18 CDS26664.1 - 5e-23 80.3 0.3 7.7e-23 79.7 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UQ_con PF00179.26 CDS26666.1 - 2.7e-45 153.5 0.0 5.2e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NCD2 PF04905.13 CDS26666.1 - 1.6e-20 73.3 0.2 2e-08 34.2 0.1 3.7 4 0 0 4 4 4 2 NAB conserved region 2 (NCD2) LRR_8 PF13855.6 CDS26666.1 - 2.8e-05 23.8 0.3 0.00012 21.7 0.2 2.2 2 0 0 2 2 2 1 Leucine rich repeat WD40 PF00400.32 CDS26666.1 - 0.0038 18.0 0.0 0.44 11.5 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat LRR_4 PF12799.7 CDS26666.1 - 0.042 14.3 11.2 0.066 13.7 4.9 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) RWD PF05773.22 CDS26666.1 - 0.11 12.8 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 RWD domain LRR_1 PF00560.33 CDS26666.1 - 0.47 11.2 5.5 26 5.9 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Inos-1-P_synth PF01658.17 CDS26667.1 - 0.066 13.5 0.0 0.14 12.4 0.0 1.5 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase COesterase PF00135.28 CDS26668.1 - 5.8e-99 332.3 0.0 7.4e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 CDS26668.1 - 2.5e-07 29.9 0.5 8.4e-07 28.2 0.5 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CDS26668.1 - 2.6e-07 30.7 0.1 6e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDS26668.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family ANAPC4_WD40 PF12894.7 CDS26670.1 - 3.2e-09 36.9 0.0 0.00089 19.5 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS26670.1 - 4.2e-05 24.2 3.7 1.5 9.8 0.0 5.3 4 1 1 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.11 CDS26670.1 - 0.00066 19.6 0.0 0.74 9.7 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CDS26670.1 - 0.056 13.4 2.2 4.2 7.4 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HA2 PF04408.23 CDS26671.1 - 6.1e-24 84.4 0.2 6.1e-24 84.4 0.2 3.4 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDS26671.1 - 6.8e-24 84.1 0.0 1.8e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDS26671.1 - 5e-13 49.4 0.0 1.5e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CDS26671.1 - 3.3e-09 37.0 0.0 1.5e-08 34.8 0.0 2.2 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CDS26671.1 - 7.8e-07 29.0 0.1 2.4e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDS26671.1 - 5.2e-06 26.8 1.1 0.00016 21.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CDS26671.1 - 6.2e-05 22.2 1.1 0.0011 18.1 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CDS26671.1 - 0.0013 19.1 0.2 0.0087 16.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CDS26671.1 - 0.052 13.4 0.0 0.74 9.6 0.0 2.7 2 1 1 3 3 3 0 Helicase AAA_7 PF12775.7 CDS26671.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CDS26671.1 - 0.067 13.1 0.3 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CDS26671.1 - 0.07 13.5 0.2 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 CDS26671.1 - 0.078 12.4 0.1 0.22 10.9 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CDS26671.1 - 0.27 11.8 3.7 0.37 11.3 0.7 2.7 2 1 0 2 2 1 0 ABC transporter CaMBD PF02888.16 CDS26673.2 - 3.3e-35 120.1 5.6 6.8e-35 119.1 5.6 1.6 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CDS26673.2 - 1.9e-11 43.8 5.0 1.9e-11 43.8 5.0 1.9 1 1 1 2 2 2 1 Ion channel Ion_trans PF00520.31 CDS26673.2 - 0.0039 16.5 3.9 0.0058 15.9 3.9 1.2 1 0 0 1 1 1 1 Ion transport protein RUN PF02759.19 CDS26674.1 - 2.3e-05 24.4 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RUN domain DUF2203 PF09969.9 CDS26675.1 - 0.027 15.2 0.0 0.049 14.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NIF3 PF01784.18 CDS26676.1 - 1.3e-66 224.7 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NIF3 PF01784.18 CDS26677.2 - 1.3e-66 224.7 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HA2 PF04408.23 CDS26678.1 - 3.7e-20 72.2 0.1 3.7e-20 72.2 0.1 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDS26678.1 - 4e-12 46.5 0.0 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDS26678.1 - 1.6e-11 44.4 0.0 5.6e-11 42.6 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDS26678.1 - 2.3e-09 37.3 0.9 5.9e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDS26678.1 - 1.5e-05 25.3 0.2 0.0078 16.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 CDS26678.1 - 0.00045 20.6 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDS26678.1 - 0.00095 18.9 0.1 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDS26678.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 KaiC FtsK_SpoIIIE PF01580.18 CDS26678.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 CDS26678.1 - 0.024 13.7 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 CDS26678.1 - 0.06 12.3 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 CDS26678.1 - 0.1 12.8 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pam16 PF03656.13 CDS26679.1 - 1.6e-42 144.5 0.3 1.9e-42 144.3 0.3 1.0 1 0 0 1 1 1 1 Pam16 Integrase_Zn PF02022.19 CDS26679.1 - 0.088 12.8 0.2 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain RRM_1 PF00076.22 CDS26680.1 - 3.8e-09 36.2 0.2 1.1e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDS26680.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_2 PF14608.6 CDS26680.1 - 0.038 14.5 0.5 0.07 13.6 0.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Pox_A51 PF04948.13 CDS26680.1 - 0.05 12.4 0.2 0.082 11.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A51 protein Citrate_synt PF00285.21 CDS26683.1 - 1.5e-103 346.6 0.0 1.7e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5034 PF16437.5 CDS26683.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) PTCB-BRCT PF12738.7 CDS26684.1 - 1.3e-32 111.5 2.7 4.9e-19 68.0 0.1 5.4 5 1 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 CDS26684.1 - 1.2e-31 108.9 0.4 1.1e-10 41.7 0.1 5.9 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDS26684.1 - 1.1e-21 77.0 0.0 0.0026 18.1 0.0 6.8 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CDS26684.1 - 1.3e-09 38.0 0.1 0.38 10.8 0.0 5.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDS26684.1 - 1.8e-08 34.5 0.1 0.054 13.8 0.0 5.0 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 CDS26684.1 - 5.4e-07 29.4 0.0 0.02 14.8 0.0 4.6 4 1 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain Peptidase_S28 PF05577.12 CDS26685.1 - 6.4e-62 209.8 0.0 7.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 CDS26685.1 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CDS26685.1 - 0.025 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NIP_1 PF08995.10 CDS26685.1 - 0.065 13.6 0.3 0.13 12.7 0.3 1.5 1 0 0 1 1 1 0 Necrosis inducing protein-1 Peptidase_S37 PF05576.11 CDS26685.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 Pkinase PF00069.25 CDS26686.1 - 3.3e-74 249.6 0.0 5.8e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26686.1 - 7.3e-40 136.9 0.0 1.2e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26686.1 - 0.00016 21.1 0.0 0.0014 18.0 0.0 2.2 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 CDS26686.1 - 0.0037 17.2 0.5 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS26686.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CDS26686.1 - 0.049 12.6 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain HEAT PF02985.22 CDS26686.1 - 0.089 13.1 0.1 21 5.7 0.0 3.9 2 0 0 2 2 2 0 HEAT repeat FTA2 PF13095.6 CDS26686.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDS26686.1 - 0.17 11.2 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_EZ PF13513.6 CDS26686.1 - 0.46 11.0 9.6 2.5 8.7 0.1 6.1 6 1 0 6 6 6 0 HEAT-like repeat DDRGK PF09756.9 CDS26687.1 - 3e-51 173.7 24.8 3e-51 173.7 24.8 1.9 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.27 CDS26687.1 - 0.0079 16.7 0.1 0.02 15.4 0.1 1.6 1 1 1 2 2 2 1 PCI domain Nop53 PF07767.11 CDS26687.1 - 0.074 12.4 35.4 0.098 12.0 35.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SID-1_RNA_chan PF13965.6 CDS26687.1 - 0.18 10.2 2.1 0.27 9.6 2.1 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 T2SSM PF04612.12 CDS26687.1 - 0.22 11.6 6.8 0.22 11.6 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M NAM-associated PF14303.6 CDS26687.1 - 0.49 11.1 22.4 0.8 10.4 22.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Neur_chan_memb PF02932.16 CDS26687.1 - 2.2 8.3 5.7 3.7 7.5 5.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 CDS26687.1 - 4.8 7.2 19.3 7.7 6.5 19.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 CDS26687.1 - 5.1 5.1 11.1 6.6 4.7 11.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4692 PF15763.5 CDS26687.1 - 5.1 7.5 8.7 0.61 10.5 3.2 2.0 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) zf-RING_2 PF13639.6 CDS26688.1 - 2.7e-10 40.4 13.9 2.7e-10 40.4 13.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS26688.1 - 3.9e-06 26.6 8.0 3.9e-06 26.6 8.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS26688.1 - 5.2e-05 23.0 11.5 5.2e-05 23.0 11.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDS26688.1 - 7.2e-05 22.4 4.9 7.2e-05 22.4 4.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CDS26688.1 - 9e-05 22.7 12.6 0.0003 21.0 12.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDS26688.1 - 0.00019 21.3 10.0 0.00047 20.0 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS26688.1 - 0.0003 20.7 8.2 0.001 19.0 8.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDS26688.1 - 0.00032 20.6 8.0 0.00032 20.6 8.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain CUE PF02845.16 CDS26688.1 - 0.0011 18.6 0.1 0.01 15.5 0.0 2.4 2 0 0 2 2 2 1 CUE domain zf-ANAPC11 PF12861.7 CDS26688.1 - 0.0039 17.2 5.0 0.0097 15.9 5.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDS26688.1 - 0.01 15.5 8.7 0.023 14.3 8.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDS26688.1 - 0.98 9.3 15.0 0.08 12.8 10.0 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDS26688.1 - 2.6 7.9 9.0 9.2 6.2 9.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4131 PF13567.6 CDS26688.1 - 3.7 7.2 5.4 0.62 9.7 0.6 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 CDS26689.1 - 3.1e-27 95.8 4.8 3.7e-27 95.5 4.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1218 PF06749.12 CDS26689.1 - 0.1 13.2 7.3 10 6.7 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DUF3043 PF11241.8 CDS26689.1 - 0.68 10.0 1.8 1.2 9.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF2892 PF11127.8 CDS26689.1 - 6 7.0 12.2 1.6 8.8 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) COesterase PF00135.28 CDS26690.1 - 5.6e-92 309.2 0.1 6.6e-92 309.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS26690.1 - 3.3e-09 36.9 0.1 1e-08 35.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDS26690.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 CDS26691.1 - 9.5e-35 120.4 0.0 1.4e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Arf PF00025.21 CDS26692.1 - 3.3e-61 205.8 0.0 3.9e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS26692.1 - 1.3e-14 54.5 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS26692.1 - 3e-13 49.7 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDS26692.1 - 2.4e-08 33.5 0.1 0.00012 21.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDS26692.1 - 5.5e-08 32.5 0.0 6.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS26692.1 - 8.4e-08 31.9 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDS26692.1 - 7.7e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 CDS26692.1 - 0.0019 17.8 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CDS26692.1 - 0.0073 15.9 0.0 0.027 14.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDS26692.1 - 0.038 13.5 0.1 0.099 12.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 CDS26692.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDS26692.1 - 0.13 12.8 0.0 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter rve PF00665.26 CDS26693.1 - 0.046 13.9 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.6 CDS26693.1 - 0.048 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Ribosomal_L7Ae PF01248.26 CDS26695.1 - 5.4e-26 90.2 0.1 6.4e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CDS26695.1 - 2.5e-05 24.4 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CDS26695.1 - 0.013 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain baeRF_family2 PF18844.1 CDS26695.1 - 0.055 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 DUF2207 PF09972.9 CDS26696.1 - 1.4 7.6 4.1 0.99 8.1 2.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) QVR PF17064.5 CDS26697.1 - 1.6e-12 47.5 0.2 2.5e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Sleepless protein SNase PF00565.17 CDS26698.1 - 8.9e-55 183.8 0.0 2.2e-12 47.4 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CDS26698.1 - 5.9e-12 45.7 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 CDS26698.1 - 0.18 12.3 0.5 7.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Agenet domain DUF4834 PF16118.5 CDS26699.1 - 9.2e-05 23.3 0.7 0.00013 22.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TMEM154 PF15102.6 CDS26699.1 - 0.0065 16.4 0.9 0.0065 16.4 0.9 2.1 1 1 1 2 2 2 1 TMEM154 protein family Cadherin_C_2 PF16492.5 CDS26699.1 - 0.027 15.2 0.0 0.038 14.7 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal PDZ PF00595.24 CDS26700.1 - 2.5e-22 79.0 0.5 3.6e-22 78.5 0.5 1.2 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 CDS26700.1 - 8.6e-17 60.7 0.3 1.8e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 CDS26700.1 - 1.5e-12 47.1 0.6 3.6e-12 46.0 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDS26700.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain TB2_DP1_HVA22 PF03134.19 CDS26701.1 - 1.2e-27 95.7 3.2 1.5e-27 95.3 3.2 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4512 PF14975.6 CDS26701.1 - 0.032 15.0 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) LANC_like PF05147.13 CDS26702.1 - 2.6e-52 177.5 0.0 3.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein WD40 PF00400.32 CDS26702.1 - 1.9e-05 25.3 7.3 0.23 12.4 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_hydro_88 PF07470.13 CDS26702.1 - 0.002 17.3 0.0 0.0056 15.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 CDS26702.1 - 0.0037 16.8 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 CDS26702.1 - 0.031 12.8 0.1 0.85 8.0 0.2 2.0 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 CDS26702.1 - 0.053 12.8 0.0 7.7 5.6 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) zf-C3HC4_2 PF13923.6 CDS26703.1 - 7e-09 35.4 8.2 3.5e-08 33.2 8.2 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT_2 PF16589.5 CDS26703.1 - 8.7e-09 35.7 0.0 0.00011 22.5 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_3 PF13920.6 CDS26703.1 - 5e-08 32.7 7.5 5e-08 32.7 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS26703.1 - 1e-07 31.7 8.2 1e-07 31.7 8.2 2.5 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CDS26703.1 - 2.2e-07 30.6 9.7 2.2e-07 30.6 9.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS26703.1 - 2.3e-07 31.0 9.5 2.3e-07 31.0 9.5 2.3 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS26703.1 - 2.5e-06 27.4 9.9 2.5e-06 27.4 9.9 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDS26703.1 - 3.8e-06 26.8 8.4 3.8e-06 26.8 8.4 2.7 3 0 0 3 3 2 1 zinc-RING finger domain BRCT PF00533.26 CDS26703.1 - 2.4e-05 24.6 0.0 0.0024 18.2 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RING_11 PF17123.5 CDS26703.1 - 0.0044 16.7 1.8 0.0044 16.7 1.8 2.8 2 1 0 2 2 2 1 RING-like zinc finger RTT107_BRCT_5 PF16770.5 CDS26703.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_4 PF14570.6 CDS26703.1 - 0.013 15.3 6.0 0.038 13.8 6.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CDS26703.1 - 0.013 15.6 12.5 0.015 15.5 9.8 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDS26703.1 - 0.031 14.6 4.8 0.12 12.7 4.8 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn-C2H2_12 PF18112.1 CDS26703.1 - 0.094 13.2 5.0 0.12 12.9 0.6 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain TerY_C PF15616.6 CDS26703.1 - 0.28 11.3 2.5 0.82 9.8 2.5 1.8 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C2H2_6 PF13912.6 CDS26703.1 - 0.32 11.0 1.9 9.7 6.3 0.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_6 PF14835.6 CDS26703.1 - 0.79 9.6 3.4 2.4 8.1 3.4 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 CDS26703.1 - 6.3 6.9 8.2 11 6.1 4.8 2.7 2 0 0 2 2 2 0 zinc-ribbons zf-P11 PF03854.14 CDS26703.1 - 7.3 6.3 12.9 2.6 7.8 7.8 2.6 2 1 1 3 3 3 0 P-11 zinc finger Nif11 PF07862.11 CDS26704.1 - 0.044 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 Nif11 domain Sec1 PF00995.23 CDS26705.1 - 5.7e-122 408.8 0.8 6.5e-122 408.6 0.8 1.0 1 0 0 1 1 1 1 Sec1 family DUF438 PF04282.13 CDS26705.1 - 1.8 8.6 4.8 7.1 6.7 0.1 3.7 5 0 0 5 5 5 0 Family of unknown function (DUF438) DEAD PF00270.29 CDS26707.1 - 1.8e-16 60.4 0.0 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS26707.1 - 1.5e-15 57.5 0.0 1.4e-11 44.8 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDS26707.1 - 1.7e-10 41.5 1.8 6e-10 39.7 1.8 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CDS26707.1 - 0.00075 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ExoD PF06055.12 CDS26707.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD TraC PF07820.12 CDS26707.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 TraC-like protein SRI PF08236.11 CDS26707.1 - 0.16 12.1 0.7 1.3 9.3 0.0 2.9 3 1 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain DHO_dh PF01180.21 CDS26708.1 - 9.2e-34 117.0 0.0 1.3e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 CDS26708.1 - 1.7e-29 101.8 0.2 1.7e-29 101.8 0.2 3.3 2 1 1 3 3 3 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 CDS26708.1 - 5.2e-22 77.7 8.7 5.2e-22 77.7 8.7 3.7 4 1 0 4 4 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 CDS26708.1 - 1.2e-14 54.3 0.0 3.5e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDS26708.1 - 1.7e-09 37.4 0.0 2.3e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDS26708.1 - 3.3e-08 34.0 0.0 0.0025 18.3 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDS26708.1 - 6e-06 26.4 0.0 1.8e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 CDS26708.1 - 1.1e-05 25.5 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Fer4_9 PF13187.6 CDS26708.1 - 2.4e-05 24.4 8.7 2.4e-05 24.4 8.7 3.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CDS26708.1 - 3e-05 24.5 10.7 3e-05 24.5 10.7 3.7 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDS26708.1 - 0.00013 21.8 28.1 0.00041 20.3 1.4 4.8 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 CDS26708.1 - 0.00031 20.8 27.1 0.012 15.7 12.6 3.7 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 CDS26708.1 - 0.0041 17.6 16.1 0.29 11.7 0.2 4.2 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDS26708.1 - 0.0046 17.0 31.1 0.17 12.0 2.5 5.1 4 0 0 4 4 4 3 4Fe-4S binding domain NAD_binding_7 PF13241.6 CDS26708.1 - 0.0063 16.9 0.0 0.061 13.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CDS26708.1 - 0.011 15.0 0.0 0.037 13.3 0.0 1.9 2 0 0 2 2 2 0 Thi4 family PALP PF00291.25 CDS26708.1 - 0.013 15.0 0.1 1 8.7 0.2 2.3 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme FAD_oxidored PF12831.7 CDS26708.1 - 0.054 12.8 0.3 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Dus PF01207.17 CDS26708.1 - 0.081 12.0 0.0 0.56 9.3 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) AlaDh_PNT_C PF01262.21 CDS26708.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 CDS26708.1 - 0.23 10.5 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_18 PF13746.6 CDS26708.1 - 0.26 11.5 14.5 0.78 10.0 1.3 3.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4 PF00037.27 CDS26708.1 - 1.1 9.1 31.5 0.016 15.0 3.8 4.5 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4_8 PF13183.6 CDS26708.1 - 1.8 9.1 24.4 0.54 10.7 1.5 3.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CDS26708.1 - 3.4 8.4 29.9 0.14 12.7 3.3 4.6 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 CDS26708.1 - 7.6 7.5 22.6 0.89 10.5 1.8 4.6 3 1 2 5 5 5 0 4Fe-4S double cluster binding domain Ribosomal_L24e PF01246.20 CDS26709.1 - 9.4e-28 96.2 7.4 9.4e-28 96.2 7.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e ABC1 PF03109.16 CDS26709.1 - 0.76 10.0 4.9 0.58 10.3 2.7 1.8 1 1 0 2 2 2 0 ABC1 family RWD PF05773.22 CDS26710.1 - 3.8e-15 56.2 0.3 6e-15 55.6 0.3 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 CDS26710.1 - 0.074 12.7 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme DIM1 PF02966.16 CDS26711.1 - 6.2e-62 207.2 0.1 9.7e-62 206.6 0.1 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 OTU PF02338.19 CDS26711.1 - 3e-18 66.5 0.0 5.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Thioredoxin PF00085.20 CDS26711.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Thioredox_DsbH PF03190.15 CDS26711.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF2428 PF10350.9 CDS26712.1 - 3e-62 210.4 0.1 1e-61 208.7 0.1 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CDS26712.1 - 1.8 9.1 7.2 7.2 7.2 0.3 5.0 5 0 0 5 5 5 0 HEAT repeat TTL PF03133.15 CDS26713.1 - 8.4e-83 277.9 0.3 1.5e-82 277.0 0.3 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Mito_carr PF00153.27 CDS26713.1 - 1.3e-66 220.6 2.4 4.1e-23 81.1 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CDS26713.1 - 5.3e-13 49.2 3.6 3.6e-07 30.5 0.9 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS26713.1 - 9.7e-13 46.9 0.7 0.00024 20.8 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDS26713.1 - 3.3e-10 38.8 7.9 0.0056 16.1 0.0 4.5 5 0 0 5 5 4 3 EF hand EF-hand_5 PF13202.6 CDS26713.1 - 9.8e-10 37.5 2.0 0.001 18.5 0.0 3.3 3 0 0 3 3 3 2 EF hand ATPgrasp_YheCD PF14398.6 CDS26713.1 - 3e-06 26.7 0.6 0.00091 18.5 0.0 3.2 3 1 0 3 3 3 1 YheC/D like ATP-grasp SPARC_Ca_bdg PF10591.9 CDS26713.1 - 3.6e-05 24.1 1.7 0.0026 18.0 0.7 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region ATPgrasp_ST PF14397.6 CDS26713.1 - 0.00013 21.3 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CDS26713.1 - 0.00025 21.1 0.0 0.03 14.4 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain EF-hand_8 PF13833.6 CDS26713.1 - 0.00065 19.5 2.0 1.5 8.7 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair RimK PF08443.11 CDS26713.1 - 0.082 12.5 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Arm-DNA-bind_5 PF17293.2 CDS26713.1 - 0.15 12.5 3.0 0.21 12.0 0.4 2.7 2 0 0 2 2 2 0 Arm DNA-binding domain TM231 PF10149.9 CDS26713.1 - 1.6 8.0 3.7 0.54 9.5 0.1 2.0 3 0 0 3 3 3 0 Transmembrane protein 231 Amidohydro_3 PF07969.11 CDS26714.1 - 1.5e-17 64.2 0.3 2e-12 47.4 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 CDS26714.1 - 6.4e-16 58.6 0.0 5.3e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family MR_MLE_C PF13378.6 CDS26714.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Enolase C-terminal domain-like Galactosyl_T PF01762.21 CDS26715.1 - 6.3e-31 107.7 0.1 2.9e-25 89.2 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Bromodomain PF00439.25 CDS26715.1 - 0.08 13.0 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Bromodomain POP1 PF06978.11 CDS26716.1 - 1e-24 87.7 9.7 2.4e-16 60.4 0.2 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 HECT PF00632.25 CDS26717.2 - 3.6e-86 289.4 0.0 4.4e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC5 PF12862.7 CDS26718.1 - 0.011 15.7 1.0 0.25 11.4 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 CDS26718.1 - 0.074 13.3 8.1 2.9 8.3 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDS26718.1 - 0.082 13.3 0.4 9.4 6.7 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDS26718.1 - 1.9 9.2 5.8 2.3 8.9 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ig_3 PF13927.6 CDS26719.1 - 2.2e-15 57.0 1.1 0.00015 22.3 0.0 5.4 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDS26719.1 - 2.4e-11 43.6 0.9 0.51 10.5 0.0 6.4 5 2 1 6 6 6 4 Immunoglobulin domain V-set PF07686.17 CDS26719.1 - 3.1e-11 43.4 0.0 0.0031 17.7 0.0 5.0 4 1 0 4 4 4 2 Immunoglobulin V-set domain I-set PF07679.16 CDS26719.1 - 2.3e-10 40.4 0.0 0.016 15.3 0.0 4.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_6 PF18452.1 CDS26719.1 - 7.1e-06 25.5 0.0 0.25 10.9 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 CDS26719.1 - 8.1e-06 26.1 0.2 4.6 7.6 0.0 5.4 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 CDS26719.1 - 0.056 13.5 0.1 11 6.2 0.0 3.3 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain DUF4448 PF14610.6 CDS26719.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Endosulfine PF04667.17 CDS26720.1 - 3.3e-08 33.6 0.6 5.1e-08 32.9 0.6 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region TFIID-31kDa PF02291.15 CDS26721.1 - 1.6e-26 92.8 0.0 2.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit 2-Hacid_dh_C PF02826.19 CDS26722.1 - 3e-13 49.5 0.0 6.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THAP PF05485.12 CDS26722.1 - 6.3e-09 36.6 0.0 1.6e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 THAP domain EST1_DNA_bind PF10373.9 CDS26723.2 - 1.2e-05 25.0 1.3 0.00012 21.7 0.1 2.7 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 CDS26723.2 - 0.00084 19.6 2.6 0.00099 19.4 0.0 2.3 2 0 0 2 2 2 1 PIN domain Cadherin PF00028.17 CDS26724.2 - 2.2e-67 223.6 1.1 2.2e-13 50.5 0.0 8.0 6 3 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 CDS26724.2 - 2.2e-07 30.6 1.0 0.089 12.6 0.0 5.4 5 0 0 5 5 5 1 Cadherin-like Cadherin_3 PF16184.5 CDS26724.2 - 0.022 14.7 3.5 3.9 7.5 0.0 5.0 5 1 0 5 5 5 0 Cadherin-like RET_CLD1 PF17756.1 CDS26724.2 - 0.1 12.9 0.0 17 5.7 0.0 3.5 3 0 0 3 3 3 0 RET Cadherin like domain 1 LapA_dom PF06305.11 CDS26724.2 - 0.24 11.2 0.5 0.43 10.4 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PH PF00169.29 CDS26726.1 - 5.7e-15 55.7 1.5 9.9e-15 54.9 0.1 2.2 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 CDS26726.1 - 0.0044 17.4 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain LRR_8 PF13855.6 CDS26727.1 - 5.2e-14 51.8 18.0 6.9e-08 32.1 1.1 3.2 1 1 3 4 4 4 3 Leucine rich repeat zf-C3HC4_3 PF13920.6 CDS26727.1 - 4.2e-09 36.1 23.5 8e-09 35.2 23.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 CDS26727.1 - 7.6e-09 35.7 6.4 0.0018 18.6 0.2 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) SAM_1 PF00536.30 CDS26727.1 - 5.4e-07 30.0 0.0 2.2e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS26727.1 - 7.4e-07 29.2 0.0 4.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 CDS26727.1 - 2e-05 24.5 7.5 18 6.4 0.1 6.5 5 1 0 5 5 5 2 Leucine Rich Repeat SHOCT PF09851.9 CDS26727.1 - 0.0079 15.9 0.6 0.075 12.8 0.1 3.0 3 0 0 3 3 3 1 Short C-terminal domain LRR_6 PF13516.6 CDS26727.1 - 0.23 11.6 3.9 3.6 7.9 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Prok-RING_4 PF14447.6 CDS26727.1 - 1.7 8.5 23.1 3.7 7.5 23.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.25 CDS26728.1 - 1.7e-24 86.6 0.0 2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26728.1 - 1.7e-12 47.2 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26728.1 - 4.7e-08 32.2 0.0 6.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS26728.1 - 0.00086 19.3 0.0 0.077 12.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 CDS26728.1 - 0.012 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pox_ser-thr_kin PF05445.11 CDS26728.1 - 0.032 13.2 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PTPS PF01242.19 CDS26729.1 - 4e-28 97.9 0.1 4.5e-28 97.7 0.1 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Radial_spoke PF04712.12 CDS26730.1 - 7.6e-49 167.0 0.4 7.6e-49 167.0 0.4 1.5 2 0 0 2 2 2 1 Radial spokehead-like protein TolB_like PF15869.5 CDS26730.1 - 0.099 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like DUF3698 PF12479.8 CDS26730.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Pkinase PF00069.25 CDS26731.1 - 4.7e-16 58.9 0.0 6.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26731.1 - 8.1e-10 38.4 0.0 9.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26731.1 - 1.3e-09 37.4 0.0 1.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS26731.1 - 0.0087 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SH2_2 PF14633.6 CDS26732.1 - 4.3e-61 206.1 0.7 1.1e-60 204.8 0.7 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 CDS26732.1 - 2.6e-26 92.0 0.0 6.3e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDS26732.1 - 3.2e-20 72.4 0.0 7.5e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 CDS26732.1 - 3.3e-11 43.6 4.9 1.2e-10 41.9 4.9 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CDS26732.1 - 2.8e-08 34.2 13.2 2.8e-08 34.2 13.2 6.2 3 1 3 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 CDS26732.1 - 3.3e-08 34.3 1.3 1.3e-07 32.4 1.3 2.2 1 0 0 1 1 1 1 HHH domain Tex_N PF09371.10 CDS26732.1 - 5.8e-08 32.6 0.1 0.0077 15.9 0.0 2.7 2 0 0 2 2 2 2 Tex-like protein N-terminal domain HHH_3 PF12836.7 CDS26732.1 - 1.3e-06 28.6 0.0 1.5e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 CDS26732.1 - 0.0002 21.8 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain S1 PF00575.23 CDS26732.1 - 0.00091 19.5 0.1 0.0028 18.0 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SpoIIE PF07228.12 CDS26733.1 - 8e-08 32.4 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDS26733.1 - 0.0021 17.7 0.1 0.028 14.1 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CDS26733.1 - 0.17 11.5 0.2 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C Cadherin PF00028.17 CDS26734.1 - 5.5e-69 228.7 3.0 1.5e-15 57.4 0.0 8.2 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS26734.1 - 7e-18 64.2 0.0 5e-10 39.1 0.0 4.9 4 0 0 4 4 4 4 Cadherin-like Cadherin_3 PF16184.5 CDS26734.1 - 0.37 10.8 21.9 3.7 7.6 0.0 7.6 8 1 1 9 9 9 0 Cadherin-like DUF924 PF06041.11 CDS26735.1 - 0.061 13.5 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Arteri_nsp7a PF16749.5 CDS26735.1 - 0.16 12.2 0.2 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha P2X_receptor PF00864.19 CDS26736.1 - 5.4e-88 295.5 3.3 1.6e-51 175.5 1.5 2.2 2 0 0 2 2 2 2 ATP P2X receptor WAP PF00095.21 CDS26736.1 - 1 9.8 6.0 0.1 13.0 0.7 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' SET PF00856.28 CDS26739.1 - 4.1e-10 40.3 0.2 1.5e-08 35.2 0.2 2.3 1 1 0 1 1 1 1 SET domain SVIP PF15811.5 CDS26740.1 - 9.7e-19 67.6 5.7 1.1e-18 67.4 5.7 1.1 1 0 0 1 1 1 1 Small VCP/p97-interacting protein His_Phos_2 PF00328.22 CDS26741.1 - 9.1e-16 58.2 0.4 5.5e-09 35.8 0.1 3.2 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) CoA_transf_3 PF02515.17 CDS26742.1 - 1.2e-46 159.5 0.0 3e-46 158.2 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Aph-1 PF06105.12 CDS26743.1 - 3.4e-54 183.7 18.7 4.5e-54 183.3 18.7 1.1 1 0 0 1 1 1 1 Aph-1 protein Peptidase_M14 PF00246.24 CDS26744.2 - 2.7e-72 244.0 0.0 3.7e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDS26744.2 - 4e-08 33.5 0.0 1.8e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 CDS26745.2 - 7.7e-75 252.4 0.0 9.7e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CDS26745.2 - 6.4e-06 26.5 0.0 4.1e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Carboxypeptidase activation peptide ORF6N PF10543.9 CDS26745.2 - 0.29 11.4 1.6 14 6.0 1.6 2.5 1 1 0 1 1 1 0 ORF6N domain zf-RVT PF13966.6 CDS26746.1 - 0.0046 17.6 0.8 0.0065 17.2 0.8 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Sporozoite_P67 PF05642.11 CDS26747.1 - 0.16 10.1 8.8 0.19 9.8 8.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 CDS26748.1 - 0.00031 19.8 0.1 0.00038 19.5 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2463 PF09591.10 CDS26748.1 - 0.019 14.8 3.4 0.027 14.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Amino_oxidase PF01593.24 CDS26749.1 - 5.2e-54 184.2 0.0 7.9e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDS26749.1 - 4.8e-17 62.0 0.0 1.2e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDS26749.1 - 2.3e-06 27.1 0.3 3.2e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CDS26749.1 - 2e-05 24.4 2.7 3.7e-05 23.5 2.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDS26749.1 - 5.7e-05 22.4 2.3 0.00011 21.5 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDS26749.1 - 0.00014 21.2 0.3 0.00079 18.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDS26749.1 - 0.00015 20.6 0.2 0.00026 19.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CDS26749.1 - 0.00027 20.4 2.7 0.00027 20.4 1.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDS26749.1 - 0.00036 21.0 1.0 0.00082 19.9 1.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDS26749.1 - 0.00055 19.3 0.5 0.00081 18.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CDS26749.1 - 0.0036 16.6 1.3 0.018 14.3 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CDS26749.1 - 0.0081 14.6 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 CDS26749.1 - 0.014 14.5 0.6 0.021 13.9 0.6 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDS26749.1 - 0.021 14.1 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 CDS26749.1 - 0.071 13.1 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 CDS26749.1 - 0.081 12.0 0.5 0.14 11.2 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 CDS26749.1 - 0.2 10.4 0.1 0.29 9.9 0.1 1.1 1 0 0 1 1 1 0 MCRA family Xpo1 PF08389.12 CDS26750.1 - 1.2e-14 54.6 4.6 3.9e-14 52.9 1.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein Filament PF00038.21 CDS26750.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Intermediate filament protein FEZ PF07763.13 CDS26751.1 - 1e-28 100.7 0.3 2.4e-28 99.5 0.1 1.7 1 1 1 2 2 2 1 FEZ-like protein Imm27 PF15590.6 CDS26751.1 - 0.0089 15.8 0.4 0.19 11.5 0.1 2.8 3 0 0 3 3 3 1 Immunity protein 27 FTO_CTD PF12934.7 CDS26751.1 - 0.19 11.5 2.3 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 FTO C-terminal domain RNA_pol_N PF01194.17 CDS26753.1 - 2.4e-33 114.2 0.5 2.7e-33 114.0 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CDS26753.1 - 0.016 15.5 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Corona_5a PF06336.11 CDS26753.1 - 0.064 13.2 0.1 0.064 13.2 0.1 1.4 2 0 0 2 2 2 0 Coronavirus 5a protein LRR_4 PF12799.7 CDS26754.1 - 0.041 14.3 18.7 5.3 7.6 0.5 6.2 2 2 4 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS26754.1 - 4.1 7.2 13.6 4.7 7.1 0.9 5.0 3 1 2 5 5 5 0 Leucine rich repeat RNA_pol_N PF01194.17 CDS26755.1 - 8e-32 109.3 0.4 8.9e-32 109.2 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Corona_5a PF06336.11 CDS26755.1 - 0.16 11.9 1.5 0.14 12.2 0.4 1.5 1 1 0 1 1 1 0 Coronavirus 5a protein zf-C3HC4_3 PF13920.6 CDS26757.2 - 5.8e-08 32.5 5.8 5.8e-08 32.5 5.8 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS26757.2 - 1.8e-06 27.9 10.2 1.8e-06 27.9 10.2 3.5 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 CDS26757.2 - 1.9e-06 28.1 7.5 1.9e-06 28.1 7.5 3.6 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 CDS26757.2 - 3e-06 27.0 7.6 3e-06 27.0 7.6 3.6 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS26757.2 - 3.3e-06 26.9 8.1 3.3e-06 26.9 8.1 3.6 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS26757.2 - 0.00066 19.6 9.1 0.00066 19.6 9.1 4.5 2 2 1 3 3 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS26757.2 - 0.002 18.0 7.4 0.002 18.0 7.4 4.3 3 3 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDS26757.2 - 0.0039 17.3 11.4 0.0039 17.3 11.4 4.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDS26757.2 - 0.0085 15.9 3.5 0.0085 15.9 3.5 2.7 3 1 0 3 3 3 1 zf-RING of BARD1-type protein PHD PF00628.29 CDS26757.2 - 0.015 15.2 4.2 0.015 15.2 4.2 3.4 3 0 0 3 3 3 0 PHD-finger zf-RING_11 PF17123.5 CDS26757.2 - 0.043 13.6 3.0 0.043 13.6 3.0 4.5 3 2 1 4 4 3 0 RING-like zinc finger U-box PF04564.15 CDS26757.2 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CDS26757.2 - 0.97 9.3 7.9 0.25 11.2 3.9 2.1 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit NOB1_Zn_bind PF08772.11 CDS26757.2 - 4.5 7.5 9.8 0.21 11.8 1.0 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RNB PF00773.19 CDS26758.2 - 3e-86 289.7 0.3 5.4e-84 282.3 0.3 2.1 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CDS26758.2 - 5.4e-16 58.4 0.0 1.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDS26758.2 - 0.16 12.1 0.0 6.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Cold shock domain RNB PF00773.19 CDS26759.2 - 1.7e-166 553.4 0.0 5.6e-91 305.3 0.0 3.2 2 1 0 2 2 2 2 RNB domain OB_Dis3 PF17849.1 CDS26759.2 - 3.2e-23 81.5 0.0 8.3e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CDS26759.2 - 1.2e-19 70.5 0.0 2.6e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal VitD-bind_III PF09164.10 CDS26759.2 - 2.5e-05 24.2 0.1 0.47 10.5 0.0 2.8 2 0 0 2 2 2 2 Vitamin D binding protein, domain III Rrp44_CSD1 PF17216.3 CDS26759.2 - 3.3e-05 23.6 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain CysA_C_terminal PF17850.1 CDS26759.2 - 0.63 10.7 1.9 48 4.6 0.1 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain Syntaxin PF00804.25 CDS26760.1 - 5.6e-57 192.7 19.9 7.8e-57 192.2 19.9 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CDS26760.1 - 7e-16 58.0 2.4 7e-16 58.0 2.4 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CDS26760.1 - 1.2e-07 32.0 3.2 1.2e-07 32.0 3.2 2.5 2 1 0 2 2 2 1 Syntaxin-like protein Lzipper-MIP1 PF14389.6 CDS26760.1 - 0.0056 16.9 1.2 0.0056 16.9 1.2 2.2 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Flu_NS2 PF00601.19 CDS26760.1 - 0.041 14.2 1.1 0.041 14.2 1.1 2.2 1 1 0 2 2 2 0 Influenza non-structural protein (NS2) IMS PF00817.20 CDS26760.1 - 0.076 13.0 4.0 0.46 10.5 4.0 2.1 1 1 0 1 1 1 0 impB/mucB/samB family MCPsignal PF00015.21 CDS26760.1 - 0.082 12.7 7.4 1.3 8.8 0.7 2.6 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Isochorismatase PF00857.20 CDS26760.1 - 0.18 11.9 2.2 0.28 11.4 0.2 2.1 2 1 0 2 2 2 0 Isochorismatase family Arc_PepC_II PF06847.11 CDS26760.1 - 0.32 11.5 6.8 2.2 8.9 0.1 3.3 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Fez1 PF06818.15 CDS26760.1 - 0.67 10.4 15.3 3.7 8.0 1.1 2.2 2 0 0 2 2 2 0 Fez1 Mod_r PF07200.13 CDS26760.1 - 0.97 9.5 13.3 0.57 10.3 3.4 2.6 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DVL PF08137.12 CDS26760.1 - 1.5 8.8 4.4 3.4 7.6 4.4 1.6 1 0 0 1 1 1 0 DVL family DUF2203 PF09969.9 CDS26760.1 - 3.6 8.3 12.6 5.4 7.8 1.5 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF16 PF01519.16 CDS26760.1 - 3.7 8.1 12.9 0.32 11.5 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1910 PF08928.10 CDS26760.1 - 6.5 6.8 14.3 0.083 12.9 1.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1910) LOH1CR12 PF10158.9 CDS26760.1 - 8.9 6.3 11.7 3 7.9 2.4 3.0 2 1 1 3 3 3 0 Tumour suppressor protein UDPGP PF01704.18 CDS26761.1 - 6.1e-148 492.9 0.7 7.7e-148 492.5 0.7 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Bactofilin PF04519.13 CDS26761.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Polymer-forming cytoskeletal PHD PF00628.29 CDS26762.1 - 6.5e-07 29.1 8.4 1.1e-06 28.4 8.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDS26762.1 - 0.058 13.0 2.6 0.1 12.2 2.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 CDS26762.1 - 0.22 11.8 3.5 0.46 10.8 3.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Tektin PF03148.14 CDS26762.1 - 0.32 9.7 4.6 0.042 12.6 0.6 1.5 2 0 0 2 2 2 0 Tektin family zf-RING_2 PF13639.6 CDS26762.1 - 3.4 8.1 10.6 0.68 10.3 7.2 1.6 2 0 0 2 2 2 0 Ring finger domain zf-RING-like PF08746.11 CDS26762.1 - 7.9 6.9 8.8 0.78 10.1 4.3 1.7 2 0 0 2 2 2 0 RING-like domain RhoGEF PF00621.20 CDS26763.1 - 9.9e-38 130.2 6.2 2e-37 129.2 6.2 1.5 1 0 0 1 1 1 1 RhoGEF domain SH2 PF00017.24 CDS26763.1 - 4e-17 62.1 0.0 1.2e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 SH2 domain CH PF00307.31 CDS26763.1 - 9.3e-15 54.8 0.0 3.4e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SH3_1 PF00018.28 CDS26763.1 - 1.9e-13 49.8 0.2 4.4e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDS26763.1 - 4e-12 45.6 0.0 1.4e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 CDS26763.1 - 3.2e-10 39.7 0.1 2.9e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 CDS26763.1 - 5.6e-09 35.8 1.1 1.7e-08 34.2 1.1 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 CDS26763.1 - 9.5e-06 26.1 0.0 3.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 CDS26763.1 - 4e-05 23.4 0.2 9.8e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 CAMSAP CH domain PH_10 PF15411.6 CDS26763.1 - 0.00033 20.9 1.0 0.0056 16.9 0.0 2.7 2 1 1 3 3 3 1 Pleckstrin homology domain CDC24 PF06395.11 CDS26763.1 - 0.11 12.8 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 CDC24 Calponin Pkinase_Tyr PF07714.17 CDS26764.1 - 1.9e-82 276.5 0.0 2.8e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS26764.1 - 4.4e-40 137.7 0.0 7.1e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS26764.1 - 1.1e-19 70.3 0.0 1.9e-17 63.1 0.0 2.7 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.28 CDS26764.1 - 2.4e-12 46.2 0.0 4.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS26764.1 - 1.9e-11 43.6 0.1 1.5e-10 40.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CDS26764.1 - 1.2e-07 31.3 0.0 2.9e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BTK PF00779.19 CDS26764.1 - 4.1e-05 23.3 0.6 4.1e-05 23.3 0.6 2.1 2 0 0 2 2 2 1 BTK motif PH PF00169.29 CDS26764.1 - 6.6e-05 23.4 0.2 0.0026 18.3 0.1 2.4 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 CDS26764.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_10 PF17902.1 CDS26764.1 - 0.014 15.4 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 SH3 domain hSH3 PF14603.6 CDS26764.1 - 0.017 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain APH PF01636.23 CDS26764.1 - 0.046 13.6 0.4 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cm_res_leader PF08077.11 CDS26764.1 - 0.38 11.0 1.2 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide Sep15_SelM PF08806.11 CDS26765.1 - 1.2e-14 54.2 0.1 1.4e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain WD40 PF00400.32 CDS26766.1 - 1.3e-11 44.9 7.7 0.0051 17.6 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS26766.1 - 0.00017 21.8 0.0 0.23 11.8 0.0 3.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDS26766.1 - 0.0013 18.7 0.1 0.12 12.4 0.1 3.2 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 CDS26766.1 - 0.0043 16.9 0.1 0.62 9.9 0.1 3.1 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A polyprenyl_synt PF00348.17 CDS26767.1 - 1.1e-67 227.8 0.6 1.5e-67 227.4 0.6 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase KH_1 PF00013.29 CDS26769.1 - 0.0011 18.8 3.8 0.0023 17.7 3.8 1.5 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 CDS26769.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain PEN-2 PF10251.9 CDS26770.1 - 7.8e-35 119.2 1.8 8.4e-35 119.1 1.8 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF3810 PF12725.7 CDS26770.1 - 0.45 9.8 1.6 0.54 9.6 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) NPR3 PF03666.13 CDS26772.1 - 1.4e-16 60.4 0.3 3.6e-16 59.0 0.1 1.7 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF4703 PF15775.5 CDS26774.1 - 0.013 15.3 1.1 0.019 14.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Kelch_1 PF01344.25 CDS26775.2 - 1.3e-07 31.1 0.5 1.9e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CDS26775.2 - 1.7e-07 31.2 0.6 1.2e-05 25.4 0.0 2.9 3 1 1 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CDS26775.2 - 0.0038 17.1 1.4 4.6 7.4 0.1 3.3 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CDS26775.2 - 0.064 13.3 0.2 0.83 9.7 0.0 2.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS26775.2 - 0.076 13.0 0.6 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CDS26777.2 - 1.7e-21 75.5 0.0 3.7e-09 36.0 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDS26777.2 - 1.1e-16 60.4 0.2 1.5e-06 28.3 0.0 4.4 3 1 1 4 4 4 2 Kelch motif BTB PF00651.31 CDS26777.2 - 2.6e-12 46.9 0.0 4.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDS26777.2 - 1e-08 35.0 0.4 3.8e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain BACK PF07707.15 CDS26777.2 - 1.6e-08 34.5 0.1 2.2e-05 24.5 0.0 2.8 1 1 2 3 3 3 2 BTB And C-terminal Kelch Kelch_3 PF13415.6 CDS26777.2 - 9.2e-08 32.2 0.0 5.4e-05 23.4 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS26777.2 - 2.2e-07 30.5 0.0 0.0072 16.3 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDS26777.2 - 1.8e-06 27.8 0.1 0.062 13.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif MFS_1 PF07690.16 CDS26778.2 - 1.6e-24 86.5 22.5 5.2e-16 58.5 1.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 CDS26778.2 - 0.07 12.9 3.5 0.93 9.3 0.2 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Exo_endo_phos PF03372.23 CDS26779.1 - 5e-05 22.9 0.0 0.00023 20.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_3 PF12836.7 CDS26779.1 - 0.17 12.2 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif 7tm_1 PF00001.21 CDS26780.1 - 4e-39 134.5 11.2 4.8e-20 72.0 0.5 2.3 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDS26780.1 - 8.9e-07 28.9 1.4 8.9e-07 28.9 1.4 3.3 4 0 0 4 4 4 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 CDS26780.1 - 0.00045 19.7 2.2 0.00045 19.7 2.2 2.9 2 1 2 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srsx Orf78 PF06024.12 CDS26780.1 - 0.019 15.3 0.5 0.019 15.3 0.5 2.9 3 0 0 3 3 3 0 Orf78 (ac78) zf-LITAF-like PF10601.9 CDS26780.1 - 8.8 6.7 7.4 2 8.8 0.4 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Cyclin_N PF00134.23 CDS26781.1 - 8.7e-07 28.7 0.3 1.5e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain T-box PF00907.22 CDS26782.1 - 5.5e-77 258.2 0.0 7.9e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 T-box Cullin_binding PF03556.15 CDS26783.1 - 1.1e-30 106.5 1.1 2e-30 105.7 1.1 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CDS26783.1 - 1.8e-06 27.7 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Ras PF00071.22 CDS26784.1 - 1.9e-30 105.6 0.0 2.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS26784.1 - 3.2e-15 56.4 0.0 4.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDS26784.1 - 9.6e-05 22.4 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS26784.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDS26784.1 - 0.13 12.2 0.0 0.86 9.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase GTP1_OBG PF01018.22 CDS26785.1 - 1.9e-42 144.5 0.2 2.6e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 GTP1/OBG TMEM70 PF06979.12 CDS26785.1 - 4.1e-23 82.2 6.4 6.8e-23 81.5 6.4 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex MMR_HSR1 PF01926.23 CDS26785.1 - 1e-20 73.9 0.0 1.8e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS26785.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS26785.1 - 9.1e-05 22.6 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin family SF1-HH PF16275.5 CDS26786.1 - 1.4e-38 131.7 3.7 2.7e-38 130.8 3.7 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CDS26786.1 - 4.1e-09 36.1 0.6 9.5e-09 35.0 0.6 1.7 1 1 0 1 1 1 1 KH domain zf-CCHC PF00098.23 CDS26786.1 - 0.002 18.1 0.2 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CDS26786.1 - 0.0064 16.2 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CDS26786.1 - 0.036 13.9 0.2 0.12 12.2 0.2 2.0 1 0 0 1 1 1 0 Zinc knuckle FXR_C1 PF16096.5 CDS26786.1 - 0.068 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 UPF0181 PF03701.14 CDS26786.1 - 0.08 12.6 0.3 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) CCDC24 PF15669.5 CDS26787.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family fn3_4 PF16794.5 CDS26788.2 - 1.6e-23 82.5 0.0 3.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin-III type domain zf-C2H2_4 PF13894.6 CDS26788.2 - 3.3e-05 24.3 10.1 0.02 15.7 1.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS26788.2 - 0.0015 18.2 8.5 0.24 11.2 1.3 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 CDS26788.2 - 0.004 17.5 9.0 0.042 14.3 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS26788.2 - 0.11 13.0 5.2 5.9 7.5 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CDS26788.2 - 0.12 13.1 2.5 2.6 8.7 0.2 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 CDS26788.2 - 0.16 11.9 7.5 0.078 12.9 2.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Elf1 PF05129.13 CDS26788.2 - 0.31 11.1 5.0 0.73 9.9 5.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 CDS26788.2 - 2.7 8.2 5.4 11 6.3 0.8 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger zf-BED PF02892.15 CDS26788.2 - 6.2 6.9 14.0 0.29 11.2 1.0 2.8 2 1 1 3 3 3 0 BED zinc finger DUF382 PF04037.13 CDS26790.1 - 7e-58 194.3 0.9 7e-58 194.3 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 CDS26790.1 - 8.2e-19 67.2 4.0 2e-18 66.0 4.0 1.7 1 0 0 1 1 1 1 PSP ABC_tran PF00005.27 CDS26791.1 - 5.3e-41 140.3 0.0 5.6e-21 75.5 0.0 4.3 5 1 0 5 5 3 2 ABC transporter AAA_21 PF13304.6 CDS26791.1 - 2.3e-14 53.9 10.2 7.8e-05 22.6 0.1 4.8 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDS26791.1 - 1.7e-08 34.8 2.6 0.0033 17.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CDS26791.1 - 4.7e-06 26.6 0.0 0.013 15.4 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDS26791.1 - 4.9e-06 26.6 0.0 0.00081 19.5 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 CDS26791.1 - 6e-06 26.2 13.8 6e-06 26.2 13.8 4.2 4 1 0 4 4 2 1 ABC transporter AAA PF00004.29 CDS26791.1 - 7.4e-06 26.4 0.6 0.41 11.1 0.0 3.8 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS26791.1 - 1.4e-05 25.5 0.2 0.11 12.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CDS26791.1 - 2e-05 24.2 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 CDS26791.1 - 2.9e-05 24.3 1.3 0.39 10.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CDS26791.1 - 3.2e-05 23.8 0.0 0.14 11.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDS26791.1 - 0.00018 21.9 0.0 0.56 10.6 0.0 3.1 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 CDS26791.1 - 0.00032 20.6 0.1 0.47 10.3 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CDS26791.1 - 0.00056 20.2 0.0 1.2 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CDS26791.1 - 0.00089 19.3 0.1 2.9 7.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CDS26791.1 - 0.002 18.7 0.0 0.081 13.4 0.0 6.1 5 1 0 5 5 3 2 AAA domain AAA_7 PF12775.7 CDS26791.1 - 0.0026 17.3 0.0 2.1 7.8 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 CDS26791.1 - 0.0037 17.8 11.7 0.32 11.6 0.0 4.7 4 2 1 5 5 3 2 AAA domain AAA_5 PF07728.14 CDS26791.1 - 0.0041 17.1 0.1 3 7.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDS26791.1 - 0.0042 16.5 0.2 7.5 5.9 0.0 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CDS26791.1 - 0.0045 16.9 3.5 1.2 9.0 0.1 3.7 4 0 0 4 4 3 2 NTPase AAA_30 PF13604.6 CDS26791.1 - 0.0061 16.3 0.0 3.5 7.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CDS26791.1 - 0.014 15.0 1.9 11 5.5 0.0 3.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Roc PF08477.13 CDS26791.1 - 0.019 15.2 0.0 9 6.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CDS26791.1 - 0.036 14.1 0.1 7.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CDS26791.1 - 0.056 13.0 6.3 0.24 11.0 0.0 4.1 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CDS26791.1 - 0.21 11.6 0.0 0.21 11.6 0.0 4.9 5 1 1 6 6 5 0 Helicase HerA, central domain ATPase_2 PF01637.18 CDS26791.1 - 0.63 9.9 0.0 0.63 9.9 0.0 4.2 4 1 0 4 4 4 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 CDS26791.1 - 3.5 7.7 0.0 3.5 7.7 0.0 4.8 5 2 0 5 5 3 0 Dynamin family ATP_bind_1 PF03029.17 CDS26791.1 - 6.7 6.4 6.7 7.3 6.3 0.1 3.6 4 1 0 4 4 3 0 Conserved hypothetical ATP binding protein Band_7 PF01145.25 CDS26792.1 - 8.9e-28 97.5 0.7 1.3e-27 96.9 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDS26792.1 - 0.0071 16.1 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 SPFH domain-Band 7 family HTH_48 PF17906.1 CDS26793.1 - 9.2e-11 41.7 0.1 1.3e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Exo_endo_phos_2 PF14529.6 CDS26794.1 - 1.6e-13 50.5 0.3 3.2e-13 49.6 0.3 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26794.1 - 7.1e-05 22.4 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SLIDE PF09111.10 CDS26796.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 SLIDE PARP PF00644.20 CDS26797.1 - 5.5e-19 68.5 0.1 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain MMS22L_N PF14910.6 CDS26797.1 - 0.084 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Na_K-ATPase PF00287.18 CDS26798.1 - 2.1e-44 151.8 0.5 2.6e-44 151.5 0.5 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain SPT_ssu-like PF11779.8 CDS26798.1 - 0.11 12.1 3.9 0.087 12.5 1.8 1.9 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like Ribosomal_S8e PF01201.22 CDS26799.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e GhoS PF11080.8 CDS26799.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease GhoS Annexin PF00191.20 CDS26800.1 - 7.2e-70 231.0 16.7 4.2e-22 78.0 0.9 4.8 4 1 0 4 4 4 4 Annexin DUF3826 PF12875.7 CDS26800.1 - 0.044 13.9 1.8 0.33 11.1 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3826) Annexin PF00191.20 CDS26801.1 - 1e-76 252.9 10.5 3.4e-21 75.1 0.3 4.1 4 0 0 4 4 4 4 Annexin Myb_DNA-bind_7 PF15963.5 CDS26801.1 - 0.0062 16.4 0.9 3.3 7.7 0.0 2.8 3 0 0 3 3 3 2 Myb DNA-binding like Annexin PF00191.20 CDS26802.2 - 6.6e-78 256.8 7.4 1.4e-20 73.1 0.1 4.1 4 0 0 4 4 4 4 Annexin Ist1 PF03398.14 CDS26802.2 - 0.023 14.6 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Regulator of Vps4 activity in the MVB pathway Mito_fiss_reg PF05308.11 CDS26807.2 - 0.018 15.2 5.0 0.019 15.0 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CDS26807.2 - 0.047 13.2 6.9 0.054 13.0 6.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Annexin PF00191.20 CDS26811.1 - 1e-44 150.4 2.7 4.4e-12 45.9 0.0 4.2 4 0 0 4 4 4 4 Annexin Nitr_red_assoc PF09655.10 CDS26812.2 - 0.67 10.6 3.6 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Aldedh PF00171.22 CDS26815.1 - 8.5e-148 492.7 0.1 9.7e-148 492.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CDS26815.1 - 0.013 15.0 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) 7tm_1 PF00001.21 CDS26816.1 - 1.9e-39 135.6 12.6 2.6e-39 135.1 12.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS26816.1 - 4.3e-10 39.4 14.7 2.3e-08 33.8 10.2 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS26816.1 - 0.00025 20.8 10.9 0.0012 18.5 10.9 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Homeodomain PF00046.29 CDS26819.1 - 3.3e-12 46.0 3.9 7.5e-12 44.9 3.9 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS26819.1 - 0.044 13.7 0.2 0.18 11.8 0.2 2.2 1 1 0 1 1 1 0 Homeobox KN domain CCT_2 PF09425.10 CDS26819.1 - 0.21 11.5 1.8 0.52 10.2 1.8 1.7 1 0 0 1 1 1 0 Divergent CCT motif FKBP_C PF00254.28 CDS26820.1 - 2.3e-38 130.4 0.0 2.6e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IgGFc_binding PF17517.2 CDS26820.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 IgGFc binding protein Fcf1 PF04900.12 CDS26821.2 - 0.0099 16.3 0.0 0.68 10.4 0.0 2.5 2 0 0 2 2 2 2 Fcf1 UQ_con PF00179.26 CDS26822.1 - 3.2e-46 156.5 0.0 3.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDS26822.1 - 0.0038 17.1 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 CDS26823.1 - 6.9e-46 155.4 0.0 7.8e-46 155.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS26823.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDS26823.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF525 PF04379.14 CDS26824.1 - 1.2e-20 73.5 0.2 2.3e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 ApaG domain Radial_spoke PF04712.12 CDS26828.1 - 1.4e-102 344.2 2.8 1.4e-102 344.2 2.8 1.6 1 1 1 2 2 2 1 Radial spokehead-like protein La PF05383.17 CDS26830.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 La domain La PF05383.17 CDS26831.1 - 0.02 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 La domain La PF05383.17 CDS26832.1 - 0.041 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 La domain La PF05383.17 CDS26833.1 - 0.004 17.2 0.3 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 La domain Endopep_inhib PF16800.5 CDS26833.1 - 0.078 12.9 0.4 0.3 11.0 0.5 1.8 1 1 0 1 1 1 0 IseA DL-endopeptidase inhibitor La PF05383.17 CDS26834.1 - 0.015 15.3 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 La domain Ank_4 PF13637.6 CDS26837.2 - 4.7e-25 87.6 1.7 3.3e-07 30.7 0.0 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS26837.2 - 1.6e-24 85.6 5.5 4.1e-08 33.3 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) PRKG1_interact PF15898.5 CDS26837.2 - 1.8e-23 83.3 7.2 1.8e-23 83.3 7.2 3.6 3 0 0 3 3 3 1 cGMP-dependent protein kinase interacting domain Ank_2 PF12796.7 CDS26837.2 - 3.2e-22 78.9 2.2 2e-10 41.1 0.9 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS26837.2 - 1.1e-14 53.1 4.4 0.0067 16.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CDS26837.2 - 9.6e-14 51.1 14.4 0.00012 22.4 0.1 5.8 5 1 0 5 5 5 3 Ankyrin repeat DUF2205 PF10224.9 CDS26837.2 - 0.15 12.0 3.4 13 5.9 0.6 2.8 2 0 0 2 2 2 0 Short coiled-coil protein BSD PF03909.17 CDS26838.1 - 1e-13 51.1 0.7 3.6e-13 49.3 0.1 2.3 2 0 0 2 2 2 1 BSD domain Ribosomal_L7Ae PF01248.26 CDS26839.1 - 2e-14 53.1 0.4 2.7e-14 52.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SHR-BD PF06650.12 CDS26840.1 - 2.6e-35 122.1 0.0 7.6e-34 117.3 0.0 3.2 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 CDS26840.1 - 1.8e-26 93.4 0.2 2.8e-25 89.5 0.0 2.9 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDS26840.1 - 1.1e-24 86.8 0.4 3e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CDS26840.1 - 8.3e-23 81.1 0.7 4.2e-16 59.2 0.0 3.6 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 CDS26840.1 - 7.4e-06 25.6 0.0 0.022 14.2 0.0 4.3 4 0 0 4 4 4 1 Repeating coiled region of VPS13 UBA PF00627.31 CDS26840.1 - 0.01 15.8 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF848 PF05852.11 CDS26840.1 - 0.087 12.9 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FYVE_2 PF02318.16 CDS26841.1 - 2.3e-18 66.5 6.9 2.3e-18 66.5 6.9 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger PcfK PF14058.6 CDS26841.1 - 0.00068 19.9 0.3 0.0038 17.5 0.1 2.1 1 1 1 2 2 2 1 PcfK-like protein C1_1 PF00130.22 CDS26841.1 - 0.062 13.2 10.0 0.046 13.6 5.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RICH PF05062.12 CDS26841.1 - 0.077 13.3 1.3 0.25 11.7 1.3 1.8 1 0 0 1 1 1 0 RICH domain PARG_cat PF05028.14 CDS26841.1 - 0.1 11.8 2.5 0.12 11.6 1.3 1.7 1 1 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) FYVE PF01363.21 CDS26841.1 - 0.11 12.7 12.6 0.4 10.8 12.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 CDS26841.1 - 0.18 12.1 8.8 0.76 10.0 8.3 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain RRF PF01765.19 CDS26841.1 - 0.96 9.4 8.8 1.9 8.4 2.5 2.5 2 0 0 2 2 2 0 Ribosome recycling factor RRM_1 PF00076.22 CDS26842.1 - 1.1e-12 47.6 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS26842.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF2096 PF09869.9 CDS26843.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Jnk-SapK_ap_N PF09744.9 CDS26844.1 - 4.7e-44 150.4 15.0 4.7e-44 150.4 15.0 2.5 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 CDS26844.1 - 4.9e-15 55.5 11.6 4.9e-15 55.5 11.6 4.6 3 2 2 5 5 5 1 JNK-interacting protein leucine zipper II Spc7 PF08317.11 CDS26844.1 - 0.0075 15.2 26.1 0.019 13.9 7.5 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein zf-C4H2 PF10146.9 CDS26844.1 - 0.013 15.8 16.7 0.22 11.8 11.1 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 CDS26844.1 - 0.033 13.7 24.1 0.33 10.4 11.3 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HALZ PF02183.18 CDS26844.1 - 0.4 11.0 19.7 0.87 9.9 5.4 4.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper ADIP PF11559.8 CDS26844.1 - 1.3 9.0 27.4 0.61 10.2 5.5 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 CDS26844.1 - 3.9 7.7 18.5 0.2 11.9 8.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KASH_CCD PF14662.6 CDS26844.1 - 7.3 6.4 31.5 9.9 5.9 13.4 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATP-synt_C PF00137.21 CDS26845.1 - 4.2e-25 87.9 37.7 4.2e-14 52.6 12.2 2.6 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 CDS26845.1 - 0.19 11.0 0.4 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PIRT PF15099.6 CDS26845.1 - 7.4 6.2 8.6 0.7 9.5 0.1 2.5 3 1 0 3 3 3 0 Phosphoinositide-interacting protein family SET PF00856.28 CDS26846.1 - 4.5e-17 63.0 0.1 1.1e-15 58.5 0.1 2.3 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CDS26846.1 - 1.4e-08 35.4 6.5 1.4e-08 35.4 6.5 2.2 2 1 0 2 2 2 1 Pre-SET motif Nodulin-like PF06813.13 CDS26847.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Nodulin-like Endotoxin_M PF00555.19 CDS26847.1 - 0.063 13.3 1.1 0.72 9.9 0.2 2.2 2 0 0 2 2 2 0 delta endotoxin MFS_1 PF07690.16 CDS26848.1 - 2.6e-14 52.9 29.3 2.6e-14 52.9 29.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2672 PF10878.8 CDS26848.1 - 0.049 13.6 0.8 0.6 10.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) RSB_motif PF16294.5 CDS26850.1 - 9.5e-16 57.9 3.1 9.5e-16 57.9 3.1 3.0 1 1 1 2 2 2 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 CDS26850.1 - 2.7e-09 36.6 3.0 5.4e-09 35.6 3.0 1.6 1 0 0 1 1 1 1 SAP domain RRM_1 PF00076.22 CDS26850.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 CDS26852.1 - 6.6e-50 168.9 0.0 7.7e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS26852.1 - 1.3e-25 90.0 0.0 1.7e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS26852.1 - 3.2e-11 43.0 0.0 4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS26852.1 - 8e-05 22.7 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDS26852.1 - 0.00053 19.4 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDS26852.1 - 0.0084 16.0 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDS26852.1 - 0.015 14.8 0.0 0.079 12.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDS26852.1 - 0.024 14.2 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Amidase02_C PF12123.8 CDS26852.1 - 0.079 12.7 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Sec23_trunk PF04811.15 CDS26853.1 - 1.2e-53 182.2 0.0 1.7e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDS26853.1 - 6.6e-20 70.9 0.2 1.3e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CDS26853.1 - 4.8e-15 56.1 0.0 1.1e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDS26853.1 - 1.3e-13 50.8 1.7 3.1e-13 49.5 1.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDS26853.1 - 9e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat ARL6IP6 PF15062.6 CDS26853.1 - 0.044 13.9 0.9 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix UPF0193 PF05250.11 CDS26854.1 - 7.3e-33 114.2 0.7 8.6e-33 114.0 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) AAA_23 PF13476.6 CDS26854.1 - 0.0093 16.5 2.3 0.011 16.3 2.3 1.1 1 0 0 1 1 1 1 AAA domain TspO_MBR PF03073.15 CDS26855.1 - 2.8e-41 140.7 8.2 3.2e-41 140.5 8.2 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF4534 PF15049.6 CDS26855.1 - 0.043 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) PH PF00169.29 CDS26856.1 - 1.1e-08 35.5 0.0 0.00043 20.8 0.0 2.6 2 0 0 2 2 2 2 PH domain RRM_1 PF00076.22 CDS26857.2 - 9.4e-06 25.4 0.1 0.29 11.0 0.1 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4695 PF15766.5 CDS26858.1 - 2.4e-07 31.0 0.4 2.9e-07 30.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4695) RSF PF14876.6 CDS26861.1 - 0.055 12.4 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator PDZ PF00595.24 CDS26863.1 - 2.3e-09 37.5 0.1 6.4e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Exo_endo_phos_2 PF14529.6 CDS26864.1 - 9.5e-08 31.9 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26864.1 - 0.0096 15.5 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Med11 PF10280.9 CDS26866.1 - 2.8e-09 37.6 0.1 4.3e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Mediator complex protein Na_sulph_symp PF00939.19 CDS26867.2 - 3.4e-72 244.0 14.6 4.5e-72 243.6 14.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDS26867.2 - 4.4e-31 108.2 29.5 3.4e-15 56.0 5.8 3.5 2 1 1 3 3 3 3 Citrate transporter DctM PF06808.12 CDS26867.2 - 0.00013 20.9 10.2 0.00013 20.9 10.2 2.3 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporter, DctM component GntP_permease PF02447.16 CDS26867.2 - 2.9 6.5 18.7 0.029 13.1 6.7 2.7 2 1 1 3 3 3 0 GntP family permease CUB PF00431.20 CDS26868.2 - 2.6e-58 195.1 0.9 1.3e-16 60.9 0.1 6.8 6 1 0 7 7 7 5 CUB domain Ldl_recept_a PF00057.18 CDS26868.2 - 0.0081 16.3 6.0 0.043 14.0 6.0 2.2 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A DnaJ_C PF01556.18 CDS26869.1 - 1.2e-32 113.1 0.0 1.7e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDS26869.1 - 8.3e-18 64.3 0.4 1.6e-17 63.4 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4139 PF13598.6 CDS26870.1 - 5.6e-40 137.3 0.1 1.3e-39 136.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CDS26870.1 - 3.8e-21 75.3 4.7 1.2e-19 70.5 0.3 3.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Top6b_C PF18000.1 CDS26870.1 - 0.0037 17.4 0.4 0.0083 16.3 0.4 1.6 1 0 0 1 1 1 1 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF4201 PF13870.6 CDS26870.1 - 0.074 12.8 6.7 0.78 9.5 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 CDS26870.1 - 1.2 9.3 6.5 19 5.4 0.1 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 CDS26870.1 - 2.4 7.4 5.9 5.8 6.2 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CDS26870.1 - 2.7 8.7 9.8 4 8.1 0.3 3.5 2 0 0 2 2 2 0 SlyX DUF4349 PF14257.6 CDS26870.1 - 6 6.2 8.9 4 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) SBF2 PF12335.8 CDS26871.1 - 9.5e-07 28.7 1.7 9.4e-06 25.4 0.0 2.6 2 0 0 2 2 2 1 Myotubularin protein YabA PF06156.13 CDS26871.1 - 0.36 11.5 6.7 0.57 10.9 0.0 3.6 3 0 0 3 3 3 0 Initiation control protein YabA Pkinase PF00069.25 CDS26872.1 - 2e-27 96.2 0.0 8.6e-27 94.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26872.1 - 4.2e-16 59.0 0.0 1.4e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26872.1 - 0.0034 16.2 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CDS26872.1 - 0.035 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CDS26873.1 - 3.6e-53 180.6 0.0 4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26873.1 - 2.1e-27 96.1 0.0 2.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS26873.1 - 8.1e-06 25.3 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 CDS26873.1 - 0.018 14.7 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDS26873.1 - 0.025 13.3 0.0 0.063 12.0 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CDS26873.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDS26873.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CDS26873.1 - 0.087 11.8 0.7 0.16 10.9 0.4 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_S26e PF01283.19 CDS26874.1 - 5.1e-50 168.4 9.0 5.5e-50 168.3 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e CxxCxxCC PF03692.15 CDS26874.1 - 0.017 15.8 1.8 0.022 15.5 1.8 1.3 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain RRM_1 PF00076.22 CDS26875.1 - 5.7e-43 144.6 0.1 4.2e-21 74.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS26875.1 - 1.4e-08 34.4 0.0 1.1e-06 28.2 0.1 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDS26875.1 - 7e-05 22.8 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 CDS26875.1 - 0.00049 19.9 0.0 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Pkinase PF00069.25 CDS26876.1 - 1.2e-32 113.3 0.0 1.9e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26876.1 - 1.2e-29 103.4 0.0 1.4e-20 73.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26876.1 - 0.00017 20.5 0.0 0.0064 15.3 0.1 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CDS26876.1 - 0.021 14.7 0.5 0.9 9.4 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CDS26876.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.28 CDS26877.1 - 1.1e-15 57.8 0.2 2.1e-15 56.9 0.2 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CDS26877.1 - 5.1e-11 42.7 0.0 1.3e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDS26877.1 - 0.00037 20.3 0.3 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 LisH Pkinase PF00069.25 CDS26878.1 - 1.9e-49 168.4 0.0 2.3e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26878.1 - 2.3e-20 73.0 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS26878.1 - 4.1e-05 23.6 0.3 5.7e-05 23.2 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS26878.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CDS26878.1 - 0.014 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDS26880.1 - 2.9e-70 236.7 0.0 4e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26880.1 - 1.5e-32 112.9 0.0 2.6e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS26880.1 - 9e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS26880.1 - 0.00018 20.6 0.4 0.00056 18.9 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS26880.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ECSIT PF06239.11 CDS26881.1 - 1.6e-50 171.3 0.0 2.4e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway zf-CDGSH PF09360.10 CDS26881.1 - 1.1e-14 54.3 4.0 5.3e-08 33.0 0.6 2.5 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type ECSIT_C PF14784.6 CDS26881.1 - 2.1e-07 31.4 0.2 0.008 16.5 0.0 3.5 3 0 0 3 3 3 2 C-terminal domain of the ECSIT protein Ist1 PF03398.14 CDS26882.1 - 3e-58 196.4 3.8 3.7e-58 196.1 3.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ldh_1_N PF00056.23 CDS26883.1 - 2.8e-44 150.6 1.5 3.9e-44 150.2 1.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDS26883.1 - 2e-22 79.9 0.0 5.2e-22 78.6 0.0 1.7 2 1 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.21 CDS26883.1 - 0.00047 19.6 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_Gly3P_dh_N PF01210.23 CDS26883.1 - 0.0054 16.7 0.1 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 CDS26883.1 - 0.0063 16.8 0.5 0.014 15.6 0.5 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CDS26883.1 - 0.0079 15.6 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CDS26883.1 - 0.011 15.3 0.7 0.089 12.3 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase 3HCDH_N PF02737.18 CDS26883.1 - 0.012 15.5 0.4 0.012 15.5 0.4 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CDS26883.1 - 0.049 12.9 0.3 0.071 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.12 CDS26883.1 - 0.054 13.1 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 CDS26883.1 - 0.061 12.9 2.5 0.09 12.3 1.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 CDS26883.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CDS26883.1 - 0.11 12.5 0.9 0.29 11.2 0.5 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 CDS26883.1 - 0.2 11.2 4.5 0.62 9.6 4.5 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CDS26883.1 - 0.26 11.8 1.5 0.73 10.3 1.4 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Macoilin PF09726.9 CDS26884.1 - 1.3e-42 146.3 8.7 1.5e-42 146.1 8.7 1.0 1 0 0 1 1 1 1 Macoilin family Bunya_G2 PF03563.13 CDS26884.1 - 0.099 11.9 0.3 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 BTB_2 PF02214.22 CDS26887.1 - 5.1e-16 58.8 0.0 3.3e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DENN PF02141.21 CDS26889.1 - 3.8e-33 115.0 1.2 1e-32 113.6 1.2 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CDS26889.1 - 4.5e-18 65.7 1.0 1.6e-17 64.0 0.5 2.4 2 0 0 2 2 2 1 uDENN domain Ehrlichia_rpt PF09528.10 CDS26889.1 - 0.021 14.3 0.8 0.055 12.9 0.8 1.6 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) SBF2 PF12335.8 CDS26889.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Myotubularin protein MIR PF02815.19 CDS26890.1 - 3.6e-11 43.2 0.6 2.1e-09 37.5 0.2 2.1 1 1 1 2 2 2 2 MIR domain Ras PF00071.22 CDS26891.1 - 3.8e-62 208.7 2.4 4.4e-62 208.5 2.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS26891.1 - 3e-35 121.0 0.8 4.4e-35 120.5 0.8 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS26891.1 - 5.7e-16 58.5 0.4 6.6e-16 58.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS26891.1 - 1.7e-06 27.6 1.9 3.2e-06 26.7 1.9 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDS26891.1 - 1.8e-05 24.3 0.9 3.4e-05 23.5 0.5 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS26891.1 - 7.9e-05 22.6 1.2 0.091 12.7 0.3 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDS26891.1 - 0.00022 21.3 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDS26891.1 - 0.0019 18.0 0.4 0.0049 16.7 0.1 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 CDS26891.1 - 0.004 16.6 0.2 0.0056 16.1 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 CDS26891.1 - 0.011 15.1 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CDS26891.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF3963 PF13124.6 CDS26891.1 - 0.014 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) PduV-EutP PF10662.9 CDS26891.1 - 0.016 14.9 0.8 0.1 12.4 0.8 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CDS26891.1 - 0.022 14.3 0.2 0.15 11.6 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 CDS26891.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TOPRIM_C PF16898.5 CDS26891.1 - 0.054 13.8 0.1 0.097 12.9 0.1 1.5 1 1 0 1 1 1 0 C-terminal associated domain of TOPRIM AAA PF00004.29 CDS26891.1 - 0.1 13.1 0.2 0.58 10.6 0.1 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDS26891.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein SHE3 PF17078.5 CDS26893.1 - 0.18 11.5 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF724 PF05266.14 CDS26894.1 - 0.033 14.0 1.9 0.091 12.6 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FIVAR PF07554.13 CDS26894.1 - 0.051 14.3 3.0 0.31 11.8 3.0 2.4 1 0 0 1 1 1 0 FIVAR domain WD-3 PF09765.9 CDS26894.1 - 0.053 12.8 0.4 4.4 6.6 0.5 2.7 3 0 0 3 3 3 0 WD-repeat region SLATT_5 PF18160.1 CDS26894.1 - 0.065 12.6 2.8 0.14 11.5 2.8 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Com_YlbF PF06133.11 CDS26894.1 - 0.75 10.4 6.4 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF4140 PF13600.6 CDS26894.1 - 2.5 8.6 6.6 41 4.7 2.6 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 CDS26894.1 - 7.4 6.8 9.7 4.4 7.5 3.3 3.7 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family COPIIcoated_ERV PF07970.12 CDS26895.1 - 2.7e-38 132.0 0.0 6.1e-38 130.9 0.0 1.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDS26895.1 - 3.7e-21 75.3 0.1 7.9e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Activator_LAG-3 PF11498.8 CDS26895.1 - 0.036 13.1 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4368 PF14287.6 CDS26895.1 - 0.14 12.5 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) bZIP_1 PF00170.21 CDS26896.1 - 7.7e-09 35.5 12.9 1.5e-08 34.6 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDS26896.1 - 2.7e-07 30.6 14.9 4.6e-07 29.8 14.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS26896.1 - 0.00021 21.7 16.2 0.00058 20.3 16.2 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor Peptidase_S64 PF08192.11 CDS26896.1 - 0.0014 17.2 1.1 0.0021 16.7 1.1 1.1 1 0 0 1 1 1 1 Peptidase family S64 Phlebovirus_NSM PF07246.11 CDS26896.1 - 0.21 10.9 2.3 0.34 10.2 2.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 CDS26896.1 - 1.2 8.4 3.3 1.8 7.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 CDS26896.1 - 1.4 7.4 7.5 2.3 6.7 7.5 1.3 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 CDS26896.1 - 4.8 7.0 5.7 0.74 9.6 1.3 1.8 1 1 1 2 2 2 0 Septum formation initiator Peptidase_M13_N PF05649.13 CDS26897.1 - 1.3e-76 258.8 1.0 1.8e-76 258.3 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDS26897.1 - 1e-70 237.5 0.0 3.7e-70 235.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 DUF4133 PF13571.6 CDS26897.1 - 0.29 11.5 0.8 0.6 10.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Baculo_11_kDa PF06143.11 CDS26897.1 - 0.54 9.9 2.8 1.3 8.6 2.8 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Arf PF00025.21 CDS26898.1 - 9e-75 249.9 0.0 1.1e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS26898.1 - 1.1e-13 51.5 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDS26898.1 - 2.2e-13 50.0 0.0 2.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDS26898.1 - 3.3e-12 46.3 0.3 4.9e-08 32.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDS26898.1 - 2.4e-11 43.5 0.0 2.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDS26898.1 - 3.3e-11 43.0 0.0 4.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS26898.1 - 5.6e-05 23.2 0.0 8.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDS26898.1 - 0.022 14.1 0.1 0.037 13.3 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Synapsin_C PF02750.14 CDS26899.1 - 1e-45 155.8 0.0 1.9e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 Synapsin, ATP binding domain Synapsin PF02078.16 CDS26899.1 - 7.6e-32 109.6 0.0 2e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Synapsin, N-terminal domain RRM_1 PF00076.22 CDS26901.1 - 1.1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CFAP91 PF14738.6 CDS26903.1 - 3.3e-43 147.4 7.4 3.3e-43 147.4 7.4 3.6 3 1 1 4 4 4 1 Cilia- and flagella-associated protein 91 Peptidase_M24_C PF16188.5 CDS26903.1 - 0.085 12.9 0.3 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Tfb5 PF06331.12 CDS26903.1 - 3 7.9 5.0 2.7 8.0 0.2 3.1 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 TNFR_c6 PF00020.18 CDS26904.1 - 0.0027 18.1 0.5 0.98 9.9 0.0 2.8 1 1 1 2 2 2 2 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 CDS26904.1 - 0.013 15.5 2.0 0.044 13.8 2.0 2.0 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR MipZ PF09140.11 CDS26904.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ Ephrin_rec_like PF07699.13 CDS26904.1 - 0.74 9.6 13.0 0.032 14.0 4.9 2.6 2 1 0 2 2 2 0 Putative ephrin-receptor like tRNA-synt_1d PF00750.19 CDS26905.1 - 6e-56 189.9 0.0 9.3e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDS26905.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 DALR anticodon binding domain LRR_4 PF12799.7 CDS26906.1 - 0.0076 16.7 0.1 2.4 8.7 0.1 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) JAB PF01398.21 CDS26907.1 - 2.2e-32 111.5 0.0 3.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDS26907.1 - 2.2e-14 53.8 0.6 3.8e-14 53.1 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CDS26907.1 - 6.6e-06 25.9 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SNF2_N PF00176.23 CDS26908.1 - 4.8e-25 88.0 0.0 8.2e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 CDS26908.1 - 1.4e-19 69.4 0.0 4.5e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 HepA-related protein (HARP) Helicase_C PF00271.31 CDS26908.1 - 2.6e-14 53.5 0.0 5.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS26908.1 - 1.3e-07 31.8 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDS26908.1 - 0.0035 17.1 0.1 0.019 14.7 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CDS26908.1 - 0.037 13.6 0.4 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 Pkinase PF00069.25 CDS26910.1 - 3.2e-67 226.7 0.0 4e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26910.1 - 7.5e-42 143.4 0.0 9.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS26910.1 - 1.1e-06 27.7 0.0 1.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDS26910.1 - 1.2e-06 28.1 0.0 2.3e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like DSHCT PF08148.12 CDS26910.1 - 0.0097 15.6 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.23 CDS26910.1 - 0.037 13.9 0.1 3.1 7.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS26910.1 - 0.066 12.1 0.4 0.089 11.7 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_S3_C PF00189.20 CDS26911.1 - 4.5e-23 81.6 0.1 5.3e-22 78.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CDS26911.1 - 2.7e-08 33.5 0.1 4.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 KH domain PHD PF00628.29 CDS26912.1 - 1.5e-16 60.0 27.4 5e-10 39.1 8.3 2.4 1 1 1 2 2 2 2 PHD-finger SAM_1 PF00536.30 CDS26912.1 - 1.1e-06 28.9 0.1 1.9e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS26912.1 - 4.1e-06 26.8 0.1 7.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CDS26912.1 - 0.004 17.1 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PHD_2 PF13831.6 CDS26912.1 - 0.0068 15.9 0.6 0.0068 15.9 0.6 3.2 3 1 0 3 3 3 2 PHD-finger C1_1 PF00130.22 CDS26912.1 - 0.17 11.8 27.3 0.033 14.1 5.2 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CDS26912.1 - 2.1 8.3 21.1 2.6 8.0 5.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ABC2_membrane PF01061.24 CDS26913.1 - 3.3e-29 101.8 18.4 3.3e-29 101.8 18.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDS26913.1 - 1.7e-21 77.2 0.0 3.9e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDS26913.1 - 1e-09 38.7 0.0 0.00091 19.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDS26913.1 - 4.8e-06 26.2 0.0 4.9e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDS26913.1 - 8.3e-06 26.4 0.8 1.6e-05 25.5 0.8 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDS26913.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 CDS26913.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CDS26913.1 - 0.076 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CDS26913.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 CDS26913.1 - 0.083 12.6 0.1 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CDS26913.1 - 0.12 12.8 0.1 0.58 10.6 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDS26913.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS26913.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS26913.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CDS26913.1 - 0.25 10.9 0.0 0.61 9.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SDF PF00375.18 CDS26914.1 - 1.2e-68 231.9 30.6 1.4e-68 231.7 30.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 CDS26915.1 - 1.8e-73 247.8 28.8 2.1e-73 247.6 28.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MscS_TM PF12794.7 CDS26915.1 - 0.011 14.6 3.8 0.1 11.4 0.9 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 SDF PF00375.18 CDS26916.1 - 2.8e-73 247.2 29.4 3.2e-73 247.0 29.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FAR1 PF03101.15 CDS26917.1 - 7.2e-08 33.0 0.5 7.3e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 FAR1 DNA-binding domain FLYWCH PF04500.16 CDS26917.1 - 0.00053 20.0 3.0 0.096 12.8 0.5 2.8 2 0 0 2 2 2 2 FLYWCH zinc finger domain MMTV_SAg PF01054.17 CDS26919.1 - 0.081 12.5 0.3 0.77 9.3 0.1 2.1 1 1 1 2 2 2 0 Mouse mammary tumour virus superantigen DALR_1 PF05746.15 CDS26920.1 - 0.038 14.2 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 DALR anticodon binding domain DUF4795 PF16043.5 CDS26920.1 - 0.066 12.8 0.3 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Rft-1 PF04506.13 CDS26922.1 - 3.1e-110 369.4 19.1 4.4e-110 368.8 19.1 1.2 1 0 0 1 1 1 1 Rft protein AAA PF00004.29 CDS26922.1 - 1.1e-39 135.9 0.0 2.4e-35 121.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS26922.1 - 2.3e-07 31.4 0.1 0.041 14.3 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain Rad17 PF03215.15 CDS26922.1 - 3.1e-07 30.5 1.1 0.0016 18.4 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_5 PF07728.14 CDS26922.1 - 4.7e-07 29.9 0.0 0.0007 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS26922.1 - 8.3e-05 22.9 0.0 0.16 12.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CDS26922.1 - 0.00017 21.7 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CDS26922.1 - 0.0015 18.9 0.0 2.5 8.5 0.0 2.9 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.12 CDS26922.1 - 0.031 14.0 0.0 0.095 12.4 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CDS26922.1 - 0.033 14.2 0.0 0.69 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CDS26922.1 - 0.05 13.3 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_lid_3 PF17862.1 CDS26922.1 - 0.057 13.2 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA+ lid domain NACHT PF05729.12 CDS26922.1 - 0.069 13.1 0.0 20 5.1 0.0 3.1 2 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 CDS26922.1 - 0.086 13.4 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CDS26922.1 - 0.099 11.8 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_2 PF07724.14 CDS26922.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ig_3 PF13927.6 CDS26923.1 - 6.6e-32 109.9 0.0 1.4e-07 32.0 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 CDS26923.1 - 2.1e-23 82.2 0.0 4.3e-06 26.7 0.0 5.6 6 1 0 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS26923.1 - 3.1e-23 81.9 0.3 0.00011 22.5 0.1 6.1 5 2 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 CDS26923.1 - 1.8e-17 63.2 0.0 0.00022 21.4 0.0 5.9 5 2 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 CDS26923.1 - 4e-11 43.0 0.2 6.7e-06 26.3 0.1 5.8 5 1 0 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS26923.1 - 2.2e-10 40.5 2.2 4.3e-08 33.1 0.0 4.4 4 2 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS26923.1 - 0.0014 18.2 0.1 2 8.1 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain DAP10 PF07213.11 CDS26923.1 - 0.037 14.0 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein UPF0560 PF10577.9 CDS26923.1 - 0.094 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Metallophos PF00149.28 CDS26925.1 - 1.6e-19 71.3 2.0 2.3e-19 70.7 1.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 CDS26925.1 - 2.4e-15 57.1 0.0 5.8e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 CDS26925.1 - 4.3e-15 56.1 2.7 1.1e-14 54.8 2.7 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 CDS26925.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Fibronectin type III domain SH3_1 PF00018.28 CDS26926.1 - 0.0016 18.0 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS26926.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDS26926.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DASH_Duo1 PF08651.10 CDS26927.1 - 0.15 11.9 4.1 5.7 6.8 0.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 CENP-Q PF13094.6 CDS26927.1 - 1.8 8.7 6.2 1.8 8.8 5.2 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1741 PF08427.10 CDS26928.1 - 8.5e-56 189.2 0.7 1.5e-55 188.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Rad60-SLD PF11976.8 CDS26929.1 - 2.2e-20 72.3 0.0 2.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDS26929.1 - 1.1e-08 34.7 0.0 1.2e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family ThiS PF02597.20 CDS26929.1 - 0.072 13.7 0.0 0.084 13.5 0.0 1.3 1 0 0 1 1 1 0 ThiS family RVT_1 PF00078.27 CDS26930.1 - 4.7e-11 42.6 0.0 8.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Annexin PF00191.20 CDS26932.2 - 2.2e-90 296.7 11.8 8e-25 86.7 0.3 4.3 4 0 0 4 4 4 4 Annexin Fn3_assoc PF13287.6 CDS26932.2 - 4.3e-09 36.4 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.6 CDS26932.2 - 1.3e-08 34.7 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Myb_DNA-bind_7 PF15963.5 CDS26932.2 - 0.021 14.7 1.3 0.4 10.6 0.1 3.4 4 0 0 4 4 4 0 Myb DNA-binding like Sec23_helical PF04815.15 CDS26932.2 - 0.17 11.8 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Sigma70_ner PF04546.13 CDS26932.2 - 8.6 6.2 9.2 3.2 7.6 2.5 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region SET PF00856.28 CDS26933.1 - 1.5e-24 87.2 0.0 6.5e-23 81.9 0.0 2.6 1 1 0 1 1 1 1 SET domain TUDOR_5 PF18359.1 CDS26933.1 - 1.5e-21 75.8 1.2 3.4e-21 74.7 1.2 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_4 PF18358.1 CDS26933.1 - 1.8e-21 75.5 0.1 4.9e-21 74.1 0.1 1.8 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Pre-SET PF05033.16 CDS26933.1 - 6.8e-19 68.5 10.8 1.9e-18 67.1 10.8 1.8 1 0 0 1 1 1 1 Pre-SET motif MBD PF01429.19 CDS26933.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain Ank_2 PF12796.7 CDS26934.2 - 7e-16 58.6 4.7 1.9e-12 47.6 0.8 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS26934.2 - 5e-12 45.8 3.5 3.9e-07 30.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS26934.2 - 5.8e-12 44.7 0.8 8.4e-05 22.7 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDS26934.2 - 8.2e-12 45.0 1.6 5.4e-05 23.4 0.9 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDS26934.2 - 8.5e-11 42.2 0.1 1.4e-05 25.6 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Cep57_CLD PF14073.6 CDS26934.2 - 0.0023 18.0 1.8 0.0023 18.0 1.8 1.7 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 SH3_9 PF14604.6 CDS26934.2 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS26934.2 - 0.053 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 SH3 domain TMF_DNA_bd PF12329.8 CDS26934.2 - 2.1 8.4 8.7 2 8.5 5.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_2 PF07719.17 CDS26935.1 - 3e-24 83.1 16.7 8.5e-05 22.4 0.3 10.4 11 1 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDS26935.1 - 3e-23 80.6 9.5 3.3e-05 23.5 0.8 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDS26935.1 - 8.9e-23 78.6 4.6 0.0018 18.3 0.2 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS26935.1 - 9.6e-20 70.6 19.6 5.6e-14 52.1 3.5 5.2 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDS26935.1 - 1.3e-18 66.4 0.0 0.00037 20.1 0.0 5.7 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.6 CDS26935.1 - 3e-16 59.7 7.4 0.00029 21.3 0.0 7.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS26935.1 - 8.8e-11 41.4 7.4 0.0014 18.9 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS26935.1 - 1.2e-10 41.3 12.0 2.2 9.3 0.0 9.1 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDS26935.1 - 6.8e-10 39.1 12.1 0.0016 18.7 0.0 6.4 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS26935.1 - 9.3e-09 35.8 10.2 0.00094 19.8 1.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS26935.1 - 5.2e-07 29.3 6.9 0.1 12.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS26935.1 - 5.3e-06 26.5 0.8 0.0023 18.0 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS26935.1 - 0.00028 21.3 8.1 53 4.8 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDS26935.1 - 0.014 15.4 0.2 0.46 10.5 0.0 3.1 3 1 0 3 3 3 0 Putative TPR-like repeat TPR_20 PF14561.6 CDS26935.1 - 0.028 14.7 0.2 4.8 7.6 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 CDS26935.1 - 0.17 10.5 0.0 0.87 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 CDS26935.1 - 0.37 10.1 3.3 69 2.7 0.2 3.8 3 2 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 CDS26935.1 - 0.67 9.9 11.7 11 6.0 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat T-box PF00907.22 CDS26938.2 - 1.7e-115 383.7 9.8 4.5e-69 232.4 1.4 2.4 2 0 0 2 2 2 2 T-box Annexin_like PF18411.1 CDS26938.2 - 0.077 13.3 0.0 25 5.2 0.0 2.6 2 0 0 2 2 2 0 Annexin-like domain HDC PF02329.16 CDS26938.2 - 0.16 11.0 0.0 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 Histidine carboxylase PI chain Porin_3 PF01459.22 CDS26940.1 - 1.3e-50 172.4 0.8 1.5e-50 172.2 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF72 PF01904.18 CDS26940.1 - 0.038 14.1 0.0 0.086 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF72 CwfJ_C_1 PF04677.15 CDS26941.1 - 1e-31 109.3 0.0 2.2e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CDS26941.1 - 1.3e-12 48.5 0.0 4.5e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 WD40 PF00400.32 CDS26942.2 - 0.013 16.3 7.5 26 5.9 0.2 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat 7tm_1 PF00001.21 CDS26943.1 - 7.7e-73 245.0 6.0 1.1e-72 244.6 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS26943.1 - 1.4e-09 37.8 16.5 3.6e-06 26.6 12.7 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS26943.1 - 0.0001 22.0 12.9 0.00027 20.7 12.9 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1980 PF09323.10 CDS26943.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LST1 PF05083.13 CDS26943.1 - 2.3 8.6 4.8 0.77 10.1 0.3 2.6 2 1 0 2 2 2 0 LST-1 protein 7tm_4 PF13853.6 CDS26943.1 - 3.7 7.2 16.5 1.9 8.1 8.8 2.6 2 1 1 3 3 3 0 Olfactory receptor PseudoU_synth_2 PF00849.22 CDS26944.1 - 1.7e-25 90.0 0.0 3.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase 7tm_1 PF00001.21 CDS26945.1 - 4.8e-55 186.7 0.0 5e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS26945.1 - 1.3e-12 47.7 12.0 1.8e-12 47.2 12.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS26945.1 - 3.2e-10 40.1 15.5 7.5e-10 38.9 15.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDS26945.1 - 0.015 15.1 8.0 0.023 14.4 8.0 1.3 1 0 0 1 1 1 0 Olfactory receptor Sensor_TM1 PF13755.6 CDS26947.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain YgaB PF14182.6 CDS26947.1 - 0.58 10.6 5.5 0.15 12.4 1.6 1.9 2 1 0 2 2 2 0 YgaB-like protein ALMS_motif PF15309.6 CDS26948.1 - 0.023 15.2 16.1 0.49 10.8 16.1 2.9 1 1 0 1 1 1 0 ALMS motif DUF4058 PF13267.6 CDS26948.1 - 9.8 5.5 8.3 0.76 9.1 2.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4058) PS_Dcarbxylase PF02666.15 CDS26949.1 - 2.3e-55 187.3 0.0 2.8e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 CDS26949.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme G-gamma PF00631.22 CDS26950.2 - 1.5e-10 40.9 0.0 3.8e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 GGL domain FPP PF05911.11 CDS26950.2 - 0.11 10.7 0.6 0.17 10.0 0.6 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1351 PF07083.11 CDS26950.2 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) BCDHK_Adom3 PF10436.9 CDS26950.2 - 0.16 11.8 3.1 0.086 12.7 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase WBP-1 PF11669.8 CDS26950.2 - 1.1 9.9 4.8 7.5 7.2 1.1 2.8 2 0 0 2 2 2 0 WW domain-binding protein 1 Shisa PF13908.6 CDS26950.2 - 1.2 9.4 4.0 0.31 11.3 0.6 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2569 PF10754.9 CDS26950.2 - 2 8.8 6.1 4.6 7.7 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) MRP-S33 PF08293.11 CDS26951.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 HTH_10 PF04967.12 CDS26951.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Brix PF04427.18 CDS26952.2 - 0.0064 16.6 0.5 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Brix domain Hamartin PF04388.12 CDS26952.2 - 0.013 14.2 10.4 0.014 14.1 10.4 1.2 1 0 0 1 1 1 0 Hamartin protein MDM10 PF12519.8 CDS26952.2 - 0.11 11.3 9.3 0.16 10.8 9.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TPR_1 PF00515.28 CDS26953.1 - 1.1e-13 50.3 1.3 1.3e-05 24.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS26953.1 - 7.1e-13 48.0 6.9 3e-07 30.0 0.4 3.4 2 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.6 CDS26953.1 - 3.9e-09 36.3 1.3 0.039 14.4 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS26953.1 - 5.7e-09 35.4 4.1 0.00037 20.4 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS26953.1 - 2.1e-08 34.2 1.9 4.3e-06 26.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS26953.1 - 2e-07 30.7 0.9 0.00049 20.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS26953.1 - 2.4e-07 31.0 2.4 0.021 15.6 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS26953.1 - 1.3e-05 25.7 4.0 0.002 18.7 0.2 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat S1 PF00575.23 CDS26953.1 - 0.0012 19.1 0.0 0.0048 17.2 0.0 2.0 2 0 0 2 2 2 1 S1 RNA binding domain TPR_19 PF14559.6 CDS26953.1 - 0.0013 19.2 6.4 0.44 11.1 0.2 3.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS26953.1 - 0.0034 17.7 1.7 0.0034 17.7 1.7 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat bZIP_1 PF00170.21 CDS26954.1 - 1e-12 47.9 15.2 1e-12 47.9 15.2 2.1 3 0 0 3 3 2 1 bZIP transcription factor bZIP_2 PF07716.15 CDS26954.1 - 8.5e-08 32.2 13.5 8.5e-08 32.2 13.5 1.7 2 0 0 2 2 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS26954.1 - 1.7e-05 25.2 12.0 4.1e-05 24.0 12.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 CDS26954.1 - 0.00076 19.5 2.5 0.0017 18.4 2.5 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF4404 PF14357.6 CDS26954.1 - 0.0075 16.9 0.8 0.0075 16.9 0.8 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4404) ZapB PF06005.12 CDS26954.1 - 0.014 15.8 2.2 0.037 14.5 2.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB V_ATPase_I PF01496.19 CDS26954.1 - 0.36 8.7 5.8 0.56 8.1 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CDS26954.1 - 0.55 10.0 6.0 1.4 8.8 6.0 1.7 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 CDS26954.1 - 0.56 10.9 4.6 0.58 10.8 3.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF724 PF05266.14 CDS26954.1 - 0.67 9.8 9.5 1.2 8.9 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LMBR1 PF04791.16 CDS26954.1 - 1.5 7.6 5.2 2.3 7.0 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Miga PF10265.9 CDS26954.1 - 1.8 7.4 7.3 2.8 6.8 7.3 1.2 1 0 0 1 1 1 0 Mitoguardin Fmp27_WPPW PF10359.9 CDS26954.1 - 2.3 6.9 11.1 4.2 6.1 11.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1635 PF07795.11 CDS26954.1 - 3.4 7.5 11.4 0.18 11.6 5.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Coiled-coil_56 PF09813.9 CDS26955.1 - 7e-06 26.0 0.0 7.9e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Tegument_dsDNA PF12818.7 CDS26955.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF89 PF01937.19 CDS26957.1 - 3.1e-24 85.6 0.0 4.1e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Nif11 PF07862.11 CDS26958.1 - 0.039 14.3 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Nif11 domain UQ_con PF00179.26 CDS26959.1 - 7.8e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Frataxin_Cyay PF01491.16 CDS26959.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Frataxin-like domain SHIPPO-rpt PF07004.12 CDS26959.1 - 1.7 9.7 12.9 1.5 9.9 0.6 4.6 5 0 0 5 5 5 0 Sperm-tail PG-rich repeat Filament PF00038.21 CDS26960.1 - 0.00097 18.8 24.9 0.021 14.4 5.6 2.5 2 0 0 2 2 2 2 Intermediate filament protein HalX PF08663.10 CDS26960.1 - 0.43 10.9 30.9 0.035 14.4 2.9 5.7 4 2 2 6 6 6 0 HalX domain TPR_MLP1_2 PF07926.12 CDS26960.1 - 0.61 10.1 39.2 2.3 8.3 10.7 4.3 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CDS26960.1 - 5.7 7.6 27.9 3.8 8.2 5.2 5.1 3 1 2 5 5 5 0 Initiation control protein YabA Fez1 PF06818.15 CDS26960.1 - 7.2 7.0 43.8 1.6 9.2 10.5 3.4 1 1 1 3 3 3 0 Fez1 KH_1 PF00013.29 CDS26961.1 - 1.4e-24 85.7 0.3 3.6e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDS26961.1 - 3.8e-10 39.4 0.0 4.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDS26961.1 - 0.00047 20.0 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 2 KH domain DUF4947 PF16305.5 CDS26961.1 - 0.053 13.5 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) KH_5 PF13184.6 CDS26961.1 - 0.062 13.4 0.1 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 NusA-like KH domain DUF1173 PF06666.11 CDS26962.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Aldo_ket_red PF00248.21 CDS26963.1 - 1.4e-50 172.1 0.0 5.2e-50 170.3 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDS26964.1 - 4.3e-48 164.0 0.0 1e-47 162.8 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4449 PF14613.6 CDS26964.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) GPW_gp25 PF04965.14 CDS26964.1 - 0.14 12.0 0.0 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Gene 25-like lysozyme Exo_endo_phos_2 PF14529.6 CDS26966.1 - 1.4e-09 37.8 0.4 3.5e-09 36.5 0.4 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS26966.1 - 0.0096 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Perm-CXXC PF15629.6 CDS26966.1 - 0.14 12.5 3.5 0.22 11.8 0.8 2.2 2 0 0 2 2 2 0 Permuted single zf-CXXC unit Aldo_ket_red PF00248.21 CDS26967.1 - 4.1e-50 170.6 0.0 9.6e-50 169.4 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDS26969.2 - 4.6e-52 177.0 0.1 1.1e-51 175.8 0.1 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDS26970.2 - 4.5e-52 177.1 0.0 1.1e-51 175.8 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family NAD_binding_1 PF00175.21 CDS26970.2 - 0.14 12.9 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Aldo_ket_red PF00248.21 CDS26971.1 - 1.2e-53 182.3 0.0 3.1e-53 180.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family CLN3 PF02487.17 CDS26972.2 - 3.2e-29 102.2 1.4 3.6e-29 102.0 1.4 1.0 1 0 0 1 1 1 1 CLN3 protein eIF_4EBP PF05456.11 CDS26973.1 - 0.081 12.9 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CLN3 PF02487.17 CDS26974.1 - 2.7e-73 247.3 3.1 3.4e-73 247.0 3.1 1.0 1 0 0 1 1 1 1 CLN3 protein Mito_fiss_reg PF05308.11 CDS26975.1 - 0.00067 19.8 1.7 0.00067 19.8 1.7 2.9 2 1 1 3 3 3 1 Mitochondrial fission regulator CAP_N PF01213.19 CDS26975.1 - 0.0036 16.9 3.0 0.012 15.2 3.0 1.9 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Homeobox_KN PF05920.11 CDS26976.1 - 3.9e-16 58.7 1.1 7.9e-16 57.7 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS26976.1 - 6.1e-07 29.2 1.7 1.2e-06 28.3 1.7 1.5 1 0 0 1 1 1 1 Homeodomain Podoplanin PF05808.11 CDS26978.1 - 0.007 16.5 3.2 0.01 16.0 3.2 1.3 1 0 0 1 1 1 1 Podoplanin DUF347 PF03988.12 CDS26978.1 - 0.027 14.6 0.8 0.16 12.2 0.0 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Orf78 PF06024.12 CDS26978.1 - 0.75 10.1 3.4 3.4 8.0 3.4 2.1 1 1 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 CDS26978.1 - 5 6.9 7.7 12 5.7 7.7 1.5 1 1 0 1 1 1 0 Rifin COMPASS-Shg1 PF05205.12 CDS26980.1 - 2 9.2 5.8 0.86 10.4 0.6 2.4 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 dNK PF01712.19 CDS26981.1 - 9.7e-22 77.8 0.0 1.1e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase G-alpha PF00503.20 CDS26981.1 - 0.0017 17.6 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_28 PF13521.6 CDS26981.1 - 0.02 15.1 0.0 0.021 15.0 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS26981.1 - 0.037 14.3 0.0 0.044 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDS26981.1 - 0.041 14.4 0.0 0.05 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CDS26981.1 - 0.053 13.4 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 CDS26981.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 CDS26981.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 CDS26981.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 CDS26981.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.22 CDS26983.2 - 1.4e-16 60.1 0.0 1.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS26983.2 - 0.00025 20.8 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Phage_CII PF05269.11 CDS26983.2 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CII protein Headcase PF16002.5 CDS26985.2 - 1.8e-49 167.9 11.4 2.7e-24 85.8 0.0 3.3 2 1 0 2 2 2 2 Headcase protein DiS_P_DiS PF06750.13 CDS26985.2 - 0.093 12.9 4.8 0.69 10.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain Peptidase_M16 PF00675.20 CDS26986.2 - 5.3e-15 55.7 0.0 8.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDS26986.2 - 0.0024 17.9 0.0 0.0096 15.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain HABP4_PAI-RBP1 PF04774.15 CDS26988.2 - 2.9e-15 57.1 8.1 2.9e-15 57.1 8.1 3.9 3 1 0 3 3 3 2 Hyaluronan / mRNA binding family DIE2_ALG10 PF04922.12 CDS26989.1 - 5e-97 325.7 25.4 6.2e-97 325.4 25.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family DUF866 PF05907.13 CDS26990.1 - 2.3e-51 173.8 0.1 2.5e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn-ribbon_8 PF09723.10 CDS26990.1 - 0.012 15.7 1.9 0.24 11.5 1.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain PyrI_C PF02748.15 CDS26990.1 - 0.026 14.4 0.9 0.15 12.0 1.0 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_2 PF13240.6 CDS26990.1 - 0.051 13.3 2.2 8 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.13 CDS26990.1 - 0.084 12.9 0.3 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Nudix_N_2 PF14803.6 CDS26990.1 - 0.085 12.8 0.9 7.6 6.6 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 CDS26990.1 - 0.087 12.4 1.2 8.8 5.9 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding RNHCP PF12647.7 CDS26990.1 - 0.12 12.4 0.4 4.8 7.2 0.1 2.4 1 1 1 2 2 2 0 RNHCP domain RINGv PF12906.7 CDS26991.2 - 2.5e-15 56.3 8.2 2.5e-15 56.3 8.2 2.0 3 0 0 3 3 3 1 RING-variant domain zf-RING_2 PF13639.6 CDS26991.2 - 0.056 13.8 7.9 0.17 12.2 7.9 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CDS26991.2 - 0.24 11.3 4.5 1.4 8.9 4.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M28 PF04389.17 CDS26992.1 - 1.2e-17 64.2 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 LRR_8 PF13855.6 CDS26993.1 - 1.2e-19 69.8 7.5 4e-07 29.7 0.4 3.8 1 1 2 3 3 3 3 Leucine rich repeat Ig_3 PF13927.6 CDS26993.1 - 5e-10 39.8 0.0 1.4e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDS26993.1 - 7e-09 35.9 0.0 2.7e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 CDS26993.1 - 3.7e-08 33.5 7.1 0.00048 20.4 0.5 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) I-set PF07679.16 CDS26993.1 - 4.3e-08 33.1 0.0 7.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CDS26993.1 - 1.2e-06 28.6 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 CDS26993.1 - 1.5e-05 24.9 16.0 0.29 11.8 0.2 7.0 7 0 0 7 7 5 1 Leucine Rich Repeat V-set PF07686.17 CDS26993.1 - 0.00042 20.4 0.4 0.027 14.6 0.1 3.0 1 1 1 2 2 2 1 Immunoglobulin V-set domain LRR_5 PF13306.6 CDS26993.1 - 0.0013 18.7 0.2 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) C1-set PF07654.15 CDS26993.1 - 0.019 15.4 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Tnp_P_element PF12017.8 CDS26993.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Transposase protein LRR_9 PF14580.6 CDS26993.1 - 0.052 13.0 0.5 0.097 12.2 0.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 CDS26993.1 - 9.4 6.6 13.2 8.9 6.7 0.1 5.1 7 0 0 7 7 7 0 Leucine Rich repeat Phospholip_A2_2 PF05826.12 CDS26994.1 - 0.0012 19.0 0.2 0.037 14.2 0.0 2.1 1 1 0 2 2 2 1 Phospholipase A2 Yae1_N PF09811.9 CDS26994.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Glyco_hydro_18 PF00704.28 CDS26995.1 - 9.3e-15 55.1 0.0 1.1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cpn60_TCP1 PF00118.24 CDS26996.1 - 4.1e-155 517.1 16.8 4.7e-155 517.0 16.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family partial_CstF PF15861.5 CDS26996.1 - 0.027 14.3 0.1 0.21 11.4 0.1 2.5 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain SBDS_C PF09377.10 CDS26996.1 - 2 8.4 5.5 0.85 9.6 2.3 2.0 2 1 0 2 2 2 0 SBDS protein C-terminal domain Myb_DNA-bind_4 PF13837.6 CDS26998.1 - 1.5e-08 34.9 0.5 3e-08 33.9 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CDS26998.1 - 0.0011 19.3 0.7 0.0031 17.8 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 CDS26998.1 - 0.0015 18.7 0.9 0.003 17.7 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS26998.1 - 0.0032 17.7 0.3 0.01 16.0 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3402 PF11882.8 CDS26999.1 - 1.1e-94 318.2 18.9 5.8e-60 203.7 5.1 3.7 2 1 2 4 4 4 3 Domain of unknown function (DUF3402) N1221 PF07923.13 CDS26999.1 - 2.7e-35 122.0 0.0 5.2e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 N1221-like protein Pkinase PF00069.25 CDS26999.1 - 8.1e-15 54.9 0.0 4.3e-10 39.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS26999.1 - 8.2e-09 35.1 0.0 2.3e-06 27.1 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase HSP70 PF00012.20 CDS27000.1 - 2.8e-215 716.0 1.4 3.3e-215 715.8 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDS27000.1 - 2.6e-15 56.1 0.8 9.9e-11 41.0 0.5 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CDS27000.1 - 1.6e-05 24.7 0.0 4.3e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CDS27000.1 - 0.004 17.6 0.1 2.1 8.8 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA Synaptobrevin PF00957.21 CDS27000.1 - 0.056 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin TLE_N PF03920.15 CDS27001.1 - 2.6e-48 163.4 5.2 4.8e-48 162.5 5.2 1.4 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 CDS27001.1 - 3.3e-13 49.9 19.0 0.018 15.9 1.6 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_3 PF13570.6 CDS27001.1 - 0.098 13.2 0.1 38 4.9 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain TORC_N PF12884.7 CDS27001.1 - 0.28 12.0 0.1 0.28 12.0 0.1 3.6 4 0 0 4 4 4 0 Transducer of regulated CREB activity, N terminus WD40 PF00400.32 CDS27002.1 - 1.7e-15 57.1 10.5 3.4e-05 24.5 0.4 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27002.1 - 1.7e-11 44.2 0.2 0.00055 20.2 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS27002.1 - 0.00056 19.8 0.5 1.8 8.4 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 CDS27002.1 - 0.067 12.2 0.0 7.1 5.6 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 CDS27002.1 - 0.068 11.7 0.0 0.36 9.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 CDS27002.1 - 0.17 10.8 1.2 23 3.8 0.0 3.2 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain CDC45 PF02724.14 CDS27002.1 - 0.27 9.5 3.2 0.38 9.0 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Meis_PKNOX_N PF16493.5 CDS27005.1 - 8.4e-34 115.8 0.2 1.4e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 Homeobox_KN PF05920.11 CDS27005.1 - 8.1e-20 70.4 0.4 2e-19 69.2 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS27005.1 - 8.2e-08 32.0 0.2 1.7e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Homeodomain DUF3346 PF11826.8 CDS27006.1 - 0.0045 16.8 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3346) SRPRB PF09439.10 CDS27007.1 - 1.1e-28 99.9 0.1 1.4e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CDS27007.1 - 8.2e-09 35.1 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CDS27007.1 - 0.00027 20.8 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CH PF00307.31 CDS27008.2 - 8.9e-29 99.9 7.8 9.3e-17 61.2 0.0 6.5 6 1 1 7 7 7 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS27008.2 - 0.0071 16.2 0.6 0.62 9.9 0.0 3.8 3 0 0 3 3 3 1 CAMSAP CH domain IKKbetaNEMObind PF12179.8 CDS27008.2 - 0.38 10.8 5.4 3.1 7.9 0.5 5.5 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain MetOD1 PF18546.1 CDS27008.2 - 3.6 7.6 9.3 1.2 9.0 0.7 4.1 3 0 0 3 3 3 0 Metanogen output domain 1 Methyltransf_28 PF02636.17 CDS27009.1 - 3.6e-62 210.4 0.0 4.5e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CLASP_N PF12348.8 CDS27010.1 - 2.9e-36 125.2 7.2 1.6e-31 109.7 0.0 4.0 3 1 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 CDS27010.1 - 2.3e-10 39.8 4.3 0.014 15.6 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CDS27010.1 - 6.6e-07 29.7 0.3 0.0039 17.7 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDS27010.1 - 4.9e-06 27.0 0.6 0.42 11.3 0.0 5.0 2 2 2 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDS27010.1 - 0.00039 20.5 9.1 0.84 9.7 1.6 5.2 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CDS27010.1 - 0.0004 19.6 2.3 1.1 8.4 0.0 3.5 2 1 2 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 CDS27010.1 - 0.00062 18.4 11.9 0.84 8.1 0.3 5.5 3 3 1 5 5 5 3 Adaptin N terminal region HEAT_2 PF13646.6 CDS27010.1 - 0.0035 17.7 7.0 3.4 8.1 0.3 5.2 6 1 1 7 7 7 2 HEAT repeats IFRD PF05004.13 CDS27010.1 - 0.0035 16.5 3.7 0.023 13.8 1.6 2.8 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CDS27010.1 - 0.0097 16.1 1.5 1.5 9.0 0.3 4.3 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 CDS27010.1 - 0.016 15.4 0.3 0.86 9.7 0.1 2.8 1 1 1 2 2 2 0 Parkin co-regulated protein MMS19_N PF14500.6 CDS27010.1 - 0.055 13.1 0.0 2.2 7.8 0.0 2.9 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Sec7_N PF12783.7 CDS27010.1 - 0.065 13.1 4.4 7.8 6.4 0.1 3.6 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_N PF03224.14 CDS27010.1 - 0.092 12.0 2.5 0.3 10.3 0.2 2.4 1 1 0 2 2 2 0 V-ATPase subunit H Atg14 PF10186.9 CDS27011.1 - 0.003 16.7 5.8 0.0039 16.3 5.8 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG17 PF04108.12 CDS27011.1 - 0.0039 16.4 2.7 0.0052 16.0 2.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Borrelia_REV PF03978.13 CDS27011.1 - 0.013 15.4 2.4 0.02 14.9 2.4 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Jnk-SapK_ap_N PF09744.9 CDS27011.1 - 0.098 12.9 10.8 0.13 12.4 10.0 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FapA PF03961.13 CDS27011.1 - 0.11 11.0 2.9 0.14 10.7 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 CDS27011.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 CDS27011.1 - 0.17 12.0 6.5 0.25 11.4 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GARP PF16731.5 CDS27011.1 - 0.18 11.5 6.5 0.52 10.0 2.5 2.1 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma YabA PF06156.13 CDS27011.1 - 0.95 10.1 6.2 11 6.7 1.1 2.2 1 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 CDS27011.1 - 1.2 9.4 9.2 4 7.7 0.1 3.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper ZapB PF06005.12 CDS27011.1 - 2.2 8.8 12.6 7.2 7.1 1.8 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Rho_Binding PF08912.11 CDS27011.1 - 3.2 8.6 10.2 3.9 8.4 0.8 2.4 1 1 0 2 2 2 0 Rho Binding Spc7 PF08317.11 CDS27011.1 - 3.9 6.3 11.8 7.8 5.3 11.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 CDS27011.1 - 7.8 6.1 9.5 1.3 8.7 0.5 2.2 1 1 1 2 2 2 0 GrpE fn3 PF00041.21 CDS27013.2 - 8.1e-58 192.7 24.4 1.3e-14 54.3 0.2 10.5 9 3 0 9 9 9 6 Fibronectin type III domain I-set PF07679.16 CDS27013.2 - 6.4e-34 115.9 0.0 6.9e-12 45.3 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS27013.2 - 9.3e-32 109.5 0.2 4.9e-12 46.3 0.0 5.0 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.25 CDS27013.2 - 4.1e-19 68.6 0.0 1.3e-05 25.3 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDS27013.2 - 1.9e-16 60.2 0.0 1e-06 28.9 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDS27013.2 - 2.7e-13 50.3 3.7 0.0012 19.4 0.0 6.7 7 0 0 7 7 7 2 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CDS27013.2 - 2.4e-07 30.9 0.2 0.00084 19.5 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS27013.2 - 0.0066 16.5 0.8 0.51 10.4 0.1 3.4 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Med21 PF11221.8 CDS27014.1 - 0.19 11.9 3.9 0.36 11.1 3.9 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TCTP PF00838.17 CDS27015.1 - 3.3e-52 177.2 0.3 3.7e-52 177.0 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CarboxypepD_reg PF13620.6 CDS27016.1 - 2.5e-27 95.0 9.8 1.5e-06 28.3 0.0 9.3 9 1 0 9 9 9 4 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 CDS27016.1 - 3.4e-10 40.1 0.1 5.7 7.2 0.0 7.7 6 1 1 8 8 8 1 SdrD B-like domain CarbopepD_reg_2 PF13715.6 CDS27016.1 - 4.6e-10 39.3 2.2 6.6e-05 22.8 0.0 5.9 8 0 0 8 8 8 2 CarboxypepD_reg-like domain DUF2012 PF09430.10 CDS27016.1 - 1e-08 35.3 0.5 0.2 11.8 0.0 5.9 7 0 0 7 7 7 2 Protein of unknown function (DUF2012) Y_Y_Y PF07495.13 CDS27016.1 - 2.1e-06 27.6 0.6 5.9 6.9 0.0 5.9 6 0 0 6 6 6 2 Y_Y_Y domain SpaA PF17802.1 CDS27016.1 - 3.2e-06 27.4 0.0 2.5 8.5 0.0 5.9 8 0 0 8 8 8 2 Prealbumin-like fold domain fn3_3 PF14686.6 CDS27016.1 - 1.8e-05 24.4 0.1 10 6.0 0.1 4.9 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain II MetallophosN PF16371.5 CDS27016.1 - 0.0024 18.1 0.0 0.14 12.4 0.0 3.3 3 0 0 3 3 3 1 N terminal of Calcineurin-like phosphoesterase CooC_C PF15976.5 CDS27016.1 - 0.0038 17.3 0.0 0.25 11.4 0.0 3.0 2 0 0 2 2 2 1 CS1-pili formation C-terminal Pollen_Ole_e_I PF01190.17 CDS27016.1 - 0.016 15.5 0.0 0.27 11.6 0.0 2.7 2 0 0 2 2 2 0 Pollen proteins Ole e I like CarbpepA_inh PF02977.15 CDS27017.1 - 0.27 11.1 1.8 0.39 10.5 0.3 1.9 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Prominin PF05478.11 CDS27018.2 - 6.9e-53 179.8 28.8 7.4e-34 116.8 10.6 3.3 2 1 0 2 2 2 2 Prominin DUF2207 PF09972.9 CDS27018.2 - 0.0054 15.6 0.1 0.0054 15.6 0.1 3.0 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) Promethin PF16015.5 CDS27018.2 - 0.0069 16.3 0.9 0.0069 16.3 0.9 3.4 4 0 0 4 4 4 1 Promethin GCN5L1 PF06320.13 CDS27018.2 - 0.064 13.4 1.5 20 5.3 0.0 3.5 3 1 1 4 4 4 0 GCN5-like protein 1 (GCN5L1) Translin PF01997.16 CDS27018.2 - 0.092 12.7 0.5 0.33 10.9 0.0 2.1 2 1 0 2 2 2 0 Translin family YtxH PF12732.7 CDS27018.2 - 0.25 11.9 1.7 4.6 7.9 0.0 3.4 3 0 0 3 3 3 0 YtxH-like protein Baculo_PEP_C PF04513.12 CDS27018.2 - 1.1 9.2 12.4 4.7 7.2 3.5 3.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 CDS27018.2 - 4.1 7.9 6.6 5 7.6 0.9 3.3 2 2 1 4 4 4 0 Snapin/Pallidin DotD PF16816.5 CDS27019.1 - 0.01 15.8 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 DotD protein Get5_bdg PF16843.5 CDS27019.1 - 0.058 12.9 0.0 13 5.3 0.0 2.9 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein SNN_linker PF09050.10 CDS27020.1 - 0.014 15.2 1.5 0.053 13.3 1.5 2.0 1 0 0 1 1 1 0 Stannin unstructured linker DUF3863 PF12979.7 CDS27020.1 - 0.05 12.5 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Y_phosphatase PF00102.27 CDS27021.2 - 2.5e-06 27.3 0.1 3e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 CDS27023.2 - 0.003 17.1 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase rve PF00665.26 CDS27028.1 - 1.8e-11 44.2 0.0 2.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS27028.1 - 0.00043 20.0 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain SH3_11 PF18103.1 CDS27028.1 - 0.041 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain Y_phosphatase PF00102.27 CDS27029.2 - 0.059 12.9 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 CDS27030.2 - 1.5e-06 27.9 0.1 1.6e-06 27.9 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.21 CDS27032.1 - 1.1e-09 38.5 7.1 0.0022 18.3 3.3 3.2 3 0 0 3 3 3 2 Fibronectin type III domain ig PF00047.25 CDS27032.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 CDS27032.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 CDS27032.1 - 0.16 12.1 0.0 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin I-set domain Metal_resist PF13801.6 CDS27033.1 - 8.3e-05 22.8 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal resistance Cnn_1N PF07989.11 CDS27033.1 - 0.02 15.0 14.3 1.1 9.5 0.2 3.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 CDS27033.1 - 0.5 10.6 5.4 8.4 6.6 0.2 3.0 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II CENP-H PF05837.12 CDS27033.1 - 1.2 9.6 6.6 4.5 7.7 6.6 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Rx_N PF18052.1 CDS27033.1 - 3.6 7.9 6.9 1.4 9.3 1.2 3.0 3 1 1 4 4 4 0 Rx N-terminal domain Cadherin PF00028.17 CDS27034.1 - 2e-70 233.3 0.0 1.3e-10 41.6 0.0 9.5 7 3 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS27034.1 - 2.4e-09 36.9 0.0 3.9e-05 23.4 0.0 5.0 5 0 0 5 5 5 2 Cadherin-like DSL PF01414.19 CDS27036.1 - 5.5e-09 36.2 4.8 5.5e-09 36.2 4.8 4.4 3 1 1 4 4 4 1 Delta serrate ligand EGF PF00008.27 CDS27036.1 - 2.1e-08 34.3 39.3 1e-05 25.7 4.9 5.3 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 CDS27036.1 - 0.0061 17.2 2.4 0.0061 17.2 2.4 5.4 5 0 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 CDS27036.1 - 0.02 15.2 7.5 0.02 15.2 7.5 5.6 6 0 0 6 6 6 0 EGF-like domain C2 PF00168.30 CDS27036.1 - 0.027 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain Adeno_E3_CR2 PF02439.15 CDS27036.1 - 0.094 12.5 3.5 0.23 11.3 3.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM52 PF14979.6 CDS27036.1 - 0.11 12.4 2.8 0.36 10.7 2.8 1.9 1 0 0 1 1 1 0 Transmembrane 52 DSL PF01414.19 CDS27037.2 - 3.3e-11 43.3 7.8 3.3e-11 43.3 7.8 3.8 2 1 1 3 3 3 1 Delta serrate ligand EGF PF00008.27 CDS27037.2 - 3e-08 33.8 17.4 7.1e-06 26.2 2.4 5.0 4 1 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 CDS27037.2 - 0.0002 21.6 21.0 0.00036 20.8 8.2 5.8 6 1 0 6 6 6 2 EGF-like domain hEGF PF12661.7 CDS27037.2 - 0.00036 21.1 4.6 0.00036 21.1 4.6 5.8 6 1 0 6 6 6 2 Human growth factor-like EGF EGF_3 PF12947.7 CDS27037.2 - 0.0027 17.9 27.2 0.0093 16.1 1.9 4.1 4 0 0 4 4 4 2 EGF domain DUF2561 PF10812.8 CDS27037.2 - 0.043 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3827 PF12877.7 CDS27037.2 - 0.21 9.9 0.0 0.33 9.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF5385 PF17359.2 CDS27037.2 - 0.48 9.9 1.3 0.82 9.2 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SKG6 PF08693.10 CDS27037.2 - 1.2 8.6 7.5 2.5 7.6 7.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Romo1 PF10247.9 CDS27038.2 - 2.6 8.5 5.6 17 5.8 3.1 2.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 BcrAD_BadFG PF01869.20 CDS27039.1 - 1.3e-14 54.4 0.0 1.5e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_2 PF03727.16 CDS27039.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Hexokinase Peptidase_M41 PF01434.18 CDS27040.1 - 5.5e-58 196.0 0.0 9.3e-58 195.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDS27040.1 - 7.3e-40 136.5 0.0 1.7e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS27040.1 - 1.1e-10 41.1 0.0 8.2e-10 38.3 0.0 2.4 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 CDS27040.1 - 6.5e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS27040.1 - 0.0001 22.7 1.2 0.00056 20.3 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CDS27040.1 - 0.0002 21.1 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDS27040.1 - 0.00071 19.9 0.0 0.016 15.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CDS27040.1 - 0.0026 17.0 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CDS27040.1 - 0.0026 17.9 0.0 0.0075 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDS27040.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDS27040.1 - 0.0071 16.4 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDS27040.1 - 0.025 14.0 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CDS27040.1 - 0.032 14.3 0.0 0.089 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CDS27040.1 - 0.039 14.5 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDS27040.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CDS27040.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CDS27040.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain HrpB7 PF09486.10 CDS27041.2 - 0.00015 22.2 1.5 0.24 11.8 0.1 2.3 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 CDS27041.2 - 0.00045 19.2 13.2 0.0017 17.3 5.8 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 CDS27041.2 - 0.0039 17.4 6.7 0.0039 17.4 6.7 3.1 3 0 0 3 3 2 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 CDS27041.2 - 0.0054 15.7 9.0 0.22 10.3 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF812) ERM PF00769.19 CDS27041.2 - 0.0072 16.2 7.9 0.3 10.9 3.5 2.2 2 0 0 2 2 2 2 Ezrin/radixin/moesin family UPF0242 PF06785.11 CDS27041.2 - 0.012 15.7 3.6 0.012 15.7 3.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2508 PF10704.9 CDS27041.2 - 0.02 15.0 2.4 0.02 15.0 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) NYD-SP28 PF14772.6 CDS27041.2 - 0.03 14.4 7.2 0.22 11.6 7.2 2.3 1 1 0 1 1 1 0 Sperm tail SYCE1 PF15233.6 CDS27041.2 - 0.034 14.2 12.8 3.6 7.6 5.3 3.3 3 0 0 3 3 3 0 Synaptonemal complex central element protein 1 Syntaxin-6_N PF09177.11 CDS27041.2 - 0.039 14.5 13.5 0.095 13.3 2.2 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 CDS27041.2 - 0.05 14.2 15.3 0.16 12.6 0.7 3.0 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 CDS27041.2 - 0.087 12.1 10.8 0.3 10.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DASH_Duo1 PF08651.10 CDS27041.2 - 0.14 12.0 8.4 0.04 13.7 2.5 2.7 3 0 0 3 3 2 0 DASH complex subunit Duo1 DUF1664 PF07889.12 CDS27041.2 - 0.17 11.9 6.5 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 CDS27041.2 - 0.19 11.7 7.3 0.029 14.3 1.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD HMMR_N PF15905.5 CDS27041.2 - 0.2 11.1 16.8 0.094 12.2 7.8 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF745 PF05335.13 CDS27041.2 - 0.38 10.5 6.0 4.2 7.1 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMF_TATA_bd PF12325.8 CDS27041.2 - 0.39 11.0 10.7 0.95 9.7 3.4 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.15 CDS27041.2 - 0.54 10.4 14.2 0.04 14.1 6.1 2.3 2 0 0 2 2 2 0 RasGAP C-terminus IFT20 PF14931.6 CDS27041.2 - 0.91 9.7 14.1 5.4 7.2 5.6 3.3 3 1 0 3 3 2 0 Intraflagellar transport complex B, subunit 20 APG6_N PF17675.1 CDS27041.2 - 1.1 9.8 15.4 2.7 8.5 7.7 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_N PF10481.9 CDS27041.2 - 1.1 8.9 12.0 0.15 11.7 5.8 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain HemX PF04375.14 CDS27041.2 - 1.3 8.3 10.0 0.077 12.3 2.2 2.4 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fez1 PF06818.15 CDS27041.2 - 1.4 9.3 15.7 6.8 7.1 7.5 2.4 1 1 1 2 2 2 0 Fez1 SlyX PF04102.12 CDS27041.2 - 1.8 9.2 8.4 5.2 7.8 0.4 3.6 2 1 1 3 3 3 0 SlyX ADIP PF11559.8 CDS27041.2 - 2.4 8.3 14.3 6.5 6.8 5.9 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding THOC7 PF05615.13 CDS27041.2 - 2.7 8.3 11.8 2.3 8.5 2.9 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.9 CDS27041.2 - 4.4 7.3 16.9 2.7 8.0 0.7 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 CDS27041.2 - 5 6.3 7.8 5.6 6.1 2.8 2.2 2 0 0 2 2 2 0 TMPIT-like protein DUF4407 PF14362.6 CDS27041.2 - 5.7 6.2 6.4 1.7 7.9 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 CDS27041.2 - 6.1 7.3 16.6 0.35 11.3 9.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.22 CDS27041.2 - 6.8 7.0 9.7 1.7 8.9 4.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 CDS27041.2 - 8.3 6.9 8.6 18 5.8 0.1 3.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 CDS27041.2 - 8.3 4.9 10.1 1.8 7.1 3.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-CCCH PF00642.24 CDS27042.1 - 3.8e-06 26.7 21.9 0.0073 16.2 0.8 5.3 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS27042.1 - 2.1e-05 24.4 18.5 0.03 14.4 0.7 5.9 5 1 0 5 5 5 2 Zinc finger domain zf-CCCH_2 PF14608.6 CDS27042.1 - 0.004 17.6 8.8 0.34 11.5 1.7 2.9 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CDS27042.1 - 0.011 16.4 13.9 0.17 12.6 1.9 4.1 1 1 3 4 4 4 0 Torus domain zf_CCCH_5 PF18384.1 CDS27042.1 - 0.11 12.7 5.4 12 6.2 0.0 3.8 2 1 1 3 3 3 0 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH_4 PF18044.1 CDS27042.1 - 0.27 11.1 19.0 0.68 9.8 0.0 4.6 4 1 0 4 4 4 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDS27042.1 - 0.4 10.9 9.0 3.6 7.9 3.2 3.1 1 1 1 2 2 2 0 Zinc-finger containing family ELL PF10390.9 CDS27045.1 - 2.9e-47 161.5 0.0 6e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 CDS27045.1 - 3.5e-17 63.0 2.1 3.5e-17 63.0 2.1 2.0 2 0 0 2 2 2 1 Occludin homology domain IRS PF02174.17 CDS27047.1 - 0.00059 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) MFS_1 PF07690.16 CDS27051.1 - 1e-24 87.2 44.3 2.6e-17 62.8 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ac81 PF05820.11 CDS27052.1 - 0.12 11.9 6.0 0.089 12.4 4.9 1.3 1 1 0 1 1 1 0 Baculoviridae AC81 DUF2070 PF09843.9 CDS27052.1 - 1.6 6.9 16.9 1.9 6.7 16.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0182 PF03699.13 CDS27053.1 - 2.6 6.0 7.5 3.1 5.8 7.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Trp_oprn_chp PF09534.10 CDS27053.1 - 3.9 7.2 9.3 2.1 8.1 7.0 1.7 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Peptidase_U4 PF03419.13 CDS27054.1 - 0.53 9.5 11.8 0.64 9.3 11.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Trp_oprn_chp PF09534.10 CDS27054.1 - 1.4 8.7 8.3 0.083 12.7 3.3 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UPF0182 PF03699.13 CDS27054.1 - 7.3 4.6 8.1 6.1 4.8 7.1 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF1622 PF07784.11 CDS27056.1 - 0.018 14.9 0.7 0.018 14.9 0.7 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1622) LrgA PF03788.14 CDS27058.1 - 0.00074 19.4 8.6 0.0011 18.9 7.4 1.8 1 1 1 2 2 2 2 LrgA family DUF1129 PF06570.11 CDS27058.1 - 0.053 13.0 7.2 0.042 13.3 4.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) YfhO PF09586.10 CDS27058.1 - 0.8 7.9 8.4 1.1 7.5 8.4 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO DUF1772 PF08592.11 CDS27058.1 - 1.1 9.6 5.7 93 3.3 5.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3995 PF13160.6 CDS27058.1 - 6.7 7.1 11.8 20 5.5 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Sigma_reg_N PF13800.6 CDS27058.1 - 9.4 6.6 10.8 17 5.8 0.2 3.3 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Autophagy_N PF03986.13 CDS27059.1 - 1.9e-43 147.7 0.3 3.7e-43 146.8 0.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CDS27059.1 - 1.8e-16 60.4 0.1 3.9e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDS27059.1 - 6e-16 57.6 1.1 1.1e-15 56.8 1.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal GET2 PF08690.10 CDS27059.1 - 4.6 6.8 9.1 0.87 9.2 0.6 2.1 1 1 0 2 2 2 0 GET complex subunit GET2 ARF7EP_C PF14949.6 CDS27060.1 - 1.6e-19 70.5 12.1 3.8e-18 66.0 6.4 2.8 2 1 1 3 3 3 2 ARF7 effector protein C-terminus PTEN_C2 PF10409.9 CDS27061.1 - 1.7e-07 31.1 0.0 3.2e-06 26.9 0.0 2.6 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PTPlike_phytase PF14566.6 CDS27061.1 - 1.8e-06 28.1 0.0 4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 CDS27061.1 - 0.00039 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS27061.1 - 0.0039 17.2 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDS27061.1 - 0.0052 16.4 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EMP70 PF02990.16 CDS27063.1 - 4.5e-198 659.1 13.2 6.1e-198 658.7 13.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 CDS27063.1 - 0.0012 17.9 19.4 0.0012 17.9 19.4 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Jnk-SapK_ap_N PF09744.9 CDS27064.1 - 1.1e-35 123.2 6.7 1.1e-35 123.2 6.7 3.1 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 CDS27064.1 - 7.5e-12 45.2 4.3 7.5e-12 45.2 4.3 3.4 2 2 0 2 2 2 1 JNK-interacting protein leucine zipper II AAA_15 PF13175.6 CDS27064.1 - 0.015 15.0 0.8 0.015 15.0 0.8 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF2711 PF10924.8 CDS27064.1 - 0.02 14.5 0.9 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2711) Spc7 PF08317.11 CDS27064.1 - 0.041 12.8 13.1 0.014 14.3 5.1 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CDS27064.1 - 0.37 10.9 12.8 0.84 9.8 1.1 3.7 4 0 0 4 4 4 0 bZIP transcription factor TMPIT PF07851.13 CDS27064.1 - 9.8 5.3 11.0 1.4 8.1 0.2 2.8 2 1 1 3 3 3 0 TMPIT-like protein Ribosomal_L38e PF01781.18 CDS27065.1 - 2.8e-32 110.6 6.0 3e-32 110.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.17 CDS27065.1 - 0.065 13.7 0.1 0.072 13.5 0.1 1.1 1 0 0 1 1 1 0 Early Protein (E6) Ras PF00071.22 CDS27067.1 - 1.1e-15 57.6 0.2 1.4e-15 57.3 0.2 1.2 1 0 0 1 1 1 1 Ras family IIGP PF05049.13 CDS27067.1 - 0.033 13.2 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EF-hand_7 PF13499.6 CDS27068.1 - 0.0044 17.4 0.6 0.093 13.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CDS27070.2 - 1.2e-08 35.3 0.0 0.004 17.6 0.0 3.7 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_13 PF17958.1 CDS27070.2 - 5.1e-05 23.0 0.0 2.1 8.2 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_6 PF13405.6 CDS27070.2 - 8.5e-05 22.2 0.0 0.19 11.7 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CDS27070.2 - 0.0001 21.6 0.0 0.34 10.6 0.0 3.9 3 0 0 3 3 3 1 EF hand THDPS_N_2 PF14805.6 CDS27070.2 - 0.0035 17.5 0.0 0.14 12.4 0.0 2.8 1 1 2 3 3 3 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal EF-hand_5 PF13202.6 CDS27070.2 - 0.03 13.8 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 EF hand Beach PF02138.18 CDS27071.2 - 8.8e-50 169.6 0.4 1.1e-49 169.3 0.4 1.0 1 0 0 1 1 1 1 Beige/BEACH domain MCM PF00493.23 CDS27072.2 - 9.9e-10 37.9 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain COX5A PF02284.16 CDS27072.2 - 0.058 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va MCM PF00493.23 CDS27073.1 - 1.2e-99 332.0 0.0 1.8e-99 331.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS27073.1 - 7.8e-39 132.4 0.9 1.4e-38 131.6 0.9 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS27073.1 - 9.6e-28 96.4 0.2 2.2e-27 95.3 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDS27073.1 - 8.8e-15 55.2 0.2 1.9e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDS27073.1 - 1.5e-06 27.8 0.0 0.00042 19.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS27073.1 - 3.7e-05 23.8 0.0 9.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDS27073.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDS27073.1 - 0.051 13.3 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain THF_DHG_CYH_C PF02882.19 CDS27073.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rap_GAP PF02145.15 CDS27074.2 - 0.11 12.0 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Rap/ran-GAP PARP PF00644.20 CDS27075.1 - 2.6e-58 196.8 0.1 5.7e-58 195.7 0.0 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDS27075.1 - 1.4e-45 154.8 2.4 1e-43 148.7 0.8 2.4 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 CDS27075.1 - 1.1e-22 80.6 1.6 4.4e-18 65.9 0.1 2.6 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 CDS27075.1 - 8e-20 70.7 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 CDS27075.1 - 8.6e-09 35.0 0.7 9.3e-07 28.5 0.0 3.2 3 0 0 3 3 3 1 PADR1 (NUC008) domain GHMP_kinases_N PF00288.26 CDS27076.1 - 2.6e-10 40.4 1.8 5.5e-10 39.3 1.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDS27076.1 - 4e-08 33.5 0.0 9.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CDS27076.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Phosducin PF02114.16 CDS27076.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosducin COX5A PF02284.16 CDS27077.1 - 1.5e-39 134.2 0.0 1.8e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va FAM195 PF14799.6 CDS27077.1 - 0.047 14.0 0.1 0.068 13.5 0.1 1.3 1 0 0 1 1 1 0 FAM195 family DUF4207 PF13904.6 CDS27078.1 - 6.9e-06 25.9 68.8 2.5e-05 24.1 47.5 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4207) Caldesmon PF02029.15 CDS27078.1 - 0.00097 18.0 34.0 0.0013 17.6 34.0 1.3 1 0 0 1 1 1 1 Caldesmon DUF842 PF05811.13 CDS27079.1 - 9.3e-37 125.6 11.3 1.1e-36 125.4 11.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF4446 PF14584.6 CDS27079.1 - 0.0041 17.1 0.3 0.0071 16.3 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4446) ApoLp-III PF07464.11 CDS27079.1 - 0.0056 16.8 0.4 0.017 15.2 0.2 1.8 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Cor1 PF04803.12 CDS27079.1 - 0.042 14.1 5.2 2.5 8.3 2.4 2.1 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF285 PF03382.14 CDS27079.1 - 0.051 13.3 0.0 0.074 12.8 0.0 1.4 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 CBFD_NFYB_HMF PF00808.23 CDS27079.1 - 0.15 12.4 0.6 0.41 11.0 0.3 1.8 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vicilin_N PF04702.12 CDS27079.1 - 1.6 8.5 15.7 2.7 7.8 15.3 1.6 1 1 0 1 1 1 0 Vicilin N terminal region I-set PF07679.16 CDS27080.1 - 4.1e-54 180.6 0.0 1.6e-13 50.6 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS27080.1 - 1.3e-53 179.5 2.8 3.4e-13 50.0 0.0 6.4 6 0 0 6 6 5 5 Immunoglobulin domain Ig_2 PF13895.6 CDS27080.1 - 2.3e-37 127.2 5.2 6.2e-08 32.9 0.0 6.1 6 0 0 6 6 5 5 Immunoglobulin domain ig PF00047.25 CDS27080.1 - 2.3e-35 120.6 0.1 6.8e-07 29.4 0.0 6.1 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 CDS27080.1 - 2.7e-21 75.8 11.5 4.5e-05 23.6 0.1 8.6 6 3 0 6 6 6 4 Immunoglobulin V-set domain Ig_6 PF18452.1 CDS27080.1 - 3.2e-15 55.4 0.2 0.011 15.3 0.0 5.5 5 0 0 5 5 5 3 Immunoglobulin domain fn3 PF00041.21 CDS27080.1 - 4.2e-15 55.9 0.1 1.7e-05 25.0 0.0 5.5 5 0 0 5 5 5 4 Fibronectin type III domain Izumo-Ig PF16706.5 CDS27080.1 - 5e-08 32.9 0.0 0.23 11.6 0.0 4.4 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CDS27080.1 - 9.5e-08 32.0 4.1 0.0061 16.6 0.0 5.4 6 0 0 6 6 6 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CDS27080.1 - 2.8e-06 27.5 0.2 0.0057 16.9 0.0 4.8 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain C1-set PF07654.15 CDS27080.1 - 0.011 16.0 1.8 8.9 6.8 0.0 4.7 5 1 0 5 5 5 0 Immunoglobulin C1-set domain Orthoreo_P10 PF07204.11 CDS27080.1 - 0.058 13.3 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TPH PF13868.6 CDS27081.1 - 1.1e-14 53.7 117.8 1.1e-14 53.7 117.8 2.0 2 0 0 2 2 2 2 Trichohyalin-plectin-homology domain LIM PF00412.22 CDS27082.1 - 2.4e-13 50.1 8.8 4.1e-13 49.3 8.8 1.4 1 0 0 1 1 1 1 LIM domain SH3_9 PF14604.6 CDS27082.1 - 1.5e-10 40.7 0.1 2.5e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS27082.1 - 1.9e-09 37.0 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Nebulin PF00880.18 CDS27082.1 - 1.6e-06 27.9 0.2 2.9e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Nebulin repeat SH3_2 PF07653.17 CDS27082.1 - 0.00072 19.2 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NUDE_C PF04880.13 CDS27082.1 - 0.13 12.8 0.8 0.18 12.3 0.8 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf_UBZ PF18439.1 CDS27082.1 - 0.29 10.8 3.1 9.3 5.9 0.9 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 CDS27083.1 - 5.1e-08 33.1 64.0 0.1 13.5 2.1 9.8 10 0 0 10 10 10 5 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS27083.1 - 4.1e-07 30.1 65.1 0.095 13.2 2.0 9.7 10 0 0 10 10 10 5 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 CDS27083.1 - 0.00088 19.2 12.1 0.045 13.7 0.6 4.0 3 0 0 3 3 3 2 Zap1 zinc finger 2 zf-C2H2_3rep PF18868.1 CDS27083.1 - 0.0084 16.8 1.0 0.0084 16.8 1.0 3.5 4 0 0 4 4 4 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 CDS27083.1 - 0.012 16.0 47.8 0.024 15.0 0.1 9.1 11 0 0 11 11 11 0 Zinc-finger double domain FOXP-CC PF16159.5 CDS27083.1 - 0.03 15.0 21.9 1 10.1 0.1 5.5 5 2 1 6 6 6 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 CDS27083.1 - 0.041 13.7 8.5 16 5.4 0.0 5.4 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 CDS27083.1 - 0.095 12.8 26.3 0.09 12.9 1.9 4.7 4 1 2 6 6 6 0 Aberrant zinc-finger zf-RING_7 PF02591.15 CDS27083.1 - 0.96 9.7 0.0 0.96 9.7 0.0 3.5 4 0 0 4 4 4 0 C4-type zinc ribbon domain DDHD PF02862.17 CDS27084.1 - 7.4e-47 160.4 0.1 2.2e-46 158.8 0.0 1.9 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 CDS27084.1 - 0.014 16.0 0.3 0.41 11.3 0.0 2.8 1 1 1 2 2 2 0 WWE domain Folate_rec PF03024.14 CDS27085.1 - 1.3e-36 126.0 19.8 1.6e-36 125.8 19.8 1.1 1 0 0 1 1 1 1 Folate receptor family CBM_1 PF00734.18 CDS27085.1 - 0.088 12.8 0.7 0.088 12.8 0.7 3.2 4 0 0 4 4 4 0 Fungal cellulose binding domain ATP-synt_ab PF00006.25 CDS27086.1 - 1.1e-61 208.2 0.0 1.7e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDS27086.1 - 9.9e-22 77.2 0.9 2.2e-21 76.1 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 CDS27086.1 - 0.059 13.7 0.3 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDS27086.1 - 0.065 12.4 1.0 0.084 12.1 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 CDS27086.1 - 0.065 13.7 0.0 1.3 9.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CDS27086.1 - 0.067 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 CDS27086.1 - 0.068 13.0 1.1 0.41 10.5 0.5 2.4 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 CDS27086.1 - 0.074 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 CDS27086.1 - 0.11 12.9 0.0 0.39 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 CDS27086.1 - 0.2 10.8 0.1 0.46 9.7 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Med12-LCEWAV PF12145.8 CDS27087.1 - 7.9e-53 180.0 16.1 1e-36 126.8 0.4 3.5 2 1 1 3 3 3 2 Eukaryotic Mediator 12 subunit domain Mito_carr PF00153.27 CDS27089.1 - 1.8e-12 47.0 1.0 2.4e-09 37.0 0.1 2.5 3 0 0 3 3 3 2 Mitochondrial carrier protein MutS_V PF00488.21 CDS27090.1 - 4.4e-40 137.7 1.2 8.5e-40 136.8 1.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDS27090.1 - 4.6e-18 66.1 0.4 3.5e-17 63.3 0.0 2.6 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDS27090.1 - 7.7e-09 35.8 0.0 1.2e-05 25.5 0.0 2.9 2 0 0 2 2 2 2 MutS family domain IV MutS_II PF05188.17 CDS27090.1 - 2e-05 24.9 0.0 6.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain II Alk_phosphatase PF00245.20 CDS27091.2 - 3.9e-107 358.8 0.0 4.5e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDS27091.2 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1409 PF07197.12 CDS27091.2 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Alk_phosphatase PF00245.20 CDS27093.1 - 2.5e-111 372.6 0.0 2.9e-111 372.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDS27093.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Alk_phosphatase PF00245.20 CDS27094.1 - 1.9e-107 359.8 0.0 2.2e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDS27094.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily HEAT_2 PF13646.6 CDS27095.1 - 3.8e-08 33.6 1.8 3.6 8.1 0.1 6.5 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 CDS27095.1 - 6.9e-08 32.1 29.7 0.0086 16.3 0.0 10.1 10 0 0 10 10 10 3 HEAT repeat Homeobox_KN PF05920.11 CDS27096.1 - 6.4e-10 38.8 0.2 1.2e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS27096.1 - 3.9e-06 26.6 0.0 8.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Yuri_gagarin PF15934.5 CDS27096.1 - 0.0026 17.7 0.3 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 Yuri gagarin pPIWI_RE_Z PF18155.1 CDS27096.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Alpha-amylase PF00128.24 CDS27097.1 - 5.1e-08 32.9 0.0 9.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain TFIIA PF03153.13 CDS27097.1 - 0.91 9.5 3.4 1.4 8.8 3.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CD36 PF01130.21 CDS27099.1 - 3.9e-117 391.7 0.0 4.8e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 CD36 family DnaJ PF00226.31 CDS27100.1 - 4.2e-28 97.3 2.1 6e-28 96.8 2.1 1.2 1 0 0 1 1 1 1 DnaJ domain SRP14 PF02290.15 CDS27101.1 - 1.5e-16 60.6 0.0 1.9e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Sec63 PF02889.16 CDS27101.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Sec63 Brl domain Complex1_30kDa PF00329.19 CDS27102.1 - 4.1e-41 140.4 0.0 5.9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit His_Phos_1 PF00300.22 CDS27103.1 - 1.9e-19 70.1 0.0 2e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Adaptin_N PF01602.20 CDS27104.1 - 1.5e-138 462.6 7.7 1.9e-138 462.3 7.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDS27104.1 - 2.7e-20 72.7 1.3 5.1e-20 71.8 1.3 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDS27104.1 - 1.1e-09 38.5 8.3 1.8e-07 31.3 0.2 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDS27104.1 - 0.00023 21.5 0.0 1.8 9.0 0.0 4.1 2 2 2 4 4 4 2 HEAT repeats Glyc_hyd_38C_2 PF18230.1 CDS27104.1 - 0.15 12.2 1.6 8.3 6.6 0.5 2.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal sub-domain DUF5578 PF17741.1 CDS27104.1 - 0.58 9.5 4.4 3.2 7.1 0.1 3.7 4 1 1 5 5 5 0 Family of unknown function (DUF5578) MARVEL PF01284.23 CDS27105.1 - 3.4e-15 56.3 19.3 4.9e-15 55.8 19.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Asn_synthase PF00733.21 CDS27106.1 - 2.5e-16 60.3 0.5 4.7e-08 33.1 0.3 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CDS27106.1 - 0.00025 21.0 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Peptidase_S9_N PF02897.15 CDS27107.1 - 8.3e-127 423.4 0.4 1.3e-126 422.8 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CDS27107.1 - 2.4e-63 213.4 0.0 5.3e-63 212.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 CDS27107.1 - 0.095 12.2 0.0 0.91 9.0 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase MFS_1 PF07690.16 CDS27108.1 - 2.6e-40 138.4 29.8 2.6e-40 138.4 29.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2721 PF11026.8 CDS27108.1 - 7.7 6.4 12.3 0.084 12.8 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RNA_pol_Rpb8 PF03870.15 CDS27112.1 - 2.5e-49 167.1 0.5 2.8e-49 166.9 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CDS27112.1 - 2.4e-05 24.4 0.4 0.0022 18.1 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Mak10 PF04112.13 CDS27114.1 - 4.8e-18 65.2 0.1 5.5e-17 61.8 0.1 2.6 1 1 1 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cadherin PF00028.17 CDS27115.1 - 2.2e-71 236.3 2.1 7.2e-21 74.4 0.1 7.7 7 0 0 7 7 7 7 Cadherin domain Cadherin_3 PF16184.5 CDS27115.1 - 4.5e-07 29.9 5.1 1.6 8.7 0.0 6.3 7 0 0 7 7 7 3 Cadherin-like Cadherin_2 PF08266.12 CDS27115.1 - 0.00015 21.5 0.0 0.31 10.9 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like RET_CLD1 PF17756.1 CDS27115.1 - 0.0041 17.4 0.0 1.2 9.4 0.0 3.4 4 0 0 4 4 4 1 RET Cadherin like domain 1 COesterase PF00135.28 CDS27116.1 - 9.3e-62 209.5 0.0 2e-61 208.4 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS27116.1 - 0.039 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thymidylate_kin PF02223.17 CDS27116.1 - 0.16 11.6 0.0 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase Gcd10p PF04189.13 CDS27117.1 - 2.5e-49 168.0 0.3 3.7e-49 167.5 0.3 1.4 1 0 0 1 1 1 1 Gcd10p family HTH_48 PF17906.1 CDS27118.1 - 1.9e-09 37.4 0.1 3.2e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Transposase_1 PF01359.18 CDS27118.1 - 0.0098 15.7 0.0 0.038 13.8 0.0 2.0 1 1 0 1 1 1 1 Transposase (partial DDE domain) Ig_5 PF16681.5 CDS27119.1 - 0.0035 17.7 0.6 0.1 13.0 0.0 3.0 2 1 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain EphA2_TM PF14575.6 CDS27119.1 - 0.016 16.1 0.1 0.04 14.8 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ig_3 PF13927.6 CDS27119.1 - 0.017 15.7 2.4 0.035 14.7 0.1 2.6 2 1 0 2 2 2 0 Immunoglobulin domain I-set PF07679.16 CDS27119.1 - 0.023 14.8 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS27119.1 - 0.031 14.6 0.1 0.031 14.6 0.1 2.5 3 1 0 3 3 3 0 Immunoglobulin domain MAP17 PF15807.5 CDS27119.1 - 0.038 14.2 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Calx-beta PF03160.14 CDS27121.2 - 1.2e-58 195.5 13.8 1.9e-27 95.4 1.6 4.0 4 0 0 4 4 4 3 Calx-beta domain Na_Ca_ex_C PF16494.5 CDS27121.2 - 1.5e-28 99.8 1.0 2.8e-28 98.9 1.0 1.4 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain Na_Ca_ex PF01699.24 CDS27121.2 - 2.2e-28 99.1 14.9 3.7e-28 98.4 14.9 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein ABC2_membrane PF01061.24 CDS27121.2 - 1.2 8.5 11.4 0.14 11.6 6.1 2.1 2 0 0 2 2 2 0 ABC-2 type transporter DHHC PF01529.20 CDS27121.2 - 6.2 6.9 7.2 38 4.4 0.1 2.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase GED PF02212.18 CDS27123.1 - 1.2e-18 67.0 3.4 1.9e-18 66.4 3.4 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF816 PF05674.12 CDS27123.1 - 0.011 15.6 1.4 0.016 15.1 1.4 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Kelch_1 PF01344.25 CDS27127.1 - 2.1e-17 62.4 0.1 1.3e-08 34.3 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CDS27127.1 - 7.1e-13 48.3 0.1 1.8e-06 28.0 0.0 3.4 2 1 1 3 3 3 2 Kelch motif BTB PF00651.31 CDS27127.1 - 6.2e-12 45.7 0.0 1.6e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDS27127.1 - 1e-07 32.0 0.3 0.00012 22.2 0.3 2.6 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDS27127.1 - 1.2e-07 31.4 0.0 0.00071 19.5 0.0 4.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CDS27127.1 - 7.8e-06 26.0 0.0 2.9e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS27127.1 - 0.00018 21.5 0.1 0.0033 17.4 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS27127.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 2.7 4 0 0 4 4 4 1 Kelch motif SH3_10 PF17902.1 CDS27127.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Cpn60_TCP1 PF00118.24 CDS27128.2 - 0.0016 17.1 0.2 0.0018 17.0 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF313 PF03754.13 CDS27128.2 - 0.0059 16.8 0.5 0.0085 16.3 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF313) HisK_sensor PF18698.1 CDS27128.2 - 0.025 15.0 0.5 0.035 14.5 0.5 1.2 1 0 0 1 1 1 0 Histidine kinase sensor domain EspB_PE PF18625.1 CDS27128.2 - 0.058 13.8 0.1 0.094 13.2 0.1 1.3 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain T4bSS_IcmS PF12608.8 CDS27130.1 - 0.025 14.9 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment Y_phosphatase PF00102.27 CDS27136.1 - 3.6e-06 26.7 0.1 4.2e-06 26.5 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NADH-u_ox-rdase PF10785.9 CDS27136.1 - 0.088 13.5 0.0 0.11 13.2 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Flt3_lig PF02947.14 CDS27137.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 flt3 ligand Ank_2 PF12796.7 CDS27139.1 - 7.8e-23 80.9 0.0 2.1e-08 34.6 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27139.1 - 1e-19 70.6 0.1 1.1e-06 29.0 0.0 6.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS27139.1 - 6.8e-19 67.7 0.2 8.9e-08 32.3 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS27139.1 - 1.7e-16 58.6 0.0 0.00015 21.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat PDZ_6 PF17820.1 CDS27139.1 - 2e-11 43.5 0.0 4.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank PF00023.30 CDS27139.1 - 4.8e-10 39.4 2.0 0.00063 20.1 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat PDZ PF00595.24 CDS27139.1 - 7.1e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS27139.1 - 9.1e-06 25.9 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ZapB PF06005.12 CDS27140.1 - 0.0021 18.5 7.3 2.9 8.4 8.7 2.7 2 1 0 2 2 2 1 Cell division protein ZapB Spc7 PF08317.11 CDS27140.1 - 0.019 13.9 2.7 0.03 13.2 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.11 CDS27140.1 - 0.03 13.9 0.4 0.044 13.4 0.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1192 PF06698.11 CDS27140.1 - 0.06 13.4 0.2 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FapA PF03961.13 CDS27140.1 - 0.29 9.7 0.6 0.41 9.2 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 CDS27140.1 - 0.41 11.2 8.0 1.8 9.1 8.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 CDS27140.1 - 0.5 9.6 7.7 0.56 9.5 6.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 CDS27140.1 - 1.8 9.5 10.4 9 7.3 6.8 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 CDS27140.1 - 2.2 8.1 12.3 1.1 9.0 1.7 2.9 2 1 1 3 3 3 0 Septum formation initiator NDUF_B4 PF07225.12 CDS27141.1 - 1e-14 54.5 0.0 1.2e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Arrestin_C PF02752.22 CDS27142.1 - 2.1e-10 41.2 0.0 5.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain TAF8_C PF10406.9 CDS27143.1 - 6.1e-13 49.1 0.7 1.1e-12 48.2 0.7 1.4 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CDS27143.1 - 7.3e-11 41.9 0.1 1.2e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CDS27143.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Rpr2 PF04032.16 CDS27144.1 - 7.7e-07 29.3 9.5 1.3e-06 28.6 9.5 1.4 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_7 PF02591.15 CDS27144.1 - 1.5e-06 28.3 1.0 1.5e-06 28.3 1.0 1.9 2 0 0 2 2 2 1 C4-type zinc ribbon domain DZR PF12773.7 CDS27144.1 - 0.22 11.5 3.6 9.9 6.3 3.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon DUF4674 PF15719.5 CDS27144.1 - 0.43 10.6 4.5 13 5.7 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) HypA PF01155.19 CDS27144.1 - 0.87 9.6 5.1 12 6.0 5.0 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADD_ATRX PF17981.1 CDS27144.1 - 1.3 8.9 9.8 0.43 10.5 1.8 2.5 1 1 1 2 2 2 0 Cysteine Rich ADD domain Ribosomal_L37e PF01907.19 CDS27144.1 - 1.5 9.1 5.8 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L37e Trm112p PF03966.16 CDS27145.1 - 1.5e-07 31.9 0.1 2.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein JAB PF01398.21 CDS27146.1 - 1.3e-31 109.0 0.0 2.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDS27146.1 - 7e-29 100.5 1.7 7e-29 100.5 1.7 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function 7tm_1 PF00001.21 CDS27147.1 - 4e-17 62.4 14.8 4e-17 62.4 14.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS27147.1 - 1.1e-05 24.9 21.8 0.00065 19.1 2.5 2.7 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDS27147.1 - 0.35 10.5 26.6 0.024 14.3 17.5 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx NepR PF18557.1 CDS27148.1 - 0.24 11.1 0.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma factor NepR zf-AN1 PF01428.16 CDS27149.1 - 0.00048 20.2 9.2 0.00048 20.2 9.2 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger IBR PF01485.21 CDS27149.1 - 0.00073 19.7 4.5 0.00073 19.7 4.5 2.9 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain R3H PF01424.22 CDS27149.1 - 0.0053 16.7 0.1 0.13 12.3 0.0 2.9 2 0 0 2 2 2 1 R3H domain 7TM_GPCR_Srw PF10324.9 CDS27150.1 - 0.00025 20.4 21.1 0.042 13.1 0.6 3.0 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw Abhydrolase_9_N PF15420.6 CDS27150.1 - 1.6 8.7 3.8 1.2 9.1 0.1 2.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus TPR_12 PF13424.6 CDS27151.1 - 4.5e-08 33.3 9.7 9.1e-06 25.9 2.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS27151.1 - 0.0076 16.4 14.5 0.019 15.2 0.5 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27151.1 - 0.028 14.5 15.1 0.99 9.7 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS27151.1 - 0.054 13.3 10.0 2.4 8.1 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS27151.1 - 0.54 10.4 4.2 39 4.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDS27151.1 - 4.2 7.9 12.0 0.13 12.7 1.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB PF00651.31 CDS27154.1 - 2.1e-12 47.2 0.0 4.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain JmjC PF02373.22 CDS27155.1 - 9.2e-18 64.7 0.7 4.7e-17 62.5 0.7 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDS27155.1 - 3.1e-14 53.3 0.1 7.2e-14 52.1 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain Pkinase PF00069.25 CDS27156.1 - 1.3e-57 195.2 0.0 2.3e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27156.1 - 6.5e-29 101.0 0.5 1.1e-28 100.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDS27156.1 - 0.054 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 CDS27157.1 - 0.00027 20.6 6.8 0.00038 20.1 6.8 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 CTV_P6 PF06706.11 CDS27157.1 - 0.003 17.2 1.6 0.0044 16.7 1.6 1.2 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein Protocadherin PF08374.11 CDS27157.1 - 0.0035 17.4 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 Protocadherin MLANA PF14991.6 CDS27157.1 - 0.0042 17.4 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein melan-A SKG6 PF08693.10 CDS27157.1 - 0.0047 16.3 0.6 0.0067 15.8 0.6 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 CDS27157.1 - 0.0051 16.3 0.1 0.0059 16.1 0.1 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 CDS27157.1 - 0.0051 16.7 0.0 0.0056 16.6 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.6 CDS27157.1 - 0.0084 16.4 0.0 0.0084 16.4 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 CDS27157.1 - 0.01 16.1 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 CDS27157.1 - 0.011 16.6 0.0 0.013 16.4 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ferric_reduct PF01794.19 CDS27157.1 - 0.015 15.4 0.3 0.018 15.1 0.3 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Mid2 PF04478.12 CDS27157.1 - 0.016 15.0 2.9 0.021 14.7 2.9 1.3 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Cadherin_C_2 PF16492.5 CDS27157.1 - 0.017 15.9 0.0 0.023 15.4 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Tweety PF04906.13 CDS27157.1 - 0.026 13.2 0.1 0.028 13.1 0.1 1.1 1 0 0 1 1 1 0 Tweety ABC2_membrane_2 PF12679.7 CDS27157.1 - 0.027 13.7 0.5 0.032 13.5 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Syndecan PF01034.20 CDS27157.1 - 0.028 14.3 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 CDS27157.1 - 0.079 13.4 0.4 0.096 13.1 0.4 1.1 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MtrB PF05440.12 CDS27157.1 - 0.096 13.1 0.2 0.14 12.6 0.2 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Stevor PF17410.2 CDS27157.1 - 0.12 11.9 0.4 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 CDS27157.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2207 PF09972.9 CDS27157.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NCU-G1 PF15065.6 CDS27157.1 - 0.19 10.7 2.0 0.24 10.3 2.0 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 LRRC37AB_C PF14914.6 CDS27157.1 - 0.19 11.6 0.4 0.25 11.3 0.4 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MtrF PF09472.10 CDS27157.1 - 0.23 10.9 3.7 0.35 10.3 3.7 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TSP_1 PF00090.19 CDS27158.1 - 0.0002 21.5 7.1 0.0002 21.5 7.1 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain Methyltr_RsmB-F PF01189.17 CDS27159.1 - 4e-76 255.1 0.0 6.3e-76 254.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CDS27159.1 - 4.9e-07 30.2 0.0 1.3e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CDS27159.1 - 7.4e-07 29.4 0.1 1.4e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDS27159.1 - 0.0039 17.0 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 CDS27159.1 - 0.035 14.4 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) PCMT PF01135.19 CDS27159.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDS27159.1 - 0.09 13.5 0.1 0.22 12.3 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain R3H-assoc PF13902.6 CDS27159.1 - 0.098 13.0 0.3 0.098 13.0 0.3 1.9 2 0 0 2 2 2 0 R3H-associated N-terminal domain zf-UBR PF02207.20 CDS27160.1 - 7.7e-12 45.2 12.9 7.7e-12 45.2 12.9 3.2 3 1 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) Lysyl_oxidase PF01186.17 CDS27161.1 - 3.8e-74 248.8 2.5 3.8e-74 248.8 2.5 1.7 2 0 0 2 2 2 1 Lysyl oxidase SRCR PF00530.18 CDS27161.1 - 7.9e-36 122.6 7.6 1.5e-26 92.8 0.8 2.9 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CDS27161.1 - 3.5e-06 27.5 1.7 0.00077 20.0 0.5 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CDS27161.1 - 0.0077 16.7 0.6 6.3 7.4 0.1 2.8 2 0 0 2 2 2 2 Hepsin, SRCR domain Ribosomal_L5e PF17144.4 CDS27162.1 - 2.8e-85 284.3 0.8 2.8e-85 284.3 0.8 1.6 2 0 0 2 2 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDS27162.1 - 2.4e-34 118.1 12.2 5.1e-34 117.1 12.2 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Hydrolase_4 PF12146.8 CDS27162.1 - 3.8e-17 62.3 0.1 1.1e-12 47.7 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDS27162.1 - 5.3e-07 29.6 0.8 0.0003 20.5 0.5 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDS27162.1 - 9.3e-06 26.4 0.3 1.7e-05 25.5 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDS27162.1 - 2.6e-05 23.8 0.0 9.5e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CDS27162.1 - 0.00037 20.4 0.1 0.00096 19.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDS27162.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDS27162.1 - 0.0095 15.6 0.1 0.13 11.9 0.1 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 CDS27162.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 CDS27162.1 - 0.18 11.4 0.1 2.6 7.6 0.0 2.4 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Atg14 PF10186.9 CDS27162.1 - 0.84 8.7 3.0 1.3 8.1 3.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_C15 PF01470.17 CDS27163.1 - 3e-13 50.4 0.0 1e-12 48.7 0.0 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase Forkhead PF00250.18 CDS27164.1 - 7.2e-35 119.1 0.1 1.5e-34 118.1 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain zf-C2H2 PF00096.26 CDS27165.1 - 6.9e-33 111.3 55.3 0.0002 21.6 1.9 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS27165.1 - 3.9e-28 95.7 55.9 0.00012 22.6 3.8 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS27165.1 - 7.1e-28 95.8 53.2 9.5e-06 25.8 1.9 9.0 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS27165.1 - 1.3e-15 57.2 41.5 0.025 14.9 0.1 8.4 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS27165.1 - 5.2e-14 52.1 34.2 0.03 14.7 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CDS27165.1 - 9.9e-07 29.5 29.3 0.072 13.8 1.4 6.3 1 1 5 6 6 6 5 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CDS27165.1 - 2.1e-05 24.2 39.9 0.0016 18.2 0.1 8.1 8 0 0 8 8 8 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 CDS27165.1 - 0.0066 16.7 34.1 0.099 13.0 3.1 4.7 1 1 4 5 5 5 3 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 CDS27165.1 - 0.0085 16.2 40.0 0.7 10.1 3.3 7.1 4 2 4 8 8 8 2 Zinc ribbon domain zf-C2H2_2 PF12756.7 CDS27165.1 - 0.033 14.5 37.7 0.97 9.8 0.2 7.3 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zinc-ribbons_6 PF07191.12 CDS27165.1 - 0.051 13.5 25.7 21 5.2 6.0 6.3 1 1 3 4 4 4 0 zinc-ribbons zinc_ribbon_5 PF13719.6 CDS27165.1 - 0.31 10.9 0.1 0.31 10.9 0.1 6.6 8 0 0 8 8 8 0 zinc-ribbon domain HypA PF01155.19 CDS27165.1 - 0.35 10.9 24.3 18 5.4 2.7 4.6 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Desulfoferrod_N PF06397.12 CDS27165.1 - 0.37 10.4 31.6 2.4 7.9 0.1 7.2 8 0 0 8 8 8 0 Desulfoferrodoxin, N-terminal domain zf-C2HC_2 PF13913.6 CDS27165.1 - 0.48 10.4 0.1 0.48 10.4 0.1 7.8 8 0 0 8 8 8 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 CDS27165.1 - 1.7 8.3 30.3 2.5 7.8 0.0 7.8 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 CDS27165.1 - 6.1 5.3 37.5 0.52 8.8 2.1 5.8 1 1 4 6 6 6 0 Protein of unknown function (DUF629) zf-AN1 PF01428.16 CDS27165.1 - 7.1 6.9 47.0 3.5 7.8 0.2 8.2 6 1 2 8 8 8 0 AN1-like Zinc finger MH1 PF03165.16 CDS27166.1 - 3.8e-32 110.6 0.1 9.2e-32 109.3 0.1 1.7 1 0 0 1 1 1 1 MH1 domain MH2 PF03166.14 CDS27166.1 - 2.3e-18 67.1 0.5 4.2e-18 66.2 0.0 1.6 2 0 0 2 2 2 1 MH2 domain DUF1955 PF09205.10 CDS27166.1 - 0.026 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) DUF3385 PF11865.8 CDS27166.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) MH2 PF03166.14 CDS27167.1 - 2.5e-23 83.3 0.0 3.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain SF3b10 PF07189.11 CDS27169.1 - 5.8e-40 135.3 0.0 6.4e-40 135.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ribosomal_S15 PF00312.22 CDS27170.1 - 0.0024 18.0 1.3 0.0024 18.0 1.3 2.2 2 1 0 2 2 2 1 Ribosomal protein S15 ETC_C1_NDUFA5 PF04716.14 CDS27170.1 - 0.0028 17.4 0.6 0.0079 16.0 0.1 2.0 2 0 0 2 2 2 1 ETC complex I subunit conserved region T5orf172 PF10544.9 CDS27170.1 - 0.087 13.4 1.8 0.098 13.2 0.3 1.8 2 0 0 2 2 2 0 T5orf172 domain Pro-NT_NN PF07421.11 CDS27170.1 - 0.56 10.4 5.3 0.9 9.8 5.3 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Integrase_H2C2 PF17921.1 CDS27171.2 - 6.9e-34 115.7 7.9 1.4e-16 60.3 1.2 3.0 3 0 0 3 3 3 2 Integrase zinc binding domain rve PF00665.26 CDS27171.2 - 6.2e-30 103.8 0.0 2.7e-22 79.2 0.0 3.8 3 0 0 3 3 3 2 Integrase core domain RT_RNaseH_2 PF17919.1 CDS27171.2 - 1.2e-27 95.9 0.3 4.5e-27 94.0 0.3 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS27171.2 - 3.5e-26 91.5 0.1 1.3e-25 89.7 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CDS27171.2 - 4.7e-10 39.5 0.6 0.00037 20.7 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger rve_3 PF13683.6 CDS27171.2 - 5.4e-10 38.9 0.0 0.00087 19.0 0.0 2.9 2 0 0 2 2 2 2 Integrase core domain BORCS7 PF16088.5 CDS27171.2 - 0.063 13.5 0.4 0.2 11.9 0.4 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Zn_Tnp_IS1 PF03811.13 CDS27171.2 - 0.46 10.2 3.4 12 5.7 0.2 2.5 2 0 0 2 2 2 0 InsA N-terminal domain DUF3074 PF11274.8 CDS27172.1 - 0.041 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Synaptobrevin PF00957.21 CDS27173.2 - 6.6e-29 99.6 2.5 8.4e-29 99.2 2.5 1.1 1 0 0 1 1 1 1 Synaptobrevin Collectrin PF16959.5 CDS27173.2 - 0.034 13.9 2.8 0.076 12.8 2.8 1.6 1 1 0 1 1 1 0 Renal amino acid transporter DUF2721 PF11026.8 CDS27173.2 - 0.15 11.9 0.2 0.15 11.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MFS_1 PF07690.16 CDS27175.1 - 2.1e-07 30.2 4.1 2.4e-07 30.0 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS27175.1 - 2e-06 26.9 7.1 2.4e-06 26.7 7.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter RhoGAP PF00620.27 CDS27177.2 - 1e-36 126.1 0.0 1.7e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 CDS27177.2 - 0.0013 19.0 0.0 0.0035 17.6 0.0 1.7 2 0 0 2 2 2 1 C2 domain Phage-tail_3 PF13550.6 CDS27177.2 - 0.039 13.8 0.2 0.08 12.8 0.2 1.4 1 0 0 1 1 1 0 Putative phage tail protein EAP30 PF04157.16 CDS27178.1 - 2.2e-69 233.4 0.2 2.4e-69 233.2 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PurA PF04845.13 CDS27179.1 - 1.5e-05 24.4 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein Transcrip_reg PF01709.20 CDS27180.1 - 1.9e-50 171.5 0.2 2.2e-50 171.3 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF2353 PF09789.9 CDS27181.1 - 0.0016 17.9 12.4 0.0016 17.9 12.4 3.6 4 0 0 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) TetR_C_23 PF17931.1 CDS27181.1 - 0.75 9.9 10.9 0.09 12.9 1.5 3.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Alanine_zipper PF11839.8 CDS27181.1 - 0.79 10.1 9.3 1.7 9.0 3.5 3.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein HSBP1 PF06825.12 CDS27181.1 - 2.8 7.9 8.5 24 4.9 0.1 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Ago_N_1 PF18351.1 CDS27181.1 - 3.1 8.3 10.3 0.39 11.2 0.3 3.4 3 1 1 4 4 4 0 Fungal Argonaute N-terminal domain DUF5082 PF16888.5 CDS27181.1 - 5.5 7.3 38.2 0.34 11.2 9.7 4.8 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) Adap_comp_sub PF00928.21 CDS27182.1 - 2.4e-76 256.6 0.0 2.9e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDS27182.1 - 6.4e-08 32.6 0.4 1.1e-07 31.9 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CDS27182.1 - 0.0011 18.4 0.0 0.0043 16.5 0.0 1.9 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FAD_binding_4 PF01565.23 CDS27183.1 - 3.5e-28 98.1 0.0 6.6e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 CDS27183.1 - 5.8e-17 62.2 0.1 7.6e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 FAD linked oxidases, C-terminal domain AAA PF00004.29 CDS27184.1 - 1.5e-43 148.4 0.0 2.7e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS27184.1 - 8.7e-11 41.5 0.1 2.4e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDS27184.1 - 9.9e-09 35.0 0.6 1.9e-08 34.1 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CDS27184.1 - 8.5e-08 32.8 0.2 6.3e-05 23.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDS27184.1 - 8.7e-06 26.1 0.1 0.0014 18.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CDS27184.1 - 1.6e-05 25.1 0.0 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDS27184.1 - 1.9e-05 24.5 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDS27184.1 - 2.1e-05 24.6 0.2 0.00074 19.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDS27184.1 - 0.00034 21.2 0.2 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CDS27184.1 - 0.0007 19.8 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CDS27184.1 - 0.0033 16.6 0.0 0.0092 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDS27184.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDS27184.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CDS27184.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDS27184.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 CDS27184.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 CDS27184.1 - 0.014 15.0 0.3 0.054 13.2 0.1 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 CDS27184.1 - 0.015 15.1 1.7 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CDS27184.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDS27184.1 - 0.021 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CDS27184.1 - 0.024 13.9 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CDS27184.1 - 0.041 13.6 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDS27184.1 - 0.042 13.8 0.7 0.95 9.3 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CDS27184.1 - 0.081 13.2 0.1 0.2 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 CDS27184.1 - 0.083 12.6 0.4 5.2 6.7 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase NACHT PF05729.12 CDS27184.1 - 0.093 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CDS27184.1 - 0.096 12.2 0.4 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CDS27184.1 - 0.1 11.9 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 CDS27184.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 CDS27184.1 - 0.86 10.1 4.4 99 3.3 5.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CDS27184.1 - 0.89 8.1 3.9 13 4.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain tRNA-synt_2c PF01411.19 CDS27185.1 - 2e-92 310.5 0.1 2.3e-71 241.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDS27185.1 - 3.1e-06 27.2 0.2 7.3e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Med29 PF11568.8 CDS27185.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Mediator complex subunit 29 QVR PF17064.5 CDS27186.1 - 0.079 13.2 1.9 0.24 11.7 1.9 1.8 1 1 0 1 1 1 0 Sleepless protein Zip PF02535.22 CDS27187.1 - 3.1e-35 122.0 21.3 1.5e-26 93.4 11.6 3.0 3 0 0 3 3 3 3 ZIP Zinc transporter TatC PF00902.18 CDS27187.1 - 0.23 11.2 7.9 0.92 9.3 7.9 2.2 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) PH_TFIIH PF08567.11 CDS27188.1 - 3.1e-19 69.1 0.1 6.3e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 CDS27188.1 - 1.8e-16 59.9 0.2 3e-12 46.3 0.1 2.8 2 0 0 2 2 2 2 BSD domain Ank_2 PF12796.7 CDS27189.2 - 5e-29 100.7 1.4 9.3e-15 55.0 0.8 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27189.2 - 2.7e-27 94.8 5.8 4.3e-09 36.7 0.3 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS27189.2 - 5.1e-26 90.4 10.5 8.3e-10 38.7 0.1 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS27189.2 - 1.7e-22 78.8 11.2 2.2e-05 24.7 0.9 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CDS27189.2 - 3.8e-20 69.8 7.9 0.00013 22.1 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat RabGAP-TBC PF00566.18 CDS27190.1 - 3.6e-21 75.8 0.4 3.6e-21 75.8 0.4 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain VCBS PF13517.6 CDS27191.1 - 1.5e-14 54.3 5.4 1e-06 29.2 0.4 4.3 3 2 3 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDS27191.1 - 1.2e-05 25.3 11.6 0.00064 19.8 0.8 4.8 5 0 0 5 5 5 2 FG-GAP repeat Ninjurin PF04923.12 CDS27191.1 - 0.019 14.9 0.3 0.039 13.9 0.3 1.4 1 0 0 1 1 1 0 Ninjurin Mito_morph_reg PF14972.6 CDS27193.1 - 1.2e-40 138.8 0.0 7.1e-33 113.5 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial morphogenesis regulator Spc7_N PF15402.6 CDS27193.1 - 0.22 9.7 0.5 0.28 9.4 0.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Sushi PF00084.20 CDS27196.1 - 5e-42 142.3 54.4 3.9e-10 40.2 0.3 10.8 10 1 0 10 10 10 9 Sushi repeat (SCR repeat) cEGF PF12662.7 CDS27196.1 - 0.095 12.7 16.1 16 5.5 0.2 6.8 6 0 0 6 6 6 0 Complement Clr-like EGF-like Cyclin_N PF00134.23 CDS27197.2 - 2.6e-11 43.3 0.6 1.2e-07 31.5 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 CDS27197.2 - 0.0022 18.0 0.7 0.99 9.5 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 CDS27197.2 - 0.0049 16.9 0.2 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 Cyclin, C-terminal domain Pribosyltran_N PF13793.6 CDS27197.2 - 0.1 12.6 1.0 12 5.8 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Cyclin_C_2 PF16899.5 CDS27197.2 - 0.11 12.9 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB_C_1 PF18542.1 CDS27197.2 - 0.53 10.3 3.6 7 6.7 0.1 3.2 2 1 1 3 3 3 0 Transcription factor IIB C-terminal module 1 RRM_3 PF08777.11 CDS27198.1 - 5.1e-10 39.3 0.2 5.1e-10 39.3 0.2 2.6 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 CDS27198.1 - 5.9e-07 29.2 0.1 1.4e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 CDS27198.1 - 0.039 14.0 0.2 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 La domain DUF1574 PF07611.11 CDS27198.1 - 0.046 13.0 0.3 0.055 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Nup35_RRM_2 PF14605.6 CDS27198.1 - 0.098 12.7 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif YebO PF13974.6 CDS27198.1 - 0.25 11.4 2.4 0.66 10.1 0.8 2.3 2 0 0 2 2 2 0 YebO-like protein Band_3_cyto PF07565.13 CDS27200.1 - 4.1e-13 49.8 0.0 6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain HCO3_cotransp PF00955.21 CDS27200.1 - 6.8e-07 28.5 0.0 9.6e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 HCO3- transporter family PatG_C PF18065.1 CDS27200.1 - 0.087 12.8 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 PatG C-terminal DC_STAMP PF07782.13 CDS27201.1 - 1.3e-43 149.1 0.0 4.6e-43 147.3 0.0 2.0 1 0 0 1 1 1 1 DC-STAMP-like protein MIT_LIKE_ACTX PF17556.2 CDS27201.1 - 0.048 14.3 1.0 5.2 7.7 0.1 2.7 1 1 1 2 2 2 0 MIT-like atracotoxin family Peptidase_C12 PF01088.21 CDS27201.1 - 0.11 12.2 0.9 0.36 10.5 0.9 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Complex1_LYR PF05347.15 CDS27202.1 - 1.1e-08 35.0 3.0 1.2e-07 31.6 3.0 2.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDS27202.1 - 0.0037 18.0 0.3 0.0072 17.0 0.3 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Nop52 PF05997.12 CDS27203.1 - 5.9e-30 104.7 0.3 1.1e-29 103.8 0.3 1.5 1 0 0 1 1 1 1 Nucleolar protein,Nop52 ETC_C1_NDUFA5 PF04716.14 CDS27203.1 - 0.11 12.3 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 ETC complex I subunit conserved region PARM PF17061.5 CDS27203.1 - 2.6 8.1 11.0 3.8 7.6 11.0 1.2 1 0 0 1 1 1 0 PARM EF-hand_6 PF13405.6 CDS27204.1 - 1.3e-09 37.2 1.3 0.00076 19.2 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDS27204.1 - 1.4e-09 36.8 4.6 5.4e-05 22.5 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDS27204.1 - 1.1e-07 32.2 3.2 0.0021 18.5 0.9 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDS27204.1 - 1.8e-05 25.0 0.1 0.053 13.8 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CDS27204.1 - 7.5e-05 22.0 4.6 0.045 13.3 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS27204.1 - 0.04 13.8 6.3 0.49 10.3 0.2 3.3 4 0 0 4 4 4 0 EF-hand domain pair ARID PF01388.21 CDS27205.1 - 1.2e-20 74.0 0.1 2.9e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DAO PF01266.24 CDS27206.1 - 7.9e-51 173.7 0.0 1.1e-50 173.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CDS27206.1 - 9e-38 129.0 0.0 1.6e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 CDS27206.1 - 3.8e-10 40.1 1.6 8.1e-10 39.0 1.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS27206.1 - 3.4e-07 29.3 1.8 0.0025 17.3 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS27206.1 - 1.4e-06 27.7 1.7 0.061 13.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain FAD_binding_2 PF00890.24 CDS27206.1 - 5.1e-05 22.5 1.5 0.0022 17.1 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain EF-hand_8 PF13833.6 CDS27206.1 - 6.1e-05 22.8 0.2 0.00041 20.1 0.6 2.2 2 0 0 2 2 2 1 EF-hand domain pair FAD_oxidored PF12831.7 CDS27206.1 - 7.9e-05 22.2 0.3 0.00016 21.2 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CDS27206.1 - 0.014 14.5 0.1 0.16 11.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CDS27206.1 - 0.046 12.9 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDS27206.1 - 0.054 12.5 0.1 5.6 5.9 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CDS27206.1 - 0.065 11.9 0.3 0.19 10.4 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein EF-hand_5 PF13202.6 CDS27206.1 - 0.084 12.4 6.0 0.49 10.0 0.9 2.5 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 CDS27206.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain FAD_binding_3 PF01494.19 CDS27206.1 - 0.13 11.5 0.1 0.61 9.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Mito_carr PF00153.27 CDS27207.1 - 1.6e-62 207.5 2.4 1.1e-22 79.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.17 CDS27208.1 - 0.8 10.0 9.3 0.071 13.4 3.7 2.2 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Exo_endo_phos_2 PF14529.6 CDS27209.1 - 7.1e-12 45.2 0.7 1.4e-11 44.3 0.7 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS27209.1 - 0.00012 21.7 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PI-PLC-X PF00388.19 CDS27210.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Homeodomain PF00046.29 CDS27211.2 - 7.7e-22 76.9 2.3 1.8e-21 75.7 2.3 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDS27211.2 - 0.00078 18.9 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CDS27211.2 - 0.0029 17.5 1.5 0.0058 16.5 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain APC_u9 PF16633.5 CDS27211.2 - 1.3 10.2 8.0 0.13 13.4 1.4 2.5 2 1 0 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions RhoGAP PF00620.27 CDS27212.1 - 2.9e-44 150.6 0.0 8.6e-44 149.0 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 CDS27212.1 - 4.1e-07 30.2 0.0 1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF745 PF05335.13 CDS27212.1 - 0.28 10.9 2.7 0.32 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Myotub-related PF06602.14 CDS27213.1 - 2.4e-133 444.5 0.0 3.3e-133 444.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.8 CDS27213.1 - 0.00057 19.6 0.1 0.0016 18.2 0.1 1.8 2 0 0 2 2 2 1 Myotubularin-associated protein Y_phosphatase PF00102.27 CDS27213.1 - 0.017 14.7 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CDS27213.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GRAM PF02893.20 CDS27213.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain ATP_bind_1 PF03029.17 CDS27214.1 - 8.9e-75 251.6 0.0 1.1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CDS27214.1 - 1.5e-06 27.9 0.0 2.4e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDS27214.1 - 0.00012 21.6 0.1 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 CDS27214.1 - 0.00042 20.1 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS27214.1 - 0.00048 20.7 0.0 0.0051 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDS27214.1 - 0.00058 19.9 0.0 0.0062 16.6 0.0 2.4 2 1 0 2 2 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CDS27214.1 - 0.0007 19.3 0.0 0.0073 16.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CDS27214.1 - 0.00088 19.7 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 CDS27214.1 - 0.00098 18.7 0.1 0.74 9.4 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.18 CDS27214.1 - 0.0026 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CDS27214.1 - 0.004 17.3 0.0 0.0069 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CDS27214.1 - 0.0073 16.2 0.1 0.017 15.1 0.0 1.6 2 0 0 2 2 1 1 NACHT domain CLP1_P PF16575.5 CDS27214.1 - 0.013 15.3 0.0 0.29 10.9 0.0 2.3 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 CDS27214.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 CDS27214.1 - 0.024 14.6 0.0 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 CDS27214.1 - 0.025 14.9 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CDS27214.1 - 0.025 14.7 0.7 0.12 12.5 0.3 2.1 3 0 0 3 3 3 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 CDS27214.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CDS27214.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 CDS27214.1 - 0.038 14.1 0.2 0.45 10.6 0.2 2.4 1 1 0 1 1 1 0 Dynamin family MobB PF03205.14 CDS27214.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CDS27214.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CDS27214.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS27214.1 - 0.083 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDS27214.1 - 0.11 12.5 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 CDS27214.1 - 0.13 11.2 0.0 0.35 9.7 0.0 1.6 2 0 0 2 2 2 0 YcjX-like family, DUF463 Arf PF00025.21 CDS27214.1 - 0.14 11.6 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 CDS27214.1 - 0.16 11.3 0.0 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.20 CDS27214.1 - 0.26 10.4 1.1 0.82 8.8 0.1 2.2 3 0 0 3 3 3 0 G-protein alpha subunit DUF2052 PF09747.9 CDS27215.1 - 1.7e-23 83.8 24.4 2.3e-14 54.0 14.2 2.4 2 1 1 3 3 3 2 Coiled-coil domain containing protein (DUF2052) EKAL PF17986.1 CDS27215.1 - 0.15 12.1 4.0 0.18 11.9 2.5 1.9 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain Syja_N PF02383.18 CDS27216.2 - 3.5e-112 374.8 0.0 6.4e-82 275.4 0.0 3.4 3 0 0 3 3 3 3 SacI homology domain zf-RING_2 PF13639.6 CDS27216.2 - 3.4e-05 24.1 6.6 0.00017 21.8 6.6 2.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDS27216.2 - 0.0011 18.6 1.4 0.0035 17.1 1.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CDS27216.2 - 0.0054 17.0 5.3 0.015 15.6 5.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDS27216.2 - 0.035 14.0 6.5 0.2 11.6 6.5 2.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS27216.2 - 0.069 13.0 6.5 0.2 11.5 6.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDS27216.2 - 0.13 12.3 2.8 0.32 11.1 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDS27216.2 - 0.37 10.4 5.2 1.1 8.9 5.2 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CDS27216.2 - 0.47 10.5 6.9 1.7 8.7 6.9 2.0 1 0 0 1 1 1 0 zinc-RING finger domain HET-S PF17108.5 CDS27216.2 - 1.9 8.3 5.2 85 3.0 0.1 3.4 3 0 0 3 3 3 0 N-terminal small S protein of HET, non-prionic Tetraspanin PF00335.20 CDS27217.1 - 5.7e-33 114.5 10.3 6.8e-33 114.3 10.3 1.0 1 0 0 1 1 1 1 Tetraspanin family Pox_A14 PF05767.12 CDS27217.1 - 1.1e-06 28.6 6.5 0.00032 20.8 1.2 2.3 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 SUR7 PF06687.12 CDS27217.1 - 0.0062 16.2 6.6 0.38 10.3 4.3 2.1 2 0 0 2 2 2 2 SUR7/PalI family Chordopox_A13L PF05961.11 CDS27217.1 - 0.033 14.4 0.1 0.033 14.4 0.1 3.0 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Abhydrolase_9_N PF15420.6 CDS27217.1 - 0.046 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1218 PF06749.12 CDS27217.1 - 0.064 13.8 2.6 0.45 11.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Sex_peptide PF08138.11 CDS27217.1 - 2.5 8.3 5.2 0.56 10.4 0.3 2.4 2 0 0 2 2 2 0 Sex peptide (SP) family U1snRNP70_N PF12220.8 CDS27218.1 - 2.1e-26 92.4 6.6 2.1e-26 92.4 6.6 2.5 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CDS27218.1 - 3.5e-22 78.0 0.1 5.8e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS27218.1 - 0.086 13.0 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RIIa PF02197.17 CDS27219.1 - 0.0051 16.4 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Ion_trans PF00520.31 CDS27221.1 - 3.6e-41 141.0 22.8 5e-41 140.5 22.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDS27221.1 - 2.5e-22 79.1 0.3 5e-22 78.1 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDS27221.1 - 5.4e-13 48.7 5.9 5.4e-13 48.7 5.9 2.1 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 CDS27221.1 - 0.0046 15.7 3.9 0.0046 15.7 3.9 2.0 1 1 1 2 2 2 1 Polycystin cation channel DUF2838 PF10998.8 CDS27223.1 - 2.9e-14 53.3 2.7 2.9e-14 53.3 2.7 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) Arrestin_N PF00339.29 CDS27225.1 - 2.2e-07 31.0 0.6 0.0063 16.6 0.2 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TMEM144 PF07857.12 CDS27226.2 - 9e-98 327.3 11.6 1.1e-97 327.0 11.6 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDS27226.2 - 1.1e-06 28.2 1.2 1.1e-06 28.2 1.2 2.7 2 2 0 2 2 2 1 Sugar transport protein CPP1-like PF11833.8 CDS27226.2 - 0.015 15.0 1.1 0.043 13.5 1.1 1.9 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DMT_YdcZ PF04657.13 CDS27226.2 - 2.8 8.2 23.3 0.026 14.8 9.5 3.3 2 2 0 3 3 3 0 Putative inner membrane exporter, YdcZ MH2 PF03166.14 CDS27227.1 - 2e-74 249.8 0.8 2.7e-74 249.4 0.8 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDS27227.1 - 1.9e-41 140.4 0.2 3.8e-41 139.5 0.2 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 CDS27227.1 - 0.0036 17.1 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 TMEM144 PF07857.12 CDS27228.1 - 2.5e-81 273.2 14.5 1.3e-79 267.6 14.5 2.0 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDS27228.1 - 6.7e-06 25.6 19.7 1.3e-05 24.7 0.5 3.0 3 0 0 3 3 3 2 Sugar transport protein DUF2759 PF10958.8 CDS27228.1 - 1.2 8.9 9.4 3.7 7.3 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) DUF4064 PF13273.6 CDS27228.1 - 3.9 7.8 0.0 0.51 10.6 3.6 3.9 5 1 0 5 5 5 0 Protein of unknown function (DUF4064) SelK_SelG PF10961.8 CDS27230.1 - 6.9e-11 42.6 0.0 7.4e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Selenoprotein SelK_SelG EF-hand_7 PF13499.6 CDS27231.2 - 4.7e-17 62.2 0.3 1.1e-14 54.6 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS27231.2 - 5.3e-16 56.9 0.2 1.8e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDS27231.2 - 4.6e-15 54.2 1.1 0.00086 19.0 0.1 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CDS27231.2 - 1.6e-14 53.5 0.1 2.2e-07 30.6 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS27231.2 - 1.2e-10 40.4 0.3 6.2e-06 25.5 0.0 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CDS27231.2 - 1.1e-06 28.9 0.1 0.088 13.1 0.0 2.9 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS27231.2 - 0.0024 17.8 0.1 0.015 15.2 0.0 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDS27231.2 - 0.023 14.6 0.7 6.7 6.6 0.0 3.4 2 1 2 4 4 4 0 Caleosin related protein zf-C2H2 PF00096.26 CDS27232.1 - 1.9e-11 43.8 30.9 0.0003 21.1 3.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS27232.1 - 3.9e-09 36.5 16.9 6e-06 26.4 2.9 5.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS27232.1 - 7.9e-05 22.8 11.6 0.4 11.0 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS27232.1 - 0.0053 16.7 21.9 0.015 15.3 3.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CDS27232.1 - 0.012 16.4 11.3 0.021 15.6 1.6 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 CDS27232.1 - 0.05 13.5 0.2 0.05 13.5 0.2 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 CDS27232.1 - 4.4 7.6 6.9 2.9 8.2 1.3 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 CDS27232.1 - 7.3 6.4 19.3 0.074 12.8 3.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 CDS27232.1 - 8.4 6.6 8.0 21 5.3 0.6 3.0 3 1 0 3 3 3 0 Zinc ribbon domain Tropomyosin_1 PF12718.7 CDS27233.1 - 0.018 15.2 1.8 0.063 13.4 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 CDS27233.1 - 7.9 6.8 8.1 7.5 6.9 1.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain DRMBL PF07522.14 CDS27234.1 - 3.2e-16 59.5 0.0 5.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CDS27234.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDS27234.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-rbx1 PF12678.7 CDS27235.1 - 5.8e-26 90.5 12.5 7.8e-26 90.1 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDS27235.1 - 2.3e-18 66.0 9.3 2.9e-18 65.7 9.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDS27235.1 - 5.3e-07 29.9 14.2 1.9e-05 24.9 14.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS27235.1 - 9.4e-06 25.4 3.2 9.4e-06 25.4 3.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS27235.1 - 0.00041 20.2 11.7 0.0032 17.3 11.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDS27235.1 - 0.0011 18.6 1.9 0.0011 18.6 1.9 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CDS27235.1 - 0.039 13.8 10.5 9.3 6.2 10.7 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS27235.1 - 0.046 13.7 6.3 0.1 12.6 6.3 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS27235.1 - 0.21 11.8 0.6 0.21 11.8 0.6 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CDS27235.1 - 0.25 11.0 14.3 31 4.3 14.3 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CDS27235.1 - 0.53 10.5 9.3 3.2 8.0 9.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 CDS27235.1 - 0.78 10.0 10.8 46 4.4 10.8 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 CDS27235.1 - 1.6 8.8 10.8 6.9 6.7 10.8 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 CDS27235.1 - 2.4 8.5 11.5 38 4.7 11.5 2.3 1 1 0 1 1 1 0 RING-like domain Ion_trans PF00520.31 CDS27236.2 - 5.2e-41 140.5 20.3 1.1e-40 139.4 20.3 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDS27236.2 - 1.5e-11 44.1 4.8 1.5e-11 44.1 4.8 1.9 2 0 0 2 2 2 1 Ion channel TauE PF01925.19 CDS27236.2 - 0.012 15.2 2.4 0.027 14.1 2.4 1.5 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PilP PF04351.13 CDS27236.2 - 0.13 12.2 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 Pilus assembly protein, PilP DUF3185 PF11381.8 CDS27236.2 - 0.21 11.6 3.1 0.57 10.2 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) DUF2614 PF11023.8 CDS27236.2 - 6.8 6.8 6.4 1.1e+02 2.9 4.8 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain PKD_channel PF08016.12 CDS27236.2 - 7.5 5.1 13.5 0.31 9.7 6.1 1.9 1 1 1 2 2 2 0 Polycystin cation channel DAGK_acc PF00609.19 CDS27237.1 - 8.5e-53 178.9 0.0 1.4e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 CDS27237.1 - 2e-25 88.4 51.0 1.4e-11 44.0 11.5 3.4 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 CDS27237.1 - 2.5e-23 82.0 0.0 5.1e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.23 CDS27237.1 - 1.1e-15 58.1 0.2 1.8e-07 31.7 0.1 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SMN PF06003.12 CDS27237.1 - 0.94 8.7 5.8 1.8 7.7 5.8 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) C1_2 PF03107.16 CDS27237.1 - 7.9 6.9 33.8 2.4 8.6 7.9 3.8 3 0 0 3 3 3 0 C1 domain Metallophos PF00149.28 CDS27238.2 - 1.9e-36 126.5 0.2 2.7e-36 126.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDS27238.2 - 0.00057 20.3 0.4 0.0017 18.7 0.4 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Y_phosphatase PF00102.27 CDS27239.2 - 1.8e-65 220.8 0.1 3.1e-32 112.0 0.2 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 CDS27239.2 - 1.1e-21 77.2 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDS27239.2 - 6.3e-05 23.2 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDS27239.2 - 0.015 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Y_phosphatase3 PF13350.6 CDS27239.2 - 0.023 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 CDS27239.2 - 0.032 14.0 0.1 0.095 12.5 0.1 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain E1-E2_ATPase PF00122.20 CDS27241.2 - 6.4e-53 179.0 0.2 6.4e-53 179.0 0.2 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDS27241.2 - 1.9e-46 158.1 4.9 1.9e-46 158.1 4.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDS27241.2 - 3.9e-22 78.1 0.0 7.6e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDS27241.2 - 1.5e-19 71.1 0.2 8e-19 68.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDS27241.2 - 2.6e-19 68.7 0.8 1.4e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDS27241.2 - 3.1e-06 27.1 1.8 8.3e-06 25.7 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDS27241.2 - 2.1e-05 25.0 0.1 6.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_His PF13393.6 CDS27242.2 - 4.4e-37 128.0 0.0 4.1e-32 111.7 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDS27242.2 - 2.5e-14 53.2 0.1 6.7e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CDS27242.2 - 4.7e-05 23.0 0.2 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 CDS27242.2 - 0.00047 20.2 0.1 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CDS27242.2 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 CDS27242.2 - 0.028 13.5 0.1 0.16 11.0 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) Arm PF00514.23 CDS27243.2 - 2.5e-27 94.0 21.1 6.5e-08 32.4 0.2 9.5 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CDS27243.2 - 4.2e-06 25.6 10.4 1.7e-05 23.6 2.3 3.0 3 0 0 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.13 CDS27243.2 - 3.2e-05 23.5 5.9 0.0011 18.5 0.2 3.3 3 0 0 3 3 3 1 Armadillo-like KAP PF05804.12 CDS27243.2 - 0.00027 19.2 5.2 0.012 13.8 4.6 2.7 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) DUF3361 PF11841.8 CDS27243.2 - 0.00062 19.7 2.6 0.11 12.4 0.1 3.4 2 1 0 3 3 3 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 CDS27243.2 - 0.017 15.1 0.6 1 9.4 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 CDS27243.2 - 0.036 14.6 3.7 30 5.3 0.7 4.7 4 1 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 CDS27243.2 - 0.056 13.7 6.4 13 6.3 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat V-ATPase_H_N PF03224.14 CDS27243.2 - 0.82 8.9 5.5 16 4.7 3.6 3.1 2 1 0 2 2 2 0 V-ATPase subunit H WD40 PF00400.32 CDS27244.2 - 1.2e-19 70.3 6.5 1.6e-05 25.5 0.2 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27244.2 - 9.7e-10 38.6 0.0 0.00065 19.9 0.0 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS27244.2 - 0.00045 20.1 0.0 0.0066 16.4 0.0 2.8 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A YabA PF06156.13 CDS27244.2 - 0.008 16.8 0.9 0.019 15.6 0.9 1.7 1 0 0 1 1 1 1 Initiation control protein YabA Ge1_WD40 PF16529.5 CDS27244.2 - 0.16 10.9 0.3 7 5.5 0.0 2.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NAC PF01849.18 CDS27246.2 - 6e-22 77.4 0.4 4e-21 74.7 0.2 2.4 2 0 0 2 2 2 1 NAC domain DMA PF03474.14 CDS27249.2 - 5.8e-05 22.6 0.0 0.6 9.8 0.0 3.3 3 0 0 3 3 3 2 DMRTA motif CUE PF02845.16 CDS27249.2 - 0.00018 21.2 0.0 1.3 8.8 0.0 3.6 3 0 0 3 3 3 3 CUE domain Smr PF01713.21 CDS27249.2 - 0.055 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Smr domain UPF0121 PF03661.13 CDS27250.1 - 3.9e-89 298.2 11.5 5.9e-89 297.6 11.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-C2H2_4 PF13894.6 CDS27250.1 - 3.1e-06 27.5 9.8 0.015 16.1 0.4 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS27250.1 - 0.001 19.4 15.3 0.01 16.3 0.3 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDS27250.1 - 0.0012 19.1 7.8 0.11 12.8 1.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS27250.1 - 0.015 15.7 3.2 5.1 7.6 1.2 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDS27250.1 - 0.028 14.4 8.1 0.6 10.2 0.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4395 PF14340.6 CDS27250.1 - 0.54 10.6 5.9 0.39 11.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) zf-C2H2_2 PF12756.7 CDS27250.1 - 2.1 8.7 11.7 4.9 7.6 0.6 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CDS27250.1 - 5.2 7.7 13.9 0.35 11.4 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger double domain Ras PF00071.22 CDS27251.1 - 3.3e-53 179.6 0.0 4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS27251.1 - 5.6e-30 104.0 0.0 8e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS27251.1 - 1.7e-15 56.9 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS27251.1 - 9.1e-05 22.1 0.2 0.00074 19.1 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS27251.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDS27251.1 - 0.00056 19.3 0.0 0.00073 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS27251.1 - 0.0041 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TetR_C_16 PF17920.1 CDS27251.1 - 0.0042 17.3 0.0 0.063 13.5 0.0 2.4 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain AAA_28 PF13521.6 CDS27251.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CDS27251.1 - 0.19 11.1 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Rad1 PF02144.16 CDS27252.1 - 1.5e-29 102.9 0.0 1.7e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SGS PF05002.15 CDS27253.1 - 2.2e-33 114.2 0.7 3.4e-33 113.6 0.7 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CDS27253.1 - 2.2e-12 47.8 0.2 4e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.9 CDS27253.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-C2H2 PF00096.26 CDS27254.1 - 3.2e-15 55.6 24.8 6e-06 26.4 2.9 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS27254.1 - 8e-11 41.9 30.2 1.3e-05 25.4 3.9 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS27254.1 - 2.5e-09 37.2 17.4 0.005 17.6 1.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS27254.1 - 5.7e-05 23.0 11.3 0.00059 19.8 0.5 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS27254.1 - 0.0014 18.9 8.2 0.34 11.2 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CDS27254.1 - 0.0049 17.1 7.4 0.06 13.7 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 CDS27254.1 - 0.037 14.4 0.3 0.037 14.4 0.3 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Arf PF00025.21 CDS27255.2 - 7.9e-69 230.6 0.0 8.7e-69 230.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS27255.2 - 2.8e-14 53.4 0.0 3.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS27255.2 - 5.3e-12 45.6 0.0 5.7e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDS27255.2 - 3.5e-11 42.9 0.0 4.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDS27255.2 - 7.8e-09 35.2 0.0 9.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CDS27255.2 - 2.4e-08 33.5 0.6 4e-07 29.5 0.2 2.4 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CDS27255.2 - 0.00049 20.2 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS27255.2 - 0.015 14.8 0.1 0.037 13.6 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain CorC_HlyC PF03471.17 CDS27255.2 - 0.064 13.3 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Transporter associated domain Maf1 PF09174.10 CDS27256.1 - 1.2e-40 139.5 6.1 1.9e-40 138.9 6.1 1.3 1 1 0 1 1 1 1 Maf1 regulator START PF01852.19 CDS27257.1 - 0.0054 16.2 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 START domain UCH PF00443.29 CDS27258.1 - 8.8e-46 156.5 0.6 1.4e-45 155.8 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS27258.1 - 4.6e-22 79.0 0.0 3.2e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CDS27258.1 - 4.6e-14 52.6 0.0 3.5e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal MATH PF00917.26 CDS27258.1 - 6.1e-13 48.9 0.5 1.7e-12 47.5 0.2 1.8 2 0 0 2 2 2 1 MATH domain USP7_ICP0_bdg PF12436.8 CDS27258.1 - 2.3e-09 36.9 0.0 3.9e-06 26.4 0.0 3.4 4 0 0 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 His_Phos_1 PF00300.22 CDS27260.1 - 1.5e-23 83.5 0.0 6.1e-22 78.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CDS27260.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) RNA_pol_3_Rpc31 PF11705.8 CDS27261.1 - 6.5e-07 29.8 10.6 1.1e-06 29.1 10.6 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PQQ_2 PF13360.6 CDS27262.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain UBX PF00789.20 CDS27263.1 - 3.4e-07 30.3 0.0 1.8e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 CDS27263.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like PC4 PF02229.16 CDS27264.1 - 1.9e-22 78.6 0.1 2.7e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Potassium_chann PF11404.8 CDS27264.1 - 0.19 11.6 1.6 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Potassium voltage-gated channel MBD_C PF14048.6 CDS27265.1 - 4.7e-15 56.1 0.3 9.3e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.19 CDS27265.1 - 3.5e-11 42.6 0.0 6.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain Glyco_hydro_47 PF01532.20 CDS27266.1 - 2e-107 360.0 0.0 4.7e-106 355.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Ion_trans PF00520.31 CDS27267.1 - 2.8e-123 409.9 85.4 1.2e-38 132.7 12.5 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CDS27267.1 - 0.32 9.6 64.6 0.026 13.2 0.6 7.7 6 1 0 6 6 6 0 Polycystin cation channel Guanylate_kin PF00625.21 CDS27268.1 - 2.7e-29 102.1 1.0 1.9e-28 99.4 1.0 2.4 1 1 0 1 1 1 1 Guanylate kinase Methyltransf_11 PF08241.12 CDS27268.1 - 0.02 15.5 0.1 0.14 12.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain VWA_3 PF13768.6 CDS27269.1 - 1.6e-08 34.7 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDS27269.1 - 2.1e-08 34.6 0.0 5.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDS27269.1 - 4.2e-06 27.3 0.0 8.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Nup96 PF12110.8 CDS27270.2 - 9.5e-80 267.8 1.0 1.4e-79 267.3 1.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CDS27270.2 - 1.6e-44 151.6 0.0 3.1e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CDS27270.2 - 5.1e-14 52.9 176.3 0.0012 19.6 22.6 7.6 2 1 3 5 5 5 4 Nucleoporin FG repeat region KCNQ_channel PF03520.14 CDS27272.1 - 3.6e-29 101.9 1.2 1.7e-28 99.8 1.2 2.0 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 CDS27272.1 - 1.4e-26 93.2 13.4 2.2e-26 92.6 13.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDS27272.1 - 9.1e-15 54.4 4.8 2.8e-14 52.8 4.8 1.8 1 0 0 1 1 1 1 Ion channel IQ PF00612.27 CDS27272.1 - 0.036 13.9 6.1 0.22 11.4 0.1 3.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF2798 PF11391.8 CDS27272.1 - 3.2 7.9 7.0 0.094 12.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) RNA_pol_L PF01193.24 CDS27273.1 - 3e-22 77.8 0.0 3.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 CDS27273.1 - 1.5e-21 75.9 0.0 6e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CDS27273.1 - 1.6e-17 63.9 0.0 3.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain DUF22 PF01629.16 CDS27273.1 - 0.19 11.4 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 Nucleopor_Nup85 PF07575.13 CDS27274.2 - 2.4e-47 161.8 3.3 3e-47 161.5 3.3 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin Calici_PP_N PF08405.11 CDS27274.2 - 0.032 13.1 0.2 0.11 11.3 0.1 1.9 2 0 0 2 2 2 0 Viral polyprotein N-terminal Ribosomal_L27A PF00828.19 CDS27275.1 - 9.3e-12 45.7 0.0 1.3e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_2 PF02230.16 CDS27283.1 - 1.2e-38 133.1 0.0 1.4e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 CDS27283.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 CDS27283.1 - 0.086 13.4 0.1 0.12 13.0 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.22 CDS27283.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 CDS27283.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CDS27283.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Gemin6 PF06372.12 CDS27284.1 - 7.8e-11 41.8 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Gemin6 protein AD PF09793.9 CDS27284.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Auts2 PF15336.6 CDS27285.1 - 0.19 11.8 0.6 1.5 8.9 0.6 2.0 1 1 0 1 1 1 0 Autism susceptibility gene 2 protein 7tm_1 PF00001.21 CDS27288.1 - 1.5e-06 27.8 0.9 1.7e-06 27.6 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS27288.1 - 0.0038 16.7 2.1 0.0049 16.3 2.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM72 PF16054.5 CDS27288.1 - 0.0067 16.2 0.3 0.0098 15.6 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein family 72 7TM_GPCR_Srw PF10324.9 CDS27288.1 - 0.014 14.7 3.1 0.019 14.3 3.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Pyridoxal_deC PF00282.19 CDS27291.1 - 1.8e-07 30.3 0.0 3.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HEAT PF02985.22 CDS27291.1 - 5.6e-07 29.3 5.2 3.5 8.1 0.1 6.5 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CDS27291.1 - 1e-06 29.1 2.1 0.00021 21.6 0.3 4.4 4 1 1 5 5 5 1 HEAT repeats TMEM131_like PF12371.8 CDS27291.1 - 0.23 11.7 0.4 19 5.6 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 131-like AMMECR1 PF01871.17 CDS27292.1 - 6.4e-50 169.0 0.0 7.9e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 EnY2 PF10163.9 CDS27293.1 - 2.3e-27 95.1 0.1 2.9e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Elong_Iki1 PF10483.9 CDS27294.1 - 1.1e-08 34.9 0.1 0.001 18.6 0.0 2.1 2 0 0 2 2 2 2 Elongator subunit Iki1 Sec3_C PF09763.9 CDS27294.1 - 0.2 10.0 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DnaB_C PF03796.15 CDS27296.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CDS27296.1 - 0.015 14.9 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NIF PF03031.18 CDS27297.1 - 1.2e-20 73.9 0.4 1e-19 70.8 0.4 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 CDS27297.1 - 0.00041 20.0 0.1 0.0011 18.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDS27297.1 - 0.0032 17.9 0.1 0.22 12.0 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain DUF4024 PF13216.6 CDS27297.1 - 0.18 11.8 0.0 0.49 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Alk_phosphatase PF00245.20 CDS27299.1 - 1.1e-104 350.7 0.0 1.2e-104 350.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDS27299.1 - 1.8e-05 24.3 0.0 4.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Phosphodiest PF01663.22 CDS27299.1 - 5.4e-05 22.9 0.0 8.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDS27299.1 - 0.034 13.5 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Alk_phosphatase PF00245.20 CDS27300.1 - 1.2e-101 340.7 0.0 1.3e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CDS27300.1 - 7.3e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RE_LlaMI PF09562.10 CDS27300.1 - 0.15 11.6 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 LlaMI restriction endonuclease UDG PF03167.19 CDS27301.1 - 2e-13 50.6 0.2 8.7e-13 48.5 0.0 2.2 3 0 0 3 3 3 1 Uracil DNA glycosylase superfamily DUF4179 PF13786.6 CDS27301.1 - 0.0091 16.4 2.5 7.4 7.1 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4179) zf-UBP PF02148.19 CDS27302.1 - 1.7e-20 73.1 3.4 3.4e-20 72.1 3.4 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein CENP-F_leu_zip PF10473.9 CDS27302.1 - 0.00044 20.3 14.1 0.00071 19.6 14.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.6 CDS27302.1 - 0.001 19.7 0.5 0.0015 19.1 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 CDS27302.1 - 0.0038 15.9 4.7 0.0041 15.9 4.7 1.1 1 0 0 1 1 1 1 AAA domain zf-UBP_var PF17807.1 CDS27302.1 - 0.01 15.6 0.7 0.021 14.5 0.7 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger DUF4472 PF14739.6 CDS27302.1 - 0.021 15.6 5.5 0.021 15.6 5.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) V-SNARE PF05008.15 CDS27302.1 - 0.028 14.8 4.1 0.028 14.8 4.1 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus KxDL PF10241.9 CDS27302.1 - 0.046 14.0 1.1 0.046 14.0 1.1 2.3 2 1 1 3 3 2 0 Uncharacterized conserved protein PHF5 PF03660.14 CDS27302.1 - 0.047 13.9 1.8 0.097 12.9 1.8 1.5 1 0 0 1 1 1 0 PHF5-like protein DUF4854 PF16146.5 CDS27302.1 - 0.073 13.4 5.3 0.22 11.8 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) CREPT PF16566.5 CDS27302.1 - 0.1 12.8 8.2 2.1 8.5 1.5 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4407 PF14362.6 CDS27302.1 - 0.15 11.4 10.1 0.18 11.1 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3795 PF12675.7 CDS27302.1 - 0.16 12.4 4.6 0.46 10.9 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) DUF2968 PF11180.8 CDS27302.1 - 0.17 11.5 9.0 0.3 10.7 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Blo-t-5 PF11642.8 CDS27302.1 - 0.18 11.7 6.6 1.1 9.3 0.1 2.7 1 1 1 3 3 3 0 Mite allergen Blo t 5 DUF2533 PF10752.9 CDS27302.1 - 0.28 11.7 4.2 1.9 9.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Laminin_II PF06009.12 CDS27302.1 - 0.35 10.9 8.3 0.18 11.8 4.1 2.1 1 1 1 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 CDS27302.1 - 0.35 10.4 7.4 0.48 9.9 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lipase PF00151.19 CDS27302.1 - 0.38 10.0 3.7 0.36 10.1 0.3 2.0 2 0 0 2 2 2 0 Lipase TPR_MLP1_2 PF07926.12 CDS27302.1 - 0.39 10.8 19.6 0.94 9.5 19.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 CDS27302.1 - 0.42 9.5 3.7 0.48 9.3 3.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sigma70_ner PF04546.13 CDS27302.1 - 0.46 10.3 8.9 4.9 7.0 3.7 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region T2SSM PF04612.12 CDS27302.1 - 0.53 10.3 5.8 0.22 11.5 2.2 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M DUF3496 PF12001.8 CDS27302.1 - 0.89 10.0 8.2 0.38 11.2 4.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) V_ATPase_I PF01496.19 CDS27302.1 - 1.1 7.1 6.1 1.3 6.8 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CDS27302.1 - 1.5 9.5 5.6 3.7 8.3 5.0 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Nsp1_C PF05064.13 CDS27302.1 - 1.8 8.4 10.3 0.34 10.7 4.6 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0242 PF06785.11 CDS27302.1 - 2.8 8.0 11.3 5 7.2 11.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AATF-Che1 PF13339.6 CDS27302.1 - 2.9 8.6 12.7 7.1 7.3 4.3 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4140 PF13600.6 CDS27302.1 - 3.4 8.2 9.0 1.8 9.1 1.4 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 CDS27302.1 - 8.7 5.5 6.4 17 4.5 5.9 1.6 1 1 1 2 2 2 0 TMPIT-like protein HR1 PF02185.16 CDS27302.1 - 9.8 6.4 12.4 1.1 9.4 3.8 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF719 PF05334.13 CDS27303.1 - 2.3e-19 70.3 0.4 7.8e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF719) SCHIP-1 PF10148.9 CDS27304.1 - 0.032 13.8 1.4 0.05 13.2 0.8 1.5 1 1 0 1 1 1 0 Schwannomin-interacting protein 1 DUF4047 PF13256.6 CDS27304.1 - 0.049 13.8 0.5 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF3510 PF12022.8 CDS27304.1 - 0.13 12.6 2.0 0.22 11.9 0.2 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) LOH1CR12 PF10158.9 CDS27304.1 - 0.19 11.7 1.8 0.54 10.3 0.2 2.3 1 1 1 2 2 2 0 Tumour suppressor protein A_deaminase PF00962.22 CDS27305.1 - 3.1e-110 368.6 0.1 1.3e-109 366.5 0.1 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase zf-C2H2 PF00096.26 CDS27306.1 - 5e-24 83.4 44.3 1.1e-05 25.5 1.4 5.9 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS27306.1 - 9e-21 73.3 36.0 1.1e-07 31.9 1.4 7.0 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS27306.1 - 3e-20 71.2 38.1 0.0007 20.2 1.9 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS27306.1 - 3.8e-11 42.7 31.9 0.00018 21.4 0.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-BED PF02892.15 CDS27306.1 - 5.2e-10 39.2 26.0 0.0097 15.9 1.8 5.4 3 1 2 5 5 5 4 BED zinc finger zf-C2H2_jaz PF12171.8 CDS27306.1 - 2.7e-09 37.0 18.5 0.12 12.7 0.1 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS27306.1 - 5.8e-08 32.9 21.1 0.0037 17.5 0.4 4.3 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 CDS27306.1 - 5.7e-05 23.2 18.5 2.9 8.1 0.6 5.3 5 0 0 5 5 5 1 AN1-like Zinc finger zf-met PF12874.7 CDS27306.1 - 0.00061 20.1 27.8 0.69 10.4 0.2 5.3 5 0 0 5 5 4 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDS27306.1 - 0.01 16.2 22.6 0.093 13.1 4.5 4.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 CDS27306.1 - 0.011 15.5 1.0 0.71 9.7 0.5 2.6 1 1 1 2 2 2 0 GAGA factor Metallothi_Euk2 PF12809.7 CDS27306.1 - 0.012 15.9 2.0 0.012 15.9 2.0 2.2 2 0 0 2 2 1 0 Eukaryotic metallothionein Prok-RING_1 PF14446.6 CDS27306.1 - 0.015 15.3 9.5 19 5.3 0.0 5.2 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 CDS27306.1 - 0.021 14.7 15.7 0.24 11.3 1.6 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PyrI_C PF02748.15 CDS27306.1 - 0.04 13.8 15.0 3.3 7.7 0.1 5.6 6 0 0 6 6 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 CDS27306.1 - 0.052 14.0 22.9 0.94 10.0 0.5 5.3 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf_ZIC PF18366.1 CDS27306.1 - 0.066 13.3 15.1 0.6 10.3 0.7 4.8 3 1 2 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 CDS27306.1 - 0.12 13.1 22.0 0.53 11.0 0.9 5.6 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 CDS27306.1 - 0.12 13.2 11.4 1.2 9.9 0.8 3.1 1 1 1 3 3 3 0 zinc-ribbon family DUF4428 PF14471.6 CDS27306.1 - 0.12 12.3 4.3 0.81 9.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-Sec23_Sec24 PF04810.15 CDS27306.1 - 0.28 11.2 12.6 23 5.2 0.2 4.8 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 CDS27306.1 - 0.29 11.3 18.6 2.4 8.3 2.0 4.9 3 2 2 5 5 5 0 Zinc ribbon domain DZR PF12773.7 CDS27306.1 - 0.35 10.9 12.1 6.6 6.8 9.8 2.9 2 1 0 2 2 1 0 Double zinc ribbon YhfH PF14149.6 CDS27306.1 - 0.43 10.6 4.9 40 4.3 0.2 3.5 3 0 0 3 3 3 0 YhfH-like protein HalOD2 PF18547.1 CDS27306.1 - 0.66 9.9 2.8 33 4.5 0.1 3.3 3 0 0 3 3 3 0 Halobacterial output domain 2 zf_UBZ PF18439.1 CDS27306.1 - 0.67 9.6 14.6 4.1 7.1 0.1 4.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 CDS27306.1 - 1 9.4 11.8 1e+02 3.0 0.0 4.3 2 1 0 2 2 2 0 CpXC protein Zf_RING PF16744.5 CDS27306.1 - 1.5 9.0 16.3 11 6.2 0.2 4.9 1 1 4 5 5 5 0 KIAA1045 RING finger HypA PF01155.19 CDS27306.1 - 1.5 8.8 10.9 14 5.7 3.9 3.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-MYST PF17772.1 CDS27306.1 - 1.8 8.3 10.5 7.9 6.2 0.0 4.6 4 1 1 5 5 5 0 MYST family zinc finger domain Desulfoferrod_N PF06397.12 CDS27306.1 - 2.3 7.9 9.0 2.4 7.9 0.2 3.7 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain HNH_5 PF14279.6 CDS27306.1 - 2.4 8.1 12.7 6.5 6.7 0.9 4.8 4 1 0 4 4 4 0 HNH endonuclease Zn_ribbon_SprT PF17283.2 CDS27306.1 - 3.3 7.7 11.6 1.6 8.7 5.1 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-CHCC PF10276.9 CDS27306.1 - 9.6 6.4 15.2 1.4 9.0 0.7 4.1 4 0 0 4 4 4 0 Zinc-finger domain DSL PF01414.19 CDS27307.1 - 4.2e-09 36.6 4.3 4.2e-09 36.6 4.3 4.5 3 1 1 4 4 4 1 Delta serrate ligand EGF PF00008.27 CDS27307.1 - 8.4e-08 32.4 43.3 1e-05 25.7 2.3 5.9 4 2 1 5 5 5 3 EGF-like domain hEGF PF12661.7 CDS27307.1 - 0.00051 20.6 3.2 0.00051 20.6 3.2 6.2 5 2 1 6 6 6 2 Human growth factor-like EGF EGF_2 PF07974.13 CDS27307.1 - 0.0079 16.5 9.7 0.0079 16.5 9.7 5.2 4 1 0 4 4 4 2 EGF-like domain RhoGEF PF00621.20 CDS27308.2 - 6.2e-20 72.2 0.0 1.4e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF2800 PF10926.8 CDS27308.2 - 0.11 11.8 0.8 0.24 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Cadherin PF00028.17 CDS27311.1 - 4.3e-88 289.9 0.0 1.7e-20 73.2 0.0 8.9 8 1 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.12 CDS27311.1 - 2.5e-22 78.5 0.0 1.2e-07 31.5 0.0 6.1 6 0 0 6 6 6 4 Cadherin-like Cadherin_3 PF16184.5 CDS27311.1 - 7e-07 29.2 3.1 0.056 13.4 0.1 5.1 5 0 0 5 5 5 3 Cadherin-like RET_CLD3 PF17812.1 CDS27311.1 - 0.1 12.9 0.2 69 3.7 0.0 3.9 3 0 0 3 3 3 0 RET Cadherin like domain 3 Pkinase PF00069.25 CDS27313.1 - 6.1e-63 212.6 0.0 9.6e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27313.1 - 3.9e-39 134.5 0.0 6.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS27313.1 - 2.7e-05 23.6 0.0 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CDS27313.1 - 0.00014 20.8 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDS27313.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 CDS27313.1 - 0.0021 18.3 7.7 0.0021 18.3 7.7 2.6 3 0 0 3 3 2 1 Ring finger domain PHD PF00628.29 CDS27313.1 - 0.084 12.8 6.0 0.26 11.2 6.0 1.8 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CDS27313.1 - 0.23 11.7 4.5 0.73 10.0 4.5 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain EGF_CA PF07645.15 CDS27313.1 - 0.97 9.7 3.5 2.5 8.4 2.5 2.2 2 0 0 2 2 1 0 Calcium-binding EGF domain Prok-RING_1 PF14446.6 CDS27313.1 - 1.9 8.5 5.2 0.51 10.3 1.1 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_SprT PF17283.2 CDS27313.1 - 2 8.4 4.0 0.98 9.4 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain SH3BP5 PF05276.14 CDS27314.1 - 1e-41 143.3 15.7 1.4e-41 142.9 15.7 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DNA_pol_lambd_f PF10391.9 CDS27314.1 - 0.038 13.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda PhaP_Bmeg PF09602.10 CDS27314.1 - 0.043 13.7 8.8 0.11 12.4 0.6 2.3 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4760 PF15956.5 CDS27314.1 - 0.044 13.9 0.3 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4760) FliJ PF02050.16 CDS27314.1 - 0.047 13.9 9.8 1.4 9.2 1.3 2.6 1 1 2 3 3 3 0 Flagellar FliJ protein Sec8_exocyst PF04048.14 CDS27314.1 - 0.06 13.2 3.2 0.47 10.3 0.5 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain THOC7 PF05615.13 CDS27314.1 - 0.083 13.2 14.4 2.4 8.4 13.8 2.5 1 1 0 1 1 1 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.22 CDS27314.1 - 0.29 11.4 8.6 1.3 9.3 0.3 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 CDS27314.1 - 0.57 9.5 9.9 3.4 6.9 0.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Remorin_C PF03763.13 CDS27314.1 - 0.63 9.9 4.2 4.4 7.2 0.7 2.4 2 0 0 2 2 2 0 Remorin, C-terminal region Baculo_PEP_C PF04513.12 CDS27314.1 - 1.1 9.3 7.4 5 7.2 0.3 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT20 PF14931.6 CDS27314.1 - 1.2 9.3 9.6 1.6 9.0 0.3 3.5 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Phage_lysis PF03245.13 CDS27314.1 - 1.3 9.1 7.2 4.8 7.3 0.2 3.1 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein CC2-LZ PF16516.5 CDS27314.1 - 1.4 9.3 5.9 3.3 8.1 0.3 3.4 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator LMBR1 PF04791.16 CDS27314.1 - 1.9 7.3 9.4 0.58 9.0 0.3 2.0 1 1 0 2 2 2 0 LMBR1-like membrane protein LOH1CR12 PF10158.9 CDS27314.1 - 1.9 8.5 5.5 0.56 10.2 0.4 2.5 2 2 0 2 2 2 0 Tumour suppressor protein Fez1 PF06818.15 CDS27314.1 - 3 8.3 10.0 1.8 9.0 7.2 1.9 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 CDS27314.1 - 3 7.1 13.0 1.8 7.8 2.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 CDS27314.1 - 3.9 8.1 8.2 0.75 10.4 1.1 2.9 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Duo1 PF08651.10 CDS27314.1 - 4.9 7.0 8.0 15 5.5 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Duo1 DUF745 PF05335.13 CDS27314.1 - 8.7 6.0 16.1 11 5.7 5.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) PAX PF00292.18 CDS27315.1 - 3.7e-63 211.0 0.6 6.2e-63 210.3 0.6 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDS27315.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CDS27315.1 - 0.0092 16.6 0.0 1.3 9.7 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain rve PF00665.26 CDS27316.1 - 5.4e-06 26.6 0.0 8.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS27316.1 - 0.0024 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SH3_11 PF18103.1 CDS27316.1 - 0.0026 17.9 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral integrase C-terminal SH3 domain InPase PF18823.1 CDS27317.1 - 0.078 12.7 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Inorganic Pyrophosphatase RRM_1 PF00076.22 CDS27318.1 - 1.9e-13 50.0 0.0 3.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_19 PF14559.6 CDS27319.1 - 5.2e-13 49.3 11.5 0.00036 21.0 0.0 7.0 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27319.1 - 5.8e-13 47.9 16.3 0.0014 18.6 0.0 8.3 8 1 1 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS27319.1 - 6.2e-09 36.0 19.5 8.4e-05 22.7 2.9 5.3 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDS27319.1 - 7.4e-07 29.4 16.5 1.4 9.3 1.0 8.1 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS27319.1 - 8.9e-07 28.5 17.3 0.12 12.3 0.0 7.5 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS27319.1 - 2.3e-06 27.9 5.6 0.57 11.1 0.0 6.6 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS27319.1 - 7.7e-05 22.6 12.7 1.4 9.3 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS27319.1 - 0.00042 20.8 12.2 0.38 11.5 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS27319.1 - 0.0027 17.3 0.3 0.17 11.6 0.3 3.7 3 0 0 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 CDS27319.1 - 0.008 16.2 1.4 0.008 16.2 1.4 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF2205 PF10224.9 CDS27319.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Short coiled-coil protein TPR_10 PF13374.6 CDS27319.1 - 0.13 12.1 2.5 9.7 6.2 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Paf67 PF10255.9 CDS27319.1 - 0.47 9.4 5.4 1.3 7.9 0.3 3.2 4 0 0 4 4 4 0 RNA polymerase I-associated factor PAF67 SIX1_SD PF16878.5 CDS27319.1 - 2.3 8.8 7.2 11 6.5 0.0 4.1 5 1 0 5 5 5 0 Transcriptional regulator, SIX1, N-terminal SD domain Aldedh PF00171.22 CDS27320.1 - 6.6e-62 209.5 0.0 8e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CDS27321.1 - 6.1e-88 295.3 0.1 6.8e-88 295.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2HC5 PF06221.13 CDS27322.1 - 7.9e-11 41.8 10.7 1.2e-10 41.2 10.7 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.14 CDS27323.1 - 7.8e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ASCH domain FKBP_C PF00254.28 CDS27325.1 - 5.6e-22 77.9 0.0 6.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WD40 PF00400.32 CDS27326.1 - 0.0017 19.1 4.7 0.77 10.7 0.9 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat F5_F8_type_C PF00754.25 CDS27327.1 - 2.6e-16 59.9 0.0 1.3e-15 57.6 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain LapA_dom PF06305.11 CDS27327.1 - 0.17 11.7 0.3 0.38 10.6 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 CDS27327.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 TMEM154 protein family DUF4006 PF13179.6 CDS27327.1 - 0.43 10.5 1.1 0.91 9.5 1.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) LAT PF15234.6 CDS27327.1 - 2.2 8.0 5.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells Transposase_1 PF01359.18 CDS27329.2 - 2e-13 50.0 0.2 3.2e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Cullin PF00888.22 CDS27330.1 - 1.6e-137 459.8 8.7 2.2e-137 459.3 8.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS27330.1 - 6.4e-20 71.0 1.9 2e-19 69.4 1.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF5043 PF16446.5 CDS27330.1 - 3.3 7.7 6.7 3.5 7.6 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5043) PHD PF00628.29 CDS27331.1 - 1.1e-09 38.1 13.0 1.1e-09 38.1 13.0 3.6 3 0 0 3 3 3 1 PHD-finger zf-CXXC PF02008.20 CDS27331.1 - 1.2e-07 31.6 38.2 1.4e-05 25.0 16.6 4.0 4 1 0 4 4 4 2 CXXC zinc finger domain PH PF00169.29 CDS27332.2 - 2.8e-13 50.3 0.1 9.6e-07 29.3 0.0 3.7 3 0 0 3 3 3 2 PH domain Thioredoxin_8 PF13905.6 CDS27332.2 - 0.0014 18.9 0.3 3.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like DUF1694 PF07997.11 CDS27332.2 - 0.0032 17.5 0.0 5 7.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1694) BAR_3 PF16746.5 CDS27332.2 - 0.0044 16.8 12.6 0.006 16.3 0.3 3.4 3 0 0 3 3 3 1 BAR domain of APPL family Herpes_U30 PF04523.13 CDS27332.2 - 0.0075 14.2 0.5 0.23 9.3 0.1 2.3 2 0 0 2 2 2 1 Herpes virus tegument protein U30 Lambda_CIII PF02061.16 CDS27332.2 - 0.021 14.9 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Lambda Phage CIII DUF1829 PF08862.10 CDS27332.2 - 0.049 14.1 0.1 25 5.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF1829 SelA PF03841.13 CDS27332.2 - 0.15 11.0 0.0 17 4.2 0.0 2.3 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase TRF PF08558.10 CDS27332.2 - 0.71 9.4 13.7 1.1 8.8 1.2 3.8 4 1 0 4 4 4 0 Telomere repeat binding factor (TRF) Clathrin-link PF09268.10 CDS27332.2 - 1 8.8 3.9 19 4.8 0.3 2.5 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Ets PF00178.22 CDS27333.1 - 2.9e-24 85.3 0.2 4.4e-24 84.8 0.2 1.3 1 0 0 1 1 1 1 Ets-domain DUF4652 PF15525.6 CDS27333.1 - 0.06 13.1 0.2 0.085 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) PI_PP_C PF18365.1 CDS27333.1 - 0.1 12.6 0.2 0.69 9.9 0.0 2.0 1 1 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Ets PF00178.22 CDS27334.1 - 5.4e-29 100.5 0.7 8.3e-29 99.9 0.7 1.3 1 0 0 1 1 1 1 Ets-domain Exonuc_VII_L PF02601.15 CDS27335.1 - 0.0063 16.1 9.2 0.0072 15.9 9.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4407 PF14362.6 CDS27335.1 - 0.067 12.5 9.6 0.15 11.4 9.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2190 PF09956.9 CDS27335.1 - 0.074 13.6 0.3 0.12 12.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) MPS2 PF17060.5 CDS27335.1 - 0.15 11.3 9.8 0.18 11.0 9.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 GCN5L1 PF06320.13 CDS27335.1 - 0.53 10.4 8.5 0.28 11.3 6.2 1.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Peptidase_M2 PF01401.18 CDS27335.1 - 0.55 8.8 6.8 0.64 8.6 6.8 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme GBP_C PF02841.14 CDS27335.1 - 1 8.7 18.0 0.69 9.3 15.8 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3552 PF12072.8 CDS27335.1 - 1 8.8 23.4 1.8 7.9 22.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Myb_DNA-bind_4 PF13837.6 CDS27335.1 - 1.1 9.7 6.9 3.9 7.9 6.4 2.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain YlqD PF11068.8 CDS27335.1 - 1.4 9.3 13.9 0.56 10.6 5.6 2.2 1 1 1 2 2 2 0 YlqD protein APG6_N PF17675.1 CDS27335.1 - 1.5 9.4 21.4 1.1 9.8 19.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region bZIP_Maf PF03131.17 CDS27335.1 - 3.1 8.4 12.4 12 6.4 4.1 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor PP2C PF00481.21 CDS27337.1 - 3.9e-20 72.6 0.0 4.7e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDS27337.1 - 1.5e-05 24.7 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C CAP PF00188.26 CDS27338.1 - 1.1e-23 84.5 7.9 1.5e-23 84.0 7.1 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family WW PF00397.26 CDS27338.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 WW domain CAP PF00188.26 CDS27339.1 - 7.3e-25 88.2 1.8 7.3e-25 88.2 1.8 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ras PF00071.22 CDS27340.1 - 6.3e-27 94.2 0.0 2.9e-26 92.0 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDS27340.1 - 6.5e-13 48.9 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDS27340.1 - 5.8e-06 26.4 0.0 1.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDS27340.1 - 0.0087 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CDS27340.1 - 0.015 14.5 0.0 0.04 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CDS27340.1 - 0.021 14.3 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 CDS27340.1 - 0.03 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 CDS27340.1 - 0.043 14.1 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS27340.1 - 0.047 14.1 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CDS27340.1 - 0.072 13.3 0.1 0.3 11.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CDS27340.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 CDS27340.1 - 0.17 11.9 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ferrochelatase PF00762.19 CDS27341.1 - 1.6e-87 293.6 0.0 3.2e-87 292.6 0.0 1.5 1 1 0 1 1 1 1 Ferrochelatase PS_Dcarbxylase PF02666.15 CDS27342.1 - 3.1e-57 193.4 0.0 3.9e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3422 PF11902.8 CDS27342.1 - 0.049 12.7 0.1 0.074 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) CLU PF13236.6 CDS27343.1 - 1.9e-73 246.9 0.0 3.1e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CDS27343.1 - 2e-46 158.2 0.1 4.1e-46 157.2 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CDS27343.1 - 4.8e-15 55.6 6.2 2.9e-06 27.5 0.3 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 CDS27343.1 - 5.7e-08 33.0 0.6 1.9e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 CDS27343.1 - 0.0001 22.0 5.5 0.023 14.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Rad60-SLD PF11976.8 CDS27343.1 - 0.0025 17.6 0.1 0.0067 16.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sterile PF03015.19 CDS27343.1 - 0.01 16.1 0.0 0.038 14.2 0.0 2.0 1 0 0 1 1 1 0 Male sterility protein TPR_MalT PF17874.1 CDS27343.1 - 0.011 15.1 0.9 0.019 14.4 0.9 1.2 1 0 0 1 1 1 0 MalT-like TPR region DUF727 PF05303.12 CDS27343.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_1 PF00515.28 CDS27343.1 - 4.2 7.4 5.4 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AKAP28 PF14469.6 CDS27344.1 - 1.6e-41 140.9 0.7 2.3e-41 140.3 0.7 1.2 1 0 0 1 1 1 1 28 kDa A-kinase anchor Adaptin_N PF01602.20 CDS27345.1 - 4.8e-109 365.3 5.7 6.2e-109 364.9 5.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CDS27345.1 - 4.2e-46 156.8 1.3 8.8e-46 155.8 1.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CDS27345.1 - 5.7e-29 100.6 0.0 1.1e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CDS27345.1 - 5.2e-14 52.4 0.8 0.00066 20.0 0.0 6.2 4 1 3 7 7 7 4 HEAT repeats Cnd1 PF12717.7 CDS27345.1 - 1.1e-06 28.8 7.2 0.00087 19.4 0.4 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDS27345.1 - 0.0033 17.6 5.3 9.5 6.8 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 CDS27345.1 - 0.0074 16.8 2.2 12 6.5 1.0 4.3 2 2 1 3 3 3 1 HEAT-like repeat Vps54 PF07928.12 CDS27345.1 - 0.052 14.0 0.3 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 Vps54-like protein PHD PF00628.29 CDS27346.1 - 0.00013 21.8 11.8 0.00033 20.5 11.8 1.7 1 0 0 1 1 1 1 PHD-finger GerE PF00196.19 CDS27346.1 - 0.017 14.7 0.0 0.054 13.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family zf-ANAPC11 PF12861.7 CDS27346.1 - 0.1 12.6 3.9 0.21 11.7 3.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CFEM PF05730.11 CDS27350.2 - 0.047 13.8 0.5 0.11 12.6 0.5 1.6 1 0 0 1 1 1 0 CFEM domain Kinesin PF00225.23 CDS27351.1 - 1.4e-79 267.5 0.0 3.3e-79 266.2 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDS27351.1 - 1.2e-18 67.5 0.0 3.4e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding AAT PF03417.16 CDS27351.1 - 0.013 15.2 1.6 0.031 14.0 1.6 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase BLI1 PF17324.2 CDS27351.1 - 0.039 14.6 4.6 0.11 13.1 4.6 1.8 1 0 0 1 1 1 0 BLOC-1 interactor 1 YbaB_DNA_bd PF02575.16 CDS27351.1 - 0.046 14.0 1.0 0.23 11.7 0.7 2.4 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family U62_UL91 PF17442.2 CDS27351.1 - 0.34 10.9 1.6 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins V_ATPase_I PF01496.19 CDS27351.1 - 7.7 4.3 16.9 0.063 11.2 6.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ank_5 PF13857.6 CDS27352.1 - 4.8e-09 36.3 0.1 4.7e-06 26.8 0.0 3.5 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS27352.1 - 4.2e-08 33.7 0.2 0.0063 17.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27352.1 - 4.3e-08 33.5 0.2 0.00035 21.1 0.0 3.9 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS27352.1 - 2.2e-05 24.5 0.1 0.87 10.4 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat SET PF00856.28 CDS27353.1 - 2.9e-07 31.1 1.1 1.3e-06 28.9 0.0 2.4 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.18 CDS27353.1 - 0.013 15.5 11.5 0.013 15.5 11.5 3.2 3 0 0 3 3 3 0 MYND finger TPR_1 PF00515.28 CDS27353.1 - 0.13 12.1 0.3 21 5.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5560 PF17715.1 CDS27355.2 - 0.033 13.6 1.2 0.045 13.2 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) RasGAP PF00616.19 CDS27356.2 - 2.8e-30 105.6 0.4 5.7e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF748 PF05359.11 CDS27356.2 - 0.11 12.7 0.1 28 4.8 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) Coagulase PF08764.10 CDS27356.2 - 0.58 10.3 2.0 3.1 7.9 0.4 2.1 2 0 0 2 2 2 0 Staphylococcus aureus coagulase FOXP-CC PF16159.5 CDS27356.2 - 0.7 10.6 3.0 3.4 8.4 3.0 2.2 1 0 0 1 1 1 0 FOXP coiled-coil domain Seryl_tRNA_N PF02403.22 CDS27356.2 - 3.3 8.0 7.4 2 8.7 3.0 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Homeodomain PF00046.29 CDS27357.2 - 1.3e-09 37.8 10.3 6.6e-08 32.3 10.3 2.8 1 1 0 1 1 1 1 Homeodomain An_peroxidase PF03098.15 CDS27358.1 - 2.7e-189 630.2 0.0 3.6e-189 629.8 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.16 CDS27358.1 - 1.8e-27 95.2 0.0 8.5e-13 48.2 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS27358.1 - 4.7e-27 94.4 0.7 8.3e-13 48.8 0.5 2.8 2 1 0 2 2 2 2 Immunoglobulin domain LRR_8 PF13855.6 CDS27358.1 - 8.4e-24 83.1 3.2 3.9e-13 48.9 0.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat Ig_2 PF13895.6 CDS27358.1 - 2.5e-15 56.6 0.3 6.2e-07 29.7 0.0 3.6 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CDS27358.1 - 4e-10 39.7 0.0 0.00065 19.8 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain LRR_4 PF12799.7 CDS27358.1 - 5.3e-09 36.2 5.3 0.00077 19.8 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS27358.1 - 5.9e-05 22.6 0.5 0.00011 21.8 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat V-set PF07686.17 CDS27358.1 - 0.00048 20.3 0.1 0.059 13.6 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS27358.1 - 0.00091 19.2 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain LRR_5 PF13306.6 CDS27358.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_5 PF16681.5 CDS27358.1 - 0.0014 19.0 0.0 0.013 15.9 0.0 2.4 3 0 0 3 3 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LRR_1 PF00560.33 CDS27358.1 - 0.012 16.0 2.5 77 4.5 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRRNT PF01462.18 CDS27358.1 - 0.4 10.4 4.7 0.44 10.3 2.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain NUP50 PF08911.11 CDS27358.1 - 0.74 10.5 2.7 2 9.2 2.7 1.7 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Pkinase PF00069.25 CDS27359.2 - 5.3e-23 81.7 0.0 6.5e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27359.2 - 8.3e-09 35.1 0.0 9.8e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS27359.2 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HLH PF00010.26 CDS27362.1 - 5.6e-15 55.0 0.7 1.5e-14 53.7 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4094 PF13334.6 CDS27362.1 - 0.22 11.9 0.8 0.58 10.6 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) zf-C2H2 PF00096.26 CDS27363.1 - 1.4e-05 25.3 20.9 0.00037 20.8 6.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS27363.1 - 0.00015 22.3 12.6 0.03 15.1 4.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS27363.1 - 0.0066 16.8 16.1 2.9 8.5 0.1 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS27363.1 - 0.012 15.9 1.8 4.9 7.6 0.0 3.1 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS27363.1 - 1 9.9 9.1 2.1 8.9 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CDS27363.1 - 5.6 7.1 7.8 12 6.0 0.0 2.4 3 0 0 3 3 3 0 Aberrant zinc-finger RVT_1 PF00078.27 CDS27364.2 - 3.4e-13 49.6 0.2 2.6e-09 36.9 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_20 PF12840.7 CDS27368.2 - 0.064 13.3 0.1 0.79 9.8 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain P2X_receptor PF00864.19 CDS27370.1 - 6.8e-99 331.4 0.0 8.7e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.21 CDS27370.1 - 0.045 14.1 2.7 0.12 12.8 2.1 2.1 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' P2X_receptor PF00864.19 CDS27371.1 - 1.6e-94 317.0 0.6 2e-94 316.7 0.6 1.0 1 0 0 1 1 1 1 ATP P2X receptor Tetraspanin PF00335.20 CDS27372.1 - 4.5e-20 72.4 4.6 4.9e-20 72.2 4.6 1.0 1 0 0 1 1 1 1 Tetraspanin family SicP-binding PF09119.10 CDS27372.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 SicP binding WW PF00397.26 CDS27373.1 - 1.4e-07 31.5 1.5 3.2e-07 30.3 1.5 1.6 1 0 0 1 1 1 1 WW domain Ribosomal_L16 PF00252.18 CDS27374.1 - 1.2e-14 54.5 0.0 2.9e-14 53.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L16p/L10e Thg1 PF04446.12 CDS27375.1 - 8.3e-33 113.1 0.0 1.5e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase BSMAP PF12280.8 CDS27375.1 - 0.55 10.4 12.1 1.4 9.1 3.6 2.6 1 1 1 2 2 2 0 Brain specific membrane anchored protein Thg1C PF14413.6 CDS27376.1 - 2.4e-44 150.4 0.8 3.2e-44 150.0 0.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 CDS27376.1 - 5.5e-06 26.4 1.1 1.6e-05 24.9 0.1 2.0 2 1 0 2 2 2 1 tRNAHis guanylyltransferase Ribosomal_L22 PF00237.19 CDS27377.2 - 0.0086 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ClpB_D2-small PF10431.9 CDS27377.2 - 0.028 14.5 0.2 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein MBT PF02820.18 CDS27378.1 - 3.2e-28 97.9 2.9 1.1e-15 57.7 0.0 4.5 4 0 0 4 4 4 3 mbt repeat SLED PF12140.8 CDS27378.1 - 6.6e-14 52.4 0.1 2e-13 50.8 0.1 1.8 1 1 0 1 1 1 1 SLED domain Methyltransf_15 PF09445.10 CDS27379.2 - 2.1e-30 105.5 0.0 6.5e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CDS27379.2 - 4.1e-09 36.4 0.0 7.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS27379.2 - 1.5e-08 35.2 0.0 4.6e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDS27379.2 - 4.7e-08 33.0 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 CDS27379.2 - 9.5e-06 26.2 0.0 2.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS27379.2 - 5.5e-05 23.1 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDS27379.2 - 7e-05 22.3 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 CDS27379.2 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 CDS27379.2 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein N6_Mtase PF02384.16 CDS27379.2 - 0.024 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_18 PF12847.7 CDS27379.2 - 0.026 14.5 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 CDS27379.2 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 CDS27379.2 - 0.09 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_12 PF08242.12 CDS27379.2 - 0.12 13.1 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 CDS27379.2 - 0.15 11.3 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase 7tm_1 PF00001.21 CDS27380.1 - 6.1e-12 45.4 8.0 7.9e-12 45.1 8.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM132D_C PF15706.5 CDS27380.1 - 0.015 15.0 2.8 2.4 8.0 0.3 3.2 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MurJ PF03023.14 CDS27380.1 - 0.42 9.2 6.9 2 6.9 1.7 2.1 2 0 0 2 2 2 0 Lipid II flippase MurJ Insulin_TMD PF17870.1 CDS27380.1 - 0.85 9.7 3.9 16 5.7 0.5 2.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DAP PF15228.6 CDS27382.2 - 0.46 11.7 3.0 0.33 12.1 0.6 2.0 2 0 0 2 2 2 0 Death-associated protein DUF4402 PF14352.6 CDS27382.2 - 1.1 10.0 4.7 2 9.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) SET PF00856.28 CDS27384.2 - 7.2e-12 46.0 0.0 3.4e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 CDS27384.2 - 0.0085 16.1 0.4 0.19 11.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS27384.2 - 2.1 8.3 5.0 2 8.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-MYND PF01753.18 CDS27384.2 - 3.1 8.0 26.3 0.043 13.9 10.2 3.5 2 2 1 3 3 3 0 MYND finger Pyrophosphatase PF00719.19 CDS27386.1 - 9.3e-62 207.6 1.4 1.2e-61 207.2 1.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF1938 PF09153.10 CDS27386.1 - 0.088 12.9 0.1 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Thioredoxin PF00085.20 CDS27387.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Poty_PP PF08440.10 CDS27387.1 - 0.0085 15.2 0.7 0.017 14.2 0.7 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein Rootletin PF15035.6 CDS27387.1 - 0.089 12.8 2.7 0.18 11.8 2.7 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion MIP-T3_C PF17749.1 CDS27387.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Vps8 PF12816.7 CDS27388.1 - 7.4e-17 61.5 0.1 6.1e-16 58.5 0.1 2.4 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CDS27388.1 - 1e-06 28.7 0.7 0.0022 17.9 0.1 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_8 PF13181.6 CDS27388.1 - 0.053 13.8 0.2 1.5 9.2 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27388.1 - 0.12 12.5 0.0 32 5.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS27388.1 - 0.15 12.2 0.0 0.75 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD PF00628.29 CDS27388.1 - 0.54 10.2 5.1 0.4 10.6 2.1 2.3 2 0 0 2 2 2 0 PHD-finger SET PF00856.28 CDS27389.1 - 6.3e-08 33.2 0.5 1.5e-07 32.0 0.5 1.7 1 0 0 1 1 1 1 SET domain CdiI_4 PF18624.1 CDS27389.1 - 0.067 13.7 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 CDI immunity protein DUF3123 PF11321.8 CDS27390.2 - 5.4e-15 56.1 22.9 6.5 7.5 0.0 12.4 12 0 0 12 12 12 9 Protein of unknown function (DUF3123) SH3_10 PF17902.1 CDS27390.2 - 1.5e-08 34.6 0.0 5.8e-08 32.7 0.0 2.1 1 0 0 1 1 1 1 SH3 domain FeoB_N PF02421.18 CDS27390.2 - 9.6e-05 22.0 10.7 86 2.6 0.0 8.2 9 0 0 9 9 9 0 Ferrous iron transport protein B AMP-binding_C_2 PF14535.6 CDS27390.2 - 0.0011 19.3 42.6 33 4.9 0.2 11.1 10 0 0 10 10 10 0 AMP-binding enzyme C-terminal domain DUF2155 PF09923.9 CDS27390.2 - 0.047 13.9 0.4 28 5.0 0.1 3.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF4795 PF16043.5 CDS27390.2 - 0.49 10.0 9.0 0.19 11.3 2.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) eIF_4EBP PF05456.11 CDS27390.2 - 0.66 9.9 4.8 29 4.6 0.4 3.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Adaptin_binding PF10199.9 CDS27390.2 - 2 9.1 6.9 1 10.0 2.1 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 COG2 PF06148.11 CDS27390.2 - 7.8 6.6 10.9 3.1 7.9 3.6 3.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4640 PF15480.6 CDS27391.2 - 0.087 12.6 1.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) Ig_3 PF13927.6 CDS27393.1 - 1.8e-33 114.9 7.0 2.7e-12 47.1 0.1 7.7 8 0 0 8 8 8 5 Immunoglobulin domain ig PF00047.25 CDS27393.1 - 2.5e-18 66.0 0.1 2.1e-08 34.2 0.0 6.2 6 0 0 6 6 6 2 Immunoglobulin domain I-set PF07679.16 CDS27393.1 - 3.2e-18 65.6 0.0 4.5e-09 36.3 0.0 5.3 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS27393.1 - 1.6e-17 63.6 5.5 0.00014 22.1 0.1 6.8 7 0 0 7 7 7 5 Immunoglobulin domain Ldl_recept_a PF00057.18 CDS27393.1 - 2.2e-15 56.6 35.4 1.4e-06 28.4 8.5 3.8 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A V-set PF07686.17 CDS27393.1 - 9e-12 45.1 0.5 0.028 14.6 0.1 7.0 6 3 0 6 6 6 3 Immunoglobulin V-set domain Ig_6 PF18452.1 CDS27393.1 - 0.086 12.4 0.2 8 6.1 0.0 3.7 5 0 0 5 5 5 0 Immunoglobulin domain LIM PF00412.22 CDS27395.1 - 1.6e-18 66.7 24.6 1.3e-13 51.0 1.5 3.3 3 0 0 3 3 3 3 LIM domain zinc-ribbons_6 PF07191.12 CDS27395.1 - 0.3 11.1 23.3 0.056 13.4 8.3 3.7 1 1 2 3 3 3 0 zinc-ribbons STb_secrete PF09075.10 CDS27395.1 - 0.97 9.6 4.4 3.5 7.8 0.3 2.9 3 0 0 3 3 3 0 Heat-stable enterotoxin B, secretory Ion_trans PF00520.31 CDS27398.2 - 8.7e-16 57.9 17.4 1.3e-15 57.3 17.4 1.2 1 0 0 1 1 1 1 Ion transport protein Asp_protease_2 PF13650.6 CDS27399.1 - 0.0054 17.3 0.0 0.019 15.6 0.0 2.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDS27399.1 - 0.017 15.7 0.0 0.052 14.1 0.0 1.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-H2C2_5 PF13909.6 CDS27400.1 - 6.6e-12 45.0 20.2 3.2e-07 30.0 2.4 4.3 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDS27400.1 - 3.7e-07 30.3 23.5 0.0063 16.9 0.8 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS27400.1 - 1.2e-06 28.7 18.7 0.00049 20.4 4.3 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS27400.1 - 2.1e-05 25.0 20.5 0.004 17.9 0.9 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDS27400.1 - 0.0094 16.2 2.1 0.0094 16.2 2.1 3.0 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 CDS27400.1 - 0.095 13.0 1.7 0.19 12.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon Lar_restr_allev PF14354.6 CDS27400.1 - 0.57 10.6 4.3 77 3.8 2.9 3.3 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 CDS27400.1 - 0.81 9.9 7.7 1.5 9.0 1.1 2.7 1 1 1 2 2 2 0 Zinc ribbon domain zf-MYST PF17772.1 CDS27400.1 - 4.1 7.1 6.1 11 5.7 0.2 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain Rad17 PF03215.15 CDS27401.1 - 2.3e-19 70.1 0.1 8.6e-19 68.2 0.1 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CDS27401.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 CDS27401.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain AAA_22 PF13401.6 CDS27401.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDS27401.1 - 0.038 13.9 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 CDS27401.1 - 0.052 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CDS27401.1 - 0.055 14.0 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Sin_N PF04801.13 CDS27402.1 - 2.5e-40 139.0 0.1 6.7e-38 131.0 0.1 2.5 3 0 0 3 3 3 2 Sin-like protein conserved region Cpn60_TCP1 PF00118.24 CDS27403.1 - 1e-142 476.3 8.9 1.2e-142 476.1 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_C50 PF03568.17 CDS27404.1 - 1.4e-47 162.7 0.3 1.4e-41 143.0 0.0 2.3 1 1 1 2 2 2 2 Peptidase family C50 BALF1 PF06861.11 CDS27404.1 - 1.6e-05 24.7 0.8 3.2e-05 23.7 0.8 1.4 1 0 0 1 1 1 1 BALF1 protein CHAT PF12770.7 CDS27404.1 - 0.041 13.3 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 CHAT domain COX4 PF02936.14 CDS27405.1 - 2.7e-41 140.8 0.0 3.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Complex1_LYR_2 PF13233.6 CDS27411.1 - 1.1e-05 26.1 0.1 1.4e-05 25.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CDS27411.1 - 0.015 15.3 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Ribonuc_P_40 PF08584.11 CDS27411.1 - 0.03 13.6 0.3 0.032 13.5 0.3 1.0 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit GAS2 PF02187.17 CDS27413.1 - 8.9e-30 102.6 0.2 2.5e-29 101.1 0.2 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 CDS27413.1 - 5.5e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain UCH PF00443.29 CDS27414.1 - 6.2e-55 186.5 0.0 1.3e-54 185.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS27414.1 - 1.3e-12 47.9 15.7 1.5e-10 41.2 14.4 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_5 PF13202.6 CDS27414.1 - 0.012 15.1 0.7 0.037 13.5 0.7 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CDS27414.1 - 0.078 12.6 1.6 0.17 11.5 0.6 2.1 2 0 0 2 2 2 0 EF hand NLE PF08154.12 CDS27414.1 - 0.087 13.4 0.1 28 5.3 0.0 3.1 2 0 0 2 2 2 0 NLE (NUC135) domain EF-hand_6 PF13405.6 CDS27414.1 - 0.089 12.8 2.7 0.11 12.5 0.6 2.4 2 0 0 2 2 2 0 EF-hand domain Mod_r PF07200.13 CDS27414.1 - 4.7 7.3 6.0 3.1 7.9 0.2 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.25 CDS27415.2 - 2e-18 66.7 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27415.2 - 8.6e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CDS27415.2 - 0.0074 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 UCH PF00443.29 CDS27416.1 - 4.8e-60 203.2 4.8 5.7e-60 203.0 4.8 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS27416.1 - 4e-31 108.8 10.5 6.8e-31 108.0 10.5 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Epimerase PF01370.21 CDS27417.1 - 2.3e-10 40.4 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDS27417.1 - 7.4e-09 35.0 0.0 1.5e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDS27417.1 - 5.9e-08 32.1 0.0 1.7e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDS27417.1 - 4.4e-06 26.7 0.0 8.5e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDS27417.1 - 1.4e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDS27417.1 - 0.00023 20.4 0.0 0.64 9.1 0.0 3.0 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 CDS27417.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 7tm_1 PF00001.21 CDS27418.1 - 2.3e-35 122.2 0.3 3.8e-35 121.5 0.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CDS27418.1 - 1.8e-08 34.5 2.6 1.8e-08 34.5 2.6 1.7 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srx PF10328.9 CDS27418.1 - 1.6e-05 24.7 9.8 1.6e-05 24.7 9.8 2.3 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 CDS27418.1 - 0.0013 18.3 4.5 0.0013 18.3 4.5 2.1 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srbc Actin PF00022.19 CDS27419.1 - 7.8e-125 416.7 0.0 5.2e-124 413.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDS27419.1 - 0.0026 16.6 0.1 0.21 10.3 0.1 2.5 2 1 0 2 2 2 2 MreB/Mbl protein C2 PF00168.30 CDS27420.1 - 4.5e-33 113.6 0.0 1.6e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDS27420.1 - 0.11 12.1 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain DUF3677 PF12432.8 CDS27421.1 - 4.4e-12 46.1 0.0 1.9e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) Cohesin_HEAT PF12765.7 CDS27421.1 - 0.28 11.5 6.9 0.19 12.1 0.4 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion EF-hand_8 PF13833.6 CDS27422.2 - 0.0012 18.6 0.1 0.0033 17.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Cadherin_3 PF16184.5 CDS27423.2 - 3.5e-27 94.6 4.0 0.00018 21.5 0.0 8.4 7 2 2 9 9 9 6 Cadherin-like Utp13 PF08625.11 CDS27425.1 - 4.8e-41 140.0 0.0 7.7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CDS27425.1 - 2.9e-36 122.8 31.6 1.6e-05 25.6 0.0 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27425.1 - 3.4e-08 33.7 0.5 0.58 10.5 0.0 5.9 5 2 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS27425.1 - 0.00018 20.3 4.3 0.0012 17.6 0.9 3.8 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDS27425.1 - 0.0046 15.8 1.3 8.5 5.0 0.0 4.2 2 1 0 3 3 3 1 Nup133 N terminal like Ge1_WD40 PF16529.5 CDS27425.1 - 0.0074 15.3 0.6 27 3.6 0.0 4.5 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDS27425.1 - 0.042 13.2 0.1 0.76 9.0 0.0 3.0 4 0 0 4 4 4 0 WD40-like domain eIF2A PF08662.11 CDS27425.1 - 0.062 13.2 0.0 0.5 10.2 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A LNS2 PF08235.13 CDS27426.1 - 2.7e-86 288.7 0.0 3.9e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDS27426.1 - 1.2e-27 95.8 0.0 2.6e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF4805 PF16063.5 CDS27426.1 - 0.026 13.9 0.8 0.046 13.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Acid_phosphat_B PF03767.14 CDS27426.1 - 0.074 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ubiquitin PF00240.23 CDS27427.1 - 1.7e-07 30.9 0.1 7.7e-07 28.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDS27427.1 - 8.8e-06 26.1 0.1 5.9e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Tyr_Deacylase PF02580.16 CDS27428.1 - 3.1e-23 82.9 0.0 3.5e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Kinesin PF00225.23 CDS27429.1 - 1.5e-109 365.9 1.1 2.9e-109 365.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDS27429.1 - 8.5e-28 97.2 0.3 3.3e-27 95.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 CDS27429.1 - 4.4e-09 36.8 0.1 4.4e-09 36.8 0.1 4.2 3 1 1 4 4 4 1 Kinesin-associated microtubule-binding Collagen_mid PF15984.5 CDS27429.1 - 0.024 14.4 5.8 0.25 11.1 0.7 2.8 2 0 0 2 2 2 0 Bacterial collagen, middle region FPN1 PF06963.12 CDS27429.1 - 0.09 11.3 0.9 0.17 10.4 0.9 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ApoO PF09769.9 CDS27429.1 - 0.36 10.8 2.8 47 3.9 0.2 4.2 3 1 0 3 3 3 0 Apolipoprotein O SMBP PF16785.5 CDS27429.1 - 1.9 8.7 4.2 1.3 9.3 0.4 2.5 2 0 0 2 2 2 0 Small metal-binding protein DEAD PF00270.29 CDS27431.1 - 2.6e-41 141.3 0.1 4.7e-41 140.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS27431.1 - 5.4e-28 97.6 0.5 1.1e-27 96.5 0.2 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDS27431.1 - 0.0041 16.4 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CDS27431.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Rhomboid PF01694.22 CDS27432.1 - 1.5e-23 83.5 13.1 3.4e-23 82.3 13.1 1.6 1 0 0 1 1 1 1 Rhomboid family M-inducer_phosp PF06617.13 CDS27432.1 - 0.024 13.9 0.2 0.047 13.0 0.2 1.4 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF2721 PF11026.8 CDS27432.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) zf-RING_2 PF13639.6 CDS27433.1 - 3.8e-07 30.3 12.1 9e-07 29.1 12.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS27433.1 - 2.6e-05 24.1 10.1 5.4e-05 23.1 10.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS27433.1 - 0.00021 21.1 11.1 0.00044 20.1 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS27433.1 - 0.0011 19.2 9.0 0.0034 17.6 9.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain WD40 PF00400.32 CDS27433.1 - 0.002 18.9 5.0 0.33 11.9 0.1 3.9 4 1 0 4 4 3 1 WD domain, G-beta repeat zf-RING_5 PF14634.6 CDS27433.1 - 0.0039 17.1 10.4 0.008 16.1 10.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDS27433.1 - 0.0045 17.0 3.3 0.01 15.9 3.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CDS27433.1 - 0.0093 16.1 7.9 0.038 14.1 8.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Methyltransf_25 PF13649.6 CDS27433.1 - 0.064 14.0 0.2 6.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain zf-Nse PF11789.8 CDS27433.1 - 0.067 13.0 3.2 0.15 11.9 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 CDS27433.1 - 0.074 13.2 7.5 0.2 11.9 7.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 CDS27433.1 - 0.089 12.9 3.3 0.37 10.9 3.3 2.1 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_4 PF14447.6 CDS27433.1 - 0.096 12.6 8.8 0.22 11.4 8.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDS27433.1 - 0.13 12.4 10.0 0.42 10.8 10.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 CDS27433.1 - 0.17 11.8 11.5 0.39 10.6 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CDS27433.1 - 0.31 11.2 2.0 0.85 9.8 2.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 CDS27433.1 - 0.47 10.1 7.6 1.1 9.0 7.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDS27433.1 - 0.83 9.5 8.3 2.2 8.1 8.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger Dynactin PF12455.8 CDS27434.1 - 1.1e-41 143.0 0.0 1.1e-41 143.0 0.0 4.2 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 CDS27434.1 - 3e-22 78.4 0.8 5.4e-22 77.6 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.6 CDS27434.1 - 0.0014 18.0 89.5 0.021 14.2 22.3 7.1 5 2 2 7 7 7 5 Growth-arrest specific micro-tubule binding ThiI PF02568.14 CDS27434.1 - 0.16 11.5 7.0 2.5 7.6 1.5 2.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) RAI16-like PF10257.9 CDS27435.2 - 3e-54 184.3 7.3 4.8e-54 183.6 7.3 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Pkinase PF00069.25 CDS27437.1 - 4.5e-25 88.5 0.0 4.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27437.1 - 5e-19 68.6 0.0 6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS27437.1 - 0.0041 16.5 0.0 0.0081 15.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS27437.1 - 0.0058 16.0 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS27437.1 - 0.087 11.6 0.2 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Rhodanese PF00581.20 CDS27438.1 - 1.7e-10 41.4 0.0 2.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain RUN PF02759.19 CDS27439.1 - 3.8e-29 101.4 0.0 9.3e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 RUN domain Pou PF00157.17 CDS27440.1 - 3.8e-31 106.9 0.0 8.4e-31 105.8 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDS27440.1 - 3.4e-18 65.2 2.6 1.2e-17 63.5 2.6 2.1 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDS27440.1 - 2.1e-05 24.8 0.1 0.0018 18.6 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain Homeobox_KN PF05920.11 CDS27440.1 - 0.0078 16.1 0.2 0.027 14.4 0.2 2.0 1 0 0 1 1 1 1 Homeobox KN domain N_NLPC_P60 PF12912.7 CDS27440.1 - 0.032 14.6 1.1 0.032 14.6 1.1 3.0 4 0 0 4 4 4 0 NLPC_P60 stabilising domain, N term MatE PF01554.18 CDS27441.1 - 6.9e-41 139.6 41.4 3.4e-24 85.3 9.7 3.1 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 CDS27441.1 - 0.00012 22.2 14.2 0.00012 22.2 14.2 4.6 3 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 CDS27441.1 - 0.011 15.8 1.4 0.011 15.8 1.4 3.5 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Ctr PF04145.15 CDS27441.1 - 0.45 11.1 5.3 14 6.2 0.0 2.9 3 0 0 3 3 3 0 Ctr copper transporter family EXS PF03124.14 CDS27442.1 - 1.4e-52 179.1 5.4 1.7e-52 178.8 5.4 1.1 1 0 0 1 1 1 1 EXS family NECFESHC PF16621.5 CDS27442.1 - 0.085 12.8 1.7 0.29 11.1 0.6 2.3 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Acetyltransf_1 PF00583.25 CDS27443.1 - 0.02 15.1 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CdhD PF03599.16 CDS27443.1 - 0.091 11.5 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit zf-CCCH_4 PF18044.1 CDS27444.1 - 6.8e-08 32.1 3.6 1.3e-07 31.3 3.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDS27444.1 - 1.7e-06 27.9 8.1 3e-06 27.1 8.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CDS27444.1 - 1.9e-06 27.7 3.3 3.3e-06 26.9 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDS27444.1 - 0.0027 18.4 1.4 0.0055 17.4 0.5 1.9 2 0 0 2 2 2 1 Torus domain Med26 PF08711.11 CDS27444.1 - 0.015 15.3 0.1 0.043 13.8 0.1 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DRIM PF07539.12 CDS27444.1 - 0.018 13.4 0.4 0.03 12.6 0.2 1.4 2 0 0 2 2 2 0 Down-regulated in metastasis zf-CCCH_2 PF14608.6 CDS27444.1 - 3.7 8.2 14.8 0.041 14.4 6.0 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 CDS27445.1 - 1.3e-58 194.7 2.7 2.1e-18 65.9 0.2 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS27445.1 - 6.1e-06 25.9 0.1 0.00032 20.3 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS27445.1 - 7.8e-05 22.7 1.9 0.44 10.7 0.1 5.0 4 3 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS27445.1 - 0.00015 21.7 0.8 2.6 8.1 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CDS27445.1 - 0.00083 19.3 0.2 0.83 9.6 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS27445.1 - 0.0086 16.1 0.1 2.1 8.4 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif TFIIF_alpha PF05793.12 CDS27446.1 - 2.4e-38 132.1 43.8 2.4e-38 132.1 43.8 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RVT_connect PF06815.13 CDS27446.1 - 0.1 12.9 0.5 0.45 10.8 0.2 2.1 2 0 0 2 2 2 0 Reverse transcriptase connection domain RabGAP-TBC PF00566.18 CDS27448.1 - 3e-30 105.5 5.2 9.6e-27 94.0 1.5 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RIB43A PF05914.12 CDS27449.1 - 8.7e-134 446.0 45.6 9.8e-134 445.8 45.6 1.0 1 0 0 1 1 1 1 RIB43A ANAPC4_WD40 PF12894.7 CDS27450.1 - 1e-05 25.8 0.4 5.1 7.5 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS27450.1 - 0.0008 20.2 8.0 0.65 11.0 0.0 6.7 8 0 0 8 8 8 2 WD domain, G-beta repeat Nop14 PF04147.12 CDS27451.1 - 2.5e-25 88.9 19.1 2e-14 52.9 3.4 2.4 2 1 0 2 2 2 2 Nop14-like family HAUS-augmin3 PF14932.6 CDS27451.1 - 0.46 10.0 6.5 0.14 11.7 1.3 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MFS_1 PF07690.16 CDS27452.1 - 2.2e-46 158.4 28.2 3e-46 158.0 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FmiP_Thoc5 PF09766.9 CDS27454.2 - 2.8e-139 464.5 13.0 8.9e-85 285.1 2.8 2.1 2 0 0 2 2 2 2 Fms-interacting protein/Thoc5 PI-TkoII_IV PF18714.1 CDS27454.2 - 0.02 14.3 5.7 7.2 6.1 0.1 4.0 2 2 1 4 4 4 0 DNA polymerase II intein Domain IV AAA_3 PF07726.11 CDS27454.2 - 0.037 13.9 0.0 16 5.3 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CREPT PF16566.5 CDS27454.2 - 0.058 13.6 9.1 1.7 8.8 0.4 3.2 2 2 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF896 PF05979.12 CDS27454.2 - 0.1 12.5 1.7 24 4.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF896) Transcrip_act PF04949.13 CDS27454.2 - 0.13 12.2 11.0 0.54 10.1 2.8 2.9 2 2 0 2 2 2 0 Transcriptional activator RP-C_C PF11800.8 CDS27454.2 - 0.17 12.0 6.9 3.3 7.8 0.1 3.7 3 0 0 3 3 3 0 Replication protein C C-terminal region BLOC1_2 PF10046.9 CDS27454.2 - 0.79 10.1 13.1 1.2 9.5 0.6 4.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 CDS27454.2 - 6.9 6.8 8.2 28 4.8 0.1 3.7 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 HSP70 PF00012.20 CDS27455.1 - 6.6e-260 863.4 12.8 7.4e-260 863.3 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDS27455.1 - 8.9e-19 67.5 0.4 1.1e-16 60.6 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDS27455.1 - 0.0008 19.8 4.0 0.59 10.6 0.0 3.0 3 2 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 CDS27455.1 - 0.0014 17.7 1.4 1.7 7.6 0.0 3.4 2 1 0 3 3 3 3 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CDS27455.1 - 0.075 12.3 0.1 0.075 12.3 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Innexin PF00876.18 CDS27457.2 - 3.4e-99 332.5 9.4 3.7e-98 329.0 9.4 1.9 1 1 0 1 1 1 1 Innexin Innexin PF00876.18 CDS27458.1 - 2.6e-103 346.0 9.6 2.9e-103 345.8 9.6 1.0 1 0 0 1 1 1 1 Innexin TRAM1 PF08390.11 CDS27458.1 - 1.6 8.5 4.9 4.6 7.0 0.3 2.5 2 0 0 2 2 2 0 TRAM1-like protein Innexin PF00876.18 CDS27459.1 - 8.9e-56 189.7 10.0 1.1e-55 189.4 10.0 1.0 1 0 0 1 1 1 1 Innexin BatA PF07584.11 CDS27459.1 - 0.099 13.0 1.0 0.25 11.7 1.0 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal CaMBD PF02888.16 CDS27459.1 - 0.11 12.7 3.4 2.1 8.6 0.0 3.1 3 0 0 3 3 3 0 Calmodulin binding domain CLASP_N PF12348.8 CDS27460.1 - 3.2e-34 118.5 5.6 2.1e-08 34.0 0.0 6.6 6 1 1 7 7 7 5 CLASP N terminal HEAT PF02985.22 CDS27460.1 - 2.4e-10 39.8 1.8 0.23 11.8 0.0 7.9 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 CDS27460.1 - 1.6e-08 34.8 3.7 6.7 7.2 0.0 7.7 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 CDS27460.1 - 2.3e-05 24.8 6.8 0.092 13.3 0.0 5.6 6 0 0 6 6 6 2 HEAT-like repeat TAN PF11640.8 CDS27460.1 - 0.00025 21.2 9.6 0.11 12.7 0.0 5.6 6 1 0 6 6 6 2 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 CDS27460.1 - 0.0014 18.2 1.1 2.8 7.5 0.0 5.2 4 2 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.7 CDS27460.1 - 0.088 13.1 0.2 1.1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion AflR PF08493.10 CDS27460.1 - 0.093 12.2 6.8 0.38 10.2 0.6 2.5 2 0 0 2 2 2 0 Aflatoxin regulatory protein RTP1_C1 PF10363.9 CDS27460.1 - 0.12 12.6 2.4 19 5.5 0.0 4.9 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 PLDc_2 PF13091.6 CDS27461.1 - 1.9e-15 56.9 0.5 1.1e-06 28.6 0.1 3.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDS27461.1 - 5.9e-15 54.7 2.3 2.2e-07 30.8 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 CDS27461.1 - 0.018 15.0 0.3 0.051 13.6 0.3 1.8 1 0 0 1 1 1 0 PX domain PLDc PF00614.22 CDS27462.1 - 3.1e-17 62.0 1.2 9e-09 35.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CDS27462.1 - 9.7e-14 51.4 0.0 1.5e-05 24.9 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain PX PF00787.24 CDS27462.1 - 1.6e-08 34.5 1.1 6.4e-08 32.6 1.1 2.1 1 1 0 1 1 1 1 PX domain PH PF00169.29 CDS27462.1 - 0.014 15.9 0.1 0.043 14.3 0.1 1.9 1 0 0 1 1 1 0 PH domain PBD PF00786.28 CDS27463.1 - 0.0027 18.0 0.1 0.0055 17.0 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain CAP_N PF01213.19 CDS27463.1 - 0.23 10.9 2.1 0.29 10.6 2.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CDS27463.1 - 0.58 10.2 4.0 0.82 9.7 4.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ebp2 PF05890.12 CDS27464.1 - 1.1e-68 231.7 21.6 1.6e-68 231.2 21.6 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF3585 PF12130.8 CDS27466.1 - 1.8e-15 57.3 21.7 2.8e-15 56.6 21.7 1.3 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain DUF2802 PF10975.8 CDS27466.1 - 0.075 13.2 4.1 0.14 12.3 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Fib_alpha PF08702.10 CDS27466.1 - 0.59 10.3 10.1 1.1 9.4 10.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CDS27466.1 - 0.61 10.8 6.6 0.29 11.9 3.7 1.9 1 1 1 2 2 2 0 Occludin homology domain DivIC PF04977.15 CDS27466.1 - 0.77 9.6 10.3 0.05 13.4 4.2 2.0 1 1 0 2 2 2 0 Septum formation initiator FapA PF03961.13 CDS27466.1 - 2.5 6.6 11.9 3.4 6.2 11.1 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A SPACA9 PF15120.6 CDS27466.1 - 4.7 7.0 8.0 5 6.9 1.0 2.3 1 1 1 2 2 2 0 Sperm acrosome-associated protein 9 V_ATPase_I PF01496.19 CDS27466.1 - 5.3 4.8 8.8 7.2 4.4 8.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDS27466.1 - 8 5.6 7.1 11 5.1 7.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Stork_head PF10264.9 CDS27467.1 - 2.1e-23 82.3 0.5 5e-23 81.1 0.5 1.7 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Pkinase PF00069.25 CDS27468.1 - 8.2e-15 54.9 0.1 2.5e-10 40.2 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27468.1 - 2.4e-09 36.9 0.0 0.00014 21.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS27468.1 - 0.019 14.3 0.1 0.2 11.0 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Bd3614-deam PF14439.6 CDS27468.1 - 0.28 11.3 1.4 1.9 8.5 1.2 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase XPC-binding PF09280.11 CDS27472.1 - 0.00015 21.4 0.0 0.51 10.1 0.1 2.3 2 0 0 2 2 2 2 XPC-binding domain PRCC PF10253.9 CDS27472.1 - 0.16 12.7 7.9 0.32 11.8 7.9 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 CDS27472.1 - 0.93 8.6 24.9 1.4 8.0 24.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pol_alpha_B_N PF08418.10 CDS27472.1 - 2 8.3 14.2 3.6 7.5 14.2 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RIFIN PF02009.16 CDS27472.1 - 7.4 6.4 8.4 15 5.3 8.4 1.6 1 0 0 1 1 1 0 Rifin Cellulase PF00150.18 CDS27473.1 - 1.7e-36 126.1 0.0 2.3e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CDS27473.1 - 2.9e-09 37.3 0.0 5.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 CDS27473.1 - 0.005 16.2 0.2 0.013 14.8 0.2 1.6 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_53 PF07745.13 CDS27473.1 - 0.014 14.4 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Laminin_G_2 PF02210.24 CDS27474.1 - 2.8e-27 95.8 1.3 1.9e-17 64.0 0.1 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 CDS27474.1 - 1.5e-23 83.4 0.0 2.1e-18 66.8 0.0 3.5 3 1 0 3 3 3 3 Laminin G domain EGF PF00008.27 CDS27474.1 - 1.2e-06 28.7 16.0 0.0044 17.3 6.1 3.0 2 1 0 2 2 2 2 EGF-like domain Laminin_G_3 PF13385.6 CDS27474.1 - 5.6e-06 26.6 0.1 0.0015 18.6 0.0 3.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EB PF01683.18 CDS27474.1 - 0.028 14.7 15.2 0.084 13.2 2.5 2.6 2 0 0 2 2 2 0 EB module hEGF PF12661.7 CDS27474.1 - 0.13 13.0 13.6 0.3 11.8 0.6 3.6 3 2 0 3 3 3 0 Human growth factor-like EGF GDPD PF03009.17 CDS27479.2 - 8.4e-54 183.0 0.0 1.2e-53 182.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 CDS27479.2 - 0.00018 21.4 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain TIMELESS PF04821.14 CDS27480.1 - 7.7e-62 209.1 10.2 1.4e-61 208.2 0.8 2.5 2 0 0 2 2 2 2 Timeless protein TIMELESS_C PF05029.13 CDS27480.1 - 5.9e-29 101.7 5.8 5.9e-29 101.7 5.8 4.8 4 1 1 5 5 5 1 Timeless protein C terminal region F-box PF00646.33 CDS27482.1 - 1.1e-06 28.4 1.3 1.1e-06 28.4 1.3 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDS27482.1 - 0.021 14.7 1.0 0.25 11.3 1.5 2.6 2 1 0 2 2 2 0 F-box-like WD40 PF00400.32 CDS27482.1 - 0.025 15.5 13.7 3.8 8.5 4.2 5.8 6 0 0 6 6 6 0 WD domain, G-beta repeat RNase_H PF00075.24 CDS27483.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNase H zf-RVT PF13966.6 CDS27483.1 - 0.11 13.2 0.4 0.18 12.5 0.3 1.6 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Pkinase PF00069.25 CDS27484.1 - 3e-24 85.8 0.0 4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDS27484.1 - 7.4e-09 34.9 0.0 8.6e-09 34.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDS27484.1 - 1.1e-08 34.7 0.0 1.8e-08 34.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDS27484.1 - 0.00043 20.3 0.0 0.094 12.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS27484.1 - 0.0082 15.5 0.0 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family 7tm_1 PF00001.21 CDS27485.1 - 1.3e-06 27.9 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS27485.1 - 0.0085 15.4 0.3 0.0085 15.4 0.3 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF829 PF05705.14 CDS27485.1 - 0.095 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Cadherin PF00028.17 CDS27486.1 - 5e-55 183.9 6.2 5.1e-13 49.3 0.0 7.1 6 1 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 CDS27486.1 - 8e-15 54.5 0.4 1.7e-07 31.0 0.0 5.3 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 CDS27486.1 - 0.0029 17.6 4.7 4 7.5 0.1 4.7 5 1 0 5 5 5 2 Cadherin-like Flagellin_IN PF07196.13 CDS27486.1 - 0.06 13.5 0.3 1.4 9.2 0.4 2.7 2 0 0 2 2 2 0 Flagellin hook IN motif Symplekin_C PF12295.8 CDS27488.1 - 7.2e-55 186.0 0.5 1.6e-54 184.8 0.5 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 CDS27488.1 - 2.3e-17 63.4 0.1 4.9e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Spore_III_AB PF09548.10 CDS27488.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF3453 PF11935.8 CDS27489.1 - 1.1e-71 241.1 0.7 1e-70 237.9 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.8 CDS27489.1 - 3.9e-65 219.4 0.8 1.3e-64 217.7 0.1 2.4 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal Snf7 PF03357.21 CDS27490.1 - 5.4e-32 110.8 17.2 5.4e-32 110.8 17.2 1.5 2 0 0 2 2 2 1 Snf7 zf-CCCH_6 PF18585.1 CDS27490.1 - 0.044 13.7 0.1 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 CheX PF13690.6 CDS27490.1 - 0.076 13.2 4.5 0.6 10.3 0.3 2.6 2 1 0 2 2 2 0 Chemotaxis phosphatase CheX DUF2250 PF10007.9 CDS27490.1 - 0.079 13.1 4.4 0.31 11.2 0.4 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) DASH_Spc19 PF08287.11 CDS27490.1 - 0.56 10.1 11.0 1.7 8.5 10.4 2.2 2 1 0 2 2 2 0 Spc19 TPD52 PF04201.15 CDS27490.1 - 1 9.0 7.3 1.9 8.1 6.9 1.6 1 1 0 1 1 1 0 Tumour protein D52 family DUF4407 PF14362.6 CDS27490.1 - 3.1 7.1 8.8 11 5.2 7.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FAM92 PF06730.11 CDS27495.1 - 0.02 14.3 0.4 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 FAM92 protein Ig_3 PF13927.6 CDS27497.1 - 2.7e-45 152.8 13.1 7.5e-07 29.7 0.7 10.3 9 2 1 10 10 10 7 Immunoglobulin domain I-set PF07679.16 CDS27497.1 - 4.2e-34 116.5 0.0 9.2e-06 25.6 0.0 9.6 9 1 0 9 9 9 6 Immunoglobulin I-set domain ig PF00047.25 CDS27497.1 - 2.4e-26 91.7 0.2 1.8e-05 24.8 0.0 8.8 8 1 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CDS27497.1 - 3.9e-23 81.6 7.8 0.00014 22.1 0.0 10.3 11 1 0 11 11 11 7 Immunoglobulin domain V-set PF07686.17 CDS27497.1 - 5.7e-16 58.7 2.8 0.0031 17.6 0.0 8.5 9 2 0 9 9 9 4 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS27497.1 - 7.5e-10 38.8 6.9 0.0019 18.2 0.0 7.1 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain fn3 PF00041.21 CDS27497.1 - 6.1e-07 29.7 0.1 2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Izumo-Ig PF16706.5 CDS27497.1 - 0.078 13.1 0.0 21 5.3 0.0 3.8 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain FLYWCH PF04500.16 CDS27498.1 - 0.00017 21.6 0.9 0.0003 20.8 0.9 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain WRKY PF03106.15 CDS27498.1 - 0.11 12.7 3.5 0.48 10.7 2.3 2.1 1 1 1 2 2 2 0 WRKY DNA -binding domain Alpha-amylase_C PF02806.18 CDS27499.1 - 2.5e-23 82.4 0.0 5.4e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CDS27499.1 - 2.8e-16 59.6 0.0 2.8e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDS27499.1 - 6.2e-15 55.6 0.1 3.3e-11 43.4 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain GHL6 PF14871.6 CDS27499.1 - 0.0086 16.2 0.3 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 AMPK1_CBM PF16561.5 CDS27499.1 - 0.079 13.2 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 CDS27500.1 - 2.2e-66 223.9 0.0 2.7e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27500.1 - 6.3e-33 114.1 0.0 8e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS27500.1 - 3.9e-07 29.7 0.0 6.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS27500.1 - 4.8e-06 26.7 0.2 6.6e-05 22.9 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDS27500.1 - 0.00045 19.4 0.0 0.00079 18.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CDS27500.1 - 0.0013 17.7 0.3 0.0019 17.2 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CDS27500.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDS27500.1 - 0.0024 17.3 0.1 0.0044 16.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS27500.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family tRNA-synt_2b PF00587.25 CDS27501.1 - 2.4e-13 50.5 0.0 4.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_8 PF13181.6 CDS27502.1 - 1.2e-08 34.5 1.2 0.029 14.6 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS27502.1 - 2.1e-07 30.5 5.7 0.0012 18.6 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27502.1 - 2.6e-06 27.1 6.0 0.00037 20.4 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDS27502.1 - 1.2e-05 25.3 0.3 0.24 11.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS27502.1 - 1.7e-05 25.3 0.8 0.0086 16.7 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS27502.1 - 0.001 19.7 3.4 2.5 9.1 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF2252 PF10009.9 CDS27502.1 - 0.04 13.0 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) TPR_9 PF13371.6 CDS27502.1 - 0.065 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDS27502.1 - 0.13 12.7 0.1 6.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS27502.1 - 0.52 10.5 3.6 31 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Adaptin_N PF01602.20 CDS27503.1 - 4e-154 514.1 13.6 5.2e-154 513.7 13.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDS27503.1 - 6.5e-63 211.6 16.0 1.7e-62 210.2 1.2 4.0 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CDS27503.1 - 3.3e-32 110.9 0.0 9e-32 109.5 0.0 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CDS27503.1 - 1.5e-18 67.0 4.5 5.8e-08 33.0 0.0 5.8 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 CDS27503.1 - 6e-12 44.7 8.8 0.0021 18.2 0.0 7.3 8 0 0 8 8 7 3 HEAT repeat Alpha_adaptinC2 PF02883.20 CDS27503.1 - 4.6e-08 33.4 0.4 9.7e-08 32.3 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 CDS27503.1 - 3.6e-07 29.7 1.6 0.00015 21.1 0.3 3.0 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CDS27503.1 - 8.8e-06 25.4 0.9 0.33 10.5 0.1 3.6 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.23 CDS27503.1 - 0.00011 22.1 2.4 0.35 11.0 0.1 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDS27503.1 - 0.00038 20.9 6.7 3.8 8.1 0.0 6.5 7 0 0 7 7 7 2 HEAT-like repeat AP3B1_C PF14796.6 CDS27503.1 - 0.0007 19.9 0.3 0.0096 16.2 0.1 2.5 1 1 1 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Arm_2 PF04826.13 CDS27503.1 - 0.0052 16.3 0.1 0.017 14.6 0.1 1.9 1 0 0 1 1 1 1 Armadillo-like RTP1_C1 PF10363.9 CDS27503.1 - 0.007 16.5 3.8 1.3 9.2 0.1 4.6 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Mo25 PF08569.11 CDS27503.1 - 0.0089 15.4 0.4 0.0089 15.4 0.4 2.2 2 0 0 2 2 2 1 Mo25-like Cohesin_HEAT PF12765.7 CDS27503.1 - 0.0092 16.3 0.0 33 4.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.7 CDS27503.1 - 0.03 14.2 3.0 0.068 13.1 0.1 2.9 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF848 PF05852.11 CDS27503.1 - 0.069 13.3 0.1 0.069 13.3 0.1 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) RasGEF_N_2 PF14663.6 CDS27503.1 - 0.079 13.4 0.5 6.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FRB_dom PF08771.11 CDS27503.1 - 0.17 12.3 1.2 33 5.0 0.0 2.7 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain zf-C4 PF00105.18 CDS27504.1 - 2.4e-46 156.1 36.4 7.2e-26 90.4 13.1 2.4 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS27504.1 - 2.2e-14 53.5 0.1 7.8e-14 51.7 0.1 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPH PF13868.6 CDS27505.1 - 0.079 11.5 0.5 0.092 11.2 0.5 1.0 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain ING PF12998.7 CDS27505.1 - 0.14 12.8 0.1 0.17 12.5 0.1 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Ig_3 PF13927.6 CDS27506.1 - 2.7e-66 220.2 0.3 5.8e-11 42.8 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 CDS27506.1 - 3.3e-60 200.1 0.0 4.8e-11 42.6 0.0 7.3 7 1 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS27506.1 - 2.7e-44 149.4 0.1 5.5e-07 29.8 0.0 6.5 5 1 1 6 6 6 6 Immunoglobulin domain ig PF00047.25 CDS27506.1 - 1.2e-29 102.3 0.0 0.00043 20.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.21 CDS27506.1 - 5.7e-23 81.1 4.4 1.3e-07 31.9 0.0 6.3 5 2 0 5 5 5 3 Fibronectin type III domain V-set PF07686.17 CDS27506.1 - 2e-12 47.2 9.8 0.041 14.0 0.0 10.1 7 5 1 9 9 9 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS27506.1 - 6.2e-07 29.4 0.4 1.3 9.2 0.0 5.4 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS27506.1 - 0.0012 18.3 0.0 5.3 6.7 0.0 4.0 4 0 0 4 4 4 1 Immunoglobulin domain Ig_5 PF16681.5 CDS27506.1 - 0.013 15.9 0.0 3.3 8.2 0.0 4.2 6 0 0 6 6 4 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CDS27506.1 - 0.021 14.9 0.1 5.6 7.1 0.0 3.5 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDS27506.1 - 0.16 12.5 1.3 74 4.0 0.0 4.6 5 0 0 5 5 5 0 Purple acid Phosphatase, N-terminal domain zf-C2H2_4 PF13894.6 CDS27507.1 - 2.8e-05 24.6 14.8 0.2 12.6 4.0 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS27507.1 - 4.9e-05 23.6 16.5 0.0039 17.6 3.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type Yippee-Mis18 PF03226.14 CDS27507.1 - 0.18 12.1 5.0 0.2 11.9 0.2 2.6 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mob1_phocein PF03637.17 CDS27509.1 - 1.6e-74 249.5 0.7 1.9e-74 249.3 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family Aldolase_II PF00596.21 CDS27510.1 - 4.1e-33 114.9 0.0 6.8e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PCI PF01399.27 CDS27511.1 - 2.5e-07 31.1 0.1 5.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 PCI domain HTH_Mga PF08280.11 CDS27511.1 - 0.036 14.1 2.0 0.094 12.8 2.0 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Recombinase PF07508.13 CDS27513.1 - 0.16 12.4 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Recombinase GGA_N-GAT PF18308.1 CDS27513.1 - 0.27 10.9 0.7 0.91 9.2 0.2 2.0 2 0 0 2 2 2 0 GGA N-GAT domain NADH_dehy_S2_C PF06444.11 CDS27515.1 - 0.086 13.4 0.4 12 6.5 0.1 2.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus Glypican PF01153.19 CDS27516.2 - 6.7e-34 117.6 0.2 6.7e-34 117.6 0.2 2.6 3 0 0 3 3 3 1 Glypican Deltameth_res PF16020.5 CDS27516.2 - 0.22 11.4 0.8 0.59 10.1 0.8 1.7 1 0 0 1 1 1 0 Deltamethrin resistance N_Asn_amidohyd PF14736.6 CDS27517.1 - 1.7e-33 115.9 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase N_Asn_amidohyd PF14736.6 CDS27518.1 - 1.5e-41 142.4 0.0 1.9e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase GSG-1 PF07803.11 CDS27518.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 GSG1-like protein INT_SG_DDX_CT_C PF15300.6 CDS27519.1 - 9.3e-16 57.4 0.1 1.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus rve_3 PF13683.6 CDS27520.1 - 0.16 11.7 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain WD40 PF00400.32 CDS27521.1 - 2.9e-17 62.7 11.1 0.0011 19.7 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27521.1 - 2.6e-14 53.3 1.4 0.00036 20.8 0.0 4.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CDS27521.1 - 0.017 14.5 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Aha1_N PF09229.11 CDS27522.1 - 3e-36 124.6 4.4 5.6e-36 123.8 4.4 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CDS27522.1 - 3.8e-21 75.6 0.5 1.5e-20 73.7 0.1 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Cass2 PF14526.6 CDS27522.1 - 0.02 15.1 0.3 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 Integron-associated effector binding protein DUF3523 PF12037.8 CDS27523.1 - 3.8e-90 301.9 26.1 3.8e-90 301.9 26.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 CDS27523.1 - 9.9e-23 81.0 0.0 2.8e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDS27523.1 - 3.6e-06 27.2 1.3 9.9e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDS27523.1 - 0.0002 20.8 0.6 0.0015 18.0 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CDS27523.1 - 0.0013 18.5 0.0 0.0043 16.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 CDS27523.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDS27523.1 - 0.0067 16.2 0.0 0.033 13.9 0.0 2.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CDS27523.1 - 0.01 16.1 1.9 0.93 9.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 CDS27523.1 - 0.014 15.4 2.1 0.018 15.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDS27523.1 - 0.017 15.1 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CDS27523.1 - 0.026 14.9 6.5 0.043 14.2 0.0 3.4 2 2 0 2 2 1 0 AAA ATPase domain AAA_25 PF13481.6 CDS27523.1 - 0.029 13.9 0.2 0.17 11.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CDS27523.1 - 0.03 14.1 0.0 0.087 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDS27523.1 - 0.033 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDS27523.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Gram_pos_anchor PF00746.21 CDS27523.1 - 0.086 12.8 0.1 5.4 7.1 0.2 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif AAA_18 PF13238.6 CDS27523.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.6 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CDS27523.1 - 0.21 12.0 0.4 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 CDS27523.1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CDS27523.1 - 0.58 9.9 0.0 0.58 9.9 0.0 3.0 2 1 0 2 2 1 0 AAA domain Tom5 PF10642.9 CDS27523.1 - 0.6 10.2 2.8 31 4.7 0.1 3.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Prenylcys_lyase PF07156.14 CDS27524.1 - 9.9e-48 163.1 0.0 1.5e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 CDS27524.1 - 9.4e-20 71.3 0.0 1.3e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDS27524.1 - 3.7e-10 39.9 0.1 7.9e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDS27524.1 - 8.5e-07 28.9 0.2 0.0023 17.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDS27524.1 - 0.0022 17.3 0.1 0.041 13.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDS27524.1 - 0.019 15.0 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CDS27524.1 - 0.089 11.9 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MoCF_biosynth PF00994.24 CDS27525.1 - 3e-29 101.5 0.0 4.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 CDS27525.1 - 1.3e-27 97.0 0.0 1.9e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CH PF00307.31 CDS27526.1 - 4.6e-26 91.1 0.2 9.4e-13 48.3 0.1 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS27526.1 - 0.00021 21.1 0.1 0.16 11.8 0.0 3.2 4 0 0 4 4 4 2 CAMSAP CH domain Med12-LCEWAV PF12145.8 CDS27526.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain CLP_protease PF00574.23 CDS27527.1 - 4e-80 268.0 0.0 4.7e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease dsrm PF00035.26 CDS27528.2 - 6.6e-17 62.0 2.2 4.3e-07 30.5 0.2 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif Helicase_C PF00271.31 CDS27528.2 - 1.4e-13 51.1 0.0 4.2e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDS27528.2 - 5.5e-13 49.1 0.0 1.4e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDS27528.2 - 7.9e-12 45.4 0.0 2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 CDS27528.2 - 1.9e-07 31.0 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS27528.2 - 0.0021 18.1 0.0 0.0077 16.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CDS27528.2 - 0.0036 16.7 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 CDS27528.2 - 0.037 14.4 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDS27528.2 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CDS27528.2 - 0.076 13.3 1.0 0.66 10.2 1.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDS27528.2 - 1.2 9.5 3.0 1.2 9.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain zf-RING_9 PF13901.6 CDS27529.1 - 3e-42 145.0 1.1 5.4e-42 144.1 1.1 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon C6_DPF PF10170.9 CDS27529.1 - 0.058 13.8 0.0 0.058 13.8 0.0 2.9 3 1 0 3 3 3 0 Cysteine-rich domain DnaG_DnaB_bind PF08278.11 CDS27529.1 - 0.16 12.6 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding LIM PF00412.22 CDS27529.1 - 0.27 11.5 6.3 0.11 12.8 2.1 2.4 2 0 0 2 2 2 0 LIM domain Paired_CXXCH_1 PF09699.10 CDS27529.1 - 1.1 9.1 4.4 0.27 11.0 0.7 2.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 CDS27529.1 - 1.4 9.0 4.9 1.3 9.1 0.5 2.9 3 1 0 3 3 3 0 Cytochrome c7 and related cytochrome c zf-HC5HC2H PF13771.6 CDS27529.1 - 1.4 9.2 7.4 0.15 12.3 1.0 2.5 3 0 0 3 3 3 0 PHD-like zinc-binding domain DUF1272 PF06906.11 CDS27529.1 - 1.5 9.0 10.1 3.7 7.7 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) VATC PF18716.1 CDS27529.1 - 2.2 8.2 9.6 1.1 9.1 0.7 3.9 4 0 0 4 4 4 0 Vms1-associating treble clef domain PTPA PF03095.15 CDS27530.1 - 1.4e-88 297.2 0.2 3.5e-88 295.9 0.2 1.5 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Plectin PF00681.20 CDS27531.1 - 0.00015 21.6 0.0 1.4 8.8 0.0 3.7 3 0 0 3 3 3 3 Plectin repeat CSTF1_dimer PF16699.5 CDS27533.1 - 6.1e-12 45.1 0.3 3.5e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Cleavage stimulation factor subunit 1, dimerisation domain zf-C2H2 PF00096.26 CDS27533.1 - 4.9e-11 42.4 23.3 0.0012 19.2 4.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS27533.1 - 3.8e-08 33.5 19.8 0.01 16.6 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS27533.1 - 1.6e-06 28.3 15.9 0.13 12.8 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 CDS27533.1 - 0.00093 19.5 9.8 0.065 13.6 10.7 2.9 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDS27533.1 - 0.0044 17.4 2.4 1.5 9.3 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type ATF7IP_BD PF16788.5 CDS27533.1 - 0.0051 17.0 1.1 0.0051 17.0 1.1 3.5 3 1 0 4 4 3 1 ATF-interacting protein binding domain zf-C2H2_jaz PF12171.8 CDS27533.1 - 0.14 12.5 11.3 0.78 10.1 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CDS27533.1 - 0.22 12.2 15.2 1 10.0 2.3 3.4 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats DUF2256 PF10013.9 CDS27533.1 - 0.26 11.4 6.3 34 4.7 0.5 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 CDS27533.1 - 1.2 9.1 10.3 0.5 10.3 0.2 2.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 CDS27533.1 - 3.4 7.5 17.5 0.62 9.9 1.6 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type Myb_DNA-binding PF00249.31 CDS27534.1 - 4.6e-06 26.7 0.1 1.1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS27534.1 - 0.00011 22.4 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1938 PF09153.10 CDS27534.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Slu7 PF11708.8 CDS27535.1 - 1.1e-98 330.3 7.1 1.1e-98 330.3 7.1 2.8 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 CDS27535.1 - 0.011 15.5 0.8 0.023 14.4 0.4 1.7 2 0 0 2 2 2 0 Zinc knuckle Rubella_E2 PF05749.11 CDS27535.1 - 0.055 12.9 0.9 0.088 12.3 0.9 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Chorion_2 PF03964.15 CDS27535.1 - 0.23 12.3 7.7 0.75 10.7 7.7 1.9 1 0 0 1 1 1 0 Chorion family 2 SSP160 PF06933.11 CDS27535.1 - 5.1 5.2 5.4 9.3 4.3 5.4 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RhoGAP-FF1 PF16512.5 CDS27538.1 - 0.039 14.6 0.1 0.07 13.8 0.1 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain DNApol_Exo PF18136.1 CDS27540.1 - 3.1e-90 302.2 0.0 4.8e-90 301.5 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CDS27540.1 - 3.1e-45 154.9 0.0 5.8e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DUF4430 PF14478.6 CDS27540.1 - 0.026 15.1 0.0 0.078 13.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DNA_pol_A_exo1 PF01612.20 CDS27540.1 - 0.032 13.9 0.1 0.12 12.1 0.1 2.0 1 1 0 1 1 1 0 3'-5' exonuclease UVR PF02151.19 CDS27541.1 - 1.9e-06 27.4 15.1 0.0009 18.9 5.8 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif XRCC1_N PF01834.16 CDS27541.1 - 5.8e-05 23.1 0.0 0.0012 18.8 0.0 3.0 3 1 1 4 4 4 1 XRCC1 N terminal domain CAF1 PF04857.20 CDS27541.1 - 0.019 14.1 1.2 0.035 13.3 1.2 1.4 1 0 0 1 1 1 0 CAF1 family ribonuclease zf_UBZ PF18439.1 CDS27541.1 - 0.039 13.5 2.3 3.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger F5_F8_type_C PF00754.25 CDS27541.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 F5/8 type C domain zf-Di19 PF05605.12 CDS27541.1 - 1.4 9.3 6.9 21 5.5 0.5 3.3 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 CDS27541.1 - 1.7 8.7 10.5 2.4 8.3 1.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CDS27541.1 - 3.9 7.0 6.6 1.9 8.0 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-TRAF PF02176.18 CDS27541.1 - 5.3 7.8 6.1 2.5 8.9 1.6 2.6 1 1 1 2 2 2 0 TRAF-type zinc finger zinc_ribbon_15 PF17032.5 CDS27541.1 - 6.4 7.6 7.2 16 6.4 2.9 3.0 1 1 2 3 3 3 0 zinc-ribbon family CENP-T_C PF15511.6 CDS27542.1 - 1.7e-08 34.5 0.1 2.4e-08 34.1 0.1 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDS27542.1 - 2.4e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDS27542.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CDS27542.1 - 0.00018 21.9 0.3 0.0002 21.7 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS27542.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS27542.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDS27542.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDS27542.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 CDS27543.1 - 7.9e-19 68.3 0.5 9.6e-19 68.0 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS27543.1 - 0.0063 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 CDS27543.1 - 0.049 13.7 0.2 0.059 13.4 0.2 1.2 1 0 0 1 1 1 0 YscO-like protein BRI3BP PF14965.6 CDS27543.1 - 0.06 12.9 0.2 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Negative regulator of p53/TP53 Histone_H2A_C PF16211.5 CDS27544.1 - 1.3e-16 60.0 0.2 2.6e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CDS27544.1 - 2.4e-16 60.3 0.5 6.5e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS27544.1 - 0.0031 17.7 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 CDS27544.1 - 0.051 13.5 0.0 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 LcrG protein DUF3071 PF11268.8 CDS27544.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3071) Spectrin PF00435.21 CDS27545.1 - 4.5e-60 200.7 74.2 2e-10 41.1 1.5 17.0 16 0 0 16 16 16 12 Spectrin repeat CH PF00307.31 CDS27545.1 - 1.9e-45 153.5 2.1 1.1e-22 80.3 0.0 5.0 6 0 0 6 6 6 2 Calponin homology (CH) domain PH_9 PF15410.6 CDS27545.1 - 1.6e-15 57.5 0.0 5.2e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CDS27545.1 - 2.4e-11 44.1 0.0 8.2e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 PH domain CAMSAP_CH PF11971.8 CDS27545.1 - 4.7e-09 36.0 0.0 5e-06 26.3 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain Osmo_CC PF08946.10 CDS27545.1 - 0.43 10.9 4.8 18 5.6 0.1 4.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil TAD2 PF18521.1 CDS27545.1 - 4.1 7.5 5.4 14 5.9 0.3 2.9 2 0 0 2 2 2 0 Transactivation domain 2 Annexin PF00191.20 CDS27546.1 - 2.5e-22 78.7 2.0 6.5e-14 51.8 0.1 2.2 2 0 0 2 2 2 2 Annexin Annexin PF00191.20 CDS27547.1 - 5.1e-05 23.3 0.2 0.00023 21.2 0.2 2.0 1 1 0 1 1 1 1 Annexin Annexin PF00191.20 CDS27548.2 - 4.8e-09 36.1 0.2 7.7e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Annexin Annexin PF00191.20 CDS27549.1 - 8.3e-85 278.8 10.8 7.1e-23 80.5 0.3 4.1 4 0 0 4 4 4 4 Annexin DUF5069 PF16798.5 CDS27549.1 - 0.013 15.7 0.2 3.9 7.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) PRTP PF01366.18 CDS27549.1 - 0.015 13.4 0.3 0.025 12.7 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein GutM PF06923.11 CDS27549.1 - 0.028 14.5 0.1 0.063 13.4 0.1 1.5 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) UBA_2 PF08587.11 CDS27549.1 - 0.045 13.9 4.7 0.36 11.0 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) YqeY PF09424.10 CDS27549.1 - 0.13 12.4 0.9 0.42 10.7 0.1 2.3 2 2 0 2 2 2 0 Yqey-like protein Annexin PF00191.20 CDS27550.1 - 6.3e-83 272.8 8.2 5.2e-23 80.9 0.3 4.3 4 0 0 4 4 4 4 Annexin Ist1 PF03398.14 CDS27550.1 - 0.031 14.2 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Regulator of Vps4 activity in the MVB pathway Annexin PF00191.20 CDS27551.1 - 2.2e-71 235.8 15.8 1e-22 80.0 0.5 4.9 4 1 0 4 4 4 4 Annexin YrbL-PhoP_reg PF10707.9 CDS27551.1 - 0.08 12.4 4.6 3.7 7.0 0.3 2.9 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL RTT107_BRCT_6 PF16771.5 CDS27551.1 - 0.26 11.5 3.0 5.4 7.2 0.1 3.0 2 1 1 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain KaiA PF07688.12 CDS27551.1 - 0.34 11.1 2.2 9 6.5 0.1 3.0 2 1 1 3 3 3 0 KaiA C-terminal domain Annexin PF00191.20 CDS27552.1 - 3.3e-58 193.7 0.6 3.3e-14 52.7 0.0 4.9 4 1 0 4 4 4 4 Annexin FAR1 PF03101.15 CDS27552.1 - 8.8e-05 23.1 1.3 0.00013 22.6 0.1 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF5575 PF17738.1 CDS27552.1 - 0.0003 19.9 0.1 0.00057 19.0 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5575) Pup PF05639.11 CDS27552.1 - 0.0075 17.2 0.9 0.024 15.5 0.5 2.1 2 0 0 2 2 2 1 Pup-like protein DUF2312 PF10073.9 CDS27552.1 - 0.037 13.7 4.5 16 5.2 0.0 4.7 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF5101 PF17031.5 CDS27552.1 - 0.89 9.7 3.7 1.4 9.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) DUF4536 PF15055.6 CDS27553.1 - 0.0031 17.7 3.1 0.0041 17.3 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) Ras PF00071.22 CDS27554.1 - 6.7e-58 194.9 0.0 7.8e-58 194.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS27554.1 - 5.2e-33 113.8 0.0 7.8e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS27554.1 - 2e-12 46.9 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS27554.1 - 1.5e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS27554.1 - 1.5e-05 24.9 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDS27554.1 - 2.8e-05 23.8 0.0 0.0039 16.7 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDS27554.1 - 3e-05 23.5 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CDS27554.1 - 0.0014 19.0 0.2 0.023 15.0 0.0 2.6 1 1 2 3 3 3 1 AAA domain cobW PF02492.19 CDS27554.1 - 0.0019 17.8 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CDS27554.1 - 0.0029 17.4 0.0 0.25 11.1 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CDS27554.1 - 0.0045 16.8 0.1 0.24 11.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDS27554.1 - 0.0066 16.8 0.0 0.0098 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 CDS27554.1 - 0.0088 15.2 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 CDS27554.1 - 0.01 15.3 0.1 0.02 14.3 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CDS27554.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDS27554.1 - 0.016 14.7 0.2 0.028 13.9 0.2 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CDS27554.1 - 0.019 15.4 0.0 0.21 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CDS27554.1 - 0.021 14.1 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 CDS27554.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDS27554.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 CDS27554.1 - 0.082 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 CDS27554.1 - 0.09 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 CDS27554.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CDS27554.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDS27554.1 - 0.17 12.4 0.0 0.42 11.1 0.0 1.6 2 0 0 2 2 2 0 ABC transporter WD40 PF00400.32 CDS27555.1 - 8.2e-19 67.6 17.3 0.0085 16.9 1.8 8.4 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27555.1 - 3.6e-10 40.0 0.0 0.008 16.5 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CDS27555.1 - 1.1e-05 25.0 1.7 0.6 9.4 0.1 3.9 3 1 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 CDS27555.1 - 0.00033 20.6 0.5 1.1 9.1 0.0 3.8 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDS27555.1 - 0.002 16.9 0.0 0.31 9.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDS27555.1 - 0.0079 15.2 0.1 1.9 7.4 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytotoxic PF09000.10 CDS27555.1 - 0.13 12.6 0.2 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Cytotoxic UQ_con PF00179.26 CDS27556.1 - 2.6e-45 153.5 0.0 4.3e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.6 CDS27556.1 - 5.8e-13 48.9 5.4 1.1e-12 48.1 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDS27556.1 - 1.1e-10 41.1 2.5 2.2e-10 40.1 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDS27556.1 - 2.9e-09 36.7 3.3 5.7e-09 35.7 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS27556.1 - 3.1e-08 33.3 4.6 7.1e-08 32.2 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS27556.1 - 1.9e-06 27.7 3.4 3.5e-06 26.9 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDS27556.1 - 1.2e-05 25.5 9.3 6.4e-05 23.2 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDS27556.1 - 4.6e-05 23.4 4.3 4.6e-05 23.4 4.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger PA PF02225.22 CDS27556.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.6 CDS27556.1 - 0.00019 21.2 4.5 0.00031 20.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS27556.1 - 0.0009 19.1 4.9 0.0018 18.1 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDS27556.1 - 0.0052 16.8 2.3 0.011 15.7 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CDS27556.1 - 0.28 11.5 4.5 0.57 10.5 4.5 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 CDS27556.1 - 0.29 11.2 3.5 0.78 9.8 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CDS27556.1 - 0.63 9.7 7.2 1.4 8.6 6.6 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CDS27556.1 - 0.84 9.8 5.1 1.9 8.6 5.1 1.7 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 CDS27556.1 - 2 8.6 4.2 6.2 7.0 4.2 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger PAP_central PF04928.17 CDS27557.1 - 1.5e-44 151.8 0.1 2.1e-44 151.4 0.1 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 CDS27557.1 - 0.0002 21.6 0.2 0.00066 19.9 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.15 CDS27557.1 - 0.00032 20.4 0.1 0.0017 18.1 0.0 2.0 1 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain AmpE PF17113.5 CDS27557.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE VMR2 PF17055.5 CDS27557.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral matrix protein M2 Nrap_D2 PF17403.2 CDS27557.1 - 0.11 12.2 0.0 0.44 10.3 0.0 1.9 2 1 0 2 2 2 0 Nrap protein PAP/OAS-like domain E1-E2_ATPase PF00122.20 CDS27558.1 - 6e-54 182.3 1.9 2.4e-53 180.3 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDS27558.1 - 4.1e-46 157.0 4.2 4.1e-46 157.0 4.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDS27558.1 - 1.5e-22 79.5 1.1 3.2e-22 78.4 1.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDS27558.1 - 3.3e-20 73.3 0.5 2.9e-19 70.2 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDS27558.1 - 9.5e-09 34.8 1.1 9.9e-07 28.4 0.0 3.1 2 1 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 CDS27558.1 - 4.6e-06 27.2 0.0 3.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDS27558.1 - 1.1e-05 25.3 1.8 4.1e-05 23.4 1.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BicD PF09730.9 CDS27558.1 - 0.0047 15.4 0.3 0.91 7.9 0.0 2.1 2 0 0 2 2 2 2 Microtubule-associated protein Bicaudal-D XPG_N PF00752.17 CDS27559.1 - 2.2e-23 82.6 0.0 4.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDS27559.1 - 1.9e-18 66.6 0.0 4.8e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CDS27559.1 - 0.00029 20.4 0.1 0.00057 19.4 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing DSPc PF00782.20 CDS27560.1 - 3.7e-12 46.2 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS27560.1 - 3.4e-05 24.0 0.0 4.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDS27560.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDS27560.1 - 0.00031 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 CDS27560.1 - 0.035 14.6 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half ERO1 PF04137.15 CDS27561.1 - 1.6e-110 369.6 0.2 2.2e-110 369.2 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Adap_comp_sub PF00928.21 CDS27562.1 - 1.3e-46 159.1 0.0 2.7e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ank_2 PF12796.7 CDS27563.1 - 2e-24 86.0 0.1 4e-11 43.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS27563.1 - 8e-15 53.5 0.7 3.2e-05 24.0 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CDS27563.1 - 1.4e-14 54.0 0.6 1.1e-08 35.1 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS27563.1 - 2e-14 53.7 0.1 9.2e-09 35.7 0.0 3.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS27563.1 - 1.5e-12 47.3 0.1 1.1e-05 25.6 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Clathrin PF00637.20 CDS27563.1 - 0.0018 18.2 1.2 0.042 13.7 0.1 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS EF-hand_1 PF00036.32 CDS27565.1 - 8.7e-26 87.5 18.8 6.2e-06 25.4 0.1 6.2 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CDS27565.1 - 5.6e-23 78.9 13.3 1.8e-05 24.3 0.0 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 CDS27565.1 - 2.6e-22 77.2 19.4 1.6e-05 24.2 0.2 5.8 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 CDS27565.1 - 4.8e-19 68.6 24.7 1.5e-09 38.1 4.1 3.7 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.6 CDS27565.1 - 6.3e-12 45.2 13.0 0.019 14.8 0.2 5.5 5 0 0 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS27565.1 - 0.00027 21.2 12.9 0.037 14.3 0.7 3.5 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region FumaraseC_C PF10415.9 CDS27565.1 - 0.02 15.3 1.2 18 5.8 0.1 3.5 3 0 0 3 3 3 0 Fumarase C C-terminus EFhand_Ca_insen PF08726.10 CDS27565.1 - 0.035 14.2 4.7 2.1 8.5 0.2 3.1 3 0 0 3 3 3 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.6 CDS27565.1 - 0.041 13.7 3.9 27 4.7 0.0 4.1 4 0 0 4 4 4 0 EF hand SHOCT PF09851.9 CDS27565.1 - 0.079 12.7 2.8 91 3.0 0.0 4.5 4 0 0 4 4 4 0 Short C-terminal domain PIG-L PF02585.17 CDS27566.1 - 5.4e-12 46.5 0.0 6.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.32 CDS27567.1 - 1.9e-45 151.9 6.0 9.8e-10 38.9 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CDS27567.1 - 6.3e-29 100.8 0.6 1e-28 100.1 0.6 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CDS27567.1 - 1.2e-15 57.5 0.0 0.00072 19.8 0.0 5.3 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS27567.1 - 9e-07 28.1 0.2 0.053 12.5 0.0 3.3 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CDS27567.1 - 5.8e-05 22.6 0.1 5.1 6.3 0.0 4.3 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CDS27567.1 - 0.011 15.7 0.1 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CDS27567.1 - 0.11 11.1 0.0 7.5 5.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ZYG-11_interact PF05884.12 CDS27567.1 - 0.18 11.2 0.1 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF5593 PF18007.1 CDS27569.1 - 0.079 13.7 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5593) DUF4576 PF15144.6 CDS27569.1 - 4.9 7.1 5.5 18 5.3 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) Ank_4 PF13637.6 CDS27570.1 - 3.6e-19 68.9 1.6 2.9e-10 40.5 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS27570.1 - 1.1e-18 67.5 0.6 4.6e-10 39.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS27570.1 - 2.9e-14 52.9 3.1 7.4e-07 29.3 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS27570.1 - 1.6e-13 49.5 1.8 0.0047 17.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CDS27570.1 - 1.9e-11 43.9 1.5 0.001 19.4 0.2 4.4 4 0 0 4 4 4 2 Ankyrin repeat ComA PF02679.15 CDS27570.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Tam41_Mmp37 PF09139.11 CDS27571.1 - 2.7e-71 240.7 0.0 3e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Cwf_Cwc_15 PF04889.12 CDS27572.2 - 7.2e-68 229.0 15.4 1.1e-67 228.3 15.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RVT_1 PF00078.27 CDS27572.2 - 3e-26 92.3 0.0 6.3e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDS27572.2 - 1.1e-25 89.9 0.1 2.6e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS27572.2 - 7.3e-25 86.9 1.2 3.9e-24 84.6 0.2 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase DUF2076 PF09849.9 CDS27572.2 - 2 8.4 5.9 3.6 7.5 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Thymosin PF01290.20 CDS27573.1 - 1.4e-13 50.3 15.8 8.2e-13 47.9 0.3 2.3 2 1 0 2 2 2 2 Thymosin beta-4 family Ras PF00071.22 CDS27575.1 - 1.1e-55 187.7 0.0 1.2e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS27575.1 - 9.4e-24 83.9 0.0 1.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS27575.1 - 3.1e-08 33.3 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS27575.1 - 0.00085 18.9 0.0 0.0019 17.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDS27575.1 - 0.0028 17.1 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS27575.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ldh_1_N PF00056.23 CDS27575.1 - 0.034 14.2 0.0 8.1 6.5 0.1 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain RsgA_GTPase PF03193.16 CDS27575.1 - 0.096 12.6 0.0 0.55 10.1 0.0 2.0 1 1 0 2 2 2 0 RsgA GTPase Cyt-b5 PF00173.28 CDS27577.1 - 4.8e-10 39.4 0.0 6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain E3_binding PF02817.17 CDS27577.1 - 0.02 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain Med26 PF08711.11 CDS27578.1 - 2.8e-13 49.6 0.1 9.3e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ArsA_ATPase PF02374.15 CDS27580.1 - 2.8e-106 355.1 0.0 3.4e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDS27580.1 - 6.2e-12 45.8 0.0 8.9e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CDS27580.1 - 1.5e-11 44.5 0.0 6.4e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CDS27580.1 - 1.2e-05 24.9 0.0 3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CDS27580.1 - 6.2e-05 22.6 0.4 0.00037 20.0 0.0 2.2 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CDS27580.1 - 0.00022 20.8 0.0 0.00053 19.5 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 CDS27580.1 - 0.0013 17.9 0.2 0.0098 15.1 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 CDS27580.1 - 0.036 13.6 0.1 0.067 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDS27580.1 - 0.041 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CDS27580.1 - 0.084 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 CDS27580.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 CDS27580.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CDS27580.1 - 0.17 12.3 0.0 0.76 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain T-box PF00907.22 CDS27581.1 - 4.3e-79 265.1 0.6 6.8e-79 264.4 0.6 1.3 1 0 0 1 1 1 1 T-box rve PF00665.26 CDS27582.1 - 0.00096 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Arginase PF00491.21 CDS27584.1 - 5.6e-58 196.7 0.0 7.2e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family Guanylate_kin PF00625.21 CDS27585.1 - 4.3e-37 127.5 0.0 6.9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 CDS27585.1 - 2.5e-13 50.2 0.0 6.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS27585.1 - 0.00018 21.8 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS27585.1 - 0.00032 20.2 0.0 0.00083 18.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 CDS27585.1 - 0.00097 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CDS27585.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SNARE PF05739.19 CDS27586.1 - 5.6e-05 23.1 0.2 0.0001 22.2 0.2 1.5 1 0 0 1 1 1 1 SNARE domain ATP-synt_E PF05680.12 CDS27587.1 - 4.3e-13 49.4 0.1 5e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF4337 PF14235.6 CDS27587.1 - 0.039 14.1 0.7 0.049 13.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LRRFIP PF09738.9 CDS27588.1 - 3.2e-39 135.2 23.9 3.2e-39 135.2 23.9 2.5 2 1 0 2 2 2 1 LRRFIP family KASH_CCD PF14662.6 CDS27588.1 - 6.1e-05 22.9 6.6 6.1e-05 22.9 6.6 3.0 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Cep57_CLD_2 PF14197.6 CDS27588.1 - 0.0027 17.7 7.2 0.0027 17.7 7.2 5.6 4 2 2 6 6 6 1 Centrosome localisation domain of PPC89 GIT_CC PF16559.5 CDS27588.1 - 0.19 11.6 11.5 0.051 13.5 3.1 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 CDS27588.1 - 0.38 11.0 37.0 0.45 10.7 9.8 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4706 PF15797.5 CDS27588.1 - 2 9.0 0.0 2 9.0 0.0 3.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4706) Phage_GP20 PF06810.11 CDS27588.1 - 2.2 8.1 25.5 0.25 11.1 4.2 4.3 3 2 1 4 4 4 0 Phage minor structural protein GP20 DUF4686 PF15742.5 CDS27588.1 - 3.7 6.6 36.0 0.018 14.2 12.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4686) DUF4407 PF14362.6 CDS27588.1 - 4.2 6.6 28.5 0.086 12.2 12.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CDS27588.1 - 6 7.4 11.0 3 8.4 0.3 4.3 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Rx_N PF18052.1 CDS27588.1 - 8.9 6.7 15.5 0.061 13.6 3.5 3.0 2 1 1 3 3 3 0 Rx N-terminal domain Misat_Tub_SegII PF10644.9 CDS27589.1 - 2.2e-11 44.1 0.0 4.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS27589.1 - 3.3e-05 23.6 0.0 6.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Feld-I_B PF09252.10 CDS27589.1 - 0.14 12.1 0.1 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Allergen Fel d I-B chain TACC_C PF05010.14 CDS27590.1 - 1.3e-15 57.7 26.4 2.6e-15 56.7 26.4 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Syntaxin-6_N PF09177.11 CDS27590.1 - 0.21 12.1 5.1 1.2 9.7 5.1 2.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SlyX PF04102.12 CDS27590.1 - 1 10.1 5.9 5.2 7.8 5.9 2.2 1 0 0 1 1 1 0 SlyX FF PF01846.19 CDS27591.2 - 1.1e-50 169.6 48.5 1.6e-14 53.8 4.2 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.26 CDS27591.2 - 9e-23 80.1 16.6 4.4e-08 33.1 0.6 3.8 3 0 0 3 3 3 3 WW domain EF-hand_14 PF17959.1 CDS27591.2 - 0.11 12.8 0.2 0.56 10.6 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain RhoGAP-FF1 PF16512.5 CDS27591.2 - 0.38 11.4 16.5 0.24 12.1 0.2 4.3 3 1 1 4 4 4 0 p190-A and -B Rho GAPs FF domain DUF4366 PF14283.6 CDS27591.2 - 6.2 6.9 5.6 4.4 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Aldedh PF00171.22 CDS27592.1 - 2.2e-97 326.5 0.0 2.8e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CDS27592.1 - 0.17 11.8 0.2 0.41 10.6 0.2 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-H2C2_2 PF13465.6 CDS27594.1 - 0.016 15.6 0.1 0.016 15.6 0.1 8.4 11 0 0 11 11 11 0 Zinc-finger double domain zf-C2H2_9 PF16293.5 CDS27594.1 - 0.097 12.5 0.0 0.097 12.5 0.0 7.7 6 1 2 8 8 8 0 C2H2 type zinc-finger (1 copy) AAA_13 PF13166.6 CDS27594.1 - 0.17 10.5 1.3 0.29 9.7 1.3 1.3 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 CDS27594.1 - 0.19 12.7 78.5 0.35 11.8 0.1 12.5 12 0 0 12 12 12 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS27594.1 - 0.23 12.0 53.9 0.61 10.7 1.7 11.0 10 0 0 10 10 10 0 Zinc finger, C2H2 type zf-met PF12874.7 CDS27594.1 - 0.64 10.5 7.8 32 5.1 0.7 4.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 CDS27594.1 - 2 8.5 15.3 24 5.0 0.0 4.2 3 0 0 3 3 3 0 BED zinc finger RasGEF_N PF00618.20 CDS27595.2 - 1.9e-29 101.9 0.4 4.6e-13 49.3 0.0 3.2 3 0 0 3 3 3 2 RasGEF N-terminal motif RasGEF PF00617.19 CDS27595.2 - 2.9e-22 79.7 0.0 5.4e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain PH PF00169.29 CDS27595.2 - 2.1e-06 28.2 0.0 0.72 10.4 0.0 3.7 3 0 0 3 3 3 2 PH domain PH_10 PF15411.6 CDS27595.2 - 0.00012 22.3 0.0 0.00043 20.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain TINF2_N PF14973.6 CDS27595.2 - 0.012 15.9 0.6 9.2 6.6 0.0 2.8 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus HTH_16 PF12645.7 CDS27595.2 - 0.14 12.3 0.0 42 4.3 0.0 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain Cas6b_C PF17262.2 CDS27595.2 - 0.15 12.1 0.0 33 4.6 0.0 2.5 2 0 0 2 2 2 0 Cas6b C-terminal domain N6-adenineMlase PF10237.9 CDS27596.1 - 7.9e-20 71.3 1.3 2.7e-18 66.3 0.1 2.2 2 0 0 2 2 2 2 Probable N6-adenine methyltransferase CENP-L PF13092.6 CDS27596.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DHHC PF01529.20 CDS27596.1 - 0.88 9.7 26.0 3.9 7.6 11.9 2.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Cadherin PF00028.17 CDS27597.2 - 3.5e-66 219.7 0.1 5.8e-14 52.3 0.0 9.4 7 3 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS27597.2 - 2.2e-13 49.9 0.0 3e-06 27.0 0.0 5.8 6 0 0 6 6 6 3 Cadherin-like Cadherin_3 PF16184.5 CDS27597.2 - 0.0013 18.7 4.4 2.8 8.0 0.2 5.4 5 0 0 5 5 5 2 Cadherin-like RET_CLD1 PF17756.1 CDS27597.2 - 0.016 15.5 0.0 32 4.8 0.0 4.1 5 0 0 5 5 5 0 RET Cadherin like domain 1 Ribosomal_S17 PF00366.20 CDS27598.1 - 9.2e-26 89.8 5.0 1.3e-25 89.3 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CDS27598.1 - 1.9e-22 79.4 8.0 1.9e-22 79.4 3.8 2.7 2 1 0 2 2 2 1 Ribosomal_S17 N-terminal zf-nanos PF05741.13 CDS27599.1 - 1e-25 89.7 4.1 1.6e-25 89.1 4.1 1.3 1 0 0 1 1 1 1 Nanos RNA binding domain Viral_helicase1 PF01443.18 CDS27599.1 - 0.12 12.2 0.2 0.19 11.4 0.2 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-C2H2_2 PF12756.7 CDS27599.1 - 0.19 12.1 2.4 2 8.8 0.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Endonuclease_7 PF02945.15 CDS27599.1 - 0.19 11.7 1.3 0.41 10.6 1.0 1.7 2 0 0 2 2 2 0 Recombination endonuclease VII zf-Di19 PF05605.12 CDS27599.1 - 0.53 10.6 4.4 2.6 8.4 0.7 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_1 PF00133.22 CDS27600.2 - 3.1e-34 118.2 0.1 6.3e-17 61.1 1.4 5.3 3 2 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDS27600.2 - 1.2e-19 70.3 0.0 3.1e-16 59.1 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-ribbon_3 PF13248.6 CDS27600.2 - 0.00067 19.0 2.8 0.19 11.2 0.2 2.5 2 0 0 2 2 2 2 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 CDS27600.2 - 0.0026 17.8 2.7 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain Anticodon_1 PF08264.13 CDS27600.2 - 0.0079 16.2 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Zn-ribbon_8 PF09723.10 CDS27600.2 - 0.012 15.7 1.2 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 CDS27600.2 - 0.022 14.7 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon tRNA-synt_1f PF01921.18 CDS27600.2 - 0.045 12.7 0.0 1.6 7.6 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 CDS27600.2 - 0.089 12.1 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Nudix_N_2 PF14803.6 CDS27600.2 - 0.22 11.5 0.8 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf_Rg PF17915.1 CDS27600.2 - 0.67 9.4 2.7 0.36 10.3 0.1 1.9 2 0 0 2 2 2 0 Reverse gyrase zinc finger Auto_anti-p27 PF06677.12 CDS27600.2 - 0.74 10.0 3.4 9 6.6 0.1 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 CDS27600.2 - 1.2 8.7 4.1 4.4 6.9 0.4 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Cadherin PF00028.17 CDS27601.1 - 3.7e-52 174.7 0.2 5.3e-12 46.0 0.0 7.9 7 1 0 7 7 7 5 Cadherin domain Cadherin_2 PF08266.12 CDS27601.1 - 4.5e-05 23.2 0.0 0.013 15.3 0.0 4.2 4 0 0 4 4 4 1 Cadherin-like DUF2754 PF10953.8 CDS27601.1 - 0.11 12.8 0.5 0.2 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) RNA_pol PF00940.19 CDS27602.2 - 8.4e-190 631.0 0.0 2e-127 425.5 0.0 3.5 2 1 1 3 3 3 3 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDS27602.2 - 4.8e-27 95.2 0.1 8.2e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal MerR-DNA-bind PF09278.11 CDS27602.2 - 0.011 16.2 0.2 1.9e+02 2.7 0.0 4.7 4 0 0 4 4 4 0 MerR, DNA binding UPF0149 PF03695.13 CDS27602.2 - 0.014 15.7 1.1 15 5.8 0.0 4.2 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0149) DUF2385 PF09539.10 CDS27602.2 - 0.15 12.6 0.1 0.44 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF1638 PF07796.11 CDS27602.2 - 0.26 11.3 2.7 36 4.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1638) DEAD PF00270.29 CDS27603.1 - 1.3e-43 148.8 0.1 2.3e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS27603.1 - 5.8e-31 107.1 1.4 2.1e-30 105.3 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS27603.1 - 1.5e-05 25.1 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDS27603.1 - 0.0051 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS27603.1 - 0.0084 16.5 0.0 0.023 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 CDS27603.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 CDS27603.1 - 0.026 14.5 0.1 0.06 13.3 0.1 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 CDS27603.1 - 0.05 12.8 0.2 0.076 12.2 0.2 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TRAPP PF04051.16 CDS27605.1 - 4.9e-12 45.8 0.0 7.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Y_phosphatase PF00102.27 CDS27606.1 - 1.4e-123 411.0 0.0 4.7e-79 265.3 1.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDS27606.1 - 7.3e-23 80.7 0.9 4.3e-06 27.0 0.2 3.8 3 0 0 3 3 3 3 Fibronectin type III domain DSPc PF00782.20 CDS27606.1 - 2.2e-06 27.5 0.1 0.00025 20.9 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS27606.1 - 0.0024 18.0 0.4 0.026 14.6 0.0 2.6 3 0 0 3 3 3 1 Inositol hexakisphosphate Pur_ac_phosph_N PF16656.5 CDS27606.1 - 0.024 15.2 1.3 0.24 12.0 0.1 3.0 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Cyclin_N PF00134.23 CDS27606.1 - 0.13 12.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain YejG PF13989.6 CDS27607.1 - 0.06 13.8 2.8 0.17 12.4 0.6 2.9 1 1 1 2 2 2 0 YejG-like protein Matrilin_ccoil PF10393.9 CDS27607.1 - 0.31 10.9 8.9 0.16 11.9 0.4 4.3 3 2 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4041 PF13250.6 CDS27607.1 - 0.38 10.6 4.3 31 4.5 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) NPV_P10 PF05531.12 CDS27607.1 - 0.41 11.1 0.0 0.41 11.1 0.0 6.1 4 3 1 6 6 6 0 Nucleopolyhedrovirus P10 protein MRP-S23 PF10484.9 CDS27612.2 - 1.1e-09 38.6 0.0 2.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Lactamase_B_2 PF12706.7 CDS27612.2 - 3e-09 36.7 0.1 0.00042 19.9 0.0 3.4 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDS27612.2 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 CDS27612.2 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease MFAP1 PF06991.11 CDS27614.1 - 1.2e-70 237.8 24.0 1.2e-70 237.8 24.0 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DUF1681 PF07933.14 CDS27615.2 - 8.4e-43 145.6 0.0 1.2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WD40 PF00400.32 CDS27616.2 - 2.4e-25 88.3 15.0 0.00034 21.4 0.4 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27616.2 - 4.6e-08 33.2 6.9 0.012 15.9 0.1 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS27616.2 - 9.1e-05 21.6 1.3 0.12 11.3 0.0 3.2 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein B3_4 PF03483.17 CDS27618.2 - 1.5e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain PI3_PI4_kinase PF00454.27 CDS27619.2 - 2.4e-37 129.1 0.0 5.8e-37 127.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DFRP_C PF16543.5 CDS27620.1 - 1.1e-21 77.0 2.9 1.1e-21 77.0 2.9 3.6 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CDS27620.1 - 4.1e-09 37.1 9.7 2.7e-06 28.0 2.7 3.0 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CDS27620.1 - 6.2e-09 35.6 20.1 1.1e-07 31.6 4.5 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 CDS27620.1 - 1.9e-08 34.0 11.4 1.4e-07 31.3 0.5 3.5 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDS27620.1 - 1.8e-07 30.8 14.1 5.5e-06 26.1 1.0 3.4 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDS27620.1 - 2.7e-05 24.3 1.1 0.0084 16.3 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDS27620.1 - 0.0018 18.7 17.9 0.012 16.0 2.8 3.1 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger TPD52 PF04201.15 CDS27622.1 - 5.7e-19 68.3 2.1 6.3e-19 68.1 2.1 1.0 1 0 0 1 1 1 1 Tumour protein D52 family CYTH PF01928.21 CDS27622.1 - 0.014 15.4 1.4 0.021 14.8 1.4 1.3 1 0 0 1 1 1 0 CYTH domain DUF87 PF01935.17 CDS27622.1 - 0.023 14.8 0.9 0.027 14.6 0.9 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain DUF5082 PF16888.5 CDS27622.1 - 0.093 13.0 2.6 0.14 12.4 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Latarcin PF10279.9 CDS27622.1 - 0.18 12.3 0.8 0.5 10.8 0.8 1.9 1 1 0 1 1 1 0 Latarcin precursor HIP1_clath_bdg PF16515.5 CDS27622.1 - 0.24 12.0 5.2 0.42 11.3 0.4 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 rRNA_proc-arch PF13234.6 CDS27622.1 - 0.48 10.3 4.5 2 8.3 0.3 2.0 1 1 1 2 2 2 0 rRNA-processing arch domain YgaB PF14182.6 CDS27622.1 - 0.75 10.2 5.9 4.3 7.8 0.2 2.8 1 1 2 3 3 3 0 YgaB-like protein TMEM132D_C PF15706.5 CDS27623.2 - 7.2e-09 35.3 0.0 2.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM132 PF16070.5 CDS27623.2 - 0.0099 15.3 0.0 1.8 7.8 0.0 2.6 2 0 0 2 2 2 2 Transmembrane protein family 132 Ribosomal_L32p PF01783.23 CDS27624.1 - 0.0068 16.6 0.9 0.0099 16.1 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family ETRAMP PF09716.10 CDS27625.1 - 0.016 15.3 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NEMP PF10225.9 CDS27626.1 - 0.029 14.1 0.4 0.053 13.2 0.4 1.3 1 0 0 1 1 1 0 NEMP family Cyt-b5 PF00173.28 CDS27627.1 - 2.6e-15 56.3 0.0 4.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 CDS27627.1 - 1.5e-08 34.8 0.0 1.1e-07 32.1 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CDS27627.1 - 1.6e-07 31.9 0.0 3.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CDS27627.1 - 4e-05 23.8 0.0 0.0015 18.7 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Kazal_1 PF00050.21 CDS27627.1 - 0.015 15.3 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain WLM PF08325.10 CDS27627.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 WLM domain Cofilin_ADF PF00241.20 CDS27628.1 - 2.3e-15 56.5 0.1 2.6e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Beta-Casp PF10996.8 CDS27629.1 - 2.7e-24 85.6 0.0 8.6e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CDS27629.1 - 1.3e-19 70.3 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CDS27629.1 - 1.4e-17 63.3 0.0 8.3e-17 60.9 0.0 2.3 3 0 0 3 3 3 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CDS27629.1 - 5.4e-07 29.3 0.5 1.4e-06 28.0 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDS27629.1 - 1.1e-06 28.8 0.6 0.0011 19.0 0.3 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 CDS27629.1 - 0.0062 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family zf-TAZ PF02135.16 CDS27630.1 - 7.9e-11 42.3 10.1 1.1e-10 41.8 10.1 1.2 1 0 0 1 1 1 1 TAZ zinc finger KIX PF02172.16 CDS27630.1 - 7.5e-09 35.8 0.2 1.8e-08 34.6 0.2 1.6 2 0 0 2 2 2 1 KIX domain KIX_2 PF16987.5 CDS27630.1 - 0.2 11.7 0.2 0.41 10.7 0.2 1.5 1 1 0 1 1 1 0 KIX domain Pkinase_Tyr PF07714.17 CDS27631.1 - 1.5e-42 145.7 0.0 4.8e-40 137.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS27631.1 - 1.6e-26 93.2 0.0 1.6e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ig_3 PF13927.6 CDS27631.1 - 9.3e-08 32.6 0.8 4.6e-05 23.9 0.3 4.3 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 CDS27631.1 - 0.011 15.8 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain DUF4448 PF14610.6 CDS27631.1 - 0.028 14.2 0.1 0.082 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FXR_C1 PF16096.5 CDS27631.1 - 0.22 11.8 1.0 0.59 10.4 1.0 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 HLH PF00010.26 CDS27632.1 - 7.2e-05 22.7 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PTA_PTB PF01515.19 CDS27633.1 - 0.047 13.0 0.4 0.061 12.6 0.4 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase LSDAT_euk PF18139.1 CDS27634.2 - 2.7e-35 122.1 0.1 1.1e-20 74.2 0.0 3.7 2 1 1 3 3 3 2 SLOG in TRPM Ion_trans PF00520.31 CDS27634.2 - 1.2e-17 64.0 17.6 1.2e-16 60.7 18.0 2.0 1 1 1 2 2 2 2 Ion transport protein LSDAT_prok PF18171.1 CDS27634.2 - 2.3e-09 36.8 0.5 0.0034 16.7 0.0 2.9 3 0 0 3 3 3 2 SLOG in TRPM, prokaryote PKD_channel PF08016.12 CDS27634.2 - 0.00091 18.0 11.4 0.0018 17.1 11.4 1.4 1 1 0 1 1 1 1 Polycystin cation channel DUF2615 PF11027.8 CDS27634.2 - 0.18 11.9 0.1 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Exo_endo_phos_2 PF14529.6 CDS27635.1 - 4e-12 46.0 1.1 7.5e-12 45.1 1.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS27635.1 - 1.1e-05 25.1 0.0 4.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CDS27636.2 - 4.7e-12 45.9 0.1 8.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDS27637.1 - 7.4e-09 35.9 1.0 5.9e-07 29.8 0.1 2.6 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 CDS27637.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Urm1 PF09138.11 CDS27638.1 - 5.6e-32 110.0 0.0 6.2e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CDS27638.1 - 9.9e-06 26.1 0.0 1.3e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 CDS27639.1 - 4.3e-06 27.4 5.1 0.013 16.3 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 CDS27639.1 - 0.0015 18.4 0.2 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.8 CDS27639.1 - 0.0078 14.9 0.3 5.8 5.4 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.33 CDS27639.1 - 0.032 14.1 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cnd3 PF12719.7 CDS27640.1 - 1.1e-57 195.5 0.4 1.1e-57 195.5 0.4 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CDS27640.1 - 1.1e-10 41.8 5.3 0.00053 20.3 0.2 4.5 4 0 0 4 4 4 3 HEAT repeats Cnd1 PF12717.7 CDS27640.1 - 4.2e-07 30.1 5.5 0.15 12.1 0.1 4.0 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDS27640.1 - 4.5e-06 26.5 11.0 2.7 8.5 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CDS27640.1 - 0.00047 20.6 9.7 2 9.0 0.0 4.5 4 0 0 4 4 4 3 HEAT-like repeat UVR PF02151.19 CDS27640.1 - 0.41 10.4 4.9 0.29 10.9 0.1 2.9 3 0 0 3 3 3 0 UvrB/uvrC motif Pou PF00157.17 CDS27641.1 - 6.2e-37 125.4 0.0 1.1e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDS27641.1 - 1.9e-16 59.7 0.1 4.8e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CDS27641.1 - 0.0063 16.8 0.0 0.36 11.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.11 CDS27641.1 - 0.013 15.3 0.8 0.039 13.9 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain Otopetrin PF03189.13 CDS27643.2 - 3.3e-29 102.0 21.7 6.3e-25 87.9 0.7 3.0 2 1 1 3 3 3 2 Otopetrin DUF2721 PF11026.8 CDS27643.2 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Prefoldin_2 PF01920.20 CDS27644.1 - 1.2e-14 54.1 6.6 1.5e-14 53.9 6.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.12 CDS27644.1 - 0.0016 18.5 4.7 0.002 18.2 4.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GFD1 PF17331.2 CDS27644.1 - 0.13 12.5 2.0 0.13 12.5 2.0 2.0 2 0 0 2 2 2 0 GFD1 mRNA transport factor CASP_C PF08172.12 CDS27644.1 - 0.4 10.0 0.1 0.4 10.0 0.1 2.1 1 1 0 2 2 2 0 CASP C terminal FlaC_arch PF05377.11 CDS27644.1 - 0.41 11.1 4.6 1.3 9.5 0.0 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5320 PF17253.2 CDS27644.1 - 2.7 9.1 3.5 2.4 9.3 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) TP6A_N PF04406.14 CDS27647.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 Type IIB DNA topoisomerase PUF PF00806.19 CDS27648.1 - 1.3e-66 216.7 2.3 8.7e-09 34.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PAT1 PF09770.9 CDS27648.1 - 1.2 7.3 5.3 1.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Band_7 PF01145.25 CDS27649.2 - 4.8e-42 144.0 13.5 9.9e-21 74.5 4.1 3.2 2 1 1 3 3 3 3 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDS27649.2 - 5.9e-07 29.4 0.7 0.032 13.9 0.1 2.2 2 0 0 2 2 2 2 SPFH domain-Band 7 family GP68 PF17469.2 CDS27649.2 - 0.023 15.1 2.2 9.3 6.7 0.1 3.0 3 0 0 3 3 3 0 Phage protein Gp68 PGDYG PF14083.6 CDS27649.2 - 0.023 14.9 0.7 5.8 7.2 0.0 2.3 2 0 0 2 2 2 0 PGDYG protein IBN_N PF03810.19 CDS27649.2 - 0.076 12.9 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF4830 PF16112.5 CDS27649.2 - 0.12 12.9 0.1 32 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4830) NAD_binding_11 PF14833.6 CDS27649.2 - 0.19 12.0 3.3 11 6.2 0.2 2.4 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF4795 PF16043.5 CDS27649.2 - 0.2 11.2 4.4 2.1 7.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Mobilization_B PF17511.2 CDS27649.2 - 0.36 11.2 14.5 2.3 8.6 3.0 2.3 2 0 0 2 2 2 0 Mobilization protein B Sterol_MT_C PF08498.10 CDS27649.2 - 0.59 10.5 2.5 16 5.9 0.1 2.5 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal DUF1907 PF08925.11 CDS27650.1 - 8.4e-70 235.4 0.0 1.3e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) RNA_pol_I_A49 PF06870.12 CDS27650.1 - 1.9e-42 145.5 4.5 4.2e-42 144.4 4.3 1.5 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor zf-UBR PF02207.20 CDS27651.2 - 3.6e-15 55.9 8.2 3.6e-15 55.9 8.2 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 CDS27651.2 - 0.0031 17.8 0.6 0.0031 17.8 0.6 3.6 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 CDS27651.2 - 0.0035 17.2 0.3 0.0035 17.2 0.3 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 DUF3437 PF11919.8 CDS27651.2 - 0.11 12.4 0.8 28 4.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HrpA_pilin PF09589.10 CDS27651.2 - 0.34 11.7 1.1 45 4.9 0.1 2.6 2 0 0 2 2 2 0 HrpA pilus formation protein Fibrinogen_C PF00147.18 CDS27651.2 - 2.7 7.7 6.6 33 4.2 0.1 3.6 4 0 0 4 4 4 0 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4642 PF15484.6 CDS27651.2 - 8.8 6.5 7.7 34 4.6 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) EDR1 PF14381.6 CDS27652.1 - 3.2e-47 160.9 0.1 1.3e-46 158.9 0.0 1.9 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT PF02985.22 CDS27652.1 - 0.00013 21.9 0.8 0.16 12.3 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat RICTOR_V PF14668.6 CDS27652.1 - 0.00041 20.5 1.0 0.0015 18.7 0.1 2.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 IFRD PF05004.13 CDS27652.1 - 0.0015 17.7 1.3 0.33 10.0 0.1 2.6 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 CDS27652.1 - 0.0023 18.3 0.0 1.8 9.0 0.0 3.4 4 1 0 4 4 4 2 HEAT repeats WD40 PF00400.32 CDS27653.1 - 2.2e-19 69.4 11.1 0.00062 20.5 0.3 6.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27653.1 - 0.00012 22.3 0.0 4.3 7.7 0.0 4.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_L_2 PF13656.6 CDS27654.1 - 7.4e-28 96.1 0.0 9e-28 95.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDS27654.1 - 4e-10 39.0 0.0 5.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Med7 PF05983.11 CDS27655.1 - 3.7e-39 134.8 2.3 1.4e-38 132.9 2.3 1.8 1 1 0 1 1 1 1 MED7 protein Nramp PF01566.18 CDS27656.1 - 5.7e-116 387.4 14.5 5.7e-116 387.4 14.5 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein HLH PF00010.26 CDS27657.1 - 1.4e-12 47.4 1.8 1.9e-12 47.0 1.8 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TetR_C_30 PF17939.1 CDS27657.1 - 0.13 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CDS27658.1 - 1.4e-33 116.4 2.8 2.9e-33 115.3 0.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27658.1 - 1.6e-22 80.0 0.0 1.4e-21 77.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FIVAR PF07554.13 CDS27658.1 - 0.0066 17.2 1.1 0.0066 17.2 1.1 1.8 2 0 0 2 2 2 1 FIVAR domain Pox_ser-thr_kin PF05445.11 CDS27658.1 - 0.019 14.0 0.4 0.038 13.0 0.1 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CDS27658.1 - 0.081 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_E_2 PF08112.11 CDS27658.1 - 0.71 10.2 6.4 6.6 7.1 0.5 2.7 1 1 1 2 2 2 0 ATP synthase epsilon subunit Beta-lactamase PF00144.24 CDS27660.2 - 9.6e-45 153.2 0.0 4.5e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase AhpC-TSA PF00578.21 CDS27660.2 - 8.7e-37 125.8 0.0 1.9e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDS27660.2 - 6.5e-15 55.1 0.0 2.9e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CDS27660.2 - 3.1e-13 49.3 1.6 3.3e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Peptidase_S11 PF00768.20 CDS27660.2 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Nup88 PF10168.9 CDS27661.1 - 7.1e-43 146.4 1.8 1e-40 139.3 1.8 3.2 1 1 0 1 1 1 1 Nuclear pore component AIP3 PF03915.13 CDS27661.1 - 0.24 10.4 1.3 0.39 9.8 1.3 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 RVT_1 PF00078.27 CDS27662.2 - 4.1e-29 101.7 0.0 6.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDS27662.2 - 1.2e-27 95.9 0.9 5.1e-27 93.8 0.2 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS27662.2 - 1.5e-26 92.8 0.1 3.2e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS27662.2 - 2e-20 73.1 0.0 4.6e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS27662.2 - 4.8e-17 61.8 1.2 1.2e-16 60.6 1.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS27662.2 - 0.0037 17.4 0.0 0.0084 16.3 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDS27662.2 - 0.008 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Peptidase_A17 PF05380.13 CDS27662.2 - 0.012 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Pao retrotransposon peptidase BRICHOS PF04089.14 CDS27663.1 - 0.052 13.8 0.4 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 BRICHOS domain AMP-binding PF00501.28 CDS27664.2 - 1.6e-48 165.4 0.7 6.2e-21 74.5 0.0 5.7 4 2 1 5 5 5 4 AMP-binding enzyme DMAP_binding PF06464.11 CDS27664.2 - 5.5e-16 59.4 0.4 1.1e-15 58.4 0.4 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 CDS27664.2 - 0.00028 20.8 0.3 0.00058 19.8 0.3 1.4 1 0 0 1 1 1 1 Gas vesicle protein G SCP_3 PF17844.1 CDS27664.2 - 0.019 14.8 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial SCP ortholog Peptidase_M10 PF00413.24 CDS27665.1 - 2.7e-48 163.8 1.7 4e-48 163.2 1.7 1.3 1 0 0 1 1 1 1 Matrixin Glycos_transf_4 PF00953.21 CDS27665.1 - 3.1e-34 118.2 14.0 6.5e-34 117.2 14.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 Hemopexin PF00045.19 CDS27665.1 - 1e-30 105.4 5.9 4.2e-10 39.4 2.2 4.7 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.18 CDS27665.1 - 2e-06 27.9 0.0 9.6e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M66 PF10462.9 CDS27665.1 - 0.007 15.4 0.3 0.012 14.6 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.8 CDS27665.1 - 0.048 12.3 0.0 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 CDS27665.1 - 0.089 13.3 0.3 0.17 12.4 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DEAD PF00270.29 CDS27666.1 - 2.2e-44 151.3 0.0 6.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS27666.1 - 2.3e-28 98.8 0.0 8.5e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS27666.1 - 5.4e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDS27666.1 - 0.00015 21.2 1.9 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 CDS27666.1 - 0.098 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PsbQ PF05757.11 CDS27666.1 - 0.12 12.2 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-CCHC PF00098.23 CDS27666.1 - 0.12 12.5 2.7 0.2 11.8 2.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Dynein_light PF01221.18 CDS27668.1 - 1.8e-36 124.3 0.6 2.2e-36 124.0 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 SpoIIIAH PF12685.7 CDS27668.1 - 0.046 13.5 3.0 0.056 13.3 3.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein MAAL_C PF07476.11 CDS27668.1 - 0.06 12.5 0.1 0.072 12.2 0.1 1.0 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Dynein_light PF01221.18 CDS27669.2 - 1.2e-40 137.8 1.8 1.3e-40 137.6 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS27670.1 - 1.3e-41 140.8 1.6 1.5e-41 140.6 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS27671.1 - 9.4e-43 144.4 2.0 1e-42 144.3 2.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HMG_box PF00505.19 CDS27673.1 - 2.5e-36 123.9 18.0 5.3e-18 65.2 4.8 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS27673.1 - 2.4e-30 104.9 22.7 4.8e-20 71.9 7.3 2.1 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 CDS27673.1 - 0.019 14.9 3.3 0.019 14.9 3.3 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF3767 PF12597.8 CDS27673.1 - 0.04 13.7 1.9 0.04 13.7 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3767) FTCD_C PF04961.12 CDS27673.1 - 0.57 9.9 5.6 0.33 10.7 2.2 2.0 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase SYF2 PF08231.12 CDS27673.1 - 6.7 7.1 19.7 26 5.2 19.4 2.0 1 1 0 1 1 1 0 SYF2 splicing factor PINIT PF14324.6 CDS27674.2 - 4e-27 95.3 1.3 5e-27 95.0 0.1 1.8 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 CDS27674.2 - 9.6e-20 70.1 4.8 2.2e-19 68.9 4.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CDS27674.2 - 9.1e-06 25.4 2.4 1.8e-05 24.5 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ABC_tran_CTD PF16326.5 CDS27676.1 - 0.018 15.3 8.6 1.4 9.2 0.1 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 CDS27676.1 - 0.029 14.7 1.1 0.029 14.7 1.1 2.1 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 CDS27676.1 - 0.17 11.2 2.6 0.2 10.9 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) RSS_P20 PF11757.8 CDS27676.1 - 0.29 11.6 4.8 1.5 9.3 4.8 2.0 1 1 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain DMPK_coil PF08826.10 CDS27676.1 - 0.97 9.6 7.3 3.5 7.8 2.5 3.0 2 1 0 2 2 2 0 DMPK coiled coil domain like ICA69 PF04629.14 CDS27677.1 - 2.4e-06 28.0 2.7 2.5e-06 28.0 2.1 1.3 1 1 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain Arfaptin PF06456.13 CDS27678.1 - 1.8e-74 250.1 8.1 2.9e-74 249.5 8.1 1.3 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.14 CDS27678.1 - 0.0021 18.4 6.0 0.0047 17.3 6.0 1.5 1 0 0 1 1 1 1 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.9 CDS27678.1 - 0.015 14.4 6.0 0.023 13.9 5.7 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ApoLp-III PF07464.11 CDS27678.1 - 0.035 14.2 4.0 0.6 10.2 0.8 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Pardaxin PF07425.11 CDS27678.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Pardaxin TPX2 PF06886.11 CDS27679.1 - 0.00016 21.8 31.3 0.00025 21.2 15.0 3.1 3 0 0 3 3 3 2 Targeting protein for Xklp2 (TPX2) UPF0564 PF10595.9 CDS27679.1 - 0.0019 17.3 1.2 0.0019 17.3 1.2 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0564 Lipase_GDSL_3 PF14606.6 CDS27679.1 - 0.079 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family tRNA_int_endo PF01974.17 CDS27680.1 - 2.3e-17 62.8 0.0 4.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Uds1 PF15456.6 CDS27680.1 - 1.4 9.1 5.4 0.18 12.0 1.0 1.7 2 0 0 2 2 2 0 Up-regulated During Septation Kelch_1 PF01344.25 CDS27681.1 - 1.2e-20 72.8 8.4 3.5e-14 52.1 0.1 5.1 4 2 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CDS27681.1 - 9.7e-16 57.4 2.5 2.3e-11 43.6 0.1 4.2 3 1 1 4 4 4 2 Kelch motif BTB PF00651.31 CDS27681.1 - 1.4e-13 51.1 0.0 3.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDS27681.1 - 4.3e-12 45.9 3.5 1e-07 31.8 0.1 4.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS27681.1 - 1.5e-11 44.3 0.3 2e-05 24.7 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS27681.1 - 3.3e-11 42.9 0.2 0.0008 19.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CDS27681.1 - 7.7e-08 32.0 0.3 2.9e-05 23.9 0.1 3.0 2 0 0 2 2 2 1 Kelch motif BACK PF07707.15 CDS27681.1 - 0.00072 19.6 0.6 0.0028 17.7 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Bac_surface_Ag PF01103.23 CDS27682.1 - 1.1e-23 84.3 0.0 1.4e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 CDS27682.1 - 0.09 13.4 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat Forkhead PF00250.18 CDS27683.1 - 3.8e-24 84.8 1.2 2e-23 82.4 0.1 2.3 2 0 0 2 2 2 1 Forkhead domain FOXP-CC PF16159.5 CDS27683.1 - 3.4e-18 66.0 0.3 8.7e-18 64.7 0.3 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain OrsD PF12013.8 CDS27683.1 - 6.3 7.3 6.8 5.2 7.5 0.2 3.4 4 0 0 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Cpn10 PF00166.21 CDS27685.1 - 1.2e-32 111.8 0.0 1.4e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RRM_1 PF00076.22 CDS27686.1 - 9.8e-16 57.3 0.3 1.8e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS27686.1 - 0.00012 22.1 0.1 0.0004 20.4 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 CDS27686.1 - 0.28 11.3 2.3 0.57 10.2 0.1 2.1 2 0 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 CDS27686.1 - 2.1 8.6 7.5 20 5.4 0.0 3.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter cEGF PF12662.7 CDS27687.1 - 0.019 14.9 0.2 0.019 14.9 0.2 4.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like EGF PF00008.27 CDS27687.1 - 0.032 14.5 1.9 0.032 14.5 1.9 5.5 5 1 0 5 5 5 0 EGF-like domain LapA_dom PF06305.11 CDS27687.1 - 0.26 11.1 1.2 1.7 8.5 1.7 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ELO PF01151.18 CDS27688.1 - 3e-55 187.5 21.1 3.5e-55 187.2 21.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2306 PF10067.9 CDS27688.1 - 0.0015 18.8 1.5 0.0015 18.8 1.5 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) GRIM-19 PF06212.12 CDS27688.1 - 0.11 12.5 1.9 6.5 6.7 0.0 2.9 3 0 0 3 3 3 0 GRIM-19 protein XPG_N PF00752.17 CDS27689.2 - 3e-26 91.8 0.0 6.9e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDS27689.2 - 1.5e-25 89.4 0.0 4.9e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 XPG I-region SIT PF15330.6 CDS27689.2 - 0.23 11.9 0.9 0.55 10.7 0.9 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Adenine_glyco PF03352.13 CDS27689.2 - 0.51 10.1 1.9 6 6.6 0.4 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase 2-oxoacid_dh PF00198.23 CDS27691.1 - 3.8e-77 258.9 0.0 4.7e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDS27691.1 - 2.8e-19 68.7 0.3 6.9e-19 67.5 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDS27691.1 - 7.3e-11 42.2 0.1 2.9e-10 40.3 0.1 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDS27691.1 - 0.0012 18.6 0.0 0.0042 16.9 0.0 1.9 1 1 0 1 1 1 1 Biotin-lipoyl like Endostatin PF06482.11 CDS27692.1 - 1.3e-12 47.8 0.1 1.6e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Connexin PF00029.19 CDS27694.1 - 0.07 12.9 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Connexin DUF3139 PF11337.8 CDS27694.1 - 2.7 8.7 8.6 14 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Pox_EPC_I2-L1 PF12575.8 CDS27694.1 - 4.1 7.7 6.6 0.57 10.4 0.8 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 PhaG_MnhG_YufB PF03334.14 CDS27695.1 - 0.034 14.4 1.5 0.034 14.4 1.5 1.5 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Tetraspanin PF00335.20 CDS27695.1 - 0.069 12.9 7.4 0.11 12.2 7.4 1.3 1 0 0 1 1 1 0 Tetraspanin family Claudin_2 PF13903.6 CDS27695.1 - 0.3 10.8 4.9 0.38 10.5 4.9 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction BAR PF03114.18 CDS27698.1 - 6e-16 58.8 9.8 6.6e-16 58.7 9.8 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CDS27698.1 - 5.5e-11 42.1 13.9 7.4e-11 41.7 13.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 CDS27698.1 - 0.0026 17.5 10.4 0.0038 17.0 10.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family CagD PF16567.5 CDS27698.1 - 0.016 15.0 1.6 0.024 14.4 1.6 1.4 1 0 0 1 1 1 0 Pathogenicity island component CagD Annexin PF00191.20 CDS27698.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Annexin NAD_binding_10 PF13460.6 CDS27698.1 - 0.028 14.3 0.5 0.039 13.8 0.5 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fez1 PF06818.15 CDS27698.1 - 3.9 7.9 10.3 1.2 9.6 4.2 2.0 1 1 1 2 2 2 0 Fez1 EGF_CA PF07645.15 CDS27699.1 - 4.9e-05 23.5 4.5 4.9e-05 23.5 4.5 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 CDS27699.1 - 0.012 15.9 15.9 0.073 13.4 2.7 2.6 2 0 0 2 2 2 0 EGF-like domain DUF4233 PF14017.6 CDS27699.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) cEGF PF12662.7 CDS27699.1 - 0.86 9.6 0.0 0.86 9.6 0.0 3.4 3 1 0 3 3 3 0 Complement Clr-like EGF-like TNFR_c6 PF00020.18 CDS27702.1 - 0.00041 20.7 0.3 0.00041 20.7 0.3 4.2 3 2 1 4 4 4 2 TNFR/NGFR cysteine-rich region IQ PF00612.27 CDS27703.1 - 8.3e-27 90.4 89.0 0.0002 20.9 0.6 13.6 14 0 0 14 14 14 10 IQ calmodulin-binding motif CH PF00307.31 CDS27703.1 - 4e-12 46.3 0.0 2.1e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain ASH PF15780.5 CDS27703.1 - 5.6e-08 32.9 0.1 3.2e-05 24.1 0.0 3.6 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CAMSAP_CH PF11971.8 CDS27703.1 - 0.0015 18.3 0.2 0.024 14.5 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain MAT1 PF06391.13 CDS27703.1 - 4.2 7.1 8.5 0.28 11.0 2.2 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Lipocalin PF00061.23 CDS27704.1 - 2.8e-18 66.5 4.7 3.2e-18 66.3 4.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDS27704.1 - 0.00019 21.4 2.5 0.00027 20.9 2.5 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Svs_4_5_6 PF17381.2 CDS27704.1 - 0.02 15.9 0.0 0.029 15.3 0.0 1.3 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 SDA1 PF05285.12 CDS27705.1 - 0.03 13.7 55.5 0.038 13.4 55.5 1.0 1 0 0 1 1 1 0 SDA1 SID-1_RNA_chan PF13965.6 CDS27705.1 - 0.057 11.8 1.8 0.069 11.6 1.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BUD22 PF09073.10 CDS27705.1 - 0.15 11.4 39.8 0.17 11.2 39.8 1.0 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 CDS27705.1 - 0.67 8.3 45.1 0.92 7.9 45.1 1.2 1 0 0 1 1 1 0 Mpp10 protein V_ATPase_I PF01496.19 CDS27705.1 - 2.1 6.2 20.0 9.1 4.0 20.0 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4045 PF13254.6 CDS27705.1 - 2.4 7.7 14.9 2.8 7.5 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PA26 PF04636.13 CDS27705.1 - 2.5 6.9 10.0 2.8 6.7 10.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Spore_coat_CotO PF14153.6 CDS27705.1 - 6.3 6.7 26.5 9.7 6.1 26.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CCSAP PF15748.5 CDS27705.1 - 6.9 6.8 21.2 8.4 6.5 21.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated HECT PF00632.25 CDS27706.2 - 1e-27 97.5 0.1 2.4e-27 96.2 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 CDS27706.2 - 0.00011 22.7 0.0 0.00053 20.5 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27706.2 - 0.0036 17.9 0.2 3.1 8.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NADH-UOR_E PF16514.5 CDS27706.2 - 0.028 14.7 0.3 0.11 12.8 0.3 2.1 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E Lipocalin PF00061.23 CDS27708.1 - 1.6e-17 64.1 3.9 1.8e-17 63.9 3.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDS27708.1 - 1.9e-05 24.6 2.2 6.8e-05 22.8 0.3 1.9 1 1 1 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDS27709.1 - 6.4e-05 22.9 0.3 0.00011 22.1 0.3 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Cupredoxin_1 PF13473.6 CDS27709.1 - 0.0018 18.4 0.1 0.0057 16.8 0.0 1.7 2 0 0 2 2 2 1 Cupredoxin-like domain DUF4869 PF16163.5 CDS27709.1 - 0.037 13.7 0.3 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) Triabin PF03973.13 CDS27709.1 - 0.077 12.9 0.3 0.12 12.2 0.3 1.4 1 1 0 1 1 1 0 Triabin Lipocalin PF00061.23 CDS27711.1 - 3.6e-15 56.4 1.3 4e-15 56.3 1.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDS27711.1 - 0.00018 21.4 0.5 0.00023 21.1 0.5 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family FG-GAP PF01839.23 CDS27712.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 FG-GAP repeat Itfg2 PF15907.5 CDS27712.1 - 0.13 11.2 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Tubulin PF00091.25 CDS27713.1 - 2.6e-59 200.8 0.0 3.7e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS27713.1 - 2.5e-51 173.1 0.0 4e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS27713.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 CDS27714.1 - 2.8e-37 126.4 3.4 5e-18 64.7 0.3 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F5_F8_type_C PF00754.25 CDS27715.1 - 6.3e-15 55.4 0.0 2.1e-13 50.5 0.0 2.7 2 0 0 2 2 2 1 F5/8 type C domain Methyltransf_11 PF08241.12 CDS27717.1 - 4.2e-10 40.1 0.0 6.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS27717.1 - 5.3e-06 27.0 0.0 8.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS27717.1 - 0.00042 20.2 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDS27717.1 - 0.0097 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 CDS27717.1 - 0.015 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Inhibitor_I78 PF11720.8 CDS27717.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Ufd2P_core PF10408.9 CDS27718.1 - 5.2e-99 332.6 0.0 8.1e-99 331.9 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CDS27718.1 - 8.5e-28 96.3 0.7 2.2e-27 95.0 0.7 1.8 1 0 0 1 1 1 1 U-box domain DUF1279 PF06916.13 CDS27720.1 - 1.6e-14 54.2 1.2 2.8e-14 53.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1279 PF06916.13 CDS27721.1 - 1.6e-05 25.4 0.1 2.2e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) eIF-1a PF01176.19 CDS27722.1 - 2.4e-22 78.5 0.1 3.7e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NOA36 PF06524.12 CDS27722.1 - 0.13 11.6 4.8 0.18 11.1 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 CDS27722.1 - 0.3 10.2 6.9 0.38 9.8 6.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 CDS27722.1 - 6.5 5.2 5.5 8.5 4.8 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LRR_8 PF13855.6 CDS27723.1 - 2.5e-19 68.8 34.8 1.1e-08 34.7 3.1 4.5 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CDS27723.1 - 1.7e-12 47.3 43.7 0.0001 22.6 5.4 5.2 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS27723.1 - 0.00011 22.3 38.0 0.015 15.7 1.5 8.1 7 2 1 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 CDS27723.1 - 0.00017 21.3 31.5 1.1 9.5 0.0 7.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 CDS27723.1 - 0.16 11.4 13.7 0.079 12.5 1.3 2.4 1 1 0 2 2 2 0 Leucine-rich repeat Prefoldin_2 PF01920.20 CDS27724.2 - 3.2e-16 59.2 3.1 3.2e-16 59.2 3.1 2.2 3 0 0 3 3 3 1 Prefoldin subunit Cir_N PF10197.9 CDS27724.2 - 1.9e-11 44.0 3.9 6.9e-11 42.1 3.9 2.1 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 CDS27724.2 - 0.014 15.2 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Med15_fungi PF05397.12 CDS27724.2 - 0.046 14.0 3.0 0.56 10.5 0.9 2.4 2 0 0 2 2 2 0 Mediator complex subunit 15 ABC_membrane PF00664.23 CDS27727.2 - 2.4e-90 302.9 21.1 1.2e-46 159.6 3.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDS27727.2 - 2.6e-69 232.0 0.5 3e-34 118.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CDS27727.2 - 1.2e-14 54.3 3.4 6.6e-05 22.5 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDS27727.2 - 1.6e-09 38.4 4.0 0.00068 20.1 0.3 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CDS27727.2 - 2.2e-09 37.7 0.8 0.0052 17.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDS27727.2 - 2.5e-07 30.3 1.0 0.0051 16.5 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CDS27727.2 - 4.3e-07 30.0 0.0 0.069 13.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CDS27727.2 - 6.4e-07 28.9 0.2 0.039 13.2 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 CDS27727.2 - 1.5e-06 28.2 0.4 0.057 13.3 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 CDS27727.2 - 2.2e-06 26.8 0.9 0.093 11.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 CDS27727.2 - 3.2e-06 27.0 5.6 0.017 14.9 1.0 3.9 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 CDS27727.2 - 1.1e-05 24.8 0.1 0.034 13.3 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 CDS27727.2 - 1.5e-05 24.6 0.2 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 CDS27727.2 - 9.5e-05 22.3 0.0 0.68 9.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CDS27727.2 - 0.00013 22.1 5.5 0.41 10.9 0.2 4.3 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDS27727.2 - 0.00018 22.1 0.0 0.67 10.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDS27727.2 - 0.00023 21.2 0.1 0.83 9.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDS27727.2 - 0.00035 20.3 0.3 0.23 11.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CDS27727.2 - 0.0005 20.5 1.1 1 9.8 0.0 4.4 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CDS27727.2 - 0.00073 19.2 2.6 4.8 6.7 0.1 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CDS27727.2 - 0.0011 19.3 0.0 1.6 9.0 0.0 3.6 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 CDS27727.2 - 0.0016 18.3 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 CDS27727.2 - 0.0032 17.4 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 CDS27727.2 - 0.0041 17.2 1.6 0.3 11.1 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_17 PF13207.6 CDS27727.2 - 0.0043 17.5 0.0 5.1 7.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 CDS27727.2 - 0.0048 16.6 6.0 0.32 10.6 4.1 3.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CDS27727.2 - 0.0049 16.9 0.1 5.1 7.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 CDS27727.2 - 0.0057 15.9 0.3 2.5 7.2 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.6 CDS27727.2 - 0.0074 16.4 0.0 3.8 7.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CDS27727.2 - 0.008 16.0 2.1 5.2 6.8 0.3 3.5 2 2 0 2 2 2 0 DEAD/DEAH box helicase APS_kinase PF01583.20 CDS27727.2 - 0.012 15.5 0.2 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PTPS_related PF10131.9 CDS27727.2 - 0.018 13.4 0.5 0.044 12.1 0.5 1.6 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Sigma54_activat PF00158.26 CDS27727.2 - 0.024 14.3 0.1 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3894 PF13033.6 CDS27727.2 - 0.025 14.7 2.1 0.1 12.7 1.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3894) Rad17 PF03215.15 CDS27727.2 - 0.025 14.5 0.3 3.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 CDS27727.2 - 0.043 14.2 0.0 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 CDS27727.2 - 0.045 13.5 0.0 9.9 5.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CDS27727.2 - 0.056 12.8 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CDS27727.2 - 0.057 13.9 4.3 4 7.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain DUF3987 PF13148.6 CDS27727.2 - 0.084 11.9 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) GMC_oxred_N PF00732.19 CDS27727.2 - 0.085 12.2 0.2 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase Se-cys_synth_N PF12390.8 CDS27727.2 - 0.12 12.7 0.1 0.39 11.0 0.1 1.9 1 0 0 1 1 1 0 Selenocysteine synthase N terminal IstB_IS21 PF01695.17 CDS27727.2 - 0.14 11.8 2.5 11 5.7 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein MoaE PF02391.17 CDS27727.2 - 0.15 12.4 0.8 8.7 6.7 0.1 2.9 2 0 0 2 2 2 0 MoaE protein ATP_bind_1 PF03029.17 CDS27727.2 - 0.19 11.5 1.5 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NFRKB_winged PF14465.6 CDS27728.1 - 3.4e-09 36.8 0.2 8.4e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 NFRKB Winged Helix-like RRM_1 PF00076.22 CDS27729.1 - 1.9e-38 130.1 0.4 1.1e-18 66.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 CDS27729.1 - 2e-09 36.6 1.7 4.9e-09 35.4 1.7 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_Rrp7 PF17799.1 CDS27729.1 - 0.00071 19.4 0.1 0.018 14.8 0.0 2.9 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 CDS27729.1 - 0.00093 19.0 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RP-C_C PF11800.8 CDS27729.1 - 0.0054 16.9 2.7 0.0054 16.9 2.7 2.7 3 0 0 3 3 3 1 Replication protein C C-terminal region RRM_3 PF08777.11 CDS27729.1 - 0.006 16.6 2.2 0.41 10.7 0.1 3.7 3 0 0 3 3 3 1 RNA binding motif LSM_int_assoc PF16605.5 CDS27729.1 - 0.012 15.7 1.2 0.034 14.2 1.2 1.8 1 0 0 1 1 1 0 LSM-interacting associated unstructured Nup35_RRM_2 PF14605.6 CDS27729.1 - 0.015 15.3 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RUN PF02759.19 CDS27730.1 - 3.4e-30 104.8 0.2 4.8e-19 68.7 0.8 3.9 2 2 0 2 2 2 2 RUN domain DENN PF02141.21 CDS27730.1 - 4.8e-14 52.7 0.5 1.3e-13 51.3 0.2 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 CDS27730.1 - 3.2e-10 39.8 1.2 6.4e-10 38.9 0.1 2.2 2 0 0 2 2 2 1 dDENN domain PLAT PF01477.23 CDS27730.1 - 7.5e-08 32.9 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain DENN PF02141.21 CDS27731.1 - 3.1e-12 46.8 0.0 9.5e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CDS27731.1 - 5.9e-06 26.9 0.1 2.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 uDENN domain KH_8 PF17903.1 CDS27732.1 - 9.8e-31 105.7 0.2 3.8e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 CDS27732.1 - 0.021 14.6 0.3 0.042 13.7 0.3 1.5 1 0 0 1 1 1 0 KH domain NfeD PF01957.18 CDS27732.1 - 0.084 13.3 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Glyco_hydro_67N PF03648.14 CDS27732.1 - 0.092 13.0 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus Iwr1 PF08574.10 CDS27733.1 - 0.00026 21.9 20.9 0.00026 21.9 20.9 3.9 2 1 1 3 3 3 1 Transcription factor Iwr1 Humanin PF15040.6 CDS27733.1 - 0.83 9.2 3.7 3.4 7.2 0.2 2.9 3 0 0 3 3 3 0 Humanin family BUD22 PF09073.10 CDS27733.1 - 7.5 5.8 9.1 8.9 5.5 9.1 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 CDS27735.1 - 1.4e-56 191.8 0.0 4e-30 105.1 0.3 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27735.1 - 3.8e-29 101.8 0.0 3.1e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS27735.1 - 0.0036 16.7 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDS27735.1 - 0.0096 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS27735.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Bromodomain PF00439.25 CDS27736.2 - 2.3e-27 94.8 1.0 9.8e-13 48.0 0.0 2.7 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.32 CDS27736.2 - 3.9e-05 24.3 8.9 0.041 14.7 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PMM PF03332.13 CDS27737.1 - 2.5e-101 338.1 1.2 2.8e-101 337.9 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CDS27737.1 - 1.7e-06 27.9 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDS27737.1 - 0.053 13.8 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 CDS27737.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase DUF3546 PF12066.8 CDS27738.2 - 3.7e-37 126.9 2.7 1.1e-36 125.3 2.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 CDS27738.2 - 1.8e-34 119.8 2.9 1.9e-34 119.7 0.1 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF641 PF04859.12 CDS27739.1 - 0.022 15.1 1.8 0.066 13.6 1.8 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Nup54 PF13874.6 CDS27739.1 - 0.047 13.8 0.5 0.047 13.8 0.5 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 MetOD2 PF18548.1 CDS27739.1 - 0.12 12.5 0.8 0.45 10.7 0.8 1.9 1 0 0 1 1 1 0 Metanogen output domain 2 Exonuc_VII_L PF02601.15 CDS27739.1 - 0.21 11.1 0.5 0.33 10.5 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V-SNARE PF05008.15 CDS27739.1 - 0.26 11.7 4.9 0.077 13.4 1.6 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Cep57_CLD_2 PF14197.6 CDS27739.1 - 0.79 9.9 5.9 2.2 8.4 5.9 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HIP1_clath_bdg PF16515.5 CDS27739.1 - 5 7.8 6.7 2.2 8.9 2.7 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L3 PF00297.22 CDS27740.1 - 6.6e-17 61.5 0.2 3.6e-15 55.8 0.6 2.7 2 1 1 3 3 3 1 Ribosomal protein L3 Histone PF00125.24 CDS27740.1 - 3.7e-16 59.7 0.0 6.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDS27740.1 - 2e-11 43.4 0.6 3.4e-11 42.7 0.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDS27740.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Noggin PF05806.12 CDS27741.1 - 3.7e-29 102.2 6.8 6e-29 101.5 6.8 1.4 1 1 0 1 1 1 1 Noggin Pkinase PF00069.25 CDS27742.1 - 1.6e-69 234.2 0.0 1.9e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27742.1 - 9.5e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS27742.1 - 5.6e-05 22.6 0.2 0.00017 21.0 0.1 1.8 1 1 0 2 2 2 1 Kinase-like Guanylate_cyc PF00211.20 CDS27743.1 - 9.8e-66 220.9 0.0 1.6e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDS27743.1 - 1.1e-31 110.1 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS27743.1 - 6.2e-26 91.3 0.0 1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CDS27743.1 - 1.1e-05 24.9 0.4 1.9e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 Heme NO binding associated HTH_48 PF17906.1 CDS27743.1 - 0.00033 20.7 0.2 0.00088 19.3 0.2 1.8 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Actin PF00022.19 CDS27744.1 - 4.6e-50 170.4 0.0 1.7e-27 96.1 0.0 3.0 1 1 2 3 3 3 3 Actin WD40 PF00400.32 CDS27746.1 - 1.6 9.7 5.6 4 8.5 0.4 3.4 3 1 0 3 3 3 0 WD domain, G-beta repeat SH3_2 PF07653.17 CDS27748.1 - 0.033 13.9 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DHHC PF01529.20 CDS27748.1 - 0.048 13.8 0.4 0.082 13.0 0.4 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase PLAC8 PF04749.17 CDS27748.1 - 2 9.5 6.2 4e+02 2.1 6.2 3.3 1 1 0 1 1 1 0 PLAC8 family Cadherin PF00028.17 CDS27749.1 - 7.1e-30 103.3 0.0 2.2e-08 34.4 0.0 6.4 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CDS27749.1 - 3.2e-13 49.3 0.0 1.8e-11 43.7 0.0 3.3 4 0 0 4 4 4 1 Cadherin-like CAF1 PF04857.20 CDS27750.1 - 3.2e-18 66.0 8.3 8.4e-14 51.5 0.1 3.0 1 1 1 2 2 2 2 CAF1 family ribonuclease Topoisom_I PF01028.20 CDS27751.1 - 8.7e-101 336.0 5.8 8.7e-101 336.0 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CDS27751.1 - 2.1e-99 331.3 6.2 2.1e-99 331.3 6.2 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CDS27751.1 - 2.9e-32 110.4 1.2 1.2e-31 108.4 1.2 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Gemin7 PF11095.8 CDS27751.1 - 0.051 13.5 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Melibiase_2_C PF17450.2 CDS27751.1 - 0.11 12.8 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Cep57_MT_bd PF06657.13 CDS27751.1 - 0.51 10.8 5.7 1.4 9.4 0.0 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.6 CDS27751.1 - 5.7 7.4 16.5 0.35 11.3 8.2 3.1 2 1 1 3 3 3 0 Syntaxin-like protein GSH_synth_ATP PF03917.17 CDS27752.1 - 2.3e-104 349.2 0.0 2.7e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDS27752.1 - 3.1e-27 95.0 0.0 5.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ribosomal_L3 PF00297.22 CDS27753.1 - 1.2e-175 583.9 12.8 5.2e-175 581.8 12.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 CDS27754.2 - 1.6e-66 224.8 2.0 2e-56 191.6 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 E1-E2_ATPase PF00122.20 CDS27755.1 - 3.4e-06 26.7 0.0 3.4e-06 26.7 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase DUF1415 PF07209.12 CDS27755.1 - 0.14 11.9 0.1 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Cyt-b5 PF00173.28 CDS27756.1 - 9.7e-23 80.1 0.0 1.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDCD9 PF07147.12 CDS27757.1 - 0.00049 19.4 0.3 0.001 18.4 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DnaJ PF00226.31 CDS27758.1 - 4.1e-21 74.9 0.1 7.5e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Saf_2TM PF18303.1 CDS27758.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Josephin PF02099.17 CDS27759.1 - 4.3e-20 72.5 0.1 5.9e-19 68.7 0.1 2.0 1 1 0 1 1 1 1 Josephin SET PF00856.28 CDS27760.1 - 2.3e-12 47.6 0.1 1.3e-11 45.1 0.1 2.2 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 CDS27760.1 - 2.9e-08 33.2 6.2 2.6e-05 23.8 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27760.1 - 7.4e-06 25.7 6.2 8.5e-05 22.4 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS27760.1 - 8.9e-06 26.1 0.2 4.2e-05 24.0 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS27760.1 - 0.0016 18.5 1.2 0.12 12.5 0.1 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CDS27760.1 - 0.0066 16.7 0.5 0.0066 16.7 0.5 2.1 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CDS27760.1 - 0.015 15.0 0.4 0.083 12.6 0.2 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 CDS27760.1 - 0.018 15.7 0.0 0.048 14.3 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDS27760.1 - 0.019 14.4 0.0 0.079 12.4 0.0 2.0 2 0 0 2 2 2 0 SHNi-TPR TPR_12 PF13424.6 CDS27760.1 - 0.025 14.9 1.7 0.044 14.1 0.1 2.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS27760.1 - 0.034 14.2 0.1 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS27760.1 - 0.048 13.9 5.2 0.23 11.8 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CaKB PF03185.15 CDS27761.1 - 8.3e-10 38.7 8.2 4.4e-05 23.2 0.0 3.2 3 0 0 3 3 3 3 Calcium-activated potassium channel, beta subunit Diphthami_syn_2 PF01902.17 CDS27762.1 - 1.5e-25 90.0 0.0 3.2e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Diphthamide synthase Cation_efflux PF01545.21 CDS27762.1 - 2.8e-25 89.2 7.8 4.3e-25 88.6 7.8 1.3 1 0 0 1 1 1 1 Cation efflux family mTERF PF02536.14 CDS27762.1 - 1.2e-10 40.8 1.3 7.7e-06 25.0 0.2 2.1 1 1 1 2 2 2 2 mTERF Tmemb_14 PF03647.13 CDS27762.1 - 0.18 12.6 7.0 5.4 7.8 0.3 2.6 2 0 0 2 2 2 0 Transmembrane proteins 14C Put_DNA-bind_N PF06971.13 CDS27763.1 - 0.067 13.2 3.6 6.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus TFIIA PF03153.13 CDS27763.1 - 0.75 9.7 27.2 0.92 9.4 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.22 CDS27765.1 - 1.1e-57 194.1 0.1 1.3e-57 193.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS27765.1 - 6.1e-29 100.7 0.0 9.6e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS27765.1 - 6.4e-13 48.5 0.1 9.3e-13 48.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS27765.1 - 0.00081 19.0 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS27765.1 - 0.0038 17.3 0.0 0.0073 16.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDS27765.1 - 0.0088 15.4 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDS27765.1 - 0.02 14.8 0.1 0.31 10.9 0.1 2.3 1 1 0 2 2 2 0 RsgA GTPase TetR_C_16 PF17920.1 CDS27765.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AMP-binding PF00501.28 CDS27766.1 - 3.5e-94 315.8 0.0 4.2e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDS27766.1 - 0.015 16.3 0.0 0.04 14.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DHHC PF01529.20 CDS27767.1 - 1.2e-32 112.8 23.2 6.6e-32 110.4 13.8 3.0 2 1 1 3 3 3 2 DHHC palmitoyltransferase DUF2178 PF09946.9 CDS27767.1 - 2.6 8.3 6.0 0.72 10.1 0.7 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2178) PI3_PI4_kinase PF00454.27 CDS27768.1 - 2.8e-49 168.2 0.0 5.8e-49 167.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CDS27768.1 - 4.5e-17 62.3 2.2 8.4e-17 61.4 2.2 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CDS27768.1 - 4.2e-15 55.3 0.0 1.7e-14 53.3 0.0 2.2 1 0 0 1 1 1 1 FATC domain UME PF08064.13 CDS27768.1 - 7e-14 51.6 0.2 4.2e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain DUF3385 PF11865.8 CDS27768.1 - 0.01 15.7 0.0 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) TPR_14 PF13428.6 CDS27768.1 - 0.31 12.0 4.9 61 4.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Transposase_1 PF01359.18 CDS27771.1 - 4.6e-07 29.6 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Rhomboid PF01694.22 CDS27776.1 - 1.3e-28 99.9 11.5 1.3e-28 99.9 11.5 1.9 1 1 0 1 1 1 1 Rhomboid family Adipogenin PF15202.6 CDS27776.1 - 0.11 12.5 3.6 0.21 11.6 3.6 1.4 1 0 0 1 1 1 0 Adipogenin EF-hand_5 PF13202.6 CDS27776.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 EF hand ECF_trnsprt PF12822.7 CDS27776.1 - 6 6.9 10.3 7.2 6.7 5.4 2.5 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF1664 PF07889.12 CDS27777.2 - 0.73 9.9 8.2 2.5 8.2 0.3 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Thioredoxin PF00085.20 CDS27779.1 - 6e-17 61.5 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CDS27779.1 - 4.8e-05 23.4 0.2 0.0013 18.7 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDS27779.1 - 0.00055 20.1 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Fibrinogen_aC PF12160.8 CDS27779.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain Metallophos PF00149.28 CDS27780.1 - 3e-13 50.8 0.1 5e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NS3_envE PF02723.14 CDS27780.1 - 0.022 14.8 0.4 0.048 13.7 0.4 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E ATP-synt_A PF00119.20 CDS27780.1 - 0.13 12.1 0.9 0.4 10.6 0.0 2.1 3 0 0 3 3 3 0 ATP synthase A chain Cyclin_N PF00134.23 CDS27781.1 - 3.5e-17 62.3 0.2 5.8e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS27782.1 - 0.0017 18.4 0.1 0.0035 17.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CDS27783.1 - 3.1e-05 23.7 0.1 6.3e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS27783.1 - 0.00021 21.4 1.0 0.00087 19.4 1.0 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CDS27784.1 - 6.2e-16 58.3 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS27784.1 - 2.7e-07 30.7 0.2 7.1e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Myb_Cef PF11831.8 CDS27785.1 - 2.2e-60 204.2 6.4 2.2e-60 204.2 6.4 3.9 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CDS27785.1 - 7.1e-22 77.3 6.4 7.6e-12 45.2 1.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS27785.1 - 4e-20 71.8 7.4 8.7e-13 48.3 3.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Endosulfine PF04667.17 CDS27785.1 - 0.038 14.1 2.1 0.16 12.1 0.1 3.1 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region Rap1_C PF11626.8 CDS27785.1 - 0.17 12.0 4.0 0.23 11.6 0.3 3.0 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TTC5_OB PF16669.5 CDS27787.1 - 3.7e-41 139.4 0.0 5.6e-41 138.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_11 PF13414.6 CDS27787.1 - 1.5e-07 31.0 0.0 0.0021 17.7 0.1 3.7 4 0 0 4 4 4 2 TPR repeat FAT PF02259.23 CDS27787.1 - 0.035 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 FAT domain Coatomer_E PF04733.14 CDS27787.1 - 0.036 13.5 0.1 0.21 11.0 0.0 2.0 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_1 PF00515.28 CDS27787.1 - 0.21 11.4 2.4 71 3.5 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27787.1 - 0.98 9.7 3.4 32 5.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CDS27788.1 - 3.3e-67 226.7 0.0 4.7e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27788.1 - 4.5e-35 121.2 0.0 6.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS27788.1 - 1.6e-05 24.0 0.1 2.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS27788.1 - 6.8e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS27788.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M1 PF01433.20 CDS27790.1 - 2.1e-85 285.7 2.1 3.4e-85 285.0 2.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDS27790.1 - 8.7e-74 248.9 0.0 1.3e-73 248.3 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDS27790.1 - 2.6e-43 148.4 0.6 8e-43 146.8 0.6 1.9 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 CDS27790.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF2518 PF10726.9 CDS27790.1 - 0.12 12.0 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of function (DUF2518) Tim17 PF02466.19 CDS27790.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family NYD-SP28 PF14772.6 CDS27791.1 - 0.15 12.1 3.3 0.36 10.9 1.6 2.5 2 0 0 2 2 2 0 Sperm tail 7tm_2 PF00002.24 CDS27793.1 - 6.5e-08 32.2 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ribosomal_S27e PF01667.17 CDS27794.1 - 8e-23 79.9 1.0 1.6e-22 79.0 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 Stevor PF17410.2 CDS27794.1 - 0.0072 15.9 0.4 0.011 15.3 0.4 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame MLANA PF14991.6 CDS27794.1 - 0.054 13.8 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein melan-A Syndecan PF01034.20 CDS27794.1 - 0.14 12.1 3.4 0.28 11.1 3.4 1.4 1 0 0 1 1 1 0 Syndecan domain Ashwin PF15323.6 CDS27795.1 - 4.1e-06 27.0 4.0 7.2e-06 26.2 4.0 1.5 1 1 0 1 1 1 1 Developmental protein WD40 PF00400.32 CDS27796.2 - 5.7e-26 90.3 1.3 1.9e-06 28.5 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27796.2 - 2.7e-09 37.2 0.0 0.44 10.9 0.1 5.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS27796.2 - 1.5e-06 28.2 0.5 0.0021 18.0 0.1 3.6 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDS27796.2 - 5e-05 22.4 0.1 0.38 9.7 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDS27796.2 - 0.005 16.2 0.7 0.45 9.8 0.1 3.2 4 0 0 4 4 4 1 WD40-like domain DUF2415 PF10313.9 CDS27796.2 - 0.05 13.5 0.1 0.47 10.4 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised protein domain (DUF2415) COesterase PF00135.28 CDS27797.1 - 9.7e-136 453.6 0.0 1.2e-135 453.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS27797.1 - 3.6e-10 40.1 0.1 9.5e-10 38.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold GAS PF13851.6 CDS27798.2 - 6.3e-06 25.7 16.0 6.3e-06 25.7 16.0 13.1 6 3 5 13 13 13 5 Growth-arrest specific micro-tubule binding GPS2_interact PF15784.5 CDS27798.2 - 0.00033 21.0 2.7 0.00033 21.0 2.7 10.7 8 4 3 12 12 12 1 G-protein pathway suppressor 2-interacting domain ATG16 PF08614.11 CDS27798.2 - 0.0011 19.3 0.7 0.0011 19.3 0.7 13.8 4 2 7 13 13 13 3 Autophagy protein 16 (ATG16) SOGA PF11365.8 CDS27798.2 - 0.0041 18.2 12.0 0.0041 18.2 12.0 15.5 8 5 6 15 15 15 1 Protein SOGA Vip3A_N PF12495.8 CDS27798.2 - 1.3 8.9 8.9 12 5.7 1.0 4.0 4 0 0 4 4 4 0 Vegetative insecticide protein 3A N terminal Porin_3 PF01459.22 CDS27799.1 - 7.5e-33 114.1 0.5 8.7e-33 113.9 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Peptidase_S9 PF00326.21 CDS27800.1 - 3.2e-46 157.5 0.0 4.9e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CDS27800.1 - 3.3e-46 157.7 0.0 4.8e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Hydrolase_4 PF12146.8 CDS27800.1 - 0.0032 16.8 0.0 0.22 10.7 0.0 2.8 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDS27800.1 - 0.0063 17.1 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.12 CDS27800.1 - 0.027 14.4 0.6 0.11 12.5 0.6 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DLH PF01738.18 CDS27800.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Yippee-Mis18 PF03226.14 CDS27801.1 - 0.0034 17.6 0.3 2.6 8.3 0.0 2.7 3 0 0 3 3 3 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CDS27801.1 - 0.03 14.5 0.2 12 6.2 0.0 2.7 3 0 0 3 3 3 0 C-terminal domain of RIG-I HECT_2 PF09814.9 CDS27801.1 - 0.06 12.2 0.6 2 7.2 0.0 2.1 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Jas PF16135.5 CDS27801.1 - 0.09 13.0 0.0 2 8.6 0.0 2.7 3 0 0 3 3 3 0 TPL-binding domain in jasmonate signalling GHMP_kinases_C PF08544.13 CDS27805.1 - 7.6e-05 23.0 0.1 9.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 GHMP kinases C terminal VirJ PF06057.11 CDS27805.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Actin PF00022.19 CDS27806.1 - 5.8e-87 291.9 0.0 2.9e-53 180.9 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 CDS27806.1 - 1.6e-07 30.5 0.0 0.0007 18.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CDS27806.1 - 0.00019 21.8 0.0 0.0004 20.7 0.0 1.6 2 0 0 2 2 2 1 Cell division protein FtsA PEPCK_GTP PF00821.18 CDS27807.1 - 3.3e-156 519.6 0.1 4e-156 519.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 CDS27807.1 - 5.9e-92 307.2 0.0 7.9e-92 306.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Zw10 PF06248.13 CDS27808.1 - 8.3e-15 54.3 11.9 5.3e-14 51.7 0.7 3.1 3 0 0 3 3 3 3 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.12 CDS27808.1 - 0.2 11.7 2.4 6.8 6.7 0.1 3.9 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2228 PF10228.9 CDS27809.1 - 2.9e-40 138.6 0.3 3.4e-24 85.9 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2228) Trypsin PF00089.26 CDS27810.1 - 3.1e-34 118.7 0.0 5.6e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDS27810.1 - 0.0059 17.0 0.4 0.052 13.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CDS27810.1 - 0.021 15.7 0.0 0.046 14.6 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain FAM176 PF14851.6 CDS27812.1 - 0.052 13.2 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Saf_2TM PF18303.1 CDS27812.1 - 1.2 8.7 3.7 8.7 5.9 0.0 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain MYO10_CC PF16735.5 CDS27813.1 - 0.025 14.7 0.2 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Abhydrolase_1 PF00561.20 CDS27814.1 - 5.2e-11 42.7 0.0 1.7e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS27814.1 - 6.6e-10 38.7 0.0 2e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDS27814.1 - 0.014 16.0 0.0 0.021 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDS27815.2 - 5.2e-11 42.7 0.0 1.2e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS27815.2 - 7.8e-11 41.7 0.0 2.2e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 MBOAT PF03062.19 CDS27816.1 - 3.9e-20 72.5 15.0 3.9e-20 72.5 15.0 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CBS PF00571.28 CDS27817.2 - 6.8e-09 36.0 0.0 0.00098 19.5 0.0 3.9 4 0 0 4 4 4 3 CBS domain tRNA-synt_1 PF00133.22 CDS27818.1 - 4.1e-224 745.3 0.0 5.2e-224 745.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDS27818.1 - 4.4e-21 75.4 0.4 9.1e-21 74.4 0.1 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDS27818.1 - 1.2e-13 50.6 0.2 0.00032 19.5 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDS27818.1 - 0.0036 16.7 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Peptidase_M48 PF01435.18 CDS27823.1 - 0.00068 19.5 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Spore_GerAC PF05504.11 CDS27824.1 - 0.041 14.1 0.1 0.046 14.0 0.1 1.0 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Peptidase_M48 PF01435.18 CDS27828.1 - 2.7e-08 33.8 1.2 5.7e-07 29.5 1.2 2.0 1 1 0 1 1 1 1 Peptidase family M48 Nup35_RRM PF05172.13 CDS27828.1 - 0.18 11.8 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SCF PF02404.15 CDS27833.1 - 0.0087 15.4 0.2 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 Stem cell factor PIF1 PF05970.14 CDS27835.1 - 1.9e-47 162.2 0.6 2.4e-45 155.3 0.6 2.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDS27835.1 - 5.4e-16 58.9 0.0 9.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS27835.1 - 4.6e-07 30.3 0.0 9.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDS27835.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 CDS27835.1 - 0.0018 17.7 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CDS27835.1 - 0.0034 17.2 1.2 1.1 8.9 0.3 3.4 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CDS27835.1 - 0.0051 14.8 0.1 0.018 13.0 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 CDS27835.1 - 0.012 15.9 0.2 0.037 14.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS27835.1 - 0.033 13.7 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CDS27835.1 - 0.061 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 CDS27835.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Tax PF02959.16 CDS27835.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 HTLV Tax T2SSE PF00437.20 CDS27835.1 - 0.15 11.1 0.1 0.42 9.6 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Acetyltransf_1 PF00583.25 CDS27836.1 - 2.6e-16 59.9 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDS27836.1 - 6.7e-12 45.4 0.0 8.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDS27836.1 - 6e-09 36.2 0.2 1e-08 35.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDS27836.1 - 3.2e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDS27836.1 - 0.00067 20.3 0.0 0.00092 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDS27836.1 - 0.009 16.1 0.1 0.012 15.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CDS27836.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.4 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 CDS27836.1 - 0.036 14.0 0.2 0.071 13.1 0.2 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TMEM219 PF14940.6 CDS27838.1 - 8.6e-21 74.6 0.1 8.6e-21 74.6 0.1 1.4 2 0 0 2 2 2 1 Transmembrane 219 WD40 PF00400.32 CDS27839.1 - 7.1e-40 134.3 17.5 8.1e-05 23.3 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 CDS27839.1 - 1.4e-13 50.1 2.6 2.8e-13 49.1 2.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CDS27839.1 - 4.8e-10 39.6 0.0 0.091 13.1 0.0 5.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS27839.1 - 8.7e-05 21.6 0.3 0.089 11.7 0.0 4.5 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDS27839.1 - 0.00023 20.0 1.8 7.2 5.1 0.1 4.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 FlgN PF05130.12 CDS27839.1 - 0.11 13.0 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 FlgN protein Forkhead PF00250.18 CDS27840.2 - 1e-20 73.8 0.7 2e-20 72.8 0.7 1.5 1 0 0 1 1 1 1 Forkhead domain LOH1CR12 PF10158.9 CDS27840.2 - 0.053 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor protein AhpC-TSA PF00578.21 CDS27843.1 - 1.1e-39 135.2 0.0 1.5e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDS27843.1 - 2.7e-20 72.6 0.0 3.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDS27843.1 - 7e-14 51.4 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CDS27843.1 - 0.029 14.3 0.6 0.049 13.5 0.1 1.6 2 0 0 2 2 2 0 SCO1/SenC Vault PF01505.18 CDS27843.1 - 0.16 12.1 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Major Vault Protein repeat domain AhpC-TSA PF00578.21 CDS27844.2 - 1.3e-38 131.7 0.0 1.8e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDS27844.2 - 2.1e-16 60.0 0.0 2.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDS27844.2 - 4.9e-11 42.3 0.0 9.9e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CDS27844.2 - 0.011 15.7 0.2 0.024 14.5 0.1 1.6 2 0 0 2 2 2 0 SCO1/SenC DUF4807 PF16065.5 CDS27846.2 - 8.8e-41 138.5 0.1 1.3e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) TPR_4 PF07721.14 CDS27846.2 - 0.77 10.6 4.5 0.21 12.3 0.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3932 PF13068.6 CDS27849.1 - 0.5 10.7 5.8 0.085 13.1 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) PRIMA1 PF16101.5 CDS27850.2 - 0.0059 16.6 10.1 0.013 15.6 10.1 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 VIR_N PF15912.5 CDS27850.2 - 0.0077 15.9 4.6 0.011 15.3 4.6 1.2 1 0 0 1 1 1 1 Virilizer, N-terminal Mito_fiss_reg PF05308.11 CDS27850.2 - 0.18 11.9 7.5 0.29 11.2 7.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CDS27850.2 - 0.2 11.1 9.8 0.26 10.7 9.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-C2H2 PF00096.26 CDS27851.2 - 0.0034 17.7 0.1 0.0034 17.7 0.1 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type ORC4_C PF14629.6 CDS27851.2 - 0.067 12.5 1.2 0.16 11.3 1.2 1.7 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus PRIMA1 PF16101.5 CDS27862.1 - 0.022 14.8 5.8 0.059 13.4 5.8 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C2H2_4 PF13894.6 CDS27863.2 - 5.4 8.1 7.9 2.1 9.4 4.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger SPRY PF00622.28 CDS27865.1 - 1e-17 64.3 0.4 6.6e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 SPRY domain PHD PF00628.29 CDS27865.1 - 0.0017 18.2 12.8 0.0017 18.2 12.8 1.9 2 0 0 2 2 2 1 PHD-finger zf-RING_11 PF17123.5 CDS27865.1 - 3.6 7.4 9.1 15 5.5 8.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C2H2 PF00096.26 CDS27867.1 - 1.5e-14 53.6 41.6 1.3e-05 25.4 0.8 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS27867.1 - 8.5e-13 48.1 35.3 1.7e-06 28.2 0.4 5.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS27867.1 - 2.2e-12 46.7 42.4 0.00034 21.2 0.5 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.7 CDS27867.1 - 8.2e-09 35.6 33.5 0.0075 16.6 1.7 5.7 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS27867.1 - 6.9e-07 29.4 35.2 0.052 13.8 1.7 5.6 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CDS27867.1 - 0.16 12.4 25.0 0.12 12.8 1.7 5.2 2 2 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 CDS27867.1 - 0.2 11.5 15.0 0.11 12.3 0.5 4.0 2 1 2 4 4 4 0 GAGA factor zf-U1 PF06220.12 CDS27867.1 - 0.95 9.3 6.8 1.8 8.4 0.5 2.6 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_3rep PF18868.1 CDS27867.1 - 2.8 8.6 15.0 11 6.7 0.5 4.5 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 CDS27867.1 - 3.7 7.5 9.7 10 6.1 0.9 3.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 CDS27867.1 - 5.5 7.0 25.4 3.7 7.5 0.3 4.6 4 0 0 4 4 4 0 SprT-like zinc ribbon domain TUDOR PF00567.24 CDS27868.1 - 6.6e-09 35.8 0.1 1.1e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 CDS27868.1 - 5.9e-07 29.0 1.8 7.4e-07 28.7 0.8 1.6 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) DUF4537 PF15057.6 CDS27868.1 - 0.0051 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 CDS27868.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_2 PF18104.1 CDS27868.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain LMBR1 PF04791.16 CDS27868.1 - 0.23 10.3 7.3 0.29 10.0 7.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein YTH PF04146.15 CDS27869.1 - 9.1e-39 133.1 0.0 9.1e-39 133.1 0.0 2.8 3 1 0 3 3 3 1 YT521-B-like domain Hap4_Hap_bind PF10297.9 CDS27869.1 - 0.067 13.3 0.5 0.16 12.2 0.5 1.6 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Glyco_hydro_106 PF17132.4 CDS27869.1 - 0.4 8.9 3.9 0.61 8.3 3.9 1.2 1 0 0 1 1 1 0 alpha-L-rhamnosidase RT_RNaseH_2 PF17919.1 CDS27870.1 - 4e-12 46.1 0.0 1.2e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS27870.1 - 1.5e-09 38.1 0.0 4.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS27870.1 - 0.079 12.5 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Porphobil_deam PF01379.20 CDS27871.1 - 1e-70 237.4 0.0 1.9e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CDS27871.1 - 2.7e-12 46.9 0.0 1.1e-11 45.0 0.0 2.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF3231 PF11553.8 CDS27871.1 - 0.0059 16.3 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) CSD PF00313.22 CDS27872.1 - 1.2e-19 69.9 0.0 2.2e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CDS27872.1 - 0.062 13.0 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain CzcE PF16986.5 CDS27872.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE DUF1509 PF07420.11 CDS27872.1 - 0.52 9.2 4.9 1 8.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF5575 PF17738.1 CDS27873.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5575) 7tm_1 PF00001.21 CDS27874.1 - 3.4e-08 33.1 6.3 3.4e-08 33.1 6.3 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) RhoGAP PF00620.27 CDS27875.1 - 2.7e-39 134.4 0.0 4.4e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CDS27875.1 - 3.2e-16 59.7 0.1 5.5e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDS27875.1 - 1.7e-09 38.1 0.3 4.2e-09 36.8 0.3 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CDS27875.1 - 0.018 15.3 0.1 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.25 CDS27876.1 - 1.7e-40 139.1 0.0 2e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27876.1 - 3.6e-16 59.2 0.0 4.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C23 PF05379.11 CDS27876.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Carlavirus endopeptidase 7TM-7TMR_HD PF07698.11 CDS27877.1 - 0.0064 16.3 5.6 0.0064 16.3 5.6 1.5 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase DUF3937 PF13073.6 CDS27877.1 - 0.0078 16.3 0.3 0.02 15.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3937) DUF4538 PF15061.6 CDS27877.1 - 2.1 8.1 4.6 0.66 9.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) NDUF_B12 PF08122.12 CDS27877.1 - 2.3 8.3 3.6 1.7 8.8 0.1 2.5 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Homeodomain PF00046.29 CDS27878.1 - 5.5e-22 77.4 9.3 1.1e-21 76.4 9.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS27878.1 - 0.064 13.2 0.5 0.21 11.6 0.5 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF2209 PF09974.9 CDS27878.1 - 0.12 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) RNase_P_p30 PF01876.16 CDS27880.1 - 5.4e-26 91.4 0.0 6.7e-25 87.8 0.0 2.1 1 1 0 1 1 1 1 RNase P subunit p30 Ldl_recept_b PF00058.17 CDS27881.1 - 3.3e-21 75.5 32.4 0.009 16.5 0.0 14.9 17 1 0 17 17 17 8 Low-density lipoprotein receptor repeat class B Ldl_recept_a PF00057.18 CDS27881.1 - 1.5e-12 47.5 32.5 1.1e-07 31.9 2.6 4.3 3 1 1 4 4 4 2 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.6 CDS27881.1 - 1.5e-07 31.6 55.9 4.9e-06 26.7 5.5 6.5 7 2 0 7 7 7 4 Coagulation Factor Xa inhibitory site SGL PF08450.12 CDS27881.1 - 2.1e-05 24.3 0.6 0.29 10.7 0.0 4.8 5 0 0 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region cEGF PF12662.7 CDS27881.1 - 0.91 9.5 24.3 0.025 14.5 1.2 4.6 4 0 0 4 4 4 0 Complement Clr-like EGF-like Glyco_transf_49 PF13896.6 CDS27883.1 - 3.3e-50 171.3 2.5 2.1e-39 135.8 0.7 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.20 CDS27883.1 - 9.3e-12 45.0 0.9 2.1e-11 43.9 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Regulator_TrmB PF11495.8 CDS27884.1 - 0.1 11.7 0.1 0.21 10.7 0.1 1.4 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB DUF1563 PF07599.11 CDS27884.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) DUF1041 PF06292.17 CDS27885.1 - 2.9e-24 85.5 0.3 8.8e-24 83.9 0.3 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) C2 PF00168.30 CDS27885.1 - 0.034 14.4 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 C2 domain I-set PF07679.16 CDS27887.1 - 3.7e-66 219.2 0.1 2.6e-17 62.7 0.0 9.0 9 0 0 9 9 9 6 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS27887.1 - 5.6e-55 183.9 1.2 1.3e-11 45.0 0.0 9.3 9 0 0 9 9 9 8 Immunoglobulin domain ig PF00047.25 CDS27887.1 - 7.7e-33 112.5 0.5 5.2e-07 29.8 0.0 8.5 8 0 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CDS27887.1 - 3.1e-30 104.3 0.8 7.5e-06 26.2 0.0 8.9 9 1 0 9 9 9 7 Immunoglobulin domain V-set PF07686.17 CDS27887.1 - 4.9e-15 55.6 0.5 0.059 13.6 0.0 8.3 7 3 0 7 7 7 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS27887.1 - 6.6e-07 29.3 0.2 0.17 11.9 0.0 4.8 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS27887.1 - 0.031 13.8 0.3 8.9 6.0 0.0 3.9 4 0 0 4 4 4 0 Immunoglobulin domain Lep_receptor_Ig PF06328.11 CDS27887.1 - 0.073 13.0 0.0 14 5.8 0.0 3.3 3 0 0 3 3 3 0 Ig-like C2-type domain MAD PF05557.13 CDS27887.1 - 0.24 9.7 7.8 0.16 10.3 2.1 2.3 2 0 0 2 2 2 0 Mitotic checkpoint protein Spectrin PF00435.21 CDS27887.1 - 0.94 10.0 4.5 5 7.7 0.0 3.5 4 0 0 4 4 4 0 Spectrin repeat YHS PF04945.13 CDS27889.2 - 6.5e-10 39.0 0.2 0.00076 19.5 0.1 2.8 2 0 0 2 2 2 2 YHS domain FAP206 PF12018.8 CDS27889.2 - 2.2e-05 24.1 0.2 0.0089 15.6 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function ADK PF00406.22 CDS27889.2 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase Dpy-30 PF05186.13 CDS27889.2 - 0.00083 19.0 0.3 0.0026 17.4 0.1 1.9 2 0 0 2 2 2 1 Dpy-30 motif zf-FLZ PF04570.14 CDS27889.2 - 0.055 12.9 4.3 0.16 11.5 4.3 1.8 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-FCS PF06467.14 CDS27889.2 - 0.17 11.8 0.4 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RVT_1 PF00078.27 CDS27890.1 - 6e-05 22.7 0.0 6.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5305 PF17231.2 CDS27892.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Lectin_N PF03954.14 CDS27892.1 - 0.09 12.5 0.8 0.32 10.7 1.1 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TMEM154 PF15102.6 CDS27892.1 - 0.1 12.5 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 TMEM154 protein family LRR19-TM PF15176.6 CDS27892.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4381 PF14316.6 CDS27892.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 CDS27892.1 - 0.49 11.3 2.4 0.59 11.0 0.3 2.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain BAMBI PF06211.12 CDS27892.1 - 0.8 10.0 4.2 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Ly49 PF08391.10 CDS27892.1 - 4.7 7.6 5.5 0.67 10.3 0.9 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region HAP1_N PF04849.13 CDS27893.1 - 2.4e-32 112.4 27.6 3.6e-32 111.8 27.6 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF3426 PF11906.8 CDS27893.1 - 0.14 12.4 0.7 1.8 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) GIT_CC PF16559.5 CDS27893.1 - 0.23 11.4 6.6 0.87 9.5 0.3 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SOGA PF11365.8 CDS27893.1 - 0.93 10.7 10.6 6.4 8.0 2.3 3.3 2 1 1 3 3 3 0 Protein SOGA DUF1664 PF07889.12 CDS27893.1 - 7.3 6.7 11.9 0.79 9.8 1.6 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) PRELI PF04707.14 CDS27894.1 - 2.1e-26 92.6 0.1 3.8e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 PRELI-like family FA_hydroxylase PF04116.13 CDS27895.1 - 4.8 7.5 8.1 1.9 8.9 1.0 3.2 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily NUC173 PF08161.12 CDS27896.2 - 9.4e-14 51.5 0.0 8.5e-13 48.4 0.0 2.7 2 1 0 2 2 2 1 NUC173 domain RT_RNaseH_2 PF17919.1 CDS27897.2 - 5e-30 103.5 0.4 2.1e-29 101.5 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS27897.2 - 6.1e-30 104.4 0.1 1.5e-29 103.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDS27897.2 - 8.9e-28 96.7 0.1 2.1e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS27897.2 - 4.8e-23 81.6 0.0 1.4e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS27897.2 - 2.6e-17 62.7 1.2 7e-17 61.3 1.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS27897.2 - 9.3e-05 22.6 0.1 0.00023 21.3 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDS27897.2 - 0.00018 21.2 0.0 0.00055 19.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDS27897.2 - 0.013 15.7 0.0 0.1 12.8 0.0 2.4 3 0 0 3 3 3 0 DDE domain Usp PF00582.26 CDS27898.1 - 1.3e-22 80.9 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Cation_efflux PF01545.21 CDS27899.2 - 8.5e-29 100.7 8.1 1.1e-28 100.4 8.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDS27899.2 - 1.1e-10 41.4 0.3 2.2e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4234 PF14018.6 CDS27899.2 - 0.063 13.4 1.5 0.67 10.1 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF587 PF04532.12 CDS27899.2 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF587) DUF2976 PF11190.8 CDS27899.2 - 4.1 7.3 5.8 1.6 8.6 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) OTU PF02338.19 CDS27900.1 - 4.2e-12 46.7 0.0 7.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDS27900.1 - 0.00015 21.3 0.0 0.059 12.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Phosphorylase PF00343.20 CDS27901.2 - 0 1128.1 0.0 0 1127.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF2634 PF10934.8 CDS27901.2 - 0.073 13.2 1.1 1.6 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2634) Med14 PF08638.11 CDS27903.1 - 3.5e-51 173.4 1.9 6.4e-51 172.5 1.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 eIF-5_eIF-2B PF01873.17 CDS27905.1 - 1.3e-34 118.6 0.0 1.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CDS27905.1 - 0.051 13.1 0.2 0.094 12.3 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Ribosomal_S27e PF01667.17 CDS27905.1 - 0.091 12.5 1.5 0.17 11.6 1.5 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 CDS27905.1 - 2.3 8.3 6.8 1.2 9.3 0.5 3.0 4 0 0 4 4 4 0 Zinc-ribbon ARID PF01388.21 CDS27906.1 - 1.8e-18 67.0 0.0 4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RBB1NT PF08169.11 CDS27906.1 - 1.2e-08 35.0 0.0 3.8e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 RBB1NT (NUC162) domain Tudor-knot PF11717.8 CDS27906.1 - 0.0018 18.1 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 CDS27906.1 - 0.035 14.5 0.4 17 5.9 0.0 3.9 3 0 0 3 3 3 0 PWWP domain BTB PF00651.31 CDS27907.1 - 2.2e-14 53.6 0.0 4.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 CDS27908.1 - 2.1e-38 130.8 2.1 2.2e-14 53.8 0.9 4.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27908.1 - 4.4e-29 100.5 2.2 2e-09 37.8 0.2 5.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS27908.1 - 2.8e-24 84.8 7.5 2.3e-05 24.6 0.5 6.7 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS27908.1 - 9.9e-21 71.6 6.3 0.0019 18.5 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 CDS27908.1 - 3.2e-18 65.3 12.8 0.02 15.3 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank_2 PF12796.7 CDS27911.1 - 6.5e-163 529.8 58.0 5e-18 65.5 0.7 12.7 2 2 13 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.30 CDS27911.1 - 1.4e-105 341.6 37.6 1.8e-06 28.1 0.0 23.4 23 0 0 23 23 23 20 Ankyrin repeat Ank_4 PF13637.6 CDS27911.1 - 2.5e-105 343.6 12.6 2.4e-10 40.7 0.0 15.3 9 5 7 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS27911.1 - 2e-101 319.5 25.9 1.7e-05 24.8 0.0 24.3 24 0 0 24 24 24 19 Ankyrin repeat Ank_5 PF13857.6 CDS27911.1 - 1.5e-79 261.0 34.0 8.6e-07 29.1 0.0 20.0 2 2 19 22 22 22 22 Ankyrin repeats (many copies) KH_1 PF00013.29 CDS27911.1 - 2.5e-10 40.0 2.2 5.6e-10 38.9 1.2 2.2 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CDS27911.1 - 0.0011 18.8 0.9 0.0051 16.7 0.2 2.5 2 0 0 2 2 2 1 KH domain FAA_hydro_N_2 PF18288.1 CDS27912.1 - 0.81 10.1 0.0 0.81 10.1 0.0 3.7 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 BEN PF10523.9 CDS27913.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 BEN domain DSPc PF00782.20 CDS27914.1 - 1.5e-22 79.8 0.0 2.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS27914.1 - 0.0032 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CDS27914.1 - 0.022 15.1 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CDS27914.1 - 0.038 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate RIG-I_C-RD PF11648.8 CDS27914.1 - 0.26 11.5 3.7 0.56 10.5 3.7 1.5 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf_UBZ PF18439.1 CDS27914.1 - 0.39 10.4 6.6 15 5.3 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Carboxyl_trans PF01039.22 CDS27915.1 - 2.7e-186 620.0 0.0 3.1e-186 619.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CDS27915.1 - 0.019 14.4 0.2 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) KH_1 PF00013.29 CDS27916.1 - 2.9e-07 30.2 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 KH domain Neur_chan_LBD PF02931.23 CDS27917.1 - 4.5e-95 317.2 8.0 2.7e-47 161.0 0.7 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS27917.1 - 1.4e-36 126.8 0.0 2.9e-19 70.1 0.1 2.9 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mic1 PF07035.12 CDS27918.1 - 4.3e-35 120.7 0.0 1.7e-34 118.8 0.0 1.8 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like Atg14 PF10186.9 CDS27919.1 - 3.4e-08 32.9 0.6 1.1e-07 31.3 0.6 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PIN_12 PF16289.5 CDS27919.1 - 0.017 15.6 0.2 0.028 14.9 0.2 1.3 1 0 0 1 1 1 0 PIN domain Methyltransf_25 PF13649.6 CDS27920.1 - 7.9e-15 55.3 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS27920.1 - 1.1e-14 54.6 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS27920.1 - 1.2e-12 48.4 0.0 2.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS27920.1 - 6.7e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS27920.1 - 4.8e-07 29.7 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CDS27920.1 - 0.0029 17.1 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain HobA PF12163.8 CDS27920.1 - 0.068 12.7 0.3 0.096 12.2 0.3 1.2 1 0 0 1 1 1 0 DNA replication regulator TPMT PF05724.11 CDS27920.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Elf1 PF05129.13 CDS27922.1 - 4.1e-30 103.7 2.4 4.5e-30 103.5 2.4 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 CDS27922.1 - 0.0056 17.0 2.7 0.01 16.2 2.7 1.5 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-LITAF-like PF10601.9 CDS27922.1 - 0.11 12.8 3.0 3.2 8.1 3.1 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Rubredoxin PF00301.20 CDS27922.1 - 0.14 12.2 0.5 0.14 12.2 0.5 2.1 2 0 0 2 2 2 0 Rubredoxin zf-Di19 PF05605.12 CDS27922.1 - 0.46 10.8 6.4 5.5 7.4 6.4 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cys_rich_CPXG PF14255.6 CDS27922.1 - 0.49 10.3 7.9 1.1 9.2 4.8 2.1 1 1 1 2 2 2 0 Cysteine-rich CPXCG zf-Sec23_Sec24 PF04810.15 CDS27922.1 - 2.7 8.1 8.8 0.83 9.8 1.7 2.8 2 1 2 4 4 4 0 Sec23/Sec24 zinc finger Pro_isomerase PF00160.21 CDS27923.1 - 7.2e-19 68.6 0.0 1.6e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDS27923.1 - 2.5e-15 56.0 0.1 5e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS27923.1 - 0.039 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAGI_u1 PF16663.5 CDS27923.1 - 0.15 12.2 3.1 0.27 11.4 0.4 2.6 3 0 0 3 3 3 0 Unstructured region on MAGI Ceramidase_alk PF04734.13 CDS27924.1 - 2.7e-46 158.3 0.2 3.2e-46 158.1 0.2 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal ODC_AZ PF02100.17 CDS27924.1 - 0.0042 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme UB2H PF14814.6 CDS27924.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain START PF01852.19 CDS27925.2 - 5e-09 35.9 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 START domain HTH_32 PF13565.6 CDS27926.1 - 0.0036 17.9 0.0 0.0046 17.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDS27926.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Ecm33 PF12454.8 CDS27926.1 - 0.25 11.5 0.5 0.75 10.0 0.1 1.9 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein PHD PF00628.29 CDS27927.1 - 9.3e-14 51.1 23.8 2e-08 34.0 8.8 2.6 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 CDS27927.1 - 3.8e-06 26.5 0.0 8.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 CDS27927.1 - 0.0025 17.3 0.7 0.0025 17.3 0.7 3.6 3 0 0 3 3 3 2 PHD-finger FHA PF00498.26 CDS27927.1 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 FHA domain C1_1 PF00130.22 CDS27927.1 - 5.7 6.9 20.6 0.9 9.5 5.5 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 CDS27928.1 - 0.011 15.2 3.3 0.028 13.9 3.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 CDS27928.1 - 2.9 7.9 5.3 8.5 6.4 4.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon FragX_IP PF05994.11 CDS27929.1 - 0 1188.1 1.5 0 1188.1 1.5 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 CDS27929.1 - 8.4e-10 38.4 1.8 2e-09 37.2 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Herpes_capsid PF06112.11 CDS27929.1 - 0.008 16.3 1.7 0.018 15.1 1.7 1.6 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein BP28CT PF08146.12 CDS27929.1 - 0.0085 16.0 1.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain AA_permease_2 PF13520.6 CDS27930.2 - 2.2e-59 201.4 46.2 2.6e-59 201.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS27930.2 - 6e-27 94.4 41.1 8.3e-27 93.9 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Mpv17_PMP22 PF04117.12 CDS27931.1 - 1e-20 73.7 5.9 2.1e-20 72.7 5.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family RRM_1 PF00076.22 CDS27932.1 - 2.4e-35 120.2 0.8 1.2e-13 50.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS27932.1 - 0.00094 19.2 0.4 1.7 8.8 0.1 3.8 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CDS27932.1 - 0.021 14.4 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS27932.1 - 0.12 12.3 0.0 3.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif TFIIE_beta PF02186.15 CDS27932.1 - 1 9.7 4.0 0.57 10.5 0.3 2.5 2 0 0 2 2 2 0 TFIIE beta subunit core domain CD225 PF04505.12 CDS27933.2 - 0.013 15.6 1.3 0.035 14.3 1.3 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF5576 PF17739.1 CDS27933.2 - 0.29 11.2 2.1 1.8 8.7 0.8 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5576) Itfg2 PF15907.5 CDS27934.1 - 1.4e-66 224.8 0.1 7.1e-64 216.0 0.0 2.9 2 1 0 2 2 2 2 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CDS27934.1 - 3.6e-05 24.3 1.0 0.24 12.0 0.1 3.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 CDS27934.1 - 0.0076 16.3 0.0 6.5 6.8 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 CDS27934.1 - 0.085 12.3 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Robl_LC7 PF03259.17 CDS27935.1 - 4e-10 39.3 0.0 5.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.10 CDS27935.1 - 0.00093 19.0 0.1 0.0012 18.7 0.1 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting CTP_transf_like PF01467.26 CDS27936.1 - 1.1e-29 103.5 0.0 1.7e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF4201 PF13870.6 CDS27937.1 - 1.7e-34 119.1 24.6 1.7e-34 119.1 24.6 3.3 3 1 0 3 3 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 CDS27937.1 - 0.0018 17.2 12.0 0.0018 17.2 12.0 4.6 1 1 2 4 4 4 1 Spc7 kinetochore protein ADIP PF11559.8 CDS27937.1 - 0.017 15.2 9.0 0.017 15.2 9.0 4.9 5 0 0 5 5 5 0 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.13 CDS27937.1 - 0.025 15.0 3.2 0.025 15.0 3.2 5.6 3 1 2 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Coat_F PF07875.12 CDS27937.1 - 0.028 14.6 1.2 0.12 12.6 1.2 2.1 1 0 0 1 1 1 0 Coat F domain Synaptobrevin PF00957.21 CDS27937.1 - 0.043 13.6 0.7 0.043 13.6 0.7 4.2 4 0 0 4 4 4 0 Synaptobrevin Jnk-SapK_ap_N PF09744.9 CDS27937.1 - 0.37 11.0 44.0 0.18 12.0 10.6 4.3 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 kleA_kleC PF17383.2 CDS27937.1 - 0.68 10.3 7.0 23 5.4 0.2 3.8 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A LPP PF04728.13 CDS27937.1 - 1 9.8 13.2 0.98 9.9 0.2 5.0 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DHR10 PF18595.1 CDS27937.1 - 3 7.9 43.5 0.49 10.5 6.1 5.4 4 1 1 6 6 6 0 Designed helical repeat protein 10 domain DUF2730 PF10805.8 CDS27937.1 - 5.5 7.1 13.0 2.6 8.2 0.8 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.12 CDS27937.1 - 8.1 6.5 42.3 0.27 11.3 5.7 5.3 5 0 0 5 5 5 0 TPR/MLP1/MLP2-like protein Dynamitin PF04912.14 CDS27938.1 - 1.1e-101 341.1 12.1 1.2e-101 340.9 12.1 1.0 1 0 0 1 1 1 1 Dynamitin IZUMO PF15005.6 CDS27938.1 - 0.05 14.1 4.2 0.21 12.1 0.0 2.7 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CENP-R PF06729.12 CDS27938.1 - 0.098 12.6 2.1 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 Kinetochore component, CENP-R YPEB PF14620.6 CDS27938.1 - 0.15 11.4 6.4 0.73 9.1 2.8 2.6 2 1 0 2 2 2 0 YpeB sporulation COG2 PF06148.11 CDS27938.1 - 0.27 11.3 5.0 0.52 10.4 0.7 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CDS27938.1 - 3.5 7.8 15.3 4.8 7.4 0.1 4.0 3 2 1 4 4 4 0 Golgi transport complex subunit 5 GreA_GreB_N PF03449.15 CDS27938.1 - 4.5 7.5 6.8 19 5.5 0.0 3.7 4 0 0 4 4 4 0 Transcription elongation factor, N-terminal CLZ PF16526.5 CDS27938.1 - 5.5 7.4 12.1 9.4 6.7 0.1 5.1 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Flavoprotein PF02441.19 CDS27939.1 - 1.9e-49 167.4 0.0 2.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein CNOT11 PF10155.9 CDS27940.1 - 3e-31 108.2 4.4 3e-31 108.2 4.4 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 RabGAP-TBC PF00566.18 CDS27941.2 - 1.3e-19 70.8 12.7 3.5e-10 39.9 0.3 4.2 4 0 0 4 4 4 3 Rab-GTPase-TBC domain PH_RBD PF12068.8 CDS27941.2 - 9.7e-18 64.2 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Rab-binding domain (RBD) TIP41 PF04176.13 CDS27944.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP41-like family Cpn60_TCP1 PF00118.24 CDS27945.1 - 2.8e-163 544.1 8.9 3.2e-163 543.9 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ank_5 PF13857.6 CDS27946.1 - 4.3e-39 132.1 1.5 1e-12 48.0 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS27946.1 - 7.5e-38 129.0 0.0 8.8e-15 55.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS27946.1 - 1.4e-36 124.4 5.7 1.7e-10 41.2 0.1 5.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS27946.1 - 4.7e-32 109.0 1.7 2.7e-06 27.6 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CDS27946.1 - 1.7e-31 104.7 0.4 0.00013 22.1 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Neil1-DNA_bind PF09292.10 CDS27946.1 - 0.088 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind Pkinase PF00069.25 CDS27947.1 - 1.6e-30 106.4 0.1 3e-27 95.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27947.1 - 8.6e-14 51.4 0.1 2.8e-13 49.7 0.1 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CDS27947.1 - 2.7e-06 26.9 0.1 4.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS27947.1 - 7.8e-05 22.4 0.6 0.00028 20.5 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 CDS27947.1 - 0.013 14.8 0.1 0.043 13.1 0.1 1.7 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CDS27947.1 - 0.016 14.8 0.5 0.033 13.8 0.5 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDS27947.1 - 0.19 11.6 0.6 0.85 9.5 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDS27948.1 - 1.5e-07 31.1 0.1 0.00043 19.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain DUF5109 PF17134.4 CDS27948.1 - 0.037 13.9 0.4 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5109) EAV_GS PF01309.18 CDS27948.1 - 0.043 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein 7tm_1 PF00001.21 CDS27949.1 - 5.7e-21 75.0 13.5 8.2e-21 74.5 13.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pkinase PF00069.25 CDS27950.1 - 1.9e-35 122.5 0.0 4.3e-31 108.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS27950.1 - 2.6e-22 79.3 0.0 2.5e-21 76.2 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 CDS27950.1 - 0.00035 20.3 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CDS27950.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDS27950.1 - 0.0064 15.9 0.5 0.014 14.7 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS27950.1 - 0.019 13.8 0.5 0.03 13.1 0.5 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDS27950.1 - 0.046 13.6 0.0 1.2 9.0 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS27950.1 - 0.062 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Histone PF00125.24 CDS27951.1 - 1.1e-49 168.1 3.1 1.3e-49 167.9 3.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDS27951.1 - 0.00027 21.3 0.1 0.00044 20.6 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDS27951.1 - 0.00037 20.6 0.3 0.00065 19.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDS27951.1 - 0.0029 18.2 0.8 0.0032 18.1 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CDS27951.1 - 0.0082 16.4 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS27951.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HECT PF00632.25 CDS27953.1 - 2.7e-30 105.9 0.0 3.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Histone PF00125.24 CDS27954.1 - 1.2e-52 177.8 2.7 1.5e-52 177.4 2.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS27954.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDS27954.1 - 0.00038 21.1 1.4 0.0005 20.7 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CDS27954.1 - 0.00061 20.1 0.1 0.00094 19.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CDS27954.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CDS27954.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DEAD PF00270.29 CDS27955.1 - 4.5e-31 108.0 0.0 4.8e-29 101.4 0.0 3.1 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS27955.1 - 7.1e-23 81.1 0.0 2e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CDS27955.1 - 8.2e-05 22.1 0.0 0.00046 19.6 0.0 2.1 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 CDS27955.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NCD2 PF04905.13 CDS27956.1 - 8.1e-22 77.5 0.0 1.8e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 NAB conserved region 2 (NCD2) WD40 PF00400.32 CDS27956.1 - 1.1e-07 32.3 0.2 0.3 12.0 0.0 4.6 3 0 0 3 3 3 2 WD domain, G-beta repeat LRR_8 PF13855.6 CDS27956.1 - 2.9e-05 23.7 0.6 8.1e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CDS27956.1 - 0.00029 21.2 1.8 0.0018 18.7 0.6 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) 14-3-3 PF00244.20 CDS27957.1 - 1.4e-35 122.9 1.3 1.6e-35 122.6 1.3 1.1 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M13 PF01431.21 CDS27960.1 - 0.0083 15.7 2.3 0.012 15.2 2.3 1.2 1 0 0 1 1 1 1 Peptidase family M13 CDT1_C PF16679.5 CDS27960.1 - 0.052 14.0 2.6 0.12 12.9 2.6 1.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Peptidase_C1 PF00112.23 CDS27962.1 - 1.9e-128 426.9 16.7 1e-65 221.9 5.2 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Propeptide_C1 PF08127.13 CDS27962.1 - 3.9e-18 65.0 0.0 3.3e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 CDS27962.1 - 0.075 11.8 13.6 2.7 6.7 1.1 4.0 4 0 0 4 4 4 0 Peptidase C1-like family DUF5082 PF16888.5 CDS27963.1 - 0.035 14.4 0.1 0.051 13.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4201 PF13870.6 CDS27963.1 - 0.039 13.7 0.3 0.059 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Lzipper-MIP1 PF14389.6 CDS27963.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TMF_DNA_bd PF12329.8 CDS27963.1 - 0.068 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Val_tRNA-synt_C PF10458.9 CDS27963.1 - 0.081 13.2 0.7 0.16 12.3 0.4 1.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PID PF00640.23 CDS27964.1 - 4.1e-29 101.4 0.0 1.4e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 CDS27964.1 - 6.7e-23 80.8 0.2 4e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDS27964.1 - 3.8e-13 49.1 0.1 4.3e-05 23.3 0.1 2.8 2 0 0 2 2 2 2 PDZ domain NRho PF16733.5 CDS27964.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain PH PF00169.29 CDS27965.2 - 5.8e-06 26.8 0.1 1.3e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 PH domain RA PF00788.23 CDS27965.2 - 2e-05 25.1 0.1 6.3e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Metallothio_Cad PF07846.11 CDS27965.2 - 0.27 11.4 8.0 4.8 7.4 1.0 2.5 2 0 0 2 2 2 0 Metallothionein family adh_short PF00106.25 CDS27966.1 - 3e-84 281.3 14.3 2.4e-42 144.6 2.3 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS27966.1 - 1e-76 257.6 4.7 3.1e-38 131.7 0.2 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS27966.1 - 2.6e-20 73.1 12.2 8.1e-11 42.2 3.1 3.7 2 2 0 2 2 2 2 KR domain Epimerase PF01370.21 CDS27966.1 - 1.4e-10 41.1 2.8 2.9e-06 26.9 0.3 3.0 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDS27966.1 - 2.1e-07 30.3 8.7 0.0035 16.4 1.2 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDS27966.1 - 0.0017 17.6 0.3 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein HATPase_c PF02518.26 CDS27966.1 - 0.0079 16.7 0.1 1.1 9.8 0.0 2.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TrkA_N PF02254.18 CDS27966.1 - 0.012 15.9 0.2 0.064 13.5 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain PrsW-protease PF13367.6 CDS27966.1 - 0.041 13.3 0.1 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease RmlD_sub_bind PF04321.17 CDS27966.1 - 0.13 11.4 0.3 12 4.9 0.1 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain RhoGEF PF00621.20 CDS27968.1 - 3.9e-21 76.1 0.0 6.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 CDS27968.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.3 1 0 0 1 1 1 0 PH domain PDZ_6 PF17820.1 CDS27969.1 - 9.6e-09 35.0 0.0 2.7e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDS27969.1 - 1.2e-06 28.8 0.1 5.7e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CDS27969.1 - 6.1e-05 23.3 0.1 0.00017 21.8 0.0 1.7 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 CDS27969.1 - 0.018 15.4 0.1 0.03 14.7 0.1 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain WD40 PF00400.32 CDS27970.1 - 1.1e-34 117.8 22.8 0.00015 22.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27970.1 - 4.6e-11 42.9 0.0 0.019 15.2 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDS27970.1 - 0.0022 17.4 0.0 0.044 13.1 0.0 2.6 1 1 2 3 3 3 1 WD40-like domain Myc-LZ PF02344.15 CDS27970.1 - 0.018 15.1 1.5 0.03 14.4 1.5 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain Cytochrom_D1 PF02239.16 CDS27970.1 - 0.17 10.4 0.0 0.45 9.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Syntaxin-6_N PF09177.11 CDS27971.1 - 0.0038 17.8 7.2 0.028 14.9 7.0 2.2 1 1 0 1 1 1 1 Syntaxin 6, N-terminal NopRA1 PF16201.5 CDS27971.1 - 0.0054 16.3 0.3 0.0063 16.1 0.3 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 V_ATPase_I PF01496.19 CDS27971.1 - 0.023 12.6 4.4 0.026 12.5 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.18 CDS27971.1 - 0.032 14.5 3.5 0.054 13.7 0.0 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA_3 PF07726.11 CDS27971.1 - 0.063 13.1 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FAD-SLDH PF12318.8 CDS27971.1 - 0.13 12.3 3.4 0.3 11.1 0.9 2.4 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase XPA_C PF05181.12 CDS27972.1 - 3.9e-23 81.2 0.0 9.9e-23 79.9 0.0 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CDS27972.1 - 2.6e-13 49.8 11.3 2.6e-13 49.8 11.3 1.7 2 0 0 2 2 2 1 XPA protein N-terminal FYVE PF01363.21 CDS27972.1 - 0.015 15.4 1.1 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 FYVE zinc finger CAP59_mtransfer PF11735.8 CDS27975.1 - 0.22 11.2 1.0 0.61 9.7 1.0 1.7 1 1 0 1 1 1 0 Cryptococcal mannosyltransferase 1 TSP_1 PF00090.19 CDS27977.1 - 2.3e-09 37.3 8.0 2.3e-09 37.3 8.0 2.8 2 0 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 CDS27977.1 - 6.4e-05 23.3 18.4 6.4e-05 23.3 18.4 3.7 3 1 0 3 3 3 1 Somatomedin B domain ubiquitin PF00240.23 CDS27978.2 - 2.3e-16 59.3 0.1 4.5e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS27978.2 - 0.0001 22.0 0.5 0.00018 21.2 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ALIX_LYPXL_bnd PF13949.6 CDS27978.2 - 0.01 15.2 0.5 0.023 14.0 0.5 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV BAG6 PF12057.8 CDS27978.2 - 0.012 15.3 11.8 0.45 10.2 0.1 5.3 4 1 1 5 5 5 0 BCL2-associated athanogene 6 Rad60-SLD_2 PF13881.6 CDS27978.2 - 0.048 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDS27978.2 - 0.075 13.6 0.0 0.26 11.9 0.0 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Nop53 PF07767.11 CDS27980.1 - 7.6e-13 48.6 34.8 3.9e-07 29.8 8.7 2.2 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) Nucleic_acid_bd PF13820.6 CDS27980.1 - 0.061 13.2 4.1 0.24 11.3 2.6 2.5 2 1 0 2 2 2 0 Putative nucleic acid-binding region DNApol_Exo PF18136.1 CDS27980.1 - 1.4 8.0 8.9 2.7 7.1 8.9 1.4 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain cNMP_binding PF00027.29 CDS27981.2 - 1.7e-35 120.9 0.0 7.5e-13 48.4 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CDS27981.2 - 2.5e-20 73.5 0.1 8.7e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase CHDCT2 PF08074.11 CDS27982.2 - 1.1e-67 227.4 0.3 3e-67 226.1 0.3 1.8 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.23 CDS27982.2 - 6.8e-58 196.1 0.0 1.5e-57 194.9 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1086 PF06461.11 CDS27982.2 - 8.7e-38 129.3 0.0 2.6e-37 127.7 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 CDS27982.2 - 2e-22 79.0 2.6 5.8e-22 77.5 2.6 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.29 CDS27982.2 - 1.4e-20 72.9 25.0 4.5e-11 42.5 6.3 2.5 2 0 0 2 2 2 2 PHD-finger CHDNT PF08073.12 CDS27982.2 - 5.5e-18 64.7 0.9 1.3e-17 63.5 0.4 2.0 2 0 0 2 2 1 1 CHDNT (NUC034) domain Chromo PF00385.24 CDS27982.2 - 2.4e-14 53.0 2.2 2e-11 43.6 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CDS27982.2 - 1.9e-09 37.7 0.0 4.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS27982.2 - 3.3e-08 33.9 0.1 4e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 CDS27982.2 - 4.6e-06 26.8 5.7 0.037 14.3 1.4 2.7 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CDS27982.2 - 0.0013 18.3 8.4 0.095 12.3 1.9 2.6 2 0 0 2 2 2 2 PHD-finger HDA2-3 PF11496.8 CDS27982.2 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 CDS27982.2 - 0.025 14.9 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 1 0 AAA domain zf-PHD-like PF15446.6 CDS27982.2 - 0.12 12.0 8.5 2.1 8.0 2.0 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 CDS27982.2 - 0.21 11.5 12.3 2.1 8.3 1.2 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UCH_C PF18031.1 CDS27982.2 - 2.6 8.0 5.2 10 6.1 5.2 2.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases GPP34 PF05719.11 CDS27983.1 - 6.6e-53 179.8 0.0 8.3e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) NEMP PF10225.9 CDS27984.1 - 3.7e-13 49.7 15.7 6.4e-13 49.0 15.7 1.4 1 1 0 1 1 1 1 NEMP family TLE_N PF03920.15 CDS27985.1 - 1.2e-58 196.9 4.9 1.8e-58 196.3 4.9 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 CDS27985.1 - 5.4e-09 36.5 14.9 0.38 11.7 0.2 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS27985.1 - 0.00031 21.0 0.1 0.0021 18.3 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS27985.1 - 0.14 12.0 0.0 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S18 PF01084.20 CDS27985.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 Cytochrom_D1 PF02239.16 CDS27985.1 - 0.23 10.0 0.0 0.52 8.8 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain SKA2 PF16740.5 CDS27985.1 - 2.6 7.8 6.0 0.7 9.7 1.9 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 zf-met PF12874.7 CDS27986.1 - 0.0012 19.2 0.5 2.9 8.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type KCT2 PF17818.1 CDS27986.1 - 0.72 10.0 5.2 2 8.5 5.2 1.7 1 0 0 1 1 1 0 Keratinocyte-associated gene product AKAP95 PF04988.12 CDS27986.1 - 1.8 8.8 4.4 11 6.2 0.0 2.9 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) PSI PF01437.25 CDS27987.1 - 0.0037 17.8 13.3 0.0053 17.3 13.3 1.2 1 0 0 1 1 1 1 Plexin repeat Nas2_N PF18265.1 CDS27988.1 - 3.1e-28 97.5 0.1 4.7e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CDS27988.1 - 3.9e-07 29.8 0.1 6.9e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS27988.1 - 0.00021 21.5 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDS27988.1 - 0.002 18.5 0.0 0.0058 16.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Laminin_II PF06009.12 CDS27988.1 - 0.33 11.0 1.5 0.46 10.5 0.2 1.8 2 0 0 2 2 2 0 Laminin Domain II DUF3656 PF12392.8 CDS27989.2 - 0.081 13.6 0.2 0.14 12.8 0.2 1.4 1 0 0 1 1 1 0 Collagenase GTP_EFTU PF00009.27 CDS27990.1 - 2e-73 246.1 0.0 2e-52 177.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDS27990.1 - 2.8e-63 211.2 0.0 7e-39 132.6 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDS27990.1 - 1.3e-17 63.9 5.0 2.3e-14 53.5 0.3 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDS27990.1 - 1.2e-05 25.3 0.5 0.0033 17.5 0.0 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS27990.1 - 0.0036 17.2 0.2 0.7 9.8 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU_D4 PF14578.6 CDS27990.1 - 0.012 15.5 9.2 0.026 14.4 0.8 3.1 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Fibrinogen_aC PF12160.8 CDS27990.1 - 0.018 14.9 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha C domain FlpD PF02662.16 CDS27990.1 - 0.083 12.9 0.0 0.6 10.1 0.0 2.3 3 0 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit Dynamin_N PF00350.23 CDS27990.1 - 0.14 12.2 0.3 66 3.5 0.0 3.7 4 0 0 4 4 4 0 Dynamin family Dynein_light PF01221.18 CDS27992.1 - 1.5e-29 102.1 0.2 1.8e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm6 PF14434.6 CDS27992.1 - 0.015 15.3 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Immunity protein Imm6 SapB_1 PF05184.15 CDS27992.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Saposin-like type B, region 1 Dynein_light PF01221.18 CDS27993.1 - 3.9e-10 39.9 2.6 2.2e-08 34.3 0.1 2.2 2 0 0 2 2 2 2 Dynein light chain type 1 HSP70 PF00012.20 CDS27994.1 - 2e-78 264.1 6.2 6.4e-78 262.4 6.2 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDS27994.1 - 0.00076 18.4 2.5 0.41 9.4 0.1 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 CDS27994.1 - 0.0066 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain T2SSF PF00482.23 CDS27994.1 - 0.04 13.9 1.3 0.6 10.1 0.2 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Coatomer_E PF04733.14 CDS27995.1 - 7.8e-64 215.9 1.0 9.6e-64 215.6 1.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CDS27995.1 - 8.7e-08 32.6 6.2 6.1e-05 23.5 2.3 4.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDS27995.1 - 3.2e-05 24.1 1.1 0.00027 21.1 0.8 2.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS27995.1 - 4.1e-05 23.4 2.0 0.0018 18.2 0.1 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS27995.1 - 6.2e-05 23.5 0.3 0.059 14.2 0.2 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS27995.1 - 0.0006 20.4 0.1 0.0043 17.7 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS27995.1 - 0.0089 15.8 3.6 0.023 14.5 0.0 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 CDS27995.1 - 0.012 14.5 0.1 0.04 12.8 0.1 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 CDS27995.1 - 0.016 15.4 0.1 0.23 11.7 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat FliD_C PF07195.12 CDS27995.1 - 0.028 13.8 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPR_10 PF13374.6 CDS27995.1 - 0.16 11.9 1.3 1.7 8.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.16 CDS27996.1 - 9.1e-09 35.1 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Casc1_N PF15927.5 CDS27997.1 - 9.7e-18 64.6 0.2 2.9e-17 63.0 0.2 1.9 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus Casc1 PF12366.8 CDS27997.1 - 0.00038 20.1 1.9 0.19 11.2 0.1 3.5 3 0 0 3 3 3 2 Cancer susceptibility candidate 1 Cullin PF00888.22 CDS27998.1 - 5.2e-129 431.6 2.2 6.8e-129 431.3 2.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS27998.1 - 2.2e-24 85.3 0.2 6.5e-24 83.7 0.2 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Linker_histone PF00538.19 CDS27998.1 - 0.16 12.4 0.1 9.3 6.7 0.0 2.9 3 0 0 3 3 3 0 linker histone H1 and H5 family Furin-like PF00757.20 CDS27999.2 - 1.2e-22 80.4 30.5 2.7e-22 79.2 30.5 1.5 1 0 0 1 1 1 1 Furin-like cysteine rich region Recep_L_domain PF01030.24 CDS27999.2 - 2.9e-22 78.9 0.0 6.1e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain fn3 PF00041.21 CDS27999.2 - 1.3e-11 44.6 0.1 1.1e-05 25.7 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain GF_recep_IV PF14843.6 CDS27999.2 - 1.1 9.1 36.5 0.45 10.3 25.5 2.9 2 0 0 2 2 2 0 Growth factor receptor domain IV RTC PF01137.21 CDS28000.1 - 3.1e-48 163.9 0.0 3.7e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDS28000.1 - 2.9e-25 88.8 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4201 PF13870.6 CDS28001.1 - 1.1e-27 97.0 27.5 1.1e-27 97.0 27.5 1.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4201) NIR_SIR_ferr PF03460.17 CDS28001.1 - 0.0019 18.0 0.1 0.3 11.0 0.0 3.1 3 1 1 4 4 4 1 Nitrite/Sulfite reductase ferredoxin-like half domain EF-hand_3 PF09069.11 CDS28001.1 - 0.0047 17.3 1.1 0.009 16.4 0.2 1.9 2 0 0 2 2 2 1 EF-hand AAA_13 PF13166.6 CDS28001.1 - 0.011 14.4 20.5 0.013 14.2 20.5 1.1 1 0 0 1 1 1 0 AAA domain Intein_splicing PF14890.6 CDS28001.1 - 2.6 8.0 8.4 2.4 8.1 5.5 2.1 1 1 1 2 2 2 0 Intein splicing domain Histone_HNS PF00816.21 CDS28001.1 - 2.6 8.9 7.4 0.35 11.7 0.5 2.8 1 1 2 3 3 3 0 H-NS histone family Vps51 PF08700.11 CDS28002.1 - 3.2e-08 33.5 0.0 9.8e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Fibin PF15819.5 CDS28004.1 - 0.13 12.0 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Fin bud initiation factor homologue AXH PF08517.12 CDS28007.1 - 8.8e-21 74.6 1.8 4.3e-16 59.5 1.0 2.2 1 1 1 2 2 2 2 Ataxin-1 and HBP1 module (AXH) CAP PF00188.26 CDS28008.1 - 2.5e-13 51.0 1.6 3.7e-13 50.4 1.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2877 PF11392.8 CDS28008.1 - 0.13 13.0 0.3 0.55 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Meleagrin PF08189.11 CDS28008.1 - 1.1 9.0 7.5 0.16 11.7 1.7 2.5 1 1 1 2 2 2 0 Meleagrin/Cygnin family Viral_Beta_CD PF04530.12 CDS28008.1 - 7.6 6.8 9.2 17 5.7 0.1 3.2 3 0 0 3 3 3 0 Viral Beta C/D like family CAP PF00188.26 CDS28009.1 - 3.2e-14 53.8 0.9 4.3e-14 53.4 0.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PLA2_inh PF02988.15 CDS28009.1 - 0.0093 16.6 0.4 0.0093 16.6 0.4 2.5 2 1 0 2 2 2 1 Phospholipase A2 inhibitor AXH PF08517.12 CDS28010.2 - 0.027 15.0 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Chordopox_A15 PF05846.12 CDS28012.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A15 protein CAP PF00188.26 CDS28015.2 - 1.1e-12 48.9 2.4 1.7e-12 48.3 2.4 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDS28017.2 - 7e-15 56.0 2.1 1e-14 55.5 2.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NusG_II PF07009.11 CDS28017.2 - 1.1 9.5 5.3 1.1 9.5 0.5 2.3 2 0 0 2 2 2 0 NusG domain II TB2_DP1_HVA22 PF03134.19 CDS28018.1 - 0.091 12.7 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DUF4184 PF13803.6 CDS28018.1 - 2.1 8.0 9.2 4.6 6.9 9.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) DUF3413 PF11893.8 CDS28018.1 - 2.2 7.4 15.5 0.84 8.8 13.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) MBOAT PF03062.19 CDS28019.2 - 2.7e-52 178.2 26.6 1.3e-28 100.4 0.9 4.4 4 0 0 4 4 4 4 MBOAT, membrane-bound O-acyltransferase family Metallothio_11 PF02066.15 CDS28019.2 - 0.06 13.5 1.3 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Metallothionein family 11 DUF3506 PF12014.8 CDS28019.2 - 0.14 12.2 0.1 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) zf-H2C2_2 PF13465.6 CDS28020.1 - 0.037 14.5 0.3 0.037 14.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 CDS28020.1 - 0.28 11.7 3.2 0.78 10.3 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28020.1 - 1.7 9.7 4.9 13 6.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_35 PF01301.19 CDS28021.1 - 8.1e-87 291.8 0.0 1.2e-86 291.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CDS28021.1 - 0.0004 19.8 0.0 0.034 13.5 0.0 2.3 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CDS28021.1 - 0.0058 17.2 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain RNA_pol_Rpc4 PF05132.14 CDS28022.1 - 0.00038 20.9 1.4 0.00047 20.6 0.0 1.8 2 1 0 2 2 2 1 RNA polymerase III RPC4 UBA2_C PF16195.5 CDS28022.1 - 0.066 13.9 3.9 26 5.6 0.0 3.3 2 1 1 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus DHHC PF01529.20 CDS28023.1 - 2.5e-31 108.6 11.9 2.5e-31 108.6 11.9 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 CDS28023.1 - 0.25 11.4 4.4 0.51 10.4 4.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon IGFBP PF00219.18 CDS28023.1 - 0.29 11.8 4.7 0.56 10.9 4.7 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Helicase_C PF00271.31 CDS28024.1 - 5.1e-21 75.1 0.2 1.4e-20 73.7 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS28024.1 - 2.5e-15 56.7 0.0 4.6e-14 52.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS28024.1 - 1.8e-14 54.1 0.0 3.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 CDS28024.1 - 6.3e-08 33.2 7.5 0.047 14.6 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDS28024.1 - 0.0013 17.8 0.0 2.5 7.0 0.0 3.4 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 CDS28024.1 - 0.0095 16.2 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Glyco_transf_41 PF13844.6 CDS28025.1 - 5.2e-250 829.7 0.0 6.8e-250 829.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.28 CDS28025.1 - 1.6e-87 284.1 35.9 2e-08 33.7 0.1 13.7 14 0 0 14 14 14 11 Tetratricopeptide repeat TPR_11 PF13414.6 CDS28025.1 - 5.4e-84 275.6 39.0 4e-11 42.4 1.2 12.7 3 2 10 13 13 12 12 TPR repeat TPR_2 PF07719.17 CDS28025.1 - 6.6e-73 235.1 34.3 2e-06 27.4 0.1 13.6 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28025.1 - 3.2e-64 208.8 42.3 8.7e-08 32.0 0.2 13.9 15 0 0 15 15 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 CDS28025.1 - 1.6e-63 205.7 23.5 4.5e-05 23.3 0.0 13.4 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28025.1 - 3.9e-46 155.2 48.1 1.5e-11 44.4 1.6 9.0 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 CDS28025.1 - 1.4e-42 140.7 20.2 0.00075 20.1 0.0 13.0 4 3 9 13 13 13 9 Tetratricopeptide repeat TPR_16 PF13432.6 CDS28025.1 - 2.7e-40 136.7 21.3 4.7e-08 33.6 0.1 7.7 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28025.1 - 1.2e-38 128.3 16.1 0.00012 21.8 0.1 12.9 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28025.1 - 1.4e-34 118.4 27.4 1.9e-05 25.1 0.8 9.3 2 2 7 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.6 CDS28025.1 - 1.6e-34 116.8 50.8 5.6e-06 26.0 1.1 12.5 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28025.1 - 1.1e-15 57.6 12.9 0.0029 17.7 0.6 6.0 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDS28025.1 - 1.8e-15 56.5 16.9 0.53 11.0 0.1 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat NARP1 PF12569.8 CDS28025.1 - 6.2e-12 45.2 7.3 0.0027 16.7 0.1 5.3 1 1 3 5 5 5 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 CDS28025.1 - 8.5e-10 38.5 11.4 4e-05 23.1 1.1 5.7 1 1 3 5 5 5 2 MalT-like TPR region TPR_4 PF07721.14 CDS28025.1 - 1e-08 35.0 17.5 0.031 14.9 0.2 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDS28025.1 - 1e-07 31.5 11.7 0.00035 19.9 4.5 4.6 2 2 1 3 3 3 2 Tetratricopeptide repeat FAT PF02259.23 CDS28025.1 - 9.9e-07 28.3 0.1 1.2 8.3 0.0 5.6 2 2 1 4 4 4 1 FAT domain EST1_DNA_bind PF10373.9 CDS28025.1 - 3.2e-05 23.6 18.5 0.13 11.8 0.3 5.6 5 1 1 6 6 6 3 Est1 DNA/RNA binding domain Wzy_C_2 PF11846.8 CDS28025.1 - 6.2e-05 23.0 7.7 0.056 13.4 0.4 4.2 3 1 1 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 CDS28025.1 - 0.00013 22.4 15.6 0.55 10.6 1.2 5.2 2 2 3 5 5 5 2 Bacterial transcriptional activator domain T2SSF PF00482.23 CDS28025.1 - 0.00031 20.7 0.2 0.014 15.3 0.1 3.1 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F TPR_21 PF09976.9 CDS28025.1 - 0.0011 18.8 11.3 8.9 6.0 0.3 5.6 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 CDS28025.1 - 0.0037 16.7 16.9 0.15 11.4 1.3 4.9 3 1 2 5 5 5 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 CDS28025.1 - 0.0075 16.3 25.5 8 6.6 0.0 8.9 9 1 1 10 10 9 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CDS28025.1 - 0.015 15.6 14.3 3.2 8.2 0.1 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 CDS28025.1 - 0.12 12.1 0.9 58 3.4 0.0 4.3 3 2 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 CDS28025.1 - 0.13 11.7 5.3 0.94 9.0 0.0 4.8 5 2 2 7 7 6 0 SHNi-TPR RPN7 PF10602.9 CDS28025.1 - 0.14 11.9 8.3 3.4 7.4 0.1 5.3 3 2 3 6 6 5 0 26S proteasome subunit RPN7 Coatomer_E PF04733.14 CDS28025.1 - 0.14 11.6 2.5 9.2 5.6 0.1 3.5 3 1 1 4 4 4 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 CDS28025.1 - 0.14 12.3 1.7 3.1 8.0 0.1 3.5 3 1 1 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 CDS28025.1 - 0.16 12.0 12.9 13 5.9 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDS28025.1 - 1.1 9.2 9.9 41 4.2 0.0 5.6 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 CDS28025.1 - 2.4 8.4 21.8 0.075 13.3 0.7 5.6 3 2 4 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 IFRD PF05004.13 CDS28027.1 - 2.4e-43 148.4 0.0 3.8e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 CDS28027.1 - 1.3e-13 51.2 2.0 1.3e-13 51.2 2.0 2.1 2 0 0 2 2 2 1 Interferon-related protein conserved region DUF3535 PF12054.8 CDS28027.1 - 0.0074 15.6 1.1 0.014 14.6 0.3 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) NB-LRR PF12061.8 CDS28027.1 - 0.03 13.7 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 Late blight resistance protein R1 HEAT PF02985.22 CDS28027.1 - 0.17 12.2 0.8 9.5 6.8 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat SIR2 PF02146.17 CDS28029.1 - 2.8e-22 79.5 1.1 8.6e-19 68.1 0.4 3.3 2 1 0 2 2 2 1 Sir2 family Nup_retrotrp_bd PF10599.9 CDS28029.1 - 0.0015 19.1 0.5 0.0026 18.4 0.5 1.4 1 0 0 1 1 1 1 Retro-transposon transporting motif Jnk-SapK_ap_N PF09744.9 CDS28031.1 - 6.7e-32 110.9 7.1 6.7e-32 110.9 7.1 1.9 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 RILP PF11461.8 CDS28031.1 - 0.006 16.8 0.2 0.026 14.7 0.2 2.1 1 0 0 1 1 1 1 Rab interacting lysosomal protein Syntaxin_2 PF14523.6 CDS28031.1 - 0.0063 16.9 3.5 0.025 14.9 3.5 2.1 1 0 0 1 1 1 1 Syntaxin-like protein Phage_Mu_Gam PF07352.12 CDS28031.1 - 0.036 14.0 4.7 0.069 13.1 4.7 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BAR PF03114.18 CDS28031.1 - 0.055 13.1 5.3 0.13 11.9 5.3 1.6 1 0 0 1 1 1 0 BAR domain GED PF02212.18 CDS28031.1 - 0.16 12.1 2.4 3.9 7.7 0.2 2.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF4315 PF14193.6 CDS28031.1 - 0.2 11.7 7.5 0.7 9.9 7.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) ABC_tran_Xtn PF12848.7 CDS28031.1 - 0.77 9.8 11.3 0.078 13.0 4.9 2.4 1 1 1 2 2 2 0 ABC transporter Mod_r PF07200.13 CDS28031.1 - 1.5 8.9 13.9 0.48 10.5 9.7 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CorA PF01544.18 CDS28031.1 - 7.8 5.7 7.9 1.5 8.0 3.9 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein LRR_8 PF13855.6 CDS28032.1 - 1.8e-10 40.4 11.5 2.3e-09 36.9 1.7 3.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_5 PF13306.6 CDS28032.1 - 1.8e-05 24.7 0.1 5.2e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDS28032.1 - 0.0025 18.2 9.0 0.95 10.0 0.2 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRRCT PF01463.24 CDS28032.1 - 0.01 16.3 0.1 0.052 14.1 0.1 2.3 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRR_1 PF00560.33 CDS28032.1 - 1.4 9.7 0.0 1.4 9.7 0.0 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat Ras PF00071.22 CDS28033.1 - 4.2e-43 146.8 0.0 4.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS28033.1 - 3.6e-24 85.3 0.0 5.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS28033.1 - 5e-08 32.6 0.0 7.6e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS28033.1 - 0.0017 17.8 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS28033.1 - 0.0018 18.4 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDS28033.1 - 0.035 13.6 0.0 0.046 13.2 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.9 CDS28033.1 - 0.06 12.5 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.9 CDS28033.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PDZ PF00595.24 CDS28034.1 - 2.5e-14 53.4 0.0 4.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS28034.1 - 4.5e-06 26.4 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS28034.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain SPATA48 PF15073.6 CDS28034.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 PALP PF00291.25 CDS28035.2 - 3.6e-45 154.6 0.2 5.5e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RRM_1 PF00076.22 CDS28035.2 - 6e-18 64.4 0.0 7.7e-17 60.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p25-alpha PF05517.12 CDS28037.1 - 5.1e-45 153.4 8.0 5.9e-45 153.2 8.0 1.0 1 0 0 1 1 1 1 p25-alpha HU-CCDC81_bac_2 PF18175.1 CDS28037.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Chitin_synth_1 PF01644.17 CDS28038.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase MMS22L_C PF14911.6 CDS28040.2 - 9.2e-08 31.6 0.3 3.4e-07 29.7 0.2 2.0 1 1 1 2 2 2 1 S-phase genomic integrity recombination mediator, C-terminal Reticulon PF02453.17 CDS28041.1 - 2.2e-24 86.2 5.5 4.2e-24 85.3 5.5 1.5 1 0 0 1 1 1 1 Reticulon Kelch_1 PF01344.25 CDS28041.1 - 1.3e-08 34.3 0.3 0.012 15.2 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDS28041.1 - 2.5e-05 24.4 0.0 1 9.8 0.0 3.8 3 0 0 3 3 3 2 Kelch motif BACK PF07707.15 CDS28041.1 - 0.00065 19.8 0.4 0.0016 18.5 0.4 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Glyoxal_oxid_N PF07250.11 CDS28041.1 - 0.0027 17.0 0.0 0.0089 15.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus Kelch_5 PF13854.6 CDS28041.1 - 0.0044 17.0 0.1 3.2 7.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CDS28041.1 - 0.012 15.6 0.0 0.012 15.6 0.0 3.3 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF5349 PF17298.2 CDS28041.1 - 0.15 11.8 2.0 0.24 11.1 2.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DNA_repr_REX1B PF14966.6 CDS28041.1 - 0.17 12.6 1.3 2.3 8.9 0.1 2.5 2 0 0 2 2 2 0 DNA repair REX1-B GDPD PF03009.17 CDS28042.1 - 8.1e-30 104.4 0.1 1.3e-24 87.3 0.1 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CDS28042.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain GDPD_2 PF13653.6 CDS28042.1 - 0.16 12.5 0.0 0.61 10.6 0.0 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PAXX PF15384.6 CDS28043.1 - 0.058 13.1 0.2 0.13 12.0 0.1 1.6 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Pkinase PF00069.25 CDS28044.1 - 2.4e-53 181.2 0.0 7.7e-53 179.5 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.29 CDS28044.1 - 9.4e-50 168.8 0.1 2.1e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.17 CDS28044.1 - 1.6e-34 119.4 0.0 6.1e-34 117.5 0.0 2.0 1 0 0 1 1 1 1 Protein tyrosine kinase PI3_PI4_kinase PF00454.27 CDS28044.1 - 1e-31 110.7 0.0 1e-31 110.7 0.0 3.8 3 1 0 3 3 2 1 Phosphatidylinositol 3- and 4-kinase Helicase_C PF00271.31 CDS28044.1 - 8e-29 100.2 0.4 5.5e-27 94.3 0.0 3.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain PI3Ka PF00613.20 CDS28044.1 - 1.6e-15 57.0 0.9 3.8e-15 55.8 0.9 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDS28044.1 - 4.1e-14 52.7 0.3 3.5e-12 46.4 0.0 3.4 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 CDS28044.1 - 2.3e-06 27.7 0.0 6.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain Kinase-like PF14531.6 CDS28044.1 - 0.00087 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 CDS28044.1 - 0.0053 17.0 0.2 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain NEMP PF10225.9 CDS28044.1 - 0.37 10.4 2.6 1.9 8.1 2.6 2.2 1 0 0 1 1 1 0 NEMP family 5_nucleotid PF05761.14 CDS28045.1 - 5.6e-141 470.6 0.0 7.3e-141 470.2 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase family FAR1 PF03101.15 CDS28045.1 - 8.1e-06 26.5 0.4 0.00024 21.7 0.0 2.8 3 0 0 3 3 3 1 FAR1 DNA-binding domain HAD_2 PF13419.6 CDS28045.1 - 0.1 12.7 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FLYWCH PF04500.16 CDS28045.1 - 0.11 12.6 0.3 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain W2 PF02020.18 CDS28046.1 - 2e-18 66.3 2.9 5.2e-18 65.0 2.9 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CDS28046.1 - 2.9e-10 39.5 5.7 0.0011 18.6 0.3 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CDS28046.1 - 0.0006 18.1 0.3 0.00096 17.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CDS28046.1 - 0.001 18.8 6.0 0.014 15.1 0.4 3.5 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase TFIIS_C PF01096.18 CDS28047.1 - 6.7e-18 64.3 3.5 6.7e-18 64.3 3.5 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 CDS28047.1 - 0.00053 19.9 1.4 0.00053 19.9 1.4 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 CDS28047.1 - 0.005 16.5 1.6 0.016 14.9 1.6 1.9 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.6 CDS28047.1 - 0.01 15.7 1.9 2 8.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 CDS28047.1 - 0.42 10.7 6.4 0.58 10.3 0.7 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Dof PF02701.15 CDS28047.1 - 3.1 8.0 10.8 0.1 12.8 2.0 2.4 2 1 0 2 2 2 0 Dof domain, zinc finger RNA_POL_M_15KD PF02150.16 CDS28047.1 - 7.9 6.5 12.4 2.8 7.9 1.9 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DNA_ligase_ZBD PF03119.16 CDS28047.1 - 8 6.6 11.2 4.6 7.4 4.4 3.2 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Rubredoxin PF00301.20 CDS28047.1 - 8.4 6.5 10.2 20 5.3 0.6 3.3 3 0 0 3 3 3 0 Rubredoxin Macro PF01661.21 CDS28048.1 - 7.7e-38 129.2 0.3 1.3e-37 128.4 0.3 1.4 1 0 0 1 1 1 1 Macro domain Homeobox_KN PF05920.11 CDS28049.2 - 2.1e-20 72.3 0.7 2.1e-20 72.3 0.7 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CDS28049.2 - 2.4e-08 33.7 0.4 4.4e-08 32.8 0.4 1.4 1 0 0 1 1 1 1 Homeodomain CAP PF00188.26 CDS28050.1 - 3.2e-15 57.1 0.5 4.9e-15 56.5 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family C1_1 PF00130.22 CDS28051.2 - 7.2e-10 38.6 2.7 1.4e-09 37.7 2.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RGS-like PF09128.11 CDS28051.2 - 1.5e-09 37.9 0.4 4.2e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain RGS PF00615.19 CDS28051.2 - 4.1e-06 27.1 0.0 1.4e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain C1_2 PF03107.16 CDS28051.2 - 0.028 14.7 1.0 0.065 13.6 1.0 1.6 1 0 0 1 1 1 0 C1 domain RFX5_N PF18326.1 CDS28051.2 - 0.055 13.2 0.4 0.19 11.5 0.4 2.0 1 0 0 1 1 1 0 RFX5 N-terminal domain Nup160 PF11715.8 CDS28052.2 - 1e-23 83.8 2.5 8.7e-23 80.8 2.5 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Cadherin PF00028.17 CDS28055.1 - 1.7e-62 207.9 2.6 6.3e-07 29.7 0.0 11.0 9 2 1 10 10 10 10 Cadherin domain Cadherin_2 PF08266.12 CDS28055.1 - 4.1e-07 29.7 0.0 0.00018 21.2 0.0 3.8 3 0 0 3 3 3 1 Cadherin-like RET_CLD1 PF17756.1 CDS28055.1 - 0.055 13.8 0.0 4.8 7.5 0.0 3.4 3 0 0 3 3 3 0 RET Cadherin like domain 1 Peptidase_M60 PF13402.6 CDS28055.1 - 0.2 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like Big_1 PF02369.16 CDS28055.1 - 9 6.4 6.8 33 4.6 0.4 3.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Troponin PF00992.20 CDS28056.1 - 1.7e-09 38.1 59.5 6.1e-09 36.3 12.5 2.4 1 1 1 2 2 2 2 Troponin DUF3153 PF11353.8 CDS28056.1 - 2.9 7.4 5.8 0.48 10.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) Nup84_Nup100 PF04121.13 CDS28057.1 - 1.8e-117 393.3 5.3 8.6e-64 215.9 0.5 2.2 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 RMI1_N PF08585.12 CDS28058.1 - 7.9e-18 65.0 0.1 5.7e-16 58.9 0.1 2.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein UBA PF00627.31 CDS28058.1 - 3.7e-05 23.5 0.1 7.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Cadherin PF00028.17 CDS28059.1 - 9.2e-63 208.7 0.0 7.4e-18 64.8 0.0 8.6 8 0 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.12 CDS28059.1 - 3e-07 30.2 0.7 0.014 15.2 0.0 4.8 5 1 0 5 5 5 2 Cadherin-like Invasin_D3 PF09134.10 CDS28059.1 - 0.082 13.2 0.1 90 3.5 0.0 4.1 4 0 0 4 4 4 0 Invasin, domain 3 DUF773 PF05600.12 CDS28060.1 - 1.7e-112 376.8 7.2 2e-112 376.5 7.2 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 VPS28 PF03997.12 CDS28060.1 - 0.00026 20.7 2.5 0.0081 15.9 0.5 2.5 2 0 0 2 2 2 1 VPS28 protein TPR_MLP1_2 PF07926.12 CDS28060.1 - 0.0085 16.2 13.2 0.2 11.7 0.2 2.9 3 0 0 3 3 2 2 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 CDS28060.1 - 0.014 14.6 5.4 0.1 11.8 0.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein Tektin PF03148.14 CDS28060.1 - 0.016 14.0 10.0 0.41 9.4 1.5 2.6 2 0 0 2 2 2 0 Tektin family Exonuc_VII_L PF02601.15 CDS28060.1 - 0.021 14.4 4.7 1.3 8.5 0.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit HAUS-augmin3 PF14932.6 CDS28060.1 - 0.024 14.2 7.8 0.034 13.7 1.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 CDS28060.1 - 0.025 14.6 16.8 0.078 13.0 4.7 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CREPT PF16566.5 CDS28060.1 - 0.028 14.6 7.3 1.6 8.9 2.1 2.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HemX PF04375.14 CDS28060.1 - 0.034 13.5 5.5 0.55 9.5 0.2 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FCH PF00611.23 CDS28060.1 - 0.051 13.9 0.1 0.25 11.6 0.1 2.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF948 PF06103.11 CDS28060.1 - 0.098 12.9 1.1 1.4 9.2 0.2 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Med21 PF11221.8 CDS28060.1 - 0.12 12.7 0.2 0.12 12.7 0.2 3.1 4 0 0 4 4 3 0 Subunit 21 of Mediator complex SKA1 PF07160.12 CDS28060.1 - 0.13 12.1 7.1 0.73 9.6 0.4 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 GATase_4 PF13230.6 CDS28060.1 - 0.22 10.4 1.4 0.3 9.9 0.2 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II UPF0242 PF06785.11 CDS28060.1 - 0.28 11.3 10.8 2.9 7.9 2.9 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 CDS28060.1 - 0.59 9.9 11.7 0.27 11.0 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator PspA_IM30 PF04012.12 CDS28060.1 - 0.7 9.4 9.7 2 8.0 4.3 2.6 2 0 0 2 2 2 0 PspA/IM30 family DUF1043 PF06295.12 CDS28060.1 - 0.77 9.8 6.6 0.97 9.4 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) SKA2 PF16740.5 CDS28060.1 - 0.85 9.4 10.1 1.1 9.0 2.7 3.2 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Laminin_II PF06009.12 CDS28060.1 - 0.97 9.4 11.0 1.7 8.6 0.6 3.9 4 1 0 4 4 3 0 Laminin Domain II DUF2408 PF10303.9 CDS28060.1 - 0.98 10.0 8.3 1.2 9.7 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DUF3450 PF11932.8 CDS28060.1 - 1.1 8.5 9.9 1 8.6 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 CDS28060.1 - 1.1 9.9 9.0 3.9 8.1 0.9 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4201 PF13870.6 CDS28060.1 - 1.7 8.4 13.9 0.95 9.2 3.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 CDS28060.1 - 1.8 8.9 10.2 4.4 7.7 0.3 2.9 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 CDS28060.1 - 1.9 7.9 15.5 1.1 8.7 1.3 2.6 3 0 0 3 3 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 CDS28060.1 - 2.4 8.4 15.1 4 7.6 1.0 2.7 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) DASH_Dam1 PF08653.10 CDS28060.1 - 2.5 8.0 5.2 1.7 8.5 0.0 3.4 5 0 0 5 5 3 0 DASH complex subunit Dam1 YlqD PF11068.8 CDS28060.1 - 3.4 8.0 7.5 4.2 7.8 2.3 2.6 2 0 0 2 2 2 0 YlqD protein YabA PF06156.13 CDS28060.1 - 3.6 8.3 7.7 15 6.3 2.2 2.9 2 0 0 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 CDS28060.1 - 4.2 6.6 8.8 1.5 8.1 1.2 2.3 2 0 0 2 2 2 0 FAM76 protein FAP206 PF12018.8 CDS28060.1 - 4.2 6.8 10.4 7.3 6.0 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function CENP-H PF05837.12 CDS28060.1 - 5.7 7.4 15.7 3.6 8.0 1.4 3.4 4 0 0 4 4 2 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 CDS28060.1 - 5.9 7.7 10.6 5 7.9 1.7 2.9 3 0 0 3 3 2 0 Occludin homology domain Helicase_C_2 PF13307.6 CDS28061.1 - 9.3e-47 159.4 0.0 9.5e-46 156.1 0.0 2.4 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDS28061.1 - 6.8e-41 139.8 2.8 1.2e-40 138.9 2.8 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CDS28061.1 - 0.00031 20.6 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS28061.1 - 0.00036 20.6 0.5 0.35 10.9 0.1 2.9 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit PhoH PF02562.16 CDS28061.1 - 0.029 13.8 0.0 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 CDS28061.1 - 0.1 11.3 0.0 5.5 5.6 0.0 2.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.6 CDS28061.1 - 0.11 12.8 0.1 5.1 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain LRR_8 PF13855.6 CDS28062.2 - 2.7e-94 308.9 59.4 1.6e-15 56.6 2.8 8.9 6 3 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 CDS28062.2 - 2.8e-34 116.6 62.7 5e-06 26.8 1.6 11.2 6 3 5 12 12 12 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDS28062.2 - 2.1e-28 98.9 12.8 6.1e-11 42.4 4.2 4.9 4 0 0 4 4 4 3 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 CDS28062.2 - 2.8e-25 88.3 124.7 3.6e-07 30.3 6.6 11.5 10 1 0 10 10 10 7 EGF-like domain LRR_9 PF14580.6 CDS28062.2 - 5.7e-20 71.5 25.5 0.0039 16.7 0.2 7.5 5 3 3 8 8 8 8 Leucine-rich repeat Laminin_G_2 PF02210.24 CDS28062.2 - 5.6e-16 59.3 0.0 9.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CDS28062.2 - 1.1e-15 58.0 0.0 1.8e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 CDS28062.2 - 2.6e-15 56.4 108.3 3.7e-07 30.5 9.4 12.2 11 0 0 11 11 8 5 Human growth factor-like EGF LRRNT PF01462.18 CDS28062.2 - 1e-09 37.8 14.8 3e-06 26.7 5.8 10.5 8 2 0 8 8 8 3 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 CDS28062.2 - 1.1e-08 34.4 67.9 0.72 10.6 0.3 17.3 18 0 0 18 18 16 3 Leucine Rich Repeat LRRCT PF01463.24 CDS28062.2 - 5.2e-07 29.7 4.9 0.015 15.8 0.1 6.1 5 0 0 5 5 5 1 Leucine rich repeat C-terminal domain EGF_CA PF07645.15 CDS28062.2 - 0.007 16.6 11.4 0.007 16.6 11.4 10.3 7 2 4 11 11 8 2 Calcium-binding EGF domain DKNYY PF13644.6 CDS28062.2 - 0.071 13.9 0.2 2.3e+02 2.5 0.0 4.8 5 1 1 6 6 5 0 DKNYY family Ion_trans PF00520.31 CDS28063.1 - 1.1e-176 584.9 57.8 3.5e-64 216.4 5.0 3.8 4 0 0 4 4 4 3 Ion transport protein PKD_channel PF08016.12 CDS28063.1 - 4.7e-06 25.5 21.9 4.7e-06 25.5 21.9 6.6 5 2 1 6 6 6 4 Polycystin cation channel Rax2 PF12768.7 CDS28063.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4834 PF16118.5 CDS28063.1 - 0.097 13.6 10.0 13 6.8 0.0 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4834) MLANA PF14991.6 CDS28063.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A DUF2973 PF11189.8 CDS28063.1 - 5.1 7.3 7.2 3.3 7.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2973) Mago-bind PF09282.10 CDS28064.1 - 3.5e-16 58.7 0.9 6.2e-16 58.0 0.9 1.4 1 0 0 1 1 1 1 Mago binding DUF1754 PF08555.10 CDS28064.1 - 7 7.5 11.6 0.99 10.2 5.3 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) TTL PF03133.15 CDS28065.1 - 9.4e-85 284.3 1.8 1.7e-84 283.4 1.8 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDS28065.1 - 4.4e-06 26.1 0.3 0.00051 19.4 0.1 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDS28065.1 - 0.0018 17.6 0.0 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF4763 PF15960.5 CDS28065.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) RPN7 PF10602.9 CDS28066.1 - 5.4e-58 195.5 1.0 9.3e-58 194.8 1.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CDS28066.1 - 2.3e-14 53.8 0.1 7.8e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain eIF3_N PF09440.10 CDS28066.1 - 0.065 13.7 1.0 0.17 12.3 1.0 1.7 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF1400 PF07176.11 CDS28066.1 - 0.066 13.5 0.1 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) EGF PF00008.27 CDS28067.1 - 0.019 15.2 1.4 0.019 15.2 1.4 4.1 3 1 0 3 3 3 0 EGF-like domain zf-A20 PF01754.16 CDS28068.1 - 3.3e-11 42.9 8.3 3.3e-11 42.9 8.3 2.4 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 CDS28068.1 - 4.8e-09 36.2 9.3 4.8e-09 36.2 9.3 2.0 3 0 0 3 3 3 1 AN1-like Zinc finger Carla_C4 PF01623.17 CDS28068.1 - 0.051 13.5 1.0 0.051 13.5 1.0 1.9 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein HEAT PF02985.22 CDS28069.1 - 1.8e-12 46.4 2.6 0.00014 21.8 0.3 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 CDS28069.1 - 3.4e-12 46.6 2.1 0.00062 20.2 0.1 3.2 1 1 2 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.6 CDS28069.1 - 5.3e-12 46.0 0.9 2.7e-05 24.5 0.3 2.4 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.7 CDS28069.1 - 1.4e-10 41.4 0.1 3e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDS28069.1 - 4.9e-08 32.0 0.3 6.5e-05 21.7 0.2 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Arm PF00514.23 CDS28069.1 - 1.1e-07 31.6 1.4 0.0023 17.9 0.0 2.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CDS28069.1 - 0.0024 18.4 0.1 0.0056 17.3 0.1 1.5 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region RICTOR_V PF14668.6 CDS28069.1 - 0.0031 17.7 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 CDS28069.1 - 0.0037 17.4 0.2 0.11 12.6 0.0 2.2 1 1 1 2 2 2 1 V-ATPase subunit H CLASP_N PF12348.8 CDS28069.1 - 0.0069 16.0 0.2 0.086 12.4 0.2 2.3 1 1 1 2 2 2 1 CLASP N terminal Proteasom_PSMB PF10508.9 CDS28069.1 - 0.014 13.9 0.0 0.24 9.9 0.0 1.8 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 CDS28069.1 - 0.032 13.7 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like IFRD PF05004.13 CDS28069.1 - 0.037 13.2 0.7 3.9 6.5 0.0 2.0 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 CDS28069.1 - 0.053 14.2 1.8 9.2 7.3 0.1 3.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat TAF6_C PF07571.13 CDS28069.1 - 0.066 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Nipped-B_C PF12830.7 CDS28069.1 - 0.071 13.0 0.3 11 5.9 0.0 2.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Condensin2nSMC PF12422.8 CDS28069.1 - 0.13 12.5 0.2 2.8 8.1 0.1 2.4 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit PET122 PF05476.11 CDS28070.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 PET122 Dodecin PF07311.12 CDS28070.1 - 0.17 12.1 0.1 1.5 9.1 0.0 2.3 3 0 0 3 3 3 0 Dodecin RVT_1 PF00078.27 CDS28071.1 - 1.9e-19 70.1 0.2 2.4e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gln-synt_C PF00120.24 CDS28072.1 - 3.2e-16 59.3 0.0 1.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CDS28072.1 - 2.1e-13 49.8 0.0 3.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VGCC_alpha2 PF08473.11 CDS28073.1 - 1.1e-23 83.8 2.4 2.1e-21 76.2 2.1 2.3 2 0 0 2 2 2 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.11 CDS28073.1 - 7e-16 58.8 0.3 7e-16 58.8 0.3 2.2 2 0 0 2 2 2 1 VWA N-terminal dCache_1 PF02743.18 CDS28073.1 - 2.9e-10 40.4 1.4 1.3e-07 31.6 0.0 3.6 4 0 0 4 4 4 1 Cache domain VWA_3 PF13768.6 CDS28073.1 - 1.2e-09 38.2 0.0 3.4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDS28073.1 - 6.4e-09 36.3 0.0 1.9e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDS28073.1 - 2.3e-05 25.0 0.2 0.00023 21.8 0.2 2.6 1 1 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 CDS28073.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Homeodomain PF00046.29 CDS28074.1 - 6.4e-19 67.5 6.7 1.2e-18 66.7 6.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 CDS28076.1 - 6.6e-21 73.9 10.4 6.6e-21 73.9 10.4 1.8 2 0 0 2 2 2 1 Homeodomain DUF2209 PF09974.9 CDS28076.1 - 0.062 13.6 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Guanylate_kin PF00625.21 CDS28077.1 - 7.9e-27 94.1 0.0 1.5e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.24 CDS28077.1 - 2.4e-06 27.8 0.1 7.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDS28077.1 - 4e-06 26.6 0.1 9.9e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS28077.1 - 0.00011 21.7 0.1 0.00056 19.5 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CDS28077.1 - 0.00033 20.3 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 CDS28077.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 CDS28077.1 - 0.05 13.4 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 L27 domain SH3_9 PF14604.6 CDS28077.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain RUN PF02759.19 CDS28078.1 - 1e-13 51.4 0.1 2.3e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 RUN domain AdoMet_MTase PF07757.13 CDS28079.2 - 7.4e-76 251.7 0.2 9.5e-41 138.6 0.1 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CDS28079.2 - 3.6e-07 30.1 0.0 0.038 13.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.6 CDS28079.2 - 6e-07 29.6 0.4 0.2 11.6 0.0 3.8 4 0 0 4 4 4 2 Methyltransferase domain MetW PF07021.12 CDS28079.2 - 2.4e-06 27.3 0.0 0.093 12.3 0.0 2.4 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 CDS28079.2 - 1.1e-05 25.3 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CDS28079.2 - 4.7e-05 23.0 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 CDS28079.2 - 9.9e-05 23.0 0.0 0.94 10.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDS28079.2 - 0.00011 22.9 0.0 0.96 10.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CDS28079.2 - 0.0064 17.1 0.0 7.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain PqqA PF08042.11 CDS28079.2 - 0.009 16.0 0.3 7.4 6.8 0.0 2.6 2 0 0 2 2 2 2 PqqA family TehB PF03848.14 CDS28079.2 - 0.014 14.8 0.0 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 CDS28079.2 - 0.078 12.4 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase DUF2207 PF09972.9 CDS28080.1 - 0.033 13.0 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CYYR1 PF10873.8 CDS28080.1 - 0.034 14.6 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 K1 PF02960.14 CDS28080.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 K1 glycoprotein Transposase_1 PF01359.18 CDS28081.1 - 1.6e-18 66.3 0.1 3.6e-18 65.1 0.1 1.6 1 1 0 1 1 1 1 Transposase (partial DDE domain) AAA_2 PF07724.14 CDS28082.1 - 2.6e-43 148.1 0.0 4.1e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 CDS28082.1 - 3.3e-15 56.4 0.0 4.9e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDS28082.1 - 3.9e-15 55.5 0.0 4e-06 27.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDS28082.1 - 3.8e-12 45.2 0.1 0.00018 21.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat AAA_5 PF07728.14 CDS28082.1 - 2.4e-10 40.6 0.0 1.5e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDS28082.1 - 2.8e-09 36.9 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CDS28082.1 - 1.6e-08 35.0 0.0 2.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 CDS28082.1 - 3.8e-08 33.7 0.4 0.035 14.7 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS28082.1 - 4.4e-08 33.2 0.4 0.0027 18.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.9 CDS28082.1 - 2.6e-07 30.6 0.0 8.8e-07 28.9 0.0 1.9 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_3 PF07726.11 CDS28082.1 - 2.3e-05 24.2 0.0 0.0018 18.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 CDS28082.1 - 4.6e-05 23.5 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Torsin Zeta_toxin PF06414.12 CDS28082.1 - 4.9e-05 22.7 0.0 8.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 CDS28082.1 - 0.0009 19.5 0.0 0.013 15.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDS28082.1 - 0.00095 19.6 0.0 0.019 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CDS28082.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS28082.1 - 0.0083 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS28082.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS28082.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CDS28082.1 - 0.088 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CDS28082.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 CDS28082.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain UCH PF00443.29 CDS28083.2 - 5.3e-11 42.5 0.0 1.9e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS28083.2 - 1.3e-07 31.6 0.9 6.8e-06 25.9 0.4 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HJURP_C PF12347.8 CDS28083.2 - 0.033 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat RRM_1 PF00076.22 CDS28084.1 - 4.1e-17 61.7 0.0 5.4e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28084.1 - 6.5e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC PF00098.23 CDS28084.1 - 7.5e-05 22.6 4.7 0.00013 21.9 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDS28084.1 - 0.00034 20.5 1.7 0.00052 19.9 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 CDS28084.1 - 0.00078 19.0 0.0 0.00096 18.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_5 PF14787.6 CDS28084.1 - 0.0078 15.9 2.4 0.014 15.1 2.4 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger VRR_NUC PF08774.11 CDS28085.1 - 2.1e-22 79.2 0.0 8.8e-22 77.2 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain TPH PF13868.6 CDS28087.1 - 1e-56 192.0 116.1 1e-56 192.0 116.1 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain EIF_2_alpha PF07541.12 CDS28087.1 - 0.024 14.7 1.0 0.024 14.7 1.0 3.2 3 2 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit Tropomyosin PF00261.20 CDS28088.1 - 4.9e-89 297.8 74.7 1.4e-86 289.7 51.8 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CDS28088.1 - 2.8e-31 108.6 65.0 5e-29 101.3 32.9 3.0 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.12 CDS28088.1 - 8.3e-05 22.6 37.1 0.031 14.3 3.6 4.1 1 1 3 4 4 4 2 Laminin Domain II ERM PF00769.19 CDS28088.1 - 0.00024 21.0 24.3 0.00024 21.0 24.3 2.9 1 1 0 2 2 2 1 Ezrin/radixin/moesin family HrpB7 PF09486.10 CDS28088.1 - 0.00032 21.1 43.8 0.071 13.5 10.0 3.7 1 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 CDS28088.1 - 0.00096 19.7 49.3 0.027 14.9 20.6 2.2 1 1 1 2 2 2 2 Fez1 MscS_porin PF12795.7 CDS28088.1 - 0.001 18.6 39.1 0.024 14.2 7.1 3.0 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain BST2 PF16716.5 CDS28088.1 - 0.011 16.3 37.6 0.027 15.0 5.0 4.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 GAS PF13851.6 CDS28088.1 - 0.02 14.3 45.2 0.015 14.6 16.9 3.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 CDS28088.1 - 0.021 15.2 42.6 0.17 12.2 7.5 5.3 2 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 CDS28088.1 - 0.021 15.3 33.0 1.2 9.7 7.9 4.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 Rab5-bind PF09311.11 CDS28088.1 - 0.022 14.2 43.2 0.02 14.3 8.7 3.2 1 1 2 3 3 3 0 Rabaptin-like protein NPV_P10 PF05531.12 CDS28088.1 - 0.05 14.1 15.0 0.2 12.2 0.8 4.5 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 CDS28088.1 - 0.068 11.4 49.9 0.27 9.4 24.6 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Alanine_zipper PF11839.8 CDS28088.1 - 0.07 13.5 29.0 0.22 11.9 2.2 4.8 4 1 0 4 4 3 0 Alanine-zipper, major outer membrane lipoprotein EzrA PF06160.12 CDS28088.1 - 0.08 11.1 39.3 0.28 9.3 3.9 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA T3SSipB PF16535.5 CDS28088.1 - 0.087 13.3 35.2 2.1 8.8 1.9 3.7 1 1 3 4 4 4 0 Type III cell invasion protein SipB FOXP-CC PF16159.5 CDS28088.1 - 0.11 13.2 0.2 0.11 13.2 0.2 3.7 3 2 0 3 3 3 0 FOXP coiled-coil domain DUF724 PF05266.14 CDS28088.1 - 0.12 12.1 48.3 0.046 13.5 14.9 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF3138 PF11336.8 CDS28088.1 - 0.15 10.7 5.7 0.081 11.5 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Lebercilin PF15619.6 CDS28088.1 - 0.16 11.6 53.3 3.3 7.3 14.0 4.1 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BicD PF09730.9 CDS28088.1 - 0.17 10.3 43.6 0.11 10.9 9.8 2.9 1 1 2 3 3 3 0 Microtubule-associated protein Bicaudal-D Fib_alpha PF08702.10 CDS28088.1 - 0.22 11.7 28.6 0.92 9.7 4.3 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CDS28088.1 - 0.29 10.0 50.0 0.043 12.7 19.0 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CDS28088.1 - 0.33 11.0 59.8 0.37 10.9 17.8 4.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CDS28088.1 - 0.33 9.5 41.1 0.068 11.8 5.2 2.6 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 CDS28088.1 - 0.39 10.8 14.8 0.59 10.2 2.5 3.7 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 CDS28088.1 - 0.46 10.0 46.3 0.49 9.9 9.8 3.1 1 1 3 4 4 4 0 Intermediate filament protein BLOC1_2 PF10046.9 CDS28088.1 - 0.5 10.7 31.9 4.9 7.5 5.9 4.4 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 CDS28088.1 - 0.51 7.8 43.7 0.78 7.2 43.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TolA_bind_tri PF16331.5 CDS28088.1 - 0.57 10.3 30.6 0.53 10.4 3.7 5.0 2 2 3 5 5 5 0 TolA binding protein trimerisation Vac_Fusion PF02346.16 CDS28088.1 - 0.62 9.7 13.9 1.4 8.6 0.6 4.8 3 2 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 ATG16 PF08614.11 CDS28088.1 - 0.62 10.3 57.4 2.1 8.6 17.7 3.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CDS28088.1 - 0.82 9.2 34.2 2.5 7.6 13.5 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF745 PF05335.13 CDS28088.1 - 0.98 9.1 38.8 1.2 8.8 9.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 CDS28088.1 - 1.1 8.5 44.0 0.54 9.5 14.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 CDS28088.1 - 1.1 9.6 58.9 1.7 9.0 9.8 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) KxDL PF10241.9 CDS28088.1 - 1.2 9.5 29.1 0.46 10.8 1.0 4.6 2 1 3 5 5 5 0 Uncharacterized conserved protein IFT57 PF10498.9 CDS28088.1 - 1.4 7.8 39.9 0.046 12.7 11.7 3.5 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 Laminin_I PF06008.14 CDS28088.1 - 1.6 8.3 42.0 0.17 11.6 10.6 3.2 1 1 2 3 3 3 0 Laminin Domain I ADIP PF11559.8 CDS28088.1 - 1.7 8.7 46.3 1.6 8.8 11.4 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding AATF-Che1 PF13339.6 CDS28088.1 - 1.8 9.2 32.0 3e+02 2.0 20.4 3.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor HOOK PF05622.12 CDS28088.1 - 1.8 6.6 50.1 1.8e+02 -0.0 50.1 2.9 1 1 0 1 1 1 0 HOOK protein Golgin_A5 PF09787.9 CDS28088.1 - 1.9 7.9 52.5 0.083 12.4 19.7 2.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CDS28088.1 - 2.4 8.2 28.4 2.6 8.1 2.1 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 CDS28088.1 - 2.6 8.4 57.1 23 5.4 15.5 3.9 1 1 1 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CALCOCO1 PF07888.11 CDS28088.1 - 2.7 6.8 53.1 2.9 6.7 16.2 2.7 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cast PF10174.9 CDS28088.1 - 2.7 6.1 48.8 5.1 5.2 33.5 2.0 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone XhlA PF10779.9 CDS28088.1 - 3.1 8.1 45.5 0.39 11.0 3.0 6.2 2 1 4 6 6 6 0 Haemolysin XhlA Uds1 PF15456.6 CDS28088.1 - 3.6 7.8 46.1 0.92 9.7 10.4 3.4 1 1 2 3 3 3 0 Up-regulated During Septation DUF4407 PF14362.6 CDS28088.1 - 4.3 6.6 41.4 2.7 7.3 6.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 CDS28088.1 - 4.5 6.0 52.6 2.1 7.1 21.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF948 PF06103.11 CDS28088.1 - 4.7 7.5 20.9 7.5 6.9 0.5 4.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MAD PF05557.13 CDS28088.1 - 4.8 5.4 52.0 0.14 10.5 22.4 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Mod_r PF07200.13 CDS28088.1 - 5 7.2 46.5 1.1 9.3 12.2 3.5 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4472 PF14739.6 CDS28088.1 - 6.3 7.6 45.8 0.87 10.4 12.6 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) UCH PF00443.29 CDS28089.1 - 1.1e-63 215.2 0.2 1.8e-63 214.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS28089.1 - 3.6e-13 49.8 4.0 9.2e-12 45.2 4.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CDS28089.1 - 0.016 15.7 0.0 0.038 14.5 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain zf-HIT PF04438.16 CDS28089.1 - 0.35 10.8 2.2 2.7 8.0 0.3 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-MYND PF01753.18 CDS28089.1 - 0.88 9.7 5.5 0.13 12.4 0.7 2.2 2 0 0 2 2 2 0 MYND finger Tetraspanin PF00335.20 CDS28090.1 - 2.4e-28 99.4 19.3 3.2e-28 99.0 19.3 1.1 1 0 0 1 1 1 1 Tetraspanin family ALMT PF11744.8 CDS28090.1 - 1.8 7.3 4.8 2.5 6.8 4.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EVC2_like PF12297.8 CDS28090.1 - 2.8 6.5 4.4 2 7.0 2.1 1.8 1 1 1 2 2 2 0 Ellis van Creveld protein 2 like protein DUF2207 PF09972.9 CDS28090.1 - 9 4.9 15.3 12 4.5 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) UQ_con PF00179.26 CDS28091.1 - 1.4e-43 147.9 0.1 2e-43 147.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS28091.1 - 0.039 13.7 0.1 0.38 10.4 0.1 2.2 1 1 0 1 1 1 0 Prokaryotic E2 family B zf-HC5HC2H_2 PF13832.6 CDS28092.1 - 5.5e-19 68.3 4.6 5.5e-19 68.3 4.6 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDS28092.1 - 1.2e-09 38.3 4.4 1.2e-09 38.3 4.4 3.7 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDS28092.1 - 7.6e-07 28.6 1.9 7.6e-07 28.6 1.9 3.3 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 CDS28092.1 - 0.0002 21.2 5.9 0.0002 21.2 5.9 3.5 2 1 0 2 2 2 2 PHD-finger CEBP_ZZ PF16366.5 CDS28092.1 - 0.026 14.7 0.7 0.026 14.7 0.7 3.8 2 1 1 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AT_hook PF02178.19 CDS28092.1 - 0.04 13.8 1.6 0.19 11.7 1.6 2.2 1 0 0 1 1 1 0 AT hook motif HALZ PF02183.18 CDS28092.1 - 0.29 11.4 3.5 0.65 10.3 3.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIVA PF05103.13 CDS28092.1 - 0.78 9.8 5.8 1.5 8.9 0.8 2.6 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.15 CDS28092.1 - 1.7 8.5 4.9 0.26 11.1 0.4 2.0 2 0 0 2 2 2 0 Septum formation initiator C1_2 PF03107.16 CDS28092.1 - 7.5 7.0 26.6 0.84 10.0 4.9 4.3 3 1 0 3 3 3 0 C1 domain Ank_2 PF12796.7 CDS28095.1 - 1.3e-50 169.9 6.4 1.9e-16 60.4 0.1 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 CDS28095.1 - 3e-31 106.5 8.4 7.2e-07 29.4 0.1 8.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 CDS28095.1 - 1.1e-28 99.3 0.7 2.7e-10 40.5 0.1 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28095.1 - 3.4e-28 94.6 3.6 0.0013 19.0 0.1 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 CDS28095.1 - 5.6e-24 83.9 5.5 9.1e-05 22.7 0.0 7.0 2 2 7 9 9 9 5 Ankyrin repeats (many copies) DapH_N PF08503.10 CDS28095.1 - 0.031 14.5 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal YpsA PF06908.11 CDS28096.1 - 0.019 15.0 0.2 0.16 11.9 0.0 2.3 3 0 0 3 3 3 0 YspA SLOG family ACDC PF14733.6 CDS28096.1 - 0.024 14.9 0.2 0.18 12.1 0.1 2.2 2 0 0 2 2 2 0 AP2-coincident C-terminal Ank_2 PF12796.7 CDS28098.1 - 6.7e-25 87.5 0.4 2.1e-20 73.1 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS28098.1 - 1.3e-23 83.0 0.8 1.6e-12 47.6 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28098.1 - 4e-20 69.8 0.3 9.2e-08 31.8 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDS28098.1 - 8.4e-19 67.4 0.8 1.3e-10 41.3 0.1 3.4 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS28098.1 - 1.6e-16 59.9 2.3 1.8e-07 31.3 0.0 4.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 CDS28099.1 - 1.3e-08 35.3 0.1 1.9e-07 31.6 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS28099.1 - 3.8e-07 29.9 0.0 0.39 11.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDS28099.1 - 4.4e-07 30.3 0.0 0.00035 21.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS28099.1 - 5.3e-05 23.4 0.1 0.0005 20.3 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CDS28099.1 - 0.00095 19.5 0.0 6.5 7.4 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat Runt PF00853.19 CDS28100.1 - 1.2e-58 196.2 0.0 2.1e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Runt domain Fmp27_SW PF10305.9 CDS28100.1 - 0.038 14.7 0.1 5.3 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Runt PF00853.19 CDS28101.1 - 7.1e-58 193.8 0.0 1.2e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Runt domain eIF2_C PF09173.11 CDS28104.1 - 2e-36 124.1 0.4 4.9e-36 122.8 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CDS28104.1 - 1.8e-23 83.1 2.6 1.1e-22 80.5 2.6 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDS28104.1 - 5.7e-11 42.6 0.3 1.4e-10 41.4 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CDS28104.1 - 0.0045 16.9 0.5 0.011 15.6 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CDS28104.1 - 0.021 14.8 1.5 0.053 13.5 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CDS28104.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ASXH PF13919.6 CDS28105.1 - 1.4e-15 57.5 0.2 1.2e-14 54.5 0.1 2.6 2 0 0 2 2 2 1 Asx homology domain MarB PF13999.6 CDS28105.1 - 0.36 10.7 3.9 3.3 7.6 0.3 3.4 3 0 0 3 3 3 0 MarB protein EF-hand_1 PF00036.32 CDS28106.1 - 1.5e-42 140.0 9.9 7.5e-10 37.6 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS28106.1 - 1.7e-35 121.3 2.6 6.4e-18 65.0 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDS28106.1 - 9.6e-35 118.2 10.6 4.8e-16 58.4 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDS28106.1 - 2e-30 102.1 5.2 1.3e-09 37.2 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS28106.1 - 1.4e-26 90.8 7.6 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDS28106.1 - 4.2e-16 59.0 0.2 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDS28106.1 - 2.7e-10 40.1 0.5 7.7e-05 22.6 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS28106.1 - 6.2e-08 33.0 0.0 0.0079 16.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDS28106.1 - 3.2e-07 31.2 0.0 0.00015 22.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CDS28106.1 - 1.5e-05 24.9 0.0 0.065 13.3 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CDS28106.1 - 0.00046 20.3 4.5 0.11 12.7 0.5 2.9 1 1 2 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 CDS28106.1 - 0.00067 19.6 0.3 0.26 11.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 CDS28106.1 - 0.00098 19.2 0.7 0.0068 16.5 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 CDS28106.1 - 0.0012 18.5 2.0 0.0014 18.3 2.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 CDS28106.1 - 0.0013 19.5 0.4 1.2 9.9 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 CDS28106.1 - 0.0018 18.7 0.0 0.91 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) RNA_pol_Rpb4 PF03874.16 CDS28106.1 - 0.0018 18.6 0.9 1.8 8.9 0.2 2.6 3 0 0 3 3 2 2 RNA polymerase Rpb4 TerB PF05099.13 CDS28106.1 - 0.0018 18.2 0.4 1 9.3 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 CDS28106.1 - 0.0075 14.9 0.0 0.0075 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 CDS28106.1 - 0.013 15.3 0.6 0.43 10.4 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Poly_export PF02563.16 CDS28106.1 - 0.015 15.5 0.0 0.57 10.4 0.0 2.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein dCache_2 PF08269.11 CDS28106.1 - 0.023 13.9 0.1 1.9 7.6 0.0 2.1 1 1 0 2 2 2 0 Cache domain SurA_N_3 PF13624.6 CDS28106.1 - 0.026 14.3 0.4 0.34 10.7 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF2267 PF10025.9 CDS28106.1 - 0.033 14.5 0.0 0.14 12.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) EF-hand_14 PF17959.1 CDS28106.1 - 0.033 14.5 0.1 9.8 6.6 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF853 PF05872.12 CDS28106.1 - 0.034 12.8 0.1 0.93 8.0 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) TetR_C_7 PF14246.6 CDS28106.1 - 0.035 14.1 0.0 6.8 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 CDS28106.1 - 0.077 13.1 0.3 0.19 11.8 0.3 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MotA_activ PF09114.10 CDS28106.1 - 0.1 12.8 0.3 1.7 8.8 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain CMD PF02627.20 CDS28106.1 - 0.18 11.8 0.4 7.3 6.7 0.0 2.8 3 1 1 4 4 4 0 Carboxymuconolactone decarboxylase family SapB_1 PF05184.15 CDS28106.1 - 0.33 11.0 1.1 43 4.3 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 ThiF PF00899.21 CDS28109.1 - 1.9e-78 263.2 0.0 6.5e-40 137.0 0.0 3.4 3 1 0 3 3 3 3 ThiF family UBA_e1_thiolCys PF10585.9 CDS28109.1 - 1.5e-40 139.7 0.0 2.1e-35 122.9 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CDS28109.1 - 6.6e-16 58.3 0.2 1.5e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CDS28109.1 - 1.1e-09 38.3 0.5 3.6e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 CDS28109.1 - 6.7e-07 29.9 0.0 2.7e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin fold domain 2-Hacid_dh_C PF02826.19 CDS28109.1 - 0.075 12.4 0.0 1 8.7 0.0 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EF-hand_1 PF00036.32 CDS28110.1 - 9.9e-31 103.0 7.8 3.4e-08 32.5 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS28110.1 - 1.8e-25 89.2 1.9 8e-15 55.1 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS28110.1 - 2.2e-24 83.8 5.9 2.6e-06 26.7 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS28110.1 - 6.4e-24 81.8 3.9 1.3e-06 27.8 0.0 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CDS28110.1 - 1.5e-22 79.2 8.3 2.2e-10 40.2 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDS28110.1 - 2.5e-07 30.9 0.1 7.8e-06 26.1 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS28110.1 - 6.8e-05 23.1 0.1 0.037 14.3 0.0 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS28110.1 - 0.00035 20.5 0.7 0.87 9.6 0.1 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CDS28110.1 - 0.0011 19.0 0.1 0.037 14.1 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CDS28110.1 - 0.0014 18.7 4.1 0.49 10.6 0.1 3.1 2 2 2 4 4 4 2 Dockerin type I domain DUF892 PF05974.12 CDS28110.1 - 0.018 15.0 0.3 6.5 6.8 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF892) DUF1296 PF06972.11 CDS28110.1 - 0.023 14.8 3.7 0.11 12.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1296) Chrome_Resist PF09828.9 CDS28110.1 - 0.15 12.5 0.4 0.8 10.1 0.1 2.1 2 1 1 3 3 3 0 Chromate resistance exported protein Pou PF00157.17 CDS28112.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDS28112.1 - 0.00081 19.2 0.6 0.0019 18.0 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 CDS28113.1 - 5.7e-35 120.9 0.0 7e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28113.1 - 5.8e-18 65.1 0.0 4.8e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS28113.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FeoA PF04023.14 CDS28113.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 FeoA domain Kdo PF06293.14 CDS28113.1 - 0.12 11.7 0.2 0.26 10.6 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_5 PF13854.6 CDS28115.1 - 2.3e-15 56.2 1.1 4.8e-05 23.2 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CDS28115.1 - 9.4e-15 53.9 0.7 9.1e-05 22.0 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CDS28115.1 - 1.8e-12 47.1 2.7 0.00069 19.6 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDS28115.1 - 6.1e-12 45.4 1.4 0.00029 21.0 0.0 6.0 4 1 2 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CDS28115.1 - 1e-11 44.3 0.3 7e-06 25.8 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CDS28115.1 - 4.1e-08 33.3 0.5 0.56 10.6 0.0 6.4 7 0 0 7 7 7 2 Galactose oxidase, central domain LON_substr_bdg PF02190.16 CDS28116.2 - 0.024 14.5 0.0 0.19 11.6 0.0 2.1 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain TFCD_C PF12612.8 CDS28117.2 - 2e-50 171.3 3.5 1.9e-47 161.5 0.2 4.1 4 0 0 4 4 4 2 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CDS28117.2 - 1.5e-08 34.9 6.6 0.33 11.4 0.0 6.8 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.22 CDS28117.2 - 2.1e-06 27.5 29.7 4.4 7.8 0.0 11.5 13 0 0 13 13 13 2 HEAT repeat Rif1_N PF12231.8 CDS28117.2 - 0.0021 17.1 0.1 0.013 14.5 0.0 2.2 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Cnd1 PF12717.7 CDS28117.2 - 0.0041 17.2 0.1 63 3.6 0.0 5.4 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDS28117.2 - 0.006 15.2 0.3 2 6.9 0.0 4.4 5 0 0 5 5 5 1 Adaptin N terminal region DNA_pol_lambd_f PF10391.9 CDS28117.2 - 0.021 14.6 0.1 16 5.4 0.0 3.2 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda OTT_1508_deam PF14441.6 CDS28117.2 - 0.17 11.9 8.7 3.9 7.6 1.2 2.7 2 0 0 2 2 2 0 OTT_1508-like deaminase Peptidase_C1 PF00112.23 CDS28117.2 - 0.2 11.7 7.0 4.3 7.4 0.8 2.3 2 0 0 2 2 2 0 Papain family cysteine protease AAA_lid_3 PF17862.1 CDS28117.2 - 4 7.3 6.5 4.7 7.1 0.0 3.2 4 0 0 4 4 4 0 AAA+ lid domain Tma16 PF11176.8 CDS28118.2 - 1.5e-29 102.8 7.1 1.6e-29 102.6 7.1 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF4628 PF15429.6 CDS28118.2 - 0.071 12.8 4.7 0.56 9.8 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4628) DEC-1_N PF04625.13 CDS28118.2 - 0.088 11.8 2.7 0.11 11.5 2.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M41 PF01434.18 CDS28120.1 - 2.8e-61 206.7 0.0 4e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDS28120.1 - 1.2e-45 155.1 0.0 2.1e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS28120.1 - 3e-13 49.4 1.6 4.8e-13 48.7 0.4 2.0 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 CDS28120.1 - 1.5e-06 28.6 0.1 3.2e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 CDS28120.1 - 0.0011 19.0 0.0 0.0063 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS28120.1 - 0.0044 17.3 0.0 0.87 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDS28120.1 - 0.011 15.0 1.0 0.015 14.5 0.1 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain RuvB_N PF05496.12 CDS28120.1 - 0.014 15.1 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDS28120.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CDS28120.1 - 0.1 13.0 0.6 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain UBA PF00627.31 CDS28120.1 - 0.11 12.5 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 UBA/TS-N domain AAA_16 PF13191.6 CDS28120.1 - 0.11 12.8 2.9 0.69 10.3 0.1 3.0 3 1 0 4 4 4 0 AAA ATPase domain IstB_IS21 PF01695.17 CDS28120.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein WD40 PF00400.32 CDS28121.1 - 3.1e-18 65.8 15.6 9.8e-05 23.1 0.3 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28121.1 - 1.1e-09 38.4 1.1 5.6e-05 23.4 0.1 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS28121.1 - 2.1e-05 24.5 1.1 0.00037 20.4 0.2 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.19 CDS28122.1 - 3.9e-31 108.7 41.7 3.3e-30 105.6 41.7 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CDS28122.1 - 0.0028 17.9 3.4 0.011 16.0 3.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Lactamase_B PF00753.27 CDS28123.1 - 1.7e-17 64.1 0.9 2.3e-14 53.9 0.3 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDS28123.1 - 3.1e-05 23.6 0.2 4.1e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDS28123.1 - 0.051 13.5 0.2 0.092 12.6 0.2 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CDS28123.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain UQ_con PF00179.26 CDS28124.1 - 1.2e-17 63.9 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDS28124.1 - 0.0043 17.3 0.0 0.005 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 CDS28125.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDS28125.1 - 0.0025 18.1 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Tubulin PF00091.25 CDS28126.1 - 1.4e-67 227.7 0.0 3.5e-67 226.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS28126.1 - 6e-42 142.8 0.0 1.1e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS28126.1 - 1.8e-06 28.3 0.0 4.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDS28126.1 - 0.0061 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Tubulin PF00091.25 CDS28127.1 - 5e-70 235.7 0.0 8e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS28127.1 - 5.3e-43 146.2 0.1 8.6e-43 145.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS28127.1 - 6.2e-06 26.5 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS28127.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS28127.1 - 0.028 13.6 0.1 0.061 12.5 0.0 1.5 2 0 0 2 2 2 0 Tubulin like vATP-synt_AC39 PF01992.16 CDS28128.1 - 1.5e-111 373.1 0.3 1.7e-111 373.0 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF4200 PF13863.6 CDS28129.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3263 PF11662.8 CDS28129.1 - 0.12 12.3 0.5 2.4 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3263) PITH PF06201.13 CDS28130.1 - 1.2e-40 139.2 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain Pkinase_Tyr PF07714.17 CDS28131.2 - 2.5e-160 531.7 0.0 6.7e-79 264.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS28131.2 - 7.4e-84 281.2 0.0 1.8e-39 135.7 0.0 4.0 4 0 0 4 4 4 2 Protein kinase domain Furin-like PF00757.20 CDS28131.2 - 6.8e-27 94.2 90.4 2.6e-17 63.1 22.9 5.9 4 1 1 5 5 5 5 Furin-like cysteine rich region GF_recep_IV PF14843.6 CDS28131.2 - 2.9e-24 85.4 87.4 7.3e-06 25.8 20.5 8.8 7 2 2 9 9 9 7 Growth factor receptor domain IV Recep_L_domain PF01030.24 CDS28131.2 - 2.1e-10 40.7 0.1 1.4e-09 38.0 0.0 2.4 3 0 0 3 3 3 1 Receptor L domain APH PF01636.23 CDS28131.2 - 2e-09 37.7 0.4 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS28131.2 - 7.5e-07 28.7 0.1 0.044 13.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CDS28131.2 - 1.4e-05 24.6 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS28131.2 - 6.1e-05 22.0 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CDS28131.2 - 0.0022 17.0 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain 17kDa_Anti_2 PF16998.5 CDS28131.2 - 0.0022 17.9 0.6 3.1 7.7 0.1 2.6 2 0 0 2 2 2 2 17 kDa outer membrane surface antigen RIO1 PF01163.22 CDS28131.2 - 0.0051 16.4 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 2 RIO1 family SWIRM PF04433.17 CDS28131.2 - 0.019 15.3 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 SWIRM domain RuvC_III PF18541.1 CDS28131.2 - 0.024 14.6 0.0 9.9 6.1 0.0 2.3 2 0 0 2 2 2 0 RuvC endonuclease subdomain 3 YwpF PF14183.6 CDS28131.2 - 0.056 13.4 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 YwpF-like protein LRR_5 PF13306.6 CDS28131.2 - 0.058 13.4 0.0 38 4.3 0.0 3.2 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PCI PF01399.27 CDS28131.2 - 0.21 12.1 0.0 67 4.1 0.0 3.1 4 0 0 4 4 2 0 PCI domain DUF1644 PF07800.12 CDS28132.1 - 0.0066 16.5 1.1 4 7.5 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) zf-C2H2_3rep PF18868.1 CDS28132.1 - 0.079 13.6 3.9 3.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CHCC PF10276.9 CDS28132.1 - 0.14 12.2 1.4 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.15 CDS28132.1 - 0.17 11.8 2.2 1.1 9.3 0.2 3.0 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 CDS28132.1 - 0.59 10.2 15.8 0.84 9.7 3.9 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CDS28132.1 - 0.64 9.5 3.3 15 5.2 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 CDS28132.1 - 4.2 7.8 8.9 0.39 11.1 0.6 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 CDS28132.1 - 4.6 8.0 9.5 0.56 11.0 1.1 3.0 3 0 0 3 3 3 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 CDS28132.1 - 6.2 6.4 7.4 1.8 8.2 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding Desulfoferrod_N PF06397.12 CDS28132.1 - 6.4 6.5 6.9 10 5.9 0.2 3.5 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain Phage_SSB PF16773.5 CDS28133.1 - 0.032 14.3 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein DUF3750 PF12570.8 CDS28133.1 - 0.18 12.5 3.8 0.64 10.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3750) SH3BGR PF04908.15 CDS28134.1 - 6e-24 84.1 0.1 6.5e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CDS28134.1 - 0.00069 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin fn3 PF00041.21 CDS28135.1 - 2.6e-43 146.3 4.2 1.3e-11 44.7 0.5 6.6 6 0 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDS28135.1 - 1.5e-09 38.3 3.5 1.1 9.8 0.0 6.3 6 0 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain Neogenin_C PF06583.12 CDS28135.1 - 5.3e-06 26.5 7.5 5.3e-06 26.5 7.5 3.0 2 1 0 2 2 2 1 Neogenin C-terminus Interfer-bind PF09294.10 CDS28135.1 - 1.1e-05 25.7 0.0 0.038 14.3 0.1 4.3 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III GPI-anchored PF10342.9 CDS28135.1 - 0.0017 19.0 0.7 7.5 7.4 0.0 4.0 4 0 0 4 4 4 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2369 PF10179.9 CDS28135.1 - 0.0019 18.6 0.1 14 6.2 0.1 5.0 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) TMEM154 PF15102.6 CDS28135.1 - 0.015 15.2 1.3 0.056 13.3 1.3 2.0 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 CDS28135.1 - 1 9.5 4.5 0.36 11.0 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ig_3 PF13927.6 CDS28136.2 - 1.9e-06 28.4 0.0 3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS28136.2 - 2.1e-05 24.6 0.0 2.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 CDS28136.2 - 8.9e-05 22.0 0.0 0.00028 20.4 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CDS28136.2 - 0.0002 21.4 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS28136.2 - 0.013 15.8 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain DUF126 PF01989.16 CDS28136.2 - 0.039 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Aconitase X swivel domain V-set PF07686.17 CDS28136.2 - 0.12 12.6 0.1 0.33 11.1 0.1 1.9 1 1 0 1 1 1 0 Immunoglobulin V-set domain ERM PF00769.19 CDS28139.1 - 0.0051 16.7 14.6 0.0051 16.7 14.6 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DNA_gyraseB PF00204.25 CDS28139.1 - 0.052 13.0 1.8 0.084 12.4 0.9 1.8 1 1 0 1 1 1 0 DNA gyrase B SpecificRecomb PF10136.9 CDS28139.1 - 0.33 9.2 13.5 0.21 9.9 9.8 1.9 1 1 1 2 2 2 0 Site-specific recombinase DUF5631 PF18645.1 CDS28139.1 - 1.4 9.4 3.8 16 6.0 0.1 3.2 2 1 0 3 3 3 0 Family of unknown function (DUF5631) TMF_DNA_bd PF12329.8 CDS28139.1 - 1.8 8.6 40.7 0.98 9.5 8.5 5.0 4 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding SIKE PF05769.11 CDS28139.1 - 2.9 7.8 23.9 1.6 8.6 13.5 2.9 2 1 1 3 3 3 0 SIKE family CorA PF01544.18 CDS28139.1 - 3.6 6.8 14.4 1.2 8.4 0.2 2.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein XLF PF09302.11 CDS28139.1 - 4.1 7.5 15.7 0.47 10.6 7.4 3.0 2 2 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Rx_N PF18052.1 CDS28139.1 - 4.1 7.7 15.9 9.6 6.6 5.3 4.5 3 1 1 4 4 4 0 Rx N-terminal domain DUF4407 PF14362.6 CDS28139.1 - 5.8 6.2 29.1 1.7 7.9 4.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CDS28139.1 - 8.7 5.8 25.6 1.8e+03 -1.8 25.6 2.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit TSC22 PF01166.18 CDS28139.1 - 8.8 6.7 14.6 38 4.7 0.1 4.8 4 1 1 5 5 5 0 TSC-22/dip/bun family DUF4140 PF13600.6 CDS28139.1 - 8.8 6.8 24.1 1.3 9.5 2.4 4.9 1 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4042 PF13251.6 CDS28140.1 - 6.1e-21 74.9 0.6 6.1e-21 74.9 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) HCO3_cotransp PF00955.21 CDS28141.2 - 7.4e-224 744.3 1.4 9.9e-224 743.8 1.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 CDS28141.2 - 4.4e-75 253.0 0.9 4.4e-75 253.0 0.9 2.0 2 0 0 2 2 2 1 Band 3 cytoplasmic domain PAP_assoc PF03828.19 CDS28142.1 - 5.3e-08 33.0 0.1 1.2e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDS28142.1 - 0.00057 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDS28142.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF4813 PF16072.5 CDS28143.1 - 0.069 12.8 0.1 0.069 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF4661 PF15576.6 CDS28144.2 - 0.11 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Transposase_1 PF01359.18 CDS28145.1 - 3.8e-05 23.4 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) PEHE PF15275.6 CDS28146.1 - 1e-13 52.1 5.8 1e-13 52.1 5.8 3.0 2 2 0 2 2 2 1 PEHE domain MFS_1 PF07690.16 CDS28148.2 - 1.2e-16 60.6 33.4 9e-13 47.9 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LYRIC PF15686.5 CDS28148.2 - 3.9 6.9 3.6 5.6 6.4 3.6 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family PetM PF08041.11 CDS28148.2 - 4.8 6.9 10.0 9.6 5.9 1.1 3.9 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 HTH_Tnp_Tc3_1 PF11427.8 CDS28150.1 - 0.064 13.1 4.3 0.9 9.4 0.2 3.4 3 1 0 3 3 3 0 Tc3 transposase Pup PF05639.11 CDS28150.1 - 0.09 13.7 0.0 0.25 12.3 0.0 1.7 1 0 0 1 1 1 0 Pup-like protein FERM_N PF09379.10 CDS28151.1 - 6.6e-09 35.6 0.7 1.1e-08 34.9 0.1 1.7 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.18 CDS28151.1 - 1.9e-05 25.1 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 2 1 FERM central domain KAsynt_C_assoc PF16197.5 CDS28153.2 - 1.2 9.6 5.1 0.97 9.9 1.8 2.3 1 1 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Synthase_beta PF11421.8 CDS28153.2 - 1.7 9.4 7.4 3.9 8.2 1.0 2.7 2 0 0 2 2 2 0 ATP synthase F1 beta subunit DEAD PF00270.29 CDS28154.1 - 2e-52 177.5 0.0 3.2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS28154.1 - 1.6e-31 108.9 0.0 9.9e-31 106.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS28154.1 - 7.9e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CDS28154.1 - 0.026 13.3 0.0 0.093 11.5 0.0 1.8 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Terminase_6 PF03237.15 CDS28154.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Terminase-like family AAA_22 PF13401.6 CDS28154.1 - 0.14 12.4 0.8 1.2 9.4 0.8 2.3 1 1 0 1 1 1 0 AAA domain DNA_photolyase PF00875.18 CDS28155.1 - 2.3e-18 66.8 0.0 6.3e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.14 CDS28155.1 - 0.0036 16.8 1.1 0.011 15.2 1.1 1.8 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase CHASE2 PF05226.11 CDS28155.1 - 0.044 13.5 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain P53 PF00870.18 CDS28156.1 - 7e-30 104.2 0.0 1.3e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 P53 DNA-binding domain Peptidase_C54 PF03416.19 CDS28157.1 - 6e-73 245.6 0.0 7.6e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_L20 PF00453.18 CDS28158.1 - 2.5e-23 82.2 0.7 3.1e-23 81.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 MAS20 PF02064.15 CDS28159.1 - 1.1e-18 67.6 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor MCLC PF05934.11 CDS28160.1 - 8.8e-05 21.4 0.2 0.0021 16.9 0.0 1.9 1 1 0 2 2 2 2 Mid-1-related chloride channel (MCLC) Q_salvage PF10343.9 CDS28161.1 - 1.2e-106 356.5 0.0 1.3e-106 356.3 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 CDS28161.1 - 0.00099 17.9 0.1 0.61 8.7 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF1688) WW PF00397.26 CDS28162.1 - 4.1e-07 30.0 4.3 4.1e-07 30.0 4.3 2.6 3 0 0 3 3 3 1 WW domain Lipoprotein_10 PF03202.13 CDS28162.1 - 0.42 11.0 7.2 0.38 11.2 0.3 2.4 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region PHC2_SAM_assoc PF16616.5 CDS28162.1 - 0.78 10.6 8.3 1.5 9.6 8.3 1.5 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RhoGEF PF00621.20 CDS28162.1 - 4.5 7.5 9.3 13 6.0 1.5 3.0 1 1 1 3 3 3 0 RhoGEF domain SNRNP27 PF08648.12 CDS28163.1 - 2.2e-29 101.3 5.3 4.2e-29 100.4 5.3 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins THRAP3_BCLAF1 PF15440.6 CDS28163.1 - 0.13 11.3 26.8 0.16 11.0 26.8 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Glutaredoxin PF00462.24 CDS28164.1 - 7.8e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 CDS28164.1 - 5.7e-06 26.3 0.0 6.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.14 CDS28164.1 - 0.00015 22.1 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 CDS28164.1 - 0.0029 17.3 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 CDS28164.1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CDS28164.1 - 0.096 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain MIP PF00230.20 CDS28165.1 - 1.7e-33 116.3 5.3 2e-33 116.0 5.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein AtpR PF12966.7 CDS28165.1 - 0.0019 18.6 2.8 0.0026 18.1 0.8 2.1 2 0 0 2 2 2 1 N-ATPase, AtpR subunit MIP PF00230.20 CDS28166.1 - 2.5e-38 132.0 5.6 3.1e-38 131.8 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Secretogranin_V PF05281.11 CDS28167.1 - 4.9e-21 75.4 1.5 9.2e-21 74.5 0.5 1.8 2 0 0 2 2 2 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) MFS_1 PF07690.16 CDS28168.1 - 2e-28 99.4 34.3 7.9e-21 74.4 10.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Gtr1_RagA PF04670.12 CDS28169.2 - 2.3e-88 295.5 0.0 2.7e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CDS28169.2 - 5.8e-05 22.6 0.0 8.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS28169.2 - 6.9e-05 23.1 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS28169.2 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.7 2 0 0 2 2 2 1 Ras family Metallopep PF12044.8 CDS28170.2 - 7.3e-49 166.5 0.0 8.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 CDS28170.2 - 0.023 14.9 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDS28170.2 - 0.031 14.8 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 CDS28170.2 - 0.055 13.4 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A WLM PF08325.10 CDS28170.2 - 0.087 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 WLM domain ITAM_Cys-rich PF10538.9 CDS28170.2 - 0.27 11.0 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif PCI PF01399.27 CDS28171.1 - 3.2e-19 69.4 0.1 9.7e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 CDS28171.1 - 0.13 12.5 0.5 7.2 7.0 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Myb_DNA-bind_7 PF15963.5 CDS28172.1 - 7.9e-24 83.4 3.2 1.4e-23 82.6 2.5 1.9 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CDS28172.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Afi1 PF07792.12 CDS28172.1 - 0.25 11.8 10.2 0.051 14.1 4.0 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PRAS PF15798.5 CDS28172.1 - 4.1 8.0 9.7 1 10.0 2.5 2.9 2 1 0 2 2 2 0 Proline-rich AKT1 substrate 1 BCAS2 PF05700.11 CDS28174.2 - 1.6e-66 223.9 6.8 2e-66 223.6 6.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 CDS28174.2 - 0.041 13.8 1.4 0.16 11.9 0.2 2.1 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor ACCA PF03255.14 CDS28174.2 - 0.044 13.6 1.4 0.073 12.9 1.4 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit EzrA PF06160.12 CDS28174.2 - 0.071 11.3 7.3 0.15 10.2 0.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Coiled-coil_56 PF09813.9 CDS28174.2 - 0.18 11.9 2.1 0.54 10.3 2.1 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF3970 PF13113.6 CDS28174.2 - 0.23 11.7 2.0 7.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) Helo_like_N PF17111.5 CDS28174.2 - 1.2 8.5 6.3 4.5 6.6 3.2 2.3 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins NAD-GH PF10712.9 CDS28176.1 - 1.7e-16 59.9 0.0 1.9e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase HDPD PF02924.14 CDS28176.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D NAD-GH PF10712.9 CDS28177.2 - 0.00013 20.6 5.6 0.00016 20.3 5.6 1.1 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase Spo7 PF03907.13 CDS28177.2 - 0.46 9.9 3.4 0.82 9.1 3.4 1.4 1 0 0 1 1 1 0 Spo7-like protein HSP70 PF00012.20 CDS28178.2 - 9.1e-261 866.3 9.2 1e-260 866.1 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDS28178.2 - 5e-18 65.0 1.5 2.1e-17 62.9 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 CDS28178.2 - 0.018 15.4 2.4 7.3 7.1 0.1 3.2 3 1 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 CDS28178.2 - 0.043 13.0 0.0 0.12 11.6 0.0 1.8 1 0 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.20 CDS28178.2 - 0.05 13.1 0.1 8.4 5.8 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 CDS28178.2 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP90 PF00183.18 CDS28179.1 - 3.2e-57 194.6 12.5 1.5e-48 166.0 8.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDS28179.1 - 1.9e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDS28179.1 - 7.7e-06 26.4 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 CDS28180.1 - 4.9e-56 190.7 0.1 1.8e-54 185.5 0.0 2.4 2 1 0 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 CDS28180.1 - 2e-07 31.5 0.1 3.7e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDS28180.1 - 3.5e-05 23.6 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP70 PF00012.20 CDS28181.2 - 5.9e-102 341.8 17.4 2.2e-71 240.8 0.3 2.0 1 1 1 2 2 2 2 Hsp70 protein Mago_nashi PF02792.14 CDS28181.2 - 0.13 12.4 2.8 0.36 10.9 0.0 2.4 2 1 1 3 3 3 0 Mago nashi protein HSP90 PF00183.18 CDS28182.1 - 1.5e-224 746.7 22.5 2e-224 746.3 22.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDS28182.1 - 5e-14 52.8 0.1 9.9e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDS28182.1 - 7.4e-10 38.8 0.1 7.4e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CDS28182.1 - 0.042 13.9 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Tumour suppressor protein MBOAT PF03062.19 CDS28183.1 - 3.1e-27 95.8 18.5 3.1e-27 95.8 18.5 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ashwin PF15323.6 CDS28183.1 - 0.0095 16.0 0.5 0.014 15.4 0.5 1.2 1 0 0 1 1 1 1 Developmental protein DUF1925 PF09094.11 CDS28183.1 - 5.7 7.3 7.7 0.17 12.2 0.8 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1925) Pkinase PF00069.25 CDS28184.1 - 4.2e-54 183.7 0.0 4.3e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PH_3 PF14593.6 CDS28184.1 - 3.4e-37 126.7 0.0 6.8e-37 125.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 CDS28184.1 - 1.1e-25 90.4 0.0 2.6e-25 89.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS28184.1 - 3.1e-05 23.4 0.0 0.073 12.4 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CDS28184.1 - 9.2e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 CDS28184.1 - 0.0013 19.2 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Kdo PF06293.14 CDS28184.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS28184.1 - 0.059 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 CDS28185.2 - 2e-46 158.5 0.0 3.2e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28185.2 - 6.1e-23 81.4 0.0 8.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS28185.2 - 0.00017 20.5 0.3 0.00037 19.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Selenoprotein_S PF06936.11 CDS28185.2 - 0.1 12.4 2.1 0.16 11.8 2.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Kinase-like PF14531.6 CDS28185.2 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CDS28185.2 - 0.16 11.9 0.0 4.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sulfate_transp PF00916.20 CDS28186.2 - 3.4e-93 312.4 19.2 4.8e-93 311.9 19.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDS28186.2 - 3.9e-23 81.3 0.0 8e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain zf-LITAF-like PF10601.9 CDS28186.2 - 1.7 9.0 9.5 1.3 9.4 2.3 2.9 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain UPF0506 PF11703.8 CDS28187.1 - 1.4e-21 76.6 20.0 1.8e-21 76.3 20.0 1.2 1 0 0 1 1 1 1 UPF0506 Dickkopf_N PF04706.12 CDS28187.1 - 0.0029 18.0 20.8 0.0075 16.7 16.0 2.2 1 1 1 2 2 2 2 Dickkopf N-terminal cysteine-rich region Conotoxin_I2 PF17557.2 CDS28187.1 - 2.5 8.3 20.3 0.35 11.0 8.5 2.5 2 1 0 2 2 2 0 I2-superfamily conotoxins Pkinase PF00069.25 CDS28188.1 - 6.6e-68 228.9 0.0 7.7e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28188.1 - 9.9e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS28188.1 - 0.00011 21.2 0.0 0.00033 19.7 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS28188.1 - 0.00026 20.4 0.0 0.38 10.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CDS28188.1 - 0.047 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec23_trunk PF04811.15 CDS28188.1 - 0.058 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Pkinase_fungal PF17667.1 CDS28188.1 - 0.065 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CDS28188.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EF_TS PF00889.19 CDS28188.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor TS RIIa PF02197.17 CDS28190.2 - 0.0063 16.2 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Tox-PLDMTX PF15645.6 CDS28190.2 - 0.053 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Sterol-sensing PF12349.8 CDS28191.1 - 2.2e-33 115.2 8.0 4.1e-33 114.4 8.0 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Ribosomal_L1 PF00687.21 CDS28191.1 - 3.1e-29 102.2 0.1 6e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Patched PF02460.18 CDS28191.1 - 1.5e-12 46.4 4.6 4.6e-11 41.6 4.6 2.1 2 0 0 2 2 2 2 Patched family WD40 PF00400.32 CDS28191.1 - 0.058 14.3 0.0 0.51 11.3 0.0 2.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Acetyltransf_1 PF00583.25 CDS28192.1 - 3.4e-05 24.1 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDS28192.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CDS28192.1 - 0.012 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CDS28192.1 - 0.032 14.4 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS28192.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5506 PF17611.2 CDS28192.1 - 0.15 11.9 0.5 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5506) Acetyltransf_CG PF14542.6 CDS28192.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TPR_1 PF00515.28 CDS28193.1 - 3.5e-14 51.9 0.7 0.00012 21.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS28193.1 - 2.6e-11 42.7 5.2 2.4e-05 24.1 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat FKBP_C PF00254.28 CDS28193.1 - 7.1e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.6 CDS28193.1 - 3e-06 26.8 0.1 0.059 13.1 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDS28193.1 - 4e-06 26.6 0.2 0.0042 17.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS28193.1 - 3.1e-05 24.4 0.4 0.005 17.5 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28193.1 - 0.00033 20.8 0.1 0.0031 17.8 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28193.1 - 0.00051 20.3 0.2 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CDS28193.1 - 0.00087 19.3 0.7 0.56 10.3 0.0 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 CDS28193.1 - 0.001 19.2 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28193.1 - 0.0028 17.6 0.3 0.21 11.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28193.1 - 0.011 16.2 0.0 0.041 14.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS28193.1 - 0.014 16.0 0.1 0.05 14.3 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HA2 PF04408.23 CDS28194.1 - 1.7e-21 76.5 0.0 4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 CDS28194.1 - 0.00014 21.7 0.1 0.00026 20.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_3 PF13606.6 CDS28194.1 - 0.0062 16.9 0.0 0.21 12.3 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat OB_NTP_bind PF07717.16 CDS28194.1 - 0.0099 16.2 0.0 0.032 14.6 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 CDS28194.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDS28194.1 - 0.014 16.0 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 CDS28194.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 CDS28194.1 - 0.02 14.7 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank PF00023.30 CDS28194.1 - 0.026 15.0 0.0 0.12 12.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat AAA_23 PF13476.6 CDS28194.1 - 0.042 14.4 0.6 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDS28194.1 - 0.098 12.6 0.1 0.34 10.8 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CDS28194.1 - 0.12 12.7 0.1 0.57 10.6 0.0 2.3 2 1 0 2 2 1 0 AAA ATPase domain AAA PF00004.29 CDS28195.1 - 2.6e-55 186.5 0.0 2e-41 141.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDS28195.1 - 3.4e-08 33.4 0.0 0.0015 18.3 0.0 3.4 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDS28195.1 - 1.2e-07 31.8 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 CDS28195.1 - 3.7e-07 30.7 0.5 0.0089 16.4 0.2 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 CDS28195.1 - 2.9e-06 27.0 0.1 0.00018 21.2 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain TsaE PF02367.17 CDS28195.1 - 1.1e-05 25.5 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CDS28195.1 - 1.6e-05 24.9 0.0 0.0026 17.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDS28195.1 - 1.9e-05 25.2 0.1 0.02 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDS28195.1 - 4.1e-05 23.8 0.0 0.00075 19.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDS28195.1 - 7.5e-05 23.0 0.6 0.1 12.9 0.1 3.6 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 CDS28195.1 - 9.7e-05 22.4 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDS28195.1 - 0.00015 22.1 0.0 0.3 11.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_3 PF07726.11 CDS28195.1 - 0.00063 19.6 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDS28195.1 - 0.00068 19.8 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDS28195.1 - 0.00081 18.8 1.9 0.025 14.0 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CDS28195.1 - 0.001 19.4 0.6 0.73 10.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 CDS28195.1 - 0.0013 18.7 0.5 0.6 10.0 0.1 3.4 2 2 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 CDS28195.1 - 0.0017 18.1 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 CDS28195.1 - 0.0025 18.1 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDS28195.1 - 0.0052 16.0 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_11 PF13086.6 CDS28195.1 - 0.0071 16.2 0.3 2.2 8.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CDS28195.1 - 0.0099 15.6 0.0 0.073 12.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CDS28195.1 - 0.03 14.4 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CDS28195.1 - 0.046 13.6 0.5 17 5.3 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.6 CDS28195.1 - 0.05 14.0 1.6 1.2 9.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CDS28195.1 - 0.064 12.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDS28195.1 - 0.087 12.5 0.2 7.4 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDS28195.1 - 0.1 12.3 0.0 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 CDS28195.1 - 0.12 12.5 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family ATPase_2 PF01637.18 CDS28195.1 - 0.12 12.2 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 CDS28195.1 - 0.13 11.6 0.0 15 4.9 0.0 2.8 3 1 0 3 3 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 CDS28195.1 - 0.13 11.5 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CDS28195.1 - 0.14 12.7 0.1 7.4 7.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 CDS28195.1 - 0.14 11.7 0.2 4.5 6.8 0.1 2.8 2 1 1 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CDS28195.1 - 0.69 9.6 3.0 5 6.8 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase WD40 PF00400.32 CDS28198.1 - 1.4e-07 32.1 22.6 4.2 8.4 0.0 10.9 11 0 0 11 11 11 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28198.1 - 4.9e-06 26.8 0.0 1.3 9.4 0.0 5.1 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CDS28198.1 - 0.00023 21.6 1.9 0.47 11.0 0.0 5.3 5 0 0 5 5 5 1 PQQ-like domain PQQ PF01011.21 CDS28198.1 - 0.019 14.9 0.2 18 5.5 0.0 4.3 4 0 0 4 4 4 0 PQQ enzyme repeat BBS2_Mid PF14783.6 CDS28198.1 - 0.15 12.1 0.0 23 5.1 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region GATA PF00320.27 CDS28199.1 - 3.7e-29 100.0 17.0 3.1e-15 55.5 4.9 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CDS28199.1 - 1.6e-05 24.3 7.3 0.011 15.2 0.6 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 CDS28199.1 - 0.025 14.5 7.5 1.8 8.5 1.3 3.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C4pol PF14260.6 CDS28199.1 - 0.049 14.1 3.4 0.19 12.2 2.5 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Zn-ribbon_8 PF09723.10 CDS28199.1 - 0.062 13.4 3.3 7.2 6.8 0.5 2.9 2 2 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 CDS28199.1 - 0.074 13.1 6.8 3.6 7.7 7.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.12 CDS28199.1 - 0.079 13.1 6.4 0.55 10.4 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CDS28199.1 - 0.24 11.3 2.9 14 5.6 1.1 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 CDS28199.1 - 0.29 10.5 5.5 0.28 10.6 0.5 3.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_Tnp_IS1595 PF12760.7 CDS28199.1 - 0.92 9.5 8.5 4 7.5 0.5 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrom_c3_2 PF14537.6 CDS28199.1 - 1.2 9.6 5.1 0.25 11.8 0.9 2.1 2 0 0 2 2 2 0 Cytochrome c3 Prim_Zn_Ribbon PF08273.12 CDS28199.1 - 5.3 7.4 9.7 3.6 7.9 1.8 3.3 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 CDS28199.1 - 5.9 6.7 9.4 2.4 8.0 0.8 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain EGF PF00008.27 CDS28200.1 - 2.6e-05 24.4 26.1 0.03 14.6 6.0 5.0 4 0 0 4 4 4 4 EGF-like domain GYF PF02213.16 CDS28201.2 - 5.7e-14 51.5 0.1 1.4e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDS28201.2 - 0.058 13.2 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 GYF domain 2 DUF2951 PF11166.8 CDS28201.2 - 0.98 9.7 2.2 1.5 9.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF1041 PF06292.17 CDS28203.1 - 5.1e-30 104.0 0.9 5.1e-30 104.0 0.9 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) PH PF00169.29 CDS28203.1 - 6.8e-07 29.8 0.0 1.7e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Tctex-1 PF03645.13 CDS28203.1 - 0.084 13.1 0.2 0.33 11.2 0.2 2.0 1 0 0 1 1 1 0 Tctex-1 family PRP38 PF03371.15 CDS28204.1 - 9.1e-56 188.5 0.0 1.2e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Presenilin PF01080.17 CDS28204.1 - 5.4 5.7 6.8 8 5.1 6.8 1.3 1 0 0 1 1 1 0 Presenilin Vel1p PF10339.9 CDS28207.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive DUF3396 PF11876.8 CDS28207.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) Deltameth_res PF16020.5 CDS28210.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Deltamethrin resistance Peptidase_C10 PF01640.17 CDS28210.1 - 0.13 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase C10 family Exo_endo_phos_2 PF14529.6 CDS28211.1 - 1.7e-12 47.2 1.4 4.6e-12 45.8 0.2 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase NUDIX PF00293.28 CDS28211.1 - 1.7e-07 31.3 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Exo_endo_phos PF03372.23 CDS28211.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Acyltransferase PF01553.21 CDS28212.1 - 1.2e-28 99.5 0.0 1.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Bap31_Bap29_C PF18035.1 CDS28213.1 - 0.033 14.2 0.6 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RRM_1 PF00076.22 CDS28216.1 - 9e-12 44.6 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS28216.1 - 8.8e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_2 PF03567.14 CDS28217.1 - 3.8e-09 36.8 0.6 8e-09 35.8 0.3 1.5 1 1 0 2 2 2 1 Sulfotransferase family DUF272 PF03312.15 CDS28217.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF272) FAR1 PF03101.15 CDS28220.1 - 3.5e-07 30.8 2.1 7.6e-07 29.7 0.4 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain Ferritin PF00210.24 CDS28221.2 - 2.2e-34 118.4 3.0 2.5e-34 118.2 3.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 CDS28221.2 - 0.0061 17.0 2.3 0.0086 16.5 2.3 1.4 1 1 0 1 1 1 1 Rubrerythrin Mad3_BUB1_I PF08311.12 CDS28224.2 - 9.4e-17 61.2 0.2 2.2e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Band_7 PF01145.25 CDS28225.1 - 2.6e-34 118.8 2.6 3.7e-34 118.3 2.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDS28225.1 - 0.00035 20.4 0.2 0.00075 19.3 0.2 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 CDS28225.1 - 0.1 13.0 0.2 0.34 11.3 0.2 1.9 1 0 0 1 1 1 0 Phage protein Gp68 BAH PF01426.18 CDS28226.1 - 8.6e-26 90.2 0.1 2.5e-25 88.7 0.1 1.8 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.24 CDS28226.1 - 4.3e-08 33.8 0.0 1.7e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain zf-C2H2 PF00096.26 CDS28226.1 - 0.00068 20.0 2.6 0.0034 17.8 0.4 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type MTA_R1 PF17226.2 CDS28226.1 - 0.00086 19.4 0.7 0.0025 17.9 0.7 1.7 1 0 0 1 1 1 1 MTA R1 domain DBINO PF13892.6 CDS28226.1 - 0.0045 17.3 2.3 0.93 9.8 0.1 2.5 2 0 0 2 2 2 2 DNA-binding domain GATA PF00320.27 CDS28226.1 - 0.01 15.4 9.5 0.026 14.1 9.5 1.7 1 0 0 1 1 1 0 GATA zinc finger FOXP-CC PF16159.5 CDS28226.1 - 0.084 13.5 0.1 0.24 12.1 0.1 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDS28226.1 - 0.1 13.5 0.3 0.1 13.5 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FHA PF00498.26 CDS28227.1 - 1.2e-10 41.6 0.1 2.2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDS28227.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Ank_2 PF12796.7 CDS28228.1 - 4.1e-34 117.0 4.4 5.4e-12 46.1 0.7 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS28228.1 - 1.1e-27 95.7 5.8 4.1e-05 23.8 0.4 6.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS28228.1 - 3.2e-27 94.5 4.4 1.8e-07 31.5 0.1 4.9 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS28228.1 - 6.2e-24 83.3 9.2 0.0007 19.9 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 CDS28228.1 - 6.8e-23 78.3 4.9 0.0002 21.5 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat DUF951 PF06107.11 CDS28228.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Taeniidae_ag PF05596.11 CDS28229.1 - 2e-18 66.1 0.4 2.4e-18 65.9 0.4 1.1 1 0 0 1 1 1 1 Taeniidae antigen Mito_fiss_reg PF05308.11 CDS28232.1 - 0.2 11.7 2.5 0.3 11.1 2.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Exo_endo_phos PF03372.23 CDS28239.1 - 7.2e-15 55.1 0.0 1.6e-14 54.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CDS28239.1 - 0.0021 18.1 3.3 0.0052 16.8 3.3 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CDS28239.1 - 0.014 15.3 0.1 0.056 13.3 0.1 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase XRCC1_N PF01834.16 CDS28240.1 - 3.3e-54 182.9 0.8 6.3e-54 182.0 0.8 1.5 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT_2 PF16589.5 CDS28240.1 - 2e-21 76.2 0.1 7.7e-14 51.9 0.1 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDS28240.1 - 2.3e-14 53.5 1.3 2.3e-08 34.3 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDS28240.1 - 4.7e-13 48.9 0.0 2.1e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain LIG3_BRCT PF16759.5 CDS28240.1 - 0.0036 17.6 0.2 0.066 13.5 0.0 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain YL1 PF05764.13 CDS28240.1 - 1.2 9.3 14.1 2.4 8.2 14.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 CDS28241.1 - 3.6e-68 229.8 0.0 4.9e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28241.1 - 4.7e-33 114.6 0.0 7.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS28241.1 - 1.4e-06 27.5 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS28241.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS28241.1 - 0.00036 20.5 0.3 0.0033 17.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS28241.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDS28241.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDS28241.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CENP-H PF05837.12 CDS28242.1 - 2.5 8.6 7.1 1.1 9.7 3.9 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3591 PF12157.8 CDS28243.1 - 3.5e-143 477.5 0.0 2.4e-142 474.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CDS28243.1 - 4.2e-39 132.5 7.3 6.6e-20 71.0 1.0 2.6 2 0 0 2 2 2 2 Bromodomain zf-CCHC_6 PF15288.6 CDS28243.1 - 8.9e-08 31.8 1.9 2.2e-07 30.6 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle TBP-binding PF09247.11 CDS28243.1 - 0.0096 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 TATA box-binding protein binding NuA4 PF09340.10 CDS28244.1 - 6.2e-24 83.7 0.0 1.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RRM_1 PF00076.22 CDS28245.1 - 2.3e-05 24.1 0.0 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnl2_NKP2 PF09447.10 CDS28245.1 - 0.087 13.0 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein RRM_5 PF13893.6 CDS28245.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb4 PF03874.16 CDS28246.1 - 8.2e-17 61.7 0.9 2.8e-16 60.0 0.9 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 RT_RNaseH PF17917.1 CDS28247.1 - 3.5e-24 85.1 0.1 6.7e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS28247.1 - 5.4e-20 71.3 0.1 1.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS28247.1 - 4e-05 23.8 0.4 0.16 12.2 0.0 2.9 2 1 1 3 3 3 2 Integrase core domain RVT_1 PF00078.27 CDS28247.1 - 0.0022 17.6 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 CDS28247.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pao retrotransposon peptidase Pkinase PF00069.25 CDS28248.1 - 2.7e-60 204.0 0.0 7.8e-60 202.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28248.1 - 2.7e-27 95.7 0.0 4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS28248.1 - 0.00088 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDS28248.1 - 0.0021 18.0 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS28248.1 - 0.11 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 CDS28249.2 - 1.6e-11 44.0 0.0 3.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CDS28249.2 - 4.9e-11 43.3 0.0 7e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin CPSF73-100_C PF11718.8 CDS28250.1 - 2.6e-38 131.8 0.3 6.9e-37 127.1 0.3 2.2 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CDS28250.1 - 9.4e-33 112.8 0.0 1.8e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CDS28250.1 - 5.9e-25 87.8 0.1 4.1e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CDS28250.1 - 6.9e-20 70.7 0.0 1.6e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CDS28250.1 - 6.8e-18 65.4 0.0 1.1e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CDS28250.1 - 2.5e-09 37.2 0.1 8e-09 35.6 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CDS28250.1 - 3.1e-08 33.4 0.2 3.3e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CDS28250.1 - 0.02 14.1 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family Tetraspanin PF00335.20 CDS28252.1 - 1.8e-21 76.9 20.9 1.3e-12 47.9 2.6 2.0 1 1 1 2 2 2 2 Tetraspanin family DUF2569 PF10754.9 CDS28252.1 - 0.27 11.7 5.7 0.23 11.9 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) MARVEL PF01284.23 CDS28252.1 - 0.65 10.0 9.7 0.072 13.1 4.4 1.9 2 0 0 2 2 2 0 Membrane-associating domain PrgI PF12666.7 CDS28252.1 - 2.9 8.7 6.3 0.59 10.9 1.7 1.9 2 0 0 2 2 2 0 PrgI family protein Spec3 PF15795.5 CDS28252.1 - 3.3 8.3 9.7 1 10.0 5.7 2.1 2 0 0 2 2 2 0 Ectodermal ciliogenesis protein DUF2976 PF11190.8 CDS28252.1 - 5.9 6.8 8.6 0.68 9.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) Tetraspanin PF00335.20 CDS28253.1 - 8.6e-11 42.0 0.6 8.6e-11 42.0 0.6 1.5 1 1 0 2 2 2 1 Tetraspanin family CD20 PF04103.15 CDS28253.1 - 5.1e-06 26.7 1.4 1.2e-05 25.5 1.6 1.7 1 1 0 1 1 1 1 CD20-like family Wzy_C PF04932.15 CDS28253.1 - 0.0046 16.6 0.4 0.0061 16.2 0.4 1.3 1 0 0 1 1 1 1 O-Antigen ligase DUF2079 PF09852.9 CDS28253.1 - 0.025 13.5 0.1 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) YtpI PF14007.6 CDS28253.1 - 0.042 14.0 0.9 0.11 12.7 0.9 1.8 1 1 0 1 1 1 0 YtpI-like protein DUF308 PF03729.13 CDS28253.1 - 0.043 14.1 8.2 0.043 14.1 8.2 2.2 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2981 PF11200.8 CDS28253.1 - 0.079 12.7 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) NKAIN PF05640.14 CDS28253.1 - 1 8.5 6.0 1 8.6 4.3 1.9 1 1 0 1 1 1 0 Na,K-Atpase Interacting protein DUF5113 PF17140.4 CDS28254.1 - 0.048 13.5 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Acetyltransf_1 PF00583.25 CDS28255.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS28255.1 - 3e-09 37.2 0.1 4.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS28255.1 - 5.8e-09 36.0 0.1 7.6e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDS28255.1 - 1.8e-05 24.6 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CDS28255.1 - 4.8e-05 23.5 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CDS28255.1 - 6.4e-05 22.7 0.0 9.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDS28255.1 - 0.00013 22.1 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF762 PF05555.11 CDS28255.1 - 0.0043 16.7 0.1 0.0053 16.4 0.1 1.2 1 0 0 1 1 1 1 Coxiella burnetii protein of unknown function (DUF762) PanZ PF12568.8 CDS28255.1 - 0.0061 16.3 0.0 0.0095 15.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 CDS28255.1 - 0.013 16.2 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB_2 PF02214.22 CDS28257.2 - 2.3e-28 98.4 1.0 4.7e-28 97.4 0.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.31 CDS28257.2 - 2.8e-25 89.0 12.5 2.8e-25 89.0 12.5 1.6 1 1 1 2 2 2 1 Ion transport protein BTB_3 PF16017.5 CDS28257.2 - 0.00039 20.5 0.1 0.0013 18.8 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 CDS28257.2 - 0.013 14.2 5.8 0.023 13.4 5.8 1.4 1 0 0 1 1 1 0 Polycystin cation channel Shal-type PF11601.8 CDS28257.2 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal CoiA PF06054.11 CDS28257.2 - 0.099 11.8 0.1 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Competence protein CoiA-like family Ion_trans_2 PF07885.16 CDS28257.2 - 0.21 11.6 7.8 0.051 13.6 2.8 2.5 2 0 0 2 2 2 0 Ion channel DUF4140 PF13600.6 CDS28258.1 - 0.024 15.1 3.2 0.024 15.1 3.2 5.6 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Integrin_alpha2 PF08441.12 CDS28259.1 - 3.5e-28 98.7 0.0 6.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CDS28259.1 - 3.3e-15 55.9 2.2 2.4e-06 27.5 0.0 3.9 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.6 CDS28259.1 - 2.6e-09 37.6 1.5 0.019 15.6 0.0 3.9 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.20 CDS28259.1 - 0.0071 16.2 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region RNA_pol_Rpc34 PF05158.12 CDS28261.1 - 8.3e-40 137.2 0.8 1.5e-39 136.4 0.8 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.19 CDS28261.1 - 0.0084 16.0 0.2 0.034 14.0 0.1 2.1 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB ATP-cone PF03477.16 CDS28261.1 - 0.082 13.5 0.5 0.61 10.7 0.0 2.5 2 1 0 2 2 2 0 ATP cone domain DUF4388 PF14332.6 CDS28261.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) ribosomal_L24 PF17136.4 CDS28262.1 - 2e-07 31.3 0.0 3.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CDS28262.1 - 0.00023 21.0 1.2 0.00023 21.0 1.2 1.8 2 0 0 2 2 2 1 KOW motif EF-hand_8 PF13833.6 CDS28263.1 - 1.6e-17 63.1 5.2 1.2e-09 37.9 0.0 4.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 CDS28263.1 - 1.6e-17 61.6 2.1 4.4e-06 25.9 0.2 5.5 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 CDS28263.1 - 3.2e-16 57.8 4.0 1e-06 28.1 0.2 5.5 5 1 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 CDS28263.1 - 1.6e-15 57.3 1.8 1.5e-05 25.3 0.1 4.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS28263.1 - 1.9e-11 42.9 6.8 3.9e-05 23.0 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CDS28263.1 - 9.6e-07 28.7 0.1 0.08 12.9 0.0 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDS28263.1 - 0.01 16.2 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain HA2 PF04408.23 CDS28264.1 - 2.5e-21 76.0 0.0 2.5e-21 76.0 0.0 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDS28264.1 - 7.1e-19 68.0 0.0 1.7e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDS28264.1 - 4.1e-12 46.4 0.0 9.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS28264.1 - 2.4e-05 24.2 0.1 7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDS28264.1 - 0.00088 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS28264.1 - 0.0032 17.8 0.2 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDS28264.1 - 0.005 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDS28264.1 - 0.0052 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein VbhA PF18495.1 CDS28264.1 - 0.0054 16.6 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 Antitoxin VbhA DUF2075 PF09848.9 CDS28264.1 - 0.046 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 CDS28264.1 - 0.051 13.6 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain Reprolysin PF01421.19 CDS28264.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease AAA_16 PF13191.6 CDS28264.1 - 0.099 13.0 0.0 0.41 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CDS28264.1 - 1.8 9.1 0.0 1.8 9.1 0.0 3.0 2 1 0 2 2 1 0 AAA domain Complex1_LYR PF05347.15 CDS28265.1 - 1e-10 41.5 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDS28265.1 - 1.1e-05 26.1 0.2 1.1e-05 26.1 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3342 PF11822.8 CDS28265.1 - 0.11 12.7 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) WD40 PF00400.32 CDS28266.1 - 2.6e-10 40.7 4.4 0.71 10.8 0.0 6.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28266.1 - 0.0036 17.6 0.0 6.8 7.1 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Fe-S_biosyn PF01521.20 CDS28267.1 - 1.4e-13 51.0 0.2 2.7e-13 50.1 0.2 1.4 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Metallophos PF00149.28 CDS28269.1 - 2e-23 83.9 0.0 3.2e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 CDS28269.1 - 1.8e-10 39.6 2.1 0.048 13.2 0.5 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDS28269.1 - 1.1e-08 34.3 1.0 0.0036 17.1 0.2 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CDS28269.1 - 7.2e-07 29.6 1.3 8.8e-06 26.1 2.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS28269.1 - 0.0016 18.3 2.6 0.44 10.4 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair IQ PF00612.27 CDS28269.1 - 0.0055 16.4 0.6 0.019 14.8 0.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_5 PF13202.6 CDS28269.1 - 0.067 12.7 3.8 0.81 9.3 0.3 2.6 2 0 0 2 2 2 0 EF hand AcetylCoA_hydro PF02550.15 CDS28269.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain EF-hand_4 PF12763.7 CDS28269.1 - 0.17 11.9 0.5 0.68 9.9 0.5 2.0 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand wnt PF00110.19 CDS28270.2 - 1.9e-111 372.6 11.4 2.5e-111 372.2 11.4 1.1 1 0 0 1 1 1 1 wnt family V-set PF07686.17 CDS28271.2 - 3.5e-06 27.1 0.2 0.051 13.8 0.1 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.6 CDS28271.2 - 0.00025 21.6 0.2 0.45 11.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CDS28271.2 - 0.001 19.1 0.2 1.6 8.9 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.25 CDS28271.2 - 0.01 16.0 0.1 4 7.7 0.0 3.1 2 1 0 2 2 2 0 Immunoglobulin domain Ion_trans PF00520.31 CDS28272.2 - 3.1e-17 62.6 28.2 5.1e-17 61.9 28.1 1.4 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDS28272.2 - 2.4e-14 53.4 0.0 6.9e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDS28272.2 - 3.1e-14 52.7 10.5 3.1e-14 52.7 10.5 2.1 3 0 0 3 3 3 1 Ion channel Lig_chan PF00060.26 CDS28272.2 - 4.7 7.0 6.5 0.4 10.5 1.2 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Arf PF00025.21 CDS28273.1 - 2.2e-29 102.2 0.0 2.4e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDS28273.1 - 5.8e-09 35.8 0.0 6.4e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS28273.1 - 7.1e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDS28273.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.10 CDS28273.1 - 0.12 11.7 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDS28273.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2863 PF11062.8 CDS28274.2 - 0.034 12.5 0.0 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Toxin_19 PF08088.12 CDS28275.1 - 0.07 13.3 3.0 0.11 12.7 3.0 1.3 1 0 0 1 1 1 0 Conotoxin I-superfamily Homeodomain PF00046.29 CDS28276.1 - 7.8e-21 73.7 0.9 1.5e-20 72.8 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDS28276.1 - 0.74 9.3 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez SMN PF06003.12 CDS28276.1 - 0.92 8.7 18.9 0.19 11.0 3.1 2.8 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) Pex14_N PF04695.13 CDS28276.1 - 1.6 9.4 19.3 0.34 11.5 2.8 3.4 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transferrin PF00405.17 CDS28277.1 - 4.1e-102 341.7 0.0 5.5e-71 239.4 0.0 2.0 2 0 0 2 2 2 2 Transferrin DUF3421 PF11901.8 CDS28277.1 - 0.054 13.5 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) SPA PF08616.10 CDS28278.1 - 6.1e-10 39.1 0.1 3.8e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.21 CDS28278.1 - 0.0012 18.9 0.4 0.46 10.4 0.1 3.1 3 0 0 3 3 3 2 DENN (AEX-3) domain ASXH PF13919.6 CDS28278.1 - 0.028 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain Avl9 PF09794.9 CDS28278.1 - 0.14 10.8 0.1 0.21 10.2 0.1 1.2 1 0 0 1 1 1 0 Transport protein Avl9 Pan3_PK PF18101.1 CDS28279.2 - 3.7e-45 153.3 0.3 7.6e-45 152.3 0.3 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain DHR-2 PF06920.13 CDS28280.1 - 8.1e-113 377.8 1.1 1.5e-112 377.0 0.2 1.8 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 CDS28280.1 - 4.9e-26 91.8 0.0 1.1e-25 90.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins zf-C2H2_12 PF18658.1 CDS28282.1 - 7.5e-09 35.0 1.8 1.7e-08 33.9 1.1 1.9 2 0 0 2 2 2 1 Zinc-finger C2H2-type Pribosyltran_N PF13793.6 CDS28283.1 - 1.6e-44 150.5 1.2 9.9e-44 148.0 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDS28283.1 - 4.6e-43 147.4 0.5 5e-37 127.7 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDS28283.1 - 2.7e-17 62.8 1.5 1.3e-16 60.5 0.2 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDS28283.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_15 PF00723.21 CDS28284.1 - 4.7e-131 437.6 0.0 5.9e-131 437.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Sec7 PF01369.20 CDS28285.1 - 7.4e-28 97.5 0.1 1e-27 97.0 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 CDS28285.1 - 3e-06 27.0 0.9 8.1e-06 25.6 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDS28285.1 - 0.0077 16.1 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain DNA_pol_A_exo1 PF01612.20 CDS28287.1 - 3.2e-41 141.0 0.1 5.2e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CDS28287.1 - 1.7e-11 44.0 0.0 3.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 CDS28287.1 - 3.2e-11 43.8 0.1 1.2e-10 41.9 0.1 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain CASP_C PF08172.12 CDS28288.1 - 8.9e-53 179.2 10.8 8.9e-53 179.2 10.8 5.2 1 1 2 4 4 4 1 CASP C terminal Carb_anhydrase PF00194.21 CDS28291.1 - 7.5e-60 202.6 0.0 8.9e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 CDS28292.1 - 4.7e-08 33.5 0.1 0.00044 20.8 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS28292.1 - 1e-05 26.0 0.1 0.00014 22.4 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS28292.1 - 1.9e-05 24.8 0.1 0.031 14.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28292.1 - 0.00012 22.3 0.3 1.1 10.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.16 CDS28292.1 - 0.0002 21.6 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank PF00023.30 CDS28292.1 - 0.0012 19.2 0.8 0.62 10.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Aldedh PF00171.22 CDS28293.1 - 1.3e-07 30.5 0.8 0.0014 17.2 0.0 3.3 2 1 1 3 3 3 3 Aldehyde dehydrogenase family baeRF_family3 PF18845.1 CDS28293.1 - 0.24 11.6 0.0 0.62 10.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 DHFR_1 PF00186.19 CDS28294.1 - 5.5e-37 126.9 0.0 6.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Arm PF00514.23 CDS28297.1 - 0.02 14.9 0.1 8.2 6.6 0.0 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CorA PF01544.18 CDS28297.1 - 0.13 11.5 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0240 PF06784.11 CDS28298.1 - 5.3e-19 68.9 0.4 9.1e-19 68.2 0.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) RF-1 PF00472.20 CDS28299.1 - 2e-36 124.5 1.0 4e-36 123.5 1.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 CDS28299.1 - 1.9e-35 122.5 0.1 1.6e-34 119.5 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Utp11 PF03998.13 CDS28299.1 - 0.0014 18.7 0.4 0.0025 17.8 0.4 1.4 1 0 0 1 1 1 1 Utp11 protein dCMP_cyt_deam_1 PF00383.23 CDS28300.1 - 7.3e-14 51.5 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDS28300.1 - 2.3e-08 34.3 0.1 4.7e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CDS28300.1 - 0.1 12.2 1.1 0.21 11.2 0.1 1.9 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Med27 PF11571.8 CDS28300.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 27 Rpr2 PF04032.16 CDS28301.2 - 0.0003 21.0 2.8 18 5.7 0.0 5.2 4 0 0 4 4 4 3 RNAse P Rpr2/Rpp21/SNM1 subunit domain Trm112p PF03966.16 CDS28301.2 - 0.046 14.3 0.1 31 5.3 0.0 3.2 2 0 0 2 2 2 0 Trm112p-like protein potato_inhibit PF00280.18 CDS28302.2 - 1.3e-05 25.8 8.5 1.2e+02 3.5 0.0 8.2 7 0 0 7 7 7 0 Potato inhibitor I family SH3_10 PF17902.1 CDS28302.2 - 0.00099 19.1 0.1 3.3 7.8 0.0 4.3 5 0 0 5 5 5 2 SH3 domain Uroplakin_II PF07353.12 CDS28302.2 - 0.0015 18.1 0.0 24 4.3 0.0 3.7 3 0 0 3 3 3 3 Uroplakin II Plectin PF00681.20 CDS28302.2 - 0.017 15.0 0.0 3.2 7.7 0.0 3.6 2 0 0 2 2 2 0 Plectin repeat PIP49_C PF12260.8 CDS28302.2 - 0.15 11.6 0.2 0.41 10.3 0.2 1.7 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RsbRD_N PF14361.6 CDS28302.2 - 1.4 9.6 7.1 1.8e+02 2.9 0.1 4.9 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Cm_res_leader PF08077.11 CDS28302.2 - 9.2 6.8 6.9 2.5e+02 2.4 0.1 4.4 4 0 0 4 4 4 0 Chloramphenicol resistance gene leader peptide Acyltransferase PF01553.21 CDS28303.1 - 9.8e-18 64.1 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase bZIP_2 PF07716.15 CDS28304.1 - 1.5e-11 44.2 4.0 2.3e-11 43.6 4.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS28304.1 - 0.05 13.7 4.8 0.088 12.9 4.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor zf-U1 PF06220.12 CDS28305.1 - 1.4e-10 40.8 0.5 2.5e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 CDS28305.1 - 2.2e-09 37.2 6.4 4.2e-09 36.3 6.4 1.4 1 0 0 1 1 1 1 WW domain THF_DHG_CYH_C PF02882.19 CDS28306.1 - 7.8e-47 158.6 0.0 1.4e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CDS28306.1 - 8.3e-25 87.3 0.1 1.2e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF1856 PF08983.10 CDS28306.1 - 0.026 14.7 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Alg6_Alg8 PF03155.15 CDS28307.1 - 7.7e-144 480.3 32.7 9e-144 480.0 32.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ubiquitin PF00240.23 CDS28308.1 - 1.4e-15 56.8 2.6 5.2e-07 29.3 0.1 2.5 3 0 0 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.6 CDS28308.1 - 8.6e-08 32.5 0.4 0.0006 20.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 CDS28308.1 - 1.4e-07 31.2 1.9 0.00084 19.1 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDS28308.1 - 0.0011 18.9 0.4 0.76 9.9 0.0 3.4 3 1 0 3 3 3 1 Ubiquitin-like domain Cobl PF09469.10 CDS28308.1 - 0.077 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain ubiquitin PF00240.23 CDS28309.1 - 2.8e-19 68.6 0.0 3.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDS28309.1 - 2.5e-08 33.6 0.0 0.0073 16.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDS28309.1 - 0.057 13.9 0.1 0.64 10.5 0.0 2.6 2 2 0 2 2 2 0 Ubiquitin-like domain PhnJ PF06007.11 CDS28309.1 - 0.074 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ubiquitin_4 PF18036.1 CDS28309.1 - 0.099 12.7 0.2 34 4.6 0.0 3.2 2 1 1 3 3 3 0 Ubiquitin-like domain Astacin PF01400.24 CDS28310.2 - 5.9e-42 143.5 0.0 1.1e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) ShK PF01549.24 CDS28310.2 - 2e-25 89.0 84.8 3e-08 34.1 8.7 6.4 6 0 0 6 6 6 4 ShK domain-like Peptidase_M66 PF10462.9 CDS28310.2 - 0.0062 15.5 0.2 0.011 14.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 CDS28310.2 - 0.011 15.5 1.2 0.076 12.9 1.2 2.0 1 1 1 2 2 2 0 Matrixin MRP-S24 PF14955.6 CDS28311.1 - 3.5e-49 166.3 0.1 3.8e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 LssY_C PF14067.6 CDS28311.1 - 0.021 14.4 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus EF-hand_6 PF13405.6 CDS28312.1 - 3.4e-08 32.8 0.6 2.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS28312.1 - 2.1e-05 23.7 1.0 5.8e-05 22.4 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CDS28312.1 - 2.3e-05 24.8 0.4 0.00055 20.3 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS28312.1 - 2.9e-05 23.8 0.3 0.0062 16.4 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair UPF0154 PF03672.13 CDS28312.1 - 0.0015 18.6 0.0 0.2 11.7 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 CDS28312.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 CDS28312.1 - 0.17 12.2 0.0 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain PigN PF04987.14 CDS28313.1 - 5.7e-92 309.0 37.6 6.9e-92 308.7 37.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CDS28313.1 - 9.3e-14 51.8 2.0 5.2e-12 46.0 2.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CDS28313.1 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDS28313.1 - 1.2e-05 24.9 0.0 3.9e-05 23.2 0.0 1.7 1 1 0 2 2 2 1 Sulfatase EIAV_GP90 PF00971.18 CDS28313.1 - 0.16 10.6 0.1 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 NADH_dh_m_C1 PF15088.6 CDS28313.1 - 7.6 6.2 5.6 7 6.4 1.5 2.7 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Prenyltrans PF00432.21 CDS28314.1 - 2e-63 209.8 7.1 2.6e-14 52.6 0.0 5.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CDS28314.1 - 3.9e-06 26.2 0.0 0.0022 17.2 0.0 2.5 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CDS28314.1 - 2e-05 23.8 0.0 0.36 9.9 0.0 3.6 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 CDS28314.1 - 0.072 12.1 0.0 9.6 5.1 0.0 2.6 2 1 0 2 2 2 0 A-macroglobulin TED domain Integrin_alpha2 PF08441.12 CDS28315.1 - 3.7e-06 26.1 0.0 5.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CDS28315.1 - 6.5e-05 23.0 1.3 0.006 16.7 0.0 3.4 3 0 0 3 3 3 1 FG-GAP repeat FG-GAP_2 PF14312.6 CDS28315.1 - 0.071 13.4 1.9 37 4.7 0.0 3.3 3 0 0 3 3 3 0 FG-GAP repeat Plus-3 PF03126.18 CDS28316.1 - 3e-30 105.0 0.1 7.9e-30 103.6 0.1 1.8 1 0 0 1 1 1 1 Plus-3 domain ERCC4 PF02732.15 CDS28316.1 - 1.7e-13 51.0 0.0 1.7e-13 51.0 0.0 2.4 3 0 0 3 3 3 1 ERCC4 domain DnaJ PF00226.31 CDS28317.1 - 3.2e-22 78.4 0.5 1.1e-21 76.7 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain Homeodomain PF00046.29 CDS28318.1 - 2.9e-21 75.1 0.7 5.7e-21 74.1 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS28318.1 - 0.042 13.7 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain RVT_1 PF00078.27 CDS28319.1 - 0.0011 18.5 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDS28319.1 - 0.038 13.8 0.4 0.16 11.8 0.2 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase EGF_2 PF07974.13 CDS28320.1 - 0.00032 21.0 2.2 0.00055 20.2 2.2 1.4 1 1 0 1 1 1 1 EGF-like domain DSL PF01414.19 CDS28320.1 - 0.065 13.5 0.4 0.065 13.5 0.4 1.8 1 1 1 2 2 2 0 Delta serrate ligand NPDC1 PF06809.11 CDS28320.1 - 0.071 12.2 0.2 0.083 11.9 0.2 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) EGF_Tenascin PF18720.1 CDS28320.1 - 2 8.6 7.5 0.28 11.3 1.3 2.4 1 1 1 2 2 2 0 Tenascin EGF domain EGF_2 PF07974.13 CDS28321.1 - 0.00016 21.9 2.4 0.0005 20.4 2.4 1.8 1 1 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 CDS28321.1 - 0.0015 18.5 2.8 0.27 11.3 0.8 2.4 1 1 1 2 2 2 2 Tenascin EGF domain EGF PF00008.27 CDS28321.1 - 0.015 15.6 5.2 0.058 13.7 5.2 2.0 1 1 0 1 1 1 0 EGF-like domain DSL PF01414.19 CDS28321.1 - 0.023 15.0 0.5 0.023 15.0 0.5 2.0 1 1 1 2 2 2 0 Delta serrate ligand Laminin_EGF PF00053.24 CDS28321.1 - 0.22 11.7 4.8 0.55 10.4 4.8 1.7 1 1 0 1 1 1 0 Laminin EGF domain Dynein_light PF01221.18 CDS28322.2 - 4.9e-17 62.0 0.1 5.6e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2570 PF10828.8 CDS28322.2 - 0.056 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PWWP PF00855.17 CDS28323.1 - 2.4e-12 47.1 0.2 1.1e-11 45.0 0.2 2.2 1 0 0 1 1 1 1 PWWP domain APG6 PF04111.12 CDS28324.1 - 1.5e-50 171.6 0.0 4.2e-50 170.2 0.0 1.7 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 CDS28324.1 - 1.1e-22 80.9 23.2 1.1e-22 80.9 23.2 1.8 2 1 0 2 2 1 1 Apg6 coiled-coil region ATG16 PF08614.11 CDS28324.1 - 9.9e-05 22.6 12.9 0.00015 22.0 12.9 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 CDS28324.1 - 0.0099 15.0 6.8 0.023 13.8 6.8 1.8 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 CDS28324.1 - 0.011 15.8 15.6 0.022 14.8 15.7 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Myosin_tail_1 PF01576.19 CDS28324.1 - 0.016 13.0 15.2 0.022 12.6 15.2 1.1 1 0 0 1 1 1 0 Myosin tail GIT_CC PF16559.5 CDS28324.1 - 0.025 14.5 4.8 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 CDS28324.1 - 0.03 13.7 15.4 0.064 12.6 15.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Gin PF10764.9 CDS28324.1 - 0.067 13.2 1.4 7.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DUF2201_N PF13203.6 CDS28324.1 - 0.073 12.7 1.7 0.11 12.0 1.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ADIP PF11559.8 CDS28324.1 - 0.093 12.8 16.8 0.12 12.4 15.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CDS28324.1 - 0.18 11.2 4.0 0.26 10.6 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 CDS28324.1 - 0.18 12.2 9.8 0.4 11.1 9.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 CDS28324.1 - 0.31 11.3 10.1 0.82 9.9 10.1 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 CDS28324.1 - 0.34 9.8 14.9 0.55 9.1 14.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein MPS2 PF17060.5 CDS28324.1 - 0.55 9.4 7.6 0.91 8.7 7.6 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Cep57_CLD PF14073.6 CDS28324.1 - 0.63 10.0 17.4 0.26 11.3 14.0 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 ZapB PF06005.12 CDS28324.1 - 1.1 9.7 18.5 4.1 7.9 7.8 3.4 2 1 1 3 3 3 0 Cell division protein ZapB FAM76 PF16046.5 CDS28324.1 - 1.2 8.4 7.1 3.6 6.9 6.5 2.0 2 0 0 2 2 2 0 FAM76 protein YabA PF06156.13 CDS28324.1 - 1.4 9.6 9.8 8.4 7.1 8.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA PEARLI-4 PF05278.12 CDS28324.1 - 1.9 8.0 9.6 1.3 8.6 6.3 2.3 3 1 0 3 3 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Jnk-SapK_ap_N PF09744.9 CDS28324.1 - 2.2 8.5 17.4 1.3 9.2 15.4 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 CDS28324.1 - 2.2 9.0 12.4 18 6.1 7.7 3.4 2 1 0 3 3 3 0 SlyX DivIC PF04977.15 CDS28324.1 - 2.4 8.0 12.9 5.3 6.9 8.2 2.9 2 1 1 3 3 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 CDS28324.1 - 2.5 7.6 10.2 4.4 6.8 10.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 CDS28324.1 - 3.4 6.1 7.1 5.9 5.3 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cnn_1N PF07989.11 CDS28324.1 - 3.8 7.7 11.4 5.8 7.2 3.9 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 CDS28324.1 - 4 7.5 13.1 6.8 6.8 13.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 CDS28324.1 - 4.6 7.0 12.2 5 6.9 10.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) G-patch PF01585.23 CDS28325.1 - 3.1e-13 49.4 2.1 7.2e-13 48.2 2.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS28325.1 - 0.00034 20.6 0.1 0.00084 19.4 0.1 1.7 1 0 0 1 1 1 1 G-patch domain tRNA-synt_2b PF00587.25 CDS28326.1 - 1.8e-38 132.3 0.0 3.4e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDS28326.1 - 9e-15 54.8 0.5 9e-15 54.8 0.5 4.0 3 1 1 4 4 4 1 Seryl-tRNA synthetase N-terminal domain GATase PF00117.28 CDS28327.1 - 1.5e-36 126.0 0.0 4.3e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 CDS28327.1 - 1.1e-16 60.6 0.0 2.9e-09 36.9 0.0 3.2 2 1 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.17 CDS28327.1 - 1.3e-11 44.2 0.1 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CDS28327.1 - 9.4e-11 41.9 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 CDS28327.1 - 8.5e-06 25.4 0.2 3.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CDS28327.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 CDS28327.1 - 0.06 13.1 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 PP-loop family ThiI PF02568.14 CDS28327.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) DJ-1_PfpI PF01965.24 CDS28327.1 - 0.17 11.6 0.0 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 DJ-1/PfpI family RasGEF PF00617.19 CDS28328.2 - 1.3e-22 80.9 1.0 2.7e-14 53.8 0.0 2.8 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 CDS28328.2 - 0.0019 18.4 0.1 0.0057 16.9 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Kin17_mid PF10357.9 CDS28330.1 - 1e-42 145.0 0.3 2.4e-42 143.8 0.3 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CDS28330.1 - 6.6e-15 55.0 0.6 1.5e-14 53.8 0.6 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain PP1_bind PF15276.6 CDS28330.1 - 2.5e-10 40.5 2.2 2.5e-10 40.5 2.2 4.1 2 0 0 2 2 2 1 Protein phosphatase 1 binding zf-met PF12874.7 CDS28330.1 - 0.0013 19.1 6.6 0.0027 18.1 6.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS28330.1 - 0.02 15.2 5.9 0.042 14.2 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C4 PF00105.18 CDS28331.1 - 3.2e-21 75.5 10.8 8.8e-21 74.1 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS28331.1 - 3e-05 23.7 0.0 0.0005 19.7 0.0 2.3 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor K_channel_TID PF07941.11 CDS28331.1 - 0.084 13.3 5.4 0.22 12.0 5.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain C1_1 PF00130.22 CDS28331.1 - 8.7 6.3 7.8 0.33 10.9 1.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tau95 PF09734.9 CDS28332.1 - 1e-32 113.9 0.6 1.9e-32 113.0 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain WD40 PF00400.32 CDS28332.1 - 3.4e-29 100.5 22.0 0.0012 19.7 0.0 10.0 9 1 0 9 9 9 7 WD domain, G-beta repeat Tau95_N PF17682.1 CDS28332.1 - 3.6e-19 69.2 0.0 1.4e-18 67.3 0.0 2.0 1 1 0 1 1 1 1 Tau95 Triple barrel domain ANAPC4_WD40 PF12894.7 CDS28332.1 - 6.4e-07 29.6 3.1 10 6.5 0.0 7.2 6 1 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 CDS28332.1 - 0.25 9.7 1.6 2.3 6.5 0.1 2.2 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family NHL PF01436.21 CDS28333.1 - 1.8e-22 78.2 7.1 8e-05 22.5 0.0 6.6 6 0 0 6 6 6 4 NHL repeat DUF5128 PF17170.4 CDS28333.1 - 4.9e-15 55.5 0.1 1.7e-06 27.4 0.0 3.8 1 1 2 3 3 3 3 6-bladed beta-propeller DUF4934 PF16288.5 CDS28333.1 - 1.1e-07 31.7 1.1 0.0035 17.3 0.1 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4934) Filamin PF00630.19 CDS28333.1 - 6.2e-05 23.8 1.0 0.00015 22.5 0.5 2.0 2 0 0 2 2 1 1 Filamin/ABP280 repeat SGL PF08450.12 CDS28333.1 - 0.00024 20.8 0.0 0.2 11.2 0.1 4.2 1 1 2 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 CDS28333.1 - 0.00063 19.7 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Arylesterase PF01731.20 CDS28333.1 - 0.0029 17.8 0.2 0.02 15.1 0.1 2.5 2 1 0 2 2 2 1 Arylesterase Med9 PF07544.13 CDS28333.1 - 0.018 15.1 3.3 0.86 9.7 0.0 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SBBP PF06739.11 CDS28333.1 - 0.029 14.4 0.8 0.65 10.1 0.2 2.5 2 0 0 2 2 2 0 Beta-propeller repeat PIN_12 PF16289.5 CDS28333.1 - 0.046 14.2 1.4 0.086 13.3 1.4 1.4 1 0 0 1 1 1 0 PIN domain PQQ_2 PF13360.6 CDS28333.1 - 0.083 12.5 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain CENP-H PF05837.12 CDS28333.1 - 0.15 12.5 1.4 0.29 11.6 1.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2072 PF09845.9 CDS28333.1 - 0.75 10.1 3.0 0.98 9.7 0.1 2.5 3 0 0 3 3 3 0 Zn-ribbon containing protein CoA_binding PF02629.19 CDS28334.1 - 1.2e-30 106.0 0.6 3.3e-30 104.6 0.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CDS28334.1 - 5.2e-26 91.3 0.1 1e-25 90.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CDS28334.1 - 4.5e-09 36.2 0.0 8.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CDS28334.1 - 0.0089 16.5 0.0 0.026 15.0 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain RabGAP-TBC PF00566.18 CDS28335.1 - 1.1e-31 110.2 1.0 2.4e-31 109.1 1.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CDS28336.1 - 0.0016 17.9 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HA2 PF04408.23 CDS28337.1 - 2.6e-24 85.6 0.1 2.6e-24 85.6 0.1 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDS28337.1 - 1.1e-21 76.9 0.1 2.7e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDS28337.1 - 3e-12 46.9 0.0 6.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS28337.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDS28337.1 - 2.5e-05 24.7 0.0 6.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS28337.1 - 0.0021 18.3 0.1 0.012 15.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 CDS28337.1 - 0.0063 16.2 0.0 0.02 14.6 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CDS28337.1 - 0.01 16.3 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDS28337.1 - 0.019 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDS28337.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_IclR PF09339.10 CDS28337.1 - 0.045 13.6 0.4 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain ABC_tran PF00005.27 CDS28337.1 - 0.069 13.7 0.1 0.45 11.0 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Flavi_DEAD PF07652.14 CDS28337.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 CDS28337.1 - 0.097 12.7 0.0 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDS28337.1 - 0.097 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDS28337.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 CDS28337.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 CDS28337.1 - 0.21 10.4 0.8 1.8 7.4 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain HECT PF00632.25 CDS28338.2 - 1.2e-90 304.1 0.0 1.8e-90 303.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Eapp_C PF10238.9 CDS28339.1 - 5.7e-32 110.9 13.7 1.7e-24 86.6 3.7 3.0 2 1 1 3 3 3 2 E2F-associated phosphoprotein pRN1_helical PF13010.6 CDS28339.1 - 0.36 10.8 2.8 0.56 10.2 0.0 2.2 2 1 0 2 2 2 0 Primase helical domain Cgr1 PF03879.14 CDS28339.1 - 0.39 11.1 3.8 0.63 10.4 3.8 1.3 1 0 0 1 1 1 0 Cgr1 family zf-B_box PF00643.24 CDS28339.1 - 3 8.1 8.4 5.6 7.2 4.0 2.5 2 0 0 2 2 2 0 B-box zinc finger Vitellogenin_N PF01347.22 CDS28340.1 - 0.00026 19.5 3.9 0.00035 19.1 1.3 2.3 3 0 0 3 3 3 1 Lipoprotein amino terminal region Pkinase PF00069.25 CDS28341.2 - 6.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_3 PF13927.6 CDS28342.1 - 2.6e-07 31.1 0.0 3.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS28342.1 - 2.6e-06 27.5 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS28342.1 - 9.9e-06 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS28342.1 - 4.9e-05 23.6 0.0 7.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDS28342.1 - 5.7e-05 23.3 0.2 0.00074 19.7 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF3715 PF12509.8 CDS28343.1 - 1.4e-23 83.5 0.2 1.7e-21 76.8 0.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3715) MFS_1_like PF12832.7 CDS28344.1 - 8.4e-87 291.5 7.9 1.1e-86 291.1 7.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CDS28344.1 - 3e-21 75.8 38.4 1.7e-15 56.8 13.0 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CDS28344.1 - 7.9e-12 44.9 20.0 2.2e-08 33.5 3.1 3.2 3 0 0 3 3 3 3 Nucleoside H+ symporter MFS_2 PF13347.6 CDS28344.1 - 1.1e-07 30.8 23.1 6.5e-05 21.7 0.6 4.3 3 2 0 4 4 4 4 MFS/sugar transport protein LacY_symp PF01306.19 CDS28344.1 - 7.5e-05 21.7 21.4 0.00032 19.6 0.5 3.1 3 0 0 3 3 3 2 LacY proton/sugar symporter PAP_central PF04928.17 CDS28345.1 - 7.7e-33 113.5 0.1 2e-32 112.1 0.1 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 CDS28345.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PAP_RNA-bind PF04926.15 CDS28345.1 - 0.2 11.3 2.8 1.2 8.7 1.9 2.2 1 1 1 2 2 2 0 Poly(A) polymerase predicted RNA binding domain HTH_48 PF17906.1 CDS28346.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase RPN13_C PF16550.5 CDS28347.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 UCH-binding domain TPR_14 PF13428.6 CDS28348.2 - 1.8e-13 50.1 0.2 0.00014 22.4 0.0 6.1 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS28348.2 - 1.6e-11 43.3 3.6 2.2 8.6 0.0 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS28348.2 - 4.3e-11 42.1 2.2 0.18 11.7 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS28348.2 - 1.2e-09 37.6 8.3 0.27 11.5 0.9 7.8 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28348.2 - 1.2e-08 34.7 3.2 3.9 8.1 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28348.2 - 4.8e-07 30.2 5.2 0.0039 17.7 0.0 5.1 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS28348.2 - 4.6e-06 26.2 0.0 0.091 12.5 0.0 4.4 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 CDS28348.2 - 3.5e-05 24.0 6.7 1.4 9.2 0.3 6.1 4 1 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28348.2 - 4.6e-05 23.5 0.0 0.69 10.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28348.2 - 0.001 19.0 0.6 1.2 9.3 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS28348.2 - 0.0012 19.5 0.1 0.054 14.2 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDS28348.2 - 0.0025 18.3 3.7 9.4 7.1 0.1 5.7 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDS28348.2 - 0.019 14.2 0.1 5.8 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FUSC-like PF12805.7 CDS28348.2 - 0.15 11.1 1.4 0.18 10.9 0.1 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PIP5K PF01504.18 CDS28349.2 - 7.5e-92 307.4 0.1 9.8e-37 126.7 0.0 4.3 2 2 2 4 4 4 4 Phosphatidylinositol-4-phosphate 5-Kinase PIGA PF08288.12 CDS28349.2 - 3.4e-73 242.3 2.7 3.5e-35 120.5 0.2 3.3 2 0 0 2 2 2 2 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CDS28349.2 - 3.1e-55 186.8 4.9 1e-26 93.9 0.4 2.8 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDS28349.2 - 4.7e-39 133.7 0.0 4.1e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDS28349.2 - 7.1e-37 126.8 1.3 5.1e-17 62.6 0.1 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDS28349.2 - 5.4e-20 72.4 9.9 4.7e-09 36.9 0.0 4.2 4 0 0 4 4 4 2 Glycosyl transferase 4-like domain Cpn60_TCP1 PF00118.24 CDS28349.2 - 2.8e-16 59.2 0.7 5.5e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family DEP PF00610.21 CDS28349.2 - 2.9e-08 33.6 0.0 7.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_trans_1_2 PF13524.6 CDS28349.2 - 3e-05 24.3 0.1 0.7 10.3 0.0 3.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CDS28349.2 - 0.0011 18.7 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 2 Starch synthase catalytic domain SIS PF01380.22 CDS28349.2 - 0.14 12.0 0.0 30 4.5 0.0 2.5 2 0 0 2 2 2 0 SIS domain KdpC PF02669.15 CDS28349.2 - 0.27 11.1 4.1 4.8 7.0 0.1 2.7 2 0 0 2 2 2 0 K+-transporting ATPase, c chain SARA PF11409.8 CDS28349.2 - 9.5 6.5 8.4 36 4.7 1.1 2.8 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) Metallophos PF00149.28 CDS28350.1 - 7.4e-29 101.7 0.4 9.4e-29 101.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDS28350.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 CDS28350.1 - 0.0019 18.6 0.2 0.0032 17.9 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PAP_central PF04928.17 CDS28351.1 - 6.9e-94 313.5 0.0 1e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDS28351.1 - 7.4e-18 64.8 1.4 1.8e-16 60.2 0.4 2.8 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDS28351.1 - 2.6e-07 30.8 0.0 7.9e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain mTERF PF02536.14 CDS28352.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 mTERF ENT PF03735.14 CDS28354.1 - 1.8e-25 88.8 0.2 4e-25 87.7 0.2 1.6 1 0 0 1 1 1 1 ENT domain PAP_central PF04928.17 CDS28355.1 - 7e-06 25.2 0.0 0.00022 20.3 0.0 2.1 1 1 1 2 2 2 2 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 CDS28355.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain IMUP PF15761.5 CDS28355.1 - 0.012 16.3 4.6 0.022 15.5 4.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CDS28355.1 - 0.034 14.7 2.7 0.057 14.0 2.7 1.2 1 0 0 1 1 1 0 Dehydrin IIGP PF05049.13 CDS28356.1 - 0.019 14.1 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) OST-HTH PF12872.7 CDS28356.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain HTH_48 PF17906.1 CDS28357.2 - 9.2e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 HTH domain in Mos1 transposase AAA PF00004.29 CDS28358.2 - 3.4e-26 92.2 0.1 3.4e-26 92.2 0.1 2.7 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDS28358.2 - 9.1e-22 76.8 0.3 1.7e-21 75.9 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDS28358.2 - 2.1e-10 40.2 0.2 6.1e-10 38.8 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDS28358.2 - 0.019 15.1 0.2 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Cdh1_DBD_1 PF18196.1 CDS28358.2 - 0.32 11.3 3.1 40 4.6 1.7 3.3 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Ku_PK_bind PF08785.11 CDS28359.2 - 0.085 13.0 0.2 0.34 11.1 0.2 2.1 1 0 0 1 1 1 0 Ku C terminal domain like PAX PF00292.18 CDS28361.2 - 3.3e-34 117.5 1.2 5.5e-34 116.8 1.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.6 CDS28361.2 - 3.8e-07 29.7 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CDS28361.2 - 0.0014 18.6 0.3 0.0029 17.6 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CDS28361.2 - 0.0026 17.9 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 CDS28361.2 - 0.095 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_38 PF13936.6 CDS28361.2 - 0.15 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_1 PF00583.25 CDS28363.1 - 3.4e-11 43.4 0.0 4.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS28363.1 - 8.7e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS28363.1 - 1.1e-07 31.8 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDS28363.1 - 1.3e-06 28.2 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CDS28363.1 - 0.00044 20.3 0.1 0.00059 19.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDP-OH_P_transf PF01066.21 CDS28364.1 - 4.6e-19 68.9 0.2 4.6e-19 68.9 0.2 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase 60KD_IMP PF02096.20 CDS28365.1 - 3.7e-28 98.5 7.5 5.1e-28 98.1 7.5 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S10 PF00338.22 CDS28366.2 - 2.7e-10 40.4 0.0 7.7e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e SET PF00856.28 CDS28367.1 - 4.1e-07 30.5 0.0 1.4e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 SET domain zinc-ribbons_6 PF07191.12 CDS28367.1 - 0.051 13.6 4.5 0.12 12.4 4.5 1.6 1 0 0 1 1 1 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 CDS28367.1 - 2.4 8.2 6.3 0.6 10.1 0.6 2.3 1 1 1 2 2 2 0 PhnA Zinc-Ribbon ASC PF00858.24 CDS28368.1 - 1e-66 225.8 16.7 7.9e-66 222.8 16.7 1.9 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel RVT_1 PF00078.27 CDS28369.1 - 0.00014 21.5 0.1 0.00014 21.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NT-C2 PF10358.9 CDS28372.1 - 0.16 11.7 0.8 0.84 9.3 0.8 2.0 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins zf-RING_9 PF13901.6 CDS28373.1 - 5e-51 173.6 5.7 9.9e-51 172.7 5.7 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 CDS28373.1 - 0.015 15.2 3.8 0.015 15.2 3.8 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 CDS28373.1 - 0.1 12.6 3.5 0.69 9.9 0.6 3.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid FtsJ PF01728.19 CDS28374.2 - 3.2e-37 128.3 0.0 7.2e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CDS28374.2 - 3.3e-35 121.7 22.7 3.3e-35 121.7 22.7 3.8 2 1 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 CDS28374.2 - 9.5e-29 100.3 13.9 9.5e-29 100.3 13.9 5.4 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) TPK_catalytic PF04263.16 CDS28374.2 - 4.6 7.3 6.0 22 5.1 1.4 3.0 2 1 1 3 3 3 0 Thiamin pyrophosphokinase, catalytic domain RT_RNaseH_2 PF17919.1 CDS28375.1 - 2.3e-25 88.5 0.2 3.6e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS28375.1 - 1.9e-24 86.0 0.1 3.4e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS28375.1 - 3.7e-06 26.6 0.0 0.0017 17.9 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 CDS28376.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28376.1 - 9.5e-37 126.7 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS28376.1 - 2e-06 27.3 0.0 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDS28376.1 - 0.0026 17.1 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMAP PF15477.6 CDS28378.1 - 1.1e-11 45.6 0.1 1.1e-11 45.6 0.1 3.2 3 1 0 3 3 3 1 Small acidic protein family DUF3460 PF11943.8 CDS28378.1 - 0.048 13.9 0.5 0.16 12.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) zf-C3HC4_3 PF13920.6 CDS28379.1 - 7.1e-08 32.2 7.1 7.1e-08 32.2 7.1 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS28379.1 - 4.3e-07 29.7 6.3 4.3e-07 29.7 6.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS28379.1 - 5.2e-07 29.6 6.4 5.2e-07 29.6 6.4 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS28379.1 - 2.5e-06 27.2 11.7 2.5e-06 27.2 11.7 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS28379.1 - 3.8e-06 27.1 10.4 3.8e-06 27.1 10.4 2.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDS28379.1 - 3.3e-05 24.0 8.6 3.3e-05 24.0 8.6 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDS28379.1 - 5.5e-05 23.0 9.2 5.5e-05 23.0 9.2 2.5 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS28379.1 - 0.00039 20.2 10.2 0.00039 20.2 10.2 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CDS28379.1 - 0.00043 20.3 2.4 0.00043 20.3 2.4 2.1 2 1 1 3 3 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 CDS28379.1 - 0.0011 18.7 4.8 0.0011 18.7 4.8 2.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C4_Topoisom PF01396.19 CDS28379.1 - 0.0066 16.2 6.2 0.029 14.2 0.2 3.4 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Rad50_zn_hook PF04423.14 CDS28379.1 - 0.039 13.8 1.8 1.7 8.6 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Rtf2 PF04641.12 CDS28379.1 - 0.34 10.2 2.0 0.48 9.7 2.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-MIZ PF02891.20 CDS28379.1 - 0.59 9.9 10.2 4.5 7.1 10.2 2.4 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.6 CDS28379.1 - 1.8 8.5 12.1 0.036 13.9 4.8 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TerY_C PF15616.6 CDS28379.1 - 4.9 7.3 8.8 0.26 11.4 2.9 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_UBOX PF13445.6 CDS28380.1 - 3.6e-08 33.3 6.5 1.1e-07 31.7 6.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS28380.1 - 1.9e-06 27.7 6.1 4.9e-06 26.3 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDS28380.1 - 2.2e-06 27.7 8.7 8e-06 25.9 8.7 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CDS28380.1 - 2.6e-06 27.1 6.2 8.3e-06 25.5 6.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS28380.1 - 0.0003 20.6 4.0 0.0003 20.6 4.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS28380.1 - 0.00088 19.6 7.3 0.00088 19.6 7.3 2.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDS28380.1 - 0.0025 17.7 6.3 0.0084 16.0 6.3 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 CDS28380.1 - 0.016 15.1 5.1 0.034 14.0 5.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_2 PF14608.6 CDS28380.1 - 0.12 12.9 13.1 0.49 11.0 3.8 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger HLH PF00010.26 CDS28381.1 - 0.00026 20.9 0.6 0.00026 20.9 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2956 PF11169.8 CDS28381.1 - 3 8.1 4.7 0.71 10.1 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) RVT_1 PF00078.27 CDS28385.1 - 2e-29 102.7 0.0 3.4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDS28385.1 - 0.15 12.6 0.0 0.52 10.9 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease EF-hand_7 PF13499.6 CDS28386.1 - 6e-24 84.3 8.1 3.2e-12 46.7 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS28386.1 - 9.6e-22 74.9 11.3 3.7e-06 26.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS28386.1 - 6.4e-20 69.3 8.1 4e-06 26.3 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS28386.1 - 2.8e-11 43.1 11.9 3.7e-07 29.9 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDS28386.1 - 3.2e-11 42.2 12.4 0.00033 20.0 0.2 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 CDS28386.1 - 4.3e-07 30.2 4.3 0.00015 22.1 0.7 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS28386.1 - 6.1e-07 29.3 2.5 0.011 15.6 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDS28386.1 - 0.00011 22.5 1.6 0.038 14.3 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 CDS28386.1 - 0.00028 21.7 0.2 0.21 12.5 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 CDS28386.1 - 0.014 15.3 0.7 22 4.9 0.0 3.3 2 2 1 3 3 3 0 Caleosin related protein Death PF00531.22 CDS28386.1 - 0.057 13.6 0.3 4.7 7.4 0.1 3.1 1 1 1 2 2 2 0 Death domain Rop PF01815.16 CDS28386.1 - 0.21 11.5 1.7 0.41 10.5 0.3 2.4 2 1 0 2 2 2 0 Rop protein 7tm_1 PF00001.21 CDS28388.1 - 1e-19 70.9 19.0 1e-19 70.9 19.0 2.3 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS28388.1 - 1.4 8.5 25.1 2.4 7.7 15.0 2.7 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF1664 PF07889.12 CDS28389.2 - 5.7 7.0 25.7 0.29 11.2 6.1 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 CDS28391.1 - 0.042 13.7 1.5 0.038 13.8 0.5 1.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain OSCP PF00213.18 CDS28391.1 - 0.4 10.8 3.4 0.89 9.7 0.6 2.2 1 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit CBFD_NFYB_HMF PF00808.23 CDS28392.1 - 1.2e-19 70.4 0.3 2.6e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS28392.1 - 1.9e-14 54.2 0.6 1.9e-14 54.2 0.6 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CDS28392.1 - 0.0062 16.8 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Arf PF00025.21 CDS28393.1 - 5.8e-67 224.5 0.2 6.6e-67 224.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDS28393.1 - 1.5e-11 44.1 0.8 2.6e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CDS28393.1 - 7.1e-11 42.4 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDS28393.1 - 8.8e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CDS28393.1 - 1.2e-08 34.7 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDS28393.1 - 2.3e-08 33.7 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDS28393.1 - 1.3e-06 28.4 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CDS28393.1 - 0.0053 16.2 0.1 0.0084 15.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein GST_C_3 PF14497.6 CDS28394.1 - 2.3e-09 37.3 0.0 3.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS28394.1 - 7.6e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDS28394.1 - 0.00017 21.7 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDS28394.1 - 0.00059 19.8 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDS28394.1 - 0.0023 18.3 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDS28394.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NPDC1 PF06809.11 CDS28395.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) DUF4573 PF15140.6 CDS28396.2 - 0.012 15.4 22.4 0.018 14.9 22.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) Amelogenin PF02948.15 CDS28396.2 - 0.026 15.2 33.3 7e+02 0.7 33.3 2.5 1 1 0 1 1 1 0 Amelogenin MFS_1 PF07690.16 CDS28397.1 - 4.6e-29 101.4 5.0 5.1e-29 101.3 5.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS28397.1 - 6.3e-06 25.3 0.5 7.5e-06 25.1 0.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Ribosomal_S27 PF01599.19 CDS28398.1 - 1.2e-23 82.9 3.6 2.4e-23 82.0 3.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CDS28398.1 - 1.1e-09 37.9 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS28398.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_C_2 PF01322.20 CDS28398.1 - 0.028 15.3 0.7 2.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C' Ubiquitin_4 PF18036.1 CDS28398.1 - 0.059 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF5352 PF17303.2 CDS28398.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) TPT PF03151.16 CDS28399.1 - 5.5e-11 42.4 15.8 6.3e-11 42.2 15.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDS28399.1 - 0.00061 20.0 7.2 0.00061 20.0 7.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family PHR PF08005.12 CDS28400.2 - 3.2e-46 157.7 0.1 9.7e-46 156.2 0.1 1.9 1 0 0 1 1 1 1 PHR domain BTB PF00651.31 CDS28400.2 - 2.9e-30 104.7 5.6 1.4e-10 41.4 0.1 5.5 4 1 1 5 5 5 5 BTB/POZ domain BACK PF07707.15 CDS28400.2 - 8.2e-12 45.1 1.4 2.6e-10 40.3 0.4 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch LolA_2 PF16584.5 CDS28400.2 - 0.0031 17.4 0.5 2.7 7.8 0.0 2.6 2 0 0 2 2 2 2 Outer membrane lipoprotein carrier protein LolA Antimicrobial10 PF08105.11 CDS28400.2 - 0.022 14.8 4.7 3 8.0 0.4 2.6 2 0 0 2 2 2 0 Metchnikowin family UFD1 PF03152.14 CDS28401.1 - 4.1e-71 238.0 0.0 5.5e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 CDS28401.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Nmad2 PF18753.1 CDS28402.1 - 0.21 11.0 3.3 0.42 10.0 3.3 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 CKS PF01111.19 CDS28403.1 - 2e-36 124.1 1.0 2.4e-36 123.8 1.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 CDS28403.1 - 0.029 14.1 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) SH3_4 PF06347.13 CDS28403.1 - 0.14 12.0 0.1 0.63 9.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain HMG_box PF00505.19 CDS28405.1 - 1.2e-32 112.1 1.3 2.8e-19 69.3 0.3 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS28405.1 - 9.4e-27 93.4 2.8 4.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 HMG-box domain UNC80 PF15778.5 CDS28406.1 - 3.9e-27 95.1 0.0 7.3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Cation channel complex component UNC80 PAP2_C PF14360.6 CDS28407.1 - 1.3e-25 89.7 6.4 1.3e-25 89.7 6.4 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CDS28407.1 - 1.4e-06 28.1 5.4 1.4e-06 28.1 5.4 1.9 1 1 0 1 1 1 1 PAP2 superfamily SAM_1 PF00536.30 CDS28407.1 - 3.4e-06 27.4 0.3 6.5e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS28407.1 - 0.00055 20.0 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EGF_CA PF07645.15 CDS28408.1 - 1.2e-78 259.1 170.2 1.7e-09 37.7 7.5 15.8 14 2 1 15 15 15 11 Calcium-binding EGF domain cEGF PF12662.7 CDS28408.1 - 3.6e-53 177.0 98.8 2.1e-10 40.4 0.6 14.7 15 0 0 15 15 15 11 Complement Clr-like EGF-like EGF_3 PF12947.7 CDS28408.1 - 1.6e-14 53.8 112.4 0.0015 18.6 3.0 13.4 11 2 0 11 11 11 8 EGF domain FXa_inhibition PF14670.6 CDS28408.1 - 2.2e-10 40.6 148.8 1.7e-07 31.4 7.3 15.5 12 4 2 14 14 14 5 Coagulation Factor Xa inhibitory site EGF PF00008.27 CDS28408.1 - 1.4e-05 25.3 11.6 0.00094 19.4 0.3 15.7 15 1 0 15 15 15 6 EGF-like domain hEGF PF12661.7 CDS28408.1 - 0.0095 16.5 2.9 0.0095 16.5 2.9 16.6 16 1 0 16 16 16 7 Human growth factor-like EGF DNTTIP1_dimer PF18192.1 CDS28410.1 - 5e-17 62.0 0.2 8.9e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain VHL PF01847.16 CDS28410.1 - 0.14 12.1 0.1 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 VHL beta domain AAA PF00004.29 CDS28411.1 - 1.9e-43 148.0 0.0 4.6e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDS28411.1 - 7.1e-10 38.7 0.2 3.4e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDS28411.1 - 7.6e-10 38.4 0.1 1.8e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDS28411.1 - 1.9e-08 34.6 0.0 4.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDS28411.1 - 1.1e-07 31.9 0.1 3.6e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS28411.1 - 1.2e-05 25.8 0.1 0.0055 17.1 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CDS28411.1 - 0.00018 21.3 0.0 0.00058 19.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDS28411.1 - 0.00019 20.7 0.2 0.00048 19.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CDS28411.1 - 0.00023 21.1 0.1 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 CDS28411.1 - 0.00031 21.0 0.6 0.044 14.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CDS28411.1 - 0.00051 20.1 0.1 0.0061 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDS28411.1 - 0.00072 19.0 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDS28411.1 - 0.00073 19.9 0.0 0.0021 18.4 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 CDS28411.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS28411.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDS28411.1 - 0.0019 17.9 0.1 0.0046 16.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CDS28411.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.8 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 CDS28411.1 - 0.0061 15.8 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 CDS28411.1 - 0.0081 16.2 0.0 0.15 12.1 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDS28411.1 - 0.014 15.3 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 CDS28411.1 - 0.016 14.9 0.4 0.87 9.3 0.0 2.9 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDS28411.1 - 0.04 13.4 0.1 0.28 10.7 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Viral_Hsp90 PF03225.14 CDS28411.1 - 0.072 11.6 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_3 PF07726.11 CDS28411.1 - 0.073 12.9 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CDS28411.1 - 0.077 12.4 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 CDS28411.1 - 0.083 13.4 0.0 0.32 11.5 0.0 2.1 3 0 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.12 CDS28411.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CDS28411.1 - 0.097 12.2 2.4 0.23 11.0 0.2 2.3 2 1 0 3 3 3 0 AAA domain Tmemb_185A PF10269.9 CDS28412.2 - 4.2e-27 95.4 21.9 6.5e-27 94.8 21.9 1.3 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Beach PF02138.18 CDS28413.2 - 6e-122 406.3 0.1 9.4e-122 405.7 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CDS28413.2 - 8.9e-17 61.2 14.9 0.00016 22.4 0.8 7.4 6 0 0 6 6 6 3 WD domain, G-beta repeat FYVE PF01363.21 CDS28413.2 - 3.2e-13 49.6 9.7 9.9e-13 48.0 9.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 CDS28413.2 - 3.8e-13 49.4 0.4 9e-13 48.2 0.4 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 CDS28413.2 - 0.0052 16.1 0.7 0.011 15.0 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Laminin_G_3 PF13385.6 CDS28413.2 - 0.0062 16.7 0.0 0.065 13.4 0.0 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.11 CDS28413.2 - 0.0066 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) IBR PF01485.21 CDS28413.2 - 0.15 12.3 9.9 0.027 14.7 5.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 CDS28413.2 - 1.4 9.1 8.8 5.6 7.2 8.8 2.1 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 CDS28413.2 - 2.3 8.4 5.1 10 6.3 5.1 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger Vitellogenin_N PF01347.22 CDS28414.2 - 4.2e-18 65.1 0.0 5.4e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Lipoprotein amino terminal region DUF1943 PF09172.11 CDS28414.2 - 9.5e-10 38.2 3.3 9.5e-10 38.2 3.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1943) Abhydrolase_1 PF00561.20 CDS28415.1 - 4.2e-23 82.3 0.0 2.9e-22 79.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDS28415.1 - 2e-17 64.5 0.0 5.1e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDS28415.1 - 2.5e-15 56.4 0.0 1e-14 54.4 0.0 1.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Ndr PF03096.14 CDS28415.1 - 5.9e-06 25.2 0.0 1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 CDS28415.1 - 2.3e-05 24.4 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 CDS28415.1 - 0.00017 21.0 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 CDS28415.1 - 0.00017 21.8 0.0 0.00076 19.7 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 CDS28415.1 - 0.0012 18.7 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 CDS28415.1 - 0.0043 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Putative esterase DUF1057 PF06342.12 CDS28415.1 - 0.0051 15.9 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 CDS28415.1 - 0.0069 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 CDS28415.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 CDS28415.1 - 0.058 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme BAAT_C PF08840.11 CDS28415.1 - 0.08 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Asp2 PF16929.5 CDS28415.1 - 0.095 11.7 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Accessory Sec system GspB-transporter PAF-AH_p_II PF03403.13 CDS28415.1 - 0.16 10.4 0.0 0.31 9.5 0.0 1.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 CDS28415.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 CDS28415.1 - 0.2 11.4 0.0 0.54 10.0 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SET PF00856.28 CDS28416.1 - 3.9e-09 37.1 0.0 7.7e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 SET domain ParcG PF10274.9 CDS28417.1 - 1.9e-10 41.2 0.0 2.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Dynein_light PF01221.18 CDS28418.1 - 1.1e-20 73.7 0.0 1.2e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CDS28418.1 - 0.084 13.5 0.1 0.15 12.7 0.0 1.4 2 0 0 2 2 2 0 Ground-like domain Dynein_light PF01221.18 CDS28419.2 - 2.4e-15 56.6 0.0 2.8e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Zip PF02535.22 CDS28421.1 - 5.3e-55 187.0 14.9 5.3e-55 187.0 14.9 3.8 2 2 1 3 3 3 1 ZIP Zinc transporter Pro_isomerase PF00160.21 CDS28421.1 - 1.7e-38 132.4 0.0 3.1e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Borrelia_P83 PF05262.11 CDS28421.1 - 5.9 5.3 28.2 9.2 4.6 28.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SCAMP PF04144.13 CDS28422.1 - 0.023 15.0 1.8 0.023 15.0 1.8 1.6 1 1 0 1 1 1 0 SCAMP family DUF565 PF04483.12 CDS28422.1 - 0.15 12.6 0.1 0.15 12.6 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF565) DUF2721 PF11026.8 CDS28422.1 - 0.58 10.0 13.5 1.1 9.1 9.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ArAE_2_N PF10337.9 CDS28422.1 - 0.58 9.1 6.1 0.75 8.8 6.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Dpy19 PF10034.9 CDS28422.1 - 0.6 8.3 3.6 0.66 8.1 3.6 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Dynein_light PF01221.18 CDS28424.1 - 2.4e-22 79.0 0.7 2.8e-22 78.8 0.7 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 TFIID-31kDa PF02291.15 CDS28424.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Dak2 PF02734.17 CDS28424.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 DAK2 domain BRO1 PF03097.18 CDS28425.1 - 2.1e-30 105.8 0.1 2.5e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain mRNA_decap_C PF16741.5 CDS28426.2 - 0.0012 18.1 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 mRNA-decapping enzyme C-terminus GGA_N-GAT PF18308.1 CDS28426.2 - 0.042 13.5 0.3 13 5.6 0.0 2.5 2 0 0 2 2 2 0 GGA N-GAT domain Zip PF02535.22 CDS28427.1 - 1.3e-53 182.4 5.8 1.9e-53 181.8 5.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RRM_1 PF00076.22 CDS28428.1 - 6.9e-18 64.2 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RINGv PF12906.7 CDS28429.1 - 4e-16 58.9 8.4 7.4e-16 58.0 8.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CDS28429.1 - 0.25 11.7 9.7 0.56 10.6 9.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 CDS28429.1 - 0.92 9.6 6.7 1.2 9.2 5.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PARP PF00644.20 CDS28432.2 - 8.7e-55 185.4 0.0 1.6e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Lig_chan PF00060.26 CDS28432.2 - 1e-47 161.7 0.4 2.4e-47 160.5 0.4 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel PARP_reg PF02877.14 CDS28432.2 - 4.4e-42 143.4 0.0 9.2e-42 142.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Lig_chan-Glu_bd PF10613.9 CDS28432.2 - 5.5e-28 97.5 0.0 1.1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site WGR PF05406.15 CDS28432.2 - 9.3e-27 92.9 3.4 2.5e-26 91.5 3.4 1.8 1 0 0 1 1 1 1 WGR domain ANF_receptor PF01094.28 CDS28432.2 - 5.1e-15 55.4 0.0 8.6e-05 21.8 0.0 3.5 3 0 0 3 3 3 3 Receptor family ligand binding region SBP_bac_3 PF00497.20 CDS28432.2 - 9e-15 54.7 0.0 3e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PucR PF07905.11 CDS28432.2 - 3.6e-10 40.1 0.0 0.11 12.7 0.0 4.8 4 0 0 4 4 4 2 Purine catabolism regulatory protein-like family VHS PF00790.19 CDS28432.2 - 9.6e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain PHF12_MRG_bd PF16737.5 CDS28432.2 - 0.0036 17.0 0.2 4.1 7.2 0.0 2.5 2 0 0 2 2 2 2 PHD finger protein 12 MRG binding domain Peptidase_M60_C PF18630.1 CDS28432.2 - 0.053 13.6 0.5 1e+02 3.1 0.0 3.5 3 0 0 3 3 3 0 Peptidase M60 C-terminal domain Peripla_BP_6 PF13458.6 CDS28432.2 - 0.073 12.7 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Periplasmic binding protein OST-HTH PF12872.7 CDS28433.1 - 3.5e-41 138.9 2.2 4.1e-11 42.5 0.0 7.1 7 0 0 7 7 7 5 OST-HTH/LOTUS domain PCI PF01399.27 CDS28433.1 - 8.3e-10 39.1 0.5 5.2e-09 36.6 0.0 2.8 2 0 0 2 2 2 1 PCI domain Ald_deCOase PF11266.8 CDS28433.1 - 0.13 12.0 0.0 0.95 9.1 0.0 2.2 2 0 0 2 2 2 0 Long-chain fatty aldehyde decarbonylase AAA_6 PF12774.7 CDS28434.1 - 3.3e-146 486.4 0.0 9.9e-146 484.9 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CDS28434.1 - 2.2e-126 422.8 8.0 2.2e-126 422.8 8.0 3.1 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDS28434.1 - 1.5e-123 412.8 0.2 1.5e-123 412.8 0.2 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CDS28434.1 - 8.1e-95 317.6 7.9 1.5e-94 316.7 0.1 4.4 6 0 0 6 6 6 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDS28434.1 - 1.1e-87 293.7 0.0 3e-87 292.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS28434.1 - 8.7e-81 270.2 5.2 3.9e-80 268.1 1.0 3.7 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS28434.1 - 2.1e-69 232.7 0.2 3.1e-63 212.6 0.0 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS28434.1 - 3.2e-48 163.7 0.1 8.3e-48 162.3 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS28434.1 - 4.5e-42 144.3 8.6 4.5e-42 144.3 8.6 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS28434.1 - 8.8e-40 135.5 1.3 1.5e-38 131.6 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CDS28434.1 - 6.2e-29 100.7 4.6 4.9e-26 91.3 0.6 4.7 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDS28434.1 - 2e-21 76.4 0.0 6.2e-09 36.0 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS28434.1 - 9.7e-18 64.2 0.5 6.3e-17 61.6 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 CDS28434.1 - 2.2e-08 34.7 0.5 0.4 11.1 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CDS28434.1 - 1.6e-06 28.4 0.9 0.41 10.9 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 CDS28434.1 - 4.2e-06 27.2 0.0 2.4 8.6 0.0 4.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDS28434.1 - 0.0007 19.4 1.7 2.5 7.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CDS28434.1 - 0.00085 18.8 0.0 0.085 12.2 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 CDS28434.1 - 0.0033 17.1 0.0 1.7 8.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 CDS28434.1 - 0.0069 16.1 0.1 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CDS28434.1 - 0.01 16.4 0.0 7.2 7.2 0.0 4.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CDS28434.1 - 0.06 13.7 0.2 4 7.9 0.0 3.4 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 CDS28434.1 - 0.074 13.1 1.2 29 4.7 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDS28434.1 - 0.098 12.4 0.8 4.5 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CDS28434.1 - 0.099 13.2 0.0 1.2 9.7 0.0 2.9 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 CDS28434.1 - 0.13 12.5 0.2 2.2 8.4 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDS28434.1 - 0.51 10.7 10.3 1.9 8.8 0.0 4.8 6 0 0 6 6 3 0 AAA domain AAA_25 PF13481.6 CDS28434.1 - 4 7.0 5.0 20 4.7 0.0 3.7 5 0 0 5 5 5 0 AAA domain CCDC144C PF14915.6 CDS28434.1 - 4 6.5 17.0 2.3 7.3 2.9 3.3 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region Vac_ImportDeg PF09783.9 CDS28435.1 - 1e-46 158.7 0.7 1.3e-46 158.4 0.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Peptidase_M24 PF00557.24 CDS28436.1 - 6.7e-51 173.0 0.4 1e-50 172.3 0.4 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDS28436.1 - 2.3e-20 72.6 0.0 5.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribosomal_L14e PF01929.17 CDS28437.1 - 2.7e-29 101.4 1.0 4.3e-29 100.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CDS28437.1 - 0.12 12.4 3.2 0.2 11.6 3.2 1.4 1 0 0 1 1 1 0 KOW motif PRP1_N PF06424.12 CDS28438.1 - 1.3e-55 187.9 8.5 1.3e-55 187.9 8.5 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDS28438.1 - 1.6e-25 87.6 24.5 0.00055 20.5 0.0 13.7 7 4 8 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28438.1 - 1.5e-17 63.8 7.4 3.6e-06 27.4 0.1 9.1 8 2 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 CDS28438.1 - 6.4e-06 26.0 4.1 0.053 13.2 0.3 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 CDS28438.1 - 5.1e-05 23.8 0.2 0.11 13.2 0.3 4.4 2 2 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 CDS28438.1 - 0.00012 22.2 3.0 0.51 10.3 0.0 5.2 8 0 0 8 8 8 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 CDS28438.1 - 0.00018 21.7 0.2 7.3 7.2 0.0 7.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS28438.1 - 0.0008 19.3 1.2 1.9e+02 2.6 0.1 7.4 8 1 1 9 9 9 0 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 CDS28438.1 - 0.019 14.9 0.4 1.8 8.6 0.0 3.6 3 1 1 4 4 4 0 ZNRF-3 Ectodomain TPR_4 PF07721.14 CDS28438.1 - 0.12 13.0 1.6 69 4.5 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS28438.1 - 0.14 12.4 2.7 64 4.1 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28438.1 - 0.73 10.2 7.5 18 5.7 0.2 4.9 4 2 3 7 7 7 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 CDS28439.1 - 2.3e-70 236.8 0.0 3e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS28439.1 - 1.2e-46 159.2 0.0 1.7e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 CDS28439.1 - 7.6e-16 57.5 0.4 3.2e-15 55.5 0.3 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDS28439.1 - 1.8e-14 53.3 0.3 8.7e-14 51.1 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CDS28439.1 - 1.3e-09 37.6 0.2 3.9e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH2 PF00017.24 CDS28439.1 - 2.9e-07 30.5 0.0 7.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Kinase-like PF14531.6 CDS28439.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CDS28439.1 - 0.011 15.4 0.1 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SH3_16 PF18348.1 CDS28439.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Tektin PF03148.14 CDS28440.1 - 2e-95 319.8 32.7 2.4e-95 319.5 32.7 1.0 1 0 0 1 1 1 1 Tektin family T3SS_basalb_I PF17001.5 CDS28440.1 - 0.14 12.8 7.0 0.13 12.8 1.9 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Spc29 PF17082.5 CDS28440.1 - 0.74 9.6 0.0 0.74 9.6 0.0 3.6 2 2 0 2 2 2 0 Spindle Pole Component 29 GPS2_interact PF15784.5 CDS28440.1 - 1.1 9.7 18.0 0.046 14.2 2.9 3.2 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF5082 PF16888.5 CDS28440.1 - 7.1 6.9 19.3 3.3 8.0 10.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) WD40 PF00400.32 CDS28441.1 - 2.2e-09 37.8 15.4 0.011 16.5 0.2 8.2 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28441.1 - 0.002 18.4 0.0 0.17 12.2 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Sad1_UNC PF07738.13 CDS28442.1 - 4e-36 123.9 0.0 9.5e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SKA2 PF16740.5 CDS28442.1 - 0.0041 16.9 11.4 0.37 10.6 0.1 4.5 3 2 2 5 5 5 2 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 CDS28442.1 - 0.019 15.0 12.5 0.28 11.2 1.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CDS28442.1 - 0.025 12.6 13.9 0.055 11.4 7.9 2.3 1 1 1 2 2 2 0 Prominin Trans_reg_C PF00486.28 CDS28442.1 - 0.026 14.6 0.2 0.14 12.3 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Baculo_PEP_C PF04513.12 CDS28442.1 - 0.071 13.2 14.3 0.71 9.9 4.9 3.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3131 PF11329.8 CDS28442.1 - 0.072 12.1 0.4 0.11 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) BLOC1_2 PF10046.9 CDS28442.1 - 0.081 13.2 13.4 0.17 12.2 0.2 3.8 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 CDS28442.1 - 0.086 13.3 10.6 1.4 9.4 0.2 3.3 2 1 1 3 3 3 0 Spectrin repeat KLRAQ PF10205.9 CDS28442.1 - 0.12 12.6 16.1 0.21 11.8 0.4 3.8 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.10 CDS28442.1 - 0.15 12.2 18.4 4.1 7.6 0.8 4.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2959 PF11172.8 CDS28442.1 - 0.21 11.7 14.4 0.055 13.6 6.0 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2959) TPR_MLP1_2 PF07926.12 CDS28442.1 - 0.22 11.6 24.1 4.3 7.4 0.2 3.6 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 CDS28442.1 - 0.23 12.0 16.3 0.14 12.6 0.5 3.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 Tup_N PF08581.10 CDS28442.1 - 0.34 11.3 12.1 0.35 11.2 2.6 3.9 3 1 1 4 4 4 0 Tup N-terminal Spore_III_AB PF09548.10 CDS28442.1 - 0.57 10.3 4.9 1.5 8.9 4.9 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF5082 PF16888.5 CDS28442.1 - 0.75 10.1 17.5 0.29 11.4 7.4 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Fzo_mitofusin PF04799.13 CDS28442.1 - 0.84 9.2 16.1 0.59 9.7 0.4 3.5 1 1 2 3 3 3 0 fzo-like conserved region Phage_GP20 PF06810.11 CDS28442.1 - 0.86 9.4 18.0 2.4 7.9 6.3 3.6 2 2 1 3 3 3 0 Phage minor structural protein GP20 UPF0242 PF06785.11 CDS28442.1 - 1.6 8.8 23.8 0.091 12.9 0.4 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 CDS28442.1 - 4.2 7.4 16.4 19 5.3 0.0 4.4 4 1 0 4 4 4 0 Prefoldin subunit COG2 PF06148.11 CDS28442.1 - 4.8 7.3 18.7 22 5.1 4.2 5.2 1 1 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 GCN5L1 PF06320.13 CDS28442.1 - 5.2 7.2 9.4 1.6 8.9 1.4 3.1 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Nsp1_C PF05064.13 CDS28442.1 - 5.2 6.9 15.2 3.5 7.5 4.1 4.2 3 2 2 5 5 5 0 Nsp1-like C-terminal region Alpha-E PF04168.12 CDS28442.1 - 5.7 6.6 11.6 0.33 10.7 0.4 2.9 2 1 1 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. LPP PF04728.13 CDS28442.1 - 6.3 7.3 17.9 21 5.6 6.2 5.2 4 1 0 4 4 4 0 Lipoprotein leucine-zipper UPF0184 PF03670.13 CDS28442.1 - 7.5 7.0 8.3 7.8 7.0 0.2 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) bZIP_1 PF00170.21 CDS28442.1 - 9.7 6.4 15.8 24 5.1 0.1 4.7 5 0 0 5 5 4 0 bZIP transcription factor MFS_1 PF07690.16 CDS28443.1 - 2.7e-14 52.9 21.4 1.6e-08 33.9 2.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS28443.1 - 5.7 5.7 23.6 0.015 14.2 3.7 3.4 2 2 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 CDS28444.1 - 4.1e-27 95.0 25.2 1.5e-25 89.9 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Voltage_CLC PF00654.20 CDS28445.1 - 3.7e-98 329.0 25.9 3.8e-98 329.0 24.1 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CDS28445.1 - 1.8e-17 63.5 0.1 2e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain RAWUL PF16207.5 CDS28446.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ribosomal_S7e PF01251.18 CDS28447.1 - 1.5e-68 230.2 0.4 1.7e-68 230.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PVL_ORF50 PF07768.11 CDS28447.1 - 0.095 13.0 0.2 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 PVL ORF-50-like family MFS_1 PF07690.16 CDS28448.1 - 3.6e-30 105.1 38.4 3.6e-30 105.1 38.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDS28448.1 - 1.5e-11 43.3 24.3 0.00011 20.6 1.5 4.1 2 1 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CDS28448.1 - 0.0029 16.2 28.3 0.007 15.0 1.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein TMPIT PF07851.13 CDS28449.1 - 4.4e-114 381.1 15.7 5.5e-114 380.8 15.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein PI3K_P85_iSH2 PF16454.5 CDS28449.1 - 0.024 14.2 3.3 0.036 13.7 3.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lge1 PF11488.8 CDS28449.1 - 0.32 11.2 2.0 0.98 9.6 1.6 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 HVSL PF09749.9 CDS28451.1 - 6e-33 114.3 0.0 1.1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-RING_UBOX PF13445.6 CDS28451.1 - 8e-08 32.2 2.5 8e-08 32.2 2.5 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS28451.1 - 1.1e-07 31.9 1.2 1.1e-07 31.9 1.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDS28451.1 - 3.1e-07 30.1 2.3 1.1e-06 28.4 2.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS28451.1 - 2.2e-06 27.4 0.8 2.2e-06 27.4 0.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS28451.1 - 6.8e-06 25.9 2.8 1e-05 25.4 0.5 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDS28451.1 - 8.7e-05 22.8 4.3 8.7e-05 22.8 4.3 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS28451.1 - 0.54 10.2 11.5 0.038 13.9 4.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS28451.1 - 0.78 10.1 6.1 0.19 12.0 1.8 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDS28451.1 - 5.8 6.9 19.8 0.027 14.3 7.5 3.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 Fer4 PF00037.27 CDS28452.1 - 2.9e-14 52.2 17.0 1.4e-08 34.2 4.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDS28452.1 - 4.7e-13 49.5 10.0 8.4e-13 48.7 10.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDS28452.1 - 4.6e-10 40.3 6.2 0.00017 22.5 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 CDS28452.1 - 1.3e-09 38.0 20.6 7.8e-07 29.1 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDS28452.1 - 2.9e-09 37.0 10.0 2.9e-09 37.0 10.0 1.6 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CDS28452.1 - 3.4e-09 36.7 31.2 7.9e-06 25.9 12.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDS28452.1 - 3.6e-07 30.0 17.4 0.00034 20.5 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CDS28452.1 - 1.2e-06 28.8 18.9 0.00022 21.6 11.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 CDS28452.1 - 7.9e-06 26.0 11.3 0.00031 21.0 2.0 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDS28452.1 - 0.00024 21.0 17.0 0.0061 16.6 2.2 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDS28452.1 - 0.00031 21.2 10.8 0.026 15.1 11.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CDS28452.1 - 0.008 16.4 6.2 0.14 12.4 0.4 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CDS28452.1 - 0.019 15.2 8.1 0.58 10.4 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDS28452.1 - 0.02 15.5 14.4 0.65 10.6 4.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CDS28452.1 - 0.07 14.1 3.8 0.07 14.1 3.8 2.6 3 0 0 3 3 2 0 4Fe-4S binding domain ETF_QO PF05187.13 CDS28452.1 - 0.26 11.4 5.8 1.3 9.2 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CDS28452.1 - 2.9 8.8 14.8 2.8 8.8 1.8 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain HAT PF02184.16 CDS28453.1 - 1.5e-29 101.7 75.1 4.4e-14 52.1 1.3 14.0 14 2 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CDS28453.1 - 3.3e-20 71.0 32.3 0.13 13.1 0.1 11.9 5 2 7 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28453.1 - 4.4e-16 59.1 3.4 0.0053 17.2 0.0 7.9 3 2 4 9 9 9 3 Tetratricopeptide repeat Suf PF05843.14 CDS28453.1 - 2e-11 44.5 30.2 0.00017 21.7 4.0 5.8 2 1 3 6 6 5 4 Suppressor of forked protein (Suf) TPR_16 PF13432.6 CDS28453.1 - 7.5e-08 32.9 13.7 0.38 11.4 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28453.1 - 8.3e-08 32.1 1.3 0.17 12.3 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDS28453.1 - 3e-05 24.0 25.8 0.084 12.9 3.3 6.7 6 1 0 6 6 5 2 Mad3/BUB1 homology region 1 Kinase-PPPase PF03618.14 CDS28453.1 - 0.007 16.2 1.0 0.21 11.3 0.3 3.1 2 1 0 2 2 2 1 Kinase/pyrophosphorylase TPR_2 PF07719.17 CDS28453.1 - 0.0076 16.3 34.8 6.4 7.1 0.1 10.3 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28453.1 - 0.014 15.6 10.3 13 6.0 0.1 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 CDS28453.1 - 0.014 13.6 0.0 0.025 12.8 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus BSD PF03909.17 CDS28453.1 - 0.019 15.0 2.2 1.1 9.3 0.3 2.9 2 0 0 2 2 2 0 BSD domain TPR_8 PF13181.6 CDS28453.1 - 0.026 14.7 8.2 8.6 6.9 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28453.1 - 0.067 13.5 17.1 3.9 7.8 0.1 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat QIL1 PF15884.5 CDS28453.1 - 0.1 13.2 0.2 1.7 9.3 0.0 2.9 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 TPR_6 PF13174.6 CDS28453.1 - 0.13 13.0 23.0 10 7.0 0.1 9.3 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28453.1 - 1.3 9.2 9.5 9.6 6.5 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS28453.1 - 4.7 7.4 7.1 4.9 7.3 0.0 4.6 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat ThiF PF00899.21 CDS28454.1 - 1.7e-17 63.6 0.0 3.6e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 ThiF family WH1 PF00568.23 CDS28455.1 - 1.4e-12 47.5 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CDS28455.1 - 0.03 14.7 0.0 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain COesterase PF00135.28 CDS28457.1 - 5.1e-77 259.9 0.0 8.5e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS28457.1 - 9.9e-06 25.5 0.1 2.4e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDS28457.1 - 0.00037 21.2 0.2 0.00097 19.8 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDS28457.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Mcm10 PF09332.11 CDS28458.1 - 2e-51 175.5 6.7 2e-51 175.5 6.7 3.2 3 1 1 4 4 4 1 Mcm10 replication factor zf-primase PF09329.11 CDS28458.1 - 3e-15 55.8 1.5 3e-15 55.8 1.5 2.0 2 0 0 2 2 2 1 Primase zinc finger PSP PF04046.16 CDS28458.1 - 7.1e-15 54.6 0.2 1.3e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 PSP TF_Zn_Ribbon PF08271.12 CDS28458.1 - 0.29 10.7 2.1 0.58 9.7 1.2 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding MBF1 PF08523.10 CDS28459.1 - 8.6e-16 58.2 0.7 1.8e-15 57.1 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CDS28459.1 - 4.6e-13 49.0 0.6 8.2e-13 48.2 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CDS28459.1 - 1.2e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CDS28459.1 - 0.00016 21.6 0.5 0.0009 19.2 0.4 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CDS28459.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_24 PF13412.6 CDS28459.1 - 0.15 11.7 1.2 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF5383 PF17355.2 CDS28460.1 - 0.12 12.7 1.6 0.37 11.2 1.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5383) GAS PF13851.6 CDS28461.1 - 0.17 11.2 5.0 0.24 10.7 1.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_transf_22 PF03901.17 CDS28462.1 - 3.3e-92 309.9 26.3 4.1e-92 309.6 26.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TGT PF01702.18 CDS28463.1 - 1.2e-124 416.0 0.0 1.4e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-C2H2 PF00096.26 CDS28464.1 - 2.8e-13 49.5 45.6 2.8e-06 27.5 4.5 7.7 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28464.1 - 1.9e-12 46.9 46.9 0.00045 20.8 4.1 7.7 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS28464.1 - 3.5e-11 43.0 38.8 0.00016 22.0 3.6 8.0 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS28464.1 - 3.4e-07 30.4 32.0 0.0054 17.0 2.0 7.2 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS28464.1 - 0.00055 20.2 33.4 0.056 13.8 1.2 7.2 5 2 2 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDS28464.1 - 0.015 15.7 4.2 0.015 15.7 4.2 6.8 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DUF4648 PF15505.6 CDS28464.1 - 0.039 14.8 0.4 7.9 7.4 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) GAGA PF09237.11 CDS28464.1 - 0.4 10.5 9.1 0.65 9.9 1.9 3.6 3 0 0 3 3 3 0 GAGA factor BolA PF01722.18 CDS28464.1 - 0.4 11.0 3.7 0.21 11.9 0.7 2.1 2 0 0 2 2 1 0 BolA-like protein zf-H2C2_5 PF13909.6 CDS28464.1 - 0.57 10.0 17.8 0.53 10.1 0.5 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDS28464.1 - 0.6 10.5 26.0 20 5.6 0.3 5.6 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 CDS28464.1 - 1.1 9.8 27.5 1.2 9.6 0.1 6.7 5 1 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 CDS28464.1 - 1.1 9.4 27.3 6.3 7.0 5.3 6.2 5 1 1 6 6 6 0 Zinc ribbon domain Spt4 PF06093.13 CDS28464.1 - 2.2 8.4 9.6 0.058 13.5 0.6 3.2 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger FOXP-CC PF16159.5 CDS28464.1 - 7.8 7.2 8.8 0.63 10.7 0.4 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain Mito_carr PF00153.27 CDS28465.1 - 5.1e-52 173.8 1.9 2.2e-20 72.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CDS28466.1 - 2.5e-16 59.8 0.7 9.5e-12 45.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS28466.1 - 5.1e-14 50.7 0.1 5.1e-07 28.8 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CDS28466.1 - 1.3e-12 46.6 0.3 0.00023 20.8 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDS28466.1 - 1.7e-11 43.1 0.1 3e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDS28466.1 - 3e-05 23.8 0.1 0.019 14.8 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS28466.1 - 0.00065 20.0 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CDS28466.1 - 0.0039 17.3 0.8 0.079 13.2 0.9 2.4 1 1 1 2 2 2 2 Dockerin type I domain adh_short PF00106.25 CDS28467.1 - 1.4e-28 99.7 3.6 2.8e-17 62.8 0.0 3.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS28467.1 - 3.2e-17 62.9 4.3 2.6e-11 43.5 0.0 3.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS28467.1 - 2.5e-05 24.3 0.2 7e-05 22.8 0.2 1.7 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CDS28467.1 - 2.6e-05 23.6 0.3 6.6e-05 22.3 0.3 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CDS28467.1 - 0.00053 19.5 0.1 0.0009 18.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDS28467.1 - 0.043 13.7 0.2 0.089 12.7 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_transf_4 PF13439.6 CDS28467.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 adh_short PF00106.25 CDS28468.1 - 0.017 14.6 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RasGEF PF00617.19 CDS28469.1 - 1.6e-39 135.9 0.3 4.2e-39 134.6 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain SURF1 PF02104.15 CDS28471.1 - 1.4e-08 35.2 0.0 0.0024 18.2 0.0 2.1 1 1 1 2 2 2 2 SURF1 family HTH_Mga PF08280.11 CDS28471.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain PRP38 PF03371.15 CDS28472.1 - 1.3e-58 197.7 0.9 1.7e-58 197.3 0.9 1.1 1 0 0 1 1 1 1 PRP38 family Claudin_2 PF13903.6 CDS28473.1 - 2.3e-22 79.7 1.9 3.9e-22 78.9 1.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CDS28473.1 - 2.7e-07 30.6 8.2 8.2e-05 22.5 8.2 2.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SLAC1 PF03595.17 CDS28473.1 - 0.0049 16.2 1.2 0.0074 15.6 0.2 1.6 1 1 0 1 1 1 1 Voltage-dependent anion channel PAF-AH_p_II PF03403.13 CDS28473.1 - 0.029 12.9 0.1 0.061 11.8 0.1 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1772 PF08592.11 CDS28473.1 - 0.069 13.5 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Vut_1 PF02592.15 CDS28473.1 - 0.092 13.1 0.6 0.18 12.1 0.6 1.4 1 0 0 1 1 1 0 Putative vitamin uptake transporter RhoGAP PF00620.27 CDS28474.1 - 1.6e-38 131.9 0.0 2.8e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 CDS28474.1 - 9.9e-34 116.5 0.7 1.8e-33 115.6 0.2 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDS28474.1 - 7.1e-09 35.6 0.5 1.8e-08 34.3 0.5 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain dsDNA_bind PF01984.20 CDS28475.1 - 3.7e-27 94.8 10.3 4.5e-27 94.5 10.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain NDUF_B4 PF07225.12 CDS28475.1 - 0.01 15.7 0.7 0.012 15.5 0.7 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF1759 PF03564.15 CDS28475.1 - 0.028 14.4 0.2 0.084 12.8 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) ACP_PD PF04336.12 CDS28475.1 - 0.06 13.8 0.6 0.06 13.8 0.6 1.9 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase zf-C2H2 PF00096.26 CDS28476.1 - 2.6e-15 55.9 17.8 1.9e-05 24.9 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS28476.1 - 1.7e-13 50.3 20.0 2.9e-07 30.6 1.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS28476.1 - 8.8e-08 32.4 17.5 0.0068 17.2 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS28476.1 - 0.044 14.1 3.7 2.2 8.7 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CDS28476.1 - 0.14 12.5 2.6 0.69 10.2 2.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CDS28476.1 - 0.27 11.6 3.5 1.1 9.7 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RabGAP-TBC PF00566.18 CDS28478.1 - 5.5e-45 153.6 0.1 6.3e-44 150.2 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mito_fiss_reg PF05308.11 CDS28478.1 - 1.4 8.9 7.9 0.39 10.8 4.5 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator VPS9 PF02204.18 CDS28479.1 - 6.3e-20 71.3 0.0 1.3e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CDS28479.1 - 3e-15 56.3 0.6 1.3e-13 51.1 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) zf-A20 PF01754.16 CDS28479.1 - 1.6e-10 40.7 9.7 3e-10 39.8 9.7 1.5 1 0 0 1 1 1 1 A20-like zinc finger zf-RanBP PF00641.18 CDS28479.1 - 0.14 11.5 4.2 0.3 10.5 4.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others WD40 PF00400.32 CDS28481.2 - 0.0068 17.2 0.1 1.5 9.8 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat RhoGEF PF00621.20 CDS28481.2 - 0.061 13.6 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 RhoGEF domain BUD22 PF09073.10 CDS28483.1 - 0.22 10.8 46.7 0.27 10.5 46.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CDS28483.1 - 1 7.5 39.0 1.4 7.0 39.0 1.1 1 0 0 1 1 1 0 Nop14-like family Asp-B-Hydro_N PF05279.11 CDS28483.1 - 1.4 8.9 29.6 1.8 8.6 29.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SURF2 PF05477.11 CDS28483.1 - 3.1 7.4 32.4 3.7 7.2 32.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Neur_chan_memb PF02932.16 CDS28483.1 - 6.1 6.8 15.1 8.6 6.3 15.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5423 PF17461.2 CDS28485.1 - 0.025 13.4 0.8 0.026 13.4 0.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) FumaraseC_C PF10415.9 CDS28485.1 - 0.044 14.2 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Fumarase C C-terminus YqzE PF14038.6 CDS28485.1 - 0.086 12.9 2.5 0.14 12.1 2.5 1.4 1 0 0 1 1 1 0 YqzE-like protein Ion_trans_2 PF07885.16 CDS28486.1 - 1.8e-33 114.4 15.4 1.5e-19 69.7 1.5 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDS28486.1 - 8.4e-05 21.9 5.5 0.0063 15.8 0.8 2.3 2 0 0 2 2 2 2 Ion transport protein Shisa PF13908.6 CDS28486.1 - 0.68 10.1 3.3 1.7 8.9 0.2 2.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator U3_assoc_6 PF08640.11 CDS28487.2 - 3.8e-18 65.3 5.4 3.8e-18 65.3 5.4 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 PVL_ORF50 PF07768.11 CDS28487.2 - 0.17 12.2 6.9 0.18 12.1 1.4 2.9 2 0 0 2 2 2 0 PVL ORF-50-like family TPR_14 PF13428.6 CDS28487.2 - 3.4 8.7 5.4 57 4.9 0.0 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat Nuc_sug_transp PF04142.15 CDS28488.1 - 9.6e-100 333.8 23.0 1.2e-99 333.5 23.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CDS28488.1 - 3.6e-08 33.6 33.1 2.9e-05 24.3 7.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDS28488.1 - 3.5e-05 23.2 19.9 5.7e-05 22.5 19.9 1.5 1 1 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 CDS28488.1 - 4.8 7.3 15.3 4.2 7.4 4.5 3.0 3 1 0 3 3 3 0 Putative transmembrane family 234 DNase_II PF03265.15 CDS28489.1 - 8.7e-76 255.3 0.5 9.7e-76 255.1 0.5 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Laminin_II PF06009.12 CDS28490.1 - 0.0065 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Laminin Domain II Retrotrans_gag PF03732.17 CDS28490.1 - 0.0074 16.5 0.3 0.02 15.1 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein MbeD_MobD PF04899.12 CDS28490.1 - 0.042 14.0 0.2 0.097 12.8 0.1 1.8 1 1 0 1 1 1 0 MbeD/MobD like Hydantoinase_B PF02538.14 CDS28490.1 - 0.13 10.7 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase LPP PF04728.13 CDS28490.1 - 0.27 11.7 1.2 0.48 10.9 0.3 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper rve_3 PF13683.6 CDS28491.1 - 0.0001 22.0 0.1 0.00072 19.3 0.0 2.1 1 1 1 2 2 2 1 Integrase core domain rve PF00665.26 CDS28491.1 - 0.00034 20.8 0.0 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1794 PF08768.11 CDS28492.1 - 4.3e-28 98.1 0.0 4.9e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) YIF1 PF03878.15 CDS28493.1 - 2.1e-78 263.2 5.7 2.5e-78 262.9 5.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CDS28493.1 - 0.0088 15.8 19.3 0.017 14.9 18.3 1.8 1 1 0 1 1 1 1 Yip1 domain Ion_trans PF00520.31 CDS28494.1 - 1.4e-06 27.7 0.4 1.4e-06 27.7 0.4 1.7 2 0 0 2 2 2 1 Ion transport protein DUF3853 PF12964.7 CDS28494.1 - 0.034 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_28 PF13518.6 CDS28494.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Zincin_1 PF06262.11 CDS28494.1 - 0.11 12.6 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Zincin-like metallopeptidase FeoC PF09012.10 CDS28494.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Myc_target_1 PF15179.6 CDS28494.1 - 0.37 10.7 7.1 0.19 11.6 4.1 2.1 2 0 0 2 2 2 0 Myc target protein 1 Utp12 PF04003.12 CDS28495.1 - 0.00032 21.0 0.3 0.0012 19.2 0.3 1.9 1 1 0 1 1 1 1 Dip2/Utp12 Family SPT6_acidic PF14632.6 CDS28495.1 - 0.014 16.0 1.5 0.028 15.0 1.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 R3H-assoc PF13902.6 CDS28495.1 - 0.16 12.4 2.2 0.2 12.1 1.3 1.7 2 0 0 2 2 2 0 R3H-associated N-terminal domain Striatin PF08232.12 CDS28496.2 - 0.01 16.5 4.5 0.015 15.9 4.5 1.3 1 0 0 1 1 1 0 Striatin family SlyX PF04102.12 CDS28496.2 - 9.4 6.9 10.2 1.3 9.7 0.7 2.9 3 0 0 3 3 3 0 SlyX DRIM PF07539.12 CDS28497.2 - 1.7e-83 281.0 5.0 1.7e-83 281.0 5.0 4.5 8 0 0 8 8 8 1 Down-regulated in metastasis dsDNA_bind PF01984.20 CDS28497.2 - 0.11 12.8 1.8 0.54 10.6 1.8 2.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain G-alpha PF00503.20 CDS28498.1 - 1.1e-124 416.3 6.6 1.4e-124 415.9 6.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS28498.1 - 3.8e-17 62.3 2.7 3.7e-13 49.3 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS28498.1 - 1.7e-05 24.3 5.5 0.00093 18.6 2.3 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDS28498.1 - 2.7e-05 24.4 0.8 0.085 13.1 0.2 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS28498.1 - 0.0044 16.6 2.7 0.18 11.4 1.1 2.4 2 0 0 2 2 2 2 Ras family TniB PF05621.11 CDS28498.1 - 0.0069 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 CDS28498.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP12 PF07542.11 CDS28499.1 - 9.6e-31 106.5 0.0 1.7e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Curto_V2 PF07325.11 CDS28499.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein UPRTase PF14681.6 CDS28500.2 - 6.6e-99 329.5 0.0 6.4e-66 221.7 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.18 CDS28500.2 - 6.4e-38 130.5 0.0 9.8e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RL10P_insert PF17777.1 CDS28500.2 - 2.7e-05 24.1 0.0 0.21 11.6 0.0 2.7 2 0 0 2 2 2 2 Insertion domain in 60S ribosomal protein L10P DUF3932 PF13068.6 CDS28502.1 - 0.081 13.2 1.6 0.081 13.2 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3932) DUF3932 PF13068.6 CDS28504.2 - 0.0077 16.5 1.4 0.0077 16.5 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3932) zf-H2C2_2 PF13465.6 CDS28506.2 - 2.2e-09 37.3 1.4 1.5e-05 25.2 0.2 3.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS28506.2 - 3.5e-06 27.1 12.1 0.0001 22.6 4.2 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28506.2 - 0.016 16.0 3.2 0.016 16.0 3.2 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS28508.2 - 0.012 16.0 13.4 2.8 8.5 1.4 5.5 4 0 0 4 4 4 0 Zinc-finger double domain Med7 PF05983.11 CDS28508.2 - 0.018 15.1 5.6 0.018 15.1 5.6 2.1 2 0 0 2 2 2 0 MED7 protein DUF3932 PF13068.6 CDS28509.1 - 0.081 13.2 1.6 0.081 13.2 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3932) ATP12 PF07542.11 CDS28512.2 - 2e-30 105.5 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Curto_V2 PF07325.11 CDS28512.2 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Curtovirus V2 protein G-alpha PF00503.20 CDS28513.1 - 1.1e-124 416.3 6.6 1.4e-124 415.9 6.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS28513.1 - 3.8e-17 62.3 2.7 3.7e-13 49.3 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS28513.1 - 1.7e-05 24.3 5.5 0.00093 18.6 2.3 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDS28513.1 - 2.7e-05 24.4 0.8 0.085 13.1 0.2 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS28513.1 - 0.0044 16.6 2.7 0.18 11.4 1.1 2.4 2 0 0 2 2 2 2 Ras family TniB PF05621.11 CDS28513.1 - 0.0069 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 CDS28513.1 - 0.07 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DRIM PF07539.12 CDS28514.1 - 1.5e-87 294.4 4.4 1.5e-87 294.4 4.4 3.5 5 0 0 5 5 5 1 Down-regulated in metastasis dsDNA_bind PF01984.20 CDS28514.1 - 0.083 13.2 1.8 0.37 11.1 1.8 2.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Striatin PF08232.12 CDS28515.2 - 0.018 15.6 4.5 0.033 14.8 4.5 1.4 1 0 0 1 1 1 0 Striatin family SlyX PF04102.12 CDS28515.2 - 3.6 8.3 7.5 2.2 9.0 0.7 2.9 3 0 0 3 3 3 0 SlyX IMD PF08397.11 CDS28516.1 - 6.5e-31 107.4 3.4 1.1e-30 106.7 3.4 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain Sun2_CC2 PF18580.1 CDS28516.1 - 0.083 13.1 0.3 0.25 11.6 0.3 1.8 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 SVIP PF15811.5 CDS28516.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.7 4 0 0 4 4 4 0 Small VCP/p97-interacting protein DegS PF05384.11 CDS28516.1 - 3.9 6.9 7.0 2.4 7.6 0.0 2.9 3 1 0 3 3 3 0 Sensor protein DegS Ribosomal_S28e PF01200.18 CDS28517.1 - 1.5e-28 98.6 0.1 1.6e-28 98.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Proteasome PF00227.26 CDS28520.1 - 2.2e-31 108.8 0.1 3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Taxilin PF09728.9 CDS28521.1 - 2.7e-55 187.7 50.4 4.1e-54 183.9 42.5 2.3 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Snapin_Pallidin PF14712.6 CDS28521.1 - 0.36 11.3 32.8 0.83 10.1 3.6 4.8 3 2 2 5 5 5 0 Snapin/Pallidin LLC1 PF14945.6 CDS28521.1 - 4.7 7.8 10.5 0.28 11.8 1.5 3.0 1 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF812 PF05667.11 CDS28521.1 - 8.4 5.1 44.8 1.1e+02 1.5 44.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) RRM_1 PF00076.22 CDS28522.1 - 5.5e-36 122.2 2.8 3e-18 65.4 0.2 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28522.1 - 2.1e-15 56.6 0.4 1.6e-06 28.1 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS28522.1 - 1.9e-07 31.0 0.2 0.00063 19.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS28522.1 - 0.0002 21.3 0.7 0.04 14.0 0.1 2.4 1 1 1 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 CDS28522.1 - 0.014 15.6 5.6 1.9 8.7 0.0 3.3 2 1 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Steroid_dh PF02544.16 CDS28523.1 - 2.2e-31 108.9 3.8 2.2e-31 108.9 3.8 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CDS28523.1 - 0.023 15.1 0.3 0.023 15.1 0.3 2.3 2 0 0 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.23 CDS28523.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DUF1295 PF06966.12 CDS28523.1 - 0.18 11.3 4.8 0.03 13.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Kri1_C PF12936.7 CDS28523.1 - 0.19 11.9 0.2 0.4 10.9 0.0 1.5 2 0 0 2 2 2 0 KRI1-like family C-terminal DUF483 PF04467.12 CDS28524.1 - 0.074 13.1 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF483) HOOK PF05622.12 CDS28526.1 - 6.1e-76 256.1 47.1 9.1e-56 189.4 34.7 2.2 1 1 0 2 2 2 2 HOOK protein Pyridoxal_deC PF00282.19 CDS28526.1 - 0.037 12.7 0.5 3 6.5 0.1 2.2 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain ComP_DUS PF16732.5 CDS28526.1 - 2.1 9.3 5.8 1.9 9.4 0.3 3.1 2 1 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor RT_RNaseH_2 PF17919.1 CDS28529.2 - 7.3e-29 99.8 0.6 3.7e-28 97.5 0.2 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS28529.2 - 7e-28 97.7 0.0 1.2e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDS28529.2 - 2.2e-27 95.4 0.1 5.9e-27 94.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS28529.2 - 5.4e-23 81.5 0.0 1.8e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS28529.2 - 4.9e-15 55.4 0.8 1.2e-14 54.1 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CDS28529.2 - 0.00054 19.7 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDS28529.2 - 0.0047 17.2 0.0 0.071 13.3 0.0 2.8 4 0 0 4 4 4 1 DDE domain zf-H2C2 PF09337.10 CDS28529.2 - 0.044 14.0 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Peptidase_A17 PF05380.13 CDS28529.2 - 0.084 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Pao retrotransposon peptidase Mgr1 PF08602.10 CDS28529.2 - 0.18 10.6 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DEAD PF00270.29 CDS28531.1 - 2.8e-47 160.8 0.4 9.7e-47 159.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS28531.1 - 4.1e-27 94.7 0.1 4.2e-25 88.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDS28531.1 - 1.1e-10 41.6 0.1 2.9e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDS28531.1 - 3.7e-08 33.5 0.0 6.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KcnmB2_inactiv PF09303.10 CDS28531.1 - 0.015 15.1 0.3 0.035 13.9 0.3 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain AAA_22 PF13401.6 CDS28531.1 - 0.02 15.2 0.9 0.068 13.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDS28531.1 - 0.031 13.5 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDS28531.1 - 0.1 12.3 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 CDS28532.1 - 2.2e-11 43.7 14.8 4.7e-11 42.6 14.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDS28532.1 - 1.2e-05 25.3 14.5 4.4e-05 23.5 13.7 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS28532.1 - 0.016 15.7 7.7 0.016 15.7 7.7 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.15 CDS28532.1 - 0.056 13.2 2.4 0.17 11.7 2.4 1.8 1 0 0 1 1 1 0 Septum formation initiator CENP-F_leu_zip PF10473.9 CDS28532.1 - 0.17 11.9 7.1 0.38 10.8 7.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 CDS28533.2 - 2.1e-21 76.8 39.3 7.8e-17 61.8 36.6 2.2 1 1 0 1 1 1 1 Intermediate filament protein CEP209_CC5 PF16574.5 CDS28533.2 - 0.0023 18.1 0.9 0.0023 18.1 0.9 3.2 2 1 1 3 3 3 1 Coiled-coil region of centrosome protein CE290 LTD PF00932.19 CDS28533.2 - 0.0048 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Lamin Tail Domain V_ATPase_I PF01496.19 CDS28533.2 - 0.19 9.6 16.6 0.27 9.1 16.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T3SSipB PF16535.5 CDS28533.2 - 0.44 11.0 8.3 1.2 9.6 7.5 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB Fez1 PF06818.15 CDS28533.2 - 0.82 10.1 32.3 0.03 14.8 1.8 2.7 2 1 1 3 3 3 0 Fez1 CCM2_C PF16545.5 CDS28533.2 - 5.3 7.6 7.2 6.4 7.4 0.5 2.7 2 0 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Prp19 PF08606.11 CDS28534.1 - 2.7e-32 110.5 1.3 6.7e-32 109.3 1.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CDS28534.1 - 2.6e-31 107.1 6.8 1.6e-05 25.6 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28534.1 - 1.2e-14 54.3 0.2 0.056 13.7 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 CDS28534.1 - 1e-07 32.0 0.0 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 CDS28534.1 - 1.7e-05 23.9 0.1 0.0075 15.3 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 CDS28534.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.8 CDS28534.1 - 0.00021 20.1 0.1 0.16 10.6 0.0 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CDS28534.1 - 0.018 14.4 0.1 0.22 10.8 0.1 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CDS28534.1 - 0.03 13.6 0.0 5.9 6.1 0.0 3.0 2 1 0 3 3 3 0 WD40-like domain Spc7 PF08317.11 CDS28535.1 - 0.043 12.7 6.1 0.033 13.1 0.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 CDS28535.1 - 0.4 11.0 4.2 0.88 9.9 0.4 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) CRIC_ras_sig PF10534.9 CDS28535.1 - 0.79 9.9 4.5 0.83 9.9 0.0 3.3 5 0 0 5 5 5 0 Connector enhancer of kinase suppressor of ras BLOC1_2 PF10046.9 CDS28535.1 - 5.1 7.5 7.1 10 6.5 0.7 3.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRM_1 PF00076.22 CDS28536.1 - 3.5e-28 97.2 0.0 9.4e-10 38.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CDS28536.1 - 1.8e-25 89.6 0.1 5.1e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 SPOC domain RRM_5 PF13893.6 CDS28536.1 - 1.8e-06 27.6 0.0 0.0095 15.5 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS28536.1 - 0.0013 18.5 0.0 0.017 14.9 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF1866 PF08952.11 CDS28536.1 - 0.0032 17.3 0.0 0.078 12.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) DNA_pol3_delta2 PF13177.6 CDS28537.2 - 7.9e-15 55.0 0.0 7.1e-09 35.7 0.0 3.1 2 1 0 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CDS28537.2 - 6.3e-14 52.5 0.0 3.6e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CDS28537.2 - 2.2e-10 40.8 0.3 7.7e-10 39.1 0.1 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CDS28537.2 - 1.8e-07 31.3 0.0 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CDS28537.2 - 2.4e-06 28.1 0.1 2.4e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDS28537.2 - 4.8e-05 23.6 0.0 0.0018 18.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDS28537.2 - 0.00012 22.0 0.0 0.00075 19.4 0.0 2.2 2 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 CDS28537.2 - 0.00012 21.5 0.0 0.00088 18.7 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CDS28537.2 - 0.00035 19.8 0.0 0.00072 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDS28537.2 - 0.00084 19.1 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDS28537.2 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CDS28537.2 - 0.003 17.9 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 CDS28537.2 - 0.0034 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS28537.2 - 0.0072 16.9 0.0 0.031 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 CDS28537.2 - 0.0088 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDS28537.2 - 0.009 16.0 0.0 0.035 14.1 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CDS28537.2 - 0.011 15.5 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 CDS28537.2 - 0.013 15.5 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDS28537.2 - 0.017 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS28537.2 - 0.018 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CDS28537.2 - 0.026 14.0 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 CDS28537.2 - 0.035 14.5 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 CDS28537.2 - 0.041 13.5 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDS28537.2 - 0.051 14.1 0.1 0.092 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDS28537.2 - 0.063 13.6 0.0 0.29 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDS28537.2 - 0.075 12.9 0.0 0.23 11.3 0.0 1.7 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CDS28537.2 - 0.089 12.6 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_33 PF13671.6 CDS28537.2 - 0.15 12.2 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CDS28537.2 - 0.17 11.6 0.0 3.5 7.4 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase LPD26 PF18842.1 CDS28537.2 - 1.9 8.5 4.6 54 3.9 0.2 3.9 5 0 0 5 5 5 0 Large polyvalent protein associated domain 26 FAR1 PF03101.15 CDS28538.2 - 2.2e-05 25.0 0.3 5.5e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain FAA_hydro_N_2 PF18288.1 CDS28538.2 - 0.17 12.3 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 GDPD PF03009.17 CDS28539.1 - 5.7e-21 75.4 0.0 2.7e-19 69.9 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ATP-synt PF00231.19 CDS28540.1 - 2.3e-77 260.5 1.9 2.5e-77 260.3 1.9 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_L29 PF00831.23 CDS28541.1 - 5.2e-16 58.4 4.2 5.2e-16 58.4 4.2 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein stn_TNFRSF12A PF12191.8 CDS28542.1 - 0.019 15.2 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Saf_2TM PF18303.1 CDS28542.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain SRTM1 PF15872.5 CDS28542.1 - 0.55 10.4 2.8 7.1 6.8 0.8 2.5 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF4395 PF14340.6 CDS28543.2 - 0.12 12.7 0.7 0.34 11.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) PHD PF00628.29 CDS28544.1 - 8e-40 134.5 90.3 4.8e-11 42.4 7.8 8.7 5 3 2 7 7 7 6 PHD-finger zf-HC5HC2H PF13771.6 CDS28544.1 - 1.9e-11 44.1 1.2 1.9e-11 44.1 1.2 7.8 4 2 3 7 7 7 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDS28544.1 - 3.4e-08 33.6 1.0 3.4e-08 33.6 1.0 7.1 3 2 4 7 7 7 3 PHD-zinc-finger like domain PHD_2 PF13831.6 CDS28544.1 - 0.00018 21.0 53.7 0.011 15.3 1.8 8.0 7 1 0 7 7 7 5 PHD-finger Prok-RING_1 PF14446.6 CDS28544.1 - 0.0015 18.4 1.4 0.0015 18.4 1.4 7.3 7 0 0 7 7 7 4 Prokaryotic RING finger family 1 HMG_box_2 PF09011.10 CDS28544.1 - 0.01 16.4 0.0 0.035 14.7 0.0 1.9 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 CDS28544.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Pkinase PF00069.25 CDS28545.1 - 2e-57 194.5 0.0 2.8e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28545.1 - 1.8e-24 86.4 0.0 3.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS28545.1 - 0.00087 19.3 1.3 0.0095 15.9 0.0 2.7 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS28545.1 - 0.0016 17.9 0.4 0.0025 17.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDS28545.1 - 0.025 14.2 0.4 0.045 13.3 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CDS28545.1 - 0.029 14.0 0.4 0.065 12.8 0.4 1.6 1 0 0 1 1 1 0 RIO1 family Homeodomain PF00046.29 CDS28546.1 - 2.6e-19 68.8 5.4 4.5e-19 68.0 5.4 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 CDS28546.1 - 0.014 15.2 0.4 0.026 14.3 0.4 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CDS28546.1 - 0.043 14.0 0.3 0.083 13.0 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CDS28546.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 CDS28546.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF892 PF05974.12 CDS28546.1 - 0.17 11.9 0.3 9.1 6.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF892) IRF PF00605.17 CDS28547.1 - 9.6e-38 128.7 1.1 2.3e-37 127.5 1.1 1.7 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.9 CDS28547.1 - 7.9e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Integrase_H2C2 PF17921.1 CDS28547.1 - 7e-06 26.1 0.1 1.9e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain MH2 PF03166.14 CDS28547.1 - 2.8e-05 24.4 0.0 5.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 MH2 domain rve PF00665.26 CDS28547.1 - 0.0022 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tmemb_18A PF09771.9 CDS28548.1 - 1.6e-46 157.5 0.1 1.8e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 DUF3989 PF13150.6 CDS28548.1 - 0.42 10.4 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Transketolase_N PF00456.21 CDS28549.1 - 6.6e-45 153.5 0.0 1.2e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDS28549.1 - 3.3e-36 124.6 0.1 5.3e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDS28549.1 - 4.4e-27 94.4 0.1 8.3e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CDS28549.1 - 1.8e-12 46.8 0.0 2.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDS28549.1 - 1.9e-06 27.3 0.1 9.4e-05 21.7 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CDS28549.1 - 6.1e-05 22.9 0.5 0.00049 19.9 0.2 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 CDS28549.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain TMEM126 PF07114.11 CDS28549.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 ATG16 PF08614.11 CDS28550.1 - 0.05 13.8 42.9 54 3.9 41.7 3.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 CDS28550.1 - 0.079 12.3 24.0 0.068 12.5 14.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LPP PF04728.13 CDS28550.1 - 0.15 12.4 13.3 5 7.6 0.6 5.1 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Spc7 PF08317.11 CDS28550.1 - 0.2 10.5 37.9 0.12 11.2 21.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CDS28550.1 - 2.4 8.4 31.0 1.9 8.7 6.7 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CDS28550.1 - 4 8.1 39.9 1.1 10.0 12.4 3.5 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DcpS_C PF11969.8 CDS28550.1 - 6 7.4 7.5 22 5.6 0.6 2.8 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DUF4200 PF13863.6 CDS28550.1 - 6.9 7.1 34.1 0.06 13.7 15.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) ERM PF00769.19 CDS28550.1 - 8.6 6.1 40.9 0.65 9.8 19.3 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family KASH_CCD PF14662.6 CDS28550.1 - 9.3 6.0 41.3 1.5 8.6 23.1 2.9 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GTP_EFTU PF00009.27 CDS28551.1 - 6e-55 185.8 0.7 1.1e-54 184.9 0.7 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDS28551.1 - 4.9e-16 59.0 0.0 2.5e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDS28551.1 - 4.4e-14 52.6 2.8 1.1e-13 51.3 2.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDS28551.1 - 0.00045 20.3 0.2 0.00089 19.3 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDS28551.1 - 0.16 11.7 1.4 1.3 8.7 0.1 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation F5_F8_type_C PF00754.25 CDS28552.1 - 1.4e-12 47.9 0.0 2.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Shisa PF13908.6 CDS28552.1 - 0.59 10.3 0.0 0.59 10.3 0.0 2.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Rhomboid PF01694.22 CDS28553.1 - 1.3e-31 109.7 10.6 1.3e-31 109.7 10.6 1.7 2 0 0 2 2 2 1 Rhomboid family EF-hand_1 PF00036.32 CDS28553.1 - 0.0012 18.2 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDS28553.1 - 0.0045 17.4 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair SPT_ssu-like PF11779.8 CDS28553.1 - 0.11 12.1 2.7 0.35 10.5 2.7 1.8 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like EF-hand_8 PF13833.6 CDS28553.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Myb_DNA-bind_6 PF13921.6 CDS28555.1 - 5.9e-15 55.3 3.3 4.2e-07 30.1 0.1 4.7 2 2 2 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CDS28555.1 - 2.3e-14 53.3 7.2 2e-06 27.9 0.1 5.2 4 1 0 4 4 4 4 Myb-like DNA-binding domain Ank_2 PF12796.7 CDS28556.1 - 5.3e-13 49.4 0.1 2.2e-08 34.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS28556.1 - 1e-11 45.1 0.0 1.2e-05 25.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS28556.1 - 9.6e-10 38.5 0.0 0.0019 18.6 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 CDS28556.1 - 1.9e-08 33.9 0.3 0.021 15.3 0.0 3.7 5 0 0 5 5 5 2 Ankyrin repeat zf-MYND PF01753.18 CDS28556.1 - 1.5e-07 31.4 11.7 1.5e-07 31.4 11.7 1.9 2 0 0 2 2 2 1 MYND finger Ank_5 PF13857.6 CDS28556.1 - 0.00024 21.3 0.0 0.25 11.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DnaJ_C PF01556.18 CDS28557.1 - 1.7e-41 141.8 0.2 2.3e-41 141.3 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDS28557.1 - 4.8e-25 87.5 2.9 7.8e-25 86.8 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDS28557.1 - 6.5e-15 55.2 10.7 1.1e-14 54.6 10.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDS28557.1 - 0.072 13.1 14.8 0.21 11.6 2.9 3.4 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 CDS28557.1 - 0.29 10.8 6.9 0.63 9.7 1.3 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 CDS28557.1 - 0.37 10.8 3.9 4.6 7.3 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CDS28557.1 - 0.63 10.1 5.2 5.1 7.1 5.2 2.2 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_9 PF14369.6 CDS28557.1 - 2.3 8.6 12.1 5.3 7.4 0.4 4.1 4 0 0 4 4 4 0 zinc-ribbon Zn_Tnp_IS1 PF03811.13 CDS28557.1 - 2.7 7.8 7.4 7.8 6.3 0.2 3.4 2 1 1 3 3 3 0 InsA N-terminal domain DZR PF12773.7 CDS28557.1 - 3.9 7.6 10.0 29 4.8 10.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 CDS28557.1 - 4.8 7.4 6.8 3.4 7.9 4.1 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 Lar_restr_allev PF14354.6 CDS28557.1 - 6.4 7.2 6.7 29 5.1 0.0 3.5 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CDS28557.1 - 9.2 6.3 12.9 11 6.1 4.8 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2353 PF09789.9 CDS28558.1 - 4.3e-10 39.5 11.0 1.8e-08 34.1 7.0 2.0 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) Cep57_CLD_2 PF14197.6 CDS28558.1 - 0.025 14.7 2.6 0.025 14.7 2.6 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FapA PF03961.13 CDS28558.1 - 0.025 13.2 5.1 0.026 13.1 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SOGA PF11365.8 CDS28558.1 - 0.03 15.5 9.0 0.032 15.4 0.1 2.5 2 1 0 2 2 2 0 Protein SOGA GAS PF13851.6 CDS28558.1 - 0.1 12.0 13.5 0.66 9.3 0.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Peptidase_M16 PF00675.20 CDS28558.1 - 0.11 12.5 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) zf-C4pol PF14260.6 CDS28558.1 - 0.5 10.9 6.7 0.21 12.1 3.9 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DivIC PF04977.15 CDS28558.1 - 1.5 8.7 11.5 1.5 8.7 0.6 3.1 2 1 1 3 3 3 0 Septum formation initiator Mto2_bdg PF12808.7 CDS28558.1 - 1.8 8.9 13.9 21 5.5 0.0 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region KIAA1430 PF13879.6 CDS28558.1 - 1.9 9.3 13.6 0.25 12.1 3.2 2.2 1 1 1 2 2 2 0 KIAA1430 homologue Seryl_tRNA_N PF02403.22 CDS28558.1 - 2.5 8.4 9.4 4 7.7 3.7 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain JIP_LZII PF16471.5 CDS28558.1 - 2.9 8.1 12.3 1.1 9.5 2.3 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Fungal_TACC PF12709.7 CDS28558.1 - 4.7 7.7 11.2 1.4 9.4 3.8 3.0 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins PRKG1_interact PF15898.5 CDS28558.1 - 6.3 7.8 15.2 11 7.0 11.7 2.2 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 CDS28559.1 - 1.1e-11 44.9 21.3 1.1e-11 44.9 21.3 17.9 7 4 9 18 18 18 5 TPR/MLP1/MLP2-like protein TPR_2 PF07719.17 CDS28560.1 - 6e-13 47.8 0.3 0.0087 16.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS28560.1 - 2e-10 40.0 1.3 0.0028 17.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS28560.1 - 5.6e-10 38.6 0.1 0.028 14.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS28560.1 - 3.5e-09 36.7 0.0 0.082 13.8 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS28560.1 - 5.5e-08 32.4 0.2 0.012 15.3 0.0 5.0 5 0 0 5 5 5 2 TPR repeat TPR_6 PF13174.6 CDS28560.1 - 1.2e-07 31.9 2.9 1.4 9.7 0.0 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28560.1 - 3.8e-07 30.5 0.2 0.02 15.4 0.0 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28560.1 - 1.3e-06 28.6 0.0 0.0029 17.8 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28560.1 - 1.7e-06 28.0 1.1 0.78 10.3 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS28560.1 - 2.8e-06 27.4 0.3 0.12 12.6 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDS28560.1 - 2.9e-05 24.6 0.0 0.38 11.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28560.1 - 0.00085 19.2 0.1 1.6 8.9 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28560.1 - 0.01 15.9 0.0 16 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CDS28560.1 - 0.015 15.3 0.0 1.3 9.1 0.0 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CDS28560.1 - 0.044 13.7 0.1 8.5 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS28561.1 - 2e-39 131.8 32.4 1.4e-05 24.6 0.0 13.9 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 CDS28561.1 - 6.7e-39 128.9 36.9 9.3e-06 25.4 0.0 16.4 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28561.1 - 2.3e-35 120.9 12.8 3.5e-06 27.4 0.1 10.8 8 2 4 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 CDS28561.1 - 1.2e-34 115.5 24.0 0.00091 19.3 0.0 13.7 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_16 PF13432.6 CDS28561.1 - 3.9e-33 113.8 11.3 1.2e-05 25.8 0.1 11.3 8 3 3 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 CDS28561.1 - 7.3e-24 82.4 22.7 0.0025 18.5 0.0 11.6 6 4 6 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDS28561.1 - 3e-23 81.9 28.1 0.00038 20.7 0.1 11.4 8 3 3 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28561.1 - 2.5e-22 77.6 19.8 0.11 13.0 0.0 14.2 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDS28561.1 - 4.3e-17 61.5 12.8 0.0042 16.7 0.0 11.5 7 3 6 13 13 13 4 TPR repeat TPR_6 PF13174.6 CDS28561.1 - 2.2e-11 43.6 33.3 0.18 12.5 0.0 11.6 13 0 0 13 13 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28561.1 - 8.6e-11 41.1 26.2 1 9.5 0.0 12.8 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28561.1 - 2.2e-10 40.5 11.7 0.0035 17.5 0.1 7.2 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 CDS28561.1 - 1.3e-07 31.3 29.9 0.94 9.4 0.0 11.2 12 0 0 12 12 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS28561.1 - 4.8e-07 29.9 30.2 0.067 13.4 3.1 7.1 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CDS28561.1 - 0.064 13.9 1.1 13 6.7 0.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Band_7 PF01145.25 CDS28562.1 - 6.7e-17 62.1 2.6 1.6e-16 60.8 0.0 2.6 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CDS28562.1 - 4.7e-05 23.6 19.7 0.0016 18.6 9.5 3.5 2 2 1 3 3 3 3 Flotillin Band_7_1 PF13421.6 CDS28562.1 - 0.0048 16.6 0.9 0.0072 16.1 0.0 1.6 2 0 0 2 2 2 1 SPFH domain-Band 7 family BtpA PF03437.15 CDS28562.1 - 0.056 12.9 1.7 0.15 11.5 0.7 2.0 1 1 1 2 2 2 0 BtpA family MMR_HSR1_C PF08438.10 CDS28562.1 - 0.23 12.1 4.8 7.7 7.1 0.4 2.4 2 0 0 2 2 2 0 GTPase of unknown function C-terminal Metallophos PF00149.28 CDS28563.1 - 8.9e-36 124.3 0.7 3.3e-35 122.4 0.2 2.1 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CDS28563.1 - 1.3e-23 83.0 0.2 2.6e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CDS28563.1 - 2.5e-17 61.9 8.1 3.4e-06 26.6 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS28563.1 - 1e-14 53.4 9.8 0.00018 21.3 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS28563.1 - 1.6e-12 46.9 4.7 9.1e-06 25.3 0.4 2.8 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 CDS28563.1 - 1.3e-10 40.6 4.3 0.0059 16.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS28563.1 - 1.1e-08 35.5 3.6 0.0002 22.0 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS28563.1 - 3.3e-06 27.1 0.0 1e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS28563.1 - 8.1e-06 26.3 0.9 0.0074 16.8 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS28563.1 - 5.2e-05 23.7 0.1 1.1 10.2 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS28563.1 - 0.00019 21.6 2.8 0.00037 20.7 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDS28563.1 - 0.00024 21.6 0.5 0.063 13.9 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 CDS28563.1 - 0.00096 19.2 2.9 0.066 13.3 0.1 2.9 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 CDS28563.1 - 0.0057 16.9 2.6 4 7.8 1.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDS28563.1 - 0.011 16.0 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS28563.1 - 0.039 14.0 0.1 6.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 CDS28563.1 - 0.14 12.2 1.2 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 CDS28564.1 - 2.4e-59 200.9 0.0 3.1e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CDS28564.1 - 1.8e-39 136.0 0.0 2.7e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CDS28564.1 - 3e-39 134.9 0.0 4.7e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS28564.1 - 4.4e-05 22.4 0.0 7.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDS28564.1 - 0.00031 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Hist_deacetyl PF00850.19 CDS28565.1 - 6.3e-84 282.1 0.0 8.9e-84 281.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TSP_1 PF00090.19 CDS28566.1 - 1.2e-05 25.4 7.7 3.5e-05 23.9 7.7 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain hEGF PF12661.7 CDS28566.1 - 0.00012 22.5 23.3 0.12 13.1 6.4 4.4 3 0 0 3 3 3 3 Human growth factor-like EGF cEGF PF12662.7 CDS28566.1 - 0.052 13.5 5.3 0.058 13.3 0.0 3.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like LRR_6 PF13516.6 CDS28567.2 - 8.1e-11 41.1 12.0 0.021 14.8 0.1 7.2 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 CDS28567.2 - 0.00056 19.6 9.4 4.2 7.2 0.2 6.1 6 0 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 CDS28567.2 - 0.0024 18.2 22.2 0.27 11.7 0.7 6.6 5 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS28567.2 - 0.29 11.8 24.0 1 10.2 0.3 8.1 9 0 0 9 9 9 0 Leucine Rich Repeat AAA PF00004.29 CDS28568.1 - 2.1e-54 183.5 0.0 2.4e-42 144.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDS28568.1 - 3.7e-08 33.3 0.0 0.0012 18.6 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CDS28568.1 - 7.4e-08 32.5 0.0 0.00051 20.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 CDS28568.1 - 3.3e-06 27.6 0.2 0.022 15.2 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CDS28568.1 - 4.1e-06 26.9 0.0 0.0014 18.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CDS28568.1 - 4.3e-06 26.4 0.0 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_14 PF13173.6 CDS28568.1 - 9e-06 25.7 0.0 0.0073 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDS28568.1 - 1.1e-05 25.6 0.0 0.00019 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDS28568.1 - 3.7e-05 24.0 0.5 0.16 12.2 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDS28568.1 - 4e-05 24.2 0.0 0.014 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CDS28568.1 - 6.5e-05 22.9 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CDS28568.1 - 0.00018 21.4 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDS28568.1 - 0.00061 20.1 0.0 0.28 11.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 CDS28568.1 - 0.00072 19.8 0.0 0.099 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CDS28568.1 - 0.00078 19.4 0.2 2 8.3 0.1 3.1 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 CDS28568.1 - 0.00095 18.6 1.3 0.038 13.4 0.2 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDS28568.1 - 0.0015 18.7 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDS28568.1 - 0.0019 18.0 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDS28568.1 - 0.0024 17.7 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CDS28568.1 - 0.0045 16.6 0.8 3.4 7.2 0.1 3.0 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 CDS28568.1 - 0.0065 16.4 0.8 3.4 7.6 0.0 3.4 4 0 0 4 4 3 1 NTPase Zeta_toxin PF06414.12 CDS28568.1 - 0.0072 15.6 0.0 4.4 6.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 CDS28568.1 - 0.0096 15.2 0.0 0.06 12.5 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 CDS28568.1 - 0.011 15.7 0.6 2.6 7.9 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDS28568.1 - 0.013 16.0 0.0 6.5 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.6 CDS28568.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDS28568.1 - 0.014 15.1 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CDS28568.1 - 0.015 15.1 0.0 0.38 10.4 0.0 3.0 4 0 0 4 4 4 0 Sigma-54 interaction domain SRPRB PF09439.10 CDS28568.1 - 0.018 14.4 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 CDS28568.1 - 0.024 15.0 0.1 6.5 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDS28568.1 - 0.038 13.5 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDS28568.1 - 0.052 13.3 0.2 9 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDS28568.1 - 0.057 13.8 0.2 1.3 9.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 CDS28568.1 - 0.066 12.9 0.1 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase FeoB_N PF02421.18 CDS28568.1 - 0.1 12.2 0.7 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Parvo_NS1 PF01057.17 CDS28568.1 - 0.11 11.6 0.0 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MOEP19 PF16005.5 CDS28568.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 KH-like RNA-binding domain TniB PF05621.11 CDS28568.1 - 0.13 11.6 0.0 36 3.7 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein Nuc_deoxyri_tr2 PF15891.5 CDS28568.1 - 0.14 12.5 0.4 2.3 8.5 0.3 2.6 3 0 0 3 3 2 0 Nucleoside 2-deoxyribosyltransferase like La PF05383.17 CDS28569.1 - 1.1e-15 57.4 0.3 2.4e-15 56.3 0.3 1.6 1 0 0 1 1 1 1 La domain PHD PF00628.29 CDS28571.1 - 2.7e-09 36.8 5.7 5.8e-09 35.7 5.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDS28571.1 - 0.014 15.0 0.8 0.035 13.7 0.8 1.8 1 0 0 1 1 1 0 PHD-finger NTP_transferase PF00483.23 CDS28572.1 - 2.7e-34 118.9 0.0 3.7e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDS28572.1 - 2e-09 36.8 13.7 2e-07 30.5 0.3 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CDS28572.1 - 1.8e-05 25.2 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 CDS28572.1 - 0.047 11.8 0.0 0.073 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CDS28572.1 - 4.7 7.0 7.0 0.4 10.5 0.4 2.6 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RNA_pol_3_Rpc31 PF11705.8 CDS28573.1 - 0.0027 18.0 0.0 0.0033 17.7 0.0 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2228 PF10228.9 CDS28575.1 - 0.034 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) L_lactis_RepB_C PF06430.12 CDS28576.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus Ras PF00071.22 CDS28580.1 - 0.05 13.2 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras family RNA_polI_A34 PF08208.11 CDS28581.1 - 0.0016 18.6 10.4 0.0016 18.6 10.4 2.2 2 0 0 2 2 1 1 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 CDS28581.1 - 0.0066 16.7 8.9 0.0066 16.7 8.9 2.3 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 Mpp10 PF04006.12 CDS28581.1 - 0.0093 14.5 5.3 0.0093 14.5 5.3 2.1 2 0 0 2 2 2 1 Mpp10 protein DUF3807 PF12720.7 CDS28581.1 - 0.022 15.0 20.9 0.23 11.7 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 CDS28581.1 - 0.048 12.0 15.7 0.41 8.9 1.0 2.1 2 0 0 2 2 2 0 CDC45-like protein GAGA_bind PF06217.12 CDS28581.1 - 0.24 11.7 23.2 0.09 13.1 2.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Eapp_C PF10238.9 CDS28581.1 - 0.81 9.8 19.3 0.16 12.1 4.6 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein MecA PF05389.12 CDS28581.1 - 1.3 8.6 14.4 1.6 8.3 1.0 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) TCP PF03634.13 CDS28581.1 - 1.5 9.4 25.0 0.08 13.5 3.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor Connexin PF00029.19 CDS28581.1 - 2.4 7.9 19.5 3.4 7.4 2.4 2.2 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 CDS28581.1 - 3.2 7.9 18.6 3.7 7.7 3.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 CDS28581.1 - 6.5 5.9 9.2 0.85 8.8 0.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Rot1 PF10681.9 CDS28581.1 - 6.9 6.1 10.2 0.15 11.6 0.3 2.1 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal CobT PF06213.12 CDS28581.1 - 7.1 5.9 15.1 7.1 5.9 1.6 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 CDS28581.1 - 8 5.8 21.9 3.5 7.0 8.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CDS28581.1 - 9.5 6.0 25.3 6.7 6.4 5.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF384 PF04064.13 CDS28582.1 - 6.9e-21 73.9 3.4 7.3e-21 73.8 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 CDS28582.1 - 8.3e-16 58.2 0.4 3.6e-14 52.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF383) PUL PF08324.11 CDS28582.1 - 0.00057 19.2 2.7 0.031 13.5 0.6 2.2 1 1 1 2 2 2 2 PUL domain DUF2452 PF10504.9 CDS28583.1 - 9.1e-39 132.4 0.0 1.1e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) ubiquitin PF00240.23 CDS28584.1 - 2.9e-24 84.6 0.3 7.5e-07 28.8 0.0 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 CDS28584.1 - 7.4e-19 67.4 0.0 4.1e-06 26.5 0.0 4.1 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CDS28584.1 - 8.7e-07 29.2 0.0 0.18 12.2 0.0 3.5 2 1 1 3 3 3 2 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS28584.1 - 0.00019 21.4 0.3 6.9 6.8 0.1 4.8 3 3 1 4 4 4 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDS28584.1 - 0.017 15.6 0.8 4 8.0 0.0 3.9 4 2 0 4 4 4 0 Ubiquitin-like domain YukD PF08817.10 CDS28584.1 - 0.036 14.7 0.0 83 4.0 0.0 4.3 5 0 0 5 5 5 0 WXG100 protein secretion system (Wss), protein YukD RPAP3_C PF13877.6 CDS28585.1 - 3.9e-07 30.5 0.1 7.4e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 Dynein_attach_N PF15867.5 CDS28585.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus Dynein_attach_N PF15867.5 CDS28586.1 - 2.2e-15 56.3 0.8 3.8e-15 55.6 0.8 1.4 1 0 0 1 1 1 1 Dynein attachment factor N-terminus HMG_box PF00505.19 CDS28587.1 - 0.0025 18.2 1.6 0.0025 18.2 1.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS28587.1 - 0.0053 17.3 0.5 0.0092 16.6 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain Ion_trans PF00520.31 CDS28588.1 - 1.4e-12 47.4 16.3 2e-12 46.8 16.3 1.3 1 0 0 1 1 1 1 Ion transport protein Sugarporin_N PF11471.8 CDS28588.1 - 0.063 13.2 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Ank_2 PF12796.7 CDS28589.1 - 5.3e-16 59.0 0.1 3.5e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS28589.1 - 5e-08 33.3 0.3 3.1e-05 24.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS28589.1 - 2.1e-07 31.1 0.4 0.0045 17.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28589.1 - 2.9e-06 27.2 0.1 2.4 9.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CDS28589.1 - 0.019 15.4 0.6 3.6 8.2 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Sulf_coat_C PF12193.8 CDS28589.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal Clathrin PF00637.20 CDS28590.1 - 5.9e-09 35.9 0.5 0.0021 18.0 0.1 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CDS28590.1 - 7e-06 25.8 9.0 2.1e-05 24.3 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS28590.1 - 0.00056 20.2 9.0 0.0018 18.6 7.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3H2C3 PF17122.5 CDS28590.1 - 0.0026 17.7 12.7 0.0053 16.8 12.7 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4 PF00097.25 CDS28590.1 - 0.0049 16.7 7.8 0.013 15.4 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Endonuclease_7 PF02945.15 CDS28590.1 - 0.022 14.7 0.8 0.19 11.7 0.6 2.4 2 0 0 2 2 2 0 Recombination endonuclease VII zf-RING_UBOX PF13445.6 CDS28590.1 - 0.027 14.5 7.1 0.081 13.0 7.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CDS28590.1 - 0.095 12.7 6.9 0.23 11.4 6.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDS28590.1 - 0.24 11.0 4.8 0.54 9.9 4.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CDS28590.1 - 0.35 11.2 10.0 0.14 12.5 6.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 CDS28590.1 - 0.43 11.1 3.9 0.26 11.7 1.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 CDS28590.1 - 0.77 9.6 4.8 0.54 10.1 2.6 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_1 PF14446.6 CDS28590.1 - 1.3 9.0 8.2 0.99 9.4 5.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CDS28590.1 - 2.9 7.9 6.8 7.6 6.5 6.8 1.8 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 CDS28590.1 - 5 7.1 6.9 4.4 7.2 5.2 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) PGM_PMM_I PF02878.16 CDS28591.1 - 6.8e-38 129.5 0.0 1.4e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CDS28591.1 - 8.7e-26 90.5 0.0 2.5e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CDS28591.1 - 5.5e-14 52.3 0.0 9.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDS28591.1 - 1.3e-05 25.2 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RRM_1 PF00076.22 CDS28592.1 - 8.8e-40 134.4 0.0 1.5e-20 72.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28592.1 - 7.5e-08 32.4 0.0 0.0043 17.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CDS28592.1 - 0.0015 18.4 0.0 0.13 12.2 0.0 2.8 2 1 0 2 2 2 1 Occluded RNA-recognition motif Ribosomal_L30 PF00327.20 CDS28593.1 - 2.2e-07 30.6 0.1 6.5e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF5340 PF17275.2 CDS28593.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Ribosomal_L30_N PF08079.12 CDS28593.1 - 1.5 9.1 7.7 2.6 8.4 7.7 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain MIP-T3 PF10243.9 CDS28594.2 - 5.2e-18 65.1 0.2 1.6e-17 63.5 0.2 1.9 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain GAS PF13851.6 CDS28594.2 - 5.3e-14 52.0 19.0 5.3e-14 52.0 19.0 4.1 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding DUF2854 PF11016.8 CDS28594.2 - 0.33 10.8 1.9 15 5.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) RNR_N PF08343.10 CDS28594.2 - 0.36 10.9 7.1 2 8.5 0.5 3.3 3 0 0 3 3 3 0 Ribonucleotide reductase N-terminal Phage_GP20 PF06810.11 CDS28594.2 - 1.6 8.5 26.9 0.088 12.6 2.6 4.7 3 1 1 4 4 4 0 Phage minor structural protein GP20 KMP11 PF03037.16 CDS28594.2 - 5.1 8.0 6.3 9.4 7.1 2.7 3.0 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF1759 PF03564.15 CDS28594.2 - 5.6 6.9 9.1 0.76 9.7 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) AcetylCoA_hyd_C PF13336.6 CDS28595.2 - 4e-57 192.5 0.0 6.2e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDS28595.2 - 3.7e-19 69.5 0.0 7.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain FERM_C PF09380.10 CDS28596.2 - 5.3e-20 71.6 0.4 1.3e-19 70.3 0.4 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain RhoGEF PF00621.20 CDS28596.2 - 8.5e-17 62.0 0.1 1.9e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CDS28596.2 - 3.9e-16 59.5 12.2 6.9e-10 39.4 0.2 3.9 4 0 0 4 4 4 2 PH domain FERM_M PF00373.18 CDS28596.2 - 4e-14 53.0 0.1 1.7e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDS28596.2 - 1.8e-10 40.6 0.0 5.1e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain PH_8 PF15409.6 CDS28596.2 - 5.9e-05 23.3 0.1 0.00034 20.8 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 CDS28596.2 - 0.0055 16.5 0.3 1.3 8.8 0.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain NeA_P2 PF12312.8 CDS28596.2 - 1.1 8.6 7.5 0.34 10.3 1.4 2.9 3 0 0 3 3 3 0 Nepovirus subgroup A polyprotein SCAI PF12070.8 CDS28597.2 - 3.7e-206 686.1 0.0 4.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Protein SCAI Peptidase_M90 PF06167.12 CDS28597.2 - 0.032 13.9 0.0 0.077 12.6 0.0 1.5 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 CAP PF00188.26 CDS28598.2 - 1.3e-10 42.2 2.5 2.3e-10 41.4 2.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family 7tm_1 PF00001.21 CDS28600.2 - 2.3e-06 27.1 4.3 5.6e-06 25.9 4.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) EF-hand_1 PF00036.32 CDS28600.2 - 0.00021 20.6 0.0 0.00047 19.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDS28600.2 - 0.00029 20.5 0.0 0.00082 19.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDS28600.2 - 0.0056 17.1 0.1 0.0099 16.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDS28600.2 - 0.045 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 EF hand B5 PF03484.15 CDS28600.2 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain SIX1_SD PF16878.5 CDS28602.1 - 2e-40 137.8 2.2 2.9e-40 137.2 0.5 1.9 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDS28602.1 - 3.6e-12 45.9 1.7 9.6e-12 44.6 0.4 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDS28602.1 - 2.7e-09 36.8 0.5 2.7e-09 36.8 0.5 2.5 3 0 0 3 3 3 1 Homeobox KN domain 7tm_1 PF00001.21 CDS28603.1 - 3.5e-06 26.5 9.4 5e-06 26.0 9.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 CDS28604.1 - 4.4e-05 22.9 9.7 6.3e-05 22.4 9.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Hist_deacetyl PF00850.19 CDS28607.1 - 1e-64 219.0 0.0 1.2e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain BolA PF01722.18 CDS28608.1 - 1.7e-19 69.9 0.3 6.1e-19 68.1 0.3 1.7 1 1 0 1 1 1 1 BolA-like protein wnt PF00110.19 CDS28609.1 - 3e-66 224.1 14.1 4.2e-64 217.1 14.1 2.1 1 1 0 1 1 1 1 wnt family Dynein_light PF01221.18 CDS28610.1 - 5.3e-28 97.2 0.0 5.9e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PNP_UDP_1 PF01048.20 CDS28611.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily AcetylCoA_hyd_C PF13336.6 CDS28630.2 - 8.7e-52 175.1 0.0 1.4e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDS28630.2 - 2.8e-07 30.7 0.0 6.7e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AAA PF00004.29 CDS28632.1 - 9.3e-42 142.6 0.1 4.6e-41 140.3 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS28632.1 - 1.3e-07 31.3 0.1 3e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDS28632.1 - 4.4e-05 23.5 0.5 0.00053 20.0 0.0 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS28632.1 - 7.6e-05 23.0 0.0 0.0075 16.5 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 CDS28632.1 - 0.00012 22.5 0.1 0.0044 17.4 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CDS28632.1 - 0.00075 19.7 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CDS28632.1 - 0.00098 18.4 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CDS28632.1 - 0.0011 18.8 0.0 0.0058 16.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDS28632.1 - 0.015 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDS28632.1 - 0.015 15.9 0.1 0.054 14.0 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CDS28632.1 - 0.02 14.4 0.0 0.058 12.9 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CDS28632.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS28632.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS28632.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CDS28632.1 - 0.068 13.1 0.5 4.9 7.0 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CDS28632.1 - 0.07 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CDS28632.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_ID_OB PF16450.5 CDS28632.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Sigma54_activ_2 PF14532.6 CDS28632.1 - 0.086 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDS28632.1 - 0.088 12.5 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_3 PF07726.11 CDS28632.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CDS28632.1 - 0.12 12.5 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDS28632.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Beach PF02138.18 CDS28633.2 - 2.9e-36 125.3 0.0 5.1e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Rotamase_3 PF13616.6 CDS28633.2 - 1.9e-17 63.8 0.0 4.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CDS28633.2 - 2.7e-13 50.7 0.3 5.5e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain WD40 PF00400.32 CDS28633.2 - 0.00038 21.2 9.1 0.011 16.6 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Rotamase_2 PF13145.6 CDS28633.2 - 0.017 15.9 0.1 0.13 13.1 0.0 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain SAYSvFN PF10260.9 CDS28633.2 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) JAB PF01398.21 CDS28635.2 - 5.7e-15 55.3 0.0 2.3e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank_2 PF12796.7 CDS28636.2 - 1.4e-113 371.7 44.7 2e-17 63.5 0.3 8.4 2 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS28636.2 - 1.3e-77 255.2 19.5 1.2e-10 41.7 0.1 13.4 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS28636.2 - 2.7e-71 234.7 32.2 5.2e-10 39.4 0.5 12.9 6 4 7 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28636.2 - 5.2e-71 226.1 20.5 7e-05 22.9 0.0 17.0 17 0 0 17 17 17 15 Ankyrin repeat Ank PF00023.30 CDS28636.2 - 1.6e-65 214.9 30.9 4.2e-06 27.0 0.0 16.5 17 0 0 17 17 17 14 Ankyrin repeat Ig_3 PF13927.6 CDS28637.2 - 9.4e-19 67.8 0.0 1.1e-06 29.1 0.0 5.2 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS28637.2 - 1e-13 51.2 0.1 0.039 14.0 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 CDS28637.2 - 2.3e-13 50.1 0.3 0.00028 21.0 0.0 4.8 5 1 0 5 5 5 3 Immunoglobulin domain Ig_6 PF18452.1 CDS28637.2 - 8.4e-09 34.9 0.2 0.015 14.9 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDS28637.2 - 5.7e-08 33.0 0.3 1.8 9.0 0.0 5.3 5 0 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 CDS28637.2 - 1.1e-06 28.8 0.1 0.093 12.9 0.0 4.6 5 0 0 5 5 5 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CDS28637.2 - 0.00026 21.0 0.2 0.095 12.8 0.0 3.3 3 1 0 3 3 3 1 Izumo-like Immunoglobulin domain Aminotran_1_2 PF00155.21 CDS28638.2 - 4.5e-68 230.1 0.0 5.4e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDS28638.2 - 0.00029 19.9 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CDS28638.2 - 0.00051 18.7 0.0 0.00074 18.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDS28638.2 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ldh_2 PF02615.14 CDS28638.2 - 0.022 14.0 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Med30 PF11315.8 CDS28639.2 - 1.4e-24 87.0 11.8 2.2e-12 47.4 0.5 3.1 2 1 1 3 3 3 2 Mediator complex subunit 30 OEP PF02321.18 CDS28639.2 - 0.0018 18.1 2.8 0.0018 18.1 2.8 1.5 2 0 0 2 2 2 1 Outer membrane efflux protein Seryl_tRNA_N PF02403.22 CDS28639.2 - 0.0022 18.2 1.2 0.0022 18.2 1.2 2.3 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF1713 PF08213.11 CDS28639.2 - 0.013 15.4 21.9 0.013 15.4 21.9 1.9 1 1 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Neur_chan_memb PF02932.16 CDS28639.2 - 0.22 11.6 1.9 0.29 11.2 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CTD_bind PF04818.13 CDS28639.2 - 0.23 12.3 5.4 0.18 12.7 2.8 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Uso1_p115_C PF04871.13 CDS28639.2 - 0.51 10.7 9.9 0.097 13.0 1.8 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TipAS PF07739.13 CDS28639.2 - 2.3 8.8 6.4 0.53 10.8 1.7 2.1 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain BBP1_N PF15271.6 CDS28639.2 - 7.9 7.3 8.5 62 4.3 8.6 2.1 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DUF3800 PF12686.7 CDS28639.2 - 9.2 6.9 7.3 43 4.8 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) EMP24_GP25L PF01105.24 CDS28640.2 - 1.3e-33 116.5 1.8 7.1e-32 110.8 1.8 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5070 PF16802.5 CDS28640.2 - 0.05 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) BTB PF00651.31 CDS28642.1 - 0.051 13.8 1.3 0.14 12.4 0.3 2.2 2 1 0 2 2 2 0 BTB/POZ domain BACK PF07707.15 CDS28642.1 - 0.19 11.9 1.4 0.42 10.7 0.2 2.2 2 1 0 2 2 2 0 BTB And C-terminal Kelch Reprolysin_5 PF13688.6 CDS28646.1 - 6.6e-24 85.1 0.0 1.2e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDS28646.1 - 4.8e-19 69.0 0.0 8.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CDS28646.1 - 1.1e-11 45.4 18.1 1.1e-11 45.4 18.1 3.0 3 0 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 CDS28646.1 - 1.2e-08 35.5 0.0 2.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM17_MPD PF16698.5 CDS28646.1 - 1.6e-05 25.2 2.6 1.6e-05 25.2 2.6 4.5 3 1 1 4 4 4 2 Membrane-proximal domain, switch, for ADAM17 Reprolysin PF01421.19 CDS28646.1 - 0.00011 22.2 0.8 0.0013 18.6 0.0 2.8 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 CDS28646.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Helicase_C PF00271.31 CDS28647.1 - 4e-12 46.5 0.0 1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDS28647.1 - 1.8e-07 31.4 0.0 7.3e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDS28647.1 - 2.5e-07 31.0 0.1 7.1e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 CDS28647.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDS28647.1 - 0.0032 17.7 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain GHL13 PF14883.6 CDS28647.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 Rad17 PF03215.15 CDS28647.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 CDS28647.1 - 0.17 11.8 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase LRR_8 PF13855.6 CDS28648.1 - 3.9e-25 87.4 14.3 1.1e-12 47.5 2.1 3.9 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDS28648.1 - 6e-21 74.2 30.9 1.7e-05 25.1 0.6 5.2 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS28648.1 - 2.8e-11 42.3 16.6 0.12 13.0 0.2 7.4 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.6 CDS28648.1 - 2.1e-07 30.5 23.6 0.24 11.6 0.3 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 CDS28648.1 - 0.00011 21.8 5.5 0.064 12.8 0.4 3.0 1 1 2 3 3 3 3 Leucine-rich repeat Ldh_1_C PF02866.18 CDS28649.1 - 1.1e-05 25.4 0.0 4.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDS28649.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Nucleic_acid_bd PF13820.6 CDS28649.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative nucleic acid-binding region AAA_6 PF12774.7 CDS28650.2 - 2.6e-147 490.0 0.3 1e-146 488.1 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS28650.2 - 9.8e-110 367.4 16.2 9.8e-110 367.4 16.2 4.8 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CDS28650.2 - 2.3e-78 263.1 0.0 1.1e-77 261.0 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS28650.2 - 5.5e-77 257.8 3.8 5.5e-77 257.8 3.8 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS28650.2 - 5.3e-62 208.5 2.1 7e-53 178.8 0.0 4.5 4 0 0 4 4 4 4 P-loop containing dynein motor region MT PF12777.7 CDS28650.2 - 1.7e-46 158.8 8.2 2.9e-46 158.1 8.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CDS28650.2 - 9.3e-39 133.5 1.8 3e-37 128.5 0.0 3.2 3 1 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 CDS28650.2 - 5.9e-19 68.4 0.0 2e-05 24.6 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS28650.2 - 6.7e-14 51.9 0.3 4.5e-13 49.2 0.1 2.6 2 0 0 2 2 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDS28650.2 - 1.1e-12 48.2 0.0 7.8e-12 45.4 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CDS28650.2 - 5.3e-08 33.4 0.1 0.13 12.7 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS28650.2 - 8.2e-07 29.4 4.4 0.02 15.2 0.0 5.2 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 CDS28650.2 - 7e-05 23.4 0.0 0.87 10.1 0.0 3.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDS28650.2 - 0.00056 20.3 13.9 0.045 14.1 0.2 6.9 6 2 2 8 8 8 1 AAA ATPase domain AAA_33 PF13671.6 CDS28650.2 - 0.0009 19.4 0.6 1.9 8.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 CDS28650.2 - 0.0037 16.4 1.8 0.82 8.7 0.0 3.7 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_30 PF13604.6 CDS28650.2 - 0.013 15.2 2.7 0.77 9.5 0.3 3.0 3 0 0 3 3 3 0 AAA domain DUF16 PF01519.16 CDS28650.2 - 0.019 15.5 0.5 0.019 15.5 0.5 6.9 7 1 1 8 8 6 0 Protein of unknown function DUF16 DUF853 PF05872.12 CDS28650.2 - 0.11 11.0 5.0 8.4 4.9 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DUF3873 PF12989.7 CDS28650.2 - 0.15 12.4 0.4 0.57 10.6 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_29 PF13555.6 CDS28650.2 - 0.16 11.7 2.2 11 5.9 0.2 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain SlyX PF04102.12 CDS28650.2 - 5.9 7.6 13.7 68 4.2 1.1 5.0 3 1 0 3 3 3 0 SlyX MH2 PF03166.14 CDS28651.1 - 1.1e-65 221.4 0.0 1.4e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDS28651.1 - 2e-39 134.0 1.1 3.4e-39 133.2 1.1 1.4 1 0 0 1 1 1 1 MH1 domain LIM PF00412.22 CDS28652.1 - 1.1e-22 80.0 26.0 2.7e-11 43.5 8.8 2.1 2 0 0 2 2 2 2 LIM domain DUF4428 PF14471.6 CDS28652.1 - 0.036 14.0 4.5 0.46 10.4 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) OrfB_Zn_ribbon PF07282.11 CDS28652.1 - 0.036 14.0 3.8 0.036 14.0 3.8 3.6 2 2 2 4 4 4 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 CDS28652.1 - 0.049 13.2 17.9 1.3 8.6 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_2 PF12674.7 CDS28652.1 - 0.085 13.5 2.0 0.085 13.5 2.0 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.10 CDS28652.1 - 0.66 10.1 27.6 0.46 10.6 3.3 4.1 4 0 0 4 4 4 0 Zinc ribbon domain DUF2616 PF11077.8 CDS28652.1 - 4 7.1 11.2 6.4 6.5 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Pkinase_Tyr PF07714.17 CDS28653.1 - 1.8e-59 201.1 0.0 2.5e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS28653.1 - 4.8e-28 98.3 0.0 7.7e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.6 CDS28653.1 - 0.00096 19.4 3.1 0.014 15.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Nup54 PF13874.6 CDS28654.1 - 1.3e-32 112.8 2.9 1.3e-32 112.8 2.9 2.3 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CDS28654.1 - 0.13 13.1 55.9 0.94 10.4 30.1 3.1 2 1 1 3 3 3 0 Nucleoporin FG repeat region Baculo_11_kDa PF06143.11 CDS28655.1 - 0.004 16.7 0.3 0.0046 16.5 0.3 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family Oxysterol_BP PF01237.18 CDS28656.1 - 1.1e-66 225.2 1.4 1.4e-64 218.3 1.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDS28657.1 - 1.1e-08 35.5 0.0 1.9e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDS28657.1 - 0.00014 22.0 0.1 0.00028 21.1 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CDS28657.1 - 0.00053 19.8 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 CDS28657.1 - 0.0028 17.9 0.0 0.0091 16.3 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 CDS28657.1 - 0.021 15.2 0.2 0.077 13.4 0.2 2.0 1 1 0 1 1 1 0 Plant pleckstrin homology-like region CM1 PF03026.15 CDS28657.1 - 0.025 13.9 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein PH_9 PF15410.6 CDS28657.1 - 0.096 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SAS4 PF15460.6 CDS28657.1 - 0.18 11.9 1.2 0.83 9.8 0.2 2.5 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 ICMT PF04140.14 CDS28659.1 - 9.1e-26 90.1 0.3 2.3e-25 88.8 0.3 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDS28659.1 - 2.9e-07 30.8 0.3 2.9e-07 30.8 0.3 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CDS28659.1 - 0.00038 20.1 0.4 0.00083 18.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyoxalase PF00903.25 CDS28659.1 - 0.0084 16.3 0.0 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pro_isomerase PF00160.21 CDS28660.2 - 9.9e-14 51.9 0.0 1e-13 51.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 CDS28661.1 - 9.7e-18 64.9 0.0 1.1e-17 64.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP_bind_1 PF03029.17 CDS28662.1 - 2.8e-67 227.0 0.0 9.9e-43 146.6 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MeaB PF03308.16 CDS28662.1 - 3.6e-05 22.9 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 CDS28662.1 - 3.7e-05 23.7 0.0 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDS28662.1 - 0.00086 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CDS28662.1 - 0.00099 18.9 0.0 0.0026 17.6 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 CDS28662.1 - 0.0011 19.5 0.0 0.051 14.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDS28662.1 - 0.0013 19.1 0.0 0.0043 17.4 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.10 CDS28662.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 CDS28662.1 - 0.0015 18.5 0.0 0.0021 18.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CDS28662.1 - 0.0022 18.4 0.1 0.039 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 CDS28662.1 - 0.0023 17.2 0.0 0.0075 15.5 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_22 PF13401.6 CDS28662.1 - 0.003 17.8 0.0 0.0076 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS28662.1 - 0.0055 16.9 0.0 0.028 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CDS28662.1 - 0.014 15.7 0.0 0.053 13.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CDS28662.1 - 0.026 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 CDS28662.1 - 0.033 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDS28662.1 - 0.037 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CDS28662.1 - 0.037 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_5 PF07728.14 CDS28662.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CDS28662.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 CDS28662.1 - 0.11 12.9 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CDS28662.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CDS28662.1 - 0.17 11.1 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 CDS28662.1 - 0.22 11.4 0.1 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 NTPase POB3_N PF17292.2 CDS28663.1 - 1.6e-26 92.5 1.0 3.4e-24 85.1 0.1 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 CDS28663.1 - 5.7e-21 74.7 0.0 2.7e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CDS28663.1 - 1.4e-20 73.0 0.8 3.8e-20 71.6 0.1 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box PF00505.19 CDS28663.1 - 9.8e-16 57.9 2.9 9.8e-16 57.9 2.9 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS28663.1 - 2.3e-10 40.9 4.0 5.7e-10 39.6 4.0 1.7 1 0 0 1 1 1 1 HMG-box domain YL1 PF05764.13 CDS28663.1 - 5.8 7.0 31.7 20 5.2 31.6 1.9 1 1 0 1 1 1 0 YL1 nuclear protein I-set PF07679.16 CDS28664.2 - 0.032 14.3 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_6 PF18452.1 CDS28664.2 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.6 CDS28664.2 - 0.14 12.7 0.1 32 5.2 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Bromodomain PF00439.25 CDS28665.1 - 4.4e-21 74.7 0.0 9.8e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CDS28665.1 - 3.8e-19 68.3 12.5 1.3e-11 44.2 5.2 2.6 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 CDS28665.1 - 3.7e-12 46.6 1.6 6e-05 23.5 1.2 3.3 2 0 0 2 2 2 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MBD PF01429.19 CDS28665.1 - 1.3e-09 37.6 0.0 3.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain DDT PF02791.17 CDS28665.1 - 0.0032 17.8 2.0 0.0032 17.8 2.0 2.2 2 0 0 2 2 2 1 DDT domain PHD_2 PF13831.6 CDS28665.1 - 0.017 14.7 9.8 0.47 10.0 0.9 2.6 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 CDS28665.1 - 0.17 11.5 5.7 0.43 10.2 1.0 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain VWA_N PF08399.11 CDS28666.2 - 8.5e-31 107.0 0.0 2.2e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 VWA N-terminal VGCC_alpha2 PF08473.11 CDS28666.2 - 8.7e-15 54.4 0.3 1.7e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_3 PF13768.6 CDS28666.2 - 2.4e-11 43.8 0.0 6.9e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CDS28666.2 - 1.1e-10 42.0 0.1 2.2e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDS28666.2 - 1.2e-06 29.1 0.1 3.4e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 CDS28666.2 - 1.6e-05 24.8 0.1 0.00066 19.5 0.0 2.5 2 0 0 2 2 2 1 Cache domain DivIC PF04977.15 CDS28666.2 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator EGF PF00008.27 CDS28667.1 - 0.0035 17.6 27.1 0.21 11.9 0.2 4.6 4 0 0 4 4 4 3 EGF-like domain cEGF PF12662.7 CDS28667.1 - 0.056 13.4 0.2 0.056 13.4 0.2 4.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CDS28667.1 - 0.15 12.4 0.3 0.15 12.4 0.3 4.7 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site TSP_1 PF00090.19 CDS28667.1 - 2.2 8.6 11.4 0.11 12.7 4.5 2.6 2 0 0 2 2 2 0 Thrombospondin type 1 domain HLH PF00010.26 CDS28668.1 - 7.2e-11 41.9 1.1 1.6e-10 40.8 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SVIP PF15811.5 CDS28668.1 - 0.16 12.4 1.9 0.31 11.5 0.2 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Homeodomain PF00046.29 CDS28670.1 - 1.2e-16 60.3 5.2 1.9e-16 59.6 5.2 1.3 1 0 0 1 1 1 1 Homeodomain PRIMA1 PF16101.5 CDS28670.1 - 1.5e-05 25.0 7.5 1.8e-05 24.8 5.8 1.9 2 0 0 2 2 2 1 Proline-rich membrane anchor 1 YdaS_antitoxin PF15943.5 CDS28670.1 - 0.05 13.5 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 CDS28670.1 - 0.083 12.8 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain GrpE PF01025.19 CDS28676.1 - 2.1e-41 141.4 0.2 4.1e-41 140.4 0.2 1.5 1 0 0 1 1 1 1 GrpE Ribosomal_L18p PF00861.22 CDS28676.1 - 1.5e-05 25.3 0.0 4.1e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Dehyd-heme_bind PF09098.10 CDS28676.1 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Dor1 PF04124.12 CDS28676.1 - 0.058 12.1 1.0 0.086 11.5 1.0 1.2 1 0 0 1 1 1 0 Dor1-like family Got1 PF04178.12 CDS28677.1 - 7e-22 78.0 15.5 1.1e-21 77.3 15.5 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family FYVE PF01363.21 CDS28678.1 - 5.8e-18 64.8 10.1 1.2e-17 63.8 10.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 CDS28678.1 - 1.2e-06 29.0 0.5 9.2e-06 26.1 0.0 2.4 2 1 0 3 3 3 1 PH domain FYVE_2 PF02318.16 CDS28678.1 - 4.6e-05 23.6 7.0 0.0001 22.5 7.0 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 CDS28678.1 - 0.071 12.9 0.1 1.8 8.4 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain zf-C2HC5 PF06221.13 CDS28678.1 - 0.32 11.0 11.0 1.4 8.9 11.0 2.0 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Helicase_C_2 PF13307.6 CDS28679.2 - 4.4e-45 153.9 0.0 1.6e-44 152.1 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CDS28679.2 - 8.7e-33 113.6 0.3 1.7e-29 102.9 0.1 2.5 2 1 0 2 2 2 2 Helical and beta-bridge domain DEAD_2 PF06733.15 CDS28679.2 - 3.3e-32 111.5 1.6 3.6e-15 56.0 0.0 2.6 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.15 CDS28679.2 - 6.7e-06 26.2 0.0 4.7e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDS28679.2 - 0.039 14.2 0.1 7.4 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDS28679.2 - 0.052 13.9 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SURF4 PF02077.15 CDS28680.1 - 1.2e-99 333.3 9.0 1.3e-99 333.1 9.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CDS28680.1 - 0.0013 19.3 1.3 0.0013 19.3 1.3 3.1 3 1 1 4 4 4 1 DoxX SURF2 PF05477.11 CDS28680.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pkinase PF00069.25 CDS28681.1 - 1.4e-62 211.5 0.0 4.4e-62 209.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28681.1 - 1.5e-30 106.4 0.6 2.6e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CDS28681.1 - 3.7e-06 27.5 1.2 1e-05 26.1 1.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDS28681.1 - 3.6e-05 22.9 1.4 6.6e-05 22.0 1.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDS28681.1 - 0.00048 20.1 0.1 0.056 13.3 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS28681.1 - 0.0074 15.7 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS28681.1 - 0.013 14.8 5.3 0.019 14.3 2.5 2.5 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 CDS28681.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CDS28681.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3987 PF13148.6 CDS28681.1 - 0.11 11.5 0.6 12 4.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) SSTK-IP PF15836.5 CDS28681.1 - 0.3 11.2 1.0 0.87 9.7 0.8 1.8 1 1 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein RIO1 PF01163.22 CDS28681.1 - 0.47 10.0 3.0 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Peptidase_S8 PF00082.22 CDS28682.1 - 3.3e-45 154.6 0.5 4.3e-45 154.2 0.5 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDS28682.1 - 1.8e-23 82.4 0.2 3.1e-23 81.6 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDS28682.1 - 6.9e-20 71.6 1.3 1.3e-19 70.7 1.3 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain CAP_N PF01213.19 CDS28683.2 - 5.1e-70 236.5 0.0 6.4e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CDS28683.2 - 2.4e-56 189.7 11.8 3.2e-56 189.3 11.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CDS28683.2 - 0.00051 19.8 7.9 0.002 17.8 8.0 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C Nop PF01798.18 CDS28684.1 - 1.3e-75 253.8 0.7 1.3e-75 253.8 0.7 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDS28684.1 - 1.1e-16 61.0 3.2 2.7e-16 59.7 3.2 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain 7tm_1 PF00001.21 CDS28685.1 - 5.7e-22 78.3 15.3 5.7e-22 78.3 15.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) EMP24_GP25L PF01105.24 CDS28687.1 - 2.9e-16 59.9 0.0 5.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NTF2 PF02136.20 CDS28687.1 - 7.6e-11 42.6 0.0 1.5e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 CDS28687.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain YppG PF14179.6 CDS28687.1 - 2.9 8.6 0.0 2.9 8.6 0.0 5.2 2 1 2 4 4 4 0 YppG-like protein zf-C2H2 PF00096.26 CDS28688.2 - 1.9e-13 50.0 25.0 3.7e-05 23.9 0.9 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28688.2 - 4.6e-08 33.3 28.5 0.0017 19.0 1.1 4.7 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS28688.2 - 2.5e-06 27.7 21.9 2e-05 24.8 0.9 5.1 5 0 0 5 5 5 2 Zinc-finger double domain SET PF00856.28 CDS28688.2 - 8.8e-06 26.2 0.2 0.00033 21.1 0.2 2.7 1 1 0 1 1 1 1 SET domain zf_UBZ PF18439.1 CDS28688.2 - 0.021 14.4 3.8 4.1 7.1 0.1 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 CDS28688.2 - 0.029 14.7 5.7 0.07 13.4 5.3 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 CDS28688.2 - 0.037 14.4 10.1 3.4 8.2 1.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HypA PF01155.19 CDS28688.2 - 0.049 13.7 3.5 0.99 9.5 3.5 2.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-DNA_Pol PF08996.10 CDS28688.2 - 0.08 12.7 4.9 0.12 12.1 1.6 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 CDS28688.2 - 0.24 11.4 18.9 0.24 11.5 2.0 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS28688.2 - 0.49 10.8 9.8 15 5.9 1.1 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 CDS28688.2 - 1.1 10.1 10.3 0.4 11.5 1.7 3.4 2 1 0 3 3 3 0 zinc-ribbon family zf-BED PF02892.15 CDS28688.2 - 1.5 8.9 10.2 4.6 7.4 2.8 3.5 2 1 1 3 3 3 0 BED zinc finger C1_1 PF00130.22 CDS28688.2 - 2.1 8.3 11.3 1.5 8.8 0.7 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF629 PF04780.12 CDS28688.2 - 2.9 6.3 7.0 5.6 5.4 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) C1_4 PF07975.12 CDS28688.2 - 9.9 6.5 15.3 16 5.8 3.5 4.3 2 1 2 4 4 4 0 TFIIH C1-like domain Cadherin_3 PF16184.5 CDS28691.2 - 1.1e-67 225.0 7.5 6.1e-15 55.2 0.0 15.4 15 1 1 16 16 16 10 Cadherin-like Lectin_C PF00059.21 CDS28691.2 - 8.2e-12 45.8 1.7 6.4e-11 42.9 0.3 2.6 2 0 0 2 2 2 1 Lectin C-type domain UL45 PF05473.12 CDS28691.2 - 0.027 14.1 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Clr5 PF14420.6 CDS28691.2 - 0.038 14.2 0.3 0.082 13.1 0.3 1.5 1 0 0 1 1 1 0 Clr5 domain Calx-beta PF03160.14 CDS28691.2 - 0.088 13.0 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Calx-beta domain NAC PF01849.18 CDS28692.1 - 7.5e-22 77.1 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 NAC domain Bystin PF05291.11 CDS28694.2 - 5.9e-60 203.0 0.0 8.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Bystin Kri1 PF05178.12 CDS28694.2 - 2 9.0 9.4 3.5 8.2 9.4 1.3 1 0 0 1 1 1 0 KRI1-like family STT3 PF02516.14 CDS28695.2 - 8.4e-126 420.8 29.1 9.9e-122 407.3 25.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 CDS28695.2 - 0.0012 19.1 15.5 0.0012 19.1 15.5 3.6 3 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NADH-u_ox-rdase PF10785.9 CDS28695.2 - 0.17 12.6 6.5 11 6.8 0.1 3.9 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Sec3_C_2 PF15278.6 CDS28696.1 - 0.19 12.1 0.2 0.65 10.4 0.1 1.8 1 1 1 2 2 2 0 Sec3 exocyst complex subunit HydF_tetramer PF18133.1 CDS28697.2 - 0.07 12.9 0.1 0.17 11.6 0.1 1.8 1 1 0 1 1 1 0 Hydrogen maturase F tetramerization domain DUF3613 PF12266.8 CDS28697.2 - 0.16 11.8 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) PX PF00787.24 CDS28699.2 - 7.5e-16 58.1 0.0 1.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 PX domain Cep57_MT_bd PF06657.13 CDS28699.2 - 0.11 13.0 1.3 0.75 10.3 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ATE_C PF04377.15 CDS28700.1 - 3.3e-44 150.8 4.6 3.3e-44 150.8 4.6 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CDS28700.1 - 2.2e-20 72.8 6.9 5.8e-20 71.5 6.9 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus CdiI_2 PF18593.1 CDS28700.1 - 0.12 13.1 0.2 0.51 11.0 0.2 2.2 1 1 0 1 1 1 0 CdiI immunity protein zf-4CXXC_R1 PF10497.9 CDS28700.1 - 0.2 11.9 3.4 0.52 10.6 3.4 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ATE_C PF04377.15 CDS28701.2 - 8e-47 159.2 3.0 8e-47 159.2 3.0 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CDS28701.2 - 1.7e-16 60.3 3.3 4.4e-16 59.1 3.3 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Archease PF01951.16 CDS28702.2 - 1.2e-45 155.1 0.5 1.4e-45 155.0 0.5 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) DUF1990 PF09348.10 CDS28702.2 - 0.058 13.5 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) DUF4752 PF15944.5 CDS28702.2 - 0.086 12.9 0.1 9 6.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4752) DnaJ PF00226.31 CDS28703.1 - 9.8e-25 86.5 0.2 4.4e-24 84.4 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CDS28703.1 - 6e-05 23.2 2.3 0.00027 21.1 2.5 2.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS28703.1 - 0.19 12.1 1.9 0.65 10.4 1.9 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AIM5 PF17050.5 CDS28703.1 - 1.2 10.0 6.4 2.4 9.0 0.2 3.6 2 1 0 2 2 2 0 Altered inheritance of mitochondria 5 zf-TRAF PF02176.18 CDS28704.1 - 0.0023 18.6 3.1 0.0023 18.6 3.1 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger Sina PF03145.16 CDS28704.1 - 0.0025 17.8 0.6 0.0044 17.0 0.6 1.4 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 CDS28704.1 - 0.0067 16.3 13.9 0.0067 16.3 13.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDS28704.1 - 1 9.2 19.0 0.079 12.8 13.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CDS28704.1 - 4.9 7.6 19.6 1 9.8 15.8 1.9 2 0 0 2 2 2 0 Ring finger domain Pkinase PF00069.25 CDS28706.1 - 5.8e-63 212.7 0.0 7.2e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28706.1 - 4.4e-28 98.3 0.0 6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS28706.1 - 7.8e-05 22.1 0.3 0.00013 21.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS28706.1 - 0.0085 16.0 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDS28706.1 - 0.033 13.8 1.1 0.063 12.9 0.4 1.5 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 CDS28706.1 - 0.046 13.0 0.0 0.077 12.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CDS28706.1 - 0.097 11.6 0.4 0.15 11.0 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain 7tm_1 PF00001.21 CDS28708.2 - 4.1e-11 42.7 9.7 5.4e-11 42.3 9.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS28708.2 - 0.0023 17.4 15.5 0.0061 16.0 15.5 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Col_cuticle_N PF01484.17 CDS28708.2 - 0.049 13.7 5.3 0.12 12.4 0.0 3.1 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain DUF4231 PF14015.6 CDS28708.2 - 0.069 13.6 0.3 0.069 13.6 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) LSDAT_euk PF18139.1 CDS28709.2 - 1.5e-83 280.3 0.0 2.2e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDS28709.2 - 1.1e-15 57.5 0.1 2e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Exo_endo_phos PF03372.23 CDS28709.2 - 2.6e-09 37.0 0.0 6.6e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SR-25 PF10500.9 CDS28709.2 - 0.0017 18.0 20.4 0.032 13.9 6.4 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CDS28709.2 - 2.6 8.4 19.5 0.69 10.3 3.5 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Choline_kinase PF01633.20 CDS28711.1 - 0.022 14.4 0.1 0.023 14.3 0.1 1.0 1 0 0 1 1 1 0 Choline/ethanolamine kinase AATF-Che1 PF13339.6 CDS28711.1 - 0.044 14.5 0.2 0.051 14.2 0.2 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PH PF00169.29 CDS28712.1 - 4.7e-06 27.0 0.1 2.3e-05 24.8 0.1 2.2 1 1 0 1 1 1 1 PH domain Anillin PF08174.11 CDS28712.1 - 0.0027 18.2 0.0 0.011 16.1 0.0 2.2 1 0 0 1 1 1 1 Cell division protein anillin DUF3719 PF12516.8 CDS28712.1 - 0.043 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) CR6_interact PF10147.9 CDS28713.1 - 9.7e-30 103.8 17.8 1.1e-29 103.6 17.8 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CorA PF01544.18 CDS28713.1 - 0.11 11.8 1.7 0.15 11.4 1.0 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Med9 PF07544.13 CDS28713.1 - 0.12 12.5 6.1 0.23 11.6 6.1 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 EPL1 PF10513.9 CDS28713.1 - 1.7 9.0 9.8 2.8 8.3 9.4 1.6 1 1 0 1 1 1 0 Enhancer of polycomb-like FapA PF03961.13 CDS28713.1 - 3.6 6.1 9.1 5.9 5.4 9.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 CDS28713.1 - 3.9 7.7 13.4 5.5 7.2 13.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Chromo PF00385.24 CDS28714.1 - 2.1e-15 56.3 2.6 3.8e-15 55.5 2.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CBX7_C PF17218.3 CDS28714.1 - 8.2e-11 41.4 0.3 2.7e-10 39.8 0.3 2.0 1 0 0 1 1 1 1 CBX family C-terminal motif Tudor-knot PF11717.8 CDS28714.1 - 0.79 9.7 2.7 1.5 8.8 2.7 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Miga PF10265.9 CDS28714.1 - 2.2 7.1 3.9 3.7 6.4 3.9 1.3 1 0 0 1 1 1 0 Mitoguardin LSDAT_euk PF18139.1 CDS28715.2 - 9.6e-85 284.2 0.0 1.4e-84 283.6 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDS28715.2 - 1.2e-17 63.9 0.1 2e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ank_2 PF12796.7 CDS28715.2 - 0.069 13.7 0.1 0.5 11.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Peptidase_A22B PF04258.13 CDS28716.2 - 4.2e-62 210.3 11.1 7.3e-41 140.6 3.3 2.1 1 1 1 2 2 2 2 Signal peptide peptidase DUF1772 PF08592.11 CDS28716.2 - 0.12 12.7 2.4 5.7 7.3 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) RRM_1 PF00076.22 CDS28717.2 - 1.2e-24 85.9 0.1 6.5e-08 32.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3195 PF11424.8 CDS28717.2 - 0.047 13.7 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) Adaptin_N PF01602.20 CDS28718.1 - 1.3e-117 393.5 7.1 1.3e-117 393.5 7.1 1.7 2 0 0 2 2 2 1 Adaptin N terminal region AP3D1 PF06375.11 CDS28718.1 - 2e-28 99.7 10.5 2e-28 99.7 10.5 2.7 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 Cnd1 PF12717.7 CDS28718.1 - 1.2e-14 54.7 0.6 4.4e-09 36.6 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDS28718.1 - 1.2e-07 32.0 0.2 0.16 12.4 0.0 4.9 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 CDS28718.1 - 0.00013 21.9 0.2 0.41 11.0 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat RTP1_C1 PF10363.9 CDS28718.1 - 0.0011 19.1 1.3 2.3 8.4 0.0 3.0 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 AP4E_app_platf PF14807.6 CDS28718.1 - 0.0068 16.7 0.1 0.026 14.9 0.1 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Syntaxin PF00804.25 CDS28718.1 - 0.056 13.1 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Syntaxin Tti2 PF10521.9 CDS28718.1 - 0.67 9.4 6.8 0.27 10.7 0.1 3.0 3 0 0 3 3 3 0 Tti2 family RRM_1 PF00076.22 CDS28720.1 - 2.9e-23 81.5 0.4 6.2e-11 42.0 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28720.1 - 1.2e-07 31.8 0.1 1.8e-05 24.7 0.1 2.9 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS28720.1 - 0.00039 20.3 0.4 0.33 11.0 0.1 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Involucrin2 PF06994.11 CDS28720.1 - 0.58 10.3 9.9 1.2 9.3 8.2 2.2 2 0 0 2 2 2 0 Involucrin SAM_1 PF00536.30 CDS28721.2 - 4.3e-21 75.1 0.0 2.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS28721.2 - 1.6e-15 56.9 0.0 1.8e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) CaMBD PF02888.16 CDS28721.2 - 0.81 9.9 3.9 0.4 10.9 0.2 2.2 2 0 0 2 2 2 0 Calmodulin binding domain Vps35 PF03635.17 CDS28722.1 - 2.1e-175 585.3 0.0 2.8e-175 584.9 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3446 PF11928.8 CDS28723.1 - 0.7 10.2 5.0 1.9 8.8 0.2 2.8 3 0 0 3 3 3 0 Early growth response N-terminal domain LSM PF01423.22 CDS28724.1 - 9.4e-08 31.6 0.1 1.2e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain LRR_9 PF14580.6 CDS28725.1 - 1.1e-11 44.5 6.6 2.3e-08 33.8 5.1 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CDS28725.1 - 4.3e-09 36.5 14.3 0.00012 22.4 2.0 5.0 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS28725.1 - 2.5e-07 30.3 6.7 0.0068 16.1 1.3 3.2 1 1 0 2 2 2 2 Leucine rich repeat U3_snoRNA_assoc PF08297.11 CDS28725.1 - 3.2 8.5 11.1 6.6 7.5 2.0 3.9 3 0 0 3 3 3 0 U3 snoRNA associated Diphthamide_syn PF01866.17 CDS28726.1 - 3.1e-63 214.0 0.1 3.7e-63 213.8 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein S-AdoMet_synt_C PF02773.16 CDS28727.1 - 1e-68 229.6 0.0 1.8e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDS28727.1 - 4.7e-46 155.9 0.0 9.8e-46 154.9 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDS28727.1 - 1.1e-42 144.7 0.2 2.7e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CDS28727.1 - 0.027 13.2 0.0 0.056 12.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Pesticin PF16754.5 CDS28727.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term Ras PF00071.22 CDS28728.1 - 8.3e-11 41.7 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS28728.1 - 0.00013 22.1 0.0 0.0004 20.6 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 CDS28728.1 - 0.00016 21.0 0.1 0.0003 20.1 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDS28728.1 - 0.00032 21.1 0.0 0.0006 20.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS28728.1 - 0.0016 18.2 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain SRPRB PF09439.10 CDS28728.1 - 0.0034 16.9 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EF-hand_10 PF14788.6 CDS28728.1 - 0.0076 16.1 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CDS28728.1 - 0.021 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 EF hand Arf PF00025.21 CDS28728.1 - 0.034 13.6 0.1 0.22 10.9 0.1 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family EF_assoc_2 PF08356.12 CDS28728.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 EF hand associated ATP_bind_1 PF03029.17 CDS28728.1 - 0.17 11.7 0.1 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L5 PF00281.19 CDS28730.1 - 1.6e-21 76.4 0.1 3.9e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 CDS28730.1 - 2e-13 50.3 0.0 1.1e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Calici_coat PF00915.20 CDS28731.1 - 0.00047 19.1 0.1 0.0007 18.6 0.1 1.2 1 0 0 1 1 1 1 Calicivirus coat protein CREPT PF16566.5 CDS28732.1 - 4.2e-40 137.3 4.8 8.2e-40 136.4 4.8 1.5 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CDS28732.1 - 5.1e-12 46.4 0.1 2.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 CDS28732.1 - 0.003 17.6 0.6 0.0083 16.1 0.0 1.9 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 UPF0242 PF06785.11 CDS28732.1 - 0.1 12.7 3.8 0.21 11.7 3.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ING PF12998.7 CDS28732.1 - 0.29 11.7 4.1 0.27 11.8 2.2 2.2 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ATG16 PF08614.11 CDS28732.1 - 0.45 10.7 9.6 0.071 13.3 4.9 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AIP3 PF03915.13 CDS28732.1 - 1.9 7.5 7.0 0.78 8.8 4.6 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 ANAPC4_WD40 PF12894.7 CDS28735.2 - 4.4e-05 23.7 0.0 0.00099 19.4 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS28735.2 - 0.0008 20.2 4.5 0.66 10.9 0.1 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Ras PF00071.22 CDS28735.2 - 0.0095 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Ras family TGF_beta PF00019.20 CDS28737.1 - 8.4e-24 84.5 4.0 1.8e-23 83.5 4.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain DAN PF03045.15 CDS28737.1 - 0.034 14.2 4.1 0.073 13.1 4.1 1.6 1 0 0 1 1 1 0 DAN domain RT_RNaseH PF17917.1 CDS28738.1 - 4.1e-11 43.1 0.1 8.9e-11 42.0 0.0 1.5 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS28738.1 - 3.9e-09 36.4 0.0 7.5e-09 35.5 0.0 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SLX9 PF15341.6 CDS28739.1 - 0.03 14.7 0.6 0.044 14.2 0.6 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 HMG_box PF00505.19 CDS28740.1 - 1.5e-10 41.4 0.8 5.8e-05 23.4 0.1 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS28740.1 - 0.00022 21.7 1.1 0.039 14.5 0.0 2.6 2 1 0 2 2 2 2 HMG-box domain SAP PF02037.27 CDS28740.1 - 0.002 17.8 0.0 0.0073 16.0 0.0 2.0 1 0 0 1 1 1 1 SAP domain Slx4 PF09494.10 CDS28740.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease DUF2508 PF10704.9 CDS28741.1 - 0.04 14.1 0.3 0.04 14.1 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2508) FUSC PF04632.12 CDS28741.1 - 2.2 6.7 4.0 2.9 6.3 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PDZ PF00595.24 CDS28742.1 - 3.9e-12 46.4 0.2 4.8e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDS28742.1 - 1.3e-10 40.9 0.0 5.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDS28742.1 - 0.0016 18.7 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Gla PF00594.20 CDS28742.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.2 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain bZIP_2 PF07716.15 CDS28745.1 - 3e-09 36.8 9.0 3e-09 36.8 9.0 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS28745.1 - 0.098 12.8 9.0 0.18 11.9 9.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 CDS28745.1 - 0.39 11.1 4.1 3.7 7.9 0.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family Forkhead PF00250.18 CDS28746.1 - 6.2e-26 90.5 0.7 1.3e-25 89.5 0.7 1.4 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 CDS28746.1 - 0.015 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 linker histone H1 and H5 family Ribosomal_L22 PF00237.19 CDS28747.1 - 4.7e-35 119.9 0.1 7.4e-35 119.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PCNP PF15473.6 CDS28748.1 - 1.2e-27 97.6 4.6 1.4e-27 97.4 4.6 1.1 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family BRO1 PF03097.18 CDS28749.1 - 2e-49 168.4 4.0 2.3e-49 168.2 0.4 2.5 3 0 0 3 3 3 1 BRO1-like domain PDZ PF00595.24 CDS28749.1 - 1.6e-06 28.4 0.1 3.6e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS28749.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS28749.1 - 0.0036 17.6 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Bac_export_2 PF01312.19 CDS28749.1 - 0.022 14.0 0.1 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Rpn3_C PF08375.11 CDS28749.1 - 0.033 14.6 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal BRO1 PF03097.18 CDS28750.1 - 0.0079 15.0 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain FGGY_N PF00370.21 CDS28752.1 - 4.6e-68 229.4 0.1 6.3e-68 229.0 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDS28752.1 - 1.2e-40 139.4 0.1 4.3e-40 137.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 CDS28752.1 - 0.022 12.9 0.1 0.034 12.4 0.1 1.2 1 0 0 1 1 1 0 Hsp70 protein FGGY_N PF00370.21 CDS28753.1 - 6.4e-65 219.1 0.2 9.1e-65 218.6 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDS28753.1 - 2.5e-41 141.6 0.1 3.6e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RRM_1 PF00076.22 CDS28754.1 - 2.4e-41 139.4 0.0 2.9e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28754.1 - 2.1e-06 27.7 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CDS28754.1 - 0.00013 21.6 0.0 0.11 12.1 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CDS28754.1 - 0.043 13.5 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain CTNNBL PF08216.11 CDS28755.1 - 3.6e-30 104.2 1.9 3.6e-30 104.2 0.2 1.9 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear CREPT PF16566.5 CDS28755.1 - 0.046 13.9 1.9 0.17 12.1 0.2 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FeoB_Cyto PF17910.1 CDS28755.1 - 0.65 10.6 5.1 1.7 9.3 0.9 3.0 3 0 0 3 3 3 0 FeoB cytosolic helical domain PMSR PF01625.21 CDS28756.1 - 4.5e-61 205.5 0.0 5.2e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.25 CDS28757.2 - 4.3e-68 229.5 0.0 8.8e-67 225.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CDS28757.2 - 6.2e-53 176.8 0.0 3.4e-16 59.1 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CDS28757.2 - 4.1e-33 114.8 0.0 1.4e-32 113.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS28757.2 - 5.5e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF5547 PF17701.1 CDS28757.2 - 0.2 11.5 0.4 29 4.6 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5547) UPF0020 PF01170.18 CDS28761.1 - 3.7e-06 26.8 0.2 0.0002 21.1 0.2 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CDS28761.1 - 0.0062 16.3 0.0 0.092 12.4 0.0 2.2 2 0 0 2 2 2 1 DNA methylase SepSecS PF05889.13 CDS28762.1 - 4.4e-105 351.6 0.0 3.6e-56 190.6 0.0 3.0 2 1 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Hormone_3 PF00159.18 CDS28763.1 - 3.2e-07 30.3 0.1 6.8e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide RRM_1 PF00076.22 CDS28764.1 - 8.4e-17 60.8 0.0 1.2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.6 CDS28766.2 - 0.019 15.4 0.0 0.033 14.6 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 CDS28766.2 - 0.091 12.4 0.1 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 EF hand PEGSRP PF07623.11 CDS28767.1 - 0.22 11.3 0.6 0.55 10.1 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Yuri_gagarin PF15934.5 CDS28768.1 - 0.014 15.2 0.0 0.015 15.2 0.0 1.0 1 0 0 1 1 1 0 Yuri gagarin Beta-lactamase2 PF13354.6 CDS28769.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family WD40 PF00400.32 CDS28771.1 - 7.8e-34 115.2 21.3 2.8e-06 28.0 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CDS28771.1 - 1.6e-09 37.5 1.4 1.6e-09 37.5 1.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDS28771.1 - 0.00033 20.5 5.0 0.00045 20.0 0.5 2.5 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 CDS28771.1 - 0.0024 18.1 0.0 10 6.5 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS28771.1 - 0.0044 15.7 1.3 0.064 11.9 0.3 2.9 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDS28771.1 - 0.006 15.4 1.2 0.055 12.2 0.2 2.8 2 1 1 3 3 3 1 Nup133 N terminal like GYF PF02213.16 CDS28772.1 - 1.7e-17 62.8 0.2 3.7e-17 61.7 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDS28772.1 - 0.038 13.8 0.5 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 GYF domain 2 Sec63 PF02889.16 CDS28773.1 - 8.8e-20 70.9 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 CDS28773.1 - 2.4e-10 40.7 0.0 1.2e-08 35.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS28773.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cdd1 PF11731.8 CDS28773.1 - 0.023 14.9 0.0 0.091 13.0 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity locus PI3Ka PF00613.20 CDS28774.1 - 1.3e-39 135.5 1.2 2.1e-39 134.9 1.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CDS28774.1 - 5.2e-38 131.3 0.2 8.5e-25 88.0 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CDS28774.1 - 0.00027 20.4 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 CDS28774.1 - 0.02 14.8 0.1 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Requiem_N PF14051.6 CDS28775.1 - 1.9e-25 88.8 1.0 1.9e-25 88.8 1.0 2.1 2 0 0 2 2 2 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 CDS28775.1 - 2.7e-18 65.6 25.0 2.8e-12 46.3 4.6 3.9 2 1 2 4 4 4 2 PHD-finger zf-C2H2_4 PF13894.6 CDS28775.1 - 0.004 17.9 0.4 0.004 17.9 0.4 5.4 7 0 0 7 7 7 1 C2H2-type zinc finger C1_1 PF00130.22 CDS28775.1 - 0.005 16.7 0.7 0.005 16.7 0.7 4.1 4 1 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2 PF00096.26 CDS28775.1 - 0.071 13.6 0.6 0.071 13.6 0.6 5.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type PHD_2 PF13831.6 CDS28775.1 - 0.09 12.3 0.2 0.09 12.3 0.2 4.0 4 1 0 4 4 4 0 PHD-finger PHD_4 PF16866.5 CDS28775.1 - 0.54 10.4 21.4 0.053 13.6 8.9 3.7 2 1 1 3 3 3 0 PHD-finger Nucleoporin_FG2 PF15967.5 CDS28776.1 - 5.7e-25 87.9 69.3 6.1e-25 87.8 12.8 2.3 1 1 1 2 2 2 2 Nucleoporin FG repeated region Golgin_A5 PF09787.9 CDS28776.1 - 0.0017 17.9 10.8 0.0022 17.5 10.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 APG17 PF04108.12 CDS28776.1 - 0.0024 17.0 10.3 0.0038 16.4 10.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 Sec39 PF08314.11 CDS28776.1 - 0.0035 15.9 3.3 0.0045 15.5 2.8 1.3 1 1 0 1 1 1 1 Secretory pathway protein Sec39 GvpK PF05121.12 CDS28776.1 - 0.025 14.6 4.0 0.042 13.9 1.3 2.3 2 1 1 3 3 2 0 Gas vesicle protein K HBD PF18534.1 CDS28776.1 - 0.033 14.3 0.4 0.072 13.2 0.4 1.5 1 0 0 1 1 1 0 Helical bundle domain Apolipoprotein PF01442.18 CDS28776.1 - 0.05 13.5 2.9 0.09 12.6 2.9 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CDS28776.1 - 0.052 13.6 8.8 0.19 11.8 1.9 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GFD1 PF17331.2 CDS28776.1 - 0.073 13.3 1.7 0.18 12.0 1.7 1.7 1 0 0 1 1 1 0 GFD1 mRNA transport factor Wbp11 PF09429.10 CDS28776.1 - 0.15 12.5 3.5 0.4 11.1 3.5 1.8 1 0 0 1 1 1 0 WW domain binding protein 11 DUF4618 PF15397.6 CDS28776.1 - 0.16 11.4 8.0 0.24 10.8 2.3 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 CDS28776.1 - 0.33 11.2 2.3 1.9 8.8 1.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.6 CDS28776.1 - 0.35 10.4 8.9 0.16 11.5 4.7 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DASH_Dad3 PF08656.10 CDS28776.1 - 0.36 10.9 5.7 2 8.6 1.0 2.9 2 1 0 2 2 2 0 DASH complex subunit Dad3 CCDC-167 PF15188.6 CDS28776.1 - 0.51 10.7 5.0 9.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MSA-2c PF12238.8 CDS28776.1 - 0.76 9.7 11.0 0.42 10.6 7.1 2.3 2 1 0 2 2 2 0 Merozoite surface antigen 2c Spc7 PF08317.11 CDS28776.1 - 0.82 8.5 9.8 1.5 7.6 9.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 CDS28776.1 - 0.84 9.5 4.9 2.5 7.9 3.6 2.0 1 1 1 2 2 2 0 PIN like domain CEP63 PF17045.5 CDS28776.1 - 0.96 9.3 11.5 0.53 10.1 5.1 2.1 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa CENP-F_leu_zip PF10473.9 CDS28776.1 - 1 9.4 9.9 0.28 11.2 0.6 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CDS28776.1 - 1.2 9.6 7.3 13 6.3 2.2 3.0 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Med10 PF09748.9 CDS28776.1 - 1.3 9.0 5.3 1.1 9.3 0.2 2.8 1 1 2 3 3 3 0 Transcription factor subunit Med10 of Mediator complex DUF1664 PF07889.12 CDS28776.1 - 1.5 8.9 8.7 11 6.1 1.8 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CDS28776.1 - 2.5 8.7 7.5 13 6.4 2.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TBCC_N PF16752.5 CDS28776.1 - 3.2 8.2 10.3 3.8 8.0 1.8 2.9 1 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain CdvA PF18822.1 CDS28776.1 - 6.6 6.6 10.7 8.5 6.2 3.3 3.0 1 1 2 3 3 3 0 CdvA-like coiled-coil domain FAM91_C PF14648.6 CDS28777.1 - 4.9e-101 338.7 0.0 1e-100 337.6 0.0 1.5 2 0 0 2 2 2 1 FAM91 C-terminus FAM91_N PF14647.6 CDS28777.1 - 2.4e-93 312.9 0.0 3.3e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Tetraspanin PF00335.20 CDS28778.1 - 2.8e-07 30.5 0.5 3.4e-07 30.2 0.5 1.1 1 0 0 1 1 1 1 Tetraspanin family zf-C2H2_jaz PF12171.8 CDS28779.1 - 5.5e-07 29.7 1.6 9.4e-07 29.0 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS28779.1 - 1e-06 28.9 1.7 1.7e-06 28.2 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CDS28779.1 - 0.00038 20.1 1.8 0.0007 19.3 1.8 1.5 1 0 0 1 1 1 1 U1 zinc finger SNRNP27 PF08648.12 CDS28779.1 - 0.012 15.6 0.3 0.062 13.4 0.0 2.4 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 CDS28779.1 - 0.14 12.7 1.0 0.3 11.6 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SPOC PF07744.13 CDS28780.2 - 8.5e-17 61.5 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 CDS28780.2 - 9.8e-15 54.1 0.0 4.5e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS28780.2 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 CDS28780.2 - 0.047 13.5 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif RAB3GAP2_N PF14655.6 CDS28782.1 - 7.9e-21 74.8 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 CDS28782.1 - 0.0011 17.4 0.2 1.7 6.8 0.1 2.9 2 1 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus Syntaxin PF00804.25 CDS28783.1 - 1.2e-48 165.5 13.9 1.2e-48 165.5 13.9 1.5 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CDS28783.1 - 4.6e-18 64.9 2.1 1.3e-17 63.5 2.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CDS28783.1 - 8.1e-06 26.1 11.3 4.7e-05 23.7 1.7 2.4 2 1 0 2 2 2 1 Syntaxin-like protein DUF2205 PF10224.9 CDS28783.1 - 0.0021 18.0 6.1 0.22 11.6 3.0 2.6 2 0 0 2 2 2 1 Short coiled-coil protein DUF2951 PF11166.8 CDS28783.1 - 0.0034 17.5 1.2 0.0034 17.5 1.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) FAM167 PF11652.8 CDS28783.1 - 0.0061 17.0 11.2 1.2 9.7 0.3 3.3 3 0 0 3 3 3 2 FAM167 DUF4600 PF15372.6 CDS28783.1 - 0.0078 16.7 1.7 0.0078 16.7 1.7 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4600) Alanine_zipper PF11839.8 CDS28783.1 - 0.022 15.1 3.2 4.5 7.7 0.0 3.0 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Lzipper-MIP1 PF14389.6 CDS28783.1 - 0.024 14.9 2.6 0.029 14.6 0.1 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 T2SSF PF00482.23 CDS28783.1 - 0.03 14.3 4.1 2.3 8.2 0.1 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F SKA1 PF07160.12 CDS28783.1 - 0.035 13.9 9.9 0.16 11.8 2.9 2.5 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 COG2 PF06148.11 CDS28783.1 - 0.036 14.2 7.3 1 9.5 0.4 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 CDS28783.1 - 0.049 14.1 9.1 0.49 10.9 3.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1798 PF08807.10 CDS28783.1 - 0.06 13.5 5.4 0.88 9.7 0.1 2.9 2 1 1 3 3 3 0 Bacterial domain of unknown function (DUF1798) Mid2 PF04478.12 CDS28783.1 - 0.063 13.1 0.4 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MCPsignal PF00015.21 CDS28783.1 - 0.064 13.1 10.1 0.036 13.9 2.0 2.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Serine_rich PF08824.10 CDS28783.1 - 0.071 13.1 2.9 0.39 10.7 0.0 2.5 1 1 0 2 2 2 0 Serine rich protein interaction domain DUF4988 PF16378.5 CDS28783.1 - 0.076 12.7 5.9 0.16 11.7 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function TMPIT PF07851.13 CDS28783.1 - 0.076 12.2 6.0 0.79 8.9 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein TraF_2 PF13729.6 CDS28783.1 - 0.077 12.4 6.3 0.25 10.7 0.9 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein ETRAMP PF09716.10 CDS28783.1 - 0.11 12.6 2.4 0.26 11.4 2.4 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Atg14 PF10186.9 CDS28783.1 - 0.12 11.4 8.0 2.6 7.1 3.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 CDS28783.1 - 0.19 11.9 8.7 3.3 7.9 0.3 2.6 2 1 0 2 2 2 0 Tropomyosin like DUF2203 PF09969.9 CDS28783.1 - 0.2 12.4 12.5 2.2 9.0 3.1 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.11 CDS28783.1 - 0.22 12.0 7.2 8.4 6.9 0.1 3.8 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) LPP PF04728.13 CDS28783.1 - 0.22 12.0 7.8 1.3 9.5 0.6 3.1 2 2 0 2 2 2 0 Lipoprotein leucine-zipper T3SSipB PF16535.5 CDS28783.1 - 0.24 11.9 9.2 4.1 7.8 4.0 2.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB AKNA PF12443.8 CDS28783.1 - 0.26 12.0 2.7 4.4 8.0 0.1 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor Insulin_TMD PF17870.1 CDS28783.1 - 0.3 11.2 2.6 0.57 10.3 2.6 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF16 PF01519.16 CDS28783.1 - 0.32 11.5 16.2 2.7 8.5 6.9 3.0 1 1 3 4 4 4 0 Protein of unknown function DUF16 KRAP_IP3R_bind PF14722.6 CDS28783.1 - 0.39 10.5 4.4 1.8 8.3 0.1 2.8 3 0 0 3 3 3 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DUF2207 PF09972.9 CDS28783.1 - 0.48 9.1 4.6 0.12 11.1 0.4 1.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) UPF0242 PF06785.11 CDS28783.1 - 0.72 9.9 12.0 2.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 CDS28783.1 - 0.75 7.7 15.6 19 3.0 1.0 2.2 1 1 1 2 2 2 0 Prominin DUF745 PF05335.13 CDS28783.1 - 1.3 8.7 8.6 3.4 7.3 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 CDS28783.1 - 1.6 8.8 13.8 3 7.9 2.9 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) PCRF PF03462.18 CDS28783.1 - 1.6 8.5 14.1 0.59 10.0 4.4 2.7 1 1 2 3 3 3 0 PCRF domain Spectrin PF00435.21 CDS28783.1 - 1.7 9.1 12.5 8.1 7.0 0.4 3.0 1 1 0 2 2 2 0 Spectrin repeat Fib_alpha PF08702.10 CDS28783.1 - 1.9 8.7 16.4 3.2 7.9 1.6 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CDS28783.1 - 2.4 8.5 11.9 3.4 8.1 2.7 2.2 2 0 0 2 2 2 0 Fez1 Med9 PF07544.13 CDS28783.1 - 2.7 8.1 10.8 2.4 8.3 2.3 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 P4Ha_N PF08336.11 CDS28783.1 - 3.9 7.5 9.6 11 6.1 0.2 3.2 2 2 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Rx_N PF18052.1 CDS28783.1 - 4 7.8 8.1 21 5.5 0.2 2.8 2 2 0 2 2 2 0 Rx N-terminal domain YabA PF06156.13 CDS28783.1 - 6.8 7.4 10.0 16 6.2 1.2 3.0 1 1 2 3 3 3 0 Initiation control protein YabA SlyX PF04102.12 CDS28783.1 - 7.4 7.3 12.6 0.89 10.2 2.5 3.5 2 2 2 4 4 3 0 SlyX Adeno_E3_CR2 PF02439.15 CDS28783.1 - 8.7 6.2 10.5 15 5.5 10.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Laminin_II PF06009.12 CDS28783.1 - 8.9 6.3 11.0 5.2 7.1 2.6 2.9 2 1 0 2 2 2 0 Laminin Domain II MtrG PF04210.13 CDS28783.1 - 9.7 6.1 8.3 0.65 9.9 1.4 2.7 4 0 0 4 4 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Thioredoxin_16 PF18569.1 CDS28784.1 - 1.3e-10 41.3 0.0 4e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Katanin_con80 PF13925.6 CDS28784.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Mod_r PF07200.13 CDS28785.1 - 1.7e-29 102.8 18.5 2.2e-29 102.5 18.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3209 PF11483.8 CDS28785.1 - 0.0025 18.2 2.1 0.023 15.1 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3209) SATase_N PF06426.14 CDS28785.1 - 0.02 15.3 1.2 0.037 14.4 1.2 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Afi1 PF07792.12 CDS28785.1 - 0.33 11.4 4.9 0.49 10.9 4.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CorA PF01544.18 CDS28785.1 - 0.42 9.9 6.1 0.53 9.6 6.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GNAT_acetyltran PF12746.7 CDS28785.1 - 0.79 9.2 5.6 0.39 10.2 3.2 1.6 1 1 0 2 2 2 0 GNAT acetyltransferase TGT PF01702.18 CDS28786.1 - 3.3e-45 154.8 0.0 4e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LRR_8 PF13855.6 CDS28787.1 - 8.2e-19 67.1 16.4 4.2e-12 45.6 2.7 3.5 2 1 2 4 4 4 3 Leucine rich repeat I-set PF07679.16 CDS28787.1 - 4e-10 39.6 0.0 7.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS28787.1 - 1.1e-09 38.7 0.0 4.6e-09 36.7 0.0 2.1 2 0 0 2 2 1 1 Immunoglobulin domain LRR_4 PF12799.7 CDS28787.1 - 3e-08 33.8 10.8 0.00098 19.5 0.3 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Ig_2 PF13895.6 CDS28787.1 - 6.4e-07 29.6 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS28787.1 - 1.4e-06 28.3 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 CDS28787.1 - 8.9e-06 25.6 9.7 4.5 8.2 0.6 5.5 5 0 0 5 5 4 2 Leucine Rich Repeat CYYR1 PF10873.8 CDS28787.1 - 0.00037 21.0 0.4 0.00091 19.7 0.3 1.7 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 V-set PF07686.17 CDS28787.1 - 0.0013 18.9 0.0 0.051 13.8 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 CDS28787.1 - 0.012 15.6 11.3 7.8 6.8 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat DUF2178 PF09946.9 CDS28787.1 - 0.028 14.6 0.5 0.053 13.7 0.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) LRRCT PF01463.24 CDS28787.1 - 0.063 13.8 0.4 0.22 12.2 0.4 2.1 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain DUF3481 PF11980.8 CDS28787.1 - 0.097 12.4 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein RCR PF12273.8 CDS28787.1 - 0.099 13.3 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red V-set_CD47 PF08204.11 CDS28787.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Adeno_E3_CR2 PF02439.15 CDS28787.1 - 0.17 11.7 4.0 0.32 10.8 4.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CBP_BcsF PF11120.8 CDS28787.1 - 0.18 11.9 0.1 27 5.0 0.0 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF LRR_9 PF14580.6 CDS28787.1 - 0.2 11.2 4.0 0.33 10.4 2.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeat HTH_48 PF17906.1 CDS28788.1 - 1.3e-15 57.2 0.1 1.6e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase CopK PF11525.8 CDS28788.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein K DUF998 PF06197.13 CDS28789.1 - 0.016 14.8 15.4 0.028 14.0 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) CrgA PF06781.12 CDS28789.1 - 0.11 12.6 0.4 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 Cell division protein CrgA HTH_51 PF18558.1 CDS28789.1 - 0.28 11.1 0.1 0.28 11.1 0.1 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain Glucos_trans_II PF14264.6 CDS28789.1 - 0.41 10.0 13.0 1.9 7.8 13.0 1.7 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF2070 PF09843.9 CDS28789.1 - 0.64 8.2 4.5 0.74 8.0 4.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Presenilin PF01080.17 CDS28789.1 - 0.68 8.6 11.1 0.98 8.1 11.1 1.1 1 0 0 1 1 1 0 Presenilin Tetraspanin PF00335.20 CDS28789.1 - 1 9.0 9.2 1.4 8.5 9.2 1.2 1 0 0 1 1 1 0 Tetraspanin family YfhO PF09586.10 CDS28789.1 - 1.2 7.2 5.9 1.6 6.9 5.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 7TMR-DISM_7TM PF07695.11 CDS28789.1 - 1.6 8.6 16.9 3.9 7.3 16.9 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF2142 PF09913.9 CDS28789.1 - 8.1 5.2 13.4 12 4.6 13.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF3792 PF12670.7 CDS28789.1 - 9.8 6.4 16.0 1.8 8.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) MENTAL PF10457.9 CDS28790.1 - 2.3e-33 115.5 7.1 3.3e-33 115.0 7.1 1.2 1 0 0 1 1 1 1 Cholesterol-capturing domain START PF01852.19 CDS28790.1 - 1.6e-19 70.2 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 START domain Ras PF00071.22 CDS28791.1 - 2.9e-49 166.8 0.1 7.6e-49 165.4 0.1 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS28791.1 - 3.5e-29 101.5 0.7 6.8e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS28791.1 - 7.8e-13 48.2 1.0 1.6e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_7 PF13499.6 CDS28791.1 - 3.2e-07 30.7 0.2 3.2e-07 30.7 0.2 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS28791.1 - 1.3e-05 24.8 0.2 0.076 13.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.23 CDS28791.1 - 1.4e-05 25.2 1.6 2.5e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS28791.1 - 2.6e-05 23.9 0.0 2.6e-05 23.9 0.0 2.8 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.32 CDS28791.1 - 0.0023 17.4 0.1 1 9.1 0.0 3.0 2 0 0 2 2 2 1 EF hand FeoB_N PF02421.18 CDS28791.1 - 0.069 12.7 0.1 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Wtap PF17098.5 CDS28791.1 - 0.085 12.8 26.5 0.039 13.9 17.7 3.4 1 1 1 2 2 2 0 WTAP/Mum2p family YdiH PF15930.5 CDS28791.1 - 0.15 12.3 1.3 0.48 10.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF4407 PF14362.6 CDS28791.1 - 0.62 9.4 19.7 1.1 8.5 19.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 CDS28791.1 - 1.3 6.5 34.6 2.7 5.4 34.7 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Yip1 PF04893.17 CDS28792.1 - 9.7e-10 38.4 20.2 2.5e-09 37.1 20.2 1.6 1 1 0 1 1 1 1 Yip1 domain DUF3464 PF11947.8 CDS28792.1 - 5.1 6.8 5.1 6 6.6 4.5 1.4 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 RTP1_C1 PF10363.9 CDS28793.1 - 1.6e-30 105.5 0.8 1.1e-28 99.6 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CDS28793.1 - 3.5e-08 33.7 0.0 0.0075 16.6 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 CDS28793.1 - 2.2e-05 24.3 0.1 0.27 11.6 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 CDS28793.1 - 0.00027 19.7 0.3 0.093 11.3 0.0 3.1 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CDS28793.1 - 0.042 14.4 0.3 0.57 10.8 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Peptidase_C14 PF00656.22 CDS28794.1 - 1.5e-43 149.6 0.0 1.8e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.26 CDS28795.1 - 8.8e-22 76.3 45.3 0.00012 22.3 0.7 10.2 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28795.1 - 3.8e-20 70.8 48.8 0.00021 21.9 1.6 10.1 10 0 0 10 10 10 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS28795.1 - 8.5e-09 35.4 8.2 0.00041 20.7 0.8 8.2 9 1 0 9 9 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS28795.1 - 4.1e-05 23.7 18.1 1.3 9.4 0.2 6.8 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS28795.1 - 0.0007 19.5 7.7 0.0093 16.0 0.8 7.4 8 0 0 8 8 8 3 C2H2-type zinc finger HypA PF01155.19 CDS28795.1 - 0.0015 18.5 15.9 0.034 14.2 0.2 3.8 2 1 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3rep PF18868.1 CDS28795.1 - 0.017 15.8 15.0 3.5 8.3 3.5 4.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 CDS28795.1 - 0.028 14.0 18.1 1.6 8.4 0.1 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 CDS28795.1 - 0.063 13.7 1.2 0.063 13.7 1.2 6.0 4 3 2 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_Tnp_IS1595 PF12760.7 CDS28795.1 - 0.067 13.2 0.9 0.067 13.2 0.9 4.9 5 0 0 5 5 5 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDS28795.1 - 0.088 12.9 19.2 1.2 9.4 1.4 4.9 4 1 0 4 4 4 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 CDS28795.1 - 0.41 10.6 20.1 0.7 9.8 0.4 4.5 3 3 0 3 3 3 0 SprT-like zinc ribbon domain DUF3268 PF11672.8 CDS28795.1 - 0.42 11.0 10.7 12 6.2 0.4 4.2 2 2 2 4 4 4 0 zinc-finger-containing domain Actin_micro PF17003.5 CDS28795.1 - 0.68 9.1 12.2 0.85 8.7 1.1 3.3 2 2 2 4 4 4 0 Putative actin-like family FOXP-CC PF16159.5 CDS28795.1 - 0.68 10.6 11.5 8.5 7.1 0.2 4.1 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 CDS28795.1 - 1.2 9.6 15.2 3.7 8.1 0.2 5.9 7 0 0 7 7 5 0 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.12 CDS28795.1 - 1.3 8.6 13.4 8.3 6.0 0.0 4.7 4 1 0 4 4 4 0 TFIIB zinc-binding zf_C2H2_10 PF18414.1 CDS28795.1 - 1.4 8.5 15.2 11 5.7 0.3 5.1 5 0 0 5 5 5 0 C2H2 type zinc-finger DZR PF12773.7 CDS28795.1 - 2.3 8.3 23.8 1.2 9.2 2.0 4.4 2 2 0 2 2 1 0 Double zinc ribbon zf-BED PF02892.15 CDS28795.1 - 3.1 7.9 28.9 0.29 11.2 1.7 5.4 5 1 1 6 6 6 0 BED zinc finger PhnA_Zn_Ribbon PF08274.12 CDS28795.1 - 3.2 7.8 15.0 7.7 6.6 0.0 4.9 4 1 0 4 4 4 0 PhnA Zinc-Ribbon zf-CSL PF05207.13 CDS28795.1 - 3.5 7.4 9.1 6.4 6.6 0.2 3.5 3 0 0 3 3 3 0 CSL zinc finger DUF5472 PF17566.2 CDS28795.1 - 4.3 7.4 6.2 6.6 6.8 0.2 3.3 4 0 0 4 4 3 0 Family of unknown function (DUF5472) Anti-TRAP PF15777.5 CDS28795.1 - 4.8 7.2 8.6 1.4 9.0 0.3 3.8 4 0 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 CDS28795.1 - 8 6.9 15.3 17 5.9 4.2 4.5 2 1 3 5 5 4 0 Restriction alleviation protein Lar zf-HIT PF04438.16 CDS28795.1 - 9.2 6.2 20.2 18 5.3 0.3 5.9 6 0 0 6 6 6 0 HIT zinc finger PDZ PF00595.24 CDS28796.2 - 8.4e-58 192.7 0.7 2.6e-14 53.3 0.0 5.5 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 CDS28796.2 - 8.4e-36 121.6 8.3 6.1e-08 32.4 0.9 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 CDS28796.2 - 3.2e-23 81.8 0.0 0.0012 19.1 0.0 5.4 5 0 0 5 5 5 5 PDZ domain Guanylate_kin PF00625.21 CDS28796.2 - 1.4e-08 34.7 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase WW PF00397.26 CDS28796.2 - 0.00017 21.6 0.6 0.00033 20.7 0.6 1.5 1 0 0 1 1 1 1 WW domain PDZ_4 PF17816.1 CDS28796.2 - 0.12 12.7 0.0 40 4.7 0.0 3.2 4 0 0 4 4 4 0 PDZ domain Pkinase PF00069.25 CDS28797.2 - 5.5e-50 170.2 0.0 1.1e-49 169.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28797.2 - 1.2e-24 87.0 0.0 2.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIC3 PF15361.6 CDS28797.2 - 1.2e-12 48.4 3.3 2.1e-12 47.6 0.3 3.0 2 1 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 RIO1 PF01163.22 CDS28797.2 - 0.0038 16.8 0.1 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDS28797.2 - 0.0041 17.1 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS28797.2 - 0.07 12.5 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDS28797.2 - 0.11 12.2 0.1 14 5.3 0.0 2.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Methyltransf_10 PF05971.12 CDS28799.2 - 6.9e-19 68.3 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Herpes_UL56 PF04534.12 CDS28800.1 - 6 6.3 5.5 9.7 5.6 5.5 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Hyccin PF09790.9 CDS28802.2 - 0.057 12.5 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Hyccin C2 PF00168.30 CDS28804.1 - 7.2e-19 68.0 0.0 1.4e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain FYVE_2 PF02318.16 CDS28804.1 - 7.1e-11 42.4 9.2 1.8e-10 41.1 9.2 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger PDZ PF00595.24 CDS28804.1 - 5.5e-05 23.4 0.1 0.00014 22.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS28804.1 - 0.0016 18.2 0.1 0.0043 16.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Sec20 PF03908.13 CDS28805.1 - 1.4e-10 40.9 0.9 2.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 CDS28805.1 - 0.04 13.3 0.2 0.058 12.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF327 PF03885.13 CDS28805.1 - 0.042 13.8 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Rubrerythrin PF02915.17 CDS28805.1 - 0.087 13.2 0.1 0.47 10.9 0.0 2.0 2 0 0 2 2 2 0 Rubrerythrin DUF4704 PF15787.5 CDS28806.1 - 2.1e-06 27.2 0.2 2.6e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) 7tm_1 PF00001.21 CDS28807.1 - 7.7e-10 38.5 11.1 7.7e-10 38.5 11.1 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS28807.1 - 0.024 14.3 22.8 0.015 14.9 20.6 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx adh_short PF00106.25 CDS28810.1 - 1.6e-17 63.6 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDS28810.1 - 7.4e-10 38.8 0.0 1e-09 38.3 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Paz_1 PF18349.1 CDS28810.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PAZ domain Lentiviral_Tat PF02998.14 CDS28810.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Lentiviral Tat protein MRP-L47 PF06984.13 CDS28811.1 - 1.8e-33 114.5 2.2 1.8e-33 114.5 2.2 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pkinase PF00069.25 CDS28812.2 - 7.5e-77 258.2 0.0 1.1e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28812.2 - 1.8e-45 155.2 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CDS28812.2 - 4.7e-17 61.5 0.0 8.3e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CDS28812.2 - 4.5e-08 32.8 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS28812.2 - 0.0014 18.0 0.1 0.0031 16.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS28812.2 - 0.0075 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA PF00627.31 CDS28812.2 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Haspin_kinase PF12330.8 CDS28812.2 - 0.091 11.7 1.5 0.092 11.7 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain SelP_N PF04592.14 CDS28812.2 - 1.3 8.4 5.5 3.2 7.1 5.5 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region tRNA-synt_1 PF00133.22 CDS28813.1 - 1.8e-112 376.6 0.0 2.3e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDS28813.1 - 1.5e-08 34.7 0.0 2.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDS28813.1 - 5.3e-06 25.4 10.7 0.0065 15.3 0.2 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDS28813.1 - 1.3e-05 24.9 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CDS28813.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CDS28813.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DED PF01335.21 CDS28814.1 - 0.0029 17.9 0.0 0.0086 16.4 0.0 1.8 1 0 0 1 1 1 1 Death effector domain Histone PF00125.24 CDS28815.1 - 6.8e-52 175.3 3.4 7.6e-52 175.1 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDS28815.1 - 0.00014 22.1 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDS28815.1 - 0.0003 20.9 0.1 0.00056 20.0 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDS28815.1 - 0.00035 21.2 1.3 0.00041 20.9 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CDS28815.1 - 0.025 14.9 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS28816.1 - 3.9e-53 179.3 2.7 4.3e-53 179.1 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS28816.1 - 7.6e-05 22.8 0.3 0.00013 22.0 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CDS28816.1 - 0.00015 22.3 1.1 0.00016 22.2 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CDS28816.1 - 0.00031 21.1 0.0 0.00048 20.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDS28816.1 - 0.049 13.9 0.1 0.098 13.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS28816.1 - 0.078 13.1 0.1 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CDS28818.1 - 1.4e-49 167.8 4.9 1.5e-49 167.7 4.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDS28818.1 - 1.7e-05 25.1 0.1 3.9e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 CDS28818.1 - 0.00015 21.8 0.7 0.00062 19.9 0.1 1.9 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CDS28818.1 - 0.0013 19.0 0.6 0.0031 17.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 CDS28818.1 - 0.003 18.1 0.2 0.0031 18.1 0.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 CDS28818.1 - 0.028 14.5 0.1 0.057 13.5 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDS28818.1 - 0.061 13.3 0.4 0.098 12.7 0.0 1.6 2 0 0 2 2 2 0 Bromodomain associated FGGY_N PF00370.21 CDS28819.1 - 4e-07 29.9 0.0 0.0074 15.9 0.0 2.9 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain ig PF00047.25 CDS28820.1 - 8.5e-06 25.9 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS28820.1 - 0.002 18.1 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.17 CDS28820.1 - 0.0025 18.0 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 CDS28820.1 - 0.041 14.5 0.0 0.057 14.0 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Ig_6 PF18452.1 CDS28820.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Helicase_C_2 PF13307.6 CDS28821.2 - 1.5e-51 174.9 0.1 5.2e-51 173.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDS28821.2 - 1e-37 129.5 0.9 7.3e-37 126.7 0.9 2.3 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CDS28821.2 - 3e-06 27.3 0.1 7.5e-05 22.8 0.1 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 CDS28821.2 - 0.00017 21.4 10.7 0.00017 21.4 10.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CDS28821.2 - 0.00018 21.3 0.0 0.005 16.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 CDS28821.2 - 0.00092 19.0 11.1 0.00092 19.0 11.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS28821.2 - 0.0013 18.5 9.1 0.0036 17.1 9.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PhoH PF02562.16 CDS28821.2 - 0.0016 17.9 0.0 0.44 10.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein zf-RING_2 PF13639.6 CDS28821.2 - 0.0089 16.3 11.0 0.026 14.8 11.0 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDS28821.2 - 0.023 14.6 9.5 0.066 13.1 9.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDS28821.2 - 0.034 14.1 10.2 0.086 12.8 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CDS28821.2 - 0.22 11.3 13.6 1.2 9.0 13.8 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 CDS28821.2 - 0.26 11.4 4.9 0.87 9.7 4.9 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger GTP_EFTU PF00009.27 CDS28822.1 - 5.1e-43 146.9 0.1 1e-42 145.9 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDS28822.1 - 2.3e-10 40.8 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CDS28822.1 - 3.8e-06 27.0 0.0 0.044 13.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GBP PF02263.19 CDS28822.1 - 0.13 11.5 0.2 0.24 10.6 0.0 1.4 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.6 CDS28822.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDS28822.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Innexin PF00876.18 CDS28824.1 - 6e-05 22.5 0.2 0.0001 21.7 0.2 1.3 1 0 0 1 1 1 1 Innexin PRA1 PF03208.19 CDS28824.1 - 1.2 8.8 10.3 0.47 10.1 5.4 2.4 2 0 0 2 2 2 0 PRA1 family protein CUB PF00431.20 CDS28826.2 - 2.3e-128 420.6 6.8 1.3e-36 125.3 0.1 6.3 6 1 0 6 6 6 5 CUB domain Astacin PF01400.24 CDS28826.2 - 1e-69 234.0 0.0 2.5e-69 232.7 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.6 CDS28826.2 - 2.9e-20 72.2 26.1 4.2e-10 39.7 9.9 2.9 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CDS28826.2 - 1.1e-16 60.7 25.0 1.6e-08 34.6 8.2 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 CDS28826.2 - 1.5e-09 37.6 10.9 4.1e-06 26.6 0.8 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 CDS28826.2 - 3e-08 33.8 24.0 0.00059 20.1 6.2 3.0 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.20 CDS28826.2 - 9.5e-07 28.6 6.0 0.011 15.4 0.1 4.6 4 0 0 4 4 4 2 CUB-like domain EGF_3 PF12947.7 CDS28826.2 - 0.00045 20.4 33.4 0.0068 16.6 11.1 3.3 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 CDS28826.2 - 0.001 19.6 18.3 0.13 12.9 3.0 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Peptidase_M10 PF00413.24 CDS28826.2 - 0.014 15.3 0.3 2.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Matrixin DUF3659 PF12396.8 CDS28826.2 - 0.16 11.9 0.3 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Noelin-1 PF12308.8 CDS28826.2 - 0.51 10.3 6.8 0.56 10.2 4.8 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein EGF_MSP1_1 PF12946.7 CDS28826.2 - 1.6 8.8 15.4 0.58 10.2 1.3 2.9 2 0 0 2 2 2 0 MSP1 EGF domain 1 DASH_Dad3 PF08656.10 CDS28826.2 - 4.9 7.3 6.9 17 5.6 5.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 FAR1 PF03101.15 CDS28829.1 - 0.0062 17.2 0.9 0.0062 17.2 0.9 2.9 3 1 0 3 3 3 2 FAR1 DNA-binding domain FLYWCH PF04500.16 CDS28829.1 - 0.013 15.6 11.2 0.65 10.2 2.6 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain Transposase_1 PF01359.18 CDS28831.1 - 9e-05 22.2 0.2 0.00021 21.1 0.0 1.6 2 0 0 2 2 2 1 Transposase (partial DDE domain) zf-RING_2 PF13639.6 CDS28832.1 - 4.7e-09 36.4 24.4 1.9e-06 28.1 7.8 4.1 3 1 1 4 4 4 2 Ring finger domain Zn_ribbon_17 PF17120.5 CDS28832.1 - 1e-06 28.2 7.4 1e-06 28.2 7.4 3.5 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CDS28832.1 - 1.3e-06 28.2 25.6 1.4e-05 24.9 9.9 4.2 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS28832.1 - 1.2e-05 25.4 6.8 1.2e-05 25.4 6.8 4.0 3 2 1 4 4 4 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDS28832.1 - 0.00031 20.5 9.3 0.00031 20.5 9.3 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDS28832.1 - 0.00056 19.9 4.3 0.00056 19.9 4.3 3.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CDS28832.1 - 0.0062 16.4 7.6 0.0062 16.4 7.6 4.5 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS28832.1 - 0.023 14.7 8.1 0.023 14.7 8.1 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 CDS28832.1 - 0.03 14.3 6.5 0.03 14.3 6.5 5.1 4 1 0 4 4 4 0 zinc-RING finger domain RINGv PF12906.7 CDS28832.1 - 0.048 13.8 5.5 0.048 13.8 5.5 4.2 4 2 0 4 4 4 0 RING-variant domain Homeodomain PF00046.29 CDS28833.1 - 8.4e-23 80.0 3.9 1.5e-22 79.1 3.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS28833.1 - 0.0066 16.3 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDS28833.1 - 0.063 12.8 0.4 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.25 CDS28834.2 - 3.7e-55 187.1 0.1 5.2e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28834.2 - 6.5e-23 81.3 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS28834.2 - 0.0019 17.6 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS28834.2 - 0.0022 16.8 0.1 0.0035 16.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS28834.2 - 0.0026 17.7 0.1 0.0038 17.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Spa1_C PF18218.1 CDS28834.2 - 0.037 14.4 0.3 17 5.9 0.0 3.5 3 1 1 4 4 4 0 Lantibiotic immunity protein Spa1 C-terminal domain Pribosyltran PF00156.27 CDS28835.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2992 PF11208.8 CDS28836.1 - 0.092 13.0 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Alkyl_sulf_dimr PF14863.6 CDS28836.1 - 0.094 13.2 0.0 0.15 12.5 0.0 1.3 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_19 PF14559.6 CDS28836.1 - 0.095 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS28836.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat SNF2_N PF00176.23 CDS28837.2 - 1.9e-58 197.9 0.4 4.1e-58 196.8 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS28837.2 - 9e-16 58.2 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS28837.2 - 6.1e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDS28837.2 - 6.2e-08 32.1 0.0 2e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.10 CDS28837.2 - 1.8e-07 31.5 0.1 4.1e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 Rad54 N terminal AAA_22 PF13401.6 CDS28837.2 - 0.048 13.9 0.0 1.7 8.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain CD34_antigen PF06365.12 CDS28838.2 - 0.14 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family FAM163 PF15069.6 CDS28839.1 - 0.037 14.5 0.0 0.037 14.5 0.0 1.5 2 0 0 2 2 2 0 FAM163 family Mid2 PF04478.12 CDS28839.1 - 0.04 13.7 0.5 0.066 13.0 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Phage_Coat_B PF05356.11 CDS28839.1 - 3 7.8 5.9 1.1 9.2 3.3 1.6 1 1 1 2 2 2 0 Phage Coat protein B Sugar_tr PF00083.24 CDS28841.1 - 1e-21 77.4 14.6 1.6e-21 76.7 14.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS28841.1 - 1.4e-11 44.0 21.2 1.4e-11 44.0 21.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CP2 PF04516.15 CDS28842.1 - 7.1e-45 153.1 0.6 1.2e-43 149.1 0.0 2.3 2 0 0 2 2 2 1 CP2 transcription factor SAM_3 PF18016.1 CDS28842.1 - 8.6e-09 35.1 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CDS28843.2 - 1.6e-19 69.5 0.1 3.1e-09 36.5 0.0 3.0 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CDS28843.2 - 1.8e-18 65.9 0.0 9.5e-10 38.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDS28843.2 - 7.9e-13 47.8 0.0 5.9e-05 22.6 0.0 2.9 2 0 0 2 2 2 2 SH3 domain fn3 PF00041.21 CDS28843.2 - 4e-08 33.5 2.5 0.064 13.6 0.0 4.4 3 1 0 3 3 3 2 Fibronectin type III domain ICL PF00463.21 CDS28843.2 - 0.045 12.3 0.0 0.07 11.6 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family DUF977 PF06163.11 CDS28843.2 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) WD40 PF00400.32 CDS28844.1 - 5.5e-36 122.0 29.5 2.6e-08 34.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28844.1 - 9.5e-13 48.3 0.1 0.22 11.9 0.0 5.8 2 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS28844.1 - 0.00015 21.7 0.0 2.3 8.1 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDS28844.1 - 0.0002 20.8 0.0 0.024 14.0 0.0 3.3 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CDS28844.1 - 0.0025 16.8 0.1 1.9 7.3 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CDS28845.1 - 2.7e-60 198.9 23.9 5.4e-09 36.5 0.3 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28845.1 - 9e-18 64.4 0.6 0.001 19.3 0.1 5.3 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS28845.1 - 3.9e-08 32.4 5.8 0.13 10.9 0.1 5.1 2 2 3 5 5 5 4 Nucleoporin Nup120/160 LisH PF08513.11 CDS28845.1 - 9.1e-05 22.3 0.5 0.00022 21.1 0.5 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 CDS28845.1 - 0.00033 19.5 0.1 0.09 11.5 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like LisH_2 PF16045.5 CDS28845.1 - 0.0059 15.6 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 CDS28845.1 - 0.028 13.4 4.2 0.21 10.5 1.0 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Colicin_K PF17500.2 CDS28846.1 - 0.0036 17.8 0.3 0.0053 17.3 0.3 1.3 1 1 0 1 1 1 1 Colicin-K LapA_dom PF06305.11 CDS28846.1 - 0.018 14.8 0.5 0.027 14.3 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pex24p PF06398.11 CDS28846.1 - 0.11 11.4 0.9 0.12 11.3 0.9 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RseC_MucC PF04246.12 CDS28846.1 - 0.11 12.4 6.0 0.11 12.4 1.1 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LRR_8 PF13855.6 CDS28848.2 - 2e-16 59.5 25.7 5.4e-07 29.3 0.3 4.9 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CDS28848.2 - 1.1e-14 54.3 37.9 0.00018 21.8 1.2 6.0 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS28848.2 - 5.7e-06 26.0 8.6 0.0049 16.4 2.6 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CDS28848.2 - 0.0012 19.1 25.8 0.11 13.1 3.3 7.0 6 2 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 CDS28848.2 - 0.32 11.2 23.4 0.41 10.8 0.1 6.5 7 0 0 7 7 7 0 Leucine Rich repeat Ndr PF03096.14 CDS28849.1 - 2.5e-74 249.5 0.0 3.1e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 CDS28849.1 - 0.0026 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDS28849.1 - 0.0052 17.4 0.0 0.006 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDS28849.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold bZIP_1 PF00170.21 CDS28850.1 - 0.0031 17.6 1.1 0.007 16.4 1.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDS28850.1 - 0.018 15.1 1.1 0.042 13.9 1.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper WD40 PF00400.32 CDS28851.1 - 8.6e-39 130.9 23.8 3.3e-07 30.9 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS28851.1 - 1.4e-15 57.3 1.0 0.014 15.7 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS28851.1 - 5.4e-05 22.3 1.3 0.033 13.1 0.0 3.7 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS28851.1 - 0.0038 17.1 0.4 0.84 9.5 0.1 3.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CDS28851.1 - 0.17 10.9 0.1 1.2 8.1 0.1 2.3 3 0 0 3 3 3 0 Coatomer WD associated region WD40 PF00400.32 CDS28852.1 - 3.2e-39 132.2 19.4 8.7e-07 29.6 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 CDS28852.1 - 3.8e-18 65.1 1.3 7.2e-18 64.2 1.3 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.7 CDS28852.1 - 7.7e-08 32.1 0.3 2.4e-07 30.5 0.3 1.9 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 CDS28852.1 - 1.8e-05 24.2 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CDS28852.1 - 2e-05 23.5 1.0 1.3 7.6 0.1 3.7 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDS28852.1 - 2.1e-05 24.7 1.9 0.0077 16.5 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CDS28852.1 - 0.00041 20.2 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 CDS28852.1 - 0.0018 18.3 0.0 2.7 8.1 0.0 3.8 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF1513 PF07433.11 CDS28852.1 - 0.013 14.7 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF2066 PF09839.9 CDS28852.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Cytochrom_B561 PF03188.16 CDS28854.1 - 5e-40 136.8 10.6 1.1e-39 135.7 10.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1129 PF06570.11 CDS28854.1 - 2.5 7.6 7.4 5.8 6.3 2.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) Ni_hydr_CYTB PF01292.20 CDS28854.1 - 3.1 7.3 19.2 0.15 11.6 11.3 2.6 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 Methyltransf_8 PF05148.15 CDS28855.1 - 6.8e-66 222.3 0.1 1.1e-65 221.6 0.1 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Pkinase_Tyr PF07714.17 CDS28855.1 - 7.3e-36 123.8 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CDS28855.1 - 1.4e-31 108.9 7.2 2.4e-17 63.3 0.7 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Pkinase PF00069.25 CDS28855.1 - 1.3e-22 80.5 0.0 6.2e-22 78.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 CDS28855.1 - 8.5e-20 70.6 9.3 8.6e-10 38.7 2.2 4.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS28855.1 - 3.1e-17 62.2 1.1 7.5e-07 29.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CDS28855.1 - 3.1e-17 62.7 1.2 1.9e-09 37.9 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS28855.1 - 3.4e-16 57.7 3.7 3.9e-05 23.7 0.1 4.7 5 0 0 5 5 4 3 Ankyrin repeat Methyltransf_11 PF08241.12 CDS28855.1 - 2.7e-05 24.8 0.1 0.00012 22.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS28855.1 - 0.00025 21.7 0.5 0.095 13.4 0.1 4.0 3 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CDS28855.1 - 0.019 14.5 0.1 4.3 6.9 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 CDS28855.1 - 0.14 11.9 0.2 1.4 8.7 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain EF1_GNE PF00736.19 CDS28856.1 - 1.7e-33 114.7 1.0 2.6e-33 114.0 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CDS28856.1 - 0.00047 20.6 1.8 0.00047 20.6 1.8 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Sel1 PF08238.12 CDS28857.1 - 5.6e-06 26.9 0.7 1.3 9.8 0.1 3.8 3 0 0 3 3 3 3 Sel1 repeat Sedlin_N PF04628.13 CDS28858.1 - 1.3e-19 70.7 0.0 1.5e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DnaJ PF00226.31 CDS28859.1 - 8.3e-10 38.7 0.4 8.3e-10 38.7 0.4 2.7 2 1 0 2 2 2 1 DnaJ domain ARL2_Bind_BART PF11527.8 CDS28859.1 - 0.36 10.9 3.9 3 8.0 3.9 2.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART SH2 PF00017.24 CDS28860.2 - 7.1e-07 29.2 3.0 0.033 14.3 0.1 3.1 3 0 0 3 3 3 2 SH2 domain PH PF00169.29 CDS28860.2 - 3.7e-05 24.2 0.1 0.00024 21.6 0.0 2.2 2 0 0 2 2 2 1 PH domain Hormone_6 PF00236.18 CDS28860.2 - 0.00029 20.8 2.4 0.74 9.8 0.2 2.7 2 0 0 2 2 2 2 Glycoprotein hormone SH3_9 PF14604.6 CDS28860.2 - 0.0005 19.9 0.2 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain RasGAP PF00616.19 CDS28860.2 - 0.0055 16.4 0.0 0.98 9.1 0.0 2.3 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase Pro-MCH PF05824.12 CDS28860.2 - 0.021 14.7 1.2 7.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) SH3_2 PF07653.17 CDS28860.2 - 0.029 14.0 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain PAC1 PF16094.5 CDS28860.2 - 0.097 11.8 0.6 16 4.6 0.1 2.6 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 zf-CW PF07496.15 CDS28861.1 - 9.3e-05 22.4 6.2 0.00019 21.4 5.2 2.2 2 0 0 2 2 2 1 CW-type Zinc Finger Kri1_C PF12936.7 CDS28862.1 - 3.4e-28 97.6 0.4 3.4e-28 97.6 0.4 3.2 2 0 0 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.12 CDS28862.1 - 1.1e-20 74.1 7.6 1.1e-20 74.1 7.6 5.9 4 2 2 6 6 6 1 KRI1-like family Transglut_core PF01841.19 CDS28862.1 - 5.2e-05 23.7 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Med7 PF05983.11 CDS28871.2 - 0.47 10.5 7.4 1.2 9.1 7.4 1.7 1 0 0 1 1 1 0 MED7 protein zf-C2H2_4 PF13894.6 CDS28871.2 - 5.6 8.1 9.5 0.62 11.1 3.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS28876.2 - 0.0052 17.2 0.9 0.0052 17.2 0.9 4.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS28876.2 - 0.22 12.0 9.1 0.049 14.1 3.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Mito_carr PF00153.27 CDS28877.2 - 3.6e-39 132.6 0.6 3.9e-12 45.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_49kDa PF00346.19 CDS28878.1 - 4.7e-118 393.2 0.0 8.9e-118 392.3 0.0 1.4 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CDS28878.1 - 0.015 14.2 0.0 0.087 11.7 0.0 1.9 2 0 0 2 2 2 0 Nickel-dependent hydrogenase ATP-synt_ab PF00006.25 CDS28879.1 - 3e-73 246.0 0.0 4.7e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CDS28879.1 - 5.8e-49 165.6 1.1 1.2e-48 164.6 0.9 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CDS28879.1 - 5.7e-18 65.2 0.9 1.5e-17 63.9 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CDS28879.1 - 0.14 12.3 0.9 0.77 9.9 0.4 2.4 2 1 1 3 3 3 0 HAS barrel domain Mito_carr PF00153.27 CDS28880.1 - 4e-13 49.1 1.0 1.3e-07 31.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein PIG-F PF06699.11 CDS28880.1 - 0.074 13.2 0.0 0.091 12.9 0.0 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Transposase_1 PF01359.18 CDS28882.1 - 9.9e-10 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) Cucumo_2B PF03263.13 CDS28883.1 - 3.1 8.3 8.1 1 9.8 1.7 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B YhfH PF14149.6 CDS28884.1 - 0.057 13.4 0.8 0.11 12.5 0.8 1.4 1 0 0 1 1 1 0 YhfH-like protein zinc_ribbon_4 PF13717.6 CDS28884.1 - 0.063 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDS28884.1 - 0.14 12.3 0.3 0.14 12.3 0.3 1.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF4141 PF13605.6 CDS28884.1 - 0.16 11.2 0.6 0.24 10.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) NMT_C PF02799.15 CDS28886.1 - 1.1e-74 250.5 0.0 1.5e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CDS28886.1 - 6.3e-74 247.1 0.0 3.7e-72 241.4 0.0 2.3 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CDS28886.1 - 0.00033 20.7 0.0 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDS28886.1 - 0.00039 20.6 0.5 0.0085 16.3 0.0 3.1 3 1 1 4 4 4 1 Acetyltransferase (GNAT) family Cnl2_NKP2 PF09447.10 CDS28886.1 - 0.082 13.1 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Cnl2/NKP2 family protein DUF508 PF04370.12 CDS28886.1 - 4 7.2 6.5 27 4.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) WD40 PF00400.32 CDS28887.1 - 5.7e-28 96.6 26.2 1.1e-05 26.1 0.0 9.0 9 1 0 9 9 9 6 WD domain, G-beta repeat PQQ_3 PF13570.6 CDS28887.1 - 9.4e-08 32.3 0.1 0.039 14.5 0.0 5.2 6 0 0 6 6 6 2 PQQ-like domain ANAPC4_WD40 PF12894.7 CDS28887.1 - 3.9e-07 30.3 0.1 0.49 10.7 0.1 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDS28887.1 - 0.00024 20.8 0.1 0.0033 17.0 0.1 2.7 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.11 CDS28887.1 - 0.00078 18.3 0.0 0.04 12.7 0.0 3.3 4 0 0 4 4 4 1 Nup133 N terminal like DUF2844 PF11005.8 CDS28887.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) WD40_like PF17005.5 CDS28887.1 - 0.089 12.1 0.3 0.9 8.8 0.2 2.3 2 1 0 2 2 2 0 WD40-like domain Hyccin PF09790.9 CDS28888.1 - 6.5e-25 87.9 1.2 4.2e-11 42.5 0.1 3.5 3 0 0 3 3 3 3 Hyccin Pkinase PF00069.25 CDS28889.1 - 7.2e-55 186.2 0.0 1.5e-37 129.4 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28889.1 - 2.6e-27 95.8 0.1 1.4e-21 77.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS28889.1 - 0.00084 18.7 0.1 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDS28889.1 - 0.0026 17.7 0.1 0.046 13.6 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS28889.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS28889.1 - 0.079 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 CDS28890.1 - 1.4e-24 85.7 2.2 2.9e-19 68.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 CDS28890.1 - 7.2e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 CDS28890.1 - 0.004 17.2 0.1 0.039 14.0 0.0 2.4 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 CDS28890.1 - 0.029 14.4 0.0 0.55 10.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF4597 PF15366.6 CDS28890.1 - 0.038 13.7 0.2 0.15 11.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) zf-C2H2 PF00096.26 CDS28891.1 - 2.3e-16 59.2 28.1 0.00054 20.3 0.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS28891.1 - 1e-14 54.1 23.8 1.7e-07 31.3 0.5 5.2 5 0 0 5 5 5 3 Zinc-finger double domain FOXP-CC PF16159.5 CDS28891.1 - 1.1e-06 29.2 14.9 0.0065 17.1 4.8 4.6 2 2 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDS28891.1 - 7.7e-06 26.3 26.9 0.0088 16.8 0.6 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CDS28891.1 - 0.0027 17.9 14.3 0.02 15.1 1.4 3.9 2 1 1 3 3 3 2 Aberrant zinc-finger zf_ZIC PF18366.1 CDS28891.1 - 0.018 15.1 3.0 0.2 11.8 0.1 3.3 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 CDS28891.1 - 4.2 7.5 10.9 0.48 10.5 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDS28891.1 - 5.3 7.4 9.6 2.1 8.7 0.8 3.1 1 1 0 2 2 2 0 C2H2-type zinc ribbon Acyltransferase PF01553.21 CDS28895.1 - 1.3e-30 105.8 0.0 1.5e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Phage_holin_7_1 PF16081.5 CDS28896.1 - 0.51 10.5 7.9 0.93 9.7 7.9 1.5 1 1 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF5373 PF17343.2 CDS28896.1 - 6.1 6.7 12.9 9.8 6.0 12.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF2070 PF09843.9 CDS28896.1 - 8.2 4.6 17.0 9.7 4.3 17.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CD20 PF04103.15 CDS28897.1 - 0.0028 17.8 11.8 0.0043 17.1 11.8 1.3 1 0 0 1 1 1 1 CD20-like family RCDG1 PF15725.5 CDS28897.1 - 1.8 9.0 6.0 3.5 8.1 6.0 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF2070 PF09843.9 CDS28897.1 - 9 4.4 11.3 12 4.1 11.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_U4 PF03419.13 CDS28898.1 - 0.00085 18.7 9.4 0.0011 18.3 9.4 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA CD20 PF04103.15 CDS28898.1 - 0.12 12.4 11.5 0.035 14.2 8.4 1.5 1 1 0 1 1 1 0 CD20-like family CSN8_PSD8_EIF3K PF10075.9 CDS28900.1 - 5.8e-14 52.3 0.0 7.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RhoGAP PF00620.27 CDS28901.1 - 2.9e-41 140.8 0.0 4.5e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SH2 PF00017.24 CDS28901.1 - 6.6e-14 51.8 0.0 1.8e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.22 CDS28901.1 - 1.8e-13 50.1 7.5 3.4e-13 49.3 7.5 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDS28901.1 - 2.1 8.7 8.1 0.35 11.2 3.8 1.9 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 CDS28901.1 - 8.7 6.7 9.4 2.3 8.6 4.9 2.2 2 0 0 2 2 2 0 RING-like domain P5CR_dimer PF14748.6 CDS28903.1 - 2.1e-36 124.3 0.2 3.8e-36 123.4 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CDS28903.1 - 7.1e-14 52.2 0.1 1.5e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 CDS28903.1 - 0.02 13.9 0.2 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase HMG_box PF00505.19 CDS28905.1 - 6.6e-14 52.1 1.0 4.3e-13 49.5 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS28905.1 - 0.0029 18.2 0.1 0.0091 16.6 0.0 1.9 1 1 0 1 1 1 1 HMG-box domain STN1_2 PF09170.10 CDS28905.1 - 0.14 12.3 4.4 0.3 11.3 4.4 1.5 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF3810 PF12725.7 CDS28905.1 - 0.59 9.4 2.5 0.99 8.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Fcf1 PF04900.12 CDS28906.1 - 2.9e-31 107.8 3.1 2.9e-31 107.8 3.1 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CDS28906.1 - 3.4e-10 40.2 0.7 5.4e-10 39.6 0.1 1.6 2 0 0 2 2 2 1 PIN like domain DUF116 PF01976.17 CDS28906.1 - 0.0046 16.5 1.2 0.0078 15.7 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF116 TINF2_N PF14973.6 CDS28906.1 - 0.055 13.8 0.1 0.096 13.0 0.1 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Dynein_light PF01221.18 CDS28906.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 zf-HIT PF04438.16 CDS28907.1 - 3.7e-10 39.5 10.7 5.7e-10 38.9 10.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Homeodomain PF00046.29 CDS28909.1 - 2.2e-19 69.0 6.1 4.3e-19 68.1 6.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS28909.1 - 0.0072 16.2 0.2 0.021 14.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain TIMP PF00965.17 CDS28910.1 - 1e-08 35.2 1.8 7.5e-08 32.4 1.8 2.0 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase TMEM151 PF14857.6 CDS28911.1 - 2.7e-24 85.9 18.7 5.5e-23 81.6 18.7 2.4 1 1 0 1 1 1 1 TMEM151 family DUF4842 PF16130.5 CDS28911.1 - 0.02 15.1 0.3 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4842) Cation_ATPase_C PF00689.21 CDS28911.1 - 0.065 12.9 0.2 0.088 12.5 0.2 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus 7tm_1 PF00001.21 CDS28912.1 - 2.1e-18 66.6 11.2 2.5e-18 66.4 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SCAMP PF04144.13 CDS28912.1 - 0.002 18.5 0.2 0.002 18.5 0.2 3.1 4 0 0 4 4 4 1 SCAMP family 7TM_GPCR_Srz PF10325.9 CDS28912.1 - 0.42 9.9 17.0 0.027 13.8 8.7 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz Pox_I5 PF04713.12 CDS28912.1 - 0.53 10.4 4.4 2.4 8.3 0.0 3.4 3 0 0 3 3 3 0 Poxvirus protein I5 CHCH PF06747.13 CDS28916.1 - 1.7e-06 28.0 7.3 2.5e-06 27.4 7.3 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 CDS28916.1 - 0.049 14.0 4.1 0.08 13.3 4.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 CDS28916.1 - 0.064 13.3 4.6 0.16 12.0 1.3 2.2 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3734 PF12536.8 CDS28916.1 - 0.098 13.0 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Patatin phospholipase Spt4 PF06093.13 CDS28917.1 - 4.6e-29 100.3 0.1 5.6e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C4 PF00105.18 CDS28917.1 - 0.03 14.8 0.7 0.041 14.4 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Amidase PF01425.21 CDS28918.1 - 1.2e-104 350.8 0.0 1.6e-104 350.4 0.0 1.1 1 0 0 1 1 1 1 Amidase LSM PF01423.22 CDS28919.1 - 4.4e-15 55.1 0.0 6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDS28919.1 - 0.00042 20.4 0.3 0.0011 19.0 0.0 1.8 1 1 1 2 2 2 1 Ataxin 2 SM domain SHQ1 PF04925.15 CDS28920.1 - 0.022 14.4 0.4 0.042 13.4 0.4 1.4 1 0 0 1 1 1 0 SHQ1 protein 14-3-3 PF00244.20 CDS28921.1 - 5.8e-97 323.5 6.3 6.6e-97 323.4 6.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Cullin PF00888.22 CDS28922.1 - 3.2e-52 178.0 0.0 1.1e-50 172.9 0.0 2.3 1 1 1 2 2 2 2 Cullin family DUF4710 PF15828.5 CDS28923.2 - 0.0046 17.0 0.4 0.011 15.8 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4710) RWP-RK PF02042.15 CDS28923.2 - 0.13 12.3 0.1 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 RWP-RK domain Pkinase PF00069.25 CDS28924.2 - 2e-59 201.1 0.0 2.4e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS28924.2 - 6.3e-32 110.9 0.0 7.8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS28924.2 - 8.2e-05 22.0 0.0 0.00022 20.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDS28924.2 - 0.00083 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDS28924.2 - 0.003 17.2 0.5 2 8.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDS28924.2 - 0.033 13.1 0.2 0.3 10.0 0.2 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Abi_HHR PF07815.14 CDS28924.2 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Abl-interactor HHR Pkinase_fungal PF17667.1 CDS28924.2 - 0.072 11.8 0.2 0.17 10.6 0.0 1.6 1 1 0 2 2 2 0 Fungal protein kinase Mito_carr PF00153.27 CDS28925.1 - 1.2e-69 230.3 1.1 2.4e-23 81.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CDS28925.1 - 0.055 13.7 0.0 14 6.0 0.0 3.5 3 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Serine_protease PF18405.1 CDS28925.1 - 0.15 11.2 0.3 1.4 8.0 0.1 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Proteasome PF00227.26 CDS28926.1 - 1.6e-14 53.8 0.0 1.8e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4566 PF15130.6 CDS28926.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Proteasome PF00227.26 CDS28927.1 - 8.5e-10 38.4 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit NSP2-B_epitope PF14757.6 CDS28928.1 - 0.19 11.4 2.8 0.13 11.9 0.4 1.9 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Glyco_transf_43 PF03360.16 CDS28929.1 - 1.1e-60 205.0 0.0 1.3e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 RVT_1 PF00078.27 CDS28930.1 - 1.8e-10 40.7 0.1 8.3e-06 25.5 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltrn_RNA_3 PF02598.17 CDS28930.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase Innexin PF00876.18 CDS28931.1 - 5.4e-107 358.1 6.0 6.2e-107 357.9 6.0 1.0 1 0 0 1 1 1 1 Innexin Peptidase_M13_N PF05649.13 CDS28931.1 - 0.16 11.7 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M13 DDE_3 PF13358.6 CDS28932.1 - 0.07 12.9 0.2 0.075 12.8 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease XRN_N PF03159.18 CDS28934.1 - 4.6e-81 271.8 1.2 5.1e-81 271.7 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CDS28934.1 - 8.6e-69 232.6 0.1 3.9e-68 230.4 0.1 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN1_D1 PF18332.1 CDS28934.1 - 3.2e-11 43.3 0.2 2.1e-10 40.7 0.0 2.3 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CDS28934.1 - 8.7e-10 38.6 0.0 2.4e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain Guanylate_kin PF00625.21 CDS28936.1 - 1.9e-38 132.0 0.0 9.3e-38 129.7 0.0 2.0 2 0 0 2 2 2 1 Guanylate kinase PDZ PF00595.24 CDS28936.1 - 1.8e-08 34.6 0.5 3.2e-08 33.8 0.5 1.4 1 0 0 1 1 1 1 PDZ domain L27 PF02828.16 CDS28936.1 - 4.9e-05 23.0 0.0 0.4 10.5 0.0 2.9 2 0 0 2 2 2 2 L27 domain PDZ_6 PF17820.1 CDS28936.1 - 7e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CDS28936.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 CDS28936.1 - 0.00096 19.4 0.2 0.0021 18.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS28936.1 - 0.013 15.1 0.1 0.035 13.7 0.1 1.8 1 1 0 1 1 1 0 SH3 domain Ribosomal_S7 PF00177.21 CDS28937.1 - 6.8e-35 119.9 0.7 8.3e-35 119.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e LRR_8 PF13855.6 CDS28938.1 - 1.1e-10 41.1 15.7 7.7e-07 28.8 2.1 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDS28938.1 - 9.2e-10 38.6 5.7 3.8e-05 24.0 0.3 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS28938.1 - 0.00011 22.2 4.9 2.8 8.8 0.6 4.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_5 PF13306.6 CDS28938.1 - 0.0065 16.4 0.8 0.023 14.6 0.7 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CDS28938.1 - 0.064 13.3 7.8 9.3 6.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat HA2 PF04408.23 CDS28940.1 - 5.6e-15 55.6 0.0 1.8e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDS28940.1 - 2.8e-11 43.7 0.0 8.2e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS28940.1 - 1.1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CDS28940.1 - 7.6e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE PF00437.20 CDS28940.1 - 0.00087 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CDS28940.1 - 0.0018 18.5 0.1 0.0099 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDS28940.1 - 0.012 15.9 0.0 0.041 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CDS28940.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CDS28940.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDS28940.1 - 0.032 14.7 2.1 0.043 14.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 CDS28940.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC SCO1-SenC PF02630.14 CDS28941.1 - 3.4e-45 153.2 0.0 6.3e-45 152.4 0.0 1.4 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 CDS28941.1 - 1.4e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CDS28941.1 - 9.5e-06 25.9 0.0 9.9e-05 22.6 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CDS28941.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 CDS28941.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Redoxin F-box-like PF12937.7 CDS28942.2 - 2.6e-11 43.2 2.3 6e-11 42.1 2.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDS28942.2 - 8.9e-09 35.0 1.3 8.9e-09 35.0 1.3 3.0 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 CDS28942.2 - 0.018 15.5 0.6 0.018 15.5 0.6 6.0 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 CDS28942.2 - 0.07 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box RhoGAP PF00620.27 CDS28943.1 - 6.2e-37 126.8 0.0 2e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.28 CDS28943.1 - 2.8e-07 30.0 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS28943.1 - 4.9e-05 23.1 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RNA_pol_Rpb6 PF01192.22 CDS28944.1 - 2.4e-16 59.4 0.2 3.3e-16 58.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 QRPTase_C PF01729.19 CDS28945.1 - 4.5e-18 65.6 0.0 2.1e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CDS28945.1 - 7.2e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain ADK PF00406.22 CDS28946.1 - 1.3e-26 93.5 0.0 1.7e-22 80.1 0.0 2.5 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CDS28946.1 - 1e-12 48.7 0.0 9.7e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain F-box PF00646.33 CDS28946.1 - 2.3e-07 30.5 0.0 6.5e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDS28946.1 - 1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like AAA_18 PF13238.6 CDS28946.1 - 0.00031 21.3 0.0 0.00074 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain LRR_6 PF13516.6 CDS28946.1 - 0.0091 16.0 8.7 0.41 10.8 0.2 5.1 6 0 0 6 6 6 1 Leucine Rich repeat AAA_33 PF13671.6 CDS28946.1 - 0.036 14.2 0.0 0.095 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.7 CDS28946.1 - 0.19 12.2 12.0 24 5.5 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Thymidylate_kin PF02223.17 CDS28946.1 - 0.34 10.5 2.8 21 4.7 0.5 3.7 3 1 0 3 3 3 0 Thymidylate kinase RT_RNaseH PF17917.1 CDS28950.1 - 7.1e-15 55.2 0.1 1.3e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS28950.1 - 9.4e-11 41.6 0.3 2.1e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SH3_11 PF18103.1 CDS28950.1 - 0.028 14.6 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain TFIIB PF00382.19 CDS28951.1 - 1.8e-31 108.0 1.0 3.5e-16 59.0 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CDS28951.1 - 4.1e-18 65.6 7.3 1.3e-17 64.0 7.3 1.9 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CDS28951.1 - 1.5e-07 30.8 2.5 1.5e-07 30.8 2.5 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 CDS28951.1 - 0.0019 17.9 0.2 0.32 10.7 0.1 2.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS28951.1 - 0.0055 16.8 0.3 0.073 13.2 0.0 2.8 3 0 0 3 3 3 1 Cyclin, C-terminal domain YhfH PF14149.6 CDS28951.1 - 0.4 10.7 2.8 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 CDS28951.1 - 1.7 8.2 4.5 9.1 5.8 4.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain V_ATPase_I PF01496.19 CDS28952.1 - 0 1049.0 0.0 0 1048.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Kinesin PF00225.23 CDS28953.1 - 9e-08 31.4 1.0 1.7e-07 30.5 0.9 1.4 1 1 0 1 1 1 1 Kinesin motor domain BUD22 PF09073.10 CDS28953.1 - 0.03 13.7 1.0 0.034 13.5 1.0 1.1 1 0 0 1 1 1 0 BUD22 Myosin_tail_1 PF01576.19 CDS28954.1 - 5.4e-49 166.9 172.5 7.2e-49 166.5 172.5 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 CDS28954.1 - 0.00041 20.0 153.3 0.00095 18.8 44.0 6.0 1 1 3 4 4 4 3 Intermediate filament protein CENP-F_leu_zip PF10473.9 CDS28954.1 - 0.00099 19.1 9.4 0.00099 19.1 9.4 8.9 1 1 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.6 CDS28954.1 - 0.0074 15.8 10.8 0.0074 15.8 10.8 7.3 1 1 6 7 7 7 1 Leucine zipper TMF_TATA_bd PF12325.8 CDS28954.1 - 0.023 14.9 1.0 0.023 14.9 1.0 11.5 1 1 11 13 13 13 0 TATA element modulatory factor 1 TATA binding Sugarporin_N PF11471.8 CDS28954.1 - 0.04 13.9 0.2 0.04 13.9 0.2 9.4 7 2 2 9 9 9 0 Maltoporin periplasmic N-terminal extension Spc7 PF08317.11 CDS28954.1 - 1.7 7.4 169.8 0.056 12.3 16.3 8.0 1 1 7 8 8 8 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDS28954.1 - 1.8 8.6 93.2 0.17 11.9 4.2 10.3 2 2 9 13 13 13 0 Protein of unknown function (DUF1664) Cadherin PF00028.17 CDS28955.1 - 3.1e-08 33.9 0.0 9.1e-07 29.2 0.0 3.2 2 1 0 2 2 2 1 Cadherin domain RhoGEF PF00621.20 CDS28959.2 - 1.6e-22 80.6 0.5 2.4e-18 67.0 0.1 2.4 2 0 0 2 2 2 2 RhoGEF domain Fijivirus_P9-2 PF06837.11 CDS28959.2 - 0.093 12.2 0.3 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein Proteasom_PSMB PF10508.9 CDS28960.2 - 2.1e-38 132.1 0.1 2.5e-36 125.2 0.0 2.0 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 CDS28960.2 - 0.09 13.0 0.3 12 6.1 0.2 3.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 S4 PF01479.25 CDS28961.2 - 4.7e-12 45.4 0.0 1e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 S4 domain Tropomyosin PF00261.20 CDS28961.2 - 0.043 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin Ribosomal_S4 PF00163.19 CDS28961.2 - 0.043 14.7 0.2 0.085 13.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Y_phosphatase PF00102.27 CDS28962.2 - 5.4e-69 232.3 0.0 7.9e-50 169.6 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.20 CDS28962.2 - 6e-09 35.8 0.0 6.2e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain fn3 PF00041.21 CDS28962.2 - 8.4e-07 29.3 0.2 0.0095 16.3 0.0 3.5 4 0 0 4 4 4 2 Fibronectin type III domain GKAP PF03359.13 CDS28964.1 - 1.8e-14 54.1 0.3 1.8e-14 54.1 0.3 2.8 3 1 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein AT_hook PF02178.19 CDS28964.1 - 0.0023 17.6 82.8 0.46 10.5 0.2 11.8 10 0 0 10 10 10 8 AT hook motif DASH_Duo1 PF08651.10 CDS28964.1 - 0.068 13.0 0.3 0.2 11.4 0.3 1.8 1 0 0 1 1 1 0 DASH complex subunit Duo1 PLCC PF14466.6 CDS28965.1 - 0.029 14.5 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Spectrin PF00435.21 CDS28968.2 - 1.1e-252 819.8 153.3 2.3e-23 82.7 8.2 17.6 18 0 0 18 18 18 17 Spectrin repeat CH PF00307.31 CDS28968.2 - 1.2e-46 157.3 9.9 6.1e-25 87.5 0.1 4.5 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.6 CDS28968.2 - 3.9e-20 72.4 0.4 5.9e-19 68.6 0.0 3.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CDS28968.2 - 1.5e-13 51.2 0.0 8e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 PH domain CAMSAP_CH PF11971.8 CDS28968.2 - 1.3e-06 28.1 0.2 0.00033 20.4 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain FIVAR PF07554.13 CDS28968.2 - 8.5 7.2 10.4 14 6.6 0.3 4.5 4 0 0 4 4 4 0 FIVAR domain CTP_synth_N PF06418.14 CDS28970.1 - 7.6e-122 405.7 0.0 9.7e-122 405.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CDS28970.1 - 5.1e-45 153.6 0.0 1.4e-33 116.2 0.0 3.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDS28970.1 - 0.00053 19.8 0.5 0.015 15.0 0.1 2.4 2 0 0 2 2 2 1 Peptidase C26 gag-asp_proteas PF13975.6 CDS28971.1 - 0.015 15.9 0.0 0.044 14.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS28971.1 - 0.075 13.7 0.0 0.24 12.0 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 CDS28972.1 - 4.4e-17 61.9 1.7 7e-17 61.3 1.7 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS28972.1 - 4.6e-05 23.5 0.3 8.8e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Lig_chan PF00060.26 CDS28974.1 - 1.1e-18 67.5 0.1 5.4e-18 65.3 0.1 2.2 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDS28974.1 - 3.5e-11 43.0 0.0 7.3e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 CDS28974.1 - 0.011 15.9 0.0 0.074 13.3 0.0 2.2 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site MpPF26 PF07666.11 CDS28974.1 - 9.9 6.3 19.7 0.19 11.8 3.7 3.3 2 1 0 2 2 2 0 M penetrans paralogue family 26 zf-C2H2 PF00096.26 CDS28975.1 - 1.5e-08 34.6 8.0 0.11 12.9 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS28975.1 - 1.1e-07 32.1 7.3 0.21 12.5 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS28975.1 - 3.5e-05 24.0 6.1 0.0011 19.3 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS28975.1 - 0.0054 17.0 5.7 1.7 9.1 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS28975.1 - 0.052 13.8 6.2 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 CDS28975.1 - 0.068 13.2 5.3 4 7.5 0.1 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 CDS28975.1 - 0.076 13.4 7.5 0.43 10.9 0.2 3.1 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Disulph_isomer PF06491.11 CDS28975.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase CpXC PF14353.6 CDS28975.1 - 0.25 11.4 2.2 7.3 6.7 0.3 2.7 2 0 0 2 2 2 0 CpXC protein zf-C2H2_3rep PF18868.1 CDS28975.1 - 0.28 11.8 5.3 0.35 11.5 0.2 3.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 CDS28975.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.9 3 1 1 4 4 4 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 CDS28975.1 - 0.61 10.3 3.3 12 6.1 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 CDS28975.1 - 1.1 9.0 3.5 9.2 6.1 0.0 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 CDS28975.1 - 2.9 7.9 4.7 7.2 6.7 0.0 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_9 PF14369.6 CDS28975.1 - 8.7 6.7 6.8 1.7 9.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon Cystatin PF00031.21 CDS28976.1 - 0.00011 22.4 0.5 0.00029 21.0 0.1 1.9 2 0 0 2 2 2 1 Cystatin domain Fer4_22 PF17179.4 CDS28976.1 - 0.036 14.9 1.2 0.17 12.8 0.8 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Latexin PF06907.12 CDS28977.1 - 0.054 13.0 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Latexin RNA_pol_Rpb1_5 PF04998.17 CDS28979.1 - 8.3e-75 251.6 0.0 1.7e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDS28979.1 - 4.4e-60 202.7 0.0 1.1e-59 201.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDS28979.1 - 5.6e-33 114.1 0.0 1.3e-32 112.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDS28979.1 - 2.4e-21 76.4 0.0 1.7e-19 70.3 0.0 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CDS28979.1 - 5.2e-16 58.5 0.0 1.9e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 LSM PF01423.22 CDS28980.1 - 1.4e-18 66.4 0.4 1.5e-18 66.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDS28980.1 - 6.3e-05 23.0 0.0 7.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CDS28980.1 - 0.013 15.6 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Tetraspanin PF00335.20 CDS28981.1 - 8e-31 107.5 9.1 1.1e-30 107.0 9.1 1.2 1 0 0 1 1 1 1 Tetraspanin family SPACA7 PF15307.6 CDS28981.1 - 0.16 12.2 0.0 0.23 11.8 0.0 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 NAD_binding_6 PF08030.12 CDS28982.2 - 0.26 11.4 3.2 1.1 9.4 1.1 2.5 2 1 0 2 2 2 0 Ferric reductase NAD binding domain PRK PF00485.18 CDS28984.1 - 2e-19 70.1 0.2 2.5e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family F-box PF00646.33 CDS28985.2 - 8.1e-09 35.2 0.2 1.6e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDS28985.2 - 5.4e-06 26.2 1.2 1.2e-05 25.1 1.2 1.6 1 0 0 1 1 1 1 F-box-like DUF3990 PF13151.6 CDS28985.2 - 0.061 13.0 0.3 0.074 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) F-box_4 PF15966.5 CDS28985.2 - 0.19 11.6 0.2 0.19 11.6 0.2 2.3 1 1 1 2 2 2 0 F-box Ada3 PF10198.9 CDS28987.2 - 2.2e-09 37.6 3.6 5e-09 36.4 3.6 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 SRC-1 PF08832.10 CDS28987.2 - 0.76 10.9 0.1 0.76 10.9 0.1 3.5 2 1 1 3 3 3 0 Steroid receptor coactivator PRK PF00485.18 CDS28990.1 - 2.1e-41 141.9 0.1 2.4e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family F-box PF00646.33 CDS28991.2 - 3.3e-08 33.2 0.3 3.3e-08 33.2 0.3 1.8 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 CDS28991.2 - 2.3e-07 31.4 0.2 8.8e-07 29.5 0.2 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat F-box-like PF12937.7 CDS28991.2 - 8e-05 22.4 1.3 0.00026 20.8 1.3 1.9 1 0 0 1 1 1 1 F-box-like NUDIX PF00293.28 CDS28992.1 - 2.5e-09 37.2 0.1 6.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain NUDIX_2 PF13869.6 CDS28992.1 - 0.04 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Transposase_1 PF01359.18 CDS28993.1 - 5.9e-06 26.0 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Tetraspanin PF00335.20 CDS28994.1 - 3.8e-22 79.1 17.2 1.2e-17 64.5 2.7 2.0 1 1 1 2 2 2 2 Tetraspanin family F-box PF00646.33 CDS28996.2 - 4.8e-09 35.9 0.4 2.1e-08 33.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 CDS28996.2 - 6.7e-08 33.1 0.3 2.9e-05 24.7 0.3 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box-like PF12937.7 CDS28996.2 - 0.00038 20.3 1.3 0.00038 20.3 1.3 2.1 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 CDS28996.2 - 0.0063 16.8 0.2 8.6 6.7 0.0 4.1 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Tetraspanin PF00335.20 CDS28997.2 - 2.5e-37 128.8 13.4 2.8e-37 128.6 13.4 1.0 1 0 0 1 1 1 1 Tetraspanin family FAP206 PF12018.8 CDS28999.2 - 0.00058 19.4 1.2 0.00073 19.1 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF2680 PF10925.8 CDS28999.2 - 0.13 12.3 2.3 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Nup54_C PF18437.1 CDS28999.2 - 0.15 12.0 2.5 0.31 11.0 2.5 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Dynein_light PF01221.18 CDS29000.1 - 1.1e-40 137.9 0.5 1.2e-40 137.7 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 IBN_N PF03810.19 CDS29002.1 - 0.00062 19.6 0.7 0.0027 17.6 0.2 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain MAM33 PF02330.16 CDS29003.1 - 2.9e-11 43.7 0.5 2.2e-10 40.8 0.5 1.9 1 1 0 1 1 1 1 Mitochondrial glycoprotein P_proprotein PF01483.20 CDS29003.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Dynein_light PF01221.18 CDS29004.1 - 2.5e-33 114.2 0.0 2.9e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 CDS29004.1 - 0.049 13.6 0.0 0.052 13.5 0.0 1.0 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) KIP1 PF07765.12 CDS29004.1 - 0.11 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 KIP1-like protein Dynein_light PF01221.18 CDS29005.1 - 1.9e-29 101.8 3.1 2.2e-29 101.6 3.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 HTH_33 PF13592.6 CDS29005.1 - 0.0038 16.8 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix RP853 PF17542.2 CDS29005.1 - 0.037 13.2 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Dynein_light PF01221.18 CDS29006.1 - 3.5e-40 136.2 3.5 3.9e-40 136.1 3.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 YtxH PF12732.7 CDS29006.1 - 0.46 11.1 2.6 0.68 10.5 2.6 1.4 1 0 0 1 1 1 0 YtxH-like protein SpoIIIAH PF12685.7 CDS29006.1 - 0.54 10.1 4.2 0.64 9.8 4.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 CDS29007.1 - 1.3e-54 185.7 4.1 1.8e-54 185.2 4.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Dynein_light PF01221.18 CDS29007.1 - 1.9e-40 137.1 1.6 1.9e-40 137.1 1.6 1.8 2 0 0 2 2 2 1 Dynein light chain type 1 GTP_EFTU PF00009.27 CDS29008.1 - 1.7e-30 106.0 0.1 4.6e-30 104.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDS29008.1 - 4.1e-09 36.7 0.1 2.4e-08 34.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDS29008.1 - 8.3e-07 29.1 0.7 1.3e-06 28.4 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CDS29008.1 - 0.00018 21.2 0.8 0.0016 18.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CDS29008.1 - 0.0011 18.5 0.7 0.0032 16.9 0.7 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDS29008.1 - 0.002 17.5 0.1 0.0053 16.2 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDS29008.1 - 0.037 13.9 0.5 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CDS29008.1 - 0.11 12.2 0.5 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Calpain_inhib PF00748.19 CDS29008.1 - 0.16 12.4 0.2 0.37 11.3 0.2 1.5 1 0 0 1 1 1 0 Calpain inhibitor Septin PF00735.18 CDS29008.1 - 0.19 11.0 0.3 1.2 8.3 0.0 2.0 1 1 1 2 2 2 0 Septin ATP_bind_1 PF03029.17 CDS29008.1 - 0.26 11.1 1.2 28 4.4 0.1 2.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MscS_TM PF12794.7 CDS29009.1 - 0.056 12.3 6.6 1.5 7.6 0.7 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 F-box-like PF12937.7 CDS29009.1 - 0.064 13.2 0.3 0.44 10.5 0.1 2.4 2 0 0 2 2 2 0 F-box-like RPW8 PF05659.11 CDS29009.1 - 0.12 12.1 3.9 0.37 10.5 0.2 2.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMEM154 PF15102.6 CDS29009.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family Baculo_PEP_C PF04513.12 CDS29009.1 - 0.44 10.6 12.0 2.6 8.1 0.6 3.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3829 PF12889.7 CDS29009.1 - 0.73 9.3 10.1 0.028 13.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF948 PF06103.11 CDS29009.1 - 1.2 9.5 4.2 7.1 7.0 0.4 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PRANC PF09372.10 CDS29009.1 - 1.2 9.5 0.0 1.2 9.5 0.0 4.2 3 1 0 4 4 4 0 PRANC domain EphA2_TM PF14575.6 CDS29009.1 - 7.9 7.4 5.4 6.8 7.6 0.0 3.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Homeodomain PF00046.29 CDS29010.1 - 2.3e-24 85.0 2.3 4.7e-24 84.0 2.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS29010.1 - 0.039 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain TDP43_N PF18694.1 CDS29011.1 - 6.9e-28 96.3 0.0 1.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain RRM_1 PF00076.22 CDS29011.1 - 1.5e-25 88.8 0.0 7.3e-12 44.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS29011.1 - 1.1e-05 25.4 0.0 0.091 12.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS29011.1 - 3.8e-05 23.6 0.0 0.0005 20.0 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 CDS29011.1 - 0.0046 16.9 0.0 0.097 12.6 0.0 2.4 2 0 0 2 2 2 1 RL domain MBOAT PF03062.19 CDS29012.1 - 2.3e-14 53.5 11.1 4.6e-14 52.5 11.1 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-C2H2 PF00096.26 CDS29013.1 - 3.6e-25 87.0 27.9 1.5e-05 25.2 0.7 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29013.1 - 2.3e-18 65.3 34.2 0.00072 20.2 0.5 6.0 6 0 0 6 6 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS29013.1 - 1.2e-15 57.2 28.5 6.3e-05 23.2 1.4 5.9 6 0 0 6 6 5 5 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDS29013.1 - 3.6e-08 33.0 24.1 0.13 12.0 0.8 5.4 5 0 0 5 5 5 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CDS29013.1 - 9.2e-08 31.9 26.7 0.014 15.4 1.8 5.9 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS29013.1 - 2.9e-06 27.4 13.9 0.21 11.9 0.1 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDS29013.1 - 0.0021 18.1 28.0 0.29 11.2 0.4 6.0 2 1 4 6 6 6 2 BED zinc finger zf-met PF12874.7 CDS29013.1 - 0.0029 18.0 20.7 0.78 10.2 0.2 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CDS29013.1 - 0.0083 16.8 10.1 0.17 12.6 0.1 3.8 1 1 3 4 4 4 1 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 CDS29013.1 - 0.011 15.8 13.3 0.18 11.8 0.4 3.5 3 1 0 3 3 3 0 Double zinc ribbon Elf1 PF05129.13 CDS29013.1 - 0.015 15.4 10.9 0.77 9.8 0.3 3.4 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 CDS29013.1 - 0.015 16.0 13.6 0.42 11.4 0.3 3.0 2 1 0 2 2 2 0 zinc-ribbon family C1_4 PF07975.12 CDS29013.1 - 0.021 15.1 14.1 0.46 10.8 1.3 3.6 2 1 0 3 3 3 0 TFIIH C1-like domain DUF2256 PF10013.9 CDS29013.1 - 0.022 14.9 10.0 5.6 7.2 0.0 4.9 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 CDS29013.1 - 0.03 14.2 0.2 0.03 14.2 0.2 4.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-TRAF PF02176.18 CDS29013.1 - 0.049 14.3 2.3 0.049 14.3 2.3 2.7 1 1 2 3 3 3 0 TRAF-type zinc finger Rpr2 PF04032.16 CDS29013.1 - 0.091 13.1 15.4 2.2 8.6 9.2 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 CDS29013.1 - 0.093 12.9 15.2 1.4 9.1 2.9 3.9 1 1 2 4 4 4 0 Zinc ribbon domain HypA PF01155.19 CDS29013.1 - 0.15 12.1 11.1 3 7.9 1.9 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA XPA_N PF01286.18 CDS29013.1 - 0.24 11.5 10.3 18 5.5 0.0 4.9 5 0 0 5 5 5 0 XPA protein N-terminal zf-AN1 PF01428.16 CDS29013.1 - 0.24 11.6 14.8 23 5.3 0.2 5.2 5 0 0 5 5 5 0 AN1-like Zinc finger zf-C2HE PF16278.5 CDS29013.1 - 0.29 11.6 18.1 2.3 8.8 0.2 5.0 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger YhfH PF14149.6 CDS29013.1 - 0.34 10.9 9.7 12 5.9 0.3 4.4 4 0 0 4 4 4 0 YhfH-like protein zf-C2H2_2 PF12756.7 CDS29013.1 - 1 9.8 19.7 2.1 8.7 1.6 4.8 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 CDS29013.1 - 1.3 9.2 22.8 4.4 7.5 5.3 3.2 1 1 2 3 3 3 0 FYVE zinc finger zf_UBZ PF18439.1 CDS29013.1 - 1.4 8.5 14.1 2 8.1 0.1 5.5 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 CDS29013.1 - 3.5 7.8 7.7 62 3.8 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger domain Zn_ribbon_recom PF13408.6 CDS29013.1 - 8.9 6.9 17.5 8.2 7.0 1.9 3.5 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain WD40 PF00400.32 CDS29015.1 - 9.4e-47 156.0 9.0 7.5e-08 32.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS29015.1 - 2.6e-12 46.9 0.4 0.21 11.9 0.1 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDS29015.1 - 5.7e-06 26.4 0.1 0.0099 15.8 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDS29015.1 - 0.00022 20.3 0.0 0.56 9.1 0.0 3.4 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDS29015.1 - 0.00065 18.3 0.3 0.43 9.1 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 CDS29015.1 - 0.0052 15.5 2.0 0.77 8.3 0.1 3.2 2 2 1 3 3 3 1 Nucleoporin Nup120/160 M64_N PF16217.5 CDS29015.1 - 0.022 14.3 0.1 67 3.1 0.0 3.8 4 0 0 4 4 4 0 Peptidase M64 N-terminus Nbas_N PF15492.6 CDS29015.1 - 0.039 13.3 0.0 1.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 CDS29015.1 - 0.079 13.5 0.6 27 5.4 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain TTL PF03133.15 CDS29016.1 - 7.3e-54 182.9 0.2 1.1e-53 182.4 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDS29016.1 - 3.1e-11 43.0 0.0 4e-06 26.3 0.0 2.9 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDS29016.1 - 0.0004 19.7 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CDS29016.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GSH-S_ATP PF02955.16 CDS29016.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 CDS29016.1 - 0.013 15.1 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Sec1 PF00995.23 CDS29017.1 - 5.7e-48 164.5 0.0 1e-47 163.7 0.0 1.4 1 1 0 1 1 1 1 Sec1 family RT_RNaseH_2 PF17919.1 CDS29020.2 - 1e-13 51.2 0.1 2.4e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS29020.2 - 2.5e-07 30.4 0.0 5.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDS29020.2 - 1.2e-06 28.7 0.6 4.6e-06 26.9 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase FAD_SOX PF18371.1 CDS29020.2 - 0.056 13.8 0.2 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Pkinase PF00069.25 CDS29021.1 - 9e-70 235.0 0.1 1.2e-69 234.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29021.1 - 5e-40 137.4 0.0 6.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CDS29021.1 - 5.4e-38 129.0 1.4 4.7e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CDS29021.1 - 6.5e-10 38.8 0.2 6.9e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CDS29021.1 - 3.3e-05 22.8 0.1 5.1e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase AAA PF00004.29 CDS29022.1 - 8.2e-97 320.7 0.0 4e-47 159.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS29022.1 - 9.4e-23 79.8 7.8 4.8e-12 45.5 1.2 3.4 2 2 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CDS29022.1 - 3.6e-16 59.1 0.6 1.8e-15 56.8 0.6 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDS29022.1 - 4.4e-14 52.5 0.0 1.8e-05 24.6 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS29022.1 - 4.7e-14 53.1 0.3 9.8e-05 22.8 0.1 4.6 3 2 0 3 3 2 2 AAA ATPase domain CDC48_2 PF02933.17 CDS29022.1 - 5.9e-12 45.2 0.0 1.9e-11 43.6 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 CDS29022.1 - 3.3e-11 43.5 0.0 2.7e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CDS29022.1 - 5.7e-11 42.8 0.0 4.4e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDS29022.1 - 4.2e-10 39.8 0.2 0.00014 21.9 0.0 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS29022.1 - 1.2e-09 38.6 0.2 0.017 15.4 0.1 4.2 2 2 1 3 3 3 2 AAA domain Vps4_C PF09336.10 CDS29022.1 - 3.5e-09 36.5 0.3 1.8e-05 24.6 0.1 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CDS29022.1 - 2.5e-08 33.5 0.0 0.0024 17.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CDS29022.1 - 5.6e-08 33.4 0.0 0.026 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CDS29022.1 - 2.8e-07 30.9 0.0 0.0053 17.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CDS29022.1 - 4.9e-07 29.3 0.3 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDS29022.1 - 5.5e-07 29.7 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDS29022.1 - 7.3e-07 29.1 0.0 0.054 13.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 CDS29022.1 - 2.2e-06 27.0 0.0 0.036 13.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 CDS29022.1 - 2.8e-06 27.0 0.0 0.056 13.0 0.0 3.4 3 1 0 3 3 3 2 P-loop containing dynein motor region ATPase_2 PF01637.18 CDS29022.1 - 4e-06 26.9 0.1 0.25 11.2 0.0 3.8 2 2 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CDS29022.1 - 6.1e-06 26.6 0.1 0.15 12.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 CDS29022.1 - 1.6e-05 25.5 0.0 0.014 15.9 0.0 3.2 2 1 0 2 2 2 1 ABC transporter ATPase PF06745.13 CDS29022.1 - 2e-05 24.1 0.0 1.4 8.2 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 CDS29022.1 - 4.4e-05 23.2 2.4 3.4 7.2 0.0 3.8 2 2 1 4 4 4 0 AAA domain Bac_DnaA PF00308.18 CDS29022.1 - 4.6e-05 23.4 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 CDS29022.1 - 4.7e-05 23.2 0.0 0.11 12.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CDS29022.1 - 6.3e-05 22.7 0.0 0.26 11.0 0.0 2.9 2 2 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 CDS29022.1 - 8e-05 22.6 0.0 0.34 10.9 0.0 2.7 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CDS29022.1 - 8.1e-05 22.5 0.0 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CDS29022.1 - 0.00013 22.4 0.0 0.91 9.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 CDS29022.1 - 0.00016 21.7 0.1 0.34 10.8 0.0 3.5 3 1 0 4 4 4 1 NACHT domain DUF815 PF05673.13 CDS29022.1 - 0.0003 20.0 0.0 0.21 10.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CDS29022.1 - 0.00033 19.9 0.0 0.28 10.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 CDS29022.1 - 0.00041 20.5 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain UFD1 PF03152.14 CDS29022.1 - 0.00045 19.7 0.0 0.00095 18.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 CDS29022.1 - 0.0006 19.1 0.0 0.53 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.9 CDS29022.1 - 0.00083 18.7 0.0 0.34 10.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CDS29022.1 - 0.00084 19.4 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CDS29022.1 - 0.0012 18.4 0.2 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 CDS29022.1 - 0.0018 18.2 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CDS29022.1 - 0.0021 17.9 0.2 2.2 8.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CDS29022.1 - 0.0042 17.4 0.4 3.2 8.1 0.1 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 CDS29022.1 - 0.0077 16.2 0.0 1.1 9.1 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain Molydop_binding PF01568.21 CDS29022.1 - 0.012 15.7 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_30 PF13604.6 CDS29022.1 - 0.017 14.8 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDS29022.1 - 0.032 14.1 0.1 5.4 6.9 0.0 3.1 3 0 0 3 3 3 0 NTPase KAP_NTPase PF07693.14 CDS29022.1 - 0.053 12.8 0.1 1.7 7.8 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain SKI PF01202.22 CDS29022.1 - 0.075 13.1 0.2 7.7 6.6 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CDS29022.1 - 0.11 12.3 0.0 23 4.7 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 CDS29022.1 - 0.14 11.9 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zot PF05707.12 CDS29022.1 - 0.14 11.8 0.0 2.1 8.0 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_23 PF13476.6 CDS29022.1 - 0.15 12.5 0.2 15 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Hydin_ADK PF17213.3 CDS29022.1 - 0.88 9.8 3.6 39 4.4 0.2 3.5 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain Kelch_1 PF01344.25 CDS29023.1 - 8.4e-21 73.3 0.1 6.2e-08 32.1 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDS29023.1 - 3.3e-14 52.6 0.0 2.1e-05 24.6 0.0 3.8 3 1 1 4 4 4 2 Kelch motif BACK PF07707.15 CDS29023.1 - 5.3e-09 36.1 0.1 4.7e-07 29.9 0.1 2.3 1 1 1 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.6 CDS29023.1 - 7.7e-07 29.3 0.9 0.02 15.2 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS29023.1 - 8.5e-07 28.8 0.2 0.0056 16.6 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDS29023.1 - 1.4e-06 28.2 0.2 0.0059 16.6 0.0 3.8 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS29023.1 - 0.0022 17.9 0.4 0.37 10.9 0.0 3.9 5 0 0 5 5 5 1 Kelch motif BTB PF00651.31 CDS29023.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain HTH_46 PF15977.5 CDS29023.1 - 0.059 13.4 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding DSPc PF00782.20 CDS29023.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS29024.1 - 1.1e-63 215.0 3.2 4.5e-31 108.2 0.3 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.20 CDS29024.1 - 0.00054 19.8 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS29024.1 - 0.0094 15.9 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Bcl-2 PF00452.19 CDS29025.1 - 1.2e-14 54.8 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family EST1_DNA_bind PF10373.9 CDS29027.1 - 1.1e-30 107.2 0.1 8.4e-30 104.2 0.0 2.3 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 CDS29027.1 - 3.6e-15 56.4 2.0 6.6e-15 55.6 0.0 2.5 2 0 0 2 2 2 1 PIN domain EST1 PF10374.9 CDS29027.1 - 2.2e-08 34.8 0.0 1.9e-07 31.8 0.0 2.7 2 0 0 2 2 2 1 Telomerase activating protein Est1 PIN_9 PF18477.1 CDS29027.1 - 0.023 15.0 0.2 16 5.8 0.0 3.6 3 0 0 3 3 3 0 PIN like domain TPR_17 PF13431.6 CDS29027.1 - 0.027 14.8 0.0 0.14 12.6 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3987 PF13148.6 CDS29027.1 - 0.04 12.9 2.8 0.48 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) JAB PF01398.21 CDS29028.1 - 8.1e-32 109.7 0.6 1.4e-31 108.9 0.6 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDS29028.1 - 1.6e-08 34.4 0.1 2.6e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDS29028.1 - 3.8e-07 30.3 0.7 9.5e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) CSN5_C PF18323.1 CDS29028.1 - 4.8e-06 27.4 0.8 2.6e-05 25.1 0.8 2.2 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain DUF4807 PF16065.5 CDS29028.1 - 0.016 14.9 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Hist_deacetyl PF00850.19 CDS29029.1 - 7.8e-76 255.5 0.0 3e-75 253.5 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain Aminotran_5 PF00266.19 CDS29030.1 - 5.4e-29 101.3 0.0 1.9e-28 99.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 CDS29030.1 - 8.8e-12 45.1 0.0 2.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 PP-loop family PPDK_N PF01326.19 CDS29030.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF5423 PF17461.2 CDS29030.1 - 4.3 6.1 5.4 7.8 5.3 5.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) TPK_catalytic PF04263.16 CDS29031.1 - 8.1e-31 106.6 0.0 1.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDS29031.1 - 7.2e-14 51.3 0.0 1.6e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TetR_C_37 PF18665.1 CDS29031.1 - 0.092 13.4 0.3 0.14 12.8 0.3 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_6 PF12774.7 CDS29032.1 - 1.4e-127 425.2 1.5 3.3e-125 417.4 0.0 4.5 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CDS29032.1 - 1.5e-123 413.4 6.8 1.5e-123 413.4 6.8 4.6 4 1 0 4 4 2 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDS29032.1 - 1.4e-114 383.3 12.5 1.4e-114 383.3 12.5 6.0 6 1 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CDS29032.1 - 7.4e-73 244.3 0.1 7.4e-73 244.3 0.1 4.7 4 1 1 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDS29032.1 - 8.5e-67 225.2 0.2 7e-66 222.2 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDS29032.1 - 3.5e-47 161.1 0.0 3.5e-47 161.1 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDS29032.1 - 1.9e-45 154.6 0.1 7.4e-39 133.1 0.0 5.1 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS29032.1 - 2.9e-39 134.5 0.0 6.4e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS29032.1 - 5.2e-37 127.7 14.0 9.3e-37 126.8 14.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS29032.1 - 5.5e-33 113.6 0.0 2.9e-32 111.3 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDS29032.1 - 5.2e-30 104.3 0.0 2.3e-12 47.1 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDS29032.1 - 1.3e-18 67.3 0.0 2.4e-17 63.2 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CDS29032.1 - 9.1e-17 61.6 4.8 0.018 15.4 0.0 7.1 7 0 0 7 7 5 4 AAA domain AAA PF00004.29 CDS29032.1 - 1e-14 55.1 0.0 0.0038 17.7 0.0 5.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CDS29032.1 - 8.8e-11 42.2 0.3 0.015 15.4 0.0 6.2 6 0 0 6 6 6 3 AAA domain AAA_16 PF13191.6 CDS29032.1 - 1.1e-10 42.1 0.1 2.9 8.3 0.0 7.6 7 0 0 7 7 6 2 AAA ATPase domain AAA_18 PF13238.6 CDS29032.1 - 3.1e-10 40.7 0.1 0.089 13.3 0.0 6.0 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.21 CDS29032.1 - 1.7e-07 30.8 0.2 0.069 12.5 0.0 4.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CDS29032.1 - 9.9e-05 21.5 0.0 0.11 11.5 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 CDS29032.1 - 0.00043 20.0 0.0 4 7.2 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CDS29032.1 - 0.00079 19.9 2.9 5.5 7.5 0.0 4.8 4 0 0 4 4 3 1 ABC transporter RNA_helicase PF00910.22 CDS29032.1 - 0.00087 19.6 0.0 2.4 8.6 0.0 5.0 5 0 0 5 5 4 1 RNA helicase AAA_24 PF13479.6 CDS29032.1 - 0.00096 18.9 0.0 26 4.5 0.0 4.8 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 CDS29032.1 - 0.0011 18.7 0.5 1.1 9.0 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 CDS29032.1 - 0.0037 16.9 1.8 0.72 9.4 0.0 4.3 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 CDS29032.1 - 0.0042 16.5 0.0 8 5.7 0.0 4.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 CDS29032.1 - 0.0051 17.0 0.0 0.028 14.6 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_30 PF13604.6 CDS29032.1 - 0.0051 16.5 7.0 9 6.0 0.0 4.9 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 CDS29032.1 - 0.038 14.3 7.1 0.17 12.2 0.0 5.1 5 0 0 5 5 5 0 AAA domain TsaE PF02367.17 CDS29032.1 - 0.2 11.6 0.5 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDS29032.1 - 0.22 11.4 2.8 45 3.9 0.0 4.6 5 0 0 5 5 4 0 NACHT domain Taxilin PF09728.9 CDS29032.1 - 0.8 8.8 30.7 0.2 10.8 25.0 3.1 2 1 0 2 2 2 0 Myosin-like coiled-coil protein RT_RNaseH_2 PF17919.1 CDS29034.1 - 8.3e-30 102.8 0.2 9.4e-30 102.6 0.2 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS29034.1 - 1.9e-23 82.7 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CDS29034.1 - 0.0026 17.8 0.1 0.0033 17.4 0.1 1.1 1 0 0 1 1 1 1 Pao retrotransposon peptidase Mgr1 PF08602.10 CDS29034.1 - 0.011 14.5 0.1 0.013 14.4 0.1 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit NOG1_N PF17835.1 CDS29038.1 - 0.0051 16.8 0.4 0.0089 16.0 0.4 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain PPR_long PF17177.4 CDS29038.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP DUF327 PF03885.13 CDS29038.1 - 0.06 13.3 0.2 0.13 12.2 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF327) BAP PF06639.11 CDS29038.1 - 0.083 13.2 0.3 0.18 12.1 0.3 1.5 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) SSP160 PF06933.11 CDS29038.1 - 1.5 6.9 5.2 1.8 6.7 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FerA PF08165.11 CDS29039.1 - 0.078 12.9 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain CK2S PF15011.6 CDS29039.1 - 0.19 11.6 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Vac14_Fig4_bd PF11916.8 CDS29040.1 - 1.3e-59 200.9 9.9 3.8e-59 199.3 9.9 1.9 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CDS29040.1 - 2.7e-33 114.5 3.0 9.5e-30 103.1 0.1 4.7 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDS29040.1 - 3.3e-13 48.7 3.2 0.002 18.2 0.1 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CDS29040.1 - 3.7e-12 46.5 2.7 0.0001 22.7 0.0 4.7 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 CDS29040.1 - 1.4e-06 28.6 0.1 0.12 12.7 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CDS29040.1 - 7e-06 26.2 11.0 0.0051 16.9 0.1 4.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 CDS29040.1 - 0.0017 17.0 0.1 0.0045 15.6 0.1 1.7 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 CDS29040.1 - 0.01 16.0 0.4 6.6 7.0 0.0 3.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 CDS29040.1 - 0.042 13.4 7.0 2 7.9 0.2 4.3 3 1 2 5 5 5 0 Tti2 family DUF3385 PF11865.8 CDS29040.1 - 0.052 13.5 0.1 4 7.3 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) adh_short PF00106.25 CDS29041.2 - 2e-05 24.2 0.0 5.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase PhnH PF05845.12 CDS29041.2 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Axin_b-cat_bind PF08833.10 CDS29042.1 - 0.019 15.0 5.0 0.071 13.2 5.0 2.0 1 0 0 1 1 1 0 Axin beta-catenin binding domain Nipped-B_C PF12830.7 CDS29043.1 - 6.3e-62 208.9 0.7 6.3e-62 208.9 0.7 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cnd1 PF12717.7 CDS29043.1 - 1.6e-06 28.3 2.8 0.0038 17.3 0.0 3.3 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 CDS29043.1 - 2.4e-06 27.7 3.1 3.4e-06 27.2 0.2 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CDS29043.1 - 0.029 14.6 10.8 3.6 8.1 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat ENTH PF01417.20 CDS29044.1 - 6.1e-45 152.3 0.2 1.1e-44 151.5 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDS29044.1 - 0.00071 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 ANTH domain DGF-1_C PF11040.8 CDS29044.1 - 0.0044 17.0 0.3 0.0044 17.0 0.3 3.4 4 2 0 4 4 4 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus UIM PF02809.20 CDS29044.1 - 2.5 8.2 8.6 0.67 10.0 3.3 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif PAE PF03283.13 CDS29045.1 - 3.8e-60 203.9 0.0 8.1e-60 202.8 0.0 1.4 1 1 0 1 1 1 1 Pectinacetylesterase DUF2321 PF10083.9 CDS29046.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) SSXT PF05030.12 CDS29047.1 - 8.5e-22 76.6 8.7 1.5e-21 75.8 8.7 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Elf4 PF07011.11 CDS29047.1 - 0.12 12.3 4.0 0.21 11.5 4.0 1.3 1 0 0 1 1 1 0 Early Flowering 4 domain Branch PF02485.21 CDS29048.1 - 4.9e-27 95.0 0.0 7.2e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme adh_short PF00106.25 CDS29049.1 - 1.1e-35 122.9 0.0 8e-35 120.1 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase JHD PF17811.1 CDS29049.1 - 9.6e-17 61.4 0.1 2.3e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain adh_short_C2 PF13561.6 CDS29049.1 - 2.2e-14 53.6 0.0 7e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase JmjC PF02373.22 CDS29049.1 - 1.7e-10 41.4 0.1 1e-09 38.8 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase KR PF08659.10 CDS29049.1 - 1e-07 32.1 0.2 2.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 KR domain Cupin_8 PF13621.6 CDS29049.1 - 9.7e-05 22.2 0.0 0.00029 20.6 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Epimerase PF01370.21 CDS29049.1 - 0.004 16.7 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDS29049.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cupin_4 PF08007.12 CDS29049.1 - 0.091 12.2 0.1 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein SPRY PF00622.28 CDS29051.2 - 6.5e-11 42.4 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.24 CDS29051.2 - 1.6e-07 31.4 32.3 1.5e-05 25.0 6.5 5.0 5 0 0 5 5 4 2 B-box zinc finger zf-C3HC4_4 PF15227.6 CDS29051.2 - 2e-06 27.9 3.7 2e-06 27.9 3.7 3.8 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CDS29051.2 - 3.3e-05 23.7 1.0 3.3e-05 23.7 1.0 3.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS29051.2 - 3.9e-05 23.6 2.0 3.9e-05 23.6 2.0 3.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDS29051.2 - 0.00028 20.7 1.0 0.00028 20.7 1.0 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS29051.2 - 0.0005 20.0 0.9 0.0005 20.0 0.9 4.2 3 1 1 4 4 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDS29051.2 - 0.0011 18.7 0.9 0.0011 18.7 0.9 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.21 CDS29051.2 - 0.0013 19.0 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF1041 PF06292.17 CDS29051.2 - 0.072 13.5 0.8 0.21 12.0 0.8 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) FAM184 PF15665.5 CDS29051.2 - 0.091 12.5 7.0 0.17 11.6 7.0 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Eapp_C PF10238.9 CDS29051.2 - 0.48 10.5 12.0 0.83 9.7 0.1 3.5 3 1 0 3 3 3 0 E2F-associated phosphoprotein Phasin PF05597.11 CDS29051.2 - 0.59 10.1 2.9 1.2 9.1 2.9 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Baculo_PEP_C PF04513.12 CDS29051.2 - 0.63 10.1 2.8 1.2 9.2 2.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 CDS29051.2 - 4.9 7.6 11.5 4.7 7.6 8.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Pkinase PF00069.25 CDS29052.2 - 4.8e-23 81.9 0.1 9.2e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain HR1 PF02185.16 CDS29052.2 - 1.9e-12 47.1 12.0 1.1e-10 41.4 0.1 4.3 4 0 0 4 4 4 2 Hr1 repeat Pkinase_Tyr PF07714.17 CDS29052.2 - 1.3e-11 44.3 0.1 2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Laminin_I PF06008.14 CDS29052.2 - 0.031 14.0 3.3 0.079 12.6 3.3 1.6 1 0 0 1 1 1 0 Laminin Domain I Syntaxin-6_N PF09177.11 CDS29052.2 - 0.26 11.9 1.8 0.84 10.2 1.8 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TSC22 PF01166.18 CDS29052.2 - 0.51 10.7 1.7 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family FapA PF03961.13 CDS29052.2 - 0.55 8.8 4.7 1.2 7.7 4.7 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 CDS29052.2 - 0.7 10.1 9.5 0.073 13.3 3.7 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 CDS29052.2 - 1.9 8.9 4.7 6.3 7.2 1.7 2.9 2 0 0 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 CDS29052.2 - 3.9 6.5 9.7 3.1 6.8 5.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CDS29052.2 - 4.2 6.5 7.7 1.2 8.3 3.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein ATP-synt_G PF04718.15 CDS29053.1 - 2.8e-18 66.6 0.0 3.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Mon1 PF03164.14 CDS29054.1 - 1.4e-105 353.7 0.9 1.7e-105 353.5 0.9 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 PfkB PF00294.24 CDS29055.1 - 4.1e-48 164.2 0.0 5.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CDS29055.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MIP PF00230.20 CDS29056.1 - 4.7e-27 95.2 5.6 5.7e-27 94.9 5.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF777 PF05606.11 CDS29056.1 - 0.042 13.6 0.5 0.073 12.8 0.5 1.5 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) ECF_trnsprt PF12822.7 CDS29056.1 - 1.3 9.1 9.9 2.5 8.2 9.9 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component MIP PF00230.20 CDS29057.1 - 8.7e-28 97.6 10.3 2.4e-27 96.1 10.3 1.6 1 1 0 1 1 1 1 Major intrinsic protein Phage_holin_1 PF04531.13 CDS29057.1 - 0.057 14.0 0.1 0.21 12.2 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage holin CrgA PF06781.12 CDS29057.1 - 2.8 8.0 9.1 14 5.8 4.5 2.9 2 1 0 2 2 2 0 Cell division protein CrgA AMP-binding PF00501.28 CDS29059.2 - 7.9e-61 205.9 0.0 9.7e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDS29059.2 - 8.6e-05 23.4 0.5 0.0002 22.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AA_permease PF00324.21 CDS29060.2 - 2.2e-57 194.7 32.9 6.3e-42 143.8 9.3 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CDS29060.2 - 9.1e-33 113.9 12.3 9.5e-12 44.7 0.0 3.9 1 1 1 4 4 4 3 Solute carrier family 12 Wzy_C PF04932.15 CDS29060.2 - 4.3 7.0 10.7 3.9 7.1 0.8 2.9 3 0 0 3 3 3 0 O-Antigen ligase RRM_1 PF00076.22 CDS29061.1 - 8.3e-18 64.0 0.1 8.6e-07 28.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2 PF09337.10 CDS29062.1 - 0.012 15.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Ras PF00071.22 CDS29063.1 - 1.2e-45 155.0 0.0 1.9e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS29063.1 - 1.8e-15 57.2 0.0 5.8e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDS29063.1 - 5.3e-06 26.4 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 CDS29063.1 - 0.0001 21.8 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS29063.1 - 0.00048 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase CPT PF07931.12 CDS29063.1 - 0.0048 16.8 0.0 0.0063 16.4 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 CDS29063.1 - 0.022 15.2 0.1 0.027 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CDS29063.1 - 0.024 14.4 0.0 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CDS29063.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CDS29063.1 - 0.029 14.7 0.1 0.11 12.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 CDS29063.1 - 0.032 13.7 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 CDS29063.1 - 0.075 12.8 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 CDS29063.1 - 0.081 13.0 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 CDS29063.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 CDS29063.1 - 0.2 12.1 0.6 0.39 11.2 0.6 1.9 1 1 0 1 1 1 0 ABC transporter DUF2627 PF11118.8 CDS29064.1 - 0.06 13.9 0.3 0.11 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Glyco_hydro_20 PF00728.22 CDS29065.1 - 1.1e-77 261.8 0.0 1.9e-77 261.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CDS29065.1 - 0.00015 22.4 0.0 0.0003 21.5 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CDS29065.1 - 0.0045 17.8 0.0 0.007 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Usp PF00582.26 CDS29066.1 - 1.5e-29 103.3 0.0 2.6e-29 102.5 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family DUF4147 PF13660.6 CDS29067.1 - 2.7e-60 203.8 0.0 3.8e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 CDS29067.1 - 4.1e-21 75.2 0.0 7.1e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 MOFRL family tRNA-synt_1b PF00579.25 CDS29068.1 - 3.1e-57 194.1 0.0 3.8e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RRM_1 PF00076.22 CDS29069.1 - 1.1e-11 44.4 0.0 0.0054 16.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 CDS29070.1 - 1.1e-84 284.4 40.2 6.1e-46 157.3 15.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDS29070.1 - 2e-66 222.7 0.2 5.9e-34 117.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDS29070.1 - 9.1e-15 54.7 0.0 8.3e-07 28.7 0.1 3.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CDS29070.1 - 9.2e-09 34.6 0.6 0.00098 18.0 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CDS29070.1 - 2.4e-07 31.3 1.1 0.0013 19.1 0.0 3.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 CDS29070.1 - 4.5e-07 29.8 0.4 0.045 13.5 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CDS29070.1 - 4.1e-06 26.7 0.0 0.012 15.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDS29070.1 - 4.2e-06 27.1 1.2 0.039 14.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDS29070.1 - 6.2e-06 25.9 0.9 0.071 12.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain G-alpha PF00503.20 CDS29070.1 - 7.1e-06 25.4 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 CDS29070.1 - 8e-06 25.9 0.2 0.086 12.6 0.0 4.1 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDS29070.1 - 2.2e-05 24.4 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 CDS29070.1 - 5.5e-05 23.3 4.0 0.52 10.6 0.9 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 CDS29070.1 - 6.6e-05 23.3 0.3 1.8 9.0 0.3 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CDS29070.1 - 0.00023 20.5 0.0 0.14 11.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CDS29070.1 - 0.00071 19.1 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CDS29070.1 - 0.0022 17.9 0.6 2.2 8.2 0.0 3.5 3 0 0 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 CDS29070.1 - 0.0038 17.3 0.4 6.7 6.8 0.0 3.4 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CDS29070.1 - 0.0063 17.1 0.0 5.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CDS29070.1 - 0.009 16.5 0.0 0.87 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDS29070.1 - 0.017 14.7 0.1 3.5 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 CDS29070.1 - 0.021 14.8 0.0 0.77 9.8 0.0 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CDS29070.1 - 0.027 13.7 0.1 0.89 8.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 CDS29070.1 - 0.028 14.8 0.9 7.5 7.0 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 CDS29070.1 - 0.037 14.2 0.1 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CDS29070.1 - 0.039 13.7 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 CDS29070.1 - 0.052 14.0 0.1 25 5.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF2969 PF11184.8 CDS29070.1 - 0.065 13.7 0.1 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) ECH_2 PF16113.5 CDS29070.1 - 0.07 12.6 0.2 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase APS_kinase PF01583.20 CDS29070.1 - 0.08 12.8 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 CDS29070.1 - 0.16 11.7 0.1 8.5 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CDS29070.1 - 0.16 11.6 0.6 6.3 6.4 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MoaE PF02391.17 CDS29070.1 - 0.18 12.1 0.6 0.91 9.8 0.2 2.3 2 0 0 2 2 2 0 MoaE protein ABC_membrane PF00664.23 CDS29071.2 - 9.9e-84 281.2 24.1 4.7e-45 154.4 11.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDS29071.2 - 5.5e-38 130.6 0.0 3.4e-37 128.0 0.1 2.2 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDS29071.2 - 9.9e-08 31.7 0.2 0.00023 20.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDS29071.2 - 4e-05 24.1 0.6 0.00052 20.4 0.2 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CDS29071.2 - 0.00048 20.7 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS29071.2 - 0.00056 20.2 0.1 0.0032 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CDS29071.2 - 0.00066 19.6 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDS29071.2 - 0.00089 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CDS29071.2 - 0.0026 17.5 0.5 0.01 15.6 0.5 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDS29071.2 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 CDS29071.2 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 CDS29071.2 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase Zeta_toxin PF06414.12 CDS29071.2 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CDS29071.2 - 0.029 14.4 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDS29071.2 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 CDS29071.2 - 0.053 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 CDS29071.2 - 0.054 13.7 0.5 0.62 10.3 0.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 CDS29071.2 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain PRK PF00485.18 CDS29071.2 - 0.059 13.1 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 CDS29071.2 - 0.073 13.6 0.2 0.23 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF3987 PF13148.6 CDS29071.2 - 0.1 11.6 0.3 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 CDS29071.2 - 0.14 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain LapA_dom PF06305.11 CDS29071.2 - 5.1 7.0 7.4 1.5 8.7 1.2 3.3 4 0 0 4 4 3 0 Lipopolysaccharide assembly protein A domain ABC_membrane PF00664.23 CDS29073.1 - 1.4e-97 326.6 39.9 7.6e-51 173.4 17.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDS29073.1 - 1.1e-69 233.3 0.4 8.7e-37 126.7 0.1 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CDS29073.1 - 1.7e-13 50.5 3.2 0.00071 19.1 0.2 4.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDS29073.1 - 3.7e-09 37.0 0.6 0.0015 18.8 0.0 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 CDS29073.1 - 1.4e-08 34.0 2.8 0.002 17.0 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDS29073.1 - 2.6e-08 33.5 0.5 0.0031 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CDS29073.1 - 7.1e-08 33.0 2.7 0.0036 17.7 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CDS29073.1 - 8.4e-08 32.4 0.2 0.06 13.1 0.1 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDS29073.1 - 2.1e-07 31.0 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CDS29073.1 - 6.3e-06 26.1 0.5 0.032 14.0 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain G-alpha PF00503.20 CDS29073.1 - 4.6e-05 22.7 0.0 0.14 11.2 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 CDS29073.1 - 4.7e-05 23.2 5.7 0.087 12.5 0.7 3.9 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDS29073.1 - 5.2e-05 22.8 0.1 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 CDS29073.1 - 5.5e-05 23.6 1.3 1.5 9.3 0.2 4.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CDS29073.1 - 7.8e-05 23.3 0.1 0.086 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDS29073.1 - 9.2e-05 22.4 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 CDS29073.1 - 0.00011 21.5 0.0 0.1 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 CDS29073.1 - 0.00024 21.3 7.2 0.41 10.9 0.7 4.5 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CDS29073.1 - 0.00054 20.5 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDS29073.1 - 0.00059 19.8 0.1 2 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CDS29073.1 - 0.00069 19.7 0.1 1.3 9.2 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 CDS29073.1 - 0.0012 18.8 0.0 0.99 9.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 CDS29073.1 - 0.0031 17.1 0.9 0.68 9.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CDS29073.1 - 0.0043 17.1 0.0 7.7 6.6 0.0 3.5 3 1 1 4 4 4 0 AAA domain NB-ARC PF00931.22 CDS29073.1 - 0.0053 16.0 1.2 1.3 8.1 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_24 PF13479.6 CDS29073.1 - 0.0061 16.3 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDS29073.1 - 0.0079 16.6 0.0 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CDS29073.1 - 0.0093 16.1 0.0 4.4 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CDS29073.1 - 0.0099 16.0 0.2 0.54 10.3 0.0 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_17 PF13207.6 CDS29073.1 - 0.012 16.0 0.1 15 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 CDS29073.1 - 0.019 13.9 0.1 2.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain PRK PF00485.18 CDS29073.1 - 0.025 14.3 0.1 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CDS29073.1 - 0.04 14.2 0.1 6.8 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 CDS29073.1 - 0.042 11.8 0.0 0.083 10.8 0.0 1.4 1 0 0 1 1 1 0 Helicase ATP_bind_1 PF03029.17 CDS29073.1 - 0.071 12.9 0.3 4.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF2852 PF11014.8 CDS29073.1 - 0.15 12.2 1.1 0.55 10.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) MINDY_DUB PF04424.13 CDS29074.1 - 2.5e-33 114.6 0.3 5.1e-33 113.6 0.3 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase CCDC50_N PF15295.6 CDS29074.1 - 0.0074 16.4 8.8 0.44 10.7 1.4 3.1 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 50 N-terminus DEAD PF00270.29 CDS29076.1 - 1.4e-48 164.9 0.0 4.8e-48 163.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS29076.1 - 4.5e-31 107.5 0.1 4.8e-30 104.2 0.4 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS29076.1 - 0.0055 16.7 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NUP50 PF08911.11 CDS29077.1 - 3.9e-13 49.8 1.0 3.9e-13 49.8 1.0 2.2 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 CDS29077.1 - 3.2e-09 37.1 0.0 9.5e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 RanBP1 domain Presenilin PF01080.17 CDS29078.1 - 4.4 5.9 5.2 6.6 5.4 5.2 1.2 1 0 0 1 1 1 0 Presenilin NDUFA12 PF05071.16 CDS29080.2 - 2.1e-08 34.9 0.2 2.1e-08 34.9 0.2 2.8 2 2 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ATG16 PF08614.11 CDS29080.2 - 3.9e-05 24.0 95.5 0.00071 19.9 14.0 7.8 3 1 3 7 7 6 4 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDS29080.2 - 0.00044 19.2 87.0 0.025 13.5 11.5 6.4 4 1 1 6 6 6 4 Spc7 kinetochore protein DUF4763 PF15960.5 CDS29080.2 - 0.002 17.5 7.2 0.002 17.5 7.2 5.9 4 1 1 6 6 5 1 Domain of unknown function (DUF4763) Fez1 PF06818.15 CDS29080.2 - 0.0061 17.0 16.8 0.0061 17.0 16.8 5.6 2 1 2 5 5 5 2 Fez1 BRE1 PF08647.11 CDS29080.2 - 0.0069 16.4 10.6 0.0069 16.4 10.6 8.6 6 3 1 8 8 7 1 BRE1 E3 ubiquitin ligase Cut12 PF11500.8 CDS29080.2 - 0.014 15.3 1.4 0.014 15.3 1.4 5.6 5 1 0 6 6 6 0 Spindle pole body formation-associated protein Filament PF00038.21 CDS29080.2 - 0.025 14.1 74.8 0.031 13.9 27.5 6.2 3 2 1 4 4 4 0 Intermediate filament protein DUF2935 PF11155.8 CDS29080.2 - 0.026 14.9 3.7 42 4.5 2.8 4.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) SNCAIP_SNCA_bd PF16700.5 CDS29080.2 - 0.036 13.8 2.0 0.9 9.3 0.2 3.0 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain NPV_P10 PF05531.12 CDS29080.2 - 0.24 11.9 38.7 1.2 9.6 1.3 8.5 8 2 1 9 9 8 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 CDS29080.2 - 0.46 10.0 75.8 2.3 7.7 9.3 5.8 4 1 2 6 6 6 0 Mechanosensitive ion channel porin domain DUF4618 PF15397.6 CDS29080.2 - 0.51 9.7 60.6 0.083 12.3 5.2 6.8 5 2 1 6 6 6 0 Domain of unknown function (DUF4618) AAA_13 PF13166.6 CDS29080.2 - 0.52 8.9 60.7 0.044 12.4 14.2 4.2 2 1 0 3 3 3 0 AAA domain DUF1664 PF07889.12 CDS29080.2 - 0.6 10.2 47.1 1.5 8.8 1.8 7.7 6 1 3 9 9 9 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 CDS29080.2 - 1.1 8.7 83.2 0.075 12.5 22.5 5.8 3 2 2 5 5 5 0 Hyaluronan mediated motility receptor N-terminal HAP1_N PF04849.13 CDS29080.2 - 1.1 8.4 78.3 0.022 14.0 12.8 6.1 5 2 1 6 6 6 0 HAP1 N-terminal conserved region Atg14 PF10186.9 CDS29080.2 - 2.2 7.3 80.3 3.6 6.6 3.1 6.8 1 1 5 7 7 7 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 CDS29080.2 - 3.3 7.7 95.8 0.51 10.4 15.3 7.1 5 1 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 CDS29080.2 - 5.4 6.8 86.4 0.24 11.2 0.4 6.2 4 1 0 5 5 5 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 CDS29080.2 - 5.5 6.4 77.3 0.081 12.4 12.2 5.5 3 1 3 6 6 6 0 Golgin subfamily A member 5 IFT57 PF10498.9 CDS29080.2 - 7.3 5.4 58.7 4.1 6.3 0.4 5.8 3 1 2 5 5 5 0 Intra-flagellar transport protein 57 PCAF_N PF06466.11 CDS29081.2 - 3.1e-48 164.5 2.8 3.1e-48 164.5 2.8 1.7 2 0 0 2 2 2 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 CDS29081.2 - 1.5e-21 76.2 0.1 4.4e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 CDS29081.2 - 3.9e-06 27.1 0.0 8.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDS29081.2 - 0.00042 20.3 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDS29081.2 - 0.0033 17.8 0.2 0.0068 16.8 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0054 PF02130.17 CDS29081.2 - 0.12 12.1 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 RNase_HII PF01351.18 CDS29082.2 - 2.4e-48 164.6 0.0 3.1e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Fea1 PF07692.11 CDS29082.2 - 0.039 13.0 0.2 0.056 12.5 0.2 1.1 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein BTD PF09270.10 CDS29083.2 - 1e-50 171.9 0.2 1.2e-44 152.3 0.0 2.4 1 1 1 2 2 2 2 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 CDS29083.2 - 2.1e-49 168.0 0.5 4.6e-49 166.9 0.1 1.8 2 0 0 2 2 2 1 LAG1, DNA binding Peptidase_C12 PF01088.21 CDS29084.1 - 1.7e-61 207.7 0.0 1.9e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 GPI2 PF06432.11 CDS29085.2 - 2.4e-35 122.3 11.6 6e-27 94.8 8.7 2.0 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase EamA PF00892.20 CDS29085.2 - 0.5 10.5 12.3 0.17 12.1 4.7 2.4 2 0 0 2 2 2 0 EamA-like transporter family fn3 PF00041.21 CDS29086.1 - 0.0035 17.7 0.0 0.0083 16.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ComGG PF14173.6 CDS29086.1 - 0.019 15.4 0.1 0.04 14.3 0.1 1.6 1 1 0 1 1 1 0 ComG operon protein 7 Glycogen_syn PF05693.13 CDS29088.2 - 0 1038.3 0.0 0 1037.9 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CDS29088.2 - 1.3e-06 28.0 0.0 0.00022 20.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDS29088.2 - 7.1e-06 26.5 0.0 0.003 18.0 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CDS29088.2 - 3.1e-05 23.8 0.2 0.0003 20.6 0.2 2.4 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 CDS29088.2 - 0.0014 18.6 0.2 0.011 15.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 DnaJ PF00226.31 CDS29089.2 - 2.6e-24 85.1 0.4 2.6e-24 85.1 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain Anoctamin PF04547.12 CDS29090.1 - 8.5e-81 272.1 2.6 1.1e-80 271.7 2.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel bZIP_2 PF07716.15 CDS29091.2 - 6.5e-08 32.5 10.9 6.5e-08 32.5 10.9 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS29091.2 - 0.0038 17.3 9.6 0.0076 16.3 9.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor HeLo PF14479.6 CDS29091.2 - 0.0061 16.4 3.4 0.0085 15.9 3.4 1.3 1 1 0 1 1 1 1 Prion-inhibition and propagation EDR1 PF14381.6 CDS29091.2 - 0.047 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 TMA7 PF09072.10 CDS29091.2 - 0.38 11.6 1.8 0.74 10.7 1.8 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 bZIP_2 PF07716.15 CDS29092.2 - 3.7e-08 33.3 11.6 3.7e-08 33.3 11.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS29092.2 - 3.2e-06 27.2 7.1 3.2e-06 27.2 7.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor Tropomyosin_1 PF12718.7 CDS29092.2 - 0.011 15.9 8.1 0.4 10.8 0.3 2.6 2 1 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.9 CDS29092.2 - 0.076 13.3 4.8 0.62 10.4 0.3 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 CDS29092.2 - 0.64 9.8 4.7 0.19 11.5 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 CDS29093.1 - 3.5e-07 30.2 12.7 5.7e-07 29.5 12.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS29093.1 - 8.1e-07 29.0 10.1 1.4e-06 28.3 10.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor LLC1 PF14945.6 CDS29093.1 - 0.0023 18.5 1.1 0.0037 17.8 0.9 1.4 1 1 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-CpG_bind_C PF12269.8 CDS29093.1 - 0.072 12.9 1.8 0.1 12.3 1.8 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain GLE1 PF07817.13 CDS29093.1 - 0.14 11.4 0.4 0.2 10.8 0.4 1.1 1 0 0 1 1 1 0 GLE1-like protein Exostosin PF03016.15 CDS29094.2 - 1.2e-49 169.2 1.6 1.7e-49 168.7 0.1 2.0 3 0 0 3 3 3 1 Exostosin family Glyco_transf_64 PF09258.10 CDS29094.2 - 1.6e-38 132.4 0.1 5.8e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain STPPase_N PF16891.5 CDS29095.2 - 2e-20 73.0 0.1 3.8e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CDS29095.2 - 2.7e-11 44.4 0.0 4.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RCC1 PF00415.18 CDS29096.2 - 6.4e-25 87.5 1.1 3.7e-12 46.7 0.0 3.5 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDS29096.2 - 7.7e-19 67.0 13.3 9.1e-11 41.3 2.0 2.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat SET PF00856.28 CDS29097.2 - 1.1e-16 61.7 0.1 7.5e-16 59.0 0.0 2.3 2 1 0 2 2 2 1 SET domain FAM199X PF15814.5 CDS29097.2 - 0.029 13.4 6.7 0.05 12.6 6.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF104 PF01954.16 CDS29097.2 - 0.1 13.0 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF104 EF-hand_7 PF13499.6 CDS29100.1 - 1.4e-20 73.5 1.4 1.3e-12 48.0 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS29100.1 - 2.7e-20 70.3 1.3 1.6e-06 27.3 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDS29100.1 - 1.2e-17 62.3 2.5 1.4e-05 24.7 0.2 4.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CDS29100.1 - 2.5e-12 45.7 1.3 0.00065 19.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDS29100.1 - 7.4e-11 41.7 2.6 1.4e-05 24.8 0.3 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CDS29100.1 - 0.0014 18.5 0.7 3.4 7.7 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS29100.1 - 0.0027 18.0 0.9 0.87 9.9 0.1 3.5 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Homeodomain PF00046.29 CDS29100.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain Peptidase_M17 PF00883.21 CDS29101.2 - 1.3e-57 195.5 0.2 1.9e-57 194.9 0.2 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Tetraspanin PF00335.20 CDS29103.1 - 3.1e-13 50.0 9.1 3.7e-13 49.7 9.1 1.0 1 0 0 1 1 1 1 Tetraspanin family Oxidored_q2 PF00420.24 CDS29103.1 - 0.01 15.4 1.5 0.031 13.9 1.5 1.7 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF308 PF03729.13 CDS29103.1 - 0.015 15.6 2.3 0.067 13.5 0.1 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3185 PF11381.8 CDS29103.1 - 0.043 13.8 0.3 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) YtpI PF14007.6 CDS29103.1 - 0.13 12.5 4.2 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 YtpI-like protein Tetraspanin PF00335.20 CDS29104.2 - 2.3e-16 60.2 17.5 2.8e-16 59.9 17.5 1.0 1 0 0 1 1 1 1 Tetraspanin family Corona_S2 PF01601.16 CDS29104.2 - 1.4 7.3 6.8 2.4 6.6 6.8 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DDE_1 PF03184.19 CDS29106.2 - 1.2e-09 38.1 0.0 2.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 CDS29106.2 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 CDS29106.2 - 0.02 14.9 0.0 0.07 13.2 0.0 2.0 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain PHD PF00628.29 CDS29106.2 - 0.13 12.1 3.6 0.3 11.0 3.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 CDS29106.2 - 0.25 11.4 2.7 0.53 10.3 2.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Ribosomal_L13 PF00572.18 CDS29107.2 - 1.4e-20 73.8 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Aminotran_3 PF00202.21 CDS29109.2 - 2.9e-121 404.9 0.0 3.4e-121 404.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDS29109.2 - 0.00033 20.0 0.0 0.00067 18.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II RT_RNaseH PF17917.1 CDS29111.2 - 1.7e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS29111.2 - 0.062 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase SNF2_N PF00176.23 CDS29116.1 - 4.8e-62 209.7 0.0 1.6e-61 207.9 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS29116.1 - 8.6e-19 67.9 0.0 4e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain YojJ PF10372.9 CDS29116.1 - 0.12 12.4 1.3 0.44 10.7 1.3 1.9 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Baculo_PEP_C PF04513.12 CDS29116.1 - 0.52 10.3 5.1 0.27 11.3 1.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.10 CDS29116.1 - 5.9 7.0 5.9 1.9 8.6 0.9 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_S5 PF00333.20 CDS29117.1 - 7.5e-30 102.7 1.6 8.6e-30 102.5 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDS29117.1 - 1.7e-25 88.2 0.0 2.9e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CDS29117.1 - 2.1 9.0 12.6 3.9 8.1 12.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HEV_ORF1 PF02444.16 CDS29118.2 - 0.042 14.4 3.4 0.72 10.4 1.3 3.0 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Sulfotransfer_3 PF13469.6 CDS29121.1 - 3e-37 129.1 0.0 5.1e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CDS29121.1 - 1.2e-10 41.4 0.1 6.6e-10 38.9 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CDS29121.1 - 0.00015 21.7 0.2 0.00053 19.9 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain CBM_21 PF03370.13 CDS29123.2 - 1.9e-17 63.5 0.3 3.2e-17 62.7 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDS29123.2 - 0.0092 16.5 0.1 0.026 15.1 0.1 1.7 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) COesterase PF00135.28 CDS29124.2 - 3.5e-29 102.1 0.0 1.1e-27 97.2 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS29124.2 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDS29124.2 - 0.038 13.5 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase_Tyr PF07714.17 CDS29127.2 - 5.9e-74 248.6 0.0 6.2e-63 212.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS29127.2 - 2.1e-31 109.3 0.0 5.4e-28 98.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Furin-like PF00757.20 CDS29127.2 - 9e-24 84.1 33.1 8.3e-22 77.7 19.7 2.8 2 1 0 2 2 2 2 Furin-like cysteine rich region Recep_L_domain PF01030.24 CDS29127.2 - 3.3e-23 81.9 0.0 4.9e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain fn3 PF00041.21 CDS29127.2 - 2.1e-08 34.4 6.5 0.014 15.7 0.2 5.6 5 0 0 5 5 5 2 Fibronectin type III domain Kinase-like PF14531.6 CDS29127.2 - 0.0003 20.2 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pur_ac_phosph_N PF16656.5 CDS29127.2 - 0.016 15.7 1.2 3.4 8.3 0.1 3.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Syndecan PF01034.20 CDS29127.2 - 0.036 14.0 4.0 1.4 8.8 2.6 2.4 2 0 0 2 2 2 0 Syndecan domain GF_recep_IV PF14843.6 CDS29127.2 - 4.2 7.2 33.5 10 5.9 25.0 3.0 2 1 0 2 2 2 0 Growth factor receptor domain IV YEATS PF03366.16 CDS29128.2 - 1.6e-17 63.2 0.8 3.2e-17 62.3 0.8 1.5 1 0 0 1 1 1 1 YEATS family HLH PF00010.26 CDS29129.2 - 1.6e-18 66.4 0.2 1.6e-18 66.4 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ESSS PF10183.9 CDS29129.2 - 1.8e-05 24.9 0.0 5.6e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GTP_EFTU PF00009.27 CDS29131.2 - 2e-18 66.6 0.0 3.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS29131.2 - 0.0031 17.6 0.1 0.0088 16.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF3350 PF11830.8 CDS29131.2 - 0.28 11.5 1.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) CAP PF00188.26 CDS29133.2 - 0.52 11.2 7.6 0.11 13.4 4.0 2.1 2 1 0 2 2 2 0 Cysteine-rich secretory protein family DUF4717 PF15838.5 CDS29136.2 - 0.076 13.0 0.3 0.18 11.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4717) Ribosomal_60s PF00428.19 CDS29138.1 - 1.5e-22 79.9 17.4 6.4e-21 74.7 17.4 2.0 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF1476 PF07345.11 CDS29138.1 - 0.033 14.5 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Ric8 PF10165.9 CDS29139.1 - 2.5e-94 316.9 0.1 2.9e-94 316.7 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn YjeF_N PF03853.15 CDS29141.1 - 3e-17 63.0 0.0 3.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus FERM_M PF00373.18 CDS29142.2 - 6.7e-27 94.2 0.0 2.8e-26 92.2 0.0 2.2 1 0 0 1 1 1 1 FERM central domain Talin_middle PF09141.10 CDS29142.2 - 9.8e-21 74.5 1.8 9.8e-21 74.5 1.8 11.1 11 2 0 11 11 11 4 Talin, middle domain I_LWEQ PF01608.17 CDS29142.2 - 4.9e-14 52.8 99.2 3.8e-09 36.9 9.7 14.8 11 4 4 16 16 16 5 I/LWEQ domain FERM_N PF09379.10 CDS29142.2 - 2e-09 37.3 0.1 6.3e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain VBS PF08913.10 CDS29142.2 - 4.6e-05 23.9 34.2 0.0019 18.6 0.2 8.8 7 1 1 8 8 8 3 Vinculin Binding Site IRS PF02174.17 CDS29142.2 - 0.017 15.0 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 PTB domain (IRS-1 type) SipA_VBS PF17985.1 CDS29142.2 - 0.033 14.1 4.1 8.2 6.5 0.1 5.2 5 0 0 5 5 5 0 SipA vinculin binding site MtrB PF05440.12 CDS29142.2 - 0.24 11.8 1.1 14 6.1 0.0 3.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Exo_endo_phos_2 PF14529.6 CDS29145.1 - 0.049 13.5 0.1 0.082 12.7 0.1 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DAHP_synth_2 PF01474.16 CDS29146.1 - 0.079 11.5 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Class-II DAHP synthetase family BEN PF10523.9 CDS29147.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 BEN domain Aminotran_5 PF00266.19 CDS29149.1 - 2.1e-07 30.2 0.0 4.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V PTH2 PF01981.16 CDS29150.1 - 7.6e-43 145.5 0.0 9.7e-43 145.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AsnC_trans_reg PF01037.21 CDS29150.1 - 0.00054 19.9 0.1 0.0011 18.9 0.0 1.5 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain NOC3p PF07540.11 CDS29151.1 - 1.5e-25 89.5 0.1 9.4e-25 86.9 0.1 2.5 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 CDS29151.1 - 5.2e-17 62.4 0.2 2.4e-16 60.3 0.2 2.2 1 0 0 1 1 1 1 CBF/Mak21 family RanGAP1_C PF07834.11 CDS29151.1 - 0.075 12.6 0.9 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 RanGAP1 C-terminal domain DUF1981 PF09324.10 CDS29151.1 - 0.28 11.0 2.6 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) D123 PF07065.14 CDS29152.1 - 1.6e-84 283.7 1.2 2e-84 283.4 1.2 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 CDS29152.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 RRM_1 PF00076.22 CDS29153.1 - 5.9e-39 131.7 1.5 1.3e-15 57.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS29153.1 - 2.7e-05 24.2 0.8 0.18 11.9 0.0 3.7 3 2 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CDS29153.1 - 0.016 14.8 0.0 0.53 9.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 CDS29153.1 - 0.022 15.0 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_occluded PF16842.5 CDS29153.1 - 0.026 14.4 0.1 0.58 10.1 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif CSTF2_hinge PF14327.6 CDS29154.1 - 6.7e-28 97.0 2.4 6.7e-28 97.0 2.4 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CDS29154.1 - 5.3e-22 77.4 0.0 8.7e-22 76.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CDS29154.1 - 2.9e-16 58.8 4.9 2.9e-15 55.5 3.3 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CDS29154.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 CDS29154.1 - 0.21 11.7 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Tubulin PF00091.25 CDS29155.1 - 4.6e-57 193.4 0.0 1.3e-56 191.9 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS29155.1 - 5e-35 120.4 0.0 9.3e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CDS29155.1 - 0.049 12.8 0.0 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Tubulin like NRDD PF13597.6 CDS29155.1 - 0.097 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase 7tm_1 PF00001.21 CDS29156.1 - 3e-12 46.4 12.4 3.9e-12 46.1 12.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS29156.1 - 8.3e-07 28.6 27.0 9.5e-06 25.1 1.4 3.2 2 1 1 3 3 3 3 Serpentine type 7TM GPCR chemoreceptor Srw NADHdh_A3 PF14987.6 CDS29156.1 - 0.053 13.8 0.4 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Baculo_11_kDa PF06143.11 CDS29156.1 - 0.15 11.7 0.4 0.63 9.6 0.4 2.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4014 PF13198.6 CDS29156.1 - 1.2 9.5 7.1 1.1 9.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Voltage_CLC PF00654.20 CDS29156.1 - 1.8 7.7 8.4 6.3 5.9 8.3 1.8 1 1 0 1 1 1 0 Voltage gated chloride channel CitMHS PF03600.16 CDS29156.1 - 3.2 6.9 5.9 85 2.2 6.6 2.4 1 1 0 1 1 1 0 Citrate transporter Troponin PF00992.20 CDS29158.1 - 1.6e-35 122.3 18.8 1.6e-35 122.3 18.8 3.1 2 1 1 3 3 3 2 Troponin Med5 PF08689.10 CDS29159.1 - 0.3 8.9 4.4 0.34 8.7 4.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 C_Hendra PF16821.5 CDS29159.1 - 1.9 8.3 9.3 2.5 8.0 9.3 1.1 1 0 0 1 1 1 0 C protein from hendra and measles viruses EVI2A PF05399.11 CDS29159.1 - 3.3 7.2 7.8 4.1 6.9 7.8 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Transposase_1 PF01359.18 CDS29160.1 - 5.7e-13 48.5 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) PNP_UDP_1 PF01048.20 CDS29161.1 - 6e-12 45.3 0.1 2.4e-11 43.3 0.1 1.7 1 1 1 2 2 2 1 Phosphorylase superfamily Promethin PF16015.5 CDS29162.1 - 0.31 11.0 2.0 0.76 9.7 2.0 1.5 1 0 0 1 1 1 0 Promethin EGF PF00008.27 CDS29165.1 - 3.7e-19 68.7 70.1 2.3e-06 27.8 6.6 7.7 6 1 0 6 6 6 5 EGF-like domain Ank_2 PF12796.7 CDS29165.1 - 1.3e-16 61.0 0.0 2.3e-09 37.7 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Notch PF00066.17 CDS29165.1 - 3.3e-15 56.3 16.3 1.4e-09 38.3 4.2 6.5 7 0 0 7 7 7 2 LNR domain Ank_5 PF13857.6 CDS29165.1 - 2.3e-10 40.5 0.0 0.00076 19.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) hEGF PF12661.7 CDS29165.1 - 1.6e-05 25.4 15.2 0.00015 22.3 3.3 9.4 10 1 0 10 10 10 4 Human growth factor-like EGF Ank PF00023.30 CDS29165.1 - 3.3e-05 24.1 0.0 0.044 14.3 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 CDS29165.1 - 6.4e-05 23.0 0.1 0.012 16.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 CDS29165.1 - 0.0011 19.5 0.1 2.6 8.7 0.0 4.0 3 1 0 4 4 4 1 Ankyrin repeats (many copies) EGF_2 PF07974.13 CDS29165.1 - 0.0086 16.4 0.1 0.0086 16.4 0.1 8.3 7 2 0 7 7 7 4 EGF-like domain POPLD PF08170.12 CDS29165.1 - 2.6 8.5 5.7 0.85 10.0 2.1 2.2 2 0 0 2 2 2 0 POPLD (NUC188) domain DUF1330 PF07045.11 CDS29168.1 - 3.9e-05 23.9 0.0 0.012 16.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) 7tm_1 PF00001.21 CDS29170.1 - 1.5e-19 70.3 20.7 1.6e-19 70.3 19.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS29170.1 - 6.9e-14 51.9 19.5 8.3e-12 45.0 19.5 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDS29170.1 - 6.9e-07 29.2 23.8 3.4e-06 26.9 23.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CDS29170.1 - 1.6e-05 24.4 19.3 2.7e-05 23.7 18.9 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Dynein_light PF01221.18 CDS29171.1 - 4.5e-39 132.7 1.2 5e-39 132.5 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Swm2 PF17083.5 CDS29171.1 - 0.022 14.8 0.2 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Vps53_N PF04100.12 CDS29172.1 - 3.6e-89 299.4 8.1 5.1e-88 295.6 8.1 2.2 1 1 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CDS29172.1 - 0.0015 17.9 4.4 0.0033 16.8 2.6 2.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CDS29172.1 - 0.0016 18.3 0.3 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4754 PF15946.5 CDS29172.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) DUF5082 PF16888.5 CDS29172.1 - 0.29 11.4 4.2 1.1 9.6 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CDS29172.1 - 1.9 9.0 10.1 1.1 9.7 1.6 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 CDS29173.1 - 0.076 13.3 1.9 0.4 11.0 1.9 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein Seadorna_VP6 PF07407.11 CDS29173.1 - 0.4 9.6 2.5 0.44 9.4 2.5 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein PCRF PF03462.18 CDS29173.1 - 2.2 8.1 5.9 3.1 7.6 5.9 1.4 1 0 0 1 1 1 0 PCRF domain LRR_9 PF14580.6 CDS29174.1 - 1.1e-14 54.3 10.4 1.5e-13 50.6 5.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CDS29174.1 - 5.3e-13 48.9 26.1 2.9e-05 24.3 3.8 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS29174.1 - 1.4e-06 27.9 23.5 0.00013 21.7 12.7 3.3 3 1 1 4 4 4 3 Leucine rich repeat YgaB PF14182.6 CDS29174.1 - 0.014 15.7 0.1 0.014 15.7 0.1 2.8 4 0 0 4 4 4 0 YgaB-like protein Fib_alpha PF08702.10 CDS29174.1 - 0.032 14.4 1.0 0.16 12.2 0.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LRR_6 PF13516.6 CDS29174.1 - 0.29 11.3 15.8 0.51 10.5 0.3 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Dynein_light PF01221.18 CDS29175.1 - 4.1e-22 78.3 0.6 4.4e-22 78.2 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CDS29175.1 - 0.069 13.8 0.1 0.075 13.7 0.1 1.2 1 0 0 1 1 1 0 Ground-like domain DUF2465 PF10239.9 CDS29176.1 - 8.9e-75 251.9 0.0 1.4e-74 251.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Ldl_recept_a PF00057.18 CDS29176.1 - 2.8e-08 33.8 34.9 8.1e-05 22.8 5.4 4.2 4 0 0 4 4 4 3 Low-density lipoprotein receptor domain class A DUF1752 PF08550.10 CDS29176.1 - 0.025 14.4 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) RIO1 PF01163.22 CDS29177.1 - 6.9e-56 188.8 0.0 2.5e-55 187.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CDS29177.1 - 0.0059 15.4 0.0 0.0059 15.4 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Neur_chan_memb PF02932.16 CDS29177.1 - 0.48 10.4 2.7 0.77 9.8 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 CDS29177.1 - 8 4.6 22.5 12 4.1 22.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4770 PF15994.5 CDS29177.1 - 9.4 6.4 7.4 22 5.2 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Carb_kinase PF01256.17 CDS29178.1 - 2.4e-54 184.4 0.0 3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CDS29178.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PAS_3 PF08447.12 CDS29179.1 - 4.6e-17 62.1 0.8 2.8e-12 46.8 0.1 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CDS29179.1 - 4.1e-14 52.6 0.5 1.7e-11 44.2 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CDS29179.1 - 8.7e-13 48.3 0.0 3.2e-07 30.3 0.0 3.4 2 1 1 3 3 3 2 PAS fold HLH PF00010.26 CDS29179.1 - 1.3e-06 28.3 0.5 3.4e-06 26.9 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 CDS29179.1 - 0.011 16.0 0.0 0.085 13.1 0.0 2.4 3 0 0 3 3 3 0 PAS domain RabGAP-TBC PF00566.18 CDS29181.2 - 3.9e-36 124.7 0.3 8.2e-36 123.7 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 CDS29181.2 - 1.6e-05 25.3 0.0 3.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 PH domain BLOC1_2 PF10046.9 CDS29181.2 - 0.063 13.6 0.3 0.16 12.3 0.3 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HATPase_c_4 PF13749.6 CDS29181.2 - 0.089 12.9 0.0 2.6 8.2 0.0 2.7 3 0 0 3 3 3 0 Putative ATP-dependent DNA helicase recG C-terminal Ku PF02735.16 CDS29182.1 - 0.47 10.1 6.7 0.22 11.2 4.2 1.7 1 1 0 1 1 1 0 Ku70/Ku80 beta-barrel domain RabGAP-TBC PF00566.18 CDS29183.1 - 4.7e-05 23.2 0.4 7.3e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PQQ_3 PF13570.6 CDS29183.1 - 0.0011 19.4 0.0 6.9 7.3 0.0 3.7 3 0 0 3 3 3 2 PQQ-like domain WD40_like PF17005.5 CDS29183.1 - 0.0011 18.3 0.3 1 8.7 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain dbPDZ_assoc PF16610.5 CDS29183.1 - 0.011 15.9 1.4 0.022 15.0 1.4 1.5 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Ets PF00178.22 CDS29184.1 - 1.6e-31 108.6 0.6 3.3e-31 107.6 0.6 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.16 CDS29184.1 - 1e-06 28.6 0.4 3e-06 27.1 0.2 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain GABP-alpha PF11620.8 CDS29184.1 - 1.5e-06 28.3 0.1 2.6e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 GA-binding protein alpha chain SRF-TF PF00319.18 CDS29185.1 - 2.4e-17 62.2 0.3 4.6e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HTH_48 PF17906.1 CDS29186.1 - 8.8e-10 38.6 0.1 1.7e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase zf-C2H2_2 PF12756.7 CDS29187.1 - 2.6e-17 63.0 12.1 3.1e-12 46.7 0.7 4.0 3 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDS29187.1 - 3.6e-06 27.2 5.4 3.6e-06 27.2 5.4 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS29187.1 - 1.1e-05 25.5 7.2 1.1e-05 25.5 7.2 4.4 5 1 0 5 5 5 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 CDS29187.1 - 0.00084 19.2 0.3 0.0029 17.4 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) zf-DBF PF07535.12 CDS29187.1 - 0.0019 18.2 3.8 0.0019 18.2 3.8 3.0 3 0 0 3 3 3 1 DBF zinc finger AKAP95 PF04988.12 CDS29187.1 - 0.0055 17.0 4.9 0.098 12.9 0.6 2.7 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_aberr PF17017.5 CDS29187.1 - 0.0095 16.1 0.9 0.26 11.4 0.3 2.5 2 0 0 2 2 2 1 Aberrant zinc-finger C1_2 PF03107.16 CDS29187.1 - 0.61 10.4 8.3 0.12 12.7 0.6 3.2 4 0 0 4 4 4 0 C1 domain zf-C2H2_4 PF13894.6 CDS29187.1 - 0.84 10.6 20.5 0.11 13.5 1.8 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDS29187.1 - 4.2 7.4 7.1 6.8 6.7 0.6 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type cNMP_binding PF00027.29 CDS29188.1 - 1.5e-12 47.4 0.0 1.1e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SHMT PF00464.19 CDS29190.1 - 3.9e-165 549.3 0.0 6.6e-165 548.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Nbas_N PF15492.6 CDS29191.1 - 4.9e-09 35.9 0.8 1.5e-08 34.4 0.6 1.8 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Rdx PF10262.9 CDS29192.1 - 1.7e-10 40.9 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family NDUF_B8 PF05821.11 CDS29192.1 - 0.18 11.6 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Ank_2 PF12796.7 CDS29193.1 - 2.2e-128 419.1 23.9 2.8e-13 50.3 0.1 15.8 4 3 12 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29193.1 - 2.9e-105 343.4 41.2 4.7e-12 46.2 0.1 20.2 14 4 6 20 20 20 19 Ankyrin repeats (many copies) Ank PF00023.30 CDS29193.1 - 3.2e-104 337.2 56.3 2.7e-07 30.7 0.2 26.0 26 1 0 26 26 26 23 Ankyrin repeat Ank_3 PF13606.6 CDS29193.1 - 1.7e-90 286.0 46.5 4.6e-05 23.5 0.1 27.2 27 1 0 27 27 27 21 Ankyrin repeat Ank_5 PF13857.6 CDS29193.1 - 5.2e-90 294.3 48.8 1.9e-09 37.6 0.2 23.2 10 4 15 25 25 25 22 Ankyrin repeats (many copies) DUF3449 PF11931.8 CDS29194.1 - 2.6e-76 255.5 0.4 5.6e-76 254.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 CDS29194.1 - 2.5e-24 84.7 0.1 7.5e-24 83.2 0.1 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 CDS29194.1 - 2.2e-22 79.4 5.6 2.2e-22 79.4 5.6 2.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 CDS29194.1 - 1.7e-10 40.6 0.3 4.6e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain ARID PF01388.21 CDS29194.1 - 0.039 14.6 0.2 0.33 11.7 0.0 2.4 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain PI-PLC-C1 PF16670.5 CDS29194.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent zf-C2H2_4 PF13894.6 CDS29194.1 - 0.14 13.1 0.1 0.47 11.4 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 CDS29194.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-CCCH_4 PF18044.1 CDS29195.1 - 0.00027 20.6 2.9 0.00083 19.1 2.9 1.9 1 1 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDS29195.1 - 0.023 15.2 5.8 0.11 13.1 5.8 2.3 1 1 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CDS29195.1 - 0.033 14.3 1.7 0.033 14.3 1.7 2.6 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CDS29195.1 - 0.063 13.2 6.8 1.1 9.3 1.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TMEM119 PF15724.5 CDS29196.1 - 0.16 12.0 0.1 5.1 7.1 0.0 2.1 2 0 0 2 2 2 0 TMEM119 family NABP PF07990.12 CDS29199.1 - 0.028 14.0 1.1 0.031 13.8 1.1 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ABC2_membrane PF01061.24 CDS29201.1 - 8e-44 149.6 23.1 8e-44 149.6 23.1 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDS29201.1 - 8.4e-31 107.3 0.0 1.4e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CDS29201.1 - 3.8e-05 23.7 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDS29201.1 - 7.6e-05 23.2 0.1 0.00067 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 CDS29201.1 - 0.00032 20.2 0.2 0.007 15.8 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDS29201.1 - 0.00063 19.6 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDS29201.1 - 0.0065 16.2 0.3 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDS29201.1 - 0.01 15.9 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CDS29201.1 - 0.015 14.9 0.3 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDS29201.1 - 0.019 15.3 0.1 0.073 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDS29201.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDS29201.1 - 0.1 13.0 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 CDS29201.1 - 0.12 12.9 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CDS29201.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 CDS29201.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF1440 PF07274.12 CDS29201.1 - 1.8 8.9 7.9 13 6.1 6.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1440) DUF2070 PF09843.9 CDS29201.1 - 2.4 6.3 15.4 3.5 5.8 15.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RPN6_N PF18055.1 CDS29202.1 - 3.7e-33 114.3 0.3 1.2e-32 112.7 0.3 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CDS29202.1 - 1e-18 67.7 0.0 2.6e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain Tox-ODYAM1 PF15642.6 CDS29202.1 - 0.0011 18.1 2.1 0.0018 17.4 0.8 1.8 2 0 0 2 2 2 1 Toxin in Odyssella and Amoebophilus DDRGK PF09756.9 CDS29202.1 - 0.0088 15.7 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.6 CDS29202.1 - 0.011 16.0 3.2 0.019 15.2 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat N_Asn_amidohyd PF14736.6 CDS29202.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase WD40 PF00400.32 CDS29203.1 - 2.5e-15 56.6 7.7 0.0011 19.7 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS29203.1 - 6.7e-06 26.3 0.0 2.5 8.4 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS29203.1 - 0.00038 19.5 0.0 0.07 12.1 0.0 3.2 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LsmAD PF06741.13 CDS29203.1 - 0.59 10.7 6.0 1.7 9.3 6.0 1.8 1 0 0 1 1 1 0 LsmAD domain UDPG_MGDP_dh_N PF03721.14 CDS29204.1 - 1.5e-47 161.6 0.2 2.5e-47 160.9 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CDS29204.1 - 2.7e-26 91.6 0.0 4.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CDS29204.1 - 1.3e-21 77.0 0.0 4.5e-19 68.8 0.0 2.7 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CDS29204.1 - 0.0065 16.6 0.0 0.95 9.6 0.0 3.5 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 CDS29204.1 - 0.045 13.7 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3756 PF12581.8 CDS29204.1 - 0.38 10.7 3.0 0.23 11.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Zip PF02535.22 CDS29205.1 - 2e-82 277.1 6.9 8.3e-56 189.6 4.8 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter HisKA_4TM PF16926.5 CDS29205.1 - 0.024 14.2 1.4 0.055 13.0 1.4 1.5 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Feld-I_B PF09252.10 CDS29207.1 - 0.076 13.0 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Allergen Fel d I-B chain PAXX PF15384.6 CDS29207.1 - 0.11 12.2 2.4 0.11 12.1 1.2 1.6 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 ZapB PF06005.12 CDS29207.1 - 0.61 10.6 6.7 0.3 11.6 0.6 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Ig_3 PF13927.6 CDS29208.1 - 5e-08 33.4 1.6 0.0006 20.4 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CDS29208.1 - 1.8e-06 28.2 1.4 0.0008 19.7 0.1 3.1 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CDS29208.1 - 3.7e-06 27.0 0.8 0.00025 21.1 0.2 2.8 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CDS29208.1 - 6.5e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 CDS29208.1 - 0.0097 15.9 0.0 0.42 10.7 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain HA2 PF04408.23 CDS29209.1 - 7.3e-14 52.0 0.1 3.7e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDS29209.1 - 1e-12 48.4 0.1 4.7e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS29209.1 - 1.2e-11 44.6 0.0 3.7e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS29209.1 - 0.016 15.2 0.0 0.17 11.9 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ubiquitin PF00240.23 CDS29210.1 - 4e-07 29.7 0.0 1.4e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS29210.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Reticulon PF02453.17 CDS29210.1 - 0.01 15.8 0.7 0.025 14.6 0.7 1.6 1 0 0 1 1 1 0 Reticulon Mab-21 PF03281.14 CDS29211.1 - 1.6e-93 313.2 0.0 2.3e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein HRM PF02793.22 CDS29211.1 - 0.19 12.1 0.2 1 9.7 0.1 2.1 2 0 0 2 2 2 0 Hormone receptor domain NOGCT PF08155.11 CDS29214.1 - 6.7e-18 64.4 0.8 1.2e-17 63.6 0.8 1.4 1 0 0 1 1 1 1 NOGCT (NUC087) domain ThiF PF00899.21 CDS29216.2 - 1.8e-59 201.1 0.0 3.1e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CDS29216.2 - 1.4e-14 54.4 0.0 3.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CDS29216.2 - 1.1e-05 25.5 0.0 0.09 12.7 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 CDS29216.2 - 0.0023 18.4 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDS29216.2 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 CDS29216.2 - 0.014 15.6 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PHM7_cyt PF14703.6 CDS29217.2 - 0.002 18.4 0.4 0.0026 18.0 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Fmp27_WPPW PF10359.9 CDS29217.2 - 0.027 13.4 0.7 0.033 13.0 0.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NDK PF00334.19 CDS29218.1 - 2.6e-28 98.7 0.0 3e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FTR1 PF03239.14 CDS29219.1 - 0.33 10.1 3.1 0.18 10.9 0.8 1.6 1 1 1 2 2 2 0 Iron permease FTR1 family DUF5316 PF17247.2 CDS29219.1 - 1.6 8.8 5.8 1.5 8.9 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5316) DA1-like PF12315.8 CDS29220.1 - 0.19 11.1 0.4 0.34 10.3 0.4 1.6 1 1 0 1 1 1 0 Protein DA1 RhoGAP PF00620.27 CDS29221.2 - 0.00012 21.9 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain LPP PF04728.13 CDS29222.2 - 0.18 12.2 0.2 0.48 10.8 0.1 1.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Malic_M PF03949.15 CDS29227.2 - 2e-79 266.5 0.0 2.4e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain LPP PF04728.13 CDS29229.2 - 0.22 12.0 0.4 0.47 10.9 0.1 1.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Malic_M PF03949.15 CDS29230.2 - 8.3e-77 257.9 0.0 9.7e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Malic_M PF03949.15 CDS29232.1 - 8.9e-13 48.1 0.0 9.4e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain PDZ PF00595.24 CDS29233.1 - 3.9e-10 39.9 0.1 3.9e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 PDZ domain TPR_1 PF00515.28 CDS29235.2 - 2.5e-14 52.4 1.5 1.1e-05 25.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS29235.2 - 3.1e-09 36.3 3.7 0.0078 16.3 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS29235.2 - 0.00026 20.6 0.3 0.0005 19.7 0.3 1.5 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 CDS29235.2 - 0.0021 18.3 3.9 0.0027 18.0 0.3 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS29235.2 - 0.0047 17.0 0.7 7.6 7.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS29235.2 - 0.012 16.2 6.1 0.84 10.3 0.2 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS29235.2 - 0.017 15.4 0.4 0.14 12.5 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS29235.2 - 0.073 13.9 5.1 12 7.0 0.3 4.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDS29235.2 - 0.098 13.2 0.1 0.098 13.2 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 CDS29238.1 - 5.9e-05 23.3 7.5 0.27 11.7 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDS29238.1 - 7.7e-05 22.9 0.7 7.7e-05 22.9 0.7 3.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type DUF3268 PF11672.8 CDS29238.1 - 0.0073 16.6 5.3 3.8 7.9 0.0 4.0 4 0 0 4 4 4 1 zinc-finger-containing domain zf-C2H2_4 PF13894.6 CDS29238.1 - 0.014 16.2 0.5 0.014 16.2 0.5 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS29238.1 - 0.042 13.9 0.6 0.042 13.9 0.6 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.12 CDS29238.1 - 0.3 11.4 3.4 6.1 7.2 0.6 3.1 2 0 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.6 CDS29238.1 - 0.7 10.5 3.6 7.1 7.2 1.0 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 CDS29238.1 - 2.6 7.9 5.2 22 4.9 0.2 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDS29238.1 - 6.9 6.9 7.1 4.4 7.5 0.3 3.1 2 1 0 2 2 2 0 Zinc ribbon domain AKAP95 PF04988.12 CDS29239.1 - 0.01 16.0 0.5 7 6.9 0.0 2.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_ZHX PF18387.1 CDS29239.1 - 0.071 12.8 1.0 21 4.9 0.3 3.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CDS29239.1 - 0.18 12.1 8.1 0.63 10.4 0.2 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding APC_u5 PF16630.5 CDS29239.1 - 0.24 12.4 6.3 4.4 8.4 0.7 3.7 3 0 0 3 3 3 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs OrsD PF12013.8 CDS29239.1 - 0.25 11.8 5.0 6.4 7.3 0.3 2.7 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 CDS29239.1 - 0.28 11.5 2.6 9.9 6.6 0.1 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 CDS29239.1 - 0.46 10.4 8.5 1.8 8.5 0.0 3.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) LIG3_BRCT PF16759.5 CDS29239.1 - 0.58 10.5 2.0 10 6.5 0.4 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain zf-H2C2_5 PF13909.6 CDS29239.1 - 0.79 9.5 9.5 0.36 10.6 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rhodanese_C PF12368.8 CDS29239.1 - 6.2 7.3 9.2 34 4.9 0.2 3.9 4 0 0 4 4 4 0 Rhodanase C-terminal DUF4950 PF16308.5 CDS29239.1 - 6.4 6.7 14.7 2.4 8.1 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4950) zf-C2H2_4 PF13894.6 CDS29240.1 - 5.2e-11 42.4 14.5 0.0031 18.2 1.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS29240.1 - 2e-10 40.5 16.4 0.00013 22.3 0.6 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS29240.1 - 1.7e-08 34.5 14.9 2.1e-05 24.7 1.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-MYST PF17772.1 CDS29240.1 - 0.00026 20.5 6.6 0.18 11.4 0.1 3.9 3 1 1 4 4 4 2 MYST family zinc finger domain zf-BED PF02892.15 CDS29240.1 - 0.00074 19.5 6.4 2.1 8.5 1.5 3.4 2 1 1 3 3 3 2 BED zinc finger DUF2197 PF09963.9 CDS29240.1 - 0.0026 18.0 5.5 1.5 9.1 0.1 3.3 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2197) zf-Di19 PF05605.12 CDS29240.1 - 0.0037 17.5 0.7 0.0037 17.5 0.7 2.5 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CDS29240.1 - 0.0099 16.1 12.9 0.051 13.9 1.1 3.7 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.16 CDS29240.1 - 0.022 14.9 4.4 9.6 6.5 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf-RRPl_C4 PF17026.5 CDS29240.1 - 0.055 13.6 2.7 0.25 11.5 1.3 2.4 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 CDS29240.1 - 0.12 12.5 3.3 0.23 11.6 0.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 CDS29240.1 - 0.13 12.3 11.3 3 8.0 1.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CDS29240.1 - 0.13 12.6 7.1 0.78 10.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C4_ClpX PF06689.13 CDS29240.1 - 0.16 11.9 2.2 20 5.2 0.1 3.1 3 0 0 3 3 3 0 ClpX C4-type zinc finger zf-FPG_IleRS PF06827.14 CDS29240.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.6 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS FYDLN_acid PF09538.10 CDS29240.1 - 0.44 11.2 1.2 19 6.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-HYPF PF07503.12 CDS29240.1 - 1 9.2 11.6 8.8 6.2 0.5 2.8 2 1 0 2 2 2 0 HypF finger zinc_ribbon_9 PF14369.6 CDS29240.1 - 1.2 9.4 4.6 1.6 9.1 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon PHD PF00628.29 CDS29240.1 - 2 8.3 5.2 32 4.5 1.5 2.9 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_SprT PF17283.2 CDS29240.1 - 2.4 8.1 6.4 15 5.6 1.1 2.5 1 1 2 3 3 3 0 SprT-like zinc ribbon domain HNH PF01844.23 CDS29240.1 - 2.8 8.2 6.1 56 4.0 0.1 3.4 4 0 0 4 4 3 0 HNH endonuclease zinc_ribbon_10 PF10058.9 CDS29240.1 - 4.1 7.2 6.0 33 4.3 0.0 3.0 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf_UBZ PF18439.1 CDS29240.1 - 4.2 7.0 5.3 7 6.3 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger NPV_P10 PF05531.12 CDS29241.1 - 0.041 14.3 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C2H2_4 PF13894.6 CDS29243.2 - 1.1 10.3 4.4 5.5 8.1 4.4 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS29244.1 - 2.8e-20 71.5 19.4 0.00014 22.1 4.6 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29244.1 - 4.5e-16 58.2 16.1 0.0026 18.4 0.0 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS29244.1 - 4e-13 49.1 23.0 3.8e-05 23.9 0.3 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDS29244.1 - 3.7e-09 36.2 17.5 0.013 15.3 2.9 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type XPA_N PF01286.18 CDS29244.1 - 4.1e-06 26.7 6.0 2.6 8.2 0.3 4.3 4 0 0 4 4 4 1 XPA protein N-terminal zf_UBZ PF18439.1 CDS29244.1 - 3.3e-05 23.4 6.6 1.3 8.7 0.1 4.3 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CDS29244.1 - 0.00073 19.6 11.2 1 9.5 0.6 3.9 3 1 1 4 4 4 2 Zinc ribbon domain ADK_lid PF05191.14 CDS29244.1 - 0.00092 19.1 12.1 0.24 11.4 0.4 3.7 2 2 1 3 3 3 2 Adenylate kinase, active site lid ZZ PF00569.17 CDS29244.1 - 0.0047 16.7 9.4 2.8 7.8 0.0 4.5 4 1 0 4 4 4 1 Zinc finger, ZZ type CpXC PF14353.6 CDS29244.1 - 0.0051 16.8 9.6 2 8.4 2.7 3.8 1 1 3 4 4 4 2 CpXC protein zf-trcl PF13451.6 CDS29244.1 - 0.021 14.7 8.0 9.2 6.3 0.5 4.1 4 0 0 4 4 4 0 Probable zinc-ribbon domain zf-RING_7 PF02591.15 CDS29244.1 - 0.054 13.7 7.6 0.62 10.3 0.0 3.9 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-LYAR PF08790.11 CDS29244.1 - 0.063 13.2 0.3 0.063 13.2 0.3 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 CDS29244.1 - 0.083 13.2 11.5 0.046 14.0 4.0 2.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 CDS29244.1 - 0.15 12.8 13.7 2.9 8.6 5.2 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Desulfoferrod_N PF06397.12 CDS29244.1 - 0.24 11.1 0.2 0.24 11.1 0.2 4.1 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zinc-ribbons_6 PF07191.12 CDS29244.1 - 0.3 11.1 11.0 4.5 7.3 4.3 3.0 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_6 PF13912.6 CDS29244.1 - 0.38 10.8 30.6 1.5 8.9 0.1 4.8 5 1 0 5 5 4 0 C2H2-type zinc finger Nudix_N_2 PF14803.6 CDS29244.1 - 0.6 10.1 7.8 17 5.5 0.1 3.9 4 0 0 4 4 4 0 Nudix N-terminal Rubredoxin_2 PF18073.1 CDS29244.1 - 0.7 9.7 14.1 8.1 6.3 0.3 4.1 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-C2H2_3 PF13878.6 CDS29244.1 - 0.71 9.7 8.8 17 5.3 0.0 4.1 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO TF_Zn_Ribbon PF08271.12 CDS29244.1 - 0.72 9.4 7.6 6.7 6.3 0.1 3.8 4 0 0 4 4 4 0 TFIIB zinc-binding zf-AN1 PF01428.16 CDS29244.1 - 1 9.6 16.9 7.3 6.8 1.1 4.3 4 1 0 4 4 4 0 AN1-like Zinc finger zf-C4_Topoisom PF01396.19 CDS29244.1 - 1.2 8.9 9.1 15 5.5 0.1 3.9 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-RRN7 PF11781.8 CDS29244.1 - 1.4 8.7 9.8 2.2 8.0 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-ribbon_3 PF13248.6 CDS29244.1 - 1.4 8.4 11.8 7.1 6.2 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-ACC PF17848.1 CDS29244.1 - 1.8 8.7 14.8 3.5 7.8 0.2 4.2 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-C2HC_2 PF13913.6 CDS29244.1 - 2.4 8.1 9.1 19 5.3 0.0 4.4 4 0 0 4 4 3 0 zinc-finger of a C2HC-type Tox-PL-2 PF15643.6 CDS29244.1 - 2.8 8.1 8.1 1.2 9.3 0.2 3.2 1 1 3 4 4 4 0 Papain fold toxin 2 zf-BED PF02892.15 CDS29244.1 - 3.5 7.7 27.9 1.1 9.3 0.9 4.2 2 2 2 4 4 4 0 BED zinc finger zf-C2HE PF16278.5 CDS29244.1 - 3.5 8.1 19.6 0.18 12.3 3.7 3.7 1 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger TFIIS_C PF01096.18 CDS29244.1 - 4.7 7.1 10.6 33 4.5 0.3 4.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-met PF12874.7 CDS29244.1 - 5.5 7.5 16.1 1.9 9.0 0.2 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type OrfB_Zn_ribbon PF07282.11 CDS29244.1 - 7.3 6.6 13.2 10 6.1 1.8 3.6 2 2 1 3 3 3 0 Putative transposase DNA-binding domain Mito_carr PF00153.27 CDS29245.1 - 1e-62 208.0 2.7 1.4e-21 76.2 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.20 CDS29246.1 - 3.5e-34 117.5 0.0 4.9e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS29246.1 - 0.0044 16.6 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CDS29246.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.7 1 1 1 2 2 2 0 Rit1 DUSP-like domain Rootletin PF15035.6 CDS29247.1 - 7.7e-46 156.5 50.7 1.1e-45 156.0 28.8 13.5 5 2 7 12 12 12 2 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 CDS29248.1 - 0.00027 20.1 5.4 0.00027 20.1 5.4 2.9 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 CDS29248.1 - 0.17 11.4 35.3 0.55 9.8 35.2 2.0 1 1 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 CDS29248.1 - 1.2 9.2 61.4 3 7.9 14.3 4.4 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MRP-S34 PF16053.5 CDS29250.1 - 4.1e-35 120.2 0.0 6.2e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 MRI PF15325.6 CDS29251.1 - 0.056 14.5 0.1 0.08 14.0 0.1 1.3 1 1 0 1 1 1 0 Modulator of retrovirus infection Pkinase PF00069.25 CDS29252.1 - 1.5e-72 244.2 0.0 2.2e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29252.1 - 4.2e-44 150.8 0.0 6.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29252.1 - 3.2e-09 36.5 0.0 7.3e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDS29252.1 - 6e-05 22.7 0.4 0.00012 21.8 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDS29252.1 - 0.00042 19.7 0.3 0.00078 18.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS29252.1 - 0.0061 15.6 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain UBA PF00627.31 CDS29252.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain TBP PF00352.21 CDS29253.1 - 2.4e-53 178.0 0.3 1.9e-25 88.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Ribosomal_L37ae PF01780.19 CDS29253.1 - 7.8e-37 125.2 10.0 1.2e-36 124.6 10.0 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_2 PF03107.16 CDS29253.1 - 0.0073 16.6 2.9 1.5 9.2 2.9 2.3 1 1 0 1 1 1 1 C1 domain Zn_Tnp_IS1595 PF12760.7 CDS29253.1 - 0.016 15.1 3.9 0.036 14.0 3.9 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 CDS29253.1 - 0.039 14.3 2.1 0.085 13.3 2.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 CDS29253.1 - 0.56 10.0 4.6 1.7 8.5 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CDS29253.1 - 1 8.8 3.3 26 4.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 CDS29253.1 - 3.5 7.7 6.2 3.1e+02 1.5 6.2 2.4 1 1 0 1 1 1 0 BED zinc finger Tmemb_9 PF05434.11 CDS29254.1 - 1.2e-40 138.8 0.2 1.2e-40 138.8 0.2 1.5 2 0 0 2 2 2 1 TMEM9 Gemini_mov PF01708.16 CDS29254.1 - 0.18 11.6 5.4 0.16 11.8 3.9 1.7 1 1 0 1 1 1 0 Geminivirus putative movement protein BTB_2 PF02214.22 CDS29256.1 - 3.3e-21 75.5 0.3 8.6e-21 74.1 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CDS29256.1 - 8e-09 35.1 2.5 1.3e-08 34.4 2.5 1.4 1 0 0 1 1 1 1 Ion transport protein Shal-type PF11601.8 CDS29256.1 - 1.7e-06 27.4 3.5 1.7e-06 27.4 3.5 1.6 2 0 0 2 2 2 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 CDS29256.1 - 2.3e-05 24.5 0.1 4.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain ARPC4 PF05856.12 CDS29257.1 - 6.4e-79 263.4 4.0 7.1e-79 263.2 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 CDS29257.1 - 0.045 13.9 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Sm_like domain HTH_Tnp_Tc3_1 PF11427.8 CDS29257.1 - 0.046 13.6 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase L51_S25_CI-B8 PF05047.16 CDS29258.1 - 4.7e-11 42.4 0.1 9.9e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DDE_1 PF03184.19 CDS29258.1 - 0.0053 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4023 PF13215.6 CDS29258.1 - 0.28 11.2 0.9 0.78 9.8 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Cadherin PF00028.17 CDS29259.2 - 1.2e-67 224.4 0.7 1.7e-11 44.4 0.0 10.5 8 3 0 8 8 8 7 Cadherin domain Cadherin_3 PF16184.5 CDS29259.2 - 1.4e-09 37.9 2.4 0.049 13.6 0.1 6.3 6 1 1 7 7 7 3 Cadherin-like Cadherin_2 PF08266.12 CDS29259.2 - 6.3e-08 32.3 0.0 0.13 12.1 0.1 4.8 4 0 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 CDS29259.2 - 0.0097 16.2 0.1 5.2 7.4 0.0 4.4 5 0 0 5 5 5 1 RET Cadherin like domain 1 TMEM154 PF15102.6 CDS29259.2 - 0.04 13.8 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Glyco_hydro_15 PF00723.21 CDS29262.1 - 1.2e-87 294.6 0.0 1.6e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Myb_DNA-binding PF00249.31 CDS29263.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CDS29263.1 - 0.00029 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CDS29263.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Peptidase_C2 PF00648.21 CDS29264.1 - 1.4e-49 168.8 0.0 3e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDS29264.1 - 1.6e-21 77.0 0.0 5.8e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 CDS29264.1 - 6.2e-13 48.9 0.0 2.8e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 C2 domain 14-3-3 PF00244.20 CDS29264.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 14-3-3 protein WD40_4 PF16300.5 CDS29264.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Type of WD40 repeat Telomere_res PF16684.5 CDS29267.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Telomere resolvase Kelch_6 PF13964.6 CDS29269.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Y_phosphatase PF00102.27 CDS29272.2 - 6.1e-10 39.1 0.0 7.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDS29272.2 - 0.26 11.2 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family BTB_2 PF02214.22 CDS29275.1 - 8.6e-18 64.5 0.0 2e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDS29275.1 - 0.00095 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Neurexophilin PF06312.12 CDS29275.1 - 0.036 13.5 0.2 0.076 12.5 0.2 1.5 1 0 0 1 1 1 0 Neurexophilin AAA PF00004.29 CDS29276.1 - 6.3e-36 123.7 0.0 1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS29276.1 - 5.5e-07 29.3 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDS29276.1 - 3.6e-06 27.5 0.8 0.00023 21.6 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CDS29276.1 - 1.2e-05 25.3 0.1 0.0001 22.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS29276.1 - 8.2e-05 22.9 1.0 0.071 13.4 0.1 2.8 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 CDS29276.1 - 0.00036 20.6 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDS29276.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CDS29276.1 - 0.00059 19.3 0.0 0.041 13.3 0.0 2.6 1 1 1 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 CDS29276.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CDS29276.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 CDS29276.1 - 0.0053 16.4 0.2 0.43 10.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDS29276.1 - 0.0095 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDS29276.1 - 0.014 14.8 0.1 0.039 13.3 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CDS29276.1 - 0.025 14.7 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CDS29276.1 - 0.027 14.9 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 CDS29276.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 CDS29276.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 CDS29276.1 - 0.038 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDS29276.1 - 0.049 13.4 0.0 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDS29276.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CDS29276.1 - 0.072 13.0 0.2 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 CDS29276.1 - 0.089 12.1 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 CDS29276.1 - 0.09 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 CDS29276.1 - 0.11 12.3 0.1 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activ_2 PF14532.6 CDS29276.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CDS29276.1 - 0.12 12.3 0.2 0.63 9.9 0.1 2.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CDS29276.1 - 0.13 12.0 0.0 0.45 10.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDS29276.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDS29276.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 CDS29276.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CD20 PF04103.15 CDS29277.1 - 1.8e-06 28.2 10.9 1.8e-06 28.2 10.9 2.9 3 0 0 3 3 3 1 CD20-like family TMEM171 PF15471.6 CDS29277.1 - 0.054 12.5 1.6 0.14 11.1 1.6 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 PMT_4TMC PF16192.5 CDS29277.1 - 0.1 12.2 0.6 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase RhoGEF PF00621.20 CDS29278.1 - 8e-22 78.4 0.9 1.8e-21 77.2 0.0 2.1 2 1 0 2 2 2 1 RhoGEF domain KH_1 PF00013.29 CDS29280.1 - 1.2e-12 47.5 0.0 1e-10 41.3 0.0 2.7 3 0 0 3 3 3 1 KH domain KH_10 PF17905.1 CDS29280.1 - 6.2e-10 39.4 0.8 1.5e-05 25.3 0.4 3.4 2 1 0 2 2 2 2 GLD-3 KH domain 5 KH_4 PF13083.6 CDS29280.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 KH domain Pkinase_Tyr PF07714.17 CDS29281.2 - 3.4e-79 265.8 0.9 3.5e-74 249.4 0.5 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS29281.2 - 1e-37 130.0 0.8 5.8e-36 124.2 0.2 2.5 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.6 CDS29281.2 - 3.2e-13 49.6 54.9 1.8e-05 24.5 17.3 4.0 1 1 3 4 4 4 4 Growth factor receptor domain IV Furin-like PF00757.20 CDS29281.2 - 2.7e-06 27.3 63.9 8e-05 22.6 10.1 4.0 2 1 2 4 4 4 3 Furin-like cysteine rich region Kinase-like PF14531.6 CDS29281.2 - 0.0034 16.7 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDS29281.2 - 0.0044 15.8 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS29281.2 - 0.0053 16.7 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS29281.2 - 0.0075 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS29281.2 - 0.027 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS29281.2 - 0.2 11.2 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family COQ7 PF03232.13 CDS29283.1 - 2.1e-46 157.8 0.0 2.3e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Acetyltransf_16 PF05301.11 CDS29284.1 - 3.2e-32 111.7 2.0 5e-32 111.1 2.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 CDS29284.1 - 0.00061 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS29284.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDS29284.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ARGLU PF15346.6 CDS29285.1 - 1.7e-08 34.5 41.6 1.7e-08 34.5 41.6 2.9 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 MTS PF05175.14 CDS29286.1 - 3.3e-08 33.3 0.0 3.3e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CDS29286.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDS29286.1 - 0.021 15.5 0.0 0.037 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDS29286.1 - 0.021 15.5 0.0 0.037 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CDS29286.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2012 PF09430.10 CDS29287.1 - 2.2e-25 89.2 0.0 3.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CDS29287.1 - 0.00087 19.5 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 CDS29287.1 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Pkinase PF00069.25 CDS29288.2 - 4.9e-64 216.2 0.1 5.7e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29288.2 - 1.4e-32 113.0 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS29288.2 - 0.00097 18.2 0.6 0.0014 17.6 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CDS29288.2 - 0.015 15.2 1.5 0.37 10.7 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS29288.2 - 0.015 14.1 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CDS29288.2 - 0.057 12.8 0.4 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS29288.2 - 0.073 12.7 0.4 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 RIO1 family TPR_1 PF00515.28 CDS29289.1 - 3e-16 58.5 0.7 0.00021 21.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS29289.1 - 2.7e-13 48.9 0.5 0.00051 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS29289.1 - 7.4e-05 22.7 1.5 0.26 11.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS29289.1 - 0.00019 21.4 0.9 0.0071 16.4 0.2 3.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CDS29289.1 - 0.00062 20.4 4.7 0.23 12.4 0.9 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS29289.1 - 0.001 19.3 4.6 0.16 12.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3597 PF12200.8 CDS29289.1 - 0.016 15.8 0.1 0.041 14.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) TPR_9 PF13371.6 CDS29289.1 - 0.058 13.5 2.0 1 9.6 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CH PF00307.31 CDS29290.2 - 3.2e-05 24.1 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Exo_endo_phos_2 PF14529.6 CDS29291.1 - 8.2e-13 48.3 0.8 1.2e-12 47.7 0.1 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS29291.1 - 0.0036 16.8 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UCR_14kD PF02271.16 CDS29292.1 - 6.1e-29 99.9 0.1 7.6e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Casc1_N PF15927.5 CDS29292.1 - 0.031 14.0 0.2 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ank PF00023.30 CDS29293.1 - 1.9e-23 81.8 1.7 1.2e-08 35.0 0.0 4.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 CDS29293.1 - 2.3e-23 82.3 1.8 5.8e-11 42.7 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS29293.1 - 4.7e-21 75.2 1.1 3.9e-16 59.4 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS29293.1 - 1.2e-19 70.1 0.0 9.5e-12 44.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29293.1 - 1.2e-17 62.2 5.9 2.4e-07 30.5 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Tctex-1 PF03645.13 CDS29294.1 - 2.4e-34 117.7 1.3 3e-34 117.4 1.3 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF3860 PF12976.7 CDS29294.1 - 0.13 12.3 0.8 1.6 8.8 0.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) RNA_pol_3_Rpc31 PF11705.8 CDS29295.1 - 0.41 10.9 13.1 0.63 10.3 13.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AdoHcyase PF05221.17 CDS29297.1 - 8.2e-135 448.7 0.0 6.4e-74 248.8 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CDS29297.1 - 4.8e-83 277.1 1.9 7.4e-83 276.5 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDS29297.1 - 2.3e-08 33.6 0.0 5.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDS29297.1 - 6.9e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 CDS29297.1 - 0.00029 21.2 0.2 0.00066 20.1 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDS29297.1 - 0.00068 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 CDS29297.1 - 0.0027 17.9 0.1 0.0055 16.9 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 CDS29297.1 - 0.012 14.3 0.0 0.049 12.4 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.19 CDS29297.1 - 0.026 13.8 0.3 0.087 12.1 0.3 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 CDS29297.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pkinase PF00069.25 CDS29298.1 - 4.8e-46 157.3 0.0 7.9e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29298.1 - 5.7e-31 107.7 0.0 1.9e-29 102.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PTEN_C2 PF10409.9 CDS29298.1 - 2e-22 79.4 0.1 3.5e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Kdo PF06293.14 CDS29298.1 - 0.00057 19.3 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 CDS29298.1 - 0.00097 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Kinase-like PF14531.6 CDS29298.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDS29298.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain 7tm_1 PF00001.21 CDS29299.2 - 1.6e-49 168.7 25.8 1.9e-49 168.4 25.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS29299.2 - 7.3e-14 51.8 24.9 1.1e-13 51.2 24.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDS29299.2 - 3.8e-12 46.1 23.6 1.3e-11 44.4 9.4 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS29299.2 - 2.1e-10 40.7 30.7 1.8e-09 37.6 29.5 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDS29299.2 - 1e-05 25.4 18.5 1.3e-05 25.1 18.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srv PF10323.9 CDS29299.2 - 3.8e-05 23.2 25.4 0.0012 18.3 25.2 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Sru PF10322.9 CDS29299.2 - 0.017 14.4 21.7 0.35 10.1 2.7 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru Mito_carr PF00153.27 CDS29300.1 - 9.2e-13 47.9 0.2 1.3e-07 31.5 0.1 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3437 PF11919.8 CDS29302.1 - 1.3e-11 44.2 0.0 5.4e-11 42.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) zf-MIZ PF02891.20 CDS29303.2 - 4.5e-19 67.9 5.5 1.2e-18 66.6 5.5 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CDS29303.2 - 1.6e-06 27.8 4.5 4.2e-06 26.5 4.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PBP1_TM PF14812.6 CDS29303.2 - 0.0019 18.5 0.7 0.0082 16.5 0.7 2.1 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PINIT PF14324.6 CDS29303.2 - 0.0023 18.3 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 PINIT domain Herpes_LMP1 PF05297.11 CDS29303.2 - 0.97 8.6 3.1 1.7 7.8 3.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Laminin_EGF PF00053.24 CDS29303.2 - 6.4 7.0 14.2 2 8.6 1.1 3.8 3 1 0 3 3 3 0 Laminin EGF domain EF-hand_1 PF00036.32 CDS29304.2 - 6e-05 22.3 0.0 0.0047 16.4 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDS29304.2 - 9.3e-05 22.1 0.0 0.00081 19.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 CDS29304.2 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDS29304.2 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair GPHH PF16905.5 CDS29304.2 - 0.027 14.2 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Transposase_1 PF01359.18 CDS29305.1 - 7.7e-11 41.7 0.1 1.1e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Transposase (partial DDE domain) Ion_trans PF00520.31 CDS29307.1 - 0.0031 16.8 0.3 0.0044 16.3 0.3 1.2 1 0 0 1 1 1 1 Ion transport protein Lon_C PF05362.13 CDS29308.1 - 6.6e-65 218.5 0.0 2.9e-56 190.3 0.0 2.8 2 0 0 2 2 2 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CDS29308.1 - 8.2e-31 107.5 0.4 1.5e-30 106.7 0.4 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CDS29308.1 - 4.4e-23 82.1 0.0 9.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDS29308.1 - 3.1e-09 36.9 0.0 6.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CDS29308.1 - 1.2e-06 28.3 0.0 3.1e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 CDS29308.1 - 2.2e-06 28.2 2.4 2.7e-05 24.6 0.0 3.3 3 1 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 CDS29308.1 - 6.1e-06 26.1 0.0 0.00025 20.9 0.0 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 CDS29308.1 - 9e-06 24.8 0.1 2.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 CDS29308.1 - 1.1e-05 25.6 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDS29308.1 - 1.8e-05 25.0 0.9 0.0014 18.9 0.0 3.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 CDS29308.1 - 0.00094 19.2 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDS29308.1 - 0.0039 17.6 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CDS29308.1 - 0.004 16.9 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 CDS29308.1 - 0.0069 16.3 0.0 0.039 13.9 0.0 2.1 1 1 0 1 1 1 1 NACHT domain TIP49 PF06068.13 CDS29308.1 - 0.011 15.0 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CDS29308.1 - 0.014 15.9 0.2 0.049 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 CDS29308.1 - 0.015 14.4 0.0 0.039 13.0 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 CDS29308.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDS29308.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDS29308.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDS29308.1 - 0.037 13.8 2.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDS29308.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 CDS29308.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase AAA_33 PF13671.6 CDS29308.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDS29308.1 - 0.082 12.8 0.1 2 8.3 0.0 2.8 2 1 1 3 3 2 0 NTPase ABC_tran PF00005.27 CDS29308.1 - 0.088 13.3 0.5 0.68 10.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 CDS29308.1 - 0.095 12.6 3.3 1.1 9.1 0.0 3.0 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CDS29308.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.0 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 CDS29308.1 - 0.11 11.9 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CDS29308.1 - 0.12 11.5 1.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_3 PF07726.11 CDS29308.1 - 0.14 12.1 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CDS29308.1 - 0.17 12.2 0.0 0.58 10.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF759 PF05537.11 CDS29308.1 - 0.29 10.0 4.9 3.8 6.3 1.2 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) MIEAP PF16026.5 CDS29308.1 - 0.51 10.5 2.1 0.59 10.3 0.1 2.1 3 0 0 3 3 2 0 Mitochondria-eating protein Calponin PF00402.18 CDS29309.1 - 3.1e-61 202.6 34.9 1.9e-13 49.8 0.9 5.4 5 0 0 5 5 5 5 Calponin family repeat CH PF00307.31 CDS29309.1 - 2e-20 73.0 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain P34-Arc PF04045.14 CDS29310.1 - 3.2e-88 295.5 0.1 4.1e-88 295.1 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc G-alpha PF00503.20 CDS29312.1 - 3.7e-118 394.8 5.8 3.2e-116 388.3 1.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 CDS29312.1 - 1.7e-13 50.4 0.9 1.1e-09 38.0 0.1 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS29312.1 - 0.0093 16.0 1.2 32 4.7 0.0 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDS29312.1 - 0.035 13.4 4.4 0.39 10.0 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CDS29312.1 - 0.045 13.2 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Rota_NSP4 PF01452.16 CDS29312.1 - 0.05 13.3 2.3 0.1 12.3 1.9 1.7 1 1 0 1 1 1 0 Rotavirus non structural protein Roc PF08477.13 CDS29312.1 - 0.071 13.3 0.1 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5345 PF17280.2 CDS29312.1 - 0.42 10.6 10.3 0.56 10.2 1.8 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DHHC PF01529.20 CDS29313.1 - 3.2e-37 127.6 7.8 3.2e-37 127.6 7.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase 7tm_7 PF08395.12 CDS29313.1 - 0.027 13.7 0.6 0.027 13.7 0.6 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF2975 PF11188.8 CDS29313.1 - 0.047 13.6 0.5 0.047 13.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Ribosomal_L40e PF01020.17 CDS29313.1 - 0.051 13.5 2.7 0.13 12.2 2.7 1.7 1 0 0 1 1 1 0 Ribosomal L40e family Frizzled PF01534.17 CDS29314.1 - 2.3e-126 421.3 15.8 3.3e-126 420.8 15.8 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDS29314.1 - 5.3e-32 110.7 6.0 1.2e-31 109.6 6.0 1.6 1 0 0 1 1 1 1 Fz domain Transmemb_17 PF09799.9 CDS29314.1 - 0.093 13.3 0.0 0.093 13.3 0.0 3.2 3 1 0 3 3 3 0 Predicted membrane protein rve_3 PF13683.6 CDS29317.1 - 0.079 12.7 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CDS29319.1 - 7.8e-16 58.3 0.1 9.4e-15 54.7 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TraF_2 PF13729.6 CDS29319.1 - 0.17 11.2 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein PP2C_2 PF13672.6 CDS29321.1 - 0.098 12.3 0.8 0.13 11.9 0.8 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C bVLRF1 PF18826.1 CDS29323.1 - 1.2e-30 106.4 0.9 1e-29 103.3 0.0 2.7 3 0 0 3 3 3 1 bacteroidetes VLRF1 release factor VATC PF18716.1 CDS29323.1 - 1.9e-12 46.8 1.0 1.9e-12 46.8 1.0 2.1 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 CDS29323.1 - 0.0093 16.3 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.7 CDS29323.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DDE_Tnp_IS66_C PF13817.6 CDS29323.1 - 0.022 15.0 0.1 13 6.1 0.0 3.3 3 0 0 3 3 3 0 IS66 C-terminal element DNApol_Exo PF18136.1 CDS29323.1 - 0.25 10.4 3.9 0.6 9.2 3.9 1.6 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain zf-C2H2_jaz PF12171.8 CDS29323.1 - 0.53 10.6 3.3 1.3 9.4 3.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dimerisation PF08100.11 CDS29323.1 - 0.61 10.1 1.7 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 Dimerisation domain SVIP PF15811.5 CDS29323.1 - 1.4 9.4 8.5 0.25 11.8 1.1 3.0 2 0 0 2 2 2 0 Small VCP/p97-interacting protein FancD2 PF14631.6 CDS29323.1 - 2.5 5.4 4.7 4.5 4.6 4.7 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ndc1_Nup PF09531.10 CDS29323.1 - 3.3 6.3 7.0 5.9 5.5 7.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_1 PF00515.28 CDS29324.1 - 1.7e-59 195.4 34.3 9.7e-07 28.4 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CDS29324.1 - 1.6e-50 165.2 25.5 5.8e-06 26.0 0.7 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 CDS29324.1 - 7.6e-36 119.3 27.9 6.8e-05 22.8 0.3 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 CDS29324.1 - 1.2e-32 111.3 11.8 1.1e-08 34.6 0.1 6.8 6 2 2 8 8 8 4 TPR repeat STI1 PF17830.1 CDS29324.1 - 1.6e-30 104.8 0.5 2.8e-14 52.8 0.3 3.2 2 0 0 2 2 2 2 STI1 domain TPR_14 PF13428.6 CDS29324.1 - 2.5e-27 93.2 7.7 0.0015 19.2 0.0 9.3 5 3 6 11 11 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CDS29324.1 - 2.2e-25 88.9 8.6 8.6e-05 23.0 0.0 6.7 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 CDS29324.1 - 3.4e-23 81.7 17.1 1.7e-08 34.6 0.0 7.4 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDS29324.1 - 1.9e-22 79.6 7.5 0.00028 21.5 0.0 6.4 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 CDS29324.1 - 6.8e-21 73.1 19.1 0.00018 21.6 0.1 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDS29324.1 - 2.5e-16 59.2 17.5 0.00017 22.0 0.1 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDS29324.1 - 8.7e-14 51.4 0.0 0.002 18.2 0.0 5.8 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 CDS29324.1 - 2.8e-12 45.7 12.1 0.19 11.8 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDS29324.1 - 2.9e-08 33.3 9.8 0.94 9.4 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS29324.1 - 1.1e-07 32.0 18.3 0.00023 21.3 0.2 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 CDS29324.1 - 6.7e-06 25.7 26.0 0.0024 17.3 7.9 4.7 2 2 2 4 4 4 3 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 CDS29324.1 - 6e-05 22.1 13.1 1.3 7.8 0.1 5.4 2 2 2 6 6 6 3 NMDA receptor-regulated protein 1 BTAD PF03704.17 CDS29324.1 - 0.00037 21.0 0.9 8.2 6.8 0.1 4.3 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CDS29324.1 - 0.0015 18.5 16.1 1.1 9.4 0.0 7.5 9 0 0 9 9 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 CDS29324.1 - 0.0017 17.8 0.0 0.11 11.8 0.0 2.5 1 1 1 2 2 2 1 MalT-like TPR region TPR_20 PF14561.6 CDS29324.1 - 0.0079 16.5 12.4 0.082 13.2 0.1 4.4 3 1 2 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 CDS29324.1 - 0.0092 15.7 12.7 0.4 10.4 1.6 5.0 2 2 3 6 6 6 1 26S proteasome subunit RPN7 FAT PF02259.23 CDS29324.1 - 0.013 14.7 3.8 1.2 8.2 0.2 2.7 2 0 0 2 2 2 0 FAT domain alpha-hel2 PF14456.6 CDS29324.1 - 0.042 13.2 1.9 0.085 12.1 1.9 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF3856 PF12968.7 CDS29324.1 - 0.054 13.6 8.4 2.3 8.3 0.9 4.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) MAS20 PF02064.15 CDS29324.1 - 0.14 12.2 4.4 4.8 7.3 0.1 3.3 3 0 0 3 3 3 0 MAS20 protein import receptor Alkyl_sulf_dimr PF14863.6 CDS29324.1 - 0.25 11.8 3.8 55 4.2 0.0 4.1 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation YfiO PF13525.6 CDS29324.1 - 0.27 10.9 11.7 1.2 8.8 0.2 3.4 3 2 1 4 4 4 0 Outer membrane lipoprotein NYD-SP12_N PF15015.6 CDS29324.1 - 0.38 9.1 4.1 7 4.9 0.0 2.9 3 0 0 3 3 3 0 Spermatogenesis-associated, N-terminal SAE2 PF08573.10 CDS29324.1 - 0.65 11.1 6.2 0.5 11.5 1.0 2.9 3 0 0 3 3 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus MIT PF04212.18 CDS29324.1 - 0.97 9.6 0.0 0.97 9.6 0.0 5.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CDS29324.1 - 1.7 8.1 4.3 10 5.7 0.0 4.0 5 0 0 5 5 5 0 SHNi-TPR Bravo_FIGEY PF13882.6 CDS29325.2 - 1.2e-10 42.6 0.0 4.1e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 Bravo-like intracellular region RRM_1 PF00076.22 CDS29327.1 - 1e-34 118.2 0.0 8.4e-17 60.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PrsW-protease PF13367.6 CDS29327.1 - 0.067 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease RRM_occluded PF16842.5 CDS29327.1 - 0.082 12.8 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CDS29327.1 - 0.18 11.8 0.1 28 4.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif PH PF00169.29 CDS29328.2 - 0.017 15.6 0.0 0.095 13.2 0.0 2.2 2 0 0 2 2 2 0 PH domain ORMDL PF04061.14 CDS29329.1 - 9.8e-49 164.6 1.4 1.7e-48 163.9 1.4 1.4 1 0 0 1 1 1 1 ORMDL family LRR_4 PF12799.7 CDS29329.1 - 2.2e-07 31.1 18.8 0.0067 16.8 0.6 5.5 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDS29329.1 - 0.019 15.0 0.2 0.61 10.3 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_9 PF14580.6 CDS29329.1 - 0.031 13.8 1.8 2.1 7.8 0.1 3.5 2 1 3 5 5 5 0 Leucine-rich repeat LRR_8 PF13855.6 CDS29329.1 - 0.095 12.5 13.2 1.3 8.9 0.7 4.5 4 2 0 4 4 4 0 Leucine rich repeat EMP24_GP25L PF01105.24 CDS29330.1 - 3.4e-41 141.2 0.0 4e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gemini_mov PF01708.16 CDS29330.1 - 0.082 12.7 0.0 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein Pkinase PF00069.25 CDS29331.1 - 2.2e-19 69.9 0.4 8.2e-19 68.0 0.4 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29331.1 - 2.2e-13 50.1 0.0 5.1e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_A31 PF05771.11 CDS29331.1 - 0.022 14.7 2.2 0.21 11.6 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A31 protein COG7 PF10191.9 CDS29332.2 - 8.2e-52 176.5 11.1 6.6e-38 130.5 14.2 2.7 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) zf-C2H2_2 PF12756.7 CDS29332.2 - 0.00061 20.1 4.7 0.02 15.2 0.3 3.1 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Cnn_1N PF07989.11 CDS29332.2 - 0.13 12.5 4.1 0.068 13.3 0.7 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Med9 PF07544.13 CDS29332.2 - 0.13 12.3 2.0 0.28 11.3 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UPAR_LY6_2 PF16975.5 CDS29332.2 - 2 8.7 6.1 5.4 7.3 0.8 2.8 3 0 0 3 3 3 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Forkhead PF00250.18 CDS29334.1 - 4.8e-34 116.5 0.0 1.5e-33 114.9 0.0 1.9 1 0 0 1 1 1 1 Forkhead domain SET PF00856.28 CDS29335.2 - 2.1e-07 31.5 0.1 3.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 SET domain zinc-ribbons_6 PF07191.12 CDS29335.2 - 0.18 11.8 5.2 0.4 10.7 5.2 1.6 1 0 0 1 1 1 0 zinc-ribbons PAS_3 PF08447.12 CDS29336.2 - 2e-11 44.0 0.0 3.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 CDS29336.2 - 2e-09 37.5 0.0 4.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 CDS29336.2 - 0.0028 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 CDS29336.2 - 0.1 12.6 0.5 0.29 11.1 0.5 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain WD40 PF00400.32 CDS29337.1 - 1e-28 99.0 21.1 1.6e-05 25.6 0.1 9.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS29337.1 - 1.8e-09 37.8 0.0 0.056 13.7 0.0 5.1 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDS29337.1 - 4.5e-09 36.6 0.1 9.3e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 CDS29337.1 - 0.00054 19.4 0.0 0.012 14.9 0.0 2.6 2 0 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 CDS29337.1 - 0.0013 17.6 0.1 0.15 10.8 0.0 2.5 2 0 0 2 2 2 2 Nup133 N terminal like PBP1_TM PF14812.6 CDS29337.1 - 0.24 11.8 6.8 0.064 13.6 3.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAS_3 PF08447.12 CDS29340.1 - 9.7e-14 51.4 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 CDS29340.1 - 5.7e-11 42.5 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 CDS29340.1 - 0.00031 20.7 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CDS29340.1 - 0.046 14.0 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 PAS fold HLH PF00010.26 CDS29340.1 - 0.1 12.6 0.5 0.3 11.1 0.5 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 CDS29340.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain SET PF00856.28 CDS29341.1 - 2.5e-07 31.2 0.0 4.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 CDS29341.1 - 0.14 12.4 0.1 0.45 10.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zinc-ribbons_6 PF07191.12 CDS29341.1 - 0.33 11.0 5.3 0.73 9.9 5.3 1.5 1 0 0 1 1 1 0 zinc-ribbons Forkhead PF00250.18 CDS29342.2 - 9.1e-29 99.6 0.0 3.1e-28 97.9 0.0 1.9 1 0 0 1 1 1 1 Forkhead domain PK PF00224.21 CDS29347.1 - 2.9e-81 273.1 0.0 4.7e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDS29347.1 - 3.1e-22 79.0 2.4 6.1e-22 78.1 1.5 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain tRNA_anti-codon PF01336.25 CDS29347.1 - 0.012 15.5 0.0 0.12 12.3 0.0 2.5 2 1 1 3 3 3 0 OB-fold nucleic acid binding domain Ribosomal_L36e PF01158.18 CDS29348.1 - 1e-33 115.4 5.4 1.2e-33 115.2 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Indigoidine_A PF04227.12 CDS29349.1 - 4.2e-111 371.0 4.9 5.8e-111 370.5 4.9 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CDS29349.1 - 7.4e-21 74.7 0.0 1.7e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DDE_3 PF13358.6 CDS29349.1 - 0.064 13.0 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease Glycos_transf_2 PF00535.26 CDS29350.1 - 6.2e-34 117.2 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDS29350.1 - 3.5e-21 75.8 1.4 2.1e-20 73.2 0.9 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDS29350.1 - 3.6e-05 23.3 0.0 7.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 CDS29350.1 - 0.00081 20.1 0.0 0.22 12.3 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_3 PF13641.6 CDS29350.1 - 0.0019 18.1 0.1 0.38 10.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDS29350.1 - 0.0058 16.1 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Lactamase_B_6 PF16661.5 CDS29353.2 - 2.2e-52 177.3 0.0 3.6e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CDS29353.2 - 4e-29 102.0 0.2 2.1e-22 80.1 0.0 3.0 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CDS29353.2 - 4.2e-06 27.0 0.1 0.00022 21.5 0.0 3.0 2 1 1 3 3 3 1 Beta-Casp domain RMMBL PF07521.12 CDS29353.2 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain SIKE PF05769.11 CDS29354.1 - 3.1e-50 170.6 16.7 3.7e-50 170.4 16.7 1.1 1 0 0 1 1 1 1 SIKE family Herpes_BLRF2 PF05812.12 CDS29354.1 - 0.0013 18.9 1.7 0.68 10.1 0.0 2.7 2 0 0 2 2 2 2 Herpesvirus BLRF2 protein EC042_2821 PF18740.1 CDS29354.1 - 0.053 13.4 2.5 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 EC042_2821-lke REase PyrI PF01948.18 CDS29354.1 - 0.06 13.6 0.4 0.86 9.9 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Spc7 PF08317.11 CDS29354.1 - 0.078 11.8 15.3 0.23 10.3 9.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 CDS29354.1 - 0.14 12.2 15.8 1.8 8.6 1.9 3.9 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-Q PF13094.6 CDS29354.1 - 0.14 12.3 18.7 3.2 7.9 14.0 2.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2508 PF10704.9 CDS29354.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF2570 PF10828.8 CDS29354.1 - 1.8 8.4 7.8 1.1 9.1 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Prefoldin_2 PF01920.20 CDS29354.1 - 2.3 8.2 16.8 0.2 11.6 4.2 3.3 3 2 0 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 CDS29354.1 - 6 7.1 20.8 0.4 10.9 7.6 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 ANAPC3 PF12895.7 CDS29355.1 - 0.001 19.2 2.8 0.021 15.1 0.2 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 KBP_C PF12309.8 CDS29355.1 - 0.079 12.5 0.5 0.17 11.4 0.2 1.7 2 0 0 2 2 2 0 KIF-1 binding protein C terminal DUF1940 PF09155.10 CDS29356.1 - 0.045 13.9 4.2 0.076 13.1 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) SbcD_C PF12320.8 CDS29356.1 - 6.3 7.2 9.2 3.4 8.0 0.8 3.1 2 2 1 3 3 3 0 Type 5 capsule protein repressor C-terminal domain SCA7 PF08313.12 CDS29358.2 - 3e-12 46.3 0.2 6.3e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain Asp_protease_2 PF13650.6 CDS29358.2 - 0.043 14.4 1.5 22 5.8 0.1 3.3 2 0 0 2 2 2 0 Aspartyl protease Tipalpha PF16753.5 CDS29358.2 - 0.15 11.9 0.2 26 4.6 0.0 2.4 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter DUF243 PF03103.17 CDS29358.2 - 4.2 7.7 13.1 5.7 7.3 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF243) SWIB PF02201.18 CDS29359.1 - 1.2e-22 79.6 0.0 2.5e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CDS29359.1 - 3.4e-18 65.3 1.3 7.5e-18 64.2 1.3 1.6 1 0 0 1 1 1 1 DEK C terminal domain TSP9 PF11493.8 CDS29359.1 - 0.46 11.2 2.9 0.77 10.5 2.3 1.7 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 PPR_2 PF13041.6 CDS29360.1 - 0.012 15.8 0.0 17 5.7 0.0 4.3 5 0 0 5 5 5 0 PPR repeat family PPR_3 PF13812.6 CDS29360.1 - 0.11 12.6 0.0 23 5.2 0.0 2.9 2 1 1 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.20 CDS29360.1 - 0.27 11.6 0.9 7 7.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat MRG PF05712.13 CDS29361.2 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 MRG DUF4596 PF15363.6 CDS29361.2 - 0.17 12.2 7.5 0.14 12.4 2.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4596) Rad51 PF08423.11 CDS29362.1 - 5.7e-131 435.4 0.0 6.6e-131 435.2 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CDS29362.1 - 2.3e-11 43.6 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CDS29362.1 - 1.9e-09 37.4 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CDS29362.1 - 7.5e-06 25.4 1.1 3.1e-05 23.4 1.1 1.9 1 1 0 1 1 1 1 KaiC AAA_28 PF13521.6 CDS29362.1 - 0.025 14.8 0.6 0.048 13.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CDS29362.1 - 0.033 13.5 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CDS29362.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS29362.1 - 0.078 13.3 0.1 0.21 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 CDS29362.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Beach PF02138.18 CDS29363.2 - 2e-125 417.7 0.0 3.5e-125 416.9 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 CDS29363.2 - 1.5e-74 250.8 0.0 3e-74 249.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) DUF1088 PF06469.11 CDS29363.2 - 1.6e-21 76.7 3.3 9.6e-11 41.6 0.0 2.8 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1088) PH_BEACH PF14844.6 CDS29363.2 - 7e-15 54.9 0.0 2.1e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CDS29363.2 - 2e-06 28.4 6.7 0.00061 20.6 0.9 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Laminin_G_3 PF13385.6 CDS29363.2 - 2.4e-06 27.8 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ANAPC4_WD40 PF12894.7 CDS29363.2 - 0.0041 17.4 0.0 4.5 7.6 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PARP PF00644.20 CDS29366.1 - 1.8e-20 73.4 0.0 5e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDS29366.1 - 1.3e-06 28.6 0.1 2.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain CRA PF06589.11 CDS29366.1 - 0.088 12.9 0.6 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) PARP PF00644.20 CDS29370.2 - 1.8e-13 50.5 0.0 2.4e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CDS29370.2 - 1e-05 25.7 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PH_BEACH PF14844.6 CDS29371.1 - 5.6e-14 52.1 0.4 1.1e-13 51.2 0.1 1.6 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Beach PF02138.18 CDS29372.1 - 5.3e-27 94.9 0.0 5.5e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Exo_endo_phos_2 PF14529.6 CDS29376.1 - 1.3e-13 50.8 0.3 2.2e-13 50.1 0.3 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS29376.1 - 6.2e-05 22.6 0.0 7.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tetraspanin PF00335.20 CDS29379.1 - 1.5e-08 34.7 8.0 1.5e-08 34.7 8.0 2.2 1 1 1 2 2 2 1 Tetraspanin family Cyclin_N PF00134.23 CDS29380.1 - 3.1e-16 59.3 0.0 2.7e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS29380.1 - 0.00021 21.3 0.1 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 CDS29380.1 - 0.0059 16.6 0.1 2.9 8.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 CDS29380.1 - 0.0099 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin C-terminal domain RVT_1 PF00078.27 CDS29381.1 - 2.5e-05 23.9 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mhr1 PF12829.7 CDS29381.1 - 0.00057 19.9 0.1 0.58 10.3 0.0 2.5 2 0 0 2 2 2 2 Transcriptional regulation of mitochondrial recombination TFIIS_C PF01096.18 CDS29382.1 - 3.7e-12 45.9 2.1 3.7e-12 45.9 2.1 3.2 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CDS29382.1 - 7.4e-12 44.9 5.0 7.4e-12 44.9 5.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.6 CDS29382.1 - 3.1e-06 27.6 5.9 4.5e-05 23.9 0.5 2.1 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Ogr_Delta PF04606.12 CDS29382.1 - 0.0055 16.7 1.9 0.0055 16.7 1.9 2.6 3 0 0 3 3 3 1 Ogr/Delta-like zinc finger CpXC PF14353.6 CDS29382.1 - 0.052 13.6 7.1 1.6 8.8 0.5 2.4 1 1 0 2 2 2 0 CpXC protein DZR PF12773.7 CDS29382.1 - 0.056 13.5 1.0 0.056 13.5 1.0 2.3 2 1 0 2 2 2 0 Double zinc ribbon DUF3268 PF11672.8 CDS29382.1 - 0.15 12.4 6.6 2.2 8.7 1.2 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain DUF3716 PF12511.8 CDS29382.1 - 0.21 11.7 8.8 0.5 10.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) C1_1 PF00130.22 CDS29382.1 - 0.24 11.3 4.4 0.53 10.2 1.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RPA_interact_C PF14768.6 CDS29382.1 - 0.37 11.4 7.2 3.6 8.2 1.7 2.6 2 1 0 2 2 2 0 Replication protein A interacting C-terminal zf-ACC PF17848.1 CDS29382.1 - 1.6 8.9 12.6 4.4 7.5 3.4 4.0 3 1 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain FYVE PF01363.21 CDS29382.1 - 2.3 8.4 8.5 0.77 9.9 0.6 2.4 2 1 0 2 2 2 0 FYVE zinc finger C1_2 PF03107.16 CDS29382.1 - 2.7 8.4 15.9 11 6.4 3.2 3.4 2 2 1 3 3 3 0 C1 domain Rho_Binding PF08912.11 CDS29384.1 - 0.043 14.6 0.7 0.052 14.4 0.7 1.1 1 0 0 1 1 1 0 Rho Binding DUF2967 PF11179.8 CDS29385.1 - 0.026 12.6 1.5 0.032 12.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MRC1 PF09444.10 CDS29385.1 - 0.3 11.6 1.9 0.39 11.2 1.9 1.1 1 0 0 1 1 1 0 MRC1-like domain Abhydrolase_2 PF02230.16 CDS29386.2 - 0.0011 18.8 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF4215 PF13948.6 CDS29388.1 - 0.0082 16.6 1.5 0.0082 16.6 1.5 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4215) DUF4704 PF15787.5 CDS29389.2 - 7e-07 28.8 0.0 9.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Tenui_PVC2 PF06656.11 CDS29389.2 - 0.4 8.5 1.2 0.48 8.3 0.3 1.4 2 0 0 2 2 2 0 Tenuivirus PVC2 protein zf-H2C2_2 PF13465.6 CDS29390.1 - 2.4e-14 53.0 13.3 8.5e-06 26.0 0.9 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS29390.1 - 1.9e-09 37.5 26.6 2.3e-05 24.6 2.8 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29390.1 - 5.3e-08 33.1 27.9 0.0027 18.4 2.2 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDS29390.1 - 0.015 15.6 11.6 1.6 9.1 0.8 3.5 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.12 CDS29390.1 - 0.1 12.9 4.1 0.13 12.5 0.3 2.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Actin_micro PF17003.5 CDS29390.1 - 0.23 10.6 4.2 0.67 9.1 0.0 2.6 2 1 0 2 2 2 0 Putative actin-like family HypA PF01155.19 CDS29390.1 - 0.59 10.2 3.9 2.4 8.2 1.0 2.8 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 CDS29390.1 - 0.71 10.7 7.0 0.4 11.5 1.9 2.8 2 1 0 2 2 2 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 CDS29390.1 - 0.98 9.0 5.5 5 6.7 0.0 3.9 4 0 0 4 4 4 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CDS29390.1 - 1.9 8.7 9.5 1.2 9.3 2.7 3.1 3 0 0 3 3 3 0 Zinc ribbon domain zf-trcl PF13451.6 CDS29390.1 - 3.5 7.6 8.0 33 4.5 4.5 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain C1_2 PF03107.16 CDS29390.1 - 3.8 7.9 15.0 10 6.5 0.6 3.9 3 1 0 3 3 3 0 C1 domain Desulfoferrod_N PF06397.12 CDS29390.1 - 5 6.8 6.7 13 5.5 0.1 2.9 3 0 0 3 3 2 0 Desulfoferrodoxin, N-terminal domain zf-C2HE PF16278.5 CDS29390.1 - 6.5 7.3 13.5 11 6.6 0.7 3.8 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger ZZ PF00569.17 CDS29390.1 - 6.7 6.6 10.9 3.1 7.7 0.1 3.6 4 0 0 4 4 4 0 Zinc finger, ZZ type DZR PF12773.7 CDS29390.1 - 7.8 6.6 9.3 22 5.2 6.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon DUF4506 PF14958.6 CDS29391.1 - 0.082 12.4 0.0 0.099 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) MICSWaP PF17018.5 CDS29393.2 - 0.004 16.7 1.9 0.0086 15.7 1.9 1.5 1 0 0 1 1 1 1 Spore wall protein KH_1 PF00013.29 CDS29395.1 - 1.6e-68 226.4 29.8 5.2e-12 45.4 0.6 13.2 15 0 0 15 15 15 10 KH domain SLS PF14611.6 CDS29395.1 - 1.4e-10 41.4 12.1 0.13 12.0 0.3 7.9 6 3 3 9 9 9 4 Mitochondrial inner-membrane-bound regulator baeRF_family5 PF18846.1 CDS29395.1 - 0.021 15.0 0.9 5.3 7.2 0.0 4.0 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 DUF3829 PF12889.7 CDS29395.1 - 0.078 12.5 2.6 0.17 11.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Ribosomal_L6 PF00347.23 CDS29395.1 - 0.3 11.8 2.1 25 5.6 0.2 4.3 4 0 0 4 4 4 0 Ribosomal protein L6 Syntaxin-6_N PF09177.11 CDS29395.1 - 1.9 9.1 8.3 2.9 8.5 0.0 4.8 6 0 0 6 6 6 0 Syntaxin 6, N-terminal Ribosomal_S8e PF01201.22 CDS29396.1 - 8e-46 155.6 0.9 8e-46 155.6 0.9 2.0 1 1 1 2 2 2 1 Ribosomal protein S8e Acid_phosphat_B PF03767.14 CDS29396.1 - 0.084 12.4 2.7 0.12 12.0 2.7 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ank_4 PF13637.6 CDS29397.1 - 2e-17 63.3 0.1 6.9e-10 39.3 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS29397.1 - 5.2e-17 62.2 0.1 1e-13 51.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS29397.1 - 8.8e-13 48.2 0.3 2.7e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29397.1 - 2.8e-12 45.7 0.1 0.0012 19.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CDS29397.1 - 6e-12 45.5 0.4 0.00033 21.0 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat RhoGAP PF00620.27 CDS29398.1 - 3.3e-23 82.2 0.4 2.6e-21 76.0 0.4 2.6 1 1 0 1 1 1 1 RhoGAP domain HJURP_mid PF12346.8 CDS29398.1 - 0.021 15.2 0.3 0.021 15.2 0.3 2.4 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat RhoGAP PF00620.27 CDS29399.1 - 5.3e-21 75.0 0.1 1.9e-19 70.0 0.0 2.7 2 1 0 2 2 2 1 RhoGAP domain NCD2 PF04905.13 CDS29399.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) LSDAT_euk PF18139.1 CDS29402.2 - 2.6e-26 92.6 0.0 4.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 SLOG in TRPM Ank_2 PF12796.7 CDS29402.2 - 7.9e-06 26.4 0.9 0.003 18.1 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) LSDAT_prok PF18171.1 CDS29402.2 - 0.00062 19.1 0.0 0.0045 16.2 0.0 2.1 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ank_3 PF13606.6 CDS29402.2 - 0.019 15.5 0.1 6.5 7.7 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat DAGAT PF03982.13 CDS29404.1 - 4.8e-83 278.5 0.2 5.1e-69 232.4 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase ALS2CR11 PF15729.5 CDS29404.1 - 0.0021 17.3 0.1 0.003 16.8 0.1 1.1 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 candidate 11 TT_ORF2 PF02957.15 CDS29407.1 - 0.067 14.1 0.1 0.11 13.5 0.1 1.3 1 0 0 1 1 1 0 TT viral ORF2 DSPc PF00782.20 CDS29408.1 - 8.7e-27 93.5 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS29408.1 - 0.00026 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Iso_dh PF00180.20 CDS29409.1 - 1.4e-103 346.7 0.0 1.7e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GAS PF13851.6 CDS29410.1 - 3.1e-41 140.9 29.0 3.1e-41 140.9 29.0 3.4 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 CDS29410.1 - 0.051 14.2 1.1 0.051 14.2 1.1 5.8 3 1 2 5 5 5 0 Initiation control protein YabA DUF3993 PF13158.6 CDS29410.1 - 5.7 7.2 6.3 2.7 8.2 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3993) HMG_box PF00505.19 CDS29411.1 - 3.1e-14 53.1 0.0 5.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MFS_1 PF07690.16 CDS29414.1 - 6.8e-38 130.5 50.0 5.1e-26 91.4 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS29414.1 - 5.4e-06 25.5 23.8 7.8e-06 25.0 23.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CDS29414.1 - 1.1e-05 24.6 5.9 1.1e-05 24.6 5.9 2.6 2 2 0 2 2 2 1 MFS_1 like family DUF2678 PF10856.8 CDS29414.1 - 1.8 8.5 7.9 2.5 8.1 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2678) TMEMspv1-c74-12 PF11044.8 CDS29414.1 - 3 7.9 6.1 13 5.9 1.9 3.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cadherin PF00028.17 CDS29415.2 - 1.5e-66 220.9 8.6 4.1e-09 36.7 0.0 13.7 13 1 0 13 13 13 10 Cadherin domain Laminin_G_2 PF02210.24 CDS29415.2 - 2e-20 73.6 0.0 2e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CDS29415.2 - 7.7e-17 61.7 0.0 2.8e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.27 CDS29415.2 - 4.4e-06 26.9 20.7 1.9e-05 24.9 6.4 5.2 5 0 0 5 5 5 2 EGF-like domain Cadherin_C PF01049.17 CDS29415.2 - 0.00023 21.5 0.1 0.00048 20.5 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_3 PF16184.5 CDS29415.2 - 0.095 12.7 16.1 2.2 8.3 0.0 7.5 9 0 0 9 9 9 0 Cadherin-like hEGF PF12661.7 CDS29415.2 - 0.15 12.7 45.2 0.057 14.1 5.2 5.9 5 0 0 5 5 5 0 Human growth factor-like EGF Adeno_E3_CR2 PF02439.15 CDS29415.2 - 0.47 10.3 3.5 1 9.2 3.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EGF_MSP1_1 PF12946.7 CDS29415.2 - 4.2 7.5 20.3 1.1 9.4 6.2 3.3 2 1 0 2 2 2 0 MSP1 EGF domain 1 SAP18 PF06487.12 CDS29416.1 - 2.4e-30 105.6 0.0 3.7e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Ribosomal_L21p PF00829.21 CDS29417.2 - 6.5e-12 45.6 0.0 1.7e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Forkhead PF00250.18 CDS29418.2 - 3.3e-33 113.8 0.0 1.2e-32 112.0 0.0 2.0 1 0 0 1 1 1 1 Forkhead domain 7tm_1 PF00001.21 CDS29419.1 - 1e-35 123.4 10.8 1.2e-35 123.1 10.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS29419.1 - 4.1e-06 26.6 19.6 6e-06 26.1 19.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDS29419.1 - 0.00022 21.1 9.4 0.00027 20.8 9.4 1.2 1 0 0 1 1 1 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.9 CDS29419.1 - 0.00024 20.6 15.6 0.00032 20.2 15.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Papilloma_E5 PF03025.14 CDS29419.1 - 0.84 9.8 13.7 0.31 11.2 1.9 2.7 2 0 0 2 2 2 0 Papillomavirus E5 GalKase_gal_bdg PF10509.9 CDS29420.1 - 3.4e-17 61.7 0.0 1.1e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CDS29420.1 - 4.2e-14 52.7 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CDS29420.1 - 8.9e-12 45.1 1.8 1.7e-11 44.2 1.8 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain ECSCR PF15820.5 CDS29421.1 - 0.0012 18.6 1.9 0.078 12.8 0.2 2.4 2 0 0 2 2 2 2 Endothelial cell-specific chemotaxis regulator TMEM52 PF14979.6 CDS29421.1 - 0.098 12.6 1.9 0.18 11.7 0.5 2.1 3 0 0 3 3 3 0 Transmembrane 52 Ribosomal_L37ae PF01780.19 CDS29421.1 - 0.34 11.0 2.5 0.35 11.0 0.9 1.8 2 0 0 2 2 2 0 Ribosomal L37ae protein family Rho_GDI PF02115.17 CDS29423.1 - 2.1e-47 161.4 0.2 2.4e-47 161.2 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor HEAT PF02985.22 CDS29424.1 - 4.1e-28 95.0 31.7 0.00049 20.1 0.0 12.7 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 CDS29424.1 - 1.7e-21 76.4 22.4 5.8e-06 26.6 0.0 7.6 3 3 5 9 9 9 8 HEAT repeats Adaptin_N PF01602.20 CDS29424.1 - 1.9e-07 30.0 2.1 4.1e-06 25.6 0.2 2.9 3 1 0 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.6 CDS29424.1 - 2.2e-07 31.3 17.8 0.0048 17.4 0.0 7.9 6 2 3 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDS29424.1 - 5.4e-07 30.1 0.0 0.0022 18.5 0.0 4.8 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDS29424.1 - 0.00078 19.5 5.1 8.2 6.5 0.1 5.1 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDS29424.1 - 0.0073 15.9 0.1 0.33 10.5 0.1 3.4 3 1 0 3 3 3 1 CLASP N terminal Arm PF00514.23 CDS29424.1 - 0.019 15.0 2.2 0.46 10.6 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IPK PF03770.16 CDS29425.1 - 3.7e-32 111.8 0.0 5.4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase 7tm_1 PF00001.21 CDS29426.1 - 2.9e-05 23.5 0.6 2.9e-05 23.5 0.6 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DHHC PF01529.20 CDS29426.1 - 4.6 7.4 13.2 2.1 8.4 0.4 3.3 3 1 0 3 3 3 0 DHHC palmitoyltransferase TSNAXIP1_N PF15739.5 CDS29427.1 - 4.8e-24 84.9 0.2 4.8e-24 84.9 0.2 3.6 3 1 1 4 4 3 1 Translin-associated factor X-interacting N-terminus DUF16 PF01519.16 CDS29427.1 - 4.7e-05 23.8 11.6 0.00016 22.1 7.2 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF16 MbeD_MobD PF04899.12 CDS29427.1 - 0.00018 21.5 0.4 0.0067 16.5 0.0 2.9 2 1 0 2 2 2 1 MbeD/MobD like ATG16 PF08614.11 CDS29427.1 - 0.00096 19.4 12.4 0.019 15.2 5.1 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.9 CDS29427.1 - 0.0021 18.0 6.9 0.0021 18.0 6.9 3.3 1 1 2 3 3 3 1 Axonemal dynein light chain DUF4407 PF14362.6 CDS29427.1 - 0.032 13.6 7.1 0.1 11.9 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CDS29427.1 - 0.073 13.5 18.5 0.52 10.7 10.8 2.3 1 1 1 2 2 2 0 Fez1 Tup_N PF08581.10 CDS29427.1 - 0.081 13.2 19.2 3.9 7.8 2.5 4.3 3 1 1 4 4 4 0 Tup N-terminal Rho_Binding PF08912.11 CDS29427.1 - 0.2 12.5 18.1 2.8 8.8 5.1 4.1 3 1 1 4 4 3 0 Rho Binding Tho2 PF11262.8 CDS29427.1 - 0.31 10.2 14.4 0.032 13.4 6.9 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4413 PF14372.6 CDS29427.1 - 0.35 11.3 3.5 2.3 8.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) ADIP PF11559.8 CDS29427.1 - 0.39 10.8 11.3 0.68 10.0 5.3 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CDS29427.1 - 0.61 8.9 21.9 1.8 7.4 15.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 CDS29427.1 - 1.3 9.5 22.2 0.92 10.0 12.0 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Bap31_Bap29_C PF18035.1 CDS29427.1 - 1.6 8.8 16.8 5.1 7.2 6.3 4.1 3 1 1 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cnn_1N PF07989.11 CDS29427.1 - 1.8 8.8 16.2 5.7 7.2 1.8 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 CDS29427.1 - 2 8.3 15.6 0.48 10.2 0.3 3.5 4 0 0 4 4 3 0 Septum formation initiator DUF745 PF05335.13 CDS29427.1 - 2 8.1 7.9 4 7.1 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Lectin_N PF03954.14 CDS29427.1 - 2.2 8.1 6.1 0.92 9.3 2.2 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Sod_Ni PF09055.11 CDS29427.1 - 2.4 8.7 6.9 2.7 8.6 0.3 2.9 2 1 1 3 3 3 0 Nickel-containing superoxide dismutase TPR_MLP1_2 PF07926.12 CDS29427.1 - 2.4 8.2 20.1 1 9.5 7.3 3.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3496 PF12001.8 CDS29427.1 - 2.6 8.5 15.0 0.074 13.4 5.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3496) SlyX PF04102.12 CDS29427.1 - 3.3 8.4 10.4 4.7 7.9 0.3 3.8 2 1 1 3 3 3 0 SlyX Atg14 PF10186.9 CDS29427.1 - 3.4 6.7 12.4 25 3.8 12.1 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 CDS29427.1 - 3.6 7.8 21.4 0.92 9.8 11.0 3.1 3 2 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 CDS29427.1 - 4.8 7.7 8.9 2 8.9 0.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD_2 PF14197.6 CDS29427.1 - 5.1 7.2 15.3 1.4 9.1 0.1 4.1 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 BRE1 PF08647.11 CDS29427.1 - 5.5 7.1 16.8 12 6.1 11.6 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4600 PF15372.6 CDS29427.1 - 7.6 7.0 17.9 0.33 11.4 8.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) End3 PF12761.7 CDS29427.1 - 7.9 6.6 16.2 10 6.2 4.5 2.3 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Laminin_II PF06009.12 CDS29427.1 - 9.5 6.2 12.7 8.7 6.4 1.0 2.8 2 2 0 2 2 2 0 Laminin Domain II CPSF_A PF03178.15 CDS29428.1 - 9.1e-62 209.2 0.1 1.6e-61 208.4 0.1 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CDS29428.1 - 6.3e-23 81.2 0.0 6e-15 54.9 0.0 2.5 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Aldo_ket_red PF00248.21 CDS29429.1 - 4e-56 190.4 0.0 6.2e-56 189.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Skp1 PF01466.19 CDS29429.1 - 0.08 13.1 1.5 0.39 10.9 0.3 2.2 2 0 0 2 2 2 0 Skp1 family, dimerisation domain FOXP-CC PF16159.5 CDS29431.1 - 0.0018 18.8 19.8 0.52 11.0 0.2 5.9 4 2 2 6 6 6 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CDS29431.1 - 0.011 15.7 3.2 3 7.9 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS29431.1 - 0.024 15.1 1.1 0.43 11.1 0.2 7.5 9 0 0 9 9 9 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS29431.1 - 0.052 14.0 13.8 0.054 13.9 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS29431.1 - 0.099 13.5 0.2 0.099 13.5 0.2 8.6 10 0 0 10 10 10 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDS29431.1 - 0.34 10.8 10.4 4.5 7.2 0.1 4.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 CDS29431.1 - 0.83 9.5 0.0 0.83 9.5 0.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Armet PF10208.9 CDS29432.1 - 4.5e-25 88.3 0.6 5e-25 88.1 0.6 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CDS29432.1 - 7.2e-05 22.4 0.1 0.00016 21.4 0.1 1.5 1 0 0 1 1 1 1 SAP domain OST3_OST6 PF04756.13 CDS29433.1 - 1.8e-44 152.3 5.1 2.1e-44 152.0 5.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Herpes_US9 PF06072.11 CDS29433.1 - 0.15 12.0 1.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Ku PF02735.16 CDS29433.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DUF624 PF04854.14 CDS29433.1 - 0.17 12.0 6.1 0.44 10.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF624 DUF4131 PF13567.6 CDS29433.1 - 0.6 9.7 6.1 4.4 6.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ASH PF15780.5 CDS29434.1 - 5.9e-47 157.9 40.4 1.8e-06 28.1 0.0 21.7 24 0 0 24 24 24 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CDS29434.1 - 5.7e-19 68.2 0.6 0.29 11.3 0.0 11.7 12 0 0 12 12 12 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CDS29434.1 - 1e-13 51.1 36.4 0.0024 17.7 1.2 14.5 14 1 1 15 15 15 5 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CDS29434.1 - 3.2e-08 33.7 22.4 0.1 12.9 0.0 12.0 15 0 0 15 15 15 2 Transmembrane protein 131-like Hydin_ADK PF17213.3 CDS29434.1 - 6.3e-05 23.3 0.4 0.00033 21.0 0.4 2.3 1 1 0 1 1 1 1 Hydin Adenylate kinase-like domain DUF1573 PF07610.11 CDS29434.1 - 0.0036 17.3 27.5 0.4 10.8 0.1 12.7 16 0 0 16 16 16 1 Protein of unknown function (DUF1573) STN PF07660.14 CDS29434.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain DnaJ PF00226.31 CDS29435.1 - 2.5e-22 78.7 0.7 4.8e-22 77.8 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Glycoamylase PF10091.9 CDS29435.1 - 0.0021 17.6 0.2 0.0028 17.3 0.2 1.2 1 0 0 1 1 1 1 Putative glucoamylase Fringe PF02434.16 CDS29436.1 - 3.6e-07 29.9 0.0 1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Fringe PF02434.16 CDS29437.1 - 1.6e-12 47.4 0.1 3.9e-11 42.9 0.1 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDS29437.1 - 1.1e-05 25.4 0.2 0.013 15.3 0.2 2.2 1 1 1 2 2 2 2 Galactosyltransferase OST3_OST6 PF04756.13 CDS29438.1 - 3.1e-89 299.2 2.1 3.7e-89 298.9 2.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Cation_ATPase_C PF00689.21 CDS29438.1 - 0.058 13.1 2.8 1.6 8.4 0.3 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Thioredoxin PF00085.20 CDS29438.1 - 0.069 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Fringe PF02434.16 CDS29439.1 - 1.1e-06 28.3 0.0 4.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CDS29439.1 - 0.0071 16.2 0.1 2 8.2 0.1 2.3 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 CDS29441.1 - 4e-21 75.6 0.0 1.1e-09 38.2 0.0 3.2 2 2 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 CDS29441.1 - 1.6e-16 60.7 0.9 0.0079 16.0 0.2 4.3 2 2 2 4 4 4 4 Galactosyltransferase Amidohydro_2 PF04909.14 CDS29442.1 - 8.6e-21 75.0 0.1 1.2e-19 71.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase XRCC4 PF06632.12 CDS29442.1 - 0.21 10.4 8.3 0.55 9.0 8.3 1.6 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CAF-1_p150 PF11600.8 CDS29442.1 - 5.3 6.7 22.7 13 5.5 22.7 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 CDS29442.1 - 8.8 6.1 7.6 1.8 8.4 3.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 tRNA_anti-codon PF01336.25 CDS29444.1 - 4.8e-06 26.5 0.1 0.00013 21.9 0.1 2.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain STN1_2 PF09170.10 CDS29444.1 - 0.0022 18.2 0.1 0.0039 17.4 0.1 1.4 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 MarR PF01047.22 CDS29444.1 - 0.011 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 MarR family Stn1 PF10451.9 CDS29444.1 - 0.085 11.8 0.2 0.75 8.7 0.2 2.2 2 0 0 2 2 2 0 Telomere regulation protein Stn1 7tm_1 PF00001.21 CDS29445.1 - 0.18 11.1 7.6 0.31 10.3 6.7 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Asparaginase PF00710.20 CDS29446.1 - 2.6e-52 177.1 0.0 4.6e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CDS29446.1 - 9.3e-26 90.3 0.0 1.8e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CDS29446.1 - 3.2e-14 53.3 0.1 2e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS29446.1 - 1.8e-10 40.8 0.7 1.3e-06 28.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS29446.1 - 5.3e-08 33.3 0.0 0.0012 19.4 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29446.1 - 6.3e-07 29.2 0.3 1 10.2 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDS29446.1 - 8.2e-05 22.9 0.4 2 9.0 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat DEAD PF00270.29 CDS29448.1 - 1e-55 188.2 0.0 1.6e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS29448.1 - 4.9e-25 88.0 0.0 9.1e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 CDS29448.1 - 1.3e-19 70.5 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain TAL_FSA PF00923.19 CDS29449.1 - 1.7e-95 319.7 0.5 1.9e-95 319.5 0.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Nucleoporin_N PF08801.11 CDS29450.1 - 3.1e-43 148.2 0.5 5.2e-43 147.4 0.5 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Keratin_2_head PF16208.5 CDS29450.1 - 0.04 14.0 5.1 0.092 12.9 5.1 1.5 1 0 0 1 1 1 0 Keratin type II head Tctex-1 PF03645.13 CDS29451.1 - 1.3e-12 47.8 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family ASC PF00858.24 CDS29452.1 - 1.2e-56 192.5 1.4 2.1e-56 191.8 1.4 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Enolase_C PF00113.22 CDS29453.1 - 1.5e-05 24.4 0.2 3.8e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain EF-hand_1 PF00036.32 CDS29454.1 - 1.5e-21 74.3 0.9 2.9e-06 26.4 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDS29454.1 - 1.5e-20 73.4 0.9 4.3e-12 46.3 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS29454.1 - 7.4e-17 59.8 1.7 0.0003 20.5 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CDS29454.1 - 5e-16 57.4 4.0 4.3e-06 26.0 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDS29454.1 - 2.7e-14 52.8 2.9 0.0015 18.4 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS29454.1 - 4.1e-06 27.1 0.1 0.62 10.4 0.0 3.2 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS29454.1 - 4.7e-06 26.5 1.2 0.27 11.2 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CDS29454.1 - 0.0054 16.6 1.6 4.4 7.2 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CDS29454.1 - 0.021 15.1 0.1 3.1 8.2 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain NADPH_Ox PF08414.10 CDS29454.1 - 0.025 14.9 0.8 0.82 10.0 0.3 2.7 2 1 1 3 3 3 0 Respiratory burst NADPH oxidase Dockerin_1 PF00404.18 CDS29454.1 - 0.041 14.1 0.3 15 5.9 0.0 2.9 2 1 1 3 3 3 0 Dockerin type I domain Caleosin PF05042.13 CDS29454.1 - 0.054 13.4 0.7 16 5.4 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein DUF5069 PF16798.5 CDS29454.1 - 0.057 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Homez PF11569.8 CDS29454.1 - 0.089 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez FAM60A PF15396.6 CDS29455.2 - 7.8e-30 104.5 13.0 2.2e-29 103.0 13.0 1.8 1 0 0 1 1 1 1 Protein Family FAM60A TerB PF05099.13 CDS29455.2 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB Miga PF10265.9 CDS29455.2 - 8.9 5.2 26.1 0.024 13.6 8.8 2.7 3 0 0 3 3 3 0 Mitoguardin Glyco_transf_92 PF01697.27 CDS29457.1 - 5.4e-22 78.7 1.3 9.5e-22 77.9 1.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CDS29457.1 - 0.026 15.0 0.1 0.068 13.7 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.26 CDS29458.1 - 2.1e-53 179.7 0.0 2.4e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDS29458.1 - 0.0016 18.7 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CDS29458.1 - 0.0084 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDS29458.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain SRX PF09201.10 CDS29459.1 - 0.022 14.6 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit SPRY PF00622.28 CDS29460.1 - 9.6e-17 61.2 0.7 3.8e-08 33.5 0.0 3.2 4 0 0 4 4 4 2 SPRY domain FERM_M PF00373.18 CDS29460.1 - 3.4e-11 43.6 0.0 1.2e-10 41.8 0.0 2.0 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDS29460.1 - 6.2e-10 38.9 0.0 1.8e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.10 CDS29460.1 - 1.7e-09 37.9 0.0 3.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain HlyIII PF03006.20 CDS29461.1 - 4.9e-13 49.3 8.2 6.4e-13 48.9 8.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_U4 PF03419.13 CDS29461.1 - 5.3 6.2 8.9 27 3.9 8.9 1.8 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Haspin_kinase PF12330.8 CDS29462.1 - 3.8e-39 134.7 0.9 4.9e-39 134.3 0.9 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 CDS29462.1 - 0.023 14.0 0.0 0.05 13.0 0.0 1.8 1 1 0 1 1 1 0 Protein kinase domain zf-TAZ PF02135.16 CDS29463.1 - 2.9e-10 40.5 13.1 4.7e-10 39.8 13.1 1.3 1 0 0 1 1 1 1 TAZ zinc finger KIX PF02172.16 CDS29463.1 - 0.00011 22.3 0.1 0.00028 21.1 0.1 1.7 1 0 0 1 1 1 1 KIX domain Radical_SAM PF04055.21 CDS29464.1 - 8e-16 58.9 0.0 1.4e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 CDS29464.1 - 4.8e-13 49.0 0.7 9.6e-07 28.8 0.1 2.6 2 0 0 2 2 2 2 Uncharacterized protein family UPF0004 TRAM PF01938.20 CDS29464.1 - 1.3e-05 25.1 0.1 2.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Ldl_recept_a PF00057.18 CDS29464.1 - 6.8e-05 23.0 41.2 0.00047 20.3 4.3 4.7 4 0 0 4 4 4 2 Low-density lipoprotein receptor domain class A Phosducin PF02114.16 CDS29465.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Phosducin KAP PF05804.12 CDS29465.1 - 0.13 10.3 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Thioredoxin PF00085.20 CDS29466.1 - 9.1e-58 192.6 2.5 1.3e-30 105.4 0.0 3.6 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 CDS29466.1 - 5.6e-34 117.7 12.4 5.6e-28 98.1 3.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDS29466.1 - 8e-12 45.6 2.5 7e-05 23.2 0.0 3.8 4 2 1 5 5 5 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDS29466.1 - 3.3e-08 33.6 0.7 0.025 14.7 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDS29466.1 - 7.4e-08 32.6 0.8 0.0042 17.4 0.0 4.6 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 CDS29466.1 - 5.2e-07 29.3 0.1 0.013 14.9 0.0 2.5 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 CDS29466.1 - 1.1e-06 27.9 6.8 1.8e-06 27.2 6.8 1.4 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.13 CDS29466.1 - 1.1e-05 25.6 1.2 1.7 8.8 0.0 4.7 4 1 1 5 5 5 2 ERp29, N-terminal domain AhpC-TSA PF00578.21 CDS29466.1 - 0.00015 21.7 0.1 0.46 10.4 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family TraF PF13728.6 CDS29466.1 - 0.00069 19.5 0.1 0.022 14.6 0.0 2.8 3 1 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDS29466.1 - 0.0028 17.9 1.6 0.076 13.2 0.0 3.5 3 1 0 3 3 3 1 Glutaredoxin Redoxin PF08534.10 CDS29466.1 - 0.079 12.7 0.1 9.9 5.9 0.0 2.7 2 0 0 2 2 2 0 Redoxin Ribosomal_L16 PF00252.18 CDS29467.1 - 4.8e-43 146.3 0.1 5.8e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DAD PF02109.16 CDS29468.1 - 1.2e-41 141.5 4.9 1.4e-41 141.2 4.9 1.1 1 0 0 1 1 1 1 DAD family CybS PF05328.12 CDS29468.1 - 0.025 14.3 0.1 0.041 13.6 0.1 1.4 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit 5_nucleotid PF05761.14 CDS29469.1 - 4.9e-159 530.1 2.8 6e-159 529.8 2.8 1.1 1 0 0 1 1 1 1 5' nucleotidase family Talin_middle PF09141.10 CDS29470.1 - 2.3e-58 196.8 2.3 2.3e-58 196.8 2.3 11.0 11 3 1 12 12 12 2 Talin, middle domain I_LWEQ PF01608.17 CDS29470.1 - 4.4e-35 121.2 3.2 4.4e-35 121.2 3.2 12.7 10 4 2 12 12 12 4 I/LWEQ domain FERM_M PF00373.18 CDS29470.1 - 8.5e-27 93.9 0.0 4.1e-26 91.7 0.0 2.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDS29470.1 - 6.4e-14 51.7 0.1 1.3e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain IRS PF02174.17 CDS29470.1 - 4.6e-07 29.6 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) baeRF_family8 PF18851.1 CDS29470.1 - 0.0066 16.5 0.5 8.4 6.5 0.0 4.0 3 0 0 3 3 3 1 Bacterial archaeo-eukaryotic release factor family 8 ACBP PF00887.19 CDS29470.1 - 0.0079 16.4 0.0 0.036 14.3 0.0 2.2 1 0 0 1 1 1 1 Acyl CoA binding protein ubiquitin PF00240.23 CDS29470.1 - 0.15 11.8 0.0 0.54 10.0 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin family Orthopox_F7 PF05813.12 CDS29470.1 - 0.21 11.7 0.3 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus F7 protein Rad60-SLD PF11976.8 CDS29470.1 - 0.23 11.3 0.5 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like 5_nucleotid PF05761.14 CDS29471.1 - 1.3e-164 548.5 2.2 1.5e-164 548.3 2.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family DUF2288 PF10052.9 CDS29471.1 - 0.03 14.4 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Vps36-NZF-N PF16988.5 CDS29472.1 - 4.7 6.7 6.7 2.3 7.7 0.1 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TUDOR PF00567.24 CDS29473.1 - 1.2e-08 35.0 0.2 3.9e-08 33.3 0.1 1.9 2 0 0 2 2 2 1 Tudor domain KH_1 PF00013.29 CDS29473.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 KH domain Na_Ca_ex PF01699.24 CDS29474.1 - 5.7e-54 182.2 39.6 1.4e-29 103.0 20.3 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SAM_4 PF18017.1 CDS29475.1 - 6.5e-19 67.7 0.2 1e-18 67.1 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF5577 PF17740.1 CDS29475.1 - 2.5e-13 50.4 7.6 4.2e-08 33.2 0.4 2.9 2 1 0 2 2 2 2 Family of unknown function (DUF5577) SAM_2 PF07647.17 CDS29475.1 - 7.6e-07 29.2 0.1 1.4e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS29475.1 - 2.6e-05 24.5 0.3 4.8e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Tom37 PF10568.9 CDS29476.1 - 4.6e-24 85.1 0.1 9.6e-24 84.1 0.1 1.5 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CDS29476.1 - 1e-17 63.7 1.2 1.4e-16 60.0 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDS29476.1 - 2.6e-10 40.9 0.0 4.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDS29476.1 - 0.0012 18.8 0.1 0.0038 17.2 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS29476.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain O-antigen_lig PF13425.6 CDS29478.1 - 0.22 10.2 1.2 0.23 10.2 1.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4718 PF15842.5 CDS29478.1 - 0.62 9.8 11.3 0.093 12.5 6.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) Presenilin PF01080.17 CDS29478.1 - 1.2 7.8 4.5 1.4 7.6 4.5 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 CDS29480.1 - 1.4e-22 78.8 47.5 0.00013 22.2 0.8 7.6 7 1 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS29480.1 - 1.2e-19 69.8 42.2 2.2e-06 27.8 2.3 9.4 9 1 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS29480.1 - 1.5e-19 69.0 42.7 0.0018 18.9 1.6 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS29480.1 - 7.9e-11 41.9 24.4 0.0008 19.6 0.6 7.3 7 1 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS29480.1 - 4.1e-09 36.5 27.6 0.036 14.5 0.4 7.1 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDS29480.1 - 4.2e-08 33.0 40.6 0.0001 22.2 0.1 7.1 6 2 1 7 7 7 3 C2H2-type zinc finger zf-BED PF02892.15 CDS29480.1 - 1.3e-05 25.1 25.7 0.16 12.0 0.3 5.6 2 1 3 5 5 5 3 BED zinc finger zf-Di19 PF05605.12 CDS29480.1 - 0.00026 21.2 25.7 0.37 11.1 1.0 4.9 2 2 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 CDS29480.1 - 0.00055 20.1 8.6 1.5 9.0 2.9 4.6 1 1 4 5 5 5 1 Domain of unknown function (DUF4451) zf-C2H2_2 PF12756.7 CDS29480.1 - 0.0013 19.0 23.9 0.51 10.7 1.6 6.3 2 2 4 6 6 6 1 C2H2 type zinc-finger (2 copies) DUF2256 PF10013.9 CDS29480.1 - 0.034 14.3 9.5 2 8.6 0.0 4.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 CDS29480.1 - 0.051 13.2 21.2 0.15 11.7 0.2 6.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger SelR PF01641.18 CDS29480.1 - 0.19 11.8 3.9 2.6 8.1 0.1 2.9 3 0 0 3 3 2 0 SelR domain zf-H2C2_5 PF13909.6 CDS29480.1 - 0.21 11.4 0.1 0.21 11.4 0.1 6.1 6 0 0 6 6 5 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CDS29480.1 - 0.54 10.9 19.3 0.63 10.7 0.6 5.0 3 2 3 6 6 6 0 Zinc finger C2H2-type, 3 repeats Actin_micro PF17003.5 CDS29480.1 - 0.77 8.9 6.6 34 3.5 0.1 3.7 2 1 0 2 2 2 0 Putative actin-like family zf-C2H2_12 PF18658.1 CDS29480.1 - 0.85 9.2 14.4 5.2 6.7 0.2 4.7 2 2 3 5 5 5 0 Zinc-finger C2H2-type SIR2 PF02146.17 CDS29480.1 - 2.6 7.9 9.1 0.43 10.5 0.4 2.6 3 0 0 3 3 2 0 Sir2 family GAGA PF09237.11 CDS29480.1 - 3.8 7.4 19.6 0.82 9.5 0.3 5.1 5 1 1 6 6 6 0 GAGA factor FYVE PF01363.21 CDS29480.1 - 4.5 7.5 25.3 24 5.2 3.3 4.0 2 2 1 3 3 3 0 FYVE zinc finger DZR PF12773.7 CDS29480.1 - 5.4 7.1 22.2 13 5.9 5.7 4.6 2 2 1 3 3 3 0 Double zinc ribbon ADK_lid PF05191.14 CDS29480.1 - 7.2 6.7 11.6 0.61 10.1 0.4 3.9 4 1 1 5 5 4 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 CDS29480.1 - 8 6.3 30.9 0.32 10.8 2.9 5.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 CDS29480.1 - 8.4 7.2 19.4 12 6.7 1.1 4.3 3 2 0 4 4 4 0 zinc-ribbon family Tropomodulin PF03250.14 CDS29481.1 - 4.5e-55 185.6 5.4 8.1e-55 184.7 5.4 1.4 1 0 0 1 1 1 1 Tropomodulin Raco_middle PF17651.1 CDS29481.1 - 0.05 13.3 0.5 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 RACo middle region Nif11 PF07862.11 CDS29481.1 - 0.079 13.3 1.7 5.6 7.3 0.1 3.2 3 0 0 3 3 3 0 Nif11 domain Nup160 PF11715.8 CDS29481.1 - 0.081 11.6 0.3 0.11 11.1 0.3 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 LRR_6 PF13516.6 CDS29481.1 - 3.1 8.1 5.1 13 6.2 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 CDS29481.1 - 8.1 7.0 11.7 3 8.4 0.6 3.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Ras PF00071.22 CDS29482.1 - 1.7e-60 203.3 1.6 2e-60 203.1 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS29482.1 - 4.5e-33 114.0 0.9 7.8e-33 113.2 0.9 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS29482.1 - 1.5e-13 50.6 0.3 1.9e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDS29482.1 - 9.2e-07 28.5 0.2 9.6e-06 25.2 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDS29482.1 - 7.6e-05 22.8 0.2 0.00021 21.4 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDS29482.1 - 0.00016 21.2 0.1 0.00025 20.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CDS29482.1 - 0.0016 18.0 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDS29482.1 - 0.0018 17.8 0.3 0.008 15.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS29482.1 - 0.0043 17.0 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase CPT PF07931.12 CDS29482.1 - 0.0072 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 CDS29482.1 - 0.06 13.1 1.0 0.26 11.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CDS29482.1 - 0.065 13.6 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Pro_isomerase PF00160.21 CDS29483.1 - 1.3e-45 155.5 0.2 1.5e-45 155.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CDC37_M PF08565.11 CDS29484.1 - 8.5e-21 74.1 0.1 2.4e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CDS29484.1 - 1.7e-12 47.4 2.3 1.7e-12 47.4 2.3 3.5 3 2 0 3 3 3 1 Cdc37 C terminal domain CDC37_N PF03234.14 CDS29484.1 - 1.6e-11 45.2 22.6 1.6e-11 45.2 22.6 3.1 2 2 0 2 2 2 1 Cdc37 N terminal kinase binding Sigma70_r4_2 PF08281.12 CDS29484.1 - 0.27 10.9 3.0 4.3 7.1 0.1 3.1 2 1 1 3 3 3 0 Sigma-70, region 4 TcpS PF17456.2 CDS29484.1 - 0.35 10.9 6.4 0.91 9.6 6.4 1.7 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S zf-C2H2_4 PF13894.6 CDS29485.1 - 8.4e-23 79.1 133.3 0.0016 19.1 1.2 17.5 18 1 1 19 19 19 10 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS29485.1 - 4e-12 45.9 126.8 0.00012 22.4 3.0 15.2 17 1 0 17 17 17 8 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CDS29485.1 - 5.6e-08 32.6 65.7 0.002 18.1 0.2 11.4 11 0 0 11 11 11 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS29485.1 - 3.2e-07 30.5 104.2 0.0015 18.9 0.8 15.5 18 0 0 18 18 18 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS29485.1 - 0.012 15.9 68.0 0.5 10.7 0.3 12.7 13 0 0 13 13 13 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS29485.1 - 0.021 14.6 0.7 0.021 14.6 0.7 8.2 9 0 0 9 9 9 0 zinc-finger C2H2-type DUF2321 PF10083.9 CDS29485.1 - 0.033 13.8 0.3 0.033 13.8 0.3 5.1 3 1 3 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2321) SPT6_acidic PF14632.6 CDS29485.1 - 0.73 10.5 9.0 2.9 8.5 9.0 2.1 1 1 0 1 1 1 0 Acidic N-terminal SPT6 DUF678 PF05077.12 CDS29485.1 - 0.78 9.9 9.3 1.7 8.8 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF678) Kelch_1 PF01344.25 CDS29486.1 - 6.3e-22 76.9 0.1 5.8e-13 48.2 0.1 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDS29486.1 - 2.8e-17 62.3 1.3 4.8e-09 36.2 0.1 4.6 2 2 2 4 4 4 2 Kelch motif BTB PF00651.31 CDS29486.1 - 2.3e-14 53.6 0.0 4.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CDS29486.1 - 1.1e-09 38.1 0.1 2e-06 27.7 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS29486.1 - 6.3e-08 32.7 0.9 0.00075 19.7 0.1 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS29486.1 - 1e-07 31.8 0.4 0.024 14.6 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDS29486.1 - 2.2e-07 30.6 0.0 0.0045 16.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif BACK PF07707.15 CDS29486.1 - 0.00037 20.5 0.1 0.0008 19.5 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch CUB PF00431.20 CDS29488.1 - 1.5e-20 73.6 0.0 2e-19 70.0 0.0 2.5 2 0 0 2 2 2 1 CUB domain Ldl_recept_a PF00057.18 CDS29488.1 - 0.0054 16.9 5.7 0.0054 16.9 5.7 2.2 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF4199 PF13858.6 CDS29488.1 - 0.048 14.1 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TFIIA PF03153.13 CDS29488.1 - 0.14 12.1 21.9 0.3 11.0 21.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Orf78 PF06024.12 CDS29488.1 - 0.67 10.3 0.0 0.67 10.3 0.0 3.4 3 0 0 3 3 3 0 Orf78 (ac78) ANAPC4_WD40 PF12894.7 CDS29489.2 - 2.1e-19 69.6 0.2 0.00013 22.2 0.3 4.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS29489.2 - 1.8e-14 53.9 3.0 0.00018 22.2 0.3 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.11 CDS29489.2 - 1.4e-05 25.1 0.1 0.013 15.4 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CDS29489.2 - 0.017 15.0 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 CDS29489.2 - 0.15 10.0 0.2 0.97 7.3 0.1 2.0 1 1 1 2 2 2 0 IKI3 family WD40_like PF17005.5 CDS29489.2 - 0.22 10.8 0.0 8.1 5.7 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain GST_N_3 PF13417.6 CDS29490.1 - 2e-18 66.6 0.0 3.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDS29490.1 - 1.4e-12 47.7 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDS29490.1 - 3.1e-11 43.5 0.0 1.1e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS29490.1 - 1.6e-09 37.6 0.0 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 CDS29490.1 - 3.7e-06 27.5 0.0 0.00018 22.0 0.0 2.8 2 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS29490.1 - 5.5e-06 26.5 0.0 1.3e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDS29490.1 - 7.7e-05 23.4 0.0 0.0002 22.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 CDS29490.1 - 7.7e-05 22.8 0.0 0.0003 20.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CDS29490.1 - 0.00023 21.3 0.1 0.00046 20.3 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin Gpi1 PF05024.15 CDS29491.1 - 2.7e-22 79.8 7.1 2.7e-22 79.8 7.1 2.8 2 1 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) OSCP PF00213.18 CDS29492.1 - 1.3e-46 158.9 0.2 1.5e-46 158.6 0.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2666 PF10869.8 CDS29492.1 - 0.048 13.9 0.4 0.44 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Ig_3 PF13927.6 CDS29493.1 - 1.2e-09 38.6 0.0 3.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS29493.1 - 1.7e-08 34.4 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CDS29493.1 - 3.7e-08 33.4 0.0 7.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDS29493.1 - 3.6e-06 27.2 0.0 8.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDS29493.1 - 0.00059 20.0 0.1 0.02 15.1 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_5 PF16681.5 CDS29493.1 - 0.014 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ADH_zinc_N_2 PF13602.6 CDS29494.1 - 4.5e-13 50.4 0.0 1.5e-12 48.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDS29494.1 - 1.6e-12 47.3 1.0 3.4e-12 46.2 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SlyX PF04102.12 CDS29494.1 - 0.07 13.8 18.8 0.14 12.7 1.3 4.6 4 0 0 4 4 4 0 SlyX PhoU PF01895.19 CDS29494.1 - 2.2 8.8 7.4 4.6 7.8 2.9 2.8 2 0 0 2 2 2 0 PhoU domain FliJ PF02050.16 CDS29494.1 - 2.9 8.1 17.3 0.16 12.2 2.2 3.2 3 0 0 3 3 3 0 Flagellar FliJ protein IFP_35_N PF07334.13 CDS29494.1 - 4.2 7.5 8.6 0.59 10.2 0.1 3.7 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4718 PF15842.5 CDS29497.1 - 0.27 11.0 5.5 0.37 10.6 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) ALIX_LYPXL_bnd PF13949.6 CDS29500.2 - 0.37 10.1 1.8 2.5 7.3 0.5 2.3 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV Thymidylate_kin PF02223.17 CDS29501.1 - 5.5e-30 104.4 0.0 1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 CDS29501.1 - 0.00032 21.0 0.0 0.00053 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS29501.1 - 0.01 16.4 0.1 0.08 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain YL1 PF05764.13 CDS29502.1 - 0.036 14.2 10.7 0.08 13.0 10.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Astro_capsid_p PF12226.8 CDS29502.1 - 0.15 11.2 5.7 0.23 10.6 5.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 CDS29502.1 - 0.22 9.8 5.8 0.32 9.2 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 CDS29502.1 - 1.1 9.6 9.1 1.7 8.9 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) KIND PF16474.5 CDS29502.1 - 5 7.0 9.0 10 6.0 9.0 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Pkinase PF00069.25 CDS29503.1 - 6.2e-45 153.6 0.5 9.4e-44 149.7 0.0 2.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29503.1 - 9.7e-17 61.1 0.0 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29503.1 - 1.2e-07 31.4 0.0 3.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 CDS29503.1 - 0.0042 16.7 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PKcGMP_CC PF16808.5 CDS29503.1 - 0.11 12.3 2.4 0.4 10.6 2.4 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec34 PF04136.15 CDS29503.1 - 0.16 11.9 11.8 0.14 12.0 5.3 3.2 2 1 1 3 3 3 0 Sec34-like family MscS_TM PF12794.7 CDS29503.1 - 4.1 6.2 6.7 4.1 6.2 4.8 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Acetyltransf_13 PF13880.6 CDS29504.1 - 1.5e-23 82.5 0.0 2.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CDS29504.1 - 7.1e-18 64.2 0.1 1.2e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO FR47 PF08445.10 CDS29504.1 - 0.0011 18.9 0.0 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 CDS29504.1 - 0.0028 17.9 0.0 0.0044 17.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS29504.1 - 0.0096 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS29504.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sds3 PF08598.11 CDS29505.1 - 4.2e-10 40.0 13.5 7.6e-10 39.2 13.5 1.5 1 1 0 1 1 1 1 Sds3-like Baculo_PEP_C PF04513.12 CDS29505.1 - 0.063 13.3 1.1 3.5 7.7 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 CDS29505.1 - 0.095 12.0 3.3 0.21 10.9 3.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BORCS8 PF10167.9 CDS29505.1 - 0.1 12.6 1.1 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 DUF148 PF02520.17 CDS29505.1 - 0.12 12.5 2.2 2 8.6 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 Phasin PF05597.11 CDS29505.1 - 0.25 11.3 2.4 1.2 9.2 0.4 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.11 CDS29505.1 - 0.45 8.4 3.1 0.74 7.7 3.1 1.3 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 CDS29505.1 - 0.97 9.6 7.0 0.67 10.1 3.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 CDS29505.1 - 1.4 8.9 7.9 15 5.7 2.4 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding OCIA PF07051.11 CDS29506.1 - 1.8e-14 53.5 0.0 2.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) Innexin PF00876.18 CDS29507.1 - 6.3e-98 328.3 11.2 7.3e-98 328.1 11.2 1.0 1 0 0 1 1 1 1 Innexin Hum_adeno_E3A PF05393.11 CDS29507.1 - 0.67 10.0 4.3 0.65 10.0 1.0 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TGF_beta PF00019.20 CDS29508.1 - 3.2e-25 89.1 0.2 7.7e-25 87.9 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.18 CDS29508.1 - 1.3e-16 61.1 0.0 3.8e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 TGF-beta propeptide Axin_b-cat_bind PF08833.10 CDS29508.1 - 0.1 12.7 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Axin beta-catenin binding domain Fascin PF06268.13 CDS29509.1 - 3.9e-23 81.8 0.0 4.7e-13 49.3 0.0 4.5 3 1 2 5 5 5 2 Fascin domain FRG1 PF06229.12 CDS29509.1 - 0.00098 18.9 0.0 0.34 10.6 0.0 3.2 3 1 1 4 4 4 2 FRG1-like domain RicinB_lectin_2 PF14200.6 CDS29509.1 - 0.0053 17.5 0.0 1 10.1 0.0 3.5 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like LSM PF01423.22 CDS29510.1 - 5.5e-15 54.8 0.1 7.2e-15 54.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDS29510.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Hfq protein GRASP55_65 PF04495.14 CDS29511.1 - 6.5e-73 243.5 0.0 2.3e-53 180.2 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CDS29511.1 - 9.6e-08 32.2 0.0 0.00065 20.0 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDS29511.1 - 2.4e-05 24.1 0.1 0.088 12.7 0.1 2.8 2 1 0 2 2 2 2 PDZ domain Wtap PF17098.5 CDS29512.1 - 1.5e-31 109.4 0.1 1.5e-31 109.4 0.1 2.9 3 0 0 3 3 3 1 WTAP/Mum2p family AAA_31 PF13614.6 CDS29512.1 - 0.0034 17.3 1.3 0.022 14.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain GAS PF13851.6 CDS29512.1 - 0.032 13.6 11.9 0.18 11.1 1.5 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding NLRC4_HD PF17889.1 CDS29512.1 - 0.059 13.7 0.3 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 NLRC4 helical domain SLIDE PF09111.10 CDS29512.1 - 0.081 13.0 1.9 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 SLIDE KxDL PF10241.9 CDS29512.1 - 0.13 12.5 5.2 1.2 9.4 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein Fez1 PF06818.15 CDS29512.1 - 0.23 11.9 10.1 0.45 10.9 0.6 2.2 2 0 0 2 2 2 0 Fez1 FlaC_arch PF05377.11 CDS29512.1 - 0.23 11.9 4.4 7.1 7.1 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Med21 PF11221.8 CDS29512.1 - 0.37 11.0 9.5 0.069 13.4 1.6 2.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex bZIP_1 PF00170.21 CDS29512.1 - 2.5 8.2 13.0 0.088 12.9 3.5 2.8 3 0 0 3 3 3 0 bZIP transcription factor BLOC1_2 PF10046.9 CDS29513.1 - 3.3e-17 62.5 0.5 5.5e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.32 CDS29513.1 - 0.026 15.4 0.0 1.8 9.5 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DASH_Dad3 PF08656.10 CDS29513.1 - 0.059 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 Lipoprotein_20 PF13942.6 CDS29513.1 - 0.097 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Sec34 PF04136.15 CDS29513.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Sec34-like family GT-D PF08759.11 CDS29513.1 - 0.13 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold zf-H2C2_2 PF13465.6 CDS29514.1 - 2.6e-12 46.5 40.5 5.3e-07 29.8 2.9 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CDS29514.1 - 8.1e-09 35.5 45.4 0.0033 17.8 3.8 6.9 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29514.1 - 4.7e-08 33.2 44.2 0.081 13.8 0.5 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDS29514.1 - 1.9e-06 27.5 2.1 1.9e-06 27.5 2.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CDS29514.1 - 0.02 15.6 0.1 0.02 15.6 0.1 3.9 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CDS29514.1 - 0.029 14.7 14.9 0.35 11.2 0.6 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CDS29514.1 - 0.062 13.3 0.3 0.062 13.3 0.3 3.9 2 1 2 4 4 4 0 CpXC protein zf-C2HC_2 PF13913.6 CDS29514.1 - 9.8 6.2 12.1 1.2 9.1 0.0 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type MARVEL PF01284.23 CDS29515.1 - 9.7e-12 45.1 6.1 1.2e-11 44.8 6.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 CDS29515.1 - 0.084 12.7 1.5 0.13 12.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) UCH PF00443.29 CDS29516.2 - 6.4e-36 124.2 0.3 6.4e-36 124.2 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 CDS29516.2 - 1.9e-31 109.4 0.0 4.5e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CDS29516.2 - 7.6e-23 81.1 0.1 2.3e-22 79.5 0.1 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CDS29516.2 - 1.3e-17 63.9 0.0 4.7e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase UCH_1 PF13423.6 CDS29516.2 - 9.7e-11 41.8 0.6 3.1e-10 40.2 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase_fungal PF17667.1 CDS29516.2 - 0.001 17.9 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 CDS29517.1 - 4.6e-32 109.6 0.7 5.5e-16 58.1 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS29517.1 - 1.8e-14 53.6 0.3 3.6e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS29517.1 - 0.0017 18.4 0.3 0.041 13.9 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SAGA-Tad1 PF12767.7 CDS29517.1 - 0.015 15.0 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Orn_DAP_Arg_deC PF00278.22 CDS29519.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DEAD PF00270.29 CDS29520.1 - 1.7e-38 132.2 0.1 2.8e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS29520.1 - 8.3e-26 90.5 0.5 1.6e-23 83.2 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CDS29520.1 - 9e-09 35.0 0.1 2.6e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CDS29520.1 - 1.3e-07 31.8 0.0 2.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CDS29520.1 - 0.005 16.4 0.0 0.0086 15.6 0.0 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain NIF PF03031.18 CDS29520.1 - 0.044 13.5 1.7 0.07 12.9 0.7 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase AAA_19 PF13245.6 CDS29520.1 - 0.14 12.5 0.1 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain Na_H_Exchanger PF00999.21 CDS29521.1 - 5.7e-13 48.4 30.2 2.4e-07 29.9 2.5 2.8 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family MtrC PF04211.13 CDS29521.1 - 0.22 10.5 12.0 0.55 9.2 12.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Transposase_1 PF01359.18 CDS29522.1 - 4.1e-06 26.5 0.0 1.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) DNA_pol_phi PF04931.13 CDS29523.1 - 1.6e-11 43.1 48.8 2.7e-07 29.1 11.1 4.7 3 1 0 3 3 3 2 DNA polymerase phi Med19 PF10278.9 CDS29523.1 - 0.59 10.0 4.9 1 9.3 3.1 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Ribosomal_S18 PF01084.20 CDS29524.1 - 2.3e-12 46.9 0.0 4.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 DUF5318 PF17249.2 CDS29524.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Ribosomal_L14 PF00238.19 CDS29525.1 - 1.3e-12 47.8 0.1 2.7e-10 40.4 0.0 2.8 1 1 1 2 2 2 2 Ribosomal protein L14p/L23e Galactosyl_T PF01762.21 CDS29527.1 - 5.2e-22 78.6 0.1 8.9e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glycos_transf_2 PF00535.26 CDS29527.1 - 0.046 13.5 0.1 3.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 2 Transposase_1 PF01359.18 CDS29528.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.4 1 1 0 1 1 1 1 Transposase (partial DDE domain) zf-TRAF PF02176.18 CDS29529.1 - 1.8e-16 60.6 37.3 5.6e-12 46.2 4.6 3.9 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.16 CDS29529.1 - 1e-07 32.1 15.5 0.00044 20.3 1.4 2.6 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_6 PF14835.6 CDS29529.1 - 1.7e-06 27.8 3.6 1.7e-06 27.8 3.6 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CDS29529.1 - 0.00012 21.9 5.1 0.00012 21.9 5.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS29529.1 - 0.0003 20.6 6.7 0.0003 20.6 6.7 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS29529.1 - 0.0004 20.2 6.5 0.0004 20.2 6.5 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS29529.1 - 0.0065 16.4 6.7 0.0065 16.4 6.7 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDS29529.1 - 0.025 14.9 7.0 0.025 14.9 7.0 4.3 2 1 1 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 CDS29529.1 - 0.075 13.1 7.9 0.55 10.3 7.9 2.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS29529.1 - 0.37 11.0 11.8 0.13 12.4 7.5 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Kunitz_BPTI PF00014.23 CDS29530.1 - 1.1e-17 64.0 8.0 1.5e-17 63.6 8.0 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-ZPR1 PF03367.13 CDS29532.1 - 0.00076 19.4 0.0 0.00098 19.0 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain HECT PF00632.25 CDS29533.1 - 6.8e-11 42.2 0.0 7.2e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Deltameth_res PF16020.5 CDS29534.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Deltamethrin resistance AsnC_trans_reg2 PF17805.1 CDS29535.1 - 0.028 14.6 0.2 0.53 10.5 0.2 2.0 1 1 0 1 1 1 0 AsnC-like ligand binding domain DUF1462 PF07315.11 CDS29535.1 - 0.053 13.8 0.1 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) HECT PF00632.25 CDS29537.1 - 6.8e-11 42.2 0.0 7.2e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Deltameth_res PF16020.5 CDS29538.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Deltamethrin resistance AsnC_trans_reg2 PF17805.1 CDS29539.1 - 0.028 14.6 0.2 0.53 10.5 0.2 2.0 1 1 0 1 1 1 0 AsnC-like ligand binding domain DUF1462 PF07315.11 CDS29539.1 - 0.053 13.8 0.1 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) BAT2_N PF07001.11 CDS29541.1 - 1.9e-15 57.8 3.8 1.9e-15 57.8 3.8 10.2 7 3 2 11 11 11 1 BAT2 N-terminus Arf PF00025.21 CDS29542.1 - 1.8e-31 108.9 0.0 2e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDS29542.1 - 4.4e-10 39.4 0.0 4.9e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS29542.1 - 3.5e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDS29542.1 - 1.9e-05 24.0 0.0 3.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CDS29542.1 - 0.00024 20.6 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HJURP_C PF12347.8 CDS29542.1 - 0.037 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Ndc1_Nup PF09531.10 CDS29543.1 - 8.6e-16 57.8 9.5 6.6e-13 48.2 9.5 2.6 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 CDS29544.1 - 3.2e-07 30.1 0.0 6.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 CDS29544.1 - 0.02 14.8 0.2 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain GOLD_2 PF13897.6 CDS29545.2 - 1.9e-42 145.0 0.3 1.9e-42 145.0 0.3 2.1 2 1 1 3 3 3 1 Golgi-dynamics membrane-trafficking ACBP PF00887.19 CDS29545.2 - 4.7e-15 55.6 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein UQ_con PF00179.26 CDS29546.1 - 2.8e-43 146.9 0.0 3.2e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS29546.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B BAR PF03114.18 CDS29547.1 - 4.4e-22 78.9 0.2 5.8e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CDS29547.1 - 0.00086 18.5 0.9 0.0038 16.4 0.9 1.8 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CDS29548.1 - 9.1e-07 28.8 9.6 1e-06 28.6 9.6 1.0 1 0 0 1 1 1 1 BAR domain Uds1 PF15456.6 CDS29548.1 - 0.0057 16.8 5.2 0.03 14.5 3.3 2.2 2 0 0 2 2 2 1 Up-regulated During Septation CPG4 PF15481.6 CDS29548.1 - 0.028 15.1 2.8 0.028 15.1 2.8 2.8 2 1 1 3 3 3 0 Chondroitin proteoglycan 4 DUF1818 PF08848.11 CDS29548.1 - 0.033 14.3 0.4 0.05 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) SPT16 PF08644.11 CDS29548.1 - 0.066 13.4 1.5 0.11 12.7 1.5 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) OmpH PF03938.14 CDS29548.1 - 0.1 12.9 7.2 0.023 15.0 3.8 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 CDS29548.1 - 0.16 12.4 6.1 0.18 12.2 2.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 CDS29548.1 - 0.23 11.9 8.3 0.074 13.5 4.0 2.2 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uso1_p115_C PF04871.13 CDS29548.1 - 4.3 7.7 13.3 3.7 7.9 11.5 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlxA PF14282.6 CDS29548.1 - 4.5 7.3 15.3 0.25 11.3 9.6 1.9 2 1 0 2 2 2 0 FlxA-like protein UL42 PF17638.2 CDS29549.1 - 0.075 13.0 1.5 0.09 12.8 1.5 1.1 1 0 0 1 1 1 0 HCMV UL42 Pkinase PF00069.25 CDS29551.1 - 7.1e-65 219.0 0.0 1.1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CDS29551.1 - 2.3e-35 120.5 0.0 2e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CDS29551.1 - 2.9e-32 112.0 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29551.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF5044 PF16447.5 CDS29551.1 - 0.032 14.1 0.0 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) Seadorna_VP7 PF07387.11 CDS29551.1 - 0.097 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Nic96 PF04097.14 CDS29552.1 - 7.2e-124 414.5 0.0 1.1e-123 414.0 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Nup84_Nup100 PF04121.13 CDS29552.1 - 0.19 9.8 0.0 0.42 8.7 0.0 1.5 1 1 0 1 1 1 0 Nuclear pore protein 84 / 107 TMEM251 PF15190.6 CDS29554.1 - 0.33 10.9 3.1 0.52 10.3 1.1 2.3 1 1 1 2 2 2 0 Transmembrane protein 251 MCM_lid PF17855.1 CDS29558.1 - 5.6e-09 36.3 0.1 8.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain WES_acyltransf PF03007.16 CDS29559.1 - 0.094 12.5 4.0 0.12 12.2 0.1 2.6 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain BK_channel_a PF03493.18 CDS29560.1 - 5.7e-25 87.4 0.4 1.5e-24 86.0 0.1 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CDS29560.1 - 8.9e-13 48.0 4.5 8.9e-13 48.0 4.5 2.4 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 CDS29560.1 - 9.5e-08 31.6 18.2 9.5e-08 31.6 18.2 2.1 2 0 0 2 2 2 1 Ion transport protein DUF373 PF04123.13 CDS29560.1 - 4.6 6.6 7.8 1.9 7.8 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) C2 PF00168.30 CDS29562.1 - 3.5e-56 187.8 0.0 6.9e-29 100.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDS29562.1 - 3.5e-08 33.2 0.0 0.00084 18.9 0.0 2.7 1 1 1 2 2 2 2 CEP76 C2 domain DUF3989 PF13150.6 CDS29562.1 - 0.0079 15.9 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3989) DUF2232 PF09991.9 CDS29562.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TMEM154 PF15102.6 CDS29562.1 - 0.016 15.1 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family PDGLE PF13190.6 CDS29562.1 - 0.016 15.1 0.4 0.088 12.7 0.1 2.1 2 0 0 2 2 2 0 PDGLE domain SID-1_RNA_chan PF13965.6 CDS29562.1 - 0.2 10.0 0.1 0.3 9.5 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PY_rept_46 PF09689.10 CDS29562.1 - 0.48 11.0 3.9 0.93 10.1 2.3 2.3 1 1 1 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Adeno_E3_CR2 PF02439.15 CDS29562.1 - 0.89 9.4 3.7 0.56 10.0 1.5 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Cadherin PF00028.17 CDS29563.1 - 1.1e-71 237.3 8.4 1.5e-12 47.8 0.0 8.1 7 2 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS29563.1 - 2e-07 30.7 2.5 0.028 14.2 0.2 5.4 4 1 0 4 4 4 2 Cadherin-like Y_Y_Y PF07495.13 CDS29563.1 - 0.011 15.7 0.0 0.33 10.9 0.0 3.0 3 0 0 3 3 3 0 Y_Y_Y domain Cadherin_3 PF16184.5 CDS29563.1 - 0.011 15.7 7.1 12 6.0 0.0 5.7 5 1 1 6 6 6 0 Cadherin-like Aldedh PF00171.22 CDS29564.1 - 1.6e-56 191.7 0.0 2.2e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S21e PF01249.18 CDS29565.1 - 1.1e-32 112.0 0.0 1.2e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pkinase_Tyr PF07714.17 CDS29567.1 - 3.4e-68 229.7 0.0 4.4e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS29567.1 - 4.5e-35 121.3 0.0 6.8e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH3_1 PF00018.28 CDS29567.1 - 2.5e-11 43.0 0.0 5.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH2 PF00017.24 CDS29567.1 - 4.9e-11 42.6 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CDS29567.1 - 1.3e-08 34.6 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS29567.1 - 4.4e-06 26.3 0.0 2.2e-05 24.1 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain Haspin_kinase PF12330.8 CDS29567.1 - 0.11 11.4 0.1 0.22 10.4 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CDS29567.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CDI PF02234.19 CDS29569.1 - 0.014 15.6 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor RT_RNaseH PF17917.1 CDS29570.1 - 1.6e-19 70.2 0.0 4.3e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS29570.1 - 2.1e-18 66.2 0.0 3.7e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS29570.1 - 1.4e-13 51.0 0.0 2.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS29570.1 - 8.6e-08 32.2 0.6 2e-07 31.0 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CDS29570.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WH2 PF02205.20 CDS29571.1 - 0.0031 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 WH2 motif PAT1 PF09770.9 CDS29571.1 - 0.75 8.0 12.3 1 7.5 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CDS29571.1 - 1.9 8.4 16.0 3.6 7.5 16.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kelch_1 PF01344.25 CDS29573.1 - 5.3e-23 80.3 1.0 2.7e-13 49.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CDS29573.1 - 4.5e-12 45.8 0.0 8.7e-09 35.3 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CDS29573.1 - 7.5e-11 41.9 0.2 6.5e-06 26.3 0.0 3.7 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CDS29573.1 - 7.8e-10 38.5 1.0 0.00045 20.2 0.0 4.0 5 0 0 5 5 5 2 Kelch motif BACK PF07707.15 CDS29573.1 - 6.4e-08 32.6 0.1 1.2e-05 25.3 0.1 2.3 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_3 PF13415.6 CDS29573.1 - 1.1e-06 28.8 0.1 0.0013 18.9 0.0 3.9 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS29573.1 - 0.00015 21.6 0.0 0.029 14.3 0.0 3.2 4 0 0 4 4 4 1 Kelch motif BTB PF00651.31 CDS29573.1 - 0.00046 20.4 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NAD_Gly3P_dh_C PF07479.14 CDS29574.1 - 1.1e-31 110.1 0.0 2.5e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CDS29574.1 - 4e-26 91.9 0.0 1.4e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 CDS29574.1 - 0.001 19.6 0.9 0.018 15.6 0.6 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CDS29574.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DSPn PF14671.6 CDS29575.1 - 1.5e-52 177.8 2.9 1.2e-51 174.9 2.2 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CDS29575.1 - 7.3e-16 58.2 0.1 8e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS29575.1 - 9.6e-05 22.5 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDS29575.1 - 0.0002 21.0 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BING4CT PF08149.11 CDS29576.1 - 8.2e-31 105.7 0.0 4.2e-29 100.2 0.0 3.3 3 1 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CDS29576.1 - 3.3e-09 37.2 2.1 7.6e-05 23.4 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS29576.1 - 8.2e-05 22.8 0.0 1.5 9.2 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mt_ATP-synt_D PF05873.12 CDS29576.1 - 0.0017 18.2 2.0 0.0031 17.4 2.0 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Coatomer_WDAD PF04053.14 CDS29576.1 - 0.019 14.0 0.1 0.11 11.6 0.0 2.0 2 1 1 3 3 3 0 Coatomer WD associated region ecTbetaR2 PF08917.10 CDS29576.1 - 0.067 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain DUF4427 PF14468.6 CDS29576.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Myb_DNA-bind_7 PF15963.5 CDS29577.1 - 7.1e-08 32.2 0.3 0.0047 16.8 0.1 2.5 2 0 0 2 2 2 2 Myb DNA-binding like ELM2 PF01448.24 CDS29577.1 - 1.4e-07 32.1 0.2 0.00012 22.8 0.0 3.0 2 0 0 2 2 2 2 ELM2 domain Myb_DNA-binding PF00249.31 CDS29577.1 - 9.3e-06 25.7 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain UPF0223 PF05256.12 CDS29577.1 - 0.069 13.5 0.2 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) BRE1 PF08647.11 CDS29578.1 - 0.00011 22.2 13.0 0.00011 22.2 13.0 10.5 3 3 5 10 10 10 4 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 CDS29578.1 - 0.013 15.5 2.9 0.013 15.5 2.9 8.3 6 3 2 8 8 8 0 Short coiled-coil protein Peptidase_C78 PF07910.13 CDS29579.1 - 1.5e-43 148.8 0.0 2.3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 XLF PF09302.11 CDS29579.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component NAD_Gly3P_dh_C PF07479.14 CDS29580.1 - 5.3e-10 39.7 0.4 1.6e-09 38.2 0.3 1.8 1 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PIN_3 PF13470.6 CDS29580.1 - 0.064 14.0 1.1 13 6.6 0.2 2.3 2 0 0 2 2 2 0 PIN domain MFS_1 PF07690.16 CDS29581.1 - 4.5e-26 91.6 78.6 5e-21 75.0 48.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ig_3 PF13927.6 CDS29582.2 - 2.1e-55 185.2 3.2 1.6e-12 47.8 0.0 13.1 12 0 0 12 12 12 9 Immunoglobulin domain I-set PF07679.16 CDS29582.2 - 4.8e-50 167.6 0.0 1.6e-19 69.7 0.0 10.0 11 0 0 11 11 10 6 Immunoglobulin I-set domain Pkinase PF00069.25 CDS29582.2 - 2.4e-43 148.4 0.0 1.1e-36 126.5 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain ig PF00047.25 CDS29582.2 - 2.8e-29 101.1 0.2 1.1e-10 41.5 0.0 8.7 8 0 0 8 8 8 4 Immunoglobulin domain fn3 PF00041.21 CDS29582.2 - 4.3e-24 84.7 1.3 6.2e-06 26.5 0.1 6.4 6 0 0 6 6 6 4 Fibronectin type III domain Ig_2 PF13895.6 CDS29582.2 - 1.2e-21 76.8 2.5 1.3e-05 25.5 0.0 8.9 11 0 0 11 11 11 4 Immunoglobulin domain Pkinase_Tyr PF07714.17 CDS29582.2 - 4.5e-13 49.1 0.0 1.2e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase V-set PF07686.17 CDS29582.2 - 2.2e-11 43.9 0.2 0.0041 17.3 0.0 7.3 8 0 0 8 8 8 2 Immunoglobulin V-set domain CopG_antitoxin PF12441.8 CDS29582.2 - 9e-11 42.2 4.6 1.1e+02 3.4 0.0 9.8 9 0 0 9 9 9 0 CopG antitoxin of type II toxin-antitoxin system RhoGEF PF00621.20 CDS29582.2 - 1.7e-09 38.2 1.6 4.2e-09 36.9 1.6 1.7 1 0 0 1 1 1 1 RhoGEF domain Kdo PF06293.14 CDS29582.2 - 0.0006 19.2 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS29582.2 - 0.0032 16.8 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Pur_ac_phosph_N PF16656.5 CDS29582.2 - 0.015 15.9 0.1 2 9.0 0.0 4.0 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain C1-set PF07654.15 CDS29582.2 - 0.016 15.6 0.1 1.9 9.0 0.0 4.0 4 0 0 4 4 2 0 Immunoglobulin C1-set domain Ig_6 PF18452.1 CDS29582.2 - 0.087 12.4 0.0 0.73 9.4 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain Lig_chan-Glu_bd PF10613.9 CDS29583.1 - 9e-36 122.6 0.0 4.6e-35 120.3 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 CDS29583.1 - 6.6e-33 113.7 0.0 1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDS29583.1 - 1.9e-16 60.2 0.0 3.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ANF_receptor PF01094.28 CDS29583.1 - 1.2e-10 41.1 0.0 3.8e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region Ion_trans_2 PF07885.16 CDS29583.1 - 3.3 7.8 8.0 0.68 9.9 0.5 2.7 2 0 0 2 2 2 0 Ion channel IDO PF01231.18 CDS29584.1 - 2.4e-79 267.2 0.0 3.7e-78 263.2 0.0 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 CDS29584.1 - 4.5e-05 22.4 0.0 0.051 12.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) SH3_1 PF00018.28 CDS29585.1 - 2.9e-31 106.8 0.1 4e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CDS29585.1 - 2.5e-28 97.7 0.0 2.7e-16 59.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CDS29585.1 - 4.8e-22 77.4 0.0 2.8e-13 49.3 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.24 CDS29585.1 - 1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 SH2 domain DUF5348 PF17295.2 CDS29585.1 - 0.018 14.9 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) SH3_3 PF08239.11 CDS29585.1 - 0.069 13.4 0.1 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4648 PF15505.6 CDS29585.1 - 0.075 13.9 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) RRM_1 PF00076.22 CDS29586.1 - 8.5e-12 44.7 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 CDS29586.1 - 3.1e-07 30.0 0.7 3.1e-07 30.0 0.7 2.2 2 0 0 2 2 2 1 SAP domain DUF5086 PF16985.5 CDS29586.1 - 0.089 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) DUF126 PF01989.16 CDS29586.1 - 0.21 11.4 0.1 0.64 9.8 0.0 1.7 2 0 0 2 2 2 0 Aconitase X swivel domain Menin PF05053.13 CDS29586.1 - 9.3 4.5 8.8 16 3.6 8.8 1.3 1 0 0 1 1 1 0 Menin HTH_24 PF13412.6 CDS29587.1 - 0.00052 19.5 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 CDS29587.1 - 0.0016 18.2 0.0 0.0052 16.6 0.1 1.8 2 0 0 2 2 2 1 HTH DNA binding domain HTH_11 PF08279.12 CDS29587.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 CDS29587.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ANT PF03374.14 CDS29587.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.8 2 1 0 2 2 2 0 Phage antirepressor protein KilAC domain MarR PF01047.22 CDS29587.1 - 0.026 14.4 0.1 0.071 13.1 0.0 1.8 2 0 0 2 2 2 0 MarR family Dcc1 PF09724.9 CDS29587.1 - 0.027 13.8 0.1 0.03 13.6 0.1 1.4 1 1 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 HTH_DeoR PF08220.12 CDS29587.1 - 0.038 13.7 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 CDS29587.1 - 0.045 13.6 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family IF2_N PF04760.15 CDS29587.1 - 0.09 12.6 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MarR_2 PF12802.7 CDS29587.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 CDS29587.1 - 0.18 12.2 0.1 0.71 10.3 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator IF-2B PF01008.17 CDS29589.1 - 2.1e-52 178.1 0.0 4.4e-52 177.0 0.0 1.6 2 0 0 2 2 2 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 CDS29589.1 - 0.019 13.7 5.6 0.024 13.3 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3584 PF12128.8 CDS29589.1 - 2.1 5.7 18.0 2.9 5.3 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tubulin PF00091.25 CDS29590.1 - 1e-65 221.7 0.0 1.4e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS29590.1 - 5.3e-49 165.6 0.0 8.2e-49 165.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS29590.1 - 0.00019 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pkinase_Tyr PF07714.17 CDS29591.2 - 6.3e-108 359.9 0.0 4.1e-68 229.5 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CDS29591.2 - 1.1e-62 211.9 0.0 2e-42 145.4 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Kinase-like PF14531.6 CDS29591.2 - 5e-05 22.8 0.0 0.00051 19.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDS29591.2 - 5e-05 22.7 0.1 0.3 10.4 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS29591.2 - 7.4e-05 21.9 0.2 0.0023 16.9 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 CDS29591.2 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDS29591.2 - 0.17 11.8 0.3 1.5 8.7 0.3 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family MOR2-PAG1_N PF14222.6 CDS29592.1 - 2.4e-123 413.0 2.7 4e-74 250.5 3.4 2.3 1 1 1 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CDS29592.1 - 5.8e-27 95.2 0.0 2.3e-12 47.3 0.0 3.7 3 0 0 3 3 3 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CDS29592.1 - 6.5e-07 27.4 0.7 0.35 8.4 0.0 3.2 3 0 0 3 3 3 3 Cell morphogenesis central region V_ATPase_I PF01496.19 CDS29593.1 - 0 1039.3 3.5 0 1039.2 3.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TssC PF17541.2 CDS29593.1 - 0.26 10.1 1.4 2.5 6.8 0.2 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB ELFV_dehydrog_N PF02812.18 CDS29594.1 - 7e-57 190.9 0.0 1.1e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CDS29594.1 - 1.8e-54 185.1 0.0 5e-53 180.3 0.0 2.1 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 CDS29594.1 - 0.0047 16.3 0.0 0.013 14.9 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CDS29594.1 - 0.0064 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ge1_WD40 PF16529.5 CDS29595.1 - 2.1e-21 76.2 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Apolipoprotein PF01442.18 CDS29595.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF445 PF04286.12 CDS29595.1 - 0.037 13.8 5.1 0.031 14.1 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF445) B56 PF01603.20 CDS29595.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) APG17 PF04108.12 CDS29595.1 - 0.083 12.0 2.3 0.2 10.7 0.2 2.4 3 0 0 3 3 3 0 Autophagy protein Apg17 HEPN_AbiU2 PF18734.1 CDS29595.1 - 0.14 11.7 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 AbiU2 Acid_PPase PF12689.7 CDS29595.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Acid Phosphatase Baculo_PEP_C PF04513.12 CDS29595.1 - 0.49 10.4 26.8 0.12 12.4 0.3 4.6 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 CDS29595.1 - 1.3 9.4 11.4 1.9 8.9 0.4 3.7 2 1 1 3 3 3 0 YlqD protein Exonuc_VII_L PF02601.15 CDS29595.1 - 1.6 8.3 6.5 4.8 6.7 0.2 2.6 1 1 0 2 2 2 0 Exonuclease VII, large subunit Sgf11 PF08209.11 CDS29596.1 - 4.7e-11 42.1 1.7 8.2e-11 41.3 1.7 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) LSDAT_euk PF18139.1 CDS29597.1 - 6.2e-38 130.7 0.0 1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM adh_short PF00106.25 CDS29597.1 - 3.2e-11 43.0 0.0 6.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ion_trans PF00520.31 CDS29597.1 - 7.6e-06 25.3 15.1 3.8e-05 23.0 15.1 2.0 1 1 0 1 1 1 1 Ion transport protein LSDAT_prok PF18171.1 CDS29597.1 - 1.3e-05 24.6 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote adh_short_C2 PF13561.6 CDS29597.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS29597.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Ank_5 PF13857.6 CDS29597.1 - 0.092 13.1 0.0 1.4 9.3 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Epimerase PF01370.21 CDS29597.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BSD PF03909.17 CDS29598.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 BSD domain YceD PF02620.17 CDS29598.1 - 1.3 9.2 5.7 0.15 12.2 1.1 1.8 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Defensin_propep PF00879.18 CDS29598.1 - 5.2 7.4 9.5 5.5 7.3 0.0 3.6 2 1 1 3 3 3 0 Defensin propeptide Ribosomal_L7Ae PF01248.26 CDS29600.1 - 3.9e-22 77.8 0.0 4.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynein_light PF01221.18 CDS29601.1 - 1.4e-40 137.5 1.7 1.5e-40 137.4 1.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 CDS29601.1 - 0.11 12.5 1.4 0.17 11.8 0.7 1.7 1 1 0 1 1 1 0 Ectatomin E1_dh PF00676.20 CDS29602.1 - 2.9e-109 364.6 0.0 2.9e-109 364.6 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component Proteasome PF00227.26 CDS29602.1 - 1.5e-44 151.8 0.1 2.7e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 CDS29602.1 - 9.3e-10 39.3 0.4 2.1e-09 38.2 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3752 PF12572.8 CDS29602.1 - 4.5e-08 33.8 18.5 0.0021 18.6 16.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3752) SR-25 PF10500.9 CDS29602.1 - 4.6e-06 26.4 24.6 1e-05 25.3 24.6 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Metallophos_2 PF12850.7 CDS29602.1 - 8.2e-05 22.8 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DXP_synthase_N PF13292.6 CDS29602.1 - 0.02 14.1 1.3 0.043 13.0 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase AF-4 PF05110.13 CDS29602.1 - 0.15 10.1 16.4 0.23 9.5 16.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Vfa1 PF08432.10 CDS29602.1 - 0.3 11.4 17.2 0.61 10.4 17.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_S18 PF01084.20 CDS29602.1 - 0.39 11.0 1.9 1.1 9.6 1.6 1.9 2 0 0 2 2 2 0 Ribosomal protein S18 LCD1 PF09798.9 CDS29602.1 - 0.67 8.4 3.6 0.95 7.9 3.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein PP2C PF00481.21 CDS29603.1 - 1.5e-22 80.5 0.0 4.8e-21 75.6 0.0 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C NUDIX PF00293.28 CDS29604.1 - 9.8e-16 58.0 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 CDS29604.1 - 5.7e-13 49.0 0.3 1.2e-12 48.0 0.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain PNTB PF02233.16 CDS29605.2 - 1.2e-177 591.4 15.6 1.2e-177 591.4 15.6 2.3 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDS29605.2 - 4.5e-110 366.0 3.1 3.9e-64 215.9 1.6 3.6 3 0 0 3 3 3 3 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CDS29605.2 - 1.1e-43 148.8 0.0 2.5e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CDS29605.2 - 1.1e-31 109.0 6.0 1.1e-31 109.0 6.0 4.6 3 1 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CDS29605.2 - 0.0041 16.5 0.3 0.96 8.8 0.1 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CDS29605.2 - 0.0063 16.5 0.5 0.068 13.1 0.2 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 CDS29605.2 - 0.017 14.3 0.4 0.038 13.2 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDS29605.2 - 0.36 11.4 1.7 0.95 10.1 0.8 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDS29605.2 - 0.38 11.0 5.1 0.55 10.5 0.9 3.5 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Phage_holin_2_4 PF16082.5 CDS29605.2 - 1.6 8.5 3.5 1 9.2 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like ANF_receptor PF01094.28 CDS29607.1 - 4.2e-68 230.0 0.0 6.4e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CDS29607.1 - 3.3e-47 161.2 19.8 6.4e-47 160.3 19.8 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 CDS29607.1 - 3.3e-10 39.8 12.9 7.5e-10 38.6 12.9 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.6 CDS29607.1 - 1.8e-07 31.1 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein BORA_N PF15280.6 CDS29607.1 - 0.032 13.9 0.4 0.065 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein aurora borealis N-terminus Neur_chan_LBD PF02931.23 CDS29608.2 - 3.2e-54 183.6 0.7 6.8e-54 182.6 0.7 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS29608.2 - 1.7e-30 106.8 0.8 2.6e-30 106.3 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region NHS PF15273.6 CDS29608.2 - 0.053 12.6 3.1 0.072 12.2 3.1 1.1 1 0 0 1 1 1 0 NHS-like LHC PF00556.20 CDS29608.2 - 0.056 13.7 2.0 0.17 12.1 2.0 1.8 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit PIG-Y PF15159.6 CDS29608.2 - 0.16 12.9 6.4 4.7 8.2 0.6 3.5 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF5090 PF17009.5 CDS29608.2 - 9.4 6.1 8.4 0.77 9.7 1.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) polyprenyl_synt PF00348.17 CDS29609.1 - 3e-08 33.1 0.0 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CDS29610.2 - 2.9e-61 207.2 0.0 4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29610.2 - 7.2e-27 94.3 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29610.2 - 0.00053 19.4 0.5 0.0022 17.4 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CDS29610.2 - 0.064 12.2 0.0 0.064 12.2 0.0 2.3 3 0 0 3 3 3 0 Haspin like kinase domain EcKinase PF02958.20 CDS29610.2 - 0.079 12.3 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.14 CDS29610.2 - 0.12 11.7 0.0 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDS29610.2 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ABC_membrane PF00664.23 CDS29611.2 - 1.8e-65 221.3 33.7 5.2e-39 134.5 7.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDS29611.2 - 4e-31 108.3 0.0 1e-30 107.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter RPN13_C PF16550.5 CDS29611.2 - 4.8e-26 91.1 1.1 9e-26 90.2 1.1 1.5 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 CDS29611.2 - 1.3e-23 83.3 0.0 2.8e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SMC_N PF02463.19 CDS29611.2 - 6.2e-06 25.8 0.5 0.0065 15.9 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDS29611.2 - 0.0017 18.2 0.3 1.3 8.8 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDS29611.2 - 0.019 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDS29611.2 - 0.042 14.2 0.2 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 CDS29611.2 - 0.059 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CDS29611.2 - 0.082 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1761 PF08570.10 CDS29611.2 - 0.21 11.9 0.1 0.21 11.9 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1761) Dynein_C PF18199.1 CDS29614.2 - 4.3e-49 167.4 0.0 4.6e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain LCAT PF02450.15 CDS29615.2 - 2.2e-47 162.1 0.5 2.7e-41 142.0 0.1 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CDS29615.2 - 0.0026 17.0 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 CDS29615.2 - 0.0051 15.9 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 CDS29615.2 - 0.018 15.6 0.0 0.033 14.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDS29615.2 - 0.091 12.4 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 CDS29615.2 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 CDS29615.2 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase La PF05383.17 CDS29617.1 - 1.2e-06 28.4 0.1 2.2e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 La domain FoP_duplication PF13865.6 CDS29618.1 - 3.2e-07 30.8 6.5 3.2e-07 30.8 6.5 1.9 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 PROCN PF08083.11 CDS29621.1 - 6.6e-233 772.7 9.4 6.6e-233 772.7 9.4 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CDS29621.1 - 9.5e-129 427.8 0.8 1.6e-128 427.1 0.8 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CDS29621.1 - 7.4e-90 299.0 2.7 7.4e-90 299.0 2.7 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDS29621.1 - 6.7e-84 279.4 4.5 1.8e-83 278.0 4.5 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDS29621.1 - 3.3e-70 234.4 0.0 7e-70 233.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CDS29621.1 - 9.4e-52 174.1 0.0 2.4e-51 172.8 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CDS29621.1 - 8.1e-47 157.5 1.1 2.1e-46 156.2 1.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CDS29621.1 - 1.2e-09 38.2 0.0 2.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Spectrin PF00435.21 CDS29622.1 - 0 1282.8 229.3 3.4e-29 101.4 0.5 22.1 22 0 0 22 22 22 21 Spectrin repeat EFhand_Ca_insen PF08726.10 CDS29622.1 - 3.5e-23 81.5 2.0 3.5e-23 81.5 2.0 3.5 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CDS29622.1 - 6.7e-15 53.4 0.8 1.9e-06 27.0 0.2 3.5 2 0 0 2 2 2 2 EF hand SH3_1 PF00018.28 CDS29622.1 - 5.7e-13 48.3 1.4 7.2e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain EF-hand_6 PF13405.6 CDS29622.1 - 4.9e-12 44.7 0.5 3.4e-05 23.4 0.2 4.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDS29622.1 - 6.8e-12 45.7 6.1 3.9e-11 43.2 0.2 4.6 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS29622.1 - 1.2e-08 34.6 0.0 0.015 15.2 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair SH3_9 PF14604.6 CDS29622.1 - 1.8e-08 34.1 0.0 4.8e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_5 PF13202.6 CDS29622.1 - 1.3e-07 30.7 0.1 0.027 14.0 0.0 3.6 3 0 0 3 3 3 2 EF hand SH3_2 PF07653.17 CDS29622.1 - 4e-05 23.2 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CDS29622.1 - 0.0059 16.6 0.7 0.031 14.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain HOCHOB PF17943.1 CDS29622.1 - 0.91 10.3 4.9 18 6.1 0.3 4.8 4 0 0 4 4 4 0 Homeobox-cysteine loop-homeobox GPCR_chapero_1 PF11904.8 CDS29623.1 - 2.1e-78 263.9 0.0 3.4e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 CDS29623.1 - 4.1e-06 27.3 0.0 9.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDS29623.1 - 0.00021 21.6 0.2 0.0013 19.1 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CDS29623.1 - 0.00083 19.6 0.1 0.0037 17.5 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29623.1 - 0.0099 16.3 0.1 0.22 12.2 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat Actin PF00022.19 CDS29624.1 - 1.8e-47 161.9 0.0 1.2e-39 136.1 0.0 2.4 1 1 1 2 2 2 2 Actin Herpes_UL92 PF03048.14 CDS29624.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 UL92 family Peptidase_C12 PF01088.21 CDS29625.1 - 8.3e-50 169.4 0.5 2.1e-32 112.6 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDS29625.1 - 1.5e-15 56.8 0.2 3.7e-15 55.5 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Ribosomal_L11_N PF03946.14 CDS29626.1 - 6.5e-24 83.5 0.9 9.1e-24 83.1 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDS29626.1 - 1.8e-18 66.8 0.9 3.2e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RNase_T PF00929.24 CDS29627.1 - 3.7e-16 60.1 0.0 4.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CDS29627.1 - 6.8e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 1 0 1 1 1 1 3'-5' exonuclease RNase_T PF00929.24 CDS29628.1 - 2e-29 103.3 0.0 1.4e-13 51.7 0.0 2.2 2 0 0 2 2 2 2 Exonuclease DNA_pol_A_exo1 PF01612.20 CDS29628.1 - 6.2e-06 26.0 0.0 0.0043 16.8 0.0 2.8 2 1 0 2 2 2 2 3'-5' exonuclease DUF1882 PF08966.11 CDS29628.1 - 0.00049 20.3 2.5 1.5 9.1 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF1882) sCache_like PF16736.5 CDS29628.1 - 0.092 12.8 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Single Cache-like RNase_T PF00929.24 CDS29629.1 - 1.6e-10 41.7 0.0 2.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease LSM PF01423.22 CDS29630.1 - 1.1e-15 57.0 0.0 1.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDS29630.1 - 0.089 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain G-alpha PF00503.20 CDS29631.1 - 8.1e-37 127.2 4.5 9.7e-37 126.9 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-C2H2 PF00096.26 CDS29632.1 - 6.3e-08 32.7 8.7 0.00066 20.0 3.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29632.1 - 5.8e-05 23.6 11.6 0.038 14.8 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 CDS29632.1 - 0.00014 22.2 3.3 0.0019 18.6 0.0 2.5 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CDS29632.1 - 0.012 15.6 6.0 0.019 14.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS29632.1 - 0.073 13.4 5.1 0.82 10.0 0.4 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDS29632.1 - 1.2 9.5 6.9 7.1 7.0 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CDS29632.1 - 2.4 8.7 10.8 5.2 7.7 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger double domain LIM PF00412.22 CDS29634.1 - 6.6e-15 55.1 5.5 7.3e-15 54.9 5.5 1.0 1 0 0 1 1 1 1 LIM domain zf-ACC PF17848.1 CDS29634.1 - 0.0047 17.0 3.0 0.24 11.5 0.4 2.5 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain YacG PF03884.14 CDS29634.1 - 0.011 15.4 3.5 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn_Tnp_IS1595 PF12760.7 CDS29634.1 - 0.022 14.7 3.9 0.022 14.7 3.9 1.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 CDS29634.1 - 0.029 14.0 3.4 1.6 8.4 1.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.6 CDS29634.1 - 0.17 11.6 0.7 0.17 11.6 0.7 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 CDS29634.1 - 0.2 11.3 12.8 0.3 10.7 2.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2072 PF09845.9 CDS29634.1 - 3.7 7.8 5.9 5 7.4 2.2 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein Zn-ribbon_8 PF09723.10 CDS29634.1 - 3.7 7.7 9.0 3.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain EF-hand_2 PF09068.11 CDS29635.1 - 1.7e-27 96.0 0.1 3.2e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 CDS29635.1 - 2.2e-13 50.4 0.1 6.1e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand ZZ PF00569.17 CDS29635.1 - 2e-12 46.7 3.4 3.4e-12 45.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 CDS29635.1 - 0.00043 20.5 5.0 0.00047 20.4 3.2 2.0 2 0 0 2 2 2 1 C1 domain APG6_N PF17675.1 CDS29635.1 - 0.61 10.6 8.4 6.8 7.2 0.7 3.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Ank_5 PF13857.6 CDS29636.1 - 8.6e-34 115.2 8.3 1.5e-08 34.8 0.3 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS29636.1 - 3.2e-32 110.9 4.6 4.7e-13 49.5 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29636.1 - 5.6e-28 96.9 4.4 1.9e-09 37.8 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29636.1 - 2.3e-27 92.0 6.2 1.9e-05 24.6 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 CDS29636.1 - 5.8e-25 86.6 9.7 2.4e-06 27.7 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat RRM_1 PF00076.22 CDS29637.1 - 1.5e-28 98.4 0.0 3.3e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 CDS29637.1 - 0.076 13.9 4.4 0.14 13.0 4.4 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins FAD_binding_8 PF08022.12 CDS29639.2 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain Prefoldin_2 PF01920.20 CDS29640.1 - 6.1e-20 71.1 4.2 7.4e-20 70.9 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit PABP PF00658.18 CDS29640.1 - 0.061 13.5 0.5 1.1 9.5 0.1 2.2 1 1 1 2 2 2 0 Poly-adenylate binding protein, unique domain Selenoprotein_S PF06936.11 CDS29640.1 - 0.098 12.5 2.1 0.084 12.7 0.8 1.5 1 1 0 1 1 1 0 Selenoprotein S (SelS) HDV_ag PF01517.18 CDS29640.1 - 1 9.1 6.2 0.65 9.8 2.8 2.0 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen TSP_3 PF02412.18 CDS29641.2 - 0.0016 18.1 6.0 0.0016 18.1 6.0 56.8 28 17 28 58 58 58 37 Thrombospondin type 3 repeat Septin PF00735.18 CDS29642.2 - 2.3e-83 279.7 3.7 2.3e-83 279.7 3.7 1.8 2 0 0 2 2 2 1 Septin DUF4922 PF16269.5 CDS29642.2 - 0.052 13.3 0.6 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) Atg14 PF10186.9 CDS29642.2 - 1.1 8.3 15.4 1.7 7.6 15.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myelin_PLP PF01275.19 CDS29646.1 - 3.6e-06 27.0 7.2 6e-05 23.0 3.0 2.1 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) FA_desaturase PF00487.24 CDS29646.1 - 0.34 10.7 4.0 0.23 11.3 1.2 2.0 2 0 0 2 2 2 0 Fatty acid desaturase 7tm_1 PF00001.21 CDS29647.1 - 1.3e-58 198.4 5.5 2.5e-58 197.5 5.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS29647.1 - 4.4e-12 45.9 9.7 6.2e-09 35.6 4.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS29647.1 - 6.1e-07 29.3 10.1 6.1e-07 29.3 10.1 2.2 3 1 1 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 CDS29647.1 - 0.0011 18.5 2.0 0.0029 17.2 2.0 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srbc 7TM_GPCR_Srv PF10323.9 CDS29647.1 - 0.0034 16.8 10.2 0.004 16.5 3.3 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv Exo_endo_phos_2 PF14529.6 CDS29648.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Glyco_transf_22 PF03901.17 CDS29650.2 - 8.4e-48 163.6 25.6 1.1e-47 163.3 25.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1011 PF06237.12 CDS29650.2 - 0.0023 18.2 2.4 0.0079 16.5 2.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1011) SIR2 PF02146.17 CDS29651.1 - 7.7e-23 81.3 0.0 1e-18 67.9 0.0 3.1 2 1 0 2 2 2 1 Sir2 family Sld5 PF05916.11 CDS29652.1 - 0.00021 21.7 0.1 0.00038 20.9 0.1 1.5 1 1 0 1 1 1 1 GINS complex protein His_Phos_1 PF00300.22 CDS29653.1 - 1.3e-07 31.6 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 CDS29654.1 - 5.8e-08 32.7 0.0 1.6e-07 31.2 0.0 1.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Cnd2 PF05786.14 CDS29655.2 - 7.2e-105 352.3 0.5 1.1e-104 351.8 0.5 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 PIN7 PF18475.1 CDS29655.2 - 0.023 15.3 0.0 0.06 14.0 0.0 1.6 1 0 0 1 1 1 0 PIN domain CNDH2_N PF06278.11 CDS29655.2 - 0.088 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal LIM PF00412.22 CDS29656.1 - 1.2e-29 102.2 18.5 2.1e-16 59.9 2.6 2.1 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 CDS29656.1 - 1 9.4 14.8 3.1e+02 1.5 14.8 3.3 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 CDS29656.1 - 2.8 7.9 15.1 1.4 8.9 1.3 3.4 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sec1 PF00995.23 CDS29659.1 - 3.2e-122 409.7 0.0 3.7e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_transf_10 PF00852.19 CDS29659.1 - 0.058 13.1 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Cullin_binding PF03556.15 CDS29659.1 - 0.13 12.7 0.4 0.3 11.6 0.4 1.5 1 0 0 1 1 1 0 Cullin binding DUF3417 PF11897.8 CDS29659.1 - 0.21 12.1 0.8 0.52 10.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Homeodomain PF00046.29 CDS29660.1 - 8.9e-19 67.1 0.7 1.7e-18 66.2 0.7 1.5 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 CDS29660.1 - 4.2e-17 62.1 20.2 1.4e-09 38.0 7.9 2.3 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CDS29660.1 - 0.00025 20.9 0.2 0.009 15.9 0.1 2.5 2 0 0 2 2 2 1 Homeobox KN domain LSM_int_assoc PF16605.5 CDS29660.1 - 0.044 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 LSM-interacting associated unstructured SIX1_SD PF16878.5 CDS29661.1 - 4.2e-42 143.2 0.1 6.9e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDS29661.1 - 6.7e-12 45.1 3.2 8.9e-12 44.7 0.7 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDS29661.1 - 1.5e-09 37.6 1.5 1.5e-09 37.6 1.5 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 CDS29661.1 - 0.0055 16.2 0.1 0.07 12.6 0.1 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DnaJ PF00226.31 CDS29662.1 - 6.3e-05 23.0 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CDS29662.1 - 9.1e-05 22.5 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 Taeniidae_ag PF05596.11 CDS29664.1 - 7.5e-27 93.1 0.3 9.3e-27 92.8 0.3 1.1 1 0 0 1 1 1 1 Taeniidae antigen DUF4969 PF16339.5 CDS29664.1 - 0.067 13.6 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Taeniidae_ag PF05596.11 CDS29665.1 - 1.5e-26 92.2 2.0 1.7e-26 91.9 2.0 1.1 1 0 0 1 1 1 1 Taeniidae antigen Taeniidae_ag PF05596.11 CDS29666.1 - 1.5e-27 95.3 4.9 1.8e-27 95.1 4.9 1.1 1 0 0 1 1 1 1 Taeniidae antigen FH2 PF02181.23 CDS29666.1 - 0.0062 15.7 0.4 0.0077 15.4 0.4 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Mt_ATP-synt_B PF05405.14 CDS29666.1 - 0.049 13.2 1.4 0.41 10.3 0.2 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) KNOX2 PF03791.13 CDS29666.1 - 0.07 12.6 0.3 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 KNOX2 domain PIN_2 PF10130.9 CDS29666.1 - 0.18 12.0 2.1 0.26 11.5 2.1 1.4 1 1 0 1 1 1 0 PIN domain PHD PF00628.29 CDS29667.1 - 1.7e-06 27.8 9.1 4.3e-06 26.5 9.1 1.7 1 0 0 1 1 1 1 PHD-finger DUF3498 PF12004.8 CDS29672.2 - 0.15 11.3 0.2 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TOBE_2 PF08402.10 CDS29672.2 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 TOBE domain Ion_trans PF00520.31 CDS29677.2 - 9.1e-255 840.5 110.9 5.7e-61 205.8 6.4 7.1 5 2 2 7 7 7 7 Ion transport protein Ca_chan_IQ PF08763.11 CDS29677.2 - 1.7e-26 92.2 0.1 1.7e-26 92.2 0.1 2.0 2 0 0 2 2 2 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CDS29677.2 - 3.6e-25 87.5 0.1 1e-24 86.0 0.1 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CDS29677.2 - 1.2e-05 24.2 109.4 0.00018 20.4 1.1 12.1 8 5 5 13 13 13 9 Polycystin cation channel 4HBT PF03061.22 CDS29678.2 - 1.5e-12 47.7 0.0 1.9e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CDS29678.2 - 0.00012 22.4 0.1 0.00024 21.5 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Cpn60_TCP1 PF00118.24 CDS29679.2 - 9.5e-159 529.1 1.8 1.1e-158 528.9 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_31 PF01055.26 CDS29680.1 - 6.2e-139 464.0 0.3 7.6e-139 463.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDS29680.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CDS29680.1 - 4.4e-08 32.9 5.5 4.4e-08 32.9 5.5 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CDS29680.1 - 6.8e-08 32.7 1.8 1.1e-06 28.9 0.3 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like DUF1375 PF07119.12 CDS29682.2 - 0.092 13.2 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) Ncstrn_small PF18266.1 CDS29683.2 - 1.1e-34 119.8 0.8 1.7e-34 119.3 0.8 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 CDS29683.2 - 6.2e-17 61.8 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_C12 PF01088.21 CDS29684.2 - 7.4e-54 182.7 0.0 1.2e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDS29684.2 - 2.8e-15 55.9 1.7 4.8e-15 55.2 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med6 PF04934.14 CDS29684.2 - 0.082 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 MED6 mediator sub complex component Ank_2 PF12796.7 CDS29685.2 - 2.5e-23 82.5 0.8 1.4e-09 38.4 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29685.2 - 3.4e-15 56.2 2.4 0.013 16.0 0.1 4.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS29685.2 - 1.6e-14 53.8 2.3 0.0012 19.1 0.0 5.4 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29685.2 - 3.3e-11 42.4 3.1 1.9 9.3 0.1 6.8 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 CDS29685.2 - 7.3e-09 35.7 2.6 0.064 13.7 0.1 5.9 5 1 1 6 6 6 2 Ankyrin repeat MS_channel PF00924.18 CDS29687.2 - 0.018 14.6 0.2 0.025 14.1 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel Coat_F PF07875.12 CDS29687.2 - 0.045 14.0 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Coat F domain Pkinase PF00069.25 CDS29688.2 - 3.2e-10 39.8 0.0 3.8e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29688.2 - 0.0026 17.1 0.0 0.003 16.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.9 CDS29690.1 - 1.3 8.6 11.3 2 8.0 11.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 CDS29693.2 - 4.9e-11 43.1 0.4 8.6e-10 39.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29693.2 - 3.8e-09 36.9 1.7 0.0029 18.2 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29693.2 - 4.1e-07 29.8 0.8 0.73 10.6 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDS29693.2 - 9e-06 25.9 0.4 0.023 15.2 0.1 3.7 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CDS29693.2 - 1.9e-05 24.9 0.5 3.4 8.1 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF2034 PF10356.9 CDS29693.2 - 0.99 8.8 3.1 13 5.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) Rad51 PF08423.11 CDS29699.1 - 7.7e-33 113.8 0.6 1.4e-30 106.5 0.6 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 CDS29699.1 - 0.0095 15.3 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 KaiC RecA PF00154.21 CDS29699.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Abhydrolase_2 PF02230.16 CDS29707.1 - 0.00012 22.0 0.0 0.00013 21.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase zf-CDGSH PF09360.10 CDS29709.1 - 1e-09 38.5 1.3 1e-09 38.5 1.3 1.5 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.9 CDS29709.1 - 2.1e-09 37.3 0.1 3e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus T3SS_LEE_assoc PF13327.6 CDS29714.1 - 0.095 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system subunit RdRP_4 PF02123.16 CDS29715.1 - 0.072 12.0 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Rho_Binding PF08912.11 CDS29715.1 - 0.11 13.3 1.8 0.11 13.3 0.7 1.5 2 0 0 2 2 2 0 Rho Binding DUF2967 PF11179.8 CDS29716.1 - 0.049 11.7 1.2 0.056 11.5 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) GF_recep_IV PF14843.6 CDS29717.2 - 0.0021 17.9 12.9 0.0033 17.2 11.8 1.7 1 1 0 1 1 1 1 Growth factor receptor domain IV VSP PF03302.13 CDS29717.2 - 0.028 13.3 1.8 0.028 13.3 1.8 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein Furin-like PF00757.20 CDS29717.2 - 0.27 11.1 12.5 3 7.7 12.5 2.0 1 1 0 1 1 1 0 Furin-like cysteine rich region Rad51 PF08423.11 CDS29720.2 - 1.6e-49 168.5 0.1 1.9e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 Rad51 AAA_28 PF13521.6 CDS29720.2 - 0.00042 20.6 0.0 0.00051 20.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDS29720.2 - 0.01 15.4 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain GpcrRhopsn4 PF10192.9 CDS29727.1 - 9.1e-26 90.8 7.4 2.3e-14 53.4 3.2 2.3 2 0 0 2 2 2 2 Rhodopsin-like GPCR transmembrane domain SUI1 PF01253.22 CDS29728.1 - 1e-25 90.0 0.7 1.3e-25 89.7 0.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 ScdA_N PF04405.14 CDS29728.1 - 0.02 14.5 0.4 0.046 13.4 0.4 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) FAM177 PF14774.6 CDS29729.1 - 0.0004 20.7 0.0 0.0088 16.4 0.0 2.1 2 0 0 2 2 2 1 FAM177 family DUF4262 PF14081.6 CDS29729.1 - 0.068 13.4 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) Planc_extracel PF07595.12 CDS29730.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Planctomycete extracellular LZ_Tnp_IS481 PF13011.6 CDS29730.1 - 0.066 13.7 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 CDS29730.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-CCCH PF00642.24 CDS29731.1 - 2e-06 27.6 5.7 3.9e-06 26.6 5.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 CDS29731.1 - 3e-06 27.1 0.0 6.6e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CDS29731.1 - 0.00058 19.6 0.0 0.0075 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CDS29731.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 CDS29731.1 - 0.0014 18.6 6.4 0.0027 17.7 6.4 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CDS29731.1 - 0.02 15.6 1.6 0.05 14.3 1.6 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 CDS29731.1 - 0.032 14.0 7.4 0.073 12.9 7.4 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger HLH PF00010.26 CDS29731.1 - 1.6 8.8 8.2 2 8.5 4.6 2.9 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain Spy1 PF11357.8 CDS29732.2 - 1.8e-44 151.2 3.7 2.5e-44 150.7 3.7 1.2 1 0 0 1 1 1 1 Cell cycle regulatory protein C4 PF01413.19 CDS29733.2 - 8e-65 216.2 3.5 5.2e-35 120.2 1.6 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 CDS29733.2 - 2e-15 56.3 53.4 1.6e-08 34.2 22.8 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDS29734.1 - 2.9e-192 622.7 845.1 5.6e-10 38.8 31.5 30.0 7 6 18 25 25 25 23 Collagen triple helix repeat (20 copies) C4 PF01413.19 CDS29734.1 - 1.9e-58 195.6 0.9 1e-30 106.3 0.2 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 CDS29736.1 - 6.9e-201 650.3 865.5 5.2e-10 38.9 28.5 30.8 8 5 18 26 26 26 24 Collagen triple helix repeat (20 copies) C4 PF01413.19 CDS29736.1 - 2.6e-68 227.4 8.4 3e-35 120.9 1.9 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.18 CDS29737.1 - 0.00036 20.2 14.6 0.00052 19.7 14.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Lung_7-TM_R PF06814.13 CDS29738.1 - 2e-60 204.6 16.1 2.7e-60 204.1 16.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CDS29738.1 - 0.0006 19.3 19.1 0.00092 18.7 19.1 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain HELP PF03451.14 CDS29739.1 - 3.5e-29 100.5 0.1 7.4e-29 99.4 0.1 1.6 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 CDS29739.1 - 2e-24 85.4 29.8 0.00028 21.6 0.0 9.3 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS29739.1 - 3.5e-07 30.4 0.2 0.0041 17.4 0.0 5.7 3 2 4 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 CDS29739.1 - 0.0041 16.5 0.0 0.041 13.2 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region WD40_like PF17005.5 CDS29739.1 - 0.039 13.3 0.0 1.5 8.1 0.0 2.9 3 1 0 3 3 3 0 WD40-like domain Coatomer_WDAD PF04053.14 CDS29739.1 - 0.17 10.9 0.0 2.3 7.1 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Lactamase_B_2 PF12706.7 CDS29740.1 - 9.5e-41 139.5 0.2 1.4e-40 139.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UQ_con PF00179.26 CDS29740.1 - 1.3e-27 96.2 0.0 2.1e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lactamase_B_3 PF13483.6 CDS29740.1 - 1.8e-16 60.5 0.0 2.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UEV PF05743.13 CDS29740.1 - 6.5e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CDS29740.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain Lactamase_B PF00753.27 CDS29740.1 - 0.56 10.2 4.9 2.2 8.3 4.9 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 CDS29741.1 - 1.3e-65 221.4 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29741.1 - 3.1e-28 98.8 0.1 4.1e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS29741.1 - 0.00076 19.5 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS29741.1 - 0.002 17.5 0.1 0.0032 16.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDS29741.1 - 0.0066 15.4 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDS29741.1 - 0.011 15.4 0.1 0.023 14.3 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Mre11_DNA_bind PF04152.14 CDS29742.1 - 5e-35 121.3 0.3 8.1e-35 120.6 0.3 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain FYVE PF01363.21 CDS29742.1 - 1.9e-23 82.3 25.5 2e-13 50.3 4.6 3.7 3 1 0 3 3 3 2 FYVE zinc finger Metallophos PF00149.28 CDS29742.1 - 1.5e-13 51.8 0.9 2.3e-13 51.1 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MMR_HSR1 PF01926.23 CDS29742.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2180 PF09947.9 CDS29742.1 - 0.085 12.8 8.4 1.9 8.5 0.7 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) FYVE_2 PF02318.16 CDS29742.1 - 2.7 8.2 19.4 0.89 9.8 2.2 3.7 3 0 0 3 3 3 0 FYVE-type zinc finger zf-met PF12874.7 CDS29743.1 - 5e-19 68.0 24.1 1.4e-06 28.5 1.1 5.5 4 1 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS29743.1 - 4.9e-16 58.5 16.2 2.3e-05 24.6 0.1 4.5 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 CDS29743.1 - 2.4e-07 30.4 13.7 0.019 14.7 0.1 4.4 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_2 PF12756.7 CDS29743.1 - 0.043 14.1 21.4 0.38 11.1 0.1 4.5 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-SCNM1 PF15803.5 CDS29743.1 - 0.056 13.1 14.4 8.1 6.2 0.3 5.1 4 1 0 4 4 4 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_4 PF13894.6 CDS29743.1 - 0.059 14.2 16.2 11 7.2 0.0 6.0 5 0 0 5 5 5 0 C2H2-type zinc finger DUF4187 PF13821.6 CDS29743.1 - 0.15 11.9 1.7 22 4.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) Actin_micro PF17003.5 CDS29743.1 - 0.25 10.5 11.1 1.5 8.0 0.3 3.9 4 0 0 4 4 4 0 Putative actin-like family zf-RING_2 PF13639.6 CDS29744.2 - 8.9e-11 41.9 9.5 1.8e-10 41.0 8.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDS29744.2 - 2.4e-08 33.5 5.9 6e-08 32.3 5.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDS29744.2 - 5.1e-07 29.4 8.6 1.3e-06 28.1 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS29744.2 - 7.2e-07 29.1 5.7 9.1e-07 28.7 4.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDS29744.2 - 2.1e-06 27.9 8.0 2.1e-06 27.9 8.0 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDS29744.2 - 2.4e-06 27.3 5.8 2.4e-06 27.3 5.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS29744.2 - 9.5e-05 22.3 5.7 0.00034 20.6 5.7 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDS29744.2 - 0.00043 20.1 3.7 0.00043 20.1 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS29744.2 - 0.00065 19.5 3.7 0.0019 18.0 3.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PspB PF06667.12 CDS29744.2 - 0.0013 18.8 0.4 0.0026 17.8 0.4 1.5 1 0 0 1 1 1 1 Phage shock protein B zf-ANAPC11 PF12861.7 CDS29744.2 - 0.0022 18.0 2.2 0.0041 17.1 1.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger CrgA PF06781.12 CDS29744.2 - 0.06 13.4 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Cell division protein CrgA RINGv PF12906.7 CDS29744.2 - 1.1 9.4 3.7 2.9 8.1 3.7 1.7 1 0 0 1 1 1 0 RING-variant domain Vault_3 PF17795.1 CDS29745.1 - 6.1e-30 103.0 0.1 1.5e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 Major Vault Protein Repeat domain MVP_shoulder PF11978.8 CDS29745.1 - 2.7e-11 43.5 0.0 4.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_4 PF17796.1 CDS29745.1 - 5.8e-11 42.3 0.3 3e-10 40.0 0.4 2.0 2 0 0 2 2 2 1 Major Vault Protein repeat domain NDUF_B7 PF05676.13 CDS29746.1 - 2.6e-23 81.5 1.5 2.6e-23 81.5 1.5 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CDS29746.1 - 0.064 13.3 2.0 0.11 12.5 2.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Vault PF01505.18 CDS29747.1 - 8.5e-57 189.1 0.0 3.4e-15 55.9 0.0 5.2 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 CDS29747.1 - 1.6e-52 176.6 0.1 2.8e-52 175.7 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CDS29747.1 - 2.2e-35 120.5 0.4 4.5e-29 100.3 0.0 3.5 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 CDS29747.1 - 1.4e-33 115.0 0.3 6.9e-22 77.6 0.1 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CDS29747.1 - 9.7e-33 112.1 0.1 1.9e-31 107.9 0.1 3.0 3 0 0 3 3 3 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CDS29747.1 - 0.00041 20.4 0.0 17 5.6 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3601) DUF2543 PF10820.8 CDS29747.1 - 1.8 8.8 5.3 0.55 10.5 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2543) CAP PF00188.26 CDS29748.1 - 1.2e-20 74.6 6.1 1.8e-20 74.0 6.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDS29749.1 - 3.1e-16 60.3 4.7 3.1e-16 60.3 4.7 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Glycoprotein PF03409.15 CDS29749.1 - 0.002 17.0 0.7 0.002 17.0 0.7 1.2 1 0 0 1 1 1 1 Transmembrane glycoprotein CAP PF00188.26 CDS29750.1 - 4.4e-17 63.1 4.5 8e-17 62.3 4.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aurora-A_bind PF09041.10 CDS29750.1 - 0.061 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Aurora-A binding AXH PF08517.12 CDS29751.1 - 3.3e-28 98.6 0.0 5.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) DUF1582 PF07621.11 CDS29751.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) rve PF00665.26 CDS29753.1 - 0.042 14.0 0.1 3.1 8.0 0.1 2.5 2 1 1 3 3 3 0 Integrase core domain ADIP PF11559.8 CDS29755.1 - 6.8e-08 32.7 5.4 6.8e-08 32.7 5.4 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 CDS29755.1 - 0.0042 16.6 12.1 0.018 14.6 6.5 2.2 2 0 0 2 2 2 2 Golgin subfamily A member 5 EzrA PF06160.12 CDS29755.1 - 0.018 13.2 8.0 0.42 8.7 0.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA RasGAP_C PF03836.15 CDS29755.1 - 0.055 13.6 3.4 0.18 12.0 3.4 1.8 1 0 0 1 1 1 0 RasGAP C-terminus Fmp27_WPPW PF10359.9 CDS29755.1 - 0.14 11.0 7.3 0.11 11.3 3.8 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain BST2 PF16716.5 CDS29755.1 - 0.18 12.4 8.1 0.094 13.3 4.5 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 GAIN_A PF18619.1 CDS29755.1 - 0.47 10.7 5.2 2.8 8.2 0.3 3.9 4 0 0 4 4 4 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Spc7 PF08317.11 CDS29755.1 - 0.57 9.0 10.1 0.12 11.2 4.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDS29755.1 - 2 8.5 6.5 2 8.5 0.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) CAP PF00188.26 CDS29757.2 - 7.9e-20 72.0 3.2 1.2e-19 71.4 3.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4994 PF16385.5 CDS29758.1 - 0.027 14.4 1.2 0.063 13.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function LIM PF00412.22 CDS29759.1 - 3.2e-25 88.1 23.5 1.7e-13 50.6 9.5 2.1 2 0 0 2 2 2 2 LIM domain DUF1610 PF07754.11 CDS29759.1 - 0.0095 15.9 2.8 0.031 14.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1610) CholecysA-Rec_N PF09193.10 CDS29759.1 - 0.052 13.6 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal Herpes_UL55 PF04537.12 CDS29759.1 - 0.68 9.9 6.6 0.39 10.7 4.6 1.6 1 1 0 1 1 1 0 Herpesvirus UL55 protein IQ PF00612.27 CDS29760.1 - 0.093 12.6 0.5 0.29 11.0 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fib_alpha PF08702.10 CDS29760.1 - 0.54 10.4 25.5 0.035 14.3 8.5 3.8 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family OspE PF02471.17 CDS29760.1 - 1.2 9.3 4.1 4.5 7.5 0.0 2.9 3 1 0 3 3 3 0 Borrelia outer surface protein E YabA PF06156.13 CDS29760.1 - 4.8 7.9 21.4 0.063 13.9 3.3 3.2 3 0 0 3 3 3 0 Initiation control protein YabA ApoLp-III PF07464.11 CDS29760.1 - 5.3 7.1 12.5 6 6.9 9.8 2.4 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GAS PF13851.6 CDS29760.1 - 8.3 5.7 33.1 8.6 5.6 0.0 3.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4620 PF15399.6 CDS29761.1 - 0.23 11.8 2.7 0.22 11.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4620) GH131_N PF18271.1 CDS29762.2 - 0.0086 15.8 0.4 0.012 15.3 0.4 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FtsH_ext PF06480.15 CDS29762.2 - 0.13 12.7 3.3 0.34 11.3 1.7 2.4 2 1 0 2 2 2 0 FtsH Extracellular TAF6_C PF07571.13 CDS29763.1 - 1.4e-28 99.0 0.2 4.4e-28 97.4 0.1 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CDS29763.1 - 0.0097 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Sec23_helical PF04815.15 CDS29763.1 - 0.071 12.9 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 Sec23/Sec24 helical domain BORCS8 PF10167.9 CDS29763.1 - 0.17 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 SH3_1 PF00018.28 CDS29764.1 - 2.7e-43 145.3 0.1 4.3e-12 45.4 0.0 4.7 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CDS29764.1 - 4.4e-43 144.9 1.4 6.9e-12 45.0 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain RhoGEF PF00621.20 CDS29764.1 - 1.7e-37 129.4 2.6 1.7e-37 129.4 2.6 2.2 2 0 0 2 2 2 1 RhoGEF domain EF-hand_4 PF12763.7 CDS29764.1 - 9.8e-32 109.0 0.0 1.8e-14 53.5 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 CDS29764.1 - 6.6e-31 105.8 0.4 1.4e-07 31.0 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain PH_13 PF16652.5 CDS29764.1 - 1e-16 61.1 4.5 4.2e-14 52.7 0.0 3.1 3 0 0 3 3 2 2 Pleckstrin homology domain C2 PF00168.30 CDS29764.1 - 2.8e-15 56.5 0.0 9.2e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 CDS29764.1 - 1.7e-09 36.5 0.4 0.0043 16.5 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CDS29764.1 - 6.3e-09 36.2 0.0 0.00039 20.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS29764.1 - 3.3e-05 23.5 0.1 2.2 8.4 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CDS29764.1 - 0.0026 17.2 0.0 0.62 9.7 0.0 2.8 2 0 0 2 2 2 1 EF hand TUDOR PF00567.24 CDS29764.1 - 0.0045 17.0 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Tudor domain PH_16 PF17838.1 CDS29764.1 - 0.035 13.9 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 PH domain PH PF00169.29 CDS29764.1 - 0.064 13.8 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 PH domain EF-hand_8 PF13833.6 CDS29764.1 - 0.15 11.9 0.0 4.3 7.3 0.0 3.0 3 0 0 3 3 2 0 EF-hand domain pair DUF1664 PF07889.12 CDS29764.1 - 0.6 10.2 5.7 0.56 10.3 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SPARC_Ca_bdg PF10591.9 CDS29764.1 - 3.7 7.9 6.2 3.5 8.0 0.0 3.6 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region NPV_P10 PF05531.12 CDS29764.1 - 5.1 7.6 7.6 45 4.6 1.7 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MAT1 PF06391.13 CDS29765.1 - 8.3e-13 48.6 16.7 1.5e-08 34.7 1.5 2.2 1 1 1 2 2 2 2 CDK-activating kinase assembly factor MAT1 Drf_FH1 PF06346.12 CDS29765.1 - 0.0011 18.7 14.3 0.0022 17.7 14.3 1.4 1 0 0 1 1 1 1 Formin Homology Region 1 Kinase-PPPase PF03618.14 CDS29765.1 - 0.067 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase zf-C3HC4_3 PF13920.6 CDS29765.1 - 0.083 12.8 1.5 0.15 12.0 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Met_10 PF02475.16 CDS29766.1 - 1.5e-51 175.0 0.0 2.7e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 CDS29766.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Nuc_sug_transp PF04142.15 CDS29768.1 - 3.1e-120 401.1 16.4 3.8e-120 400.8 16.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CDS29768.1 - 1.3e-07 31.1 19.5 5.6e-07 29.1 19.6 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 CDS29768.1 - 1.6e-07 31.6 32.5 7.1e-06 26.2 4.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family Cytochrom_B561 PF03188.16 CDS29768.1 - 0.002 18.3 2.6 0.002 18.3 2.6 2.8 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 7TMR-DISM_7TM PF07695.11 CDS29768.1 - 0.0087 16.0 12.0 0.0087 16.0 12.0 3.3 2 1 1 3 3 3 1 7TM diverse intracellular signalling ATP19 PF11022.8 CDS29768.1 - 0.01 16.2 3.6 0.019 15.3 0.1 2.9 3 0 0 3 3 3 0 ATP synthase subunit K EmrE PF13536.6 CDS29768.1 - 0.013 15.1 4.5 0.013 15.1 4.5 2.8 3 1 0 3 3 3 0 Putative multidrug resistance efflux transporter DUF202 PF02656.15 CDS29768.1 - 9.4 6.8 17.5 0.57 10.7 2.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF202) Ank_2 PF12796.7 CDS29769.1 - 1.6e-20 73.5 0.2 3.3e-16 59.6 0.4 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS29769.1 - 2.3e-16 58.2 0.8 0.00021 21.5 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CDS29769.1 - 2.4e-15 56.4 0.5 9.3e-06 25.8 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS29769.1 - 1e-14 54.7 0.0 3.7e-10 40.1 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS29769.1 - 4.6e-14 52.1 2.5 0.00028 21.2 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Jak1_Phl PF17887.1 CDS29769.1 - 0.1 12.6 0.4 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Pkinase PF00069.25 CDS29770.1 - 2.5e-50 171.3 0.0 6e-35 120.9 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29770.1 - 1.3e-43 149.1 0.0 1.8e-33 115.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS29770.1 - 0.088 12.1 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CDS29770.1 - 0.21 11.5 0.9 60 3.4 0.2 3.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family PAP_assoc PF03828.19 CDS29771.1 - 4e-11 42.9 0.0 1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDS29771.1 - 4.2e-09 36.6 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDS29771.1 - 0.0028 17.7 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PNP_UDP_1 PF01048.20 CDS29773.1 - 1.7e-38 132.2 0.0 2e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RL10P_insert PF17777.1 CDS29774.1 - 1.8e-21 75.9 0.4 3.1e-21 75.1 0.4 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDS29774.1 - 1.4e-17 63.6 0.3 8.2e-17 61.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CDS29774.1 - 2.1e-15 57.1 3.0 3.8e-15 56.2 3.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 CDS29774.1 - 0.012 15.4 3.3 4.8 6.9 0.0 3.8 4 0 0 4 4 4 0 Pox virus Ag35 surface protein PLAT PF01477.23 CDS29775.1 - 2.2e-06 28.2 0.0 4.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Prion_bPrPp PF11587.8 CDS29775.1 - 6.2 6.7 7.3 0.36 10.7 0.9 2.2 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DENN PF02141.21 CDS29776.1 - 8.1e-44 149.8 0.1 1.5e-43 148.9 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CDS29776.1 - 1.7e-15 57.5 0.5 3.6e-15 56.5 0.5 1.6 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 CDS29776.1 - 0.16 11.9 0.3 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis Ribosomal_S13_N PF08069.12 CDS29777.1 - 2.4e-29 101.1 0.4 4.3e-29 100.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CDS29777.1 - 5.8e-14 52.1 1.1 1.1e-13 51.2 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 IBR PF01485.21 CDS29778.1 - 9.2e-20 70.6 37.7 9.5e-14 51.4 2.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CDS29778.1 - 3.8e-08 33.5 6.7 3.8e-08 33.5 6.7 4.5 3 2 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 CDS29778.1 - 3.3e-06 26.9 7.9 3.3e-06 26.9 7.9 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS29778.1 - 3.6e-06 26.9 4.6 3.6e-06 26.9 4.6 4.3 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS29778.1 - 3.1e-05 23.7 8.0 3.1e-05 23.7 8.0 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS29778.1 - 0.00024 20.9 6.8 0.00024 20.9 6.8 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 CDS29778.1 - 0.00038 20.7 0.1 0.0018 18.6 0.0 2.1 2 1 0 2 2 2 1 RWD domain zf-RING_11 PF17123.5 CDS29778.1 - 0.00039 20.1 8.4 0.00039 20.1 8.4 3.0 3 0 0 3 3 3 1 RING-like zinc finger FYVE PF01363.21 CDS29778.1 - 0.0022 18.1 4.7 0.0022 18.1 4.7 3.5 3 0 0 3 3 3 1 FYVE zinc finger Prok-RING_4 PF14447.6 CDS29778.1 - 0.0033 17.2 7.6 0.0033 17.2 7.6 4.6 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 SNAP PF14938.6 CDS29779.1 - 5.1e-93 311.6 16.1 5.8e-93 311.4 16.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CDS29779.1 - 4.2e-10 39.8 13.8 2.3e-06 27.8 1.2 2.8 2 1 2 4 4 3 3 Tetratricopeptide repeat NSF PF02071.20 CDS29779.1 - 4.2e-06 26.5 28.8 0.19 12.6 1.0 8.3 7 0 0 7 7 7 3 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.6 CDS29779.1 - 0.00085 19.2 1.5 19 5.6 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS29779.1 - 0.003 18.2 7.2 4.5 8.3 0.0 6.0 4 1 5 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS29779.1 - 0.049 13.7 19.5 9.7 6.6 0.2 7.0 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS29779.1 - 0.14 12.9 12.7 26 5.8 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat MSG PF02349.15 CDS29779.1 - 0.31 11.3 2.6 0.37 11.0 0.9 2.0 2 0 0 2 2 2 0 Major surface glycoprotein TPR_10 PF13374.6 CDS29779.1 - 1.2 9.1 4.2 16 5.5 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CDS29779.1 - 1.6 9.5 15.2 24 5.8 0.1 5.3 6 0 0 6 6 5 0 Sel1 repeat Spatacsin_C PF14649.6 CDS29779.1 - 2.3 7.2 9.0 9 5.3 5.9 2.5 2 1 0 2 2 2 0 Spatacsin C-terminus MIT PF04212.18 CDS29779.1 - 2.9 8.0 13.4 12 6.1 0.0 5.4 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain PBP_sp32 PF07222.12 CDS29780.1 - 0.003 17.1 4.8 0.0036 16.8 4.8 1.3 1 0 0 1 1 1 1 Proacrosin binding protein sp32 Asp-B-Hydro_N PF05279.11 CDS29780.1 - 0.025 14.6 12.4 0.029 14.5 12.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CDS29780.1 - 2.7 6.7 10.7 3.3 6.4 10.7 1.1 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 CDS29782.2 - 0.0049 16.4 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX6B PF02297.17 CDS29785.1 - 3.8e-16 59.1 1.5 4.8e-16 58.8 1.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX6B PF02297.17 CDS29786.1 - 1.2e-15 57.5 0.6 1.2e-15 57.5 0.6 1.3 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb MMR_HSR1_Xtn PF16897.5 CDS29787.1 - 1.4e-45 153.6 0.5 2.7e-45 152.8 0.5 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDS29787.1 - 1.2e-23 82.9 0.1 2.3e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDS29787.1 - 1.6e-19 70.0 0.0 4.4e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS29787.1 - 6.9e-11 41.9 0.1 1.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS29787.1 - 0.0017 18.4 0.2 1.4 9.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 CDS29787.1 - 0.0076 15.8 0.2 3.8 7.0 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CDS29787.1 - 0.017 14.1 0.2 0.046 12.7 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB EzrA PF06160.12 CDS29790.1 - 0.0014 16.9 5.3 0.0014 16.9 5.3 5.2 3 1 2 5 5 5 3 Septation ring formation regulator, EzrA Nup54 PF13874.6 CDS29790.1 - 0.0063 16.6 2.1 0.0063 16.6 2.1 6.2 2 1 1 4 4 4 1 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 CDS29790.1 - 0.031 14.3 22.1 0.12 12.4 1.6 4.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 CDS29790.1 - 1.2 9.1 49.7 0.15 12.1 5.9 6.2 3 3 3 6 6 6 0 Laminin Domain II Bromodomain PF00439.25 CDS29791.1 - 8.2e-12 45.0 0.4 9.4e-11 41.6 0.1 2.4 2 0 0 2 2 2 1 Bromodomain DUF5027 PF16430.5 CDS29791.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) KLRAQ PF10205.9 CDS29791.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.5 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein La PF05383.17 CDS29792.1 - 2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 La domain fn3 PF00041.21 CDS29793.2 - 1.5e-26 92.6 0.9 2.5e-08 34.1 0.1 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDS29793.2 - 1.6e-06 28.6 5.5 0.19 12.3 0.1 4.3 3 1 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 CDS29793.2 - 7.4e-05 22.8 0.3 1.3 9.2 0.0 4.0 4 0 0 4 4 4 2 Fibronectin type III domain DUF2645 PF10840.8 CDS29793.2 - 0.073 13.7 3.0 0.33 11.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) DUF3295 PF11702.8 CDS29793.2 - 0.19 11.0 0.4 0.31 10.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Big_5 PF13205.6 CDS29793.2 - 0.46 11.2 3.0 18 6.1 0.1 3.3 3 0 0 3 3 3 0 Bacterial Ig-like domain La PF05383.17 CDS29798.2 - 2.1e-08 34.1 0.0 4.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 La domain CH PF00307.31 CDS29799.2 - 8.5e-48 161.1 6.2 1e-21 77.2 0.0 5.8 5 0 0 5 5 5 3 Calponin homology (CH) domain DUF4586 PF15239.6 CDS29799.2 - 1.1e-44 153.9 12.7 3e-44 152.4 12.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) CAMSAP_CH PF11971.8 CDS29799.2 - 2.2e-09 37.0 1.1 0.0021 17.8 0.0 4.9 5 0 0 5 5 5 2 CAMSAP CH domain Mac PF12464.8 CDS29799.2 - 0.11 12.7 0.3 1.3 9.3 0.3 3.0 1 0 0 1 1 1 0 Maltose acetyltransferase Erf4 PF10256.9 CDS29799.2 - 0.29 11.2 8.9 49 4.1 0.0 6.6 5 1 0 5 5 5 0 Golgin subfamily A member 7/ERF4 family Aurora-A_bind PF09041.10 CDS29799.2 - 4.7 7.3 7.8 14 5.8 0.0 4.5 4 0 0 4 4 4 0 Aurora-A binding DUF1192 PF06698.11 CDS29799.2 - 5.6 7.1 7.2 16 5.6 0.6 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) SKA1 PF07160.12 CDS29800.1 - 0.0012 18.8 1.4 0.0019 18.1 1.4 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Fib_alpha PF08702.10 CDS29800.1 - 0.0079 16.4 10.3 0.0097 16.1 8.5 1.9 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 CDS29800.1 - 0.0083 16.1 14.1 0.031 14.3 0.4 2.8 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 CDS29800.1 - 0.0095 15.6 15.1 0.04 13.6 15.1 1.9 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 CDS29800.1 - 0.013 14.2 7.4 0.018 13.7 7.4 1.1 1 0 0 1 1 1 0 AAA domain PolyA_pol PF01743.20 CDS29800.1 - 0.032 14.6 1.2 0.059 13.8 1.2 1.4 1 0 0 1 1 1 0 Poly A polymerase head domain Exonuc_VII_L PF02601.15 CDS29800.1 - 0.058 13.0 6.8 0.076 12.6 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GNAT_acetyltran PF12746.7 CDS29800.1 - 0.06 12.9 0.4 0.097 12.2 0.4 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase DUF4407 PF14362.6 CDS29800.1 - 0.063 12.6 7.1 0.087 12.2 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 CDS29800.1 - 0.087 12.6 6.2 0.14 11.9 0.5 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain WASH-7_N PF14745.6 CDS29800.1 - 0.12 10.8 3.7 0.16 10.5 3.7 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal V_ATPase_I PF01496.19 CDS29800.1 - 0.16 9.9 6.1 0.18 9.7 6.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 CDS29800.1 - 0.25 12.0 10.6 2.8 8.6 1.4 2.7 2 1 0 2 2 2 0 SlyX MPS2 PF17060.5 CDS29800.1 - 0.26 10.5 4.9 0.39 9.9 4.9 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 ATG16 PF08614.11 CDS29800.1 - 0.27 11.4 15.4 0.29 11.3 13.2 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Glutaredoxin2_C PF04399.13 CDS29800.1 - 0.32 10.8 3.5 1.6 8.6 0.3 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Prominin PF05478.11 CDS29800.1 - 0.35 8.8 4.0 0.43 8.5 4.0 1.1 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 CDS29800.1 - 0.52 10.8 3.7 58 4.2 3.3 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 CDS29800.1 - 0.55 10.0 8.6 0.17 11.7 1.0 2.1 2 0 0 2 2 2 0 USP8 interacting DUF16 PF01519.16 CDS29800.1 - 0.85 10.1 9.6 1.5 9.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 CDS29800.1 - 0.91 9.5 15.3 2.3 8.2 7.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 CDS29800.1 - 1.1 9.1 16.0 0.17 11.7 1.8 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 CDS29800.1 - 1.4 7.7 13.5 2.1 7.1 13.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 CDS29800.1 - 1.8 8.5 10.9 0.43 10.5 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4061 PF13270.6 CDS29800.1 - 2.9 8.3 7.6 0.85 10.0 1.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) Macoilin PF09726.9 CDS29800.1 - 3 6.3 10.3 4.1 5.9 10.3 1.2 1 0 0 1 1 1 0 Macoilin family CorA PF01544.18 CDS29800.1 - 3.1 7.0 8.2 8.2 5.6 8.2 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2721 PF11026.8 CDS29800.1 - 3.6 7.5 4.5 4.6 7.1 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF4200 PF13863.6 CDS29800.1 - 4.7 7.7 16.7 12 6.3 16.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4349 PF14257.6 CDS29800.1 - 5.2 6.5 8.3 2.1 7.8 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2203 PF09969.9 CDS29800.1 - 5.8 7.7 8.3 7.6 7.3 4.6 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 CDS29800.1 - 7.4 5.7 8.1 31 3.7 8.1 1.8 1 1 0 1 1 1 0 TMPIT-like protein zf-CpG_bind_C PF12269.8 CDS29800.1 - 8.1 6.2 10.3 2.1 8.1 3.1 2.1 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain CENP-H PF05837.12 CDS29800.1 - 8.2 6.9 12.6 9.3 6.7 10.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) C2 PF00168.30 CDS29801.1 - 8.4e-14 51.7 0.0 7.5e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDS29801.1 - 0.0008 19.0 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Transposase_1 PF01359.18 CDS29802.1 - 1.1e-10 41.2 1.2 1.8e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) RNA_pol_Rpb5_C PF01191.19 CDS29804.2 - 5.3e-31 106.3 0.2 8.9e-31 105.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDS29804.2 - 1.3e-13 51.3 0.1 2.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Cytidylate_kin2 PF13189.6 CDS29804.2 - 0.053 13.6 0.1 0.099 12.8 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase-like family AKAP7_NLS PF10469.9 CDS29805.1 - 4.3e-35 121.5 0.0 5.9e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CDS29805.1 - 3.8e-07 30.1 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily KH_1 PF00013.29 CDS29805.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 KH domain LigT_PEase PF02834.16 CDS29805.1 - 0.0071 16.5 0.4 0.67 10.2 0.2 2.8 2 1 0 2 2 2 1 LigT like Phosphoesterase TED_complement PF07678.14 CDS29806.2 - 7.7e-59 199.3 0.4 1.2e-58 198.6 0.4 1.2 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 CDS29806.2 - 3e-15 56.7 0.0 9e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain A2M PF00207.22 CDS29806.2 - 2.3e-14 53.0 0.1 1.7e-11 43.8 0.0 3.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin family MG3 PF17791.1 CDS29806.2 - 3.3e-12 46.5 0.0 1e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 Macroglobulin domain MG3 MG2 PF01835.19 CDS29806.2 - 8.8e-09 35.7 0.1 9e-07 29.3 0.1 3.2 2 1 0 2 2 2 1 MG2 domain DSL PF01414.19 CDS29806.2 - 8.8e-05 22.7 3.1 8.8e-05 22.7 3.1 2.9 2 0 0 2 2 2 1 Delta serrate ligand EGF_2 PF07974.13 CDS29806.2 - 0.0012 19.2 10.0 0.0012 19.2 10.0 4.4 4 0 0 4 4 4 1 EGF-like domain NPCBM_assoc PF10633.9 CDS29806.2 - 0.013 15.7 0.1 6.1 7.2 0.0 3.3 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase zf-HIT PF04438.16 CDS29808.1 - 2.5e-06 27.2 6.4 3.8e-06 26.7 6.4 1.3 1 0 0 1 1 1 1 HIT zinc finger PAPA-1 PF04795.12 CDS29808.1 - 3.1 8.7 11.9 0.082 13.7 2.4 2.7 2 2 0 2 2 2 0 PAPA-1-like conserved region RhoGAP PF00620.27 CDS29809.1 - 1.3e-29 103.0 0.1 3.4e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 CDS29809.1 - 4.3e-07 29.7 7.4 9.8e-07 28.6 7.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CDS29809.1 - 0.0013 19.0 5.5 0.0014 18.9 3.7 2.1 2 0 0 2 2 2 1 C1 domain FYVE PF01363.21 CDS29809.1 - 0.012 15.7 1.1 0.033 14.3 1.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger DUF1664 PF07889.12 CDS29809.1 - 0.016 15.2 2.4 0.028 14.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Zf_RING PF16744.5 CDS29809.1 - 0.093 12.9 6.3 0.27 11.4 6.3 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger YabA PF06156.13 CDS29809.1 - 0.49 11.1 4.7 0.96 10.1 4.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Rx_N PF18052.1 CDS29809.1 - 0.56 10.5 2.8 2.5 8.4 2.6 2.2 2 1 1 3 3 3 0 Rx N-terminal domain PHD PF00628.29 CDS29809.1 - 3.1 7.8 6.7 6.7 6.7 6.7 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CDS29809.1 - 4 7.4 6.3 9.8 6.2 6.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 MIF4G_like PF09088.11 CDS29810.2 - 2e-28 99.5 2.8 2.9e-28 99.0 1.6 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 CDS29810.2 - 4.4e-28 98.5 0.1 8.6e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CDS29810.2 - 1.3e-08 34.8 0.8 2.4e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain Hexapep PF00132.24 CDS29811.1 - 2.2e-07 30.3 4.8 0.00045 19.8 3.8 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CDS29811.1 - 6.6e-05 21.2 0.4 0.0001 20.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 CDS29811.1 - 8.3e-05 22.3 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 CDS29811.1 - 0.068 12.1 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 L-fucokinase DAGK_acc PF00609.19 CDS29811.1 - 0.069 13.5 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase accessory domain zf-C4 PF00105.18 CDS29812.1 - 1.1e-25 89.9 13.2 1.1e-25 89.9 13.2 2.5 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS29812.1 - 3.9e-08 33.1 0.4 7.6e-08 32.2 0.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Lig_chan PF00060.26 CDS29813.2 - 3.2e-28 98.5 0.4 6.1e-28 97.5 0.4 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CDS29813.2 - 2.6e-23 82.4 0.0 4.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CDS29813.2 - 2.2e-20 73.0 0.0 5.8e-20 71.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 7TM_GPCR_Str PF10326.9 CDS29813.2 - 0.027 13.9 0.2 0.052 12.9 0.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str SlyX PF04102.12 CDS29813.2 - 0.26 11.9 0.5 1.2 9.8 0.4 2.0 2 0 0 2 2 2 0 SlyX TFIIS_M PF07500.14 CDS29814.1 - 3.2e-29 101.7 0.2 5.1e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CDS29814.1 - 3.8e-18 65.1 6.4 7.2e-18 64.2 6.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CDS29814.1 - 1.5e-11 44.1 4.4 1.9e-11 43.8 2.1 2.4 3 0 0 3 3 3 1 TFIIS helical bundle-like domain FHA PF00498.26 CDS29814.1 - 2.7e-10 40.4 0.8 6e-10 39.3 0.8 1.6 1 0 0 1 1 1 1 FHA domain Baculo_LEF5_C PF11792.8 CDS29814.1 - 0.32 10.7 1.8 0.9 9.3 1.8 1.8 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Neur_chan_LBD PF02931.23 CDS29815.1 - 1.3e-46 158.8 1.7 1.7e-46 158.4 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS29815.1 - 4.1e-25 89.2 1.5 1.9e-21 77.2 0.3 2.3 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RICTOR_N PF14664.6 CDS29816.2 - 2.7e-17 62.8 0.0 2.1e-05 23.7 0.1 3.5 3 1 0 3 3 3 3 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 CDS29816.2 - 7.2e-10 39.0 0.7 5.9e-09 36.1 0.3 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 CDS29816.2 - 1.8e-06 27.7 0.5 8.4e-06 25.5 0.2 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CDS29816.2 - 2e-06 28.2 4.1 6.6e-06 26.5 2.0 2.9 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.6 CDS29816.2 - 0.14 12.5 0.1 7.1 7.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats P4Ha_N PF08336.11 CDS29817.1 - 1.4e-24 86.7 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CDS29817.1 - 1.8e-15 57.6 0.1 3e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CDS29817.1 - 6e-07 29.1 0.3 0.033 14.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 CDS29817.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_8 PF13181.6 CDS29817.1 - 0.0075 16.4 0.5 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS29817.1 - 0.0089 16.3 0.2 1.9 8.8 0.0 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS29817.1 - 0.0096 15.7 0.2 0.53 10.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS29817.1 - 0.021 15.0 0.0 11 6.4 0.0 2.4 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDS29817.1 - 0.12 12.3 0.1 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS29817.1 - 0.17 12.0 0.1 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS29817.1 - 2.1 8.5 3.8 1.4 9.1 0.1 2.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Pkinase_Tyr PF07714.17 CDS29818.1 - 4.7e-56 190.0 0.0 6.3e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS29818.1 - 1.7e-29 103.0 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS29818.1 - 2.3e-11 43.6 0.0 5.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CDS29818.1 - 0.00047 20.0 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS29818.1 - 0.00092 18.8 0.0 0.0024 17.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Pkinase PF00069.25 CDS29820.1 - 1e-46 159.4 0.0 2e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29820.1 - 1.8e-22 79.9 0.0 3.4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CDS29820.1 - 0.0022 17.1 0.1 0.0036 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase SAM_Ste50p PF09235.10 CDS29820.1 - 0.068 13.4 1.4 0.12 12.6 0.2 2.0 2 0 0 2 2 2 0 Ste50p, sterile alpha motif SPAN-X PF07458.12 CDS29820.1 - 1.5 9.3 14.9 2.6 8.5 8.7 2.4 2 0 0 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome SelP_N PF04592.14 CDS29820.1 - 4.9 6.5 22.4 9.5 5.5 22.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Inositol_P PF00459.25 CDS29822.1 - 3.7e-47 161.1 0.0 4.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Branch PF02485.21 CDS29823.1 - 7.8e-28 97.6 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme WSC PF01822.19 CDS29823.1 - 5e-11 42.6 0.2 1.1e-10 41.5 0.2 1.6 1 0 0 1 1 1 1 WSC domain Xylo_C PF12529.8 CDS29823.1 - 0.00023 20.8 0.0 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Xylosyltransferase C terminal Pkinase PF00069.25 CDS29824.1 - 1.9e-73 247.1 0.0 2.2e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29824.1 - 7.6e-35 120.4 0.0 9.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29824.1 - 5.4e-10 39.1 0.0 7.7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDS29824.1 - 3.6e-05 22.9 0.3 4.7e-05 22.5 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Peptidase_C3 PF00548.20 CDS29824.1 - 0.087 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) DUF2333 PF10095.9 CDS29825.1 - 0.093 11.7 0.0 0.093 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) APC1_C PF18122.1 CDS29825.1 - 0.16 11.9 0.1 0.17 11.8 0.1 1.0 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain RPEL PF02755.15 CDS29827.1 - 2.4e-20 71.5 7.1 1.9e-07 30.5 0.9 3.8 3 0 0 3 3 3 3 RPEL repeat PTPLA PF04387.14 CDS29828.1 - 3.1e-51 173.4 9.7 3.5e-51 173.2 9.7 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pro_isomerase PF00160.21 CDS29829.1 - 5.2e-51 173.0 0.0 3.3e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDS29829.1 - 4e-20 71.4 0.0 7.1e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 CDS29829.1 - 0.00043 20.3 0.0 0.0008 19.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4944) DUF2594 PF10769.9 CDS29829.1 - 0.015 15.3 0.1 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) RRM_7 PF16367.5 CDS29829.1 - 0.044 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 CDS29829.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif LSDAT_euk PF18139.1 CDS29831.2 - 2.5e-43 148.4 0.0 3.5e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 SLOG in TRPM Ank_4 PF13637.6 CDS29831.2 - 6.6e-19 68.0 2.6 2.2e-11 44.0 0.6 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS29831.2 - 5.6e-16 58.9 0.3 9.6e-14 51.7 0.3 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) LSDAT_prok PF18171.1 CDS29831.2 - 2.9e-14 52.8 0.0 9.1e-14 51.2 0.0 1.7 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote Ank_5 PF13857.6 CDS29831.2 - 2.5e-13 49.9 2.1 5.5e-08 32.9 0.9 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29831.2 - 9.9e-13 47.0 2.3 0.00015 21.9 0.6 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDS29831.2 - 2.7e-12 46.5 6.9 0.00089 19.6 1.7 4.2 4 0 0 4 4 4 3 Ankyrin repeat LSDAT_euk PF18139.1 CDS29833.2 - 1.7e-50 171.9 0.0 2.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CDS29833.2 - 1.1e-11 44.4 0.0 3e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote DUF5053 PF16476.5 CDS29833.2 - 0.062 13.0 0.2 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Arch_fla_DE PF04659.13 CDS29833.2 - 0.09 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal flagella protein Ribonuclease_3 PF00636.26 CDS29834.2 - 2.8e-51 172.6 0.0 3.1e-31 108.1 0.0 3.3 2 0 0 2 2 2 2 Ribonuclease III domain PAZ PF02170.22 CDS29834.2 - 3.7e-25 88.3 0.0 8.5e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 PAZ domain Ribonucleas_3_3 PF14622.6 CDS29834.2 - 1.6e-14 54.2 0.0 6.4e-05 23.1 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 CDS29834.2 - 4.4e-10 39.6 0.0 1.5e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain RBD PF02196.15 CDS29834.2 - 0.017 15.2 0.0 14 5.9 0.0 2.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain RT_RNaseH PF17917.1 CDS29835.1 - 0.0032 17.7 0.6 0.0091 16.3 0.3 2.0 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF4019 PF13211.6 CDS29836.1 - 0.068 13.6 0.1 0.08 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) zf-RING_2 PF13639.6 CDS29837.1 - 2.9e-10 40.3 8.9 7.1e-10 39.1 5.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDS29837.1 - 3.8e-06 26.5 5.6 6.7e-06 25.7 5.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDS29837.1 - 0.00044 20.2 5.8 0.00044 20.2 5.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDS29837.1 - 0.00051 20.3 6.4 0.00051 20.3 6.4 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDS29837.1 - 0.00054 19.7 5.8 0.00054 19.7 5.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PRP21_like_P PF12230.8 CDS29837.1 - 0.0017 18.2 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein FANCL_C PF11793.8 CDS29837.1 - 0.011 15.9 6.9 0.12 12.5 3.6 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CDS29837.1 - 0.022 14.6 6.6 0.28 11.1 3.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS29837.1 - 0.026 14.4 5.7 0.026 14.4 5.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS29837.1 - 0.028 14.4 7.5 0.077 13.0 4.4 2.3 2 0 0 2 2 2 0 zinc-RING finger domain RNF220 PF15926.5 CDS29837.1 - 0.043 13.4 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Zn_ribbon_17 PF17120.5 CDS29837.1 - 0.045 13.4 4.9 0.042 13.5 3.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDS29837.1 - 0.11 12.6 8.8 2.6 8.2 0.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDS29837.1 - 0.48 10.6 6.2 1.2 9.3 6.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CDS29837.1 - 1.1 9.7 8.1 0.29 11.5 4.3 2.0 2 0 0 2 2 2 0 RING-like domain MPC PF03650.13 CDS29838.1 - 2.8e-37 127.2 0.1 3.7e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF5389 PF17364.2 CDS29838.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5389) RVT_1 PF00078.27 CDS29839.1 - 1e-06 28.5 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.23 CDS29841.1 - 4.5e-57 193.4 0.0 1.3e-56 191.9 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF3535 PF12054.8 CDS29841.1 - 1.9e-26 93.3 2.3 2.7e-22 79.6 0.1 4.9 4 1 0 4 4 4 2 Domain of unknown function (DUF3535) Helicase_C PF00271.31 CDS29841.1 - 3.5e-17 62.7 0.0 9.7e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 CDS29841.1 - 0.00043 20.6 1.8 0.004 17.5 0.1 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CDS29841.1 - 0.00051 20.1 12.3 11 6.7 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat DUF3385 PF11865.8 CDS29841.1 - 0.01 15.8 0.2 0.04 13.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Enkurin PF13864.6 CDS29843.2 - 8.4e-19 67.8 1.1 8.4e-19 67.8 1.1 1.8 2 0 0 2 2 2 1 Calmodulin-binding ADH_zinc_N_2 PF13602.6 CDS29844.2 - 6.7e-09 36.9 0.0 6.4e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDS29844.2 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDS29844.2 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase I-set PF07679.16 CDS29845.2 - 4.3e-11 42.7 0.0 7.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS29845.2 - 1e-10 42.1 0.0 2.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS29845.2 - 4.6e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDS29845.2 - 0.0043 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain EGF PF00008.27 CDS29845.2 - 0.0079 16.5 4.9 0.0079 16.5 4.9 1.9 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 CDS29845.2 - 0.053 13.7 3.5 0.16 12.2 3.5 1.8 1 0 0 1 1 1 0 Laminin EGF domain EGF_3 PF12947.7 CDS29845.2 - 0.11 12.7 3.4 0.31 11.3 3.4 1.7 1 0 0 1 1 1 0 EGF domain PAP2_3 PF14378.6 CDS29845.2 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily EGF_2 PF07974.13 CDS29845.2 - 5.8 7.4 8.6 14 6.1 8.6 1.7 1 0 0 1 1 1 0 EGF-like domain Solute_trans_a PF03619.16 CDS29846.2 - 2.9e-86 289.3 28.5 3.6e-86 289.0 28.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-RING_2 PF13639.6 CDS29846.2 - 3.3e-11 43.3 5.0 3.3e-11 43.3 5.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS29846.2 - 2.1e-10 40.4 6.2 6.5e-10 38.9 6.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS29846.2 - 1.1e-09 38.0 6.6 1.1e-09 38.0 6.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS29846.2 - 1.8e-09 37.3 6.5 1.8e-09 37.3 6.5 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS29846.2 - 3.8e-08 33.0 2.5 3.8e-08 33.0 2.5 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS29846.2 - 9.2e-07 28.7 4.7 9.2e-07 28.7 4.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CDS29846.2 - 4e-06 27.0 6.1 4e-06 27.0 6.1 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDS29846.2 - 4.8e-05 23.1 3.2 4.8e-05 23.1 3.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDS29846.2 - 0.0007 19.6 1.6 0.0021 18.1 1.6 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDS29846.2 - 0.001 18.8 6.6 0.001 18.8 6.6 2.2 3 0 0 3 3 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CDS29846.2 - 0.0012 19.0 5.4 0.0012 19.0 5.4 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CDS29846.2 - 0.0025 17.4 3.0 0.0056 16.3 3.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CDS29846.2 - 0.022 14.6 1.2 0.022 14.6 1.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 CDS29846.2 - 0.087 12.7 2.1 0.18 11.6 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CDS29846.2 - 0.3 11.2 2.4 0.75 10.0 2.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CDS29846.2 - 5.3 7.3 8.0 19 5.6 8.0 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 CDS29847.1 - 2.8e-27 95.7 0.0 4.3e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29847.1 - 1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS29847.1 - 7.5e-08 31.5 0.1 7.5e-08 31.5 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDS29847.1 - 0.0002 21.4 0.6 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDS29847.1 - 0.025 14.0 0.1 0.025 14.0 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CDS29847.1 - 0.027 13.5 0.1 0.053 12.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1102 PF06510.11 CDS29847.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) FliC PF12445.8 CDS29847.1 - 0.77 10.1 4.0 0.23 11.8 0.3 1.9 2 0 0 2 2 2 0 Flagellin protein Myotub-related PF06602.14 CDS29848.2 - 6.6e-108 360.8 0.0 1e-59 202.2 0.0 2.3 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain DUF1403 PF07183.11 CDS29848.2 - 0.0072 15.9 0.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1403) DcrB PF08786.11 CDS29848.2 - 0.021 14.9 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 DcrB Symplekin_C PF12295.8 CDS29848.2 - 0.034 14.3 0.1 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal hSac2 PF12456.8 CDS29848.2 - 0.078 12.7 0.3 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Inositol phosphatase Nucleoporin_FG2 PF15967.5 CDS29848.2 - 5.6 5.4 8.6 9.8 4.6 1.2 2.2 2 0 0 2 2 2 0 Nucleoporin FG repeated region MPC PF03650.13 CDS29849.1 - 2.4e-42 143.6 0.5 2.9e-42 143.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 CDS29849.1 - 0.013 15.5 0.4 0.019 15.0 0.4 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange UPF0242 PF06785.11 CDS29849.1 - 0.21 11.7 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 CDS29850.1 - 0.063 13.8 1.0 13 6.3 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LSM PF01423.22 CDS29851.1 - 1.8e-20 72.4 0.2 2.4e-20 72.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M16_M PF16187.5 CDS29851.1 - 0.19 11.0 0.1 0.33 10.2 0.1 1.3 1 1 0 1 1 1 0 Middle or third domain of peptidase_M16 PRIMA1 PF16101.5 CDS29854.1 - 2 8.4 8.1 5.6 7.0 2.9 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 K-box PF01486.17 CDS29855.2 - 0.56 10.4 4.0 0.58 10.4 0.3 2.6 3 1 0 3 3 3 0 K-box region Noggin PF05806.12 CDS29856.2 - 1.5e-24 87.1 4.4 1.3e-22 80.8 0.2 2.2 2 0 0 2 2 2 2 Noggin Folate_carrier PF01770.18 CDS29856.2 - 0.096 11.4 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier ARS2 PF04959.13 CDS29857.2 - 2.2e-27 96.7 0.1 6.7e-27 95.1 0.1 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 CDS29857.2 - 1.2e-19 70.5 0.5 3.3e-19 69.1 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) Macoilin PF09726.9 CDS29857.2 - 0.0084 14.7 19.6 0.014 14.0 19.6 1.3 1 0 0 1 1 1 1 Macoilin family Presenilin PF01080.17 CDS29857.2 - 0.53 9.0 11.7 0.85 8.3 11.7 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CDS29857.2 - 0.92 8.3 26.4 1.5 7.6 26.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CDS29857.2 - 0.93 7.8 13.5 1.5 7.1 13.5 1.2 1 0 0 1 1 1 0 Menin SPX PF03105.19 CDS29857.2 - 1.1 9.1 27.0 2.7 7.8 27.0 1.6 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CDS29857.2 - 2.3 6.8 15.0 3.5 6.2 15.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM199X PF15814.5 CDS29857.2 - 3.3 6.7 27.9 7 5.6 27.9 1.5 1 0 0 1 1 1 0 Protein family FAM199X Miga PF10265.9 CDS29857.2 - 3.4 6.5 20.4 5.5 5.8 20.4 1.2 1 0 0 1 1 1 0 Mitoguardin Tmemb_cc2 PF10267.9 CDS29857.2 - 4.8 6.2 17.9 11 5.1 17.9 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RAP1 PF07218.11 CDS29857.2 - 5 5.3 25.1 8 4.6 25.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 CDS29858.2 - 5e-70 235.9 0.1 9.7e-70 234.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29858.2 - 5.9e-31 107.7 0.0 8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS29858.2 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CDS29858.2 - 0.059 12.4 0.1 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 zf-C4 PF00105.18 CDS29859.2 - 7.8e-30 103.2 17.8 1.5e-29 102.2 17.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS29859.2 - 1.6e-21 76.8 0.0 3.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor EnY2 PF10163.9 CDS29860.1 - 3.4e-21 75.4 0.4 4.5e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 PC_rep PF01851.22 CDS29860.1 - 0.0034 17.7 0.6 6.1 7.5 0.0 3.1 2 1 1 3 3 3 1 Proteasome/cyclosome repeat DUF445 PF04286.12 CDS29860.1 - 0.0039 17.1 1.3 0.0046 16.8 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) UPF0184 PF03670.13 CDS29860.1 - 0.0065 16.8 0.2 0.0065 16.8 0.2 2.0 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0184) YqbF PF14553.6 CDS29860.1 - 0.048 13.5 0.1 8.8 6.3 0.0 2.4 2 0 0 2 2 2 0 YqbF, hypothetical protein domain Mnd1 PF03962.15 CDS29860.1 - 0.13 12.6 1.1 3.7 7.9 0.0 2.8 1 1 2 3 3 3 0 Mnd1 HTH domain CAF1C_H4-bd PF12265.8 CDS29861.1 - 2.2e-28 98.3 1.7 9.2e-28 96.3 0.3 2.7 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CDS29861.1 - 1.6e-25 88.8 12.0 1.1e-06 29.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 CDS29861.1 - 0.0051 16.7 0.8 0.18 11.7 0.0 3.2 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDS29861.1 - 0.017 15.4 0.2 0.5 10.7 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DAGK_acc PF00609.19 CDS29862.2 - 8.6e-43 146.4 0.0 1.5e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CDS29862.2 - 6.3e-25 87.2 0.0 1.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.7 CDS29862.2 - 1.5e-09 38.3 4.4 1.4e-06 28.8 0.2 2.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29862.2 - 2.2e-09 37.7 0.7 0.00011 22.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) C1_1 PF00130.22 CDS29862.2 - 1.3e-07 31.4 26.8 4.6e-06 26.4 12.8 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_3 PF13606.6 CDS29862.2 - 6.9e-05 22.9 0.1 1.1 10.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDS29862.2 - 0.00051 20.3 0.2 0.35 11.3 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS29862.2 - 0.18 12.3 0.3 38 5.0 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat MARVEL PF01284.23 CDS29864.1 - 8.9e-10 38.8 21.8 2.1e-09 37.6 21.8 1.6 1 1 0 1 1 1 1 Membrane-associating domain UNC-79 PF14776.6 CDS29864.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF2070 PF09843.9 CDS29864.1 - 2.3 6.4 9.1 2.9 6.1 9.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NUDIX_2 PF13869.6 CDS29865.1 - 1.3e-73 246.6 0.0 1.5e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 CDS29865.1 - 0.052 13.6 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain VIGSSK PF14773.6 CDS29872.2 - 1.5 9.0 9.1 1.7 8.8 1.3 3.4 2 2 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal fn3 PF00041.21 CDS29873.2 - 3e-13 49.9 1.6 5.2e-06 26.7 0.1 2.8 3 0 0 3 3 3 2 Fibronectin type III domain Tissue_fac PF01108.17 CDS29873.2 - 6.8e-07 29.1 0.4 0.033 14.0 0.1 2.4 2 1 0 2 2 2 2 Tissue factor fn3_2 PF16893.5 CDS29873.2 - 0.00026 21.1 0.1 0.48 10.6 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain F5_F8_type_C PF00754.25 CDS29873.2 - 1 9.5 3.9 6.5 6.9 0.0 2.7 1 1 0 2 2 2 0 F5/8 type C domain Ribosomal_L4 PF00573.22 CDS29874.1 - 3.4e-27 95.4 0.0 4.7e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Vps54 PF07928.12 CDS29875.1 - 8.3e-25 87.8 1.1 4.1e-24 85.5 1.1 2.3 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 CDS29875.1 - 7.6e-16 58.2 2.8 1.9e-15 57.0 2.8 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 CDS29875.1 - 0.00015 21.7 1.5 0.0011 18.8 0.9 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain YtzH PF14165.6 CDS29875.1 - 0.017 15.5 0.2 0.2 12.1 0.2 2.9 1 0 0 1 1 1 0 YtzH-like protein DUF4763 PF15960.5 CDS29875.1 - 0.047 13.0 1.6 0.36 10.1 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) COG2 PF06148.11 CDS29875.1 - 0.33 11.0 4.0 10 6.2 0.0 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SBF PF01758.16 CDS29876.1 - 9.1e-23 80.9 1.8 1.5e-22 80.2 1.8 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family RNase_T PF00929.24 CDS29878.1 - 1.5e-12 48.4 0.0 2.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RVT_1 PF00078.27 CDS29882.1 - 9.6e-13 48.1 0.1 1.3e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDS29883.1 - 2.7e-10 40.1 0.2 4.9e-10 39.3 0.2 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS29883.1 - 2e-05 24.2 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AT_hook PF02178.19 CDS29884.1 - 0.11 12.4 3.1 0.33 11.0 3.1 1.8 1 0 0 1 1 1 0 AT hook motif SH3_9 PF14604.6 CDS29885.1 - 1.5e-09 37.5 0.1 2.4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH2 PF00017.24 CDS29885.1 - 1.6e-07 31.4 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDS29885.1 - 1.4e-06 27.8 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS29885.1 - 0.012 15.3 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain SH2_2 PF14633.6 CDS29885.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 SH2 domain DUF4201 PF13870.6 CDS29886.1 - 0.0066 16.2 11.8 0.0066 16.2 11.8 7.0 1 1 6 7 7 7 3 Domain of unknown function (DUF4201) LPP PF04728.13 CDS29886.1 - 0.086 13.2 0.1 0.086 13.2 0.1 7.6 10 1 1 11 11 11 0 Lipoprotein leucine-zipper SCP-1 PF05483.12 CDS29887.1 - 2.3e-07 29.3 7.1 3e-07 28.9 7.1 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) LRR_4 PF12799.7 CDS29888.1 - 3e-09 37.0 7.2 3.1e-06 27.4 0.2 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS29888.1 - 4.4e-09 36.1 0.7 1.2e-08 34.6 0.7 1.6 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 CDS29888.1 - 2.4e-07 30.4 1.0 2.4e-07 30.4 1.0 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 CDS29888.1 - 0.13 12.3 6.1 2 8.7 0.3 4.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CDS29888.1 - 3.1 8.7 11.3 22 6.1 0.1 4.6 5 1 0 5 5 5 0 Leucine Rich Repeat Na_H_Exchanger PF00999.21 CDS29890.1 - 4.8e-58 196.8 40.0 5.7e-58 196.5 40.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C2H2_2 PF12756.7 CDS29893.1 - 3.9e-07 30.3 4.7 0.015 15.6 0.4 3.7 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDS29893.1 - 5.8e-05 23.3 11.8 0.069 13.6 0.2 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29893.1 - 0.0033 18.1 8.5 0.67 10.9 0.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 CDS29893.1 - 0.27 11.7 2.8 0.68 10.4 0.0 2.9 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Sigma70_ner PF04546.13 CDS29893.1 - 0.43 10.4 4.6 0.82 9.5 4.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TBCA PF02970.16 CDS29893.1 - 0.92 9.9 4.5 2.3 8.6 4.5 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A zf-C2H2_6 PF13912.6 CDS29893.1 - 3.4 7.8 11.3 0.091 12.8 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger V_ATPase_I PF01496.19 CDS29893.1 - 5.9 4.7 4.7 9.5 4.0 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CDS29896.1 - 1.1e-60 205.2 0.0 1.8e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29896.1 - 1.3e-30 106.6 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS29896.1 - 0.013 14.3 0.0 0.032 13.0 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDS29896.1 - 0.054 13.4 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cation_efflux PF01545.21 CDS29897.1 - 2.8e-47 161.1 6.1 2.8e-47 161.1 6.1 2.6 2 1 0 2 2 2 2 Cation efflux family CTD_bind PF04818.13 CDS29898.1 - 0.0019 19.0 0.1 0.005 17.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_11 PF16622.5 CDS29898.1 - 0.016 15.0 0.4 0.016 15.0 0.4 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type PCO_ADO PF07847.12 CDS29899.1 - 2.1e-42 144.9 0.0 4.3e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 PCO_ADO Cupin_1 PF00190.22 CDS29899.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Cupin IF-2B PF01008.17 CDS29900.1 - 5.8e-54 183.2 0.3 7.3e-54 182.9 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phosphodiest PF01663.22 CDS29901.1 - 6.7e-20 72.0 0.2 9.1e-12 45.2 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase TMEM154 PF15102.6 CDS29901.1 - 0.0055 16.6 1.8 0.0097 15.8 1.8 1.3 1 0 0 1 1 1 1 TMEM154 protein family MGC-24 PF05283.11 CDS29901.1 - 0.019 15.5 4.4 0.034 14.6 4.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Metalloenzyme PF01676.18 CDS29901.1 - 0.033 13.5 0.2 0.055 12.8 0.2 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily AJAP1_PANP_C PF15298.6 CDS29901.1 - 0.46 10.7 8.0 0.74 10.0 8.0 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF599 PF04654.12 CDS29901.1 - 0.92 8.9 3.2 1.6 8.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SSP160 PF06933.11 CDS29901.1 - 1.7 6.7 10.8 2.3 6.3 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Reprolysin_2 PF13574.6 CDS29902.2 - 1.2e-28 100.4 0.0 2.2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDS29902.2 - 3.9e-21 76.1 0.0 1e-20 74.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDS29902.2 - 1.2e-14 54.9 0.4 2.8e-14 53.7 0.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CDS29902.2 - 4.5e-12 46.6 28.0 4.5e-12 46.6 28.0 3.1 4 0 0 4 4 4 1 Disintegrin Reprolysin_4 PF13583.6 CDS29902.2 - 1.9e-09 37.4 0.1 3.7e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CDS29902.2 - 3.4e-06 27.4 0.0 8.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CDS29902.2 - 6.9e-05 22.8 0.1 0.00015 21.8 0.1 1.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Ad_cyc_g-alpha PF08509.11 CDS29902.2 - 0.92 9.3 6.2 15 5.4 0.6 3.0 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Branch PF02485.21 CDS29903.1 - 1.8e-19 70.2 0.2 7.3e-19 68.2 0.2 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Cas_Cas5d PF09704.10 CDS29904.1 - 0.032 14.1 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Vps62 PF06101.11 CDS29905.1 - 0.049 11.9 0.5 0.06 11.6 0.5 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 PDZ PF00595.24 CDS29907.1 - 2.2e-09 37.5 0.0 5.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS29907.1 - 9.7e-08 31.7 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain HLH PF00010.26 CDS29912.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain EF-hand_8 PF13833.6 CDS29912.1 - 0.14 12.0 0.6 0.45 10.4 0.2 2.0 2 0 0 2 2 2 0 EF-hand domain pair TFIIA PF03153.13 CDS29915.2 - 1.3e-38 134.1 7.3 3.5e-24 86.6 2.9 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PsbQ PF05757.11 CDS29915.2 - 0.13 12.0 1.0 0.2 11.4 1.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) MBD_C PF14048.6 CDS29916.1 - 0.042 14.5 0.1 0.11 13.2 0.1 1.7 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Ras PF00071.22 CDS29917.1 - 3.8e-48 163.1 0.0 5e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS29917.1 - 5.1e-19 68.7 0.0 2.4e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS29917.1 - 1.6e-05 24.4 0.0 4.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS29917.1 - 0.004 16.7 0.0 0.034 13.7 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS29917.1 - 0.0099 15.8 0.0 4.3 7.2 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase Ribosomal_L23 PF00276.20 CDS29918.1 - 8.1e-17 61.4 3.9 8.1e-17 61.4 3.9 3.2 3 2 0 3 3 3 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CDS29918.1 - 4.3e-15 55.6 3.0 4.3e-15 55.6 3.0 3.2 3 1 0 3 3 3 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CDS29918.1 - 0.16 11.8 3.3 0.72 9.7 0.2 2.5 2 1 0 2 2 2 0 Sulfurtransferase TusA L51_S25_CI-B8 PF05047.16 CDS29919.1 - 8e-08 32.1 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Diphtheria_R PF01324.19 CDS29919.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, R domain DUF553 PF04473.12 CDS29921.1 - 0.003 17.1 0.1 0.021 14.3 0.1 2.4 1 1 0 1 1 1 1 Transglutaminase-like domain Transglut_core PF01841.19 CDS29921.1 - 0.024 15.1 0.0 0.075 13.5 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily SPRY PF00622.28 CDS29923.1 - 0.00067 19.8 0.0 0.0009 19.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Pkinase_Tyr PF07714.17 CDS29924.1 - 7.2e-60 202.4 0.0 2.6e-32 112.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS29924.1 - 5.4e-27 94.8 0.0 9.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GTPase_binding PF09027.10 CDS29924.1 - 1.2e-08 34.8 0.5 4.3e-08 33.0 0.1 2.2 2 0 0 2 2 2 1 GTPase binding SH3_1 PF00018.28 CDS29924.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF716 PF04819.12 CDS29925.1 - 6.4e-17 61.5 12.6 7.9e-16 57.9 12.6 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF716) TMEM239 PF15841.5 CDS29925.1 - 0.099 12.5 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 239 family zf-C2H2 PF00096.26 CDS29926.1 - 2.1e-18 65.6 36.8 2.9e-05 24.3 0.9 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS29926.1 - 8.9e-17 60.3 34.0 0.0014 19.3 0.6 6.9 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS29926.1 - 3.1e-10 40.0 11.6 4.2e-07 30.1 1.1 9.0 10 0 0 10 10 9 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS29926.1 - 9e-06 25.8 20.8 0.12 12.7 0.0 6.1 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS29926.1 - 0.00082 19.7 19.5 0.26 11.7 0.1 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDS29926.1 - 0.00098 18.8 24.3 0.018 14.8 0.3 5.7 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CDS29926.1 - 0.0051 17.1 23.0 1.2 9.5 3.3 5.2 3 1 2 5 5 5 2 C2H2 type zinc-finger (2 copies) NAD_Gly3P_dh_C PF07479.14 CDS29926.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Zn-C2H2_12 PF18112.1 CDS29926.1 - 0.28 11.7 16.2 0.6 10.6 0.4 6.2 6 1 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 CDS29926.1 - 0.28 11.0 0.1 0.28 11.0 0.1 6.3 7 0 0 7 7 7 0 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 CDS29926.1 - 5.8 6.8 7.7 2.1 8.2 0.1 3.7 2 1 1 3 3 3 0 Rad50 zinc hook motif RecO_C PF02565.15 CDS29927.1 - 0.082 12.7 0.2 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Recombination protein O C terminal XOO_2897-deam PF14440.6 CDS29927.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Ldh_1_C PF02866.18 CDS29929.1 - 3.9e-43 147.3 0.0 8e-43 146.3 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDS29929.1 - 2e-38 131.6 0.9 3.1e-38 131.0 0.9 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Lipocalin_7 PF14651.6 CDS29930.1 - 0.017 15.1 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family GDE_N PF12439.8 CDS29930.1 - 0.055 12.9 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF2850 PF11012.8 CDS29930.1 - 0.091 13.1 0.3 0.16 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) ATG16 PF08614.11 CDS29931.1 - 1.7e-07 31.7 17.6 1.7e-07 31.7 17.6 10.8 7 4 3 11 11 11 2 Autophagy protein 16 (ATG16) Raptor_N PF14538.6 CDS29931.1 - 4.1e-05 23.6 0.1 0.23 11.4 0.0 3.8 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain BST2 PF16716.5 CDS29931.1 - 0.0068 17.0 3.8 0.0068 17.0 3.8 12.0 8 3 4 13 13 13 1 Bone marrow stromal antigen 2 Surface_antigen PF11054.8 CDS29931.1 - 0.0081 15.9 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen DUF1376 PF07120.11 CDS29931.1 - 0.011 16.0 0.2 0.056 13.8 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) Med29 PF11568.8 CDS29931.1 - 0.015 15.5 0.0 0.015 15.5 0.0 5.7 4 1 1 5 5 5 0 Mediator complex subunit 29 Lipase_GDSL PF00657.22 CDS29931.1 - 0.049 13.6 0.6 11 6.0 0.0 3.7 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase FAM194 PF14977.6 CDS29931.1 - 0.67 9.2 2.7 44 3.3 0.1 3.8 3 0 0 3 3 3 0 FAM194 protein FPP PF05911.11 CDS29933.1 - 0.00025 19.4 16.8 0.00025 19.4 16.8 6.7 1 1 4 7 7 7 2 Filament-like plant protein, long coiled-coil Med9 PF07544.13 CDS29933.1 - 0.00055 20.0 0.4 0.00055 20.0 0.4 9.1 8 1 2 10 10 10 2 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 CDS29933.1 - 0.0025 17.8 1.6 0.0025 17.8 1.6 11.8 10 3 1 11 11 11 4 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 CDS29933.1 - 0.0039 16.3 18.7 0.0039 16.3 18.7 6.9 3 2 3 7 7 7 2 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 CDS29933.1 - 0.88 9.1 110.1 0.51 9.9 7.8 6.7 2 2 1 5 5 5 0 Intermediate filament protein DUF3584 PF12128.8 CDS29933.1 - 1.2 6.5 94.0 0.33 8.4 9.2 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 CDS29933.1 - 7.4 6.6 17.0 2 8.4 0.2 6.7 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Collagen PF01391.18 CDS29935.1 - 1.4e-204 662.1 757.1 8e-10 38.3 27.0 29.8 7 7 21 29 29 29 29 Collagen triple helix repeat (20 copies) C4 PF01413.19 CDS29935.1 - 2.4e-60 201.7 4.4 1e-29 103.2 0.6 2.1 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Metallophos PF00149.28 CDS29939.1 - 3.9e-39 135.3 0.0 5.1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ARGLU PF15346.6 CDS29940.1 - 3.7e-29 101.6 60.0 3.7e-29 101.6 60.0 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 HisK_N PF09385.10 CDS29940.1 - 0.47 10.4 5.5 0.99 9.4 5.5 1.5 1 0 0 1 1 1 0 Histidine kinase N terminal Peptidase_C14 PF00656.22 CDS29941.1 - 1.5e-38 133.2 0.0 2.2e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.7 CDS29941.1 - 1e-19 70.8 1.5 1.9e-07 31.6 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS29941.1 - 2.9e-15 56.4 2.1 0.00055 20.4 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS29941.1 - 1.8e-14 53.6 2.5 0.00032 20.9 0.1 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS29941.1 - 9.9e-14 50.1 3.8 0.00093 19.5 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CDS29941.1 - 3.7e-12 46.1 7.3 0.026 15.0 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Methyltransf_PK PF05891.12 CDS29943.1 - 1.2e-66 224.3 0.0 1.5e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CDS29943.1 - 9.2e-07 29.5 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS29943.1 - 2.7e-05 24.7 0.0 4.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS29943.1 - 0.00025 21.7 0.0 0.00042 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS29943.1 - 0.0046 16.8 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 CDS29943.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.3 1 1 0 1 1 1 0 Spermine/spermidine synthase domain MTS PF05175.14 CDS29943.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Nucleoporin_FG PF13634.6 CDS29944.1 - 7.8e-32 110.0 292.1 1.9e-12 47.8 19.7 13.6 6 3 5 12 12 12 8 Nucleoporin FG repeat region ANAPC4_WD40 PF12894.7 CDS29944.1 - 0.034 14.4 0.0 1.5 9.1 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 CDS29944.1 - 0.076 13.6 1.4 0.18 12.3 1.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Nucleocap_ssRNA PF11128.8 CDS29945.1 - 0.082 12.6 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid LRR_4 PF12799.7 CDS29945.1 - 0.13 12.7 10.5 4.5 7.8 0.5 5.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Acatn PF13000.7 CDS29946.2 - 6.4e-116 388.0 3.2 9.4e-116 387.5 3.2 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Acatn PF13000.7 CDS29947.1 - 2.2e-45 155.2 2.8 2.6e-45 155.0 2.8 1.1 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Acatn PF13000.7 CDS29949.1 - 2e-50 171.8 0.5 5.2e-50 170.5 0.5 1.7 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 adh_short PF00106.25 CDS29951.1 - 2.5e-24 85.8 0.3 2.5e-23 82.6 0.3 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDS29951.1 - 2.5e-17 63.2 0.2 7.7e-09 35.4 0.1 3.2 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS29951.1 - 0.026 14.4 0.2 0.066 13.1 0.2 1.6 1 0 0 1 1 1 0 KR domain Mito_carr PF00153.27 CDS29952.1 - 2.5e-61 203.6 3.0 2.2e-24 85.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CDS29952.1 - 1e-09 38.7 6.6 1.3e-05 25.5 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS29952.1 - 1.6e-07 30.4 7.9 0.013 15.0 0.5 4.6 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 CDS29952.1 - 4.2e-07 29.4 10.3 0.0057 16.5 1.2 4.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 CDS29952.1 - 0.00016 21.5 5.2 0.13 12.1 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS29952.1 - 0.001 18.4 1.0 0.001 18.4 1.0 3.8 4 1 0 4 4 4 1 EF hand EF-hand_10 PF14788.6 CDS29952.1 - 0.12 12.2 0.7 1 9.3 0.1 2.3 2 0 0 2 2 2 0 EF hand Serine_protease PF18405.1 CDS29952.1 - 0.22 10.7 0.6 2.2 7.4 0.0 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF2464 PF10240.9 CDS29953.1 - 2.8e-38 132.0 0.0 6.8e-32 111.0 0.0 2.0 1 1 1 2 2 2 2 Multivesicular body subunit 12 ACR_tran PF00873.19 CDS29954.1 - 0.45 8.1 1.0 0.67 7.5 1.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Ephrin_lbd PF01404.19 CDS29955.2 - 4.5e-38 131.1 0.0 9.5e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase_Tyr PF07714.17 CDS29955.2 - 1.1e-08 34.7 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_rec_like PF07699.13 CDS29955.2 - 2.5e-06 27.1 6.3 2.5e-06 27.1 6.3 2.1 3 0 0 3 3 3 1 Putative ephrin-receptor like Zn_Tnp_IS1 PF03811.13 CDS29955.2 - 0.035 13.8 0.7 18 5.1 0.0 3.3 3 0 0 3 3 3 0 InsA N-terminal domain fn3 PF00041.21 CDS29955.2 - 0.068 13.5 0.1 0.96 9.8 0.0 2.9 3 0 0 3 3 3 0 Fibronectin type III domain Pkinase PF00069.25 CDS29956.1 - 5.1e-68 229.3 0.0 7.1e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29956.1 - 4.6e-41 140.8 0.0 1.4e-40 139.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDS29956.1 - 2.1e-16 60.0 0.0 5.2e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CDS29956.1 - 7.1e-06 25.1 0.0 1.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDS29956.1 - 9.2e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS29956.1 - 0.043 13.2 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 CDS29956.1 - 0.21 11.2 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain RFC1 PF08519.12 CDS29957.1 - 3.5e-48 163.7 0.0 1.2e-47 162.0 0.0 2.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 CDS29957.1 - 9.9e-15 54.7 0.0 3.1e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 CDS29957.1 - 1.6e-13 51.2 0.0 4.9e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 CDS29957.1 - 6.6e-06 26.0 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain AAA_30 PF13604.6 CDS29957.1 - 0.00038 20.2 0.0 0.00094 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain BRCT_2 PF16589.5 CDS29957.1 - 0.0037 17.7 0.0 0.0092 16.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RuvB_N PF05496.12 CDS29957.1 - 0.0046 16.7 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS29957.1 - 0.0071 16.7 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDS29957.1 - 0.027 14.4 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain DNA_pol3_delta PF06144.13 CDS29957.1 - 0.03 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_22 PF13401.6 CDS29957.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDS29957.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BTB PF00651.31 CDS29958.1 - 3.8e-23 81.8 1.0 1.6e-19 70.2 0.1 2.4 1 1 1 2 2 2 2 BTB/POZ domain DUF2182 PF09948.9 CDS29958.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) zf-CCCH PF00642.24 CDS29959.1 - 1.3e-10 40.9 12.0 2.7e-09 36.7 2.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS29959.1 - 3.5e-05 23.7 11.9 0.00034 20.5 3.5 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CDS29959.1 - 0.00067 19.4 1.0 0.00067 19.4 1.0 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 CDS29959.1 - 4.2 8.1 17.5 0.62 10.8 0.3 3.6 4 0 0 4 4 4 0 Torus domain DDDD PF10161.9 CDS29960.1 - 1.2e-12 47.4 0.0 2.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Putative mitochondrial precursor protein PDEase_I PF00233.19 CDS29961.2 - 2.6e-55 187.7 0.6 4.4e-55 187.0 0.6 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF4050 PF13259.6 CDS29961.2 - 1.9 8.8 9.8 7.9 6.8 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) TIM PF00121.18 CDS29962.1 - 2.1e-95 318.8 0.0 2.3e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MIF4G PF02854.19 CDS29962.1 - 0.053 13.1 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain Prefoldin PF02996.17 CDS29963.1 - 4.9e-25 87.8 0.1 6e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CDS29963.1 - 0.012 15.6 2.7 0.066 13.2 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 CDS29963.1 - 0.019 15.0 0.7 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sacchrp_dh_NADP PF03435.18 CDS29963.1 - 0.084 13.1 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fer2_3 PF13085.6 CDS29964.1 - 4.4e-32 110.3 0.2 8e-32 109.5 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDS29964.1 - 3.9e-08 33.7 6.6 3.9e-08 33.7 6.6 2.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDS29964.1 - 2.3e-07 31.2 6.5 2.3e-07 31.2 6.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDS29964.1 - 1e-06 28.7 3.5 1e-06 28.7 3.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CDS29964.1 - 0.005 17.4 4.9 0.005 17.4 4.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CDS29964.1 - 0.69 9.9 8.0 0.21 11.5 3.7 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain BUD22 PF09073.10 CDS29965.1 - 2e-05 24.2 4.2 2e-05 24.2 4.2 3.3 1 1 1 2 2 2 1 BUD22 PyocinActivator PF11112.8 CDS29965.1 - 0.17 12.1 0.3 32 4.7 0.0 2.7 2 0 0 2 2 2 0 Pyocin activator protein PrtN MMR1 PF08505.10 CDS29965.1 - 6.1 7.1 16.5 0.37 11.1 9.7 2.0 1 1 1 2 2 2 0 Mitochondrial Myo2 receptor-related protein SUZ PF12752.7 CDS29967.1 - 1.5e-10 41.7 2.6 3.6e-10 40.4 0.2 2.6 2 0 0 2 2 2 1 SUZ domain GAS PF13851.6 CDS29968.2 - 0.005 16.2 9.4 0.005 16.2 9.4 4.3 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding CH PF00307.31 CDS29968.2 - 0.41 10.8 5.2 0.67 10.2 0.0 3.6 4 1 1 5 5 5 0 Calponin homology (CH) domain DUF3818 PF12825.7 CDS29968.2 - 1.7 7.6 17.5 0.04 12.9 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) FliD_C PF07195.12 CDS29968.2 - 3 7.2 14.6 0.071 12.5 0.3 3.7 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Fez1 PF06818.15 CDS29968.2 - 4.1 7.8 61.1 93 3.4 16.4 4.3 2 1 1 3 3 3 0 Fez1 DUF2263 PF10021.9 CDS29968.2 - 7.6 6.9 7.2 0.81 10.0 1.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) zinc_ribbon_12 PF11331.8 CDS29968.2 - 8.9 6.2 7.3 3.8 7.4 2.3 3.1 3 1 0 3 3 3 0 Probable zinc-ribbon domain DUF4094 PF13334.6 CDS29968.2 - 9.6 6.7 20.0 0.11 12.9 2.6 4.3 3 1 0 4 4 4 0 Domain of unknown function (DUF4094) DUF1126 PF06565.12 CDS29969.2 - 7e-92 302.2 0.0 6.6e-35 119.1 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain F-box PF00646.33 CDS29970.2 - 0.0008 19.2 0.4 0.0035 17.2 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDS29970.2 - 0.6 10.0 2.2 0.63 10.0 0.3 2.1 2 0 0 2 2 2 0 F-box-like SF3A2 PF16835.5 CDS29973.1 - 1.1e-37 128.3 0.4 1.9e-37 127.5 0.4 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDS29973.1 - 6.2e-07 29.6 2.0 6.2e-07 29.6 2.0 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CDS29973.1 - 4.9e-05 23.3 1.6 7.6e-05 22.7 1.1 1.5 1 1 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 CDS29973.1 - 0.64 9.6 3.3 1.1 8.8 3.3 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DNA_pol_E_B PF04042.16 CDS29974.1 - 2.1e-27 95.8 0.0 1.1e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 CDS29974.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal GyrI-like PF06445.15 CDS29975.1 - 0.034 14.4 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 GyrI-like small molecule binding domain Pkinase PF00069.25 CDS29976.2 - 4.3e-62 209.9 0.0 6.6e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CDS29976.2 - 1.6e-49 169.0 0.0 2.5e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CDS29976.2 - 1e-43 149.5 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS29976.2 - 3.3e-05 22.8 1.6 0.00011 21.1 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase TFIIA PF03153.13 CDS29976.2 - 0.00042 20.5 27.6 0.00042 20.5 27.6 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 CDS29976.2 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS29976.2 - 0.0096 15.9 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3357 PF11837.8 CDS29976.2 - 0.043 14.3 0.9 0.16 12.4 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) FTA2 PF13095.6 CDS29976.2 - 0.06 13.0 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDS29976.2 - 0.11 11.9 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_A_bac PF01000.26 CDS29977.1 - 1.7e-29 102.4 0.0 2.8e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDS29977.1 - 2.1e-17 62.3 0.0 3.4e-17 61.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNase_H2-Ydr279 PF09468.10 CDS29979.2 - 0.0046 17.2 0.4 0.0077 16.4 0.3 1.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Lung_7-TM_R PF06814.13 CDS29980.2 - 1.3e-65 221.5 22.6 1.7e-65 221.2 22.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor FixQ PF05545.11 CDS29980.2 - 0.15 12.0 5.1 0.079 12.9 1.0 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Na_K-ATPase PF00287.18 CDS29981.1 - 3.3e-49 167.6 0.6 4e-49 167.3 0.6 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Kelch_1 PF01344.25 CDS29982.2 - 2.5e-22 78.2 21.1 5.9e-09 35.4 0.1 7.7 8 1 0 8 8 8 4 Kelch motif Kunitz_BPTI PF00014.23 CDS29982.2 - 7.3e-16 58.2 1.6 2.4e-15 56.5 1.6 1.9 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kelch_6 PF13964.6 CDS29982.2 - 5.6e-12 45.5 3.3 2.1e-05 24.6 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CDS29982.2 - 2e-06 27.7 3.9 0.049 13.6 0.0 6.4 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS29982.2 - 0.00017 21.8 9.9 0.034 14.4 0.0 6.3 7 0 0 7 7 7 1 Galactose oxidase, central domain zf-RING_2 PF13639.6 CDS29986.1 - 2e-15 56.9 30.1 2.4e-08 34.2 14.5 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CDS29986.1 - 1.5e-11 44.4 29.3 3.4e-06 27.2 5.9 3.0 1 1 1 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDS29986.1 - 1.2e-09 37.8 30.4 3.1e-05 23.7 5.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS29986.1 - 3.3e-08 33.2 29.9 0.00013 21.7 15.8 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS29986.1 - 4.4e-08 32.9 26.7 3.1e-06 26.9 11.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDS29986.1 - 3.2e-07 30.3 22.0 0.0012 18.9 4.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDS29986.1 - 8.8e-06 25.3 5.9 8.8e-06 25.3 5.9 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CDS29986.1 - 2.3e-05 24.3 24.6 0.0052 16.8 8.7 3.1 3 1 1 4 4 4 2 RING-type zinc-finger zf-RING_5 PF14634.6 CDS29986.1 - 4.6e-05 23.3 30.1 0.014 15.3 7.3 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDS29986.1 - 0.0019 18.3 2.1 0.0019 18.3 2.1 3.3 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CDS29986.1 - 0.0046 16.7 4.4 0.0046 16.7 4.4 3.0 3 0 0 3 3 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 CDS29986.1 - 0.012 15.5 28.6 0.023 14.6 12.5 3.3 2 2 2 4 4 4 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 CDS29986.1 - 0.054 13.2 10.6 0.42 10.3 3.0 3.6 3 0 0 3 3 3 0 P-11 zinc finger DUF1244 PF06844.11 CDS29986.1 - 0.45 10.7 9.7 0.12 12.6 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1244) FANCL_C PF11793.8 CDS29986.1 - 2.1 8.6 26.0 0.47 10.7 5.1 3.3 2 2 0 2 2 2 0 FANCL C-terminal domain A_deaminase PF00962.22 CDS29988.1 - 1.1e-07 31.5 0.2 1.3e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CDS29988.1 - 0.0012 18.2 0.1 0.0013 18.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family PNP_UDP_1 PF01048.20 CDS29989.2 - 8.6e-44 149.5 0.2 1.1e-43 149.2 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Mo-nitro_C PF06967.11 CDS29989.2 - 0.043 13.8 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Raftlin PF15250.6 CDS29990.2 - 0.055 12.2 1.1 0.079 11.7 1.1 1.1 1 0 0 1 1 1 0 Raftlin Pkinase PF00069.25 CDS29990.2 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Kunitz_BPTI PF00014.23 CDS29991.1 - 2.8e-38 129.9 14.5 1.8e-19 69.7 4.0 2.0 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Trnau1ap PF17654.1 CDS29991.1 - 0.024 15.5 0.0 9.2 7.2 0.0 2.1 1 1 1 2 2 2 0 Selenocysteine tRNA 1 associated proteins Methyltransf_15 PF09445.10 CDS29991.1 - 0.027 14.1 1.8 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF1638 PF07796.11 CDS29991.1 - 0.79 9.8 4.2 3.8 7.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) Pkinase PF00069.25 CDS29992.1 - 5.1e-71 239.1 0.0 5.6e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29992.1 - 4.8e-36 124.4 0.0 5.6e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS29992.1 - 8e-07 28.3 0.3 9.4e-07 28.1 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CDS29992.1 - 0.012 14.6 1.7 0.015 14.3 0.2 1.9 1 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CDS29992.1 - 0.023 14.6 0.2 0.054 13.4 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDS29992.1 - 0.023 14.3 0.9 0.039 13.5 0.9 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase PIP49_C PF12260.8 CDS29992.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Tubulin PF00091.25 CDS29993.2 - 1.2e-67 227.9 0.0 1.6e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS29993.2 - 2.4e-51 173.2 0.0 4e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS29993.2 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain zf-RING_2 PF13639.6 CDS29994.1 - 5.1e-07 29.9 10.2 7.9e-07 29.3 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS29994.1 - 8.1e-07 28.8 8.0 1.2e-06 28.2 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS29994.1 - 1.1e-06 28.3 10.2 3.6e-06 26.7 10.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS29994.1 - 1.7e-06 27.8 7.5 2.5e-06 27.2 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS29994.1 - 0.0038 17.2 7.4 0.0071 16.3 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDS29994.1 - 0.012 15.5 9.9 0.74 9.7 10.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDS29994.1 - 0.047 13.7 7.7 0.098 12.6 7.7 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 CDS29994.1 - 0.23 11.8 14.4 1.1 9.6 14.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDS29994.1 - 0.4 10.5 7.4 2.1 8.2 3.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CDS29994.1 - 0.83 9.7 5.5 1.6 8.8 5.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 CDS29994.1 - 1.9 8.7 7.3 3.9 7.7 7.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FdhE PF04216.12 CDS29994.1 - 4.4 7.1 7.7 6.1 6.6 7.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Zn_ribbon_17 PF17120.5 CDS29994.1 - 4.5 7.0 10.0 21 4.8 9.9 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 CDS29996.1 - 2.3e-46 158.3 0.0 1.5e-45 155.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS29996.1 - 1.2e-20 73.8 0.6 5.8e-20 71.7 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 CDS29996.1 - 0.027 14.1 0.1 0.076 12.6 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDS29996.1 - 0.091 12.7 0.2 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family SH2 PF00017.24 CDS29997.1 - 5.3e-10 39.3 0.0 2.4e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 SH2 domain Receptor_2B4 PF11465.8 CDS29997.1 - 8.4 6.6 11.1 3.7 7.8 6.4 2.5 1 1 2 3 3 3 0 Natural killer cell receptor 2B4 F-box_4 PF15966.5 CDS30000.1 - 3.6e-35 120.3 0.0 5.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 F-box PRANC PF09372.10 CDS30000.1 - 0.0053 17.0 0.0 0.0081 16.5 0.0 1.3 1 0 0 1 1 1 1 PRANC domain F-box PF00646.33 CDS30000.1 - 0.0072 16.2 0.6 0.016 15.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain TAFII55_N PF04658.13 CDS30002.2 - 5.8e-49 165.9 0.0 1.1e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Pkinase PF00069.25 CDS30004.1 - 1.2e-52 178.9 0.0 3.4e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30004.1 - 6.9e-31 107.5 0.0 1e-13 51.2 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Enolase_C PF00113.22 CDS30005.1 - 7.5e-153 508.0 0.2 1e-152 507.5 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDS30005.1 - 3.5e-61 205.1 0.1 6.2e-61 204.3 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDS30005.1 - 6e-08 32.5 0.0 9.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDS30005.1 - 6e-06 25.6 1.2 1.5e-05 24.3 1.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus TAF6_C PF07571.13 CDS30006.1 - 1.6e-15 57.2 0.0 6.9e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain AAA_lid_7 PF17867.1 CDS30006.1 - 0.087 13.0 0.1 31 4.8 0.0 2.9 3 0 0 3 3 3 0 Midasin AAA lid domain Pkinase PF00069.25 CDS30010.2 - 1.2e-52 178.9 0.0 3.4e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30010.2 - 6.9e-31 107.5 0.0 1e-13 51.2 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase TAFII55_N PF04658.13 CDS30012.2 - 1.3e-31 109.5 0.0 2.6e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF668 PF05003.12 CDS30012.2 - 0.29 11.6 1.4 0.76 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Cupin_8 PF13621.6 CDS30013.1 - 6.7e-35 121.0 0.0 1.1e-34 120.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CDS30013.1 - 0.0039 17.6 0.1 0.0074 16.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CDS30013.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily protein DAGK_cat PF00781.24 CDS30015.2 - 1.4e-15 57.0 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RVT_1 PF00078.27 CDS30016.1 - 4e-21 75.6 0.0 9.1e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDS30016.1 - 1.1e-16 60.7 0.7 1.6e-15 57.0 0.6 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS30016.1 - 2.4e-16 60.0 0.0 8.1e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS30016.1 - 8.6e-08 32.2 0.3 8.6e-08 32.2 0.3 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDS30016.1 - 1.3e-07 31.9 0.0 6.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 CDS30016.1 - 0.0075 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 CDS30016.1 - 0.13 12.9 0.0 0.45 11.2 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease FSA_C PF10479.9 CDS30018.1 - 1.3e-49 169.0 0.3 1e-35 123.1 0.0 3.4 4 0 0 4 4 4 2 Fragile site-associated protein C-terminus Wbp11 PF09429.10 CDS30018.1 - 0.2 12.1 2.8 0.48 10.8 2.8 1.6 1 0 0 1 1 1 0 WW domain binding protein 11 DUF3520 PF12034.8 CDS30019.1 - 1.1 9.3 7.1 0.073 13.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) Thioredoxin_11 PF18078.1 CDS30020.1 - 0.022 14.9 0.6 0.031 14.4 0.6 1.2 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain Cep57_MT_bd PF06657.13 CDS30020.1 - 0.028 14.9 1.0 0.046 14.2 1.0 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Helo_like_N PF17111.5 CDS30020.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins LUC7 PF03194.15 CDS30021.1 - 2.3e-82 276.5 0.9 3.7e-82 275.8 0.9 1.3 1 0 0 1 1 1 1 LUC7 N_terminus NRBF2 PF08961.10 CDS30021.1 - 0.035 13.7 0.4 0.074 12.7 0.4 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator kleA_kleC PF17383.2 CDS30021.1 - 0.39 11.1 1.9 0.62 10.4 0.3 2.2 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A Ribosomal_L28e PF01778.17 CDS30022.1 - 3.9e-33 114.6 0.6 4.8e-33 114.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DnaJ PF00226.31 CDS30024.1 - 1.2e-16 60.6 5.9 2.5e-16 59.5 5.9 1.6 1 0 0 1 1 1 1 DnaJ domain FapA PF03961.13 CDS30024.1 - 0.33 9.5 5.2 0.45 9.1 5.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CDS30024.1 - 0.7 8.7 4.1 0.84 8.5 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 CDS30024.1 - 4.4 6.6 9.7 6.5 6.0 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 CDS30025.1 - 3.7e-51 172.9 1.8 6.1e-51 172.2 0.0 2.3 3 0 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.23 CDS30025.1 - 8.6e-23 81.2 0.0 4e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CDS30025.1 - 9.6e-08 32.1 0.0 7.3e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRA1 PF07304.11 CDS30025.1 - 0.029 14.2 1.5 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) DUF842 PF05811.13 CDS30025.1 - 0.045 13.4 1.8 1.6 8.4 0.1 3.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CompInhib_SCIN PF11546.8 CDS30025.1 - 0.046 13.8 2.7 1 9.4 0.1 3.7 4 0 0 4 4 4 0 Staphylococcal complement inhibitor SCIN Baculo_PEP_C PF04513.12 CDS30025.1 - 0.063 13.3 1.9 0.76 9.8 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 CDS30025.1 - 0.1 13.1 0.2 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.16 CDS30025.1 - 0.14 11.5 0.3 0.37 10.1 0.3 1.7 1 0 0 1 1 1 0 AIG1 family PLU-1 PF08429.11 CDS30025.1 - 0.7 9.0 5.1 3.4 6.8 0.6 2.5 2 0 0 2 2 2 0 PLU-1-like protein Seryl_tRNA_N PF02403.22 CDS30025.1 - 7.2 6.9 8.6 5 7.4 0.2 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BTB PF00651.31 CDS30026.1 - 2.2e-06 27.9 0.0 8.9e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain HTH_48 PF17906.1 CDS30028.1 - 8.4e-06 25.8 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain in Mos1 transposase TPR_2 PF07719.17 CDS30029.2 - 1.3e-10 40.5 4.2 0.008 16.2 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30029.2 - 3.1e-10 39.4 1.4 0.0021 17.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30029.2 - 2.2e-06 28.2 7.0 9.7e-05 22.9 2.1 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30029.2 - 1.4e-05 24.9 0.6 0.033 14.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS30029.2 - 5.3e-05 22.8 4.8 0.07 12.8 0.9 3.1 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 CDS30029.2 - 0.00037 20.7 0.2 0.061 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS30029.2 - 0.00071 19.8 3.9 0.78 10.1 1.3 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30029.2 - 0.0017 19.0 2.8 0.3 12.0 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS30029.2 - 0.0024 18.4 8.3 1.7 9.4 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS30029.2 - 0.0039 17.1 1.2 9.9 6.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS30029.2 - 0.0059 17.1 5.3 0.47 11.0 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS30029.2 - 0.086 13.1 2.8 0.42 10.9 2.1 2.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Rad51 PF08423.11 CDS30030.2 - 1.6e-49 168.5 0.1 1.9e-49 168.3 0.1 1.0 1 0 0 1 1 1 1 Rad51 AAA_28 PF13521.6 CDS30030.2 - 0.00042 20.6 0.0 0.00051 20.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDS30030.2 - 0.01 15.4 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 CDS30031.1 - 1.5e-11 44.1 0.1 9.9e-08 31.5 0.0 2.0 1 1 1 2 2 2 2 Rad51 Rad51 PF08423.11 CDS30032.1 - 1.9e-32 112.5 0.2 2.1e-32 112.4 0.2 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CDS30032.1 - 1.2e-05 24.9 0.1 1.3e-05 24.9 0.1 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CDS30032.1 - 0.00016 21.1 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 CDS30032.1 - 0.019 14.5 0.0 0.02 14.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain Claudin_2 PF13903.6 CDS30035.2 - 0.015 15.0 9.7 0.067 12.9 0.1 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.13 CDS30035.2 - 0.075 13.4 1.1 0.075 13.4 1.1 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) SPATA6 PF14909.6 CDS30036.1 - 6.8e-17 61.9 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 Metallothio_5 PF02067.15 CDS30036.1 - 2.7 8.2 7.2 0.62 10.2 2.4 2.1 2 0 0 2 2 2 0 Metallothionein family 5 RRM_1 PF00076.22 CDS30038.1 - 4e-10 39.4 0.0 0.00022 20.9 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ILVD_EDD PF00920.21 CDS30038.1 - 0.015 13.9 0.6 0.023 13.4 0.6 1.2 1 0 0 1 1 1 0 Dehydratase family RRM_3 PF08777.11 CDS30038.1 - 0.17 11.9 0.0 8 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Transcrip_reg PF01709.20 CDS30038.1 - 0.24 10.8 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TPR_12 PF13424.6 CDS30040.2 - 6.1e-08 32.8 0.0 0.0012 19.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30040.2 - 1.2e-07 31.3 0.0 0.00053 19.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30040.2 - 2.8e-07 30.8 0.0 0.041 14.7 0.0 3.6 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS30040.2 - 7.6e-07 29.6 0.0 0.00063 20.2 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30040.2 - 2.4e-06 27.3 0.0 0.094 13.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30040.2 - 6.6e-06 26.7 0.0 0.0095 16.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30040.2 - 7e-06 25.7 0.0 0.0096 15.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDS30040.2 - 7.1e-06 25.7 0.0 1.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 CDS30040.2 - 6.9e-05 22.6 0.0 0.023 14.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS30040.2 - 0.00043 19.8 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 CDS30040.2 - 0.00057 20.1 0.0 0.19 12.2 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CDS30040.2 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_15 PF13429.6 CDS30040.2 - 0.029 13.6 0.0 1.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS30040.2 - 0.044 14.4 0.0 5.2 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDS30040.2 - 0.075 13.7 0.0 10 7.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDS30040.2 - 0.076 12.7 0.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat dNK PF01712.19 CDS30041.2 - 6.9e-38 130.6 0.0 9.3e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 CDS30041.2 - 9.8e-06 26.1 0.3 2.7e-05 24.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS30041.2 - 0.00035 20.7 0.2 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain CoaE PF01121.20 CDS30041.2 - 0.056 13.1 0.0 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 CDS30041.2 - 0.057 13.7 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CDS30041.2 - 0.099 12.3 0.0 0.58 9.8 0.0 2.1 2 1 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 CDS30041.2 - 0.11 13.0 0.3 2 8.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain Glyco_transf_10 PF00852.19 CDS30042.2 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_transf_10 PF00852.19 CDS30043.1 - 2.6e-25 89.2 0.0 2.9e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term TPR_12 PF13424.6 CDS30045.1 - 9.5e-08 32.2 0.0 0.0014 18.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30045.1 - 1.6e-07 30.9 0.0 0.00061 19.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30045.1 - 4e-07 30.3 0.0 0.048 14.5 0.0 3.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS30045.1 - 1e-06 29.1 0.0 0.00073 20.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30045.1 - 3.5e-06 26.8 0.0 0.11 12.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDS30045.1 - 8.2e-06 25.5 0.0 2.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CDS30045.1 - 9e-06 26.2 0.0 0.011 16.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30045.1 - 1e-05 25.1 0.0 0.011 15.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS30045.1 - 0.0001 22.1 0.0 0.026 14.5 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS30045.1 - 0.00052 19.5 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 CDS30045.1 - 0.00075 19.7 0.0 0.22 12.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CDS30045.1 - 0.027 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_15 PF13429.6 CDS30045.1 - 0.039 13.2 0.0 2.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS30045.1 - 0.064 13.9 0.0 5.9 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDS30045.1 - 0.093 12.4 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.14 CDS30045.1 - 0.1 13.3 0.0 12 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Orf78 PF06024.12 CDS30048.2 - 0.14 12.4 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Adipogenin PF15202.6 CDS30048.2 - 0.23 11.5 3.3 1.1 9.3 1.9 2.0 1 1 1 2 2 2 0 Adipogenin DUF1375 PF07119.12 CDS30048.2 - 0.26 11.7 0.2 0.26 11.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1375) PRIMA1 PF16101.5 CDS30049.1 - 0.089 12.8 1.7 0.12 12.4 1.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CDS30049.1 - 2.8 7.4 9.4 3.4 7.1 8.9 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1700 PF08006.11 CDS30051.2 - 0.27 10.8 12.2 0.3 10.6 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF334 PF03904.13 CDS30052.2 - 6.2 6.3 6.0 7.3 6.1 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF4391 PF14335.6 CDS30053.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) EF-hand_7 PF13499.6 CDS30055.1 - 0.069 13.6 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain pair FH2 PF02181.23 CDS30056.2 - 1.6e-11 44.0 0.0 1.9e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain PAN_4 PF14295.6 CDS30057.1 - 0.013 15.3 1.2 0.045 13.7 1.2 1.9 1 0 0 1 1 1 0 PAN domain PHD PF00628.29 CDS30058.1 - 7.1e-15 54.6 20.8 1.1e-08 34.9 7.0 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 CDS30058.1 - 8.6e-05 22.0 11.2 0.00015 21.2 1.4 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 CDS30058.1 - 0.00011 22.0 17.1 0.028 14.3 8.6 2.5 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Requiem_N PF14051.6 CDS30058.1 - 0.0063 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. C1_2 PF03107.16 CDS30058.1 - 0.052 13.9 0.3 0.052 13.9 0.3 2.9 3 0 0 3 3 3 0 C1 domain zf-PHD-like PF15446.6 CDS30058.1 - 0.22 11.1 12.8 0.032 13.8 4.2 2.5 1 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 CDS30058.1 - 8.2 6.6 24.1 42 4.3 8.3 3.1 1 1 1 2 2 2 0 PHD-finger Ank_2 PF12796.7 CDS30060.1 - 2.5e-43 146.5 3.5 2.2e-12 47.4 0.0 3.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30060.1 - 3.3e-27 94.5 0.4 1.8e-11 44.3 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CDS30060.1 - 8.6e-24 82.9 5.0 0.00048 20.4 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CDS30060.1 - 9.2e-23 77.9 1.8 0.0042 17.5 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CDS30060.1 - 1.6e-22 79.2 1.1 7.7e-07 29.3 0.0 5.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) RPAP1_N PF08621.10 CDS30062.1 - 0.18 11.6 0.5 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal Pkinase PF00069.25 CDS30064.2 - 1.1e-61 208.5 0.0 1.8e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30064.2 - 4.6e-25 88.4 0.0 6.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS30064.2 - 0.0039 16.5 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HLH PF00010.26 CDS30064.2 - 0.034 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain RGS PF00615.19 CDS30064.2 - 1.9 8.8 5.4 0.62 10.3 1.3 2.2 3 0 0 3 3 3 0 Regulator of G protein signaling domain WGG PF10273.9 CDS30065.2 - 4.2e-14 53.0 1.4 8.1e-14 52.1 0.3 1.9 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Microvir_H PF04687.12 CDS30065.2 - 0.051 12.9 0.3 0.062 12.7 0.3 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) RNA_pol_3_Rpc31 PF11705.8 CDS30065.2 - 0.19 12.0 3.9 0.21 11.8 3.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribonuclease_3 PF00636.26 CDS30066.2 - 0.00088 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 CDS30066.2 - 0.0097 16.6 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CDS30066.2 - 0.01 16.0 0.0 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 Ribonuclease-III-like Peptidase_M18 PF02127.15 CDS30067.1 - 5.6e-154 513.1 0.0 2.2e-152 507.8 0.0 2.2 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) HTH_psq PF05225.16 CDS30067.1 - 8.1e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Peptidase_M42 PF05343.14 CDS30067.1 - 0.0097 15.0 0.0 0.51 9.3 0.1 2.5 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Kelch_1 PF01344.25 CDS30072.1 - 3.5e-63 209.0 23.5 5.5e-16 57.9 0.0 7.9 6 2 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDS30072.1 - 4.7e-29 99.7 10.4 4.6e-09 36.2 0.0 7.7 1 1 5 6 6 6 5 Kelch motif BTB PF00651.31 CDS30072.1 - 5e-28 97.6 0.0 1.3e-27 96.3 0.0 1.7 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 CDS30072.1 - 1.5e-23 81.8 7.0 9.5e-06 25.4 0.0 6.8 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 CDS30072.1 - 5e-19 68.3 0.0 1.2e-13 51.0 0.0 2.4 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_3 PF13415.6 CDS30072.1 - 7.7e-12 45.2 11.5 0.0013 18.9 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS30072.1 - 2.9e-11 43.2 9.4 0.0019 18.2 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS30072.1 - 1.2e-07 31.6 8.5 2.2 8.4 0.0 6.3 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 CDS30072.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF1115 PF06544.12 CDS30074.2 - 6.2e-15 55.6 0.1 1e-14 54.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 CDS30074.2 - 3e-05 24.3 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-CSL PF05207.13 CDS30075.2 - 5.4e-21 74.1 1.0 5.4e-21 74.1 1.0 1.4 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_4 PF13717.6 CDS30075.2 - 0.059 13.3 0.5 0.099 12.6 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.12 CDS30075.2 - 0.13 10.8 1.0 0.27 9.7 1.0 1.6 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) AIRS_C PF02769.22 CDS30076.1 - 2.2e-21 76.6 0.0 3.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CDS30076.1 - 3.3e-09 37.3 0.4 6.3e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Y_phosphatase PF00102.27 CDS30077.2 - 1.5e-50 172.0 0.0 1.8e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDS30077.2 - 0.003 17.4 0.0 0.0079 16.0 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SUI1 PF01253.22 CDS30077.2 - 0.051 14.1 0.0 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor SUI1 Y_phosphatase3 PF13350.6 CDS30077.2 - 0.19 11.6 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 CDS30079.1 - 1.1e-107 360.1 0.0 1.5e-107 359.6 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 CDS30079.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDS30079.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Siva PF05458.12 CDS30079.1 - 1.2 8.8 6.2 2.1 8.0 6.2 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE PF01363.21 CDS30079.1 - 1.7 8.9 6.3 1.4 9.1 4.3 1.9 2 0 0 2 2 2 0 FYVE zinc finger Ank_2 PF12796.7 CDS30080.1 - 2.9e-19 69.4 5.4 3.4e-10 40.4 0.2 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30080.1 - 2e-12 47.3 1.4 4.5e-07 30.3 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS30080.1 - 1.7e-06 28.2 2.7 0.12 12.9 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDS30080.1 - 5.5e-06 26.3 5.3 4.8 8.1 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CDS30080.1 - 6.5e-06 26.3 0.7 0.0031 17.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Transposase_1 PF01359.18 CDS30081.1 - 6.3e-07 29.1 0.1 1.1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Transposase (partial DDE domain) WD40 PF00400.32 CDS30082.2 - 2.7e-07 31.2 2.1 0.43 11.5 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat NOA36 PF06524.12 CDS30082.2 - 1.6 8.0 9.7 4.4 6.5 9.7 1.7 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 CDS30082.2 - 2.3 8.6 7.3 7.3 7.0 7.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Yip1 PF04893.17 CDS30084.1 - 1.4e-09 37.9 9.1 1.4e-09 37.9 9.1 1.4 1 1 0 1 1 1 1 Yip1 domain Lysis_col PF02402.16 CDS30084.1 - 0.049 13.3 1.0 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Lysis protein LRR_8 PF13855.6 CDS30085.1 - 3.9e-13 48.9 16.0 1.6e-08 34.2 3.8 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CDS30085.1 - 5.5e-12 45.7 12.9 0.0005 20.4 2.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 CDS30085.1 - 9.7e-08 32.5 0.0 2.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS30085.1 - 9e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS30085.1 - 2e-05 24.8 0.0 7.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain LRR_9 PF14580.6 CDS30085.1 - 5.3e-05 22.8 1.0 0.00068 19.2 0.7 2.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CDS30085.1 - 0.00013 22.0 15.6 0.32 11.7 0.1 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat ig PF00047.25 CDS30085.1 - 0.0018 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_5 PF16681.5 CDS30085.1 - 0.0055 17.1 0.1 0.062 13.7 0.0 2.7 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 CDS30085.1 - 0.0088 16.2 0.0 0.064 13.4 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 CDS30085.1 - 0.032 14.3 5.3 0.95 9.7 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat PhoLip_ATPase_C PF16212.5 CDS30087.1 - 5.3e-81 272.0 21.6 5.3e-81 272.0 21.6 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDS30087.1 - 1.7e-24 85.2 4.3 6.2e-24 83.5 4.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CDS30087.1 - 5.1e-12 45.7 0.0 2.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDS30087.1 - 5.1e-10 40.0 0.8 0.0015 18.9 0.0 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDS30087.1 - 3.2e-09 36.6 0.1 3.2e-09 36.6 0.1 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDS30087.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAT_KAT11 PF08214.11 CDS30088.1 - 3e-28 99.1 1.4 2.2e-25 89.7 0.1 2.2 1 1 1 2 2 2 2 Histone acetylation protein Cation_ATPase_C PF00689.21 CDS30090.2 - 1.3e-32 112.9 4.1 1.3e-32 112.9 4.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDS30090.2 - 2.1e-32 112.1 2.2 1.3e-25 90.0 0.1 3.2 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 CDS30090.2 - 4.4e-16 59.8 0.1 4.6e-15 56.5 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDS30090.2 - 9.9e-15 54.4 0.0 3e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDS30090.2 - 4.4e-14 51.9 0.0 1.3e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDS30090.2 - 6.8e-07 29.3 4.4 1.6e-05 24.8 0.1 3.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 CDS30090.2 - 0.00031 21.1 2.3 0.001 19.5 2.3 1.9 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal DUF2976 PF11190.8 CDS30090.2 - 0.33 10.8 12.1 1.1 9.1 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) MnhB PF04039.13 CDS30090.2 - 9.2 6.6 7.5 4.5 7.6 0.0 3.3 3 1 1 4 4 3 0 Domain related to MnhB subunit of Na+/H+ antiporter RT_RNaseH PF17917.1 CDS30091.1 - 1.3e-21 76.9 0.0 2.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDS30091.1 - 3.1e-20 72.1 0.2 7.3e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MAP65_ASE1 PF03999.12 CDS30091.1 - 4.5e-08 32.3 6.9 4.5e-08 32.3 6.9 3.8 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) KLRAQ PF10205.9 CDS30091.1 - 0.028 14.7 2.6 0.035 14.3 0.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein LRR_8 PF13855.6 CDS30092.1 - 4e-16 58.5 11.3 5.4e-10 38.9 2.7 2.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 CDS30092.1 - 2.2e-08 34.1 0.0 0.0085 16.0 0.0 2.3 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDS30092.1 - 0.016 15.6 14.1 0.25 11.8 0.4 4.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS30092.1 - 5.6 7.9 7.7 1.3e+02 3.8 0.3 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat APG6_N PF17675.1 CDS30093.1 - 0.13 12.8 12.2 0.65 10.5 4.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Fungal_trans_2 PF11951.8 CDS30093.1 - 0.14 10.9 1.2 0.12 11.2 0.1 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF4844 PF16133.5 CDS30093.1 - 1.6 9.3 8.4 0.21 12.1 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4844) 2-Hacid_dh_C PF02826.19 CDS30094.1 - 3.6e-49 166.5 0.0 6.9e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDS30094.1 - 9.4e-27 93.3 0.0 9.3e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDS30094.1 - 9.9e-05 22.6 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CDS30094.1 - 0.14 12.2 0.3 8.1 6.5 0.1 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TFIIA PF03153.13 CDS30094.1 - 3.4 7.5 16.3 5.1 7.0 16.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CDS30094.1 - 9.3 4.8 18.9 13 4.3 18.9 1.1 1 0 0 1 1 1 0 Hamartin protein Tubulin PF00091.25 CDS30095.1 - 1.6e-63 214.5 0.0 2.2e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS30095.1 - 1.1e-34 119.3 0.2 1.6e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS30095.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS30095.1 - 0.0056 15.9 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin like TPR_12 PF13424.6 CDS30095.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Membr_traf_MHD PF10540.9 CDS30096.1 - 3.8e-43 147.2 3.8 1.4e-42 145.4 3.8 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CDS30096.1 - 4.7e-39 132.8 0.1 8.6e-27 93.4 0.2 3.1 2 0 0 2 2 2 2 C2 domain DUF1041 PF06292.17 CDS30096.1 - 4e-30 104.3 0.2 4e-30 104.3 0.2 3.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.22 CDS30096.1 - 2.7e-11 43.2 6.3 6.1e-11 42.0 6.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Med25_VWA PF11265.8 CDS30100.2 - 0.00015 21.7 0.0 0.00056 19.8 0.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A WD40 PF00400.32 CDS30101.1 - 3.2e-41 138.5 6.4 3e-09 37.4 0.7 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS30101.1 - 1.9e-17 63.3 0.2 0.00024 21.4 0.0 5.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CDS30101.1 - 1.8e-13 49.8 0.2 3.5e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CDS30101.1 - 6.4e-11 41.8 0.1 0.0067 15.4 0.0 4.5 3 1 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDS30101.1 - 6.4e-08 31.7 0.0 0.023 13.3 0.0 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDS30101.1 - 0.0028 16.5 0.0 1.8 7.2 0.0 3.7 1 1 2 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 CDS30101.1 - 0.023 14.0 0.0 0.097 12.0 0.0 1.9 1 1 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 CDS30101.1 - 0.3 11.6 3.0 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain UFC1 PF08694.11 CDS30102.2 - 4.8e-83 276.4 0.2 7.2e-83 275.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Zip PF02535.22 CDS30102.2 - 1.4e-30 106.7 13.2 1.7e-28 99.8 5.3 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter RWD PF05773.22 CDS30102.2 - 0.034 14.4 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.22 CDS30103.2 - 2.9e-11 43.0 0.1 1.7e-06 27.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS30103.2 - 0.0037 16.9 0.0 0.0057 16.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS30103.2 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif HAT_KAT11 PF08214.11 CDS30104.2 - 8.6e-61 206.2 0.9 8.6e-61 206.2 0.9 2.6 2 1 0 2 2 2 1 Histone acetylation protein KIX PF02172.16 CDS30104.2 - 2.2e-22 79.1 0.3 8e-22 77.3 0.3 2.0 1 0 0 1 1 1 1 KIX domain zf-TAZ PF02135.16 CDS30104.2 - 5.5e-22 78.0 54.8 6.7e-16 58.5 24.9 4.4 4 0 0 4 4 4 2 TAZ zinc finger Bromodomain PF00439.25 CDS30104.2 - 8.8e-22 77.0 2.4 2.3e-21 75.6 0.1 2.7 3 0 0 3 3 3 1 Bromodomain DUF902 PF06001.13 CDS30104.2 - 1.1e-14 54.6 9.1 1.1e-14 54.6 9.1 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) ZZ PF00569.17 CDS30104.2 - 6.5e-11 41.9 10.3 6.5e-11 41.9 10.3 3.0 3 0 0 3 3 3 1 Zinc finger, ZZ type KIX_2 PF16987.5 CDS30104.2 - 1.7e-06 27.9 0.1 6.2e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 KIX domain Aspzincin_M35 PF14521.6 CDS30104.2 - 0.018 15.6 2.3 0.1 13.2 2.3 2.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Pkinase PF00069.25 CDS30105.2 - 3e-52 177.6 0.0 4.9e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30105.2 - 4.6e-52 176.9 0.0 7.6e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RBD PF02196.15 CDS30105.2 - 5e-15 55.3 0.0 1.6e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.22 CDS30105.2 - 1.2e-07 31.4 7.0 3.1e-07 30.2 7.0 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 CDS30105.2 - 0.0007 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.11 CDS30105.2 - 0.0045 17.3 4.7 0.02 15.2 4.7 2.2 1 0 0 1 1 1 1 RING-like domain Pkinase_fungal PF17667.1 CDS30105.2 - 0.019 13.8 0.0 0.084 11.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CDS30105.2 - 0.087 12.2 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Histone_HNS PF00816.21 CDS30105.2 - 0.13 13.0 1.5 0.3 11.9 0.0 2.3 2 0 0 2 2 2 0 H-NS histone family PHD PF00628.29 CDS30105.2 - 0.31 11.0 3.0 0.82 9.6 3.0 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 CDS30105.2 - 1.2 9.0 4.6 3.2 7.7 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) His_Phos_2 PF00328.22 CDS30106.1 - 5.5e-13 49.0 0.0 2.6e-11 43.5 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FERM_C PF09380.10 CDS30107.2 - 2e-19 69.8 0.0 4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDS30107.2 - 3.6e-14 53.2 0.1 5.8e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 FERM central domain IBR PF01485.21 CDS30108.1 - 1.1e-11 44.8 34.7 2.3e-07 30.9 9.9 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CDS30108.1 - 0.0016 18.2 1.0 0.0016 18.2 1.0 4.7 3 3 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS30108.1 - 0.016 15.1 2.6 0.016 15.1 2.6 4.8 3 3 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF3624 PF12292.8 CDS30109.1 - 0.038 14.4 0.3 3.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) PH PF00169.29 CDS30112.1 - 0.00019 21.9 0.1 0.0034 17.9 0.1 2.7 1 1 0 2 2 2 1 PH domain ATP-synt_C PF00137.21 CDS30113.1 - 1.4e-10 41.4 12.5 2.3e-10 40.7 12.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Proteasome PF00227.26 CDS30114.1 - 2e-31 109.0 0.0 2.3e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Thaumatin PF00314.17 CDS30114.1 - 0.02 14.5 0.6 0.03 13.9 0.6 1.2 1 0 0 1 1 1 0 Thaumatin family Tetraspanin PF00335.20 CDS30115.1 - 6.9e-36 124.1 14.5 8.4e-36 123.8 14.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 CDS30115.1 - 0.11 12.3 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SIR2 PF02146.17 CDS30116.1 - 8.9e-55 185.3 0.0 1.1e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SIR2 PF02146.17 CDS30117.1 - 1.8e-53 181.1 0.0 2.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CUT PF02376.15 CDS30118.1 - 4.3e-32 110.1 0.2 8e-32 109.2 0.2 1.4 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CDS30118.1 - 4e-10 39.4 1.0 4e-10 39.4 1.0 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CDS30118.1 - 0.00056 19.8 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain HSP70 PF00012.20 CDS30120.1 - 2.9e-256 851.4 10.9 3.3e-256 851.2 10.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDS30120.1 - 1e-12 47.6 1.0 2e-12 46.6 0.2 1.8 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CDS30120.1 - 0.0045 16.7 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CDS30120.1 - 0.038 14.4 2.4 0.11 13.0 0.0 2.8 2 2 0 2 2 2 0 Cell division protein FtsA Phage_Gp23 PF10669.9 CDS30120.1 - 0.18 12.2 4.9 0.41 11.0 4.9 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Ndr PF03096.14 CDS30121.1 - 6.9e-65 218.6 0.0 8.8e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 CDS30121.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_34 PF11312.8 CDS30121.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase HTH_48 PF17906.1 CDS30122.1 - 6.2e-17 61.5 0.0 7.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF4817 PF16087.5 CDS30122.1 - 0.054 13.3 0.1 3.7 7.4 0.2 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain (DUF4817) CopK PF11525.8 CDS30122.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Copper resistance protein K NTF2 PF02136.20 CDS30123.1 - 2e-12 47.7 0.2 3.2e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 CDS30123.1 - 0.0066 17.1 0.0 0.015 15.9 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain cNMP_binding PF00027.29 CDS30126.2 - 6.5e-20 71.0 0.0 1.9e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CDS30126.2 - 5.5e-16 58.5 1.2 8.2e-16 58.0 1.2 1.2 1 0 0 1 1 1 1 Ion transport protein zf-C2H2 PF00096.26 CDS30126.2 - 1e-11 44.6 27.4 0.0041 17.5 0.1 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30126.2 - 2.7e-11 43.3 31.4 0.022 15.6 0.4 6.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS30126.2 - 6.7e-09 35.8 25.0 0.00097 19.5 0.5 5.3 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 CDS30126.2 - 0.00086 19.6 3.5 0.00086 19.6 3.5 3.4 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 CDS30126.2 - 0.0099 15.5 15.1 6.2 6.5 0.7 4.4 4 0 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain DUF4764 PF15961.5 CDS30126.2 - 0.023 13.4 5.8 4.2 5.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4764) Ion_trans_2 PF07885.16 CDS30126.2 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Ion channel zf-H2C2_5 PF13909.6 CDS30126.2 - 0.21 11.4 0.1 0.21 11.4 0.1 5.1 5 1 0 5 5 4 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDS30126.2 - 0.23 11.8 15.3 0.055 13.8 2.8 3.6 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding NOA36 PF06524.12 CDS30126.2 - 0.24 10.7 8.4 0.39 10.0 7.5 1.7 1 1 0 1 1 1 0 NOA36 protein zf-C2H2_11 PF16622.5 CDS30126.2 - 0.26 11.1 20.0 2.5 7.9 0.0 5.4 5 0 0 5 5 5 0 zinc-finger C2H2-type OrsD PF12013.8 CDS30126.2 - 0.77 10.2 9.6 3.2 8.2 5.9 2.6 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-ACC PF17848.1 CDS30126.2 - 0.81 9.8 5.3 22 5.2 0.1 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_3rep PF18868.1 CDS30126.2 - 1.2 9.8 16.2 9.2 7.0 1.6 4.6 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 CDS30126.2 - 3.4 8.2 20.7 2.7 8.5 1.8 4.6 3 1 2 5 5 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CDS30128.1 - 1.1e-08 35.1 23.4 6e-06 26.5 0.3 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30128.1 - 1.2e-05 25.5 36.4 0.00017 21.8 2.0 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CDS30128.1 - 0.1 13.0 7.9 0.28 11.7 0.9 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_4 PF07975.12 CDS30128.1 - 0.13 12.5 4.8 6.5 7.1 0.0 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 CDS30128.1 - 0.28 11.2 19.5 0.11 12.5 2.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.22 CDS30128.1 - 3.2 8.0 11.0 38 4.6 0.3 3.1 2 1 1 3 3 3 0 LIM domain zf_C2H2_ZHX PF18387.1 CDS30128.1 - 3.5 7.3 12.6 0.4 10.4 0.7 3.5 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH_5 PF14279.6 CDS30128.1 - 5.2 7.0 8.0 19 5.2 1.6 3.1 3 0 0 3 3 3 0 HNH endonuclease ZZ PF00569.17 CDS30130.1 - 9.9e-05 22.1 8.9 0.00018 21.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 CDS30131.1 - 5.3e-15 53.8 5.3 0.0011 18.3 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 CDS30131.1 - 2.7e-12 45.6 5.7 0.0061 16.4 0.0 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CDS30131.1 - 1.2e-10 41.7 17.6 0.00011 22.5 6.0 4.3 1 1 4 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.6 CDS30131.1 - 3e-10 39.8 4.2 0.01 15.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS30131.1 - 9.6e-10 37.5 9.5 0.0017 17.8 0.1 5.1 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 CDS30131.1 - 2.9e-05 24.3 8.9 0.3 11.4 0.4 3.5 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region SAM_1 PF00536.30 CDS30132.1 - 3.4e-25 88.2 0.4 8.4e-10 38.9 0.1 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS30132.1 - 1.4e-19 69.9 0.1 5.2e-06 26.5 0.0 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) Val_tRNA-synt_C PF10458.9 CDS30132.1 - 1.7 9.0 10.0 15 6.0 0.1 5.4 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Peptidase_M24 PF00557.24 CDS30134.1 - 9.8e-17 61.3 0.1 2.3e-16 60.1 0.1 1.5 1 1 1 2 2 2 1 Metallopeptidase family M24 MFS_1 PF07690.16 CDS30135.1 - 2.4e-17 62.9 42.5 3.8e-16 59.0 20.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS30135.1 - 2.6e-17 62.8 18.1 2.4e-13 49.8 5.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter zf-RING_UBOX PF13445.6 CDS30135.1 - 7.7e-05 22.6 8.2 0.00032 20.6 8.2 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS30135.1 - 0.00046 20.3 9.4 0.00046 20.3 9.4 2.9 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDS30135.1 - 0.00062 19.6 7.8 0.00062 19.6 7.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS30135.1 - 0.002 18.0 11.2 0.002 18.0 11.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS30135.1 - 0.0058 16.4 10.8 0.0058 16.4 10.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS30135.1 - 0.0059 16.4 9.5 0.02 14.7 9.5 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MFS_2 PF13347.6 CDS30135.1 - 0.014 13.9 20.3 0.0062 15.1 3.7 2.8 3 1 1 4 4 4 0 MFS/sugar transport protein zf-RING_10 PF16685.5 CDS30135.1 - 0.018 15.2 5.1 0.06 13.5 5.1 2.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF3945 PF13101.6 CDS30135.1 - 0.036 13.8 0.3 2.3 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3945) zf-RING_4 PF14570.6 CDS30135.1 - 3.6 7.5 7.4 18 5.2 7.4 2.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Presenilin PF01080.17 CDS30137.1 - 3.4e-145 483.8 3.2 4.4e-145 483.4 3.2 1.1 1 0 0 1 1 1 1 Presenilin Gemini_mov PF01708.16 CDS30137.1 - 4.2 7.2 5.8 2.3 8.0 0.6 3.0 2 1 1 3 3 3 0 Geminivirus putative movement protein PurA PF04845.13 CDS30138.1 - 1.2e-83 279.8 0.1 1.4e-83 279.5 0.1 1.1 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CDS30138.1 - 0.00012 22.2 7.3 0.38 10.9 0.3 3.7 2 2 1 3 3 3 3 Protein of unknown function (DUF3276) PurA PF04845.13 CDS30139.1 - 7.4e-50 169.3 1.9 8.7e-50 169.1 1.9 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CDS30139.1 - 3.8e-05 23.8 3.0 0.00076 19.6 0.1 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3276) PurA PF04845.13 CDS30140.1 - 1.7e-55 187.8 1.5 2e-55 187.5 1.5 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CDS30140.1 - 1.9e-09 37.7 6.2 0.00013 22.1 0.3 4.0 3 1 0 3 3 3 3 Protein of unknown function (DUF3276) Metallophos_2 PF12850.7 CDS30141.1 - 2.2e-19 70.3 0.0 2.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDS30141.1 - 0.00067 20.2 0.6 0.57 10.6 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase TFIID_20kDa PF03847.13 CDS30142.1 - 3.1e-15 56.4 0.3 4.8e-15 55.8 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CDS30142.1 - 6.1e-05 23.2 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone V-ATPase_C PF03223.15 CDS30142.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit C Histone PF00125.24 CDS30142.1 - 0.074 13.4 0.2 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DS PF01916.17 CDS30144.1 - 3.5e-120 400.6 0.0 1.1e-119 399.0 0.0 1.7 2 0 0 2 2 2 1 Deoxyhypusine synthase MRP-S35 PF10246.9 CDS30144.1 - 6.4e-28 96.8 0.0 2.5e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein MRP-S35 Cgr1 PF03879.14 CDS30144.1 - 8.7e-09 35.7 24.6 8.7e-09 35.7 24.6 1.9 2 0 0 2 2 2 1 Cgr1 family DNA_pol3_beta_2 PF02767.16 CDS30144.1 - 0.34 11.1 2.0 0.46 10.7 0.5 1.9 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain Usp PF00582.26 CDS30145.1 - 3.6e-08 34.0 0.0 1.9e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS30146.1 - 1.9e-23 83.6 0.0 2.3e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Beta-Casp PF10996.8 CDS30146.1 - 0.15 12.4 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 Beta-Casp domain TBCC_N PF16752.5 CDS30147.1 - 0.074 13.5 0.2 0.37 11.2 0.1 2.0 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Metallophos PF00149.28 CDS30149.1 - 6.6e-41 141.1 0.1 8.4e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDS30149.1 - 2.4e-21 75.9 2.2 2.4e-21 75.9 2.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain CBFD_NFYB_HMF PF00808.23 CDS30151.1 - 2.1e-14 53.6 0.2 1.2e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS30151.1 - 1.7e-06 28.4 0.4 6.1e-06 26.6 0.1 2.0 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CDS30151.1 - 0.067 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Smg8_Smg9 PF10220.9 CDS30151.1 - 0.22 9.8 3.5 0.27 9.5 3.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 CENP-X PF09415.10 CDS30151.1 - 0.25 11.7 3.3 0.33 11.3 0.0 2.5 3 1 0 3 3 3 0 CENP-S associating Centromere protein X RRN3 PF05327.11 CDS30151.1 - 5.4 5.4 7.1 6.2 5.2 7.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MRP-L51 PF10244.9 CDS30152.1 - 3.6e-29 100.8 0.3 5e-29 100.4 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit Aminotran_1_2 PF00155.21 CDS30154.1 - 3.5e-75 253.4 0.0 4e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-H2C2_2 PF13465.6 CDS30155.1 - 2.6e-07 30.8 5.3 3.8e-06 27.1 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30155.1 - 7e-06 26.2 11.5 0.035 14.6 5.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30155.1 - 0.0017 19.1 8.6 0.38 11.7 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 CDS30155.1 - 0.16 12.1 0.8 0.53 10.3 0.8 1.9 1 0 0 1 1 1 0 BED zinc finger PyrI_C PF02748.15 CDS30155.1 - 0.23 11.4 4.3 0.45 10.5 0.5 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.21 CDS30155.1 - 0.25 11.5 7.0 0.42 10.8 6.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 CDS30155.1 - 1.2 9.5 6.6 0.61 10.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Desulfoferrod_N PF06397.12 CDS30155.1 - 5.5 6.7 5.6 14 5.4 0.8 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Glypican PF01153.19 CDS30156.2 - 9.7e-31 107.2 0.5 1.1e-28 100.5 0.3 2.2 2 0 0 2 2 2 2 Glypican Pkinase PF00069.25 CDS30157.1 - 2.3e-63 214.1 0.0 5.8e-63 212.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30157.1 - 1.3e-34 119.6 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDS30157.1 - 1.9e-26 91.7 27.8 2.4e-13 49.7 9.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CDS30157.1 - 9.1e-13 48.4 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CDS30157.1 - 2.7e-06 28.0 0.8 7.1e-06 26.6 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDS30157.1 - 0.00049 19.5 0.0 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDS30157.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain zf-RING_9 PF13901.6 CDS30157.1 - 0.0018 18.3 18.5 0.049 13.6 6.6 2.4 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon C1_2 PF03107.16 CDS30157.1 - 0.01 16.1 16.9 0.51 10.7 6.7 2.6 2 0 0 2 2 2 0 C1 domain APH PF01636.23 CDS30157.1 - 0.016 15.1 0.5 0.22 11.4 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Zf_RING PF16744.5 CDS30157.1 - 0.25 11.5 17.1 0.18 11.9 5.6 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 CDS30157.1 - 4.4 7.3 21.4 8.1 6.4 5.8 2.5 2 0 0 2 2 2 0 PHD-finger FYVE_2 PF02318.16 CDS30157.1 - 4.6 7.5 13.5 11 6.3 3.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 CDS30157.1 - 4.7 7.2 17.2 5.9 6.9 3.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Kinesin PF00225.23 CDS30158.1 - 6.6e-32 110.7 0.0 1.4e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDS30158.1 - 1.3e-06 28.5 0.0 2.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Cnd1 PF12717.7 CDS30159.1 - 3.4e-46 157.2 2.5 7.4e-44 149.6 0.1 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CDS30159.1 - 1.2e-31 109.8 0.2 5.3e-31 107.7 0.2 2.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 CDS30159.1 - 2.1e-05 24.8 0.3 0.0016 18.8 0.1 3.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 CDS30159.1 - 4.5e-05 23.3 6.2 0.42 11.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 CDS30159.1 - 0.0084 15.3 6.6 0.021 14.0 0.1 3.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CDS30159.1 - 0.024 14.8 1.0 11 6.3 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CDS30159.1 - 0.041 14.4 0.1 1.2 9.7 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Med8 PF10232.9 CDS30160.1 - 2.1e-29 102.8 2.8 2.6e-29 102.5 2.8 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 XAP5 PF04921.14 CDS30161.1 - 7.8e-88 294.5 6.2 7.8e-88 294.5 6.2 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator MRC1 PF09444.10 CDS30161.1 - 0.026 15.1 0.7 0.026 15.1 0.7 3.0 2 1 0 3 3 3 0 MRC1-like domain ABC_membrane PF00664.23 CDS30162.2 - 4e-83 279.2 26.9 5.2e-54 183.8 11.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CDS30162.2 - 1.8e-70 235.8 0.1 8.3e-36 123.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDS30162.2 - 3.5e-13 49.5 5.2 0.00028 20.4 0.8 4.6 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CDS30162.2 - 1e-09 37.7 0.9 0.00018 20.5 0.0 3.1 4 0 0 4 4 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CDS30162.2 - 5.8e-09 36.3 0.2 0.0056 17.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDS30162.2 - 8.2e-09 36.1 0.1 0.0064 16.9 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CDS30162.2 - 2.3e-08 34.2 0.0 0.035 13.9 0.0 4.0 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDS30162.2 - 1.2e-07 31.3 0.1 0.0092 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 CDS30162.2 - 1.7e-06 28.5 0.6 1.5 9.2 0.0 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDS30162.2 - 3.8e-06 26.7 1.1 0.037 13.8 0.1 3.3 2 2 0 2 2 2 2 AAA domain Rad17 PF03215.15 CDS30162.2 - 1.1e-05 25.4 0.1 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain RsgA_GTPase PF03193.16 CDS30162.2 - 1.3e-05 25.2 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 CDS30162.2 - 6.1e-05 22.4 0.2 0.21 10.9 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_18 PF13238.6 CDS30162.2 - 7.3e-05 23.3 0.0 0.2 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CDS30162.2 - 9.3e-05 23.0 1.8 0.074 13.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 CDS30162.2 - 9.4e-05 22.3 0.0 0.051 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDS30162.2 - 0.00023 21.2 0.5 1.6 8.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDS30162.2 - 0.00028 20.5 0.0 0.68 9.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CDS30162.2 - 0.0004 20.6 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 CDS30162.2 - 0.001 19.3 5.1 1.3 9.3 0.4 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 CDS30162.2 - 0.0028 16.9 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_17 PF13207.6 CDS30162.2 - 0.0042 17.5 0.8 4.2 7.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CDS30162.2 - 0.0042 17.3 1.3 1.6 9.0 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CDS30162.2 - 0.0042 16.7 0.1 3.5 7.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDS30162.2 - 0.0088 16.4 0.1 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.29 CDS30162.2 - 0.0093 15.8 0.2 2 8.2 0.0 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Cytidylate_kin PF02224.18 CDS30162.2 - 0.0096 15.7 0.0 4.1 7.1 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase APS_kinase PF01583.20 CDS30162.2 - 0.012 15.5 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3987 PF13148.6 CDS30162.2 - 0.016 14.2 0.0 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 CDS30162.2 - 0.017 14.9 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDS30162.2 - 0.02 14.8 0.1 6 6.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 CDS30162.2 - 0.022 14.5 0.1 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CDS30162.2 - 0.023 13.9 0.0 8.2 5.5 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 CDS30162.2 - 0.061 13.1 0.1 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDS30162.2 - 0.099 12.7 0.0 4 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 CDS30162.2 - 0.1 12.7 0.3 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3147 PF11345.8 CDS30162.2 - 0.46 10.9 19.9 2.4 8.6 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) zf-C2H2_jaz PF12171.8 CDS30163.2 - 4.7e-08 33.1 4.2 7.3e-08 32.5 4.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS30163.2 - 9.5e-05 22.7 0.2 0.00013 22.3 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDS30163.2 - 0.00077 19.8 1.1 0.0012 19.1 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NOA36 PF06524.12 CDS30163.2 - 0.024 14.0 0.2 0.025 13.9 0.2 1.1 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_4 PF13894.6 CDS30163.2 - 0.038 14.8 1.0 0.069 14.0 1.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYST PF17772.1 CDS30163.2 - 0.072 12.7 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain zf-B_box PF00643.24 CDS30163.2 - 0.093 12.9 1.2 0.12 12.5 0.3 1.7 2 0 0 2 2 2 0 B-box zinc finger IBR PF01485.21 CDS30167.1 - 2.7e-11 43.5 27.6 2.1e-10 40.7 3.9 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 CDS30167.1 - 3.6e-09 36.9 0.0 7.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 CDS30167.1 - 0.00015 22.0 8.9 0.00015 22.0 8.9 4.2 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 CDS30167.1 - 0.00067 19.6 9.3 0.00067 19.6 9.3 5.0 4 2 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS30167.1 - 0.0095 15.9 4.6 0.0095 15.9 4.6 4.5 4 1 0 4 4 4 2 RING-type zinc-finger Prok-RING_4 PF14447.6 CDS30167.1 - 9.9 6.1 36.3 14 5.7 3.3 5.6 3 3 2 5 5 5 0 Prokaryotic RING finger family 4 EF-hand_1 PF00036.32 CDS30168.1 - 3.6e-37 123.1 10.8 7.1e-10 37.7 1.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS30168.1 - 2.6e-30 101.7 4.5 1.2e-07 31.0 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS30168.1 - 7.9e-29 99.3 11.6 9.6e-16 57.4 1.6 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.6 CDS30168.1 - 2e-28 98.7 9.5 6.9e-14 52.1 1.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS30168.1 - 7.5e-23 79.0 6.1 4.8e-05 22.7 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDS30168.1 - 2.4e-10 40.6 0.2 0.00012 22.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS30168.1 - 2.6e-09 37.4 3.2 0.001 19.3 0.3 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS30168.1 - 3.6e-09 36.5 1.7 0.0007 19.5 0.2 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CDS30168.1 - 0.00012 21.9 5.7 0.057 13.3 0.8 2.9 2 1 1 3 3 3 2 EF hand DUF1722 PF08349.11 CDS30168.1 - 0.00033 20.9 0.2 0.067 13.5 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1722) Dockerin_1 PF00404.18 CDS30168.1 - 0.0014 18.8 0.6 0.77 10.0 0.0 2.7 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 CDS30168.1 - 0.0027 18.6 0.3 0.93 10.4 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CDS30168.1 - 0.0039 17.1 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB OST-HTH PF12872.7 CDS30168.1 - 0.0042 16.9 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 OST-HTH/LOTUS domain SurA_N_3 PF13624.6 CDS30168.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 CDS30168.1 - 0.032 14.6 0.8 2.9 8.3 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 CDS30168.1 - 0.078 12.9 2.4 4.3 7.2 0.1 3.3 2 2 2 4 4 4 0 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CDS30168.1 - 0.49 10.7 2.8 13 6.1 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 DcpS_C PF11969.8 CDS30169.1 - 8.1e-20 71.4 0.0 1.8e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CDS30169.1 - 1.2e-14 55.0 0.0 2.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Gemin7 PF11095.8 CDS30170.1 - 8.6e-08 32.0 0.0 2.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Gem-associated protein 7 (Gemin7) TM2 PF05154.16 CDS30171.1 - 2.6e-11 43.7 8.2 2.6e-11 43.7 8.2 1.7 2 0 0 2 2 2 1 TM2 domain DWNN PF08783.11 CDS30172.1 - 4.6e-21 74.9 0.2 1e-20 73.7 0.2 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_3 PF13917.6 CDS30172.1 - 7.2e-06 25.9 0.2 2.1e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDS30172.1 - 9.4e-05 22.1 12.6 9.4e-05 22.1 12.6 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 CDS30172.1 - 0.00091 19.2 4.5 0.00091 19.2 4.5 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 CDS30172.1 - 0.42 10.5 22.8 0.023 14.6 15.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CDS30172.1 - 2 8.3 10.8 4.1 7.4 10.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Filamin PF00630.19 CDS30175.1 - 1.8e-07 31.9 0.1 3e-07 31.2 0.1 1.4 1 1 0 1 1 1 1 Filamin/ABP280 repeat HAGH_C PF16123.5 CDS30175.1 - 0.028 14.9 0.2 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Laminin_II PF06009.12 CDS30175.1 - 0.087 12.8 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Laminin Domain II YlqD PF11068.8 CDS30175.1 - 0.23 11.8 1.3 0.46 10.9 1.3 1.5 1 0 0 1 1 1 0 YlqD protein FGGY_C PF02782.16 CDS30176.1 - 5.5e-17 62.2 0.0 1.9e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CDS30176.1 - 1.1e-10 41.5 0.0 5.4e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain MFS_1 PF07690.16 CDS30179.1 - 3.3e-13 49.3 44.0 3.3e-13 49.3 44.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Adaptin_N PF01602.20 CDS30180.1 - 1.2e-88 298.0 4.6 1.6e-88 297.5 4.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CDS30180.1 - 5.3e-53 178.7 0.6 5.3e-53 178.7 0.6 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CDS30180.1 - 6.3e-48 162.0 0.0 1.7e-47 160.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 CDS30180.1 - 6.7e-09 36.0 0.4 6.7e-09 36.0 0.4 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDS30180.1 - 4.8e-08 32.6 0.2 0.018 15.3 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CDS30180.1 - 1e-06 29.0 1.2 0.037 14.4 0.0 4.7 3 1 2 5 5 5 2 HEAT repeats Ribosomal_60s PF00428.19 CDS30180.1 - 0.0037 17.8 0.2 0.017 15.7 0.0 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF5578 PF17741.1 CDS30180.1 - 0.0051 16.3 4.7 0.0083 15.6 0.6 2.7 2 1 1 3 3 3 2 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 CDS30180.1 - 0.017 15.6 0.0 5.4 7.6 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDS30180.1 - 0.026 15.1 1.4 20 5.8 0.0 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ribosomal_L1 PF00687.21 CDS30182.1 - 4.8e-37 127.7 1.0 8.7e-28 97.5 0.2 2.0 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family Beach PF02138.18 CDS30185.2 - 6.9e-54 183.1 0.0 8.9e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 CDS30187.1 - 2.8e-08 33.3 0.0 4.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) OCRE PF17780.1 CDS30188.1 - 8.3e-14 51.3 7.9 8.3e-14 51.3 7.9 1.7 2 0 0 2 2 2 1 OCRE domain UBX PF00789.20 CDS30189.1 - 9.6e-16 57.8 0.0 1.9e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 CDS30189.1 - 0.0058 16.5 0.3 0.048 13.6 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain RNHCP PF12647.7 CDS30189.1 - 0.025 14.6 0.6 0.049 13.6 0.6 1.5 1 0 0 1 1 1 0 RNHCP domain zf_UBZ PF18439.1 CDS30189.1 - 0.044 13.4 0.2 0.099 12.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 CDS30189.1 - 0.069 13.5 1.1 0.069 13.5 1.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3827 PF12877.7 CDS30189.1 - 0.24 9.8 6.9 0.29 9.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RR_TM4-6 PF06459.12 CDS30189.1 - 4 7.2 15.8 5.6 6.7 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 CDS30191.1 - 3.5e-68 225.4 6.1 1.7e-17 63.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS30191.1 - 3.2e-22 78.4 2.8 9.8e-05 22.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS30191.1 - 3.4e-08 33.3 0.3 0.32 11.0 0.1 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RL PF17797.1 CDS30191.1 - 5.3e-07 29.5 0.2 3.5 7.7 0.0 4.3 4 0 0 4 4 4 3 RL domain Nup35_RRM PF05172.13 CDS30191.1 - 2.8e-06 27.2 0.3 4.8 7.2 0.0 4.4 3 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS30191.1 - 0.00027 21.0 3.7 5.3 7.2 0.0 4.2 4 0 0 4 4 4 1 RNA binding motif DUF4651 PF15513.6 CDS30191.1 - 0.0016 18.2 0.0 5 7.0 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4651) DUF2817 PF10994.8 CDS30191.1 - 0.0047 16.4 1.3 0.17 11.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2817) OB_RNB PF08206.11 CDS30191.1 - 0.013 15.1 4.9 8.5 6.1 0.0 4.2 4 0 0 4 4 4 0 Ribonuclease B OB domain PhetRS_B1 PF18262.1 CDS30191.1 - 0.02 15.1 0.1 3.5 7.9 0.0 3.4 4 0 0 4 4 4 0 Phe-tRNA synthetase beta subunit B1 domain CSD PF00313.22 CDS30191.1 - 0.28 11.1 5.7 12 5.8 0.1 4.1 4 0 0 4 4 4 0 'Cold-shock' DNA-binding domain Ribosomal_L14 PF00238.19 CDS30191.1 - 0.31 11.1 5.1 3.6 7.7 0.7 2.9 3 1 1 4 4 4 0 Ribosomal protein L14p/L23e AGP PF06376.12 CDS30191.1 - 0.61 10.0 1.7 1.9 8.4 0.4 2.3 2 0 0 2 2 2 0 Arabinogalactan peptide Ephrin PF00812.17 CDS30192.1 - 0.00038 20.5 0.3 0.11 12.5 0.1 2.5 2 0 0 2 2 2 2 Ephrin p47_phox_C PF08944.11 CDS30192.1 - 0.14 11.6 3.3 0.44 10.0 1.6 2.4 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Glyco_hydro_47 PF01532.20 CDS30194.2 - 1.3e-114 383.7 0.0 2.5e-114 382.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 CDS30194.2 - 1.7e-07 31.1 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PA domain PDZ_6 PF17820.1 CDS30195.1 - 0.011 15.5 0.0 7.3 6.5 0.0 3.0 3 0 0 3 3 3 0 PDZ domain PDZ_2 PF13180.6 CDS30195.1 - 0.022 15.1 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain HEAT_EZ PF13513.6 CDS30196.1 - 6.1e-20 71.3 1.0 9.7e-11 41.9 0.0 6.7 7 0 0 7 7 6 2 HEAT-like repeat HEAT PF02985.22 CDS30196.1 - 4.8e-16 57.5 14.9 1.3e-06 28.1 0.0 8.0 10 0 0 10 10 8 3 HEAT repeat IBN_N PF03810.19 CDS30196.1 - 7e-12 45.1 0.3 1.4e-10 40.9 0.0 3.4 3 0 0 3 3 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CDS30196.1 - 2.4e-09 37.5 0.9 0.0009 19.6 0.0 7.1 5 3 3 8 8 8 2 HEAT repeats CLASP_N PF12348.8 CDS30196.1 - 4.1e-08 33.1 3.2 0.011 15.3 0.1 5.5 2 2 3 5 5 5 3 CLASP N terminal Adaptin_N PF01602.20 CDS30196.1 - 1.8e-06 26.8 7.9 0.015 13.9 0.9 3.9 3 1 0 4 4 4 3 Adaptin N terminal region DUF3385 PF11865.8 CDS30196.1 - 3.3e-06 27.1 2.3 5.3 6.9 0.1 5.2 4 1 2 6 6 6 3 Domain of unknown function (DUF3385) Arm PF00514.23 CDS30196.1 - 4.1e-05 23.5 16.1 0.13 12.3 0.0 6.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CDS30196.1 - 0.0017 18.4 4.4 0.28 11.2 0.0 4.7 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CDS30196.1 - 0.0031 16.8 2.2 0.25 10.5 0.0 4.5 4 2 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain RIX1 PF08167.12 CDS30196.1 - 0.088 12.5 4.3 17 5.1 0.2 4.4 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 CDS30196.1 - 0.13 12.3 4.5 1.8 8.6 0.2 4.5 4 1 1 5 5 5 0 Exportin 1-like protein DUF412 PF04217.13 CDS30196.1 - 0.31 10.9 3.4 0.53 10.2 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function, DUF412 zf-C2H2_11 PF16622.5 CDS30197.2 - 9.7e-05 22.0 14.9 0.0073 16.0 0.3 4.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CDS30197.2 - 0.00051 20.7 52.7 0.0073 17.1 0.5 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS30197.2 - 0.0038 17.5 23.9 0.2 12.0 0.4 4.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CDS30197.2 - 0.006 17.0 8.0 0.82 10.2 0.5 4.3 4 0 0 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CDS30197.2 - 0.0062 16.9 17.0 0.74 10.3 1.0 4.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDS30197.2 - 0.0064 16.9 41.9 0.13 12.8 0.5 6.7 7 0 0 7 7 7 3 Zinc finger, C2H2 type TerY_C PF15616.6 CDS30197.2 - 0.026 14.6 0.3 0.026 14.6 0.3 2.2 3 0 0 3 3 3 0 TerY-C metal binding domain zf-H2C2_2 PF13465.6 CDS30197.2 - 0.038 14.4 30.1 0.046 14.2 0.7 5.9 5 0 0 5 5 5 0 Zinc-finger double domain zf-Di19 PF05605.12 CDS30197.2 - 0.097 13.0 0.3 0.097 13.0 0.3 4.3 4 1 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDS30197.2 - 0.18 12.1 14.1 1.6 9.1 0.2 4.2 4 1 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CDS30197.2 - 0.67 10.3 17.2 3.3 8.1 5.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 CDS30197.2 - 0.72 10.5 14.1 0.83 10.3 0.3 4.5 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats Ras PF00071.22 CDS30198.1 - 1.8e-53 180.5 0.0 2e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30198.1 - 1.2e-20 73.9 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30198.1 - 1.1e-13 51.0 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS30198.1 - 2.7e-07 30.3 0.0 9.6e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS30198.1 - 4.4e-06 26.7 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDS30198.1 - 8.8e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDS30198.1 - 0.0008 19.3 0.9 0.0023 17.8 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 CDS30198.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 CDS30198.1 - 0.0035 16.7 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS30198.1 - 0.0077 15.7 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SepSecS PF05889.13 CDS30198.1 - 0.011 14.5 0.1 0.014 14.1 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CbiA PF01656.23 CDS30198.1 - 0.018 15.1 0.5 0.28 11.3 0.5 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sacchrp_dh_NADP PF03435.18 CDS30198.1 - 0.031 14.5 0.0 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FeoB_N PF02421.18 CDS30198.1 - 0.031 13.8 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B WW PF00397.26 CDS30199.2 - 3.6e-05 23.8 0.1 6.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 WW domain CNOT1_CAF1_bind PF16415.5 CDS30200.1 - 8.2e-44 149.7 1.6 9.1e-44 149.5 1.6 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain MIF4G PF02854.19 CDS30200.1 - 1.3e-05 25.0 0.1 2e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 MIF4G domain Xpo1 PF08389.12 CDS30200.1 - 0.024 14.7 1.5 0.48 10.5 0.8 2.6 2 2 1 3 3 3 0 Exportin 1-like protein RabGAP-TBC PF00566.18 CDS30201.1 - 1.3e-35 123.1 1.1 4.8e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Med20 PF08612.11 CDS30202.1 - 1.7e-14 53.8 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex zf-B_box PF00643.24 CDS30203.1 - 1.5e-11 44.3 17.4 1.5e-09 37.8 9.0 4.3 3 1 0 3 3 2 2 B-box zinc finger zf-RING_UBOX PF13445.6 CDS30203.1 - 9.7e-09 35.1 6.8 9.7e-09 35.1 6.8 3.0 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS30203.1 - 4.1e-07 29.8 11.0 4.1e-07 29.8 11.0 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDS30203.1 - 1.4e-06 28.3 9.0 1.4e-06 28.3 9.0 3.9 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDS30203.1 - 1.6e-05 25.2 8.7 1.6e-05 25.2 8.7 4.1 4 0 0 4 4 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS30203.1 - 0.0001 22.1 11.3 0.0001 22.1 11.3 3.8 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS30203.1 - 0.00015 21.5 6.8 0.00015 21.5 6.8 3.8 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS30203.1 - 0.00054 19.9 10.2 0.00054 19.9 10.2 3.8 4 0 0 4 4 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS30203.1 - 0.011 15.6 5.4 0.011 15.6 5.4 3.8 3 1 0 3 3 2 0 Prokaryotic RING finger family 4 ATP-synt_B PF00430.18 CDS30203.1 - 0.045 13.8 2.1 0.092 12.8 2.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF948 PF06103.11 CDS30203.1 - 0.38 11.1 1.4 1 9.7 0.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Siva PF05458.12 CDS30203.1 - 8.5 6.0 15.3 0.98 9.1 1.1 3.0 3 0 0 3 3 3 0 Cd27 binding protein (Siva) Homeodomain PF00046.29 CDS30204.1 - 1.5e-21 76.0 4.3 3.4e-21 74.8 4.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS30204.1 - 0.0053 16.6 1.3 0.0096 15.8 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain CsgF PF10614.9 CDS30205.1 - 0.00028 21.1 3.9 1.8 8.8 0.0 3.5 3 0 0 3 3 3 2 Type VIII secretion system (T8SS), CsgF protein SmAKAP PF15127.6 CDS30205.1 - 0.00055 21.1 2.8 0.36 12.1 0.0 4.0 1 1 1 3 3 3 1 Small membrane A-kinase anchor protein FlaF PF07309.11 CDS30205.1 - 0.075 13.0 1.4 0.24 11.4 1.4 1.8 1 0 0 1 1 1 0 Flagellar protein FlaF FF PF01846.19 CDS30206.1 - 1.2e-32 111.8 19.7 2.3e-07 30.9 0.0 6.9 6 0 0 6 6 6 5 FF domain WW PF00397.26 CDS30206.1 - 4.8e-17 61.8 18.1 5.6e-09 35.9 2.1 2.7 2 0 0 2 2 2 2 WW domain FHA PF00498.26 CDS30206.1 - 1.6e-15 57.2 0.1 3.9e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDS30206.1 - 0.0022 18.3 0.0 0.008 16.5 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Laminin_II PF06009.12 CDS30206.1 - 0.013 15.5 20.3 0.17 11.9 2.5 3.8 3 0 0 3 3 3 0 Laminin Domain II WW_1 PF18507.1 CDS30206.1 - 0.023 14.4 0.6 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 WW domain SLATT_1 PF18181.1 CDS30206.1 - 0.85 9.6 4.6 3.1 7.8 0.1 3.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 TSC22 PF01166.18 CDS30206.1 - 4.1 7.8 20.6 1.8 8.9 0.1 5.8 4 2 0 4 4 4 0 TSC-22/dip/bun family Metal_resist PF13801.6 CDS30206.1 - 7.2 6.8 11.3 0.33 11.1 1.3 3.8 4 0 0 4 4 4 0 Heavy-metal resistance G_glu_transpept PF01019.21 CDS30207.1 - 1.3e-140 469.6 0.0 1.5e-140 469.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Importin_rep PF18773.1 CDS30208.1 - 0.059 13.1 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Importin 13 repeat zf-CCHC_3 PF13917.6 CDS30209.2 - 1.4e-15 57.0 6.1 2.9e-15 55.9 5.6 1.8 2 0 0 2 2 2 1 Zinc knuckle Zn_ribbon_2 PF12674.7 CDS30209.2 - 0.0097 16.5 0.6 0.025 15.2 0.6 1.7 1 0 0 1 1 1 1 Putative zinc ribbon domain TAP_C PF03943.13 CDS30209.2 - 0.14 11.8 0.5 0.29 10.8 0.5 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Smg8_Smg9 PF10220.9 CDS30209.2 - 4.8 5.4 10.8 6.6 4.9 10.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 FHA PF00498.26 CDS30211.1 - 1e-13 51.4 0.6 1.6e-13 50.8 0.3 1.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDS30211.1 - 0.0032 17.7 0.0 0.0051 17.1 0.0 1.4 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CGI-121 PF08617.10 CDS30212.1 - 1.5e-23 83.7 0.0 1.3e-22 80.7 0.0 2.5 3 0 0 3 3 3 1 Kinase binding protein CGI-121 RRM_1 PF00076.22 CDS30212.1 - 7e-20 70.6 0.1 2.2e-06 27.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS30212.1 - 0.0023 17.7 0.1 0.022 14.6 0.1 2.8 2 1 0 2 2 2 1 Occluded RNA-recognition motif Med13_C PF06333.12 CDS30213.1 - 2.1e-67 227.8 0.0 1.3e-37 129.8 0.0 3.3 3 1 0 3 3 3 2 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 CDS30213.1 - 2.9e-29 102.5 0.8 5e-29 101.7 0.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 CDS30213.1 - 1.6e-14 54.3 0.0 6e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 MID domain of medPIWI CH PF00307.31 CDS30214.1 - 3.3e-23 81.9 0.3 4.1e-12 46.2 0.2 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS30214.1 - 1.2e-05 25.1 0.1 0.00052 19.8 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 CDS30214.1 - 0.00073 19.6 0.0 0.22 11.7 0.0 3.0 3 0 0 3 3 3 1 CH-like domain in sperm protein WD40 PF00400.32 CDS30215.1 - 1.1e-21 76.7 12.5 6.6e-05 23.6 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDS30215.1 - 0.002 17.1 0.0 0.038 13.0 0.1 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CDS30215.1 - 0.18 11.9 0.1 26 4.9 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MA3 PF02847.17 CDS30216.1 - 0.00011 22.2 0.7 0.001 19.1 0.1 2.8 3 0 0 3 3 3 1 MA3 domain G_glu_transpept PF01019.21 CDS30217.1 - 8.6e-61 206.2 0.0 1.2e-60 205.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RRM_1 PF00076.22 CDS30218.1 - 2.9e-10 39.8 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 CDS30218.1 - 0.27 11.9 7.8 0.42 11.3 7.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family RhlB PF12300.8 CDS30218.1 - 0.38 10.9 10.7 0.048 13.8 6.8 1.5 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB DUF3338 PF11819.8 CDS30219.1 - 0.00024 21.1 1.2 0.00024 21.1 1.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3338) zf-C3HC4 PF00097.25 CDS30220.1 - 3.2e-09 36.5 6.1 3.2e-09 36.5 6.1 2.2 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS30220.1 - 3.4e-09 36.4 7.0 3.4e-09 36.4 7.0 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS30220.1 - 6.5e-09 35.5 3.5 1.7e-08 34.2 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS30220.1 - 1.1e-08 35.2 7.0 1.1e-08 35.2 7.0 2.7 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDS30220.1 - 3.2e-06 26.9 6.2 1.7e-05 24.6 6.6 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDS30220.1 - 1.9e-05 24.9 6.8 1.9e-05 24.9 6.8 2.8 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS30220.1 - 2.8e-05 24.0 4.1 2.8e-05 24.0 4.1 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS30220.1 - 5.7e-05 23.1 6.9 5.7e-05 23.1 6.9 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS30220.1 - 0.011 15.9 6.7 0.27 11.4 7.4 3.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 CDS30220.1 - 0.015 15.4 3.0 0.035 14.2 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Endonuclease_7 PF02945.15 CDS30220.1 - 0.038 13.9 0.6 0.038 13.9 0.6 2.3 2 1 0 2 2 1 0 Recombination endonuclease VII Rad50_zn_hook PF04423.14 CDS30220.1 - 0.04 13.7 2.0 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1980 PF09323.10 CDS30220.1 - 0.15 12.0 0.2 0.41 10.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) UBZ_FAAP20 PF15750.5 CDS30220.1 - 0.25 11.3 3.3 2.3 8.2 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_6 PF14835.6 CDS30220.1 - 0.34 10.8 5.9 0.36 10.7 2.8 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CDS30220.1 - 1.3 8.9 11.8 6.4 6.7 9.5 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CDS30220.1 - 2.4 8.1 8.3 4.7 7.2 6.2 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CDS30220.1 - 2.6 7.8 8.7 20 5.0 9.0 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf_ZIC PF18366.1 CDS30221.1 - 3e-08 33.6 0.8 3e-08 33.6 0.8 3.1 3 1 0 3 3 3 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 CDS30221.1 - 4.3e-07 30.1 1.4 4.3e-07 30.1 1.4 4.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30221.1 - 0.00049 20.4 23.7 0.0019 18.6 1.6 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30221.1 - 0.0048 17.6 2.8 0.08 13.8 1.6 4.5 5 0 0 5 5 5 2 C2H2-type zinc finger Glycoprotein PF03409.15 CDS30221.1 - 0.0051 15.7 2.5 0.007 15.3 2.5 1.1 1 0 0 1 1 1 1 Transmembrane glycoprotein FOXP-CC PF16159.5 CDS30221.1 - 0.038 14.6 7.5 3.3 8.4 0.3 3.6 1 1 2 3 3 3 0 FOXP coiled-coil domain SVWC PF15430.6 CDS30221.1 - 0.046 14.0 1.5 0.84 10.0 0.5 2.5 2 0 0 2 2 2 0 Single domain von Willebrand factor type C DUF2158 PF09926.9 CDS30221.1 - 0.19 11.5 1.7 3.6 7.4 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2158) Myc_N PF01056.18 CDS30222.1 - 0.058 13.3 0.3 0.078 12.9 0.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Med3 PF11593.8 CDS30222.1 - 0.13 11.4 6.7 0.16 11.1 6.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.11 CDS30222.1 - 3.5 8.1 8.8 4.4 7.8 1.4 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HLH PF00010.26 CDS30223.2 - 8e-12 44.9 0.5 4.4e-11 42.6 0.9 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LisH PF08513.11 CDS30223.2 - 8e-05 22.4 0.0 0.00019 21.2 0.0 1.7 1 0 0 1 1 1 1 LisH VPS13_mid_rpt PF16910.5 CDS30225.2 - 6.5e-69 231.9 8.1 6e-56 189.5 0.1 6.2 7 0 0 7 7 7 3 Repeating coiled region of VPS13 VPS13_C PF16909.5 CDS30225.2 - 8.5e-59 198.3 6.8 4.2e-55 186.3 0.1 3.2 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CDS30225.2 - 4.7e-56 190.2 3.0 1.8e-55 188.3 1.5 2.8 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDS30225.2 - 3.4e-34 117.4 0.3 1.5e-33 115.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CDS30225.2 - 5.1e-32 111.3 0.0 1e-29 103.7 0.0 2.6 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CDS30225.2 - 6.1e-06 26.5 0.0 2.5e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain RasGAP PF00616.19 CDS30227.1 - 1.8e-21 76.8 0.0 4.7e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CDS30227.1 - 0.0002 21.6 0.0 0.00096 19.4 0.0 2.2 2 1 0 2 2 2 1 C2 domain PH PF00169.29 CDS30228.2 - 0.047 14.2 0.1 0.17 12.4 0.0 2.0 2 1 0 2 2 2 0 PH domain DUF1758 PF05585.12 CDS30228.2 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2_5 PF13909.6 CDS30229.1 - 3.9e-05 23.3 0.2 3.9e-05 23.3 0.2 3.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDS30229.1 - 0.0063 16.9 14.0 0.64 10.6 0.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type HD_assoc PF13286.6 CDS30229.1 - 0.015 15.8 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain zf-C2H2_4 PF13894.6 CDS30229.1 - 0.093 13.6 15.7 10 7.3 1.4 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS30229.1 - 0.19 12.2 0.4 0.19 12.2 0.4 4.1 6 0 0 6 6 6 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CDS30229.1 - 0.37 10.5 10.9 4.6 6.9 0.1 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 CDS30229.1 - 1.1 9.2 7.6 3.8 7.4 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) SRP54 PF00448.22 CDS30231.2 - 1.5e-49 168.3 0.7 2.3e-48 164.4 0.7 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CDS30231.2 - 1.1e-07 32.0 0.0 3.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP-alpha_N PF04086.13 CDS30231.2 - 4.6e-05 23.5 4.4 4.6e-05 23.5 4.4 1.6 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.23 CDS30231.2 - 8.5e-05 22.6 0.1 0.0011 19.1 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CDS30231.2 - 0.00014 21.0 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CDS30231.2 - 0.0011 19.3 0.0 0.0058 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDS30231.2 - 0.0011 19.2 0.1 0.074 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CDS30231.2 - 0.0027 17.6 0.1 0.018 15.0 0.1 2.2 1 1 0 1 1 1 1 NTPase ArsA_ATPase PF02374.15 CDS30231.2 - 0.0038 16.5 0.2 0.017 14.3 0.1 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 CDS30231.2 - 0.014 15.3 0.1 0.057 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CDS30231.2 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CDS30231.2 - 0.042 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PfkB PF00294.24 CDS30231.2 - 0.082 12.2 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 pfkB family carbohydrate kinase ParA PF10609.9 CDS30231.2 - 0.093 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase MMR_HSR1 PF01926.23 CDS30231.2 - 0.094 12.8 0.7 1.2 9.3 0.7 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDS30231.2 - 0.12 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 CDS30231.2 - 0.87 8.9 9.1 0.057 12.8 2.2 1.8 1 1 0 2 2 2 0 SDA1 Cactin_mid PF10312.9 CDS30233.2 - 7e-58 195.6 1.1 1.7e-57 194.4 1.1 1.7 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 CDS30233.2 - 1.4e-54 183.4 8.6 2.5e-54 182.5 8.6 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Tim17 PF02466.19 CDS30233.2 - 1.9e-22 79.8 6.9 3.3e-22 79.0 6.9 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5-FTHF_cyc-lig PF01812.20 CDS30237.2 - 1.4e-27 96.8 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Phage_rep_org_N PF09681.10 CDS30239.2 - 0.063 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Sec8_exocyst PF04048.14 CDS30240.2 - 5.5e-07 29.6 1.0 6.6e-07 29.3 1.0 1.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Terminase_2 PF03592.16 CDS30240.2 - 0.028 14.9 0.2 0.033 14.7 0.2 1.2 1 0 0 1 1 1 0 Terminase small subunit Zw10 PF06248.13 CDS30240.2 - 0.049 12.2 2.9 0.063 11.8 2.9 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 MIG-14_Wnt-bd PF06664.12 CDS30241.2 - 3.3e-80 269.4 11.6 4.4e-80 269.0 11.6 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Potass_KdpF PF09604.10 CDS30241.2 - 1.3 9.1 4.4 4.5 7.4 4.4 2.0 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) PalH PF08733.10 CDS30241.2 - 2.6 7.0 7.5 7.9 5.4 6.9 2.2 1 1 0 1 1 1 0 PalH/RIM21 FERM_C PF09380.10 CDS30243.1 - 1.3e-21 76.8 0.2 3.3e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.29 CDS30243.1 - 2.9e-16 59.9 0.1 3.6e-08 33.9 0.0 2.9 2 0 0 2 2 2 2 PH domain FERM_M PF00373.18 CDS30243.1 - 9.2e-15 55.1 0.1 3.6e-14 53.2 0.1 2.1 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDS30243.1 - 4.1e-08 33.0 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 CDS30243.1 - 2.3e-07 30.8 2.6 1.4e-06 28.3 2.6 2.5 1 0 0 1 1 1 1 FERM adjacent (FA) RhoGEF PF00621.20 CDS30243.1 - 0.00033 20.9 3.7 0.03 14.6 0.0 3.4 4 0 0 4 4 4 2 RhoGEF domain PH_11 PF15413.6 CDS30243.1 - 0.00047 20.5 0.3 0.49 10.9 0.0 3.2 2 0 0 2 2 2 2 Pleckstrin homology domain AAA_23 PF13476.6 CDS30244.1 - 3e-28 99.7 0.0 3e-28 99.7 0.0 8.4 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.6 CDS30244.1 - 4e-14 53.1 5.4 6.5e-08 32.7 0.5 4.6 1 1 2 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 CDS30244.1 - 5.4e-11 42.8 0.3 0.00048 20.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDS30244.1 - 4.1e-08 32.9 29.0 2.5e-06 27.1 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDS30244.1 - 2.2e-05 24.6 0.0 7.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.14 CDS30244.1 - 0.00063 19.5 0.1 0.00063 19.5 0.1 5.1 4 0 0 4 4 4 1 Rad50 zinc hook motif AAA_29 PF13555.6 CDS30244.1 - 0.00094 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Y1_Tnp PF01797.16 CDS30244.1 - 0.037 14.1 0.2 5 7.2 0.0 3.4 2 0 0 2 2 2 0 Transposase IS200 like AAA_16 PF13191.6 CDS30244.1 - 0.037 14.4 0.0 0.037 14.4 0.0 5.8 6 2 0 6 6 5 0 AAA ATPase domain AAA_13 PF13166.6 CDS30244.1 - 0.04 12.6 114.1 0.29 9.7 17.4 7.8 4 2 4 8 8 8 0 AAA domain ABC_tran PF00005.27 CDS30244.1 - 0.069 13.7 0.1 0.069 13.7 0.1 7.5 4 3 0 4 4 1 0 ABC transporter AAA_5 PF07728.14 CDS30244.1 - 0.071 13.1 1.3 0.33 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDS30244.1 - 0.093 13.1 0.5 0.85 9.9 0.1 2.9 2 0 0 2 2 1 0 AAA domain MscS_porin PF12795.7 CDS30244.1 - 1.1 8.8 117.0 0.13 11.7 11.3 8.5 5 3 3 8 8 8 0 Mechanosensitive ion channel porin domain AAA PF00004.29 CDS30244.1 - 1.1 9.7 4.1 2.4 8.6 0.3 3.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.12 CDS30244.1 - 1.2 9.2 47.4 0.32 11.0 1.6 8.2 4 4 6 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 CDS30244.1 - 1.9 8.8 6.1 0.59 10.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Glyco_hydro_47 PF01532.20 CDS30245.2 - 6.2e-131 437.4 0.0 7.1e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2517 PF10725.9 CDS30245.2 - 0.015 15.1 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) AA_permease_C PF13906.6 CDS30245.2 - 0.16 12.1 0.5 0.41 10.8 0.5 1.6 1 0 0 1 1 1 0 C-terminus of AA_permease SH2 PF00017.24 CDS30246.1 - 1.7e-16 60.1 0.0 3.5e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HPD PF05044.12 CDS30248.1 - 1.1e-68 230.0 1.7 1.7e-68 229.4 1.7 1.2 1 0 0 1 1 1 1 Homeo-prospero domain Pkinase PF00069.25 CDS30251.1 - 1.9e-40 138.9 0.0 1.8e-21 76.7 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30251.1 - 1.1e-09 38.0 0.1 0.00095 18.5 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase MCM PF00493.23 CDS30252.1 - 3.9e-71 238.7 0.0 9.7e-65 217.8 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 CDS30252.1 - 2.7e-26 91.8 2.4 7.8e-26 90.3 2.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CDS30252.1 - 6.2e-20 71.3 0.9 6.2e-20 71.3 0.9 3.1 3 0 0 3 3 3 1 MCM OB domain zf-CCCH_2 PF14608.6 CDS30252.1 - 1.4e-11 44.4 56.8 0.00025 21.4 2.8 5.8 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger AAA_5 PF07728.14 CDS30252.1 - 2.8e-07 30.6 0.0 1.6e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDS30252.1 - 2.8e-06 26.9 0.1 0.002 17.6 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI PWI PF01480.17 CDS30252.1 - 9.5e-06 25.8 0.4 2.2e-05 24.7 0.4 1.7 1 0 0 1 1 1 1 PWI domain AAA_16 PF13191.6 CDS30252.1 - 0.0012 19.2 0.3 0.014 15.8 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 CDS30252.1 - 0.071 13.0 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CDS30252.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LIM PF00412.22 CDS30253.1 - 1.4e-05 25.2 12.8 3.7e-05 23.9 9.6 2.3 1 1 1 2 2 2 2 LIM domain HypA PF01155.19 CDS30253.1 - 0.0089 16.0 0.6 0.019 15.0 0.6 1.5 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TPR_12 PF13424.6 CDS30254.1 - 5.1e-12 45.9 5.1 2.8e-07 30.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDS30254.1 - 3.5e-09 36.2 0.0 0.099 12.5 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 CDS30254.1 - 8.8e-06 25.5 7.1 8.8e-06 25.5 7.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS30254.1 - 5.4e-05 23.0 9.3 5.4e-05 23.0 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS30254.1 - 0.0001 22.3 10.5 0.0001 22.3 10.5 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS30254.1 - 0.02 15.1 14.6 0.033 14.4 11.0 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_8 PF13181.6 CDS30254.1 - 0.057 13.7 7.1 32 5.1 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30254.1 - 0.16 11.8 12.4 3.5 7.6 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 CDS30254.1 - 0.16 11.9 16.7 0.027 14.4 11.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain TPR_7 PF13176.6 CDS30254.1 - 0.18 11.9 2.0 11 6.3 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 CDS30254.1 - 0.35 11.2 15.4 0.03 14.7 9.5 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 CDS30254.1 - 0.57 10.1 5.9 1.9 8.4 5.9 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CDS30254.1 - 0.73 9.7 15.7 0.047 13.5 9.2 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS30254.1 - 0.74 10.1 6.6 2.7 8.3 6.6 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDS30254.1 - 1.2 9.1 14.6 0.17 11.8 8.6 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 HSD3 PF15244.6 CDS30255.1 - 4.2e-06 26.5 18.9 5.5e-05 22.9 0.0 3.2 2 1 1 3 3 3 2 Spermatogenesis-associated protein 7, or HSD3 DNApol3-delta_C PF09115.10 CDS30255.1 - 0.036 14.6 0.2 0.069 13.7 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal HTH_25 PF13413.6 CDS30255.1 - 0.048 13.5 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_2 PF07719.17 CDS30256.1 - 7.4e-19 66.3 13.9 0.0001 22.1 0.0 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30256.1 - 9.5e-18 63.4 27.7 0.00058 20.5 0.0 9.6 8 2 2 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30256.1 - 4.9e-15 54.6 11.7 0.0001 22.0 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30256.1 - 7e-15 53.9 15.7 8e-06 25.7 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDS30256.1 - 2.3e-14 52.6 2.3 0.002 18.4 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30256.1 - 2.9e-11 43.8 15.2 4.7e-05 24.0 0.1 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS30256.1 - 1.7e-10 40.4 9.8 0.0074 16.0 0.0 7.6 7 2 3 10 10 10 3 TPR repeat TPR_19 PF14559.6 CDS30256.1 - 1.8e-10 41.2 24.3 1.6e-06 28.5 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS30256.1 - 9.9e-07 28.9 18.6 0.00075 19.7 0.9 6.4 5 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDS30256.1 - 1e-06 28.9 8.6 0.00015 22.0 1.8 6.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDS30256.1 - 0.00018 21.8 12.7 0.021 15.1 0.4 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS30256.1 - 0.00023 21.2 7.7 0.97 9.6 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 CDS30256.1 - 0.013 15.2 4.3 0.095 12.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CDS30256.1 - 0.017 15.0 5.1 6.3 6.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS30256.1 - 0.033 14.8 0.0 0.033 14.8 0.0 5.3 7 0 0 7 7 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS30256.1 - 0.13 12.4 7.7 10 6.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 CDS30256.1 - 0.22 10.5 3.9 9.8 5.1 0.1 3.2 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 CDS30256.1 - 2.1 7.6 11.3 0.11 11.9 0.3 3.6 3 1 0 3 3 3 0 MalT-like TPR region Mito_carr PF00153.27 CDS30257.1 - 1.1e-62 207.9 0.1 5.9e-21 74.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein RLL PF10036.9 CDS30257.1 - 5.9e-40 137.7 0.1 8.2e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein DUF5518 PF17647.1 CDS30257.1 - 0.045 13.9 2.6 0.83 9.8 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Integrase_DNA PF02920.15 CDS30259.2 - 0.17 11.6 0.0 0.54 10.0 0.0 1.7 1 1 1 2 2 2 0 DNA binding domain of tn916 integrase RNase_PH PF01138.21 CDS30260.2 - 7.6e-24 84.7 0.0 1.2e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDS30260.2 - 4.6e-08 33.0 0.3 1e-07 31.9 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 UQ_con PF00179.26 CDS30261.2 - 9.8e-40 135.4 0.0 1.3e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 CDS30261.2 - 3e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 CDS30261.2 - 2e-07 30.8 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_4 PF14555.6 CDS30261.2 - 0.0067 16.2 1.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain RWD PF05773.22 CDS30261.2 - 0.044 14.1 0.1 0.074 13.3 0.0 1.6 1 1 0 1 1 1 0 RWD domain cNMP_binding PF00027.29 CDS30262.1 - 9e-39 131.5 0.4 1.6e-19 69.8 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CDS30262.1 - 6.7e-12 44.9 0.0 1.5e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 CDS30262.1 - 0.092 12.5 1.7 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Cupin domain Inj_translocase PF16928.5 CDS30262.1 - 0.094 12.2 0.2 0.24 10.8 0.2 1.6 1 1 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome TraC_F_IV PF11130.8 CDS30262.1 - 0.14 11.8 0.1 6.6 6.3 0.0 2.2 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer tRNA-synt_2 PF00152.20 CDS30263.1 - 2.6e-76 256.7 0.0 3.3e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDS30263.1 - 2.5e-11 43.4 0.1 5.2e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDS30263.1 - 0.00026 20.6 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FxsA PF04186.13 CDS30264.1 - 0.04 14.0 0.3 0.048 13.8 0.3 1.1 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF3316 PF11777.8 CDS30264.1 - 0.1 12.7 1.5 0.11 12.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) DUF4064 PF13273.6 CDS30266.1 - 0.049 13.9 0.8 0.059 13.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2448 PF10476.9 CDS30266.1 - 0.11 12.3 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Peptidase_M16_M PF16187.5 CDS30270.2 - 6.4e-78 261.9 0.3 1.9e-77 260.3 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDS30270.2 - 1e-35 122.9 0.1 5.9e-35 120.4 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDS30270.2 - 3.2e-35 121.8 0.4 1.9e-18 67.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF1104 PF06518.11 CDS30270.2 - 0.046 14.1 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) EthD PF07110.11 CDS30270.2 - 0.11 13.7 2.2 2.7 9.2 0.0 3.1 3 0 0 3 3 3 0 EthD domain FerA PF08165.11 CDS30271.1 - 0.027 14.4 0.1 2.9 7.9 0.0 2.9 2 0 0 2 2 2 0 FerA (NUC095) domain DUF1400 PF07176.11 CDS30271.1 - 0.048 13.9 0.5 0.18 12.1 0.2 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Polo_box_3 PF18544.1 CDS30271.1 - 0.09 13.4 0.1 0.33 11.6 0.0 1.9 2 0 0 2 2 2 0 Polo box domain IZUMO PF15005.6 CDS30271.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated ATP-synt_F PF01990.17 CDS30272.1 - 7.3e-32 109.6 0.1 8.3e-32 109.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit BTB PF00651.31 CDS30273.2 - 3.9e-21 75.3 0.2 7.4e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain BCAS3 PF12490.8 CDS30273.2 - 2.9e-06 27.0 6.4 0.011 15.3 0.0 3.1 4 0 0 4 4 4 2 Breast carcinoma amplified sequence 3 DUF3342 PF11822.8 CDS30273.2 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB_2 PF02214.22 CDS30273.2 - 0.0013 19.1 0.2 0.006 16.9 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain RIC3 PF15361.6 CDS30273.2 - 0.48 10.8 2.7 2.3 8.6 1.0 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 WD40 PF00400.32 CDS30273.2 - 1.4 9.9 3.6 17 6.5 0.2 3.5 2 0 0 2 2 2 0 WD domain, G-beta repeat ORC6 PF05460.13 CDS30273.2 - 9.5 5.4 14.5 19 4.4 14.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CytochromB561_N PF09786.9 CDS30276.2 - 3.2e-46 158.5 9.4 1.5e-45 156.3 9.4 1.9 1 1 0 1 1 1 1 Cytochrome B561, N terminal CAP PF00188.26 CDS30277.2 - 6.3e-09 36.7 0.2 1.3e-08 35.8 0.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family JAMP PF05571.12 CDS30277.2 - 0.081 12.5 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein ADD_DNMT3 PF17980.1 CDS30277.2 - 0.15 12.1 2.5 0.29 11.1 2.5 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 rve PF00665.26 CDS30278.1 - 1.9e-09 37.8 0.0 2.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Bromodomain PF00439.25 CDS30279.2 - 4.8e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CDS30279.2 - 7.1e-05 22.6 12.6 0.0002 21.2 9.0 2.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 CDS30279.2 - 0.16 12.2 4.3 0.56 10.4 4.3 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDS30279.2 - 0.37 11.1 5.0 1.1 9.5 5.0 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 CDS30279.2 - 0.85 9.8 12.7 0.31 11.2 9.1 2.2 2 1 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 CDS30279.2 - 1.6 8.7 15.5 0.025 14.4 3.9 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sec2p PF06428.11 CDS30280.2 - 1.3e-05 25.0 7.4 3.2e-05 23.8 7.4 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p bZIP_2 PF07716.15 CDS30280.2 - 0.0049 16.9 5.8 0.98 9.6 0.6 2.5 2 0 0 2 2 2 2 Basic region leucine zipper HALZ PF02183.18 CDS30280.2 - 0.027 14.7 5.6 0.14 12.4 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tubulin_3 PF14881.6 CDS30280.2 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain bZIP_1 PF00170.21 CDS30280.2 - 0.2 11.8 9.8 0.61 10.2 1.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor Fungal_TACC PF12709.7 CDS30280.2 - 0.22 12.0 8.9 0.21 12.1 1.8 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Speriolin_N PF15058.6 CDS30280.2 - 0.29 11.2 6.7 0.15 12.1 0.8 2.4 1 1 1 2 2 2 0 Speriolin N terminus Ax_dynein_light PF10211.9 CDS30280.2 - 0.32 10.9 7.3 0.55 10.2 7.3 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain PRKG1_interact PF15898.5 CDS30280.2 - 0.48 11.3 5.9 1.2 10.1 5.9 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain FapA PF03961.13 CDS30280.2 - 0.54 8.8 4.0 0.77 8.3 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 CDS30280.2 - 0.69 10.1 5.6 0.7 10.1 0.8 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4472 PF14739.6 CDS30280.2 - 0.84 10.4 8.3 1.6 9.5 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) DASH_Spc19 PF08287.11 CDS30280.2 - 1 9.2 6.0 3.3 7.6 5.5 2.0 1 1 1 2 2 2 0 Spc19 Cnn_1N PF07989.11 CDS30280.2 - 2.8 8.2 7.7 6.2 7.1 1.1 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Sec1 PF00995.23 CDS30281.1 - 7.4e-105 352.4 0.0 1.2e-104 351.7 0.0 1.3 1 1 0 1 1 1 1 Sec1 family GDI PF00996.18 CDS30282.1 - 1.3e-210 699.4 0.3 1.5e-210 699.2 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CDS30282.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase TMF_DNA_bd PF12329.8 CDS30285.1 - 7.8e-09 35.4 13.7 7.8e-09 35.4 13.7 6.9 3 1 5 8 8 8 2 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.8 CDS30285.1 - 0.002 17.8 4.0 0.002 17.8 4.0 5.4 1 1 5 6 6 6 2 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.9 CDS30285.1 - 0.014 15.5 21.3 0.014 15.5 21.3 5.9 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 CDS30285.1 - 0.27 10.6 70.9 0.29 10.5 37.9 3.3 2 1 1 3 3 3 0 Tropomyosin DUF1664 PF07889.12 CDS30285.1 - 0.59 10.2 38.4 0.34 10.9 5.0 5.2 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDS30285.1 - 2.1 8.9 80.0 0.027 15.0 10.3 5.8 2 1 4 6 6 6 0 Apg6 coiled-coil region GAS PF13851.6 CDS30285.1 - 3.1 7.1 70.8 1.2 8.4 11.2 6.0 3 1 2 6 6 6 0 Growth-arrest specific micro-tubule binding Paf1 PF03985.13 CDS30286.1 - 4.2e-136 454.3 13.3 4.2e-136 454.3 13.3 1.8 1 1 0 2 2 2 1 Paf1 DUF3236 PF11576.8 CDS30287.1 - 0.0089 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3236) Pkinase_Tyr PF07714.17 CDS30288.1 - 1.8e-79 266.7 0.0 2.4e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS30288.1 - 3.1e-39 135.0 0.0 4.6e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_2 PF07653.17 CDS30288.1 - 2e-05 24.2 0.0 5.4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 CDS30288.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 CDS30288.1 - 0.027 14.8 0.1 0.068 13.5 0.1 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain SAM_1 PF00536.30 CDS30288.1 - 0.049 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 CDS30288.1 - 0.049 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain SH3_1 PF00018.28 CDS30288.1 - 0.052 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Kdo PF06293.14 CDS30288.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tnp_DNA_bind PF14706.6 CDS30289.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Transposase DNA-binding Ion_trans PF00520.31 CDS30290.2 - 3.1e-32 111.8 14.5 4.2e-32 111.3 14.5 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CDS30290.2 - 1.4e-13 50.7 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDS30290.2 - 2.9e-09 36.7 3.1 2.9e-09 36.7 3.1 2.1 2 0 0 2 2 2 1 Ion channel PAS_9 PF13426.7 CDS30290.2 - 5.7e-08 33.0 0.0 1.6e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain Cupin_2 PF07883.11 CDS30290.2 - 0.017 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF261 PF03196.13 CDS30290.2 - 0.35 11.0 1.7 0.54 10.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF261 NifU_N PF01592.16 CDS30292.1 - 2.2e-48 163.6 0.1 2.6e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain FAIM1 PF06905.13 CDS30293.1 - 5.5e-07 29.5 0.0 6.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) SNF PF00209.18 CDS30294.2 - 1.1e-132 443.5 27.9 1.5e-114 383.6 14.2 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family RPEL PF02755.15 CDS30295.1 - 1.2e-09 37.5 5.4 0.00033 20.2 2.4 2.6 2 0 0 2 2 2 2 RPEL repeat Herpes_UL6 PF01763.16 CDS30296.1 - 0.092 11.3 0.4 0.1 11.1 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Phostensin_N PF13916.6 CDS30296.1 - 0.15 12.5 0.9 0.15 12.5 0.9 3.1 1 1 2 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal VHP PF02209.19 CDS30296.1 - 2.8 8.1 5.3 3.2 7.9 0.5 2.8 3 0 0 3 3 3 0 Villin headpiece domain Ephrin_rec_like PF07699.13 CDS30297.1 - 7.1e-09 35.3 5.9 2.1e-07 30.6 2.5 2.6 2 0 0 2 2 2 2 Putative ephrin-receptor like DUF4709 PF15821.5 CDS30297.1 - 0.16 12.3 0.1 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) CN_hydrolase PF00795.22 CDS30298.1 - 5.6e-54 183.2 0.0 6.6e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MutS_V PF00488.21 CDS30299.1 - 4.1e-22 79.1 0.0 6.9e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDS30299.1 - 6.4e-11 42.8 0.0 9.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CDS30299.1 - 1.3e-07 31.9 0.0 1.4e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 CDS30299.1 - 0.00087 19.3 0.0 0.0043 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CDS30299.1 - 0.01 16.3 0.1 0.027 15.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDS30299.1 - 0.05 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 CDS30299.1 - 0.062 13.2 0.1 0.92 9.4 0.1 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDS30299.1 - 0.092 13.0 0.1 0.85 9.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDS30299.1 - 0.11 12.8 0.0 1.6 9.1 0.0 2.8 2 2 1 3 3 3 0 AAA ATPase domain Pkinase PF00069.25 CDS30300.1 - 3.5e-51 174.1 0.0 4.8e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30300.1 - 4e-22 78.7 0.0 8.4e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CDS30300.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDS30300.1 - 0.053 13.4 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family LMBR1 PF04791.16 CDS30301.1 - 5.3e-90 302.8 1.2 8.4e-90 302.1 1.2 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Wzy_C PF04932.15 CDS30301.1 - 6.7 6.3 6.9 18 4.9 1.0 3.0 3 0 0 3 3 3 0 O-Antigen ligase UAA PF08449.11 CDS30302.1 - 3.8e-65 220.1 30.9 4.4e-65 219.8 30.9 1.0 1 0 0 1 1 1 1 UAA transporter family Phage_holin_2_4 PF16082.5 CDS30302.1 - 0.16 11.7 0.3 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like EamA PF00892.20 CDS30302.1 - 0.19 11.9 40.4 0.38 10.9 19.6 2.8 2 1 1 3 3 3 0 EamA-like transporter family MMR_HSR1 PF01926.23 CDS30303.1 - 7.7e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS30303.1 - 5.8e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS30303.1 - 6.6e-07 29.5 0.5 0.037 14.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Arf PF00025.21 CDS30303.1 - 0.00079 18.9 0.1 0.0091 15.5 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.16 CDS30303.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CDS30303.1 - 0.0043 17.0 0.1 0.24 11.3 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 CDS30303.1 - 0.0097 15.7 0.0 1.8 8.3 0.0 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation KH_1 PF00013.29 CDS30303.1 - 0.017 14.9 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 KH domain Roc PF08477.13 CDS30303.1 - 0.035 14.3 0.0 0.098 12.9 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Radical_SAM_C PF16199.5 CDS30304.1 - 3e-31 107.3 0.0 9.5e-31 105.7 0.0 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CDS30304.1 - 3.5e-19 69.8 1.0 1.2e-18 68.0 0.2 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CDS30304.1 - 1.9e-09 37.8 0.0 5.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDS30304.1 - 5.4e-06 26.4 0.0 1.6e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDS30304.1 - 0.0068 16.8 0.1 0.015 15.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PP2C_C PF07830.13 CDS30304.1 - 0.055 13.9 0.2 0.12 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain FR47 PF08445.10 CDS30304.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein LSM PF01423.22 CDS30305.1 - 3.4e-18 65.1 0.2 3.9e-18 64.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDS30305.1 - 0.03 14.5 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CDS30305.1 - 0.053 13.6 0.1 0.078 13.1 0.1 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Orthoreo_P10 PF07204.11 CDS30306.1 - 0.0031 17.4 5.4 0.27 11.2 0.0 2.3 1 1 1 2 2 2 2 Orthoreovirus membrane fusion protein p10 FAM176 PF14851.6 CDS30306.1 - 0.019 14.6 0.7 4.2 7.0 0.3 2.2 2 0 0 2 2 2 0 FAM176 family GSHPx PF00255.19 CDS30308.2 - 6.1e-27 93.3 1.1 1.1e-24 86.1 0.3 2.1 1 1 1 2 2 2 2 Glutathione peroxidase Npa1 PF11707.8 CDS30309.1 - 8.9e-42 143.6 1.0 1.8e-41 142.7 0.4 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CDS30309.1 - 2.1e-41 141.7 0.2 9.5e-41 139.6 0.2 2.2 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 FPL PF09758.9 CDS30310.2 - 1.1e-36 126.1 12.7 1.9e-32 112.3 3.2 3.1 2 1 1 3 3 3 2 Uncharacterised conserved protein DUF3361 PF11841.8 CDS30310.2 - 0.073 13.0 1.3 0.17 11.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) fn3 PF00041.21 CDS30311.2 - 2.4e-12 47.0 0.1 1.2e-07 32.0 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Endothelin PF00322.17 CDS30312.2 - 0.25 11.0 2.8 2.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Endothelin family PDZ PF00595.24 CDS30313.2 - 4.5e-35 119.9 1.1 8.8e-18 64.4 0.2 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDS30313.2 - 1.3e-18 66.5 1.1 2.6e-09 36.8 0.2 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDS30313.2 - 8e-09 35.7 0.1 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain L27_1 PF09058.10 CDS30313.2 - 4.3e-06 26.6 0.1 9.6e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 L27_1 IF3_N PF05198.16 CDS30313.2 - 0.0071 16.6 0.1 6.1 7.2 0.0 2.3 2 0 0 2 2 2 2 Translation initiation factor IF-3, N-terminal domain Tricorn_PDZ PF14685.6 CDS30313.2 - 0.12 12.4 0.1 0.84 9.6 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain HMG_box PF00505.19 CDS30314.2 - 2.3e-21 76.0 1.9 2.3e-21 76.0 1.9 2.2 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS30314.2 - 1.9e-08 34.8 0.7 1.9e-08 34.8 0.7 2.5 3 0 0 3 3 3 1 HMG-box domain LptF_LptG PF03739.14 CDS30314.2 - 0.47 9.2 2.0 0.3 9.9 0.2 1.5 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG EF-hand_2 PF09068.11 CDS30315.2 - 1.6e-27 96.1 0.0 8.5e-27 93.7 0.0 2.5 1 0 0 1 1 1 1 EF hand EF-hand_3 PF09069.11 CDS30315.2 - 1.8e-17 63.5 0.0 1.7e-16 60.4 0.0 2.9 2 0 0 2 2 1 1 EF-hand ZZ PF00569.17 CDS30315.2 - 1e-10 41.2 6.3 2.7e-10 39.9 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type WW PF00397.26 CDS30315.2 - 4.9e-05 23.3 1.2 0.00013 22.0 1.2 1.7 1 0 0 1 1 1 1 WW domain Nucleolin_bd PF16725.5 CDS30315.2 - 0.0064 16.1 1.2 0.058 13.1 0.1 3.3 3 0 0 3 3 3 1 Nucleolin binding domain C1_2 PF03107.16 CDS30315.2 - 0.059 13.7 5.7 0.13 12.6 5.7 1.6 1 0 0 1 1 1 0 C1 domain Mce4_CUP1 PF11887.8 CDS30315.2 - 0.073 12.5 6.5 0.078 12.4 0.0 4.0 4 0 0 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative COMM_domain PF07258.14 CDS30315.2 - 0.13 12.4 6.4 4.7 7.4 0.1 5.2 5 0 0 5 5 5 0 COMM domain mCpol PF18182.1 CDS30315.2 - 0.19 12.1 3.7 7.2 7.0 0.1 4.8 5 0 0 5 5 4 0 minimal CRISPR polymerase domain COMP PF11598.8 CDS30315.2 - 1.2 9.6 3.9 8.5 6.9 0.2 4.7 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein zf-B_box PF00643.24 CDS30315.2 - 1.6 8.9 6.1 3.9 7.7 6.1 1.6 1 0 0 1 1 1 0 B-box zinc finger RasGEF PF00617.19 CDS30315.2 - 5.6 7.1 8.6 20 5.3 0.1 5.1 4 0 0 4 4 4 0 RasGEF domain Pkinase PF00069.25 CDS30316.1 - 6.6e-62 209.3 0.0 2.3e-61 207.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30316.1 - 3.1e-31 108.6 0.1 7.7e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS30316.1 - 1.3e-09 37.8 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS30316.1 - 0.0039 16.6 1.4 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_1 PF00130.22 CDS30316.1 - 0.0047 16.8 8.7 0.0094 15.8 8.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 CDS30316.1 - 0.013 15.4 0.3 0.013 15.4 0.3 3.6 3 2 1 4 4 4 0 Phosphotransferase enzyme family PH PF00169.29 CDS30316.1 - 0.051 14.1 0.3 0.73 10.4 0.0 2.4 2 0 0 2 2 2 0 PH domain Seadorna_VP7 PF07387.11 CDS30316.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Exonuc_VII_L PF02601.15 CDS30316.1 - 0.6 9.6 34.6 3 7.3 14.2 3.4 3 0 0 3 3 3 0 Exonuclease VII, large subunit JAB PF01398.21 CDS30317.1 - 2e-09 37.5 0.3 1.9e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDS30317.1 - 4.8e-09 36.6 0.1 7.8e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function MATH PF00917.26 CDS30319.1 - 3.2e-06 27.3 2.3 1.4e-05 25.2 0.3 2.8 2 1 0 3 3 3 1 MATH domain Pallilysin PF18663.1 CDS30319.1 - 0.077 13.0 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Pallilysin beta barrel domain FXa_inhibition PF14670.6 CDS30320.1 - 1.4e-45 153.2 129.2 3.8e-10 39.9 11.9 35.2 15 5 13 28 28 28 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CDS30320.1 - 9.1e-26 89.4 52.1 1.3e-09 37.8 0.9 36.9 36 7 2 38 38 38 9 Complement Clr-like EGF-like Laminin_EGF PF00053.24 CDS30320.1 - 1.6e-21 76.2 542.7 0.00059 19.9 13.6 31.7 12 8 20 32 32 32 18 Laminin EGF domain EGF_CA PF07645.15 CDS30320.1 - 1.1e-18 67.1 55.6 9.7e-10 38.5 6.5 31.9 18 8 12 30 30 30 5 Calcium-binding EGF domain EGF PF00008.27 CDS30320.1 - 2.9e-05 24.3 36.8 0.00049 20.3 8.1 39.9 36 5 3 39 39 39 15 EGF-like domain hEGF PF12661.7 CDS30320.1 - 0.00027 21.4 18.5 0.00042 20.8 5.6 40.3 41 6 3 44 44 44 19 Human growth factor-like EGF DSL PF01414.19 CDS30320.1 - 0.00036 20.8 30.3 0.0005 20.3 9.9 28.8 24 6 8 32 32 32 8 Delta serrate ligand EGF_2 PF07974.13 CDS30320.1 - 0.0028 18.0 11.5 0.0028 18.0 11.5 45.2 34 16 9 43 43 43 13 EGF-like domain eIF3g PF12353.8 CDS30321.2 - 8.4e-33 113.4 1.0 1.3e-32 112.8 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CDS30321.2 - 1.5e-19 69.6 0.0 2.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YscJ_FliF_C PF08345.11 CDS30321.2 - 0.0081 16.5 1.4 0.74 10.1 0.2 2.5 3 0 0 3 3 3 1 Flagellar M-ring protein C-terminal Nup35_RRM_2 PF14605.6 CDS30321.2 - 0.01 15.8 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDS30321.2 - 0.031 14.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CDS30321.2 - 0.037 14.3 1.8 5.9 7.1 0.2 2.6 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Hen1_L PF12623.7 CDS30321.2 - 0.05 12.6 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 RRM_1 PF00076.22 CDS30322.1 - 2.2e-14 53.0 0.3 1.1e-06 28.3 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FancD2 PF14631.6 CDS30323.1 - 8.7e-55 185.8 19.6 1.8e-35 121.8 0.1 3.2 3 0 0 3 3 3 3 Fanconi anaemia protein FancD2 nuclease Ras PF00071.22 CDS30324.1 - 2.7e-21 75.9 0.0 8.4e-21 74.2 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDS30324.1 - 1.3e-12 48.0 0.0 1e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30324.1 - 5.3e-05 22.7 0.0 0.0009 18.7 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS30324.1 - 0.006 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDS30324.1 - 0.0066 15.9 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit T2SS_PulS_OutS PF09691.10 CDS30324.1 - 0.012 15.8 0.0 4.2 7.6 0.0 2.4 1 1 1 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) ArAE_2_N PF10337.9 CDS30330.1 - 6 5.8 14.4 8.2 5.3 14.4 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal HTH_11 PF08279.12 CDS30333.1 - 0.09 12.7 0.1 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 HTH domain DUF2070 PF09843.9 CDS30334.1 - 0.56 8.4 7.6 0.64 8.2 7.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2371 PF10177.9 CDS30334.1 - 1.4 9.1 4.2 27 4.9 4.2 2.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF973 PF06157.11 CDS30334.1 - 3.3 6.7 10.3 8.3 5.4 10.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF2070 PF09843.9 CDS30335.1 - 2 6.6 8.1 2.1 6.6 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 CDS30335.1 - 3.6 7.2 5.1 1 9.0 0.9 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) DLIC PF05783.11 CDS30336.1 - 2.5e-121 405.8 0.2 2.3e-69 234.5 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 CDS30336.1 - 2e-06 27.5 0.3 0.037 13.5 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Roc PF08477.13 CDS30336.1 - 1.3e-05 25.4 0.1 4.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDS30336.1 - 0.0027 17.6 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 CDS30336.1 - 0.0027 17.2 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family DD_K PF12121.8 CDS30336.1 - 0.0063 16.6 0.6 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 Dermaseptin ABC_tran PF00005.27 CDS30336.1 - 0.022 15.3 0.0 0.051 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CDS30336.1 - 0.023 14.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CDS30336.1 - 0.042 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Ras PF00071.22 CDS30336.1 - 0.047 13.3 0.0 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 CDS30336.1 - 0.049 13.7 0.1 0.35 11.0 0.0 2.3 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDS30336.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynein_light PF01221.18 CDS30337.1 - 2.6e-28 98.2 0.3 2.8e-28 98.0 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 CDS30337.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Dynein_light PF01221.18 CDS30338.1 - 8.7e-25 86.9 0.1 9.8e-25 86.7 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CDS30338.1 - 0.068 13.8 0.0 0.094 13.4 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain Dynein_light PF01221.18 CDS30339.1 - 9.1e-27 93.2 0.2 1e-26 93.1 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CDS30339.1 - 0.029 15.0 0.1 0.035 14.8 0.1 1.3 1 0 0 1 1 1 0 Ground-like domain Topo_C_assoc PF14370.6 CDS30339.1 - 0.08 12.9 0.2 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 C-terminal topoisomerase domain Glyco_transf_15 PF01793.16 CDS30339.1 - 0.083 12.1 0.0 0.087 12.1 0.0 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase HTH_11 PF08279.12 CDS30341.1 - 0.01 15.7 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 CDS30341.1 - 0.044 13.4 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF5063 PF16702.5 CDS30341.1 - 0.085 13.2 0.1 0.098 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) DUF2070 PF09843.9 CDS30342.2 - 0.79 7.9 8.7 0.92 7.7 8.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 7TM_GPCR_Srw PF10324.9 CDS30343.1 - 2.5e-25 89.4 13.2 8e-18 64.8 6.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS30343.1 - 4e-10 39.5 7.5 5.3e-10 39.1 7.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RRM_1 PF00076.22 CDS30348.1 - 4.6e-26 90.4 0.8 7.9e-14 51.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS30348.1 - 5.1e-08 32.9 0.2 0.0009 19.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CDS30348.1 - 0.0016 18.1 0.0 1.2 8.7 0.0 2.4 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDS30348.1 - 0.014 15.4 0.3 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS30348.1 - 0.096 12.7 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Claudin_2 PF13903.6 CDS30349.1 - 2.2e-05 24.3 14.7 0.00029 20.7 8.0 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 CDS30349.1 - 0.00077 19.7 14.3 0.002 18.3 14.4 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein TMEM51 PF15345.6 CDS30349.1 - 0.02 14.7 0.3 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Renin_r PF07850.14 CDS30349.1 - 0.071 13.7 4.0 2.1 9.0 0.1 3.2 3 0 0 3 3 3 0 Renin receptor-like protein SUa-2TM PF18179.1 CDS30349.1 - 0.34 10.2 2.6 0.66 9.2 2.6 1.5 1 1 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain TatC PF00902.18 CDS30349.1 - 0.77 9.5 10.5 1.3 8.8 10.5 1.4 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF2157 PF09925.9 CDS30349.1 - 2.9 7.7 13.6 33 4.2 0.0 3.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) CD20 PF04103.15 CDS30349.1 - 6.6 6.8 19.9 0.39 10.8 3.5 3.1 2 1 1 3 3 3 0 CD20-like family DUF872 PF05915.12 CDS30349.1 - 7.1 6.8 7.2 2.7 8.2 1.2 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CAP_N PF01213.19 CDS30350.1 - 2 7.8 6.8 0.46 9.9 2.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TIM21 PF08294.11 CDS30351.1 - 1.6e-36 125.4 0.0 2.5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CDS30351.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CDI PF02234.19 CDS30352.1 - 0.00016 21.8 0.4 0.00032 20.8 0.4 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Tubulin PF00091.25 CDS30353.1 - 3.4e-69 233.0 0.0 5.4e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS30353.1 - 1.9e-43 147.6 0.1 3.1e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS30353.1 - 1.4e-05 25.3 0.0 3.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS30353.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS30353.1 - 0.041 13.1 0.1 0.085 12.0 0.0 1.5 2 0 0 2 2 2 0 Tubulin like LRR_8 PF13855.6 CDS30355.1 - 5.6 6.8 7.8 11 5.9 0.1 4.2 4 1 0 4 4 4 0 Leucine rich repeat zf-CHY PF05495.12 CDS30356.1 - 0.023 15.2 0.7 0.1 13.1 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger MAP65_ASE1 PF03999.12 CDS30358.1 - 2.1e-28 99.4 19.6 2.6e-28 99.1 19.6 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Takusan PF04822.13 CDS30358.1 - 0.015 15.1 3.3 0.18 11.7 1.1 2.9 2 0 0 2 2 2 0 Takusan DivIC PF04977.15 CDS30358.1 - 0.035 13.9 0.8 0.71 9.7 0.0 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF3450 PF11932.8 CDS30358.1 - 0.038 13.3 0.8 0.87 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 CDS30358.1 - 0.13 12.3 3.8 0.2 11.8 1.1 2.8 2 1 0 2 2 2 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 CDS30358.1 - 0.29 11.3 5.9 1.6 8.9 0.2 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain HAUS-augmin3 PF14932.6 CDS30358.1 - 0.42 10.2 6.6 2.2 7.8 0.2 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DivIVA PF05103.13 CDS30358.1 - 0.69 10.0 4.7 6.4 6.9 0.3 2.9 3 0 0 3 3 2 0 DivIVA protein APG6_N PF17675.1 CDS30358.1 - 0.79 10.2 11.2 0.11 13.1 0.8 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CDS30358.1 - 0.8 9.7 8.9 2.1 8.4 0.5 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KNOX2 PF03791.13 CDS30358.1 - 1.2 8.7 6.3 0.089 12.3 0.9 1.9 2 0 0 2 2 2 0 KNOX2 domain Cor1 PF04803.12 CDS30358.1 - 2.2 8.5 6.5 5.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region JIP_LZII PF16471.5 CDS30358.1 - 3.4 7.9 6.0 5.2 7.3 0.2 3.2 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II Jnk-SapK_ap_N PF09744.9 CDS30358.1 - 9.2 6.5 9.7 13 5.9 0.8 3.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 PCI PF01399.27 CDS30359.2 - 2e-08 34.7 0.2 2e-08 34.7 0.2 3.7 4 0 0 4 4 4 1 PCI domain ASC PF00858.24 CDS30360.1 - 1.8e-60 205.2 2.2 2.2e-60 204.9 2.2 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF5619 PF18505.1 CDS30361.2 - 0.16 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) Kunitz_BPTI PF00014.23 CDS30363.1 - 1.6e-06 28.2 4.2 2.2e-06 27.8 4.2 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TFIIA PF03153.13 CDS30368.1 - 6e-54 184.6 31.6 2.6e-33 116.6 0.8 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit CSRNP_N PF16019.5 CDS30368.1 - 2.6 7.9 15.2 3.9 7.3 9.9 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Macoilin PF09726.9 CDS30368.1 - 7.1 5.1 8.9 0.29 9.6 2.9 1.6 2 0 0 2 2 2 0 Macoilin family Branch PF02485.21 CDS30372.1 - 2.3e-27 96.1 0.0 3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RRM_1 PF00076.22 CDS30374.1 - 2.8e-19 68.7 0.1 5.2e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CDS30374.1 - 5.8e-05 23.0 2.0 0.0001 22.2 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDS30374.1 - 0.00032 20.6 0.2 0.00055 19.9 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 CDS30374.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS30374.1 - 0.0024 17.7 0.1 0.004 17.0 0.1 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif BRAP2 PF07576.12 CDS30374.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 BRCA1-associated protein 2 SET_assoc PF11767.8 CDS30374.1 - 0.084 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DNA_topoisoIV PF00521.20 CDS30374.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RRM_8 PF11835.8 CDS30374.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain HTH_psq PF05225.16 CDS30375.1 - 2.9e-12 46.1 0.0 2.4e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain IQ PF00612.27 CDS30376.1 - 0.00065 19.3 3.3 0.0017 18.0 3.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SDF PF00375.18 CDS30377.1 - 1.2e-78 264.8 34.8 1.7e-78 264.4 34.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MFS_2 PF13347.6 CDS30378.2 - 2.8e-07 29.5 13.5 6.5e-06 25.0 13.5 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein DUF4233 PF14017.6 CDS30378.2 - 0.28 11.5 0.1 0.28 11.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) Roc PF08477.13 CDS30381.1 - 0.0057 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS30381.1 - 0.033 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.6 CDS30381.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Y_phosphatase PF00102.27 CDS30382.1 - 5.5e-104 346.9 8.9 7.4e-66 222.1 1.6 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase DSPc PF00782.20 CDS30382.1 - 4e-05 23.4 0.0 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS30382.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDS30382.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate bZIP_Maf PF03131.17 CDS30383.1 - 2.9e-15 56.6 10.6 4.4e-15 56.0 10.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CDS30383.1 - 0.00052 20.1 10.3 0.00092 19.3 10.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cut12 PF11500.8 CDS30383.1 - 0.0018 18.3 2.9 0.0029 17.6 2.9 1.3 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Cytochrom_B561 PF03188.16 CDS30384.1 - 9.3e-08 32.3 5.8 9.3e-08 32.3 5.8 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 CDS30384.1 - 0.00031 20.9 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Claudin_3 PF06653.11 CDS30384.1 - 0.049 13.6 0.7 0.049 13.6 0.7 3.1 3 0 0 3 3 3 0 Tight junction protein, Claudin-like rve PF00665.26 CDS30385.1 - 2.7e-08 34.0 0.0 3.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DUF1754 PF08555.10 CDS30386.1 - 0.012 16.4 4.7 0.033 15.0 4.7 1.8 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PPIP5K2_N PF18086.1 CDS30386.1 - 0.07 13.3 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain DUF4200 PF13863.6 CDS30387.1 - 1.4e-12 48.1 27.4 1.3e-11 45.0 15.7 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) DUF4413 PF14372.6 CDS30387.1 - 0.0096 16.3 1.1 0.065 13.6 0.2 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4413) Vac_Fusion PF02346.16 CDS30387.1 - 0.029 14.0 2.8 1.4 8.6 0.2 3.7 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 60KD_IMP PF02096.20 CDS30387.1 - 0.17 11.8 0.1 0.48 10.3 0.1 1.8 1 0 0 1 1 1 0 60Kd inner membrane protein FUSC PF04632.12 CDS30387.1 - 0.44 9.0 1.0 1.1 7.7 0.0 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 CDS30387.1 - 1.4 9.7 20.8 0.094 13.5 1.9 3.6 2 2 2 4 4 4 0 Occludin homology domain CorA PF01544.18 CDS30387.1 - 1.5 8.1 9.3 1.5 8.1 1.1 2.7 1 1 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 CDS30387.1 - 1.6 9.1 3.7 0.76 10.1 0.2 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CDS30387.1 - 7.4 6.6 14.0 0.51 10.4 1.6 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) LRR_4 PF12799.7 CDS30388.1 - 6.4e-12 45.5 8.0 7.4e-06 26.2 0.9 2.9 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS30388.1 - 4.5e-10 39.1 7.5 0.0004 20.1 0.7 3.7 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CDS30388.1 - 2.4e-07 30.5 1.5 6.4e-06 25.8 0.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDS30388.1 - 0.0006 19.7 1.5 0.8 9.9 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 CDS30388.1 - 0.048 14.2 8.1 5 8.1 0.4 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat DUF3531 PF12049.8 CDS30389.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) LPD22 PF18834.1 CDS30390.1 - 0.035 14.3 0.1 0.1 12.8 0.0 1.7 1 1 1 2 2 2 0 Large polyvalent protein associated domain 22 DUF1943 PF09172.11 CDS30390.1 - 0.34 10.1 2.0 0.41 9.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MCU PF04678.13 CDS30390.1 - 0.53 10.4 2.5 0.81 9.8 2.5 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter MRPL52 PF18699.1 CDS30390.1 - 1 9.6 5.1 2.1 8.6 5.1 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 HTH_AraC PF00165.23 CDS30391.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Innexin PF00876.18 CDS30392.1 - 1.9e-105 353.0 2.9 2.2e-105 352.8 2.9 1.0 1 0 0 1 1 1 1 Innexin Innexin PF00876.18 CDS30393.1 - 1.7e-107 359.8 15.5 2.3e-107 359.3 15.5 1.2 1 0 0 1 1 1 1 Innexin UBX PF00789.20 CDS30394.1 - 4.8e-06 26.7 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CDS30394.1 - 7.9e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CDS30394.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Requiem_N PF14051.6 CDS30396.1 - 3.9e-07 30.2 0.2 1.5e-06 28.3 0.2 2.1 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.29 CDS30396.1 - 2.4e-06 27.3 10.0 2.4e-06 27.3 10.0 3.5 2 1 1 3 3 3 1 PHD-finger MFS_1 PF07690.16 CDS30397.1 - 2.6e-14 52.9 38.2 1.4e-06 27.5 2.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Anoctamin PF04547.12 CDS30397.1 - 0.06 12.2 3.7 0.072 11.9 1.7 2.1 1 1 1 2 2 2 0 Calcium-activated chloride channel Phage_holin_2_3 PF16080.5 CDS30397.1 - 3.4 7.5 6.4 20 5.1 0.3 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 zf-H2C2_2 PF13465.6 CDS30398.1 - 1e-11 44.7 58.2 7.6e-05 23.0 6.4 9.2 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30398.1 - 3.8e-11 42.8 65.2 0.0028 18.0 0.9 8.5 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDS30398.1 - 9.6e-08 31.6 55.6 0.00062 19.5 3.4 6.8 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDS30398.1 - 9.8e-08 32.2 63.8 0.095 13.6 0.8 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS30398.1 - 0.035 14.4 38.7 0.55 10.6 0.3 5.8 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF1059 PF06348.11 CDS30398.1 - 0.16 12.2 1.4 2 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-met PF12874.7 CDS30398.1 - 0.55 10.7 0.1 0.55 10.7 0.1 8.4 9 1 0 9 9 9 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 CDS30398.1 - 0.76 10.0 0.0 0.76 10.0 0.0 4.4 3 2 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) 7TM_GPCR_Srw PF10324.9 CDS30399.1 - 1.3e-05 24.7 0.8 1.9e-05 24.1 0.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS30399.1 - 1.7e-05 24.3 3.6 0.00021 20.7 1.8 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS30399.1 - 0.0078 15.6 4.7 0.25 10.7 3.6 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DHHC PF01529.20 CDS30399.1 - 0.019 15.1 0.1 0.083 13.0 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase fn3 PF00041.21 CDS30401.1 - 7.2e-13 48.7 13.4 6.1e-09 36.1 0.2 5.5 5 2 0 5 5 5 2 Fibronectin type III domain WAP PF00095.21 CDS30401.1 - 0.0011 19.4 5.7 0.0011 19.4 5.7 3.4 4 0 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pur_ac_phosph_N PF16656.5 CDS30401.1 - 0.046 14.3 1.1 5.5 7.6 0.2 2.8 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Toxin_18 PF08087.11 CDS30401.1 - 0.05 13.6 1.3 0.22 11.6 0.3 2.4 2 0 0 2 2 2 0 Conotoxin O-superfamily DUF1754 PF08555.10 CDS30402.1 - 0.032 15.0 10.1 0.061 14.1 2.9 2.3 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1676 PF07898.13 CDS30402.1 - 0.039 14.0 0.4 0.042 13.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Peptidase_C1 PF00112.23 CDS30403.1 - 1.5e-79 267.1 0.0 2e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CDS30403.1 - 0.0012 17.7 0.9 0.34 9.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 CDS30403.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) V-SNARE PF05008.15 CDS30404.1 - 6.8e-20 71.2 1.8 6.8e-20 71.2 1.8 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CDS30404.1 - 8.9e-17 61.1 5.4 7.8e-16 58.1 3.5 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDS30404.1 - 6.8e-05 22.7 0.6 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 Sec20 DHC_N1 PF08385.12 CDS30404.1 - 0.019 13.6 0.1 0.033 12.8 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 OppC_N PF12911.7 CDS30404.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Choline_transpo PF04515.12 CDS30404.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Sec34 PF04136.15 CDS30404.1 - 0.11 12.4 0.5 1 9.2 0.4 2.1 2 0 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.8 CDS30404.1 - 0.55 10.5 6.0 0.68 10.2 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3391 PF11871.8 CDS30404.1 - 1.9 9.0 5.0 6.5 7.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Exonuc_VII_L PF02601.15 CDS30404.1 - 1.9 8.0 4.5 6.9 6.1 4.5 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Epimerase PF01370.21 CDS30405.1 - 4e-53 180.4 0.0 5.6e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDS30405.1 - 2.5e-13 50.1 0.0 5.5e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDS30405.1 - 7.2e-06 25.3 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CDS30405.1 - 0.00011 21.3 0.2 0.00073 18.6 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDS30405.1 - 0.0058 15.8 0.9 0.021 14.0 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein ThiF PF00899.21 CDS30405.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_4 PF07993.12 CDS30405.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Male sterility protein FtsJ PF01728.19 CDS30406.1 - 1.1e-64 217.8 0.0 1.5e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-C2H2 PF00096.26 CDS30407.1 - 1.3e-15 56.9 25.2 0.0002 21.6 0.3 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS30407.1 - 4.2e-13 49.1 21.1 8.4e-06 26.0 0.9 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS30407.1 - 4.2e-10 39.6 21.4 0.03 15.2 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CDS30407.1 - 0.029 14.5 6.8 3.8 7.6 0.0 3.2 1 1 1 3 3 3 0 Aberrant zinc-finger Raffinose_syn PF05691.12 CDS30407.1 - 0.068 10.9 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 IBR PF01485.21 CDS30407.1 - 0.28 11.4 6.9 2.8 8.2 6.9 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-CGNR PF11706.8 CDS30407.1 - 0.37 10.7 6.4 9.2 6.2 0.5 3.4 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_6 PF13912.6 CDS30407.1 - 0.39 10.8 14.8 2.8 8.0 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS30407.1 - 0.46 10.3 3.9 5.6 6.8 0.4 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 CDS30407.1 - 3.5 8.0 8.6 4.1 7.8 2.3 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CDS30407.1 - 7.8 6.9 13.4 19 5.7 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS30407.1 - 9 6.8 6.4 31 5.1 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Glyco_transf_25 PF01755.17 CDS30408.1 - 9.3e-29 100.7 0.0 4.4e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 CDS30408.1 - 5.8e-06 26.7 1.7 7.8e-05 23.1 2.2 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Anp1 PF03452.14 CDS30408.1 - 0.00013 21.5 0.2 0.00027 20.5 0.2 1.5 1 0 0 1 1 1 1 Anp1 RRS1 PF04939.12 CDS30409.1 - 3.2e-33 114.9 16.2 3.2e-33 114.9 16.2 2.2 2 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) Ig_3 PF13927.6 CDS30410.1 - 3.7e-13 49.9 0.7 9.6e-05 22.9 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 CDS30410.1 - 2.6e-12 46.6 0.1 3.5e-06 27.0 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS30410.1 - 1.9e-08 34.5 0.2 0.57 10.6 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_4 PF16680.5 CDS30410.1 - 0.00039 20.6 0.0 0.01 16.1 0.0 2.5 2 0 0 2 2 2 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 CDS30410.1 - 0.0023 18.1 0.5 0.35 11.0 0.0 3.6 3 1 1 4 4 4 1 Immunoglobulin V-set domain ig PF00047.25 CDS30410.1 - 0.02 15.0 0.0 8 6.7 0.0 2.8 2 0 0 2 2 2 0 Immunoglobulin domain DUF2207 PF09972.9 CDS30411.1 - 0.058 12.1 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP-synt_I PF03899.15 CDS30411.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase I chain TRAM_LAG1_CLN8 PF03798.16 CDS30412.1 - 2.5e-14 53.5 3.8 2.5e-14 53.5 3.8 1.4 2 0 0 2 2 2 1 TLC domain Chromate_transp PF02417.15 CDS30412.1 - 0.13 12.4 4.8 0.19 11.9 4.8 1.3 1 1 0 1 1 1 0 Chromate transporter AAA_6 PF12774.7 CDS30413.1 - 3.2e-158 525.9 0.2 3.6e-157 522.4 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS30413.1 - 1.3e-137 459.2 8.6 1.3e-137 459.2 8.6 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CDS30413.1 - 5.2e-99 330.8 0.2 5.2e-99 330.8 0.2 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS30413.1 - 3.4e-89 297.7 5.3 2.2e-87 291.8 0.1 4.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS30413.1 - 2.3e-79 265.1 0.1 1.8e-75 252.5 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS30413.1 - 1.8e-47 161.2 0.2 1.8e-46 158.0 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDS30413.1 - 1.1e-46 157.8 0.0 1.8e-45 153.9 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDS30413.1 - 2e-44 152.0 2.3 3.2e-44 151.4 2.3 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CDS30413.1 - 5e-25 88.1 0.4 2.5e-24 85.8 0.4 2.4 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CDS30413.1 - 3.5e-18 65.7 0.1 2.2e-17 63.1 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CDS30413.1 - 1.4e-16 60.7 0.0 8.2e-06 25.9 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS30413.1 - 9.8e-06 25.9 0.4 0.46 10.8 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 CDS30413.1 - 4.4e-05 23.9 0.0 0.35 11.3 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDS30413.1 - 5.7e-05 23.7 1.0 0.054 14.0 0.0 3.9 4 0 0 4 4 2 1 AAA domain T2SSE PF00437.20 CDS30413.1 - 0.0024 17.0 1.6 0.43 9.6 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_16 PF13191.6 CDS30413.1 - 0.0064 16.9 3.3 37 4.6 0.0 5.2 5 0 0 5 5 4 0 AAA ATPase domain Ribonuc_P_40 PF08584.11 CDS30413.1 - 0.0093 15.3 0.0 0.028 13.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_helicase PF00910.22 CDS30413.1 - 0.016 15.6 0.1 19 5.7 0.0 3.9 3 0 0 3 3 3 0 RNA helicase DUF853 PF05872.12 CDS30413.1 - 0.02 13.5 1.1 1.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 CDS30413.1 - 0.026 14.3 0.1 3.6 7.3 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDS30413.1 - 0.03 13.7 0.1 1.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Bacillus_HBL PF05791.11 CDS30413.1 - 0.038 13.8 0.3 0.19 11.6 0.0 2.4 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_30 PF13604.6 CDS30413.1 - 0.07 12.8 0.1 13 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain MADF_DNA_bdg PF10545.9 CDS30413.1 - 0.23 11.8 1.7 1.2 9.5 1.7 2.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like STAT_alpha PF01017.20 CDS30413.1 - 5.3 6.9 9.3 1.7 8.5 0.6 4.3 4 0 0 4 4 4 0 STAT protein, all-alpha domain eIF-6 PF01912.18 CDS30414.1 - 2.9e-79 265.0 0.4 4.8e-79 264.3 0.2 1.4 2 0 0 2 2 2 1 eIF-6 family SR-25 PF10500.9 CDS30415.1 - 0.0013 18.4 13.7 0.0013 18.4 13.7 3.0 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 CDS30416.1 - 1.7e-42 145.6 32.2 1.7e-42 145.6 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS30416.1 - 1.2e-07 30.9 6.3 1.2e-07 30.9 6.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter SNF2_N PF00176.23 CDS30417.1 - 6e-50 169.9 0.6 1.1e-49 169.1 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS30417.1 - 6.9e-18 65.0 0.0 1.6e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1086 PF06461.11 CDS30417.1 - 2.2e-17 63.2 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) CHDCT2 PF08074.11 CDS30417.1 - 6.7e-10 39.4 4.2 5.6e-07 29.9 2.5 3.0 2 1 0 2 2 2 2 CHDCT2 (NUC038) domain ResIII PF04851.15 CDS30417.1 - 1.6e-07 31.5 0.0 3.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 CDS30417.1 - 5.8e-07 29.3 0.8 0.002 18.0 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 CDS30417.1 - 6e-07 28.9 0.2 3.2e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 CDS30417.1 - 0.00076 18.8 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1087 PF06465.13 CDS30417.1 - 0.0036 17.3 0.4 0.025 14.6 0.4 2.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) TniB PF05621.11 CDS30417.1 - 0.034 13.6 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Bestrophin PF01062.21 CDS30418.1 - 1.7e-75 254.2 3.2 2e-75 253.9 3.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 CDS30419.1 - 8.1e-63 212.5 0.1 1.1e-62 212.1 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel NADH_oxidored PF08040.11 CDS30419.1 - 0.016 14.9 0.7 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 MNLL subunit EF-hand_6 PF13405.6 CDS30420.1 - 1.9e-06 27.3 0.5 0.0063 16.4 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS30420.1 - 1.9e-05 23.9 0.2 0.17 11.5 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CDS30420.1 - 5.3e-05 23.6 0.1 6.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS30420.1 - 0.00015 21.5 0.7 0.011 15.6 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS30422.1 - 2.4e-11 42.3 0.2 1.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS30422.1 - 1.8e-10 39.9 0.2 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDS30422.1 - 4.6e-09 36.6 4.8 2.5e-06 27.8 0.9 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS30422.1 - 3e-05 23.3 0.3 0.0021 17.5 0.1 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDS30422.1 - 0.039 14.3 0.1 10 6.5 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDS30422.1 - 0.076 12.9 0.5 2.3 8.1 0.2 2.5 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 CDS30422.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CDS30423.1 - 4.4e-15 55.9 6.1 3.4e-09 37.0 1.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS30423.1 - 4.7e-13 47.7 2.2 8.5e-07 28.1 1.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS30423.1 - 7.9e-13 47.2 0.5 2.2e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS30423.1 - 4.2e-08 32.9 1.4 4.1e-07 29.7 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS30423.1 - 1.2e-07 30.9 0.9 0.00026 20.3 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 CDS30423.1 - 3.9e-06 26.6 1.4 8.7e-06 25.5 0.4 1.8 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDS30423.1 - 0.00028 21.2 0.8 0.0084 16.4 0.2 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDS30423.1 - 0.0098 15.8 0.5 0.038 13.9 0.4 1.8 1 1 1 2 2 2 1 Caleosin related protein AbiJ_NTD4 PF18863.1 CDS30423.1 - 0.023 15.2 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Sigma70_r1_1 PF03979.14 CDS30423.1 - 0.044 13.9 0.2 1.8 8.7 0.0 2.1 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 EF-hand_1 PF00036.32 CDS30424.1 - 4.6e-27 91.5 11.6 6.6e-07 28.4 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS30424.1 - 3.2e-26 89.0 9.3 1.6e-06 27.6 0.5 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CDS30424.1 - 1.5e-23 83.0 13.9 6.2e-11 42.6 0.7 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS30424.1 - 3e-19 67.6 7.8 0.00013 21.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS30424.1 - 2.3e-14 53.0 9.7 1.1e-07 31.6 0.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 CDS30424.1 - 1.4e-09 37.7 11.5 2.5e-05 24.1 0.4 3.5 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 CDS30424.1 - 4.8e-06 26.9 6.9 0.017 15.4 0.3 3.5 1 1 3 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDS30424.1 - 2.6e-05 24.2 3.3 0.13 12.2 0.3 2.9 2 2 2 4 4 4 2 Caleosin related protein DUF5092 PF17010.5 CDS30424.1 - 0.00029 20.8 1.9 0.48 10.3 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5092) MmoB_DmpM PF02406.17 CDS30424.1 - 0.0006 20.0 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 MmoB/DmpM family Sigma70_r1_1 PF03979.14 CDS30424.1 - 0.0033 17.5 2.7 2.4 8.3 0.1 3.8 2 2 2 4 4 4 1 Sigma-70 factor, region 1.1 DnaB_2 PF07261.11 CDS30424.1 - 0.015 15.1 0.3 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment AbiJ_NTD4 PF18863.1 CDS30424.1 - 0.015 15.7 1.8 0.1 13.1 0.2 2.1 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 HTH_48 PF17906.1 CDS30424.1 - 0.021 14.9 0.0 7.3 6.8 0.0 2.7 3 0 0 3 3 3 0 HTH domain in Mos1 transposase DUF1007 PF06226.13 CDS30424.1 - 0.038 14.0 0.1 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1007) EF-hand_4 PF12763.7 CDS30424.1 - 0.12 12.4 0.6 2.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RecG_N PF17190.4 CDS30424.1 - 0.16 12.7 5.8 0.34 11.7 1.5 2.4 1 1 0 2 2 2 0 RecG N-terminal helical domain Complex1_LYR_2 PF13233.6 CDS30424.1 - 0.36 11.6 4.1 9.2 7.1 0.2 2.4 1 1 1 2 2 2 0 Complex1_LYR-like EF-hand_6 PF13405.6 CDS30425.1 - 3.6e-15 54.5 3.7 6.4e-08 31.9 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS30425.1 - 7.9e-15 53.2 5.1 3.1e-08 32.6 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDS30425.1 - 1.1e-14 53.2 5.0 2.1e-09 36.4 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS30425.1 - 1.5e-11 44.6 1.9 2e-11 44.1 1.9 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS30425.1 - 9.6e-10 38.2 4.6 5.6e-07 29.3 1.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 CDS30425.1 - 0.00023 20.9 3.1 0.03 14.2 0.7 2.3 1 1 1 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CDS30425.1 - 0.00094 19.5 0.3 0.0012 19.1 0.3 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS30425.1 - 0.019 14.9 0.4 0.025 14.5 0.4 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDS30425.1 - 0.026 14.4 0.5 0.57 10.1 0.2 2.0 1 1 1 2 2 2 0 Caleosin related protein EF-hand_1 PF00036.32 CDS30426.1 - 6.2e-15 53.6 2.2 1.5e-06 27.3 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDS30426.1 - 5.6e-12 44.6 3.0 2.9e-06 26.5 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS30426.1 - 2.1e-11 42.8 3.2 2.3e-05 24.0 0.2 2.3 1 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CDS30426.1 - 4e-09 36.8 0.6 1.2e-08 35.3 0.7 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS30426.1 - 3.9e-08 33.0 2.0 0.00039 20.2 0.2 2.2 1 1 0 2 2 2 2 EF-hand domain pair EspA PF03433.13 CDS30426.1 - 0.016 15.0 0.7 4.1 7.2 0.0 2.0 1 1 1 2 2 2 0 EspA-like secreted protein SPARC_Ca_bdg PF10591.9 CDS30426.1 - 0.04 14.3 0.1 0.065 13.5 0.1 1.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1103 PF06513.11 CDS30426.1 - 0.076 12.6 0.0 0.088 12.4 0.0 1.0 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_10 PF14788.6 CDS30426.1 - 0.088 12.7 1.9 0.82 9.6 0.1 2.5 1 1 2 3 3 3 0 EF hand Sigma54_CBD PF04963.13 CDS30426.1 - 0.098 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain EF-hand_1 PF00036.32 CDS30427.1 - 7.5e-17 59.6 1.5 4.2e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDS30427.1 - 1.4e-14 52.8 1.4 3.1e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS30427.1 - 1.8e-13 50.7 0.2 2e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CDS30427.1 - 1e-12 47.7 1.4 3.4e-08 33.2 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS30427.1 - 2.6e-12 45.6 0.4 1.7e-05 24.3 0.0 2.2 2 1 0 2 2 2 2 EF-hand domain DnaI_N PF07319.11 CDS30427.1 - 0.013 16.2 0.0 0.017 15.8 0.0 1.1 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus FR47 PF08445.10 CDS30427.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 FR47-like protein DUF4315 PF14193.6 CDS30427.1 - 0.02 14.9 0.3 0.024 14.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Slx4 PF09494.10 CDS30427.1 - 0.027 14.4 0.1 0.19 11.7 0.0 1.9 1 1 1 2 2 2 0 Slx4 endonuclease SPARC_Ca_bdg PF10591.9 CDS30427.1 - 0.028 14.7 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ZipA_C PF04354.13 CDS30427.1 - 0.074 12.9 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain EF-hand_10 PF14788.6 CDS30427.1 - 0.11 12.4 1.0 11 6.0 0.2 2.5 2 1 0 2 2 2 0 EF hand MSA-2c PF12238.8 CDS30427.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c EF-hand_1 PF00036.32 CDS30428.1 - 7e-14 50.3 0.7 3e-06 26.4 0.4 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS30428.1 - 3.2e-12 45.4 1.3 9e-06 25.2 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS30428.1 - 5.3e-10 39.0 1.3 4.4e-05 23.2 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS30428.1 - 1.4e-09 37.0 1.3 0.00097 18.5 0.3 2.4 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS30428.1 - 1.3e-08 35.2 0.7 0.0016 18.8 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 CDS30428.1 - 0.00024 20.9 0.3 0.00067 19.5 0.1 1.8 1 1 1 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDS30428.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region PaaX PF07848.12 CDS30428.1 - 0.011 15.9 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein EF-hand_9 PF14658.6 CDS30428.1 - 0.074 13.4 0.0 0.09 13.1 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EspA PF03433.13 CDS30428.1 - 0.082 12.7 0.2 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 EspA-like secreted protein DUF1007 PF06226.13 CDS30428.1 - 0.085 12.8 0.3 0.67 9.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1007) EF-hand_7 PF13499.6 CDS30429.1 - 0.00031 21.1 0.1 0.00043 20.7 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS30429.1 - 0.0033 17.2 0.2 0.038 13.9 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain EF-G-binding_N PF07299.11 CDS30429.1 - 0.044 14.3 0.1 0.096 13.2 0.0 1.5 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FtsZ_C PF12327.8 CDS30429.1 - 0.047 14.0 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 FtsZ family, C-terminal domain EF-hand_1 PF00036.32 CDS30429.1 - 0.095 12.3 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Beta-lactamase2 PF13354.6 CDS30429.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family HTH_48 PF17906.1 CDS30431.1 - 1.2e-07 31.8 0.1 2.8e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase PolyG_pol PF01518.16 CDS30431.1 - 0.0085 14.8 1.3 1.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Sigma NS protein PFU PF09070.11 CDS30432.1 - 2.9e-37 127.4 0.0 5e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CDS30432.1 - 6.5e-27 93.3 21.6 2.5e-06 28.1 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.11 CDS30432.1 - 1.1e-20 74.0 1.3 1.8e-20 73.4 1.3 1.2 1 0 0 1 1 1 1 PUL domain Pox_A14 PF05767.12 CDS30433.1 - 0.0099 16.0 5.6 0.0099 16.0 5.6 2.0 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 LtrA PF06772.11 CDS30433.1 - 0.016 14.4 6.2 0.02 14.1 6.2 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF1453 PF07301.11 CDS30433.1 - 0.023 14.7 1.0 0.023 14.7 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) DUF2976 PF11190.8 CDS30433.1 - 0.033 14.0 3.4 0.27 11.0 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Gaa1 PF04114.14 CDS30433.1 - 0.071 12.1 6.3 0.082 11.9 6.3 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component MIG-14_Wnt-bd PF06664.12 CDS30433.1 - 0.076 12.2 8.0 0.094 11.9 8.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Cyt_bd_oxida_II PF02322.15 CDS30433.1 - 0.097 12.0 9.1 0.13 11.6 9.1 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II SPC12 PF06645.13 CDS30433.1 - 0.14 12.3 0.4 0.14 12.3 0.4 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HisKA_7TM PF16927.5 CDS30433.1 - 0.18 11.8 7.8 0.33 10.9 7.8 1.4 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase PIG-U PF06728.13 CDS30433.1 - 0.24 10.4 6.3 0.31 10.0 6.3 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF2070 PF09843.9 CDS30433.1 - 2.4 6.4 6.1 2.1 6.5 1.3 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Virul_fac_BrkB PF03631.15 CDS30433.1 - 2.4 7.7 12.1 0.068 12.8 4.7 1.8 1 1 1 2 2 2 0 Virulence factor BrkB DUF2207 PF09972.9 CDS30433.1 - 6.9 5.3 12.2 5 5.8 3.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Intg_mem_TP0381 PF09529.10 CDS30433.1 - 7.1 6.1 12.3 0.96 8.9 7.2 1.8 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) La PF05383.17 CDS30435.1 - 4e-20 71.6 2.0 2.2e-19 69.3 0.5 2.3 2 0 0 2 2 2 1 La domain FRQ PF09421.10 CDS30435.1 - 0.014 13.4 0.0 0.027 12.5 0.0 1.4 1 0 0 1 1 1 0 Frequency clock protein DUF3435 PF11917.8 CDS30435.1 - 0.034 13.1 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) SusE PF14292.6 CDS30435.1 - 0.064 13.5 0.6 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 SusE outer membrane protein Rotamase PF00639.21 CDS30436.1 - 7.8e-25 87.7 0.0 9.6e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDS30436.1 - 5.7e-23 81.7 0.0 6.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CDS30436.1 - 3e-12 46.4 0.8 6.4e-12 45.4 0.3 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 CDS30436.1 - 1.8e-05 25.6 0.0 2.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain GDA1_CD39 PF01150.17 CDS30437.1 - 9.8e-52 176.0 0.0 7.3e-46 156.7 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Transposase_1 PF01359.18 CDS30438.1 - 6.1e-11 42.0 0.1 2.6e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) zf-H2C2_2 PF13465.6 CDS30439.2 - 2.9e-29 100.1 36.0 5.2e-08 33.0 0.7 6.4 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30439.2 - 1.1e-26 91.7 40.6 4.6e-07 29.9 0.8 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30439.2 - 3.9e-16 58.4 34.2 0.00013 22.5 0.4 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS30439.2 - 1.5e-08 34.7 19.0 0.34 11.3 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS30439.2 - 4.9e-06 26.2 22.1 0.086 12.6 0.0 5.5 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-met PF12874.7 CDS30439.2 - 2e-05 24.8 29.5 1.3 9.5 1.5 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CDS30439.2 - 0.0027 17.3 13.1 7.6 6.2 0.1 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Rep_fac-A_C PF08646.10 CDS30439.2 - 0.0044 16.8 7.7 0.79 9.5 0.1 3.3 1 1 2 3 3 3 2 Replication factor-A C terminal domain zinc_ribbon_15 PF17032.5 CDS30439.2 - 0.0064 17.2 13.6 0.38 11.5 1.8 3.4 2 1 3 5 5 4 2 zinc-ribbon family DUF3268 PF11672.8 CDS30439.2 - 0.015 15.6 12.2 1.1 9.6 0.3 3.5 3 1 1 4 4 4 0 zinc-finger-containing domain zf-trcl PF13451.6 CDS30439.2 - 0.044 13.7 17.5 1.8 8.5 2.3 5.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain zf_ZIC PF18366.1 CDS30439.2 - 0.044 13.9 9.3 0.11 12.6 0.5 3.6 1 1 2 3 3 3 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 CDS30439.2 - 0.051 13.7 28.3 0.72 10.0 3.5 4.7 2 2 2 4 4 4 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 CDS30439.2 - 0.067 13.0 34.6 0.21 11.4 1.1 6.6 5 1 0 5 5 5 0 C2H2-type zinc-finger domain HypA PF01155.19 CDS30439.2 - 0.11 12.5 14.0 0.98 9.5 1.2 3.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 CDS30439.2 - 0.2 11.7 18.4 0.1 12.7 2.0 3.2 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C2HE PF16278.5 CDS30439.2 - 0.2 12.1 28.9 5.2 7.6 1.4 5.3 2 2 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 CDS30439.2 - 0.21 11.8 19.4 0.51 10.6 0.8 4.2 2 1 2 4 4 4 0 LIM domain zf-C2H2_6 PF13912.6 CDS30439.2 - 0.24 11.5 35.8 0.37 10.8 0.5 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger Trm112p PF03966.16 CDS30439.2 - 0.32 11.6 6.2 7.2 7.3 0.0 3.7 3 1 0 3 3 3 0 Trm112p-like protein PHD PF00628.29 CDS30439.2 - 0.35 10.8 18.4 0.18 11.7 2.1 3.2 3 0 0 3 3 3 0 PHD-finger CpXC PF14353.6 CDS30439.2 - 0.35 10.9 14.1 5.4 7.1 0.0 4.7 1 1 2 4 4 4 0 CpXC protein XPA_N PF01286.18 CDS30439.2 - 0.49 10.5 17.4 1.9 8.6 0.1 5.0 5 0 0 5 5 5 0 XPA protein N-terminal zf-AN1 PF01428.16 CDS30439.2 - 0.55 10.4 26.0 11 6.3 0.1 5.3 4 1 1 5 5 5 0 AN1-like Zinc finger zf-RING_7 PF02591.15 CDS30439.2 - 0.81 9.9 18.0 2.7 8.3 0.9 4.8 5 0 0 5 5 5 0 C4-type zinc ribbon domain Metallothio_Pro PF02069.16 CDS30439.2 - 0.82 9.9 13.5 9.1 6.6 2.4 3.8 3 1 0 3 3 3 0 Prokaryotic metallothionein ADK_lid PF05191.14 CDS30439.2 - 0.86 9.6 12.3 3.3 7.8 0.6 4.4 2 1 3 5 5 5 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 CDS30439.2 - 1.2 9.4 15.7 2 8.8 0.1 4.8 4 1 1 5 5 5 0 zinc-ribbon Sprouty PF05210.13 CDS30439.2 - 1.4 9.4 8.1 4.9 7.6 0.4 2.4 2 0 0 2 2 2 0 Sprouty protein (Spry) Zn_ribbon_recom PF13408.6 CDS30439.2 - 6.9 7.3 21.0 51 4.5 0.1 4.7 3 2 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-C3HC4_2 PF13923.6 CDS30441.2 - 3.4e-12 46.0 10.7 3.4e-12 46.0 10.7 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS30441.2 - 5e-11 42.8 10.5 5e-11 42.8 10.5 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS30441.2 - 3.8e-10 39.6 8.7 3.8e-10 39.6 8.7 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS30441.2 - 5.8e-10 38.9 10.9 5.8e-10 38.9 10.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS30441.2 - 1.4e-09 37.6 7.8 1.4e-09 37.6 7.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS30441.2 - 5.5e-08 32.6 7.9 5.5e-08 32.6 7.9 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDS30441.2 - 1.3e-07 31.6 10.4 1.3e-07 31.6 10.4 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDS30441.2 - 1.9e-07 30.9 3.6 1.9e-07 30.9 3.6 2.3 1 1 1 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CDS30441.2 - 4.4e-06 26.5 9.6 4.4e-06 26.5 9.6 3.0 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDS30441.2 - 3.2e-05 24.1 10.5 3.2e-05 24.1 10.5 3.1 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 CDS30441.2 - 0.0048 16.7 7.5 0.015 15.1 7.5 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CDS30441.2 - 0.02 15.1 0.1 0.05 13.8 0.1 1.7 1 0 0 1 1 1 0 U-box domain DUF87 PF01935.17 CDS30441.2 - 0.063 13.4 0.8 0.09 12.9 0.8 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain HTH_Tnp_Tc3_1 PF11427.8 CDS30441.2 - 0.11 12.4 0.3 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Tc3 transposase DZR PF12773.7 CDS30441.2 - 0.18 11.9 17.4 0.072 13.1 4.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon DUF4239 PF14023.6 CDS30441.2 - 0.24 11.1 0.5 0.5 10.1 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) zf-ANAPC11 PF12861.7 CDS30441.2 - 0.38 10.8 13.6 0.21 11.6 4.4 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 CDS30441.2 - 0.4 10.7 20.8 0.43 10.6 5.8 2.6 1 1 0 2 2 2 0 zinc-ribbons T6PP_N PF18572.1 CDS30441.2 - 0.83 9.5 4.4 0.79 9.6 2.8 1.8 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1258 PF06869.12 CDS30441.2 - 2.8 7.3 9.2 0.31 10.5 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Mito_carr PF00153.27 CDS30443.1 - 6.5e-57 189.5 7.2 2.4e-18 65.8 0.0 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein KxDL PF10241.9 CDS30444.1 - 1.6e-21 76.3 3.5 3.6e-21 75.2 3.5 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein Cation_efflux PF01545.21 CDS30444.1 - 2.3e-14 53.6 14.3 4.4e-14 52.7 14.3 1.5 1 1 0 1 1 1 1 Cation efflux family HsbA PF12296.8 CDS30444.1 - 0.0022 18.4 0.9 0.0062 17.0 0.8 1.9 1 1 0 1 1 1 1 Hydrophobic surface binding protein A CCDC144C PF14915.6 CDS30444.1 - 0.0058 15.8 4.4 0.0092 15.1 4.4 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Herpes_BLRF2 PF05812.12 CDS30444.1 - 0.024 14.8 2.2 0.04 14.1 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Snapin_Pallidin PF14712.6 CDS30444.1 - 0.036 14.5 8.5 0.085 13.3 8.5 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Phage_Nu1 PF07471.12 CDS30444.1 - 0.19 11.5 0.2 1.3 8.7 0.3 2.0 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 NPV_P10 PF05531.12 CDS30444.1 - 0.24 11.9 2.0 1.9 9.0 2.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 CDS30444.1 - 0.28 11.2 3.2 0.74 9.9 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2530 PF10745.9 CDS30444.1 - 0.79 10.0 2.2 2.8 8.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Uso1_p115_C PF04871.13 CDS30444.1 - 2.6 8.4 5.2 4.3 7.7 5.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HCNGP PF07818.13 CDS30445.1 - 1.5e-28 99.3 0.4 2.8e-28 98.4 0.4 1.4 1 0 0 1 1 1 1 HCNGP-like protein SecY PF00344.20 CDS30446.1 - 3.1e-72 243.4 13.1 4.1e-72 243.0 13.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDS30446.1 - 4.1e-16 58.5 0.1 1.1e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Transposon_TraM PF12508.8 CDS30446.1 - 0.21 11.3 0.1 0.41 10.3 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon, TraM DUF1430 PF07242.11 CDS30446.1 - 2.6 8.4 7.5 1.6 9.0 2.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) adh_short_C2 PF13561.6 CDS30447.1 - 3.5e-60 203.5 3.3 4e-60 203.3 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDS30447.1 - 6.8e-54 182.3 3.5 8.4e-54 182.0 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDS30447.1 - 1.4e-11 44.6 0.6 2e-11 44.1 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDS30447.1 - 9.6e-05 22.0 0.6 0.00024 20.6 0.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDS30447.1 - 0.036 13.2 0.1 0.071 12.2 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain YscJ_FliF PF01514.17 CDS30447.1 - 0.052 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family THF_DHG_CYH_C PF02882.19 CDS30447.1 - 0.055 12.8 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Exostosin PF03016.15 CDS30448.1 - 1.3e-23 83.7 0.1 2.3e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Exostosin family Glyco_transf_64 PF09258.10 CDS30448.1 - 6.2e-11 42.0 0.0 2.1e-09 37.0 0.0 2.3 1 1 1 2 2 2 1 Glycosyl transferase family 64 domain DUF1885 PF08968.10 CDS30448.1 - 0.045 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Stealth_CR2 PF11380.8 CDS30448.1 - 0.083 13.1 1.6 0.26 11.5 0.2 2.6 3 0 0 3 3 3 0 Stealth protein CR2, conserved region 2 BRO1 PF03097.18 CDS30451.2 - 1.1e-39 136.4 3.8 3.2e-35 121.7 4.4 2.1 2 0 0 2 2 2 2 BRO1-like domain YL1 PF05764.13 CDS30451.2 - 7.4e-05 23.0 3.4 0.00014 22.0 3.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CsiV PF10972.8 CDS30451.2 - 0.02 14.6 3.4 3 7.5 3.4 2.6 1 1 0 1 1 1 0 Peptidoglycan-binding protein, CsiV DUF2452 PF10504.9 CDS30451.2 - 0.023 14.1 0.0 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2452) DUF4058 PF13267.6 CDS30453.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) zf-Tim10_DDP PF02953.15 CDS30455.1 - 3.5e-19 68.2 0.5 4.3e-19 67.9 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger UCH PF00443.29 CDS30457.1 - 3.7e-50 170.8 0.4 6.2e-50 170.1 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS30457.1 - 1.6e-24 87.1 6.6 3.1e-24 86.2 6.6 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 CDS30457.1 - 0.2 11.0 1.6 16 4.9 0.1 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Frizzled PF01534.17 CDS30458.1 - 1.3e-20 73.7 6.1 9.2e-15 54.5 2.8 2.4 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region Fz PF01392.22 CDS30458.1 - 1.5e-06 28.8 0.0 1.4e-05 25.6 0.0 2.4 1 1 1 2 2 2 1 Fz domain LRR_4 PF12799.7 CDS30462.2 - 3.2e-06 27.4 1.0 3.2e-06 27.4 1.0 4.9 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDS30462.2 - 3.6e-05 23.5 3.0 0.14 12.3 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.6 CDS30462.2 - 0.052 13.3 0.3 0.052 13.3 0.3 4.8 3 2 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 CDS30462.2 - 9.8 7.2 18.1 12 6.9 0.2 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat zf-C2H2 PF00096.26 CDS30463.1 - 1.3e-36 123.0 42.9 1.2e-05 25.5 0.4 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30463.1 - 5e-29 98.5 43.6 0.00022 21.8 1.7 7.2 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS30463.1 - 1.8e-22 78.7 37.7 2.2e-05 24.7 0.1 8.0 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS30463.1 - 3.3e-13 49.5 32.8 0.013 15.8 0.8 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS30463.1 - 3.6e-13 49.4 27.6 0.055 13.9 0.1 7.3 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CDS30463.1 - 1.8e-08 35.1 18.9 0.23 12.1 0.4 5.6 1 1 2 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDS30463.1 - 2.1e-08 33.9 44.6 0.024 14.6 1.3 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS30463.1 - 1.4e-06 27.9 27.2 0.074 12.8 0.2 6.5 6 0 0 6 6 6 2 zinc-finger C2H2-type zf-Di19 PF05605.12 CDS30463.1 - 1.5e-06 28.4 26.0 0.0068 16.7 2.1 5.1 2 2 2 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDS30463.1 - 1e-05 25.8 27.9 0.41 11.0 0.3 6.7 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CDS30463.1 - 0.00095 19.4 24.5 0.017 15.4 2.2 4.3 1 1 3 4 4 4 2 C2H2-type zinc ribbon DUF629 PF04780.12 CDS30463.1 - 0.0064 15.1 25.5 1.3 7.5 0.6 5.4 1 1 6 7 7 7 3 Protein of unknown function (DUF629) zf-C2HE PF16278.5 CDS30463.1 - 0.0094 16.4 2.3 0.0094 16.4 2.3 6.3 3 3 3 7 7 7 2 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 CDS30463.1 - 0.013 15.1 24.0 0.59 9.8 0.4 6.8 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 CDS30463.1 - 0.015 15.0 47.1 0.063 13.0 1.2 8.6 7 2 0 7 7 7 0 C2H2-type zinc-finger domain HypA PF01155.19 CDS30463.1 - 0.02 14.9 19.2 0.67 10.0 1.2 4.1 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 CDS30463.1 - 0.082 13.0 21.8 3.5 7.7 1.1 5.9 1 1 5 6 6 6 0 CpXC protein PyrI_C PF02748.15 CDS30463.1 - 0.15 12.0 22.3 2.5 8.1 0.1 5.8 4 3 3 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 CDS30463.1 - 0.16 12.1 29.7 22 5.3 0.2 7.0 6 1 1 7 7 7 0 AN1-like Zinc finger TRAF6_Z2 PF18048.1 CDS30463.1 - 0.19 11.8 8.5 1.1 9.4 0.5 4.2 5 0 0 5 5 4 0 TNF receptor-associated factor 6 zinc finger 2 GATA PF00320.27 CDS30463.1 - 0.23 11.1 0.2 0.23 11.1 0.2 3.6 4 0 0 4 4 3 0 GATA zinc finger FYDLN_acid PF09538.10 CDS30463.1 - 0.24 12.1 6.0 1.8 9.3 0.0 3.8 3 2 1 4 4 4 0 Protein of unknown function (FYDLN_acid) zf_C2H2_13 PF18508.1 CDS30463.1 - 0.26 10.9 5.0 8.2 6.1 0.1 3.7 3 0 0 3 3 3 0 Zinc finger domain Zn_ribbon_recom PF13408.6 CDS30463.1 - 0.27 11.8 19.2 21 5.7 0.1 5.6 5 1 1 6 6 6 0 Recombinase zinc beta ribbon domain Zn-C2H2_12 PF18112.1 CDS30463.1 - 0.51 10.8 0.0 0.51 10.8 0.0 5.5 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 CDS30463.1 - 0.59 10.1 0.1 0.59 10.1 0.1 6.1 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 CDS30463.1 - 1 9.5 11.3 12 6.1 0.2 4.9 3 2 2 5 5 5 0 Zic proteins zinc finger domain PHD_Oberon PF07227.11 CDS30463.1 - 1.1 9.1 16.2 1.8 8.5 9.9 3.2 1 1 2 3 3 3 0 PHD - plant homeodomain finger protein zf-BED PF02892.15 CDS30463.1 - 1.1 9.3 40.7 2.2 8.4 1.6 6.4 3 2 3 6 6 5 0 BED zinc finger Zn-ribbon_8 PF09723.10 CDS30463.1 - 1.2 9.3 32.4 1.3 9.2 2.7 6.4 3 2 4 7 7 7 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 CDS30463.1 - 1.2 8.8 30.7 2 8.1 1.9 6.2 3 2 4 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 CDS30463.1 - 1.3 9.3 32.2 3.3 8.0 1.6 6.4 2 2 3 5 5 5 0 LIM domain ARS2 PF04959.13 CDS30463.1 - 1.6 9.0 18.3 0.26 11.7 0.6 3.3 2 2 2 4 4 4 0 Arsenite-resistance protein 2 zf-C2H2_9 PF16293.5 CDS30463.1 - 1.8 8.5 13.7 29 4.6 0.0 5.9 6 1 1 7 7 7 0 C2H2 type zinc-finger (1 copy) ADK_lid PF05191.14 CDS30463.1 - 2.9 7.9 14.5 1.1 9.2 0.5 4.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-LYAR PF08790.11 CDS30463.1 - 7.9 6.5 25.0 0.93 9.5 0.4 6.0 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger I-EGF_1 PF18372.1 CDS30463.1 - 9.1 6.5 14.6 5.3 7.2 0.4 3.9 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 Med19 PF10278.9 CDS30464.1 - 1e-24 87.5 0.1 1e-24 87.5 0.1 2.2 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 Helicase_C PF00271.31 CDS30465.1 - 3e-30 104.8 0.0 6.9e-28 97.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDS30465.1 - 1.9e-28 99.4 0.1 2.5e-27 95.8 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase UTP25 PF06862.12 CDS30465.1 - 0.00011 21.2 0.0 0.00022 20.1 0.0 1.5 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 CDS30465.1 - 0.00019 20.7 0.0 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CDS30465.1 - 0.00059 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDS30465.1 - 0.012 14.9 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Tektin PF03148.14 CDS30467.1 - 3.4e-75 253.2 15.4 3.8e-75 253.0 15.4 1.0 1 0 0 1 1 1 1 Tektin family EspB_PE PF18625.1 CDS30467.1 - 0.057 13.9 0.2 0.2 12.1 0.2 1.9 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Baculo_PEP_C PF04513.12 CDS30467.1 - 0.063 13.3 3.3 4.6 7.3 0.0 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2315 PF10231.9 CDS30467.1 - 0.071 13.2 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Apoptogenic protein 1 E2F_CC-MB PF16421.5 CDS30467.1 - 0.13 12.7 1.3 0.35 11.3 0.4 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF724 PF05266.14 CDS30467.1 - 0.15 11.8 5.9 0.28 11.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PMT2_N PF17987.1 CDS30467.1 - 0.16 12.2 4.3 2 8.6 0.8 2.7 2 1 1 3 3 3 0 Phosphoethanolamine N-methyltransferase 2 N-terminal ApoLp-III PF07464.11 CDS30467.1 - 0.16 12.0 3.6 0.45 10.6 0.8 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Mer2 PF09074.10 CDS30467.1 - 0.21 11.4 8.4 0.034 14.0 4.1 1.7 2 0 0 2 2 2 0 Mer2 FUSC PF04632.12 CDS30467.1 - 0.51 8.8 2.6 0.66 8.4 1.2 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CDS30467.1 - 0.62 10.1 9.3 0.13 12.3 0.6 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) LOH1CR12 PF10158.9 CDS30467.1 - 1.1 9.3 6.7 12 5.9 0.1 3.2 3 1 1 4 4 4 0 Tumour suppressor protein YabA PF06156.13 CDS30467.1 - 1.4 9.6 10.8 5.7 7.6 0.2 4.3 3 1 1 4 4 4 0 Initiation control protein YabA YtxH PF12732.7 CDS30467.1 - 2.7 8.6 6.3 54 4.4 2.4 3.5 2 1 0 2 2 2 0 YtxH-like protein FlxA PF14282.6 CDS30467.1 - 3.1 7.8 6.7 20 5.2 1.5 2.6 2 0 0 2 2 2 0 FlxA-like protein PNP_UDP_1 PF01048.20 CDS30468.1 - 1.8e-28 99.4 0.0 2.2e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ATG11 PF10377.9 CDS30471.1 - 3.5e-09 36.8 0.0 1.4e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 11 ING PF12998.7 CDS30471.1 - 0.032 14.8 0.6 0.19 12.4 0.6 2.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding TTRAP PF14203.6 CDS30471.1 - 0.3 11.1 1.7 23 5.0 0.0 3.3 2 1 0 2 2 2 0 Putative tranposon-transfer assisting protein Homeobox_KN PF05920.11 CDS30473.1 - 1.7e-12 47.0 0.0 4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS30473.1 - 1.4e-06 28.1 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDS30473.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HLH PF00010.26 CDS30474.1 - 0.0015 18.5 0.4 0.0035 17.3 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Homeobox_KN PF05920.11 CDS30475.1 - 6e-05 22.9 0.1 0.00013 21.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox_KN PF05920.11 CDS30476.1 - 8.5e-17 60.8 0.3 8.5e-17 60.8 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CDS30476.1 - 3.8e-09 36.3 0.9 7e-09 35.4 0.9 1.4 1 0 0 1 1 1 1 Homeodomain Tubulin PF00091.25 CDS30477.1 - 5.4e-63 212.8 0.0 8e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS30477.1 - 1.7e-40 138.1 0.0 2.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS30477.1 - 0.0015 18.3 0.0 0.0039 16.9 0.0 1.6 1 1 0 1 1 1 1 Tubulin domain PKD_channel PF08016.12 CDS30480.1 - 1.1e-126 423.0 13.4 1.8e-126 422.3 13.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CDS30480.1 - 7.7e-23 81.0 29.0 7.7e-23 81.0 29.0 1.9 2 0 0 2 2 2 1 Ion transport protein Orai-1 PF07856.12 CDS30480.1 - 0.0064 16.2 3.3 0.0064 16.2 3.3 2.1 3 0 0 3 3 3 1 Mediator of CRAC channel activity EF-hand_7 PF13499.6 CDS30480.1 - 0.021 15.3 1.8 0.028 14.9 0.3 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 CDS30480.1 - 0.057 13.0 0.1 0.21 11.2 0.1 2.1 1 0 0 1 1 1 0 EF hand Baculo_PEP_C PF04513.12 CDS30480.1 - 0.23 11.5 3.3 2.4 8.2 0.3 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YgaB PF14182.6 CDS30480.1 - 4.6 7.7 9.6 2 8.8 0.4 3.0 3 0 0 3 3 3 0 YgaB-like protein DUF21 PF01595.20 CDS30480.1 - 9.5 5.9 10.9 20 4.8 0.0 3.5 3 1 1 4 4 4 0 Cyclin M transmembrane N-terminal domain Ank_2 PF12796.7 CDS30481.1 - 5.1e-10 39.8 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30481.1 - 4.6e-09 36.7 0.0 1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS30481.1 - 1.6e-08 34.7 0.5 2.9e-06 27.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS30481.1 - 3.2e-07 30.1 0.1 0.036 14.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDS30481.1 - 5.5e-06 26.6 0.0 0.02 15.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Na_K-ATPase PF00287.18 CDS30482.1 - 7.2e-39 133.6 0.1 1.1e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain 7tm_2 PF00002.24 CDS30482.1 - 0.046 13.0 0.0 3.5 6.8 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) FeS_assembly_P PF01883.19 CDS30483.1 - 9.5e-15 54.5 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Paf67 PF10255.9 CDS30484.1 - 1.1e-142 475.8 0.4 1.7e-142 475.2 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ANAPC3 PF12895.7 CDS30484.1 - 0.031 14.5 0.1 0.092 13.0 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDS30484.1 - 0.045 13.9 0.1 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TFR_dimer PF04253.15 CDS30484.1 - 0.21 11.7 0.6 4 7.6 0.1 2.6 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain SAP18 PF06487.12 CDS30485.1 - 4e-14 53.0 0.0 7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) SSB PF00436.25 CDS30486.1 - 4.5e-08 33.1 0.0 6.6e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Single-strand binding protein family Neur_chan_LBD PF02931.23 CDS30487.1 - 1.6e-48 165.0 1.8 2.1e-48 164.6 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS30487.1 - 9.4e-25 88.1 3.1 1.2e-21 77.9 0.4 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4026 PF13218.6 CDS30488.1 - 0.041 12.9 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) 2OG-FeII_Oxy_4 PF13661.6 CDS30489.1 - 4.7e-22 78.5 0.0 7e-20 71.5 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 CDS30489.1 - 1.4e-21 77.0 0.0 4.8e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.6 CDS30489.1 - 3e-13 50.5 0.0 1.8e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 CDS30489.1 - 1.1 8.5 3.1 1.9 7.7 3.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF498 PF04430.14 CDS30490.1 - 8e-19 67.7 0.0 9.2e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Kindlin_2_N PF18124.1 CDS30492.1 - 5.4e-20 71.4 0.1 1.7e-19 69.8 0.1 1.9 1 1 0 1 1 1 1 Kindlin-2 N-terminal domain FERM_M PF00373.18 CDS30492.1 - 2.1e-18 66.8 0.0 9.8e-17 61.4 0.0 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.10 CDS30492.1 - 0.0044 16.9 0.0 0.039 13.9 0.0 2.4 1 1 0 1 1 1 1 FERM N-terminal domain PH PF00169.29 CDS30492.1 - 0.016 15.7 0.0 0.056 14.0 0.0 1.9 1 1 0 1 1 1 0 PH domain zf_C2H2_ZHX PF18387.1 CDS30492.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Mid2 PF04478.12 CDS30494.1 - 0.2 11.5 0.5 0.29 10.9 0.5 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Motile_Sperm PF00635.26 CDS30495.1 - 1.3e-48 163.3 0.7 1.7e-28 98.6 0.2 2.1 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 CDS30495.1 - 1.7e-05 24.9 4.0 0.064 13.5 0.3 2.4 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CCDC92 PF14916.6 CDS30495.1 - 0.00013 21.6 0.9 0.00024 20.8 0.9 1.3 1 0 0 1 1 1 1 Coiled-coil domain of unknown function fn3_5 PF06280.12 CDS30495.1 - 0.0043 17.7 0.7 0.35 11.6 0.0 2.7 2 1 0 2 2 2 1 Fn3-like domain CDC48_2 PF02933.17 CDS30495.1 - 0.013 15.2 2.0 0.6 9.9 0.1 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF5001 PF16392.5 CDS30495.1 - 0.016 15.1 2.4 0.16 11.9 0.6 2.8 2 1 1 3 3 3 0 Ig-like domain DUF756 PF05506.12 CDS30495.1 - 0.017 16.0 0.0 0.47 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF756) ZapB PF06005.12 CDS30495.1 - 0.056 13.9 0.1 0.091 13.2 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 CDS30495.1 - 0.15 11.8 0.5 0.39 10.5 0.5 1.6 1 0 0 1 1 1 0 Septum formation initiator NYD-SP28_assoc PF14775.6 CDS30495.1 - 0.18 11.9 1.0 0.41 10.8 1.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF11 PF01345.18 CDS30495.1 - 0.31 11.3 1.9 0.68 10.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF11 EF-hand_4 PF12763.7 CDS30496.1 - 1.5e-12 47.4 0.0 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDS30496.1 - 0.0019 17.6 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 EF hand HALZ PF02183.18 CDS30496.1 - 0.042 14.1 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28 PF14772.6 CDS30496.1 - 0.043 13.9 0.3 0.073 13.1 0.3 1.3 1 0 0 1 1 1 0 Sperm tail GAS PF13851.6 CDS30497.1 - 2.7e-46 157.5 23.4 2.7e-46 157.5 23.4 3.5 2 2 1 3 3 3 1 Growth-arrest specific micro-tubule binding BNIP2 PF12496.8 CDS30497.1 - 1 9.8 4.3 3 8.3 4.2 2.1 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2207 PF09972.9 CDS30497.1 - 7.9 5.1 8.3 1.9 7.2 4.6 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) TMEM208_SND2 PF05620.11 CDS30498.1 - 1.3e-41 142.2 0.1 1.6e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 SieB PF14163.6 CDS30498.1 - 0.19 11.2 2.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B Tektin PF03148.14 CDS30499.1 - 2.3e-116 388.7 25.9 2.6e-116 388.5 25.9 1.0 1 0 0 1 1 1 1 Tektin family SYCE1 PF15233.6 CDS30499.1 - 0.022 14.8 1.7 0.022 14.8 1.7 3.1 3 1 1 4 4 4 0 Synaptonemal complex central element protein 1 Sec8_exocyst PF04048.14 CDS30499.1 - 0.033 14.1 3.4 0.22 11.4 0.3 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF812 PF05667.11 CDS30499.1 - 0.053 12.4 16.7 0.011 14.7 6.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Prefoldin PF02996.17 CDS30499.1 - 0.17 11.8 8.6 16 5.4 0.0 3.8 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 CDS30499.1 - 0.39 10.8 6.8 0.075 13.1 1.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CdvA PF18822.1 CDS30499.1 - 0.55 10.1 10.6 0.34 10.8 1.5 3.8 3 1 0 3 3 3 0 CdvA-like coiled-coil domain ATG16 PF08614.11 CDS30499.1 - 0.7 10.1 14.3 0.16 12.2 3.5 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 CDS30499.1 - 0.77 9.3 9.9 0.032 13.8 1.4 2.9 2 2 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_22 PF18833.1 CDS30499.1 - 2.9 8.1 6.6 18 5.5 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.11 CDS30499.1 - 3.6 8.2 20.0 5.4 7.6 2.5 4.7 2 2 1 3 3 3 0 Syntaxin 6, N-terminal Erp_C PF06780.11 CDS30499.1 - 3.7 7.6 7.4 2.6 8.1 0.4 3.4 2 1 1 3 3 3 0 Erp protein C-terminus TMPIT PF07851.13 CDS30499.1 - 7.5 5.7 11.2 0.17 11.1 2.7 2.2 2 1 1 3 3 3 0 TMPIT-like protein Exonuc_VII_L PF02601.15 CDS30499.1 - 8.4 5.9 12.6 0.95 9.0 6.3 2.0 1 1 0 2 2 2 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 CDS30499.1 - 8.7 6.6 14.7 0.33 11.2 4.1 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3336 PF11815.8 CDS30499.1 - 9.4 5.9 9.5 0.55 10.0 1.1 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF3336) LRR_8 PF13855.6 CDS30500.1 - 1.1e-28 98.8 24.6 1.1e-10 41.1 6.1 5.1 5 1 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CDS30500.1 - 2.1e-11 43.9 30.2 0.00015 22.1 0.0 6.0 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS30500.1 - 3.2e-05 23.9 20.5 3.4 8.6 0.0 8.5 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 CDS30500.1 - 0.00021 20.8 8.1 0.15 11.6 0.1 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 CDS30500.1 - 0.0023 17.9 0.0 0.2 11.6 0.0 2.8 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CDS30500.1 - 0.084 13.0 15.9 8.2 6.8 0.1 7.1 7 0 0 7 7 7 0 Leucine Rich repeat DUF2203 PF09969.9 CDS30501.1 - 0.38 11.5 3.7 4 8.2 3.3 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SpmSyn_N PF17950.1 CDS30501.1 - 0.7 10.1 3.5 0.44 10.8 0.2 2.3 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal FTCD_C PF04961.12 CDS30501.1 - 1.4 8.7 6.0 4.5 7.0 1.1 2.5 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF2205 PF10224.9 CDS30501.1 - 2.2 8.3 12.0 1.2 9.2 1.2 3.9 2 2 2 4 4 4 0 Short coiled-coil protein IBR PF01485.21 CDS30504.1 - 3e-19 69.0 43.5 1.2e-10 41.4 6.6 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CDS30504.1 - 0.0001 22.2 1.0 0.0001 22.2 1.0 3.2 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 CDS30504.1 - 0.0011 18.9 2.9 0.0011 18.9 2.9 5.6 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDS30504.1 - 0.0024 17.7 1.4 0.0024 17.7 1.4 4.4 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS30504.1 - 0.012 15.5 0.2 0.012 15.5 0.2 4.8 4 1 1 5 5 4 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDS30504.1 - 0.02 14.7 0.2 0.02 14.7 0.2 5.9 5 1 1 6 6 6 0 Zinc finger, C3HC4 type (RING finger) Pox_A32 PF04665.12 CDS30504.1 - 0.038 13.5 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein YhfH PF14149.6 CDS30504.1 - 0.038 14.0 4.5 0.17 11.9 4.5 2.2 1 0 0 1 1 1 0 YhfH-like protein zf-C3HC4_4 PF15227.6 CDS30504.1 - 0.064 13.4 1.0 0.064 13.4 1.0 5.2 5 1 1 6 6 6 0 zinc finger of C3HC4-type, RING DUF733 PF05306.11 CDS30504.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF733) DUF4258 PF14076.6 CDS30504.1 - 0.12 12.8 0.1 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Pecanex_C PF05041.15 CDS30505.2 - 6.9e-197 650.6 0.0 4e-97 324.3 0.0 2.3 2 0 0 2 2 2 2 Pecanex protein (C-terminus) DUF4513 PF14983.6 CDS30505.2 - 0.014 15.4 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4513) Ogr_Delta PF04606.12 CDS30505.2 - 0.035 14.1 1.4 11 6.1 0.1 2.8 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger UBA_4 PF14555.6 CDS30505.2 - 5.2 7.0 4.9 44 4.0 0.4 2.8 2 0 0 2 2 2 0 UBA-like domain SSF PF00474.17 CDS30507.1 - 2.2e-127 425.3 29.3 6.1e-127 423.9 29.3 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family Clat_adaptor_s PF01217.20 CDS30508.1 - 1.2e-46 158.1 1.7 1.6e-46 157.8 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WH1 PF00568.23 CDS30509.1 - 1.2e-10 41.3 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CDS30509.1 - 3.6e-05 24.0 0.1 9e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Gastrin PF00918.17 CDS30509.1 - 0.1 13.6 0.0 25 5.8 0.0 2.5 2 0 0 2 2 2 0 Gastrin/cholecystokinin family NTP_transferase PF00483.23 CDS30510.1 - 2e-44 152.0 0.0 2.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CDS30510.1 - 9.6e-10 37.8 5.7 3.7e-06 26.4 0.1 3.7 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CDS30510.1 - 1.8e-08 34.9 0.0 2.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CDS30510.1 - 0.021 14.6 2.1 0.062 13.1 0.1 2.9 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 CDS30510.1 - 0.19 11.4 0.0 0.46 10.2 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LIM_bind PF01803.16 CDS30511.1 - 1.3e-37 129.7 2.9 6.8e-29 101.1 0.9 3.5 4 1 1 5 5 5 2 LIM-domain binding protein LID PF17916.1 CDS30511.1 - 7.5e-14 51.1 1.3 1.4e-13 50.2 1.3 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) Na_Ca_ex PF01699.24 CDS30513.1 - 3.7e-39 134.1 44.8 3.7e-22 78.9 19.0 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ATP-synt_S1 PF05827.12 CDS30515.1 - 6e-28 97.5 0.2 1.1e-27 96.7 0.2 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nsp1_C PF05064.13 CDS30516.1 - 2.8e-26 91.6 0.8 7.1e-26 90.3 0.8 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region WD40 PF00400.32 CDS30516.1 - 7.6e-22 77.2 8.7 0.0027 18.5 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS30516.1 - 7.9e-07 29.3 0.0 0.03 14.6 0.0 3.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 CDS30516.1 - 0.45 9.8 3.6 0.63 9.4 3.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 CDS30516.1 - 3.9 7.8 6.6 2 8.7 2.7 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Abhydrolase_1 PF00561.20 CDS30518.1 - 2.7e-19 69.8 0.3 3.4e-18 66.2 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CDS30518.1 - 3.6e-17 61.7 0.0 2.6e-16 58.9 0.1 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CDS30518.1 - 3e-07 30.0 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDS30518.1 - 0.00013 22.7 0.5 0.00021 22.0 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CHORD PF04968.12 CDS30520.1 - 6e-48 161.4 25.2 8.5e-24 84.1 7.5 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 CDS30520.1 - 5.1e-09 37.0 0.0 9.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 CS domain vATP-synt_E PF01991.18 CDS30521.1 - 6.3e-61 205.3 1.8 7.3e-61 205.1 1.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SWIRM-assoc_2 PF16496.5 CDS30522.2 - 2.7e-56 191.2 0.3 5.1e-55 187.0 0.0 2.8 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 CDS30522.2 - 2.3e-32 111.2 1.4 2.7e-32 110.9 0.1 1.9 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CDS30522.2 - 3.9e-29 100.4 14.2 9.9e-29 99.1 14.2 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM-assoc_3 PF16498.5 CDS30522.2 - 1e-18 67.3 0.7 1e-18 67.3 0.7 2.4 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal Myb_DNA-binding PF00249.31 CDS30522.2 - 8e-12 45.2 0.0 1.9e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS30522.2 - 2e-07 31.1 0.0 6.2e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HMA PF00403.26 CDS30523.1 - 0.018 15.5 0.7 0.031 14.7 0.7 1.4 1 0 0 1 1 1 0 Heavy-metal-associated domain RF-1 PF00472.20 CDS30524.1 - 9.9e-18 64.2 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain YoeB_toxin PF06769.14 CDS30524.1 - 0.0041 17.1 1.0 0.95 9.5 0.3 2.2 1 1 1 2 2 2 2 YoeB-like toxin of bacterial type II toxin-antitoxin system UPF0203 PF05254.12 CDS30525.1 - 4.6e-13 49.2 1.3 5.8e-13 48.9 1.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 CDS30525.1 - 0.05 13.6 1.6 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CDS30525.1 - 0.081 12.7 4.2 4.3 7.1 0.3 2.6 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 CDS30525.1 - 0.2 11.7 3.4 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CDS30525.1 - 0.3 11.3 5.2 0.87 9.8 0.3 2.5 2 1 0 2 2 2 0 CHCH domain Far-17a_AIG1 PF04750.14 CDS30528.1 - 2.3e-05 23.8 5.4 3.1e-05 23.4 5.4 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Zip PF02535.22 CDS30528.1 - 0.0023 17.2 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4834 PF16118.5 CDS30528.1 - 0.0048 17.8 1.1 0.0071 17.3 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) tRNA_anti-like PF12869.7 CDS30528.1 - 0.0061 16.2 0.3 0.0095 15.6 0.3 1.3 1 0 0 1 1 1 1 tRNA_anti-like Connexin PF00029.19 CDS30528.1 - 0.017 14.9 1.3 0.017 14.9 1.3 1.5 2 0 0 2 2 2 0 Connexin MMM1 PF10296.9 CDS30528.1 - 0.023 13.7 1.0 0.03 13.4 1.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 G0-G1_switch_2 PF15103.6 CDS30528.1 - 0.024 15.0 0.3 0.037 14.5 0.3 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2681 PF10883.8 CDS30528.1 - 0.026 14.9 1.8 0.047 14.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 CDS30528.1 - 0.026 15.4 0.1 0.055 14.4 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 CDS30528.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 FAM176 family OATP PF03137.20 CDS30528.1 - 0.031 12.6 0.1 0.035 12.4 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LapA_dom PF06305.11 CDS30528.1 - 0.035 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ECSCR PF15820.5 CDS30528.1 - 0.054 13.3 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Peptidase_S49_N PF08496.10 CDS30528.1 - 0.059 13.4 1.2 0.083 13.0 1.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2615 PF11027.8 CDS30528.1 - 0.061 13.5 1.2 0.094 12.9 0.1 1.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2615) Ctr PF04145.15 CDS30528.1 - 0.077 13.6 1.2 0.39 11.3 0.3 2.0 2 0 0 2 2 2 0 Ctr copper transporter family OAD_gamma PF04277.13 CDS30528.1 - 0.11 13.1 4.7 0.29 11.7 4.7 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UPF0542 PF15086.6 CDS30528.1 - 0.42 10.6 3.2 0.98 9.4 3.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 Tmemb_9 PF05434.11 CDS30528.1 - 1.4 8.8 5.8 0.53 10.2 0.2 2.0 1 1 1 2 2 2 0 TMEM9 Dpy-30 PF05186.13 CDS30529.1 - 6.1e-07 29.0 0.4 2.9e-05 23.7 0.3 2.2 2 0 0 2 2 2 2 Dpy-30 motif DLIC PF05783.11 CDS30530.2 - 4.9e-59 200.4 0.1 2.6e-32 112.3 0.0 2.6 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 CDS30530.2 - 0.00038 20.4 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CDS30530.2 - 0.0019 17.8 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS30530.2 - 0.0036 17.4 0.3 0.13 12.4 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Arf PF00025.21 CDS30530.2 - 0.041 13.3 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 CDS30530.2 - 0.086 12.6 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CDS30530.2 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CDS30530.2 - 0.18 12.1 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CDS30530.2 - 0.33 11.5 0.0 0.33 11.5 0.0 3.1 2 1 0 2 2 2 0 ABC transporter Wtap PF17098.5 CDS30531.1 - 6.4e-46 156.1 8.7 3.8e-45 153.6 8.7 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family Spc7 PF08317.11 CDS30531.1 - 0.0087 15.0 14.3 0.012 14.5 2.7 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF2009 PF09418.10 CDS30531.1 - 0.36 9.9 6.8 0.1 11.7 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) Death PF00531.22 CDS30531.1 - 0.56 10.4 6.6 7.4 6.8 2.9 2.6 2 0 0 2 2 2 0 Death domain PCRF PF03462.18 CDS30531.1 - 1.2 8.9 11.7 3.9 7.3 3.1 2.1 2 0 0 2 2 2 0 PCRF domain DUF812 PF05667.11 CDS30531.1 - 1.3 7.8 14.1 1.7 7.4 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DHR10 PF18595.1 CDS30531.1 - 5.5 7.1 21.8 0.45 10.6 7.0 3.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 CDS30531.1 - 7.8 6.4 11.3 17 5.3 2.9 3.1 3 0 0 3 3 3 0 Prefoldin subunit ER_lumen_recept PF00810.18 CDS30532.1 - 9.2e-57 192.0 13.5 1.6e-56 191.2 13.5 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CDS30532.1 - 0.0037 17.0 4.0 0.2 11.5 0.1 3.5 2 1 0 2 2 2 2 PQ loop repeat zf-RanBP PF00641.18 CDS30533.1 - 2.2e-11 42.9 18.7 5.1e-06 25.7 3.3 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CDS30533.1 - 0.17 11.9 6.5 0.44 10.6 6.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon BUD22 PF09073.10 CDS30533.1 - 0.57 9.5 27.6 0.7 9.2 27.6 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 CDS30533.1 - 1.1 8.8 12.4 1.4 8.4 12.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 CDS30533.1 - 1.7 7.1 14.6 1.9 7.0 14.6 1.0 1 0 0 1 1 1 0 Macoilin family MCLC PF05934.11 CDS30533.1 - 2.1 7.0 4.7 2.7 6.6 4.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Chorion_2 PF03964.15 CDS30533.1 - 2.2 9.2 11.9 1.7 9.5 7.4 2.3 2 0 0 2 2 2 0 Chorion family 2 RecR PF02132.15 CDS30533.1 - 5.6 6.6 8.9 2.4 7.8 1.5 2.4 2 0 0 2 2 2 0 RecR protein TMIE PF16038.5 CDS30534.1 - 0.012 15.5 1.6 0.012 15.5 1.6 2.4 2 1 0 2 2 2 0 TMIE protein WBP-1 PF11669.8 CDS30534.1 - 0.57 10.9 7.0 0.45 11.2 0.4 3.3 3 0 0 3 3 3 0 WW domain-binding protein 1 Shisa PF13908.6 CDS30534.1 - 1.3 9.2 5.7 0.31 11.3 0.8 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 CDS30534.1 - 2.8 7.9 12.5 0.59 10.0 0.1 3.6 3 1 1 4 4 4 0 TMEM154 protein family ECSCR PF15820.5 CDS30534.1 - 4.2 7.3 9.5 0.99 9.3 0.1 3.2 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator DUF2207 PF09972.9 CDS30534.1 - 4.3 6.0 15.2 1.2 7.8 1.6 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Y_phosphatase PF00102.27 CDS30535.2 - 9.8e-14 51.5 0.0 1.1e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CDS30535.2 - 5.1e-06 26.3 0.0 6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ank_5 PF13857.6 CDS30536.1 - 5.6e-21 74.3 4.8 8.9e-09 35.5 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS30536.1 - 1.7e-20 73.4 3.9 1.2e-08 35.4 0.0 3.3 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30536.1 - 9.1e-17 61.2 4.1 8.4e-07 29.4 0.2 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PDZ_6 PF17820.1 CDS30536.1 - 3.7e-13 49.1 0.0 8.5e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank PF00023.30 CDS30536.1 - 1.9e-12 47.0 7.4 0.0063 16.9 0.2 5.2 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CDS30536.1 - 3.1e-10 39.4 7.0 0.0038 17.6 0.1 6.2 7 0 0 7 7 7 3 Ankyrin repeat PDZ PF00595.24 CDS30536.1 - 3.7e-10 40.0 0.0 9.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS30536.1 - 0.0001 22.5 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Sec63 PF02889.16 CDS30537.1 - 2.3e-16 59.8 0.4 4.2e-09 35.9 0.2 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 CDS30537.1 - 4.1e-12 46.1 0.2 8.4e-12 45.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF973 PF06157.11 CDS30538.1 - 0.17 10.9 3.6 0.22 10.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4064 PF13273.6 CDS30538.1 - 0.22 11.8 3.7 0.37 11.1 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Phage_holin_4_1 PF05105.12 CDS30538.1 - 1.2 9.3 9.5 1.6 8.9 5.4 2.0 1 1 1 2 2 2 0 Bacteriophage holin family Saf_2TM PF18303.1 CDS30538.1 - 3.1 7.4 5.2 7.2 6.2 0.3 2.0 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF3040 PF11239.8 CDS30538.1 - 4.4 7.6 7.2 5.3 7.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF4870 PF09685.10 CDS30539.1 - 0.0037 17.3 0.1 0.005 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) DUF3611 PF12263.8 CDS30539.1 - 0.0081 16.1 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Tetraspanin PF00335.20 CDS30539.1 - 0.012 15.4 3.4 0.015 15.0 3.4 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4064 PF13273.6 CDS30539.1 - 0.051 13.9 0.4 0.092 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3185 PF11381.8 CDS30539.1 - 0.065 13.3 1.2 4.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Peptidase_U4 PF03419.13 CDS30539.1 - 0.12 11.6 0.2 0.15 11.3 0.2 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PDR_CDR PF06422.12 CDS30539.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.0 1 1 1 2 2 2 0 CDR ABC transporter DUF202 PF02656.15 CDS30539.1 - 0.79 10.2 3.5 6.1 7.4 0.1 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Mo25 PF08569.11 CDS30540.1 - 1.3e-85 287.7 1.5 1.6e-85 287.4 1.5 1.0 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 CDS30540.1 - 0.00029 20.2 1.0 0.14 11.4 0.2 2.2 2 0 0 2 2 2 2 V-ATPase subunit H NBD_C PF17042.5 CDS30540.1 - 0.042 14.3 0.2 0.072 13.6 0.2 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain HEAT_2 PF13646.6 CDS30540.1 - 0.11 12.9 0.2 4.9 7.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats ScsC_N PF18312.1 CDS30540.1 - 1 9.2 3.7 0.82 9.5 0.8 2.3 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain Tetraspanin PF00335.20 CDS30541.2 - 2 8.1 11.8 11 5.7 0.2 2.2 2 0 0 2 2 2 0 Tetraspanin family Fer4_4 PF12800.7 CDS30541.2 - 2.4 8.9 6.6 0.5 11.0 0.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Phage_holin_3_6 PF07332.11 CDS30541.2 - 7.5 6.6 12.3 0.37 10.8 5.2 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Choline_transpo PF04515.12 CDS30542.1 - 7.2e-75 252.2 20.1 8.1e-75 252.0 20.1 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF2244 PF10003.9 CDS30542.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.5 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) NUDIX PF00293.28 CDS30543.1 - 1.3e-13 51.2 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 CDS30543.1 - 0.059 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase DUF3841 PF12952.7 CDS30545.2 - 0.079 12.8 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) SRP40_C PF05022.12 CDS30547.2 - 1.5e-12 48.2 0.4 3.1e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 SRP40, C-terminal domain IMUP PF15761.5 CDS30547.2 - 0.4 11.4 9.9 0.055 14.2 5.3 2.0 3 0 0 3 3 3 0 Immortalisation up-regulated protein Ashwin PF15323.6 CDS30547.2 - 6.4 6.7 9.5 2.5 8.1 0.5 2.3 1 1 1 2 2 2 0 Developmental protein PLDc_3 PF13918.6 CDS30548.1 - 8.8e-30 103.7 0.0 1.4e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 CDS30548.1 - 1.1e-25 90.1 0.0 2.6e-12 46.8 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDS30548.1 - 3.6e-12 45.9 2.5 1.9e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PDCD9 PF07147.12 CDS30549.1 - 2.8e-13 49.9 0.0 9.1e-07 28.4 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) 2-Hacid_dh_C PF02826.19 CDS30550.1 - 2.4e-45 154.1 0.0 4.9e-45 153.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDS30550.1 - 6.4e-25 87.4 0.0 7.4e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 CDS30550.1 - 0.069 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family JmjN PF02375.17 CDS30551.2 - 6.4e-16 58.0 0.7 1.3e-15 57.0 0.7 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 CDS30551.2 - 2.3e-15 57.0 1.1 4e-15 56.3 1.1 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TIP49 PF06068.13 CDS30552.1 - 6.4e-161 535.4 2.6 1e-160 534.8 2.6 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDS30552.1 - 3e-25 88.1 1.0 7.9e-25 86.8 1.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDS30552.1 - 4.4e-11 43.3 1.3 8.9e-08 32.6 0.1 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDS30552.1 - 2.3e-07 30.9 0.1 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDS30552.1 - 5.3e-07 29.5 0.6 0.00038 20.2 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS30552.1 - 1.1e-05 25.9 0.1 3.8e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CDS30552.1 - 3.2e-05 23.4 0.8 0.00052 19.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CDS30552.1 - 7.5e-05 23.1 2.4 0.0019 18.6 1.7 2.7 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CDS30552.1 - 8.1e-05 22.9 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CDS30552.1 - 0.00025 20.7 0.2 0.00051 19.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CDS30552.1 - 0.00055 19.3 0.1 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 CDS30552.1 - 0.0033 17.2 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CDS30552.1 - 0.0076 15.8 0.1 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDS30552.1 - 0.0096 16.1 0.2 0.026 14.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CDS30552.1 - 0.0097 15.4 1.4 0.52 9.7 0.3 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 CDS30552.1 - 0.0099 16.1 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDS30552.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CDS30552.1 - 0.013 15.3 0.8 0.16 11.6 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDS30552.1 - 0.013 16.0 0.1 0.058 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CDS30552.1 - 0.028 14.1 0.2 0.056 13.2 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CDS30552.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CDS30552.1 - 0.043 13.8 0.2 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CDS30552.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CDS30552.1 - 0.073 13.1 3.0 0.084 12.9 0.2 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CDS30552.1 - 0.079 12.2 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CDS30552.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.25 CDS30553.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30553.1 - 0.003 16.9 0.0 0.0049 16.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS30554.1 - 3.5e-11 43.0 0.0 4.1e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30554.1 - 2e-07 30.6 0.0 2.4e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.20 CDS30555.1 - 7.8e-23 80.9 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDS30555.1 - 2e-15 57.7 0.0 1.7e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDS30555.1 - 0.005 16.9 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDS30555.1 - 0.017 14.9 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase 7TM_GPCR_Srw PF10324.9 CDS30557.1 - 2.8e-08 33.4 6.3 3.9e-05 23.1 0.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS30557.1 - 2.6e-07 30.3 0.6 5.1e-07 29.3 0.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C2H2 PF00096.26 CDS30559.2 - 4.2e-06 26.9 10.6 0.0024 18.3 0.1 4.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS30559.2 - 0.89 10.1 16.5 0.27 11.8 2.6 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_2 PF13465.6 CDS30562.1 - 4.4e-05 23.7 5.8 0.0046 17.3 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30562.1 - 0.036 14.5 1.5 0.036 14.5 1.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type FBD PF08387.10 CDS30566.2 - 0.026 14.4 1.3 0.029 14.3 0.4 1.5 2 0 0 2 2 2 0 FBD SH3_1 PF00018.28 CDS30568.2 - 4.1e-13 48.7 0.6 9.7e-13 47.5 0.6 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS30568.2 - 2.8e-10 39.7 0.2 7.8e-10 38.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDS30568.2 - 3.7e-09 36.3 0.2 7e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 CDS30568.2 - 4.9e-08 33.4 0.3 2.8e-07 31.0 0.3 2.0 1 1 0 1 1 1 1 RhoGEF domain RhoGEF67_u2 PF16614.5 CDS30568.2 - 0.098 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 CDC48_N PF02359.18 CDS30568.2 - 0.11 12.6 0.1 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain UPF0183 PF03676.14 CDS30570.1 - 3.8e-129 431.4 0.0 4.3e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) SmpA_OmlA PF04355.13 CDS30570.1 - 0.066 13.0 0.1 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 SmpA / OmlA family DUF3187 PF11383.8 CDS30571.1 - 0.098 11.8 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) HCO3_cotransp PF00955.21 CDS30573.2 - 2.9e-66 224.3 4.2 4.1e-66 223.9 4.2 1.1 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.22 CDS30573.2 - 1.8e-06 27.9 0.7 1.5e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.13 CDS30573.2 - 4.8e-06 26.6 1.1 3.3e-05 23.8 1.1 2.0 1 1 0 1 1 1 1 Band 3 cytoplasmic domain MIG-14_Wnt-bd PF06664.12 CDS30574.2 - 4.2e-26 91.8 17.4 5.9e-25 88.1 10.9 2.6 3 0 0 3 3 3 2 Wnt-binding factor required for Wnt secretion CtaG_Cox11 PF04442.14 CDS30575.2 - 1.4e-61 206.9 0.1 1.8e-61 206.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Diphthamide_syn PF01866.17 CDS30576.2 - 3e-99 332.3 0.2 3.9e-69 233.4 0.1 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein Insulin PF00049.18 CDS30578.1 - 0.0024 18.8 8.5 0.013 16.5 8.5 2.1 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Insulin PF00049.18 CDS30579.2 - 0.00019 22.4 8.2 0.00052 21.0 8.2 1.8 1 1 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.14 CDS30579.2 - 0.62 10.1 8.3 3.5 7.7 3.3 2.6 3 0 0 3 3 3 0 Nematode insulin-related peptide beta type Dopey_N PF04118.14 CDS30580.2 - 9.4e-70 235.1 0.0 4.2e-69 233.0 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal DUF2451 PF10474.9 CDS30580.2 - 8.1e-64 215.6 0.0 2e-63 214.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CDS30580.2 - 1.1e-52 179.1 14.0 2.3e-52 178.1 13.1 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Vps53_N PF04100.12 CDS30580.2 - 3.6e-05 22.9 2.2 0.00017 20.7 1.1 2.5 3 0 0 3 3 3 1 Vps53-like, N-terminal Sec8_exocyst PF04048.14 CDS30580.2 - 0.38 10.6 5.5 0.58 10.0 2.3 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GST_C_3 PF14497.6 CDS30581.1 - 1.3e-18 67.0 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS30581.1 - 7.2e-12 45.4 0.0 1.7e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS30581.1 - 3.9e-08 33.5 0.0 7.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS30581.1 - 1.1e-06 28.5 0.0 3e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDS30581.1 - 3.7e-05 23.4 0.3 0.0001 22.0 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDS30581.1 - 0.0017 18.7 0.0 0.0032 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDS30581.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ribonuc_2-5A PF06479.12 CDS30582.1 - 0.0091 16.2 0.1 0.066 13.4 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A NodS PF05401.11 CDS30582.1 - 0.11 12.1 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Adap_comp_sub PF00928.21 CDS30583.1 - 2.7e-89 299.0 0.0 4e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDS30583.1 - 3.9e-09 36.6 3.5 7e-09 35.8 3.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain eIF_4EBP PF05456.11 CDS30584.1 - 9.9e-38 128.6 0.3 1.1e-37 128.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Protocadherin PF08374.11 CDS30585.1 - 0.13 12.3 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Protocadherin Myticin-prepro PF10690.9 CDS30585.1 - 0.22 11.8 1.5 0.37 11.1 1.5 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Hormone_3 PF00159.18 CDS30586.1 - 0.00062 19.8 0.2 0.0011 19.0 0.2 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide Androgen_recep PF02166.16 CDS30588.1 - 0.25 10.2 3.2 0.32 9.8 3.2 1.1 1 0 0 1 1 1 0 Androgen receptor CAP_N PF01213.19 CDS30588.1 - 0.26 10.8 1.6 0.32 10.4 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 7tm_1 PF00001.21 CDS30589.1 - 1.3e-07 31.3 4.3 2.1e-06 27.3 0.2 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF2593 PF10767.9 CDS30589.1 - 0.24 11.4 3.6 0.27 11.3 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2593) DapB_N PF01113.20 CDS30593.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4774 PF15999.5 CDS30594.1 - 0.17 11.7 3.5 0.27 11.1 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) dUTPase PF00692.19 CDS30594.1 - 0.17 11.5 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 dUTPase ZapB PF06005.12 CDS30595.1 - 0.0045 17.4 3.2 2.6 8.5 0.7 2.8 2 1 2 4 4 4 4 Cell division protein ZapB bZIP_1 PF00170.21 CDS30595.1 - 0.0065 16.5 1.8 0.099 12.8 0.2 2.4 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 CDS30595.1 - 0.028 14.2 1.4 0.92 9.3 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator TolA_bind_tri PF16331.5 CDS30595.1 - 0.16 12.1 2.0 20 5.4 0.0 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation Actin PF00022.19 CDS30597.1 - 2.1e-124 415.3 0.0 7.3e-124 413.5 0.0 1.7 1 1 0 1 1 1 1 Actin DUF2369 PF10179.9 CDS30598.1 - 0.05 14.0 2.0 0.12 12.8 0.1 2.7 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) EF-hand_1 PF00036.32 CDS30599.1 - 1.2e-33 112.2 16.5 1.2e-08 33.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS30599.1 - 9.2e-28 96.5 4.6 7e-14 52.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS30599.1 - 1.6e-25 86.8 9.6 4.5e-07 29.3 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS30599.1 - 3.6e-25 87.6 7.2 1.5e-10 40.8 0.2 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDS30599.1 - 4.8e-23 79.6 9.4 9.1e-07 28.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 CDS30599.1 - 9e-10 38.4 2.4 0.0014 18.5 0.2 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS30599.1 - 3.3e-08 33.8 0.0 0.0058 16.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS30599.1 - 9.8e-07 29.0 0.1 0.0025 18.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 CDS30599.1 - 0.00013 21.9 0.1 0.0017 18.4 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CDS30599.1 - 0.0002 21.5 4.4 0.17 12.1 0.2 3.2 1 1 2 3 3 3 3 Dockerin type I domain UPF0154 PF03672.13 CDS30599.1 - 0.0018 18.3 0.3 0.015 15.3 0.0 2.6 4 0 0 4 4 4 1 Uncharacterised protein family (UPF0154) VCBS PF13517.6 CDS30599.1 - 0.024 15.2 4.9 1.9 9.1 0.0 3.3 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3349 PF11829.8 CDS30599.1 - 0.04 14.7 0.0 1.1 10.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 CDS30599.1 - 0.069 13.1 0.6 5.5 6.9 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein EF-hand_11 PF08976.11 CDS30599.1 - 0.088 13.7 0.0 0.42 11.5 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain RES PF08808.11 CDS30600.1 - 0.0017 18.3 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 RES domain DEAD PF00270.29 CDS30601.1 - 2.6e-38 131.5 0.0 5.3e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CDS30601.1 - 6.1e-21 74.4 1.9 9.1e-21 73.9 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CDS30601.1 - 3.6e-20 72.4 0.0 1e-17 64.5 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS30601.1 - 1.1e-05 25.5 0.0 0.00068 19.7 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 CDS30602.2 - 4.4e-26 91.8 0.0 6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30602.2 - 2.5e-12 46.6 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS30602.2 - 3.5e-07 29.4 0.5 5e-07 28.9 0.5 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDS30602.2 - 0.057 13.3 0.0 0.3 11.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Parvo_NS1 PF01057.17 CDS30612.1 - 4.9e-05 22.6 0.1 5.4e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS30612.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Papillomavirus helicase ANAPC1 PF12859.7 CDS30613.1 - 5.1e-08 33.6 0.5 4.9e-05 23.9 0.0 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CDS30613.1 - 0.35 11.4 13.9 0.82 10.2 1.4 4.8 5 0 0 5 5 5 0 Proteasome/cyclosome repeat Ets PF00178.22 CDS30614.2 - 2.4e-23 82.4 0.1 4.7e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Ets-domain DAP3 PF10236.9 CDS30615.1 - 1.5e-47 162.3 0.0 2e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 PAP2 PF01569.21 CDS30616.1 - 3.6e-12 46.2 13.5 1.4e-11 44.4 13.5 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 CDS30616.1 - 0.011 15.9 1.7 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF1453 PF07301.11 CDS30616.1 - 0.02 14.9 3.2 0.028 14.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) PAP2_C PF14360.6 CDS30616.1 - 2 9.0 10.5 4 8.0 9.6 2.1 1 1 0 1 1 1 0 PAP2 superfamily C-terminal NCU-G1 PF15065.6 CDS30617.1 - 7.2e-16 58.1 0.0 7.1e-15 54.9 0.0 2.0 1 1 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 MPS2 PF17060.5 CDS30618.1 - 0.015 14.6 3.5 0.023 14.0 3.5 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 FemAB PF02388.16 CDS30618.1 - 0.038 12.9 4.1 0.056 12.3 4.1 1.1 1 0 0 1 1 1 0 FemAB family KLRAQ PF10205.9 CDS30618.1 - 0.082 13.1 10.5 0.16 12.2 10.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF4239 PF14023.6 CDS30618.1 - 0.49 10.1 3.5 1 9.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF724 PF05266.14 CDS30618.1 - 1.4 8.8 10.5 2.6 7.8 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.12 CDS30618.1 - 2 8.8 11.2 2.8 8.4 10.3 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) GAS PF13851.6 CDS30618.1 - 3.6 6.9 19.1 0.36 10.2 11.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CDS30618.1 - 3.8 8.1 10.9 7.6 7.1 10.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C3H1 PF10650.9 CDS30618.1 - 5.1 6.9 7.3 0.14 11.9 0.5 2.0 2 0 0 2 2 2 0 Putative zinc-finger domain TMPIT PF07851.13 CDS30618.1 - 5.2 6.2 8.0 12 5.0 7.6 1.8 2 0 0 2 2 2 0 TMPIT-like protein SNF PF00209.18 CDS30619.1 - 6.9e-37 127.3 42.6 2.7e-21 75.9 22.0 2.1 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family Laps PF10169.9 CDS30619.1 - 8.3e-11 42.6 13.9 3.6e-05 24.3 5.9 2.2 1 1 1 2 2 2 2 Learning-associated protein DUF2423 PF10338.9 CDS30619.1 - 0.0084 16.3 8.8 0.0084 16.3 8.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) MPM1 PF17234.2 CDS30619.1 - 0.31 11.3 2.3 0.53 10.5 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Clat_adaptor_s PF01217.20 CDS30620.1 - 9e-53 178.0 2.2 1.1e-52 177.8 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_14 PF17978.1 CDS30621.1 - 4.9e-20 71.8 3.1 4.9e-20 71.8 3.1 2.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DZR PF12773.7 CDS30621.1 - 6.6e-12 45.3 63.2 2.5e-07 30.6 6.1 6.3 5 1 0 5 5 4 4 Double zinc ribbon CHB_HEX_C_1 PF13290.6 CDS30621.1 - 1.8e-10 40.6 0.1 4.2e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CDS30621.1 - 6e-10 39.1 0.1 1.3e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Fn3 associated Ank_2 PF12796.7 CDS30621.1 - 2.9e-09 37.4 0.1 0.00062 20.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDS30621.1 - 5.2e-09 36.1 0.3 0.00028 21.2 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDS30621.1 - 1.8e-08 34.0 1.0 0.0036 17.7 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 CDS30621.1 - 7.3e-08 32.8 0.1 0.0028 18.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS30621.1 - 3.9e-06 27.0 0.3 9.7e-05 22.6 0.0 3.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) zinc_ribbon_2 PF13240.6 CDS30621.1 - 1.7e-05 24.4 53.2 0.0017 18.0 1.9 8.3 7 0 0 7 7 7 4 zinc-ribbon domain ubiquitin PF00240.23 CDS30621.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zinc_ribbon_15 PF17032.5 CDS30621.1 - 0.11 13.3 51.3 0.82 10.5 10.1 6.6 5 1 1 6 6 6 0 zinc-ribbon family zf-ribbon_3 PF13248.6 CDS30621.1 - 0.63 9.5 56.3 0.62 9.6 1.5 9.2 9 0 0 9 9 9 0 zinc-ribbon domain Carb_anhydrase PF00194.21 CDS30622.1 - 6.9e-64 215.8 0.0 8.2e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VHP PF02209.19 CDS30624.1 - 4e-15 55.6 2.7 1.4e-13 50.6 2.4 2.7 2 0 0 2 2 2 1 Villin headpiece domain Gelsolin PF00626.22 CDS30624.1 - 6.8e-14 51.5 0.0 0.005 16.7 0.0 4.7 4 0 0 4 4 4 3 Gelsolin repeat Arf PF00025.21 CDS30625.1 - 8e-59 198.0 0.0 9.1e-59 197.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS30625.1 - 1.6e-11 44.5 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS30625.1 - 5.5e-10 39.1 0.0 7.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CDS30625.1 - 2.6e-08 33.5 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDS30625.1 - 6.7e-08 32.1 0.2 2.1e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CDS30625.1 - 7.8e-08 32.4 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS30625.1 - 0.00064 19.3 0.3 0.024 14.2 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 CDS30625.1 - 0.0027 17.3 0.1 0.19 11.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 CDS30625.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NOG1 PF06858.14 CDS30625.1 - 0.078 12.8 0.2 0.33 10.8 0.2 1.9 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Y_phosphatase PF00102.27 CDS30626.1 - 2.2e-68 230.3 0.0 3.5e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 CDS30626.1 - 2.4e-47 158.9 0.4 1.7e-23 82.5 0.0 2.8 3 0 0 3 3 3 2 SH2 domain DSPc PF00782.20 CDS30626.1 - 0.0033 17.3 1.3 0.004 17.0 0.2 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS30626.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Endonuclease_NS PF01223.23 CDS30627.1 - 9.3e-49 166.3 0.0 1.1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease LRR_6 PF13516.6 CDS30628.1 - 4e-14 51.4 10.8 0.084 13.0 0.1 8.2 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 CDS30628.1 - 3.6e-06 27.2 7.3 0.063 13.7 0.4 5.2 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS30628.1 - 0.0016 18.2 8.0 6.6 6.6 0.9 5.4 3 2 2 5 5 5 1 Leucine rich repeat LRR_1 PF00560.33 CDS30628.1 - 0.11 13.1 6.6 1.5e+02 3.5 1.4 6.2 4 2 0 4 4 4 0 Leucine Rich Repeat SDA1 PF05285.12 CDS30628.1 - 0.6 9.5 8.0 1 8.7 8.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDS30628.1 - 1.5 7.0 13.1 0.68 8.1 10.9 1.5 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.11 CDS30628.1 - 3.1 6.2 9.9 11 4.4 10.2 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 CDS30628.1 - 3.3 7.0 9.7 2.6 7.3 7.2 1.9 2 0 0 2 2 2 0 BUD22 DUF2457 PF10446.9 CDS30628.1 - 8.8 5.3 14.5 16 4.5 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDP-OH_P_transf PF01066.21 CDS30631.1 - 1.1e-12 48.5 0.8 1.1e-12 48.5 0.8 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HEAT_2 PF13646.6 CDS30632.1 - 1.2e-05 25.6 0.0 0.0007 19.9 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Peptidase_M1 PF01433.20 CDS30632.1 - 0.0047 16.5 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDS30632.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain DUF4902 PF16245.5 CDS30634.1 - 0.14 12.1 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) SH3_2 PF07653.17 CDS30635.1 - 9.5e-07 28.4 0.0 2.7e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS30635.1 - 5.3e-06 25.9 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS30635.1 - 0.011 15.6 0.4 0.045 13.6 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain SH3_3 PF08239.11 CDS30635.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain ubiquitin PF00240.23 CDS30636.1 - 6.8e-10 38.6 0.2 9e-10 38.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS30636.1 - 0.0074 16.1 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-CHY PF05495.12 CDS30637.1 - 1.4e-11 44.7 9.1 1.4e-11 44.7 9.1 4.3 4 2 0 4 4 4 1 CHY zinc finger zf-CCCH_4 PF18044.1 CDS30637.1 - 2.1e-08 33.7 33.3 0.0023 17.7 1.7 3.9 3 0 0 3 3 3 3 CCCH-type zinc finger zf-CCCH PF00642.24 CDS30637.1 - 2.6e-07 30.4 36.8 0.00046 20.0 2.1 4.1 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS30637.1 - 4.6e-06 26.5 40.8 0.0098 15.9 2.3 4.2 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 CDS30637.1 - 0.00034 21.3 25.6 0.041 14.6 1.9 3.8 2 1 2 4 4 4 3 Torus domain RWD PF05773.22 CDS30637.1 - 0.012 15.9 0.6 0.047 14.0 0.1 2.1 2 0 0 2 2 2 0 RWD domain muHD PF10291.9 CDS30638.1 - 1.7e-13 50.6 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CDS30638.1 - 2e-06 28.0 0.7 3.3e-05 24.1 0.3 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Ead_Ea22 PF13935.6 CDS30638.1 - 0.015 15.9 1.7 0.035 14.8 1.7 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein STAT_alpha PF01017.20 CDS30638.1 - 0.11 12.4 4.7 0.24 11.3 4.7 1.6 1 0 0 1 1 1 0 STAT protein, all-alpha domain Streptin-Immun PF11083.8 CDS30638.1 - 0.19 12.1 1.0 0.55 10.7 1.0 1.8 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein APG6_N PF17675.1 CDS30638.1 - 9 6.8 9.4 2.1 8.9 5.9 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 CDS30639.1 - 7.6e-71 238.6 0.0 4e-50 170.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30639.1 - 6.4e-19 68.2 0.0 2.4e-12 46.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDS30639.1 - 1.1e-07 32.1 0.0 0.0083 16.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CDS30639.1 - 0.00037 20.2 0.2 0.69 9.5 0.0 2.7 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDS30639.1 - 0.00057 19.3 0.0 0.0071 15.7 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CDS30639.1 - 0.003 16.4 0.0 0.012 14.4 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase RVT_1 PF00078.27 CDS30640.1 - 1e-16 61.1 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FucT_N PF18025.1 CDS30642.1 - 0.023 15.2 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain Nuc_deoxyri_tr2 PF15891.5 CDS30645.1 - 1.9e-17 63.6 0.1 1.2e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Nop53 PF07767.11 CDS30645.1 - 0.011 15.1 0.2 0.021 14.2 0.2 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SPX PF03105.19 CDS30645.1 - 0.058 13.3 1.3 3.9 7.3 0.0 2.1 1 1 1 2 2 2 0 SPX domain Dynein_light PF01221.18 CDS30646.1 - 1.7e-15 57.1 0.0 2.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 CDS30646.1 - 5.6e-07 29.9 0.5 1.2e-06 28.9 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS30646.1 - 0.00027 20.6 0.6 0.0037 17.1 0.2 2.4 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CDS30646.1 - 0.00035 19.9 0.2 0.00099 18.5 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CDS30646.1 - 0.00051 19.4 0.2 0.0089 15.5 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CDS30646.1 - 0.084 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair PPP4R2 PF09184.11 CDS30647.1 - 7.6e-24 84.8 43.3 7.6e-20 71.7 43.3 3.9 1 1 0 1 1 1 1 PPP4R2 LIM PF00412.22 CDS30648.1 - 8.9e-12 45.1 8.8 1.4e-11 44.4 8.8 1.4 1 0 0 1 1 1 1 LIM domain DUF2318 PF10080.9 CDS30648.1 - 0.69 10.1 6.9 0.85 9.8 1.0 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-C2H2 PF00096.26 CDS30649.1 - 1.3e-30 104.2 48.4 7.9e-05 22.9 1.1 8.4 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30649.1 - 2.5e-28 96.3 47.3 0.0077 17.0 0.1 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS30649.1 - 4.6e-24 83.7 40.6 0.00047 20.5 0.3 9.0 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS30649.1 - 4.2e-12 46.0 40.6 0.0011 19.2 0.3 8.3 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS30649.1 - 8.1e-12 45.1 34.4 0.033 14.6 0.1 8.5 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDS30649.1 - 1.1e-09 38.4 30.9 0.00049 20.3 3.0 4.7 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CDS30649.1 - 2.6e-07 30.5 38.9 0.0066 16.4 0.0 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS30649.1 - 0.00015 21.4 38.6 0.0096 15.7 0.2 7.5 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 CDS30649.1 - 0.013 16.2 9.6 0.013 16.2 9.6 7.7 3 2 2 6 6 5 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 CDS30649.1 - 0.086 13.0 21.7 1.5 9.0 0.5 5.2 3 2 0 4 4 4 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 CDS30649.1 - 0.11 12.8 22.8 0.65 10.3 0.3 4.3 2 1 1 4 4 4 0 C2H2-type zinc ribbon zf_Hakai PF18408.1 CDS30649.1 - 0.13 12.0 13.4 14 5.5 0.4 4.9 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain FYVE PF01363.21 CDS30649.1 - 4 7.6 36.6 0.44 10.7 7.5 5.2 2 2 2 4 4 4 0 FYVE zinc finger zinc_ribbon_9 PF14369.6 CDS30649.1 - 4.6 7.6 18.1 12 6.3 0.1 5.7 6 1 0 6 6 5 0 zinc-ribbon zf-C2H2_9 PF16293.5 CDS30649.1 - 8 6.4 8.0 43 4.0 0.2 3.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Arf PF00025.21 CDS30650.1 - 4.3e-46 156.6 0.0 5e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDS30650.1 - 7.6e-06 25.3 0.2 0.0055 15.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDS30650.1 - 9.3e-05 21.9 0.0 0.0039 16.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDS30650.1 - 0.00016 21.9 0.1 0.00047 20.4 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDS30650.1 - 0.00039 19.9 0.0 0.00067 19.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CDS30650.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.3 1 1 0 1 1 1 0 Ras family MMR_HSR1 PF01926.23 CDS30650.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase HECT PF00632.25 CDS30651.1 - 2.7e-54 184.7 0.0 2.7e-53 181.5 0.0 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.6 CDS30651.1 - 1.7e-06 28.5 0.0 0.0016 19.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS30651.1 - 2.6e-06 27.9 0.2 9.9e-06 26.1 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS30651.1 - 0.036 14.6 0.2 13 6.8 0.0 3.9 2 1 1 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 CDS30651.1 - 0.17 12.3 0.2 14 6.1 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) ENTH PF01417.20 CDS30652.1 - 1.6e-38 131.6 0.0 2.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDS30652.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 ANTH domain YAF2_RYBP PF17219.3 CDS30653.1 - 1.6e-14 53.2 0.0 3.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Yaf2/RYBP C-terminal binding motif zf-RanBP PF00641.18 CDS30653.1 - 9.4e-09 34.4 3.3 1.9e-08 33.5 3.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Zn_ribbon_17 PF17120.5 CDS30654.1 - 0.0012 18.5 11.6 0.0029 17.2 11.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 CDS30654.1 - 0.047 13.9 6.6 0.033 14.4 3.9 2.1 1 1 1 2 2 2 0 Zinc-ribbon like family HMG_box PF00505.19 CDS30655.1 - 0.00016 22.0 3.5 0.00016 22.0 3.5 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box Peptidase_C14 PF00656.22 CDS30656.1 - 6e-39 134.5 0.0 9e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CARD PF00619.21 CDS30656.1 - 1.1e-14 54.2 0.2 3e-14 52.8 0.2 1.8 2 0 0 2 2 2 1 Caspase recruitment domain CARD_2 PF16739.5 CDS30656.1 - 1.4e-06 28.2 0.3 4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Caspase recruitment domain GCFC PF07842.12 CDS30657.1 - 1.1e-59 202.3 16.3 1.9e-59 201.6 16.3 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 CDS30657.1 - 6.6e-22 77.8 4.5 1.5e-21 76.7 4.5 1.5 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal G-patch PF01585.23 CDS30657.1 - 1.1e-14 54.0 4.6 2.2e-14 53.0 4.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS30657.1 - 0.00013 22.0 0.3 0.00035 20.6 0.3 1.7 1 0 0 1 1 1 1 G-patch domain GAS PF13851.6 CDS30657.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DNA_gyraseA_C PF03989.13 CDS30657.1 - 0.24 10.9 0.7 3.4 7.2 0.2 2.4 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller SET PF00856.28 CDS30658.1 - 1.7e-09 38.3 0.0 3.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-P11 PF03854.14 CDS30658.1 - 0.0041 16.8 6.5 0.0041 16.8 6.5 2.4 2 0 0 2 2 2 1 P-11 zinc finger TPR_2 PF07719.17 CDS30658.1 - 0.0078 16.3 1.2 1.7 8.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30658.1 - 0.06 13.2 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS30658.1 - 0.065 13.5 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cadherin PF00028.17 CDS30659.1 - 1.6e-58 195.1 0.0 8.6e-13 48.6 0.0 9.1 7 3 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CDS30659.1 - 4.3e-07 29.7 0.0 0.1 12.5 0.0 5.1 5 0 0 5 5 5 2 Cadherin-like TMEM154 PF15102.6 CDS30659.1 - 0.0087 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_4 PF17803.1 CDS30659.1 - 0.0093 16.6 11.0 0.056 14.1 0.2 4.6 4 0 0 4 4 4 1 Bacterial cadherin-like domain DUF3377 PF11857.8 CDS30659.1 - 0.017 15.1 0.2 0.046 13.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cadherin_3 PF16184.5 CDS30659.1 - 0.036 14.1 3.3 9.2 6.3 0.0 5.0 5 0 0 5 5 5 0 Cadherin-like fn3 PF00041.21 CDS30659.1 - 0.071 13.5 0.0 29 5.1 0.0 2.9 2 0 0 2 2 2 0 Fibronectin type III domain TBPIP PF07106.13 CDS30661.1 - 0.026 14.5 0.9 19 5.3 0.1 3.9 2 1 3 5 5 5 0 TBPIP/Hop2 winged helix domain GerD PF17898.1 CDS30661.1 - 0.069 13.1 0.4 0.41 10.6 0.1 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF1828 PF08861.10 CDS30661.1 - 0.073 13.4 0.6 0.53 10.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1828 DUF445 PF04286.12 CDS30661.1 - 0.17 11.7 2.0 0.18 11.6 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF445) G-patch PF01585.23 CDS30662.2 - 8.8e-11 41.5 3.0 2.3e-10 40.2 3.0 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDS30662.2 - 8.2e-08 32.0 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 CDS30662.2 - 0.4 10.8 2.4 1.4 9.0 0.3 2.8 3 0 0 3 3 3 0 G-patch domain LRR_4 PF12799.7 CDS30663.1 - 1.3e-13 50.9 16.1 3.8e-07 30.3 2.3 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) PX PF00787.24 CDS30663.1 - 1.3e-13 50.9 0.3 3.3e-13 49.6 0.3 1.6 1 0 0 1 1 1 1 PX domain LRR_9 PF14580.6 CDS30663.1 - 2.7e-12 46.5 1.4 5e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CDS30663.1 - 7e-12 44.9 14.5 1e-06 28.4 6.5 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CDS30663.1 - 0.37 11.5 9.6 4.2 8.3 0.5 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CDS30663.1 - 9.9 6.5 10.9 0.99 9.6 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DHHC PF01529.20 CDS30664.1 - 9.9e-35 119.6 13.4 1.5e-34 119.0 13.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase PP1_inhibitor PF05361.12 CDS30665.1 - 1.5e-05 25.0 2.3 1.8e-05 24.8 2.3 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Med30 PF11315.8 CDS30665.1 - 0.0059 16.8 1.0 0.0068 16.6 1.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 SNARE_assoc PF09335.11 CDS30666.1 - 8.3e-07 29.5 0.5 8.3e-07 29.5 0.5 2.3 3 1 0 3 3 3 1 SNARE associated Golgi protein Fungus-induced PF10917.8 CDS30666.1 - 0.13 12.6 1.6 0.17 12.3 0.2 1.9 2 0 0 2 2 2 0 Fungus-induced protein Plasmod_dom_1 PF09715.10 CDS30666.1 - 0.3 11.2 1.9 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Integrase_H2C2 PF17921.1 CDS30667.1 - 1.3e-09 38.0 0.3 2e-09 37.4 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain CBFD_NFYB_HMF PF00808.23 CDS30669.1 - 1.6e-06 28.3 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS30669.1 - 0.028 14.8 3.9 0.042 14.2 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SH3_1 PF00018.28 CDS30670.1 - 5.9e-05 22.6 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS30670.1 - 0.00091 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BLOC1_2 PF10046.9 CDS30670.1 - 0.0067 16.7 0.2 0.0067 16.7 0.2 2.8 4 0 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SH3_9 PF14604.6 CDS30670.1 - 0.096 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain Casc1 PF12366.8 CDS30670.1 - 0.13 11.7 6.7 0.07 12.6 4.3 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 OmpH PF03938.14 CDS30670.1 - 0.88 9.9 12.5 0.088 13.2 6.3 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HCMV_UL139 PF12507.8 CDS30670.1 - 1.1 9.6 6.3 2.5 8.5 0.0 3.7 2 2 2 4 4 4 0 Human Cytomegalovirus UL139 protein MIP PF00230.20 CDS30671.2 - 7.1e-31 107.7 5.7 9.3e-31 107.3 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 CDS30672.2 - 2.8e-19 69.7 5.2 4.9e-19 68.9 5.2 1.4 1 1 0 1 1 1 1 Major intrinsic protein TPR_1 PF00515.28 CDS30673.1 - 6.3e-05 22.6 5.5 0.027 14.3 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30673.1 - 0.00084 19.3 5.0 0.021 14.9 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS30673.1 - 0.001 19.6 0.8 0.0027 18.2 0.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDS30673.1 - 0.0011 19.1 2.6 0.0012 19.1 0.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS30673.1 - 0.0033 17.6 0.2 0.012 15.8 0.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDS30673.1 - 0.044 13.5 1.5 0.15 11.7 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 CDS30673.1 - 0.05 13.9 0.1 0.2 12.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30673.1 - 0.068 13.8 0.2 0.63 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS30673.1 - 0.08 13.6 0.5 0.71 10.6 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30673.1 - 0.15 12.3 2.1 1.5 9.3 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SAM_2 PF07647.17 CDS30674.1 - 2.8e-14 53.0 1.7 1.1e-08 35.0 0.1 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 CDS30674.1 - 1.2e-11 45.3 0.0 3.3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 TIR domain SAM_1 PF00536.30 CDS30674.1 - 8.8e-10 38.9 0.7 0.00047 20.5 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) KIND PF16474.5 CDS30674.1 - 0.065 13.1 0.5 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain SAM_3 PF18016.1 CDS30674.1 - 0.1 12.4 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HMMR_N PF15905.5 CDS30674.1 - 0.28 10.6 4.3 0.56 9.6 4.3 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Ig_3 PF13927.6 CDS30675.1 - 0.0033 18.0 0.4 0.11 13.0 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CDS30675.1 - 0.0037 17.3 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain NFACT-R_1 PF05670.13 CDS30676.1 - 5.3e-31 107.5 0.0 1.6e-30 105.9 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CDS30676.1 - 1.8e-26 92.1 0.1 1.8e-26 92.1 0.1 2.9 3 1 0 3 3 3 1 NFACT protein C-terminal domain TPK_catalytic PF04263.16 CDS30676.1 - 0.041 13.9 0.8 8.7 6.4 0.3 2.9 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Dpy-30 PF05186.13 CDS30677.1 - 1.3e-17 63.2 0.1 1.6e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif MRG PF05712.13 CDS30678.1 - 6e-42 143.2 0.9 1e-41 142.5 0.9 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CDS30678.1 - 8.3e-13 48.0 2.0 1.7e-12 47.0 2.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF927 PF06048.11 CDS30678.1 - 0.021 14.4 0.2 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Chromo PF00385.24 CDS30678.1 - 3.4 7.6 7.3 2.7 8.0 3.9 2.3 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain CUT PF02376.15 CDS30679.1 - 8.5e-32 109.2 1.1 1.5e-31 108.4 0.3 1.9 2 0 0 2 2 2 1 CUT domain Homeodomain PF00046.29 CDS30679.1 - 2e-10 40.3 0.4 5.3e-10 39.0 0.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS30679.1 - 0.00018 21.4 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain START PF01852.19 CDS30680.1 - 1.9e-30 105.9 0.0 2.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 CDS30680.1 - 0.0017 18.4 0.1 0.0041 17.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) SH3_9 PF14604.6 CDS30681.1 - 1.3e-14 53.8 0.4 2.4e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS30681.1 - 2.2e-14 52.8 0.1 4.5e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 CDS30681.1 - 1.7e-10 41.0 0.2 1.7e-10 41.0 0.2 3.1 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CDS30681.1 - 2.7e-09 36.6 0.0 6.2e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF4337 PF14235.6 CDS30681.1 - 1.8 8.6 8.8 0.29 11.2 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) BRE1 PF08647.11 CDS30681.1 - 2.4 8.3 11.0 5.8 7.1 2.4 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2524 PF10732.9 CDS30681.1 - 8.1 6.8 8.6 3.2 8.1 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) T3SSipB PF16535.5 CDS30681.1 - 8.5 6.8 8.9 1.4 9.4 2.9 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB HhH-GPD PF00730.25 CDS30683.1 - 5.2e-19 68.7 0.0 8.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDS30683.1 - 3.7e-09 36.0 0.0 1.5e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CDS30683.1 - 0.044 14.4 0.1 0.25 12.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain OTU PF02338.19 CDS30684.1 - 4.1e-17 62.9 1.1 1e-16 61.6 0.0 2.2 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDS30684.1 - 1.8e-05 24.4 0.3 0.086 12.3 0.1 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain BicD PF09730.9 CDS30685.1 - 1.1e-110 371.2 97.7 2.1e-109 367.0 84.7 3.6 1 1 1 2 2 2 1 Microtubule-associated protein Bicaudal-D EKAL PF17986.1 CDS30685.1 - 0.047 13.7 0.5 0.27 11.3 0.1 2.5 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain ApoO PF09769.9 CDS30685.1 - 0.05 13.6 0.4 0.05 13.6 0.4 4.6 3 2 1 5 5 5 0 Apolipoprotein O PE PF00934.20 CDS30685.1 - 0.076 13.3 2.1 7.2 7.0 0.3 3.2 2 0 0 2 2 2 0 PE family DUF1796 PF08795.10 CDS30685.1 - 0.65 9.9 10.5 1.1 9.2 0.4 4.1 2 1 1 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) PI_PP_I PF18363.1 CDS30685.1 - 3 8.1 9.8 1.6 8.9 2.4 3.5 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain zf-C2H2 PF00096.26 CDS30686.1 - 5.9e-05 23.3 14.2 4.6 7.9 0.4 6.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30686.1 - 0.00013 22.5 16.9 5.9 8.0 0.4 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS30686.1 - 0.95 9.8 13.1 2.4 8.6 0.1 4.9 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS30686.1 - 4.3 7.9 10.8 36 4.9 0.0 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type PDZ PF00595.24 CDS30687.1 - 7.9e-40 135.1 0.0 6.6e-13 48.8 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDS30687.1 - 5.2e-28 96.7 0.2 3.6e-09 36.3 0.0 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDS30687.1 - 6.3e-15 55.3 0.0 0.00012 22.3 0.0 3.4 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 CDS30687.1 - 2.6e-05 24.1 0.0 5.4 7.0 0.0 3.6 3 0 0 3 3 3 3 Tricorn protease PDZ domain PDZ_4 PF17816.1 CDS30687.1 - 0.12 12.7 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Chromo PF00385.24 CDS30692.1 - 3.3e-16 58.9 0.2 7.4e-16 57.8 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ank_4 PF13637.6 CDS30692.1 - 6.2e-09 36.2 0.0 2e-06 28.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS30692.1 - 4.6e-06 27.1 0.0 1.4e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS30692.1 - 2.9e-05 24.1 0.0 0.15 12.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDS30692.1 - 0.00043 20.6 0.0 1.9 9.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CDS30692.1 - 0.078 13.3 0.2 5.4 7.5 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Glutaredoxin PF00462.24 CDS30693.1 - 1.9e-17 63.2 0.0 7.9e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CDS30693.1 - 6.4e-16 58.2 0.3 1.6e-15 57.0 0.1 1.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 CDS30693.1 - 2.2e-06 27.6 0.3 0.00011 22.2 0.3 3.0 2 2 1 3 3 3 1 Thioredoxin domain Thioredoxin_6 PF13848.6 CDS30693.1 - 8.8e-06 25.7 0.1 0.0007 19.5 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDS30693.1 - 2.1e-05 24.0 0.1 2.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CDS30693.1 - 0.0012 19.3 0.1 0.0074 16.7 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDS30693.1 - 0.0024 18.1 0.4 0.55 10.6 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like DIM1 PF02966.16 CDS30693.1 - 0.0057 16.4 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 CDS30693.1 - 0.016 15.2 0.3 0.035 14.0 0.2 1.6 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 CDS30693.1 - 0.017 15.3 0.2 0.062 13.5 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CDS30693.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TrbC_Ftype PF09673.10 CDS30693.1 - 0.07 13.2 0.1 5.5 7.1 0.0 2.5 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Pkinase PF00069.25 CDS30694.1 - 1.8e-27 96.4 0.0 1.8e-25 89.8 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30694.1 - 3.1e-24 85.6 0.0 3.8e-20 72.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase TGF_beta_GS PF08515.12 CDS30694.1 - 8.4e-08 31.6 0.0 2.4e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 CDS30694.1 - 0.0049 15.7 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDS30694.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 CDS30695.1 - 2.7e-31 107.2 0.0 1.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDS30695.1 - 4.7e-06 26.6 0.2 0.00036 20.5 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 CDS30695.1 - 0.0019 18.0 0.0 0.0052 16.6 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDS30695.1 - 0.13 11.9 0.0 13 5.4 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_2 PF08587.11 CDS30697.1 - 0.089 12.9 0.0 15 5.8 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Bromodomain PF00439.25 CDS30698.1 - 2.3e-13 50.0 0.0 5.9e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ANAPC10 PF03256.16 CDS30699.1 - 2.2e-56 190.4 0.0 2.5e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CDS30699.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain XRCC1_N PF01834.16 CDS30699.1 - 0.023 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 XRCC1 N terminal domain LIM PF00412.22 CDS30700.1 - 3.3e-58 193.8 65.6 3.8e-14 52.7 3.3 5.1 5 0 0 5 5 5 5 LIM domain zf-RanBP PF00641.18 CDS30700.1 - 0.045 13.1 0.6 0.045 13.1 0.6 6.2 8 1 0 8 8 8 0 Zn-finger in Ran binding protein and others CBM_5_12_2 PF14600.6 CDS30700.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Cellulose-binding domain zf-C4pol PF14260.6 CDS30700.1 - 1 9.9 41.2 1.5 9.4 0.2 6.6 3 2 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta TBCC PF07986.12 CDS30701.1 - 3.5e-24 84.8 1.9 1.1e-18 67.0 1.2 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C CAP_C PF08603.11 CDS30701.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Ank_2 PF12796.7 CDS30702.1 - 1.1e-10 42.0 1.2 1.9e-08 34.8 0.0 3.1 2 1 1 3 3 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS30702.1 - 6.2e-08 32.3 0.8 0.18 12.4 0.0 4.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDS30702.1 - 8.8e-08 32.6 1.1 0.0033 18.0 0.1 4.3 3 2 1 4 4 3 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 CDS30702.1 - 2.7e-07 30.8 8.7 0.017 15.4 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS30702.1 - 1.4e-06 27.9 1.0 0.0062 16.5 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30702.1 - 1.4e-06 27.9 0.9 0.54 10.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_5 PF13857.6 CDS30702.1 - 3.5e-06 27.2 0.9 0.0022 18.2 0.0 3.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) TPR_8 PF13181.6 CDS30702.1 - 1.8e-05 24.6 2.2 0.31 11.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank PF00023.30 CDS30702.1 - 9.3e-05 22.7 2.1 1 9.9 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat TPR_10 PF13374.6 CDS30702.1 - 0.00029 20.6 0.1 0.009 15.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30702.1 - 0.00053 19.7 1.0 0.62 10.0 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30702.1 - 0.005 17.5 0.4 0.53 11.0 0.4 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30702.1 - 0.021 15.6 0.3 14 6.8 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Par3_HAL_N_term PF12053.8 CDS30702.1 - 0.028 14.6 0.0 0.095 12.9 0.0 1.9 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins ANAPC3 PF12895.7 CDS30702.1 - 0.041 14.1 3.3 7.4 6.9 0.2 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CDS30702.1 - 0.056 12.8 2.9 1 8.6 0.3 2.8 2 1 1 3 3 3 0 MalT-like TPR region FAST_1 PF06743.15 CDS30702.1 - 0.082 12.9 1.4 28 4.8 0.0 3.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 ANAPC5 PF12862.7 CDS30702.1 - 0.097 12.7 2.2 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 CDS30702.1 - 0.18 12.3 0.5 18 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 CDS30702.1 - 0.72 10.1 22.3 4.9 7.5 0.1 6.6 6 0 0 6 6 6 0 Leucine Rich repeat RPN7 PF10602.9 CDS30702.1 - 0.77 9.4 5.0 3.5 7.3 0.1 3.5 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 CDS30702.1 - 0.79 10.5 2.3 1.1e+02 3.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_1 PF00560.33 CDS30702.1 - 4.9 8.1 19.7 83 4.4 0.0 7.3 6 0 0 6 6 5 0 Leucine Rich Repeat ERM PF00769.19 CDS30703.1 - 0.00015 21.6 13.3 0.0002 21.3 13.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 CDS30703.1 - 0.0088 15.5 11.4 0.011 15.2 11.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Mad3_BUB1_I_2 PF17014.5 CDS30703.1 - 0.057 13.5 2.0 0.063 13.4 0.8 1.7 1 1 1 2 2 2 0 Putative Mad3/BUB1 like region 1 protein APG6_N PF17675.1 CDS30703.1 - 0.088 13.3 17.7 0.47 11.0 16.2 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Nup54 PF13874.6 CDS30703.1 - 0.18 11.9 9.7 0.27 11.3 9.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 CDS30703.1 - 0.33 8.8 8.9 0.38 8.6 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 CDS30703.1 - 0.37 11.0 16.5 0.37 11.0 1.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 betaPIX_CC PF16523.5 CDS30703.1 - 0.39 10.6 10.1 0.55 10.1 5.2 2.6 1 1 1 2 2 2 0 betaPIX coiled coil FlaC_arch PF05377.11 CDS30703.1 - 0.48 10.9 12.4 3.8 8.0 3.9 3.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CDS30703.1 - 1.3 9.4 13.6 5.7 7.4 13.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 CDS30703.1 - 1.3 8.2 8.4 1.9 7.6 8.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Suppressor_APC PF11414.8 CDS30703.1 - 1.8 8.7 8.7 6.3 6.9 2.7 2.4 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF724 PF05266.14 CDS30703.1 - 2.5 7.9 15.5 10 5.9 15.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PI3K_P85_iSH2 PF16454.5 CDS30703.1 - 4.9 6.7 18.9 0.83 9.2 9.8 2.6 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 CDS30703.1 - 6.5 6.8 8.1 7.1 6.7 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Proteasome PF00227.26 CDS30704.1 - 2.1e-48 164.4 0.1 3e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDS30704.1 - 2.7e-11 42.9 0.3 4.6e-11 42.2 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HdeA PF06411.11 CDS30704.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family I-set PF07679.16 CDS30705.1 - 0.01 15.8 0.0 0.029 14.4 0.0 1.8 1 1 0 1 1 1 0 Immunoglobulin I-set domain DUF3512 PF12024.8 CDS30706.2 - 8.6e-14 51.6 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) RdRP_4 PF02123.16 CDS30707.1 - 0.24 10.2 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Ank_2 PF12796.7 CDS30708.1 - 1.9e-36 124.5 4.8 8.7e-17 61.5 0.3 2.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS30708.1 - 1.7e-20 70.9 1.6 6.2e-06 26.2 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CDS30708.1 - 2.5e-20 71.9 3.4 1.5e-07 31.5 0.5 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CDS30708.1 - 1.9e-18 66.3 4.9 4e-07 30.2 0.1 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS30708.1 - 3e-15 56.3 1.4 6.3e-09 36.2 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) BLM_N PF16202.5 CDS30708.1 - 0.098 11.8 2.1 0.15 11.1 2.1 1.2 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein LIM PF00412.22 CDS30709.1 - 5.2e-52 173.9 46.9 5.9e-14 52.0 2.7 4.2 4 0 0 4 4 4 4 LIM domain ADK_lid PF05191.14 CDS30709.1 - 0.59 10.2 10.4 33 4.6 0.1 5.7 5 0 0 5 5 5 0 Adenylate kinase, active site lid SIX1_SD PF16878.5 CDS30710.1 - 5.4e-33 113.8 0.2 5.4e-33 113.8 0.2 2.1 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CDS30710.1 - 6.4e-13 48.3 3.5 1.3e-12 47.3 3.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS30710.1 - 1.1e-11 44.4 1.1 2.2e-11 43.4 1.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDS30710.1 - 0.024 14.1 0.1 0.082 12.4 0.1 1.9 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.6 CDS30710.1 - 0.049 14.1 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 CDS30710.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.13 CDS30710.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TAP_C PF03943.13 CDS30711.1 - 0.011 15.3 0.1 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 TAP C-terminal domain Con-6 PF10346.9 CDS30712.1 - 0.091 12.8 1.3 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Conidiation protein 6 CTC1_2 PF15491.6 CDS30712.1 - 0.098 11.9 0.4 0.14 11.5 0.4 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Band_7 PF01145.25 CDS30714.1 - 5.1e-30 104.8 0.3 6.5e-30 104.4 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDS30714.1 - 0.0014 18.4 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 CDS30714.1 - 0.071 13.5 0.2 0.15 12.5 0.2 1.7 1 0 0 1 1 1 0 Phage protein Gp68 DEAD PF00270.29 CDS30715.1 - 2.8e-20 72.8 0.0 8e-20 71.3 0.0 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS30715.1 - 1.6e-19 70.3 3.6 2.3e-19 69.8 1.6 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Pox_MCEL PF03291.16 CDS30715.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme NAGidase PF07555.13 CDS30716.1 - 5.6e-60 203.1 0.0 2.9e-58 197.5 0.0 2.3 1 1 0 1 1 1 1 beta-N-acetylglucosaminidase SPOR PF05036.13 CDS30716.1 - 0.073 13.5 0.5 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Sporulation related domain GREB1 PF15782.5 CDS30716.1 - 1.8 5.6 7.2 2.6 5.1 7.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CDS30716.1 - 8.2 4.8 11.9 16 3.9 11.9 1.3 1 0 0 1 1 1 0 Macoilin family JmjC PF02373.22 CDS30717.2 - 1.1e-22 80.7 0.3 5e-22 78.5 0.3 2.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase TPR_1 PF00515.28 CDS30717.2 - 6.9e-22 76.3 11.8 2.6e-05 23.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30717.2 - 1.6e-13 49.7 8.3 0.002 18.1 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS30717.2 - 4.7e-12 45.1 11.5 0.021 15.0 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS30717.2 - 3.5e-11 42.7 1.4 0.035 14.5 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDS30717.2 - 5.9e-09 36.1 8.8 0.3 11.4 0.0 5.9 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS30717.2 - 1.9e-08 33.9 1.9 0.022 14.4 0.0 5.1 3 1 3 6 6 5 2 TPR repeat TPR_14 PF13428.6 CDS30717.2 - 1.8e-06 28.3 0.2 0.3 12.0 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS30717.2 - 9.5e-06 26.0 0.6 0.01 16.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS30717.2 - 4.1e-05 24.1 1.4 1.7 9.4 0.0 4.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS30717.2 - 0.00053 19.8 9.5 0.22 11.6 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat MFS_2 PF13347.6 CDS30717.2 - 0.0078 14.8 0.7 0.014 13.9 0.7 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein ANAPC3 PF12895.7 CDS30717.2 - 0.014 15.6 0.0 0.014 15.6 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDS30717.2 - 0.024 15.3 9.2 32 5.5 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 CDS30717.2 - 0.1 12.7 0.2 9.1 6.4 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 CDS30717.2 - 0.16 12.2 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS30717.2 - 0.49 10.3 2.0 27 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 CDS30718.1 - 1.9e-05 25.1 0.0 6.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CDS30718.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CDS30718.1 - 0.042 14.3 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_8 PF01501.20 CDS30719.1 - 1.1e-21 77.6 0.1 2.7e-19 69.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CDS30719.1 - 0.0035 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pox_LP_H2 PF03356.15 CDS30721.1 - 0.05 13.5 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Viral late protein H2 MOZART2 PF12926.7 CDS30722.1 - 1.1e-08 34.5 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zf-C2H2_2 PF12756.7 CDS30723.1 - 0.024 14.9 2.9 0.05 14.0 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.8 CDS30723.1 - 0.052 13.3 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sgf11 PF08209.11 CDS30723.1 - 0.095 12.3 0.3 0.095 12.3 0.3 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.12 CDS30723.1 - 0.17 12.2 5.8 1.3 9.3 0.7 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 CDS30723.1 - 0.18 10.3 0.9 0.26 9.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-BED PF02892.15 CDS30723.1 - 0.36 10.9 3.6 0.83 9.7 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.7 CDS30723.1 - 1.3 9.5 9.0 0.16 12.4 4.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDS30723.1 - 1.7 9.7 10.0 0.65 11.0 0.6 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CDS30724.1 - 2.9e-10 40.1 6.5 0.0044 17.7 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS30724.1 - 2.9e-08 33.9 7.6 0.0071 16.7 0.1 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CDS30724.1 - 3.7e-08 33.4 8.5 0.001 19.4 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.7 CDS30724.1 - 4.6e-08 33.2 12.7 0.00086 19.6 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS30724.1 - 2.3e-06 27.7 16.5 0.034 14.4 0.3 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CDS30724.1 - 0.0035 17.3 10.3 3.6 7.7 0.1 3.4 3 0 0 3 3 3 2 BED zinc finger c-SKI_SMAD_bind PF08782.10 CDS30724.1 - 0.022 15.0 6.4 0.14 12.4 0.6 2.7 3 0 0 3 3 3 0 c-SKI Smad4 binding domain zf-Di19 PF05605.12 CDS30724.1 - 0.05 13.9 0.3 0.05 13.9 0.3 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF678 PF05077.12 CDS30724.1 - 0.28 11.3 4.0 0.18 12.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-C2H2_6 PF13912.6 CDS30724.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.12 CDS30724.1 - 0.89 8.0 7.4 2.3 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_9 PF16293.5 CDS30724.1 - 3.1 7.7 10.6 20 5.2 0.3 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Annexin PF00191.20 CDS30725.1 - 9.3e-54 179.4 1.6 4.9e-18 65.0 0.0 4.8 4 1 0 4 4 4 4 Annexin Mo25 PF08569.11 CDS30725.1 - 0.033 13.6 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Mo25-like Ku PF02735.16 CDS30726.1 - 4.4e-33 114.7 0.0 8.2e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CDS30726.1 - 7.5e-23 81.0 0.0 2.1e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 CDS30726.1 - 2e-11 44.1 0.2 3.9e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CDS30726.1 - 0.0026 18.0 0.1 0.013 15.7 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain Lysozyme_like PF13702.6 CDS30726.1 - 0.13 12.0 0.1 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Lysozyme-like Renin_r PF07850.14 CDS30728.1 - 0.032 14.8 0.0 4.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Renin receptor-like protein DUF2207 PF09972.9 CDS30728.1 - 0.17 10.6 1.4 2.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF948 PF06103.11 CDS30728.1 - 3.7 7.9 5.3 0.67 10.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BAH PF01426.18 CDS30729.1 - 1.2e-17 63.9 1.3 2.2e-17 63.0 1.3 1.5 1 0 0 1 1 1 1 BAH domain ELM2 PF01448.24 CDS30729.1 - 2.3e-11 44.3 0.0 5.4e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain MTA_R1 PF17226.2 CDS30729.1 - 0.0071 16.5 0.7 0.0071 16.5 0.7 2.3 2 0 0 2 2 2 1 MTA R1 domain Myb_DNA-binding PF00249.31 CDS30729.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain MDM1 PF15501.6 CDS30730.1 - 0.45 9.6 28.9 1.3e+03 -1.8 28.9 3.1 1 1 0 1 1 1 0 Nuclear protein MDM1 Ras PF00071.22 CDS30731.1 - 7.2e-29 100.5 0.0 4.1e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDS30731.1 - 1.7e-10 41.2 0.0 4.5e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30731.1 - 3.8e-06 26.4 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS30731.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS30731.1 - 0.0044 16.9 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDS30731.1 - 0.009 16.3 0.0 0.09 13.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDS30731.1 - 0.0099 16.3 0.1 0.035 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CDS30731.1 - 0.024 14.3 0.2 0.057 13.1 0.1 1.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDS30731.1 - 0.031 14.0 0.7 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CDS30731.1 - 0.07 13.6 0.0 0.82 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 CDS30731.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein KcnmB2_inactiv PF09303.10 CDS30731.1 - 0.57 10.0 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 KCNMB2, ball and chain domain NAD_kinase PF01513.21 CDS30732.1 - 1.1e-47 162.7 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CDS30732.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HTH_48 PF17906.1 CDS30733.1 - 7.3e-06 26.0 0.0 9.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Retrotrans_gag PF03732.17 CDS30734.1 - 0.0061 16.8 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein AAA_32 PF13654.6 CDS30734.1 - 0.013 14.3 1.0 0.017 13.9 1.0 1.1 1 0 0 1 1 1 0 AAA domain UDPGP PF01704.18 CDS30736.1 - 6.6e-162 538.9 0.1 7.7e-162 538.6 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SPATA9 PF15824.5 CDS30737.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 La PF05383.17 CDS30738.1 - 6.5e-09 35.7 0.3 1.9e-08 34.2 0.3 1.8 1 0 0 1 1 1 1 La domain La PF05383.17 CDS30739.2 - 9.2e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 La domain IMUP PF15761.5 CDS30740.1 - 0.99 10.1 4.7 1.6 9.5 4.7 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Arfaptin PF06456.13 CDS30741.1 - 4.3e-37 127.9 9.6 7.4e-36 123.9 9.6 2.0 1 1 0 1 1 1 1 Arfaptin-like domain BAR PF03114.18 CDS30741.1 - 1e-06 28.6 6.4 6e-06 26.1 6.4 2.2 1 1 0 1 1 1 1 BAR domain Sigma70_ner PF04546.13 CDS30741.1 - 0.00042 20.3 1.9 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF1493 PF07377.12 CDS30741.1 - 0.009 16.5 0.2 0.97 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1493) EspB_PE PF18625.1 CDS30741.1 - 0.057 13.9 1.8 0.85 10.1 0.4 2.6 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain DegS PF05384.11 CDS30741.1 - 1.6 8.2 8.6 0.5 9.8 0.4 2.4 2 0 0 2 2 2 0 Sensor protein DegS DUF3391 PF11871.8 CDS30741.1 - 1.7 9.2 0.0 1.7 9.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Integrin_alpha2 PF08441.12 CDS30742.1 - 4.1e-07 29.3 0.0 1.4e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 CDS30742.1 - 3.8e-06 26.9 9.0 2.3e-05 24.4 0.8 3.6 3 0 0 3 3 3 1 FG-GAP repeat VCBS PF13517.6 CDS30742.1 - 0.00018 22.0 0.0 0.0011 19.5 0.0 2.5 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LYRIC PF15686.5 CDS30742.1 - 0.046 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family EF-hand_1 PF00036.32 CDS30744.1 - 4.9e-24 82.1 5.9 1.7e-08 33.4 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDS30744.1 - 8.8e-20 70.9 2.6 5.6e-13 49.1 0.1 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS30744.1 - 5e-19 66.5 5.2 2.9e-08 33.0 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CDS30744.1 - 3.1e-14 51.7 7.1 8.3e-07 28.2 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS30744.1 - 2.8e-12 46.3 4.6 8.7e-08 31.9 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDS30744.1 - 2.1e-09 37.6 0.0 4.5e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CDS30744.1 - 0.0004 20.3 0.1 0.003 17.5 0.0 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDS30744.1 - 0.014 15.3 0.0 0.48 10.3 0.0 2.3 1 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 CDS30744.1 - 0.027 14.8 0.1 3.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FGAR-AT_linker PF18072.1 CDS30744.1 - 0.048 14.2 0.0 0.24 12.0 0.0 2.1 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_14 PF17959.1 CDS30744.1 - 0.095 13.1 0.1 1.2 9.5 0.0 2.2 1 1 0 2 2 2 0 EF-hand domain VbhA PF18495.1 CDS30744.1 - 0.13 12.1 0.1 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Antitoxin VbhA SYF2 PF08231.12 CDS30745.2 - 2.2e-46 158.2 6.6 2.2e-46 158.2 6.6 2.0 2 0 0 2 2 2 1 SYF2 splicing factor DUF1912 PF08930.10 CDS30745.2 - 0.02 15.1 0.6 0.057 13.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) DUF3037 PF11236.8 CDS30745.2 - 0.18 12.2 3.3 2.6 8.5 0.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3037) HMG_box_2 PF09011.10 CDS30746.2 - 0.44 11.2 2.5 3.8 8.2 0.1 2.1 2 0 0 2 2 2 0 HMG-box domain MRP-S28 PF10213.9 CDS30747.1 - 9.1e-13 48.7 0.1 2.1e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein MORN PF02493.20 CDS30748.1 - 2.3e-17 61.7 31.3 4.8e-05 23.0 4.2 7.6 7 2 0 7 7 7 4 MORN repeat OmpA PF00691.20 CDS30748.1 - 0.011 16.1 0.0 0.067 13.6 0.0 2.3 1 0 0 1 1 1 0 OmpA family Sec62 PF03839.16 CDS30749.1 - 3.6e-41 141.1 0.0 5.4e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 TPH PF13868.6 CDS30750.2 - 0.24 9.9 70.0 0.02 13.4 18.9 2.7 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain Piwi PF02171.17 CDS30752.2 - 2.3e-83 279.9 0.0 3.5e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CDS30752.2 - 4.5e-13 49.2 0.3 9.6e-13 48.1 0.3 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CDS30752.2 - 4.9e-10 40.2 0.1 1.2e-09 38.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 CDS30752.2 - 0.00079 19.7 0.3 0.003 17.9 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 CDS30752.2 - 0.00084 19.0 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain Ribosomal_L27e PF01777.18 CDS30753.1 - 1.3e-22 79.9 5.3 2e-22 79.3 5.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDS30753.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 KOW motif AXH PF08517.12 CDS30754.2 - 9.4e-08 32.6 0.0 6.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Ataxin-1 and HBP1 module (AXH) CAP PF00188.26 CDS30755.1 - 1.9e-14 54.5 2.0 2.8e-14 54.0 2.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DIRP PF06584.13 CDS30756.1 - 0.0052 17.0 0.2 0.0081 16.3 0.2 1.2 1 0 0 1 1 1 1 DIRP UBN_AB PF14075.6 CDS30756.1 - 0.055 13.2 1.1 0.075 12.7 1.1 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain LPD15 PF18828.1 CDS30756.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 GMC_oxred_C PF05199.13 CDS30756.1 - 0.095 13.2 0.9 0.16 12.5 0.9 1.3 1 0 0 1 1 1 0 GMC oxidoreductase eIF3g PF12353.8 CDS30756.1 - 0.45 10.9 7.4 2.7 8.4 7.2 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Forkhead PF00250.18 CDS30757.1 - 8.3e-36 122.1 0.1 5.7e-35 119.4 0.0 2.0 2 0 0 2 2 2 1 Forkhead domain RRM_1 PF00076.22 CDS30758.1 - 1.3e-10 41.0 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS30758.1 - 0.05 13.7 0.2 0.18 11.9 0.2 2.0 1 1 0 1 1 1 0 RNA recognition motif Ribosomal_L6e PF01159.19 CDS30759.1 - 3.5e-36 124.1 4.7 3.5e-36 124.1 4.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L6e UCMA PF17085.5 CDS30759.1 - 2.8 8.0 7.5 0.096 12.7 0.9 1.9 2 0 0 2 2 2 0 Unique cartilage matrix associated protein AAA_lid_9 PF17871.1 CDS30759.1 - 3.4 7.7 9.2 0.44 10.5 3.9 2.2 2 1 0 2 2 2 0 AAA lid domain MBT PF02820.18 CDS30760.1 - 1.7e-29 101.9 0.0 3.3e-22 78.6 0.0 2.7 2 0 0 2 2 2 2 mbt repeat SAM_1 PF00536.30 CDS30760.1 - 8.7e-05 22.9 0.1 0.00015 22.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C4H2 PF10146.9 CDS30762.1 - 1.6e-69 234.5 27.0 4.1e-68 229.9 27.0 2.0 1 1 0 1 1 1 1 Zinc finger-containing protein DZR PF12773.7 CDS30762.1 - 0.063 13.3 2.4 0.14 12.2 2.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 CDS30762.1 - 0.14 11.8 1.9 0.29 10.8 1.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 CDS30762.1 - 0.15 12.0 4.0 0.25 11.2 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tim17 PF02466.19 CDS30764.1 - 1.1e-14 54.7 1.5 1.5e-14 54.3 1.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Galactosyl_T PF01762.21 CDS30765.1 - 1.5e-18 67.3 0.0 2.7e-18 66.5 0.0 1.4 2 0 0 2 2 2 1 Galactosyltransferase CYSTM PF12734.7 CDS30766.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance AMP-binding PF00501.28 CDS30767.1 - 4.3e-96 322.1 0.1 5.8e-96 321.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Abhydrolase_1 PF00561.20 CDS30768.1 - 5e-07 29.6 0.0 7.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS30768.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDS30768.1 - 9.2e-05 23.1 0.0 0.00013 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 CDS30768.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.18 CDS30768.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 CDS30768.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 CDS30768.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glucosamine_iso PF01182.20 CDS30769.1 - 5.2e-63 212.9 0.0 6e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase eIF2A PF08662.11 CDS30771.2 - 2e-30 106.2 3.7 7.2e-29 101.1 0.4 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDS30771.2 - 1e-05 25.7 0.0 0.029 14.6 0.0 4.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS30771.2 - 0.18 12.7 4.2 12 7.0 0.0 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat BPL_LplA_LipB PF03099.19 CDS30772.2 - 1.2e-05 25.2 0.0 2.2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TORC_N PF12884.7 CDS30773.2 - 0.09 13.6 0.9 0.25 12.1 0.1 2.2 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus FAF PF11250.8 CDS30773.2 - 0.14 12.4 1.0 0.53 10.6 1.0 2.0 1 1 0 1 1 1 0 Fantastic Four meristem regulator Prp18 PF02840.15 CDS30774.1 - 6.8e-57 191.5 0.1 1.8e-56 190.2 0.1 1.7 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 CDS30774.1 - 5.7e-12 45.0 0.3 1e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Epiglycanin_TR PF05647.11 CDS30779.1 - 0.19 11.7 2.7 0.3 11.0 2.7 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like DVL PF08137.12 CDS30779.1 - 0.33 10.9 0.7 0.51 10.2 0.7 1.3 1 0 0 1 1 1 0 DVL family zf-C4 PF00105.18 CDS30783.1 - 6.1e-28 97.1 17.2 9.8e-28 96.4 17.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Ig_3 PF13927.6 CDS30788.1 - 1.2e-11 45.1 0.2 1.3e-05 25.7 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDS30788.1 - 1.3e-11 44.4 0.0 0.0005 20.1 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain RT_RNaseH_2 PF17919.1 CDS30788.1 - 5.4e-11 42.4 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS30788.1 - 3.3e-10 40.2 0.0 7.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ig_2 PF13895.6 CDS30788.1 - 2.1e-07 31.2 0.1 0.00061 20.1 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CDS30788.1 - 3.7e-07 30.2 0.0 0.0057 16.8 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDS30788.1 - 0.00075 19.6 0.2 12 6.1 0.0 3.7 3 1 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS30788.1 - 0.006 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Aminotran_1_2 PF00155.21 CDS30789.1 - 5.4e-31 108.1 0.0 6.9e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDS30789.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Guanylate_cyc PF00211.20 CDS30790.2 - 6.1e-17 61.8 0.0 2.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1980 PF09323.10 CDS30790.2 - 0.13 12.2 1.7 0.46 10.4 1.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) BacA PF02673.18 CDS30790.2 - 6.5 6.4 13.0 1 9.1 0.4 3.2 3 0 0 3 3 3 0 Bacitracin resistance protein BacA PITH PF06201.13 CDS30791.2 - 1.2e-35 122.9 0.2 1.7e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CDS30791.2 - 5.7e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDS30791.2 - 0.00044 20.5 0.4 0.028 14.8 0.1 2.6 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 CDS30791.2 - 0.096 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 CDS30791.2 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 CDS30791.2 - 0.14 11.1 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Phosducin P4Ha_N PF08336.11 CDS30794.2 - 0.0078 16.2 16.4 0.066 13.2 3.7 2.4 1 1 0 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region IL8 PF00048.20 CDS30794.2 - 0.45 10.7 2.0 0.82 9.9 0.2 2.4 2 1 1 3 3 3 0 Small cytokines (intecrine/chemokine), interleukin-8 like zf-C2H2 PF00096.26 CDS30795.2 - 5.8e-14 51.7 40.4 0.0068 16.8 0.2 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30795.2 - 6.2e-13 48.4 34.0 0.0053 17.5 0.2 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CDS30795.2 - 7.2e-13 48.0 13.2 0.0056 16.3 0.1 6.5 6 0 0 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain CpXC PF14353.6 CDS30795.2 - 7.3e-06 26.0 13.5 1.9 8.6 0.0 6.2 4 3 2 7 7 7 2 CpXC protein zf-C2H2_jaz PF12171.8 CDS30795.2 - 3.6e-05 23.9 26.4 0.072 13.4 0.4 6.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CDS30795.2 - 0.00016 21.2 18.6 3.6 7.3 0.1 6.4 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CDS30795.2 - 0.0022 18.0 17.8 1.2 9.3 0.1 6.3 6 0 0 6 6 6 1 Zinc ribbon domain zf-3CxxC PF13695.6 CDS30795.2 - 0.0025 18.2 3.5 1.1e+02 3.3 0.0 5.7 6 0 0 6 6 6 0 Zinc-binding domain Rep_fac-A_C PF08646.10 CDS30795.2 - 0.0036 17.0 2.4 21 4.8 0.0 4.8 5 0 0 5 5 5 0 Replication factor-A C terminal domain zf-AN1 PF01428.16 CDS30795.2 - 0.0041 17.2 15.2 20 5.5 0.1 6.2 6 0 0 6 6 6 0 AN1-like Zinc finger Jas PF16135.5 CDS30795.2 - 0.031 14.5 0.5 1.5 9.0 0.0 3.0 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-C2H2_8 PF15909.5 CDS30795.2 - 0.041 14.2 7.8 11 6.4 0.1 5.2 5 1 1 6 6 5 0 C2H2-type zinc ribbon DUF1033 PF06279.11 CDS30795.2 - 0.058 13.6 0.0 54 4.0 0.0 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1033) zf-C2H2_3rep PF18868.1 CDS30795.2 - 0.1 13.3 15.6 6.5 7.5 3.1 5.2 3 2 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 CDS30795.2 - 0.26 11.9 13.1 14 6.4 0.1 5.2 5 0 0 5 5 4 0 FOXP coiled-coil domain zf_ZIC PF18366.1 CDS30795.2 - 1 9.5 20.3 27 5.0 0.1 6.0 6 0 0 6 6 6 0 Zic proteins zinc finger domain PHD PF00628.29 CDS30795.2 - 1.3 9.0 15.5 28 4.7 0.1 5.6 6 0 0 6 6 6 0 PHD-finger LIM PF00412.22 CDS30795.2 - 2.1 8.7 14.5 32 4.9 0.1 5.6 6 0 0 6 6 6 0 LIM domain HNH_5 PF14279.6 CDS30795.2 - 6.6 6.7 13.6 1.5 8.7 0.2 4.8 6 0 0 6 6 6 0 HNH endonuclease zf-LYAR PF08790.11 CDS30795.2 - 8 6.5 30.2 1.1 9.2 1.9 5.6 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger SYCE1 PF15233.6 CDS30799.1 - 0.015 15.4 1.0 0.015 15.4 1.0 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 ArAE_1_C PF11728.8 CDS30799.1 - 0.05 13.6 5.0 0.24 11.4 5.0 2.0 1 1 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Exonuc_VII_L PF02601.15 CDS30799.1 - 0.27 10.8 1.5 0.48 9.9 1.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DMPK_coil PF08826.10 CDS30799.1 - 0.44 10.7 5.7 0.15 12.2 1.3 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Rootletin PF15035.6 CDS30799.1 - 2.4 8.1 8.7 0.41 10.7 2.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion KH_1 PF00013.29 CDS30800.1 - 1.4e-23 82.5 3.8 2.3e-13 49.7 0.1 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDS30800.1 - 6.4e-09 35.5 7.0 0.00039 20.2 0.2 2.8 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CDS30800.1 - 0.015 15.4 1.8 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 NusA-like KH domain KH_4 PF13083.6 CDS30800.1 - 0.059 13.2 8.0 1 9.3 0.5 3.1 4 0 0 4 4 4 0 KH domain Transposase_1 PF01359.18 CDS30801.1 - 1.6e-08 34.3 0.3 3.4e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Transposase (partial DDE domain) Glyco_hydro_114 PF03537.13 CDS30801.1 - 0.33 10.2 1.2 0.4 9.9 0.1 1.6 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Ig_3 PF13927.6 CDS30804.2 - 1.4e-23 83.3 2.2 4.6e-06 27.1 0.1 6.0 5 1 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 CDS30804.2 - 2.1e-15 56.6 0.0 4.1e-05 23.5 0.0 5.4 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 CDS30804.2 - 2.2e-15 56.6 0.3 1.9e-05 24.7 0.0 6.3 5 3 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 CDS30804.2 - 9.7e-14 51.5 1.7 0.058 13.7 0.2 5.8 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 CDS30804.2 - 7.6e-09 35.7 0.4 3.8 7.7 0.0 6.2 5 1 0 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS30804.2 - 3.6e-07 30.2 2.6 2.6 8.2 0.0 5.7 5 2 0 5 5 5 2 CD80-like C2-set immunoglobulin domain DELLA PF12041.8 CDS30804.2 - 0.17 11.8 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal PAW PF04721.17 CDS30806.1 - 1.4e-60 204.5 0.1 2.2e-60 203.9 0.1 1.3 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Thioredoxin PF00085.20 CDS30806.1 - 9e-17 61.0 0.1 2.3e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 CDS30806.1 - 1.5e-05 25.4 0.1 7.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily AhpC-TSA PF00578.21 CDS30806.1 - 0.0001 22.2 0.1 0.00084 19.2 0.1 2.2 2 0 0 2 2 2 1 AhpC/TSA family PUB PF09409.10 CDS30806.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 PUB domain Thioredoxin_8 PF13905.6 CDS30806.1 - 0.00032 21.0 0.3 0.0023 18.2 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 CDS30806.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Redoxin ACCA PF03255.14 CDS30806.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2635 PF10948.8 CDS30807.1 - 0.14 11.9 1.2 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) CCDC14 PF15254.6 CDS30808.1 - 0.0066 15.2 5.9 0.0082 14.9 5.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 SNF PF00209.18 CDS30811.2 - 1e-107 361.1 15.2 1.2e-107 360.8 15.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF1129 PF06570.11 CDS30811.2 - 2.1 7.8 4.5 5.2 6.5 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1907 PF08925.11 CDS30813.1 - 3.4e-41 141.5 0.0 3.8e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) GLTP PF08718.11 CDS30814.2 - 1.3e-27 96.9 1.8 2.3e-27 96.1 0.2 2.2 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) WD40 PF00400.32 CDS30814.2 - 2.1e-07 31.5 5.8 0.01 16.7 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.11 CDS30814.2 - 3.7e-05 23.5 0.1 0.00031 20.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) TFIIIC_delta PF12657.7 CDS30814.2 - 0.00021 21.3 1.4 2.2 8.2 0.0 4.5 4 0 0 4 4 4 2 Transcription factor IIIC subunit delta N-term PH PF00169.29 CDS30814.2 - 0.074 13.6 0.0 0.32 11.5 0.0 2.2 1 0 0 1 1 1 0 PH domain Tho1_MOS11_C PF18592.1 CDS30815.1 - 3.6e-09 36.3 6.4 3e-06 26.9 2.3 3.4 4 0 0 4 4 4 2 Tho1/MOS11 C-terminal domain SAP PF02037.27 CDS30815.1 - 6.1e-08 32.2 2.8 1.2e-07 31.3 1.0 2.4 2 1 1 3 3 3 1 SAP domain Rho_N PF07498.12 CDS30815.1 - 0.52 10.3 3.7 8 6.5 3.7 2.5 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain Pkinase PF00069.25 CDS30816.1 - 3e-47 161.2 0.0 7e-47 160.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain IF4E PF01652.18 CDS30816.1 - 2.3e-28 99.0 0.1 4.1e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ras PF00071.22 CDS30816.1 - 1e-24 87.0 0.0 2.9e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.17 CDS30816.1 - 2.1e-20 73.1 0.0 4.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Roc PF08477.13 CDS30816.1 - 4.4e-13 49.5 0.0 1.4e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Choline_kinase PF01633.20 CDS30816.1 - 0.031 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CDS30816.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family LTP_2 PF14368.6 CDS30816.1 - 0.45 10.6 5.1 0.21 11.7 0.9 2.7 2 0 0 2 2 2 0 Probable lipid transfer Ras PF00071.22 CDS30817.1 - 1.1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30817.1 - 1.1e-23 83.8 0.0 1.4e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30817.1 - 8.3e-09 35.1 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS30817.1 - 0.025 14.1 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Tti2 PF10521.9 CDS30817.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Tti2 family FBPase PF00316.20 CDS30818.1 - 8.1e-71 237.4 0.1 1.1e-70 237.0 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Peptidase_M14 PF00246.24 CDS30819.1 - 3.2e-11 43.6 0.0 1.1e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CDS30819.1 - 6.8e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Granulin PF00396.18 CDS30820.1 - 9.9e-64 211.4 161.6 3.2e-15 56.2 19.0 8.9 7 2 2 9 9 9 9 Granulin Granulin PF00396.18 CDS30821.1 - 7.5e-51 170.2 142.3 3.5e-13 49.6 23.5 7.0 5 2 2 7 7 7 7 Granulin RasGEF PF00617.19 CDS30822.2 - 1.9e-55 187.8 0.2 1.5e-54 184.8 0.1 2.4 2 0 0 2 2 2 1 RasGEF domain RhoGEF PF00621.20 CDS30822.2 - 1.1e-32 113.8 3.6 1.9e-32 112.9 3.6 1.4 1 0 0 1 1 1 1 RhoGEF domain RasGEF_N PF00618.20 CDS30822.2 - 1.8e-09 37.8 0.0 0.00094 19.4 0.0 2.8 2 0 0 2 2 2 2 RasGEF N-terminal motif PH PF00169.29 CDS30822.2 - 0.00044 20.7 0.7 0.82 10.2 0.1 3.3 3 0 0 3 3 3 2 PH domain IQ PF00612.27 CDS30822.2 - 0.5 10.3 2.9 1.2 9.1 2.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif UQ_con PF00179.26 CDS30823.1 - 2.9e-51 172.8 0.0 3.2e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDS30823.1 - 0.96 9.7 2.8 2.3 8.5 2.8 1.8 1 1 0 1 1 1 0 RWD domain Coatomer_WDAD PF04053.14 CDS30824.2 - 7.7e-146 486.6 0.0 1.7e-145 485.5 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CDS30824.2 - 7.7e-37 124.7 9.8 2.1e-10 41.0 0.1 8.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CDS30824.2 - 0.0001 21.1 1.3 0.51 8.9 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDS30824.2 - 0.00044 20.5 0.4 0.66 10.3 0.0 4.5 2 1 5 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CDS30824.2 - 0.12 12.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term ubiquitin PF00240.23 CDS30825.1 - 1.5e-16 59.9 0.0 2.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDS30825.1 - 5.2e-07 29.5 0.4 1.1e-06 28.5 0.4 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CDS30825.1 - 5.8e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 CDS30825.1 - 0.00066 19.6 22.0 0.027 14.4 3.3 5.2 3 1 2 5 5 5 2 STI1 domain Ubiquitin_5 PF18037.1 CDS30825.1 - 0.0062 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LPD22 PF18834.1 CDS30825.1 - 0.017 15.3 0.6 12 6.2 0.1 3.7 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 Rad60-SLD_2 PF13881.6 CDS30825.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDS30825.1 - 0.05 14.2 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 CDS30825.1 - 0.052 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 HOIP UBA domain pair XPC-binding PF09280.11 CDS30825.1 - 0.11 12.3 25.6 0.066 13.0 3.0 5.4 2 2 3 5 5 5 0 XPC-binding domain BSD PF03909.17 CDS30825.1 - 0.15 12.1 1.7 12 5.9 0.1 3.2 2 1 1 3 3 3 0 BSD domain ScsC_N PF18312.1 CDS30825.1 - 0.17 11.7 4.1 16 5.4 0.1 4.1 3 1 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain ACC_epsilon PF13822.6 CDS30825.1 - 1.8 9.3 4.7 1.2 9.9 0.3 2.7 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Pil1 PF13805.6 CDS30828.1 - 0.016 14.7 6.7 0.019 14.5 6.1 1.4 1 1 0 1 1 1 0 Eisosome component PIL1 PriC PF07445.12 CDS30828.1 - 0.034 14.1 12.6 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Primosomal replication protein priC DUF4164 PF13747.6 CDS30828.1 - 0.13 12.6 10.5 5.7 7.3 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) CCD48 PF15799.5 CDS30828.1 - 0.24 9.7 7.0 0.086 11.1 3.5 1.8 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 48 DUF4854 PF16146.5 CDS30828.1 - 0.54 10.6 4.7 0.24 11.8 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) DUF1539 PF07560.11 CDS30828.1 - 0.88 9.7 8.2 0.58 10.3 3.7 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) CCDC-167 PF15188.6 CDS30828.1 - 0.88 9.9 12.5 51 4.3 8.9 3.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 CDS30828.1 - 1.1 9.7 20.6 3.8 8.0 10.7 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 CDS30828.1 - 1.5 9.2 16.5 0.43 10.9 7.4 3.4 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.10 CDS30828.1 - 2.7 8.5 12.5 3.9 8.0 0.2 3.5 3 1 0 3 3 3 0 DASH complex subunit Dad2 DUF1664 PF07889.12 CDS30828.1 - 2.8 8.0 6.7 5.6 7.0 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 CDS30828.1 - 8.2 4.9 13.6 1.7 7.1 9.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Parvo_NS1 PF01057.17 CDS30830.1 - 6.4e-10 38.6 0.0 8.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS30830.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Parvo_NS1 PF01057.17 CDS30831.1 - 4.4e-19 68.6 2.7 6.3e-14 51.7 0.2 2.8 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS30831.1 - 2.7e-08 33.1 0.3 1.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Papillomavirus helicase Torsin PF06309.11 CDS30831.1 - 0.00014 21.9 0.1 0.38 10.8 0.0 2.5 2 0 0 2 2 2 2 Torsin MMR_HSR1 PF01926.23 CDS30831.1 - 0.0021 18.2 1.1 0.031 14.4 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 CDS30831.1 - 0.0045 17.4 0.1 1.2 9.6 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDS30831.1 - 0.024 14.6 0.2 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CDS30831.1 - 0.055 13.2 0.1 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CDS30831.1 - 0.058 13.8 0.0 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Parvo_NS1 PF01057.17 CDS30832.1 - 9.2e-11 41.3 0.1 3e-10 39.6 0.0 1.7 1 1 1 2 2 2 1 Parvovirus non-structural protein NS1 MPTase-PolyVal PF18818.1 CDS30833.1 - 0.079 13.0 0.5 0.12 12.4 0.5 1.2 1 0 0 1 1 1 0 Metallopeptidase superfamily domain CSD PF00313.22 CDS30836.1 - 6.3e-07 29.2 0.1 8.8e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-H2C2_2 PF13465.6 CDS30837.1 - 1.5e-34 116.8 41.9 1.6e-06 28.2 2.5 7.9 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.26 CDS30837.1 - 1.5e-32 110.2 44.9 1.2e-05 25.5 0.6 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS30837.1 - 5.9e-30 101.3 46.7 7.9e-06 26.3 0.7 7.5 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS30837.1 - 1.2e-16 60.5 37.2 0.00025 21.2 0.1 7.5 6 1 1 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS30837.1 - 8.2e-15 54.4 45.1 0.0037 17.2 0.1 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 CDS30837.1 - 1.2e-11 44.5 35.5 0.002 18.4 0.1 7.5 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDS30837.1 - 1.2e-08 35.1 33.7 0.00018 21.8 5.0 4.6 1 1 6 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 CDS30837.1 - 5.4e-08 32.3 24.7 0.11 12.1 0.1 6.7 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 CDS30837.1 - 2.3e-05 24.7 32.6 1.5 9.3 2.1 7.0 3 1 4 7 7 7 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 CDS30837.1 - 5.3e-05 22.9 32.9 0.026 14.3 0.3 7.0 8 0 0 8 8 7 3 zinc-finger C2H2-type zf-AN1 PF01428.16 CDS30837.1 - 0.00012 22.1 27.1 2 8.6 0.3 7.1 7 0 0 7 7 7 1 AN1-like Zinc finger zf-C2H2_2 PF12756.7 CDS30837.1 - 0.00018 21.8 29.1 0.59 10.5 0.1 5.9 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CDS30837.1 - 0.00028 20.6 53.2 0.0059 16.3 0.0 8.7 8 1 0 8 8 7 4 C2H2-type zinc-finger domain zf_Hakai PF18408.1 CDS30837.1 - 0.00058 19.5 3.4 3.8 7.3 0.1 4.4 3 0 0 3 3 3 1 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 CDS30837.1 - 0.00073 19.6 27.4 0.087 12.9 0.4 5.9 5 2 2 7 7 5 3 Zic proteins zinc finger domain XPA_N PF01286.18 CDS30837.1 - 0.001 19.1 29.1 0.44 10.6 0.2 7.1 7 0 0 7 7 7 1 XPA protein N-terminal Elf1 PF05129.13 CDS30837.1 - 0.0017 18.4 23.6 0.094 12.8 1.9 4.4 1 1 3 4 4 4 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 CDS30837.1 - 0.0017 18.4 24.5 6.6 6.9 0.0 6.2 5 1 1 6 6 6 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 CDS30837.1 - 0.0027 18.0 24.8 0.07 13.4 3.7 4.1 1 1 3 4 4 4 2 C2H2-type zinc ribbon DUF629 PF04780.12 CDS30837.1 - 0.0079 14.8 6.2 0.0079 14.8 6.2 5.7 1 1 5 6 6 6 1 Protein of unknown function (DUF629) zf-C2H2_3rep PF18868.1 CDS30837.1 - 0.0081 16.8 23.3 0.037 14.7 1.0 5.0 1 1 2 4 4 4 2 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CDS30837.1 - 0.013 15.5 20.1 6.1 6.9 0.1 6.3 1 1 6 7 7 7 0 CpXC protein FYVE PF01363.21 CDS30837.1 - 0.016 15.4 27.4 0.64 10.2 7.0 5.2 2 1 2 4 4 3 0 FYVE zinc finger zf-BED PF02892.15 CDS30837.1 - 0.026 14.5 33.8 1.3 9.1 3.1 6.7 4 3 3 7 7 5 0 BED zinc finger GAGA PF09237.11 CDS30837.1 - 0.029 14.2 7.5 0.31 10.9 1.1 3.8 1 1 1 3 3 3 0 GAGA factor TRAF6_Z2 PF18048.1 CDS30837.1 - 0.042 13.9 15.3 2.5 8.3 0.1 5.9 6 1 1 7 7 6 0 TNF receptor-associated factor 6 zinc finger 2 C1_4 PF07975.12 CDS30837.1 - 0.1 12.8 24.4 6.5 7.1 0.0 5.4 2 1 4 6 6 6 0 TFIIH C1-like domain Zn-C2H2_12 PF18112.1 CDS30837.1 - 0.14 12.7 14.4 0.23 11.9 0.1 5.6 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain HypA PF01155.19 CDS30837.1 - 0.16 12.0 17.9 1.8e+04 -6.0 17.9 4.0 1 1 0 1 1 0 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 CDS30837.1 - 0.75 10.1 17.1 37 4.7 0.1 6.5 7 0 0 7 7 7 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 CDS30837.1 - 0.77 9.8 25.5 0.76 9.8 1.4 4.7 3 1 1 4 4 3 0 Transposase zinc-ribbon domain zf-trcl PF13451.6 CDS30837.1 - 0.91 9.5 22.9 11 6.0 0.3 6.0 6 0 0 6 6 6 0 Probable zinc-ribbon domain FBD PF08387.10 CDS30837.1 - 1 9.3 4.6 0.84 9.6 0.2 2.8 3 0 0 3 3 2 0 FBD zf-C2HC_2 PF13913.6 CDS30837.1 - 2.1 8.3 17.4 2 8.4 0.2 5.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Ogr_Delta PF04606.12 CDS30837.1 - 3 7.9 7.2 3.7 7.6 0.4 3.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger LIM PF00412.22 CDS30837.1 - 3.3 8.0 25.9 1.5 9.1 2.2 5.6 4 1 2 6 6 6 0 LIM domain zf-3CxxC PF13695.6 CDS30837.1 - 3.7 8.1 23.0 2.3e+02 2.3 13.0 5.0 1 1 2 3 3 3 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 CDS30837.1 - 4.9 7.2 30.1 4.6 7.2 5.0 6.8 5 2 0 5 5 5 0 zinc-ribbon domain FOXP-CC PF16159.5 CDS30837.1 - 8.1 7.2 22.2 13 6.5 3.4 5.3 2 1 2 5 5 4 0 FOXP coiled-coil domain gag-asp_proteas PF13975.6 CDS30838.2 - 0.072 13.7 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS30838.2 - 0.19 12.4 0.0 0.54 10.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CDS30839.2 - 2.6e-30 105.6 0.0 3.9e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_30C PF17189.4 CDS30840.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Kunitz_BPTI PF00014.23 CDS30844.1 - 1.3e-17 63.7 6.1 1.7e-17 63.4 6.1 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CDS30845.1 - 9e-37 125.1 17.2 3e-19 69.0 4.5 2.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MAAL_N PF05034.13 CDS30845.1 - 0.17 11.5 0.3 6.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus Kunitz_BPTI PF00014.23 CDS30847.1 - 6.5e-18 64.7 5.3 8.2e-18 64.4 5.3 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Neur_chan_LBD PF02931.23 CDS30848.1 - 7.5e-47 159.6 1.6 1.3e-46 158.7 1.6 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS30848.1 - 1.5e-18 67.7 3.6 1.5e-18 67.7 3.6 2.1 2 1 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DUF5524 PF17662.1 CDS30848.1 - 2.3e-05 23.9 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5524) Haspin_kinase PF12330.8 CDS30849.1 - 6.7e-61 206.3 0.0 1.4e-60 205.2 0.0 1.4 1 1 1 2 2 2 1 Haspin like kinase domain Pkinase PF00069.25 CDS30849.1 - 0.042 13.2 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Vsr PF03852.15 CDS30849.1 - 0.048 13.5 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Choline_kinase PF01633.20 CDS30849.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ASXH PF13919.6 CDS30849.1 - 0.13 12.3 0.7 0.41 10.6 0.2 2.1 2 1 0 2 2 2 0 Asx homology domain Thioredoxin PF00085.20 CDS30850.1 - 1.7e-08 34.3 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 CDS30850.1 - 0.00063 19.7 0.0 0.00092 19.1 0.0 1.3 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 CDS30850.1 - 0.0047 16.8 0.1 0.0051 16.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 CDS30850.1 - 0.019 14.7 0.3 0.022 14.6 0.3 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 CDS30850.1 - 0.045 14.2 0.0 0.055 13.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDS30850.1 - 0.071 13.5 0.1 0.18 12.1 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like RRM_1 PF00076.22 CDS30851.1 - 1.4e-07 31.2 0.1 4.4e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CDS30851.1 - 5.3e-06 26.2 5.4 5.3e-06 26.2 5.4 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS30851.1 - 0.012 15.6 3.2 0.025 14.6 3.2 1.6 1 0 0 1 1 1 0 Zinc finger domain Nup35_RRM_2 PF14605.6 CDS30851.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sec15 PF04091.12 CDS30852.1 - 0.084 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Med23 PF11573.8 CDS30853.1 - 2.8e-61 207.6 7.7 2.1e-28 98.6 0.1 4.9 5 0 0 5 5 5 5 Mediator complex subunit 23 Ion_trans PF00520.31 CDS30855.1 - 4.2e-46 157.2 7.9 5.9e-46 156.7 7.9 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDS30855.1 - 3.5e-27 94.6 0.3 8.3e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDS30855.1 - 2.3e-12 46.7 2.9 2.3e-12 46.7 2.9 2.3 2 0 0 2 2 2 1 Ion channel Cytochrom_B_C PF00032.17 CDS30855.1 - 0.46 10.8 2.0 1 9.7 0.6 2.3 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD SSF PF00474.17 CDS30856.1 - 5.5e-50 170.4 23.7 7.8e-50 169.9 23.7 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Frizzled PF01534.17 CDS30857.1 - 2.9e-105 351.9 5.3 4.5e-105 351.3 5.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDS30857.1 - 6.3e-28 97.6 7.1 1.4e-27 96.5 7.1 1.6 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 CDS30857.1 - 0.02 14.0 0.7 0.033 13.3 0.7 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Ost5 PF05251.12 CDS30858.1 - 2.9e-26 91.5 6.2 3.2e-26 91.4 6.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Peptidase_U4 PF03419.13 CDS30858.1 - 0.18 11.1 6.0 0.19 11.0 6.0 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA SNF2_N PF00176.23 CDS30859.1 - 3.5e-74 249.6 1.1 9e-74 248.3 1.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS30859.1 - 5e-22 78.3 0.5 9.4e-21 74.2 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CDS30859.1 - 3.1e-20 72.0 0.2 2e-19 69.4 0.1 2.4 2 0 0 2 2 2 1 Bromodomain ResIII PF04851.15 CDS30859.1 - 8.9e-13 48.6 0.0 3.2e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SnAC PF14619.6 CDS30859.1 - 2.8e-10 40.7 6.7 2.8e-10 40.7 6.7 4.7 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex BRK PF07533.16 CDS30859.1 - 2.8e-08 33.3 0.0 7.4e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 BRK domain HSA PF07529.13 CDS30859.1 - 4.9e-08 33.2 13.2 4.9e-08 33.2 13.2 3.6 4 0 0 4 4 4 1 HSA QLQ PF08880.11 CDS30859.1 - 6.8e-08 32.1 0.1 2.2e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 QLQ DEAD PF00270.29 CDS30859.1 - 3.4e-05 23.7 0.0 9.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase FUSC PF04632.12 CDS30859.1 - 9.7 4.6 8.6 25 3.2 8.6 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_2 PF12796.7 CDS30860.2 - 3.9e-33 113.9 6.5 2.6e-11 43.9 0.4 5.4 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30860.2 - 3.7e-30 103.9 5.1 1.1e-07 32.2 0.1 7.0 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS30860.2 - 2.6e-25 88.1 5.3 9.7e-09 35.3 0.3 6.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS30860.2 - 7e-25 84.4 4.5 0.0041 17.5 0.0 8.7 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 CDS30860.2 - 1.5e-18 66.4 9.6 2.1e-06 27.9 0.1 8.0 7 0 0 7 7 7 4 Ankyrin repeat COR PF16095.5 CDS30860.2 - 0.00031 20.6 0.0 0.00084 19.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain IBN_N PF03810.19 CDS30860.2 - 0.01 15.7 0.6 11 6.0 0.3 3.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain Peptidase_M20 PF01546.28 CDS30862.1 - 2.4e-27 96.0 0.0 3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDS30862.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pro_isomerase PF00160.21 CDS30863.1 - 1.6e-52 178.0 0.0 1.8e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 CDS30863.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) CDK2AP PF09806.9 CDS30866.1 - 1.8e-12 47.8 0.1 1.9e-12 47.8 0.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF4116 PF13475.6 CDS30866.1 - 0.0089 15.7 0.7 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) CDK2AP PF09806.9 CDS30867.1 - 8.8e-17 61.9 0.0 8.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein zf-HC5HC2H_2 PF13832.6 CDS30868.1 - 4.6e-27 94.3 1.9 4.6e-27 94.3 1.9 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDS30868.1 - 2.2e-18 66.3 1.0 2.2e-18 66.3 1.0 2.8 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDS30868.1 - 2.3e-12 46.2 3.8 2.3e-12 46.2 3.8 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CDS30868.1 - 6.9e-11 41.9 7.2 6.9e-11 41.9 7.2 3.3 4 0 0 4 4 4 1 PHD-finger EPL1 PF10513.9 CDS30868.1 - 0.00049 20.5 0.1 0.0017 18.7 0.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.22 CDS30868.1 - 0.0034 17.2 1.1 0.0034 17.2 1.1 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CDS30868.1 - 0.0092 15.9 2.7 0.0092 15.9 2.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 KfrB PF18790.1 CDS30868.1 - 0.039 14.2 0.2 5.8 7.2 0.0 2.6 1 1 1 2 2 2 0 KfrB protein zf-UDP PF14569.6 CDS30868.1 - 1.7 8.9 5.8 4.8 7.4 5.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_2 PF03107.16 CDS30868.1 - 3.8 7.9 20.8 0.16 12.3 2.2 3.7 3 1 0 3 3 3 0 C1 domain Hexokinase_2 PF03727.16 CDS30869.1 - 7.7e-55 185.9 0.0 1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDS30869.1 - 5.3e-17 62.4 0.1 8.3e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Hexokinase NCU-G1 PF15065.6 CDS30870.1 - 2.4e-42 145.2 0.0 1.2e-41 142.9 0.0 1.8 1 1 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 DUF3377 PF11857.8 CDS30870.1 - 0.0068 16.3 0.5 0.018 15.0 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 CDS30870.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family IQ PF00612.27 CDS30871.1 - 2.7e-30 101.3 17.3 2.1e-06 27.0 0.2 5.2 5 0 0 5 5 5 5 IQ calmodulin-binding motif DUF4587 PF15248.6 CDS30871.1 - 4.2 8.2 6.8 0.49 11.2 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4587) Dynein_light PF01221.18 CDS30872.1 - 6.3e-17 61.7 0.0 7e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS30873.2 - 1.8e-18 66.6 0.1 2.3e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4270 PF14092.6 CDS30873.2 - 0.029 13.5 0.0 0.032 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) RL11D PF11088.8 CDS30873.2 - 0.054 13.8 0.1 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF3646 PF12362.8 CDS30873.2 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Dynein_light PF01221.18 CDS30874.1 - 2.4e-21 75.8 0.2 2.9e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 CPW_WPC PF09717.10 CDS30874.1 - 0.045 14.7 1.3 0.91 10.6 0.4 2.3 2 1 1 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) NAD_Gly3P_dh_N PF01210.23 CDS30874.1 - 0.16 12.0 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Dynein_light PF01221.18 CDS30875.1 - 4.1e-20 71.9 0.0 4.8e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS30876.1 - 3.7e-16 59.2 0.0 4.2e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS30877.1 - 8.7e-12 45.2 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 LIM PF00412.22 CDS30878.1 - 2.7e-07 30.7 7.4 6.1e-07 29.6 7.4 1.6 1 0 0 1 1 1 1 LIM domain PARM PF17061.5 CDS30878.1 - 0.069 13.3 5.8 0.11 12.6 5.8 1.3 1 0 0 1 1 1 0 PARM Ras PF00071.22 CDS30879.1 - 7.9e-53 178.4 0.0 9.6e-53 178.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30879.1 - 2.3e-34 118.2 0.0 3.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30879.1 - 2.2e-11 43.5 0.0 2.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS30879.1 - 3.9e-05 23.1 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS30879.1 - 0.00052 20.1 0.0 0.00085 19.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CDS30879.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Hpr_kinase_C PF07475.12 CDS30879.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 CDS30879.1 - 0.17 12.2 0.1 0.26 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TNFR_c6 PF00020.18 CDS30880.1 - 9.8e-26 89.9 51.2 2.8e-10 40.4 9.7 4.7 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region TNFR_16_TM PF18422.1 CDS30880.1 - 1.4e-14 53.7 1.8 1.4e-14 53.7 1.8 2.0 2 0 0 2 2 2 1 Tumor necrosis factor receptor member 16 trans-membrane domain Death PF00531.22 CDS30880.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Death domain Hexokinase_1 PF00349.21 CDS30881.1 - 1.4e-19 70.8 0.0 1.5e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CDS30882.1 - 8.8e-68 228.3 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Hexokinase Baculo_helicase PF04735.12 CDS30882.1 - 0.18 9.3 0.0 0.23 9.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus DNA helicase Mod_r PF07200.13 CDS30883.2 - 1.2e-06 28.7 25.1 0.00062 19.9 0.9 46.5 23 15 25 50 50 50 5 Modifier of rudimentary (Mod(r)) protein Rsa3 PF14615.6 CDS30883.2 - 0.091 12.4 15.0 54 3.5 0.2 8.0 7 0 0 7 7 7 0 Ribosome-assembly protein 3 Ig_3 PF13927.6 CDS30884.1 - 4.2e-26 91.4 0.0 3.9e-11 43.4 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS30884.1 - 2.3e-25 88.4 0.0 7.2e-11 42.0 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS30884.1 - 2.3e-16 59.9 0.1 4.9e-08 33.2 0.0 3.7 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CDS30884.1 - 1.7e-13 50.6 0.0 5.8e-06 26.4 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CDS30884.1 - 2.5e-07 30.8 5.9 0.15 12.2 0.1 4.5 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CDS30884.1 - 0.00046 19.7 0.2 3.7 7.2 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 CDS30884.1 - 0.004 17.2 0.2 20 5.3 0.0 3.3 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain SNAP PF14938.6 CDS30885.1 - 2.2e-05 24.0 2.1 4e-05 23.2 2.1 1.5 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CDS30885.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Tetraspanin PF00335.20 CDS30886.2 - 2.6e-33 115.7 10.6 3e-33 115.5 10.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2650 PF10853.8 CDS30886.2 - 0.00065 19.4 3.3 0.00065 19.4 3.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2650) Anoctamin PF04547.12 CDS30887.1 - 2.7e-121 405.5 9.6 3.7e-121 405.1 9.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CDS30887.1 - 0.0085 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2162 PF09930.9 CDS30887.1 - 0.4 10.0 5.7 0.051 13.0 0.3 2.1 2 1 0 2 2 2 0 Predicted transporter (DUF2162) RVT_1 PF00078.27 CDS30888.1 - 1.8e-12 47.3 0.0 3.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5488 PF17590.2 CDS30888.1 - 0.059 13.1 0.4 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5488) 7tm_1 PF00001.21 CDS30889.1 - 4.7e-16 58.9 20.7 7.3e-16 58.3 20.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS30889.1 - 7.1e-07 29.1 18.5 7.1e-07 29.1 18.5 2.9 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3668 PF12416.8 CDS30890.1 - 5.4e-06 26.4 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Cep120 protein C2 PF00168.30 CDS30890.1 - 9.3e-05 22.7 0.0 0.00035 20.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain RAC_head PF16717.5 CDS30892.1 - 1.9e-15 57.6 0.4 1.9e-15 57.6 0.4 3.3 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 CDS30892.1 - 1.1e-14 54.2 0.8 4e-14 52.5 0.8 2.0 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 CDS30892.1 - 2.1e-11 43.8 0.1 4.3e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS30892.1 - 8.9e-05 22.7 1.4 0.0041 17.3 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Peptidase_C1 PF00112.23 CDS30893.1 - 5.7e-81 271.8 1.3 7.3e-81 271.4 1.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDS30893.1 - 6.4e-09 36.1 0.3 1.1e-08 35.4 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDS30893.1 - 0.00017 20.5 2.2 0.045 12.5 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family F-actin_cap_A PF01267.17 CDS30894.1 - 6.5e-72 242.2 0.0 7.4e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF4641 PF15483.6 CDS30894.1 - 0.016 14.3 0.5 0.021 14.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) PDZ PF00595.24 CDS30895.1 - 6.2e-62 205.9 0.2 2.7e-16 59.7 0.0 4.5 4 0 0 4 4 4 4 PDZ domain LRR_8 PF13855.6 CDS30895.1 - 2.2e-36 123.4 45.0 1.2e-07 31.4 1.0 7.2 3 2 6 9 9 9 9 Leucine rich repeat PDZ_6 PF17820.1 CDS30895.1 - 4.2e-33 113.0 5.8 3e-09 36.6 0.1 5.0 5 0 0 5 5 5 4 PDZ domain LRR_4 PF12799.7 CDS30895.1 - 4.7e-28 96.8 49.8 7e-06 26.3 1.1 8.3 4 3 7 11 11 11 10 Leucine Rich repeats (2 copies) PDZ_2 PF13180.6 CDS30895.1 - 1.3e-20 73.5 1.0 0.00014 22.1 0.0 5.2 5 0 0 5 5 5 4 PDZ domain PDZ_4 PF17816.1 CDS30895.1 - 0.0096 16.3 0.0 6.7 7.2 0.0 3.3 3 0 0 3 3 3 1 PDZ domain FRG1 PF06229.12 CDS30896.1 - 1.8e-63 213.8 0.1 2.4e-63 213.4 0.1 1.1 1 0 0 1 1 1 1 FRG1-like domain DUF1754 PF08555.10 CDS30896.1 - 0.0004 21.1 0.5 0.0004 21.1 0.5 1.8 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) HSP33 PF01430.19 CDS30897.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein Ribosomal_L50 PF10501.9 CDS30898.1 - 6.4e-08 32.7 0.1 8e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S ubiquitin PF00240.23 CDS30899.1 - 1.3e-09 37.6 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS30899.1 - 4.3e-06 26.5 0.1 7.7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 CDS30899.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain Tugs PF17840.1 CDS30899.1 - 0.012 15.8 0.0 0.036 14.2 0.0 1.9 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain RA PF00788.23 CDS30899.1 - 0.047 14.3 0.0 0.28 11.8 0.1 2.0 1 1 1 2 2 2 0 Ras association (RalGDS/AF-6) domain Ubiquitin_5 PF18037.1 CDS30899.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS30899.1 - 0.095 12.8 0.1 5.9 7.0 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain EF-hand_1 PF00036.32 CDS30900.1 - 2.5e-10 39.1 13.2 3.6e-05 23.0 0.1 6.5 7 0 0 7 7 7 2 EF hand EF-hand_8 PF13833.6 CDS30900.1 - 6.6e-10 38.7 10.2 1.6e-05 24.6 2.2 5.4 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS30900.1 - 2.3e-09 36.4 10.7 0.0017 18.1 0.0 6.5 9 0 0 9 9 9 2 EF-hand domain EF-hand_7 PF13499.6 CDS30900.1 - 2.7e-08 34.2 11.1 0.0039 17.6 0.1 5.1 3 3 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS30900.1 - 4.3e-06 26.0 7.1 0.016 14.7 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 CDS30900.1 - 4.7e-05 23.3 0.4 0.56 10.2 0.0 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF499 PF04465.12 CDS30900.1 - 0.014 13.1 0.4 0.019 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) JmjN PF02375.17 CDS30900.1 - 0.98 9.4 4.3 0.41 10.7 0.5 2.3 2 0 0 2 2 2 0 jmjN domain FERM_M PF00373.18 CDS30901.1 - 9.9e-16 58.2 0.2 3.6e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CDS30901.1 - 3.8e-14 52.8 0.0 6.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CDS30901.1 - 3.4e-13 49.3 0.0 5.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain Y_phosphatase PF00102.27 CDS30902.1 - 4.5e-65 219.5 0.3 8.2e-65 218.6 0.3 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 CDS30902.1 - 5.5e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Y_phosphatase3 PF13350.6 CDS30902.1 - 0.004 17.2 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDS30902.1 - 0.04 14.0 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 CDS30902.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Oxidored_q6 PF01058.22 CDS30903.1 - 1e-21 77.1 0.0 1.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit EF-hand_5 PF13202.6 CDS30904.1 - 3.1e-05 23.3 0.0 7.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDS30904.1 - 0.00025 20.8 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDS30904.1 - 0.0004 20.8 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS30904.1 - 0.00073 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDS30904.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair NADHdh PF00146.21 CDS30904.1 - 0.091 12.1 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase NPR2 PF06218.11 CDS30905.1 - 2.4e-28 99.1 0.1 9e-13 47.8 0.1 4.1 4 0 0 4 4 4 4 Nitrogen permease regulator 2 His_Phos_1 PF00300.22 CDS30906.1 - 7.3e-14 51.9 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PhoLip_ATPase_N PF16209.5 CDS30907.1 - 9.8e-20 70.0 1.9 9.8e-20 70.0 1.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDS30907.1 - 1.6e-07 31.1 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDS30907.1 - 3.2e-07 30.3 0.0 9.6e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) CAP PF00188.26 CDS30908.1 - 9.3e-15 55.6 0.0 1.2e-14 55.2 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 CDS30910.1 - 4.1e-18 65.7 0.1 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDS30910.1 - 4.8e-08 32.9 0.0 1.6e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF1474 PF07342.11 CDS30910.1 - 0.0048 17.4 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1474) DUF3232 PF11554.8 CDS30910.1 - 0.15 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Utp14 PF04615.13 CDS30911.1 - 2.7e-83 280.9 53.0 5.4e-44 151.0 9.8 2.1 1 1 1 2 2 2 2 Utp14 protein DUF2385 PF09539.10 CDS30911.1 - 0.19 12.2 2.7 0.27 11.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Noggin PF05806.12 CDS30911.1 - 7.3 6.4 7.7 6.2 6.7 5.0 2.2 1 1 0 1 1 1 0 Noggin Ax_dynein_light PF10211.9 CDS30912.2 - 3e-32 112.1 11.9 3.5e-32 111.8 11.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Tup_N PF08581.10 CDS30912.2 - 0.013 15.8 4.3 0.013 15.8 4.3 2.0 1 1 1 2 2 2 0 Tup N-terminal TPR_MLP1_2 PF07926.12 CDS30912.2 - 0.032 14.3 13.3 0.056 13.5 13.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 CDS30912.2 - 0.044 14.3 6.6 0.093 13.2 6.6 1.5 1 0 0 1 1 1 0 Spectrin repeat RNase_T PF00929.24 CDS30912.2 - 0.047 14.2 2.4 0.084 13.4 2.4 1.3 1 0 0 1 1 1 0 Exonuclease LPP PF04728.13 CDS30912.2 - 0.048 14.0 2.3 0.1 13.0 2.3 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF16 PF01519.16 CDS30912.2 - 0.1 13.1 7.3 0.2 12.1 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 SOGA PF11365.8 CDS30912.2 - 0.16 13.1 0.2 0.16 13.1 0.2 2.3 1 1 1 2 2 2 0 Protein SOGA DUF5320 PF17253.2 CDS30912.2 - 0.29 12.2 0.8 0.47 11.5 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) rve PF00665.26 CDS30914.1 - 2.4e-13 50.3 0.0 3.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Kringle PF00051.18 CDS30915.1 - 0.0031 17.8 0.0 0.015 15.6 0.0 2.2 1 1 0 1 1 1 1 Kringle domain Clc-like PF07062.12 CDS30917.1 - 0.0072 15.8 3.1 0.0089 15.5 3.1 1.1 1 0 0 1 1 1 1 Clc-like SUR7 PF06687.12 CDS30917.1 - 0.057 13.0 5.5 0.076 12.6 5.5 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3671 PF12420.8 CDS30917.1 - 0.18 11.9 3.2 0.27 11.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function Y_phosphatase PF00102.27 CDS30918.1 - 4.4e-71 239.2 0.0 7.1e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.20 CDS30918.1 - 1.3e-20 73.7 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDS30918.1 - 6.3e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Y_phosphatase3 PF13350.6 CDS30918.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDS30918.1 - 0.0072 16.5 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate YopE_N PF09020.10 CDS30918.1 - 0.026 14.8 0.1 0.073 13.3 0.1 1.7 1 0 0 1 1 1 0 YopE, N terminal DSPc PF00782.20 CDS30918.1 - 0.03 14.1 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CRAL_TRIO_N PF03765.15 CDS30918.1 - 0.084 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain TRAPP PF04051.16 CDS30921.1 - 6e-31 107.1 0.0 7.6e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ELO PF01151.18 CDS30923.1 - 7.3e-60 202.6 29.9 9e-60 202.3 29.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Ras PF00071.22 CDS30925.1 - 3.3e-48 163.4 0.0 4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30925.1 - 1.6e-29 102.6 0.0 2.2e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30925.1 - 2.4e-11 43.4 0.1 4.4e-11 42.5 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 CDS30925.1 - 4.8e-06 26.2 0.1 0.0041 16.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDS30925.1 - 6.1e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS30925.1 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CDS30925.1 - 0.056 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 CDS30925.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CDS30925.1 - 0.12 11.5 0.0 6.7 5.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF1682 PF07946.14 CDS30926.1 - 2.9e-91 306.0 0.1 3.5e-91 305.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4821 PF16092.5 CDS30926.1 - 0.081 12.5 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Presenilin PF01080.17 CDS30926.1 - 4 6.1 7.2 7.5 5.2 7.2 1.4 1 0 0 1 1 1 0 Presenilin Cupin_4 PF08007.12 CDS30927.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 CDS30927.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.0 2 1 0 2 2 2 0 Cupin-like domain ADAM_CR PF08516.12 CDS30928.1 - 3.3e-16 59.7 9.8 3.3e-16 59.7 9.8 3.7 3 0 0 3 3 3 1 ADAM cysteine-rich Pep_M12B_propep PF01562.19 CDS30928.1 - 3.1e-13 50.1 0.0 3.1e-13 50.1 0.0 2.8 4 0 0 4 4 4 1 Reprolysin family propeptide Disintegrin PF00200.23 CDS30928.1 - 6.9e-12 46.0 13.9 6.9e-12 46.0 13.9 5.6 7 0 0 7 7 7 1 Disintegrin Reprolysin PF01421.19 CDS30928.1 - 9.9e-10 38.6 0.4 5.5e-07 29.7 0.3 2.6 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease EGF_2 PF07974.13 CDS30928.1 - 5.7e-05 23.4 4.5 5.7e-05 23.4 4.5 4.3 6 0 0 6 6 6 1 EGF-like domain RTA1 PF04479.13 CDS30928.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 RTA1 like protein PI3_PI4_kinase PF00454.27 CDS30932.1 - 2.6e-30 106.1 0.0 1.3e-20 74.3 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CDS30932.1 - 0.14 11.4 0.4 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Ig_3 PF13927.6 CDS30934.1 - 7.5e-51 170.7 7.5 2.8e-10 40.6 0.1 11.8 11 1 0 11 11 11 8 Immunoglobulin domain fn3 PF00041.21 CDS30934.1 - 2.1e-49 165.8 16.6 6.5e-14 52.1 0.4 8.2 7 3 0 7 7 6 5 Fibronectin type III domain I-set PF07679.16 CDS30934.1 - 3.6e-39 132.7 3.3 4.8e-08 33.0 0.0 11.5 10 1 0 10 10 10 8 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS30934.1 - 5.4e-20 71.5 4.3 0.024 14.9 0.0 11.8 11 1 1 12 12 12 4 Immunoglobulin domain ig PF00047.25 CDS30934.1 - 1.1e-18 67.2 3.7 2.7e-05 24.2 0.0 9.4 11 0 0 11 11 9 4 Immunoglobulin domain V-set PF07686.17 CDS30934.1 - 2.5e-14 53.4 5.5 0.011 15.9 0.0 9.5 9 1 0 9 9 9 3 Immunoglobulin V-set domain Pur_ac_phosph_N PF16656.5 CDS30934.1 - 2.4e-09 37.6 9.1 1.8e-05 25.2 0.4 5.2 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CDS30934.1 - 1.6e-06 27.6 0.0 0.023 14.3 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 CDS30934.1 - 0.013 15.7 0.0 21 5.5 0.0 4.2 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Interfer-bind PF09294.10 CDS30934.1 - 0.023 15.0 0.5 0.41 11.0 0.1 3.2 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III DUF3659 PF12396.8 CDS30934.1 - 0.081 12.8 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Ig_C17orf99 PF17736.1 CDS30934.1 - 0.11 12.6 0.2 25 5.0 0.0 4.6 5 0 0 5 5 5 0 C17orf99 Ig domain tRNA-synt_1d PF00750.19 CDS30937.1 - 4.7e-125 417.1 0.4 7e-125 416.6 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDS30937.1 - 6.2e-27 94.1 0.3 3.7e-26 91.7 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CDS30937.1 - 3.1e-21 75.8 0.1 9.3e-21 74.2 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CDS30937.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_2 PF00152.20 CDS30938.2 - 2.1e-92 309.6 0.0 3.6e-92 308.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDS30938.2 - 2.5e-14 53.0 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 CDS30938.2 - 0.016 14.8 0.1 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 tRNA_anti-like TOBE PF03459.17 CDS30938.2 - 0.04 14.2 0.2 3.1 8.2 0.0 3.0 4 0 0 4 4 4 0 TOBE domain DUF4539 PF15072.6 CDS30938.2 - 0.041 13.9 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.6 CDS30938.2 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2 PF00152.20 CDS30939.1 - 7.5e-16 58.1 0.0 8.8e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Romo1 PF10247.9 CDS30940.1 - 6.8e-27 93.6 18.9 8.4e-27 93.3 18.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 CDS30940.1 - 0.0087 16.4 8.5 0.011 16.2 8.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.22 CDS30941.1 - 1.5e-57 193.7 0.3 1.8e-57 193.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30941.1 - 1.9e-33 115.2 0.2 2.8e-33 114.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30941.1 - 9.3e-12 44.7 0.1 1.2e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS30941.1 - 1e-05 25.6 0.2 1.5e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS30941.1 - 0.0038 17.2 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDS30941.1 - 0.0066 16.0 0.4 0.03 13.9 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDS30941.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CDS30941.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CDS30941.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS30941.1 - 0.029 14.6 0.1 0.071 13.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDS30941.1 - 0.042 13.1 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MCM PF00493.23 CDS30941.1 - 0.043 12.9 0.1 0.12 11.5 0.0 1.8 1 1 0 2 2 2 0 MCM P-loop domain AAA_5 PF07728.14 CDS30941.1 - 0.048 13.7 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDS30941.1 - 0.054 14.0 0.0 0.099 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 CDS30941.1 - 0.081 12.4 0.1 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 CDS30941.1 - 0.083 12.3 0.1 0.25 10.7 0.0 1.8 3 0 0 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 CDS30941.1 - 0.14 12.4 0.1 1.1 9.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 CDS30942.1 - 5.2e-60 201.7 0.7 6.1e-60 201.5 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS30942.1 - 1.2e-33 115.9 0.3 1.9e-33 115.2 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS30942.1 - 1.4e-12 47.4 0.2 1.8e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS30942.1 - 1e-07 32.1 0.2 1.7e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS30942.1 - 7e-06 26.0 0.2 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CDS30942.1 - 0.0016 18.0 0.3 0.0051 16.4 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDS30942.1 - 0.0044 17.3 0.0 0.028 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CDS30942.1 - 0.011 15.1 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.14 CDS30942.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 CDS30942.1 - 0.06 12.8 0.1 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CDS30942.1 - 0.1 12.1 0.1 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 CDS30942.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 CDS30942.1 - 0.13 12.7 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_32 PF13654.6 CDS30942.1 - 0.13 11.0 0.0 0.36 9.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain TRAM_LAG1_CLN8 PF03798.16 CDS30943.1 - 1.3e-29 103.4 26.0 1.3e-29 103.4 26.0 1.4 2 0 0 2 2 2 1 TLC domain Peptidase_M1 PF01433.20 CDS30944.1 - 6.7e-82 274.3 0.7 1e-81 273.7 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDS30944.1 - 2.8e-68 230.8 0.0 4.7e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDS30944.1 - 1.2e-39 136.4 0.0 1.9e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain EF-hand_1 PF00036.32 CDS30945.1 - 1.1e-33 112.2 8.9 1.1e-08 34.0 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS30945.1 - 7.6e-32 109.6 8.3 2.1e-14 53.7 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS30945.1 - 1.9e-28 96.6 8.1 1.5e-08 33.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CDS30945.1 - 6.2e-28 94.3 3.1 5.2e-08 32.2 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDS30945.1 - 2e-25 88.4 11.6 9.9e-10 38.1 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDS30945.1 - 1.2e-08 35.1 0.1 0.0056 17.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS30945.1 - 1.9e-08 34.6 0.1 0.0053 17.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS30945.1 - 2.2e-08 34.0 0.1 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDS30945.1 - 6.5e-05 23.0 0.9 0.071 13.3 0.3 3.3 3 1 0 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 CDS30945.1 - 0.00023 21.1 1.4 0.01 15.7 0.0 3.2 2 2 2 4 4 4 1 Caleosin related protein EF-hand_11 PF08976.11 CDS30945.1 - 0.00078 20.3 0.0 0.0029 18.4 0.0 1.7 1 1 1 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 CDS30945.1 - 0.0015 18.3 0.2 0.024 14.5 0.0 2.5 2 1 0 2 2 2 1 EF hand UBA_6 PF18039.1 CDS30945.1 - 0.026 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain EF-hand_14 PF17959.1 CDS30945.1 - 0.029 14.7 0.1 12 6.3 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Homeodomain PF00046.29 CDS30945.1 - 0.053 13.4 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Homeodomain CCD48 PF15799.5 CDS30945.1 - 0.063 11.6 0.0 1.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 SAP PF02037.27 CDS30945.1 - 0.08 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 SAP domain PMBR PF09373.10 CDS30945.1 - 0.15 12.3 0.0 19 5.6 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat wnt PF00110.19 CDS30947.1 - 7.1e-94 314.9 15.6 9.2e-94 314.5 15.6 1.1 1 0 0 1 1 1 1 wnt family TORC_N PF12884.7 CDS30948.1 - 2.7e-08 34.5 0.0 2.7e-08 34.5 0.0 3.7 4 0 0 4 4 4 1 Transducer of regulated CREB activity, N terminus Otopetrin PF03189.13 CDS30949.1 - 3.6e-101 339.2 21.9 1.9e-74 251.1 7.7 2.4 1 1 1 2 2 2 2 Otopetrin BCLP PF12304.8 CDS30949.1 - 0.045 13.3 1.8 0.1 12.2 1.8 1.5 1 0 0 1 1 1 0 Beta-casein like protein Ac110_PIF PF07280.11 CDS30949.1 - 0.13 12.1 4.6 0.58 10.0 4.6 2.3 1 0 0 1 1 1 0 Per os infectivity factor AC110 DUF4199 PF13858.6 CDS30949.1 - 0.64 10.4 22.1 1.8 8.9 10.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) Pkinase PF00069.25 CDS30952.1 - 7.5e-54 182.8 0.0 1.3e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30952.1 - 8.4e-22 77.7 0.0 2.6e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pepdidase_M14_N PF18027.1 CDS30952.1 - 3.6e-16 59.5 0.5 1e-15 58.0 0.5 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 CDS30952.1 - 2.7e-13 50.4 0.0 6.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase APH PF01636.23 CDS30952.1 - 0.00025 21.1 0.0 0.013 15.5 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family NST1 PF13945.6 CDS30952.1 - 0.49 10.5 11.4 1.7 8.8 11.4 1.9 1 0 0 1 1 1 0 Salt tolerance down-regulator PWWP PF00855.17 CDS30954.1 - 3.2e-12 46.7 0.1 3.2e-12 46.7 0.1 3.3 3 0 0 3 3 3 1 PWWP domain LEDGF PF11467.8 CDS30954.1 - 7.2e-05 22.4 1.4 7.2e-05 22.4 1.4 2.7 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) DUF4203 PF13886.6 CDS30955.1 - 0.04 13.6 2.1 0.051 13.2 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF202 PF02656.15 CDS30955.1 - 0.084 13.3 1.8 0.14 12.6 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) NapE PF06796.11 CDS30955.1 - 0.15 11.6 0.7 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Gemin6 PF06372.12 CDS30956.1 - 0.016 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Gemin6 protein Pkinase PF00069.25 CDS30957.1 - 2e-59 201.1 0.0 2.4e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30957.1 - 2.4e-25 89.3 0.0 3.1e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS30957.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS30957.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDS30957.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CDS30957.1 - 0.11 11.3 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Glu_dehyd_C PF16912.5 CDS30957.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Bap31 PF05529.12 CDS30958.1 - 4.6e-39 133.4 1.1 7.5e-39 132.7 1.1 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CDS30958.1 - 2.1e-11 43.6 7.9 2.1e-11 43.6 7.9 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain EzrA PF06160.12 CDS30958.1 - 0.0002 19.7 2.8 0.00028 19.2 2.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Filament PF00038.21 CDS30958.1 - 0.00026 20.7 3.7 0.00041 20.0 3.7 1.3 1 0 0 1 1 1 1 Intermediate filament protein HALZ PF02183.18 CDS30958.1 - 0.003 17.8 5.1 0.7 10.2 0.3 2.3 2 0 0 2 2 2 2 Homeobox associated leucine zipper APG6_N PF17675.1 CDS30958.1 - 0.066 13.7 8.2 0.13 12.7 8.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CDS30958.1 - 0.086 12.9 1.0 0.14 12.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CDS30958.1 - 0.093 12.8 14.3 0.22 11.6 14.2 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GvpK PF05121.12 CDS30958.1 - 0.16 12.0 2.2 6 7.0 0.1 3.0 2 1 1 3 3 3 0 Gas vesicle protein K Sec34 PF04136.15 CDS30958.1 - 0.38 10.6 4.7 0.87 9.5 3.7 1.9 2 0 0 2 2 2 0 Sec34-like family HsbA PF12296.8 CDS30958.1 - 0.4 11.1 6.4 2 8.8 5.2 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A ERM PF00769.19 CDS30958.1 - 0.4 10.5 12.6 0.52 10.1 12.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.15 CDS30958.1 - 0.49 10.2 6.7 0.93 9.3 1.6 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF1843 PF08898.10 CDS30958.1 - 0.65 10.5 4.6 0.27 11.8 0.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1843) Atg14 PF10186.9 CDS30958.1 - 1.4 7.9 8.1 1.2 8.1 6.9 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 CDS30958.1 - 1.5 9.1 8.9 1.4 9.1 7.7 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Miff PF05644.11 CDS30959.1 - 2.7e-06 27.3 1.5 8.4e-06 25.6 0.0 2.2 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff Laminin_II PF06009.12 CDS30959.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain II BLOC1_2 PF10046.9 CDS30961.1 - 0.002 18.4 16.7 0.019 15.2 5.5 2.7 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 CDS30961.1 - 0.0033 18.0 14.6 0.32 11.6 1.2 3.1 1 1 1 2 2 2 2 SlyX TMF_DNA_bd PF12329.8 CDS30961.1 - 0.0099 15.9 10.2 0.0099 15.9 10.2 2.7 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 CDS30961.1 - 0.012 15.7 16.0 0.012 15.7 16.0 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CDS30961.1 - 0.014 15.6 14.7 0.014 15.6 14.7 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CDS30961.1 - 0.016 15.2 16.2 0.067 13.2 5.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CDS30961.1 - 0.022 15.3 11.6 0.022 15.3 11.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rootletin PF15035.6 CDS30961.1 - 0.023 14.7 8.6 0.023 14.7 8.6 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Flagellin_N PF00669.20 CDS30961.1 - 0.029 14.5 2.4 0.029 14.5 2.4 2.6 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region YjcZ PF13990.6 CDS30961.1 - 0.04 13.3 7.7 0.062 12.7 7.7 1.2 1 0 0 1 1 1 0 YjcZ-like protein NPV_P10 PF05531.12 CDS30961.1 - 0.052 14.0 8.5 3.3 8.2 3.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.12 CDS30961.1 - 0.074 13.3 4.0 0.19 12.0 2.6 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Fib_alpha PF08702.10 CDS30961.1 - 0.082 13.1 21.9 0.083 13.1 8.9 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.6 CDS30961.1 - 0.1 12.3 18.7 0.12 12.1 4.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FAM184 PF15665.5 CDS30961.1 - 0.14 11.9 19.8 0.02 14.7 13.1 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 CDS30961.1 - 0.21 10.4 21.2 0.079 11.8 17.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 CDS30961.1 - 0.27 9.7 1.0 0.27 9.7 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 CDS30961.1 - 0.27 11.0 22.6 1.2 8.9 19.4 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Ribosomal_S13 PF00416.22 CDS30961.1 - 0.28 11.6 12.9 0.22 11.9 2.1 2.3 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Matrilin_ccoil PF10393.9 CDS30961.1 - 0.35 10.8 6.3 3.2 7.7 1.6 3.9 2 2 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 CDS30961.1 - 0.37 10.8 14.4 0.84 9.7 7.8 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YqhG PF11079.8 CDS30961.1 - 0.39 9.6 7.8 0.9 8.4 7.8 1.5 1 1 0 1 1 1 0 Bacterial protein YqhG of unknown function Ndc1_Nup PF09531.10 CDS30961.1 - 0.46 9.1 4.9 0.59 8.8 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAA_hydro_N_2 PF18288.1 CDS30961.1 - 0.57 10.6 2.5 2.1 8.8 0.4 2.8 2 1 2 4 4 2 0 Fumarylacetoacetase N-terminal domain 2 DUF3450 PF11932.8 CDS30961.1 - 1 8.6 18.2 3 7.1 17.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) NRBF2 PF08961.10 CDS30961.1 - 1.1 8.8 18.4 0.37 10.4 6.4 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator PAF-AH_p_II PF03403.13 CDS30961.1 - 1.2 7.6 11.1 0.21 10.1 7.1 1.8 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II COG5 PF10392.9 CDS30961.1 - 1.2 9.3 14.1 0.56 10.4 8.1 3.1 2 2 2 4 4 4 0 Golgi transport complex subunit 5 Uso1_p115_C PF04871.13 CDS30961.1 - 1.4 9.3 18.2 0.17 12.3 4.8 2.8 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 CDS30961.1 - 1.5 8.9 19.3 0.65 10.1 16.8 1.7 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CDS30961.1 - 1.6 8.2 17.2 4 6.9 17.2 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 CDS30961.1 - 2.1 8.3 14.5 0.75 9.7 3.9 2.8 1 1 1 2 2 2 0 Prefoldin subunit YabA PF06156.13 CDS30961.1 - 2.4 8.8 20.4 0.39 11.4 6.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA LUC7 PF03194.15 CDS30961.1 - 2.8 7.5 17.1 3.8 7.1 17.1 1.4 1 1 0 1 1 1 0 LUC7 N_terminus TMPIT PF07851.13 CDS30961.1 - 3.7 6.7 13.4 6.8 5.8 13.3 1.6 1 1 0 1 1 1 0 TMPIT-like protein Sec20 PF03908.13 CDS30961.1 - 3.8 7.5 10.8 9.8 6.2 7.7 2.6 1 1 2 3 3 3 0 Sec20 DUF745 PF05335.13 CDS30961.1 - 3.9 7.2 12.7 5.5 6.7 9.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.9 CDS30961.1 - 4.5 6.3 17.3 4.4 6.3 16.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 CDS30961.1 - 4.9 7.4 16.3 0.67 10.2 7.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tweety PF04906.13 CDS30961.1 - 5.1 5.7 7.1 6.8 5.2 6.6 1.4 1 1 0 1 1 1 0 Tweety DUF4795 PF16043.5 CDS30961.1 - 5.8 6.5 16.4 15 5.1 16.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4706 PF15797.5 CDS30961.1 - 6.3 7.4 12.6 21 5.7 6.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) DUF948 PF06103.11 CDS30961.1 - 6.4 7.1 11.4 14 6.0 4.3 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) dCache_1 PF02743.18 CDS30961.1 - 6.5 6.4 10.2 12 5.6 9.3 2.0 1 1 0 1 1 1 0 Cache domain bZIP_1 PF00170.21 CDS30961.1 - 7.7 6.7 17.5 0.74 10.0 1.9 3.3 4 1 0 4 4 2 0 bZIP transcription factor MAS20 PF02064.15 CDS30961.1 - 7.8 6.6 10.4 1.3 9.2 6.6 1.6 2 0 0 2 2 1 0 MAS20 protein import receptor HAUS6_N PF14661.6 CDS30961.1 - 8.7 5.8 16.7 2.3 7.8 9.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Fmp27_WPPW PF10359.9 CDS30961.1 - 8.9 5.0 18.9 0.28 10.0 6.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Bclx_interact PF08945.10 CDS30962.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain GRAM PF02893.20 CDS30963.1 - 1.7e-07 31.1 0.1 3.4e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 GRAM domain DASH_Dad3 PF08656.10 CDS30963.1 - 0.13 12.3 1.2 0.47 10.6 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Ank_2 PF12796.7 CDS30964.1 - 4.6e-07 30.3 0.1 5.3e-05 23.7 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS30964.1 - 7.2e-05 23.3 0.3 0.0012 19.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDS30964.1 - 0.09 13.3 2.1 6.8 7.3 0.1 3.4 3 1 0 3 3 3 0 Ankyrin repeat Tetraspanin PF00335.20 CDS30966.1 - 7.9e-16 58.5 16.5 1.6e-15 57.5 16.4 1.5 1 1 0 1 1 1 1 Tetraspanin family Tetraspanin PF00335.20 CDS30967.1 - 2.2e-21 76.6 17.5 3.6e-21 76.0 17.2 1.4 1 1 0 1 1 1 1 Tetraspanin family LRRC37AB_C PF14914.6 CDS30967.1 - 0.11 12.4 0.8 0.34 10.8 0.8 1.9 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Tetraspanin PF00335.20 CDS30968.1 - 1.2e-26 93.8 23.4 2.3e-26 92.9 23.4 1.4 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 CDS30968.1 - 1.7 8.4 13.9 3.4 7.4 0.2 2.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Phage_Gp23 PF10669.9 CDS30968.1 - 4.6 7.6 6.8 0.31 11.4 1.1 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Tetraspanin PF00335.20 CDS30969.1 - 3.7e-22 79.2 26.2 6.2e-22 78.4 24.8 1.8 1 1 0 1 1 1 1 Tetraspanin family CDC24 PF06395.11 CDS30969.1 - 0.07 13.4 1.0 2.8 8.2 0.1 2.5 2 0 0 2 2 2 0 CDC24 Calponin Proton_antipo_C PF01010.19 CDS30969.1 - 0.12 12.0 7.0 0.19 11.4 4.8 2.1 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus LRRC37AB_C PF14914.6 CDS30969.1 - 4.1 7.3 13.3 0.11 12.4 2.3 2.7 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Claudin_2 PF13903.6 CDS30969.1 - 6.8 6.4 16.4 0.31 10.8 2.3 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction CK_II_beta PF01214.18 CDS30972.1 - 0.029 14.2 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Casein kinase II regulatory subunit CN_hydrolase PF00795.22 CDS30974.1 - 1.3e-44 152.6 0.0 1.7e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HIT PF01230.23 CDS30974.1 - 1.3e-20 74.0 0.0 3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDS30974.1 - 0.0068 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.7 CDS30975.1 - 8.1e-09 35.6 10.4 0.00041 20.7 3.4 3.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS30975.1 - 3.5e-08 33.1 6.1 4.1e-07 29.7 2.1 3.2 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 CDS30975.1 - 0.0001 22.3 9.7 1.3 9.9 1.1 5.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 CDS30975.1 - 0.0002 20.9 0.2 0.0021 17.6 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CDS30975.1 - 0.008 16.2 5.1 1.3 9.2 0.7 4.3 5 0 0 5 5 5 1 Leucine Rich repeat Clathrin_lg_ch PF01086.17 CDS30976.1 - 5.5e-24 85.5 4.3 6.9e-24 85.2 4.3 1.1 1 0 0 1 1 1 1 Clathrin light chain zf-C2H2 PF00096.26 CDS30977.1 - 1.2e-11 44.4 24.0 0.0037 17.6 3.9 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS30977.1 - 3.4e-11 43.0 20.5 4.3e-05 23.8 0.3 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS30977.1 - 1.1e-07 32.1 19.3 0.056 14.3 0.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDS30977.1 - 0.00027 21.2 6.4 0.0013 19.0 3.7 2.3 2 0 0 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 CDS30977.1 - 0.0017 19.0 8.2 1.3 9.7 0.2 4.3 1 1 3 4 4 4 1 FOXP coiled-coil domain zf-TRAF PF02176.18 CDS30977.1 - 0.12 13.1 13.1 0.26 12.0 1.9 3.0 2 1 0 2 2 2 0 TRAF-type zinc finger zf-RAG1 PF10426.9 CDS30977.1 - 0.14 12.4 0.4 30 4.9 0.2 2.6 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_jaz PF12171.8 CDS30977.1 - 1.3 9.4 9.6 5.4 7.4 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RPAP2_Rtr1 PF04181.13 CDS30977.1 - 8.6 6.8 11.0 1.2e+04 -3.3 11.0 3.7 1 1 0 1 1 1 0 Rtr1/RPAP2 family Annexin PF00191.20 CDS30978.2 - 1.3e-170 553.7 20.4 4.5e-20 71.5 0.1 10.1 10 0 0 10 10 10 10 Annexin Acetyltransf_11 PF13720.6 CDS30978.2 - 0.0055 17.1 1.6 9.8 6.7 0.0 5.5 7 0 0 7 7 7 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lip_prot_lig_C PF10437.9 CDS30978.2 - 0.015 15.2 0.1 54 3.9 0.0 4.3 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus DUF2877 PF11392.8 CDS30978.2 - 0.088 13.5 1.4 76 4.1 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2877) Amdase PF17645.1 CDS30978.2 - 0.18 11.4 0.4 1.7 8.2 0.0 2.8 4 1 1 5 5 5 0 Arylmalonate decarboxylase SAM_Exu PF18609.1 CDS30978.2 - 0.2 11.7 3.2 3.3 7.8 0.0 4.4 4 0 0 4 4 4 0 Exuperantia SAM-like domain Ribosomal_S24e PF01282.19 CDS30979.1 - 1.6e-34 117.6 0.8 2.1e-34 117.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e CK_II_beta PF01214.18 CDS30980.2 - 2.1e-78 262.3 0.0 2.7e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_S17 PF00366.20 CDS30982.2 - 1.3e-06 28.4 0.3 2.4e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 MRPL52 PF18699.1 CDS30983.1 - 8.5e-13 48.3 1.2 1e-12 48.0 1.2 1.1 1 0 0 1 1 1 1 Mitoribosomal protein mL52 Trypsin PF00089.26 CDS30984.1 - 2.6e-60 204.0 0.1 6.7e-58 196.1 0.0 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CDS30984.1 - 9.2e-05 23.4 0.0 0.00021 22.2 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CDS30984.1 - 0.00071 20.0 0.0 0.0062 16.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) VHS PF00790.19 CDS30985.1 - 4.5e-30 104.4 0.0 9.7e-29 100.0 0.0 2.7 2 1 0 2 2 2 1 VHS domain GGA_N-GAT PF18308.1 CDS30985.1 - 3.1e-15 55.5 0.4 3.1e-15 55.5 0.4 2.1 2 0 0 2 2 2 1 GGA N-GAT domain GAT PF03127.14 CDS30985.1 - 9.3e-10 38.7 0.3 3.2e-08 33.8 0.0 3.0 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 CDS30985.1 - 4e-09 36.8 1.4 6.2e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF4125 PF13526.6 CDS30985.1 - 0.097 12.3 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) SNAP PF14938.6 CDS30986.1 - 2.8e-16 59.8 13.7 4e-16 59.3 13.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CDS30986.1 - 2.8e-05 23.8 8.7 0.48 10.6 0.1 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS30986.1 - 9.2e-05 22.3 14.7 2.4 8.5 0.1 7.4 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDS30986.1 - 0.00066 19.9 15.0 0.083 13.2 0.7 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat Clathrin PF00637.20 CDS30986.1 - 0.0089 15.9 3.8 1.7 8.6 0.3 3.4 3 1 0 4 4 4 2 Region in Clathrin and VPS TPR_8 PF13181.6 CDS30986.1 - 0.027 14.7 11.6 1.3 9.4 0.1 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS30986.1 - 0.038 14.8 11.3 11 7.1 0.7 5.8 2 1 5 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS30986.1 - 0.047 13.5 14.8 1.5 8.7 0.3 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat YmgB PF10798.8 CDS30986.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF2225 PF09986.9 CDS30986.1 - 1.3 8.7 7.1 0.43 10.3 3.8 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) CCSMST1 PF15013.6 CDS30987.1 - 1.5e-08 34.7 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 CCSMST1 family ATP-sulfurylase PF01747.17 CDS30988.2 - 8.5e-67 224.7 0.0 1.2e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CDS30988.2 - 1.2e-62 210.4 0.0 3.7e-37 127.6 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase PUA_2 PF14306.6 CDS30988.2 - 1.1e-41 142.2 0.0 2.5e-41 141.0 0.0 1.6 2 0 0 2 2 2 1 PUA-like domain AAA_18 PF13238.6 CDS30988.2 - 0.00048 20.7 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS30988.2 - 0.00063 19.9 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDS30988.2 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CTP_transf_like PF01467.26 CDS30988.2 - 0.26 11.5 0.5 8.7 6.5 0.3 2.5 2 0 0 2 2 2 0 Cytidylyltransferase-like DUF4446 PF14584.6 CDS30989.1 - 0.037 14.0 1.1 0.089 12.8 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) XhlA PF10779.9 CDS30989.1 - 0.25 11.6 3.1 0.64 10.3 3.1 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Antimicrobial25 PF16839.5 CDS30990.1 - 2 8.6 11.2 7.4 6.8 6.2 2.8 2 0 0 2 2 2 0 Nematode antimicrobial peptide DUF4716 PF15837.5 CDS30991.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) Pkinase PF00069.25 CDS30992.1 - 5.7e-72 242.2 0.0 7.3e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30992.1 - 3.4e-33 115.0 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS30992.1 - 0.0041 17.1 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PKD_channel PF08016.12 CDS30993.1 - 3.2e-82 276.5 14.9 3.2e-82 276.5 14.9 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 CDS30993.1 - 8.6e-15 54.6 38.9 1.5e-14 53.9 32.1 2.7 3 1 0 3 3 3 2 Ion transport protein EF-hand_8 PF13833.6 CDS30993.1 - 0.0015 18.3 0.0 0.0065 16.3 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS30993.1 - 0.1 12.6 0.4 0.86 9.7 0.4 2.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CDS30993.1 - 1.7 8.4 5.8 0.21 11.2 0.5 2.4 3 0 0 3 3 3 0 EF hand Hid1 PF12722.7 CDS30995.1 - 4.2e-232 772.7 6.9 1.2e-191 638.9 0.7 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CDS30995.1 - 2.4e-205 683.7 0.0 5e-203 676.0 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein GlutR_dimer PF00745.20 CDS30996.1 - 0.0016 18.9 5.2 0.0016 18.9 5.2 3.9 4 1 1 5 5 5 1 Glutamyl-tRNAGlu reductase, dimerisation domain Hydantoinase_A PF01968.18 CDS30996.1 - 0.033 13.4 0.2 0.059 12.6 0.2 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase OmpH PF03938.14 CDS30996.1 - 1.6 9.0 23.2 0.79 10.1 9.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PX PF00787.24 CDS30997.1 - 2.3e-25 88.8 0.0 2.8e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 CDS30998.1 - 1.4e-23 83.7 0.2 1.5e-21 77.0 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS30998.1 - 2.5e-16 59.7 0.0 2.8e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDS30998.1 - 0.013 15.4 0.1 0.07 13.0 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CDS30998.1 - 0.035 13.5 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M24 PF00557.24 CDS30999.1 - 4.6e-43 147.4 0.1 5.9e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CDS30999.1 - 1e-18 67.3 7.7 2.9e-18 65.9 7.7 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CDS30999.1 - 1.2e-05 25.3 5.7 3.1e-05 24.0 5.7 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 CDS30999.1 - 0.037 13.9 6.0 0.092 12.6 6.0 1.7 1 0 0 1 1 1 0 HIT zinc finger OAD_gamma PF04277.13 CDS31001.1 - 0.026 15.1 0.0 0.046 14.3 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-RING_2 PF13639.6 CDS31002.1 - 2e-14 53.6 24.9 4.7e-11 42.8 5.3 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CDS31002.1 - 8.9e-10 38.3 25.7 4.7e-09 36.0 7.0 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS31002.1 - 1.8e-09 37.3 24.6 3.1e-09 36.5 6.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS31002.1 - 8.4e-09 35.2 21.3 2.5e-08 33.7 3.0 3.1 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS31002.1 - 4.4e-08 33.3 20.4 1.5e-06 28.4 6.0 2.7 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS31002.1 - 1.5e-07 31.2 4.4 1.5e-07 31.2 4.4 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS31002.1 - 3.6e-07 30.1 5.2 3.6e-07 30.1 5.2 4.0 3 1 1 4 4 4 2 RING-type zinc-finger Prok-RING_4 PF14447.6 CDS31002.1 - 0.00013 21.8 3.6 0.00013 21.8 3.6 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDS31002.1 - 0.00041 20.3 13.1 0.014 15.4 2.2 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDS31002.1 - 0.0005 19.6 3.3 0.0005 19.6 3.3 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDS31002.1 - 0.0007 19.3 6.2 0.0007 19.3 6.2 3.0 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_6 PF14835.6 CDS31002.1 - 0.007 16.2 1.4 0.007 16.2 1.4 2.6 2 1 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDS31002.1 - 0.0085 16.2 5.4 0.0085 16.2 5.4 3.4 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING PHD PF00628.29 CDS31002.1 - 0.01 15.7 8.7 0.01 15.7 8.7 2.5 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.6 CDS31002.1 - 0.066 12.8 1.0 0.066 12.8 1.0 3.4 5 0 0 5 5 5 0 PHD-finger zf-RING_10 PF16685.5 CDS31002.1 - 0.088 13.0 16.3 0.075 13.2 2.4 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDS31002.1 - 0.12 12.1 0.6 0.12 12.1 0.6 3.5 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 CDS31002.1 - 0.36 10.8 4.7 0.85 9.6 2.2 2.4 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Histone PF00125.24 CDS31003.1 - 1.3e-23 83.7 0.1 2e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS31003.1 - 0.002 18.4 0.1 0.0035 17.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDS31003.1 - 0.0064 16.6 0.3 0.1 12.8 0.1 2.2 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Coprogen_oxidas PF01218.18 CDS31004.1 - 1.2e-128 428.0 0.2 1.3e-128 427.8 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase WD40 PF00400.32 CDS31005.1 - 2.8e-08 34.3 13.0 0.00029 21.6 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31005.1 - 3.7e-07 30.4 0.0 0.035 14.4 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS31005.1 - 0.0088 15.0 0.1 0.14 11.1 0.0 2.6 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Band_7 PF01145.25 CDS31008.1 - 1.5e-22 80.5 1.5 2.5e-22 79.8 0.0 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family TPR_2 PF07719.17 CDS31008.1 - 2.4e-11 42.8 4.7 0.00025 20.9 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31008.1 - 6.7e-10 39.0 7.0 0.00048 20.7 0.1 6.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS31008.1 - 7.1e-09 36.0 0.8 0.003 18.0 0.2 4.0 1 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31008.1 - 2.5e-08 33.5 6.4 0.2 12.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS31008.1 - 4.5e-08 33.6 2.6 0.044 14.4 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS31008.1 - 2.3e-06 27.2 5.3 0.009 15.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS31008.1 - 5.3e-06 26.0 6.1 0.00062 19.4 0.5 3.6 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 CDS31008.1 - 0.00056 20.0 0.1 0.026 14.7 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31008.1 - 0.0041 17.1 0.4 4.2 7.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CDS31008.1 - 0.021 14.4 0.3 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 CDS31008.1 - 0.039 14.6 1.2 68 4.4 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.8 CDS31008.1 - 0.052 12.5 0.1 0.052 12.5 0.1 3.0 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 CDS31008.1 - 0.054 13.9 1.7 17 6.1 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31008.1 - 0.79 10.1 12.5 1.5 9.1 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TRAPP PF04051.16 CDS31009.1 - 6.3e-24 84.4 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PHD PF00628.29 CDS31009.1 - 2.6e-09 36.8 3.8 5.1e-09 35.9 3.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDS31009.1 - 0.0015 18.0 2.9 0.0031 17.0 2.9 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CDS31009.1 - 0.029 14.2 0.6 0.029 14.2 0.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CDS31009.1 - 0.068 13.3 7.1 0.13 12.4 7.1 1.5 1 0 0 1 1 1 0 PHD-finger Spond_N PF06468.13 CDS31010.1 - 3.4e-46 157.8 0.1 5.5e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Spondin_N Kunitz_BPTI PF00014.23 CDS31010.1 - 1.2e-23 83.1 19.6 1.5e-13 50.8 5.5 2.9 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain TSP_1 PF00090.19 CDS31010.1 - 2.3e-18 66.1 24.8 2.4e-08 34.1 6.5 4.2 3 0 0 3 3 3 3 Thrombospondin type 1 domain SNAD4 PF18750.1 CDS31010.1 - 0.074 13.2 1.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF3549 PF12069.8 CDS31011.1 - 0.064 12.3 2.7 0.077 12.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF4510 PF14971.6 CDS31011.1 - 0.13 12.6 6.3 0.18 12.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DIT1_PvcA PF05141.12 CDS31011.1 - 0.16 11.4 4.7 0.2 11.1 4.7 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein RisS_PPD PF16524.5 CDS31011.1 - 0.56 10.5 2.9 0.97 9.7 0.1 2.3 1 1 1 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS PP28 PF10252.9 CDS31011.1 - 1.4 9.4 13.5 0.45 11.0 7.8 2.5 1 1 1 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Spectrin PF00435.21 CDS31011.1 - 1.5 9.3 11.2 10 6.7 6.5 2.4 1 1 1 2 2 2 0 Spectrin repeat YlqD PF11068.8 CDS31011.1 - 1.7 9.0 11.7 0.33 11.3 5.8 2.0 1 1 1 2 2 2 0 YlqD protein Spc7 PF08317.11 CDS31011.1 - 1.9 7.3 17.9 2.4 7.0 17.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 CDS31011.1 - 2.4 7.4 11.3 0.16 11.3 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FliT PF05400.13 CDS31011.1 - 3.3 8.6 14.7 0.75 10.6 6.6 2.5 1 1 1 2 2 2 0 Flagellar protein FliT 7tm_1 PF00001.21 CDS31012.1 - 2.5e-52 177.8 13.7 3.8e-52 177.2 13.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS31012.1 - 6.6e-13 48.6 19.5 2.2e-10 40.3 19.5 3.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDS31012.1 - 0.00066 19.0 20.3 0.051 12.9 12.1 2.8 2 2 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.6 CDS31012.1 - 0.0011 18.8 5.4 0.0011 18.8 5.4 2.0 2 1 0 2 2 2 1 Olfactory receptor UCH PF00443.29 CDS31013.1 - 6.6e-45 153.6 0.1 1.7e-44 152.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Actin PF00022.19 CDS31014.1 - 5.2e-41 140.6 0.0 6.7e-37 127.1 0.0 3.0 1 1 0 2 2 2 2 Actin DUF493 PF04359.14 CDS31015.1 - 0.07 13.7 0.0 0.083 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF493) Transposase_1 PF01359.18 CDS31016.1 - 4.8e-26 90.4 0.0 6e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Transposase (partial DDE domain) PND PF17949.1 CDS31016.1 - 0.22 11.8 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 FANCM pseudonuclease domain Ras PF00071.22 CDS31017.2 - 6.3e-48 162.4 0.0 8.7e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS31017.2 - 1.4e-28 99.6 0.0 3.1e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS31017.2 - 1.4e-13 50.7 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS31017.2 - 3.6e-08 33.1 0.0 9.3e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS31017.2 - 1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS31017.2 - 9.8e-05 22.0 0.0 0.0002 21.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS31017.2 - 0.0002 21.3 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CDS31017.2 - 0.00038 20.0 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CDS31017.2 - 0.0054 16.5 0.1 0.11 12.3 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDS31017.2 - 0.0071 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CDS31017.2 - 0.0091 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CDS31017.2 - 0.01 16.4 0.0 0.052 14.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CDS31017.2 - 0.016 14.9 0.0 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CDS31017.2 - 0.053 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS31017.2 - 0.079 13.2 0.2 0.69 10.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain DUF3504 PF12012.8 CDS31018.1 - 1e-35 123.0 1.2 1e-35 123.0 1.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) TPT PF03151.16 CDS31020.1 - 5.3e-37 127.7 20.4 8.4e-37 127.1 20.4 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DAGAT PF03982.13 CDS31020.1 - 0.0011 17.9 0.1 0.0041 16.1 0.0 2.0 2 1 0 2 2 2 1 Diacylglycerol acyltransferase EamA PF00892.20 CDS31020.1 - 0.003 17.7 11.7 0.003 17.7 11.7 4.6 4 1 0 4 4 4 1 EamA-like transporter family Acyltransferase PF01553.21 CDS31020.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase PhoLip_ATPase_C PF16212.5 CDS31021.1 - 6.5e-48 163.7 25.0 6.5e-48 163.7 25.0 2.8 3 0 0 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDS31021.1 - 1.5e-14 54.8 4.4 1.9e-07 31.6 3.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 CDS31021.1 - 3.5e-14 52.2 3.6 1e-13 50.8 3.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDS31021.1 - 9.5e-14 51.3 0.1 3.2e-11 43.1 0.0 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDS31021.1 - 1.5e-08 34.6 0.0 7.7e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDS31021.1 - 0.0014 18.5 0.3 0.0048 16.7 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SLC12 PF03522.15 CDS31023.1 - 5.9 5.8 16.2 7.4 5.5 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Phage_antiter_Q PF06323.11 CDS31027.1 - 0.035 13.7 0.3 0.042 13.4 0.3 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q DNA_pol_phi PF04931.13 CDS31032.1 - 0.13 10.3 5.5 0.14 10.2 5.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi TT_ORF2 PF02957.15 CDS31032.1 - 0.81 10.6 7.5 0.18 12.8 4.0 1.7 2 0 0 2 2 2 0 TT viral ORF2 EutA PF06277.11 CDS31033.2 - 0.076 11.9 0.2 0.085 11.7 0.2 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA Aft1_HRR PF11787.8 CDS31033.2 - 0.22 12.7 2.5 0.31 12.3 2.5 1.3 1 0 0 1 1 1 0 Aft1 HRR domain Drf_FH1 PF06346.12 CDS31034.1 - 0.0053 16.5 11.5 0.0065 16.2 11.5 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 Zip PF02535.22 CDS31034.1 - 0.053 12.7 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAP PF07174.11 CDS31034.1 - 0.71 9.3 17.2 0.84 9.0 17.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ndc1_Nup PF09531.10 CDS31034.1 - 3.2 6.3 5.0 3.7 6.1 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CDS31034.1 - 3.6 7.0 4.8 4.3 6.8 4.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SH3_1 PF00018.28 CDS31037.1 - 1.1e-23 82.5 0.3 2e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 CDS31037.1 - 3.1e-22 78.2 0.7 6.1e-11 42.0 0.1 3.3 2 1 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 CDS31037.1 - 2.5e-17 62.7 0.0 4.5e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_2 PF07653.17 CDS31037.1 - 2.7e-17 62.2 0.0 2.6e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 CDS31037.1 - 0.06 13.8 0.0 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_3 PF08239.11 CDS31037.1 - 0.15 12.3 0.2 4.6 7.6 0.0 2.6 2 1 0 2 2 2 0 Bacterial SH3 domain SDA1 PF05285.12 CDS31038.2 - 0.014 14.8 18.1 0.025 14.0 18.1 1.4 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 CDS31038.2 - 0.13 10.0 13.1 0.2 9.4 13.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Connexin PF00029.19 CDS31038.2 - 0.19 11.5 1.2 0.41 10.4 1.2 1.7 1 0 0 1 1 1 0 Connexin Sporozoite_P67 PF05642.11 CDS31038.2 - 0.27 9.3 13.6 0.44 8.6 13.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 CDS31038.2 - 0.57 9.9 23.9 1.7 8.4 23.9 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pinin_SDK_memA PF04696.13 CDS31038.2 - 0.62 10.1 13.9 1.7 8.7 13.9 1.8 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region V_ATPase_I PF01496.19 CDS31038.2 - 0.68 7.8 4.0 1.1 7.1 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2052 PF09747.9 CDS31038.2 - 1.1 9.3 23.0 0.24 11.5 17.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S64 PF08192.11 CDS31038.2 - 1.6 7.1 8.7 2.6 6.4 8.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 CDS31038.2 - 2.2 6.4 17.7 3.2 5.9 17.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDS31038.2 - 4.7 5.3 28.3 7.3 4.7 28.3 1.2 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.9 CDS31038.2 - 6.3 6.4 20.9 12 5.4 20.9 1.4 1 0 0 1 1 1 0 DDRGK domain PRIMA1 PF16101.5 CDS31040.2 - 0.0012 18.9 1.2 0.0027 17.7 1.2 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 SET PF00856.28 CDS31041.1 - 5.9e-25 88.6 0.8 4.7e-23 82.4 0.1 3.3 2 1 0 2 2 2 1 SET domain WW PF00397.26 CDS31041.1 - 7.1e-09 35.6 5.7 7.1e-09 35.6 5.7 1.9 2 0 0 2 2 2 1 WW domain AWS PF17907.1 CDS31041.1 - 1e-07 31.9 7.6 2.6e-07 30.5 7.6 1.7 1 0 0 1 1 1 1 AWS domain PHC2_SAM_assoc PF16616.5 CDS31041.1 - 0.0067 17.2 5.5 0.0067 17.2 5.5 3.4 3 0 0 3 3 3 1 Unstructured region on Polyhomeotic-like protein 1 and 2 G-gamma PF00631.22 CDS31043.1 - 2e-07 30.9 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain Nefa_Nip30_N PF10187.9 CDS31044.1 - 1.4e-16 60.7 12.8 4.1e-16 59.2 12.8 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3292 PF11696.8 CDS31044.1 - 1.5 7.1 4.1 0.29 9.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Steroid_dh PF02544.16 CDS31045.1 - 9.4e-18 64.6 4.1 1.1e-17 64.4 4.1 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Arf PF00025.21 CDS31046.1 - 1e-72 243.3 0.0 1.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDS31046.1 - 2.5e-13 50.3 0.1 3.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDS31046.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CDS31046.1 - 6.3e-12 45.4 0.0 6.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDS31046.1 - 3.5e-11 42.9 1.8 3.6e-07 29.7 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDS31046.1 - 3.5e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS31046.1 - 0.00027 21.0 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDS31046.1 - 0.093 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 CDS31046.1 - 0.13 12.8 0.1 0.19 12.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Peptidase_M20 PF01546.28 CDS31047.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDS31047.1 - 6.8e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDS31047.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 NFACT-R_1 PF05670.13 CDS31048.1 - 2.5e-41 140.7 0.0 4.7e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain RR_TM4-6 PF06459.12 CDS31048.1 - 0.24 11.2 5.0 0.29 10.9 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CDS31048.1 - 0.61 9.4 6.1 0.77 9.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2_4 PF13894.6 CDS31049.1 - 4e-14 52.1 39.1 0.00017 22.1 0.3 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-Di19 PF05605.12 CDS31049.1 - 6.5e-11 42.3 30.7 0.00024 21.3 4.3 5.1 4 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDS31049.1 - 2e-10 40.5 43.3 0.0016 18.8 2.2 6.6 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31049.1 - 1.8e-05 25.0 35.3 0.0031 17.9 0.1 7.9 7 1 0 7 7 7 2 Zinc-finger double domain Prok-RING_1 PF14446.6 CDS31049.1 - 0.0046 16.9 0.4 0.0046 16.9 0.4 5.0 5 1 0 5 5 4 1 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.13 CDS31049.1 - 0.021 14.5 0.6 0.021 14.5 0.6 2.6 3 0 0 3 3 2 0 DNA directed RNA polymerase, 7 kDa subunit FOXP-CC PF16159.5 CDS31049.1 - 0.021 15.4 10.8 1.1 9.9 0.6 4.1 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CDS31049.1 - 0.027 14.5 30.1 0.1 12.6 1.0 6.0 6 0 0 6 6 5 0 C2H2-type zinc finger PyrI_C PF02748.15 CDS31049.1 - 0.032 14.1 8.5 19 5.3 0.0 4.9 5 1 0 5 5 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CDS31049.1 - 0.053 13.5 38.0 1.2 9.2 0.1 7.0 3 2 4 7 7 7 0 BED zinc finger FYDLN_acid PF09538.10 CDS31049.1 - 0.055 14.1 6.4 3.8 8.2 0.0 3.7 3 1 1 4 4 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.7 CDS31049.1 - 0.12 12.8 21.3 5.9 7.3 0.9 5.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.15 CDS31049.1 - 0.12 12.5 0.1 0.12 12.5 0.1 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_jaz PF12171.8 CDS31049.1 - 0.16 12.3 0.6 0.16 12.3 0.6 5.0 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding PHD PF00628.29 CDS31049.1 - 0.39 10.6 22.6 0.091 12.7 2.3 5.2 5 1 0 5 5 5 0 PHD-finger zf-met PF12874.7 CDS31049.1 - 0.51 10.8 0.0 0.51 10.8 0.0 5.3 6 0 0 6 6 4 0 Zinc-finger of C2H2 type zf-ribbon_3 PF13248.6 CDS31049.1 - 0.69 9.4 0.1 0.69 9.4 0.1 5.6 6 0 0 6 6 6 0 zinc-ribbon domain Elf1 PF05129.13 CDS31049.1 - 0.75 9.9 21.9 0.39 10.8 0.9 4.9 2 1 2 5 5 5 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 CDS31049.1 - 1.2 9.2 20.0 0.65 10.0 1.7 4.8 4 1 0 4 4 4 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 CDS31049.1 - 1.5 8.4 26.6 0.051 13.1 1.5 5.6 5 1 1 6 6 5 0 TFIIB zinc-binding DUF2318 PF10080.9 CDS31049.1 - 2.5 8.3 13.5 0.092 12.9 3.2 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-C2H2_9 PF16293.5 CDS31049.1 - 2.5 8.0 12.6 1.6 8.6 0.0 4.6 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-3CxxC_2 PF17180.4 CDS31049.1 - 3.3 8.5 19.2 1 10.1 0.6 4.8 6 0 0 6 6 4 0 Zinc-binding domain zf_C2H2_6 PF18450.1 CDS31049.1 - 3.3 7.5 0.0 3.3 7.5 0.0 5.4 6 0 0 6 6 5 0 Zinc Finger domain OrsD PF12013.8 CDS31049.1 - 3.4 8.1 20.6 8.6 6.8 0.4 5.3 2 2 3 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zinc_ribbon_15 PF17032.5 CDS31049.1 - 6.8 7.5 20.4 11 6.9 7.7 4.0 1 1 2 3 3 3 0 zinc-ribbon family DnaJ PF00226.31 CDS31050.1 - 0.0019 18.3 10.7 0.28 11.3 0.1 5.2 7 0 0 7 7 7 2 DnaJ domain zf-Tim10_DDP PF02953.15 CDS31050.1 - 1.5 8.5 7.2 3.4 7.4 0.2 3.8 4 0 0 4 4 4 0 Tim10/DDP family zinc finger CHASE6_C PF17150.4 CDS31050.1 - 4.9 7.9 11.3 79 4.0 0.0 6.1 5 3 2 7 7 7 0 C-terminal domain of two-partite extracellular sensor domain DUF842 PF05811.13 CDS31050.1 - 9.1 6.0 19.6 25 4.6 0.3 4.8 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF842) Methyltr_RsmB-F PF01189.17 CDS31051.1 - 4e-21 75.6 0.0 1.2e-20 74.1 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ribosomal_L9_N PF01281.19 CDS31051.1 - 4.1e-08 32.6 0.0 8.4e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain FtsJ PF01728.19 CDS31051.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.25 CDS31052.1 - 2.7e-64 217.1 0.0 3.7e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31052.1 - 5.2e-37 127.5 0.0 7.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDS31052.1 - 2.1e-29 101.1 23.1 4.7e-16 58.4 5.6 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CDS31052.1 - 1.2e-27 96.2 0.0 2.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CDS31052.1 - 2.6e-09 37.6 2.3 5.8e-09 36.5 2.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 CDS31052.1 - 0.007 16.7 1.9 0.007 16.7 1.9 2.9 3 0 0 3 3 3 2 C1 domain Haspin_kinase PF12330.8 CDS31052.1 - 0.015 14.2 0.1 0.026 13.5 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CDS31052.1 - 0.024 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS31052.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PHD_2 PF13831.6 CDS31052.1 - 3.4 7.3 14.4 1.1 8.8 0.6 3.2 3 0 0 3 3 3 0 PHD-finger PAC3 PF10178.9 CDS31053.1 - 1.5e-06 28.3 0.0 1.7e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 zf-C2H2 PF00096.26 CDS31054.1 - 0.018 15.5 2.6 0.018 15.5 2.6 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type PHD PF00628.29 CDS31054.1 - 0.035 14.0 14.4 0.028 14.3 10.8 2.5 2 0 0 2 2 2 0 PHD-finger DnaJ PF00226.31 CDS31055.1 - 1.6e-14 53.8 0.2 4.4e-14 52.3 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain TMEM43 PF07787.12 CDS31055.1 - 2.9 7.2 5.3 4.6 6.5 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 BAH PF01426.18 CDS31056.1 - 7.4e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain TUDOR_5 PF18359.1 CDS31056.1 - 0.00017 21.2 0.0 0.00064 19.4 0.0 2.0 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 Lipase_3 PF01764.25 CDS31059.1 - 5.9e-15 55.4 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CDS31059.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDS31059.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Exo_endo_phos_2 PF14529.6 CDS31060.1 - 1.1e-10 41.3 0.6 1.7e-10 40.8 0.6 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CDS31061.1 - 6.4e-05 22.6 1.2 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDS31062.1 - 0.0005 20.3 0.0 0.00076 19.7 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDS31062.1 - 0.067 13.9 1.5 0.42 11.4 0.3 2.5 2 1 0 3 3 3 0 zinc-binding in reverse transcriptase C2 PF00168.30 CDS31063.1 - 3e-28 98.1 0.0 1.7e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 CDS31063.1 - 2.8e-18 66.2 14.5 6e-18 65.2 14.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 CDS31063.1 - 0.17 11.6 11.5 0.12 12.1 9.5 1.7 1 1 0 1 1 1 0 Cd27 binding protein (Siva) FYVE PF01363.21 CDS31063.1 - 0.21 11.7 14.6 0.72 10.0 14.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger PPTA PF01239.22 CDS31064.1 - 1.9e-33 113.2 18.0 7.7e-11 41.4 1.0 5.0 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Retrotran_gag_3 PF14244.6 CDS31064.1 - 0.54 10.1 3.3 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Ribosomal_S2 PF00318.20 CDS31065.1 - 3.1e-44 150.8 0.2 5.2e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Arf PF00025.21 CDS31066.1 - 3.8e-49 166.5 0.0 4.9e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CDS31066.1 - 5.3e-14 52.1 0.0 6.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS31066.1 - 2.4e-10 40.6 0.0 3.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDS31066.1 - 1.4e-07 31.0 0.0 6.5e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDS31066.1 - 3.7e-06 26.5 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDS31066.1 - 0.0001 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS31066.1 - 0.00099 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDS31066.1 - 0.24 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase KH_1 PF00013.29 CDS31067.1 - 3.5e-47 158.1 11.8 3.1e-16 58.9 0.3 3.4 3 0 0 3 3 3 3 KH domain DUF1897 PF09005.10 CDS31067.1 - 2.6e-17 62.0 4.5 8.6e-17 60.3 4.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) KH_2 PF07650.17 CDS31067.1 - 1.4e-12 47.2 3.7 0.00064 19.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDS31067.1 - 1.6e-09 37.5 0.9 0.052 13.4 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CDS31067.1 - 0.044 13.9 2.9 6.4 6.9 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain 40S_S4_C PF16121.5 CDS31067.1 - 0.11 12.2 2.2 3.9 7.2 0.1 2.9 3 0 0 3 3 3 0 40S ribosomal protein S4 C-terminus GATA PF00320.27 CDS31068.1 - 2.9e-15 55.6 3.2 5.8e-15 54.6 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CDS31068.1 - 0.011 15.2 0.5 0.02 14.4 0.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CDS31068.1 - 0.018 15.1 0.2 0.04 14.0 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Myb_DNA-bind_6 PF13921.6 CDS31069.1 - 0.043 14.1 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Forkhead PF00250.18 CDS31070.1 - 2e-37 127.3 0.2 7.7e-37 125.4 0.0 2.0 1 1 1 2 2 2 1 Forkhead domain FHA PF00498.26 CDS31070.1 - 0.003 17.9 0.2 0.012 16.0 0.2 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDS31070.1 - 0.038 14.3 0.0 0.099 13.0 0.0 1.8 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain MSP7_C PF12948.7 CDS31071.1 - 0.18 12.5 6.3 0.11 13.1 0.7 2.6 3 0 0 3 3 3 0 MSP7-like protein C-terminal domain FHA PF00498.26 CDS31072.1 - 2.4e-13 50.2 0.1 3.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 FHA domain HTH_48 PF17906.1 CDS31073.1 - 1.4e-07 31.5 0.4 2e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF763 PF05559.11 CDS31073.1 - 0.12 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Btz PF09405.10 CDS31074.1 - 0.82 9.9 6.4 0.11 12.8 0.7 2.4 2 1 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding NKAP PF15692.5 CDS31074.1 - 2.6 8.8 22.9 0.62 10.8 13.6 3.2 1 1 1 2 2 2 0 NF-kappa-B-activating protein REV PF00424.18 CDS31074.1 - 7 6.8 8.9 4.2 7.4 1.2 2.6 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Acid_PPase PF12689.7 CDS31075.1 - 1.5e-40 138.8 0.0 1.7e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 CDS31075.1 - 3.2e-06 27.3 0.0 2.1e-05 24.7 0.0 1.9 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Birna_RdRp PF04197.12 CDS31075.1 - 0.014 13.7 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Hydrolase PF00702.26 CDS31075.1 - 0.03 14.6 0.0 0.25 11.6 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 CDS31076.1 - 5.2e-39 133.8 0.0 6.1e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 CDS31076.1 - 0.00049 20.2 0.3 0.0017 18.5 0.0 1.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA PF00004.29 CDS31080.2 - 3.4e-39 134.3 0.1 2e-38 131.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CDS31080.2 - 2e-33 115.9 0.0 3.2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CDS31080.2 - 5.8e-09 35.6 0.2 6e-08 32.4 0.0 2.7 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 CDS31080.2 - 1.9e-06 27.9 0.1 3.7e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS31080.2 - 2.7e-05 24.6 1.3 0.00015 22.2 0.5 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDS31080.2 - 3e-05 24.3 0.0 0.043 14.1 0.0 3.6 1 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CDS31080.2 - 0.00052 19.8 0.0 0.0022 17.8 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDS31080.2 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CDS31080.2 - 0.0039 17.6 0.0 0.014 15.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 CDS31080.2 - 0.0082 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDS31080.2 - 0.009 15.8 0.4 0.055 13.2 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDS31080.2 - 0.014 15.4 0.0 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CDS31080.2 - 0.059 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain CARD PF00619.21 CDS31080.2 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Caspase recruitment domain AAA_30 PF13604.6 CDS31080.2 - 0.065 13.0 0.2 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsH_ext PF06480.15 CDS31080.2 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 FtsH Extracellular DUF815 PF05673.13 CDS31080.2 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CDS31080.2 - 0.11 11.8 0.2 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Noc2 PF03715.13 CDS31082.2 - 3.7e-31 108.5 1.4 2.8e-23 82.6 0.4 2.2 2 0 0 2 2 2 2 Noc2p family FHA PF00498.26 CDS31082.2 - 2.3e-11 43.9 0.1 6.6e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 FHA domain PAS_2 PF08446.11 CDS31082.2 - 0.17 12.6 0.2 0.56 10.9 0.1 1.9 2 0 0 2 2 2 0 PAS fold HEAT_2 PF13646.6 CDS31083.1 - 2.7e-07 30.9 1.6 0.017 15.5 0.3 2.8 1 1 1 2 2 2 2 HEAT repeats Pkinase_Tyr PF07714.17 CDS31083.1 - 3.6e-07 29.7 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 CDS31083.1 - 4.5e-06 26.5 3.8 0.049 13.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 CDS31083.1 - 0.00016 21.8 0.0 0.0045 17.0 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 CDS31083.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HEAT_EZ PF13513.6 CDS31083.1 - 0.035 14.6 1.9 4.2 8.0 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.20 CDS31083.1 - 0.041 12.4 0.0 0.88 8.1 0.0 2.2 1 1 1 2 2 2 0 Adaptin N terminal region UQ_con PF00179.26 CDS31085.2 - 6.5e-48 161.9 0.0 7.4e-48 161.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS31085.2 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CDS31085.2 - 0.029 14.7 0.0 0.032 14.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 CDS31085.2 - 0.037 13.9 0.1 0.071 13.0 0.1 1.5 1 1 1 2 2 2 0 UEV domain DUF4514 PF14986.6 CDS31086.2 - 0.014 15.4 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) zf-CSL PF05207.13 CDS31086.2 - 0.72 9.6 4.3 0.39 10.5 2.0 1.7 2 0 0 2 2 2 0 CSL zinc finger EF-hand_7 PF13499.6 CDS31087.2 - 3.1e-09 37.2 0.1 0.0067 16.9 0.0 4.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS31087.2 - 0.0016 18.2 0.0 6.9 6.9 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CDS31087.2 - 0.011 15.3 0.0 3.4 7.4 0.0 3.7 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 CDS31089.2 - 3.1e-08 33.9 6.1 0.0042 17.5 0.2 4.9 4 1 2 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS31089.2 - 0.0011 18.7 7.9 0.28 11.2 0.0 5.3 5 1 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 CDS31089.2 - 0.0012 18.6 0.3 5.2 7.0 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS31089.2 - 0.0013 19.1 0.5 0.015 15.6 0.0 2.8 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CDS31089.2 - 0.0068 15.9 0.4 0.0068 15.9 0.4 2.6 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 CDS31089.2 - 0.019 14.5 6.5 0.024 14.2 0.1 4.2 6 0 0 6 6 6 0 EF hand Cadherin PF00028.17 CDS31091.2 - 2.9e-52 175.1 0.6 8.1e-17 61.5 0.0 7.2 6 1 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CDS31091.2 - 0.0019 18.0 0.3 0.76 9.7 0.1 4.4 6 0 0 6 6 6 1 Cadherin-like He_PIG PF05345.12 CDS31091.2 - 0.054 13.7 0.0 0.45 10.8 0.0 2.7 2 0 0 2 2 2 0 Putative Ig domain Cadherin_4 PF17803.1 CDS31091.2 - 0.35 11.5 16.1 0.68 10.6 1.1 5.4 5 0 0 5 5 5 0 Bacterial cadherin-like domain MA3 PF02847.17 CDS31092.2 - 5.2e-12 45.8 0.1 4e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 MA3 domain PI3K_P85_iSH2 PF16454.5 CDS31095.1 - 0.0088 15.6 2.9 0.0088 15.6 2.9 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prominin PF05478.11 CDS31095.1 - 0.19 9.7 1.7 0.35 8.8 1.7 1.3 1 0 0 1 1 1 0 Prominin Sec23_trunk PF04811.15 CDS31096.2 - 3.2e-63 213.5 0.0 4.6e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDS31096.2 - 2.7e-27 94.6 0.1 7.1e-27 93.2 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CDS31096.2 - 1.3e-26 93.1 0.6 3.1e-26 91.9 0.6 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDS31096.2 - 5.4e-13 48.7 12.7 1.4e-12 47.4 12.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDS31096.2 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MA3 PF02847.17 CDS31098.1 - 2.2e-06 27.6 0.1 0.037 14.0 0.0 2.4 2 0 0 2 2 2 2 MA3 domain MIF4G PF02854.19 CDS31100.2 - 1.9e-16 60.4 5.1 3e-16 59.7 5.1 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 CDS31100.2 - 3e-13 49.7 0.8 6.1e-09 35.9 0.1 3.0 3 0 0 3 3 3 2 MA3 domain zf-C2H2 PF00096.26 CDS31101.2 - 3.9e-11 42.7 34.9 0.0031 17.9 1.5 5.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31101.2 - 7.4e-10 38.8 31.6 0.024 15.4 0.7 6.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS31101.2 - 1.9e-08 34.1 27.2 0.00073 19.5 6.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger ELM2 PF01448.24 CDS31101.2 - 7.9e-08 32.9 0.0 2.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain zf-C2H2_jaz PF12171.8 CDS31101.2 - 3.6e-05 23.9 18.0 0.36 11.2 0.2 5.1 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CDS31101.2 - 0.027 14.3 1.2 0.096 12.5 1.2 2.0 1 0 0 1 1 1 0 GAGA factor zf-C2H2_2 PF12756.7 CDS31101.2 - 0.035 14.4 14.5 2.7 8.4 0.0 4.3 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDS31101.2 - 0.16 12.4 22.5 0.81 10.2 0.2 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Cofilin_ADF PF00241.20 CDS31102.2 - 3e-28 98.0 0.1 3.3e-28 97.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 CDS31103.1 - 1.8e-33 114.9 0.3 2e-33 114.7 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2540 PF10802.8 CDS31103.1 - 0.011 15.8 0.3 0.019 15.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DUF4363 PF14276.6 CDS31103.1 - 0.07 13.3 1.2 1.6 8.9 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4363) LAP1C PF05609.12 CDS31104.2 - 0.027 13.6 0.0 0.2 10.7 0.0 2.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AAA_9 PF12781.7 CDS31106.2 - 0.085 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 ATP-binding dynein motor region DUF2487 PF10673.9 CDS31106.2 - 0.14 12.2 0.2 4.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2487) Integrin_beta PF00362.18 CDS31107.1 - 1.5e-89 299.9 0.0 2.2e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Integrin beta chain VWA domain Integrin_b_cyt PF08725.11 CDS31107.1 - 2.7e-17 62.1 0.4 5.2e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.13 CDS31107.1 - 2.9e-13 49.9 73.1 9.2e-06 25.9 11.1 5.3 5 0 0 5 5 5 4 EGF-like domain I-EGF_1 PF18372.1 CDS31107.1 - 6.6e-09 35.7 55.8 4.2e-07 29.9 3.9 5.7 4 1 0 4 4 4 3 Integrin beta epidermal growth factor like domain 1 VWA PF00092.28 CDS31107.1 - 0.011 16.0 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Pkinase PF00069.25 CDS31108.2 - 2.1e-64 217.4 0.0 3.1e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31108.2 - 6.6e-29 101.0 0.0 1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31108.2 - 3.1e-07 30.0 1.1 0.0001 21.7 0.2 2.2 1 1 1 2 2 2 2 Kinase-like HYLS1_C PF15311.6 CDS31108.2 - 0.00043 21.0 2.0 0.00049 20.8 0.2 2.0 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus RIO1 PF01163.22 CDS31108.2 - 0.0011 18.6 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CDS31108.2 - 0.16 10.7 1.6 0.35 9.6 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CDS31108.2 - 0.28 10.5 1.2 3 7.1 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 CDS31110.1 - 1.2e-12 47.9 7.0 1.2e-07 31.8 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31110.1 - 8.9e-05 23.0 1.6 9.9 7.3 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31110.1 - 0.00018 21.3 0.4 12 6.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS31110.1 - 0.0003 20.7 2.8 12 6.3 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS31110.1 - 0.0072 16.8 11.4 4.5 7.9 0.1 5.0 3 2 3 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 CDS31110.1 - 0.01 15.9 1.7 0.21 11.7 0.7 3.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 CDS31110.1 - 0.019 15.6 2.0 91 4.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDS31110.1 - 0.45 9.7 0.0 0.45 9.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 CDS31110.1 - 1.5 8.7 6.8 0.4 10.6 0.2 3.0 4 0 0 4 4 4 0 YfdX protein Nucleoporin_C PF03177.14 CDS31111.1 - 3.3e-11 42.7 0.2 4.9e-10 38.8 0.2 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal S-layer PF07752.11 CDS31111.1 - 0.024 13.7 0.4 0.042 12.9 0.4 1.3 1 0 0 1 1 1 0 S-layer protein Pkinase PF00069.25 CDS31112.1 - 6.2e-58 196.2 0.5 1.6e-23 83.4 0.0 4.3 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31112.1 - 3.7e-32 111.6 0.0 3.6e-15 55.9 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase APH PF01636.23 CDS31112.1 - 2e-05 24.6 0.1 0.008 16.1 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS31112.1 - 0.00043 19.3 0.5 0.71 8.8 0.1 2.3 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 CDS31112.1 - 0.0022 17.4 0.4 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS31112.1 - 0.0099 15.2 0.0 0.11 11.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like RWD PF05773.22 CDS31112.1 - 0.011 16.1 0.4 0.04 14.2 0.4 2.0 1 0 0 1 1 1 0 RWD domain ASD1 PF08688.10 CDS31112.1 - 0.013 15.9 0.7 0.044 14.2 0.7 1.9 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 PAZ PF02170.22 CDS31112.1 - 0.016 15.0 0.3 0.052 13.4 0.1 1.9 2 0 0 2 2 2 0 PAZ domain FTA2 PF13095.6 CDS31112.1 - 0.098 12.3 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWIM PF04434.17 CDS31113.2 - 0.15 11.7 3.1 6 6.6 0.3 2.6 2 0 0 2 2 2 0 SWIM zinc finger DUF2070 PF09843.9 CDS31113.2 - 0.59 8.4 3.1 0.67 8.2 3.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Innexin PF00876.18 CDS31114.1 - 1.9e-120 402.4 8.8 8e-68 229.3 2.7 2.0 2 0 0 2 2 2 2 Innexin Synaptobrevin PF00957.21 CDS31115.1 - 1.5e-30 104.8 0.4 1.9e-30 104.5 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 CDS31115.1 - 0.056 13.5 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Reticulon PF02453.17 CDS31115.1 - 0.076 13.0 0.1 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Reticulon FHA PF00498.26 CDS31116.1 - 1.6e-11 44.4 0.4 2.4e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDS31116.1 - 0.0019 18.5 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RPAP1_C PF08620.10 CDS31117.1 - 1.2e-22 79.8 0.1 2.7e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CDS31117.1 - 2e-10 40.3 1.7 6.1e-10 38.7 1.7 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal zf-C2H2 PF00096.26 CDS31119.1 - 9.3e-10 38.4 24.3 0.0047 17.3 4.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31119.1 - 6.8e-08 32.7 20.7 0.0078 17.0 2.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS31119.1 - 1e-06 28.9 17.8 0.00035 20.9 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS31119.1 - 6.8e-05 23.0 9.6 0.23 11.8 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS31119.1 - 0.0011 18.9 16.8 0.023 14.7 1.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CDS31119.1 - 0.013 15.9 9.9 0.94 10.0 1.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 CDS31119.1 - 0.066 13.3 5.2 18 5.6 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 CDS31119.1 - 0.28 11.6 9.4 1.5 9.3 1.5 3.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 CDS31119.1 - 0.33 11.2 4.0 5.9 7.2 3.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-Di19 PF05605.12 CDS31119.1 - 0.34 11.2 7.5 6.4 7.2 2.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 CDS31119.1 - 0.4 10.9 12.0 0.53 10.5 1.9 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 CDS31119.1 - 0.81 9.7 16.8 1.1 9.2 1.9 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CRD PF17979.1 CDS31119.1 - 0.83 9.7 9.1 2 8.5 4.5 2.3 1 1 2 3 3 3 0 Cysteine rich domain with multizinc binding regions zf-C2H2_2 PF12756.7 CDS31119.1 - 1.9 8.9 9.1 5.2 7.5 1.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 CDS31119.1 - 5.2 7.4 8.5 7.3 6.9 0.1 3.0 1 1 2 3 3 3 0 zinc-ribbon zf_C2H2_ZHX PF18387.1 CDS31119.1 - 7.9 6.2 9.5 35 4.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Nucleic_acid_bd PF13820.6 CDS31120.1 - 0.0032 17.3 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative nucleic acid-binding region DDOST_48kD PF03345.14 CDS31121.1 - 9.1e-144 479.3 0.6 1.1e-143 479.1 0.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 CDS31121.1 - 0.00015 22.2 0.0 0.32 11.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4350) AMPK1_CBM PF16561.5 CDS31123.1 - 2e-32 111.2 0.2 3.1e-32 110.6 0.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CDS31123.1 - 2e-22 79.3 1.8 2.9e-22 78.7 0.6 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 CDS31123.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PI3_PI4_kinase PF00454.27 CDS31124.1 - 2.2e-51 175.1 0.2 5.6e-51 173.8 0.2 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDS31124.1 - 3.1e-28 98.5 0.1 1.1e-16 60.8 0.0 2.8 3 0 0 3 3 3 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CDS31124.1 - 3.6e-21 75.5 0.0 7.9e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_p85B PF02192.16 CDS31124.1 - 7.2e-21 73.7 0.1 1.8e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.18 CDS31124.1 - 1.5e-10 41.2 0.1 3.6e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 CDS31124.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Pkinase_Tyr PF07714.17 CDS31125.1 - 2.8e-94 315.2 0.0 4.4e-94 314.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS31125.1 - 6.8e-46 156.8 0.0 1.1e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS31125.1 - 4.7e-22 77.9 0.1 1.3e-21 76.5 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDS31125.1 - 9.8e-06 25.1 0.8 5.9e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDS31125.1 - 0.00097 18.9 1.7 0.084 12.7 1.7 2.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS31125.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 CDS31125.1 - 0.018 15.0 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS31125.1 - 0.034 13.1 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain B2 PF11473.8 CDS31125.1 - 0.18 11.6 0.3 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding protein B2 Laminin_G_3 PF13385.6 CDS31126.1 - 1.4e-21 77.2 21.3 5e-06 26.7 1.0 5.6 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.21 CDS31126.1 - 6.4e-11 42.6 4.4 2.5e-10 40.7 4.4 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 CDS31126.1 - 1.1 8.4 20.0 2 7.7 20.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) eIF-1a PF01176.19 CDS31127.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-C2H2 PF00096.26 CDS31128.1 - 4.4e-17 61.5 20.9 0.00034 20.9 0.2 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31128.1 - 1.9e-12 47.0 24.2 3.1e-06 27.4 0.2 5.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31128.1 - 1.8e-09 37.6 24.0 0.027 15.3 0.3 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger Raffinose_syn PF05691.12 CDS31128.1 - 0.19 9.5 0.3 0.43 8.3 0.0 1.6 2 0 0 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 zf-C2H2_aberr PF17017.5 CDS31128.1 - 0.21 11.7 3.4 44 4.1 0.0 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger IBR PF01485.21 CDS31128.1 - 0.67 10.2 7.5 0.53 10.6 1.0 2.9 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 CDS31128.1 - 0.68 10.0 12.9 8 6.6 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS31128.1 - 1.1 9.1 5.3 14 5.5 0.3 3.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CDS31128.1 - 3.2 8.2 5.5 64 4.0 0.1 4.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 CDS31128.1 - 5.4 7.8 9.4 23 5.8 2.9 3.7 2 1 3 5 5 5 0 TRAF-type zinc finger ASC PF00858.24 CDS31130.1 - 8.7e-59 199.6 0.1 5.3e-58 197.0 0.1 1.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel NAD_synthase PF02540.17 CDS31131.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 NAD synthase CAP_GLY PF01302.25 CDS31132.1 - 8e-23 80.2 1.9 1.2e-22 79.7 1.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CDS31132.1 - 2.2e-20 72.9 0.2 5.9e-20 71.5 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain tRNA-synt_1 PF00133.22 CDS31133.1 - 2.5e-193 643.6 0.0 2.3e-192 640.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDS31133.1 - 4.5e-30 104.6 0.0 1.6e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDS31133.1 - 1.4e-10 40.5 0.2 9.7e-06 24.6 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDS31133.1 - 2.4e-10 40.2 0.0 1.3e-07 31.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 DOCK_N PF16172.5 CDS31133.1 - 0.035 13.0 0.0 2.4 7.0 0.1 2.2 2 0 0 2 2 2 0 DOCK N-terminus tRNA-synt_1e PF01406.19 CDS31133.1 - 0.047 13.0 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain EGF PF00008.27 CDS31134.1 - 2.9e-21 75.4 134.8 4.1e-07 30.2 5.2 10.7 10 1 0 10 10 10 7 EGF-like domain DSL PF01414.19 CDS31134.1 - 2.7e-17 62.8 1.2 2.7e-17 62.8 1.2 7.4 6 1 1 7 7 7 3 Delta serrate ligand hEGF PF12661.7 CDS31134.1 - 1.4e-13 50.9 98.5 5.8e-06 26.7 3.0 11.2 11 0 0 11 11 11 6 Human growth factor-like EGF EGF_2 PF07974.13 CDS31134.1 - 9.2e-11 41.9 135.6 0.0037 17.6 11.3 9.9 9 0 0 9 9 9 7 EGF-like domain EGF_CA PF07645.15 CDS31134.1 - 2.2e-05 24.6 4.7 2.2e-05 24.6 4.7 10.7 4 3 7 11 11 11 2 Calcium-binding EGF domain Laminin_EGF PF00053.24 CDS31134.1 - 0.019 15.1 114.2 2.8 8.2 5.2 9.9 2 2 7 9 9 9 0 Laminin EGF domain DUF3810 PF12725.7 CDS31134.1 - 0.27 10.6 0.6 0.41 9.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) IRF-2BP1_2 PF11261.8 CDS31135.1 - 1.6e-30 104.4 3.2 4e-29 99.9 0.8 2.8 3 0 0 3 3 3 1 Interferon regulatory factor 2-binding protein zinc finger BIR PF00653.21 CDS31135.1 - 0.042 14.5 0.8 2.7 8.7 0.4 2.8 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C3HC4 PF00097.25 CDS31135.1 - 0.057 13.3 2.2 0.26 11.2 2.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS31135.1 - 0.087 12.7 2.9 0.27 11.1 2.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nudix_N_2 PF14803.6 CDS31135.1 - 1.7 8.6 5.8 4.4 7.3 0.0 3.8 4 0 0 4 4 4 0 Nudix N-terminal zf-CCHC_4 PF14392.6 CDS31135.1 - 5.1 6.9 8.1 4.3 7.1 0.0 3.7 4 0 0 4 4 4 0 Zinc knuckle Hist_deacetyl PF00850.19 CDS31136.1 - 4.4e-65 220.2 0.1 1.6e-44 152.6 0.0 2.1 2 0 0 2 2 2 2 Histone deacetylase domain Lantibiotic_a PF14867.6 CDS31136.1 - 0.072 12.8 0.7 0.46 10.3 0.4 2.3 2 0 0 2 2 2 0 Lantibiotic alpha eIF2A PF08662.11 CDS31138.1 - 7.8e-54 182.5 0.0 1e-52 178.9 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RAMA PF18755.1 CDS31138.1 - 0.086 13.3 1.0 0.86 10.0 0.1 2.6 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated WD40 PF00400.32 CDS31138.1 - 0.1 13.5 0.4 1.9 9.5 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat PIG-P PF08510.12 CDS31139.1 - 1.1e-26 93.2 1.2 1.4e-26 92.8 1.2 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CDS31139.1 - 0.022 15.0 11.3 0.049 13.9 11.3 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.11 CDS31139.1 - 0.32 11.1 1.6 0.47 10.5 1.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III UPF0242 PF06785.11 CDS31139.1 - 0.44 10.6 1.4 0.53 10.4 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Taeniidae_ag PF05596.11 CDS31140.1 - 1e-15 57.4 0.4 1.2e-15 57.2 0.4 1.1 1 0 0 1 1 1 1 Taeniidae antigen Apolipoprotein PF01442.18 CDS31140.1 - 0.0062 16.4 0.1 0.0072 16.2 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain UPF0139 PF03669.13 CDS31140.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Taeniidae_ag PF05596.11 CDS31141.1 - 3.3e-13 49.4 0.3 5.3e-13 48.7 0.3 1.4 1 1 0 1 1 1 1 Taeniidae antigen DUF615 PF04751.14 CDS31141.1 - 0.026 14.5 0.1 0.029 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Mt_ATP-synt_D PF05873.12 CDS31141.1 - 0.092 12.6 0.1 0.099 12.5 0.1 1.0 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Taeniidae_ag PF05596.11 CDS31142.1 - 1.9e-12 47.0 0.3 2.1e-12 46.8 0.3 1.1 1 0 0 1 1 1 1 Taeniidae antigen THP2 PF09432.10 CDS31142.1 - 0.078 13.0 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 RsdA_SigD_bd PF16751.5 CDS31142.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region DUF3860 PF12976.7 CDS31142.1 - 0.19 11.7 3.8 1.9 8.6 0.1 2.4 1 1 2 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) FHA PF00498.26 CDS31143.1 - 3.5e-10 40.1 0.5 6.8e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 FHA domain SMC_N PF02463.19 CDS31144.1 - 1.2e-75 253.7 0.0 2.1e-75 252.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDS31144.1 - 6.7e-21 74.8 0.3 6.6e-20 71.6 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDS31144.1 - 9.6e-14 51.9 3.5 1.2e-07 31.8 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDS31144.1 - 3.1e-13 50.7 10.0 3.1e-13 50.7 10.0 6.8 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.6 CDS31144.1 - 8.4e-11 42.2 3.8 8.4e-11 42.2 3.8 3.0 2 1 0 2 2 2 1 AAA ATPase domain ATG16 PF08614.11 CDS31144.1 - 3.9e-07 30.5 39.3 7.1e-05 23.1 10.2 7.6 3 2 5 8 8 7 2 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 CDS31144.1 - 1.4e-05 24.6 47.6 1.4e-05 24.6 47.6 5.7 2 2 3 6 6 4 1 Tropomyosin AAA_29 PF13555.6 CDS31144.1 - 3e-05 23.7 0.0 8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Uso1_p115_C PF04871.13 CDS31144.1 - 0.00062 20.1 13.3 0.00062 20.1 13.3 8.3 2 2 5 7 7 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 CDS31144.1 - 0.0075 16.3 10.2 0.0075 16.3 10.2 7.3 3 2 3 7 7 7 2 Laminin Domain II ABC_tran PF00005.27 CDS31144.1 - 1.1 9.7 0.0 1.1 9.7 0.0 6.6 4 2 1 6 6 6 0 ABC transporter DUF5405 PF17399.2 CDS31144.1 - 1.4 9.2 6.0 12 6.3 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5405) Spc7 PF08317.11 CDS31144.1 - 2.1 7.2 124.1 0.045 12.6 10.2 7.3 3 2 3 7 7 7 0 Spc7 kinetochore protein AAA_22 PF13401.6 CDS31144.1 - 2.5 8.4 0.0 2.5 8.4 0.0 4.6 5 1 0 5 5 5 0 AAA domain 4F5 PF04419.14 CDS31145.1 - 1.7e-06 28.8 6.8 2.8e-06 28.1 6.8 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 CDS31145.1 - 2.6e-05 24.4 0.4 5.7e-05 23.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS31145.1 - 0.0032 17.7 0.6 0.0062 16.8 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CDS31145.1 - 0.029 12.9 0.6 0.043 12.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 CDS31145.1 - 0.032 15.1 0.6 0.047 14.5 0.6 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf_UBZ PF18439.1 CDS31145.1 - 0.061 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-met2 PF12907.7 CDS31145.1 - 0.91 9.7 5.4 7.2 6.8 5.4 2.2 1 1 0 1 1 1 0 Zinc-binding DLH PF01738.18 CDS31146.1 - 2.7e-09 36.9 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 CDS31146.1 - 0.00013 20.7 0.0 0.00015 20.4 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 CDS31146.1 - 0.073 12.7 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) tRNA-synt_1c PF00749.21 CDS31147.1 - 9.9e-104 346.6 0.0 9.9e-104 346.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDS31147.1 - 2.2e-27 96.0 0.1 9.7e-27 93.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ProRS-C_1 PF09180.11 CDS31147.1 - 3.3e-19 68.8 0.1 1e-18 67.3 0.1 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CDS31147.1 - 1.5e-15 57.6 0.0 5.9e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDS31147.1 - 5.2e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain GST_C_3 PF14497.6 CDS31147.1 - 8.3e-05 22.7 0.0 0.00035 20.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDS31147.1 - 0.00018 21.4 0.0 0.00061 19.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 CDS31147.1 - 0.064 12.6 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.25 CDS31147.1 - 0.19 12.0 1.9 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 CDS31148.1 - 1.5e-57 194.0 0.0 5.7e-32 111.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDS31148.1 - 5e-37 127.8 54.6 1.2e-20 73.9 27.4 3.9 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDS31148.1 - 3.5e-21 76.3 1.0 4.8e-08 33.2 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDS31148.1 - 4.3e-07 30.6 1.4 0.0064 17.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF4162 PF13732.6 CDS31148.1 - 3.9e-05 24.3 0.0 0.00091 19.9 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 CDS31148.1 - 0.00039 19.9 0.3 0.1 12.1 0.0 3.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 CDS31148.1 - 0.00077 19.1 1.3 0.76 9.4 0.3 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CDS31148.1 - 0.0014 18.6 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CDS31148.1 - 0.0059 17.0 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDS31148.1 - 0.0071 16.1 0.6 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CDS31148.1 - 0.038 13.3 0.0 12 5.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CDS31148.1 - 0.039 13.7 0.4 8.7 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CDS31148.1 - 0.055 13.7 0.0 1.8 8.9 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 CDS31148.1 - 0.06 13.2 1.1 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 CDS31148.1 - 0.08 13.0 0.1 29 4.8 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 CDS31148.1 - 0.35 10.5 7.8 1.5 8.4 0.0 4.6 7 0 0 7 7 7 0 AAA ATPase domain NIF PF03031.18 CDS31149.1 - 1e-49 168.3 0.0 1.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Smim3 PF17307.2 CDS31150.1 - 0.063 12.8 0.2 0.086 12.3 0.2 1.2 1 0 0 1 1 1 0 Small integral membrane protein 3 Dpy-30 PF05186.13 CDS31151.1 - 1.6e-07 30.9 0.5 4.8e-07 29.4 0.5 1.9 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CDS31151.1 - 4.1e-07 30.2 0.2 7e-05 23.0 0.1 2.9 3 1 0 3 3 3 1 Adenylate kinase AAA_17 PF13207.6 CDS31151.1 - 4.1e-06 27.3 3.0 0.034 14.6 0.0 4.0 3 1 1 4 4 4 2 AAA domain Hydin_ADK PF17213.3 CDS31151.1 - 1.2e-05 25.7 0.1 5.8e-05 23.5 0.1 1.9 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDS31151.1 - 2.4e-05 24.9 3.6 0.026 15.1 0.0 4.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDS31151.1 - 0.01 16.3 0.1 0.53 10.7 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RIG-I_C PF18119.1 CDS31151.1 - 0.048 13.7 0.0 0.2 11.7 0.0 2.1 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain AAA_25 PF13481.6 CDS31151.1 - 0.06 12.9 0.0 1.7 8.1 0.0 3.1 3 1 0 3 3 3 0 AAA domain RIIa PF02197.17 CDS31151.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit AAA_28 PF13521.6 CDS31151.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDS31151.1 - 3.1 8.0 4.6 12 6.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain bZIP_2 PF07716.15 CDS31152.1 - 1.8 8.7 6.7 1.4 9.1 3.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper ATP-grasp_2 PF08442.10 CDS31153.1 - 4.6e-67 225.5 0.7 4.6e-67 225.5 0.7 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDS31153.1 - 5.6e-27 94.4 2.3 1.4e-26 93.1 2.3 1.7 1 0 0 1 1 1 1 CoA-ligase GARS_A PF01071.19 CDS31153.1 - 0.00034 20.5 0.8 0.0015 18.4 0.8 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 CDS31153.1 - 0.00037 20.0 0.4 0.0016 17.9 0.4 2.2 1 1 0 1 1 1 1 ATP-grasp domain nsp7 PF08716.10 CDS31153.1 - 0.099 13.3 0.2 0.86 10.3 0.3 2.3 2 0 0 2 2 2 0 nsp7 replicase OKR_DC_1_N PF03709.15 CDS31153.1 - 0.13 12.5 0.3 1.7 9.0 0.0 2.2 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain SNF2_N PF00176.23 CDS31154.1 - 1e-65 221.7 0.0 3.7e-65 220.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CDS31154.1 - 1.3e-20 74.1 18.9 3.2e-17 63.1 3.5 3.2 3 0 0 3 3 3 2 DNA-binding domain Helicase_C PF00271.31 CDS31154.1 - 2.5e-16 60.0 0.1 2.8e-15 56.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31154.1 - 4.7e-07 30.0 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDS31154.1 - 5.8e-05 22.4 0.0 0.00067 18.9 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_33 PF13671.6 CDS31154.1 - 0.2 11.8 4.1 0.099 12.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain RrnaAD PF00398.20 CDS31155.1 - 6.1e-59 199.3 0.0 7.4e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CDS31155.1 - 5e-08 33.5 0.0 9.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS31155.1 - 2.7e-05 24.8 0.0 5.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS31155.1 - 2.9e-05 23.9 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS31155.1 - 6.5e-05 23.5 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS31155.1 - 0.00027 20.5 0.0 0.00066 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDS31155.1 - 0.00052 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDS31155.1 - 0.00073 19.3 0.0 0.0018 18.1 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 CDS31155.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 CDS31155.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 CDS31155.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase UPF0020 PF01170.18 CDS31155.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 CDS31155.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 CDS31155.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CDS31155.1 - 0.043 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 CDS31155.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 CDS31155.1 - 0.076 12.5 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 CDS31155.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.6 CDS31155.1 - 0.16 12.8 0.0 0.28 12.0 0.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Kinesin PF00225.23 CDS31157.1 - 1.3e-108 362.8 0.0 2.7e-108 361.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CDS31157.1 - 4.2e-38 131.3 12.4 9e-31 107.4 0.6 3.5 3 1 1 4 4 4 2 Kinesin-associated DUF3694 PF12473.8 CDS31157.1 - 3.2e-32 112.3 0.0 8.8e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CDS31157.1 - 6.7e-21 74.8 0.0 2.1e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CDS31157.1 - 0.0003 21.3 0.5 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 CDS31157.1 - 0.015 15.7 0.0 0.015 15.7 0.0 3.0 2 1 0 2 2 2 0 Kinesin protein 1B CLTH PF10607.9 CDS31157.1 - 0.046 13.6 0.2 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Yop-YscD_cpl PF16697.5 CDS31157.1 - 0.089 13.1 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RGS PF00615.19 CDS31160.1 - 2.1e-31 108.7 2.8 3.8e-31 107.8 2.8 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain HTH_32 PF13565.6 CDS31162.1 - 2.5e-06 28.0 0.5 0.018 15.6 0.0 3.3 4 0 0 4 4 4 2 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CDS31162.1 - 0.00079 19.7 1.2 0.0019 18.5 1.2 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 CDS31162.1 - 0.0056 16.8 0.9 0.015 15.4 0.9 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_33 PF13592.6 CDS31162.1 - 0.014 15.0 0.1 0.16 11.6 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix BPL_LplA_LipB PF03099.19 CDS31164.1 - 1.1e-10 41.6 0.5 1.7e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CDS31164.1 - 9.7e-05 22.2 0.1 0.00033 20.5 0.1 1.9 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain zf-C2H2_4 PF13894.6 CDS31165.1 - 0.0045 17.7 0.8 0.0094 16.7 0.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF4764 PF15961.5 CDS31165.1 - 0.006 15.4 6.5 0.029 13.1 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4764) zf-C2H2 PF00096.26 CDS31165.1 - 0.022 15.2 0.8 0.044 14.3 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 CDS31165.1 - 0.026 14.9 1.8 1.4 9.4 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RBR PF17208.3 CDS31165.1 - 0.044 14.5 0.3 0.044 14.5 0.3 2.1 2 0 0 2 2 2 0 RNA binding Region BolA PF01722.18 CDS31165.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 BolA-like protein zf-C2HC_2 PF13913.6 CDS31165.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PPI_Ypi1 PF07491.11 CDS31166.1 - 6.5e-19 67.5 0.2 6.5e-19 67.5 0.2 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor NMD3 PF04981.13 CDS31167.1 - 1.2e-62 211.5 4.0 1.7e-62 211.1 4.0 1.2 1 0 0 1 1 1 1 NMD3 family Ax_dynein_light PF10211.9 CDS31168.1 - 3e-90 301.2 13.4 3.4e-90 301.0 13.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain RIB43A PF05914.12 CDS31168.1 - 0.098 11.4 12.6 0.2 10.3 12.7 1.5 1 1 0 1 1 1 0 RIB43A PRKG1_interact PF15898.5 CDS31168.1 - 0.2 12.5 9.6 0.12 13.3 6.5 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TSNAXIP1_N PF15739.5 CDS31168.1 - 0.53 10.7 11.7 0.17 12.3 2.3 2.5 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF724 PF05266.14 CDS31168.1 - 0.6 9.9 8.3 0.73 9.6 7.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Scramblase PF03803.15 CDS31169.1 - 4.9e-32 111.0 1.0 3.5e-31 108.2 1.0 1.9 1 1 0 1 1 1 1 Scramblase DUF608 PF04685.13 CDS31171.1 - 1.2e-128 429.4 4.1 1.6e-128 429.0 4.1 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 CDS31171.1 - 3e-101 339.0 0.0 5e-101 338.3 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ribosomal_S19 PF00203.21 CDS31172.1 - 3.7e-34 116.5 0.3 5.3e-34 115.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_transf_21 PF13506.6 CDS31173.1 - 2.3e-39 134.6 0.0 4.6e-39 133.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CDS31173.1 - 9.8e-13 48.5 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDS31173.1 - 2.4e-12 47.2 4.7 2.4e-12 47.2 4.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Tim44 PF04280.15 CDS31174.1 - 0.00053 20.1 0.0 0.0007 19.7 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain Tim44 PF04280.15 CDS31176.1 - 0.00052 20.1 0.0 0.00076 19.6 0.0 1.2 1 0 0 1 1 1 1 Tim44-like domain WD40 PF00400.32 CDS31177.1 - 1.5e-10 41.5 7.2 0.029 15.2 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDS31177.1 - 0.0081 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein UQ_con PF00179.26 CDS31179.1 - 5.7e-33 113.5 0.0 3.3e-32 111.1 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme FYVE PF01363.21 CDS31179.1 - 0.11 12.7 3.5 0.18 12.0 1.7 2.2 2 0 0 2 2 2 0 FYVE zinc finger Ras PF00071.22 CDS31180.1 - 1.1e-52 177.9 0.0 1.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS31180.1 - 4.9e-19 68.7 0.0 6.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS31180.1 - 2.8e-07 30.1 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CUT PF02376.15 CDS31181.1 - 2e-33 114.4 0.1 7e-22 77.4 0.0 2.7 2 0 0 2 2 2 2 CUT domain Homeodomain PF00046.29 CDS31181.1 - 1.3e-06 28.2 0.0 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Sec34 PF04136.15 CDS31181.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Sec34-like family YdaS_antitoxin PF15943.5 CDS31181.1 - 0.28 11.1 3.1 0.49 10.3 0.0 2.9 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT L_HMGIC_fpl PF10242.9 CDS31182.1 - 3.6e-20 72.9 8.1 1.8e-19 70.7 8.1 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein IF4E PF01652.18 CDS31183.1 - 1.6e-46 158.0 1.4 2e-46 157.7 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2013 PF09431.10 CDS31184.1 - 9.7e-20 71.1 0.3 5.6e-14 52.5 0.0 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF2013) SH3_9 PF14604.6 CDS31184.1 - 4.3e-07 29.7 0.0 8.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS31184.1 - 0.00012 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS31184.1 - 0.00029 20.4 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF3824 PF12868.7 CDS31184.1 - 0.14 12.8 0.9 0.23 12.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DSL PF01414.19 CDS31185.1 - 0.00061 20.0 4.1 0.00061 20.0 4.1 2.9 3 1 1 4 4 4 1 Delta serrate ligand EGF PF00008.27 CDS31185.1 - 0.0074 16.6 4.2 0.0074 16.6 4.2 2.6 2 1 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 CDS31185.1 - 0.07 13.5 14.4 0.065 13.6 7.3 2.9 2 0 0 2 2 2 0 EGF-like domain Insulin_TMD PF17870.1 CDS31185.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment 7tm_1 PF00001.21 CDS31186.1 - 6e-09 35.6 13.4 1e-08 34.8 13.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS31186.1 - 2.5e-08 33.6 18.4 6.3e-06 25.7 9.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srz PF10325.9 CDS31186.1 - 0.0017 17.7 4.8 0.0017 17.7 4.8 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srz Plexin_cytopl PF08337.12 CDS31189.1 - 1.2e-123 413.7 0.0 1.2e-67 228.9 0.0 2.2 2 0 0 2 2 2 2 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CDS31189.1 - 1.8e-17 63.2 1.2 2.5e-10 40.3 0.0 4.7 5 0 0 5 5 5 3 IPT/TIG domain PSI PF01437.25 CDS31189.1 - 1.4e-11 44.7 46.7 3.2e-06 27.6 15.2 3.7 3 0 0 3 3 3 3 Plexin repeat Sema PF01403.19 CDS31189.1 - 2.1e-07 30.1 0.0 5.4e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Sema domain CH PF00307.31 CDS31190.1 - 9.8e-34 115.8 1.6 2.5e-15 56.6 0.0 4.8 4 1 0 4 4 4 2 Calponin homology (CH) domain Spectrin PF00435.21 CDS31190.1 - 1.4e-25 89.8 99.3 5.8e-06 26.7 1.2 16.3 16 3 2 18 18 18 11 Spectrin repeat CAMSAP_CH PF11971.8 CDS31190.1 - 1.6e-09 37.5 0.0 3e-05 23.8 0.0 3.1 2 0 0 2 2 2 2 CAMSAP CH domain PH PF00169.29 CDS31190.1 - 5.7e-05 23.6 0.1 0.00017 22.0 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CDS31190.1 - 0.00064 20.1 0.0 0.0027 18.1 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2524 PF10732.9 CDS31190.1 - 4 7.8 7.1 5.7 7.3 0.5 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) AAA_lid_7 PF17867.1 CDS31190.1 - 5.1 7.4 6.8 6.4 7.0 0.3 4.2 4 0 0 4 4 4 0 Midasin AAA lid domain NUDIX PF00293.28 CDS31191.1 - 2.4e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S3Ae PF01015.18 CDS31192.1 - 0.0093 15.6 0.0 0.012 15.3 0.0 1.2 1 1 0 1 1 1 1 Ribosomal S3Ae family DUF2264 PF10022.9 CDS31192.1 - 0.2 10.7 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Es2 PF09751.9 CDS31193.1 - 3.1e-41 142.5 2.8 3.7e-33 115.9 0.3 2.4 1 1 1 2 2 2 2 Nuclear protein Es2 SHQ1 PF04925.15 CDS31194.1 - 3.6e-47 160.2 0.1 5.4e-47 159.6 0.1 1.3 1 0 0 1 1 1 1 SHQ1 protein RT_RNaseH_2 PF17919.1 CDS31195.1 - 1.7e-19 69.7 0.7 3e-17 62.5 0.7 2.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS31195.1 - 9.5e-19 67.6 0.5 4.3e-17 62.3 0.5 2.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS31195.1 - 3.9e-09 36.4 0.0 9.1e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.23 CDS31196.1 - 8e-50 169.5 0.0 2.8e-49 167.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS31196.1 - 2.2e-12 47.3 0.0 5.8e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31196.1 - 2.5e-06 27.6 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2439 PF10382.9 CDS31196.1 - 5.5e-05 23.4 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) HDA2-3 PF11496.8 CDS31196.1 - 0.00053 19.3 0.0 0.0036 16.5 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CDS31196.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Ribosomal_L1 PF00687.21 CDS31202.1 - 4.7e-45 153.8 2.0 5.9e-45 153.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34e PF01199.18 CDS31202.1 - 0.026 14.8 0.1 0.08 13.3 0.0 1.8 1 1 1 2 2 2 0 Ribosomal protein L34e WD40 PF00400.32 CDS31204.1 - 1.8e-08 34.9 3.2 0.00051 20.8 0.3 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31204.1 - 1.4e-06 28.5 0.0 0.47 10.8 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 CDS31204.1 - 0.0073 14.9 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme WD40_like PF17005.5 CDS31204.1 - 0.0098 15.2 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain Frataxin_Cyay PF01491.16 CDS31205.1 - 1e-32 112.4 0.0 1.4e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain RGS PF00615.19 CDS31207.1 - 2e-32 112.0 1.3 3e-32 111.3 1.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ephrin_rec_like PF07699.13 CDS31208.2 - 0.0001 22.0 8.9 0.0001 22.0 8.9 6.9 5 2 2 7 7 7 3 Putative ephrin-receptor like NCD3G PF07562.14 CDS31208.2 - 0.0016 18.4 36.7 0.11 12.5 7.2 6.0 4 2 1 5 5 5 3 Nine Cysteines Domain of family 3 GPCR cEGF PF12662.7 CDS31208.2 - 8.9 6.3 26.0 0.67 9.9 2.1 5.2 4 0 0 4 4 4 0 Complement Clr-like EGF-like Pkinase PF00069.25 CDS31209.1 - 7.8e-37 127.1 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31209.1 - 2.3e-14 53.3 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS31209.1 - 3e-07 30.0 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS31209.1 - 2e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDS31209.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CDS31209.1 - 0.12 12.0 0.2 0.67 9.5 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kunitz_BPTI PF00014.23 CDS31211.1 - 7.3e-29 99.8 16.5 8.4e-14 51.6 9.7 3.1 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3653 PF12375.8 CDS31212.1 - 0.28 11.3 1.2 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 Phage protein zf-H2C2_2 PF13465.6 CDS31213.2 - 1.8e-13 50.3 20.0 2.1e-10 40.5 0.9 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDS31213.2 - 2.2e-13 49.9 15.9 1.4e-05 25.2 1.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31213.2 - 3.9e-05 24.1 28.4 0.00093 19.8 1.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDS31213.2 - 0.19 12.1 16.3 0.75 10.1 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDS31213.2 - 0.28 11.5 6.6 1.3 9.4 0.5 2.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CDS31213.2 - 0.52 10.1 17.4 0.84 9.5 3.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDS31213.2 - 1 9.8 9.2 8.4 6.8 2.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS31213.2 - 1.6 8.9 10.3 21 5.3 2.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Snf7 PF03357.21 CDS31215.1 - 3.8e-16 59.2 9.7 5.2e-16 58.7 9.7 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CDS31215.1 - 6.1e-05 23.0 4.4 7.8e-05 22.7 4.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CENP-Q PF13094.6 CDS31215.1 - 0.083 13.1 2.7 0.15 12.2 2.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3447 PF11929.8 CDS31215.1 - 0.11 12.5 0.7 18 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Glyco_hydro_56 PF01630.18 CDS31215.1 - 0.12 11.3 0.7 0.16 11.0 0.7 1.1 1 0 0 1 1 1 0 Hyaluronidase bZIP_1 PF00170.21 CDS31216.1 - 3e-10 40.0 12.3 3e-10 40.0 12.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CDS31216.1 - 3.2e-06 27.1 10.4 3.2e-06 27.1 10.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS31216.1 - 0.0016 18.9 9.2 0.0016 18.9 9.2 1.8 2 0 0 2 2 1 1 bZIP Maf transcription factor DUF724 PF05266.14 CDS31216.1 - 0.0032 17.3 1.5 0.0083 16.0 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF724) ZapB PF06005.12 CDS31216.1 - 0.0036 17.7 3.6 0.0093 16.4 3.6 1.8 1 0 0 1 1 1 1 Cell division protein ZapB CCDC154 PF15450.6 CDS31216.1 - 0.0043 15.7 1.0 0.0061 15.2 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 KASH_CCD PF14662.6 CDS31216.1 - 0.0068 16.2 2.4 0.014 15.2 2.4 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 CDS31216.1 - 0.021 15.3 0.4 0.044 14.3 0.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Macoilin PF09726.9 CDS31216.1 - 0.036 12.6 4.2 0.054 12.1 4.2 1.1 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 CDS31216.1 - 0.046 13.9 4.9 0.095 12.9 4.9 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 CDS31216.1 - 0.046 14.1 0.4 0.18 12.2 0.4 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 CDS31216.1 - 0.052 13.8 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper GAS PF13851.6 CDS31216.1 - 0.056 12.8 2.4 0.1 11.9 2.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Latarcin PF10279.9 CDS31216.1 - 0.07 13.5 0.8 0.35 11.3 0.8 2.2 1 1 0 1 1 1 0 Latarcin precursor DivIC PF04977.15 CDS31216.1 - 0.071 12.9 0.7 0.19 11.5 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF3450 PF11932.8 CDS31216.1 - 0.084 12.2 2.0 0.15 11.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 CDS31216.1 - 0.15 12.7 0.9 0.33 11.6 0.9 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF4404 PF14357.6 CDS31216.1 - 0.51 11.0 5.5 43 4.8 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Pox_A_type_inc PF04508.12 CDS31216.1 - 1 9.4 10.3 1.9 8.5 1.7 3.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 CDS31217.1 - 4.2e-42 144.3 0.1 5.1e-22 78.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31217.1 - 6.3e-12 45.3 0.1 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS31217.1 - 0.016 14.2 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CDS31217.1 - 0.068 11.9 0.2 0.12 11.2 0.1 1.6 1 1 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 CDS31218.1 - 9.4e-09 35.8 3.1 0.083 13.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31218.1 - 0.0056 16.9 0.0 0.95 9.8 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Clathrin_propel PF01394.20 CDS31218.1 - 0.18 12.1 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Clathrin propeller repeat Sec15 PF04091.12 CDS31219.1 - 9.6e-52 176.3 0.0 5.7e-50 170.5 0.0 3.1 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 CDS31219.1 - 1.1e-06 28.6 1.6 2.8e-06 27.3 1.6 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 CDS31219.1 - 1.1e-05 25.5 2.0 1.1e-05 25.5 2.0 2.4 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 CDS31219.1 - 3.8e-05 22.5 6.0 6e-05 21.8 6.0 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 BLOC1_2 PF10046.9 CDS31219.1 - 0.00051 20.3 3.0 0.00051 20.3 3.0 3.2 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HLH PF00010.26 CDS31219.1 - 0.0049 16.8 2.2 7 6.7 1.8 3.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain MCPsignal PF00015.21 CDS31219.1 - 0.009 15.8 1.5 0.02 14.7 1.5 1.5 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain FlbT PF07378.11 CDS31219.1 - 0.0093 16.0 1.3 0.11 12.5 0.0 2.7 1 1 0 2 2 2 1 Flagellar protein FlbT Dor1 PF04124.12 CDS31219.1 - 0.011 14.4 4.4 0.02 13.6 4.4 1.4 1 0 0 1 1 1 0 Dor1-like family FliJ PF02050.16 CDS31219.1 - 0.02 15.1 4.2 0.099 12.9 1.7 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein STAT_alpha PF01017.20 CDS31219.1 - 0.092 12.6 4.4 0.29 11.0 4.4 1.8 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF1804 PF08822.11 CDS31219.1 - 0.1 12.6 1.3 0.37 10.8 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) Tup_N PF08581.10 CDS31219.1 - 0.12 12.7 6.8 0.68 10.3 4.1 2.9 2 0 0 2 2 2 0 Tup N-terminal Sec5 PF15469.6 CDS31219.1 - 0.17 11.7 1.4 0.39 10.5 1.4 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 TPR_MLP1_2 PF07926.12 CDS31219.1 - 0.31 11.1 6.5 0.13 12.3 3.4 2.0 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein PTPA PF03095.15 CDS31219.1 - 0.33 10.4 1.5 0.84 9.0 1.5 1.7 1 1 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Sec34 PF04136.15 CDS31219.1 - 0.51 10.2 7.4 1.6 8.6 2.9 3.4 3 0 0 3 3 3 0 Sec34-like family DUF3452 PF11934.8 CDS31219.1 - 0.7 9.5 3.5 1.7 8.2 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) Vps51 PF08700.11 CDS31219.1 - 1.1 9.4 6.2 0.41 10.8 0.8 3.0 3 1 0 3 3 3 0 Vps51/Vps67 COG5 PF10392.9 CDS31219.1 - 1.4 9.1 8.5 0.12 12.6 2.0 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 CDS31219.1 - 1.5 9.3 4.0 1.2 9.6 0.9 2.5 3 0 0 3 3 1 0 Nucleopolyhedrovirus P10 protein IP_trans PF02121.18 CDS31220.1 - 9.4e-105 349.6 0.2 1.1e-104 349.4 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PXA PF02194.15 CDS31221.1 - 1.6e-42 145.5 2.6 1.6e-42 145.5 2.6 2.3 2 0 0 2 2 2 1 PXA domain RRM_1 PF00076.22 CDS31221.1 - 2.8e-38 129.5 0.3 1.6e-09 37.5 0.0 6.0 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nexin_C PF08628.12 CDS31221.1 - 9.3e-23 80.9 0.3 5.3e-22 78.5 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CDS31221.1 - 8e-14 51.6 0.3 3.2e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 PX domain RRM_3 PF08777.11 CDS31221.1 - 2.6e-10 40.3 0.0 2.2 8.4 0.0 5.7 5 0 0 5 5 5 3 RNA binding motif RRM_7 PF16367.5 CDS31221.1 - 8.3e-10 38.7 2.2 0.66 10.1 0.0 6.2 6 0 0 6 6 5 1 RNA recognition motif RRM_occluded PF16842.5 CDS31221.1 - 1.3e-07 31.4 0.0 0.0013 18.6 0.0 3.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif RL PF17797.1 CDS31221.1 - 1.6e-05 24.7 0.1 1.1 9.2 0.1 4.9 5 0 0 5 5 5 2 RL domain DUF4523 PF15023.6 CDS31221.1 - 0.00014 21.7 0.5 0.2 11.5 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF4523) DUF1866 PF08952.11 CDS31221.1 - 0.00082 19.2 0.0 6.1 6.7 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 CDS31221.1 - 0.0011 18.9 0.0 7.8 6.6 0.0 4.7 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif zf-RING_UBOX PF13445.6 CDS31221.1 - 0.0051 16.8 10.9 0.018 15.1 10.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger RGS PF00615.19 CDS31221.1 - 0.013 15.8 0.0 0.17 12.1 0.0 3.0 2 1 0 2 2 2 0 Regulator of G protein signaling domain DUF489 PF04356.12 CDS31221.1 - 0.013 15.5 2.0 0.054 13.5 2.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Exonuc_VII_L PF02601.15 CDS31221.1 - 0.1 12.2 0.6 0.2 11.2 0.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RIC3 PF15361.6 CDS31221.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Rep_1 PF01446.17 CDS31221.1 - 0.14 11.6 1.4 0.28 10.6 1.4 1.5 1 0 0 1 1 1 0 Replication protein TMF_DNA_bd PF12329.8 CDS31221.1 - 0.62 10.1 5.7 0.34 10.9 3.0 2.0 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Trm112p PF03966.16 CDS31221.1 - 1.6 9.4 6.4 5.9 7.5 6.4 2.0 1 0 0 1 1 1 0 Trm112p-like protein zf-C3HC4_4 PF15227.6 CDS31221.1 - 2.4 8.4 22.7 0.042 14.0 13.4 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.13 CDS31221.1 - 8.6 4.1 6.2 13 3.5 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1664 PF07889.12 CDS31222.1 - 0.35 10.9 3.6 0.55 10.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) eIF3_N PF09440.10 CDS31222.1 - 0.4 11.1 6.9 0.2 12.1 2.2 2.6 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain zinc_ribbon_4 PF13717.6 CDS31222.1 - 3.2 7.7 17.9 0.39 10.7 0.3 4.8 3 2 1 4 4 4 0 zinc-ribbon domain 14-3-3 PF00244.20 CDS31223.1 - 2.2e-62 210.5 2.3 2.5e-62 210.3 2.3 1.0 1 0 0 1 1 1 1 14-3-3 protein FokI_N PF02981.15 CDS31223.1 - 0.08 13.1 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain VIT1 PF01988.19 CDS31223.1 - 0.51 10.2 3.4 3.7 7.4 0.3 2.1 2 0 0 2 2 2 0 VIT family FIVAR PF07554.13 CDS31223.1 - 0.88 10.4 4.3 7 7.5 0.1 3.3 4 0 0 4 4 4 0 FIVAR domain ABC_membrane PF00664.23 CDS31224.1 - 3.2e-38 132.0 2.0 5.9e-38 131.1 2.0 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDS31224.1 - 5.9e-33 114.3 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDS31224.1 - 3.5e-07 29.9 0.7 2.7e-05 23.7 0.1 2.7 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDS31224.1 - 0.00029 21.3 0.2 0.00062 20.2 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDS31224.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 CDS31224.1 - 0.0039 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDS31224.1 - 0.0041 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDS31224.1 - 0.0051 17.1 0.1 0.017 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDS31224.1 - 0.017 14.8 0.2 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDS31224.1 - 0.026 13.8 0.1 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CDS31224.1 - 0.04 13.5 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CDS31224.1 - 0.085 12.7 0.0 1.4 8.6 0.0 2.4 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CDS31224.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS31224.1 - 0.19 11.4 0.0 0.45 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain zf-CCCH PF00642.24 CDS31225.1 - 3.1e-16 58.8 12.1 3.9e-08 33.0 4.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDS31225.1 - 3.3e-09 36.3 12.6 2.4e-05 24.0 3.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDS31225.1 - 3.3e-08 33.3 10.0 3.7e-05 23.6 3.0 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 CDS31225.1 - 0.0084 16.6 8.4 0.13 12.7 0.9 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger DUF3324 PF11797.8 CDS31225.1 - 0.017 15.1 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Torus PF16131.5 CDS31225.1 - 0.16 12.7 7.4 1.4 9.6 1.8 2.3 1 1 1 2 2 2 0 Torus domain zf-CCHH PF10283.9 CDS31225.1 - 0.22 11.6 4.3 11 6.1 0.1 2.6 2 0 0 2 2 2 0 PBZ domain UCH PF00443.29 CDS31226.1 - 4.1e-23 82.2 0.0 1.7e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS31226.1 - 8.1e-12 45.4 2.3 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 CDS31226.1 - 0.17 11.8 1.9 2.1 8.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 CDS31227.1 - 9.3e-05 22.4 2.1 9.3e-05 22.4 2.1 2.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS31227.1 - 0.00029 20.6 2.8 0.00029 20.6 2.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS31227.1 - 0.00096 19.1 2.5 0.00096 19.1 2.5 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDS31227.1 - 0.0019 18.3 4.1 0.0019 18.3 4.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rootletin PF15035.6 CDS31227.1 - 0.0082 16.2 0.9 0.014 15.4 0.1 1.7 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion zf-C3HC4_2 PF13923.6 CDS31227.1 - 0.015 15.1 3.9 0.015 15.1 3.9 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COMMD1_N PF17221.3 CDS31227.1 - 0.032 14.5 0.2 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 COMMD1 N-terminal domain zf-RING_2 PF13639.6 CDS31227.1 - 0.042 14.2 4.0 0.042 14.2 4.0 2.5 2 1 0 2 2 2 0 Ring finger domain Mus7 PF09462.10 CDS31227.1 - 0.056 12.3 1.8 0.62 8.8 0.3 2.0 2 0 0 2 2 2 0 Mus7/MMS22 family zf-C3HC4_3 PF13920.6 CDS31227.1 - 0.61 10.0 11.3 0.45 10.4 4.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.9 CDS31227.1 - 3 8.2 11.3 0.22 11.8 5.7 2.0 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain RRM_1 PF00076.22 CDS31228.2 - 1.8e-46 155.8 0.1 7.1e-13 48.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDS31228.2 - 4e-08 33.2 0.0 0.01 15.9 0.0 3.6 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 CDS31228.2 - 2.1e-05 24.4 0.0 5.2 7.2 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDS31228.2 - 0.00077 19.3 0.4 0.054 13.4 0.1 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cript PF10235.9 CDS31228.2 - 0.0032 18.0 2.6 0.0093 16.5 2.6 1.8 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 CDS31228.2 - 0.03 15.1 2.1 0.068 13.9 2.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family Prok-RING_2 PF14445.6 CDS31228.2 - 0.094 12.9 2.6 0.2 11.8 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Dodecin PF07311.12 CDS31228.2 - 0.1 12.8 0.5 3.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Dodecin zf-HC5HC2H PF13771.6 CDS31228.2 - 0.13 12.5 4.2 0.34 11.2 4.2 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain NOB1_Zn_bind PF08772.11 CDS31228.2 - 0.26 11.5 4.5 0.79 9.9 4.5 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Siva PF05458.12 CDS31228.2 - 0.42 10.3 4.8 0.25 11.0 2.6 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zinc_ribbon_4 PF13717.6 CDS31232.2 - 0.032 14.2 0.2 0.032 14.2 0.2 1.1 1 0 0 1 1 1 0 zinc-ribbon domain PDZ PF00595.24 CDS31233.1 - 9.6e-11 41.9 0.0 3.3e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDS31233.1 - 3.2e-05 23.7 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS31233.1 - 7.3e-05 22.3 0.2 0.00038 20.0 0.2 2.2 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS31233.1 - 0.0009 18.9 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.6 CDS31233.1 - 0.025 14.9 0.0 0.073 13.4 0.0 1.7 2 0 0 2 2 2 0 PDZ domain SH3_9 PF14604.6 CDS31233.1 - 0.065 13.1 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 Variant SH3 domain mCpol PF18182.1 CDS31234.1 - 0.096 13.0 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 minimal CRISPR polymerase domain CRAL_TRIO PF00650.20 CDS31235.1 - 7.4e-09 35.5 0.0 9.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 CDS31236.2 - 1e-18 67.5 0.3 1.7e-18 66.9 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Egg_lysin PF01303.17 CDS31236.2 - 0.066 13.4 0.5 0.066 13.4 0.5 1.6 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) SET PF00856.28 CDS31238.1 - 1.1e-10 42.2 0.1 2.6e-10 40.9 0.1 1.9 1 1 0 1 1 1 1 SET domain CdiI_2 PF18593.1 CDS31238.1 - 0.032 14.9 0.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 CdiI immunity protein DUF29 PF01724.16 CDS31238.1 - 0.057 13.7 0.5 0.13 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Syntaxin_2 PF14523.6 CDS31238.1 - 0.076 13.4 1.3 0.18 12.2 0.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein RecG_N PF17190.4 CDS31238.1 - 3.3 8.5 6.9 9.2 7.1 3.0 2.5 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF2375 PF09558.10 CDS31240.2 - 0.12 12.4 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Roughex PF06020.11 CDS31240.2 - 2.5 7.1 7.4 5.4 6.0 1.1 2.1 2 0 0 2 2 2 0 Drosophila roughex protein DNA_pol_phi PF04931.13 CDS31240.2 - 6.5 4.7 7.0 11 4.0 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase phi COG5 PF10392.9 CDS31241.1 - 1.4e-06 28.5 1.0 6.6e-06 26.3 1.0 2.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 SET PF00856.28 CDS31242.1 - 1.1e-10 42.2 0.1 2.6e-10 40.9 0.1 1.9 1 1 0 1 1 1 1 SET domain CdiI_2 PF18593.1 CDS31242.1 - 0.032 14.9 0.0 0.41 11.3 0.0 2.4 2 0 0 2 2 2 0 CdiI immunity protein DUF29 PF01724.16 CDS31242.1 - 0.057 13.7 0.5 0.13 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Syntaxin_2 PF14523.6 CDS31242.1 - 0.076 13.4 1.3 0.18 12.2 0.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein RecG_N PF17190.4 CDS31242.1 - 3.3 8.5 6.9 9.2 7.1 3.0 2.5 2 0 0 2 2 2 0 RecG N-terminal helical domain Ion_trans PF00520.31 CDS31244.2 - 4.8e-46 157.0 12.2 1e-45 155.9 12.2 1.5 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDS31244.2 - 3.3e-28 97.9 0.1 8.4e-28 96.6 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDS31244.2 - 2.6e-13 49.7 5.4 2.6e-13 49.7 5.4 2.8 3 0 0 3 3 3 1 Ion channel BTB_3 PF16017.5 CDS31244.2 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain PKD_channel PF08016.12 CDS31244.2 - 0.22 10.1 7.1 0.015 14.0 1.2 1.8 1 1 1 2 2 2 0 Polycystin cation channel YrhC PF14143.6 CDS31244.2 - 0.29 11.3 2.2 0.63 10.2 0.2 2.4 2 0 0 2 2 2 0 YrhC-like protein Lipid_bd PF12888.7 CDS31248.1 - 0.12 12.8 0.2 0.34 11.3 0.1 1.7 2 0 0 2 2 2 0 Lipid-binding putative hydrolase MMR_HSR1 PF01926.23 CDS31249.1 - 6.6e-14 52.0 0.1 7.2e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS31249.1 - 1.8e-09 37.3 0.1 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDS31249.1 - 5.5e-06 26.4 0.0 0.032 14.1 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CDS31249.1 - 0.0002 20.7 0.2 0.00042 19.7 0.2 1.6 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CDS31249.1 - 0.0013 18.8 0.9 0.17 11.9 0.1 3.1 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 CDS31249.1 - 0.0014 18.2 0.6 0.12 11.9 0.0 3.4 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CDS31249.1 - 0.005 15.9 0.3 0.0087 15.1 0.3 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CDS31249.1 - 0.0062 16.1 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TatD_DNase PF01026.21 CDS31250.1 - 5.9e-54 183.1 0.0 7.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CDS31250.1 - 0.0032 17.3 0.1 0.011 15.6 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase TM2 PF05154.16 CDS31251.1 - 2.8e-16 59.6 6.7 4.4e-16 58.9 6.7 1.3 1 0 0 1 1 1 1 TM2 domain MCR PF18509.1 CDS31251.1 - 0.049 13.2 0.3 0.14 11.7 0.3 1.9 1 0 0 1 1 1 0 Magnetochrome domain PIH1 PF08190.12 CDS31252.1 - 0.0057 16.1 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 PIH1 N-terminal domain OTOS PF15182.6 CDS31252.1 - 0.029 14.3 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 Otospiralin Cas_Csa4 PF09703.10 CDS31252.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) Pkinase PF00069.25 CDS31253.1 - 2.3e-68 230.4 0.0 3.7e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31253.1 - 3e-31 108.7 0.0 5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS31253.1 - 1.6e-06 27.3 0.1 1.6e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CDS31253.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS31253.1 - 0.062 12.6 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CDS31253.1 - 0.1 11.3 0.8 0.3 9.8 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDS31253.1 - 0.18 10.7 2.6 0.25 10.3 0.5 1.9 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase PqqA PF08042.11 CDS31254.2 - 0.11 12.6 2.5 13 6.0 0.2 2.7 2 0 0 2 2 2 0 PqqA family DUF3736 PF12540.8 CDS31255.1 - 2.2 8.4 4.5 3 7.9 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) HLH PF00010.26 CDS31256.1 - 3.9e-12 45.9 11.6 9.9e-12 44.6 7.9 2.8 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.13 CDS31256.1 - 1.6e-10 41.0 1.1 2.3e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 Hairy Orange DNA_pol3_tau_4 PF12168.8 CDS31256.1 - 0.057 14.0 2.2 0.14 12.7 2.0 1.9 1 1 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding adh_short PF00106.25 CDS31257.1 - 1.7e-16 60.3 0.0 1.7e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS31257.1 - 1.7e-07 31.1 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA_12 PF13087.6 CDS31260.2 - 4.8e-119 395.2 0.0 3.7e-58 196.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDS31260.2 - 5.8e-82 275.4 19.1 5.2e-26 92.0 0.4 4.6 2 2 2 4 4 4 4 AAA domain UPF1_Zn_bind PF09416.10 CDS31260.2 - 2.7e-69 232.0 4.9 5.4e-69 231.0 4.9 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) UMPH-1 PF05822.12 CDS31260.2 - 4.3e-66 222.9 1.0 1e-65 221.7 1.0 1.7 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) AAA_30 PF13604.6 CDS31260.2 - 1.4e-20 73.9 0.0 9.9e-14 51.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDS31260.2 - 7e-16 58.9 0.2 2.6e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF5599 PF18141.1 CDS31260.2 - 5.7e-13 48.9 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) Viral_helicase1 PF01443.18 CDS31260.2 - 1.5e-11 44.5 0.0 0.15 11.8 0.0 5.3 5 0 0 5 5 5 4 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CDS31260.2 - 5.9e-08 32.9 0.0 5.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDS31260.2 - 2.4e-06 27.0 0.5 0.0029 16.9 0.0 4.2 4 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CDS31260.2 - 5.6e-06 26.3 0.1 0.0025 17.7 0.0 2.8 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 CDS31260.2 - 6.2e-05 23.3 0.3 0.0009 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CDS31260.2 - 0.00012 21.8 0.2 1.8 8.5 0.0 3.7 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CDS31260.2 - 0.0016 18.0 0.1 0.011 15.3 0.0 2.5 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 CDS31260.2 - 0.0045 16.7 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DEAD PF00270.29 CDS31260.2 - 0.01 15.6 0.6 0.056 13.2 0.1 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 CDS31260.2 - 0.025 14.0 0.0 0.072 12.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein CPSase_L_D2 PF02786.17 CDS31260.2 - 0.042 13.3 0.7 9.2 5.7 0.1 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AroM PF07302.11 CDS31260.2 - 0.087 12.2 0.1 18 4.7 0.0 2.5 2 0 0 2 2 2 0 AroM protein AAA_7 PF12775.7 CDS31260.2 - 0.12 11.8 0.2 0.5 9.9 0.0 2.1 3 0 0 3 3 1 0 P-loop containing dynein motor region PIF1 PF05970.14 CDS31260.2 - 0.14 11.3 0.1 54 2.8 0.0 3.1 3 0 0 3 3 3 0 PIF1-like helicase DUF4817 PF16087.5 CDS31260.2 - 0.15 11.9 0.0 33 4.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DUF732 PF05305.14 CDS31260.2 - 3.9 7.9 10.6 88 3.6 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF732) GIY-YIG PF01541.24 CDS31261.1 - 0.04 14.2 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain FANCL_C PF11793.8 CDS31261.1 - 0.13 12.4 1.8 0.26 11.5 1.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 CDS31261.1 - 0.68 10.3 4.3 3.1 8.2 4.3 2.0 1 1 0 1 1 1 0 RING-like domain MCRS_N PF13325.6 CDS31262.1 - 5.9e-31 108.0 0.1 3.8e-30 105.4 0.0 2.2 3 0 0 3 3 3 1 N-terminal region of micro-spherule protein Neur_chan_LBD PF02931.23 CDS31263.1 - 2.8e-59 200.2 0.9 4e-59 199.7 0.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS31263.1 - 1.4e-46 159.6 17.5 3e-44 151.9 17.5 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region LPD28 PF18843.1 CDS31263.1 - 0.077 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 polyprenyl_synt PF00348.17 CDS31265.1 - 1.4e-57 194.7 0.0 1.7e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Polysacc_synt PF01943.17 CDS31265.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 CDS31266.1 - 2.8e-19 68.7 0.1 6e-19 67.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS31266.1 - 1.1e-05 25.5 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif HTH_48 PF17906.1 CDS31267.1 - 2.8e-07 30.5 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase 7TM_GPCR_Srw PF10324.9 CDS31268.1 - 1.7e-15 57.1 20.8 1.1e-14 54.5 20.8 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS31268.1 - 2e-12 47.0 15.4 3.1e-12 46.4 15.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1679 PF07914.11 CDS31268.1 - 0.089 11.6 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SRF-TF PF00319.18 CDS31268.1 - 0.097 12.2 0.2 0.24 10.9 0.2 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) MH2 PF03166.14 CDS31269.1 - 1.5e-69 233.9 0.0 2.4e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 MH2 domain TIR_2 PF13676.6 CDS31270.1 - 2.2e-09 37.9 0.8 7.1e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 TIR domain SAM_2 PF07647.17 CDS31270.1 - 0.0079 16.3 0.2 0.027 14.6 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 CDS31270.1 - 0.051 13.4 0.5 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS31270.1 - 0.066 13.7 2.7 0.12 12.8 1.1 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4078 PF13300.6 CDS31273.1 - 1.9e-17 63.4 2.8 1.9e-17 63.4 2.8 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) zf-H2C2_2 PF13465.6 CDS31274.1 - 2.1e-12 46.9 11.2 7.4e-10 38.8 0.9 5.6 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS31274.1 - 2.1e-11 43.6 14.1 1e-06 28.9 4.4 5.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31274.1 - 7e-06 26.5 11.6 0.00036 21.1 3.5 5.3 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS31274.1 - 2.9e-05 23.9 2.2 2.9e-05 23.9 2.2 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS31274.1 - 0.013 15.3 2.0 0.013 15.3 2.0 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type HypA PF01155.19 CDS31274.1 - 0.2 11.7 8.4 0.068 13.2 3.9 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glycos_transf_1 PF00534.20 CDS31275.1 - 4.3e-27 94.7 0.0 2.2e-26 92.4 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDS31275.1 - 8.3e-11 42.5 0.0 1.7e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDS31275.1 - 4.7e-10 39.7 0.0 8.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDS31275.1 - 0.00037 21.0 0.0 0.0006 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CDS31275.1 - 0.011 16.1 0.0 0.04 14.3 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.5 CDS31275.1 - 0.025 14.2 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl-transferase family 4 bZIP_2 PF07716.15 CDS31276.1 - 5.5e-07 29.6 14.0 8.3e-07 29.0 14.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS31276.1 - 0.06 13.5 11.8 0.1 12.7 11.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor MatE PF01554.18 CDS31278.2 - 5.2e-40 136.7 25.0 3.7e-27 95.0 9.6 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CDS31278.2 - 4.1e-07 30.1 4.1 4.1e-07 30.1 4.1 3.9 2 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 CDS31278.2 - 1.5e-06 27.1 4.1 1.5e-06 27.1 4.1 2.4 2 1 0 2 2 2 1 Lipid II flippase MurJ MatE PF01554.18 CDS31279.1 - 3.4e-39 134.1 25.1 1.8e-19 70.0 7.6 2.6 2 0 0 2 2 2 2 MatE MatE PF01554.18 CDS31280.1 - 1.4e-42 145.1 32.1 3.7e-22 78.7 9.2 3.1 3 0 0 3 3 3 2 MatE FGF-BP1 PF06473.12 CDS31280.1 - 0.12 12.2 1.4 0.17 11.7 1.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Ank PF00023.30 CDS31281.1 - 3e-14 52.7 0.9 4.7e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 CDS31281.1 - 5.8e-13 49.2 0.0 1.4e-12 48.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS31281.1 - 3e-11 42.5 0.1 0.0013 19.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CDS31281.1 - 4.1e-09 36.8 0.0 0.0011 19.5 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS31281.1 - 5.7e-09 36.1 0.0 2.3e-05 24.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) MCM PF00493.23 CDS31282.1 - 3.6e-55 186.5 0.0 9.7e-54 181.8 0.0 2.3 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS31282.1 - 8.2e-17 61.2 1.8 2.1e-16 59.9 1.8 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS31282.1 - 5e-14 52.5 0.3 1.1e-13 51.4 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDS31282.1 - 0.0015 19.1 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDS31282.1 - 0.0018 17.7 0.1 0.027 13.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS31282.1 - 0.0082 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2039 PF10217.9 CDS31282.1 - 0.17 12.3 0.7 0.42 11.0 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) GDE_C PF06202.14 CDS31282.1 - 0.21 10.5 0.0 0.47 9.3 0.0 1.5 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Fz PF01392.22 CDS31283.1 - 0.51 11.0 9.4 0.076 13.6 4.4 2.2 2 1 0 2 2 2 0 Fz domain Myosin_head PF00063.21 CDS31284.1 - 4.2e-201 669.7 0.0 5.5e-201 669.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 CDS31284.1 - 4.9e-23 81.7 2.8 1e-19 71.0 0.2 3.8 2 1 0 2 2 2 2 MyTH4 domain IQ PF00612.27 CDS31284.1 - 5.2e-06 25.8 6.5 3.1e-05 23.4 0.1 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif FERM_M PF00373.18 CDS31284.1 - 0.00028 21.3 0.0 0.0011 19.4 0.0 2.2 1 0 0 1 1 1 1 FERM central domain AAA_22 PF13401.6 CDS31284.1 - 0.0096 16.2 0.2 0.19 12.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDS31284.1 - 0.1 13.0 0.0 0.5 10.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CDS31284.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CDS31284.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MRP-L46 PF11788.8 CDS31284.1 - 0.15 12.8 0.2 0.51 11.1 0.2 1.9 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF3781 PF12636.7 CDS31284.1 - 1.9 8.4 3.7 17 5.4 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) FERM_C PF09380.10 CDS31285.1 - 2.2e-06 28.0 0.1 4.2e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDS31285.1 - 2.6e-05 24.6 0.0 6.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 FERM central domain Nucleoside_tran PF01733.18 CDS31286.1 - 4.5e-58 197.1 7.5 1e-57 195.9 7.5 1.6 1 0 0 1 1 1 1 Nucleoside transporter Chorein_N PF12624.7 CDS31286.1 - 4.2e-23 81.7 0.1 6.5e-22 77.8 0.0 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CDS31286.1 - 1.1e-22 80.6 0.2 1.1e-22 80.6 0.2 3.0 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal RVT_1 PF00078.27 CDS31287.1 - 2.1e-10 40.5 0.0 6.9e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rtf2 PF04641.12 CDS31289.1 - 3.5e-70 236.4 7.7 6.3e-70 235.5 7.7 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CDS31289.1 - 0.00045 20.3 0.1 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 CDS31289.1 - 0.0076 16.1 0.4 0.081 12.8 0.3 2.3 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit FAM212 PF15342.6 CDS31289.1 - 0.14 12.0 0.0 0.58 10.0 0.0 2.1 1 0 0 1 1 1 0 FAM212 family Myosin_head PF00063.21 CDS31290.2 - 1.9e-41 142.1 0.0 4.2e-19 68.2 0.0 4.2 4 0 0 4 4 4 4 Myosin head (motor domain) PDZ_6 PF17820.1 CDS31290.2 - 4e-05 23.4 0.1 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CDS31290.2 - 0.0021 18.4 0.1 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Cnn_1N PF07989.11 CDS31290.2 - 0.0068 16.5 4.6 0.0068 16.5 4.6 4.1 2 2 1 3 3 3 1 Centrosomin N-terminal motif 1 NACHT PF05729.12 CDS31290.2 - 0.015 15.2 0.2 6.5 6.6 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 CDS31290.2 - 0.066 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CDS31290.2 - 0.11 12.5 0.0 0.11 12.5 0.0 3.6 2 1 0 2 2 2 0 Helicase HerA, central domain PDZ_2 PF13180.6 CDS31290.2 - 0.17 12.3 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 PDZ domain HOOK PF05622.12 CDS31290.2 - 0.95 7.5 44.4 1.7 6.7 44.4 1.3 1 0 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 CDS31290.2 - 8.3 6.5 17.2 14 5.7 1.9 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.32 CDS31291.1 - 2.6e-19 69.2 1.9 2.2e-06 28.3 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31291.1 - 0.0003 21.0 0.0 0.025 14.9 0.0 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDS31291.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain EF-hand_6 PF13405.6 CDS31292.2 - 2.4e-17 61.3 0.1 1.4e-06 27.7 0.0 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CDS31292.2 - 2.4e-17 61.1 0.1 1e-05 24.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CDS31292.2 - 1.3e-15 57.6 0.1 6.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS31292.2 - 1.4e-12 46.5 0.1 5.8e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDS31292.2 - 1.9e-08 34.0 0.5 0.00025 20.8 0.0 3.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CDS31292.2 - 0.00062 20.0 0.0 3.3 8.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain bZIP_2 PF07716.15 CDS31293.1 - 2.7e-09 37.0 9.5 5.9e-09 35.9 9.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS31293.1 - 8.6e-09 35.4 6.9 1.6e-08 34.5 6.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF4618 PF15397.6 CDS31293.1 - 0.0015 18.0 0.4 0.0022 17.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_Maf PF03131.17 CDS31293.1 - 0.012 16.1 5.9 0.022 15.2 5.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor MIF4G_like_2 PF09090.11 CDS31293.1 - 0.017 14.6 0.5 0.024 14.1 0.5 1.2 1 0 0 1 1 1 0 MIF4G like HALZ PF02183.18 CDS31293.1 - 0.047 13.9 2.4 0.085 13.1 2.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper UMP1 PF05348.11 CDS31294.1 - 2.9e-14 53.3 0.1 3.2e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cadherin PF00028.17 CDS31295.1 - 4.4e-79 261.0 0.9 2.6e-15 56.6 0.0 9.2 9 0 0 9 9 9 8 Cadherin domain Cadherin_2 PF08266.12 CDS31295.1 - 4.9e-11 42.3 0.2 0.00058 19.7 0.0 4.8 5 0 0 5 5 5 3 Cadherin-like Cadherin_4 PF17803.1 CDS31295.1 - 0.99 10.1 8.1 7.3 7.3 0.1 5.0 6 0 0 6 6 6 0 Bacterial cadherin-like domain LicD PF04991.13 CDS31297.2 - 2.6e-12 47.4 0.6 6.9e-09 36.2 0.1 2.4 1 1 1 2 2 2 2 LicD family LicD PF04991.13 CDS31298.2 - 5e-15 56.3 0.5 5.1e-12 46.4 0.2 2.2 1 1 1 2 2 2 2 LicD family ASFV_360 PF01671.16 CDS31304.2 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein DEAD PF00270.29 CDS31307.1 - 9.5e-46 155.8 0.0 2.1e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31307.1 - 2.8e-27 95.3 0.0 1.4e-26 93.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31307.1 - 0.0039 17.2 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DCB PF16213.5 CDS31307.1 - 0.21 11.2 1.5 1.5 8.4 0.3 2.2 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SR-25 PF10500.9 CDS31307.1 - 2.2 7.8 25.6 4.8 6.7 25.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.6 CDS31308.1 - 1.1e-08 35.1 23.4 6e-06 26.5 0.3 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS31308.1 - 1.2e-05 25.5 36.4 0.00017 21.8 2.0 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CDS31308.1 - 0.1 13.0 7.9 0.28 11.7 0.9 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_4 PF07975.12 CDS31308.1 - 0.13 12.5 4.8 6.5 7.1 0.0 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 CDS31308.1 - 0.28 11.2 19.5 0.11 12.5 2.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.22 CDS31308.1 - 3.2 8.0 11.0 38 4.6 0.3 3.1 2 1 1 3 3 3 0 LIM domain zf_C2H2_ZHX PF18387.1 CDS31308.1 - 3.5 7.3 12.6 0.4 10.4 0.7 3.5 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HNH_5 PF14279.6 CDS31308.1 - 5.2 7.0 8.0 19 5.2 1.6 3.1 3 0 0 3 3 3 0 HNH endonuclease Exo_endo_phos_2 PF14529.6 CDS31313.1 - 4.4e-11 42.7 0.1 6.9e-11 42.0 0.1 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS31313.1 - 0.00012 21.7 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.26 CDS31314.1 - 1e-09 38.3 36.5 0.0018 18.7 3.3 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31314.1 - 6.3e-08 32.7 34.8 6.5e-05 23.2 3.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31314.1 - 9.6e-05 22.9 34.0 0.1 13.5 2.0 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger LIM PF00412.22 CDS31314.1 - 0.077 13.2 13.2 5 7.4 3.9 3.4 2 1 1 3 3 3 0 LIM domain FAM220 PF15487.6 CDS31314.1 - 0.81 9.3 5.6 1.6 8.3 5.6 1.4 1 0 0 1 1 1 0 FAM220 family zf-Di19 PF05605.12 CDS31314.1 - 1.8 8.9 22.8 2 8.8 0.4 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 CDS31314.1 - 2.7 7.7 6.8 1.3 8.7 3.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_3rep PF18868.1 CDS31314.1 - 3.2 8.4 8.6 1.1 10.0 4.3 2.2 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDS31314.1 - 6.1 7.0 23.0 2.2 8.4 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS31314.1 - 6.8 7.1 15.7 1.3 9.4 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDS31316.1 - 0.05 14.1 0.4 0.05 14.1 0.4 6.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 CDS31317.1 - 0.05 14.1 0.4 0.05 14.1 0.4 6.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 CDS31320.1 - 1e-09 38.3 36.5 0.0018 18.7 3.3 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31320.1 - 6.3e-08 32.7 34.8 6.5e-05 23.2 3.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31320.1 - 9.6e-05 22.9 34.0 0.1 13.5 2.0 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger LIM PF00412.22 CDS31320.1 - 0.077 13.2 13.2 5 7.4 3.9 3.4 2 1 1 3 3 3 0 LIM domain FAM220 PF15487.6 CDS31320.1 - 0.81 9.3 5.6 1.6 8.3 5.6 1.4 1 0 0 1 1 1 0 FAM220 family zf-Di19 PF05605.12 CDS31320.1 - 1.8 8.9 22.8 2 8.8 0.4 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.9 CDS31320.1 - 2.7 7.7 6.8 1.3 8.7 3.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_3rep PF18868.1 CDS31320.1 - 3.2 8.4 8.6 1.1 10.0 4.3 2.2 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDS31320.1 - 6.1 7.0 23.0 2.2 8.4 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS31320.1 - 6.8 7.1 15.7 1.3 9.4 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SMP_LBD PF17047.5 CDS31321.1 - 1.3e-39 135.5 0.2 2e-39 135.0 0.2 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 CDS31321.1 - 1.3e-35 121.8 0.1 4.2e-21 75.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain MLVIN_C PF18697.1 CDS31321.1 - 0.08 13.0 0.0 14 5.9 0.0 3.0 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Usp PF00582.26 CDS31323.1 - 2.2e-25 89.8 0.0 2.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Prefoldin_2 PF01920.20 CDS31323.1 - 0.0072 16.3 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit MmcB-like PF06319.12 CDS31323.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein MmcB-like Pkinase PF00069.25 CDS31324.1 - 1.4e-45 155.7 0.0 1.7e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31324.1 - 9.6e-25 87.3 0.0 1.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31324.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS31324.1 - 0.0021 17.5 0.9 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS31324.1 - 0.03 14.3 0.2 0.054 13.4 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CDS31324.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CDS31324.1 - 0.13 11.8 0.3 20 4.7 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_1 PF00036.32 CDS31325.1 - 7.1e-24 81.5 5.9 1.2e-08 33.9 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDS31325.1 - 5.2e-20 69.6 3.5 1.4e-08 34.0 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CDS31325.1 - 4.4e-19 68.7 0.1 2.6e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS31325.1 - 2.3e-15 55.3 6.1 6.3e-07 28.6 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS31325.1 - 6.3e-11 42.0 5.3 9.4e-06 25.4 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CDS31325.1 - 2.7e-07 30.8 0.1 5.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CDS31325.1 - 0.00013 21.9 0.1 0.0016 18.4 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS31325.1 - 0.035 14.4 0.0 2 8.8 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDS31325.1 - 0.056 13.4 0.1 0.85 9.5 0.0 2.2 1 1 0 2 2 2 0 Caleosin related protein EF-hand_14 PF17959.1 CDS31325.1 - 0.06 13.7 0.1 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain FGAR-AT_linker PF18072.1 CDS31325.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain PQ-loop PF04193.14 CDS31326.1 - 3.5e-28 97.1 15.6 1.3e-15 56.9 2.3 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 CDS31326.1 - 0.018 15.0 0.7 0.018 15.0 0.7 2.8 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange HisKA_7TM PF16927.5 CDS31326.1 - 0.028 14.5 11.8 1.3 9.0 3.7 2.5 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase PQ-loop PF04193.14 CDS31327.1 - 4.3e-28 96.9 12.3 1.8e-16 59.7 2.6 3.4 3 1 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CDS31327.1 - 7.3e-05 22.7 3.1 0.0002 21.3 3.1 1.7 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange HTH_Bact PF18768.1 CDS31327.1 - 1.6 8.4 3.2 3 7.5 1.0 2.6 2 1 1 3 3 3 0 Helix-turn-helix bacterial domain TIR_2 PF13676.6 CDS31328.1 - 5e-16 59.4 0.0 1.4e-15 58.0 0.0 1.8 1 1 0 1 1 1 1 TIR domain TIR PF01582.20 CDS31328.1 - 0.0053 16.6 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 TIR domain SAM_1 PF00536.30 CDS31328.1 - 0.0063 16.9 0.2 0.022 15.2 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) V-ATPase_H_N PF03224.14 CDS31328.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H SAM_3 PF18016.1 CDS31328.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HEAT PF02985.22 CDS31330.2 - 0.023 14.9 0.2 3e+02 2.1 0.0 5.3 4 0 0 4 4 4 0 HEAT repeat DUF1959 PF09218.10 CDS31330.2 - 0.042 14.0 0.1 23 5.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Erg28 PF03694.13 CDS31330.2 - 0.078 13.4 0.3 39 4.7 0.0 3.3 2 0 0 2 2 2 0 Erg28 like protein CENP-H PF05837.12 CDS31330.2 - 0.68 10.4 11.7 7.8 6.9 2.2 3.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NCBP3 PF10309.9 CDS31331.1 - 2.6e-13 49.6 0.5 4.5e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CDS31331.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain PipA PF07108.11 CDS31332.2 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 PipA protein DUF2967 PF11179.8 CDS31332.2 - 0.19 9.8 1.4 0.22 9.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF1232 PF06803.12 CDS31334.1 - 2.6e-07 30.3 8.0 4e-07 29.7 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) NDK PF00334.19 CDS31335.1 - 2.3e-14 53.6 0.1 3e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 CDS31335.1 - 3.2e-13 49.1 0.2 6.3e-13 48.2 0.1 1.5 2 0 0 2 2 2 1 Dpy-30 motif DUF1934 PF09148.10 CDS31336.1 - 0.018 15.0 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1934) Pox_TAA1 PF03295.14 CDS31336.1 - 0.019 14.8 0.0 0.061 13.2 0.0 1.9 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal DUF2098 PF09871.9 CDS31336.1 - 0.81 10.1 3.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) 6PF2K PF01591.18 CDS31337.1 - 4.3e-73 245.3 6.0 5.8e-73 244.9 6.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CDS31337.1 - 1.7e-37 129.0 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CDS31337.1 - 0.17 12.1 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 CDS31338.1 - 3.9e-28 96.3 29.8 1.6e-05 25.1 0.6 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31338.1 - 1.4e-18 65.9 29.4 0.00032 21.3 0.3 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS31338.1 - 2.1e-17 62.6 23.1 2.7e-06 27.5 0.1 6.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS31338.1 - 8.9e-11 41.8 16.2 0.038 14.3 0.0 5.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS31338.1 - 8.5e-10 38.7 19.7 0.0042 17.4 0.2 5.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDS31338.1 - 8.5e-09 35.2 25.2 0.0053 16.7 0.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 CDS31338.1 - 1.5e-07 31.7 14.8 0.014 15.8 0.0 5.3 2 1 3 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 CDS31338.1 - 0.011 16.0 21.6 0.66 10.3 5.7 3.7 2 1 2 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 CDS31338.1 - 0.02 15.7 0.6 0.02 15.7 0.6 3.3 2 1 0 2 2 1 0 zinc-ribbon family DUF4764 PF15961.5 CDS31338.1 - 0.059 12.1 7.2 0.1 11.3 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) Zn-ribbon_8 PF09723.10 CDS31338.1 - 0.084 13.0 0.5 0.084 13.0 0.5 4.3 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 CDS31338.1 - 0.12 12.3 0.3 0.12 12.3 0.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 CDS31338.1 - 0.2 11.8 7.8 15 5.8 0.0 4.5 1 1 3 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 CDS31338.1 - 0.25 11.1 25.3 1.7 8.5 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CDS31338.1 - 0.38 11.1 20.9 0.43 10.9 0.5 4.7 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 CDS31338.1 - 1.6 9.0 18.0 0.23 11.7 1.6 3.9 3 1 0 3 3 3 0 TFIIH C1-like domain Zf_RING PF16744.5 CDS31338.1 - 3.3 7.9 19.7 1.8 8.7 1.6 4.1 2 1 3 5 5 5 0 KIAA1045 RING finger HypA PF01155.19 CDS31338.1 - 6.2 6.9 17.6 2.8e+02 1.5 9.4 3.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 CDS31338.1 - 6.5 6.9 28.5 2.6 8.1 1.2 5.3 3 1 1 4 4 4 0 BED zinc finger FYVE PF01363.21 CDS31338.1 - 7.8 6.7 24.6 2.9e+02 1.7 5.6 4.1 1 1 2 3 3 3 0 FYVE zinc finger zf-AN1 PF01428.16 CDS31338.1 - 9.4 6.5 21.4 34 4.7 0.5 5.4 5 0 0 5 5 5 0 AN1-like Zinc finger Ank_2 PF12796.7 CDS31339.2 - 4e-144 469.6 45.6 7.1e-18 65.0 0.2 11.5 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS31339.2 - 7e-128 415.0 45.7 3.8e-10 39.8 0.0 18.8 3 3 13 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 CDS31339.2 - 2.4e-125 404.0 64.6 2.1e-08 34.3 0.1 22.6 21 1 1 22 22 22 22 Ankyrin repeat Ank_3 PF13606.6 CDS31339.2 - 7.6e-115 360.8 38.8 3.7e-06 26.9 0.1 23.0 23 0 0 23 23 23 20 Ankyrin repeat Ank_4 PF13637.6 CDS31339.2 - 1.2e-111 363.7 37.9 1.2e-13 51.2 0.6 15.8 7 5 10 17 17 17 17 Ankyrin repeats (many copies) UPA_2 PF17809.1 CDS31339.2 - 4.7e-45 152.6 0.0 1.2e-44 151.3 0.0 1.8 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 CDS31339.2 - 6e-32 109.9 0.2 2.1e-23 82.5 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 CDS31339.2 - 4.9e-10 39.4 0.1 1.1e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Death domain MFS_1 PF07690.16 CDS31341.1 - 2.3e-19 69.5 39.5 2.3e-15 56.4 15.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sod_Cu PF00080.20 CDS31342.1 - 2.8e-48 163.7 4.1 3.2e-48 163.5 4.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SPAN PF02510.14 CDS31342.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein Lactamase_B_2 PF12706.7 CDS31343.2 - 2.9e-14 53.0 0.3 1e-12 48.0 0.3 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDS31343.2 - 1.4e-07 31.7 0.1 2.8e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CDS31343.2 - 0.076 12.4 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Laminin_N PF00055.17 CDS31346.2 - 6.2e-48 163.4 0.0 6.2e-48 163.4 0.0 3.3 4 1 0 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CDS31346.2 - 6.7e-30 103.0 80.0 1.8e-09 37.6 16.0 5.4 5 0 0 5 5 5 4 Laminin EGF domain NTR PF01759.21 CDS31346.2 - 0.0098 15.7 0.1 0.3 10.9 0.1 2.5 1 1 0 1 1 1 1 UNC-6/NTR/C345C module EGF_2 PF07974.13 CDS31346.2 - 0.019 15.3 5.9 0.019 15.3 5.9 8.3 8 2 1 9 9 9 0 EGF-like domain BNR_6 PF15899.5 CDS31346.2 - 0.052 13.6 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 BNR-Asp box repeat Pkinase PF00069.25 CDS31347.1 - 1.7e-26 93.2 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31347.1 - 4.5e-15 55.6 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS31347.1 - 1.1e-09 37.5 1.4 1.6e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDS31347.1 - 0.0048 16.8 0.1 0.055 13.4 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family HEAT_2 PF13646.6 CDS31349.1 - 7.4e-16 58.3 7.8 1.1e-07 32.1 0.2 3.7 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CDS31349.1 - 2.2e-10 39.9 3.1 0.067 13.5 0.1 4.5 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.16 CDS31349.1 - 5.2e-09 35.9 19.4 0.0093 16.5 0.1 6.7 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CDS31349.1 - 0.0032 17.9 11.6 0.46 11.1 0.7 5.4 4 3 2 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 CDS31349.1 - 0.004 17.2 0.0 23 5.0 0.0 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CH PF00307.31 CDS31350.1 - 1.1e-14 54.5 0.2 1.6e-14 54.0 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.17 CDS31350.1 - 1.1e-12 47.9 1.4 2.9e-12 46.6 0.8 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CAMSAP_CH PF11971.8 CDS31350.1 - 0.002 17.9 0.1 0.0049 16.7 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain DUF4250 PF14056.6 CDS31350.1 - 0.0039 17.1 1.5 5.6 7.0 0.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4250) CH_2 PF06294.11 CDS31350.1 - 0.041 14.0 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein Cep57_CLD_2 PF14197.6 CDS31350.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Kelch_1 PF01344.25 CDS31353.1 - 3.8e-11 42.4 0.5 4.9e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CDS31353.1 - 1.1e-08 34.9 2.2 0.0012 18.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 CDS31353.1 - 8.8e-07 29.1 0.0 2.6e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 CDS31353.1 - 9.3e-05 22.6 1.3 0.51 10.7 0.0 2.8 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CDS31353.1 - 0.0022 17.9 0.7 0.076 13.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif DUF1199 PF06712.11 CDS31353.1 - 0.052 13.6 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) BACK PF07707.15 CDS31353.1 - 0.14 12.3 0.1 3.9 7.6 0.0 2.3 1 1 1 2 2 2 0 BTB And C-terminal Kelch FHA PF00498.26 CDS31354.2 - 0.059 13.7 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 FHA domain Kelch_1 PF01344.25 CDS31355.1 - 3.5e-21 74.5 11.9 1.3e-11 43.9 0.0 5.7 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDS31355.1 - 3.1e-14 52.7 4.0 8.8e-07 29.0 0.0 5.2 4 1 1 5 5 5 2 Kelch motif BTB PF00651.31 CDS31355.1 - 1.4e-10 41.3 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CDS31355.1 - 8.1e-10 38.5 4.5 0.00051 20.0 0.4 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDS31355.1 - 1.2e-07 31.9 0.0 0.0067 16.7 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS31355.1 - 3.9e-06 26.8 0.1 0.02 14.9 0.0 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain BACK PF07707.15 CDS31355.1 - 3.9e-05 23.7 0.0 0.018 15.1 0.0 2.4 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDS31355.1 - 0.00017 21.4 4.5 0.076 13.0 0.0 4.6 5 0 0 5 5 5 1 Kelch motif PQQ_3 PF13570.6 CDS31355.1 - 0.077 13.5 0.2 0.73 10.4 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain Kelch_1 PF01344.25 CDS31357.2 - 3.7e-21 74.4 11.9 1.3e-11 43.9 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDS31357.2 - 3.3e-14 52.6 4.0 8.8e-07 29.0 0.0 5.1 4 1 1 5 5 5 2 Kelch motif BTB PF00651.31 CDS31357.2 - 1.2e-10 41.6 0.0 3.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CDS31357.2 - 7.7e-10 38.5 4.5 0.00051 20.0 0.4 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDS31357.2 - 1.2e-07 31.8 0.0 0.0067 16.7 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS31357.2 - 4.6e-06 26.5 0.1 0.02 14.9 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain BACK PF07707.15 CDS31357.2 - 3.9e-05 23.7 0.0 0.018 15.1 0.0 2.4 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDS31357.2 - 5e-05 23.1 3.2 0.076 13.0 0.0 4.6 5 0 0 5 5 5 1 Kelch motif PQQ_3 PF13570.6 CDS31357.2 - 0.086 13.4 0.2 0.73 10.4 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain NAD_Gly3P_dh_N PF01210.23 CDS31359.1 - 0.016 15.2 0.1 0.047 13.7 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Kelch_1 PF01344.25 CDS31360.1 - 1.5e-13 50.1 1.8 1.2e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CDS31360.1 - 6.9e-11 41.9 0.6 8.7e-06 25.6 0.2 2.6 2 0 0 2 2 2 2 Kelch motif BACK PF07707.15 CDS31360.1 - 4.3e-08 33.2 0.2 2.4e-05 24.4 0.0 2.4 1 1 1 2 2 2 2 BTB And C-terminal Kelch Kelch_6 PF13964.6 CDS31360.1 - 1.1e-06 28.7 0.6 0.035 14.4 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDS31360.1 - 0.00012 22.0 0.0 0.33 11.0 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain BTB PF00651.31 CDS31360.1 - 0.00031 20.9 0.0 0.00069 19.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDS31360.1 - 0.00062 19.6 0.4 0.32 11.0 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CDS31360.1 - 0.0014 18.9 0.0 0.74 10.2 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF2023 PF09633.10 CDS31360.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Myosin_head PF00063.21 CDS31362.1 - 2.4e-212 706.9 3.7 3.9e-212 706.2 3.7 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CDS31362.1 - 3.1e-22 78.8 3.3 5e-22 78.2 0.5 3.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CDS31362.1 - 4.7e-05 22.8 11.9 8e-05 22.1 2.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_16 PF13191.6 CDS31362.1 - 0.0084 16.5 0.0 0.054 13.9 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDS31362.1 - 0.046 14.0 0.0 0.28 11.4 0.0 2.5 1 0 0 1 1 1 0 AAA domain SCAMP PF04144.13 CDS31363.2 - 3.8e-49 167.3 15.5 4.5e-49 167.1 15.5 1.1 1 0 0 1 1 1 1 SCAMP family DUF4149 PF13664.6 CDS31363.2 - 0.023 15.0 6.6 0.023 15.0 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) PLDc_N PF13396.6 CDS31363.2 - 0.42 10.6 4.3 2.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal DUF2070 PF09843.9 CDS31363.2 - 0.76 8.0 6.5 1 7.6 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DuoxA PF10204.9 CDS31363.2 - 2.9 6.8 12.3 0.19 10.7 6.3 2.1 1 1 2 3 3 3 0 Dual oxidase maturation factor Mem_trans PF03547.18 CDS31364.1 - 2e-12 46.2 25.5 2.7e-07 29.3 4.2 3.0 2 1 1 3 3 3 2 Membrane transport protein zf-H2C2_2 PF13465.6 CDS31368.2 - 1e-06 28.9 18.6 0.0003 21.1 2.8 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDS31368.2 - 6.3e-05 23.2 4.2 6.3e-05 23.2 4.2 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31368.2 - 0.0098 16.7 3.2 0.0098 16.7 3.2 4.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CDS31368.2 - 0.095 13.1 0.3 0.095 13.1 0.3 3.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2225 PF09986.9 CDS31368.2 - 0.67 9.6 4.1 0.98 9.1 2.6 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.8 CDS31368.2 - 0.68 10.3 7.1 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDS31369.1 - 1.2e-05 25.5 9.9 0.0019 18.5 0.5 3.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31369.1 - 0.0046 17.7 10.5 1.3 10.1 0.6 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CDS31369.1 - 0.0051 17.2 5.6 0.87 10.1 1.4 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDS31369.1 - 0.056 13.8 3.3 0.81 10.1 0.1 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CDS31369.1 - 1.2 9.7 8.1 4.2 8.0 0.6 4.1 3 0 0 3 3 3 0 Zinc-finger double domain HTH_46 PF15977.5 CDS31372.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding HTH_46 PF15977.5 CDS31377.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA binding UL42 PF17638.2 CDS31378.1 - 0.12 12.4 3.9 0.098 12.6 2.5 1.6 2 0 0 2 2 2 0 HCMV UL42 DUF1150 PF06620.11 CDS31380.1 - 0.066 13.4 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) Molydop_binding PF01568.21 CDS31380.1 - 0.13 12.3 0.1 1.4 9.0 0.0 2.1 1 1 0 2 2 2 0 Molydopterin dinucleotide binding domain PRP4 PF08799.11 CDS31381.2 - 2.6e-07 30.1 0.0 5.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF2712 PF10916.8 CDS31381.2 - 0.16 12.7 0.1 0.28 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) Kelch_1 PF01344.25 CDS31382.1 - 3e-16 58.7 2.4 7.8e-06 25.4 0.0 4.8 4 2 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDS31382.1 - 4.1e-11 42.8 0.1 9e-05 22.6 0.0 3.4 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CDS31382.1 - 5.9e-06 26.1 0.1 0.00095 19.1 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CDS31382.1 - 8.8e-05 22.4 0.3 0.0075 16.3 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS31382.1 - 0.00016 21.5 0.0 1.4 9.1 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CDS31382.1 - 0.084 13.2 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain RII_binding_1 PF10522.9 CDS31383.2 - 0.55 10.6 2.1 9.9 6.7 0.1 3.5 3 0 0 3 3 3 0 RII binding domain SH3_10 PF17902.1 CDS31384.2 - 1.4e-07 31.5 0.0 4.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain ERM PF00769.19 CDS31384.2 - 0.0072 16.2 0.8 0.026 14.4 0.8 2.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Sipho_Gp157 PF05565.11 CDS31384.2 - 0.012 15.6 1.2 0.036 14.1 1.2 1.7 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4200 PF13863.6 CDS31384.2 - 0.094 13.1 9.8 0.039 14.4 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3071 PF11268.8 CDS31384.2 - 0.097 12.7 2.0 0.31 11.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) Mod_r PF07200.13 CDS31384.2 - 9.1 6.4 11.7 0.64 10.1 5.2 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spt5_N PF11942.8 CDS31385.2 - 0.083 13.9 9.3 0.15 13.0 9.3 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal FYDLN_acid PF09538.10 CDS31385.2 - 0.7 10.6 11.3 1.3 9.8 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Astro_capsid_p PF12226.8 CDS31385.2 - 2.8 7.0 12.0 4.2 6.4 12.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 CDS31385.2 - 4.8 6.3 6.3 7.4 5.7 6.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ALAD PF00490.21 CDS31386.1 - 5.3e-110 367.5 0.0 5.9e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ThiF PF00899.21 CDS31387.1 - 8.4e-51 172.7 0.0 1.2e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 CDS31387.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDS31387.1 - 0.005 17.1 2.3 0.08 13.2 0.5 3.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDS31387.1 - 0.006 17.0 0.3 0.085 13.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 CDS31387.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PLAC8 PF04749.17 CDS31388.1 - 0.00091 20.2 0.5 0.0013 19.7 0.5 1.2 1 0 0 1 1 1 1 PLAC8 family AF-4 PF05110.13 CDS31388.1 - 0.48 8.4 9.8 0.49 8.4 9.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein C2 PF00168.30 CDS31389.2 - 5.2e-11 42.7 0.0 9.5e-07 29.1 0.1 2.5 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDS31389.2 - 0.067 12.8 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain C2 PF00168.30 CDS31390.1 - 2.7e-05 24.4 0.0 0.062 13.6 0.0 2.7 2 0 0 2 2 2 2 C2 domain SR-25 PF10500.9 CDS31390.1 - 0.12 12.0 7.0 0.24 11.0 7.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TIR_2 PF13676.6 CDS31391.1 - 0.0021 18.6 0.0 0.011 16.4 0.0 2.2 1 1 0 1 1 1 1 TIR domain Peptidase_S66C PF17676.1 CDS31391.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain DUF5578 PF17741.1 CDS31392.1 - 3.5e-114 380.8 0.2 4.7e-114 380.3 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5578) HEAT_2 PF13646.6 CDS31392.1 - 0.31 11.4 1.3 8.7 6.8 0.1 2.6 1 1 1 2 2 2 0 HEAT repeats TFIIE_alpha PF02002.17 CDS31393.1 - 6.8e-16 58.0 6.0 1.1e-15 57.4 6.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit Imm64 PF15600.6 CDS31393.1 - 0.0041 16.8 0.7 0.011 15.4 0.2 1.8 1 1 1 2 2 2 1 Immunity protein 64 DUF1677 PF07911.13 CDS31393.1 - 0.033 14.6 0.4 0.085 13.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) zf-CHY PF05495.12 CDS31393.1 - 0.061 13.8 1.9 0.14 12.6 1.9 1.6 1 0 0 1 1 1 0 CHY zinc finger TF_Zn_Ribbon PF08271.12 CDS31393.1 - 0.14 11.7 3.6 0.28 10.7 3.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Elf1 PF05129.13 CDS31393.1 - 0.18 11.9 1.8 0.4 10.7 1.8 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TCR PF03638.15 CDS31394.1 - 8e-24 83.7 53.6 4.4e-12 46.1 21.7 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 CDS31394.1 - 0.0033 17.5 44.2 0.013 15.7 17.6 2.5 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 RhoGAP PF00620.27 CDS31395.1 - 4e-30 104.7 0.0 1e-28 100.1 0.0 2.7 1 1 0 1 1 1 1 RhoGAP domain D123 PF07065.14 CDS31395.1 - 2.1 7.4 6.2 0.18 10.9 0.3 2.0 2 0 0 2 2 2 0 D123 Endonuclease_5 PF04493.14 CDS31396.1 - 8.4e-07 28.9 0.0 8.4e-07 28.9 0.0 1.2 1 1 0 1 1 1 1 Endonuclease V TLD PF07534.16 CDS31397.1 - 2.6e-27 95.7 0.6 9.3e-27 93.9 0.6 1.8 1 1 0 1 1 1 1 TLD Med6 PF04934.14 CDS31398.1 - 3e-36 124.2 0.0 4e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component rve PF00665.26 CDS31399.1 - 6.1e-16 58.7 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS31399.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF3322 PF11795.8 CDS31399.1 - 0.16 11.9 0.1 0.68 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Laminin_G_3 PF13385.6 CDS31400.1 - 6.3e-09 36.2 3.7 0.00011 22.4 0.0 3.4 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 CDS31400.1 - 0.00013 22.6 0.0 1 9.9 0.0 4.2 4 0 0 4 4 4 1 Laminin G domain EGF PF00008.27 CDS31400.1 - 0.0052 17.1 6.4 0.0052 17.1 6.4 3.5 3 1 0 3 3 3 1 EGF-like domain Ski_Sno PF02437.17 CDS31401.1 - 4.8e-33 113.1 0.0 1.1e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 SKI/SNO/DAC family c-SKI_SMAD_bind PF08782.10 CDS31401.1 - 5.1e-26 90.7 3.2 5.1e-26 90.7 3.2 1.9 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Hormone_4 PF00220.17 CDS31401.1 - 0.14 12.2 0.3 0.36 10.9 0.3 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain SNF PF00209.18 CDS31402.2 - 1.6e-07 30.4 0.0 2.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Pkinase PF00069.25 CDS31405.2 - 3.8e-66 223.2 0.0 4.5e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31405.2 - 2.1e-25 89.5 0.0 2.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31405.2 - 3.4e-07 29.9 0.0 1.1e-05 24.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CDS31405.2 - 7.4e-05 22.8 0.4 0.0088 16.0 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS31405.2 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 CDS31405.2 - 0.15 12.2 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC1 family RVT_1 PF00078.27 CDS31407.1 - 2.2e-21 76.4 0.0 1e-12 48.1 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDS31407.1 - 7.9e-20 71.2 0.0 2.5e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDS31407.1 - 1.1e-18 67.2 1.3 9.1e-17 60.9 1.3 2.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS31407.1 - 1e-17 64.3 0.6 1.2e-16 60.8 0.6 2.5 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDS31407.1 - 4.6e-16 58.7 1.4 4.6e-16 58.7 1.4 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS31407.1 - 0.0036 17.5 0.1 0.0094 16.1 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDS31407.1 - 0.0095 15.7 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Ribosomal_S13 PF00416.22 CDS31408.1 - 5.3e-53 178.8 4.7 6.1e-53 178.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CDS31408.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CDS31408.1 - 0.044 14.0 0.2 0.16 12.3 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.9 CDS31408.1 - 0.067 13.6 1.3 0.13 12.7 1.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Sdh5 PF03937.16 CDS31408.1 - 0.17 11.8 0.9 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase RVT_1 PF00078.27 CDS31409.1 - 0.0043 16.6 0.1 0.0069 15.9 0.1 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDS31411.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CDS31412.1 - 0.0043 16.6 0.1 0.0069 15.9 0.1 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_2 PF13465.6 CDS31413.1 - 7.3e-31 105.2 35.7 1.1e-08 35.1 0.9 6.2 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS31413.1 - 8.1e-20 70.1 35.2 0.00027 21.2 0.2 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS31413.1 - 5.8e-15 54.7 33.2 0.0093 16.7 0.3 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS31413.1 - 8.8e-07 28.8 23.0 0.13 12.3 1.0 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 CDS31413.1 - 0.00019 21.7 22.2 0.055 13.9 0.8 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS31413.1 - 0.0049 17.1 13.1 0.45 10.9 0.1 4.7 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS31413.1 - 0.033 13.9 6.8 1.1 9.1 0.1 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDS31413.1 - 0.11 12.6 18.2 19 5.5 7.2 4.5 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 CDS31413.1 - 0.21 12.3 10.2 2.5 8.8 0.7 4.4 2 2 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 CDS31413.1 - 0.64 10.0 22.1 0.33 10.9 2.4 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 CDS31413.1 - 3.3 7.6 6.5 5.7 6.9 0.5 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 CDS31413.1 - 5.6 7.4 15.6 31 5.0 0.2 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) GDP_Man_Dehyd PF16363.5 CDS31414.1 - 2.8e-51 174.9 0.0 1.5e-50 172.5 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDS31414.1 - 5.3e-44 150.5 0.0 7.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDS31414.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDS31414.1 - 8.5e-09 34.9 0.0 0.0004 19.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 CDS31414.1 - 0.0004 19.6 0.0 0.007 15.5 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDS31414.1 - 0.00067 18.8 0.0 0.0026 16.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDS31414.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 CDS31414.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 CDS31414.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Ig_3 PF13927.6 CDS31416.1 - 1.4e-23 83.3 0.0 3.9e-10 40.2 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS31416.1 - 7.2e-20 70.9 0.0 1.4e-06 28.3 0.1 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain V-set PF07686.17 CDS31416.1 - 8.3e-16 58.1 0.0 1.6e-05 25.0 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.25 CDS31416.1 - 1.1e-15 57.5 0.4 5.9e-08 32.8 0.3 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CDS31416.1 - 3.1e-11 43.5 1.1 0.057 13.8 0.4 4.7 3 2 0 3 3 3 3 Immunoglobulin domain Izumo-Ig PF16706.5 CDS31416.1 - 0.00032 20.7 0.0 0.11 12.6 0.0 2.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 CDS31416.1 - 0.02 14.9 0.2 2.8 8.0 0.0 3.6 3 1 1 4 4 4 0 C17orf99 Ig domain Ig_6 PF18452.1 CDS31416.1 - 0.02 14.5 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain DUF1556 PF07590.11 CDS31416.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) ParA PF10609.9 CDS31418.1 - 3.3e-85 285.5 0.7 3.8e-85 285.3 0.7 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDS31418.1 - 3.6e-10 40.0 0.0 2e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDS31418.1 - 5.2e-06 26.5 0.3 1.2e-05 25.3 0.2 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CDS31418.1 - 0.00021 20.7 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CDS31418.1 - 0.00077 18.7 0.5 0.037 13.2 0.2 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CDS31418.1 - 0.0037 16.8 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 CDS31418.1 - 0.068 13.0 0.2 6 6.6 0.3 2.3 2 0 0 2 2 2 0 AAA domain VirC1 PF07015.11 CDS31418.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Methyltransf_23 PF13489.6 CDS31419.1 - 1.5e-19 70.5 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS31419.1 - 1.4e-17 64.1 0.0 2.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS31419.1 - 7.2e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS31419.1 - 2.2e-13 50.7 0.0 4.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS31419.1 - 2.4e-12 46.9 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CDS31419.1 - 2.5e-08 33.8 0.0 4.8e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 CDS31419.1 - 1.4e-06 28.0 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CDS31419.1 - 1.3e-05 24.6 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CDS31419.1 - 0.0062 15.9 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDS31419.1 - 0.0079 15.8 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CDS31419.1 - 0.035 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CDS31419.1 - 0.051 12.7 0.0 0.49 9.5 0.0 2.0 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.11 CDS31419.1 - 0.16 10.9 0.0 0.4 9.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PUA_3 PF17785.1 CDS31420.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 PUA-like domain Homeobox_KN PF05920.11 CDS31421.1 - 2.2e-11 43.4 0.2 5.9e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS31421.1 - 2e-06 27.5 0.1 4.4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CDS31421.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sds3 PF08598.11 CDS31422.1 - 3.4e-08 33.8 0.3 4.7e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 Sds3-like Glu_syn_central PF04898.14 CDS31422.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain Arm PF00514.23 CDS31423.2 - 8.7e-09 35.1 25.7 0.22 11.6 0.1 9.4 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 CDS31423.2 - 6e-08 32.6 0.1 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Atx10homo_assoc PF09759.9 CDS31423.2 - 9.6e-05 22.3 0.7 6.1 6.9 0.0 5.1 6 0 0 6 6 6 2 Spinocerebellar ataxia type 10 protein domain hnRNP_Q_AcD PF18360.1 CDS31423.2 - 0.00098 19.0 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain IF-2B PF01008.17 CDS31423.2 - 0.018 14.2 0.6 5.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Initiation factor 2 subunit family DHHC PF01529.20 CDS31423.2 - 0.081 13.0 6.2 3.9 7.6 0.6 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase SCAMP PF04144.13 CDS31424.1 - 1.8e-56 191.2 16.9 2.1e-56 191.0 16.9 1.1 1 0 0 1 1 1 1 SCAMP family Tweety PF04906.13 CDS31424.1 - 0.059 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Tweety Cbl_N3 PF02762.14 CDS31425.2 - 1.2e-31 108.4 1.0 2.4e-31 107.4 1.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain zf-C3HC4_3 PF13920.6 CDS31425.2 - 4.6e-05 23.2 4.4 9.5e-05 22.2 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS31425.2 - 0.00011 22.0 4.7 0.00028 20.7 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS31425.2 - 0.00028 20.7 5.3 0.0006 19.6 5.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 IFT57 PF10498.9 CDS31425.2 - 0.00045 19.3 1.3 0.00067 18.7 1.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GOLGA2L5 PF15070.6 CDS31425.2 - 0.0076 15.0 0.2 0.011 14.5 0.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 HTH_8 PF02954.19 CDS31425.2 - 0.014 15.2 0.2 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family YkyA PF10368.9 CDS31425.2 - 0.021 14.5 2.3 0.044 13.5 2.3 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein RasGAP_C PF03836.15 CDS31425.2 - 0.021 15.0 9.2 0.07 13.3 9.2 1.9 1 1 0 1 1 1 0 RasGAP C-terminus FapA PF03961.13 CDS31425.2 - 0.023 13.3 1.0 0.033 12.8 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_UBOX PF13445.6 CDS31425.2 - 0.038 14.0 3.3 0.11 12.5 3.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger PTPA PF03095.15 CDS31425.2 - 0.043 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Spc7 PF08317.11 CDS31425.2 - 0.053 12.4 2.2 0.082 11.8 2.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AATF-Che1 PF13339.6 CDS31425.2 - 0.067 13.9 2.0 0.15 12.7 2.0 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SesA PF17107.5 CDS31425.2 - 0.08 13.1 0.6 0.21 11.8 0.6 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ISG65-75 PF11727.8 CDS31425.2 - 0.088 12.0 0.7 0.14 11.4 0.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Prominin PF05478.11 CDS31425.2 - 0.14 10.1 1.8 0.23 9.4 1.8 1.2 1 0 0 1 1 1 0 Prominin HMMR_N PF15905.5 CDS31425.2 - 0.18 11.2 8.3 0.062 12.8 5.6 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3450 PF11932.8 CDS31425.2 - 0.3 10.3 1.4 0.53 9.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-K PF11802.8 CDS31425.2 - 1.9 8.0 9.5 0.16 11.5 4.6 1.6 2 0 0 2 2 2 0 Centromere-associated protein K Sec2p PF06428.11 CDS31425.2 - 3.4 7.7 8.6 1.4 9.0 4.4 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p XhlA PF10779.9 CDS31425.2 - 5 7.4 5.0 3 8.1 2.4 1.9 1 1 1 2 2 2 0 Haemolysin XhlA DUF1772 PF08592.11 CDS31426.1 - 0.014 15.7 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) FAM176 PF14851.6 CDS31426.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 FAM176 family LRR19-TM PF15176.6 CDS31426.1 - 0.045 13.7 0.3 0.093 12.7 0.3 1.6 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain YMF19 PF02326.15 CDS31426.1 - 0.11 13.3 0.0 0.16 12.8 0.0 1.2 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF2273 PF10031.9 CDS31426.1 - 2 8.5 8.3 16 5.6 0.2 2.1 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF1126 PF06565.12 CDS31427.1 - 3.3e-97 319.3 1.8 3.2e-34 116.9 0.1 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain CSRNP_N PF16019.5 CDS31428.1 - 5e-83 278.3 7.8 5e-83 278.3 7.8 1.9 2 0 0 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus Pro_isomerase PF00160.21 CDS31429.1 - 1.9e-44 151.7 0.5 2.5e-44 151.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP_synth_reg PF14960.6 CDS31429.1 - 1.5e-10 40.4 2.8 2.6e-10 39.6 2.8 1.4 1 0 0 1 1 1 1 ATP synthase regulation Ribosomal_L27A PF00828.19 CDS31430.1 - 1.4e-21 77.5 0.0 2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Serpin PF00079.20 CDS31431.1 - 0.0096 15.3 0.0 0.0099 15.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AD PF09793.9 CDS31432.1 - 1.3e-22 79.8 0.2 1.7e-22 79.3 0.2 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Viral_Rep PF02407.16 CDS31432.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative viral replication protein WD40 PF00400.32 CDS31433.1 - 3.1e-53 176.6 22.5 1.5e-08 35.1 0.1 9.5 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31433.1 - 1.7e-18 66.7 0.5 0.00048 20.4 0.0 6.4 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain SNARE_assoc PF09335.11 CDS31433.1 - 4.6e-14 52.9 5.9 9.8e-14 51.9 5.9 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein Ge1_WD40 PF16529.5 CDS31433.1 - 4e-08 32.6 0.0 0.036 13.0 0.0 3.8 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 CDS31433.1 - 5e-08 33.4 0.0 9.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain PD40 PF07676.12 CDS31433.1 - 0.00044 20.1 0.9 17 5.5 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CDS31433.1 - 0.0051 16.7 0.0 0.2 11.5 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 CDS31433.1 - 0.015 15.2 2.3 46 3.9 0.0 4.6 5 0 0 5 5 5 0 Transcription factor IIIC subunit delta N-term Nup160 PF11715.8 CDS31433.1 - 0.019 13.6 1.1 2.3 6.8 0.0 3.7 4 1 1 5 5 5 0 Nucleoporin Nup120/160 DUF4014 PF13198.6 CDS31433.1 - 0.74 10.2 3.3 27 5.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) NIF PF03031.18 CDS31434.1 - 1.9e-49 167.5 0.0 4.2e-49 166.3 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF4139 PF13598.6 CDS31434.1 - 0.032 14.0 0.3 0.054 13.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) RNase_P_Rpp14 PF01900.19 CDS31435.1 - 2e-17 63.3 0.3 4.3e-17 62.2 0.2 1.7 1 1 0 1 1 1 1 Rpp14/Pop5 family zf-C3HC4_3 PF13920.6 CDS31435.1 - 1.2e-09 37.9 5.7 2e-09 37.2 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS31435.1 - 7.9e-09 35.2 7.2 1.4e-08 34.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS31435.1 - 1.1e-08 35.2 9.0 2.3e-08 34.3 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDS31435.1 - 6.5e-08 32.3 6.7 1.1e-07 31.6 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDS31435.1 - 1.1e-07 31.6 8.8 1.9e-07 30.8 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS31435.1 - 1.3e-07 31.4 6.5 2.3e-07 30.6 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS31435.1 - 1.7e-07 31.1 1.7 1.7e-07 31.1 1.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS31435.1 - 0.00039 20.5 7.3 0.00039 20.5 7.3 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDS31435.1 - 0.00089 19.5 6.7 0.0017 18.6 6.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 CDS31435.1 - 0.0014 18.6 3.2 0.0027 17.6 3.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 CDS31435.1 - 0.0018 18.3 2.6 0.0036 17.3 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 CDS31435.1 - 0.023 14.1 0.2 0.034 13.5 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UDP PF14569.6 CDS31435.1 - 0.056 13.6 0.8 0.12 12.5 0.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 CDS31435.1 - 0.059 13.2 6.4 0.13 12.1 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CDS31435.1 - 0.11 12.2 3.3 0.31 10.8 3.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 CDS31435.1 - 0.44 10.8 7.2 0.9 9.8 5.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TerY_C PF15616.6 CDS31435.1 - 0.45 10.6 3.1 0.86 9.7 3.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 CDS31435.1 - 0.53 10.4 3.5 1.2 9.4 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 CDS31435.1 - 1.1 8.9 7.0 2.6 7.8 7.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HLH PF00010.26 CDS31436.1 - 0.00027 20.8 0.1 0.00055 19.8 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CDS31436.1 - 0.00038 20.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 CDS31436.1 - 0.0041 17.4 0.0 0.7 10.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CDS31436.1 - 0.012 15.9 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain DUF1573 PF07610.11 CDS31436.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Tetraspanin PF00335.20 CDS31438.1 - 2.1e-23 83.2 11.4 3.2e-23 82.6 11.4 1.2 1 1 0 1 1 1 1 Tetraspanin family MgtE PF01769.16 CDS31438.1 - 0.11 12.8 7.4 0.77 10.2 5.8 2.2 2 0 0 2 2 2 0 Divalent cation transporter TssN PF17555.2 CDS31438.1 - 9.2 5.6 11.3 1.6 8.0 7.8 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN Tetraspanin PF00335.20 CDS31439.1 - 1e-33 116.9 14.9 1.2e-33 116.8 14.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 CDS31439.1 - 0.0037 17.3 2.0 0.0037 17.3 2.0 3.0 2 1 1 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2723 PF11028.8 CDS31439.1 - 0.78 9.6 8.0 0.15 12.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Cadherin PF00028.17 CDS31442.1 - 1e-61 205.4 5.1 6.5e-17 61.8 0.1 8.3 7 1 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS31442.1 - 1.4e-12 47.3 0.3 1.1e-08 34.8 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CDS31442.1 - 2.5e-05 24.2 7.2 0.43 10.6 0.0 5.4 4 1 1 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 CDS31442.1 - 0.0026 18.1 0.0 2.2 8.6 0.0 3.3 3 0 0 3 3 3 2 RET Cadherin like domain 1 Orai-1 PF07856.12 CDS31444.1 - 6.5e-57 192.0 9.0 9.5e-57 191.5 9.0 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Pyr_redox_2 PF07992.14 CDS31444.1 - 3.9e-18 65.7 0.0 1e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 CDS31444.1 - 4e-05 23.5 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 CDS31444.1 - 0.0058 17.2 1.3 2.7 8.6 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDS31444.1 - 0.015 14.4 0.9 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DUF2207 PF09972.9 CDS31444.1 - 0.016 14.0 1.2 0.027 13.2 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NAD_binding_9 PF13454.6 CDS31444.1 - 0.037 14.0 0.0 3.5 7.6 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CDS31444.1 - 0.086 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1129 PF06570.11 CDS31444.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Orai-1 PF07856.12 CDS31445.1 - 8.4e-58 194.9 8.0 1e-57 194.6 8.0 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF1129 PF06570.11 CDS31445.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF4083 PF13314.6 CDS31445.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF4579 PF15158.6 CDS31445.1 - 0.19 11.5 3.2 0.34 10.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) Phage_holin_3_6 PF07332.11 CDS31445.1 - 0.57 10.2 10.9 0.11 12.5 1.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III FtsX PF02687.21 CDS31445.1 - 2.6 8.6 12.0 0.22 12.0 5.8 2.3 1 1 1 2 2 2 0 FtsX-like permease family DUF4191 PF13829.6 CDS31445.1 - 2.7 7.3 5.0 0.62 9.4 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) OCRE PF17780.1 CDS31446.1 - 9.3e-17 60.8 14.8 1.8e-16 59.9 14.8 1.5 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 CDS31446.1 - 1.9e-13 50.1 1.7 4.3e-13 48.9 1.7 1.6 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 CDS31446.1 - 1.3e-11 44.6 0.1 1.3e-11 44.6 0.1 2.2 2 1 0 2 2 2 1 FHA domain G-patch_2 PF12656.7 CDS31446.1 - 4.1e-06 26.8 0.6 1.2e-05 25.3 0.6 1.8 1 0 0 1 1 1 1 G-patch domain UPF0242 PF06785.11 CDS31446.1 - 0.34 11.0 3.2 0.87 9.7 3.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Myotub-related PF06602.14 CDS31447.1 - 1.6e-118 395.7 0.3 2.5e-118 395.0 0.3 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CDS31447.1 - 0.0023 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4140 PF13600.6 CDS31447.1 - 0.012 16.0 0.2 0.044 14.2 0.2 1.9 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Y_phosphatase3 PF13350.6 CDS31447.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ABC_tran_CTD PF16326.5 CDS31447.1 - 0.034 14.4 1.1 6.2 7.2 1.9 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain YlqD PF11068.8 CDS31447.1 - 0.069 13.5 0.8 0.15 12.5 0.8 1.5 1 0 0 1 1 1 0 YlqD protein Y_phosphatase PF00102.27 CDS31447.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DivIC PF04977.15 CDS31447.1 - 0.92 9.3 8.6 0.25 11.1 5.0 1.9 2 0 0 2 2 2 0 Septum formation initiator CASP_C PF08172.12 CDS31447.1 - 7.6 5.8 10.6 0.19 11.0 0.7 2.4 2 0 0 2 2 2 0 CASP C terminal Ribosomal_L28 PF00830.19 CDS31448.1 - 0.028 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L28 family HARE-HTH PF05066.13 CDS31448.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Tetraspanin PF00335.20 CDS31450.1 - 1.2e-18 67.7 14.7 1.5e-18 67.4 14.7 1.1 1 0 0 1 1 1 1 Tetraspanin family VIT1 PF01988.19 CDS31450.1 - 0.00062 19.7 2.7 0.001 19.0 2.7 1.4 1 0 0 1 1 1 1 VIT family 5TM-5TMR_LYT PF07694.12 CDS31450.1 - 0.0039 16.7 4.6 0.025 14.1 1.1 2.3 2 0 0 2 2 2 1 5TMR of 5TMR-LYT DUF3377 PF11857.8 CDS31450.1 - 0.12 12.3 6.7 1.7 8.6 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Ninjurin PF04923.12 CDS31450.1 - 0.16 11.9 3.4 0.46 10.5 0.6 2.5 2 1 0 2 2 2 0 Ninjurin JSRP PF15312.6 CDS31450.1 - 0.43 10.5 2.0 24 4.9 0.8 2.4 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF4199 PF13858.6 CDS31450.1 - 0.8 10.1 7.7 1 9.7 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ABC2_membrane_3 PF12698.7 CDS31450.1 - 3.1 6.8 14.9 1 8.4 10.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein TMEM220 PF15071.6 CDS31451.2 - 0.95 10.3 5.0 0.54 11.0 0.4 2.1 1 1 1 2 2 2 0 Transmembrane family 220, helix DUF373 PF04123.13 CDS31451.2 - 2.5 7.5 6.3 2.8 7.3 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ig_3 PF13927.6 CDS31452.1 - 6.3e-07 29.9 5.1 9.1 7.0 0.0 7.7 8 0 0 8 8 8 3 Immunoglobulin domain V-set PF07686.17 CDS31452.1 - 0.0025 17.9 0.0 3 8.0 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.6 CDS31452.1 - 0.013 15.9 4.7 42 4.6 0.0 5.4 5 0 0 5 5 5 0 Immunoglobulin domain Pkinase PF00069.25 CDS31453.1 - 2.8e-66 223.6 0.0 3.9e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31453.1 - 1.9e-31 109.3 0.0 2.8e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31453.1 - 3.6e-06 26.5 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDS31453.1 - 0.0011 18.0 0.0 0.0026 16.8 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS31453.1 - 0.016 14.5 0.1 0.049 13.0 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IL1 PF00340.19 CDS31453.1 - 0.018 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Interleukin-1 / 18 APH PF01636.23 CDS31453.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CDS31453.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL LEDGF PF11467.8 CDS31454.1 - 2.4e-11 43.3 0.5 4.5e-11 42.4 0.5 1.4 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.17 CDS31454.1 - 3e-08 33.9 0.8 7.2e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 PWWP domain Fz PF01392.22 CDS31455.1 - 1.4e-17 64.3 6.1 1.4e-17 64.3 6.1 2.0 1 1 1 2 2 2 1 Fz domain Beach PF02138.18 CDS31456.2 - 7.1e-120 399.5 0.0 1.6e-119 398.4 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CDS31456.2 - 2.5e-16 59.6 0.0 7.6e-16 58.1 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CDS31456.2 - 1.5e-12 47.4 0.3 3e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) DUF4800 PF16057.5 CDS31456.2 - 8.4e-11 41.6 1.7 2.4e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4800) WD40 PF00400.32 CDS31456.2 - 0.0036 18.1 0.3 0.066 14.1 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-AN1 PF01428.16 CDS31457.1 - 1.4e-09 37.9 6.6 1.4e-09 37.9 6.6 2.4 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.16 CDS31457.1 - 4.7e-08 32.8 4.2 4.7e-08 32.8 4.2 1.9 2 0 0 2 2 2 1 A20-like zinc finger Ornatin PF02088.15 CDS31457.1 - 0.13 12.1 3.2 1.3 8.8 0.8 2.4 1 1 1 2 2 2 0 Ornatin TLD PF07534.16 CDS31458.1 - 1.5e-23 83.6 0.2 3.3e-20 72.7 0.0 3.8 2 1 1 3 3 3 2 TLD LysM PF01476.20 CDS31458.1 - 6.2e-09 35.8 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain RP-C PF03428.13 CDS31458.1 - 0.19 11.4 0.0 14 5.2 0.0 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain Alpha_Helical PF18489.1 CDS31460.1 - 0.0069 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha helical domain Thioredoxin PF00085.20 CDS31461.1 - 8.2e-56 186.4 0.5 7.7e-27 93.3 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDS31461.1 - 9.3e-23 81.1 2.6 2.5e-12 47.1 0.7 3.7 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CDS31461.1 - 2.2e-07 31.1 0.1 0.024 14.9 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDS31461.1 - 6.8e-06 26.5 0.9 0.11 13.0 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CDS31461.1 - 1.2e-05 25.2 0.2 0.017 15.0 0.1 2.7 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CDS31461.1 - 1.8e-05 24.8 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 CDS31461.1 - 0.00048 19.9 0.3 0.013 15.2 0.0 2.7 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.6 CDS31461.1 - 0.0019 18.4 1.8 0.35 11.0 0.1 3.6 3 1 1 4 4 4 1 Thioredoxin OST3_OST6 PF04756.13 CDS31461.1 - 0.018 14.4 0.1 0.21 10.9 0.0 2.7 2 2 2 4 4 4 0 OST3 / OST6 family, transporter family ParD PF09386.10 CDS31461.1 - 0.059 13.8 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Antitoxin ParD Endonuclease_5 PF04493.14 CDS31469.2 - 7.3e-30 104.1 0.0 9.2e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V TPR_8 PF13181.6 CDS31471.1 - 4.9e-10 38.8 0.1 2.5 8.5 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS31471.1 - 7.7e-09 35.9 5.0 0.028 14.9 0.0 5.7 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS31471.1 - 1.5e-08 35.1 1.0 0.071 13.8 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31471.1 - 1.5e-06 27.8 1.2 4.3 7.6 0.0 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS31471.1 - 2.8e-05 23.8 4.3 1.6 8.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDS31471.1 - 0.00017 20.9 0.8 0.0068 15.6 0.2 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31471.1 - 0.00032 21.3 9.5 30 5.8 0.1 7.2 4 2 4 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDS31471.1 - 0.0006 20.0 8.4 0.13 12.7 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31471.1 - 0.0016 18.7 12.4 0.043 14.1 0.5 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDS31471.1 - 0.046 14.4 2.7 1.1 10.0 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 CDS31471.1 - 0.095 12.9 0.3 17 5.7 0.1 3.2 3 1 1 4 4 4 0 Tetratrico peptide repeat TPR_6 PF13174.6 CDS31471.1 - 0.11 13.2 0.1 3.4e+02 2.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS31471.1 - 0.2 11.8 11.2 34 4.9 0.0 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS31471.1 - 0.29 11.1 6.9 7.6 6.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Trypsin PF00089.26 CDS31472.1 - 2.8e-33 115.6 0.4 1.9e-31 109.6 0.4 2.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDS31472.1 - 0.00021 22.2 0.0 0.00037 21.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain TSP_1 PF00090.19 CDS31472.1 - 0.011 15.9 1.8 0.011 15.9 1.8 2.5 2 0 0 2 2 2 0 Thrombospondin type 1 domain zf-C2H2 PF00096.26 CDS31474.2 - 5.7e-06 26.5 1.0 0.00028 21.2 0.1 3.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CDS31474.2 - 0.066 13.6 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDS31474.2 - 0.23 12.4 0.2 0.23 12.4 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS31476.2 - 0.00012 22.4 27.7 0.00035 20.8 0.1 5.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31476.2 - 0.00093 19.5 15.3 0.4 11.2 1.9 5.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31476.2 - 0.29 12.1 0.2 0.29 12.1 0.2 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger DUF3932 PF13068.6 CDS31479.2 - 0.35 11.2 5.9 0.095 13.0 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) HTH_20 PF12840.7 CDS31483.2 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain IER PF05760.12 CDS31487.1 - 0.18 12.1 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Atg8 PF02991.16 CDS31488.1 - 3.1e-45 152.6 0.0 3.6e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CDS31488.1 - 3.6e-08 33.7 0.0 4.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 zf-C2H2 PF00096.26 CDS31490.1 - 6.9e-17 60.9 23.2 1.5e-07 31.5 2.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS31490.1 - 2.9e-15 55.9 20.5 3.1e-08 33.7 2.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31490.1 - 2.6e-13 49.6 19.9 1.6e-05 25.3 1.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS31490.1 - 1.4e-06 28.1 14.0 0.0032 17.4 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 CDS31490.1 - 8.3e-06 25.7 13.6 0.12 12.4 0.3 3.6 2 1 1 3 3 3 2 BED zinc finger zf-C2H2_jaz PF12171.8 CDS31490.1 - 2e-05 24.7 4.5 0.013 15.7 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CDS31490.1 - 0.00043 20.0 17.5 0.045 13.5 1.3 3.6 1 1 2 3 3 3 2 GAGA factor zf-Di19 PF05605.12 CDS31490.1 - 0.00051 20.3 9.7 0.012 15.9 5.1 2.3 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 CDS31490.1 - 0.0012 18.4 8.0 0.53 9.9 0.4 3.6 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 CDS31490.1 - 0.0019 18.5 11.7 0.019 15.4 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 CDS31490.1 - 0.0021 17.6 1.7 0.41 10.3 0.1 2.9 2 1 1 3 3 3 1 MYST family zinc finger domain zinc_ribbon_15 PF17032.5 CDS31490.1 - 0.0028 18.4 3.4 0.019 15.7 1.4 2.3 1 1 2 3 3 3 2 zinc-ribbon family zf-C2H2_11 PF16622.5 CDS31490.1 - 0.0039 16.9 20.3 0.66 9.8 1.2 3.6 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CDS31490.1 - 0.0046 17.3 7.3 2.1 8.8 0.1 3.3 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 CDS31490.1 - 0.012 15.8 6.5 8.8 6.6 0.1 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger Elf1 PF05129.13 CDS31490.1 - 0.013 15.5 4.8 1.2 9.2 0.1 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 CDS31490.1 - 0.017 15.3 7.1 0.25 11.6 2.8 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2HE PF16278.5 CDS31490.1 - 0.018 15.5 10.8 0.64 10.5 0.4 3.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CDS31490.1 - 0.025 14.3 34.1 0.59 9.9 7.9 5.0 3 3 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 CDS31490.1 - 0.029 14.5 5.2 6.7 6.9 2.5 3.0 2 1 1 3 3 3 0 Zinc ribbon domain PHD_Oberon PF07227.11 CDS31490.1 - 0.034 14.0 1.8 0.052 13.4 1.8 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-WRNIP1_ubi PF18279.1 CDS31490.1 - 0.044 14.4 0.2 0.12 13.1 0.2 1.7 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain C1_1 PF00130.22 CDS31490.1 - 0.049 13.5 4.5 0.068 13.1 1.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2256 PF10013.9 CDS31490.1 - 0.079 13.1 4.8 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1180 PF06679.12 CDS31490.1 - 0.11 12.9 0.8 0.14 12.5 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) zf-C2H2_3rep PF18868.1 CDS31490.1 - 0.13 12.9 6.0 14 6.4 6.9 3.0 2 1 2 4 4 3 0 Zinc finger C2H2-type, 3 repeats OrsD PF12013.8 CDS31490.1 - 0.14 12.6 11.5 1 9.8 0.3 3.3 1 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D ADK_lid PF05191.14 CDS31490.1 - 0.19 11.7 2.0 4.4 7.4 0.1 2.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 CDS31490.1 - 0.19 12.0 7.1 8.7 6.7 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbon Trm112p PF03966.16 CDS31490.1 - 0.35 11.5 3.2 11 6.6 3.2 3.1 1 1 0 1 1 1 0 Trm112p-like protein Nudix_N_2 PF14803.6 CDS31490.1 - 0.38 10.7 4.1 2 8.4 0.0 3.0 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_10 PF10058.9 CDS31490.1 - 0.47 10.2 6.8 3.8 7.3 0.1 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 CDS31490.1 - 0.48 10.4 8.9 1.5 8.8 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-HIT PF04438.16 CDS31490.1 - 0.48 10.3 9.5 6.1 6.8 0.3 3.3 3 0 0 3 3 3 0 HIT zinc finger zf-C2HC_2 PF13913.6 CDS31490.1 - 0.52 10.3 13.3 1.5 8.8 1.1 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHY PF05495.12 CDS31490.1 - 0.67 10.5 11.3 0.28 11.7 3.9 2.5 1 1 1 2 2 2 0 CHY zinc finger A2L_zn_ribbon PF08792.10 CDS31490.1 - 0.73 9.6 4.4 6.7 6.6 0.0 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 CDS31490.1 - 0.78 9.8 5.6 13 5.9 5.6 2.6 1 1 0 1 1 1 0 zinc-ribbons PHD PF00628.29 CDS31490.1 - 0.99 9.4 5.6 10 6.1 0.1 3.0 2 1 1 3 3 3 0 PHD-finger Actin_micro PF17003.5 CDS31490.1 - 1.1 8.4 5.0 1.7 7.8 3.5 2.0 1 1 0 1 1 1 0 Putative actin-like family zf-UBP PF02148.19 CDS31490.1 - 1.1 9.6 8.9 2.4e+02 2.2 9.2 2.5 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_ribbon_SprT PF17283.2 CDS31490.1 - 1.3 9.0 12.6 0.45 10.5 8.8 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 CDS31490.1 - 1.8 8.6 7.6 17 5.5 7.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 CDS31490.1 - 1.9 8.5 12.7 7.6 6.6 8.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.6 CDS31490.1 - 2.1 8.4 7.2 22 5.1 0.1 3.1 2 1 0 2 2 2 0 zinc-RING finger domain IBR PF01485.21 CDS31490.1 - 3.3 8.0 8.1 15 5.9 8.1 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ribosomal_L37ae PF01780.19 CDS31490.1 - 3.6 7.7 6.0 39 4.4 0.0 3.0 2 1 0 2 2 2 0 Ribosomal L37ae protein family Isy1 PF06246.12 CDS31491.1 - 2.5e-86 289.4 8.7 6.2e-86 288.1 8.7 1.6 1 1 0 1 1 1 1 Isy1-like splicing family Radical_SAM PF04055.21 CDS31491.1 - 0.029 14.7 0.6 0.11 12.9 0.1 2.1 2 1 0 2 2 2 0 Radical SAM superfamily Astro_capsid_p PF12226.8 CDS31491.1 - 1 8.4 6.4 0.8 8.8 0.3 2.1 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Septin PF00735.18 CDS31492.1 - 2.6e-84 282.8 0.0 6.4e-84 281.6 0.0 1.6 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CDS31492.1 - 2.9e-06 27.3 0.0 7.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase HAUS6_N PF14661.6 CDS31492.1 - 0.0057 16.3 4.9 0.01 15.4 4.9 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Transposase_24 PF03004.14 CDS31492.1 - 0.0067 16.5 0.3 0.0067 16.5 0.3 2.5 3 0 0 3 3 3 1 Plant transposase (Ptta/En/Spm family) FtsK_SpoIIIE PF01580.18 CDS31492.1 - 0.011 15.1 2.4 0.015 14.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CDS31492.1 - 0.014 15.3 0.3 0.073 13.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 CDS31492.1 - 0.04 13.2 0.5 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Guanylate_kin PF00625.21 CDS31492.1 - 0.046 13.4 1.9 2 8.0 1.4 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_7 PF12775.7 CDS31492.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CDS31492.1 - 0.068 13.7 0.1 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CDS31492.1 - 0.072 13.4 0.2 0.32 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain Seryl_tRNA_N PF02403.22 CDS31492.1 - 0.075 13.3 4.5 0.24 11.6 4.5 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Dynamin_N PF00350.23 CDS31492.1 - 0.23 11.5 5.6 0.48 10.5 0.0 3.5 3 1 1 4 4 4 0 Dynamin family FUSC PF04632.12 CDS31492.1 - 0.3 9.6 4.7 0.4 9.2 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LemA PF04011.12 CDS31492.1 - 0.34 10.8 5.5 1 9.2 2.3 2.5 2 0 0 2 2 2 0 LemA family Fez1 PF06818.15 CDS31492.1 - 0.48 10.8 14.8 0.035 14.6 9.0 1.9 2 0 0 2 2 2 0 Fez1 DUF87 PF01935.17 CDS31492.1 - 1.7 8.7 7.7 5 7.1 1.6 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain UPF0242 PF06785.11 CDS31492.1 - 2 8.5 9.1 4.7 7.3 9.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CDS31492.1 - 2.1 7.8 7.7 0.9 9.0 4.6 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cir_N PF10197.9 CDS31492.1 - 7 6.9 8.3 20 5.5 8.3 1.8 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF4284 PF14112.6 CDS31494.1 - 0.11 13.4 0.0 0.3 12.0 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 22 FDF PF09532.10 CDS31496.1 - 2.3 9.1 6.4 2.3 9.2 0.5 2.8 2 0 0 2 2 2 0 FDF domain Col_cuticle_N PF01484.17 CDS31497.1 - 0.28 11.3 0.3 0.43 10.7 0.3 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain zf-C3HC4_3 PF13920.6 CDS31498.1 - 3.7e-09 36.3 11.1 3.7e-09 36.3 11.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS31498.1 - 1.9e-05 24.9 13.2 5.3e-05 23.5 13.2 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDS31498.1 - 0.0008 19.2 12.3 0.002 17.9 12.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CDS31498.1 - 0.0033 17.2 12.1 0.0089 15.9 12.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YPEB PF14620.6 CDS31498.1 - 0.01 15.2 2.1 0.01 15.2 2.1 1.9 2 0 0 2 2 2 0 YpeB sporulation AAA_13 PF13166.6 CDS31498.1 - 0.25 9.9 10.1 0.044 12.4 2.7 2.1 2 0 0 2 2 2 0 AAA domain BRE1 PF08647.11 CDS31498.1 - 0.38 10.9 13.8 2.7 8.1 1.2 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 CDS31498.1 - 0.51 10.4 7.9 1.3 9.1 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HCMV_UL139 PF12507.8 CDS31498.1 - 0.65 10.4 10.2 1.3 9.4 5.5 3.2 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein LptF_LptG PF03739.14 CDS31498.1 - 1 8.1 3.4 2.9 6.6 1.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG HMMR_N PF15905.5 CDS31498.1 - 5.4 6.4 20.1 5.3 6.4 3.6 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal V_ATPase_I PF01496.19 CDS31501.1 - 0.15 10.0 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2897 PF11446.8 CDS31501.1 - 1.6 8.7 3.6 2.9 7.8 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) LRR_9 PF14580.6 CDS31508.2 - 2.5e-20 72.7 6.0 4.7e-10 39.2 3.2 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 CDS31508.2 - 3.2e-12 46.5 25.0 1.1e-06 28.9 4.4 4.6 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS31508.2 - 3.1e-10 39.7 26.1 1.2e-06 28.1 8.7 4.2 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 CDS31508.2 - 0.0026 17.7 24.3 2 8.7 1.1 6.3 6 1 1 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 CDS31508.2 - 8.6 7.4 26.0 0.43 11.3 0.5 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 CDS31509.1 - 7.1e-17 60.0 21.3 8.3e-05 22.3 0.2 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 CDS31509.1 - 4.3e-11 42.9 10.8 0.017 15.5 0.8 6.1 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS31509.1 - 0.00038 20.6 7.9 1.2 9.9 0.1 6.7 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 CDS31509.1 - 0.0013 18.5 19.5 0.06 13.1 3.4 5.7 4 3 2 6 6 6 3 Leucine rich repeat E3_UbLigase_R4 PF13764.6 CDS31510.2 - 2e-118 396.8 0.1 3.3e-67 227.4 0.0 2.5 2 0 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 zf-UBR PF02207.20 CDS31510.2 - 0.00095 19.3 14.4 0.00095 19.3 14.4 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Suv3_N PF18114.1 CDS31510.2 - 0.1 12.7 0.1 79 3.4 0.0 3.6 3 0 0 3 3 3 0 Suv3 helical N-terminal domain Utp14 PF04615.13 CDS31510.2 - 5 5.6 20.0 0.019 13.6 9.6 1.9 1 1 1 2 2 2 0 Utp14 protein Baculo_ME53 PF06061.11 CDS31510.2 - 6.7 5.8 6.2 0.78 8.9 1.5 1.7 2 0 0 2 2 2 0 Baculoviridae ME53 Peptidase_C65 PF10275.9 CDS31512.2 - 5.3e-58 196.4 0.2 9.8e-56 188.9 0.2 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CDS31512.2 - 1.6e-05 25.4 0.1 7.9e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease ADP_PFK_GK PF04587.15 CDS31513.2 - 5.5e-104 348.1 0.0 6.1e-103 344.7 0.0 2.0 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region LIM PF00412.22 CDS31513.2 - 4.4e-12 46.0 5.3 7.7e-12 45.3 5.3 1.4 1 0 0 1 1 1 1 LIM domain WD40 PF00400.32 CDS31514.2 - 0.0017 19.2 0.1 0.18 12.8 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat NUFIP1 PF10453.9 CDS31515.1 - 0.00045 20.0 2.6 0.00045 20.0 2.6 2.8 4 0 0 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sec8_exocyst PF04048.14 CDS31516.2 - 0.0096 15.8 5.2 0.0096 15.8 5.2 4.3 5 0 0 5 5 5 1 Sec8 exocyst complex component specific domain Ponericin PF07442.11 CDS31516.2 - 0.079 13.0 1.2 14 5.9 0.1 2.3 2 0 0 2 2 2 0 Ponericin Methyltransf_25 PF13649.6 CDS31516.2 - 0.19 12.4 0.3 5 7.9 0.0 3.3 4 0 0 4 4 4 0 Methyltransferase domain DUF489 PF04356.12 CDS31516.2 - 5.8 6.9 17.2 1.7 8.6 3.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Ribosomal_S18 PF01084.20 CDS31519.2 - 2.2e-12 47.0 0.0 1.3e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S18 GST_N PF02798.20 CDS31521.1 - 3.4e-17 62.5 0.0 5.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDS31521.1 - 5.1e-15 55.5 0.0 9.4e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS31521.1 - 1.2e-12 47.8 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDS31521.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS31521.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDS31521.1 - 0.067 13.0 0.1 0.52 10.2 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS31522.1 - 7.1e-17 61.5 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDS31522.1 - 1.5e-15 57.2 0.3 2.8e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS31522.1 - 9.9e-13 48.1 0.1 1.6e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDS31522.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS31522.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rotavirus_VP1 PF12289.8 CDS31522.1 - 0.056 12.5 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain GST_N PF02798.20 CDS31524.1 - 9.7e-09 35.5 0.2 3.4e-07 30.5 0.2 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDS31524.1 - 3.4e-08 33.6 0.0 6.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS31524.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MA3 PF02847.17 CDS31525.1 - 0.0082 16.1 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 MA3 domain GST_N PF02798.20 CDS31526.1 - 1.9e-16 60.1 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDS31526.1 - 6.3e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDS31527.1 - 1.8e-15 56.9 0.3 2.9e-15 56.3 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS31527.1 - 8.2e-11 42.0 0.1 1.3e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS31527.1 - 2.4e-10 40.6 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS31527.1 - 0.00012 22.1 0.2 0.00066 19.7 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Ribosomal_L27A PF00828.19 CDS31529.1 - 9.3e-12 45.7 0.0 1.3e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L PF01193.24 CDS31531.1 - 3e-22 77.8 0.0 3.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 CDS31531.1 - 1.5e-21 75.9 0.0 6e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CDS31531.1 - 1.6e-17 63.9 0.0 3.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain DUF22 PF01629.16 CDS31531.1 - 0.19 11.4 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 Tubulin PF00091.25 CDS31533.1 - 8e-69 231.8 0.0 3.3e-68 229.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS31533.1 - 1.6e-40 138.2 0.0 2.4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS31533.1 - 9.3e-07 29.2 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS31533.1 - 0.029 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CDS31533.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin like ART PF01129.18 CDS31533.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Tubulin PF00091.25 CDS31534.1 - 3.3e-70 236.3 0.0 1.3e-69 234.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS31534.1 - 2.5e-40 137.5 0.0 3.8e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS31534.1 - 5.7e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS31534.1 - 0.0099 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS31534.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like ART PF01129.18 CDS31534.1 - 0.049 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase SH3BGR PF04908.15 CDS31535.2 - 3.7e-12 46.3 0.1 3.7e-12 46.3 0.1 3.0 2 2 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF1462 PF07315.11 CDS31535.2 - 0.00011 22.4 0.1 0.00029 21.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1462) MFS_1 PF07690.16 CDS31536.2 - 2e-24 86.2 45.7 4.8e-13 48.8 13.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 CDS31536.2 - 0.0087 15.6 9.5 0.028 13.9 0.2 3.0 3 0 0 3 3 3 2 Nodulin-like DUF3099 PF11298.8 CDS31536.2 - 0.018 15.1 0.0 14 5.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) TetR_C_16 PF17920.1 CDS31536.2 - 0.064 13.5 0.0 20 5.4 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 CDS31538.2 - 2.2e-05 23.6 1.5 2.3e-05 23.5 1.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 CDS31539.2 - 4.5e-22 78.4 50.9 1.6e-12 47.0 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CTU2 PF10288.9 CDS31542.2 - 1.1e-09 38.5 0.7 2e-09 37.7 0.7 1.5 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 CDS31542.2 - 0.0028 17.4 0.0 0.0069 16.2 0.0 1.6 1 1 0 1 1 1 1 PP-loop family SDF PF00375.18 CDS31543.1 - 1.9e-128 428.8 36.5 2.7e-128 428.3 36.5 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family KH_1 PF00013.29 CDS31544.2 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 KH domain Cyclin_N PF00134.23 CDS31545.1 - 0.083 12.6 0.6 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain Sld5 PF05916.11 CDS31546.2 - 0.00056 20.3 0.0 0.0008 19.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Spore_III_AB PF09548.10 CDS31546.2 - 0.042 14.0 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PH PF00169.29 CDS31547.2 - 8.3e-14 52.0 0.0 1.7e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 PH domain START PF01852.19 CDS31547.2 - 1e-11 44.7 0.6 2.5e-10 40.1 0.6 2.3 1 1 0 1 1 1 1 START domain PH_8 PF15409.6 CDS31547.2 - 1.6e-06 28.3 0.0 5.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CDS31547.2 - 0.00016 22.1 0.1 0.00083 19.8 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain BLOC1_2 PF10046.9 CDS31547.2 - 0.019 15.3 0.6 0.057 13.7 0.6 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRAF_BIRC3_bd PF16673.5 CDS31547.2 - 3 7.7 4.6 0.91 9.4 0.7 2.0 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Metallophos PF00149.28 CDS31548.1 - 5.2e-38 131.6 0.1 6.5e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDS31548.1 - 4.2e-21 75.1 1.0 6.7e-21 74.5 0.4 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Laminin_G_2 PF02210.24 CDS31549.1 - 8.1e-49 165.4 4.7 1.2e-16 61.5 0.0 5.6 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.23 CDS31549.1 - 1.5e-38 131.9 0.5 6.1e-16 58.8 0.0 5.7 6 0 0 6 6 6 4 Laminin G domain Laminin_G_3 PF13385.6 CDS31549.1 - 0.025 14.7 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily DUF4165 PF13752.6 CDS31549.1 - 0.16 12.0 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) hEGF PF12661.7 CDS31549.1 - 1.5 9.6 14.0 2.3 9.0 6.4 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 CDS31549.1 - 4.2 7.8 21.7 0.2 12.0 0.9 3.0 3 0 0 3 3 3 0 EGF-like domain LIM PF00412.22 CDS31550.1 - 4e-16 59.0 19.3 1.7e-09 37.8 0.8 3.0 2 1 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDS31550.1 - 8.3e-15 54.4 3.5 1.3e-14 53.8 3.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS31550.1 - 0.00056 19.8 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Homeobox KN domain DUF2175 PF09943.9 CDS31550.1 - 0.011 15.9 0.4 0.38 11.1 0.0 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2685 PF10886.8 CDS31550.1 - 1.1 9.5 5.5 0.26 11.5 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) tRNA_m1G_MT PF01746.21 CDS31551.1 - 2.6e-17 63.2 0.0 7.3e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Plectin PF00681.20 CDS31551.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat YqfQ PF14181.6 CDS31551.1 - 0.99 9.6 5.2 13 6.0 0.0 2.3 2 0 0 2 2 2 0 YqfQ-like protein CDC45 PF02724.14 CDS31551.1 - 1.4 7.1 5.7 1.9 6.7 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltr_RsmB-F PF01189.17 CDS31552.1 - 6.7e-19 68.3 1.2 5.7e-18 65.3 0.1 2.5 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDS31552.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase tRNA-synt_2b PF00587.25 CDS31553.1 - 3.8e-33 114.9 0.0 7.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDS31553.1 - 9.1e-22 77.0 0.3 2.1e-21 75.9 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CDS31553.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CDS31553.1 - 1e-09 38.3 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MAP65_ASE1 PF03999.12 CDS31554.1 - 5.8e-39 134.3 21.8 7.2e-39 134.0 21.8 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) L27_2 PF09045.10 CDS31554.1 - 0.062 13.3 3.1 0.15 12.1 0.1 2.9 3 0 0 3 3 3 0 L27_2 Cob_adeno_trans PF01923.18 CDS31554.1 - 1.5 8.9 9.2 1.7 8.7 0.4 4.0 2 2 2 4 4 4 0 Cobalamin adenosyltransferase COG5 PF10392.9 CDS31554.1 - 2.6 8.2 8.4 1.4 9.1 1.3 3.6 3 2 0 3 3 3 0 Golgi transport complex subunit 5 Sec34 PF04136.15 CDS31554.1 - 6.4 6.6 14.9 1.5 8.7 0.6 4.4 3 2 2 6 6 6 0 Sec34-like family Bacillus_HBL PF05791.11 CDS31554.1 - 7.3 6.4 11.4 1.7 8.5 2.5 3.1 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CAP PF00188.26 CDS31555.1 - 1.1e-25 90.9 1.4 4.6e-21 76.0 0.2 3.0 3 1 0 3 3 3 2 Cysteine-rich secretory protein family Methyltrn_RNA_2 PF04013.12 CDS31555.1 - 0.19 11.4 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase PTB PF08416.13 CDS31556.2 - 1.3e-13 51.3 0.0 3.2e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Phosphotyrosine-binding domain Trm112p PF03966.16 CDS31556.2 - 5.8e-12 46.0 0.0 1.1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Trm112p-like protein SH2 PF00017.24 CDS31556.2 - 6.8e-11 42.1 0.0 2.3e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 SH2 domain CNOT1_TTP_bind PF16417.5 CDS31556.2 - 0.0077 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain SH2_2 PF14633.6 CDS31556.2 - 0.033 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 SH2 domain DUF799 PF05643.11 CDS31556.2 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) ABC2_membrane PF01061.24 CDS31557.1 - 2.8e-36 124.9 26.5 5.1e-36 124.1 26.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDS31557.1 - 1.6e-21 77.3 0.0 2.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDS31557.1 - 1.1e-06 28.8 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDS31557.1 - 1.9e-05 24.2 0.0 4.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CDS31557.1 - 0.00028 20.1 24.1 0.00028 20.1 24.1 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 CDS31557.1 - 0.003 18.1 0.1 0.003 18.1 0.1 2.0 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CDS31557.1 - 0.0034 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CDS31557.1 - 0.023 14.4 0.1 0.067 12.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDS31557.1 - 0.2 12.1 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PDR_CDR PF06422.12 CDS31557.1 - 5.3 7.0 5.1 0.87 9.5 0.1 2.3 2 0 0 2 2 2 0 CDR ABC transporter HGTP_anticodon PF03129.20 CDS31558.1 - 3e-21 75.4 0.0 1.6e-20 73.1 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDS31558.1 - 6.9e-11 42.4 0.0 2e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 CDS31558.1 - 5.8e-10 39.2 5.7 5.8e-10 39.2 5.7 2.1 2 0 0 2 2 2 1 WHEP-TRS domain DEAD PF00270.29 CDS31559.1 - 3.8e-47 160.3 0.0 2.1e-46 157.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31559.1 - 4e-25 88.3 0.4 1.2e-24 86.8 0.2 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31559.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDS31559.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2283 PF10049.9 CDS31559.1 - 0.32 11.2 1.7 0.79 10.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) BAG PF02179.16 CDS31560.1 - 0.00086 19.7 0.1 0.0016 18.9 0.1 1.5 1 0 0 1 1 1 1 BAG domain Ubiquitin_4 PF18036.1 CDS31560.1 - 0.0062 16.6 0.0 0.18 11.8 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 CDS31560.1 - 0.085 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family ubiquitin PF00240.23 CDS31561.1 - 2.2e-09 37.0 0.0 3.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family BAG PF02179.16 CDS31561.1 - 0.0002 21.7 0.2 0.0003 21.2 0.2 1.3 1 0 0 1 1 1 1 BAG domain Ubiquitin_5 PF18037.1 CDS31561.1 - 0.00081 19.7 0.2 0.0024 18.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain RhoGAP PF00620.27 CDS31562.1 - 1.9e-40 138.2 0.0 1.2e-39 135.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CDS31562.1 - 0.00031 21.2 0.0 0.00079 19.9 0.0 1.7 1 0 0 1 1 1 1 PH domain WW PF00397.26 CDS31562.1 - 0.0035 17.4 3.7 0.0061 16.6 1.2 2.4 2 0 0 2 2 2 1 WW domain Erf4 PF10256.9 CDS31563.1 - 3.9e-26 91.4 0.0 4.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Thiolase_N PF00108.23 CDS31564.1 - 9.7e-73 244.7 0.0 1.7e-72 243.9 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDS31564.1 - 6.9e-39 132.3 0.3 1.8e-35 121.3 0.0 2.6 2 0 0 2 2 2 2 Thiolase, C-terminal domain DUF2587 PF10759.9 CDS31564.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-C3Hc3H PF13891.6 CDS31565.1 - 6.4e-05 23.2 0.8 0.099 13.0 0.1 2.4 2 0 0 2 2 2 2 Potential DNA-binding domain V-ATPase_C PF03223.15 CDS31566.1 - 2.8e-109 365.9 6.2 1.6e-107 360.2 6.2 2.0 1 1 0 1 1 1 1 V-ATPase subunit C Folliculin PF11704.8 CDS31566.1 - 0.027 14.4 0.2 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport BBS2_N PF14781.6 CDS31569.2 - 0.053 13.4 0.0 5.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal TRP_2 PF08344.11 CDS31571.1 - 4.8e-27 94.0 1.6 1.3e-26 92.6 1.6 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.31 CDS31571.1 - 3.2e-21 75.7 12.0 8.7e-21 74.3 11.7 1.8 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 CDS31571.1 - 1e-08 35.6 0.3 1.6e-05 25.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS31571.1 - 2e-07 30.8 1.0 0.21 12.2 0.0 4.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CDS31571.1 - 0.00047 20.7 0.4 0.14 12.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS31571.1 - 0.00072 19.9 1.1 3 8.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDS31571.1 - 0.0034 17.6 0.3 5 7.6 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF1664 PF07889.12 CDS31571.1 - 0.053 13.6 3.0 0.14 12.2 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Transpos_assoc PF13963.6 CDS31571.1 - 0.19 12.0 0.6 2.7 8.4 0.2 2.5 2 0 0 2 2 2 0 Transposase-associated domain DUF3262 PF11660.8 CDS31571.1 - 0.4 11.1 2.5 0.75 10.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) VHS PF00790.19 CDS31572.1 - 5.9e-34 116.9 0.1 1.8e-33 115.3 0.0 1.9 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.8 CDS31572.1 - 1.3e-31 109.0 5.7 1.3e-31 109.0 5.7 3.6 4 0 0 4 4 4 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE PF01363.21 CDS31572.1 - 8.1e-17 61.1 7.5 8.1e-17 61.1 7.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.20 CDS31572.1 - 0.03 14.2 3.9 0.087 12.8 3.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF4407 PF14362.6 CDS31572.1 - 0.73 9.1 22.5 0.067 12.5 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FmdE PF02663.14 CDS31572.1 - 3.8 7.5 7.2 1.9 8.5 0.5 2.7 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon zf-RING_5 PF14634.6 CDS31572.1 - 4.3 7.4 9.0 12 6.0 9.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain SPRY PF00622.28 CDS31573.1 - 4e-12 46.3 0.0 7.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF1712 PF08217.11 CDS31574.2 - 4.4e-14 51.9 2.1 7.4e-13 47.9 0.3 2.2 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Mito_carr PF00153.27 CDS31575.1 - 7.4e-33 112.3 1.9 1.8e-12 47.0 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4507 PF14964.6 CDS31576.1 - 2e-07 30.2 7.9 6.7e-06 25.3 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4507) ATP-synt_DE_N PF02823.16 CDS31577.1 - 7.8e-16 57.8 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Y_phosphatase PF00102.27 CDS31578.2 - 3.3e-151 501.4 0.0 4.5e-78 262.1 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 CDS31578.2 - 9.1e-64 211.8 13.5 2.1e-11 44.0 0.0 9.3 8 1 0 8 8 8 7 Fibronectin type III domain Ig_3 PF13927.6 CDS31578.2 - 8.9e-21 74.3 0.1 9.7e-13 48.5 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CDS31578.2 - 6.5e-19 67.8 0.0 3e-10 40.0 0.0 3.7 5 0 0 5 5 3 2 Immunoglobulin I-set domain Pur_ac_phosph_N PF16656.5 CDS31578.2 - 2.5e-18 66.4 3.2 0.013 16.1 0.0 8.0 7 0 0 7 7 7 4 Purple acid Phosphatase, N-terminal domain ig PF00047.25 CDS31578.2 - 1.1e-13 51.1 0.1 2.6e-08 33.9 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CDS31578.2 - 3.6e-13 49.7 0.4 4.6e-06 26.9 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain DSPc PF00782.20 CDS31578.2 - 1.8e-09 37.5 0.0 0.0008 19.2 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS31578.2 - 1.2e-05 25.4 0.0 0.18 11.7 0.0 3.3 3 0 0 3 3 3 2 Tyrosine phosphatase family V-set PF07686.17 CDS31578.2 - 0.00052 20.2 0.2 0.072 13.3 0.2 3.5 2 1 0 2 2 2 1 Immunoglobulin V-set domain fn3_4 PF16794.5 CDS31578.2 - 0.026 14.4 0.4 33 4.5 0.2 4.9 5 1 0 5 5 5 0 Fibronectin-III type domain PTPlike_phytase PF14566.6 CDS31578.2 - 0.026 14.6 0.2 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Inositol hexakisphosphate C2-set_2 PF08205.12 CDS31578.2 - 0.16 12.0 0.1 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Mt_ATP-synt_B PF05405.14 CDS31582.1 - 0.011 15.4 0.6 0.019 14.6 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SNF2_N PF00176.23 CDS31584.1 - 4.9e-67 226.1 1.1 8.8e-67 225.3 1.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS31584.1 - 1.4e-19 70.5 0.0 5e-19 68.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 CDS31584.1 - 4.8e-11 42.8 10.1 4.8e-11 42.8 10.1 3.7 2 1 1 3 3 3 1 HSA MethyltransfD12 PF02086.15 CDS31584.1 - 0.1 12.3 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF5320 PF17253.2 CDS31584.1 - 6.5 7.9 12.8 1 10.5 1.5 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Fcf1 PF04900.12 CDS31586.1 - 3.9e-14 52.9 0.0 1e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Fcf1 DUF4551 PF15087.6 CDS31586.1 - 0.0045 15.9 2.2 0.0057 15.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) TPR_12 PF13424.6 CDS31587.1 - 3.9e-58 193.7 27.3 3.8e-20 71.9 2.3 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 CDS31587.1 - 3.9e-54 179.1 18.4 2.3e-16 59.1 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31587.1 - 3.9e-28 95.4 15.7 2.1e-06 27.3 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDS31587.1 - 3.2e-26 90.0 23.0 8.1e-08 31.8 0.5 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDS31587.1 - 1e-19 69.0 23.9 0.00035 20.5 0.4 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31587.1 - 1.1e-14 53.3 16.0 0.0014 18.6 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS31587.1 - 3.8e-13 49.5 7.9 1.5e-09 37.7 0.3 3.6 2 1 1 4 4 4 2 MalT-like TPR region TPR_19 PF14559.6 CDS31587.1 - 6.3e-11 42.6 13.7 0.0011 19.5 0.6 4.9 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS31587.1 - 7.3e-11 42.5 14.5 0.0011 19.5 0.1 5.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31587.1 - 1.1e-10 41.4 12.5 0.12 13.3 0.1 6.7 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS31587.1 - 4.8e-10 39.1 8.0 0.13 12.7 0.0 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDS31587.1 - 5.2e-06 26.6 0.0 16 6.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS31587.1 - 1e-05 25.7 10.3 0.0061 16.8 0.1 3.5 2 1 2 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CDS31587.1 - 0.0039 17.3 0.4 48 4.5 0.0 5.0 6 0 0 6 6 5 0 PPR repeat SHNi-TPR PF10516.9 CDS31587.1 - 0.0071 15.8 0.8 5.2 6.6 0.0 4.2 4 0 0 4 4 4 1 SHNi-TPR Rif1_N PF12231.8 CDS31587.1 - 0.0099 14.9 0.0 0.063 12.3 0.0 2.0 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal TPR_20 PF14561.6 CDS31587.1 - 0.013 15.8 4.0 6.4 7.2 0.7 4.4 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 CDS31587.1 - 0.022 14.8 1.0 12 6.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_11 PF13414.6 CDS31587.1 - 0.026 14.2 0.3 0.026 14.2 0.3 5.9 7 1 0 7 7 7 0 TPR repeat Alkyl_sulf_dimr PF14863.6 CDS31587.1 - 0.036 14.5 3.9 4.9 7.6 1.1 3.7 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation MIT PF04212.18 CDS31587.1 - 0.062 13.4 15.2 1.2 9.3 3.6 5.2 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain BRE1 PF08647.11 CDS31587.1 - 0.087 12.9 10.2 0.4 10.8 1.0 3.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 CDS31587.1 - 0.12 11.7 11.5 0.37 10.1 11.5 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CdvA PF18822.1 CDS31587.1 - 0.15 11.9 7.2 1.8 8.4 0.8 3.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Wzy_C_2 PF11846.8 CDS31587.1 - 0.44 10.4 3.3 7.9 6.4 0.0 3.7 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal KASH_CCD PF14662.6 CDS31587.1 - 0.56 10.0 11.1 0.27 11.0 5.2 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Csm1_N PF18504.1 CDS31587.1 - 1.1 9.7 5.6 2 8.8 1.8 3.0 2 1 0 2 2 2 0 Csm1 N-terminal domain TPR_3 PF07720.12 CDS31587.1 - 1.4 9.0 13.8 1.3 9.1 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 CDS31587.1 - 1.8 8.9 11.3 0.65 10.3 1.5 3.6 3 1 0 3 3 3 0 ABC transporter C-terminal domain TPR_6 PF13174.6 CDS31587.1 - 2.1 9.2 14.4 26 5.7 1.3 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat JIP_LZII PF16471.5 CDS31587.1 - 3.5 7.9 6.9 1.3 9.3 1.7 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 CDS31587.1 - 6.2 7.1 9.6 1.5 9.1 2.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.25 CDS31588.1 - 1.2e-43 149.3 0.0 3.9e-43 147.7 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31588.1 - 4.3e-20 72.1 0.0 1.1e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase CNH PF00780.22 CDS31588.1 - 6.7e-19 68.5 0.0 3.1e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 CNH domain Kinase-like PF14531.6 CDS31588.1 - 6.9e-11 42.0 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.22 CDS31588.1 - 3.3e-07 30.1 6.6 8.9e-07 28.7 6.6 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_MLP1_2 PF07926.12 CDS31588.1 - 0.0012 18.9 17.7 0.0012 18.9 17.7 8.7 7 1 0 8 8 7 3 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CDS31588.1 - 0.0078 16.4 1.8 0.0078 16.4 1.8 8.8 5 3 3 9 9 8 1 TATA element modulatory factor 1 TATA binding APH PF01636.23 CDS31588.1 - 0.035 14.0 0.4 0.29 11.0 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 CDS31588.1 - 0.15 12.8 0.0 0.52 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain C1_2 PF03107.16 CDS31588.1 - 0.19 12.1 3.5 0.68 10.3 3.5 2.0 1 0 0 1 1 1 0 C1 domain PBD PF00786.28 CDS31588.1 - 0.32 11.4 2.6 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 P21-Rho-binding domain Pox_A_type_inc PF04508.12 CDS31588.1 - 0.47 10.4 8.6 2.5 8.1 0.0 4.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Anophelin PF10731.9 CDS31590.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Ig_3 PF13927.6 CDS31591.1 - 3.9e-58 194.0 0.0 2.1e-09 37.8 0.0 8.0 7 1 0 7 7 7 7 Immunoglobulin domain I-set PF07679.16 CDS31591.1 - 5.3e-54 180.3 0.0 2.5e-11 43.5 0.0 8.1 7 1 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS31591.1 - 1.3e-36 124.7 0.1 2.8e-06 27.6 0.0 8.1 8 1 0 8 8 8 6 Immunoglobulin domain ig PF00047.25 CDS31591.1 - 1.4e-33 114.9 0.0 1.4e-05 25.1 0.0 8.8 8 1 0 8 8 8 5 Immunoglobulin domain V-set PF07686.17 CDS31591.1 - 3.5e-21 75.4 3.7 0.14 12.3 0.0 11.5 7 5 2 9 9 9 4 Immunoglobulin V-set domain Ig_5 PF16681.5 CDS31591.1 - 1.7e-06 28.3 0.0 6.2 7.3 0.0 6.1 6 1 0 6 6 6 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 CDS31591.1 - 2e-06 27.8 0.4 0.69 10.0 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Izumo-Ig PF16706.5 CDS31591.1 - 0.00014 21.8 0.2 3.8 7.6 0.0 5.4 8 0 0 8 8 8 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CDS31591.1 - 0.00049 20.3 0.0 13 6.1 0.0 5.1 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 CDS31591.1 - 0.00066 19.2 0.0 0.058 13.0 0.0 4.2 6 0 0 6 6 6 1 Immunoglobulin domain HIF-1a_CTAD PF08778.10 CDS31591.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain MCM PF00493.23 CDS31592.2 - 1.5e-99 331.6 0.0 2.3e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS31592.2 - 6e-37 126.3 0.4 1.2e-36 125.3 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS31592.2 - 1.5e-29 102.2 0.3 7.5e-28 96.8 1.1 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CDS31592.2 - 2.5e-16 60.2 0.9 6.7e-16 58.8 0.9 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 CDS31592.2 - 6.8e-13 49.2 13.3 6.8e-13 49.2 13.3 2.3 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 CDS31592.2 - 5.7e-09 35.7 0.0 1.5e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS31592.2 - 2.6e-07 30.7 0.0 7.2e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDS31592.2 - 1.6e-06 28.0 0.0 0.00025 20.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CDS31592.2 - 0.00051 19.8 0.5 0.0026 17.6 0.1 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CDS31592.2 - 0.011 16.1 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UCH PF00443.29 CDS31592.2 - 0.013 15.0 1.2 0.017 14.6 0.3 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Sigma54_activat PF00158.26 CDS31592.2 - 0.089 12.5 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain V_cholerae_RfbT PF05575.11 CDS31593.1 - 0.045 13.0 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein HSP20 PF00011.21 CDS31593.1 - 0.062 13.5 0.0 5.3 7.3 0.0 2.5 2 1 0 2 2 2 0 Hsp20/alpha crystallin family HSP20 PF00011.21 CDS31595.1 - 1e-21 77.0 0.9 7e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDS31595.1 - 8.1e-09 34.9 0.0 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA DUF4330 PF14221.6 CDS31595.1 - 0.04 14.1 0.1 0.069 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Hexapep PF00132.24 CDS31596.1 - 1.4e-11 43.6 17.8 0.00027 20.5 0.9 4.9 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDS31596.1 - 2.2e-06 27.3 10.0 0.0014 18.4 3.2 3.0 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CDS31596.1 - 0.003 16.5 1.3 0.086 11.8 0.0 2.1 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 CDS31596.1 - 0.096 10.8 0.8 0.13 10.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) DER1 PF04511.15 CDS31597.1 - 6e-39 134.0 6.5 6.8e-39 133.8 6.5 1.0 1 0 0 1 1 1 1 Der1-like family Ank_2 PF12796.7 CDS31598.1 - 1.1e-33 115.6 4.5 5e-18 65.5 0.3 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS31598.1 - 1.3e-19 70.2 2.7 1.9e-10 41.1 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS31598.1 - 3.7e-18 65.1 0.5 5.5e-05 23.4 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CDS31598.1 - 5e-16 58.6 4.2 1.1e-05 25.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS31598.1 - 1e-15 56.2 0.3 0.0004 20.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat B2-adapt-app_C PF09066.10 CDS31598.1 - 0.025 14.7 0.2 0.046 13.8 0.2 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain B56 PF01603.20 CDS31599.1 - 2.7e-137 458.2 6.4 3.1e-137 457.9 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) D5_N PF08706.11 CDS31599.1 - 0.033 14.5 0.8 0.076 13.3 0.8 1.6 1 0 0 1 1 1 0 D5 N terminal like DUF4996 PF16387.5 CDS31599.1 - 0.14 12.7 0.3 0.38 11.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function Slu7 PF11708.8 CDS31599.1 - 0.16 11.7 1.5 0.24 11.1 1.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Fumerase PF05681.14 CDS31600.1 - 2.3e-88 296.2 0.0 2.9e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CDS31600.1 - 3.9e-88 294.1 0.0 6.2e-88 293.5 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus DnaJ_C PF01556.18 CDS31601.1 - 3.1e-34 118.2 0.0 4.4e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDS31601.1 - 1.2e-24 86.2 0.3 2.2e-24 85.4 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain AAA_6 PF12774.7 CDS31602.1 - 7.7e-157 521.4 0.0 1.3e-155 517.4 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS31602.1 - 3.7e-138 460.9 11.3 3.7e-138 460.9 11.3 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CDS31602.1 - 1.7e-117 392.1 0.1 8.9e-117 389.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDS31602.1 - 8.6e-104 346.5 0.5 3.7e-102 341.1 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS31602.1 - 5.3e-94 313.4 4.4 4.5e-92 307.1 2.9 3.7 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS31602.1 - 1.2e-79 266.1 0.0 8.1e-78 260.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS31602.1 - 4.9e-61 205.3 0.2 1.5e-60 203.8 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS31602.1 - 1e-49 169.4 6.9 2.6e-49 168.1 6.9 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS31602.1 - 7.1e-47 158.4 0.0 8.4e-46 154.9 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CDS31602.1 - 3.2e-29 101.6 0.0 2.8e-28 98.6 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDS31602.1 - 4.6e-18 65.6 0.0 5.2e-05 23.3 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS31602.1 - 8e-17 61.3 0.0 3.6e-16 59.2 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDS31602.1 - 3.4e-06 27.5 0.0 0.46 10.9 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS31602.1 - 5.1e-06 27.0 1.6 0.38 11.1 0.0 5.5 4 1 1 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 CDS31602.1 - 0.0039 17.5 0.2 5.4 7.3 0.0 4.7 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 CDS31602.1 - 0.01 14.9 0.0 0.041 12.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CDS31602.1 - 0.01 16.2 0.0 8.2 6.9 0.0 3.2 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CDS31602.1 - 0.024 14.4 0.1 3.6 7.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain DUF2294 PF10057.9 CDS31602.1 - 0.025 14.7 0.6 0.095 12.8 0.1 2.4 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2294) AAA_18 PF13238.6 CDS31602.1 - 0.036 14.6 1.5 0.23 12.0 0.0 3.4 3 0 0 3 3 1 0 AAA domain AAA_24 PF13479.6 CDS31602.1 - 0.36 10.5 1.6 19 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 CDS31602.1 - 1.4 8.9 3.8 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit zf-CCCH PF00642.24 CDS31604.1 - 2.7e-09 36.7 2.1 2.7e-09 36.7 2.1 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CSL PF05207.13 CDS31604.1 - 1.1e-06 28.2 0.2 1.1e-06 28.2 0.2 2.6 2 0 0 2 2 2 1 CSL zinc finger zf-C3HC4_3 PF13920.6 CDS31604.1 - 1.3e-06 28.2 7.4 1.3e-06 28.2 7.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CDS31604.1 - 2e-06 27.7 3.5 6.1e-06 26.1 3.5 1.9 1 0 0 1 1 1 1 Zinc finger domain DnaJ PF00226.31 CDS31604.1 - 3.1e-06 27.2 0.0 9.4e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_2 PF13923.6 CDS31604.1 - 6.1e-06 26.0 8.9 6.1e-06 26.0 8.9 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS31604.1 - 1.2e-05 25.1 9.4 4.4e-05 23.3 9.4 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS31604.1 - 3.9e-05 23.5 10.0 3.9e-05 23.5 10.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 CDS31604.1 - 5.9e-05 22.8 1.9 5.9e-05 22.8 1.9 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_UBOX PF13445.6 CDS31604.1 - 0.00018 21.5 5.2 0.00065 19.7 5.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDS31604.1 - 0.0041 17.4 7.6 0.0041 17.4 7.6 2.7 3 0 0 3 3 1 1 Ring finger domain zf-RING_10 PF16685.5 CDS31604.1 - 0.005 16.9 4.9 0.005 16.9 4.9 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDS31604.1 - 0.012 15.4 5.4 0.034 14.0 5.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDS31604.1 - 0.23 11.6 11.7 0.048 13.8 7.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDS31604.1 - 2 8.4 6.8 1.6 8.7 1.8 2.6 1 1 1 2 2 2 0 zf-RING of BARD1-type protein RPAP2_Rtr1 PF04181.13 CDS31605.1 - 3.8e-19 68.8 6.5 6.6e-19 68.0 2.1 2.5 2 0 0 2 2 2 1 Rtr1/RPAP2 family Phytochelatin PF05023.14 CDS31606.1 - 9.2e-71 237.4 0.0 1.5e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Ras PF00071.22 CDS31607.1 - 1.7e-62 209.8 0.2 1.9e-62 209.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS31607.1 - 3.7e-35 120.7 0.1 5.6e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS31607.1 - 4.8e-14 52.2 0.0 6.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS31607.1 - 5.3e-06 26.0 0.0 1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDS31607.1 - 9.6e-05 22.0 0.1 0.0002 20.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS31607.1 - 0.00056 19.8 0.1 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDS31607.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDS31607.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDS31607.1 - 0.0047 17.3 0.0 0.011 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDS31607.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 CDS31608.1 - 1.8e-39 135.5 0.2 1.8e-39 135.5 0.2 2.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CDS31608.1 - 3.5e-06 27.1 0.1 7.9e-05 22.7 0.1 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1593 PF07632.11 CDS31608.1 - 0.00078 19.0 1.3 0.006 16.0 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1593) AbiJ_NTD4 PF18863.1 CDS31608.1 - 0.0024 18.3 10.6 1.8 9.0 6.5 4.0 2 1 0 2 2 2 1 AbiJ N-terminal domain 4 Roc PF08477.13 CDS31608.1 - 0.0035 17.5 0.0 0.77 10.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CDS31608.1 - 0.004 16.7 0.0 0.43 10.1 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CDS31608.1 - 0.004 16.6 0.0 0.73 9.3 0.0 2.7 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 CDS31608.1 - 0.016 15.6 0.2 0.23 11.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Ras PF00071.22 CDS31608.1 - 0.084 12.5 0.5 12 5.4 0.0 3.1 3 0 0 3 3 3 0 Ras family AAA_15 PF13175.6 CDS31608.1 - 0.83 9.3 0.0 0.83 9.3 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain TPR_2 PF07719.17 CDS31609.1 - 3e-08 33.2 6.5 0.05 13.7 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31609.1 - 3.3e-08 33.7 9.5 0.0041 17.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS31609.1 - 3.9e-07 29.6 2.3 0.021 14.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANTH PF07651.16 CDS31609.1 - 0.0025 16.8 3.8 0.0043 16.1 3.8 1.4 1 0 0 1 1 1 1 ANTH domain ANAPC3 PF12895.7 CDS31609.1 - 0.0032 17.6 9.8 0.31 11.3 1.2 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDS31609.1 - 0.017 15.1 0.2 1.2 9.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31609.1 - 0.025 14.8 3.0 3.5 8.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31609.1 - 0.061 14.2 0.0 3 8.9 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS31609.1 - 0.064 13.9 1.0 29 5.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDS31609.1 - 0.15 12.7 0.4 9.9 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS31609.1 - 0.17 11.8 1.7 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GldM_N PF12081.8 CDS31609.1 - 0.56 10.3 5.2 0.11 12.6 0.8 2.0 2 0 0 2 2 2 0 GldM N-terminal domain Arf PF00025.21 CDS31611.1 - 1.6e-73 245.9 0.0 1.7e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDS31611.1 - 2.6e-14 53.1 0.0 3.1e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDS31611.1 - 3.6e-14 53.0 0.0 5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS31611.1 - 2.5e-11 43.5 0.0 2.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDS31611.1 - 8.3e-11 41.6 0.7 4.2e-08 32.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CDS31611.1 - 1.9e-09 37.2 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS31611.1 - 1.4e-05 25.1 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDS31611.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NAP PF00956.18 CDS31612.1 - 0.054 12.7 0.2 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Tnp_P_element_C PF12596.8 CDS31612.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 87kDa Transposase LINES_N PF14694.6 CDS31613.1 - 2.6e-06 27.1 0.7 2.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Lines N-terminus Gp_dh_C PF02800.20 CDS31614.1 - 5.3e-70 234.1 0.0 9.6e-70 233.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDS31614.1 - 3.6e-36 123.6 0.1 7.5e-36 122.5 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GKAP PF03359.13 CDS31615.2 - 5.3e-25 88.7 5.2 5.3e-25 88.7 5.2 3.4 2 1 1 3 3 3 2 Guanylate-kinase-associated protein (GKAP) protein LKAAEAR PF15478.6 CDS31615.2 - 0.0052 17.0 0.3 0.026 14.8 0.5 2.0 2 0 0 2 2 2 1 Family of unknown function with LKAAEAR motif Vip3A_N PF12495.8 CDS31616.1 - 0.0029 17.5 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Vegetative insecticide protein 3A N terminal SNARE PF05739.19 CDS31616.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 SNARE domain PAC2 PF09754.9 CDS31617.1 - 1.2e-24 87.6 0.0 1.6e-24 87.1 0.0 1.3 1 1 0 1 1 1 1 PAC2 family Ras PF00071.22 CDS31618.1 - 2.7e-42 144.1 0.0 3.2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS31618.1 - 1.6e-16 60.6 0.0 2.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS31618.1 - 1.6e-07 30.9 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDS31618.1 - 0.001 19.0 0.0 0.34 10.8 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDS31618.1 - 0.019 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase B56 PF01603.20 CDS31619.1 - 1.8e-186 620.1 7.5 2.1e-186 619.9 7.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SBF2 PF12335.8 CDS31619.1 - 0.047 13.3 0.4 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 Myotubularin protein RIH_assoc PF08454.11 CDS31619.1 - 0.41 10.5 2.5 4.8 7.1 0.0 3.1 3 1 0 3 3 3 0 RyR and IP3R Homology associated Foie-gras_1 PF11817.8 CDS31620.1 - 1.6e-38 132.8 0.7 3.5e-38 131.7 0.1 1.9 2 0 0 2 2 2 1 Foie gras liver health family 1 TPR_1 PF00515.28 CDS31620.1 - 0.029 14.2 0.9 0.1 12.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS31620.1 - 0.046 14.0 3.8 0.097 12.9 0.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDS31620.1 - 0.7 10.2 3.9 0.62 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Gryzun PF07919.12 CDS31622.1 - 3.1e-11 42.8 0.0 2.5e-08 33.2 0.1 2.7 3 0 0 3 3 3 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 CDS31622.1 - 1.1e-08 34.9 0.0 2.7e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 CDS31622.1 - 0.00035 20.3 0.1 0.0016 18.1 0.0 2.1 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 HLH PF00010.26 CDS31623.1 - 4.5e-13 48.9 0.6 9.7e-13 47.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ThiF PF00899.21 CDS31624.2 - 2.9e-60 203.6 0.1 8.8e-60 202.1 0.1 1.7 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 CDS31624.2 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 CDS31624.2 - 0.0033 17.0 0.1 0.0074 15.9 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 CDS31624.2 - 0.007 16.4 0.0 0.31 11.1 0.0 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CDS31624.2 - 0.013 15.9 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CDS31624.2 - 0.034 14.4 0.9 0.38 11.0 0.4 2.8 3 2 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 CDS31624.2 - 0.053 13.2 0.2 0.19 11.3 0.2 2.0 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Longin PF13774.6 CDS31625.1 - 1.4e-22 79.5 0.0 2.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CDS31625.1 - 3.6e-15 55.5 0.4 7.6e-15 54.5 0.1 1.7 2 0 0 2 2 2 1 Synaptobrevin YgaB PF14182.6 CDS31625.1 - 0.023 15.1 0.9 0.057 13.8 0.3 1.9 2 0 0 2 2 2 0 YgaB-like protein Sec20 PF03908.13 CDS31625.1 - 0.04 13.8 0.7 0.073 13.0 0.1 1.8 2 0 0 2 2 2 0 Sec20 GP41 PF00517.17 CDS31625.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein EF-hand_1 PF00036.32 CDS31627.1 - 0.0045 16.4 0.1 0.047 13.3 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CDS31627.1 - 0.031 14.2 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CDS31627.1 - 0.037 14.5 0.0 0.077 13.4 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair Calpain_III PF01067.22 CDS31628.2 - 9.4e-33 113.4 0.0 1.7e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III Peptidase_M28 PF04389.17 CDS31630.1 - 6.4e-36 123.9 0.0 9.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 CDS31630.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Nicastrin THOC7 PF05615.13 CDS31631.1 - 1.7e-26 93.1 5.5 1.7e-26 93.1 5.5 1.5 1 1 0 1 1 1 1 Tho complex subunit 7 SNARE PF05739.19 CDS31631.1 - 0.038 14.0 0.9 0.11 12.5 0.9 1.8 1 0 0 1 1 1 0 SNARE domain CNOT11 PF10155.9 CDS31631.1 - 0.1 12.8 2.7 0.81 9.9 0.6 2.3 1 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 HAD_2 PF13419.6 CDS31631.1 - 0.37 10.9 5.7 0.54 10.3 4.9 1.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4315 PF14193.6 CDS31631.1 - 1.6 8.8 15.9 0.64 10.1 5.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Ribosomal_L15e PF00827.17 CDS31632.1 - 3.5e-83 278.0 4.8 4.1e-83 277.8 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Tubulin PF00091.25 CDS31633.1 - 7.9e-46 156.7 0.0 1.3e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS31633.1 - 2.7e-21 76.1 0.0 6.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Rep_fac_C PF08542.11 CDS31634.1 - 3.8e-24 84.9 0.0 7.4e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CDS31634.1 - 6.4e-13 48.8 0.0 8.4e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CDS31634.1 - 6.5e-11 42.8 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CDS31634.1 - 8.8e-07 28.9 0.4 2.7e-06 27.3 0.0 2.0 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CDS31634.1 - 1.6e-06 28.2 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS31634.1 - 4.2e-06 27.1 0.1 0.0022 18.2 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CDS31634.1 - 5.2e-06 26.9 0.1 7.2e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDS31634.1 - 7.8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 CDS31634.1 - 0.00022 21.1 0.0 0.00041 20.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDS31634.1 - 0.00027 20.7 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CDS31634.1 - 0.00096 18.8 0.1 0.007 16.0 0.1 2.2 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 CDS31634.1 - 0.00097 19.5 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CDS31634.1 - 0.0011 18.8 0.4 0.13 12.1 0.0 2.9 1 1 1 3 3 3 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDS31634.1 - 0.0012 18.2 0.0 0.0054 16.1 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CDS31634.1 - 0.0025 18.4 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CDS31634.1 - 0.0027 17.5 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CDS31634.1 - 0.0053 15.8 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CDS31634.1 - 0.0062 17.1 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MipZ PF09140.11 CDS31634.1 - 0.0077 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_24 PF13479.6 CDS31634.1 - 0.0099 15.6 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDS31634.1 - 0.013 15.9 0.0 0.049 14.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 CDS31634.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDS31634.1 - 0.018 14.7 0.1 0.12 12.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 CDS31634.1 - 0.019 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_23 PF13476.6 CDS31634.1 - 0.023 15.2 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 CDS31634.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain PhoH PF02562.16 CDS31634.1 - 0.033 13.7 0.1 17 4.8 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein AAA_28 PF13521.6 CDS31634.1 - 0.036 14.3 0.1 0.081 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDS31634.1 - 0.04 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 NTPase Pox_H7 PF04787.12 CDS31634.1 - 0.054 14.0 0.1 2.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Late protein H7 ResIII PF04851.15 CDS31634.1 - 0.056 13.5 0.0 0.89 9.5 0.0 2.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 CDS31634.1 - 0.087 12.2 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CDS31634.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T4SS-DNA_transf PF02534.14 CDS31634.1 - 0.13 11.0 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ATPase_2 PF01637.18 CDS31634.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea G-patch PF01585.23 CDS31635.1 - 0.038 13.9 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 G-patch domain Proteasome PF00227.26 CDS31636.2 - 2e-33 115.5 0.0 2.4e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit EGF PF00008.27 CDS31637.2 - 1.1e-11 44.8 19.1 4.5e-06 26.9 3.8 2.9 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 CDS31637.2 - 1.4e-08 35.1 16.8 0.0005 20.6 4.5 3.2 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_2 PF07974.13 CDS31637.2 - 3.5e-06 27.3 15.5 0.0093 16.3 5.0 2.9 2 0 0 2 2 2 2 EGF-like domain GAPT PF11770.8 CDS31637.2 - 0.0055 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) Laminin_EGF PF00053.24 CDS31637.2 - 0.34 11.1 15.7 2.8 8.2 3.8 3.2 1 1 0 2 2 2 0 Laminin EGF domain EGF_CA PF07645.15 CDS31637.2 - 4.4 7.6 13.9 6.1 7.1 2.6 3.1 2 1 0 2 2 2 0 Calcium-binding EGF domain Trypan_PARP PF05887.11 CDS31640.1 - 7.8 6.5 37.3 10 6.1 37.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rad10 PF03834.14 CDS31643.1 - 0.1 12.6 1.5 0.31 11.1 0.9 1.8 1 1 1 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) PDGF PF00341.17 CDS31644.2 - 0.003 17.8 4.7 0.053 13.8 0.8 2.9 2 0 0 2 2 2 2 PDGF/VEGF domain DUF678 PF05077.12 CDS31645.1 - 0.09 12.9 2.2 0.14 12.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Aldolase_II PF00596.21 CDS31646.1 - 7.9e-37 127.0 0.3 1.3e-36 126.3 0.3 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain T3SchapCesA PF11439.8 CDS31646.1 - 0.0032 17.6 0.5 0.18 12.0 0.1 2.6 3 0 0 3 3 3 1 Type III secretion system filament chaperone CesA CK_II_beta PF01214.18 CDS31647.1 - 0.0098 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit TPH PF13868.6 CDS31649.2 - 6.7e-74 248.5 135.9 6.7e-74 248.5 135.9 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RQC PF09382.10 CDS31650.1 - 3e-20 72.1 0.0 1.3e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 RQC domain DEAD PF00270.29 CDS31650.1 - 2.3e-19 69.9 0.0 4.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31650.1 - 7.7e-18 64.9 0.0 3.9e-15 56.2 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDS31650.1 - 2.7e-16 60.0 1.4 9.1e-15 55.2 0.6 2.9 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 CDS31650.1 - 1.1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 CDS31650.1 - 5.8e-07 29.7 0.0 3.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HTH_51 PF18558.1 CDS31650.1 - 0.14 12.1 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CLTH PF10607.9 CDS31651.1 - 4.9e-26 91.4 0.1 8.9e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDS31651.1 - 8.4e-10 38.3 0.3 1.9e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 LisH Bax1-I PF01027.20 CDS31652.1 - 1.2e-29 103.7 30.3 1.3e-29 103.5 30.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Macoilin PF09726.9 CDS31652.1 - 8.4 4.8 5.5 12 4.3 5.5 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_L18 PF17135.4 CDS31653.1 - 9.6e-73 243.6 2.5 1e-72 243.4 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e HTH_41 PF14502.6 CDS31653.1 - 0.028 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L27A PF00828.19 CDS31653.1 - 0.054 14.2 0.1 0.12 13.0 0.1 1.7 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ATR13 PF16829.5 CDS31653.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Sdh_cyt PF01127.22 CDS31654.1 - 2.2 8.4 7.0 7.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit GON PF08685.11 CDS31656.1 - 1.5e-53 181.6 0.3 4.5e-53 180.1 0.3 1.9 1 0 0 1 1 1 1 GON domain TSP_1 PF00090.19 CDS31656.1 - 5.6e-24 84.1 89.5 3.1e-09 36.9 9.1 11.7 11 0 0 11 11 11 7 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 CDS31656.1 - 1.2e-13 51.3 7.2 1.2e-13 51.3 7.2 4.7 4 0 0 4 4 4 2 ADAM cysteine-rich domain Reprolysin_4 PF13583.6 CDS31656.1 - 2.1e-06 27.6 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDS31656.1 - 1.1e-05 25.6 4.6 1.9e-05 24.9 1.2 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CDS31656.1 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CDS31656.1 - 0.001 19.6 0.6 0.0033 18.0 0.3 2.0 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 CDS31656.1 - 0.0069 16.4 0.1 0.047 13.7 0.0 2.3 2 0 0 2 2 2 1 ADAM-TS Spacer 1 Reprolysin PF01421.19 CDS31656.1 - 0.049 13.5 7.0 0.26 11.1 0.0 3.6 2 1 2 4 4 4 0 Reprolysin (M12B) family zinc metalloprotease RNase_T PF00929.24 CDS31657.1 - 3.6e-20 73.2 0.0 7.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Trypsin PF00089.26 CDS31658.1 - 1e-28 100.7 0.0 1.3e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Trypsin NIF PF03031.18 CDS31660.1 - 5e-49 166.0 0.2 1.1e-48 164.9 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4685 PF15737.5 CDS31660.1 - 0.24 11.9 1.9 0.75 10.2 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) RVP PF00077.20 CDS31661.1 - 2.4e-06 27.8 0.0 0.0006 20.1 0.0 3.2 3 0 0 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDS31661.1 - 1.1e-05 25.9 0.0 0.0045 17.5 0.0 2.6 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS31661.1 - 0.0014 19.3 0.0 0.15 12.8 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease DUF1907 PF08925.11 CDS31661.1 - 0.1 12.0 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1907) gag-asp_proteas PF13975.6 CDS31663.1 - 0.00076 20.0 0.0 1.3 9.6 0.0 2.8 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS31663.1 - 0.0011 19.6 0.0 1.2 9.8 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CDS31664.1 - 6e-05 23.5 0.0 0.21 12.2 0.0 2.7 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS31664.1 - 0.00021 21.9 0.0 0.24 12.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 CDS31664.1 - 0.0032 17.7 0.0 4.1 7.8 0.0 3.0 2 1 0 2 2 2 2 Retroviral aspartyl protease Peptidase_C48 PF02902.19 CDS31665.1 - 5.8e-10 39.4 7.8 2.5e-09 37.3 7.8 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Thioredoxin_6 PF13848.6 CDS31665.1 - 0.061 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PTPLA PF04387.14 CDS31666.1 - 2.2e-48 164.1 6.6 3.3e-48 163.5 6.6 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CS PF04969.16 CDS31666.1 - 1.8e-06 28.8 0.0 3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 CS domain Renin_r PF07850.14 CDS31666.1 - 0.11 13.0 0.1 26 5.5 0.0 2.6 2 0 0 2 2 2 0 Renin receptor-like protein Sugar_tr PF00083.24 CDS31667.1 - 3.1e-25 89.0 16.6 7e-25 87.8 16.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS31667.1 - 1.2e-20 73.8 22.3 9.3e-18 64.3 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDS31667.1 - 0.0054 16.1 5.8 0.011 15.1 5.8 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 CDS31667.1 - 1.4 7.8 11.9 0.55 9.2 7.1 2.1 2 0 0 2 2 2 0 PUCC protein PDZ_5 PF17817.1 CDS31668.1 - 7.1e-21 74.3 0.5 7.1e-21 74.3 0.5 2.7 2 1 0 2 2 2 1 PDZ domain VIR_N PF15912.5 CDS31668.1 - 0.0031 17.2 9.1 0.0031 17.2 9.1 1.7 3 0 0 3 3 3 1 Virilizer, N-terminal DNA_pol_phi PF04931.13 CDS31668.1 - 5.7 4.9 10.1 8.4 4.4 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi PDZ PF00595.24 CDS31669.1 - 0.067 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain SlyX PF04102.12 CDS31669.1 - 0.48 11.1 2.7 3.6 8.3 1.3 3.0 1 1 1 2 2 2 0 SlyX CS PF04969.16 CDS31673.1 - 0.00051 21.0 0.0 0.00078 20.4 0.0 1.3 1 0 0 1 1 1 1 CS domain NOA36 PF06524.12 CDS31673.1 - 0.25 10.6 7.7 0.31 10.3 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein DSPc PF00782.20 CDS31674.1 - 2.7e-05 24.0 0.3 4.6e-05 23.2 0.3 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF294_C PF10335.9 CDS31674.1 - 0.032 14.0 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain BOP1NT PF08145.12 CDS31675.1 - 1.5e-56 192.3 3.2 3e-55 187.9 3.2 2.5 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CDS31675.1 - 3.1e-08 34.1 12.1 8e-06 26.5 0.6 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat BppL_N PF18338.1 CDS31675.1 - 0.16 11.8 0.2 0.46 10.3 0.2 1.7 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain PQQ_3 PF13570.6 CDS31675.1 - 0.2 12.2 0.4 23 5.7 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.25 CDS31676.1 - 2.6e-47 161.4 0.0 3.3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31676.1 - 9.8e-26 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31676.1 - 2.9e-09 36.7 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS31676.1 - 0.0064 15.9 0.2 0.012 15.0 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS31676.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family TRM PF02005.16 CDS31677.1 - 4.2e-19 69.0 0.0 5.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase 7tm_1 PF00001.21 CDS31678.1 - 2.4e-14 53.3 12.8 3.9e-14 52.6 12.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Gaa1 PF04114.14 CDS31678.1 - 8.1 5.3 12.8 2.2 7.2 2.7 2.1 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component TRM PF02005.16 CDS31679.1 - 1.4e-100 337.1 0.0 1.8e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CDS31679.1 - 5.2e-08 32.9 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 CDS31679.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 CDS31679.1 - 0.052 12.7 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CpXC PF14353.6 CDS31679.1 - 0.084 12.9 0.6 0.3 11.1 0.0 2.2 3 0 0 3 3 3 0 CpXC protein Birna_VP4 PF01768.16 CDS31679.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein zinc_ribbon_5 PF13719.6 CDS31679.1 - 0.53 10.1 0.1 0.53 10.1 0.1 2.6 4 0 0 4 4 4 0 zinc-ribbon domain 14-3-3 PF00244.20 CDS31680.1 - 6e-91 303.9 7.8 6.9e-91 303.7 7.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF5446 PF17522.2 CDS31680.1 - 0.088 13.0 1.4 0.17 12.1 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) RAD51_interact PF15696.5 CDS31680.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RAD51 interacting motif Dynein_light PF01221.18 CDS31682.1 - 1.8e-27 95.5 0.2 2.4e-27 95.1 0.2 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1852 PF08908.11 CDS31682.1 - 0.081 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Dynein_light PF01221.18 CDS31683.1 - 1.8e-41 140.3 0.7 2e-41 140.2 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 CDS31683.1 - 0.18 11.7 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Ectatomin Collagen PF01391.18 CDS31685.2 - 1.2e-162 527.8 655.5 8.5e-08 31.8 37.3 21.6 2 1 8 10 10 10 6 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CDS31685.2 - 1.5e-30 106.2 0.0 2.1e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 CDS31685.2 - 4.7e-06 26.8 14.1 7.4e-06 26.2 14.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type C domain UPF0506 PF11703.8 CDS31687.1 - 0.00078 19.8 3.7 0.0017 18.7 3.7 1.5 1 0 0 1 1 1 1 UPF0506 Tachystatin_A PF11406.8 CDS31687.1 - 0.0016 18.5 3.6 0.0045 17.0 3.6 1.8 1 0 0 1 1 1 1 Antimicrobial peptide tachystatin A Pkinase PF00069.25 CDS31688.2 - 0.0002 20.8 0.0 0.17 11.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 CDS31688.2 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS31688.2 - 0.024 14.6 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DBC1 PF14443.6 CDS31689.1 - 2.8e-39 133.9 0.0 6.5e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 CDS31689.1 - 2.5e-10 39.9 0.1 9e-10 38.1 0.1 2.1 1 0 0 1 1 1 1 SAP domain Nup54 PF13874.6 CDS31689.1 - 0.0084 16.2 4.6 0.025 14.7 4.6 1.8 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Malic_M PF03949.15 CDS31690.2 - 1.8e-88 296.1 0.0 2.4e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDS31690.2 - 4.1e-77 258.1 0.0 6.8e-77 257.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LRR_8 PF13855.6 CDS31692.1 - 1.4e-48 162.4 33.3 2.7e-15 55.9 1.6 5.8 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CDS31692.1 - 2.1e-20 72.5 34.8 4.1e-05 23.8 1.8 7.7 2 2 8 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDS31692.1 - 7.2e-17 61.6 0.0 0.00019 21.4 0.0 4.3 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CDS31692.1 - 8.2e-12 45.0 6.0 3.7e-05 23.3 1.5 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CDS31692.1 - 1.1e-11 43.6 21.3 1.8 9.4 0.2 10.2 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.6 CDS31692.1 - 0.003 17.5 27.9 4.1 7.7 0.1 8.8 9 0 0 9 9 9 3 Leucine Rich repeat TMEM154 PF15102.6 CDS31692.1 - 0.055 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family ANF_receptor PF01094.28 CDS31694.1 - 7.4e-29 101.0 0.9 3.5e-22 79.0 0.2 2.1 1 1 1 2 2 2 2 Receptor family ligand binding region Vps4_C PF09336.10 CDS31694.1 - 0.093 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PRKG1_interact PF15898.5 CDS31695.1 - 3e-12 47.3 12.5 1.3e-11 45.3 11.3 2.4 2 1 0 2 2 2 1 cGMP-dependent protein kinase interacting domain DUF2205 PF10224.9 CDS31695.1 - 0.057 13.4 3.2 2.5 8.1 1.8 2.3 1 1 0 2 2 2 0 Short coiled-coil protein Endotoxin_N PF03945.14 CDS31695.1 - 0.14 11.8 0.4 0.2 11.3 0.4 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF4407 PF14362.6 CDS31695.1 - 0.15 11.4 2.8 0.24 10.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 CDS31695.1 - 0.23 11.6 8.1 0.42 10.7 8.0 1.5 1 1 0 1 1 1 0 TolA binding protein trimerisation CHASE6_C PF17150.4 CDS31695.1 - 0.25 12.1 2.9 0.4 11.4 1.5 1.9 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain DUF3496 PF12001.8 CDS31695.1 - 2.9 8.3 6.9 4.9 7.6 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Cullin PF00888.22 CDS31696.1 - 1e-146 490.1 2.2 1.4e-146 489.7 2.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS31696.1 - 4.3e-19 68.3 1.7 1.1e-18 67.0 1.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF573 PF04504.14 CDS31697.1 - 0.28 11.9 8.3 1.6 9.4 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF812 PF05667.11 CDS31697.1 - 0.96 8.3 23.7 1.8 7.4 23.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CI-B14_5a PF07347.12 CDS31699.1 - 1.2e-32 111.6 0.1 1.4e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DEAD PF00270.29 CDS31700.2 - 1.4e-15 57.5 0.1 2.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31700.2 - 2.1e-12 47.4 0.0 4.5e-11 43.1 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31700.2 - 1.5e-09 38.1 0.0 5.8e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 CDS31700.2 - 1.7e-05 25.4 0.0 6.6e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 CDS31700.2 - 0.038 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Cdd1 PF11731.8 CDS31700.2 - 0.086 13.1 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Pathogenicity locus DUF1694 PF07997.11 CDS31700.2 - 0.1 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) ERbeta_N PF12497.8 CDS31700.2 - 0.1 12.4 1.4 0.23 11.3 1.4 1.5 1 0 0 1 1 1 0 Estrogen receptor beta Thioredoxin PF00085.20 CDS31701.1 - 2.7e-08 33.7 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CDS31701.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CDS31701.1 - 0.052 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin RRM_1 PF00076.22 CDS31702.1 - 1.4e-16 60.1 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDS31702.1 - 0.022 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CodY PF06018.14 CDS31702.1 - 0.055 13.0 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 CodY GAF-like domain MFS_1 PF07690.16 CDS31703.1 - 3.4e-34 118.3 34.7 3.6e-26 91.9 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Terminase_4 PF05119.12 CDS31704.1 - 0.067 13.6 0.4 3 8.3 0.1 2.3 2 0 0 2 2 2 0 Phage terminase, small subunit MDD_C PF18376.1 CDS31706.2 - 6.9e-54 182.4 0.1 1.4e-53 181.5 0.1 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CDS31706.2 - 6.7e-06 26.2 4.0 1.6e-05 25.0 2.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain Brix PF04427.18 CDS31707.1 - 1e-24 87.7 0.0 1.5e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain PH PF00169.29 CDS31708.1 - 1.2e-13 51.4 1.4 5.3e-13 49.4 0.2 2.6 3 0 0 3 3 3 1 PH domain SAM_1 PF00536.30 CDS31708.1 - 2.2e-09 37.6 0.0 5.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS31708.1 - 5.6e-09 36.0 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CRIC_ras_sig PF10534.9 CDS31708.1 - 3.2e-06 27.2 0.6 1.1e-05 25.5 0.6 2.0 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras PDZ_6 PF17820.1 CDS31708.1 - 3e-05 23.8 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDS31708.1 - 0.0013 19.0 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.6 CDS31708.1 - 2.7 8.5 7.6 2.6 8.5 4.3 2.8 3 1 0 3 3 3 0 Pleckstrin homology domain Biotin_carb_N PF00289.22 CDS31709.1 - 6.8e-27 94.2 0.3 1.1e-26 93.5 0.3 1.3 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain MFS_2 PF13347.6 CDS31710.2 - 1.5e-87 294.0 25.5 1.7e-87 293.8 25.5 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1772 PF08592.11 CDS31710.2 - 0.4 11.0 14.3 0.95 9.8 0.4 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Ank_4 PF13637.6 CDS31712.1 - 1.6e-25 89.1 0.3 5.4e-11 42.8 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS31712.1 - 1.8e-16 60.5 0.0 1.8e-12 47.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDS31712.1 - 1.9e-14 53.3 0.0 9.4e-05 22.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CDS31712.1 - 6.3e-14 50.7 0.0 0.00056 20.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CDS31712.1 - 3.1e-09 36.9 0.0 0.0011 19.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) EGF_2 PF07974.13 CDS31714.1 - 1.4e-21 76.5 127.6 0.00043 20.6 13.9 8.7 8 0 0 8 8 8 8 EGF-like domain Cadherin PF00028.17 CDS31715.2 - 5.3e-64 212.7 1.2 1.2e-13 51.3 0.0 8.7 9 0 0 9 9 9 8 Cadherin domain Cadherin_2 PF08266.12 CDS31715.2 - 1.7e-07 31.0 2.4 0.00024 20.9 0.5 3.9 5 0 0 5 5 5 2 Cadherin-like Ras PF00071.22 CDS31717.2 - 2.5e-07 30.4 0.0 0.00014 21.5 0.0 2.7 3 0 0 3 3 3 2 Ras family RhoGAP-FF1 PF16512.5 CDS31717.2 - 1.4e-05 25.6 2.1 2.6e-05 24.8 0.8 2.2 2 0 0 2 2 2 1 p190-A and -B Rho GAPs FF domain Roc PF08477.13 CDS31717.2 - 0.057 13.6 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF4026 PF13218.6 CDS31717.2 - 0.085 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) AAA_22 PF13401.6 CDS31717.2 - 0.16 12.3 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 CDS31718.1 - 4.3e-101 336.7 0.2 6.9e-101 336.0 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS31718.1 - 4.5e-34 117.0 0.7 9.5e-34 116.0 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 CDS31718.1 - 2.6e-29 101.6 0.4 5.7e-29 100.5 0.4 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CDS31718.1 - 9.9e-26 90.0 0.5 2.6e-25 88.6 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDS31718.1 - 1.1e-17 64.5 0.6 2.5e-17 63.4 0.6 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDS31718.1 - 4.9e-07 29.3 0.0 2.3e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDS31718.1 - 0.00025 20.9 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDS31718.1 - 0.0012 18.5 0.1 0.007 16.1 0.1 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDS31718.1 - 0.0013 18.7 0.0 0.005 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PDEase_I PF00233.19 CDS31720.1 - 8.8e-69 231.8 0.7 1.3e-68 231.3 0.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_A22B PF04258.13 CDS31721.1 - 5.8e-36 124.5 25.6 1.8e-35 122.8 25.6 1.8 1 1 0 1 1 1 1 Signal peptide peptidase Abhydrolase_6 PF12697.7 CDS31721.1 - 5e-18 66.5 0.0 8.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDS31721.1 - 2.1e-15 56.7 0.0 6.9e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDS31721.1 - 1.9e-13 50.7 0.0 4.4e-12 46.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold SPP PF06550.11 CDS31721.1 - 2.4e-06 27.2 0.1 2.4e-06 27.2 0.1 2.5 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease HTH_53 PF18606.1 CDS31721.1 - 0.069 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Peptidase_S15 PF02129.18 CDS31721.1 - 0.11 12.1 0.1 49 3.4 0.1 3.1 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Oxidored_q3 PF00499.20 CDS31721.1 - 9.6 5.9 22.6 6.7 6.4 19.4 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MRP-S26 PF14943.6 CDS31722.1 - 2.2e-41 141.6 8.3 2.6e-41 141.4 8.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 MRP-63 PF14978.6 CDS31722.1 - 0.18 12.4 2.9 0.2 12.3 0.5 2.1 1 1 1 2 2 2 0 Mitochondrial ribosome protein 63 FERM_M PF00373.18 CDS31724.1 - 2e-08 34.6 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDS31724.1 - 3.2e-05 23.8 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FERM N-terminal domain zf-HC5HC2H_2 PF13832.6 CDS31725.1 - 3.4e-35 120.5 6.5 3.4e-35 120.5 6.5 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDS31725.1 - 4.6e-25 87.7 4.6 4.6e-25 87.7 4.6 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 CDS31725.1 - 3.1e-19 68.8 0.1 9.2e-19 67.3 0.1 1.8 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.9 CDS31725.1 - 4.5e-18 66.1 0.1 4.5e-18 66.1 0.1 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like PWWP PF00855.17 CDS31725.1 - 2.3e-14 53.6 0.0 1.1e-13 51.3 0.0 2.3 1 1 0 1 1 1 1 PWWP domain PHD_2 PF13831.6 CDS31725.1 - 7.1e-14 51.1 3.3 7.1e-14 51.1 3.3 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CDS31725.1 - 1.6e-08 34.3 28.0 4.3e-08 32.9 7.7 3.4 3 0 0 3 3 3 2 PHD-finger zf-C3HC PF07967.13 CDS31725.1 - 0.014 15.4 0.8 0.072 13.1 0.8 2.2 1 0 0 1 1 1 0 C3HC zinc finger-like PVL_ORF50 PF07768.11 CDS31725.1 - 0.41 11.0 3.7 12 6.2 1.2 2.8 2 0 0 2 2 2 0 PVL ORF-50-like family C1_2 PF03107.16 CDS31725.1 - 0.47 10.8 15.6 1 9.7 4.3 2.8 2 0 0 2 2 2 0 C1 domain Ribosomal_S8 PF00410.19 CDS31726.1 - 1.4e-23 83.3 0.0 2e-23 82.7 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein S8 DUF1491 PF07372.12 CDS31726.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Nucleo_LEF-12 PF06256.11 CDS31726.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Tubulin PF00091.25 CDS31727.1 - 3.3e-69 233.1 0.0 5.1e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS31727.1 - 4.9e-43 146.3 0.1 7.9e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS31727.1 - 2.3e-05 24.7 0.0 6.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDS31727.1 - 0.0051 16.5 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDS31727.1 - 0.025 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tropomyosin_1 PF12718.7 CDS31728.1 - 0.026 14.7 14.6 0.59 10.3 7.4 2.4 2 0 0 2 2 2 0 Tropomyosin like DUF1699 PF08004.11 CDS31728.1 - 0.099 12.3 1.7 0.16 11.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) DUF1664 PF07889.12 CDS31728.1 - 0.2 11.7 3.4 0.68 10.0 3.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sbi-IV PF11621.8 CDS31728.1 - 0.36 11.2 2.0 0.98 9.8 2.0 1.7 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI Prefoldin PF02996.17 CDS31728.1 - 0.36 10.7 9.9 0.26 11.2 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit UPF0242 PF06785.11 CDS31728.1 - 0.6 10.2 17.5 8.3 6.5 0.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 CDS31728.1 - 1.5 9.0 11.2 0.33 11.1 6.9 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Rootletin PF15035.6 CDS31728.1 - 2.7 8.0 18.8 5.9 6.9 18.8 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 CDS31728.1 - 8.9 7.0 11.6 2.1 9.0 7.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF2615 PF11027.8 CDS31729.1 - 1.4e-16 60.6 0.1 1.5e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Crust_neuro_H PF03858.13 CDS31729.1 - 0.19 12.6 0.6 45 5.0 0.3 2.9 2 1 0 2 2 2 0 Crustacean neurohormone H RIBIOP_C PF04950.12 CDS31730.1 - 6.7e-76 255.5 0.4 6.7e-76 255.5 0.4 2.2 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDS31730.1 - 3.1e-24 84.9 0.1 1.3e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CDS31730.1 - 5.9e-05 22.7 0.0 0.014 14.9 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS31730.1 - 0.00056 20.0 0.2 0.022 14.8 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDS31730.1 - 0.0058 17.0 3.2 0.0097 16.3 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 CDS31730.1 - 0.0085 16.6 0.1 0.17 12.4 0.0 3.2 3 1 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 CDS31730.1 - 0.035 14.6 0.0 0.035 14.6 0.0 3.5 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 CDS31730.1 - 0.06 13.9 0.0 0.24 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDS31730.1 - 0.092 12.8 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 CDS31730.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Dynamin_N PF00350.23 CDS31730.1 - 0.3 11.1 1.8 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ADIP PF11559.8 CDS31731.1 - 0.014 15.4 19.8 0.014 15.4 19.8 10.4 4 2 7 11 11 11 0 Afadin- and alpha -actinin-Binding Ribosomal_L14 PF00238.19 CDS31732.1 - 1.7e-36 125.0 0.1 2.1e-36 124.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e 7tm_1 PF00001.21 CDS31733.1 - 1.9e-15 56.9 13.8 5e-15 55.5 13.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rep_fac-A_C PF08646.10 CDS31734.2 - 0.11 12.2 0.3 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Replication factor-A C terminal domain YtzH PF14165.6 CDS31735.1 - 0.08 13.3 0.6 0.12 12.8 0.6 1.3 1 0 0 1 1 1 0 YtzH-like protein REPA_OB_2 PF16900.5 CDS31735.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Replication protein A OB domain Peptidase_C34 PF05413.11 CDS31736.1 - 0.018 15.3 1.0 0.05 13.9 0.1 2.2 3 0 0 3 3 3 0 Putative closterovirus papain-like endopeptidase YojJ PF10372.9 CDS31736.1 - 0.067 13.3 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus LicD PF04991.13 CDS31737.1 - 7e-14 52.5 1.1 8.1e-11 42.5 0.1 2.5 1 1 2 3 3 3 2 LicD family BRO1 PF03097.18 CDS31738.1 - 2e-91 306.7 1.5 2.7e-91 306.3 0.0 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDS31738.1 - 4.3e-63 213.3 9.4 4.3e-63 213.3 9.4 2.4 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV UvrD-helicase PF00580.21 CDS31738.1 - 0.0097 15.5 3.3 0.019 14.5 3.3 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Takusan PF04822.13 CDS31738.1 - 0.029 14.3 3.0 0.043 13.7 1.3 2.2 2 0 0 2 2 2 0 Takusan YscO PF07321.12 CDS31738.1 - 0.23 11.4 5.4 0.24 11.4 0.2 3.3 3 1 0 3 3 3 0 Type III secretion protein YscO Sec34 PF04136.15 CDS31738.1 - 2.2 8.1 10.3 1.4 8.8 1.0 3.2 2 1 1 3 3 3 0 Sec34-like family Glyco_transf_22 PF03901.17 CDS31739.1 - 3e-33 115.7 22.9 3.7e-33 115.4 22.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SH3_9 PF14604.6 CDS31740.1 - 6e-13 48.4 0.2 9.1e-13 47.9 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS31740.1 - 8.6e-10 38.1 0.7 2.2e-09 36.8 0.7 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS31740.1 - 1.3e-06 28.0 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain HTH_11 PF08279.12 CDS31742.2 - 0.017 15.1 0.1 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 HTH domain EF-hand_7 PF13499.6 CDS31743.1 - 1.9e-14 53.9 0.0 1.3e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CDS31743.1 - 7.5e-11 42.2 0.0 3e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 CDS31743.1 - 3.2e-10 39.1 0.0 0.00082 19.1 0.0 3.9 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CDS31743.1 - 3.8e-10 38.6 0.0 0.015 14.8 0.0 5.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CDS31743.1 - 5.6e-10 38.9 0.7 5.8e-05 22.8 0.0 4.0 1 1 3 4 4 4 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 CDS31743.1 - 0.0001 22.3 0.1 0.00059 19.9 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand CAP-ZIP_m PF15255.6 CDS31744.1 - 0.029 14.6 0.1 0.071 13.4 0.1 1.7 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region RhoGAP PF00620.27 CDS31745.2 - 2.9e-32 111.6 0.1 5.9e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain SAM_KSR1 PF13543.6 CDS31745.2 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF3720 PF12517.8 CDS31745.2 - 3.5 8.6 5.5 19 6.2 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3720) Homeodomain PF00046.29 CDS31746.1 - 1.3e-11 44.2 0.9 3.1e-11 43.0 0.9 1.6 1 0 0 1 1 1 1 Homeodomain YfdX PF10938.8 CDS31746.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 YfdX protein Acetyltransf_6 PF13480.7 CDS31746.1 - 0.07 13.3 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 CDS31748.1 - 0.0012 19.2 0.7 0.0027 18.0 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDS31748.1 - 0.14 12.7 0.2 0.48 11.0 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type HLH PF00010.26 CDS31749.1 - 3.7e-09 36.4 2.4 9.4e-09 35.1 2.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain LMF1 PF06762.14 CDS31750.1 - 7.5e-92 308.7 6.7 7.5e-92 308.7 6.7 1.8 2 0 0 2 2 2 1 Lipase maturation factor LRR_8 PF13855.6 CDS31752.1 - 1.6e-54 181.5 53.0 4.4e-13 48.8 2.9 8.8 4 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 CDS31752.1 - 1.5e-33 114.2 68.1 6.5e-06 26.4 0.9 10.4 6 2 6 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS31752.1 - 2.7e-07 30.2 27.4 0.051 13.1 1.8 6.0 1 1 5 7 7 7 7 Leucine-rich repeat LRR_1 PF00560.33 CDS31752.1 - 1.3e-05 25.1 65.5 0.27 12.0 0.3 16.4 16 3 0 16 16 16 3 Leucine Rich Repeat LRR_5 PF13306.6 CDS31752.1 - 0.0071 16.3 1.0 0.077 13.0 0.3 3.0 4 1 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CDS31752.1 - 0.01 15.8 45.2 0.95 9.7 0.0 11.2 13 0 0 13 13 13 0 Leucine Rich repeat DUF2322 PF10084.9 CDS31752.1 - 0.071 13.2 0.1 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Frizzled PF01534.17 CDS31753.2 - 1.6e-126 421.8 18.4 2e-126 421.4 18.4 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDS31753.2 - 5.4e-13 49.5 1.4 1.2e-12 48.5 1.4 1.6 1 0 0 1 1 1 1 Fz domain SH3_9 PF14604.6 CDS31754.1 - 1e-16 60.5 0.2 2e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Abi_HHR PF07815.14 CDS31754.1 - 3.2e-15 56.0 0.0 9.9e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 CDS31754.1 - 6.7e-15 54.4 0.3 1.2e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDS31754.1 - 7.3e-12 44.8 0.1 1.4e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain HAD_SAK_1 PF10307.9 CDS31754.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Exo_endo_phos_2 PF14529.6 CDS31756.2 - 2.2e-07 30.7 0.6 4.7e-07 29.7 0.2 1.8 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS31756.2 - 0.00025 20.6 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.26 CDS31757.1 - 4.9e-17 61.9 0.1 9.7e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDS31761.2 - 3e-21 75.5 0.0 5.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDS31762.2 - 3.4e-20 72.1 0.0 6.4e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rad51 PF08423.11 CDS31764.1 - 2.9e-10 39.8 0.0 2.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 S1 PF00575.23 CDS31770.1 - 2.3e-15 56.7 0.2 2e-05 24.8 0.3 6.2 5 1 0 5 5 5 4 S1 RNA binding domain PP2C PF00481.21 CDS31771.1 - 2.4e-77 260.0 0.0 3e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDS31771.1 - 6.8e-08 32.4 0.0 2.3e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CDS31771.1 - 3.6e-06 27.3 0.0 9.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain SpoIIE PF07228.12 CDS31771.1 - 0.0015 18.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) V-ATPase_G PF03179.15 CDS31772.1 - 1e-10 42.1 7.9 1.2e-10 41.9 7.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RPN6_N PF18055.1 CDS31772.1 - 0.013 15.9 2.5 0.015 15.7 1.9 1.4 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF1826 PF08856.11 CDS31772.1 - 0.016 15.2 0.8 0.019 14.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) DNA_repr_REX1B PF14966.6 CDS31772.1 - 0.024 15.3 2.8 0.034 14.8 2.8 1.2 1 0 0 1 1 1 0 DNA repair REX1-B Tnp_DNA_bind PF14706.6 CDS31772.1 - 0.025 14.4 0.1 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 Transposase DNA-binding DUF515 PF04415.12 CDS31772.1 - 0.098 11.0 3.1 0.11 10.9 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) VPS11_C PF12451.8 CDS31772.1 - 5.1 7.4 6.1 33 4.8 0.4 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal Pkinase PF00069.25 CDS31773.1 - 1.4e-43 149.1 0.0 1.6e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31773.1 - 1.7e-21 76.7 0.0 2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS31773.1 - 0.0048 16.2 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-CCHC PF00098.23 CDS31777.2 - 2.6e-25 87.3 24.0 7.7e-09 35.2 2.1 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CDS31777.2 - 0.00029 20.7 15.9 0.2 11.7 1.5 3.3 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 CDS31777.2 - 0.00069 19.3 15.4 0.46 10.2 1.0 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 CDS31777.2 - 0.0049 16.7 14.2 0.19 11.6 0.1 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 CDS31777.2 - 0.0049 16.6 0.9 0.0049 16.6 0.9 3.5 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_5 PF14787.6 CDS31777.2 - 0.038 13.7 12.4 0.23 11.2 0.5 3.0 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CDS31778.1 - 2.9e-38 128.3 46.0 1.1e-09 37.9 3.4 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CDS31778.1 - 5.2e-08 32.7 27.3 0.2 11.7 0.3 5.1 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CDS31778.1 - 5.7e-06 26.0 30.3 0.34 10.7 1.2 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 CDS31778.1 - 0.0016 18.1 28.9 0.72 9.6 0.5 5.2 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CDS31778.1 - 0.0079 16.0 38.2 0.085 12.7 1.5 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 CDS31778.1 - 0.047 13.5 3.4 0.047 13.5 3.4 5.4 5 0 0 5 5 5 0 Zinc knuckle Pkinase PF00069.25 CDS31779.2 - 6.8e-62 209.2 0.0 9.4e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31779.2 - 6.2e-30 104.3 0.0 8e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS31779.2 - 0.00023 21.1 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS31779.2 - 0.0017 17.4 0.3 0.0024 16.9 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CDS31779.2 - 0.021 14.4 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CDS31779.2 - 0.1 12.0 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FERM_M PF00373.18 CDS31780.2 - 3.4e-18 66.1 0.0 8.5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CDS31780.2 - 2.8e-14 52.8 0.1 5.5e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.10 CDS31780.2 - 3e-08 33.9 0.0 1.2e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 CDS31780.2 - 0.0041 17.2 2.8 0.011 15.8 2.8 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) RNase_H PF00075.24 CDS31781.2 - 2.3e-11 44.0 0.0 5e-11 43.0 0.0 1.5 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.6 CDS31781.2 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Ion_trans PF00520.31 CDS31782.1 - 3.4e-241 796.1 83.4 4e-63 212.9 4.2 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CDS31782.1 - 2e-30 104.3 0.2 4.1e-30 103.3 0.2 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 CDS31782.1 - 1.8e-28 98.6 0.1 3.5e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 CDS31782.1 - 1.6e-15 56.8 86.0 9.4e-10 37.7 8.8 9.8 6 4 3 9 9 9 6 Polycystin cation channel zf-C2HC_2 PF13913.6 CDS31785.1 - 6.2e-22 77.0 23.0 1.7e-09 37.4 1.3 4.2 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 CDS31785.1 - 3.5e-08 32.9 15.0 1e-07 31.4 4.5 3.7 3 0 0 3 3 3 1 zinc-ribbon domain DUF2318 PF10080.9 CDS31785.1 - 1.7e-06 28.1 5.1 0.0095 16.0 0.0 3.7 4 0 0 4 4 4 2 Predicted membrane protein (DUF2318) zf_UBZ PF18439.1 CDS31785.1 - 1.6e-05 24.4 14.6 0.01 15.4 0.3 4.9 4 1 1 5 5 5 2 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 CDS31785.1 - 6.1e-05 23.7 3.8 6.1e-05 23.7 3.8 2.9 2 2 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 CDS31785.1 - 0.0011 18.9 9.0 0.0011 18.9 9.0 3.6 3 1 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.6 CDS31785.1 - 0.0013 18.0 5.0 0.0013 18.0 5.0 4.0 5 0 0 5 5 4 1 zinc-ribbon domain zf-BED PF02892.15 CDS31785.1 - 0.0054 16.7 3.2 4.1 7.5 0.0 3.5 3 0 0 3 3 3 1 BED zinc finger zf-FPG_IleRS PF06827.14 CDS31785.1 - 0.013 15.4 0.2 0.013 15.4 0.2 3.5 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Cript PF10235.9 CDS31785.1 - 0.026 15.1 1.7 0.026 15.1 1.7 3.3 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT GcpE PF04551.14 CDS31785.1 - 0.058 12.5 0.4 3.4 6.7 0.1 2.1 2 0 0 2 2 2 0 GcpE protein zf-dskA_traR PF01258.17 CDS31785.1 - 0.093 12.7 9.2 34 4.5 2.7 4.3 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger YhfH PF14149.6 CDS31785.1 - 0.16 12.0 9.1 14 5.8 0.2 4.1 4 0 0 4 4 4 0 YhfH-like protein Rad50_zn_hook PF04423.14 CDS31785.1 - 0.22 11.4 1.3 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 CDS31785.1 - 0.38 11.3 15.6 4.7 7.8 0.0 4.8 5 0 0 5 5 4 0 Zinc finger, C2H2 type HypA PF01155.19 CDS31785.1 - 0.57 10.2 14.4 5.2 7.1 2.2 3.7 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 CDS31785.1 - 0.69 10.4 11.0 1.3 9.6 1.8 2.8 2 1 0 2 2 2 0 Cytochrome c3 zf-CSL PF05207.13 CDS31785.1 - 1 9.1 0.1 1 9.1 0.1 2.6 2 1 0 2 2 2 0 CSL zinc finger FYVE PF01363.21 CDS31785.1 - 1.4 9.1 13.0 0.83 9.8 2.8 3.7 3 1 0 3 3 3 0 FYVE zinc finger Ribosomal_L37e PF01907.19 CDS31785.1 - 2.1 8.6 14.8 2.9 8.1 1.5 4.2 4 0 0 4 4 4 0 Ribosomal protein L37e XPA_N PF01286.18 CDS31785.1 - 2.1 8.4 5.6 18 5.5 0.0 3.9 4 0 0 4 4 4 0 XPA protein N-terminal DUF2688 PF10892.8 CDS31785.1 - 2.3 7.7 8.7 1.3 8.5 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) c-SKI_SMAD_bind PF08782.10 CDS31785.1 - 2.8 8.2 0.0 2.8 8.2 0.0 3.1 4 0 0 4 4 3 0 c-SKI Smad4 binding domain UPF0547 PF10571.9 CDS31785.1 - 3.2 7.9 12.8 1.7 8.8 3.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Sgf11 PF08209.11 CDS31785.1 - 3.6 7.2 13.6 6.6 6.4 0.7 4.7 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Nudix_N_2 PF14803.6 CDS31785.1 - 3.9 7.5 14.4 0.47 10.4 0.9 4.3 4 0 0 4 4 4 0 Nudix N-terminal RNA_POL_M_15KD PF02150.16 CDS31785.1 - 7.4 6.5 8.8 64 3.6 0.1 4.0 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-C2H2_4 PF13894.6 CDS31785.1 - 7.7 7.6 23.9 1.4 9.9 0.2 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger PseudoU_synth_1 PF01416.20 CDS31786.2 - 3.8e-12 46.6 0.0 6.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF747 PF05346.11 CDS31788.2 - 1.5e-25 90.4 3.0 2.2e-25 89.8 3.0 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family SCAN PF02023.17 CDS31788.2 - 0.01 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 SCAN domain Peptidase_C2 PF00648.21 CDS31788.2 - 0.14 11.1 0.3 0.23 10.4 0.3 1.2 1 0 0 1 1 1 0 Calpain family cysteine protease Peptidase_M28 PF04389.17 CDS31790.1 - 8.9e-34 116.9 0.0 1.5e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SIR2 PF02146.17 CDS31792.2 - 1.3e-27 96.9 0.1 4.3e-27 95.2 0.1 1.7 1 1 0 1 1 1 1 Sir2 family Med27 PF11571.8 CDS31792.2 - 0.015 15.6 0.1 0.031 14.6 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 27 PNTB PF02233.16 CDS31792.2 - 0.046 12.6 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit zinc_ribbon_4 PF13717.6 CDS31792.2 - 0.1 12.5 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 CDS31792.2 - 0.17 11.7 0.2 0.17 11.7 0.2 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 CDS31792.2 - 1 8.9 4.6 2.7 7.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-ribbon Xpo1 PF08389.12 CDS31793.2 - 6.9e-23 81.4 2.6 3.2e-22 79.2 1.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein Hyccin PF09790.9 CDS31794.1 - 1.2e-11 44.3 4.4 5.2e-06 25.8 0.1 3.2 3 0 0 3 3 3 3 Hyccin EF-hand_1 PF00036.32 CDS31795.1 - 1.6e-11 42.9 0.5 8.4e-05 21.8 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDS31795.1 - 5.9e-11 42.7 0.0 0.00017 21.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS31795.1 - 1.4e-10 40.2 0.1 0.00016 21.3 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 CDS31795.1 - 3.2e-09 37.0 0.0 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS31795.1 - 4.7e-05 23.1 0.1 0.13 12.2 0.1 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS31795.1 - 0.02 14.4 1.1 0.44 10.1 0.2 2.6 2 0 0 2 2 2 0 EF hand fn3 PF00041.21 CDS31796.1 - 1.1e-18 67.3 7.5 3.3e-08 33.8 0.9 4.4 4 0 0 4 4 4 3 Fibronectin type III domain WAP PF00095.21 CDS31796.1 - 2.4e-08 34.2 11.1 2.4e-08 34.2 11.1 3.2 3 0 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pur_ac_phosph_N PF16656.5 CDS31796.1 - 0.00032 21.2 0.4 0.042 14.4 0.1 3.3 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain ASH PF15780.5 CDS31796.1 - 0.085 13.1 0.8 0.25 11.5 0.2 2.1 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4336 PF14234.6 CDS31797.1 - 0.017 14.3 0.1 0.024 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Cadherin PF00028.17 CDS31799.1 - 1.9e-60 201.3 2.6 2.4e-13 50.3 0.1 8.0 7 2 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 CDS31799.1 - 0.00091 19.2 6.9 2.4 8.2 0.1 6.0 6 0 0 6 6 6 1 Cadherin-like RET_CLD1 PF17756.1 CDS31799.1 - 0.015 15.6 0.2 31 4.9 0.0 4.3 5 0 0 5 5 5 0 RET Cadherin like domain 1 TMEM154 PF15102.6 CDS31799.1 - 0.034 14.1 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2807 PF10988.8 CDS31800.1 - 0.033 14.0 0.3 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain RIO1 PF01163.22 CDS31801.1 - 3.5e-33 114.8 2.3 8.7e-25 87.4 0.0 2.5 3 0 0 3 3 3 2 RIO1 family Rio2_N PF09202.11 CDS31801.1 - 1.3e-23 83.0 0.1 2.6e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 CDS31801.1 - 0.00014 21.3 0.0 0.00064 19.1 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS31801.1 - 0.0099 15.8 1.0 1.1 9.1 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family FAM176 PF14851.6 CDS31801.1 - 0.59 9.8 9.3 1.4 8.6 9.3 1.6 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 CDS31801.1 - 1 7.6 17.1 1.6 6.9 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 CDS31801.1 - 2.6 6.0 10.4 3.7 5.5 10.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 CDS31802.1 - 5.6e-28 97.9 37.8 6.4e-20 71.4 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 CDS31802.1 - 1.5 8.5 11.7 0.24 11.2 4.9 2.8 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) Ribosomal_L22e PF01776.17 CDS31803.1 - 1.9e-39 134.4 3.9 2.4e-39 134.1 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SPC25 PF06703.11 CDS31806.1 - 6e-41 139.9 0.9 6.9e-41 139.7 0.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BOFC_N PF08977.10 CDS31806.1 - 0.029 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal ubiquitin PF00240.23 CDS31807.1 - 2.2e-34 117.0 0.3 2.8e-34 116.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDS31807.1 - 3.9e-28 97.1 13.2 6e-28 96.5 13.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDS31807.1 - 3.2e-16 58.9 0.3 4.5e-16 58.4 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDS31807.1 - 2.3e-05 24.7 0.1 8.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDS31807.1 - 0.0079 16.5 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDS31807.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDS31807.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS31807.1 - 0.072 13.1 0.6 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Fer2_3 PF13085.6 CDS31807.1 - 0.2 11.7 2.2 0.92 9.5 1.7 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Aldo_ket_red PF00248.21 CDS31808.1 - 2.1e-05 23.8 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family CAT PF00302.18 CDS31808.1 - 0.054 13.4 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase HipN PF18253.1 CDS31809.1 - 2.4e-14 52.7 0.3 1.8e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 Hsp70-interacting protein N N-terminal domain TPR_1 PF00515.28 CDS31809.1 - 1.3e-11 43.8 5.6 9.9e-07 28.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 CDS31809.1 - 5.4e-10 39.1 6.0 8.8e-10 38.4 5.2 1.8 2 0 0 2 2 1 1 STI1 domain TPR_9 PF13371.6 CDS31809.1 - 2.4e-07 30.8 0.5 0.0002 21.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS31809.1 - 1.3e-06 28.0 13.5 0.00015 21.6 0.0 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS31809.1 - 0.00029 21.0 1.1 1.1 9.8 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS31809.1 - 0.0013 18.4 4.7 0.0035 17.0 0.1 3.2 1 1 2 3 3 3 1 TPR repeat TPR_19 PF14559.6 CDS31809.1 - 0.0034 17.9 1.1 0.0034 17.9 1.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31809.1 - 0.01 16.6 3.6 0.13 13.2 0.1 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31809.1 - 0.023 14.9 6.5 0.15 12.3 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS31809.1 - 0.082 13.1 2.4 0.63 10.3 1.4 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDS31809.1 - 0.15 12.8 9.4 0.18 12.4 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31809.1 - 1.2 9.5 4.7 0.81 10.0 0.3 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 CDS31809.1 - 1.2 8.8 12.6 0.52 10.1 5.6 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TPR_6 PF13174.6 CDS31809.1 - 1.6 9.6 0.0 1.6 9.6 0.0 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 CDS31810.1 - 5.4e-24 83.7 0.9 1.3e-23 82.5 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_5 PF07728.14 CDS31811.2 - 3.1e-106 351.2 0.0 1.1e-23 83.8 0.0 8.0 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDS31811.2 - 6.8e-36 122.7 0.4 1.1e-10 41.6 0.0 5.9 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 CDS31811.2 - 5e-25 87.6 0.0 5.6e-24 84.2 0.0 2.9 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_16 PF13191.6 CDS31811.2 - 2.6e-23 83.2 8.0 0.0021 18.5 1.1 8.5 6 1 0 6 6 6 5 AAA ATPase domain AAA PF00004.29 CDS31811.2 - 4.8e-22 78.8 0.1 5.1e-05 23.7 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDS31811.2 - 7.6e-21 74.4 0.0 2.2e-05 24.0 0.0 6.4 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_22 PF13401.6 CDS31811.2 - 6.5e-20 71.8 0.4 2.1e-05 24.8 0.0 6.8 7 0 0 7 7 6 4 AAA domain AAA_3 PF07726.11 CDS31811.2 - 2.1e-17 63.2 0.0 4.8e-09 36.2 0.0 5.7 5 1 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CDS31811.2 - 1.4e-16 60.6 0.0 0.0014 18.7 0.0 7.1 6 0 0 6 6 5 2 Dynein heavy chain region D6 P-loop domain AAA_30 PF13604.6 CDS31811.2 - 3.3e-14 53.0 0.0 0.055 13.2 0.0 6.5 7 0 0 7 7 6 3 AAA domain Sigma54_activat PF00158.26 CDS31811.2 - 1.2e-12 47.8 0.0 0.019 14.6 0.0 5.4 6 0 0 6 6 5 3 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CDS31811.2 - 3.5e-11 43.3 1.0 2.2 8.2 0.0 6.5 6 0 0 6 6 6 2 RsgA GTPase TsaE PF02367.17 CDS31811.2 - 2e-10 40.8 0.9 0.31 11.1 0.0 6.1 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_8 PF12780.7 CDS31811.2 - 1e-09 38.1 0.1 0.15 11.3 0.0 6.1 5 1 0 5 5 5 2 P-loop containing dynein motor region D4 AAA_29 PF13555.6 CDS31811.2 - 4.8e-09 35.8 0.4 0.44 10.3 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDS31811.2 - 1.5e-08 34.7 0.0 0.16 12.0 0.0 6.1 7 0 0 7 7 6 1 AAA domain Sigma54_activ_2 PF14532.6 CDS31811.2 - 2.2e-08 34.3 0.1 0.012 15.7 0.0 4.8 5 0 0 5 5 3 2 Sigma-54 interaction domain DUF815 PF05673.13 CDS31811.2 - 3.3e-08 33.0 3.1 1 8.5 0.1 6.2 6 0 0 6 6 6 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDS31811.2 - 7.3e-08 33.0 22.4 0.057 13.9 0.0 7.9 10 0 0 10 10 6 3 ABC transporter Rad17 PF03215.15 CDS31811.2 - 3.2e-07 30.4 1.3 0.049 13.5 0.0 4.5 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_6 PF12774.7 CDS31811.2 - 3.8e-07 29.4 0.2 0.93 8.4 0.0 6.6 8 0 0 8 8 8 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CDS31811.2 - 4.1e-07 30.6 5.8 2.2 8.8 0.0 7.1 6 0 0 6 6 5 2 AAA domain RNA_helicase PF00910.22 CDS31811.2 - 6.4e-07 29.7 0.2 6.7 7.1 0.0 5.8 5 0 0 5 5 5 0 RNA helicase NACHT PF05729.12 CDS31811.2 - 1.4e-06 28.3 1.2 1.4 8.8 0.0 5.1 4 0 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.21 CDS31811.2 - 2e-06 27.3 4.3 3.9 6.8 0.2 7.7 8 2 0 8 8 7 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDS31811.2 - 1.5e-05 24.6 1.9 7.3 6.1 0.0 6.3 6 0 0 6 6 6 0 AAA domain AAA_19 PF13245.6 CDS31811.2 - 3.2e-05 24.3 0.1 1.7 9.0 0.0 4.8 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 CDS31811.2 - 3.8e-05 23.1 0.2 0.94 8.7 0.0 5.0 6 0 0 6 6 5 1 Zeta toxin IstB_IS21 PF01695.17 CDS31811.2 - 5.5e-05 23.0 0.7 3.6 7.3 0.0 5.4 6 0 0 6 6 5 1 IstB-like ATP binding protein SRP54 PF00448.22 CDS31811.2 - 6.8e-05 22.6 0.2 5.8 6.5 0.0 5.3 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain Roc PF08477.13 CDS31811.2 - 0.00011 22.4 1.5 26 5.0 0.0 5.9 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CDS31811.2 - 0.00014 22.1 4.1 0.41 10.9 0.0 5.4 5 0 0 5 5 5 1 AAA domain VWA PF00092.28 CDS31811.2 - 0.00018 21.8 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PduV-EutP PF10662.9 CDS31811.2 - 0.00019 21.2 1.5 0.21 11.3 0.0 4.9 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 CDS31811.2 - 0.00038 20.2 0.6 7.6 6.3 0.0 5.1 6 0 0 6 6 5 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CDS31811.2 - 0.00045 20.0 0.0 12 5.6 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDS31811.2 - 0.00048 20.3 1.1 0.92 9.7 0.0 5.2 6 0 0 6 6 4 1 AAA domain Viral_helicase1 PF01443.18 CDS31811.2 - 0.0011 18.7 1.3 1.6 8.4 0.0 4.8 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 CDS31811.2 - 0.0022 17.4 0.0 1.9 7.8 0.0 4.4 5 0 0 5 5 5 1 Bacterial TniB protein MMR_HSR1 PF01926.23 CDS31811.2 - 0.0027 17.8 0.1 31 4.7 0.0 5.2 5 0 0 5 5 5 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDS31811.2 - 0.0054 16.6 1.0 59 3.3 0.0 4.9 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein FRB_dom PF08771.11 CDS31811.2 - 0.013 15.9 4.2 5.7 7.4 0.1 3.8 3 0 0 3 3 2 0 FKBP12-rapamycin binding domain TIP49 PF06068.13 CDS31811.2 - 0.024 13.8 0.1 0.33 10.1 0.0 2.9 4 0 0 4 4 3 0 TIP49 P-loop domain VWA_2 PF13519.6 CDS31811.2 - 0.031 14.9 0.1 0.11 13.2 0.1 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain ATPase PF06745.13 CDS31811.2 - 0.094 12.1 0.1 3 7.1 0.0 3.1 3 0 0 3 3 3 0 KaiC STAT_alpha PF01017.20 CDS31811.2 - 0.14 12.0 2.7 30 4.5 0.2 4.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain dNK PF01712.19 CDS31811.2 - 0.2 11.5 1.5 61 3.4 0.0 4.3 5 0 0 5 5 4 0 Deoxynucleoside kinase cobW PF02492.19 CDS31811.2 - 0.42 10.2 2.4 29 4.2 0.0 4.0 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain MutL_C PF08676.11 CDS31812.1 - 2.6e-28 98.6 0.0 5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CDS31812.1 - 1.3e-14 53.9 0.0 4.4e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDS31812.1 - 2.8e-11 43.4 0.4 7.1e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDS31812.1 - 5.4e-05 23.7 0.2 0.00012 22.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 CDS31813.1 - 2.1e-18 66.3 11.7 0.00019 22.1 0.1 8.8 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31813.1 - 5.3e-09 36.3 1.1 0.25 11.7 0.0 7.6 5 3 4 10 10 10 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDS31813.1 - 8.1e-05 21.5 0.5 0.68 8.6 0.0 3.6 2 1 1 3 3 3 2 Nup133 N terminal like MPS2 PF17060.5 CDS31813.1 - 0.00039 19.8 10.5 0.00039 19.8 10.5 4.0 1 1 3 4 4 4 1 Monopolar spindle protein 2 ATG16 PF08614.11 CDS31813.1 - 0.0072 16.6 17.8 0.0072 16.6 17.8 5.0 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 CDS31813.1 - 0.011 15.8 7.1 0.011 15.8 7.1 4.1 3 1 1 4 4 4 0 Laminin Domain II E2R135 PF11570.8 CDS31813.1 - 0.19 12.0 10.4 0.067 13.5 6.9 2.1 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Baculo_PEP_C PF04513.12 CDS31813.1 - 0.47 10.5 5.3 5.9 6.9 0.1 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cadherin PF00028.17 CDS31814.1 - 4.3e-66 219.4 0.0 1.8e-11 44.3 0.1 8.8 8 2 0 8 8 8 7 Cadherin domain Cadherin_2 PF08266.12 CDS31814.1 - 3.6e-10 39.5 0.0 0.00014 21.7 0.0 5.0 6 0 0 6 6 6 2 Cadherin-like Cadherin_3 PF16184.5 CDS31814.1 - 0.0035 17.3 1.4 1.1 9.2 0.0 4.2 5 0 0 5 5 5 1 Cadherin-like DUF2958 PF11171.8 CDS31814.1 - 0.042 14.1 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) MAPEG PF01124.18 CDS31815.1 - 3.8e-18 65.6 0.6 4.6e-18 65.4 0.6 1.1 1 0 0 1 1 1 1 MAPEG family Caa3_CtaG PF09678.10 CDS31815.1 - 0.049 13.1 1.6 0.05 13.1 0.7 1.5 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) MAPEG PF01124.18 CDS31816.1 - 5.4e-11 42.5 0.1 2.6e-10 40.3 0.1 1.8 1 1 0 1 1 1 1 MAPEG family LSM PF01423.22 CDS31817.1 - 2.5e-14 52.7 0.4 3.1e-14 52.4 0.4 1.1 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.28 CDS31818.1 - 2.2e-26 93.7 0.1 3.5e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mtp PF03821.16 CDS31819.1 - 4.5e-10 39.5 13.3 5.4e-05 22.9 0.8 3.3 2 1 1 3 3 3 3 Golgi 4-transmembrane spanning transporter DUF4728 PF15860.5 CDS31819.1 - 0.11 13.2 0.6 0.11 13.2 0.6 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4728) EIF4E-T PF10477.9 CDS31822.1 - 0.0096 14.8 4.0 0.011 14.6 4.0 1.0 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RNase_H PF00075.24 CDS31823.1 - 0.003 17.7 0.0 0.0075 16.5 0.0 1.6 2 0 0 2 2 2 1 RNase H MRP-S27 PF10037.9 CDS31824.1 - 9.9e-61 205.7 2.1 1.4e-60 205.2 2.1 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 DUF1819 PF08849.11 CDS31824.1 - 0.15 11.9 4.0 2.7 7.8 0.2 3.1 3 0 0 3 3 3 0 Putative inner membrane protein (DUF1819) DUF501 PF04417.12 CDS31824.1 - 0.51 10.1 1.7 0.67 9.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF3510 PF12022.8 CDS31824.1 - 4.2 7.8 6.8 6.1 7.2 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) Vps35 PF03635.17 CDS31825.1 - 0.021 13.4 0.4 0.021 13.4 0.4 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Cohesin_load PF10345.9 CDS31826.1 - 2.2e-56 191.6 0.0 2.6e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_MalT PF17874.1 CDS31826.1 - 1.1e-06 28.2 8.7 0.0016 17.8 0.1 3.5 2 1 1 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 CDS31826.1 - 3.6e-05 23.6 5.2 5.4 7.4 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31826.1 - 0.0024 18.0 0.5 18 5.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat HemY_N PF07219.13 CDS31826.1 - 0.017 15.3 2.0 1.3 9.2 0.1 3.8 4 0 0 4 4 4 0 HemY protein N-terminus TPR_12 PF13424.6 CDS31826.1 - 0.37 11.1 10.2 1.4 9.2 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31826.1 - 1.5 9.8 4.6 1.1e+02 4.1 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 CDS31827.1 - 1.6e-70 237.5 0.0 3.5e-70 236.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31827.1 - 9.1e-47 159.5 0.0 1.8e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDS31827.1 - 4.1e-12 46.3 2.0 1.4e-11 44.6 0.1 2.6 2 1 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 CDS31827.1 - 4.5e-09 36.0 0.0 1.9e-07 30.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDS31827.1 - 1.9e-08 33.5 0.2 5.9e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDS31827.1 - 0.0014 17.6 0.2 0.0052 15.8 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDS31827.1 - 0.018 15.0 0.0 0.35 10.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDS31827.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDS31827.1 - 0.044 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Alg6_Alg8 PF03155.15 CDS31829.1 - 1.5e-131 439.8 32.6 1.7e-131 439.5 32.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ADP_ribosyl_GH PF03747.14 CDS31830.1 - 3.8e-45 154.8 0.0 4.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase UPF0139 PF03669.13 CDS31831.1 - 1.3e-27 95.5 0.0 1.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) PepSY_TM PF03929.16 CDS31831.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 PepSY-associated TM region MtN3_slv PF03083.16 CDS31831.1 - 0.036 14.1 2.5 0.93 9.6 0.8 2.1 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange RNase_T PF00929.24 CDS31832.1 - 9e-19 68.6 0.0 3.6e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Exonuclease MOZ_SAS PF01853.18 CDS31833.1 - 7.7e-80 266.8 0.2 1.1e-79 266.3 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDS31833.1 - 9.7e-23 79.5 5.4 9.7e-23 79.5 5.4 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDS31833.1 - 8.7e-16 57.6 0.3 2e-15 56.4 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CDS31833.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Agenet PF05641.12 CDS31833.1 - 0.0034 17.8 0.0 0.0086 16.5 0.0 1.7 1 0 0 1 1 1 1 Agenet domain Acetyltransf_1 PF00583.25 CDS31833.1 - 0.04 14.2 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Kunitz_BPTI PF00014.23 CDS31834.1 - 1e-81 269.0 63.8 6.4e-19 67.9 7.5 6.2 6 0 0 6 6 6 6 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CDS31835.1 - 1.3e-245 793.9 161.1 2.3e-20 72.6 4.4 13.1 13 0 0 13 13 13 13 Kunitz/Bovine pancreatic trypsin inhibitor domain CDI PF02234.19 CDS31835.1 - 0.032 14.4 0.5 27 5.0 0.0 5.5 7 0 0 7 7 7 0 Cyclin-dependent kinase inhibitor Nsp3_PL2pro PF12124.8 CDS31835.1 - 0.47 10.3 2.7 13 5.7 0.0 3.9 4 0 0 4 4 4 0 Coronavirus polyprotein cleavage domain MAAL_N PF05034.13 CDS31835.1 - 1.1 8.8 12.3 61 3.2 0.0 6.6 8 0 0 8 8 8 0 Methylaspartate ammonia-lyase N-terminus HTH_AsnC-type PF13404.6 CDS31836.1 - 3.9e-05 23.4 0.2 4.8e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 CDS31836.1 - 0.0001 21.8 0.2 0.00013 21.4 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 CDS31836.1 - 0.00038 20.3 0.2 0.00051 19.9 0.2 1.2 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 CDS31836.1 - 0.0041 16.9 0.1 0.0059 16.4 0.1 1.3 1 0 0 1 1 1 1 HTH DNA binding domain MarR PF01047.22 CDS31836.1 - 0.0073 16.2 0.1 0.0097 15.8 0.1 1.1 1 0 0 1 1 1 1 MarR family MoaE PF02391.17 CDS31836.1 - 0.012 15.9 0.0 0.014 15.6 0.0 1.0 1 0 0 1 1 1 0 MoaE protein HTH_20 PF12840.7 CDS31836.1 - 0.02 14.9 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CMS1 PF14617.6 CDS31836.1 - 0.046 13.0 0.1 0.057 12.7 0.1 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sigma70_r4 PF04545.16 CDS31836.1 - 0.051 13.1 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_1 PF00126.27 CDS31836.1 - 0.052 13.5 0.1 0.077 13.0 0.1 1.4 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 CDS31836.1 - 0.053 13.5 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 CDS31836.1 - 0.072 13.0 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 CDS31836.1 - 0.086 12.7 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 CDS31836.1 - 0.097 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Use1 PF09753.9 CDS31837.1 - 3.2e-32 112.2 0.5 4.3e-32 111.8 0.5 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 FRB_dom PF08771.11 CDS31837.1 - 0.5 10.8 3.5 0.17 12.3 0.8 1.6 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Synaptobrevin PF00957.21 CDS31837.1 - 1.2 9.0 3.2 0.91 9.4 0.7 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF1201 PF06716.11 CDS31837.1 - 3.1 7.9 6.8 6.3 6.9 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) G-alpha PF00503.20 CDS31838.1 - 4.7e-45 154.3 5.6 3.5e-44 151.4 5.6 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS31838.1 - 1.5e-05 24.5 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_5 PF07728.14 CDS31838.1 - 0.0049 16.9 0.4 2.2 8.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS31838.1 - 0.12 12.7 0.0 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain CitMHS PF03600.16 CDS31840.1 - 0.019 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter DUF4064 PF13273.6 CDS31840.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 CDS31840.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SDF PF00375.18 CDS31841.1 - 6.5e-71 239.4 34.2 8.6e-71 239.0 34.2 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family UCH PF00443.29 CDS31841.1 - 1.7e-21 76.9 1.5 2.1e-21 76.6 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS31841.1 - 3.1e-18 66.5 0.5 3.1e-18 66.5 0.5 2.1 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Proteasome PF00227.26 CDS31842.1 - 1.2e-53 181.5 0.2 1.5e-53 181.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDS31842.1 - 3.6e-14 52.1 0.0 6.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 CDS31843.1 - 1.4e-09 37.7 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31843.1 - 0.0045 16.3 0.1 0.0063 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuclease_3 PF00636.26 CDS31844.1 - 1e-41 141.8 0.4 6.2e-22 78.2 0.1 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDS31844.1 - 2.6e-37 127.8 0.1 1.6e-16 60.6 0.0 3.4 2 1 1 3 3 3 3 Ribonuclease-III-like dsrm PF00035.26 CDS31844.1 - 3.7e-10 40.4 0.0 1.1e-09 38.8 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif SOAR PF16533.5 CDS31845.1 - 1.6e-34 117.9 1.5 1.6e-34 117.9 1.5 1.6 2 0 0 2 2 2 1 STIM1 Orai1-activating region SAM_2 PF07647.17 CDS31845.1 - 3.2e-11 43.1 0.6 1.1e-10 41.5 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS31845.1 - 3.8e-08 33.6 0.0 8.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_30 PF13556.6 CDS31845.1 - 0.0023 17.7 0.0 0.0087 15.8 0.0 2.0 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Med2 PF11214.8 CDS31845.1 - 0.019 15.1 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 SecE PF00584.20 CDS31846.1 - 4.2e-13 49.0 0.1 4.9e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DEAD PF00270.29 CDS31847.1 - 2.4e-49 167.5 0.0 3.9e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31847.1 - 6e-33 113.5 0.0 8.4e-32 109.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CDS31847.1 - 0.037 12.8 0.0 1.3 7.7 0.0 2.9 3 1 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UbiA PF01040.18 CDS31848.1 - 2.4e-48 164.6 13.1 3.1e-48 164.3 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Guanylate_cyc PF00211.20 CDS31849.1 - 1.5e-112 373.4 0.0 1.1e-55 188.1 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CDS31849.1 - 1.8e-52 178.2 0.0 6.3e-31 107.6 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CDS31849.1 - 5.1e-46 157.2 0.0 2.3e-28 99.3 0.0 3.3 2 1 1 3 3 3 3 Protein kinase domain HNOBA PF07701.14 CDS31849.1 - 3.8e-05 23.2 3.7 0.015 14.7 0.3 2.4 2 0 0 2 2 2 2 Heme NO binding associated DUF2475 PF10629.9 CDS31849.1 - 0.00096 19.3 0.5 0.14 12.4 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2475) ANF_receptor PF01094.28 CDS31849.1 - 0.0014 17.8 0.2 0.6 9.2 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region RE_ApaLI PF09499.10 CDS31849.1 - 0.042 13.6 0.2 6.1 6.5 0.1 2.4 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease DUF3719 PF12516.8 CDS31849.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) RabGAP-TBC PF00566.18 CDS31850.1 - 2.2e-54 184.4 0.1 2.2e-54 184.4 0.1 2.2 1 1 2 3 3 3 1 Rab-GTPase-TBC domain WD40 PF00400.32 CDS31851.1 - 1.8e-62 205.8 20.2 8.9e-10 39.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS31851.1 - 3.8e-23 81.6 0.3 0.0001 22.5 0.0 6.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS31851.1 - 3.1e-10 39.3 1.1 0.017 13.8 0.1 5.3 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CDS31851.1 - 1.4e-09 38.1 0.0 0.00027 20.9 0.0 3.5 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDS31851.1 - 1.3e-06 28.0 0.0 0.019 14.3 0.0 3.2 1 1 2 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 CDS31851.1 - 0.00039 19.5 3.0 0.7 8.8 0.6 4.4 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CDS31851.1 - 0.0013 17.7 1.0 1.4 7.8 0.0 4.3 1 1 4 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CDS31851.1 - 0.012 14.0 0.0 0.8 7.9 0.0 2.6 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SBD PF17882.1 CDS31851.1 - 0.018 14.9 0.1 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain VID27 PF08553.10 CDS31851.1 - 0.019 14.1 0.0 0.94 8.5 0.0 2.6 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain TRAM_LAG1_CLN8 PF03798.16 CDS31853.1 - 1.9e-15 57.2 9.1 2.2e-15 56.9 9.1 1.1 1 0 0 1 1 1 1 TLC domain DUF1360 PF07098.11 CDS31853.1 - 0.04 13.9 2.3 0.061 13.3 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Pkinase PF00069.25 CDS31855.1 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31855.1 - 7.3e-35 120.5 0.0 2e-34 119.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS31855.1 - 1.1e-05 24.6 0.2 2e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDS31855.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CDS31855.1 - 0.0036 16.7 0.0 0.18 11.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CDS31855.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDS31855.1 - 0.089 12.7 0.0 0.91 9.4 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDS31855.1 - 0.11 12.0 0.4 0.22 11.1 0.4 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.16 CDS31856.1 - 3.7e-22 78.7 42.6 1.1e-15 57.4 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CDS31856.1 - 0.0015 17.0 5.0 0.0035 15.8 1.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector DUF3810 PF12725.7 CDS31856.1 - 0.23 10.8 4.2 0.43 9.9 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) NAPRTase PF04095.16 CDS31857.1 - 1.1e-65 221.6 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 CDS31857.1 - 0.0039 17.6 0.0 0.0096 16.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) Ldh_1_C PF02866.18 CDS31858.1 - 1.1e-47 162.0 0.0 1.6e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDS31858.1 - 3.5e-38 130.9 0.0 5.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CDS31858.1 - 0.00068 20.1 0.5 0.0091 16.4 0.3 2.6 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CDS31858.1 - 0.038 13.5 0.2 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Retro_M PF02813.14 CDS31858.1 - 0.15 12.5 0.1 0.4 11.1 0.1 1.7 1 0 0 1 1 1 0 Retroviral M domain Ldh_1_C PF02866.18 CDS31859.1 - 4.2e-51 173.2 0.0 9e-51 172.1 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDS31859.1 - 7.4e-46 155.7 0.0 1.3e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CDS31859.1 - 0.0078 15.8 0.3 0.3 10.6 0.1 2.3 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 CDS31859.1 - 0.016 15.6 0.1 0.057 13.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CDS31859.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family INTS2 PF14750.6 CDS31860.1 - 3.5e-130 435.5 21.5 1.8e-128 429.8 21.5 2.7 1 1 0 1 1 1 1 Integrator complex subunit 2 Rib_5-P_isom_A PF06026.14 CDS31861.1 - 7.2e-58 195.0 0.0 9e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 CDS31861.1 - 0.039 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain SpoVS PF04232.12 CDS31861.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) DNA_methylase PF00145.17 CDS31862.1 - 2.7e-39 135.5 0.0 7.9e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Cullin PF00888.22 CDS31863.1 - 7.7e-157 523.6 11.9 1e-156 523.2 11.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS31863.1 - 7.1e-28 96.4 1.6 2.6e-27 94.6 1.6 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain MHC_I_3 PF16497.5 CDS31863.1 - 0.03 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 MHC-I family domain Cullin PF00888.22 CDS31864.1 - 7.3e-83 279.2 14.5 9.9e-83 278.8 14.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS31864.1 - 3.2e-15 55.9 0.2 1.8e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain MarR PF01047.22 CDS31864.1 - 0.089 12.7 1.0 0.44 10.5 0.4 2.2 2 0 0 2 2 2 0 MarR family CaMBD PF02888.16 CDS31864.1 - 0.16 12.2 1.8 19 5.6 0.0 2.8 2 0 0 2 2 2 0 Calmodulin binding domain Cullin PF00888.22 CDS31865.1 - 1.2e-128 430.5 20.6 1.7e-128 430.0 20.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDS31865.1 - 8.2e-23 80.2 0.0 3.6e-22 78.2 0.0 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain Pkinase PF00069.25 CDS31865.1 - 1.3e-14 54.2 0.0 3.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31865.1 - 1.3e-07 31.2 0.0 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Rrf2 PF02082.20 CDS31865.1 - 0.12 12.7 0.2 0.37 11.2 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulator Slx4 PF09494.10 CDS31866.1 - 1.3e-09 37.8 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease BTB PF00651.31 CDS31866.1 - 0.0086 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mut7-C PF01927.16 CDS31866.1 - 0.37 10.9 1.3 0.75 9.9 1.3 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain zinc-ribbons_6 PF07191.12 CDS31866.1 - 0.87 9.6 3.6 1.7 8.7 3.6 1.4 1 0 0 1 1 1 0 zinc-ribbons TPR_2 PF07719.17 CDS31867.1 - 9.7e-05 22.2 2.1 0.00029 20.7 0.3 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS31867.1 - 0.001 19.7 0.2 0.99 10.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31867.1 - 0.0011 19.2 0.5 0.2 12.0 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS31867.1 - 0.014 15.2 0.2 0.089 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31867.1 - 0.046 13.8 0.0 1.3 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_primase_S PF01896.19 CDS31868.1 - 1.4e-47 162.0 0.3 2.1e-47 161.5 0.3 1.2 1 0 0 1 1 1 1 DNA primase small subunit PseudoU_synth_1 PF01416.20 CDS31869.1 - 6e-25 87.8 0.0 8.3e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase FKBP_C PF00254.28 CDS31870.1 - 2.4e-15 56.6 0.0 2.6e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CDS31870.1 - 6.5e-15 54.2 6.2 7.6e-08 31.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS31870.1 - 2e-12 46.2 1.1 1.4e-06 27.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS31870.1 - 8.2e-09 35.0 1.1 3.8e-06 26.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS31870.1 - 1.6e-06 28.3 0.1 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS31870.1 - 1.6e-05 25.3 0.0 0.011 16.5 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDS31870.1 - 0.0012 19.3 0.1 0.16 12.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS31870.1 - 0.0023 18.4 0.1 0.032 14.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS31870.1 - 0.0051 16.5 0.8 0.034 13.8 0.0 2.5 3 0 0 3 3 3 1 TPR repeat FKBP_N_2 PF18023.1 CDS31870.1 - 0.0077 16.3 0.0 0.058 13.5 0.0 2.3 2 0 0 2 2 2 1 BDBT FKBP like N-terminal TPR_17 PF13431.6 CDS31870.1 - 0.0094 16.3 2.5 5.1 7.7 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS31870.1 - 0.029 14.6 2.3 0.092 13.0 2.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CDS31870.1 - 0.031 14.3 0.6 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CDS31870.1 - 0.067 13.9 0.0 4.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS31870.1 - 0.087 12.9 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat Connexin50 PF03509.14 CDS31870.1 - 0.097 13.5 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Gap junction alpha-8 protein (Cx50) C12orf66_like PF09404.10 CDS31871.1 - 5.4e-16 58.5 5.1 6.7e-15 54.9 5.1 2.0 1 1 0 1 1 1 1 KICSTOR complex C12orf66 like Aminotran_1_2 PF00155.21 CDS31872.1 - 8.3e-63 212.7 0.0 1e-62 212.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDS31872.1 - 0.00046 19.3 0.0 0.0009 18.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDS31872.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDS31872.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Acetyltransf_1 PF00583.25 CDS31873.1 - 1.9e-18 66.8 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS31873.1 - 2.8e-12 46.9 0.1 4.8e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS31873.1 - 3.6e-11 43.1 0.0 5.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDS31873.1 - 7.7e-10 38.6 0.0 1.7e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 CDS31873.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDS31873.1 - 0.00012 22.7 0.0 0.00018 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDS31873.1 - 0.00043 20.3 0.0 0.00081 19.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDS31873.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CDS31873.1 - 0.013 15.7 0.1 0.018 15.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CDS31873.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Ig_3 PF13927.6 CDS31874.1 - 1.7e-47 159.9 7.4 8.9e-07 29.4 0.0 10.6 10 1 0 10 10 10 7 Immunoglobulin domain I-set PF07679.16 CDS31874.1 - 3e-35 120.1 0.0 8.7e-08 32.1 0.0 9.8 9 2 0 9 9 9 6 Immunoglobulin I-set domain C2-set_2 PF08205.12 CDS31874.1 - 5.6e-25 87.2 0.6 1.5e-07 31.4 0.0 8.3 9 0 0 9 9 9 6 CD80-like C2-set immunoglobulin domain ig PF00047.25 CDS31874.1 - 2e-23 82.3 0.7 0.0036 17.4 0.0 8.6 9 0 0 9 9 9 5 Immunoglobulin domain Ig_2 PF13895.6 CDS31874.1 - 9.1e-23 80.4 10.9 0.00028 21.2 0.0 11.1 11 1 0 11 11 11 6 Immunoglobulin domain V-set PF07686.17 CDS31874.1 - 8.2e-19 67.8 8.0 1.7e-07 31.4 0.0 8.5 7 3 0 7 7 7 3 Immunoglobulin V-set domain fn3 PF00041.21 CDS31874.1 - 2.8e-08 34.0 0.1 7.7e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Arylsulfotran_N PF17425.2 CDS31874.1 - 0.036 14.1 0.2 0.097 12.7 0.2 1.8 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain Ig_6 PF18452.1 CDS31874.1 - 0.043 13.4 0.0 25 4.5 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin domain Izumo-Ig PF16706.5 CDS31874.1 - 0.062 13.4 0.1 3.2 7.9 0.0 3.4 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain Insulin_TMD PF17870.1 CDS31874.1 - 0.13 12.3 3.1 0.36 10.9 3.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SAM_1 PF00536.30 CDS31875.2 - 0.014 15.8 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Homeodomain PF00046.29 CDS31876.1 - 1.7e-23 82.2 6.0 2.9e-23 81.5 6.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS31876.1 - 0.00094 19.0 0.1 0.00094 19.0 0.1 2.3 3 0 0 3 3 3 1 Homeobox KN domain Auxin_canalis PF05703.11 CDS31876.1 - 0.78 9.6 3.6 4.6 7.1 0.5 2.2 2 0 0 2 2 2 0 Auxin canalisation C1q PF00386.21 CDS31877.1 - 1.9e-21 76.6 0.0 2.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CDS31877.1 - 2.5e-05 23.9 11.1 4.1e-05 23.3 11.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) BclA_C PF18573.1 CDS31877.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 BclA C-terminal domain Pkinase PF00069.25 CDS31878.1 - 4.3e-35 121.3 0.0 5.2e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31878.1 - 6.2e-15 55.2 0.0 7.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS31878.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDS31878.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 CDS31879.1 - 5e-13 48.4 0.0 1.7e-09 36.8 0.1 2.1 2 0 0 2 2 2 2 Actin Actin_micro PF17003.5 CDS31879.1 - 4.5e-06 26.1 0.2 0.00034 19.9 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family UQ_con PF00179.26 CDS31880.1 - 1.9e-20 73.0 0.0 2.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS31880.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B PRELI PF04707.14 CDS31881.1 - 3.5e-09 36.7 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Sec1 PF00995.23 CDS31882.1 - 1.7e-66 225.7 0.0 4.9e-66 224.2 0.0 1.7 1 1 0 1 1 1 1 Sec1 family HAD_2 PF13419.6 CDS31883.1 - 1.7e-22 80.3 0.0 2e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDS31883.1 - 7.8e-13 49.2 0.0 7.2e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDS31883.1 - 0.00083 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CDS31883.1 - 0.0009 19.7 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDS31883.1 - 0.0037 17.3 0.0 1.6 8.9 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF4710 PF15828.5 CDS31883.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) eIF-5_eIF-2B PF01873.17 CDS31884.1 - 1.6e-38 131.2 0.4 3.1e-38 130.2 0.4 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CDS31884.1 - 6.8e-19 67.8 0.4 2.7e-18 65.9 0.1 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon zf-ribbon_3 PF13248.6 CDS31884.1 - 0.47 9.9 2.0 11 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CpG_bind_C PF12269.8 CDS31885.1 - 5.4e-80 268.5 1.6 5.4e-80 268.5 1.6 1.5 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain TRPM_tetra PF16519.5 CDS31885.1 - 0.059 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM LEM PF03020.15 CDS31887.1 - 1.1e-13 50.5 0.1 2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 LEM domain MSC PF09402.10 CDS31887.1 - 4.9e-12 46.0 0.1 8.6e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Ish1 PF10281.9 CDS31887.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein SUR7 PF06687.12 CDS31887.1 - 0.13 11.9 0.6 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 SUR7/PalI family SNF2_N PF00176.23 CDS31888.1 - 4e-73 246.1 0.6 7.4e-73 245.3 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cation_efflux PF01545.21 CDS31888.1 - 6e-48 163.2 4.0 9.7e-48 162.5 4.0 1.4 1 0 0 1 1 1 1 Cation efflux family SLIDE PF09111.10 CDS31888.1 - 9.8e-38 128.7 0.2 9.8e-38 128.7 0.2 3.2 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 CDS31888.1 - 6e-29 101.0 2.4 6e-29 101.0 2.4 3.3 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 CDS31888.1 - 2.1e-19 69.9 0.1 4.5e-18 65.6 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS31888.1 - 1.9e-12 47.5 0.0 7e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDS31888.1 - 5.9e-07 29.4 0.0 1.7e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 CDS31888.1 - 3.5e-06 27.1 0.6 0.0047 17.1 0.0 3.1 3 0 0 3 3 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 CDS31888.1 - 9.3e-05 21.7 0.1 0.00037 19.8 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CDS31888.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ZT_dimer PF16916.5 CDS31888.1 - 0.026 14.6 0.3 0.099 12.8 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Tsg PF04668.12 CDS31888.1 - 0.029 15.0 0.2 4.4 8.0 0.0 3.0 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region DUF4800 PF16057.5 CDS31888.1 - 0.058 12.6 0.3 0.15 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) TetR_C_7 PF14246.6 CDS31888.1 - 0.1 12.6 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain DUF5399 PF17377.2 CDS31888.1 - 0.17 11.7 0.6 0.65 9.8 0.6 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5399) AAA PF00004.29 CDS31889.1 - 3.6e-42 143.9 0.0 7.5e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS31889.1 - 6.5e-12 45.1 0.0 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDS31889.1 - 1.3e-06 28.9 0.1 2.6e-05 24.7 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 CDS31889.1 - 1.9e-06 28.1 0.0 4.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDS31889.1 - 2.7e-06 27.4 0.0 8.9e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CDS31889.1 - 3.8e-05 23.5 0.2 9e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 CDS31889.1 - 7e-05 23.1 1.2 0.0095 16.2 0.3 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDS31889.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDS31889.1 - 0.0019 18.4 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDS31889.1 - 0.0024 17.7 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CDS31889.1 - 0.0024 17.1 0.0 0.0058 15.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CDS31889.1 - 0.0025 18.3 0.0 0.014 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CDS31889.1 - 0.0072 15.8 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ATPase PF06745.13 CDS31889.1 - 0.0092 15.3 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 CDS31889.1 - 0.011 15.2 0.1 0.029 13.7 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RILP PF11461.8 CDS31889.1 - 0.012 15.9 1.7 0.027 14.7 1.7 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_3 PF07726.11 CDS31889.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDS31889.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDS31889.1 - 0.02 14.6 0.1 0.12 12.1 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 CDS31889.1 - 0.027 14.2 0.0 0.076 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS31889.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MscS_porin PF12795.7 CDS31889.1 - 0.032 13.8 2.9 0.054 13.0 2.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TsaE PF02367.17 CDS31889.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CDS31889.1 - 0.039 14.0 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CDS31889.1 - 0.044 13.6 0.6 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CDS31889.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CDS31889.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CDS31889.1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CDS31889.1 - 0.074 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDS31889.1 - 0.086 13.2 0.6 0.46 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDS31889.1 - 0.11 11.8 1.1 2 7.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APG6_N PF17675.1 CDS31889.1 - 0.12 13.0 1.8 0.23 12.0 1.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_30 PF13604.6 CDS31889.1 - 0.13 12.0 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Spore_YhcN_YlaJ PF09580.10 CDS31889.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Prominin PF05478.11 CDS31889.1 - 0.16 9.9 0.2 0.26 9.2 0.2 1.3 1 0 0 1 1 1 0 Prominin HR1 PF02185.16 CDS31889.1 - 0.64 10.2 5.7 9.6 6.4 4.2 2.6 1 1 1 2 2 2 0 Hr1 repeat CAF1 PF04857.20 CDS31890.1 - 1.8e-22 79.9 1.2 4.5e-13 49.1 0.0 2.7 2 1 0 2 2 2 2 CAF1 family ribonuclease zf-C2H2_4 PF13894.6 CDS31891.1 - 1.2e-11 44.4 54.9 0.017 15.9 0.8 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS31891.1 - 3e-11 43.1 56.5 0.0016 18.8 1.0 8.1 6 1 2 8 8 8 5 Zinc finger, C2H2 type zf-Di19 PF05605.12 CDS31891.1 - 0.0019 18.4 42.5 0.69 10.3 0.5 5.9 2 2 4 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CDS31891.1 - 0.0084 16.5 6.1 0.057 13.9 0.7 9.0 9 0 0 9 9 9 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDS31891.1 - 0.01 15.6 1.8 0.01 15.6 1.8 5.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.7 CDS31891.1 - 0.024 15.0 2.6 0.024 15.0 2.6 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type HNH_5 PF14279.6 CDS31891.1 - 0.088 12.7 0.5 0.088 12.7 0.5 4.8 4 1 0 4 4 4 0 HNH endonuclease zf-C2H2_2 PF12756.7 CDS31891.1 - 0.29 11.5 40.1 1.5 9.2 6.8 6.6 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 CDS31891.1 - 5.2 7.4 34.5 0.24 11.7 2.0 5.6 3 2 2 5 5 5 0 TFIIH C1-like domain zf-C3HC4_2 PF13923.6 CDS31892.1 - 4e-14 52.2 9.8 6.6e-14 51.5 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS31892.1 - 3.9e-10 39.4 10.0 6.4e-10 38.7 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 CDS31892.1 - 3.1e-08 34.2 0.0 6.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 CDS31892.1 - 5.3e-08 33.1 8.6 8.5e-08 32.4 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS31892.1 - 5.7e-07 29.3 7.8 8.2e-07 28.8 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS31892.1 - 9.8e-06 25.5 8.3 1.9e-05 24.6 8.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDS31892.1 - 4.6e-05 23.3 7.5 8e-05 22.5 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 CDS31892.1 - 0.00013 21.7 5.0 0.00024 20.9 5.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CDS31892.1 - 0.00015 21.5 5.9 0.0003 20.5 5.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CDS31892.1 - 0.00083 19.2 4.0 0.0015 18.4 4.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDS31892.1 - 0.00086 19.4 7.9 0.0015 18.7 7.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDS31892.1 - 0.0051 17.1 7.9 0.023 15.0 7.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 CDS31892.1 - 0.018 15.1 2.8 0.052 13.7 2.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 CDS31892.1 - 0.056 13.3 8.8 1.5 8.7 9.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C4_Topoisom PF01396.19 CDS31892.1 - 0.081 12.7 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_17 PF17120.5 CDS31892.1 - 0.16 11.6 3.6 0.24 11.0 3.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_5 PF17121.5 CDS31892.1 - 0.22 11.4 8.0 0.69 9.9 8.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CDS31892.1 - 0.29 10.9 6.6 0.53 10.1 6.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 CDS31892.1 - 0.43 10.7 3.0 0.94 9.6 3.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDS31892.1 - 4.4 7.2 6.0 11 5.9 6.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 CDS31892.1 - 4.5 7.4 6.2 8.4 6.5 6.2 1.5 1 0 0 1 1 1 0 Zinc-finger Phosphodiest PF01663.22 CDS31893.1 - 4.3e-12 46.3 2.3 1.8e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDS31893.1 - 0.2 11.0 0.0 0.59 9.5 0.0 1.6 1 1 1 2 2 2 0 Sulfatase Ets PF00178.22 CDS31896.1 - 1.3e-35 121.7 0.2 2.5e-35 120.8 0.2 1.5 1 0 0 1 1 1 1 Ets-domain SelP_N PF04592.14 CDS31896.1 - 0.44 9.9 10.3 0.69 9.3 10.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 CDS31896.1 - 0.69 9.1 1.5 0.89 8.7 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDKN3 PF05706.12 CDS31897.1 - 0.022 14.4 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) tRNA_bind PF01588.20 CDS31897.1 - 0.046 13.8 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative tRNA binding domain CoaE PF01121.20 CDS31898.1 - 1e-10 41.5 0.1 1.2e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase CTP_transf_like PF01467.26 CDS31898.1 - 8.4e-07 29.3 0.0 2.4e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Cytidylyltransferase-like AAA_18 PF13238.6 CDS31898.1 - 0.0039 17.7 0.1 0.0097 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain Transposase_1 PF01359.18 CDS31899.1 - 3.3e-10 39.7 0.0 8.5e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) Cadherin PF00028.17 CDS31900.1 - 1.8e-84 278.3 0.2 1.6e-15 57.3 0.0 6.8 7 0 0 7 7 7 6 Cadherin domain Cadherin_pro PF08758.11 CDS31900.1 - 5.9e-06 26.4 0.1 0.0058 16.8 0.0 3.4 3 1 0 3 3 3 2 Cadherin prodomain like Pepdidase_M14_N PF18027.1 CDS31900.1 - 0.18 12.1 0.1 0.66 10.3 0.1 2.0 1 1 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain Ig_3 PF13927.6 CDS31901.2 - 6.1e-72 238.2 37.4 1.2e-09 38.6 0.1 30.1 33 0 0 33 33 31 10 Immunoglobulin domain Ig_2 PF13895.6 CDS31901.2 - 5.2e-39 132.5 11.5 0.0012 19.1 0.1 19.7 21 0 0 21 21 19 7 Immunoglobulin domain ig PF00047.25 CDS31901.2 - 4.4e-37 126.1 32.2 0.001 19.2 0.0 25.5 28 1 0 28 28 27 6 Immunoglobulin domain I-set PF07679.16 CDS31901.2 - 4.4e-35 119.6 12.6 1.7e-05 24.8 0.0 16.9 19 1 0 19 19 18 7 Immunoglobulin I-set domain EMP24_GP25L PF01105.24 CDS31901.2 - 3.3e-24 85.8 0.1 7.6e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Laminin_B PF00052.18 CDS31901.2 - 2.2e-21 76.2 0.0 2.4e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 Laminin B (Domain IV) V-set PF07686.17 CDS31901.2 - 8.2e-19 67.8 26.3 1.3 9.3 0.0 21.3 25 3 0 25 25 24 4 Immunoglobulin V-set domain Ldl_recept_a PF00057.18 CDS31901.2 - 2.9e-15 56.2 31.6 1.2e-07 31.8 6.9 4.0 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A Malic_M PF03949.15 CDS31901.2 - 3.1e-06 26.7 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Ig_6 PF18452.1 CDS31901.2 - 1.4e-05 24.6 0.4 0.1 12.1 0.0 5.4 6 0 0 6 6 6 1 Immunoglobulin domain BPL_C PF02237.17 CDS31901.2 - 0.00073 19.4 4.0 0.44 10.5 0.0 5.4 5 0 0 5 5 5 1 Biotin protein ligase C terminal domain SdrD_B PF17210.3 CDS31901.2 - 0.0051 17.0 0.2 0.016 15.4 0.2 1.8 1 0 0 1 1 1 1 SdrD B-like domain V-set_CD47 PF08204.11 CDS31901.2 - 0.039 13.9 4.5 58 3.7 0.0 6.7 8 0 0 8 8 7 0 CD47 immunoglobulin-like domain C2-set_2 PF08205.12 CDS31901.2 - 0.18 11.9 5.9 2.2 8.4 0.0 5.5 5 0 0 5 5 4 0 CD80-like C2-set immunoglobulin domain Ribosomal_S16 PF00886.19 CDS31902.1 - 1.8e-17 63.1 0.0 3.4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 GCP_C_terminal PF04130.13 CDS31903.1 - 2.4e-71 240.7 6.1 2.4e-71 240.7 6.1 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDS31903.1 - 4.2e-56 190.8 0.5 8.6e-56 189.8 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal dsrm PF00035.26 CDS31903.1 - 9.2e-10 39.1 0.2 6.5e-08 33.2 0.0 3.1 3 0 0 3 3 3 1 Double-stranded RNA binding motif Staufen_C PF16482.5 CDS31903.1 - 0.03 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Staufen C-terminal domain Ras PF00071.22 CDS31904.1 - 5.6e-09 35.8 0.1 1.7e-07 31.0 0.0 2.6 2 1 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 CDS31904.1 - 3.2e-06 26.8 0.0 2.3e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS31904.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CDS31904.1 - 0.015 14.7 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 CDS31904.1 - 0.043 14.0 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDS31904.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit E3_UFM1_ligase PF09743.9 CDS31905.1 - 2.1e-87 293.2 3.7 1.2e-86 290.7 2.0 2.2 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 DUF742 PF05331.11 CDS31905.1 - 0.18 11.6 1.1 6.2 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF742) Cpn60_TCP1 PF00118.24 CDS31906.1 - 6.2e-159 529.8 1.5 7e-159 529.6 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HTH_51 PF18558.1 CDS31906.1 - 0.16 11.9 0.2 17 5.3 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Dynein_light PF01221.18 CDS31907.1 - 6.2e-15 55.3 0.2 1.3e-14 54.2 0.2 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_7 PF13499.6 CDS31907.1 - 0.0015 19.0 0.8 0.0031 17.9 0.4 1.6 2 0 0 2 2 2 1 EF-hand domain pair DUF347 PF03988.12 CDS31907.1 - 0.028 14.6 0.4 0.042 14.0 0.4 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF1160 PF06648.11 CDS31907.1 - 0.033 14.2 0.1 0.84 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) EF-hand_6 PF13405.6 CDS31907.1 - 0.083 12.9 0.1 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 CDS31908.1 - 4.3e-10 39.9 0.3 7.9e-10 39.1 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS31908.1 - 7e-08 31.8 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS31908.1 - 1e-06 27.8 0.2 0.002 17.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDS31908.1 - 0.0012 18.6 0.7 0.018 14.9 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS31908.1 - 0.006 16.0 0.0 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 EF hand Dynein_light PF01221.18 CDS31908.1 - 0.0075 16.6 5.5 0.016 15.5 0.4 2.7 3 0 0 3 3 3 1 Dynein light chain type 1 HGD-D PF06050.13 CDS31908.1 - 0.049 13.4 0.2 0.061 13.1 0.2 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component LD_cluster2 PF18163.1 CDS31908.1 - 0.069 12.7 0.3 0.57 9.7 0.1 2.0 1 1 1 2 2 2 0 SLOG cluster2 EF-hand_9 PF14658.6 CDS31908.1 - 0.092 13.1 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain DUF2795 PF11387.8 CDS31908.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) SPARC_Ca_bdg PF10591.9 CDS31908.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BTG PF07742.12 CDS31908.1 - 0.14 12.0 1.1 0.26 11.1 0.5 1.7 2 0 0 2 2 2 0 BTG family Dynein_light PF01221.18 CDS31909.1 - 2.7e-15 56.4 0.2 6.1e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 Dynein light chain type 1 EF-hand_6 PF13405.6 CDS31909.1 - 6.5e-08 31.9 0.1 0.0096 15.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS31909.1 - 9e-08 31.2 0.5 0.0093 15.5 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS31909.1 - 3.4e-07 30.6 0.4 3.4e-07 30.6 0.4 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDS31909.1 - 5.4e-05 22.5 4.2 0.095 12.2 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS31909.1 - 0.00091 19.0 0.3 0.0033 17.2 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain pair Sigma70_r1_1 PF03979.14 CDS31909.1 - 2.3 8.3 6.8 8.6 6.5 0.0 3.1 3 1 0 3 3 3 0 Sigma-70 factor, region 1.1 CNPase PF05881.12 CDS31910.1 - 3.6e-24 85.6 0.1 2.8e-23 82.7 0.0 2.2 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Vps39_1 PF10366.9 CDS31910.1 - 2.4e-21 76.0 0.5 1e-19 70.8 0.1 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CDS31910.1 - 4.8e-19 68.8 0.0 1.7e-18 67.1 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CDS31910.1 - 1.3e-08 34.8 0.5 0.0036 17.0 0.0 3.1 2 1 1 3 3 3 2 CNH domain AAA_33 PF13671.6 CDS31910.1 - 3.6e-06 27.2 0.0 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Yippee-Mis18 PF03226.14 CDS31910.1 - 0.014 15.6 0.1 1.4 9.2 0.0 3.3 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_16 PF13191.6 CDS31910.1 - 0.02 15.3 0.0 0.066 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Plectin PF00681.20 CDS31910.1 - 0.025 14.4 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat AAA_5 PF07728.14 CDS31910.1 - 0.03 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.17 CDS31910.1 - 0.046 12.6 0.1 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 Papillomavirus helicase AAA_18 PF13238.6 CDS31910.1 - 0.074 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS31910.1 - 0.13 12.6 0.0 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDS31910.1 - 0.13 12.6 0.0 0.47 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L37 PF08561.10 CDS31911.1 - 6e-06 26.8 0.1 8.6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 DHHC PF01529.20 CDS31912.1 - 6.8e-38 129.8 16.6 6.8e-38 129.8 16.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 CDS31912.1 - 1.6 8.9 5.7 3.4 7.9 5.7 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger ArfGap PF01412.18 CDS31913.1 - 1.9e-22 79.5 1.6 3.3e-22 78.7 1.6 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 CDS31913.1 - 0.022 14.2 1.4 0.048 13.2 1.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.7 CDS31913.1 - 0.12 12.4 2.5 0.21 11.6 1.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon Hint PF01079.20 CDS31914.1 - 5.3e-37 127.4 0.0 7.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Hint module HH_signal PF01085.18 CDS31914.1 - 1.4e-17 63.8 0.0 5.7e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Hedgehog amino-terminal signalling domain Ribosomal_60s PF00428.19 CDS31915.2 - 2.3e-18 66.6 19.6 1.5e-17 64.0 19.6 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 CDS31915.2 - 0.0091 16.1 6.4 0.012 15.7 6.4 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF5525 PF17663.1 CDS31915.2 - 0.38 8.8 5.4 0.44 8.6 5.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) E1-E2_ATPase PF00122.20 CDS31916.1 - 1.8e-45 154.7 1.2 1.8e-45 154.7 1.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CDS31916.1 - 1.5e-36 126.6 0.0 3.6e-28 99.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDS31916.1 - 1.1e-35 121.8 4.8 3.3e-14 53.0 0.1 3.9 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CDS31916.1 - 0.0004 20.2 4.4 0.012 15.3 1.1 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase GFRP PF06399.13 CDS31916.1 - 0.07 13.0 0.0 0.75 9.7 0.0 2.7 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Hydrolase_6 PF13344.6 CDS31916.1 - 0.16 12.1 0.1 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDS31916.1 - 0.18 11.8 0.2 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 CDS31916.1 - 0.31 11.1 0.9 1.4 9.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function Ras PF00071.22 CDS31917.1 - 1.3e-40 138.6 0.1 2.7e-40 137.6 0.1 1.6 1 0 0 1 1 1 1 Ras family Hira PF07569.11 CDS31917.1 - 2.6e-36 125.5 0.0 1.5e-35 123.0 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 CDS31917.1 - 6.4e-24 83.8 26.9 2.4e-06 28.2 0.2 9.0 8 1 0 8 8 8 5 WD domain, G-beta repeat Roc PF08477.13 CDS31917.1 - 5e-18 65.5 0.0 1.5e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ANAPC4_WD40 PF12894.7 CDS31917.1 - 1.9e-13 50.5 0.2 0.073 13.4 0.0 6.6 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CDS31917.1 - 6.7e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif Arf PF00025.21 CDS31917.1 - 8.6e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family PD40 PF07676.12 CDS31917.1 - 1.9e-05 24.5 5.0 0.14 12.1 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CDS31917.1 - 0.00012 21.1 0.3 0.065 12.2 0.1 4.0 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS31917.1 - 0.00014 21.8 0.0 0.8 9.6 0.0 4.1 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A VirB7 PF17413.2 CDS31917.1 - 0.24 10.8 1.7 0.6 9.5 0.0 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein virB7 Hormone_3 PF00159.18 CDS31918.1 - 4.1e-05 23.5 0.3 6.6e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide Hormone_3 PF00159.18 CDS31919.1 - 1.2e-05 25.3 0.1 1.8e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Pancreatic hormone peptide DUF647 PF04884.14 CDS31920.1 - 1.5e-92 309.7 1.2 2.1e-92 309.1 1.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4952 PF16310.5 CDS31920.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) Serpin PF00079.20 CDS31921.1 - 5.1e-84 282.7 1.1 6.6e-84 282.4 1.1 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) LMP PF04778.12 CDS31921.1 - 0.054 13.4 1.1 0.12 12.3 0.6 1.8 1 1 1 2 2 2 0 LMP repeated region DUF953 PF06110.11 CDS31923.1 - 5.3e-34 116.4 0.1 5.9e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 CDS31923.1 - 0.00022 21.2 0.2 0.00049 20.0 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDS31923.1 - 0.0074 16.0 0.2 0.014 15.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDS31923.1 - 0.023 15.0 0.0 0.095 13.0 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like zinc_ribbon_9 PF14369.6 CDS31923.1 - 0.065 13.5 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon DEAD PF00270.29 CDS31924.1 - 8.5e-41 139.6 0.2 1.5e-40 138.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS31924.1 - 4e-32 110.9 0.3 1e-30 106.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CDS31924.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDS31924.1 - 5.2e-05 23.3 0.2 0.00022 21.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDS31924.1 - 8e-05 23.0 1.5 0.0026 18.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 CDS31924.1 - 0.00074 18.4 0.4 0.52 9.0 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 CDS31924.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 CDS31924.1 - 0.0095 16.2 0.2 0.049 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDS31924.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 CDS31924.1 - 0.057 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PhoH PF02562.16 CDS31924.1 - 0.18 11.2 1.9 0.76 9.2 1.9 2.0 1 1 0 1 1 1 0 PhoH-like protein Dynein_light PF01221.18 CDS31926.1 - 4.1e-15 55.9 0.6 1.1e-14 54.4 0.1 2.0 2 1 0 2 2 2 1 Dynein light chain type 1 EF-hand_7 PF13499.6 CDS31926.1 - 3.7e-08 33.7 0.6 3.7e-08 33.7 0.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS31926.1 - 1.7e-05 24.4 0.5 0.08 12.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDS31926.1 - 7.4e-05 22.0 0.1 0.075 12.6 0.0 2.7 2 0 0 2 2 2 2 EF hand Tai4 PF16695.5 CDS31926.1 - 0.093 13.3 0.9 0.18 12.3 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein EF-hand_9 PF14658.6 CDS31926.1 - 0.11 12.9 0.5 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Ribosomal_S11 PF00411.19 CDS31927.1 - 4e-42 143.1 1.3 5.1e-42 142.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Sec1 PF00995.23 CDS31928.1 - 6.8e-87 293.0 0.2 7.9e-87 292.8 0.2 1.0 1 0 0 1 1 1 1 Sec1 family Syja_N PF02383.18 CDS31929.1 - 7.6e-62 209.5 0.1 1.1e-61 208.9 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CDS31929.1 - 1.5e-12 47.5 0.1 4.2e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF1866 PF08952.11 CDS31929.1 - 2e-10 40.7 0.1 5.5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Mic1 PF07035.12 CDS31929.1 - 0.048 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Pro_isomerase PF00160.21 CDS31930.1 - 2.2e-45 154.8 0.0 4.4e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AP3D1 PF06375.11 CDS31930.1 - 0.0011 19.3 9.7 0.0011 19.3 9.7 5.5 4 2 2 6 6 6 1 AP-3 complex subunit delta-1 Pkinase PF00069.25 CDS31931.1 - 3.9e-65 219.8 0.3 9.3e-64 215.3 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31931.1 - 1.1e-51 175.6 0.0 2.8e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PKK PF12474.8 CDS31931.1 - 1.1e-13 51.5 22.1 1.1e-13 51.5 22.1 4.8 2 2 1 3 3 3 1 Polo kinase kinase zf-LYAR PF08790.11 CDS31931.1 - 2.6e-12 46.4 6.4 2.6e-12 46.4 6.4 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger NPM1-C PF16276.5 CDS31931.1 - 0.014 15.4 0.4 0.048 13.6 0.4 1.9 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain APH PF01636.23 CDS31931.1 - 0.97 9.3 0.0 0.97 9.3 0.0 3.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family ZnuA PF01297.17 CDS31931.1 - 1.1 8.6 8.1 1.2 8.5 1.2 3.4 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic Ribosomal_S17e PF00833.18 CDS31932.1 - 4.1e-51 172.0 0.2 4.8e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 14-3-3 PF00244.20 CDS31933.1 - 3.5e-100 334.1 5.7 4e-100 333.9 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein tRNA_Me_trans PF03054.16 CDS31934.1 - 3.7e-93 312.1 0.0 4.2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase DUF973 PF06157.11 CDS31935.1 - 0.012 14.6 0.2 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3188 PF11384.8 CDS31935.1 - 0.056 13.2 3.1 5.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF1772 PF08592.11 CDS31935.1 - 0.13 12.6 0.6 0.29 11.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3040 PF11239.8 CDS31935.1 - 0.22 11.8 0.5 0.3 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Tim44 PF04280.15 CDS31936.1 - 3e-36 124.7 1.9 3.9e-35 121.1 0.0 2.9 3 0 0 3 3 3 1 Tim44-like domain PPDK_N PF01326.19 CDS31936.1 - 0.00045 19.6 1.2 0.0006 19.2 1.2 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain tRNA-synt_1d PF00750.19 CDS31936.1 - 0.033 13.1 1.9 0.067 12.1 1.9 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (R) Com_YlbF PF06133.11 CDS31936.1 - 1 10.0 17.1 1.7 9.3 10.5 2.9 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Prominin PF05478.11 CDS31936.1 - 1.2 7.0 4.8 0.78 7.6 2.8 1.5 2 0 0 2 2 2 0 Prominin DUF3347 PF11827.8 CDS31936.1 - 2.5 8.3 14.6 6.3 7.0 11.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) Arm-DNA-bind_2 PF12167.8 CDS31936.1 - 3.2 7.7 5.0 2 8.4 0.3 3.0 3 1 1 4 4 4 0 Arm DNA-binding domain DUF4407 PF14362.6 CDS31936.1 - 3.3 7.0 6.9 4.7 6.5 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prenyltrans PF00432.21 CDS31937.1 - 9.5e-25 86.0 0.6 1.7e-10 40.4 0.0 4.8 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Oxidored-like PF09791.9 CDS31937.1 - 3.7e-10 39.3 1.4 7.4e-10 38.3 1.4 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Cation_ATPase_C PF00689.21 CDS31938.1 - 8.9e-42 142.8 7.2 1.4e-41 142.2 7.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.8 CDS31938.1 - 7.1e-12 45.6 0.8 1.9e-11 44.2 0.8 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 CDS31938.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDS31938.1 - 0.00024 21.5 0.1 0.0011 19.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ost5 PF05251.12 CDS31938.1 - 0.68 10.2 3.1 1.1 9.5 1.2 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 PDZ PF00595.24 CDS31940.2 - 6.2e-15 55.3 1.1 0.00033 20.9 0.0 5.2 4 1 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CDS31940.2 - 5e-10 39.1 0.3 0.22 11.4 0.0 4.7 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CDS31940.2 - 9.8e-10 38.6 2.3 0.0094 16.3 0.2 4.6 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 CDS31941.1 - 1.6e-39 134.1 0.1 8.8e-10 38.8 0.1 4.6 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CDS31941.1 - 6e-26 90.1 3.7 6.5e-08 32.3 0.0 4.7 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CDS31941.1 - 1.8e-14 53.8 0.0 0.001 19.3 0.1 4.5 4 0 0 4 4 4 4 PDZ domain SYS1 PF09801.9 CDS31942.1 - 4.1e-43 147.0 8.5 4.6e-43 146.8 8.5 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COQ9 PF08511.11 CDS31943.1 - 3.7e-30 103.5 1.7 6.3e-30 102.8 0.2 2.0 2 0 0 2 2 2 1 COQ9 IML1 PF12257.8 CDS31944.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 zf-MYND PF01753.18 CDS31945.1 - 5.4e-09 36.0 20.2 1.6e-08 34.4 20.2 1.9 1 0 0 1 1 1 1 MYND finger DUF1413 PF07205.11 CDS31945.1 - 0.092 12.8 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) EF-hand_1 PF00036.32 CDS31946.1 - 1.3e-24 83.9 15.7 5.4e-07 28.7 0.1 5.9 5 1 1 6 6 6 5 EF hand EF-hand_7 PF13499.6 CDS31946.1 - 8.4e-20 71.0 11.5 1.3e-07 31.9 0.1 3.7 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDS31946.1 - 3.5e-18 63.9 14.5 7e-06 25.6 0.0 5.7 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 CDS31946.1 - 1.8e-17 61.9 16.7 0.0013 18.1 0.5 5.6 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 CDS31946.1 - 2.7e-11 43.1 11.6 0.0055 16.5 0.4 5.4 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_4 PF12763.7 CDS31946.1 - 2.9e-05 24.0 8.0 0.015 15.2 0.1 3.6 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CDS31946.1 - 0.0022 18.2 1.0 2.5 8.4 0.0 3.8 3 2 1 4 4 4 1 Dockerin type I domain Caleosin PF05042.13 CDS31946.1 - 0.0035 17.3 2.6 5.4 6.9 0.1 4.5 4 1 1 5 5 5 1 Caleosin related protein EF-hand_9 PF14658.6 CDS31946.1 - 0.031 14.6 0.1 5.3 7.4 0.0 3.4 3 1 2 5 5 5 0 EF-hand domain SHOCT PF09851.9 CDS31946.1 - 0.082 12.7 3.8 2.4 8.0 0.3 3.1 3 0 0 3 3 3 0 Short C-terminal domain SPARC_Ca_bdg PF10591.9 CDS31946.1 - 0.086 13.2 7.4 55 4.1 1.7 4.5 2 1 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Armet PF10208.9 CDS31946.1 - 0.11 12.5 0.8 1.6 8.6 0.1 2.3 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding EF-hand_10 PF14788.6 CDS31946.1 - 0.21 11.5 9.4 3.3 7.7 0.1 4.2 4 0 0 4 4 4 0 EF hand zf-3CxxC PF13695.6 CDS31947.1 - 2.5e-17 63.2 0.5 2.5e-17 63.2 0.5 2.3 2 1 0 2 2 2 1 Zinc-binding domain zf-3CxxC PF13695.6 CDS31948.1 - 2.5e-10 40.7 0.6 2.5e-10 40.7 0.6 1.6 2 0 0 2 2 2 1 Zinc-binding domain TFIIS_C PF01096.18 CDS31948.1 - 0.12 12.2 0.5 0.12 12.2 0.5 3.1 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) zf-LYAR PF08790.11 CDS31948.1 - 0.37 10.7 5.2 0.98 9.4 0.3 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-3CxxC_2 PF17180.4 CDS31948.1 - 1.1 10.0 8.7 0.48 11.2 0.6 2.7 2 1 0 3 3 3 0 Zinc-binding domain Pcc1 PF09341.10 CDS31949.1 - 8.7e-23 80.3 0.1 1.4e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 CS PF04969.16 CDS31949.1 - 3e-16 60.2 0.0 1.1e-15 58.4 0.0 2.0 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 CDS31949.1 - 8.8e-11 41.6 0.1 2.4e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. Atrophin-1 PF03154.15 CDS31949.1 - 0.11 10.8 5.8 0.14 10.4 5.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family STb_secrete PF09075.10 CDS31949.1 - 0.14 12.3 0.2 0.42 10.7 0.2 1.8 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory DUF3987 PF13148.6 CDS31949.1 - 2.5 7.0 5.1 4.5 6.2 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TFIID_30kDa PF03540.13 CDS31950.1 - 2.1e-17 62.8 0.0 3.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit GAT PF03127.14 CDS31950.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 GAT domain NUDIX PF00293.28 CDS31951.1 - 8.8e-14 51.7 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.21 CDS31952.1 - 1.7e-31 109.8 0.1 2e-30 106.4 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 CDS31952.1 - 3e-23 81.7 0.0 5.7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 CDS31952.1 - 8.6e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Peptidase_C14 PF00656.22 CDS31953.1 - 7.9e-43 147.2 0.2 1.1e-42 146.7 0.2 1.2 1 0 0 1 1 1 1 Caspase domain SRP68 PF16969.5 CDS31954.1 - 1.3e-142 476.7 6.4 1.5e-142 476.5 6.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 CDS31954.1 - 0.002 17.0 0.0 0.0048 15.8 0.0 1.6 1 0 0 1 1 1 1 BRO1-like domain DUF3960 PF13142.6 CDS31954.1 - 0.0068 16.5 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3960) TPR_2 PF07719.17 CDS31954.1 - 0.008 16.2 2.7 3.4 8.0 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS31954.1 - 0.024 14.8 3.3 0.36 11.1 0.9 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDS31954.1 - 0.16 12.6 1.8 6.3 7.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS31954.1 - 0.45 10.6 6.9 0.88 9.7 2.1 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ARID PF01388.21 CDS31955.1 - 1.9e-13 50.8 0.0 4.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 CDS31955.1 - 2e-09 37.9 0.1 5.6e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain zf_Hakai PF18408.1 CDS31955.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain PARG_cat PF05028.14 CDS31955.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Neur_chan_LBD PF02931.23 CDS31956.1 - 1.3e-48 165.3 3.7 1.9e-48 164.7 3.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS31956.1 - 8.3e-31 107.9 0.0 1.8e-30 106.8 0.0 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4283 PF14111.6 CDS31956.1 - 0.23 11.0 1.4 4 6.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) DSHCT PF08148.12 CDS31957.1 - 4.6e-31 107.7 0.0 1.3e-30 106.3 0.0 1.8 1 1 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDS31957.1 - 1.3e-17 64.1 0.0 2.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS31957.1 - 1.8e-07 31.3 0.0 3.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS31957.1 - 6.6e-07 29.7 0.0 4.4e-06 27.0 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDS31957.1 - 0.017 15.4 0.0 0.068 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 CDS31960.1 - 2.4e-18 65.7 3.8 9.8e-06 25.3 0.6 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 CDS31960.1 - 0.05 11.8 86.0 0.015 13.5 34.0 2.1 2 0 0 2 2 2 0 Nop14-like family DUF3721 PF12518.8 CDS31960.1 - 3.7 7.5 4.9 1.5 8.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function RRM_1 PF00076.22 CDS31961.1 - 3.5e-16 58.8 0.0 4.4e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_1 PF00170.21 CDS31962.1 - 3.9e-11 42.9 12.7 6.2e-11 42.2 12.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDS31962.1 - 8.6e-07 28.9 15.5 1.5e-06 28.1 15.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CDS31962.1 - 1.4e-06 28.7 11.8 2.3e-06 28.0 11.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 CDS31962.1 - 5.9e-05 22.8 0.9 7.7e-05 22.4 0.9 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 UPF0242 PF06785.11 CDS31962.1 - 0.0062 16.7 2.4 0.0062 16.7 2.4 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 CDS31962.1 - 0.011 15.5 1.6 0.027 14.3 1.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 CDS31962.1 - 0.017 15.5 4.4 0.017 15.5 4.4 1.5 2 0 0 2 2 1 0 Cell division protein ZapB Macoilin PF09726.9 CDS31962.1 - 0.099 11.2 4.5 0.12 10.9 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Prominin PF05478.11 CDS31962.1 - 0.17 9.8 0.3 0.24 9.3 0.3 1.1 1 0 0 1 1 1 0 Prominin SCP-1 PF05483.12 CDS31962.1 - 0.2 9.6 3.4 0.27 9.2 3.4 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) CENP-F_leu_zip PF10473.9 CDS31962.1 - 0.2 11.7 7.8 0.32 11.0 7.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GCN5L1 PF06320.13 CDS31962.1 - 0.24 11.6 2.8 0.41 10.8 2.8 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3450 PF11932.8 CDS31962.1 - 0.57 9.5 4.7 1.1 8.6 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tmem26 PF09772.9 CDS31963.1 - 4.8e-64 216.5 14.4 5.1e-44 150.8 9.7 2.9 2 1 0 2 2 2 2 Transmembrane protein 26 DUF2362 PF10154.9 CDS31964.1 - 4.5e-156 520.7 0.2 5.3e-156 520.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) bZIP_1 PF00170.21 CDS31965.1 - 4.1e-07 30.0 18.0 4.1e-07 30.0 18.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 CDS31965.1 - 0.00035 21.0 16.9 0.00035 21.0 16.9 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF2448 PF10476.9 CDS31965.1 - 0.003 17.5 2.4 0.006 16.5 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2448) bZIP_2 PF07716.15 CDS31965.1 - 0.022 14.8 19.7 0.059 13.5 19.7 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Phage_GP20 PF06810.11 CDS31965.1 - 1.1 9.1 9.0 0.09 12.6 3.8 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 CDC37_N PF03234.14 CDS31965.1 - 1.4 9.8 7.0 0.4 11.6 2.9 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding CNDH2_C PF16858.5 CDS31965.1 - 4.3 7.1 11.2 0.21 11.5 3.0 2.5 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Homeodomain PF00046.29 CDS31967.1 - 4.2e-22 77.8 6.2 1.2e-21 76.3 6.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS31967.1 - 0.006 16.5 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain GAIN_A PF18619.1 CDS31967.1 - 0.029 14.6 0.2 0.029 14.6 0.2 2.0 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Chromo PF00385.24 CDS31968.1 - 5.6e-17 61.4 7.2 1.1e-15 57.3 2.8 2.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDS31968.1 - 8.1e-11 41.9 1.2 2.2e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 Chromo shadow domain DNA_pol_B PF00136.21 CDS31969.2 - 1.3e-108 363.7 0.0 1.8e-108 363.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDS31969.2 - 4.2e-24 85.3 0.0 1.5e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CDS31969.2 - 1.1e-19 70.9 0.0 2.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 CDS31969.2 - 1.8e-18 66.3 4.1 3.8e-18 65.3 4.1 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CDS31969.2 - 0.00027 19.9 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral zf_UBZ PF18439.1 CDS31969.2 - 0.075 12.6 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 CDS31969.2 - 0.11 12.2 0.3 20 5.0 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF2717 PF10911.8 CDS31969.2 - 0.12 12.2 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Aminotran_1_2 PF00155.21 CDS31970.1 - 3.6e-29 102.1 0.0 4.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDS31970.1 - 0.006 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C2H2_11 PF16622.5 CDS31972.1 - 3.8e-06 26.5 0.3 8.3e-06 25.5 0.3 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CDS31972.1 - 0.02 15.3 5.6 1.3 9.6 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS31972.1 - 0.023 15.5 5.5 0.039 14.8 1.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS31972.1 - 0.025 15.0 2.6 0.025 15.0 2.6 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type SLC3A2_N PF16028.5 CDS31973.2 - 4.2e-17 61.5 0.1 7e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Antimicrobial_7 PF08102.11 CDS31973.2 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Pkinase PF00069.25 CDS31974.1 - 2.1e-59 201.0 0.0 2.5e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31974.1 - 3.3e-21 75.7 0.0 4.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS31974.1 - 4.1e-06 26.9 0.0 9.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS31974.1 - 0.00013 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS31974.1 - 0.00021 20.7 0.2 0.00039 19.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDS31974.1 - 0.00047 19.8 0.2 0.00079 19.1 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CDS31974.1 - 0.0031 16.6 0.1 0.005 15.9 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CDS31974.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CDS31975.1 - 1.1e-65 221.6 0.1 1.3e-65 221.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31975.1 - 2.2e-18 66.5 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS31975.1 - 2.3e-09 37.6 0.2 1.2e-05 25.4 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS31975.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS31975.1 - 0.0035 16.2 0.1 0.025 13.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CDS31975.1 - 0.076 12.6 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2459 PF09601.10 CDS31975.1 - 0.09 12.6 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) RNase_PH PF01138.21 CDS31976.1 - 2.5e-22 79.8 0.0 3.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ThrE PF06738.12 CDS31976.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Peptidase_C54 PF03416.19 CDS31977.1 - 1.9e-85 286.7 0.0 2.5e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 CDS31977.1 - 0.032 13.7 0.2 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Peptidase family C78 zf-C4 PF00105.18 CDS31978.1 - 2.2e-43 146.6 26.1 6.6e-27 93.8 9.2 3.6 3 0 0 3 3 3 3 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS31978.1 - 2.5e-08 33.7 5.5 4.6e-08 32.9 5.5 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.16 CDS31978.1 - 0.0017 18.6 1.1 0.0017 18.6 1.1 3.5 4 0 0 4 4 4 2 C1 domain zinc_ribbon_6 PF14599.6 CDS31978.1 - 0.088 12.8 5.5 3 7.9 0.2 3.0 2 1 0 2 2 2 0 Zinc-ribbon zf-RRPl_C4 PF17026.5 CDS31978.1 - 1.1 9.4 11.2 1.6 8.9 0.4 3.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type Laminin_EGF PF00053.24 CDS31979.1 - 1.1e-76 252.7 224.5 3.3e-11 43.1 12.3 12.6 11 2 2 13 13 12 11 Laminin EGF domain Laminin_N PF00055.17 CDS31979.1 - 3.6e-65 219.8 0.4 3.6e-65 219.8 0.4 2.8 3 0 0 3 3 1 1 Laminin N-terminal (Domain VI) ADIP PF11559.8 CDS31979.1 - 0.00033 20.8 2.6 0.00033 20.8 2.6 4.7 2 2 2 4 4 4 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 CDS31979.1 - 0.00068 19.7 36.2 0.85 9.7 1.3 6.4 1 1 6 7 7 7 5 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CDS31979.1 - 0.0029 16.4 38.2 0.03 13.0 21.6 3.2 1 1 1 3 3 3 2 AAA domain Fib_alpha PF08702.10 CDS31979.1 - 0.0034 17.6 12.4 0.0034 17.6 12.4 5.1 1 1 5 7 7 7 2 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CDS31979.1 - 0.051 13.8 27.6 0.8 10.0 2.1 5.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Sec3_C_2 PF15278.6 CDS31979.1 - 0.49 10.8 3.4 0.59 10.5 0.6 2.6 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Baculo_PEP_C PF04513.12 CDS31979.1 - 0.69 9.9 35.2 0.52 10.4 1.1 6.0 2 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMP_2 PF06791.13 CDS31979.1 - 1.5 8.5 13.1 0.44 10.2 0.8 2.7 3 0 0 3 3 3 0 Prophage tail length tape measure protein Trimer_CC PF08954.11 CDS31979.1 - 1.6 8.3 5.8 2.5 7.7 0.3 3.5 2 1 1 3 3 3 0 Trimerisation motif RasGAP_C PF03836.15 CDS31979.1 - 3.1 8.0 24.3 0.55 10.4 12.4 3.7 3 1 0 3 3 3 0 RasGAP C-terminus HisKA PF00512.25 CDS31979.1 - 7.1 6.8 9.0 35 4.5 0.1 4.6 4 1 1 5 5 5 0 His Kinase A (phospho-acceptor) domain Laminin_II PF06009.12 CDS31979.1 - 8 6.5 42.3 0.74 9.8 8.3 5.6 3 2 2 5 5 5 0 Laminin Domain II Ribosomal_L35Ae PF01247.18 CDS31980.1 - 1.2e-44 150.3 0.9 1.5e-44 150.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDS31980.1 - 0.011 16.0 0.2 1.3 9.3 0.0 2.3 2 1 0 2 2 2 0 RimM N-terminal domain DUF2080 PF09853.9 CDS31980.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) LSM PF01423.22 CDS31982.1 - 1.7e-18 66.1 0.3 2.2e-18 65.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain LPD13 PF18825.1 CDS31982.1 - 0.07 12.9 0.5 0.088 12.6 0.5 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 WH1 PF00568.23 CDS31983.1 - 3.3e-27 94.6 0.0 6.1e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 CDS31983.1 - 2.7e-06 26.8 0.7 4.3e-06 26.2 0.7 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain Transposase_1 PF01359.18 CDS31987.1 - 0.0027 17.5 0.6 0.037 13.9 0.1 2.5 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDS31988.1 - 5e-06 26.5 0.1 7.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF3439 PF11921.8 CDS31991.1 - 0.0086 16.0 7.2 0.019 15.0 7.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) PRIMA1 PF16101.5 CDS31991.1 - 0.02 14.9 3.3 0.052 13.6 3.3 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PqiA PF04403.13 CDS31991.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Paraquat-inducible protein A TMEM154 PF15102.6 CDS31991.1 - 0.057 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 CDS31991.1 - 0.086 13.0 5.6 0.16 12.2 5.6 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Prominin PF05478.11 CDS31991.1 - 0.41 8.6 0.8 0.56 8.1 0.8 1.1 1 0 0 1 1 1 0 Prominin HTH_20 PF12840.7 CDS31992.1 - 0.00013 22.0 0.2 0.00024 21.1 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 CDS31992.1 - 0.00022 20.7 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 CDS31992.1 - 0.00058 19.7 0.4 0.00094 19.0 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 CDS31992.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_10 PF04967.12 CDS31992.1 - 0.0016 18.2 0.0 0.0051 16.6 0.1 1.7 2 0 0 2 2 2 1 HTH DNA binding domain Dcc1 PF09724.9 CDS31992.1 - 0.0068 15.8 0.2 0.0084 15.4 0.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 TFIIE_alpha PF02002.17 CDS31992.1 - 0.024 14.5 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit ANT PF03374.14 CDS31992.1 - 0.027 14.8 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain MarR PF01047.22 CDS31992.1 - 0.061 13.3 0.2 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 MarR family HTH_34 PF13601.6 CDS31992.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 CDS31992.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase DUF4250 PF14056.6 CDS31992.1 - 0.29 11.1 0.6 0.47 10.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) zf-C3HC4_3 PF13920.6 CDS31993.1 - 2.8e-07 30.3 8.9 6.5e-07 29.1 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS31993.1 - 1.3e-05 25.0 13.6 3.2e-05 23.7 13.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS31993.1 - 2.6e-05 24.1 12.2 0.00013 21.8 12.2 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDS31993.1 - 6.3e-05 22.7 12.0 0.00014 21.6 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS31993.1 - 0.00012 21.9 6.9 0.00027 20.7 6.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TACC_C PF05010.14 CDS31993.1 - 0.0017 18.2 3.3 0.0017 18.2 3.3 6.7 5 3 1 6 6 6 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_UBOX PF13445.6 CDS31993.1 - 0.0033 17.4 9.1 0.0096 15.9 9.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDS31993.1 - 0.0054 17.0 7.4 0.0054 17.0 7.4 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDS31993.1 - 0.014 15.7 10.5 0.014 15.7 10.5 2.1 2 0 0 2 2 1 0 Ring finger domain zf-ANAPC11 PF12861.7 CDS31993.1 - 0.021 14.8 2.2 0.047 13.7 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AAA_lid_5 PF17865.1 CDS31993.1 - 0.22 11.6 3.8 0.97 9.5 0.1 3.3 3 0 0 3 3 3 0 Midasin AAA lid domain NeA_P2 PF12312.8 CDS31993.1 - 0.41 10.0 3.2 1 8.7 3.2 1.6 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein zf-C3HC4_4 PF15227.6 CDS31993.1 - 0.64 10.2 11.7 0.22 11.7 8.4 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CDS31993.1 - 2 8.2 11.7 33 4.4 11.5 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_15 PF17032.5 CDS31993.1 - 5.5 7.8 10.4 2.6 8.8 6.6 2.6 2 0 0 2 2 1 0 zinc-ribbon family zf-C3HC4_5 PF17121.5 CDS31993.1 - 9.1 6.3 8.7 35 4.4 8.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 CDS31994.1 - 1e-69 234.8 0.0 1.3e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS31994.1 - 2.4e-33 115.5 0.0 3.2e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDS31994.1 - 4.3e-09 36.9 2.9 4.3e-09 36.9 2.9 2.8 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDS31994.1 - 6.1e-06 25.8 0.0 1.6e-05 24.3 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDS31994.1 - 0.00097 18.2 0.2 0.0014 17.7 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS31994.1 - 0.0038 16.6 0.1 0.0067 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS31994.1 - 0.0039 16.0 0.1 0.0063 15.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDS31994.1 - 0.032 13.9 0.0 5.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PHD PF00628.29 CDS31995.1 - 6.1e-23 80.5 16.1 2.2e-12 46.7 3.8 2.7 2 0 0 2 2 2 2 PHD-finger WAC_Acf1_DNA_bd PF10537.9 CDS31995.1 - 8e-23 80.9 0.1 2.8e-22 79.1 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CDS31995.1 - 1.3e-16 60.9 0.0 6.8e-16 58.6 0.0 2.4 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Bromodomain PF00439.25 CDS31995.1 - 2.7e-15 56.2 0.0 6.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Prok-RING_1 PF14446.6 CDS31995.1 - 4.8e-05 23.2 10.9 0.015 15.3 3.2 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CDS31995.1 - 0.00015 21.2 13.0 0.012 15.2 2.3 3.2 3 0 0 3 3 2 2 PHD-finger zf-RING_2 PF13639.6 CDS31995.1 - 0.097 13.0 21.6 0.79 10.1 8.0 2.7 2 0 0 2 2 2 0 Ring finger domain zf-HC5HC2H_2 PF13832.6 CDS31995.1 - 0.18 12.0 8.5 0.63 10.2 0.9 2.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_2 PF03107.16 CDS31995.1 - 0.2 12.0 16.4 1.4 9.3 5.7 3.3 3 0 0 3 3 3 0 C1 domain zf-HC5HC2H PF13771.6 CDS31995.1 - 0.23 11.7 15.7 1.2 9.5 1.8 3.1 2 1 1 3 3 3 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 CDS31995.1 - 0.43 10.2 12.0 3.2 7.4 2.8 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 CDS31995.1 - 6.9 6.9 20.2 1.8 8.7 7.0 3.8 3 1 0 3 3 3 0 KIAA1045 RING finger C1_1 PF00130.22 CDS31995.1 - 8.4 6.4 11.6 0.31 11.0 0.8 3.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Exo_endo_phos_2 PF14529.6 CDS31997.1 - 5.2e-12 45.7 0.5 8.8e-12 44.9 0.5 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_transf_7C PF02709.14 CDS31998.2 - 2.3e-19 68.8 0.5 4e-19 68.0 0.5 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDS31998.2 - 8.9e-11 41.6 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 VIT PF08487.10 CDS32001.1 - 8.8e-27 93.5 1.3 1.2e-26 93.1 0.1 1.9 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 CDS32001.1 - 1e-26 93.8 0.0 2e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CDS32001.1 - 9.8e-16 58.5 0.0 2.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDS32001.1 - 1.3e-13 51.5 0.0 2.4e-12 47.4 0.0 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain VIT_2 PF13757.6 CDS32001.1 - 2.7e-06 27.2 0.0 6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 CDS32001.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 CDS32001.1 - 0.0028 17.8 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF758 PF05527.11 CDS32001.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Cyclin_C PF02984.19 CDS32003.1 - 3.9e-08 33.4 0.4 9.4e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 CDS32003.1 - 0.019 14.7 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Cyclin, N-terminal domain TMEM190 PF15431.6 CDS32004.1 - 0.55 10.4 2.4 0.41 10.8 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 190 AAA PF00004.29 CDS32005.1 - 9.1e-27 94.1 0.0 1.4e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS32005.1 - 3e-06 27.6 0.1 2.8e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDS32005.1 - 3.4e-06 27.5 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CDS32005.1 - 4.5e-05 24.0 0.0 7.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDS32005.1 - 0.00042 20.4 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CDS32005.1 - 0.00051 20.0 0.0 0.82 9.5 0.0 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CDS32005.1 - 0.00067 19.7 0.0 0.0021 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CDS32005.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CDS32005.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDS32005.1 - 0.0025 18.0 0.0 0.0046 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CDS32005.1 - 0.0027 18.1 0.1 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin PF02224.18 CDS32005.1 - 0.003 17.3 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA_24 PF13479.6 CDS32005.1 - 0.0037 17.0 0.0 0.0074 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDS32005.1 - 0.0052 16.5 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDS32005.1 - 0.0056 16.6 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 CDS32005.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDS32005.1 - 0.0089 15.6 0.0 0.032 13.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 CDS32005.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 CDS32005.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CDS32005.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CDS32005.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CDS32005.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 CDS32005.1 - 0.041 13.1 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDS32005.1 - 0.065 13.6 0.1 0.22 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDS32005.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 CDS32005.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 CDS32005.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 CDS32005.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 CDS32005.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SCIFF PF13165.6 CDS32005.1 - 0.12 12.4 2.7 0.29 11.1 2.7 1.6 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF Ax_dynein_light PF10211.9 CDS32005.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain DUF2075 PF09848.9 CDS32005.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CDS32005.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 CDS32005.1 - 0.16 11.8 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 CDS32005.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDS32005.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 CDS32005.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDS32005.1 - 0.2 12.1 0.0 0.53 10.7 0.0 1.7 1 1 1 2 2 1 0 AAA domain Telomere_reg-2 PF10193.9 CDS32006.1 - 2.2e-19 69.9 0.0 7.8e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein Collagen PF01391.18 CDS32007.2 - 1.1e-157 511.9 677.3 5.6e-09 35.6 36.1 20.3 2 2 14 16 16 16 13 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CDS32007.2 - 5.6e-52 176.4 0.0 7.9e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Serpin PF00079.20 CDS32008.2 - 1.5e-77 261.4 0.1 1.8e-77 261.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDS32010.1 - 1.8e-09 37.4 0.0 2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDS32011.1 - 5.2e-15 55.6 0.1 5.9e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDS32012.1 - 4.3e-09 36.2 0.0 5.2e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 CDS32013.1 - 1.2e-06 28.1 0.2 2.2e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) 7tm_1 PF00001.21 CDS32014.2 - 4.1e-20 72.2 13.7 7.3e-20 71.4 13.7 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS32014.2 - 2e-18 66.8 11.0 3.1e-18 66.1 11.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CDS32014.2 - 0.0042 16.8 17.3 0.019 14.6 17.0 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2721 PF11026.8 CDS32014.2 - 0.35 10.8 0.1 0.35 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) EPL1 PF10513.9 CDS32015.1 - 2.3e-10 41.1 1.1 2.3e-10 41.1 1.1 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like Fasciclin PF02469.22 CDS32016.1 - 9.9e-27 93.7 0.0 5.6e-12 46.0 0.0 4.5 4 1 0 4 4 4 3 Fasciclin domain Cadherin PF00028.17 CDS32017.2 - 1.6e-288 932.3 0.5 9.4e-22 77.3 0.0 33.2 32 1 0 32 32 32 28 Cadherin domain Cadherin_2 PF08266.12 CDS32017.2 - 4.9e-20 71.2 0.0 0.047 13.5 0.0 10.6 11 0 0 11 11 11 5 Cadherin-like EGF PF00008.27 CDS32017.2 - 5.7e-18 64.9 47.4 3.3e-06 27.3 1.3 6.5 6 1 0 6 6 6 5 EGF-like domain hEGF PF12661.7 CDS32017.2 - 4.3e-09 36.7 36.4 0.00056 20.4 4.0 5.8 5 0 0 5 5 5 3 Human growth factor-like EGF Cadherin_pro PF08758.11 CDS32017.2 - 1.2e-07 31.8 0.0 0.73 10.0 0.0 6.1 5 1 0 5 5 5 2 Cadherin prodomain like Cadherin_3 PF16184.5 CDS32017.2 - 5.5e-05 23.1 21.8 2.9 7.9 0.0 12.6 15 0 0 15 15 15 2 Cadherin-like Laminin_G_2 PF02210.24 CDS32017.2 - 0.00086 19.9 0.1 0.016 15.8 0.0 3.1 2 1 0 2 2 2 1 Laminin G domain Cadherin_C_2 PF16492.5 CDS32017.2 - 0.038 14.7 0.1 0.13 13.1 0.1 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal EGF_2 PF07974.13 CDS32017.2 - 0.082 13.3 52.1 1.5 9.3 0.4 6.8 6 1 0 6 6 6 0 EGF-like domain DUF824 PF05688.11 CDS32017.2 - 7.7 6.4 5.6 1e+02 2.8 0.0 4.4 4 0 0 4 4 4 0 Salmonella repeat of unknown function (DUF824) DUF1822 PF08852.11 CDS32019.1 - 0.053 12.6 0.1 0.053 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) BRCA2 PF00634.18 CDS32019.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat Spt5_N PF11942.8 CDS32020.2 - 0.0087 17.0 3.0 0.011 16.6 3.0 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Radial_spoke PF04712.12 CDS32020.2 - 6.8 5.5 8.1 8.5 5.2 8.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PRIMA1 PF16101.5 CDS32022.2 - 0.26 11.3 11.2 0.24 11.5 8.3 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CDS32022.2 - 4.2 6.8 10.8 0.64 9.5 7.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Homeodomain PF00046.29 CDS32023.1 - 1.7e-10 40.5 0.7 3.3e-10 39.7 0.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 CDS32024.1 - 7.8e-22 76.9 3.4 1.8e-21 75.7 3.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32024.1 - 0.00058 19.7 0.0 0.0018 18.1 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CDS32024.1 - 0.054 13.0 0.1 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Fmp27_SW PF10305.9 CDS32024.1 - 0.11 13.2 0.0 24 5.7 0.0 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Homeodomain PF00046.29 CDS32025.2 - 7.5e-29 99.4 5.1 3e-19 68.6 6.5 2.8 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 CDS32025.2 - 4.4e-06 26.5 0.5 0.054 13.4 0.0 3.1 2 0 0 2 2 2 2 Homeobox KN domain Homez PF11569.8 CDS32025.2 - 0.0012 18.3 0.7 0.023 14.1 0.2 2.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez MSC PF09402.10 CDS32025.2 - 0.031 13.7 0.5 0.057 12.9 0.1 1.6 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF2209 PF09974.9 CDS32025.2 - 0.096 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DUF826 PF05696.11 CDS32026.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF826) TMEM100 PF16311.5 CDS32027.1 - 0.13 11.9 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 C2 PF00168.30 CDS32028.1 - 1.6e-91 301.4 0.3 1.6e-22 79.7 0.1 7.9 7 1 0 7 7 7 7 C2 domain FerB PF08150.12 CDS32028.1 - 8.6e-29 100.0 0.1 1.9e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 CDS32028.1 - 1.6e-26 93.1 0.6 2.5e-24 86.0 0.0 2.7 2 1 1 3 3 3 2 Ferlin C-terminus FerA PF08165.11 CDS32028.1 - 8.2e-20 70.5 0.2 1.6e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 FerA (NUC095) domain FerI PF08151.12 CDS32028.1 - 9.2e-09 35.3 0.0 2.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain Pex24p PF06398.11 CDS32028.1 - 2e-08 33.6 28.6 1e-06 28.0 3.6 3.8 3 1 1 4 4 4 2 Integral peroxisomal membrane peroxin dsRBD2 PF17842.1 CDS32028.1 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 PI3K_C2 PF00792.24 CDS32028.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Peptidase_M28 PF04389.17 CDS32029.1 - 5.1e-14 52.4 0.0 8.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 CDS32029.1 - 6.1e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Nicastrin DUF910 PF06014.11 CDS32029.1 - 0.037 14.0 0.9 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) Morc6_S5 PF17942.1 CDS32030.1 - 1e-23 84.0 3.3 1.5e-16 60.7 0.1 2.3 2 0 0 2 2 2 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 CDS32030.1 - 1.6e-13 50.4 6.9 3.8e-13 49.2 6.9 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c_3 PF13589.6 CDS32030.1 - 2.2e-08 34.0 0.4 7.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2870 PF11069.8 CDS32030.1 - 0.048 14.1 0.9 0.27 11.7 0.9 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Snapin_Pallidin PF14712.6 CDS32030.1 - 0.23 11.9 4.4 0.13 12.7 1.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF641 PF04859.12 CDS32030.1 - 1.9 8.8 9.1 0.19 12.1 1.3 2.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DMPK_coil PF08826.10 CDS32030.1 - 2.6 8.2 12.9 9.2 6.5 0.6 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like EPF PF17181.4 CDS32030.1 - 8.5 6.5 9.6 1 9.4 5.1 1.8 2 0 0 2 2 2 0 Epidermal patterning factor proteins PELOTA_1 PF15608.6 CDS32032.1 - 0.19 11.7 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Pkinase PF00069.25 CDS32033.1 - 4.2e-63 213.2 0.0 6.4e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Guanylate_kin PF00625.21 CDS32033.1 - 2.1e-57 193.8 0.0 5.9e-57 192.3 0.0 1.8 2 0 0 2 2 2 1 Guanylate kinase Pkinase_Tyr PF07714.17 CDS32033.1 - 2.1e-25 89.5 0.0 1.9e-17 63.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PDZ PF00595.24 CDS32033.1 - 2.2e-13 50.3 0.0 4.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3_2 PF07653.17 CDS32033.1 - 1.8e-08 34.0 0.0 4.3e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain L27 PF02828.16 CDS32033.1 - 3e-08 33.3 0.4 8.4e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 L27 domain PDZ_6 PF17820.1 CDS32033.1 - 3.9e-05 23.4 0.0 0.00014 21.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS32033.1 - 0.0041 16.7 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain Kdo PF06293.14 CDS32033.1 - 0.041 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CDS32033.1 - 0.077 12.5 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Synaptobrevin PF00957.21 CDS32034.1 - 3.5e-12 46.0 0.5 5.1e-12 45.4 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDS32034.1 - 4.8e-10 39.3 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Pkinase PF00069.25 CDS32035.1 - 2.1e-70 237.1 0.0 3.3e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32035.1 - 5.4e-32 111.1 0.0 7.9e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32035.1 - 1.5e-10 40.9 0.0 1.3e-08 34.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CDS32035.1 - 8.3e-06 25.3 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS32035.1 - 0.0032 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDS32035.1 - 0.004 16.2 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Rota_NS35 PF02509.14 CDS32035.1 - 0.0077 15.3 0.3 0.011 14.8 0.3 1.1 1 0 0 1 1 1 1 Rotavirus non-structural protein 35 RIO1 PF01163.22 CDS32035.1 - 0.014 15.0 1.9 0.032 13.8 1.9 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 CDS32035.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS32035.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TetR_C_27 PF17935.1 CDS32035.1 - 0.05 13.7 0.3 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1107 PF06526.12 CDS32035.1 - 0.12 12.3 0.4 15 5.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Troponin PF00992.20 CDS32036.1 - 1.1e-10 41.9 11.6 1.1e-10 41.9 11.6 2.4 2 0 0 2 2 2 1 Troponin T4_Rnl2_C PF18043.1 CDS32036.1 - 0.077 13.2 0.3 0.077 13.2 0.3 2.3 2 1 1 3 3 3 0 T4 RNA ligase 2 C-terminal Involucrin_N PF10583.9 CDS32036.1 - 0.17 12.5 2.8 0.76 10.4 2.8 2.1 1 1 0 1 1 1 0 Involucrin of squamous epithelia N-terminus LAG1-DNAbind PF09271.11 CDS32036.1 - 0.51 10.9 6.2 2 9.0 6.2 2.1 1 1 0 1 1 1 0 LAG1, DNA binding Tox-REase-5 PF15648.6 CDS32036.1 - 0.53 10.8 2.7 0.68 10.5 0.5 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 Aminopep PF10023.9 CDS32036.1 - 1.8 7.8 8.4 2.9 7.2 8.4 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Patatin PF01734.22 CDS32037.1 - 5.1e-13 49.7 0.3 2.5e-12 47.4 0.3 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Vps54 PF07928.12 CDS32037.1 - 0.00014 22.3 0.2 0.00035 21.0 0.2 1.7 1 0 0 1 1 1 1 Vps54-like protein VASt PF16016.5 CDS32038.2 - 9.2e-31 107.3 0.0 3.4e-30 105.5 0.0 2.0 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CDS32038.2 - 5e-22 77.9 4.0 1.3e-15 57.2 0.5 2.7 2 0 0 2 2 2 2 GRAM domain DUF3485 PF11984.8 CDS32038.2 - 0.097 12.4 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3485) UBD PF16455.5 CDS32038.2 - 0.13 12.5 0.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding domain Myosin_head PF00063.21 CDS32039.2 - 2.9e-222 739.6 1.9 5.7e-126 421.4 0.0 2.4 2 0 0 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.17 CDS32039.2 - 3.2e-59 198.1 0.6 1.2e-28 99.7 0.0 5.3 5 0 0 5 5 5 3 MyTH4 domain FERM_M PF00373.18 CDS32039.2 - 3.8e-08 33.7 0.0 1.1e-06 29.0 0.0 3.3 3 2 0 3 3 3 1 FERM central domain PI-PLC-Y PF00387.19 CDS32039.2 - 0.00033 21.0 1.8 1.3 9.3 0.1 3.2 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, Y domain IQ PF00612.27 CDS32039.2 - 0.0038 16.9 28.1 0.0055 16.4 0.5 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 CDS32039.2 - 0.0067 16.7 0.0 0.068 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF1411 PF07199.11 CDS32039.2 - 0.081 12.6 0.0 21 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) AAA_16 PF13191.6 CDS32039.2 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CDS32039.2 - 0.19 10.8 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-C4 PF00105.18 CDS32039.2 - 5.4 7.5 6.8 2.8 8.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C4 type (two domains) Ribosomal_S14 PF00253.21 CDS32041.1 - 1.6e-15 56.6 1.6 3e-15 55.7 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Pkinase PF00069.25 CDS32042.2 - 1.2e-22 80.6 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32042.2 - 9.2e-10 38.2 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32042.2 - 0.01 15.2 0.2 0.07 12.4 0.2 2.0 1 1 0 1 1 1 0 Kinase-like Biopterin_H PF00351.21 CDS32043.1 - 6.7e-152 505.3 0.2 8.3e-152 505.0 0.2 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Myb_DNA-bind_5 PF13873.6 CDS32045.1 - 2.4e-09 37.2 4.9 2.4e-09 37.2 4.9 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDS32045.1 - 2.2e-07 31.1 1.9 2.2e-07 31.1 1.9 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDS32045.1 - 0.0024 18.0 0.1 0.0064 16.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain LIDHydrolase PF10230.9 CDS32045.1 - 0.0059 16.2 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_chap PF03280.14 CDS32045.1 - 0.0089 16.0 3.4 0.016 15.2 0.1 2.2 2 0 0 2 2 2 1 Proteobacterial lipase chaperone protein DUF620 PF04788.12 CDS32045.1 - 0.009 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF620) Myb_DNA-bind_6 PF13921.6 CDS32045.1 - 0.027 14.7 0.2 0.057 13.7 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain HEPN_AbiV PF18728.1 CDS32045.1 - 0.031 14.4 0.6 0.058 13.5 0.3 1.7 2 0 0 2 2 2 0 AbiV DUF3605 PF12239.8 CDS32045.1 - 0.046 14.1 2.7 0.22 11.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) Stathmin PF00836.19 CDS32045.1 - 0.28 11.2 5.6 0.62 10.0 0.7 2.3 2 0 0 2 2 2 0 Stathmin family Erf4 PF10256.9 CDS32046.1 - 1.7e-12 47.4 0.0 4.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Myb_DNA-bind_5 PF13873.6 CDS32046.1 - 6.7e-07 29.3 3.1 1.9e-06 27.9 3.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDS32046.1 - 1.2e-06 28.8 2.1 2.6e-06 27.7 2.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain IMD PF08397.11 CDS32046.1 - 0.0047 16.3 2.2 0.0047 16.3 2.2 1.9 2 0 0 2 2 2 1 IRSp53/MIM homology domain Myb_DNA-binding PF00249.31 CDS32046.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS32046.1 - 0.083 13.2 0.5 0.19 12.0 0.5 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 CDS32046.1 - 3.2 8.2 8.7 0.34 11.3 2.2 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4487 PF14868.6 CDS32047.1 - 4.7e-18 65.3 2.0 6.3e-18 64.9 1.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4487) Tyr_Deacylase PF02580.16 CDS32048.1 - 4.2e-54 183.0 0.1 4.8e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase rve PF00665.26 CDS32049.1 - 0.0013 18.9 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDS32049.1 - 0.0081 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PDZ PF00595.24 CDS32050.1 - 2.5e-15 56.6 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS32050.1 - 5.1e-06 26.2 0.0 9.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS32050.1 - 0.00025 21.3 0.0 0.00037 20.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain LYRIC PF15686.5 CDS32052.1 - 0.00091 18.9 4.1 0.0011 18.6 4.1 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Peptidase_S49_N PF08496.10 CDS32052.1 - 0.0029 17.7 1.2 0.0037 17.3 1.2 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal TMEMspv1-c74-12 PF11044.8 CDS32052.1 - 0.0034 17.3 0.6 0.0034 17.3 0.6 2.2 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4834 PF16118.5 CDS32052.1 - 0.0039 18.1 0.8 0.0065 17.4 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) V_ATPase_I PF01496.19 CDS32052.1 - 0.0075 14.3 0.4 0.0085 14.1 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Gag_p15 PF08723.10 CDS32052.1 - 0.0078 16.4 0.2 0.021 15.0 0.1 1.7 2 0 0 2 2 2 1 Gag protein p15 7tm_2 PF00002.24 CDS32052.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Sigma_reg_N PF13800.6 CDS32052.1 - 0.013 15.8 0.2 0.023 15.0 0.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SIT PF15330.6 CDS32052.1 - 0.017 15.5 3.9 0.051 14.0 3.9 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.6 CDS32052.1 - 0.028 14.3 2.6 0.028 14.3 2.6 1.9 1 1 1 2 2 2 0 TMEM154 protein family EMC3_TMCO1 PF01956.16 CDS32052.1 - 0.036 13.8 2.7 0.073 12.8 2.6 1.5 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CD34_antigen PF06365.12 CDS32052.1 - 0.043 13.4 0.2 0.056 13.0 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4446 PF14584.6 CDS32052.1 - 0.048 13.7 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Tmemb_9 PF05434.11 CDS32052.1 - 0.055 13.4 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 TMEM9 DUF2254 PF10011.9 CDS32052.1 - 0.057 12.2 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Shisa PF13908.6 CDS32052.1 - 0.069 13.4 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CDS32052.1 - 0.07 11.5 0.0 0.077 11.4 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2561 PF10812.8 CDS32052.1 - 0.083 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PIG-P PF08510.12 CDS32052.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PIG-P Myc_target_1 PF15179.6 CDS32052.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Myc target protein 1 OAD_gamma PF04277.13 CDS32052.1 - 0.16 12.6 8.3 7.7 7.2 8.3 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 CDS32052.1 - 0.24 12.3 2.0 0.45 11.4 2.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRRC37AB_C PF14914.6 CDS32052.1 - 0.79 9.6 4.8 0.35 10.8 0.7 2.0 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Phage_Gp23 PF10669.9 CDS32052.1 - 1.4 9.3 9.3 4.9 7.5 9.3 2.0 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OSTbeta PF15048.6 CDS32052.1 - 3.5 7.8 6.1 12 6.1 6.0 2.1 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Exo_endo_phos_2 PF14529.6 CDS32053.1 - 3.9e-06 26.7 0.1 8.2e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase OST3_OST6 PF04756.13 CDS32055.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family LMBR1 PF04791.16 CDS32056.1 - 0.17 10.8 1.1 0.24 10.2 1.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Chorion_2 PF03964.15 CDS32057.1 - 0.012 16.5 2.1 0.012 16.5 2.1 2.1 2 1 0 2 2 2 0 Chorion family 2 IMPDH PF00478.25 CDS32058.2 - 1.2e-133 445.4 0.5 1.4e-133 445.1 0.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDS32058.2 - 1.2e-12 48.0 0.1 9.4e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CDS32058.2 - 3.1e-12 46.5 1.2 1.9e-08 34.1 1.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CDS32058.2 - 3.4e-10 39.5 3.3 2.9e-09 36.4 1.2 2.4 3 0 0 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CDS32058.2 - 6.7e-06 25.7 1.1 0.00024 20.6 0.1 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CDS32058.2 - 1.6e-05 24.3 0.8 3.2e-05 23.4 0.8 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 CDS32058.2 - 0.00064 19.0 1.1 0.0053 16.0 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF561) Glu_synthase PF01645.17 CDS32058.2 - 0.0076 15.4 1.9 0.015 14.5 1.9 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.14 CDS32058.2 - 0.011 14.9 1.4 1.2 8.3 1.4 2.5 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 CDS32058.2 - 0.021 14.1 2.4 0.041 13.1 0.6 2.3 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 CDS32058.2 - 0.024 14.0 1.2 0.88 9.0 0.2 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Aldolase PF01081.19 CDS32058.2 - 0.03 13.7 1.0 0.78 9.1 0.1 2.7 2 1 2 4 4 4 0 KDPG and KHG aldolase Dus PF01207.17 CDS32058.2 - 0.033 13.3 0.1 0.078 12.1 0.1 1.5 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Pacs-1 PF10254.9 CDS32059.1 - 4.8e-45 154.3 0.0 2e-22 79.8 0.0 4.0 3 1 0 3 3 3 3 PACS-1 cytosolic sorting protein SR-25 PF10500.9 CDS32062.1 - 0.041 13.5 11.1 0.06 12.9 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PDH PF02153.17 CDS32062.1 - 0.15 11.0 3.0 0.19 10.7 3.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF755 PF05501.11 CDS32062.1 - 0.6 10.4 13.2 1.1 9.5 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-UBR PF02207.20 CDS32063.1 - 0.0021 18.2 0.8 0.004 17.3 0.8 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) LCM PF04072.14 CDS32065.1 - 7.3e-19 68.4 0.0 1.4e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_32 PF13679.6 CDS32065.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Lipase_GDSL_2 PF13472.6 CDS32066.1 - 7e-10 39.6 0.0 8.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDS32066.1 - 3e-06 27.3 0.0 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CDS32066.1 - 0.00094 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CDC45 PF02724.14 CDS32066.1 - 0.092 11.0 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1848 PF08902.11 CDS32066.1 - 0.15 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) dCMP_cyt_deam_1 PF00383.23 CDS32066.1 - 0.17 11.8 0.0 0.87 9.5 0.0 2.0 1 1 1 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1241 PF06840.11 CDS32067.1 - 5.9e-17 61.7 0.0 1.5e-13 50.6 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1241) DUF1358 PF07096.11 CDS32068.1 - 0.00042 20.3 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) WD40 PF00400.32 CDS32069.1 - 4.5e-29 100.1 13.6 4.6e-06 27.3 0.2 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.12 CDS32069.1 - 2.2e-27 96.5 1.6 3.6e-27 95.9 1.6 1.4 1 0 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 CDS32069.1 - 2.8e-10 40.3 0.1 0.017 15.4 0.0 5.2 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS32069.1 - 2.4e-05 23.2 0.6 0.31 9.7 0.0 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CDS32069.1 - 0.00088 18.9 1.2 0.058 13.0 0.0 3.4 3 1 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.11 CDS32069.1 - 0.0022 16.8 0.0 3.4 6.3 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like MDMPI_C PF07398.11 CDS32069.1 - 0.54 11.2 6.2 3.1 8.7 0.0 3.5 4 0 0 4 4 4 0 MDMPI C-terminal domain Pkinase PF00069.25 CDS32070.1 - 3e-49 167.8 0.0 3.4e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32070.1 - 1.4e-34 119.6 0.0 1.7e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS32070.1 - 0.00067 18.7 0.0 0.016 14.1 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 CDS32070.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDS32070.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CDS32070.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDS32070.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Transposase_1 PF01359.18 CDS32071.1 - 0.018 14.9 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Transposase (partial DDE domain) HTH_24 PF13412.6 CDS32071.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Dot_icm_IcmQ PF09475.10 CDS32071.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) TPR_2 PF07719.17 CDS32072.1 - 1.8e-26 90.1 0.0 2.2e-06 27.3 0.2 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32072.1 - 8.9e-24 82.3 1.5 4.1e-07 29.5 0.3 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat DnaJ PF00226.31 CDS32072.1 - 5.8e-19 68.0 2.0 9.3e-19 67.3 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.6 CDS32072.1 - 1.1e-18 66.3 0.5 0.00037 21.1 0.1 6.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32072.1 - 4.2e-18 65.6 0.5 2.9e-05 24.5 0.2 5.1 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS32072.1 - 7.6e-17 60.1 3.1 2.7e-06 27.1 0.2 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32072.1 - 2.6e-13 49.3 0.1 0.0029 17.9 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32072.1 - 5.5e-13 49.3 0.0 0.0061 17.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32072.1 - 6.6e-12 45.6 1.3 0.0007 19.8 0.1 5.4 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32072.1 - 1.2e-08 35.0 0.0 0.0019 18.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS32072.1 - 1.8e-08 33.9 6.8 0.0024 17.5 0.3 5.5 5 2 2 7 7 7 3 TPR repeat TPR_6 PF13174.6 CDS32072.1 - 3.3e-08 33.6 0.8 0.028 15.1 0.2 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDS32072.1 - 4.6e-08 32.7 0.1 0.0068 16.3 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32072.1 - 2.6e-07 30.8 0.1 0.17 12.2 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDS32072.1 - 4.8e-06 26.2 0.2 0.0039 17.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CDS32072.1 - 0.00035 20.9 3.9 1.1 9.6 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS32072.1 - 0.013 14.9 0.0 8.6 5.6 0.0 3.0 2 1 1 3 3 3 0 MalT-like TPR region TPR_15 PF13429.6 CDS32072.1 - 0.014 14.7 0.6 16 4.6 0.3 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 CDS32072.1 - 0.018 15.3 0.1 0.16 12.3 0.0 2.8 2 0 0 2 2 1 0 PPR repeat TPR_3 PF07720.12 CDS32072.1 - 0.021 14.8 0.9 3.1 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDS32072.1 - 0.023 15.2 0.1 10 6.5 0.0 3.4 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation RPT PF13446.6 CDS32072.1 - 0.025 14.5 0.1 0.29 11.1 0.1 2.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein Glyoxalase_2 PF12681.7 CDS32072.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain SRP_TPR_like PF17004.5 CDS32072.1 - 0.053 13.5 3.4 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Putative TPR-like repeat DUF2460 PF09343.10 CDS32072.1 - 0.17 11.4 0.2 0.33 10.4 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) Seryl_tRNA_N PF02403.22 CDS32072.1 - 0.19 12.0 6.2 0.048 13.9 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fis1_TPR_C PF14853.6 CDS32072.1 - 0.52 10.4 8.1 3 8.0 0.8 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Methyltransf_31 PF13847.6 CDS32073.1 - 5.7e-15 55.4 0.4 2.5e-14 53.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS32073.1 - 3.6e-10 40.5 0.2 1.1e-09 38.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS32073.1 - 7e-09 36.3 0.0 2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS32073.1 - 3.5e-06 27.6 0.0 8.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS32073.1 - 2.4e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDS32073.1 - 0.00026 21.0 0.0 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDS32073.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 CDS32073.1 - 0.092 12.3 0.1 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) PCMT PF01135.19 CDS32073.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.32 CDS32074.1 - 1.6e-39 133.2 10.4 7e-08 33.0 0.7 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32074.1 - 2e-17 63.3 0.7 0.00094 19.4 0.0 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain SH2 PF00017.24 CDS32074.1 - 1.4e-12 47.5 0.1 2e-11 43.8 0.0 2.8 3 0 0 3 3 3 1 SH2 domain Ge1_WD40 PF16529.5 CDS32074.1 - 1.9e-08 33.7 1.0 0.0012 17.9 0.1 4.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS32074.1 - 7.1e-07 29.3 0.0 0.034 14.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CDS32074.1 - 0.00097 18.6 0.5 10 5.4 0.0 4.0 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDS32074.1 - 0.0073 15.0 3.5 0.23 10.0 0.1 3.4 3 1 0 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CDS32074.1 - 0.044 12.3 0.1 4.4 5.7 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain Hydrolase_6 PF13344.6 CDS32075.2 - 6.2e-09 35.9 0.0 1.9e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDS32075.2 - 0.00023 21.1 0.1 24 5.1 0.0 4.5 4 1 0 4 4 4 3 HAD-hyrolase-like Profilin PF00235.19 CDS32076.1 - 5.6e-08 33.1 0.0 6.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Profilin Clathrin PF00637.20 CDS32077.1 - 1.3e-201 660.6 43.2 9.4e-33 113.1 3.4 8.1 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CDS32077.1 - 7.8e-31 104.9 5.3 2.5e-07 30.6 0.0 6.5 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 CDS32077.1 - 1.9e-30 104.6 0.4 1e-29 102.2 0.1 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 CDS32077.1 - 3.8e-10 38.9 0.1 1.4e-09 37.1 0.1 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CDS32077.1 - 2.4e-06 26.9 10.9 0.0012 17.9 0.2 4.6 5 0 0 5 5 5 2 Coatomer WD associated region TPR_2 PF07719.17 CDS32077.1 - 0.0015 18.5 5.3 1.4 9.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS32077.1 - 0.02 14.9 17.4 0.67 10.1 0.4 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32077.1 - 0.027 15.3 26.4 11 7.2 0.0 9.7 9 1 2 11 11 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32077.1 - 0.076 13.2 8.4 23 5.3 0.1 6.5 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDS32077.1 - 0.23 11.4 8.1 5 7.1 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS32077.1 - 0.58 10.1 4.2 2.8 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CDS32078.2 - 2.9e-45 154.2 0.0 6.2e-45 153.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS32078.2 - 2.1e-22 79.6 0.0 7.8e-22 77.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CDS32078.2 - 5.3e-14 52.2 0.7 5.3e-14 52.2 0.7 4.7 4 0 0 4 4 4 1 DBP10CT (NUC160) domain DUF5386 PF17360.2 CDS32078.2 - 0.0036 17.2 9.1 0.16 11.9 0.2 2.7 3 0 0 3 3 3 2 Family of unknown function (DUF5386) DUF1796 PF08795.10 CDS32078.2 - 0.0073 16.3 0.3 7.3 6.5 0.0 2.9 3 0 0 3 3 3 2 Putative papain-like cysteine peptidase (DUF1796) 2-oxogl_dehyd_N PF16078.5 CDS32078.2 - 0.0086 15.6 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 2-oxoglutarate dehydrogenase N-terminus PYC_OADA PF02436.18 CDS32078.2 - 0.068 12.9 2.2 6.2 6.5 0.1 2.6 2 0 0 2 2 2 0 Conserved carboxylase domain DUF1752 PF08550.10 CDS32078.2 - 0.7 9.8 4.5 21 5.1 0.4 3.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Cadherin PF00028.17 CDS32079.2 - 6.9e-46 154.6 2.4 1.3e-14 54.4 0.1 7.0 7 0 0 7 7 7 5 Cadherin domain Cadherin_3 PF16184.5 CDS32079.2 - 5.5e-08 32.8 9.5 0.01 15.8 0.1 5.2 5 0 0 5 5 5 4 Cadherin-like Cadherin_4 PF17803.1 CDS32079.2 - 8.4e-05 23.1 8.5 0.33 11.6 0.0 4.9 5 0 0 5 5 5 3 Bacterial cadherin-like domain Cadherin_2 PF08266.12 CDS32079.2 - 0.0026 17.5 1.2 23 4.9 0.2 3.7 4 0 0 4 4 4 2 Cadherin-like Tad PF13400.6 CDS32079.2 - 2 8.8 5.0 3.9 7.9 5.0 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Yip1 PF04893.17 CDS32082.1 - 1.7e-13 50.6 10.1 3.8e-13 49.5 10.1 1.5 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CDS32082.1 - 0.0095 15.7 3.0 0.015 15.1 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) UPF0139 PF03669.13 CDS32082.1 - 0.022 14.6 0.3 0.066 13.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF1189 PF06691.11 CDS32082.1 - 8 6.0 5.7 14 5.2 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) RRM_1 PF00076.22 CDS32084.2 - 0.0018 18.1 1.7 1.2 9.0 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PID PF00640.23 CDS32085.2 - 3.6e-13 49.8 0.3 6.6e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 CDS32085.2 - 1.5e-11 44.2 0.0 6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 SH2 domain PTB PF08416.13 CDS32085.2 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Pkinase PF00069.25 CDS32086.2 - 2.8e-42 144.9 0.0 4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32086.2 - 8.3e-29 100.6 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS32086.2 - 0.048 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CDS32086.2 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Clathrin PF00637.20 CDS32089.1 - 3.4e-14 52.9 0.2 1.5e-13 50.8 0.2 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 CDS32089.1 - 0.00011 22.9 0.0 0.0012 19.7 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 CDS32089.1 - 0.00025 21.0 1.9 0.00025 21.0 1.9 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS32089.1 - 0.00029 20.6 1.0 0.00029 20.6 1.0 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS32089.1 - 0.00086 19.5 0.7 0.00086 19.5 0.7 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDS32089.1 - 0.0011 19.2 2.0 0.0011 19.2 2.0 2.9 4 0 0 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 CDS32089.1 - 0.0032 17.2 1.4 0.012 15.3 1.4 2.1 1 0 0 1 1 1 1 RING-like zinc finger ANAPC4_WD40 PF12894.7 CDS32089.1 - 0.011 16.0 0.0 0.062 13.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Vps39_2 PF10367.9 CDS32089.1 - 0.017 15.5 1.7 0.096 13.1 1.7 2.2 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 CDS32089.1 - 0.15 12.1 8.3 0.016 15.1 3.2 2.2 2 1 0 2 2 2 0 zinc-RING finger domain GATase_5 PF13507.6 CDS32089.1 - 0.18 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFMR_assoc PF16596.5 CDS32089.1 - 0.31 11.5 2.0 0.74 10.3 2.0 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR zf-ANAPC11 PF12861.7 CDS32089.1 - 0.37 10.9 3.4 1.8 8.7 3.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CDS32089.1 - 0.4 10.6 10.1 0.28 11.1 5.1 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.10 CDS32089.1 - 1.6 9.2 6.0 4.5 7.7 6.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Vps26 PF03643.15 CDS32090.2 - 9.1e-173 572.6 6.8 9.7e-107 356.1 0.9 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CDS32090.2 - 9.1e-07 29.4 0.0 0.00053 20.4 0.0 4.0 5 0 0 5 5 5 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDS32090.2 - 5.5e-05 23.2 2.1 2.4 8.2 0.0 4.4 3 1 1 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Alveol-reg_P311 PF11092.8 CDS32090.2 - 0.0047 17.0 0.6 17 5.6 0.0 3.9 4 0 0 4 4 4 2 Neuronal protein 3.1 (p311) DUF600 PF04634.12 CDS32090.2 - 0.016 15.2 1.7 7 6.7 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF600 FISNA PF14484.6 CDS32090.2 - 0.018 15.2 0.5 14 6.0 0.1 3.0 2 0 0 2 2 2 0 Fish-specific NACHT associated domain TT_ORF1 PF02956.14 CDS32090.2 - 0.23 10.1 6.9 2.6 6.6 0.8 2.2 2 0 0 2 2 2 0 TT viral orf 1 NfI_DNAbd_pre-N PF10524.9 CDS32090.2 - 0.3 11.0 2.0 21 5.1 0.2 2.5 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus DUF3276 PF11680.8 CDS32090.2 - 0.8 9.8 12.8 1.5 8.9 0.1 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3276) Jnk-SapK_ap_N PF09744.9 CDS32092.2 - 2.4e-22 79.8 9.1 2.4e-22 79.8 9.1 3.3 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 CDS32092.2 - 0.0085 16.2 21.5 0.16 12.1 6.3 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus HCMV_UL139 PF12507.8 CDS32092.2 - 0.015 15.6 1.1 0.015 15.6 1.1 2.2 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein FapA PF03961.13 CDS32092.2 - 0.068 11.8 12.8 0.084 11.5 2.2 2.8 2 1 0 3 3 3 0 Flagellar Assembly Protein A LPP PF04728.13 CDS32092.2 - 0.12 12.8 8.7 0.92 10.0 0.3 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF3450 PF11932.8 CDS32092.2 - 0.47 9.7 14.5 3.4 6.9 7.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 CDS32092.2 - 1.4 9.6 18.4 3.2 8.5 3.2 4.5 3 2 2 5 5 5 0 Initiation control protein YabA CENP-H PF05837.12 CDS32092.2 - 2.3 8.6 26.9 0.16 12.4 3.3 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 CDS32092.2 - 2.6 8.3 19.5 1.6 9.0 1.2 4.3 3 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Mto2_bdg PF12808.7 CDS32094.1 - 0.0035 17.6 0.8 0.0035 17.6 0.8 3.5 3 1 1 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region RPW8 PF05659.11 CDS32094.1 - 0.0072 16.0 1.1 0.0072 16.0 1.1 2.2 1 1 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 KASH_CCD PF14662.6 CDS32094.1 - 0.027 14.3 23.2 0.026 14.4 8.9 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 CDS32094.1 - 0.036 13.0 20.4 0.042 12.7 7.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HAP1_N PF04849.13 CDS32094.1 - 0.049 12.8 21.2 0.15 11.3 13.3 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF1796 PF08795.10 CDS32094.1 - 0.056 13.4 1.4 0.1 12.5 1.4 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Herpes_BLRF2 PF05812.12 CDS32094.1 - 0.063 13.4 4.1 1.2 9.3 1.2 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein GAS PF13851.6 CDS32094.1 - 0.08 12.3 20.8 0.55 9.6 7.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 CDS32094.1 - 0.098 12.8 0.4 0.098 12.8 0.4 4.1 2 1 2 4 4 4 0 bZIP transcription factor ATG16 PF08614.11 CDS32094.1 - 0.12 12.6 19.9 0.041 14.1 13.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UpxZ PF06603.11 CDS32094.1 - 0.13 12.6 4.8 1.6 9.0 3.0 2.7 1 1 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists PRKG1_interact PF15898.5 CDS32094.1 - 0.17 12.8 19.1 0.055 14.4 14.9 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 CDS32094.1 - 0.19 11.1 7.4 0.25 10.6 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Scaffolding_pro PF11418.8 CDS32094.1 - 0.27 11.8 6.0 6.9 7.3 0.1 3.2 1 1 1 3 3 3 0 Phi29 scaffolding protein Tup_N PF08581.10 CDS32094.1 - 0.36 11.2 14.0 3 8.2 7.3 2.9 2 1 0 2 2 2 0 Tup N-terminal Fez1 PF06818.15 CDS32094.1 - 0.48 10.9 13.9 0.7 10.3 13.9 1.3 1 0 0 1 1 1 0 Fez1 HALZ PF02183.18 CDS32094.1 - 0.69 10.2 9.7 6.2 7.1 0.6 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4201 PF13870.6 CDS32094.1 - 0.93 9.2 21.3 1.1 9.0 15.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 CDS32094.1 - 1.3 9.2 18.7 0.56 10.4 12.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 CDS32094.1 - 1.3 9.5 12.7 0.99 9.9 4.7 2.7 2 1 0 2 2 2 0 Spectrin repeat TMF_TATA_bd PF12325.8 CDS32094.1 - 1.6 9.0 18.5 8.3 6.7 0.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BBP1_C PF15272.6 CDS32094.1 - 2.2 8.0 15.7 6.2 6.6 6.9 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.11 CDS32094.1 - 3.4 8.1 11.2 3.4 8.1 0.6 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CDS32094.1 - 3.4 7.5 18.0 3.1 7.6 1.6 3.7 1 1 2 4 4 4 0 Septum formation initiator Csm1_N PF18504.1 CDS32094.1 - 3.9 7.9 19.0 0.69 10.3 1.3 3.4 3 1 0 3 3 3 0 Csm1 N-terminal domain zf-C4H2 PF10146.9 CDS32094.1 - 4.4 7.6 12.5 60 3.9 12.5 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.11 CDS32094.1 - 4.8 5.9 20.6 0.034 13.0 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) C2 PF00168.30 CDS32095.1 - 1.2e-17 64.1 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 C2 domain Aida_C2 PF14186.6 CDS32095.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal adhesion Serpin PF00079.20 CDS32096.1 - 3.6e-17 62.7 0.0 4.4e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Glyco_transf_7N PF13733.6 CDS32098.1 - 2.2e-20 72.7 0.1 3.8e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CDS32098.1 - 1.3e-16 60.0 0.8 2.2e-16 59.3 0.8 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase LRR_4 PF12799.7 CDS32099.2 - 2.4e-11 43.7 8.3 0.012 16.1 0.4 6.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDS32099.2 - 2.1e-06 27.3 13.3 0.56 10.4 0.0 7.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.6 CDS32099.2 - 0.0022 17.7 3.8 4.8 7.0 0.1 4.3 3 2 2 5 5 5 4 Leucine rich repeat FTH PF01827.27 CDS32099.2 - 0.03 14.1 0.6 19 5.0 0.0 3.5 4 0 0 4 4 4 0 FTH domain TFB6 PF17110.5 CDS32099.2 - 0.062 13.0 0.0 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH MIT PF04212.18 CDS32099.2 - 0.14 12.2 0.0 0.57 10.3 0.0 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain HSP20 PF00011.21 CDS32101.1 - 2.2e-18 66.3 0.0 7.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF2045 PF09741.9 CDS32102.2 - 1.7e-72 243.6 0.0 2.6e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Proteasome PF00227.26 CDS32102.2 - 1.5e-57 194.2 0.0 2.3e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDS32102.2 - 0.0079 15.9 1.3 0.015 14.9 1.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Aquarius_N PF16399.5 CDS32103.1 - 4e-209 696.6 0.8 4.9e-170 567.3 0.1 2.5 1 1 1 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CDS32103.1 - 5.7e-29 101.7 0.0 3.9e-28 98.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CDS32103.1 - 2.3e-27 95.9 0.0 5.5e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS32103.1 - 1.7e-08 34.9 0.0 2.2e-07 31.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDS32103.1 - 2.6e-08 33.8 0.0 5.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CDS32103.1 - 1e-05 25.6 0.1 6.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CDS32103.1 - 0.00032 20.3 0.1 0.0037 16.9 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CDS32103.1 - 0.0037 16.7 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein RecA PF00154.21 CDS32103.1 - 0.0038 16.7 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 CDS32103.1 - 0.0083 16.5 0.2 0.2 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 CDS32103.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 CDS32103.1 - 0.038 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 CDS32103.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CDS32103.1 - 0.041 13.7 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CDS32103.1 - 0.055 13.7 0.1 0.62 10.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain DnaB_C PF03796.15 CDS32103.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 CDS32103.1 - 0.16 11.1 0.5 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 CDS32103.1 - 0.25 10.5 0.6 0.83 8.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Alg14 PF08660.11 CDS32104.1 - 7e-57 192.2 0.1 8.2e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GTP_EFTU PF00009.27 CDS32105.1 - 1.2e-60 204.4 0.1 1.8e-60 203.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDS32105.1 - 6.7e-31 106.6 0.0 5e-30 103.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDS32105.1 - 7.9e-23 80.3 0.0 2e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDS32105.1 - 1e-14 54.7 0.2 8.4e-14 51.7 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CDS32105.1 - 7.4e-14 51.6 0.0 1.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CDS32105.1 - 0.00045 20.3 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PBP1_TM PF14812.6 CDS32108.1 - 0.00028 21.2 0.3 0.00028 21.2 0.3 3.0 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SPC22 PF04573.12 CDS32113.1 - 4.1e-53 179.4 0.1 4.6e-53 179.2 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DNA_pol3_delta2 PF13177.6 CDS32114.1 - 1.6e-11 44.3 0.1 3.3e-11 43.2 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CDS32114.1 - 6.9e-08 33.0 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDS32114.1 - 2.1e-07 31.0 0.1 3.3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CDS32114.1 - 0.00042 20.1 0.2 0.28 10.9 0.0 2.4 1 1 1 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS32114.1 - 0.00061 20.2 0.1 0.027 14.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 CDS32114.1 - 0.0034 17.2 0.6 0.38 10.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDS32114.1 - 0.0064 16.8 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDS32114.1 - 0.014 14.8 0.0 0.07 12.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS32114.1 - 0.015 15.3 0.2 0.12 12.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDS32114.1 - 0.031 14.0 0.1 0.066 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CDS32114.1 - 0.037 14.2 0.1 0.17 12.0 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Resolvase PF00239.21 CDS32114.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_19 PF13245.6 CDS32114.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_2 PF13923.6 CDS32115.1 - 8.8e-10 38.3 6.5 2.1e-09 37.1 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS32115.1 - 1.6e-08 34.3 7.6 4e-08 33.0 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 CDS32115.1 - 2.5e-07 31.3 0.4 6e-07 30.0 0.3 1.8 2 0 0 2 2 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 CDS32115.1 - 6.3e-06 26.4 7.0 1.7e-05 25.1 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDS32115.1 - 3.5e-05 23.6 5.2 9.2e-05 22.2 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS32115.1 - 6e-05 23.2 2.7 0.00015 22.0 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS32115.1 - 0.00051 19.9 10.3 0.0013 18.7 9.3 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CDS32115.1 - 0.0013 18.4 1.5 0.0042 16.8 1.5 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CDS32115.1 - 0.0017 18.5 8.5 0.0049 17.0 8.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CDS32115.1 - 0.038 14.0 1.4 0.085 12.9 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDS32115.1 - 0.056 13.3 13.1 0.21 11.5 11.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDS32115.1 - 0.074 12.9 3.1 0.23 11.3 3.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 CDS32115.1 - 0.51 10.5 4.4 1.2 9.2 4.4 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.7 CDS32115.1 - 0.75 9.9 6.1 3.2 7.8 6.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 CDS32115.1 - 2 8.5 11.0 5.8 7.0 9.9 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.6 CDS32115.1 - 4.1 7.3 10.6 1.4 8.8 6.7 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein HSP90 PF00183.18 CDS32117.1 - 7.4e-98 328.7 0.5 7.1e-96 322.2 0.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CDS32117.1 - 1.3e-10 41.3 0.1 2.2e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDS32117.1 - 2.1e-07 31.4 0.1 3.8e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_C PF00137.21 CDS32119.1 - 6.2e-28 96.9 35.1 6.2e-20 71.3 15.7 2.4 3 0 0 3 3 3 2 ATP synthase subunit C DUF2970 PF11174.8 CDS32119.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) zf-met PF12874.7 CDS32120.1 - 0.034 14.6 0.5 0.034 14.6 0.5 5.1 5 1 0 5 5 5 0 Zinc-finger of C2H2 type UPF0016 PF01169.19 CDS32121.1 - 1.5e-41 140.5 21.3 4.1e-23 81.5 3.4 2.5 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 TerC PF03741.16 CDS32121.1 - 0.14 11.8 9.0 0.15 11.7 1.7 2.5 2 1 1 3 3 3 0 Integral membrane protein TerC family 7tm_1 PF00001.21 CDS32122.1 - 4.8e-13 49.0 9.2 4.8e-13 49.0 9.2 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF2306 PF10067.9 CDS32122.1 - 0.36 11.0 6.0 6.6 6.9 0.2 3.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) SIP1 PF04938.12 CDS32123.1 - 2.9e-16 59.9 0.2 3.3e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2247 PF10004.9 CDS32123.1 - 0.026 14.3 0.3 0.061 13.1 0.1 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) PMC2NT PF08066.12 CDS32123.1 - 0.11 13.2 0.4 9.3 7.0 0.2 3.0 2 1 0 3 3 3 0 PMC2NT (NUC016) domain LRR_6 PF13516.6 CDS32125.1 - 2.3e-28 95.8 20.4 3e-05 23.7 0.0 11.6 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.7 CDS32125.1 - 7.3e-11 42.1 6.3 0.0022 18.4 0.0 6.3 4 3 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS32125.1 - 0.0015 18.8 21.6 4 8.4 0.0 9.6 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 CDS32125.1 - 0.0022 17.7 0.9 0.42 10.4 0.0 4.4 5 2 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.6 CDS32126.1 - 3.2e-11 42.8 14.3 4.7e-07 29.5 4.5 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDS32126.1 - 1.7e-08 34.6 13.3 1.5e-06 28.4 0.1 3.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS32126.1 - 0.001 19.3 7.3 1.7 9.5 0.0 4.8 3 1 0 3 3 3 2 Leucine Rich Repeat DUF148 PF02520.17 CDS32126.1 - 0.016 15.3 0.6 0.041 14.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF148 LRR_9 PF14580.6 CDS32126.1 - 0.025 14.1 0.6 0.025 14.1 0.6 2.3 2 1 0 2 2 2 0 Leucine-rich repeat Homeodomain PF00046.29 CDS32127.1 - 1.2e-21 76.3 5.9 2.7e-21 75.2 5.9 1.6 1 0 0 1 1 1 1 Homeodomain DAGK_cat PF00781.24 CDS32129.1 - 2.1e-23 82.3 0.0 3.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DHC_N1 PF08385.12 CDS32130.1 - 4.7e-125 418.4 8.6 4.7e-125 418.4 8.6 2.7 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CDS32130.1 - 2.1e-05 23.8 3.1 2.1e-05 23.8 3.1 4.3 4 2 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 3H PF02829.14 CDS32130.1 - 0.088 13.1 0.1 0.47 10.8 0.1 2.3 1 0 0 1 1 1 0 3H domain DUF496 PF04363.12 CDS32130.1 - 0.8 9.8 5.1 1.3 9.1 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF496) Phosphodiest PF01663.22 CDS32131.1 - 5.3e-58 197.3 3.8 3.9e-53 181.3 0.4 2.0 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDS32131.1 - 0.00037 20.0 0.0 0.019 14.4 0.0 2.2 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 CDS32131.1 - 0.11 12.6 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 PglZ domain AAA_6 PF12774.7 CDS32132.1 - 1.6e-151 503.9 0.0 1.1e-149 497.8 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CDS32132.1 - 4.1e-109 363.9 0.0 1.3e-108 362.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDS32132.1 - 4.7e-100 334.8 0.3 8.4e-98 327.4 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 CDS32132.1 - 1.1e-95 321.1 18.3 9.2e-90 301.6 14.6 4.2 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CDS32132.1 - 2e-85 285.4 0.6 2e-85 285.4 0.6 3.3 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS32132.1 - 6.3e-78 260.4 1.6 1.1e-73 246.6 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS32132.1 - 4e-60 202.4 0.3 8.6e-60 201.3 0.3 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS32132.1 - 1.3e-53 182.3 10.9 2.4e-53 181.4 10.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS32132.1 - 2.2e-47 160.0 0.0 1.4e-42 144.6 0.0 3.4 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CDS32132.1 - 2.1e-30 105.4 0.2 7.7e-30 103.6 0.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDS32132.1 - 5.5e-28 97.7 0.0 3.8e-12 46.4 0.0 6.0 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS32132.1 - 1.1e-19 70.5 0.4 6.5e-19 68.0 0.4 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CDS32132.1 - 1.1e-11 45.3 0.0 0.0019 18.6 0.0 4.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS32132.1 - 8.3e-09 35.8 3.2 0.077 13.3 0.0 5.9 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.6 CDS32132.1 - 1.5e-08 35.2 0.7 0.012 16.0 0.0 4.9 5 0 0 5 5 3 2 AAA ATPase domain AAA_18 PF13238.6 CDS32132.1 - 1.6e-06 28.7 0.0 0.72 10.4 0.0 5.3 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 CDS32132.1 - 7.3e-05 21.9 0.1 0.11 11.5 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 CDS32132.1 - 0.00011 21.9 0.0 0.0029 17.3 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 CDS32132.1 - 0.00025 20.8 0.7 7.7 6.2 0.1 4.2 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 CDS32132.1 - 0.0011 19.1 0.0 0.097 12.8 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_29 PF13555.6 CDS32132.1 - 0.0014 18.3 0.5 12 5.7 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain UPF0242 PF06785.11 CDS32132.1 - 0.0046 17.1 1.8 0.0046 17.1 1.8 4.3 4 1 1 5 5 3 1 Uncharacterised protein family (UPF0242) N-terminus DUF815 PF05673.13 CDS32132.1 - 0.0096 15.1 0.2 5.7 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CDS32132.1 - 0.025 15.1 0.0 69 3.9 0.0 4.5 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.15 CDS32132.1 - 0.041 13.8 0.1 33 4.4 0.0 4.1 5 0 0 5 5 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 CDS32132.1 - 0.11 12.9 0.3 68 3.9 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 CDS32132.1 - 0.14 11.7 0.0 1.3 8.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CDS32132.1 - 0.24 11.1 1.5 28 4.4 0.1 3.2 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 CDS32132.1 - 0.29 11.0 0.0 0.29 11.0 0.0 3.9 6 0 0 6 6 2 0 ATPase domain predominantly from Archaea GcrA PF07750.11 CDS32132.1 - 0.88 10.0 4.7 1.5 9.2 0.7 2.5 2 0 0 2 2 2 0 GcrA cell cycle regulator AAA_19 PF13245.6 CDS32132.1 - 2.1 8.7 5.5 5.7 7.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain MerR-DNA-bind PF09278.11 CDS32132.1 - 5.5 7.6 12.4 17 6.0 5.8 3.3 2 0 0 2 2 2 0 MerR, DNA binding Exonuc_VII_L PF02601.15 CDS32132.1 - 8.1 5.9 27.2 0.031 13.8 0.4 4.2 4 1 0 4 4 4 0 Exonuclease VII, large subunit Sulfate_transp PF00916.20 CDS32133.1 - 1.7e-104 349.6 18.1 2.8e-104 348.9 18.1 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDS32133.1 - 5.1e-19 68.0 0.1 1.1e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain SNF2_N PF00176.23 CDS32134.1 - 5.6e-54 183.2 1.1 1.3e-53 181.9 1.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS32134.1 - 1.7e-13 50.9 0.6 1.1e-11 45.1 0.4 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ADD_ATRX PF17981.1 CDS32134.1 - 2.8e-08 33.5 1.3 9.8e-08 31.8 1.3 2.0 1 0 0 1 1 1 1 Cysteine Rich ADD domain TFIIF_beta_N PF17683.1 CDS32134.1 - 0.0013 19.4 0.4 0.013 16.2 0.1 3.0 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus ERCC3_RAD25_C PF16203.5 CDS32134.1 - 0.091 12.0 0.7 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase K_channel_TID PF07941.11 CDS32134.1 - 0.97 9.9 6.1 3.2 8.3 6.1 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-RING_5 PF14634.6 CDS32134.1 - 1.4 8.9 7.2 4.2 7.4 7.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 CDS32134.1 - 6.6 6.7 18.4 0.07 13.0 10.0 2.1 2 0 0 2 2 2 0 PHD-finger Arm PF00514.23 CDS32135.1 - 1.4e-13 50.4 6.5 0.00065 19.6 0.2 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CDS32135.1 - 2.2e-10 39.9 3.5 0.16 12.3 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 CDS32135.1 - 9.9e-09 35.4 4.3 2.5e-05 24.4 0.3 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 CDS32135.1 - 3e-06 26.0 2.5 5.3e-06 25.2 2.3 1.6 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 CDS32135.1 - 3.4e-06 27.4 2.3 1.2 9.5 0.1 4.3 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CDS32135.1 - 4.8e-05 23.7 2.5 0.54 10.8 0.0 3.9 3 1 0 3 3 3 2 HEAT-like repeat TFIIS_M PF07500.14 CDS32135.1 - 0.025 15.1 0.1 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Prok_Ub PF14454.6 CDS32135.1 - 0.026 14.2 0.1 0.069 12.8 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic Ubiquitin TAF6_C PF07571.13 CDS32135.1 - 0.044 14.1 0.2 9 6.7 0.1 3.2 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Atx10homo_assoc PF09759.9 CDS32135.1 - 0.045 13.8 2.0 0.32 11.1 0.1 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 CDS32135.1 - 0.6 10.2 6.1 10 6.2 0.5 3.4 3 0 0 3 3 3 0 V-ATPase subunit H Rgp1 PF08737.10 CDS32136.1 - 1.3e-10 41.0 1.2 1.2e-09 37.8 1.2 2.4 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 CDS32136.1 - 0.03 14.4 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Tex_N PF09371.10 CDS32136.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain SIL1 PF16782.5 CDS32137.1 - 0.0027 17.0 0.5 0.0037 16.5 0.5 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 PBECR5 PF18814.1 CDS32137.1 - 0.077 12.9 2.3 0.11 12.4 2.3 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 zf-RING_UBOX PF13445.6 CDS32138.1 - 1.8e-09 37.4 6.8 2.3e-08 33.9 2.6 3.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS32138.1 - 1.4e-07 31.2 4.0 1.4e-07 31.2 4.0 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CDS32138.1 - 2e-06 27.8 9.9 2.2e-05 24.5 2.2 4.6 6 0 0 6 6 5 2 B-box zinc finger zf-C3HC4_2 PF13923.6 CDS32138.1 - 7.6e-05 22.5 6.1 7.6e-05 22.5 6.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS32138.1 - 0.00021 21.6 4.8 0.00021 21.6 4.8 4.3 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDS32138.1 - 0.0005 20.2 3.2 0.0005 20.2 3.2 4.4 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDS32138.1 - 0.00063 19.7 3.6 0.00063 19.7 3.6 4.5 5 0 0 5 5 5 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDS32138.1 - 0.0008 19.2 2.8 0.0008 19.2 2.8 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Rpr2 PF04032.16 CDS32138.1 - 2.8 8.3 15.1 0.86 9.9 3.1 4.1 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_11 PF17123.5 CDS32138.1 - 4.4 7.1 7.8 35 4.3 5.1 3.0 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 CDS32138.1 - 5.6 7.2 28.0 60 3.9 9.5 4.8 2 2 0 2 2 2 0 FYVE zinc finger Syntaxin_2 PF14523.6 CDS32138.1 - 9 6.7 8.3 14 6.2 0.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Neur_chan_LBD PF02931.23 CDS32139.1 - 9.5e-55 185.4 2.0 1.5e-54 184.7 2.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS32139.1 - 1.2e-35 123.7 0.0 9.7e-33 114.2 0.0 2.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 CDS32139.1 - 6 6.2 8.9 1.8 7.9 5.9 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF5332 PF17266.2 CDS32147.1 - 0.1 12.3 6.1 1.7 8.3 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5332) Keratin_B2_2 PF13885.6 CDS32147.1 - 8.2 6.5 13.3 3.1 7.8 1.3 2.6 3 0 0 3 3 3 0 Keratin, high sulfur B2 protein Baculo_PEP_C PF04513.12 CDS32149.1 - 0.13 12.3 0.1 11 6.1 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2555 PF10742.9 CDS32153.2 - 0.059 13.2 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) MgtE_N PF03448.17 CDS32153.2 - 0.23 12.1 0.9 11 6.6 0.0 3.7 4 0 0 4 4 4 0 MgtE intracellular N domain P2 PF07194.11 CDS32154.2 - 0.0099 15.9 0.1 5.7 7.1 0.0 3.0 2 0 0 2 2 2 2 P2 response regulator binding domain CRAL_TRIO_N PF03765.15 CDS32154.2 - 0.011 16.0 0.6 10 6.4 0.0 3.2 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain DUF2555 PF10742.9 CDS32154.2 - 0.025 14.4 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) URO-D PF01208.17 CDS32154.2 - 0.049 12.8 0.1 3 6.9 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) DUF2497 PF10691.9 CDS32154.2 - 0.052 14.0 6.3 1.6 9.2 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2497) DUF370 PF04025.12 CDS32154.2 - 0.059 13.5 0.0 5.2 7.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Ribonuc_red_2_N PF08471.10 CDS32154.2 - 0.1 12.8 2.8 2.5 8.4 0.1 3.5 3 0 0 3 3 3 0 Class II vitamin B12-dependent ribonucleotide reductase SseB_C PF14581.6 CDS32154.2 - 0.1 12.7 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF4512 PF14975.6 CDS32156.1 - 2.9 8.7 0.0 2.9 8.7 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4512) F5_F8_type_C PF00754.25 CDS32157.1 - 6.2e-13 49.0 0.0 2.1e-11 44.1 0.0 2.7 2 1 1 3 3 3 1 F5/8 type C domain PDEase_I PF00233.19 CDS32160.1 - 1.9e-77 260.2 1.3 3.8e-77 259.2 1.3 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CDS32160.1 - 3.8e-28 98.8 0.0 1e-12 48.8 0.0 2.8 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CDS32160.1 - 1.2e-10 41.9 0.0 0.00022 21.6 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 CDS32160.1 - 4.3e-05 23.9 0.0 0.84 10.0 0.0 3.4 3 1 0 3 3 3 2 GAF domain F-box PF00646.33 CDS32161.1 - 2.2e-05 24.2 0.2 0.0013 18.6 0.2 3.5 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 CDS32161.1 - 0.00016 21.9 20.5 0.29 11.6 0.3 6.1 3 2 5 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CDS32161.1 - 0.0012 18.7 0.6 0.004 17.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 CDS32161.1 - 0.6 9.9 21.6 0.052 13.3 2.2 5.0 5 3 1 6 6 6 0 Leucine rich repeat LSM14 PF12701.7 CDS32162.1 - 3.3e-18 65.6 0.0 6.7e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CDS32162.1 - 4.3e-07 30.0 0.0 8.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 CDS32162.1 - 0.021 15.7 4.5 0.021 15.7 4.5 3.1 1 1 1 2 2 2 0 FDF domain Kelch_1 PF01344.25 CDS32163.1 - 1.5e-74 245.4 21.7 8.7e-16 57.2 0.8 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CDS32163.1 - 1e-30 105.0 8.9 2.5e-07 30.7 0.1 6.6 3 1 3 6 6 6 6 Kelch motif BTB PF00651.31 CDS32163.1 - 6.4e-30 103.7 0.1 1e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDS32163.1 - 2.3e-25 88.6 0.2 4.7e-25 87.7 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CDS32163.1 - 4.9e-24 83.3 8.8 1.2e-05 25.1 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDS32163.1 - 4.1e-20 71.6 13.4 1.4e-06 28.5 0.4 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS32163.1 - 3e-18 65.6 10.1 0.00096 19.1 0.0 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS32163.1 - 2.7e-06 27.2 9.8 0.05 13.6 0.1 5.4 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 CDS32163.1 - 0.035 14.6 12.7 0.58 10.7 0.1 5.0 5 0 0 5 5 5 0 PQQ-like domain Ribosomal_L34e PF01199.18 CDS32164.1 - 1.3e-39 134.4 7.5 1.3e-39 134.4 7.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L34e YchF-GTPase_C PF06071.13 CDS32165.2 - 1.6e-38 130.7 2.8 1.6e-38 130.7 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CDS32165.2 - 2.6e-22 79.1 0.0 5.6e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS32165.2 - 6.2e-08 32.3 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 CDS32165.2 - 0.032 14.5 0.0 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TGS PF02824.21 CDS32165.2 - 0.047 13.8 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 TGS domain MeaB PF03308.16 CDS32165.2 - 0.055 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 CDS32166.1 - 1.2e-101 340.4 0.8 1.4e-101 340.2 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS32166.1 - 1.1e-15 57.6 0.9 2.2e-12 46.8 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS32166.1 - 6.4e-05 22.4 0.9 0.0046 16.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDS32166.1 - 0.00016 21.9 0.1 0.25 11.6 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDS32166.1 - 0.012 15.1 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 CDS32166.1 - 0.035 13.6 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CDS32166.1 - 0.083 12.7 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDS32166.1 - 0.2 11.6 0.2 5.9 6.8 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase Lectin_C PF00059.21 CDS32167.1 - 1.2e-124 408.8 15.6 9.9e-16 58.4 0.0 11.5 11 1 0 11 11 11 11 Lectin C-type domain UL45 PF05473.12 CDS32167.1 - 1.6e-06 27.9 20.2 4.8 6.8 0.0 9.5 8 1 1 9 9 9 4 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 CDS32167.1 - 0.00017 20.9 12.6 0.36 10.1 0.0 6.4 8 0 0 8 8 8 3 Chordopoxvirus A33R protein Xlink PF00193.17 CDS32167.1 - 0.0015 18.8 4.4 21 5.6 0.1 6.0 6 0 0 6 6 6 1 Extracellular link domain RCR PF12273.8 CDS32167.1 - 0.1 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MFS_1 PF07690.16 CDS32168.1 - 0.015 14.2 1.3 0.019 13.9 1.3 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily fn3 PF00041.21 CDS32171.1 - 1.6e-17 63.6 1.6 0.0021 18.3 0.1 4.2 4 0 0 4 4 4 4 Fibronectin type III domain Tissue_fac PF01108.17 CDS32171.1 - 4.7e-10 39.3 3.8 0.13 12.1 0.1 4.2 4 0 0 4 4 4 4 Tissue factor TOM13 PF08219.11 CDS32171.1 - 0.096 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Outer membrane protein TOM13 DUF4829 PF16111.5 CDS32171.1 - 0.18 12.6 2.2 0.26 12.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4829) 2OG-FeII_Oxy_2 PF13532.6 CDS32174.2 - 4.6e-16 59.6 0.0 6e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ldh_1_C PF02866.18 CDS32175.2 - 2.5e-07 30.8 0.0 5.5e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DUF1871 PF08958.10 CDS32175.2 - 0.076 13.3 0.1 21 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) EF1_GNE PF00736.19 CDS32176.1 - 9.7e-35 118.6 1.7 1.6e-34 117.9 0.3 2.0 2 1 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Stm1_N PF09598.10 CDS32176.1 - 0.0019 19.0 6.0 0.002 18.9 0.4 2.3 2 0 0 2 2 2 1 Stm1 PrlF_antitoxin PF15937.5 CDS32176.1 - 0.028 14.9 0.3 0.15 12.6 0.0 2.3 3 0 0 3 3 3 0 prlF antitoxin for toxin YhaV_toxin AGH PF17558.2 CDS32176.1 - 0.048 13.8 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Androgenic gland hormone NumbF PF06311.12 CDS32176.1 - 0.1 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 NUMB domain DUF4315 PF14193.6 CDS32176.1 - 0.23 11.5 1.5 4.6 7.3 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) BLOC1_2 PF10046.9 CDS32176.1 - 0.37 11.1 3.0 0.65 10.3 0.1 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MIS13 PF08202.11 CDS32176.1 - 1.8 7.8 5.7 0.78 9.0 0.4 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family FlaC_arch PF05377.11 CDS32176.1 - 2.5 8.6 4.5 29 5.1 0.6 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) FERM_M PF00373.18 CDS32177.1 - 1.8e-11 44.5 0.0 4.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 CDS32177.1 - 4.7e-08 33.3 0.1 8.4e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FPP PF05911.11 CDS32177.1 - 0.0087 14.3 0.8 0.013 13.7 0.8 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ubiquitin PF00240.23 CDS32178.1 - 7.6e-63 208.2 2.0 2.6e-33 113.6 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDS32178.1 - 2.9e-32 110.3 1.2 4.4e-17 61.7 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDS32178.1 - 4.4e-10 39.9 1.1 0.00011 22.6 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDS32178.1 - 5.2e-08 33.0 0.3 0.011 15.8 0.0 3.1 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDS32178.1 - 3.1e-07 30.2 0.2 0.0041 17.0 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDS32178.1 - 4.4e-06 27.0 0.2 0.0048 17.2 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS32178.1 - 1.2e-05 25.3 5.1 3.7 7.7 0.1 4.0 3 1 1 4 4 4 3 Ubiquitin-like domain DUF2407 PF10302.9 CDS32178.1 - 3.5e-05 24.3 0.1 0.33 11.5 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CDS32178.1 - 0.0029 17.5 0.0 0.45 10.3 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain FERM_f0 PF16511.5 CDS32178.1 - 0.13 12.6 0.8 20 5.6 0.1 3.1 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM ubiquitin PF00240.23 CDS32179.1 - 1.1e-27 95.6 0.2 1.6e-27 95.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDS32179.1 - 3e-14 52.6 0.3 4.4e-14 52.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDS32179.1 - 7.8e-05 23.1 0.6 0.00037 20.9 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDS32179.1 - 0.003 17.5 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS32179.1 - 0.025 14.6 0.1 7.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDS32179.1 - 0.028 14.5 0.0 0.075 13.1 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDS32180.2 - 6.3e-71 234.1 4.2 1.1e-34 118.0 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CDS32180.2 - 8.5e-35 118.4 4.6 1.2e-16 60.3 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDS32180.2 - 5.6e-14 52.4 0.8 3e-05 24.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDS32180.2 - 1.7e-08 34.3 0.3 0.0065 16.4 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDS32180.2 - 5.4e-08 33.1 0.3 0.013 15.9 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDS32180.2 - 5.9e-08 32.8 0.3 0.019 15.0 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDS32180.2 - 6.6e-06 26.6 0.0 0.19 12.3 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDS32180.2 - 4.3e-05 23.5 6.8 8.9 6.4 0.0 4.0 4 0 0 4 4 4 4 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CDS32180.2 - 0.00029 20.7 0.0 0.66 9.8 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 CDS32180.2 - 0.013 15.9 0.0 11 6.5 0.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2870) RBD PF02196.15 CDS32180.2 - 0.026 14.6 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain FERM_f0 PF16511.5 CDS32180.2 - 0.043 14.1 2.0 31 5.0 0.1 3.7 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM DUF3861 PF12977.7 CDS32180.2 - 0.043 14.0 0.1 11 6.3 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) FlgD_ig PF13860.6 CDS32180.2 - 0.1 12.5 0.5 20 5.1 0.1 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain TmoB PF06234.12 CDS32180.2 - 0.11 12.6 0.3 24 5.1 0.0 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 CDS32180.2 - 0.13 12.4 0.5 1.6 8.9 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase FHA PF00498.26 CDS32181.1 - 2.4e-12 47.0 0.1 7e-12 45.5 0.1 1.8 1 1 1 2 2 2 1 FHA domain PHD PF00628.29 CDS32181.1 - 1.1e-09 38.1 8.5 2.1e-09 37.1 8.5 1.5 1 0 0 1 1 1 1 PHD-finger Yop-YscD_cpl PF16697.5 CDS32181.1 - 0.00015 22.0 0.0 0.031 14.6 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain C1_1 PF00130.22 CDS32181.1 - 0.014 15.3 2.3 0.028 14.3 2.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 CDS32181.1 - 0.021 15.1 3.2 0.041 14.1 3.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-CW PF07496.15 CDS32181.1 - 0.065 13.3 5.9 0.17 11.9 5.9 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger DUF5427 PF10310.9 CDS32181.1 - 0.35 9.8 9.7 0.46 9.4 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Prok-RING_1 PF14446.6 CDS32181.1 - 1.8 8.5 8.3 0.21 11.6 3.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 GOLGA2L5 PF15070.6 CDS32183.1 - 2.8e-07 29.6 50.6 2.3e-05 23.3 20.8 6.0 1 1 6 7 7 7 2 Putative golgin subfamily A member 2-like protein 5 TMF_DNA_bd PF12329.8 CDS32183.1 - 0.0078 16.2 1.5 0.0078 16.2 1.5 13.0 7 3 6 13 13 13 2 TATA element modulatory factor 1 DNA binding TBD PF12845.7 CDS32183.1 - 1.6 8.7 14.5 10 6.1 0.6 4.4 4 0 0 4 4 4 0 TBD domain NapD PF03927.13 CDS32183.1 - 5.8 7.0 7.4 10 6.3 0.1 4.3 4 0 0 4 4 4 0 NapD protein RPN2_C PF18004.1 CDS32184.1 - 5.7e-48 162.9 3.2 5.7e-48 162.9 3.2 3.5 4 0 0 4 4 4 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CDS32184.1 - 7.1e-37 124.0 30.6 5.7e-09 36.0 0.2 8.4 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDS32184.1 - 1.1e-18 67.4 5.9 8.4e-14 51.7 0.2 5.8 4 2 2 6 6 6 1 HEAT repeats HEAT PF02985.22 CDS32184.1 - 0.003 17.7 0.9 2 8.9 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat ANAPC3 PF12895.7 CDS32184.1 - 0.0078 16.4 1.6 0.6 10.4 0.4 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_EZ PF13513.6 CDS32184.1 - 0.0087 16.5 0.8 9.5 6.8 0.1 3.9 3 0 0 3 3 3 1 HEAT-like repeat ERAP1_C PF11838.8 CDS32184.1 - 0.011 15.4 1.4 0.097 12.2 0.0 2.8 3 0 0 3 3 3 0 ERAP1-like C-terminal domain DUF1702 PF08012.11 CDS32184.1 - 0.022 13.7 0.4 0.19 10.6 0.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1702) HEAT_PBS PF03130.16 CDS32184.1 - 0.086 13.6 7.8 3 8.8 1.2 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat TPR_19 PF14559.6 CDS32184.1 - 0.14 12.6 3.0 13 6.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat LRS4 PF10422.9 CDS32185.1 - 0.031 13.9 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PAS_11 PF14598.6 CDS32186.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain TPR_2 PF07719.17 CDS32187.1 - 6.4e-19 66.5 18.0 0.00029 20.7 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32187.1 - 2.5e-18 65.0 23.5 2.1e-06 27.3 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC8 PF04049.13 CDS32187.1 - 6.6e-18 65.1 0.0 1.6e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 CDS32187.1 - 6.5e-17 60.3 8.6 0.0013 18.8 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32187.1 - 1.2e-09 38.3 17.6 0.0017 18.6 1.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32187.1 - 2.2e-09 37.4 9.6 0.0034 18.1 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32187.1 - 1.4e-08 34.8 22.3 0.0016 18.7 0.2 5.9 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDS32187.1 - 2.1e-07 30.5 11.0 0.06 13.4 0.0 6.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32187.1 - 3.1e-07 30.8 2.6 0.6 10.6 0.1 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32187.1 - 1.3e-06 28.4 10.5 4.2 8.0 0.0 8.6 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS32187.1 - 3.2e-06 26.7 9.7 0.0084 15.8 0.0 4.3 3 1 1 4 4 4 2 TPR repeat TPR_15 PF13429.6 CDS32187.1 - 6e-06 25.7 0.7 6e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32187.1 - 1.2e-05 25.4 4.5 2.9 8.1 0.9 5.0 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32187.1 - 0.0001 22.8 10.9 0.46 11.2 0.3 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS32187.1 - 0.0014 19.2 14.3 0.32 11.7 0.1 7.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDS32187.1 - 0.013 15.3 0.3 0.11 12.4 0.0 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat ChAPs PF09295.10 CDS32187.1 - 0.014 14.5 0.0 1 8.3 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4192 PF13830.6 CDS32187.1 - 0.015 15.4 0.2 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TPR_4 PF07721.14 CDS32187.1 - 0.25 12.1 1.8 2.3e+02 2.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 CDS32190.1 - 9.7e-08 32.4 1.1 1.7e-07 31.6 0.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS32190.1 - 2.6e-07 29.7 0.1 0.0048 16.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS32190.1 - 6.8e-06 25.6 0.7 0.01 15.7 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDS32190.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 EF hand PBP PF01161.20 CDS32191.1 - 1.7e-08 34.8 0.0 2.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Band_7 PF01145.25 CDS32192.2 - 3.2e-18 66.4 0.0 6.8e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family SCP2 PF02036.17 CDS32192.2 - 5.2e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family FUN14 PF04930.15 CDS32193.1 - 2.8e-17 62.9 1.7 3.5e-17 62.6 1.7 1.1 1 0 0 1 1 1 1 FUN14 family Circo_capsid PF02443.15 CDS32195.1 - 1.2e-07 31.5 0.1 3e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Circovirus capsid protein Viral_Rep PF02407.16 CDS32195.1 - 1.9e-06 28.0 0.0 3.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Putative viral replication protein RNA_helicase PF00910.22 CDS32196.2 - 2.6e-11 43.8 0.0 7.4e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 RNA helicase Viral_Rep PF02407.16 CDS32196.2 - 1.7e-06 28.2 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Putative viral replication protein DUF325 PF03804.13 CDS32197.1 - 0.16 12.0 0.0 1.5 8.9 0.1 2.3 2 1 1 3 3 3 0 Viral proteins of unknown function Ank_2 PF12796.7 CDS32198.2 - 1.4e-41 141.0 22.3 1.8e-14 54.1 1.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32198.2 - 1.6e-25 89.1 6.8 2.2e-07 31.3 0.3 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32198.2 - 2.6e-23 79.6 9.6 0.0004 20.6 0.2 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 CDS32198.2 - 8.7e-23 79.7 15.5 5.7e-06 26.5 0.6 7.7 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDS32198.2 - 1.4e-22 79.4 4.1 2.8e-07 30.7 0.5 5.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 CDS32198.2 - 0.028 14.8 0.1 1.2 9.5 0.0 2.6 2 1 0 2 2 2 0 Phage T7 capsid assembly protein GTP_EFTU PF00009.27 CDS32200.1 - 2.7e-60 203.2 0.0 4.4e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDS32200.1 - 5.2e-35 119.8 0.0 9.6e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CDS32200.1 - 6.2e-27 93.5 0.0 1.6e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDS32200.1 - 1.3e-17 63.6 0.0 4e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDS32200.1 - 2.1e-11 44.1 0.0 5.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDS32200.1 - 1.1e-06 28.5 0.0 3.8e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain AIG1 PF04548.16 CDS32200.1 - 0.0061 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Enkurin PF13864.6 CDS32200.1 - 0.014 15.8 0.0 1.1 9.8 0.0 2.6 3 0 0 3 3 3 0 Calmodulin-binding MMR_HSR1 PF01926.23 CDS32200.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 CDS32200.1 - 0.044 14.3 0.0 8.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Metallophos PF00149.28 CDS32201.1 - 5e-36 125.1 0.0 6.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDS32201.1 - 1.1e-11 45.0 0.0 3.1e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Na_H_Exchanger PF00999.21 CDS32202.1 - 2.6e-62 210.8 45.8 3.5e-62 210.4 45.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 CDS32204.1 - 4.2e-57 193.7 51.4 5.3e-57 193.3 51.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family COX8 PF02285.15 CDS32204.1 - 0.37 10.7 2.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII SCF PF02404.15 CDS32204.1 - 7.7 5.8 6.2 1.2 8.4 0.2 2.5 3 0 0 3 3 3 0 Stem cell factor PDZ_6 PF17820.1 CDS32206.1 - 1.4e-06 28.0 0.1 4.6e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS32206.1 - 0.028 14.7 0.1 3.3 8.1 0.0 2.7 1 1 1 2 2 2 0 PDZ domain PDZ PF00595.24 CDS32206.1 - 0.043 14.2 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Proteasome PF00227.26 CDS32208.1 - 8.1e-49 165.7 0.1 1e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CDS32208.1 - 0.00057 19.2 1.4 0.00057 19.2 1.4 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal GFO_IDH_MocA PF01408.22 CDS32209.1 - 1.3e-15 58.2 0.0 2.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CDS32209.1 - 3.2e-08 33.6 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Cyclin_N PF00134.23 CDS32210.1 - 1.5e-09 37.7 1.5 0.00059 19.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS32210.1 - 0.053 13.6 0.8 0.24 11.5 0.1 2.2 2 1 0 2 2 2 0 Cyclin, C-terminal domain HIT PF01230.23 CDS32210.1 - 0.069 13.9 0.1 0.21 12.4 0.1 1.8 2 0 0 2 2 2 0 HIT domain FAR1 PF03101.15 CDS32211.1 - 0.027 15.1 1.4 0.032 14.9 0.3 1.7 2 0 0 2 2 2 0 FAR1 DNA-binding domain FLYWCH PF04500.16 CDS32211.1 - 0.081 13.1 1.4 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 FLYWCH zinc finger domain Rep_fac-A_3 PF08661.11 CDS32212.1 - 0.11 12.9 0.1 4.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Replication factor A protein 3 UCH PF00443.29 CDS32213.1 - 1.8e-42 145.6 0.3 7.9e-42 143.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS32213.1 - 2e-27 96.6 0.2 6e-27 95.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 CDS32213.1 - 0.14 12.2 0.7 0.63 10.1 0.7 2.2 1 0 0 1 1 1 0 Double zinc ribbon ANAPC4_WD40 PF12894.7 CDS32214.1 - 0.0062 16.8 0.0 8 6.8 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS32214.1 - 0.043 14.7 0.6 51 5.0 0.0 3.9 3 1 0 3 3 3 0 WD domain, G-beta repeat C2 PF00168.30 CDS32215.1 - 1.7e-15 57.1 0.1 2e-15 57.0 0.1 1.0 1 0 0 1 1 1 1 C2 domain DUF4704 PF15787.5 CDS32218.2 - 9.8e-07 28.3 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) RCC1 PF00415.18 CDS32218.2 - 0.026 15.2 0.3 17 6.1 0.0 3.0 2 2 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat T4_Gp59_N PF08993.10 CDS32218.2 - 0.14 12.6 0.0 24 5.4 0.0 2.3 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase DUF3980 PF13140.6 CDS32218.2 - 0.14 12.6 0.0 1.4 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Tenui_PVC2 PF06656.11 CDS32218.2 - 0.32 8.8 3.5 0.83 7.5 0.1 2.3 3 0 0 3 3 3 0 Tenuivirus PVC2 protein GF_recep_IV PF14843.6 CDS32219.2 - 0.0013 18.5 52.2 0.0076 16.1 24.6 3.8 2 1 0 3 3 3 2 Growth factor receptor domain IV DUF4215 PF13948.6 CDS32219.2 - 0.037 14.5 0.8 0.037 14.5 0.8 7.4 6 2 2 8 8 8 0 Domain of unknown function (DUF4215) Coat_F PF07875.12 CDS32221.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Coat F domain MS_channel PF00924.18 CDS32221.1 - 0.048 13.2 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel pPIWI_RE_X PF13111.6 CDS32221.1 - 0.063 12.5 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain Tenui_PVC2 PF06656.11 CDS32223.1 - 0.18 9.6 0.9 1.5 6.6 0.1 2.0 2 0 0 2 2 2 0 Tenuivirus PVC2 protein Parvo_NS1 PF01057.17 CDS32224.1 - 1.5e-09 37.4 0.1 1.7e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS32224.1 - 0.0078 15.1 0.0 0.0084 15.0 0.0 1.0 1 0 0 1 1 1 1 Papillomavirus helicase RNA_helicase PF00910.22 CDS32224.1 - 0.037 14.4 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA helicase 7tm_1 PF00001.21 CDS32225.1 - 8.4e-13 48.2 12.3 2.2e-12 46.9 12.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS32225.1 - 2.9e-12 46.5 8.2 2.9e-12 46.5 8.2 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw UPA PF17217.3 CDS32225.1 - 0.0022 17.9 0.1 0.007 16.3 0.0 1.9 2 0 0 2 2 2 1 UPA domain 7TM_GPCR_Srx PF10328.9 CDS32225.1 - 0.0063 16.2 13.3 0.0097 15.6 10.7 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx WD40 PF00400.32 CDS32226.1 - 2.8e-08 34.3 0.5 5.4e-05 23.9 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Carn_acyltransf PF00755.20 CDS32227.1 - 2.2e-85 287.5 0.0 2.7e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HEPN_STY4199 PF18729.1 CDS32227.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 STY4199-like HEPN NIF PF03031.18 CDS32228.2 - 1.8e-55 187.0 0.6 1.8e-55 187.0 0.6 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase CBFB_NFYA PF02045.15 CDS32229.2 - 4.2e-25 88.1 9.5 1.4e-24 86.5 9.5 1.9 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B FAM219A PF15260.6 CDS32229.2 - 1.6 9.1 6.6 0.16 12.3 0.4 2.4 2 1 1 3 3 3 0 Protein family FAM219A TERB2 PF15101.6 CDS32229.2 - 4.5 7.3 9.1 30 4.6 0.1 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF1827 PF08860.10 CDS32230.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) PID PF00640.23 CDS32231.1 - 2.7e-23 82.6 0.0 3.8e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.24 CDS32231.1 - 1.1e-15 57.4 0.0 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 SH2 domain PilO PF04350.13 CDS32232.1 - 0.15 12.2 0.0 0.94 9.6 0.0 2.0 2 0 0 2 2 2 0 Pilus assembly protein, PilO OGG_N PF07934.12 CDS32233.1 - 5e-21 75.0 0.2 8.6e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CDS32233.1 - 9.3e-09 35.7 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDS32233.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SRR1 PF07985.12 CDS32234.1 - 3.4e-08 33.4 0.0 6.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 SRR1 CTP_transf_like PF01467.26 CDS32235.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase-like Miga PF10265.9 CDS32235.1 - 9.6 5.0 10.6 12 4.7 10.6 1.3 1 0 0 1 1 1 0 Mitoguardin CTP_transf_like PF01467.26 CDS32236.1 - 2.5e-12 47.2 0.0 6.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like SMC_N PF02463.19 CDS32238.1 - 1.8e-52 178.0 54.6 2.4e-51 174.3 54.6 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDS32238.1 - 1.1e-24 87.0 0.0 3.4e-24 85.4 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CDS32238.1 - 4e-15 56.9 26.5 4e-15 56.9 26.5 6.8 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 CDS32238.1 - 1e-13 51.8 11.3 6.4e-07 29.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDS32238.1 - 2e-10 41.0 18.9 2e-10 41.0 18.9 4.4 2 2 1 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 CDS32238.1 - 0.00068 20.2 13.1 0.00068 20.2 13.1 8.1 4 2 4 8 8 8 2 Apg6 coiled-coil region AAA_29 PF13555.6 CDS32238.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CDS32238.1 - 0.14 11.5 0.0 0.14 11.5 0.0 4.2 4 2 1 6 6 6 0 FtsK/SpoIIIE family XPG_I_2 PF12813.7 CDS32239.1 - 0.0004 19.9 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 CDS32239.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 XPG I-region XPG_N PF00752.17 CDS32239.1 - 0.054 14.0 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain PB1 PF00564.24 CDS32241.1 - 3e-11 43.1 0.3 4.7e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 CDS32241.1 - 1.7e-09 37.9 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS32241.1 - 5.8e-07 29.3 0.1 2.1e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain HAD PF12710.7 CDS32242.1 - 9.1e-08 32.7 0.0 1.1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDS32242.1 - 2.7e-07 31.1 0.0 3.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CDS32242.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF3149 PF11346.8 CDS32243.1 - 0.042 13.5 1.2 0.069 12.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Rax2 PF12768.7 CDS32243.1 - 0.064 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EVI2A PF05399.11 CDS32243.1 - 0.41 10.2 2.8 0.67 9.5 2.8 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Hydrolase PF00702.26 CDS32244.1 - 1.6e-14 54.7 0.0 3.1e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CDS32244.1 - 3.6e-08 33.2 0.1 4.8e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CDS32244.1 - 7e-08 33.1 0.0 1.3e-07 32.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CDS32244.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase DUF4518 PF15008.6 CDS32244.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Nkap_C PF06047.11 CDS32245.1 - 8.1e-48 160.7 2.5 8.1e-48 160.7 2.5 2.5 3 0 0 3 3 3 1 NF-kappa-B-activating protein C-terminal domain DUF4603 PF15376.6 CDS32245.1 - 3.4e-05 21.5 15.7 4.3e-05 21.2 15.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Macoilin PF09726.9 CDS32245.1 - 0.015 13.9 19.7 0.019 13.5 19.7 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CDS32245.1 - 0.44 9.2 8.1 0.54 8.9 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.17 CDS32245.1 - 1.6 8.8 13.0 0.055 13.6 6.6 1.9 2 0 0 2 2 2 0 DDHD domain Zip PF02535.22 CDS32245.1 - 6.1 6.0 15.2 10 5.2 15.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3883 PF13020.6 CDS32246.1 - 0.0019 18.2 0.0 0.008 16.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 CDS32246.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Snf7 PF03357.21 CDS32248.1 - 2e-39 135.0 6.4 2.4e-39 134.7 6.4 1.1 1 0 0 1 1 1 1 Snf7 Sugarporin_N PF11471.8 CDS32248.1 - 0.0045 16.9 1.2 0.0085 16.0 1.2 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Prefoldin_2 PF01920.20 CDS32248.1 - 0.013 15.4 9.9 0.021 14.8 0.3 2.8 2 1 1 3 3 3 0 Prefoldin subunit Cluap1 PF10234.9 CDS32248.1 - 0.018 14.4 4.4 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 CC2-LZ PF16516.5 CDS32248.1 - 0.62 10.4 9.5 0.18 12.2 3.6 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Suppressor_APC PF11414.8 CDS32248.1 - 0.84 9.7 4.7 0.51 10.4 1.8 2.3 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF1664 PF07889.12 CDS32248.1 - 0.96 9.5 8.7 1.5 8.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 CDS32248.1 - 1.8 8.7 7.1 12 6.1 6.7 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 CDS32249.1 - 0.022 14.9 2.5 0.029 14.5 2.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor Arm-DNA-bind_2 PF12167.8 CDS32249.1 - 0.027 14.4 0.1 0.082 12.8 0.1 1.7 1 1 0 1 1 1 0 Arm DNA-binding domain PAF-AH_p_II PF03403.13 CDS32249.1 - 0.19 10.2 0.0 0.22 10.0 0.0 1.0 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_M1 PF01433.20 CDS32250.1 - 1.9e-81 272.8 2.4 3.2e-81 272.0 2.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CDS32250.1 - 3.3e-49 168.1 0.2 1.3e-48 166.2 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CDS32250.1 - 4e-42 144.5 0.1 9.4e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Complex1_LYR PF05347.15 CDS32250.1 - 1.5e-05 24.9 0.4 5.3e-05 23.2 0.4 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Aminopep PF10023.9 CDS32250.1 - 0.0044 16.4 0.1 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Putative aminopeptidase Thoc2 PF11732.8 CDS32250.1 - 0.14 12.3 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Transcription- and export-related complex subunit Complex1_LYR_2 PF13233.6 CDS32250.1 - 3.4 8.5 6.9 0.76 10.6 1.0 2.8 3 0 0 3 3 3 0 Complex1_LYR-like DHHA2 PF02833.14 CDS32251.1 - 4.9e-27 94.9 0.0 1.2e-26 93.6 0.0 1.7 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CDS32251.1 - 1.9e-10 40.9 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DHH family TUDOR PF00567.24 CDS32252.1 - 0.0053 16.8 0.7 0.016 15.2 0.3 1.8 2 0 0 2 2 2 1 Tudor domain RGP PF03214.13 CDS32252.1 - 0.022 13.9 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide SMN PF06003.12 CDS32252.1 - 2.7 7.2 7.1 17 4.6 0.0 2.7 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) SH3_1 PF00018.28 CDS32254.1 - 3e-14 52.3 0.1 6.8e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS32254.1 - 5.6e-10 38.9 0.2 1e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 CDS32254.1 - 2.5e-09 37.1 9.5 4e-09 36.5 9.5 1.3 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 CDS32254.1 - 8.6e-09 35.0 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 CDS32254.1 - 4.8e-07 29.2 10.9 7.1e-07 28.6 10.9 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Filament PF00038.21 CDS32254.1 - 0.17 11.4 10.7 0.039 13.5 6.3 2.1 2 1 1 3 3 3 0 Intermediate filament protein DUF4398 PF14346.6 CDS32254.1 - 0.26 11.9 2.4 0.49 11.1 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) TetR_C_8 PF14278.6 CDS32254.1 - 1.9 8.6 6.5 3 8.0 0.2 3.1 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region DUF4407 PF14362.6 CDS32254.1 - 7 5.9 11.2 3.7 6.8 9.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nup35_RRM PF05172.13 CDS32255.2 - 7.9e-21 73.9 0.1 2.4e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CDS32255.2 - 1.9e-11 43.8 0.1 3.6e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RhoGEF PF00621.20 CDS32255.2 - 4.6e-11 43.3 7.5 8.6e-11 42.4 7.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CDS32255.2 - 0.047 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 PH domain DUF5365 PF17326.2 CDS32255.2 - 0.099 13.1 0.6 0.32 11.4 0.6 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5365) TMF_TATA_bd PF12325.8 CDS32255.2 - 4.4 7.6 13.4 0.045 14.0 4.4 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 CDS32257.1 - 1.3e-06 29.0 0.5 1.5 9.8 0.2 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32257.1 - 7.9e-05 22.9 0.0 3.5 8.0 0.0 4.9 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans_2 PF07885.16 CDS32258.1 - 3e-32 110.4 18.1 1.2e-16 60.4 0.5 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDS32258.1 - 2.9e-06 26.7 4.4 0.033 13.4 0.0 2.3 2 0 0 2 2 2 2 Ion transport protein SelR PF01641.18 CDS32259.1 - 4.9e-51 171.9 0.1 5.9e-51 171.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CDS32259.1 - 0.00012 21.7 3.8 0.011 15.4 0.1 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein HECT_2 PF09814.9 CDS32259.1 - 0.011 14.7 0.9 0.081 11.8 0.0 1.9 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 CDS32259.1 - 0.41 10.9 3.4 1 9.6 3.4 1.7 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Vinculin PF01044.19 CDS32260.2 - 1.7e-220 734.9 29.1 1e-128 431.2 18.2 2.0 1 1 1 2 2 2 2 Vinculin family Band_3_cyto PF07565.13 CDS32260.2 - 0.00042 20.2 1.7 0.03 14.1 0.0 2.8 3 0 0 3 3 3 1 Band 3 cytoplasmic domain Nbl1_Borealin_N PF10444.9 CDS32260.2 - 0.059 13.0 0.8 24 4.7 0.1 3.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal MerR_2 PF13591.6 CDS32260.2 - 0.12 12.3 0.4 25 4.8 0.1 2.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein Interferon PF00143.19 CDS32260.2 - 0.81 9.9 6.5 13 5.9 0.7 2.8 2 0 0 2 2 2 0 Interferon alpha/beta domain OSCP PF00213.18 CDS32260.2 - 1.2 9.2 10.8 4.5 7.4 0.6 3.0 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit SVIP PF15811.5 CDS32260.2 - 2.9 8.4 6.0 39 4.8 0.6 3.0 2 0 0 2 2 2 0 Small VCP/p97-interacting protein GldM_N PF12081.8 CDS32260.2 - 4 7.5 5.5 28 4.7 0.0 4.2 5 0 0 5 5 5 0 GldM N-terminal domain RB_A PF01858.17 CDS32260.2 - 4.5 7.0 5.8 39 4.0 0.2 3.3 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain GTP_EFTU PF00009.27 CDS32261.1 - 4e-33 114.6 0.0 4e-33 114.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDS32261.1 - 4.1e-17 62.2 0.7 1.5e-16 60.4 0.7 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 CDS32261.1 - 8.5e-14 51.2 0.1 2.7e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CDS32261.1 - 6.7e-10 39.2 3.8 1.2e-06 28.8 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDS32261.1 - 2e-07 31.1 0.0 7.5e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDS32261.1 - 0.00036 20.4 0.1 0.0028 17.5 0.1 2.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDS32261.1 - 0.019 14.9 0.2 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CDS32261.1 - 0.057 13.6 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CDS32261.1 - 0.1 12.9 1.0 1 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain MIase PF02426.16 CDS32261.1 - 0.42 10.8 2.6 4.2 7.6 2.7 2.7 2 0 0 2 2 2 0 Muconolactone delta-isomerase Rap_GAP PF02145.15 CDS32262.1 - 1.1e-37 129.5 0.0 2e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Frag1 PF10277.9 CDS32262.1 - 8.4e-18 64.7 20.0 8.4e-18 64.7 20.0 2.4 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family 2OG-FeII_Oxy_2 PF13532.6 CDS32263.1 - 5.7e-09 36.4 0.0 9.8e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDS32263.1 - 0.098 13.2 0.4 0.26 11.8 0.2 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF543 PF04418.12 CDS32265.1 - 1.4e-20 73.1 0.1 1.5e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Methyltrn_RNA_4 PF09936.9 CDS32265.1 - 0.18 11.6 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Bin3 PF06859.12 CDS32266.1 - 3.2e-32 111.4 0.0 5.5e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 CDS32266.1 - 1.5e-11 44.8 0.0 2.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS32266.1 - 1.3e-09 38.0 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS32266.1 - 4.9e-09 36.2 0.0 8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS32266.1 - 4.1e-07 30.7 0.0 1.4e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS32266.1 - 1.8e-06 28.5 0.0 3.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS32266.1 - 0.0049 16.4 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CDS32266.1 - 0.034 13.5 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 CDS32266.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MMADHC PF10229.9 CDS32267.1 - 1.5e-33 116.7 0.0 2.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein YhhN PF07947.14 CDS32267.1 - 1.6e-21 76.7 14.0 2.3e-21 76.2 14.0 1.1 1 0 0 1 1 1 1 YhhN family Cnd1 PF12717.7 CDS32268.1 - 0.011 15.7 4.9 5.2 7.1 0.1 4.2 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDS32268.1 - 0.021 15.0 0.0 15 6.2 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat KH_1 PF00013.29 CDS32270.1 - 1.5e-27 95.2 1.7 1e-12 47.7 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDS32270.1 - 4.5e-10 39.2 1.2 3e-06 27.0 0.3 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDS32270.1 - 0.00012 21.9 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDS32270.1 - 0.0012 18.9 0.9 1.2 9.3 0.1 2.5 2 0 0 2 2 2 2 NusA-like KH domain Mg_trans_NIPA PF05653.14 CDS32271.1 - 8.4e-105 350.1 19.0 1e-104 349.8 19.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDS32271.1 - 5.4e-06 26.6 3.6 5.4e-06 26.6 3.6 3.6 2 2 1 3 3 3 2 EamA-like transporter family Ig_3 PF13927.6 CDS32272.1 - 4e-16 59.4 3.9 0.00051 20.6 0.3 5.1 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS32272.1 - 4.2e-12 46.0 0.0 0.0017 18.4 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 CDS32272.1 - 9.9e-12 44.9 2.9 0.00015 21.9 0.4 5.4 4 2 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 CDS32272.1 - 2e-09 37.7 0.3 0.0097 16.2 0.0 4.8 5 0 0 5 5 5 2 Immunoglobulin domain V-set PF07686.17 CDS32272.1 - 9.3e-09 35.4 0.2 0.014 15.5 0.0 4.5 4 1 0 4 4 4 2 Immunoglobulin V-set domain DUF4448 PF14610.6 CDS32272.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Izumo-Ig PF16706.5 CDS32272.1 - 0.00011 22.2 0.1 0.08 13.0 0.0 3.5 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CDS32272.1 - 0.0094 16.2 0.0 1 9.7 0.0 3.1 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain EF-hand_7 PF13499.6 CDS32273.1 - 9.5e-09 35.6 1.8 2.2e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS32273.1 - 5.6e-08 32.1 3.6 0.0025 17.6 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDS32273.1 - 3.9e-06 26.0 3.2 0.031 13.8 0.6 3.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CDS32273.1 - 4.5e-05 23.7 0.0 7.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 CDS32273.1 - 0.12 12.4 2.9 6.7 6.7 0.1 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DEAD PF00270.29 CDS32274.1 - 5.8e-35 120.6 0.0 1.1e-34 119.7 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS32274.1 - 1.6e-26 92.9 0.2 1.9e-25 89.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS32274.1 - 2.1e-09 37.6 0.0 5.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDS32274.1 - 0.0038 17.5 0.1 0.043 14.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 CDS32274.1 - 0.007 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PIG-X PF08320.12 CDS32275.1 - 1.1e-12 48.3 0.0 2.1e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 PIG-X / PBN1 Ku PF02735.16 CDS32276.1 - 5.4e-41 140.5 0.0 9.1e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CDS32276.1 - 3.4e-27 95.6 0.1 6.3e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CDS32276.1 - 5e-14 52.8 0.8 9.9e-14 51.8 0.2 1.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Peptidase_S9 PF00326.21 CDS32277.1 - 3.6e-28 98.5 0.0 1.8e-16 60.3 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CDS32277.1 - 6.6e-08 32.5 0.2 3.6e-06 26.8 0.2 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS32277.1 - 1.9e-06 27.3 0.0 0.00015 21.2 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 CDS32277.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 CDS32277.1 - 0.029 15.0 0.1 0.053 14.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 CDS32277.1 - 0.036 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Esterase PF00756.20 CDS32277.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase bZIP_2 PF07716.15 CDS32278.1 - 1.1e-09 38.2 16.0 1.8e-09 37.6 16.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS32278.1 - 6.8e-09 35.7 12.9 1.3e-08 34.8 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor HAUS6_N PF14661.6 CDS32278.1 - 0.016 14.8 0.4 0.019 14.6 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Selenoprotein_S PF06936.11 CDS32278.1 - 0.095 12.5 2.4 0.12 12.2 2.4 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Jagunal PF07086.12 CDS32279.1 - 3.5e-67 226.1 1.2 3.9e-67 225.9 1.2 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis FIBP PF05427.11 CDS32280.1 - 1e-64 219.1 0.2 9.3e-46 156.8 0.0 2.0 1 1 1 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) Sigma70_r4_2 PF08281.12 CDS32280.1 - 0.09 12.5 0.0 19 5.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, region 4 ADK PF00406.22 CDS32281.1 - 4.2e-51 173.0 0.1 5.7e-51 172.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDS32281.1 - 2.6e-32 112.1 0.0 3.6e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS32281.1 - 4e-09 37.1 0.0 6.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS32281.1 - 3.9e-08 33.6 0.0 1.4e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CDS32281.1 - 1.7e-06 27.8 0.4 0.023 14.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.6 CDS32281.1 - 0.002 18.5 0.6 0.0049 17.2 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CDS32281.1 - 0.0044 17.5 0.6 0.015 15.7 0.6 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CDS32281.1 - 0.007 15.7 0.0 0.0092 15.3 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 CDS32281.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 CDS32281.1 - 0.03 14.2 0.9 0.56 10.1 0.1 2.3 1 1 0 2 2 2 0 NTPase AAA_22 PF13401.6 CDS32281.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 CDS32283.1 - 5.3e-21 74.5 0.3 1.5e-20 73.1 0.3 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS32283.1 - 7.1e-14 51.9 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDS32283.1 - 4.1e-13 49.5 0.1 4.3e-12 46.3 0.1 2.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 CDS32283.1 - 0.0098 15.7 0.1 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 CDS32283.1 - 0.022 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain EF1G PF00647.19 CDS32284.1 - 2e-38 130.7 0.1 4.4e-38 129.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CDS32284.1 - 1.6e-11 44.2 0.1 1.6e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDS32284.1 - 2.3e-11 43.7 0.6 2.5e-10 40.4 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDS32284.1 - 5.6e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS32284.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CDS32284.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M16 PF00675.20 CDS32285.1 - 2.4e-52 176.9 0.1 1.7e-51 174.2 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDS32285.1 - 3.4e-30 105.4 0.0 6.2e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Fe_hyd_lg_C PF02906.14 CDS32286.1 - 2.5e-39 135.4 0.0 1.2e-38 133.2 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Snurportin1 PF11538.8 CDS32287.1 - 0.0085 16.3 0.4 0.0085 16.3 0.4 2.4 2 0 0 2 2 2 1 Snurportin1 IQ PF00612.27 CDS32287.1 - 0.027 14.3 0.4 0.027 14.3 0.4 2.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif VPS38 PF17649.1 CDS32287.1 - 0.048 12.5 15.5 0.022 13.6 8.5 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 38 Macoilin PF09726.9 CDS32287.1 - 0.071 11.7 20.7 0.084 11.4 20.7 1.0 1 0 0 1 1 1 0 Macoilin family DS PF01916.17 CDS32287.1 - 0.088 12.0 2.1 0.097 11.9 2.1 1.1 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF848 PF05852.11 CDS32287.1 - 0.19 11.9 12.8 0.1 12.7 10.2 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HAUS6_N PF14661.6 CDS32287.1 - 0.72 9.4 17.0 1.2 8.6 16.2 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Sec20 PF03908.13 CDS32287.1 - 1.1 9.2 5.9 2.9 7.9 5.0 2.1 1 1 0 1 1 1 0 Sec20 TMPIT PF07851.13 CDS32287.1 - 4.7 6.4 12.4 0.86 8.8 8.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 CDS32287.1 - 5.3 7.6 22.7 45 4.6 22.7 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region TRAP-gamma PF07074.12 CDS32288.1 - 9.3e-70 233.6 4.3 1.1e-69 233.4 4.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3043 PF11241.8 CDS32288.1 - 0.044 13.8 0.1 0.072 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) TMEM132D_C PF15706.5 CDS32288.1 - 0.063 13.1 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM208_SND2 PF05620.11 CDS32288.1 - 3.3 7.5 6.5 0.37 10.6 1.6 1.9 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 AAA PF00004.29 CDS32289.1 - 2.8e-40 137.8 0.0 5.5e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS32289.1 - 2e-14 53.1 0.6 1.7e-13 50.2 0.3 2.5 1 1 1 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 CDS32289.1 - 1.2e-09 38.0 0.0 3.7e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CDS32289.1 - 1.8e-05 24.6 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDS32289.1 - 2.9e-05 24.3 0.0 5.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDS32289.1 - 0.00021 21.5 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDS32289.1 - 0.00021 21.3 0.1 0.0023 18.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CDS32289.1 - 0.00075 18.8 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CDS32289.1 - 0.0032 17.9 0.0 0.0066 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CDS32289.1 - 0.0043 16.5 0.1 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDS32289.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDS32289.1 - 0.018 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CDS32289.1 - 0.02 15.2 1.6 0.16 12.3 0.3 2.7 2 1 1 3 3 3 0 AAA domain TsaE PF02367.17 CDS32289.1 - 0.022 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDS32289.1 - 0.031 13.7 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 CDS32289.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDS32289.1 - 0.036 14.6 1.0 0.15 12.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CDS32289.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CDS32289.1 - 0.068 12.5 0.1 1.2 8.4 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 CDS32289.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS32289.1 - 0.099 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDS32289.1 - 0.15 12.5 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDS32289.1 - 0.17 11.6 0.0 0.88 9.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDS32289.1 - 0.19 11.6 0.0 0.88 9.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.21 CDS32291.1 - 3.7e-21 75.6 0.0 1.2e-13 50.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HTH_20 PF12840.7 CDS32291.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain GST_C_2 PF13410.6 CDS32292.1 - 9.4e-07 28.8 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_7 PF13499.6 CDS32293.1 - 4e-13 49.6 3.4 1.4e-05 25.5 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS32293.1 - 2.9e-12 45.4 6.2 2.4e-07 30.1 0.7 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDS32293.1 - 1.4e-10 40.0 14.6 5.5e-07 28.7 1.2 4.3 5 0 0 5 5 5 2 EF hand UPF0154 PF03672.13 CDS32293.1 - 2.7e-05 24.1 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.6 CDS32293.1 - 0.00024 20.5 1.3 0.00024 20.5 1.3 2.9 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CDS32293.1 - 0.0032 17.7 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 CDS32293.1 - 0.012 15.5 0.1 5.4 6.9 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain YqzE PF14038.6 CDS32293.1 - 0.053 13.5 6.1 0.62 10.1 2.4 2.4 2 0 0 2 2 2 0 YqzE-like protein EF-hand_8 PF13833.6 CDS32293.1 - 0.068 13.0 5.6 0.77 9.7 0.4 4.0 3 1 1 4 4 4 0 EF-hand domain pair Caleosin PF05042.13 CDS32293.1 - 0.11 12.5 0.1 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein DDE_Tnp_IS66_C PF13817.6 CDS32293.1 - 0.13 12.5 0.1 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 IS66 C-terminal element RasGEF PF00617.19 CDS32295.1 - 4.1e-27 95.5 0.0 1.2e-26 94.0 0.0 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDS32295.1 - 5e-19 68.5 0.8 1.1e-18 67.3 0.8 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 CDS32295.1 - 0.032 14.7 0.0 1.7 9.2 0.0 2.8 2 0 0 2 2 2 0 PH domain JHD PF17811.1 CDS32296.2 - 1.8e-17 63.7 0.1 3.9e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 CDS32296.2 - 0.0011 19.3 0.0 0.0036 17.7 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDS32296.2 - 0.0048 16.6 0.4 0.0094 15.7 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 CDS32296.2 - 0.051 13.0 0.1 0.087 12.3 0.1 1.5 1 1 0 1 1 1 0 Cupin superfamily protein 7tm_1 PF00001.21 CDS32297.1 - 2.1e-44 151.8 21.2 2.1e-44 151.8 21.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS32297.1 - 7.2e-15 55.1 20.5 1e-14 54.6 20.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.9 CDS32297.1 - 2.4e-05 23.8 22.6 0.00036 19.9 22.6 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF2116 PF09889.9 CDS32297.1 - 2.3 8.3 6.2 9.9 6.2 0.3 3.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4612 PF15389.6 CDS32298.1 - 0.015 16.3 1.5 0.036 15.1 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4612) Yippee-Mis18 PF03226.14 CDS32299.1 - 1.4e-12 47.8 0.1 1.9e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 CDS32299.1 - 0.0071 16.4 0.4 0.016 15.3 0.4 1.5 1 1 0 1 1 1 1 SelR domain DUF4892 PF16234.5 CDS32300.1 - 0.015 14.7 0.5 0.017 14.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) LIM PF00412.22 CDS32301.1 - 1.5e-23 82.8 17.2 1.9e-12 47.2 5.4 2.1 2 0 0 2 2 2 2 LIM domain DUF1272 PF06906.11 CDS32301.1 - 0.82 9.8 17.8 0.097 12.8 2.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) SH3_11 PF18103.1 CDS32302.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain LIM PF00412.22 CDS32303.1 - 1.4e-22 79.7 20.4 1.9e-11 44.0 8.8 2.0 2 0 0 2 2 2 2 LIM domain zf-RING_14 PF17978.1 CDS32303.1 - 0.09 13.2 11.0 0.47 10.9 1.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prot_inhib_II PF02428.15 CDS32303.1 - 0.82 10.2 21.0 1.2 9.6 7.1 2.7 1 1 2 3 3 3 0 Potato type II proteinase inhibitor family PolC_DP2 PF03833.13 CDS32303.1 - 4 5.2 8.2 4.2 5.1 8.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 LIM PF00412.22 CDS32304.1 - 2.5e-26 91.7 26.8 2e-14 53.5 9.6 2.1 2 0 0 2 2 2 2 LIM domain DUF3268 PF11672.8 CDS32304.1 - 0.003 17.9 0.8 0.003 17.9 0.8 2.2 2 0 0 2 2 2 1 zinc-finger-containing domain zinc_ribbon_2 PF13240.6 CDS32304.1 - 0.0052 16.5 3.9 0.097 12.4 0.3 5.3 5 0 0 5 5 5 2 zinc-ribbon domain zf_UBZ PF18439.1 CDS32304.1 - 0.12 12.0 25.8 0.33 10.6 1.4 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger c-SKI_SMAD_bind PF08782.10 CDS32304.1 - 0.55 10.5 16.9 0.94 9.8 3.2 2.8 1 1 2 3 3 3 0 c-SKI Smad4 binding domain DUF2039 PF10217.9 CDS32304.1 - 1.1 9.6 21.1 0.043 14.2 7.1 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-dskA_traR PF01258.17 CDS32304.1 - 1.6 8.7 22.7 1.6 8.7 0.1 4.8 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger Mito_carr PF00153.27 CDS32305.1 - 8.5e-46 153.8 5.8 5.5e-18 64.7 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ion_trans PF00520.31 CDS32307.2 - 1.7e-139 463.0 38.7 6.3e-62 209.0 15.2 3.1 3 0 0 3 3 3 3 Ion transport protein GPHH PF16905.5 CDS32307.2 - 2.6e-31 107.2 0.2 5.1e-31 106.2 0.2 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 CDS32307.2 - 6.6e-28 96.7 0.1 1.4e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 CDS32307.2 - 1.4e-07 30.6 39.7 0.014 14.1 2.3 7.1 6 1 1 7 7 7 7 Polycystin cation channel Glutaredoxin PF00462.24 CDS32310.2 - 7.2e-16 58.2 0.1 1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CDS32310.2 - 2.6e-05 24.6 0.2 3.5e-05 24.1 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 CDS32310.2 - 0.0001 22.3 0.0 0.00035 20.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 CDS32310.2 - 0.0015 18.9 0.1 0.0023 18.4 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 CDS32310.2 - 0.0069 16.2 0.2 0.048 13.4 0.1 1.9 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin PF00085.20 CDS32310.2 - 0.0072 16.3 0.0 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin MafB19-deam PF14437.6 CDS32310.2 - 0.025 14.3 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 MafB19-like deaminase Thioredoxin_7 PF13899.6 CDS32310.2 - 0.037 14.2 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like RNA_pol_Rpb2_4 PF04566.13 CDS32310.2 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Aminotran_1_2 PF00155.21 CDS32311.2 - 3.6e-32 111.9 0.0 5.7e-32 111.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II AP_endonuc_2 PF01261.24 CDS32311.2 - 0.0057 16.1 0.2 0.02 14.3 0.2 2.0 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel PDZ PF00595.24 CDS32312.2 - 1.1e-35 121.8 0.1 4.2e-13 49.5 0.1 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CDS32312.2 - 9.3e-24 83.0 0.1 2.5e-06 27.2 0.1 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CDS32312.2 - 6.1e-09 36.1 0.0 0.008 16.5 0.0 3.3 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 CDS32312.2 - 0.022 14.7 0.0 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Tricorn protease PDZ domain PDZ PF00595.24 CDS32313.1 - 9.9e-42 141.2 0.0 7.3e-12 45.5 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CDS32313.1 - 1.7e-34 117.4 4.2 1e-12 47.7 0.1 4.5 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CDS32313.1 - 3.6e-17 62.4 0.1 0.012 15.9 0.0 4.5 4 0 0 4 4 4 4 PDZ domain Tricorn_PDZ PF14685.6 CDS32313.1 - 0.04 13.9 0.1 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Tricorn protease PDZ domain UPF0542 PF15086.6 CDS32316.1 - 5.3e-24 83.9 0.8 6.8e-24 83.6 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DUF2149 PF09919.9 CDS32316.1 - 0.0095 16.2 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) TMEM100 PF16311.5 CDS32316.1 - 0.018 14.6 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 DUF4752 PF15944.5 CDS32316.1 - 0.04 14.0 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) DUF2975 PF11188.8 CDS32316.1 - 0.048 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) OAD_gamma PF04277.13 CDS32316.1 - 0.091 13.4 0.2 0.13 12.8 0.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MMR_HSR1 PF01926.23 CDS32317.1 - 5.3e-11 42.6 0.0 1.8e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS32317.1 - 0.0017 17.9 0.5 0.0078 15.8 0.2 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDS32317.1 - 0.0085 16.0 0.5 2.2 8.2 0.1 3.3 4 0 0 4 4 4 1 RsgA GTPase Dynamin_N PF00350.23 CDS32317.1 - 0.031 14.3 0.1 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Dynamin family IIGP PF05049.13 CDS32317.1 - 0.047 12.7 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.12 CDS32317.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 CDS32317.1 - 0.13 11.2 0.1 0.28 10.1 0.1 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DnaB_bind PF10410.9 CDS32317.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase AAA_16 PF13191.6 CDS32317.1 - 0.14 12.5 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 CDS32317.1 - 0.33 10.3 0.4 1.4 8.2 0.1 2.2 2 1 0 2 2 2 0 AIG1 family UTP15_C PF09384.10 CDS32318.1 - 9e-15 54.6 0.2 1.8e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CDS32318.1 - 7.5e-05 23.4 0.3 6.5 7.8 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32318.1 - 0.006 16.9 0.0 4 7.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BCDHK_Adom3 PF10436.9 CDS32319.1 - 2.2e-44 151.1 0.0 3.1e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CDS32319.1 - 6.6e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDS32319.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPH-II PF12011.8 CDS32320.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 RNA helicase NPH-II DNA_ligase_A_M PF01068.21 CDS32321.1 - 5.3e-55 186.2 0.0 9e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDS32321.1 - 6.7e-27 94.9 0.7 6.7e-27 94.9 0.7 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDS32321.1 - 8.2e-13 48.8 0.0 2.8e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CDS32321.1 - 3.4e-07 30.7 0.1 6.7e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 CDS32321.1 - 4.2e-05 23.7 0.0 9.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 CDS32321.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mRNA_cap_enzyme PF01331.19 CDS32321.1 - 0.02 14.7 0.1 0.12 12.1 0.1 2.3 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain MSA-2c PF12238.8 CDS32322.1 - 0.031 14.3 5.7 0.1 12.6 5.7 1.7 1 1 0 1 1 1 0 Merozoite surface antigen 2c LRR_8 PF13855.6 CDS32323.1 - 2.8e-11 43.0 18.5 2.5e-07 30.3 2.5 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CDS32323.1 - 4.4e-11 42.8 17.9 2.1e-07 31.1 3.4 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS32323.1 - 2.5e-05 24.2 13.7 0.056 14.0 0.7 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 CDS32323.1 - 0.31 11.2 20.6 1.5 9.1 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat FYVE PF01363.21 CDS32324.1 - 8e-09 35.5 7.3 1.8e-08 34.4 2.0 3.0 3 0 0 3 3 3 1 FYVE zinc finger Rbsn PF11464.8 CDS32324.1 - 4.3e-05 23.1 1.9 0.00014 21.5 1.9 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2H2 PF00096.26 CDS32324.1 - 0.011 16.1 0.2 0.011 16.1 0.2 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS32324.1 - 0.043 14.7 0.6 0.043 14.7 0.6 5.0 6 0 0 6 6 6 0 C2H2-type zinc finger APG6_N PF17675.1 CDS32324.1 - 0.12 13.0 2.6 2.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region zf_UBZ PF18439.1 CDS32324.1 - 0.31 10.7 4.1 8.8 6.0 0.3 3.4 3 1 0 3 3 3 0 Ubiquitin-Binding Zinc Finger ABC_tran_CTD PF16326.5 CDS32324.1 - 4.9 7.5 6.8 17 5.8 0.4 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain zf-RING_UBOX PF13445.6 CDS32324.1 - 9.7 6.3 10.7 3.8 7.6 2.5 3.1 3 0 0 3 3 3 0 RING-type zinc-finger Pkinase PF00069.25 CDS32325.1 - 1.2e-62 211.7 0.0 1.8e-60 204.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32325.1 - 5.5e-35 120.9 0.0 2.6e-34 118.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CDS32325.1 - 4.3e-10 39.2 0.1 8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CDS32325.1 - 3.7e-06 26.5 0.0 7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS32325.1 - 0.0022 17.4 0.1 0.0037 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS32325.1 - 0.026 14.1 0.3 0.052 13.1 0.3 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CDS32325.1 - 0.029 13.3 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain BK_channel_a PF03493.18 CDS32326.1 - 4.5e-35 119.8 0.0 2e-33 114.5 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CDS32326.1 - 1.2e-15 57.5 11.2 2.5e-15 56.4 11.2 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDS32326.1 - 5.7e-13 48.6 4.9 5.7e-13 48.6 4.9 2.2 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 CDS32326.1 - 0.00076 19.7 0.2 0.0034 17.6 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain DJ-1_PfpI PF01965.24 CDS32327.1 - 2.8e-42 144.3 0.0 3.2e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CDS32327.1 - 0.0036 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 CDS32327.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain GTP_EFTU PF00009.27 CDS32328.1 - 1.1e-43 149.1 0.0 3.5e-43 147.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDS32328.1 - 3.7e-25 88.4 0.2 9.7e-25 87.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDS32328.1 - 1.3e-08 35.1 0.2 2.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDS32328.1 - 0.0026 17.8 0.0 0.0071 16.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FLYWCH PF04500.16 CDS32329.1 - 5.3e-10 39.3 0.2 9.8e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain THEG4 PF15834.5 CDS32329.1 - 0.12 12.4 1.2 8.1 6.4 0.6 2.5 2 0 0 2 2 2 0 Testis highly expressed protein 4 DUF4498 PF14926.6 CDS32330.1 - 9.1e-44 149.6 0.7 1.6e-43 148.8 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Sema PF01403.19 CDS32330.1 - 9e-27 93.9 0.0 6.6e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 Sema domain PSI PF01437.25 CDS32330.1 - 2.6e-06 27.9 2.2 9.3e-06 26.1 2.2 2.0 1 0 0 1 1 1 1 Plexin repeat TSP_1 PF00090.19 CDS32330.1 - 0.072 13.3 10.6 0.15 12.3 1.3 2.9 2 0 0 2 2 2 0 Thrombospondin type 1 domain CAP_N PF01213.19 CDS32331.1 - 4e-32 112.0 0.0 9.7e-31 107.4 0.0 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal WH2 PF02205.20 CDS32331.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 WH2 motif Ank_2 PF12796.7 CDS32332.1 - 1.1e-59 198.9 0.3 1.2e-16 61.0 0.1 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 CDS32332.1 - 3e-29 100.1 0.9 1.3e-05 25.5 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CDS32332.1 - 8.1e-29 96.5 3.9 0.0006 20.1 0.0 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 CDS32332.1 - 3e-27 94.6 1.3 5.6e-13 49.1 0.1 6.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS32332.1 - 1.5e-21 76.2 5.8 2.1e-06 27.9 0.3 6.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) SHE3 PF17078.5 CDS32332.1 - 0.38 10.4 4.6 0.27 10.9 2.9 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DSPc PF00782.20 CDS32333.1 - 2e-28 98.8 0.0 2.5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS32333.1 - 0.029 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SKG6 PF08693.10 CDS32334.1 - 0.0038 16.6 0.3 0.0038 16.6 0.3 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 CDS32334.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.5 1 1 1 2 2 2 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 CDS32334.1 - 0.017 14.8 4.2 0.017 14.8 4.2 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRRC37AB_C PF14914.6 CDS32334.1 - 0.021 14.7 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF4448 PF14610.6 CDS32334.1 - 0.039 13.7 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) COX2_TM PF02790.15 CDS32334.1 - 0.047 13.8 1.4 0.15 12.2 0.1 2.0 1 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain PRIMA1 PF16101.5 CDS32334.1 - 0.1 12.6 3.5 0.057 13.4 1.9 1.5 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 CDS32334.1 - 0.12 13.3 0.2 0.36 11.7 0.3 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 CDS32334.1 - 5.2 6.9 7.8 0.26 11.1 1.2 2.0 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor T4-gp15_tss PF16724.5 CDS32335.2 - 0.046 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser PSII_Pbs27 PF13326.6 CDS32336.1 - 0.048 14.0 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 TSSC4 PF15264.6 CDS32336.1 - 0.079 13.2 2.3 0.1 12.9 1.8 1.6 1 1 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 FAD_binding_1 PF00667.20 CDS32337.2 - 6e-50 169.9 0.0 8.9e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CDS32337.2 - 8.1e-12 45.8 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CDS32337.2 - 0.0067 16.8 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Microtub_bd PF16796.5 CDS32337.2 - 0.016 15.1 0.0 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding Flavodoxin_1 PF00258.25 CDS32337.2 - 0.02 15.1 0.0 0.055 13.7 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin NAD_binding_6 PF08030.12 CDS32337.2 - 0.041 14.0 0.4 0.9 9.7 0.0 2.8 3 1 0 3 3 3 0 Ferric reductase NAD binding domain PGM_PMM_I PF02878.16 CDS32337.2 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PDZ_6 PF17820.1 CDS32339.1 - 3.3e-09 36.5 0.1 6e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDS32339.1 - 3.4e-08 33.7 0.0 7.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Calsarcin PF05556.11 CDS32339.1 - 5e-06 26.2 0.6 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-binding protein (Calsarcin) PDZ_2 PF13180.6 CDS32339.1 - 5.2e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RBM39linker PF15519.6 CDS32339.1 - 0.43 11.7 2.4 1.8 9.7 2.4 2.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein ubiquitin PF00240.23 CDS32342.1 - 1.2e-19 69.9 0.5 2.2e-10 40.1 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 CDS32342.1 - 2.5e-09 36.8 0.1 6.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDS32343.1 - 2.7e-19 68.7 0.3 4e-07 29.7 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin family Ubiquitin_4 PF18036.1 CDS32343.1 - 1.6e-05 24.8 1.9 1 9.5 0.1 4.7 3 2 1 4 4 4 2 Ubiquitin-like domain DUF2407 PF10302.9 CDS32343.1 - 0.00023 21.7 0.0 0.12 12.9 0.0 2.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 CDS32343.1 - 0.00035 21.0 1.3 0.23 11.9 0.2 3.5 3 1 0 3 3 3 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDS32343.1 - 0.00098 18.9 1.1 0.59 10.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like BIV_Env PF05858.12 CDS32343.1 - 0.0048 15.1 0.0 0.0069 14.6 0.0 1.1 1 0 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) YukD PF08817.10 CDS32343.1 - 0.013 16.1 0.0 1.6 9.5 0.0 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Tma16 PF11176.8 CDS32343.1 - 1.1 9.1 5.9 0.71 9.7 3.7 1.9 2 0 0 2 2 2 0 Translation machinery-associated protein 16 Rap_GAP PF02145.15 CDS32344.1 - 1.5e-59 200.7 0.5 2.5e-59 200.0 0.2 1.6 2 0 0 2 2 2 1 Rap/ran-GAP CNH PF00780.22 CDS32344.1 - 9e-37 127.2 0.1 7.7e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 CNH domain POTRA_1 PF08478.10 CDS32345.1 - 0.006 16.8 0.3 1.2 9.5 0.1 2.8 3 0 0 3 3 3 1 POTRA domain, FtsQ-type Ofd1_CTDD PF10637.9 CDS32345.1 - 0.019 14.3 2.2 0.64 9.3 0.3 2.2 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Tau95_N PF17682.1 CDS32345.1 - 0.032 14.4 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 Tau95 Triple barrel domain PRP3 PF08572.10 CDS32346.1 - 2.2e-74 250.0 6.0 8.5e-74 248.0 6.0 2.1 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CDS32346.1 - 1.2e-41 142.2 0.3 3.8e-41 140.6 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) ubiquitin PF00240.23 CDS32346.1 - 1.6e-25 88.6 0.0 2e-08 33.8 0.0 5.0 4 0 0 4 4 4 3 Ubiquitin family zf-CW PF07496.15 CDS32346.1 - 3.6e-17 62.1 15.8 1.1e-10 41.3 3.1 2.7 2 0 0 2 2 2 2 CW-type Zinc Finger PWWP PF00855.17 CDS32346.1 - 2.7e-12 46.9 1.0 1.3e-09 38.3 0.0 3.5 3 0 0 3 3 3 1 PWWP domain Ubiquitin_2 PF14560.6 CDS32346.1 - 3.9e-11 43.2 0.8 0.0047 17.4 0.0 5.2 4 1 0 4 4 4 2 Ubiquitin-like domain Rad60-SLD PF11976.8 CDS32346.1 - 1e-07 31.6 0.9 0.0023 17.7 0.0 3.7 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDS32346.1 - 7e-07 29.2 2.1 0.056 13.5 0.1 5.3 4 1 0 4 4 4 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDS32346.1 - 5.3e-05 23.5 0.0 0.00042 20.6 0.0 2.6 1 0 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 CDS32346.1 - 0.038 14.5 0.0 0.4 11.2 0.0 2.9 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 RNase_T PF00929.24 CDS32347.1 - 0.022 15.3 0.0 0.11 13.1 0.0 1.9 1 1 0 1 1 1 0 Exonuclease RNase_H_2 PF13482.6 CDS32347.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily Aa_trans PF01490.18 CDS32348.1 - 1.4e-13 50.3 13.6 4.7e-13 48.6 13.6 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 CDS32350.1 - 2.1e-21 75.5 0.0 1.8e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4441 PF14536.6 CDS32350.1 - 0.018 15.2 0.3 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) RRM_3 PF08777.11 CDS32350.1 - 0.082 13.0 0.4 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif WW_FCH_linker PF16623.5 CDS32350.1 - 6.1 7.7 14.7 0.31 11.8 0.5 3.7 3 1 0 3 3 3 0 Unstructured linker region between on GAS7 protein Asparaginase PF00710.20 CDS32352.1 - 1.1e-53 181.7 0.0 1.7e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CDS32352.1 - 2.3e-26 92.3 0.0 4.1e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CDS32352.1 - 1.7e-16 60.6 0.9 9.6e-09 35.7 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS32352.1 - 2.1e-14 53.4 0.3 1.9e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32352.1 - 1.6e-11 43.3 0.5 0.00036 20.8 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDS32352.1 - 1.8e-11 43.9 1.5 0.00044 20.6 0.2 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CDS32352.1 - 2.1e-10 40.9 2.5 1.1e-05 25.8 0.3 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) MLANA PF14991.6 CDS32353.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein melan-A TPR_1 PF00515.28 CDS32354.1 - 4.6e-16 57.9 0.3 0.00016 21.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS32354.1 - 8.3e-16 56.8 0.2 0.00039 20.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS32354.1 - 2.7e-15 55.7 0.3 1.3e-11 44.0 0.1 2.7 2 1 1 3 3 3 2 TPR repeat RPAP3_C PF13877.6 CDS32354.1 - 8.2e-14 51.9 0.0 6.3e-13 49.1 0.0 2.5 3 0 0 3 3 2 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 CDS32354.1 - 6e-09 35.4 1.0 0.0098 16.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32354.1 - 6.8e-07 29.2 0.2 0.027 14.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32354.1 - 7.1e-07 29.6 0.0 0.0032 18.0 0.0 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32354.1 - 5.8e-06 26.7 0.0 0.027 15.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32354.1 - 9.5e-06 26.2 0.0 0.023 15.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32354.1 - 2.1e-05 24.5 0.0 0.032 14.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS32354.1 - 0.00024 20.9 0.5 0.6 10.3 0.1 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS32354.1 - 0.00044 20.2 3.0 1.3 9.1 0.1 4.3 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CDS32354.1 - 0.00049 20.3 0.5 0.4 11.0 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat PDGF_N PF04692.13 CDS32354.1 - 0.0011 19.7 2.5 0.86 10.4 0.0 3.5 3 0 0 3 3 3 1 Platelet-derived growth factor, N terminal region BTAD PF03704.17 CDS32354.1 - 0.002 18.6 0.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 CDS32354.1 - 0.0029 18.2 0.1 0.24 12.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Afi1 PF07792.12 CDS32354.1 - 0.046 14.2 3.9 0.096 13.2 3.9 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3856 PF12968.7 CDS32354.1 - 0.062 13.4 0.4 16 5.5 0.0 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) NRBF2_MIT PF17169.4 CDS32354.1 - 0.064 13.5 0.1 9.9 6.5 0.0 2.7 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 CDS32354.1 - 0.1 12.7 0.7 0.54 10.4 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 CDS32354.1 - 0.21 11.7 1.0 0.54 10.3 1.0 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor TPR_1 PF00515.28 CDS32355.1 - 2.8e-14 52.2 0.3 0.00028 20.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS32355.1 - 4.4e-14 51.4 0.7 0.00015 21.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CDS32355.1 - 7.9e-14 52.0 0.0 2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 CDS32355.1 - 1.6e-13 50.1 1.8 1.1e-10 41.0 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CDS32355.1 - 1.1e-08 35.6 0.2 1.2e-05 25.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32355.1 - 7.6e-07 29.6 0.3 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS32355.1 - 1.2e-06 28.2 2.8 0.026 14.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32355.1 - 1.7e-06 28.3 0.1 0.022 15.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32355.1 - 6.9e-06 26.1 0.1 0.19 11.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32355.1 - 6.7e-05 23.0 0.9 0.012 16.0 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32355.1 - 0.00028 21.1 1.5 1.6 9.1 0.0 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS32355.1 - 0.00074 19.4 1.1 0.28 11.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDS32355.1 - 0.0012 19.3 0.2 0.36 11.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 CDS32355.1 - 0.0086 16.5 0.3 0.17 12.3 0.1 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain NRBF2_MIT PF17169.4 CDS32355.1 - 0.021 15.0 0.2 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 PDGF_N PF04692.13 CDS32355.1 - 0.06 14.1 7.2 0.93 10.3 0.1 3.5 4 0 0 4 4 3 0 Platelet-derived growth factor, N terminal region MAS20 PF02064.15 CDS32355.1 - 0.072 13.2 0.4 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor Fis1_TPR_C PF14853.6 CDS32355.1 - 0.087 12.9 4.2 32 4.7 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat F5_F8_type_C PF00754.25 CDS32356.1 - 1e-51 174.3 0.9 3.4e-24 85.4 0.1 3.8 4 0 0 4 4 4 3 F5/8 type C domain WD40 PF00400.32 CDS32357.1 - 7.6e-17 61.4 5.3 0.0052 17.6 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32357.1 - 0.00081 19.6 0.0 0.0073 16.6 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS32357.1 - 0.0013 17.4 1.4 1.5 7.4 0.3 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 JAB PF01398.21 CDS32358.1 - 3.2e-18 65.8 0.0 5.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDS32358.1 - 2.7e-10 40.1 0.1 3.7e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CDS32358.1 - 5.4e-05 23.3 0.0 6.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) NDUFA12 PF05071.16 CDS32359.1 - 2.7e-30 105.1 5.5 3.2e-30 104.8 5.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 JAB PF01398.21 CDS32360.1 - 1.3e-07 31.6 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GIT_SHD PF08518.11 CDS32360.1 - 0.15 11.7 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT DNA_pol_B PF00136.21 CDS32361.1 - 1.6e-141 472.2 0.0 2.1e-141 471.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDS32361.1 - 4e-74 249.8 0.0 1.1e-73 248.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CDS32361.1 - 7.5e-18 64.8 8.2 1.5e-17 63.8 8.2 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDS32361.1 - 0.0023 16.9 0.7 0.026 13.4 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CDS32361.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB CSN8_PSD8_EIF3K PF10075.9 CDS32362.1 - 6e-29 100.9 0.1 1.3e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SH3_2 PF07653.17 CDS32362.1 - 6.9e-07 28.9 0.0 0.0024 17.5 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 CDS32362.1 - 0.00092 18.8 0.0 0.056 13.1 0.0 2.5 2 0 0 2 2 2 1 SH3 domain hSH3 PF14603.6 CDS32362.1 - 0.028 14.9 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain SH3_9 PF14604.6 CDS32362.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain Sld5 PF05916.11 CDS32363.1 - 2.4e-14 53.7 0.0 3.4e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein PRMT5 PF05185.16 CDS32364.1 - 1.2e-54 184.7 0.0 1.9e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CDS32364.1 - 2e-48 164.6 0.6 2e-48 164.6 0.6 1.5 2 0 0 2 2 2 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 CDS32364.1 - 1.7e-45 155.2 0.0 2.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Sin3_corepress PF08295.12 CDS32365.1 - 1.1e-31 108.8 0.4 3.9e-31 107.0 0.4 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 CDS32365.1 - 2.9e-31 109.3 7.3 8e-30 104.5 0.7 3.5 4 0 0 4 4 4 2 C-terminal domain of Sin3a protein PAH PF02671.21 CDS32365.1 - 6.5e-30 103.0 11.2 1.5e-13 50.6 0.0 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat FMN_dh PF01070.18 CDS32365.1 - 0.033 13.2 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Myb_DNA-bind_7 PF15963.5 CDS32365.1 - 0.26 11.2 1.8 0.91 9.5 0.3 2.6 2 0 0 2 2 2 0 Myb DNA-binding like Glyco_transf_24 PF18404.1 CDS32366.1 - 3.4e-149 495.6 2.5 6e-149 494.7 2.5 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CDS32366.1 - 1.2e-51 176.1 0.0 1.3e-46 159.6 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CDS32366.1 - 3.9e-37 127.2 0.9 3.1e-35 121.0 0.6 3.1 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CDS32366.1 - 1.4e-34 118.4 0.0 4.2e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 CDS32366.1 - 3.8e-31 108.4 0.0 7.3e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CDS32366.1 - 1.2e-28 100.6 0.0 1.1e-25 90.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CDS32366.1 - 4.7e-06 26.3 0.7 9.2e-06 25.4 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.31 CDS32367.1 - 0.0063 16.7 0.2 0.0063 16.7 0.2 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Strabismus PF06638.11 CDS32368.1 - 5.5e-54 183.7 0.4 1.9e-26 92.8 0.0 4.1 3 1 1 4 4 4 3 Strabismus protein Colicin_V PF02674.16 CDS32368.1 - 0.12 12.4 0.3 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 Colicin V production protein RhoGAP PF00620.27 CDS32369.2 - 1.4e-21 76.9 0.1 4.1e-12 46.2 0.1 2.3 2 0 0 2 2 2 2 RhoGAP domain Sec5 PF15469.6 CDS32369.2 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 HEAT_UF PF18817.1 CDS32369.2 - 0.17 12.2 0.2 0.46 10.8 0.2 1.7 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 SAC3_GANP PF03399.16 CDS32370.1 - 3.6e-101 338.4 0.1 5.6e-101 337.8 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDS32370.1 - 0.0097 15.9 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family zf-H2C2_2 PF13465.6 CDS32371.1 - 1.5e-21 75.8 17.8 1.3e-07 31.7 0.2 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDS32371.1 - 1e-20 72.9 21.6 2.1e-06 27.8 0.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type Lactamase_B PF00753.27 CDS32371.1 - 3.1e-13 50.2 0.5 2e-11 44.3 0.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-C2H2_4 PF13894.6 CDS32371.1 - 1.3e-12 47.4 20.0 0.002 18.8 0.3 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS32371.1 - 2.2e-05 24.3 16.3 0.46 10.5 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CDS32371.1 - 0.00053 20.0 9.9 0.0022 18.1 1.2 2.9 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_jaz PF12171.8 CDS32371.1 - 0.00075 19.7 3.1 7.3 7.0 0.0 4.4 3 1 1 4 4 4 1 Zinc-finger double-stranded RNA-binding Lactamase_B_2 PF12706.7 CDS32371.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zinc_ribbon_15 PF17032.5 CDS32371.1 - 0.0056 17.4 4.1 0.7 10.7 0.9 2.7 1 1 1 2 2 2 1 zinc-ribbon family TRAF6_Z2 PF18048.1 CDS32371.1 - 0.013 15.6 0.6 0.013 15.6 0.6 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-Di19 PF05605.12 CDS32371.1 - 0.02 15.2 1.2 0.02 15.2 1.2 3.2 2 1 2 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding HTH_1 PF00126.27 CDS32371.1 - 0.037 14.0 0.0 0.15 12.0 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family zf_UBZ PF18439.1 CDS32371.1 - 0.12 11.9 7.3 2.1 8.0 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 CDS32371.1 - 0.37 11.3 7.2 1.4 9.4 0.0 3.9 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CDS32371.1 - 0.77 10.2 12.5 4.9 7.7 0.4 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 CDS32371.1 - 0.79 9.7 9.8 1.7 8.6 1.0 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain DZR PF12773.7 CDS32371.1 - 2.3 8.3 10.4 3.9e+02 1.2 10.4 3.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.7 CDS32371.1 - 2.4 8.5 11.9 6 7.3 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDS32371.1 - 2.6 7.9 13.7 0.97 9.2 0.4 3.7 4 0 0 4 4 3 0 zinc-finger C2H2-type CpXC PF14353.6 CDS32371.1 - 4 7.5 6.3 47 4.1 0.1 4.0 3 2 1 4 4 4 0 CpXC protein zinc_ribbon_9 PF14369.6 CDS32371.1 - 4.2 7.7 7.1 3.2 8.1 0.1 3.6 4 0 0 4 4 3 0 zinc-ribbon Zf_RING PF16744.5 CDS32371.1 - 6.2 7.0 6.3 4 7.6 1.1 3.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF2157 PF09925.9 CDS32373.1 - 0.058 13.2 0.7 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) HEAT PF02985.22 CDS32374.1 - 0.0014 18.7 1.8 0.25 11.7 0.2 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 CDS32374.1 - 0.0047 17.4 0.8 0.11 13.0 0.1 3.4 3 0 0 3 3 3 1 HEAT-like repeat CLASP_N PF12348.8 CDS32374.1 - 0.0066 16.0 0.7 0.0066 16.0 0.7 2.9 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 CDS32374.1 - 0.015 15.7 6.9 3.7 8.0 0.1 4.6 3 1 0 3 3 3 0 HEAT repeats GLTP PF08718.11 CDS32374.1 - 0.11 12.7 0.1 0.38 11.0 0.1 1.9 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) zf-C2H2 PF00096.26 CDS32376.1 - 2e-07 31.1 22.4 0.00029 21.1 0.8 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS32376.1 - 9.2e-07 29.2 17.7 0.0037 18.0 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 CDS32376.1 - 9.7e-06 25.8 10.5 0.00027 21.2 2.3 2.6 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CDS32376.1 - 0.013 15.5 3.2 0.013 15.5 3.2 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS32376.1 - 0.021 15.2 0.5 0.021 15.2 0.5 3.7 4 0 0 4 4 3 0 Zinc-finger double domain zf-met PF12874.7 CDS32376.1 - 0.21 12.0 8.8 2.9 8.4 0.2 3.1 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 CDS32376.1 - 0.24 11.4 11.9 0.21 11.7 1.3 3.0 2 1 1 3 3 2 0 BED zinc finger Actin_micro PF17003.5 CDS32376.1 - 0.29 10.3 8.5 13 4.9 8.5 2.7 1 1 0 1 1 1 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 CDS32376.1 - 0.55 9.9 10.4 0.78 9.4 0.0 3.0 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 CDS32376.1 - 0.61 10.8 7.7 4.4 8.0 0.5 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 CDS32376.1 - 0.68 10.0 10.8 2.8 8.1 7.9 2.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zinc_ribbon_10 PF10058.9 CDS32376.1 - 0.91 9.3 5.4 0.28 10.9 1.7 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF629 PF04780.12 CDS32376.1 - 4.9 5.6 6.7 2.8 6.4 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF629) Zn-ribbon_8 PF09723.10 CDS32376.1 - 9 6.5 7.0 2.5 8.3 1.8 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DEAD PF00270.29 CDS32377.1 - 3.1e-25 89.0 0.0 4.8e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS32377.1 - 9.9e-24 83.8 0.0 2.4e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS32377.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDS32377.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1e PF01406.19 CDS32379.1 - 2.1e-122 408.2 0.0 3e-122 407.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CDS32379.1 - 5.3e-06 25.4 0.3 0.00083 18.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDS32379.1 - 0.00087 17.7 0.0 0.0068 14.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CDS32379.1 - 0.017 14.1 0.0 0.067 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain FliG_C PF01706.16 CDS32379.1 - 0.017 15.3 0.3 0.95 9.7 0.0 3.3 3 0 0 3 3 3 0 FliG C-terminal domain MRP-S33 PF08293.11 CDS32379.1 - 1 9.6 4.3 1.2 9.4 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 DUF389 PF04087.14 CDS32381.1 - 8.8e-34 116.6 11.4 1.4e-33 115.9 11.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DUF2207 PF09972.9 CDS32381.1 - 7.5 5.2 6.3 2.3 6.9 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Bestrophin PF01062.21 CDS32382.1 - 3.5e-72 243.3 1.7 4e-72 243.1 1.7 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Peptidase_M3 PF01432.20 CDS32383.1 - 1.4e-74 252.1 0.0 8e-73 246.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M3 Bestrophin PF01062.21 CDS32383.1 - 2.4e-19 69.8 1.9 1.8e-13 50.5 0.2 2.2 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel Tropomyosin_1 PF12718.7 CDS32383.1 - 0.035 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Tropomyosin like Peptidase_M91 PF14891.6 CDS32383.1 - 0.14 12.4 0.4 0.71 10.2 0.0 2.1 3 0 0 3 3 3 0 Effector protein tRNA_synthFbeta PF17759.1 CDS32384.1 - 1.2e-47 162.2 0.0 1.7e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CDS32384.1 - 2.9e-32 110.7 0.0 9.1e-32 109.1 0.0 1.9 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CDS32384.1 - 3.4e-26 92.0 0.0 5.6e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CDS32384.1 - 9.4e-18 64.3 0.0 1.2e-14 54.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 CDS32384.1 - 0.16 11.9 0.1 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Bestrophin PF01062.21 CDS32385.1 - 1.6e-73 247.7 2.2 2.7e-73 246.9 2.2 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TPT PF03151.16 CDS32385.1 - 3.4e-08 33.2 12.1 6.6e-08 32.2 12.1 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family URO-D PF01208.17 CDS32386.1 - 2.1e-131 438.2 0.0 2.4e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PqqA PF08042.11 CDS32386.1 - 2.6 8.2 4.4 4.3 7.5 0.1 3.1 3 0 0 3 3 3 0 PqqA family GRIP PF01465.20 CDS32387.1 - 6.3e-12 45.2 0.0 4e-11 42.6 0.0 2.5 2 0 0 2 2 2 1 GRIP domain Rab_bind PF16704.5 CDS32387.1 - 5.9e-06 26.2 3.9 5.9e-06 26.2 3.9 4.7 6 1 1 7 7 7 1 Rab binding domain NOG1_N PF17835.1 CDS32387.1 - 0.16 11.9 0.1 0.16 11.9 0.1 4.0 5 0 0 5 5 5 0 NOG1 N-terminal helical domain Spc7 PF08317.11 CDS32387.1 - 0.18 10.6 88.9 0.011 14.7 6.6 7.5 6 3 3 9 9 9 0 Spc7 kinetochore protein Bcr-Abl_Oligo PF09036.10 CDS32387.1 - 2.6 8.1 18.1 4.7 7.3 0.1 5.9 4 2 1 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain Chromo_shadow PF01393.19 CDS32388.1 - 6.1e-18 64.7 1.0 2.1e-17 62.9 0.1 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 CDS32388.1 - 7.8e-15 54.5 1.2 2.1e-12 46.8 1.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDS32389.1 - 7.3e-27 93.2 0.1 1.1e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CDS32389.1 - 4.1e-24 84.2 0.3 8.2e-18 64.1 0.5 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Raftlin PF15250.6 CDS32389.1 - 0.013 14.3 1.2 0.016 14.0 1.2 1.1 1 0 0 1 1 1 0 Raftlin Ank_2 PF12796.7 CDS32390.2 - 3.5e-22 78.8 8.2 1e-07 32.4 0.3 4.4 5 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32390.2 - 1.4e-15 57.4 7.2 0.00028 21.4 0.2 6.9 4 3 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS32390.2 - 1.1e-14 54.3 9.7 5.8e-07 29.7 0.4 6.4 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 CDS32390.2 - 1.5e-14 53.7 13.4 0.023 15.1 0.1 7.5 7 1 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 CDS32390.2 - 2.4e-14 52.0 5.1 0.86 10.4 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Patatin PF01734.22 CDS32390.2 - 5.6e-08 33.2 0.0 1.3e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase RhoGEF PF00621.20 CDS32391.2 - 6.6e-17 62.3 5.3 2.1e-15 57.5 5.3 2.6 1 1 0 1 1 1 1 RhoGEF domain KLRAQ PF10205.9 CDS32391.2 - 0.074 13.3 0.3 0.66 10.2 0.0 2.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein VIR_N PF15912.5 CDS32393.2 - 2.8e-18 66.5 3.0 6.6e-18 65.3 3.0 1.5 1 0 0 1 1 1 1 Virilizer, N-terminal zf-C2H2 PF00096.26 CDS32393.2 - 1e-05 25.7 21.9 0.01 16.3 0.4 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS32393.2 - 0.083 13.8 22.3 0.22 12.4 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDS32393.2 - 0.24 11.3 5.4 0.99 9.4 0.7 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 CDS32393.2 - 5.3 7.6 12.6 1.5 9.3 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDS32393.2 - 5.6 7.4 11.5 22 5.5 5.7 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDS32393.2 - 6.8 7.1 8.0 5.7 7.4 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FH2 PF02181.23 CDS32394.2 - 3e-70 237.2 4.9 3e-70 237.2 4.9 2.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Formin_GBD_N PF18382.1 CDS32394.2 - 3.7e-11 43.3 0.2 1.7e-10 41.2 0.1 2.2 2 0 0 2 2 2 1 Formin N-terminal GTPase-binding domain Drf_FH3 PF06367.16 CDS32394.2 - 0.0011 18.6 0.1 0.0082 15.8 0.0 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain Menin PF05053.13 CDS32395.2 - 5.7e-99 332.3 7.4 1.4e-44 152.6 0.0 5.6 5 1 0 5 5 5 5 Menin Guanylate_kin PF00625.21 CDS32398.1 - 4.1e-28 98.3 0.0 7.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.17 CDS32398.1 - 3.9e-07 29.7 0.0 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain PDZ PF00595.24 CDS32398.1 - 5.6e-07 29.8 0.5 1.2e-06 28.8 0.5 1.6 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.28 CDS32398.1 - 8.4e-05 22.1 0.1 0.00026 20.5 0.1 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 CDS32398.1 - 0.00027 20.7 0.2 0.0011 18.7 0.2 2.1 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.6 CDS32398.1 - 0.002 18.0 0.0 0.008 16.0 0.0 2.1 1 1 0 1 1 1 1 Variant SH3 domain Apolipoprotein PF01442.18 CDS32399.2 - 0.013 15.4 36.6 0.29 11.0 25.8 4.7 3 1 2 5 5 5 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CDS32399.2 - 0.024 14.7 32.9 2.1 8.4 7.1 5.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 CDS32399.2 - 0.033 14.7 1.2 0.033 14.7 1.2 5.1 2 1 2 5 5 5 0 Syntaxin 6, N-terminal Prominin PF05478.11 CDS32399.2 - 0.035 12.1 29.2 0.12 10.3 12.3 2.4 1 1 0 2 2 2 0 Prominin ApoLp-III PF07464.11 CDS32399.2 - 0.062 13.4 27.4 0.094 12.8 13.0 3.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Rsa3 PF14615.6 CDS32399.2 - 0.086 12.4 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DUF1664 PF07889.12 CDS32399.2 - 0.27 11.3 29.3 11 6.0 0.2 5.9 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) AI-2E_transport PF01594.16 CDS32399.2 - 0.41 9.7 9.1 0.96 8.5 0.1 3.2 3 0 0 3 3 3 0 AI-2E family transporter CCDC154 PF15450.6 CDS32399.2 - 0.53 8.8 33.4 25 3.2 33.4 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 154 ING PF12998.7 CDS32399.2 - 0.8 10.3 23.6 1.1 9.9 0.1 5.2 2 2 2 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF842 PF05811.13 CDS32399.2 - 1.7 8.3 15.8 1.2 8.9 0.1 4.0 3 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) Focal_AT PF03623.13 CDS32399.2 - 3.9 7.5 16.7 0.46 10.5 0.3 4.3 3 1 1 4 4 4 0 Focal adhesion targeting region ATPase PF06745.13 CDS32399.2 - 4.3 6.6 14.0 0.13 11.6 3.0 2.9 3 0 0 3 3 3 0 KaiC DUF1870 PF08965.10 CDS32399.2 - 4.5 7.3 6.8 7.3 6.6 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1870) CorA PF01544.18 CDS32399.2 - 4.7 6.4 25.0 2.1 7.6 6.2 3.9 2 1 2 4 4 4 0 CorA-like Mg2+ transporter protein DUF2203 PF09969.9 CDS32399.2 - 5.2 7.8 21.8 11 6.8 3.1 4.9 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Lectin_N PF03954.14 CDS32399.2 - 5.4 6.8 19.1 0.3 10.8 4.4 4.0 3 2 2 5 5 5 0 Hepatic lectin, N-terminal domain Exonuc_VII_L PF02601.15 CDS32399.2 - 7.2 6.1 31.0 44 3.5 13.0 3.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Synaptobrevin PF00957.21 CDS32400.2 - 4.9e-22 77.5 1.0 7.8e-22 76.9 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Orf78 PF06024.12 CDS32400.2 - 0.0063 16.8 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Orf78 (ac78) DUF2207 PF09972.9 CDS32400.2 - 0.027 13.3 0.2 0.035 12.9 0.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4854 PF16146.5 CDS32400.2 - 0.05 13.9 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Fzo_mitofusin PF04799.13 CDS32400.2 - 0.072 12.6 2.3 0.16 11.5 2.1 1.6 1 1 0 1 1 1 0 fzo-like conserved region AAA_9 PF12781.7 CDS32401.1 - 0.0041 16.3 0.2 0.0049 16.0 0.2 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region Lectin_N PF03954.14 CDS32401.1 - 0.0043 16.8 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain zf-CCHC PF00098.23 CDS32403.1 - 2.3e-10 40.0 28.6 0.00011 22.1 0.6 4.7 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 CDS32403.1 - 0.00061 19.5 32.8 0.33 10.7 2.1 5.4 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CDS32403.1 - 0.0068 16.3 25.8 0.071 13.1 0.2 5.4 3 1 2 5 5 5 3 Zinc knuckle PolC_DP2 PF03833.13 CDS32403.1 - 5.5 4.7 6.2 9.3 4.0 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ank_2 PF12796.7 CDS32404.1 - 8.8e-37 125.6 1.0 8.7e-16 58.3 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 CDS32404.1 - 1.2e-31 109.6 15.5 1.2e-31 109.6 15.5 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CDS32404.1 - 1.1e-23 83.3 11.4 1.5e-09 38.2 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32404.1 - 1.3e-23 80.5 1.4 5.5e-05 23.3 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CDS32404.1 - 2e-23 82.1 4.1 1.1e-09 38.3 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS32404.1 - 5e-19 67.8 0.5 0.0023 18.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat DUF5592 PF17332.2 CDS32404.1 - 1.3 9.6 4.2 4.1 8.0 4.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5592) Ssl1 PF04056.14 CDS32405.1 - 1.1e-67 227.6 0.2 1.7e-67 227.0 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CDS32405.1 - 5.4e-11 43.1 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CDS32405.1 - 1e-08 35.2 26.8 3.4e-08 33.6 15.5 4.4 4 1 1 5 5 5 2 TFIIH C1-like domain VWA PF00092.28 CDS32405.1 - 7.6e-05 23.0 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 CDS32405.1 - 9.6 6.3 24.2 1.5 9.0 1.3 3.7 3 1 0 3 3 3 0 Double zinc ribbon KH_1 PF00013.29 CDS32407.1 - 3.7e-20 71.5 5.3 1.2e-10 41.1 0.8 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDS32407.1 - 1e-05 25.3 0.7 0.19 11.5 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CDS32407.1 - 0.00052 20.0 1.9 0.14 12.3 0.3 2.5 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 CDS32407.1 - 0.069 13.0 1.8 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 KH domain NIF PF03031.18 CDS32408.1 - 3.5e-21 75.6 0.0 7.2e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 CDS32408.1 - 0.0031 17.3 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dynein_light PF01221.18 CDS32410.1 - 3.8e-16 59.2 0.0 4.2e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Flavokinase PF01687.17 CDS32414.1 - 1.7e-25 89.4 0.0 2.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Surp PF01805.20 CDS32417.1 - 6.6e-17 61.3 0.1 1.7e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 CDS32417.1 - 9.2e-13 48.8 0.1 2.7e-12 47.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DBR1 PF05011.13 CDS32418.1 - 3.2e-32 111.9 0.0 5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CDS32418.1 - 1.6e-09 38.6 0.2 3e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDS32418.1 - 0.033 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Malectin PF11721.8 CDS32419.1 - 3.3e-37 128.1 0.0 4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Malectin domain Ribosomal_L35p PF01632.19 CDS32420.1 - 2.6e-06 27.8 0.0 3.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 Lipoxygenase PF00305.19 CDS32421.1 - 3.1e-34 118.5 0.0 6.8e-33 114.0 0.0 2.3 2 1 0 2 2 2 2 Lipoxygenase TPR_2 PF07719.17 CDS32422.1 - 8.9e-13 47.3 7.4 0.00026 20.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32422.1 - 6.1e-12 44.8 8.2 1.3e-06 28.0 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS32422.1 - 1.3e-07 31.3 5.2 0.015 15.4 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32422.1 - 1.7e-06 28.1 0.9 4.4e-06 26.7 0.7 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32422.1 - 4.3e-05 23.7 3.0 0.0086 16.3 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32422.1 - 7.3e-05 23.3 1.8 0.077 13.9 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS32422.1 - 0.00026 20.6 9.2 0.076 12.7 0.1 3.8 3 2 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 CDS32422.1 - 0.00093 19.4 3.5 0.055 13.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDS32422.1 - 0.002 17.4 0.2 0.056 12.7 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CDS32422.1 - 0.0054 16.8 0.6 1.7 8.7 0.3 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CDS32422.1 - 0.0075 16.8 2.6 0.017 15.6 1.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 CDS32422.1 - 0.0097 16.0 0.1 0.016 15.3 0.1 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 CDS32422.1 - 0.024 15.2 0.6 1.6 9.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32422.1 - 0.028 15.0 5.6 0.43 11.3 0.5 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat YabA PF06156.13 CDS32422.1 - 0.11 13.2 5.3 0.27 11.9 1.2 2.7 2 1 1 3 3 3 0 Initiation control protein YabA Kdo PF06293.14 CDS32423.1 - 2.7e-08 33.4 0.6 1e-07 31.5 0.6 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDS32423.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDS32423.1 - 3.7e-05 23.8 0.2 0.037 13.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CDS32423.1 - 0.00047 19.5 0.1 0.00063 19.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDS32423.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 CDS32423.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 CDS32423.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CDS32423.1 - 0.053 12.4 0.1 0.087 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) YrbL-PhoP_reg PF10707.9 CDS32423.1 - 0.08 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TEP1_N PF05386.11 CDS32423.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 TEP1 N-terminal domain PI3K_P85_iSH2 PF16454.5 CDS32424.1 - 0.0036 16.9 33.6 0.041 13.5 8.9 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Uso1_p115_C PF04871.13 CDS32424.1 - 0.034 14.5 34.5 1.2 9.5 5.2 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 CDS32424.1 - 0.037 13.4 37.7 0.11 11.8 11.6 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 CDS32424.1 - 0.043 12.4 6.2 0.047 12.2 6.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 CDS32424.1 - 0.11 12.7 41.1 0.24 11.6 28.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDS32424.1 - 0.32 9.8 36.3 0.41 9.5 16.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 CDS32424.1 - 0.33 11.4 38.6 2.6 8.6 8.4 4.6 3 2 1 4 4 4 0 Cell division protein ZapB DUF948 PF06103.11 CDS32424.1 - 0.34 11.2 19.5 2.3 8.5 1.1 4.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Metal_resist PF13801.6 CDS32424.1 - 0.51 10.5 5.2 1.5 9.1 0.2 2.7 2 1 0 2 2 2 0 Heavy-metal resistance Laminin_II PF06009.12 CDS32424.1 - 0.84 9.7 30.2 0.037 14.0 4.5 3.5 1 1 2 3 3 3 0 Laminin Domain II DUF4472 PF14739.6 CDS32424.1 - 0.95 10.2 25.1 0.66 10.7 7.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) KASH_CCD PF14662.6 CDS32424.1 - 0.96 9.2 39.0 0.036 13.9 23.9 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 CDS32424.1 - 1.2 8.3 37.3 15 4.7 4.5 3.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Sec34 PF04136.15 CDS32424.1 - 1.2 9.0 21.5 0.37 10.7 1.4 3.4 2 1 2 4 4 4 0 Sec34-like family Fez1 PF06818.15 CDS32424.1 - 1.2 9.5 34.3 1 9.8 24.6 2.9 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 CDS32424.1 - 1.4 8.1 29.0 0.3 10.4 13.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 CDS32424.1 - 1.6 9.0 39.0 6.4 7.0 17.7 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 YabA PF06156.13 CDS32424.1 - 2 9.1 30.1 5.3 7.7 2.4 4.0 1 1 2 3 3 3 0 Initiation control protein YabA JIP_LZII PF16471.5 CDS32424.1 - 2.2 8.5 26.7 0.33 11.1 0.9 4.2 3 2 2 5 5 5 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 CDS32424.1 - 2.2 8.3 37.0 2.9 7.9 11.3 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus IclR PF01614.18 CDS32424.1 - 2.4 8.0 5.3 25 4.7 0.3 3.2 1 1 2 3 3 3 0 Bacterial transcriptional regulator LPP PF04728.13 CDS32424.1 - 2.7 8.5 22.8 0.49 10.8 4.3 5.1 2 2 1 4 4 4 0 Lipoprotein leucine-zipper COG2 PF06148.11 CDS32424.1 - 2.8 8.0 21.0 1.6 8.8 1.8 3.4 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 CDS32424.1 - 4.9 7.2 43.3 0.94 9.5 10.5 4.0 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 CDS32424.1 - 6.8 6.9 41.7 0.059 13.5 15.3 4.6 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 CDS32424.1 - 9 6.8 40.7 63 4.1 17.0 3.8 1 1 1 2 2 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CDS32424.1 - 9.1 6.3 17.4 13 5.9 8.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 CDS32424.1 - 9.5 5.2 38.2 0.66 9.0 20.5 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myelin_PLP PF01275.19 CDS32426.1 - 6.4e-07 29.5 14.2 0.00012 22.0 9.2 2.2 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) DUF3810 PF12725.7 CDS32426.1 - 0.02 14.3 2.6 0.21 10.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CitMHS PF03600.16 CDS32426.1 - 0.16 11.1 4.2 5.1 6.2 1.3 2.2 2 0 0 2 2 2 0 Citrate transporter DUF2207 PF09972.9 CDS32426.1 - 0.2 10.4 1.4 20 3.8 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Neur_chan_LBD PF02931.23 CDS32427.1 - 3.1e-31 108.5 1.8 3.9e-31 108.2 1.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS32427.1 - 1.1e-22 81.3 8.7 7.2e-20 72.1 2.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region zf-H2C2_2 PF13465.6 CDS32427.1 - 0.0099 16.3 0.2 0.018 15.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS32427.1 - 0.2 12.0 1.4 0.38 11.1 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDS32427.1 - 0.45 11.1 2.2 0.97 10.0 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type rve_3 PF13683.6 CDS32428.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain CH PF00307.31 CDS32429.1 - 5.2e-54 181.1 1.4 3.2e-29 101.3 0.1 3.6 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 CDS32429.1 - 1.3e-45 154.2 19.7 2.5e-15 56.9 2.7 4.6 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 CDS32429.1 - 6.9e-23 80.5 0.0 2.5e-22 78.7 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CDS32429.1 - 1.6e-10 40.7 0.1 3.4e-08 33.2 0.1 2.7 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.32 CDS32429.1 - 3.6e-05 23.0 0.0 0.21 11.2 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS32429.1 - 0.0001 22.6 0.3 0.00054 20.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS32429.1 - 0.00025 20.7 0.1 0.94 9.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDS32429.1 - 0.0053 16.6 0.2 0.25 11.2 0.0 3.5 3 1 1 4 4 4 1 EF-hand domain pair CH_2 PF06294.11 CDS32429.1 - 0.015 15.4 0.6 0.53 10.4 0.0 3.5 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF3461 PF11944.8 CDS32429.1 - 0.34 11.0 4.0 0.21 11.7 0.3 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3461) Ank_5 PF13857.6 CDS32432.1 - 1.1e-114 372.9 39.7 9.9e-13 48.1 0.0 16.3 9 4 7 16 16 16 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS32432.1 - 5.7e-99 324.9 21.9 5.7e-13 49.3 0.2 11.9 5 3 4 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32432.1 - 1.2e-95 312.7 25.6 3.2e-12 46.7 0.0 14.0 9 4 6 16 16 16 13 Ankyrin repeats (many copies) Ank PF00023.30 CDS32432.1 - 3.2e-89 289.8 48.2 2.9e-07 30.6 0.1 19.3 20 1 1 21 21 21 14 Ankyrin repeat Ank_3 PF13606.6 CDS32432.1 - 6.3e-81 256.6 40.0 7e-06 26.0 0.1 20.4 21 1 0 21 21 21 14 Ankyrin repeat PARP PF00644.20 CDS32432.1 - 1.4e-20 73.8 0.0 8.3e-19 67.9 0.0 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.17 CDS32432.1 - 6e-10 39.1 0.1 1.4e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS32432.1 - 6e-09 36.2 0.1 1.2e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2384 PF09722.10 CDS32432.1 - 0.06 13.4 0.2 14 5.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2384) WD40 PF00400.32 CDS32433.1 - 9.3e-21 73.8 14.2 0.0089 16.9 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32433.1 - 3.6e-05 24.0 0.1 12 6.3 0.0 4.5 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDS32433.1 - 0.001 18.5 0.0 2 7.6 0.0 3.6 2 1 1 3 3 3 1 WD40-like domain ATG16 PF08614.11 CDS32433.1 - 0.0019 18.5 15.0 0.0036 17.6 15.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) eIF2A PF08662.11 CDS32433.1 - 0.0064 16.4 0.0 3.4 7.5 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HAUS-augmin3 PF14932.6 CDS32433.1 - 0.011 15.3 8.1 0.017 14.7 8.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MAD PF05557.13 CDS32433.1 - 0.013 13.9 17.2 0.24 9.7 2.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein zf-C4H2 PF10146.9 CDS32433.1 - 0.044 14.1 3.4 0.065 13.5 3.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ABC_tran_Xtn PF12848.7 CDS32433.1 - 0.045 13.8 3.8 0.1 12.6 3.8 1.6 1 0 0 1 1 1 0 ABC transporter Ge1_WD40 PF16529.5 CDS32433.1 - 0.058 12.4 0.8 7.5 5.4 0.0 3.1 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nebulin PF00880.18 CDS32433.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Nebulin repeat PA28_beta PF02252.18 CDS32433.1 - 0.097 12.3 2.7 1.1 8.9 0.9 2.2 1 1 1 2 2 2 0 Proteasome activator pa28 beta subunit HOOK PF05622.12 CDS32433.1 - 0.12 10.6 19.1 0.16 10.1 19.1 1.1 1 0 0 1 1 1 0 HOOK protein FPP PF05911.11 CDS32433.1 - 0.14 10.4 18.0 0.18 9.9 18.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CENP-H PF05837.12 CDS32433.1 - 0.38 11.2 18.3 0.046 14.1 7.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cob_adeno_trans PF01923.18 CDS32433.1 - 1.2 9.3 4.9 0.98 9.5 2.7 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Peptidase_S46 PF10459.9 CDS32433.1 - 1.4 7.4 4.8 1.9 7.0 4.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4795 PF16043.5 CDS32433.1 - 1.4 8.4 19.0 0.6 9.7 8.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Nup54_57_C PF18570.1 CDS32433.1 - 2.2 7.9 5.3 0.42 10.2 0.4 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain DUF4407 PF14362.6 CDS32433.1 - 3.6 6.8 7.1 5.5 6.3 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 CDS32433.1 - 5.4 6.8 23.8 5.8 6.7 5.6 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 CDS32433.1 - 5.6 7.0 24.2 0.43 10.6 13.0 2.7 2 1 1 3 3 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 CDS32433.1 - 6.3 6.8 24.3 1.2 9.1 13.9 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GOLD_2 PF13897.6 CDS32434.1 - 3.2e-53 179.9 0.1 3.2e-53 179.9 0.1 2.3 2 2 1 3 3 3 1 Golgi-dynamics membrane-trafficking DUF535 PF04393.13 CDS32434.1 - 0.032 13.5 1.6 0.048 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Pkinase PF00069.25 CDS32435.1 - 3.4e-76 256.1 0.0 4.1e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32435.1 - 4.2e-38 131.1 0.0 5.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32435.1 - 3.2e-08 33.2 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDS32435.1 - 4e-06 26.9 0.0 0.039 13.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS32435.1 - 1.9e-05 23.8 0.2 2.7e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS32435.1 - 0.00022 20.6 0.1 0.00044 19.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDS32435.1 - 0.00035 20.2 0.9 0.0016 18.1 0.1 2.4 3 0 0 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 CDS32435.1 - 0.0047 15.7 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDS32435.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YukC PF10140.9 CDS32435.1 - 0.033 13.0 0.2 0.061 12.1 0.1 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC PUF PF00806.19 CDS32435.1 - 0.059 13.1 0.0 0.23 11.2 0.0 2.0 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DCP1 PF06058.13 CDS32439.2 - 5.9e-31 106.8 0.1 1.5e-30 105.6 0.1 1.7 2 0 0 2 2 2 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 CDS32439.2 - 0.00019 20.6 0.0 0.0005 19.3 0.0 1.7 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus WH1 PF00568.23 CDS32439.2 - 0.059 13.3 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 WH1 domain PH PF00169.29 CDS32440.2 - 1.8e-12 47.7 0.0 6.2e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 PH domain ArAE_2 PF10334.9 CDS32440.2 - 0.017 15.0 0.1 0.052 13.4 0.1 1.8 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Transposase_1 PF01359.18 CDS32441.1 - 5e-09 35.9 0.3 9.2e-09 35.0 0.3 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Meis_PKNOX_N PF16493.5 CDS32443.1 - 2.5e-39 133.5 1.1 2.5e-39 133.5 1.1 2.7 3 0 0 3 3 3 1 N-terminal of Homeobox Meis and PKNOX1 HLH PF00010.26 CDS32445.1 - 5.7e-05 23.0 0.7 5.7e-05 23.0 0.7 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain BAG PF02179.16 CDS32445.1 - 0.083 13.3 1.2 0.12 12.8 1.2 1.3 1 0 0 1 1 1 0 BAG domain HSP70 PF00012.20 CDS32445.1 - 0.12 10.5 2.0 0.15 10.2 2.0 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-RING_2 PF13639.6 CDS32446.1 - 1e-12 48.1 15.4 9.2e-08 32.3 2.1 2.5 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CDS32446.1 - 1.4e-10 40.9 14.1 3.2e-05 23.7 4.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS32446.1 - 3e-09 36.6 17.9 3e-06 27.0 4.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS32446.1 - 2.7e-08 33.9 15.9 0.00028 21.1 2.2 2.8 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDS32446.1 - 5.6e-07 29.5 18.3 0.00025 21.0 5.0 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS32446.1 - 8.8e-07 29.0 17.3 0.00083 19.5 6.1 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDS32446.1 - 2.2e-06 27.5 17.2 3.1e-06 27.0 4.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDS32446.1 - 9.3e-06 25.2 13.3 2.9e-05 23.6 3.1 2.4 2 1 0 2 2 2 2 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CDS32446.1 - 9.8e-06 25.3 13.2 4.3e-05 23.3 2.4 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDS32446.1 - 0.00043 20.3 13.4 0.16 12.0 1.3 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CDS32446.1 - 0.00065 19.4 10.7 0.0078 15.9 2.1 3.1 2 1 0 2 2 2 2 RING-like zinc finger zf-RING_6 PF14835.6 CDS32446.1 - 0.0031 17.4 3.5 0.0031 17.4 3.5 2.2 2 1 0 2 2 2 1 zf-RING of BARD1-type protein zf-P11 PF03854.14 CDS32446.1 - 0.0037 16.9 2.7 0.0037 16.9 2.7 4.0 3 1 1 4 4 4 1 P-11 zinc finger zf-RING_10 PF16685.5 CDS32446.1 - 0.057 13.6 2.2 0.057 13.6 2.2 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDS32446.1 - 0.11 12.2 0.7 0.11 12.2 0.7 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CDS32446.1 - 4.3 7.3 19.3 0.13 12.2 4.0 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDS32446.1 - 5 7.0 10.5 5.8 6.8 1.5 2.5 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CDS32446.1 - 5.2 7.3 12.0 0.087 13.0 2.8 2.7 2 1 1 3 3 3 0 FANCL C-terminal domain PK PF00224.21 CDS32447.1 - 2e-72 244.0 0.5 2.9e-72 243.5 0.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDS32447.1 - 3.6e-24 85.3 0.4 1.1e-23 83.7 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain DUF104 PF01954.16 CDS32447.1 - 0.13 12.7 0.2 34 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF104 T2SS-T3SS_pil_N PF13629.6 CDS32449.1 - 0.017 14.9 0.7 0.085 12.6 0.0 2.6 2 0 0 2 2 2 0 Pilus formation protein N terminal region JmjC PF02373.22 CDS32450.1 - 5.7e-42 142.7 0.1 1.7e-41 141.2 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 CDS32450.1 - 3.5e-18 65.9 2.6 5.2e-17 62.0 2.3 2.7 1 1 0 1 1 1 1 PLU-1-like protein PHD PF00628.29 CDS32450.1 - 2.2e-17 62.7 59.6 2.3e-10 40.2 6.0 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 CDS32450.1 - 2.1e-15 57.2 0.1 6.8e-15 55.5 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 CDS32450.1 - 1e-14 54.6 12.7 1e-14 54.6 12.7 3.4 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 CDS32450.1 - 2.7e-10 40.0 0.4 5.8e-10 39.0 0.4 1.6 1 0 0 1 1 1 1 jmjN domain LIAS_N PF16881.5 CDS32451.1 - 2.4e-17 63.3 0.0 5.3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CDS32451.1 - 7.2e-15 55.8 0.0 1.1e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SprT-like PF10263.9 CDS32452.1 - 8.3e-22 77.2 0.0 1.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CDS32452.1 - 2.6e-06 27.2 6.7 5.5e-06 26.2 6.7 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF812 PF05667.11 CDS32452.1 - 0.0059 15.6 2.7 0.01 14.8 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Bt_P21 PF05560.11 CDS32452.1 - 0.073 12.7 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein WD40 PF00400.32 CDS32453.1 - 7.2e-06 26.7 10.9 0.013 16.3 0.5 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat G10 PF01125.17 CDS32453.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 G10 protein SRF-TF PF00319.18 CDS32454.1 - 5.6e-16 57.8 1.2 8.3e-16 57.2 0.3 1.8 1 1 1 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PGK PF00162.19 CDS32456.1 - 3.3e-153 510.1 0.6 3.7e-153 510.0 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 CDS32456.1 - 0.19 11.8 1.7 0.36 10.9 0.0 2.3 3 0 0 3 3 3 0 PA domain Noelin-1 PF12308.8 CDS32457.1 - 0.55 10.3 3.4 4.9 7.2 0.2 3.7 3 0 0 3 3 3 0 Neurogenesis glycoprotein CPSF100_C PF13299.6 CDS32457.1 - 1.7 8.8 5.0 9.9 6.3 4.8 2.5 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Retrotran_gag_2 PF14223.6 CDS32457.1 - 1.8 8.2 4.6 1.6 8.4 0.2 3.0 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DASH_Dam1 PF08653.10 CDS32457.1 - 6.7 6.6 16.7 0.24 11.2 0.3 5.1 6 0 0 6 6 6 0 DASH complex subunit Dam1 CBP_CCPA PF17040.5 CDS32460.1 - 0.0097 16.5 0.5 0.022 15.4 0.5 1.5 1 0 0 1 1 1 1 Cellulose-complementing protein A CNH PF00780.22 CDS32461.1 - 0.00019 21.2 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 CNH domain Kelch_1 PF01344.25 CDS32462.1 - 3.3e-31 106.6 12.3 2.7e-11 42.9 0.1 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CDS32462.1 - 4.7e-26 90.2 5.8 9.6e-09 35.2 0.1 6.9 4 1 3 7 7 7 5 Kelch motif Kelch_3 PF13415.6 CDS32462.1 - 1.4e-18 66.7 3.1 8.2e-08 32.4 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS32462.1 - 2.5e-12 46.5 0.0 0.35 10.9 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CDS32462.1 - 1.6e-11 44.0 2.0 0.035 14.1 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS32462.1 - 3.7e-09 36.2 0.6 0.004 17.1 0.0 4.8 4 1 0 4 4 4 2 Kelch motif BACK PF07707.15 CDS32462.1 - 3e-07 30.5 2.9 1e-05 25.6 1.4 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch Vps39_2 PF10367.9 CDS32463.1 - 7.9e-08 32.7 1.8 1.2e-07 32.1 0.1 2.2 2 2 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CDS32463.1 - 0.00025 21.0 2.3 0.0048 16.8 0.3 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS DSPc PF00782.20 CDS32464.1 - 2.1e-19 69.6 0.0 2.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain NAP PF00956.18 CDS32465.1 - 1.3e-87 293.4 6.3 1.8e-87 292.9 6.3 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) EBV-NA3 PF05009.12 CDS32465.1 - 0.62 9.6 3.0 1.1 8.7 3.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DNA_pol_phi PF04931.13 CDS32465.1 - 6.6 4.7 11.0 15 3.5 11.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi Glycos_transf_2 PF00535.26 CDS32466.2 - 9.6e-35 119.9 0.0 1.7e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CDS32466.2 - 5.2e-15 55.8 0.5 7.9e-15 55.2 0.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CDS32466.2 - 4.2e-06 26.3 0.0 8.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CDS32466.2 - 1.5e-05 25.0 0.0 5.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDS32466.2 - 2.9e-05 23.7 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF5359 PF17313.2 CDS32466.2 - 0.19 11.7 3.1 0.37 10.8 3.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5359) TPR_19 PF14559.6 CDS32467.1 - 1.1e-16 61.1 0.4 0.00038 20.9 0.0 6.0 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32467.1 - 9e-15 54.1 12.5 0.047 14.5 0.0 10.1 10 2 3 13 13 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32467.1 - 1.1e-13 51.2 10.5 2e-05 24.7 0.1 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDS32467.1 - 1.1e-13 50.1 21.1 0.0042 17.1 0.0 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32467.1 - 8e-12 44.7 4.4 0.46 11.0 0.0 7.9 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32467.1 - 3.7e-11 43.0 4.1 0.00094 19.3 0.1 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32467.1 - 1e-10 42.1 1.6 1.8e-06 28.5 0.0 5.6 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32467.1 - 8e-09 35.0 20.6 0.15 11.9 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDS32467.1 - 4.3e-08 32.7 13.0 1.8 9.0 0.0 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32467.1 - 1.6e-07 31.5 6.2 0.077 13.3 0.1 6.0 6 1 1 7 7 5 2 Tetratricopeptide repeat BTAD PF03704.17 CDS32467.1 - 8.7e-05 23.0 5.6 0.53 10.7 0.0 4.4 5 0 0 5 5 4 2 Bacterial transcriptional activator domain DUF5588 PF17826.1 CDS32467.1 - 0.00013 21.0 4.2 0.00061 18.8 0.0 3.5 3 1 1 4 4 4 1 Family of unknown function (DUF5588) TPR_11 PF13414.6 CDS32467.1 - 0.00082 19.0 0.7 8.9 6.1 0.1 5.2 3 2 3 6 6 6 1 TPR repeat TPR_6 PF13174.6 CDS32467.1 - 0.0068 17.0 10.1 62 4.5 0.0 7.9 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDS32467.1 - 0.017 15.1 2.5 2.6 8.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDS32467.1 - 0.041 13.1 0.0 14 4.8 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDS32467.1 - 0.098 13.0 0.0 6.6 7.1 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat HMA PF00403.26 CDS32468.1 - 2.2e-09 37.6 0.4 2.5e-09 37.4 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 CDS32468.1 - 0.025 14.7 0.1 0.032 14.3 0.1 1.3 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Methyltransf_23 PF13489.6 CDS32470.1 - 3.2e-13 49.8 0.0 5.3e-13 49.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS32470.1 - 2.6e-10 40.9 0.0 8e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS32470.1 - 5.3e-08 33.5 0.0 2.4e-06 28.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS32470.1 - 5.1e-05 23.1 0.0 0.00055 19.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS32470.1 - 0.00017 22.2 0.0 0.002 18.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 CDS32470.1 - 0.02 14.0 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent NNMT_PNMT_TEMT PF01234.17 CDS32470.1 - 0.041 13.1 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family RAD51_interact PF15696.5 CDS32471.1 - 4.5e-06 26.7 2.0 6.8e-06 26.1 0.2 2.3 2 0 0 2 2 2 1 RAD51 interacting motif MIP-T3_C PF17749.1 CDS32471.1 - 0.056 13.4 0.4 0.092 12.7 0.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region TMEM154 PF15102.6 CDS32472.1 - 0.0046 16.9 0.0 0.0052 16.7 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 CDS32472.1 - 0.023 14.5 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MSP1a PF11670.8 CDS32472.1 - 0.031 13.6 0.4 0.038 13.3 0.4 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3619 PF12279.8 CDS32472.1 - 0.033 14.5 0.1 0.048 14.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4051 PF13260.6 CDS32472.1 - 0.054 13.2 1.2 0.087 12.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Endomucin PF07010.12 CDS32472.1 - 0.058 13.4 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Endomucin LRR19-TM PF15176.6 CDS32472.1 - 0.063 13.3 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2207 PF09972.9 CDS32472.1 - 0.16 10.7 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAM219A PF15260.6 CDS32476.1 - 1.9e-10 41.2 0.3 2.1e-10 41.0 0.3 1.1 1 0 0 1 1 1 1 Protein family FAM219A DUF2844 PF11005.8 CDS32476.1 - 0.09 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) PAP2_3 PF14378.6 CDS32477.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily F-box_4 PF15966.5 CDS32477.1 - 0.041 13.8 0.5 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 F-box Ras PF00071.22 CDS32478.1 - 3.2e-54 182.9 0.0 3.7e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS32478.1 - 5.5e-32 110.5 0.0 7.6e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS32478.1 - 3.4e-12 46.1 0.0 4.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS32478.1 - 2.2e-06 27.2 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDS32478.1 - 1.9e-05 24.3 0.0 0.0004 20.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDS32478.1 - 0.00051 19.5 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CDS32478.1 - 0.0015 18.3 0.0 0.0079 16.0 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CDS32478.1 - 0.0019 18.2 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CDS32478.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 CDS32478.1 - 0.19 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ets PF00178.22 CDS32479.1 - 1.2e-20 73.7 2.6 2.8e-20 72.6 2.6 1.6 1 0 0 1 1 1 1 Ets-domain MRP-L27 PF09809.9 CDS32480.1 - 8.8e-09 35.2 0.1 3.6e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 rve PF00665.26 CDS32481.1 - 4e-23 81.9 0.0 7.1e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS32481.1 - 6.2e-17 61.4 1.1 1.4e-16 60.3 1.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS32481.1 - 8.1e-05 22.8 0.1 0.00021 21.5 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDS32481.1 - 9e-05 22.2 0.0 0.00029 20.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDS32481.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 DDE domain Pkinase PF00069.25 CDS32482.1 - 9.7e-79 264.4 0.0 1.1e-50 172.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32482.1 - 1.3e-26 93.4 0.0 6.5e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS32482.1 - 2.7e-05 23.1 0.1 0.00025 20.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 CDS32482.1 - 0.005 16.4 2.2 0.16 11.5 0.0 3.1 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.23 CDS32482.1 - 0.024 14.5 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CDS32482.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDS32483.1 - 1.8e-77 260.3 0.0 3.6e-47 160.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32483.1 - 3.9e-23 82.1 0.0 4.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDS32483.1 - 0.00083 19.3 0.0 0.041 13.8 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS32483.1 - 0.0084 14.9 0.1 0.022 13.5 0.0 1.7 2 1 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 CDS32483.1 - 0.015 14.9 0.2 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CDS32483.1 - 0.036 13.4 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like bPH_1 PF08000.11 CDS32483.1 - 0.11 12.6 0.1 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain Kdo PF06293.14 CDS32483.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_1 PF00130.22 CDS32483.1 - 0.18 11.7 1.2 0.45 10.5 1.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CDS32483.1 - 0.21 11.5 0.6 0.41 10.6 0.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-met PF12874.7 CDS32484.1 - 0.0057 17.0 3.4 0.029 14.7 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDS32484.1 - 0.039 14.4 1.5 0.039 14.4 1.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS32484.1 - 0.21 12.5 13.3 0.22 12.4 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.32 CDS32487.1 - 2.9e-37 126.0 14.4 6.3e-05 23.7 0.0 11.0 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32487.1 - 8.8e-18 64.4 0.0 0.0044 17.3 0.0 7.0 3 3 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 CDS32487.1 - 5.5e-05 22.9 0.2 0.003 17.4 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 CDS32487.1 - 6.9e-05 22.0 0.2 2.7 6.8 0.0 4.7 4 1 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CDS32487.1 - 0.013 15.0 0.0 0.34 10.4 0.0 2.9 2 1 1 3 3 3 0 PQQ-like domain PD40 PF07676.12 CDS32487.1 - 0.019 14.9 0.2 4.1 7.5 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 CDS32487.1 - 0.14 12.7 4.5 1.2 9.7 0.1 4.4 4 0 0 4 4 4 0 PQQ-like domain DPPIV_N PF00930.21 CDS32487.1 - 0.18 10.5 0.0 3.8 6.2 0.0 3.2 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region VD10_N PF08476.10 CDS32487.1 - 0.2 11.3 0.2 0.84 9.4 0.0 2.1 3 0 0 3 3 3 0 Viral D10 N-terminal Sugar_tr PF00083.24 CDS32490.1 - 1.4e-25 90.1 14.1 1.9e-25 89.7 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS32490.1 - 4.2e-11 42.4 31.5 1.9e-10 40.2 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL20 PF04544.12 CDS32490.1 - 0.023 15.1 2.6 0.067 13.6 2.6 1.8 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Histone_H2A_C PF16211.5 CDS32490.1 - 0.19 11.5 0.3 0.41 10.4 0.3 1.6 1 0 0 1 1 1 0 C-terminus of histone H2A Actin PF00022.19 CDS32491.1 - 8.5e-125 416.5 0.0 4.5e-124 414.2 0.0 1.8 1 1 0 1 1 1 1 Actin CBS PF00571.28 CDS32493.2 - 5.5e-31 106.8 4.4 1.9e-11 44.2 0.3 4.5 5 0 0 5 5 5 4 CBS domain Kinesin PF00225.23 CDS32495.2 - 6.5e-108 360.6 1.3 6.5e-108 360.6 1.3 2.9 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CDS32495.2 - 4.8e-25 88.2 5.2 6e-25 87.9 0.1 3.3 3 0 0 3 3 3 1 Microtubule binding FliJ PF02050.16 CDS32495.2 - 0.013 15.7 9.0 0.013 15.7 9.0 6.5 5 2 2 7 7 7 0 Flagellar FliJ protein SHE3 PF17078.5 CDS32495.2 - 0.015 15.0 1.1 0.015 15.0 1.1 5.6 4 1 1 6 6 6 0 SWI5-dependent HO expression protein 3 ANAPC16 PF17256.2 CDS32495.2 - 0.11 12.9 2.8 6.5 7.2 0.0 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, subunit 16 SecD-TM1 PF13721.6 CDS32495.2 - 7.9 7.0 16.1 2.4 8.6 0.6 4.4 2 2 2 4 4 4 0 SecD export protein N-terminal TM region CAMSAP_CKK PF08683.11 CDS32496.2 - 1.9e-51 173.2 0.2 6.2e-51 171.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule-binding calmodulin-regulated spectrin-associated HEM4 PF02602.15 CDS32497.1 - 6.4e-34 117.3 0.0 7.6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HcyBio PF01837.16 CDS32498.1 - 0.017 14.0 0.1 0.018 13.9 0.1 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation TAFII28 PF04719.14 CDS32499.1 - 1.1e-30 105.5 0.0 2e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Pox_Ag35 PF03286.14 CDS32499.1 - 1.6 8.5 6.0 2.5 7.8 6.0 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein zf-RING_2 PF13639.6 CDS32500.2 - 1.3e-10 41.4 7.8 3.6e-10 40.0 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDS32500.2 - 5.7e-07 29.7 8.4 1.6e-06 28.3 8.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS32500.2 - 1.8e-06 27.8 3.9 7.6e-06 25.8 3.9 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDS32500.2 - 4.5e-06 26.4 6.2 1.2e-05 25.0 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDS32500.2 - 1.8e-05 24.4 5.8 4.2e-05 23.2 5.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDS32500.2 - 5.8e-05 22.9 4.9 5.8e-05 22.9 4.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS32500.2 - 0.00028 20.9 2.4 0.0014 18.6 2.4 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDS32500.2 - 0.0015 18.3 8.4 0.0038 17.0 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDS32500.2 - 0.0015 18.1 10.9 0.0036 16.9 10.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDS32500.2 - 0.019 15.0 7.7 0.048 13.7 7.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CDS32500.2 - 1.4 9.1 7.5 4 7.7 7.5 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 CDS32500.2 - 2.9 7.8 11.9 0.28 11.1 6.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ACPS PF01648.20 CDS32501.2 - 4.3e-12 46.2 0.0 3e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily CTD_bind PF04818.13 CDS32502.1 - 5.5e-10 39.9 0.0 2.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF29 PF01724.16 CDS32502.1 - 0.03 14.6 0.5 0.084 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 DUF953 PF06110.11 CDS32504.2 - 5e-14 51.9 0.0 5.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) SNF2_N PF00176.23 CDS32505.1 - 2.7e-47 161.2 0.0 1.6e-33 115.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS32505.1 - 1.6e-13 51.0 0.0 1.5e-12 47.9 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS32505.1 - 7.6e-06 26.0 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PDZ PF00595.24 CDS32506.2 - 6.4e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS32506.2 - 3.1e-09 36.6 0.1 5.1e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS32506.2 - 8.5e-05 22.8 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain fragilysinNterm PF16376.5 CDS32506.2 - 0.066 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of fragilysin Mito_carr PF00153.27 CDS32507.1 - 3.9e-56 187.0 0.6 4.3e-21 74.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CDS32507.1 - 0.00011 21.4 2.2 0.0086 15.3 0.1 3.6 3 2 1 4 4 4 2 Gammaproteobacterial serine protease Pou PF00157.17 CDS32508.1 - 6.3e-29 99.8 0.1 2e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDS32508.1 - 2.8e-18 65.5 0.9 2.8e-18 65.5 0.9 1.7 2 0 0 2 2 2 1 Homeodomain HTH_31 PF13560.6 CDS32508.1 - 0.00019 21.7 0.0 0.0012 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 CDS32508.1 - 0.088 12.9 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix DENN PF02141.21 CDS32510.2 - 2.4e-33 115.7 5.4 9.8e-33 113.7 5.4 2.0 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CDS32510.2 - 4.4e-17 62.6 1.4 1.5e-16 60.8 1.4 2.1 1 0 0 1 1 1 1 uDENN domain SBF2 PF12335.8 CDS32510.2 - 0.056 13.1 0.3 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Myotubularin protein LMBR1 PF04791.16 CDS32511.2 - 1.3e-11 44.1 6.0 2.1e-11 43.5 6.0 1.4 1 0 0 1 1 1 1 LMBR1-like membrane protein GTP_EFTU PF00009.27 CDS32512.1 - 9.5e-56 188.4 0.0 1.8e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDS32512.1 - 4.6e-10 39.4 0.0 2.8e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CDS32512.1 - 0.0012 18.9 0.1 0.0037 17.3 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 CDS32512.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CDS32512.1 - 0.0023 18.0 0.0 0.0059 16.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase BUD22 PF09073.10 CDS32512.1 - 8.5 5.6 15.5 18 4.5 15.5 1.4 1 0 0 1 1 1 0 BUD22 DUF1731 PF08338.11 CDS32514.2 - 5.9e-19 67.6 0.8 1.1e-18 66.8 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 CDS32514.2 - 4.9e-08 32.7 0.0 0.0045 16.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDS32514.2 - 0.0066 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDS32514.2 - 0.068 12.6 0.0 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase EF-hand_1 PF00036.32 CDS32515.2 - 4.5e-19 66.5 1.5 9.1e-07 28.0 0.0 3.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDS32515.2 - 2.5e-17 63.1 0.3 4.9e-13 49.3 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS32515.2 - 1.3e-16 59.0 1.5 4.9e-06 26.1 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CDS32515.2 - 4e-14 52.2 1.2 3.1e-06 26.9 0.0 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS32515.2 - 1.5e-12 46.4 0.3 0.0002 20.7 0.0 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CDS32515.2 - 6.7e-06 26.4 0.2 0.1 12.9 0.0 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDS32515.2 - 3.9e-05 23.9 0.2 0.39 11.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDS32515.2 - 0.00018 21.4 0.9 0.015 15.2 0.1 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.11 CDS32515.2 - 0.00049 20.2 0.1 2.7 8.2 0.0 3.0 3 0 0 3 3 3 1 EF hand Dockerin_1 PF00404.18 CDS32515.2 - 0.00076 19.6 0.2 0.0018 18.4 0.2 1.6 1 1 0 1 1 1 1 Dockerin type I domain RST PF12174.8 CDS32515.2 - 0.0036 17.2 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain DUF3410 PF11890.8 CDS32515.2 - 0.036 13.9 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3410) C2 PF00168.30 CDS32516.1 - 8.2e-19 67.8 0.6 1.7e-11 44.3 0.4 2.6 2 1 0 2 2 2 2 C2 domain Prominin PF05478.11 CDS32516.1 - 0.028 12.4 1.4 0.041 11.9 1.4 1.2 1 0 0 1 1 1 0 Prominin SNX17_FERM_C PF18116.1 CDS32516.1 - 0.036 14.1 0.0 7 6.8 0.0 3.0 3 0 0 3 3 3 0 Sorting Nexin 17 FERM C-terminal domain TMEM52 PF14979.6 CDS32516.1 - 0.1 12.5 4.0 0.21 11.5 4.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 DUF4207 PF13904.6 CDS32517.1 - 3.7e-15 56.3 27.7 3.8e-15 56.3 27.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) SprA-related PF12118.8 CDS32517.1 - 0.98 8.5 14.2 1.2 8.2 14.2 1.1 1 0 0 1 1 1 0 SprA-related family G-patch PF01585.23 CDS32518.1 - 3.1e-14 52.6 0.9 5.4e-14 51.8 0.9 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS32518.1 - 0.00063 19.8 0.3 0.00063 19.8 0.3 2.4 3 0 0 3 3 3 1 G-patch domain Sec63 PF02889.16 CDS32519.1 - 6.2e-162 536.8 0.0 1.9e-87 292.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDS32519.1 - 9.4e-42 142.7 0.0 5.9e-23 81.5 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDS32519.1 - 1.1e-37 128.6 0.2 3.8e-37 126.9 0.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CDS32519.1 - 3.5e-19 69.5 0.0 3.4e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS32519.1 - 3.4e-10 40.2 0.0 1.3e-06 28.7 0.0 4.2 3 2 0 3 3 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDS32519.1 - 3.7e-05 24.0 0.0 0.33 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDS32519.1 - 0.00017 21.3 0.0 1.4 8.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 CDS32519.1 - 0.00097 18.6 0.0 0.29 10.6 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 CDS32519.1 - 0.0026 17.3 0.7 0.79 9.2 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CDS32519.1 - 0.011 14.8 0.0 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 CDS32519.1 - 0.022 15.1 0.0 14 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CDS32519.1 - 0.024 14.8 0.0 3 8.0 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDS32519.1 - 0.045 13.3 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDS32519.1 - 0.062 13.0 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 CDS32519.1 - 5.6 6.7 6.2 12 5.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain DnaJ_C PF01556.18 CDS32520.1 - 9.1e-28 97.2 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDS32520.1 - 3.2e-26 91.2 4.9 5.5e-26 90.5 4.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDS32520.1 - 3.6e-10 40.1 18.0 3.6e-10 40.1 18.0 1.9 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CDS32520.1 - 1.2 9.1 20.6 5.4 7.0 3.1 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf_CopZ PF18423.1 CDS32520.1 - 3 7.9 7.3 3.1 7.8 0.2 3.0 2 1 1 3 3 3 0 Zinc binding domain BCL_N PF04714.13 CDS32521.2 - 9.4e-14 51.2 10.7 5e-08 32.9 3.6 2.3 2 0 0 2 2 2 2 BCL7, N-terminal conserver region DJ-1_PfpI PF01965.24 CDS32522.2 - 6.8e-06 26.0 0.1 2.1e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family cNMP_binding PF00027.29 CDS32524.1 - 1.7e-40 136.9 0.0 1.8e-20 72.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CDS32524.1 - 1.8e-08 33.9 0.0 4.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit LRR_8 PF13855.6 CDS32525.1 - 3.3e-12 46.0 12.2 6e-09 35.5 3.5 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_5 PF13306.6 CDS32525.1 - 2.4e-05 24.3 0.1 6.6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDS32525.1 - 4.3e-05 23.8 14.9 0.0049 17.2 0.3 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS32525.1 - 4.5e-05 23.0 0.4 0.00019 21.0 0.4 1.9 1 1 1 2 2 2 1 Leucine-rich repeat ig PF00047.25 CDS32525.1 - 6.1e-05 23.1 0.1 0.00033 20.8 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain LRR_1 PF00560.33 CDS32525.1 - 0.0014 18.9 13.2 0.56 11.0 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat I-set PF07679.16 CDS32525.1 - 0.0017 18.4 0.1 0.0046 17.0 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS32525.1 - 0.018 15.6 0.0 0.079 13.6 0.0 2.1 1 0 0 1 1 1 0 Immunoglobulin domain LRR_6 PF13516.6 CDS32525.1 - 2.2 8.6 9.3 17 5.8 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 CDS32527.1 - 0.0018 18.6 17.3 5 7.7 0.2 6.6 3 2 3 7 7 7 4 Leucine Rich repeats (2 copies) Ribosomal_L22e PF01776.17 CDS32527.1 - 0.12 12.8 0.2 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L22e protein family EMC3_TMCO1 PF01956.16 CDS32528.1 - 7e-47 159.3 0.4 1e-46 158.8 0.4 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PWWP PF00855.17 CDS32529.1 - 4.4e-10 39.8 0.2 8.3e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 PWWP domain PH PF00169.29 CDS32530.1 - 1.3e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PH domain RA PF00788.23 CDS32530.1 - 0.0014 19.2 0.2 0.0036 17.9 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Cytochrom_C1 PF02167.15 CDS32530.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family DUF3022 PF11226.8 CDS32530.1 - 0.12 12.8 0.4 0.34 11.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) AAA_2 PF07724.14 CDS32531.1 - 8.9e-40 136.6 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDS32531.1 - 4.4e-13 49.8 0.0 8.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDS32531.1 - 4.2e-11 42.7 0.1 8.4e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDS32531.1 - 1.4e-05 25.1 0.0 5.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDS32531.1 - 2.3e-05 23.9 0.1 0.033 13.6 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CDS32531.1 - 4.9e-05 23.1 0.0 0.00027 20.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 CDS32531.1 - 7.8e-05 23.0 0.1 0.00029 21.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDS32531.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDS32531.1 - 0.0059 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CDS32531.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDS32531.1 - 0.014 15.8 0.1 0.056 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CDS32531.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DEAD PF00270.29 CDS32531.1 - 0.02 14.7 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.6 CDS32531.1 - 0.021 14.9 0.0 0.057 13.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 CDS32531.1 - 0.025 14.3 0.1 0.1 12.3 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF4727 PF15856.5 CDS32531.1 - 0.028 14.0 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) TsaE PF02367.17 CDS32531.1 - 0.033 14.2 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDS32531.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CDS32531.1 - 0.051 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Nudix_N_2 PF14803.6 CDS32531.1 - 0.064 13.2 3.4 0.13 12.2 0.6 2.3 2 0 0 2 2 2 0 Nudix N-terminal AAA_29 PF13555.6 CDS32531.1 - 0.074 12.8 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDS32531.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CDS32531.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain C1_1 PF00130.22 CDS32531.1 - 0.084 12.8 0.5 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FtsK_SpoIIIE PF01580.18 CDS32531.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DZR PF12773.7 CDS32531.1 - 0.16 12.0 1.2 0.79 9.8 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon PduV-EutP PF10662.9 CDS32531.1 - 0.22 11.3 0.1 0.54 10.0 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RRM_7 PF16367.5 CDS32532.1 - 4.7e-26 90.7 0.0 2e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 CDS32532.1 - 8.7e-21 73.9 5.5 1.6e-20 73.1 4.6 1.9 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CDS32532.1 - 8.2e-09 35.2 0.0 0.023 14.5 0.0 3.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDS32532.1 - 0.0028 17.6 0.0 0.0095 15.9 0.0 1.9 1 0 0 1 1 1 1 RNA binding domain Vps16_N PF04841.13 CDS32533.1 - 2e-49 168.5 0.0 6.4e-49 166.8 0.0 1.8 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CDS32533.1 - 6.5e-37 127.3 2.5 5.9e-20 71.6 0.9 2.6 2 1 0 2 2 2 2 Vps16, C-terminal region TFIIIC_delta PF12657.7 CDS32533.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term tRNA_U5-meth_tr PF05958.11 CDS32534.1 - 3.5e-11 42.7 0.0 9.9e-11 41.2 0.0 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CDS32534.1 - 4.1e-10 39.6 0.1 9.3e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS32534.1 - 1.4e-07 32.1 0.2 6.8e-07 29.9 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CDS32534.1 - 7.9e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CDS32534.1 - 9.8e-06 25.2 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDS32534.1 - 3.9e-05 23.2 0.2 7.1e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CDS32534.1 - 0.00047 19.8 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AviRa PF11599.8 CDS32534.1 - 0.00089 18.8 0.9 0.0097 15.4 0.4 2.3 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 CDS32534.1 - 0.002 18.7 0.1 0.01 16.4 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain PCMT PF01135.19 CDS32534.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CDS32534.1 - 0.0052 16.1 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CDS32534.1 - 0.017 14.6 0.2 0.034 13.6 0.2 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 CDS32534.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDS32534.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 CDS32534.1 - 0.15 11.9 0.0 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_65C PF03633.15 CDS32534.1 - 0.28 11.1 0.7 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain LRR_4 PF12799.7 CDS32535.2 - 0.058 13.8 18.0 3.2 8.3 2.5 5.9 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS32535.2 - 0.1 12.4 5.4 2.9 7.7 0.9 3.9 3 1 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 CDS32535.2 - 2.8 8.2 7.5 27 5.1 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 CDS32536.1 - 2.9 8.5 16.2 7.4 7.1 1.3 5.4 3 2 5 8 8 8 0 Leucine Rich repeats (2 copies) Sina PF03145.16 CDS32537.1 - 8.8e-77 257.6 0.1 1.3e-76 257.0 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 CDS32537.1 - 0.02 14.7 11.0 0.085 12.7 11.0 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 CDS32537.1 - 0.17 12.3 10.4 16 6.0 2.8 3.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CDS32537.1 - 4.3 7.4 16.2 3.2 7.8 12.5 2.8 2 1 1 3 3 3 0 zinc-RING finger domain AA_permease_2 PF13520.6 CDS32538.1 - 1.5e-58 198.6 46.9 2e-58 198.3 46.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS32538.1 - 1.6e-22 79.8 43.1 2e-22 79.5 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease F-box PF00646.33 CDS32539.1 - 7.8e-09 35.2 0.1 1.4e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDS32539.1 - 0.0001 22.1 0.1 0.00014 21.6 0.1 1.2 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CDS32539.1 - 0.007 16.2 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 F-box AA_permease_2 PF13520.6 CDS32540.1 - 1.9e-58 198.3 47.5 2.5e-58 197.9 47.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS32540.1 - 1.8e-25 89.5 42.8 2.4e-25 89.1 42.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDS32541.1 - 5.9e-60 203.3 46.3 7e-60 203.0 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDS32541.1 - 1.3e-26 93.3 41.4 1.8e-26 92.8 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S3Ae PF01015.18 CDS32542.1 - 8.2e-84 280.2 1.7 1e-83 279.9 1.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CDS32542.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Med26_C PF15693.5 CDS32542.1 - 0.071 13.3 0.4 5 7.2 0.1 2.1 1 1 1 2 2 2 0 Mediator complex subunit 26 C-terminal CD36 PF01130.21 CDS32543.1 - 1.2e-117 393.3 1.8 1.6e-117 392.9 1.8 1.0 1 0 0 1 1 1 1 CD36 family Taxilin PF09728.9 CDS32544.1 - 8.6e-05 21.9 6.4 8.6e-05 21.9 6.4 2.5 2 1 0 2 2 2 1 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 CDS32544.1 - 0.011 15.7 13.1 0.011 15.7 13.1 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT20 PF14931.6 CDS32544.1 - 0.015 15.4 13.9 0.59 10.3 7.6 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 MPS2 PF17060.5 CDS32544.1 - 0.035 13.4 8.6 0.085 12.1 8.5 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 YabA PF06156.13 CDS32544.1 - 0.041 14.5 0.5 0.041 14.5 0.5 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 CDS32544.1 - 0.67 9.7 15.1 0.14 12.0 5.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 CDS32544.1 - 0.76 9.9 21.7 0.023 14.8 12.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 CDS32544.1 - 2.2 8.7 17.7 0.45 11.0 1.4 2.3 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 CDS32544.1 - 4.9 7.3 16.4 2.8 8.1 4.3 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TBCA PF02970.16 CDS32544.1 - 5 7.5 16.1 1.1 9.7 10.1 2.5 2 0 0 2 2 2 0 Tubulin binding cofactor A ADIP PF11559.8 CDS32544.1 - 9.1 6.3 20.1 0.074 13.1 5.6 3.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Nt_Gln_amidase PF09764.9 CDS32545.1 - 6.9e-41 139.9 0.0 8.2e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase Pkinase PF00069.25 CDS32546.1 - 3.9e-34 118.2 0.0 4.9e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32546.1 - 2.9e-16 59.5 0.0 4.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32546.1 - 4.2e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS32546.1 - 0.0021 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LIM PF00412.22 CDS32547.1 - 8.7e-23 80.3 15.5 1.7e-11 44.2 0.7 2.4 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDS32547.1 - 1e-14 54.1 0.1 1.6e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32547.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-FLZ PF04570.14 CDS32547.1 - 8.4 6.0 17.2 9.1 5.8 0.3 3.9 3 1 1 4 4 4 0 zinc-finger of the FCS-type, C2-C2 YEATS PF03366.16 CDS32548.1 - 4.8e-30 103.4 0.4 8e-30 102.6 0.4 1.4 1 0 0 1 1 1 1 YEATS family LPD13 PF18825.1 CDS32548.1 - 0.035 13.9 0.6 0.07 12.9 0.6 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 RrnaAD PF00398.20 CDS32551.2 - 8.5e-38 129.9 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CDS32551.2 - 0.0038 17.9 0.0 0.0064 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PELOTA_1 PF15608.6 CDS32551.2 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain Methyltransf_23 PF13489.6 CDS32551.2 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AIP3 PF03915.13 CDS32552.2 - 1.1e-09 37.9 3.2 7.6e-08 31.9 1.2 2.4 2 0 0 2 2 2 2 Actin interacting protein 3 DUF1168 PF06658.12 CDS32553.1 - 2.7e-28 98.5 24.4 9.2e-27 93.5 24.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) DUF2229 PF09989.9 CDS32553.1 - 0.014 15.1 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PPL5 PF18168.1 CDS32553.1 - 0.48 9.7 5.8 0.59 9.4 5.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Afi1 PF07792.12 CDS32553.1 - 0.77 10.2 6.0 1.2 9.6 6.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF755 PF05501.11 CDS32553.1 - 1.1 9.6 14.2 1.7 8.9 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MMM1 PF10296.9 CDS32553.1 - 1.4 7.8 5.9 2 7.4 5.9 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 CBFB_NFYA PF02045.15 CDS32553.1 - 6.3 7.5 14.0 14 6.4 14.0 1.5 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Sdh5 PF03937.16 CDS32554.1 - 3.4e-25 87.8 0.2 4.4e-25 87.4 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase 7tm_1 PF00001.21 CDS32555.1 - 1.2e-22 80.6 18.9 1.8e-22 79.9 18.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS32555.1 - 0.00022 20.9 15.3 0.00022 20.9 15.3 2.6 3 1 1 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srx RRM_7 PF16367.5 CDS32556.1 - 2e-36 124.0 0.0 5.7e-35 119.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif CEBP_ZZ PF16366.5 CDS32556.1 - 9.3e-20 70.6 6.2 9.3e-20 70.6 6.2 2.5 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RRM_1 PF00076.22 CDS32556.1 - 3.1e-10 39.7 0.0 1e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.24 CDS32556.1 - 0.34 11.1 7.3 0.75 10.0 7.3 1.5 1 0 0 1 1 1 0 B-box zinc finger Exo_endo_phos_2 PF14529.6 CDS32557.1 - 0.068 13.0 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Polysacc_synt_4 PF04669.13 CDS32560.1 - 3e-17 62.8 0.0 4.2e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA PF00004.29 CDS32561.1 - 2.6e-14 53.8 0.1 7.6e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 CDS32561.1 - 6.8e-07 28.5 0.5 6.8e-07 28.5 0.5 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 CDS32561.1 - 0.053 13.8 0.2 0.81 10.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain UPF0565 PF10561.9 CDS32562.1 - 1e-33 116.9 0.0 2.5e-16 59.8 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 dsrm PF00035.26 CDS32564.2 - 1.5e-19 70.5 2.9 2.8e-06 27.9 0.2 5.8 5 2 0 5 5 5 3 Double-stranded RNA binding motif MCR_alpha PF02249.17 CDS32564.2 - 2.3e-05 24.8 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Dicer_dimer PF03368.14 CDS32564.2 - 0.0017 18.5 0.1 18 5.6 0.0 3.7 3 0 0 3 3 3 2 Dicer dimerisation domain DND1_DSRM PF14709.7 CDS32564.2 - 0.0026 18.0 7.5 16 5.9 0.2 5.9 5 2 0 5 5 5 2 double strand RNA binding domain from DEAD END PROTEIN 1 TTL PF03133.15 CDS32565.1 - 5.2e-77 258.9 0.1 8.6e-77 258.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDS32565.1 - 1.4e-07 31.0 0.0 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDS32565.1 - 0.0018 17.6 0.0 0.041 13.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp FliJ PF02050.16 CDS32565.1 - 0.089 13.0 2.9 0.37 11.0 0.8 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein NACHT_N PF17100.5 CDS32565.1 - 0.18 11.7 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase WH1 PF00568.23 CDS32566.1 - 4.6e-24 84.5 0.2 6.4e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 WH1 domain CSRNP_N PF16019.5 CDS32566.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus HLH PF00010.26 CDS32567.1 - 1.7e-13 50.3 2.0 1.7e-13 50.3 2.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GM_CSF PF01109.17 CDS32567.1 - 0.0076 16.4 0.0 0.066 13.4 0.0 2.5 2 0 0 2 2 2 1 Granulocyte-macrophage colony-stimulating factor zf-C4 PF00105.18 CDS32568.1 - 1.2e-32 112.2 13.6 2.1e-32 111.4 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS32568.1 - 1.2e-14 54.4 0.3 3.2e-14 53.0 0.3 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PAN_3 PF08277.12 CDS32568.1 - 0.1 12.4 1.4 0.28 11.0 1.4 1.7 1 0 0 1 1 1 0 PAN-like domain TRAP_beta PF05753.14 CDS32569.1 - 4.5e-42 143.4 0.0 5.4e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) BatD PF13584.6 CDS32569.1 - 0.00022 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Oxygen tolerance DUF4603 PF15376.6 CDS32569.1 - 0.11 9.8 0.0 0.14 9.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RRM_1 PF00076.22 CDS32570.1 - 0.00051 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDS32570.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RL domain Peptidase_C1 PF00112.23 CDS32572.1 - 4.1e-80 268.9 9.8 5.2e-80 268.6 9.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDS32572.1 - 3.7e-14 52.9 2.8 6.7e-14 52.1 2.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDS32572.1 - 2.3e-06 26.7 3.5 0.00038 19.4 1.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Isochorismatase PF00857.20 CDS32573.1 - 1.2e-25 90.7 0.1 2.1e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Isochorismatase family SH3_9 PF14604.6 CDS32573.1 - 1.2e-10 41.1 0.0 6.8e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CDS32573.1 - 2.2e-10 40.0 0.0 2.2e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CDS32573.1 - 1e-08 34.7 0.0 2.2e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 CDS32573.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 2 0 Helically-extended SH3 domain TAP_C PF03943.13 CDS32574.1 - 7.7e-15 54.3 0.1 1.9e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 CDS32574.1 - 0.0001 22.0 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain DPM3 PF08285.11 CDS32575.1 - 3.3e-22 78.5 0.0 3.6e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Isochorismatase PF00857.20 CDS32577.1 - 1.4e-25 90.4 0.1 2.6e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Isochorismatase family SH2 PF00017.24 CDS32577.1 - 2.1e-16 59.7 0.1 5.3e-16 58.5 0.1 1.7 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.6 CDS32577.1 - 1.4e-10 40.9 0.0 7.8e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CDS32577.1 - 2.3e-10 39.9 0.0 2.6e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CDS32577.1 - 1.3e-08 34.3 0.0 2.6e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 CDS32577.1 - 0.16 12.4 0.0 0.48 10.9 0.0 1.8 2 0 0 2 2 2 0 Helically-extended SH3 domain DOCK-C2 PF14429.6 CDS32578.1 - 9.2e-22 77.8 0.0 8.4e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 CDS32578.1 - 1.1e-13 50.7 1.1 7.1e-13 48.0 0.0 2.5 2 1 0 2 2 2 1 Dock homology region 2 Mannosyl_trans2 PF04188.13 CDS32579.1 - 1.5e-43 149.8 20.8 1.8e-43 149.5 20.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) HlyIII PF03006.20 CDS32580.1 - 9.9e-66 221.6 24.3 1.2e-65 221.4 24.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 CDS32580.1 - 3.4 7.8 7.6 0.14 12.3 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Peptidase_M48_N PF16491.5 CDS32581.1 - 9.7e-62 208.1 7.2 9.7e-62 208.1 7.2 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDS32581.1 - 6.5e-39 133.7 0.0 1.3e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Maf PF02545.14 CDS32581.1 - 3.5e-37 127.8 0.0 1e-36 126.3 0.0 1.7 2 0 0 2 2 2 1 Maf-like protein Sugar_tr PF00083.24 CDS32584.1 - 9e-22 77.5 22.2 3.5e-21 75.6 22.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS32584.1 - 4e-15 55.6 26.0 4.1e-15 55.6 22.9 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Maf PF02545.14 CDS32586.1 - 1.5e-52 177.8 0.0 1.8e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein FAM220 PF15487.6 CDS32599.1 - 0.31 10.6 3.1 0.28 10.8 0.9 1.8 2 0 0 2 2 2 0 FAM220 family AAA_lid_3 PF17862.1 CDS32600.1 - 0.00032 20.5 0.1 0.00047 19.9 0.1 1.2 1 0 0 1 1 1 1 AAA+ lid domain BTB PF00651.31 CDS32601.1 - 5.4e-09 36.3 0.0 1.2e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF5122 PF17164.4 CDS32601.1 - 0.12 12.7 1.5 27 5.2 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Myb_DNA-binding PF00249.31 CDS32602.1 - 0.097 12.9 0.1 0.097 12.9 0.1 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain fn3 PF00041.21 CDS32603.2 - 5.7e-256 827.8 71.1 8.6e-16 58.1 0.1 36.4 36 1 0 36 36 35 31 Fibronectin type III domain I-set PF07679.16 CDS32603.2 - 5.9e-177 574.3 0.0 9.4e-15 54.5 0.0 20.2 19 0 0 19 19 19 18 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS32603.2 - 8.8e-124 404.4 10.1 4.4e-11 43.2 0.1 20.1 19 1 0 19 19 18 17 Immunoglobulin domain ig PF00047.25 CDS32603.2 - 3.2e-64 213.1 0.9 9.3e-07 28.9 0.0 16.6 16 0 0 16 16 16 10 Immunoglobulin domain Ig_2 PF13895.6 CDS32603.2 - 9.8e-50 166.8 0.7 8e-09 35.7 0.1 15.0 15 0 0 15 15 14 8 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDS32603.2 - 2.1e-36 124.4 32.4 0.0075 16.8 0.0 23.8 28 2 0 28 28 23 8 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CDS32603.2 - 1.4e-33 115.4 4.2 0.0019 18.3 0.1 16.2 17 1 0 17 17 15 8 Immunoglobulin V-set domain Pkinase PF00069.25 CDS32603.2 - 7.9e-22 77.9 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Tissue_fac PF01108.17 CDS32603.2 - 2e-20 72.7 2.0 0.0021 17.9 0.0 12.8 12 0 0 12 12 12 3 Tissue factor DUF2369 PF10179.9 CDS32603.2 - 6.9e-12 45.6 0.0 14 6.1 0.0 11.2 12 0 0 12 12 11 0 Uncharacterised conserved protein (DUF2369) PhoD_N PF16655.5 CDS32603.2 - 1.9e-09 37.9 2.3 16 6.2 0.0 10.8 13 0 0 13 13 9 0 PhoD-like phosphatase, N-terminal domain Receptor_2B4 PF11465.8 CDS32603.2 - 7.3e-09 35.8 0.0 1.3 9.3 0.0 9.0 10 0 0 10 10 10 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CDS32603.2 - 2.7e-07 30.6 14.5 0.013 15.5 0.0 9.5 13 0 0 13 13 11 1 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.10 CDS32603.2 - 1.6e-06 28.4 0.0 12 6.3 0.0 9.3 12 0 0 12 12 9 0 Interferon-alpha/beta receptor, fibronectin type III BiPBP_C PF06832.12 CDS32603.2 - 7.7e-06 25.9 0.0 0.82 9.8 0.0 6.6 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family Y_Y_Y PF07495.13 CDS32603.2 - 1.4e-05 24.9 8.0 39 4.3 0.0 11.8 16 0 0 16 16 11 0 Y_Y_Y domain Pkinase_Tyr PF07714.17 CDS32603.2 - 1.5e-05 24.4 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1-set PF07654.15 CDS32603.2 - 0.00019 21.7 0.0 55 4.2 0.0 6.5 7 0 0 7 7 5 0 Immunoglobulin C1-set domain Kinase-like PF14531.6 CDS32603.2 - 0.00096 18.5 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Izumo-Ig PF16706.5 CDS32603.2 - 0.003 17.6 4.5 27 4.9 0.0 7.9 10 0 0 10 10 9 0 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 CDS32603.2 - 0.0094 15.5 1.6 1.6 8.4 0.0 4.0 3 0 0 3 3 3 1 Immunoglobulin domain Kelch_1 PF01344.25 CDS32603.2 - 0.32 10.6 8.8 44 3.8 0.0 5.4 5 0 0 5 5 5 0 Kelch motif Herpes_gE PF02480.16 CDS32603.2 - 0.53 9.0 10.1 23 3.6 0.1 6.1 8 1 1 9 9 9 0 Alphaherpesvirus glycoprotein E Mito_carr PF00153.27 CDS32604.1 - 2.1e-31 107.7 0.0 1.4e-20 72.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CDS32605.1 - 4e-16 58.7 1.2 6.1e-14 51.7 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein TRIC PF05197.13 CDS32606.1 - 7.2e-81 270.4 4.2 1.5e-59 200.8 1.4 2.3 2 0 0 2 2 2 2 TRIC channel TED_complement PF07678.14 CDS32607.1 - 1.3e-17 63.8 0.0 1e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 A-macroglobulin TED domain A2M_recep PF07677.14 CDS32607.1 - 5.2e-16 59.1 0.2 1.2e-15 57.9 0.2 1.7 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain RNase_H PF00075.24 CDS32608.1 - 0.00023 21.4 0.0 0.00062 20.0 0.0 1.8 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDS32608.1 - 0.037 14.7 2.9 0.081 13.7 2.9 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase PIH1 PF08190.12 CDS32609.1 - 6.2e-20 71.3 0.0 9.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CDS32609.1 - 8.7e-13 48.5 0.0 3.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 PIH1 CS-like domain Cbl_N PF02262.16 CDS32610.1 - 1.4e-46 157.6 1.1 3.4e-46 156.3 1.1 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.14 CDS32610.1 - 4.2e-40 135.5 0.0 7.5e-40 134.7 0.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 CDS32610.1 - 4.1e-32 110.7 1.7 8.3e-32 109.8 1.7 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Prok-RING_4 PF14447.6 CDS32610.1 - 2.6e-12 46.4 9.0 5.1e-12 45.5 9.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDS32610.1 - 2.7e-10 39.9 10.0 5e-10 39.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS32610.1 - 8.4e-07 28.8 13.4 1.6e-06 27.9 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS32610.1 - 1.8e-05 24.6 11.8 3.7e-05 23.6 11.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDS32610.1 - 2.2e-05 24.7 11.4 4.3e-05 23.8 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDS32610.1 - 0.0025 17.8 11.9 0.0053 16.7 11.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS32610.1 - 0.0036 17.1 11.4 0.0064 16.3 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HAUS4 PF14735.6 CDS32610.1 - 0.11 12.2 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 zf-RING_4 PF14570.6 CDS32610.1 - 1.1 9.2 8.3 2.4 8.0 8.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CDS32610.1 - 1.6 8.7 5.8 4.7 7.1 5.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CDS32610.1 - 3.8 7.7 11.6 8.2 6.7 11.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING COPI_C PF06957.11 CDS32611.1 - 1e-137 459.2 0.0 1.2e-137 458.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CDS32611.1 - 2.8e-116 389.2 0.1 7.7e-116 387.7 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CDS32611.1 - 3.1e-40 135.4 18.3 5.6e-07 30.2 0.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32611.1 - 6e-08 32.9 0.1 0.0026 18.0 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS32611.1 - 0.00091 18.0 6.1 0.051 12.2 0.1 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Med1 PF10744.9 CDS32612.1 - 4.9e-11 42.3 1.4 1.4e-10 40.8 0.0 2.4 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 ASC PF00858.24 CDS32613.1 - 4.4e-08 32.5 0.1 4.4e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 CDS32614.1 - 6.3e-14 51.8 6.0 1.2e-13 50.9 6.0 1.4 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel Ribosomal_S7 PF00177.21 CDS32615.1 - 4.3e-29 101.1 1.4 5.1e-29 100.8 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 CDS32616.1 - 9.9e-56 188.4 0.0 1.4e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDS32616.1 - 5.5e-25 87.3 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDS32616.1 - 2.2e-11 43.6 0.0 1.1e-10 41.4 0.0 2.2 2 1 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDS32616.1 - 2.4e-07 31.0 0.0 7.8e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDS32616.1 - 2.8e-06 27.2 0.0 5.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CDS32616.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ODV-E18 PF10717.9 CDS32617.1 - 0.032 14.1 1.4 0.061 13.2 0.1 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Insulin_TMD PF17870.1 CDS32617.1 - 0.6 10.2 3.0 1.2 9.2 3.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HECT PF00632.25 CDS32618.1 - 3.7e-89 299.2 0.0 5.4e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 CDS32618.1 - 6.6e-67 222.0 30.0 3.5e-11 43.5 2.1 8.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDS32618.1 - 7.9e-39 130.7 31.2 7.3e-08 32.0 0.0 8.4 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 CDS32618.1 - 0.0053 17.0 0.2 6.5 7.2 0.0 4.0 5 0 0 5 5 5 2 Kelch motif Ribosomal_L13 PF00572.18 CDS32619.1 - 6.5e-12 45.8 0.1 5.4e-10 39.6 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 AMPK1_CBM PF16561.5 CDS32620.1 - 3.9e-34 116.7 1.0 6.6e-34 116.0 1.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CDS32620.1 - 2.2e-25 88.7 1.1 4.5e-25 87.7 1.1 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 CDS32620.1 - 0.0008 19.9 0.1 0.0014 19.1 0.1 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 CDS32620.1 - 0.013 15.8 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3800 PF12686.7 CDS32621.1 - 0.0037 17.9 0.0 6.2 7.5 0.0 4.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) IQ PF00612.27 CDS32621.1 - 0.051 13.4 3.1 0.18 11.7 3.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif SAB PF04382.13 CDS32621.1 - 0.097 12.8 3.8 0.39 10.8 0.2 3.2 2 0 0 2 2 2 0 SAB domain DIX PF00778.17 CDS32622.1 - 3.6e-31 106.8 0.0 4.2e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 DIX domain EPL1 PF10513.9 CDS32622.1 - 0.21 12.0 0.0 0.29 11.5 0.0 1.3 1 1 0 1 1 1 0 Enhancer of polycomb-like Dishevelled PF02377.15 CDS32623.2 - 1.7e-26 93.6 18.8 1.7e-26 93.6 18.8 4.3 4 1 0 4 4 4 1 Dishevelled specific domain PDZ PF00595.24 CDS32623.2 - 4.5e-19 68.6 0.7 1.1e-18 67.3 0.7 1.7 1 0 0 1 1 1 1 PDZ domain DEP PF00610.21 CDS32623.2 - 6.6e-13 48.5 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_6 PF17820.1 CDS32623.2 - 2e-06 27.6 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS32623.2 - 0.0016 18.7 0.2 0.0034 17.7 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Spt20 PF12090.8 CDS32623.2 - 0.0082 15.8 2.2 0.0082 15.8 2.2 2.5 3 0 0 3 3 3 1 Spt20 family Suf PF05843.14 CDS32623.2 - 1 9.3 3.9 0.32 10.9 0.2 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Amidinotransf PF02274.17 CDS32624.1 - 3.7e-11 42.7 0.3 1e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Amidinotransferase Pkinase PF00069.25 CDS32625.1 - 1.7e-66 224.3 0.0 2.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32625.1 - 1e-47 162.6 0.0 1.4e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS32625.1 - 1.9e-06 26.9 0.0 3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDS32625.1 - 0.00047 19.2 0.0 0.002 17.1 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS32625.1 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDS32625.1 - 0.051 12.9 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 CDS32626.1 - 8.5e-32 109.6 1.5 3.8e-13 49.8 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32626.1 - 5.3e-21 74.7 6.9 2.9e-07 30.9 0.1 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32626.1 - 2.2e-20 70.6 5.8 4.1e-05 23.6 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CDS32626.1 - 6.2e-18 64.6 2.9 5.3e-05 23.4 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CDS32626.1 - 2.8e-15 56.0 7.6 2e-05 24.8 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat HEAT_2 PF13646.6 CDS32628.1 - 5.9e-05 23.4 2.9 0.22 11.9 0.1 3.3 3 0 0 3 3 3 2 HEAT repeats SOGA PF11365.8 CDS32628.1 - 0.0074 17.4 0.6 0.0074 17.4 0.6 3.5 3 0 0 3 3 3 1 Protein SOGA HEAT PF02985.22 CDS32628.1 - 0.058 13.7 6.1 3.5 8.2 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat GAS PF13851.6 CDS32628.1 - 0.94 8.8 9.7 1.2 8.5 4.9 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 CDS32628.1 - 7.9 6.8 6.8 9.8 6.5 0.5 2.9 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Pkinase PF00069.25 CDS32629.1 - 5.2e-69 232.5 0.0 7.5e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32629.1 - 4.1e-44 150.8 0.0 6.3e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDS32629.1 - 1.9e-16 60.1 0.0 7.3e-16 58.3 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CDS32629.1 - 2.5e-05 23.8 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDS32629.1 - 2.9e-05 23.1 1.3 0.00025 19.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDS32629.1 - 0.034 13.5 0.4 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORC3_N PF07034.11 CDS32630.1 - 1.7e-23 83.3 0.2 3e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CDS32630.1 - 9.6e-16 58.1 0.1 2.9e-07 30.7 0.1 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal Ank_2 PF12796.7 CDS32631.1 - 7.9e-37 125.7 0.9 3.3e-10 40.4 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32631.1 - 1.7e-31 108.2 0.5 2.7e-08 34.2 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32631.1 - 6.9e-26 87.5 0.4 0.0013 19.1 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 CDS32631.1 - 1.3e-22 79.2 1.1 0.00077 19.8 0.1 7.4 6 1 2 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 CDS32631.1 - 3e-22 78.4 5.2 2.4e-05 24.5 0.1 6.5 1 1 6 7 7 7 6 Ankyrin repeats (many copies) MAM33 PF02330.16 CDS32631.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein Ank_2 PF12796.7 CDS32632.1 - 7.4e-27 93.8 4.4 3.1e-09 37.3 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32632.1 - 3.8e-19 68.8 7.6 5.7e-06 26.8 0.1 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32632.1 - 9e-18 62.5 10.5 0.00017 21.7 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CDS32632.1 - 4.5e-17 61.7 11.5 3e-05 24.2 0.6 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CDS32632.1 - 1.1e-15 57.4 7.9 1.6e-06 28.2 0.4 5.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS32633.1 - 7.9e-29 100.1 0.3 7.5e-08 32.9 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32633.1 - 9.6e-22 77.1 0.3 4.5e-05 23.9 0.1 4.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS32633.1 - 9e-20 70.5 1.5 2.5e-06 27.6 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32633.1 - 6.1e-17 60.0 1.9 0.016 15.6 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 CDS32633.1 - 1.3e-16 60.2 2.4 7.6e-05 23.0 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 CDS32634.1 - 1.6e-27 95.9 8.5 4.7e-10 39.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS32634.1 - 3e-18 64.0 10.5 0.0039 17.6 0.1 7.3 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CDS32634.1 - 4.5e-17 62.2 4.9 0.00072 20.1 0.2 4.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS32634.1 - 2.4e-16 59.4 11.2 0.00083 19.7 0.1 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDS32634.1 - 3e-15 56.1 7.4 0.00011 22.4 0.1 5.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) TAFII55_N PF04658.13 CDS32636.1 - 0.064 13.0 0.1 0.071 12.8 0.1 1.0 1 0 0 1 1 1 0 TAFII55 protein conserved region GPR15L PF15854.5 CDS32636.1 - 0.094 13.0 0.8 0.11 12.8 0.8 1.4 1 1 0 1 1 1 0 G-protein coupled receptor ligand 15 FAD_binding_2 PF00890.24 CDS32637.1 - 1e-126 423.4 0.8 1.4e-126 423.0 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CDS32637.1 - 1.3e-39 135.1 0.0 1.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CDS32637.1 - 1.4e-05 24.5 0.7 0.00062 19.1 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDS32637.1 - 2e-05 24.0 0.5 0.038 13.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CDS32637.1 - 2.7e-05 23.5 0.5 0.023 13.8 1.2 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 CDS32637.1 - 0.0051 15.6 0.7 0.72 8.5 0.2 2.5 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 CDS32637.1 - 0.014 14.7 0.2 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CDS32638.1 - 9.2e-18 64.6 0.1 2e-09 37.1 0.0 2.5 3 1 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 CDS32638.1 - 0.2 10.8 0.0 0.4 9.9 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase I-set PF07679.16 CDS32639.1 - 0 1243.5 0.0 4.8e-17 61.8 0.0 28.6 28 0 0 28 28 28 28 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS32639.1 - 0 1180.4 36.8 6.4e-15 55.5 0.1 28.7 28 0 0 28 28 28 28 Immunoglobulin domain Ig_2 PF13895.6 CDS32639.1 - 7.6e-243 785.6 21.6 1.2e-11 44.7 0.0 29.6 28 1 0 28 28 28 28 Immunoglobulin domain ig PF00047.25 CDS32639.1 - 4.2e-216 699.9 13.7 6.4e-10 39.1 0.0 29.4 28 1 0 28 28 28 28 Immunoglobulin domain V-set PF07686.17 CDS32639.1 - 1.1e-93 308.7 47.1 7.4e-07 29.3 0.0 37.0 28 17 2 30 30 29 18 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS32639.1 - 1.1e-59 198.5 33.7 3.1e-05 23.9 0.1 26.1 26 0 0 26 26 26 15 CD80-like C2-set immunoglobulin domain EGF_CA PF07645.15 CDS32639.1 - 7e-52 173.4 94.9 3.5e-10 39.9 4.0 9.4 8 0 0 8 8 8 7 Calcium-binding EGF domain TSP_1 PF00090.19 CDS32639.1 - 1.1e-51 172.8 92.1 5.5e-13 48.9 7.4 7.4 6 1 0 6 6 6 5 Thrombospondin type 1 domain Ig_6 PF18452.1 CDS32639.1 - 3.9e-38 128.8 2.5 0.62 9.7 0.0 23.7 27 0 0 27 27 25 6 Immunoglobulin domain cEGF PF12662.7 CDS32639.1 - 5.5e-29 99.7 51.4 8.1e-10 38.5 2.5 9.5 8 0 0 8 8 8 6 Complement Clr-like EGF-like Izumo-Ig PF16706.5 CDS32639.1 - 1.6e-28 98.6 7.4 0.44 10.6 0.0 19.9 24 0 0 24 24 21 5 Izumo-like Immunoglobulin domain C1-set PF07654.15 CDS32639.1 - 2.8e-20 72.5 7.8 2 8.9 0.0 18.9 22 0 0 22 22 20 2 Immunoglobulin C1-set domain Adeno_E3_CR1 PF02440.15 CDS32639.1 - 2.3e-13 49.7 12.5 1 9.2 0.0 15.0 18 0 0 18 18 17 2 Adenovirus E3 region protein CR1 FXa_inhibition PF14670.6 CDS32639.1 - 6.4e-11 42.3 108.1 1.2e-06 28.7 8.2 9.2 9 0 0 9 9 7 6 Coagulation Factor Xa inhibitory site Receptor_2B4 PF11465.8 CDS32639.1 - 4e-10 39.8 0.2 5.3 7.3 0.0 11.3 13 1 1 14 14 13 1 Natural killer cell receptor 2B4 C2-set PF05790.15 CDS32639.1 - 4.4e-09 36.4 4.3 17 5.7 0.0 11.5 14 0 0 14 14 12 0 Immunoglobulin C2-set domain G2F PF07474.12 CDS32639.1 - 9e-09 35.4 0.0 4.4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 G2F domain EGF_3 PF12947.7 CDS32639.1 - 1.9e-06 28.0 68.1 0.0033 17.6 5.8 8.1 7 0 0 7 7 7 5 EGF domain EGF PF00008.27 CDS32639.1 - 7.3e-06 26.2 89.5 0.05 13.9 12.5 8.9 7 0 0 7 7 7 5 EGF-like domain hEGF PF12661.7 CDS32639.1 - 0.0034 17.9 69.7 0.015 15.9 5.5 9.7 7 0 0 7 7 7 4 Human growth factor-like EGF ACAS_N PF16177.5 CDS32639.1 - 0.04 13.8 1.4 47 4.0 0.1 5.2 5 0 0 5 5 5 0 Acetyl-coenzyme A synthetase N-terminus AKAP95 PF04988.12 CDS32641.1 - 0.0012 19.1 0.7 0.098 12.9 0.1 2.5 2 1 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-Di19 PF05605.12 CDS32641.1 - 0.0053 17.0 0.2 0.0093 16.2 0.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding PP_M1 PF03012.14 CDS32641.1 - 2.7 7.5 5.6 1.3 8.5 0.5 2.1 2 0 0 2 2 2 0 Phosphoprotein Serpin PF00079.20 CDS32642.2 - 3.6e-13 49.6 0.0 4.6e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Tyr_Deacylase PF02580.16 CDS32643.1 - 0.06 13.9 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Transposase_1 PF01359.18 CDS32644.1 - 8e-06 25.6 0.2 8e-06 25.6 0.2 1.8 2 0 0 2 2 2 1 Transposase (partial DDE domain) DUF423 PF04241.15 CDS32647.1 - 1.4e-20 73.3 0.0 2.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF4383 PF14325.6 CDS32647.1 - 0.027 14.8 1.8 0.032 14.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) RRF PF01765.19 CDS32648.2 - 2.1e-05 24.5 4.3 2.1e-05 24.5 4.3 2.8 2 1 1 3 3 3 2 Ribosome recycling factor DUF885 PF05960.11 CDS32648.2 - 0.017 14.8 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) YlqD PF11068.8 CDS32648.2 - 1.1 9.6 8.7 0.1 13.0 4.1 1.7 2 0 0 2 2 2 0 YlqD protein SNARE PF05739.19 CDS32649.2 - 5.5e-16 58.3 1.1 5.5e-16 58.3 1.1 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CDS32649.2 - 8.1e-07 28.9 6.4 8.1e-07 28.9 6.4 2.1 2 1 0 2 2 2 1 Syntaxin DUF1818 PF08848.11 CDS32649.2 - 0.0054 16.8 6.4 1.1 9.3 0.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1818) DUF5345 PF17280.2 CDS32649.2 - 0.0074 16.2 0.4 0.027 14.4 0.4 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5345) Goodbye PF17109.5 CDS32649.2 - 0.033 14.6 0.7 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain MCPsignal PF00015.21 CDS32649.2 - 0.039 13.8 1.6 0.34 10.7 0.4 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF5527 PF17665.1 CDS32649.2 - 0.047 13.2 1.3 0.051 13.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DUF2157 PF09925.9 CDS32649.2 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) TMPIT PF07851.13 CDS32649.2 - 0.065 12.5 4.6 1.6 7.9 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DDE_Tnp_IS240 PF13610.6 CDS32649.2 - 0.073 13.3 0.4 0.14 12.4 0.1 1.6 2 1 0 2 2 2 0 DDE domain ING PF12998.7 CDS32649.2 - 0.1 13.2 9.7 0.085 13.5 0.6 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 CDS32649.2 - 0.14 12.3 8.0 0.16 12.0 0.1 3.3 4 0 0 4 4 4 0 Swi5 Syntaxin_2 PF14523.6 CDS32649.2 - 0.47 10.9 12.9 0.31 11.4 3.8 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.11 CDS32649.2 - 0.65 10.3 7.1 87 3.5 6.9 3.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 CDS32649.2 - 2 9.1 5.9 12 6.6 2.6 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HMG_box PF00505.19 CDS32650.1 - 2.6e-20 72.6 2.3 5.4e-20 71.6 2.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS32650.1 - 8.8e-10 39.0 1.3 2.3e-09 37.7 1.3 1.7 1 0 0 1 1 1 1 HMG-box domain CTNNB1_binding PF08347.11 CDS32650.1 - 0.0033 17.7 3.0 0.0033 17.7 3.0 4.4 5 0 0 5 5 5 1 N-terminal CTNNB1 binding WD40 PF00400.32 CDS32651.2 - 9.1e-30 102.3 8.4 7.3e-05 23.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32651.2 - 7.7e-08 32.5 0.1 0.43 10.9 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 CDS32653.1 - 2.5e-21 75.3 7.1 4.4e-21 74.5 7.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32653.1 - 0.21 11.5 1.9 0.34 10.8 0.7 2.0 2 0 0 2 2 2 0 Homeobox KN domain Transposase_1 PF01359.18 CDS32654.1 - 5.6e-16 58.1 0.3 2.1e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Transposase (partial DDE domain) HTH_48 PF17906.1 CDS32654.1 - 5.4e-06 26.4 0.1 1.9e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 HTH domain in Mos1 transposase Sec16_C PF12931.7 CDS32655.1 - 3e-32 112.5 0.0 6.4e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CDS32655.1 - 0.22 12.1 1.1 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region zf-HIT PF04438.16 CDS32656.1 - 6.7e-07 29.1 14.5 6.7e-07 29.1 14.5 1.7 2 0 0 2 2 2 1 HIT zinc finger Parvo_NS1 PF01057.17 CDS32658.2 - 1.7e-21 76.5 0.0 2.5e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS32658.2 - 1.1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase Lon_2 PF13337.6 CDS32658.2 - 0.00033 19.4 0.0 0.005 15.5 0.0 2.1 1 1 1 2 2 2 1 Putative ATP-dependent Lon protease AAA_22 PF13401.6 CDS32658.2 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CDS32658.2 - 0.027 14.2 0.0 3.8 7.2 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CDS32658.2 - 0.027 14.8 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase VirE PF05272.11 CDS32658.2 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E TniB PF05621.11 CDS32658.2 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 CDS32658.2 - 0.18 11.7 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDS32658.2 - 0.19 12.2 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 CDS32661.1 - 2e-13 50.1 0.0 1.3e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS32661.1 - 1.9e-06 27.0 0.0 2.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase DUF5554 PF17709.1 CDS32661.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5554) MT-A70 PF05063.14 CDS32663.1 - 5e-50 169.8 0.1 1e-49 168.7 0.1 1.5 1 1 0 1 1 1 1 MT-A70 IRS PF02174.17 CDS32664.1 - 9.3e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Pkinase_Tyr PF07714.17 CDS32666.1 - 1.4e-91 306.4 0.0 1.8e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS32666.1 - 5.6e-44 150.5 0.0 8e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS32666.1 - 7.8e-19 67.6 0.0 1.8e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDS32666.1 - 1.1e-15 56.9 0.0 2.8e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS32666.1 - 3.1e-11 42.9 0.0 8.3e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS32666.1 - 1.1e-10 41.0 0.0 3.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.6 CDS32666.1 - 0.00054 19.4 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SH3_10 PF17902.1 CDS32666.1 - 0.00083 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Haspin_kinase PF12330.8 CDS32666.1 - 0.0021 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SH3_3 PF08239.11 CDS32666.1 - 0.0038 17.5 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain RIO1 PF01163.22 CDS32666.1 - 0.0043 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family SH2_2 PF14633.6 CDS32666.1 - 0.0049 16.3 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 CDS32666.1 - 0.07 13.0 0.3 0.53 10.2 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sedlin_N PF04628.13 CDS32667.1 - 1.3e-05 25.3 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RGS PF00615.19 CDS32668.1 - 8.2e-33 113.2 0.2 1.4e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ras PF00071.22 CDS32670.1 - 1.5e-23 83.2 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS32670.1 - 2.1e-05 24.7 0.0 6.7e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS32670.1 - 0.00028 20.4 0.1 0.001 18.5 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.19 CDS32670.1 - 0.043 13.4 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HTH_1 PF00126.27 CDS32671.1 - 0.069 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family tRNA-synt_2d PF01409.20 CDS32672.2 - 9.9e-47 159.5 0.1 8.6e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CDS32672.2 - 3.5e-18 65.8 0.0 9.9e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain ThrE PF06738.12 CDS32674.1 - 0.25 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter BAF250_C PF12031.8 CDS32675.1 - 6.9e-89 297.5 1.5 1.1e-88 296.8 1.5 1.3 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ARID PF01388.21 CDS32675.1 - 7.3e-15 55.4 0.3 1.7e-14 54.3 0.3 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Lectin_C PF00059.21 CDS32676.1 - 4.3e-29 101.4 8.2 1.2e-07 32.4 0.2 7.3 6 1 0 6 6 6 5 Lectin C-type domain Kringle PF00051.18 CDS32676.1 - 1.7e-05 25.1 1.0 0.0014 18.9 0.5 3.2 2 0 0 2 2 2 1 Kringle domain UL45 PF05473.12 CDS32676.1 - 0.15 11.7 2.5 23 4.5 0.0 4.2 4 0 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Pkinase PF00069.25 CDS32677.2 - 1.5e-29 103.2 0.0 2.6e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32677.2 - 1.7e-12 47.2 0.0 3.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DMAP1 PF05499.12 CDS32678.1 - 7.6e-39 133.2 0.8 3.2e-38 131.2 0.8 1.9 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CDS32678.1 - 8.2e-26 90.0 0.5 1.5e-25 89.2 0.5 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 NINJA_B PF16136.5 CDS32678.1 - 0.051 14.0 4.8 0.18 12.2 4.8 1.9 1 0 0 1 1 1 0 Putative nuclear localisation signal Neur_chan_LBD PF02931.23 CDS32679.1 - 3.1e-45 154.3 0.1 5e-45 153.6 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CDS32679.1 - 1e-20 74.8 10.5 3.5e-20 73.1 10.5 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Cad PF03596.13 CDS32679.1 - 0.052 13.4 0.3 0.052 13.4 0.3 1.7 3 0 0 3 3 3 0 Cadmium resistance transporter L_HMGIC_fpl PF10242.9 CDS32681.1 - 4.3e-24 85.7 13.5 8.6e-24 84.7 13.5 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CDS32681.1 - 1.9e-06 27.7 7.8 1.9e-06 27.7 7.8 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction G-alpha PF00503.20 CDS32682.1 - 9e-125 416.5 3.9 1.2e-124 416.1 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDS32682.1 - 2.4e-17 63.0 3.1 3.9e-13 49.2 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS32682.1 - 1.8e-05 24.2 5.1 0.0011 18.4 2.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDS32682.1 - 4.4e-05 23.7 1.0 0.1 12.8 0.2 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS32682.1 - 0.0036 16.9 2.5 0.13 11.8 0.8 2.3 2 0 0 2 2 2 2 Ras family TniB PF05621.11 CDS32682.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 CDS32682.1 - 0.059 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-HC5HC2H PF13771.6 CDS32684.1 - 6.8e-11 42.3 6.7 6.8e-11 42.3 6.7 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDS32684.1 - 2.3e-08 34.2 6.2 5.8e-08 32.9 6.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C4pol PF14260.6 CDS32684.1 - 0.076 13.5 0.5 0.076 13.5 0.5 1.9 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.11 CDS32684.1 - 0.11 12.9 3.7 0.32 11.4 3.7 1.8 1 0 0 1 1 1 0 RING-like domain Ribosomal_L2_C PF03947.18 CDS32687.1 - 2.8e-45 153.6 4.6 7e-45 152.3 4.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDS32687.1 - 1.2e-17 63.6 0.1 3.3e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4503 PF14951.6 CDS32687.1 - 1.2e-11 43.7 1.1 2.3e-11 42.8 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) Kelch_1 PF01344.25 CDS32688.1 - 3.2e-75 247.5 14.2 5.2e-17 61.2 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CDS32688.1 - 3.2e-49 163.7 7.4 4.7e-08 33.0 0.1 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDS32688.1 - 5.8e-35 118.0 1.7 1.6e-09 37.4 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CDS32688.1 - 1e-31 108.6 9.5 1.4e-06 28.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS32688.1 - 1.4e-27 95.4 2.9 2.2e-05 24.4 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 CDS32688.1 - 1.4e-25 89.6 0.5 2.3e-25 89.0 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDS32688.1 - 2.4e-25 88.6 0.2 2.4e-25 88.6 0.2 2.5 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDS32688.1 - 1.3e-12 47.4 7.4 0.0012 18.8 0.0 6.1 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.6 CDS32688.1 - 0.68 10.5 5.2 15 6.2 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain Exo_endo_phos PF03372.23 CDS32689.1 - 2.3e-18 66.6 0.0 3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CDS32689.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AMP-binding PF00501.28 CDS32690.1 - 4.2e-91 305.7 0.0 5.9e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDS32690.1 - 4.1e-05 24.5 0.0 0.00017 22.5 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ice_nucleation PF00818.17 CDS32690.1 - 0.066 13.3 3.5 0.2 11.8 3.5 1.8 1 0 0 1 1 1 0 Ice nucleation protein repeat PhoLip_ATPase_C PF16212.5 CDS32692.2 - 1.8e-54 185.1 30.9 1.8e-54 185.1 30.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CDS32692.2 - 1.2e-13 51.9 0.0 8.8e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDS32692.2 - 3.2e-11 43.1 1.1 1.7e-10 40.7 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDS32692.2 - 6.8e-07 29.3 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) HAD PF12710.7 CDS32692.2 - 0.014 15.8 0.0 6.2 7.2 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDS32692.2 - 0.07 12.9 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 CDS32693.1 - 2.3e-56 191.3 26.6 2.3e-56 191.3 26.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDS32693.1 - 7.2e-17 60.8 2.1 7.2e-17 60.8 2.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CDS32693.1 - 1.4e-09 37.8 0.2 1.1e-08 34.8 0.2 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDS32693.1 - 2.3e-09 37.9 0.0 5.7e-05 23.5 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDS32693.1 - 3.1e-09 36.8 0.0 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDS32693.1 - 0.067 12.9 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1622 PF07784.11 CDS32693.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) adh_short PF00106.25 CDS32694.1 - 9.5e-18 64.3 3.1 9.5e-09 35.0 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 CDS32694.1 - 1.3e-10 41.2 1.0 3.2e-07 30.2 0.1 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ACR_tran PF00873.19 CDS32694.1 - 0.067 10.8 0.2 0.091 10.4 0.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Trp_leader2 PF08056.11 CDS32694.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Tryptophan operon leader peptide GCD14 PF08704.10 CDS32695.1 - 6e-68 229.2 0.0 1.1e-67 228.3 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDS32695.1 - 8.1e-12 45.2 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDS32695.1 - 6.3e-09 35.9 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDS32695.1 - 5.2e-07 30.3 0.1 1.2e-06 29.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain GCD14_N PF14801.6 CDS32695.1 - 2.6e-05 23.9 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 CDS32695.1 - 0.00012 21.5 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDS32695.1 - 0.00055 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDS32695.1 - 0.00057 19.3 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CDS32695.1 - 0.0026 18.4 0.0 0.005 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CDS32695.1 - 0.0044 18.0 0.0 0.0085 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CDS32695.1 - 0.005 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 CDS32695.1 - 0.0099 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS32695.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.17 CDS32695.1 - 0.042 13.0 0.0 0.095 11.9 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_2 PF00891.18 CDS32695.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 CDS32695.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 CDS32695.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 CDS32695.1 - 0.16 11.5 0.0 0.55 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Claudin_2 PF13903.6 CDS32696.1 - 0.00065 19.5 0.7 0.0012 18.6 0.7 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Alg6_Alg8 PF03155.15 CDS32698.1 - 0.16 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family DUF1849 PF08904.11 CDS32699.1 - 0.0053 16.3 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1849) Homeodomain PF00046.29 CDS32700.1 - 1.2e-06 28.2 0.4 2.3e-06 27.3 0.4 1.5 1 0 0 1 1 1 1 Homeodomain DUF357 PF04010.13 CDS32701.1 - 0.033 14.3 0.3 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) ASC PF00858.24 CDS32702.1 - 1.3e-68 232.0 5.8 2.2e-68 231.2 5.8 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel V-set PF07686.17 CDS32703.1 - 1.7e-11 44.2 0.0 4.2e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.6 CDS32703.1 - 8.2e-08 32.7 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS32703.1 - 7.2e-07 29.3 0.0 1.6e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS32703.1 - 7.4e-07 29.1 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS32703.1 - 8.4e-05 22.8 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_6 PF18452.1 CDS32703.1 - 0.0016 18.0 0.0 0.0056 16.2 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.16 CDS32703.1 - 0.006 15.4 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.11 CDS32703.1 - 0.023 14.7 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain C1-set PF07654.15 CDS32703.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Ceramidse_alk_C PF17048.5 CDS32704.1 - 0.0013 18.6 0.2 0.0014 18.5 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MRP-S31 PF15433.6 CDS32705.1 - 3.2e-47 161.7 5.0 4.1e-47 161.4 5.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Kelch_1 PF01344.25 CDS32706.1 - 2.9e-56 186.8 14.8 2.8e-12 46.0 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CDS32706.1 - 4e-36 122.1 5.8 1.2e-08 34.9 0.0 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CDS32706.1 - 1.6e-22 78.6 1.2 6e-05 22.9 0.0 6.2 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 CDS32706.1 - 5e-21 74.7 1.1 5e-21 74.7 1.1 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CDS32706.1 - 1.4e-17 63.4 8.6 0.0013 18.7 0.0 5.7 5 1 1 6 6 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS32706.1 - 5.6e-17 61.6 8.2 0.036 14.4 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain S4 PF01479.25 CDS32706.1 - 1.8e-09 37.2 0.6 4.7e-09 35.8 0.6 1.8 1 0 0 1 1 1 1 S4 domain Kelch_5 PF13854.6 CDS32706.1 - 9.6e-09 35.0 8.4 0.65 10.0 0.1 5.6 5 0 0 5 5 5 3 Kelch motif BTB PF00651.31 CDS32706.1 - 1.4e-06 28.5 0.0 3.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S4 PF00163.19 CDS32706.1 - 1.5e-05 25.8 0.1 1.5e-05 25.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain DUF3342 PF11822.8 CDS32706.1 - 0.059 13.6 0.0 0.42 10.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) HMG_box PF00505.19 CDS32707.1 - 2.4e-11 43.9 2.4 6.5e-07 29.7 1.3 3.2 1 1 1 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS32707.1 - 1.1e-08 35.6 1.3 1.6e-07 31.8 0.6 2.7 1 1 1 2 2 2 1 HMG-box domain Ras PF00071.22 CDS32708.1 - 1.7e-61 206.6 0.1 2e-61 206.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS32708.1 - 8.7e-33 113.1 0.0 2.2e-32 111.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS32708.1 - 7e-12 45.2 0.0 7.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDS32708.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS32708.1 - 0.00089 19.2 0.1 0.27 11.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CDS32708.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDS32708.1 - 0.0044 16.6 0.1 0.025 14.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CDS32708.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 CDS32708.1 - 0.097 12.9 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain TRAP_alpha PF03896.16 CDS32709.1 - 1.1e-37 129.8 0.0 1.4e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit ABC_membrane PF00664.23 CDS32709.1 - 0.019 14.6 0.6 0.064 12.9 0.2 1.9 1 1 1 2 2 2 0 ABC transporter transmembrane region DUF4834 PF16118.5 CDS32709.1 - 0.023 15.6 0.1 0.038 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1616 PF07760.11 CDS32709.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF4577 PF15145.6 CDS32709.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) RIBIOP_C PF04950.12 CDS32710.1 - 2.7e-91 306.1 1.3 2.7e-91 306.0 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDS32710.1 - 0.0025 17.9 0.0 0.016 15.3 0.0 2.3 1 1 0 1 1 1 1 AARP2CN (NUC121) domain 7TM_GPCR_Srw PF10324.9 CDS32712.1 - 2e-22 79.9 19.8 6.2e-16 58.6 12.2 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS32712.1 - 5.4e-15 55.4 8.9 5.4e-15 55.4 8.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CTV_P6 PF06706.11 CDS32712.1 - 0.88 9.3 5.3 0.19 11.5 1.0 2.1 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF2644 PF10841.8 CDS32713.1 - 0.021 15.1 1.0 0.021 15.1 1.0 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2644) Shisa PF13908.6 CDS32713.1 - 1.9 8.7 8.7 11 6.2 0.0 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Renin_r PF07850.14 CDS32713.1 - 2.8 8.6 8.3 0.25 12.0 0.3 2.5 1 1 2 3 3 3 0 Renin receptor-like protein Ank_2 PF12796.7 CDS32714.1 - 6.8e-30 103.5 0.5 2.4e-14 53.7 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32714.1 - 2.1e-27 95.1 2.3 2e-06 28.2 0.1 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32714.1 - 3.3e-18 63.9 5.6 0.0005 20.3 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 CDS32714.1 - 1.1e-17 63.9 5.9 2.3e-07 30.9 0.0 5.0 3 3 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS32714.1 - 3.8e-14 52.4 7.5 0.0061 17.0 0.1 5.5 4 2 1 5 5 5 4 Ankyrin repeat FAINT PF04385.15 CDS32714.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, DUF529 zf-MYND PF01753.18 CDS32716.1 - 0.0059 16.7 15.2 0.0059 16.7 15.2 3.8 3 1 0 3 3 3 1 MYND finger Phage_GP20 PF06810.11 CDS32716.1 - 0.028 14.2 1.0 0.072 12.9 1.0 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.15 CDS32716.1 - 0.073 12.8 1.0 0.34 10.7 1.4 1.8 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.19 CDS32716.1 - 0.11 12.2 3.0 0.23 11.1 3.0 1.5 1 0 0 1 1 1 0 GrpE TolA_bind_tri PF16331.5 CDS32716.1 - 0.14 12.3 4.1 0.3 11.2 4.1 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 CDS32716.1 - 0.18 12.0 4.6 0.54 10.5 4.6 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 CDS32716.1 - 7.7 6.6 16.2 0.082 12.9 1.5 3.0 2 0 0 2 2 2 0 FlxA-like protein Homeodomain PF00046.29 CDS32718.1 - 3e-30 103.9 16.4 1.8e-15 56.5 2.9 3.9 3 0 0 3 3 3 2 Homeodomain zf-H2C2_5 PF13909.6 CDS32718.1 - 0.00018 21.2 8.0 0.0022 17.7 0.0 3.1 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 CDS32718.1 - 0.00088 19.6 22.7 0.028 14.8 0.2 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type Homeobox_KN PF05920.11 CDS32718.1 - 0.002 18.0 2.7 0.65 9.9 0.2 3.0 2 0 0 2 2 2 2 Homeobox KN domain HOCHOB PF17943.1 CDS32718.1 - 0.0054 17.4 2.4 3.6 8.3 0.3 3.8 4 0 0 4 4 4 2 Homeobox-cysteine loop-homeobox Vps36-NZF-N PF16988.5 CDS32718.1 - 0.015 14.7 0.2 5.2 6.5 0.0 4.1 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2 PF00096.26 CDS32718.1 - 0.054 14.0 0.2 0.054 14.0 0.2 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF816 PF05674.12 CDS32720.1 - 0.71 9.8 3.3 5.1 7.0 0.1 3.1 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF816) Bromo_TP_like PF17027.5 CDS32721.1 - 0.1 12.7 1.0 20 5.4 0.4 2.4 2 0 0 2 2 2 0 Histone-fold protein Ribosomal_L19 PF01245.20 CDS32722.1 - 2.4e-10 40.3 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 MFS_1 PF07690.16 CDS32723.1 - 5.2e-30 104.6 29.5 1.6e-23 83.2 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF423 PF04241.15 CDS32723.1 - 1.6 9.0 7.3 7.5 6.8 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF423) SH3_10 PF17902.1 CDS32724.1 - 0.00047 20.2 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 SH3 domain DnaJ_CXXCXGXG PF00684.19 CDS32724.1 - 0.51 10.7 12.9 9.7 6.6 0.0 4.6 5 0 0 5 5 5 0 DnaJ central domain THOC7 PF05615.13 CDS32724.1 - 1.7 8.9 5.5 2.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Tho complex subunit 7 Kinesin PF00225.23 CDS32725.1 - 1.1e-189 629.4 0.0 6e-94 314.7 0.0 2.7 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CDS32725.1 - 2e-40 138.2 0.0 4.2e-20 72.2 0.0 3.1 2 0 0 2 2 2 2 Microtubule binding WD40 PF00400.32 CDS32725.1 - 2e-13 50.6 9.9 0.02 15.8 0.0 7.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Kinesin_assoc PF16183.5 CDS32725.1 - 3.4e-07 30.6 4.6 0.0067 16.6 0.1 4.4 3 0 0 3 3 3 2 Kinesin-associated ANAPC4_WD40 PF12894.7 CDS32725.1 - 2.9e-06 27.5 0.0 0.37 11.1 0.0 4.6 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4527 PF15030.6 CDS32725.1 - 0.0044 16.5 9.1 0.042 13.3 5.2 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4527) DASH_Dad4 PF08650.10 CDS32725.1 - 0.68 9.9 3.0 18 5.4 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 FAR1 PF03101.15 CDS32726.1 - 9.3e-07 29.5 0.1 2.1e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain Mig-14 PF07395.11 CDS32726.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.6 1 1 0 1 1 1 0 Mig-14 zf-CCCH PF00642.24 CDS32728.1 - 5.9e-07 29.3 11.1 0.0041 17.0 0.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS32728.1 - 2.8e-05 24.0 9.9 0.0031 17.5 0.7 3.1 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CDS32728.1 - 0.0022 18.2 2.7 0.0063 16.7 2.7 1.8 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 CDS32728.1 - 0.0029 18.3 12.0 0.16 12.7 1.7 3.1 2 1 1 3 3 3 2 Torus domain zf-C3H1 PF10650.9 CDS32728.1 - 0.014 15.1 6.7 0.11 12.2 2.4 2.8 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDS32728.1 - 0.073 13.6 12.6 0.29 11.7 2.5 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger IMUP PF15761.5 CDS32728.1 - 3.5 8.4 12.5 0.076 13.7 4.4 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDS32728.1 - 6.3 6.3 16.1 4.3 6.9 6.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MMS1_N PF10433.9 CDS32729.2 - 3.9e-61 207.2 0.0 1e-53 182.7 0.0 3.0 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDS32729.2 - 3.3e-46 158.1 0.0 8.3e-46 156.8 0.0 1.7 1 1 0 1 1 1 1 CPSF A subunit region PQQ_3 PF13570.6 CDS32729.2 - 0.24 11.9 3.3 15 6.2 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain Hormone_recep PF00104.30 CDS32730.1 - 3e-13 49.8 1.5 5.7e-13 48.9 1.5 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF1780 PF08682.10 CDS32731.2 - 0.0038 16.9 0.5 0.0071 16.0 0.5 1.4 1 0 0 1 1 1 1 Putative endonuclease, protein of unknown function (DUF1780) DUF3072 PF11272.8 CDS32731.2 - 0.02 14.8 0.4 0.041 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Metallophos PF00149.28 CDS32732.1 - 3.1e-38 132.3 0.1 4e-38 132.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDS32732.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MFS_1 PF07690.16 CDS32733.1 - 4.5e-18 65.3 20.4 4.5e-18 65.3 20.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TraS PF10624.9 CDS32733.1 - 0.95 9.4 5.7 0.45 10.4 1.6 2.6 3 0 0 3 3 3 0 Plasmid conjugative transfer entry exclusion protein TraS zf-C2H2_4 PF13894.6 CDS32734.1 - 2.5e-15 55.8 58.5 0.002 18.8 0.4 9.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS32734.1 - 3.3e-15 55.6 66.4 0.001 19.4 0.4 8.9 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS32734.1 - 1.1e-12 47.7 52.5 0.00054 20.3 2.7 8.8 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS32734.1 - 3.4e-07 30.4 20.8 0.011 16.0 0.2 6.8 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CDS32734.1 - 0.00028 20.6 4.2 0.00028 20.6 4.2 6.3 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-met PF12874.7 CDS32734.1 - 0.00044 20.6 4.8 0.0059 17.0 0.4 7.5 8 0 0 8 8 7 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CDS32734.1 - 0.0023 18.2 26.1 0.012 15.9 4.7 3.7 3 1 0 3 3 2 2 C2H2-type zinc ribbon Actin_micro PF17003.5 CDS32734.1 - 0.0037 16.5 2.3 91 2.1 6.4 3.6 1 1 2 3 3 3 0 Putative actin-like family zf-C2H2_6 PF13912.6 CDS32734.1 - 0.037 14.0 0.4 0.037 14.0 0.4 6.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS32734.1 - 0.12 12.1 13.9 1.1 9.1 0.1 5.1 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDS32734.1 - 4.5 7.5 9.8 18 5.5 0.3 3.7 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.14 CDS32734.1 - 6.5 6.8 9.5 1.6 8.8 1.6 3.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid Actin PF00022.19 CDS32735.1 - 5.7e-09 35.1 0.0 5.7e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.19 CDS32738.1 - 1.3e-43 149.1 0.0 3.9e-23 81.7 0.0 3.0 1 1 2 3 3 3 3 Actin CH PF00307.31 CDS32739.1 - 2.4e-72 240.1 0.2 7e-19 68.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS32739.1 - 1.6e-09 37.4 0.0 4.2e-05 23.3 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 CDS32739.1 - 0.0032 17.6 0.0 4.6 7.4 0.0 3.6 4 0 0 4 4 4 2 CH-like domain in sperm protein TOH_N PF12549.8 CDS32739.1 - 0.78 9.7 4.7 0.82 9.6 0.2 3.1 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal Cadherin PF00028.17 CDS32740.2 - 4e-43 145.8 7.3 7.1e-16 58.4 0.2 9.0 8 2 0 8 8 8 5 Cadherin domain Cadherin_2 PF08266.12 CDS32740.2 - 3.1e-07 30.2 0.0 0.027 14.3 0.0 4.0 3 0 0 3 3 3 3 Cadherin-like Cadherin_3 PF16184.5 CDS32740.2 - 0.00025 21.0 5.0 2.8 8.0 0.0 5.2 5 0 0 5 5 5 2 Cadherin-like Band_7 PF01145.25 CDS32742.1 - 1.6e-31 109.7 0.7 2.4e-31 109.1 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CDS32742.1 - 0.002 17.9 0.1 0.0031 17.3 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family GP68 PF17469.2 CDS32742.1 - 0.074 13.5 0.4 0.17 12.3 0.4 1.6 1 0 0 1 1 1 0 Phage protein Gp68 ORC2 PF04084.14 CDS32743.1 - 9.6e-86 287.7 0.0 1.3e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 P22_Tail-4 PF11650.8 CDS32743.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor GCM PF03615.15 CDS32745.1 - 1e-35 122.7 0.2 2.1e-35 121.7 0.2 1.5 1 0 0 1 1 1 1 GCM motif protein Seipin PF06775.14 CDS32745.1 - 5e-14 52.9 0.1 1.1e-13 51.7 0.1 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) LRR_4 PF12799.7 CDS32747.1 - 0.00016 22.0 17.5 0.07 13.6 1.3 5.7 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) Lipoprotein_20 PF13942.6 CDS32747.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 YfhG lipoprotein Myosin_tail_1 PF01576.19 CDS32748.2 - 8.6e-70 235.8 154.0 1.2e-69 235.4 154.0 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 CDS32748.2 - 3.4e-16 59.7 137.0 5.8e-06 26.1 8.4 7.6 1 1 4 6 6 6 5 Intermediate filament protein Spc7 PF08317.11 CDS32748.2 - 4.4e-05 22.5 46.2 0.00038 19.4 21.4 7.3 1 1 5 7 7 7 4 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 CDS32748.2 - 0.0017 18.3 5.6 0.0017 18.3 5.6 7.9 7 4 2 9 9 8 1 PDZ domain of MCC-2 bdg protein for Usher syndrome EzrA PF06160.12 CDS32748.2 - 0.0023 16.2 10.4 0.0023 16.2 10.4 5.9 1 1 5 6 6 4 1 Septation ring formation regulator, EzrA HMMR_N PF15905.5 CDS32748.2 - 0.0027 17.3 135.1 0.017 14.6 39.5 6.1 1 1 6 7 7 7 3 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 CDS32748.2 - 0.0029 17.6 7.7 0.0029 17.6 7.7 13.8 6 4 6 13 13 12 2 TolA binding protein trimerisation Tropomyosin_1 PF12718.7 CDS32748.2 - 0.0038 17.4 23.1 0.0038 17.4 23.1 9.0 1 1 4 8 8 7 2 Tropomyosin like DUF1664 PF07889.12 CDS32748.2 - 0.0043 17.1 86.0 0.83 9.7 0.9 10.9 2 2 10 13 13 13 7 Protein of unknown function (DUF1664) Lebercilin PF15619.6 CDS32748.2 - 0.0047 16.6 32.8 0.0047 16.6 32.8 7.9 2 2 6 8 8 8 3 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 CDS32748.2 - 0.0051 16.9 10.5 0.0051 16.9 10.5 10.7 2 2 8 11 11 10 4 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 CDS32748.2 - 0.0085 15.8 23.0 0.0085 15.8 23.0 7.7 1 1 7 8 8 7 2 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 CDS32748.2 - 0.03 14.8 132.9 1.9 8.9 25.2 7.4 1 1 5 6 6 6 0 Fez1 SNCAIP_SNCA_bd PF16700.5 CDS32748.2 - 0.032 14.0 0.7 0.2 11.4 0.0 2.8 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain ATG16 PF08614.11 CDS32748.2 - 0.051 13.8 164.0 0.34 11.1 9.3 8.9 1 1 5 7 7 7 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 CDS32748.2 - 0.076 12.8 142.0 0.016 15.1 22.2 8.0 1 1 5 6 6 6 0 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 CDS32748.2 - 0.16 10.5 113.5 0.12 11.0 28.8 5.9 1 1 5 6 6 6 0 AAA domain Wyosine_form PF08608.12 CDS32748.2 - 0.17 12.2 0.2 0.87 10.0 0.2 2.2 1 0 0 1 1 1 0 Wyosine base formation Jnk-SapK_ap_N PF09744.9 CDS32748.2 - 0.31 11.3 147.6 0.3 11.3 14.9 9.1 2 2 7 9 9 9 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 CDS32748.2 - 0.39 8.2 133.2 0.011 13.3 50.3 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 CDS32748.2 - 0.44 10.6 73.1 0.49 10.4 3.2 8.8 1 1 8 9 9 9 0 Baculovirus polyhedron envelope protein, PEP, C terminus HOOK PF05622.12 CDS32748.2 - 6.5 4.8 137.4 0.0045 15.2 17.7 5.5 1 1 5 6 6 5 0 HOOK protein CortBP2 PF09727.9 CDS32750.2 - 4.4e-32 111.5 15.2 6.2e-32 111.1 15.2 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Spc7 PF08317.11 CDS32750.2 - 0.009 14.9 12.8 0.013 14.4 12.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FapA PF03961.13 CDS32750.2 - 0.49 9.0 4.8 0.74 8.3 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 CDS32750.2 - 0.69 10.4 21.7 0.15 12.6 13.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region betaPIX_CC PF16523.5 CDS32750.2 - 0.88 9.4 5.3 0.41 10.5 2.0 2.0 2 0 0 2 2 2 0 betaPIX coiled coil UPF0242 PF06785.11 CDS32750.2 - 1.3 9.1 12.8 2.2 8.3 12.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CDS32750.2 - 4.8 6.4 10.2 7.4 5.8 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2968 PF11180.8 CDS32750.2 - 6.3 6.4 16.4 48 3.5 16.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF641 PF04859.12 CDS32750.2 - 6.9 7.0 14.6 14 6.0 2.8 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 CDS32750.2 - 7 6.1 9.4 11 5.5 9.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit tRNA-synt_2 PF00152.20 CDS32751.1 - 8.6e-92 307.6 0.0 1e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RRM_1 PF00076.22 CDS32752.1 - 1.3e-35 121.0 0.1 2.6e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS32752.1 - 1.5e-08 34.6 0.2 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS32752.1 - 0.011 15.7 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS32752.1 - 0.03 14.3 0.2 2.6 8.1 0.0 2.5 2 1 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 CDS32752.1 - 0.1 12.3 0.1 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_1 PF00076.22 CDS32754.1 - 6.7e-24 83.5 0.1 1.8e-18 66.1 0.1 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS32754.1 - 1.4e-06 28.4 0.0 0.00045 20.3 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CDS32754.1 - 3.4e-06 26.9 0.3 0.029 14.2 0.0 3.1 2 1 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 CDS32754.1 - 0.11 12.6 2.3 15 5.7 0.1 3.1 3 1 0 3 3 3 0 RNA binding motif Mpv17_PMP22 PF04117.12 CDS32755.1 - 1.1e-11 44.8 0.3 2.9e-11 43.4 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Proteasome PF00227.26 CDS32756.1 - 5.6e-50 169.5 0.0 7.2e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDS32756.1 - 6.5e-12 44.9 0.2 1.4e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb2_6 PF00562.28 CDS32757.1 - 1.7e-99 333.6 0.0 1.8e-98 330.2 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDS32757.1 - 8.6e-30 103.8 0.0 1.3e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CDS32757.1 - 1.3e-24 86.1 0.0 3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CDS32757.1 - 1.5e-22 79.8 1.0 3.2e-12 46.7 0.2 2.9 2 1 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CDS32757.1 - 1.4e-15 57.0 0.0 3.1e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CDS32757.1 - 4e-07 29.9 0.0 6.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Pesticin PF16754.5 CDS32757.1 - 0.036 14.0 0.0 9.8 6.1 0.0 2.4 1 1 1 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term PHD PF00628.29 CDS32757.1 - 0.27 11.2 2.7 0.76 9.7 2.7 1.8 1 0 0 1 1 1 0 PHD-finger HD PF01966.22 CDS32758.1 - 6.5e-11 42.5 0.0 1.6e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 HD domain PDEase_I PF00233.19 CDS32758.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Tubulin PF00091.25 CDS32759.1 - 1.8e-40 139.2 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Gal-bind_lectin PF00337.22 CDS32760.1 - 4.6e-07 29.4 0.0 4.4e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Galactoside-binding lectin zf-B_box PF00643.24 CDS32761.1 - 1.1e-09 38.3 3.5 1.1e-09 38.3 3.5 5.9 7 1 0 7 7 7 2 B-box zinc finger PHD PF00628.29 CDS32761.1 - 1.1e-08 34.8 5.5 1.1e-08 34.8 5.5 5.6 4 2 0 4 4 4 1 PHD-finger Talin_middle PF09141.10 CDS32761.1 - 0.088 12.8 1.3 0.25 11.4 0.4 2.0 1 1 1 2 2 2 0 Talin, middle domain TPR_MLP1_2 PF07926.12 CDS32761.1 - 0.12 12.5 1.1 0.23 11.5 0.3 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TPR_7 PF13176.6 CDS32762.2 - 0.014 15.4 0.2 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32762.2 - 0.028 14.7 1.6 1.6 9.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS32762.2 - 0.21 11.8 0.7 40 4.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2806 PF10987.8 CDS32765.2 - 0.055 13.3 0.1 0.071 13.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2806) Rad51 PF08423.11 CDS32767.2 - 1.1e-19 70.7 0.0 1.3e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Rad51 Rad51 PF08423.11 CDS32770.1 - 3.5e-09 36.3 0.2 4.8e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 Rad51 zf-H2C2_2 PF13465.6 CDS32774.2 - 0.036 14.5 0.3 0.086 13.3 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zf-met PF12874.7 CDS32774.2 - 2.1 8.9 4.8 0.82 10.1 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CDS32775.1 - 4.4e-05 23.7 5.8 0.0046 17.3 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS32775.1 - 0.036 14.5 1.5 0.036 14.5 1.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Alk_phosphatase PF00245.20 CDS32776.1 - 0.02 13.8 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Glyco_hydro_65C PF03633.15 CDS32776.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain CUB PF00431.20 CDS32779.1 - 8.3e-20 71.2 0.0 2e-05 24.9 0.0 5.6 2 1 2 4 4 4 3 CUB domain Pkinase PF00069.25 CDS32780.1 - 2.1e-74 250.2 0.0 3.3e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32780.1 - 3e-39 134.8 0.0 4.7e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32780.1 - 1.6e-06 27.7 0.1 6e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CDS32780.1 - 4.4e-05 22.9 0.1 9.3e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_3 PF13358.6 CDS32781.1 - 0.052 13.3 0.0 0.064 13.0 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease R3H-assoc PF13902.6 CDS32782.1 - 1e-08 35.7 9.2 1.2e-07 32.2 8.7 2.3 1 1 1 2 2 2 1 R3H-associated N-terminal domain Bax1-I PF01027.20 CDS32783.1 - 6.8e-37 127.3 26.9 7.8e-37 127.1 26.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Polysacc_synt_C PF14667.6 CDS32783.1 - 2.4 8.2 25.0 1.5 8.9 14.4 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Glyco_transf_7C PF02709.14 CDS32784.1 - 4.2e-19 68.0 1.0 1.3e-18 66.4 0.7 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDS32784.1 - 1.4e-18 66.8 0.1 2.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 TPR_2 PF07719.17 CDS32785.1 - 2.9e-20 70.7 15.1 0.0036 17.3 0.3 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32785.1 - 7.9e-20 69.8 15.2 1.5e-05 24.6 0.3 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32785.1 - 2.6e-18 66.1 18.2 1.5e-10 41.2 1.4 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS32785.1 - 1.9e-15 55.7 4.6 0.032 14.5 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32785.1 - 3.8e-15 55.3 14.0 0.0023 18.6 0.5 8.3 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32785.1 - 4.1e-12 46.4 12.4 6.9e-05 23.3 1.7 5.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDS32785.1 - 6.9e-12 44.9 13.3 1.6e-06 27.7 0.1 6.7 7 2 1 8 8 8 3 TPR repeat TPR_7 PF13176.6 CDS32785.1 - 1.2e-10 40.7 14.7 0.0022 17.9 0.2 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32785.1 - 1e-09 38.9 17.5 0.22 12.2 3.5 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 CDS32785.1 - 3.2e-09 36.4 15.0 2.1e-05 24.2 1.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDS32785.1 - 4.1e-09 36.4 8.2 1.7e-05 24.9 1.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS32785.1 - 1.4e-08 34.5 11.3 0.17 12.4 0.2 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDS32785.1 - 4.6e-07 29.3 4.4 0.0023 17.2 1.7 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 CDS32785.1 - 5.2e-05 23.5 12.8 0.34 11.7 0.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32785.1 - 0.00052 20.2 12.4 0.02 15.1 0.2 4.3 2 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4919 PF16266.5 CDS32785.1 - 0.002 18.1 0.3 0.086 12.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) TPR_6 PF13174.6 CDS32785.1 - 0.0084 16.7 13.8 6.5 7.6 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS32785.1 - 1.3 9.1 4.0 24 5.1 0.1 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Arm PF00514.23 CDS32786.1 - 5.6e-09 35.7 21.8 0.11 12.6 0.2 7.7 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat SAMP PF05924.11 CDS32786.1 - 2e-07 30.1 1.4 0.0004 19.6 0.4 3.7 3 0 0 3 3 3 2 SAMP Motif APC_r PF05923.12 CDS32786.1 - 9.9e-07 28.3 12.4 0.00048 19.8 0.3 5.0 5 0 0 5 5 5 2 APC repeat APC_rep PF18797.1 CDS32786.1 - 0.036 15.0 0.0 0.11 13.5 0.0 1.9 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat HEAT_2 PF13646.6 CDS32786.1 - 0.72 10.3 4.4 1 9.8 0.5 2.7 2 0 0 2 2 2 0 HEAT repeats SDA1 PF05285.12 CDS32786.1 - 1.7 8.0 4.8 35 3.7 3.7 2.2 2 0 0 2 2 2 0 SDA1 Hormone_3 PF00159.18 CDS32787.1 - 1.9e-05 24.6 0.1 3.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide Docking PF08990.11 CDS32787.1 - 2.2 8.0 6.1 12 5.6 0.5 2.7 2 0 0 2 2 2 0 Erythronolide synthase docking Tetraspanin PF00335.20 CDS32788.1 - 2.1e-33 116.0 26.1 3.3e-33 115.3 26.1 1.3 1 1 0 1 1 1 1 Tetraspanin family YrvL PF14184.6 CDS32788.1 - 0.00024 21.2 7.3 0.00024 21.2 7.3 2.8 3 0 0 3 3 3 1 Regulatory protein YrvL PorA PF11271.8 CDS32788.1 - 0.27 10.5 0.5 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Porin PorA Cyclin_N PF00134.23 CDS32789.1 - 3.1e-34 117.5 0.2 6.4e-34 116.4 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDS32789.1 - 7.9e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase_Tyr PF07714.17 CDS32790.1 - 8.5e-78 261.2 0.0 2.7e-75 253.0 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Recep_L_domain PF01030.24 CDS32790.1 - 2.2e-35 121.2 0.0 5.5e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.25 CDS32790.1 - 9.5e-35 120.2 0.0 2.9e-34 118.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain GF_recep_IV PF14843.6 CDS32790.1 - 4.1e-27 94.6 106.2 1.8e-12 47.2 24.7 5.9 3 2 3 6 6 6 4 Growth factor receptor domain IV Furin-like PF00757.20 CDS32790.1 - 2.8e-26 92.2 111.9 9e-17 61.3 36.5 5.6 3 2 2 5 5 5 4 Furin-like cysteine rich region DUF3875 PF12991.7 CDS32790.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) RRM_1 PF00076.22 CDS32791.1 - 4.1e-19 68.2 0.0 7.9e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VIGSSK PF14773.6 CDS32791.1 - 0.071 13.3 1.8 0.17 12.0 1.8 1.7 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal BAF1_ABF1 PF04684.13 CDS32791.1 - 0.072 12.1 2.7 0.097 11.7 2.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ADH_zinc_N PF00107.26 CDS32792.1 - 6.5e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDS32792.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDS32792.1 - 0.00037 21.5 0.0 0.00072 20.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CDS32793.1 - 6.2e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDS32793.1 - 1.1e-09 38.1 0.0 2.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDS32793.1 - 0.00086 20.4 0.0 0.0016 19.5 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RT_RNaseH_2 PF17919.1 CDS32794.1 - 4.1e-11 42.8 0.1 1.2e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS32794.1 - 3.4e-05 24.1 0.0 9.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CDS32794.1 - 0.0041 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF4271 PF14093.6 CDS32794.1 - 0.019 14.9 8.5 0.034 14.1 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) gag-asp_proteas PF13975.6 CDS32794.1 - 0.022 15.3 0.0 0.094 13.3 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SUR7 PF06687.12 CDS32794.1 - 3.8 7.1 19.1 2.3 7.8 12.9 2.2 1 1 1 2 2 2 0 SUR7/PalI family DUF3995 PF13160.6 CDS32794.1 - 9.3 6.6 8.8 12 6.3 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Integrase_H2C2 PF17921.1 CDS32795.1 - 0.00059 19.9 0.4 0.001 19.1 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Ubiq_cyt_C_chap PF03981.12 CDS32796.1 - 1.1e-33 116.2 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone FYVE PF01363.21 CDS32797.1 - 2.5e-14 53.1 7.5 5.1e-14 52.1 7.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 CDS32797.1 - 2.9e-06 27.9 12.8 2.4e-05 25.0 0.5 5.4 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32797.1 - 0.00019 21.7 0.4 0.5 10.7 0.3 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_9 PF13901.6 CDS32797.1 - 0.0023 17.9 2.1 0.0045 17.0 2.1 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon DUF2688 PF10892.8 CDS32797.1 - 0.032 13.7 2.0 0.073 12.6 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) FYVE_2 PF02318.16 CDS32797.1 - 0.87 9.8 7.1 2.5 8.4 7.1 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 CDS32797.1 - 1.2 9.4 9.0 0.43 10.8 1.6 3.1 3 0 0 3 3 3 0 B-box zinc finger zf-piccolo PF05715.13 CDS32797.1 - 9.2 6.5 10.3 1.5e+02 2.6 10.8 2.5 1 1 1 2 2 2 0 Piccolo Zn-finger EXOSC1 PF10447.9 CDS32798.2 - 9.9e-08 32.6 0.2 2.3e-07 31.4 0.2 1.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 RGS PF00615.19 CDS32798.2 - 0.0055 17.0 0.1 0.023 15.0 0.1 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain ECR1_N PF14382.6 CDS32798.2 - 0.039 13.7 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region ST7 PF04184.12 CDS32799.1 - 1.9e-214 713.1 0.1 2.3e-214 712.9 0.1 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.6 CDS32799.1 - 2e-06 28.0 8.9 3.1e-05 24.3 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS32799.1 - 3.5e-06 27.6 0.7 0.1 13.3 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS32799.1 - 1.5e-05 25.4 9.5 0.091 13.6 0.2 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS32799.1 - 1.6e-05 25.3 4.7 0.00019 21.9 1.8 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 CDS32799.1 - 0.00047 20.0 0.5 0.0011 18.9 0.5 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_2 PF07719.17 CDS32799.1 - 0.004 17.2 0.0 0.004 17.2 0.0 6.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS32799.1 - 0.0093 16.2 4.8 0.042 14.1 1.8 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDS32799.1 - 0.013 15.3 3.9 1.8 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.6 CDS32799.1 - 0.07 12.9 2.4 1.7 8.3 0.0 2.9 1 1 2 3 3 3 0 Outer membrane lipoprotein DUF4695 PF15766.5 CDS32799.1 - 0.12 12.6 0.3 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) TPR_8 PF13181.6 CDS32799.1 - 0.19 12.0 3.3 0.45 10.9 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS32799.1 - 8.9 6.6 12.4 17 5.7 2.0 3.9 4 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SKIP_SNW PF02731.15 CDS32800.1 - 7.8e-67 223.9 2.1 7.8e-67 223.9 2.1 2.8 3 0 0 3 3 3 1 SKIP/SNW domain I_LWEQ PF01608.17 CDS32801.1 - 2.4e-44 151.2 10.0 2.4e-44 151.2 10.0 4.1 4 1 0 4 4 4 1 I/LWEQ domain ANTH PF07651.16 CDS32801.1 - 3.1e-14 52.6 1.8 6.3e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 ANTH domain GCP_N_terminal PF17681.1 CDS32801.1 - 2.7 7.5 14.2 0.22 11.1 1.8 3.6 1 1 2 4 4 4 0 Gamma tubulin complex component N-terminal RabGAP-TBC PF00566.18 CDS32802.1 - 5.8e-45 153.6 0.4 3.6e-44 151.0 0.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fib_alpha PF08702.10 CDS32803.1 - 0.0023 18.2 6.8 0.0023 18.2 6.8 4.9 3 2 2 5 5 5 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 CDS32803.1 - 0.0025 17.9 24.0 0.0025 17.9 24.0 4.8 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein GAS PF13851.6 CDS32803.1 - 0.0063 15.9 59.5 0.12 11.7 14.6 4.6 3 1 1 4 4 4 3 Growth-arrest specific micro-tubule binding CCDC144C PF14915.6 CDS32803.1 - 0.074 12.2 62.5 0.029 13.5 24.0 4.4 3 2 1 4 4 4 0 CCDC144C protein coiled-coil region Prefoldin_2 PF01920.20 CDS32803.1 - 0.17 11.8 40.8 0.32 11.0 13.2 5.0 3 2 1 4 4 4 0 Prefoldin subunit DUF5082 PF16888.5 CDS32803.1 - 0.18 12.1 31.4 1.5 9.1 0.5 5.4 4 2 1 5 5 5 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 CDS32803.1 - 0.19 11.8 27.4 0.4 10.7 6.3 5.0 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CDS32803.1 - 0.33 11.4 53.1 0.026 14.9 8.1 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 CDS32803.1 - 0.47 7.9 49.0 0.11 10.0 13.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 CDS32803.1 - 0.72 9.1 29.4 0.87 8.9 12.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CDS32803.1 - 1.7 9.1 11.0 7.8 7.0 0.0 5.1 3 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 CDS32803.1 - 2.6 7.5 61.3 1.3 8.5 31.2 3.1 2 1 1 3 3 3 0 Intermediate filament protein Csm1_N PF18504.1 CDS32803.1 - 2.9 8.3 40.6 0.15 12.5 3.8 6.6 4 2 1 5 5 5 0 Csm1 N-terminal domain DUF4298 PF14131.6 CDS32803.1 - 9.3 6.3 14.8 0.2 11.7 1.6 4.3 4 1 0 5 5 5 0 Domain of unknown function (DUF4298) SPT2 PF08243.11 CDS32805.1 - 3.1e-14 53.4 16.4 3.1e-14 53.4 16.4 2.0 2 0 0 2 2 2 1 SPT2 chromatin protein HUN PF08729.10 CDS32805.1 - 0.0061 16.5 8.2 0.014 15.4 8.2 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain OTU PF02338.19 CDS32806.1 - 4.8e-21 75.6 0.1 3.2e-20 72.9 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDS32806.1 - 8.3e-10 38.5 0.8 5.5e-07 29.3 0.0 3.0 1 1 1 3 3 3 2 Peptidase C65 Otubain Striatin PF08232.12 CDS32806.1 - 0.095 13.3 16.5 0.15 12.7 16.5 1.2 1 0 0 1 1 1 0 Striatin family Sacchrp_dh_NADP PF03435.18 CDS32806.1 - 0.78 10.0 3.4 7.8 6.8 0.2 2.9 1 1 2 3 3 3 0 Saccharopine dehydrogenase NADP binding domain LMBR1 PF04791.16 CDS32806.1 - 8.9 5.1 6.9 11 4.8 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-Di19 PF05605.12 CDS32809.1 - 2.3e-11 43.8 4.5 5.5e-11 42.6 4.5 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 CDS32809.1 - 6.8e-10 38.6 8.5 6.8e-10 38.6 8.5 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type GAGA PF09237.11 CDS32809.1 - 0.0033 17.2 1.6 0.0082 15.9 0.0 2.4 1 1 1 2 2 2 1 GAGA factor zf-C2H2_12 PF18658.1 CDS32809.1 - 0.13 11.9 0.7 0.35 10.5 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2 PF00096.26 CDS32809.1 - 0.3 11.6 0.2 0.3 11.6 0.2 3.2 4 1 0 4 4 4 0 Zinc finger, C2H2 type Ank_2 PF12796.7 CDS32810.1 - 2e-38 130.8 19.1 3.7e-12 46.6 0.8 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS32810.1 - 7.6e-26 90.2 5.0 6.9e-09 36.1 0.1 6.4 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS32810.1 - 2.1e-25 86.0 8.4 0.0006 20.1 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDS32810.1 - 1.6e-22 78.9 13.6 0.0016 18.8 0.0 8.4 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 CDS32810.1 - 3.2e-18 65.5 11.9 0.00023 21.4 0.4 7.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) C2 PF00168.30 CDS32812.1 - 8e-07 29.3 0.5 1.9e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 C2 domain TIG PF01833.24 CDS32812.1 - 0.00077 19.5 0.0 0.0029 17.6 0.0 2.1 1 0 0 1 1 1 1 IPT/TIG domain UCH PF00443.29 CDS32813.1 - 2.7e-66 223.7 0.3 2.7e-66 223.7 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS32813.1 - 3e-20 73.1 3.1 6.7e-19 68.6 1.4 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CDS32813.1 - 0.17 11.3 2.7 2.4 7.6 0.8 2.8 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Endostatin PF06482.11 CDS32814.1 - 5.4e-40 137.8 0.0 1.6e-38 133.0 0.0 4.9 3 3 1 4 4 4 2 Collagenase NC10 and Endostatin DUF4911 PF16256.5 CDS32814.1 - 0.18 11.8 0.5 0.47 10.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) LRR_8 PF13855.6 CDS32816.1 - 2.1e-53 178.0 79.8 4.4e-10 39.2 5.5 9.5 5 2 7 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 CDS32816.1 - 7e-38 128.0 70.6 4.2e-07 30.2 2.2 12.3 5 1 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS32816.1 - 1.4e-11 44.2 33.5 0.00056 19.5 0.6 6.6 1 1 5 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 CDS32816.1 - 1e-07 31.5 57.5 3.8 8.4 0.2 16.4 18 1 1 19 19 18 3 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 CDS32816.1 - 0.00022 21.2 0.3 9.7 6.3 0.0 6.1 4 3 3 7 7 7 1 RsmF rRNA methyltransferase first C-terminal domain LRR_5 PF13306.6 CDS32816.1 - 0.00027 20.9 9.1 0.067 13.2 0.9 4.8 4 1 2 6 6 6 3 BspA type Leucine rich repeat region (6 copies) DUF1118 PF06549.12 CDS32816.1 - 0.00055 20.2 1.1 0.92 9.8 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1118) FNIP PF05725.12 CDS32816.1 - 0.0011 19.0 0.1 2.6 8.3 0.0 5.5 6 4 0 6 6 6 1 FNIP Repeat LRR_3 PF07725.12 CDS32816.1 - 0.22 11.5 9.0 30 4.7 0.4 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat CSTF_C PF14304.6 CDS32816.1 - 0.51 10.0 7.2 1.4 8.5 0.2 4.7 4 1 0 4 4 4 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 CDS32816.1 - 0.67 10.2 52.9 6.8 7.0 0.1 14.0 15 0 0 15 15 15 0 Leucine Rich repeat IL11 PF07400.11 CDS32816.1 - 3.2 7.4 11.3 1.6 8.4 0.1 4.3 4 1 1 5 5 5 0 Interleukin 11 DUF2040 PF09745.9 CDS32817.1 - 3.2e-32 111.1 16.9 3.2e-32 111.1 16.9 2.8 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DR2241 PF18069.1 CDS32817.1 - 2.5 8.0 7.2 0.36 10.7 0.8 2.6 2 0 0 2 2 2 0 DR2241 stabilising domain JAB PF01398.21 CDS32818.1 - 2.9e-10 40.1 0.0 8.5e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDS32818.1 - 4.4e-05 23.2 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Desmo_N PF06771.11 CDS32818.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus USP8_dimer PF08969.11 CDS32818.1 - 0.13 12.5 0.2 0.91 9.7 0.2 2.0 1 1 0 1 1 1 0 USP8 dimerisation domain Exo_endo_phos_2 PF14529.6 CDS32819.1 - 2.1e-11 43.7 0.1 3.5e-11 43.0 0.1 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS32819.1 - 5.8e-05 22.7 0.0 5.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF943 PF06092.12 CDS32821.1 - 0.024 14.3 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Peptidase_S41_N PF11918.8 CDS32823.2 - 0.047 13.9 0.2 0.26 11.5 0.0 2.3 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP HMG_box PF00505.19 CDS32826.2 - 2.2e-37 127.3 6.4 4.8e-20 71.8 0.3 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS32826.2 - 2e-32 111.6 8.3 1.7e-19 70.2 2.4 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 CDS32826.2 - 0.24 11.4 7.2 0.18 11.8 2.1 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box 5 PAX PF00292.18 CDS32829.1 - 7.9e-66 219.7 0.9 1.9e-65 218.4 0.9 1.7 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CDS32829.1 - 5.7e-20 70.9 1.3 1.2e-19 69.9 1.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32829.1 - 0.00025 20.9 0.1 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 CDS32829.1 - 0.0019 17.9 0.0 0.0067 16.2 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CDS32829.1 - 0.011 16.4 0.0 0.35 11.5 0.0 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 CDS32829.1 - 0.046 13.4 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 InsA C-terminal domain HAT_KAT11 PF08214.11 CDS32830.2 - 3.8e-22 79.1 0.8 7.1e-21 74.9 0.8 2.1 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 CDS32830.2 - 2.7e-18 65.8 0.5 1.3e-17 63.7 0.1 2.3 2 0 0 2 2 2 1 Bromodomain DUF902 PF06001.13 CDS32830.2 - 4.4e-07 30.3 8.4 1.5e-06 28.6 8.4 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 CDS32830.2 - 1.5e-05 25.2 0.0 4.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 KIX domain PHD PF00628.29 CDS32830.2 - 0.00024 20.9 2.0 0.00024 20.9 2.0 3.6 3 1 0 3 3 3 1 PHD-finger zf-TAZ PF02135.16 CDS32830.2 - 0.00072 20.0 5.5 0.00072 20.0 5.5 4.2 4 1 0 4 4 4 1 TAZ zinc finger ZZ PF00569.17 CDS32830.2 - 0.0061 16.4 9.1 0.0061 16.4 9.1 2.8 2 0 0 2 2 2 1 Zinc finger, ZZ type Zf_RING PF16744.5 CDS32830.2 - 0.68 10.1 9.1 0.27 11.4 0.3 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger Bromodomain PF00439.25 CDS32831.2 - 1.4e-18 66.7 0.1 3.7e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain KIX PF02172.16 CDS32831.2 - 3.5e-06 27.2 0.2 9.7e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 KIX domain zf-TAZ PF02135.16 CDS32831.2 - 8.1e-05 23.0 6.5 0.00016 22.1 5.5 1.9 2 0 0 2 2 2 1 TAZ zinc finger CAP PF00188.26 CDS32832.1 - 5.2e-26 91.9 5.5 8.3e-26 91.3 5.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSC22 PF01166.18 CDS32833.1 - 0.0097 16.2 0.1 0.026 14.8 0.1 1.6 2 0 0 2 2 2 1 TSC-22/dip/bun family CC2-LZ PF16516.5 CDS32833.1 - 0.071 13.5 0.9 0.12 12.8 0.9 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HALZ PF02183.18 CDS32833.1 - 0.072 13.3 1.0 4 7.8 0.3 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper CCDC-167 PF15188.6 CDS32833.1 - 1.4 9.3 4.7 2.3 8.6 4.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribul_P_3_epim PF00834.19 CDS32834.1 - 6.2e-62 208.5 0.0 7.1e-62 208.3 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 CDS32834.1 - 0.00077 19.3 0.0 0.0016 18.3 0.0 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Aldolase PF01081.19 CDS32834.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 KDPG and KHG aldolase ThiG PF05690.14 CDS32834.1 - 0.0078 15.6 0.2 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 CDS32834.1 - 0.013 14.8 0.1 0.03 13.7 0.0 1.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase OMPdecase PF00215.24 CDS32834.1 - 0.019 14.6 0.1 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Radical_SAM PF04055.21 CDS32834.1 - 0.13 12.7 0.1 0.82 10.0 0.0 2.2 2 1 0 3 3 3 0 Radical SAM superfamily KH_1 PF00013.29 CDS32835.1 - 4.7e-17 61.6 0.2 6.8e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 CDS32835.1 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 KH-like RNA-binding domain KH_2 PF07650.17 CDS32835.1 - 0.0011 18.8 0.6 0.0022 17.8 0.6 1.6 1 1 0 1 1 1 1 KH domain KH_4 PF13083.6 CDS32835.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 KH domain KH_1 PF00013.29 CDS32836.2 - 1.4e-38 130.5 7.4 9e-17 60.7 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CDS32836.2 - 1.5e-16 60.0 3.0 3.8e-05 23.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDS32836.2 - 9.5e-09 35.0 0.3 0.016 15.1 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CDS32836.2 - 1.1e-07 31.9 2.5 0.086 12.9 0.3 3.3 3 0 0 3 3 3 3 NusA-like KH domain R3H PF01424.22 CDS32837.1 - 0.00016 21.6 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CDS32837.1 - 0.00073 19.5 66.7 0.0024 17.9 15.8 14.1 16 1 0 16 16 16 8 NF-X1 type zinc finger Pkinase PF00069.25 CDS32838.1 - 2.6e-65 220.4 0.0 4.3e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32838.1 - 1.6e-30 106.3 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32838.1 - 0.00028 20.3 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS32838.1 - 0.0024 17.9 0.1 0.0038 17.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS32838.1 - 0.0058 15.6 0.2 0.021 13.8 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS32838.1 - 0.014 14.8 0.8 0.026 13.9 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SBDS_C PF09377.10 CDS32839.1 - 1.3e-25 89.6 0.8 1.8e-25 89.2 0.8 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CDS32839.1 - 5.1e-14 52.1 4.5 7e-13 48.5 1.7 3.1 2 1 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HTH_22 PF13309.6 CDS32839.1 - 0.019 15.0 0.5 1.1 9.4 0.2 2.9 2 0 0 2 2 2 0 HTH domain TBPIP PF07106.13 CDS32839.1 - 0.037 14.0 2.5 0.21 11.6 0.5 2.9 2 1 1 3 3 3 0 TBPIP/Hop2 winged helix domain UME PF08064.13 CDS32839.1 - 0.037 13.9 0.2 0.073 13.0 0.2 1.5 1 0 0 1 1 1 0 UME (NUC010) domain PCI PF01399.27 CDS32839.1 - 0.05 14.1 0.3 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 PCI domain MRP-S28 PF10213.9 CDS32839.1 - 0.14 12.6 1.8 0.27 11.6 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit protein LPD3 PF18798.1 CDS32839.1 - 2.6 8.3 7.2 0.42 10.9 0.6 2.7 3 1 0 3 3 3 0 Large polyvalent protein-associated domain 3 ETRAMP PF09716.10 CDS32839.1 - 7.4 6.7 7.0 35 4.5 2.6 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RUN PF02759.19 CDS32840.1 - 2.1e-09 37.5 0.2 5.3e-09 36.1 0.2 1.7 1 0 0 1 1 1 1 RUN domain YabA PF06156.13 CDS32840.1 - 0.032 14.9 0.4 0.088 13.5 0.4 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Sporozoite_P67 PF05642.11 CDS32840.1 - 6.2 4.8 7.6 8.8 4.3 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4477 PF14780.6 CDS32841.1 - 9.3e-24 84.1 5.5 1.5e-23 83.4 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Ten1_2 PF15490.6 CDS32841.1 - 3.7e-05 23.4 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit zf-TAZ PF02135.16 CDS32842.2 - 1.4e-15 57.5 58.8 2e-12 47.4 6.3 4.8 4 0 0 4 4 4 3 TAZ zinc finger HAT_KAT11 PF08214.11 CDS32842.2 - 2.4e-10 40.2 0.1 1.2e-08 34.6 0.0 2.2 1 1 0 2 2 2 1 Histone acetylation protein ZZ PF00569.17 CDS32842.2 - 7.3e-06 25.7 7.0 7.3e-06 25.7 7.0 5.6 5 0 0 5 5 5 1 Zinc finger, ZZ type DUF902 PF06001.13 CDS32842.2 - 1.2e-05 25.7 7.0 5.9e-05 23.5 6.2 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) PHD PF00628.29 CDS32842.2 - 6.6e-05 22.7 3.0 6.6e-05 22.7 3.0 5.1 2 1 2 4 4 4 1 PHD-finger KIX PF02172.16 CDS32842.2 - 0.0037 17.5 0.0 0.0087 16.3 0.0 1.6 1 0 0 1 1 1 1 KIX domain DUF4428 PF14471.6 CDS32842.2 - 0.018 14.9 6.3 2.6 8.1 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AAA PF00004.29 CDS32843.1 - 1.1e-11 45.2 0.0 3.7e-11 43.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDS32843.1 - 1e-06 28.8 0.0 9.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CDS32843.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDS32843.1 - 3e-05 24.0 0.0 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDS32843.1 - 6.5e-05 23.4 0.0 0.00057 20.3 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 CDS32843.1 - 0.00097 19.4 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS32843.1 - 0.0011 19.1 0.1 0.0035 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDS32843.1 - 0.0017 18.9 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS32843.1 - 0.0018 18.6 0.0 0.0061 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CDS32843.1 - 0.0037 17.6 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 CDS32843.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDS32843.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 CDS32843.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CDS32843.1 - 0.034 14.6 0.0 0.17 12.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain dNK PF01712.19 CDS32843.1 - 0.057 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 CDS32843.1 - 0.17 11.7 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CDS32843.1 - 0.2 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pou PF00157.17 CDS32844.1 - 5.5e-17 61.5 0.2 1e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CDS32844.1 - 2.3e-10 40.1 0.2 4.2e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32844.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_31 PF13560.6 CDS32844.1 - 0.026 14.9 0.6 0.42 11.0 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.7 CDS32844.1 - 0.1 12.6 0.1 0.41 10.7 0.1 2.0 3 0 0 3 3 3 0 Helix-turn-helix domain Cyclin_N PF00134.23 CDS32846.1 - 1.1e-11 44.6 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain IRK PF01007.20 CDS32846.1 - 0.06 13.2 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain COesterase PF00135.28 CDS32848.1 - 3.3e-24 85.7 0.0 6.9e-24 84.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDS32848.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ubiquitin PF00240.23 CDS32849.1 - 1.6e-42 143.1 1.0 1.8e-10 40.4 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 CDS32849.1 - 4.7e-30 103.2 0.0 5.8e-08 32.5 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDS32849.1 - 1.3e-12 47.6 6.2 0.00094 19.2 0.0 6.2 4 3 3 7 7 7 3 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDS32849.1 - 2.6e-06 27.8 5.5 0.12 12.8 0.3 5.1 4 3 0 4 4 4 2 Ubiquitin-like domain UN_NPL4 PF11543.8 CDS32849.1 - 1.1e-05 25.8 0.7 0.03 14.8 0.1 4.2 4 0 0 4 4 4 1 Nuclear pore localisation protein NPL4 Ubiquitin_5 PF18037.1 CDS32849.1 - 1.8e-05 25.0 0.0 0.34 11.3 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDS32849.1 - 9.2e-05 22.5 0.0 7.9 6.6 0.0 4.4 3 2 1 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 CDS32849.1 - 0.042 14.1 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 TUG ubiquitin-like domain YukD PF08817.10 CDS32849.1 - 0.077 13.7 0.1 11 6.7 0.0 3.4 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD FeoA PF04023.14 CDS32849.1 - 0.089 13.1 0.0 10 6.5 0.0 3.6 2 2 2 4 4 4 0 FeoA domain Rer1 PF03248.13 CDS32850.1 - 1.6e-53 181.0 16.2 2.3e-38 131.6 5.5 2.0 1 1 1 2 2 2 2 Rer1 family DUF1980 PF09323.10 CDS32850.1 - 0.062 13.2 0.6 0.062 13.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2208 PF09973.9 CDS32850.1 - 1.4 8.5 10.1 0.077 12.6 4.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RNA_pol_Rpc82 PF05645.13 CDS32851.1 - 1.6e-06 28.1 0.3 0.04 13.7 0.0 2.7 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 DUF4191 PF13829.6 CDS32851.1 - 0.0026 17.2 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) ATF7IP_BD PF16788.5 CDS32851.1 - 0.0027 17.8 0.2 0.0049 17.0 0.2 1.3 1 0 0 1 1 1 1 ATF-interacting protein binding domain Spc7 PF08317.11 CDS32851.1 - 0.043 12.7 0.4 0.064 12.1 0.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein nsp7 PF08716.10 CDS32851.1 - 0.2 12.3 0.6 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 nsp7 replicase Apolipoprotein PF01442.18 CDS32851.1 - 0.21 11.5 4.7 0.13 12.1 2.5 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3437 PF11919.8 CDS32852.1 - 1.9e-24 85.4 0.0 7.8e-24 83.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 CDS32852.1 - 1.4e-12 47.0 1.5 4.4e-07 28.9 0.1 3.7 3 1 0 3 3 3 3 Proteasome-substrate-size regulator, mid region Integrin_alpha2 PF08441.12 CDS32853.2 - 1.4e-25 90.1 0.0 2.2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CDS32853.2 - 9.4e-16 57.6 33.5 4.1e-07 30.0 0.6 5.8 7 1 0 7 7 7 4 FG-GAP repeat VCBS PF13517.6 CDS32853.2 - 9.3e-11 42.2 9.4 7.5e-07 29.6 1.4 5.6 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Baculo_LEF-10 PF07206.11 CDS32853.2 - 0.2 11.9 0.3 37 4.6 0.0 2.5 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) EF-hand_5 PF13202.6 CDS32853.2 - 3.6 7.2 4.5 30 4.3 0.5 3.2 2 0 0 2 2 2 0 EF hand S10_plectin PF03501.15 CDS32854.1 - 1.3e-37 127.7 0.1 1.6e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 CDS32854.1 - 0.13 12.2 0.6 0.4 10.6 0.6 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RRM_1 PF00076.22 CDS32855.2 - 3.7e-13 49.1 0.0 7.5e-05 22.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDS32855.2 - 2.6e-09 36.9 0.0 0.099 12.7 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif SesA PF17107.5 CDS32855.2 - 0.17 12.1 0.1 1.8 8.8 0.1 2.2 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Homeobox_KN PF05920.11 CDS32856.2 - 1.8e-15 56.5 0.0 3.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS32856.2 - 3.8e-07 29.8 0.9 7.4e-07 28.9 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS32857.1 - 1.8e-06 27.7 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 CDS32859.1 - 1.7e-14 53.4 0.1 4.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDS32859.1 - 0.00013 21.9 0.0 0.053 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 CDS32859.1 - 0.0044 17.0 0.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDS32859.1 - 0.0068 16.2 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Siva PF05458.12 CDS32859.1 - 0.031 14.0 5.4 0.086 12.5 5.4 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) JMY PF15871.5 CDS32859.1 - 0.2 10.9 1.0 0.36 10.1 1.0 1.4 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein zf-B_box PF00643.24 CDS32859.1 - 0.49 10.6 20.5 2.1 8.6 7.5 2.4 1 1 1 2 2 2 0 B-box zinc finger RRM_1 PF00076.22 CDS32860.2 - 4.5e-21 74.4 3.4 0.00019 21.2 0.0 8.0 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDS32860.2 - 1.9e-08 34.2 2.6 0.069 13.2 0.0 6.3 6 0 0 6 6 6 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS32860.2 - 9.1e-08 32.1 4.4 1.1 9.3 0.0 6.5 7 0 0 7 7 7 4 RNA binding motif BAF250_C PF12031.8 CDS32861.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Pkinase PF00069.25 CDS32862.1 - 5.6e-59 199.7 0.0 9.9e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32862.1 - 4.2e-32 111.4 0.0 6.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CDS32862.1 - 0.15 11.7 0.1 0.46 10.2 0.1 1.9 1 0 0 1 1 1 0 EF hand Pet100 PF09803.9 CDS32862.1 - 6.9 7.3 7.3 13 6.4 0.3 3.1 3 0 0 3 3 3 0 Pet100 ERK-JNK_inhib PF15002.6 CDS32863.1 - 2e-23 83.1 1.8 2.3e-23 82.9 1.8 1.1 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor RNA_pol_Rpb8 PF03870.15 CDS32863.1 - 0.04 14.1 0.2 0.068 13.4 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb8 Nore1-SARAH PF16517.5 CDS32865.1 - 5.8e-07 29.3 5.4 1.3e-06 28.2 5.4 1.6 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain C1_1 PF00130.22 CDS32865.1 - 0.00039 20.2 8.1 0.00074 19.4 8.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Desmo_N PF06771.11 CDS32866.2 - 0.0095 16.3 0.1 0.048 14.0 0.1 2.2 2 0 0 2 2 2 1 Viral Desmoplakin N-terminus BTB PF00651.31 CDS32867.1 - 4.5e-16 59.1 0.4 1.8e-06 28.2 0.0 3.3 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 CDS32867.1 - 1.9e-07 31.1 0.7 1.9e-07 31.1 0.7 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Pkinase_fungal PF17667.1 CDS32867.1 - 0.11 11.2 9.7 0.028 13.2 4.3 2.0 2 0 0 2 2 2 0 Fungal protein kinase HECT PF00632.25 CDS32868.1 - 1.2e-23 84.0 0.1 1.3e-23 83.9 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CDS32869.2 - 2.9e-46 158.4 0.5 8.1e-26 91.2 0.1 2.0 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF5388 PF17363.2 CDS32870.1 - 0.0089 16.2 0.2 0.78 10.0 0.0 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5388) DUF4487 PF14868.6 CDS32870.1 - 0.021 13.7 0.1 0.028 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) tRNA-synt_1c PF00749.21 CDS32871.2 - 3.8e-105 351.2 0.0 4.8e-105 350.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDS32871.2 - 8.2e-45 152.8 0.0 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CDS32871.2 - 4.1e-11 43.6 0.2 7.8e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF4187 PF13821.6 CDS32872.1 - 4.1e-20 71.3 0.4 1e-19 70.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CDS32872.1 - 7.2e-13 48.2 2.0 1.4e-12 47.2 2.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDS32872.1 - 0.0011 19.0 2.4 0.0016 18.5 1.7 1.7 1 1 0 1 1 1 1 G-patch domain Citrate_bind PF16114.5 CDS32875.1 - 2.8e-83 277.8 0.0 4.3e-83 277.2 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CDS32875.1 - 6.4e-17 61.6 0.0 1.5e-15 57.2 0.0 2.6 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CDS32875.1 - 3.1e-13 49.8 0.1 7.8e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_2 PF08442.10 CDS32875.1 - 8.8e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 CDS32875.1 - 0.011 16.4 0.0 0.03 15.0 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Succ_CoA_lig PF13607.6 CDS32875.1 - 0.15 11.8 0.1 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Hepatitis_core PF00906.20 CDS32875.1 - 0.7 9.4 7.6 1.2 8.6 7.6 1.3 1 0 0 1 1 1 0 Hepatitis core antigen Histone_H2A_C PF16211.5 CDS32876.1 - 1.9e-12 46.7 0.1 4.5e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CDS32876.1 - 1.1e-11 45.2 0.0 1.5e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS32876.1 - 7.6e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C48 PF02902.19 CDS32877.1 - 4.7e-39 134.5 0.7 7.7e-39 133.8 0.7 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain EnY2 PF10163.9 CDS32878.1 - 4.3e-16 59.1 0.4 9.9e-16 57.9 0.4 1.6 1 1 0 1 1 1 1 Transcription factor e(y)2 EGF PF00008.27 CDS32879.1 - 5.1e-05 23.5 37.9 0.00052 20.3 8.5 3.4 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 CDS32879.1 - 0.00023 21.3 3.8 0.00023 21.3 3.8 3.4 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 CDS32879.1 - 0.00028 21.4 25.5 0.032 14.9 4.1 3.7 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_CA PF07645.15 CDS32879.1 - 0.01 16.0 3.1 0.01 16.0 3.1 3.4 3 0 0 3 3 3 0 Calcium-binding EGF domain EGF_2 PF07974.13 CDS32879.1 - 1.9 8.9 39.2 0.33 11.3 11.0 3.4 3 0 0 3 3 3 0 EGF-like domain AAA PF00004.29 CDS32880.1 - 1.6e-50 170.9 0.0 1.6e-39 135.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDS32880.1 - 4.9e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CDS32880.1 - 3.2e-07 31.0 0.0 0.044 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDS32880.1 - 1.6e-06 28.7 0.0 0.0084 16.5 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CDS32880.1 - 3.4e-06 27.4 0.2 0.0046 17.2 0.1 3.9 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 CDS32880.1 - 5.3e-06 25.9 0.1 0.06 12.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 CDS32880.1 - 1.5e-05 25.0 0.2 0.0017 18.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDS32880.1 - 3.6e-05 23.9 0.0 9.9e-05 22.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CDS32880.1 - 4.4e-05 23.3 0.1 0.0097 15.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CDS32880.1 - 0.00015 21.6 0.3 0.056 13.2 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 CDS32880.1 - 0.00027 21.1 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CDS32880.1 - 0.0003 20.8 0.0 0.061 13.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CDS32880.1 - 0.00032 20.1 0.7 0.0078 15.6 0.2 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 CDS32880.1 - 0.00059 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 CDS32880.1 - 0.001 18.7 0.1 1.3 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 CDS32880.1 - 0.0011 18.3 0.1 0.0059 16.0 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_3 PF07726.11 CDS32880.1 - 0.0012 18.7 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDS32880.1 - 0.0021 18.4 0.0 0.045 14.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CDS32880.1 - 0.0036 17.2 0.4 3 7.7 0.0 3.8 4 0 0 4 4 4 1 NACHT domain CDC48_2 PF02933.17 CDS32880.1 - 0.0042 16.8 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 CDS32880.1 - 0.0045 17.0 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 CDS32880.1 - 0.006 15.7 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CDS32880.1 - 0.0063 15.8 0.8 0.16 11.2 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.6 CDS32880.1 - 0.012 15.8 0.0 7.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDS32880.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Hydin_ADK PF17213.3 CDS32880.1 - 0.02 15.2 0.1 0.47 10.7 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IPT PF01745.16 CDS32880.1 - 0.021 14.2 0.1 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase IstB_IS21 PF01695.17 CDS32880.1 - 0.022 14.5 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 CDS32880.1 - 0.035 14.0 0.2 10 5.9 0.1 3.4 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CDS32880.1 - 0.062 13.0 0.0 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CDS32880.1 - 0.068 13.7 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter TniB PF05621.11 CDS32880.1 - 0.075 12.4 0.2 32 3.9 0.0 3.4 2 1 1 3 3 3 0 Bacterial TniB protein GTPase_binding PF09027.10 CDS32880.1 - 0.086 12.8 0.0 8.5 6.4 0.0 2.5 2 0 0 2 2 2 0 GTPase binding AAA_11 PF13086.6 CDS32880.1 - 0.093 12.5 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDS32880.1 - 0.095 12.4 0.1 0.29 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 CDS32880.1 - 0.16 11.4 0.0 3.6 6.9 0.0 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 CDS32880.1 - 0.25 10.5 0.2 6.1 6.0 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CDS32880.1 - 1.8 8.9 4.5 1.5 9.2 0.1 3.0 4 1 1 5 5 3 0 AAA domain Tropomyosin PF00261.20 CDS32881.1 - 1.7e-72 243.6 68.6 1.5e-40 139.0 26.7 4.0 3 1 1 4 4 4 4 Tropomyosin Tropomyosin_1 PF12718.7 CDS32881.1 - 2.4e-16 60.2 17.3 2.4e-16 60.2 17.3 5.0 4 1 0 4 4 4 2 Tropomyosin like XhlA PF10779.9 CDS32881.1 - 0.068 13.4 0.2 0.068 13.4 0.2 6.9 5 1 1 6 6 6 0 Haemolysin XhlA Holin_BhlA PF10960.8 CDS32881.1 - 0.071 13.1 17.7 0.34 10.9 0.6 4.9 5 0 0 5 5 5 0 BhlA holin family ATG16 PF08614.11 CDS32881.1 - 0.19 11.9 60.9 0.58 10.4 1.4 5.0 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) NPBW PF15180.6 CDS32881.1 - 0.38 10.6 1.5 0.98 9.3 0.1 2.4 2 0 0 2 2 2 0 Neuropeptides B and W DUF2721 PF11026.8 CDS32881.1 - 0.6 10.0 5.8 3.8 7.4 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) BLOC1S3 PF15753.5 CDS32881.1 - 0.82 9.8 12.7 3.3 7.8 0.3 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 T3SSipB PF16535.5 CDS32881.1 - 1.2 9.6 26.3 2.2 8.7 0.2 4.4 4 1 1 5 5 5 0 Type III cell invasion protein SipB Spc7 PF08317.11 CDS32881.1 - 2.8 6.7 52.2 0.055 12.3 8.1 3.7 3 2 0 3 3 3 0 Spc7 kinetochore protein Uds1 PF15456.6 CDS32881.1 - 7.1 6.8 39.5 0.32 11.2 6.1 4.9 3 1 1 4 4 4 0 Up-regulated During Septation SLX9 PF15341.6 CDS32882.1 - 0.053 13.9 6.3 0.064 13.7 2.1 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 KH_10 PF17905.1 CDS32882.1 - 0.061 13.8 0.2 0.13 12.7 0.2 1.6 1 1 0 1 1 1 0 GLD-3 KH domain 5 zf-ZPR1 PF03367.13 CDS32882.1 - 0.31 10.9 5.2 0.2 11.5 0.2 2.5 1 1 0 2 2 2 0 ZPR1 zinc-finger domain DUF4208 PF13907.6 CDS32882.1 - 1.1 9.8 6.1 20 5.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Syntaxin-6_N PF09177.11 CDS32882.1 - 3.1 8.4 8.7 34 5.1 0.3 3.7 3 1 1 4 4 4 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 CDS32882.1 - 5 7.7 10.4 7.2 7.2 1.3 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF848 PF05852.11 CDS32882.1 - 6.7 6.8 7.2 15 5.6 0.4 2.9 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Syntaxin_2 PF14523.6 CDS32883.1 - 0.00054 20.3 3.4 0.0015 18.8 0.5 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SSFA2_C PF14723.6 CDS32883.1 - 0.0059 16.5 1.6 0.47 10.3 0.0 3.4 1 1 2 3 3 3 1 Sperm-specific antigen 2 C-terminus CAMP_factor PF07373.11 CDS32883.1 - 0.084 12.5 7.6 0.14 11.8 2.5 2.8 2 1 1 3 3 3 0 CAMP factor (Cfa) Pyridox_ox_2 PF12900.7 CDS32883.1 - 0.14 12.1 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TMCO5 PF14992.6 CDS32883.1 - 0.94 9.0 5.4 1.6 8.3 5.4 1.3 1 0 0 1 1 1 0 TMCO5 family Cauli_AT PF03233.13 CDS32883.1 - 2.4 8.1 9.9 10 6.0 0.0 3.8 3 1 1 4 4 4 0 Aphid transmission protein COG5 PF10392.9 CDS32883.1 - 3.5 7.8 9.3 3.8 7.7 4.2 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 ALMT PF11744.8 CDS32883.1 - 3.8 6.2 9.7 2.3 6.9 5.5 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter AATF-Che1 PF13339.6 CDS32883.1 - 6.9 7.3 9.8 12 6.6 7.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TRPM_tetra PF16519.5 CDS32885.1 - 0.11 12.7 3.5 0.16 12.1 1.0 2.8 2 1 0 2 2 2 0 Tetramerisation domain of TRPM CLZ PF16526.5 CDS32885.1 - 0.12 12.8 1.8 6 7.3 0.3 3.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0184 PF03670.13 CDS32885.1 - 0.22 12.0 3.4 18 5.8 0.3 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) GLE1 PF07817.13 CDS32885.1 - 0.49 9.6 5.7 1.8 7.7 5.7 2.1 1 0 0 1 1 1 0 GLE1-like protein Fzo_mitofusin PF04799.13 CDS32885.1 - 0.64 9.6 8.1 0.68 9.5 4.8 2.8 1 1 1 2 2 2 0 fzo-like conserved region DUF3958 PF13125.6 CDS32885.1 - 0.74 10.0 6.4 8.5 6.6 3.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Syntaxin-6_N PF09177.11 CDS32885.1 - 0.75 10.4 10.1 2.1 9.0 4.1 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Spectrin PF00435.21 CDS32885.1 - 1.4 9.4 7.8 4.2 7.9 5.3 3.0 2 1 1 3 3 3 0 Spectrin repeat CxxCxxCC PF03692.15 CDS32885.1 - 3.6 8.4 7.3 6.8 7.4 0.2 3.2 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain Snapin_Pallidin PF14712.6 CDS32885.1 - 6.1 7.3 20.4 5.9 7.4 4.0 4.0 2 1 1 3 3 3 0 Snapin/Pallidin Sigma70_r1_1 PF03979.14 CDS32886.1 - 0.087 12.9 3.5 0.48 10.5 0.3 3.1 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 Neuropep_like PF15161.6 CDS32886.1 - 0.61 9.8 1.8 27 4.5 0.0 3.2 4 0 0 4 4 4 0 Neuropeptide-like PTPA PF03095.15 CDS32886.1 - 0.67 9.4 15.1 0.59 9.5 6.1 4.0 2 1 1 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein FUSC PF04632.12 CDS32886.1 - 1.2 7.6 5.9 0.22 10.0 1.3 1.9 2 1 1 3 3 3 0 Fusaric acid resistance protein family V-ATPase_H_N PF03224.14 CDS32887.1 - 1.2e-47 162.8 9.9 2e-47 162.0 7.9 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CDS32887.1 - 6.6e-45 152.0 0.2 6.6e-45 152.0 0.2 2.2 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 CDS32887.1 - 0.00011 22.1 0.2 0.19 11.9 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CDS32887.1 - 0.00011 22.1 0.3 0.004 17.3 0.0 3.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CDS32887.1 - 0.00017 21.9 0.0 0.015 15.6 0.0 3.2 3 1 1 4 4 4 1 HEAT repeats Arm_2 PF04826.13 CDS32887.1 - 0.00046 19.7 0.0 0.0015 18.0 0.0 1.8 1 0 0 1 1 1 1 Armadillo-like HEAT_EZ PF13513.6 CDS32887.1 - 0.088 13.3 0.1 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 HEAT-like repeat FSH1 PF03959.13 CDS32888.1 - 1.4e-48 165.4 0.0 1.9e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CDS32888.1 - 0.0053 16.1 0.0 0.014 14.7 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Tubulin PF00091.25 CDS32889.1 - 3e-48 164.7 0.0 5.5e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS32889.1 - 8.2e-30 103.6 0.1 1.4e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Pkinase PF00069.25 CDS32890.2 - 1.7e-31 109.6 0.0 1.1e-21 77.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32890.2 - 1.9e-10 40.5 0.0 1.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Cytochrom_C PF00034.21 CDS32892.1 - 5.9e-11 43.4 0.1 9.4e-11 42.7 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDS32892.1 - 1.5e-06 28.4 0.4 4.9e-06 26.8 0.4 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDS32892.1 - 0.00024 20.8 0.2 0.00042 20.0 0.2 1.7 1 1 0 1 1 1 1 Cytochrome c-550 domain Melibiase_2 PF16499.5 CDS32893.1 - 4e-115 383.9 1.2 4.9e-115 383.6 1.2 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_2_C PF17450.2 CDS32893.1 - 9e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase_C PF17801.1 CDS32893.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CDS32893.1 - 0.00023 20.2 0.0 0.00044 19.3 0.0 1.4 1 0 0 1 1 1 1 Melibiase PSS PF03034.15 CDS32894.1 - 3.2e-102 342.0 18.0 5.2e-102 341.3 18.0 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase Pkinase PF00069.25 CDS32895.1 - 5.2e-49 167.0 0.0 4.9e-48 163.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32895.1 - 2e-21 76.4 0.0 2.2e-20 73.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32895.1 - 0.0089 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS32895.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDS32895.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAR2 PF05282.11 CDS32896.1 - 1.1e-64 219.1 0.0 1.5e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DENN PF02141.21 CDS32897.1 - 5.8e-34 117.7 5.4 9.5e-34 117.0 4.4 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 CDS32897.1 - 4.2e-06 27.4 0.2 1.6e-05 25.5 0.2 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CDS32897.1 - 0.00095 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 dDENN domain DUF2464 PF10240.9 CDS32897.1 - 0.0081 15.8 1.1 0.15 11.6 0.0 3.1 3 1 1 4 4 4 1 Multivesicular body subunit 12 SPA PF08616.10 CDS32897.1 - 0.18 11.8 1.0 0.4 10.7 0.4 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis Claudin_2 PF13903.6 CDS32898.1 - 0.00087 19.1 6.5 0.0015 18.4 6.5 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Fucose_iso_N2 PF07882.12 CDS32899.1 - 0.053 13.1 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain RhoGAP PF00620.27 CDS32900.1 - 1.6e-20 73.5 0.0 4.3e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain LRRFIP PF09738.9 CDS32901.1 - 6.4e-06 25.9 4.2 7.1e-06 25.7 4.2 1.1 1 0 0 1 1 1 1 LRRFIP family ZapB PF06005.12 CDS32901.1 - 3.5e-05 24.2 9.2 0.00064 20.1 9.0 2.3 1 1 0 1 1 1 1 Cell division protein ZapB KASH_CCD PF14662.6 CDS32901.1 - 0.0015 18.4 7.1 0.0023 17.8 7.1 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 CDS32901.1 - 0.0098 16.1 8.3 0.34 11.2 4.5 2.2 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein HALZ PF02183.18 CDS32901.1 - 0.017 15.3 9.2 0.084 13.1 1.9 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 CDS32901.1 - 0.018 15.1 9.0 1.8 8.7 0.3 3.4 1 1 2 3 3 3 0 Basic region leucine zipper DUF1640 PF07798.11 CDS32901.1 - 0.018 15.1 4.9 0.026 14.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TSC22 PF01166.18 CDS32901.1 - 0.02 15.2 6.5 0.36 11.2 2.8 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Rootletin PF15035.6 CDS32901.1 - 0.024 14.7 7.8 0.045 13.8 7.1 1.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 CDS32901.1 - 0.024 14.7 8.5 0.17 12.0 1.3 2.7 1 1 2 3 3 3 0 bZIP transcription factor Uso1_p115_C PF04871.13 CDS32901.1 - 0.029 14.7 2.7 0.046 14.1 2.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fmp27_WPPW PF10359.9 CDS32901.1 - 0.03 13.2 2.4 0.037 12.9 2.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.8 CDS32901.1 - 0.053 12.8 4.5 0.073 12.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Noggin PF05806.12 CDS32901.1 - 0.085 12.8 0.8 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 Noggin YabA PF06156.13 CDS32901.1 - 0.11 13.2 6.9 1.1 10.0 5.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 CDS32901.1 - 0.14 11.9 8.9 1.5 8.6 1.1 2.5 1 1 1 2 2 2 0 Septum formation initiator HAP1_N PF04849.13 CDS32901.1 - 0.16 11.2 9.7 0.44 9.7 9.4 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 CDS32901.1 - 0.2 10.5 5.5 0.25 10.2 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDS32901.1 - 0.23 11.5 4.1 0.34 11.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NRBF2 PF08961.10 CDS32901.1 - 0.27 10.8 8.4 2.5 7.6 2.5 2.9 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator DivIVA PF05103.13 CDS32901.1 - 0.49 10.5 4.8 6.7 6.8 0.7 2.2 1 1 1 2 2 2 0 DivIVA protein DUF2205 PF10224.9 CDS32901.1 - 0.52 10.3 7.4 2.2 8.3 3.8 2.5 1 1 1 2 2 2 0 Short coiled-coil protein Spc24 PF08286.11 CDS32901.1 - 0.62 10.3 7.6 1.5 9.1 7.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Macoilin PF09726.9 CDS32901.1 - 0.7 8.4 5.6 0.84 8.1 5.6 1.1 1 0 0 1 1 1 0 Macoilin family MctB PF11382.8 CDS32901.1 - 0.72 9.5 6.7 2.9 7.5 1.0 2.2 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB DUF3552 PF12072.8 CDS32901.1 - 0.81 9.1 7.2 1 8.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF5094 PF17015.5 CDS32901.1 - 0.95 9.5 8.3 1.4 9.0 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Cnn_1N PF07989.11 CDS32901.1 - 0.99 9.6 7.2 2.2 8.5 6.9 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 CDS32901.1 - 5 7.5 9.9 2.1 8.7 3.8 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 CDS32901.1 - 6.1 6.9 11.9 85 3.2 11.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Peptidase_S24 PF00717.23 CDS32902.1 - 3.1e-09 36.7 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rav1p_C PF12234.8 CDS32903.1 - 1e-57 196.0 0.0 9.2e-48 163.1 0.0 2.7 2 1 0 2 2 2 2 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 CDS32903.1 - 0.00022 21.4 0.7 7 7.0 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS32903.1 - 0.001 19.8 13.4 0.47 11.4 0.0 6.8 6 0 0 6 6 6 2 WD domain, G-beta repeat RhoGAP PF00620.27 CDS32906.1 - 1.2e-19 70.7 0.0 8.1e-19 67.9 0.0 2.4 1 1 0 1 1 1 1 RhoGAP domain PDZ PF00595.24 CDS32906.1 - 4e-09 36.7 0.1 9.1e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS32906.1 - 1.4e-06 28.0 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS32906.1 - 0.0041 17.4 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_C48 PF02902.19 CDS32907.2 - 7.1e-36 124.1 1.6 1.4e-35 123.1 1.6 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CLP1_P PF16575.5 CDS32907.2 - 2.5e-32 112.2 0.0 1.3e-31 109.9 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CDS32907.2 - 4e-19 68.6 0.0 8.8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CDS32907.2 - 2.1e-11 44.3 0.0 5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 CDS32907.2 - 0.0022 17.8 0.1 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CDS32907.2 - 0.016 15.8 0.1 0.25 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain TFIIIC_delta PF12657.7 CDS32908.1 - 1e-06 28.8 0.0 6.8e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term Nuc_sug_transp PF04142.15 CDS32909.1 - 2e-42 145.5 27.4 6.5e-42 143.8 27.4 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter DPPIV_N PF00930.21 CDS32910.2 - 1.2e-06 27.6 0.3 0.00081 18.2 0.2 2.4 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CDS32910.2 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase PF00069.25 CDS32911.1 - 4.4e-60 203.3 0.0 9.2e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32911.1 - 7.9e-60 202.3 0.0 1.2e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS32911.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CDS32911.1 - 0.078 12.6 0.1 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TSP_NTD PF17804.1 CDS32911.1 - 0.24 11.7 2.9 0.62 10.3 2.9 1.7 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Exonuc_VII_L PF02601.15 CDS32911.1 - 5.7 6.4 8.9 21 4.6 0.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit LysM PF01476.20 CDS32912.1 - 3.8e-09 36.5 0.1 5.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 LysM domain Adaptin_N PF01602.20 CDS32913.1 - 7.4e-142 473.6 19.1 1e-141 473.1 19.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDS32913.1 - 2.8e-20 73.0 10.1 6.6e-18 65.3 0.1 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 CDS32913.1 - 2.8e-18 66.6 0.0 7.3e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal SH2 PF00017.24 CDS32913.1 - 2e-15 56.6 0.0 1.1e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 SH2 domain Pkinase_Tyr PF07714.17 CDS32913.1 - 8.2e-13 48.2 0.0 1.1e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 CDS32913.1 - 8.1e-10 38.2 0.0 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain HEAT_2 PF13646.6 CDS32913.1 - 2.1e-08 34.4 7.5 2.4e-05 24.6 0.4 5.6 3 2 4 7 7 7 1 HEAT repeats SH3_9 PF14604.6 CDS32913.1 - 2.2e-08 33.8 0.0 4.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 CDS32913.1 - 1.3e-07 31.2 0.0 3.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain SH3_2 PF07653.17 CDS32913.1 - 2.1e-05 24.1 0.0 7.1e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain HEAT PF02985.22 CDS32913.1 - 0.00016 21.6 6.3 2.9 8.4 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 CDS32913.1 - 0.023 15.2 0.3 23 5.6 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat Mto2_bdg PF12808.7 CDS32915.1 - 0.069 13.5 0.1 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sec10 PF07393.11 CDS32916.1 - 1.9e-76 258.1 9.8 1.1e-59 202.7 4.9 3.1 2 1 0 2 2 2 2 Exocyst complex component Sec10 RTTN_N PF14726.6 CDS32916.1 - 0.08 13.8 1.2 1.2 10.0 0.1 3.3 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Pkinase_Tyr PF07714.17 CDS32917.2 - 4.3e-42 144.2 0.0 2.2e-35 122.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS32917.2 - 3.4e-15 56.1 0.0 1.3e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain SNF2_N PF00176.23 CDS32923.1 - 2.8e-57 194.0 0.1 5.6e-57 193.0 0.1 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS32923.1 - 8.8e-16 58.2 0.1 2.1e-14 53.8 0.0 3.1 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS32923.1 - 2.2e-12 47.3 0.7 1.3e-10 41.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CDS32923.1 - 0.001 18.4 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 CDS32923.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-H3C2 PF16721.5 CDS32924.2 - 0.044 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Cep57_CLD_2 PF14197.6 CDS32924.2 - 0.5 10.5 6.4 0.43 10.7 3.5 2.4 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 CDS32924.2 - 3.7 7.3 12.7 0.95 9.3 7.0 2.6 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH TolA_bind_tri PF16331.5 CDS32924.2 - 5.2 7.2 7.2 2.4 8.3 3.0 2.5 2 1 1 3 3 3 0 TolA binding protein trimerisation WD40 PF00400.32 CDS32926.1 - 0.00015 22.5 10.0 1.4 9.9 0.1 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS32926.1 - 0.013 15.7 0.0 0.15 12.4 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CDS32926.1 - 0.051 12.8 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pox_A28 PF04584.14 CDS32926.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A28 family MMgT PF10270.9 CDS32927.1 - 4.1e-13 49.5 0.0 4.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter PGPGW PF09656.10 CDS32927.1 - 0.21 11.1 2.6 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF4061 PF13270.6 CDS32928.1 - 7.4e-29 99.9 1.3 9.2e-29 99.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Cep57_MT_bd PF06657.13 CDS32928.1 - 0.14 12.6 2.2 4.1 7.9 2.2 2.3 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Pkinase PF00069.25 CDS32929.1 - 1.3e-32 113.3 0.0 2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS32929.1 - 1.9e-11 43.7 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Macoilin PF09726.9 CDS32929.1 - 2.4 6.6 10.6 8.6 4.8 11.5 1.4 2 0 0 2 2 2 0 Macoilin family Btz PF09405.10 CDS32931.1 - 5e-16 59.2 7.5 5e-16 59.2 7.5 4.6 6 1 0 6 6 6 1 CASC3/Barentsz eIF4AIII binding DUF3480 PF11979.8 CDS32933.1 - 1e-21 77.4 0.0 3.9e-21 75.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.21 CDS32933.1 - 5.5e-19 68.1 2.0 1.5e-18 66.6 2.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDS32933.1 - 0.29 11.4 3.8 0.64 10.3 1.9 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Zn_ribbon_SprT PF17283.2 CDS32933.1 - 6.2 6.8 8.5 17 5.4 8.5 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Rsm22 PF09243.10 CDS32934.1 - 6.5e-40 137.1 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 cwf21 PF08312.12 CDS32934.1 - 9.5 6.5 8.5 21 5.3 1.0 2.5 2 0 0 2 2 2 0 cwf21 domain Vta1 PF04652.16 CDS32935.1 - 5.6e-39 133.4 0.9 7.5e-39 133.0 0.9 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CDS32935.1 - 3.7e-17 61.7 2.2 4.1e-15 55.2 0.6 2.6 2 0 0 2 2 2 2 Vta1 C-terminal domain Miff PF05644.11 CDS32936.1 - 1.7e-05 24.6 2.4 0.00048 19.9 2.2 2.3 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff EIF_2_alpha PF07541.12 CDS32937.1 - 7.3e-30 103.4 0.1 3.7e-29 101.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CDS32937.1 - 3e-11 43.5 0.6 7.1e-11 42.3 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Merozoite_SPAM PF07133.11 CDS32937.1 - 0.6 10.1 26.9 1.1 9.2 26.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 CDS32937.1 - 3.4 5.8 20.4 4.6 5.3 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family XPG_N PF00752.17 CDS32938.1 - 8.7e-33 112.8 0.0 1.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDS32938.1 - 1.6e-31 108.5 0.0 3.1e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CDS32938.1 - 1.5e-05 25.5 0.0 5.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CDS32938.1 - 0.057 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif XPG_I_2 PF12813.7 CDS32938.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing 7tm_1 PF00001.21 CDS32939.2 - 2.1e-11 43.6 16.7 3.3e-11 43.0 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS32939.2 - 7.2e-06 25.8 22.0 1.3e-05 25.0 22.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 CDS32939.2 - 1.1e-05 24.9 4.2 1.1e-05 24.9 4.2 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.9 CDS32939.2 - 0.00055 19.4 19.8 0.0021 17.5 19.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CDS32939.2 - 0.02 14.6 12.0 0.1 12.3 12.0 2.0 1 1 0 1 1 1 0 Olfactory receptor Exo_endo_phos_2 PF14529.6 CDS32940.1 - 5.6e-09 35.9 0.1 1.1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS32940.1 - 0.00051 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MOZ_SAS PF01853.18 CDS32941.1 - 1.4e-69 233.4 0.2 1.9e-69 232.9 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDS32941.1 - 1.6e-15 56.4 0.3 3.5e-15 55.4 0.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain zf-C2HC PF01530.18 CDS32941.1 - 1.3e-09 38.1 2.7 1.3e-09 38.1 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, C2HC type Acetyltransf_7 PF13508.7 CDS32941.1 - 0.00048 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDS32941.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDS32941.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MMS1_N PF10433.9 CDS32942.1 - 2.3e-170 567.4 0.0 3.7e-170 566.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDS32942.1 - 3.7e-85 286.1 0.0 7e-84 281.9 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region zf-H2C2_2 PF13465.6 CDS32944.1 - 7.7e-25 86.2 31.4 3.7e-08 33.4 0.6 5.9 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS32944.1 - 3.4e-18 65.0 44.5 2.8e-05 24.3 0.4 6.1 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS32944.1 - 2.2e-13 49.8 41.4 0.01 16.6 0.1 6.9 7 0 0 7 7 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS32944.1 - 1.8e-08 34.4 12.9 0.02 15.2 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS32944.1 - 2.2e-08 34.2 23.0 0.1 13.0 1.0 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDS32944.1 - 3.1e-06 27.0 30.9 0.026 14.5 2.3 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CDS32944.1 - 0.00026 21.0 7.9 0.78 9.9 1.6 4.0 3 2 0 3 3 3 2 Zinc ribbon domain BolA PF01722.18 CDS32944.1 - 0.018 15.3 5.0 3.4 8.0 0.2 3.4 1 1 0 2 2 2 0 BolA-like protein zf-C2HE PF16278.5 CDS32944.1 - 0.023 15.1 32.4 0.8 10.2 2.5 5.8 3 1 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger Scramblase PF03803.15 CDS32944.1 - 0.069 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Scramblase C1_4 PF07975.12 CDS32944.1 - 0.32 11.3 14.0 8.9 6.6 0.0 3.9 2 1 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 CDS32944.1 - 0.43 11.3 12.9 8.2 7.1 1.0 3.9 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 CDS32944.1 - 2.1 8.3 5.8 7.2 6.5 0.0 3.8 3 1 2 5 5 5 0 C2H2 type zinc-finger (1 copy) Globin PF00042.22 CDS32947.1 - 0.023 15.3 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Globin HECT PF00632.25 CDS32948.1 - 4e-85 286.0 0.1 6.9e-85 285.2 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CDS32948.1 - 5.6e-05 22.6 0.2 5.6e-05 22.6 0.2 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif PDZ PF00595.24 CDS32949.1 - 8e-11 42.2 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 CDS32949.1 - 6.1e-09 36.0 3.5 9.6e-09 35.4 3.5 1.3 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 CDS32949.1 - 3.2e-06 26.9 0.0 7.9e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 CDS32949.1 - 0.00013 23.0 0.2 0.00037 21.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) EutA PF06277.11 CDS32949.1 - 0.019 13.9 0.1 0.029 13.2 0.0 1.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA PDZ_2 PF13180.6 CDS32949.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain VATC PF18716.1 CDS32949.1 - 0.4 10.6 5.5 0.7 9.8 2.9 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain PDZ PF00595.24 CDS32950.1 - 1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 CDS32950.1 - 2.2e-08 34.2 0.3 3.8e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 CDS32950.1 - 8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 CDS32950.1 - 0.00016 22.7 0.0 0.00032 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4749) PDZ_2 PF13180.6 CDS32950.1 - 0.09 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain TEP1_N PF05386.11 CDS32950.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 TEP1 N-terminal domain VATC PF18716.1 CDS32950.1 - 1.6 8.6 3.4 0.77 9.7 1.1 1.7 2 0 0 2 2 2 0 Vms1-associating treble clef domain Ig_3 PF13927.6 CDS32952.1 - 2.9e-16 59.8 0.1 6e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS32952.1 - 3.5e-15 55.8 0.0 5.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CDS32952.1 - 2e-10 40.7 0.1 3.7e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CDS32952.1 - 5.7e-10 39.4 0.1 1.1e-09 38.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDS32952.1 - 4e-07 30.2 0.3 1.3e-05 25.3 0.3 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_6 PF18452.1 CDS32952.1 - 0.005 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 CDS32952.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Antimicrobial25 PF16839.5 CDS32952.1 - 0.11 12.7 0.3 0.21 11.7 0.3 1.4 1 0 0 1 1 1 0 Nematode antimicrobial peptide Pyridoxal_deC PF00282.19 CDS32953.1 - 2.9e-10 39.4 0.0 3.8e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDS32953.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Pkinase_Tyr PF07714.17 CDS32955.1 - 0.00024 20.5 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 CDS32957.1 - 0.00054 20.5 1.0 0.037 14.7 0.1 2.7 3 0 0 3 3 3 2 Sel1 repeat Ldh_1_N PF00056.23 CDS32958.1 - 3.6e-43 147.0 1.0 1.3e-42 145.2 0.4 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDS32958.1 - 5.1e-23 81.8 0.0 9.1e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CDS32958.1 - 8.3e-05 22.2 0.7 0.016 14.8 0.1 3.0 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase ThiF PF00899.21 CDS32958.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 CDS32958.1 - 0.091 12.7 0.2 0.33 10.9 0.1 1.9 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 CDS32958.1 - 0.17 11.4 1.5 0.85 9.2 1.5 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GRIN_C PF15235.6 CDS32959.1 - 6.8e-18 65.2 0.5 1.5e-17 64.1 0.5 1.6 1 0 0 1 1 1 1 G protein-regulated inducer of neurite outgrowth C-terminus Phage_integrase PF00589.22 CDS32959.1 - 0.0079 16.0 0.3 0.039 13.7 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family MU117 PF15474.6 CDS32959.1 - 0.021 15.6 0.6 0.15 12.8 0.1 2.3 1 1 1 2 2 2 0 Meiotically up-regulated gene family SET PF00856.28 CDS32960.1 - 1.2e-09 38.7 0.0 3.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 CDS32960.1 - 2.3e-06 28.3 0.1 5.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Mog1 PF04603.12 CDS32961.1 - 3.3e-40 137.6 0.4 4.1e-40 137.4 0.4 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HAT_KAT11 PF08214.11 CDS32962.1 - 1.2e-48 166.2 0.5 1.2e-48 166.2 0.5 2.2 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 CDS32962.1 - 1.3e-15 57.2 0.1 4.5e-15 55.5 0.1 2.0 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 CDS32962.1 - 1.6e-15 57.3 40.8 7.6e-11 42.3 16.8 5.3 5 0 0 5 5 5 2 TAZ zinc finger DUF902 PF06001.13 CDS32962.1 - 1.9e-13 50.6 1.6 4.8e-13 49.4 1.6 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF902) KIX PF02172.16 CDS32962.1 - 6.6e-05 23.1 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 KIX domain UPF0242 PF06785.11 CDS32963.1 - 0.0082 16.3 5.3 0.0082 16.3 5.3 6.1 4 1 2 6 6 6 1 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 CDS32963.1 - 0.016 15.0 2.0 0.016 15.0 2.0 5.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor WBS28 PF15164.6 CDS32963.1 - 0.024 13.9 2.1 0.05 12.9 2.1 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue COR PF16095.5 CDS32963.1 - 0.041 13.7 0.2 0.35 10.7 0.0 2.7 2 0 0 2 2 2 0 C-terminal of Roc, COR, domain DUF3502 PF12010.8 CDS32963.1 - 0.081 13.6 0.5 1.2 9.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) MHB PF16525.5 CDS32963.1 - 0.13 12.5 0.5 0.56 10.5 0.5 2.1 1 0 0 1 1 1 0 Haemophore, haem-binding PX PF00787.24 CDS32963.1 - 0.17 11.9 1.1 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 PX domain DUF2250 PF10007.9 CDS32963.1 - 0.66 10.1 5.1 0.79 9.9 0.4 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Golgin_A5 PF09787.9 CDS32963.1 - 1.2 8.5 64.9 0.22 10.9 3.0 5.1 3 1 0 4 4 4 0 Golgin subfamily A member 5 ANAPC5 PF12862.7 CDS32963.1 - 2.2 8.4 5.1 45 4.2 0.2 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 Med4 PF10018.9 CDS32964.1 - 3e-21 76.0 1.5 3.1e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Arm_vescicular PF18770.1 CDS32964.1 - 0.018 15.0 0.3 0.043 13.8 0.3 1.6 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor OPA3 PF07047.12 CDS32965.1 - 1.9e-38 131.0 0.0 2.5e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) PspB PF06667.12 CDS32965.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B 2-oxoacid_dh PF00198.23 CDS32966.1 - 1.5e-78 263.5 0.0 1.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDS32966.1 - 2.6e-17 62.4 1.1 5.4e-17 61.4 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDS32966.1 - 0.00025 20.8 0.0 0.00091 19.0 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 CDS32966.1 - 0.0019 18.1 3.0 0.0031 17.4 1.2 2.0 1 1 1 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.6 CDS32966.1 - 0.0036 17.2 0.5 0.082 12.9 0.3 2.5 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CDS32966.1 - 0.012 14.8 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion EGF PF00008.27 CDS32967.1 - 3.4e-13 49.6 29.6 1.9e-06 28.0 7.2 3.8 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 CDS32967.1 - 4.9e-09 36.5 35.8 8.2e-06 26.3 7.4 4.3 3 0 0 3 3 3 3 Human growth factor-like EGF EGF_2 PF07974.13 CDS32967.1 - 1.1e-08 35.3 45.7 0.00033 21.0 6.0 4.2 4 0 0 4 4 4 3 EGF-like domain Laminin_EGF PF00053.24 CDS32967.1 - 0.0067 16.5 34.1 0.043 13.9 6.3 4.4 2 1 2 4 4 4 3 Laminin EGF domain DSL PF01414.19 CDS32967.1 - 0.49 10.7 36.6 0.64 10.3 0.3 4.4 3 1 1 4 4 4 0 Delta serrate ligand EGF PF00008.27 CDS32968.1 - 4.6e-17 62.0 59.5 2.3e-06 27.8 0.2 7.0 6 1 0 6 6 6 5 EGF-like domain hEGF PF12661.7 CDS32968.1 - 5.1e-10 39.6 75.3 0.0026 18.3 3.4 8.3 8 0 0 8 8 8 5 Human growth factor-like EGF EGF_2 PF07974.13 CDS32968.1 - 8.7e-07 29.2 81.0 0.0004 20.7 10.3 6.8 6 1 0 6 6 6 4 EGF-like domain DSL PF01414.19 CDS32968.1 - 0.00017 21.8 1.3 0.00017 21.8 1.3 4.7 4 0 0 4 4 4 1 Delta serrate ligand RCR PF12273.8 CDS32968.1 - 0.0086 16.7 0.4 0.018 15.7 0.0 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red EGF_3 PF12947.7 CDS32968.1 - 5.3 7.3 48.8 0.22 11.7 5.1 6.0 4 1 1 5 5 5 0 EGF domain Plasmod_Pvs28 PF06247.11 CDS32968.1 - 7.9 6.9 40.2 0.058 13.7 1.6 4.9 4 1 1 5 5 5 0 Pvs28 EGF domain TIP49 PF06068.13 CDS32969.1 - 1.5e-169 563.8 0.6 1.8e-169 563.5 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDS32969.1 - 2e-18 66.2 0.2 7e-18 64.5 0.2 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDS32969.1 - 2.5e-10 40.9 0.6 7.3e-06 26.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDS32969.1 - 4.2e-09 36.4 0.2 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDS32969.1 - 0.00093 19.5 0.0 0.054 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDS32969.1 - 0.0018 17.7 0.1 0.88 8.9 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CDS32969.1 - 0.0086 16.5 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CDS32969.1 - 0.01 15.9 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDS32969.1 - 0.012 15.3 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CDS32969.1 - 0.015 15.9 0.0 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDS32969.1 - 0.015 15.3 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 CDS32969.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DnaB_C PF03796.15 CDS32969.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 CDS32969.1 - 0.028 13.7 0.0 0.094 12.0 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 CDS32969.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDS32969.1 - 0.12 12.5 0.0 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CDS32969.1 - 2.4 8.5 6.5 14 6.0 2.3 3.1 2 1 0 2 2 2 0 AAA domain Oxysterol_BP PF01237.18 CDS32970.2 - 9.4e-140 465.7 0.0 1.5e-139 465.0 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDS32970.2 - 1.2e-07 32.1 2.4 9.9e-07 29.2 2.4 2.3 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 CDS32970.2 - 6.3e-07 29.6 0.3 1.4e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDS32970.2 - 0.0015 19.0 5.7 0.23 11.9 1.8 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain XhlA PF10779.9 CDS32970.2 - 0.012 15.7 2.2 0.32 11.2 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA SRP68 PF16969.5 CDS32970.2 - 0.072 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 BLOC1_2 PF10046.9 CDS32970.2 - 0.25 11.6 1.0 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MbeD_MobD PF04899.12 CDS32970.2 - 0.29 11.3 4.0 0.2 11.8 1.7 1.9 2 0 0 2 2 2 0 MbeD/MobD like Prefoldin_2 PF01920.20 CDS32970.2 - 0.38 10.7 2.2 14 5.7 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 CDS32970.2 - 0.63 9.9 2.2 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.15 CDS32971.1 - 2e-27 95.2 0.2 3.9e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CDS32971.1 - 3e-12 46.4 0.5 3.2e-11 43.2 0.5 2.4 1 1 0 1 1 1 1 Leucine zipper with capping helix domain FUR PF01475.19 CDS32971.1 - 0.0041 17.2 0.0 0.0094 16.1 0.0 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family Penicillinase_R PF03965.16 CDS32971.1 - 0.02 15.2 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Penicillinase repressor Ribosomal_L31e PF01198.19 CDS32972.1 - 3.1e-45 152.3 0.7 4.3e-45 151.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Mitofilin PF09731.9 CDS32973.1 - 7.1e-53 180.4 20.9 1.8e-42 146.0 16.6 2.4 2 1 0 2 2 2 2 Mitochondrial inner membrane protein Hormone_1 PF00103.20 CDS32973.1 - 0.051 13.3 4.4 0.045 13.5 2.4 2.0 2 0 0 2 2 2 0 Somatotropin hormone family Mt_ATP-synt_B PF05405.14 CDS32973.1 - 0.22 11.1 16.7 0.017 14.8 9.8 2.4 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5446 PF17522.2 CDS32973.1 - 6.9 6.9 6.0 7.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5446) 7tm_1 PF00001.21 CDS32975.1 - 1.6e-42 145.7 7.4 5.6e-42 143.9 3.9 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS32975.1 - 2.6e-08 33.6 19.0 2.9e-06 26.9 15.2 2.4 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx TMEM100 PF16311.5 CDS32975.1 - 0.048 13.2 1.4 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2207 PF09972.9 CDS32975.1 - 7.2 5.2 10.5 10 4.8 0.9 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) C_Hendra PF16821.5 CDS32976.1 - 0.043 13.7 0.6 0.074 12.9 0.6 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses DUF5600 PF18150.1 CDS32978.1 - 8.8e-42 142.0 0.9 1.8e-41 141.1 0.4 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CDS32978.1 - 6.1e-16 58.9 0.0 2.4e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CDS32978.1 - 5.6e-15 54.9 1.5 5.6e-15 54.9 1.5 2.0 2 0 0 2 2 2 1 N-terminal EH-domain containing protein EF-hand_4 PF12763.7 CDS32978.1 - 7.1e-14 51.6 0.0 2.7e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 CDS32978.1 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.6 CDS32978.1 - 0.00025 20.8 0.4 0.51 10.2 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS32978.1 - 0.00032 20.0 0.0 0.0027 17.1 0.0 2.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDS32978.1 - 0.01 15.7 0.3 0.11 12.5 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Roc PF08477.13 CDS32978.1 - 0.029 14.6 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Retrotran_gag_2 PF14223.6 CDS32978.1 - 0.038 13.7 0.0 4.8 6.8 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type EF-hand_7 PF13499.6 CDS32978.1 - 0.041 14.3 0.3 0.29 11.6 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair Thioredoxin PF00085.20 CDS32979.1 - 6.1e-17 61.5 0.1 8.6e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDS32979.1 - 0.001 19.5 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDS32979.1 - 0.031 13.6 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Exo_endo_phos PF03372.23 CDS32980.1 - 2.6e-05 23.8 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 CDS32981.1 - 0.0003 20.5 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IF-2B PF01008.17 CDS32982.1 - 1.4e-38 132.7 0.0 2.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PRORP PF16953.5 CDS32986.1 - 1.6e-36 126.1 0.0 2.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P DUF3504 PF12012.8 CDS32987.1 - 2.3e-11 43.9 0.0 5.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) zf-C2HE PF16278.5 CDS32987.1 - 0.54 10.8 0.0 0.54 10.8 0.0 2.8 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger MCM PF00493.23 CDS32988.1 - 2.9e-91 304.5 0.0 4.4e-91 303.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS32988.1 - 4.6e-32 110.5 0.1 7.6e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS32988.1 - 9.4e-23 80.5 3.1 1.9e-22 79.4 3.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDS32988.1 - 1.7e-06 27.5 0.0 4.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDS32988.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDS32988.1 - 0.096 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDS32988.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PfkB PF00294.24 CDS32989.1 - 6.9e-47 160.2 0.0 4.2e-46 157.6 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DEAD PF00270.29 CDS32990.1 - 4.4e-47 160.1 0.0 9.6e-47 159.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS32990.1 - 5.9e-29 100.6 0.2 2.4e-27 95.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GTA_TIM PF13547.6 CDS32990.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 GTA TIM-barrel-like domain KH_1 PF00013.29 CDS32991.1 - 6e-15 54.8 0.1 8.6e-08 31.9 0.0 2.8 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 CDS32991.1 - 0.008 16.6 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 Agenet domain KH_9 PF17904.1 CDS32991.1 - 0.097 13.1 0.0 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 FMRP KH0 domain Sugar_tr PF00083.24 CDS32992.1 - 3.2e-97 326.2 20.6 3.6e-97 326.1 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS32992.1 - 1.1e-16 60.7 17.3 1.1e-16 60.7 17.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3165 PF11364.8 CDS32992.1 - 6.8 7.1 12.6 1.7 9.1 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3165) Sugar_tr PF00083.24 CDS32993.1 - 5.4e-97 325.5 19.7 6.4e-97 325.2 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS32993.1 - 1.4e-22 80.1 41.4 7.8e-22 77.7 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF410 PF04190.13 CDS32995.1 - 1.1e-53 182.7 0.0 1.5e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SUFU PF05076.13 CDS32996.1 - 1.9e-40 138.7 0.0 1.3e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 Suppressor of fused protein (SUFU) SUFU_C PF12470.8 CDS32996.1 - 1.2e-39 136.5 0.0 1.6e-37 129.6 0.0 2.5 1 1 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain PHD PF00628.29 CDS32997.1 - 0.0016 18.3 9.4 0.0016 18.3 9.4 2.8 3 1 1 4 4 4 1 PHD-finger zf-MYND PF01753.18 CDS32997.1 - 0.0025 17.8 21.3 0.0025 17.8 21.3 3.7 4 0 0 4 4 4 1 MYND finger Bromodomain PF00439.25 CDS32997.1 - 0.01 15.9 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 0 Bromodomain COG2 PF06148.11 CDS32998.1 - 7.2e-31 107.0 7.6 8.1e-31 106.9 1.8 3.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CDS32998.1 - 1.5e-27 96.4 0.3 1.5e-27 96.4 0.3 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3510) SKA1 PF07160.12 CDS32998.1 - 0.023 14.6 5.3 0.22 11.3 0.8 2.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 EcoR124_C PF12008.8 CDS32998.1 - 0.024 14.3 2.1 0.046 13.4 0.9 1.9 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Vps51 PF08700.11 CDS32998.1 - 0.072 13.2 1.9 0.25 11.4 0.2 3.0 3 0 0 3 3 3 0 Vps51/Vps67 CLZ PF16526.5 CDS32998.1 - 0.28 11.5 3.6 10 6.6 0.0 4.6 5 1 1 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 CDS32998.1 - 0.39 10.8 7.9 22 5.1 0.2 4.7 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 CDS32998.1 - 1.8 9.0 11.5 1.9 8.8 0.3 3.6 3 1 0 4 4 4 0 YlqD protein Fez1 PF06818.15 CDS32998.1 - 5.3 7.5 6.8 1.8 8.9 0.9 2.5 2 1 0 2 2 2 0 Fez1 Apolipoprotein PF01442.18 CDS32998.1 - 7 6.5 10.2 4.2 7.2 0.1 4.0 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain TMF_TATA_bd PF12325.8 CDS32999.1 - 0.00074 19.7 1.1 0.36 11.1 0.0 2.4 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CDS32999.1 - 0.0035 16.7 2.3 0.38 10.1 0.3 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 CDS32999.1 - 0.0059 17.0 9.0 0.41 11.1 1.1 3.2 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein ASD2 PF08687.11 CDS32999.1 - 0.0075 15.9 1.3 0.014 15.0 1.4 1.5 1 1 0 1 1 1 1 Apx/Shroom domain ASD2 H-kinase_dim PF02895.14 CDS32999.1 - 0.022 15.1 1.2 6.3 7.3 0.8 3.2 1 1 2 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Synaptobrevin PF00957.21 CDS32999.1 - 0.023 14.5 0.5 0.023 14.5 0.5 2.7 3 1 0 3 3 3 0 Synaptobrevin BLOC1_2 PF10046.9 CDS32999.1 - 0.04 14.2 7.0 2.5 8.4 0.1 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 CDS32999.1 - 0.16 12.1 1.8 7.6 6.6 0.1 2.6 2 1 0 2 2 2 0 DivIVA protein Gp-FAR-1 PF05823.12 CDS32999.1 - 0.18 12.2 3.3 2.7 8.3 0.5 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4201 PF13870.6 CDS32999.1 - 0.47 10.2 6.3 0.81 9.4 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.6 CDS32999.1 - 0.94 9.6 5.2 11 6.2 0.0 3.8 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DHR10 PF18595.1 CDS32999.1 - 0.95 9.5 4.0 7.2 6.7 0.2 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 CDS32999.1 - 1.5 9.2 6.5 11 6.6 0.9 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 CDS32999.1 - 2.7 7.9 8.9 1.8 8.5 0.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit FliD_N PF02465.18 CDS32999.1 - 4.6 8.0 6.7 34 5.2 0.2 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus LPP PF04728.13 CDS32999.1 - 4.9 7.6 9.6 2 8.9 1.2 3.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper WWE PF02825.20 CDS33000.1 - 1.9e-17 63.6 1.0 2.6e-17 63.2 1.0 1.2 1 0 0 1 1 1 1 WWE domain zf-C3HC4_3 PF13920.6 CDS33000.1 - 4.9e-09 35.9 6.1 9.2e-09 35.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS33000.1 - 2.3e-08 34.2 9.4 5e-08 33.1 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDS33000.1 - 9.9e-08 31.7 9.1 1.9e-07 30.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS33000.1 - 1.1e-07 31.7 9.3 1.2e-07 31.6 7.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS33000.1 - 4.6e-07 29.6 10.3 1e-06 28.5 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDS33000.1 - 7.8e-07 29.1 10.7 2.2e-06 27.7 10.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDS33000.1 - 1.1e-06 28.5 7.0 1.9e-06 27.7 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS33000.1 - 4.3e-05 23.3 15.4 0.00012 21.9 11.3 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CDS33000.1 - 0.034 14.3 2.9 0.062 13.4 2.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CDS33000.1 - 0.062 13.1 4.5 0.17 11.7 4.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CDS33000.1 - 0.084 13.2 8.7 0.36 11.1 8.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 CDS33000.1 - 1.1 9.2 6.1 3.8 7.4 6.2 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 CDS33000.1 - 2.9 7.8 5.3 29 4.6 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Auto_anti-p27 PF06677.12 CDS33000.1 - 3.2 8.0 6.0 25 5.1 3.8 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) EIF4E-T PF10477.9 CDS33001.1 - 0.0056 15.6 4.4 0.0056 15.6 4.4 3.2 2 1 1 3 3 3 2 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Calreticulin PF00262.18 CDS33002.1 - 5.2e-149 496.1 5.5 7.6e-149 495.5 5.5 1.2 1 0 0 1 1 1 1 Calreticulin family USP7_C2 PF14533.6 CDS33002.1 - 1.3e-47 162.2 0.0 2.2e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 CDS33002.1 - 3.4e-05 23.3 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 FAM176 PF14851.6 CDS33002.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 FAM176 family Syndecan PF01034.20 CDS33002.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Orthoreo_P10 PF07204.11 CDS33002.1 - 0.2 11.7 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Pkinase PF00069.25 CDS33003.1 - 3e-37 128.4 0.0 3.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33003.1 - 4.1e-18 65.6 0.0 5.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS33003.1 - 0.00011 21.1 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDS33003.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDS33003.1 - 0.023 14.6 0.4 0.062 13.2 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PepSY_like PF11396.8 CDS33003.1 - 0.026 15.1 0.1 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like RIO1 PF01163.22 CDS33003.1 - 0.052 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RVT_3 PF13456.6 CDS33003.1 - 0.069 13.0 0.0 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Pox_ser-thr_kin PF05445.11 CDS33003.1 - 0.1 11.6 1.0 0.5 9.3 0.1 2.3 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Chorion_3 PF05387.11 CDS33004.1 - 0.78 9.3 5.5 0.86 9.2 5.5 1.1 1 0 0 1 1 1 0 Chorion family 3 SelK_SelG PF10961.8 CDS33004.1 - 9 7.0 14.0 13 6.4 13.3 1.7 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Ank_2 PF12796.7 CDS33005.1 - 4.2e-20 72.1 5.5 1.9e-09 38.0 0.2 3.6 1 1 4 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS33005.1 - 3.8e-12 46.5 1.7 8.5e-06 26.2 0.1 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS33005.1 - 3.8e-11 43.0 3.5 0.0036 17.6 0.1 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33005.1 - 1.9e-07 30.8 4.4 2.1 9.2 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CDS33005.1 - 0.0028 18.0 4.9 3.6 8.2 0.1 4.0 4 1 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 CDS33006.1 - 3.8e-76 256.0 0.0 5.3e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.10 CDS33006.1 - 1.1e-39 135.4 0.0 2.7e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase_Tyr PF07714.17 CDS33006.1 - 1.7e-34 119.3 0.0 2.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4440 PF14534.6 CDS33006.1 - 1.1e-09 38.7 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 CDS33006.1 - 2.1e-06 28.0 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.23 CDS33006.1 - 0.003 17.5 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS33006.1 - 0.0032 16.3 0.0 0.0078 15.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CDS33006.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDS33006.1 - 0.012 15.0 0.1 0.029 13.7 0.0 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tox-REase-7 PF15649.6 CDS33006.1 - 0.077 13.3 0.1 3.4 8.0 0.0 2.8 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 YrbL-PhoP_reg PF10707.9 CDS33006.1 - 0.081 12.4 0.3 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CH PF00307.31 CDS33008.1 - 1.2e-09 38.3 0.0 2.1e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CDS33008.1 - 2.3e-07 30.3 2.2 4.6e-07 29.4 2.2 1.5 1 0 0 1 1 1 1 Calponin family repeat CH PF00307.31 CDS33009.1 - 4e-09 36.6 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 CDS33009.1 - 3.6e-08 32.9 1.9 6.6e-08 32.0 1.9 1.5 1 0 0 1 1 1 1 Calponin family repeat AAA_6 PF12774.7 CDS33010.2 - 4.4e-159 528.7 0.1 2.8e-158 526.1 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS33010.2 - 9.5e-144 479.4 7.8 9.5e-144 479.4 7.8 4.3 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CDS33010.2 - 8.1e-113 376.7 0.1 2.7e-112 375.0 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDS33010.2 - 4.5e-103 344.1 0.0 1.3e-102 342.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS33010.2 - 2.3e-88 295.0 0.3 1.1e-87 292.8 0.3 2.4 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS33010.2 - 1.3e-76 256.2 0.0 2.6e-74 248.7 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS33010.2 - 1e-59 201.0 0.1 4.1e-59 199.0 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS33010.2 - 9e-46 156.5 5.1 1.8e-45 155.5 5.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS33010.2 - 3.1e-44 149.9 0.0 6.7e-43 145.6 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CDS33010.2 - 2.3e-33 115.0 0.0 9.7e-33 113.0 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CDS33010.2 - 1.3e-23 83.5 0.0 9.3e-08 32.2 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS33010.2 - 6.1e-19 68.1 0.5 1.8e-17 63.3 0.1 3.1 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CDS33010.2 - 3.9e-06 27.3 0.0 0.058 13.8 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDS33010.2 - 7.3e-05 23.1 0.0 3.6 8.0 0.0 4.8 5 0 0 5 5 4 1 RNA helicase AAA_22 PF13401.6 CDS33010.2 - 0.0013 19.0 2.5 2.9 8.2 0.0 5.5 6 0 0 6 6 6 1 AAA domain AAA_16 PF13191.6 CDS33010.2 - 0.0014 19.1 1.1 2.9 8.3 0.0 4.4 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 CDS33010.2 - 0.0028 16.7 0.0 0.012 14.7 0.0 2.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 CDS33010.2 - 0.0054 16.4 0.0 0.095 12.4 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 CDS33010.2 - 0.041 14.0 0.0 7.5 6.7 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 CDS33010.2 - 0.054 14.0 3.3 1.9 9.1 0.0 4.7 6 0 0 6 6 4 0 AAA domain Mg_chelatase PF01078.21 CDS33010.2 - 0.091 12.1 0.0 9.8 5.5 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CDS33010.2 - 0.094 12.4 0.0 4.7 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF1664 PF07889.12 CDS33010.2 - 6.3 6.8 6.1 4.2 7.4 0.7 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PI3_PI4_kinase PF00454.27 CDS33011.1 - 1.5e-30 106.9 0.0 3.3e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 CDS33011.1 - 8.2e-29 100.7 0.0 2.6e-28 99.1 0.0 1.8 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.23 CDS33011.1 - 4.4e-06 26.1 0.6 1.4e-05 24.5 0.3 1.9 1 1 1 2 2 2 1 FAT domain FATC PF02260.20 CDS33011.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 FATC domain Pkinase PF00069.25 CDS33012.1 - 7.6e-69 232.0 0.0 9.3e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33012.1 - 1.3e-33 116.4 0.0 1.8e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS33012.1 - 3e-07 30.0 0.1 2.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDS33012.1 - 1.2e-06 27.7 0.1 2.1e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDS33012.1 - 1.6e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS33012.1 - 0.0045 16.9 0.1 0.045 13.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDS33012.1 - 0.0073 15.9 0.2 2.8 7.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDS33012.1 - 0.085 11.6 0.3 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase MOLO1 PF17175.4 CDS33013.1 - 1.3e-26 93.1 0.0 1.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 CDS33013.1 - 1.1e-05 25.6 0.1 5.7e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 TPM domain ABC2_membrane_3 PF12698.7 CDS33015.2 - 0.087 11.9 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GWT1 PF06423.12 CDS33016.2 - 2.1e-10 40.9 0.2 2.1e-10 40.9 0.2 1.6 2 0 0 2 2 2 1 GWT1 Pro_isomerase PF00160.21 CDS33017.1 - 1.5e-51 174.8 0.0 2.8e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDS33017.1 - 4.3e-15 55.8 0.9 0.0055 17.5 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS33017.1 - 0.0013 19.0 0.0 7.3 7.0 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_6 PF12774.7 CDS33018.2 - 3.6e-163 542.2 0.0 9.9e-163 540.7 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS33018.2 - 1.2e-124 416.5 2.6 1.2e-124 416.5 2.6 3.1 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CDS33018.2 - 2.6e-100 335.6 0.1 1.2e-99 333.4 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CDS33018.2 - 1.2e-98 329.5 0.0 4.4e-98 327.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS33018.2 - 3.1e-92 307.7 1.8 3.1e-92 307.7 1.8 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CDS33018.2 - 4.5e-78 260.9 0.1 3.6e-71 238.4 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS33018.2 - 6.1e-54 182.2 0.2 9.3e-52 175.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDS33018.2 - 7.5e-47 158.3 0.0 1.7e-43 147.5 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CDS33018.2 - 1.2e-33 116.7 11.5 2.5e-33 115.5 11.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CDS33018.2 - 1.4e-21 77.0 0.0 9.3e-08 32.2 0.0 6.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS33018.2 - 2.7e-19 69.2 0.0 1.3e-18 67.0 0.0 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDS33018.2 - 4.7e-18 65.5 0.0 3.1e-17 62.9 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CDS33018.2 - 4.3e-11 43.2 2.6 0.0058 16.9 0.0 5.5 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 CDS33018.2 - 1.1e-10 42.0 2.3 0.024 15.1 0.0 6.0 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDS33018.2 - 1.8e-10 41.5 3.4 0.074 13.6 0.0 6.3 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.6 CDS33018.2 - 2.3e-09 37.8 5.7 0.01 16.2 0.0 5.8 6 0 0 6 6 4 1 AAA ATPase domain TsaE PF02367.17 CDS33018.2 - 5.8e-08 32.8 2.4 0.058 13.4 0.0 4.4 4 0 0 4 4 4 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CDS33018.2 - 3.6e-06 26.2 0.1 0.26 10.3 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein RNA_helicase PF00910.22 CDS33018.2 - 1e-05 25.9 0.0 1.8 9.0 0.0 4.2 3 0 0 3 3 3 2 RNA helicase Sigma54_activat PF00158.26 CDS33018.2 - 8.8e-05 22.3 0.8 0.034 13.8 0.0 3.7 4 0 0 4 4 4 1 Sigma-54 interaction domain NB-ARC PF00931.22 CDS33018.2 - 0.0016 17.7 0.5 0.082 12.1 0.0 3.4 3 0 0 3 3 3 1 NB-ARC domain AAA_29 PF13555.6 CDS33018.2 - 0.0023 17.6 0.3 11 5.8 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CDS33018.2 - 0.0025 17.6 0.1 4.8 6.9 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 CDS33018.2 - 0.004 17.3 1.5 1.9 8.7 0.0 4.5 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 CDS33018.2 - 0.0053 16.5 2.1 18 5.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_2 PF07724.14 CDS33018.2 - 0.0076 16.4 0.1 1.8 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 CDS33018.2 - 0.013 16.0 5.5 1.1 9.7 0.0 4.2 4 0 0 4 4 2 0 ABC transporter RuvB_N PF05496.12 CDS33018.2 - 0.031 14.0 0.2 2.3 7.9 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CDS33018.2 - 0.032 14.2 0.5 15 5.6 0.0 3.1 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 CDS33018.2 - 0.037 14.0 0.2 0.99 9.3 0.0 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain DEAD PF00270.29 CDS33018.2 - 0.039 13.7 0.0 5.7 6.7 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CDS33018.2 - 0.056 12.8 1.1 1.9 7.8 0.0 3.1 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Trans_reg_C PF00486.28 CDS33018.2 - 0.084 13.0 0.2 0.74 9.9 0.1 2.8 2 0 0 2 2 1 0 Transcriptional regulatory protein, C terminal Zeta_toxin PF06414.12 CDS33018.2 - 0.092 12.0 0.2 17 4.6 0.0 3.6 3 0 0 3 3 3 0 Zeta toxin DUF853 PF05872.12 CDS33018.2 - 0.095 11.3 0.6 10 4.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Salt_tol_Pase PF09506.10 CDS33018.2 - 0.11 11.2 0.0 0.26 10.0 0.0 1.5 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Roc PF08477.13 CDS33018.2 - 0.16 12.2 0.4 5.5 7.2 0.1 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Trimer_CC PF08954.11 CDS33018.2 - 0.18 11.4 0.8 0.63 9.6 0.8 1.9 1 0 0 1 1 1 0 Trimerisation motif SRP54 PF00448.22 CDS33018.2 - 0.36 10.4 7.1 1.7 8.3 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CDS33018.2 - 0.55 10.5 4.5 3.5 7.8 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 CDS33018.2 - 0.56 9.9 2.1 39 3.9 0.1 3.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CDS33018.2 - 1.7 8.5 4.1 7.5 6.4 0.0 3.4 3 0 0 3 3 3 0 NTPase PriC PF07445.12 CDS33018.2 - 2.2 8.2 9.2 0.088 12.7 0.6 3.0 3 0 0 3 3 2 0 Primosomal replication protein priC Atg14 PF10186.9 CDS33018.2 - 2.9 6.9 10.6 0.28 10.2 3.0 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_25 PF13481.6 CDS33018.2 - 4.2 6.9 8.2 8.1 6.0 0.0 4.3 5 0 0 5 5 4 0 AAA domain DUF641 PF04859.12 CDS33018.2 - 7.7 6.9 9.3 15 5.9 1.2 3.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GPO PF05929.11 CDS33018.2 - 7.8 6.0 8.7 1.1 8.8 1.0 2.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase zf-C2H2 PF00096.26 CDS33019.2 - 5.9e-18 64.3 62.7 0.0006 20.1 1.3 9.7 10 0 0 10 10 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33019.2 - 2.9e-17 61.9 66.5 0.013 16.2 0.5 10.7 11 0 0 11 11 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS33019.2 - 3.2e-10 39.9 54.3 1.1e-05 25.6 1.7 9.3 10 1 0 10 10 9 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS33019.2 - 4.4e-08 33.2 38.1 0.035 14.4 0.3 7.7 9 0 0 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS33019.2 - 1.5e-07 31.7 35.9 0.59 10.5 1.2 7.4 1 1 6 7 7 7 4 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CDS33019.2 - 0.00013 21.9 45.1 0.049 13.6 0.2 8.4 9 0 0 9 9 8 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDS33019.2 - 0.00065 20.4 27.1 0.078 13.7 6.6 4.6 1 1 4 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CDS33019.2 - 0.0012 19.1 4.4 0.017 15.5 0.4 6.7 8 0 0 8 8 7 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDS33019.2 - 0.0048 17.2 4.7 0.0048 17.2 4.7 5.7 4 3 3 7 7 6 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CDS33019.2 - 0.015 15.0 2.8 0.015 15.0 2.8 8.6 9 1 0 9 9 7 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 CDS33019.2 - 0.054 14.1 0.2 0.054 14.1 0.2 5.1 4 1 2 6 6 5 0 FOXP coiled-coil domain Elf1 PF05129.13 CDS33019.2 - 0.057 13.5 33.3 0.2 11.7 3.5 5.6 3 2 1 4 4 4 0 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 CDS33019.2 - 0.13 12.1 9.0 2.7 7.9 0.0 5.4 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 CDS33019.2 - 0.16 12.7 0.2 0.16 12.7 0.2 5.1 2 1 3 5 5 5 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 CDS33019.2 - 0.29 11.6 6.2 24 5.5 0.2 4.7 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-RRPl_C4 PF17026.5 CDS33019.2 - 0.48 10.5 17.9 3.3 7.8 5.5 3.9 3 1 1 4 4 4 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF629 PF04780.12 CDS33019.2 - 1.4 7.4 23.1 2 6.9 1.4 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF629) ARS2 PF04959.13 CDS33019.2 - 3.3 8.0 7.7 2.9 8.2 2.4 2.4 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Cytochrom_B561 PF03188.16 CDS33020.2 - 6.2e-14 52.3 0.2 1.1e-13 51.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PhaG_MnhG_YufB PF03334.14 CDS33020.2 - 0.0009 19.4 0.4 0.89 9.8 0.2 2.3 1 1 0 2 2 2 2 Na+/H+ antiporter subunit MnhB PF04039.13 CDS33020.2 - 0.022 15.0 0.3 0.082 13.2 0.1 1.9 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Ni_hydr_CYTB PF01292.20 CDS33020.2 - 0.19 11.3 5.5 0.68 9.5 5.5 1.9 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 SdpI PF13630.6 CDS33020.2 - 0.33 11.1 5.9 1.2 9.3 0.2 2.6 2 1 1 3 3 3 0 SdpI/YhfL protein family TctB PF07331.11 CDS33020.2 - 0.84 9.9 4.9 0.47 10.7 0.3 2.1 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF308 PF03729.13 CDS33020.2 - 2.4 8.5 12.1 0.54 10.6 2.2 3.0 2 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF3040 PF11239.8 CDS33020.2 - 7.3 6.9 8.3 9.2 6.6 0.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) GWT1 PF06423.12 CDS33021.1 - 0.00031 20.9 3.4 0.00038 20.6 0.0 2.7 2 1 0 2 2 2 1 GWT1 DUF812 PF05667.11 CDS33022.1 - 0.00061 18.8 35.1 0.00061 18.8 35.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF812) AAA_13 PF13166.6 CDS33022.1 - 0.0018 17.0 30.5 0.0018 17.0 30.5 2.3 1 1 1 2 2 2 1 AAA domain zf-C2H2_9 PF16293.5 CDS33022.1 - 0.044 13.6 2.9 0.23 11.4 0.3 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Filament PF00038.21 CDS33022.1 - 0.4 10.2 47.3 0.035 13.7 11.2 3.7 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 CDS33022.1 - 0.5 9.2 54.7 0.13 11.1 21.1 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF2968 PF11180.8 CDS33022.1 - 0.91 9.1 39.8 0.046 13.3 13.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Vac_Fusion PF02346.16 CDS33022.1 - 0.99 9.1 5.8 0.57 9.8 0.1 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 ATG16 PF08614.11 CDS33022.1 - 2.5 8.3 47.8 33 4.6 29.5 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 CDS33022.1 - 7.3 6.9 16.5 0.76 10.1 2.3 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Oxysterol_BP PF01237.18 CDS33023.2 - 8.8e-74 248.6 0.0 1.9e-72 244.2 0.0 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CDS33023.2 - 2e-13 50.8 0.1 5e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDS33023.2 - 1.3e-10 41.4 0.5 2.7e-10 40.4 0.5 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDS33023.2 - 2.6e-07 31.0 2.7 6e-06 26.6 2.7 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CDS33023.2 - 0.0041 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 CDS33023.2 - 0.0073 16.6 0.1 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 CDS33023.2 - 0.034 14.2 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 PH domain Sec3-PIP2_bind PF15277.6 CDS33023.2 - 0.082 13.0 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Na_sulph_symp PF00939.19 CDS33025.1 - 3.1e-69 234.2 20.8 3.8e-69 233.9 20.8 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CDS33025.1 - 2.6e-32 112.2 42.9 6.6e-20 71.5 4.1 3.1 2 1 1 3 3 3 3 Citrate transporter GntP_permease PF02447.16 CDS33025.1 - 0.031 13.0 24.4 0.008 14.9 8.7 3.3 2 1 1 3 3 3 0 GntP family permease WD40 PF00400.32 CDS33026.1 - 1e-12 48.3 3.7 0.00066 20.4 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat HIT PF01230.23 CDS33027.1 - 5.3e-27 94.4 0.3 1.1e-26 93.4 0.3 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDS33027.1 - 5.1e-21 75.3 3.3 1.9e-20 73.5 3.3 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CDS33028.1 - 2.5e-31 108.3 0.1 3.3e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDS33028.1 - 1.3e-25 90.1 0.1 1.6e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding I-set PF07679.16 CDS33029.1 - 1e-36 124.9 0.0 5.4e-12 45.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS33029.1 - 1.2e-29 102.7 0.3 4.5e-09 36.8 0.0 4.7 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CDS33029.1 - 3.7e-19 68.8 0.5 6.7e-07 29.6 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CDS33029.1 - 1.7e-14 53.7 0.0 8.6e-09 35.5 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain C1-set PF07654.15 CDS33029.1 - 5.8e-05 23.4 0.0 1 9.8 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin C1-set domain C2-set_2 PF08205.12 CDS33029.1 - 0.001 19.1 0.8 0.78 9.8 0.0 4.2 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS33029.1 - 0.0029 17.1 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CDS33029.1 - 0.078 13.2 13.9 0.092 12.9 0.0 4.9 4 2 0 4 4 4 0 Immunoglobulin V-set domain ETC_C1_NDUFA4 PF04800.12 CDS33031.1 - 2.8e-37 126.8 0.7 4e-37 126.4 0.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region YL1 PF05764.13 CDS33032.1 - 3.3e-41 142.0 32.8 4.3e-41 141.6 32.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 CDS33032.1 - 7.1e-12 44.9 0.1 1.2e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Cullin PF00888.22 CDS33033.2 - 1.9e-23 83.0 0.0 3.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Cullin family FERM_M PF00373.18 CDS33033.2 - 8.5e-22 77.8 0.0 2.4e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 CDS33033.2 - 9.1e-22 77.3 0.0 2.7e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 FERM C-terminal PH-like domain ANAPC2 PF08672.11 CDS33033.2 - 5.3e-15 55.7 0.1 1.5e-14 54.2 0.1 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FERM_N PF09379.10 CDS33033.2 - 9.7e-10 38.3 0.0 2.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain ERM PF00769.19 CDS33033.2 - 1.3e-06 28.5 0.1 1.3e-06 28.5 0.1 3.1 2 1 0 2 2 2 1 Ezrin/radixin/moesin family HTH_IclR PF09339.10 CDS33033.2 - 0.0034 17.2 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 CDS33033.2 - 0.012 15.4 0.1 0.043 13.7 0.0 2.0 2 0 0 2 2 2 0 MarR family HEAT PF02985.22 CDS33034.2 - 2.2e-40 133.2 53.3 0.00087 19.3 0.0 17.2 17 1 0 17 17 17 13 HEAT repeat HEAT_2 PF13646.6 CDS33034.2 - 4.7e-35 119.9 26.6 2.7e-09 37.3 0.0 9.7 3 2 7 10 10 10 9 HEAT repeats Cnd1 PF12717.7 CDS33034.2 - 1.1e-11 45.1 14.7 0.091 12.8 0.3 6.7 2 1 5 7 7 7 6 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CDS33034.2 - 2.6e-10 40.8 1.9 1.2 9.8 0.0 7.9 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CDS33034.2 - 8.4e-09 35.7 17.4 0.006 17.1 0.3 8.9 8 2 1 9 9 9 2 HEAT-like repeat IFRD PF05004.13 CDS33034.2 - 0.0018 17.4 10.5 0.27 10.3 0.2 4.6 2 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Arm_vescicular PF18770.1 CDS33034.2 - 0.021 14.8 4.0 3.6 7.6 0.1 2.9 3 0 0 3 3 3 0 Armadillo tether-repeat of vescicular transport factor SpoVIF PF14069.6 CDS33034.2 - 0.028 14.2 0.2 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Stage VI sporulation protein F Big_2 PF02368.18 CDS33034.2 - 0.086 12.7 0.1 22 5.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) BESS PF02944.20 CDS33034.2 - 0.13 12.1 3.5 93 3.0 0.2 4.4 4 0 0 4 4 4 0 BESS motif Pkinase_Tyr PF07714.17 CDS33035.1 - 1.2e-93 313.1 0.0 1.6e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS33035.1 - 5.6e-45 153.8 0.0 8.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS33035.1 - 5.6e-19 68.0 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CDS33035.1 - 1.7e-13 49.9 0.0 3.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS33035.1 - 1.1e-11 44.4 0.1 2.9e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS33035.1 - 5.5e-09 35.6 0.1 4.3e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_16 PF18348.1 CDS33035.1 - 0.015 15.1 0.2 0.034 14.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Kinase-like PF14531.6 CDS33035.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CDS33035.1 - 0.056 12.4 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain NDUF_B6 PF09782.9 CDS33036.1 - 4.2e-21 75.7 0.0 5.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit zf-C2HC PF01530.18 CDS33037.1 - 1e-24 86.4 29.6 5.3e-13 48.9 9.7 3.2 4 0 0 4 4 4 2 Zinc finger, C2HC type zf-RAG1 PF10426.9 CDS33037.1 - 0.086 13.0 0.5 2.2 8.5 0.1 2.7 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain IBR PF01485.21 CDS33037.1 - 0.92 9.8 4.6 14 6.0 0.2 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TH1 PF04858.13 CDS33038.1 - 1.3e-71 242.0 0.8 9.1e-59 199.6 0.1 2.0 2 0 0 2 2 2 2 TH1 protein 7tm_1 PF00001.21 CDS33039.1 - 3.5e-43 147.8 18.3 4.2e-43 147.6 18.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS33039.1 - 7.7e-08 32.0 17.0 9.1e-08 31.8 17.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS33039.1 - 8.4e-06 25.6 21.5 1.2e-05 25.1 20.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx RRM_1 PF00076.22 CDS33040.1 - 2.2e-41 139.5 0.0 2.5e-22 78.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDS33040.1 - 6.8e-19 68.8 0.2 2.8e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 CDS33040.1 - 0.057 13.4 0.0 7.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDS33040.1 - 0.18 12.0 0.0 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Thioredoxin PF00085.20 CDS33041.1 - 8.3e-06 25.7 0.1 2.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Phosducin PF02114.16 CDS33041.1 - 1.4e-05 24.2 0.1 1.9e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin PDCD2_C PF04194.13 CDS33042.1 - 2.2e-35 122.3 0.4 6.7e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 CDS33042.1 - 1e-06 28.7 22.3 2.4e-06 27.5 18.7 2.6 2 0 0 2 2 2 1 MYND finger zf-ANAPC11 PF12861.7 CDS33042.1 - 0.85 9.7 11.5 0.12 12.4 7.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.6 CDS33044.2 - 4.2e-26 90.2 49.8 8.1e-07 29.2 0.7 6.8 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 CDS33044.2 - 5.8e-16 58.0 52.8 0.00011 22.5 3.1 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33044.2 - 1.7e-12 47.0 50.9 0.0022 18.7 2.0 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS33044.2 - 2.8e-06 27.5 28.8 0.058 13.7 0.0 6.8 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS33044.2 - 0.0071 16.3 43.2 0.41 10.7 0.2 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS33044.2 - 0.0074 16.0 0.3 0.0074 16.0 0.3 4.9 5 0 0 5 5 5 1 zinc-finger C2H2-type PyrI_C PF02748.15 CDS33044.2 - 0.37 10.7 13.0 3.1 7.8 0.6 4.3 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 CDS33044.2 - 0.84 10.4 18.2 1.1 10.1 8.3 3.9 4 1 1 5 5 5 0 zinc-ribbon family zf-CHCC PF10276.9 CDS33044.2 - 1.1 9.4 19.7 2.6 8.2 1.0 4.5 5 0 0 5 5 5 0 Zinc-finger domain zf-Di19 PF05605.12 CDS33044.2 - 5.8 7.3 34.9 8.1 6.8 5.4 4.8 1 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding TINF2_N PF14973.6 CDS33045.2 - 2 8.8 18.9 0.097 13.0 2.0 3.6 3 1 1 4 4 4 0 TERF1-interacting nuclear factor 2 N-terminus LemA PF04011.12 CDS33045.2 - 9.5 6.1 17.6 0.05 13.4 2.1 3.5 1 1 3 4 4 4 0 LemA family Biotin_lipoyl PF00364.22 CDS33046.1 - 3.4e-14 52.4 0.2 4.1e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme zf-CCCH_8 PF18633.1 CDS33046.1 - 0.27 11.4 0.7 0.49 10.6 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 ADIP PF11559.8 CDS33047.1 - 0.0075 16.4 0.3 0.012 15.7 0.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.11 CDS33047.1 - 0.0095 15.8 4.9 0.3 11.0 0.2 2.9 3 0 0 3 3 3 2 Lung surfactant protein D coiled-coil trimerisation Csm1_N PF18504.1 CDS33047.1 - 0.11 12.8 1.9 11 6.4 0.9 2.6 2 1 1 3 3 3 0 Csm1 N-terminal domain KASH_CCD PF14662.6 CDS33047.1 - 1.2 9.0 5.2 1.2 8.9 0.6 2.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 CDS33047.1 - 6.7 6.7 11.8 10 6.1 0.8 3.2 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Metallophos PF00149.28 CDS33049.1 - 4.5e-35 122.0 0.0 6.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NTF2 PF02136.20 CDS33050.1 - 2.3e-21 76.6 0.0 2.6e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RHD_dimer PF16179.5 CDS33052.1 - 3.6e-21 75.1 0.0 1.1e-12 47.9 0.0 3.6 2 1 0 2 2 2 2 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 CDS33052.1 - 5.7e-14 52.4 0.0 2.4e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Rel homology DNA-binding domain Gar1 PF04410.14 CDS33053.1 - 5e-27 94.6 0.0 6.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PRC PF05239.16 CDS33053.1 - 0.072 13.2 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 PRC-barrel domain CH PF00307.31 CDS33054.1 - 1.3e-17 64.0 0.1 3.8e-17 62.4 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS33054.1 - 5.3e-06 26.2 0.1 1.9e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain Spc7 PF08317.11 CDS33054.1 - 3 6.6 34.9 0.27 10.1 14.1 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CDS33054.1 - 3.9 7.7 43.1 0.079 13.2 5.7 4.5 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 CDS33054.1 - 4.8 6.4 31.1 0.03 13.6 2.8 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CDS33054.1 - 6.2 6.9 45.3 2.2 8.4 8.9 5.4 4 2 0 4 4 4 0 TPR/MLP1/MLP2-like protein ERCC3_RAD25_C PF16203.5 CDS33055.1 - 6.5e-118 392.4 0.2 1.2e-117 391.5 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CDS33055.1 - 7.6e-33 113.4 0.0 3.8e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS33055.1 - 6.7e-16 58.8 0.0 1.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS33055.1 - 2.6e-11 43.8 0.1 1.1e-10 41.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDS33055.1 - 9.5e-06 24.6 0.0 3.4e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 CDS33055.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-H2C2_2 PF13465.6 CDS33056.1 - 5.2e-28 96.2 52.2 1e-09 38.3 0.5 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.26 CDS33056.1 - 1.2e-22 79.0 54.5 1.2e-06 28.7 2.6 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33056.1 - 1.8e-22 78.1 49.4 0.00024 21.7 2.2 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS33056.1 - 8.5e-13 48.2 26.4 0.032 14.5 0.1 6.4 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CDS33056.1 - 0.004 16.9 0.5 0.004 16.9 0.5 4.8 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-Di19 PF05605.12 CDS33056.1 - 0.01 16.1 33.6 0.29 11.5 4.1 5.0 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf_Hakai PF18408.1 CDS33056.1 - 0.035 13.8 0.7 0.035 13.8 0.7 3.1 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 CDS33056.1 - 0.045 13.8 40.2 1.1 9.3 0.1 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger Spt46 PF17734.1 CDS33056.1 - 0.11 12.2 0.2 0.11 12.2 0.2 3.4 2 1 1 4 4 4 0 Spermatogenesis-associated protein 46 zinc_ribbon_9 PF14369.6 CDS33056.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.9 5 0 0 5 5 5 0 zinc-ribbon PyrI_C PF02748.15 CDS33056.1 - 1.6 8.7 15.2 21 5.1 0.4 5.3 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 CDS33056.1 - 4.2 7.8 27.1 1 9.7 0.9 5.7 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 CDS33056.1 - 7.8 6.6 17.9 14 5.9 1.2 4.8 5 0 0 5 5 5 0 Zinc-finger domain Pyr_redox_2 PF07992.14 CDS33057.1 - 1.4e-09 37.6 0.0 1.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CDS33057.1 - 9.1e-05 21.1 0.0 0.00015 20.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 CDS33057.1 - 0.024 14.6 0.0 0.3 11.1 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CDS33057.1 - 0.025 15.0 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDS33057.1 - 0.12 12.4 0.1 35 4.4 0.0 3.3 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Phos_pyr_kin PF08543.12 CDS33060.1 - 5.2e-08 32.6 0.0 6.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CDS33060.1 - 0.0002 20.7 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase BTB PF00651.31 CDS33061.1 - 4.3e-19 68.8 1.1 7.2e-19 68.1 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 CDS33061.1 - 3e-08 33.7 1.4 8.6e-08 32.2 1.4 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch PHR PF08005.12 CDS33061.1 - 3.7e-08 34.2 1.5 0.00048 20.8 0.0 3.5 2 1 1 3 3 3 2 PHR domain WD40 PF00400.32 CDS33062.1 - 1.4e-08 35.3 16.7 0.0024 18.7 2.6 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat HTH_32 PF13565.6 CDS33062.1 - 1.8e-06 28.5 0.2 5.5e-06 26.9 0.2 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 CDS33062.1 - 0.01 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CDS33062.1 - 0.013 15.3 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.10 CDS33062.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain SpoIIID PF12116.8 CDS33062.1 - 0.044 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_AsnC-type PF13404.6 CDS33062.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 CDS33062.1 - 0.12 12.4 0.8 3.1 7.9 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn helix zf-CCCH PF00642.24 CDS33063.1 - 0.017 15.0 6.4 0.024 14.6 0.6 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Transposase_1 PF01359.18 CDS33064.1 - 2.5e-10 40.0 0.1 2e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 Transposase (partial DDE domain) Ank_2 PF12796.7 CDS33066.1 - 2.9e-21 75.8 1.3 1.9e-06 28.3 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDS33066.1 - 2.1e-20 72.2 6.3 1.1e-05 25.6 0.5 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CDS33066.1 - 7.6e-18 64.6 3.3 0.0002 21.9 0.1 5.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS33066.1 - 2.9e-15 56.1 2.3 8.6e-05 22.8 0.2 5.4 4 2 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33066.1 - 3.8e-15 54.5 6.7 0.00018 21.7 0.1 7.4 7 1 0 7 7 7 4 Ankyrin repeat zf-MYND PF01753.18 CDS33066.1 - 7.4e-07 29.2 11.6 1.8e-06 27.9 11.6 1.7 1 0 0 1 1 1 1 MYND finger CsgA PF17334.2 CDS33066.1 - 0.34 11.7 2.6 6 7.7 0.0 2.5 2 0 0 2 2 2 0 Minor curli fiber component A WD40 PF00400.32 CDS33068.1 - 1.2e-11 45.0 19.7 0.00036 21.3 0.6 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CDS33068.1 - 3.3e-08 33.0 11.8 9.2e-08 31.6 11.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF1039 PF06287.11 CDS33068.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) zf-rbx1 PF12678.7 CDS33068.1 - 0.43 10.9 10.6 0.17 12.2 7.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zinc_ribbon_16 PF17034.5 CDS33068.1 - 5.9 7.1 12.4 87 3.3 12.3 3.0 2 1 0 2 2 2 0 Zinc-ribbon like family Iso_dh PF00180.20 CDS33069.1 - 1.1e-68 231.9 0.1 1.4e-68 231.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Dak1_2 PF13684.6 CDS33069.1 - 0.077 12.1 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Dihydroxyacetone kinase family Glypican PF01153.19 CDS33070.1 - 8.7e-09 34.7 0.1 5.8e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Glypican Pkinase PF00069.25 CDS33071.1 - 3.8e-16 59.3 0.0 9.9e-16 57.9 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33071.1 - 8.1e-10 38.4 0.0 4.6e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDS33071.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.22 CDS33072.1 - 4.5e-12 45.6 0.0 8.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS33072.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CDS33072.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain RRM_7 PF16367.5 CDS33072.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif AAA_6 PF12774.7 CDS33073.1 - 2.4e-146 486.9 0.0 1e-145 484.8 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDS33073.1 - 3.6e-112 375.4 15.8 3.6e-112 375.4 15.8 3.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CDS33073.1 - 1.7e-94 317.5 3.4 1.7e-94 317.5 3.4 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CDS33073.1 - 4.2e-83 278.7 0.0 1.6e-81 273.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CDS33073.1 - 7.5e-78 260.6 0.4 7.5e-78 260.6 0.4 3.8 4 0 0 4 4 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CDS33073.1 - 7.7e-75 251.9 0.0 2.2e-74 250.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDS33073.1 - 6.7e-66 221.2 0.1 3.4e-61 205.9 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CDS33073.1 - 2.1e-47 161.0 0.3 1e-46 158.7 0.3 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CDS33073.1 - 5.1e-43 147.4 21.8 1.3e-24 86.9 0.2 2.7 2 1 1 3 3 3 2 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CDS33073.1 - 2.1e-35 121.4 0.0 3.9e-34 117.3 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDS33073.1 - 3.3e-25 88.7 0.0 1.1e-06 28.7 0.0 5.7 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CDS33073.1 - 3.1e-18 65.8 0.2 1.8e-17 63.3 0.2 2.4 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CDS33073.1 - 4.3e-12 46.2 0.1 4.7e-10 39.6 0.1 3.2 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CDS33073.1 - 3.8e-09 37.0 1.6 0.19 12.2 0.0 5.6 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS33073.1 - 5.5e-09 36.4 1.5 0.18 12.1 0.0 5.8 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 CDS33073.1 - 0.002 17.3 0.5 0.089 11.8 0.1 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_16 PF13191.6 CDS33073.1 - 0.003 17.9 6.9 11 6.3 0.0 6.4 5 2 1 6 6 6 0 AAA ATPase domain AAA_18 PF13238.6 CDS33073.1 - 0.016 15.7 0.0 6.2 7.4 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CDS33073.1 - 0.15 12.4 0.7 62 3.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain Ribosomal_L22 PF00237.19 CDS33073.1 - 0.48 10.7 4.8 2.7 8.3 4.8 2.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e SlyX PF04102.12 CDS33073.1 - 3 8.5 17.0 6.2 7.5 4.7 4.5 3 0 0 3 3 3 0 SlyX Tup_N PF08581.10 CDS33073.1 - 5.5 7.4 8.6 1.1 9.6 1.2 4.0 3 0 0 3 3 2 0 Tup N-terminal PNP_UDP_1 PF01048.20 CDS33074.1 - 4.7e-48 163.5 0.1 5.3e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DisA_N PF02457.16 CDS33074.1 - 0.099 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding G-patch PF01585.23 CDS33074.1 - 0.13 12.2 0.2 0.36 10.7 0.2 1.7 1 0 0 1 1 1 0 G-patch domain A_deaminase PF00962.22 CDS33076.1 - 1.9e-68 231.3 0.2 2.2e-68 231.0 0.2 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CDS33076.1 - 0.00071 19.0 1.4 0.0012 18.2 1.4 1.4 1 1 0 1 1 1 1 Amidohydrolase family AFOR_N PF02730.15 CDS33076.1 - 0.036 13.9 0.2 0.055 13.3 0.2 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Med21 PF11221.8 CDS33077.1 - 2.6e-17 63.4 1.1 2.6e-17 63.4 1.1 1.6 2 0 0 2 2 2 1 Subunit 21 of Mediator complex CHD5 PF04420.14 CDS33077.1 - 7.3e-07 29.2 0.1 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 CHD5-like protein ATG101 PF07855.12 CDS33077.1 - 0.0057 16.7 0.0 0.23 11.4 0.0 2.4 1 1 1 2 2 2 1 Autophagy-related protein 101 Peptidase_C33 PF05412.12 CDS33077.1 - 0.11 12.5 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase GCOM2 PF15328.6 CDS33078.1 - 0.087 13.2 0.8 0.22 11.9 0.8 1.7 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Bax1-I PF01027.20 CDS33079.1 - 8.2e-48 163.0 32.3 9.4e-48 162.8 32.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4079 PF13301.6 CDS33079.1 - 7.4 6.7 8.1 2.6 8.2 3.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) CPBP PF02517.16 CDS33080.1 - 2.2e-16 60.0 8.5 2.2e-16 60.0 8.5 1.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease CBF PF03914.17 CDS33081.1 - 6.5e-18 65.3 0.0 1.8e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 CBF/Mak21 family E2F_TDP PF02319.20 CDS33082.1 - 1.4e-23 82.7 0.2 3.5e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 CDS33082.1 - 2.9e-23 82.0 0.9 4.9e-23 81.3 0.4 1.6 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain Baculo_PEP_C PF04513.12 CDS33082.1 - 0.036 14.1 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus kleA_kleC PF17383.2 CDS33082.1 - 0.082 13.2 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A XhlA PF10779.9 CDS33082.1 - 1.9 8.8 9.0 0.21 11.8 3.2 2.3 3 0 0 3 3 3 0 Haemolysin XhlA Nop10p PF04135.12 CDS33083.1 - 8.6e-17 60.9 0.1 1.2e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CaKB PF03185.15 CDS33084.1 - 3.3e-08 33.4 2.5 0.00061 19.5 0.5 2.2 1 1 1 2 2 2 2 Calcium-activated potassium channel, beta subunit SKG6 PF08693.10 CDS33084.1 - 0.00021 20.6 0.2 0.00021 20.6 0.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain adh_short PF00106.25 CDS33085.1 - 4.9e-31 107.7 0.1 9.1e-24 84.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33085.1 - 1.5e-22 80.3 0.0 6e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS33085.1 - 1.1e-06 28.7 0.1 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 CDS33085.1 - 0.00021 21.6 0.0 0.00038 20.7 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 CDS33085.1 - 0.13 11.8 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 CDS33086.1 - 2.9e-33 115.0 0.3 1.8e-25 89.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33086.1 - 3.3e-27 95.6 0.0 2.2e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS33086.1 - 2.3e-06 27.6 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDS33086.1 - 0.00016 21.2 0.3 0.00063 19.3 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDS33086.1 - 0.00025 21.3 0.0 0.00041 20.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_10 PF00331.20 CDS33086.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 K_channel_TID PF07941.11 CDS33087.1 - 0.14 12.6 0.3 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SLC12 PF03522.15 CDS33087.1 - 0.16 10.9 7.2 0.17 10.8 7.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4820 PF16091.5 CDS33087.1 - 0.44 9.9 9.5 0.25 10.7 7.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) DUF1980 PF09323.10 CDS33087.1 - 1.2 9.0 6.9 3 7.7 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 CDS33087.1 - 1.4 8.9 5.5 1.5 8.9 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDS33087.1 - 2.3 6.9 9.9 2.5 6.8 9.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CDS33087.1 - 2.6 6.1 8.7 2.7 6.0 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.19 CDS33087.1 - 2.7 6.8 7.1 3.3 6.5 7.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NPR3 PF03666.13 CDS33087.1 - 6.7 5.4 13.1 7.6 5.2 13.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LRR_8 PF13855.6 CDS33090.1 - 9.2e-17 60.6 6.0 2.6e-15 55.9 0.4 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 CDS33090.1 - 1.3e-07 31.7 0.2 3.2e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CDS33090.1 - 5.2e-06 26.7 2.3 0.0018 18.6 0.4 4.0 2 2 4 6 6 6 3 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 CDS33090.1 - 7.1e-05 23.3 0.1 0.00027 21.5 0.1 2.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS33090.1 - 0.0037 17.3 0.1 0.0081 16.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS33090.1 - 0.0058 17.0 1.4 0.054 13.8 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain LRR_1 PF00560.33 CDS33090.1 - 0.013 15.9 5.5 12 6.9 0.0 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat FAM176 PF14851.6 CDS33090.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 FAM176 family APG9 PF04109.16 CDS33091.1 - 2.5e-137 458.8 8.3 3e-137 458.5 8.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF1218 PF06749.12 CDS33091.1 - 1.1 9.8 3.2 16 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) LicD PF04991.13 CDS33094.1 - 3e-11 43.9 1.2 7.4e-06 26.3 0.1 3.0 2 1 1 3 3 3 3 LicD family MMR_HSR1 PF01926.23 CDS33096.1 - 1.5e-07 31.5 0.0 1.3e-06 28.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDS33096.1 - 0.00099 18.7 0.0 0.42 10.1 0.0 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CDS33096.1 - 0.0061 16.6 0.5 0.022 14.8 0.0 2.2 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CDS33096.1 - 0.01 15.4 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 CDS33096.1 - 0.011 15.9 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDS33096.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 CDS33096.1 - 0.15 11.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Ras family Cadherin PF00028.17 CDS33097.1 - 4.8e-85 280.2 0.8 1.5e-21 76.6 0.0 9.2 8 1 0 8 8 8 8 Cadherin domain Cadherin_3 PF16184.5 CDS33097.1 - 1.7e-11 44.1 5.4 0.0022 18.0 0.0 6.5 7 0 0 7 7 7 3 Cadherin-like RET_CLD1 PF17756.1 CDS33097.1 - 8.9e-09 35.7 0.0 0.046 14.0 0.0 4.6 4 0 0 4 4 4 3 RET Cadherin like domain 1 Cadherin_2 PF08266.12 CDS33097.1 - 0.00064 19.5 0.0 5.7 6.9 0.0 4.0 4 0 0 4 4 4 2 Cadherin-like Cadherin_4 PF17803.1 CDS33097.1 - 0.085 13.5 15.8 1.1 10.0 0.3 5.0 5 0 0 5 5 5 0 Bacterial cadherin-like domain Orf78 PF06024.12 CDS33097.1 - 0.11 12.9 1.3 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Skp1 PF01466.19 CDS33098.1 - 1.4e-10 41.1 0.9 2.1e-10 40.6 0.9 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDS33098.1 - 0.0024 18.0 0.1 0.0043 17.2 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain EF-hand_7 PF13499.6 CDS33098.1 - 0.025 15.0 0.8 0.048 14.1 0.8 1.4 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_M29 PF02073.15 CDS33100.1 - 0.083 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) DUF2071 PF09844.9 CDS33100.1 - 1.3 8.6 4.4 2.3 7.8 3.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (COG2071) Lig_chan PF00060.26 CDS33101.1 - 4.6e-16 59.0 0.3 9e-16 58.0 0.3 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Thioredoxin_9 PF14595.6 CDS33101.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin CcmD PF04995.14 CDS33101.1 - 6.9 6.8 6.4 0.51 10.5 0.2 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Lig_chan PF00060.26 CDS33102.1 - 2e-13 50.5 1.4 3e-13 49.9 1.4 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel DUF3592 PF12158.8 CDS33102.1 - 0.083 12.9 0.5 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) MBOAT PF03062.19 CDS33103.1 - 1.5e-24 87.0 10.7 2.1e-24 86.5 10.7 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_H PF00075.24 CDS33104.1 - 3.8e-12 46.6 0.1 5.2e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 CDS33105.1 - 2.6e-27 95.8 0.1 3.2e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1289 PF06945.13 CDS33106.1 - 0.19 11.6 0.4 0.48 10.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) SLATT_5 PF18160.1 CDS33108.1 - 0.11 11.9 1.1 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Glyco_transf_25 PF01755.17 CDS33109.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) XPG_I PF00867.18 CDS33110.1 - 2.4e-20 72.7 0.0 6.6e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDS33110.1 - 1.3e-11 44.8 0.0 4.8e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain Chromo_2 PF18704.1 CDS33110.1 - 1.4e-10 41.3 0.0 3.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 UPF0047 PF01894.17 CDS33111.1 - 5.1e-37 126.6 0.0 5.8e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GCP_C_terminal PF04130.13 CDS33112.1 - 1.9e-26 93.2 1.2 1.9e-26 93.2 1.2 2.9 2 2 1 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDS33112.1 - 2.7e-13 50.3 0.5 6.3e-13 49.0 0.5 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal TPH PF13868.6 CDS33112.1 - 0.0015 17.1 29.7 0.0022 16.6 29.7 1.2 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain MAT1 PF06391.13 CDS33112.1 - 0.82 9.5 14.4 2.7 7.8 14.4 1.8 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TM2 PF05154.16 CDS33113.1 - 8.9e-14 51.6 13.2 1.4e-13 51.0 13.2 1.3 1 0 0 1 1 1 1 TM2 domain PAXIP1_C PF15364.6 CDS33114.1 - 1.6e-16 60.8 0.2 1.6e-16 60.8 0.2 2.1 2 0 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein zf_Hakai PF18408.1 CDS33116.1 - 6.7e-19 67.3 1.3 6.7e-19 67.3 1.3 2.6 3 0 0 3 3 3 1 C2H2 Hakai zinc finger domain zf-C3HC4 PF00097.25 CDS33116.1 - 0.0054 16.6 8.1 0.015 15.2 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS33116.1 - 0.012 15.4 8.7 0.012 15.4 8.7 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDS33116.1 - 0.033 14.0 7.7 0.085 12.7 7.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CDS33116.1 - 0.071 13.6 1.7 0.071 13.6 1.7 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Macoilin PF09726.9 CDS33116.1 - 0.18 10.4 2.6 0.18 10.3 2.6 1.1 1 0 0 1 1 1 0 Macoilin family zf-RING_2 PF13639.6 CDS33116.1 - 0.25 11.7 11.5 0.73 10.2 11.5 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CDS33116.1 - 1.1 9.4 9.8 3.1 7.9 9.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_4 PF13894.6 CDS33116.1 - 3.4 8.7 24.1 0.57 11.2 1.0 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Cyclin_N PF00134.23 CDS33118.1 - 2.1e-11 43.7 0.0 3.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain O-FucT PF10250.9 CDS33120.1 - 4.5e-42 144.9 0.0 5.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BCIP PF13862.6 CDS33121.1 - 6.6e-34 117.5 0.2 8.2e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein UNC-50 PF05216.13 CDS33122.1 - 1.1e-78 263.8 19.7 1.3e-78 263.6 19.7 1.1 1 0 0 1 1 1 1 UNC-50 family Pkinase PF00069.25 CDS33123.1 - 2.8e-66 223.6 0.0 4e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33123.1 - 2.1e-30 105.9 0.0 2.9e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS33123.1 - 1.5e-05 24.0 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDS33123.1 - 0.0054 16.1 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDS33123.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DnaJ PF00226.31 CDS33124.1 - 3.2e-25 88.0 0.4 4.8e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.16 CDS33124.1 - 0.12 10.9 10.4 0.13 10.7 10.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RWD PF05773.22 CDS33125.1 - 2.1e-21 76.3 0.9 4.7e-21 75.2 0.9 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CDS33125.1 - 1.2e-08 35.4 3.6 1.2e-08 35.4 3.6 1.7 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 CREPT PF16566.5 CDS33125.1 - 0.13 12.5 2.8 0.14 12.3 1.6 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CLTH PF10607.9 CDS33126.1 - 6.9e-08 32.5 0.0 6.7e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CDS33126.1 - 9.1e-06 25.6 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 CDS33126.1 - 0.029 14.2 0.3 0.088 12.6 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Neur_chan_LBD PF02931.23 CDS33127.2 - 2.1e-09 37.1 1.0 2.8e-09 36.8 0.1 1.6 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain HTH_11 PF08279.12 CDS33127.2 - 0.0067 16.4 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 HTH domain Neur_chan_memb PF02932.16 CDS33127.2 - 0.0077 16.3 7.0 0.0077 16.3 7.0 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region HTH_24 PF13412.6 CDS33127.2 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 CDS33127.2 - 0.11 12.4 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 CDS33127.2 - 0.11 12.5 0.1 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain ANT PF03374.14 CDS33127.2 - 0.17 12.2 0.0 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain DUF475 PF04332.15 CDS33127.2 - 0.43 10.3 3.5 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF475) adh_short PF00106.25 CDS33128.1 - 1.5e-30 106.1 0.2 2.6e-17 62.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33128.1 - 1.5e-20 73.7 0.0 2.5e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS33128.1 - 1.2e-11 44.8 0.3 3.5e-09 36.8 0.1 2.1 2 0 0 2 2 2 2 KR domain HTH_16 PF12645.7 CDS33128.1 - 0.078 13.0 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain GDP_Man_Dehyd PF16363.5 CDS33128.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF347 PF03988.12 CDS33128.1 - 0.28 11.4 3.8 0.83 9.9 0.1 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) FYRC PF05965.14 CDS33130.1 - 5.1e-25 87.5 0.0 1.5e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CDS33130.1 - 5.8e-20 70.9 0.3 1.4e-19 69.7 0.3 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus SET PF00856.28 CDS33130.1 - 6.1e-18 65.8 0.3 2.5e-17 63.8 0.3 2.2 1 1 0 1 1 1 1 SET domain zf-HC5HC2H PF13771.6 CDS33130.1 - 2.8e-07 30.7 10.4 3.2e-07 30.5 7.5 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDS33130.1 - 1.6e-06 28.2 13.0 4.3e-06 26.8 10.4 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain DUP PF00674.18 CDS33130.1 - 0.025 14.7 0.3 0.64 10.2 0.1 2.7 3 0 0 3 3 3 0 DUP family Ribosomal_S26e PF01283.19 CDS33131.1 - 0.012 16.0 0.1 0.013 15.9 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein S26e RNase_H PF00075.24 CDS33132.1 - 3.3e-08 33.8 0.0 4.5e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CDS33132.1 - 0.0022 17.8 0.2 0.0036 17.1 0.2 1.5 1 1 0 1 1 1 1 Reverse transcriptase-like IMD PF08397.11 CDS33132.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Exo_endo_phos_2 PF14529.6 CDS33133.1 - 1.9e-07 30.9 0.9 6.2e-07 29.3 0.3 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Ig_3 PF13927.6 CDS33135.1 - 1.8e-77 256.0 2.6 1.7e-16 60.6 0.0 6.6 6 1 0 6 6 5 5 Immunoglobulin domain I-set PF07679.16 CDS33135.1 - 4.6e-76 251.0 0.0 2.4e-19 69.2 0.0 6.0 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS33135.1 - 1.4e-57 192.0 0.6 1.4e-14 54.2 0.1 5.6 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 CDS33135.1 - 7.6e-52 173.4 0.2 2.6e-12 46.7 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.17 CDS33135.1 - 2e-31 108.4 4.3 9.1e-05 22.6 0.2 8.3 5 3 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.12 CDS33135.1 - 2.3e-15 56.4 0.2 0.029 14.4 0.0 5.0 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CDS33135.1 - 7.9e-14 51.0 0.0 0.13 11.9 0.0 5.2 5 0 0 5 5 5 4 Immunoglobulin domain fn3 PF00041.21 CDS33135.1 - 1.1e-13 51.3 0.0 9.8e-08 32.2 0.0 3.8 3 0 0 3 3 3 2 Fibronectin type III domain Ig_4 PF16680.5 CDS33135.1 - 1.2e-07 31.8 0.1 3.4 8.0 0.0 5.4 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CDS33135.1 - 3.1e-07 30.3 0.1 2.2 8.4 0.0 5.1 5 0 0 5 5 5 2 Izumo-like Immunoglobulin domain Ig_C17orf99 PF17736.1 CDS33135.1 - 2.2e-06 27.6 0.2 6.6 6.8 0.0 5.9 4 2 0 5 5 5 1 C17orf99 Ig domain C2-set PF05790.15 CDS33135.1 - 1.7e-05 24.9 0.0 0.083 13.1 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C2-set domain Herpes_gE PF02480.16 CDS33135.1 - 0.00029 19.7 0.0 3.1 6.4 0.0 4.2 3 1 0 5 5 5 2 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 CDS33135.1 - 0.12 13.3 0.0 0.29 12.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lep_receptor_Ig PF06328.11 CDS33135.1 - 0.15 12.1 0.2 7.3 6.6 0.0 3.4 4 0 0 4 4 4 0 Ig-like C2-type domain XK-related PF09815.9 CDS33136.1 - 4.7e-28 98.2 9.7 1.1e-27 97.0 9.7 1.6 1 1 0 1 1 1 1 XK-related protein Mito_carr PF00153.27 CDS33138.1 - 8.7e-65 214.7 5.1 1.8e-23 82.3 0.0 3.6 3 1 1 4 4 4 3 Mitochondrial carrier protein p25-alpha PF05517.12 CDS33139.1 - 6.6e-33 114.1 4.9 1e-32 113.4 4.9 1.2 1 0 0 1 1 1 1 p25-alpha DUF3808 PF10300.9 CDS33140.2 - 4.6e-112 375.2 3.6 7.2e-112 374.6 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 CDS33140.2 - 0.021 14.2 0.3 1.9 7.8 0.1 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_19 PF14559.6 CDS33140.2 - 0.089 13.3 1.5 0.64 10.6 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS33140.2 - 0.2 11.9 2.2 3.3 8.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ApeC PF16977.5 CDS33141.1 - 2.7e-55 187.5 25.8 6.3e-24 85.1 0.0 9.8 8 3 2 10 10 10 7 C-terminal domain of apextrin Kringle PF00051.18 CDS33141.1 - 2.6e-24 85.3 16.6 3.8e-15 55.9 5.9 3.8 2 1 0 2 2 2 2 Kringle domain EGF_3 PF12947.7 CDS33141.1 - 1.8e-08 34.4 30.8 1.5e-05 25.1 3.9 3.8 3 0 0 3 3 3 2 EGF domain cEGF PF12662.7 CDS33141.1 - 1.5 8.8 27.0 2.1 8.4 1.3 7.7 7 0 0 7 7 7 0 Complement Clr-like EGF-like Antimicrobial25 PF16839.5 CDS33141.1 - 1.7 8.8 8.3 1.4 9.1 4.2 2.9 2 0 0 2 2 2 0 Nematode antimicrobial peptide 7TM_GPCR_Srj PF10319.9 CDS33143.1 - 0.079 12.3 1.0 0.096 12.0 1.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj zf-C2H2_4 PF13894.6 CDS33143.1 - 0.092 13.6 12.6 0.68 10.9 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS33143.1 - 2.3 8.6 14.1 5.5 7.4 3.5 2.2 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) QVR PF17064.5 CDS33144.1 - 0.015 15.5 10.9 0.061 13.6 10.9 1.9 1 1 0 1 1 1 0 Sleepless protein XendoU PF09412.10 CDS33146.1 - 1.5e-78 263.7 0.0 1.9e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Glyco_hydro_38N PF01074.22 CDS33147.1 - 3.3e-88 295.8 1.4 4.7e-88 295.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CDS33147.1 - 1.3e-22 81.0 0.0 4.4e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CDS33147.1 - 5.1e-21 74.6 0.2 1.2e-20 73.4 0.2 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain SIS PF01380.22 CDS33148.1 - 1.9e-58 196.0 0.3 2.7e-31 108.1 0.0 2.8 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CDS33148.1 - 2.9e-18 66.4 0.0 6.1e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDS33148.1 - 4.8e-14 52.3 0.0 1.3e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDS33148.1 - 0.00015 20.8 0.1 0.00062 18.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF1445 PF07286.12 CDS33148.1 - 0.03 14.3 0.0 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1445) DEAD PF00270.29 CDS33149.1 - 1.2e-36 126.1 0.0 2.6e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS33149.1 - 2.7e-26 92.1 0.0 6.1e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WavE PF07507.11 CDS33149.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis AAA_22 PF13401.6 CDS33149.1 - 0.87 9.9 3.2 2.5 8.4 1.4 2.6 1 1 1 2 2 2 0 AAA domain Antimicrobial24 PF16049.5 CDS33150.1 - 0.14 12.2 0.2 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide SAM_2 PF07647.17 CDS33151.1 - 2.8e-08 33.7 0.1 2.2e-05 24.5 0.4 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS33151.1 - 0.00048 20.5 0.0 0.017 15.6 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HTH_3 PF01381.22 CDS33151.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix NPC1_N PF16414.5 CDS33152.1 - 4.3e-18 65.8 10.8 5.4e-18 65.4 10.8 1.1 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Folate_rec PF03024.14 CDS33152.1 - 8.1e-05 22.6 6.1 8.1e-05 22.6 6.1 2.0 1 1 1 2 2 2 1 Folate receptor family DUF5329 PF17263.2 CDS33152.1 - 0.031 14.5 0.0 0.93 9.7 0.0 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5329) zf-C2H2_4 PF13894.6 CDS33153.1 - 2.8e-08 33.9 18.6 0.00058 20.5 0.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS33153.1 - 5.7e-07 29.7 18.5 0.00041 20.7 0.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDS33153.1 - 2.2e-05 24.6 9.1 0.036 14.4 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CDS33153.1 - 0.0001 21.8 2.9 1.5 8.5 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 CDS33153.1 - 0.0048 16.9 5.5 6.5 6.9 0.1 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-H2C2_2 PF13465.6 CDS33153.1 - 0.0099 16.3 18.3 0.087 13.3 2.2 3.8 4 0 0 4 4 4 2 Zinc-finger double domain DZR PF12773.7 CDS33153.1 - 0.01 15.8 8.0 0.17 12.0 3.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_2 PF12756.7 CDS33153.1 - 0.012 15.9 7.2 3.9 7.9 1.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CDS33153.1 - 0.014 15.6 11.2 0.096 13.0 0.8 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CDS33153.1 - 0.018 15.1 8.4 1.6 8.9 2.2 3.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HC5 PF06221.13 CDS33153.1 - 0.021 14.8 6.8 0.4 10.7 0.1 3.1 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_9 PF14369.6 CDS33153.1 - 0.03 14.6 8.0 2.8 8.3 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2_11 PF16622.5 CDS33153.1 - 0.033 14.0 1.2 0.033 14.0 1.2 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 CDS33153.1 - 0.034 14.6 12.3 0.043 14.2 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Endonuclease_7 PF02945.15 CDS33153.1 - 0.053 13.5 5.2 0.38 10.7 5.2 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII FYVE PF01363.21 CDS33153.1 - 0.062 13.4 8.5 1.7 8.8 0.9 3.0 3 0 0 3 3 3 0 FYVE zinc finger zf-C2H2_6 PF13912.6 CDS33153.1 - 0.069 13.2 14.2 0.58 10.2 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 CDS33153.1 - 0.076 13.0 8.0 1.6 8.8 4.2 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 CDS33153.1 - 0.086 12.3 5.3 5.8 6.5 0.1 3.4 4 0 0 4 4 3 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CDS33153.1 - 0.089 12.7 7.2 11 6.0 7.2 2.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain C1_1 PF00130.22 CDS33153.1 - 0.097 12.6 8.7 27 4.7 0.3 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 CDS33153.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 CDS33153.1 - 0.28 11.2 6.1 14 5.7 6.1 2.4 1 1 0 1 1 1 0 zinc-ribbons C1_4 PF07975.12 CDS33153.1 - 0.35 11.1 6.0 14 6.0 3.1 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain zf-TFIIB PF13453.6 CDS33153.1 - 0.41 10.0 3.5 0.22 10.9 0.6 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 CDS33153.1 - 0.61 10.1 11.5 2.6 8.0 0.9 3.7 3 1 1 4 4 4 0 zinc-ribbon domain FOXP-CC PF16159.5 CDS33153.1 - 0.61 10.7 4.5 30 5.3 0.1 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF629 PF04780.12 CDS33153.1 - 0.81 8.1 9.1 0.19 10.2 0.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_2 PF13240.6 CDS33153.1 - 2.6 7.9 9.9 1.5 8.7 0.4 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-AN1 PF01428.16 CDS33153.1 - 3.1 8.0 11.4 2.2 8.5 0.2 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger zf-ACC PF17848.1 CDS33153.1 - 3.5 7.8 0.0 3.5 7.8 0.0 2.9 4 0 0 4 4 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 CDS33153.1 - 5.7 6.5 7.0 1.6 8.3 3.4 2.1 2 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.6 CDS33153.1 - 5.9 6.7 8.7 8.2 6.3 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 CDS33153.1 - 6.8 6.8 7.8 10 6.2 2.6 2.7 1 1 1 2 2 2 0 CpXC protein Aa_trans PF01490.18 CDS33154.1 - 2.1e-16 59.6 3.8 2.1e-16 59.6 3.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CAP_GLY PF01302.25 CDS33155.2 - 2.5e-70 232.4 3.5 3e-24 84.8 0.1 3.5 3 0 0 3 3 3 3 CAP-Gly domain Ank PF00023.30 CDS33155.2 - 1.5e-11 44.2 2.2 5.3e-05 23.5 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 CDS33155.2 - 9.6e-10 38.9 0.1 3.1e-07 30.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS33155.2 - 3.3e-07 30.7 0.8 5.6e-06 26.8 0.2 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS33155.2 - 2e-06 27.9 0.5 0.0012 19.2 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33155.2 - 1.7e-05 24.8 3.3 0.0024 18.2 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat PetG PF02529.15 CDS33156.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 CH PF00307.31 CDS33157.1 - 1.9e-12 47.3 0.7 4.2e-12 46.2 0.2 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain ATG16 PF08614.11 CDS33157.1 - 0.0027 18.0 5.1 1 9.6 0.3 3.9 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) Bap31_Bap29_C PF18035.1 CDS33157.1 - 0.17 11.9 0.2 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MPS2 PF17060.5 CDS33157.1 - 0.4 9.9 1.8 2.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 CENP-F_leu_zip PF10473.9 CDS33157.1 - 0.91 9.5 13.9 0.18 11.8 3.7 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 CDS33157.1 - 2.9 7.6 12.3 0.051 13.3 3.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 CDS33157.1 - 4.2 8.0 11.3 18 6.0 0.0 3.6 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec2p PF06428.11 CDS33157.1 - 4.4 7.3 7.7 15 5.7 0.2 3.3 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p FlxA PF14282.6 CDS33157.1 - 4.5 7.3 8.7 29 4.7 0.9 3.6 3 0 0 3 3 3 0 FlxA-like protein SH3_1 PF00018.28 CDS33158.1 - 4.8e-51 170.2 11.5 1.2e-14 53.7 0.2 4.4 4 0 0 4 4 4 4 SH3 domain HS1_rep PF02218.15 CDS33158.1 - 1.3e-50 169.4 25.1 1.8e-19 69.8 2.1 3.6 3 0 0 3 3 3 3 Repeat in HS1/Cortactin SH3_9 PF14604.6 CDS33158.1 - 1.2e-36 124.3 0.8 2.4e-09 36.9 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CDS33158.1 - 7.3e-27 92.8 0.9 3.9e-07 29.7 0.0 4.7 5 0 0 5 5 5 4 Variant SH3 domain TMEM210 PF15195.6 CDS33158.1 - 0.023 15.1 0.2 53 4.3 0.0 3.3 1 1 2 3 3 3 0 TMEM210 family zf-C4 PF00105.18 CDS33159.1 - 8.2e-28 96.7 15.0 1.3e-27 96.0 15.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS33159.1 - 1.2e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor BROMI PF14961.6 CDS33160.2 - 1.4e-86 291.1 6.6 1.6e-47 161.7 1.6 3.4 2 1 0 2 2 2 2 Broad-minded protein fn3 PF00041.21 CDS33160.2 - 1.1e-12 48.2 5.5 0.00021 21.6 0.0 5.6 5 0 0 5 5 5 2 Fibronectin type III domain Ig_3 PF13927.6 CDS33160.2 - 1.4e-07 32.0 0.1 0.0064 17.1 0.0 5.3 4 1 0 4 4 4 2 Immunoglobulin domain I-set PF07679.16 CDS33160.2 - 0.00021 21.3 0.0 1.4 9.1 0.0 3.8 3 0 0 3 3 3 2 Immunoglobulin I-set domain V-set PF07686.17 CDS33160.2 - 0.00092 19.4 0.0 0.6 10.3 0.0 3.6 2 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.25 CDS33160.2 - 0.035 14.3 0.0 1.4 9.1 0.0 3.8 3 1 0 3 3 3 0 Immunoglobulin domain fn3 PF00041.21 CDS33161.1 - 1.7e-09 37.9 0.0 0.00031 21.0 0.0 4.6 5 0 0 5 5 5 2 Fibronectin type III domain PapC_N PF13954.6 CDS33161.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PapC N-terminal domain LRRC37AB_C PF14914.6 CDS33161.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain LSR PF05624.14 CDS33161.1 - 0.71 9.9 4.1 1.7 8.7 4.1 1.6 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Myosin_head PF00063.21 CDS33163.1 - 9.3e-281 932.9 7.0 9.3e-281 932.9 7.0 2.6 2 0 0 2 2 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDS33163.1 - 3.6e-177 591.3 281.1 4.5e-177 591.0 281.1 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CDS33163.1 - 1.7e-12 46.9 3.8 5.3e-12 45.4 3.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.6 CDS33163.1 - 9.2e-07 28.7 47.9 9.2e-07 28.7 47.9 11.1 3 2 4 9 9 8 2 Ciliary protein causing Leber congenital amaurosis disease IQ PF00612.27 CDS33163.1 - 6.1e-05 22.5 1.6 0.0019 17.8 0.1 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif TMF_TATA_bd PF12325.8 CDS33163.1 - 0.0013 18.9 5.6 0.0013 18.9 5.6 17.1 4 2 17 21 21 17 1 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 CDS33163.1 - 0.0018 18.6 17.0 0.0018 18.6 17.0 16.9 4 4 12 17 17 14 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MbeD_MobD PF04899.12 CDS33163.1 - 0.0028 17.7 3.2 0.0028 17.7 3.2 12.6 8 5 7 15 15 13 1 MbeD/MobD like KASH_CCD PF14662.6 CDS33163.1 - 0.0047 16.8 22.1 0.0047 16.8 22.1 10.5 2 1 6 10 10 7 1 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 CDS33163.1 - 0.0054 16.8 9.5 0.0054 16.8 9.5 14.6 3 2 9 14 14 14 7 Protein of unknown function (DUF1664) ATG16 PF08614.11 CDS33163.1 - 0.0056 16.9 266.5 0.15 12.3 18.7 10.8 1 1 8 10 10 9 4 Autophagy protein 16 (ATG16) Hpr_kinase_C PF07475.12 CDS33163.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.7 4 0 0 4 4 3 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 CDS33163.1 - 0.37 11.1 0.0 0.37 11.1 0.0 5.4 5 1 0 5 5 4 0 AAA domain Filament PF00038.21 CDS33163.1 - 1.1 8.7 243.9 0.028 14.0 50.8 9.3 1 1 5 7 7 6 0 Intermediate filament protein Peptidase_M16_M PF16187.5 CDS33164.2 - 3.5e-59 200.4 3.2 6.5e-58 196.2 1.2 2.5 2 0 0 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDS33164.2 - 3.1e-34 118.1 0.1 8.9e-34 116.6 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDS33164.2 - 1.8e-20 73.7 0.1 4.6e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Myosin_tail_1 PF01576.19 CDS33165.1 - 7.6e-08 30.7 6.9 8.1e-08 30.6 6.9 1.0 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.9 CDS33165.1 - 0.00019 21.5 3.8 0.0002 21.4 3.8 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 CDS33165.1 - 0.0023 18.2 1.3 0.0025 18.2 1.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) CENP-Q PF13094.6 CDS33165.1 - 0.011 16.0 2.7 0.011 16.0 2.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4404 PF14357.6 CDS33165.1 - 0.012 16.2 0.6 0.015 15.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Tektin PF03148.14 CDS33165.1 - 0.014 14.2 2.3 0.015 14.1 2.3 1.1 1 0 0 1 1 1 0 Tektin family UPF0242 PF06785.11 CDS33165.1 - 0.021 15.0 1.9 0.022 14.9 1.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fzo_mitofusin PF04799.13 CDS33165.1 - 0.031 13.8 0.7 0.036 13.6 0.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region PKcGMP_CC PF16808.5 CDS33165.1 - 0.032 14.1 2.2 0.032 14.1 2.2 2.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 CDS33165.1 - 0.033 13.7 4.1 0.038 13.5 4.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 CDS33165.1 - 0.047 14.2 4.3 0.05 14.1 4.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Nsp1_C PF05064.13 CDS33165.1 - 0.048 13.5 0.3 0.053 13.3 0.3 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region HIP1_clath_bdg PF16515.5 CDS33165.1 - 0.057 14.0 3.8 0.15 12.7 1.1 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RACo_linker PF17650.1 CDS33165.1 - 0.066 13.1 0.7 0.11 12.3 0.7 1.5 1 1 0 1 1 1 0 RACo linker region DUF724 PF05266.14 CDS33165.1 - 0.29 10.9 3.3 0.28 11.0 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) XhlA PF10779.9 CDS33165.1 - 0.33 11.2 2.1 0.42 10.8 1.9 1.4 1 1 0 1 1 1 0 Haemolysin XhlA betaPIX_CC PF16523.5 CDS33165.1 - 0.42 10.5 7.1 1.5 8.7 2.0 2.0 1 1 1 2 2 2 0 betaPIX coiled coil Yeast-kill-tox PF09207.11 CDS33166.1 - 0.099 13.3 3.4 0.56 10.9 1.8 2.3 2 0 0 2 2 2 0 Yeast killer toxin Ribosomal_L4 PF00573.22 CDS33167.1 - 1.3e-37 129.4 0.5 1.9e-37 128.8 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CDS33167.1 - 6e-23 80.7 4.7 6e-23 80.7 4.7 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain UQ_con PF00179.26 CDS33168.1 - 5.8e-37 126.5 0.1 7.2e-37 126.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Not3 PF04065.15 CDS33169.1 - 9.6e-78 260.8 30.6 9.6e-78 260.8 30.6 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CDS33169.1 - 2.2e-52 176.6 30.0 7.4e-35 119.9 8.1 4.0 3 0 0 3 3 3 2 NOT2 / NOT3 / NOT5 family GCK PF07802.11 CDS33170.1 - 4.8e-06 26.9 0.5 7.4e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 GCK domain DUF1657 PF07870.11 CDS33170.1 - 0.088 12.7 0.1 0.21 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) LRR_4 PF12799.7 CDS33171.1 - 0.00012 22.4 11.8 1.9 9.0 0.2 5.9 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 CDS33171.1 - 0.00028 20.7 0.5 0.00075 19.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDS33171.1 - 0.0043 16.9 1.2 0.01 15.7 1.2 1.7 1 0 0 1 1 1 1 F-box-like Filamin PF00630.19 CDS33172.1 - 1.1e-264 858.1 40.4 7.1e-16 58.9 0.0 22.3 22 0 0 22 22 22 22 Filamin/ABP280 repeat CH PF00307.31 CDS33172.1 - 2.9e-38 130.4 0.5 5.9e-22 77.9 0.6 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 CDS33172.1 - 2.1e-11 43.6 3.1 7.4 6.6 0.1 8.8 8 0 0 8 8 8 3 Y_Y_Y domain Invasin_D3 PF09134.10 CDS33172.1 - 8.6e-07 29.2 5.0 0.46 10.8 0.0 8.0 8 0 0 8 8 8 1 Invasin, domain 3 Big_3_5 PF16640.5 CDS33172.1 - 4.3e-06 26.8 11.8 13 6.1 0.0 9.5 10 0 0 10 10 10 1 Bacterial Ig-like domain (group 3) CAMSAP_CH PF11971.8 CDS33172.1 - 0.0001 22.1 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CopC PF04234.12 CDS33172.1 - 0.04 15.0 0.1 5.5e+02 1.7 0.0 7.1 7 1 0 8 8 8 0 CopC domain CH_2 PF06294.11 CDS33172.1 - 0.061 13.4 0.3 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF5060 PF16586.5 CDS33172.1 - 0.077 13.4 0.0 1.8e+02 2.5 0.0 5.9 8 0 0 8 8 8 0 Domain of unknown function (DUF5060) DEAD PF00270.29 CDS33173.1 - 8.9e-18 64.7 0.0 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS33173.1 - 5.8e-16 58.8 0.0 1.3e-14 54.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS33173.1 - 2.9e-09 37.2 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 CDS33173.1 - 2.5e-07 31.3 0.1 8.3e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 RecQ zinc-binding Ras PF00071.22 CDS33175.1 - 1e-57 194.3 0.2 1.4e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS33175.1 - 2.2e-20 73.0 0.1 4.6e-20 72.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS33175.1 - 1.7e-08 34.1 0.1 2.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDS33175.1 - 0.00038 20.4 1.6 0.16 11.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CDS33175.1 - 0.00047 19.4 0.1 0.15 11.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 CDS33175.1 - 0.0019 17.8 0.1 0.0051 16.4 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDS33175.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1896 PF08989.10 CDS33177.1 - 0.023 14.8 0.3 0.065 13.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) DUF4754 PF15946.5 CDS33177.1 - 0.043 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) Glyco_transf_11 PF01531.16 CDS33177.1 - 0.048 12.9 0.1 0.062 12.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 Retrotrans_gag PF03732.17 CDS33177.1 - 0.055 13.7 0.2 0.1 12.9 0.2 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein Peptidase_S80 PF07230.11 CDS33177.1 - 0.12 10.6 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) DUF2689 PF10894.8 CDS33177.1 - 0.4 10.5 1.3 1.3 8.8 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) zf-C2H2 PF00096.26 CDS33178.1 - 8.2e-11 41.7 20.1 0.0003 21.1 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS33178.1 - 6.9e-09 35.7 15.3 4.4e-06 26.9 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS33178.1 - 1.5e-06 28.5 18.4 0.044 14.6 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.11 CDS33178.1 - 3.6e-05 23.5 0.1 0.0088 15.8 0.1 2.6 2 0 0 2 2 2 1 GAGA factor zf-Di19 PF05605.12 CDS33178.1 - 6.3e-05 23.2 4.8 0.00069 19.9 2.6 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CDS33178.1 - 0.00058 19.6 3.1 0.00058 19.6 3.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.7 CDS33178.1 - 0.0052 17.1 7.3 0.16 12.4 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CDS33178.1 - 0.064 13.9 2.0 0.41 11.3 0.2 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zinc_ribbon_15 PF17032.5 CDS33178.1 - 0.12 13.1 0.7 2.4 8.9 0.6 2.2 1 1 1 2 2 2 0 zinc-ribbon family C1_1 PF00130.22 CDS33178.1 - 0.23 11.3 1.5 9.5 6.2 0.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_9 PF14369.6 CDS33178.1 - 0.67 10.3 3.9 21 5.4 0.3 2.9 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_4 PF13717.6 CDS33178.1 - 0.78 9.7 3.4 4.5 7.3 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 CDS33178.1 - 1.1 9.6 4.7 4.7 7.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.12 CDS33178.1 - 2.8 8.5 6.5 0.46 11.0 0.3 2.2 1 1 1 2 2 2 0 CHY zinc finger FH2 PF02181.23 CDS33181.1 - 6.9e-88 295.3 0.2 6.9e-88 295.3 0.2 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CDS33181.1 - 2.3e-36 125.2 3.5 2.4e-36 125.2 0.0 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CDS33181.1 - 7.6e-22 77.8 0.0 7.6e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Mito_fiss_reg PF05308.11 CDS33181.1 - 7.2e-05 23.0 2.0 0.0002 21.6 2.0 1.7 1 0 0 1 1 1 1 Mitochondrial fission regulator AAA_23 PF13476.6 CDS33181.1 - 0.0093 16.5 9.4 0.42 11.1 1.7 2.7 3 0 0 3 3 3 2 AAA domain PHP_C PF13263.6 CDS33181.1 - 0.023 14.5 0.0 0.081 12.7 0.0 2.0 1 0 0 1 1 1 0 PHP-associated LcrG PF07216.12 CDS33181.1 - 0.07 13.1 0.4 1.3 8.9 0.4 2.8 2 0 0 2 2 2 0 LcrG protein DUF1515 PF07439.11 CDS33181.1 - 0.12 12.4 0.1 4.8 7.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Drf_DAD PF06345.11 CDS33181.1 - 0.13 12.4 0.0 0.48 10.6 0.0 2.1 1 0 0 1 1 1 0 DRF Autoregulatory Domain YabA PF06156.13 CDS33181.1 - 3.8 8.2 6.4 5.6 7.7 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA DUF1779 PF08680.10 CDS33183.1 - 5.3 7.2 10.6 19 5.4 10.6 1.8 1 1 0 1 1 1 0 TATA-box binding Tetraspanin PF00335.20 CDS33184.1 - 2e-12 47.3 14.9 2.8e-12 46.8 14.9 1.2 1 0 0 1 1 1 1 Tetraspanin family Ank_4 PF13637.6 CDS33185.1 - 3.8e-33 113.4 2.2 2.1e-07 31.3 0.0 6.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33185.1 - 6.3e-33 113.2 11.8 1e-14 54.8 0.6 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDS33185.1 - 6.8e-27 92.7 6.8 1.1e-05 25.7 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDS33185.1 - 1e-26 92.7 3.7 1.4e-06 28.5 0.1 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33185.1 - 2.7e-21 73.3 6.3 0.0011 19.3 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat fn3 PF00041.21 CDS33185.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain DUF2002 PF09400.10 CDS33185.1 - 0.099 12.7 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) Ank_4 PF13637.6 CDS33187.1 - 2.8e-15 56.4 1.1 1.6e-11 44.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33187.1 - 6.9e-14 52.2 0.8 1.5e-13 51.1 0.8 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS33187.1 - 1.8e-09 37.6 0.9 2.2e-06 27.8 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDS33187.1 - 4.9e-09 36.2 2.6 0.0016 18.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDS33187.1 - 1.5e-08 34.2 0.6 0.02 15.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Pkinase_Tyr PF07714.17 CDS33187.1 - 7.2e-05 22.2 0.1 0.00048 19.5 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDS33187.1 - 0.0002 20.8 0.0 0.0014 18.1 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 CDS33187.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Filament PF00038.21 CDS33188.2 - 5.2e-36 124.8 53.3 2.2e-34 119.5 53.3 2.1 1 1 0 1 1 1 1 Intermediate filament protein Shugoshin_N PF07558.11 CDS33188.2 - 0.00027 20.7 0.9 0.00027 20.7 0.9 3.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 CDS33188.2 - 0.0042 16.0 51.3 0.04 12.8 13.7 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein APG6_N PF17675.1 CDS33188.2 - 0.0043 17.6 7.6 0.0043 17.6 7.6 5.1 1 1 3 5 5 5 1 Apg6 coiled-coil region SHE3 PF17078.5 CDS33188.2 - 0.24 11.1 42.1 0.039 13.7 10.5 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 CDS33188.2 - 0.37 10.9 50.2 0.16 12.1 12.6 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 CDS33188.2 - 0.52 10.3 60.4 0.14 12.2 14.9 4.1 1 1 2 3 3 2 0 Ciliary rootlet component, centrosome cohesion MCPVI PF02993.14 CDS33188.2 - 1.1 9.0 4.1 0.67 9.8 0.2 2.5 2 1 0 2 2 2 0 Minor capsid protein VI HMG_box PF00505.19 CDS33188.2 - 1.3 9.5 4.8 7.2 7.1 0.1 3.9 3 0 0 3 3 3 0 HMG (high mobility group) box DUF573 PF04504.14 CDS33188.2 - 3.7 8.3 14.7 0.9 10.2 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function, DUF573 Fez1 PF06818.15 CDS33188.2 - 6.6 7.1 53.8 0.44 11.0 23.8 3.5 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 CDS33188.2 - 7.1 6.7 23.2 5.3 7.1 1.5 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Flg_hook PF02120.16 CDS33188.2 - 9.7 6.2 11.5 1.1 9.2 0.1 3.9 4 0 0 4 4 4 0 Flagellar hook-length control protein FliK RRM_1 PF00076.22 CDS33190.1 - 9.4e-22 76.6 2.2 1.5e-16 59.9 0.3 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS33190.1 - 1.5e-06 28.2 0.0 2.1e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif NID PF07292.13 CDS33190.1 - 0.0014 19.2 0.8 0.14 12.8 0.0 2.4 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) PHM7_cyt PF14703.6 CDS33190.1 - 0.046 13.9 0.0 9.9 6.4 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 CDS33190.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif Mito_fiss_reg PF05308.11 CDS33193.1 - 0.21 11.6 2.3 0.2 11.7 2.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.25 CDS33195.1 - 1e-62 211.9 0.0 1.8e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33195.1 - 1.5e-43 149.0 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS33195.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDS33195.1 - 0.012 14.4 2.9 0.014 14.2 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase zf-RING_11 PF17123.5 CDS33196.2 - 3.6e-06 26.6 4.7 1.4e-05 24.7 4.7 2.1 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 CDS33196.2 - 0.0001 22.4 2.1 0.0001 22.4 2.1 2.7 2 1 1 3 3 3 1 FANCL C-terminal domain RWD PF05773.22 CDS33196.2 - 0.00013 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 CDS33196.2 - 0.0018 18.6 16.5 0.0023 18.2 11.0 3.3 2 1 0 2 2 2 1 Ring finger domain Zf_RING PF16744.5 CDS33196.2 - 0.0021 18.1 0.3 0.0021 18.1 0.3 1.9 2 0 0 2 2 2 1 KIAA1045 RING finger zf-RING_UBOX PF13445.6 CDS33196.2 - 0.0042 17.1 2.6 0.0042 17.1 2.6 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDS33196.2 - 0.0094 15.8 1.5 0.0094 15.8 1.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS33196.2 - 0.0099 15.8 8.7 0.0099 15.8 8.7 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDS33196.2 - 0.75 9.7 14.7 1.1 9.2 9.8 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ASC PF00858.24 CDS33197.2 - 1.8e-26 93.1 5.4 3e-26 92.4 5.4 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel AHD PF17793.1 CDS33197.2 - 0.026 14.3 0.1 0.069 13.0 0.1 1.8 1 0 0 1 1 1 0 ANC1 homology domain (AHD) LIP1 PF15904.5 CDS33197.2 - 0.1 12.9 0.6 0.66 10.4 0.1 2.6 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 COMM_domain PF07258.14 CDS33198.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 COMM domain cwf21 PF08312.12 CDS33199.1 - 5.6e-15 55.2 3.4 5.6e-15 55.2 3.4 3.0 3 1 0 3 3 3 1 cwf21 domain DUF4228 PF14009.6 CDS33199.1 - 0.23 11.8 14.8 1.3 9.4 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 CDS33199.1 - 1.2 7.3 22.9 1.6 6.9 22.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5352 PF17303.2 CDS33199.1 - 4.5 7.1 9.1 0.67 9.8 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5352) Arm PF00514.23 CDS33200.1 - 1.1e-14 53.9 24.1 1.7e-06 27.8 0.1 7.4 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CDS33200.1 - 5.6e-09 36.2 2.5 6.3e-05 23.1 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDS33200.1 - 1.6e-08 34.8 0.7 0.009 16.4 0.1 3.1 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 CDS33200.1 - 6.7e-08 32.1 5.1 0.15 12.4 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.20 CDS33200.1 - 1.5e-06 27.1 0.8 0.002 16.8 0.0 2.4 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 CDS33200.1 - 4.8e-06 27.0 12.7 0.15 12.6 0.1 5.6 6 1 0 6 6 6 3 HEAT-like repeat RasGEF_N_2 PF14663.6 CDS33200.1 - 0.036 14.5 0.9 13 6.3 0.1 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 CDS33200.1 - 0.052 13.6 2.0 8.8 6.4 0.3 3.4 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain C2 PF00168.30 CDS33201.2 - 4.9e-45 152.0 0.0 2.7e-22 79.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.16 CDS33201.2 - 1.6e-35 121.9 34.9 8.2e-16 58.3 5.3 4.5 6 0 0 6 6 4 3 FYVE-type zinc finger FYVE PF01363.21 CDS33201.2 - 6.7e-15 55.0 13.9 4.5e-07 29.9 0.4 4.0 4 0 0 4 4 4 2 FYVE zinc finger C1_1 PF00130.22 CDS33201.2 - 0.0091 15.9 19.5 0.077 12.9 3.0 2.9 3 0 0 3 3 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) CEP76-C2 PF15627.6 CDS33201.2 - 0.012 15.1 0.1 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain IBR PF01485.21 CDS33201.2 - 0.013 15.7 15.6 1.3 9.3 3.9 3.8 2 2 0 2 2 2 0 IBR domain, a half RING-finger domain TMCCDC2 PF15844.5 CDS33201.2 - 0.015 15.2 0.3 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 UPF0167 PF03691.14 CDS33201.2 - 0.019 14.8 10.1 0.82 9.4 1.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) NOA36 PF06524.12 CDS33201.2 - 0.019 14.3 13.8 0.11 11.8 0.8 2.7 3 0 0 3 3 2 0 NOA36 protein DUF5600 PF18150.1 CDS33201.2 - 0.039 14.5 0.1 21 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) PNK3P PF08645.11 CDS33201.2 - 0.06 13.0 1.7 28 4.4 0.0 3.6 4 0 0 4 4 4 0 Polynucleotide kinase 3 phosphatase FYDLN_acid PF09538.10 CDS33201.2 - 0.088 13.5 2.2 16 6.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Gemin6 PF06372.12 CDS33201.2 - 0.12 11.9 0.2 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Gemin6 protein Pox_G5 PF04599.12 CDS33201.2 - 0.21 10.6 7.1 3.2 6.7 0.0 3.1 4 0 0 4 4 4 0 Poxvirus G5 protein Exonuc_VII_L PF02601.15 CDS33201.2 - 0.3 10.6 2.8 11 5.5 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit STAT_alpha PF01017.20 CDS33201.2 - 0.54 10.1 5.1 12 5.8 0.4 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain 23S_rRNA_IVP PF05635.11 CDS33201.2 - 0.67 10.3 2.5 30 5.0 0.1 2.5 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein C6_DPF PF10170.9 CDS33201.2 - 0.68 10.3 6.3 16 6.0 0.6 2.9 2 0 0 2 2 2 0 Cysteine-rich domain SpoIISA_toxin PF14171.6 CDS33201.2 - 2.5 7.7 5.2 21 4.7 0.5 2.2 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system zf-C3HC4_4 PF15227.6 CDS33201.2 - 3.9 7.7 8.3 30 4.9 1.1 3.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4428 PF14471.6 CDS33201.2 - 4.3 7.3 11.2 15 5.6 2.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-piccolo PF05715.13 CDS33201.2 - 4.5 7.5 13.9 19 5.5 3.1 3.5 2 0 0 2 2 2 0 Piccolo Zn-finger PAC1 PF16094.5 CDS33202.2 - 2.5e-09 36.7 0.2 3.7e-08 32.9 0.1 2.0 1 1 0 2 2 2 1 Proteasome assembly chaperone 4 Vg_Tdu PF07545.14 CDS33202.2 - 0.14 11.9 0.3 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Vestigial/Tondu family Myotub-related PF06602.14 CDS33204.2 - 1.4e-69 234.7 0.0 2.4e-68 230.6 0.0 2.4 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain SBF2 PF12335.8 CDS33204.2 - 5.2e-29 101.5 0.7 2.2e-24 86.3 0.1 2.4 2 0 0 2 2 2 2 Myotubularin protein PH PF00169.29 CDS33204.2 - 1.7e-13 51.0 0.0 3.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 CDS33204.2 - 8e-07 28.8 6.6 1.5e-06 27.9 6.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH_11 PF15413.6 CDS33204.2 - 1.5e-05 25.3 0.0 5e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain GRAM PF02893.20 CDS33204.2 - 2.3e-05 24.2 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_8 PF15409.6 CDS33204.2 - 6.3e-05 23.2 0.1 0.0002 21.5 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 CDS33204.2 - 0.99 9.8 5.6 2.2 8.7 5.6 1.6 1 0 0 1 1 1 0 C1 domain TMIE PF16038.5 CDS33205.1 - 0.18 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 TMIE protein EF-hand_1 PF00036.32 CDS33206.2 - 3e-17 60.8 6.2 5.2e-07 28.8 0.7 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CDS33206.2 - 7.6e-16 58.3 0.6 9.1e-11 42.1 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS33206.2 - 1.8e-15 55.4 4.8 6.1e-05 22.6 0.2 4.0 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CDS33206.2 - 4.8e-12 44.8 3.3 5.3e-05 22.5 0.8 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CDS33206.2 - 1.4e-08 34.4 4.1 0.0037 17.1 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS33206.2 - 0.00022 21.5 0.1 0.00093 19.5 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CDS33206.2 - 0.00043 20.1 0.8 0.0013 18.5 0.1 2.2 2 1 1 3 3 3 1 EF hand EF-hand_4 PF12763.7 CDS33206.2 - 0.11 12.5 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Frizzled PF01534.17 CDS33207.1 - 1.9e-39 135.6 11.9 3.6e-39 134.7 11.9 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CDS33207.1 - 8.2e-28 97.2 2.7 1.4e-27 96.5 2.7 1.4 1 0 0 1 1 1 1 Fz domain Ax_dynein_light PF10211.9 CDS33208.1 - 1.1e-64 217.8 5.9 1.1e-64 217.8 5.9 1.3 2 0 0 2 2 2 1 Axonemal dynein light chain FH2 PF02181.23 CDS33208.1 - 0.0015 17.8 3.1 0.0015 17.7 1.8 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain TSNAXIP1_N PF15739.5 CDS33208.1 - 0.0072 16.7 4.3 0.059 13.8 0.5 2.5 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus ORF6C PF10552.9 CDS33208.1 - 0.014 15.5 1.5 0.035 14.2 1.5 1.6 1 0 0 1 1 1 0 ORF6C domain DUF1515 PF07439.11 CDS33208.1 - 0.073 13.1 2.4 0.28 11.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Syntaxin-6_N PF09177.11 CDS33208.1 - 1.1 9.8 7.4 0.34 11.5 1.6 2.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 CDS33208.1 - 1.6 8.8 5.8 0.5 10.4 0.7 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 CDS33208.1 - 2 8.3 8.2 4.1 7.3 1.5 3.3 2 1 1 3 3 3 0 Septum formation initiator Shugoshin_N PF07558.11 CDS33208.1 - 2.5 8.0 5.6 0.3 11.0 0.3 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HalX PF08663.10 CDS33208.1 - 3.6 8.0 9.2 13 6.2 0.1 3.3 3 0 0 3 3 3 0 HalX domain APG6_N PF17675.1 CDS33208.1 - 9.3 6.8 11.2 26 5.4 7.5 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region HMG_box PF00505.19 CDS33212.1 - 1.6e-13 50.8 0.1 5.8e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 CDS33212.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Myc_target_1 PF15179.6 CDS33213.1 - 0.0014 18.6 0.7 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 Myc target protein 1 DUF4834 PF16118.5 CDS33213.1 - 0.017 16.0 0.1 0.017 16.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Hid1 PF12722.7 CDS33213.1 - 0.049 11.8 12.5 0.062 11.4 12.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Comm PF15957.5 CDS33213.1 - 0.2 12.0 4.9 9 6.7 4.9 2.2 1 1 0 1 1 1 0 Commissureless DUF2681 PF10883.8 CDS33213.1 - 3.4 8.1 12.4 32 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 CDS33213.1 - 3.9 8.4 8.5 1.2e+02 3.6 8.5 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MMM1 PF10296.9 CDS33213.1 - 5.4 6.0 13.1 0.057 12.5 0.5 2.0 1 1 1 2 2 2 0 Maintenance of mitochondrial morphology protein 1 tRNA-synt_2c PF01411.19 CDS33215.1 - 3.5e-213 709.1 0.0 4.4e-213 708.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDS33215.1 - 5.3e-18 64.8 1.2 1.2e-17 63.7 1.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDS33215.1 - 3.7e-11 43.6 0.4 1.3e-10 41.8 0.4 2.0 1 0 0 1 1 1 1 DHHA1 domain Peptidase_S49 PF01343.18 CDS33215.1 - 0.04 13.9 0.1 5.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Peptidase family S49 Ndufs5 PF10200.9 CDS33216.1 - 1.4e-08 34.9 0.1 1.9e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UCR_hinge PF02320.16 CDS33216.1 - 0.12 12.5 0.7 0.12 12.5 0.7 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF4588 PF15251.6 CDS33217.1 - 0.039 13.7 1.2 0.094 12.5 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Ribonuc_red_sm PF00268.21 CDS33218.1 - 1.1e-120 402.3 0.1 1.3e-120 402.1 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Pkinase_Tyr PF07714.17 CDS33219.1 - 2e-52 178.1 0.0 5e-52 176.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CDS33219.1 - 1.3e-47 162.4 0.0 2.1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 CDS33219.1 - 8.7e-09 35.1 0.0 2.5e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDS33219.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS33219.1 - 3.4e-05 23.3 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain APH PF01636.23 CDS33219.1 - 0.0016 18.4 0.5 0.78 9.6 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDS33219.1 - 0.017 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CDS33219.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TGS PF02824.21 CDS33220.1 - 8.3e-05 22.6 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain Pellino PF04710.14 CDS33221.1 - 2.4e-129 431.7 0.0 1.4e-128 429.1 0.0 1.9 1 1 0 1 1 1 1 Pellino zf-RING_2 PF13639.6 CDS33221.1 - 0.085 13.2 5.7 2 8.8 0.3 2.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 CDS33221.1 - 0.39 10.6 8.0 8.6 6.3 2.2 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ldl_recept_a PF00057.18 CDS33222.1 - 1.4e-204 661.9 506.9 3.9e-10 39.8 9.1 31.9 31 0 0 31 31 31 31 Low-density lipoprotein receptor domain class A Ig_2 PF13895.6 CDS33222.1 - 2.3e-49 165.6 8.2 1.2e-08 35.2 0.0 16.6 19 0 0 19 19 17 7 Immunoglobulin domain Ig_3 PF13927.6 CDS33222.1 - 4e-47 158.7 29.0 3.7e-10 40.3 0.0 19.2 22 0 0 22 22 22 7 Immunoglobulin domain I-set PF07679.16 CDS33222.1 - 1.4e-28 98.7 0.0 3.7e-07 30.1 0.0 13.6 16 0 0 16 16 16 3 Immunoglobulin I-set domain ig PF00047.25 CDS33222.1 - 4.3e-18 65.3 0.2 0.019 15.1 0.0 9.1 9 1 0 9 9 9 4 Immunoglobulin domain V-set PF07686.17 CDS33222.1 - 4.1e-10 39.8 2.9 2.1 8.5 0.0 8.1 7 1 0 7 7 7 3 Immunoglobulin V-set domain Ig_6 PF18452.1 CDS33222.1 - 5.1e-05 22.8 1.8 0.3 10.7 0.0 4.5 5 0 0 5 5 5 1 Immunoglobulin domain PKD PF00801.20 CDS33222.1 - 0.00033 20.4 0.5 0.47 10.3 0.0 4.1 4 0 0 4 4 4 1 PKD domain CIDE-N PF02017.15 CDS33222.1 - 0.015 15.3 0.0 42 4.3 0.0 4.5 4 0 0 4 4 4 0 CIDE-N domain C2-set PF05790.15 CDS33222.1 - 0.017 15.3 0.0 28 5.0 0.0 3.8 4 0 0 4 4 3 0 Immunoglobulin C2-set domain Lep_receptor_Ig PF06328.11 CDS33222.1 - 0.022 14.7 0.7 2.1 8.4 0.0 4.7 5 0 0 5 5 5 0 Ig-like C2-type domain C2 PF00168.30 CDS33223.1 - 4.1e-63 210.1 0.2 7.3e-17 61.5 0.0 7.6 7 1 0 7 7 7 6 C2 domain FerB PF08150.12 CDS33223.1 - 2.6e-24 85.6 0.0 7.6e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 FerB (NUC096) domain Ferlin_C PF16165.5 CDS33223.1 - 3.7e-24 85.4 10.5 1e-21 77.5 0.1 3.4 2 1 1 3 3 3 2 Ferlin C-terminus FerI PF08151.12 CDS33223.1 - 1.8e-05 24.7 0.4 1.8e-05 24.7 0.4 2.0 2 0 0 2 2 2 1 FerI (NUC094) domain dsRBD2 PF17842.1 CDS33223.1 - 0.039 14.1 0.7 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 DUF1281_C PF18406.1 CDS33224.1 - 0.095 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein tRNA-synt_1 PF00133.22 CDS33225.2 - 7.1e-141 470.4 0.0 6.4e-140 467.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Glyco_hydro_85 PF03644.13 CDS33225.2 - 3.8e-78 263.0 0.0 6.2e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Anticodon_1 PF08264.13 CDS33225.2 - 1.9e-18 66.8 0.0 4.8e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Ribosomal_L17 PF01196.19 CDS33225.2 - 6.7e-09 36.5 0.0 1.4e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 tRNA-synt_1g PF09334.11 CDS33225.2 - 4.9e-07 28.8 0.0 0.033 12.9 0.0 3.7 4 0 0 4 4 4 3 tRNA synthetases class I (M) TFIIS_C PF01096.18 CDS33225.2 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Rhomboid PF01694.22 CDS33226.1 - 4.3e-23 82.0 12.5 4.3e-23 82.0 12.5 1.6 2 0 0 2 2 2 1 Rhomboid family Band_7 PF01145.25 CDS33227.1 - 4.8e-20 72.3 2.6 4.8e-20 72.3 2.6 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.8 CDS33227.1 - 0.0025 17.9 1.6 0.0044 17.1 1.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 TTc_toxin_rep PF18807.1 CDS33227.1 - 0.068 13.0 0.2 0.068 13.0 0.2 1.8 2 0 0 2 2 2 0 Tripartite Tc toxins repeat DUF4483 PF14825.6 CDS33228.1 - 2.1e-29 102.3 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) APC_u14 PF16635.5 CDS33228.1 - 0.13 12.8 1.0 0.36 11.4 1.0 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr NRDE-2 PF08424.10 CDS33229.1 - 1.5e-91 306.9 0.2 7.3e-91 304.6 0.0 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference ETC_C1_NDUFA5 PF04716.14 CDS33230.1 - 0.0062 16.3 0.0 5.9 6.8 0.0 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region EB1 PF03271.17 CDS33231.1 - 0.044 14.0 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 EB1-like C-terminal motif zf-U11-48K PF05253.12 CDS33232.1 - 0.0018 18.1 1.4 0.0038 17.1 1.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger IRS PF02174.17 CDS33233.1 - 3.3e-13 49.4 0.0 5.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) CDP-OH_P_transf PF01066.21 CDS33234.1 - 9e-12 45.6 0.8 9e-12 45.6 0.8 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase IMS PF00817.20 CDS33235.1 - 4.7e-35 120.8 0.0 1.1e-34 119.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDS33235.1 - 1.2e-13 51.8 0.0 3.7e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 CDS33235.1 - 7e-12 45.6 0.0 1.8e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 CDS33235.1 - 7.5e-11 42.3 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDS33235.1 - 1e-07 32.2 0.0 2.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 CDS33235.1 - 5.8e-05 23.6 0.0 0.00055 20.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 CDS33235.1 - 0.00052 20.2 0.0 0.05 13.9 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 CDS33235.1 - 0.012 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CDS33235.1 - 0.048 13.6 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain DUF4251 PF14059.6 CDS33236.1 - 0.11 12.5 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) Hormone_recep PF00104.30 CDS33238.1 - 0.00048 19.8 1.6 0.015 14.8 0.0 2.5 2 0 0 2 2 2 2 Ligand-binding domain of nuclear hormone receptor gag-asp_proteas PF13975.6 CDS33240.1 - 0.011 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 CDS33240.1 - 0.022 15.0 3.2 0.054 13.8 0.0 3.0 3 0 0 3 3 3 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDS33240.1 - 0.1 13.3 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Spt20 PF12090.8 CDS33240.1 - 9 5.8 22.1 0.73 9.4 12.0 2.4 2 0 0 2 2 2 0 Spt20 family DASH_Duo1 PF08651.10 CDS33244.1 - 0.001 18.8 8.7 0.72 9.7 0.2 4.3 2 2 2 4 4 4 2 DASH complex subunit Duo1 Syntaxin-6_N PF09177.11 CDS33244.1 - 0.014 16.0 2.5 0.42 11.2 0.9 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SPATA1_C PF15743.5 CDS33244.1 - 0.018 15.1 0.4 0.039 14.0 0.4 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Spc7 PF08317.11 CDS33244.1 - 0.024 13.5 1.4 0.8 8.5 0.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Peptidase_S46 PF10459.9 CDS33244.1 - 0.026 13.2 0.3 0.036 12.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase S46 ZapB PF06005.12 CDS33244.1 - 0.11 12.9 5.2 2.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 CDS33244.1 - 0.14 11.4 1.3 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 CDS33244.1 - 2.1 7.8 4.7 3.8 7.0 4.7 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit RNase_H PF00075.24 CDS33247.1 - 1.4e-07 31.8 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNase H RRM_1 PF00076.22 CDS33248.1 - 3e-18 65.4 0.2 4.2e-13 48.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS33248.1 - 0.074 12.6 0.0 0.41 10.2 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1_POZ PF03931.15 CDS33249.1 - 7.1e-05 22.9 0.1 0.00013 22.1 0.1 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain RRM_1 PF00076.22 CDS33250.1 - 1e-18 66.9 0.0 5.9e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS33250.1 - 0.00098 18.7 0.0 0.0029 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 CDS33251.1 - 2.8e-40 138.0 0.5 7.2e-40 136.6 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS33251.1 - 1.7e-28 99.2 0.0 8.5e-28 96.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS33251.1 - 6.8e-08 32.7 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDS33251.1 - 5.8e-06 26.7 0.4 0.00014 22.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDS33251.1 - 1.6e-05 24.7 0.4 4.2e-05 23.3 0.1 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 CDS33251.1 - 0.00021 20.7 0.0 0.00021 20.7 0.0 2.8 2 1 0 2 2 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CDS33251.1 - 0.0018 17.2 0.0 0.55 8.9 0.0 3.0 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 CDS33251.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Helicase NACHT PF05729.12 CDS33251.1 - 0.026 14.5 0.2 0.073 13.0 0.1 1.8 2 0 0 2 2 2 0 NACHT domain DAGK_cat PF00781.24 CDS33251.1 - 0.027 14.1 0.4 0.077 12.6 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain AAA_22 PF13401.6 CDS33251.1 - 0.038 14.3 1.2 0.22 11.8 1.2 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 CDS33251.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 CDS33251.1 - 0.12 11.8 0.3 0.41 10.1 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein Thioredoxin PF00085.20 CDS33252.1 - 6.5e-13 48.6 0.1 8.1e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDS33252.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CDS33252.1 - 0.014 15.9 0.1 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 CDS33252.1 - 0.033 14.4 0.5 0.07 13.4 0.2 1.8 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.6 CDS33252.1 - 0.043 14.2 0.0 0.07 13.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 CDS33252.1 - 0.07 13.0 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin PF00085.20 CDS33253.1 - 3.2e-12 46.3 0.1 4.5e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CDS33253.1 - 7.8e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CDS33253.1 - 2.8e-05 24.2 0.5 4.8e-05 23.5 0.2 1.5 2 0 0 2 2 2 1 Thioredoxin-like DIM1 PF02966.16 CDS33253.1 - 4.7e-05 23.2 0.2 6.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 CDS33253.1 - 0.00022 21.6 0.1 0.0011 19.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 CDS33253.1 - 0.0004 20.5 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CDS33253.1 - 0.0053 17.1 0.2 0.014 15.8 0.0 1.9 2 1 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 CDS33253.1 - 0.027 14.8 0.1 0.049 14.0 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 CDS33253.1 - 0.083 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glyco_transf_43 PF03360.16 CDS33254.2 - 3.6e-53 180.5 0.0 4.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glycos_transf_2 PF00535.26 CDS33254.2 - 0.021 14.7 0.0 0.03 14.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 Pkinase_Tyr PF07714.17 CDS33255.1 - 8.5e-82 274.3 0.0 5.2e-81 271.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS33255.1 - 4.9e-41 140.8 0.0 1e-40 139.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS33255.1 - 2.5e-06 27.5 0.0 0.00029 20.9 0.0 3.1 3 0 0 3 3 3 1 SH2 domain DUF885 PF05960.11 CDS33255.1 - 0.022 14.4 0.3 0.035 13.7 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Baculo_PEP_C PF04513.12 CDS33255.1 - 0.075 13.1 0.3 0.2 11.7 0.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RIO1 PF01163.22 CDS33255.1 - 0.19 11.3 0.0 0.75 9.4 0.0 1.9 1 1 1 2 2 2 0 RIO1 family TMEM154 PF15102.6 CDS33257.1 - 0.093 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family PXA PF02194.15 CDS33258.1 - 2.6e-22 79.7 2.9 1.9e-15 57.3 0.6 2.9 2 0 0 2 2 2 2 PXA domain PX PF00787.24 CDS33258.1 - 4.6e-09 36.3 0.3 2.1e-08 34.1 0.3 2.2 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 CDS33258.1 - 0.024 15.2 0.0 0.068 13.8 0.0 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal Dynactin_p22 PF07426.11 CDS33258.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 MOZ_SAS PF01853.18 CDS33259.1 - 5.9e-72 241.1 0.1 1.2e-71 240.1 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDS33259.1 - 8.9e-20 70.1 6.2 2.7e-19 68.5 6.2 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 CDS33259.1 - 1.9e-14 53.3 18.4 3.5e-10 39.6 4.1 3.0 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 CDS33259.1 - 0.066 13.3 18.1 0.3 11.2 8.2 2.8 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 CDS33259.1 - 0.2 11.6 20.0 0.075 13.0 1.1 3.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 CDS33259.1 - 0.62 10.6 6.5 0.092 13.2 0.6 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type PHD_2 PF13831.6 CDS33259.1 - 3.7 7.2 16.9 0.16 11.5 0.9 3.0 2 1 0 2 2 2 0 PHD-finger zf-C2H2_jaz PF12171.8 CDS33259.1 - 6.1 7.3 9.3 0.091 13.1 0.7 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Romo1 PF10247.9 CDS33261.2 - 2.6 8.5 9.1 2.9 8.3 0.9 2.6 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 HTH_34 PF13601.6 CDS33263.1 - 0.052 13.7 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF3087 PF11286.8 CDS33263.1 - 0.078 12.4 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Dicty_REP PF05086.12 CDS33266.1 - 2.2 6.1 4.5 2.8 5.8 4.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.12 CDS33266.1 - 4.2 5.5 5.0 4.7 5.3 5.0 1.0 1 0 0 1 1 1 0 Nop14-like family PRIMA1 PF16101.5 CDS33269.2 - 0.32 11.0 5.6 0.44 10.6 5.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CDS33269.2 - 0.55 9.7 4.1 0.61 9.5 4.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 4HB_MCP_1 PF12729.7 CDS33270.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Parvo_NS1 PF01057.17 CDS33272.1 - 2.5e-05 23.5 0.1 2.8e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Ku_N PF03731.15 CDS33272.1 - 0.051 13.3 0.1 0.061 13.1 0.1 1.2 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain VWA_N PF08399.11 CDS33273.1 - 0.085 13.3 1.2 0.11 13.0 1.2 1.1 1 0 0 1 1 1 0 VWA N-terminal S6OS1 PF15676.5 CDS33273.1 - 0.13 10.7 2.2 0.13 10.8 2.2 1.0 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Skp1 PF01466.19 CDS33276.1 - 2.7e-05 24.2 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDS33276.1 - 0.027 14.6 0.7 0.082 13.1 0.7 1.8 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain MCM PF00493.23 CDS33277.1 - 2.7e-97 324.3 0.0 4.1e-97 323.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS33277.1 - 1.3e-35 122.0 0.4 2.7e-35 121.0 0.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS33277.1 - 2.6e-26 91.8 2.1 5.5e-26 90.8 2.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDS33277.1 - 2.6e-16 60.1 0.0 8.3e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDS33277.1 - 1.8e-06 27.5 0.0 2.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS33277.1 - 7.9e-05 22.7 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDS33277.1 - 0.016 14.9 0.0 0.12 12.0 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDS33277.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 CDS33277.1 - 0.77 9.9 2.5 1.9 8.6 2.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_S14 PF00253.21 CDS33278.1 - 2.8e-12 46.2 6.4 3.6e-12 45.8 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ETX_MTX2 PF03318.13 CDS33280.1 - 6.4e-06 26.1 1.7 1e-05 25.5 1.7 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF772 PF05598.11 CDS33282.2 - 0.18 11.9 0.5 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Transposase domain (DUF772) DUF772 PF05598.11 CDS33283.1 - 0.11 12.5 0.6 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Transposase domain (DUF772) NGP1NT PF08153.12 CDS33285.1 - 1e-38 132.4 1.2 2.2e-38 131.3 1.2 1.6 1 1 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CDS33285.1 - 6.7e-18 64.8 0.0 1.3e-13 51.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDS33285.1 - 8.5e-06 25.9 2.5 0.26 11.3 0.0 4.0 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 CDS33285.1 - 1.1e-05 25.0 0.2 2.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDS33285.1 - 5e-05 22.9 0.1 0.0091 15.5 0.0 3.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDS33285.1 - 0.00022 21.2 0.0 0.00072 19.5 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CDS33285.1 - 0.00083 18.8 0.1 1.1 8.7 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDS33285.1 - 0.03 14.5 0.1 5.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CDS33285.1 - 0.075 13.6 0.0 0.25 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 CDS33285.1 - 0.16 11.0 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TMA7 PF09072.10 CDS33286.1 - 2e-17 63.8 17.5 2.4e-17 63.5 17.5 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 ATP-synt_E PF05680.12 CDS33286.1 - 0.024 15.0 3.8 0.03 14.7 3.8 1.1 1 0 0 1 1 1 0 ATP synthase E chain Oxidored_nitro PF00148.19 CDS33286.1 - 0.036 12.8 0.0 0.046 12.4 0.0 1.0 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Glyco_transf_43 PF03360.16 CDS33288.1 - 1.8e-56 191.2 0.0 2.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glycos_transf_2 PF00535.26 CDS33288.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Guanylate_kin PF00625.21 CDS33289.1 - 2.7e-62 209.7 0.0 3e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CDS33289.1 - 1.4e-05 25.3 0.0 3.3e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDS33289.1 - 4.4e-05 24.0 0.0 0.00043 20.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CDS33289.1 - 6.5e-05 23.4 0.1 0.00013 22.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CDS33289.1 - 6.9e-05 23.4 0.0 0.00012 22.6 0.0 1.5 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 CDS33289.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDS33289.1 - 0.00028 20.8 0.0 0.00076 19.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDS33289.1 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 CDS33289.1 - 0.0019 18.0 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 CDS33289.1 - 0.0044 16.7 0.1 0.013 15.2 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 CDS33289.1 - 0.0045 16.6 0.0 0.057 13.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 CDS33289.1 - 0.0075 16.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 CDS33289.1 - 0.0077 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CDS33289.1 - 0.0082 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Thymidylate_kin PF02223.17 CDS33289.1 - 0.0089 15.7 0.0 0.096 12.4 0.0 2.0 1 1 1 2 2 2 1 Thymidylate kinase T2SSE PF00437.20 CDS33289.1 - 0.015 14.3 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 CDS33289.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CDS33289.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 CDS33289.1 - 0.023 15.1 0.2 0.06 13.8 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDS33289.1 - 0.035 14.1 0.1 0.34 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CDS33289.1 - 0.053 13.4 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CDS33289.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CDS33289.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDS33289.1 - 0.06 13.1 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS33289.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CDS33289.1 - 0.12 12.1 0.1 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_21 PF13304.6 CDS33289.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 CDS33289.1 - 0.13 12.1 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 CDS33289.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 CDS33289.1 - 0.2 12.1 2.1 0.57 10.6 2.1 2.0 1 1 0 1 1 1 0 AAA domain Fanconi_A_N PF15865.5 CDS33291.1 - 1.4e-09 37.8 0.0 4.2e-05 23.1 0.0 2.5 2 1 0 2 2 2 2 Fanconi anaemia group A protein N terminus CAP_N PF01213.19 CDS33292.2 - 0.83 9.1 2.3 1.1 8.7 2.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NTF2 PF02136.20 CDS33293.1 - 2e-21 76.8 0.0 3.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Tautomerase_2 PF14552.6 CDS33295.1 - 0.037 14.1 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme Peptidase_S10 PF00450.22 CDS33297.1 - 3.1e-120 402.4 0.3 3.6e-120 402.2 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 CDS33297.1 - 0.033 14.8 0.0 0.3 11.6 0.0 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family LPAM_1 PF08139.12 CDS33297.1 - 0.36 11.4 2.8 0.69 10.5 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site HLH PF00010.26 CDS33298.1 - 0.0057 16.6 0.3 0.0074 16.2 0.3 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF679 PF05078.12 CDS33298.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF679) HLH PF00010.26 CDS33299.1 - 0.084 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Integrase_H2C2 PF17921.1 CDS33302.1 - 8.1e-16 57.9 1.8 1.4e-15 57.1 1.8 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS33302.1 - 0.018 15.2 0.2 0.028 14.6 0.2 1.3 1 0 0 1 1 1 0 H2C2 zinc finger TF_AP-2 PF03299.14 CDS33303.2 - 1.6e-74 250.2 0.0 2.3e-73 246.4 0.0 2.8 3 0 0 3 3 3 1 Transcription factor AP-2 DUF4483 PF14825.6 CDS33303.2 - 0.00061 19.6 6.2 0.14 12.0 0.8 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4483) DUF5093 PF17011.5 CDS33303.2 - 0.0089 16.3 0.0 7.1 6.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5093) MethyTransf_Reg PF10119.9 CDS33303.2 - 0.0096 16.6 0.5 12 6.7 0.1 2.9 2 0 0 2 2 2 2 Predicted methyltransferase regulatory domain FIN1 PF17300.2 CDS33303.2 - 0.017 14.7 2.1 0.066 12.7 0.2 2.3 2 0 0 2 2 2 0 Filaments in between nuclei protein-1 HTH_IclR PF09339.10 CDS33303.2 - 0.017 14.9 0.2 11 5.9 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Glyco_transf_21 PF13506.6 CDS33303.2 - 0.023 14.2 0.1 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 PRF PF06875.11 CDS33303.2 - 0.06 12.8 0.1 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF Sif PF06767.11 CDS33303.2 - 0.17 10.9 0.0 18 4.2 0.0 2.2 2 0 0 2 2 2 0 Sif protein Arc PF03869.14 CDS33303.2 - 0.17 11.8 0.5 31 4.5 0.1 2.6 2 0 0 2 2 2 0 Arc-like DNA binding domain 7tm_1 PF00001.21 CDS33304.1 - 7.5e-20 71.4 6.8 7.5e-20 71.4 6.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS33304.1 - 7.9e-12 45.3 7.1 7.9e-12 45.3 7.1 2.3 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.9 CDS33304.1 - 2.5e-08 33.6 6.2 2.5e-08 33.6 6.2 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Cas9_REC PF16592.5 CDS33306.1 - 0.072 11.8 0.1 0.072 11.8 0.1 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 RA PF00788.23 CDS33306.1 - 0.11 13.1 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Cation_ATPase_N PF00690.26 CDS33306.1 - 0.15 11.8 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus CLPTM1 PF05602.12 CDS33309.1 - 2.1e-142 475.1 5.3 2.8e-142 474.7 5.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CDS33309.1 - 0.014 15.1 3.3 0.065 13.0 0.4 2.7 2 0 0 2 2 2 0 PQ loop repeat Ran_BP1 PF00638.18 CDS33310.1 - 6.8e-08 32.8 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain MTBP_N PF14918.6 CDS33310.1 - 9.4 5.6 7.9 0.31 10.5 1.5 1.7 2 0 0 2 2 2 0 MDM2-binding Cyclin_N PF00134.23 CDS33311.1 - 4.2e-24 84.7 1.3 1.1e-23 83.3 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CDS33311.1 - 0.00014 21.8 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 CDS33311.1 - 0.0016 18.5 1.4 0.11 12.6 0.1 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB_C_1 PF18542.1 CDS33311.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 rRNA_proc-arch PF13234.6 CDS33312.1 - 7.5e-56 190.0 0.4 1.4e-55 189.1 0.4 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CDS33312.1 - 5e-47 159.6 0.0 8.5e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDS33312.1 - 5.3e-16 58.9 0.0 1.3e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS33312.1 - 5.2e-07 29.8 1.1 9.4e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDS33312.1 - 7.2e-05 23.1 0.0 0.00026 21.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDS33312.1 - 0.074 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDS33312.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CDS33312.1 - 0.12 11.4 0.0 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein KH_6 PF15985.5 CDS33313.1 - 8.6e-14 51.6 0.1 4.7e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 KH domain Peptidase_S28 PF05577.12 CDS33314.1 - 1.3e-85 287.8 0.0 1.5e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 CDS33314.1 - 0.00023 20.9 0.0 0.00091 18.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS33314.1 - 0.00027 20.3 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 CDS33314.1 - 0.00033 19.5 0.0 0.00049 18.9 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 CDS33314.1 - 0.0042 16.6 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDS33314.1 - 0.018 15.6 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.8 CDS33314.1 - 0.032 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Esterase PF00756.20 CDS33314.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PID PF00640.23 CDS33317.1 - 3.9e-17 62.6 1.7 3.9e-15 56.1 0.4 2.5 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) DTHCT PF08070.11 CDS33317.1 - 1.4 9.7 18.1 0.86 10.4 4.3 2.6 1 1 1 2 2 2 0 DTHCT (NUC029) region P21-Arc PF04062.14 CDS33318.1 - 1.5e-70 236.8 0.1 1.6e-70 236.6 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SUI1 PF01253.22 CDS33319.1 - 2.3e-17 63.3 0.1 3.5e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 HasA PF06438.12 CDS33319.1 - 0.048 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) DUF2497 PF10691.9 CDS33319.1 - 0.17 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) TRIQK PF15168.6 CDS33320.1 - 1.5e-07 31.2 0.1 1.8e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family CENP-F_leu_zip PF10473.9 CDS33321.1 - 0.0054 16.8 2.6 0.01 15.8 2.6 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-ATPase_G PF03179.15 CDS33322.1 - 4e-24 85.2 9.7 4.6e-24 85.0 9.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RNA_pol_Rpb8 PF03870.15 CDS33322.1 - 0.042 14.0 0.8 0.086 13.0 0.2 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb8 OMS28_porin PF03532.13 CDS33322.1 - 0.074 12.3 2.3 0.087 12.0 2.3 1.1 1 0 0 1 1 1 0 OMS28 porin Pkinase PF00069.25 CDS33323.1 - 1.5e-64 217.9 0.0 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33323.1 - 4.7e-34 117.8 0.0 6.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDS33323.1 - 2.5e-15 56.1 3.4 5.6e-15 55.0 3.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 CDS33323.1 - 2.5e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PB1 PF00564.24 CDS33323.1 - 0.00032 20.6 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.24 CDS33323.1 - 0.00048 20.8 2.4 0.0013 19.4 2.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 CDS33323.1 - 0.00062 20.0 2.1 0.0015 18.8 2.1 1.7 1 0 0 1 1 1 1 C1 domain Haspin_kinase PF12330.8 CDS33323.1 - 0.016 14.2 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Orthopox_F8 PF05886.11 CDS33323.1 - 0.2 11.8 1.2 0.89 9.7 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Glyco_transf_22 PF03901.17 CDS33326.1 - 1.3e-58 199.2 35.6 1.6e-58 198.9 35.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HTH_46 PF15977.5 CDS33327.1 - 0.062 13.3 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding MAP17 PF15807.5 CDS33330.1 - 5.6 7.2 6.6 0.8 9.9 2.1 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PDZ PF00595.24 CDS33331.1 - 8.5e-12 45.3 0.3 4.8e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDS33331.1 - 2.2e-11 43.4 0.0 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDS33331.1 - 1.7e-06 28.2 0.0 6.6e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 PDZ domain NMT1_3 PF16868.5 CDS33331.1 - 0.019 14.4 0.1 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 NMT1-like family DUF3394 PF11874.8 CDS33331.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) RabGAP-TBC PF00566.18 CDS33332.1 - 2.1e-43 148.5 2.7 3.2e-43 147.9 2.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PLAC8 PF04749.17 CDS33333.1 - 6.8e-08 33.4 12.0 8.8e-08 33.1 12.0 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2784 PF10861.8 CDS33333.1 - 0.11 12.6 1.8 0.16 12.0 1.8 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) RCC1 PF00415.18 CDS33334.1 - 6.4e-63 209.2 6.4 4.9e-12 46.3 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDS33334.1 - 1.5e-21 75.7 35.6 0.00011 21.9 0.8 8.3 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Lambda_CIII PF02061.16 CDS33334.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.0 1 0 0 1 1 1 0 Lambda Phage CIII G-gamma PF00631.22 CDS33335.1 - 6.4e-07 29.3 0.2 8.7e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 GGL domain EF-hand_1 PF00036.32 CDS33336.1 - 5.4e-30 100.7 10.8 3.4e-07 29.4 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS33336.1 - 9.7e-27 93.2 3.0 8.9e-15 54.9 0.4 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS33336.1 - 1.6e-24 83.6 4.9 1.9e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS33336.1 - 1.9e-21 74.5 11.0 1.6e-05 24.2 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS33336.1 - 5e-17 61.5 9.2 6.7e-05 22.7 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDS33336.1 - 1.6e-08 34.8 0.1 0.0012 19.1 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDS33336.1 - 2.3e-08 33.9 3.4 0.0026 17.7 0.6 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDS33336.1 - 4.7e-05 23.6 0.2 0.023 15.0 0.0 3.0 2 2 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 CDS33336.1 - 0.0054 16.7 3.6 15 5.5 0.1 3.8 1 1 3 4 4 4 2 Caleosin related protein Dockerin_1 PF00404.18 CDS33336.1 - 0.015 15.5 3.2 0.23 11.7 0.8 3.3 2 1 2 4 4 4 0 Dockerin type I domain DUF1908 PF08926.11 CDS33338.1 - 2e-79 266.7 0.0 2e-79 266.7 0.0 3.4 3 2 0 3 3 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.25 CDS33338.1 - 2.9e-59 200.6 0.0 4.6e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33338.1 - 3.1e-26 92.2 0.0 7.5e-26 91.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 CDS33338.1 - 4.6e-09 36.0 0.1 9e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CDS33338.1 - 5.8e-09 36.2 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain APH PF01636.23 CDS33338.1 - 3.4e-05 23.9 0.0 0.022 14.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family PDZ_2 PF13180.6 CDS33338.1 - 0.00017 21.9 0.1 0.00062 20.0 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Kinase-like PF14531.6 CDS33338.1 - 0.0019 17.6 0.0 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDS33338.1 - 0.0047 15.9 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain MHCassoc_trimer PF08831.10 CDS33338.1 - 0.028 14.4 0.1 0.055 13.5 0.1 1.5 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Pkinase_fungal PF17667.1 CDS33338.1 - 0.59 8.9 1.8 0.73 8.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase zf-RING_UBOX PF13445.6 CDS33339.1 - 5.5e-05 23.1 0.6 5.5e-05 23.1 0.6 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDS33339.1 - 5.9e-05 23.1 1.8 9.4e-05 22.5 0.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CDS33339.1 - 0.00024 20.9 0.6 0.00066 19.5 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS33339.1 - 0.00078 19.3 0.3 0.0024 17.7 0.0 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS33339.1 - 0.037 13.9 4.3 0.046 13.6 1.6 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CDS33339.1 - 0.068 13.5 0.2 0.068 13.5 0.2 2.3 2 2 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 CDS33339.1 - 0.5 10.4 3.0 0.57 10.2 0.6 2.3 2 1 1 3 3 3 0 zinc-RING finger domain HTH_48 PF17906.1 CDS33340.1 - 2.4e-09 37.1 0.7 5.6e-09 36.0 0.7 1.6 1 1 0 1 1 1 1 HTH domain in Mos1 transposase CopK PF11525.8 CDS33340.1 - 0.049 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Copper resistance protein K Syndecan PF01034.20 CDS33341.2 - 2.7e-26 91.3 0.0 5.3e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 CDS33341.2 - 0.00016 21.9 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A Lambda_CIII PF02061.16 CDS33341.2 - 0.02 15.0 4.6 4.9 7.3 0.0 3.5 4 0 0 4 4 4 0 Lambda Phage CIII TMEM213 PF15192.6 CDS33341.2 - 0.042 13.8 0.4 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 TMEM213 family Gram_pos_anchor PF00746.21 CDS33341.2 - 0.27 11.2 0.2 0.54 10.3 0.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Peptidase_C1 PF00112.23 CDS33343.1 - 1.6e-60 204.9 0.1 2.3e-60 204.4 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CDS33343.1 - 1.5e-09 38.1 6.6 3.4e-09 37.0 6.6 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CDS33343.1 - 0.00092 18.1 2.0 0.007 15.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase C1-like family S1 PF00575.23 CDS33344.1 - 0.031 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain TMEMspv1-c74-12 PF11044.8 CDS33344.1 - 0.66 10.0 5.9 3.8 7.6 0.2 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Lig_chan PF00060.26 CDS33345.1 - 7.4e-05 22.6 0.3 0.00017 21.5 0.3 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CDS33345.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 S1 PF00575.23 CDS33345.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain CDT1 PF08839.11 CDS33346.1 - 3.8e-49 167.4 2.1 1.5e-48 165.4 0.0 2.4 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 CDS33346.1 - 9.2e-13 48.4 2.4 2.2e-12 47.2 0.0 2.8 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain HEAT_EZ PF13513.6 CDS33347.1 - 2.9e-25 88.3 35.5 1.4e-08 35.1 0.2 16.9 18 1 1 19 19 18 5 HEAT-like repeat HEAT_2 PF13646.6 CDS33347.1 - 1.1e-22 80.2 18.1 1e-06 29.0 0.3 12.1 10 3 5 15 15 15 4 HEAT repeats HEAT PF02985.22 CDS33347.1 - 1.3e-22 78.0 45.3 0.003 17.7 0.0 20.4 23 0 0 23 23 21 5 HEAT repeat Vac14_Fab1_bd PF12755.7 CDS33347.1 - 4.3e-15 56.1 0.0 0.36 11.5 0.0 9.8 8 1 2 10 10 10 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDS33347.1 - 7.2e-13 48.9 2.4 0.13 12.3 0.0 9.3 8 1 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDS33347.1 - 3.8e-11 43.0 0.0 0.00046 19.8 0.0 6.2 6 1 1 7 7 7 3 CLASP N terminal Tti2 PF10521.9 CDS33347.1 - 3.6e-06 26.7 0.6 0.00021 21.0 0.0 4.3 4 1 0 5 5 5 1 Tti2 family UME PF08064.13 CDS33347.1 - 0.00016 21.5 0.2 7.4 6.5 0.0 6.4 5 2 0 5 5 5 1 UME (NUC010) domain TAF6_C PF07571.13 CDS33347.1 - 0.00016 21.9 0.8 6.3 7.2 0.0 5.5 6 0 0 6 6 5 1 TAF6 C-terminal HEAT repeat domain DUF3385 PF11865.8 CDS33347.1 - 0.0011 18.9 0.1 3.2 7.6 0.0 5.9 6 1 0 6 6 5 1 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 CDS33347.1 - 0.023 15.0 1.0 83 3.6 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.12 CDS33347.1 - 0.82 9.4 7.0 0.86 9.3 0.0 4.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HLH PF00010.26 CDS33349.1 - 1.2e-09 38.0 0.5 1.2e-09 38.0 0.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4653 PF15546.6 CDS33349.1 - 0.00046 19.9 0.1 0.0015 18.2 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4653) GATA PF00320.27 CDS33351.1 - 1.2e-16 59.9 12.8 1.3e-14 53.5 3.4 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CDS33351.1 - 0.0089 15.5 0.3 0.0089 15.5 0.3 2.7 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.7 CDS33351.1 - 0.35 10.9 16.8 30 4.7 8.4 3.4 1 1 1 2 2 2 0 Double zinc ribbon DUF4428 PF14471.6 CDS33351.1 - 1.5 8.8 9.2 1.5 8.8 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) Ig_3 PF13927.6 CDS33352.2 - 4.9e-32 110.4 5.3 0.0029 18.1 0.0 9.4 7 2 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 CDS33352.2 - 6.6e-21 74.3 10.8 0.00023 21.3 0.0 8.5 6 4 0 6 6 6 6 Immunoglobulin domain I-set PF07679.16 CDS33352.2 - 5.2e-20 71.3 0.7 0.047 13.8 0.0 7.8 6 2 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS33352.2 - 1.4e-14 54.2 0.8 0.094 13.1 0.0 9.0 9 0 0 9 9 9 2 Immunoglobulin domain C2-set_2 PF08205.12 CDS33352.2 - 1.4e-11 44.3 1.0 0.0015 18.5 0.0 5.9 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CDS33352.2 - 4.4e-11 42.9 6.3 0.09 13.0 0.0 7.7 6 2 0 6 6 6 2 Immunoglobulin V-set domain Ig_4 PF16680.5 CDS33352.2 - 7.9e-08 32.5 2.0 6.2 7.2 0.0 5.9 6 0 0 6 6 6 2 T-cell surface glycoprotein CD3 delta chain Marek_A PF02124.15 CDS33352.2 - 1.5 8.6 4.4 51 3.6 0.0 3.7 4 0 0 4 4 4 0 Marek's disease glycoprotein A Shisa PF13908.6 CDS33352.2 - 1.7 8.9 4.1 0.79 9.9 0.0 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Dynein_light PF01221.18 CDS33353.1 - 1e-13 51.4 0.0 2.9e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Dynein light chain type 1 Filo_VP35 PF02097.15 CDS33353.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 CBF PF03914.17 CDS33354.1 - 7.7e-38 130.2 0.0 7.7e-38 130.2 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 CDS33354.1 - 0.0036 15.9 0.2 0.049 12.2 0.0 2.1 1 1 0 2 2 2 1 Adaptin N terminal region Abhydrolase_3 PF07859.13 CDS33355.2 - 3.9e-18 66.1 0.0 1.3e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF5401 PF17380.2 CDS33355.2 - 0.15 10.1 0.3 0.2 9.7 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PPR_2 PF13041.6 CDS33356.2 - 0.004 17.3 0.3 0.39 11.0 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family PPR_1 PF12854.7 CDS33356.2 - 0.016 14.9 0.2 2.3 8.0 0.0 3.8 4 0 0 4 4 4 0 PPR repeat PPR_3 PF13812.6 CDS33356.2 - 0.17 12.0 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR PF01535.20 CDS33356.2 - 0.23 11.8 0.3 40 4.8 0.0 4.0 3 0 0 3 3 3 0 PPR repeat Rcd1 PF04078.13 CDS33357.1 - 0.00043 19.7 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF1730 PF08331.10 CDS33357.1 - 0.14 12.1 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Rcd1 PF04078.13 CDS33358.2 - 4.3e-116 386.7 0.6 4.9e-116 386.5 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PI31_Prot_C PF08577.11 CDS33359.1 - 5e-07 30.8 6.6 5e-07 30.8 6.6 2.3 3 0 0 3 3 3 1 PI31 proteasome regulator tRNA_int_end_N2 PF12928.7 CDS33360.2 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 CDS33360.2 - 0.0037 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1 PF01466.19 CDS33361.2 - 1e-25 89.6 0.9 1.8e-25 88.8 0.9 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDS33361.2 - 4.4e-18 65.2 0.1 9.9e-18 64.1 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Cadherin PF00028.17 CDS33362.1 - 1.7e-55 185.5 4.7 6.1e-19 68.3 0.1 8.7 7 3 0 7 7 7 7 Cadherin domain Cadherin_2 PF08266.12 CDS33362.1 - 1e-08 34.8 0.0 0.0036 17.1 0.0 3.6 3 1 0 3 3 3 2 Cadherin-like Tetraspanin PF00335.20 CDS33364.1 - 1.2e-40 139.7 19.9 1.3e-40 139.5 19.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2975 PF11188.8 CDS33364.1 - 6.6 6.6 12.0 1 9.2 1.6 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2975) Fungal_trans PF04082.18 CDS33365.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain TraB PF01963.17 CDS33368.1 - 3.3e-21 76.4 0.1 1.3e-18 67.9 0.0 2.2 2 0 0 2 2 2 2 TraB family BRF1 PF07741.13 CDS33368.1 - 0.005 17.2 1.1 0.0098 16.2 1.1 1.5 1 0 0 1 1 1 1 Brf1-like TBP-binding domain DXP_reductoisom PF02670.16 CDS33368.1 - 0.064 14.0 0.1 0.15 12.8 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LRR_6 PF13516.6 CDS33369.1 - 3.1e-09 36.1 4.4 0.34 11.1 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 CDS33369.1 - 0.06 13.1 0.6 23 4.8 0.2 4.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 CDS33369.1 - 0.11 12.9 2.3 27 5.3 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Inhibitor_I10 PF12559.8 CDS33369.1 - 0.16 12.3 0.3 0.4 11.0 0.2 1.7 1 1 0 1 1 1 0 Serine endopeptidase inhibitors Prominin PF05478.11 CDS33370.1 - 2.7e-17 62.0 7.5 3.3e-16 58.4 7.5 2.6 1 1 0 1 1 1 1 Prominin DUF1385 PF07136.11 CDS33370.1 - 0.004 16.5 1.3 0.011 15.1 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) Ribosomal_L18 PF17135.4 CDS33370.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e DUF443 PF04276.12 CDS33370.1 - 5.5 6.8 11.5 2.5 7.9 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DHHC PF01529.20 CDS33370.1 - 9.8 6.3 20.0 1.1 9.3 1.2 2.9 3 0 0 3 3 3 0 DHHC palmitoyltransferase MORN PF02493.20 CDS33371.1 - 9.6e-08 31.5 13.6 4.4e-06 26.3 1.3 4.8 5 1 0 5 5 5 3 MORN repeat SH3_2 PF07653.17 CDS33372.1 - 1.1e-12 47.5 0.0 9.1e-05 22.1 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 CDS33372.1 - 2e-09 36.9 0.0 3.6e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CDS33372.1 - 4.4e-06 26.5 1.0 0.034 14.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SAWADEE PF16719.5 CDS33373.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 SAWADEE domain EF-hand_6 PF13405.6 CDS33374.1 - 1.9e-08 33.5 1.6 0.00014 21.5 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDS33374.1 - 4.7e-08 33.4 2.9 9.4e-07 29.2 0.3 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS33374.1 - 9.5e-06 24.8 5.4 0.001 18.4 0.0 4.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CDS33374.1 - 0.0043 16.9 0.4 0.056 13.3 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 CDS33374.1 - 0.014 15.4 0.2 0.14 12.1 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand FancD2 PF14631.6 CDS33374.1 - 0.12 9.7 0.0 0.15 9.5 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease EF-hand_5 PF13202.6 CDS33374.1 - 0.66 9.6 3.9 1.8 8.2 0.0 3.4 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 CDS33375.1 - 1.4e-10 41.5 0.9 1.4e-10 41.5 0.9 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS33375.1 - 1.6e-10 40.0 2.3 1.3e-06 27.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDS33375.1 - 7.9e-07 28.2 6.7 3.7e-05 23.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS33375.1 - 4.7e-06 26.4 5.8 0.00012 21.9 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 CDS33375.1 - 0.0078 16.2 0.1 0.052 13.5 0.0 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CDS33375.1 - 0.036 14.9 0.1 0.058 14.3 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain EFhand_Ca_insen PF08726.10 CDS33375.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 CDS33375.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.5 4 0 0 4 4 4 0 EF hand KLRAQ PF10205.9 CDS33377.1 - 4.3e-10 39.7 6.6 4.3e-10 39.7 6.6 3.6 3 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 CDS33377.1 - 1.2e-08 34.4 8.1 1.2e-08 34.4 8.1 3.0 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 CDS33377.1 - 0.0056 16.7 12.1 0.026 14.6 0.2 4.2 3 1 2 5 5 5 1 Protein of unknown function (DUF1664) Leu_zip PF15294.6 CDS33377.1 - 0.011 15.3 3.6 0.011 15.3 3.6 3.3 2 2 0 2 2 2 0 Leucine zipper DUF1087 PF06465.13 CDS33377.1 - 0.066 13.3 0.8 4.6 7.3 0.2 2.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF2229 PF09989.9 CDS33377.1 - 0.15 11.7 5.2 0.57 9.8 0.9 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Filament PF00038.21 CDS33377.1 - 0.17 11.4 31.5 0.55 9.8 12.7 2.3 2 0 0 2 2 2 0 Intermediate filament protein ptaRNA1_toxin PF12703.7 CDS33377.1 - 0.36 10.9 2.4 0.38 10.8 0.4 2.0 2 1 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system CENP-F_leu_zip PF10473.9 CDS33377.1 - 0.92 9.5 38.1 0.17 11.9 8.4 4.6 3 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 CDS33377.1 - 7.6 4.3 19.3 2.5 5.9 8.4 2.4 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 CDS33377.1 - 9 5.4 15.9 0.037 13.2 0.8 2.8 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 PID PF00640.23 CDS33378.1 - 3.8e-25 88.5 0.9 8e-25 87.5 0.9 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) NumbF PF06311.12 CDS33378.1 - 6.5e-11 42.6 1.2 1.5e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 NUMB domain PID_2 PF14719.6 CDS33378.1 - 6.4e-05 22.9 0.2 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.13 CDS33378.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Transglut_core PF01841.19 CDS33379.1 - 0.0023 18.4 0.0 0.007 16.8 0.0 1.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Kelch_5 PF13854.6 CDS33380.1 - 4e-37 125.6 0.1 2.2e-05 24.3 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 CDS33380.1 - 4e-34 116.3 1.5 1.1e-07 32.0 0.0 7.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS33380.1 - 1.4e-32 111.5 1.0 6e-06 26.2 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CDS33380.1 - 7.7e-26 89.5 1.4 0.00092 19.4 0.0 7.1 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 CDS33380.1 - 1.9e-22 78.6 0.1 4.1e-05 23.1 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CDS33380.1 - 2.2e-19 68.6 0.5 0.0085 16.0 0.0 7.2 6 0 0 6 6 6 6 Kelch motif fn3 PF00041.21 CDS33380.1 - 7e-11 42.3 0.5 0.0059 16.9 0.1 4.5 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDS33380.1 - 0.039 14.5 0.0 1.2 9.8 0.0 3.3 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain TFIIA PF03153.13 CDS33380.1 - 4.5 7.2 10.4 0.55 10.2 5.4 2.0 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit I-set PF07679.16 CDS33381.2 - 0.00017 21.6 0.0 0.0046 17.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 CDS33381.2 - 0.037 14.2 1.0 0.086 13.0 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Pkinase PF00069.25 CDS33382.2 - 2e-45 155.2 0.0 3.2e-44 151.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33382.2 - 1.8e-15 57.0 0.0 1e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Baculo_gp64 PF03273.13 CDS33383.1 - 0.15 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family 7tm_1 PF00001.21 CDS33384.1 - 1.7e-08 34.1 2.1 2e-08 33.9 2.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS33384.1 - 0.31 10.3 11.4 1.5 8.1 11.4 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Col_cuticle_N PF01484.17 CDS33384.1 - 1.5 9.0 4.8 4.7 7.4 0.7 2.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain HTH_48 PF17906.1 CDS33385.1 - 0.0062 16.6 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 HTH domain in Mos1 transposase CLPTM1 PF05602.12 CDS33386.1 - 3.4e-79 266.9 0.5 4.4e-79 266.5 0.5 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) LIDHydrolase PF10230.9 CDS33387.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2766 PF10964.8 CDS33388.1 - 0.14 12.1 0.1 24 5.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2766) La PF05383.17 CDS33389.1 - 7.6e-22 77.1 0.1 1.3e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 La domain Laminin_II PF06009.12 CDS33390.1 - 0.21 11.6 16.3 0.53 10.3 1.0 3.8 1 1 2 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.12 CDS33390.1 - 0.32 11.0 10.6 0.86 9.6 3.5 3.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Haem_bd PF14376.6 CDS33390.1 - 0.56 10.2 6.1 5.7 6.9 0.1 3.0 3 0 0 3 3 3 0 Haem-binding domain DUF4407 PF14362.6 CDS33390.1 - 0.57 9.5 20.9 0.029 13.7 3.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CDS33390.1 - 1.4 8.9 15.8 12 5.9 3.5 4.0 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 CDS33390.1 - 2.1 8.3 15.4 12 5.8 2.0 4.1 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 CDS33390.1 - 4.8 7.0 19.1 0.6 9.9 0.6 4.2 3 1 1 4 4 4 0 Septum formation initiator Rpr2 PF04032.16 CDS33390.1 - 9.5 6.6 8.6 19 5.6 4.3 2.9 2 2 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vinculin PF01044.19 CDS33391.1 - 1.8e-64 218.5 9.0 4.1e-36 124.7 5.5 2.2 2 0 0 2 2 2 2 Vinculin family VBS PF08913.10 CDS33391.1 - 0.11 13.0 4.0 5.8 7.4 0.1 4.3 4 0 0 4 4 4 0 Vinculin Binding Site CAP_N PF01213.19 CDS33391.1 - 1.4 8.3 4.6 4.5 6.7 4.6 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal I_LWEQ PF01608.17 CDS33391.1 - 1.5 9.0 14.1 0.45 10.8 0.4 4.6 5 1 0 5 5 5 0 I/LWEQ domain PRIMA1 PF16101.5 CDS33391.1 - 2.3 8.3 13.5 11 6.1 6.0 3.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Ion_trans PF00520.31 CDS33392.2 - 7.9e-08 31.8 18.9 2.2e-07 30.4 18.9 1.7 1 1 0 1 1 1 1 Ion transport protein LSDAT_euk PF18139.1 CDS33392.2 - 0.0037 16.7 0.0 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 SLOG in TRPM Doppel PF11466.8 CDS33392.2 - 0.046 13.4 1.7 9.1 6.0 0.1 2.5 2 0 0 2 2 2 0 Prion-like protein Doppel DUF4795 PF16043.5 CDS33392.2 - 0.17 11.4 5.8 6.5 6.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) HTH_24 PF13412.6 CDS33394.2 - 0.0063 16.0 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CDS33394.2 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain RB_A PF01858.17 CDS33396.2 - 0.033 14.0 1.0 0.045 13.6 0.8 1.5 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain Ribosomal_L28e PF01778.17 CDS33397.1 - 3.4e-24 85.8 0.1 3.4e-24 85.8 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CDS33397.1 - 5.8e-20 71.8 16.1 5.8e-20 71.8 16.1 1.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region PfkB PF00294.24 CDS33398.1 - 1.2e-42 146.3 0.0 1.6e-41 142.6 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RVT_1 PF00078.27 CDS33399.1 - 0.0016 18.0 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lact-deh-memb PF09330.11 CDS33401.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding LisH PF08513.11 CDS33401.1 - 0.2 11.7 0.7 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 LisH Cdc6_C PF09079.11 CDS33402.1 - 2.5e-16 59.4 0.2 5.8e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 CDS33402.1 - 1.7e-11 44.7 0.0 4.7e-11 43.2 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDS33402.1 - 3.4e-10 40.3 0.0 7.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDS33402.1 - 8.5e-10 39.3 0.8 1.6e-08 35.2 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 CDS33402.1 - 1.2e-06 28.6 1.4 9.8e-06 25.6 0.2 2.3 2 0 0 2 2 2 1 AAA lid domain NACHT PF05729.12 CDS33402.1 - 4.1e-05 23.6 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 CDS33402.1 - 0.0023 17.5 0.0 0.0078 15.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CDS33402.1 - 0.0041 17.1 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CDS33402.1 - 0.0064 16.5 0.1 0.059 13.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDS33402.1 - 0.0087 16.4 0.4 0.031 14.6 0.4 1.9 1 1 0 1 1 1 1 AAA domain Methyltransf_18 PF12847.7 CDS33402.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_11 PF13086.6 CDS33402.1 - 0.053 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDS33402.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ORC5_C PF14630.6 CDS33402.1 - 0.065 12.7 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus AAA_18 PF13238.6 CDS33402.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 CDS33402.1 - 0.098 12.2 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF815 PF05673.13 CDS33402.1 - 0.13 11.4 0.0 4.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 CDS33402.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CDS33402.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CDS33402.1 - 0.18 11.5 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 CDS33402.1 - 0.18 11.8 0.0 0.55 10.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA12 PF10443.9 CDS33402.1 - 0.2 10.3 0.0 0.9 8.2 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein Chromo_shadow PF01393.19 CDS33403.1 - 8.1e-31 105.9 0.1 4.9e-28 97.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CDS33403.1 - 1.6e-22 79.2 1.3 2.3e-18 65.8 1.5 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SBD_N PF07005.11 CDS33403.1 - 0.098 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Sugar-binding N-terminal domain DUF3510 PF12022.8 CDS33404.1 - 0.088 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) TTRAP PF14203.6 CDS33404.1 - 0.24 11.4 0.8 0.88 9.6 0.1 2.3 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DEAD PF00270.29 CDS33406.1 - 2.8e-40 138.0 0.7 4.4e-40 137.3 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS33406.1 - 5.1e-30 104.1 0.2 2.3e-28 98.7 0.0 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS33406.1 - 6.5e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDS33406.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS33406.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bromodomain PF00439.25 CDS33407.1 - 1.2e-97 320.1 8.5 4.3e-20 71.6 0.4 6.4 6 0 0 6 6 6 5 Bromodomain BAH PF01426.18 CDS33407.1 - 2.7e-27 95.0 0.2 2.8e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.19 CDS33407.1 - 1e-12 48.3 0.2 2.2e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS33407.1 - 3.4e-09 37.1 0.4 1.1e-08 35.5 0.4 1.9 1 0 0 1 1 1 1 HMG-box domain Asparaginase_2 PF01112.18 CDS33408.1 - 1.6e-50 171.9 0.0 2.2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Mito_carr PF00153.27 CDS33409.1 - 2e-58 194.3 2.1 2.1e-20 72.4 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein HMD PF03201.16 CDS33409.1 - 0.11 12.8 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase UBX PF00789.20 CDS33410.1 - 2e-07 31.1 0.0 7.2e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 UBX domain Pyr_redox_2 PF07992.14 CDS33411.1 - 6.8e-66 222.5 3.1 1e-65 221.9 3.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDS33411.1 - 8.9e-38 128.9 0.0 2.6e-37 127.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDS33411.1 - 4.1e-21 75.3 6.5 5.4e-19 68.5 1.9 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDS33411.1 - 8.2e-12 45.2 6.8 6.9e-09 35.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDS33411.1 - 2.5e-11 43.4 4.7 1.2e-08 34.6 0.4 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDS33411.1 - 5.7e-10 38.8 5.3 2.6e-07 30.1 0.1 3.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 CDS33411.1 - 4.5e-09 36.4 0.6 0.00032 20.9 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CDS33411.1 - 4.7e-07 29.4 3.4 0.025 13.8 0.1 3.2 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 CDS33411.1 - 5.2e-07 29.1 12.7 5e-06 25.8 0.1 3.2 3 1 1 4 4 4 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDS33411.1 - 2.3e-06 27.1 1.4 0.00059 19.2 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CDS33411.1 - 1.1e-05 24.8 0.6 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CDS33411.1 - 1.9e-05 24.0 0.8 0.054 12.6 0.1 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CDS33411.1 - 2.1e-05 23.4 11.6 0.0015 17.3 0.3 3.6 4 0 0 4 4 4 3 HI0933-like protein DAO PF01266.24 CDS33411.1 - 0.00059 19.5 9.7 2.9 7.4 0.0 4.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CDS33411.1 - 0.00069 19.0 1.2 0.26 10.6 0.4 2.5 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 CDS33411.1 - 0.02 15.4 0.1 1.3 9.5 0.1 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 CDS33411.1 - 0.022 13.8 1.6 1.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 CDS33411.1 - 0.031 14.2 0.7 0.031 14.2 0.7 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CDS33411.1 - 0.037 14.5 0.3 0.55 10.7 0.2 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CDS33411.1 - 0.11 13.1 0.3 20 5.8 0.0 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent LacI PF00356.21 CDS33411.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family WD40 PF00400.32 CDS33412.1 - 3.2e-18 65.7 21.6 0.032 15.1 0.1 10.4 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS33412.1 - 1.1e-09 38.4 0.0 0.0025 18.1 0.0 6.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HlyIII PF03006.20 CDS33413.1 - 4.6e-71 239.1 22.7 5.7e-71 238.8 22.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3165 PF11364.8 CDS33413.1 - 0.11 12.8 3.3 1 9.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) zf-RING_2 PF13639.6 CDS33414.2 - 1.7e-12 47.5 5.5 1.7e-12 47.5 5.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS33414.2 - 3.3e-10 39.6 4.0 8.7e-10 38.3 4.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS33414.2 - 5e-10 39.5 5.8 1.9e-09 37.6 5.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDS33414.2 - 5.7e-09 35.9 3.4 1.8e-08 34.2 3.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS33414.2 - 2.4e-07 30.5 4.6 6.6e-07 29.1 4.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDS33414.2 - 6e-07 29.1 1.3 1.9e-06 27.5 1.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger CENP-F_leu_zip PF10473.9 CDS33414.2 - 1.8e-05 24.8 0.8 1.8e-05 24.8 0.8 3.4 2 1 1 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.6 CDS33414.2 - 1.8e-05 24.5 7.8 5.4e-05 23.0 7.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS33414.2 - 0.00023 21.1 6.2 0.00023 21.1 6.2 2.2 2 1 1 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS33414.2 - 0.00033 20.4 13.0 0.052 13.4 5.8 2.7 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDS33414.2 - 0.0012 18.4 5.1 0.0026 17.3 5.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CDS33414.2 - 0.0013 18.8 4.9 0.0043 17.1 4.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ATG16 PF08614.11 CDS33414.2 - 0.019 15.2 10.9 1.1 9.5 5.0 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Rx_N PF18052.1 CDS33414.2 - 0.024 14.9 1.3 0.024 14.9 1.3 2.1 2 0 0 2 2 1 0 Rx N-terminal domain FliD_C PF07195.12 CDS33414.2 - 0.026 14.0 3.4 0.46 9.9 0.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMF_DNA_bd PF12329.8 CDS33414.2 - 0.079 13.0 0.3 0.079 13.0 0.3 2.9 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CDS33414.2 - 0.14 11.0 18.1 0.33 9.8 2.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 CDS33414.2 - 0.18 12.4 14.4 0.29 11.8 1.5 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Pox_A_type_inc PF04508.12 CDS33414.2 - 0.23 11.4 2.0 1.2 9.1 0.2 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.12 CDS33414.2 - 0.25 11.4 19.7 1.4 9.0 1.6 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein OrfB_IS605 PF01385.19 CDS33414.2 - 0.26 11.5 9.1 0.1 12.8 1.6 2.7 2 0 0 2 2 2 0 Probable transposase zf-RING-like PF08746.11 CDS33414.2 - 0.35 11.2 4.8 1.4 9.3 4.8 2.2 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 CDS33414.2 - 0.51 10.5 7.1 0.23 11.6 2.8 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF948 PF06103.11 CDS33414.2 - 0.51 10.6 1.3 44 4.4 0.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CDS33414.2 - 0.62 10.4 14.7 4.6 7.6 6.9 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NYD-SP28_assoc PF14775.6 CDS33414.2 - 0.78 9.9 6.7 0.46 10.6 2.1 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain GAS PF13851.6 CDS33414.2 - 0.93 8.8 22.3 1.9 7.8 11.4 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CDS33414.2 - 1.3 9.2 15.1 16 5.7 0.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Med4 PF10018.9 CDS33414.2 - 1.4 8.5 7.9 17 5.1 4.2 2.5 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PspA_IM30 PF04012.12 CDS33414.2 - 2.5 7.6 11.3 4.7 6.7 0.5 2.3 2 0 0 2 2 2 0 PspA/IM30 family Laminin_II PF06009.12 CDS33414.2 - 2.6 8.1 10.0 1.1 9.3 0.2 2.9 2 1 0 2 2 2 0 Laminin Domain II PRKG1_interact PF15898.5 CDS33414.2 - 3 8.8 16.4 6.4 7.7 0.6 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain FadA PF09403.10 CDS33414.2 - 3.1 8.3 12.0 0.46 11.0 3.9 2.9 2 1 0 2 2 2 0 Adhesion protein FadA YscO PF07321.12 CDS33414.2 - 5.9 6.8 15.9 7.2 6.6 7.0 3.0 2 1 0 2 2 2 0 Type III secretion protein YscO DUF724 PF05266.14 CDS33414.2 - 6.2 6.6 11.4 18 5.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 CDS33414.2 - 6.4 6.8 14.8 13 5.8 0.2 3.7 2 1 1 3 3 3 0 Prefoldin subunit FapA PF03961.13 CDS33414.2 - 9 4.8 14.0 6.5 5.2 7.9 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A EF-hand_13 PF17958.1 CDS33416.1 - 8.9e-32 108.8 0.0 3.7e-31 106.8 0.0 2.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CDS33416.1 - 3.2e-18 65.9 0.6 9e-18 64.5 0.4 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDS33416.1 - 2.9e-05 23.4 0.1 0.0019 17.6 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 CDS33416.1 - 0.0011 18.3 0.1 0.014 14.9 0.0 2.8 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 CDS33416.1 - 0.0033 17.2 0.1 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS33416.1 - 0.014 15.7 0.3 2.2 8.6 0.1 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDS33416.1 - 0.044 13.6 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair DUF4187 PF13821.6 CDS33416.1 - 0.056 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) MMS19_N PF14500.6 CDS33417.1 - 5.2e-49 167.2 0.1 5.2e-49 167.2 0.1 2.8 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 CDS33417.1 - 0.92 9.9 3.8 5.3 7.5 0.0 3.8 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 CDS33417.1 - 5.7 7.5 8.1 66 4.2 0.3 5.1 5 0 0 5 5 5 0 HEAT repeat Tfb2 PF03849.14 CDS33418.1 - 3.4e-122 407.8 0.0 4.6e-122 407.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CDS33418.1 - 3.3e-26 91.5 1.2 7.8e-26 90.3 1.2 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain HTH_Tnp_Tc3_1 PF11427.8 CDS33418.1 - 0.063 13.1 0.2 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Tc3 transposase Helicase_C_3 PF13625.6 CDS33418.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ubiquitin_4 PF18036.1 CDS33419.1 - 2e-11 43.7 0.0 4.8e-06 26.5 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin-like domain LIN52 PF10044.9 CDS33420.1 - 4.5e-32 110.6 0.1 4.9e-32 110.5 0.1 1.0 1 0 0 1 1 1 1 Retinal tissue protein Methyltransf_5 PF01795.19 CDS33421.2 - 1.3e-81 274.5 0.0 9.5e-80 268.4 0.0 2.6 1 1 0 1 1 1 1 MraW methylase family WD40 PF00400.32 CDS33421.2 - 5e-07 30.3 5.1 1.9 9.5 0.1 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Methyltransf_31 PF13847.6 CDS33421.2 - 0.0046 16.8 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CDS33421.2 - 0.037 14.7 0.0 0.28 11.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CDS33421.2 - 0.038 13.5 0.0 0.41 10.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain HHH_3 PF12836.7 CDS33421.2 - 0.063 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif ANAPC4_WD40 PF12894.7 CDS33421.2 - 0.14 12.5 0.0 5.4 7.4 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S6e PF01092.19 CDS33422.1 - 5.1e-58 194.5 0.0 5.1e-58 194.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 CDS33422.1 - 1.5 7.8 8.6 2.1 7.4 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_M PF01031.20 CDS33423.1 - 1.5e-99 332.9 0.2 1.5e-99 332.9 0.2 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CDS33423.1 - 1.7e-53 181.1 0.1 4.1e-53 179.9 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDS33423.1 - 4.4e-23 81.2 4.3 9.3e-23 80.2 4.3 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CDS33423.1 - 8.3e-08 32.7 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CDS33423.1 - 0.00013 22.1 0.2 0.0055 16.8 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase PUF PF00806.19 CDS33424.1 - 3.3e-65 212.2 10.3 4.3e-09 35.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF445 PF04286.12 CDS33424.1 - 0.00062 19.7 2.0 0.0016 18.3 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF445) Phage_clamp_A PF16790.5 CDS33424.1 - 0.075 13.5 0.5 0.18 12.2 0.5 1.6 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit PseudoU_synth_2 PF00849.22 CDS33425.1 - 4.1e-30 105.0 0.0 7e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase LRR_4 PF12799.7 CDS33426.1 - 2e-10 40.7 22.6 5.6e-07 29.8 3.8 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS33426.1 - 2e-09 37.1 13.5 5.9e-08 32.4 2.4 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CDS33426.1 - 7.5e-06 25.6 0.2 1.3e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat mRNA_cap_C PF03919.15 CDS33426.1 - 0.03 14.9 0.7 0.069 13.8 0.3 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain LRR_6 PF13516.6 CDS33426.1 - 0.18 12.0 9.8 1.9 8.7 0.4 4.0 5 0 0 5 5 5 0 Leucine Rich repeat SPATA24 PF15175.6 CDS33426.1 - 0.23 11.3 4.9 4.3 7.2 0.5 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 LRR_1 PF00560.33 CDS33426.1 - 0.73 10.6 11.9 17 6.4 0.8 4.4 5 1 0 5 5 5 0 Leucine Rich Repeat Cadherin PF00028.17 CDS33427.1 - 1.5e-72 240.1 3.2 2.5e-11 43.9 0.0 7.6 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CDS33427.1 - 8.9e-11 41.5 0.1 1.9e-06 27.6 0.0 4.5 4 0 0 4 4 4 2 Cadherin-like DUF975 PF06161.11 CDS33427.1 - 3.2 7.5 6.8 14 5.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Tmemb_9 PF05434.11 CDS33427.1 - 5.7 6.8 5.2 0.74 9.7 0.7 1.8 2 0 0 2 2 2 0 TMEM9 FANCI_S4 PF14678.6 CDS33428.2 - 2.6e-52 177.4 2.7 2.8e-49 167.5 0.9 3.5 2 1 0 2 2 2 1 FANCI solenoid 4 FANCI_S2 PF14676.6 CDS33428.2 - 1.9e-37 129.1 1.2 1.9e-37 129.1 1.2 3.0 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 CDS33428.2 - 4.5e-06 26.1 0.1 0.087 12.1 0.0 3.5 2 1 0 2 2 2 2 FANCI helical domain 2 Pkinase_Tyr PF07714.17 CDS33429.2 - 7.3e-46 156.5 0.0 1.1e-33 116.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CDS33429.2 - 9.8e-34 116.9 0.0 5e-31 108.0 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain SAM_KSR1 PF13543.6 CDS33429.2 - 1.9e-08 34.5 0.0 3.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kdo PF06293.14 CDS33429.2 - 0.023 14.1 0.6 0.04 13.3 0.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS33429.2 - 0.089 12.7 0.2 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family AlphaC_C PF17480.2 CDS33429.2 - 1.2 9.3 3.5 1.2 9.3 1.0 2.1 2 0 0 2 2 2 0 AlphaC C-terminal Vac17 PF17321.2 CDS33429.2 - 1.4 8.3 7.7 0.18 11.3 0.4 2.2 2 0 0 2 2 2 0 Vacuole-related protein 17 C1_1 PF00130.22 CDS33429.2 - 2.1 8.3 10.7 0.1 12.5 3.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eRF1_1 PF03463.15 CDS33430.1 - 2.8e-40 137.3 0.2 4.4e-40 136.7 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CDS33430.1 - 2.1e-24 86.4 0.0 4.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDS33430.1 - 1.9e-23 83.1 0.0 3.9e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Sas10 PF09368.10 CDS33431.1 - 1.1e-23 83.4 6.0 2.1e-23 82.6 6.0 1.5 1 0 0 1 1 1 1 Sas10 C-terminal domain 7TM_GPCR_Sri PF10327.9 CDS33431.1 - 0.25 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Abhydrolase_6 PF12697.7 CDS33432.1 - 9.8e-20 72.1 0.0 1.1e-11 45.7 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDS33432.1 - 1.5e-12 47.7 0.0 4.4e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDS33432.1 - 4.2e-10 39.3 0.1 9.2e-10 38.2 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDS33432.1 - 6.4e-05 22.8 0.1 0.00012 21.9 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CDS33432.1 - 7.2e-05 23.0 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 CDS33432.1 - 0.0006 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 CDS33432.1 - 0.0025 16.7 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CDS33432.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 CDS33432.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) CIA30 PF08547.12 CDS33433.1 - 2.8e-28 99.0 0.0 1.3e-26 93.6 0.0 2.4 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.22 CDS33434.1 - 2.1e-60 200.4 0.0 1.3e-18 66.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS33434.1 - 5.1e-12 45.5 0.0 0.00021 20.9 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS33434.1 - 0.00014 21.7 0.0 0.0027 17.5 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDS33434.1 - 0.045 13.8 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif zf-RING_2 PF13639.6 CDS33435.1 - 2.3e-11 43.9 7.8 8.2e-11 42.1 7.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDS33435.1 - 1.7e-08 34.1 3.0 4.1e-08 32.8 3.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDS33435.1 - 2.8e-08 33.5 7.9 8.9e-08 31.8 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS33435.1 - 8.4e-07 28.8 6.2 8.4e-07 28.8 6.2 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS33435.1 - 8.4e-05 22.8 9.1 8.4e-05 22.8 9.1 2.8 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS33435.1 - 0.0003 20.7 4.7 0.00098 19.0 4.7 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDS33435.1 - 0.00043 20.2 8.4 0.0013 18.7 8.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDS33435.1 - 0.00065 19.5 5.2 0.0021 17.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDS33435.1 - 0.0065 16.3 8.9 0.02 14.8 8.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDS33435.1 - 0.022 14.8 2.0 0.069 13.2 2.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CDS33435.1 - 0.043 13.9 2.2 0.12 12.4 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CDS33435.1 - 0.06 13.0 2.8 0.16 11.6 2.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 CDS33435.1 - 1.1 9.3 5.8 0.5 10.3 0.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prefoldin PF02996.17 CDS33436.1 - 1e-25 90.0 2.8 1e-25 90.0 2.8 1.5 1 1 0 1 1 1 1 Prefoldin subunit CHDCT2 PF08074.11 CDS33436.1 - 0.0054 16.9 3.5 0.015 15.5 3.4 1.7 1 1 0 1 1 1 1 CHDCT2 (NUC038) domain Osmo_CC PF08946.10 CDS33436.1 - 0.0063 16.7 0.1 0.0063 16.7 0.1 2.9 3 1 0 3 3 3 1 Osmosensory transporter coiled coil Lebercilin PF15619.6 CDS33436.1 - 0.17 11.5 6.1 0.59 9.8 0.4 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HJURP_C PF12347.8 CDS33436.1 - 1.2 9.2 3.6 1.3 9.1 0.7 2.4 2 1 1 3 3 3 0 Holliday junction regulator protein family C-terminal repeat Glyco_hydro_3 PF00933.21 CDS33437.1 - 8.4e-36 123.9 0.0 2.5e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CDS33437.1 - 9.7e-30 104.1 0.0 1.6e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CDS33437.1 - 3.1e-08 33.6 0.0 6.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain RNA_pol_Rpb2_3 PF04565.16 CDS33437.1 - 0.047 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Laminin_EGF PF00053.24 CDS33438.1 - 1.9e-112 367.3 264.6 1.1e-10 41.5 16.0 14.5 14 0 0 14 14 14 13 Laminin EGF domain Laminin_N PF00055.17 CDS33438.1 - 1.1e-62 211.7 0.2 1.1e-62 211.7 0.2 3.4 4 1 1 5 5 5 1 Laminin N-terminal (Domain VI) DUF848 PF05852.11 CDS33438.1 - 0.005 17.0 1.7 0.005 17.0 1.7 4.2 2 1 3 5 5 5 1 Gammaherpesvirus protein of unknown function (DUF848) Synaptonemal_3 PF15191.6 CDS33438.1 - 0.0059 16.4 0.9 0.0059 16.4 0.9 4.4 4 1 0 5 5 5 1 Synaptonemal complex central element protein 3 YolD PF08863.10 CDS33438.1 - 0.3 11.2 7.0 0.28 11.3 3.8 2.5 2 0 0 2 2 2 0 YolD-like protein DUF1664 PF07889.12 CDS33438.1 - 7.9 6.5 33.0 0.07 13.2 1.6 5.8 4 2 3 7 7 7 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 CDS33438.1 - 9.2 6.1 30.9 1.1 9.1 1.1 6.2 4 2 1 6 6 6 0 Sec34-like family zf-C2H2 PF00096.26 CDS33439.1 - 4.3e-14 52.1 11.0 2.5e-06 27.6 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33439.1 - 1.9e-10 40.7 10.2 0.00025 21.6 0.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS33439.1 - 9.2e-08 31.9 8.0 0.011 15.7 0.1 3.5 2 1 1 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CDS33439.1 - 1.2e-07 31.9 4.6 0.016 15.6 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CDS33439.1 - 4.2e-07 30.1 15.1 0.00024 21.4 0.5 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS33439.1 - 2.7e-06 27.5 3.0 0.2 12.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS33439.1 - 0.0023 18.2 7.9 0.027 14.8 2.6 2.6 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDS33439.1 - 0.0073 16.0 1.3 0.24 11.2 0.1 2.5 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-BED PF02892.15 CDS33439.1 - 0.0088 16.0 5.1 0.66 10.0 0.6 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 CDS33439.1 - 0.0099 16.2 7.0 0.05 14.0 6.7 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CDS33439.1 - 0.016 15.9 4.5 0.75 10.5 0.2 3.3 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 CDS33439.1 - 0.024 15.1 0.9 0.078 13.5 0.1 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Ribosomal_L44 PF00935.19 CDS33439.1 - 0.025 15.0 2.5 0.13 12.8 1.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L44 zf-C2HC_2 PF13913.6 CDS33439.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type BolA PF01722.18 CDS33439.1 - 0.073 13.4 1.2 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_9 PF16293.5 CDS33439.1 - 0.26 11.2 1.9 29 4.6 0.1 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) TF_Zn_Ribbon PF08271.12 CDS33439.1 - 0.27 10.8 3.2 12 5.5 0.1 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding C1_2 PF03107.16 CDS33439.1 - 0.69 10.3 9.1 87 3.6 7.1 3.5 2 1 0 2 2 2 0 C1 domain zinc-ribbons_6 PF07191.12 CDS33439.1 - 1.2 9.2 5.9 15 5.7 1.2 2.6 1 1 1 2 2 2 0 zinc-ribbons Elf1 PF05129.13 CDS33439.1 - 1.3 9.1 7.0 16 5.6 7.0 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf_C2H2_ZHX PF18387.1 CDS33439.1 - 2.5 7.8 5.6 10 5.8 0.1 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Ribosomal_L37ae PF01780.19 CDS33439.1 - 5 7.3 9.8 8 6.6 0.3 3.8 2 1 0 3 3 3 0 Ribosomal L37ae protein family GAGA PF09237.11 CDS33439.1 - 5.2 7.0 9.1 0.95 9.3 2.6 2.8 1 1 2 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.10 CDS33439.1 - 7.8 6.7 6.8 9.6 6.4 1.9 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 CDS33440.1 - 0.0042 17.5 1.4 0.0042 17.5 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33440.1 - 0.1 13.5 1.2 0.1 13.5 1.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS33441.1 - 3.5e-13 49.2 15.2 2.6e-06 27.6 2.0 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33441.1 - 1.4e-11 44.2 12.0 0.00026 21.6 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS33441.1 - 1.7e-07 31.3 16.5 9.7e-06 25.8 0.8 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDS33441.1 - 1.9e-07 30.9 8.4 0.012 15.6 0.1 3.6 2 1 1 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CDS33441.1 - 8.3e-07 29.2 6.6 0.017 15.5 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS33441.1 - 5.9e-06 26.4 3.5 0.21 11.9 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS33441.1 - 0.0021 18.3 9.0 0.015 15.6 3.3 2.6 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDS33441.1 - 0.0034 17.1 2.4 0.25 11.1 0.1 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CDS33441.1 - 0.0082 16.5 7.4 0.031 14.6 7.1 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 CDS33441.1 - 0.023 15.2 0.9 0.083 13.4 0.1 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 CDS33441.1 - 0.074 13.0 0.1 0.074 13.0 0.1 2.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type BolA PF01722.18 CDS33441.1 - 0.088 13.1 1.2 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_3rep PF18868.1 CDS33441.1 - 0.15 12.8 5.6 1.4 9.6 2.2 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 CDS33441.1 - 0.17 12.0 9.6 0.87 9.7 0.9 2.8 2 1 0 3 3 2 0 BED zinc finger zf-C2H2_9 PF16293.5 CDS33441.1 - 0.23 11.3 2.1 29 4.6 0.1 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 CDS33441.1 - 0.25 11.5 3.2 1 9.5 0.5 2.5 2 1 0 2 2 2 0 Zinc ribbon domain Ribosomal_L44 PF00935.19 CDS33441.1 - 0.28 11.7 4.1 0.89 10.1 2.5 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 Vps36-NZF-N PF16988.5 CDS33441.1 - 0.39 10.1 2.2 1.8 8.0 0.1 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain C1_2 PF03107.16 CDS33441.1 - 0.39 11.1 7.9 3.8 7.9 2.2 3.1 1 1 1 2 2 2 0 C1 domain TF_Zn_Ribbon PF08271.12 CDS33441.1 - 0.56 9.8 5.0 12 5.5 0.1 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding Elf1 PF05129.13 CDS33441.1 - 0.86 9.7 8.2 0.71 10.0 3.3 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 CDS33441.1 - 1.2 9.2 6.1 14 5.8 1.4 2.6 1 1 1 2 2 2 0 zinc-ribbons zf_C2H2_ZHX PF18387.1 CDS33441.1 - 3.2 7.4 6.2 11 5.7 0.1 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DZR PF12773.7 CDS33441.1 - 7.3 6.7 6.6 49 4.1 6.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 CDS33441.1 - 7.9 6.4 8.5 7.7 6.5 0.1 3.1 3 0 0 3 3 3 0 HIT zinc finger Spidroin_MaSp PF11260.8 CDS33442.1 - 0.17 12.2 2.7 0.55 10.6 0.7 2.2 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 ABC_tran PF00005.27 CDS33443.1 - 4.2e-34 118.0 0.0 7.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDS33443.1 - 2.6e-29 102.8 4.0 2.6e-29 102.8 4.0 2.7 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 CDS33443.1 - 4e-07 29.7 0.0 7.7e-05 22.2 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDS33443.1 - 3.2e-05 24.4 0.0 8.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDS33443.1 - 0.0019 17.9 0.1 0.008 15.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CDS33443.1 - 0.0028 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 CDS33443.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDS33443.1 - 0.018 15.3 0.0 0.084 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDS33443.1 - 0.034 14.2 0.1 0.088 12.9 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDS33443.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS33443.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CDS33443.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ThiF PF00899.21 CDS33444.1 - 8.3e-23 81.0 0.0 1.3e-22 80.3 0.0 1.3 1 1 0 1 1 1 1 ThiF family Tropomyosin_1 PF12718.7 CDS33444.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Mis12 PF05859.12 CDS33445.1 - 0.011 15.8 1.1 0.16 12.0 1.1 2.4 1 1 0 1 1 1 0 Mis12 protein NPH-II PF12011.8 CDS33445.1 - 0.039 13.8 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 RNA helicase NPH-II UQ_con PF00179.26 CDS33446.1 - 2.2e-44 150.5 0.0 3e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDS33446.1 - 0.0016 18.3 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CDS33446.1 - 0.0028 17.9 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CDS33446.1 - 0.0069 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B ANTH PF07651.16 CDS33447.1 - 9.9e-57 192.0 2.3 1.4e-56 191.5 2.3 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CDS33447.1 - 1.9e-10 40.8 0.5 3.8e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 ENTH domain Chal_sti_synt_C PF02797.15 CDS33447.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain CDC45 PF02724.14 CDS33447.1 - 3.1 6.0 6.7 6.6 4.9 6.7 1.5 1 0 0 1 1 1 0 CDC45-like protein Dus PF01207.17 CDS33448.1 - 1.2e-53 182.2 1.8 3.6e-53 180.7 1.8 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) dsrm PF00035.26 CDS33448.1 - 1.7e-07 31.8 0.1 3.2e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsRBD2 PF17842.1 CDS33448.1 - 0.00012 22.3 3.8 0.0019 18.4 0.5 3.2 2 1 2 4 4 4 1 Double-stranded RNA binding domain 2 His_biosynth PF00977.21 CDS33448.1 - 0.0032 17.0 0.0 0.0083 15.6 0.0 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 CDS33448.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Myosin_head PF00063.21 CDS33449.2 - 3e-228 759.4 3.1 3e-228 759.4 3.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CDS33449.2 - 0.00033 20.2 3.1 0.0016 18.1 3.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_N PF02736.19 CDS33449.2 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CDS33449.2 - 0.0023 18.4 0.0 0.0071 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Coleoptericin PF06286.11 CDS33449.2 - 0.0096 16.0 0.2 6.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Coleoptericin AAA_22 PF13401.6 CDS33449.2 - 0.012 15.8 0.0 0.059 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain HMGL-like PF00682.19 CDS33449.2 - 0.014 15.0 0.0 0.76 9.3 0.0 2.4 2 0 0 2 2 2 0 HMGL-like Zeta_toxin PF06414.12 CDS33449.2 - 0.037 13.3 1.4 0.11 11.8 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Spectrin PF00435.21 CDS33449.2 - 0.086 13.3 7.4 4.3 7.9 0.8 2.9 2 0 0 2 2 2 0 Spectrin repeat AAA_19 PF13245.6 CDS33449.2 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4795 PF16043.5 CDS33449.2 - 3.6 7.1 17.9 15 5.1 3.9 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Polyketide_cyc2 PF10604.9 CDS33450.1 - 4.7e-06 26.9 0.0 5.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CDS33450.1 - 0.0074 16.5 0.0 0.0099 16.1 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LSM PF01423.22 CDS33453.1 - 3.3e-08 33.1 0.0 5.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain IPI_T4 PF11634.8 CDS33453.1 - 0.052 13.5 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 PQ-loop PF04193.14 CDS33454.1 - 3.2e-28 97.3 10.3 2.6e-16 59.1 2.1 3.0 2 0 0 2 2 2 2 PQ loop repeat Thymidylat_synt PF00303.19 CDS33455.1 - 7.9e-110 366.2 0.0 9.1e-110 366.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase UQ_con PF00179.26 CDS33456.1 - 1.7e-28 99.0 0.0 2.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDS33456.1 - 0.0034 17.2 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 CDS33456.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Gpi16 PF04113.14 CDS33457.1 - 1.9e-77 261.0 0.1 4.6e-76 256.5 0.1 2.2 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component APG12 PF04110.13 CDS33458.2 - 9.8e-25 86.8 0.0 3.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CDS33458.2 - 1.5e-06 28.4 0.0 2.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Rad60-SLD PF11976.8 CDS33458.2 - 0.2 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Arnt_C PF18583.1 CDS33459.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Pkinase PF00069.25 CDS33464.1 - 6e-49 166.8 0.1 6e-49 166.8 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33464.1 - 6.2e-32 110.9 0.1 1.1e-31 110.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.28 CDS33465.1 - 5.3e-77 259.3 0.0 7e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CDS33465.1 - 7.4e-63 212.4 14.9 1.4e-62 211.5 14.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.14 CDS33465.1 - 4.6e-11 42.5 18.4 1.4e-10 41.0 18.4 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.25 CDS33466.1 - 1.4e-72 244.2 0.0 1.6e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33466.1 - 9.1e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDS33466.1 - 4.4e-05 22.6 0.0 0.0016 17.4 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDS33466.1 - 0.0015 17.9 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CDS33466.1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDS33466.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1899 PF08953.11 CDS33468.1 - 4.5e-31 106.5 0.0 8.7e-31 105.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CDS33468.1 - 6.8e-21 73.9 0.0 1.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDS33468.1 - 4.2e-08 33.7 2.6 0.016 16.0 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS33468.1 - 0.00025 21.3 0.1 1.4 9.2 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 CDS33469.1 - 4.6e-32 109.7 0.1 1.2e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDS33469.1 - 2.2e-09 37.3 0.0 0.00097 19.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS33469.1 - 0.0024 17.9 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS33469.1 - 0.03 14.3 0.1 0.086 12.9 0.1 1.7 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 CDS33469.1 - 0.21 11.3 0.4 25 4.7 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain SPX PF03105.19 CDS33469.1 - 2 8.2 5.8 2.8 7.8 5.8 1.1 1 0 0 1 1 1 0 SPX domain F_actin_cap_B PF01115.17 CDS33470.1 - 1.5e-29 103.3 0.2 2.7e-29 102.5 0.2 1.4 1 1 0 1 1 1 1 F-actin capping protein, beta subunit Med27 PF11571.8 CDS33471.1 - 4.6e-20 71.8 0.1 1.7e-19 69.9 0.1 2.1 1 0 0 1 1 1 1 Mediator complex subunit 27 SH3_1 PF00018.28 CDS33471.1 - 2.3e-14 52.7 0.0 3.4e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CDS33471.1 - 2.3e-12 46.6 0.2 3.8e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CDS33471.1 - 1.5e-08 34.2 0.0 0.00019 21.0 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain DNA_ligase_A_N PF04675.14 CDS33472.2 - 3.7e-33 115.3 0.1 1.5e-32 113.3 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 CDS33472.2 - 2.8e-28 99.0 0.0 4.6e-21 75.4 0.0 3.4 2 1 1 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 CDS33472.2 - 2e-13 50.8 0.1 4.3e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 CDS33472.2 - 6.8e-05 23.2 0.0 0.19 12.1 0.0 2.9 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDS33472.2 - 8.3e-05 22.9 0.0 0.001 19.4 0.1 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 CDS33472.2 - 0.12 12.5 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ssDNA-exonuc_C PF10141.9 CDS33472.2 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain zf-RING_2 PF13639.6 CDS33474.1 - 7.7e-08 32.5 16.0 1.6e-07 31.5 16.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS33474.1 - 1.6e-06 27.9 13.5 3e-06 26.9 13.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS33474.1 - 3.8e-06 26.8 12.6 6.9e-06 26.0 12.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDS33474.1 - 1.4e-05 24.9 12.7 1.4e-05 24.9 12.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS33474.1 - 2.3e-05 24.2 13.6 3.9e-05 23.4 13.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS33474.1 - 0.00028 21.1 11.0 0.0011 19.2 11.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDS33474.1 - 0.077 12.9 14.1 0.15 11.9 14.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDS33474.1 - 0.085 12.5 10.1 0.13 11.9 10.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CDS33474.1 - 0.14 12.2 11.8 0.35 10.9 11.8 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 CDS33474.1 - 2.1 8.2 8.5 4.4 7.2 8.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.32 CDS33475.1 - 2.2e-07 31.5 3.3 0.00024 21.8 0.1 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3959 PF13105.6 CDS33475.1 - 0.33 10.4 0.6 0.51 9.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) P53 PF00870.18 CDS33476.1 - 4.4e-21 75.5 0.0 1.5e-19 70.6 0.0 2.3 1 1 0 1 1 1 1 P53 DNA-binding domain B-block_TFIIIC PF04182.12 CDS33477.2 - 1.9e-07 31.1 0.4 5.7e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC DUF4005 PF13178.6 CDS33477.2 - 9.9 6.9 13.9 41 4.9 0.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4005) CBFD_NFYB_HMF PF00808.23 CDS33478.1 - 5.1e-29 100.3 0.3 7.7e-29 99.8 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS33478.1 - 0.00039 20.8 0.0 0.00062 20.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDS33478.1 - 0.0046 17.1 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 CDS33478.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit T2SS-T3SS_pil_N PF13629.6 CDS33478.1 - 0.019 14.7 0.3 0.036 13.8 0.3 1.4 1 0 0 1 1 1 0 Pilus formation protein N terminal region BetaGal_dom3 PF13363.6 CDS33478.1 - 0.055 13.0 0.4 0.13 11.9 0.1 1.7 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 Sigma70_ner PF04546.13 CDS33478.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region EGF PF00008.27 CDS33479.1 - 3.6e-08 33.6 32.0 0.0017 18.6 1.3 5.0 4 1 0 4 4 4 4 EGF-like domain Laminin_G_2 PF02210.24 CDS33479.1 - 8.3e-08 32.9 0.0 0.00011 22.8 0.0 2.4 2 0 0 2 2 2 2 Laminin G domain Plasmod_Pvs28 PF06247.11 CDS33479.1 - 0.00067 19.9 10.1 0.2 12.0 4.9 2.8 2 0 0 2 2 2 2 Pvs28 EGF domain cEGF PF12662.7 CDS33479.1 - 0.00091 19.1 11.9 0.074 13.0 0.3 3.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.7 CDS33479.1 - 0.026 15.1 2.7 0.026 15.1 2.7 5.6 5 0 0 5 5 5 0 Human growth factor-like EGF TAFA PF12020.8 CDS33479.1 - 0.11 12.9 2.8 0.52 10.8 2.8 2.2 1 0 0 1 1 1 0 TAFA family EGF_CA PF07645.15 CDS33479.1 - 5.6 7.3 25.8 0.054 13.7 4.1 4.0 3 1 1 4 4 4 0 Calcium-binding EGF domain RGS PF00615.19 CDS33481.1 - 1.8e-33 115.3 2.2 2.7e-33 114.7 2.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain adh_short PF00106.25 CDS33482.1 - 1.3e-13 50.9 0.0 2.2e-09 37.1 0.0 2.5 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33482.1 - 2.2e-08 34.0 0.0 6e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CDS33482.1 - 0.0063 15.9 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Glyco_trans_4_2 PF13477.6 CDS33482.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Peptidase_M14 PF00246.24 CDS33483.1 - 6.6e-62 209.9 0.0 9.6e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Yippee-Mis18 PF03226.14 CDS33483.1 - 4.8e-10 39.6 0.1 2.8e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AstE_AspA PF04952.14 CDS33483.1 - 0.00036 19.7 0.1 0.001 18.2 0.1 1.8 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 CDS33483.1 - 0.0094 15.4 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) dCache_1 PF02743.18 CDS33483.1 - 0.026 14.3 0.1 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Cache domain RPN5_C PF18098.1 CDS33486.1 - 5.8e-17 61.5 4.3 1e-16 60.7 4.3 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 CDS33486.1 - 0.0051 17.3 0.1 0.0085 16.6 0.1 1.4 1 0 0 1 1 1 1 PCI domain Fzo_mitofusin PF04799.13 CDS33486.1 - 0.02 14.4 0.8 0.025 14.1 0.8 1.1 1 0 0 1 1 1 0 fzo-like conserved region UEV PF05743.13 CDS33486.1 - 0.038 13.9 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 UEV domain Yippee-Mis18 PF03226.14 CDS33487.1 - 5.1e-11 42.7 0.1 6.1e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 CDS33487.1 - 0.052 13.5 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII RIG-I_C-RD PF11648.8 CDS33487.1 - 0.08 13.2 0.1 0.099 12.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I ADK PF00406.22 CDS33488.1 - 8.6e-60 201.2 0.0 1.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDS33488.1 - 2.6e-25 89.4 0.0 4.5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CDS33488.1 - 7.7e-16 57.8 0.0 6.5e-15 54.8 0.0 2.5 1 1 1 2 2 2 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 CDS33488.1 - 1.8e-09 38.2 0.8 0.00034 21.0 0.0 2.3 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CDS33488.1 - 3.3e-05 24.4 0.0 7.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDS33488.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDS33488.1 - 0.0033 17.7 0.1 0.0085 16.4 0.1 1.8 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 CDS33488.1 - 0.0077 16.2 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CDS33488.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CDS33488.1 - 0.045 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase NTPase_1 PF03266.15 CDS33488.1 - 0.085 12.8 0.4 0.23 11.3 0.0 1.9 3 0 0 3 3 3 0 NTPase Mg_chelatase PF01078.21 CDS33488.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UCR_TM PF02921.14 CDS33489.1 - 2.6e-19 69.5 1.5 5e-19 68.5 1.5 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region zf-CCCH PF00642.24 CDS33489.1 - 5e-14 51.8 35.2 3.4e-05 23.6 0.1 5.6 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rieske PF00355.26 CDS33489.1 - 1e-10 41.4 0.1 2.9e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain zf-CCCH_4 PF18044.1 CDS33489.1 - 2.2e-10 40.0 30.9 0.00011 21.9 0.4 5.2 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDS33489.1 - 9.6e-10 38.2 46.6 4.3e-06 26.6 2.3 6.7 6 1 0 6 6 6 4 Zinc finger domain zf-CCCH_3 PF15663.5 CDS33489.1 - 3.3e-08 33.7 8.5 3.3e-08 33.7 8.5 2.8 1 1 1 2 2 2 1 Zinc-finger containing family Torus PF16131.5 CDS33489.1 - 1.1e-06 29.3 35.9 0.00086 20.0 0.3 6.1 1 1 5 6 6 6 5 Torus domain zf-CCHC PF00098.23 CDS33489.1 - 4.3e-06 26.5 15.9 5.6e-06 26.2 3.7 3.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDS33489.1 - 1.7 8.4 8.2 11 5.8 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 CDS33489.1 - 6.2 6.7 10.9 10 5.9 0.2 3.6 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CDS33489.1 - 10 6.8 41.1 3 8.5 1.5 6.0 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger PrmA PF06325.13 CDS33492.2 - 4.2e-08 32.9 0.1 7.1e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CDS33492.2 - 1e-07 32.5 0.0 5.1e-07 30.3 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS33492.2 - 2.6e-05 24.8 0.0 0.00013 22.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDS33492.2 - 3.2e-05 23.5 0.1 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PRMT5 PF05185.16 CDS33492.2 - 5.9e-05 23.0 0.2 0.00019 21.3 0.1 1.9 1 1 1 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 CDS33492.2 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 CDS33492.2 - 0.00072 19.5 0.8 0.0013 18.6 0.1 1.8 2 0 0 2 2 2 1 PRMT5 oligomerisation domain Methyltransf_9 PF08003.11 CDS33492.2 - 0.0033 16.4 0.1 0.011 14.7 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 CDS33492.2 - 0.0067 16.1 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 CDS33492.2 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS33492.2 - 0.0088 15.8 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF2039 PF10217.9 CDS33493.1 - 2.1e-30 104.9 14.3 4e-30 104.0 14.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 CDS33493.1 - 0.032 14.2 8.1 0.074 13.0 8.1 1.7 1 0 0 1 1 1 0 zinc-ribbons UPF0697 PF15117.6 CDS33493.1 - 0.12 12.5 0.1 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 MFS_1 PF07690.16 CDS33494.1 - 3.3e-20 72.3 39.4 5.1e-15 55.3 21.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 CDS33495.1 - 2.5e-21 76.0 0.3 6e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain F5_F8_type_C PF00754.25 CDS33495.1 - 6.1e-11 42.5 0.2 0.00031 20.9 0.1 2.6 2 0 0 2 2 2 2 F5/8 type C domain BACK PF07707.15 CDS33495.1 - 1.2e-08 35.0 0.1 3.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch G-patch PF01585.23 CDS33497.1 - 5.2e-09 35.9 1.8 1.2e-08 34.7 1.8 1.6 1 0 0 1 1 1 1 G-patch domain zf-CCCH PF00642.24 CDS33497.1 - 2.7e-06 27.1 2.7 7.1e-06 25.8 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FapA PF03961.13 CDS33497.1 - 0.15 10.7 3.3 0.29 9.7 3.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-CCCH_4 PF18044.1 CDS33497.1 - 0.58 10.0 2.3 1.1 9.2 2.3 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDS33497.1 - 1.5 9.0 3.5 3.4 7.8 3.5 1.7 1 0 0 1 1 1 0 Zinc finger domain RRM_1 PF00076.22 CDS33498.1 - 5.9e-17 61.2 0.0 8.5e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 CDS33499.1 - 2.9e-96 322.6 0.0 3.6e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDS33499.1 - 0.00036 21.5 0.1 0.0011 19.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CDS33500.1 - 2.2e-92 309.9 0.0 3e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDS33500.1 - 0.0086 17.0 0.0 0.025 15.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CDS33501.1 - 4.7e-77 258.9 0.0 6.3e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33501.1 - 1.8e-44 152.0 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CDS33501.1 - 2.2e-13 50.7 0.1 1.6e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 CDS33501.1 - 6.5e-09 35.5 0.0 9.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDS33501.1 - 0.0021 17.7 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CDS33501.1 - 0.0078 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 CDS33501.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF4994 PF16385.5 CDS33501.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Kdo PF06293.14 CDS33501.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS33501.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 CDS33502.1 - 4.5e-19 69.1 0.2 3.9e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDS33502.1 - 1.6e-15 58.4 0.0 2.6e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDS33502.1 - 2.3e-12 46.7 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDS33502.1 - 1.9e-08 34.3 0.2 6.2e-06 26.1 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 CDS33502.1 - 7.4e-05 22.5 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 CDS33502.1 - 0.00027 20.5 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 CDS33502.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Lipase_2 PF01674.18 CDS33502.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Palm_thioest PF02089.15 CDS33502.1 - 0.013 15.4 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydro_lipase PF04083.16 CDS33502.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF915 PF06028.11 CDS33502.1 - 0.13 11.6 0.0 4.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Vps52 PF04129.12 CDS33503.1 - 2.5e-112 376.2 0.4 8.6e-112 374.5 0.4 1.9 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CDS33503.1 - 2.4e-08 32.9 13.9 1.2e-07 30.6 10.0 3.0 2 1 0 2 2 2 1 Exocyst complex component Sec3 DUF1664 PF07889.12 CDS33503.1 - 0.0044 17.0 1.0 0.029 14.4 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDS33503.1 - 0.045 12.6 0.7 0.078 11.8 0.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CDS33503.1 - 0.048 13.7 1.8 0.25 11.4 0.8 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2316 PF10078.9 CDS33503.1 - 0.12 12.6 0.1 0.44 10.8 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) HAP1_N PF04849.13 CDS33503.1 - 0.12 11.5 2.2 5.2 6.2 0.0 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region GramPos_pilinD1 PF16555.5 CDS33503.1 - 0.18 12.0 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain SCO1-SenC PF02630.14 CDS33506.2 - 0.037 13.9 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC HLH PF00010.26 CDS33506.2 - 0.042 13.8 0.9 0.042 13.8 0.9 2.2 2 1 1 3 3 3 0 Helix-loop-helix DNA-binding domain HLH PF00010.26 CDS33507.1 - 0.019 14.9 0.8 0.019 14.9 0.8 2.0 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain HLH PF00010.26 CDS33509.1 - 0.00012 22.0 1.7 0.00015 21.6 0.9 1.7 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Plasmid_parti PF01672.16 CDS33509.1 - 0.0097 16.5 0.2 0.019 15.6 0.2 1.6 1 1 0 1 1 1 1 Putative plasmid partition protein RED_C PF07807.11 CDS33511.1 - 0.0052 17.3 1.0 0.0052 17.3 1.0 1.7 2 0 0 2 2 2 1 RED-like protein C-terminal region DUF5343 PF17278.2 CDS33511.1 - 0.038 14.1 0.3 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5343) HLH PF00010.26 CDS33511.1 - 1.3 9.1 7.6 0.37 10.8 1.3 2.9 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain Beach PF02138.18 CDS33512.1 - 2e-98 329.2 0.0 3.9e-98 328.2 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CDS33512.1 - 3.4e-07 30.3 0.0 8.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CDS33512.1 - 0.018 15.9 0.4 0.09 13.7 0.4 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat Sec7 PF01369.20 CDS33513.1 - 5e-63 212.1 0.2 1.2e-62 210.8 0.2 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDS33513.1 - 5.1e-43 146.7 7.2 5.1e-43 146.7 7.2 4.0 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CDS33513.1 - 4.2e-37 127.5 1.5 1.8e-36 125.4 1.5 2.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CDS33513.1 - 2.4e-24 85.0 5.9 1.2e-22 79.5 0.1 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DUF1539 PF07560.11 CDS33513.1 - 0.2 11.7 1.0 10 6.2 0.0 3.8 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) Ribosomal_S6 PF01250.17 CDS33514.1 - 2.6e-08 34.0 0.0 3.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RRM_1 PF00076.22 CDS33515.1 - 1.2e-16 60.3 0.1 7.5e-08 32.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1636 PF07845.11 CDS33515.1 - 0.014 15.9 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) ApoO PF09769.9 CDS33516.2 - 0.0026 17.7 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O GBP PF02263.19 CDS33517.2 - 2.9e-73 246.3 0.0 4.4e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 CDS33517.2 - 0.057 12.8 1.4 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Med10 PF09748.9 CDS33518.1 - 3.2e-27 94.9 0.0 4.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Mt_ATP-synt_D PF05873.12 CDS33519.1 - 2.7e-41 141.0 0.7 3.5e-41 140.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4795 PF16043.5 CDS33519.1 - 0.21 11.1 3.2 0.32 10.6 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Dpy-30 PF05186.13 CDS33520.2 - 2.1e-12 46.5 0.1 3.3e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 CDS33520.2 - 6.6e-07 29.5 0.0 9.7e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Adenylate kinase Hydin_ADK PF17213.3 CDS33520.2 - 0.0059 16.9 0.0 0.0059 16.9 0.0 3.0 4 0 0 4 4 4 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 CDS33520.2 - 0.021 15.3 6.4 0.28 11.6 0.1 3.9 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 CDS33520.2 - 0.049 14.2 0.1 0.29 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF1635 PF07795.11 CDS33520.2 - 4.2 7.2 13.2 0.27 11.1 7.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4220 PF13968.6 CDS33522.1 - 0.082 12.3 0.7 0.11 11.8 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) Dynein_light PF01221.18 CDS33523.1 - 2e-10 40.9 0.0 2.2e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SpoVIF PF14069.6 CDS33523.1 - 0.0012 18.6 0.3 0.0014 18.4 0.3 1.1 1 0 0 1 1 1 1 Stage VI sporulation protein F HWE_HK PF07536.14 CDS33523.1 - 0.024 15.3 0.4 0.04 14.6 0.4 1.4 1 1 0 1 1 1 0 HWE histidine kinase FERM_C PF09380.10 CDS33524.1 - 3.4e-20 72.2 0.7 7.1e-20 71.2 0.7 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.18 CDS33524.1 - 1.6e-13 51.1 0.0 1.6e-13 51.1 0.0 2.4 2 1 0 2 2 2 1 FERM central domain FA PF08736.11 CDS33524.1 - 1.4e-09 37.8 2.3 1.4e-09 37.8 2.3 2.8 2 0 0 2 2 2 1 FERM adjacent (FA) FERM_N PF09379.10 CDS33524.1 - 1.7e-08 34.2 0.0 4.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain Carn_acyltransf PF00755.20 CDS33525.1 - 5.4e-187 623.0 0.0 6.2e-187 622.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 CDS33526.1 - 1.4e-38 132.7 16.4 8e-37 127.0 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDS33526.1 - 1 8.1 17.6 0.21 10.4 3.8 2.3 1 1 1 2 2 2 0 MFS_1 like family Lipase_GDSL_2 PF13472.6 CDS33527.1 - 7.8e-21 75.3 0.0 1.2e-20 74.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDS33527.1 - 4.1e-14 53.0 0.0 1.8e-13 51.0 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PDZ PF00595.24 CDS33529.1 - 4.7e-20 71.7 0.7 9.7e-20 70.7 0.4 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CDS33529.1 - 9e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 CDS33529.1 - 9.5e-07 29.3 0.0 0.0012 19.3 0.0 2.6 2 1 0 2 2 2 2 PH domain PH_17 PF18012.1 CDS33529.1 - 6.9e-06 25.7 0.9 9.2e-05 22.1 0.6 2.4 2 0 0 2 2 2 1 PH domain PDZ_2 PF13180.6 CDS33529.1 - 1.1e-05 25.6 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CDS33529.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain CUE PF02845.16 CDS33531.1 - 3.1e-11 42.7 0.0 8.5e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain HSF_DNA-bind PF00447.17 CDS33532.1 - 5.5e-27 94.2 0.3 5.5e-27 94.2 0.3 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding DUF2203 PF09969.9 CDS33532.1 - 0.0043 17.8 0.1 0.0087 16.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) Cluap1 PF10234.9 CDS33532.1 - 0.07 12.5 0.3 0.13 11.6 0.3 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Zwint PF15556.6 CDS33532.1 - 0.18 11.3 2.7 0.31 10.5 2.7 1.3 1 0 0 1 1 1 0 ZW10 interactor HALZ PF02183.18 CDS33532.1 - 0.22 11.8 1.1 0.59 10.4 1.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Voltage_CLC PF00654.20 CDS33533.1 - 3e-81 273.4 27.0 3e-81 273.4 27.0 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CDS33533.1 - 1.8e-17 63.5 0.4 2.7e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain INSIG PF07281.12 CDS33533.1 - 6.4 6.4 7.9 19 4.8 0.6 3.2 2 1 1 3 3 3 0 Insulin-induced protein (INSIG) DUF3887 PF13026.6 CDS33534.1 - 0.19 12.5 0.8 0.29 12.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Arm-DNA-bind_4 PF14657.6 CDS33534.1 - 0.46 10.3 1.3 0.49 10.2 0.2 1.6 2 0 0 2 2 2 0 Arm DNA-binding domain zf-C2H2_11 PF16622.5 CDS33534.1 - 1.7 8.4 4.2 4.7 7.1 0.3 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2206 PF09971.9 CDS33535.1 - 0.26 10.0 4.1 0.3 9.8 4.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Transgly_assoc PF04226.13 CDS33536.1 - 0.092 13.0 6.4 0.092 13.0 3.1 2.1 1 1 1 2 2 2 0 Transglycosylase associated protein Ank_5 PF13857.6 CDS33537.1 - 2.7e-07 30.8 0.1 0.0015 18.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33537.1 - 0.00022 21.8 0.0 0.00038 21.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS33537.1 - 0.01 16.4 0.1 0.31 11.7 0.1 2.8 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33537.1 - 0.039 14.5 0.1 1.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 CDS33537.1 - 0.11 13.0 0.2 19 5.9 0.2 2.4 2 0 0 2 2 2 0 Ankyrin repeat SUI1 PF01253.22 CDS33538.1 - 2e-14 53.9 0.1 1.8e-13 50.8 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CDS33538.1 - 1.4e-08 35.3 0.2 3.6e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 Pre-PUA-like domain DUF1947 PF09183.10 CDS33538.1 - 0.0016 18.7 0.1 0.0058 16.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) DUF2183 PF09949.9 CDS33538.1 - 0.17 12.3 0.4 0.53 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) OSTMP1 PF09777.9 CDS33539.1 - 1.1e-16 60.9 3.5 1.7e-16 60.4 3.5 1.3 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor DUF4428 PF14471.6 CDS33539.1 - 0.016 15.1 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF4658 PF15555.6 CDS33539.1 - 0.26 11.4 1.0 0.79 9.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) zf-CHCC PF10276.9 CDS33540.1 - 4e-19 68.4 3.6 5.4e-19 68.0 3.6 1.2 1 0 0 1 1 1 1 Zinc-finger domain Thiolase_C PF02803.18 CDS33540.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Thiolase, C-terminal domain DUF572 PF04502.13 CDS33541.1 - 6.6e-87 292.2 5.3 7.4e-87 292.1 5.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Beta_protein PF14350.6 CDS33541.1 - 0.052 13.0 0.4 4.8 6.5 0.2 2.1 2 0 0 2 2 2 0 Beta protein HMG_box PF00505.19 CDS33542.1 - 5.1e-25 87.7 4.0 1.2e-24 86.5 4.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDS33542.1 - 5.5e-10 39.7 1.5 1.4e-09 38.4 1.5 1.6 1 0 0 1 1 1 1 HMG-box domain Tex_N PF09371.10 CDS33546.1 - 8.4e-41 139.6 0.0 1.7e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CDS33546.1 - 1e-39 135.8 0.0 2.9e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 Tex protein YqgF-like domain HHH_3 PF12836.7 CDS33546.1 - 1.6e-21 76.3 0.1 3.5e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 CDS33546.1 - 1.2e-10 42.2 0.0 3.9e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 CDS33546.1 - 8.3e-09 35.7 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 CDS33546.1 - 2.9e-07 30.8 0.0 1e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDS33546.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 T2SSK PF03934.13 CDS33546.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K SNF2_N PF00176.23 CDS33547.2 - 3.2e-50 170.8 0.1 6.1e-50 169.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS33547.2 - 2.9e-16 59.8 0.4 1.5e-14 54.3 0.0 3.6 4 0 0 4 4 3 1 Helicase conserved C-terminal domain TPR_2 PF07719.17 CDS33547.2 - 2.2e-06 27.3 10.7 0.037 14.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ResIII PF04851.15 CDS33547.2 - 5.6e-06 26.5 0.0 3.5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_16 PF13432.6 CDS33547.2 - 0.00016 22.2 2.2 0.86 10.3 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS33547.2 - 0.00065 19.3 0.5 1.1 9.0 0.0 2.8 2 0 0 2 2 2 2 TPR repeat P16-Arc PF04699.14 CDS33547.2 - 0.017 15.6 10.7 0.025 15.1 0.2 4.4 2 2 2 4 4 4 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TPR_1 PF00515.28 CDS33547.2 - 0.021 14.6 0.3 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDS33547.2 - 0.047 14.0 12.0 0.19 12.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS33547.2 - 0.091 13.0 0.3 0.75 10.1 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDS33547.2 - 0.59 10.3 3.0 1.9 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PaaB PF06243.11 CDS33547.2 - 2 8.7 3.7 23 5.3 0.0 3.1 4 0 0 4 4 2 0 Phenylacetic acid degradation B HSNSD PF12062.8 CDS33548.1 - 4.9e-98 329.0 0.0 2.4e-90 303.6 0.1 2.1 2 0 0 2 2 2 2 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 CDS33548.1 - 2.6e-25 89.4 0.1 5.1e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CDS33548.1 - 9.4e-10 39.2 4.0 0.0015 19.0 1.0 3.5 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 CDS33548.1 - 0.035 14.0 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase family F_actin_bind PF08919.10 CDS33548.1 - 0.16 12.1 0.0 0.53 10.4 0.0 1.9 1 0 0 1 1 1 0 F-actin binding DUF667 PF05018.13 CDS33549.1 - 1.2e-76 256.5 0.1 1.4e-76 256.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Noggin PF05806.12 CDS33550.1 - 1.4e-26 93.7 14.1 1.6e-25 90.3 14.1 2.3 1 1 0 1 1 1 1 Noggin Cul7 PF11515.8 CDS33550.1 - 0.09 13.1 0.7 0.25 11.6 0.7 1.7 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 OrfB_IS605 PF01385.19 CDS33550.1 - 5.2 7.3 8.1 5.5 7.2 7.0 1.6 1 1 0 1 1 1 0 Probable transposase RNase_T PF00929.24 CDS33551.1 - 4.6e-29 102.1 0.0 5.5e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease LRR_4 PF12799.7 CDS33552.1 - 0.82 10.2 21.7 0.23 12.0 4.8 4.9 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) IBR PF01485.21 CDS33553.1 - 1.9e-21 76.0 42.8 3.6e-14 52.7 5.3 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CDS33553.1 - 0.00049 20.1 7.1 0.00049 20.1 7.1 4.7 5 1 0 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDS33553.1 - 0.0032 17.8 8.5 0.0032 17.8 8.5 5.2 3 3 3 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS33553.1 - 0.008 16.0 5.0 0.008 16.0 5.0 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS33553.1 - 0.015 15.2 10.1 0.015 15.2 10.1 4.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS33553.1 - 0.019 14.9 11.9 0.019 14.9 11.9 4.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-FPG_IleRS PF06827.14 CDS33553.1 - 0.26 11.2 11.6 2.2 8.2 0.4 4.6 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Clat_adaptor_s PF01217.20 CDS33554.1 - 1.9e-58 196.4 7.0 2.1e-58 196.3 7.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SHR3_chaperone PF08229.11 CDS33554.1 - 0.047 12.7 0.1 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Alba PF01918.21 CDS33555.1 - 2.5e-05 24.0 0.0 0.00054 19.7 0.0 2.2 2 0 0 2 2 2 2 Alba Usp PF00582.26 CDS33556.1 - 7e-25 88.2 0.1 1.6e-24 87.0 0.1 1.6 1 1 0 1 1 1 1 Universal stress protein family PA26 PF04636.13 CDS33557.1 - 1.5e-80 271.3 0.0 2e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Acetyltransf_1 PF00583.25 CDS33558.1 - 1e-16 61.2 0.1 1.3e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS33558.1 - 1.1e-10 41.7 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS33558.1 - 3.5e-10 39.9 0.0 5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 CDS33558.1 - 0.0013 17.4 0.0 0.023 13.2 0.0 2.0 1 1 1 2 2 2 1 Arginine N-succinyltransferase beta subunit Acetyltransf_CG PF14542.6 CDS33558.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase His_Phos_2 PF00328.22 CDS33559.1 - 2.3e-106 356.4 0.3 3.3e-106 355.9 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDS33559.1 - 5.4e-41 138.7 0.2 1.1e-40 137.7 0.2 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CDS33559.1 - 0.00017 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain SnAC PF14619.6 CDS33559.1 - 0.0058 17.2 0.0 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Arm PF00514.23 CDS33560.1 - 5.1e-63 207.3 11.4 2.2e-11 43.4 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CDS33560.1 - 1e-15 57.9 3.2 1.9e-15 57.1 3.2 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CDS33560.1 - 9.5e-14 50.7 6.0 6.2e-13 48.1 3.5 2.6 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CDS33560.1 - 1.2e-12 48.1 0.1 0.0049 17.2 0.0 5.5 1 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 CDS33560.1 - 1.9e-10 41.0 5.8 0.00039 20.9 0.0 5.7 4 3 3 7 7 7 3 HEAT-like repeat HEAT PF02985.22 CDS33560.1 - 5.8e-06 26.1 5.0 0.83 10.1 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat V-ATPase_H_C PF11698.8 CDS33560.1 - 0.0041 17.2 2.9 2.1 8.5 0.1 3.1 3 1 0 3 3 3 2 V-ATPase subunit H RICTOR_V PF14668.6 CDS33560.1 - 0.0058 16.8 6.2 7.7 6.8 0.0 4.7 2 2 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 CDS33560.1 - 0.024 13.9 0.1 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 V-ATPase subunit H DUF3361 PF11841.8 CDS33560.1 - 0.057 13.4 0.7 36 4.3 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) CTNNBL PF08216.11 CDS33560.1 - 0.069 13.3 3.2 6.4 7.0 0.0 3.7 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear PIN_9 PF18477.1 CDS33560.1 - 0.15 12.3 1.4 0.54 10.6 0.2 2.3 2 0 0 2 2 2 0 PIN like domain Sec34 PF04136.15 CDS33562.1 - 1.3e-37 128.9 11.7 1.3e-37 128.9 11.7 3.0 4 0 0 4 4 4 1 Sec34-like family Phage_int_SAM_1 PF02899.17 CDS33562.1 - 0.037 14.3 0.1 0.59 10.5 0.0 2.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Fmp27_WPPW PF10359.9 CDS33562.1 - 0.11 11.3 9.2 0.082 11.8 5.0 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ING PF12998.7 CDS33562.1 - 0.35 11.5 10.0 3.9 8.1 0.7 3.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ABC2_membrane_3 PF12698.7 CDS33562.1 - 0.71 8.9 2.3 1.3 8.0 2.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein BLOC1_2 PF10046.9 CDS33562.1 - 2.7 8.4 12.6 0.49 10.7 6.4 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RIH_assoc PF08454.11 CDS33562.1 - 5.1 7.0 20.5 0.32 10.9 0.9 4.7 4 1 0 4 4 4 0 RyR and IP3R Homology associated NPV_P10 PF05531.12 CDS33562.1 - 5.5 7.5 7.1 4.9 7.7 1.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cyclin_N PF00134.23 CDS33563.1 - 3.2e-12 46.3 0.5 6.6e-12 45.3 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CDS33563.1 - 7.9e-08 32.6 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 CDS33563.1 - 0.0027 17.8 1.0 0.38 10.8 0.1 3.0 2 1 0 2 2 2 2 Cyclin, C-terminal domain Importin_rep_4 PF18808.1 CDS33564.1 - 3.4e-24 84.9 0.8 3.4e-24 84.9 0.8 4.9 5 0 0 5 5 4 1 Importin repeat HEAT PF02985.22 CDS33564.1 - 1.3e-23 81.0 2.1 0.00026 21.0 0.0 10.5 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.6 CDS33564.1 - 6.2e-18 65.0 3.4 2e-06 28.1 0.1 9.1 6 4 2 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.7 CDS33564.1 - 1.6e-15 57.5 0.5 1.4e-05 25.6 0.0 6.9 5 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CDS33564.1 - 3e-15 56.3 6.0 1.2e-06 28.9 0.0 8.7 10 1 1 11 11 10 2 HEAT-like repeat Cnd1 PF12717.7 CDS33564.1 - 1.6e-09 38.0 0.1 6.5e-05 23.0 0.0 5.3 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 CDS33564.1 - 4.6e-08 33.1 0.8 0.95 9.4 0.0 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 CDS33564.1 - 3.5e-06 25.9 0.9 0.0022 16.6 0.0 4.3 2 2 2 4 4 4 2 Adaptin N terminal region IBN_N PF03810.19 CDS33564.1 - 5.4e-05 23.0 0.4 0.00055 19.8 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Importin_rep_6 PF18829.1 CDS33564.1 - 0.00011 22.3 2.8 0.00024 21.2 0.5 2.9 3 1 0 3 3 2 1 Importin repeat 6 MMS19_C PF12460.8 CDS33564.1 - 0.00032 19.9 0.5 0.017 14.3 0.0 3.7 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CDS33564.1 - 0.00037 20.1 0.1 5.9 6.4 0.0 4.8 4 0 0 4 4 4 1 CLASP N terminal Arm PF00514.23 CDS33564.1 - 0.0015 18.5 3.0 0.4 10.8 0.1 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 CDS33564.1 - 0.0027 17.3 3.0 2.1 7.8 0.0 3.9 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 CDS33564.1 - 0.0039 16.9 1.3 6 6.6 0.0 5.0 4 1 1 6 6 6 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.6 CDS33564.1 - 0.0068 16.1 0.1 29 4.3 0.1 5.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) Gcn1_N PF12074.8 CDS33564.1 - 0.064 12.5 0.1 0.87 8.8 0.0 2.9 3 1 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Cohesin_HEAT PF12765.7 CDS33564.1 - 0.088 13.1 0.0 0.85 10.0 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Importin_rep_5 PF18816.1 CDS33564.1 - 0.094 13.0 0.0 0.41 11.0 0.0 2.2 1 0 0 1 1 1 0 Importin repeat RINT1_TIP1 PF04437.13 CDS33565.1 - 1.3e-62 212.3 0.0 2e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Planc_extracel PF07595.12 CDS33565.1 - 7.7 6.5 5.7 1.6 8.7 0.5 2.5 2 0 0 2 2 2 0 Planctomycete extracellular TruB_N PF01509.18 CDS33566.1 - 2.7e-24 86.2 0.1 2e-20 73.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.12 CDS33566.1 - 1.3e-23 82.8 0.0 4.2e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CDS33566.1 - 6.9e-22 77.4 2.2 2e-21 75.9 0.2 2.6 3 0 0 3 3 3 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CDS33566.1 - 1.7e-13 50.3 0.4 3.5e-13 49.3 0.4 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CDS33566.1 - 0.0089 16.3 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 UPF0113 PUA domain TMEM223 PF14640.6 CDS33566.1 - 0.16 12.2 0.1 1.5 9.0 0.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 223 RRM_1 PF00076.22 CDS33567.1 - 1.4e-19 69.6 0.1 7.9e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tmemb_cc2 PF10267.9 CDS33567.1 - 5.7 6.0 10.7 0.39 9.8 1.7 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein APG5 PF04106.12 CDS33569.1 - 4.5e-46 157.3 0.0 5.7e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Pkinase PF00069.25 CDS33570.2 - 2.6e-54 184.4 0.0 2.6e-38 131.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33570.2 - 2.3e-23 82.8 0.0 5.5e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CDS33570.2 - 9.7e-05 22.4 0.6 0.04 13.8 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS33570.2 - 0.00038 19.5 1.1 0.00073 18.6 0.5 1.8 1 1 1 2 2 2 1 Haspin like kinase domain WD40 PF00400.32 CDS33570.2 - 0.0077 17.1 10.4 5.8 8.0 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Kinase-like PF14531.6 CDS33570.2 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CdvA PF18822.1 CDS33570.2 - 0.021 14.7 0.3 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain RteC PF09357.10 CDS33570.2 - 0.068 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 RteC protein Pkinase_C PF00433.24 CDS33570.2 - 5.1 7.9 6.6 1 10.1 1.0 3.0 2 0 0 2 2 2 0 Protein kinase C terminal domain HTH_48 PF17906.1 CDS33572.1 - 7.2e-07 29.2 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase MFS_1 PF07690.16 CDS33573.1 - 1e-22 80.6 34.8 2.7e-17 62.7 18.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDS33573.1 - 1.6e-17 63.5 6.5 1.6e-17 63.5 6.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CDS33573.1 - 0.0024 17.2 5.4 0.0024 17.2 5.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ERCC4 PF02732.15 CDS33574.1 - 2.2e-17 63.7 0.0 9e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain LapA_dom PF06305.11 CDS33575.1 - 0.0011 18.8 1.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF1218 PF06749.12 CDS33575.1 - 0.0036 17.8 0.0 0.0043 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1218) Peptidase_U4 PF03419.13 CDS33575.1 - 0.0059 15.9 0.1 0.0065 15.8 0.1 1.0 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Vpu PF00558.19 CDS33575.1 - 0.006 16.3 0.1 0.02 14.6 0.0 1.7 1 1 1 2 2 2 1 Vpu protein TMEMspv1-c74-12 PF11044.8 CDS33575.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.6 2 0 0 2 2 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SLAC1 PF03595.17 CDS33575.1 - 0.018 14.3 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3429 PF11911.8 CDS33575.1 - 0.021 15.1 0.2 0.026 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) DUF2232 PF09991.9 CDS33575.1 - 0.027 13.7 0.0 0.028 13.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) LPG_synthase_TM PF03706.13 CDS33575.1 - 0.034 13.7 0.0 0.037 13.6 0.0 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TssO PF17561.2 CDS33575.1 - 0.036 14.2 0.3 0.036 14.2 0.3 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF4131 PF13567.6 CDS33575.1 - 0.036 13.7 0.1 0.2 11.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 CDS33575.1 - 0.14 10.9 0.2 0.16 10.7 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BT1 PF03092.16 CDS33575.1 - 0.14 10.3 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 BT1 family ABC2_membrane_3 PF12698.7 CDS33575.1 - 0.17 11.0 4.2 0.2 10.7 4.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3341 PF11821.8 CDS33575.1 - 0.17 11.5 0.9 0.26 10.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Lig_chan PF00060.26 CDS33575.1 - 0.24 11.2 0.7 0.32 10.8 0.0 1.5 2 0 0 2 2 2 0 Ligand-gated ion channel DUF5305 PF17231.2 CDS33575.1 - 0.26 10.7 0.5 0.38 10.1 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) YtpI PF14007.6 CDS33575.1 - 0.95 9.6 6.2 1.3 9.2 0.4 2.3 1 1 1 2 2 2 0 YtpI-like protein SieB PF14163.6 CDS33575.1 - 1.8 8.1 3.3 7.5 6.0 2.4 1.9 1 1 1 2 2 2 0 Super-infection exclusion protein B Ribosomal_L18A PF01775.17 CDS33576.1 - 8.3e-55 184.1 0.3 1e-54 183.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A HEAT PF02985.22 CDS33577.1 - 0.0032 17.6 0.5 25 5.5 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat Brix PF04427.18 CDS33578.2 - 6.1e-33 114.6 0.6 6.3e-27 94.9 0.2 2.2 2 0 0 2 2 2 2 Brix domain ALC PF17527.2 CDS33578.2 - 8e-05 22.3 1.1 0.11 12.2 0.0 2.9 3 0 0 3 3 3 2 Phage ALC protein PGM_PMM_I PF02878.16 CDS33578.2 - 0.078 12.7 0.0 10 5.8 0.0 2.6 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I CaM-KIIN PF15170.6 CDS33578.2 - 0.09 12.9 0.0 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor Pkinase PF00069.25 CDS33579.1 - 7.5e-36 123.9 0.0 1.1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33579.1 - 2.7e-20 72.7 0.0 4.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase COBRA1 PF06209.13 CDS33580.1 - 6.8e-36 124.1 3.0 3.3e-18 65.8 0.4 3.9 4 0 0 4 4 4 3 Cofactor of BRCA1 (COBRA1) V-SNARE_C PF12352.8 CDS33581.1 - 4.2e-05 23.8 4.1 0.00016 21.9 0.2 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Filament PF00038.21 CDS33581.1 - 0.0051 16.4 2.1 0.0051 16.4 2.1 1.5 2 0 0 2 2 2 1 Intermediate filament protein DUF1664 PF07889.12 CDS33581.1 - 0.0052 16.8 2.5 0.15 12.1 0.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) SlyX PF04102.12 CDS33581.1 - 0.038 14.6 6.1 0.26 11.9 0.3 3.2 3 0 0 3 3 3 0 SlyX DUF5089 PF17002.5 CDS33581.1 - 0.044 13.6 6.8 0.24 11.3 6.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) XhlA PF10779.9 CDS33581.1 - 0.19 12.0 1.6 7.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Tho2 PF11262.8 CDS33581.1 - 0.83 8.8 4.6 2.5 7.2 0.8 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Snapin_Pallidin PF14712.6 CDS33581.1 - 1.8 9.1 7.0 15 6.0 3.5 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 CDS33581.1 - 4.2 7.9 6.4 2.7 8.5 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 PP-binding PF00550.25 CDS33582.1 - 3.9e-11 43.1 0.1 5.2e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CDS33582.1 - 6.4e-05 23.1 0.1 8.6e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier EF-hand_4 PF12763.7 CDS33583.1 - 7.3e-29 99.8 0.0 2.6e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CDS33583.1 - 7.9e-10 37.6 0.1 0.0049 16.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CDS33583.1 - 7.3e-08 31.8 0.9 0.057 13.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CDS33583.1 - 8.5e-08 32.5 0.8 0.037 14.5 0.0 3.5 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CDS33583.1 - 6.7e-05 22.7 0.7 0.16 11.8 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair ATG16 PF08614.11 CDS33583.1 - 0.012 15.8 14.4 0.012 15.8 14.4 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Sec5 PF15469.6 CDS33583.1 - 0.037 13.8 2.5 0.073 12.9 2.5 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 EF-hand_5 PF13202.6 CDS33583.1 - 0.076 12.6 0.5 13 5.5 0.0 2.4 2 0 0 2 2 2 0 EF hand AAA_13 PF13166.6 CDS33583.1 - 2.4 6.7 10.8 4.3 5.9 10.8 1.4 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.16 CDS33583.1 - 2.9 8.4 5.2 38 4.8 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 CSRNP_N PF16019.5 CDS33583.1 - 3 7.7 7.7 6.4 6.6 7.7 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Fib_alpha PF08702.10 CDS33583.1 - 3.6 7.8 5.9 4.8 7.4 4.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LUC7 PF03194.15 CDS33585.1 - 7.3e-73 245.3 9.5 7.3e-73 245.3 9.5 1.5 1 1 0 1 1 1 1 LUC7 N_terminus ST7 PF04184.12 CDS33585.1 - 0.018 13.5 2.7 0.026 13.0 2.7 1.1 1 0 0 1 1 1 0 ST7 protein Emaravirus_P4 PF16505.5 CDS33585.1 - 0.38 9.7 3.4 0.57 9.2 3.4 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Cbl_N PF02262.16 CDS33585.1 - 4.6 7.3 6.5 0.86 9.6 1.7 2.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Nbl1_Borealin_N PF10444.9 CDS33585.1 - 6 6.6 9.0 2.1 8.0 1.9 2.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Ribosomal_L21e PF01157.18 CDS33586.1 - 5.8e-46 154.5 6.6 8.6e-46 153.9 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Glyco_hydro_20 PF00728.22 CDS33587.1 - 6e-75 252.8 0.1 8e-75 252.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CDS33587.1 - 8.7e-11 42.6 0.0 1.9e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CDS33587.1 - 0.0021 18.9 0.0 0.011 16.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 CDS33587.1 - 0.027 14.6 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Tudor_FRX1 PF18336.1 CDS33587.1 - 0.41 10.6 2.8 0.26 11.2 0.2 2.0 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain Cys_Met_Meta_PP PF01053.20 CDS33589.1 - 3.1e-132 440.7 0.0 3.5e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CDS33589.1 - 8.8e-10 38.3 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 CDS33589.1 - 4.2e-07 28.8 0.0 8.1e-07 27.9 0.0 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CDS33589.1 - 4.9e-05 22.5 0.0 9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V CmcI PF04989.12 CDS33589.1 - 0.0039 16.9 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Cephalosporin hydroxylase DegT_DnrJ_EryC1 PF01041.17 CDS33589.1 - 0.066 12.5 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Auto_anti-p27 PF06677.12 CDS33590.1 - 2.9e-36 123.3 26.3 3e-15 56.1 1.1 4.3 4 0 0 4 4 4 3 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Carboxyl_trans PF01039.22 CDS33590.1 - 0.17 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain DUF3973 PF13119.6 CDS33590.1 - 0.56 10.3 6.1 3.5 7.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3973) zf-RVT PF13966.6 CDS33590.1 - 3.5 8.4 14.2 3 8.6 0.6 4.0 5 0 0 5 5 5 0 zinc-binding in reverse transcriptase Ephrin_rec_like PF07699.13 CDS33590.1 - 5.2 6.9 23.3 0.55 10.0 0.3 4.2 4 0 0 4 4 4 0 Putative ephrin-receptor like Pkinase PF00069.25 CDS33591.1 - 3.7e-59 200.2 0.0 4.9e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33591.1 - 7.2e-24 84.5 0.0 2.5e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CDS33591.1 - 0.1 12.0 0.2 0.27 10.6 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro-rich PF15240.6 CDS33591.1 - 0.6 10.4 34.2 0.8 10.0 34.2 1.1 1 0 0 1 1 1 0 Proline-rich WD40 PF00400.32 CDS33592.1 - 0.00041 21.1 16.3 0.3 12.0 0.0 6.2 7 1 0 7 7 7 2 WD domain, G-beta repeat Dynein_IC2 PF11540.8 CDS33592.1 - 0.16 12.0 0.6 0.53 10.3 0.6 2.0 1 1 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 LSM PF01423.22 CDS33593.1 - 1.3e-16 60.0 2.1 1.8e-16 59.5 2.1 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 CDS33593.1 - 0.018 14.9 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Phage_gp49_66 PF13876.6 CDS33593.1 - 0.02 15.2 0.3 0.093 13.0 0.1 1.9 1 1 1 2 2 2 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family Hfq PF17209.3 CDS33593.1 - 0.05 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 CDS33593.1 - 0.07 13.3 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain RT_RNaseH_2 PF17919.1 CDS33596.1 - 2.6e-27 94.8 0.5 9.8e-27 92.9 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS33596.1 - 3.6e-27 94.7 0.1 7.7e-27 93.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS33596.1 - 3.9e-24 85.4 0.0 7.4e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDS33596.1 - 1.1e-15 57.9 0.0 2.8e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS33596.1 - 3.6e-10 39.8 0.1 3.6e-10 39.8 0.1 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain LicD PF04991.13 CDS33598.1 - 4.1e-11 43.5 0.2 4.8e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 LicD family Aldo_ket_red PF00248.21 CDS33600.1 - 1.5e-48 165.5 0.0 3.4e-48 164.3 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family WW PF00397.26 CDS33601.1 - 2.9e-06 27.3 0.5 5.1e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 WW domain Cytochrom_B558a PF05038.13 CDS33601.1 - 0.046 13.3 0.3 0.081 12.5 0.3 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF4173 PF13777.6 CDS33602.1 - 0.02 14.4 0.5 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF2270 PF10028.9 CDS33602.1 - 0.21 11.1 0.7 0.41 10.2 0.3 1.7 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2270) Collagen PF01391.18 CDS33603.1 - 9.4e-164 531.3 658.8 8.4e-10 38.3 27.0 21.5 2 1 8 10 10 10 5 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CDS33603.1 - 3.4e-28 98.5 0.1 1e-21 77.3 0.0 2.1 2 0 0 2 2 2 2 Fibrillar collagen C-terminal domain Laminin_G_3 PF13385.6 CDS33603.1 - 0.002 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Homeodomain PF00046.29 CDS33604.1 - 4.4e-24 84.1 0.3 9.9e-24 83.0 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS33604.1 - 0.00026 20.8 0.3 0.00095 19.0 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain DSL PF01414.19 CDS33605.1 - 2.3e-08 34.2 1.2 2.3e-08 34.2 1.2 2.1 2 0 0 2 2 2 1 Delta serrate ligand EGF PF00008.27 CDS33605.1 - 0.0029 17.9 4.4 0.0029 17.9 4.4 2.9 3 1 0 3 3 3 1 EGF-like domain TMEM154 PF15102.6 CDS33605.1 - 0.024 14.6 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family CCSMST1 PF15013.6 CDS33605.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family zf-HIT PF04438.16 CDS33605.1 - 1.1 9.2 7.1 0.15 12.0 1.5 2.6 3 0 0 3 3 3 0 HIT zinc finger hEGF PF12661.7 CDS33605.1 - 7.6 7.3 13.0 0.4 11.4 1.8 4.0 4 0 0 4 4 4 0 Human growth factor-like EGF DUF5611 PF18446.1 CDS33608.1 - 0.054 14.4 0.2 3.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) fn3 PF00041.21 CDS33609.2 - 0.0018 18.5 0.2 0.039 14.3 0.0 2.7 3 0 0 3 3 3 1 Fibronectin type III domain DUF2369 PF10179.9 CDS33609.2 - 0.0091 16.4 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) ANTH PF07651.16 CDS33610.1 - 4e-54 183.5 1.5 5.4e-54 183.1 1.5 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CDS33610.1 - 5.1e-13 49.2 0.4 3.1e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 ENTH domain Patched PF02460.18 CDS33612.1 - 1.1e-68 232.2 28.0 4.9e-46 157.3 4.5 3.1 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CDS33612.1 - 7.4e-48 162.3 30.4 5.5e-29 101.0 1.6 3.9 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ADK PF00406.22 CDS33612.1 - 3.9e-36 124.4 0.0 6.4e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDS33612.1 - 5.2e-26 91.7 0.0 1.2e-25 90.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NPC1_N PF16414.5 CDS33612.1 - 3.4e-17 62.8 1.7 7.6e-17 61.7 1.7 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus AAA_18 PF13238.6 CDS33612.1 - 1.5e-06 28.8 0.0 3.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CDS33612.1 - 0.0047 16.7 1.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase MMPL PF03176.15 CDS33612.1 - 0.066 12.1 0.0 0.066 12.1 0.0 3.1 3 0 0 3 3 3 0 MMPL family AAA PF00004.29 CDS33612.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ACR_tran PF00873.19 CDS33612.1 - 5.9 4.4 11.4 10 3.6 11.4 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RRM_1 PF00076.22 CDS33613.1 - 2e-20 72.4 0.5 1.2e-11 44.3 0.4 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CDS33613.1 - 0.0062 16.3 0.0 0.021 14.6 0.1 1.9 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CDS33613.1 - 0.051 13.7 0.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif DUF961 PF06125.11 CDS33613.1 - 0.17 12.2 2.1 9.7 6.6 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF961) Patched PF02460.18 CDS33614.1 - 6.2e-70 236.3 10.0 3.4e-69 233.8 10.0 1.9 1 1 0 1 1 1 1 Patched family NPC1_N PF16414.5 CDS33614.1 - 7.2e-57 192.7 12.8 2.4e-56 191.0 12.8 1.9 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CDS33614.1 - 2e-48 164.1 23.8 9.6e-26 90.4 0.6 3.5 2 1 1 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation OAD_gamma PF04277.13 CDS33614.1 - 2.1 9.0 0.0 2.1 9.0 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MMPL PF03176.15 CDS33614.1 - 9 5.1 22.1 0.11 11.4 0.1 3.7 3 0 0 3 3 3 0 MMPL family Ank_2 PF12796.7 CDS33615.2 - 1.3e-142 464.8 29.4 4e-19 69.0 0.1 11.2 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.30 CDS33615.2 - 4.5e-128 412.7 56.4 5.1e-09 36.2 0.1 22.5 21 1 1 22 22 22 22 Ankyrin repeat Ank_4 PF13637.6 CDS33615.2 - 5.3e-126 409.5 46.1 2e-12 47.3 0.4 16.2 4 4 15 19 19 19 19 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS33615.2 - 1.5e-114 372.5 32.7 1.4e-10 41.2 0.5 15.2 4 3 9 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33615.2 - 9.9e-114 357.4 31.6 2.8e-06 27.2 0.0 22.8 23 0 0 23 23 23 21 Ankyrin repeat ZU5 PF00791.20 CDS33615.2 - 2.1e-28 98.5 0.1 2.6e-21 75.8 0.0 2.8 2 0 0 2 2 2 2 ZU5 domain UPA_2 PF17809.1 CDS33615.2 - 1.5e-23 83.0 0.0 2.4e-22 79.2 0.0 2.5 2 0 0 2 2 2 1 UPA domain Death PF00531.22 CDS33615.2 - 1e-07 32.0 0.0 3.2e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Death domain DUF1843 PF08898.10 CDS33615.2 - 0.036 14.6 0.0 8.9 6.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF2870 PF11069.8 CDS33617.1 - 3.1e-43 146.1 0.0 5.6e-43 145.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ubiquitin PF00240.23 CDS33617.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family TRAPPC-Trs85 PF12739.7 CDS33618.1 - 2.3e-84 283.7 0.8 3.2e-84 283.3 0.8 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit IMS PF00817.20 CDS33619.1 - 1.4e-41 141.9 0.1 3e-41 140.9 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 CDS33619.1 - 7.5e-13 47.8 0.3 1.5e-12 46.9 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 CDS33619.1 - 1e-06 29.4 0.0 2.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PRKCSH PF07915.13 CDS33619.1 - 0.15 13.0 0.3 0.81 10.7 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Metallophos PF00149.28 CDS33620.1 - 4.6e-30 105.6 0.7 6.9e-30 105.1 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDS33620.1 - 0.0096 16.3 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain 23S_rRNA_IVP PF05635.11 CDS33620.1 - 0.048 14.0 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Metallophos_2 PF12850.7 CDS33620.1 - 0.055 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Lebercilin PF15619.6 CDS33621.1 - 7.2e-18 64.9 31.5 7.2e-18 64.9 31.5 3.1 3 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 CDS33621.1 - 0.048 14.1 0.6 0.048 14.1 0.6 5.1 3 1 1 4 4 4 0 Cell division protein ZapB Exonuc_VIII PF06630.11 CDS33621.1 - 0.17 11.7 1.4 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII PRESAN PF09687.10 CDS33621.1 - 0.29 11.7 10.2 0.29 11.7 6.3 2.7 3 0 0 3 3 3 0 Plasmodium RESA N-terminal TPR_MLP1_2 PF07926.12 CDS33621.1 - 5.1 7.2 26.8 7.5 6.6 7.2 3.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 CDS33621.1 - 7.7 4.3 12.0 0.29 9.1 3.9 2.1 2 0 0 2 2 2 0 Prominin PKD_channel PF08016.12 CDS33622.1 - 5.3e-12 45.1 13.9 1e-11 44.2 13.9 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CDS33622.1 - 0.00034 19.9 23.6 0.002 17.4 23.5 2.0 1 1 0 1 1 1 1 Ion transport protein PIG-U PF06728.13 CDS33623.1 - 5.4e-42 144.2 27.6 7.4e-42 143.7 27.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Roc PF08477.13 CDS33623.1 - 3e-15 56.5 0.0 8.1e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS33623.1 - 3.6e-11 42.9 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CDS33623.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family TUG-UBL1 PF11470.8 CDS33624.1 - 2.4e-17 62.9 0.0 5.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 CDS33624.1 - 3.5e-06 27.1 0.0 0.00035 20.7 0.0 3.1 3 1 0 3 3 3 1 UBX domain SSF PF00474.17 CDS33626.1 - 3.8e-117 391.6 28.8 2.3e-116 389.0 28.8 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family RGS_DHEX PF18148.1 CDS33628.1 - 1.8e-35 121.0 0.5 6.5e-35 119.2 0.4 2.0 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 CDS33628.1 - 6.9e-25 87.6 0.2 3.7e-24 85.2 0.0 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 CDS33628.1 - 2.3e-12 46.8 0.1 9.2e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 CDS33628.1 - 0.00056 19.9 0.1 0.0024 17.8 0.1 2.1 2 0 0 2 2 2 1 GGL domain ABC_membrane PF00664.23 CDS33629.1 - 3.1e-34 118.9 18.5 5.3e-34 118.1 18.5 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDS33629.1 - 3.3e-34 118.3 0.0 5.8e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDS33629.1 - 5.1e-07 29.4 0.2 5.9e-05 22.6 0.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDS33629.1 - 0.0076 16.0 0.2 0.027 14.2 0.2 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CDS33629.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 CDS33629.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 CDS33629.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CDS33629.1 - 0.021 15.1 0.1 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDS33629.1 - 0.033 14.1 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 CDS33629.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Epiglycanin_C PF14654.6 CDS33629.1 - 3.1 7.9 6.5 14 5.8 0.7 3.2 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region SAM_decarbox PF01536.16 CDS33631.1 - 4.7e-92 308.7 0.2 5.4e-92 308.5 0.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase NDK PF00334.19 CDS33632.1 - 1.5e-63 212.8 0.0 1.7e-29 102.5 0.0 3.2 3 0 0 3 3 3 3 Nucleoside diphosphate kinase Androgen_recep PF02166.16 CDS33634.2 - 0.29 9.9 1.5 0.27 10.0 1.5 1.0 1 0 0 1 1 1 0 Androgen receptor DM PF00751.18 CDS33635.1 - 1.4e-29 101.7 30.4 6.7e-15 54.7 11.8 2.5 2 0 0 2 2 2 2 DM DNA binding domain zf-C3HC PF07967.13 CDS33635.1 - 0.065 13.3 3.8 0.078 13.0 0.5 2.3 2 0 0 2 2 2 0 C3HC zinc finger-like Anti-TRAP PF15777.5 CDS33635.1 - 1.1 9.2 3.8 9.7 6.2 1.3 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Fasciclin PF02469.22 CDS33636.1 - 1.5e-22 80.1 0.0 3.2e-10 40.3 0.0 4.3 4 1 0 4 4 4 3 Fasciclin domain LTV PF04180.14 CDS33637.1 - 2.2e-08 34.3 0.6 2.2e-08 34.3 0.6 3.3 2 2 1 3 3 3 1 Low temperature viability protein DUF4411 PF14367.6 CDS33637.1 - 0.1 12.5 0.4 0.29 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) F-box PF00646.33 CDS33638.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain Avl9 PF09794.9 CDS33639.1 - 1.6e-54 185.1 0.0 1.3e-37 129.4 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 CDS33639.1 - 7.8e-05 22.4 0.0 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CDS33639.1 - 0.0004 20.9 0.3 0.00081 19.9 0.0 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking UCH PF00443.29 CDS33641.1 - 1.4e-31 110.0 1.4 1.6e-31 109.7 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS33641.1 - 2.7e-17 63.3 3.6 2.2e-14 53.8 3.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ThiF PF00899.21 CDS33642.1 - 2.4e-104 348.0 0.0 3.2e-73 246.1 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CDS33642.1 - 7.9e-90 301.2 0.1 1.2e-89 300.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CDS33642.1 - 8.1e-33 113.0 0.1 1.9e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CDS33642.1 - 1.5e-32 111.6 0.0 3.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CDS33642.1 - 2.3e-21 75.8 1.2 1.1e-20 73.6 0.7 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle 4F5 PF04419.14 CDS33643.1 - 0.00061 20.6 10.2 0.00061 20.6 10.2 2.7 2 1 0 2 2 2 1 4F5 protein family DUF4974 PF16344.5 CDS33645.2 - 0.041 13.9 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Ad_cyc_g-alpha PF08509.11 CDS33645.2 - 0.045 13.5 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain Sporozoite_P67 PF05642.11 CDS33645.2 - 1.9 6.5 7.7 4 5.4 7.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Carn_acyltransf PF00755.20 CDS33646.1 - 1.3e-98 331.2 0.2 1.5e-98 331.0 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF5370 PF17340.2 CDS33646.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5370) DUF1500 PF07389.12 CDS33646.1 - 0.094 12.8 0.2 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1500) FAM86 PF14904.6 CDS33646.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function Mito_carr PF00153.27 CDS33647.1 - 7.6e-35 118.7 0.0 3.1e-16 59.1 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein WBS_methylT PF12589.8 CDS33648.1 - 5.1e-15 56.0 1.5 8.5e-15 55.3 1.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CDS33648.1 - 2.8e-11 43.9 0.0 7.9e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS33648.1 - 1.3e-10 41.8 0.0 4.7e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS33648.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS33648.1 - 4.8e-05 24.0 0.0 0.00021 22.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS33648.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 CDS33648.1 - 0.0019 18.0 0.0 0.01 15.6 0.0 2.0 2 1 0 2 2 2 1 DNA methylase Methyltransf_32 PF13679.6 CDS33648.1 - 0.042 13.8 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CDS33648.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase SKI PF01202.22 CDS33649.1 - 7.7e-09 35.9 0.0 8.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 CDS33649.1 - 1.3e-08 35.4 0.0 3.5e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDS33649.1 - 6.4e-07 29.6 0.0 9.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDS33649.1 - 7.1e-05 23.3 0.0 0.042 14.3 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CDS33649.1 - 0.00016 22.2 0.0 0.00016 22.2 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CDS33649.1 - 0.00025 21.5 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDS33649.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDS33649.1 - 0.0019 18.5 0.0 0.0029 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDS33649.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CDS33649.1 - 0.0068 16.3 0.0 0.24 11.2 0.0 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase Rad17 PF03215.15 CDS33649.1 - 0.0074 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain APS_kinase PF01583.20 CDS33649.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PduV-EutP PF10662.9 CDS33649.1 - 0.009 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CDS33649.1 - 0.01 15.7 0.4 0.097 12.6 0.0 2.3 1 1 2 3 3 3 0 NACHT domain RsgA_GTPase PF03193.16 CDS33649.1 - 0.012 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase tRNA_lig_kinase PF08303.11 CDS33649.1 - 0.013 15.6 0.1 0.058 13.5 0.1 2.0 2 1 1 3 3 3 0 tRNA ligase kinase domain AAA_28 PF13521.6 CDS33649.1 - 0.014 15.7 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CDS33649.1 - 0.014 15.5 0.2 0.12 12.5 0.2 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 CDS33649.1 - 0.015 15.8 0.1 0.023 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDS33649.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS33649.1 - 0.022 14.5 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CDS33649.1 - 0.039 13.8 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 CDS33649.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activat PF00158.26 CDS33649.1 - 0.049 13.3 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDS33649.1 - 0.055 12.9 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDS33649.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 CDS33649.1 - 0.06 13.1 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 CDS33649.1 - 0.09 12.5 0.0 14 5.3 0.0 2.1 1 1 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.6 CDS33649.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain HECT PF00632.25 CDS33650.1 - 2.1e-95 319.8 0.7 5.2e-95 318.5 0.7 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 CDS33650.1 - 3.1e-82 276.5 2.7 6.7e-82 275.4 0.0 2.9 2 1 0 2 2 2 1 Domain of Unknown Function (DUF913) UBM PF14377.6 CDS33650.1 - 2.3e-22 77.7 11.8 1.5e-09 37.0 0.4 3.9 3 0 0 3 3 3 3 Ubiquitin binding region DUF908 PF06012.12 CDS33650.1 - 4.4e-18 65.8 12.2 4.3e-12 46.1 0.1 4.4 3 1 1 4 4 4 2 Domain of Unknown Function (DUF908) MgtE_N PF03448.17 CDS33650.1 - 0.033 14.8 5.1 0.19 12.4 3.0 3.2 2 1 1 3 3 3 0 MgtE intracellular N domain UK PF02512.14 CDS33650.1 - 0.092 13.3 0.4 13 6.4 0.0 3.3 3 0 0 3 3 3 0 Virulence determinant Cpn60_TCP1 PF00118.24 CDS33651.2 - 1.4e-125 419.7 0.1 1.8e-125 419.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-DNL PF05180.12 CDS33652.1 - 1.6e-21 76.0 0.3 3.6e-21 74.9 0.3 1.6 1 0 0 1 1 1 1 DNL zinc finger zf-RING_2 PF13639.6 CDS33652.1 - 3.8e-10 39.9 8.1 3.8e-10 39.9 8.1 2.6 2 1 0 2 2 1 1 Ring finger domain TRC8_N PF13705.6 CDS33652.1 - 1.3e-09 37.5 11.5 1.3e-09 37.5 11.5 3.4 2 1 0 2 2 2 1 TRC8 N-terminal domain zf-rbx1 PF12678.7 CDS33652.1 - 2.4e-08 34.1 5.4 2.4e-08 34.1 5.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDS33652.1 - 3e-07 30.1 8.6 3e-07 30.1 8.6 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS33652.1 - 1e-05 25.5 6.1 3.3e-05 23.8 6.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CDS33652.1 - 1.1e-05 25.0 4.1 3.3e-05 23.5 4.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDS33652.1 - 1.2e-05 25.1 7.1 1.2e-05 25.1 7.1 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS33652.1 - 0.0016 18.2 5.0 0.0016 18.2 5.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS33652.1 - 0.0038 17.1 6.9 0.0038 17.1 6.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDS33652.1 - 0.008 16.2 3.5 0.01 15.8 2.1 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Endonuclease_7 PF02945.15 CDS33652.1 - 0.019 14.9 0.6 0.019 14.9 0.6 1.9 2 0 0 2 2 2 0 Recombination endonuclease VII DUF35_N PF12172.8 CDS33652.1 - 0.12 12.3 0.8 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FANCL_C PF11793.8 CDS33652.1 - 1.8 8.8 10.7 0.25 11.5 5.2 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain RINGv PF12906.7 CDS33652.1 - 1.9 8.7 6.4 5.6 7.2 6.4 1.8 1 0 0 1 1 1 0 RING-variant domain DUF3039 PF11238.8 CDS33652.1 - 3.6 7.4 4.9 0.56 10.0 0.5 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3039) zf-C3H2C3 PF17122.5 CDS33652.1 - 4.7 7.3 8.9 0.13 12.4 1.7 2.2 2 0 0 2 2 1 0 Zinc-finger TBCA PF02970.16 CDS33653.1 - 1.4e-22 79.8 3.9 1.8e-22 79.4 3.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A FapA PF03961.13 CDS33653.1 - 0.016 13.8 0.4 0.019 13.6 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF155 PF02582.14 CDS33654.1 - 5e-36 124.4 1.1 1.3e-35 123.1 0.3 2.1 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Metallophos PF00149.28 CDS33654.1 - 7.6e-13 49.4 0.0 1.2e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDS33654.1 - 0.054 13.7 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Topoisom_bac PF01131.20 CDS33655.1 - 6.1e-104 348.3 0.0 7.7e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CDS33655.1 - 5.4e-18 65.1 0.0 9.1e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Ldl_recept_a PF00057.18 CDS33657.1 - 1.8e-07 31.2 9.2 3.5e-07 30.3 9.2 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Ion_trans PF00520.31 CDS33657.1 - 0.048 12.9 0.2 0.098 11.9 0.2 1.4 1 0 0 1 1 1 0 Ion transport protein PepSY_TM PF03929.16 CDS33657.1 - 0.091 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 PepSY-associated TM region EphA2_TM PF14575.6 CDS33657.1 - 0.11 13.3 0.0 0.34 11.8 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMF_DNA_bd PF12329.8 CDS33658.1 - 0.0002 21.3 0.9 0.00058 19.8 0.9 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Med9 PF07544.13 CDS33658.1 - 2.3 8.4 9.0 1.1 9.4 1.7 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Neur_chan_memb PF02932.16 CDS33659.1 - 2.6e-61 207.7 1.5 3.4e-61 207.3 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CDS33659.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Guanylate_kin PF00625.21 CDS33662.1 - 3.5e-44 150.7 1.0 6.8e-44 149.7 1.0 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 CDS33662.1 - 0.011 15.3 0.2 0.034 13.8 0.1 1.9 2 0 0 2 2 2 0 SH3 domain ImpA_N PF06812.12 CDS33662.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system VGCC_beta4Aa_N PF12052.8 CDS33662.1 - 0.4 10.8 11.0 22 5.2 11.0 3.1 1 1 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Peptidase_C2 PF00648.21 CDS33663.2 - 8.6e-107 356.6 0.0 1.5e-106 355.8 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDS33663.2 - 9.6e-44 149.1 0.0 2e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.32 CDS33663.2 - 7.8e-06 25.1 0.2 0.23 11.1 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CDS33663.2 - 2e-05 24.3 4.1 3.3e-05 23.6 0.2 3.5 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS33663.2 - 0.00065 19.4 0.1 3.3 7.9 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CDS33663.2 - 0.00078 19.9 2.9 0.86 10.1 0.5 3.4 3 0 0 3 3 3 2 EF-hand domain pair Phosphodiest PF01663.22 CDS33667.2 - 2e-61 208.6 0.2 2.5e-61 208.3 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 CDS33667.2 - 2.9e-05 24.3 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 PglZ domain Metalloenzyme PF01676.18 CDS33667.2 - 0.00039 19.9 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDS33667.2 - 0.0068 15.8 0.0 0.11 11.9 0.0 2.2 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CDS33668.2 - 3.3e-59 201.3 0.3 3.9e-59 201.0 0.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CDS33668.2 - 0.00025 20.5 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDS33668.2 - 0.0021 17.5 0.0 0.1 12.0 0.0 2.4 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 CDS33668.2 - 0.057 13.5 0.0 0.48 10.5 0.0 2.5 3 1 0 3 3 3 0 PglZ domain EMP70 PF02990.16 CDS33669.1 - 0.044 12.5 6.7 0.051 12.2 6.7 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 MARVEL PF01284.23 CDS33669.1 - 0.072 13.1 24.7 0.55 10.3 24.7 2.1 1 1 0 1 1 1 0 Membrane-associating domain DUF4658 PF15555.6 CDS33669.1 - 0.72 10.0 4.5 2.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) DHHC PF01529.20 CDS33669.1 - 0.9 9.6 16.3 5.8 7.0 16.3 1.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase EF-hand_1 PF00036.32 CDS33670.1 - 3e-26 89.0 22.1 7.9e-07 28.2 1.2 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.6 CDS33670.1 - 5.7e-24 82.0 20.9 2.1e-06 27.2 0.3 6.7 6 0 0 6 6 6 6 EF-hand domain EF-hand_7 PF13499.6 CDS33670.1 - 1.2e-20 73.7 27.6 1.7e-09 38.0 1.7 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS33670.1 - 4.4e-10 38.6 19.5 0.0033 16.9 0.3 6.6 6 0 0 6 6 6 4 EF hand GPHH PF16905.5 CDS33670.1 - 9.7e-05 22.1 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 2 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_9 PF14658.6 CDS33670.1 - 0.022 15.1 1.8 0.28 11.5 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain EF-hand_13 PF17958.1 CDS33670.1 - 0.027 14.3 0.1 5.1 7.0 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain MOSC_N PF03476.16 CDS33670.1 - 0.039 13.8 0.2 42 4.1 0.0 3.2 3 0 0 3 3 3 0 MOSC N-terminal beta barrel domain SWIRM PF04433.17 CDS33670.1 - 0.044 14.1 0.5 0.58 10.5 0.3 2.5 1 1 1 2 2 2 0 SWIRM domain EF-hand_8 PF13833.6 CDS33670.1 - 0.056 13.3 20.9 0.089 12.7 0.6 5.7 6 0 0 6 6 6 0 EF-hand domain pair EF-hand_10 PF14788.6 CDS33670.1 - 0.17 11.8 14.9 3.1 7.7 0.0 5.1 6 0 0 6 6 6 0 EF hand SPARC_Ca_bdg PF10591.9 CDS33670.1 - 0.28 11.5 15.7 3.2 8.1 0.1 4.4 1 1 3 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region RhoGAP PF00620.27 CDS33670.1 - 0.46 10.3 3.5 0.5 10.2 0.8 2.3 3 0 0 3 3 3 0 RhoGAP domain Ribonuc_red_2_N PF08471.10 CDS33670.1 - 0.64 10.2 3.1 44 4.3 0.0 3.5 4 0 0 4 4 4 0 Class II vitamin B12-dependent ribonucleotide reductase Caleosin PF05042.13 CDS33670.1 - 3.5 7.5 11.0 43 4.0 0.1 4.5 4 1 1 5 5 5 0 Caleosin related protein BRF1 PF07741.13 CDS33671.1 - 0.71 10.2 7.7 1.6 9.1 7.7 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SSF PF00474.17 CDS33672.1 - 6.7e-27 94.4 27.5 1.1e-26 93.7 27.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family TPR_8 PF13181.6 CDS33675.1 - 9.3e-30 100.3 12.8 0.0022 18.1 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 CDS33675.1 - 2.5e-29 99.9 13.6 8.2e-06 25.4 0.2 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 CDS33675.1 - 3.8e-27 94.6 8.7 4.1e-07 30.5 0.0 6.3 4 2 3 7 7 7 5 Tetratricopeptide repeat DUF1736 PF08409.11 CDS33675.1 - 6.2e-27 93.4 2.3 1.1e-26 92.6 1.0 2.2 2 0 0 2 2 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 CDS33675.1 - 1.5e-25 87.2 20.3 2.1e-05 24.3 0.3 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDS33675.1 - 4.9e-22 78.0 19.0 3.1e-05 24.2 0.0 6.9 2 1 6 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 CDS33675.1 - 9.5e-22 77.3 11.3 2.1e-05 25.0 0.6 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDS33675.1 - 7.9e-21 73.5 19.4 0.00012 21.7 0.1 9.3 6 2 4 10 10 10 5 TPR repeat TPR_14 PF13428.6 CDS33675.1 - 3.5e-18 64.7 13.1 0.1 13.5 0.1 8.6 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 CDS33675.1 - 5.2e-14 51.2 18.9 0.04 14.0 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS33675.1 - 1.4e-11 43.9 19.6 0.076 13.4 0.0 10.0 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS33675.1 - 8.9e-10 38.6 14.5 0.58 10.9 0.0 8.7 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDS33675.1 - 4.7e-08 33.1 5.7 0.023 14.8 0.3 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDS33675.1 - 9.5e-08 31.7 23.5 0.1 12.5 0.3 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS33675.1 - 6.7e-06 26.2 16.9 0.059 13.6 1.1 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 CDS33675.1 - 5.4e-05 22.7 2.3 0.00043 19.8 1.3 2.7 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_4 PF07721.14 CDS33675.1 - 0.00078 19.8 4.9 16 6.5 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 CDS33675.1 - 0.0017 17.4 11.1 1.3 7.9 9.3 3.9 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TOM20_plant PF06552.12 CDS33675.1 - 0.0021 17.9 0.0 0.8 9.4 0.0 2.9 3 0 0 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 PMT_2 PF13231.6 CDS33675.1 - 0.01 16.0 11.5 0.01 16.0 11.5 2.4 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_21 PF09976.9 CDS33675.1 - 0.52 10.0 8.8 0.36 10.5 1.2 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 CDS33675.1 - 0.72 10.2 7.9 6.3 7.2 0.0 4.8 3 1 2 6 6 6 0 Tetratricopeptide repeat MT-A70 PF05063.14 CDS33676.1 - 9.4e-59 198.2 0.0 1.5e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 MT-A70 WD40 PF00400.32 CDS33677.1 - 2.9e-19 69.0 9.4 8.5e-05 23.2 0.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS33677.1 - 1.3e-07 31.8 0.0 0.31 11.4 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDS33677.1 - 7.7e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 CDS33677.1 - 0.011 14.4 0.0 0.29 9.7 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TSSC4 PF15264.6 CDS33678.1 - 2.7e-07 30.9 0.6 2.7e-07 30.9 0.6 1.9 2 0 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 PV-1 PF06637.11 CDS33678.1 - 0.13 11.1 1.1 0.19 10.5 1.1 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Aminotran_1_2 PF00155.21 CDS33679.1 - 1.6e-90 303.9 0.0 1.9e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 CDS33681.1 - 5.7e-15 54.8 25.3 0.00094 19.5 1.8 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33681.1 - 3.6e-12 46.0 24.8 0.0095 16.7 0.2 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS33681.1 - 8.5e-07 29.1 25.6 9.8e-05 22.6 0.5 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CDS33681.1 - 2.4e-05 24.5 11.1 2.9 8.3 2.5 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDS33681.1 - 0.0016 18.7 4.0 0.0016 18.7 4.0 3.3 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CDS33681.1 - 0.012 15.7 20.5 0.21 11.6 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2256 PF10013.9 CDS33681.1 - 0.013 15.6 8.0 2.9 8.1 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 CDS33681.1 - 0.041 14.6 15.2 0.4 11.4 0.2 3.8 2 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CDS33681.1 - 0.11 12.9 16.5 1.2 9.6 3.5 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDS33681.1 - 0.21 11.4 0.1 0.21 11.4 0.1 3.5 4 0 0 4 4 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CDS33681.1 - 0.24 11.5 15.5 0.12 12.5 3.9 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 CDS33681.1 - 0.28 12.0 11.3 3.6 8.4 2.4 2.6 2 0 0 2 2 2 0 zinc-ribbon family FOXP-CC PF16159.5 CDS33681.1 - 0.38 11.4 8.5 18 6.0 0.2 3.7 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2039 PF10217.9 CDS33681.1 - 0.48 10.8 11.2 1.7 9.0 3.5 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Arc_trans_TRASH PF08394.10 CDS33681.1 - 0.66 10.4 4.9 13 6.3 0.7 3.3 2 2 0 2 2 2 0 Archaeal TRASH domain zf_UBZ PF18439.1 CDS33681.1 - 0.68 9.6 11.5 4.4 7.0 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 CDS33681.1 - 0.91 9.5 13.9 0.5 10.3 0.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 CDS33681.1 - 2.5 8.6 7.5 4.2 7.9 0.0 3.7 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 CDS33681.1 - 6.4 6.7 11.4 8.1 6.4 0.3 4.1 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 CDS33681.1 - 8.3 6.1 6.0 6.7 6.4 0.1 3.2 3 1 0 3 3 3 0 MYST family zinc finger domain DZR PF12773.7 CDS33681.1 - 9.8 6.3 14.1 6.5e+02 0.5 14.1 2.9 1 1 0 1 1 1 0 Double zinc ribbon DUF3524 PF12038.8 CDS33682.1 - 1.9e-59 200.3 0.0 3e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Snf7 PF03357.21 CDS33682.1 - 1.7e-36 125.4 15.9 2.4e-36 124.9 15.9 1.2 1 0 0 1 1 1 1 Snf7 Glycos_transf_1 PF00534.20 CDS33682.1 - 3.8e-06 26.6 0.1 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 N2227 PF07942.12 CDS33683.1 - 7.4e-99 330.3 0.0 1.2e-98 329.7 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 CDS33683.1 - 0.0075 16.9 0.0 0.064 13.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS33683.1 - 0.01 15.7 0.0 0.04 13.7 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDS33683.1 - 0.065 14.0 0.0 0.37 11.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cullin_Nedd8 PF10557.9 CDS33683.1 - 0.27 11.3 0.9 0.69 10.0 0.3 2.0 2 0 0 2 2 2 0 Cullin protein neddylation domain PCMT PF01135.19 CDS33684.1 - 1.8e-70 237.0 0.0 2.1e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CDS33684.1 - 0.00047 19.6 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CDS33684.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS33684.1 - 0.0061 16.4 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS33684.1 - 0.0082 16.8 0.0 0.026 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CDS33684.1 - 0.01 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase GCD14 PF08704.10 CDS33684.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 CDS33684.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Fibrillarin PF01269.17 CDS33684.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_11 PF08241.12 CDS33684.1 - 0.12 13.0 0.0 0.59 10.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CDS33684.1 - 0.22 10.8 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_M17 PF00883.21 CDS33685.1 - 1e-97 327.2 0.0 3.6e-97 325.4 0.0 1.8 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CDS33685.1 - 2.8e-06 27.2 0.1 7.9e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain HMG_box_2 PF09011.10 CDS33685.1 - 0.013 16.0 2.9 0.014 16.0 0.2 2.2 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 CDS33685.1 - 0.072 13.5 1.5 0.23 11.9 1.5 1.9 1 1 0 1 1 1 0 HMG (high mobility group) box Y_phosphatase PF00102.27 CDS33686.1 - 9.8e-121 401.7 0.4 2.1e-41 142.1 0.0 4.2 4 0 0 4 4 4 4 Protein-tyrosine phosphatase fn3 PF00041.21 CDS33686.1 - 1.6e-38 130.9 27.6 6.4e-11 42.4 0.1 12.5 12 1 0 12 12 12 7 Fibronectin type III domain I-set PF07679.16 CDS33686.1 - 3.9e-36 123.0 0.0 7.5e-14 51.6 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS33686.1 - 9.2e-35 119.1 1.9 2.3e-11 44.1 0.0 6.4 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 CDS33686.1 - 6.2e-19 68.1 0.0 3e-08 33.9 0.0 4.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CDS33686.1 - 2.8e-12 46.7 0.0 0.00029 20.9 0.0 4.3 3 0 0 3 3 3 3 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CDS33686.1 - 3e-08 34.1 6.1 0.98 10.0 0.0 6.2 6 0 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain DSPc PF00782.20 CDS33686.1 - 0.0003 20.6 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDS33686.1 - 0.00076 19.5 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family ASH PF15780.5 CDS33686.1 - 0.0017 18.5 0.1 6.5 7.0 0.0 3.7 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin V-set PF07686.17 CDS33686.1 - 0.0033 17.6 0.5 0.66 10.2 0.0 4.0 3 1 0 3 3 3 1 Immunoglobulin V-set domain fn3_4 PF16794.5 CDS33686.1 - 0.0067 16.3 0.0 9.3 6.2 0.0 3.2 3 0 0 3 3 3 2 Fibronectin-III type domain Ig_4 PF16680.5 CDS33686.1 - 0.035 14.4 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain PTPlike_phytase PF14566.6 CDS33686.1 - 0.14 12.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Dyp_perox PF04261.12 CDS33687.1 - 9.6e-45 153.0 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family F-box-like PF12937.7 CDS33688.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDS33688.1 - 0.024 14.5 0.2 0.06 13.3 0.2 1.7 1 0 0 1 1 1 0 F-box domain XendoU PF09412.10 CDS33689.1 - 9e-70 234.9 0.0 1.2e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Mycobact_memb PF05423.13 CDS33689.1 - 0.047 13.6 0.1 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Mycobacterium membrane protein DUF3395 PF11875.8 CDS33689.1 - 0.17 11.8 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) MAPKK1_Int PF08923.10 CDS33690.1 - 3.4e-13 49.4 0.0 4.8e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting WD40 PF00400.32 CDS33691.1 - 4e-44 147.7 28.5 2e-08 34.7 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS33691.1 - 9.6e-10 38.6 0.2 0.24 11.7 0.0 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS33691.1 - 6.1e-05 21.9 5.4 0.01 14.5 0.0 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDS33691.1 - 0.0038 16.6 0.0 0.89 8.8 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain DUF1513 PF07433.11 CDS33691.1 - 0.038 13.1 0.1 3.5 6.6 0.0 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1513) Laminin_EGF PF00053.24 CDS33692.1 - 4.7e-113 369.2 350.9 8e-10 38.7 12.3 20.0 18 2 2 20 20 20 18 Laminin EGF domain Laminin_N PF00055.17 CDS33692.1 - 1.2e-59 201.7 0.0 1.2e-59 201.7 0.0 2.6 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 CDS33692.1 - 3.5e-21 75.5 0.9 3.2e-18 65.9 0.4 3.0 2 1 0 2 2 2 2 Laminin B (Domain IV) IFT57 PF10498.9 CDS33692.1 - 0.31 10.0 12.1 0.015 14.3 3.5 2.4 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 zf-C3HC4_2 PF13923.6 CDS33693.1 - 1.3e-08 34.5 2.7 3.5e-08 33.1 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS33693.1 - 8.6e-07 28.7 4.2 8.6e-07 28.7 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS33693.1 - 3e-06 27.5 2.5 3e-06 27.5 2.5 2.3 2 0 0 2 2 2 1 Ring finger domain RAWUL PF16207.5 CDS33693.1 - 5.7e-05 23.7 0.0 0.00025 21.7 0.0 2.1 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_UBOX PF13445.6 CDS33693.1 - 6e-05 23.0 0.4 0.00017 21.5 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDS33693.1 - 8.1e-05 22.5 3.8 0.00019 21.3 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS33693.1 - 0.00012 21.8 3.4 0.00033 20.5 3.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDS33693.1 - 0.00032 20.9 1.2 0.00032 20.9 1.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDS33693.1 - 0.00085 19.1 3.5 0.00085 19.1 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDS33693.1 - 0.077 13.2 6.3 0.46 10.7 6.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDS33693.1 - 0.28 11.0 7.0 0.14 12.0 2.9 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CDS33693.1 - 0.77 9.8 3.8 2.1 8.5 3.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon IQ PF00612.27 CDS33695.1 - 1e-06 28.0 0.4 1e-06 28.0 0.4 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif CTP_transf_1 PF01148.20 CDS33696.2 - 4.1e-64 216.9 14.5 9.4e-62 209.2 11.2 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family PFK PF00365.20 CDS33697.1 - 1.6e-200 664.2 5.9 3.6e-111 371.0 1.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase RhoGAP PF00620.27 CDS33698.2 - 5.1e-35 120.5 0.0 1.9e-34 118.7 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 CDS33698.2 - 3.8e-05 23.4 0.3 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 BAR domain DUF737 PF05300.11 CDS33698.2 - 0.21 11.9 8.4 1.3 9.3 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Dynamin_M PF01031.20 CDS33699.1 - 4.8e-101 337.7 0.1 1.1e-100 336.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDS33699.1 - 5.1e-54 182.8 0.5 2.4e-53 180.6 0.0 2.2 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 CDS33699.1 - 1.5e-25 89.2 2.5 4.7e-25 87.6 2.5 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDS33699.1 - 0.00019 21.5 0.1 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDS33699.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Baculo_PEP_C PF04513.12 CDS33699.1 - 0.02 14.9 1.7 0.2 11.7 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Roc PF08477.13 CDS33699.1 - 0.084 13.1 0.0 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Androgen_recep PF02166.16 CDS33699.1 - 1.1 8.0 6.1 1.7 7.4 6.1 1.1 1 0 0 1 1 1 0 Androgen receptor zf-C2H2_4 PF13894.6 CDS33700.1 - 0.0012 19.5 47.2 0.22 12.5 0.3 8.8 8 0 0 8 8 8 2 C2H2-type zinc finger zf_ZIC PF18366.1 CDS33700.1 - 0.034 14.2 2.2 1.1 9.4 0.2 2.8 2 0 0 2 2 2 0 Zic proteins zinc finger domain DNA_primase_lrg PF04104.14 CDS33700.1 - 0.11 11.9 8.1 0.035 13.5 1.6 2.8 3 0 0 3 3 3 0 Eukaryotic and archaeal DNA primase, large subunit zf-C2H2 PF00096.26 CDS33700.1 - 0.18 12.3 0.1 0.037 14.5 4.2 8.3 8 0 0 8 8 8 0 Zinc finger, C2H2 type DUF2024 PF09630.10 CDS33700.1 - 5.5 6.9 8.7 3.1 7.7 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) zf-C2H2_8 PF15909.5 CDS33700.1 - 8.3 6.8 13.4 4 7.8 0.8 3.8 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-CCCH PF00642.24 CDS33701.2 - 3.8e-08 33.0 15.7 0.0019 18.0 0.1 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS33701.2 - 7.8e-05 22.6 1.7 7.8e-05 22.6 1.7 4.2 5 0 0 5 5 5 1 Zinc finger domain Torus PF16131.5 CDS33701.2 - 0.0069 17.1 11.3 0.068 13.9 0.7 3.4 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CDS33701.2 - 0.017 15.3 8.8 1.3 9.3 2.4 2.9 2 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDS33701.2 - 0.02 14.7 0.3 0.02 14.7 0.3 4.1 4 0 0 4 4 4 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDS33702.1 - 0.00044 20.2 4.3 0.00044 20.2 4.3 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 CDS33702.1 - 0.00063 19.9 3.2 0.037 14.2 3.6 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH PF00642.24 CDS33702.1 - 0.0017 18.2 1.1 0.0017 18.2 1.1 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.16 CDS33702.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 CUE domain Torus PF16131.5 CDS33702.1 - 0.13 13.0 5.7 1.6 9.5 0.7 2.7 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 CDS33702.1 - 2.5 8.7 9.5 0.094 13.2 1.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger HSP20 PF00011.21 CDS33704.1 - 4.3e-24 84.6 0.1 1.3e-13 50.9 0.0 3.3 2 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDS33704.1 - 1.9e-11 43.3 0.1 6e-05 22.5 0.0 2.4 2 1 0 2 2 2 2 HSP20-like domain found in ArsA CS PF04969.16 CDS33704.1 - 0.012 16.6 0.0 5.6 8.1 0.0 2.4 2 0 0 2 2 2 0 CS domain BON PF04972.17 CDS33704.1 - 0.15 12.4 0.1 29 5.1 0.0 3.3 4 0 0 4 4 4 0 BON domain PKcGMP_CC PF16808.5 CDS33704.1 - 3.2 7.7 4.9 10 6.1 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HSP20 PF00011.21 CDS33705.1 - 2.7e-24 85.3 0.0 8.1e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDS33705.1 - 1.9e-08 33.7 0.0 3.4e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Laminin_G_2 PF02210.24 CDS33707.2 - 1e-63 213.6 2.3 1.8e-15 57.6 0.0 6.0 6 0 0 6 6 6 5 Laminin G domain Laminin_G_1 PF00054.23 CDS33707.2 - 8.2e-44 149.0 0.1 7.5e-11 42.4 0.0 6.2 6 0 0 6 6 6 4 Laminin G domain Laminin_G_3 PF13385.6 CDS33707.2 - 2.5e-06 27.7 0.1 0.96 9.6 0.0 4.9 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.20 CDS33707.2 - 0.00025 20.9 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain EGF PF00008.27 CDS33707.2 - 0.38 11.1 17.7 1.1 9.7 4.2 2.6 2 0 0 2 2 2 0 EGF-like domain Ldl_recept_a PF00057.18 CDS33707.2 - 0.9 9.8 4.9 3.1 8.1 4.9 2.0 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A CoatB PF10389.9 CDS33707.2 - 1.1 9.2 2.5 1.8 8.5 0.5 2.1 2 0 0 2 2 2 0 Bacteriophage coat protein B Laminin_G_2 PF02210.24 CDS33708.1 - 5.2e-08 33.5 0.0 7.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CDS33708.1 - 3.7e-06 27.2 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain P-mevalo_kinase PF04275.14 CDS33709.1 - 1.5e-40 137.7 0.1 2.2e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Phosphomevalonate kinase RRM_1 PF00076.22 CDS33711.1 - 2.7e-09 36.7 0.0 3.8e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.13 CDS33711.1 - 1.3e-05 23.6 41.2 1.3e-05 23.6 41.2 3.9 3 1 0 3 3 3 1 DNA polymerase phi DNA_pol_E_B PF04042.16 CDS33712.1 - 3.7e-21 75.5 0.1 5.3e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B zf-C2H2 PF00096.26 CDS33713.1 - 0.0011 19.3 3.1 0.0023 18.3 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33713.1 - 0.011 16.5 3.1 0.022 15.5 3.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS33713.1 - 0.017 15.6 0.8 0.017 15.6 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double domain GAGA PF09237.11 CDS33713.1 - 0.025 14.4 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 GAGA factor zf-C2H2_11 PF16622.5 CDS33713.1 - 0.037 13.8 0.1 0.095 12.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2HE PF16278.5 CDS33713.1 - 0.042 14.3 0.5 0.042 14.3 0.5 1.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 CDS33713.1 - 0.059 13.5 2.6 0.094 12.9 2.6 1.3 1 0 0 1 1 1 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 CDS33713.1 - 0.15 12.1 4.1 0.25 11.4 4.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Med31 PF05669.12 CDS33714.1 - 3.9e-36 122.9 3.1 5.1e-36 122.6 3.1 1.1 1 0 0 1 1 1 1 SOH1 Glyco_transf_43 PF03360.16 CDS33716.1 - 3.5e-62 209.9 0.0 5.8e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 43 Gelsolin PF00626.22 CDS33719.2 - 3.3e-42 142.2 0.8 1.2e-09 37.9 0.0 6.8 6 1 0 6 6 6 5 Gelsolin repeat LRR_8 PF13855.6 CDS33719.2 - 1.3e-37 127.4 42.4 1.4e-10 40.7 4.2 7.1 3 1 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CDS33719.2 - 2.7e-33 113.4 53.6 3.3e-06 27.3 2.7 9.1 6 2 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS33719.2 - 4.4e-06 26.5 48.5 3 8.7 0.5 14.8 15 1 0 15 15 15 1 Leucine Rich Repeat LRR_9 PF14580.6 CDS33719.2 - 9.5e-06 25.2 18.7 0.56 9.7 1.4 4.4 1 1 2 4 4 4 4 Leucine-rich repeat DUF1835 PF08874.10 CDS33719.2 - 0.0033 17.6 0.1 8 6.7 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1835) LRR_5 PF13306.6 CDS33719.2 - 0.0048 16.9 0.2 0.14 12.1 0.0 2.8 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CDS33719.2 - 0.047 13.8 43.2 3.4 8.0 0.1 11.0 12 0 0 12 12 12 0 Leucine Rich repeat MerR-DNA-bind PF09278.11 CDS33719.2 - 0.12 12.9 0.2 0.83 10.2 0.0 2.6 2 0 0 2 2 2 0 MerR, DNA binding GRIP PF01465.20 CDS33720.2 - 2.1e-12 46.7 0.2 6.3e-12 45.2 0.2 1.9 1 0 0 1 1 1 1 GRIP domain KASH_CCD PF14662.6 CDS33720.2 - 1.4e-06 28.3 29.7 1.4e-06 28.3 29.7 9.5 1 1 7 9 9 9 2 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 CDS33720.2 - 0.0076 15.9 21.7 0.0076 15.9 21.7 9.9 1 1 7 8 8 8 2 Intermediate filament protein kleA_kleC PF17383.2 CDS33720.2 - 0.0092 16.3 1.1 0.0092 16.3 1.1 12.5 11 3 5 16 16 16 2 Uncharacterized KorC regulated protein A 7tm_1 PF00001.21 CDS33721.2 - 7.4e-13 48.4 3.9 9.5e-13 48.1 3.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS33721.2 - 2.3e-07 30.4 8.4 2.3e-07 30.4 8.4 1.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw Vpu PF00558.19 CDS33721.2 - 0.0023 17.7 0.2 0.012 15.4 0.1 2.2 2 0 0 2 2 2 1 Vpu protein 7TM_GPCR_Srx PF10328.9 CDS33721.2 - 0.0026 17.4 11.2 0.0026 17.4 11.2 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Orf78 PF06024.12 CDS33721.2 - 0.07 13.4 7.1 16 5.9 0.4 3.3 2 1 1 3 3 3 0 Orf78 (ac78) TMEM154 PF15102.6 CDS33721.2 - 0.13 12.2 3.5 0.15 11.9 0.5 2.2 1 1 1 2 2 2 0 TMEM154 protein family 7tm_3 PF00003.22 CDS33721.2 - 0.41 10.3 8.1 5.8 6.6 6.2 2.4 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4817 PF16087.5 CDS33722.1 - 0.0071 16.1 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) SpoIIID PF12116.8 CDS33722.1 - 0.052 13.6 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D Ion_trans_2 PF07885.16 CDS33723.1 - 4e-36 122.8 15.6 1.1e-19 70.1 0.2 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CDS33723.1 - 7.8e-05 22.0 7.8 0.0036 16.6 0.1 2.2 2 0 0 2 2 2 2 Ion transport protein zf-C2H2_4 PF13894.6 CDS33724.1 - 6.7e-22 76.3 183.1 0.0035 18.1 4.1 20.7 21 0 0 21 21 21 16 C2H2-type zinc finger zf-met PF12874.7 CDS33724.1 - 1.5e-15 57.0 88.7 0.0085 16.5 0.8 15.1 14 0 0 14 14 14 10 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDS33724.1 - 1.1e-11 44.4 187.4 0.0022 18.4 5.1 19.8 21 0 0 21 21 21 12 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS33724.1 - 3.6e-09 36.6 118.1 5e-06 26.7 0.9 17.4 19 0 0 19 19 19 7 Zinc-finger double domain C1_4 PF07975.12 CDS33724.1 - 0.0097 16.1 0.5 0.0097 16.1 0.5 11.8 10 3 2 12 12 12 2 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CDS33724.1 - 0.016 15.5 74.8 0.13 12.6 0.1 14.1 14 0 0 14 14 14 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDS33724.1 - 0.079 13.3 79.1 1.4 9.3 0.1 14.9 10 4 5 16 16 16 0 C2H2 type zinc-finger (2 copies) Collagen PF01391.18 CDS33725.1 - 0.0015 18.3 2.8 0.0025 17.6 2.8 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Transposase_1 PF01359.18 CDS33726.1 - 2.6e-17 62.4 0.1 6.7e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Transposase (partial DDE domain) Copine PF07002.16 CDS33727.1 - 4.2e-56 189.8 0.0 6.1e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CDS33727.1 - 6.2e-07 29.6 0.0 2.8e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 C2 domain vWA-TerF-like PF10138.9 CDS33727.1 - 0.00011 22.4 0.0 0.00023 21.3 0.0 1.5 2 0 0 2 2 2 1 vWA found in TerF C terminus tRNA_int_endo PF01974.17 CDS33728.1 - 6.3e-15 55.0 0.0 1.7e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MBOAT PF03062.19 CDS33728.1 - 1e-12 48.1 17.4 1e-12 48.1 17.4 2.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family TSP_1 PF00090.19 CDS33729.1 - 8.7e-12 45.1 10.6 8.7e-12 45.1 10.6 2.6 3 0 0 3 3 3 1 Thrombospondin type 1 domain EGF_2 PF07974.13 CDS33729.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 3.8 3 3 0 3 3 3 1 EGF-like domain EGF PF00008.27 CDS33729.1 - 0.0019 18.4 17.5 0.034 14.4 6.0 4.0 2 2 0 2 2 2 2 EGF-like domain Cyt_c_ox_IV PF12270.8 CDS33729.1 - 0.047 13.8 0.1 0.079 13.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV cEGF PF12662.7 CDS33729.1 - 0.12 12.3 13.5 0.23 11.4 0.6 3.8 4 0 0 4 4 4 0 Complement Clr-like EGF-like hEGF PF12661.7 CDS33729.1 - 0.46 11.2 14.2 1.3 9.8 0.4 4.5 4 1 0 4 4 4 0 Human growth factor-like EGF Lipocalin PF00061.23 CDS33730.1 - 7.8e-07 29.4 0.3 1e-06 29.0 0.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CDS33730.1 - 6.3e-05 22.9 0.2 7.8e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Band_7 PF01145.25 CDS33732.1 - 1.7e-20 73.7 0.0 1.7e-20 73.7 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CDS33732.1 - 0.00017 21.8 11.8 0.00038 20.7 3.7 3.1 1 1 1 3 3 3 2 Flotillin YjbH PF06082.11 CDS33732.1 - 0.13 11.1 4.1 0.17 10.6 4.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4178 PF13785.6 CDS33732.1 - 0.23 11.6 0.5 0.5 10.5 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4178) Caudo_TAP PF02413.17 CDS33732.1 - 6.1 7.0 8.5 31 4.7 6.5 2.4 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK SEP PF08059.13 CDS33733.1 - 1.2e-23 83.5 0.0 2.7e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDS33733.1 - 4.7e-11 42.7 0.1 9.3e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CDS33733.1 - 3.6e-07 29.9 1.1 6.4e-07 29.1 1.1 1.4 1 0 0 1 1 1 1 UBA-like domain Mis14 PF08641.12 CDS33733.1 - 0.053 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Kinetochore protein Mis14 like CUE PF02845.16 CDS33733.1 - 0.11 12.3 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 CUE domain adh_short PF00106.25 CDS33734.1 - 2.4e-31 108.7 0.0 4.4e-23 81.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33734.1 - 1.9e-24 86.5 0.0 6.9e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS33734.1 - 4.8e-07 29.9 0.0 7.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDS33734.1 - 0.00015 21.3 0.0 0.00084 18.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PSD5 PF07637.11 CDS33734.1 - 0.026 14.9 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) FHA PF00498.26 CDS33735.1 - 4.9e-17 62.0 0.0 1.7e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CDS33735.1 - 1.6e-07 31.6 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Clat_adaptor_s PF01217.20 CDS33736.1 - 1.6e-25 89.7 0.1 2e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FDX-ACB PF03147.14 CDS33736.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain RCC1 PF00415.18 CDS33737.2 - 3.9e-39 133.0 8.7 2.3e-06 28.1 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat DnaJ PF00226.31 CDS33737.2 - 6.2e-17 61.5 0.1 1.2e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain RCC1_2 PF13540.6 CDS33737.2 - 5.6e-15 54.7 27.5 9.1e-08 31.7 0.6 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.27 CDS33738.2 - 3e-64 216.8 0.0 8.9e-64 215.3 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.24 CDS33738.2 - 2.4e-46 155.7 0.1 2.8e-22 78.6 0.0 2.4 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.20 CDS33738.2 - 0.0018 18.1 0.1 0.0043 16.9 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS33738.2 - 0.028 14.5 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDS33738.2 - 0.035 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ank_2 PF12796.7 CDS33739.1 - 4.1e-35 120.2 1.1 1.2e-15 57.8 0.0 5.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS33739.1 - 2.7e-27 94.8 8.9 1.3e-07 32.1 0.1 6.8 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS33739.1 - 2.1e-23 82.1 9.7 3.3e-06 27.3 0.7 6.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CDS33739.1 - 4.6e-19 67.9 14.3 0.035 14.6 0.1 8.0 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 CDS33739.1 - 2.2e-14 52.1 9.4 0.011 16.1 0.0 8.1 9 0 0 9 9 9 3 Ankyrin repeat NACHT PF05729.12 CDS33739.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDS33739.1 - 0.0021 18.5 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CDS33739.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDS33739.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sugar_tr PF00083.24 CDS33740.1 - 5.1e-24 84.9 24.2 1.3e-23 83.6 24.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDS33740.1 - 1.4e-14 53.8 21.4 1.4e-14 53.8 21.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4408 PF14364.6 CDS33740.1 - 0.23 11.2 3.2 0.62 9.8 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) DUF5027 PF16430.5 CDS33742.1 - 0.097 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) DnaJ PF00226.31 CDS33743.1 - 1.7e-21 76.1 0.5 4.2e-21 74.8 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 CDS33743.1 - 1.5e-10 41.0 0.2 0.00017 21.7 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDS33743.1 - 1e-05 25.7 0.2 0.26 11.6 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4611 PF15387.6 CDS33743.1 - 0.52 10.6 11.5 0.73 10.1 1.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Tubulin PF00091.25 CDS33744.1 - 9.3e-66 221.8 0.0 1.4e-65 221.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS33744.1 - 1.3e-45 154.6 0.1 4.7e-45 152.8 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS33744.1 - 0.00055 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDS33744.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin like DUF480 PF04337.12 CDS33744.1 - 0.02 15.0 0.3 0.089 12.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF480 ATG_C PF09333.11 CDS33745.1 - 2e-17 63.3 0.0 5.8e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 CDS33745.1 - 0.078 12.7 0.2 0.21 11.3 0.2 1.7 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif LRR_8 PF13855.6 CDS33746.1 - 1.2e-27 95.4 31.9 1.4e-07 31.2 9.5 9.1 6 3 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 CDS33746.1 - 2.3e-10 40.6 43.0 0.016 15.6 7.6 9.5 6 3 4 11 11 11 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CDS33746.1 - 8.3e-09 35.5 5.0 0.12 12.3 0.2 5.3 4 1 1 5 5 5 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CDS33746.1 - 0.00011 22.2 31.2 0.038 14.5 0.0 10.6 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_9 PF14580.6 CDS33746.1 - 0.015 14.8 7.5 2.7 7.5 1.2 4.4 2 1 2 4 4 4 0 Leucine-rich repeat MAP17 PF15807.5 CDS33746.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3139 PF11337.8 CDS33746.1 - 0.092 13.4 0.7 0.25 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) FNIP PF05725.12 CDS33746.1 - 0.57 10.4 0.0 0.57 10.4 0.0 4.1 5 1 0 5 5 5 0 FNIP Repeat c-SKI_SMAD_bind PF08782.10 CDS33748.1 - 0.0065 16.7 1.4 0.011 16.0 1.4 1.4 1 0 0 1 1 1 1 c-SKI Smad4 binding domain PAN_2 PF08276.11 CDS33748.1 - 0.046 13.8 3.0 0.073 13.2 3.0 1.3 1 0 0 1 1 1 0 PAN-like domain GrpB PF04229.14 CDS33748.1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 GrpB protein Ank_5 PF13857.6 CDS33749.1 - 9.1e-12 45.0 2.2 2e-05 24.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33749.1 - 3.8e-11 43.4 0.8 2e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS33749.1 - 6.7e-11 42.5 1.2 1.5e-07 31.8 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33749.1 - 3.6e-08 33.0 0.9 0.094 13.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CDS33749.1 - 0.009 16.4 3.1 1.8 9.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat DUF3421 PF11901.8 CDS33751.1 - 3.6e-07 30.2 0.0 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) RhoGAP PF00620.27 CDS33752.1 - 6.3e-39 133.2 0.0 2.5e-38 131.3 0.0 2.1 1 0 0 1 1 1 1 RhoGAP domain Gp_dh_C PF02800.20 CDS33753.1 - 3.2e-66 221.8 0.0 4.8e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDS33753.1 - 1.8e-34 118.1 0.0 4.3e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF4367 PF14285.6 CDS33753.1 - 0.0021 18.5 0.2 0.022 15.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4367) Ran_BP1 PF00638.18 CDS33754.1 - 3.6e-06 27.2 0.0 6.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NPDC1 PF06809.11 CDS33755.1 - 0.00065 18.8 0.6 0.0028 16.8 0.6 1.9 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Adeno_E3_CR2 PF02439.15 CDS33755.1 - 0.0021 17.8 2.3 0.0045 16.7 2.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 CDS33755.1 - 0.0027 18.6 0.0 0.0043 17.9 0.0 1.5 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Prominin PF05478.11 CDS33755.1 - 0.03 12.3 0.1 0.033 12.2 0.1 1.1 1 0 0 1 1 1 0 Prominin GRA6 PF05084.13 CDS33755.1 - 0.034 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TMEM154 PF15102.6 CDS33755.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PTP_tm PF18861.1 CDS33755.1 - 0.063 13.3 1.8 0.063 13.3 1.8 1.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Phage_holin_2_1 PF04971.12 CDS33755.1 - 0.087 12.8 0.4 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF4834 PF16118.5 CDS33755.1 - 0.087 13.8 0.0 0.18 12.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 CDS33755.1 - 0.092 13.0 0.2 0.19 11.9 0.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAM176 PF14851.6 CDS33755.1 - 0.099 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF5385 PF17359.2 CDS33755.1 - 0.13 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF4514 PF14986.6 CDS33755.1 - 0.38 10.7 0.2 0.38 10.7 0.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4514) Syndecan PF01034.20 CDS33755.1 - 4.8 7.2 8.6 14 5.7 8.6 2.0 1 1 0 1 1 1 0 Syndecan domain Ras PF00071.22 CDS33756.1 - 3.1e-56 189.4 0.0 3.6e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS33756.1 - 2.2e-23 82.8 0.0 3.3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS33756.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDS33756.1 - 0.0014 18.2 0.1 0.0028 17.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDS33756.1 - 0.0035 16.7 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDS33756.1 - 0.0092 15.4 0.0 0.021 14.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ldh_1_N PF00056.23 CDS33756.1 - 0.081 13.0 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain UPF0489 PF12640.7 CDS33757.1 - 7.8e-10 39.3 0.1 1.8e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 UPF0489 domain tRNA_bind PF01588.20 CDS33758.1 - 5e-29 100.3 0.0 8e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain MPS-4 PF17523.2 CDS33758.1 - 0.33 11.1 2.5 0.59 10.3 2.5 1.4 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Pkinase PF00069.25 CDS33759.1 - 2e-77 260.1 6.3 1.8e-42 145.5 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain WD40 PF00400.32 CDS33759.1 - 1e-19 70.5 16.5 0.00031 21.5 0.1 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 CDS33759.1 - 4.1e-15 55.8 1.2 9.5e-08 31.6 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 CDS33759.1 - 3e-05 24.2 0.0 0.54 10.6 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain APH PF01636.23 CDS33759.1 - 0.0005 20.1 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDS33759.1 - 0.15 11.4 0.9 7 5.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ECSIT PF06239.11 CDS33759.1 - 0.16 11.1 0.0 0.44 9.6 0.0 1.7 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Pesticin PF16754.5 CDS33759.1 - 0.22 11.5 0.3 0.56 10.2 0.2 1.6 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term ABC_tran PF00005.27 CDS33760.1 - 1.3e-47 161.8 0.0 4.3e-23 82.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CDS33760.1 - 1.8e-24 85.6 4.4 6.6e-24 83.8 0.4 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CDS33760.1 - 3.8e-13 49.9 13.5 0.00086 19.2 0.1 5.3 3 2 2 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDS33760.1 - 7.7e-11 41.8 0.3 0.00014 21.3 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDS33760.1 - 1.4e-07 31.9 0.1 0.015 15.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDS33760.1 - 2.7e-07 31.1 0.2 0.0017 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 CDS33760.1 - 2.7e-06 27.4 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 CDS33760.1 - 3.6e-06 26.9 1.1 0.086 12.5 0.0 3.2 3 1 1 4 4 3 2 AAA ATPase domain AAA_29 PF13555.6 CDS33760.1 - 4.8e-06 26.2 0.1 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 CDS33760.1 - 1.1e-05 25.4 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 CDS33760.1 - 2e-05 25.0 0.0 0.046 14.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CDS33760.1 - 3e-05 24.0 0.8 0.069 13.0 0.0 3.0 2 1 1 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 CDS33760.1 - 6.7e-05 23.5 11.7 0.0065 17.0 0.0 3.6 3 1 1 4 4 3 2 AAA domain AAA_28 PF13521.6 CDS33760.1 - 7.4e-05 23.1 0.0 0.45 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CDS33760.1 - 0.00021 21.1 0.0 0.51 10.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CDS33760.1 - 0.00037 20.7 0.0 0.63 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF2813 PF11398.8 CDS33760.1 - 0.00047 19.5 0.1 0.99 8.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) Roc PF08477.13 CDS33760.1 - 0.001 19.3 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CDS33760.1 - 0.0012 18.6 0.0 2.8 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CDS33760.1 - 0.0018 18.8 0.0 1.9 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CDS33760.1 - 0.0027 16.9 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 CDS33760.1 - 0.0062 16.5 0.1 3.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 CDS33760.1 - 0.008 16.1 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CDS33760.1 - 0.0085 15.4 0.0 0.63 9.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.9 CDS33760.1 - 0.01 15.6 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 CDS33760.1 - 0.012 15.7 0.0 11 6.0 0.0 3.5 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 CDS33760.1 - 0.013 15.1 0.2 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CDS33760.1 - 0.016 15.6 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 CDS33760.1 - 0.028 14.5 0.8 0.75 9.8 0.0 3.3 3 1 0 3 3 3 0 Dynamin family AAA_13 PF13166.6 CDS33760.1 - 0.033 12.9 2.4 3.3 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 CDS33760.1 - 0.033 13.0 0.4 11 4.6 0.1 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 CDS33760.1 - 0.035 14.1 0.2 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 CDS33760.1 - 0.06 12.3 0.0 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 CDS33760.1 - 0.065 12.8 0.2 2.9 7.4 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 CDS33760.1 - 0.065 13.3 8.2 0.08 13.0 0.0 3.6 4 0 0 4 4 3 0 Helicase HerA, central domain Arf PF00025.21 CDS33760.1 - 0.084 12.3 0.1 5.3 6.5 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family Septin PF00735.18 CDS33760.1 - 0.085 12.1 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 CDS33760.1 - 0.13 11.7 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CDS33760.1 - 0.13 12.1 0.1 8.8 6.2 0.0 2.6 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 CDS33760.1 - 0.14 12.1 0.0 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CLP1_P PF16575.5 CDS33760.1 - 0.14 11.9 0.2 12 5.7 0.1 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3584 PF12128.8 CDS33760.1 - 7.4 3.9 8.8 1.1 6.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA PF00004.29 CDS33761.1 - 7.6e-43 146.1 0.0 1.3e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDS33761.1 - 1e-10 41.4 0.5 2e-10 40.5 0.5 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDS33761.1 - 1.1e-09 37.9 0.1 2.1e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDS33761.1 - 5.6e-07 29.8 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDS33761.1 - 6e-06 26.6 0.1 0.0039 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CDS33761.1 - 2.7e-05 24.0 0.0 5.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDS33761.1 - 2.8e-05 23.4 0.0 5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CDS33761.1 - 3.2e-05 24.4 0.1 0.0019 18.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDS33761.1 - 7.8e-05 22.7 0.2 0.00061 19.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDS33761.1 - 0.00075 20.0 0.0 0.0039 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDS33761.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 CDS33761.1 - 0.0017 18.2 0.2 0.92 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CDS33761.1 - 0.0033 17.6 0.0 0.0083 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDS33761.1 - 0.0037 17.3 0.1 0.01 15.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CDS33761.1 - 0.0046 17.2 0.1 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CDS33761.1 - 0.0048 16.3 0.8 0.32 10.3 0.0 3.0 2 1 1 3 3 3 1 KaiC Prot_ATP_OB_N PF17758.1 CDS33761.1 - 0.0084 15.7 0.2 0.025 14.2 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 CDS33761.1 - 0.011 15.4 0.4 0.45 10.1 0.2 2.6 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDS33761.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CDS33761.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CDS33761.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CDS33761.1 - 0.02 14.4 0.1 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 CDS33761.1 - 0.029 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDS33761.1 - 0.033 13.9 0.9 0.075 12.7 0.2 2.1 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CDS33761.1 - 0.047 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CDS33761.1 - 0.048 13.4 0.2 0.11 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDS33761.1 - 0.05 13.1 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 CDS33761.1 - 0.057 13.6 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 CDS33761.1 - 0.069 12.3 0.1 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 CDS33761.1 - 0.096 13.2 0.1 0.43 11.1 0.0 2.2 3 0 0 3 3 2 0 ABC transporter NACHT PF05729.12 CDS33761.1 - 0.11 12.4 0.1 0.57 10.1 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 CDS33761.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 CDS33761.1 - 0.11 12.3 1.0 1.2 9.0 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CDS33761.1 - 0.14 11.9 0.1 0.52 10.0 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain Sec7 PF01369.20 CDS33762.1 - 8.4e-43 146.2 0.1 1.4e-42 145.5 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 CDS33762.1 - 2e-12 47.3 0.1 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 PH domain CAP_GLY PF01302.25 CDS33763.1 - 2.9e-18 65.6 0.2 5.3e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 CDS33763.1 - 3.2e-10 39.8 2.7 1.7e-09 37.4 1.4 2.4 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CDS33763.1 - 5.6e-08 33.0 19.7 0.012 16.0 7.4 5.4 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS33763.1 - 1.5e-05 24.7 13.8 0.00022 20.9 7.9 4.6 3 2 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 CDS33763.1 - 2.6 8.3 11.9 72 3.8 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich repeat Asparaginase_2 PF01112.18 CDS33764.1 - 6.3e-75 252.0 0.1 8.2e-75 251.7 0.1 1.0 1 0 0 1 1 1 1 Asparaginase PUB PF09409.10 CDS33765.2 - 0.002 18.1 1.1 2.2 8.3 0.0 3.2 3 0 0 3 3 3 2 PUB domain GHMP_kinases_C PF08544.13 CDS33765.2 - 0.0027 18.0 0.4 0.061 13.7 0.2 2.9 3 0 0 3 3 3 1 GHMP kinases C terminal HAUS-augmin3 PF14932.6 CDS33765.2 - 0.0097 15.5 11.6 0.23 11.0 6.2 2.9 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 3 Trimer_CC PF08954.11 CDS33765.2 - 0.019 14.5 1.0 0.1 12.2 0.0 2.6 2 0 0 2 2 2 0 Trimerisation motif TPR_MLP1_2 PF07926.12 CDS33765.2 - 0.03 14.4 1.7 0.03 14.4 1.7 3.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CDS33765.2 - 0.068 13.2 0.6 0.068 13.2 0.6 4.1 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SIKE PF05769.11 CDS33765.2 - 0.077 12.9 11.9 7.6 6.4 5.5 3.7 1 1 3 4 4 4 0 SIKE family HEPN PF05168.14 CDS33765.2 - 0.08 13.1 0.6 2.2 8.5 0.0 3.2 4 0 0 4 4 4 0 HEPN domain LRRFIP PF09738.9 CDS33765.2 - 0.29 10.6 10.1 0.065 12.7 5.6 2.0 1 1 1 2 2 2 0 LRRFIP family GIT_CC PF16559.5 CDS33765.2 - 1.9 8.4 7.4 2.1 8.3 0.1 3.9 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 CDS33765.2 - 2.9 8.4 11.5 13 6.3 0.2 4.8 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Noelin-1 PF12308.8 CDS33765.2 - 2.9 7.9 8.5 17 5.5 0.3 3.7 4 0 0 4 4 4 0 Neurogenesis glycoprotein DDHD PF02862.17 CDS33766.2 - 1.3e-27 97.5 0.3 2.2e-27 96.7 0.3 1.3 1 0 0 1 1 1 1 DDHD domain WWE PF02825.20 CDS33766.2 - 0.0017 18.9 0.1 0.0052 17.3 0.1 1.9 1 0 0 1 1 1 1 WWE domain Ribosomal_L19e PF01280.20 CDS33767.1 - 5.6e-58 195.1 10.0 5.6e-58 195.1 10.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e Pkinase PF00069.25 CDS33768.1 - 9.6e-72 241.5 0.0 1.2e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33768.1 - 4.8e-28 98.1 0.0 7.4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CDS33768.1 - 2.2e-10 40.7 0.6 6.6e-09 36.0 0.3 3.0 2 1 0 2 2 2 1 FHA domain Kinase-like PF14531.6 CDS33768.1 - 3.2e-05 23.4 0.0 5.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 CDS33768.1 - 0.0082 15.2 0.1 0.022 13.7 0.1 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CDS33768.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CDS33768.1 - 0.054 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2218 PF09981.9 CDS33769.1 - 0.035 14.5 0.0 1.6 9.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) PDZ PF00595.24 CDS33770.1 - 1.1e-08 35.3 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS33770.1 - 9.8e-05 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDS33770.1 - 0.03 14.6 0.0 0.09 13.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain F_actin_cap_B PF01115.17 CDS33771.1 - 3.6e-93 311.6 0.0 4.3e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit TILa PF12714.7 CDS33772.1 - 0.0047 16.9 1.1 0.011 15.6 1.1 1.6 1 0 0 1 1 1 1 TILa domain RPW8 PF05659.11 CDS33772.1 - 0.098 12.3 0.3 0.098 12.3 0.3 3.0 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ribosomal_L19e PF01280.20 CDS33773.1 - 3.5e-57 192.5 7.8 3.5e-57 192.5 7.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e DUF4551 PF15087.6 CDS33773.1 - 8 5.2 10.3 12 4.6 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BRCA-2_OB1 PF09103.10 CDS33775.1 - 3.3e-31 107.8 0.0 1.3e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 VWA_3 PF13768.6 CDS33775.1 - 9.3e-18 64.6 0.0 2.6e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 CDS33775.1 - 4e-16 59.2 0.0 1e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain BRCA2 PF00634.18 CDS33775.1 - 4.2e-09 35.9 5.8 0.015 15.0 0.0 5.9 5 1 0 5 5 5 3 BRCA2 repeat BRCA-2_helical PF09169.10 CDS33775.1 - 7.1e-08 32.3 0.5 4.8e-07 29.6 0.1 2.5 2 1 0 2 2 2 1 BRCA2, helical VIT_2 PF13757.6 CDS33775.1 - 2e-06 27.6 0.0 6.9e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 CDS33775.1 - 1.8e-05 25.1 0.0 0.00069 19.9 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain DM PF00751.18 CDS33776.1 - 6.9e-29 99.5 30.5 2.5e-14 52.9 12.3 2.4 2 0 0 2 2 2 2 DM DNA binding domain AMP-binding PF00501.28 CDS33777.2 - 4.6e-81 272.6 0.0 6e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CDS33777.2 - 8.6e-18 64.0 3.2 2.6e-17 62.5 3.2 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CDS33777.2 - 5.2e-17 62.6 0.3 1e-16 61.6 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DZF PF07528.14 CDS33778.1 - 4.1e-44 151.1 0.4 8.9e-42 143.4 0.4 2.2 1 1 0 1 1 1 1 DZF domain RhoGEF PF00621.20 CDS33779.2 - 2.4e-07 31.2 3.6 1.3e-06 28.8 0.0 2.6 2 0 0 2 2 2 1 RhoGEF domain PH_16 PF17838.1 CDS33779.2 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 PH domain YqhG PF11079.8 CDS33779.2 - 0.11 11.4 3.0 0.22 10.4 3.0 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Jnk-SapK_ap_N PF09744.9 CDS33779.2 - 0.78 9.9 22.6 4.1 7.6 9.8 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ALC PF17527.2 CDS33779.2 - 3.6 7.2 6.6 0.56 9.8 2.1 1.9 2 0 0 2 2 2 0 Phage ALC protein 7tm_1 PF00001.21 CDS33780.1 - 1.4e-62 211.4 2.1 2.8e-62 210.4 2.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS33780.1 - 2.4e-17 63.2 8.0 1.4e-13 50.9 5.9 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CDS33780.1 - 5.3e-10 39.4 12.4 5.3e-10 39.4 12.4 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CDS33780.1 - 0.0003 20.6 2.9 0.0003 20.6 2.9 2.1 2 0 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srbc PF10316.9 CDS33780.1 - 0.0051 16.3 7.6 0.0051 16.3 7.6 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Serpentine_r_xa PF03383.15 CDS33780.1 - 0.32 11.0 5.3 0.26 11.2 2.1 2.3 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Myelin_PLP PF01275.19 CDS33781.1 - 5.2e-07 29.8 0.0 5.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) HopW1-1 PF15457.6 CDS33781.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Pkinase PF00069.25 CDS33782.1 - 2.4e-47 161.5 0.0 6.4e-47 160.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33782.1 - 1.5e-20 73.6 0.0 4.2e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Sel1 PF08238.12 CDS33783.1 - 8.5e-17 61.2 6.0 0.0012 19.4 1.1 6.6 6 0 0 6 6 6 4 Sel1 repeat TPR_1 PF00515.28 CDS33783.1 - 2.5e-07 30.2 1.1 0.00054 19.7 0.3 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS33783.1 - 3.6e-06 26.7 0.8 0.00037 20.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS33783.1 - 3e-05 23.9 5.5 0.018 15.2 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS33783.1 - 0.00043 20.4 0.7 0.0041 17.3 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDS33783.1 - 0.00058 19.7 0.0 0.019 15.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS33783.1 - 0.00093 18.8 0.3 0.097 12.4 0.1 3.5 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 CDS33783.1 - 0.0056 16.9 0.1 0.12 12.6 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDS33783.1 - 0.018 15.7 0.3 0.2 12.4 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS33783.1 - 0.02 15.5 0.0 5.9 7.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDS33783.1 - 0.035 14.9 0.0 1.1 10.3 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat MIT PF04212.18 CDS33783.1 - 1.5 9.0 3.3 26 5.0 0.1 3.8 3 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain VEFS-Box PF09733.9 CDS33784.1 - 2.4e-30 105.1 0.3 5e-30 104.1 0.3 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Glyco_hydro_31 PF01055.26 CDS33785.1 - 4.4e-136 454.6 4.7 5.8e-136 454.2 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDS33785.1 - 3.5e-25 88.1 1.4 9.3e-25 86.7 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Gal-bind_lectin PF00337.22 CDS33785.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 1 0 1 1 1 0 Galactoside-binding lectin ASC PF00858.24 CDS33786.1 - 7.1e-12 45.0 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel BST2 PF16716.5 CDS33786.1 - 0.026 15.1 0.1 0.026 15.1 0.1 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DLIC PF05783.11 CDS33786.1 - 0.038 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Pectate_lyase PF03211.13 CDS33786.1 - 0.087 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Pectate lyase Filamin PF00630.19 CDS33789.1 - 0 1030.7 29.4 1.8e-18 67.3 0.0 22.2 22 0 0 22 22 22 22 Filamin/ABP280 repeat CH PF00307.31 CDS33789.1 - 1.7e-39 134.4 0.5 2.1e-21 76.1 0.2 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Y_Y_Y PF07495.13 CDS33789.1 - 5.5e-16 58.3 2.6 0.02 14.9 0.0 9.4 11 0 0 11 11 11 4 Y_Y_Y domain Big_3_5 PF16640.5 CDS33789.1 - 7.2e-07 29.3 24.0 2.6 8.3 0.0 12.3 14 0 0 14 14 14 1 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 CDS33789.1 - 1.8e-06 28.2 10.7 0.88 9.9 0.0 8.9 12 0 0 12 12 12 2 Invasin, domain 3 CAMSAP_CH PF11971.8 CDS33789.1 - 0.00026 20.8 0.0 0.73 9.7 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain TIG PF01833.24 CDS33789.1 - 0.008 16.2 4.6 46 4.2 0.0 7.0 7 0 0 7 7 7 0 IPT/TIG domain CH_2 PF06294.11 CDS33789.1 - 0.012 15.8 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 CH-like domain in sperm protein SH2 PF00017.24 CDS33789.1 - 0.18 11.9 0.0 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 SH2 domain DUF1541 PF07563.11 CDS33789.1 - 2.3 8.2 4.5 40 4.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1541) RINGv PF12906.7 CDS33790.1 - 9.8e-14 51.2 10.6 2.1e-13 50.1 10.6 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 CDS33790.1 - 0.082 13.1 4.6 0.17 12.1 4.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CDS33790.1 - 0.36 11.2 9.0 0.15 12.4 6.3 1.9 2 0 0 2 2 2 0 Ring finger domain DSPc PF00782.20 CDS33791.1 - 7.7e-07 29.0 0.0 1.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS33791.1 - 0.00017 21.3 0.0 0.00021 20.9 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDS33791.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family PK PF00224.21 CDS33796.1 - 5.5e-83 278.7 0.0 9.3e-83 278.0 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDS33796.1 - 8.5e-24 84.0 0.3 2.2e-23 82.7 0.3 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDS33796.1 - 0.021 14.0 0.0 0.062 12.4 0.0 1.8 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family GST_C_2 PF13410.6 CDS33797.1 - 3.4e-09 36.6 0.0 8.7e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS33797.1 - 5.7e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDS33797.1 - 5.4e-05 23.3 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-H2C2_2 PF13465.6 CDS33798.1 - 3.1e-09 36.9 31.3 4e-06 27.0 3.1 5.5 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CDS33798.1 - 7.2e-09 35.6 31.6 0.0012 19.2 3.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS33798.1 - 8.3e-09 35.6 30.0 0.00047 20.8 2.7 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS33798.1 - 5.2e-05 23.4 21.3 0.0099 16.1 3.6 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS33798.1 - 0.008 16.5 1.7 0.008 16.5 1.7 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-FPG_IleRS PF06827.14 CDS33798.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-C2H2_6 PF13912.6 CDS33798.1 - 0.6 10.2 27.6 0.08 13.0 2.0 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Ta0938 PF11494.8 CDS33798.1 - 4.9 7.5 7.2 1.7 9.0 0.4 2.9 1 1 2 3 3 3 0 Ta0938 DUF2256 PF10013.9 CDS33798.1 - 5.5 7.2 13.5 1.1 9.4 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 CDS33798.1 - 5.7 6.9 6.1 8.6 6.3 0.0 3.1 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Mob1_phocein PF03637.17 CDS33799.1 - 3e-35 121.7 2.0 3.7e-35 121.4 2.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family F-box-like PF12937.7 CDS33799.1 - 0.059 13.3 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 F-box-like Rep_fac-A_C PF08646.10 CDS33800.1 - 9.3e-51 171.4 4.3 2.7e-49 166.7 1.0 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDS33800.1 - 3.7e-29 100.5 0.5 1.6e-28 98.5 0.1 2.1 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 CDS33800.1 - 2.5e-23 82.0 0.1 6.4e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CDS33800.1 - 3.5e-09 36.5 4.9 6.1e-09 35.7 0.0 3.6 4 1 1 5 5 5 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CDS33800.1 - 0.025 14.3 0.6 3 7.5 0.1 2.8 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 TLD PF07534.16 CDS33801.1 - 2.7e-17 63.3 0.0 1.7e-16 60.7 0.0 2.1 1 1 1 2 2 2 1 TLD RabGAP-TBC PF00566.18 CDS33801.1 - 0.0024 17.5 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain UPF0220 PF05255.11 CDS33802.1 - 1.7e-25 89.5 2.0 2.2e-25 89.1 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) EI24 PF07264.11 CDS33802.1 - 1.9 8.7 10.0 0.89 9.8 4.4 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) IKI3 PF04762.12 CDS33803.1 - 1.3e-143 480.2 0.0 2.5e-143 479.2 0.0 1.4 1 1 0 1 1 1 1 IKI3 family PhaP_Bmeg PF09602.10 CDS33803.1 - 0.0057 16.6 0.2 0.043 13.7 0.1 2.2 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TPR_16 PF13432.6 CDS33803.1 - 0.29 11.8 4.7 5 7.9 2.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PA PF02225.22 CDS33804.1 - 3.8e-08 33.2 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 PA domain FYVE PF01363.21 CDS33805.1 - 3.6e-05 23.8 12.8 3.6e-05 23.8 12.8 2.6 2 1 0 2 2 2 1 FYVE zinc finger DUF4193 PF13834.6 CDS33805.1 - 0.00019 21.9 0.4 0.00067 20.1 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) zf-4CXXC_R1 PF10497.9 CDS33805.1 - 0.17 12.2 17.6 0.22 11.8 8.3 2.5 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ODR4-like PF14778.6 CDS33806.1 - 3.4e-31 108.5 0.0 1.1e-30 106.8 0.0 1.7 2 0 0 2 2 2 1 Olfactory receptor 4-like EndIII_4Fe-2S PF10576.9 CDS33806.1 - 0.36 11.2 3.0 0.69 10.3 3.0 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III SAYSvFN PF10260.9 CDS33807.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) ANAPC4_WD40 PF12894.7 CDS33808.1 - 0.056 13.8 0.0 1.2 9.4 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS33808.1 - 0.1 13.5 7.2 1.4e+02 3.6 0.0 6.7 7 1 0 7 7 7 0 WD domain, G-beta repeat rve PF00665.26 CDS33814.2 - 3.3e-18 66.0 0.0 7.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS33814.2 - 1.4e-07 31.5 0.6 3.4e-07 30.3 0.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDS33814.2 - 2.6e-06 27.7 0.1 5.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 CDS33814.2 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDS33814.2 - 0.1 12.8 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger TPR_2 PF07719.17 CDS33816.2 - 1.5e-16 59.1 22.6 0.00014 21.7 0.1 8.8 12 0 0 12 12 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDS33816.2 - 2.6e-13 49.2 17.8 0.00048 19.8 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS33816.2 - 6.1e-12 46.0 0.0 0.00044 20.8 0.0 5.6 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDS33816.2 - 7.9e-10 38.9 13.9 0.045 14.0 1.6 6.6 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS33816.2 - 8.7e-10 38.6 0.1 0.33 11.9 0.0 6.5 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS33816.2 - 1.4e-09 38.0 14.1 0.00037 20.9 0.0 7.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS33816.2 - 1.5e-08 35.0 7.5 0.027 15.0 0.0 5.9 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDS33816.2 - 3e-08 33.2 21.1 0.093 13.0 0.0 8.7 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDS33816.2 - 5.4e-08 32.4 16.8 7.4e-08 32.0 0.2 5.0 5 0 0 5 5 4 1 TPR repeat TPR_7 PF13176.6 CDS33816.2 - 3.1e-07 29.9 21.2 3.3 7.9 0.0 9.7 12 0 0 12 12 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS33816.2 - 7e-05 23.0 8.0 0.068 13.4 0.9 3.8 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_2 PF10367.9 CDS33816.2 - 0.00022 21.6 2.7 2.4 8.6 0.1 3.6 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 2 LUC7 PF03194.15 CDS33816.2 - 0.00079 19.2 1.4 1.1 8.9 0.1 2.5 2 0 0 2 2 2 2 LUC7 N_terminus DUF2180 PF09947.9 CDS33816.2 - 0.001 19.0 0.5 2.7 8.0 0.1 2.9 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2180) RPN7 PF10602.9 CDS33816.2 - 0.0011 18.7 5.7 0.84 9.3 0.2 4.6 4 0 0 4 4 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.6 CDS33816.2 - 0.0023 17.7 14.6 9.6 6.2 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DsrD PF08679.11 CDS33816.2 - 0.0047 17.2 2.1 3.5 7.9 0.2 2.7 2 0 0 2 2 2 2 Dissimilatory sulfite reductase D (DsrD) TPR_MalT PF17874.1 CDS33816.2 - 0.013 14.9 3.6 0.088 12.2 0.3 3.0 3 0 0 3 3 3 0 MalT-like TPR region Coatomer_E PF04733.14 CDS33816.2 - 0.025 14.0 3.4 0.43 10.0 0.3 3.0 2 1 1 3 3 3 0 Coatomer epsilon subunit MIT PF04212.18 CDS33816.2 - 0.042 13.9 4.6 19 5.4 0.0 5.0 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 CDS33816.2 - 0.046 13.9 7.8 5.5 7.2 0.3 5.7 6 1 0 7 7 6 0 Tetratricopeptide repeat ZapA PF05164.13 CDS33816.2 - 0.055 13.9 7.9 2.1 8.8 0.3 3.1 3 0 0 3 3 2 0 Cell division protein ZapA FAM25 PF15825.5 CDS33816.2 - 0.06 13.7 2.1 28 5.2 0.0 3.7 2 2 2 4 4 4 0 FAM25 family DUF2183 PF09949.9 CDS33816.2 - 0.065 13.6 0.0 5.3 7.4 0.0 3.3 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2183) NARP1 PF12569.8 CDS33816.2 - 0.12 11.3 14.7 0.2 10.5 0.1 4.5 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 RF3_C PF16658.5 CDS33816.2 - 0.13 12.1 0.0 26 4.6 0.0 2.5 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain RPM2 PF08579.11 CDS33816.2 - 0.15 12.5 2.7 24 5.3 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_21 PF09976.9 CDS33816.2 - 0.17 11.5 4.0 0.12 12.0 1.4 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat-like domain DUF148 PF02520.17 CDS33816.2 - 1.2 9.3 6.3 40 4.4 0.1 4.4 5 0 0 5 5 4 0 Domain of unknown function DUF148 Shugoshin_N PF07558.11 CDS33816.2 - 1.5 8.8 7.2 12 5.8 0.8 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TPR_17 PF13431.6 CDS33816.2 - 9.7 6.8 9.2 0.66 10.5 0.1 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CDS33817.2 - 9e-70 230.5 0.2 4.7e-19 68.0 0.1 4.1 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CDS33817.2 - 0.00011 21.7 0.2 0.011 15.3 0.0 2.9 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 CDS33817.2 - 0.00088 19.1 0.1 0.039 13.8 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CDS33817.2 - 0.0011 18.5 0.1 1.1 8.8 0.1 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDS33817.2 - 0.0015 18.5 0.1 4.6 7.3 0.0 3.9 3 1 1 4 4 4 1 RNA binding motif DUF4523 PF15023.6 CDS33817.2 - 0.0059 16.5 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4523) ORC4_C PF14629.6 CDS33819.1 - 9.2e-30 103.6 0.1 1.6e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CDS33819.1 - 6.7e-11 42.9 0.2 1.4e-10 41.9 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDS33819.1 - 2.4e-06 27.8 0.1 5.9e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDS33819.1 - 2e-05 25.0 0.0 6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CDS33819.1 - 0.00065 18.9 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 CDS33819.1 - 0.0081 16.1 3.5 0.011 15.7 0.3 2.7 2 1 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 CDS33819.1 - 0.022 14.7 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDS33819.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDS33819.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CDS33819.1 - 0.034 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CDS33819.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CDS33819.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.6 CDS33819.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 CDS33819.1 - 0.075 11.9 0.0 0.7 8.7 0.0 2.4 3 0 0 3 3 3 0 P-loop Domain of unknown function (DUF2791) T2SSE PF00437.20 CDS33819.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Microtub_bd PF16796.5 CDS33819.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding Bac_DnaA PF00308.18 CDS33819.1 - 0.11 12.3 0.4 0.37 10.6 0.0 2.1 3 0 0 3 3 3 0 Bacterial dnaA protein G-alpha PF00503.20 CDS33819.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit cobW PF02492.19 CDS33819.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CDS33819.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Prenyltrans PF00432.21 CDS33819.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat MBOAT PF03062.19 CDS33820.2 - 1.3e-14 54.3 15.8 2.1e-12 47.1 15.8 2.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LicD PF04991.13 CDS33821.1 - 0.021 15.0 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 LicD family MMR_HSR1 PF01926.23 CDS33822.1 - 4.6e-14 52.5 0.0 9.5e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 CDS33822.1 - 0.00047 20.8 0.1 0.0015 19.2 0.0 1.9 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal FeoB_N PF02421.18 CDS33822.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDS33822.1 - 0.092 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain GTP-bdg_M PF16360.5 CDS33822.1 - 0.4 11.3 13.6 2.3 8.9 13.6 2.1 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Aldose_epim PF01263.20 CDS33823.1 - 9.5e-63 212.3 0.0 1.6e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase PRKCSH PF07915.13 CDS33824.2 - 8.7e-10 39.5 0.3 2e-09 38.3 0.3 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein zf-C2H2_4 PF13894.6 CDS33826.2 - 2.3e-07 31.0 22.0 0.00046 20.8 0.7 5.6 6 0 0 6 6 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS33826.2 - 1.4e-06 28.5 5.9 0.013 15.8 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDS33826.2 - 1.5e-06 28.4 10.9 0.00054 20.3 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CDS33826.2 - 3.3e-05 24.1 1.3 3.3e-05 24.1 1.3 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDS33826.2 - 0.00031 21.0 5.1 0.0024 18.2 1.2 5.1 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS33826.2 - 0.017 15.6 1.6 0.017 15.6 1.6 4.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_9 PF16293.5 CDS33826.2 - 0.093 12.6 10.5 0.15 11.9 0.1 4.0 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 CDS33826.2 - 0.3 11.4 6.7 7.3 7.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon zf-NADH-PPase PF09297.11 CDS33826.2 - 0.38 10.5 4.3 0.69 9.6 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FOXP-CC PF16159.5 CDS33826.2 - 0.61 10.7 4.7 0.52 11.0 0.3 2.6 3 0 0 3 3 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 CDS33826.2 - 1.3 8.8 10.9 1.6 8.5 0.2 3.2 3 0 0 3 3 2 0 C2H2-type zinc-finger domain His_Me_b4a2 PF18275.1 CDS33826.2 - 1.5 8.9 7.2 0.72 10.0 2.9 2.3 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain zinc_ribbon_15 PF17032.5 CDS33826.2 - 2.6 8.8 13.8 3.4 8.5 4.9 3.3 2 1 2 4 4 3 0 zinc-ribbon family zf-C2H2_6 PF13912.6 CDS33826.2 - 2.8 8.0 7.9 3.3 7.8 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_4 PF14570.6 CDS33826.2 - 4.1 7.3 11.9 0.13 12.1 1.5 3.0 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-BED PF02892.15 CDS33826.2 - 5.4 7.1 11.4 0.48 10.5 0.4 3.4 2 1 1 3 3 3 0 BED zinc finger zf-Sec23_Sec24 PF04810.15 CDS33826.2 - 6.5 6.9 20.5 1.5 8.9 1.0 4.8 3 1 2 5 5 5 0 Sec23/Sec24 zinc finger WD40 PF00400.32 CDS33827.1 - 1e-16 61.0 21.6 0.00033 21.4 0.9 6.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Pkinase PF00069.25 CDS33829.1 - 4.9e-42 144.1 0.0 6.2e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33829.1 - 3.6e-28 98.6 0.0 4.1e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CDS33829.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDS33829.1 - 0.0039 16.6 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDS33829.1 - 0.0061 15.4 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDS33829.1 - 0.0065 15.5 0.1 0.0085 15.1 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CDS33829.1 - 0.025 14.5 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDS33829.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.3 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 CDS33829.1 - 0.04 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cadherin PF00028.17 CDS33834.1 - 1.8e-61 204.6 0.0 2.1e-13 50.5 0.0 8.0 7 2 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CDS33834.1 - 0.00041 20.1 0.0 0.28 11.1 0.0 3.7 3 0 0 3 3 3 1 Cadherin-like Cadherin_3 PF16184.5 CDS33834.1 - 0.0012 18.8 13.9 3.5 7.7 0.1 5.9 6 0 0 6 6 6 3 Cadherin-like AAA_18 PF13238.6 CDS33836.1 - 2.4e-28 99.2 0.1 5.4e-28 98.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDS33836.1 - 9.4e-06 26.1 0.0 2.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDS33836.1 - 2.2e-05 24.8 0.0 8.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 CDS33836.1 - 4e-05 23.5 0.1 0.00012 21.9 0.0 1.8 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CDS33836.1 - 4.5e-05 23.9 0.1 0.00024 21.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 CDS33836.1 - 5.7e-05 23.4 0.1 0.0001 22.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDS33836.1 - 0.00013 22.0 0.1 0.0005 20.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CDS33836.1 - 0.00018 21.7 0.0 0.00027 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDS33836.1 - 0.00038 20.9 0.0 0.00038 20.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CDS33836.1 - 0.00057 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CDS33836.1 - 0.00073 19.8 0.9 0.0032 17.7 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDS33836.1 - 0.0023 17.9 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDS33836.1 - 0.0024 17.6 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 CDS33836.1 - 0.0029 17.1 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATPase_2 PF01637.18 CDS33836.1 - 0.0042 17.0 0.1 0.017 15.0 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CDS33836.1 - 0.0043 16.8 0.6 0.0077 16.0 0.6 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CDS33836.1 - 0.0068 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 NTPase ADK PF00406.22 CDS33836.1 - 0.011 15.9 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase SKI PF01202.22 CDS33836.1 - 0.013 15.6 0.2 0.046 13.8 0.0 1.9 2 1 1 3 3 3 0 Shikimate kinase NACHT PF05729.12 CDS33836.1 - 0.013 15.4 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin2 PF13189.6 CDS33836.1 - 0.014 15.6 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_3 PF07726.11 CDS33836.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CDS33836.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CDS33836.1 - 0.022 14.0 0.2 0.029 13.6 0.2 1.6 1 1 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 CDS33836.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 CDS33836.1 - 0.027 14.3 0.2 0.099 12.5 0.0 1.9 1 1 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 CDS33836.1 - 0.037 13.3 0.1 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 CDS33836.1 - 0.043 13.2 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 KaiC cobW PF02492.19 CDS33836.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CDS33836.1 - 0.077 13.0 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CDS33836.1 - 0.088 12.5 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 CDS33836.1 - 0.12 12.8 0.2 0.15 12.5 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Tho2 PF11262.8 CDS33837.1 - 5.8e-91 304.8 2.6 1.2e-90 303.8 2.6 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 CDS33837.1 - 4.8e-81 273.3 0.2 2.7e-51 175.0 0.1 3.3 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 CDS33837.1 - 1.4e-22 79.5 0.2 1.9e-21 75.9 0.0 2.7 2 0 0 2 2 2 1 Transcription- and export-related complex subunit nsp7 PF08716.10 CDS33837.1 - 0.15 12.7 1.7 0.43 11.3 0.2 2.5 1 1 1 2 2 2 0 nsp7 replicase Tox-ODYAM1 PF15642.6 CDS33837.1 - 2.3 7.1 4.9 1.2 8.0 0.3 2.2 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus YscO PF07321.12 CDS33837.1 - 3 7.8 10.6 0.6 10.1 2.2 3.3 3 0 0 3 3 3 0 Type III secretion protein YscO Ribosomal_S30 PF04758.14 CDS33838.1 - 2.6e-28 98.0 7.5 3.4e-28 97.6 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 DUF3408 PF11888.8 CDS33838.1 - 0.75 9.9 2.4 2.1 8.5 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3408) UDG PF03167.19 CDS33839.2 - 3.2e-23 82.4 0.1 1e-22 80.8 0.1 1.9 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Prefoldin PF02996.17 CDS33840.1 - 5.6e-12 45.6 0.1 1.2e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 CDS33840.1 - 7.8 6.8 9.2 0.24 11.7 0.9 2.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil SHS2_Rpb7-N PF03876.17 CDS33841.1 - 5.7e-17 61.8 0.0 8.9e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDS33841.1 - 3.1e-13 49.9 0.6 6.3e-13 48.9 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 CDS33841.1 - 0.0006 20.1 0.2 0.00093 19.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Arrestin_N PF00339.29 CDS33842.1 - 2.2e-28 99.2 0.0 3.8e-13 49.7 0.0 3.3 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDS33842.1 - 9.5e-25 87.6 0.0 2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-RING_2 PF13639.6 CDS33843.1 - 6.3e-09 36.0 7.9 1.1e-08 35.2 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDS33843.1 - 1e-08 34.7 4.6 1.9e-08 33.9 4.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDS33843.1 - 1.8e-05 24.5 7.4 3.3e-05 23.6 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS33843.1 - 8.5e-05 22.3 6.2 0.00017 21.4 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDS33843.1 - 0.00021 21.5 9.2 0.0012 19.0 9.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS33843.1 - 0.0022 17.9 4.8 0.0036 17.2 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDS33843.1 - 0.0059 16.2 3.4 0.01 15.4 3.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CDS33843.1 - 0.0063 16.5 6.7 0.015 15.3 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 CDS33843.1 - 0.059 13.5 2.7 0.12 12.5 2.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CDS33843.1 - 0.82 9.9 6.1 1.9 8.6 6.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CDS33843.1 - 1.1 9.3 3.8 4.2 7.5 3.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDS33843.1 - 2 8.4 6.5 4.9 7.1 6.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CH PF00307.31 CDS33844.1 - 9.2e-45 151.3 0.3 1.8e-21 76.4 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 CDS33844.1 - 2.1e-36 124.6 26.5 7.6e-18 64.9 0.1 4.6 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.10 CDS33844.1 - 1.3e-16 60.4 0.1 6.5e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CDS33844.1 - 6.7e-09 34.7 0.2 3.8e-05 22.9 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDS33844.1 - 7.1e-09 36.0 0.3 7.1e-09 36.0 0.3 3.9 4 1 1 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS33844.1 - 1.4e-07 30.8 1.3 9.4e-05 22.0 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 CDS33844.1 - 6.8e-07 29.0 0.0 5.6e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_8 PF13833.6 CDS33844.1 - 2.1e-05 24.3 2.5 0.054 13.4 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain pair Cyclase_polyket PF04673.12 CDS33844.1 - 0.044 14.0 1.2 0.96 9.7 0.0 3.5 2 1 1 3 3 3 0 Polyketide synthesis cyclase Helicase_C_2 PF13307.6 CDS33845.1 - 8.1e-51 172.6 0.0 4e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDS33845.1 - 2e-34 118.8 0.1 7.4e-34 116.9 0.1 2.0 2 0 0 2 2 2 1 DEAD_2 AAA_22 PF13401.6 CDS33845.1 - 0.0083 16.4 0.1 1.3 9.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 CDS33845.1 - 0.02 14.7 0.0 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 CDS33845.1 - 0.04 13.9 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3696 PF12476.8 CDS33846.1 - 0.13 12.7 0.1 13 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) DUF3169 PF11368.8 CDS33852.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) CENP-T_C PF15511.6 CDS33855.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDS33855.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDS33855.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CDS33855.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS33855.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS33855.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDS33855.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDS33855.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 CDS33856.1 - 1.6e-21 75.7 1.3 2.6e-21 75.0 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CDS33856.1 - 3.2e-15 56.6 0.0 4.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS33856.1 - 1.9e-05 24.8 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDS33857.2 - 1.9e-05 25.0 0.1 2.6e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MOZART1 PF12554.8 CDS33858.1 - 2e-16 59.5 0.3 2.4e-16 59.2 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zf-SNAP50_C PF12251.8 CDS33859.1 - 1.2e-51 175.2 1.0 1.5e-51 174.9 0.1 1.6 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal Glyco_transf_8 PF01501.20 CDS33859.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 SH3_2 PF07653.17 CDS33861.1 - 6.3e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS33861.1 - 2.2e-06 27.2 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS33861.1 - 2.7e-06 27.1 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain eIF-3c_N PF05470.12 CDS33862.1 - 3.1e-165 550.9 15.6 4.2e-165 550.4 15.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDS33862.1 - 1.2e-08 35.4 1.0 6e-08 33.1 0.0 2.8 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CDS33862.1 - 0.062 13.4 0.6 9.6 6.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-T_C PF15511.6 CDS33863.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDS33863.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDS33863.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CDS33863.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDS33863.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDS33863.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CDS33863.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CDS33863.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) zf-RING_2 PF13639.6 CDS33864.1 - 3.1e-05 24.2 4.0 3.1e-05 24.2 4.0 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDS33864.1 - 0.038 14.0 3.2 0.038 14.0 3.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-B_box PF00643.24 CDS33864.1 - 0.041 14.0 5.3 0.041 14.0 5.3 2.8 2 1 1 3 3 3 0 B-box zinc finger zf-RING-like PF08746.11 CDS33864.1 - 0.051 13.9 1.2 0.051 13.9 1.2 2.1 1 1 1 2 2 2 0 RING-like domain LNS2 PF08235.13 CDS33865.1 - 4.7e-89 297.7 0.0 7.5e-89 297.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CDS33865.1 - 1.2e-29 102.2 0.0 5.5e-29 100.1 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CDS33865.1 - 4.5e-27 94.1 0.0 9.3e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain ACBP PF00887.19 CDS33865.1 - 2.5e-24 85.3 0.1 5.2e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 CDS33865.1 - 7.5e-20 70.7 1.8 6.1e-11 42.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33865.1 - 1.1e-12 48.4 0.0 8.1e-07 29.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CDS33865.1 - 3.2e-12 46.3 0.8 3.5e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDS33865.1 - 3.5e-12 45.4 0.1 7.9e-07 28.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CDS33865.1 - 1.5e-11 44.6 0.0 1.3e-05 25.6 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WRNPLPNID PF15017.6 CDS33865.1 - 0.031 15.2 0.0 0.094 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box gag-asp_proteas PF13975.6 CDS33867.1 - 0.01 16.4 0.0 0.057 14.0 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS33867.1 - 0.01 16.5 0.0 0.033 14.8 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 CDS33867.1 - 0.067 13.5 0.0 0.36 11.2 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Nucleos_tra2_C PF07662.13 CDS33868.1 - 4.6e-70 235.7 8.2 1.4e-69 234.1 8.2 1.9 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CDS33868.1 - 1.5e-19 70.3 1.5 1.5e-19 70.3 1.5 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CDS33868.1 - 0.00051 20.3 6.8 0.00051 20.3 6.8 2.8 2 1 0 2 2 2 1 Nucleoside recognition DUF443 PF04276.12 CDS33868.1 - 0.051 13.4 0.5 0.051 13.4 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Nucleos_tra2_C PF07662.13 CDS33869.1 - 3.4e-69 232.8 4.7 9.7e-69 231.4 4.7 1.8 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CDS33869.1 - 3.5e-19 69.2 1.7 3.5e-19 69.2 1.7 3.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus DUF4220 PF13968.6 CDS33869.1 - 0.029 13.8 0.3 0.11 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF1449 PF07290.11 CDS33869.1 - 0.27 10.8 6.5 0.12 11.9 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) DUF3099 PF11298.8 CDS33869.1 - 2.1 8.5 4.8 11 6.2 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) Orf78 PF06024.12 CDS33869.1 - 3 8.2 5.6 0.61 10.4 1.0 2.3 2 1 0 2 2 2 0 Orf78 (ac78) Ras PF00071.22 CDS33870.2 - 5.5e-20 71.6 0.0 6.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS33870.2 - 0.00031 20.9 0.1 0.0011 19.2 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF3421 PF11901.8 CDS33871.1 - 1.2e-38 131.7 4.8 6.4e-37 126.1 2.5 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) RRM_1 PF00076.22 CDS33872.1 - 8.7e-09 35.1 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Clat_adaptor_s PF01217.20 CDS33873.1 - 2.8e-56 189.4 0.7 3.2e-56 189.2 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Na_H_Exchanger PF00999.21 CDS33874.1 - 1e-54 185.8 35.8 7e-52 176.5 32.1 2.9 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Myb_DNA-bind_2 PF08914.11 CDS33876.1 - 8.5e-06 25.9 0.1 2.1e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 CDS33876.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain G6PD_C PF02781.16 CDS33877.1 - 1.4e-110 369.1 0.0 1.9e-110 368.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CDS33877.1 - 8.7e-60 202.4 0.0 1.5e-59 201.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain EF_TS PF00889.19 CDS33878.1 - 4.1e-22 78.8 0.1 1e-16 61.2 0.0 2.7 1 1 1 2 2 2 2 Elongation factor TS HLH PF00010.26 CDS33880.1 - 3.9e-14 52.3 0.0 8.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RBR PF17208.3 CDS33880.1 - 0.061 14.0 3.8 0.28 11.9 3.8 2.1 1 0 0 1 1 1 0 RNA binding Region Scramblase PF03803.15 CDS33881.1 - 5.1e-18 65.2 0.0 6.7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase EF-hand_7 PF13499.6 CDS33882.1 - 1.9e-18 66.7 8.9 4e-10 40.0 2.4 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS33882.1 - 3e-18 63.9 7.6 3.4e-06 26.2 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDS33882.1 - 4.7e-18 63.5 4.3 9.3e-05 22.1 0.0 4.7 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDS33882.1 - 3e-12 46.2 10.9 4.8e-07 29.5 1.0 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDS33882.1 - 1.8e-10 39.8 9.1 0.0027 17.1 0.0 4.5 4 0 0 4 4 4 3 EF hand p25-alpha PF05517.12 CDS33882.1 - 3.2e-05 24.2 0.3 0.00026 21.2 0.4 2.1 1 1 1 2 2 2 1 p25-alpha SPARC_Ca_bdg PF10591.9 CDS33882.1 - 0.014 15.7 0.1 1.9 8.8 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDS33882.1 - 0.057 13.3 0.5 11 5.9 0.1 2.1 1 1 1 2 2 2 0 Caleosin related protein EF-hand_11 PF08976.11 CDS33882.1 - 0.062 14.2 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Pkip-1 PF06878.11 CDS33882.1 - 0.077 13.1 0.3 0.15 12.2 0.2 1.6 2 0 0 2 2 2 0 Pkip-1 protein ATPgrasp_N PF18130.1 CDS33882.1 - 0.1 13.1 0.0 1.7 9.3 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp N-terminal domain FANC_SAP PF18081.1 CDS33882.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain adh_short PF00106.25 CDS33883.1 - 3.1e-33 114.9 0.0 3.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDS33883.1 - 1.4e-17 64.0 0.0 1.9e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDS33883.1 - 2.5e-07 30.8 0.0 9.4e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CDS33883.1 - 0.045 14.0 0.0 0.083 13.2 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDS33883.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDS33883.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 CDS33883.1 - 0.093 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 CDS33883.1 - 0.099 13.2 0.0 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DIX PF00778.17 CDS33884.1 - 8.9e-33 112.0 0.0 1.9e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 CDS33884.1 - 3e-21 75.9 0.2 6.7e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 CDS33884.1 - 3.7e-05 23.7 0.7 0.00018 21.5 0.3 2.5 2 0 0 2 2 2 1 Axin beta-catenin binding domain SPARC_Ca_bdg PF10591.9 CDS33885.1 - 0.00023 21.5 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 CDS33885.1 - 0.00059 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CDS33885.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EB PF01683.18 CDS33885.1 - 3.4 8.0 15.9 0.1 12.9 2.3 2.8 3 0 0 3 3 3 0 EB module zf-NOSIP PF15906.5 CDS33886.1 - 1.1e-36 124.8 0.5 2.1e-36 123.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein PLDc_2 PF13091.6 CDS33886.1 - 1.5e-13 50.7 0.0 2.5e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain U-box PF04564.15 CDS33886.1 - 6.6e-08 32.6 0.1 0.019 15.1 0.0 2.7 2 0 0 2 2 2 2 U-box domain PLDc PF00614.22 CDS33886.1 - 1e-07 31.8 3.1 7.6e-05 22.7 0.1 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif Rtf2 PF04641.12 CDS33886.1 - 1.8e-07 30.8 2.1 0.00024 20.6 0.0 2.6 2 1 1 3 3 3 2 Rtf2 RING-finger zf-Nse PF11789.8 CDS33886.1 - 0.0069 16.2 0.3 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF4543 PF15076.6 CDS33886.1 - 0.14 12.3 1.1 0.34 11.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) SKA1 PF07160.12 CDS33887.1 - 0.25 11.2 5.8 0.4 10.5 5.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SAC3_GANP PF03399.16 CDS33888.1 - 4.5e-38 131.3 8.0 3.2e-18 66.1 0.1 4.4 2 2 0 2 2 2 2 SAC3/GANP family HTH_18 PF12833.7 CDS33888.1 - 0.034 14.4 0.6 4.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain RRM_1 PF00076.22 CDS33889.1 - 2.5e-31 107.3 0.1 2.7e-16 59.1 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 CDS33889.1 - 1.2e-05 25.5 16.7 1.9e-05 24.8 16.7 1.2 1 0 0 1 1 1 1 Fruit fly transformer protein Apis_Csd PF11671.8 CDS33889.1 - 0.00014 21.9 2.2 0.0003 20.8 2.2 1.5 1 0 0 1 1 1 1 Complementary sex determiner protein RRM_7 PF16367.5 CDS33889.1 - 0.00032 20.7 0.0 0.033 14.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif Apt1 PF10351.9 CDS33889.1 - 0.11 11.3 2.4 0.15 10.9 2.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TT_ORF1 PF02956.14 CDS33889.1 - 0.39 9.4 14.5 0.55 8.8 14.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 RSRP PF17069.5 CDS33889.1 - 3.2 7.2 29.0 4.9 6.6 29.0 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 CDS33889.1 - 6.1 5.0 13.8 8.6 4.5 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ANAPC4_WD40 PF12894.7 CDS33890.1 - 0.00011 22.4 0.2 0.55 10.6 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDS33890.1 - 0.00046 20.9 9.2 1.4 9.9 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SPX PF03105.19 CDS33891.1 - 6.7 6.5 10.6 11 5.8 10.6 1.4 1 0 0 1 1 1 0 SPX domain RabGAP-TBC PF00566.18 CDS33892.1 - 9.6e-27 94.0 0.0 2.1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CDS33892.1 - 1.1e-11 44.6 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS33892.1 - 2.6e-11 43.3 0.0 4.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 CDS33892.1 - 0.1 13.2 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Ank PF00023.30 CDS33894.1 - 5e-07 29.9 2.7 9.1e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CDS33894.1 - 6.3e-07 29.8 0.3 1.3e-06 28.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33894.1 - 8.9e-07 29.4 0.1 1.4e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS33894.1 - 4e-06 27.0 1.0 8.2e-06 26.0 0.8 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS33894.1 - 0.00014 22.0 2.3 0.047 14.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeat fn3 PF00041.21 CDS33898.1 - 1.7e-18 66.8 0.3 5.9e-08 32.9 0.4 2.6 2 1 0 2 2 2 2 Fibronectin type III domain Interfer-bind PF09294.10 CDS33898.1 - 0.01 16.1 0.3 2.4 8.5 0.0 2.7 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III STI1 PF17830.1 CDS33899.1 - 3.1e-06 27.0 0.5 2.2e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 STI1 domain SIL1 PF16782.5 CDS33899.1 - 0.0023 17.2 1.6 0.0071 15.6 0.2 1.9 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 AAA_8 PF12780.7 CDS33899.1 - 0.015 14.7 0.4 0.02 14.2 0.3 1.3 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 Glyco_trans_1_2 PF13524.6 CDS33899.1 - 0.093 13.1 1.9 1.7 9.1 0.1 2.5 1 1 1 2 2 2 0 Glycosyl transferases group 1 ECH_2 PF16113.5 CDS33899.1 - 0.15 11.5 1.8 0.17 11.3 1.8 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF760 PF05542.11 CDS33899.1 - 0.23 11.9 1.1 14 6.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF760) Inhibitor_I9 PF05922.16 CDS33902.1 - 0.018 15.7 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF3439 PF11921.8 CDS33903.1 - 0.0083 16.1 5.5 0.0083 16.1 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) B5 PF03484.15 CDS33903.1 - 0.015 15.6 0.0 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 tRNA synthetase B5 domain SSP160 PF06933.11 CDS33903.1 - 0.088 11.0 11.5 0.15 10.2 11.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Vitellogenin_N PF01347.22 CDS33903.1 - 0.15 10.4 1.1 7.3 4.9 0.0 2.2 2 1 0 2 2 2 0 Lipoprotein amino terminal region FliG_C PF01706.16 CDS33903.1 - 0.22 11.7 2.2 5.3 7.3 0.1 3.5 3 1 1 4 4 4 0 FliG C-terminal domain DUF5582 PF17819.1 CDS33903.1 - 0.38 11.2 2.9 14 6.1 0.0 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5582) ALG3 PF05208.13 CDS33906.1 - 2.6e-81 273.8 14.8 3.1e-68 230.8 10.3 2.1 1 1 1 2 2 2 2 ALG3 protein SMP_C2CD2L PF18696.1 CDS33908.1 - 0.032 14.1 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Synaptotagmin-like, mitochondrial and lipid-binding domain MH2 PF03166.14 CDS33909.1 - 1.3e-73 247.2 0.3 1.9e-73 246.7 0.3 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CDS33909.1 - 1e-40 138.1 1.2 2.7e-40 136.7 1.2 1.8 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.9 CDS33909.1 - 0.038 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-regulatory factor 3 EGF PF00008.27 CDS33911.1 - 5e-15 55.5 109.2 0.0018 18.5 6.5 9.0 8 0 0 8 8 8 6 EGF-like domain EGF_CA PF07645.15 CDS33911.1 - 1.5e-12 47.5 125.8 8.7e-09 35.4 7.9 10.2 8 2 2 10 10 10 6 Calcium-binding EGF domain cEGF PF12662.7 CDS33911.1 - 4.8e-12 45.6 74.0 7e-05 22.7 0.5 10.2 11 0 0 11 11 11 7 Complement Clr-like EGF-like hEGF PF12661.7 CDS33911.1 - 1.3e-11 44.7 123.0 0.0035 17.9 5.8 10.7 10 0 0 10 10 10 7 Human growth factor-like EGF EGF_2 PF07974.13 CDS33911.1 - 2.9e-05 24.3 14.3 2.9e-05 24.3 14.3 9.9 10 0 0 10 10 10 5 EGF-like domain FXa_inhibition PF14670.6 CDS33911.1 - 0.00017 21.8 106.5 0.0041 17.4 6.3 8.7 8 0 0 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CDS33911.1 - 0.0013 18.9 0.5 0.0013 18.9 0.5 9.5 8 1 0 8 8 8 5 EGF domain Plasmod_Pvs28 PF06247.11 CDS33911.1 - 0.0027 18.0 15.9 0.0076 16.5 4.0 10.2 9 2 0 9 9 9 4 Pvs28 EGF domain EGF_Tenascin PF18720.1 CDS33911.1 - 0.0095 16.0 8.2 0.0095 16.0 8.2 8.3 8 3 1 9 9 9 1 Tenascin EGF domain EGF_MSP1_1 PF12946.7 CDS33911.1 - 0.013 15.5 3.8 0.013 15.5 3.8 9.1 9 0 0 9 9 9 0 MSP1 EGF domain 1 Ion_trans_N PF08412.10 CDS33912.1 - 8.3e-25 86.1 0.7 2.1e-24 84.9 0.7 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal Ion_trans PF00520.31 CDS33912.1 - 7e-24 84.4 15.8 3.8e-23 82.0 15.8 1.9 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CDS33912.1 - 3.1e-20 72.0 0.0 7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CDS33912.1 - 0.0013 18.6 0.1 0.0035 17.3 0.1 1.7 1 0 0 1 1 1 1 Ion channel Myb_DNA-binding PF00249.31 CDS33913.1 - 5.8e-05 23.2 0.0 0.00084 19.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ion_trans PF00520.31 CDS33914.2 - 9.5e-06 25.0 2.9 1.2e-05 24.6 2.9 1.1 1 0 0 1 1 1 1 Ion transport protein GCP_C_terminal PF04130.13 CDS33915.1 - 1.4e-17 64.2 3.6 4.6e-17 62.5 1.1 2.7 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDS33915.1 - 5.5e-12 45.9 6.6 8.1e-12 45.4 3.9 2.4 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal HLH PF00010.26 CDS33918.1 - 7.7e-12 45.0 4.1 1.5e-11 44.1 4.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Basic PF01586.16 CDS33918.1 - 2e-11 44.9 1.6 8.4e-11 42.9 1.6 2.2 1 0 0 1 1 1 1 Myogenic Basic domain DUF680 PF05079.12 CDS33918.1 - 6.7 7.5 8.6 0.86 10.3 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF680) ABC_tran PF00005.27 CDS33919.1 - 1e-37 129.7 0.0 1.8e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CDS33919.1 - 1.6e-11 43.8 6.9 4.4e-11 42.4 6.9 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CDS33919.1 - 1.4e-10 41.0 3.6 0.0032 16.9 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDS33919.1 - 3.8e-09 36.8 7.0 0.29 10.9 0.0 4.1 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CDS33919.1 - 2.4e-08 33.5 3.4 2.4e-08 33.5 3.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 CDS33919.1 - 2e-06 28.3 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDS33919.1 - 3.2e-06 27.7 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDS33919.1 - 7.7e-06 26.2 0.0 0.0028 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CDS33919.1 - 3.4e-05 23.7 0.0 0.27 10.9 0.0 2.8 4 0 0 4 4 2 2 AAA ATPase domain Fer4_6 PF12837.7 CDS33919.1 - 5.2e-05 23.1 3.2 5.2e-05 23.1 3.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CDS33919.1 - 8.1e-05 22.6 0.1 0.25 11.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase Fer4_2 PF12797.7 CDS33919.1 - 0.00012 22.0 0.7 0.00012 22.0 0.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 CDS33919.1 - 0.00019 21.1 0.6 0.73 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 CDS33919.1 - 0.00042 20.5 0.0 0.87 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Fer4_21 PF14697.6 CDS33919.1 - 0.00066 19.8 12.8 0.0024 18.0 12.9 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 CDS33919.1 - 0.00074 19.5 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 CDS33919.1 - 0.0011 19.0 0.1 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_10 PF13237.6 CDS33919.1 - 0.0035 17.4 1.8 0.0035 17.4 1.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDS33919.1 - 0.0037 17.4 12.6 0.0076 16.4 12.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CDS33919.1 - 0.0038 17.6 0.6 1.2 9.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 CDS33919.1 - 0.005 16.6 1.4 0.42 10.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CDS33919.1 - 0.0052 17.4 12.1 0.0066 17.0 2.3 2.0 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_23 PF13476.6 CDS33919.1 - 0.0053 17.3 4.3 0.055 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDS33919.1 - 0.0099 15.4 0.0 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CDS33919.1 - 0.013 15.4 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 CDS33919.1 - 0.016 14.8 3.1 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CDS33919.1 - 0.02 15.1 0.2 3.3 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDS33919.1 - 0.023 15.2 0.0 4.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDS33919.1 - 0.045 13.5 0.2 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CDS33919.1 - 0.047 13.9 0.0 11 6.4 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CDS33919.1 - 0.077 12.2 0.0 4.4 6.4 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain Fer4_8 PF13183.6 CDS33919.1 - 0.081 13.4 0.2 0.081 13.4 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 CDS33919.1 - 0.085 12.9 0.1 11 6.1 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 CDS33919.1 - 0.097 12.3 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase SCHIP-1 PF10148.9 CDS33919.1 - 0.13 11.9 0.3 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 MukB PF04310.12 CDS33919.1 - 0.13 12.1 0.6 16 5.2 0.1 2.7 3 0 0 3 3 2 0 MukB N-terminal AAA_14 PF13173.6 CDS33919.1 - 0.14 12.2 1.0 9.1 6.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 CDS33919.1 - 0.15 12.1 1.0 3.2 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) VirE PF05272.11 CDS33919.1 - 0.15 11.7 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_19 PF13245.6 CDS33919.1 - 0.21 11.9 0.2 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CDS33919.1 - 0.39 10.9 1.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CDS33919.1 - 0.4 10.6 1.6 12 5.8 0.1 2.8 2 0 0 2 2 2 0 NTPase Fer4_16 PF13484.6 CDS33919.1 - 1.1 10.3 14.0 0.13 13.3 2.5 2.6 1 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 CDS33919.1 - 1.7 9.4 15.8 0.14 12.7 3.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 CDS33919.1 - 3.1 8.4 10.5 0.12 13.0 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain ATP-synt_C PF00137.21 CDS33920.1 - 1.1e-33 115.3 36.8 2.2e-21 75.9 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TctB PF07331.11 CDS33920.1 - 1.7 8.9 16.8 31 4.8 16.8 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Zip PF02535.22 CDS33921.1 - 2.1e-39 135.7 22.9 4.8e-30 104.9 15.5 3.3 2 2 1 3 3 3 2 ZIP Zinc transporter DUF4719 PF15843.5 CDS33921.1 - 0.025 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DctQ PF04290.12 CDS33921.1 - 0.25 11.3 9.6 0.27 11.2 0.0 3.2 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component PHD PF00628.29 CDS33922.1 - 0.00013 21.8 3.0 0.00035 20.4 3.0 1.8 1 1 0 1 1 1 1 PHD-finger UPF0242 PF06785.11 CDS33923.2 - 0.00017 21.7 1.8 0.0003 21.0 1.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 CDS33923.2 - 0.0038 17.4 2.2 0.0062 16.8 1.4 1.8 2 0 0 2 2 2 1 ABC transporter C-terminal domain Gp-FAR-1 PF05823.12 CDS33923.2 - 0.043 14.2 0.8 0.076 13.4 0.8 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FapA PF03961.13 CDS33923.2 - 0.051 12.2 0.3 0.063 11.9 0.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A NAD_Gly3P_dh_C PF07479.14 CDS33923.2 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Spc7 PF08317.11 CDS33923.2 - 0.097 11.5 6.3 0.15 10.9 6.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 CDS33923.2 - 0.4 9.9 3.9 0.75 9.0 3.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.11 CDS33923.2 - 2.1 8.9 6.0 38 4.9 6.0 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF16 PF01519.16 CDS33923.2 - 7 7.2 10.3 12 6.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliD_N PF02465.18 CDS33923.2 - 7 7.4 14.2 1.1 10.0 0.3 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SDF PF00375.18 CDS33925.2 - 2.1e-52 178.5 27.7 4.9e-43 147.6 20.5 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family UTP25 PF06862.12 CDS33927.1 - 3.1e-99 332.9 0.1 6.7e-64 216.4 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CDS33927.1 - 0.00014 21.7 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase UCH PF00443.29 CDS33928.1 - 3.6e-68 229.9 0.1 4.5e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDS33928.1 - 3.3e-12 46.8 0.0 9.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 CDS33928.1 - 2.3e-11 43.9 0.0 0.00042 20.0 0.0 3.3 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Lac_bphage_repr PF06543.12 CDS33928.1 - 0.13 12.3 0.2 57 3.8 0.0 3.4 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Ank_4 PF13637.6 CDS33929.1 - 4.2e-17 62.3 1.7 9.1e-11 42.1 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS33929.1 - 5.8e-16 58.8 0.3 8e-16 58.4 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDS33929.1 - 2.1e-14 53.2 0.5 4.2e-06 27.0 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CDS33929.1 - 6.7e-12 44.5 0.6 5.6e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CDS33929.1 - 5.6e-10 39.3 0.4 3.3e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) LRR_8 PF13855.6 CDS33931.1 - 0.17 11.7 2.7 2.7 7.8 0.3 3.6 2 1 2 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 CDS33931.1 - 1.1 9.5 4.8 4.2 7.7 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Transposase_1 PF01359.18 CDS33933.1 - 0.017 14.9 0.1 0.038 13.8 0.1 1.6 1 0 0 1 1 1 0 Transposase (partial DDE domain) RT_RNaseH_2 PF17919.1 CDS33934.1 - 0.00036 20.5 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS33934.1 - 0.0094 16.1 0.3 0.035 14.3 0.3 2.1 1 1 0 1 1 1 1 Integrase core domain DUF4539 PF15072.6 CDS33936.1 - 1.9e-24 85.5 0.2 3.5e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) tRNA_anti-codon PF01336.25 CDS33936.1 - 0.079 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain fn3 PF00041.21 CDS33937.1 - 2.9e-22 78.8 0.9 1.1e-09 38.5 0.7 4.1 4 0 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CDS33937.1 - 3.9e-09 37.0 0.1 0.014 15.9 0.0 3.8 4 0 0 4 4 4 3 Purple acid Phosphatase, N-terminal domain WAP PF00095.21 CDS33937.1 - 0.017 15.5 7.8 0.017 15.5 7.8 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.10 CDS33937.1 - 0.027 14.8 0.0 1.7 9.0 0.0 3.3 4 0 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III Rad9 PF04139.13 CDS33938.1 - 1.1e-62 211.7 7.0 1.4e-62 211.4 7.0 1.1 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.18 CDS33938.1 - 0.02 14.6 1.7 0.12 12.0 0.2 2.2 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Hus1 PF04005.12 CDS33938.1 - 0.2 10.7 3.0 0.41 9.7 3.0 1.5 1 1 0 1 1 1 0 Hus1-like protein Innexin PF00876.18 CDS33939.1 - 4.9e-112 374.7 5.2 7.2e-112 374.2 5.2 1.2 1 1 0 1 1 1 1 Innexin Vpu PF00558.19 CDS33939.1 - 0.92 9.3 0.0 0.92 9.3 0.0 2.5 3 0 0 3 3 3 0 Vpu protein SPT6_acidic PF14632.6 CDS33940.1 - 0.083 13.5 0.0 0.095 13.3 0.0 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 RT_RNaseH_2 PF17919.1 CDS33943.1 - 1.9e-21 75.9 0.1 3.5e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS33943.1 - 2.1e-20 72.9 0.0 4.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase BORCS7 PF16088.5 CDS33943.1 - 0.0055 16.9 1.1 0.011 16.0 1.1 1.4 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Fz PF01392.22 CDS33945.2 - 5.3e-27 94.6 2.1 1.1e-26 93.7 2.1 1.5 1 0 0 1 1 1 1 Fz domain TIMP PF00965.17 CDS33945.2 - 0.00039 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase Mating_C PF12737.7 CDS33945.2 - 0.062 12.5 9.9 0.094 11.9 9.9 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 IMD PF08397.11 CDS33945.2 - 0.09 12.1 1.6 0.15 11.4 1.6 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Tim17 PF02466.19 CDS33946.1 - 2.3e-25 89.1 4.9 3.4e-25 88.6 4.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family OCRE PF17780.1 CDS33947.1 - 7.2e-15 54.7 5.5 1.2e-14 54.0 5.5 1.4 1 0 0 1 1 1 1 OCRE domain RRM_1 PF00076.22 CDS33947.1 - 6.1e-14 51.6 0.2 2.9e-07 30.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 CDS33947.1 - 9.8e-14 51.0 2.5 2.6e-13 49.6 2.5 1.8 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 CDS33947.1 - 1.6e-07 30.5 3.2 3.6e-07 29.4 3.2 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 CDS33947.1 - 4e-07 30.0 1.5 4e-07 30.0 1.5 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 CDS33947.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RED_N PF07808.13 CDS33947.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region LsmAD PF06741.13 CDS33947.1 - 0.7 10.5 4.7 0.53 10.9 1.8 2.3 2 0 0 2 2 2 0 LsmAD domain PHC2_SAM_assoc PF16616.5 CDS33947.1 - 7.8 7.3 12.0 0.85 10.5 6.9 2.0 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF4337 PF14235.6 CDS33947.1 - 9.8 6.3 8.7 21 5.2 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ABA_GPCR PF12430.8 CDS33948.1 - 2.1e-39 135.2 12.1 2.1e-39 135.2 12.1 1.5 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CDS33948.1 - 9.7e-15 54.4 0.0 1.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal NPCC PF08058.11 CDS33948.1 - 0.021 14.9 5.1 0.076 13.1 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore complex component Arm PF00514.23 CDS33949.2 - 1.2e-44 149.0 15.9 1.8e-05 24.6 0.0 13.5 14 0 0 14 14 14 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDS33949.2 - 7.6e-14 51.9 9.3 0.003 17.9 0.0 7.0 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 CDS33949.2 - 2.1e-07 30.6 13.7 0.14 12.5 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat KAP PF05804.12 CDS33949.2 - 8.8e-07 27.5 0.0 0.36 8.9 0.2 3.8 3 1 1 4 4 4 3 Kinesin-associated protein (KAP) RICTOR_N PF14664.6 CDS33949.2 - 1.6e-05 24.1 1.2 0.2 10.6 0.1 3.6 1 1 2 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term HEAT_EZ PF13513.6 CDS33949.2 - 0.00036 21.0 9.8 1 9.9 0.0 7.2 7 1 2 9 9 9 1 HEAT-like repeat CTNNBL PF08216.11 CDS33949.2 - 0.05 13.8 0.1 5.2 7.3 0.0 4.0 5 1 1 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear WAPL PF07814.13 CDS33949.2 - 0.16 10.7 11.2 0.36 9.6 0.0 5.1 6 1 0 7 7 7 0 Wings apart-like protein regulation of heterochromatin Cnd1 PF12717.7 CDS33949.2 - 0.28 11.2 5.5 54 3.8 0.3 4.4 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 P2X_receptor PF00864.19 CDS33950.1 - 2e-122 408.9 0.0 2.3e-122 408.6 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor G0-G1_switch_2 PF15103.6 CDS33950.1 - 0.017 15.5 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Acyl_transf_1 PF00698.21 CDS33951.1 - 2.8e-17 63.2 0.0 1.7e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 Acyl transferase domain Peptidase_M8 PF01457.16 CDS33952.1 - 2.8e-46 158.3 2.0 2.6e-45 155.1 2.0 2.0 1 1 0 1 1 1 1 Leishmanolysin ketoacyl-synt PF00109.26 CDS33953.1 - 5.2e-45 154.0 5.3 2.9e-44 151.5 0.9 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CDS33953.1 - 1.9e-26 92.4 0.1 4e-26 91.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CDS33953.1 - 0.0002 20.8 0.1 0.00038 19.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 CDS33953.1 - 0.021 15.3 0.0 0.24 11.9 0.0 2.5 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 CDS33953.1 - 0.088 12.7 0.1 16 5.4 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III VMA21 PF09446.10 CDS33954.1 - 3.9e-10 39.7 7.5 3.9e-10 39.7 7.5 1.5 2 0 0 2 2 2 1 VMA21-like domain BCHF PF07284.11 CDS33954.1 - 0.0034 17.4 1.1 0.0042 17.1 1.1 1.1 1 0 0 1 1 1 1 2-vinyl bacteriochlorophyllide hydratase (BCHF) SCAMP PF04144.13 CDS33954.1 - 0.017 15.4 3.0 0.02 15.2 3.0 1.1 1 0 0 1 1 1 0 SCAMP family DUF1772 PF08592.11 CDS33954.1 - 0.045 14.1 0.1 0.048 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RR_TM4-6 PF06459.12 CDS33954.1 - 0.1 12.4 0.5 0.13 12.0 0.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-CCCH PF00642.24 CDS33955.1 - 0.00045 20.0 16.5 0.03 14.3 5.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDS33955.1 - 0.001 19.0 15.3 0.0053 16.8 6.5 3.2 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CDS33955.1 - 0.0019 18.4 2.6 1.4 9.1 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger containing family DUF4515 PF14988.6 CDS33955.1 - 0.01 15.7 0.7 0.01 15.7 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Torus PF16131.5 CDS33955.1 - 0.053 14.2 3.2 5 7.9 0.1 3.2 2 0 0 2 2 2 0 Torus domain PBP1_TM PF14812.6 CDS33955.1 - 1.3 9.4 6.5 0.19 12.1 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRP19 PF01922.17 CDS33956.1 - 7.3e-24 84.5 0.0 9.3e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein Miga PF10265.9 CDS33957.1 - 3.3e-75 254.1 7.7 5.6e-75 253.3 5.3 2.2 1 1 1 2 2 2 1 Mitoguardin DUF948 PF06103.11 CDS33957.1 - 0.079 13.2 0.3 0.16 12.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Guanylate_cyc PF00211.20 CDS33958.2 - 3.1e-86 287.7 4.0 6.1e-49 166.1 0.3 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain FB_lectin PF07367.11 CDS33958.2 - 0.027 14.4 0.6 13 5.7 0.0 2.9 2 1 0 2 2 2 0 Fungal fruit body lectin PHD PF00628.29 CDS33959.2 - 8.6e-11 41.6 5.9 1.7e-10 40.6 5.9 1.5 1 0 0 1 1 1 1 PHD-finger Bromo_TP PF07524.13 CDS33959.2 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PHD_2 PF13831.6 CDS33959.2 - 0.0034 16.9 1.3 0.0034 16.9 1.3 2.1 2 0 0 2 2 2 1 PHD-finger Bromo_TP_like PF17027.5 CDS33959.2 - 0.053 13.7 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Histone-fold protein zf-Sec23_Sec24 PF04810.15 CDS33959.2 - 0.099 12.7 0.1 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-MIZ PF02891.20 CDS33959.2 - 0.1 12.4 4.7 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 CDS33959.2 - 0.2 12.0 5.9 0.37 11.2 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 CDS33959.2 - 0.2 11.9 0.7 0.51 10.6 0.7 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Vps36-NZF-N PF16988.5 CDS33959.2 - 0.61 9.5 4.9 3.9 6.9 0.1 3.2 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-ANAPC11 PF12861.7 CDS33959.2 - 1.7 8.7 4.3 3.5 7.7 4.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FGF PF00167.18 CDS33963.2 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor Autoind_bind PF03472.15 CDS33963.2 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Defensin_1 PF00323.19 CDS33965.1 - 0.4 11.3 4.6 58 4.4 0.0 3.2 2 1 1 3 3 3 0 Mammalian defensin ACBP PF00887.19 CDS33966.1 - 4.1e-24 84.6 2.0 4.4e-24 84.5 2.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CDS33966.1 - 0.0023 18.3 0.5 0.1 13.0 0.1 2.0 1 1 1 2 2 2 2 FERM central domain ACBP PF00887.19 CDS33967.1 - 2.5e-25 88.5 0.3 2.7e-25 88.4 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DAO PF01266.24 CDS33968.1 - 4.2e-43 148.3 0.0 5.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDS33968.1 - 0.00034 19.9 0.0 0.00083 18.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDS33968.1 - 0.0019 18.7 0.1 0.0046 17.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDS33968.1 - 0.0061 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 CDS33968.1 - 0.069 12.0 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Mqo PF06039.15 CDS33968.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Tti2 PF10521.9 CDS33969.1 - 0.033 13.7 0.5 0.24 10.9 0.2 2.3 2 0 0 2 2 2 0 Tti2 family C2 PF00168.30 CDS33970.1 - 3.2e-22 78.8 0.0 6.7e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 CDS33970.1 - 0.001 19.7 0.0 21 5.8 0.0 3.9 3 0 0 3 3 3 2 Putative heavy-metal-binding nlz1 PF12402.8 CDS33970.1 - 0.082 13.4 0.3 0.26 11.8 0.3 1.8 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF1190 PF06693.11 CDS33970.1 - 0.083 13.3 0.6 0.16 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Ig_3 PF13927.6 CDS33972.1 - 1.4e-09 38.4 0.0 3e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CDS33972.1 - 2.6e-09 37.0 0.0 4.9e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS33972.1 - 3.1e-07 30.6 0.1 1.6e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain IGFBP PF00219.18 CDS33972.1 - 3.6e-07 30.7 17.4 3.6e-07 30.7 17.4 2.1 2 1 0 2 2 2 1 Insulin-like growth factor binding protein ig PF00047.25 CDS33972.1 - 5.2e-05 23.3 0.1 0.00058 20.0 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDS33972.1 - 0.0094 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Antimicrobial10 PF08105.11 CDS33972.1 - 0.052 13.6 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Metchnikowin family RVT_1 PF00078.27 CDS33973.1 - 3.1e-11 43.2 0.2 3.9e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDS33975.1 - 1.5e-16 60.2 0.3 1.5e-16 60.2 0.3 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS33975.1 - 1.4e-10 41.3 0.0 3.7e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS33975.1 - 6.9e-10 39.2 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CDS33975.1 - 4.1e-09 36.4 3.1 9.2e-09 35.3 3.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDS33975.1 - 0.095 12.9 0.8 0.19 12.0 0.8 1.5 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 CDS33976.1 - 7.4e-22 78.0 0.4 8.9e-21 74.4 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2457 PF10446.9 CDS33976.1 - 0.19 10.8 1.4 0.23 10.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) His_Phos_1 PF00300.22 CDS33978.1 - 2.1e-32 112.4 0.0 9.3e-30 103.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LIN37 PF15306.6 CDS33979.1 - 3.9e-35 121.4 0.3 3.9e-35 121.4 0.3 1.5 2 0 0 2 2 2 1 LIN37 Peptidase_C78 PF07910.13 CDS33980.1 - 1.5e-34 119.3 0.3 1.9e-34 119.0 0.3 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CDS33980.1 - 1.5e-05 24.6 1.0 0.097 12.1 0.4 2.7 1 1 2 3 3 3 2 Peptidase family C54 NTP_transf_9 PF04248.12 CDS33980.1 - 0.014 15.3 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Arginase PF00491.21 CDS33980.1 - 0.07 12.6 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Arginase family PI3_PI4_kinase PF00454.27 CDS33981.2 - 1.8e-38 132.8 0.0 2.7e-36 125.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDS33981.2 - 3.1e-25 88.7 0.0 7.1e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Tcp10_C PF07202.13 CDS33982.1 - 5.4e-70 234.9 2.1 5.4e-70 234.9 2.1 2.7 3 0 0 3 3 3 1 T-complex protein 10 C-terminus DUF2852 PF11014.8 CDS33982.1 - 0.22 11.7 15.1 0.15 12.2 10.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) DUF4407 PF14362.6 CDS33982.1 - 1.6 8.0 14.1 3.2 7.0 14.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PT PF04886.12 CDS33983.1 - 0.093 12.3 0.6 0.093 12.3 0.6 2.3 2 0 0 2 2 2 0 PT repeat Acyltransferase PF01553.21 CDS33985.1 - 1.8e-15 56.7 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pkinase_Tyr PF07714.17 CDS33986.1 - 6e-30 104.4 0.0 3.7e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS33986.1 - 8.6e-28 97.4 0.0 5.2e-25 88.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain TGF_beta_GS PF08515.12 CDS33986.1 - 2.2e-08 33.4 2.8 5.5e-08 32.2 2.8 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 CDS33986.1 - 0.00031 19.7 0.0 0.00055 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CDS33986.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MPS-4 PF17523.2 CDS33986.1 - 8.7 6.6 8.6 1.6 8.9 1.0 2.7 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 GCS PF03074.16 CDS33987.1 - 1.9e-162 540.8 0.0 2.5e-162 540.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase CDC50 PF03381.15 CDS33988.1 - 2e-85 286.7 0.1 2.6e-85 286.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PTP_tm PF18861.1 CDS33988.1 - 0.08 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J RRM_1 PF00076.22 CDS33989.1 - 1.2e-38 130.8 0.2 4.9e-18 64.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS33989.1 - 2.7e-07 30.4 0.0 0.014 15.3 0.0 4.3 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CDS33989.1 - 4.9e-05 23.4 0.1 0.76 9.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDS33989.1 - 0.023 14.7 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif LPP20 PF02169.16 CDS33989.1 - 0.053 13.9 8.8 0.18 12.1 0.4 2.7 2 0 0 2 2 2 0 LPP20 lipoprotein ELO PF01151.18 CDS33990.1 - 5.2e-17 62.2 1.3 5.8e-17 62.1 1.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2207 PF09972.9 CDS33990.1 - 0.15 10.8 1.7 0.17 10.6 1.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nop16 PF09420.10 CDS33991.1 - 7.3e-21 75.2 3.4 9.4e-13 48.7 0.2 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 eRF1_2 PF03464.15 CDS33992.1 - 6.4e-44 149.5 0.0 9.7e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDS33992.1 - 5.5e-37 126.7 0.0 1.1e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CDS33992.1 - 1.7e-17 63.6 0.1 6.2e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 CDS33992.1 - 3.9e-08 33.7 0.0 5.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CDS33992.1 - 9.5e-07 29.2 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Actin PF00022.19 CDS33993.1 - 6.3e-108 361.0 0.0 5.2e-107 358.0 0.0 1.9 1 1 0 1 1 1 1 Actin NHL PF01436.21 CDS33993.1 - 0.91 9.7 5.9 0.13 12.4 0.6 2.2 2 0 0 2 2 2 0 NHL repeat Glyco_transf_8 PF01501.20 CDS33994.1 - 7e-11 42.2 0.0 2.7e-09 37.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CDS33994.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 CDS33994.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Fibrillarin PF01269.17 CDS33996.1 - 3.2e-100 333.9 0.0 3.8e-100 333.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CDS33996.1 - 2.2e-05 24.3 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 CDS33996.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 CDS33996.1 - 0.057 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) dCMP_cyt_deam_1 PF00383.23 CDS33997.1 - 9.8e-08 31.8 0.3 1.9e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDS33997.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 MafB19-like deaminase APOBEC2 PF18772.1 CDS33997.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 CDS33997.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 TMEM126 PF07114.11 CDS33998.1 - 3e-08 33.3 0.3 3.5e-08 33.0 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 126 zf-LITAF-like PF10601.9 CDS33998.1 - 0.13 12.6 0.5 0.13 12.6 0.5 2.6 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain zf-C4 PF00105.18 CDS33999.1 - 4.2e-20 72.0 15.0 8.3e-20 71.0 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RRM_1 PF00076.22 CDS33999.1 - 2.7e-19 68.8 0.0 4.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C1_2 PF03107.16 CDS33999.1 - 0.0031 17.8 0.7 0.0031 17.8 0.7 2.4 2 0 0 2 2 2 1 C1 domain RRM_5 PF13893.6 CDS33999.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hepatitis_core PF00906.20 CDS33999.1 - 4.4 6.8 12.7 6.9 6.2 12.7 1.3 1 0 0 1 1 1 0 Hepatitis core antigen WD40 PF00400.32 CDS34000.1 - 3.4e-05 24.5 10.6 0.00018 22.2 0.4 5.5 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34000.1 - 0.00055 20.2 0.1 0.38 11.1 0.1 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NPHI_C PF08469.10 CDS34000.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal PORR PF11955.8 CDS34001.1 - 0.0072 15.3 0.1 1.8 7.5 0.0 2.9 3 0 0 3 3 3 2 Plant organelle RNA recognition domain zf-H2C2_2 PF13465.6 CDS34002.1 - 8.7e-17 60.7 24.2 4.3e-08 33.2 2.4 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDS34002.1 - 5e-16 58.2 23.1 3.3e-07 30.4 2.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34002.1 - 1.8e-10 40.7 20.2 0.00045 20.8 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDS34002.1 - 0.0014 18.3 30.3 0.019 14.7 0.0 5.2 4 2 0 4 4 4 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CDS34002.1 - 0.0015 18.8 10.3 0.04 14.2 4.8 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDS34002.1 - 0.0027 17.4 1.4 0.0027 17.4 1.4 4.0 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-BED PF02892.15 CDS34002.1 - 0.003 17.5 17.8 0.016 15.2 0.6 4.1 3 1 1 4 4 4 2 BED zinc finger GAGA PF09237.11 CDS34002.1 - 0.0063 16.3 9.3 0.32 10.9 0.3 3.4 1 1 2 3 3 3 2 GAGA factor zf-C2H2_jaz PF12171.8 CDS34002.1 - 0.02 15.2 13.0 0.04 14.2 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 CDS34002.1 - 0.032 14.1 12.1 0.23 11.4 0.2 3.4 2 2 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-MYST PF17772.1 CDS34002.1 - 0.044 13.4 6.2 0.49 10.0 0.2 3.3 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2H2_2 PF12756.7 CDS34002.1 - 0.047 14.0 9.8 3.4 8.1 1.6 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CDS34002.1 - 0.079 13.0 0.5 0.079 13.0 0.5 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDS34002.1 - 0.25 12.0 11.2 4.4 8.0 0.7 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats ACTH_domain PF00976.18 CDS34002.1 - 0.46 10.5 2.3 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 Corticotropin ACTH domain CAP_N PF01213.19 CDS34002.1 - 0.77 9.2 3.0 2.9 7.3 3.7 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-C2HE PF16278.5 CDS34002.1 - 0.77 10.3 14.4 0.79 10.2 1.0 3.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 CDS34002.1 - 1.3 9.9 9.3 13 6.7 1.6 2.8 1 1 3 4 4 4 0 zinc-ribbon family Spt46 PF17734.1 CDS34002.1 - 1.4 8.7 8.1 4.5 7.0 2.6 2.6 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 Mito_fiss_reg PF05308.11 CDS34002.1 - 2.5 8.1 7.3 0.72 9.9 2.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator zf-AN1 PF01428.16 CDS34002.1 - 7.2 6.9 15.6 6.2 7.1 1.6 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger MA3 PF02847.17 CDS34004.1 - 3.7e-28 97.8 0.4 6.1e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 MA3 domain SMC_N PF02463.19 CDS34006.2 - 1.3e-60 204.6 12.7 6.3e-60 202.3 12.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDS34006.2 - 4.4e-21 75.4 0.2 3.6e-13 49.8 0.0 3.2 3 0 0 3 3 3 2 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CDS34006.2 - 5.2e-17 62.6 3.9 2.2e-07 31.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDS34006.2 - 5.1e-12 46.7 14.0 5.1e-12 46.7 14.0 7.3 4 2 2 6 6 6 1 AAA domain AAA_29 PF13555.6 CDS34006.2 - 5.2e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CDS34006.2 - 2e-07 31.1 26.7 2e-07 31.1 26.7 4.7 2 2 2 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 CDS34006.2 - 0.019 15.2 0.0 0.068 13.4 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CDS34006.2 - 0.089 13.3 0.0 0.089 13.3 0.0 6.7 6 3 0 6 6 6 0 ABC transporter INSIG PF07281.12 CDS34007.1 - 1.9e-32 112.6 10.0 7.7e-31 107.4 10.0 2.2 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Dynactin_p22 PF07426.11 CDS34008.1 - 1.8e-31 109.3 6.5 2e-31 109.1 6.5 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 Sec5 PF15469.6 CDS34008.1 - 0.03 14.1 2.9 0.48 10.2 0.1 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec5 UPF0227 PF05728.12 CDS34008.1 - 0.059 13.3 0.4 0.12 12.3 0.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) P16-Arc PF04699.14 CDS34008.1 - 0.1 13.1 4.7 1.7 9.1 4.7 2.1 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) UPF0242 PF06785.11 CDS34008.1 - 0.11 12.6 5.2 0.14 12.3 5.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NDUFV3 PF15880.5 CDS34009.1 - 3.6e-11 42.9 1.5 7e-11 42.0 1.5 1.5 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial UQ_con PF00179.26 CDS34010.1 - 6.1e-30 103.7 0.1 7.4e-30 103.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L29e PF01779.17 CDS34011.1 - 8e-22 77.3 9.3 8e-22 77.3 9.3 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family Pkinase PF00069.25 CDS34014.1 - 1.5e-47 162.2 0.0 1.9e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34014.1 - 1.5e-21 76.9 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS34014.1 - 2.5e-05 24.3 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDS34014.1 - 0.0077 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CDS34014.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CDS34014.1 - 0.015 14.9 0.2 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase R3H-assoc PF13902.6 CDS34014.1 - 0.025 14.9 0.4 0.048 14.0 0.4 1.4 1 0 0 1 1 1 0 R3H-associated N-terminal domain Kdo PF06293.14 CDS34014.1 - 0.06 12.7 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 CDS34014.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC wnt PF00110.19 CDS34016.1 - 2.6e-79 267.0 2.8 3.2e-79 266.7 2.8 1.0 1 0 0 1 1 1 1 wnt family DUF2718 PF10918.8 CDS34017.1 - 0.0038 17.7 0.2 0.014 15.9 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2718) zf-C2H2 PF00096.26 CDS34019.1 - 2.4e-10 40.3 19.4 8.9e-06 25.9 4.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34019.1 - 3.7e-07 30.4 17.4 0.0024 18.5 2.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34019.1 - 0.0016 18.7 14.4 0.039 14.4 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDS34019.1 - 0.014 15.3 14.6 0.032 14.2 1.0 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.19 CDS34019.1 - 0.022 15.0 8.4 0.34 11.3 0.0 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-met PF12874.7 CDS34019.1 - 0.033 14.6 7.3 0.12 12.8 0.6 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BolA PF01722.18 CDS34019.1 - 0.19 12.0 1.7 0.51 10.6 0.9 2.0 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.8 CDS34019.1 - 0.76 10.1 6.6 3.8 7.9 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 CDS34019.1 - 1.3 9.2 4.7 0.52 10.4 1.5 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 CDS34019.1 - 4.3 7.1 8.0 0.28 10.9 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_ribbon_SprT PF17283.2 CDS34019.1 - 7.3 6.6 10.6 0.61 10.0 5.9 1.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 CDS34020.1 - 1.6e-11 44.0 19.6 5.4e-06 26.6 4.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34020.1 - 2.4e-06 27.9 17.4 0.0011 19.6 2.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34020.1 - 1.6e-05 25.1 14.4 0.00081 19.7 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDS34020.1 - 0.01 15.8 10.6 0.27 11.3 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CDS34020.1 - 0.055 13.9 12.4 0.12 12.8 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BolA PF01722.18 CDS34020.1 - 0.066 13.5 0.9 0.27 11.5 0.4 2.1 1 1 1 2 2 2 0 BolA-like protein zf-Di19 PF05605.12 CDS34020.1 - 0.072 13.4 11.5 1.6 9.1 0.7 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDS34020.1 - 0.11 12.8 12.2 6.9 7.1 0.1 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CDS34020.1 - 5.9 7.3 9.6 3 8.2 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 CDS34020.1 - 6.2 6.9 6.2 1.2 9.2 1.9 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HE PF16278.5 CDS34020.1 - 6.9 7.2 12.6 0.64 10.5 0.9 3.5 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-UBP PF02148.19 CDS34020.1 - 9 6.7 9.2 1.6e+02 2.7 9.2 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.26 CDS34021.1 - 2.3e-12 46.6 17.3 9e-06 25.9 4.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34021.1 - 7.7e-08 32.5 15.0 0.0024 18.5 2.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS34021.1 - 0.00017 21.5 9.4 0.0029 17.5 0.1 2.7 2 1 1 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34021.1 - 0.0008 19.7 16.1 0.011 16.1 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 CDS34021.1 - 0.0074 16.6 9.7 0.12 12.8 0.6 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CDS34021.1 - 0.008 16.5 5.5 0.46 10.8 2.3 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-Di19 PF05605.12 CDS34021.1 - 0.11 12.9 9.2 0.23 11.8 0.2 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-UBP PF02148.19 CDS34021.1 - 0.58 10.5 10.6 2.5 8.5 0.4 2.6 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Elf1 PF05129.13 CDS34021.1 - 0.84 9.7 4.4 0.67 10.1 1.4 2.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.8 CDS34021.1 - 1.1 9.7 4.2 3.8 7.9 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.7 CDS34021.1 - 1.8 8.8 5.0 21 5.4 1.8 2.9 2 0 0 2 2 2 0 Zinc-binding zf-C2H2 PF00096.26 CDS34022.1 - 1.2e-10 41.2 19.4 7.3e-06 26.2 4.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34022.1 - 2.2e-07 31.1 17.4 0.002 18.8 2.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34022.1 - 0.003 17.9 13.6 0.032 14.7 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDS34022.1 - 0.0089 16.0 14.8 0.027 14.5 1.1 3.3 2 1 1 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CDS34022.1 - 0.025 15.0 7.3 0.096 13.1 0.6 2.9 3 0 0 3 3 2 0 Zinc-finger of C2H2 type CopG_antitoxin PF12441.8 CDS34022.1 - 0.048 14.2 0.5 0.21 12.2 0.0 2.2 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system LcrV PF04792.12 CDS34022.1 - 0.062 12.6 0.2 5.5 6.2 0.0 2.4 2 0 0 2 2 2 0 V antigen (LcrV) protein BolA PF01722.18 CDS34022.1 - 0.12 12.6 1.6 0.42 10.9 0.9 2.1 1 1 1 2 2 2 0 BolA-like protein zf-UBP PF02148.19 CDS34022.1 - 0.16 12.4 9.7 1.3e+02 2.9 9.7 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-RRN7 PF11781.8 CDS34022.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_jaz PF12171.8 CDS34022.1 - 0.5 10.7 6.6 3.1 8.2 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CDS34022.1 - 0.97 9.9 12.8 0.29 11.6 1.3 3.2 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 CDS34022.1 - 1.4 9.3 12.9 2.6 8.4 1.1 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 CDS34022.1 - 2.1 8.4 7.4 9.3 6.4 7.4 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 CDS34022.1 - 6 6.9 11.8 0.49 10.4 5.9 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Trypsin PF00089.26 CDS34023.1 - 2.2e-13 50.5 0.0 3.5e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CDS34023.1 - 0.0018 19.2 0.0 0.0029 18.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CDS34023.1 - 0.15 12.4 0.0 2.3 8.6 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) BORA_N PF15280.6 CDS34024.1 - 2.4e-24 86.3 0.4 2.4e-24 86.3 0.4 2.3 3 0 0 3 3 3 1 Protein aurora borealis N-terminus DUF4706 PF15797.5 CDS34024.1 - 0.074 13.6 0.1 0.46 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) RPN1_RPN2_N PF17781.1 CDS34024.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Glycos_transf_2 PF00535.26 CDS34025.1 - 3.5e-16 59.5 0.1 7.8e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4495 PF14906.6 CDS34025.1 - 2.3e-08 33.5 0.1 3.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4495) Glyco_tranf_2_3 PF13641.6 CDS34025.1 - 3.7e-07 30.3 0.0 1.3e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CDS34025.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TauE PF01925.19 CDS34026.2 - 0.003 17.2 0.4 0.0036 17.0 0.4 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE CD225 PF04505.12 CDS34026.2 - 0.5 10.5 8.3 11 6.2 8.3 2.4 1 1 0 1 1 1 0 Interferon-induced transmembrane protein CAP_GLY PF01302.25 CDS34027.1 - 1.6e-50 169.0 5.6 1.5e-26 92.1 0.9 2.4 2 0 0 2 2 2 2 CAP-Gly domain CLIP1_ZNF PF16641.5 CDS34027.1 - 4.2e-14 52.0 16.3 3e-07 30.1 4.3 2.3 2 0 0 2 2 2 2 CLIP1 zinc knuckle CEP63 PF17045.5 CDS34027.1 - 5.7e-05 23.1 4.6 5.7e-05 23.1 4.6 5.9 2 2 3 5 5 5 1 Centrosomal protein of 63 kDa Tiam_CC_Ex PF18385.1 CDS34027.1 - 0.63 10.5 3.1 9.3 6.7 0.0 3.7 3 0 0 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain Vac_Fusion PF02346.16 CDS34027.1 - 1.2 8.8 8.5 18 5.0 2.1 4.8 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Pkinase PF00069.25 CDS34028.2 - 1.2e-99 333.0 0.0 3e-52 177.6 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34028.2 - 1.7e-52 178.3 0.0 1.7e-26 93.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDS34028.2 - 1.1e-08 34.7 0.0 0.0045 16.3 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CDS34028.2 - 0.0011 18.4 0.0 1.9 7.8 0.0 2.6 2 2 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDS34028.2 - 0.0064 16.4 0.1 5 7.0 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family FHA PF00498.26 CDS34028.2 - 0.02 15.2 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 FHA domain DUF5129 PF17173.4 CDS34028.2 - 0.072 12.2 0.1 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) Arm_2 PF04826.13 CDS34029.1 - 3e-07 30.1 7.2 9.9e-06 25.2 7.2 2.2 1 1 0 1 1 1 1 Armadillo-like DEAD PF00270.29 CDS34030.1 - 6.6e-43 146.5 0.0 1.3e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS34030.1 - 5.6e-27 94.3 0.1 2.6e-26 92.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDS34030.1 - 0.13 12.5 0.1 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MRP-S31 PF15433.6 CDS34030.1 - 0.54 9.9 5.7 0.89 9.2 5.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 ELMO_CED12 PF04727.13 CDS34032.2 - 1.5e-32 113.2 0.6 1.9e-32 112.8 0.2 1.3 1 1 0 1 1 1 1 ELMO/CED-12 family CwfJ_C_2 PF04676.14 CDS34033.2 - 9.8e-22 77.7 0.0 3.5e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CDS34033.2 - 6.5e-16 58.3 0.1 1.2e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF16 PF01519.16 CDS34033.2 - 0.048 14.2 0.3 0.048 14.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 CALM_bind PF16025.5 CDS34033.2 - 1.3 9.5 8.2 1.5 9.3 0.0 3.8 4 0 0 4 4 4 0 Calcium-dependent calmodulin binding Ets PF00178.22 CDS34036.2 - 1e-26 93.2 0.8 2.5e-26 91.9 0.8 1.7 1 0 0 1 1 1 1 Ets-domain SET PF00856.28 CDS34038.1 - 3.2e-21 76.4 0.6 2.5e-19 70.3 0.1 3.3 2 1 0 2 2 2 1 SET domain PWWP PF00855.17 CDS34038.1 - 1e-06 29.0 1.1 0.00044 20.6 0.2 3.3 2 1 0 2 2 2 2 PWWP domain AWS PF17907.1 CDS34038.1 - 5.2e-06 26.4 10.5 5.2e-06 26.4 10.5 2.8 2 0 0 2 2 2 1 AWS domain PHD PF00628.29 CDS34038.1 - 6.6e-06 25.9 11.3 6.6e-06 25.9 11.3 7.5 6 1 2 8 8 8 3 PHD-finger C5HCH PF17982.1 CDS34038.1 - 0.0004 20.5 4.4 0.0004 20.5 4.4 5.7 5 2 1 6 6 6 2 NSD Cys-His rich domain IR1-M PF12185.8 CDS34038.1 - 2 8.4 4.4 0.69 9.9 0.5 2.2 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DSS1_SEM1 PF05160.13 CDS34039.1 - 7.9e-20 70.7 6.0 9.7e-20 70.4 6.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family RRM_1 PF00076.22 CDS34040.1 - 0.00023 20.9 0.1 0.00047 19.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDS34040.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 BRAP2 PF07576.12 CDS34040.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Cyclin_C_2 PF16899.5 CDS34041.1 - 3.9e-14 52.9 0.0 4.9e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CDS34041.1 - 0.00014 21.6 0.1 0.00052 19.7 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain SET PF00856.28 CDS34042.1 - 3.3e-13 50.4 6.4 3.4e-13 50.3 0.1 3.3 2 2 0 2 2 2 1 SET domain DUF1690 PF07956.11 CDS34043.1 - 1.5e-05 25.4 9.2 8.8e-05 22.9 9.2 1.9 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF737 PF05300.11 CDS34043.1 - 0.0033 17.8 1.7 0.005 17.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.13 CDS34043.1 - 0.0097 16.0 0.8 0.017 15.2 0.8 1.5 1 0 0 1 1 1 1 CHCH domain DENN PF02141.21 CDS34044.1 - 1.2e-28 100.3 4.3 1.2e-27 97.0 2.2 3.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 CDS34044.1 - 0.00026 20.9 0.2 0.0019 18.2 0.1 2.5 2 0 0 2 2 2 1 dDENN domain Avl9 PF09794.9 CDS34044.1 - 0.16 10.6 0.2 0.26 9.9 0.2 1.2 1 0 0 1 1 1 0 Transport protein Avl9 CWC25 PF12542.8 CDS34045.1 - 2.1e-09 38.2 2.2 2.1e-09 38.2 2.2 4.4 3 1 0 3 3 3 1 Pre-mRNA splicing factor DUF755 PF05501.11 CDS34045.1 - 0.0085 16.4 15.2 0.0085 16.4 15.2 4.8 3 1 2 5 5 5 2 Domain of unknown function (DUF755) DUF572 PF04502.13 CDS34045.1 - 1.4 8.4 41.1 0.33 10.5 28.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Nop14 PF04147.12 CDS34046.2 - 0.18 10.0 31.3 0.22 9.7 31.3 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 CDS34046.2 - 0.26 10.1 28.3 0.3 9.9 28.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 CDS34046.2 - 0.37 10.2 34.2 0.44 9.9 34.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CDS34046.2 - 0.75 9.1 37.2 0.82 8.9 37.2 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 CDS34046.2 - 1 8.1 18.0 1.5 7.5 18.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2201_N PF13203.6 CDS34046.2 - 1.6 8.2 8.1 2.1 7.9 8.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Presenilin PF01080.17 CDS34046.2 - 2 7.1 20.8 2.9 6.6 20.8 1.4 1 0 0 1 1 1 0 Presenilin SURF2 PF05477.11 CDS34046.2 - 5.7 6.6 23.2 7.7 6.1 23.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LAP1C PF05609.12 CDS34046.2 - 10 5.1 24.7 11 5.0 24.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) eIF-5a PF01287.20 CDS34047.1 - 9.8e-10 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDS34047.1 - 2.4e-05 24.3 0.0 3.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Syntaxin PF00804.25 CDS34048.1 - 7.3e-39 133.5 10.9 2.1e-38 132.0 10.9 1.8 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CDS34048.1 - 1.9e-15 56.6 5.7 1.9e-15 56.6 5.7 3.3 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 CDS34048.1 - 8.4e-05 22.9 15.4 0.00014 22.2 5.9 3.3 2 1 1 3 3 3 1 Syntaxin-like protein DUF5345 PF17280.2 CDS34048.1 - 0.011 15.8 0.3 0.041 13.9 0.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5345) COG5 PF10392.9 CDS34048.1 - 0.078 13.2 6.7 1.6 8.9 0.0 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF4448 PF14610.6 CDS34048.1 - 0.084 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MCPsignal PF00015.21 CDS34048.1 - 0.087 12.6 4.0 3.5 7.4 2.0 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ETRAMP PF09716.10 CDS34048.1 - 0.096 12.8 1.6 0.17 11.9 1.6 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Microvir_H PF04687.12 CDS34048.1 - 0.11 11.9 1.8 0.16 11.3 0.5 1.7 1 1 1 2 2 2 0 Microvirus H protein (pilot protein) DUF772 PF05598.11 CDS34048.1 - 0.13 12.3 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Transposase domain (DUF772) Scm3 PF10384.9 CDS34048.1 - 0.16 11.7 2.0 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Centromere protein Scm3 EVI2A PF05399.11 CDS34048.1 - 0.28 10.7 3.8 0.65 9.6 3.8 1.7 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF2207 PF09972.9 CDS34048.1 - 0.29 9.8 4.7 0.42 9.3 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Herpes_US9 PF06072.11 CDS34048.1 - 0.66 9.9 2.5 0.91 9.4 1.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 TniQ PF06527.11 CDS34049.2 - 0.023 15.4 0.6 0.057 14.1 0.6 1.8 1 0 0 1 1 1 0 TniQ Ion_trans PF00520.31 CDS34050.1 - 1.3e-27 96.6 10.3 1.9e-27 96.1 10.3 1.3 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CDS34050.1 - 5.2e-27 94.0 0.5 1.8e-26 92.3 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Shal-type PF11601.8 CDS34050.1 - 3.6e-09 36.0 0.2 5.6e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels, N-terminal BTB_3 PF16017.5 CDS34050.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.16 CDS34050.1 - 0.024 14.6 3.3 0.024 14.6 3.3 2.2 2 0 0 2 2 2 0 Ion channel COX2-transmemb PF09125.10 CDS34050.1 - 0.091 12.6 1.1 0.26 11.1 1.1 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane PKD_channel PF08016.12 CDS34050.1 - 0.33 9.6 5.5 0.14 10.9 2.9 1.6 1 1 1 2 2 2 0 Polycystin cation channel SH2 PF00017.24 CDS34051.1 - 2e-09 37.4 0.0 3.1e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 CDS34051.1 - 0.00014 22.3 0.1 0.00041 20.8 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CDS34051.1 - 0.00062 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain LSM PF01423.22 CDS34052.1 - 7.7e-20 70.4 0.0 8.8e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDS34052.1 - 0.053 13.7 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain zf-C2H2 PF00096.26 CDS34053.2 - 1.6e-10 40.8 32.0 0.00055 20.2 3.7 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS34053.2 - 4.7e-08 33.1 5.1 1.2e-05 25.4 0.3 4.3 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS34053.2 - 7e-07 29.6 27.6 0.0029 18.3 2.9 4.3 4 0 0 4 4 3 3 C2H2-type zinc finger Rtf2 PF04641.12 CDS34053.2 - 9.3e-05 21.9 2.1 0.00017 21.0 2.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C2HC_2 PF13913.6 CDS34053.2 - 0.00011 22.0 1.8 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_aberr PF17017.5 CDS34053.2 - 0.0059 16.8 4.4 2.2 8.4 2.7 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger TRAF6_Z2 PF18048.1 CDS34053.2 - 0.017 15.2 1.6 0.017 15.2 1.6 3.5 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-Di19 PF05605.12 CDS34053.2 - 0.036 14.4 3.7 0.036 14.4 3.7 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 CDS34053.2 - 0.056 13.9 5.0 0.38 11.2 1.9 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 CDS34053.2 - 0.058 13.4 1.6 0.058 13.4 1.6 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDS34053.2 - 0.13 12.1 0.3 0.13 12.1 0.3 3.1 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 CDS34053.2 - 0.14 12.5 10.0 4.5 7.7 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CDS34053.2 - 0.24 12.1 16.2 3.3 8.4 0.4 4.0 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 CDS34053.2 - 2.2 8.8 8.7 14 6.3 0.7 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 CDS34053.2 - 8 7.3 9.1 3.2 8.6 3.3 2.6 1 1 2 3 3 3 0 zinc-ribbon family TTL PF03133.15 CDS34054.2 - 4.5e-68 229.5 0.2 7.9e-68 228.7 0.2 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family wnt PF00110.19 CDS34055.1 - 6.8e-101 337.9 3.3 1.3e-100 337.0 3.3 1.4 1 1 0 1 1 1 1 wnt family Peptidase_S49_N PF08496.10 CDS34056.1 - 0.0098 16.0 8.5 0.011 15.8 8.5 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal CSG2 PF16965.5 CDS34056.1 - 0.021 13.8 0.1 0.022 13.8 0.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SR-25 PF10500.9 CDS34056.1 - 0.023 14.3 20.0 0.025 14.2 20.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RICTOR_N PF14664.6 CDS34056.1 - 0.028 13.4 0.5 0.03 13.3 0.5 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Connexin PF00029.19 CDS34056.1 - 0.028 14.2 0.7 0.027 14.2 0.7 1.1 1 0 0 1 1 1 0 Connexin Cnd1_N PF12922.7 CDS34056.1 - 0.038 13.8 4.7 0.042 13.7 4.7 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Rxt3 PF08642.10 CDS34056.1 - 0.043 14.6 0.4 0.048 14.4 0.4 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 OATP PF03137.20 CDS34056.1 - 0.091 11.0 2.0 0.085 11.1 2.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.13 CDS34056.1 - 0.093 13.0 1.0 0.11 12.8 1.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Nucleoside_tran PF01733.18 CDS34056.1 - 0.095 12.1 1.2 0.11 11.9 1.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter Dala_Dala_lig_N PF01820.21 CDS34056.1 - 0.097 13.2 0.3 0.11 13.0 0.3 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus SHR3_chaperone PF08229.11 CDS34056.1 - 0.12 11.3 3.8 0.18 10.7 3.8 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Sugar_tr PF00083.24 CDS34056.1 - 0.18 10.6 1.5 0.21 10.4 1.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter FHIPEP PF00771.20 CDS34056.1 - 0.24 9.8 0.4 0.22 9.9 0.4 1.0 1 0 0 1 1 1 0 FHIPEP family Jak1_Phl PF17887.1 CDS34056.1 - 0.34 10.9 6.0 0.4 10.6 6.0 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain AP3D1 PF06375.11 CDS34056.1 - 0.51 10.6 17.5 0.6 10.3 17.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 BCIP PF13862.6 CDS34056.1 - 0.54 10.0 7.8 0.71 9.6 7.8 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DUF3464 PF11947.8 CDS34056.1 - 0.7 9.6 8.4 0.84 9.4 8.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Med19 PF10278.9 CDS34056.1 - 0.98 9.3 19.2 1.1 9.1 19.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TSP_1 PF00090.19 CDS34058.1 - 1.9e-05 24.8 7.5 1.9e-05 24.8 7.5 3.3 4 1 1 5 5 5 1 Thrombospondin type 1 domain EGF PF00008.27 CDS34058.1 - 0.018 15.3 41.3 0.05 13.9 2.3 5.8 5 1 0 5 5 5 0 EGF-like domain EGF_3 PF12947.7 CDS34058.1 - 0.024 14.9 1.9 0.024 14.9 1.9 4.8 4 1 0 4 4 4 0 EGF domain cEGF PF12662.7 CDS34058.1 - 0.094 12.7 20.9 1.2 9.2 0.7 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like MACPF PF01823.19 CDS34059.2 - 4e-16 59.7 0.0 7.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain cEGF PF12662.7 CDS34059.2 - 0.086 12.8 1.3 7.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Exo_endo_phos_2 PF14529.6 CDS34061.1 - 3.9e-11 42.8 0.2 1e-10 41.5 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS34061.1 - 0.00085 18.9 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PDZ_6 PF17820.1 CDS34062.1 - 8.9e-30 102.3 0.0 6.9e-10 38.6 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 CDS34062.1 - 9.1e-28 96.4 8.3 5.1e-10 39.6 0.1 5.0 3 1 2 5 5 5 4 PDZ domain PDZ_2 PF13180.6 CDS34062.1 - 1.3e-24 86.3 0.9 2.5e-09 37.3 0.0 4.5 3 2 2 5 5 5 3 PDZ domain GRASP55_65 PF04495.14 CDS34062.1 - 1.5e-06 28.6 0.1 0.034 14.5 0.0 2.5 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain DUF3394 PF11874.8 CDS34062.1 - 0.00014 21.6 0.1 0.43 10.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3394) PTP_N PF12453.8 CDS34062.1 - 0.31 10.8 0.9 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal MATH PF00917.26 CDS34064.1 - 2e-07 31.1 0.0 1e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 MATH domain zf-B_box PF00643.24 CDS34064.1 - 1.1e-06 28.7 8.0 1.1e-06 28.7 8.0 2.6 2 0 0 2 2 2 1 B-box zinc finger zf-RING_2 PF13639.6 CDS34064.1 - 0.00012 22.4 12.9 0.00012 22.4 12.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS34064.1 - 0.00089 19.1 12.0 0.00089 19.1 12.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS34064.1 - 0.0073 16.1 10.0 0.0073 16.1 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4689 PF15755.5 CDS34064.1 - 0.075 12.6 1.0 0.1 12.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4689) ZapB PF06005.12 CDS34064.1 - 0.1 13.0 0.2 0.1 13.0 0.2 3.5 3 1 0 3 3 3 0 Cell division protein ZapB zf-C3HC4 PF00097.25 CDS34064.1 - 0.58 10.1 29.9 0.023 14.6 12.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 CDS34064.1 - 4.6 6.9 14.4 5.2 6.7 4.6 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DLP_helical PF18709.1 CDS34064.1 - 6.9 5.8 7.8 0.37 10.0 2.0 1.8 2 0 0 2 2 2 0 Dynamin-like helical domain ATG16 PF08614.11 CDS34065.1 - 0.00088 19.5 12.8 0.00088 19.5 12.8 11.0 3 3 7 10 10 10 1 Autophagy protein 16 (ATG16) DUF743 PF05332.11 CDS34065.1 - 0.093 12.8 1.5 0.67 10.0 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF743) DUF5104 PF17117.5 CDS34065.1 - 0.36 11.3 3.9 0.87 10.1 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) YojJ PF10372.9 CDS34065.1 - 2 8.6 15.7 5.1 7.3 1.1 5.6 4 1 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus Phage_int_SAM_2 PF12834.7 CDS34065.1 - 4.3 8.1 7.6 8.4 7.2 0.6 4.0 3 0 0 3 3 3 0 Phage integrase, N-terminal IPP-2 PF04979.14 CDS34066.1 - 1.7e-33 116.2 3.5 2.9e-33 115.4 3.5 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF4735 PF15882.5 CDS34069.1 - 1.2e-75 254.7 0.0 1.4e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4735) Glyco_hydro_99 PF16317.5 CDS34069.1 - 0.005 16.0 0.0 0.0072 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 gag-asp_proteas PF13975.6 CDS34070.1 - 0.053 14.1 0.0 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS34070.1 - 0.059 14.0 0.0 0.14 12.8 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 CDS34071.1 - 1.1e-20 74.1 0.0 2.2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDS34071.1 - 6.2e-14 51.9 1.6 1.2e-13 51.0 1.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDS34071.1 - 0.17 12.1 0.0 1.3 9.2 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain Exo_endo_phos PF03372.23 CDS34072.1 - 4.6e-09 36.1 0.0 1e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HLH PF00010.26 CDS34073.1 - 6.9e-13 48.3 0.8 1.4e-12 47.4 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DHR10 PF18595.1 CDS34073.1 - 4.5 7.4 8.8 0.17 11.9 2.0 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Inositol_P PF00459.25 CDS34074.1 - 4.7e-71 239.5 0.1 5.6e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Tmemb_161AB PF10268.9 CDS34075.1 - 2e-158 527.9 10.5 2.3e-158 527.8 10.5 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB JmjC PF02373.22 CDS34076.2 - 6.7e-80 265.0 0.4 2.1e-38 131.2 0.0 2.7 2 0 0 2 2 2 2 JmjC domain, hydroxylase JmjN PF02375.17 CDS34076.2 - 6.6e-25 86.8 0.6 5.4e-11 42.3 0.1 2.7 2 0 0 2 2 2 2 jmjN domain zf-HC5HC2H_2 PF13832.6 CDS34076.2 - 2.4e-05 24.4 2.4 0.0054 16.9 1.9 4.0 3 1 0 3 3 3 2 PHD-zinc-finger like domain Tudor_2 PF18104.1 CDS34076.2 - 4e-05 23.2 0.1 0.047 13.4 0.1 3.2 3 0 0 3 3 3 2 Jumonji domain-containing protein 2A Tudor domain PHD_2 PF13831.6 CDS34076.2 - 0.00016 21.1 18.6 0.0057 16.2 14.7 3.9 2 1 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 CDS34076.2 - 0.00042 20.5 2.6 0.00042 20.5 2.6 3.6 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.29 CDS34076.2 - 0.00066 19.5 15.7 0.0017 18.2 6.3 3.3 2 0 0 2 2 2 1 PHD-finger DUF2147 PF09917.9 CDS34076.2 - 0.009 16.7 0.0 7.5 7.3 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2147) DUF4570 PF15134.6 CDS34076.2 - 0.18 11.8 0.2 30 4.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) WSK PF03832.13 CDS34076.2 - 9.5 6.0 8.0 40 4.0 8.0 2.2 1 0 0 1 1 1 0 WSK motif TAF4 PF05236.14 CDS34077.1 - 5.2e-20 72.3 6.7 7.7e-20 71.8 6.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.14 CDS34077.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 NHR1 homology to TAF HLH PF00010.26 CDS34078.1 - 2.6e-12 46.5 2.8 4.2e-12 45.8 2.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-CRD PF17979.1 CDS34079.1 - 1.4e-05 25.3 19.1 0.05 13.7 0.9 4.6 4 0 0 4 4 4 3 Cysteine rich domain with multizinc binding regions zf-C2H2_4 PF13894.6 CDS34079.1 - 0.0027 18.4 37.6 1.3 10.0 1.4 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDS34079.1 - 8 6.9 12.8 0.26 11.7 0.3 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) Bmp PF02608.14 CDS34080.1 - 0.012 14.6 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like DUF1554 PF07588.11 CDS34080.1 - 0.047 13.5 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) SAM_1 PF00536.30 CDS34081.1 - 2.1e-07 31.2 0.0 3.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS34081.1 - 5.4e-05 23.2 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CDS34081.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Endostatin PF06482.11 CDS34081.1 - 1.8 8.0 6.1 3.2 7.1 6.1 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin AT_hook PF02178.19 CDS34081.1 - 4.2 7.6 14.7 0.26 11.3 5.9 2.5 2 0 0 2 2 2 0 AT hook motif Presenilin PF01080.17 CDS34081.1 - 5.1 5.8 4.6 7.2 5.3 4.6 1.1 1 0 0 1 1 1 0 Presenilin COX15-CtaA PF02628.15 CDS34082.1 - 1.8e-93 313.1 8.7 2.1e-93 312.9 8.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein AMP-binding PF00501.28 CDS34083.1 - 1.3e-27 96.5 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.6 CDS34083.1 - 1.1e-23 84.1 0.0 2.7e-09 37.0 0.0 3.2 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 CDS34083.1 - 4.1e-15 55.7 0.2 0.011 16.2 0.0 6.9 7 0 0 7 7 7 4 PQQ-like domain PQQ PF01011.21 CDS34083.1 - 8e-12 44.5 0.2 0.00011 21.9 0.0 4.9 5 0 0 5 5 5 3 PQQ enzyme repeat DSPc PF00782.20 CDS34084.1 - 1.6e-11 44.2 0.0 2.1e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDS34084.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Headcase PF16002.5 CDS34084.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Headcase protein CDKN3 PF05706.12 CDS34084.1 - 0.035 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) ASH PF15780.5 CDS34084.1 - 0.044 14.0 0.0 2.7 8.3 0.0 2.5 2 1 1 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Y_phosphatase3 PF13350.6 CDS34084.1 - 0.17 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_16 PF10294.9 CDS34085.1 - 3.9e-12 46.3 0.1 9.5e-12 45.0 0.1 1.6 1 1 1 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CDS34085.1 - 3.8e-07 30.1 0.0 6.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDS34085.1 - 1.7e-06 27.9 0.0 4.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS34085.1 - 8.3e-06 25.4 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CDS34085.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CDS34085.1 - 0.00092 19.9 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDS34085.1 - 0.0028 17.1 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 CDS34085.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 CDS34085.1 - 0.079 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TBPIP PF07106.13 CDS34086.1 - 1.2e-20 73.2 0.0 2.5e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CDS34086.1 - 4.6e-15 55.5 0.2 1e-14 54.3 0.2 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FlxA PF14282.6 CDS34086.1 - 4.8e-05 23.3 3.0 8.2e-05 22.5 3.0 1.4 1 0 0 1 1 1 1 FlxA-like protein Tropomyosin_1 PF12718.7 CDS34086.1 - 0.00078 19.6 7.9 0.0011 19.1 7.6 1.4 1 1 0 1 1 1 1 Tropomyosin like ORF6C PF10552.9 CDS34086.1 - 0.0015 18.5 4.7 0.57 10.3 1.5 2.4 1 1 1 2 2 2 2 ORF6C domain NBP1 PF08537.10 CDS34086.1 - 0.003 17.0 2.0 0.004 16.6 2.0 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 HAP1_N PF04849.13 CDS34086.1 - 0.0033 16.7 3.3 0.0047 16.2 3.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Ran-binding PF05508.11 CDS34086.1 - 0.0058 15.6 2.2 0.0079 15.2 2.2 1.2 1 0 0 1 1 1 1 RanGTP-binding protein ATG16 PF08614.11 CDS34086.1 - 0.012 15.9 3.7 0.26 11.5 1.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SKA1 PF07160.12 CDS34086.1 - 0.013 15.4 3.8 0.018 14.9 3.8 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 CDS34086.1 - 0.022 14.9 2.1 0.022 14.9 2.1 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4795 PF16043.5 CDS34086.1 - 0.029 14.0 5.5 0.037 13.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 CDS34086.1 - 0.045 13.8 7.9 0.062 13.3 5.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 CDS34086.1 - 0.06 13.4 5.0 0.11 12.5 5.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FliD_C PF07195.12 CDS34086.1 - 0.1 12.0 2.6 5.6 6.3 0.0 2.2 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus LPP PF04728.13 CDS34086.1 - 0.11 12.9 4.2 0.38 11.2 3.9 2.2 2 1 0 2 2 1 0 Lipoprotein leucine-zipper Spc7 PF08317.11 CDS34086.1 - 0.11 11.3 8.8 0.38 9.6 8.6 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein GPS2_interact PF15784.5 CDS34086.1 - 0.15 12.5 5.2 2.8 8.5 0.8 2.4 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Uso1_p115_C PF04871.13 CDS34086.1 - 0.16 12.4 5.5 0.21 12.0 5.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 CDS34086.1 - 0.19 12.0 7.4 42 4.5 7.4 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 CDS34086.1 - 0.25 11.1 3.3 0.31 10.8 1.9 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 CDS34086.1 - 0.35 10.9 3.9 0.56 10.2 2.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 CDS34086.1 - 0.42 10.7 5.9 62 3.8 5.9 2.8 1 1 0 1 1 1 0 Swi5 KELK PF15796.5 CDS34086.1 - 1 9.8 7.6 3.6 8.1 4.4 2.4 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4200 PF13863.6 CDS34086.1 - 2.1 8.8 10.9 0.81 10.1 1.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Kinesin PF00225.23 CDS34087.1 - 1.2e-115 386.1 0.7 1.9e-115 385.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDS34087.1 - 3.7e-26 91.9 0.1 1.3e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding UPF0242 PF06785.11 CDS34087.1 - 0.0007 19.8 8.9 0.0007 19.8 8.9 3.3 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Kinesin_assoc PF16183.5 CDS34087.1 - 0.039 14.1 4.6 0.037 14.2 2.0 2.5 2 1 0 2 2 2 0 Kinesin-associated AAA_16 PF13191.6 CDS34087.1 - 0.08 13.3 0.7 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain TRAM_LAG1_CLN8 PF03798.16 CDS34088.1 - 3.5e-25 88.9 15.6 3.5e-25 88.9 15.6 2.8 3 0 0 3 3 3 1 TLC domain DUF2207 PF09972.9 CDS34088.1 - 6.9 5.3 6.2 1.2 7.8 0.3 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 CDS34089.1 - 1.6e-42 145.8 32.1 1.6e-42 145.8 32.1 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CDS34089.1 - 3.6e-33 114.9 32.9 3.6e-33 114.9 32.9 2.1 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 CDS34089.1 - 9.2e-20 70.5 10.8 9.2e-20 70.5 10.8 4.7 5 0 0 5 5 5 1 C-terminus of AA_permease Endosulfine PF04667.17 CDS34090.1 - 2.9e-08 33.7 0.7 4.9e-08 33.0 0.4 1.7 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Usp PF00582.26 CDS34091.1 - 4.9e-26 91.9 0.0 7.4e-26 91.3 0.0 1.3 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS34092.1 - 1.8e-12 48.0 0.0 2.4e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS34093.1 - 3.1e-20 73.1 0.0 4.2e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS34094.1 - 2.4e-10 41.1 0.0 3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS34095.1 - 2e-21 77.0 0.0 2.5e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 CDS34096.1 - 7.4e-26 91.3 0.0 1e-25 90.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family CTC1 PF15489.6 CDS34097.1 - 0.18 9.3 0.0 0.23 9.0 0.0 1.0 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Usp PF00582.26 CDS34098.1 - 5.1e-25 88.6 0.0 9.7e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family Ndr PF03096.14 CDS34099.2 - 2.6e-31 108.4 0.0 5.4e-31 107.4 0.0 1.4 1 1 0 1 1 1 1 Ndr family FtsJ PF01728.19 CDS34100.1 - 2.8e-39 135.1 0.0 3.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CDS34100.1 - 0.018 14.9 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Fibrillin_U_N PF18193.1 CDS34100.1 - 0.089 12.9 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Methyltr_RsmB-F PF01189.17 CDS34100.1 - 0.18 11.4 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F YdjM PF04307.14 CDS34101.1 - 3.4e-05 23.2 5.1 3.4e-05 23.2 5.1 1.7 2 0 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase Amastin PF07344.11 CDS34101.1 - 9.5 6.0 8.8 14 5.5 2.1 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein ATP_bind_1 PF03029.17 CDS34102.1 - 5.2e-74 249.1 0.0 6e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CDS34102.1 - 0.0056 17.0 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CDS34102.1 - 0.0077 16.8 0.0 0.029 14.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CDS34102.1 - 0.049 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDS34102.1 - 0.055 13.8 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CDS34102.1 - 0.058 13.1 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDS34102.1 - 0.064 13.6 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CDS34102.1 - 0.071 13.5 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CDS34102.1 - 0.087 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDS34102.1 - 0.095 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CDS34102.1 - 0.1 13.1 0.0 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 CDS34102.1 - 0.19 11.3 0.0 0.94 9.0 0.0 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region NICE-3 PF07406.11 CDS34103.1 - 3.6e-16 59.7 2.2 1.6e-14 54.3 2.2 2.3 1 1 0 1 1 1 1 NICE-3 protein Mig-14 PF07395.11 CDS34103.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Mig-14 MFS_1 PF07690.16 CDS34104.1 - 9.7e-23 80.6 16.8 9.7e-23 80.6 16.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Spt5-NGN PF03439.13 CDS34105.1 - 9.1e-23 80.0 0.0 2.1e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CDS34105.1 - 2.2e-18 65.5 0.1 0.0056 16.6 0.0 5.5 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.8 CDS34105.1 - 2.3e-08 34.9 12.3 2.3e-08 34.9 12.3 2.5 1 1 1 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal API5 PF05918.11 CDS34106.1 - 2.7e-82 277.3 0.2 3.1e-82 277.1 0.2 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) IFN-gamma PF00714.17 CDS34106.1 - 0.034 14.0 0.2 0.034 14.0 0.2 1.9 2 0 0 2 2 2 0 Interferon gamma PhoU_div PF01865.16 CDS34106.1 - 0.07 12.5 0.4 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF47 CNOT11 PF10155.9 CDS34106.1 - 0.12 12.6 2.0 2.3 8.4 0.5 2.9 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 Catalase_C PF18011.1 CDS34106.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain found in long catalases HEAT_2 PF13646.6 CDS34106.1 - 0.16 12.3 0.0 0.68 10.4 0.0 2.0 2 0 0 2 2 2 0 HEAT repeats zf-C2H2_aberr PF17017.5 CDS34107.1 - 0.041 14.0 1.0 0.075 13.2 1.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger dCMP_cyt_deam_1 PF00383.23 CDS34108.1 - 7.2e-18 64.3 1.1 9.7e-18 63.9 1.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDS34108.1 - 3.2e-16 59.4 0.0 3.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 CDS34108.1 - 0.0002 21.2 0.2 0.0003 20.6 0.2 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 CDS34108.1 - 0.003 17.7 0.1 0.0043 17.2 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 CDS34108.1 - 0.0042 17.1 1.2 0.011 15.8 1.2 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 CDS34108.1 - 0.028 14.5 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 CDS34108.1 - 0.032 14.3 0.2 0.046 13.8 0.2 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 CDS34108.1 - 0.037 14.2 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC3 E7 PF00527.18 CDS34108.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 E7 protein, Early protein zf-RING_2 PF13639.6 CDS34109.1 - 1.7e-14 53.8 8.0 1.7e-14 53.8 8.0 2.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS34109.1 - 7.4e-10 38.5 8.2 7.4e-10 38.5 8.2 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDS34109.1 - 7.4e-09 35.2 5.0 7.4e-09 35.2 5.0 3.0 3 0 0 3 3 3 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 CDS34109.1 - 1.2e-08 35.1 3.5 6e-08 32.8 1.2 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4_3 PF13920.6 CDS34109.1 - 3e-08 33.4 4.0 3e-08 33.4 4.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS34109.1 - 4.7e-08 32.8 8.3 4.7e-08 32.8 8.3 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS34109.1 - 6e-08 32.6 2.7 6e-08 32.6 2.7 3.0 3 1 1 4 4 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDS34109.1 - 1.8e-07 31.4 9.0 1.8e-07 31.4 9.0 2.6 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CDS34109.1 - 2.4e-07 30.6 6.7 2.4e-07 30.6 6.7 2.4 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS34109.1 - 3.7e-05 23.5 4.4 3.7e-05 23.5 4.4 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDS34109.1 - 0.0011 18.9 4.3 0.0011 18.9 4.3 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CDS34109.1 - 0.0052 16.9 5.2 0.0052 16.9 5.2 2.2 2 1 0 2 2 2 1 RING-variant domain zf-RING_4 PF14570.6 CDS34109.1 - 0.016 14.9 4.2 0.016 14.9 4.2 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CDS34109.1 - 0.16 11.9 14.0 0.9 9.5 0.8 2.9 2 1 1 3 3 3 0 PHD-finger FANCL_C PF11793.8 CDS34109.1 - 0.25 11.5 14.2 0.5 10.6 8.6 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_9 PF13901.6 CDS34109.1 - 0.27 11.2 8.4 9.3 6.2 0.1 3.0 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon zf-C3HC4_4 PF15227.6 CDS34109.1 - 2.3 8.4 12.5 1.1 9.5 5.1 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CDS34109.1 - 3.5 7.3 14.8 0.044 13.4 4.9 2.3 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 CDS34109.1 - 3.8 7.7 8.8 7 6.9 3.4 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-P11 PF03854.14 CDS34109.1 - 7.3 6.3 11.7 1 9.0 1.3 3.0 2 1 0 3 3 3 0 P-11 zinc finger LIM PF00412.22 CDS34110.1 - 1.8e-09 37.6 4.1 3.8e-09 36.6 4.1 1.6 1 0 0 1 1 1 1 LIM domain PDZ PF00595.24 CDS34110.1 - 0.00016 22.0 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CDS34110.1 - 0.00066 19.5 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 PDZ domain FAM76 PF16046.5 CDS34110.1 - 0.0021 17.5 5.1 0.0021 17.5 5.1 3.1 3 0 0 3 3 3 1 FAM76 protein Vps39_2 PF10367.9 CDS34110.1 - 0.077 13.4 1.3 0.67 10.4 0.3 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 PDZ_2 PF13180.6 CDS34110.1 - 0.12 12.7 0.1 0.44 10.9 0.1 1.9 1 1 0 1 1 1 0 PDZ domain MRP-S32 PF10210.9 CDS34111.1 - 4e-10 40.1 0.0 4.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Pertussis_S2S3 PF02918.15 CDS34111.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain PI3_PI4_kinase PF00454.27 CDS34112.1 - 2e-68 230.9 0.1 3.5e-68 230.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CDS34112.1 - 3.3e-65 220.6 1.7 5.8e-52 177.0 0.5 2.6 2 0 0 2 2 2 2 FAT domain DUF3385 PF11865.8 CDS34112.1 - 7.1e-36 123.6 4.8 1.5e-34 119.2 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CDS34112.1 - 1.3e-31 108.9 3.9 1.4e-31 108.8 0.2 3.1 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 CDS34112.1 - 3.5e-15 55.5 1.1 1.3e-14 53.6 0.3 2.3 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.6 CDS34112.1 - 0.00011 22.6 2.2 8.4 7.0 0.0 6.1 5 0 0 5 5 4 1 HEAT-like repeat NUC173 PF08161.12 CDS34112.1 - 0.00031 20.5 0.1 0.0017 18.1 0.1 2.3 1 0 0 1 1 1 1 NUC173 domain HEAT PF02985.22 CDS34112.1 - 0.0093 16.1 8.4 17 6.0 0.0 6.4 5 0 0 5 5 5 0 HEAT repeat Nod1 PF17114.5 CDS34112.1 - 0.079 13.1 0.3 1.5 9.0 0.1 3.2 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 PPDK_N PF01326.19 CDS34112.1 - 0.1 11.9 1.0 0.22 10.8 0.2 1.8 1 1 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CLASP_N PF12348.8 CDS34112.1 - 0.37 10.3 3.9 18 4.8 0.0 4.9 6 0 0 6 6 6 0 CLASP N terminal Tropomyosin PF00261.20 CDS34113.1 - 1.6e-11 44.0 38.0 2.2e-11 43.6 38.0 1.1 1 0 0 1 1 1 1 Tropomyosin DUF4164 PF13747.6 CDS34113.1 - 0.0099 16.1 8.0 0.0099 16.1 8.0 3.8 2 2 1 3 3 3 1 Domain of unknown function (DUF4164) Myosin_tail_1 PF01576.19 CDS34113.1 - 0.012 13.5 35.0 0.019 12.8 35.0 1.2 1 0 0 1 1 1 0 Myosin tail PelD_GGDEF PF16963.5 CDS34113.1 - 0.013 15.3 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 PelD GGDEF domain Filament PF00038.21 CDS34113.1 - 0.013 15.1 3.3 0.013 15.1 3.3 3.0 1 1 2 3 3 3 0 Intermediate filament protein GldM_N PF12081.8 CDS34113.1 - 0.015 15.4 3.3 0.015 15.4 3.3 3.4 1 1 1 2 2 2 0 GldM N-terminal domain SlyX PF04102.12 CDS34113.1 - 0.078 13.6 0.2 0.078 13.6 0.2 5.1 3 1 2 5 5 5 0 SlyX LPP PF04728.13 CDS34113.1 - 0.11 12.9 1.3 0.11 12.9 1.3 4.4 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 CDS34113.1 - 0.52 10.5 41.6 0.2 11.8 28.6 2.7 1 1 0 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 CDS34113.1 - 0.77 10.3 19.0 2 8.9 0.4 4.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 CDS34113.1 - 1.5 8.9 25.5 1 9.4 5.0 3.7 1 1 2 3 3 3 0 Laminin Domain II KASH_CCD PF14662.6 CDS34113.1 - 1.5 8.6 36.7 0.94 9.3 23.2 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 CDS34113.1 - 1.9 8.7 28.9 2.1 8.5 3.0 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CDS34113.1 - 2.7 8.4 22.9 0.17 12.3 1.0 5.0 2 2 5 7 7 7 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 CDS34113.1 - 3.7 7.6 35.9 0.39 10.8 4.5 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CDS34113.1 - 3.8 7.6 23.9 0.37 10.8 3.7 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 CDS34113.1 - 4.2 6.1 37.5 0.87 8.4 4.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 CDS34113.1 - 5.1 4.5 30.6 7.7 3.9 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 CDS34113.1 - 5.4 5.4 6.0 1.5 7.3 1.8 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family SHE3 PF17078.5 CDS34113.1 - 8.3 6.1 32.8 16 5.1 20.2 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 CDS34113.1 - 8.5 5.6 26.0 5.9e+02 -0.4 23.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TACC_C PF05010.14 CDS34113.1 - 9.7 5.9 35.1 0.18 11.6 13.2 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Pro_dh PF01619.18 CDS34114.1 - 3.8e-78 263.0 0.2 1.5e-77 261.1 0.2 2.0 2 1 0 2 2 2 1 Proline dehydrogenase NIL PF09383.10 CDS34114.1 - 0.021 14.6 0.0 8.3 6.3 0.0 3.0 3 0 0 3 3 3 0 NIL domain PPR_3 PF13812.6 CDS34114.1 - 0.036 14.2 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Glyco_hydro_97 PF10566.9 CDS34114.1 - 0.12 11.7 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Glycoside hydrolase 97 GRIP PF01465.20 CDS34116.1 - 7.1e-10 38.6 0.2 2.1e-09 37.1 0.2 1.9 1 0 0 1 1 1 1 GRIP domain TFA2_Winged_2 PF18121.1 CDS34116.1 - 0.021 14.5 1.4 0.071 12.8 0.1 2.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Prosystemin PF07376.11 CDS34116.1 - 0.1 12.1 2.4 0.21 11.0 2.4 1.4 1 0 0 1 1 1 0 Prosystemin CUTL PF16557.5 CDS34116.1 - 0.64 10.2 2.6 38 4.5 0.0 3.4 3 0 0 3 3 3 0 CUT1-like DNA-binding domain of SATB ADK PF00406.22 CDS34116.1 - 1.2 9.2 4.1 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Adenylate kinase Ig_3 PF13927.6 CDS34117.2 - 3.2e-51 171.8 3.9 2.4e-13 50.5 0.0 7.9 7 0 0 7 7 7 6 Immunoglobulin domain I-set PF07679.16 CDS34117.2 - 7.7e-40 134.9 0.0 7.3e-13 48.4 0.0 8.1 8 1 0 8 8 8 4 Immunoglobulin I-set domain Ig_2 PF13895.6 CDS34117.2 - 1.2e-34 118.5 2.6 7.8e-08 32.5 0.0 8.4 7 1 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 CDS34117.2 - 2.9e-26 91.4 3.6 6.4e-06 26.2 0.0 8.0 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 CDS34117.2 - 3.3e-24 85.2 2.1 1.7e-05 25.0 0.1 9.0 7 2 0 7 7 7 3 Immunoglobulin V-set domain fn3 PF00041.21 CDS34117.2 - 9.2e-20 70.8 0.1 8.5e-06 26.0 0.0 7.4 7 0 0 7 7 7 4 Fibronectin type III domain C2-set_2 PF08205.12 CDS34117.2 - 8.4e-09 35.4 2.6 0.018 15.1 0.1 5.7 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CDS34117.2 - 0.00036 20.5 0.0 1.1 9.4 0.0 3.4 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Ig_6 PF18452.1 CDS34117.2 - 0.0014 18.2 0.0 2.5 7.7 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin domain C1-set PF07654.15 CDS34117.2 - 0.0031 17.8 0.0 13 6.3 0.0 4.8 4 0 0 4 4 4 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 CDS34117.2 - 0.033 14.2 0.0 17 5.6 0.0 3.9 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Gyro_capsid PF04162.12 CDS34117.2 - 0.044 12.3 0.4 2.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Gyrovirus capsid protein (VP1) C2-set PF05790.15 CDS34117.2 - 0.079 13.2 0.0 26 5.1 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain CDC45 PF02724.14 CDS34118.1 - 1.6e-90 304.2 14.0 7.5e-70 236.0 10.5 3.0 1 1 1 2 2 2 2 CDC45-like protein YcbB PF08664.10 CDS34118.1 - 0.16 12.0 1.8 0.4 10.7 1.8 1.6 1 0 0 1 1 1 0 YcbB domain F-box PF00646.33 CDS34119.1 - 0.00012 21.8 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDS34119.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like SoxD PF04267.12 CDS34120.1 - 1.6 8.9 4.8 1.1 9.4 1.6 2.1 1 1 1 2 2 2 0 Sarcosine oxidase, delta subunit family CH PF00307.31 CDS34122.1 - 2e-65 217.8 0.4 1e-18 67.5 0.1 4.6 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS34122.1 - 8.3e-08 32.0 0.0 4.9e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CDS34122.1 - 0.015 15.4 0.1 2 8.6 0.0 3.3 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF3269 PF11673.8 CDS34122.1 - 0.051 13.9 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Allexi_40kDa PF05549.11 CDS34122.1 - 0.077 12.5 0.1 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein CH PF00307.31 CDS34123.1 - 2.6e-68 227.1 0.6 3.2e-19 69.1 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDS34123.1 - 4.9e-09 35.9 0.3 0.0034 17.2 0.0 3.7 3 0 0 3 3 3 3 CAMSAP CH domain CH_2 PF06294.11 CDS34123.1 - 0.038 14.1 0.0 8.2 6.6 0.0 3.5 4 0 0 4 4 4 0 CH-like domain in sperm protein zf-C2H2_9 PF16293.5 CDS34127.1 - 0.0019 18.0 1.9 0.0021 17.9 0.5 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 CDS34127.1 - 0.0092 16.3 5.2 0.02 15.2 1.9 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDS34127.1 - 0.11 12.9 0.2 0.11 12.9 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDS34127.1 - 0.69 10.9 12.5 2 9.5 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 CDS34127.1 - 1.6 9.3 6.8 10 6.7 0.1 3.9 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 CDS34127.1 - 2.9 8.5 12.3 2.1 9.0 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zinc_ribbon_16 PF17034.5 CDS34128.1 - 2.5e-08 34.2 13.0 3.1e-05 24.2 0.2 3.9 3 0 0 3 3 3 2 Zinc-ribbon like family PRIMA1 PF16101.5 CDS34128.1 - 0.57 10.2 13.1 1.7 8.7 1.7 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PPP1R35_C PF15503.6 CDS34130.1 - 6.7e-16 58.4 1.0 1e-15 57.8 1.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Prefoldin PF02996.17 CDS34131.1 - 1.3e-14 54.1 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit Forkhead PF00250.18 CDS34133.1 - 1.4e-38 131.0 0.4 2.2e-38 130.4 0.1 1.5 2 0 0 2 2 2 1 Forkhead domain RRM_1 PF00076.22 CDS34137.1 - 3.3e-12 46.1 0.0 5.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CDS34137.1 - 3.5e-06 26.9 1.7 3.5e-06 26.9 1.7 2.0 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 CDS34137.1 - 1.8e-05 25.4 0.0 4.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 CDS34137.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CDS34137.1 - 0.0022 18.0 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_4 PF18044.1 CDS34137.1 - 0.0031 17.3 2.2 0.007 16.1 2.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger RRM_7 PF16367.5 CDS34137.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif zf-CCCH PF00642.24 CDS34137.1 - 0.0074 16.2 2.4 0.0074 16.2 2.4 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDS34137.1 - 0.01 16.1 0.8 0.03 14.5 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDS34137.1 - 0.015 15.7 0.4 0.015 15.7 0.4 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FYVE PF01363.21 CDS34137.1 - 0.17 12.0 6.2 0.059 13.5 3.1 1.9 2 0 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 CDS34137.1 - 1.6 8.8 7.7 4.1 7.4 7.7 1.7 1 0 0 1 1 1 0 zinc-ribbons NB-ARC PF00931.22 CDS34140.1 - 0.018 14.3 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CDS34140.1 - 0.024 15.0 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CDS34140.1 - 0.025 14.9 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 CDS34140.1 - 0.026 14.6 0.0 0.079 13.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CDS34140.1 - 0.14 12.5 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDS34140.1 - 0.17 12.4 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter IPK PF03770.16 CDS34140.1 - 0.2 11.5 1.4 0.94 9.3 1.4 2.1 1 1 0 1 1 1 0 Inositol polyphosphate kinase Rep-A_N PF04057.12 CDS34142.2 - 0.15 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain PWWP PF00855.17 CDS34145.1 - 7.4e-18 64.7 0.4 2.7e-10 40.5 0.0 3.0 2 0 0 2 2 2 2 PWWP domain SET PF00856.28 CDS34145.1 - 1.4e-14 54.8 0.0 1.2e-13 51.8 0.0 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 CDS34145.1 - 6.4e-09 35.6 65.0 0.00062 19.6 3.0 6.9 4 2 1 5 5 5 4 PHD-finger C5HCH PF17982.1 CDS34145.1 - 6.2e-06 26.3 5.2 6.2e-06 26.3 5.2 3.5 2 0 0 2 2 2 1 NSD Cys-His rich domain zf-HIT PF04438.16 CDS34145.1 - 0.0062 16.4 5.8 0.0062 16.4 5.8 6.6 4 1 1 5 5 5 2 HIT zinc finger MOZ_SAS PF01853.18 CDS34146.1 - 3.4e-78 261.4 0.2 7.3e-78 260.3 0.2 1.6 1 0 0 1 1 1 1 MOZ/SAS family MIF4G PF02854.19 CDS34146.1 - 9.6e-45 152.8 6.4 3e-22 79.3 0.1 3.5 3 0 0 3 3 3 3 MIF4G domain zf-MYST PF17772.1 CDS34146.1 - 4.4e-20 71.1 4.9 4.4e-20 71.1 4.9 2.7 3 0 0 3 3 3 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDS34146.1 - 2.8e-16 59.1 0.5 1e-15 57.4 0.5 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Upf2 PF04050.14 CDS34146.1 - 3.2e-06 27.9 0.0 3.2e-06 27.9 0.0 3.6 3 1 0 3 3 3 1 Up-frameshift suppressor 2 EGF PF00008.27 CDS34146.1 - 3.1e-05 24.2 3.1 3.1e-05 24.2 3.1 4.5 3 1 0 3 3 3 1 EGF-like domain hEGF PF12661.7 CDS34146.1 - 0.0045 17.6 2.3 0.0045 17.6 2.3 5.4 5 0 0 5 5 5 2 Human growth factor-like EGF TFIIB PF00382.19 CDS34147.1 - 1.8e-42 143.2 5.6 4e-24 84.5 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CDS34147.1 - 3.7e-07 29.5 2.2 2.9e-06 26.7 0.1 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 CDS34147.1 - 1.4e-06 28.1 0.5 0.0006 19.6 0.0 2.1 1 1 1 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 CDS34147.1 - 0.0012 18.9 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Mito_carr PF00153.27 CDS34148.1 - 1.6e-65 217.1 0.8 1.5e-21 76.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp_protease PF09668.10 CDS34149.1 - 1.4e-51 173.5 0.3 2.1e-51 172.9 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDS34149.1 - 4e-18 65.7 0.0 7.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS34149.1 - 8.4e-08 32.8 0.0 1.5e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CDS34149.1 - 2.6e-05 24.5 0.0 5.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 CDS34149.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 CDS34149.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Rad60-SLD PF11976.8 CDS34149.1 - 0.067 13.0 0.2 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like RT_RNaseH_2 PF17919.1 CDS34150.1 - 7.1e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS34150.1 - 0.0071 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1935 PF09149.10 CDS34151.1 - 0.026 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) HTH_48 PF17906.1 CDS34152.1 - 3e-12 46.5 0.3 6.4e-12 45.4 0.3 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Homeobox_KN PF05920.11 CDS34153.1 - 2.1e-16 59.5 0.9 4.2e-16 58.6 0.5 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CDS34153.1 - 2.5e-08 33.6 1.5 5.2e-08 32.6 1.5 1.6 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 CDS34153.1 - 0.19 12.3 3.1 0.12 13.0 1.3 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 IZUMO PF15005.6 CDS34153.1 - 0.21 12.1 0.2 0.44 11.1 0.2 1.6 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated PTCB-BRCT PF12738.7 CDS34156.2 - 3.9e-45 151.6 5.6 1.2e-16 60.4 0.4 7.2 7 1 0 7 7 7 6 twin BRCT domain BRCT PF00533.26 CDS34156.2 - 1.3e-41 140.8 0.0 2.5e-09 37.4 0.1 7.4 7 1 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDS34156.2 - 4.4e-29 100.7 0.0 0.00019 21.8 0.0 7.8 8 0 0 8 8 8 7 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CDS34156.2 - 5.4e-13 49.0 0.0 0.016 15.5 0.0 7.0 7 1 0 7 7 7 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 CDS34156.2 - 4.7e-10 39.2 0.0 0.00054 19.8 0.0 5.7 6 0 0 6 6 6 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 CDS34156.2 - 0.00017 21.6 0.1 3.9 7.6 0.0 4.8 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Sec7 PF01369.20 CDS34157.1 - 7.4e-52 175.7 0.6 1.6e-51 174.6 0.3 1.7 2 0 0 2 2 2 1 Sec7 domain IQ_SEC7_PH PF16453.5 CDS34157.1 - 1.6e-45 154.5 0.2 3.7e-45 153.3 0.2 1.7 1 0 0 1 1 1 1 PH domain Snf7 PF03357.21 CDS34158.1 - 2.6e-37 128.1 20.7 3.3e-37 127.7 20.7 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CDS34158.1 - 5.6e-06 26.4 11.4 7.3e-06 26.0 11.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Sec39 PF08314.11 CDS34158.1 - 0.0046 15.5 8.3 0.0058 15.2 8.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 HAP1_N PF04849.13 CDS34158.1 - 0.12 11.6 16.7 0.25 10.5 16.1 1.6 1 1 1 2 2 2 0 HAP1 N-terminal conserved region PAXX PF15384.6 CDS34158.1 - 0.17 11.6 2.4 0.3 10.8 2.2 1.5 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DSBA PF01323.20 CDS34158.1 - 1.3 8.8 6.8 11 5.8 6.8 2.1 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Prefoldin_2 PF01920.20 CDS34158.1 - 3.8 7.5 19.6 0.53 10.3 5.4 2.5 3 0 0 3 3 3 0 Prefoldin subunit FYRN PF05964.14 CDS34159.1 - 2.1e-21 75.5 0.5 6e-21 74.0 0.5 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CDS34159.1 - 3.6e-20 71.9 0.0 8.8e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus SET PF00856.28 CDS34159.1 - 7.7e-19 68.7 0.4 7.7e-19 68.7 0.4 3.2 2 2 0 2 2 2 1 SET domain zf-HC5HC2H PF13771.6 CDS34159.1 - 5.1e-06 26.6 8.0 5.1e-06 26.6 8.0 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDS34159.1 - 4.4e-05 23.6 11.7 0.00016 21.8 11.7 2.0 1 0 0 1 1 1 1 PHD-zinc-finger like domain RRM_1 PF00076.22 CDS34160.1 - 2.1e-13 49.9 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS34160.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 CDS34162.1 - 8.9e-69 231.8 0.0 1.3e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34162.1 - 6e-31 107.7 0.0 9.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDS34162.1 - 2.8e-07 30.1 0.5 4.1e-07 29.6 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDS34162.1 - 7.9e-05 22.1 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kunitz_BPTI PF00014.23 CDS34164.1 - 3.8e-20 71.8 3.5 3.8e-20 71.8 3.5 1.5 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain HSM3_N PF18795.1 CDS34167.1 - 0.064 12.7 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, N terminal domain HEAT PF02985.22 CDS34168.2 - 2.6e-06 27.2 0.0 1 9.8 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 CDS34168.2 - 0.0015 18.8 2.2 11 6.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats Arm PF00514.23 CDS34168.2 - 0.0027 17.7 1.2 1.8 8.8 0.0 3.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDS34168.2 - 0.006 17.1 1.0 8.9 6.9 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Na_H_Exchanger PF00999.21 CDS34169.2 - 2.8e-61 207.4 45.2 3.5e-61 207.1 45.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RRM_1 PF00076.22 CDS34171.1 - 1.2e-25 89.1 0.2 2.4e-13 49.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS34171.1 - 2.6e-05 23.8 0.1 0.0059 16.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS34171.1 - 0.076 12.9 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif K_channel_TID PF07941.11 CDS34171.1 - 4 8.0 8.8 0.51 10.8 4.8 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RRM_1 PF00076.22 CDS34172.1 - 7.4e-22 77.0 0.1 2.7e-11 43.1 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS34172.1 - 4.5e-07 29.5 0.0 0.03 13.9 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS34172.1 - 0.00025 20.8 0.0 0.0072 16.2 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4523 PF15023.6 CDS34172.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 CDS34172.1 - 0.17 12.1 0.1 35 4.6 0.0 2.8 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SOCS_box PF07525.16 CDS34173.1 - 0.0011 19.3 0.6 0.0037 17.6 0.3 2.2 2 0 0 2 2 2 1 SOCS box ENTH PF01417.20 CDS34174.2 - 3e-18 66.1 0.8 6.7e-18 64.9 0.1 1.9 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 CDS34174.2 - 0.021 13.8 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 ANTH domain Musclin PF11037.8 CDS34174.2 - 0.27 11.2 8.5 3 7.8 0.3 3.2 3 0 0 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle LRR_8 PF13855.6 CDS34175.2 - 2.7e-52 174.4 45.8 9.4e-13 47.7 1.5 7.7 5 3 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 CDS34175.2 - 7.4e-37 124.8 63.1 0.00015 22.1 1.3 10.9 4 3 6 12 12 12 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDS34175.2 - 1.5e-12 47.4 19.7 2.9e-06 26.9 0.5 5.0 3 1 1 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 CDS34175.2 - 1.1e-09 37.6 39.7 0.22 11.6 0.0 14.0 14 0 0 14 14 14 5 Leucine Rich repeat LRR_1 PF00560.33 CDS34175.2 - 2.1e-06 27.5 52.0 12 6.9 0.3 15.9 14 3 0 14 14 14 2 Leucine Rich Repeat LRR_3 PF07725.12 CDS34175.2 - 0.14 12.0 5.1 0.44 10.5 0.3 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat RNase_PH PF01138.21 CDS34176.2 - 3.9e-05 24.1 0.2 0.001 19.6 0.0 2.1 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 LSM14 PF12701.7 CDS34177.2 - 4.9e-08 33.0 0.1 1.1e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDS34177.2 - 0.0011 19.8 0.0 0.0042 17.9 0.0 2.1 1 1 0 1 1 1 1 FDF domain DUF3090 PF11290.8 CDS34177.2 - 0.094 12.5 0.1 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Sterol-sensing PF12349.8 CDS34178.1 - 1e-08 35.1 6.2 1e-08 35.1 6.2 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDS34178.1 - 4.4e-08 31.7 13.7 3.1e-06 25.6 1.2 2.1 2 0 0 2 2 2 2 Patched family RRM_1 PF00076.22 CDS34179.1 - 4.2e-09 36.1 0.0 0.00073 19.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT16 PF08644.11 CDS34180.2 - 1.4e-57 194.1 0.3 1.4e-57 194.1 0.3 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CDS34180.2 - 2.3e-25 89.3 0.9 6.1e-25 87.9 0.9 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CDS34180.2 - 2.1e-19 70.0 0.0 5.6e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.12 CDS34180.2 - 3.4e-16 59.4 0.1 9.3e-16 58.0 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3713 PF12506.8 CDS34180.2 - 0.087 13.1 1.7 23 5.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) RGS PF00615.19 CDS34180.2 - 4.9 7.5 8.6 29 5.0 0.1 4.0 4 0 0 4 4 4 0 Regulator of G protein signaling domain ANAPC4_WD40 PF12894.7 CDS34181.2 - 1.6e-05 25.1 0.0 0.32 11.3 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 CDS34181.2 - 0.00019 21.1 0.0 6.9 6.2 0.2 4.1 3 1 0 3 3 3 2 CNH domain WD40 PF00400.32 CDS34181.2 - 0.001 19.9 0.5 27 5.9 0.1 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Hormone_3 PF00159.18 CDS34185.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide GHMP_kinases_C PF08544.13 CDS34186.1 - 4e-10 39.9 0.0 6.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal Hormone_3 PF00159.18 CDS34188.2 - 0.092 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide GalKase_gal_bdg PF10509.9 CDS34189.1 - 3.3e-20 71.4 0.0 5.4e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CDS34189.1 - 4.1e-15 55.9 0.0 1.1e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CDS34189.1 - 9.2e-13 48.2 0.4 2.3e-12 47.0 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain NAP PF00956.18 CDS34189.1 - 0.045 12.9 0.4 0.064 12.4 0.4 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Cid2 PF09774.9 CDS34190.1 - 7e-12 46.0 8.0 6.7e-10 39.6 8.0 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 MSP1_C PF07462.11 CDS34190.1 - 0.0025 16.6 0.1 0.0027 16.5 0.1 1.1 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Bestrophin PF01062.21 CDS34192.1 - 1.6e-61 208.3 6.1 3.1e-31 108.8 0.7 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel APC_u14 PF16635.5 CDS34192.1 - 0.0056 17.2 0.6 0.014 15.9 0.6 1.7 1 0 0 1 1 1 1 Unstructured region on APC between SAMP and APC_crr Bestrophin PF01062.21 CDS34194.2 - 6.3e-68 229.3 5.8 2e-34 119.3 0.6 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Sec7 PF01369.20 CDS34195.1 - 6.6e-61 205.2 0.1 1.2e-60 204.3 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDS34195.1 - 2.2e-20 73.1 11.3 2.4e-19 69.8 6.2 3.3 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.25 CDS34196.1 - 4.4e-34 118.0 0.0 5.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34196.1 - 3.7e-17 62.5 0.0 4.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDS34196.1 - 0.013 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Forkhead PF00250.18 CDS34197.1 - 1.5e-38 130.9 0.3 3.4e-38 129.8 0.1 1.7 2 0 0 2 2 2 1 Forkhead domain Transformer PF06495.11 CDS34197.1 - 0.022 14.9 5.1 0.038 14.1 5.1 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DIX PF00778.17 CDS34199.1 - 1.6e-32 111.2 0.0 3.5e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 DIX domain RGS PF00615.19 CDS34199.1 - 2.5e-19 69.7 0.0 1.3e-18 67.4 0.0 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.10 CDS34199.1 - 8e-19 67.5 1.4 8e-19 67.5 1.4 2.8 2 0 0 2 2 2 1 Axin beta-catenin binding domain Rad50_zn_hook PF04423.14 CDS34199.1 - 0.032 14.1 0.4 0.097 12.5 0.4 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2020 PF09449.10 CDS34199.1 - 4.6 7.1 7.0 0.53 10.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2020) Raptor_N PF14538.6 CDS34200.1 - 8.3e-63 210.7 0.0 1.9e-62 209.5 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CDS34200.1 - 4.8e-08 32.6 0.9 0.11 12.9 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CDS34200.1 - 0.0013 18.8 0.2 1.1 9.3 0.1 4.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.32 CDS34200.1 - 0.0027 18.5 0.0 6.9 7.7 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT_2 PF13646.6 CDS34200.1 - 0.039 14.3 0.0 7 7.1 0.0 4.1 2 1 0 2 2 2 0 HEAT repeats HEAT_PBS PF03130.16 CDS34200.1 - 1.2 10.0 3.3 1.3e+02 3.7 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat SelP_N PF04592.14 CDS34200.1 - 7.4 5.9 15.4 15 4.9 15.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TTL PF03133.15 CDS34203.2 - 3e-50 171.0 0.0 6.5e-50 169.9 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family PRMT5_C PF17286.2 CDS34203.2 - 0.13 12.1 1.1 3.4 7.5 1.3 2.3 2 0 0 2 2 2 0 PRMT5 oligomerisation domain BTB_3 PF16017.5 CDS34204.1 - 1.6e-32 111.8 0.1 9.1e-20 70.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB_2 PF02214.22 CDS34204.1 - 0.00023 21.5 0.0 0.53 10.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.15 CDS34205.1 - 4.8e-06 26.7 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1_POZ PF03931.15 CDS34206.1 - 7.3e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 CDS34206.1 - 0.062 13.5 0.1 0.079 13.2 0.1 1.2 1 0 0 1 1 1 0 BTB/POZ domain Ribosomal_L24e PF01246.20 CDS34207.1 - 1.1e-26 92.9 0.4 1.1e-26 92.9 0.4 2.5 2 1 2 4 4 4 1 Ribosomal protein L24e PIN_12 PF16289.5 CDS34207.1 - 2.5 8.5 5.1 3.5 8.1 5.1 1.1 1 0 0 1 1 1 0 PIN domain Mucin PF01456.17 CDS34208.1 - 0.84 9.6 9.7 0.068 13.2 2.8 2.0 1 1 1 2 2 2 0 Mucin-like glycoprotein EF-hand_7 PF13499.6 CDS34209.1 - 5.1e-12 46.1 2.0 6.7e-05 23.3 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS34209.1 - 5.8e-12 44.5 1.8 0.00019 21.1 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDS34209.1 - 1.2e-09 37.0 8.1 0.0007 19.0 0.0 4.0 4 0 0 4 4 4 2 EF hand UPF0154 PF03672.13 CDS34209.1 - 1.5e-05 24.9 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_8 PF13833.6 CDS34209.1 - 0.00019 21.2 3.2 0.55 10.1 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDS34209.1 - 0.00025 20.4 2.3 0.61 9.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 CDS34209.1 - 0.0033 18.3 0.0 0.0079 17.1 0.0 1.6 1 1 1 2 2 2 1 EF-hand domain ACCA PF03255.14 CDS34209.1 - 0.0081 16.0 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SurA_N_2 PF13623.6 CDS34209.1 - 0.033 14.1 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_9 PF14658.6 CDS34209.1 - 0.054 13.8 0.0 6.5 7.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Syntaxin PF00804.25 CDS34209.1 - 0.065 12.9 0.5 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Syntaxin WD40 PF00400.32 CDS34210.1 - 0.0083 17.0 3.1 0.64 11.0 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Cas_GSU0054 PF09609.10 CDS34211.2 - 0.093 11.4 0.1 0.26 9.9 0.0 1.6 1 1 1 2 2 2 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) PDCD7 PF16021.5 CDS34212.1 - 4.1e-11 42.6 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Programmed cell death protein 7 DUF4530 PF15039.6 CDS34212.1 - 0.031 14.4 0.2 0.047 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Annexin PF00191.20 CDS34213.2 - 4.1e-37 126.1 3.8 1.4e-15 57.1 0.3 4.8 4 1 0 4 4 4 4 Annexin Tubulin PF00091.25 CDS34215.1 - 4.8e-63 212.9 0.0 7.4e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS34215.1 - 1.2e-43 148.3 0.1 2e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDS34215.1 - 0.00044 20.5 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CDS34216.1 - 3.2e-66 223.3 0.0 4.4e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS34216.1 - 1.5e-50 170.6 0.0 2.3e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS34216.1 - 0.002 17.8 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF1664 PF07889.12 CDS34217.1 - 0.037 14.1 3.8 0.92 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 CDS34217.1 - 0.085 12.7 2.0 3.8 7.4 0.0 3.1 2 1 0 2 2 2 0 Synaptobrevin DUF2115 PF09888.9 CDS34217.1 - 0.23 12.0 1.8 0.35 11.4 0.3 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4307 PF14155.6 CDS34217.1 - 0.47 10.3 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Seryl_tRNA_N PF02403.22 CDS34217.1 - 0.61 10.4 8.9 2 8.7 1.8 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2951 PF11166.8 CDS34217.1 - 1.3 9.3 5.7 0.92 9.8 0.3 3.1 3 2 0 3 3 3 0 Protein of unknown function (DUF2951) Fer2 PF00111.27 CDS34218.1 - 2.6e-05 24.1 0.1 3.7e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF2373 PF10180.9 CDS34219.2 - 4.1e-20 71.4 0.1 6.9e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) vATP-synt_E PF01991.18 CDS34219.2 - 0.27 10.6 4.1 0.5 9.8 4.1 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit zf-C2H2 PF00096.26 CDS34220.1 - 1.6e-12 47.1 22.6 0.00024 21.4 5.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS34220.1 - 2.8e-10 40.1 7.5 1.1e-05 25.6 0.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS34220.1 - 3.7e-09 36.6 20.9 0.00033 21.2 4.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDS34220.1 - 0.011 16.0 6.1 0.026 14.8 4.9 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CDS34220.1 - 0.026 14.5 6.8 2 8.5 2.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDS34220.1 - 0.18 11.7 6.3 0.4 10.6 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type C5HCH PF17982.1 CDS34220.1 - 0.23 11.6 0.3 0.23 11.6 0.3 2.5 3 0 0 3 3 3 0 NSD Cys-His rich domain zf-C2H2_jaz PF12171.8 CDS34220.1 - 0.24 11.7 7.7 2 8.8 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CDS34220.1 - 0.61 10.8 7.3 2.8 8.6 0.3 3.5 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 CDS34220.1 - 1.5 9.5 6.8 3.4 8.4 1.8 2.8 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Tubulin_C PF03953.17 CDS34223.2 - 1e-50 171.1 0.0 1.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CDS34223.2 - 3.5e-12 46.9 0.0 5.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain UCH PF00443.29 CDS34224.1 - 5.9e-48 163.6 0.0 9.1e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS34224.1 - 1.3e-15 57.8 0.2 2.5e-15 56.9 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDS34224.1 - 1.3e-08 35.1 13.2 2.1e-08 34.4 8.5 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 CDS34224.1 - 0.0027 17.2 3.0 0.017 14.6 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Tubulin PF00091.25 CDS34225.1 - 4.1e-66 222.9 0.0 5.6e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS34225.1 - 2.3e-45 153.8 0.0 3.5e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Somatomedin_B PF01033.17 CDS34225.1 - 0.19 12.2 2.1 0.46 10.9 2.1 1.6 1 0 0 1 1 1 0 Somatomedin B domain Tubulin_2 PF13809.6 CDS34225.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like EMP70 PF02990.16 CDS34226.1 - 1.1e-146 489.5 13.7 1.5e-146 489.1 13.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Tubulin-binding PF00418.19 CDS34228.1 - 7.1e-38 128.3 10.6 7.7e-16 57.8 0.3 4.4 4 0 0 4 4 4 4 Tau and MAP protein, tubulin-binding repeat TPR_1 PF00515.28 CDS34229.1 - 3.3e-13 48.8 2.5 0.00073 19.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34229.1 - 8.9e-08 31.7 6.7 0.0084 16.1 0.2 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDS34229.1 - 5.2e-07 29.7 0.1 0.0018 18.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat RPAP3_C PF13877.6 CDS34229.1 - 7.3e-06 26.4 0.4 2.7e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.6 CDS34229.1 - 3.3e-05 24.3 0.7 0.32 11.5 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS34229.1 - 4.1e-05 24.1 0.3 0.18 12.5 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS34229.1 - 7.2e-05 22.8 3.1 0.011 15.8 0.2 3.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CDS34229.1 - 0.0014 18.8 0.6 0.0038 17.4 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDS34229.1 - 0.0031 17.4 0.2 0.65 10.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDS34229.1 - 0.0069 17.1 0.9 6.5 7.9 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDS34229.1 - 0.024 14.3 1.4 0.1 12.3 1.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 CDS34229.1 - 0.028 14.7 2.6 0.33 11.3 0.5 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDS34229.1 - 0.047 14.3 1.0 54 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3336 PF11815.8 CDS34229.1 - 0.054 13.2 0.9 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) TPR_17 PF13431.6 CDS34229.1 - 0.1 13.1 1.0 14 6.3 0.5 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS34229.1 - 0.14 12.0 0.3 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34229.1 - 0.39 11.0 6.3 2.9 8.3 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3337 PF11816.8 CDS34230.1 - 3.5e-29 101.9 0.0 4.9e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 CDS34230.1 - 5.8e-28 96.6 4.2 4.6e-06 27.3 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34230.1 - 2.8e-08 34.0 0.1 0.93 9.8 0.1 5.5 3 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDS34230.1 - 0.0023 16.8 0.1 0.39 9.4 0.0 3.2 2 1 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 CDS34230.1 - 0.0047 15.6 4.0 0.25 9.9 1.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 RAWUL PF16207.5 CDS34230.1 - 0.022 15.4 0.0 0.16 12.7 0.0 2.3 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like SDP_N PF12278.8 CDS34230.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal HLH PF00010.26 CDS34233.1 - 2.1e-14 53.2 0.1 5.4e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSNAXIP1_N PF15739.5 CDS34233.1 - 0.3 11.5 1.6 0.38 11.2 0.3 1.8 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus PAT1 PF09770.9 CDS34233.1 - 2.1 6.5 13.4 4 5.6 13.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CSRNP_N PF16019.5 CDS34234.1 - 5.3e-50 170.4 11.6 1.6e-36 126.3 5.4 2.3 2 0 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus TCR PF03638.15 CDS34234.1 - 0.42 11.0 11.5 1.2 9.5 11.5 1.8 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Bcl-2 PF00452.19 CDS34235.1 - 6.6e-08 33.2 0.2 2e-07 31.6 0.2 1.9 1 1 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family SPX PF03105.19 CDS34235.1 - 9.7 6.0 12.6 1.5 8.7 8.0 1.9 2 0 0 2 2 2 0 SPX domain Ribophorin_II PF05817.14 CDS34236.1 - 5.4e-161 537.3 0.5 6.3e-161 537.1 0.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II NADH_dhqG_C PF09326.11 CDS34237.2 - 0.025 15.3 0.5 0.08 13.6 0.5 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal zf-C3H1 PF10650.9 CDS34237.2 - 0.13 12.0 6.8 2.1 8.1 0.3 2.5 2 0 0 2 2 2 0 Putative zinc-finger domain Pkinase PF00069.25 CDS34238.2 - 6.6e-41 140.4 0.0 5.5e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34238.2 - 4.5e-31 108.1 0.0 9.3e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS34238.2 - 6.4e-05 21.9 0.0 6.4e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDS34238.2 - 0.00058 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CDS34238.2 - 0.078 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kelch_1 PF01344.25 CDS34239.1 - 1.5e-20 72.5 0.2 2e-11 43.3 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDS34239.1 - 2.3e-15 56.3 0.0 4.4e-09 36.3 0.0 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CDS34239.1 - 1.7e-09 37.7 0.3 5.1e-08 33.0 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CDS34239.1 - 1.7e-08 34.3 0.4 1.1e-06 28.5 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS34239.1 - 3.5e-05 23.6 0.0 0.0021 17.9 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CDS34239.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 2.6 4 0 0 4 4 4 1 Kelch motif DUF678 PF05077.12 CDS34239.1 - 0.044 13.9 5.3 0.57 10.4 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Kelch_1 PF01344.25 CDS34240.2 - 1.2e-22 79.3 0.0 7e-10 38.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CDS34240.2 - 7.9e-17 60.9 0.0 5.1e-07 29.7 0.0 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CDS34240.2 - 4.5e-10 39.4 0.1 1.6e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain BTB PF00651.31 CDS34240.2 - 4.6e-10 39.7 0.0 1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 CDS34240.2 - 2.4e-09 36.8 0.0 0.00035 20.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CDS34240.2 - 5.6e-09 36.1 0.2 2.4e-05 24.5 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain BACK PF07707.15 CDS34240.2 - 1.7e-07 31.3 0.0 1.9e-06 27.9 0.0 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CDS34240.2 - 3.9e-07 29.9 0.0 0.0034 17.3 0.0 4.1 4 0 0 4 4 4 1 Kelch motif CATSPERD PF15020.6 CDS34242.2 - 0.01 14.1 0.1 0.015 13.6 0.1 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Kelch_1 PF01344.25 CDS34244.2 - 4.5e-24 83.8 0.0 9.8e-11 41.1 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDS34244.2 - 7.1e-15 54.7 0.0 1.1e-07 31.9 0.0 3.6 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CDS34244.2 - 1e-09 38.2 0.0 3.7e-07 30.0 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS34244.2 - 1.2e-08 35.0 0.0 8.4e-07 29.1 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CDS34244.2 - 1.7e-07 30.9 0.1 4.1e-05 23.4 0.0 3.4 4 0 0 4 4 4 1 Kelch motif BTB PF00651.31 CDS34244.2 - 5.4e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CDS34244.2 - 2.3e-06 27.5 3.2 0.0037 17.2 0.0 4.1 4 1 0 4 4 4 2 Kelch motif CAP PF00188.26 CDS34245.1 - 1.5e-09 38.8 0.1 2.6e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CDS34246.1 - 7.2e-16 59.2 2.3 1.2e-15 58.4 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CDC45 PF02724.14 CDS34246.1 - 0.08 11.2 19.7 0.067 11.5 18.8 1.2 1 1 0 1 1 1 0 CDC45-like protein IFT57 PF10498.9 CDS34246.1 - 0.28 10.1 11.9 0.33 9.9 11.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2457 PF10446.9 CDS34246.1 - 1.1 8.3 23.0 1.3 8.0 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 CDS34246.1 - 1.1 7.3 25.1 1.3 7.0 25.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CDS34246.1 - 1.3 7.1 22.7 1.5 6.9 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 CDS34246.1 - 3.7 6.7 8.7 5.8 6.0 8.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 CDS34246.1 - 8.3 5.7 23.3 11 5.4 23.3 1.1 1 0 0 1 1 1 0 SDA1 TAP42 PF04177.12 CDS34247.1 - 0.014 14.6 0.3 0.017 14.3 0.3 1.2 1 0 0 1 1 1 0 TAP42-like family EF-hand_1 PF00036.32 CDS34248.1 - 5.7e-38 125.7 12.8 3.2e-09 35.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS34248.1 - 2.4e-33 114.4 3.5 8.3e-16 58.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDS34248.1 - 1.9e-30 102.2 5.6 9.5e-08 31.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDS34248.1 - 2.1e-26 90.2 10.3 6.8e-07 28.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDS34248.1 - 7.1e-26 89.8 14.4 1.9e-12 46.8 2.5 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDS34248.1 - 4.4e-14 52.5 0.0 2.2e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDS34248.1 - 4.1e-09 36.3 0.9 0.0012 18.8 0.1 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS34248.1 - 4.5e-07 30.2 0.0 0.0051 17.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CDS34248.1 - 7.4e-05 23.6 0.0 0.34 11.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CDS34248.1 - 0.00017 21.7 1.1 0.038 14.2 0.0 2.8 2 1 1 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 CDS34248.1 - 0.00027 20.9 0.2 0.55 10.1 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF1103 PF06513.11 CDS34248.1 - 0.00078 19.1 0.1 0.001 18.7 0.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF1456 PF07308.13 CDS34248.1 - 0.0066 16.8 0.6 4.1 7.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) UPF0154 PF03672.13 CDS34248.1 - 0.024 14.6 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CDS34248.1 - 0.04 14.0 0.3 0.31 11.2 0.0 2.6 3 1 0 3 3 3 0 Ca2+ insensitive EF hand DUF5580 PF17743.1 CDS34248.1 - 0.068 11.7 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_1 PF00036.32 CDS34249.2 - 3e-30 101.5 9.4 1.4e-07 30.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDS34249.2 - 2e-29 101.9 3.9 3.6e-16 59.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDS34249.2 - 5e-25 87.1 10.4 1.8e-11 43.7 0.0 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CDS34249.2 - 2.3e-23 80.1 10.8 9.8e-08 31.3 0.0 4.9 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CDS34249.2 - 5.4e-20 69.9 13.0 2.8e-06 26.6 0.0 4.9 4 1 1 5 5 5 4 EF hand EF-hand_4 PF12763.7 CDS34249.2 - 1.5e-07 31.3 1.3 0.0014 18.5 0.3 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDS34249.2 - 6.3e-07 29.6 0.0 0.005 17.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS34249.2 - 1e-06 29.0 0.1 0.012 15.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CDS34249.2 - 1.4e-05 25.1 0.2 0.12 12.3 0.0 3.0 2 1 1 3 3 3 2 Caleosin related protein Dockerin_1 PF00404.18 CDS34249.2 - 0.0017 18.5 4.5 0.11 12.7 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain UPF0154 PF03672.13 CDS34249.2 - 0.002 18.1 0.0 0.95 9.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) DUF5580 PF17743.1 CDS34249.2 - 0.0039 15.8 0.0 0.02 13.5 0.0 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5580) EFhand_Ca_insen PF08726.10 CDS34249.2 - 0.0095 16.0 0.4 0.21 11.7 0.0 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF4476 PF14771.6 CDS34249.2 - 0.033 14.5 2.6 2.6 8.4 0.1 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4476) DUF1636 PF07845.11 CDS34249.2 - 0.086 13.3 0.0 16 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) MH2 PF03166.14 CDS34250.1 - 1e-21 78.1 0.0 4.9e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 MH2 domain Mad3_BUB1_I_2 PF17014.5 CDS34251.2 - 0.013 15.6 0.5 0.013 15.6 0.5 2.0 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Filament PF00038.21 CDS34251.2 - 0.017 14.7 4.4 0.024 14.2 4.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein FAM184 PF15665.5 CDS34251.2 - 0.058 13.2 4.2 0.083 12.7 4.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PKK PF12474.8 CDS34251.2 - 1 9.5 7.6 1.4 9.0 7.6 1.2 1 0 0 1 1 1 0 Polo kinase kinase DUF2070 PF09843.9 CDS34252.1 - 6.3 5.0 7.7 7.6 4.7 7.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMEM43 PF07787.12 CDS34252.1 - 7.8 5.8 5.6 11 5.3 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 LRR19-TM PF15176.6 CDS34253.1 - 0.37 10.8 4.4 0.12 12.4 1.2 1.9 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2070 PF09843.9 CDS34253.1 - 0.67 8.2 3.2 0.84 7.8 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TTL PF03133.15 CDS34255.2 - 1.5e-86 290.2 0.5 2.7e-86 289.4 0.5 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CDS34255.2 - 1.2e-07 31.3 0.1 5.2e-05 22.6 0.0 3.1 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CDS34255.2 - 0.0058 15.9 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp MFS_1 PF07690.16 CDS34256.2 - 7e-28 97.6 72.4 3.1e-15 56.0 14.4 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 CDS34256.2 - 2.4e-05 23.8 16.3 2.4e-05 23.8 16.3 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4820 PF16091.5 CDS34256.2 - 0.68 9.2 4.8 1.5 8.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 CDS34256.2 - 2.8 7.9 5.1 5.3 7.0 5.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 CDS34258.1 - 2.2e-26 92.6 50.7 4.5e-17 62.0 23.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily UPF0239 PF06783.11 CDS34258.1 - 4.5 7.5 5.8 13 6.1 0.2 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) MFS_1 PF07690.16 CDS34259.1 - 4.6e-35 121.2 31.3 2.2e-28 99.2 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDS34259.1 - 0.00023 20.2 9.2 0.00023 20.2 9.2 3.0 3 0 0 3 3 3 2 MFS_1 like family MFS_1 PF07690.16 CDS34260.2 - 1.5e-15 57.0 32.7 1.5e-15 57.0 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily KTI12 PF08433.10 CDS34261.2 - 3.1e-38 131.8 1.7 4.4e-30 105.1 0.1 2.4 1 1 1 2 2 2 2 Chromatin associated protein KTI12 WD40 PF00400.32 CDS34261.2 - 2.6e-19 69.2 12.1 0.0046 17.8 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.12 CDS34261.2 - 1.1e-16 61.1 0.2 2.7e-16 59.8 0.2 1.8 1 0 0 1 1 1 1 NLE (NUC135) domain AAA_33 PF13671.6 CDS34261.2 - 8e-11 42.3 0.1 2.2e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 CDS34261.2 - 1.1e-05 25.6 0.5 0.43 10.9 0.0 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_18 PF13238.6 CDS34261.2 - 0.00015 22.3 0.1 0.00053 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.18 CDS34261.2 - 0.00022 20.6 0.2 0.00043 19.7 0.2 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_28 PF13521.6 CDS34261.2 - 0.0023 18.2 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPSF_A PF03178.15 CDS34261.2 - 0.0092 15.3 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region PRK PF00485.18 CDS34261.2 - 0.022 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 CDS34261.2 - 0.026 13.9 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CDS34261.2 - 0.049 14.0 0.4 0.12 12.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDS34261.2 - 0.064 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDS34261.2 - 0.068 13.6 0.0 0.73 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain YTH PF04146.15 CDS34262.1 - 5.1e-40 137.1 0.7 1.3e-39 135.9 0.7 1.7 1 1 0 1 1 1 1 YT521-B-like domain 7tm_1 PF00001.21 CDS34265.2 - 1.2e-41 142.8 3.4 1.2e-41 142.8 3.4 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS34265.2 - 0.0072 15.7 7.8 0.013 14.9 7.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FixQ PF05545.11 CDS34265.2 - 8.6 6.4 9.8 11 6.0 0.6 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_S24 PF00717.23 CDS34266.1 - 4.6e-09 36.1 0.1 8.3e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CDS34266.1 - 7.8e-06 25.7 0.0 0.005 16.6 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF2635 PF10948.8 CDS34266.1 - 0.076 12.8 0.4 0.79 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Ufm1 PF03671.14 CDS34267.1 - 1.6e-38 130.7 0.0 2.1e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein TB2_DP1_HVA22 PF03134.19 CDS34268.1 - 4.4e-15 55.4 1.3 7.2e-15 54.7 1.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PP2C_2 PF13672.6 CDS34271.1 - 3.8e-07 30.0 0.1 7.5e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CDS34271.1 - 0.052 13.2 0.9 0.24 11.0 0.0 2.5 4 0 0 4 4 4 0 Protein phosphatase 2C Adaptin_N PF01602.20 CDS34272.1 - 5.1e-124 414.7 5.9 5.7e-124 414.5 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDS34272.1 - 4.4e-08 33.3 1.2 2.3e-06 27.7 0.0 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDS34272.1 - 3.5e-05 24.1 2.1 0.00075 19.8 0.1 3.5 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CDS34272.1 - 0.001 19.2 6.3 39 4.9 0.1 6.5 6 1 1 7 7 7 0 HEAT repeat IFRD PF05004.13 CDS34272.1 - 0.002 17.3 2.1 0.095 11.8 1.1 2.3 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CDS34272.1 - 0.34 11.1 3.5 2.5 8.3 0.0 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-Tim10_DDP PF02953.15 CDS34273.1 - 1.3e-18 66.3 0.9 1.8e-18 65.9 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Oscp1 PF10188.9 CDS34273.1 - 0.032 14.3 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Organic solute transport protein 1 DUF1115 PF06544.12 CDS34278.1 - 0.03 14.4 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Parvo_NS1 PF01057.17 CDS34279.1 - 2.2e-12 46.7 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CDS34279.1 - 1.5e-05 24.0 0.0 1.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase Torsin PF06309.11 CDS34279.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Torsin GyrB_insert PF18053.1 CDS34279.1 - 0.14 12.1 0.1 6.5 6.6 0.0 2.4 2 1 1 3 3 3 0 DNA gyrase B subunit insert domain Anoctamin PF04547.12 CDS34283.2 - 2.1e-54 185.1 13.3 2.6e-54 184.7 13.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CDS34283.2 - 3e-22 79.5 0.0 3.2e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Oleosin PF01277.17 CDS34283.2 - 0.67 9.7 0.0 0.67 9.7 0.0 3.3 4 0 0 4 4 4 0 Oleosin DUF778 PF05608.12 CDS34286.1 - 1.9e-37 129.5 3.0 4.5e-22 79.3 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CDS34286.1 - 0.015 14.9 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-C2H2 PF00096.26 CDS34288.2 - 2.9e-05 24.3 13.0 0.0041 17.5 0.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS34288.2 - 0.00027 21.2 10.5 0.0097 16.3 1.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS34288.2 - 0.0059 17.3 0.5 0.0059 17.3 0.5 3.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDS34288.2 - 0.0078 16.5 3.4 0.03 14.6 3.4 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDS34288.2 - 0.017 15.5 0.3 0.017 15.5 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribonuc_red_2_N PF08471.10 CDS34288.2 - 0.037 14.2 0.2 0.094 12.9 0.2 1.6 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase zf-C2H2_9 PF16293.5 CDS34288.2 - 0.048 13.5 1.4 0.35 10.7 0.1 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 CDS34288.2 - 0.055 13.5 0.5 0.055 13.5 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDS34288.2 - 0.19 12.1 0.1 0.19 12.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CDS34288.2 - 6.8 7.1 7.7 2.7 8.4 3.3 2.5 2 1 0 2 2 2 0 C2H2-type zinc ribbon Ras PF00071.22 CDS34289.1 - 1.6e-62 209.9 0.3 2.1e-62 209.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS34289.1 - 4.4e-34 117.3 0.3 1.1e-33 116.0 0.1 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS34289.1 - 4.4e-16 58.8 0.0 5.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDS34289.1 - 2.9e-06 26.8 0.2 5.1e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDS34289.1 - 1.4e-05 25.1 0.1 0.38 10.6 0.1 3.0 2 1 1 3 3 3 3 RsgA GTPase MMR_HSR1 PF01926.23 CDS34289.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDS34289.1 - 2.4e-05 23.9 0.0 3.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDS34289.1 - 0.00035 20.2 0.2 0.00064 19.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CDS34289.1 - 0.0019 18.0 0.3 0.0031 17.3 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 CDS34289.1 - 0.04 13.9 0.2 0.35 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CDS34289.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 CDS34289.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 CDS34289.1 - 0.099 12.4 0.1 0.22 11.3 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDS34289.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PPV_E2_C PF00511.17 CDS34289.1 - 0.14 12.3 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 E2 (early) protein, C terminal Ski_Sno PF02437.17 CDS34290.1 - 1.2e-34 118.2 0.0 2.6e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family RYDR_ITPR PF01365.21 CDS34291.2 - 4.2e-83 277.8 0.0 3e-82 275.0 0.0 2.6 3 0 0 3 3 3 1 RIH domain RyR PF02026.16 CDS34291.2 - 1.2e-46 156.8 0.0 7.2e-23 80.6 0.0 2.7 2 0 0 2 2 2 2 RyR domain RR_TM4-6 PF06459.12 CDS34291.2 - 6.2e-35 121.4 0.3 3.5e-34 118.9 0.0 2.2 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 RIH_assoc PF08454.11 CDS34291.2 - 1e-32 112.0 0.9 1.4e-30 105.1 0.1 3.8 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ion_trans PF00520.31 CDS34291.2 - 2.3e-12 46.7 6.7 2.3e-12 46.7 6.7 1.9 2 0 0 2 2 2 1 Ion transport protein EF-hand_7 PF13499.6 CDS34291.2 - 1e-11 45.1 0.8 3.4e-11 43.4 0.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CDS34291.2 - 4.7e-09 35.3 0.2 0.0046 16.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 CDS34291.2 - 1.9e-07 30.1 0.6 0.0026 17.2 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDS34291.2 - 5.8e-06 26.1 0.1 1.6e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CDS34291.2 - 6.7e-06 25.6 0.2 0.005 16.7 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain DUF996 PF06195.13 CDS34291.2 - 0.074 13.3 3.9 0.16 12.3 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) EMP24_GP25L PF01105.24 CDS34292.1 - 4.6e-32 111.4 0.6 5.2e-32 111.3 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TPR_12 PF13424.6 CDS34293.2 - 6.5e-21 74.4 30.1 1.3e-07 31.8 0.6 6.3 3 2 1 6 6 6 5 Tetratricopeptide repeat GoLoco PF02188.17 CDS34293.2 - 9.1e-19 66.6 22.1 1.4e-07 30.8 0.8 3.6 3 0 0 3 3 3 3 GoLoco motif TPR_7 PF13176.6 CDS34293.2 - 1.8e-17 62.0 25.3 7e-05 22.6 0.1 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDS34293.2 - 9.1e-16 56.9 33.1 0.00057 19.6 0.1 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34293.2 - 2.1e-11 43.0 31.3 0.093 12.9 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34293.2 - 1.4e-09 37.4 23.5 0.028 14.6 0.3 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 CDS34293.2 - 1.8e-09 37.2 28.2 0.0059 16.4 0.1 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat Rapsyn_N PF10579.9 CDS34293.2 - 0.00013 22.0 0.3 0.015 15.3 0.0 3.1 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 CDS34293.2 - 0.00054 20.6 12.6 0.69 10.9 0.2 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS34293.2 - 0.022 14.1 8.8 0.063 12.6 3.8 2.8 2 1 0 2 2 2 0 MalT-like TPR region COX5A PF02284.16 CDS34293.2 - 0.047 13.7 0.2 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va TPR_17 PF13431.6 CDS34293.2 - 0.11 12.9 10.5 17 6.0 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDS34293.2 - 0.16 12.7 20.4 0.25 12.1 0.8 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDS34293.2 - 3.5 7.4 21.4 4.6 7.0 0.4 6.3 6 1 0 6 6 6 0 TPR repeat Glypican PF01153.19 CDS34294.2 - 2.6e-20 72.8 1.0 1.3e-19 70.5 0.1 2.2 2 1 0 2 2 2 1 Glypican Acetyltransf_1 PF00583.25 CDS34295.2 - 4.1e-08 33.5 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDS34295.2 - 2.3e-05 24.7 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDS34295.2 - 0.00049 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDS34295.2 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PA28_beta PF02252.18 CDS34296.1 - 2.3e-58 196.0 1.1 3.2e-58 195.5 1.1 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CDS34296.1 - 6.7e-13 48.5 0.1 1.1e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Cystatin PF00031.21 CDS34299.2 - 0.0052 17.0 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Cystatin domain Peptidase_C14 PF00656.22 CDS34299.2 - 0.11 12.4 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Cu_amine_oxid PF01179.20 CDS34301.1 - 1.7e-61 208.4 0.0 2.6e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CDS34301.1 - 0.12 12.8 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain B56 PF01603.20 CDS34302.1 - 5e-192 638.4 0.4 5.9e-192 638.2 0.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CDS34302.1 - 0.012 15.5 2.3 1.8 8.4 0.3 2.9 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CagE_TrbE_VirB PF03135.14 CDS34302.1 - 0.056 13.5 0.1 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system FNIP_N PF14636.6 CDS34302.1 - 6.7 7.7 7.3 0.83 10.6 1.6 2.2 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus RRM_1 PF00076.22 CDS34303.2 - 4e-20 71.4 0.0 5.8e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS34303.2 - 0.034 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDS34303.2 - 0.15 12.2 0.1 0.24 11.5 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 IFT20 PF14931.6 CDS34304.1 - 4.9e-32 110.6 7.8 6e-32 110.3 7.8 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Atg14 PF10186.9 CDS34304.1 - 0.00024 20.3 3.9 0.00026 20.2 3.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 CDS34304.1 - 0.0017 18.6 2.8 0.0023 18.1 2.8 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CDS34304.1 - 0.0018 17.2 5.4 0.002 17.1 5.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5082 PF16888.5 CDS34304.1 - 0.0081 16.4 1.2 0.014 15.7 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Phage_GPO PF05929.11 CDS34304.1 - 0.018 14.7 2.4 0.018 14.7 2.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MIP-T3 PF10243.9 CDS34304.1 - 0.02 14.9 0.2 0.027 14.4 0.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain T3SSipB PF16535.5 CDS34304.1 - 0.054 14.0 2.1 0.071 13.6 2.1 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 CDS34304.1 - 0.074 13.1 9.5 4.2 7.4 8.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 CDS34304.1 - 0.095 12.3 3.0 0.11 12.1 3.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CDS34304.1 - 0.15 12.1 2.1 0.2 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 CDS34304.1 - 0.55 10.9 7.0 9.8 6.9 5.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA EMP24_GP25L PF01105.24 CDS34304.1 - 0.88 9.5 6.1 7 6.6 6.6 1.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 CDS34304.1 - 1.3 9.5 4.6 21 5.7 4.6 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CDS34304.1 - 1.7 9.1 5.6 2e+02 2.5 5.6 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) GrpE PF01025.19 CDS34304.1 - 3 7.5 9.0 9.5 5.9 7.8 1.9 1 1 0 2 2 2 0 GrpE Spc24 PF08286.11 CDS34304.1 - 7.7 6.8 8.8 26 5.1 8.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LIM PF00412.22 CDS34305.1 - 6.7e-18 64.7 29.6 2.9e-12 46.6 8.0 2.5 2 0 0 2 2 2 2 LIM domain Homeodomain PF00046.29 CDS34305.1 - 6.6e-15 54.7 4.6 1.2e-14 53.9 4.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDS34305.1 - 0.0032 17.3 0.5 0.0083 16.0 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Dpy19 PF10034.9 CDS34306.2 - 3.2e-175 584.0 0.1 1.9e-105 353.5 0.0 4.4 3 1 0 3 3 3 3 Q-cell neuroblast polarisation Vert_HS_TF PF06546.11 CDS34306.2 - 0.02 14.6 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor BPS1 PF05633.11 CDS34306.2 - 0.069 12.1 0.2 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein BYPASS1-related MWFE PF15879.5 CDS34306.2 - 0.17 12.0 0.0 69 3.7 0.0 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit Peptidase_S8 PF00082.22 CDS34307.1 - 2.9e-41 141.7 3.5 3.7e-41 141.3 3.5 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CDS34307.1 - 3.1e-19 68.8 0.0 8e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CDS34307.1 - 3.8e-11 43.6 0.1 8e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Golgin_A5 PF09787.9 CDS34308.2 - 1.8e-13 50.7 13.3 1.8e-13 50.7 13.3 5.0 4 1 1 5 5 5 2 Golgin subfamily A member 5 V-SNARE_C PF12352.8 CDS34308.2 - 6e-05 23.2 2.2 6e-05 23.2 2.2 3.6 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus zf-RING_5 PF14634.6 CDS34308.2 - 7.2e-05 22.7 3.7 0.00016 21.5 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDS34308.2 - 0.0001 22.1 5.2 0.00024 20.9 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3772 PF12607.8 CDS34308.2 - 0.00013 21.6 3.3 0.16 11.8 0.3 3.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3772) Prok-RING_4 PF14447.6 CDS34308.2 - 0.00038 20.3 3.6 0.00093 19.0 3.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDS34308.2 - 0.00096 18.9 5.8 0.0022 17.8 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS34308.2 - 0.0019 18.0 3.2 0.0038 17.1 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS34308.2 - 0.002 18.4 3.7 0.0049 17.2 3.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CDS34308.2 - 0.012 15.6 0.6 0.028 14.4 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SNAP-25 PF00835.19 CDS34308.2 - 0.016 15.5 1.1 0.067 13.5 1.1 2.1 1 0 0 1 1 1 0 SNAP-25 family zf-C3HC4_4 PF15227.6 CDS34308.2 - 0.017 15.3 4.1 0.039 14.1 4.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CDS34308.2 - 0.18 11.7 0.6 0.43 10.5 0.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CDS34308.2 - 0.21 11.9 3.7 0.58 10.5 3.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDS34308.2 - 0.21 11.4 3.2 0.53 10.1 3.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GLE1 PF07817.13 CDS34308.2 - 1.2 8.3 10.9 0.15 11.2 5.8 2.1 2 0 0 2 2 2 0 GLE1-like protein RcpB PF16971.5 CDS34308.2 - 1.8 8.4 7.4 0.88 9.4 3.6 2.2 2 0 0 2 2 2 0 Rough colony protein B, tight adherence - tad - subunit zf-RING_UBOX PF13445.6 CDS34308.2 - 3.7 7.7 10.0 0.53 10.4 4.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Golgin_A5 PF09787.9 CDS34309.1 - 2.2e-07 30.7 0.2 2.2e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-C3HC4 PF00097.25 CDS34310.1 - 7.8e-08 32.1 9.9 2.5e-07 30.5 9.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDS34310.1 - 6.1e-07 29.2 6.6 1.4e-06 28.0 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS34310.1 - 7.9e-07 29.3 8.7 7.9e-07 29.3 8.7 2.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDS34310.1 - 5.1e-06 26.2 9.8 5.1e-06 26.2 9.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS34310.1 - 2.7e-05 24.1 5.1 2.7e-05 24.1 5.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 CDS34310.1 - 0.00024 21.2 7.1 0.00024 21.2 7.1 2.1 1 1 1 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDS34310.1 - 0.00074 19.3 8.7 0.0026 17.5 8.7 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CDS34310.1 - 0.00096 19.1 9.2 0.00096 19.1 9.2 2.4 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDS34310.1 - 0.0025 17.6 7.7 0.0025 17.6 7.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CDS34310.1 - 0.0047 17.0 11.2 0.02 15.1 11.2 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDS34310.1 - 0.047 13.5 6.8 0.14 12.0 6.8 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.6 CDS34310.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_11 PF17123.5 CDS34310.1 - 1.5 8.6 10.6 2.5 7.9 6.4 2.8 1 1 1 2 2 2 0 RING-like zinc finger DZR PF12773.7 CDS34310.1 - 2.4 8.2 14.1 0.37 10.8 7.9 2.9 3 1 0 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CDS34310.1 - 2.8 8.0 11.0 0.18 11.8 5.2 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 CDS34310.1 - 2.9 8.1 8.5 0.49 10.5 4.1 2.0 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 CDS34310.1 - 7.7 6.5 12.0 0.064 13.1 1.6 2.6 2 1 1 3 3 3 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.6 CDS34311.1 - 0.057 13.4 0.3 0.057 13.4 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS34311.1 - 0.19 11.6 5.5 0.95 9.3 0.1 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-FCS PF06467.14 CDS34311.1 - 1.9 8.5 8.9 1.3 9.1 0.4 2.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Med17 PF10156.9 CDS34313.1 - 0.029 13.1 0.7 0.034 12.9 0.7 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Pinin_SDK_memA PF04696.13 CDS34317.1 - 2.1e-28 99.0 13.6 2.1e-28 99.0 13.6 1.6 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Pinin_SDK_N PF04697.13 CDS34317.1 - 0.00068 20.3 0.2 0.00068 20.3 0.2 3.6 2 1 2 4 4 4 2 pinin/SDK conserved region AAA_11 PF13086.6 CDS34317.1 - 0.21 11.3 12.1 0.34 10.6 12.1 1.5 1 1 0 1 1 1 0 AAA domain TBCC PF07986.12 CDS34318.1 - 4.9e-22 77.9 0.6 7.7e-22 77.3 0.6 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CDS34318.1 - 3.4e-14 53.3 4.9 1.9e-13 50.9 4.9 2.1 1 1 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain ATP-synt_D PF01813.17 CDS34319.1 - 5.1e-67 225.5 2.0 6.8e-67 225.1 2.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Semialdhyde_dhC PF02774.18 CDS34319.1 - 0.072 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Tubulin PF00091.25 CDS34320.1 - 2.2e-68 230.4 0.0 3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS34320.1 - 4.6e-52 175.5 0.0 7.5e-52 174.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS34320.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_C PF03953.17 CDS34321.2 - 5.4e-16 58.9 0.1 7.3e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Cdc13_OB4_dimer PF18233.1 CDS34321.2 - 0.093 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain Tubulin PF00091.25 CDS34322.2 - 1.1e-68 231.3 0.0 1.5e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDS34322.2 - 3.7e-52 175.8 0.0 5.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDS34322.2 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Mlh1_C PF16413.5 CDS34323.1 - 4.4e-72 242.7 0.1 6.3e-72 242.2 0.1 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDS34323.1 - 7.1e-21 74.1 0.0 6.7e-20 71.0 0.0 2.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDS34323.1 - 8.1e-10 38.7 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDS34323.1 - 7.9e-06 26.3 0.0 2.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Colicin_V PF02674.16 CDS34325.1 - 0.016 15.2 0.4 0.02 14.9 0.4 1.1 1 0 0 1 1 1 0 Colicin V production protein PRA1 PF03208.19 CDS34325.1 - 0.022 14.4 0.6 0.029 14.0 0.6 1.1 1 0 0 1 1 1 0 PRA1 family protein VGCC_alpha2 PF08473.11 CDS34325.1 - 0.092 11.5 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd HEV_ORF1 PF02444.16 CDS34325.1 - 3.9 8.1 14.9 1.7 9.3 2.2 2.3 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) WD40 PF00400.32 CDS34326.1 - 0.00074 20.3 3.9 3.5 8.6 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat SOCS_box PF07525.16 CDS34326.1 - 0.2 12.1 0.1 0.38 11.2 0.1 1.4 1 0 0 1 1 1 0 SOCS box Neur_chan_memb PF02932.16 CDS34326.1 - 0.62 10.1 2.3 0.98 9.4 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SH2 PF00017.24 CDS34328.1 - 1.1e-23 83.1 0.0 2.1e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.27 CDS34328.1 - 1.3e-14 54.3 0.1 3.7e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CDS34328.1 - 9.4e-09 35.0 23.7 6.3e-05 22.8 4.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SAM_2 PF07647.17 CDS34328.1 - 1.4e-05 25.1 0.1 0.00035 20.6 0.0 2.9 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDS34328.1 - 4.2e-05 23.9 0.0 0.00028 21.3 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH2_2 PF14633.6 CDS34328.1 - 0.00042 19.8 0.0 0.0033 16.9 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Zf_RING PF16744.5 CDS34328.1 - 4.3 7.5 17.5 4.1 7.6 2.2 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_9 PF13901.6 CDS34328.1 - 8.7 6.3 20.5 9 6.2 10.3 2.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon 7tm_1 PF00001.21 CDS34329.1 - 1e-23 84.0 15.4 1.4e-23 83.5 15.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CDS34329.1 - 2.3e-06 27.2 14.1 1.7e-05 24.3 14.1 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PIP5K PF01504.18 CDS34329.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2070 PF09843.9 CDS34329.1 - 2 6.6 14.1 1.8 6.8 12.6 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Orf78 PF06024.12 CDS34329.1 - 6.2 7.2 9.6 6.1 7.2 0.6 2.9 3 0 0 3 3 3 0 Orf78 (ac78) M16C_assoc PF08367.11 CDS34330.2 - 1.3e-56 191.5 0.0 2.2e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CDS34330.2 - 4e-24 85.6 0.0 5.9e-18 65.5 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDS34330.2 - 6e-09 36.0 0.0 2.1e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3135 PF11333.8 CDS34331.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Dimer_Tnp_hAT PF05699.14 CDS34333.1 - 1.9e-08 34.0 0.1 5.5e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CDS34333.1 - 4.8e-07 29.7 0.2 1.1e-06 28.6 0.2 1.7 1 0 0 1 1 1 1 BED zinc finger Endonuc-FokI_C PF09254.11 CDS34333.1 - 0.26 10.6 0.2 0.5 9.6 0.2 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal SNF2_N PF00176.23 CDS34334.1 - 2.6e-62 210.6 0.0 4.7e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDS34334.1 - 1.8e-18 66.9 0.0 4e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 CDS34334.1 - 1.6e-14 53.6 16.2 2.4e-10 40.1 0.6 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain BRK PF07533.16 CDS34334.1 - 1.2e-09 37.6 0.2 3.4e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 BRK domain ResIII PF04851.15 CDS34334.1 - 1.4e-07 31.7 0.0 4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDS34334.1 - 0.028 13.6 0.0 0.18 11.0 0.1 2.2 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Prenyltrans PF00432.21 CDS34335.1 - 1.4e-42 143.1 13.2 1.8e-10 40.4 0.1 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CDS34335.1 - 0.0068 15.5 0.0 0.26 10.3 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CDS34335.1 - 0.016 14.3 0.0 0.084 11.9 0.0 2.0 1 1 2 3 3 3 0 Squalene-hopene cyclase N-terminal domain Gar1 PF04410.14 CDS34336.1 - 8.8e-19 67.8 3.0 1.4e-12 47.6 0.0 2.7 3 1 1 4 4 4 2 Gar1/Naf1 RNA binding region TMEM119 PF15724.5 CDS34336.1 - 0.79 9.7 6.6 0.12 12.5 2.5 1.6 2 0 0 2 2 2 0 TMEM119 family DEAD PF00270.29 CDS34337.1 - 2.4e-25 89.3 0.1 7.4e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS34337.1 - 1.6e-24 86.4 0.0 3.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS34337.1 - 0.0093 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Erythro-docking PF09277.11 CDS34337.1 - 0.083 12.8 1.9 3.8 7.5 0.0 3.3 2 1 1 3 3 3 0 Erythronolide synthase, docking Rubredoxin_C PF18267.1 CDS34337.1 - 0.11 12.4 0.1 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain ParD_antitoxin PF03693.14 CDS34337.1 - 0.7 10.3 3.4 3.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PCMT PF01135.19 CDS34338.2 - 1.5e-15 57.5 0.0 1.7e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CDS34338.2 - 0.011 14.8 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_anti-codon PF01336.25 CDS34339.1 - 0.014 15.3 0.2 0.032 14.2 0.2 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CDS34339.1 - 0.19 11.4 0.4 0.32 10.7 0.4 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 FUSC PF04632.12 CDS34339.1 - 0.34 9.4 2.4 0.36 9.3 1.3 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family ubiquitin PF00240.23 CDS34340.1 - 1.1e-08 34.7 0.1 2.7e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CDS34340.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDS34340.1 - 0.035 14.7 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MinE PF03776.14 CDS34340.1 - 0.19 11.8 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE SAPS PF04499.15 CDS34341.1 - 1.2e-18 67.3 4.2 1e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein TPR_1 PF00515.28 CDS34343.1 - 4.4e-08 32.6 4.5 0.055 13.3 0.0 3.9 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34343.1 - 0.0011 18.9 0.8 0.21 11.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34343.1 - 0.057 13.6 7.4 5.5 7.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34343.1 - 0.15 12.6 3.4 4.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS34343.1 - 0.17 12.0 1.6 0.86 9.7 0.2 2.8 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CDS34343.1 - 0.47 10.2 6.6 3 7.6 0.9 3.9 3 0 0 3 3 3 0 TPR repeat Piezo_RRas_bdg PF12166.8 CDS34344.1 - 3.5e-123 412.1 2.0 5.8e-123 411.3 2.0 1.4 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 CDS34344.1 - 1.8e-30 106.2 6.8 2.9e-26 92.3 0.7 3.5 2 1 1 3 3 3 2 Piezo MCM PF00493.23 CDS34345.1 - 1.5e-98 328.3 0.0 3e-98 327.4 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDS34345.1 - 4.7e-30 104.0 0.1 8.3e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDS34345.1 - 3.4e-18 65.8 4.2 8.5e-18 64.6 4.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDS34345.1 - 2.3e-16 60.3 1.6 3.7e-16 59.6 0.8 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDS34345.1 - 4.7e-07 29.4 0.0 1.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDS34345.1 - 5.7e-05 23.1 0.0 0.00018 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CDS34345.1 - 0.0046 16.7 0.0 0.024 14.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_lid_2 PF17863.1 CDS34345.1 - 0.066 13.1 4.0 0.073 12.9 0.9 2.5 2 0 0 2 2 2 0 AAA lid domain E1-E2_ATPase PF00122.20 CDS34346.1 - 6.1e-38 130.1 0.6 1.5e-37 128.8 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDS34346.1 - 6.2e-15 56.1 0.0 1.4e-07 32.0 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 CDS34346.1 - 1.1e-11 44.9 0.4 4.2e-11 43.0 0.4 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.21 CDS34346.1 - 7.2e-06 25.8 12.7 0.00022 21.0 11.8 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDS34346.1 - 2.8e-05 24.1 0.0 9e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Vps39_1 PF10366.9 CDS34346.1 - 0.0048 17.2 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Cation_ATPase_N PF00690.26 CDS34346.1 - 0.023 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF4491 PF14898.6 CDS34346.1 - 0.084 13.3 0.1 0.41 11.1 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Aminotran_5 PF00266.19 CDS34348.1 - 3.9e-91 305.8 0.0 4.5e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDS34348.1 - 8.1e-07 28.6 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CDS34348.1 - 6.6e-06 25.7 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CDS34348.1 - 0.01 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CDS34348.1 - 0.021 13.4 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CH PF00307.31 CDS34349.1 - 1.1e-07 32.0 0.1 2.9e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain ASH PF15780.5 CDS34349.1 - 2.3e-05 24.5 0.0 3.7 7.8 0.0 5.1 5 1 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CAMSAP_CH PF11971.8 CDS34349.1 - 0.00022 21.0 0.0 0.00078 19.2 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain DUF5060 PF16586.5 CDS34349.1 - 0.044 14.1 0.0 2.4 8.6 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) ASH PF15780.5 CDS34350.2 - 6e-05 23.2 0.8 5.4 7.3 0.0 4.2 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CDS34350.2 - 0.013 15.4 2.7 0.029 14.2 0.0 2.8 3 0 0 3 3 3 0 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CDS34350.2 - 0.11 12.8 0.6 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 131-like SAM_1 PF00536.30 CDS34351.2 - 2.9e-09 37.2 0.0 5.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDS34351.2 - 0.00029 20.9 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_2 PF12796.7 CDS34353.1 - 3.5e-43 146.1 9.5 1.5e-11 44.7 0.2 4.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS34353.1 - 8.8e-25 86.8 2.8 0.00012 22.6 0.0 6.0 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS34353.1 - 3.6e-23 79.1 10.1 0.0014 19.0 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDS34353.1 - 9e-23 79.7 11.3 0.00039 20.7 0.0 8.2 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 CDS34353.1 - 4e-20 71.6 8.0 3.7e-05 23.9 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) bZIP_1 PF00170.21 CDS34354.1 - 4.1e-11 42.8 13.5 7.5e-11 42.0 13.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CDS34354.1 - 2.4e-07 31.2 7.4 4.2e-07 30.4 7.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CDS34354.1 - 4.2e-07 29.9 14.1 6.7e-07 29.3 14.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper ASD2 PF08687.11 CDS34354.1 - 0.00015 21.5 0.5 0.00017 21.2 0.5 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Macoilin PF09726.9 CDS34354.1 - 0.0036 15.9 3.7 0.0041 15.8 3.7 1.0 1 0 0 1 1 1 1 Macoilin family UPF0242 PF06785.11 CDS34354.1 - 0.0037 17.4 1.6 0.0046 17.1 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus GCN5L1 PF06320.13 CDS34354.1 - 0.0077 16.4 1.0 0.013 15.6 1.0 1.4 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) ZapB PF06005.12 CDS34354.1 - 0.012 16.0 6.3 0.013 15.9 4.9 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Phlebovirus_NSM PF07246.11 CDS34354.1 - 0.039 13.3 1.8 0.056 12.8 1.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GIT_CC PF16559.5 CDS34354.1 - 0.063 13.2 3.6 0.14 12.0 3.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 CDS34354.1 - 0.066 13.2 6.2 0.1 12.6 6.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CDS34354.1 - 0.068 12.5 1.8 0.1 12.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 CDS34354.1 - 0.62 10.2 9.9 0.068 13.3 5.1 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 CDS34354.1 - 1.7 8.5 5.7 0.7 9.7 2.7 1.8 1 1 1 2 2 2 0 Septum formation initiator Peptidase_C2 PF00648.21 CDS34356.1 - 8.9e-125 415.6 0.0 1.2e-124 415.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CDS34356.1 - 1e-49 168.4 0.0 1.7e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 CDS34356.1 - 2.6e-13 48.7 0.1 3e-05 23.6 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CDS34356.1 - 1.1e-12 46.6 0.6 0.00011 21.5 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CDS34356.1 - 2.3e-09 36.9 3.7 7.6e-08 32.1 0.6 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CDS34356.1 - 5.2e-08 33.2 3.8 0.0067 16.9 0.7 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS34356.1 - 3.3e-07 29.5 1.8 0.028 13.9 0.0 3.4 3 0 0 3 3 3 2 EF hand CCDC32 PF14989.6 CDS34356.1 - 0.0028 17.7 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing 32 SCA7 PF08313.12 CDS34357.1 - 1.1e-05 25.2 1.4 1.1e-05 25.2 1.4 2.2 2 0 0 2 2 2 1 SCA7, zinc-binding domain PH PF00169.29 CDS34358.1 - 1.2e-17 64.3 0.3 5.5e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 PH domain ArfGap PF01412.18 CDS34358.1 - 1.1e-14 54.5 0.0 1.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_11 PF15413.6 CDS34358.1 - 0.17 12.3 1.9 17 5.9 0.0 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain Methyltransf_25 PF13649.6 CDS34359.1 - 1.7e-11 44.7 0.0 4.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS34359.1 - 1.9e-09 38.0 0.0 8.6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CDS34359.1 - 1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CDS34359.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDS34359.1 - 8e-06 25.5 0.1 1.4e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDS34359.1 - 8.9e-05 23.2 0.0 0.00022 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CDS34359.1 - 0.00015 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS34359.1 - 0.00065 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDS34359.1 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 CDS34359.1 - 0.0022 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 CDS34359.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CDS34359.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 CDS34359.1 - 0.047 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CDS34359.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PDCD2_C PF04194.13 CDS34360.1 - 3.7e-22 79.2 6.1 9.6e-22 77.9 0.7 2.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Actin PF00022.19 CDS34361.1 - 3e-13 49.2 0.0 3e-08 32.7 0.0 2.6 2 1 0 2 2 2 2 Actin FAR1 PF03101.15 CDS34362.1 - 0.00098 19.8 1.8 0.015 16.0 0.8 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain Homeobox_KN PF05920.11 CDS34364.1 - 1.3e-18 66.6 0.9 3.3e-18 65.3 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDS34364.1 - 1.8e-07 30.9 0.4 1.8e-07 30.9 0.4 2.3 2 0 0 2 2 2 1 Homeodomain zf-H2C2_5 PF13909.6 CDS34364.1 - 0.64 9.8 6.2 0.32 10.8 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain HTH_AsnC-type PF13404.6 CDS34364.1 - 0.7 9.8 2.1 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain zf-C2H2 PF00096.26 CDS34364.1 - 2 9.0 6.4 47 4.7 0.1 3.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cadherin PF00028.17 CDS34368.2 - 0.0017 18.7 0.0 0.031 14.7 0.0 2.1 2 0 0 2 2 2 1 Cadherin domain NGP1NT PF08153.12 CDS34368.2 - 0.06 13.5 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 NGP1NT (NUC091) domain HECT_2 PF09814.9 CDS34370.1 - 3.9e-12 45.7 0.5 1.5e-11 43.8 0.5 1.7 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 CDS34370.1 - 0.032 14.5 0.0 0.093 13.0 0.0 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Viral_NABP PF05515.11 CDS34370.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding Drf_FH3 PF06367.16 CDS34371.1 - 1.4e-20 73.7 0.2 3.5e-20 72.5 0.2 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CDS34371.1 - 1.2e-19 70.6 7.4 6.6e-11 42.1 1.2 2.6 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain EzrA PF06160.12 CDS34371.1 - 0.12 10.6 5.7 0.18 9.9 5.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fmp27_WPPW PF10359.9 CDS34371.1 - 0.33 9.7 2.0 0.55 9.0 2.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 CDS34371.1 - 3.6 7.7 8.4 12 6.0 7.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 CDS34371.1 - 3.9 4.9 10.0 5.6 4.3 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5082 PF16888.5 CDS34371.1 - 7.7 6.8 9.1 4.2 7.7 2.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Exo84_C PF16528.5 CDS34372.1 - 3.7e-18 66.1 1.0 1.4e-17 64.2 0.6 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CDS34372.1 - 2.5e-10 40.3 0.6 1.3e-09 38.0 0.3 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CDS34372.1 - 0.11 12.6 3.1 0.12 12.5 0.2 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 7tm_1 PF00001.21 CDS34373.2 - 3.1e-25 89.0 15.0 5.4e-25 88.2 15.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Amnionless PF14828.6 CDS34373.2 - 0.027 13.3 1.0 0.23 10.3 0.1 2.3 2 0 0 2 2 2 0 Amnionless UNC-79 PF14776.6 CDS34377.2 - 1.2e-131 440.1 6.1 6.1e-89 299.2 4.0 2.2 2 0 0 2 2 2 2 Cation-channel complex subunit UNC-79 Amidase PF01425.21 CDS34379.1 - 1.8e-50 172.2 0.0 2.5e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Amidase CENP-F_leu_zip PF10473.9 CDS34379.1 - 0.047 13.7 1.2 0.096 12.7 1.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Synaphin PF05835.12 CDS34380.1 - 1.3e-45 155.2 10.8 1.5e-45 155.0 10.8 1.0 1 0 0 1 1 1 1 Synaphin protein Spore_III_AF PF09581.10 CDS34380.1 - 0.041 13.9 2.1 0.055 13.5 2.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ferlin_C PF16165.5 CDS34380.1 - 0.11 12.5 4.8 0.15 12.0 4.8 1.1 1 0 0 1 1 1 0 Ferlin C-terminus DUF4226 PF10774.9 CDS34380.1 - 0.15 12.4 1.9 0.3 11.4 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) tRNA_bind_2 PF13725.6 CDS34380.1 - 0.31 10.7 3.4 0.45 10.2 3.4 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain DUF4407 PF14362.6 CDS34380.1 - 0.5 9.7 3.2 0.56 9.5 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hexokinase_2 PF03727.16 CDS34381.1 - 1e-79 267.4 0.0 1.7e-79 266.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDS34381.1 - 3e-61 206.8 0.0 4.3e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FtsK_4TM PF13491.6 CDS34381.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE TPR_12 PF13424.6 CDS34382.1 - 1.6e-12 47.6 12.3 1.9e-07 31.3 1.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34382.1 - 4.5e-06 26.4 13.0 0.0015 18.5 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS34382.1 - 7.2e-06 25.7 2.7 0.29 11.3 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS34382.1 - 1.5e-05 25.5 7.8 0.087 13.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CDS34382.1 - 0.00012 21.6 0.6 0.0013 18.2 0.5 2.3 1 1 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 CDS34382.1 - 0.00044 19.9 11.8 0.12 12.3 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS34382.1 - 0.00069 20.2 8.5 0.31 12.0 0.3 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDS34382.1 - 0.0042 17.6 5.1 0.012 16.1 1.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34382.1 - 0.013 16.0 1.9 8.7 6.9 0.0 3.4 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34382.1 - 0.018 15.2 16.8 0.3 11.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDS34382.1 - 0.038 13.9 0.6 2 8.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CDS34382.1 - 0.094 12.8 3.5 0.51 10.4 0.2 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 HEAT_2 PF13646.6 CDS34382.1 - 0.1 13.0 0.1 0.53 10.7 0.0 2.3 2 0 0 2 2 1 0 HEAT repeats TPR_6 PF13174.6 CDS34382.1 - 1.7 9.4 5.7 93 4.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS34382.1 - 2.1 8.6 10.9 4.8 7.5 0.9 4.0 2 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Hexokinase_2 PF03727.16 CDS34383.1 - 8.6e-77 257.8 0.0 1.2e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDS34383.1 - 1.3e-67 227.5 0.0 1.8e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cofilin_ADF PF00241.20 CDS34384.1 - 3.9e-16 59.0 0.0 4.5e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ints3 PF10189.9 CDS34387.2 - 3.3e-48 163.9 1.2 3.3e-48 163.9 1.2 2.0 2 0 0 2 2 2 1 Integrator complex subunit 3 DUF919 PF06034.11 CDS34387.2 - 0.13 12.1 0.9 21 5.1 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Tup_N PF08581.10 CDS34387.2 - 2.8 8.3 4.5 49 4.3 0.4 2.8 2 0 0 2 2 2 0 Tup N-terminal Pkinase_Tyr PF07714.17 CDS34388.1 - 8.4e-87 290.7 0.0 1.2e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS34388.1 - 3.4e-41 141.3 0.0 5.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CDS34388.1 - 2.1e-26 91.8 2.6 1e-14 54.4 0.1 2.4 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 CDS34388.1 - 5.1e-18 65.4 2.7 1.4e-08 35.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS34388.1 - 3.8e-16 58.9 4.4 2.9e-06 27.5 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS34388.1 - 8e-16 58.2 3.1 3e-09 37.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS34388.1 - 1.3e-15 57.0 6.1 0.00077 19.8 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CDS34388.1 - 1.2e-13 49.9 1.8 0.0071 16.8 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Haspin_kinase PF12330.8 CDS34388.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Rep_fac_C PF08542.11 CDS34389.1 - 1.3e-22 79.9 0.2 5e-22 78.1 0.1 2.0 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 CDS34389.1 - 1.5e-09 38.4 0.1 1.6e-06 28.5 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDS34389.1 - 1.8e-08 34.4 0.0 0.0048 16.7 0.0 2.8 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CDS34389.1 - 2.5e-07 30.8 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 CDS34389.1 - 2.7e-05 24.1 0.0 6.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDS34389.1 - 3.6e-05 23.6 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDS34389.1 - 0.00051 20.5 0.0 0.001 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CDS34389.1 - 0.0011 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CDS34389.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 CDS34389.1 - 0.0053 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 CDS34389.1 - 0.0093 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDS34389.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDS34389.1 - 0.035 14.4 0.0 0.096 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDS34389.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDS34389.1 - 0.06 13.0 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDS34389.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 CDS34389.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 CDS34389.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 CDS34389.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea UCH PF00443.29 CDS34390.1 - 5e-44 150.7 0.4 6.7e-44 150.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDS34390.1 - 8.2e-20 71.2 0.3 8.6e-10 39.1 0.0 2.9 2 0 0 2 2 2 2 DUSP domain UCH_1 PF13423.6 CDS34390.1 - 4.4e-13 49.5 7.3 5.2e-10 39.4 0.2 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Cadherin PF00028.17 CDS34391.2 - 3.2e-63 210.2 3.1 4.6e-16 59.0 0.0 8.6 6 2 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 CDS34391.2 - 4.1e-09 36.1 0.0 0.045 13.6 0.0 4.9 4 1 0 4 4 4 2 Cadherin-like RET_CLD1 PF17756.1 CDS34391.2 - 0.0012 19.1 0.0 7.9 6.8 0.0 3.9 3 0 0 3 3 3 2 RET Cadherin like domain 1 Cadherin_pro PF08758.11 CDS34391.2 - 0.052 13.7 0.0 0.46 10.7 0.0 2.6 4 0 0 4 4 4 0 Cadherin prodomain like EphA2_TM PF14575.6 CDS34391.2 - 0.095 13.6 0.1 0.21 12.5 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TPR_2 PF07719.17 CDS34392.1 - 2.5e-12 45.9 2.8 1.5e-05 24.7 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS34392.1 - 1.1e-10 40.8 2.8 2.6e-05 23.8 0.6 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS34392.1 - 1.9e-09 37.6 4.8 7.8e-05 22.8 1.6 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDS34392.1 - 9.5e-09 35.4 2.0 6.6e-05 23.1 0.3 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34392.1 - 9e-08 32.5 0.5 7.2e-05 23.2 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34392.1 - 2e-07 30.7 3.2 0.0028 17.8 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS34392.1 - 3.8e-06 27.3 0.2 0.13 13.1 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS34392.1 - 4.5e-06 26.3 1.7 0.12 12.4 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS34392.1 - 1.7e-05 25.3 0.0 0.013 16.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS34392.1 - 3e-05 24.0 1.4 0.15 12.2 0.1 2.5 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CDS34392.1 - 6.2e-05 23.1 3.2 0.16 12.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS34392.1 - 6.8e-05 23.3 1.1 2.7 8.8 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 CDS34392.1 - 0.00044 19.3 0.7 0.0014 17.7 0.7 1.7 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 CDS34392.1 - 0.0053 17.2 0.6 0.23 11.9 0.1 2.1 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 CDS34392.1 - 0.0065 15.7 0.5 0.35 10.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5113 PF17140.4 CDS34392.1 - 0.013 15.3 0.4 0.033 14.0 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_10 PF13374.6 CDS34392.1 - 0.06 13.2 2.0 8.8 6.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 CDS34392.1 - 0.067 13.3 1.5 17 5.6 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF357) WD40 PF00400.32 CDS34393.1 - 1.4e-43 146.0 20.1 2.5e-08 34.4 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34393.1 - 1.3e-08 35.0 0.9 0.9 9.9 0.1 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDS34393.1 - 1.1e-05 24.3 1.8 0.1 11.2 1.4 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDS34393.1 - 0.015 14.7 0.0 1 8.6 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain Pyridoxal_deC PF00282.19 CDS34394.1 - 5.1e-132 440.1 0.0 9.2e-132 439.3 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 CDS34394.1 - 0.0078 14.9 0.0 0.076 11.7 0.0 2.0 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RhoGAP PF00620.27 CDS34395.1 - 0.00034 20.5 0.1 0.00057 19.8 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF3580 PF12117.8 CDS34395.1 - 0.11 12.7 0.2 0.33 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Cadherin PF00028.17 CDS34396.1 - 1.1e-62 208.5 1.9 1.6e-14 54.1 0.0 9.0 8 1 1 9 9 9 8 Cadherin domain Cadherin_2 PF08266.12 CDS34396.1 - 5.8e-09 35.7 0.3 0.53 10.2 0.0 5.9 6 1 0 6 6 6 3 Cadherin-like GatB_N PF02934.15 CDS34397.2 - 1.5e-94 316.5 0.0 2e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain MFS_1 PF07690.16 CDS34398.1 - 2.6e-23 82.5 26.3 8.7e-16 57.8 10.3 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily C2 PF00168.30 CDS34401.1 - 3.4e-13 49.8 2.5 5.5e-06 26.6 0.9 3.6 2 2 0 2 2 2 2 C2 domain CEND1 PF15677.5 CDS34406.1 - 0.52 10.9 3.5 0.6 10.6 3.5 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 zf-C2H2 PF00096.26 CDS34407.1 - 1.5e-11 44.0 20.6 9.5e-05 22.6 3.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34407.1 - 2.5e-11 43.4 18.5 0.0026 18.4 1.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34407.1 - 3.7e-05 24.0 18.2 0.00083 19.7 0.5 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDS34407.1 - 0.00028 20.6 1.1 0.00028 20.6 1.1 4.3 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CDS34407.1 - 0.0023 18.6 8.2 1.3 9.7 3.4 3.1 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDS34407.1 - 0.0036 17.3 14.5 0.017 15.1 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-AN1 PF01428.16 CDS34407.1 - 0.0049 17.0 11.6 0.14 12.3 1.4 3.4 3 0 0 3 3 3 2 AN1-like Zinc finger zf-C2HE PF16278.5 CDS34407.1 - 0.0096 16.3 15.6 0.11 13.0 0.2 4.0 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 CDS34407.1 - 0.031 14.6 10.8 0.038 14.3 5.7 3.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 CDS34407.1 - 0.073 13.1 16.1 0.72 9.9 3.3 3.8 1 1 2 3 3 3 0 BED zinc finger Actin_micro PF17003.5 CDS34407.1 - 0.094 11.9 4.1 0.24 10.6 4.1 1.8 1 1 0 1 1 1 0 Putative actin-like family Scramblase PF03803.15 CDS34407.1 - 0.15 11.4 0.6 0.22 10.8 0.6 1.2 1 0 0 1 1 1 0 Scramblase zinc_ribbon_10 PF10058.9 CDS34407.1 - 0.71 9.6 4.6 0.19 11.5 1.2 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein LIM PF00412.22 CDS34407.1 - 0.8 10.0 11.5 1.4 9.2 0.2 3.3 1 1 1 2 2 2 0 LIM domain zf-FCS PF06467.14 CDS34407.1 - 1 9.4 7.8 6.5 6.8 0.4 3.5 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.7 CDS34407.1 - 1.4 9.3 13.0 0.48 10.8 0.7 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDS34407.1 - 2 8.3 20.5 0.43 10.4 2.9 4.0 3 1 1 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 CDS34407.1 - 2.3 8.7 13.3 2.3 8.7 1.8 3.2 3 0 0 3 3 2 0 Zinc-finger of C2H2 type DUF629 PF04780.12 CDS34407.1 - 3.5 6.0 9.6 1.9 6.9 1.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF629) RPN5_C PF18098.1 CDS34409.1 - 2.1e-16 59.7 4.3 2.1e-16 59.7 4.3 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 CDS34409.1 - 3e-11 43.8 1.7 4.2e-10 40.1 1.7 2.2 1 1 0 1 1 1 1 PCI domain Fzo_mitofusin PF04799.13 CDS34409.1 - 0.045 13.3 0.8 0.069 12.7 0.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region UEV PF05743.13 CDS34409.1 - 0.047 13.5 0.5 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 UEV domain 7tm_1 PF00001.21 CDS34412.1 - 9.5e-06 25.1 13.2 9.5e-06 25.1 13.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CDS34412.1 - 1.5e-05 24.4 21.9 0.00073 18.9 4.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Homeodomain PF00046.29 CDS34413.1 - 0.0028 17.5 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain DDA1 PF10172.9 CDS34414.1 - 0.058 13.7 0.7 0.11 12.8 0.7 1.3 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase DUF1011 PF06237.12 CDS34415.1 - 1.8e-15 57.0 14.0 5.3e-13 49.1 5.6 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1011) DUF1011 PF06237.12 CDS34416.1 - 6.6e-14 52.0 8.4 1.1e-12 48.1 2.4 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF1011) UCH PF00443.29 CDS34417.1 - 2.4e-47 161.6 0.0 7.9e-47 159.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDS34417.1 - 5.6e-13 49.2 13.7 1.3e-06 28.3 0.9 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3568 PF12092.8 CDS34417.1 - 0.1 12.7 0.6 0.23 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Transposase_1 PF01359.18 CDS34418.1 - 1.2e-11 44.2 1.3 2.3e-11 43.4 0.0 2.0 3 0 0 3 3 3 1 Transposase (partial DDE domain) Antifungal_prot PF11402.8 CDS34419.1 - 1.3 9.3 6.9 1.3 9.3 0.5 2.3 2 0 0 2 2 2 0 Antifungal protein XRN_M PF17846.1 CDS34421.2 - 1.1e-122 410.1 0.0 1.5e-118 396.6 0.0 3.1 1 1 0 1 1 1 1 Xrn1 helical domain CLIP1_ZNF PF16641.5 CDS34421.2 - 0.11 12.5 1.9 0.27 11.1 1.9 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle HAGH_C PF16123.5 CDS34423.1 - 1.2e-22 80.2 0.1 2e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDS34423.1 - 1.3e-08 35.1 1.1 0.00014 22.0 0.0 2.5 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDS34423.1 - 0.0064 16.0 0.3 0.018 14.5 0.3 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EMC3_TMCO1 PF01956.16 CDS34424.1 - 7.5e-39 133.2 0.2 9.4e-39 132.9 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TRAM1 PF08390.11 CDS34424.1 - 0.00032 20.3 0.5 0.0052 16.4 0.1 2.7 3 0 0 3 3 3 1 TRAM1-like protein DUF1666 PF07891.12 CDS34424.1 - 0.029 14.1 1.1 0.038 13.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) Vpu PF00558.19 CDS34424.1 - 0.045 13.5 0.2 0.087 12.6 0.2 1.6 1 1 0 1 1 1 0 Vpu protein FRB_dom PF08771.11 CDS34424.1 - 0.048 14.1 0.1 0.073 13.5 0.1 1.3 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain LRRC37AB_C PF14914.6 CDS34424.1 - 0.056 13.3 0.7 0.1 12.5 0.7 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Rer1 PF03248.13 CDS34424.1 - 0.058 13.1 1.6 0.11 12.3 0.1 2.0 1 1 0 2 2 2 0 Rer1 family TMPIT PF07851.13 CDS34424.1 - 0.08 12.2 3.6 3.6 6.8 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein Nucleoside_tran PF01733.18 CDS34424.1 - 0.093 12.1 2.6 0.23 10.8 1.0 1.8 1 1 1 2 2 2 0 Nucleoside transporter LapA_dom PF06305.11 CDS34424.1 - 2.2 8.2 4.7 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SieB PF14163.6 CDS34424.1 - 2.9 7.4 7.9 17 4.9 4.5 2.8 2 1 0 2 2 2 0 Super-infection exclusion protein B RabGAP-TBC PF00566.18 CDS34425.1 - 3e-53 180.7 0.2 5.4e-53 179.8 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GAS PF13851.6 CDS34425.1 - 0.0091 15.4 4.2 0.0091 15.4 4.2 3.5 3 0 0 3 3 3 2 Growth-arrest specific micro-tubule binding LPP PF04728.13 CDS34425.1 - 0.082 13.3 3.9 3.4 8.1 0.2 3.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper MbeD_MobD PF04899.12 CDS34425.1 - 4.8 7.4 7.4 2.4 8.3 0.2 3.7 3 1 0 3 3 3 0 MbeD/MobD like IMD PF08397.11 CDS34426.1 - 5.9e-47 159.9 1.3 1.2e-35 122.9 0.1 2.5 3 0 0 3 3 3 2 IRSp53/MIM homology domain TACC_C PF05010.14 CDS34426.1 - 0.013 15.3 3.2 0.016 15.0 0.6 2.4 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GDP_Man_Dehyd PF16363.5 CDS34427.1 - 2.6e-155 516.8 0.0 3e-155 516.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDS34427.1 - 1.8e-73 247.0 0.2 4.7e-73 245.6 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDS34427.1 - 2.3e-07 30.2 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDS34427.1 - 0.00017 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDS34427.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.8 1 1 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 CDS34427.1 - 0.058 13.3 0.0 0.26 11.2 0.0 2.3 2 1 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 CDS34427.1 - 0.063 12.7 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase RRM_1 PF00076.22 CDS34428.1 - 9.2e-57 188.8 0.0 9.5e-19 67.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS34428.1 - 7.2e-10 38.5 0.0 0.00037 20.1 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDS34428.1 - 0.0037 17.1 0.1 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif SapB_1 PF05184.15 CDS34428.1 - 0.19 11.8 0.0 0.61 10.2 0.0 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 1 BTB PF00651.31 CDS34429.1 - 1.4e-24 86.4 0.3 3.3e-24 85.3 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CDS34429.1 - 6.1e-23 80.9 0.5 1.1e-22 80.0 0.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CDS34429.1 - 1.1e-22 79.3 8.3 1.8e-08 33.8 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDS34429.1 - 4.1e-14 52.3 8.8 5.4e-07 29.5 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CDS34429.1 - 1.2e-10 41.3 9.5 0.00019 21.6 0.0 5.9 5 2 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CDS34429.1 - 3.6e-10 39.9 1.0 5.5e-05 23.3 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CDS34429.1 - 2.9e-07 30.3 6.9 0.0017 18.3 0.3 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CDS34429.1 - 1e-06 28.5 2.4 0.32 11.1 0.3 4.0 3 0 0 3 3 3 3 Kelch motif PQQ_3 PF13570.6 CDS34429.1 - 0.0067 16.9 0.1 8.3 7.0 0.0 3.5 3 0 0 3 3 3 1 PQQ-like domain Spectrin PF00435.21 CDS34430.2 - 7.4e-45 151.8 184.0 5.5e-11 42.9 2.5 28.5 26 3 3 29 29 29 14 Spectrin repeat CH PF00307.31 CDS34430.2 - 4.5e-35 120.1 0.7 1.6e-16 60.5 0.1 4.5 4 0 0 4 4 3 2 Calponin homology (CH) domain GAS2 PF02187.17 CDS34430.2 - 3.1e-28 97.7 0.1 8.7e-28 96.2 0.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Plectin PF00681.20 CDS34430.2 - 5.6e-10 38.9 0.0 0.013 15.3 0.0 7.1 5 3 3 8 8 8 2 Plectin repeat EF-hand_7 PF13499.6 CDS34430.2 - 9.2e-09 35.6 0.1 3.9e-07 30.4 0.1 3.8 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 CDS34430.2 - 5e-06 26.3 0.0 0.14 12.0 0.0 3.4 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 CDS34430.2 - 0.00021 20.9 0.2 0.016 15.1 0.2 3.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDS34430.2 - 0.00076 18.9 0.1 0.007 15.8 0.1 2.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CDS34430.2 - 0.00088 18.7 0.1 0.0044 16.4 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CDS34430.2 - 0.0089 15.9 1.2 0.29 11.0 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair SH3_10 PF17902.1 CDS34430.2 - 0.021 14.9 0.0 0.076 13.1 0.0 2.0 1 0 0 1 1 1 0 SH3 domain DUF2935 PF11155.8 CDS34430.2 - 0.021 15.1 18.0 0.33 11.3 0.3 7.5 7 0 0 7 7 5 0 Domain of unknown function (DUF2935) FNIP PF05725.12 CDS34430.2 - 0.092 12.9 0.8 18 5.6 0.1 3.1 2 0 0 2 2 2 0 FNIP Repeat Mob1_phocein PF03637.17 CDS34431.1 - 1.2e-20 74.2 0.0 1.9e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family TPR_8 PF13181.6 CDS34433.1 - 0.45 10.9 1.5 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DCB PF16213.5 CDS34440.2 - 1.5e-43 148.5 5.3 1.5e-43 148.5 5.3 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CDS34440.2 - 4.6e-33 114.4 0.1 1.8e-32 112.4 0.1 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec23_trunk PF04811.15 CDS34441.2 - 4.7e-56 190.1 0.0 8.3e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDS34441.2 - 6.7e-20 71.6 0.0 1.4e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDS34441.2 - 5.1e-19 68.0 0.1 3.1e-18 65.5 0.0 2.3 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDS34441.2 - 0.00015 21.7 0.0 0.00045 20.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDS34441.2 - 0.0082 16.0 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CDS34441.2 - 0.025 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ATP-grasp_2 PF08442.10 CDS34443.2 - 1.4e-51 175.0 0.2 2.3e-51 174.2 0.0 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDS34443.2 - 2.2e-19 69.8 0.0 4.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CDS34443.2 - 0.00099 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Pkinase PF00069.25 CDS34445.2 - 7.5e-33 114.0 0.0 8.3e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34445.2 - 1.2e-31 110.0 0.0 1.9e-24 86.4 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDS34445.2 - 0.002 16.9 0.0 0.007 15.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase NARP1 PF12569.8 CDS34446.2 - 1.6e-157 525.5 17.4 1.3e-156 522.5 13.8 2.5 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 CDS34446.2 - 1.3e-10 41.2 0.2 1.6 9.7 0.0 8.2 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34446.2 - 2.6e-09 37.4 7.3 0.32 11.5 0.0 7.0 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS34446.2 - 1.9e-07 31.0 1.1 0.15 12.5 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34446.2 - 3.9e-07 29.8 8.9 0.91 9.9 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34446.2 - 3.1e-06 26.9 12.4 1.1 9.5 0.2 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS34446.2 - 1.3e-05 24.8 13.3 0.11 12.4 0.1 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS34446.2 - 6.2e-05 23.6 0.3 3.4 8.4 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS34446.2 - 0.0013 19.0 12.5 12 6.2 0.0 6.9 4 3 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDS34446.2 - 0.0013 19.0 6.6 14 6.1 0.0 6.2 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDS34446.2 - 0.0027 17.3 3.7 0.028 14.1 0.2 3.9 3 0 0 3 3 3 1 TPR repeat TPR_4 PF07721.14 CDS34446.2 - 0.022 15.4 0.0 12 6.9 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS34446.2 - 0.075 13.1 3.4 53 4.0 0.1 4.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CDS34446.2 - 0.087 12.7 7.8 28 4.7 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DRY_EERY PF09750.9 CDS34449.1 - 1.5e-27 96.5 0.3 1.5e-27 96.5 0.3 3.6 3 0 0 3 3 3 1 Alternative splicing regulator Surp PF01805.20 CDS34449.1 - 5.6e-27 93.5 3.1 3.1e-14 52.7 0.2 3.0 3 0 0 3 3 3 2 Surp module CEP44 PF15007.6 CDS34450.2 - 6.1e-31 107.2 0.3 1.1e-30 106.4 0.3 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 MitMem_reg PF13012.6 CDS34450.2 - 0.019 15.4 2.5 0.068 13.6 0.5 2.4 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function FlaC_arch PF05377.11 CDS34450.2 - 0.78 10.2 6.3 0.44 11.0 0.7 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Fic PF02661.18 CDS34451.1 - 4.1e-25 88.5 0.0 1.3e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.6 CDS34451.1 - 0.00018 21.1 0.1 0.0029 17.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 CDS34451.1 - 0.0099 16.2 0.0 0.47 10.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34451.1 - 0.095 12.9 0.0 37 4.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4172 PF13776.6 CDS34451.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) SDF PF00375.18 CDS34452.1 - 5.1e-10 38.9 0.4 5.7e-10 38.8 0.4 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 CDS34454.1 - 1.4e-71 241.6 33.1 1.8e-71 241.3 33.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Tetraspanin PF00335.20 CDS34454.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.6 2 0 0 2 2 2 0 Tetraspanin family SDF PF00375.18 CDS34455.1 - 3.9e-70 236.8 32.9 3.9e-70 236.8 32.9 1.4 2 0 0 2 2 2 1 Sodium:dicarboxylate symporter family Tetraspanin PF00335.20 CDS34455.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetraspanin family SDF PF00375.18 CDS34456.2 - 1.2e-69 235.3 32.3 8.6e-54 183.0 16.7 2.0 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family Orf78 PF06024.12 CDS34456.2 - 1.7 9.0 4.3 0.85 10.0 0.4 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Fic PF02661.18 CDS34457.1 - 4.1e-25 88.5 0.0 1.3e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.6 CDS34457.1 - 0.00018 21.1 0.1 0.0029 17.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 CDS34457.1 - 0.01 16.2 0.0 0.48 10.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34457.1 - 0.09 12.9 0.0 37 4.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4172 PF13776.6 CDS34457.1 - 0.13 12.6 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) DRY_EERY PF09750.9 CDS34459.1 - 6.1e-25 88.1 0.0 7.3e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Alternative splicing regulator DUF89 PF01937.19 CDS34460.1 - 1.5e-76 257.6 0.0 1.8e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CBP_BcsR PF10945.8 CDS34460.1 - 0.05 13.1 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR NARP1 PF12569.8 CDS34462.2 - 1.1e-151 506.3 15.3 1.5e-150 502.5 12.6 2.4 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 CDS34462.2 - 1.7e-11 43.9 0.1 1.6 9.8 0.0 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34462.2 - 1.5e-08 35.1 5.3 0.13 12.8 0.1 6.7 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDS34462.2 - 9.9e-07 28.7 0.4 0.15 12.5 0.0 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34462.2 - 1.5e-06 27.9 9.3 0.89 9.9 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDS34462.2 - 3.7e-06 26.6 12.3 1.1 9.5 0.2 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDS34462.2 - 3.6e-05 23.4 13.8 0.1 12.5 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDS34462.2 - 0.00011 22.8 0.7 3.3 8.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDS34462.2 - 0.00083 19.6 5.3 14 6.1 0.0 6.0 6 2 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS34462.2 - 0.0015 18.7 9.0 13 6.1 0.0 6.8 4 3 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDS34462.2 - 0.0036 16.9 3.8 0.027 14.1 0.2 3.8 3 0 0 3 3 3 1 TPR repeat TPR_4 PF07721.14 CDS34462.2 - 0.019 15.5 0.0 11 6.9 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDS34462.2 - 0.079 13.0 3.4 51 4.0 0.1 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CDS34462.2 - 0.2 11.6 8.1 28 4.8 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PcfK PF14058.6 CDS34462.2 - 1.2 9.4 10.9 24 5.2 0.1 4.3 4 0 0 4 4 4 0 PcfK-like protein N_BRCA1_IG PF16158.5 CDS34463.1 - 2.2e-07 31.5 0.0 4.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ATP-grasp_2 PF08442.10 CDS34466.2 - 1.4e-51 175.0 0.2 2.3e-51 174.2 0.0 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDS34466.2 - 2.2e-19 69.8 0.0 4.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CDS34466.2 - 0.00099 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Glyco_tran_28_C PF04101.16 CDS34467.1 - 3.5e-20 72.6 0.0 4.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Sec23_trunk PF04811.15 CDS34468.1 - 9.5e-56 189.1 0.0 1.8e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDS34468.1 - 7.8e-20 71.4 0.0 2.4e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDS34468.1 - 7.8e-19 67.4 0.1 5.6e-18 64.7 0.0 2.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CDS34468.1 - 3.1e-15 55.9 2.8 9.1e-15 54.4 2.8 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDS34468.1 - 0.0087 15.9 0.1 0.057 13.3 0.0 2.5 3 0 0 3 3 3 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CDS34468.1 - 0.026 13.9 0.0 0.09 12.2 0.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Calreticulin PF00262.18 CDS34470.1 - 1.3e-80 271.0 9.5 2.1e-56 191.4 1.4 2.1 1 1 1 2 2 2 2 Calreticulin family rRNA_proc-arch PF13234.6 CDS34471.2 - 2.7e-63 214.4 0.3 3.9e-63 213.9 0.3 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CDS34471.2 - 2.5e-52 176.9 0.2 6.8e-52 175.4 0.2 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain GCP_N_terminal PF17681.1 CDS34472.2 - 2.3e-31 109.6 0.1 1e-30 107.4 0.1 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDS34472.2 - 2.4e-30 106.1 9.5 1.4e-29 103.5 8.4 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal IRK PF01007.20 CDS34472.2 - 0.024 14.5 2.1 1.1 9.1 0.3 2.6 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF3535 PF12054.8 CDS34472.2 - 0.11 11.7 0.8 0.48 9.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) RPN7 PF10602.9 CDS34472.2 - 0.12 12.0 0.6 0.21 11.3 0.6 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 NPV_P10 PF05531.12 CDS34475.2 - 0.0023 18.4 10.0 0.025 15.0 0.8 3.4 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 CDS34475.2 - 0.0083 16.5 1.9 0.0083 16.5 1.9 4.7 2 2 2 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 CDS34475.2 - 0.1 12.7 23.1 0.27 11.3 3.0 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) RUN PF02759.19 CDS34475.2 - 0.21 11.5 11.1 2.3 8.2 0.0 4.5 3 2 0 3 3 2 0 RUN domain DUF812 PF05667.11 CDS34475.2 - 0.57 9.0 47.6 0.2 10.5 44.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF812) PI_PP_I PF18363.1 CDS34475.2 - 1.8 8.8 5.5 4 7.7 1.3 2.8 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF4201 PF13870.6 CDS34475.2 - 4.1 7.1 43.8 0.087 12.6 22.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 CDS34475.2 - 4.3 7.5 65.9 1.7 8.8 10.8 4.8 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CDS34475.2 - 6.7 5.9 40.9 0.013 14.8 15.9 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 CDS34475.2 - 7 4.0 47.3 9.6 3.6 47.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 CDS34475.2 - 7.9 6.9 33.8 0.11 12.8 3.0 4.4 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Carb_anhydrase PF00194.21 CDS34476.2 - 3.5e-72 243.0 0.1 4.3e-72 242.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GST_C PF00043.25 CDS34477.1 - 2.2e-13 50.2 0.0 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDS34477.1 - 4.2e-12 46.1 0.0 6.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Herpes_UL7 PF01677.16 CDS34477.1 - 0.00069 19.4 0.1 1.2 8.8 0.0 2.4 2 1 0 2 2 2 2 Herpesvirus UL7 like GST_C_2 PF13410.6 CDS34477.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TEP1_N PF05386.11 CDS34477.1 - 0.38 10.4 1.7 4 7.1 0.0 2.7 3 0 0 3 3 3 0 TEP1 N-terminal domain GST_C_3 PF14497.6 CDS34478.2 - 2.1e-24 85.6 0.6 2.5e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDS34478.2 - 8.8e-24 83.6 0.1 1.4e-12 47.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDS34478.2 - 8.4e-11 42.1 0.0 2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDS34478.2 - 1.6e-08 34.5 0.0 0.0085 16.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDS34478.2 - 1.7e-05 24.5 0.7 0.025 14.4 0.1 2.9 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDS34478.2 - 0.0019 18.6 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sod_Fe_C PF02777.18 CDS34478.2 - 0.042 14.0 0.1 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain DUF5454 PF17535.2 CDS34478.2 - 0.075 12.4 1.5 0.55 9.6 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5454) Carb_anhydrase PF00194.21 CDS34479.2 - 3.2e-64 216.9 0.7 4.2e-64 216.5 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MutS_V PF00488.21 CDS34481.2 - 7.1e-71 238.1 0.1 1.3e-70 237.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDS34481.2 - 2.2e-34 119.3 0.4 8.6e-34 117.4 0.4 2.1 1 0 0 1 1 1 1 MutS domain III GCP_C_terminal PF04130.13 CDS34481.2 - 6.4e-29 101.4 8.3 1.7e-28 100.0 8.3 1.8 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal MutS_IV PF05190.18 CDS34481.2 - 1.4e-12 47.8 0.2 4.6e-12 46.1 0.1 2.1 2 0 0 2 2 2 1 MutS family domain IV GCP_N_terminal PF17681.1 CDS34481.2 - 1.1e-06 28.5 0.1 5.5e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal MutS_II PF05188.17 CDS34481.2 - 1.9e-06 28.2 0.0 6e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 CDS34481.2 - 0.00079 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I Calreticulin PF00262.18 CDS34483.1 - 1.3e-80 271.0 9.5 2.1e-56 191.4 1.4 2.1 1 1 1 2 2 2 2 Calreticulin family Calreticulin PF00262.18 CDS34484.1 - 2.1e-79 267.1 16.5 3.7e-55 187.3 4.9 2.2 1 1 1 2 2 2 2 Calreticulin family PAP2 PF01569.21 CDS34493.1 - 9.2e-24 83.8 2.7 1.1e-23 83.5 2.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 CDS34493.1 - 6.7e-05 23.3 2.2 6.7e-05 23.3 2.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Sugar_tr PF00083.24 CDS34493.1 - 0.0036 16.2 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Polysacc_synt_C PF14667.6 CDS34493.1 - 0.041 14.0 0.4 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PAP2_3 PF14378.6 CDS34493.1 - 0.27 10.9 3.9 0.72 9.5 3.9 1.7 1 1 0 1 1 1 0 PAP2 superfamily PB1 PF00564.24 CDS34494.1 - 5.1e-10 39.2 0.9 7.7e-10 38.6 0.9 1.3 1 0 0 1 1 1 1 PB1 domain HSD3 PF15244.6 CDS34494.1 - 0.078 12.5 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PNP_UDP_1 PF01048.20 CDS34495.1 - 7.2e-49 166.2 0.1 8.1e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 CDS34496.2 - 4.6e-47 160.2 1.3 5.2e-47 160.1 1.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Mut7-C PF01927.16 CDS34496.2 - 0.12 12.5 0.2 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 Mut7-C RNAse domain PNP_UDP_1 PF01048.20 CDS34497.1 - 0.003 16.8 0.1 0.0031 16.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mntp PF02659.15 CDS34497.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative manganese efflux pump Zn_ribbon_SprT PF17283.2 CDS34499.1 - 0.62 10.0 3.9 0.3 11.0 1.6 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain PNP_UDP_1 PF01048.20 CDS34500.1 - 3.6e-48 163.8 1.2 4.1e-48 163.7 1.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Mut7-C PF01927.16 CDS34500.1 - 0.13 12.4 0.1 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Mut7-C RNAse domain PNP_UDP_1 PF01048.20 CDS34501.1 - 7.2e-49 166.2 0.1 8.1e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PB1 PF00564.24 CDS34502.2 - 5.3e-10 39.1 0.9 8.1e-10 38.5 0.9 1.3 1 0 0 1 1 1 1 PB1 domain HSD3 PF15244.6 CDS34502.2 - 0.082 12.4 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PAP2 PF01569.21 CDS34503.1 - 8.4e-11 41.8 0.8 1e-10 41.5 0.8 1.1 1 0 0 1 1 1 1 PAP2 superfamily Sugar_tr PF00083.24 CDS34503.1 - 0.0023 16.9 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PAP2_C PF14360.6 CDS34503.1 - 0.003 18.1 0.4 0.004 17.7 0.4 1.2 1 0 0 1 1 1 1 PAP2 superfamily C-terminal FERM_M PF00373.18 CDS34510.1 - 2.5e-30 105.3 0.0 4.4e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 FERM central domain PH PF00169.29 CDS34510.1 - 2.1e-06 28.2 0.0 4.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Kindlin_2_N PF18124.1 CDS34512.1 - 1.4e-28 98.9 1.1 2e-28 98.4 1.1 1.2 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain STAR_dimer PF16544.5 CDS34514.2 - 1.5e-16 59.7 0.5 4.2e-16 58.2 0.5 1.8 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CDS34514.2 - 0.00016 21.5 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 KH domain STOP PF05217.12 CDS34514.2 - 0.3 11.4 1.3 0.81 10.0 1.3 1.7 1 0 0 1 1 1 0 STOP protein DUF1700 PF08006.11 CDS34516.1 - 1.7 8.1 8.8 2 7.9 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TAF1_subA PF14929.6 CDS34517.1 - 5.4e-08 32.7 5.1 2.3e-05 24.0 5.1 2.9 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A NARG2_C PF10505.9 CDS34518.1 - 1.2e-11 44.5 0.0 6.8e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus DUF1754 PF08555.10 CDS34518.1 - 0.0023 18.7 13.7 0.012 16.4 4.8 2.8 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) UAA PF08449.11 CDS34520.2 - 1.1e-38 133.1 11.3 2.7e-38 131.9 11.3 1.6 1 0 0 1 1 1 1 UAA transporter family PCI PF01399.27 CDS34520.2 - 1e-17 64.6 0.3 2.4e-17 63.4 0.3 1.7 1 0 0 1 1 1 1 PCI domain CRT-like PF08627.10 CDS34520.2 - 0.00082 18.4 10.1 0.37 9.7 2.0 3.6 4 0 0 4 4 4 3 CRT-like, chloroquine-resistance transporter-like Wzy_C PF04932.15 CDS34520.2 - 0.0018 17.9 0.3 0.52 9.9 0.3 2.6 1 1 0 1 1 1 1 O-Antigen ligase TPT PF03151.16 CDS34520.2 - 0.0036 16.7 9.3 0.036 13.4 3.9 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 CDS34520.2 - 0.03 14.5 24.4 0.38 10.9 15.1 2.7 3 0 0 3 3 3 0 EamA-like transporter family Aldo_ket_red PF00248.21 CDS34521.2 - 1.7e-48 165.4 0.0 4.1e-47 160.8 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydr_116N PF12215.8 CDS34523.1 - 2e-09 37.4 0.1 3.8e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ribonuc_red_lgC PF02867.15 CDS34526.1 - 3.7e-181 603.2 0.0 4.6e-181 602.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDS34526.1 - 2.9e-23 81.7 0.0 6.3e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDS34526.1 - 1e-10 42.0 0.0 3.1e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 CDS34526.1 - 0.042 14.1 0.7 0.1 12.8 0.7 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein SART-1 PF03343.13 CDS34527.2 - 3.1e-130 435.7 41.2 3.1e-130 435.7 41.2 1.9 2 0 0 2 2 2 1 SART-1 family LcrG PF07216.12 CDS34527.2 - 0.0066 16.3 0.7 0.058 13.3 0.1 2.8 2 0 0 2 2 2 1 LcrG protein DUF4011 PF13195.6 CDS34527.2 - 0.041 13.8 5.1 0.14 12.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4011) 7tm_2 PF00002.24 CDS34528.1 - 3.8e-05 23.1 18.1 0.0014 17.9 10.2 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 CDS34529.1 - 3.8e-05 23.1 18.1 0.0014 17.9 10.2 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) SART-1 PF03343.13 CDS34530.1 - 3.1e-130 435.7 41.2 3.1e-130 435.7 41.2 1.9 2 0 0 2 2 2 1 SART-1 family LcrG PF07216.12 CDS34530.1 - 0.0066 16.3 0.7 0.058 13.3 0.1 2.8 2 0 0 2 2 2 1 LcrG protein DUF4011 PF13195.6 CDS34530.1 - 0.041 13.8 5.1 0.14 12.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4011) Ribonuc_red_lgC PF02867.15 CDS34531.1 - 3.7e-181 603.2 0.0 4.6e-181 602.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDS34531.1 - 2.9e-23 81.7 0.0 6.3e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDS34531.1 - 1e-10 42.0 0.0 3.1e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 CDS34531.1 - 0.042 14.1 0.7 0.1 12.8 0.7 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein MutS_I PF01624.20 CDS34532.2 - 2e-56 189.1 4.5 6.2e-18 65.1 0.1 4.4 2 2 2 4 4 4 4 MutS domain I MutS_III PF05192.18 CDS34532.2 - 5.6e-26 91.9 0.0 1.5e-25 90.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CDS34532.2 - 2.2e-08 34.3 0.0 6.2e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CDS34532.2 - 1.4e-05 25.4 0.0 0.00035 20.9 0.0 2.9 2 0 0 2 2 2 1 MutS domain II DUF4860 PF16152.5 CDS34532.2 - 0.23 11.4 0.7 30 4.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4860) BESS PF02944.20 CDS34532.2 - 1.9 8.4 4.2 0.55 10.1 0.1 2.4 3 0 0 3 3 3 0 BESS motif DUF608 PF04685.13 CDS34533.1 - 9.3e-127 423.1 4.3 1.1e-126 422.8 4.3 1.1 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 CDS34534.2 - 2.4e-74 250.7 0.0 6.1e-74 249.3 0.0 1.7 1 1 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term MRP-S22 PF10245.9 CDS34535.1 - 9.7e-83 277.6 0.4 1.2e-82 277.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 DSPc PF00782.20 CDS34536.1 - 2.8e-20 72.5 0.0 3.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDS34536.1 - 8.5e-05 22.7 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CDS34536.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RNA_pol_Rpb2_4 PF04566.13 CDS34536.1 - 0.11 12.8 0.2 1.3 9.4 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 Mannosyl_trans PF05007.13 CDS34537.2 - 5e-53 180.6 20.5 1.6e-52 178.9 20.5 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CDS34537.2 - 9.3e-11 41.4 5.0 9.3e-11 41.4 5.0 1.9 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CDS34537.2 - 2e-05 24.4 7.7 2e-05 24.4 7.7 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 87 CoA_binding_3 PF13727.6 CDS34537.2 - 0.0043 17.1 1.2 0.0043 17.1 1.2 2.3 3 0 0 3 3 3 1 CoA-binding domain Aldo_ket_red PF00248.21 CDS34538.2 - 7.5e-31 107.4 0.0 1.6e-29 103.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UAA PF08449.11 CDS34539.2 - 7.4e-34 117.3 12.9 1.7e-33 116.1 12.9 1.6 1 0 0 1 1 1 1 UAA transporter family PCI PF01399.27 CDS34539.2 - 1.3e-17 64.2 0.3 3e-17 63.0 0.3 1.7 1 0 0 1 1 1 1 PCI domain CRT-like PF08627.10 CDS34539.2 - 0.00034 19.7 11.8 0.2 10.6 0.5 3.5 3 0 0 3 3 3 3 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 CDS34539.2 - 0.0012 18.3 9.3 0.053 12.9 4.2 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family Wzy_C PF04932.15 CDS34539.2 - 0.0018 17.9 0.3 0.89 9.2 0.0 2.5 1 1 1 2 2 2 2 O-Antigen ligase EamA PF00892.20 CDS34539.2 - 0.0029 17.8 23.3 0.24 11.6 1.1 2.7 2 0 0 2 2 2 2 EamA-like transporter family DUF948 PF06103.11 CDS34545.1 - 0.00052 20.2 5.9 0.12 12.7 1.5 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) DUF885 PF05960.11 CDS34545.1 - 0.13 11.9 0.2 8.3 5.9 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) YkyA PF10368.9 CDS34545.1 - 0.48 10.1 5.5 1.9 8.1 1.7 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Sulfatase PF00884.23 CDS34545.1 - 0.79 9.1 12.4 1.2 8.5 1.1 3.2 1 1 1 3 3 3 0 Sulfatase YtxH PF12732.7 CDS34545.1 - 5.2 7.7 10.1 1.1 9.8 2.2 2.4 2 0 0 2 2 2 0 YtxH-like protein DUF2070 PF09843.9 CDS34555.1 - 0.47 8.7 5.5 0.5 8.6 5.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) bZIP_2 PF07716.15 CDS34557.2 - 0.0065 16.5 8.8 0.01 15.9 8.8 1.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDS34557.2 - 0.39 10.9 6.9 0.65 10.1 6.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor ArfGap PF01412.18 CDS34559.2 - 5.7e-61 203.8 5.8 5.7e-31 107.0 0.6 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf DUF19 PF01579.18 CDS34559.2 - 0.0042 16.9 0.1 4.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF19) DUF3973 PF13119.6 CDS34559.2 - 0.016 15.3 3.5 3.7 7.7 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) A_deaminase_N PF08451.11 CDS34559.2 - 0.027 14.8 0.6 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal SAICAR_synt PF01259.18 CDS34559.2 - 0.057 13.0 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 SAICAR synthetase DUF4899 PF16240.5 CDS34559.2 - 0.061 12.5 0.1 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) KapB PF08810.10 CDS34559.2 - 0.092 12.9 2.9 1.5 9.1 0.0 3.4 4 0 0 4 4 4 0 Kinase associated protein B DUF1081 PF06448.11 CDS34559.2 - 0.33 11.4 5.7 13 6.2 0.0 3.5 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1081) A2L_zn_ribbon PF08792.10 CDS34559.2 - 1.1 9.0 8.9 26 4.7 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain UPAR_LY6_2 PF16975.5 CDS34562.1 - 2.6e-05 24.4 5.0 3.2e-05 24.1 5.0 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 KapB PF08810.10 CDS34569.2 - 0.15 12.3 0.5 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Kinase associated protein B C2-set_2 PF08205.12 CDS34573.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain SurE PF01975.17 CDS34578.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Survival protein SurE EF-hand_7 PF13499.6 CDS34584.1 - 1.3e-22 80.0 3.1 7.9e-16 58.3 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS34584.1 - 9.5e-21 71.8 10.3 5.1e-07 28.8 0.8 4.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDS34584.1 - 2.9e-20 70.4 1.4 8.7e-06 25.3 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDS34584.1 - 1.2e-17 63.4 3.4 7.2e-08 32.2 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDS34584.1 - 1.5e-14 52.7 6.7 5.6e-05 22.4 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CDS34584.1 - 4.6e-05 23.3 1.1 0.63 10.0 0.1 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDS34584.1 - 0.00061 20.1 0.9 0.38 11.1 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region MecA_N PF05223.11 CDS34584.1 - 0.02 15.2 0.0 0.2 11.9 0.0 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain EF-hand_9 PF14658.6 CDS34584.1 - 0.022 15.1 0.0 0.072 13.4 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 CDS34584.1 - 0.11 12.4 1.0 31 4.4 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein EF-hand_10 PF14788.6 CDS34584.1 - 0.25 11.2 1.7 18 5.3 0.2 3.1 3 1 0 3 3 3 0 EF hand C2 PF00168.30 CDS34585.1 - 1.2e-54 182.9 0.0 6.1e-28 97.1 0.0 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CDS34585.1 - 3.1e-05 23.6 0.0 0.24 10.9 0.0 2.6 3 0 0 3 3 3 2 CEP76 C2 domain Glycophorin_A PF01102.18 CDS34585.1 - 0.0093 16.2 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A FAM176 PF14851.6 CDS34585.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 FAM176 family FeoB_C PF07664.12 CDS34585.1 - 0.24 11.1 2.4 9.8 6.0 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus Rrn6 PF10214.9 CDS34593.1 - 0.23 9.9 2.9 0.23 9.9 2.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Circo_capsid PF02443.15 CDS34593.1 - 5 6.6 10.8 5 6.6 10.8 1.1 1 0 0 1 1 1 0 Circovirus capsid protein zf-C2H2_11 PF16622.5 CDS34595.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type IMS PF00817.20 CDS34599.1 - 6.4e-38 130.1 0.0 2.6e-37 128.1 0.0 2.1 2 1 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CDS34599.1 - 1.2e-18 67.9 0.2 3.4e-18 66.4 0.2 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDS34599.1 - 2.9e-08 33.6 0.0 8.1e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF4821 PF16092.5 CDS34600.2 - 1.2e-39 136.6 8.2 7.6e-31 107.7 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) DUF4821 PF16092.5 CDS34601.2 - 7e-23 81.6 0.7 1e-22 81.0 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4821) PPTA PF01239.22 CDS34603.1 - 9.8e-36 120.5 18.7 1.7e-09 37.1 0.3 6.3 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 CDS34603.1 - 4.1e-08 33.4 7.9 0.0012 19.1 0.2 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDS34603.1 - 8.1e-07 28.7 2.6 5.2e-05 22.9 1.0 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CDS34603.1 - 0.00012 21.7 1.8 0.00021 20.8 0.3 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CDS34603.1 - 0.041 13.9 5.5 3.1 8.1 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CDS34603.1 - 0.23 12.1 5.7 1.1e+02 4.0 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LsmAD PF06741.13 CDS34604.1 - 3.2e-15 56.4 0.3 7.3e-15 55.3 0.3 1.7 1 0 0 1 1 1 1 LsmAD domain EzrA PF06160.12 CDS34604.1 - 0.095 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 CDS34608.2 - 0.23 10.3 12.1 0.36 9.7 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDS34608.2 - 0.28 10.5 4.3 0.4 10.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glu_syn_central PF04898.14 CDS34608.2 - 0.33 10.4 2.6 0.55 9.7 2.6 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain MCU PF04678.13 CDS34608.2 - 0.37 10.9 4.0 0.62 10.1 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HMMR_C PF15908.5 CDS34608.2 - 0.67 10.2 10.1 1.3 9.3 9.7 1.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Adaptin_binding PF10199.9 CDS34608.2 - 1.6 9.3 8.1 8.2 7.1 8.1 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DMPK_coil PF08826.10 CDS34608.2 - 2.2 8.5 15.3 0.16 12.1 7.0 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF3450 PF11932.8 CDS34608.2 - 2.4 7.4 12.7 6.7 5.9 12.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 CDS34608.2 - 2.8 8.4 12.6 2.2 8.7 9.2 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 CDS34608.2 - 3 7.9 17.9 0.6 10.1 5.4 2.6 1 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 CDS34608.2 - 3.3 7.5 12.6 7.5 6.3 1.1 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 CDS34608.2 - 5 4.9 7.9 6.4 4.5 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CDS34608.2 - 7.1 6.7 7.0 14 5.7 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ACCA PF03255.14 CDS34608.2 - 8.7 6.2 8.2 7.2 6.5 4.8 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit UDPG_MGDP_dh_N PF03721.14 CDS34609.1 - 5.8e-60 202.1 0.1 1.2e-59 201.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CDS34609.1 - 5.8e-30 103.4 0.0 1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CDS34609.1 - 4.1e-29 101.1 0.8 9.3e-23 80.7 0.1 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CDS34609.1 - 0.0023 18.1 0.0 0.038 14.2 0.0 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PIP5K PF01504.18 CDS34610.2 - 2.3e-91 305.8 0.0 3.6e-91 305.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.18 CDS34613.2 - 3.4e-91 305.3 0.0 5.4e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UDPG_MGDP_dh_N PF03721.14 CDS34614.2 - 5.8e-60 202.1 0.1 1.2e-59 201.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CDS34614.2 - 5.8e-30 103.4 0.0 1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CDS34614.2 - 4.1e-29 101.1 0.8 9.3e-23 80.7 0.1 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CDS34614.2 - 0.0023 18.1 0.0 0.038 14.2 0.0 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Spc7 PF08317.11 CDS34615.2 - 0.23 10.3 12.1 0.36 9.7 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDS34615.2 - 0.28 10.5 4.3 0.4 10.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glu_syn_central PF04898.14 CDS34615.2 - 0.33 10.4 2.6 0.55 9.7 2.6 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain MCU PF04678.13 CDS34615.2 - 0.37 10.9 4.0 0.62 10.1 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HMMR_C PF15908.5 CDS34615.2 - 0.66 10.2 10.1 1.3 9.3 9.7 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Adaptin_binding PF10199.9 CDS34615.2 - 1.6 9.3 8.1 8.2 7.1 8.1 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DMPK_coil PF08826.10 CDS34615.2 - 2.2 8.5 15.3 0.16 12.1 7.0 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF3450 PF11932.8 CDS34615.2 - 2.4 7.4 12.7 6.7 5.9 12.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.12 CDS34615.2 - 2.8 8.4 12.6 2.2 8.7 9.2 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 CDS34615.2 - 3 7.9 17.9 0.6 10.1 5.4 2.6 1 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 CDS34615.2 - 3.3 7.5 12.6 7.5 6.3 1.1 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 CDS34615.2 - 5 4.9 7.9 6.4 4.5 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CDS34615.2 - 7.1 6.7 7.0 14 5.7 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ACCA PF03255.14 CDS34615.2 - 8.7 6.2 8.2 7.2 6.5 4.8 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4473 PF14747.6 CDS34616.2 - 0.0066 17.0 0.4 26 5.5 0.0 4.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4473) IMUP PF15761.5 CDS34616.2 - 0.068 13.9 0.0 35 5.1 0.0 3.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein UBZ_FAAP20 PF15750.5 CDS34616.2 - 0.15 12.0 2.6 18 5.4 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger nsp7 PF08716.10 CDS34616.2 - 0.45 11.2 2.6 48 4.7 0.1 3.3 3 0 0 3 3 3 0 nsp7 replicase Phage_TAC_6 PF09550.10 CDS34616.2 - 3.8 8.0 6.4 3.7 8.0 0.3 3.4 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC Thioredoxin PF00085.20 CDS34617.1 - 1.1e-49 166.6 0.0 3.3e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CDS34617.1 - 1.6e-14 54.2 0.0 1.4e-06 28.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CDS34617.1 - 7.2e-08 32.9 0.8 0.012 16.1 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDS34617.1 - 1.7e-07 30.9 0.0 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CDS34617.1 - 2e-06 28.0 0.4 0.089 13.1 0.2 4.2 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CDS34617.1 - 2.1e-05 24.3 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CDS34617.1 - 4e-05 23.7 0.1 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 CDS34617.1 - 9e-05 22.5 0.0 0.51 10.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 CDS34617.1 - 0.00016 21.5 0.1 0.32 10.9 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Fmp27_SW PF10305.9 CDS34617.1 - 0.012 16.3 0.0 0.044 14.5 0.0 2.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HyaE PF07449.11 CDS34617.1 - 0.013 15.5 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CDS34617.1 - 0.036 13.9 0.0 33 4.2 0.0 3.1 3 0 0 3 3 3 0 F plasmid transfer operon protein BNIP3 PF06553.12 CDS34617.1 - 0.11 12.2 1.9 0.46 10.1 0.8 2.2 3 0 0 3 3 3 0 BNIP3 Helicase_C PF00271.31 CDS34618.1 - 1.1e-20 74.0 0.1 6.5e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 CDS34618.1 - 6.5e-16 58.6 0.0 2e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 CDS34618.1 - 6.4e-07 29.2 3.4 1.5e-06 28.0 3.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDS34618.1 - 0.0064 16.4 0.4 0.018 15.0 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDS34618.1 - 2 8.2 7.4 0.36 10.6 2.7 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CDS34618.1 - 2.5 8.0 6.7 0.54 10.1 2.8 2.0 2 0 0 2 2 2 0 Zinc knuckle NTP_transf_2 PF01909.23 CDS34622.2 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDS34622.2 - 0.0024 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 CDS34622.2 - 0.088 13.0 5.6 1 9.6 5.6 2.3 1 1 0 1 1 1 0 Cid1 family poly A polymerase Bravo_FIGEY PF13882.6 CDS34628.2 - 1.3e-18 68.2 0.1 1.3e-18 68.2 0.1 2.9 3 0 0 3 3 3 1 Bravo-like intracellular region Btz PF09405.10 CDS34628.2 - 1e-06 29.1 5.5 1e-06 29.1 5.5 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DEAD PF00270.29 CDS34629.2 - 4e-41 140.7 0.0 7e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS34629.2 - 4.7e-24 84.9 0.0 1.4e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS34629.2 - 6.7e-09 36.0 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CDS34629.2 - 7.2e-06 26.1 0.0 2.3e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 CDS34629.2 - 0.00027 20.2 0.0 0.00056 19.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CDS34629.2 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain PC4 PF02229.16 CDS34632.1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) IL3 PF02059.15 CDS34632.1 - 0.11 12.5 0.5 0.56 10.3 0.0 2.3 2 2 0 2 2 2 0 Interleukin-3 zinc_ribbon_10 PF10058.9 CDS34635.1 - 1.2e-10 40.9 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF1773 PF08593.10 CDS34635.1 - 0.12 13.4 0.7 0.24 12.5 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function PC4 PF02229.16 CDS34637.1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) IL3 PF02059.15 CDS34637.1 - 0.11 12.5 0.5 0.56 10.3 0.0 2.3 2 2 0 2 2 2 0 Interleukin-3 Exo5 PF09810.9 CDS34638.1 - 0.018 14.6 0.2 0.021 14.3 0.2 1.0 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DEK_C PF08766.11 CDS34638.1 - 0.035 14.0 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 DEK C terminal domain Orf78 PF06024.12 CDS34638.1 - 0.075 13.3 0.2 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Homeobox_KN PF05920.11 CDS34639.1 - 1.2e-18 66.7 1.6 1.7e-17 63.0 1.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CDS34639.1 - 2.2e-08 33.8 0.1 4.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Pik1 PF11522.8 CDS34639.1 - 0.072 13.1 0.8 12 6.0 0.3 2.7 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 DEAD PF00270.29 CDS34640.2 - 6.1e-41 140.1 0.0 1e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS34640.2 - 4.3e-24 85.0 0.0 1.4e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS34640.2 - 6.7e-09 36.0 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CDS34640.2 - 7.1e-06 26.2 0.0 2.3e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 CDS34640.2 - 0.00027 20.2 0.0 0.00056 19.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CDS34640.2 - 0.0012 18.2 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain Bravo_FIGEY PF13882.6 CDS34641.2 - 1.3e-18 68.2 0.1 1.3e-18 68.2 0.1 2.8 3 0 0 3 3 3 1 Bravo-like intracellular region Btz PF09405.10 CDS34641.2 - 2.8e-07 30.9 2.1 2.8e-07 30.9 2.1 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Spem1 PF15670.5 CDS34641.2 - 0.89 9.1 17.4 2.9 7.4 17.4 1.9 1 0 0 1 1 1 0 Spermatid maturation protein 1 RED_N PF07808.13 CDS34644.1 - 8.1e-80 267.8 10.8 8.1e-80 267.8 10.8 2.6 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 CDS34644.1 - 1.1e-48 164.4 6.3 2.5e-48 163.2 3.0 3.1 2 0 0 2 2 2 1 RED-like protein C-terminal region Lsm_interact PF05391.11 CDS34644.1 - 3.4e-07 29.5 0.2 1.6e-06 27.4 0.2 2.3 1 0 0 1 1 1 1 Lsm interaction motif Trypan_PARP PF05887.11 CDS34644.1 - 1.1 9.3 6.6 0.16 11.9 0.5 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) NTP_transf_2 PF01909.23 CDS34647.2 - 9.1e-08 32.3 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDS34647.2 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 CDS34647.2 - 0.083 13.1 5.1 0.85 9.9 5.1 2.2 1 1 0 1 1 1 0 Cid1 family poly A polymerase Mito_fiss_reg PF05308.11 CDS34647.2 - 2 8.4 5.4 4.5 7.3 5.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Hemocyanin_M PF00372.19 CDS34655.1 - 0.034 13.4 0.0 0.035 13.3 0.0 1.0 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Collagen PF01391.18 CDS34657.1 - 2.3e-160 520.5 670.9 6.1e-09 35.5 26.3 21.4 2 1 10 12 12 12 7 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CDS34657.1 - 7e-42 143.3 0.0 9.7e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.24 CDS34657.1 - 0.00052 20.6 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain SR-25 PF10500.9 CDS34658.1 - 4e-08 33.1 25.3 4e-08 33.1 25.3 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein SH3_9 PF14604.6 CDS34658.1 - 7.9e-05 22.4 0.0 0.00025 20.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SOBP PF15279.6 CDS34658.1 - 0.00099 19.8 18.2 0.00099 19.8 18.2 2.7 3 0 0 3 3 3 1 Sine oculis-binding protein SH3_2 PF07653.17 CDS34658.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS34658.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CDS34658.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_1 PF00076.22 CDS34659.1 - 2.3e-14 53.0 0.0 3.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDS34659.1 - 1.3e-06 28.0 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.7 CDS34659.1 - 0.069 13.2 0.1 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) zf-C2H2 PF00096.26 CDS34661.1 - 1.8e-11 43.8 18.6 0.0001 22.6 1.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34661.1 - 1.5e-09 37.9 15.7 0.0063 17.2 1.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34661.1 - 0.00023 21.4 16.8 0.00075 19.8 1.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDS34661.1 - 0.00067 19.4 1.1 0.00067 19.4 1.1 4.0 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CDS34661.1 - 0.001 19.0 12.2 0.04 13.9 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 CDS34661.1 - 0.0084 16.1 14.3 0.69 10.0 1.4 3.6 1 1 2 3 3 3 2 BED zinc finger zf-Di19 PF05605.12 CDS34661.1 - 0.0085 16.4 5.1 0.0085 16.4 5.1 2.8 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CDS34661.1 - 0.029 14.8 8.4 0.74 10.3 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CDS34661.1 - 0.076 13.5 12.1 0.28 11.6 0.2 3.7 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-FCS PF06467.14 CDS34661.1 - 0.085 12.8 5.7 15 5.7 0.4 3.5 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF629 PF04780.12 CDS34661.1 - 0.26 9.8 6.5 3.5 6.1 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Yippee-Mis18 PF03226.14 CDS34661.1 - 0.39 11.0 3.9 1 9.6 3.9 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-AN1 PF01428.16 CDS34661.1 - 0.47 10.7 8.6 11 6.2 0.3 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger GAGA PF09237.11 CDS34661.1 - 0.61 9.9 3.4 12 5.8 0.2 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.7 CDS34661.1 - 0.69 10.3 10.5 0.3 11.4 0.8 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 CDS34661.1 - 0.9 9.8 9.0 3.4 8.0 0.2 3.0 1 1 0 2 2 2 0 LIM domain zf-C2H2_3rep PF18868.1 CDS34661.1 - 1.5 9.5 10.0 5.7 7.6 0.1 3.5 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CDS34661.1 - 1.6 8.6 15.9 1 9.2 2.9 3.6 3 1 1 4 4 4 0 zinc-finger C2H2-type Actin_micro PF17003.5 CDS34661.1 - 1.9 7.6 5.7 7 5.7 5.8 1.9 1 1 0 1 1 1 0 Putative actin-like family zinc_ribbon_10 PF10058.9 CDS34661.1 - 3.1 7.6 5.4 0.55 10.0 1.3 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2H2 PF00096.26 CDS34662.1 - 0.0001 22.6 9.6 0.00037 20.8 3.3 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34662.1 - 0.0004 21.0 9.3 0.005 17.6 3.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-AN1 PF01428.16 CDS34662.1 - 0.029 14.5 7.3 0.07 13.3 0.5 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zinc_ribbon_10 PF10058.9 CDS34662.1 - 0.064 13.0 0.6 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2HE PF16278.5 CDS34662.1 - 0.75 10.3 7.5 1.5 9.4 0.5 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 CDS34662.1 - 1.2 9.9 5.6 1.7 9.4 0.6 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Herpes_UL56 PF04534.12 CDS34665.2 - 0.055 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF2373 PF10180.9 CDS34672.2 - 0.016 15.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Herpes_UL56 PF04534.12 CDS34672.2 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Sin_N PF04801.13 CDS34678.1 - 1.9e-27 96.6 1.7 2.3e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 Sin-like protein conserved region POT1 PF02765.17 CDS34678.1 - 3.7e-12 46.3 0.0 1.6e-10 40.9 0.0 2.6 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 CDS34678.1 - 1.6e-10 41.0 0.0 4.3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein PXB PF12828.7 CDS34678.1 - 0.036 14.1 0.9 0.12 12.3 0.3 2.1 2 0 0 2 2 2 0 PX-associated Codanin-1_C PF15296.6 CDS34678.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Codanin-1 C-terminus Complex1_LYR PF05347.15 CDS34679.1 - 4.6e-10 39.4 1.1 8.9e-10 38.5 1.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDS34679.1 - 0.006 17.3 0.4 0.006 17.3 0.4 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Acetyltransf_9 PF13527.7 CDS34679.1 - 0.12 12.4 0.1 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PH PF00169.29 CDS34680.1 - 7.7e-13 48.9 0.1 5.9e-08 33.2 0.3 3.0 2 1 0 2 2 2 2 PH domain MyTH4 PF00784.17 CDS34680.1 - 1.9e-11 44.4 0.1 0.00015 22.2 0.0 2.7 2 0 0 2 2 2 2 MyTH4 domain NABP PF07990.12 CDS34680.1 - 0.0096 15.5 1.8 0.019 14.5 1.8 1.4 1 0 0 1 1 1 1 Nucleic acid binding protein NABP Orthopox_F8 PF05886.11 CDS34680.1 - 0.22 11.7 2.6 0.88 9.7 2.6 2.0 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Adenylsucc_synt PF00709.21 CDS34684.1 - 4.5e-172 572.7 0.0 5.1e-172 572.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase C2 PF00168.30 CDS34685.2 - 0.00025 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF1899 PF08953.11 CDS34686.2 - 1.9e-29 101.3 0.0 3.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CDS34686.2 - 5.5e-20 71.0 0.0 9.6e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CDS34686.2 - 2e-13 50.6 6.6 0.0002 22.1 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34686.2 - 3.8e-06 27.1 0.1 0.0092 16.3 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS34686.2 - 0.014 14.4 0.0 0.67 8.9 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADIP PF11559.8 CDS34686.2 - 0.027 14.6 0.7 0.044 13.9 0.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.11 CDS34686.2 - 0.14 12.0 0.7 0.31 11.0 0.7 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region rve PF00665.26 CDS34688.1 - 8.5e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain MCM6_C PF18263.1 CDS34690.1 - 0.12 12.7 0.1 0.99 9.7 0.1 2.4 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain FNIP_M PF14637.6 CDS34691.2 - 2e-16 60.7 0.8 7.1e-15 55.6 0.7 3.1 2 1 0 2 2 2 1 Folliculin-interacting protein middle domain Ribosomal_S9 PF00380.19 CDS34693.1 - 3.4e-30 105.0 0.0 3.9e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 WIF PF02019.18 CDS34694.1 - 8.5e-16 57.8 0.0 1.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 WIF domain Ion_trans PF00520.31 CDS34695.1 - 3.6e-12 46.0 5.2 5.6e-12 45.4 5.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CDS34695.1 - 0.026 14.5 1.6 0.026 14.5 1.6 2.2 2 1 0 2 2 2 0 Ion channel Peptidase_M24 PF00557.24 CDS34697.2 - 2.3e-42 145.1 0.2 3.2e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Trypsin PF00089.26 CDS34698.2 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CDS34698.2 - 0.13 12.7 0.1 0.71 10.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Cadherin PF00028.17 CDS34699.2 - 9.2e-48 160.6 0.0 9.8e-22 77.2 0.0 4.1 4 0 0 4 4 4 3 Cadherin domain Cadherin_2 PF08266.12 CDS34699.2 - 3.4e-05 23.6 0.0 0.066 13.1 0.0 4.0 4 0 0 4 4 4 1 Cadherin-like Cadherin_3 PF16184.5 CDS34699.2 - 9.8e-05 22.3 0.3 2.9 7.9 0.0 3.9 3 0 0 3 3 3 2 Cadherin-like DUF4097 PF13349.6 CDS34699.2 - 0.02 14.3 0.9 0.062 12.6 0.5 2.0 1 1 1 2 2 2 0 Putative adhesin DUF4307 PF14155.6 CDS34699.2 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) MGAT2 PF05060.14 CDS34700.1 - 7.3e-35 120.6 0.1 9.4e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Na_K-ATPase PF00287.18 CDS34705.1 - 9.9e-24 84.0 2.3 1.2e-23 83.7 2.3 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Ribosomal_S8e PF01201.22 CDS34707.1 - 9.9e-54 181.2 0.5 1.2e-53 181.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e MitMem_reg PF13012.6 CDS34708.1 - 1.2e-13 51.5 0.9 3.1e-13 50.1 0.4 2.0 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDS34708.1 - 3e-09 36.9 0.9 6.8e-09 35.7 0.2 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HECT PF00632.25 CDS34709.1 - 1.1e-51 176.2 0.0 2.4e-51 175.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.8 CDS34709.1 - 4.3e-31 106.3 1.0 1.1e-30 105.0 1.0 1.8 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD zf-UBR PF02207.20 CDS34709.1 - 0.0046 17.1 21.0 0.01 16.0 21.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Na_K-ATPase PF00287.18 CDS34711.1 - 9.9e-24 84.0 2.3 1.2e-23 83.7 2.3 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain WD40 PF00400.32 CDS34712.2 - 0.00078 20.2 0.3 0.56 11.2 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L14e PF01929.17 CDS34712.2 - 0.015 15.8 0.4 0.041 14.4 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein L14 CRM1_C PF08767.11 CDS34713.2 - 5.7e-107 357.6 6.7 5.7e-107 357.6 6.7 2.4 3 0 0 3 3 3 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 CDS34713.2 - 3.2e-35 119.6 2.5 6.1e-35 118.7 1.5 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CDS34713.2 - 6.9e-27 93.3 1.9 1.4e-26 92.3 0.5 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CDS34713.2 - 1.1e-17 63.3 6.2 2.6e-17 62.0 6.2 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat MnmE_helical PF12631.7 CDS34713.2 - 0.016 15.4 1.6 0.54 10.4 0.3 2.9 2 1 0 2 2 2 0 MnmE helical domain Ribosomal_S8e PF01201.22 CDS34714.1 - 9.9e-54 181.2 0.5 1.2e-53 181.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e MitMem_reg PF13012.6 CDS34715.1 - 1.2e-13 51.5 0.9 3.1e-13 50.1 0.4 2.0 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDS34715.1 - 3e-09 36.9 0.9 6.8e-09 35.7 0.2 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease E3_UbLigase_EDD PF11547.8 CDS34716.2 - 2.7e-62 206.3 7.8 1.6e-30 104.6 1.0 2.9 2 0 0 2 2 2 2 E3 ubiquitin ligase EDD HECT PF00632.25 CDS34716.2 - 1.7e-51 175.6 0.0 3.4e-51 174.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NLRC4_HD2 PF17776.1 CDS34716.2 - 0.003 18.1 0.1 5.8 7.5 0.0 2.7 2 0 0 2 2 2 2 NLRC4 helical domain HD2 zf-UBR PF02207.20 CDS34716.2 - 0.0063 16.7 21.0 0.014 15.5 21.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF1296 PF06972.11 CDS34716.2 - 0.016 15.3 0.5 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) KORA PF16509.5 CDS34716.2 - 0.029 14.7 0.2 15 5.9 0.0 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor SRR1 PF07985.12 CDS34716.2 - 0.11 12.6 0.0 32 4.6 0.0 2.8 2 0 0 2 2 2 0 SRR1 DUF3008 PF11450.8 CDS34716.2 - 1.2 9.3 4.0 33 4.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) ATG101 PF07855.12 CDS34718.1 - 2.5e-29 102.2 0.0 3.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Mononeg_mRNAcap PF14318.6 CDS34718.1 - 0.065 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V G-patch_2 PF12656.7 CDS34721.1 - 1.1e-14 54.2 0.0 2.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 CDS34721.1 - 6.3e-06 25.9 12.2 0.00041 20.2 0.1 3.4 4 0 0 4 4 4 2 KOW motif GDA1_CD39 PF01150.17 CDS34725.2 - 7.3e-80 268.7 0.0 9.8e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4179 PF13786.6 CDS34725.2 - 0.064 13.7 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Vps5 PF09325.10 CDS34726.2 - 2e-44 151.9 6.4 2e-44 151.9 6.4 3.0 2 1 1 3 3 2 1 Vps5 C terminal like TACC_C PF05010.14 CDS34726.2 - 8.2e-40 136.8 23.6 8.2e-40 136.8 23.6 2.3 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4992 PF16383.5 CDS34726.2 - 0.00081 19.0 0.9 15 5.1 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function APG6_N PF17675.1 CDS34726.2 - 0.0013 19.3 16.8 0.0013 19.3 16.8 3.5 2 2 1 3 3 3 1 Apg6 coiled-coil region Caskin-Pro-rich PF16907.5 CDS34726.2 - 0.02 15.4 28.6 0.31 11.6 1.0 4.6 5 0 0 5 5 5 0 Proline rich region of Caskin proteins PX PF00787.24 CDS34726.2 - 0.022 14.8 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 PX domain FPP PF05911.11 CDS34726.2 - 0.24 9.5 23.1 0.0076 14.5 16.9 1.6 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 CDS34726.2 - 0.74 9.3 31.5 0.15 11.6 20.3 2.9 2 1 1 3 3 3 0 Intermediate filament protein DUF5082 PF16888.5 CDS34726.2 - 2.2 8.6 20.9 0.52 10.6 15.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Bac_GDH PF05088.12 CDS34726.2 - 3 5.2 17.1 0.26 8.7 0.7 2.1 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase LMBR1 PF04791.16 CDS34726.2 - 4.9 5.9 9.6 0.33 9.8 4.5 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Macoilin PF09726.9 CDS34726.2 - 5 5.5 16.4 0.13 10.8 8.0 2.1 2 0 0 2 2 2 0 Macoilin family Glyco_transf_7C PF02709.14 CDS34729.1 - 4.1e-19 68.0 0.2 8.7e-19 67.0 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CDS34729.1 - 5.1e-19 68.2 0.2 2.2e-18 66.2 0.2 1.9 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 CDS34729.1 - 0.025 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ATG101 PF07855.12 CDS34730.1 - 2.5e-29 102.2 0.0 3.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Mononeg_mRNAcap PF14318.6 CDS34730.1 - 0.065 12.5 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V DUF4044 PF13253.6 CDS34734.2 - 0.088 12.3 0.3 0.088 12.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) TMEM208_SND2 PF05620.11 CDS34734.2 - 2 8.2 8.1 0.11 12.3 0.5 2.2 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2151 PF10221.9 CDS34739.1 - 5.3e-40 137.7 0.0 6.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator Sgf11_N PF18519.1 CDS34739.1 - 0.037 13.6 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain Innexin PF00876.18 CDS34743.1 - 2.1e-97 326.6 4.6 2.5e-97 326.3 4.6 1.0 1 0 0 1 1 1 1 Innexin DPM3 PF08285.11 CDS34743.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.1 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF5381 PF17353.2 CDS34743.1 - 8.8 6.0 7.7 14 5.4 0.7 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5381) CLP1_P PF16575.5 CDS34744.1 - 2.2e-35 122.2 0.0 5.8e-35 120.8 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 CDS34744.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 CDS34744.1 - 0.0055 16.6 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 CDS34744.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_35 PF14516.6 CDS34744.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 CDS34744.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDS34744.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CDS34744.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDS34744.1 - 0.031 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA12 PF10443.9 CDS34744.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.6 CDS34744.1 - 0.097 12.7 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDS34744.1 - 0.099 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CDS34744.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Dynamin family zf-AN1 PF01428.16 CDS34745.1 - 3.8e-21 74.9 27.8 4.1e-12 46.0 7.4 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CDS34745.1 - 3.7e-05 24.0 18.3 0.019 15.3 5.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain UIM PF02809.20 CDS34745.1 - 0.011 15.6 1.1 0.011 15.6 1.1 1.8 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF530 PF04409.12 CDS34745.1 - 1.2 7.4 5.1 1.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF530) DUF2151 PF10221.9 CDS34747.1 - 4.1e-17 62.1 0.0 4.2e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator Got1 PF04178.12 CDS34748.1 - 1.3e-14 54.6 12.4 1.7e-14 54.2 12.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family 2OG-FeII_Oxy_2 PF13532.6 CDS34749.1 - 1.8e-07 31.5 0.0 2.8e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily STT3 PF02516.14 CDS34750.1 - 9.2e-130 433.8 39.2 1.8e-124 416.4 35.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF4209 PF13910.6 CDS34752.2 - 7.7e-14 51.7 1.9 5.5e-12 45.7 0.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Peptidase_S8 PF00082.22 CDS34753.2 - 2.2e-17 63.3 0.3 3e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 CDS34753.2 - 6.6e-05 23.6 0.2 0.00013 22.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF3362 PF11842.8 CDS34753.2 - 0.17 12.2 0.4 0.4 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) Fasciclin PF02469.22 CDS34757.1 - 3.7e-11 43.3 0.2 0.016 15.4 0.0 4.7 4 1 0 4 4 4 4 Fasciclin domain Dynein_light PF01221.18 CDS34758.1 - 5.8e-12 45.8 0.0 7.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1639 PF07797.14 CDS34758.1 - 0.092 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Dynein_light PF01221.18 CDS34759.1 - 0.0001 22.5 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS34768.1 - 6.6e-15 55.2 0.2 9.7e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 TetR_C_37 PF18665.1 CDS34768.1 - 0.045 14.4 0.0 0.085 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Dynein_light PF01221.18 CDS34769.2 - 1.8e-08 34.6 0.0 2.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 CBM_15 PF03426.14 CDS34769.2 - 0.089 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) EF-hand_7 PF13499.6 CDS34769.2 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Dynein_light PF01221.18 CDS34770.1 - 9.4e-22 77.1 0.0 1.3e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 Dynein light chain type 1 FeoB_Cyto PF17910.1 CDS34770.1 - 0.0036 17.8 0.0 0.057 14.0 0.0 2.2 2 0 0 2 2 2 1 FeoB cytosolic helical domain DUF3646 PF12362.8 CDS34770.1 - 0.021 15.1 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal EF-hand_1 PF00036.32 CDS34770.1 - 0.11 12.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 EF hand Ground-like PF04155.18 CDS34770.1 - 0.11 13.1 0.0 1.3 9.7 0.0 2.3 2 0 0 2 2 2 0 Ground-like domain EB1 PF03271.17 CDS34770.1 - 0.4 11.0 2.0 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 EB1-like C-terminal motif Dynein_light PF01221.18 CDS34771.1 - 0.0001 22.5 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Dynein_light PF01221.18 CDS34772.1 - 5.8e-12 45.8 0.0 7.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1639 PF07797.14 CDS34772.1 - 0.092 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Fasciclin PF02469.22 CDS34773.2 - 3.7e-11 43.3 0.2 0.016 15.4 0.0 4.7 4 1 0 4 4 4 4 Fasciclin domain Ig_3 PF13927.6 CDS34774.2 - 6.6e-24 84.3 0.1 9.8e-10 38.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CDS34774.2 - 4.2e-23 81.2 0.0 2.5e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 CDS34774.2 - 3.5e-19 68.8 0.1 2.1e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CDS34774.2 - 2.1e-15 56.8 0.3 2.2e-06 27.8 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_2 PF13895.6 CDS34774.2 - 3.5e-13 49.7 0.5 5.4e-06 26.6 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin domain Ig_6 PF18452.1 CDS34774.2 - 0.0027 17.2 0.0 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.12 CDS34774.2 - 0.019 15.1 0.0 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain UBA PF00627.31 CDS34776.2 - 0.0044 16.9 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 UBA/TS-N domain WW PF00397.26 CDS34777.1 - 0.00038 20.5 4.5 0.54 10.4 0.0 3.5 3 0 0 3 3 3 3 WW domain PLDc_3 PF13918.6 CDS34780.2 - 1e-29 103.4 0.0 1.7e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.6 CDS34780.2 - 1.4e-25 89.7 0.0 3e-12 46.6 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDS34780.2 - 4.4e-12 45.7 2.5 2.1e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Ost5 PF05251.12 CDS34780.2 - 0.05 13.9 0.8 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 PDCD9 PF07147.12 CDS34781.1 - 2.8e-13 49.9 0.0 9.1e-07 28.4 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial 28S ribosomal protein S30 (PDCD9) 2-Hacid_dh_C PF02826.19 CDS34782.1 - 2.4e-45 154.1 0.0 4.9e-45 153.1 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDS34782.1 - 6.4e-25 87.4 0.0 7.4e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 CDS34782.1 - 0.069 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family JmjC PF02373.22 CDS34783.2 - 8.3e-27 93.9 0.6 3.6e-25 88.6 0.0 3.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 CDS34783.2 - 3e-07 30.7 24.7 5.7e-06 26.6 2.0 4.1 4 0 0 4 4 4 3 C5HC2 zinc finger Metal_resist PF13801.6 CDS34792.1 - 0.19 12.0 0.0 0.94 9.7 0.0 2.0 3 0 0 3 3 3 0 Heavy-metal resistance GAS PF13851.6 CDS34793.2 - 0.0075 15.6 1.8 0.68 9.3 0.0 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding APG17 PF04108.12 CDS34793.2 - 0.011 14.9 0.7 0.014 14.5 0.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 STAT_alpha PF01017.20 CDS34793.2 - 0.043 13.7 0.9 0.056 13.3 0.9 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain Baculo_PEP_C PF04513.12 CDS34793.2 - 0.078 13.0 1.5 4.7 7.2 0.1 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Halo_GVPC PF05465.13 CDS34793.2 - 0.086 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Retrotrans_gag PF03732.17 CDS34793.2 - 0.11 12.7 0.3 4 7.8 0.3 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein Bacillus_HBL PF05791.11 CDS34793.2 - 0.2 11.5 1.3 1.8 8.4 0.7 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0113_N PF17833.1 CDS34800.2 - 7e-27 93.8 1.6 9.4e-27 93.4 1.6 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDS34800.2 - 5e-10 39.5 0.0 9.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain Deltameth_res PF16020.5 CDS34801.1 - 4.3e-17 61.7 0.1 5.9e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Deltamethrin resistance Rrp44_CSD1 PF17216.3 CDS34807.1 - 0.071 12.8 0.4 0.075 12.7 0.4 1.1 1 0 0 1 1 1 0 Rrp44-like cold shock domain Shisa PF13908.6 CDS34814.1 - 0.024 14.9 0.4 0.03 14.6 0.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator WIF PF02019.18 CDS34817.1 - 0.037 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 WIF domain Phage_holin_2_1 PF04971.12 CDS34820.1 - 0.02 14.9 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S Phage_holin_2_3 PF16080.5 CDS34820.1 - 0.08 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Inositol_P PF00459.25 CDS34824.1 - 2.3e-28 99.5 0.0 4.9e-28 98.4 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DNA_pol_P_Exo PF18049.1 CDS34824.1 - 0.049 13.0 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo WD40 PF00400.32 CDS34825.1 - 2.7e-26 91.3 10.0 2.6e-11 43.9 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34825.1 - 1.1e-12 48.1 0.0 4.5e-05 23.7 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CDS34825.1 - 2.8e-05 22.7 0.0 8.8e-05 21.0 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CDS34825.1 - 0.00015 20.9 0.0 0.028 13.4 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CDS34825.1 - 0.088 10.8 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Proteasome_A_N PF10584.9 CDS34825.1 - 0.18 11.5 0.0 0.58 9.9 0.0 1.9 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature RMI2 PF16100.5 CDS34826.1 - 6.3e-09 35.7 0.0 1.9e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 CDS34826.1 - 0.027 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-C2H2 PF00096.26 CDS34828.1 - 1e-39 132.8 52.9 4.2e-06 26.9 0.9 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDS34828.1 - 1.4e-30 103.3 50.2 0.00011 22.8 1.9 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS34828.1 - 3.2e-29 100.0 46.7 6.4e-06 26.4 0.9 9.1 9 0 0 9 9 9 8 Zinc-finger double domain zf-met PF12874.7 CDS34828.1 - 6.2e-16 58.2 34.2 0.041 14.3 0.2 8.2 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS34828.1 - 1.1e-15 57.4 37.1 0.0038 17.5 1.1 8.2 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS34828.1 - 2.6e-14 52.8 47.1 0.0012 18.8 0.3 9.1 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDS34828.1 - 1.5e-06 27.8 35.7 0.18 11.6 0.2 7.8 8 0 0 8 8 8 4 zinc-finger C2H2-type zf-Di19 PF05605.12 CDS34828.1 - 2.2e-06 27.9 37.6 0.00035 20.8 5.1 4.6 4 1 0 5 5 4 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 CDS34828.1 - 6e-06 26.3 42.2 0.088 13.0 0.8 8.2 7 1 1 8 8 8 3 AN1-like Zinc finger zf_UBZ PF18439.1 CDS34828.1 - 0.00034 20.1 31.5 0.18 11.5 0.1 7.9 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 CDS34828.1 - 0.00042 21.0 28.9 0.021 15.5 1.1 5.5 1 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 CDS34828.1 - 0.0011 19.0 34.6 0.19 11.8 1.7 7.2 4 2 3 7 7 7 3 BED zinc finger zf-C2HE PF16278.5 CDS34828.1 - 0.0053 17.2 41.0 0.21 12.1 2.6 7.9 2 1 5 7 7 7 2 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 CDS34828.1 - 0.0074 16.3 26.4 0.19 11.8 1.9 6.3 2 2 5 7 7 7 2 CpXC protein Zn_ribbon_SprT PF17283.2 CDS34828.1 - 0.013 15.4 1.3 0.013 15.4 1.3 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain PyrI_C PF02748.15 CDS34828.1 - 0.018 15.0 31.1 0.22 11.4 0.2 6.7 6 2 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 CDS34828.1 - 0.054 13.4 35.2 2.3 8.2 0.6 7.5 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 CDS34828.1 - 0.12 12.4 0.7 0.12 12.4 0.7 4.8 7 0 0 7 7 6 0 Zinc-finger domain zf-H2C2_5 PF13909.6 CDS34828.1 - 0.22 11.3 48.0 0.81 9.5 0.8 8.5 8 1 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 CDS34828.1 - 0.39 11.0 31.2 1.6 9.1 5.0 4.6 1 1 4 5 5 5 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 CDS34828.1 - 2.3 8.4 36.5 1.7 8.8 1.9 6.2 3 2 4 7 7 7 0 Zinc ribbon domain Elf1 PF05129.13 CDS34828.1 - 3.6 7.7 32.1 0.24 11.5 2.5 5.3 1 1 3 4 4 3 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 CDS34828.1 - 4.5 7.2 25.5 0.22 11.4 1.7 6.0 6 1 0 6 6 6 0 Transcription factor S-II (TFIIS) DUF2256 PF10013.9 CDS34828.1 - 8.2 6.6 26.6 3 8.1 0.2 6.6 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) FYDLN_acid PF09538.10 CDS34828.1 - 9.3 7.0 16.0 36 5.1 0.7 5.7 1 1 7 8 8 8 0 Protein of unknown function (FYDLN_acid) SICA_C PF12879.7 CDS34830.1 - 0.25 11.4 2.0 0.35 10.9 1.7 1.3 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain RhoGAP PF00620.27 CDS34832.2 - 1.6e-34 118.9 0.0 2.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ANP PF00212.18 CDS34832.2 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Atrial natriuretic peptide CRAL_TRIO PF00650.20 CDS34833.1 - 4.1e-31 107.8 0.0 6.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CDS34833.1 - 3.2e-07 30.9 0.0 7.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 CDS34833.1 - 0.00042 20.4 2.0 0.00097 19.3 2.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 CDS34840.2 - 6e-24 84.6 0.0 1.4e-19 70.4 0.0 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain GOLD_2 PF13897.6 CDS34840.2 - 3e-07 31.0 0.0 6.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 CDS34840.2 - 0.0004 20.5 2.0 0.00092 19.3 2.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1759 PF03564.15 CDS34845.2 - 0.011 15.7 1.3 0.011 15.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) NDUFB10 PF10249.9 CDS34845.2 - 0.24 11.9 4.5 0.17 12.4 1.6 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 Pkinase PF00069.25 CDS34847.2 - 3.9e-20 72.3 0.2 7.2e-12 45.2 0.1 3.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34847.2 - 3.2e-09 36.4 0.0 2.3e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CDS34848.2 - 2.2e-14 53.5 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDS34848.2 - 2.2e-07 30.0 0.1 2.8e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDS34848.2 - 1.6e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS34848.2 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CDS34849.2 - 2.2e-14 53.5 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDS34849.2 - 2.2e-07 30.0 0.1 2.8e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDS34849.2 - 1.6e-06 27.6 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDS34849.2 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CNH PF00780.22 CDS34850.2 - 6.6e-34 117.8 0.0 1.7e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 CNH domain Pkinase PF00069.25 CDS34850.2 - 5.2e-20 71.9 0.2 8.1e-12 45.1 0.1 3.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDS34850.2 - 3.8e-09 36.2 0.0 4.2e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase SNAPc_SNAP43 PF09808.9 CDS34851.1 - 9.5e-32 110.5 0.5 2.6e-31 109.1 0.5 1.7 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF4096 PF13340.6 CDS34851.1 - 0.1 12.8 0.0 5.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) RNA_pol_Rpb2_2 PF04561.14 CDS34858.1 - 0.19 11.3 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 GLTP PF08718.11 CDS34864.1 - 1.6e-19 70.7 0.0 1.7e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LRR_8 PF13855.6 CDS34865.1 - 1.4e-16 60.0 7.0 1.3e-06 28.1 0.6 3.7 1 1 1 3 3 3 3 Leucine rich repeat I-set PF07679.16 CDS34865.1 - 4.3e-09 36.3 0.3 2.5e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CDS34865.1 - 5.2e-09 36.6 1.1 1.4e-07 32.0 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain LRR_4 PF12799.7 CDS34865.1 - 7.3e-08 32.6 8.0 0.006 17.0 2.9 4.1 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDS34865.1 - 4.1e-07 29.6 14.4 0.19 12.4 0.3 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat Ig_2 PF13895.6 CDS34865.1 - 1.4e-06 28.5 0.2 6.6e-06 26.4 0.2 2.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CDS34865.1 - 0.00016 21.8 0.1 0.0007 19.7 0.1 2.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CDS34865.1 - 0.00096 19.3 0.1 0.026 14.7 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 CDS34865.1 - 0.032 14.3 3.8 11 6.4 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich repeat Insulin_TMD PF17870.1 CDS34865.1 - 0.033 14.3 0.2 0.085 12.9 0.2 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HeH PF12949.7 CDS34869.1 - 0.047 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Mtc PF03820.17 CDS34872.1 - 1.5e-133 444.7 0.0 1.7e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Disintegrin PF00200.23 CDS34875.2 - 3.2e-19 69.5 27.2 3.2e-19 69.5 27.2 3.7 4 0 0 4 4 4 1 Disintegrin Reprolysin PF01421.19 CDS34875.2 - 1.7e-15 57.5 1.3 1.7e-15 57.5 1.3 2.0 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CDS34875.2 - 1.2e-07 32.1 1.4 3.2e-07 30.7 1.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDS34875.2 - 1.3e-07 32.2 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDS34875.2 - 9.7e-05 22.1 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CDS34875.2 - 0.00079 19.4 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CDS34875.2 - 0.018 15.0 0.2 0.032 14.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.24 CDS34875.2 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 CDS34875.2 - 0.12 11.5 0.3 0.21 10.8 0.3 1.3 1 0 0 1 1 1 0 Met-zincin Mtc PF03820.17 CDS34877.1 - 1.5e-133 444.7 0.0 1.7e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier MgtE PF01769.16 CDS34878.1 - 1.9e-06 28.3 15.7 0.0015 18.9 0.1 4.2 3 2 1 4 4 4 2 Divalent cation transporter Aft1_HRR PF11787.8 CDS34884.1 - 0.054 14.7 0.0 0.067 14.4 0.0 1.2 1 0 0 1 1 1 0 Aft1 HRR domain RPW8 PF05659.11 CDS34886.1 - 0.029 14.1 0.3 0.03 14.0 0.3 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Wx5_PLAF3D7 PF09688.10 CDS34886.1 - 0.066 13.2 0.1 0.083 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) SpecificRecomb PF10136.9 CDS34886.1 - 0.091 11.1 0.3 0.097 11.0 0.3 1.0 1 0 0 1 1 1 0 Site-specific recombinase IP_trans PF02121.18 CDS34890.2 - 1.1e-99 333.0 0.1 1.1e-99 333.0 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol transfer protein Peptidase_C2 PF00648.21 CDS34890.2 - 3.6e-44 151.0 0.0 6.2e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DDHD PF02862.17 CDS34890.2 - 3.7e-31 109.0 3.1 3.8e-31 109.0 0.0 2.5 3 0 0 3 3 3 1 DDHD domain Calpain_III PF01067.22 CDS34890.2 - 6.3e-12 45.9 0.5 0.00015 22.1 0.1 3.0 2 1 0 2 2 2 2 Calpain large subunit, domain III WND PF07861.11 CDS34890.2 - 0.024 14.1 0.0 8.9 5.7 0.0 2.4 2 0 0 2 2 2 0 WisP family N-Terminal Region WD40 PF00400.32 CDS34894.1 - 2.9e-14 53.2 0.8 0.15 13.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34894.1 - 0.00014 22.1 0.0 0.34 11.3 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 CDS34894.1 - 0.053 13.4 0.2 12 5.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) MRF_C2 PF13888.6 CDS34894.1 - 0.089 12.7 0.2 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 IP_trans PF02121.18 CDS34895.2 - 6.2e-188 622.1 6.7 1.1e-106 356.0 0.2 2.7 3 0 0 3 3 3 2 Phosphatidylinositol transfer protein DDHD PF02862.17 CDS34895.2 - 3.8e-32 112.2 0.3 2.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 1 DDHD domain Peptidase_C2 PF00648.21 CDS34895.2 - 7.5e-30 104.0 0.0 1.3e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease LNS2 PF08235.13 CDS34895.2 - 0.00085 18.9 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) PHD PF00628.29 CDS34897.2 - 1.6e-23 82.4 20.5 4.4e-13 48.9 6.3 6.0 6 0 0 6 6 4 2 PHD-finger zf-RING_2 PF13639.6 CDS34897.2 - 5.6e-20 71.4 100.5 6.5e-06 26.4 13.9 6.3 6 0 0 6 6 6 4 Ring finger domain zf-rbx1 PF12678.7 CDS34897.2 - 1.1e-17 64.0 72.6 3.7e-05 23.9 1.2 6.6 6 0 0 6 6 6 4 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDS34897.2 - 3.2e-10 39.9 58.5 0.091 12.8 1.7 6.4 6 0 0 6 6 6 6 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CDS34897.2 - 2.2e-09 37.0 89.4 0.0004 20.2 7.0 6.4 6 0 0 6 6 6 4 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS34897.2 - 0.00016 21.6 87.1 0.0012 18.8 7.9 5.6 6 0 0 6 6 4 4 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDS34897.2 - 0.00051 19.8 28.0 0.0024 17.7 10.0 6.4 6 0 0 6 6 6 2 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 CDS34897.2 - 0.0047 17.0 32.8 0.17 12.0 2.4 5.7 4 2 2 6 6 6 3 KIAA1045 RING finger DIL PF01843.19 CDS34897.2 - 0.007 16.6 0.1 14 6.0 0.0 3.7 4 0 0 4 4 4 0 DIL domain LMWPc PF01451.21 CDS34897.2 - 0.029 14.7 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase zf-RING_11 PF17123.5 CDS34897.2 - 0.17 11.7 43.1 0.14 11.9 3.5 4.9 4 0 0 4 4 4 0 RING-like zinc finger DUF4831 PF16115.5 CDS34897.2 - 0.21 10.6 0.7 16 4.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) zf-C3HC4_2 PF13923.6 CDS34897.2 - 0.74 9.7 92.1 0.019 14.8 15.2 6.3 6 0 0 6 6 4 0 Zinc finger, C3HC4 type (RING finger) zf-WRNIP1_ubi PF18279.1 CDS34897.2 - 5.1 8.0 5.6 74 4.3 0.5 3.2 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Acyltransferase PF01553.21 CDS34898.1 - 5.9e-26 90.7 0.3 8.7e-26 90.1 0.3 1.2 1 0 0 1 1 1 1 Acyltransferase zf-C4 PF00105.18 CDS34899.1 - 2.5e-29 101.5 16.7 4e-29 100.9 16.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CDS34899.1 - 5.2e-13 49.1 0.0 1.5e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor 3HCDH_RFF PF18321.1 CDS34899.1 - 0.15 12.6 0.2 0.41 11.1 0.2 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain CPT_N PF16484.5 CDS34901.1 - 0.095 12.7 0.1 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus Collagen PF01391.18 CDS34905.1 - 4.1e-60 199.4 256.4 4.1e-07 29.6 34.3 8.7 1 1 7 8 8 8 7 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CDS34906.1 - 2.1e-26 91.4 88.5 5.1e-09 35.7 23.6 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) C2 PF00168.30 CDS34911.2 - 3.3e-31 107.6 0.1 2.7e-19 69.4 0.0 3.3 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.10 CDS34911.2 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 CDS34911.2 - 0.0015 18.0 1.2 0.006 16.0 0.2 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF639) 2OG-FeII_Oxy_4 PF13661.6 CDS34911.2 - 0.021 15.5 0.1 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily C2 PF00168.30 CDS34912.2 - 4.8e-14 52.5 0.0 4.8e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 CDS34914.2 - 5e-13 49.2 0.1 5.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 CDS34915.2 - 3.8e-26 91.4 0.0 1.2e-09 38.4 0.0 3.4 3 0 0 3 3 3 3 C2 domain Peptidase_M57 PF12388.8 CDS34915.2 - 0.1 12.2 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase PLAC8 PF04749.17 CDS34917.1 - 2.4e-13 50.9 8.2 3.7e-13 50.3 8.2 1.3 1 0 0 1 1 1 1 PLAC8 family HPD PF05044.12 CDS34918.1 - 1.2e-75 252.6 3.3 2.1e-75 251.8 3.3 1.4 1 0 0 1 1 1 1 Homeo-prospero domain DUF1905 PF08922.11 CDS34918.1 - 0.091 12.8 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) Actin PF00022.19 CDS34919.1 - 3.9e-151 503.3 0.0 1.3e-150 501.6 0.0 1.6 1 1 0 1 1 1 1 Actin PLAC8 PF04749.17 CDS34920.1 - 2.4e-13 50.9 8.2 3.7e-13 50.3 8.2 1.3 1 0 0 1 1 1 1 PLAC8 family Actin PF00022.19 CDS34922.1 - 3.9e-151 503.3 0.0 1.3e-150 501.6 0.0 1.6 1 1 0 1 1 1 1 Actin KH_1 PF00013.29 CDS34924.1 - 3.7e-25 87.5 0.4 3.2e-12 46.1 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CDS34924.1 - 4.6e-05 23.2 2.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CDS34924.1 - 0.0047 16.8 0.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 CDS34924.1 - 0.12 12.5 1.0 13 5.9 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain HAT PF02184.16 CDS34925.1 - 0.94 9.5 7.8 12 6.0 0.4 4.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CDS34925.1 - 3.4 8.7 0.0 3.4 8.7 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat CLASP_N PF12348.8 CDS34926.1 - 4.9e-10 39.4 0.0 2e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 CDS34926.1 - 0.015 15.5 0.2 0.34 11.3 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 CDS34926.1 - 0.019 15.5 0.1 2.6 8.7 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Cnd3 PF12719.7 CDS34926.1 - 0.032 13.4 0.2 0.072 12.3 0.2 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain ZT_dimer PF16916.5 CDS34926.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Imm39 PF15568.6 CDS34931.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 1 1 2 2 2 0 Immunity protein 39 ImpA_N PF06812.12 CDS34932.1 - 0.064 13.4 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system PIN_6 PF17146.4 CDS34937.2 - 2.6e-56 188.1 0.3 1.1e-26 93.1 0.0 2.3 2 0 0 2 2 2 2 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CDS34937.2 - 1.3e-24 86.2 1.8 4.3e-21 74.9 0.2 2.4 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like TIP39 PF14980.6 CDS34937.2 - 0.00017 21.4 0.0 0.95 9.4 0.0 2.4 2 0 0 2 2 2 2 TIP39 peptide zinc_ribbon_12 PF11331.8 CDS34937.2 - 0.0016 18.2 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Probable zinc-ribbon domain DUF2616 PF11077.8 CDS34937.2 - 0.17 11.6 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Na_trans_assoc PF06512.13 CDS34937.2 - 0.56 10.5 14.2 3.4 7.9 3.3 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated GAT PF03127.14 CDS34937.2 - 2.3 8.6 7.2 18 5.7 0.8 2.5 2 0 0 2 2 2 0 GAT domain Sec7 PF01369.20 CDS34938.2 - 1.8e-50 171.2 3.1 1.8e-50 171.2 3.1 1.5 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 CDS34938.2 - 2.4e-07 31.2 0.8 5e-07 30.2 0.8 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDS34938.2 - 3.1e-06 27.6 1.3 8.1e-06 26.2 1.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3201 PF11447.8 CDS34938.2 - 0.047 13.2 0.2 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) MFS_2 PF13347.6 CDS34940.1 - 2.7e-40 138.2 6.0 3.3e-40 138.0 6.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CDS34940.1 - 7.7e-05 21.8 2.5 9.6e-05 21.5 2.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDS34941.1 - 1.5e-41 142.4 7.1 1.7e-41 142.2 7.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CDS34941.1 - 2.6e-05 23.3 2.8 3.2e-05 23.0 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Complex1_LYR PF05347.15 CDS34942.1 - 2.6e-12 46.6 0.4 5.6e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDS34942.1 - 0.0021 18.8 0.7 0.0035 18.0 0.7 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Tom37_C PF11801.8 CDS34942.1 - 0.063 13.2 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Sec7 PF01369.20 CDS34943.2 - 6.7e-50 169.3 3.3 6.7e-50 169.3 3.3 1.4 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 CDS34943.2 - 7e-18 65.1 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CDS34943.2 - 1.3e-08 35.2 0.3 4.2e-08 33.6 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PIN_6 PF17146.4 CDS34944.2 - 1.5e-56 188.8 0.3 8.7e-27 93.5 0.0 2.3 2 0 0 2 2 2 2 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CDS34944.2 - 1.9e-21 76.0 0.2 3.3e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like TIP39 PF14980.6 CDS34944.2 - 0.00012 21.9 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 2 TIP39 peptide DUF2616 PF11077.8 CDS34944.2 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DNA_pol_phi PF04931.13 CDS34944.2 - 7.6 4.5 9.8 11 3.9 9.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 CDS34945.2 - 1.6e-05 24.0 4.1 1.9e-05 23.8 4.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q3 PF00499.20 CDS34946.2 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Baculo_11_kDa PF06143.11 CDS34946.2 - 0.39 10.3 3.9 0.5 10.0 0.9 2.2 1 1 1 2 2 2 0 Baculovirus 11 kDa family RhoGEF PF00621.20 CDS34948.2 - 1.2e-07 32.1 0.8 1.2e-07 32.1 0.8 1.9 2 1 0 2 2 2 1 RhoGEF domain Toxin_YhaV PF11663.8 CDS34948.2 - 0.0015 18.6 0.2 0.0056 16.7 0.0 2.0 2 0 0 2 2 2 1 Toxin with endonuclease activity, of toxin-antitoxin system WD40 PF00400.32 CDS34949.2 - 5.3e-54 179.0 20.1 2.9e-08 34.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34949.2 - 4.9e-18 65.2 0.0 0.0095 16.2 0.0 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS34949.2 - 2.7e-08 33.1 0.2 0.068 12.1 0.0 5.1 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS34949.2 - 5.7e-06 26.4 0.1 0.0056 16.6 0.2 3.5 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CDS34949.2 - 2.6e-05 22.7 0.2 0.0049 15.3 0.1 3.2 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 CDS34949.2 - 0.00024 20.6 0.1 0.13 11.6 0.1 2.8 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CDS34949.2 - 0.0035 16.0 3.9 0.13 10.8 0.1 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Peptidase_S37 PF05576.11 CDS34949.2 - 0.043 12.5 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 DUF2415 PF10313.9 CDS34949.2 - 0.045 13.7 0.4 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) F-box-like PF12937.7 CDS34950.1 - 7.3e-14 51.4 1.7 7.3e-14 51.4 1.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDS34950.1 - 9e-13 47.8 2.2 2.3e-12 46.5 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDS34950.1 - 0.013 15.4 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 F-box p25-alpha PF05517.12 CDS34951.2 - 1e-21 77.7 4.0 1.1e-21 77.6 4.0 1.0 1 0 0 1 1 1 1 p25-alpha TPR_2 PF07719.17 CDS34953.1 - 8.3e-14 50.5 1.1 0.0003 20.7 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDS34953.1 - 1.3e-08 34.3 0.0 0.0066 16.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS34953.1 - 2.2e-06 28.0 0.1 0.28 12.1 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDS34953.1 - 5.4e-06 26.2 0.1 0.064 13.5 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDS34953.1 - 0.00011 21.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CDS34953.1 - 0.00063 20.3 0.3 0.033 14.8 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS34953.1 - 0.0015 19.0 0.6 0.012 16.1 0.0 2.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS34953.1 - 0.0016 18.5 0.0 1.3 9.2 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS34953.1 - 0.0081 16.7 4.7 4.3 8.2 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF5357 PF17310.2 CDS34953.1 - 0.02 13.5 0.2 0.13 10.8 0.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5357) ANAPC3 PF12895.7 CDS34953.1 - 0.072 13.3 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CedA PF10729.9 CDS34953.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell division activator CedA Peptidase_S46 PF10459.9 CDS34953.1 - 0.9 8.1 8.9 1.4 7.4 8.9 1.2 1 0 0 1 1 1 0 Peptidase S46 Toxin_YhaV PF11663.8 CDS34955.2 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Toxin with endonuclease activity, of toxin-antitoxin system SH3_9 PF14604.6 CDS34955.2 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain WD40 PF00400.32 CDS34956.1 - 2.1e-53 177.1 20.1 3.5e-08 34.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDS34956.1 - 1.7e-17 63.5 0.0 0.00089 19.5 0.0 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDS34956.1 - 7.1e-08 31.8 0.2 0.071 12.1 0.0 5.0 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDS34956.1 - 1.2e-05 25.3 0.1 0.0075 16.2 0.2 3.5 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CDS34956.1 - 5e-05 21.8 0.2 0.0059 15.0 0.1 3.2 1 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 CDS34956.1 - 0.00036 20.0 0.1 0.17 11.2 0.1 2.9 1 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 CDS34956.1 - 0.0062 15.2 3.9 0.17 10.5 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Peptidase_S37 PF05576.11 CDS34956.1 - 0.051 12.2 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 DUF2415 PF10313.9 CDS34956.1 - 0.066 13.2 0.6 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) TRPM_tetra PF16519.5 CDS34956.1 - 0.14 12.3 0.3 0.25 11.4 0.3 1.4 1 0 0 1 1 1 0 Tetramerisation domain of TRPM F-box-like PF12937.7 CDS34957.1 - 7.3e-14 51.4 1.7 7.3e-14 51.4 1.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDS34957.1 - 9e-13 47.8 2.2 2.3e-12 46.5 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDS34957.1 - 0.013 15.4 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 F-box p25-alpha PF05517.12 CDS34958.2 - 1e-21 77.7 4.0 1.1e-21 77.6 4.0 1.0 1 0 0 1 1 1 1 p25-alpha LAB_N PF07578.11 CDS34960.1 - 0.0024 17.9 0.3 0.0047 17.0 0.3 1.5 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain DUF588 PF04535.12 CDS34960.1 - 0.037 13.8 1.6 0.042 13.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF3165 PF11364.8 CDS34975.1 - 0.59 10.5 5.9 0.86 10.0 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF4302 PF14135.6 CDS34978.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Rrn6 PF10214.9 CDS34979.1 - 0.46 8.9 6.2 0.49 8.8 6.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BET PF17035.5 CDS34980.2 - 7.3e-16 58.1 2.1 1.9e-05 24.7 0.2 3.6 3 0 0 3 3 3 3 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CDS34980.2 - 1.5e-05 24.9 0.0 4.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 CDS34981.2 - 7.2e-41 138.1 0.0 4.5e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CDS34981.2 - 2.7e-28 97.9 0.2 1.1e-27 96.0 0.2 2.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation STI1 PF17830.1 CDS34981.2 - 0.014 15.3 0.2 0.051 13.5 0.1 1.9 2 0 0 2 2 2 0 STI1 domain PRTP PF01366.18 CDS34981.2 - 1.3 7.0 6.3 2.5 6.0 6.3 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein EIF4E-T PF10477.9 CDS34982.2 - 0.0012 17.8 2.4 0.0016 17.4 2.4 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E BEN PF10523.9 CDS34983.2 - 0.041 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 BEN domain Rrn6 PF10214.9 CDS34984.1 - 0.46 8.9 6.2 0.49 8.8 6.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BET PF17035.5 CDS34985.2 - 7.3e-16 58.1 2.1 1.9e-05 24.7 0.2 3.6 3 0 0 3 3 3 3 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CDS34985.2 - 1.5e-05 24.9 0.0 4.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain HLH PF00010.26 CDS34986.2 - 1.1e-13 50.8 1.3 2.9e-13 49.5 1.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Bromodomain PF00439.25 CDS34988.1 - 5.6e-41 138.5 0.0 4e-21 74.9 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CDS34988.1 - 2.9e-28 97.8 0.6 9.4e-28 96.2 0.2 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation STI1 PF17830.1 CDS34988.1 - 0.012 15.5 0.2 0.046 13.7 0.1 2.0 2 0 0 2 2 2 0 STI1 domain PRTP PF01366.18 CDS34988.1 - 1.1 7.2 6.3 2.2 6.2 6.3 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Presenilin PF01080.17 CDS34988.1 - 8.7 5.0 8.5 0.46 9.2 1.7 2.1 2 0 0 2 2 2 0 Presenilin EIF4E-T PF10477.9 CDS34989.1 - 0.0012 17.8 2.4 0.0016 17.4 2.4 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E BEN PF10523.9 CDS34990.1 - 0.041 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 BEN domain Lyase_1 PF00206.20 CDS34996.1 - 1.8e-21 76.9 0.0 3.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CDS34996.1 - 7.6e-14 52.0 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 CDS34997.1 - 1.8e-21 76.9 0.0 3.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CDS34997.1 - 7.6e-14 52.0 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Ank_2 PF12796.7 CDS34999.2 - 1.6e-31 108.7 0.1 3.8e-12 46.6 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS34999.2 - 3.2e-17 62.7 0.0 0.00014 22.3 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS34999.2 - 9.5e-16 57.7 0.7 6.2e-05 23.2 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CDS34999.2 - 1e-15 57.4 7.5 0.0005 20.4 0.1 5.9 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CDS34999.2 - 4.2e-14 51.3 4.0 0.0077 16.7 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Tetraspanin PF00335.20 CDS35003.2 - 6.2e-55 186.4 21.0 1.1e-42 146.3 7.5 2.0 1 1 1 2 2 2 2 Tetraspanin family SUR7 PF06687.12 CDS35003.2 - 0.0027 17.4 19.4 0.15 11.7 5.4 3.1 2 1 0 3 3 3 3 SUR7/PalI family DUF2892 PF11127.8 CDS35003.2 - 3.7 7.7 8.5 2 8.5 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF2981 PF11200.8 CDS35003.2 - 7.3 6.2 15.4 1.4 8.6 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) UQ_con PF00179.26 CDS35005.1 - 2.1e-49 166.8 0.0 2.3e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS35005.1 - 0.0029 17.3 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDS35005.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain BPL_LplA_LipB PF03099.19 CDS35006.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Ank_4 PF13637.6 CDS35011.1 - 7.7e-28 96.5 0.5 1.3e-10 41.6 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS35011.1 - 2.6e-27 95.2 0.4 2.5e-09 37.6 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS35011.1 - 1.9e-22 76.9 2.6 0.0086 16.5 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDS35011.1 - 1.5e-15 56.8 3.8 0.0096 16.3 0.2 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDS35011.1 - 5.2e-15 55.3 4.7 0.00073 19.8 0.1 4.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Hid1 PF12722.7 CDS35011.1 - 1.5 6.8 6.6 0.86 7.6 3.2 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PIEZO PF15917.5 CDS35011.1 - 2.3 7.6 7.3 3.6 7.0 7.3 1.3 1 0 0 1 1 1 0 Piezo RP-C_C PF11800.8 CDS35011.1 - 6.1 6.9 11.5 11 6.1 11.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Sushi PF00084.20 CDS35012.2 - 5.7e-12 46.0 15.8 9.6e-05 22.9 0.1 4.6 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) Sushi PF00084.20 CDS35013.2 - 5.7e-12 46.0 15.8 9.6e-05 22.9 0.1 4.6 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) Ank_4 PF13637.6 CDS35014.1 - 7.7e-28 96.5 0.5 1.3e-10 41.6 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDS35014.1 - 2.6e-27 95.2 0.4 2.5e-09 37.6 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDS35014.1 - 1.9e-22 76.9 2.6 0.0086 16.5 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 CDS35014.1 - 1.5e-15 56.8 3.8 0.0096 16.3 0.2 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CDS35014.1 - 5.2e-15 55.3 4.7 0.00073 19.8 0.1 4.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Hid1 PF12722.7 CDS35014.1 - 1.5 6.8 6.6 0.86 7.6 3.2 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PIEZO PF15917.5 CDS35014.1 - 2.3 7.6 7.3 3.6 7.0 7.3 1.3 1 0 0 1 1 1 0 Piezo RP-C_C PF11800.8 CDS35014.1 - 6.1 6.9 11.5 11 6.1 11.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RRM_5 PF13893.6 CDS35017.2 - 3.6e-37 126.7 0.1 6.2e-20 71.1 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDS35017.2 - 6.9e-19 67.4 0.0 9.3e-07 28.6 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDS35017.2 - 3.5e-12 46.4 0.0 2.8e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 CDS35017.2 - 6.7e-06 25.9 0.1 0.012 15.5 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CDS35017.2 - 0.0018 18.3 0.1 3.3 7.8 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 RL PF17797.1 CDS35017.2 - 0.011 15.6 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 0 RL domain RRM_3 PF08777.11 CDS35017.2 - 0.011 15.7 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif DUF3853 PF12964.7 CDS35017.2 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) RRM_5 PF13893.6 CDS35018.2 - 3.6e-37 126.7 0.1 6.2e-20 71.1 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CDS35018.2 - 6.9e-19 67.4 0.0 9.3e-07 28.6 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CDS35018.2 - 3.5e-12 46.4 0.0 2.8e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 CDS35018.2 - 6.7e-06 25.9 0.1 0.012 15.5 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CDS35018.2 - 0.0018 18.3 0.1 3.3 7.8 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 RL PF17797.1 CDS35018.2 - 0.011 15.6 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 0 RL domain RRM_3 PF08777.11 CDS35018.2 - 0.011 15.7 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif DUF3853 PF12964.7 CDS35018.2 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) TMEM144 PF07857.12 CDS35022.1 - 1.2e-103 346.7 19.7 1.3e-103 346.5 19.7 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CDS35022.1 - 3.3e-14 52.9 17.0 1.8e-10 40.7 9.8 2.8 2 1 0 2 2 2 2 Sugar transport protein EamA PF00892.20 CDS35022.1 - 0.0011 19.1 14.7 0.0011 19.1 14.7 3.1 2 2 0 2 2 2 1 EamA-like transporter family DNA_pol_D_N PF18018.1 CDS35024.1 - 2.4e-25 89.1 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CDS35024.1 - 2.1e-24 86.0 0.0 3.2e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B LicD PF04991.13 CDS35025.1 - 3.8e-12 46.8 1.0 5.3e-09 36.6 0.4 2.3 1 1 1 2 2 2 2 LicD family Defensin_1 PF00323.19 CDS35025.1 - 0.053 14.1 3.6 0.12 12.9 3.6 1.6 1 0 0 1 1 1 0 Mammalian defensin MIB_HERC2 PF06701.13 CDS35026.1 - 2.8e-37 126.8 6.2 4.1e-19 68.6 0.1 2.5 2 1 0 2 2 2 2 Mib_herc2 ZZ PF00569.17 CDS35026.1 - 3.7e-08 33.1 7.5 7.4e-08 32.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type GCV_H PF01597.19 CDS35027.1 - 4.1e-36 123.6 0.1 4.9e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CDS35027.1 - 5.7e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 CDS35027.1 - 0.00062 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 CDS35027.1 - 0.1 12.4 0.3 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like Peptidase_M23 PF01551.22 CDS35027.1 - 0.14 12.4 0.0 1.1 9.5 0.0 2.1 1 1 1 2 2 2 0 Peptidase family M23 Malic_M PF03949.15 CDS35028.1 - 8.4e-81 271.0 0.3 1.1e-80 270.7 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDS35028.1 - 1e-70 237.3 0.0 1.7e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MIB_HERC2 PF06701.13 CDS35030.1 - 3.3e-35 120.2 9.1 3.2e-18 65.7 0.6 2.8 2 0 0 2 2 2 2 Mib_herc2 Ank_2 PF12796.7 CDS35030.1 - 2.6e-17 63.2 1.7 5.4e-13 49.3 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS35030.1 - 1.1e-14 54.6 3.9 3.8e-11 43.3 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDS35030.1 - 1.9e-13 50.3 4.2 2.9e-08 33.8 1.4 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS35030.1 - 5.1e-11 41.8 1.9 6.7e-05 23.0 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDS35030.1 - 2.2e-09 37.4 2.9 7.4e-05 23.0 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat ZZ PF00569.17 CDS35030.1 - 2.4e-07 30.5 8.3 4.7e-07 29.5 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type ANTH PF07651.16 CDS35032.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 ANTH domain SecE PF00584.20 CDS35034.1 - 0.16 11.9 0.5 0.23 11.4 0.5 1.2 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF5336 PF17270.2 CDS35037.1 - 0.14 11.8 1.6 0.31 10.7 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5336) DUF2653 PF10850.8 CDS35042.1 - 0.039 14.1 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) UQ_con PF00179.26 CDS35043.1 - 2.7e-35 121.1 0.1 3.1e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDS35043.1 - 0.0013 18.5 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDS35043.1 - 0.021 15.1 1.0 0.027 14.8 1.0 1.4 1 1 0 1 1 1 0 RWD domain RtcB PF01139.17 CDS35044.2 - 8.1e-148 493.0 0.0 9.1e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB FIST_C PF10442.9 CDS35044.2 - 0.072 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 FIST C domain RVT_1 PF00078.27 CDS35048.1 - 2.4e-14 53.4 0.0 8.3e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3855 PF12967.7 CDS35048.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) RT_RNaseH_2 PF17919.1 CDS35052.1 - 2e-14 53.4 0.1 2.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS35052.1 - 6.6e-08 32.8 0.1 1.3e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDS35053.1 - 2.4e-14 53.4 0.0 8.3e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3855 PF12967.7 CDS35053.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) Bacillus_HBL PF05791.11 CDS35054.2 - 0.031 14.1 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Pox_Ag35 PF03286.14 CDS35056.1 - 1.1 9.0 11.9 1.6 8.5 11.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HTH_48 PF17906.1 CDS35058.1 - 0.00027 21.0 0.2 0.00068 19.7 0.2 1.7 1 0 0 1 1 1 1 HTH domain in Mos1 transposase HTH_24 PF13412.6 CDS35058.1 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 CDS35058.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 CDS35058.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_3 PF01381.22 CDS35058.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix YdaS_antitoxin PF15943.5 CDS35058.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 CDS35058.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 CDS35058.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 CDS35058.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 HTH DNA binding domain MarR_2 PF12802.7 CDS35058.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 MarR family Dcc1 PF09724.9 CDS35058.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Peptidase_M24 PF00557.24 CDS35060.2 - 2.3e-42 145.1 0.2 3.2e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 cNMP_binding PF00027.29 CDS35062.2 - 8.2e-18 64.3 0.1 1.2e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DAP PF15228.6 CDS35064.2 - 0.46 11.7 3.0 0.33 12.1 0.6 2.0 2 0 0 2 2 2 0 Death-associated protein DUF4402 PF14352.6 CDS35064.2 - 1.1 10.0 4.7 2 9.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) AROS PF15684.5 CDS35067.1 - 0.077 13.6 0.1 0.084 13.4 0.1 1.1 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 TORC_M PF12885.7 CDS35070.2 - 0.16 11.9 1.3 0.44 10.5 1.0 1.8 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain DUF2568 PF10823.8 CDS35070.2 - 3.7 7.9 11.0 0.79 10.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Usp PF00582.26 CDS35071.1 - 7.5e-25 88.1 0.0 1.1e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Pkinase_Tyr PF07714.17 CDS35072.2 - 5e-45 153.8 0.0 7.9e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDS35072.2 - 6.4e-23 81.5 0.0 8.3e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ribosomal_L11_N PF03946.14 CDS35072.2 - 5.5e-22 77.4 0.4 9.8e-22 76.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDS35072.2 - 3.5e-15 56.3 0.0 6.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain APH PF01636.23 CDS35072.2 - 0.16 11.9 0.5 4.3 7.2 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nodulin-like PF06813.13 CDS35080.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulin-like Tetraspanin PF00335.20 CDS35086.1 - 0.26 11.0 11.3 0.33 10.6 11.3 1.1 1 0 0 1 1 1 0 Tetraspanin family Sushi PF00084.20 CDS35087.2 - 9.8e-09 35.7 16.6 7.9e-06 26.4 0.6 4.9 4 1 1 5 5 5 2 Sushi repeat (SCR repeat) LapA_dom PF06305.11 CDS35087.2 - 0.39 10.6 2.4 0.7 9.8 2.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Sushi PF00084.20 CDS35088.2 - 0.02 15.5 10.6 0.28 11.8 2.2 4.2 3 1 1 4 4 4 0 Sushi repeat (SCR repeat) CAP PF00188.26 CDS35090.1 - 3.2e-14 53.9 1.5 4.4e-14 53.4 1.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AXH PF08517.12 CDS35091.1 - 0.024 15.2 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) CAP PF00188.26 CDS35092.2 - 3.2e-14 53.9 1.5 4.4e-14 53.4 1.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family AXH PF08517.12 CDS35093.1 - 0.024 15.2 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Cadherin PF00028.17 CDS35094.2 - 5.3e-59 196.7 5.8 5.9e-13 49.1 0.5 9.3 7 3 0 7 7 7 6 Cadherin domain Cadherin_3 PF16184.5 CDS35094.2 - 6.4e-09 35.8 7.3 0.031 14.3 0.1 4.9 6 0 0 6 6 6 3 Cadherin-like Cadherin_2 PF08266.12 CDS35094.2 - 1.5e-07 31.1 3.7 0.00077 19.2 0.1 5.1 5 1 0 5 5 5 2 Cadherin-like Cadherin_pro PF08758.11 CDS35094.2 - 0.00055 20.1 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 Cadherin prodomain like WD40 PF00400.32 CDS35097.1 - 0.0017 19.1 4.7 0.77 10.7 0.9 3.7 3 1 0 3 3 3 3 WD domain, G-beta repeat zf-C2H2 PF00096.26 CDS35099.1 - 7.5e-08 32.4 12.0 0.00061 20.1 4.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS35099.1 - 1.2e-06 28.6 8.5 0.0032 17.8 0.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDS35099.1 - 0.0012 19.5 3.0 0.0012 19.5 3.0 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDS35099.1 - 0.0089 16.0 2.4 0.0089 16.0 2.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger PyrI_C PF02748.15 CDS35099.1 - 0.0092 15.9 5.6 0.069 13.1 0.1 2.6 2 1 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 CDS35099.1 - 0.12 12.6 9.1 0.2 12.0 4.8 2.2 1 1 0 2 2 2 0 C2H2-type zinc ribbon zf-AN1 PF01428.16 CDS35099.1 - 0.13 12.5 7.8 2.3 8.5 1.5 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger Zn_ribbon_SprT PF17283.2 CDS35099.1 - 0.17 11.8 7.7 1.4 8.9 0.8 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 CDS35099.1 - 0.55 10.2 6.7 9.2 6.3 0.7 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF2757 PF10955.8 CDS35099.1 - 2.1 8.7 5.4 2.3 8.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Zn-ribbon_8 PF09723.10 CDS35099.1 - 2.9 8.1 11.1 8.7 6.6 7.7 2.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 CDS35099.1 - 9.6 6.1 15.3 0.5 10.2 3.6 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type NAD_Gly3P_dh_C PF07479.14 CDS35103.1 - 1.7e-08 34.9 0.3 2.7e-08 34.2 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Ras PF00071.22 CDS35112.1 - 1.7e-18 66.7 0.0 1.9e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS35112.1 - 2.9e-05 24.3 0.0 3.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDS35113.2 - 1.1e-65 220.1 1.2 1.3e-65 219.9 1.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDS35113.2 - 3.7e-34 117.5 0.2 6.1e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDS35113.2 - 3.1e-17 62.6 0.3 3.5e-17 62.4 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDS35113.2 - 2.3e-07 30.8 0.2 0.0089 15.9 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CDS35113.2 - 8.1e-07 28.6 0.7 1.3e-06 28.0 0.7 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDS35113.2 - 5.5e-06 26.4 0.1 1.2e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDS35113.2 - 1.8e-05 24.4 0.4 4.7e-05 23.0 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDS35113.2 - 6.3e-05 22.5 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDS35113.2 - 0.0044 17.4 0.0 0.0065 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 CDS35113.2 - 0.0079 15.5 0.7 0.013 14.8 0.1 1.6 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 CDS35113.2 - 0.0082 15.9 0.2 0.016 15.0 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CDS35113.2 - 0.011 16.0 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDS35113.2 - 0.016 14.9 0.8 0.032 13.9 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CDS35113.2 - 0.022 15.2 0.2 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDS35113.2 - 0.029 13.9 0.0 0.058 12.9 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region F-112 PF09645.10 CDS35113.2 - 0.029 14.4 0.2 0.045 13.9 0.2 1.3 1 0 0 1 1 1 0 F-112 protein FeoB_N PF02421.18 CDS35113.2 - 0.031 13.8 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 CDS35113.2 - 0.046 13.4 0.9 0.055 13.2 0.9 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribonucleas_3_2 PF11469.8 CDS35113.2 - 0.055 13.9 0.1 0.077 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease III AAA_14 PF13173.6 CDS35113.2 - 0.091 12.8 0.5 0.32 11.0 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 CDS35113.2 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavodoxin_1 PF00258.25 CDS35114.2 - 6.3e-19 68.6 0.0 1.4e-18 67.5 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CDS35114.2 - 2.7e-12 46.7 0.0 5.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Exo_endo_phos_2 PF14529.6 CDS35117.1 - 0.00055 19.8 0.1 0.001 18.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDS35117.1 - 0.093 12.2 0.0 0.097 12.2 0.0 1.3 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family L27 PF02828.16 CDS35119.1 - 0.015 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 L27 domain TPR_2 PF07719.17 CDS35120.1 - 3e-24 83.1 16.7 8.5e-05 22.4 0.3 10.4 11 1 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CDS35120.1 - 3e-23 80.6 9.5 3.3e-05 23.5 0.8 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDS35120.1 - 8.9e-23 78.6 4.6 0.0018 18.3 0.2 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CDS35120.1 - 9.6e-20 70.6 19.6 5.6e-14 52.1 3.5 5.2 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDS35120.1 - 1.3e-18 66.4 0.0 0.00037 20.1 0.0 5.7 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.6 CDS35120.1 - 3e-16 59.7 7.4 0.00029 21.3 0.0 7.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDS35120.1 - 8.8e-11 41.4 7.4 0.0014 18.9 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDS35120.1 - 1.2e-10 41.3 12.0 2.2 9.3 0.0 9.1 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDS35120.1 - 6.8e-10 39.1 12.1 0.0016 18.7 0.0 6.4 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDS35120.1 - 9.3e-09 35.8 10.2 0.00094 19.8 1.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDS35120.1 - 5.2e-07 29.3 6.9 0.1 12.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDS35120.1 - 5.3e-06 26.5 0.8 0.0023 18.0 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDS35120.1 - 0.00028 21.3 8.1 53 4.8 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CDS35120.1 - 0.014 15.4 0.2 0.46 10.5 0.0 3.1 3 1 0 3 3 3 0 Putative TPR-like repeat TPR_20 PF14561.6 CDS35120.1 - 0.028 14.7 0.2 4.8 7.6 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 CDS35120.1 - 0.17 10.5 0.0 0.87 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 CDS35120.1 - 0.37 10.1 3.3 69 2.7 0.2 3.8 3 2 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 CDS35120.1 - 0.67 9.9 11.7 11 6.0 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat EF-hand_10 PF14788.6 CDS35122.1 - 0.12 12.2 1.1 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 EF hand CBS PF00571.28 CDS35123.2 - 1.4e-18 67.0 0.0 5.4e-06 26.8 0.1 6.0 5 1 1 6 6 6 4 CBS domain Tub_N PF16322.5 CDS35123.2 - 1.3 9.4 47.6 0.052 14.0 7.2 3.4 3 0 0 3 3 3 0 Tubby N-terminal Pkinase_Tyr PF07714.17 CDS35124.1 - 9.8e-36 123.4 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 CDS35124.1 - 2.6e-23 81.9 0.5 4.9e-23 81.0 0.5 1.5 1 0 0 1 1 1 1 SH2 domain Pkinase PF00069.25 CDS35124.1 - 7.5e-21 74.7 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH3_2 PF07653.17 CDS35124.1 - 6.6e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDS35124.1 - 1.4e-05 24.6 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDS35124.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2322 PF10084.9 CDS35124.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Cadherin PF00028.17 CDS35127.2 - 1.4e-43 147.2 0.2 1.3e-09 38.4 0.0 6.3 6 1 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CDS35127.2 - 1.6e-13 50.3 0.2 3.6e-10 39.5 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CDS35127.2 - 1.4e-05 25.0 3.4 5.5 7.0 0.0 4.8 4 0 0 4 4 4 4 Cadherin-like Cadherin PF00028.17 CDS35128.2 - 1.4e-43 147.2 0.2 1.3e-09 38.4 0.0 6.3 6 1 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CDS35128.2 - 1.6e-13 50.3 0.2 3.6e-10 39.5 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CDS35128.2 - 1.4e-05 25.0 3.4 5.5 7.0 0.0 4.8 4 0 0 4 4 4 4 Cadherin-like Methyltransf_31 PF13847.6 CDS35131.1 - 3.2e-19 69.2 0.0 4.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDS35131.1 - 1.1e-11 45.3 0.0 3.8e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDS35131.1 - 5.9e-11 42.5 0.0 1.6e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDS35131.1 - 3.7e-10 40.3 0.0 7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDS35131.1 - 3.5e-09 37.3 0.0 6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CDS35131.1 - 3e-07 30.3 0.0 7.1e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 CDS35131.1 - 2.5e-06 27.1 0.0 7.4e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 CDS35131.1 - 4.3e-06 26.3 0.1 7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_20 PF12147.8 CDS35131.1 - 8.7e-05 21.8 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 CDS35131.1 - 0.00028 20.9 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDS35131.1 - 0.00094 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CDS35131.1 - 0.0019 18.1 0.0 0.011 15.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CDS35131.1 - 0.003 16.9 0.1 0.0084 15.4 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 CDS35131.1 - 0.004 16.7 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 CDS35131.1 - 0.0045 15.9 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 CDS35131.1 - 0.051 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 CDS35131.1 - 0.055 12.4 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MetW PF07021.12 CDS35131.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 CDS35131.1 - 0.068 12.3 0.1 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 mRNA capping enzyme Cons_hypoth95 PF03602.15 CDS35131.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Reprolysin_5 PF13688.6 CDS35132.1 - 0.021 15.0 2.2 0.022 14.9 0.2 1.9 2 1 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin PF01421.19 CDS35132.1 - 0.15 11.9 1.8 0.22 11.4 1.8 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease DEAD PF00270.29 CDS35135.1 - 1.3e-40 139.0 0.0 2.2e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS35135.1 - 7.6e-29 100.3 0.0 2e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS35135.1 - 0.0024 17.9 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_1 PF01344.25 CDS35137.2 - 8.4e-09 34.9 0.1 1.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CDS35137.2 - 4.8e-07 29.6 0.1 9.8e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 CDS35137.2 - 0.00017 21.7 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CDS35137.2 - 0.00088 19.2 0.1 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CDS35137.2 - 0.061 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.6 CDS35137.2 - 0.11 12.8 0.0 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain SCF PF02404.15 CDS35138.1 - 0.079 12.3 0.6 0.086 12.2 0.6 1.0 1 0 0 1 1 1 0 Stem cell factor SCF PF02404.15 CDS35142.1 - 0.079 12.3 0.6 0.086 12.2 0.6 1.0 1 0 0 1 1 1 0 Stem cell factor RVT_1 PF00078.27 CDS35145.1 - 5.5e-06 26.0 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SwrA PF17423.2 CDS35148.1 - 0.0097 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Swarming motility protein Tricorn_C1 PF14684.6 CDS35155.1 - 0.039 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain SNF2_N PF00176.23 CDS35158.1 - 2.2e-62 210.8 0.0 5.1e-62 209.6 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CDS35158.1 - 4.6e-22 77.7 6.8 1.3e-11 44.2 0.4 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CDS35158.1 - 1.6e-19 70.2 0.0 7.4e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 CDS35158.1 - 1.9e-14 53.8 0.3 9.7e-14 51.6 0.3 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) CDH1_2_SANT_HL1 PF18375.1 CDS35158.1 - 2.8e-11 43.9 2.3 2.2e-10 41.1 0.0 3.5 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ResIII PF04851.15 CDS35158.1 - 7e-09 35.9 0.0 5.8e-08 32.9 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FERM_F2 PF18377.1 CDS35158.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain SLIDE PF09111.10 CDS35158.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 SLIDE CHDCT2 PF08074.11 CDS35158.1 - 0.28 11.4 2.9 0.69 10.1 0.0 3.2 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain RhoGEF PF00621.20 CDS35160.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain Ank_2 PF12796.7 CDS35166.1 - 2.5e-48 162.6 1.0 1.3e-10 41.7 0.0 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDS35166.1 - 1.5e-37 127.2 12.2 8.2e-08 32.4 0.2 8.0 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDS35166.1 - 2.9e-34 117.0 10.9 5.2e-09 36.5 0.1 7.0 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS35166.1 - 1.6e-33 111.0 8.4 0.00072 19.8 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 CDS35166.1 - 6e-30 102.4 20.6 4.7e-05 23.6 0.2 9.4 10 0 0 10 10 10 8 Ankyrin repeat T2SSF PF00482.23 CDS35166.1 - 0.02 14.9 0.3 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Ad_Cy_reg PF16701.5 CDS35166.1 - 0.037 13.8 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain ATP-synt_B PF00430.18 CDS35166.1 - 3.7 7.7 5.9 25 5.0 0.6 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Vmethyltransf PF01660.17 CDS35168.1 - 0.029 13.3 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Viral methyltransferase DUF658 PF04936.12 CDS35169.1 - 0.21 11.3 0.2 0.35 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) RCC1 PF00415.18 CDS35173.2 - 3.8e-46 155.5 16.1 3.7e-06 27.5 0.0 9.5 9 0 0 9 9 9 9 Regulator of chromosome condensation (RCC1) repeat DnaJ PF00226.31 CDS35173.2 - 1.2e-35 121.4 0.8 2.1e-16 59.8 0.1 2.6 2 0 0 2 2 2 2 DnaJ domain RCC1_2 PF13540.6 CDS35173.2 - 1e-15 57.1 30.7 1.4e-07 31.1 0.6 8.3 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Arm-DNA-bind_1 PF09003.10 CDS35173.2 - 0.0053 16.9 0.0 6.9 6.9 0.0 2.7 2 0 0 2 2 2 2 Bacteriophage lambda integrase, Arm DNA-binding domain DUF5537 PF17690.1 CDS35173.2 - 0.013 15.2 0.9 20 4.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5537) zf-C2HC_2 PF13913.6 CDS35173.2 - 0.13 12.2 1.9 18 5.4 0.1 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 CDS35173.2 - 0.19 12.5 1.5 37 5.2 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon family Exo_endo_phos_2 PF14529.6 CDS35174.1 - 5e-06 26.4 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-C2H2_4 PF13894.6 CDS35176.1 - 2.4e-35 118.1 37.4 3.1e-05 24.4 0.7 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CDS35176.1 - 2.4e-34 115.8 35.9 2.2e-07 30.9 0.3 7.2 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDS35176.1 - 1.1e-29 101.5 33.0 8.2e-06 26.0 0.1 7.8 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2_11 PF16622.5 CDS35176.1 - 1.7e-24 85.3 23.7 0.0013 18.4 0.6 7.1 7 0 0 7 7 7 6 zinc-finger C2H2-type zf-met PF12874.7 CDS35176.1 - 6e-23 80.5 18.2 1.1e-05 25.6 0.0 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDS35176.1 - 7.2e-22 77.1 20.0 3.2e-05 24.1 0.1 7.3 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDS35176.1 - 8.9e-15 54.3 40.4 0.0059 16.6 0.9 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CDS35176.1 - 6.5e-11 43.0 18.2 0.0031 18.2 0.5 5.0 1 1 4 6 6 6 5 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 CDS35176.1 - 8.4e-09 35.3 16.4 0.048 13.7 0.0 5.6 4 2 2 6 6 5 4 BED zinc finger zf-Di19 PF05605.12 CDS35176.1 - 1.2e-08 35.1 22.2 0.025 14.9 1.0 5.5 4 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding DUF4764 PF15961.5 CDS35176.1 - 5.7e-08 32.0 13.9 0.00043 19.1 1.0 4.4 3 1 0 4 4 4 3 Domain of unknown function (DUF4764) zf-C2H2_2 PF12756.7 CDS35176.1 - 5.4e-07 29.9 21.0 1.4 9.3 0.1 6.5 1 1 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CDS35176.1 - 2.7e-06 27.0 39.5 0.037 13.8 0.0 7.5 8 1 0 8 8 6 3 C2H2-type zinc-finger domain zf_UBZ PF18439.1 CDS35176.1 - 6.5e-06 25.6 24.4 0.49 10.0 0.2 7.1 7 0 0 7 7 7 3 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 CDS35176.1 - 1.2e-05 25.3 22.7 5.1 7.3 0.1 7.1 7 0 0 7 7 7 0 AN1-like Zinc finger PyrI_C PF02748.15 CDS35176.1 - 5.1e-05 23.1 14.7 2.4 8.1 0.1 6.2 5 1 1 6 6 6 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_12 PF18658.1 CDS35176.1 - 0.00016 21.2 15.6 0.12 11.9 0.1 4.9 1 1 2 4 4 4 2 Zinc-finger C2H2-type SIR2 PF02146.17 CDS35176.1 - 0.00025 21.0 11.6 0.37 10.7 0.2 3.9 1 1 2 3 3 3 2 Sir2 family LIM PF00412.22 CDS35176.1 - 0.00095 19.3 28.4 4.3 7.6 3.5 6.5 2 1 5 7 7 7 0 LIM domain Baculo_IE-1 PF05290.11 CDS35176.1 - 0.0011 18.9 10.5 1.5 8.8 0.2 4.7 1 1 2 4 4 4 1 Baculovirus immediate-early protein (IE-0) zf-C2HE PF16278.5 CDS35176.1 - 0.0021 18.5 29.0 3.3 8.2 0.1 6.9 1 1 6 7 7 7 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 CDS35176.1 - 0.0023 18.2 18.9 0.47 10.8 1.2 4.0 1 1 3 4 4 4 2 C2H2-type zinc ribbon DUF629 PF04780.12 CDS35176.1 - 0.0027 16.3 25.6 0.21 10.0 0.2 6.2 1 1 6 7 7 7 2 Protein of unknown function (DUF629) Sec34 PF04136.15 CDS35176.1 - 0.0043 16.9 0.3 0.8 9.6 0.1 2.9 1 1 3 4 4 4 2 Sec34-like family BolA PF01722.18 CDS35176.1 - 0.0058 16.9 5.1 2.8 8.3 0.5 4.0 2 1 2 4 4 4 1 BolA-like protein ADK_lid PF05191.14 CDS35176.1 - 0.013 15.5 12.6 14 5.7 0.0 5.4 2 1 2 4 4 4 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.6 CDS35176.1 - 0.013 15.4 33.7 0.059 13.3 0.5 7.7 7 1 0 7 7 7 0 zinc-finger of a C2HC-type zf_C2H2_10 PF18414.1 CDS35176.1 - 0.025 14.1 1.2 0.66 9.6 0.0 3.4 4 0 0 4 4 2 0 C2H2 type zinc-finger zinc-ribbons_6 PF07191.12 CDS35176.1 - 0.033 14.2 21.6 4.9 7.2 3.8 4.9 1 1 1 2 2 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 CDS35176.1 - 0.041 14.0 30.0 1.4 9.1 3.3 6.3 3 2 3 6 6 6 0 Zinc ribbon domain CpXC PF14353.6 CDS35176.1 - 0.064 13.3 21.9 2.6 8.1 0.2 6.3 1 1 6 7 7 7 0 CpXC protein zf_Hakai PF18408.1 CDS35176.1 - 0.097 12.4 0.5 0.097 12.4 0.5 4.6 5 0 0 5 5 4 0 C2H2 Hakai zinc finger domain zf-3CxxC PF13695.6 CDS35176.1 - 0.1 13.1 26.9 21 5.7 3.0 4.9 1 1 2 3 3 3 0 Zinc-binding domain Ring_hydroxyl_A PF00848.19 CDS35176.1 - 0.15 12.0 0.8 11 5.9 0.1 2.6 3 0 0 3 3 2 0 Ring hydroxylating alpha subunit (catalytic domain) DUF2256 PF10013.9 CDS35176.1 - 0.24 11.6 22.8 4 7.6 0.2 6.5 4 1 3 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) Desulfoferrod_N PF06397.12 CDS35176.1 - 0.24 11.0 13.7 1.9 8.2 0.0 4.8 5 0 0 5 5 4 0 Desulfoferrodoxin, N-terminal domain zf_PR_Knuckle PF18445.1 CDS35176.1 - 0.29 11.0 9.4 7 6.6 0.1 4.8 6 0 0 6 6 4 0 PR zinc knuckle motif XPA_N PF01286.18 CDS35176.1 - 0.31 11.1 33.6 7.5 6.7 0.3 7.1 7 0 0 7 7 7 0 XPA protein N-terminal Sgf11 PF08209.11 CDS35176.1 - 0.93 9.1 20.9 27 4.4 0.1 6.8 7 0 0 7 7 7 0 Sgf11 (transcriptional regulation protein) FOXP-CC PF16159.5 CDS35176.1 - 1.2 9.8 11.9 73 4.1 0.1 5.7 2 2 4 6 6 6 0 FOXP coiled-coil domain Baculo_RING PF05883.11 CDS35176.1 - 1.3 9.0 6.0 2.3 8.2 0.9 2.9 1 1 1 3 3 3 0 Baculovirus U-box/Ring-like domain zf_C2H2_ZHX PF18387.1 CDS35176.1 - 1.6 8.5 22.1 7.1 6.3 0.1 6.0 2 2 5 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain Ribosomal_L34e PF01199.18 CDS35176.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.1 2 1 0 3 3 3 0 Ribosomal protein L34e CtIP_N PF10482.9 CDS35176.1 - 2.9 8.0 10.2 30 4.7 0.1 4.5 1 1 3 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain VATC PF18716.1 CDS35176.1 - 3.5 7.5 22.8 23 4.9 0.1 6.8 6 1 1 7 7 7 0 Vms1-associating treble clef domain zf-C2H2_9 PF16293.5 CDS35176.1 - 4.3 7.2 7.3 1.1e+02 2.7 0.0 4.6 4 1 2 6 6 6 0 C2H2 type zinc-finger (1 copy) Tox-PL-2 PF15643.6 CDS35176.1 - 6.8 6.9 12.0 5.5 7.2 0.1 4.6 3 2 1 5 5 4 0 Papain fold toxin 2 zf-CCHC_2 PF13696.6 CDS35176.1 - 8.9 6.2 8.2 19 5.2 0.3 3.9 4 0 0 4 4 4 0 Zinc knuckle DUF21 PF01595.20 CDS35177.1 - 3.5e-35 121.3 0.5 6.6e-35 120.4 0.5 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDS35177.1 - 3.4e-06 27.4 0.1 0.00011 22.6 0.0 2.6 2 0 0 2 2 2 1 CBS domain Tweety PF04906.13 CDS35179.1 - 0.021 13.5 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 Tweety SOAR PF16533.5 CDS35179.1 - 0.026 14.5 0.4 0.082 12.9 0.4 1.8 1 1 0 1 1 1 0 STIM1 Orai1-activating region RPA_interact_N PF14766.6 CDS35179.1 - 0.055 13.1 5.8 0.061 13.0 4.5 1.8 1 1 0 1 1 1 0 Replication protein A interacting N-terminal FapA PF03961.13 CDS35179.1 - 0.2 10.2 0.4 0.21 10.2 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snurportin1 PF11538.8 CDS35179.1 - 1.6 8.9 6.0 19 5.5 6.0 2.3 1 1 0 1 1 1 0 Snurportin1 Tweety PF04906.13 CDS35183.1 - 0.021 13.5 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 Tweety SOAR PF16533.5 CDS35183.1 - 0.026 14.5 0.4 0.082 12.9 0.4 1.8 1 1 0 1 1 1 0 STIM1 Orai1-activating region RPA_interact_N PF14766.6 CDS35183.1 - 0.055 13.1 5.8 0.061 13.0 4.5 1.8 1 1 0 1 1 1 0 Replication protein A interacting N-terminal FapA PF03961.13 CDS35183.1 - 0.2 10.2 0.4 0.21 10.2 0.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snurportin1 PF11538.8 CDS35183.1 - 1.6 8.9 6.0 19 5.5 6.0 2.3 1 1 0 1 1 1 0 Snurportin1 TMEM223 PF14640.6 CDS35184.2 - 1.3e-14 54.7 0.1 3e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 223 RRM_1 PF00076.22 CDS35184.2 - 1.5e-11 43.9 0.0 3.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exonuc_VII_S PF02609.16 CDS35184.2 - 0.43 10.7 3.6 0.54 10.4 1.9 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1201 PF06716.11 CDS35184.2 - 1.1 9.4 5.2 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) HLH PF00010.26 CDS35186.1 - 0.014 15.4 0.3 0.031 14.3 0.3 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF3216 PF11505.8 CDS35186.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Cpn60_TCP1 PF00118.24 CDS35192.1 - 1.1e-147 492.6 11.0 1.3e-147 492.4 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EF_assoc_1 PF08355.12 CDS35193.1 - 1.2e-15 56.8 0.1 3.4e-15 55.4 0.1 1.8 1 1 0 1 1 1 1 EF hand associated Ras PF00071.22 CDS35193.1 - 0.086 12.4 0.0 0.34 10.5 0.0 1.8 1 1 0 1 1 1 0 Ras family EcsC PF12787.7 CDS35193.1 - 0.22 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family MFS_1 PF07690.16 CDS35194.1 - 1.1e-21 77.2 29.3 4.2e-18 65.4 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 CDS35194.1 - 0.032 12.5 12.7 0.011 14.0 7.1 2.5 2 1 0 2 2 2 0 BT1 family MS_channel PF00924.18 CDS35194.1 - 0.23 11.0 3.2 0.5 9.9 3.2 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel zf-MYND PF01753.18 CDS35195.1 - 0.15 12.1 8.2 0.32 11.1 8.2 1.5 1 0 0 1 1 1 0 MYND finger SLBP_RNA_bind PF15247.6 CDS35196.2 - 8.5e-23 80.3 4.4 8.5e-23 80.3 4.4 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain RRM_1 PF00076.22 CDS35197.1 - 2.3e-05 24.1 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDS35197.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 RL domain PsaD PF02531.16 CDS35197.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 PsaD Glyco_transf_64 PF09258.10 CDS35199.1 - 8.5e-65 218.4 0.1 1.2e-64 218.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 CDS35199.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Receptor_2B4 PF11465.8 CDS35200.1 - 0.17 12.1 0.2 0.81 9.9 0.0 2.1 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 DUF1935 PF09149.10 CDS35201.1 - 0.002 18.5 0.1 0.0023 18.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C6 PF00851.18 CDS35201.1 - 0.1 11.5 0.1 0.11 11.4 0.1 1.0 1 0 0 1 1 1 0 Helper component proteinase MFS_2 PF13347.6 CDS35206.1 - 3.4e-15 55.5 0.1 3.9e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein zf-C2H2 PF00096.26 CDS35210.2 - 2.1e-21 75.1 28.6 6.6e-06 26.3 2.3 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDS35210.2 - 1.3e-13 50.8 3.6 0.00045 20.4 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDS35210.2 - 1.4e-13 50.4 33.1 4.8e-05 23.8 0.9 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDS35210.2 - 7.3e-12 45.1 31.0 1.9e-06 28.0 0.9 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 CDS35210.2 - 7e-11 42.1 17.9 0.0015 18.9 0.0 5.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDS35210.2 - 2.1e-09 37.1 17.9 0.012 15.6 0.4 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.15 CDS35210.2 - 7.7e-05 22.6 22.1 0.39 10.8 0.4 4.5 1 1 2 3 3 3 2 BED zinc finger zf-C2H2_2 PF12756.7 CDS35210.2 - 0.0055 17.0 16.0 0.029 14.7 1.3 3.9 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Baculo_IE-1 PF05290.11 CDS35210.2 - 0.066 13.2 0.4 0.066 13.2 0.4 2.8 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2HE PF16278.5 CDS35210.2 - 0.34 11.4 21.7 0.3 11.5 0.4 4.5 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 CDS35210.2 - 0.96 9.8 11.7 0.2 12.0 1.4 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CDS35210.2 - 6 6.7 20.7 7.2 6.5 3.7 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_PR_Knuckle PF18445.1 CDS35210.2 - 6.7 6.6 10.5 2.2 8.2 0.1 3.7 4 0 0 4 4 4 0 PR zinc knuckle motif HECT PF00632.25 CDS35213.1 - 8.3e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PDZ PF00595.24 CDS35214.1 - 5.6e-21 74.7 0.2 5.5e-09 36.3 0.0 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 CDS35214.1 - 8.5e-18 64.0 0.0 4e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CDS35214.1 - 2.2e-14 53.5 0.0 0.00011 22.4 0.0 3.5 3 0 0 3 3 3 3 PDZ domain Kin17_mid PF10357.9 CDS35214.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Aminotran_5 PF00266.19 CDS35215.2 - 5.6e-34 117.7 0.0 1.4e-33 116.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDS35215.2 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Cation_efflux PF01545.21 CDS35216.2 - 1.2e-45 155.7 0.0 1.9e-45 155.0 0.0 1.3 1 1 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.21 CDS35217.1 - 5.3e-46 156.9 0.1 1.4e-45 155.5 0.1 1.6 1 1 0 1 1 1 1 Cation efflux family RVT_1 PF00078.27 CDS35223.2 - 2e-07 30.7 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LicD PF04991.13 CDS35224.1 - 3.2e-14 53.6 0.0 6.6e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 LicD family LicD PF04991.13 CDS35225.1 - 3.2e-14 53.6 0.0 6.6e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 LicD family CX PF01705.19 CDS35228.2 - 0.042 14.4 5.8 0.12 12.9 5.8 1.9 1 0 0 1 1 1 0 CX module 7tm_2 PF00002.24 CDS35230.1 - 0.00022 20.6 0.3 0.00042 19.7 0.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srw PF10324.9 CDS35233.1 - 3.3e-27 95.6 12.8 3.9e-15 55.9 6.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CDS35233.1 - 2.4e-11 43.5 6.5 4.5e-11 42.6 6.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CDS35233.1 - 7.5e-06 25.8 6.5 2.1e-05 24.3 6.5 1.8 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pho86 PF11124.8 CDS35233.1 - 2.3 7.6 9.9 0.16 11.4 1.1 2.3 1 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 Ion_trans PF00520.31 CDS35237.1 - 2.6e-18 66.1 0.7 2.8e-18 66.1 0.7 1.0 1 0 0 1 1 1 1 Ion transport protein TraX PF05857.11 CDS35237.1 - 0.0074 16.4 0.8 0.0087 16.1 0.8 1.1 1 0 0 1 1 1 1 TraX protein Baculo_p33 PF05214.12 CDS35237.1 - 0.051 13.3 0.2 0.063 13.0 0.2 1.1 1 0 0 1 1 1 0 Baculovirus P33 ATP_bind_3 PF01171.20 CDS35240.1 - 6.4e-09 35.8 0.1 1.4e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 PP-loop family Peptidase_M22 PF00814.25 CDS35240.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family Dynein_light PF01221.18 CDS35241.1 - 7.8e-24 83.8 0.0 8.6e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PNP_UDP_1 PF01048.20 CDS35244.2 - 4.6e-47 160.2 1.3 5.2e-47 160.1 1.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Mut7-C PF01927.16 CDS35244.2 - 0.12 12.5 0.2 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 Mut7-C RNAse domain TPR_12 PF13424.6 CDS35249.2 - 1.2e-12 47.9 7.0 1.2e-07 31.8 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDS35249.2 - 8.9e-05 23.0 1.6 9.9 7.3 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDS35249.2 - 0.00018 21.3 0.4 12 6.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDS35249.2 - 0.0003 20.7 2.8 12 6.3 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDS35249.2 - 0.0072 16.8 11.4 4.5 7.9 0.1 5.0 3 2 3 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 CDS35249.2 - 0.01 15.9 1.7 0.21 11.7 0.7 3.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 CDS35249.2 - 0.019 15.6 2.0 91 4.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDS35249.2 - 0.45 9.7 0.0 0.45 9.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 CDS35249.2 - 1.5 8.7 6.8 0.4 10.6 0.2 3.0 4 0 0 4 4 4 0 YfdX protein DUF4106 PF13388.6 CDS35252.2 - 1.8 7.7 7.3 2.4 7.3 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1882 PF08966.11 CDS35255.1 - 0.034 14.4 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) GST_N PF02798.20 CDS35256.2 - 1.2e-18 67.1 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDS35256.2 - 2.9e-05 24.4 0.0 9.6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RVT_1 PF00078.27 CDS35257.1 - 5e-15 55.6 0.1 9.2e-15 54.8 0.1 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4821 PF16092.5 CDS35257.1 - 0.029 14.0 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) RT_RNaseH_2 PF17919.1 CDS35258.1 - 2.5e-28 98.0 0.8 4.6e-28 97.2 0.3 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS35258.1 - 1.3e-25 89.7 0.0 2.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDS35258.1 - 1.6e-12 47.7 0.0 5e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 Integrase core domain rve_3 PF13683.6 CDS35258.1 - 0.00039 20.1 0.0 0.00098 18.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Fijivirus_P9-2 PF06837.11 CDS35259.1 - 0.014 14.9 0.1 0.02 14.3 0.1 1.3 1 1 0 1 1 1 0 Fijivirus P9-2 protein ADH_N PF08240.12 CDS35263.1 - 2.5e-13 49.9 1.5 4.8e-13 48.9 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MazE_antitoxin PF04014.18 CDS35263.1 - 0.13 12.2 0.5 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin RT_RNaseH_2 PF17919.1 CDS35270.1 - 8.9e-07 28.9 0.4 5.5e-06 26.3 0.4 2.3 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDS35270.1 - 0.0079 16.5 0.0 0.044 14.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Serpin PF00079.20 CDS35272.1 - 2.7e-13 50.0 0.2 3.9e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) fn3 PF00041.21 CDS35273.1 - 3.9e-13 49.6 0.1 1.3e-07 31.8 0.0 2.7 2 1 0 2 2 2 2 Fibronectin type III domain Interfer-bind PF09294.10 CDS35273.1 - 0.15 12.4 0.3 1.5 9.2 0.0 2.5 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III ESCRT-II PF05871.12 CDS35275.1 - 0.00042 20.6 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 2 1 ESCRT-II complex subunit GntR PF00392.21 CDS35275.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ank_2 PF12796.7 CDS35276.2 - 2.4e-38 130.6 0.2 1.3e-11 44.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS35276.2 - 8.9e-25 86.7 0.2 0.00045 20.7 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDS35276.2 - 2.3e-23 81.5 6.7 0.0065 16.9 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CDS35276.2 - 1.1e-21 74.6 10.0 0.024 15.2 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 CDS35276.2 - 3.1e-19 68.8 7.3 0.00023 21.4 0.2 6.9 3 2 4 7 7 7 5 Ankyrin repeats (many copies) TMEM154 PF15102.6 CDS35277.2 - 0.0046 16.9 0.0 0.0052 16.7 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 CDS35277.2 - 0.023 14.5 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MSP1a PF11670.8 CDS35277.2 - 0.031 13.6 0.4 0.038 13.3 0.4 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3619 PF12279.8 CDS35277.2 - 0.033 14.5 0.1 0.048 14.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4051 PF13260.6 CDS35277.2 - 0.054 13.2 1.2 0.087 12.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Endomucin PF07010.12 CDS35277.2 - 0.058 13.4 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Endomucin LRR19-TM PF15176.6 CDS35277.2 - 0.063 13.3 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2207 PF09972.9 CDS35277.2 - 0.16 10.7 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SK_channel PF03530.14 CDS35278.2 - 1.5e-10 41.0 0.6 2.9e-10 40.1 0.6 1.4 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Brr6_like_C_C PF10104.9 CDS35278.2 - 0.12 12.2 2.4 11 5.8 0.3 2.5 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Brr6_like_C_C PF10104.9 CDS35279.2 - 0.12 12.1 2.6 10 5.9 0.3 2.3 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Parvo_NS1 PF01057.17 CDS35281.1 - 7.2e-06 25.3 0.1 8.3e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 EMG1 PF03587.14 CDS35283.1 - 1e-73 247.2 0.0 1.2e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Phosphodiest PF01663.22 CDS35287.2 - 7.9e-10 38.8 0.3 1.1e-09 38.4 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CDS35287.2 - 1.9e-07 30.7 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDS35287.2 - 3.6e-06 26.6 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF5314 PF17241.2 CDS35287.2 - 0.11 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) MIF4G PF02854.19 CDS35291.1 - 1.3e-14 54.3 10.4 1.5e-14 54.1 6.8 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CDS35291.1 - 2.6e-14 53.1 3.5 8.3e-10 38.7 0.4 3.4 3 1 0 3 3 3 2 MA3 domain SR-25 PF10500.9 CDS35291.1 - 1.5 8.4 11.5 3.1 7.3 11.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NOB1_Zn_bind PF08772.11 CDS35292.1 - 0.0015 18.6 1.4 0.0056 16.8 1.4 1.9 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 CDS35292.1 - 0.0084 15.8 3.6 0.0084 15.8 3.6 3.0 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CDS35292.1 - 0.011 16.4 0.2 0.011 16.4 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbon family HypA PF01155.19 CDS35292.1 - 0.023 14.7 0.2 0.055 13.5 0.2 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CDS35292.1 - 0.025 14.6 0.6 0.025 14.6 0.6 2.5 3 1 0 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CDS35292.1 - 0.031 13.7 2.3 0.1 12.0 2.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 CDS35292.1 - 0.05 13.5 1.5 5.5 7.0 0.5 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 CDS35292.1 - 2.2 8.4 6.4 13 6.0 6.4 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF1005 PF06219.12 CDS35293.2 - 0.048 12.7 0.5 0.078 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) TPR_2 PF07719.17 CDS35298.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS35298.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDS35299.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDS35299.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Sas10_Utp3 PF04000.15 CDS35300.1 - 8.6e-13 48.7 0.2 1.2e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.8 CDS35300.1 - 0.0041 16.0 0.2 0.0051 15.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FdtA PF05523.11 CDS35300.1 - 0.026 14.2 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 WxcM-like, C-terminal PTPA PF03095.15 CDS35300.1 - 0.042 13.3 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Benyvirus_14KDa PF07255.11 CDS35300.1 - 0.12 12.7 0.5 0.77 10.0 0.2 1.9 1 1 1 2 2 2 0 Benyvirus 14KDa protein DEAD PF00270.29 CDS35301.1 - 2.8e-40 138.0 0.7 4.4e-40 137.3 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDS35301.1 - 5.1e-30 104.1 0.2 2.3e-28 98.7 0.0 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDS35301.1 - 6.5e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDS35301.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDS35301.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_polI_A34 PF08208.11 CDS35302.1 - 0.0035 17.5 11.4 0.0035 17.5 11.4 2.4 2 0 0 2 2 1 1 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 CDS35302.1 - 0.0073 16.6 8.9 0.0073 16.6 8.9 2.5 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 DUF4604 PF15377.6 CDS35302.1 - 0.017 15.6 6.6 0.017 15.6 6.6 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4604) DUF3807 PF12720.7 CDS35302.1 - 0.019 15.3 20.7 0.25 11.6 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 CDS35302.1 - 0.23 9.7 17.6 0.51 8.6 1.1 2.1 2 0 0 2 2 2 0 CDC45-like protein GAGA_bind PF06217.12 CDS35302.1 - 0.24 11.7 22.7 0.099 12.9 2.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Mpp10 PF04006.12 CDS35302.1 - 0.31 9.4 30.1 0.014 13.9 5.6 2.1 2 0 0 2 2 2 0 Mpp10 protein SR-25 PF10500.9 CDS35302.1 - 0.43 10.2 45.4 0.56 9.8 18.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 CDS35302.1 - 1.6 8.4 18.8 3.6 7.3 8.7 2.2 2 0 0 2 2 2 0 Connexin TCP PF03634.13 CDS35302.1 - 1.6 9.2 25.0 0.091 13.3 3.0 2.2 2 0 0 2 2 2 0 TCP family transcription factor RPN2_C PF18004.1 CDS35302.1 - 2.2 8.2 33.3 1.9 8.4 14.0 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 CDS35302.1 - 2.6 8.2 18.2 4 7.6 3.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CDS35302.1 - 2.7 7.8 23.5 2.2 8.0 10.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CENP-N PF05238.13 CDS35302.1 - 3.5 6.8 15.1 1.9 7.7 5.4 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like BRF1 PF07741.13 CDS35302.1 - 7.2 7.0 34.9 2.5 8.5 15.5 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Zip PF02535.22 CDS35302.1 - 8.3 5.5 9.4 0.97 8.6 0.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CobT PF06213.12 CDS35302.1 - 8.7 5.6 15.2 7.8 5.8 1.6 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT MFS_2 PF13347.6 CDS35306.1 - 0.0003 19.5 1.3 0.00079 18.1 1.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MIP PF00230.20 CDS35308.2 - 2.2e-06 27.6 0.0 2.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein gag-asp_proteas PF13975.6 CDS35312.2 - 0.0032 18.0 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDS35312.2 - 0.011 16.3 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.20 CDS35312.2 - 0.036 14.4 0.0 0.09 13.1 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1849 PF08904.11 CDS35312.2 - 0.17 11.4 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Ank_2 PF12796.7 CDS35313.2 - 1.1e-36 125.2 0.1 1.4e-11 44.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDS35313.2 - 2.1e-26 91.9 0.6 0.00012 22.5 0.0 5.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 CDS35313.2 - 2.5e-22 78.3 7.6 0.0055 17.1 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CDS35313.2 - 6.1e-21 74.2 8.3 0.00019 21.7 0.2 6.9 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDS35313.2 - 1.4e-20 71.2 9.7 0.02 15.4 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat UL41A PF17591.2 CDS35317.2 - 0.039 14.0 0.2 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL41A APG6 PF04111.12 CDS35319.1 - 0.16 11.9 0.1 0.19 11.7 0.1 1.0 1 0 0 1 1 1 0 Apg6 BARA domain DEAD PF00270.29 CDS35325.2 - 8.7e-50 168.9 0.0 1.2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDS35325.2 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDS35325.2 - 0.13 12.6 0.9 13 6.1 0.6 3.3 2 1 0 2 2 2 0 AAA domain Xylo_C PF12529.8 CDS35327.1 - 0.00045 19.9 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Fucosidase_C PF16757.5 CDS35329.1 - 1.1e-09 38.7 0.0 1.4e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain DUF1967 PF09269.11 CDS35330.1 - 0.012 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Glyco_transf_22 PF03901.17 CDS35336.1 - 3.4e-48 164.9 26.8 4.1e-48 164.6 26.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1011 PF06237.12 CDS35336.1 - 0.0022 18.3 2.4 0.0079 16.5 2.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1011) ABC_membrane PF00664.23 CDS35339.1 - 6.3e-26 91.6 5.1 7.8e-26 91.3 5.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region OpgC_C PF10129.9 CDS35339.1 - 0.0072 15.2 3.2 0.0091 14.9 3.2 1.1 1 0 0 1 1 1 1 OpgC protein PRODH PF18327.1 CDS35340.2 - 0.52 10.6 3.8 16 5.8 0.8 3.1 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain ANAPC4_WD40 PF12894.7 CDS35341.2 - 6e-07 29.7 2.2 5.5 7.4 0.1 6.2 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Aldolase_II PF00596.21 CDS35342.2 - 3.8e-30 105.2 0.2 1.2e-29 103.6 0.2 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PA26 PF04636.13 CDS35345.1 - 2.1e-09 36.9 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Serinc PF03348.15 CDS35346.1 - 2e-18 66.6 6.8 2.1e-18 66.5 6.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ADK PF00406.22 CDS35347.1 - 8e-05 22.8 0.1 0.0002 21.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase Transposase_1 PF01359.18 CDS35350.1 - 3.8e-05 23.4 0.3 7.7e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) SRI PF08236.11 CDS35350.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain EF-hand_1 PF00036.32 CDS35352.1 - 1.1e-05 24.6 0.0 0.0021 17.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CDS35352.1 - 2.1e-05 24.1 0.0 0.00036 20.2 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 CDS35352.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CDS35352.1 - 0.0016 18.9 0.0 0.0048 17.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair GPHH PF16905.5 CDS35352.1 - 0.0061 16.3 0.0 0.13 12.1 0.0 2.5 3 0 0 3 3 3 1 Voltage-dependent L-type calcium channel, IQ-associated ParD_antitoxin PF03693.14 CDS35358.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Ribosomal_L18 PF17135.4 CDS35360.1 - 1.3e-81 272.5 2.7 1.4e-81 272.3 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e HTH_41 PF14502.6 CDS35360.1 - 0.037 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L27A PF00828.19 CDS35360.1 - 0.074 13.7 0.1 0.18 12.5 0.1 1.7 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ATR13 PF16829.5 CDS35360.1 - 0.17 12.2 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Helicase_C PF00271.31 CDS35365.2 - 1.2e-08 35.3 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CDS35365.2 - 1.5e-06 27.9 8.7 1.5e-06 27.9 8.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDS35365.2 - 6.5e-05 23.2 11.8 6.5e-05 23.2 11.8 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CDS35365.2 - 6.8e-05 22.6 6.7 6.8e-05 22.6 6.7 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDS35365.2 - 7.3e-05 22.5 10.8 7.3e-05 22.5 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDS35365.2 - 0.00043 20.2 8.7 0.00043 20.2 8.7 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 CDS35365.2 - 0.0021 17.9 7.2 0.0078 16.1 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDS35365.2 - 0.0024 17.7 9.9 0.0072 16.2 9.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDS35365.2 - 0.01 15.9 7.9 0.015 15.3 5.8 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 CDS35365.2 - 0.023 14.8 3.5 0.025 14.7 1.7 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Di19 PF05605.12 CDS35365.2 - 0.041 14.2 8.6 0.82 10.0 0.1 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rtf2 PF04641.12 CDS35365.2 - 0.18 11.1 1.6 0.19 11.0 0.4 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger DZR PF12773.7 CDS35365.2 - 0.66 10.0 9.8 0.58 10.2 3.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 CDS35365.2 - 8.7 6.6 10.7 0.66 10.2 4.7 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Peptidase_M23_N PF18421.1 CDS35370.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain Peptidase_M23_N PF18421.1 CDS35371.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain EF-hand_7 PF13499.6 CDS35375.2 - 1e-21 77.1 0.3 4.7e-11 43.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CDS35375.2 - 3.6e-21 73.1 1.4 6.6e-06 25.3 0.2 5.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 CDS35375.2 - 9.4e-20 68.8 3.3 5e-05 22.9 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CDS35375.2 - 5e-17 61.5 1.1 0.00012 21.8 0.2 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CDS35375.2 - 1.3e-11 43.4 0.4 0.0079 15.6 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CDS35375.2 - 0.0024 18.2 0.0 20 5.6 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CDS35375.2 - 0.12 12.7 0.1 3.4 8.0 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mo25 PF08569.11 CDS35376.1 - 1.6e-23 83.6 0.1 1.8e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Ribosomal_S14 PF00253.21 CDS35377.1 - 1e-07 31.6 0.3 1.5e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e FAM163 PF15069.6 CDS35382.1 - 0.037 14.5 0.0 0.037 14.5 0.0 1.5 2 0 0 2 2 2 0 FAM163 family Mid2 PF04478.12 CDS35382.1 - 0.04 13.7 0.5 0.066 13.0 0.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Phage_Coat_B PF05356.11 CDS35382.1 - 3 7.8 5.9 1.1 9.2 3.3 1.6 1 1 1 2 2 2 0 Phage Coat protein B Cadherin PF00028.17 CDS35384.2 - 4.5e-55 184.1 9.4 4.3e-15 55.9 0.3 9.5 8 5 0 8 8 8 6 Cadherin domain Cadherin_2 PF08266.12 CDS35384.2 - 2.1e-13 49.9 0.0 5.6e-06 26.1 0.0 4.8 4 0 0 4 4 4 3 Cadherin-like RET_CLD1 PF17756.1 CDS35384.2 - 2.8e-07 30.9 0.0 0.48 10.7 0.0 4.4 4 0 0 4 4 4 2 RET Cadherin like domain 1 PBP PF01161.20 CDS35384.2 - 0.013 15.8 0.1 1.5 9.2 0.1 3.1 2 1 0 2 2 2 0 Phosphatidylethanolamine-binding protein PKcGMP_CC PF16808.5 CUU00195.1 - 0.14 12.1 0.1 0.14 12.1 0.1 5.0 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase JUPITER PF17054.5 CUU00195.1 - 0.16 11.4 0.6 0.79 9.1 0.3 1.9 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter DUF4407 PF14362.6 CUU00195.1 - 1.2 8.4 34.2 0.41 10.0 19.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Solute_trans_a PF03619.16 CUU00198.1 - 1.5e-79 267.3 13.0 1.8e-79 267.0 13.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Npa1 PF11707.8 CUU00199.1 - 0.00063 19.2 4.6 0.0079 15.6 0.2 3.3 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal AAA_lid_5 PF17865.1 CUU00199.1 - 0.0018 18.3 0.1 0.0074 16.3 0.1 2.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_22 PF13401.6 CUU00199.1 - 0.025 14.8 0.1 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Sec20 PF03908.13 CUU00199.1 - 0.079 12.9 0.4 0.51 10.3 0.1 2.7 2 0 0 2 2 2 0 Sec20 CAP PF00188.26 CUU00200.1 - 7.9e-22 78.4 0.0 1e-21 78.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MRP-L46 PF11788.8 CUU00201.1 - 7e-06 26.8 0.1 1.2e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.19 CUU00202.1 - 0.0057 16.3 0.0 2.1 8.2 0.0 3.3 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat SPOC PF07744.13 CUU00203.1 - 9.8e-33 113.2 0.0 2.9e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 SPOC domain RRM_1 PF00076.22 CUU00203.1 - 7.5e-08 32.1 0.0 0.095 12.5 0.0 4.1 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CUU00204.1 - 1.2e-36 126.5 0.0 1.4e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU00204.1 - 2.1e-12 46.9 0.1 6.9e-12 45.2 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CUU00204.1 - 9.5e-06 25.1 0.2 1.4e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CUU00204.1 - 0.00019 20.9 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CUU00204.1 - 0.0012 17.8 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CUU00204.1 - 0.025 14.1 1.1 0.037 13.6 1.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Toxin_trans PF07952.12 CUU00204.1 - 0.03 13.4 0.2 0.04 13.0 0.2 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Pox_ser-thr_kin PF05445.11 CUU00204.1 - 0.042 12.8 0.8 0.061 12.3 0.8 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CUU00204.1 - 0.18 11.7 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ig_3 PF13927.6 CUU00209.1 - 8.5e-54 180.1 0.1 1.5e-10 41.5 0.0 6.0 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.16 CUU00209.1 - 1.5e-43 146.7 0.0 3.1e-12 46.4 0.0 5.9 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.6 CUU00209.1 - 4.6e-26 91.0 0.2 1.3e-05 25.5 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 CUU00209.1 - 6.3e-26 90.4 0.1 2.6e-06 27.5 0.0 6.4 6 1 0 6 6 5 4 Immunoglobulin domain V-set PF07686.17 CUU00209.1 - 1.2e-18 67.2 2.9 0.01 16.0 0.1 7.9 6 3 1 7 7 7 4 Immunoglobulin V-set domain fn3 PF00041.21 CUU00209.1 - 3.8e-18 65.6 3.2 9.7e-08 32.3 0.0 4.2 4 0 0 4 4 4 2 Fibronectin type III domain Ig_6 PF18452.1 CUU00209.1 - 4.8e-13 48.4 0.0 0.038 13.6 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain Ig_5 PF16681.5 CUU00209.1 - 0.0016 18.8 0.2 0.32 11.4 0.0 4.3 6 0 0 6 6 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CUU00209.1 - 0.011 15.7 0.0 41 4.3 0.0 4.3 4 0 0 4 4 4 0 Izumo-like Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CUU00209.1 - 0.02 15.5 0.2 0.95 10.1 0.1 3.5 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 CUU00209.1 - 0.048 13.9 0.1 0.2 11.9 0.1 2.0 1 0 0 1 1 1 0 SusE outer membrane protein Herpes_gE PF02480.16 CUU00209.1 - 0.069 11.9 0.2 4.6 5.9 0.0 3.1 2 1 2 4 4 4 0 Alphaherpesvirus glycoprotein E fn3_4 PF16794.5 CUU00209.1 - 0.087 12.8 0.1 2.4 8.1 0.1 3.0 2 1 0 2 2 2 0 Fibronectin-III type domain Tissue_fac PF01108.17 CUU00209.1 - 0.22 11.4 2.1 0.36 10.7 0.9 2.0 2 0 0 2 2 2 0 Tissue factor G10 PF01125.17 CUU00215.1 - 5e-65 217.7 6.2 5.5e-65 217.6 6.2 1.0 1 0 0 1 1 1 1 G10 protein Alk_phosphatase PF00245.20 CUU00216.1 - 1.6e-38 132.8 0.1 2e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase JAKMIP_CC3 PF16034.5 CUU00217.1 - 9.5e-06 25.7 14.3 9.5e-06 25.7 14.3 5.5 2 1 2 5 5 5 1 JAKMIP CC3 domain EIAV_Rev PF11129.8 CUU00217.1 - 6.9 6.9 7.5 0.87 9.8 0.6 3.0 3 1 1 4 4 4 0 Rev protein of equine infectious anaemia virus AC_N PF16214.5 CUU00223.1 - 0.055 12.6 0.9 0.089 11.9 0.9 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF702 PF05142.12 CUU00223.1 - 0.7 10.4 5.5 0.2 12.1 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Adeno_E3_15_3 PF03307.14 CUU00224.1 - 0.16 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region CX9C PF16860.5 CUU00225.1 - 2e-05 24.5 10.1 0.00059 19.8 0.6 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CUU00225.1 - 5.5e-05 23.2 10.3 0.038 14.1 3.1 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 CUU00225.1 - 0.011 15.8 0.3 0.011 15.8 0.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CUU00225.1 - 1.6 9.0 10.1 3.9 7.8 6.0 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Ank_2 PF12796.7 CUU00226.1 - 1.4e-25 89.7 0.8 3.2e-15 56.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU00226.1 - 9.7e-18 64.3 0.2 1.3e-12 48.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU00226.1 - 2e-16 58.4 0.2 9.9e-05 22.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CUU00226.1 - 8e-14 51.4 0.5 0.0018 18.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CUU00226.1 - 1.6e-09 37.8 0.5 0.0044 17.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) BRCT PF00533.26 CUU00226.1 - 6.4e-05 23.3 0.0 0.035 14.5 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CUU00226.1 - 0.00019 21.7 0.0 0.22 12.0 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-RING_6 PF14835.6 CUU00226.1 - 0.013 15.4 9.1 0.12 12.3 9.1 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein GrpE PF01025.19 CUU00226.1 - 0.056 13.1 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 GrpE RTT107_BRCT_5 PF16770.5 CUU00226.1 - 0.11 12.3 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_5 PF14634.6 CUU00226.1 - 0.68 9.9 17.2 0.14 12.1 12.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.21 CUU00226.1 - 1.2 9.3 8.4 39 4.5 6.9 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_2 PF13639.6 CUU00226.1 - 3.7 8.0 11.8 11 6.4 11.8 1.9 1 0 0 1 1 1 0 Ring finger domain GLE1 PF07817.13 CUU00227.1 - 1.4e-27 96.5 0.0 4.9e-27 94.7 0.0 1.8 1 1 0 1 1 1 1 GLE1-like protein TAF6_C PF07571.13 CUU00227.1 - 0.11 12.8 0.0 1.2 9.5 0.0 2.5 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain SH3_2 PF07653.17 CUU00228.1 - 0.00022 20.9 0.4 0.0088 15.7 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.6 CUU00228.1 - 0.0084 15.9 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CUU00228.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Fip1 PF05182.13 CUU00229.1 - 4.1e-20 71.0 1.5 8.6e-20 70.0 1.5 1.5 1 0 0 1 1 1 1 Fip1 motif Pribosyltran PF00156.27 CUU00234.1 - 1.7e-21 76.4 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CUU00234.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HSA PF07529.13 CUU00235.1 - 1.5e-13 50.8 1.0 5.5e-13 49.0 0.3 2.2 1 1 1 2 2 2 1 HSA HSA PF07529.13 CUU00236.1 - 1.1e-12 48.1 0.6 2.9e-12 46.7 0.4 1.9 1 1 1 2 2 2 1 HSA SNF2_N PF00176.23 CUU00236.1 - 5e-07 28.8 0.0 8.2e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ASC PF00858.24 CUU00238.1 - 4.1e-25 88.7 0.1 2.7e-24 85.9 0.0 1.8 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel Tyr_Deacylase PF02580.16 CUU00239.1 - 2.2e-05 25.0 0.0 3.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Transglut_core PF01841.19 CUU00240.1 - 2.9e-13 50.2 0.0 1.9e-05 25.1 0.0 4.5 4 0 0 4 4 4 3 Transglutaminase-like superfamily OpgC_C PF10129.9 CUU00240.1 - 1.4e-06 27.5 8.8 0.2 10.5 0.3 3.2 3 0 0 3 3 3 3 OpgC protein Pro_isomerase PF00160.21 CUU00241.1 - 1.1e-49 168.7 0.0 2.6e-49 167.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CUU00241.1 - 0.00077 18.9 1.5 0.045 13.1 0.0 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger Fcf2 PF08698.11 CUU00241.1 - 0.072 13.5 0.7 0.2 12.1 0.4 2.0 2 1 0 2 2 2 0 Fcf2 pre-rRNA processing DUF2027 PF09640.10 CUU00242.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) TruD PF01142.18 CUU00243.1 - 4.5e-72 243.1 0.0 3.7e-57 194.0 0.0 3.8 2 1 2 4 4 4 2 tRNA pseudouridine synthase D (TruD) DUF722 PF05263.11 CUU00244.1 - 0.0056 16.9 0.0 0.0064 16.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF722) DUF4604 PF15377.6 CUU00246.1 - 0.66 10.4 13.4 0.041 14.3 6.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Beach PF02138.18 CUU00248.1 - 1.4e-22 80.4 0.1 1.5e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Exo_endo_phos_2 PF14529.6 CUU00249.1 - 1.6e-13 50.5 0.3 3.2e-13 49.6 0.3 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CUU00249.1 - 7.1e-05 22.4 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CUU00251.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CUU00251.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CUU00251.1 - 0.12 13.1 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease HTH_20 PF12840.7 CUU00252.1 - 0.045 13.8 0.4 0.79 9.8 0.1 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain RVT_1 PF00078.27 CUU00253.1 - 4e-30 105.0 0.1 7.1e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CUU00253.1 - 0.047 14.2 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_20 PF12840.7 CUU00254.1 - 0.064 13.3 0.1 0.79 9.8 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain zf_ZIC PF18366.1 CUU00255.1 - 3e-08 33.6 0.8 3e-08 33.6 0.8 3.1 3 1 0 3 3 3 1 Zic proteins zinc finger domain zf-H2C2_2 PF13465.6 CUU00255.1 - 4.3e-07 30.1 1.4 4.3e-07 30.1 1.4 4.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 CUU00255.1 - 0.00049 20.4 23.7 0.0019 18.6 1.6 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU00255.1 - 0.0048 17.6 2.8 0.08 13.8 1.6 4.5 5 0 0 5 5 5 2 C2H2-type zinc finger Glycoprotein PF03409.15 CUU00255.1 - 0.0051 15.7 2.5 0.007 15.3 2.5 1.1 1 0 0 1 1 1 1 Transmembrane glycoprotein FOXP-CC PF16159.5 CUU00255.1 - 0.038 14.6 7.5 3.3 8.4 0.3 3.6 1 1 2 3 3 3 0 FOXP coiled-coil domain SVWC PF15430.6 CUU00255.1 - 0.046 14.0 1.5 0.84 10.0 0.5 2.5 2 0 0 2 2 2 0 Single domain von Willebrand factor type C DUF2158 PF09926.9 CUU00255.1 - 0.19 11.5 1.7 3.6 7.4 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2158) zf-CXXC PF02008.20 CUU00257.1 - 3.8e-09 36.4 44.2 1e-05 25.4 16.6 2.9 3 0 0 3 3 3 2 CXXC zinc finger domain RVT_1 PF00078.27 CUU00259.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PAPS_reduct PF01507.19 CUU00259.1 - 0.039 14.0 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Pribosyl_synth PF14572.6 CUU00260.1 - 1.8e-79 266.0 0.1 4e-60 203.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CUU00260.1 - 1.8e-38 131.1 0.1 8e-38 128.9 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CUU00260.1 - 9.7e-08 31.7 0.1 2.4e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Ig_3 PF13927.6 CUU00261.1 - 3e-16 59.8 0.0 3.1e-07 30.9 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CUU00261.1 - 2.3e-15 56.4 0.0 7.6e-06 25.9 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain ig PF00047.25 CUU00261.1 - 1.6e-11 44.2 0.1 1.1e-05 25.5 0.0 4.3 4 0 0 4 4 4 2 Immunoglobulin domain Ig_2 PF13895.6 CUU00261.1 - 3e-11 43.5 0.0 1.2e-05 25.5 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.17 CUU00261.1 - 7.6e-06 26.1 0.5 1.4 9.1 0.1 4.2 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CUU00261.1 - 0.0036 16.8 0.0 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain BORCS6 PF10157.9 CUU00264.1 - 1.6e-25 90.1 2.7 1.9e-25 89.9 2.7 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 DegS PF05384.11 CUU00264.1 - 0.0068 15.9 0.8 0.035 13.6 0.2 1.9 2 0 0 2 2 2 1 Sensor protein DegS Katanin_con80 PF13925.6 CUU00264.1 - 0.088 12.8 2.2 0.11 12.6 2.2 1.1 1 0 0 1 1 1 0 con80 domain of Katanin COG5 PF10392.9 CUU00264.1 - 0.13 12.4 4.0 0.49 10.6 0.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Thioredoxin PF00085.20 CUU00265.1 - 9.6e-12 44.8 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Ig_3 PF13927.6 CUU00266.1 - 6.7e-15 55.4 0.9 3.7e-07 30.6 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CUU00266.1 - 8.8e-13 48.1 0.0 0.00014 21.9 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain ig PF00047.25 CUU00266.1 - 3.6e-10 39.9 0.5 0.0055 16.8 0.1 3.6 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CUU00266.1 - 1.1e-09 38.5 0.2 0.0062 16.8 0.0 3.8 2 2 1 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CUU00266.1 - 1.1e-07 32.0 0.1 0.00088 19.4 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_4 PF16680.5 CUU00266.1 - 0.037 14.3 0.0 4.4 7.7 0.0 3.4 3 1 1 4 4 4 0 T-cell surface glycoprotein CD3 delta chain C2-set_2 PF08205.12 CUU00266.1 - 0.047 13.8 0.0 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CUU00266.1 - 0.14 11.8 0.0 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin domain zf-C3HC4_3 PF13920.6 CUU00267.1 - 4.1e-05 23.4 8.4 4.1e-05 23.4 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 CUU00267.1 - 0.0001 22.9 3.3 0.0001 22.9 3.3 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_4 PF14570.6 CUU00267.1 - 0.014 15.2 6.8 0.014 15.2 6.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Sina PF03145.16 CUU00267.1 - 0.02 14.9 3.1 0.02 14.9 3.1 1.7 2 0 0 2 2 2 0 Seven in absentia protein family Prok-RING_4 PF14447.6 CUU00267.1 - 0.36 10.7 8.8 1.3 8.9 8.8 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CUU00267.1 - 7 6.8 10.3 26 4.9 10.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger TPR_MLP1_2 PF07926.12 CUU00268.1 - 0.2 11.7 8.7 0.34 11.0 8.7 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Hydrolase_6 PF13344.6 CUU00270.1 - 7.2e-15 54.9 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CUU00270.1 - 9.7e-10 38.4 0.0 3.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 HAD-hyrolase-like Cyt-b5 PF00173.28 CUU00271.1 - 9.3e-09 35.3 0.0 2.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RhoGEF PF00621.20 CUU00273.1 - 2.8e-08 34.2 0.1 8.5e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain UDPGP PF01704.18 CUU00275.1 - 1.5e-39 135.8 0.0 4e-39 134.4 0.0 1.6 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CUU00275.1 - 0.00098 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_47 PF01532.20 CUU00276.1 - 6.4e-113 378.1 0.0 8.6e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cactin_mid PF10312.9 CUU00277.1 - 5.5e-45 153.5 1.3 5.5e-45 153.5 1.3 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin Tim17 PF02466.19 CUU00277.1 - 8.9e-23 80.8 6.9 1.5e-22 80.1 6.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AAA_33 PF13671.6 CUU00277.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.7 3 1 1 4 4 4 0 AAA domain Romo1 PF10247.9 CUU00277.1 - 3.6 8.0 7.7 2.1 8.8 0.2 2.5 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DDRGK PF09756.9 CUU00277.1 - 9.2 5.8 24.4 0.77 9.3 9.9 2.7 2 0 0 2 2 2 0 DDRGK domain 5-FTHF_cyc-lig PF01812.20 CUU00278.1 - 1.4e-27 96.8 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Tyr_Deacylase PF02580.16 CUU00279.1 - 1.6e-06 28.7 0.0 1.8e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Cnd1_N PF12922.7 CUU00280.1 - 1.1e-21 77.4 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Med8 PF10232.9 CUU00281.1 - 1.3e-29 103.4 2.8 1.6e-29 103.2 2.8 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Annexin PF00191.20 CUU00282.1 - 2.3e-28 98.0 0.8 1.4e-17 63.5 0.1 2.1 2 0 0 2 2 2 2 Annexin Ribosomal_L37ae PF01780.19 CUU00282.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family Homeobox_KN PF05920.11 CUU00284.1 - 8.8e-16 57.5 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CUU00284.1 - 1.8e-07 30.9 0.9 2.8e-07 30.3 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CUU00284.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Phage_P2_GpE PF06528.12 CUU00284.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE Nuc_sug_transp PF04142.15 CUU00288.1 - 6e-60 203.1 19.1 8.9e-39 133.5 10.6 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter DMT_6 PF04342.12 CUU00288.1 - 0.0091 16.2 8.5 0.0096 16.1 2.6 2.3 2 0 0 2 2 2 1 Putative member of DMT superfamily (DUF486) EamA PF00892.20 CUU00288.1 - 0.039 14.1 18.8 0.42 10.8 0.7 2.4 2 1 0 2 2 2 0 EamA-like transporter family CRT-like PF08627.10 CUU00288.1 - 0.079 11.9 10.7 0.017 14.0 3.1 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Glyco_hydro_2 PF00703.21 CUU00289.1 - 0.012 16.3 0.0 0.02 15.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 CUU00290.1 - 1.4e-10 40.7 0.1 2.4e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 CUU00290.1 - 0.045 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain E1-E2_ATPase PF00122.20 CUU00291.1 - 2.9e-34 118.2 7.4 5.8e-23 81.3 0.1 2.6 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 CUU00291.1 - 4.7e-18 65.1 0.0 9.1e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CUU00291.1 - 1e-15 57.2 0.0 3.4e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2976 PF11190.8 CUU00291.1 - 3.3e-05 23.6 4.3 0.0059 16.4 0.3 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) Yip1 PF04893.17 CUU00291.1 - 0.022 14.5 1.4 0.9 9.2 0.1 2.3 2 0 0 2 2 2 0 Yip1 domain Transgly_assoc PF04226.13 CUU00291.1 - 0.087 13.1 0.3 0.087 13.1 0.3 2.9 3 0 0 3 3 3 0 Transglycosylase associated protein Hydrolase PF00702.26 CUU00291.1 - 0.14 12.4 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DctQ PF04290.12 CUU00291.1 - 1.9 8.4 5.3 13 5.7 0.6 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component FtsX PF02687.21 CUU00291.1 - 4.6 7.8 8.5 2.6 8.6 0.2 2.5 2 0 0 2 2 2 0 FtsX-like permease family PDZ PF00595.24 CUU00292.1 - 1.9e-11 44.1 0.1 3.3e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CUU00292.1 - 1.1e-06 28.3 0.1 2.3e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain NRho PF16733.5 CUU00292.1 - 0.0043 17.1 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Rhomboid N-terminal domain CDK5_activator PF03261.15 CUU00293.1 - 6.8e-54 183.8 5.4 3e-45 155.3 0.8 2.5 2 0 0 2 2 2 2 Cyclin-dependent kinase 5 activator protein zf-RING_2 PF13639.6 CUU00294.1 - 0.00012 22.4 7.6 0.00012 22.4 7.6 3.8 4 1 1 5 5 5 1 Ring finger domain Zn_ribbon_17 PF17120.5 CUU00294.1 - 0.0012 18.4 4.8 0.0012 18.4 4.8 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CUU00294.1 - 0.0029 17.4 1.2 0.0029 17.4 1.2 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CUU00294.1 - 0.0061 16.8 7.1 0.0061 16.8 7.1 3.3 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 CUU00294.1 - 0.0082 16.4 6.2 0.084 13.1 6.2 2.3 1 1 0 1 1 1 1 PHD-like zinc-binding domain Ogr_Delta PF04606.12 CUU00294.1 - 0.022 14.7 0.6 0.078 13.0 0.6 1.9 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C3HC4 PF00097.25 CUU00294.1 - 0.026 14.4 7.4 0.026 14.4 7.4 2.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CUU00294.1 - 0.053 13.3 1.7 0.053 13.3 1.7 3.2 4 1 0 4 4 4 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CUU00294.1 - 0.068 13.2 8.0 0.24 11.5 5.6 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CUU00294.1 - 0.073 13.2 6.1 1.5 9.0 4.9 3.0 2 1 0 2 2 2 0 RING-variant domain QVR PF17064.5 CUU00295.1 - 5.9e-25 87.3 4.5 5.9e-25 87.3 4.5 2.3 2 1 0 2 2 2 1 Sleepless protein zf-RING_2 PF13639.6 CUU00295.1 - 1e-12 48.2 5.9 1e-12 48.2 5.9 3.1 4 0 0 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 CUU00295.1 - 7.4e-10 38.4 2.7 7.4e-10 38.4 2.7 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CUU00295.1 - 4.1e-08 32.9 5.7 4.1e-08 32.9 5.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CUU00295.1 - 1.5e-07 31.1 6.2 1.5e-07 31.1 6.2 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CUU00295.1 - 2.9e-06 27.5 8.8 2.9e-06 27.5 8.8 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CUU00295.1 - 4.8e-06 26.4 3.8 4.8e-06 26.4 3.8 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CUU00295.1 - 1.7e-05 24.7 1.8 4.2e-05 23.5 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CUU00295.1 - 0.0001 22.2 1.3 0.0001 22.2 1.3 3.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CUU00295.1 - 0.00012 21.9 4.0 0.00012 21.9 4.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CUU00295.1 - 0.0056 16.5 7.4 0.0056 16.5 7.4 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CUU00295.1 - 0.019 14.8 1.0 0.019 14.8 1.0 2.2 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit DUF753 PF05444.12 CUU00295.1 - 0.069 13.1 0.2 0.069 13.1 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF753) Zn_ribbon_17 PF17120.5 CUU00295.1 - 0.96 9.1 7.6 0.15 11.7 2.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CUU00295.1 - 1.5 9.1 13.0 0.32 11.2 6.1 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain Homeodomain PF00046.29 CUU00297.1 - 1.5e-20 72.8 7.7 3e-20 71.8 7.7 1.5 1 0 0 1 1 1 1 Homeodomain TyeA PF09059.10 CUU00297.1 - 0.12 12.5 0.4 0.23 11.6 0.4 1.5 1 1 0 1 1 1 0 TyeA LOH1CR12 PF10158.9 CUU00302.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein PRK PF00485.18 CUU00305.1 - 2.9e-16 59.8 0.1 3.8e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family PRK PF00485.18 CUU00306.1 - 5.1e-05 23.1 2.1 0.00019 21.2 0.0 1.9 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family HLH PF00010.26 CUU00307.1 - 9.2e-12 44.7 0.8 1.8e-11 43.8 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 CUU00307.1 - 3.9e-06 26.8 0.0 0.00037 20.5 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 CUU00307.1 - 0.0002 21.6 0.0 0.0064 16.7 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 CUU00307.1 - 0.0009 19.4 0.0 0.0051 16.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 CUU00307.1 - 0.017 15.3 0.0 5.7 7.3 0.0 2.5 2 0 0 2 2 2 0 PAS domain RRM_1 PF00076.22 CUU00308.1 - 3.8e-05 23.4 0.3 0.00019 21.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 CUU00314.1 - 4.4e-19 68.2 0.9 4.2e-09 36.2 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein SOSSC PF15925.5 CUU00317.1 - 0.034 15.5 0.5 0.034 15.5 0.5 2.9 2 1 1 3 3 3 0 SOSS complex subunit C BTB_2 PF02214.22 CUU00318.1 - 3.3e-14 53.0 0.0 6.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CUU00318.1 - 0.00068 18.9 0.8 0.0011 18.2 0.8 1.4 1 0 0 1 1 1 1 Ion transport protein Ependymin PF00811.18 CUU00318.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Ependymin BTB_3 PF16017.5 CUU00318.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Ion_trans PF00520.31 CUU00319.1 - 1.2e-19 70.5 8.7 1.6e-19 70.1 8.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CUU00319.1 - 2.4e-10 40.2 7.8 3.8e-10 39.6 7.8 1.3 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 CUU00319.1 - 0.0069 15.1 1.6 0.01 14.6 1.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Phage_holin_2_4 PF16082.5 CUU00319.1 - 0.28 10.9 1.2 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like IRK PF01007.20 CUU00319.1 - 0.69 9.7 4.1 3.3 7.5 4.1 1.9 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain PI-PLC-X PF00388.19 CUU00320.1 - 7e-61 204.1 0.0 1.3e-60 203.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CUU00320.1 - 2.3e-44 150.4 4.6 1.3e-37 128.7 0.5 2.9 2 1 0 3 3 3 2 Phosphatidylinositol-specific phospholipase C, Y domain PH_14 PF17787.1 CUU00320.1 - 2.5e-37 127.6 0.0 6.4e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 CUU00320.1 - 5.3e-08 33.2 0.1 1.9e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1154 PF06631.11 CUU00321.1 - 1e-18 67.0 1.0 1e-18 67.0 1.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) Memo PF01875.17 CUU00324.1 - 0.00067 18.9 0.0 0.001 18.3 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein Yqai PF09466.10 CUU00329.1 - 0.0052 17.1 0.0 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein Yqai RNA_pol_Rpb1_1 PF04997.12 CUU00330.1 - 2.5e-104 349.0 0.4 4.7e-104 348.1 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CUU00330.1 - 2.2e-102 342.1 0.1 3.2e-102 341.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CUU00330.1 - 1.7e-70 236.5 0.1 3.1e-70 235.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CUU00330.1 - 1.9e-62 210.5 1.9 3.5e-62 209.6 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CUU00330.1 - 2e-47 161.0 0.0 4.8e-47 159.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 CUU00330.1 - 6.2e-42 142.8 1.8 1.6e-41 141.4 1.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 CUU00330.1 - 1.9e-37 127.5 0.2 6.5e-37 125.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 tRNA_m1G_MT PF01746.21 CUU00331.1 - 1.9e-20 73.4 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase COX7C PF02935.16 CUU00332.1 - 0.014 15.7 2.1 0.14 12.4 0.3 3.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc SDF PF00375.18 CUU00333.1 - 6.5e-09 35.3 0.5 9e-09 34.8 0.5 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TRAM_LAG1_CLN8 PF03798.16 CUU00338.1 - 0.27 10.9 6.6 0.38 10.5 6.2 1.4 1 1 0 1 1 1 0 TLC domain EF-hand_1 PF00036.32 CUU00341.1 - 7.3e-15 53.3 1.2 2.9e-07 29.5 0.9 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CUU00341.1 - 2.3e-13 48.9 0.7 1.5e-05 24.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CUU00341.1 - 2e-11 42.8 2.3 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CUU00341.1 - 1.5e-09 38.2 0.9 3.6e-09 37.0 0.9 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CUU00341.1 - 1.9e-06 27.6 0.3 0.046 13.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CUU00341.1 - 0.00023 21.1 0.2 0.00025 20.9 0.2 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CUU00341.1 - 0.0035 17.6 0.2 2.7 8.3 0.0 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CUU00341.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain NTS_2 PF15448.6 CUU00342.1 - 0.0037 17.6 3.0 2.8 8.4 0.2 2.9 3 0 0 3 3 3 2 N-terminal segments of P. falciparum erythrocyte membrane protein DUF739 PF05339.11 CUU00342.1 - 0.013 15.6 0.1 6.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF739) MLD PF11647.8 CUU00342.1 - 0.05 13.9 0.9 11 6.3 0.1 2.5 1 1 0 2 2 2 0 Membrane Localization Domain Antimicrobial_9 PF08104.11 CUU00342.1 - 0.07 13.1 3.2 1.4 9.0 0.9 2.4 2 0 0 2 2 2 0 Ponericin L family zf-UBR PF02207.20 CUU00343.1 - 4.5e-19 68.4 12.9 4.5e-19 68.4 12.9 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CUU00343.1 - 1.2e-14 53.8 0.1 3.8e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-B_box PF00643.24 CUU00343.1 - 3.7 7.8 14.2 0.1 12.7 7.0 2.2 2 0 0 2 2 2 0 B-box zinc finger Chromo_shadow PF01393.19 CUU00347.1 - 8.1e-31 105.9 0.1 4.9e-28 97.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CUU00347.1 - 1.6e-22 79.2 1.3 2.3e-18 65.8 1.5 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SBD_N PF07005.11 CUU00347.1 - 0.098 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Sugar-binding N-terminal domain MARVEL PF01284.23 CUU00348.1 - 1.6e-07 31.5 1.9 2e-07 31.1 1.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain rve PF00665.26 CUU00350.1 - 6.5e-08 32.8 0.0 9.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CUU00350.1 - 0.00082 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DHHC PF01529.20 CUU00351.1 - 1.1e-05 25.5 4.1 1.7e-05 24.9 4.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase TP6A_N PF04406.14 CUU00353.1 - 9.4e-08 31.9 0.2 1.6e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase gag-asp_proteas PF13975.6 CUU00354.1 - 0.098 13.2 0.0 0.33 11.5 0.0 1.9 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease EF-hand_7 PF13499.6 CUU00355.1 - 2.5e-21 75.9 8.4 2.3e-12 47.2 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CUU00355.1 - 5.1e-21 72.6 11.7 2.9e-06 26.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CUU00355.1 - 7.5e-18 62.9 8.5 3.2e-06 26.6 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CUU00355.1 - 3.1e-11 42.9 12.0 2.8e-07 30.3 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU00355.1 - 9.4e-10 37.5 13.1 0.00026 20.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 CUU00355.1 - 7.6e-07 29.0 2.1 0.0081 16.1 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CUU00355.1 - 6.9e-05 23.1 1.6 0.028 14.7 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CUU00355.1 - 0.00084 19.6 5.4 0.28 11.5 1.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CUU00355.1 - 0.0066 16.4 0.2 13 5.7 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein Death PF00531.22 CUU00355.1 - 0.13 12.5 0.1 3.4 7.9 0.1 2.4 1 1 0 1 1 1 0 Death domain KH_1 PF00013.29 CUU00356.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CUU00356.1 - 0.0023 17.7 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 KH domain CH PF00307.31 CUU00359.1 - 2.2e-12 47.1 0.0 3.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CUU00359.1 - 5.6e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Pkinase PF00069.25 CUU00360.1 - 1.2e-20 74.0 0.0 2.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU00360.1 - 4.5e-06 26.1 0.0 7.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-S23 PF10484.9 CUU00360.1 - 0.072 13.4 1.4 0.23 11.7 0.7 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 UDPGP PF01704.18 CUU00363.1 - 1.3e-184 613.7 0.0 1.5e-184 613.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Glycos_transf_2 PF00535.26 CUU00364.1 - 1e-13 51.5 0.0 1.2e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CUU00364.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CUU00364.1 - 0.056 13.3 0.0 0.089 12.7 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase like family 2 DUF4545 PF15078.6 CUU00366.1 - 0.19 10.7 5.9 0.13 11.2 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4545) SPX PF03105.19 CUU00366.1 - 0.24 11.3 7.7 0.28 11.0 7.7 1.1 1 0 0 1 1 1 0 SPX domain DUF4769 PF15992.5 CUU00366.1 - 0.3 10.8 11.5 0.072 12.9 7.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4769) AIP3 PF03915.13 CUU00367.1 - 1.9e-12 47.0 2.9 2.5e-12 46.6 2.9 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 HR1 PF02185.16 CUU00367.1 - 0.023 14.8 1.2 0.023 14.8 1.2 2.9 3 0 0 3 3 3 0 Hr1 repeat Phage_GP20 PF06810.11 CUU00367.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Prefoldin_3 PF13758.6 CUU00367.1 - 2 8.5 5.7 1.3 9.1 1.0 2.5 3 0 0 3 3 3 0 Prefoldin subunit PQ-loop PF04193.14 CUU00370.1 - 4.2e-08 32.8 0.4 4.2e-08 32.8 0.4 2.7 1 1 2 3 3 3 1 PQ loop repeat DUF2955 PF11168.8 CUU00370.1 - 0.032 14.1 2.5 0.041 13.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) HMG_box PF00505.19 CUU00371.1 - 9.3e-26 90.1 2.9 2.5e-25 88.6 2.9 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CUU00371.1 - 1.2e-09 38.7 1.3 3.3e-09 37.2 1.3 1.8 1 0 0 1 1 1 1 HMG-box domain Integrin_b_cyt PF08725.11 CUU00376.1 - 0.069 12.8 1.1 0.15 11.8 1.1 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RRM_1 PF00076.22 CUU00377.1 - 1.3e-16 60.2 4.3 1.2e-09 37.8 0.7 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CUU00377.1 - 8.9e-05 22.5 0.2 0.024 14.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CUU00377.1 - 0.019 15.0 0.1 0.62 10.1 0.0 2.7 2 2 0 2 2 2 0 RNA binding motif P30 PF07390.11 CUU00377.1 - 0.082 13.0 5.5 0.39 10.8 0.1 2.7 2 1 0 2 2 2 0 Mycoplasma P30 protein Nup35_RRM_2 PF14605.6 CUU00377.1 - 0.22 11.6 2.2 0.64 10.1 0.1 2.7 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif cwf21 PF08312.12 CUU00379.1 - 5.6e-15 55.2 3.4 5.6e-15 55.2 3.4 3.0 3 1 0 3 3 3 1 cwf21 domain DUF4228 PF14009.6 CUU00379.1 - 0.23 11.8 14.8 1.3 9.4 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 CUU00379.1 - 1.2 7.3 22.9 1.6 6.9 22.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5352 PF17303.2 CUU00379.1 - 4.5 7.1 9.1 0.67 9.8 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5352) cwf21 PF08312.12 CUU00380.1 - 5.6e-15 55.2 3.4 5.6e-15 55.2 3.4 3.0 3 1 0 3 3 3 1 cwf21 domain DUF4228 PF14009.6 CUU00380.1 - 0.23 11.8 14.8 1.3 9.4 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 CUU00380.1 - 1.2 7.3 22.9 1.6 6.9 22.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5352 PF17303.2 CUU00380.1 - 4.5 7.1 9.1 0.67 9.8 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5352) cwf21 PF08312.12 CUU00381.1 - 4.8e-15 55.4 3.4 4.8e-15 55.4 3.4 3.1 3 1 0 3 3 3 1 cwf21 domain DUF4228 PF14009.6 CUU00381.1 - 0.25 11.7 15.2 1.1 9.7 12.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 CUU00381.1 - 0.97 7.6 22.9 1.3 7.2 22.9 1.2 1 0 0 1 1 1 0 CDC45-like protein C2 PF00168.30 CUU00382.1 - 0.0089 16.3 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain 7tm_1 PF00001.21 CUU00383.1 - 2.1e-07 30.6 3.7 6.8e-07 28.9 3.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RasGEF PF00617.19 CUU00384.1 - 2.7e-08 34.2 0.2 0.015 15.5 0.0 3.0 3 1 0 3 3 3 2 RasGEF domain RasGEF PF00617.19 CUU00385.1 - 1.8e-25 90.2 0.7 4.8e-24 85.5 0.7 2.5 1 1 0 1 1 1 1 RasGEF domain DUF5393 PF17371.2 CUU00385.1 - 0.00036 18.8 0.9 0.0005 18.3 0.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5393) PRF PF06875.11 CUU00385.1 - 0.018 14.5 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF RUN PF02759.19 CUU00385.1 - 0.022 14.7 2.2 9.5 6.2 0.0 3.5 3 1 0 3 3 3 0 RUN domain PRA-PH PF01503.17 CUU00385.1 - 0.063 13.7 0.0 0.18 12.2 0.0 2.0 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF1644 PF07800.12 CUU00386.1 - 0.0073 16.4 1.1 0.0082 16.2 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) ChaC PF04752.12 CUU00389.1 - 3e-50 170.8 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Creatinase_N_2 PF16189.5 CUU00391.1 - 1e-40 139.4 0.0 1.1e-39 136.1 0.0 2.5 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CUU00391.1 - 3e-34 118.5 0.0 4.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CUU00391.1 - 4.3e-20 72.7 0.0 1.1e-16 61.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CUU00391.1 - 5.5e-19 68.0 0.0 1.5e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Nrap_D4 PF17405.2 CUU00392.1 - 1.2e-20 73.8 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 CUU00392.1 - 1.2e-18 67.5 0.0 6.6e-15 55.2 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CUU00392.1 - 1.4e-16 61.0 0.0 3.2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 AhpC-TSA_2 PF13911.6 CUU00395.1 - 1.8e-20 73.2 0.1 2.4e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CUU00395.1 - 2.7e-05 24.1 0.0 3.5e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CUU00395.1 - 6.3e-05 22.7 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Redoxin NAD_binding_1 PF00175.21 CUU00396.1 - 6.9e-28 97.5 0.0 8.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CUU00396.1 - 4e-07 30.3 0.1 3e-06 27.4 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CUU00396.1 - 0.0097 16.2 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_6 PF00970.24 CUU00398.1 - 2.9e-26 91.7 0.0 4.1e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CUU00399.1 - 4e-27 95.0 0.0 6.7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CUU00399.1 - 7.7e-26 90.3 0.0 2e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain LSM PF01423.22 CUU00399.1 - 1.9e-18 65.9 2.7 3.3e-18 65.1 2.7 1.4 1 0 0 1 1 1 1 LSM domain NAD_binding_6 PF08030.12 CUU00399.1 - 3.1e-06 27.4 0.1 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxysterol_BP PF01237.18 CUU00401.1 - 2e-128 428.4 0.0 3.4e-128 427.6 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CUU00402.1 - 0.0011 19.4 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 PH domain ArdA PF07275.11 CUU00402.1 - 0.016 15.8 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Golgin_A5 PF09787.9 CUU00402.1 - 0.074 12.5 1.6 0.1 12.0 0.1 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 MbeD_MobD PF04899.12 CUU00402.1 - 2.4 8.3 6.5 0.82 9.8 2.3 2.2 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_C13 PF01650.18 CUU00403.1 - 2.1e-26 93.0 0.1 2.8e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family BRE1 PF08647.11 CUU00406.1 - 0.0035 17.4 4.9 0.0035 17.4 4.9 6.4 6 2 1 7 7 7 1 BRE1 E3 ubiquitin ligase L31 PF09784.9 CUU00406.1 - 0.44 11.0 7.3 0.34 11.3 2.5 3.2 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 RAI16-like PF10257.9 CUU00410.1 - 1.3e-37 129.5 13.1 4.3e-36 124.6 13.1 2.1 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein tRNA-synt_1c PF00749.21 CUU00411.1 - 4e-168 558.1 0.0 1.5e-54 185.1 0.0 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (E and Q), catalytic domain NAPRTase_N PF17767.1 CUU00411.1 - 0.00089 19.6 0.1 4.5 7.7 0.0 3.5 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF1010 PF06231.11 CUU00411.1 - 0.00097 19.6 0.0 35 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1010) Fusion_gly PF00523.18 CUU00411.1 - 0.001 17.4 0.2 10 4.2 0.0 3.6 4 0 0 4 4 4 3 Fusion glycoprotein F0 Toprim_C_rpt PF13368.6 CUU00411.1 - 0.016 15.2 6.9 14 5.8 0.2 3.4 3 0 0 3 3 3 0 Topoisomerase C-terminal repeat Ntox28 PF15605.6 CUU00411.1 - 0.019 15.2 0.1 86 3.5 0.0 3.6 3 0 0 3 3 3 0 Bacterial toxin 28 GST_C_4 PF14834.6 CUU00411.1 - 0.055 13.9 0.1 1.2e+02 3.1 0.0 3.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain RhoGEF PF00621.20 CUU00411.1 - 0.063 13.5 7.6 0.73 10.1 0.0 4.4 4 0 0 4 4 4 0 RhoGEF domain STAR_dimer PF16544.5 CUU00411.1 - 0.067 12.8 0.0 23 4.7 0.0 3.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein DEDD_Tnp_IS110 PF01548.17 CUU00411.1 - 0.23 11.3 0.6 28 4.6 0.1 2.3 2 0 0 2 2 2 0 Transposase HS1_rep PF02218.15 CUU00411.1 - 4 7.9 6.4 1.3e+02 3.0 0.1 3.5 3 0 0 3 3 3 0 Repeat in HS1/Cortactin WD40 PF00400.32 CUU00412.1 - 2.6e-31 107.2 9.4 7.5e-05 23.4 0.0 10.4 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU00412.1 - 4.7e-19 68.5 0.0 0.002 18.4 0.0 7.5 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CUU00412.1 - 8.6e-07 28.6 0.0 0.0079 15.6 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain PD40 PF07676.12 CUU00412.1 - 7.6e-05 22.5 0.2 6.6 6.8 0.0 4.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CUU00412.1 - 0.00053 19.0 0.0 0.61 9.0 0.0 3.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CUU00412.1 - 0.00091 19.1 0.0 0.036 13.9 0.0 3.5 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 CUU00412.1 - 0.0098 15.0 0.1 2.3 7.2 0.0 3.2 3 1 1 4 4 4 1 VID27 C-terminal WD40-like domain DUF4875 PF16175.5 CUU00412.1 - 0.2 11.8 0.5 0.76 9.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4875) Nop14 PF04147.12 CUU00415.1 - 0.00068 18.0 46.7 0.00092 17.6 46.7 1.2 1 0 0 1 1 1 1 Nop14-like family DUF4775 PF16001.5 CUU00415.1 - 0.83 9.0 45.6 1 8.7 45.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) 7tm_1 PF00001.21 CUU00417.1 - 1.5e-18 67.1 13.9 1.9e-18 66.8 13.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CUU00417.1 - 0.0023 17.6 17.8 0.0023 17.6 17.8 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Pkinase PF00069.25 CUU00418.1 - 1.6e-36 126.1 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU00418.1 - 6.2e-17 61.7 0.0 7.9e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CUU00418.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF775 PF05603.12 CUU00419.1 - 4.6e-35 121.0 0.0 8.7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Ribosomal_L12 PF00542.19 CUU00419.1 - 5.3e-18 65.1 3.6 5.3e-18 65.1 3.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CUU00419.1 - 6.2e-08 32.2 1.3 1.2e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF775 PF05603.12 CUU00420.1 - 4.6e-35 121.0 0.0 8.7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Ribosomal_L12 PF00542.19 CUU00420.1 - 5.3e-18 65.1 3.6 5.3e-18 65.1 3.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CUU00420.1 - 6.2e-08 32.2 1.3 1.2e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain LETM1 PF07766.13 CUU00422.1 - 6e-56 189.7 2.1 7.7e-56 189.4 2.1 1.1 1 0 0 1 1 1 1 LETM1-like protein LETM1 PF07766.13 CUU00423.1 - 2.1e-86 289.6 8.0 2.1e-86 289.6 8.0 2.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 CUU00423.1 - 0.033 14.0 0.0 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 SAP domain DUF948 PF06103.11 CUU00423.1 - 0.11 12.7 6.8 0.03 14.6 2.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 CUU00423.1 - 1.1 9.3 4.6 0.61 10.1 1.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF747 PF05346.11 CUU00424.1 - 8.3e-39 133.9 0.3 8.3e-39 133.9 0.3 1.4 2 0 0 2 2 2 1 Eukaryotic membrane protein family tRNA-synt_2 PF00152.20 CUU00425.1 - 7.3e-67 225.7 0.0 1.1e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CUU00425.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SET PF00856.28 CUU00426.1 - 3.8e-23 82.7 0.0 1e-22 81.3 0.0 1.7 1 1 0 1 1 1 1 SET domain Chromo PF00385.24 CUU00426.1 - 5.5e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pre-SET PF05033.16 CUU00426.1 - 0.00071 20.2 9.4 0.17 12.5 4.1 3.3 2 1 0 3 3 3 2 Pre-SET motif Xpo1 PF08389.12 CUU00427.1 - 4.2e-23 82.1 1.0 4.2e-23 82.1 1.0 2.2 3 0 0 3 3 3 1 Exportin 1-like protein LRR_6 PF13516.6 CUU00430.1 - 4.3e-09 35.7 11.3 0.0028 17.6 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 CUU00430.1 - 0.0065 16.9 5.8 14 6.7 0.1 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 CUU00430.1 - 0.21 12.0 6.8 41 4.8 0.1 5.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Sof1 PF04158.14 CUU00431.1 - 3e-22 78.7 7.5 5.1e-22 77.9 7.5 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CUU00431.1 - 4.8e-17 62.0 0.2 5.6e-07 30.2 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU00431.1 - 8e-05 22.9 0.2 0.15 12.3 0.0 3.7 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CUU00431.1 - 0.00019 21.4 0.3 0.55 10.1 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CUU00431.1 - 0.0016 17.9 0.0 3.4 6.9 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain AnfO_nitrog PF09582.10 CUU00432.1 - 0.007 15.7 0.6 0.0084 15.5 0.6 1.1 1 0 0 1 1 1 1 Iron only nitrogenase protein AnfO (AnfO_nitrog) OpcA PF07239.11 CUU00432.1 - 0.072 12.8 0.1 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 Outer membrane protein OpcA AlkA_N PF06029.11 CUU00433.1 - 0.018 15.3 0.9 0.024 14.9 0.9 1.4 1 1 0 1 1 1 0 AlkA N-terminal domain Exo_endo_phos_2 PF14529.6 CUU00435.1 - 2.9e-09 36.8 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CUU00436.1 - 2.5e-09 37.0 0.1 3e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 CUU00440.1 - 6.2e-27 94.0 4.3 1.7e-12 47.7 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU00440.1 - 2.2e-23 82.3 1.9 1e-08 35.5 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU00440.1 - 6.6e-22 75.2 7.1 5.5e-05 23.3 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CUU00440.1 - 2e-21 75.4 11.7 0.0018 18.6 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CUU00440.1 - 1e-20 73.5 12.8 2.6e-05 24.4 0.5 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 CUU00440.1 - 7e-05 23.1 1.0 0.00015 22.1 1.0 1.5 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 CUU00441.1 - 4e-27 94.6 4.2 1.4e-12 48.0 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU00441.1 - 1.6e-23 82.7 2.1 8.8e-09 35.7 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU00441.1 - 3.5e-22 76.1 7.1 4.8e-05 23.4 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CUU00441.1 - 1.1e-21 76.3 11.7 0.0016 18.8 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CUU00441.1 - 5.4e-21 74.4 12.8 2.2e-05 24.6 0.5 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 CUU00441.1 - 6.2e-05 23.3 1.0 0.00013 22.3 1.0 1.5 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 CUU00442.1 - 3.9e-27 94.6 4.2 1.4e-12 48.0 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU00442.1 - 1.6e-23 82.7 2.1 8.8e-09 35.7 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU00442.1 - 3.4e-22 76.1 7.1 4.7e-05 23.5 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CUU00442.1 - 1.1e-21 76.3 11.7 0.0016 18.8 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CUU00442.1 - 4.9e-21 74.5 12.7 2.2e-05 24.6 0.5 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SOCS_box PF07525.16 CUU00442.1 - 5.9e-05 23.3 1.0 0.00013 22.3 1.0 1.5 1 0 0 1 1 1 1 SOCS box APG6_N PF17675.1 CUU00444.1 - 0.014 15.9 9.3 0.015 15.8 9.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 CUU00444.1 - 0.028 14.2 5.8 0.029 14.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 CUU00444.1 - 0.17 12.3 8.6 0.21 12.0 8.6 1.2 1 0 0 1 1 1 0 Cell division protein ZapB 7tm_1 PF00001.21 CUU00446.1 - 0.0049 16.2 2.9 0.0093 15.3 2.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 CUU00447.1 - 0.0049 16.2 2.9 0.0093 15.3 2.9 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Lectin_leg-like PF03388.13 CUU00450.1 - 2.2e-70 236.6 0.1 2.8e-70 236.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CUU00450.1 - 7e-09 36.0 2.4 9e-09 35.6 2.4 1.1 1 0 0 1 1 1 1 Bacterial lectin DUF5491 PF17595.2 CUU00450.1 - 0.0084 16.4 0.0 0.035 14.4 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5491) Lectin_legB PF00139.19 CUU00450.1 - 0.025 14.1 0.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Legume lectin domain RCR PF12273.8 CUU00450.1 - 1.4 9.6 3.5 28 5.4 1.7 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red zf-3CxxC PF13695.6 CUU00451.1 - 3.4e-28 98.0 0.2 6.9e-28 97.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding domain TPR_2 PF07719.17 CUU00454.1 - 3.8e-06 26.6 5.6 0.00036 20.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CUU00454.1 - 4.9e-06 26.1 1.6 0.00052 19.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CUU00454.1 - 0.00022 21.2 4.8 0.00059 19.9 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CUU00454.1 - 0.00035 20.8 0.1 0.00099 19.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU00454.1 - 0.0007 20.1 0.1 0.0017 18.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CUU00454.1 - 0.026 14.7 0.0 0.098 12.9 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CUU00454.1 - 0.22 11.7 2.5 1 9.5 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CUU00455.1 - 4.1e-09 35.9 4.0 0.002 18.1 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CUU00455.1 - 3.2e-07 30.0 6.3 0.00014 21.8 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CUU00455.1 - 1.3e-06 28.0 7.0 0.0035 17.1 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CUU00455.1 - 2.3e-05 24.4 2.4 0.25 11.8 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CUU00455.1 - 0.00012 22.5 0.2 0.00061 20.2 0.3 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CUU00455.1 - 0.001 19.3 0.3 0.0039 17.4 0.3 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CUU00455.1 - 0.0051 17.4 1.4 2.4 9.0 0.3 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CUU00455.1 - 0.0068 17.1 0.0 37 5.5 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CUU00455.1 - 0.03 14.4 0.4 2.1 8.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1955 PF09205.10 CUU00455.1 - 0.051 13.3 0.4 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) DUF3549 PF12069.8 CUU00455.1 - 0.052 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) TPR_2 PF07719.17 CUU00456.1 - 1.5e-06 27.9 7.6 0.0096 16.0 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CUU00456.1 - 3.2e-06 26.9 9.6 0.00048 20.1 1.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CUU00456.1 - 6.1e-05 22.7 7.3 0.023 14.5 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CUU00456.1 - 7.5e-05 23.0 3.5 0.0014 18.9 0.8 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU00456.1 - 0.00022 21.7 0.8 0.00039 20.9 0.7 1.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SMG1 PF15785.5 CUU00456.1 - 0.024 13.0 0.1 0.028 12.8 0.1 1.0 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Gag_p17 PF00540.18 CUU00456.1 - 0.025 14.6 1.0 0.039 13.9 0.2 1.7 2 1 0 2 2 2 0 gag gene protein p17 (matrix protein) TPR_10 PF13374.6 CUU00456.1 - 0.073 13.0 3.0 14 5.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CUU00456.1 - 0.088 13.2 0.7 22 5.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CUU00457.1 - 1.7e-05 24.7 4.8 0.00067 19.7 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CUU00457.1 - 1.8e-05 24.5 5.9 0.02 15.0 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CUU00457.1 - 5.3e-05 22.9 4.0 0.011 15.6 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat CHAD PF05235.14 CUU00457.1 - 0.0084 16.1 0.2 0.01 15.8 0.2 1.1 1 0 0 1 1 1 1 CHAD domain TPR_12 PF13424.6 CUU00457.1 - 0.0088 16.3 0.3 0.0088 16.3 0.3 3.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU00457.1 - 0.058 13.9 0.5 0.16 12.5 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CUU00457.1 - 0.093 13.6 3.8 42 5.3 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Uteroglobin PF01099.17 CUU00457.1 - 0.098 13.0 0.4 0.24 11.8 0.1 1.8 1 1 1 2 2 2 0 Uteroglobin family wnt PF00110.19 CUU00458.1 - 4.8e-61 207.0 10.9 4.5e-39 134.9 10.1 2.3 2 1 0 2 2 2 2 wnt family Cu2_monoox_C PF03712.15 CUU00459.1 - 2e-26 92.4 0.0 3.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 CUU00459.1 - 1.3e-15 57.8 0.1 2.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 CUU00459.1 - 6.6e-13 48.0 2.2 3.3e-08 33.1 0.1 5.1 5 0 0 5 5 5 2 NHL repeat SGL PF08450.12 CUU00459.1 - 0.043 13.4 0.0 0.3 10.6 0.0 2.2 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region SLAIN PF15301.6 CUU00460.1 - 1.4e-10 41.1 2.4 1.4e-10 41.1 2.4 1.6 1 1 0 1 1 1 1 SLAIN motif-containing family Ribosomal_S21 PF01165.20 CUU00461.1 - 1.5e-14 53.5 0.8 2.1e-14 53.0 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 SRPRB PF09439.10 CUU00465.1 - 3e-27 95.2 0.1 3.6e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CUU00465.1 - 7.1e-09 35.3 0.0 9.9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CUU00465.1 - 0.00051 19.9 0.0 0.00059 19.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein V-set PF07686.17 CUU00469.1 - 0.0065 16.6 0.1 2.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin V-set domain RabGAP-TBC PF00566.18 CUU00470.1 - 4.3e-37 127.9 0.0 8.5e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CUU00470.1 - 4.1e-13 49.2 0.3 5.7e-06 26.2 0.1 2.6 2 0 0 2 2 2 2 GRAM domain DUF2863 PF11062.8 CUU00470.1 - 0.076 11.4 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) GCP_N_terminal PF17681.1 CUU00471.1 - 1.3e-18 67.7 0.0 1.8e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF3067 PF11267.8 CUU00471.1 - 0.15 12.6 0.0 0.22 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) DCA16 PF15349.6 CUU00473.1 - 0.095 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 IFT46_B_C PF12317.8 CUU00476.1 - 3.3e-84 281.9 1.5 4.6e-84 281.4 1.5 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal WD40 PF00400.32 CUU00477.1 - 0.19 12.6 8.1 1.6 9.7 0.1 3.7 3 1 0 3 3 3 0 WD domain, G-beta repeat PLAT PF01477.23 CUU00481.1 - 6e-48 162.2 1.1 1.3e-14 54.8 0.0 3.7 4 0 0 4 4 4 3 PLAT/LH2 domain ATS3 PF06232.11 CUU00481.1 - 0.08 12.9 0.0 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Embryo-specific protein 3, (ATS3) PLAT PF01477.23 CUU00482.1 - 1e-55 187.3 1.1 5.2e-22 78.6 0.0 4.4 4 0 0 4 4 4 4 PLAT/LH2 domain Lgl_C PF08596.10 CUU00485.1 - 0.0064 15.2 0.3 0.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal 3HBOH PF10605.9 CUU00486.1 - 0.014 13.7 0.0 0.02 13.2 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Arrestin_N PF00339.29 CUU00486.1 - 0.043 13.9 0.5 0.097 12.7 0.2 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain EAF PF09816.9 CUU00486.1 - 0.16 12.4 1.6 1.3 9.5 1.6 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription elongation factor SHIPPO-rpt PF07004.12 CUU00486.1 - 0.3 12.1 8.8 0.77 10.8 0.1 3.8 3 1 0 3 3 3 0 Sperm-tail PG-rich repeat adh_short PF00106.25 CUU00487.1 - 2.7e-23 82.4 0.0 3.3e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CUU00487.1 - 5.4e-15 55.6 0.0 1.7e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CUU00487.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CUU00487.1 - 7.5e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 CUU00489.1 - 2.5e-11 43.3 0.1 1.2e-09 37.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CUU00489.1 - 3.6e-07 30.1 0.7 0.00014 21.6 0.7 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CUU00489.1 - 1.3e-05 25.9 0.0 1.9e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 CUU00489.1 - 0.015 14.3 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 CUU00489.1 - 0.064 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PWI PF01480.17 CUU00490.1 - 2.8e-14 53.2 2.8 2.9e-14 53.1 0.2 2.3 2 0 0 2 2 2 1 PWI domain Tti2 PF10521.9 CUU00490.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.5 3 0 0 3 3 3 0 Tti2 family Clat_adaptor_s PF01217.20 CUU00491.1 - 5.8e-16 58.7 1.9 1.2e-11 44.7 0.4 2.2 1 1 1 2 2 2 2 Clathrin adaptor complex small chain DUF2207 PF09972.9 CUU00494.1 - 1.9e-07 30.3 0.0 0.00014 20.8 0.3 2.6 2 1 0 2 2 2 2 Predicted membrane protein (DUF2207) Prominin PF05478.11 CUU00494.1 - 2.1e-05 22.7 13.6 0.017 13.1 0.0 3.5 3 1 0 3 3 3 2 Prominin SUR7 PF06687.12 CUU00494.1 - 4.5e-05 23.2 0.0 0.032 13.8 1.4 2.9 3 1 0 3 3 3 1 SUR7/PalI family Shisa PF13908.6 CUU00494.1 - 0.0028 17.9 0.0 0.0028 17.9 0.0 3.4 3 1 1 4 4 4 1 Wnt and FGF inhibitory regulator DUF898 PF05987.13 CUU00494.1 - 0.023 13.7 1.8 0.2 10.7 0.5 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF898) Calcyon PF06387.11 CUU00494.1 - 0.036 14.1 0.0 0.036 14.1 0.0 2.3 3 0 0 3 3 2 0 D1 dopamine receptor-interacting protein (calcyon) MTBP_N PF14918.6 CUU00494.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 MDM2-binding Herpes_gE PF02480.16 CUU00494.1 - 0.16 10.7 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MLANA PF14991.6 CUU00494.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.6 6 0 0 6 6 3 0 Protein melan-A NPV_P10 PF05531.12 CUU00494.1 - 0.2 12.1 6.0 0.44 11.0 0.1 3.8 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein MIG-14_Wnt-bd PF06664.12 CUU00494.1 - 0.21 10.8 9.0 0.49 9.6 1.0 3.3 4 0 0 4 4 4 0 Wnt-binding factor required for Wnt secretion Orthoreo_P10 PF07204.11 CUU00494.1 - 0.28 11.2 0.0 0.28 11.2 0.0 3.7 5 0 0 5 5 5 0 Orthoreovirus membrane fusion protein p10 DUF2408 PF10303.9 CUU00494.1 - 0.3 11.7 2.7 6 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) EphA2_TM PF14575.6 CUU00494.1 - 1.7 9.6 9.3 2.3 9.2 0.0 4.3 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain DUF4022 PF13214.6 CUU00494.1 - 3.8 7.9 16.2 1.4 9.3 0.2 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF4022) DUF4834 PF16118.5 CUU00494.1 - 8.9 7.4 0.0 8.9 7.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Endonuclease_5 PF04493.14 CUU97319.1 - 6.4e-05 22.7 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V Endonuclease_5 PF04493.14 CUU97320.1 - 0.00099 18.8 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease V DEFB136 PF17333.2 CUU97320.1 - 0.2 11.6 1.3 3.1 7.8 0.8 2.5 1 1 1 2 2 2 0 Beta defensin 136 DUF4061 PF13270.6 CUU97323.1 - 6.4e-25 87.3 1.1 8.3e-25 86.9 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4061) Pkinase PF00069.25 CUU97324.1 - 4.4e-33 114.8 0.0 5.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU97324.1 - 7.5e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_2 PF13465.6 CUU97326.1 - 2.6e-26 90.8 31.2 1.7e-08 34.5 0.6 5.5 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 CUU97326.1 - 1.2e-21 75.8 37.8 1.3e-05 25.3 0.4 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU97326.1 - 2.9e-15 55.7 38.2 0.005 17.6 0.1 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-met PF12874.7 CUU97326.1 - 6.3e-10 39.1 23.0 0.051 14.0 1.0 5.8 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CUU97326.1 - 7.2e-10 38.9 12.9 0.0096 16.2 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CUU97326.1 - 1.2e-07 31.6 31.0 0.013 15.5 2.3 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CUU97326.1 - 4.4e-05 23.5 8.9 0.47 10.6 2.0 4.1 3 2 1 4 4 4 2 Zinc ribbon domain zf-C2HE PF16278.5 CUU97326.1 - 0.00016 22.0 30.5 0.33 11.4 2.2 5.7 3 1 3 6 6 6 3 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 CUU97326.1 - 0.0023 18.2 5.4 1.5 9.2 0.4 3.5 1 1 2 3 3 3 2 BolA-like protein Scramblase PF03803.15 CUU97326.1 - 0.029 13.7 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 Scramblase zf-C2H2_3rep PF18868.1 CUU97326.1 - 0.068 13.9 13.6 4 8.1 1.2 3.9 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 CUU97326.1 - 0.17 11.8 5.7 3.5 7.5 0.0 4.2 3 1 2 5 5 5 0 C2H2 type zinc-finger (1 copy) C1_4 PF07975.12 CUU97326.1 - 0.6 10.4 18.3 4.6 7.6 0.2 3.9 1 1 1 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 CUU97326.1 - 0.91 9.5 12.8 27 4.8 0.4 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 CUU97326.1 - 1 9.7 22.1 11 6.4 1.3 5.1 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CUU97326.1 - 3.4 7.5 27.6 1.8 8.4 1.3 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type GAGA PF09237.11 CUU97326.1 - 4.3 7.2 9.7 6.9 6.6 0.1 3.6 1 1 1 3 3 3 0 GAGA factor zf-trcl PF13451.6 CUU97326.1 - 5.2 7.1 12.9 0.12 12.3 1.4 3.2 4 0 0 4 4 4 0 Probable zinc-ribbon domain PDZ PF00595.24 CUU97327.1 - 8e-11 42.2 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LIM PF00412.22 CUU97327.1 - 6.1e-09 36.0 3.5 9.6e-09 35.4 3.5 1.3 1 0 0 1 1 1 1 LIM domain PDZ_6 PF17820.1 CUU97327.1 - 3.2e-06 26.9 0.0 7.9e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 PDZ domain DUF4749 PF15936.5 CUU97327.1 - 0.00013 23.0 0.2 0.00037 21.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4749) EutA PF06277.11 CUU97327.1 - 0.019 13.9 0.1 0.029 13.2 0.0 1.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA PDZ_2 PF13180.6 CUU97327.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain VATC PF18716.1 CUU97327.1 - 0.4 10.6 5.5 0.7 9.8 2.9 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain RhoGAP-FF1 PF16512.5 CUU97328.1 - 0.018 15.7 0.1 0.029 15.0 0.1 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain SbsC_C PF18058.1 CUU97328.1 - 0.043 14.1 0.2 0.057 13.7 0.2 1.2 1 0 0 1 1 1 0 SbsC C-terminal domain Annexin PF00191.20 CUU97329.1 - 4.8e-09 36.1 0.2 7.7e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Annexin UQ_con PF00179.26 CUU97331.1 - 3.5e-33 114.2 0.0 4.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CUU97331.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DNA_pol_delta_4 PF04081.13 CUU97332.1 - 0.004 17.5 0.3 0.008 16.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Speriolin_C PF15059.6 CUU97332.1 - 0.0041 17.3 1.1 0.0046 17.1 1.1 1.1 1 0 0 1 1 1 1 Speriolin C-terminus Fer4_16 PF13484.6 CUU97332.1 - 0.17 12.8 0.7 0.28 12.1 0.7 1.7 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fn3-like PF14310.6 CUU97336.1 - 0.092 12.9 0.0 8.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III-like domain zf-C2H2_4 PF13894.6 CUU97338.1 - 2.5e-08 34.1 32.2 0.0032 18.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CUU97338.1 - 2.6e-05 24.4 5.0 0.00096 19.5 0.1 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CUU97338.1 - 0.00066 19.9 0.0 0.00066 19.9 0.0 4.4 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CUU97338.1 - 0.01 16.1 25.9 0.64 10.3 0.1 4.2 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CUU97338.1 - 0.013 15.5 0.1 0.013 15.5 0.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CUU97338.1 - 0.015 15.6 19.7 1.2 9.5 5.6 3.4 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 CUU97338.1 - 0.019 14.8 9.4 2.2 8.2 0.2 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CUU97338.1 - 0.049 14.0 0.3 0.049 14.0 0.3 4.1 5 0 0 5 5 3 0 Zinc-finger of C2H2 type DUF4253 PF14062.6 CUU97338.1 - 0.075 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Phytochelatin PF05023.14 CUU97338.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase DUF2256 PF10013.9 CUU97338.1 - 2.1 8.5 7.9 58 3.9 0.0 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 CUU97338.1 - 3.9 7.2 18.0 3.1 7.5 0.0 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 CUU97338.1 - 8.5 7.0 24.8 0.18 12.3 1.9 4.7 3 1 1 4 4 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CUU97338.1 - 8.7 6.6 16.7 17 5.6 0.0 4.3 4 1 0 4 4 4 0 Zinc ribbon domain NSP2_assoc PF14758.6 CUU97341.1 - 0.0079 16.6 5.1 0.0084 16.5 3.8 1.6 1 1 1 2 2 2 1 Non-essential region of nsp2 of arterivirus polyprotein Dicty_REP PF05086.12 CUU97341.1 - 0.27 9.2 1.6 0.25 9.3 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mif2_N PF15624.6 CUU97341.1 - 0.3 11.8 11.4 0.52 11.0 11.3 1.5 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Macoilin PF09726.9 CUU97341.1 - 0.48 8.9 4.8 0.47 9.0 4.8 1.1 1 0 0 1 1 1 0 Macoilin family LRR_4 PF12799.7 CUU97342.1 - 2.1e-16 59.8 18.0 1.4e-09 38.1 1.7 4.4 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CUU97342.1 - 9e-15 54.6 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CUU97342.1 - 7.2e-10 38.5 4.9 0.0029 17.3 0.0 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CUU97342.1 - 1.8e-05 24.6 7.5 4.4 8.3 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 CUU97342.1 - 0.0015 18.4 14.2 0.075 13.1 0.9 5.1 5 0 0 5 5 5 2 Leucine Rich repeat FRQ PF09421.10 CUU97342.1 - 1.5 6.8 12.6 2 6.3 12.6 1.1 1 0 0 1 1 1 0 Frequency clock protein BUD22 PF09073.10 CUU97342.1 - 3 7.1 22.4 4.2 6.6 22.4 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CUU97342.1 - 4.5 6.6 23.2 8.2 5.8 23.2 1.4 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 CUU97342.1 - 6.6 6.2 16.9 12 5.3 16.9 1.4 1 0 0 1 1 1 0 PPP4R2 TPR_1 PF00515.28 CUU97344.1 - 1.6e-29 100.4 10.3 4.2e-07 29.5 0.1 7.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CUU97344.1 - 1.3e-27 93.7 9.4 0.00013 21.8 0.0 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CUU97344.1 - 1.4e-23 81.0 6.2 0.014 15.6 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 CUU97344.1 - 2.2e-15 56.1 0.7 0.005 16.5 0.0 6.5 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 CUU97344.1 - 3.2e-15 56.5 4.0 4.3e-05 24.1 0.0 5.0 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CUU97344.1 - 6.9e-14 51.4 9.7 0.036 14.9 0.1 7.3 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CUU97344.1 - 3.5e-13 48.9 3.3 0.12 12.8 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CUU97344.1 - 2e-12 46.2 1.5 0.026 14.5 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CUU97344.1 - 4.8e-11 42.6 7.6 5.9e-05 23.1 0.4 5.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CUU97344.1 - 7.4e-11 42.2 7.8 0.0038 17.5 0.4 6.1 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CUU97344.1 - 2e-08 34.6 1.2 0.037 14.5 0.1 6.2 5 1 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 CUU97344.1 - 2.9e-05 23.8 1.0 2.6 7.7 0.0 4.9 5 1 0 5 5 4 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 CUU97344.1 - 8.7e-05 21.9 0.4 0.099 11.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CUU97344.1 - 0.00022 21.2 1.2 8.4 6.5 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CUU97344.1 - 0.00095 19.7 7.4 2.4 9.0 0.1 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CUU97344.1 - 0.0031 16.9 0.1 0.053 12.9 0.1 2.8 4 0 0 4 4 4 1 MalT-like TPR region TPR_21 PF09976.9 CUU97344.1 - 0.0032 17.2 1.0 0.22 11.2 0.0 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain NRBF2_MIT PF17169.4 CUU97344.1 - 0.039 14.2 0.1 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 Mitofilin PF09731.9 CUU97344.1 - 0.056 12.3 17.0 0.12 11.2 17.0 1.6 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF483 PF04467.12 CUU97344.1 - 0.068 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF483) SAPS PF04499.15 CUU97344.1 - 0.15 10.8 7.0 0.23 10.2 7.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TPR_10 PF13374.6 CUU97344.1 - 0.19 11.7 3.0 40 4.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat HEAT_2 PF13646.6 CUU97345.1 - 3.5e-13 49.8 22.0 2.3e-07 31.1 0.4 7.3 5 3 1 7 7 7 4 HEAT repeats HEAT PF02985.22 CUU97345.1 - 3.9e-12 45.3 32.3 0.0026 17.9 0.2 10.6 12 0 0 12 12 12 4 HEAT repeat Cnd1 PF12717.7 CUU97345.1 - 0.0044 17.1 5.3 0.058 13.4 0.0 3.9 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CUU97345.1 - 0.064 13.2 1.3 62 3.6 0.1 4.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain DUF3385 PF11865.8 CUU97345.1 - 0.074 13.0 0.0 8.4 6.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 CUU97345.1 - 0.12 10.9 5.2 22 3.4 0.0 4.0 4 0 0 4 4 4 0 Adaptin N terminal region HEAT_PBS PF03130.16 CUU97345.1 - 0.66 10.8 0.0 0.66 10.8 0.0 4.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat ArfGap PF01412.18 CUU97346.1 - 4.7e-32 110.5 0.1 3e-31 107.9 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CUU97346.1 - 9.3e-17 61.5 4.2 2.2e-16 60.3 4.2 1.6 1 0 0 1 1 1 1 BAR domain of APPL family SH3_1 PF00018.28 CUU97346.1 - 2.5e-10 39.8 0.0 6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CUU97346.1 - 5.3e-07 29.2 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 CUU97346.1 - 9.1e-07 29.4 0.1 2.3e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank PF00023.30 CUU97346.1 - 8.8e-06 25.9 2.9 0.003 17.9 0.1 3.0 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.6 CUU97346.1 - 1.2e-05 25.5 0.2 0.0031 17.8 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CUU97346.1 - 2e-05 25.1 0.0 7.7e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) BAR PF03114.18 CUU97346.1 - 6.9e-05 22.6 3.0 0.00018 21.2 3.0 1.7 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CUU97346.1 - 9.9e-05 22.1 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 CUU97346.1 - 0.00034 20.8 0.1 0.013 15.9 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CUU97346.1 - 0.0012 19.4 0.2 0.0058 17.2 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_3 PF14593.6 CUU97346.1 - 0.041 14.0 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 CUU97346.1 - 0.066 13.5 0.1 0.41 11.0 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 CUU97346.1 - 0.098 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain UPF0193 PF05250.11 CUU97346.1 - 0.48 10.2 3.2 0.75 9.6 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) RRM_1 PF00076.22 CUU97347.1 - 3.5e-12 46.0 0.0 6.7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CUU97347.1 - 0.29 11.4 1.4 5.4 7.2 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter TFIIA PF03153.13 CUU97347.1 - 1.9 8.4 16.1 0.41 10.6 10.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 CUU97348.1 - 7.5e-52 176.7 28.5 9.8e-52 176.3 28.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF4748 PF15932.5 CUU97348.1 - 0.14 12.0 1.1 0.2 11.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Serinc PF03348.15 CUU97349.1 - 2.3e-12 46.6 2.5 3.7e-12 45.9 2.5 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ribosom_S12_S23 PF00164.25 CUU97349.1 - 0.00094 18.8 1.4 2.9 7.5 0.0 3.7 4 0 0 4 4 4 2 Ribosomal protein S12/S23 DUF2732 PF10809.8 CUU97349.1 - 0.0013 18.5 4.6 0.43 10.5 0.2 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2732) Cid2 PF09774.9 CUU97349.1 - 0.0093 16.4 4.2 0.57 10.6 0.5 2.2 2 0 0 2 2 2 2 Caffeine-induced death protein 2 Chorion_2 PF03964.15 CUU97349.1 - 0.12 13.2 1.1 26 5.7 0.1 2.4 2 0 0 2 2 2 0 Chorion family 2 ProRS-C_1 PF09180.11 CUU97349.1 - 0.17 12.1 1.6 20 5.5 0.1 2.5 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal CRF PF00473.17 CUU97349.1 - 0.55 10.3 9.8 5.7 7.1 1.5 2.8 2 0 0 2 2 2 0 Corticotropin-releasing factor family DUF719 PF05334.13 CUU97349.1 - 0.72 10.0 4.8 11 6.1 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TetR_C_24 PF17932.1 CUU97349.1 - 4.2 7.7 8.6 6 7.2 0.8 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain JTB PF05439.12 CUU97350.1 - 1.9e-12 47.2 2.9 4.3e-12 46.1 2.9 1.6 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Vma12 PF11712.8 CUU97350.1 - 0.0047 17.0 0.7 10 6.2 0.0 3.3 3 0 0 3 3 3 2 Endoplasmic reticulum-based factor for assembly of V-ATPase Ni_hydr_CYTB PF01292.20 CUU97350.1 - 0.042 13.4 6.8 2.1 7.9 0.7 2.7 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF3278 PF11683.8 CUU97350.1 - 0.099 12.7 1.2 0.33 11.0 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3278) Spike_NTD PF16451.5 CUU97350.1 - 0.57 9.5 3.2 15 4.9 0.2 2.2 2 0 0 2 2 2 0 Spike glycoprotein N-terminal domain DUF565 PF04483.12 CUU97352.1 - 0.0085 16.6 0.2 0.022 15.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF565) zf-C4 PF00105.18 CUU97354.1 - 1.5e-30 105.5 19.5 2.6e-30 104.7 19.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CUU97354.1 - 0.042 13.4 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor zf-P11 PF03854.14 CUU97354.1 - 1.2 8.8 5.9 2.7 7.7 5.9 1.6 1 0 0 1 1 1 0 P-11 zinc finger Pkinase PF00069.25 CUU97355.1 - 1.3e-13 51.0 0.0 1.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 CUU97355.1 - 1.4e-07 32.1 5.2 0.33 11.9 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 CUU97355.1 - 0.12 11.6 0.0 6.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase RRM_1 PF00076.22 CUU97356.1 - 5.8e-22 77.3 0.5 9.2e-14 51.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CUU97356.1 - 1.5e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_3 PF08777.11 CUU97356.1 - 0.00084 19.3 0.2 2.4 8.3 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 CUU97356.1 - 0.0097 16.0 0.0 0.086 13.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif Nab6_mRNP_bdg PF10567.9 CUU97356.1 - 0.42 10.1 1.9 8.6 5.7 0.0 2.6 3 0 0 3 3 3 0 RNA-recognition motif UIM PF02809.20 CUU97357.1 - 5.2e-13 47.9 6.8 3.5e-05 23.4 0.1 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif VWA_2 PF13519.6 CUU97357.1 - 1.4e-12 48.2 0.1 9.5e-12 45.5 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 CUU97357.1 - 0.00013 21.8 0.3 0.00023 21.0 0.3 1.4 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 CUU97357.1 - 0.0028 17.4 0.4 0.0028 17.4 0.4 3.0 4 0 0 4 4 4 1 RAP80 N-terminal ubiquitin interaction motif AAA_6 PF12774.7 CUU97358.1 - 1.9e-156 520.1 0.0 1.2e-155 517.4 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CUU97358.1 - 2.2e-128 428.8 13.3 2.2e-128 428.8 13.3 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CUU97358.1 - 2.7e-107 358.5 0.0 6.1e-107 357.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CUU97358.1 - 4.3e-97 324.5 0.0 8.9e-97 323.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CUU97358.1 - 9.8e-88 293.0 1.6 9.8e-88 293.0 1.6 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CUU97358.1 - 2.2e-69 232.6 1.6 2.1e-67 226.2 0.0 3.6 5 0 0 5 5 5 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CUU97358.1 - 5.1e-60 202.0 0.5 3.7e-59 199.2 0.0 2.7 2 1 1 3 3 3 1 Dynein heavy chain AAA lid domain MT PF12777.7 CUU97358.1 - 1.3e-50 172.4 3.5 1.3e-50 172.4 3.5 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CUU97358.1 - 2.2e-45 153.6 0.0 3.6e-43 146.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CUU97358.1 - 7.7e-32 110.1 0.1 5.3e-31 107.4 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CUU97358.1 - 9.7e-18 64.2 0.6 1.3e-15 57.4 0.3 3.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CUU97358.1 - 5.8e-14 52.3 0.0 0.00086 19.3 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 CUU97358.1 - 0.00078 19.9 0.5 0.4 11.1 0.1 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CUU97358.1 - 0.011 16.3 1.2 1.4 9.4 0.0 4.5 4 0 0 4 4 4 0 AAA domain MDMPI_N PF11716.8 CUU97358.1 - 0.23 12.1 1.3 0.64 10.7 1.3 1.7 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Fur_reg_FbpB PF13040.6 CUU97358.1 - 2.3 7.8 7.4 11 5.6 1.9 3.6 3 0 0 3 3 3 0 Fur-regulated basic protein B AAA_28 PF13521.6 CUU97358.1 - 6.4 7.0 6.1 57 3.9 0.0 4.5 5 0 0 5 5 4 0 AAA domain Abhydrolase_6 PF12697.7 CUU97359.1 - 7.5e-05 23.4 0.0 0.00035 21.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CUU97359.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 CUU97359.1 - 0.021 13.5 0.1 0.05 12.3 0.0 1.4 1 1 0 1 1 1 0 Ndr family UPF0227 PF05728.12 CUU97359.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 CUU97359.1 - 0.067 12.4 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-U1 PF06220.12 CUU97360.1 - 2.2e-20 72.1 7.2 3e-20 71.7 7.2 1.2 1 0 0 1 1 1 1 U1 zinc finger Methyltransf_25 PF13649.6 CUU97361.1 - 1.3e-08 35.5 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CUU97361.1 - 9.1e-08 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CUU97361.1 - 2.5e-07 31.2 0.0 1.5e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CUU97361.1 - 9.6e-06 25.5 0.1 2.4e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CUU97361.1 - 1.8e-05 24.4 0.2 3.2e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CUU97361.1 - 2e-05 24.5 0.0 0.00013 21.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CUU97361.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CUU97361.1 - 0.011 14.7 0.1 0.023 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CUU97361.1 - 0.014 16.1 0.0 0.039 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CUU97361.1 - 0.095 12.1 0.5 0.33 10.3 0.5 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 CUU97361.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TMEM51 PF15345.6 CUU97365.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 Ion_trans PF00520.31 CUU97365.1 - 0.076 12.2 0.0 0.076 12.2 0.0 1.0 1 0 0 1 1 1 0 Ion transport protein SH2 PF00017.24 CUU97366.1 - 5.7e-22 77.6 0.1 7.3e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 SH2 domain Exo_endo_phos_2 PF14529.6 CUU97368.1 - 7.7e-12 45.1 0.1 1.3e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CUU97368.1 - 0.0048 16.4 0.0 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF4459 PF14673.6 CUU97368.1 - 0.14 12.1 0.0 30 4.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4459) Gelsolin PF00626.22 CUU97371.1 - 2e-23 82.1 0.0 2.4e-12 46.6 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Gelsolin PF00626.22 CUU97372.1 - 1.2e-22 79.6 0.0 2.5e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Gelsolin PF00626.22 CUU97373.1 - 2.5e-09 36.9 0.0 4e-06 26.6 0.0 3.4 3 1 0 3 3 3 2 Gelsolin repeat Gelsolin PF00626.22 CUU97374.1 - 8.2e-09 35.3 0.1 1.4e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 Gelsolin repeat Gelsolin PF00626.22 CUU97375.1 - 8.2e-09 35.3 0.1 1.4e-06 28.1 0.0 3.1 3 0 0 3 3 3 2 Gelsolin repeat HTH_24 PF13412.6 CUU97377.1 - 0.026 14.1 0.0 0.098 12.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CUU97377.1 - 0.031 14.1 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_AraC PF00165.23 CUU97377.1 - 0.15 12.2 0.0 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family SMAP PF15477.6 CUU97378.1 - 4.6e-12 46.7 0.5 4.6e-12 46.7 0.5 2.3 2 0 0 2 2 2 1 Small acidic protein family MAS20 PF02064.15 CUU97378.1 - 0.95 9.6 6.7 1.5 8.9 6.7 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor EF-hand_7 PF13499.6 CUU97379.1 - 5.3e-05 23.6 0.0 0.042 14.3 0.0 1.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CUU97379.1 - 0.00052 19.7 0.3 0.004 17.0 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CUU97379.1 - 0.00052 19.4 0.0 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 EF hand Methyltransf_31 PF13847.6 CUU97380.1 - 7.3 6.4 7.7 0.76 9.6 1.9 2.3 2 1 1 3 3 3 0 Methyltransferase domain Claudin_3 PF06653.11 CUU97383.1 - 0.0021 18.0 10.4 0.0061 16.5 10.4 1.7 1 1 0 1 1 1 1 Tight junction protein, Claudin-like DUF2127 PF09900.9 CUU97383.1 - 0.0036 17.6 0.8 0.0036 17.6 0.8 1.9 3 0 0 3 3 3 1 Predicted membrane protein (DUF2127) SpoVT_C PF15714.5 CUU97385.1 - 2.5 8.2 8.5 0.34 11.0 3.6 2.1 2 1 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Btz PF09405.10 CUU97386.1 - 0.044 14.0 0.1 0.044 14.0 0.1 1.7 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding DUF4065 PF13274.6 CUU97386.1 - 0.11 13.4 0.4 0.26 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) E1-E2_ATPase PF00122.20 CUU97387.1 - 3e-29 101.8 0.0 3e-29 101.8 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CUU97387.1 - 4.4e-20 72.9 0.0 2.1e-12 47.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CUU97387.1 - 2.1e-07 30.9 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CUU97387.1 - 0.19 11.5 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HTH_48 PF17906.1 CUU97388.1 - 1.4e-07 31.5 0.4 2e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 HTH domain in Mos1 transposase DUF763 PF05559.11 CUU97388.1 - 0.12 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) EST1_DNA_bind PF10373.9 CUU97390.1 - 1.2e-05 25.0 1.5 2e-05 24.2 0.2 2.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain p450 PF00067.22 CUU97392.1 - 2.4e-39 135.4 0.0 2.9e-21 75.7 0.0 3.4 3 1 0 3 3 3 3 Cytochrome P450 oligo_HPY PF08352.12 CUU97393.1 - 0.2 12.2 0.6 5 7.7 0.1 2.7 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-C2H2 PF00096.26 CUU97395.1 - 1.9e-09 37.5 8.1 6.7e-06 26.3 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU97395.1 - 2e-09 37.5 6.7 1.6e-05 25.4 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU97395.1 - 4e-07 30.2 9.2 0.0018 18.6 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 CUU97395.1 - 1.1e-05 25.7 2.7 0.0019 18.5 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CUU97395.1 - 2.2e-05 24.7 2.2 0.00021 21.6 2.8 1.8 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CUU97395.1 - 4.2e-05 23.7 5.0 0.0066 16.7 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CUU97395.1 - 0.00013 21.9 3.4 0.0026 17.7 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CUU97395.1 - 0.00019 21.6 3.4 0.0024 18.1 0.2 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 CUU97395.1 - 0.0008 19.4 0.3 1 9.5 0.0 2.5 2 0 0 2 2 2 2 BED zinc finger DUF4764 PF15961.5 CUU97395.1 - 0.0041 15.9 0.9 0.65 8.6 0.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 CUU97395.1 - 0.005 16.6 4.5 0.082 12.7 0.1 2.8 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 CUU97395.1 - 0.0087 15.9 1.2 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-AN1 PF01428.16 CUU97395.1 - 0.02 15.1 0.7 5.5 7.2 0.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-DNL PF05180.12 CUU97395.1 - 0.02 14.8 4.2 0.1 12.6 3.1 2.4 1 1 0 1 1 1 0 DNL zinc finger Zn-C2H2_12 PF18112.1 CUU97395.1 - 0.035 14.6 3.7 2 9.0 1.1 3.5 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 CUU97395.1 - 0.037 14.7 0.5 0.08 13.6 0.5 1.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 CUU97395.1 - 0.039 12.5 1.3 0.067 11.7 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF629) CpXC PF14353.6 CUU97395.1 - 0.056 13.5 0.7 0.19 11.8 0.7 1.7 1 1 0 1 1 1 0 CpXC protein HypA PF01155.19 CUU97395.1 - 0.06 13.4 0.2 0.078 13.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sprouty PF05210.13 CUU97395.1 - 0.06 13.7 0.9 0.067 13.6 0.9 1.1 1 0 0 1 1 1 0 Sprouty protein (Spry) zf_ZIC PF18366.1 CUU97395.1 - 0.1 12.7 0.3 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf_UBZ PF18439.1 CUU97395.1 - 0.1 12.2 1.8 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 CUU97395.1 - 0.21 11.7 3.9 3.9 7.6 0.4 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RVT PF13966.6 CUU97401.1 - 0.08 13.7 0.5 0.11 13.2 0.5 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Pkinase PF00069.25 CUU97403.1 - 7.3e-39 133.7 0.0 8.9e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU97403.1 - 9e-12 44.8 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CUU97403.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CUU97403.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CUU97403.1 - 0.087 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pro-kuma_activ PF09286.11 CUU97404.1 - 0.077 13.3 0.0 0.11 12.8 0.0 1.3 1 1 0 1 1 1 0 Pro-kumamolisin, activation domain VHS PF00790.19 CUU97407.1 - 1.6e-20 73.4 0.0 4.1e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CUU97407.1 - 6.4e-16 57.7 0.1 6.4e-16 57.7 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CUU97407.1 - 2.9e-13 49.3 0.0 6.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CUU97407.1 - 2e-11 43.5 0.0 5.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 CUU97407.1 - 6e-05 22.7 2.0 0.00017 21.3 2.0 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif SH3_10 PF17902.1 CUU97407.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 SH3 domain DUF5045 PF16464.5 CUU97408.1 - 0.035 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) zf-RVT PF13966.6 CUU97412.1 - 0.11 13.2 2.8 0.14 12.9 2.8 1.4 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DP PF08781.10 CUU97414.1 - 1.7e-36 125.2 6.2 1.3e-23 83.4 0.0 2.4 2 0 0 2 2 2 2 Transcription factor DP E2F_TDP PF02319.20 CUU97414.1 - 1.4e-19 69.9 0.1 3.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain CagY_M PF07337.11 CUU97414.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 DC-EC Repeat EGF_alliinase PF04863.13 CUU97414.1 - 3.5 8.1 5.2 1.7 9.1 2.3 2.0 2 0 0 2 2 2 0 Alliinase EGF-like domain Tyr-DNA_phospho PF06087.12 CUU97415.1 - 2.8e-116 388.9 0.0 3.4e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-CCHH PF10283.9 CUU97415.1 - 1.7e-09 37.5 5.4 1.7e-09 37.5 5.4 2.1 2 0 0 2 2 2 1 PBZ domain zf-rbx1 PF12678.7 CUU97416.1 - 0.00035 20.8 0.2 0.00073 19.8 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CUU97416.1 - 0.00037 20.8 0.2 0.00074 19.8 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CUU97416.1 - 0.0078 16.2 0.3 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CUU97416.1 - 0.018 14.6 0.6 0.038 13.6 0.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CUU97416.1 - 0.025 14.3 0.1 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CUU97416.1 - 0.029 14.2 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CUU97416.1 - 0.032 14.4 0.3 0.061 13.5 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Haspin_kinase PF12330.8 CUU97417.1 - 9.9e-51 172.8 0.0 1.2e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 CUU97417.1 - 7.3e-07 29.3 2.8 0.032 14.1 0.2 3.0 2 2 0 2 2 2 2 Phosphotransferase enzyme family RHH_4 PF13467.6 CUU97417.1 - 0.027 14.3 0.1 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain CSM2 PF16834.5 CUU97417.1 - 0.028 14.0 0.0 9.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Shu complex component Csm2, DNA-binding HTH_Mga PF08280.11 CUU97417.1 - 0.044 13.8 0.2 16 5.6 0.0 2.6 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain IL17 PF06083.11 CUU97417.1 - 0.046 14.2 0.0 22 5.6 0.0 2.6 2 0 0 2 2 2 0 Interleukin-17 DUF1615 PF07759.12 CUU97417.1 - 0.054 12.7 0.1 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1615) IFT57 PF10498.9 CUU97418.1 - 1.2e-92 310.6 4.4 3.5e-92 309.2 4.4 1.6 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF773 PF05600.12 CUU97418.1 - 0.0029 16.4 2.2 0.0044 15.8 2.2 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 Spc7 PF08317.11 CUU97418.1 - 0.012 14.5 7.3 0.018 13.9 7.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YkyA PF10368.9 CUU97418.1 - 0.023 14.4 6.3 0.043 13.5 6.3 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ARA70 PF12489.8 CUU97418.1 - 0.03 14.5 6.9 0.3 11.3 5.9 2.6 2 1 0 2 2 2 0 Nuclear coactivator Hrs_helical PF12210.8 CUU97418.1 - 0.046 14.3 4.2 0.13 12.8 0.9 2.6 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Transcrip_act PF04949.13 CUU97418.1 - 0.059 13.3 4.1 0.11 12.3 4.1 1.4 1 0 0 1 1 1 0 Transcriptional activator DUF1043 PF06295.12 CUU97418.1 - 0.084 12.9 5.4 4.3 7.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Peptidase_M3_N PF08439.10 CUU97418.1 - 0.15 12.3 4.0 0.13 12.5 0.5 2.5 2 0 0 2 2 2 0 Oligopeptidase F ARL2_Bind_BART PF11527.8 CUU97418.1 - 0.15 12.2 2.5 0.21 11.7 0.6 2.0 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART SpecificRecomb PF10136.9 CUU97418.1 - 0.18 10.1 1.9 0.24 9.7 1.9 1.1 1 0 0 1 1 1 0 Site-specific recombinase MscS_porin PF12795.7 CUU97418.1 - 0.3 10.6 8.1 0.44 10.0 8.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain KELK PF15796.5 CUU97418.1 - 0.34 11.4 8.4 6.9 7.2 2.0 3.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec8_exocyst PF04048.14 CUU97418.1 - 0.34 10.8 2.6 1.2 9.1 0.4 2.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 CUU97418.1 - 0.43 10.6 4.9 1.3 9.0 4.9 1.9 1 0 0 1 1 1 0 Laminin Domain II DUF1640 PF07798.11 CUU97418.1 - 0.52 10.3 8.4 1.5 8.9 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) PRKG1_interact PF15898.5 CUU97418.1 - 0.75 10.7 8.7 9.8 7.1 7.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 CUU97418.1 - 0.81 9.0 4.7 1.9 7.8 4.5 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M TMPIT PF07851.13 CUU97418.1 - 1.3 8.2 4.7 2 7.6 4.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 CUU97418.1 - 1.8 9.2 9.8 0.53 10.9 1.8 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 CUU97418.1 - 2.8 7.8 11.6 2 8.3 0.4 3.4 2 1 1 3 3 3 0 Septum formation initiator Nucleotid_trans PF03407.16 CUU97421.1 - 0.14 12.2 0.3 0.23 11.4 0.1 1.4 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase MFS_1 PF07690.16 CUU97422.1 - 2e-08 33.6 13.4 2e-08 33.6 13.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 CUU97423.1 - 2.4e-39 135.4 6.1 2.4e-39 135.4 6.1 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 zf-C2H2_4 PF13894.6 CUU97424.1 - 0.048 14.5 13.2 6.5 7.9 0.3 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger POT1 PF02765.17 CUU97424.1 - 0.049 13.5 0.0 0.067 13.0 0.0 1.3 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 zf-ANAPC11 PF12861.7 CUU97424.1 - 0.27 11.3 5.1 0.12 12.4 3.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.26 CUU97424.1 - 2.9 8.5 14.3 1.7 9.3 0.2 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type RXLR PF16810.5 CUU97427.1 - 0.19 12.2 3.5 0.32 11.4 3.5 1.6 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity PWWP PF00855.17 CUU97428.1 - 3.1e-09 37.1 0.1 1.1e-08 35.3 0.1 2.0 2 0 0 2 2 2 1 PWWP domain Homeodomain PF00046.29 CUU97430.1 - 4.4e-08 32.8 0.1 4.4e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Homeodomain Tetraspanin PF00335.20 CUU97433.1 - 0.0077 16.0 0.8 0.012 15.3 0.8 1.2 1 0 0 1 1 1 1 Tetraspanin family PI-PLC-X PF00388.19 CUU97434.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ank_2 PF12796.7 CUU97435.1 - 3.3e-06 27.6 1.2 7.9e-05 23.2 0.4 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU97435.1 - 0.0041 17.7 0.1 0.97 10.1 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU97435.1 - 0.03 14.8 0.3 0.78 10.5 0.1 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 CUU97435.1 - 0.063 13.7 0.8 9.7 6.8 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeat SKIP_SNW PF02731.15 CUU97437.1 - 7.8e-67 223.9 2.1 7.8e-67 223.9 2.1 2.8 3 0 0 3 3 3 1 SKIP/SNW domain MRP-S31 PF15433.6 CUU97438.1 - 3.2e-47 161.7 5.0 4.1e-47 161.4 5.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Kazal_2 PF07648.15 CUU97441.1 - 7.9e-56 186.0 83.6 9.3e-11 41.7 2.7 9.1 8 0 0 8 8 8 7 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CUU97441.1 - 2.4e-30 104.3 88.4 2.4e-08 33.9 2.4 9.1 9 0 0 9 9 9 7 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.24 CUU97441.1 - 2.3e-28 99.3 0.0 1.9e-14 54.3 0.0 3.5 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.23 CUU97441.1 - 6.3e-24 84.7 0.0 1.5e-13 51.1 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_EGF PF00053.24 CUU97441.1 - 7.6e-13 48.4 34.1 6.1e-08 32.7 13.3 8.7 9 1 0 9 9 9 2 Laminin EGF domain Laminin_G_3 PF13385.6 CUU97441.1 - 0.0092 16.1 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Actin PF00022.19 CUU97442.1 - 3.9e-151 503.3 0.0 1.3e-150 501.6 0.0 1.6 1 1 0 1 1 1 1 Actin Ion_trans PF00520.31 CUU97444.1 - 7.6e-09 35.1 1.1 1.1e-08 34.7 1.1 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CUU97444.1 - 6.8e-08 32.5 0.1 1.1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NAM-associated PF14303.6 CUU97445.1 - 0.025 15.3 6.3 0.033 14.9 6.3 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ParA PF10609.9 CUU97446.1 - 1.5e-74 250.5 0.0 1.8e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CUU97446.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CUU97446.1 - 3e-05 23.4 0.2 5.5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_26 PF13500.6 CUU97446.1 - 0.00051 19.9 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_31 PF13614.6 CUU97446.1 - 0.0023 17.9 0.0 0.065 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CUU97446.1 - 0.022 14.0 0.0 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ CBP_BcsQ PF06564.12 CUU97446.1 - 0.027 13.9 0.1 0.053 13.0 0.1 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 CUU97446.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 CUU97446.1 - 0.084 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain BAR PF03114.18 CUU97447.1 - 5.2e-28 98.3 5.9 6.3e-28 98.0 5.9 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CUU97447.1 - 5.1e-09 35.7 5.1 7.5e-09 35.1 5.0 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4015 PF13200.6 CUU97447.1 - 0.0018 17.4 0.2 0.0024 17.0 0.2 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain LOH1CR12 PF10158.9 CUU97447.1 - 0.02 14.9 0.6 0.045 13.8 0.1 1.8 2 0 0 2 2 2 0 Tumour suppressor protein DUF4907 PF16250.5 CUU97447.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4907) Nipped-B_C PF12830.7 CUU97448.1 - 6.3e-60 202.4 0.2 1.2e-57 195.0 0.0 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CUU97448.1 - 4.3e-07 30.1 1.9 4.3e-07 30.1 1.9 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 CUU97448.1 - 1.3e-05 25.5 0.2 0.16 12.4 0.3 4.7 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CUU97448.1 - 0.00012 22.0 9.3 1.1 9.7 0.2 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 CUU97448.1 - 0.00013 22.4 0.0 30 5.3 0.0 5.3 4 0 0 4 4 4 0 HEAT-like repeat Cnd3 PF12719.7 CUU97448.1 - 0.0019 17.4 0.7 0.18 11.0 0.0 3.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CUU97448.1 - 0.013 15.5 10.6 0.042 13.9 0.7 4.9 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CUU97448.1 - 0.087 13.0 0.0 13 6.0 0.0 3.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase_Tyr PF07714.17 CUU97449.1 - 4.2e-84 281.9 0.0 5.7e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU97449.1 - 1e-40 139.8 0.0 1.6e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Focal_AT PF03623.13 CUU97449.1 - 2e-12 47.2 0.4 3.5e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Focal adhesion targeting region Haspin_kinase PF12330.8 CUU97449.1 - 0.014 14.4 0.2 0.047 12.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CUU97449.1 - 0.12 11.7 0.2 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like LLGL PF08366.13 CUU97451.1 - 1.2e-18 67.3 0.0 5.8e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 LLGL2 DSPc PF00782.20 CUU97454.1 - 7.6e-36 122.9 0.0 6.8e-22 77.7 0.0 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CUU97454.1 - 2.7e-17 63.2 0.0 1.5e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain DUF2892 PF11127.8 CUU97454.1 - 0.0063 16.5 2.4 3.2 7.9 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2892) Y_phosphatase PF00102.27 CUU97454.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_C48 PF02902.19 CUU97455.1 - 1.9e-34 119.4 0.6 3.2e-34 118.7 0.6 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tetraspanin PF00335.20 CUU97456.1 - 0.0098 15.6 1.5 0.012 15.3 1.5 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4029 PF13221.6 CUU97456.1 - 0.17 12.5 2.9 0.26 12.0 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) Guanylate_kin PF00625.21 CUU97457.1 - 4.1e-55 186.3 0.2 4.9e-55 186.0 0.2 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.6 CUU97457.1 - 0.00015 22.0 0.1 0.0003 21.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CUU97457.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CUU97457.1 - 0.002 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 CUU97457.1 - 0.0054 17.3 0.1 0.0088 16.6 0.1 1.7 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CUU97457.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CUU97457.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CUU97457.1 - 0.01 16.4 0.3 0.046 14.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 CUU97457.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CUU97457.1 - 0.019 15.1 0.1 0.043 13.9 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 CUU97457.1 - 0.021 14.6 0.4 0.7 9.6 0.0 2.3 3 0 0 3 3 2 0 Cytidylate kinase AAA_25 PF13481.6 CUU97457.1 - 0.025 14.2 0.1 0.056 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CUU97457.1 - 0.026 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Roc PF08477.13 CUU97457.1 - 0.038 14.2 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CUU97457.1 - 0.042 13.5 0.0 0.046 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CUU97457.1 - 0.048 13.4 0.1 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 CUU97457.1 - 0.051 14.1 1.2 0.1 13.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 CUU97457.1 - 0.059 12.8 0.1 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CUU97457.1 - 0.062 13.7 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 CUU97457.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain cobW PF02492.19 CUU97457.1 - 0.098 12.2 0.1 0.45 10.1 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CUU97457.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_4 PF13637.6 CUU97458.1 - 2.3e-25 88.6 2.9 4.9e-10 39.7 0.4 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CUU97458.1 - 4.7e-22 78.4 3.6 3e-14 53.3 0.7 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CUU97458.1 - 8.4e-20 70.6 3.1 1.3e-09 38.2 0.2 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU97458.1 - 8.2e-17 59.6 6.0 0.0002 21.5 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CUU97458.1 - 8.3e-17 60.8 10.5 1e-05 25.7 0.1 5.2 6 0 0 6 6 6 4 Ankyrin repeat FUSC PF04632.12 CUU97459.1 - 0.25 9.8 0.6 0.32 9.5 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tetraspanin PF00335.20 CUU97460.1 - 0.00014 21.6 6.8 0.00016 21.4 6.8 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0220 PF05255.11 CUU97460.1 - 0.059 12.9 8.3 1.3 8.5 1.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) Tetraspanin PF00335.20 CUU97461.1 - 2.2e-18 66.8 15.8 2.6e-18 66.6 15.8 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 CUU97461.1 - 0.052 13.6 16.8 0.85 9.7 14.7 2.7 1 1 1 2 2 2 0 CD20-like family Renin_r PF07850.14 CUU97461.1 - 0.23 12.1 0.4 1.1 9.9 0.0 2.2 1 1 0 2 2 2 0 Renin receptor-like protein Sld5 PF05916.11 CUU97462.1 - 0.00056 20.3 0.0 0.0008 19.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Spore_III_AB PF09548.10 CUU97462.1 - 0.042 14.0 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) KIAA1328 PF15369.6 CUU97463.1 - 1.6 8.5 9.2 2.1 8.1 3.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 UEV PF05743.13 CUU97464.1 - 2.7e-35 120.9 0.1 5.9e-35 119.8 0.1 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CUU97464.1 - 3.2e-23 81.4 0.0 9.8e-23 79.9 0.0 1.8 1 0 0 1 1 1 1 Vps23 core domain HAUS-augmin3 PF14932.6 CUU97464.1 - 0.00038 20.1 3.8 0.00061 19.5 3.8 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 UQ_con PF00179.26 CUU97464.1 - 0.005 16.5 0.1 0.015 15.0 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF745 PF05335.13 CUU97464.1 - 0.0087 15.8 1.4 0.017 14.9 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) PIN_8 PF18476.1 CUU97464.1 - 0.039 13.8 1.7 0.28 11.0 0.5 2.1 2 0 0 2 2 2 0 PIN like domain Poly_export PF02563.16 CUU97464.1 - 0.077 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein DUF4407 PF14362.6 CUU97464.1 - 0.085 12.2 3.0 0.22 10.8 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CUU97464.1 - 0.089 13.3 7.1 0.23 12.0 7.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CUU97464.1 - 0.11 10.4 1.1 0.14 10.1 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CUU97464.1 - 0.13 11.2 4.2 0.2 10.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS6_N PF14661.6 CUU97464.1 - 0.15 11.7 1.5 0.26 10.8 1.5 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Jnk-SapK_ap_N PF09744.9 CUU97464.1 - 0.17 12.1 9.2 0.04 14.1 5.8 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 CUU97464.1 - 0.22 11.9 1.7 0.58 10.5 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Dict-STAT-coil PF09267.10 CUU97464.1 - 0.22 11.9 1.8 0.46 10.9 1.3 1.7 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil Mod_r PF07200.13 CUU97464.1 - 0.29 11.2 10.4 0.15 12.1 6.6 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.11 CUU97464.1 - 0.5 10.5 3.1 1.1 9.4 3.1 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tup_N PF08581.10 CUU97464.1 - 1 9.7 5.0 0.63 10.4 2.5 1.9 2 0 0 2 2 2 0 Tup N-terminal RRM_1 PF00076.22 CUU97465.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 CUU97466.1 - 2.3e-47 158.7 11.0 6.1e-15 54.9 0.4 3.5 3 0 0 3 3 3 3 Helix-loop-helix DNA-binding domain Band_7_C PF16200.5 CUU97466.1 - 7.9e-05 22.6 0.1 13 5.9 0.0 3.9 5 0 0 5 5 5 0 C-terminal region of band_7 Phage_int_SAM_3 PF14659.6 CUU97466.1 - 0.00019 21.6 0.2 15 6.0 0.0 3.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF4665 PF15679.5 CUU97466.1 - 0.00056 20.5 1.3 12 6.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) TPR_21 PF09976.9 CUU97466.1 - 0.012 15.4 0.5 34 4.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ARS2 PF04959.13 CUU97466.1 - 0.023 15.1 0.3 61 3.9 0.0 3.4 3 0 0 3 3 3 0 Arsenite-resistance protein 2 Sec15 PF04091.12 CUU97466.1 - 0.025 14.0 2.4 16 4.8 0.0 3.4 3 0 0 3 3 3 0 Exocyst complex subunit Sec15-like NPF PF16601.5 CUU97466.1 - 0.029 14.8 6.6 22 5.5 0.2 3.4 3 0 0 3 3 3 0 Rabosyn-5 repeating NPF sequence-motif PROL5-SMR PF15621.6 CUU97466.1 - 0.038 14.5 2.9 11 6.6 0.1 3.0 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family DUF4525 PF15027.6 CUU97466.1 - 0.047 13.4 0.0 70 3.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4525) RNA_pol_L_2 PF13656.6 CUU97466.1 - 0.058 13.2 0.8 16 5.3 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain PMBR PF09373.10 CUU97466.1 - 0.075 13.2 0.1 1.4e+02 2.9 0.0 3.7 3 0 0 3 3 3 0 Pseudomurein-binding repeat CCDC106 PF15794.5 CUU97466.1 - 0.13 12.0 3.8 9.3 5.9 0.1 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 SRP54_N PF02881.19 CUU97466.1 - 0.17 12.1 0.2 1.7e+02 2.5 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Gly_radical PF01228.21 CUU97466.1 - 0.18 12.4 0.0 52 4.4 0.0 2.8 3 0 0 3 3 3 0 Glycine radical TPR_18 PF13512.6 CUU97466.1 - 0.65 10.1 2.8 1e+02 3.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RVT_1 PF00078.27 CUU97467.1 - 2.5e-20 73.0 0.0 3.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 CUU97468.1 - 3.3e-26 92.1 0.0 2.3e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 Cytochrome P450 zf-C4 PF00105.18 CUU97468.1 - 1.3e-23 83.2 12.7 2.5e-23 82.3 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CUU97468.1 - 1.2e-18 67.4 0.1 1.2e-18 67.4 0.1 1.8 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor RNase_P_p30 PF01876.16 CUU97472.1 - 5.4e-26 91.4 0.0 6.7e-25 87.8 0.0 2.1 1 1 0 1 1 1 1 RNase P subunit p30 DUF4704 PF15787.5 CUU97473.1 - 4e-10 39.4 0.0 4.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Macoilin PF09726.9 CUU97474.1 - 6.3e-31 107.7 51.8 9.9e-28 97.1 28.3 2.6 1 1 2 3 3 3 2 Macoilin family ATG16 PF08614.11 CUU97474.1 - 2e-07 31.5 39.7 5.8e-05 23.4 1.8 3.4 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 CUU97474.1 - 0.0069 16.7 4.7 0.0069 16.7 4.7 4.4 3 1 1 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin_3 PF13758.6 CUU97474.1 - 0.15 12.1 7.7 0.076 13.1 2.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit DUF812 PF05667.11 CUU97474.1 - 0.46 9.3 25.7 0.5 9.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) FPP PF05911.11 CUU97474.1 - 1.4 7.0 38.9 0.015 13.5 3.8 2.9 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 CUU97474.1 - 4.3 6.7 29.9 2.1 7.8 13.1 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 Rootletin PF15035.6 CUU97474.1 - 5 7.1 29.8 0.74 9.8 7.7 2.7 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion LIM PF00412.22 CUU97475.1 - 9.3e-22 77.0 13.9 4.4e-12 46.0 0.6 4.1 4 0 0 4 4 4 3 LIM domain DZR PF12773.7 CUU97475.1 - 0.00031 20.7 15.2 0.42 10.7 4.1 3.6 1 1 2 3 3 3 2 Double zinc ribbon zf-RING_7 PF02591.15 CUU97475.1 - 0.034 14.3 10.9 0.98 9.7 6.5 3.3 2 1 0 2 2 2 0 C4-type zinc ribbon domain zf-C3HC4_3 PF13920.6 CUU97475.1 - 5.9 6.8 26.5 2.4 8.1 7.4 4.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) LIM PF00412.22 CUU97476.1 - 7.1e-21 74.2 14.1 8.1e-12 45.2 0.6 4.1 4 0 0 4 4 4 3 LIM domain DZR PF12773.7 CUU97476.1 - 0.0011 18.9 14.6 0.57 10.3 3.6 3.5 1 1 2 3 3 3 2 Double zinc ribbon zf-RING_7 PF02591.15 CUU97476.1 - 0.091 13.0 10.4 1.2 9.3 6.1 3.1 2 1 0 2 2 2 0 C4-type zinc ribbon domain c-SKI_SMAD_bind PF08782.10 CUU97476.1 - 7.1 6.9 6.2 19 5.5 0.5 2.6 2 0 0 2 2 2 0 c-SKI Smad4 binding domain NumbF PF06311.12 CUU97478.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.5 1 0 0 1 1 1 0 NUMB domain DAG1 PF05454.11 CUU97479.1 - 3.3e-05 23.4 0.8 0.09 12.1 0.0 2.3 2 0 0 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) SpoIIIAH PF12685.7 CUU97479.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Kei1 PF08552.11 CUU97479.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMEM154 PF15102.6 CUU97479.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF4834 PF16118.5 CUU97479.1 - 0.15 13.0 0.0 0.29 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FPP PF05911.11 CUU97481.1 - 0.0065 14.7 0.1 0.0068 14.7 0.1 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 CUU97481.1 - 0.008 16.2 3.7 0.01 15.9 3.7 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain HOOK PF05622.12 CUU97481.1 - 0.011 13.9 0.2 0.012 13.8 0.2 1.0 1 0 0 1 1 1 0 HOOK protein Cep57_CLD_2 PF14197.6 CUU97481.1 - 0.16 12.0 8.5 0.43 10.7 8.6 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 HTH_48 PF17906.1 CUU97482.1 - 7e-05 22.9 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase Pkinase PF00069.25 CUU97484.1 - 0.027 13.9 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Homeobox_KN PF05920.11 CUU97485.1 - 9.3e-06 25.4 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF1852 PF08908.11 CUU97485.1 - 0.0033 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) Acylphosphatase PF00708.18 CUU97488.1 - 2.1e-21 76.1 0.1 2.4e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase PNKP-ligase_C PF16536.5 CUU97488.1 - 0.032 14.5 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Cas1_AcylT PF07779.12 CUU97489.1 - 6e-18 65.0 4.2 6.6e-18 64.9 4.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p pEK499_p136 PF18736.1 CUU97490.1 - 0.046 13.3 0.2 0.066 12.8 0.2 1.4 1 1 0 1 1 1 0 HEPN pEK499 p136 F-box-like PF12937.7 CUU97491.1 - 1.8e-08 34.1 2.7 6e-08 32.5 2.7 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CUU97491.1 - 2.1e-06 27.5 2.3 6.4e-06 25.9 2.3 1.9 1 0 0 1 1 1 1 F-box domain Homeodomain PF00046.29 CUU97494.1 - 1.9e-20 72.4 3.9 2.9e-20 71.8 3.9 1.3 1 0 0 1 1 1 1 Homeodomain HTH_28 PF13518.6 CUU97494.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Homeobox_KN PF05920.11 CUU97494.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 CUU97494.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CUU97494.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_Mga PF08280.11 CUU97494.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Nop14 PF04147.12 CUU97498.1 - 0.00012 20.5 19.8 0.00013 20.4 19.8 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CUU97498.1 - 0.00019 21.0 18.5 0.00019 21.0 18.5 1.1 1 0 0 1 1 1 1 SDA1 Tim54 PF11711.8 CUU97498.1 - 0.00099 18.0 3.9 0.0013 17.6 3.9 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ADP_ribosyl_GH PF03747.14 CUU97498.1 - 0.0017 18.1 0.3 0.0021 17.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PTPRCAP PF15713.5 CUU97498.1 - 0.0033 17.7 16.3 0.0044 17.3 16.3 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 CUU97498.1 - 0.0039 16.6 17.9 0.0044 16.4 17.9 1.1 1 0 0 1 1 1 1 BUD22 Connexin PF00029.19 CUU97498.1 - 0.0045 16.8 0.1 0.0057 16.4 0.1 1.2 1 0 0 1 1 1 1 Connexin RNA_pol_Rpc4 PF05132.14 CUU97498.1 - 0.019 15.4 4.7 0.025 15.0 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 CUU97498.1 - 0.021 14.3 5.3 0.023 14.1 5.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 CUU97498.1 - 0.021 14.6 7.4 0.023 14.5 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 CUU97498.1 - 0.022 13.3 23.3 0.026 13.0 23.3 1.0 1 0 0 1 1 1 0 Mpp10 protein CPSF100_C PF13299.6 CUU97498.1 - 0.023 14.9 2.8 0.031 14.5 2.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CUU97498.1 - 0.027 13.5 1.9 0.029 13.3 1.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 CUU97498.1 - 0.059 12.6 2.8 0.07 12.3 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_3_Rpc31 PF11705.8 CUU97498.1 - 0.11 12.8 26.9 0.16 12.2 26.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RP-C_C PF11800.8 CUU97498.1 - 0.11 12.5 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4820 PF16091.5 CUU97498.1 - 0.12 11.7 4.1 0.14 11.5 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RAP1 PF07218.11 CUU97498.1 - 0.13 10.5 8.6 0.17 10.1 8.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NARP1 PF12569.8 CUU97498.1 - 0.15 10.9 6.9 0.18 10.7 6.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAPS PF04499.15 CUU97498.1 - 0.16 10.7 7.6 0.18 10.5 7.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Merozoite_SPAM PF07133.11 CUU97498.1 - 0.17 11.9 35.8 0.21 11.6 35.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Vfa1 PF08432.10 CUU97498.1 - 0.22 11.8 12.4 0.36 11.2 12.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIIAH PF12685.7 CUU97498.1 - 0.34 10.7 11.4 0.41 10.4 11.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.13 CUU97498.1 - 0.35 9.6 7.3 0.4 9.4 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2201_N PF13203.6 CUU97498.1 - 0.41 10.2 3.1 0.48 10.0 3.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF5523 PF17661.1 CUU97498.1 - 0.66 9.6 20.5 0.88 9.2 20.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Presenilin PF01080.17 CUU97498.1 - 0.72 8.5 5.9 0.87 8.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin Drc1-Sld2 PF11719.8 CUU97498.1 - 0.76 9.3 12.6 0.88 9.0 12.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein V_ATPase_I PF01496.19 CUU97498.1 - 0.9 7.4 7.5 1.1 7.1 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 CUU97498.1 - 0.97 8.6 14.5 1.3 8.2 14.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CUU97498.1 - 0.99 7.6 22.6 1.2 7.3 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 CUU97498.1 - 1 9.3 19.9 1.1 9.2 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2151 PF10221.9 CUU97498.1 - 1.2 7.6 6.0 1.4 7.4 6.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator MAP17 PF15807.5 CUU97498.1 - 1.6 9.0 8.5 2.6 8.3 8.5 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MRNIP PF15749.5 CUU97498.1 - 2.5 8.9 7.8 4.5 8.0 7.8 1.5 1 0 0 1 1 1 0 MRN-interacting protein THOC2_N PF16134.5 CUU97498.1 - 3.1 6.3 5.9 3.9 6.0 5.9 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus PPL5 PF18168.1 CUU97498.1 - 3.5 6.8 7.7 4.2 6.6 7.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Paf1 PF03985.13 CUU97498.1 - 5.8 5.8 25.2 7.5 5.4 25.2 1.1 1 0 0 1 1 1 0 Paf1 COPI_C PF06957.11 CUU97498.1 - 6.2 5.5 15.2 7.7 5.2 15.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus EST1_DNA_bind PF10373.9 CUU97499.1 - 1.1e-26 94.0 6.5 1.1e-12 48.1 0.7 2.8 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 CUU97499.1 - 2.1e-15 57.5 2.7 4.2e-08 33.9 0.3 3.8 3 2 0 3 3 2 2 Telomerase activating protein Est1 Cas_Csy4 PF09618.10 CUU97499.1 - 4.4e-06 26.9 1.3 0.26 11.4 0.2 3.6 4 0 0 4 4 4 2 CRISPR-associated protein (Cas_Csy4) PSY3 PF16836.5 CUU97499.1 - 8.6e-06 25.4 0.7 0.16 11.4 0.1 2.7 2 0 0 2 2 2 2 Shu complex component Psy3, DNA-binding description TMF_TATA_bd PF12325.8 CUU97499.1 - 0.00065 19.9 0.9 2.1 8.6 0.1 2.9 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF5045 PF16464.5 CUU97499.1 - 0.0016 18.7 0.2 3.7 7.9 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF5045) DUF2301 PF10063.9 CUU97499.1 - 0.057 13.8 0.5 17 5.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) DUF1492 PF07374.11 CUU97499.1 - 0.064 13.4 0.3 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) DPM3 PF08285.11 CUU97499.1 - 0.1 12.8 0.9 23 5.2 0.1 2.7 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TPR_17 PF13431.6 CUU97499.1 - 0.13 12.6 0.0 49 4.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3509 PF12021.8 CUU97499.1 - 0.16 11.7 0.1 69 3.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3509) Tropomyosin PF00261.20 CUU97499.1 - 0.18 11.1 4.8 6.4 6.1 0.4 2.7 2 0 0 2 2 2 0 Tropomyosin TPR_11 PF13414.6 CUU97499.1 - 1.7 8.4 4.3 46 3.8 0.1 3.5 4 0 0 4 4 4 0 TPR repeat MAP17 PF15807.5 CUU97501.1 - 5.6 7.2 6.6 0.8 9.9 2.1 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF981 PF06168.11 CUU97505.1 - 0.048 13.6 6.2 0.036 14.0 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF981) ABC2_membrane_5 PF13346.6 CUU97505.1 - 0.24 10.9 13.0 0.31 10.6 13.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 CUU97506.1 - 1.2e-18 67.7 14.7 1.5e-18 67.4 14.7 1.1 1 0 0 1 1 1 1 Tetraspanin family VIT1 PF01988.19 CUU97506.1 - 0.00062 19.7 2.7 0.001 19.0 2.7 1.4 1 0 0 1 1 1 1 VIT family 5TM-5TMR_LYT PF07694.12 CUU97506.1 - 0.0039 16.7 4.6 0.025 14.1 1.1 2.3 2 0 0 2 2 2 1 5TMR of 5TMR-LYT DUF3377 PF11857.8 CUU97506.1 - 0.12 12.3 6.7 1.7 8.6 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Ninjurin PF04923.12 CUU97506.1 - 0.16 11.9 3.4 0.46 10.5 0.6 2.5 2 1 0 2 2 2 0 Ninjurin JSRP PF15312.6 CUU97506.1 - 0.43 10.5 2.0 24 4.9 0.8 2.4 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF4199 PF13858.6 CUU97506.1 - 0.8 10.1 7.7 1 9.7 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ABC2_membrane_3 PF12698.7 CUU97506.1 - 3.1 6.8 14.9 1 8.4 10.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein Ribosomal_L28 PF00830.19 CUU97508.1 - 0.028 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L28 family HARE-HTH PF05066.13 CUU97508.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Myotub-related PF06602.14 CUU97509.1 - 2.5e-86 289.8 0.1 3.9e-86 289.2 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CUU97509.1 - 0.0019 18.0 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4140 PF13600.6 CUU97509.1 - 0.0084 16.5 0.1 0.033 14.6 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Y_phosphatase3 PF13350.6 CUU97509.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family YlqD PF11068.8 CUU97509.1 - 0.06 13.7 1.0 0.13 12.6 1.0 1.6 1 0 0 1 1 1 0 YlqD protein Y_phosphatase PF00102.27 CUU97509.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4407 PF14362.6 CUU97509.1 - 0.22 10.9 0.7 0.36 10.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CUU97509.1 - 0.29 10.9 7.4 0.21 11.4 5.0 1.9 2 0 0 2 2 2 0 Septum formation initiator OCRE PF17780.1 CUU97510.1 - 9.4e-17 60.8 14.8 1.8e-16 59.8 14.8 1.5 1 0 0 1 1 1 1 OCRE domain G-patch PF01585.23 CUU97510.1 - 1.9e-13 50.1 1.7 4.3e-13 48.9 1.7 1.6 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 CUU97510.1 - 1.3e-11 44.6 0.1 1.3e-11 44.6 0.1 2.2 2 1 0 2 2 2 1 FHA domain G-patch_2 PF12656.7 CUU97510.1 - 4.2e-06 26.8 0.6 1.2e-05 25.3 0.6 1.8 1 0 0 1 1 1 1 G-patch domain Orai-1 PF07856.12 CUU97511.1 - 8.4e-58 194.9 8.0 1e-57 194.6 8.0 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF1129 PF06570.11 CUU97511.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF4083 PF13314.6 CUU97511.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF4579 PF15158.6 CUU97511.1 - 0.19 11.5 3.2 0.34 10.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) Phage_holin_3_6 PF07332.11 CUU97511.1 - 0.57 10.2 10.9 0.11 12.5 1.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III FtsX PF02687.21 CUU97511.1 - 2.6 8.6 12.0 0.22 12.0 5.8 2.3 1 1 1 2 2 2 0 FtsX-like permease family DUF4191 PF13829.6 CUU97511.1 - 2.7 7.3 5.0 0.62 9.4 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Orai-1 PF07856.12 CUU97512.1 - 6.5e-57 192.0 9.0 9.4e-57 191.5 9.0 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Pyr_redox_2 PF07992.14 CUU97512.1 - 3.8e-18 65.7 0.0 1e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 CUU97512.1 - 4.1e-05 23.4 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 CUU97512.1 - 0.0059 17.1 1.3 2.7 8.6 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CUU97512.1 - 0.015 14.4 0.9 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DUF2207 PF09972.9 CUU97512.1 - 0.017 13.9 1.3 0.028 13.2 1.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NAD_binding_9 PF13454.6 CUU97512.1 - 0.036 14.1 0.0 3.4 7.6 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CUU97512.1 - 0.085 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1129 PF06570.11 CUU97512.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) MICSWaP PF17018.5 CUU97513.1 - 0.001 18.7 5.9 0.0016 18.0 5.9 1.2 1 0 0 1 1 1 1 Spore wall protein zf-C2H2_9 PF16293.5 CUU97515.1 - 0.061 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) CAP_N PF01213.19 CUU97516.1 - 3.2 7.1 4.8 3.8 6.9 4.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-LITAF-like PF10601.9 CUU97517.1 - 8.2e-14 51.6 6.9 1.2e-13 51.1 6.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc-ribbons_6 PF07191.12 CUU97517.1 - 0.71 9.9 7.4 7 6.7 1.9 2.2 1 1 1 2 2 2 0 zinc-ribbons Cystatin PF00031.21 CUU97518.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Cystatin domain PilN PF05137.13 CUU97518.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 Fimbrial assembly protein (PilN) SQAPI PF16845.5 CUU97518.1 - 0.018 15.4 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor RNase_H PF00075.24 CUU97519.1 - 0.00016 21.8 0.1 0.00066 19.9 0.0 2.1 1 1 0 1 1 1 1 RNase H TssO PF17561.2 CUU97520.1 - 0.033 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF2135 PF09906.9 CUU97520.1 - 0.077 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) GCP_C_terminal PF04130.13 CUU97521.1 - 2e-71 241.0 1.1 2e-71 241.0 1.1 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CUU97521.1 - 3.3e-56 191.2 1.0 6.9e-56 190.1 1.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Forkhead PF00250.18 CUU97523.1 - 1.4e-38 131.0 0.4 2.2e-38 130.4 0.1 1.5 2 0 0 2 2 2 1 Forkhead domain Forkhead PF00250.18 CUU97524.1 - 1.4e-38 131.0 0.4 2.2e-38 130.4 0.1 1.5 2 0 0 2 2 2 1 Forkhead domain VSG_B PF13206.6 CUU97525.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain RRM_1 PF00076.22 CUU97530.1 - 4.3e-09 36.1 0.0 5.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRM1_repeat PF18777.1 CUU97530.1 - 0.0031 17.0 0.6 0.0068 15.9 0.6 1.7 1 1 0 1 1 1 1 Chromosome region maintenance or exportin repeat G-7-MTase PF12803.7 CUU97530.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Ion_trans_2 PF07885.16 CUU97532.1 - 4.1e-14 52.3 7.5 8.7e-14 51.2 7.5 1.6 1 1 0 1 1 1 1 Ion channel Sensor PF13796.6 CUU97532.1 - 0.0048 16.9 1.6 1.7 8.7 0.5 2.1 2 0 0 2 2 2 2 Putative sensor DUF2070 PF09843.9 CUU97532.1 - 0.1 10.9 4.1 0.14 10.4 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2304 PF10066.9 CUU97532.1 - 0.14 12.4 3.5 2.4 8.4 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF1180 PF06679.12 CUU97532.1 - 3.5 8.0 5.0 1.7 9.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) ASC PF00858.24 CUU97534.1 - 1.2e-11 44.3 0.8 1.9e-11 43.6 0.8 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4131 PF13567.6 CUU97534.1 - 0.00095 18.8 0.3 0.0016 18.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) PDR_assoc PF08370.11 CUU97534.1 - 0.061 13.1 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Plant PDR ABC transporter associated RT_RNaseH PF17917.1 CUU97536.1 - 6.8e-24 84.2 0.1 8.2e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CUU97536.1 - 8.2e-20 70.7 0.1 1.3e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CUU97537.1 - 1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sina PF03145.16 CUU97537.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Seven in absentia protein family bZIP_1 PF00170.21 CUU97539.1 - 5.4e-15 55.2 12.2 1.1e-14 54.3 12.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CUU97539.1 - 1.2e-06 28.5 14.4 1.2e-06 28.5 14.4 1.9 2 0 0 2 2 2 1 Basic region leucine zipper ASD2 PF08687.11 CUU97539.1 - 6.3e-05 22.7 0.9 6.3e-05 22.7 0.9 1.5 2 0 0 2 2 2 1 Apx/Shroom domain ASD2 bZIP_Maf PF03131.17 CUU97539.1 - 0.023 15.2 9.3 0.023 15.2 9.3 3.1 4 0 0 4 4 4 0 bZIP Maf transcription factor Tetraspanin PF00335.20 CUU97540.1 - 4e-26 92.1 5.0 4.9e-26 91.9 5.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Chlam_OMP3 PF03503.13 CUU97540.1 - 0.028 14.7 2.2 0.057 13.7 2.2 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 TMEM154 PF15102.6 CUU97540.1 - 1 9.3 0.0 1 9.3 0.0 2.2 2 1 0 2 2 2 0 TMEM154 protein family KH_1 PF00013.29 CUU97541.1 - 2.8e-17 62.3 2.1 0.0023 17.7 0.1 6.3 4 2 0 4 4 4 4 KH domain KH_9 PF17904.1 CUU97541.1 - 3.8e-14 52.8 0.0 1.8e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 FMRP KH0 domain Agenet PF05641.12 CUU97541.1 - 6.3e-05 23.4 0.0 0.84 10.1 0.0 2.8 2 0 0 2 2 2 2 Agenet domain KH_2 PF07650.17 CUU97541.1 - 0.0057 16.4 1.2 70 3.4 0.0 4.4 4 0 0 4 4 4 0 KH domain T3SS_needle_E PF08988.10 CUU97541.1 - 0.11 12.7 0.7 47 4.2 0.0 3.7 4 0 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle DGF-1_5 PF11038.8 CUU97541.1 - 0.22 10.8 1.3 15 4.8 0.1 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DUF2799 PF10973.8 CUU97541.1 - 3.9 8.0 8.9 2.4e+02 2.2 0.1 5.0 6 0 0 6 6 6 0 Protein of unknown function (DUF2799) UAA PF08449.11 CUU97544.1 - 1.7e-60 204.8 17.4 2.1e-60 204.5 17.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CUU97544.1 - 0.0004 20.6 24.4 0.022 14.9 11.0 2.9 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CUU97544.1 - 0.001 18.5 7.6 0.0038 16.6 7.3 2.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family Ion_trans PF00520.31 CUU97546.1 - 9.2e-31 106.9 19.5 4e-25 88.5 12.5 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CUU97546.1 - 8.4e-13 47.8 13.5 2.1e-09 36.6 10.3 2.1 2 0 0 2 2 2 2 Polycystin cation channel DUF4088 PF13317.6 CUU97546.1 - 6.6e-05 22.6 0.1 0.61 9.6 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF4088) TMEM82 PF15816.5 CUU97546.1 - 0.034 13.1 0.1 8.2 5.3 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 82 rve_3 PF13683.6 CUU97549.1 - 0.055 13.3 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Integrase core domain Spore-coat_CotZ PF10612.9 CUU97550.1 - 0.045 13.9 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Spore coat protein Z DUF4394 PF14339.6 CUU97551.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF4446 PF14584.6 CUU97552.1 - 0.073 13.0 0.1 0.1 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4446 PF14584.6 CUU97553.1 - 0.073 13.0 0.1 0.1 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) PH PF00169.29 CUU97554.1 - 3.2e-07 30.8 0.0 1e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_12 PF16457.5 CUU97554.1 - 1.2e-05 25.8 0.0 0.00017 22.1 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain CAS_C PF12026.8 CUU97554.1 - 1.3 9.0 8.9 0.2 11.7 0.5 2.9 3 0 0 3 3 3 0 Crk-Associated Substrate C-terminal domain DUF1043 PF06295.12 CUU97554.1 - 2 8.4 7.9 4.7 7.2 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tup_N PF08581.10 CUU97554.1 - 2.4 8.5 14.9 0.42 11.0 10.9 1.8 2 0 0 2 2 2 0 Tup N-terminal Arrestin_C PF02752.22 CUU97555.1 - 7e-25 88.0 0.1 1.5e-24 86.9 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CUU97555.1 - 1.6e-07 31.5 0.4 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MFS_1 PF07690.16 CUU97556.1 - 4.5e-28 98.2 15.5 4.5e-28 98.2 15.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CUU97556.1 - 2.8e-06 26.5 1.8 2.8e-06 26.5 1.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 CUU97556.1 - 0.0014 17.1 12.5 0.034 12.5 2.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Spectrin PF00435.21 CUU97557.1 - 0.078 13.5 2.4 0.2 12.1 2.4 1.7 1 1 0 1 1 1 0 Spectrin repeat MOSC_N PF03476.16 CUU97557.1 - 0.13 12.1 0.1 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain FapA PF03961.13 CUU97557.1 - 0.49 8.9 5.1 0.84 8.2 5.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cgr1 PF03879.14 CUU97557.1 - 5.7 7.4 7.5 1.9 8.9 4.2 2.0 2 0 0 2 2 2 0 Cgr1 family ATG16 PF08614.11 CUU97557.1 - 7.3 6.8 11.7 4.9 7.3 5.3 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) RRM_1 PF00076.22 CUU97558.1 - 5.7e-07 29.3 0.3 0.00022 21.0 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CUU97558.1 - 0.0019 18.2 0.0 0.0065 16.4 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.6 CUU97558.1 - 0.016 14.8 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) RRM_3 PF08777.11 CUU97558.1 - 0.043 13.9 0.2 0.98 9.5 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif Calcipressin PF04847.12 CUU97558.1 - 0.058 13.1 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Calcipressin Rhodanese PF00581.20 CUU97560.1 - 7.3e-10 39.3 0.0 3.9e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain TBCC PF07986.12 CUU97561.1 - 6.5e-33 113.0 2.0 6.5e-33 113.0 2.0 1.4 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 CUU97561.1 - 0.061 12.9 0.4 0.096 12.3 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal PIH1_CS PF18201.1 CUU97562.1 - 4.6e-13 49.4 0.1 7.4e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 CUU97562.1 - 0.0016 19.4 0.2 0.0041 18.1 0.2 1.7 1 0 0 1 1 1 1 CS domain ArsA_HSP20 PF17886.1 CUU97562.1 - 0.0028 17.2 0.1 0.0042 16.6 0.1 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Tetraspanin PF00335.20 CUU97564.1 - 1.5e-42 145.8 12.5 1.8e-42 145.6 12.5 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF3040 PF11239.8 CUU97564.1 - 5.7 7.3 10.4 2.6 8.4 5.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Snf7 PF03357.21 CUU97565.1 - 6.5e-30 104.0 18.3 9.2e-30 103.5 18.3 1.3 1 0 0 1 1 1 1 Snf7 YusW PF14039.6 CUU97565.1 - 0.047 14.2 1.2 0.047 14.2 1.2 2.1 2 0 0 2 2 2 0 YusW-like protein DnaJ-X PF14308.6 CUU97565.1 - 1 8.7 14.2 0.011 15.2 6.3 1.6 2 0 0 2 2 2 0 X-domain of DnaJ-containing SirA PF10747.9 CUU97565.1 - 2.8 8.3 6.2 1 9.7 0.7 2.1 1 1 0 2 2 2 0 Sporulation inhibitor of replication protein SirA Josephin PF02099.17 CUU97566.1 - 2e-35 122.3 0.0 4.5e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Josephin UIM PF02809.20 CUU97566.1 - 0.024 14.5 13.9 0.13 12.2 2.8 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif Radial_spoke PF04712.12 CUU97567.1 - 0.03 13.3 0.0 0.12 11.3 0.0 1.9 2 1 0 2 2 2 0 Radial spokehead-like protein FYVE_2 PF02318.16 CUU97567.1 - 0.25 11.6 0.3 0.37 11.0 0.3 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger CMS1 PF14617.6 CUU97570.1 - 0.017 14.5 0.7 0.017 14.5 0.7 1.7 1 1 1 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Phage_T4_gp19 PF06841.12 CUU97570.1 - 0.025 14.4 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 Nop25 PF09805.9 CUU97570.1 - 2.3 8.7 18.3 8.6 6.8 18.3 2.0 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) ETC_C1_NDUFA5 PF04716.14 CUU97571.1 - 2.3e-25 88.2 0.3 3.3e-25 87.7 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region NEL PF14496.6 CUU97571.1 - 0.03 13.8 0.2 0.22 10.9 0.1 1.9 1 1 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting Pep3_Vps18 PF05131.14 CUU97575.1 - 4.7e-27 94.6 0.0 1.9e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CUU97575.1 - 2.9e-06 27.2 1.6 0.077 12.9 0.1 3.9 4 0 0 4 4 4 2 Region in Clathrin and VPS AA_permease_2 PF13520.6 CUU97576.1 - 1.1e-28 100.3 18.3 1.2e-28 100.1 18.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CUU97576.1 - 8.8e-13 47.7 16.5 1.1e-12 47.4 16.5 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CUU97576.1 - 8.4e-06 25.1 13.2 1e-05 24.7 13.2 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family UBA_3 PF09288.10 CUU97576.1 - 0.14 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain TMEM132D_C PF15706.5 CUU97576.1 - 2.6 7.9 4.3 16 5.3 0.7 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pep3_Vps18 PF05131.14 CUU97577.1 - 5.6e-27 94.4 0.0 2.1e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CUU97577.1 - 3.3e-06 27.0 1.6 0.084 12.7 0.1 4.0 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CUU97577.1 - 7.9e-06 26.3 0.2 2.5e-05 24.7 0.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 CUU97577.1 - 7.4e-05 23.0 0.8 0.0003 21.0 0.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CUU97577.1 - 0.00025 20.7 4.1 0.00076 19.2 4.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CUU97577.1 - 0.00029 20.6 1.3 0.00087 19.1 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CUU97577.1 - 0.00038 20.4 0.3 0.00038 20.4 0.3 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CUU97577.1 - 0.00056 19.9 0.7 0.0017 18.3 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CUU97577.1 - 0.0084 16.0 0.9 0.029 14.2 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CUU97577.1 - 0.015 14.9 0.5 0.043 13.4 0.5 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CUU97577.1 - 0.44 10.5 3.5 0.51 10.2 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HTH_48 PF17906.1 CUU97578.1 - 0.00021 21.3 0.5 0.93 9.7 0.1 2.5 2 0 0 2 2 2 2 HTH domain in Mos1 transposase DUF1935 PF09149.10 CUU97578.1 - 0.00055 20.3 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) SH3_4 PF06347.13 CUU97578.1 - 0.028 14.2 0.1 15 5.5 0.0 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain DUF1883 PF08980.10 CUU97578.1 - 0.12 12.4 0.4 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) LIN37 PF15306.6 CUU97578.1 - 0.14 12.4 2.9 11 6.2 0.2 2.2 2 0 0 2 2 2 0 LIN37 ATPgrasp_TupA PF14305.6 CUU97578.1 - 0.16 11.8 0.1 21 4.8 0.0 2.1 2 0 0 2 2 2 0 TupA-like ATPgrasp Tmp39 PF10271.9 CUU97579.1 - 4.6e-50 170.9 6.1 5.2e-50 170.7 6.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Aminotran_1_2 PF00155.21 CUU97580.1 - 2.3e-55 188.2 0.0 3e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 CUU97580.1 - 7.5e-14 51.9 7.0 0.0064 17.3 0.1 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CUU97580.1 - 9e-13 48.3 0.0 5.9e-12 45.7 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex PI3K_1B_p101 PF10486.9 CUU97580.1 - 0.0021 15.9 0.6 0.0021 15.9 0.6 1.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Aminotran_5 PF00266.19 CUU97580.1 - 0.004 16.2 0.0 0.0088 15.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V PNP_phzG_C PF10590.9 CUU97581.1 - 7.6e-17 61.1 0.7 1.8e-16 60.0 0.7 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CUU97581.1 - 3.3e-08 33.6 0.1 2.9e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase KdpC PF02669.15 CUU97581.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Pyridox_oxase_2 PF12766.7 CUU97581.1 - 0.075 13.7 0.0 3.5 8.3 0.0 2.4 1 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase MMM1 PF10296.9 CUU97582.1 - 0.011 14.9 1.5 0.2 10.7 0.1 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 VPS28 PF03997.12 CUU97583.1 - 2.3e-48 164.4 0.1 3.5e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 VPS28 protein Smg4_UPF3 PF03467.15 CUU97586.1 - 6.3e-42 143.5 8.4 8.3e-32 110.6 1.6 2.6 2 0 0 2 2 2 2 Smg-4/UPF3 family Fels1 PF05666.11 CUU97586.1 - 0.015 14.9 0.0 10 5.9 0.0 2.8 3 0 0 3 3 3 0 Fels-1 Prophage Protein-like RRM_1 PF00076.22 CUU97586.1 - 0.023 14.5 0.1 0.023 14.5 0.1 2.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF29 PF01724.16 CUU97586.1 - 0.18 12.0 3.5 11 6.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF29 RRM_3 PF08777.11 CUU97586.1 - 0.83 9.7 5.4 0.48 10.5 0.6 2.9 2 2 0 2 2 2 0 RNA binding motif Remorin_C PF03763.13 CUU97586.1 - 6 6.8 13.8 11 6.0 3.1 2.4 2 0 0 2 2 2 0 Remorin, C-terminal region CDC24_OB1 PF17246.2 CUU97586.1 - 9.2 6.4 7.6 30 4.8 0.9 2.5 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 RRN3 PF05327.11 CUU97587.1 - 1 7.9 5.3 1.1 7.7 5.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 CUU97587.1 - 1.2 8.7 4.6 1.2 8.7 4.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cnd2 PF05786.14 CUU97587.1 - 2.3 6.8 8.1 2.2 6.8 8.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2457 PF10446.9 CUU97587.1 - 3.9 6.5 11.5 4.2 6.4 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Osteopontin PF00865.18 CUU97587.1 - 4.2 6.8 14.5 5 6.5 14.5 1.0 1 0 0 1 1 1 0 Osteopontin Pes-10 PF07149.11 CUU97587.1 - 5.1 6.0 6.4 5.9 5.8 6.4 1.1 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 CUU97587.1 - 9.5 4.2 11.2 9.3 4.2 11.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 CUU97588.1 - 0.1 12.2 2.9 0.11 12.1 2.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 CUU97588.1 - 0.62 8.5 3.3 0.69 8.4 3.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 CUU97588.1 - 1.3 8.0 5.2 1.5 7.8 5.2 1.1 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 CUU97588.1 - 3.9 5.5 12.1 4.4 5.3 12.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 CUU97588.1 - 6.6 5.8 11.5 7.3 5.6 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 CUU97589.1 - 1 7.9 5.3 1.1 7.7 5.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 CUU97589.1 - 1.2 8.7 4.6 1.2 8.7 4.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cnd2 PF05786.14 CUU97589.1 - 2.3 6.8 8.1 2.2 6.8 8.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF2457 PF10446.9 CUU97589.1 - 3.9 6.5 11.5 4.2 6.4 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Osteopontin PF00865.18 CUU97589.1 - 4.2 6.8 14.5 5 6.5 14.5 1.0 1 0 0 1 1 1 0 Osteopontin Pes-10 PF07149.11 CUU97589.1 - 5.1 6.0 6.4 5.9 5.8 6.4 1.1 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 CUU97589.1 - 9.5 4.2 11.2 9.3 4.2 11.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Tetraspanin PF00335.20 CUU97590.1 - 1.2e-07 31.7 1.3 2.4e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Tetraspanin family DUF2852 PF11014.8 CUU97590.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) FAM176 PF14851.6 CUU97590.1 - 0.08 12.6 2.8 0.4 10.3 0.8 2.4 2 0 0 2 2 2 0 FAM176 family RRM_1 PF00076.22 CUU97591.1 - 7.2e-21 73.8 0.2 4.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tryp_FSAP PF08248.11 CUU97591.1 - 2.6 8.8 17.1 9.2 7.1 4.6 2.6 2 0 0 2 2 2 0 Tryptophyllin-3 skin active peptide Tmp39 PF10271.9 CUU97593.1 - 1.4e-47 162.7 14.5 4e-47 161.2 14.5 1.8 1 1 0 1 1 1 1 Putative transmembrane protein Tmp39 PF10271.9 CUU97594.1 - 3.6e-15 55.9 0.4 5.1e-15 55.4 0.4 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 2-Hacid_dh_C PF02826.19 CUU97596.1 - 1.1e-10 41.1 0.0 0.00019 20.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PH_11 PF15413.6 CUU97597.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 CUU97598.1 - 1.2e-05 26.0 3.8 1.6 9.8 0.0 5.6 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU97598.1 - 2.6e-05 24.5 0.0 0.29 11.4 0.0 4.6 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CUU97598.1 - 0.044 13.4 0.1 4.3 6.8 0.0 3.2 3 1 1 4 4 4 0 PQQ-like domain NDUF_B8 PF05821.11 CUU97599.1 - 6.9e-33 114.0 8.1 8.1e-33 113.7 8.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) BCNT PF07572.12 CUU97600.1 - 1.1e-22 79.9 2.9 1.1e-22 79.9 2.9 2.3 2 1 0 2 2 2 1 Bucentaur or craniofacial development FliG_N PF14842.6 CUU97600.1 - 0.028 15.0 0.5 0.063 13.8 0.5 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Roughex PF06020.11 CUU97600.1 - 0.41 9.7 6.7 0.56 9.2 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DMAP_binding PF06464.11 CUU97600.1 - 0.5 11.2 6.3 0.067 14.0 1.8 1.9 2 1 0 2 2 2 0 DMAP1-binding Domain MSC PF09402.10 CUU97600.1 - 1.6 8.1 6.5 1.6 8.1 5.9 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Peptidase_S8 PF00082.22 CUU97601.1 - 2.5e-22 79.5 0.3 3.3e-22 79.1 0.3 1.1 1 0 0 1 1 1 1 Subtilase family ANF_receptor PF01094.28 CUU97602.1 - 3.2e-20 72.5 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region CBM_20 PF00686.19 CUU97602.1 - 0.11 12.4 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Starch binding domain RF3_C PF16658.5 CUU97602.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DUF228 PF02989.14 CUU97604.1 - 0.05 13.4 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function FERM_M PF00373.18 CUU97606.1 - 5.3e-13 49.4 0.3 6.9e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 FERM central domain AbiJ_NTD3 PF18860.1 CUU97606.1 - 0.053 13.0 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 adh_short PF00106.25 CUU97609.1 - 6.8e-20 71.3 0.0 5.6e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CUU97609.1 - 4.3e-14 52.6 0.0 1.6e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.26 CUU97610.1 - 2.9e-05 24.3 13.0 0.0041 17.5 0.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CUU97610.1 - 0.00027 21.2 10.5 0.0097 16.3 1.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CUU97610.1 - 0.0059 17.3 0.5 0.0059 17.3 0.5 3.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-Di19 PF05605.12 CUU97610.1 - 0.0078 16.5 3.4 0.03 14.6 3.4 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CUU97610.1 - 0.017 15.5 0.3 0.017 15.5 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribonuc_red_2_N PF08471.10 CUU97610.1 - 0.037 14.2 0.2 0.094 12.9 0.2 1.6 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase zf-C2H2_9 PF16293.5 CUU97610.1 - 0.048 13.5 1.4 0.35 10.7 0.1 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 CUU97610.1 - 0.055 13.5 0.5 0.055 13.5 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CUU97610.1 - 0.19 12.1 0.1 0.19 12.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CUU97610.1 - 6.8 7.1 7.7 2.7 8.4 3.3 2.5 2 1 0 2 2 2 0 C2H2-type zinc ribbon RYDR_ITPR PF01365.21 CUU97611.1 - 3.1e-23 82.3 0.0 5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 RIH domain RyR PF02026.16 CUU97612.1 - 1.2e-60 201.7 0.1 7e-30 103.1 0.0 2.6 2 0 0 2 2 2 2 RyR domain RYDR_ITPR PF01365.21 CUU97612.1 - 2.8e-50 170.6 0.1 7e-50 169.3 0.0 1.7 2 0 0 2 2 2 1 RIH domain SPRY PF00622.28 CUU97612.1 - 7.2e-44 148.7 0.0 9.3e-19 67.7 0.0 3.5 3 0 0 3 3 3 3 SPRY domain Ins145_P3_rec PF08709.11 CUU97612.1 - 5e-43 146.8 0.0 1.1e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 CUU97612.1 - 1.2e-35 123.0 0.1 7.2e-31 107.5 0.0 2.5 2 0 0 2 2 2 2 MIR domain Pkinase PF00069.25 CUU97613.1 - 8.8e-28 97.4 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU97613.1 - 8.4e-15 54.7 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CUU97613.1 - 3.5e-09 37.2 0.8 8.4e-09 36.0 0.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CUU97613.1 - 0.00068 19.0 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-CCCH PF00642.24 CUU97616.1 - 1.7e-08 34.2 15.7 0.0016 18.3 0.1 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CUU97616.1 - 6.4e-05 22.9 1.7 6.4e-05 22.9 1.7 4.4 5 0 0 5 5 5 1 Zinc finger domain zf-CCCH_3 PF15663.5 CUU97616.1 - 0.0091 16.2 8.7 0.99 9.6 2.4 3.0 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CUU97616.1 - 0.017 14.9 0.3 0.017 14.9 0.3 4.3 4 0 0 4 4 4 0 CCCH-type zinc finger Torus PF16131.5 CUU97616.1 - 0.026 15.2 14.0 0.17 12.6 2.4 3.4 2 1 1 3 3 3 0 Torus domain La PF05383.17 CUU97618.1 - 3.4e-21 75.1 0.1 4.3e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 La domain NPR1_interact PF15699.5 CUU97618.1 - 0.034 14.8 3.0 9.8 6.9 0.0 3.0 3 0 0 3 3 3 0 NPR1 interacting Fibrillarin PF01269.17 CUU97618.1 - 0.29 10.2 0.6 22 4.1 0.1 2.2 2 0 0 2 2 2 0 Fibrillarin Arfaptin PF06456.13 CUU97619.1 - 2.1e-20 73.3 0.8 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Arfaptin-like domain DPCD PF14913.6 CUU97619.1 - 5.4e-06 25.9 0.0 9.2e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 DPCD protein family BAR PF03114.18 CUU97619.1 - 2.7e-05 23.9 1.3 7e-05 22.6 1.3 1.7 1 1 0 1 1 1 1 BAR domain bPH_3 PF14470.6 CUU97621.1 - 0.13 12.7 0.1 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial PH domain DUF1138 PF06592.13 CUU97621.1 - 0.15 12.2 0.1 26 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) fn3 PF00041.21 CUU97625.1 - 7e-09 35.9 0.1 2.8e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 Fibronectin type III domain CRAL_TRIO PF00650.20 CUU97626.1 - 7.2e-20 71.3 0.0 2.1e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain PDZ_4 PF17816.1 CUU97626.1 - 0.05 14.0 0.8 0.26 11.7 0.8 2.2 1 0 0 1 1 1 0 PDZ domain DUF3698 PF12479.8 CUU97626.1 - 0.13 12.8 5.2 1.8 9.1 0.2 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3698) Cnn_1N PF07989.11 CUU97626.1 - 0.17 12.1 55.3 0.43 10.8 13.9 6.9 2 1 1 4 4 4 0 Centrosomin N-terminal motif 1 DUF1902 PF08972.11 CUU97626.1 - 0.18 11.8 0.6 0.74 9.8 0.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) 6PGD PF00393.19 CUU97628.1 - 2.8e-122 407.6 0.0 3.8e-122 407.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CUU97628.1 - 3.1e-36 124.9 0.0 4.9e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ub-Mut7C PF14451.6 CUU97628.1 - 0.036 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin NAD_binding_11 PF14833.6 CUU97628.1 - 0.04 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase STI1 PF17830.1 CUU97628.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 STI1 domain TFIIA_gamma_C PF02751.14 CUU97629.1 - 3.9e-18 65.3 0.1 5.9e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CUU97629.1 - 7.4e-07 29.1 0.1 1.3e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MatE PF01554.18 CUU97630.1 - 3.6e-49 166.5 21.3 8.6e-27 93.8 5.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CUU97630.1 - 0.0086 16.2 0.9 0.0086 16.2 0.9 3.7 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain RNase_H PF00075.24 CUU97630.1 - 0.12 12.6 0.1 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 RNase H HOOK PF05622.12 CUU97631.1 - 8.4e-06 24.2 0.2 8.4e-06 24.2 0.2 2.5 2 1 0 2 2 2 1 HOOK protein DPRP PF04244.13 CUU97631.1 - 0.059 13.2 5.4 0.11 12.4 5.4 1.4 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein SYCE1 PF15233.6 CUU97631.1 - 0.15 12.1 25.3 0.062 13.4 3.0 2.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF749 PF05370.11 CUU97631.1 - 1.6 8.9 5.0 9 6.5 0.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF749) DUF1664 PF07889.12 CUU97631.1 - 5.9 6.9 14.2 0.4 10.7 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Annexin PF00191.20 CUU97634.1 - 6.8e-17 61.3 0.0 4e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 Annexin PTEN_C2 PF10409.9 CUU97635.1 - 3.4e-09 36.6 0.1 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein NAD_synthase PF02540.17 CUU97636.1 - 2e-21 76.3 0.0 9.5e-21 74.0 0.0 2.0 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 CUU97636.1 - 2.6e-17 63.0 0.0 3.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 CUU97636.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Selenoprotein_S PF06936.11 CUU97637.1 - 0.0019 18.0 8.7 0.12 12.1 2.3 2.1 1 1 1 2 2 2 2 Selenoprotein S (SelS) GNAT_acetyltr_2 PF13718.6 CUU97637.1 - 0.018 14.4 0.1 0.023 14.1 0.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CLN3 PF02487.17 CUU97637.1 - 0.21 10.6 0.3 0.25 10.4 0.3 1.0 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 CUU97637.1 - 0.4 9.4 1.0 0.5 9.1 1.0 1.1 1 0 0 1 1 1 0 Presenilin UPF0556 PF10572.9 CUU97638.1 - 6.6e-11 41.9 0.5 8.3e-09 35.1 0.4 2.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0556 TMEM132 PF16070.5 CUU97640.1 - 3e-05 23.5 0.0 0.0013 18.1 0.0 2.5 2 1 0 2 2 2 1 Transmembrane protein family 132 GAT PF03127.14 CUU97642.1 - 5e-22 78.0 3.9 5e-22 78.0 3.9 2.5 2 0 0 2 2 2 2 GAT domain KorB PF08535.10 CUU97642.1 - 0.054 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 KorB domain Ion_trans_2 PF07885.16 CUU97645.1 - 2.3e-26 91.6 6.2 1.7e-17 63.1 1.4 2.2 2 0 0 2 2 2 2 Ion channel DUF4448 PF14610.6 CUU97645.1 - 0.0062 16.3 0.3 0.047 13.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Ion_trans PF00520.31 CUU97645.1 - 0.013 14.8 3.9 0.013 14.8 3.9 1.7 2 0 0 2 2 2 0 Ion transport protein TssN PF17555.2 CUU97645.1 - 0.014 14.8 0.7 0.027 13.9 0.7 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN MFS_Mycoplasma PF07672.13 CUU97645.1 - 0.04 13.2 0.5 0.082 12.2 0.5 1.5 1 0 0 1 1 1 0 Mycoplasma MFS transporter RVT_1 PF00078.27 CUU97651.1 - 3.3e-07 30.0 0.2 1.3e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CUU97652.1 - 3.3e-07 30.0 0.2 1.3e-06 28.1 0.2 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FtsJ PF01728.19 CUU97653.1 - 5.9e-38 130.7 0.0 8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CUU97653.1 - 3.9e-24 85.3 1.0 5.6e-24 84.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) DUF4034 PF13226.6 CUU97656.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) YfhO PF09586.10 CUU97659.1 - 0.022 13.0 1.9 0.029 12.6 1.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ECF_trnsprt PF12822.7 CUU97659.1 - 0.11 12.6 5.0 0.13 12.4 5.0 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Spore_YpjB PF09577.10 CUU97659.1 - 0.16 11.7 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF4059 PF13268.6 CUU97659.1 - 0.24 11.8 8.5 0.19 12.1 6.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4059) GT87 PF09594.10 CUU97659.1 - 0.39 10.4 6.0 0.13 11.9 1.5 1.9 1 1 1 2 2 2 0 Glycosyltransferase family 87 PMP1_2 PF08114.11 CUU97659.1 - 4 7.3 9.1 0.3 10.8 0.8 2.6 2 1 0 2 2 2 0 ATPase proteolipid family SOCS_box PF07525.16 CUU97663.1 - 0.0002 21.7 0.7 0.00056 20.2 0.7 1.8 1 0 0 1 1 1 1 SOCS box Ank_2 PF12796.7 CUU97663.1 - 0.031 14.8 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Forkhead PF00250.18 CUU97664.1 - 1.2e-35 121.7 0.1 2.3e-35 120.7 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain PRIMA1 PF16101.5 CUU97664.1 - 0.0043 17.1 0.6 0.0099 15.9 0.6 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF1648 PF07853.11 CUU97664.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) ESR1_C PF12743.7 CUU97664.1 - 0.12 12.2 4.1 0.47 10.3 4.1 2.0 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Med22 PF06179.12 CUU97665.1 - 5.6e-15 55.4 0.1 7e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex LRR_9 PF14580.6 CUU97666.1 - 8e-72 240.4 2.8 1.1e-71 239.9 2.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CUU97666.1 - 4e-08 32.9 1.3 2.4e-07 30.4 0.5 2.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CUU97666.1 - 9.4e-05 22.7 9.1 0.0028 18.0 1.5 3.7 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CUU97666.1 - 2.1 8.6 7.0 9.3 6.6 0.2 4.6 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_C97 PF05903.14 CUU97667.1 - 3.9e-37 127.4 0.1 5.3e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Sde2_N_Ubi PF13019.6 CUU97668.1 - 6.1e-22 78.2 0.8 1.2e-21 77.2 0.8 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 CUU97668.1 - 3.4e-21 74.7 0.0 6.1e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal Glyco_hydro_79C PF16862.5 CUU97669.1 - 0.038 14.9 1.1 0.11 13.4 0.8 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Neur_chan_memb PF02932.16 CUU97670.1 - 0.0026 17.9 1.9 0.017 15.2 1.9 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DEDD_Tnp_IS110 PF01548.17 CUU97670.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF2207 PF09972.9 CUU97670.1 - 0.21 10.3 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 CUU97670.1 - 0.51 10.5 3.3 2 8.5 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3439 PF11921.8 CUU97670.1 - 2.3 8.2 7.0 8.8 6.3 7.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GDI PF00996.18 CUU97671.1 - 5.9e-12 44.8 0.0 6.8e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ELK PF03789.13 CUU97671.1 - 0.62 10.2 2.6 21 5.3 0.3 2.4 2 0 0 2 2 2 0 ELK domain GDI PF00996.18 CUU97672.1 - 9.2e-16 57.4 0.0 1.2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor RGS_DHEX PF18148.1 CUU97673.1 - 1.3e-34 118.3 1.8 1.4e-34 118.1 0.7 1.6 2 0 0 2 2 2 1 Regulator of G-protein signalling DHEX domain RGS PF00615.19 CUU97673.1 - 1.1e-31 109.6 1.1 2e-31 108.7 1.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 CUU97673.1 - 2.5e-12 46.7 0.0 7.3e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TMEM100 PF16311.5 CUU97680.1 - 0.066 12.8 0.2 0.093 12.3 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 SNARE_assoc PF09335.11 CUU97680.1 - 0.12 12.9 7.3 0.79 10.2 0.9 2.1 1 1 1 2 2 2 0 SNARE associated Golgi protein PDZ_6 PF17820.1 CUU97681.1 - 0.00091 19.0 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CUU97681.1 - 0.0076 16.6 0.0 0.028 14.7 0.0 1.9 2 1 0 2 2 2 1 PDZ domain Methyltransf_15 PF09445.10 CUU97682.1 - 0.00023 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MCU PF04678.13 CUU97687.1 - 6.2 6.9 10.3 1.9e+02 2.1 10.3 2.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Ion_trans_2 PF07885.16 CUU97690.1 - 0.43 10.6 3.8 0.25 11.3 0.5 2.1 2 0 0 2 2 2 0 Ion channel Exo_endo_phos_2 PF14529.6 CUU97691.1 - 5.2e-12 45.7 0.5 8.8e-12 44.9 0.5 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase YtpI PF14007.6 CUU97692.1 - 0.012 15.7 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 YtpI-like protein Oxidored_q2 PF00420.24 CUU97692.1 - 0.035 13.7 0.2 0.048 13.3 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tetraspanin PF00335.20 CUU97692.1 - 0.41 10.3 2.2 0.56 9.9 2.2 1.2 1 0 0 1 1 1 0 Tetraspanin family PHD PF00628.29 CUU97693.1 - 4.1e-13 49.0 3.8 4.1e-13 49.0 3.8 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CUU97693.1 - 0.013 15.4 1.0 0.032 14.2 1.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CUU97693.1 - 0.018 14.6 0.9 0.018 14.6 0.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 CUU97693.1 - 0.15 12.4 5.6 0.61 10.5 5.6 2.1 1 0 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 CUU97693.1 - 0.55 10.6 8.5 0.27 11.6 5.7 2.0 2 0 0 2 2 2 0 C1 domain zf-ANAPC11 PF12861.7 CUU97693.1 - 0.72 9.9 5.1 2.1 8.5 5.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 CUU97693.1 - 1.6 9.0 8.0 0.38 11.0 3.8 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain VMA21 PF09446.10 CUU97696.1 - 0.12 12.4 3.0 0.22 11.7 3.0 1.6 1 1 0 1 1 1 0 VMA21-like domain SCAMP PF04144.13 CUU97697.1 - 0.0095 16.3 3.0 0.014 15.7 3.0 1.3 1 0 0 1 1 1 1 SCAMP family Dynein_light PF01221.18 CUU97698.1 - 2.2e-18 66.4 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Parvo_NS1 PF01057.17 CUU97699.1 - 5.8e-15 55.1 0.1 9.2e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CUU97699.1 - 6.3e-06 25.3 0.0 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase TRP_2 PF08344.11 CUU97700.1 - 2.5e-20 72.4 1.2 6.4e-20 71.1 1.2 1.8 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CUU97700.1 - 2.4e-09 37.6 3.7 0.00015 22.3 0.3 3.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CUU97700.1 - 6.1e-07 29.3 1.9 0.011 16.2 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 CUU97700.1 - 2.6e-06 27.9 0.1 0.09 13.4 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CUU97700.1 - 5.6e-05 23.4 1.7 0.00077 19.8 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ribonuclease_T2 PF00445.18 CUU97700.1 - 0.00029 21.1 0.0 1.1 9.5 0.0 2.3 1 1 1 2 2 2 2 Ribonuclease T2 family Ank_5 PF13857.6 CUU97700.1 - 0.00041 20.6 0.1 0.25 11.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PPARgamma_N PF12577.8 CUU97700.1 - 0.031 14.9 0.1 18 6.0 0.0 2.5 2 0 0 2 2 2 0 PPAR gamma N-terminal region DUF5318 PF17249.2 CUU97700.1 - 0.04 13.7 0.3 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5318) RP854 PF17460.2 CUU97700.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein RP854 EF-hand_1 PF00036.32 CUU97701.1 - 1.5e-08 33.6 1.6 0.00076 18.9 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CUU97701.1 - 5.9e-08 32.4 0.8 9.7e-08 31.8 0.8 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 CUU97701.1 - 7.1e-08 32.8 2.7 1.2e-07 32.1 2.7 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CUU97701.1 - 0.00013 21.6 2.0 0.013 15.4 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CUU97701.1 - 0.00036 19.9 0.2 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CUU97701.1 - 0.0088 16.4 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Aldo_ket_red PF00248.21 CUU97704.1 - 4.3e-18 65.5 0.0 1.2e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family eIF_4EBP PF05456.11 CUU97705.1 - 0.081 12.9 0.7 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Hydrolase_4 PF12146.8 CUU97710.1 - 6e-12 45.3 0.3 1.1e-06 28.1 0.1 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CUU97710.1 - 1.8e-06 28.8 3.0 1.6e-05 25.6 0.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CUU97710.1 - 1e-05 25.3 0.2 0.03 14.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CUU97710.1 - 4.5e-05 23.0 0.0 0.00066 19.2 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 CUU97710.1 - 0.00018 20.6 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 CUU97710.1 - 0.043 13.4 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.22 CUU97710.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Cutinase Abhydrolase_5 PF12695.7 CUU97710.1 - 0.13 12.1 0.0 0.37 10.5 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hamartin PF04388.12 CUU97710.1 - 8.5 4.9 16.9 12 4.4 16.9 1.1 1 0 0 1 1 1 0 Hamartin protein SprA-related PF12118.8 CUU97710.1 - 8.9 5.3 14.8 1.1 8.4 9.7 1.7 1 1 1 2 2 2 0 SprA-related family SprA-related PF12118.8 CUU97711.1 - 3.3 6.8 17.1 13 4.8 17.1 1.8 1 1 0 1 1 1 0 SprA-related family Hamartin PF04388.12 CUU97711.1 - 9.6 4.7 19.7 11 4.5 19.7 1.1 1 0 0 1 1 1 0 Hamartin protein Pirin_C PF05726.13 CUU97713.1 - 0.11 12.8 0.0 5.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Pirin C-terminal cupin domain Mitoc_L55 PF09776.9 CUU97713.1 - 0.18 11.6 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 UNC119_bdg PF15435.6 CUU97715.1 - 0.031 13.8 0.9 0.31 10.6 0.1 2.1 1 1 1 2 2 2 0 UNC119-binding protein C5orf30 homologue Sybindin PF04099.12 CUU97716.1 - 2.1e-23 82.8 0.1 2.4e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family DUF1563 PF07599.11 CUU97716.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ABC_membrane PF00664.23 CUU97717.1 - 3e-56 191.1 36.2 4.3e-33 115.1 14.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CUU97717.1 - 6.3e-43 146.6 0.0 2.8e-24 86.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CUU97717.1 - 1.1e-11 44.6 0.2 1e-06 28.4 0.2 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CUU97717.1 - 2.3e-08 34.2 0.0 0.035 13.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CUU97717.1 - 4.4e-07 30.0 0.0 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 CUU97717.1 - 0.00023 21.4 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 CUU97717.1 - 0.0019 17.9 0.5 0.55 10.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 CUU97717.1 - 0.0024 18.0 1.3 0.25 11.4 0.2 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CUU97717.1 - 0.0036 17.2 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CUU97717.1 - 0.004 17.6 0.1 0.65 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CUU97717.1 - 0.052 13.8 0.8 2.9 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 CUU97717.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.6 CUU97717.1 - 0.21 12.1 2.1 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain EF-hand_7 PF13499.6 CUU97719.1 - 8.3e-23 80.6 0.3 6.5e-15 55.3 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CUU97719.1 - 4.3e-21 72.8 1.5 2.1e-07 30.0 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CUU97719.1 - 1e-17 62.4 1.8 8.1e-05 22.2 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CUU97719.1 - 2.2e-15 56.2 1.7 0.0075 16.1 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CUU97719.1 - 3.8e-15 54.6 1.7 9.1e-06 24.9 0.0 4.5 4 0 0 4 4 4 3 EF hand Dockerin_1 PF00404.18 CUU97719.1 - 4.9e-05 23.4 0.1 0.0012 19.0 0.1 2.3 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_9 PF14658.6 CUU97719.1 - 0.00037 20.8 0.1 0.0053 17.1 0.0 2.7 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CUU97719.1 - 0.00043 20.6 0.0 0.067 13.5 0.0 3.1 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CUU97719.1 - 0.098 12.6 0.8 36 4.2 0.0 3.2 2 1 1 3 3 3 0 Caleosin related protein VCBS PF13517.6 CUU97719.1 - 2.6 8.7 4.6 2.9 8.6 1.9 2.5 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PWI PF01480.17 CUU97721.1 - 2.9e-21 75.6 0.0 5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 PWI domain P_proprotein PF01483.20 CUU97724.1 - 2.2e-12 46.8 0.1 3.6e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Ras PF00071.22 CUU97725.1 - 3.8e-55 185.9 0.0 4.3e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CUU97725.1 - 1.1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CUU97725.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CUU97725.1 - 0.00019 21.4 0.9 0.18 11.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CUU97725.1 - 0.0028 17.2 0.2 0.02 14.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CUU97725.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 CUU97725.1 - 0.022 13.9 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 CUU97725.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin Ank_2 PF12796.7 CUU97727.1 - 9.7e-25 87.0 0.0 6.6e-14 52.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU97727.1 - 6.3e-15 55.3 0.5 1e-08 35.5 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CUU97727.1 - 1.4e-12 47.5 6.2 2.9e-06 27.4 0.2 4.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CUU97727.1 - 4.7e-12 45.9 2.9 0.0051 17.1 0.0 5.3 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU97727.1 - 3.4e-11 42.3 1.1 0.00034 20.8 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat CaKB PF03185.15 CUU97728.1 - 2.6e-06 27.2 0.1 3.4e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit DUF3496 PF12001.8 CUU97729.1 - 0.0056 17.0 0.5 0.0096 16.3 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3496) UEV PF05743.13 CUU97732.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain gag-asp_proteas PF13975.6 CUU97733.1 - 0.072 13.7 0.0 0.24 12.0 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CUU97733.1 - 0.19 12.4 0.0 0.54 10.9 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF2999 PF11212.8 CUU97735.1 - 0.059 13.7 0.0 0.093 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) WD40 PF00400.32 CUU97739.1 - 1.3e-09 38.5 0.4 2.1e-08 34.7 0.2 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Metallophos PF00149.28 CUU97748.1 - 3.7e-08 34.1 0.1 9.8e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fer4_9 PF13187.6 CUU97748.1 - 4.5 7.5 7.1 19 5.5 1.3 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Tautomerase_2 PF14552.6 CUU97750.1 - 0.17 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Tautomerase enzyme zf-Tim10_DDP PF02953.15 CUU97752.1 - 1e-24 85.9 3.3 1.4e-24 85.5 3.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Arg_decarbox_C PF17944.1 CUU97752.1 - 0.029 14.9 0.2 2.1 8.9 0.1 2.8 2 1 1 3 3 3 0 Arginine decarboxylase C-terminal helical extension DUF3128 PF11326.8 CUU97753.1 - 0.093 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) CD4-extracel PF09191.10 CUU97754.1 - 0.055 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 CD4, extracellular Glycos_transf_2 PF00535.26 CUU97758.1 - 9.4e-25 87.4 0.0 1.3e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CUU97758.1 - 6.5e-07 29.1 0.0 9.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CUU97758.1 - 1.1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CUU97758.1 - 0.0037 17.8 0.0 0.0095 16.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Malectin PF11721.8 CUU97758.1 - 0.062 13.4 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 Malectin domain GNT-I PF03071.15 CUU97758.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 GNT-I family Fungal_trans PF04082.18 CUU97759.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_2 PF07719.17 CUU97761.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CUU97766.1 - 0.039 14.0 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat PMI_typeI PF01238.21 CUU97768.1 - 0.06 12.5 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I DUF4497 PF14924.6 CUU97770.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) CH PF00307.31 CUU97771.1 - 3.5e-44 149.5 0.1 2e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Calponin PF00402.18 CUU97771.1 - 5e-09 35.6 2.7 7.9e-09 35.0 2.7 1.3 1 0 0 1 1 1 1 Calponin family repeat CDC24 PF06395.11 CUU97771.1 - 1.3e-06 28.5 0.7 0.07 13.4 0.1 2.3 2 0 0 2 2 2 2 CDC24 Calponin CAMSAP_CH PF11971.8 CUU97771.1 - 2.9e-06 27.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 CAMSAP CH domain Phage_gp53 PF11246.8 CUU97771.1 - 0.0012 18.6 0.2 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Base plate wedge protein 53 Arc_PepC PF06819.11 CUU97771.1 - 0.002 18.2 0.9 0.89 9.7 0.1 2.3 2 0 0 2 2 2 2 Archaeal Peptidase A24 C-terminal Domain CcmE PF03100.15 CUU97771.1 - 0.0042 17.1 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 2 CcmE EFG_IV PF03764.18 CUU97771.1 - 0.0046 16.7 0.1 3.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor G, domain IV Chalcone PF02431.15 CUU97771.1 - 0.017 14.5 0.1 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Chalcone-flavanone isomerase ICMT PF04140.14 CUU97771.1 - 0.042 14.3 0.0 16 6.0 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family UAF_Rrn10 PF05234.11 CUU97771.1 - 0.13 12.5 0.1 25 5.1 0.0 2.3 2 0 0 2 2 2 0 UAF complex subunit Rrn10 FYVE PF01363.21 CUU97772.1 - 2.3e-20 72.5 10.2 7.9e-20 70.8 10.2 2.0 1 0 0 1 1 1 1 FYVE zinc finger DUF812 PF05667.11 CUU97772.1 - 0.0021 17.1 37.4 0.0021 17.1 37.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF812) NPV_P10 PF05531.12 CUU97772.1 - 0.0034 17.8 10.3 0.026 15.0 0.8 3.4 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 CUU97772.1 - 0.0036 16.9 20.3 0.0036 16.9 20.3 3.0 1 1 1 3 3 3 1 PspA/IM30 family CLZ PF16526.5 CUU97772.1 - 0.0099 16.2 2.1 0.0099 16.2 2.1 4.5 2 2 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RUN PF02759.19 CUU97772.1 - 0.041 13.8 8.2 2.4 8.1 0.0 4.4 3 2 0 3 3 2 0 RUN domain DUF1664 PF07889.12 CUU97772.1 - 0.14 12.2 23.1 0.29 11.2 2.9 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CUU97772.1 - 1 9.6 57.6 0.37 11.0 8.2 4.3 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) V-SNARE_C PF12352.8 CUU97772.1 - 1 9.7 9.9 0.48 10.8 0.4 3.4 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF3584 PF12128.8 CUU97772.1 - 1.9 5.9 42.5 2.7 5.4 42.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PI_PP_I PF18363.1 CUU97772.1 - 2.2 8.5 5.5 4.2 7.6 1.3 2.7 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain zf-B_box PF00643.24 CUU97772.1 - 4.4 7.5 11.5 1.2 9.3 6.4 2.4 2 0 0 2 2 2 0 B-box zinc finger Spc7 PF08317.11 CUU97772.1 - 4.7 6.0 51.2 1.6 7.5 15.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 CUU97772.1 - 4.7 6.9 43.7 0.091 12.5 22.3 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 CUU97772.1 - 5.2 6.3 40.2 0.015 14.6 16.0 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 CUU97772.1 - 8.1 6.8 33.6 0.11 12.8 2.8 4.4 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bcr-Abl_Oligo PF09036.10 CUU97772.1 - 8.3 6.5 13.7 1.6 8.8 2.2 3.7 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF948 PF06103.11 CUU97772.1 - 9.8 6.5 9.4 5.5 7.3 0.4 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) RRM_1 PF00076.22 CUU97773.1 - 9.3e-08 31.8 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CUU97773.1 - 3.8e-06 26.9 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif ubiquitin PF00240.23 CUU97776.1 - 2.6e-13 49.5 0.4 3.4e-13 49.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CUU97776.1 - 9.7e-07 28.5 0.1 1.3e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CUU97776.1 - 0.0017 18.8 0.0 0.0023 18.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CUU97776.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Yos1 PF08571.10 CUU97777.1 - 4.2e-20 71.8 0.2 4.8e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Yos1-like cNMP_binding PF00027.29 CUU97778.1 - 2.9e-17 62.5 0.1 6.8e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain YDG PF18657.1 CUU97781.1 - 0.02 15.1 0.4 0.039 14.1 0.4 1.4 1 0 0 1 1 1 0 YDG domain ExbD PF02472.16 CUU97785.1 - 0.055 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Nairovirus_M PF07948.11 CUU97786.1 - 0.077 11.2 0.0 0.091 11.0 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like CH PF00307.31 CUU97787.1 - 1.5e-20 73.4 0.0 2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CUU97787.1 - 1.7e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 CUU97787.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein YdjC PF04794.12 CUU97788.1 - 3.8e-48 164.5 0.0 4.4e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MMR_HSR1 PF01926.23 CUU97791.1 - 9.5e-16 57.9 0.0 8.6e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CUU97791.1 - 1e-10 41.3 0.0 4.9e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CUU97791.1 - 5.8e-08 32.8 1.6 0.019 14.9 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase Dynamin_N PF00350.23 CUU97791.1 - 0.027 14.5 0.4 0.91 9.6 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Ribosomal_S11 PF00411.19 CUU97794.1 - 8.6e-19 68.0 0.5 1.3e-18 67.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Bromodomain PF00439.25 CUU97795.1 - 2.5e-17 62.7 0.1 8.1e-17 61.1 0.1 1.9 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 CUU97795.1 - 6e-05 22.7 3.1 0.0062 16.0 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3512) DUF5498 PF17602.2 CUU97795.1 - 0.13 12.8 0.5 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5498) Aminotran_MocR PF12897.7 CUU97795.1 - 0.18 10.6 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase HSCB_C PF07743.13 CUU97796.1 - 1.4e-13 51.1 1.0 3.1e-13 50.0 0.5 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CUU97796.1 - 0.00029 20.9 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1539 PF07560.11 CUU97796.1 - 0.0083 16.2 0.6 0.018 15.1 0.2 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) DUF3079 PF11278.8 CUU97796.1 - 0.047 13.5 0.6 0.091 12.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) SlyX PF04102.12 CUU97797.1 - 0.091 13.4 0.3 0.091 13.4 0.3 9.3 6 3 3 9 9 9 0 SlyX PilX_N PF14341.6 CUU97800.1 - 0.24 11.4 0.2 0.83 9.7 0.1 1.8 2 0 0 2 2 2 0 PilX N-terminal MIP PF00230.20 CUU97802.1 - 2.1e-16 60.3 0.5 2.6e-16 60.0 0.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein cNMP_binding PF00027.29 CUU97803.1 - 8.3e-20 70.7 0.0 1.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CUU97803.1 - 1.2e-18 67.3 14.8 2.3e-18 66.4 14.8 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CUU97803.1 - 0.00099 19.0 0.2 0.0026 17.7 0.2 1.7 1 0 0 1 1 1 1 Ion channel DUF4385 PF14328.6 CUU97804.1 - 0.01 15.9 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) Sid-5 PF17204.3 CUU97804.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Sid-5 family Death PF00531.22 CUU97808.1 - 5.8e-06 26.4 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Death domain TTSSLRR PF12468.8 CUU97808.1 - 0.00028 21.1 0.0 2.3 8.5 0.0 3.3 2 0 0 2 2 2 2 Type III secretion system leucine rich repeat protein SF3a60_bindingd PF12108.8 CUU97808.1 - 0.084 12.8 1.4 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain AHD PF17793.1 CUU97808.1 - 0.093 12.5 0.4 24 4.8 0.0 2.8 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Arg_decarbox_C PF17944.1 CUU97808.1 - 0.58 10.8 7.1 18 6.0 0.0 4.2 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension Toluene_X PF03349.16 CUU97812.1 - 0.0061 15.2 0.2 0.0066 15.1 0.2 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) Fasciclin PF02469.22 CUU97813.1 - 0.00072 19.8 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain EF-hand_1 PF00036.32 CUU97814.1 - 1.2e-32 109.0 3.7 2.8e-07 29.6 0.0 5.1 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 CUU97814.1 - 8.7e-29 99.8 0.9 2e-11 44.2 0.2 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CUU97814.1 - 2.1e-24 83.3 3.5 2.2e-06 27.2 0.0 5.1 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 CUU97814.1 - 2.7e-20 70.9 6.7 0.00033 20.0 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 CUU97814.1 - 4e-13 49.0 4.7 0.00042 20.1 0.0 4.5 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CUU97814.1 - 6.5e-05 23.2 0.0 0.58 10.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CUU97814.1 - 7.7e-05 22.6 1.2 0.068 13.1 0.0 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CUU97814.1 - 0.00087 19.1 0.6 1.9 8.4 0.0 3.4 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 CUU97814.1 - 0.01 16.2 0.4 5.6 7.3 0.0 2.8 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CUU97814.1 - 0.034 14.5 0.2 6.2 7.2 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain zf-LITAF-like PF10601.9 CUU97815.1 - 6.1e-24 84.1 14.3 8.6e-24 83.6 14.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_7 PF02591.15 CUU97815.1 - 0.00054 20.1 8.7 0.14 12.4 2.2 2.5 2 0 0 2 2 2 2 C4-type zinc ribbon domain Sgf11 PF08209.11 CUU97815.1 - 0.013 15.0 2.3 0.6 9.7 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_jaz PF12171.8 CUU97815.1 - 0.084 13.2 0.4 7.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UPF0547 PF10571.9 CUU97815.1 - 0.14 12.3 0.7 0.14 12.3 0.7 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 YacG PF03884.14 CUU97815.1 - 1.3 8.8 12.9 4.2 7.2 0.4 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Kunitz_BPTI PF00014.23 CUU97821.1 - 2e-13 50.3 4.2 3.1e-13 49.7 4.2 1.3 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain ApoLp-III PF07464.11 CUU97823.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MRP-S22 PF10245.9 CUU97824.1 - 9.7e-83 277.6 0.4 1.2e-82 277.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 DUF608 PF04685.13 CUU97825.1 - 6e-123 410.6 3.2 7.8e-123 410.2 3.2 1.1 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Peptidase_C31 PF05410.13 CUU97825.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha MutS_V PF00488.21 CUU97826.1 - 2.9e-62 210.0 0.7 9.4e-62 208.4 0.1 2.1 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CUU97826.1 - 3.1e-05 24.3 0.0 6.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.6 CUU97826.1 - 0.025 14.3 0.3 0.061 13.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.18 CUU97826.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.6 CUU97826.1 - 0.19 12.2 0.2 0.45 11.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain Glyco_tran_28_C PF04101.16 CUU97827.1 - 3.5e-20 72.6 0.0 4.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Tetraspanin PF00335.20 CUU97832.1 - 0.0032 17.2 0.0 0.0037 17.0 0.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Rab5ip PF07019.12 CUU97833.1 - 8.6e-10 39.1 1.8 1e-09 38.8 1.8 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TFIIA PF03153.13 CUU97835.1 - 0.43 10.5 11.4 0.48 10.4 11.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C4 PF00105.18 CUU97838.1 - 2.7e-10 40.5 4.9 2.7e-10 40.5 4.9 1.8 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.9 CUU97838.1 - 0.01 15.9 0.4 0.015 15.4 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_1 PF00130.22 CUU97838.1 - 0.038 13.9 3.0 0.085 12.8 3.0 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CUU97838.1 - 0.097 12.6 0.4 0.097 12.6 0.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 CUU97838.1 - 0.19 11.7 3.1 0.22 11.5 3.1 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-ribbon_3 PF13248.6 CUU97838.1 - 0.5 9.9 4.2 26 4.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain C1_2 PF03107.16 CUU97838.1 - 0.6 10.5 4.1 1.1 9.6 4.1 1.5 1 1 0 1 1 1 0 C1 domain zf-UDP PF14569.6 CUU97838.1 - 1.4 9.1 5.7 5 7.3 1.1 2.4 1 1 2 3 3 3 0 Zinc-binding RING-finger SNAP-25 PF00835.19 CUU97840.1 - 7.6e-09 35.7 0.4 2.3e-08 34.2 0.4 1.9 1 0 0 1 1 1 1 SNAP-25 family DUF16 PF01519.16 CUU97840.1 - 0.0005 20.5 4.8 0.12 12.9 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF16 DUF5089 PF17002.5 CUU97840.1 - 0.00057 19.8 3.3 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) DASH_Duo1 PF08651.10 CUU97840.1 - 0.00083 19.1 2.8 0.19 11.5 0.0 2.9 2 1 1 3 3 3 2 DASH complex subunit Duo1 V-SNARE_C PF12352.8 CUU97840.1 - 0.0066 16.7 2.3 0.54 10.6 0.0 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.12 CUU97840.1 - 0.035 14.1 5.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Laminin Domain II SNARE PF05739.19 CUU97840.1 - 0.12 12.4 0.5 0.12 12.4 0.5 3.0 3 0 0 3 3 3 0 SNARE domain Spectrin PF00435.21 CUU97840.1 - 0.14 12.7 4.0 1.4 9.4 1.2 2.3 2 0 0 2 2 2 0 Spectrin repeat DUF948 PF06103.11 CUU97840.1 - 0.15 12.3 3.7 16 5.8 0.4 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FAM25 PF15825.5 CUU97840.1 - 0.16 12.3 1.5 0.5 10.7 0.2 2.2 3 0 0 3 3 2 0 FAM25 family Jnk-SapK_ap_N PF09744.9 CUU97840.1 - 0.19 11.9 4.2 0.094 12.9 1.3 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DASH_Dad4 PF08650.10 CUU97840.1 - 0.21 11.6 1.9 1.9 8.5 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad4 WXG100 PF06013.12 CUU97840.1 - 1.2 9.4 7.8 6.2 7.1 0.2 3.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 CUU97840.1 - 1.2 9.2 5.1 9.7 6.3 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CUU97840.1 - 2.3 8.9 6.9 20 5.9 1.6 2.7 2 1 0 2 2 2 0 SlyX SOAR PF16533.5 CUU97840.1 - 2.6 8.1 6.6 12 6.0 0.0 2.8 2 1 1 3 3 3 0 STIM1 Orai1-activating region XhlA PF10779.9 CUU97840.1 - 5.4 7.3 11.7 2.3 8.5 1.5 2.8 3 0 0 3 3 3 0 Haemolysin XhlA DivIC PF04977.15 CUU97840.1 - 6.9 6.5 8.7 2.6 7.9 0.5 2.4 2 1 0 2 2 2 0 Septum formation initiator 60KD_IMP PF02096.20 CUU97843.1 - 0.00069 19.6 1.2 0.0067 16.3 1.2 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein RVP PF00077.20 CUU97844.1 - 5.1e-05 23.5 0.0 6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CUU97844.1 - 5.3e-05 23.7 0.0 5.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CUU97844.1 - 0.00044 20.8 0.0 0.00048 20.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DTHCT PF08070.11 CUU97845.1 - 0.036 14.8 13.3 0.04 14.7 3.9 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region SR-25 PF10500.9 CUU97845.1 - 3 7.4 24.7 0.091 12.4 6.2 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1129 PF06570.11 CUU97847.1 - 0.14 11.6 1.3 0.16 11.5 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) OAD_gamma PF04277.13 CUU97847.1 - 0.16 12.6 0.1 0.19 12.3 0.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UCR_14kD PF02271.16 CUU97848.1 - 0.07 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF2423 PF10338.9 CUU97848.1 - 0.12 12.6 0.1 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) PPTA PF01239.22 CUU97850.1 - 9.8e-36 120.5 18.7 1.7e-09 37.1 0.3 6.3 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.7 CUU97850.1 - 4.1e-08 33.4 7.9 0.0012 19.1 0.2 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CUU97850.1 - 8.1e-07 28.7 2.6 5.2e-05 22.9 1.0 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CUU97850.1 - 0.00012 21.7 1.8 0.00021 20.8 0.3 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CUU97850.1 - 0.041 13.9 5.5 3.1 8.1 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CUU97850.1 - 0.23 12.1 5.7 1.1e+02 4.0 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LsmAD PF06741.13 CUU97851.1 - 3e-15 56.5 0.3 6.9e-15 55.3 0.3 1.7 1 0 0 1 1 1 1 LsmAD domain EzrA PF06160.12 CUU97851.1 - 0.09 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ion_trans_2 PF07885.16 CUU97852.1 - 6.1e-34 115.8 15.6 1.1e-17 63.8 0.8 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CUU97852.1 - 1.9e-08 33.9 1.5 0.0037 16.5 0.0 2.3 1 1 1 2 2 2 2 Ion transport protein PAXX PF15384.6 CUU97853.1 - 0.014 15.1 0.9 0.14 11.8 0.9 2.0 1 1 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Spiralin PF05215.13 CUU97853.1 - 0.041 13.2 0.1 0.054 12.8 0.1 1.1 1 0 0 1 1 1 0 Spiralin LAGLIDADG_1 PF00961.19 CUU97853.1 - 0.05 14.6 0.5 0.19 12.7 0.1 1.9 2 0 0 2 2 2 0 LAGLIDADG endonuclease NAP PF00956.18 CUU97854.1 - 7.7e-29 100.7 36.7 2.9e-18 66.0 7.8 6.9 5 3 1 6 6 6 4 Nucleosome assembly protein (NAP) DUF98 PF01947.16 CUU97854.1 - 0.068 13.1 3.8 0.36 10.8 0.8 2.2 2 0 0 2 2 2 0 p-hydroxybenzoic acid synthase Mst1_SARAH PF11629.8 CUU97854.1 - 0.38 10.9 3.9 7.6 6.7 0.1 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Abhydrolase_2 PF02230.16 CUU97855.1 - 5.7e-67 225.7 0.0 7.3e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CUU97855.1 - 7.2e-07 28.7 0.0 0.041 13.1 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CUU97855.1 - 1.9e-05 24.4 0.8 0.26 10.9 0.1 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.18 CUU97855.1 - 3.4e-05 23.5 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CUU97855.1 - 7.4e-05 23.5 0.0 8.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CUU97855.1 - 0.00063 19.3 0.0 0.15 11.5 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 CUU97855.1 - 0.009 15.7 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CUU97855.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CUU97855.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.13 CUU97855.1 - 0.028 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) RNase_PH PF01138.21 CUU97856.1 - 8.1e-14 52.2 0.0 8.1e-14 52.2 0.0 3.0 4 0 0 4 4 4 1 3' exoribonuclease family, domain 1 S1 PF00575.23 CUU97856.1 - 1.4e-11 44.6 0.4 1.4e-11 44.6 0.4 2.7 3 1 0 3 3 3 1 S1 RNA binding domain zf-CCHC_2 PF13696.6 CUU97856.1 - 0.0029 17.4 1.1 0.0073 16.1 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF1492 PF07374.11 CUU97856.1 - 0.0043 17.2 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1492) zf-CCHC_5 PF14787.6 CUU97856.1 - 0.014 15.1 0.2 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CUU97856.1 - 0.042 13.8 0.3 0.092 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CUU97856.1 - 0.059 13.5 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 CUU97856.1 - 1.6 7.9 4.5 2.2 7.4 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.32 CUU97857.1 - 3e-07 31.0 5.8 1.6 9.7 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU97857.1 - 2.5e-06 27.7 0.0 1 9.7 0.0 3.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CUU97857.1 - 1.3e-05 25.2 0.0 0.00012 22.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CUU97857.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 CUU97857.1 - 0.061 13.3 0.2 29 4.7 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CUU97857.1 - 0.21 10.5 0.0 0.43 9.5 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-LITAF-like PF10601.9 CUU97858.1 - 5e-23 81.1 10.1 9e-23 80.3 10.1 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain GFA PF04828.14 CUU97858.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.4 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4451 PF14616.6 CUU97858.1 - 0.09 13.0 0.2 0.09 13.0 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) zf-RING_7 PF02591.15 CUU97858.1 - 0.12 12.5 8.1 0.36 11.1 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain NOB1_Zn_bind PF08772.11 CUU97858.1 - 0.25 11.5 0.2 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 CUU97858.1 - 0.41 10.4 12.4 8.5 6.2 0.0 3.2 2 1 0 2 2 2 0 zinc-ribbon domain YacG PF03884.14 CUU97858.1 - 0.62 9.8 12.0 4.4 7.1 4.6 3.3 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf_C2H2_10 PF18414.1 CUU97858.1 - 1.5 8.4 12.5 2.4 7.8 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-LITAF-like PF10601.9 CUU97859.1 - 1.8e-23 82.6 9.3 1.8e-23 82.6 9.3 1.8 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain zf-C2H2_6 PF13912.6 CUU97859.1 - 0.59 10.2 0.0 0.59 10.2 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU97859.1 - 0.69 10.4 9.7 13 6.4 2.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Prominin PF05478.11 CUU97859.1 - 1 7.2 7.1 1.1 7.1 7.1 1.0 1 0 0 1 1 1 0 Prominin LIM PF00412.22 CUU97860.1 - 1.8e-52 175.4 46.9 4.4e-14 52.4 2.7 4.2 4 0 0 4 4 4 4 LIM domain ADK_lid PF05191.14 CUU97860.1 - 0.79 9.8 12.2 26 4.9 0.1 5.8 5 0 0 5 5 5 0 Adenylate kinase, active site lid LIM PF00412.22 CUU97861.1 - 1.8e-52 175.4 46.9 4.5e-14 52.4 2.7 4.2 4 0 0 4 4 4 4 LIM domain ADK_lid PF05191.14 CUU97861.1 - 0.74 9.9 12.2 27 4.9 0.1 5.9 5 0 0 5 5 5 0 Adenylate kinase, active site lid Halogen_Hydrol PF10112.9 CUU97862.1 - 0.058 13.4 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF5066 PF16728.5 CUU97863.1 - 8e-10 38.4 1.3 0.032 13.6 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF5066) Tau95_N PF17682.1 CUU97863.1 - 0.00013 22.2 0.4 11 6.2 0.0 3.3 3 0 0 3 3 3 3 Tau95 Triple barrel domain DUF4872 PF16169.5 CUU97863.1 - 0.00035 20.4 0.0 14 5.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4872) CTD PF12815.7 CUU97863.1 - 0.0012 19.3 0.3 3.7 8.2 0.0 4.0 3 1 0 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DFF40 PF09230.10 CUU97863.1 - 0.0049 16.5 0.3 23 4.5 0.0 3.0 3 0 0 3 3 3 0 DNA fragmentation factor 40 kDa DUF1667 PF07892.11 CUU97863.1 - 0.0059 16.6 3.8 21 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1667) tify PF06200.14 CUU97863.1 - 0.006 15.9 9.7 5 6.5 0.2 4.2 4 0 0 4 4 4 3 tify domain KilA-N PF04383.13 CUU97863.1 - 0.0073 16.1 5.9 11 5.9 0.1 3.4 3 0 0 3 3 3 3 KilA-N domain DMAP_binding PF06464.11 CUU97863.1 - 0.19 12.6 5.6 68 4.3 0.1 3.9 4 0 0 4 4 3 0 DMAP1-binding Domain DUF2877 PF11392.8 CUU97863.1 - 0.2 12.4 0.1 2.1e+02 2.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) MltA PF03562.17 CUU97863.1 - 0.48 10.2 17.6 9.1 6.0 0.2 5.5 1 1 1 3 3 3 0 MltA specific insert domain zinc_ribbon_4 PF13717.6 CUU97863.1 - 0.66 10.0 6.6 2.1e+02 2.0 0.0 5.7 7 0 0 7 7 7 0 zinc-ribbon domain DUF4441 PF14536.6 CUU97863.1 - 0.73 10.0 4.0 64 3.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Lig_C PF18330.1 CUU97863.1 - 1 9.3 3.3 1.1e+02 2.8 0.1 3.1 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region Pollen_allerg_1 PF01357.21 CUU97864.1 - 0.0065 16.5 0.1 3.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Pollen allergen Flagellin_IN PF07196.13 CUU97864.1 - 0.13 12.5 0.8 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Flagellin hook IN motif CIDE-N PF02017.15 CUU97864.1 - 0.16 12.0 0.1 22 5.2 0.0 2.4 2 0 0 2 2 2 0 CIDE-N domain TRAM_LAG1_CLN8 PF03798.16 CUU97869.1 - 2.4e-29 102.5 25.4 2.4e-29 102.5 25.4 2.1 1 1 0 2 2 2 2 TLC domain RT_RNaseH_2 PF17919.1 CUU97870.1 - 4.5e-06 26.6 0.0 5.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CUU97870.1 - 0.0032 17.7 0.0 0.0034 17.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase IF-2B PF01008.17 CUU97870.1 - 0.044 13.0 0.0 0.056 12.7 0.0 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family SPT_ssu-like PF11779.8 CUU97872.1 - 0.36 10.5 4.0 0.4 10.3 3.2 1.6 1 1 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like SidC_N PF18219.1 CUU97873.1 - 0.039 12.9 0.1 0.047 12.7 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain RNase_PH PF01138.21 CUU97874.1 - 3.6e-48 163.4 0.5 3.8e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CUU97874.1 - 8e-08 32.2 0.1 2.2e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HET-s_218-289 PF11558.8 CUU97874.1 - 0.066 13.3 0.1 21 5.2 0.0 2.7 2 0 0 2 2 2 0 Het-s 218-289 DUF974 PF06159.13 CUU97877.1 - 7.3e-20 71.8 0.0 1.2e-19 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun-like PF12742.7 CUU97877.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC9-Trs120 PF08626.11 CUU97877.1 - 0.0036 14.7 0.0 0.0046 14.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ARL2_Bind_BART PF11527.8 CUU97878.1 - 4.9e-10 39.5 6.1 5.3e-10 39.4 6.1 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART LRR_4 PF12799.7 CUU97879.1 - 1.3e-13 50.9 13.5 0.00022 21.5 0.2 5.0 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CUU97879.1 - 3e-09 36.6 2.0 7.3e-07 28.8 0.7 2.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 CUU97879.1 - 1.2e-08 34.6 13.3 0.00095 18.9 0.2 4.5 3 2 2 5 5 5 3 Leucine rich repeat LRR_6 PF13516.6 CUU97879.1 - 5.6e-06 26.0 7.5 2.1 8.6 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CUU97879.1 - 1.4e-05 25.0 8.8 23 6.0 0.0 6.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4637 PF15470.6 CUU97879.1 - 0.00079 19.2 2.0 0.00079 19.2 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4637) GNAT_acetyltr_2 PF13718.6 CUU97879.1 - 6.9 6.0 8.2 0.3 10.5 0.8 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 GEMIN8 PF15348.6 CUU97879.1 - 7.7 6.8 12.8 0.4 10.9 4.0 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 zf-LITAF-like PF10601.9 CUU97880.1 - 1.1e-08 35.3 0.9 1.7e-08 34.6 0.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain C2 PF00168.30 CUU97881.1 - 1.3e-16 60.7 0.0 8.3e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain Herpes_gE PF02480.16 CUU97881.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E C2 PF00168.30 CUU97882.1 - 1e-16 61.1 0.0 8.5e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain Herpes_gE PF02480.16 CUU97882.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TetR_C_8 PF14278.6 CUU97883.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Swm2 PF17083.5 CUU97885.1 - 0.074 13.1 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Nckap1 PF09735.9 CUU97887.1 - 7.9e-261 868.6 0.0 2.6e-230 767.5 0.0 3.0 2 1 0 2 2 2 2 Membrane-associated apoptosis protein Nckap1 PF09735.9 CUU97888.1 - 9.3e-13 47.1 0.1 5.4e-12 44.6 0.1 1.9 1 1 0 1 1 1 1 Membrane-associated apoptosis protein DUF3888 PF13027.6 CUU97888.1 - 1.9 9.0 4.3 1e+02 3.4 0.3 3.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3888) PNP_UDP_1 PF01048.20 CUU97889.1 - 2.3e-16 59.8 0.3 2.5e-16 59.7 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2207 PF09972.9 CUU97894.1 - 0.00036 19.4 0.5 0.00065 18.6 0.5 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Rax2 PF12768.7 CUU97894.1 - 0.015 14.7 0.2 0.029 13.8 0.2 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RIF5_SNase_2 PF18189.1 CUU97895.1 - 0.044 13.6 0.3 0.064 13.1 0.3 1.2 1 0 0 1 1 1 0 TbRIF5 SNase domain 2 PDZ_6 PF17820.1 CUU97897.1 - 1.6e-12 47.1 0.0 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CUU97897.1 - 7.3e-12 45.5 0.1 2.4e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CUU97897.1 - 3.4e-07 30.5 0.1 1.6e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 PDZ domain DDE_3 PF13358.6 CUU97898.1 - 0.002 17.9 0.4 0.0022 17.8 0.4 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_S21e PF01249.18 CUU97899.1 - 0.015 15.4 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S21e Band_7 PF01145.25 CUU97904.1 - 7.9e-27 94.4 3.3 1.1e-26 94.0 3.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CUU97904.1 - 0.026 14.3 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Peptidase_S66 PF02016.15 CUU97904.1 - 0.047 13.8 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain EutA PF06277.11 CUU97904.1 - 0.16 10.8 1.8 1.5 7.6 1.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA La PF05383.17 CUU97906.1 - 3.7e-07 30.1 0.0 8.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 La domain GTP_CH_N PF12471.8 CUU97907.1 - 0.063 13.0 0.0 0.071 12.9 0.0 1.3 1 1 0 1 1 1 0 GTP cyclohydrolase N terminal PARP PF00644.20 CUU97908.1 - 0.00034 20.3 0.1 0.42 10.2 0.0 2.0 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Beach PF02138.18 CUU97909.1 - 0.028 13.8 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 Beige/BEACH domain zinc_ribbon_10 PF10058.9 CUU97912.1 - 0.099 12.4 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PyrI_C PF02748.15 CUU97912.1 - 2.1 8.3 6.5 0.47 10.4 1.7 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CD34_antigen PF06365.12 CUU97913.1 - 0.14 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family CRM1_C PF08767.11 CUU97914.1 - 3e-34 118.7 0.9 3.4e-34 118.4 0.9 1.0 1 0 0 1 1 1 1 CRM1 C terminal CRM1_C PF08767.11 CUU97915.1 - 8.8e-14 51.4 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 CRM1 C terminal MitMem_reg PF13012.6 CUU97915.1 - 3.2e-12 46.9 1.4 2e-11 44.3 1.1 2.5 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CUU97915.1 - 5.3e-09 36.1 0.9 1.3e-08 34.8 0.2 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Calpain_III PF01067.22 CUU97916.1 - 2.8e-14 53.6 1.6 7.4e-06 26.3 0.1 2.9 2 1 0 2 2 2 2 Calpain large subunit, domain III LOH1CR12 PF10158.9 CUU97917.1 - 3.8e-05 23.7 0.1 0.17 11.9 0.0 2.4 2 0 0 2 2 2 2 Tumour suppressor protein LEA_3 PF03242.13 CUU97917.1 - 0.00052 20.7 0.4 2.3 9.0 0.1 2.6 2 0 0 2 2 2 2 Late embryogenesis abundant protein DUF1491 PF07372.12 CUU97917.1 - 0.0013 19.1 0.1 3.9 7.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1491) DUF2075 PF09848.9 CUU97917.1 - 0.0032 16.7 0.7 2 7.6 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) DUF503 PF04456.12 CUU97917.1 - 0.0035 17.2 0.1 5.5 6.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF503) AHD PF17793.1 CUU97917.1 - 0.045 13.6 0.2 16 5.4 0.0 2.6 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Forkhead PF00250.18 CUU97918.1 - 2.6e-32 110.9 0.2 5.5e-32 109.9 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain Fez1 PF06818.15 CUU97919.1 - 0.037 14.5 39.2 0.67 10.4 8.5 3.0 1 1 2 3 3 3 0 Fez1 Gp37 PF09646.10 CUU97919.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Gp37 protein Streptin-Immun PF11083.8 CUU97919.1 - 1 9.8 8.5 0.21 12.0 1.5 2.9 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein DUF4407 PF14362.6 CUU97919.1 - 1.1 8.5 29.5 1.4 8.2 5.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4776 PF16003.5 CUU97919.1 - 3 6.7 10.5 4.5 6.1 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SlyX PF04102.12 CUU97919.1 - 3.3 8.4 26.7 6.8 7.4 2.2 6.1 5 2 0 5 5 5 0 SlyX DUF1844 PF08899.11 CUU97919.1 - 6.4 7.1 8.4 0.35 11.2 1.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) Filament PF00038.21 CUU97919.1 - 8.5 5.9 38.6 18 4.8 4.8 4.4 2 1 2 4 4 4 0 Intermediate filament protein cwf18 PF08315.12 CUU97920.1 - 8.4e-32 110.7 2.3 1.4e-31 109.9 2.3 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF89 PF01937.19 CUU97921.1 - 1e-53 182.6 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF89 PF01937.19 CUU97922.1 - 0.00021 20.4 0.0 0.00023 20.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Nro1 PF12753.7 CUU97922.1 - 0.04 12.9 0.1 0.04 12.9 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Peptidase_C3G PF12381.8 CUU97922.1 - 0.19 11.2 0.0 0.23 10.9 0.0 1.0 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase Vps5 PF09325.10 CUU97923.1 - 4.3e-60 203.2 14.8 1.8e-44 152.1 6.4 4.1 3 1 0 4 4 4 2 Vps5 C terminal like TACC_C PF05010.14 CUU97923.1 - 5.4e-28 98.2 23.7 5.4e-28 98.2 23.7 2.4 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Macoilin PF09726.9 CUU97923.1 - 0.0004 19.1 8.1 0.0004 19.1 8.1 2.0 2 0 0 2 2 2 1 Macoilin family PX PF00787.24 CUU97923.1 - 0.0047 16.9 0.2 0.093 12.7 0.1 2.8 2 0 0 2 2 2 1 PX domain DUF4992 PF16383.5 CUU97923.1 - 0.051 13.1 0.2 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function TPR_12 PF13424.6 CUU97923.1 - 0.12 12.7 9.0 3 8.2 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5082 PF16888.5 CUU97923.1 - 0.16 12.3 23.4 0.03 14.6 17.9 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) LMBR1 PF04791.16 CUU97923.1 - 0.66 8.8 7.9 0.2 10.5 4.9 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein Caskin-Pro-rich PF16907.5 CUU97923.1 - 1.3 9.6 20.8 0.29 11.7 1.0 3.8 4 0 0 4 4 4 0 Proline rich region of Caskin proteins Bac_GDH PF05088.12 CUU97923.1 - 2 5.8 17.3 0.23 8.9 0.7 2.1 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase ADIP PF11559.8 CUU97923.1 - 3.3 7.8 29.7 0.45 10.6 16.5 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1835 PF08874.10 CUU97923.1 - 3.5 7.8 6.8 47 4.2 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1835) G-patch_2 PF12656.7 CUU97924.1 - 9.6e-15 54.4 0.0 2.2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 CUU97924.1 - 6.3e-07 29.1 8.8 0.00038 20.3 0.1 3.2 3 0 0 3 3 3 2 KOW motif Glyco_transf_7N PF13733.6 CUU97925.1 - 1.4e-18 66.8 0.1 5.8e-18 64.8 0.1 1.9 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 PUA PF01472.20 CUU97925.1 - 2.6e-18 65.7 0.1 5e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 CUU97925.1 - 3.6e-17 62.8 0.2 7.5e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Pre-PUA-like domain Glyco_transf_7C PF02709.14 CUU97925.1 - 5.4e-09 35.6 2.1 1.6e-08 34.1 1.9 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase KOW PF00467.29 CUU97925.1 - 0.00024 20.9 0.1 0.00046 20.0 0.1 1.5 1 0 0 1 1 1 1 KOW motif Glyco_transf_7C PF02709.14 CUU97926.1 - 6.6e-19 67.4 0.2 1.5e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Pre-PUA PF17832.1 CUU97926.1 - 3e-17 63.1 0.2 5.8e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CUU97926.1 - 4.7e-15 55.3 0.0 8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 PUA domain Glyco_transf_7N PF13733.6 CUU97926.1 - 0.00038 20.1 0.0 0.0018 17.9 0.0 2.1 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 CUU97926.1 - 0.04 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Homeobox_KN PF05920.11 CUU97927.1 - 9.3e-19 67.1 1.6 1.4e-17 63.3 1.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CUU97927.1 - 1.8e-08 34.1 0.1 3.9e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Exo5 PF09810.9 CUU97928.1 - 0.018 14.6 0.2 0.021 14.3 0.2 1.0 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DEK_C PF08766.11 CUU97928.1 - 0.035 14.0 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 DEK C terminal domain Orf78 PF06024.12 CUU97928.1 - 0.075 13.3 0.2 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Exo5 PF09810.9 CUU97929.1 - 0.018 14.6 0.2 0.021 14.3 0.2 1.0 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DEK_C PF08766.11 CUU97929.1 - 0.035 14.0 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 DEK C terminal domain Orf78 PF06024.12 CUU97929.1 - 0.075 13.3 0.2 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Orf78 (ac78) PC4 PF02229.16 CUU97930.1 - 0.017 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) zinc_ribbon_10 PF10058.9 CUU97932.1 - 8.9e-11 41.4 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF1773 PF08593.10 CUU97932.1 - 0.093 13.8 0.7 0.18 12.8 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function PPP1R35_C PF15503.6 CUU97933.1 - 6.7e-16 58.4 1.0 1e-15 57.8 1.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus zf-RVT PF13966.6 CUU97935.1 - 0.0025 18.5 0.7 0.003 18.3 0.7 1.3 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase STAR_dimer PF16544.5 CUU97936.1 - 2e-18 65.7 1.0 6.5e-18 64.0 1.0 1.9 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CUU97936.1 - 0.00016 21.4 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 KH domain F-box-like PF12937.7 CUU97937.1 - 7.3e-14 51.4 1.7 7.3e-14 51.4 1.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CUU97937.1 - 9e-13 47.8 2.2 2.3e-12 46.5 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CUU97937.1 - 0.013 15.4 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 CUU97938.1 - 7.3e-14 51.4 1.7 7.3e-14 51.4 1.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CUU97938.1 - 9e-13 47.8 2.2 2.3e-12 46.5 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CUU97938.1 - 0.013 15.4 0.1 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 F-box ESCRT-II PF05871.12 CUU97939.1 - 3.7e-48 163.3 1.1 1.5e-47 161.4 0.4 2.2 3 0 0 3 3 3 1 ESCRT-II complex subunit BPL_LplA_LipB PF03099.19 CUU97940.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family UQ_con PF00179.26 CUU97941.1 - 2.1e-49 166.8 0.0 2.3e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CUU97941.1 - 0.0029 17.3 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CUU97941.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Mito_carr PF00153.27 CUU97942.1 - 0.033 14.1 0.2 0.1 12.5 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial carrier protein PUA PF01472.20 CUU97943.1 - 8e-19 67.4 0.1 1.3e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 CUU97943.1 - 1.1e-17 64.5 0.2 1.9e-17 63.7 0.2 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain EF-hand_7 PF13499.6 CUU97944.1 - 1.2e-19 70.5 12.7 2.2e-13 50.4 6.6 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CUU97944.1 - 2e-17 61.3 11.5 6e-08 31.7 2.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CUU97944.1 - 1.8e-14 52.4 9.2 3.3e-05 23.5 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CUU97944.1 - 8.7e-11 41.5 4.0 8.7e-11 41.5 4.0 2.9 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 CUU97944.1 - 1.2e-07 31.9 0.3 4.8e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CUU97944.1 - 6.8e-06 25.3 9.0 0.0051 16.2 1.7 3.4 3 0 0 3 3 3 2 EF hand Acetyltransf_1 PF00583.25 CUU97946.1 - 1.1e-09 38.5 0.1 4.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CUU97946.1 - 1.5e-05 25.3 4.0 0.00011 22.5 1.1 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CUU97946.1 - 3.1e-05 23.9 0.2 0.0096 15.9 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Vma12 PF11712.8 CUU97947.1 - 6.9e-18 65.1 0.1 1e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3087 PF11286.8 CUU97947.1 - 0.022 14.2 0.7 0.036 13.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) NDUF_B7 PF05676.13 CUU97948.1 - 2.6e-23 81.5 1.5 2.6e-23 81.5 1.5 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CUU97948.1 - 0.064 13.3 2.0 0.11 12.5 2.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Vault PF01505.18 CUU97949.1 - 8.5e-57 189.1 0.0 3.4e-15 55.9 0.0 5.2 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 CUU97949.1 - 1.6e-52 176.6 0.1 2.8e-52 175.7 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CUU97949.1 - 2.2e-35 120.5 0.4 4.5e-29 100.3 0.0 3.5 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_2 PF17794.1 CUU97949.1 - 1.4e-33 115.0 0.3 6.9e-22 77.6 0.1 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CUU97949.1 - 9.7e-33 112.1 0.1 1.9e-31 107.9 0.1 3.0 3 0 0 3 3 3 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CUU97949.1 - 0.00041 20.4 0.0 17 5.6 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3601) DUF2543 PF10820.8 CUU97949.1 - 1.8 8.8 5.3 0.55 10.5 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2543) Vault_2 PF17794.1 CUU97950.1 - 2.2e-23 82.4 0.1 3.6e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Major Vault Protein repeat domain Vault_3 PF17795.1 CUU97950.1 - 0.0028 17.7 0.1 0.0045 17.0 0.1 1.4 1 0 0 1 1 1 1 Major Vault Protein Repeat domain Vma12 PF11712.8 CUU97952.1 - 6.9e-18 65.1 0.1 1e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3087 PF11286.8 CUU97952.1 - 0.022 14.2 0.7 0.036 13.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) MFS_MOT1 PF16983.5 CUU97958.1 - 0.011 16.1 1.2 0.019 15.4 1.2 1.3 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily Tetraspanin PF00335.20 CUU97958.1 - 0.75 9.5 12.2 1.2 8.8 12.2 1.4 1 1 0 1 1 1 0 Tetraspanin family I-set PF07679.16 CUU97959.1 - 9e-08 32.1 0.0 4.5 7.4 0.0 5.0 5 0 0 5 5 5 4 Immunoglobulin I-set domain DUF4962 PF16332.5 CUU97959.1 - 0.0031 16.1 0.0 1.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4962) PaRep2b PF07775.11 CUU97959.1 - 0.005 15.4 0.0 0.011 14.3 0.0 1.4 2 0 0 2 2 2 1 PaRep2b protein PARP PF00644.20 CUU97960.1 - 8e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CUU97960.1 - 4.4e-07 30.1 0.1 6e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BAR PF03114.18 CUU97960.1 - 0.07 12.8 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 BAR domain GDI PF00996.18 CUU97960.1 - 0.088 11.3 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor PARP PF00644.20 CUU97961.1 - 1e-17 64.3 0.1 3.2e-10 39.9 0.0 2.8 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CUU97961.1 - 2.1e-06 27.9 0.1 3.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain CRA PF06589.11 CUU97961.1 - 0.025 14.7 0.5 0.067 13.3 0.1 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Phosphodiest PF01663.22 CUU97963.1 - 4.1e-57 194.4 0.2 4.9e-57 194.1 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CUU97963.1 - 0.00028 20.4 0.0 0.87 8.9 0.0 2.7 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 CUU97963.1 - 0.0013 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 CUU97963.1 - 0.0088 16.1 0.0 0.044 13.9 0.0 1.9 2 0 0 2 2 2 1 PglZ domain Nucleopor_Nup85 PF07575.13 CUU97964.1 - 5.4e-37 127.6 3.0 1.5e-35 122.8 3.0 2.1 1 1 0 1 1 1 1 Nup85 Nucleoporin RNA_pol_L PF01193.24 CUU97965.1 - 1.3e-19 69.4 0.0 3.5e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CUU97965.1 - 1.6e-17 63.9 0.0 2.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 CUU97965.1 - 7.6e-07 28.8 0.0 0.00036 20.3 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 CUU97965.1 - 0.18 11.5 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 Nucleopor_Nup85 PF07575.13 CUU97966.1 - 2.9e-23 82.3 4.1 3.3e-23 82.1 4.1 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin HTH_15 PF12324.8 CUU97966.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase RNA_pol_L PF01193.24 CUU97967.1 - 3e-22 77.8 0.0 3.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 CUU97967.1 - 1.5e-21 75.9 0.0 6e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 CUU97967.1 - 1.6e-17 63.9 0.0 3.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain DUF22 PF01629.16 CUU97967.1 - 0.19 11.4 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 CEP44 PF15007.6 CUU97968.1 - 3.1e-31 108.2 0.3 6.2e-31 107.2 0.3 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 MitMem_reg PF13012.6 CUU97968.1 - 0.017 15.5 2.2 0.1 13.0 0.3 2.5 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Pol_alpha_B_N PF08418.10 CUU97968.1 - 0.14 12.1 4.4 0.2 11.6 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FlaC_arch PF05377.11 CUU97968.1 - 0.24 11.8 3.1 0.29 11.5 0.5 2.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CUU97968.1 - 1 9.4 3.0 2.9 7.9 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 CUU97969.1 - 0.0026 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YniB PF14002.6 CUU97975.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 YniB-like protein TFIIF_alpha PF05793.12 CUU97975.1 - 0.07 11.7 3.7 0.084 11.5 3.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EF-hand_1 PF00036.32 CUU97978.1 - 5.8e-21 72.4 4.3 9.2e-06 24.9 0.0 5.1 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CUU97978.1 - 6.7e-21 72.4 0.9 1.3e-06 27.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CUU97978.1 - 5.9e-19 68.3 0.6 5.7e-08 33.1 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU97978.1 - 7.1e-18 63.2 1.8 5.4e-06 25.7 0.0 3.6 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CUU97978.1 - 1.8e-11 43.7 2.4 0.00023 21.0 0.0 4.6 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CUU97978.1 - 0.0065 16.8 0.0 6.2 7.2 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain DUF2201 PF09967.9 CUU97978.1 - 0.016 15.3 0.3 3.9 7.6 0.0 2.6 2 1 0 2 2 2 0 VWA-like domain (DUF2201) UMP1 PF05348.11 CUU97979.1 - 2.6e-13 50.2 0.1 7.7e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 bZIP_2 PF07716.15 CUU97979.1 - 4.3e-09 36.3 9.5 1e-08 35.1 9.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CUU97979.1 - 1.4e-08 34.7 6.9 2.7e-08 33.8 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4618 PF15397.6 CUU97979.1 - 0.0026 17.2 0.4 0.0041 16.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_Maf PF03131.17 CUU97979.1 - 0.018 15.5 5.9 0.039 14.5 5.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor MIF4G_like_2 PF09090.11 CUU97979.1 - 0.029 13.9 0.4 0.044 13.3 0.4 1.2 1 0 0 1 1 1 0 MIF4G like HALZ PF02183.18 CUU97979.1 - 0.068 13.4 2.4 0.14 12.4 2.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cadherin PF00028.17 CUU97980.1 - 1.4e-40 137.6 0.7 6.2e-16 58.6 0.0 5.5 5 0 0 5 5 5 5 Cadherin domain Cadherin_2 PF08266.12 CUU97980.1 - 0.00014 21.6 0.0 0.91 9.4 0.0 3.3 3 0 0 3 3 3 2 Cadherin-like Cadherin_4 PF17803.1 CUU97980.1 - 4.8 7.9 9.4 2.1 9.0 0.1 3.7 3 1 0 3 3 3 0 Bacterial cadherin-like domain Cadherin PF00028.17 CUU97981.1 - 8.4e-37 125.5 0.0 8.9e-16 58.1 0.0 3.3 3 0 0 3 3 3 3 Cadherin domain Cadherin_2 PF08266.12 CUU97981.1 - 1.7e-06 27.8 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 Cadherin-like TRP_2 PF08344.11 CUU97985.1 - 5.6e-29 100.1 0.5 1.4e-28 98.9 0.5 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CUU97985.1 - 1.2e-10 41.8 0.0 6.6e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CUU97985.1 - 2.3e-07 30.5 0.1 0.059 14.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CUU97985.1 - 5.2e-07 30.1 0.1 0.0023 18.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CUU97985.1 - 0.0049 17.3 0.0 6.4 7.4 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CUU97985.1 - 0.021 15.2 0.1 0.84 10.0 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DUF4346 PF14251.6 CUU97988.1 - 0.044 13.8 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) Clathrin_lg_ch PF01086.17 CUU97988.1 - 2.3 8.2 7.8 2 8.4 0.4 3.2 3 0 0 3 3 3 0 Clathrin light chain CNH PF00780.22 CUU97990.1 - 1.9e-29 103.1 0.0 2.2e-10 40.6 0.0 3.1 3 0 0 3 3 3 3 CNH domain Herpes_U47 PF05467.11 CUU97990.1 - 0.19 9.8 10.3 0.63 8.1 1.1 2.1 2 0 0 2 2 2 0 Herpesvirus glycoprotein U47 Corona_I PF03187.14 CUU97993.1 - 2e-13 50.5 0.0 0.75 9.4 0.0 6.8 6 1 1 7 7 7 6 Corona nucleocapsid I protein TetR_C_33 PF13305.6 CUU97993.1 - 8.7e-05 23.2 26.8 0.07 13.9 2.7 5.6 5 2 0 5 5 5 4 Tetracyclin repressor-like, C-terminal domain Claudin_2 PF13903.6 CUU97994.1 - 0.036 13.8 1.3 0.039 13.7 1.3 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Orai-1 PF07856.12 CUU97994.1 - 0.1 12.3 3.1 0.073 12.7 2.2 1.3 1 1 0 1 1 1 0 Mediator of CRAC channel activity Orf78 PF06024.12 CUU97994.1 - 0.75 10.1 4.2 0.39 11.0 2.5 1.4 1 1 0 1 1 1 0 Orf78 (ac78) GLTP PF08718.11 CUU97997.1 - 3.4e-22 79.3 0.0 4.8e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF974 PF06159.13 CUU98001.1 - 4.3e-18 66.0 0.0 5.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) RF-1 PF00472.20 CUU98003.1 - 5.3e-48 161.8 4.1 3.8e-23 81.6 0.3 2.2 2 0 0 2 2 2 2 RF-1 domain DUF2459 PF09601.10 CUU98003.1 - 0.029 14.2 0.2 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Cyclase_polyket PF04673.12 CUU98003.1 - 0.24 11.6 2.4 17 5.8 0.2 2.2 2 0 0 2 2 2 0 Polyketide synthesis cyclase Peptidase_M3_N PF08439.10 CUU98003.1 - 0.37 11.1 12.4 0.7 10.2 2.1 2.5 2 0 0 2 2 2 0 Oligopeptidase F Trehalase PF01204.18 CUU98003.1 - 0.51 9.1 6.7 3.3 6.4 0.9 2.0 2 0 0 2 2 2 0 Trehalase DUF3337 PF11816.8 CUU98003.1 - 0.71 9.7 7.2 5.2 6.9 0.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3337) SHR3_chaperone PF08229.11 CUU98003.1 - 6.6 5.7 4.9 28 3.6 0.4 2.3 2 0 0 2 2 2 0 ER membrane protein SH3 zf_UBZ PF18439.1 CUU98006.1 - 0.041 13.5 1.9 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rep_fac-A_C PF08646.10 CUU98006.1 - 5.6 6.7 10.8 8.3 6.1 1.3 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain GAS PF13851.6 CUU98007.1 - 0.0083 15.5 1.6 0.54 9.6 0.0 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Halo_GVPC PF05465.13 CUU98007.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Baculo_PEP_C PF04513.12 CUU98007.1 - 0.18 11.9 1.6 12 5.9 0.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_C PF15908.5 CUU98007.1 - 0.26 11.6 2.7 6.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Deltameth_res PF16020.5 CUU98008.1 - 4.3e-17 61.7 0.1 5.9e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Deltamethrin resistance UPF0113 PF03657.13 CUU98009.1 - 3.1e-21 75.4 0.0 5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 CUU98009.1 - 4.1e-21 75.3 0.3 6.3e-21 74.7 0.3 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 CUU98009.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 PUA domain DC_STAMP PF07782.13 CUU98012.1 - 8.2e-23 81.2 0.1 3.2e-20 72.8 0.0 2.9 2 1 0 2 2 2 1 DC-STAMP-like protein Bunya_RdRp PF04196.12 CUU98014.1 - 0.19 10.1 0.4 0.22 9.9 0.4 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase PH PF00169.29 CUU98016.1 - 1.4e-06 28.7 0.0 5.7e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CUU98016.1 - 0.0026 18.1 0.1 0.0074 16.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CUU98016.1 - 0.007 16.8 0.1 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PNP_UDP_1 PF01048.20 CUU98017.1 - 0.0002 20.7 0.2 0.0016 17.7 0.8 1.9 2 0 0 2 2 2 1 Phosphorylase superfamily CAP PF00188.26 CUU98018.1 - 1.3e-15 58.4 1.7 5e-15 56.4 1.7 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family 7tm_1 PF00001.21 CUU98023.1 - 6.6e-14 51.9 0.1 1e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CUU98023.1 - 0.0038 16.6 1.0 0.0057 16.1 1.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.6 CUU98023.1 - 0.0099 15.6 1.3 0.013 15.3 1.3 1.1 1 0 0 1 1 1 1 Olfactory receptor DUF2207 PF09972.9 CUU98023.1 - 0.053 12.3 0.3 0.058 12.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.12 CUU98023.1 - 0.15 12.0 2.3 0.24 11.4 2.3 1.3 1 0 0 1 1 1 0 Ninjurin AC_N PF16214.5 CUU98023.1 - 0.34 10.0 1.7 0.42 9.7 1.7 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Rad51 PF08423.11 CUU98024.1 - 1.2e-18 67.3 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Rad51 DNA_processg_A PF02481.15 CUU98024.1 - 0.081 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A tify PF06200.14 CUU98025.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain CK_II_beta PF01214.18 CUU98026.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Peptidase_M99_m PF17130.4 CUU98027.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 Suf PF05843.14 CUU98028.1 - 3.5e-70 237.3 4.0 3.2e-66 224.3 0.0 5.0 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) SF3A3 PF16837.5 CUU98028.1 - 0.0016 18.9 1.1 0.38 11.3 0.0 3.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TPR_14 PF13428.6 CUU98028.1 - 0.0049 17.6 4.7 3.5 8.7 0.0 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 CUU98028.1 - 0.021 14.2 0.2 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP NRDE-2 PF08424.10 CUU98028.1 - 0.21 10.7 13.4 7.3 5.6 1.7 4.9 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 CUU98028.1 - 2 8.8 8.8 3.9 7.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FEZ PF07763.13 CUU98029.1 - 2.3e-06 27.5 1.1 4.3e-06 26.7 1.1 1.4 1 0 0 1 1 1 1 FEZ-like protein HTH_ABP1_N PF18107.1 CUU98030.1 - 0.0075 16.0 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 2 Fission yeast centromere protein N-terminal domain Osmo_CC PF08946.10 CUU98030.1 - 0.038 14.3 0.1 13 6.1 0.0 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil zf-C2H2_9 PF16293.5 CUU98030.1 - 0.31 10.9 1.1 18 5.3 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Ank_2 PF12796.7 CUU98032.1 - 4.4e-32 110.5 0.0 4.4e-12 46.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU98032.1 - 7.2e-18 64.7 0.0 1.1e-05 25.8 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU98032.1 - 1.1e-17 62.3 2.5 0.0074 16.7 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 CUU98032.1 - 1.6e-16 60.1 0.9 2.2e-06 27.8 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CUU98032.1 - 1.8e-16 59.7 7.7 0.00048 20.5 0.1 5.8 6 1 0 6 6 6 4 Ankyrin repeat LRR_8 PF13855.6 CUU98034.1 - 1.3e-16 60.0 7.0 1.3e-06 28.1 0.6 3.7 1 1 1 3 3 3 3 Leucine rich repeat I-set PF07679.16 CUU98034.1 - 4.3e-09 36.3 0.3 2.5e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CUU98034.1 - 5.2e-09 36.6 1.1 1.4e-07 32.0 0.0 3.0 2 0 0 2 2 2 1 Immunoglobulin domain LRR_4 PF12799.7 CUU98034.1 - 7.4e-08 32.6 8.0 0.006 17.0 2.9 4.1 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CUU98034.1 - 4.2e-07 29.6 14.4 0.19 12.4 0.3 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat Ig_2 PF13895.6 CUU98034.1 - 1.4e-06 28.5 0.2 6.6e-06 26.4 0.2 2.2 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CUU98034.1 - 0.00016 21.8 0.1 0.0007 19.7 0.1 2.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CUU98034.1 - 0.00096 19.3 0.1 0.026 14.7 0.1 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_6 PF13516.6 CUU98034.1 - 0.033 14.3 3.8 11 6.4 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich repeat Insulin_TMD PF17870.1 CUU98034.1 - 0.033 14.3 0.2 0.085 12.9 0.2 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Exo_endo_phos PF03372.23 CUU98035.1 - 4.7e-19 68.8 0.1 3.4e-18 66.0 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_capsid PF06112.11 CUU98035.1 - 3.8 7.6 11.2 6.2 6.9 11.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribosomal_L34e PF01199.18 CUU98036.1 - 0.0034 17.7 0.1 4.7 7.6 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein L34e Corona_NS8 PF12093.8 CUU98036.1 - 0.0034 17.9 0.4 3.5 8.2 0.1 2.3 2 0 0 2 2 2 2 Coronavirus NS8 protein DUF1133 PF06576.11 CUU98036.1 - 0.018 14.4 3.0 2.4 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) FGase PF05013.12 CUU98036.1 - 0.027 14.7 0.2 9.8 6.3 0.0 2.3 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase ApoA-II PF04711.13 CUU98036.1 - 0.067 13.4 0.0 26 5.1 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) TetR_C_20 PF17925.1 CUU98036.1 - 0.16 12.3 0.0 30 5.0 0.0 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IncFII_repA PF02387.15 CUU98036.1 - 0.3 10.3 1.6 1.9 7.7 0.5 2.0 2 0 0 2 2 2 0 IncFII RepA protein family DUF761 PF05553.11 CUU98036.1 - 1.8 8.2 9.2 4.8 6.8 0.3 2.8 3 0 0 3 3 3 0 Cotton fibre expressed protein Mon2_C PF16206.5 CUU98038.1 - 1.2e-22 79.9 0.1 1.7e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Mon2_C PF16206.5 CUU98039.1 - 1.1e-35 123.0 0.1 1.4e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein K_channel_TID PF07941.11 CUU98039.1 - 0.3 11.6 3.9 0.48 10.9 3.9 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain eIF3_subunit PF08597.10 CUU98040.1 - 1.3e-56 192.3 46.9 3.3e-28 99.2 19.0 2.0 1 1 0 2 2 2 2 Translation initiation factor eIF3 subunit DUF4634 PF15465.6 CUU98040.1 - 0.00035 20.9 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4634) TMEM206 PF15122.6 CUU98040.1 - 0.005 16.0 4.0 1 8.5 0.3 2.3 2 0 0 2 2 2 2 TMEM206 protein family Hypoth_Ymh PF09509.10 CUU98040.1 - 0.0064 16.4 0.6 4.4 7.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (Hypoth_ymh) DUF1204 PF06721.11 CUU98040.1 - 0.0071 15.8 18.4 0.31 10.5 5.3 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1204) DUF5605 PF18310.1 CUU98040.1 - 0.12 12.2 1.0 18 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) HXXSHH PF07586.11 CUU98040.1 - 0.27 10.8 12.1 2.2 7.8 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) DUF1992 PF09350.10 CUU98040.1 - 0.75 10.0 17.5 2.2 8.5 1.9 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1992) DUF932 PF06067.11 CUU98040.1 - 0.81 9.4 6.6 8.5 6.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) TonB_N PF16031.5 CUU98040.1 - 2.9 8.4 20.4 7.1 7.1 5.9 2.7 2 0 0 2 2 2 0 TonB polyproline region EVC2_like PF12297.8 CUU98040.1 - 5.5 5.6 18.8 1.5 7.4 4.2 2.3 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein VSG_B PF13206.6 CUU98040.1 - 8.9 5.5 11.7 6.4 5.9 1.9 2.2 2 0 0 2 2 2 0 Trypanosomal VSG domain Enolase_C PF00113.22 CUU98042.1 - 2.2e-152 506.4 0.2 3.7e-152 505.7 0.2 1.4 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CUU98042.1 - 6.6e-61 204.3 0.1 1.5e-60 203.1 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain TAF6_C PF07571.13 CUU98042.1 - 9e-15 54.8 0.0 3.1e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain MR_MLE_C PF13378.6 CUU98042.1 - 1.4e-07 31.4 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CUU98042.1 - 1.2e-05 24.6 1.2 3.1e-05 23.2 1.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus LST1 PF05083.13 CUU98043.1 - 1.3e-05 25.4 0.3 2.1e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 LST-1 protein Shisa PF13908.6 CUU98043.1 - 0.0032 17.8 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CUU98043.1 - 0.0074 17.1 0.0 0.01 16.7 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Comm PF15957.5 CUU98043.1 - 0.0099 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Commissureless WBP-1 PF11669.8 CUU98043.1 - 0.018 15.7 4.0 0.028 15.1 3.9 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 Sensor PF13796.6 CUU98043.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative sensor FAM176 PF14851.6 CUU98043.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Cadherin_C_2 PF16492.5 CUU98043.1 - 0.026 15.3 0.0 0.037 14.8 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MLANA PF14991.6 CUU98043.1 - 0.042 14.1 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A PhoR PF11808.8 CUU98043.1 - 0.042 14.3 0.0 0.059 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR TMEM132D_C PF15706.5 CUU98043.1 - 0.055 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Adeno_E3_CR2 PF02439.15 CUU98043.1 - 0.056 13.2 2.8 0.091 12.5 2.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tweety PF04906.13 CUU98043.1 - 0.057 12.1 0.4 0.076 11.7 0.4 1.1 1 0 0 1 1 1 0 Tweety PAG PF15347.6 CUU98043.1 - 0.057 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TMIE PF16038.5 CUU98043.1 - 0.058 13.2 0.4 0.094 12.6 0.4 1.3 1 0 0 1 1 1 0 TMIE protein Ctr PF04145.15 CUU98043.1 - 0.1 13.2 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Herpes_gE PF02480.16 CUU98043.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.11 CUU98043.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Mlo PF03094.15 CUU98043.1 - 0.12 10.7 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Mlo family PRIMA1 PF16101.5 CUU98043.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.5 2 0 0 2 2 1 0 Proline-rich membrane anchor 1 CYYR1 PF10873.8 CUU98043.1 - 0.26 11.7 3.5 0.35 11.3 3.5 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Rhabdo_glycop PF00974.18 CUU98043.1 - 0.42 9.0 3.3 0.35 9.2 2.2 1.3 1 1 0 1 1 1 0 Rhabdovirus spike glycoprotein RCR PF12273.8 CUU98043.1 - 1.6 9.4 5.6 1.3 9.7 2.9 1.8 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pkinase PF00069.25 CUU98045.1 - 0.00041 19.8 0.1 0.00067 19.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain MIT PF04212.18 CUU98045.1 - 0.0006 19.8 0.1 0.045 13.8 0.0 2.1 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Pyrid_oxidase_2 PF13883.6 CUU98047.1 - 0.0031 17.5 0.8 10 6.0 0.0 4.8 6 0 0 6 6 6 2 Pyridoxamine 5'-phosphate oxidase Bombinin PF05298.11 CUU98047.1 - 0.047 13.4 8.1 2.3 7.9 0.9 3.1 2 0 0 2 2 2 0 Bombinin DUF1409 PF07197.12 CUU98047.1 - 0.35 10.8 4.1 15 5.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) PRA1 PF03208.19 CUU98048.1 - 0.067 12.8 1.0 0.11 12.1 1.0 1.4 1 0 0 1 1 1 0 PRA1 family protein LsmAD PF06741.13 CUU98049.1 - 3e-15 56.5 0.3 6.9e-15 55.3 0.3 1.7 1 0 0 1 1 1 1 LsmAD domain EzrA PF06160.12 CUU98049.1 - 0.09 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IMS PF00817.20 CUU98050.1 - 2.2e-38 131.6 0.0 5.6e-38 130.3 0.0 1.6 1 1 0 1 1 1 1 impB/mucB/samB family RAP1 PF07218.11 CUU98050.1 - 3.5 5.8 4.3 5.6 5.1 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2_4 PF13894.6 CUU98051.1 - 0.0046 17.7 2.0 0.013 16.3 2.0 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CUU98051.1 - 0.011 16.1 2.0 0.023 15.1 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CUU98051.1 - 0.041 14.6 0.1 0.097 13.3 0.0 1.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CUU98051.1 - 0.053 13.3 3.3 0.12 12.2 3.3 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type Dynein_light PF01221.18 CUU98053.1 - 6.6e-15 55.2 0.2 9.7e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 TetR_C_37 PF18665.1 CUU98053.1 - 0.045 14.4 0.0 0.085 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Dynein_light PF01221.18 CUU98054.1 - 1.5e-41 140.6 0.0 4.1e-09 36.6 0.0 4.3 4 0 0 4 4 4 4 Dynein light chain type 1 EF-hand_1 PF00036.32 CUU98054.1 - 5.9e-07 28.6 0.0 4.7 7.0 0.0 5.0 5 0 0 5 5 5 3 EF hand Ground-like PF04155.18 CUU98054.1 - 8e-07 29.6 0.0 3.4 8.4 0.0 4.1 4 0 0 4 4 4 3 Ground-like domain EF-hand_7 PF13499.6 CUU98054.1 - 1.1e-06 29.0 0.0 0.93 10.0 0.0 6.2 5 2 0 5 5 5 1 EF-hand domain pair DUF3646 PF12362.8 CUU98054.1 - 1.5e-05 25.3 0.6 6.6 7.1 0.0 4.2 4 0 0 4 4 4 2 DNA polymerase III gamma and tau subunits C terminal EB1 PF03271.17 CUU98054.1 - 0.00024 21.3 1.4 1.1 9.6 0.1 2.9 2 0 0 2 2 2 2 EB1-like C-terminal motif FeoB_Cyto PF17910.1 CUU98054.1 - 0.0013 19.3 0.0 0.16 12.5 0.0 3.5 4 0 0 4 4 4 1 FeoB cytosolic helical domain EF-hand_6 PF13405.6 CUU98054.1 - 0.0014 18.4 0.0 39 4.5 0.1 4.9 5 0 0 5 5 5 0 EF-hand domain PRO8NT PF08082.11 CUU98054.1 - 0.0022 17.9 0.2 3.2 7.7 0.0 2.4 2 0 0 2 2 2 2 PRO8NT (NUC069), PrP8 N-terminal domain DUF5005 PF16396.5 CUU98054.1 - 0.0026 16.5 0.3 1.7 7.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5005) PPI_Ypi1 PF07491.11 CUU98054.1 - 0.0052 16.6 3.8 1.9 8.4 0.3 2.7 2 0 0 2 2 2 2 Protein phosphatase inhibitor EF-hand_8 PF13833.6 CUU98054.1 - 0.092 12.6 0.1 11 5.9 0.0 4.4 8 0 0 8 8 7 0 EF-hand domain pair MukB PF04310.12 CUU98054.1 - 0.13 12.1 0.0 86 2.8 0.0 3.5 4 0 0 4 4 4 0 MukB N-terminal Dynein_light PF01221.18 CUU98055.1 - 0.0001 22.5 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 SET PF00856.28 CUU98056.1 - 1.8e-07 31.7 0.2 3.2e-07 30.9 0.2 1.7 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 CUU98056.1 - 0.0015 18.5 2.6 0.66 10.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CUU98056.1 - 0.025 14.4 0.7 0.099 12.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP PF00188.26 CUU98057.1 - 1.3e-09 39.0 1.2 1.9e-09 38.4 1.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CUU98058.1 - 0.00032 21.5 0.4 0.00035 21.4 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Lipase_GDSL PF00657.22 CUU98058.1 - 0.11 12.4 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Proteasome PF00227.26 CUU98059.1 - 9.1e-61 204.7 0.4 1.2e-60 204.3 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CUU98059.1 - 1.4e-14 53.4 0.2 3e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FKBP_N PF01346.18 CUU98059.1 - 0.029 15.3 1.9 12 6.9 0.1 2.6 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Brix PF04427.18 CUU98060.1 - 1.1e-23 84.4 0.0 1.5e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Kunitz_BPTI PF00014.23 CUU98061.1 - 1.6e-17 63.4 0.1 2.3e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CUU98062.1 - 3.6e-17 62.3 1.3 4.3e-17 62.1 1.3 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Kunitz_BPTI PF00014.23 CUU98063.1 - 2.7e-08 33.9 4.5 3.5e-08 33.6 2.5 2.0 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain GED PF02212.18 CUU98064.1 - 5.7e-19 68.1 3.4 8.3e-19 67.5 3.4 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF816 PF05674.12 CUU98064.1 - 0.00081 19.4 0.9 0.0011 18.9 0.9 1.2 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) HECT PF00632.25 CUU98066.1 - 9.9e-67 225.6 0.0 3.4e-65 220.5 0.0 2.2 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RED_N PF07808.13 CUU98068.1 - 8.1e-80 267.8 10.8 8.1e-80 267.8 10.8 2.6 2 0 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 CUU98068.1 - 1.1e-48 164.4 6.3 2.5e-48 163.2 3.0 3.1 2 0 0 2 2 2 1 RED-like protein C-terminal region Lsm_interact PF05391.11 CUU98068.1 - 3.4e-07 29.5 0.2 1.6e-06 27.4 0.2 2.3 1 0 0 1 1 1 1 Lsm interaction motif Trypan_PARP PF05887.11 CUU98068.1 - 1.1 9.3 6.6 0.16 11.9 0.5 2.7 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) UQ_con PF00179.26 CUU98071.1 - 2.7e-35 121.1 0.1 3.1e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CUU98071.1 - 0.0013 18.5 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CUU98071.1 - 0.021 15.1 1.0 0.027 14.8 1.0 1.4 1 1 0 1 1 1 0 RWD domain MFS_1 PF07690.16 CUU98075.1 - 0.00018 20.6 1.9 0.0002 20.4 1.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 CUU98080.1 - 1.2e-05 25.5 9.9 0.0019 18.5 0.5 3.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU98080.1 - 0.0046 17.7 10.5 1.3 10.1 0.6 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CUU98080.1 - 0.0051 17.2 5.6 0.87 10.1 1.4 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CUU98080.1 - 0.056 13.8 3.3 0.81 10.1 0.1 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CUU98080.1 - 1.2 9.7 8.1 4.2 8.0 0.6 4.1 3 0 0 3 3 3 0 Zinc-finger double domain HTH_24 PF13412.6 CUU98081.1 - 0.061 12.9 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Kelch_1 PF01344.25 CUU98082.1 - 2.5e-35 119.8 10.8 1.5e-13 50.0 0.1 7.6 8 0 0 8 8 8 4 Kelch motif Kelch_4 PF13418.6 CUU98082.1 - 2.2e-25 88.4 0.6 1.2e-07 31.6 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CUU98082.1 - 2.2e-21 75.3 3.6 1.9e-06 28.0 0.0 7.1 8 0 0 8 8 8 2 Kelch motif BACK PF07707.15 CUU98082.1 - 1.7e-15 56.9 0.1 7e-05 22.9 0.0 4.2 2 2 2 4 4 4 2 BTB And C-terminal Kelch Kelch_3 PF13415.6 CUU98082.1 - 7e-15 54.9 10.4 0.00022 21.4 0.0 7.2 8 0 0 8 8 7 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CUU98082.1 - 1.6e-12 47.1 5.0 4.5e-05 23.3 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CUU98082.1 - 2e-12 46.6 0.1 0.00016 21.5 0.0 3.3 2 0 0 2 2 2 2 Kelch motif BTB PF00651.31 CUU98082.1 - 5.5e-08 33.0 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DIL PF01843.19 CUU98082.1 - 0.00067 19.9 0.9 1.8 8.9 0.1 2.6 2 0 0 2 2 2 2 DIL domain PQQ_3 PF13570.6 CUU98082.1 - 0.019 15.4 3.3 9.9 6.8 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain SRP-alpha_N PF04086.13 CUU98082.1 - 0.46 10.4 2.5 19 5.0 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal SOBP PF15279.6 CUU98083.1 - 0.021 15.4 2.2 0.028 15.1 2.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Fn3-like PF14310.6 CUU98087.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Fibronectin type III-like domain Arrestin_N PF00339.29 CUU98092.1 - 0.072 13.1 0.0 0.074 13.1 0.0 1.0 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PKS_DE PF18369.1 CUU98092.1 - 0.13 12.8 0.2 0.18 12.4 0.2 1.3 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain RT_RNaseH_2 PF17919.1 CUU98093.1 - 5.3e-11 42.4 2.1 1.9e-05 24.6 0.2 2.3 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CUU98093.1 - 6.7e-06 26.3 0.2 0.016 15.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Ntox25 PF15530.6 CUU98093.1 - 0.02 15.1 0.0 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 25 TarH PF02203.15 CUU98094.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.8 1 1 1 2 2 2 0 Tar ligand binding domain homologue ABC2_membrane_3 PF12698.7 CUU98096.1 - 0.00062 19.0 0.7 0.0007 18.8 0.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein CD20 PF04103.15 CUU98096.1 - 0.033 14.3 1.4 0.047 13.8 1.4 1.2 1 0 0 1 1 1 0 CD20-like family MitoNEET_N PF10660.9 CUU98096.1 - 0.1 12.7 0.3 0.23 11.5 0.0 1.8 2 1 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF3860 PF12976.7 CUU98097.1 - 0.019 15.0 0.0 6.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Epimerase_2 PF02350.19 CUU98097.1 - 0.1 11.4 0.1 9.3 5.0 0.0 2.0 1 1 1 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase ACC_epsilon PF13822.6 CUU98097.1 - 2.5 8.8 6.4 8.6 7.1 0.6 2.2 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit eIF_4G1 PF12152.8 CUU98098.1 - 0.017 15.3 1.7 7.8 6.8 0.1 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 Bac_RepA_C PF18008.1 CUU98098.1 - 1.2 9.6 8.9 13 6.2 1.2 3.2 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain DUF3492 PF11997.8 CUU98098.1 - 1.5 8.5 14.7 5.6 6.6 3.3 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3492) AKAP95 PF04988.12 CUU98099.1 - 0.016 15.4 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-H2C2_5 PF13909.6 CUU98099.1 - 0.057 13.2 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CUU98099.1 - 0.17 12.8 2.8 0.34 11.9 2.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CUU98100.1 - 8.9e-09 35.5 23.4 0.00016 22.2 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU98100.1 - 1.2e-06 28.7 18.6 9.8e-05 22.6 3.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CUU98100.1 - 0.00021 21.6 0.6 0.00021 21.6 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-4CXXC_R1 PF10497.9 CUU98100.1 - 0.037 14.2 11.9 0.061 13.6 11.9 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C2H2_jaz PF12171.8 CUU98100.1 - 0.05 13.9 15.7 1.2 9.6 3.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CUU98100.1 - 0.053 13.9 17.7 0.097 13.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CUU98100.1 - 0.39 11.0 13.1 0.43 10.9 5.0 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 CUU98100.1 - 1.5 9.1 14.7 1.5 9.0 0.3 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 CUU98100.1 - 5.2 7.5 13.8 19 5.6 4.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2703 PF10865.8 CUU98100.1 - 7.5 6.8 8.2 2.5 8.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Parvo_NS1 PF01057.17 CUU98103.1 - 2.2e-12 46.7 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CUU98103.1 - 1.5e-05 24.0 0.0 1.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase Torsin PF06309.11 CUU98103.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Torsin GyrB_insert PF18053.1 CUU98103.1 - 0.14 12.1 0.1 6.5 6.6 0.0 2.4 2 1 1 3 3 3 0 DNA gyrase B subunit insert domain Ig_6 PF18452.1 CUU98105.1 - 0.034 13.7 0.2 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain TPR_2 PF07719.17 CUU98107.1 - 1.6e-13 49.6 0.8 0.0004 20.3 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CUU98107.1 - 2.6e-08 33.4 0.0 0.0087 15.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CUU98107.1 - 4.3e-06 27.1 0.1 0.38 11.7 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CUU98107.1 - 1.1e-05 25.2 0.1 0.084 13.1 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CUU98107.1 - 0.00018 21.1 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CUU98107.1 - 0.00091 19.8 0.2 0.046 14.4 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CUU98107.1 - 0.003 17.7 0.0 1.7 8.8 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU98107.1 - 0.0031 18.0 0.8 0.016 15.7 0.0 2.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CUU98107.1 - 0.019 15.5 4.8 5.5 7.8 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat CedA PF10729.9 CUU98107.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Cell division activator CedA DUF5357 PF17310.2 CUU98107.1 - 0.18 10.4 2.9 0.17 10.4 0.2 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5357) Peptidase_S46 PF10459.9 CUU98107.1 - 1.4 7.5 8.9 2.3 6.7 8.9 1.2 1 0 0 1 1 1 0 Peptidase S46 Parvo_NS1 PF01057.17 CUU98108.1 - 1.5e-09 37.4 0.1 1.7e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CUU98108.1 - 0.0078 15.1 0.0 0.0084 15.0 0.0 1.0 1 0 0 1 1 1 1 Papillomavirus helicase RNA_helicase PF00910.22 CUU98108.1 - 0.037 14.4 0.0 0.044 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Annexin PF00191.20 CUU98109.1 - 8.4e-82 269.2 13.1 5.4e-18 64.8 0.0 6.0 6 0 0 6 6 6 5 Annexin TFIID_30kDa PF03540.13 CUU98109.1 - 0.11 12.4 0.1 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Ank_2 PF12796.7 CUU98116.1 - 6.4e-27 94.0 7.8 2.5e-13 50.4 0.7 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU98116.1 - 3.4e-15 56.2 3.8 2.2e-11 44.0 0.4 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CUU98116.1 - 4e-14 52.5 4.4 1.6e-08 34.6 1.5 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU98116.1 - 5.5e-12 44.8 1.9 3.7e-05 23.8 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CUU98116.1 - 2.3e-10 40.4 2.7 4.1e-05 23.8 0.2 4.4 4 0 0 4 4 4 2 Ankyrin repeat K_channel_TID PF07941.11 CUU98116.1 - 9.5 6.8 15.3 0.18 12.3 5.2 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain C2 PF00168.30 CUU98120.1 - 0.019 15.3 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 C2 domain LapA_dom PF06305.11 CUU98120.1 - 0.03 14.1 0.8 5.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2773 PF10971.8 CUU98120.1 - 0.14 12.3 0.7 46 4.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2773) NucS PF01939.16 CUU98120.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Endonuclease NucS Clc-like PF07062.12 CUU98120.1 - 1.2 8.5 4.2 13 5.2 0.3 2.2 2 0 0 2 2 2 0 Clc-like TMEM119 PF15724.5 CUU98120.1 - 7.6 6.5 7.3 27 4.7 0.8 2.3 2 0 0 2 2 2 0 TMEM119 family RdRP_3 PF00998.23 CUU98121.1 - 0.085 11.5 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DUF3961 PF13106.6 CUU98121.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) DUF1115 PF06544.12 CUU98122.1 - 0.03 14.4 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Kindlin_2_N PF18124.1 CUU98124.1 - 1.4e-28 98.9 1.1 2e-28 98.4 1.1 1.2 1 0 0 1 1 1 1 Kindlin-2 N-terminal domain 7tm_2 PF00002.24 CUU98126.1 - 3.8e-05 23.1 18.1 0.0014 17.9 10.2 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) NUDIX PF00293.28 CUU98127.1 - 2e-11 44.0 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 CUU98127.1 - 0.03 13.9 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase zf-C2H2_4 PF13894.6 CUU98128.1 - 6e-11 42.2 12.6 0.0024 18.5 0.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CUU98128.1 - 4.8e-10 39.3 11.7 0.0021 18.4 0.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CUU98128.1 - 2.1e-06 27.9 16.2 0.00039 20.7 3.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 CUU98128.1 - 1.4e-05 25.3 6.8 0.049 14.0 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CUU98128.1 - 7e-05 23.0 8.5 0.44 10.9 5.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CUU98128.1 - 0.00094 19.4 4.3 0.00094 19.4 4.3 1.8 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CUU98128.1 - 0.00095 18.9 11.6 0.072 12.9 0.2 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-BED PF02892.15 CUU98128.1 - 0.011 15.7 10.4 0.18 11.9 2.2 3.1 2 1 1 3 3 3 0 BED zinc finger PyrI_C PF02748.15 CUU98128.1 - 0.015 15.2 7.6 0.38 10.7 0.4 3.0 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3795 PF12675.7 CUU98128.1 - 0.022 15.2 2.3 0.031 14.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-C2HE PF16278.5 CUU98128.1 - 0.066 13.7 13.3 40 4.8 9.8 3.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 CUU98128.1 - 0.089 12.8 2.2 0.54 10.3 2.2 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 CUU98128.1 - 0.093 12.7 5.3 7.5 6.6 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 LIM PF00412.22 CUU98128.1 - 0.093 13.0 8.9 2.2 8.6 3.9 2.7 1 1 1 2 2 2 0 LIM domain zf-C2H2_3rep PF18868.1 CUU98128.1 - 0.14 12.9 6.7 1.2 9.8 3.8 2.5 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 CUU98128.1 - 0.2 11.8 2.9 16 5.7 0.0 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 CUU98128.1 - 0.22 11.7 4.7 19 5.5 0.2 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger Elf1 PF05129.13 CUU98128.1 - 0.49 10.5 11.0 1.9 8.6 6.2 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 CUU98128.1 - 1.2 9.2 8.4 36 4.5 0.1 3.0 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_8 PF15909.5 CUU98128.1 - 1.6 9.1 7.5 0.87 9.9 3.7 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf_Hakai PF18408.1 CUU98128.1 - 2.2 8.0 5.7 7.4 6.4 0.2 2.8 3 1 0 3 3 3 0 C2H2 Hakai zinc finger domain PHD_2 PF13831.6 CUU98128.1 - 2.5 7.7 6.8 18 5.0 0.1 3.2 3 0 0 3 3 3 0 PHD-finger zinc_ribbon_10 PF10058.9 CUU98128.1 - 5.3 6.9 6.9 18 5.1 3.5 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 CUU98128.1 - 9 6.3 11.0 62 3.6 4.7 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Plexin_cytopl PF08337.12 CUU98129.1 - 0.026 13.2 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain CRISPR_Cas9_WED PF18061.1 CUU98131.1 - 0.07 13.2 0.2 11 6.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-Cas9 WED domain DUF764 PF05561.11 CUU98132.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) Epiglycanin_TR PF05647.11 CUU98135.1 - 0.19 11.7 2.7 0.3 11.0 2.7 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like DVL PF08137.12 CUU98135.1 - 0.33 10.9 0.7 0.51 10.2 0.7 1.3 1 0 0 1 1 1 0 DVL family DUF2587 PF10759.9 CUU98138.1 - 0.088 12.3 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2587 PF10759.9 CUU98139.1 - 0.088 12.3 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CAP PF00188.26 CUU98141.1 - 3.2e-12 47.4 1.9 1.1e-11 45.6 1.9 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Otopetrin PF03189.13 CUU98143.1 - 0.0023 16.8 0.9 0.0023 16.8 0.9 1.3 2 0 0 2 2 2 1 Otopetrin SdpI PF13630.6 CUU98143.1 - 0.066 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF1674 PF07896.12 CUU98145.1 - 1e-08 35.5 4.9 1.8e-08 34.7 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DCAF15_WD40 PF14939.6 CUU98145.1 - 0.00089 19.0 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat cwf18 PF08315.12 CUU98146.1 - 8.4e-32 110.7 2.3 1.4e-31 109.9 2.3 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor ABC2_membrane_5 PF13346.6 CUU98148.1 - 1.8 8.1 21.0 2.3 7.7 21.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Plectin PF00681.20 CUU98149.1 - 3e-06 27.0 0.0 0.23 11.4 0.0 4.8 5 0 0 5 5 5 2 Plectin repeat CoaE PF01121.20 CUU98150.1 - 2.6e-39 134.7 0.0 3.2e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 CUU98150.1 - 0.004 17.4 0.0 0.0055 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CUU98150.1 - 0.0069 16.9 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CUU98150.1 - 0.013 15.7 0.0 0.013 15.7 0.0 1.2 1 1 0 1 1 1 0 AAA domain DUF348 PF03990.14 CUU98150.1 - 0.035 13.9 0.2 0.082 12.7 0.2 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain HEAT PF02985.22 CUU98152.1 - 2.2e-13 49.2 5.1 0.00067 19.7 0.1 7.7 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.8 CUU98152.1 - 7.3e-06 25.7 0.0 0.59 9.7 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.6 CUU98152.1 - 1.2e-05 25.6 0.1 0.094 13.1 0.1 4.3 4 2 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 CUU98152.1 - 1.6e-05 25.3 4.2 0.00082 19.8 0.4 4.2 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 CUU98152.1 - 0.0081 16.2 0.0 0.21 11.6 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CUU98152.1 - 0.01 16.4 0.0 0.069 13.8 0.0 2.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 CUU98152.1 - 0.021 13.9 0.0 0.17 10.9 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF1221 PF06760.11 CUU98152.1 - 0.053 13.0 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) Pox_Ag35 PF03286.14 CUU98154.1 - 1.1 9.0 11.9 1.6 8.5 11.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RT_RNaseH_2 PF17919.1 CUU98157.1 - 2e-14 53.4 0.1 2.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CUU98157.1 - 6.6e-08 32.8 0.1 1.3e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Sde2_N_Ubi PF13019.6 CUU98160.1 - 1.5 8.7 3.9 0.95 9.3 0.9 2.0 2 1 1 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain Cas_Csm6 PF09659.10 CUU98161.1 - 0.12 11.1 1.4 6.6 5.4 0.2 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Glyco_hydr_116N PF12215.8 CUU98162.1 - 8.7e-61 206.1 0.0 1e-60 205.9 0.0 1.1 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Mannosyl_trans PF05007.13 CUU98163.1 - 1.4e-36 126.7 17.2 2.7e-30 106.1 2.9 2.4 3 0 0 3 3 3 2 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CUU98163.1 - 4.2e-11 42.5 5.0 4.2e-11 42.5 5.0 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CUU98163.1 - 6.6e-06 26.0 13.3 1.4e-05 24.9 13.3 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 87 PMT_2 PF13231.6 CUU98163.1 - 0.014 15.7 15.4 0.26 11.5 2.0 2.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Exo_endo_phos_2 PF14529.6 CUU98165.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AHL_synthase PF17327.2 CUU98165.1 - 0.0061 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Acyl homoserine lactone synthase TGT PF01702.18 CUU98166.1 - 0.061 12.5 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase tRNA_bind_2 PF13725.6 CUU98167.1 - 2.1e-24 86.5 1.0 2.6e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Possible tRNA binding domain GNAT_acetyltr_2 PF13718.6 CUU98167.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2967 PF11179.8 CUU98168.1 - 0.2 9.7 1.4 0.24 9.5 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Menin PF05053.13 CUU98169.1 - 0.29 9.4 4.6 0.48 8.7 4.6 1.3 1 0 0 1 1 1 0 Menin Smg8_Smg9 PF10220.9 CUU98169.1 - 0.95 7.7 3.7 1.3 7.3 3.7 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DNA_pol_phi PF04931.13 CUU98169.1 - 1.1 7.3 9.3 1.5 6.8 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CUU98169.1 - 2.7 7.7 7.0 0.19 11.4 1.4 2.0 2 0 0 2 2 2 0 FAM176 family Sec23_trunk PF04811.15 CUU98170.1 - 9.6e-15 54.8 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CUU98170.1 - 1.6e-13 50.5 12.7 2.7e-13 49.7 12.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ion_trans_N PF08412.10 CUU98173.1 - 3.1e-22 77.9 0.2 6e-22 77.0 0.2 1.5 1 0 0 1 1 1 1 Ion transport protein N-terminal DUF4390 PF14334.6 CUU98175.1 - 0.11 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Homeodomain PF00046.29 CUU98176.1 - 8e-11 41.6 1.6 1.4e-10 40.8 1.6 1.4 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 CUU98176.1 - 0.009 15.9 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Fe_dep_repress PF01325.19 CUU98176.1 - 0.013 15.7 0.4 0.026 14.7 0.4 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 CUU98176.1 - 0.014 15.2 0.3 0.023 14.5 0.3 1.3 1 0 0 1 1 1 0 Homeodomain-like domain MarR PF01047.22 CUU98176.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 MarR family ExoD PF06055.12 CUU98177.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Arrestin_N PF00339.29 CUU98179.1 - 9.3e-13 48.5 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Parvo_NS1 PF01057.17 CUU98180.1 - 0.008 15.3 0.1 0.0086 15.2 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Trypsin PF00089.26 CUU98182.1 - 1.6e-07 31.3 0.0 3.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CUU98182.1 - 0.13 12.7 0.1 0.71 10.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Kelch_1 PF01344.25 CUU98185.1 - 8.4e-09 34.9 0.1 1.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CUU98185.1 - 4.8e-07 29.6 0.1 9.8e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 CUU98185.1 - 0.00017 21.7 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CUU98185.1 - 0.00088 19.2 0.1 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CUU98185.1 - 0.061 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.6 CUU98185.1 - 0.11 12.8 0.0 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain EGF PF00008.27 CUU98186.1 - 3.8e-09 36.7 17.4 3.3e-06 27.3 2.4 3.5 3 0 0 3 3 2 2 EGF-like domain EGF_2 PF07974.13 CUU98186.1 - 1e-05 25.8 33.1 0.00017 21.9 8.2 3.3 3 0 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 CUU98186.1 - 5.4e-05 23.3 23.5 0.0046 17.1 1.9 3.5 3 0 0 3 3 3 2 EGF domain hEGF PF12661.7 CUU98186.1 - 0.00018 22.0 4.6 0.00018 22.0 4.6 4.2 4 1 1 5 5 5 2 Human growth factor-like EGF DUF2561 PF10812.8 CUU98186.1 - 0.02 15.0 0.4 0.031 14.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3844 PF12955.7 CUU98186.1 - 0.021 15.0 13.0 0.18 12.0 3.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3844) DUF3827 PF12877.7 CUU98186.1 - 0.064 11.6 0.1 0.11 10.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3827) DUF5385 PF17359.2 CUU98186.1 - 0.16 11.5 0.9 0.27 10.8 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SIT PF15330.6 CUU98186.1 - 0.29 11.6 1.4 7.6 7.0 0.0 2.6 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT SKG6 PF08693.10 CUU98186.1 - 0.68 9.4 7.5 1.2 8.6 7.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plasmod_Pvs28 PF06247.11 CUU98186.1 - 2.2 8.7 18.7 0.57 10.5 1.8 3.3 2 1 0 2 2 2 0 Pvs28 EGF domain ASFV_J13L PF05568.11 CUU98186.1 - 4.7 6.9 7.6 15 5.3 4.6 2.2 1 1 1 2 2 2 0 African swine fever virus J13L protein dNK PF01712.19 CUU98187.1 - 2.4e-28 99.4 0.0 5.1e-23 82.0 0.0 2.0 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 CUU98187.1 - 0.0037 17.8 0.3 0.029 14.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CUU98187.1 - 0.017 15.3 0.1 0.032 14.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain TRAPPC10 PF12584.8 CUU98187.1 - 0.035 13.8 0.0 2.5 7.8 0.0 2.1 1 1 1 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 NTP_transf_2 PF01909.23 CUU98187.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain IMS_HHH PF11798.8 CUU98187.1 - 0.096 13.1 0.1 19 5.8 0.0 2.4 1 1 1 2 2 2 0 IMS family HHH motif Thymidylate_kin PF02223.17 CUU98187.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Rop-like PF05082.13 CUU98187.1 - 0.22 11.3 2.3 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Rop-like CoaE PF01121.20 CUU98188.1 - 8.9e-06 25.5 0.1 1.2e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase VEGFR-2_TMD PF17988.1 CUU98188.1 - 7.9 6.0 6.5 13 5.3 6.5 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain MFS_2 PF13347.6 CUU98189.1 - 8.6e-42 143.2 8.1 9.5e-42 143.0 8.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CUU98189.1 - 0.0028 16.6 13.1 0.0028 16.6 13.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 CUU98189.1 - 2.2 8.6 5.0 2.5 8.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) E1-E2_ATPase PF00122.20 CUU98189.1 - 9.6 5.7 8.4 6.7 6.2 0.4 2.3 2 0 0 2 2 2 0 E1-E2 ATPase MutS_I PF01624.20 CUU98190.1 - 9.7e-29 99.9 0.4 1.4e-18 67.2 0.1 2.3 1 1 1 2 2 2 2 MutS domain I PAF PF15715.5 CUU98190.1 - 0.14 12.8 3.8 0.14 12.8 2.5 1.7 1 1 0 1 1 1 0 PCNA-associated factor histone like domain tify PF06200.14 CUU98191.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain PDZ_6 PF17820.1 CUU98192.1 - 0.082 12.8 0.1 9.1 6.2 0.1 2.7 2 0 0 2 2 2 0 PDZ domain MS_channel PF00924.18 CUU98194.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel DDRGK PF09756.9 CUU98194.1 - 0.045 13.3 0.9 0.051 13.2 0.9 1.1 1 0 0 1 1 1 0 DDRGK domain PP2C PF00481.21 CUU98196.1 - 5.4e-70 236.0 0.0 7.5e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CUU98196.1 - 6e-17 61.9 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.6 CUU98196.1 - 0.0023 17.6 0.0 0.0075 15.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 CUU98197.1 - 1.9e-35 122.5 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98197.1 - 4.4e-09 36.0 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AcetylCoA_hyd_C PF13336.6 CUU98198.1 - 4e-58 195.7 0.0 7.1e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CUU98198.1 - 3.8e-20 72.7 0.0 7.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.22 CUU98198.1 - 0.0022 18.0 0.0 0.9 9.5 0.0 3.0 3 1 0 3 3 3 2 DeoR C terminal sensor domain YqgC PF17430.2 CUU98201.1 - 0.18 11.9 0.2 2.7 8.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized YqgC-like fn3 PF00041.21 CUU98205.1 - 1.1e-05 25.7 1.6 0.016 15.6 0.0 2.3 2 1 0 2 2 2 2 Fibronectin type III domain Prefoldin_2 PF01920.20 CUU98206.1 - 1.9e-15 56.7 0.6 2.2e-15 56.5 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PABP PF00658.18 CUU98206.1 - 0.036 14.2 0.1 0.33 11.2 0.1 2.0 1 1 1 2 2 2 0 Poly-adenylate binding protein, unique domain Complex1_LYR PF05347.15 CUU98208.1 - 2.6e-12 46.6 0.4 5.6e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CUU98208.1 - 0.0021 18.8 0.7 0.0035 18.0 0.7 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Tom37_C PF11801.8 CUU98208.1 - 0.063 13.2 0.2 0.077 13.0 0.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Dynein_light PF01221.18 CUU98209.1 - 8.1e-31 106.2 0.0 3.2e-17 62.6 0.0 2.0 2 0 0 2 2 2 2 Dynein light chain type 1 Phage_holin_6_1 PF09682.10 CUU98209.1 - 0.021 15.2 0.2 0.97 9.9 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ground-like PF04155.18 CUU98209.1 - 0.051 14.2 0.0 0.55 10.9 0.0 2.2 2 0 0 2 2 2 0 Ground-like domain FIVAR PF07554.13 CUU98209.1 - 0.055 14.2 0.3 2.7 8.8 0.1 2.2 2 0 0 2 2 2 0 FIVAR domain Porin_2 PF02530.14 CUU98209.1 - 0.12 11.7 0.0 1.3 8.2 0.0 1.9 1 1 1 2 2 2 0 Porin subfamily tify PF06200.14 CUU98213.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain PLAT PF01477.23 CUU98214.1 - 1.5e-28 99.7 0.7 2.6e-22 79.6 0.2 2.2 2 0 0 2 2 2 2 PLAT/LH2 domain Enterotoxin_HS1 PF08090.11 CUU98214.1 - 0.072 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 Methyltransf_31 PF13847.6 CUU98215.1 - 3.5e-19 69.1 0.0 5.4e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CUU98215.1 - 1.2e-11 45.2 0.0 4.2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CUU98215.1 - 6.5e-11 42.3 0.0 1.9e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CUU98215.1 - 4.1e-10 40.2 0.0 7.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CUU98215.1 - 3.5e-09 37.3 0.0 6.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CUU98215.1 - 3.5e-07 30.1 0.0 8.4e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 CUU98215.1 - 2.7e-06 27.0 0.0 8.1e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 CUU98215.1 - 4.6e-06 26.2 0.1 7.6e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_20 PF12147.8 CUU98215.1 - 9.5e-05 21.7 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 CUU98215.1 - 0.00031 20.8 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CUU98215.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CUU98215.1 - 0.0022 17.9 0.0 0.013 15.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CUU98215.1 - 0.0035 16.7 0.1 0.0095 15.3 0.0 1.8 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 CUU98215.1 - 0.0047 16.5 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 CUU98215.1 - 0.0048 15.9 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 CUU98215.1 - 0.054 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Pox_MCEL PF03291.16 CUU98215.1 - 0.058 12.5 0.1 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 mRNA capping enzyme MetW PF07021.12 CUU98215.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 CUU98215.1 - 0.085 11.8 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 CUU98215.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TORC_M PF12885.7 CUU98216.1 - 0.12 12.3 1.9 0.19 11.6 0.9 1.8 1 1 1 2 2 2 0 Transducer of regulated CREB activity middle domain DUF2568 PF10823.8 CUU98216.1 - 1.7 9.0 11.9 0.41 11.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) MutS_V PF00488.21 CUU98219.1 - 1e-71 240.9 0.1 1.6e-71 240.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CUU98219.1 - 0.016 15.5 0.2 0.038 14.2 0.1 1.7 2 0 0 2 2 2 0 MutS domain III WD40 PF00400.32 CUU98220.1 - 0.0007 20.4 0.3 0.57 11.1 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L14e PF01929.17 CUU98220.1 - 0.0026 18.2 0.3 0.0074 16.8 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L14 GCP_C_terminal PF04130.13 CUU98221.1 - 9.9e-30 104.1 9.4 2.1e-29 103.0 8.3 2.1 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CUU98221.1 - 2.4e-16 60.2 0.9 7.1e-16 58.7 0.1 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal IRK PF01007.20 CUU98221.1 - 0.063 13.1 4.4 0.71 9.7 0.3 2.6 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain RPN7 PF10602.9 CUU98221.1 - 0.081 12.6 0.7 0.14 11.9 0.7 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Pkinase PF00069.25 CUU98222.1 - 3e-37 128.4 0.0 3.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98222.1 - 4.1e-18 65.6 0.0 5.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CUU98222.1 - 0.00011 21.1 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CUU98222.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CUU98222.1 - 0.023 14.6 0.4 0.062 13.2 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PepSY_like PF11396.8 CUU98222.1 - 0.026 15.1 0.1 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like RIO1 PF01163.22 CUU98222.1 - 0.052 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RVT_3 PF13456.6 CUU98222.1 - 0.069 13.0 0.0 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Pox_ser-thr_kin PF05445.11 CUU98222.1 - 0.1 11.6 1.0 0.5 9.3 0.1 2.3 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Lambda_CIII PF02061.16 CUU98223.1 - 0.055 13.5 0.3 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Lambda Phage CIII DASH_Dad4 PF08650.10 CUU98223.1 - 1.3 9.0 3.6 1.9 8.5 1.9 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad4 tify PF06200.14 CUU98224.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain EF_assoc_2 PF08356.12 CUU98227.1 - 1.6e-17 63.2 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 EF hand associated SLBP_RNA_bind PF15247.6 CUU98228.1 - 8.5e-23 80.3 4.4 8.5e-23 80.3 4.4 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain RRM_1 PF00076.22 CUU98229.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CUU98229.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 RL domain Argos PF11581.8 CUU98230.1 - 0.0002 21.4 5.6 0.00047 20.2 5.6 1.6 1 1 0 1 1 1 1 Antagonist of EGFR signalling, Argos PIP5K PF01504.18 CUU98232.1 - 1e-26 93.8 0.1 1.6e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CBM_21 PF03370.13 CUU98233.1 - 2.3e-26 92.2 0.2 4.2e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CUU98233.1 - 5.6e-10 39.7 1.0 1.3e-09 38.5 1.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Lipocalin_2 PF08212.12 CUU98234.1 - 0.074 13.0 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Lipocalin-like domain BET PF17035.5 CUU98235.1 - 1.3e-07 31.6 1.3 2.3e-07 30.9 1.3 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CUU98235.1 - 1e-05 25.5 3.0 1.1e-05 25.4 0.3 2.2 2 1 1 3 3 3 1 Bromodomain HipN PF18253.1 CUU98235.1 - 0.036 13.8 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Endosulfine PF04667.17 CUU98235.1 - 0.043 13.9 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region MRP-L51 PF10244.9 CUU98235.1 - 0.052 13.8 0.3 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit DUF3384 PF11864.8 CUU98235.1 - 0.093 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) TMEM223 PF14640.6 CUU98236.1 - 1.3e-14 54.7 0.1 3e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 223 RRM_1 PF00076.22 CUU98236.1 - 1.5e-11 43.9 0.0 3.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exonuc_VII_S PF02609.16 CUU98236.1 - 0.43 10.7 3.6 0.54 10.4 1.9 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF1201 PF06716.11 CUU98236.1 - 1.1 9.4 5.2 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) BET PF17035.5 CUU98237.1 - 1.3e-07 31.6 1.3 2.3e-07 30.9 1.3 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CUU98237.1 - 1e-05 25.5 3.0 1.1e-05 25.4 0.3 2.2 2 1 1 3 3 3 1 Bromodomain HipN PF18253.1 CUU98237.1 - 0.036 13.8 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Endosulfine PF04667.17 CUU98237.1 - 0.043 13.9 0.1 0.093 12.9 0.1 1.6 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region MRP-L51 PF10244.9 CUU98237.1 - 0.052 13.8 0.3 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit DUF3384 PF11864.8 CUU98237.1 - 0.093 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) HLH PF00010.26 CUU98238.1 - 0.014 15.4 0.3 0.031 14.3 0.3 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF3216 PF11505.8 CUU98238.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) RhoGAP-FF1 PF16512.5 CUU98241.1 - 0.018 15.7 0.1 0.029 15.0 0.1 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain SbsC_C PF18058.1 CUU98241.1 - 0.043 14.1 0.2 0.057 13.7 0.2 1.2 1 0 0 1 1 1 0 SbsC C-terminal domain tify PF06200.14 CUU98246.1 - 0.14 11.5 1.8 0.66 9.4 0.2 2.3 2 0 0 2 2 2 0 tify domain ATP-synt_C PF00137.21 CUU98247.1 - 9.6e-11 41.9 12.5 1.5e-10 41.2 12.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_C PF00137.21 CUU98248.1 - 9.6e-11 41.9 12.5 1.5e-10 41.2 12.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Cpn60_TCP1 PF00118.24 CUU98249.1 - 1.1e-147 492.6 11.0 1.3e-147 492.4 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mon2_C PF16206.5 CUU98250.1 - 4.5e-25 88.0 0.1 2.8e-22 78.7 0.1 2.2 2 0 0 2 2 2 2 C-terminal region of Mon2 protein CAP PF00188.26 CUU98252.1 - 9.6e-15 55.5 5.3 1.6e-14 54.8 5.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Aurora-A_bind PF09041.10 CUU98252.1 - 0.0023 18.0 0.7 0.0044 17.1 0.7 1.4 1 0 0 1 1 1 1 Aurora-A binding 2CSK_N PF08521.10 CUU98252.1 - 0.083 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal MFS_1 PF07690.16 CUU98253.1 - 4.5e-06 25.8 7.1 5.3e-06 25.6 7.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 CUU98253.1 - 0.033 14.4 2.9 0.065 13.5 2.9 1.6 1 0 0 1 1 1 0 Transglycosylase associated protein DUF2568 PF10823.8 CUU98253.1 - 0.071 13.4 3.5 0.12 12.7 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) Sugar_tr PF00083.24 CUU98253.1 - 0.39 9.5 8.8 0.47 9.2 8.6 1.2 1 1 0 1 1 1 0 Sugar (and other) transporter ydhR PF08803.11 CUU98254.1 - 0.036 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR tify PF06200.14 CUU98255.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain YabA PF06156.13 CUU98256.1 - 0.13 12.9 0.1 0.27 11.9 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 CUU98256.1 - 0.27 11.5 1.7 0.51 10.6 1.7 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Sugarporin_N PF11471.8 CUU98256.1 - 0.29 11.1 2.1 0.59 10.1 2.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SPX PF03105.19 CUU98256.1 - 0.36 10.7 10.4 0.43 10.4 10.4 1.1 1 0 0 1 1 1 0 SPX domain MFS_2 PF13347.6 CUU98258.1 - 2.7e-33 115.2 10.5 1.1e-28 99.9 4.3 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Shadoo PF14999.6 CUU98258.1 - 0.046 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Phage_holin_3_6 PF07332.11 CUU98258.1 - 9.1 6.4 7.1 6.8 6.8 4.0 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_2 PF13347.6 CUU98259.1 - 3.4e-15 55.5 0.1 3.9e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_2 PF13347.6 CUU98260.1 - 2.7e-33 115.2 10.5 1.1e-28 99.9 4.3 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Shadoo PF14999.6 CUU98260.1 - 0.046 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Phage_holin_3_6 PF07332.11 CUU98260.1 - 9.1 6.4 7.1 6.8 6.8 4.0 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Proteasome PF00227.26 CUU98261.1 - 1.1e-40 139.2 0.0 1.6e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 CUU98261.1 - 1.5e-10 41.9 0.6 4.2e-10 40.5 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CUU98261.1 - 2.3e-05 24.7 0.2 6.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CD36 PF01130.21 CUU98262.1 - 3.3e-46 157.8 0.8 4.7e-37 127.6 0.1 2.0 1 1 1 2 2 2 2 CD36 family DUF5084 PF16894.5 CUU98264.1 - 0.22 11.9 8.7 0.043 14.3 4.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5084) 7tm_2 PF00002.24 CUU98266.1 - 0.00022 20.6 0.3 0.00042 19.7 0.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Lamp PF01299.17 CUU98268.1 - 5.7e-05 23.0 2.0 0.00092 19.1 0.4 3.1 3 1 1 4 4 4 1 Lysosome-associated membrane glycoprotein (Lamp) JmjN PF02375.17 CUU98272.1 - 5.9e-16 58.1 0.7 1.2e-15 57.1 0.7 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 CUU98272.1 - 2.2e-15 57.1 1.1 3.7e-15 56.4 1.1 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TIP49 PF06068.13 CUU98273.1 - 6.4e-161 535.4 2.6 1e-160 534.8 2.6 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CUU98273.1 - 3e-25 88.1 1.0 7.9e-25 86.8 1.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CUU98273.1 - 4.4e-11 43.3 1.3 8.9e-08 32.6 0.1 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CUU98273.1 - 2.3e-07 30.9 0.1 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CUU98273.1 - 5.3e-07 29.5 0.6 0.00038 20.2 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CUU98273.1 - 1.1e-05 25.9 0.1 3.8e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CUU98273.1 - 3.2e-05 23.4 0.8 0.00052 19.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CUU98273.1 - 7.5e-05 23.1 2.4 0.0019 18.6 1.7 2.7 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CUU98273.1 - 8.1e-05 22.9 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CUU98273.1 - 0.00025 20.7 0.2 0.00051 19.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CUU98273.1 - 0.00055 19.3 0.1 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 CUU98273.1 - 0.0033 17.2 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CUU98273.1 - 0.0076 15.8 0.1 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CUU98273.1 - 0.0096 16.1 0.2 0.026 14.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CUU98273.1 - 0.0097 15.4 1.4 0.52 9.7 0.3 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 CUU98273.1 - 0.0099 16.1 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CUU98273.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CUU98273.1 - 0.013 15.3 0.8 0.16 11.6 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CUU98273.1 - 0.013 16.0 0.1 0.058 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CUU98273.1 - 0.028 14.1 0.2 0.056 13.2 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CUU98273.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CUU98273.1 - 0.043 13.8 0.2 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CUU98273.1 - 0.065 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CUU98273.1 - 0.073 13.1 3.0 0.084 12.9 0.2 2.4 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CUU98273.1 - 0.079 12.2 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CUU98273.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.25 CUU98274.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98274.1 - 0.003 16.9 0.0 0.0049 16.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU98275.1 - 2.3e-11 43.6 0.0 2.9e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98275.1 - 4.1e-08 32.8 0.0 4.8e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase 7TM_GPCR_Srw PF10324.9 CUU98277.1 - 3.3e-27 95.6 12.8 3.9e-15 55.9 6.5 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.21 CUU98277.1 - 2.4e-11 43.5 6.5 4.5e-11 42.6 6.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CUU98277.1 - 7.5e-06 25.8 6.5 2.1e-05 24.3 6.5 1.8 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Pho86 PF11124.8 CUU98277.1 - 2.3 7.6 9.9 0.16 11.4 1.1 2.3 1 1 0 2 2 2 0 Inorganic phosphate transporter Pho86 Exo_endo_phos_2 PF14529.6 CUU98279.1 - 0.00075 19.3 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CUU98279.1 - 0.047 13.2 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-H2C2_2 PF13465.6 CUU98280.1 - 3.6e-05 24.0 27.0 0.0029 18.0 2.4 7.8 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 CUU98280.1 - 0.00024 21.4 4.2 0.00024 21.4 4.2 6.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU98280.1 - 0.035 14.9 3.0 0.035 14.9 3.0 6.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 CUU98280.1 - 0.17 12.4 18.3 0.3 11.6 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CUU98280.1 - 0.35 11.2 11.9 4.6 7.7 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 CUU98280.1 - 1.1 9.0 2.9 2.1 8.0 2.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) AXH PF08517.12 CUU98281.1 - 7.2e-08 33.0 0.0 5.5e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Ataxin-1 and HBP1 module (AXH) AAA_35 PF14516.6 CUU98281.1 - 0.15 10.9 0.0 5 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATP_bind_3 PF01171.20 CUU98282.1 - 6.2e-09 35.9 0.1 1.4e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 PP-loop family Peptidase_M22 PF00814.25 CUU98282.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family Glyco_hydro38C2 PF17677.1 CUU98283.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain FTA4 PF13093.6 CUU98284.1 - 0.017 15.0 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sld5 PF05916.11 CUU98284.1 - 0.044 14.3 0.5 0.052 14.0 0.5 1.1 1 0 0 1 1 1 0 GINS complex protein Pox_A_type_inc PF04508.12 CUU98284.1 - 1.8 8.5 6.0 3.9 7.5 0.4 2.9 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Acetyltransf_11 PF13720.6 CUU98285.1 - 0.066 13.7 4.8 2.8 8.5 0.0 4.5 3 1 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 UPF0113_N PF17833.1 CUU98285.1 - 0.11 13.1 0.5 0.93 10.1 0.2 2.8 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain Rad51 PF08423.11 CUU98286.1 - 3.3e-09 36.4 0.0 3.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 7TM_GPCR_Srw PF10324.9 CUU98287.1 - 2.6e-14 53.2 7.5 4.2e-14 52.6 7.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Mon2_C PF16206.5 CUU98287.1 - 2.6e-05 22.6 0.6 5.6e-05 21.5 0.6 1.6 1 1 0 1 1 1 1 C-terminal region of Mon2 protein 7TM_GPCR_Srx PF10328.9 CUU98287.1 - 9.3e-05 22.2 8.3 0.00018 21.3 8.3 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.21 CUU98287.1 - 0.00061 19.2 5.8 0.0013 18.1 5.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF936 PF06075.12 CUU98289.1 - 2.7 6.8 42.4 3.3 6.5 42.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Asp-B-Hydro_N PF05279.11 CUU98289.1 - 3.6 7.6 12.6 4.3 7.3 12.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4902 PF16245.5 CUU98290.1 - 0.14 12.1 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) SH3_2 PF07653.17 CUU98291.1 - 4.3e-08 32.7 0.0 6.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CUU98291.1 - 3e-07 29.9 0.0 3.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CUU98291.1 - 0.00097 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CUU98291.1 - 0.0041 17.4 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 CUU98291.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 1 1 2 2 2 0 Bacterial SH3 domain UPRTase PF14681.6 CUU98292.1 - 1.2e-54 184.9 0.0 1.4e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RL10P_insert PF17777.1 CUU98292.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P PapD-like PF14874.6 CUU98294.1 - 0.13 12.5 0.1 2.4 8.4 0.1 2.1 1 1 1 2 2 2 0 Flagellar-associated PapD-like SIT PF15330.6 CUU98295.1 - 0.13 12.7 0.7 0.25 11.8 0.7 1.5 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Sugar_tr PF00083.24 CUU98298.1 - 4.9e-26 91.6 20.5 8.1e-26 90.9 20.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CUU98298.1 - 5.4e-20 71.6 23.9 5.4e-20 71.6 23.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RhoGEF PF00621.20 CUU98301.1 - 0.023 14.9 0.2 0.032 14.5 0.2 1.2 1 0 0 1 1 1 0 RhoGEF domain 7tm_1 PF00001.21 CUU98304.1 - 2.3e-07 30.4 4.0 5.6e-07 29.1 4.0 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LicD PF04991.13 CUU98307.1 - 6.1e-11 42.9 3.4 6.2e-11 42.9 2.4 1.5 1 1 0 1 1 1 1 LicD family Reovirus_M2 PF05993.12 CUU98307.1 - 0.057 11.5 0.0 0.07 11.2 0.0 1.0 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) RA PF00788.23 CUU98308.1 - 4.9e-09 36.7 0.0 6.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Sushi PF00084.20 CUU98309.1 - 3.2e-07 30.8 2.0 3.5e-05 24.3 0.1 2.4 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) ig PF00047.25 CUU98311.1 - 0.055 13.7 0.1 0.075 13.2 0.1 1.2 1 0 0 1 1 1 0 Immunoglobulin domain Mon2_C PF16206.5 CUU98312.1 - 1.3e-35 122.8 0.1 1.6e-35 122.6 0.1 1.0 1 0 0 1 1 1 1 C-terminal region of Mon2 protein K_channel_TID PF07941.11 CUU98312.1 - 0.31 11.5 3.9 0.5 10.9 3.9 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Furin-like_2 PF15913.5 CUU98314.1 - 2e-05 24.7 16.2 3e-05 24.1 16.2 1.3 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich DUF4215 PF13948.6 CUU98314.1 - 0.0024 18.2 1.4 0.0024 18.2 1.4 3.4 3 2 1 4 4 4 2 Domain of unknown function (DUF4215) Ig_3 PF13927.6 CUU98315.1 - 0.0094 16.5 0.0 1 10.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CUU98315.1 - 0.015 15.4 0.0 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin domain Ig_6 PF18452.1 CUU98315.1 - 0.043 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 CUU98315.1 - 0.068 13.4 0.1 6.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin V-set domain I-set PF07679.16 CUU98316.1 - 1.4e-27 95.6 0.0 7.5e-12 45.2 0.0 3.8 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CUU98316.1 - 1.1e-24 86.8 0.6 1.6e-09 38.2 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CUU98316.1 - 8.9e-17 61.2 0.2 4.1e-05 23.8 0.1 4.5 4 1 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 CUU98316.1 - 1e-15 57.7 0.0 6e-06 26.3 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.17 CUU98316.1 - 1.4e-12 47.7 0.2 3.3e-05 24.0 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin V-set domain Ig_C17orf99 PF17736.1 CUU98316.1 - 0.00054 19.9 0.3 0.62 10.1 0.0 3.1 2 2 0 2 2 2 2 C17orf99 Ig domain C2-set PF05790.15 CUU98316.1 - 0.02 15.1 0.0 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 CUU98316.1 - 0.12 12.5 0.0 2.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain RVT_1 PF00078.27 CUU98317.1 - 1.9e-11 43.9 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) fn3 PF00041.21 CUU98320.1 - 3.9e-13 49.6 0.1 1.3e-07 31.8 0.0 2.7 2 1 0 2 2 2 2 Fibronectin type III domain Interfer-bind PF09294.10 CUU98320.1 - 0.15 12.4 0.3 1.5 9.2 0.0 2.5 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Mon2_C PF16206.5 CUU98321.1 - 1.1e-44 152.9 5.2 4.9e-42 144.1 0.2 2.7 1 1 1 2 2 2 2 C-terminal region of Mon2 protein K_channel_TID PF07941.11 CUU98321.1 - 0.7 10.4 3.9 1.6 9.3 3.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Acatn PF13000.7 CUU98322.1 - 0.00055 18.6 3.3 0.00055 18.6 3.3 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 FHA PF00498.26 CUU98324.1 - 1.4e-09 38.1 0.1 3.3e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 FHA domain USP7_ICP0_bdg PF12436.8 CUU98324.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Arrestin_N PF00339.29 CUU98325.1 - 8.6e-13 48.6 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-C2H2_jaz PF12171.8 CUU98326.1 - 0.091 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mt_ATP-synt_B PF05405.14 CUU98327.1 - 0.008 15.8 0.2 0.014 15.1 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ZT_dimer PF16916.5 CUU98327.1 - 0.0081 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Guanylate_cyc PF00211.20 CUU98329.1 - 3.7e-28 98.4 0.1 4.6e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CUU98329.1 - 0.0013 18.2 0.9 0.0017 17.8 0.9 1.2 1 0 0 1 1 1 1 Heme NO binding associated Parvo_NS1 PF01057.17 CUU98331.1 - 7.2e-06 25.3 0.1 8.3e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 EF-hand_7 PF13499.6 CUU98336.1 - 1e-08 35.5 0.6 1.2e-08 35.2 0.6 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CUU98336.1 - 5.7e-08 32.1 2.7 0.0064 16.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CUU98336.1 - 2.4e-07 29.8 2.8 0.0012 18.3 0.3 2.1 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CUU98336.1 - 8e-05 22.9 0.2 9.5e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CUU98336.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CUU98336.1 - 0.017 14.6 3.6 1.3 8.6 0.3 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CUU98336.1 - 0.025 14.4 0.9 0.077 12.8 0.3 1.9 1 1 1 2 2 2 0 EF-hand domain pair TerB PF05099.13 CUU98336.1 - 0.095 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB C1_1 PF00130.22 CUU98340.1 - 1.6e-08 34.3 6.5 2.3e-08 33.8 6.5 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CUU98340.1 - 0.054 13.8 7.0 0.12 12.7 7.0 1.7 1 0 0 1 1 1 0 C1 domain UQ_con PF00179.26 CUU98341.1 - 5.1e-23 81.3 0.1 5.6e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CUU98341.1 - 0.0085 15.9 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 UEV domain DDE_3 PF13358.6 CUU98342.1 - 0.034 13.9 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease MRP-L27 PF09809.9 CUU98343.1 - 6.7e-11 42.0 0.0 9.8e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Nop14 PF04147.12 CUU98344.1 - 0.00068 18.0 47.1 0.00092 17.6 47.1 1.2 1 0 0 1 1 1 1 Nop14-like family DUF4775 PF16001.5 CUU98344.1 - 1 8.7 46.6 1.3 8.4 46.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) DUF5009 PF16401.5 CUU98346.1 - 0.25 10.8 0.0 0.31 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) zf-C2H2 PF00096.26 CUU98349.1 - 0.033 14.7 1.9 0.033 14.7 1.9 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Y_phosphatase PF00102.27 CUU98350.1 - 1.1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PDZ PF00595.24 CUU98351.1 - 2e-09 37.7 0.2 2.4e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CUU98351.1 - 0.024 14.5 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 PDZ domain Lipoprotein_19 PF13617.6 CUU98352.1 - 0.084 12.7 1.6 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 YnbE-like lipoprotein DUF384 PF04064.13 CUU98353.1 - 6.9e-21 73.9 3.4 7.3e-21 73.8 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.14 CUU98353.1 - 8.3e-16 58.2 0.4 3.6e-14 52.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF383) PUL PF08324.11 CUU98353.1 - 0.00057 19.2 2.7 0.031 13.5 0.6 2.2 1 1 1 2 2 2 2 PUL domain Mito_fiss_reg PF05308.11 CUU98355.1 - 0.11 12.5 3.4 0.13 12.3 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1290 PF06947.12 CUU98355.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) DUF2967 PF11179.8 CUU98356.1 - 0.026 12.6 1.5 0.032 12.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MRC1 PF09444.10 CUU98356.1 - 0.3 11.6 1.9 0.39 11.2 1.9 1.1 1 0 0 1 1 1 0 MRC1-like domain HCO3_cotransp PF00955.21 CUU98357.1 - 3.8e-17 62.3 0.2 4.7e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 HCO3- transporter family fn3 PF00041.21 CUU98358.1 - 9.3e-12 45.1 1.4 2.3e-06 27.8 0.3 3.0 2 1 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CUU98358.1 - 4.9e-05 23.8 2.7 0.25 11.9 0.2 3.1 2 2 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF4577 PF15145.6 CUU98358.1 - 0.0011 19.0 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) PP2 PF14299.6 CUU98358.1 - 0.019 15.0 0.0 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Phloem protein 2 DUF5412 PF17428.2 CUU98358.1 - 0.054 13.3 3.6 5 7.0 0.3 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5412) EphA2_TM PF14575.6 CUU98358.1 - 0.063 14.2 1.5 0.082 13.8 0.4 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain ASH PF15780.5 CUU98358.1 - 0.096 12.9 0.9 1.2 9.4 0.2 2.4 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SIT PF15330.6 CUU98358.1 - 0.14 12.6 0.5 0.25 11.8 0.5 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4446 PF14584.6 CUU98358.1 - 0.19 11.7 0.9 0.32 11.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PRIMA1 PF16101.5 CUU98358.1 - 0.23 11.5 5.6 0.087 12.9 1.7 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HemY_N PF07219.13 CUU98358.1 - 0.3 11.3 0.5 0.5 10.6 0.5 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Vpu PF00558.19 CUU98358.1 - 0.52 10.1 2.4 0.85 9.4 2.4 1.3 1 0 0 1 1 1 0 Vpu protein Baculo_11_kDa PF06143.11 CUU98358.1 - 0.56 9.8 4.8 1.1 8.9 4.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Flp1_like PF16982.5 CUU98358.1 - 0.77 9.2 9.5 1.7 8.1 9.5 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Synaptobrevin PF00957.21 CUU98358.1 - 8.5 6.2 7.5 18 5.2 7.5 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF2198 PF09964.9 CUU98359.1 - 0.0015 18.5 0.8 1.9 8.6 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2198) DUF2061 PF09834.9 CUU98359.1 - 0.019 15.5 6.5 0.83 10.2 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) DUF4190 PF13828.6 CUU98359.1 - 0.043 13.6 2.9 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Defensin_big PF14862.6 CUU98359.1 - 0.045 14.1 0.4 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Big defensin TEX29 PF15839.5 CUU98359.1 - 0.3 11.7 2.2 20 5.8 0.1 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein Foamy_virus_ENV PF03408.14 CUU98359.1 - 1.4 6.6 5.2 3.7 5.3 0.2 2.0 1 1 1 2 2 2 0 Foamy virus envelope protein Fungus-induced PF10917.8 CUU98359.1 - 2.4 8.5 10.0 4.1 7.8 2.0 2.4 2 1 0 2 2 2 0 Fungus-induced protein EF-hand_6 PF13405.6 CUU98360.1 - 2e-11 42.8 3.7 4.2e-06 26.2 1.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CUU98360.1 - 4.7e-10 38.3 4.2 0.00015 21.0 2.7 2.4 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 CUU98360.1 - 5.3e-08 32.0 5.9 0.012 15.1 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CUU98360.1 - 5e-07 30.1 3.6 1.8e-06 28.3 3.6 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CUU98360.1 - 0.0016 18.2 1.8 0.0093 15.8 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair Furin-like_2 PF15913.5 CUU98361.1 - 0.035 14.3 6.2 3.6 7.8 6.2 2.3 1 1 0 1 1 1 0 Furin-like repeat, cysteine-rich Reg_prop PF07494.11 CUU98361.1 - 0.042 14.1 0.1 0.083 13.2 0.1 1.5 1 0 0 1 1 1 0 Two component regulator propeller NCD3G PF07562.14 CUU98361.1 - 1.2 9.2 16.6 1.2e+02 2.7 12.7 3.4 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF4215 PF13948.6 CUU98362.1 - 0.0051 17.2 1.4 0.0051 17.2 1.4 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4215) VSP PF03302.13 CUU98362.1 - 0.011 14.6 19.1 0.11 11.3 8.0 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein Mito_carr PF00153.27 CUU98363.1 - 5.4e-42 141.6 6.5 1.5e-17 63.3 0.3 4.2 2 1 1 3 3 3 3 Mitochondrial carrier protein FlxA PF14282.6 CUU98366.1 - 0.0049 16.8 2.0 0.0092 16.0 2.0 1.4 1 0 0 1 1 1 1 FlxA-like protein Beach PF02138.18 CUU98367.1 - 2.6e-18 66.4 0.0 2.8e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain DUF3258 PF11646.8 CUU98369.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Pkinase_Tyr PF07714.17 CUU98371.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU98371.1 - 3.6e-08 33.1 0.0 3.4e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HECT PF00632.25 CUU98373.1 - 1.9e-18 67.0 0.2 2.2e-18 66.8 0.2 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cyto_heme_lyase PF01265.17 CUU98374.1 - 1.4e-61 208.7 16.5 1.1e-60 205.8 16.5 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ntox37 PF15535.6 CUU98374.1 - 0.065 13.7 1.0 0.065 13.7 1.0 2.4 2 1 1 3 3 3 0 Bacterial toxin 37 Lip_A_acyltrans PF03279.13 CUU98375.1 - 0.081 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase PEX-2N PF09263.10 CUU98375.1 - 0.11 12.9 0.1 15 6.0 0.0 2.3 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal SH2 PF00017.24 CUU98376.1 - 2.1e-05 24.5 0.0 4.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.19 CUU98376.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 RasGEF domain ABC_tran_CTD PF16326.5 CUU98379.1 - 0.0015 18.8 4.4 0.0028 17.9 4.4 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain Sec23_trunk PF04811.15 CUU98379.1 - 0.01 15.4 0.2 0.011 15.3 0.2 1.0 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain DUF2039 PF10217.9 CUU98379.1 - 0.14 12.5 3.3 6.2 7.2 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Kelch_1 PF01344.25 CUU98380.1 - 0.0022 17.6 2.7 4.6 6.9 0.1 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CUU98380.1 - 0.0059 16.9 1.2 12 6.3 0.0 3.2 1 1 2 3 3 3 2 Kelch motif PQQ_3 PF13570.6 CUU98380.1 - 0.079 13.5 0.2 0.62 10.6 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain FERM_M PF00373.18 CUU98381.1 - 0.0027 18.1 0.1 0.0037 17.6 0.1 1.2 1 0 0 1 1 1 1 FERM central domain DLIC PF05783.11 CUU98382.1 - 0.00026 20.0 0.3 0.00033 19.6 0.3 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) NOA36 PF06524.12 CUU98382.1 - 0.081 12.2 2.3 0.17 11.2 2.3 1.5 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.24 CUU98383.1 - 3.1e-07 29.6 11.8 9.9e-07 28.0 11.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4408 PF14364.6 CUU98383.1 - 0.1 12.4 3.6 0.31 10.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) RnaseA PF00074.20 CUU98385.1 - 0.0018 18.7 6.9 0.067 13.6 1.4 3.2 1 1 2 3 3 3 2 Pancreatic ribonuclease MTH865 PF07747.11 CUU98385.1 - 0.0069 16.1 2.1 17 5.3 0.1 3.6 2 1 0 3 3 3 1 MTH865-like family Sigma70_ner PF04546.13 CUU98385.1 - 0.009 15.9 1.9 0.013 15.4 1.5 1.5 1 1 0 1 1 1 1 Sigma-70, non-essential region Phlebovirus_G2 PF07245.11 CUU98385.1 - 0.039 12.4 0.3 0.039 12.4 0.3 1.5 2 0 0 2 2 2 0 Phlebovirus glycoprotein G2 DUF386 PF04074.12 CUU98385.1 - 0.094 12.6 2.3 0.4 10.6 0.4 2.6 1 1 2 3 3 3 0 YhcH/YjgK/YiaL Spc7 PF08317.11 CUU98385.1 - 0.15 10.9 2.1 0.21 10.4 1.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Gemini_C4 PF01492.17 CUU98385.1 - 2.1 8.3 7.2 27 4.8 0.2 3.3 2 1 1 3 3 3 0 Geminivirus C4 protein DUF4223 PF13978.6 CUU98385.1 - 3.4 7.7 6.1 1e+02 3.0 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4223) Mucin PF01456.17 CUU98387.1 - 0.12 12.3 25.2 0.21 11.6 25.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CUU98387.1 - 0.56 8.1 1.9 0.69 7.8 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CUU98387.1 - 1.9 6.5 6.0 2.6 6.1 6.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MSP1_C PF07462.11 CUU98387.1 - 3.2 6.3 5.1 4.6 5.8 5.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4221 PF13970.6 CUU98388.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Arg_repressor_C PF02863.18 CUU98389.1 - 0.03 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Kelch_1 PF01344.25 CUU98390.1 - 3.3e-20 71.4 0.6 3.1e-09 36.3 0.0 4.5 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CUU98390.1 - 6.5e-14 51.6 0.1 1.4e-05 25.2 0.0 4.0 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CUU98390.1 - 5.4e-08 32.6 0.2 0.00016 21.6 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CUU98390.1 - 3.8e-07 30.0 0.1 0.00016 21.6 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CUU98390.1 - 4.7e-06 26.7 0.0 0.00026 21.2 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CUU98390.1 - 6.4e-06 25.9 0.0 0.0014 18.5 0.0 3.8 4 0 0 4 4 4 1 Kelch motif BTB PF00651.31 CUU98391.1 - 0.00015 21.9 0.0 0.00018 21.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain ESCRT-II PF05871.12 CUU98392.1 - 0.00042 20.6 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 2 1 ESCRT-II complex subunit GntR PF00392.21 CUU98392.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family EF-hand_1 PF00036.32 CUU98393.1 - 7.3e-15 53.3 1.2 2.9e-07 29.5 0.9 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CUU98393.1 - 2.3e-13 48.9 0.7 1.5e-05 24.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CUU98393.1 - 2e-11 42.8 2.3 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CUU98393.1 - 1.5e-09 38.2 0.9 3.6e-09 37.0 0.9 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CUU98393.1 - 1.9e-06 27.6 0.3 0.046 13.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CUU98393.1 - 0.00023 21.1 0.2 0.00025 20.9 0.2 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CUU98393.1 - 0.0035 17.6 0.2 2.7 8.3 0.0 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CUU98393.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain DEAD PF00270.29 CUU98405.1 - 8.5e-41 139.6 0.2 1.5e-40 138.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CUU98405.1 - 4e-32 110.9 0.3 1e-30 106.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CUU98405.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CUU98405.1 - 5.2e-05 23.3 0.2 0.00022 21.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CUU98405.1 - 8e-05 23.0 1.5 0.0026 18.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 CUU98405.1 - 0.00074 18.4 0.4 0.52 9.0 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 CUU98405.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 CUU98405.1 - 0.0095 16.2 0.2 0.049 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CUU98405.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 CUU98405.1 - 0.057 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PhoH PF02562.16 CUU98405.1 - 0.18 11.2 1.9 0.76 9.2 1.9 2.0 1 1 0 1 1 1 0 PhoH-like protein RRM_1 PF00076.22 CUU98409.1 - 2.8e-16 59.1 0.0 5.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CUU98409.1 - 6.2e-07 29.5 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif DUF1751 PF08551.10 CUU98411.1 - 1.6e-13 51.0 7.7 1.6e-13 51.0 7.7 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CUU98411.1 - 0.14 12.1 13.6 0.3 11.1 13.6 1.5 1 0 0 1 1 1 0 Rhomboid family MAS20 PF02064.15 CUU98412.1 - 0.031 14.4 0.7 0.031 14.4 0.7 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3391 PF11871.8 CUU98412.1 - 0.94 10.0 5.6 0.95 10.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Cystatin PF00031.21 CUU98413.1 - 1.7e-10 41.0 0.0 2.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 CUU98413.1 - 0.023 15.0 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor PilN PF05137.13 CUU98413.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) MRP-S23 PF10484.9 CUU98414.1 - 1.3e-05 25.5 0.3 0.0033 17.7 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 ABC_membrane PF00664.23 CUU98415.1 - 5e-06 26.4 3.9 6e-06 26.1 3.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region TMEM141 PF15110.6 CUU98415.1 - 0.064 13.8 1.0 0.1 13.2 0.2 1.7 2 0 0 2 2 2 0 TMEM141 protein family Pribosyltran PF00156.27 CUU98416.1 - 1.7e-21 76.4 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CUU98416.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Rad51 PF08423.11 CUU98421.1 - 3.3e-14 52.8 0.1 3.9e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Rad51 DUF3093 PF11292.8 CUU98423.1 - 0.011 16.0 0.2 2.5 8.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3093) nlz1 PF12402.8 CUU98423.1 - 0.14 12.7 0.0 5.9 7.4 0.0 2.1 1 1 1 2 2 2 0 NocA-like zinc-finger protein 1 DGF-1_4 PF11024.8 CUU98423.1 - 0.64 10.9 6.7 5 8.0 0.8 2.3 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 ubiquitin PF00240.23 CUU98424.1 - 2.8e-19 68.6 0.0 3.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CUU98424.1 - 2.5e-08 33.6 0.0 0.0073 16.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CUU98424.1 - 0.057 13.9 0.1 0.64 10.5 0.0 2.6 2 2 0 2 2 2 0 Ubiquitin-like domain PhnJ PF06007.11 CUU98424.1 - 0.074 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ubiquitin_4 PF18036.1 CUU98424.1 - 0.099 12.7 0.2 34 4.6 0.0 3.2 2 1 1 3 3 3 0 Ubiquitin-like domain HD PF01966.22 CUU98426.1 - 0.032 14.4 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 HD domain LIM PF00412.22 CUU98427.1 - 4.4e-12 46.0 2.2 6.7e-12 45.5 2.2 1.3 1 0 0 1 1 1 1 LIM domain DUF1284 PF06935.11 CUU98427.1 - 0.14 12.7 0.1 0.14 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Pkinase PF00069.25 CUU98428.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98428.1 - 0.003 16.9 0.0 0.0049 16.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU98429.1 - 2.3e-11 43.6 0.0 2.9e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98429.1 - 4.1e-08 32.8 0.0 4.8e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Epiglycanin_TR PF05647.11 CUU98431.1 - 0.19 11.7 2.7 0.3 11.0 2.7 1.3 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like DVL PF08137.12 CUU98431.1 - 0.33 10.9 0.7 0.51 10.2 0.7 1.3 1 0 0 1 1 1 0 DVL family Yippee-Mis18 PF03226.14 CUU98437.1 - 0.021 15.0 0.4 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RVT_1 PF00078.27 CUU98439.1 - 9.6e-13 48.1 0.1 1.3e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 CUU98443.1 - 1.3e-24 86.1 0.3 1.5e-24 85.9 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CUU98443.1 - 2.4e-06 27.3 0.1 2.9e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CUU98443.1 - 4.6e-06 26.6 0.1 5.3e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CUU98443.1 - 6.6e-05 23.3 0.1 0.00021 21.7 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CUU98443.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CUU98443.1 - 0.00091 19.5 0.5 0.011 16.0 0.2 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CUU98443.1 - 0.012 15.3 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 CUU98443.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 CUU98443.1 - 0.022 15.0 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Chordopox_A33R PF05966.12 CUU98444.1 - 0.032 13.5 0.5 0.035 13.4 0.5 1.0 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Synaptobrevin PF00957.21 CUU98444.1 - 0.056 13.2 0.4 5 7.0 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin HECT PF00632.25 CUU98445.1 - 5.8e-43 147.5 0.0 6.3e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ACI44 PF15270.6 CUU98447.1 - 0.00099 19.3 4.5 0.0016 18.6 4.5 1.2 1 0 0 1 1 1 1 Metallo-carboxypeptidase inhibitor Toxin_29 PF08116.11 CUU98447.1 - 0.0017 18.3 4.1 0.0025 17.7 4.1 1.3 1 0 0 1 1 1 1 PhTx neurotoxin family WAP PF00095.21 CUU98447.1 - 0.0075 16.6 5.3 0.0099 16.2 5.3 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Pro-rich PF15240.6 CUU98447.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.0 1 0 0 1 1 1 0 Proline-rich DX PF01666.17 CUU98447.1 - 0.02 15.3 3.3 0.027 14.9 3.3 1.3 1 0 0 1 1 1 0 DX module Dickkopf_N PF04706.12 CUU98447.1 - 0.025 15.1 4.3 0.04 14.4 4.3 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region TMEM215 PF15746.5 CUU98447.1 - 0.031 13.7 1.8 0.036 13.5 1.8 1.2 1 0 0 1 1 1 0 TMEM215 family DUF4834 PF16118.5 CUU98447.1 - 0.05 14.6 0.1 0.081 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM208_SND2 PF05620.11 CUU98447.1 - 0.069 12.9 0.6 0.11 12.3 0.6 1.3 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 PIP49_C PF12260.8 CUU98447.1 - 0.34 10.5 3.5 0.45 10.1 3.5 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 VESA1_N PF12785.7 CUU98447.1 - 0.83 8.5 9.2 0.94 8.4 9.2 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Hydrolase PF00702.26 CUU98448.1 - 0.0042 17.4 0.0 0.0045 17.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad51 PF08423.11 CUU98451.1 - 1.1e-19 70.7 0.0 1.3e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Rad51 Patatin PF01734.22 CUU98452.1 - 1.6e-07 31.8 0.2 2.5e-07 31.1 0.2 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Myc_N PF01056.18 CUU98452.1 - 0.47 10.3 7.9 0.22 11.4 1.8 2.4 2 1 1 3 3 3 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 CUU98452.1 - 0.96 9.9 4.9 2.9 8.3 4.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4530 PF15039.6 CUU98452.1 - 1.3 9.2 11.4 0.54 10.4 8.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) Dicty_REP PF05086.12 CUU98452.1 - 2.4 6.0 3.8 3.8 5.4 3.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Radial_spoke PF04712.12 CUU98452.1 - 2.6 6.9 9.7 4.3 6.2 9.7 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2384 PF09722.10 CUU98454.1 - 0.15 12.1 0.0 0.99 9.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) GST_C_3 PF14497.6 CUU98455.1 - 8.9e-09 35.4 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CUU98455.1 - 6.9e-06 26.2 0.0 8.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thioredoxin_13 PF18401.1 CUU98455.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain NS3 PF17530.2 CUU98455.1 - 0.041 13.5 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Non-structural protein NS3 FTH PF01827.27 CUU98455.1 - 0.075 12.8 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 FTH domain NUDE_C PF04880.13 CUU98456.1 - 10 6.6 7.3 13 6.2 7.3 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region tify PF06200.14 CUU98457.1 - 0.14 11.5 1.8 0.58 9.5 0.2 2.2 2 0 0 2 2 2 0 tify domain Pkinase_Tyr PF07714.17 CUU98459.1 - 0.0015 17.9 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU98459.1 - 0.015 14.6 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain p450 PF00067.22 CUU98460.1 - 2.2e-06 26.7 0.0 3.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SBF PF01758.16 CUU98462.1 - 1.3e-07 31.5 1.8 3.2e-07 30.2 1.8 1.7 1 0 0 1 1 1 1 Sodium Bile acid symporter family Cyt_bd_oxida_I PF01654.17 CUU98462.1 - 0.013 14.2 2.3 0.017 13.7 2.3 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I TssN PF17555.2 CUU98462.1 - 0.56 9.5 4.6 0.22 10.9 2.4 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF4834 PF16118.5 CUU98462.1 - 4.1 8.4 0.0 4.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TPR_19 PF14559.6 CUU98467.1 - 1.2e-08 35.4 8.8 0.00088 19.7 0.3 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CUU98467.1 - 2.9e-07 31.0 15.9 0.0029 18.2 1.5 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CUU98467.1 - 1.2e-06 28.9 11.9 0.073 13.9 0.9 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.17 CUU98467.1 - 0.0005 20.5 9.1 0.23 11.9 0.4 3.1 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 CUU98467.1 - 0.0007 18.9 2.0 0.25 10.5 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat KAR9 PF08580.10 CUU98467.1 - 0.043 12.4 0.1 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Synaptobrevin PF00957.21 CUU98467.1 - 0.058 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin Mad3_BUB1_I PF08311.12 CUU98467.1 - 0.06 13.3 0.6 8.2 6.4 0.0 2.5 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Suf PF05843.14 CUU98467.1 - 0.063 13.3 0.2 0.19 11.7 0.1 1.7 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_6 PF13174.6 CUU98467.1 - 0.078 13.6 7.8 44 5.0 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CUU98467.1 - 0.13 12.6 14.0 1.2 9.5 0.4 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CUU98467.1 - 0.13 12.3 4.0 36 4.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CUU98467.1 - 1.6 9.6 16.6 18 6.4 1.5 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CUU98467.1 - 3 8.2 11.2 1.7 8.9 1.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Kunitz_BPTI PF00014.23 CUU98468.1 - 4.9e-17 61.9 0.5 5.9e-17 61.6 0.5 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Pkinase_Tyr PF07714.17 CUU98474.1 - 1.9e-29 102.7 0.0 2.1e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU98474.1 - 4.1e-12 46.0 0.0 4.5e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain zf-RING_UBOX PF13445.6 CUU98476.1 - 9.6e-05 22.3 6.2 0.0063 16.5 2.8 2.4 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_6 PF14835.6 CUU98476.1 - 0.00091 19.1 1.1 0.0013 18.5 1.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CUU98476.1 - 0.00092 19.0 8.2 0.0015 18.4 8.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CUU98476.1 - 0.0042 17.0 8.9 0.0066 16.4 8.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CUU98476.1 - 0.013 15.3 9.7 0.024 14.5 9.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CUU98476.1 - 0.015 15.2 8.8 0.023 14.5 8.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CUU98476.1 - 0.026 14.8 10.3 0.045 14.1 10.3 1.4 1 0 0 1 1 1 0 Ring finger domain Phage_holin_3_6 PF07332.11 CUU98476.1 - 0.028 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Rad50_zn_hook PF04423.14 CUU98476.1 - 0.029 14.2 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 CUU98476.1 - 0.86 9.4 8.2 9.9 6.0 6.7 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 CUU98476.1 - 1.1 9.2 11.6 19 5.3 12.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4200 PF13863.6 CUU98477.1 - 9.5e-17 61.5 14.2 1.4e-16 61.0 14.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Forkhead PF00250.18 CUU98479.1 - 2.5e-27 94.9 0.6 4.3e-27 94.2 0.6 1.4 1 0 0 1 1 1 1 Forkhead domain Oxysterol_BP PF01237.18 CUU98482.1 - 4.7e-27 94.8 0.2 8.5e-27 93.9 0.2 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein Mannosyl_trans2 PF04188.13 CUU98482.1 - 0.061 12.6 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) CAP PF00188.26 CUU98486.1 - 1.9e-10 41.6 1.4 1.2e-08 35.9 0.9 2.2 1 1 1 2 2 2 2 Cysteine-rich secretory protein family RasGEF PF00617.19 CUU98487.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 RasGEF domain ABC_tran PF00005.27 CUU98489.1 - 5e-10 40.0 0.1 8.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CUU98489.1 - 0.00011 21.7 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain FKBP_N_2 PF18023.1 CUU98489.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal SDF PF00375.18 CUU98492.1 - 9.2e-08 31.5 0.2 1.3e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Myc_N PF01056.18 CUU98492.1 - 0.016 15.1 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Cadherin_tail PF15974.5 CUU98492.1 - 0.038 14.3 0.4 0.046 14.0 0.4 1.2 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region RNA_polI_A34 PF08208.11 CUU98492.1 - 0.052 13.6 9.7 0.07 13.2 9.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AFT PF08731.11 CUU98492.1 - 0.12 12.7 2.8 0.19 12.1 2.8 1.3 1 0 0 1 1 1 0 Transcription factor AFT DUF3824 PF12868.7 CUU98492.1 - 0.2 12.3 1.6 0.3 11.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AP3D1 PF06375.11 CUU98492.1 - 0.26 11.5 9.5 0.4 10.9 9.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ribosomal_60s PF00428.19 CUU98492.1 - 4.3 8.0 16.3 7.8 7.2 16.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 CUU98492.1 - 4.4 8.0 6.8 7.9 7.2 6.8 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DASH_Dad3 PF08656.10 CUU98493.1 - 0.045 13.8 0.9 0.25 11.5 0.5 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 ERp29 PF07749.12 CUU98493.1 - 0.051 14.5 1.9 0.051 14.5 1.9 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Got1 PF04178.12 CUU98495.1 - 0.00035 20.9 2.5 0.00043 20.7 2.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3784 PF12650.7 CUU98495.1 - 0.022 15.0 6.3 0.029 14.6 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Phage_holin_5_2 PF16079.5 CUU98495.1 - 0.072 13.4 4.1 0.068 13.5 3.1 1.5 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V DUF417 PF04224.12 CUU98495.1 - 0.13 11.8 3.8 0.18 11.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF2207 PF09972.9 CUU98495.1 - 0.27 9.9 3.5 0.33 9.7 3.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP1G1_PLM_MAT8 PF02038.16 CUU98495.1 - 7.4 6.1 6.4 0.49 9.9 0.7 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Ceramidase_alk PF04734.13 CUU98499.1 - 1.5e-39 136.0 0.1 1.6e-39 135.9 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Cadherin PF00028.17 CUU98501.1 - 0.0002 21.8 0.1 0.9 10.0 0.0 2.9 2 1 0 2 2 2 2 Cadherin domain zf-RVT PF13966.6 CUU98502.1 - 0.047 14.4 1.6 0.078 13.7 1.6 1.4 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase IQCJ-SCHIP1 PF15157.6 CUU98504.1 - 0.027 14.3 0.5 0.05 13.5 0.5 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Mito_fiss_reg PF05308.11 CUU98504.1 - 0.24 11.5 5.2 0.27 11.3 5.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2 PF00096.26 CUU98505.1 - 0.00013 22.2 1.3 0.00061 20.1 1.3 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU98505.1 - 0.0074 17.0 1.3 0.046 14.6 1.3 2.5 1 0 0 1 1 1 1 C2H2-type zinc finger SARA PF11409.8 CUU98506.1 - 0.36 11.1 1.3 27 5.1 0.0 2.3 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) Nop PF01798.18 CUU98507.1 - 0.048 13.1 0.2 0.056 12.9 0.2 1.2 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Phage_B PF02304.15 CUU98508.1 - 4e-83 275.5 2.7 4.4e-83 275.3 2.7 1.0 1 0 0 1 1 1 1 Scaffold protein B Prenyltrans PF00432.21 CUU98509.1 - 0.097 12.4 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat CEND1 PF15677.5 CUU98510.1 - 0.52 10.9 3.5 0.6 10.6 3.5 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Parvo_NS1 PF01057.17 CUU98512.1 - 1e-16 60.9 0.0 1.4e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.17 CUU98512.1 - 2.6e-07 29.9 0.0 3.4e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Papillomavirus helicase AAA PF00004.29 CUU98512.1 - 0.083 13.3 0.8 1.1 9.7 0.3 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CUU98512.1 - 0.13 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 CUU98514.1 - 1.8e-08 33.7 0.1 2.1e-08 33.5 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 CUU98514.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Nodulin-like NMN_transporter PF04973.12 CUU98514.1 - 0.1 12.5 3.4 3.6 7.5 1.3 2.1 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter UCH PF00443.29 CUU98516.1 - 1.7e-08 34.3 0.0 2e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Antimicrobial22 PF16047.5 CUU98516.1 - 0.054 13.4 0.7 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Endonuclease_5 PF04493.14 CUU98518.1 - 3.2e-06 27.0 0.0 3.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V Ribosomal_L5_C PF00673.21 CUU98524.1 - 0.032 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Phage_F PF02305.17 CUU98527.1 - 2e-44 152.2 0.0 2.2e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Capsid protein (F protein) NAD_binding_1 PF00175.21 CUU98531.1 - 1.6e-09 38.4 0.0 2.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CUU98531.1 - 0.00013 22.1 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CUU98531.1 - 0.0039 17.5 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ank_2 PF12796.7 CUU98532.1 - 9.1e-159 516.5 58.5 4.5e-18 65.6 1.2 11.9 1 1 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU98532.1 - 1.4e-146 475.1 54.1 3.7e-11 43.3 0.0 15.9 4 4 16 20 20 20 20 Ankyrin repeats (many copies) Ank PF00023.30 CUU98532.1 - 1.7e-132 426.6 58.2 2.1e-07 31.0 0.1 22.4 21 1 1 22 22 22 22 Ankyrin repeat Ank_5 PF13857.6 CUU98532.1 - 2.6e-119 387.7 44.6 6.5e-12 45.5 0.0 17.4 4 3 16 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU98532.1 - 9.2e-115 360.5 40.6 2.3e-06 27.5 0.0 23.2 23 0 0 23 23 23 21 Ankyrin repeat Imm_superinfect PF14373.6 CUU98532.1 - 0.14 12.1 0.3 29 4.7 0.0 4.2 5 0 0 5 5 5 0 Superinfection immunity protein DUF3447 PF11929.8 CUU98532.1 - 0.15 12.1 0.0 39 4.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) VWA_3_C PF18571.1 CUU98532.1 - 1.3 9.0 5.1 42 4.1 0.0 4.8 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain UPA_2 PF17809.1 CUU98533.1 - 6.3e-45 152.2 0.1 5.9e-44 149.1 0.1 2.3 1 1 0 1 1 1 1 UPA domain ZU5 PF00791.20 CUU98533.1 - 3.3e-37 126.8 0.6 5.6e-27 94.0 0.0 2.7 2 0 0 2 2 2 2 ZU5 domain Death PF00531.22 CUU98533.1 - 2e-05 24.6 0.1 0.00026 21.1 0.0 2.4 1 1 1 2 2 2 1 Death domain WAPL PF07814.13 CUU98534.1 - 1.7e-39 135.7 1.6 1.2e-38 132.9 1.6 2.1 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin TFIIA PF03153.13 CUU98534.1 - 0.00012 22.2 9.9 0.00012 22.2 9.9 3.9 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Packaging_FI PF14000.6 CUU98534.1 - 0.0025 18.3 0.0 0.0025 18.3 0.0 3.1 3 0 0 3 3 3 1 DNA packaging protein FI Ham1p_like PF01725.16 CUU98535.1 - 5.2e-52 176.5 0.0 7.1e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Ham1 family PHD PF00628.29 CUU98535.1 - 1.3e-05 25.0 4.7 2.2e-05 24.3 4.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 CUU98535.1 - 0.00076 19.5 5.0 0.0014 18.6 5.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CUU98535.1 - 0.027 14.0 3.2 0.071 12.7 3.2 1.7 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CUU98535.1 - 0.13 12.1 0.3 0.13 12.1 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Toxin_27 PF08099.11 CUU98536.1 - 0.045 13.9 0.4 0.086 13.0 0.4 1.5 1 0 0 1 1 1 0 Scorpion calcine family DUF2732 PF10809.8 CUU98538.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) HTH_48 PF17906.1 CUU98539.1 - 0.0057 16.7 0.1 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 HTH domain in Mos1 transposase DUF2459 PF09601.10 CUU98539.1 - 0.076 12.8 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) Rhodanese PF00581.20 CUU98541.1 - 2.5e-08 34.4 0.0 1.4e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain DUF977 PF06163.11 CUU98542.1 - 0.095 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Cadherin PF00028.17 CUU98543.1 - 3.8e-05 24.0 0.0 0.00055 20.3 0.0 2.3 2 0 0 2 2 2 1 Cadherin domain Cadherin PF00028.17 CUU98544.1 - 1.2e-25 89.7 0.8 1.2e-11 44.9 0.0 3.6 3 1 0 3 3 3 3 Cadherin domain Ureidogly_lyase PF04115.12 CUU98544.1 - 0.096 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Ureidoglycolate lyase Kunitz_BPTI PF00014.23 CUU98547.1 - 1.4e-09 38.0 0.0 1.7e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TcdB_toxin_midN PF12256.8 CUU98548.1 - 0.037 13.4 0.5 0.043 13.2 0.5 1.0 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Pkinase PF00069.25 CUU98549.1 - 5.5e-38 130.8 0.0 1.7e-37 129.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98549.1 - 1.1e-12 47.8 0.0 3.2e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CUU98549.1 - 2.2e-06 27.2 0.1 9e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 CUU98549.1 - 4e-06 27.3 0.2 0.0025 18.3 0.1 2.7 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 CUU98549.1 - 0.0016 17.8 0.0 0.0056 16.1 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CUU98549.1 - 0.0066 16.4 0.0 0.0066 16.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Spc7 PF08317.11 CUU98549.1 - 0.035 13.0 55.5 0.0081 15.1 8.8 3.6 1 1 1 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 CUU98549.1 - 0.049 13.7 49.3 0.022 14.9 3.8 4.6 3 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding Seadorna_VP7 PF07387.11 CUU98549.1 - 0.052 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 C1_1 PF00130.22 CUU98549.1 - 0.068 13.1 4.0 0.14 12.1 4.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1319 PF07028.11 CUU98549.1 - 0.091 13.0 18.4 2.6 8.3 0.7 4.7 2 2 1 4 4 4 0 Protein of unknown function (DUF1319) TolA_bind_tri PF16331.5 CUU98549.1 - 0.85 9.7 26.5 0.25 11.5 4.8 4.2 3 1 0 3 3 3 0 TolA binding protein trimerisation ATG16 PF08614.11 CUU98549.1 - 1.1 9.5 63.5 0.83 9.8 8.1 4.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CUU98549.1 - 1.9 7.8 51.0 0.29 10.5 6.7 3.7 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 CUU98549.1 - 5.8 6.4 48.0 1.1 8.8 2.5 3.5 2 1 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF4618 PF15397.6 CUU98549.1 - 6.1 6.2 40.3 0.023 14.1 3.5 4.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) DarA_C PF18789.1 CUU98550.1 - 0.2 12.0 0.0 0.62 10.4 0.0 1.7 2 0 0 2 2 2 0 Defence against restriction A C-terminal MORN PF02493.20 CUU98553.1 - 8.6e-28 94.6 39.1 9.4e-06 25.2 0.3 6.9 7 0 0 7 7 7 6 MORN repeat Ribosomal_60s PF00428.19 CUU98557.1 - 1.4e-21 76.9 8.0 1.7e-21 76.6 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 CUU98557.1 - 0.0054 16.8 4.2 0.0072 16.4 4.2 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Phage_holin_6_1 PF09682.10 CUU98557.1 - 0.13 12.6 0.5 1.6 9.2 0.0 2.0 1 1 1 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DEAD PF00270.29 CUU98559.1 - 8.5e-41 139.6 0.2 1.5e-40 138.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CUU98559.1 - 4e-32 110.9 0.3 1e-30 106.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CUU98559.1 - 5.8e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CUU98559.1 - 5.2e-05 23.3 0.2 0.00022 21.3 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CUU98559.1 - 8e-05 23.0 1.5 0.0026 18.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 CUU98559.1 - 0.00074 18.4 0.4 0.52 9.0 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 CUU98559.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 CUU98559.1 - 0.0095 16.2 0.2 0.049 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CUU98559.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 CUU98559.1 - 0.057 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PhoH PF02562.16 CUU98559.1 - 0.18 11.2 1.9 0.76 9.2 1.9 2.0 1 1 0 1 1 1 0 PhoH-like protein Actin PF00022.19 CUU98560.1 - 5.9e-105 351.2 0.0 7.1e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CUU98560.1 - 0.061 12.1 0.0 2.9 6.6 0.0 2.4 2 1 0 2 2 2 0 MreB/Mbl protein BON PF04972.17 CUU98560.1 - 0.089 13.1 0.1 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 BON domain Cpn60_TCP1 PF00118.24 CUU98562.1 - 7.2e-85 285.5 11.3 2.9e-84 283.5 11.3 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MIP PF00230.20 CUU98563.1 - 2.5e-33 115.7 11.7 3.1e-33 115.4 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3397 PF11877.8 CUU98563.1 - 0.19 11.9 2.5 0.23 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) MutS_II PF05188.17 CUU98564.1 - 0.098 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 MutS domain II Collagen PF01391.18 CUU98565.1 - 7.7e-162 525.2 664.0 1.6e-09 37.3 34.6 20.1 2 2 10 12 12 12 9 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CUU98565.1 - 3.1e-36 124.9 0.0 4.6e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Metallophos PF00149.28 CUU98567.1 - 3e-31 109.5 0.1 4.8e-31 108.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FYVE PF01363.21 CUU98567.1 - 2.1e-15 56.6 13.3 4.5e-15 55.5 13.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CUU98567.1 - 0.93 9.7 7.0 1.7 8.9 7.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Ras PF00071.22 CUU98570.1 - 3.4e-52 176.3 0.3 5.6e-52 175.6 0.3 1.3 1 0 0 1 1 1 1 Ras family Pkinase PF00069.25 CUU98570.1 - 1.9e-27 96.3 0.0 3.2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Roc PF08477.13 CUU98570.1 - 7.1e-16 58.5 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 CUU98570.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.21 CUU98570.1 - 4e-06 26.4 0.1 6.7e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CUU98570.1 - 2.3e-05 24.0 0.1 4.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CUU98570.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CUU98570.1 - 0.064 13.2 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SapB_2 PF03489.17 CUU98572.1 - 6.8e-35 118.9 32.7 1.1e-11 44.6 1.4 7.2 7 0 0 7 7 7 5 Saposin-like type B, region 2 SapB_1 PF05184.15 CUU98572.1 - 2e-22 78.8 33.5 8.2e-12 44.9 6.1 7.2 6 0 0 6 6 6 4 Saposin-like type B, region 1 SapA PF02199.15 CUU98572.1 - 2.8e-11 43.5 17.1 2e-09 37.6 1.4 4.0 4 0 0 4 4 4 2 Saposin A-type domain Speriolin_C PF15059.6 CUU98572.1 - 0.11 12.6 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Speriolin C-terminus DUF3908 PF13048.6 CUU98572.1 - 0.35 11.1 5.4 1.5 9.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3908) zf-Mss51 PF13824.6 CUU98572.1 - 2.5 8.3 6.9 12 6.1 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Pkinase PF00069.25 CUU98573.1 - 1.1e-59 202.0 0.1 2.4e-59 200.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98573.1 - 2.6e-28 99.0 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CUU98573.1 - 2.1e-05 24.0 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CUU98573.1 - 0.00035 20.0 0.2 0.0006 19.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CUU98573.1 - 0.00065 19.3 0.3 0.0015 18.2 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CUU98573.1 - 0.0013 17.6 0.1 0.0013 17.6 0.1 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CUU98573.1 - 0.0052 16.7 0.1 0.026 14.5 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CUU98573.1 - 0.03 13.9 0.2 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Yip1 PF04893.17 CUU98574.1 - 1e-13 51.4 4.7 1.5e-13 50.9 4.6 1.3 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 CUU98574.1 - 2.1e-10 40.6 4.1 5.9e-08 32.5 4.1 2.2 1 1 0 1 1 1 1 YIF1 DUF4149 PF13664.6 CUU98574.1 - 0.29 11.5 8.0 0.095 13.0 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) HKR_ArcB_TM PF18415.1 CUU98574.1 - 6.1 7.7 6.5 1.1 10.0 1.5 2.3 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain FAR1 PF03101.15 CUU98575.1 - 6.7e-07 29.9 3.0 2.9e-05 24.7 0.5 2.7 2 0 0 2 2 2 2 FAR1 DNA-binding domain NID PF07292.13 CUU98575.1 - 0.18 12.5 0.6 0.49 11.1 0.1 1.9 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) TPD52 PF04201.15 CUU98575.1 - 0.37 10.4 1.4 5.1 6.7 0.1 2.6 2 0 0 2 2 2 0 Tumour protein D52 family FERM_f0 PF16511.5 CUU98578.1 - 1.5e-30 105.3 0.0 7.9e-30 103.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 CUU98578.1 - 1.2e-08 34.8 0.4 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 2 FERM N-terminal domain ubiquitin PF00240.23 CUU98578.1 - 0.001 18.8 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family Tetraspanin PF00335.20 CUU98579.1 - 9.7e-16 58.2 15.7 1.3e-15 57.8 15.7 1.2 1 0 0 1 1 1 1 Tetraspanin family G0-G1_switch_2 PF15103.6 CUU98579.1 - 0.0036 17.7 0.2 0.0062 16.9 0.2 1.3 1 0 0 1 1 1 1 G0/G1 switch protein 2 Baculo_11_kDa PF06143.11 CUU98579.1 - 0.34 10.5 5.2 0.11 12.1 1.4 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family PALP PF00291.25 CUU98580.1 - 2.4e-11 43.6 0.0 3.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Piwi PF02171.17 CUU98581.1 - 1.2e-15 57.5 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CUU98581.1 - 1.6e-13 50.7 0.1 3.2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CUU98581.1 - 0.00025 21.3 0.2 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 CUU98581.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 CUU98581.1 - 0.01 16.5 0.0 0.023 15.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute Pkinase PF00069.25 CUU98583.1 - 1.8e-37 129.2 0.7 5.9e-37 127.5 0.7 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98583.1 - 2.4e-21 76.2 0.6 5.9e-21 74.9 0.6 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CUU98583.1 - 0.00011 22.3 0.1 0.00023 21.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CUU98583.1 - 0.0018 17.7 0.1 0.0034 16.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CUU98583.1 - 0.0057 16.3 0.2 0.029 13.9 0.2 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CUU98583.1 - 0.017 14.1 0.2 0.038 12.9 0.0 1.5 1 1 0 2 2 2 0 Haspin like kinase domain Vta1_C PF18097.1 CUU98583.1 - 0.19 11.4 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Vta1 C-terminal domain Zip PF02535.22 CUU98584.1 - 6.1e-48 163.7 10.8 6.1e-48 163.7 10.8 2.6 1 1 1 2 2 2 1 ZIP Zinc transporter Surfac_D-trimer PF09006.11 CUU98585.1 - 0.19 11.6 0.3 0.42 10.6 0.3 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Dynein_light PF01221.18 CUU98587.1 - 2.4e-39 133.5 5.7 4.5e-23 81.4 0.7 2.1 2 0 0 2 2 2 2 Dynein light chain type 1 DUF2634 PF10934.8 CUU98587.1 - 3.4e-05 23.9 0.5 0.34 11.0 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2634) Mso1_Sec1_bdg PF14475.6 CUU98587.1 - 0.0053 16.3 0.3 4.1 7.1 0.0 2.5 2 0 0 2 2 2 2 Sec1-binding region of Mso1 DUF5473 PF17567.2 CUU98587.1 - 0.021 15.1 0.0 11 6.4 0.0 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5473) Pilin_N PF07790.11 CUU98587.1 - 0.051 14.5 0.4 0.78 10.7 0.1 2.4 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal YlmH_RBD PF17774.1 CUU98587.1 - 0.11 12.8 1.2 10 6.5 0.0 3.4 2 2 0 3 3 3 0 Putative RNA-binding domain in YlmH Rap1a PF18602.1 CUU98587.1 - 0.11 12.8 1.0 48 4.4 0.0 3.4 4 0 0 4 4 4 0 Rap1a immunity proteins DUF3173 PF11372.8 CUU98587.1 - 0.12 12.2 0.1 25 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) HTH_ParB PF17762.1 CUU98587.1 - 0.45 10.3 4.9 13 5.6 0.1 3.1 4 0 0 4 4 4 0 HTH domain found in ParB protein Limkain-b1 PF11608.8 CUU98588.1 - 0.019 15.0 0.3 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 DUF3237 PF11578.8 CUU98588.1 - 0.13 12.1 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) gpUL132 PF11359.8 CUU98588.1 - 5.5 6.5 10.3 11 5.5 1.7 2.3 2 0 0 2 2 2 0 Glycoprotein UL132 DUF3237 PF11578.8 CUU98589.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) C2 PF00168.30 CUU98591.1 - 9.8e-30 102.9 0.0 4.7e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain PDZ_6 PF17820.1 CUU98591.1 - 1.4e-12 47.3 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CUU98591.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FYVE_2 PF02318.16 CUU98591.1 - 0.0046 17.2 6.5 0.0046 17.2 6.5 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger HSP70 PF00012.20 CUU98592.1 - 4.5e-130 434.7 9.8 2.3e-94 316.8 5.5 3.1 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CUU98592.1 - 0.00068 18.5 0.1 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Ccdc124 PF06244.12 CUU98593.1 - 3.7e-28 98.7 13.1 2.5e-27 95.9 13.1 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CUU98593.1 - 2.6e-05 24.5 1.3 2.6e-05 24.5 1.3 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box DUF4407 PF14362.6 CUU98593.1 - 0.085 12.2 3.6 0.12 11.8 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAP2 PF01569.21 CUU98596.1 - 1.3e-10 41.2 2.5 1.3e-10 41.2 2.5 2.3 2 1 0 2 2 2 1 PAP2 superfamily AtpR PF12966.7 CUU98596.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.8 3 0 0 3 3 3 0 N-ATPase, AtpR subunit DUF456 PF04306.13 CUU98596.1 - 1.5 9.1 10.0 2.8 8.2 6.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF456) SpoU_methylase PF00588.19 CUU98597.1 - 3.5e-22 79.1 0.0 6.6e-21 75.0 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family Neur_chan_LBD PF02931.23 CUU98598.1 - 1.4e-51 175.1 3.0 5e-51 173.2 3.0 2.0 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CUU98598.1 - 2.4e-36 126.0 4.2 4.8e-36 125.0 4.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 CUU98598.1 - 3.6e-14 52.9 13.7 0.042 14.7 0.1 8.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CUU98598.1 - 0.0013 17.6 0.1 0.082 11.6 0.0 3.0 2 1 1 3 3 3 1 Nup133 N terminal like DUF1616 PF07760.11 CUU98598.1 - 0.61 9.4 3.2 1 8.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) ETRAMP PF09716.10 CUU98600.1 - 0.016 15.3 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) LRR_6 PF13516.6 CUU98603.1 - 1e-17 62.6 8.3 4.7e-05 23.1 0.1 7.7 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 CUU98603.1 - 1.3e-05 25.5 18.6 0.0026 18.1 1.1 5.8 3 2 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CUU98603.1 - 0.00022 21.4 13.1 30 5.7 0.0 7.6 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 CUU98603.1 - 0.013 15.2 16.0 13 5.7 2.3 6.7 4 2 1 5 5 5 0 Leucine rich repeat LRR_2 PF07723.13 CUU98603.1 - 0.027 15.2 1.9 84 4.1 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Sm_like PF16243.5 CUU98603.1 - 0.084 13.0 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Sm_like domain DivIC PF04977.15 CUU98603.1 - 0.84 9.5 3.2 1.7 8.5 3.2 1.5 1 0 0 1 1 1 0 Septum formation initiator SpoIIIAH PF12685.7 CUU98603.1 - 2.1 8.1 6.8 4.3 7.1 6.8 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Transket_pyr PF02779.24 CUU98604.1 - 1.4e-43 148.6 0.1 2.2e-43 148.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CUU98604.1 - 8.6e-39 132.2 0.0 1.6e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CUU98604.1 - 0.0013 19.0 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Gln-synt_N_2 PF16952.5 CUU98605.1 - 0.00027 20.7 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Glutamine synthetase N-terminal domain CmlA_N PF18456.1 CUU98605.1 - 0.046 13.0 3.9 3.3 6.9 0.3 2.2 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain DUF4796 PF16044.5 CUU98605.1 - 0.73 9.4 2.9 23 4.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) COA2 PF17051.5 CUU98605.1 - 7.9 6.6 11.4 1e+02 3.1 1.0 4.6 4 0 0 4 4 4 0 Cytochrome C oxidase assembly factor 2 SelP_N PF04592.14 CUU98606.1 - 5.2 6.4 18.6 5.3 6.4 5.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IPPT PF01715.17 CUU98607.1 - 1.1e-46 159.5 0.0 3.5e-46 157.8 0.0 1.8 2 0 0 2 2 2 1 IPP transferase LETM1 PF07766.13 CUU98607.1 - 7.5e-32 110.7 0.0 4.6e-25 88.5 0.0 2.2 2 0 0 2 2 2 2 LETM1-like protein zf-C2H2_2 PF12756.7 CUU98607.1 - 1e-06 29.0 0.0 0.086 13.2 0.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) IPT PF01745.16 CUU98607.1 - 5.3e-06 26.0 0.0 8.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 CUU98607.1 - 0.00031 20.9 0.8 1.3 9.4 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 CUU98607.1 - 0.00079 19.3 0.8 1.7 8.4 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) AAA_33 PF13671.6 CUU98607.1 - 0.0022 18.2 0.0 0.0076 16.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain zf-DBF PF07535.12 CUU98607.1 - 0.0029 17.7 0.3 4.5 7.5 0.0 2.7 2 0 0 2 2 2 2 DBF zinc finger AAA_18 PF13238.6 CUU98607.1 - 0.0091 16.5 0.0 0.043 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CUU98607.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 CUU98607.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CUU98607.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Albumin_I_a PF16720.5 CUU98607.1 - 0.036 14.0 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 Albumin I chain a CEP44 PF15007.6 CUU98607.1 - 0.048 13.8 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 Sod_Fe_N PF00081.22 CUU98607.1 - 0.062 13.8 0.0 27 5.3 0.0 2.7 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain AAA PF00004.29 CUU98607.1 - 0.068 13.6 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PWI PF01480.17 CUU98607.1 - 0.071 13.4 0.0 57 4.1 0.0 3.4 3 0 0 3 3 3 0 PWI domain CbiA PF01656.23 CUU98607.1 - 0.1 12.6 0.0 1.5 8.9 0.0 2.9 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 CUU98607.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AKAP95 PF04988.12 CUU98607.1 - 0.11 12.7 3.4 9.8 6.4 0.1 2.7 3 0 0 3 3 2 0 A-kinase anchoring protein 95 (AKAP95) RNA_helicase PF00910.22 CUU98607.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SelR PF01641.18 CUU98607.1 - 0.14 12.2 1.8 16 5.6 0.1 2.3 2 0 0 2 2 2 0 SelR domain Connexin40_C PF16791.5 CUU98607.1 - 0.18 13.1 0.4 50 5.2 0.1 2.6 2 0 0 2 2 2 0 Connexin 40 C-terminal domain Ribophorin_I PF04597.14 CUU98608.1 - 3.5e-111 372.5 2.5 3.5e-111 372.5 2.5 1.8 2 0 0 2 2 2 1 Ribophorin I DNA_repr_REX1B PF14966.6 CUU98608.1 - 5.9e-06 26.9 0.6 1.3e-05 25.7 0.6 1.6 1 0 0 1 1 1 1 DNA repair REX1-B T3SSipB PF16535.5 CUU98608.1 - 0.0028 18.1 1.5 0.0048 17.4 1.5 1.3 1 0 0 1 1 1 1 Type III cell invasion protein SipB ZapB PF06005.12 CUU98608.1 - 0.004 17.6 3.6 0.02 15.4 3.6 2.2 1 1 0 1 1 1 1 Cell division protein ZapB FapA PF03961.13 CUU98608.1 - 0.049 12.2 0.6 0.076 11.6 0.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4315 PF14193.6 CUU98608.1 - 0.085 12.9 0.1 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF1027 PF06265.11 CUU98608.1 - 0.11 12.5 1.3 0.29 11.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) K-box PF01486.17 CUU98608.1 - 0.15 12.2 2.7 0.18 12.0 0.4 2.1 2 0 0 2 2 2 0 K-box region Seryl_tRNA_N PF02403.22 CUU98608.1 - 0.56 10.5 4.2 1.9 8.7 0.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribophorin_I PF04597.14 CUU98609.1 - 3.5e-111 372.5 2.5 3.5e-111 372.5 2.5 1.8 2 0 0 2 2 2 1 Ribophorin I DNA_repr_REX1B PF14966.6 CUU98609.1 - 5.9e-06 26.9 0.6 1.3e-05 25.7 0.6 1.6 1 0 0 1 1 1 1 DNA repair REX1-B T3SSipB PF16535.5 CUU98609.1 - 0.0028 18.1 1.5 0.0048 17.4 1.5 1.3 1 0 0 1 1 1 1 Type III cell invasion protein SipB ZapB PF06005.12 CUU98609.1 - 0.004 17.6 3.6 0.02 15.4 3.6 2.2 1 1 0 1 1 1 1 Cell division protein ZapB FapA PF03961.13 CUU98609.1 - 0.049 12.2 0.6 0.076 11.6 0.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4315 PF14193.6 CUU98609.1 - 0.085 12.9 0.1 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF1027 PF06265.11 CUU98609.1 - 0.11 12.5 1.3 0.29 11.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) K-box PF01486.17 CUU98609.1 - 0.15 12.2 2.7 0.18 12.0 0.4 2.1 2 0 0 2 2 2 0 K-box region Seryl_tRNA_N PF02403.22 CUU98609.1 - 0.56 10.5 4.2 1.9 8.7 0.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AA_permease_2 PF13520.6 CUU98610.1 - 4.1e-43 147.8 34.9 4.1e-43 147.8 34.9 2.5 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CUU98610.1 - 3e-24 85.5 35.2 3e-24 85.5 35.2 2.2 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 CUU98610.1 - 8.5e-18 64.2 8.0 8.5e-18 64.2 8.0 4.0 4 0 0 4 4 4 2 C-terminus of AA_permease DUF4464 PF14713.6 CUU98611.1 - 1.6e-62 211.0 0.2 2e-62 210.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Fz PF01392.22 CUU98612.1 - 6.7e-06 26.7 0.1 8.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Fz domain RFX5_N PF18326.1 CUU98616.1 - 0.0063 16.3 0.5 0.025 14.3 0.4 2.1 2 0 0 2 2 2 1 RFX5 N-terminal domain Toxin_10 PF05431.11 CUU98616.1 - 0.15 11.5 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF3781 PF12636.7 CUU98617.1 - 0.12 12.3 0.2 0.34 10.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3781) LRRNT PF01462.18 CUU98618.1 - 4.9e-08 32.4 1.6 7.4e-08 31.9 1.6 1.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain ART PF01129.18 CUU98618.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Ion_trans PF00520.31 CUU98620.1 - 2.8e-59 200.3 19.4 4.1e-59 199.8 19.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ca_chan_IQ PF08763.11 CUU98620.1 - 7.8e-30 102.9 0.0 2.1e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CUU98620.1 - 1.8e-27 94.8 0.0 3.7e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CUU98620.1 - 5e-07 28.7 12.2 6.4e-05 21.8 5.2 2.2 1 1 1 2 2 2 2 Polycystin cation channel UL17 PF17640.2 CUU98620.1 - 0.083 12.9 2.2 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized UL17 SKG6 PF08693.10 CUU98621.1 - 1.6e-05 24.2 2.8 1.6e-05 24.2 2.8 1.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 CUU98621.1 - 0.0011 18.7 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 CUU98621.1 - 0.0027 17.7 0.3 0.0037 17.3 0.3 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF4010 PF13194.6 CUU98621.1 - 0.0097 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) EphA2_TM PF14575.6 CUU98621.1 - 0.066 14.1 0.0 0.078 13.9 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CUU98621.1 - 0.082 12.8 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Gram_pos_anchor PF00746.21 CUU98621.1 - 0.13 12.3 4.2 0.69 9.9 4.2 2.0 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF4381 PF14316.6 CUU98621.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CD34_antigen PF06365.12 CUU98621.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family Stevor PF17410.2 CUU98621.1 - 0.26 10.8 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FeoB_associated PF12669.7 CUU98621.1 - 1.8 9.0 3.7 2.5 8.5 3.7 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein B56 PF01603.20 CUU98622.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 CUU98624.1 - 3.8e-70 236.3 0.0 5.3e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98624.1 - 1.6e-39 135.7 0.0 2.5e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CUU98624.1 - 9.2e-06 25.2 0.2 2.9e-05 23.5 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CUU98624.1 - 0.00051 19.4 0.5 0.001 18.5 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M22 PF00814.25 CUU98624.1 - 0.12 12.1 0.3 2.4 7.8 0.0 2.3 2 1 0 2 2 2 0 Glycoprotease family TED PF08341.11 CUU98625.1 - 0.15 12.5 0.0 1.3 9.5 0.0 1.9 1 1 0 2 2 2 0 Thioester domain LRR_8 PF13855.6 CUU98626.1 - 1.4e-17 63.2 8.5 7.9e-08 31.9 0.0 4.7 4 0 0 4 4 4 2 Leucine rich repeat RRM_1 PF00076.22 CUU98626.1 - 7.7e-14 51.3 0.2 1.6e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP_bind_3 PF01171.20 CUU98626.1 - 1.7e-13 50.8 0.0 3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CUU98626.1 - 2.5e-13 49.3 1.8 2.5e-13 49.3 1.8 3.9 4 0 0 4 4 4 1 Zinc-ribbon LRR_4 PF12799.7 CUU98626.1 - 1.1e-09 38.4 12.9 6.2e-05 23.3 0.2 5.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CUU98626.1 - 0.00037 20.6 9.8 24 6.0 0.0 7.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_5 PF13306.6 CUU98626.1 - 0.0029 17.6 1.5 0.74 9.8 0.0 4.2 3 2 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CUU98626.1 - 0.029 14.4 3.9 2 8.7 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat TF_Zn_Ribbon PF08271.12 CUU98626.1 - 7.1 6.2 11.6 0.049 13.2 0.7 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding Cast PF10174.9 CUU98627.1 - 5.4e-96 322.5 158.5 9.6e-92 308.5 127.4 11.0 3 3 6 9 9 9 6 RIM-binding protein of the cytomatrix active zone Tropomyosin PF00261.20 CUU98627.1 - 0.00025 20.5 41.2 0.00025 20.5 41.2 17.6 7 4 5 14 14 14 3 Tropomyosin HrpB7 PF09486.10 CUU98627.1 - 0.0051 17.2 1.4 0.0051 17.2 1.4 20.5 5 5 12 20 20 20 3 Bacterial type III secretion protein (HrpB7) CM1 PF03026.15 CUU98628.1 - 0.0045 16.4 0.1 0.0045 16.4 0.1 1.0 1 0 0 1 1 1 1 Influenza C virus M1 protein HSL_N PF06350.12 CUU98630.1 - 7e-46 156.6 0.6 1.6e-36 125.8 0.1 2.1 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus TSKS PF15358.6 CUU98630.1 - 0.85 7.9 2.4 0.56 8.5 0.1 1.7 2 0 0 2 2 2 0 Testis-specific serine kinase substrate 7tm_1 PF00001.21 CUU98631.1 - 2.4e-15 56.6 4.6 3e-15 56.3 4.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DcuC PF03606.15 CUU98631.1 - 1.9e-05 23.3 0.6 2.6e-05 22.9 0.6 1.1 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier STE3 PF02076.15 CUU98631.1 - 7.9e-05 22.0 3.5 0.00012 21.4 3.5 1.2 1 0 0 1 1 1 1 Pheromone A receptor 7TM_GPCR_Srsx PF10320.9 CUU98631.1 - 0.0023 17.3 3.2 0.0032 16.9 3.2 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4079 PF13301.6 CUU98631.1 - 0.0069 16.5 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) DUF420 PF04238.12 CUU98631.1 - 0.0083 16.4 1.6 0.012 15.9 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF420) Frizzled PF01534.17 CUU98631.1 - 0.021 13.9 3.6 0.052 12.6 3.5 1.7 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF3382 PF11862.8 CUU98631.1 - 0.03 14.6 2.3 0.91 9.8 2.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) CitMHS_2 PF16980.5 CUU98631.1 - 0.033 12.8 0.3 0.042 12.5 0.3 1.1 1 0 0 1 1 1 0 Putative citrate transport Sm_multidrug_ex PF06695.11 CUU98631.1 - 0.039 14.6 0.2 0.075 13.7 0.2 1.4 1 0 0 1 1 1 0 Putative small multi-drug export protein Orf78 PF06024.12 CUU98631.1 - 4.6 7.6 6.0 4.8 7.5 0.2 2.4 1 1 1 2 2 2 0 Orf78 (ac78) Tetraspanin PF00335.20 CUU98633.1 - 9.4e-19 68.0 15.4 1.7e-14 54.1 3.6 2.0 1 1 1 2 2 2 2 Tetraspanin family YpmT PF17431.2 CUU98633.1 - 2e-06 27.8 7.1 0.0028 17.7 0.3 3.1 3 0 0 3 3 3 2 Uncharacterized YmpT-like CitMHS PF03600.16 CUU98633.1 - 0.0049 16.1 2.8 0.0066 15.7 2.8 1.1 1 0 0 1 1 1 1 Citrate transporter Cas1_AcylT PF07779.12 CUU98633.1 - 0.0084 15.1 1.9 0.48 9.3 0.1 2.1 2 0 0 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p CcmH PF03918.14 CUU98633.1 - 0.12 11.6 2.6 0.78 9.0 0.1 2.8 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Claudin_2 PF13903.6 CUU98633.1 - 0.14 11.9 0.1 0.14 11.9 0.1 3.0 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction PTPS_related PF10131.9 CUU98633.1 - 0.2 10.0 5.2 0.38 9.0 0.4 2.1 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein TMCCDC2 PF15844.5 CUU98633.1 - 0.3 11.0 3.3 0.35 10.8 0.3 2.2 2 1 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 LPG_synthase_TM PF03706.13 CUU98633.1 - 0.31 10.5 11.9 0.15 11.6 4.9 2.4 2 1 1 3 3 3 0 Lysylphosphatidylglycerol synthase TM region DUF2371 PF10177.9 CUU98633.1 - 1 9.5 8.2 2.3 8.4 0.0 3.3 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF4131 PF13567.6 CUU98633.1 - 2.1 8.0 14.0 0.062 12.9 0.9 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Picorna_P3A PF06363.11 CUU98633.1 - 5 7.0 5.3 4.1 7.4 0.3 3.2 2 1 0 3 3 3 0 Picornaviridae P3A protein COX15-CtaA PF02628.15 CUU98633.1 - 8 5.4 11.0 22 4.0 5.6 2.5 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein Staufen_C PF16482.5 CUU98634.1 - 0.094 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Staufen C-terminal domain Toxin_5 PF05294.13 CUU98635.1 - 0.19 12.2 1.1 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 Scorpion short toxin DUF4645 PF15488.6 CUU98641.1 - 3.1 7.2 7.8 4 6.8 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) LRR_6 PF13516.6 CUU98645.1 - 3.4e-09 36.0 2.1 0.0012 18.7 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeat UPF0029 PF01205.19 CUU98647.1 - 1.7e-28 99.0 0.0 7.7e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CUU98647.1 - 1.1e-10 41.8 0.4 5.3e-10 39.6 0.4 2.0 1 1 0 1 1 1 1 RWD domain Aa_trans PF01490.18 CUU98648.1 - 3.3e-61 207.2 31.2 3.7e-47 161.0 23.0 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Sdh_cyt PF01127.22 CUU98649.1 - 1.6e-19 70.1 1.4 2.5e-19 69.5 1.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 CUU98650.1 - 2.3e-19 69.6 2.2 3.6e-19 69.0 2.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ets PF00178.22 CUU98651.1 - 6.2e-33 113.1 0.3 1.6e-32 111.8 0.3 1.8 1 0 0 1 1 1 1 Ets-domain CRM1_repeat_3 PF18787.1 CUU98651.1 - 0.048 13.8 0.3 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 zf-trcl PF13451.6 CUU98651.1 - 0.073 13.0 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain Aa_trans PF01490.18 CUU98652.1 - 4.4e-41 141.0 17.2 6e-28 97.7 6.8 2.2 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF4271 PF14093.6 CUU98652.1 - 2 8.3 14.3 0.051 13.5 6.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Elongin_A PF06881.11 CUU98653.1 - 1.1e-17 64.4 0.9 3.2e-17 62.9 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.11 CUU98653.1 - 1.7e-07 31.1 0.2 6.4e-07 29.3 0.2 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain UBN_AB PF14075.6 CUU98655.1 - 7.6e-29 101.0 0.1 1.3e-28 100.2 0.1 1.4 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 CUU98655.1 - 4.2e-14 52.3 0.0 1.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain NTP_transferase PF00483.23 CUU98657.1 - 1.4e-11 44.5 0.1 1.6e-08 34.4 0.1 3.0 1 1 1 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 CUU98657.1 - 4.3e-11 42.1 3.0 5.9e-08 32.1 0.7 3.0 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CUU98657.1 - 0.013 15.2 1.8 0.013 15.2 1.8 3.2 3 2 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CUU98657.1 - 0.033 12.3 0.0 0.042 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Sdh_cyt PF01127.22 CUU98658.1 - 1.6e-19 70.1 1.4 2.5e-19 69.5 1.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 CUU98659.1 - 2.3e-19 69.6 2.2 3.6e-19 69.0 2.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RIIa PF02197.17 CUU98660.1 - 2.3e-10 39.9 0.1 3.3e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit STT3_PglB_C PF18527.1 CUU98662.1 - 0.054 13.6 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 STT3/PglB C-terminal beta-barrel domain PhoLip_ATPase_C PF16212.5 CUU98664.1 - 7.1e-15 55.4 7.8 8.8e-15 55.1 7.8 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal HIG_1_N PF04588.13 CUU98665.1 - 3.8e-15 55.8 0.2 5.4e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TNFR_16_TM PF18422.1 CUU98665.1 - 0.071 13.1 0.2 0.95 9.5 0.0 2.4 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Tetraspanin PF00335.20 CUU98668.1 - 0.00086 19.1 0.6 0.0011 18.8 0.6 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3098 PF11297.8 CUU98668.1 - 0.0018 17.8 0.8 0.0033 17.0 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3098) Ammonium_transp PF00909.21 CUU98668.1 - 0.0092 14.7 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family COX2_TM PF02790.15 CUU98668.1 - 0.04 14.1 0.2 0.11 12.7 0.3 1.6 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2627 PF11118.8 CUU98668.1 - 0.046 14.3 1.1 0.065 13.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Neurensin PF14927.6 CUU98668.1 - 0.15 11.7 1.2 0.22 11.2 1.2 1.4 1 1 0 1 1 1 0 Neurensin GF_recep_IV PF14843.6 CUU98670.1 - 0.00033 20.5 26.4 0.0063 16.3 22.6 2.9 2 1 0 2 2 2 1 Growth factor receptor domain IV Furin-like PF00757.20 CUU98670.1 - 0.0014 18.5 23.9 0.64 9.9 21.3 2.6 2 1 0 2 2 2 2 Furin-like cysteine rich region Furin-like_2 PF15913.5 CUU98670.1 - 0.016 15.3 13.9 0.071 13.3 1.7 3.2 3 0 0 3 3 3 0 Furin-like repeat, cysteine-rich Peptidase_S8 PF00082.22 CUU98671.1 - 2.7e-12 46.6 1.3 3.4e-12 46.3 1.3 1.0 1 0 0 1 1 1 1 Subtilase family TRAM1 PF08390.11 CUU98672.1 - 2.3e-15 56.0 0.3 5.3e-15 54.8 0.3 1.6 1 0 0 1 1 1 1 TRAM1-like protein CstA PF02554.14 CUU98672.1 - 0.01 14.8 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF4044 PF13253.6 CUU98673.1 - 0.039 13.5 0.3 0.086 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) TRAM_LAG1_CLN8 PF03798.16 CUU98673.1 - 0.057 13.1 18.1 0.068 12.9 18.1 1.1 1 0 0 1 1 1 0 TLC domain TMEM208_SND2 PF05620.11 CUU98673.1 - 2.8 7.7 8.6 0.11 12.3 0.6 2.2 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 STT3 PF02516.14 CUU98674.1 - 1.5e-92 311.1 37.8 4.8e-46 157.7 19.2 3.1 2 1 1 3 3 3 3 Oligosaccharyl transferase STT3 subunit CrgA PF06781.12 CUU98674.1 - 0.041 13.9 0.1 0.78 9.8 0.0 2.7 2 0 0 2 2 2 0 Cell division protein CrgA 2OG-FeII_Oxy_2 PF13532.6 CUU98675.1 - 1.8e-07 31.5 0.0 2.8e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Got1 PF04178.12 CUU98676.1 - 1.3e-14 54.6 12.4 1.7e-14 54.2 12.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2151 PF10221.9 CUU98677.1 - 7.8e-62 209.9 0.0 1e-61 209.5 0.0 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator Sgf11_N PF18519.1 CUU98677.1 - 0.065 12.8 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain zf-AN1 PF01428.16 CUU98678.1 - 1.1e-19 70.3 21.6 3.9e-12 46.1 7.4 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CUU98678.1 - 0.0004 20.7 15.6 0.018 15.4 5.1 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain UIM PF02809.20 CUU98678.1 - 0.01 15.7 1.1 0.01 15.7 1.1 1.8 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF530 PF04409.12 CUU98678.1 - 0.18 10.1 4.2 0.49 8.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF530) IBR PF01485.21 CUU98678.1 - 1.6 9.0 18.7 3.9 7.8 1.2 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Innexin PF00876.18 CUU98679.1 - 7.5e-159 528.7 8.6 1e-96 324.3 4.6 2.0 2 0 0 2 2 2 2 Innexin DPM3 PF08285.11 CUU98679.1 - 1.9e-05 24.8 0.0 0.63 10.3 0.0 3.5 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4209 PF13910.6 CUU98679.1 - 0.04 14.2 0.3 19 5.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) Cdh1_DBD_1 PF18196.1 CUU98679.1 - 0.041 14.2 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Phospholamban PF04272.14 CUU98679.1 - 0.056 12.9 2.7 11 5.6 0.2 3.3 2 0 0 2 2 2 0 Phospholamban Insulin_TMD PF17870.1 CUU98679.1 - 0.22 11.6 2.4 26 5.0 0.2 3.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MGC-24 PF05283.11 CUU98679.1 - 1.2 9.6 6.8 20 5.6 0.0 3.1 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF378 PF04070.12 CUU98679.1 - 2.3 8.1 12.7 9.9 6.1 2.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF378) GlpM PF06942.12 CUU98679.1 - 7.2 7.1 9.5 18 5.8 0.3 3.4 3 0 0 3 3 3 0 GlpM protein RtcB PF01139.17 CUU98680.1 - 1.2e-76 258.5 1.4 4.1e-65 220.6 0.0 2.0 2 0 0 2 2 2 2 tRNA-splicing ligase RtcB WD40 PF00400.32 CUU98681.1 - 0.038 14.9 0.4 0.66 11.0 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat PK PF00224.21 CUU98683.1 - 1.2e-113 379.6 0.1 2e-113 378.8 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain C2 PF00168.30 CUU98683.1 - 2.8e-31 107.8 0.0 6.1e-09 36.1 0.0 3.4 3 0 0 3 3 3 3 C2 domain PK_C PF02887.16 CUU98683.1 - 2.2e-18 66.6 0.0 6.3e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain PRT_C PF08372.10 CUU98683.1 - 3.3e-09 36.7 0.0 7.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal HpcH_HpaI PF03328.14 CUU98683.1 - 0.004 16.3 0.6 0.007 15.5 0.1 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Pex24p PF06398.11 CUU98683.1 - 0.011 14.7 1.9 0.023 13.7 1.9 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF639 PF04842.12 CUU98683.1 - 0.058 12.8 1.2 0.4 10.1 0.1 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) UDPG_MGDP_dh_N PF03721.14 CUU98684.1 - 1.7e-60 203.8 0.1 2.2e-60 203.5 0.1 1.0 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CUU98684.1 - 0.0033 17.6 0.0 0.0069 16.6 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CUU98684.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CUU98684.1 - 0.089 13.1 0.1 0.42 10.9 0.0 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thioredoxin PF00085.20 CUU98685.1 - 1.1e-49 166.6 0.0 3.3e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CUU98685.1 - 1.6e-14 54.2 0.0 1.4e-06 28.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CUU98685.1 - 7.2e-08 32.9 0.8 0.012 16.1 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CUU98685.1 - 1.7e-07 30.9 0.0 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CUU98685.1 - 2e-06 28.0 0.4 0.089 13.1 0.2 4.2 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CUU98685.1 - 2.1e-05 24.3 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CUU98685.1 - 4e-05 23.7 0.1 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 CUU98685.1 - 9e-05 22.5 0.0 0.51 10.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.21 CUU98685.1 - 0.00016 21.5 0.1 0.32 10.9 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Fmp27_SW PF10305.9 CUU98685.1 - 0.012 16.3 0.0 0.044 14.5 0.0 2.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HyaE PF07449.11 CUU98685.1 - 0.013 15.5 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CUU98685.1 - 0.036 13.9 0.0 33 4.2 0.0 3.1 3 0 0 3 3 3 0 F plasmid transfer operon protein BNIP3 PF06553.12 CUU98685.1 - 0.11 12.2 1.9 0.46 10.1 0.8 2.2 3 0 0 3 3 3 0 BNIP3 zf-CCHC PF00098.23 CUU98686.1 - 2.4e-07 30.5 3.4 5.5e-07 29.4 3.4 1.7 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.29 CUU98686.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_3 PF13917.6 CUU98686.1 - 0.0061 16.5 0.4 0.0061 16.5 0.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 CUU98686.1 - 0.12 12.3 2.8 0.2 11.5 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CUU98686.1 - 3.6 7.4 10.6 0.14 11.9 2.7 2.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Helicase_C PF00271.31 CUU98687.1 - 4.3e-20 72.1 0.3 5.2e-18 65.4 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CUU98687.1 - 8.1e-05 22.5 0.0 0.00028 20.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.13 CUU98687.1 - 0.013 14.7 0.7 4.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ribosomal_S15 PF00312.22 CUU98687.1 - 0.11 12.8 0.1 30 4.9 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S15 DUF2026 PF09641.10 CUU98687.1 - 0.32 10.6 1.6 22 4.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) Choline_kinase PF01633.20 CUU98690.1 - 2.6e-47 161.2 0.0 2.8e-23 82.6 0.1 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase DUF4813 PF16072.5 CUU98690.1 - 0.00023 20.9 1.5 0.00038 20.2 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) APH PF01636.23 CUU98690.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 CUU98690.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic EcKinase PF02958.20 CUU98690.1 - 0.17 11.2 0.5 0.26 10.6 0.5 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase BTB_2 PF02214.22 CUU98691.1 - 1.9e-60 201.2 0.0 7e-29 100.0 0.0 2.0 2 0 0 2 2 2 2 BTB/POZ domain BTB_3 PF16017.5 CUU98691.1 - 5.1e-06 26.5 0.0 0.19 11.9 0.0 2.9 2 2 0 2 2 2 2 BTB/POZ domain Peptidase_M9 PF01752.17 CUU98691.1 - 5.2e-06 25.9 0.0 0.083 12.1 0.0 2.1 2 0 0 2 2 2 2 Collagenase DUF2982 PF11201.8 CUU98691.1 - 0.064 12.8 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2982) DASH_Duo1 PF08651.10 CUU98691.1 - 0.073 12.8 0.0 18 5.2 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Ribosomal_L7Ae PF01248.26 CUU98692.1 - 2e-06 27.5 1.5 1.5e-05 24.6 0.7 2.8 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family tRNA_bind PF01588.20 CUU98692.1 - 0.0052 16.9 1.4 0.15 12.2 0.3 2.6 2 0 0 2 2 2 1 Putative tRNA binding domain Spt5_N PF11942.8 CUU98692.1 - 0.29 12.2 9.5 0.6 11.1 1.4 3.6 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal DUF758 PF05527.11 CUU98693.1 - 3.9e-28 98.7 0.1 4.9e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF758) YwpF PF14183.6 CUU98693.1 - 0.022 14.7 0.1 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 YwpF-like protein Chromo_shadow PF01393.19 CUU98698.1 - 0.011 15.8 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 Chromo shadow domain Pilin_PilX PF11530.8 CUU98699.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Minor type IV pilin, PilX Ribosomal_L2 PF00181.23 CUU98699.1 - 0.14 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain NatB_MDM20 PF09797.9 CUU98700.1 - 1.4e-21 76.9 0.0 2.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Dehydratase_hem PF13816.6 CUU98702.1 - 0.21 10.9 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Sugar_tr PF00083.24 CUU98704.1 - 7.9e-22 77.7 22.3 2.8e-21 75.9 22.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CUU98704.1 - 3e-15 56.0 25.2 3.6e-15 55.7 23.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CUU98705.1 - 5.5e-17 61.8 2.5 7.4e-17 61.3 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CUU98705.1 - 2.4e-13 49.8 4.8 5.1e-13 48.7 4.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4220 PF13968.6 CUU98706.1 - 0.072 12.5 2.3 0.061 12.7 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) La PF05383.17 CUU98709.1 - 5.6e-06 26.3 0.1 9.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 La domain MFS_1 PF07690.16 CUU98711.1 - 1.6e-16 60.2 6.3 2.1e-16 59.8 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Transposase_1 PF01359.18 CUU98711.1 - 9.7e-09 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) Sugar_tr PF00083.24 CUU98711.1 - 3.8e-06 26.1 0.3 4.6e-06 25.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 CUU98711.1 - 0.002 16.7 1.4 0.0027 16.3 1.4 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Hemocyanin_C PF03723.14 CUU98711.1 - 0.21 10.9 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Hemocyanin, ig-like domain MFS_1 PF07690.16 CUU98712.1 - 1.7e-44 152.2 39.6 1.3e-34 119.7 31.4 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CUU98712.1 - 0.00015 20.8 2.8 0.00015 20.8 2.8 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CUU98712.1 - 0.02 13.7 21.4 0.25 10.1 7.7 2.3 1 1 1 2 2 2 0 MFS_1 like family MscL PF01741.18 CUU98712.1 - 0.56 10.5 2.4 5.5 7.3 0.1 2.9 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL MPS-4 PF17523.2 CUU98712.1 - 1.9 8.7 3.7 2.7 8.2 0.5 2.5 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Peptidase_M49 PF03571.15 CUU98717.1 - 5.4e-203 675.3 0.0 6.3e-203 675.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Peptidase_M49 PF03571.15 CUU98718.1 - 5.4e-203 675.3 0.0 6.3e-203 675.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF3695 PF12494.8 CUU98721.1 - 3.4e-15 55.7 0.1 4.9e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) MafB19-deam PF14437.6 CUU98721.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase DUF4762 PF15959.5 CUU98722.1 - 0.032 14.2 0.2 0.043 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Methyltransf_33 PF10017.9 CUU98723.1 - 0.0063 15.7 0.0 13 4.9 0.0 2.9 1 1 2 3 3 3 3 Histidine-specific methyltransferase, SAM-dependent Xol-1_N PF09108.10 CUU98723.1 - 0.024 14.5 0.3 16 5.3 0.0 2.9 1 1 2 3 3 3 0 Switch protein XOL-1, N-terminal SapB_1 PF05184.15 CUU98723.1 - 1.8 8.6 5.0 94 3.2 0.1 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 IF3_C PF00707.22 CUU98724.1 - 0.021 14.8 0.2 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Anillin PF08174.11 CUU98725.1 - 4.6e-14 53.0 0.0 4.4e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Cell division protein anillin HR1 PF02185.16 CUU98725.1 - 0.025 14.7 1.6 0.055 13.6 1.6 1.6 1 0 0 1 1 1 0 Hr1 repeat M3 PF09213.10 CUU98727.1 - 0.00049 18.9 0.1 0.32 9.6 0.0 2.1 1 1 1 2 2 2 2 M3 DUF1406 PF07190.11 CUU98727.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) AAA_16 PF13191.6 CUU98728.1 - 8e-05 23.1 0.0 8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CUU98728.1 - 0.00023 21.2 0.0 0.00024 21.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CUU98728.1 - 0.00052 19.5 0.0 0.00052 19.5 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CUU98728.1 - 0.00055 20.5 0.0 0.00057 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CUU98728.1 - 0.00063 19.6 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 CUU98728.1 - 0.0013 18.2 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CUU98728.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CUU98728.1 - 0.0043 17.3 0.0 0.0047 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CUU98728.1 - 0.013 14.7 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CUU98728.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 CUU98728.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 CUU98728.1 - 0.029 14.8 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CUU98728.1 - 0.041 13.8 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CUU98728.1 - 0.075 12.7 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CUU98728.1 - 0.13 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad1 PF02144.16 CUU98729.1 - 1.5e-29 102.9 0.0 1.7e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 zf-C2H2 PF00096.26 CUU98731.1 - 9.1e-16 57.4 25.0 3.9e-06 27.0 2.9 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CUU98731.1 - 1.3e-11 44.3 30.2 8.1e-06 26.0 3.9 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CUU98731.1 - 5.8e-10 39.1 17.4 0.0032 18.2 1.2 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CUU98731.1 - 0.00021 21.2 15.1 0.00038 20.4 0.5 4.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CUU98731.1 - 0.00036 20.7 8.2 0.22 11.8 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CUU98731.1 - 0.0015 18.8 7.2 0.029 14.6 1.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 CUU98731.1 - 0.024 15.0 0.3 0.024 15.0 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 CUU98731.1 - 6.2 6.8 6.9 2.5 8.1 0.7 2.5 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AMP_N PF05195.16 CUU98733.1 - 1.3e-22 79.8 0.0 1.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CUU98734.1 - 7.9e-32 110.6 0.1 8.5e-28 97.5 0.0 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.16 CUU98734.1 - 9.5e-28 96.4 0.0 1.6e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CybS PF05328.12 CUU98735.1 - 2e-20 72.9 0.3 2.3e-20 72.7 0.3 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF3995 PF13160.6 CUU98735.1 - 0.0087 16.4 1.4 0.011 16.1 0.2 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3995) Robl_LC7 PF03259.17 CUU98736.1 - 3.2e-13 49.2 0.0 4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain zf-C2HC_2 PF13913.6 CUU98737.1 - 1.5e-10 40.7 17.3 3.1e-06 26.9 1.7 3.7 4 0 0 4 4 3 2 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 CUU98737.1 - 0.00031 20.4 1.9 0.00031 20.4 1.9 3.2 4 0 0 4 4 4 1 zinc-ribbon domain DZR PF12773.7 CUU98737.1 - 0.00044 20.2 1.6 0.00044 20.2 1.6 3.1 3 1 0 3 3 3 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 CUU98737.1 - 0.0038 17.9 1.3 0.0038 17.9 1.3 3.9 3 0 0 3 3 3 1 zinc-ribbon family zf-ribbon_3 PF13248.6 CUU98737.1 - 0.0088 15.4 1.3 0.0088 15.4 1.3 2.2 3 0 0 3 3 2 1 zinc-ribbon domain Nudix_N_2 PF14803.6 CUU98737.1 - 0.013 15.4 2.6 3.3 7.7 0.2 3.0 2 0 0 2 2 2 0 Nudix N-terminal Sgf11 PF08209.11 CUU98737.1 - 0.032 13.8 7.6 1.5 8.5 1.1 2.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) FYVE PF01363.21 CUU98737.1 - 0.069 13.3 13.7 1.4 9.1 0.6 3.7 3 0 0 3 3 3 0 FYVE zinc finger MapZ_EC1 PF18041.1 CUU98737.1 - 0.11 12.7 4.9 0.12 12.6 0.6 2.7 1 1 1 2 2 2 0 MapZ extracellular domain 1 zf-CHCC PF10276.9 CUU98737.1 - 0.23 11.5 10.1 1.3 9.2 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2 PF00096.26 CUU98737.1 - 0.93 10.1 12.2 9.3 6.9 0.8 4.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type UPF0547 PF10571.9 CUU98737.1 - 1.1 9.4 4.3 0.33 11.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.11 CUU98737.1 - 6.8 6.4 9.3 1.6 8.4 0.2 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain HSP90 PF00183.18 CUU98738.1 - 6.1e-167 556.6 25.1 9.7e-86 288.7 11.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CUU98738.1 - 7e-13 48.6 0.1 1.8e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CUU98738.1 - 2.6e-09 37.6 0.3 5.6e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HCMV_UL124 PF17609.2 CUU98739.1 - 0.071 13.3 0.8 0.18 12.0 0.4 1.8 1 1 0 1 1 1 0 Family of unknown function COX17 PF05051.13 CUU98740.1 - 2.6e-17 62.9 5.6 2.6e-17 62.9 5.6 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Ala_racemase_N PF01168.20 CUU98740.1 - 2.1e-16 60.3 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Rep_fac-A_3 PF08661.11 CUU98740.1 - 2e-08 34.5 0.0 5.2e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Replication factor A protein 3 Sec3_C PF09763.9 CUU98741.1 - 1.1e-64 219.1 20.1 1.9e-44 152.2 0.8 3.4 2 1 1 3 3 3 3 Exocyst complex component Sec3 STAG PF08514.11 CUU98741.1 - 0.043 13.7 3.4 10 6.1 0.5 4.4 3 1 0 3 3 3 0 STAG domain Per1 PF04080.13 CUU98742.1 - 2.8e-69 233.7 17.5 3.6e-69 233.4 17.5 1.1 1 0 0 1 1 1 1 Per1-like family Polyketide_cyc PF03364.20 CUU98742.1 - 2.9e-23 82.5 0.0 5.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SPC12 PF06645.13 CUU98742.1 - 0.047 13.8 5.4 0.034 14.2 2.3 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ING PF12998.7 CUU98743.1 - 1.8e-25 89.4 23.0 4.3e-13 49.7 4.3 3.1 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 CUU98743.1 - 2.3e-11 43.6 0.1 2.3e-11 43.6 0.1 3.8 3 2 0 3 3 3 1 Swi5 PHD PF00628.29 CUU98743.1 - 1.4e-07 31.3 8.5 0.0012 18.7 0.6 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 CUU98743.1 - 6.7e-07 29.5 0.3 0.079 13.2 0.0 3.0 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CUU98743.1 - 1.8e-05 24.9 0.5 0.19 11.9 0.0 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain DUF1002 PF06207.11 CUU98743.1 - 0.00072 19.2 20.5 0.079 12.5 6.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1002) RasGEF PF00617.19 CUU98743.1 - 0.0012 19.1 2.6 1.6 8.9 0.1 2.9 3 0 0 3 3 3 2 RasGEF domain Inhibitor_I48 PF10467.9 CUU98743.1 - 0.0044 16.9 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase inhibitor clitocypin PKHD_C PF18331.1 CUU98743.1 - 0.0078 16.3 4.2 35 4.6 0.1 4.6 4 0 0 4 4 4 0 PKHD-type hydroxylase C-terminal domain Phage_Capsid_P3 PF09018.11 CUU98743.1 - 0.011 14.6 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 P3 major capsid protein Flagellar_rod PF05149.12 CUU98743.1 - 0.015 14.7 14.3 0.12 11.9 1.7 2.8 3 0 0 3 3 3 0 Paraflagellar rod protein Cbl_N PF02262.16 CUU98743.1 - 0.043 13.8 4.6 2.5 8.1 0.2 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 SAT PF16073.5 CUU98743.1 - 0.09 12.5 0.5 0.34 10.6 0.5 2.0 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Exotox-A_target PF09102.10 CUU98743.1 - 0.096 12.7 0.4 26 4.8 0.0 3.0 3 0 0 3 3 3 0 Exotoxin A, targeting zf-PARP PF00645.18 CUU98743.1 - 0.11 13.4 2.9 12 6.8 0.0 3.6 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Intein_splicing PF14890.6 CUU98743.1 - 0.26 11.2 1.4 33 4.4 0.1 2.9 2 0 0 2 2 2 0 Intein splicing domain DUF948 PF06103.11 CUU98743.1 - 0.32 11.3 9.1 9.8 6.5 0.6 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-C4pol PF14260.6 CUU98743.1 - 0.77 10.3 10.4 7.9 7.0 0.8 3.7 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta CFEM PF05730.11 CUU98743.1 - 0.81 9.8 6.6 10 6.3 0.5 2.5 2 0 0 2 2 2 0 CFEM domain TruB_C_2 PF16198.5 CUU98743.1 - 0.97 9.6 3.2 39 4.5 0.1 2.9 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain VWC PF00093.18 CUU98743.1 - 2 8.8 5.4 24 5.4 0.5 2.4 2 0 0 2 2 2 0 von Willebrand factor type C domain zf-C4H2 PF10146.9 CUU98743.1 - 3.3 7.9 16.6 2.6 8.3 1.9 2.9 2 1 0 3 3 3 0 Zinc finger-containing protein SbcD_C PF12320.8 CUU98743.1 - 9.2 6.6 9.8 20 5.6 0.9 3.0 3 0 0 3 3 2 0 Type 5 capsule protein repressor C-terminal domain DSPc PF00782.20 CUU98744.1 - 4e-33 114.0 0.0 7.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 CUU98744.1 - 5.5e-08 32.6 0.5 1.2e-07 31.5 0.5 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 CUU98744.1 - 0.0048 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Tub_N PF16322.5 CUU98744.1 - 3.3 8.0 7.2 0.19 12.1 1.2 2.1 3 0 0 3 3 3 0 Tubby N-terminal Neur_chan_LBD PF02931.23 CUU98745.1 - 1.2e-12 47.7 1.0 2.1e-12 47.0 1.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF1951 PF09188.10 CUU98745.1 - 0.15 12.1 0.7 0.5 10.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) Neur_chan_memb PF02932.16 CUU98745.1 - 2.1 8.4 12.6 0.061 13.4 4.9 2.2 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF2054 PF10218.9 CUU98746.1 - 6.1e-34 117.0 14.5 9.2e-34 116.4 14.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Zip PF02535.22 CUU98747.1 - 9.7e-15 54.6 3.6 1.2e-14 54.3 2.8 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter DUF3792 PF12670.7 CUU98747.1 - 0.73 10.0 7.1 7.4 6.8 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Zip PF02535.22 CUU98748.1 - 4.3e-53 180.7 8.5 5.6e-53 180.3 8.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter FRG2 PF15315.6 CUU98748.1 - 0.19 11.9 4.3 0.35 11.1 4.3 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Vac7 PF12751.7 CUU98748.1 - 1.5 8.2 9.6 2.3 7.5 9.6 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 RVP PF00077.20 CUU98749.1 - 0.00014 22.1 0.0 0.21 11.9 0.0 3.5 2 2 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CUU98749.1 - 0.0011 19.5 0.0 1.6 9.4 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CUU98749.1 - 0.0015 19.0 0.0 0.34 11.5 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease AIMP2_LysRS_bd PF16780.5 CUU98750.1 - 0.046 13.4 0.3 0.077 12.7 0.2 1.5 1 1 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain PAP_assoc PF03828.19 CUU98751.1 - 1.6e-11 44.3 6.0 2.2e-05 24.5 0.1 3.4 3 1 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CUU98751.1 - 1.9e-10 40.9 0.0 3.6e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 CUU98751.1 - 1.1e-06 28.6 0.0 3.8e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase LysM PF01476.20 CUU98752.1 - 0.00094 19.2 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 LysM domain Phtf-FEM1B_bdg PF12129.8 CUU98754.1 - 1.7e-44 151.3 0.3 5.8e-26 91.2 0.2 2.2 2 0 0 2 2 2 2 Male germ-cell putative homeodomain transcription factor 5TM-5TMR_LYT PF07694.12 CUU98754.1 - 0.00013 21.5 2.7 0.26 10.8 0.2 2.2 2 0 0 2 2 2 2 5TMR of 5TMR-LYT SFTA2 PF15210.6 CUU98754.1 - 0.062 13.2 1.7 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Surfactant-associated protein 2 UK PF02512.14 CUU98754.1 - 0.072 13.6 0.4 23 5.6 0.1 2.5 2 0 0 2 2 2 0 Virulence determinant FixS PF03597.15 CUU98754.1 - 0.26 11.0 0.9 26 4.6 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF3012 PF11216.8 CUU98754.1 - 0.47 10.5 5.4 11 6.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Collagen PF01391.18 CUU98759.1 - 4.3e-157 510.0 691.9 5.5e-09 35.6 38.6 20.5 1 1 12 13 13 13 10 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CUU98759.1 - 3.5e-37 127.9 0.0 1.1e-36 126.3 0.0 1.7 1 1 0 1 1 1 1 Fibrillar collagen C-terminal domain fn3 PF00041.21 CUU98760.1 - 2e-42 143.4 0.7 4e-10 39.9 0.0 6.4 5 1 0 5 5 5 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CUU98760.1 - 1.2e-10 41.8 2.7 0.25 12.0 0.0 5.8 6 1 0 6 6 6 4 Purple acid Phosphatase, N-terminal domain Neogenin_C PF06583.12 CUU98760.1 - 1.1e-07 31.9 15.7 1.8e-06 28.0 15.7 2.6 1 1 0 1 1 1 1 Neogenin C-terminus EphA2_TM PF14575.6 CUU98760.1 - 0.041 14.8 0.1 0.094 13.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CUU98760.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family DUF2369 PF10179.9 CUU98760.1 - 0.12 12.7 0.0 37 4.8 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) NYD-SP28_assoc PF14775.6 CUU98761.1 - 0.0052 16.8 1.7 0.0097 16.0 1.7 1.5 1 0 0 1 1 1 1 Sperm tail C-terminal domain DUF3426 PF11906.8 CUU98761.1 - 0.16 12.1 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) DUF2070 PF09843.9 CUU98762.1 - 6.3 5.0 7.7 7.6 4.7 7.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMEM43 PF07787.12 CUU98762.1 - 7.8 5.8 5.6 11 5.3 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 LRR19-TM PF15176.6 CUU98763.1 - 0.42 10.6 4.2 0.13 12.2 0.8 1.9 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2070 PF09843.9 CUU98763.1 - 0.54 8.5 2.9 0.65 8.2 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GRIM-19 PF06212.12 CUU98764.1 - 2.3e-44 150.6 0.2 2.7e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 GRIM-19 protein LSM PF01423.22 CUU98765.1 - 1.9e-16 59.5 0.1 2.2e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CUU98765.1 - 0.093 12.9 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 CUU98765.1 - 0.15 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Hfq protein MH2 PF03166.14 CUU98769.1 - 9.2e-22 78.2 0.0 4.4e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 MH2 domain DUF2968 PF11180.8 CUU98770.1 - 0.013 15.1 6.9 0.036 13.7 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IL2 PF00715.17 CUU98770.1 - 0.047 13.6 0.3 0.047 13.6 0.3 2.8 3 1 0 3 3 3 0 Interleukin 2 Mad3_BUB1_I_2 PF17014.5 CUU98770.1 - 0.12 12.5 4.7 0.21 11.7 1.2 2.6 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Baculo_PEP_C PF04513.12 CUU98770.1 - 0.14 12.2 8.2 0.039 14.0 1.7 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NYD-SP28_assoc PF14775.6 CUU98770.1 - 0.27 11.4 8.0 0.045 13.8 1.9 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain COMP PF11598.8 CUU98770.1 - 0.36 11.3 3.4 6.4 7.3 0.8 2.8 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein PKK PF12474.8 CUU98770.1 - 2.5 8.2 20.2 2.3 8.3 10.6 2.8 2 1 0 2 2 2 0 Polo kinase kinase EF-hand_10 PF14788.6 CUU98771.1 - 0.077 12.9 0.6 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 EF hand DUF1690 PF07956.11 CUU98772.1 - 6.8 7.1 7.9 1.4 9.3 2.2 2.7 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Exo5 PF09810.9 CUU98774.1 - 0.018 14.6 0.2 0.021 14.3 0.2 1.0 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DEK_C PF08766.11 CUU98774.1 - 0.035 14.0 0.1 0.08 12.9 0.1 1.7 1 1 0 1 1 1 0 DEK C terminal domain Orf78 PF06024.12 CUU98774.1 - 0.075 13.3 0.2 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Orf78 (ac78) UPF0506 PF11703.8 CUU98776.1 - 1.4e-09 38.1 1.5 1.9e-09 37.8 1.5 1.2 1 0 0 1 1 1 1 UPF0506 DUF667 PF05018.13 CUU98777.1 - 0.019 14.7 0.3 0.023 14.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF667) TPR_8 PF13181.6 CUU98778.1 - 1.1e-06 28.3 10.6 3.8 8.0 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CUU98778.1 - 3.3e-06 27.1 0.5 4.5 7.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat PsbQ PF05757.11 CUU98778.1 - 4.3e-05 23.3 10.8 0.72 9.6 0.4 3.3 3 0 0 3 3 3 3 Oxygen evolving enhancer protein 3 (PsbQ) PB1 PF00564.24 CUU98778.1 - 0.0095 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain TMEM174 PF15029.6 CUU98778.1 - 0.01 15.6 0.0 44 3.7 0.0 3.6 3 0 0 3 3 3 0 Transmembrane protein 174 TPR_1 PF00515.28 CUU98778.1 - 0.018 14.9 26.3 6.9 6.7 0.4 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat GXWXG PF14231.6 CUU98778.1 - 0.024 14.7 0.1 78 3.5 0.0 3.3 3 0 0 3 3 3 0 GXWXG protein TPR_7 PF13176.6 CUU98778.1 - 0.052 13.6 17.9 46 4.4 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF5133 PF17196.4 CUU98778.1 - 0.062 13.5 8.9 23 5.3 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF5133) DUF3246 PF11596.8 CUU98778.1 - 0.13 11.6 10.9 2.8 7.3 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) Defensin_big PF14862.6 CUU98778.1 - 0.41 11.0 4.2 1.2e+02 3.1 0.1 4.0 3 0 0 3 3 3 0 Big defensin Med6 PF04934.14 CUU98778.1 - 0.91 9.3 10.3 24 4.7 0.3 3.5 3 0 0 3 3 3 0 MED6 mediator sub complex component FNIP PF05725.12 CUU98778.1 - 1.1 9.5 2.5 2e+02 2.3 0.1 3.6 3 0 0 3 3 3 0 FNIP Repeat TPR_2 PF07719.17 CUU98778.1 - 1.4 9.3 23.5 3.5 8.0 0.6 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 CUU98778.1 - 3.1 8.3 29.1 17 5.8 3.3 4.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain DAGK_cat PF00781.24 CUU98780.1 - 7.5e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Torsin PF06309.11 CUU98781.1 - 1.1e-32 112.8 1.5 2.2e-32 111.9 1.5 1.5 1 0 0 1 1 1 1 Torsin NB-ARC PF00931.22 CUU98781.1 - 0.2 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Lig_chan PF00060.26 CUU98782.1 - 9.8e-15 54.7 0.5 2.1e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CUU98782.1 - 6.2e-12 45.4 0.0 3e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 CUU98782.1 - 9.3e-09 35.5 0.0 2.9e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF4625 PF15418.6 CUU98782.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Lig_chan PF00060.26 CUU98783.1 - 4.3e-13 49.4 0.4 9.7e-13 48.2 0.4 1.8 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 CUU98783.1 - 1.6e-09 37.6 0.0 1.5e-08 34.3 0.0 2.6 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 CUU98783.1 - 0.00025 21.2 0.0 0.00062 19.9 0.0 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site GTP_cyclohydroI PF01227.22 CUU98784.1 - 2e-72 242.4 0.9 2.7e-72 242.0 0.9 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CUU98784.1 - 0.00094 19.3 0.0 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein DUF1830 PF08865.11 CUU98785.1 - 0.0061 16.5 0.3 0.015 15.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1830) Cnd1 PF12717.7 CUU98785.1 - 0.066 13.2 5.7 0.092 12.8 1.3 3.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 CUU98785.1 - 1.4 9.0 10.5 4.6 7.4 0.1 4.7 4 1 1 5 5 5 0 Telomere-length maintenance and DNA damage repair TPR_14 PF13428.6 CUU98786.1 - 7.1e-06 26.4 0.0 0.0027 18.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU98786.1 - 7.4e-06 26.4 0.0 0.00022 21.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CUU98786.1 - 1.4e-05 25.2 0.0 0.00031 20.9 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CUU98786.1 - 0.003 17.3 0.0 0.11 12.4 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 CUU98786.1 - 0.0037 16.3 0.2 0.31 10.0 0.1 2.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 CUU98786.1 - 0.0049 17.0 0.3 0.54 10.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CUU98786.1 - 0.0062 16.8 0.1 1.7 9.2 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CUU98786.1 - 0.0073 16.3 0.0 0.08 13.1 0.0 3.0 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF4795 PF16043.5 CUU98786.1 - 0.093 12.3 0.7 0.28 10.8 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TPR_7 PF13176.6 CUU98786.1 - 0.1 12.7 0.0 63 4.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PDZ PF00595.24 CUU98787.1 - 1.3e-42 144.1 0.0 6.5e-15 55.2 0.0 3.1 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 CUU98787.1 - 2.2e-27 94.7 2.3 1.2e-07 31.5 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 CUU98787.1 - 6.5e-12 45.6 0.0 0.02 15.2 0.0 3.3 3 0 0 3 3 3 3 PDZ domain Phosphodiest PF01663.22 CUU98790.1 - 3.9e-10 39.9 0.0 5.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TMEM154 PF15102.6 CUU98790.1 - 0.0057 16.6 1.7 0.0057 16.6 1.7 1.6 2 0 0 2 2 2 1 TMEM154 protein family MGC-24 PF05283.11 CUU98790.1 - 0.021 15.2 4.4 0.021 15.2 4.4 1.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 CUU98790.1 - 0.18 12.0 7.5 0.34 11.1 7.5 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF599 PF04654.12 CUU98790.1 - 0.66 9.4 3.2 1.1 8.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SSP160 PF06933.11 CUU98790.1 - 1.1 7.3 10.8 1.5 6.9 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PACT_coil_coil PF10495.9 CUU98792.1 - 2.6e-18 66.4 0.6 1.7e-17 63.8 0.0 2.9 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein RNase_H2-Ydr279 PF09468.10 CUU98792.1 - 0.014 15.5 4.4 0.016 15.4 1.1 3.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ABATE PF07336.11 CUU98792.1 - 0.091 13.4 0.0 1.8 9.2 0.1 3.1 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Cadherin PF00028.17 CUU98793.1 - 4.3e-22 78.4 0.0 2.2e-09 37.6 0.0 3.6 2 1 0 2 2 2 2 Cadherin domain Cadherin_pro PF08758.11 CUU98793.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Cadherin prodomain like Tmemb_9 PF05434.11 CUU98793.1 - 0.62 10.0 0.0 0.62 10.0 0.0 2.6 2 1 1 3 3 3 0 TMEM9 MRP-L28 PF09812.9 CUU98799.1 - 1.3e-31 109.9 7.4 1.7e-31 109.5 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PurA PF04845.13 CUU98800.1 - 8.2e-42 143.0 0.2 1.3e-38 132.6 0.0 2.1 2 0 0 2 2 2 2 PurA ssDNA and RNA-binding protein DUF3276 PF11680.8 CUU98800.1 - 0.00078 19.6 1.1 0.66 10.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3276) RRP36 PF06102.12 CUU98801.1 - 6e-18 65.4 27.4 7.6e-18 65.0 27.4 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 GhoS PF11080.8 CUU98801.1 - 0.057 13.4 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 Endoribonuclease GhoS Mu-like_Pro PF10123.9 CUU98801.1 - 0.067 12.7 3.2 0.073 12.6 3.2 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein YkyA PF10368.9 CUU98802.1 - 0.0027 17.4 8.4 0.087 12.5 1.1 3.1 3 0 0 3 3 3 2 Putative cell-wall binding lipoprotein BLOC1_2 PF10046.9 CUU98802.1 - 0.058 13.7 3.3 0.14 12.5 0.7 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Translat_reg PF01818.17 CUU98802.1 - 0.068 13.1 0.4 0.2 11.6 0.1 1.9 2 1 0 2 2 2 0 Bacteriophage translational regulator TipAS PF07739.13 CUU98802.1 - 0.096 13.2 1.6 0.19 12.3 0.3 2.1 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain YolD PF08863.10 CUU98802.1 - 0.85 9.7 7.8 2.6 8.1 0.3 2.9 3 0 0 3 3 3 0 YolD-like protein Tetraspanin PF00335.20 CUU98803.1 - 2e-08 34.3 4.1 2.8e-08 33.8 4.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Myf5 PF12232.8 CUU98803.1 - 0.035 14.9 2.8 0.065 14.0 2.8 1.6 1 0 0 1 1 1 0 Myogenic determination factor 5 ALG11_N PF15924.5 CUU98804.1 - 2.5e-147 488.3 0.2 2.5e-72 243.3 0.0 2.2 2 0 0 2 2 2 2 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CUU98804.1 - 1.5e-30 106.0 0.0 1.3e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CUU98804.1 - 9e-16 58.5 0.0 5.9e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF2905 PF11146.8 CUU98804.1 - 0.00013 22.1 12.2 0.021 15.0 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2905) Glyco_transf_4 PF13439.6 CUU98804.1 - 0.00018 21.6 0.2 0.79 9.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 DUF2280 PF10045.9 CUU98804.1 - 0.00052 20.3 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2280) Beach PF02138.18 CUU98804.1 - 0.0041 16.5 0.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain GlutR_dimer PF00745.20 CUU98804.1 - 0.0066 16.9 0.0 4.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, dimerisation domain SAP PF02037.27 CUU98804.1 - 0.027 14.2 0.4 11 5.9 0.1 2.7 2 0 0 2 2 2 0 SAP domain Crystallin PF00525.18 CUU98804.1 - 0.16 12.2 0.7 41 4.4 0.1 3.2 2 0 0 2 2 2 0 Alpha crystallin A chain, N terminal Pkinase PF00069.25 CUU98807.1 - 3.3e-44 151.2 0.1 4.3e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98807.1 - 1.5e-19 70.3 0.0 2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.21 CUU98808.1 - 1.6e-18 66.8 0.0 4.3e-07 30.2 0.0 4.6 4 0 0 4 4 4 3 Fibronectin type III domain Y_phosphatase PF00102.27 CUU98808.1 - 9.7e-16 58.0 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pur_ac_phosph_N PF16656.5 CUU98808.1 - 0.013 16.0 0.6 25 5.5 0.0 3.7 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain SHP PF03579.13 CUU98808.1 - 0.053 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Small hydrophobic protein FH2 PF02181.23 CUU98809.1 - 5.9e-75 252.7 3.0 5.9e-75 252.7 3.0 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CUU98809.1 - 6.3e-23 81.4 6.2 1.8e-22 79.9 6.2 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CUU98809.1 - 2.8e-18 66.1 18.0 7.2e-11 42.0 1.5 3.3 3 0 0 3 3 2 2 Diaphanous GTPase-binding Domain Cob_adeno_trans PF01923.18 CUU98809.1 - 0.0043 17.2 4.9 1.9 8.6 3.9 2.9 2 0 0 2 2 2 1 Cobalamin adenosyltransferase ADIP PF11559.8 CUU98809.1 - 0.0055 16.8 13.8 0.022 14.9 13.8 2.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding AvrM-A PF18241.1 CUU98809.1 - 0.0056 17.1 2.1 0.0056 17.1 2.1 2.3 2 0 0 2 2 1 1 Flax-rust effector AvrM-A SseC PF04888.12 CUU98809.1 - 0.0068 16.0 4.9 0.028 14.0 5.1 1.9 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family DUF3584 PF12128.8 CUU98809.1 - 0.0081 13.7 14.3 0.016 12.7 14.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 CUU98809.1 - 0.033 14.7 17.0 1.3 9.5 0.1 5.0 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 CUU98809.1 - 0.076 11.7 7.2 0.16 10.6 7.2 1.5 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CUU98809.1 - 0.077 11.9 14.5 0.29 9.9 14.5 2.0 1 0 0 1 1 1 0 Spc7 kinetochore protein ING PF12998.7 CUU98809.1 - 0.1 13.2 3.5 8.9 7.0 0.0 3.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ZapD PF07072.11 CUU98809.1 - 0.14 11.9 8.6 0.42 10.3 8.6 1.9 1 0 0 1 1 1 0 Cell division protein DUF4795 PF16043.5 CUU98809.1 - 0.15 11.6 8.1 1.5 8.3 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) CENP-H PF05837.12 CUU98809.1 - 0.16 12.3 16.8 5.6 7.4 16.8 3.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 CUU98809.1 - 0.2 11.8 9.1 1.1 9.5 7.4 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 CUU98809.1 - 1.5 8.8 14.9 0.76 9.8 10.5 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Baculo_PEP_C PF04513.12 CUU98809.1 - 1.7 8.7 19.4 2.3 8.2 10.3 4.5 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 CUU98809.1 - 1.8 8.9 28.7 5.8 7.3 18.6 4.3 3 2 1 4 4 4 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 CUU98809.1 - 1.9 7.8 19.6 0.21 11.0 13.4 2.5 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CUU98809.1 - 2.3 8.3 8.9 6 6.9 6.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 CUU98809.1 - 2.3 8.5 11.5 16 5.8 3.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 CUU98809.1 - 6.6 6.9 18.4 7.7 6.7 11.5 3.1 1 1 1 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 CUU98809.1 - 6.8 5.8 8.5 5.6 6.1 6.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein Totivirus_coat PF05518.11 CUU98809.1 - 7.5 4.5 7.5 12 3.8 7.5 1.2 1 0 0 1 1 1 0 Totivirus coat protein FUSC PF04632.12 CUU98809.1 - 8.4 4.8 5.5 23 3.4 5.5 1.7 1 0 0 1 1 1 0 Fusaric acid resistance protein family GrpE PF01025.19 CUU98809.1 - 9.4 5.9 11.0 48 3.6 11.0 2.3 1 1 0 1 1 1 0 GrpE PolyA_pol PF01743.20 CUU98810.1 - 8.9e-31 106.9 0.9 1.6e-30 106.1 0.9 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CUU98810.1 - 3.1e-10 39.7 0.5 7.8e-09 35.2 0.0 3.1 4 0 0 4 4 4 1 Probable RNA and SrmB- binding site of polymerase A Myb_DNA-bind_2 PF08914.11 CUU98810.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Rap1 Myb domain SNAP-25 PF00835.19 CUU98811.1 - 0.14 12.4 0.2 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 SNAP-25 family HSP70 PF00012.20 CUU98812.1 - 8.3e-261 866.4 10.1 9.5e-261 866.2 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CUU98812.1 - 1.9e-18 66.4 2.7 8e-18 64.3 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 CUU98812.1 - 0.0025 18.2 2.1 5 7.6 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Cnd1_N PF12922.7 CUU98812.1 - 0.033 14.0 2.5 0.061 13.2 2.5 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term BcrAD_BadFG PF01869.20 CUU98812.1 - 0.04 13.4 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CUU98812.1 - 0.046 13.0 0.7 0.11 11.8 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CUU98812.1 - 0.076 12.7 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 CUU98812.1 - 2.1 7.6 13.2 0.36 10.1 9.5 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 RD3 PF14473.6 CUU98812.1 - 5 7.0 9.9 3.9 7.3 1.6 2.7 1 1 1 2 2 2 0 RD3 protein HSP70 PF00012.20 CUU98813.1 - 7.7e-119 397.6 3.4 8.7e-119 397.4 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 CUU98813.1 - 0.045 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3942 PF13078.6 CUU98816.1 - 0.038 14.3 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) PCNA_N PF00705.18 CUU98816.1 - 0.091 12.5 0.1 0.098 12.4 0.1 1.1 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Leo1 PF04004.13 CUU98817.1 - 4.5e-50 169.7 0.1 4.5e-50 169.7 0.1 1.8 2 0 0 2 2 2 1 Leo1-like protein SPT2 PF08243.11 CUU98818.1 - 3.1e-14 53.4 16.4 3.1e-14 53.4 16.4 2.0 2 0 0 2 2 2 1 SPT2 chromatin protein HUN PF08729.10 CUU98818.1 - 0.0061 16.5 8.2 0.014 15.4 8.2 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain LIM PF00412.22 CUU98821.1 - 5.9e-19 68.0 22.8 1.1e-09 38.4 2.4 2.3 2 0 0 2 2 2 2 LIM domain E6 PF00518.17 CUU98821.1 - 0.25 11.8 12.5 0.88 10.0 1.2 3.1 1 1 2 3 3 3 0 Early Protein (E6) NCD3G PF07562.14 CUU98821.1 - 5.1 7.1 19.1 0.73 9.9 7.7 2.8 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR VHP PF02209.19 CUU98822.1 - 1.1e-13 51.0 2.9 1.9e-13 50.2 2.9 1.4 1 0 0 1 1 1 1 Villin headpiece domain YjeF_N PF03853.15 CUU98824.1 - 0.0051 16.7 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CUU98824.1 - 0.0071 17.2 1.3 0.0071 17.2 1.3 2.0 2 0 0 2 2 2 1 FDF domain rRNA_processing PF08524.11 CUU98825.1 - 3.8e-06 27.0 19.7 5.3e-06 26.5 19.7 1.1 1 0 0 1 1 1 1 rRNA processing PA26 PF04636.13 CUU98825.1 - 0.00058 18.9 3.2 0.00061 18.8 3.2 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CDC37_N PF03234.14 CUU98825.1 - 0.032 15.1 4.4 0.032 15.1 4.4 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding RF-1 PF00472.20 CUU98825.1 - 0.07 13.1 11.0 0.1 12.6 11.0 1.3 1 0 0 1 1 1 0 RF-1 domain Ta0938 PF11494.8 CUU98825.1 - 0.92 9.8 4.1 0.77 10.1 2.2 1.7 1 1 1 2 2 2 0 Ta0938 PAF-AH_p_II PF03403.13 CUU98825.1 - 1.3 7.5 5.9 1.6 7.2 5.9 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1751 PF08551.10 CUU98827.1 - 5.3e-06 26.9 4.2 1.1e-05 25.9 4.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Ribosomal_S2 PF00318.20 CUU98828.1 - 4.2e-20 71.9 0.1 1.3e-12 47.4 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 DUF2367 PF10164.9 CUU98828.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) RNase_PH PF01138.21 CUU98829.1 - 4.7e-12 46.5 0.1 1.8e-11 44.7 0.0 1.9 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 TcfC PF16967.5 CUU98829.1 - 0.1 12.1 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 E-set like domain Complex1_49kDa PF00346.19 CUU98830.1 - 2.7e-18 66.1 0.0 8.9e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CUU98830.1 - 0.0047 15.9 0.0 0.033 13.1 0.0 1.9 2 0 0 2 2 2 1 Nickel-dependent hydrogenase Mito_carr PF00153.27 CUU98831.1 - 1e-44 150.4 5.9 1.4e-20 73.0 0.5 4.1 2 1 1 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 CUU98831.1 - 0.36 11.4 0.3 0.36 11.4 0.3 2.7 3 0 0 3 3 3 0 YtxH-like protein DUF3147 PF11345.8 CUU98831.1 - 0.68 10.3 4.4 1 9.7 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3147) RhoGAP PF00620.27 CUU98833.1 - 6.5e-37 126.7 0.1 1.1e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain Kp4 PF09044.10 CUU98833.1 - 0.02 14.9 0.4 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Kp4 EF-hand_1 PF00036.32 CUU98835.1 - 5.8e-18 63.0 2.6 1.2e-05 24.4 1.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CUU98835.1 - 2.2e-17 63.2 4.4 8.9e-12 45.3 3.2 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CUU98835.1 - 2.3e-13 49.7 3.4 0.00013 21.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU98835.1 - 5.8e-12 44.5 9.8 0.00013 21.3 0.7 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CUU98835.1 - 3.9e-11 41.9 5.8 0.0024 17.7 0.5 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_10 PF14788.6 CUU98835.1 - 1e-06 28.5 3.9 6.2e-06 26.0 1.0 2.4 1 1 1 2 2 2 2 EF hand EF-hand_4 PF12763.7 CUU98835.1 - 0.00024 21.0 5.9 0.17 11.9 0.1 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CUU98835.1 - 0.015 15.6 0.4 0.097 13.0 0.4 2.0 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CUU98835.1 - 0.12 12.6 2.9 3.9 7.8 0.8 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 CUU98836.1 - 3.7e-24 85.0 16.7 3.8e-10 40.1 1.6 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CUU98836.1 - 5e-24 82.0 11.0 3.8e-06 26.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CUU98836.1 - 1e-22 78.0 6.8 6.1e-06 25.7 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CUU98836.1 - 5.8e-19 66.7 12.9 3.5e-05 23.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CUU98836.1 - 2.9e-15 55.9 8.9 0.00013 21.7 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CUU98836.1 - 1.6e-09 38.1 1.1 0.00027 21.2 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CUU98836.1 - 0.0014 18.9 0.0 0.0072 16.6 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CUU98836.1 - 0.01 16.0 0.9 11 6.2 0.0 3.4 3 1 1 4 4 4 1 Dockerin type I domain Excalibur PF05901.11 CUU98836.1 - 0.054 14.1 2.7 2.5 8.8 0.1 3.4 4 0 0 4 4 4 0 Excalibur calcium-binding domain EF-hand_10 PF14788.6 CUU98836.1 - 0.054 13.4 0.9 0.054 13.4 0.9 2.7 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 CUU98837.1 - 1.4e-17 62.1 0.2 2.4e-05 23.9 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CUU98837.1 - 5.6e-17 59.9 0.7 1.3e-06 27.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CUU98837.1 - 1.8e-16 60.3 2.9 6.8e-08 32.9 0.5 3.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU98837.1 - 1.2e-11 43.5 0.1 8.1e-05 21.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CUU98837.1 - 6.7e-06 25.9 0.4 0.0016 18.2 0.1 3.9 2 1 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CUU98837.1 - 4.6e-05 23.7 0.1 0.00036 20.8 0.1 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CUU98837.1 - 0.00045 20.1 0.1 0.017 15.1 0.1 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CUU98837.1 - 0.0077 16.4 0.0 0.021 15.0 0.0 1.8 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_9 PF14658.6 CUU98837.1 - 0.012 15.9 0.0 0.09 13.1 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain 2Fe-2S_thioredx PF01257.19 CUU98837.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Caleosin PF05042.13 CUU98837.1 - 0.035 14.0 0.1 14 5.6 0.1 2.6 1 1 2 3 3 3 0 Caleosin related protein Lip_prot_lig_C PF10437.9 CUU98837.1 - 0.048 13.7 0.0 0.24 11.4 0.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF2087 PF09860.9 CUU98837.1 - 0.13 12.4 0.6 3.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) ABC_tran_CTD PF16326.5 CUU98838.1 - 0.018 15.3 0.2 0.018 15.3 0.2 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain UPF0184 PF03670.13 CUU98838.1 - 0.033 14.6 0.7 6.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF948 PF06103.11 CUU98838.1 - 0.082 13.2 0.3 0.27 11.5 0.3 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.8 CUU98838.1 - 0.087 12.9 0.1 0.3 11.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 CUU98838.1 - 0.22 11.6 1.3 0.53 10.3 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 CUU98838.1 - 0.76 10.0 5.3 0.8 10.0 0.9 2.6 2 0 0 2 2 2 0 Haemolysin XhlA CorA PF01544.18 CUU98838.1 - 2.5 7.3 6.6 1.5 8.1 1.6 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein EF-hand_6 PF13405.6 CUU98839.1 - 1.4e-17 62.1 0.2 2.4e-05 23.9 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CUU98839.1 - 5.6e-17 59.9 0.7 1.3e-06 27.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CUU98839.1 - 1.8e-16 60.3 2.9 6.8e-08 32.9 0.5 3.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU98839.1 - 1.2e-11 43.5 0.1 8.1e-05 21.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CUU98839.1 - 6.7e-06 25.9 0.4 0.0016 18.2 0.1 3.9 2 1 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CUU98839.1 - 4.6e-05 23.7 0.1 0.00036 20.8 0.1 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CUU98839.1 - 0.00045 20.1 0.1 0.017 15.1 0.1 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CUU98839.1 - 0.0077 16.4 0.0 0.021 15.0 0.0 1.8 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_9 PF14658.6 CUU98839.1 - 0.012 15.9 0.0 0.09 13.1 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain 2Fe-2S_thioredx PF01257.19 CUU98839.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Caleosin PF05042.13 CUU98839.1 - 0.035 14.0 0.1 14 5.6 0.1 2.6 1 1 2 3 3 3 0 Caleosin related protein Lip_prot_lig_C PF10437.9 CUU98839.1 - 0.048 13.7 0.0 0.24 11.4 0.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF2087 PF09860.9 CUU98839.1 - 0.13 12.4 0.6 3.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Telomerase_RBD PF12009.8 CUU98840.1 - 0.031 14.4 1.0 0.051 13.7 1.0 1.3 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain bZIP_1 PF00170.21 CUU98841.1 - 3e-11 43.3 13.5 4.3e-11 42.8 13.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CUU98841.1 - 1.6e-07 31.7 7.5 2.2e-07 31.3 7.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CUU98841.1 - 2.7e-07 30.6 14.1 4.1e-07 30.0 14.1 1.2 1 0 0 1 1 1 1 Basic region leucine zipper ASD2 PF08687.11 CUU98841.1 - 0.00035 20.2 1.7 0.00039 20.1 1.7 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 UPF0242 PF06785.11 CUU98841.1 - 0.002 18.3 1.6 0.0023 18.1 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus GCN5L1 PF06320.13 CUU98841.1 - 0.0055 16.9 1.0 0.0069 16.5 1.0 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) ZapB PF06005.12 CUU98841.1 - 0.0076 16.7 4.9 0.0076 16.7 4.9 1.7 2 0 0 2 2 2 1 Cell division protein ZapB Macoilin PF09726.9 CUU98841.1 - 0.019 13.6 5.7 0.021 13.4 5.7 1.0 1 0 0 1 1 1 0 Macoilin family Phlebovirus_NSM PF07246.11 CUU98841.1 - 0.023 14.1 1.7 0.029 13.7 1.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.9 CUU98841.1 - 0.034 14.2 6.0 0.052 13.6 6.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 CUU98841.1 - 0.04 13.8 3.6 0.09 12.7 3.6 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CUU98841.1 - 0.042 13.2 1.9 0.058 12.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 CUU98841.1 - 0.043 13.9 5.2 0.043 13.9 5.2 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation HAUS6_N PF14661.6 CUU98841.1 - 0.085 12.4 2.6 0.099 12.2 2.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.15 CUU98841.1 - 1.8 8.4 6.6 0.51 10.1 2.9 1.8 1 1 1 2 2 2 0 Septum formation initiator PND PF17949.1 CUU98842.1 - 0.0018 18.5 0.2 0.0024 18.1 0.2 1.2 1 0 0 1 1 1 1 FANCM pseudonuclease domain EloA-BP1 PF15870.5 CUU98845.1 - 0.00043 20.6 0.0 0.00058 20.2 0.0 1.2 1 0 0 1 1 1 1 ElonginA binding-protein 1 DSPc PF00782.20 CUU98848.1 - 6.1e-06 26.1 0.0 6.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Neur_chan_LBD PF02931.23 CUU98849.1 - 1.1e-47 162.3 1.4 1.5e-47 161.8 1.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CUU98849.1 - 1.3e-14 54.9 0.0 1.8e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Sulfotransfer_2 PF03567.14 CUU98850.1 - 6.8e-17 62.2 2.5 9.3e-17 61.8 2.5 1.2 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 CUU98850.1 - 0.061 12.2 2.8 0.15 10.9 2.8 1.6 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase Guanylate_cyc PF00211.20 CUU98851.1 - 8.1e-120 397.1 0.0 1.6e-58 197.4 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CUU98851.1 - 3.6e-51 173.9 0.0 3e-24 85.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CUU98851.1 - 7.8e-46 156.6 0.0 1.6e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain DEAD PF00270.29 CUU98851.1 - 3.7e-45 153.8 0.0 9.3e-45 152.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CUU98851.1 - 1.2e-09 38.5 0.1 3.1e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNOBA PF07701.14 CUU98851.1 - 1.7e-06 27.6 7.1 0.011 15.2 0.8 2.7 2 0 0 2 2 2 2 Heme NO binding associated DUF4370 PF14290.6 CUU98851.1 - 0.00013 22.0 0.1 0.92 9.3 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4370) RE_ApaLI PF09499.10 CUU98851.1 - 0.0068 16.1 0.7 4 7.1 0.1 2.3 2 0 0 2 2 2 2 ApaLI-like restriction endonuclease Colicin PF01024.19 CUU98851.1 - 0.011 15.7 6.8 0.96 9.3 0.1 3.0 4 0 0 4 4 4 0 Colicin pore forming domain DUF2723 PF11028.8 CUU98851.1 - 0.013 15.5 0.3 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) DUF3349 PF11829.8 CUU98851.1 - 0.029 15.1 0.0 22 5.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) RPN6_N PF18055.1 CUU98851.1 - 0.067 13.6 1.0 18 5.7 0.1 2.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain CR6_interact PF10147.9 CUU98851.1 - 0.12 12.1 3.8 7 6.3 0.3 2.4 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Packaging_FI PF14000.6 CUU98851.1 - 0.33 11.4 2.1 31 5.0 0.2 2.7 2 0 0 2 2 2 0 DNA packaging protein FI TipAS PF07739.13 CUU98851.1 - 0.5 10.9 3.8 58 4.3 0.0 4.0 3 2 0 3 3 3 0 TipAS antibiotic-recognition domain Fzo_mitofusin PF04799.13 CUU98851.1 - 2 7.9 5.0 22 4.5 0.4 2.7 2 0 0 2 2 2 0 fzo-like conserved region DUF913 PF06025.12 CUU98852.1 - 0.11 11.4 2.6 0.14 11.1 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA PF00004.29 CUU98853.1 - 4.3e-15 56.3 0.0 1.4e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 CUU98853.1 - 1.6e-11 44.2 0.2 3.2e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 AAA lid domain Cdc6_C PF09079.11 CUU98853.1 - 7.9e-10 38.6 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 CUU98853.1 - 7.7e-07 29.5 0.0 2.3e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CUU98853.1 - 0.00029 21.2 2.1 0.0017 18.8 0.4 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 CUU98853.1 - 0.00091 18.6 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CUU98853.1 - 0.02 15.2 0.3 0.079 13.3 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CUU98853.1 - 0.084 13.4 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CUU98853.1 - 0.14 12.0 0.0 0.46 10.4 0.0 1.9 2 1 0 2 2 2 0 NACHT domain EF-hand_1 PF00036.32 CUU98854.1 - 5.2e-12 44.4 10.6 1.1e-06 27.7 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CUU98854.1 - 5.6e-12 45.3 7.4 2.5e-08 33.6 0.0 4.4 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 CUU98854.1 - 8.1e-11 40.9 8.1 1.3e-05 24.7 0.2 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CUU98854.1 - 2.4e-10 40.7 3.5 3.9e-05 24.0 0.1 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CUU98854.1 - 6.8e-10 38.0 5.6 0.00026 20.3 1.6 3.0 2 0 0 2 2 2 2 EF hand Mito_carr PF00153.27 CUU98854.1 - 4.2e-09 36.2 0.1 2.1e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial carrier protein EF-hand_4 PF12763.7 CUU98854.1 - 5.1e-06 26.4 0.3 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CUU98854.1 - 0.1 12.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain BTG PF07742.12 CUU98856.1 - 9.6e-25 86.7 0.0 1.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 BTG family EMC3_TMCO1 PF01956.16 CUU98858.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Phosphorylase PF00343.20 CUU98860.1 - 1.2e-260 866.8 0.1 1.4e-260 866.5 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF2607 PF10795.9 CUU98861.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) FERM_N PF09379.10 CUU98863.1 - 1e-12 47.8 0.0 2.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.6 CUU98863.1 - 5.3e-10 39.0 10.1 5.3e-10 39.0 10.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CUU98863.1 - 7.5e-05 22.5 9.8 0.00024 20.9 9.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CUU98863.1 - 0.00076 19.3 6.4 0.0023 17.8 5.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CUU98863.1 - 0.017 14.9 10.3 0.038 13.9 10.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CUU98863.1 - 0.02 14.9 11.1 0.02 14.9 11.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CUU98863.1 - 0.025 14.6 4.0 0.025 14.6 4.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CUU98863.1 - 0.055 13.6 8.0 0.17 12.0 8.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2239 PF09998.9 CUU98863.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) Fumble PF03630.14 CUU98866.1 - 1.6e-175 583.1 0.2 1.7e-117 392.3 0.0 2.2 2 0 0 2 2 2 2 Fumble DUF89 PF01937.19 CUU98866.1 - 1.2e-21 77.1 0.1 1.2e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF89 RNR_Alpha PF17975.1 CUU98866.1 - 0.00047 20.6 0.8 1.6 9.3 0.1 2.5 2 0 0 2 2 2 2 Ribonucleotide reductase alpha domain DUF3156 PF11354.8 CUU98866.1 - 0.0021 18.0 0.1 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3156) TFR_dimer PF04253.15 CUU98866.1 - 0.04 14.0 0.1 20 5.3 0.0 3.0 2 2 0 2 2 2 0 Transferrin receptor-like dimerisation domain DUF433 PF04255.14 CUU98866.1 - 0.04 13.8 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF433) PAH PF02671.21 CUU98866.1 - 0.06 13.5 0.2 22 5.3 0.0 2.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat MTCP1 PF08991.10 CUU98866.1 - 0.12 12.6 2.3 17 5.7 0.2 2.8 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type RNase_H PF00075.24 CUU98867.1 - 0.00018 21.7 0.1 0.00021 21.5 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CUU98867.1 - 0.0047 16.7 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4900 PF16241.5 CUU98868.1 - 0.093 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4900) AAA_lid_3 PF17862.1 CUU98872.1 - 7e-07 29.0 0.2 2e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 CUU98872.1 - 0.0032 17.4 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain CAF1 PF04857.20 CUU98872.1 - 0.011 15.0 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease SAM_Ste50p PF09235.10 CUU98872.1 - 0.071 13.4 0.2 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Cys_rich_CPXG PF14255.6 CUU98875.1 - 0.0067 16.3 0.4 0.023 14.6 0.1 2.1 2 0 0 2 2 2 1 Cysteine-rich CPXCG Kp4 PF09044.10 CUU98875.1 - 0.042 13.9 3.0 0.28 11.3 0.9 2.1 1 1 1 2 2 2 0 Kp4 DUF1922 PF09082.10 CUU98875.1 - 0.057 13.7 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Zn-ribbon_8 PF09723.10 CUU98875.1 - 0.13 12.4 0.6 0.13 12.4 0.6 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 CUU98875.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 CUU98875.1 - 0.29 10.6 5.1 0.81 9.2 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 CUU98875.1 - 0.34 10.7 2.9 4.5 7.1 0.5 2.4 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 CUU98875.1 - 0.38 10.8 6.4 0.97 9.5 4.3 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 CUU98875.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-UBR PF02207.20 CUU98875.1 - 2.5 8.3 10.0 0.13 12.4 2.5 2.1 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RNase_P_p30 PF01876.16 CUU98878.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit p30 DUF1129 PF06570.11 CUU98879.1 - 0.038 13.5 0.9 0.053 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Polysacc_synt_C PF14667.6 CUU98879.1 - 0.061 13.4 2.1 0.1 12.7 2.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PDZ_1 PF12812.7 CUU98881.1 - 0.16 12.0 0.0 0.72 9.9 0.0 2.0 3 0 0 3 3 3 0 PDZ-like domain DUF948 PF06103.11 CUU98883.1 - 0.088 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 CUU98884.1 - 3.4e-33 114.1 5.8 1.6e-10 41.4 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU98884.1 - 2.2e-30 104.6 6.9 8.8e-13 48.5 0.2 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CUU98884.1 - 8.6e-30 101.9 12.9 2.3e-07 31.0 0.2 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 CUU98884.1 - 2.3e-25 88.3 2.6 3.6e-08 33.5 0.1 6.5 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU98884.1 - 6.4e-21 72.2 10.8 0.0039 17.6 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Wbp11 PF09429.10 CUU98885.1 - 1.9e-19 69.8 8.3 1.9e-19 69.8 8.3 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 FAM24 PF15193.6 CUU98885.1 - 0.1 13.4 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 FAM24 family PhoU PF01895.19 CUU98885.1 - 0.19 12.2 0.4 0.19 12.2 0.4 1.8 2 1 0 2 2 2 0 PhoU domain Wbp11 PF09429.10 CUU98886.1 - 2.2e-18 66.4 8.3 2.2e-18 66.4 8.3 2.3 2 0 0 2 2 2 1 WW domain binding protein 11 ASC PF00858.24 CUU98887.1 - 6.7e-16 58.3 8.6 8.7e-16 57.9 8.6 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel RNase_H PF00075.24 CUU98888.1 - 1.4e-07 31.7 0.1 6.2e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 RNase H bHLH-MYC_N PF14215.6 CUU98888.1 - 0.09 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Spermine_synth PF01564.17 CUU98889.1 - 4e-59 199.2 0.0 6.2e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CUU98889.1 - 6.8e-23 80.3 0.1 1.3e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CUU98889.1 - 2.1e-05 25.1 0.0 0.00016 22.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CUU98889.1 - 7.8e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CUU98889.1 - 0.0022 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CUU98889.1 - 0.0025 18.5 0.0 0.0049 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PH PF00169.29 CUU98890.1 - 5.4e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 PH domain LAMTOR PF15454.6 CUU98890.1 - 0.17 12.5 4.0 0.77 10.4 0.6 3.4 3 0 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Dor1 PF04124.12 CUU98891.1 - 0.0015 17.3 0.1 0.0028 16.4 0.1 1.4 1 0 0 1 1 1 1 Dor1-like family Syndecan PF01034.20 CUU98892.1 - 0.021 14.7 1.1 0.056 13.4 1.1 1.7 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 CUU98892.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TMF_TATA_bd PF12325.8 CUU98893.1 - 9.6e-21 74.1 10.3 6.2e-19 68.3 1.8 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 CUU98893.1 - 0.0034 17.4 24.9 0.022 14.8 6.9 4.0 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 HAP1_N PF04849.13 CUU98893.1 - 0.0036 16.6 15.5 0.19 10.9 14.7 2.8 1 1 0 1 1 1 1 HAP1 N-terminal conserved region IFT57 PF10498.9 CUU98893.1 - 0.0071 15.4 7.9 0.17 10.8 0.1 2.9 3 0 0 3 3 3 2 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 CUU98893.1 - 0.0085 16.1 2.8 0.0085 16.1 2.8 3.1 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 CUU98893.1 - 0.011 14.9 1.5 0.011 14.9 1.5 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF4140 PF13600.6 CUU98893.1 - 0.017 15.5 10.4 1.1 9.7 0.2 3.8 2 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.10 CUU98893.1 - 0.02 15.3 5.6 1 9.8 0.2 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) YabA PF06156.13 CUU98893.1 - 0.025 15.2 10.8 0.26 11.9 0.4 3.1 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_N PF10481.9 CUU98893.1 - 0.045 13.4 8.3 0.091 12.4 2.3 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain BRE1 PF08647.11 CUU98893.1 - 0.047 13.8 0.2 0.047 13.8 0.2 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CUU98893.1 - 0.052 13.8 0.3 0.052 13.8 0.3 3.1 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 CUU98893.1 - 0.061 13.7 14.2 0.25 11.7 0.6 4.0 3 1 1 4 4 4 0 Csm1 N-terminal domain Fez1 PF06818.15 CUU98893.1 - 0.094 13.2 12.0 2.8 8.3 6.6 2.4 2 1 0 2 2 2 0 Fez1 DUF4201 PF13870.6 CUU98893.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 CUU98893.1 - 0.12 12.5 2.3 2 8.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TSNAXIP1_N PF15739.5 CUU98893.1 - 0.13 12.7 10.3 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Filament PF00038.21 CUU98893.1 - 0.13 11.9 12.7 0.79 9.2 0.2 3.0 1 1 0 3 3 3 0 Intermediate filament protein Vir_act_alpha_C PF10400.9 CUU98893.1 - 0.13 13.0 10.1 0.54 11.0 1.0 3.1 3 0 0 3 3 3 0 Virulence activator alpha C-term HIP1_clath_bdg PF16515.5 CUU98893.1 - 0.13 12.9 0.3 0.13 12.9 0.3 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 CUU98893.1 - 0.21 12.2 9.7 7.3 7.2 0.9 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal GrpE PF01025.19 CUU98893.1 - 0.21 11.2 9.6 1 9.0 0.3 3.0 3 0 0 3 3 3 0 GrpE Spc7 PF08317.11 CUU98893.1 - 0.35 9.7 13.4 0.1 11.4 0.6 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF641 PF04859.12 CUU98893.1 - 0.38 11.1 7.2 3.2 8.1 0.1 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) zf-C4H2 PF10146.9 CUU98893.1 - 0.63 10.3 4.1 0.4 11.0 0.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein SOGA PF11365.8 CUU98893.1 - 0.8 10.9 13.4 1.4 10.1 7.1 2.9 2 2 0 2 2 2 0 Protein SOGA PRKG1_interact PF15898.5 CUU98893.1 - 1.3 10.0 16.1 18 6.3 0.2 3.9 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 CUU98893.1 - 1.4 9.0 12.9 0.33 11.0 0.7 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding COG5 PF10392.9 CUU98893.1 - 1.6 8.9 10.3 0.54 10.4 0.2 2.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 LapA_dom PF06305.11 CUU98893.1 - 1.7 8.6 3.3 7 6.6 0.2 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SlyX PF04102.12 CUU98893.1 - 2 9.1 9.7 5.5 7.7 0.3 3.1 3 0 0 3 3 3 0 SlyX ABC_tran_CTD PF16326.5 CUU98893.1 - 2.2 8.6 13.2 0.53 10.6 1.6 3.0 3 1 0 3 3 3 0 ABC transporter C-terminal domain DLP_helical PF18709.1 CUU98893.1 - 2.3 7.3 6.2 4.1 6.5 0.2 2.4 3 0 0 3 3 3 0 Dynamin-like helical domain bZIP_1 PF00170.21 CUU98893.1 - 2.3 8.4 16.0 1.4 9.1 1.0 4.1 3 2 2 5 5 5 0 bZIP transcription factor Atg14 PF10186.9 CUU98893.1 - 2.4 7.2 11.2 0.28 10.2 1.0 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 CUU98893.1 - 2.8 8.4 6.7 27 5.2 1.7 3.4 3 1 0 3 3 2 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 CUU98893.1 - 4.3 7.3 11.8 3.2 7.7 0.1 3.6 3 1 0 3 3 3 0 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 CUU98893.1 - 4.5 6.8 11.4 0.85 9.2 1.3 2.8 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TerB_C PF15615.6 CUU98893.1 - 6.2 7.1 9.0 52 4.1 9.0 2.2 1 1 0 1 1 1 0 TerB-C domain DivIC PF04977.15 CUU98893.1 - 6.4 6.6 12.2 0.68 9.7 0.2 3.3 3 1 0 3 3 3 0 Septum formation initiator Peptidase_M3_N PF08439.10 CUU98893.1 - 7 7.0 8.4 3 8.2 0.2 2.8 3 0 0 3 3 2 0 Oligopeptidase F ZapB PF06005.12 CUU98893.1 - 9 6.8 23.2 34 5.0 0.9 3.1 2 1 0 2 2 2 0 Cell division protein ZapB Mago_nashi PF02792.14 CUU98896.1 - 8.5e-57 191.3 0.0 2.4e-56 189.8 0.0 1.7 1 0 0 1 1 1 1 Mago nashi protein Lentiviral_Tat PF02998.14 CUU98896.1 - 0.14 12.2 0.3 5.5 7.1 0.0 3.0 2 1 0 2 2 2 0 Lentiviral Tat protein DUF4951 PF16309.5 CUU98897.1 - 0.00037 20.5 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 2 Domian of unknown function (DUF4951) Methyltransf_10 PF05971.12 CUU98897.1 - 0.1 11.9 0.2 5.7 6.2 0.0 2.0 1 1 0 2 2 2 0 RNA methyltransferase Torsin PF06309.11 CUU98897.1 - 0.16 12.1 0.0 15 5.7 0.0 2.2 1 1 1 2 2 2 0 Torsin LPG_synthase_TM PF03706.13 CUU98899.1 - 0.02 14.5 0.4 5.6 6.4 0.1 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region TRPM_tetra PF16519.5 CUU98899.1 - 0.051 13.7 0.0 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF2996 PF11210.8 CUU98899.1 - 0.17 12.4 1.9 1.1e+02 3.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2996) ATP-gua_PtransN PF02807.15 CUU98899.1 - 0.35 11.3 3.1 28 5.2 0.1 3.1 3 0 0 3 3 3 0 ATP:guanido phosphotransferase, N-terminal domain Pkinase PF00069.25 CUU98902.1 - 3.7e-55 187.1 0.1 5.2e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98902.1 - 6.5e-23 81.3 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CUU98902.1 - 0.0019 17.6 0.1 0.003 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CUU98902.1 - 0.0022 16.8 0.1 0.0035 16.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CUU98902.1 - 0.0026 17.7 0.1 0.0038 17.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Spa1_C PF18218.1 CUU98902.1 - 0.037 14.4 0.3 17 5.9 0.0 3.5 3 1 1 4 4 4 0 Lantibiotic immunity protein Spa1 C-terminal domain Kelch_1 PF01344.25 CUU98906.1 - 0.00064 19.3 0.6 0.086 12.4 0.0 3.1 2 2 0 2 2 2 2 Kelch motif Band_7 PF01145.25 CUU98908.1 - 1.1e-29 103.7 0.8 1.6e-29 103.2 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CUU98908.1 - 0.0014 18.4 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.25 CUU98909.1 - 1.1e-29 103.7 0.8 1.6e-29 103.2 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CUU98909.1 - 0.0014 18.4 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Lebercilin PF15619.6 CUU98910.1 - 0.00052 19.7 8.9 0.00052 19.7 8.9 4.7 4 1 0 4 4 3 2 Ciliary protein causing Leber congenital amaurosis disease JIP_LZII PF16471.5 CUU98910.1 - 0.00077 19.6 32.3 0.0028 17.8 0.3 6.1 5 1 1 6 6 6 2 JNK-interacting protein leucine zipper II Leu_zip PF15294.6 CUU98910.1 - 0.0017 17.9 2.3 0.0017 17.9 2.3 5.0 1 1 3 5 5 5 2 Leucine zipper TolA_bind_tri PF16331.5 CUU98910.1 - 0.0069 16.4 0.8 0.0069 16.4 0.8 6.8 7 1 1 8 8 8 1 TolA binding protein trimerisation UPF0242 PF06785.11 CUU98910.1 - 0.0099 16.0 8.0 0.0099 16.0 8.0 4.6 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus DUF3802 PF12290.8 CUU98910.1 - 0.013 16.0 1.1 0.46 11.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Uso1_p115_C PF04871.13 CUU98910.1 - 0.017 15.5 15.5 0.017 15.5 15.5 5.0 3 1 1 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2312 PF10073.9 CUU98910.1 - 0.58 9.8 12.9 1.5 8.5 0.0 4.8 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) Herpes_BLRF2 PF05812.12 CUU98910.1 - 0.59 10.3 19.4 1.1 9.5 0.4 4.4 4 1 0 4 4 4 0 Herpesvirus BLRF2 protein PI_PP_I PF18363.1 CUU98910.1 - 2.5 8.3 5.5 64 3.8 0.2 4.1 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain bZIP_1 PF00170.21 CUU98910.1 - 2.9 8.0 37.9 0.39 10.8 3.4 5.5 5 0 0 5 5 5 0 bZIP transcription factor AROS PF15684.5 CUU98911.1 - 0.00071 20.1 1.0 0.0013 19.2 0.2 1.7 1 1 0 2 2 2 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Lebercilin PF15619.6 CUU98912.1 - 0.013 15.2 14.6 0.015 15.0 13.1 1.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1139 PF06599.11 CUU98912.1 - 0.031 13.7 3.5 0.041 13.3 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1139) DUF4472 PF14739.6 CUU98912.1 - 0.089 13.5 12.7 0.11 13.2 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Prefoldin_2 PF01920.20 CUU98912.1 - 0.17 11.9 11.4 3.6 7.6 11.3 2.5 1 1 0 1 1 1 0 Prefoldin subunit ZapB PF06005.12 CUU98912.1 - 0.21 12.1 16.9 0.18 12.3 4.8 2.7 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 CUU98912.1 - 0.23 11.9 12.2 0.16 12.4 7.1 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 CUU98912.1 - 0.23 11.3 17.4 0.38 10.6 17.4 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 CUU98912.1 - 0.26 11.8 21.0 0.27 11.8 12.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 CUU98912.1 - 0.58 10.2 16.9 2.6 8.1 4.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 CUU98912.1 - 0.6 10.2 4.9 1.5 8.9 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CUU98912.1 - 1.4 9.1 15.9 2.7 8.2 3.1 2.2 1 1 1 2 2 2 0 Tropomyosin like SDF PF00375.18 CUU98914.1 - 1.1e-73 248.5 39.4 1.5e-73 248.1 39.4 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Mito_morph_reg PF14972.6 CUU98914.1 - 0.043 13.4 1.4 0.095 12.3 1.3 1.6 1 1 0 1 1 1 0 Mitochondrial morphogenesis regulator SDF PF00375.18 CUU98915.1 - 1.4e-76 258.1 37.1 1.7e-76 257.8 37.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FtsX PF02687.21 CUU98915.1 - 0.046 14.2 0.3 0.046 14.2 0.3 5.6 4 1 1 5 5 5 0 FtsX-like permease family Mito_morph_reg PF14972.6 CUU98915.1 - 0.19 11.3 0.6 0.42 10.2 0.6 1.5 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator SDF PF00375.18 CUU98916.1 - 1.5e-77 261.2 37.5 1.9e-77 260.9 37.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FtsX PF02687.21 CUU98916.1 - 0.064 13.7 0.1 0.064 13.7 0.1 5.6 2 1 2 4 4 4 0 FtsX-like permease family Mito_morph_reg PF14972.6 CUU98916.1 - 0.16 11.6 0.5 0.44 10.1 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator DUF1825 PF08855.10 CUU98919.1 - 0.024 14.6 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) DUF4071 PF13281.6 CUU98920.1 - 1.5e-122 409.3 0.2 2.6e-122 408.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4071) Pkinase PF00069.25 CUU98920.1 - 1e-62 211.9 0.0 2.4e-62 210.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU98920.1 - 6.1e-45 153.5 0.0 1.1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CUU98920.1 - 3.7e-06 26.0 0.0 1.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CUU98920.1 - 0.00015 21.2 0.0 0.00034 20.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Citrate_ly_lig PF08218.11 CUU98920.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain CREPT PF16566.5 CUU98920.1 - 0.19 11.9 2.8 0.74 10.0 1.8 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Adeno_E3_CR2 PF02439.15 CUU98921.1 - 1.1 9.1 4.8 0.19 11.5 0.4 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Peptidase_M50 PF02163.22 CUU98922.1 - 8.7e-19 67.8 0.0 5.7e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 CUU98922.1 - 0.035 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain FERM_C PF09380.10 CUU98923.1 - 2e-19 69.8 0.0 4.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CUU98923.1 - 5.2e-11 42.3 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.18 CUU98923.1 - 2e-10 41.1 0.0 2.3e-06 28.0 0.0 2.7 1 1 1 2 2 2 2 FERM central domain FA PF08736.11 CUU98923.1 - 0.055 13.6 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 FERM adjacent (FA) Snf7 PF03357.21 CUU98924.1 - 8.2e-15 54.8 12.4 1.1e-14 54.4 12.4 1.2 1 0 0 1 1 1 1 Snf7 FliG_N PF14842.6 CUU98924.1 - 0.0041 17.6 1.1 0.0041 17.6 1.1 1.9 2 0 0 2 2 2 1 FliG N-terminal domain Ist1 PF03398.14 CUU98924.1 - 0.015 15.3 7.4 0.03 14.2 7.4 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Peptidase_M2 PF01401.18 CUU98924.1 - 0.068 11.8 7.6 0.081 11.5 7.6 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF3275 PF11679.8 CUU98924.1 - 0.098 12.6 1.6 0.14 12.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF1779 PF08680.10 CUU98924.1 - 0.23 11.6 6.3 0.33 11.1 6.3 1.2 1 0 0 1 1 1 0 TATA-box binding HSCB_C PF07743.13 CUU98924.1 - 6.6 7.3 9.5 1.2 9.6 1.2 3.2 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain LRR_6 PF13516.6 CUU98925.1 - 4.5e-11 41.9 13.7 0.63 10.2 0.1 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 CUU98925.1 - 7.4e-10 38.9 7.8 0.58 10.7 0.1 5.9 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) F-box PF00646.33 CUU98925.1 - 8.6e-10 38.2 0.5 3.2e-09 36.4 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CUU98925.1 - 1.7e-09 37.4 1.0 1.7e-09 37.4 1.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 CUU98925.1 - 0.00012 22.1 18.3 1.3 9.8 0.0 8.2 8 0 0 8 8 8 2 Leucine Rich Repeat F-box_4 PF15966.5 CUU98925.1 - 0.00016 21.5 0.0 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 CUU98925.1 - 0.00022 20.9 7.0 2.6 7.8 0.1 5.1 4 2 0 4 4 4 3 Leucine rich repeat FOP_dimer PF09398.10 CUU98927.1 - 4.9e-07 29.9 0.1 1.8e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 CUU98927.1 - 0.0009 18.2 0.1 0.0045 16.0 0.0 2.0 2 0 0 2 2 2 1 LisH LisH PF08513.11 CUU98927.1 - 0.1 12.6 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 LisH SRI PF08236.11 CUU98929.1 - 1.7e-12 47.4 0.0 4.4e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 CUU98929.1 - 0.017 15.2 5.9 0.017 15.2 5.9 2.4 2 0 0 2 2 2 0 WW domain Herpes_glycop PF01528.16 CUU98930.1 - 0.036 12.9 1.2 0.037 12.9 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Inositol_P PF00459.25 CUU98932.1 - 8.5e-22 77.9 2.2 9.7e-22 77.8 2.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TAF4 PF05236.14 CUU98933.1 - 1.3e-05 25.1 1.0 1.6e-05 24.8 1.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-U PF13097.6 CUU98933.1 - 0.064 13.2 0.6 0.077 13.0 0.6 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit SPRY PF00622.28 CUU98937.1 - 1.4e-21 76.8 0.1 3.8e-10 39.9 0.1 2.8 2 0 0 2 2 2 2 SPRY domain FERM_M PF00373.18 CUU98937.1 - 1.2e-17 64.4 0.0 4.7e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 FERM central domain FERM_C PF09380.10 CUU98937.1 - 1.2e-16 60.9 0.0 2.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CUU98937.1 - 4.7e-10 39.3 0.7 1.1e-09 38.1 0.7 1.7 1 0 0 1 1 1 1 FERM N-terminal domain RHINO PF15319.6 CUU98937.1 - 0.034 14.2 4.8 0.064 13.3 0.0 2.6 2 1 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF716 PF04819.12 CUU98938.1 - 2.7e-15 56.2 9.1 2.7e-15 56.2 9.1 2.3 2 1 0 2 2 2 1 Family of unknown function (DUF716) Mito_carr PF00153.27 CUU98939.1 - 1.6e-56 188.2 2.2 1.1e-22 79.7 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 CUU98939.1 - 0.014 14.6 1.1 1.7 7.8 0.0 3.2 3 1 1 4 4 4 0 Gammaproteobacterial serine protease PAX PF00292.18 CUU98940.1 - 2.9e-67 224.3 0.7 4.7e-67 223.6 0.7 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 CUU98940.1 - 6e-06 26.8 0.3 0.065 13.9 0.0 3.0 2 1 1 3 3 3 2 Homeodomain-like domain HTH_23 PF13384.6 CUU98940.1 - 1.5e-05 24.6 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Pkinase PF00069.25 CUU98941.1 - 3.9e-05 23.1 0.1 3.9e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CUU98941.1 - 0.025 13.9 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.25 CUU98942.1 - 0.017 14.6 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Methylase_S PF01420.19 CUU98943.1 - 0.015 15.5 0.0 0.018 15.3 0.0 1.0 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Innexin PF00876.18 CUU98951.1 - 3.7e-178 592.2 30.1 5e-84 282.6 3.1 3.6 2 1 1 3 3 3 3 Innexin XisI PF08869.11 CUU98951.1 - 9.9e-06 25.9 1.4 6.2 7.2 0.0 4.2 3 0 0 3 3 3 3 XisI protein Corona_NS2 PF04753.12 CUU98951.1 - 0.00015 22.3 0.1 19 5.9 0.0 3.5 3 0 0 3 3 3 3 Coronavirus non-structural protein NS2 KH_10 PF17905.1 CUU98951.1 - 0.0013 19.1 2.9 1.5 9.3 0.2 2.6 2 0 0 2 2 2 2 GLD-3 KH domain 5 DBD_Tnp_Mut PF03108.15 CUU98951.1 - 0.0089 16.0 1.5 57 3.8 0.0 4.2 5 0 0 5 5 5 0 MuDR family transposase HTH_27 PF13463.6 CUU98951.1 - 0.028 14.9 0.0 17 6.0 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3278 PF11683.8 CUU98951.1 - 0.86 9.7 19.7 1.9 8.6 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Pap_E4 PF02711.14 CUU98951.1 - 1.1 10.3 9.7 10 7.1 1.5 2.6 2 0 0 2 2 2 0 E4 protein Ion_trans_2 PF07885.16 CUU98953.1 - 6.1e-34 115.8 15.6 1.1e-17 63.8 0.8 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CUU98953.1 - 1.9e-08 33.9 1.5 0.0037 16.5 0.0 2.3 1 1 1 2 2 2 2 Ion transport protein ASF1_hist_chap PF04729.13 CUU98955.1 - 1.8e-67 226.1 0.0 2.7e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Acyltransf_C PF16076.5 CUU98956.1 - 3.2e-10 40.0 0.2 1.2e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CUU98956.1 - 3.4e-05 23.5 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_2 PF07719.17 CUU98957.1 - 1.7e-07 30.8 0.7 0.17 12.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 CUU98957.1 - 5.1e-07 29.0 0.7 3.1e-06 26.5 0.3 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 CUU98957.1 - 1.1e-06 28.9 1.9 0.00014 22.1 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CUU98957.1 - 1.2e-06 28.3 2.1 0.048 13.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CUU98957.1 - 0.00012 21.7 2.6 0.35 10.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.9 CUU98957.1 - 0.0036 16.1 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Uds1 PF15456.6 CUU98957.1 - 0.16 12.1 2.4 0.23 11.6 0.2 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Presenilin PF01080.17 CUU98957.1 - 0.17 10.7 5.5 0.29 9.9 5.5 1.3 1 0 0 1 1 1 0 Presenilin TPR_10 PF13374.6 CUU98957.1 - 0.25 11.3 3.4 1.1 9.3 0.1 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CUU98957.1 - 0.57 10.3 2.2 27 5.1 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat RL10P_insert PF17777.1 CUU98958.1 - 4.1e-22 78.0 0.0 7.6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CUU98958.1 - 3.7e-19 68.7 0.6 6.7e-19 67.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 EGF_CA PF07645.15 CUU98958.1 - 5.3e-09 36.1 7.0 1.3e-08 34.9 7.0 1.7 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.7 CUU98958.1 - 4.7e-05 23.2 4.5 0.072 13.0 0.8 2.7 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.27 CUU98958.1 - 0.00099 19.4 4.4 0.00099 19.4 4.4 2.2 1 1 0 1 1 1 1 EGF-like domain Plasmod_Pvs28 PF06247.11 CUU98958.1 - 0.0027 17.9 5.7 0.0063 16.8 5.7 1.6 1 0 0 1 1 1 1 Pvs28 EGF domain hEGF PF12661.7 CUU98958.1 - 0.0057 17.2 3.9 0.0057 17.2 3.9 2.4 3 0 0 3 3 1 1 Human growth factor-like EGF FXa_inhibition PF14670.6 CUU98958.1 - 0.0077 16.5 5.0 0.02 15.2 4.8 1.9 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 CUU98958.1 - 0.017 15.5 4.8 0.017 15.5 4.8 2.6 2 1 0 2 2 2 0 EGF-like domain EB PF01683.18 CUU98958.1 - 0.034 14.5 9.3 0.034 14.5 9.3 2.2 2 1 0 2 2 2 0 EB module EGF_MSP1_1 PF12946.7 CUU98958.1 - 0.13 12.4 5.4 0.31 11.1 5.4 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 CUU98958.1 - 1.1 9.5 10.1 0.16 12.2 4.6 2.3 2 1 0 2 2 2 0 EGF domain COMPASS-Shg1 PF05205.12 CUU98959.1 - 9.8e-10 39.1 0.7 2.8e-09 37.6 0.1 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Esterase PF00756.20 CUU98961.1 - 5.6e-50 170.3 0.0 8.5e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_C97 PF05903.14 CUU98961.1 - 1.2e-31 109.6 0.0 2.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Hydrolase_4 PF12146.8 CUU98961.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CUU98961.1 - 0.0041 16.6 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 CUU98961.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.9 CUU98961.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Peptidase_S9 PF00326.21 CUU98961.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family LRR_8 PF13855.6 CUU98962.1 - 3e-07 30.1 9.5 0.0014 18.4 1.0 2.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CUU98962.1 - 2.5e-05 24.5 10.6 0.0025 18.2 1.3 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CUU98962.1 - 0.075 13.6 8.9 15 6.6 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 CUU98962.1 - 0.86 9.1 3.4 2.6 7.5 2.2 1.9 1 1 1 2 2 2 0 Leucine-rich repeat Med14 PF08638.11 CUU98964.1 - 0.0024 17.3 2.0 0.074 12.5 0.5 2.1 2 0 0 2 2 2 2 Mediator complex subunit MED14 ADIP PF11559.8 CUU98964.1 - 0.11 12.6 0.6 0.11 12.6 0.6 2.6 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding A2M_BRD PF07703.14 CUU98965.1 - 2e-17 63.9 0.0 5.3e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 CUU98965.1 - 2.7e-11 43.8 0.0 2.5e-07 31.1 0.0 4.7 4 0 0 4 4 4 1 MG2 domain A2M PF00207.22 CUU98965.1 - 1.9e-09 37.2 0.0 9.6e-09 35.0 0.0 2.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG3 PF17791.1 CUU98965.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Macroglobulin domain MG3 Ldl_recept_a PF00057.18 CUU98965.1 - 0.008 16.4 5.9 0.015 15.5 5.9 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A NAD_kinase PF01513.21 CUU98966.1 - 1.1e-09 37.9 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CUU98966.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CD36 PF01130.21 CUU98967.1 - 4e-70 236.7 2.5 5.6e-70 236.2 2.5 1.1 1 0 0 1 1 1 1 CD36 family PCI PF01399.27 CUU98969.1 - 5.2e-18 65.5 0.8 8.2e-18 64.8 0.8 1.3 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 CUU98969.1 - 1e-16 60.7 4.3 2.2e-16 59.7 4.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 CUU98969.1 - 0.0015 18.5 0.7 0.0059 16.6 0.3 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Fzo_mitofusin PF04799.13 CUU98969.1 - 0.058 12.9 2.4 0.051 13.1 0.7 1.7 1 1 0 1 1 1 0 fzo-like conserved region UEV PF05743.13 CUU98969.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 UEV domain RPN5_C PF18098.1 CUU98970.1 - 9.6e-17 60.8 4.3 2.1e-16 59.7 4.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 CUU98970.1 - 1.4e-16 60.9 0.3 2.1e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CUU98970.1 - 0.0014 18.7 1.1 0.005 16.8 0.4 2.3 1 1 2 3 3 3 1 CSN8/PSMD8/EIF3K family Fzo_mitofusin PF04799.13 CUU98970.1 - 0.047 13.2 0.7 0.047 13.2 0.7 1.9 1 1 1 2 2 2 0 fzo-like conserved region UEV PF05743.13 CUU98970.1 - 0.098 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 UEV domain FERM_N PF09379.10 CUU98973.1 - 2.5e-10 40.1 0.0 3.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 FERM N-terminal domain DNA_pol_A PF00476.20 CUU98975.1 - 5.1e-70 236.4 0.0 2.6e-69 234.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 CUU98975.1 - 5.6e-13 49.0 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CUU98975.1 - 8.4e-10 39.0 0.1 5.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Glyco_hydro_38C PF07748.13 CUU98976.1 - 1.9e-16 60.8 0.0 8.1e-14 52.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CUU98976.1 - 5.3e-13 48.9 0.1 9.1e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 Alpha mannosidase middle domain Kelch_4 PF13418.6 CUU98977.1 - 9.2e-11 41.6 0.2 1e-06 28.6 0.1 2.8 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CUU98977.1 - 1.3e-09 38.0 0.0 5.8e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CUU98977.1 - 3.8e-07 29.6 0.1 0.023 14.3 0.0 2.7 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CUU98977.1 - 2.6e-05 24.1 0.4 0.097 12.7 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CUU98977.1 - 0.00051 19.9 0.1 0.38 10.8 0.0 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CUU98977.1 - 0.0016 18.7 2.7 0.8 10.1 0.0 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain ECH_1 PF00378.20 CUU98978.1 - 2.4e-69 233.4 0.0 2.8e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CUU98978.1 - 4.7e-35 121.6 0.3 2e-29 103.1 0.1 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4522 PF15022.6 CUU98978.1 - 0.048 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Peptidase_S49 PF01343.18 CUU98978.1 - 0.092 12.7 0.1 8.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 RT_RNaseH PF17917.1 CUU98980.1 - 1.4e-20 73.5 0.3 3e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CUU98980.1 - 6.2e-20 71.1 0.1 1.2e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CUU98980.1 - 5.6e-11 42.4 1.4 1.2e-10 41.3 1.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CUU98980.1 - 2.1e-05 24.1 0.0 5.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Kelch_4 PF13418.6 CUU98984.1 - 3.7e-10 39.7 0.2 1.9e-08 34.2 0.1 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CUU98984.1 - 8.2e-10 38.1 0.0 6.4e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CUU98984.1 - 3.2e-09 36.8 0.2 3.1e-08 33.6 0.0 2.7 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CUU98984.1 - 4.3e-08 32.8 0.2 0.00013 21.8 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CUU98984.1 - 8.8e-07 29.1 0.1 4.6e-06 26.8 0.0 2.3 3 0 0 3 3 3 1 Galactose oxidase, central domain BTB PF00651.31 CUU98984.1 - 7.1e-06 26.2 0.0 0.00018 21.7 0.0 2.4 1 1 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CUU98984.1 - 0.00014 21.7 0.0 0.0005 20.0 0.0 2.0 1 0 0 1 1 1 1 Kelch motif QIL1 PF15884.5 CUU98985.1 - 5.9e-13 49.2 0.5 1.1e-12 48.3 0.5 1.5 1 0 0 1 1 1 1 MICOS complex subunit MIC13, QIL1 Exo_endo_phos_2 PF14529.6 CUU98986.1 - 2e-11 43.7 0.0 6.7e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Forkhead PF00250.18 CUU98988.1 - 2e-28 98.4 0.3 6.2e-28 96.9 0.1 1.9 2 0 0 2 2 2 1 Forkhead domain UPA PF17217.3 CUU98990.1 - 3e-29 101.7 0.0 6.4e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 UPA domain ZU5 PF00791.20 CUU98990.1 - 2.2e-25 88.9 0.0 8.2e-25 87.0 0.0 2.0 2 0 0 2 2 2 1 ZU5 domain Ig_3 PF13927.6 CUU98990.1 - 1.2e-12 48.2 0.1 4.2e-11 43.3 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CUU98990.1 - 1.2e-11 44.5 0.0 3.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CUU98990.1 - 1.8e-09 37.8 0.0 7e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Death PF00531.22 CUU98990.1 - 3.2e-09 36.8 0.2 7.8e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Death domain ig PF00047.25 CUU98990.1 - 1e-07 32.0 0.0 3.6e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CUU98990.1 - 0.00086 19.5 0.3 2.4 8.3 0.0 2.8 1 1 1 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CUU98990.1 - 0.053 13.6 0.0 0.24 11.5 0.0 2.2 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF1242 PF06842.12 CUU98992.1 - 0.025 14.4 12.4 0.063 13.1 12.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1242) ABC2_membrane_5 PF13346.6 CUU98992.1 - 0.033 13.7 3.5 0.036 13.6 3.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 7TMR-DISM_7TM PF07695.11 CUU98992.1 - 0.045 13.7 2.4 0.046 13.6 2.2 1.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.6 CUU98992.1 - 0.18 11.4 0.4 0.29 10.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pyr_redox_2 PF07992.14 CUU98993.1 - 1.3e-25 90.2 0.0 2.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CUU98993.1 - 0.00071 19.2 0.1 0.28 10.7 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CUU98993.1 - 0.018 15.0 1.4 5.6 6.9 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CUU98993.1 - 0.021 15.1 0.2 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CUU98993.1 - 0.042 14.4 0.1 13 6.4 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CUU98993.1 - 0.19 11.0 0.1 0.35 10.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family zf-ANAPC11 PF12861.7 CUU98994.1 - 1.2e-33 115.1 13.1 1.3e-33 114.9 13.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CUU98994.1 - 1.5e-19 70.0 17.2 2.2e-19 69.5 17.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CUU98994.1 - 3.2e-06 27.4 21.5 8e-05 22.9 20.7 2.4 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CUU98994.1 - 0.019 14.8 18.1 0.078 12.9 18.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CUU98994.1 - 0.052 13.6 12.1 0.041 13.9 10.2 1.8 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 CUU98994.1 - 0.075 12.8 1.3 0.075 12.8 1.3 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CUU98994.1 - 0.13 12.1 15.8 0.35 10.8 10.8 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 CUU98994.1 - 0.15 12.4 9.4 2.2 8.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-RING_11 PF17123.5 CUU98994.1 - 0.47 10.2 17.3 12 5.8 17.3 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CUU98994.1 - 0.62 10.1 21.0 18 5.4 21.7 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 CUU98994.1 - 0.82 9.5 9.2 1.7 8.5 9.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Opy2 PF09463.10 CUU98994.1 - 0.92 9.9 15.9 10 6.6 10.2 2.6 2 1 0 2 2 2 0 Opy2 protein FANCL_C PF11793.8 CUU98994.1 - 1.9 8.7 15.5 8.1 6.7 15.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HIT PF04438.16 CUU98994.1 - 2.5 8.0 12.8 0.73 9.8 7.6 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_2 PF13923.6 CUU98994.1 - 3.7 7.5 20.6 7.8 6.4 17.1 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CUU98994.1 - 4 7.1 17.3 0.072 12.7 8.9 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CUU98994.1 - 7.2 6.8 16.2 0.56 10.4 7.1 2.4 2 1 0 2 2 2 0 RING-variant domain HTH_24 PF13412.6 CUU98995.1 - 0.0025 17.3 0.1 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Transposase_1 PF01359.18 CUU98995.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Transposase (partial DDE domain) DUF4250 PF14056.6 CUU98995.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) NdhS PF11623.8 CUU98995.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Arg_repressor PF01316.21 CUU98995.1 - 0.16 11.7 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_24 PF13412.6 CUU98996.1 - 0.0025 17.3 0.1 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Transposase_1 PF01359.18 CUU98996.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Transposase (partial DDE domain) DUF4250 PF14056.6 CUU98996.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) NdhS PF11623.8 CUU98996.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Arg_repressor PF01316.21 CUU98996.1 - 0.16 11.7 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain RRM_1 PF00076.22 CUU98998.1 - 1.1e-71 236.7 3.1 1.6e-19 69.5 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CUU98998.1 - 9.7e-13 48.1 0.1 2.4e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CUU98998.1 - 2.8e-06 27.0 0.7 5.4 6.6 0.1 4.4 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CUU98998.1 - 1e-05 25.4 0.2 0.074 13.1 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CUU98998.1 - 7.2e-05 22.8 0.4 8.9 6.5 0.0 5.0 4 2 0 4 4 4 1 RNA recognition motif SET_assoc PF11767.8 CUU98998.1 - 0.00082 19.0 0.7 32 4.3 0.0 4.4 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 CUU98998.1 - 0.0015 18.5 5.7 3.1 7.9 0.2 4.7 4 1 1 5 5 5 1 RNA binding motif Limkain-b1 PF11608.8 CUU98998.1 - 0.0059 16.7 0.3 9.2 6.4 0.0 3.5 3 0 0 3 3 3 1 Limkain b1 RRM_occluded PF16842.5 CUU98998.1 - 0.012 15.5 0.3 79 3.2 0.0 4.3 5 0 0 5 5 5 0 Occluded RNA-recognition motif OB_RNB PF08206.11 CUU98998.1 - 0.27 10.9 4.7 87 2.9 0.0 4.3 4 0 0 4 4 4 0 Ribonuclease B OB domain gag-asp_proteas PF13975.6 CUU98999.1 - 0.15 12.6 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ion_trans PF00520.31 CUU99001.1 - 7.6e-148 490.4 83.1 1.8e-51 174.8 23.0 5.1 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.12 CUU99001.1 - 4.7e-14 51.9 64.5 0.0007 18.4 2.5 7.1 6 1 1 7 7 7 6 Polycystin cation channel Na_trans_assoc PF06512.13 CUU99001.1 - 2e-11 44.6 2.7 5.7e-11 43.1 0.3 2.6 2 1 0 2 2 2 1 Sodium ion transport-associated GPHH PF16905.5 CUU99001.1 - 0.00016 21.3 0.1 0.00072 19.3 0.0 2.1 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated CLTH PF10607.9 CUU99003.1 - 1.1e-11 44.9 0.4 2.4e-11 43.7 0.4 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain TPR_19 PF14559.6 CUU99003.1 - 0.022 15.3 0.0 0.086 13.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CUU99003.1 - 0.076 12.4 0.1 0.78 9.1 0.1 2.1 1 1 1 2 2 2 0 MalT-like TPR region Haspin_kinase PF12330.8 CUU99004.1 - 1.3e-33 116.4 0.0 2.6e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain HMG_box_2 PF09011.10 CUU99004.1 - 0.004 17.7 2.5 0.004 17.7 2.5 2.3 2 1 1 3 3 3 1 HMG-box domain HMG_box PF00505.19 CUU99004.1 - 0.019 15.4 3.0 0.049 14.0 3.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box APH PF01636.23 CUU99004.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4795 PF16043.5 CUU99004.1 - 0.2 11.2 5.0 0.055 13.1 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 CUU99004.1 - 0.22 11.7 10.7 0.096 12.9 7.6 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 CUU99004.1 - 0.85 10.0 5.7 0.13 12.6 0.4 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor A Pullulanase_Ins PF18494.1 CUU99006.1 - 0.089 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Pullulanase Ins domain YjbE PF11106.8 CUU99006.1 - 0.72 10.1 11.9 0.1 12.8 4.8 2.2 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE GDE_N PF12439.8 CUU99008.1 - 0.0039 16.6 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme N terminal Homeodomain PF00046.29 CUU99009.1 - 8.5e-14 51.1 0.5 1.4e-13 50.4 0.5 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 CUU99009.1 - 0.0048 16.7 0.1 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain E3_UFM1_ligase PF09743.9 CUU99009.1 - 0.073 12.7 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Furin-like PF00757.20 CUU99011.1 - 8.3e-21 74.4 72.4 1.3e-15 57.5 37.4 3.2 2 1 1 3 3 3 3 Furin-like cysteine rich region GF_recep_IV PF14843.6 CUU99011.1 - 4.6e-09 36.2 70.8 1.1e-05 25.3 7.4 5.3 3 1 1 4 4 4 3 Growth factor receptor domain IV Recep_L_domain PF01030.24 CUU99011.1 - 1.3e-07 31.7 0.1 4.2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Receptor L domain GAS2 PF02187.17 CUU99012.1 - 3e-25 88.1 0.9 4.4e-25 87.6 0.9 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain 7tm_1 PF00001.21 CUU99013.1 - 6.1e-16 58.5 0.8 6.6e-16 58.4 0.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CH PF00307.31 CUU99015.1 - 5e-23 81.4 3.3 3.6e-16 59.3 0.0 3.5 4 0 0 4 4 4 2 Calponin homology (CH) domain Spectrin PF00435.21 CUU99015.1 - 2.1e-05 24.9 15.8 0.42 11.1 0.2 5.5 4 1 1 5 5 5 3 Spectrin repeat DUF1940 PF09155.10 CUU99015.1 - 0.02 15.0 0.1 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) Mer2 PF09074.10 CUU99015.1 - 0.24 11.2 4.4 0.21 11.3 0.5 2.4 2 0 0 2 2 2 0 Mer2 zf-RVT PF13966.6 CUU99017.1 - 0.053 14.2 0.1 0.092 13.5 0.0 1.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase XRN_N PF03159.18 CUU99018.1 - 2.1e-100 335.1 0.0 3.2e-100 334.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CUU99018.1 - 2.7e-42 145.3 0.0 3.6e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain Thymopoietin PF08198.11 CUU99018.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Thymopoietin protein CLIP1_ZNF PF16641.5 CUU99018.1 - 0.075 12.9 1.9 0.2 11.6 1.9 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle Glyco_hydro_38N PF01074.22 CUU99019.1 - 3.4e-70 236.7 0.5 4.2e-70 236.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 CUU99019.1 - 8.5e-07 29.0 0.0 2.5e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Neuraminidase PF18413.1 CUU99020.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain Usp PF00582.26 CUU99021.1 - 7e-25 88.2 0.1 1.6e-24 87.0 0.1 1.6 1 1 0 1 1 1 1 Universal stress protein family Acetyltransf_1 PF00583.25 CUU99022.1 - 3.7e-16 59.4 0.1 4.7e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CUU99022.1 - 4.3e-11 43.1 0.0 5.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CUU99022.1 - 1.8e-10 40.8 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 CUU99022.1 - 0.004 15.8 0.0 0.13 10.8 0.0 2.1 1 1 1 2 2 2 2 Arginine N-succinyltransferase beta subunit Acetyltransf_CG PF14542.6 CUU99022.1 - 0.052 13.7 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2536 PF10750.9 CUU99022.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Importin_rep_4 PF18808.1 CUU99023.1 - 1.5e-26 92.5 3.1 1.9e-24 85.8 0.8 3.9 4 0 0 4 4 3 1 Importin repeat HEAT PF02985.22 CUU99023.1 - 2.7e-17 61.4 9.7 0.00016 21.7 0.0 8.3 9 0 0 9 9 7 4 HEAT repeat HEAT_2 PF13646.6 CUU99023.1 - 4.7e-15 55.7 2.5 1.1e-06 28.9 0.1 6.0 3 2 2 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.7 CUU99023.1 - 1.1e-13 51.6 0.0 8.1e-06 26.3 0.0 5.6 3 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CUU99023.1 - 2.8e-13 50.1 7.7 7.1e-07 29.6 0.0 7.0 8 0 0 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 CUU99023.1 - 5.9e-08 32.9 0.1 3.2e-05 24.0 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 CUU99023.1 - 5.3e-06 26.4 0.2 0.57 10.1 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 CUU99023.1 - 3e-05 22.8 0.4 0.0012 17.5 0.0 3.0 1 1 2 3 3 3 2 Adaptin N terminal region IBN_N PF03810.19 CUU99023.1 - 3.4e-05 23.7 0.2 0.00032 20.6 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 CUU99023.1 - 0.00015 21.4 0.2 8 5.9 0.1 4.8 4 2 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 CUU99023.1 - 0.00075 18.7 0.1 0.0082 15.3 0.0 2.4 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Arm PF00514.23 CUU99023.1 - 0.00079 19.4 0.7 0.24 11.5 0.1 4.0 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 CUU99023.1 - 0.0011 18.7 2.1 1.1 8.8 0.0 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Gcn1_N PF12074.8 CUU99023.1 - 0.019 14.2 0.0 0.52 9.5 0.0 3.0 3 1 1 4 4 4 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF4042 PF13251.6 CUU99023.1 - 0.03 14.0 0.8 16 5.1 0.1 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 CUU99023.1 - 0.034 14.5 0.0 0.52 10.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion ASC PF00858.24 CUU99024.1 - 2.6e-43 148.6 0.7 4.2e-43 147.9 0.7 1.4 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Vps51 PF08700.11 CUU99027.1 - 1.7e-21 76.1 5.5 2.6e-21 75.5 2.8 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 CUU99027.1 - 1.3e-10 41.4 3.6 2.4e-10 40.6 3.6 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 CUU99027.1 - 4.7e-07 28.8 5.9 7e-07 28.2 5.9 1.2 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 CUU99027.1 - 0.00012 21.5 4.0 0.00022 20.6 4.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 CUU99027.1 - 0.00038 20.6 1.6 0.00038 20.6 1.6 3.1 3 2 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 CUU99027.1 - 0.0032 17.6 7.0 0.0033 17.5 1.3 3.1 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 ARL2_Bind_BART PF11527.8 CUU99027.1 - 0.018 15.2 0.1 0.018 15.2 0.1 2.5 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART RGS_DHEX PF18148.1 CUU99027.1 - 0.089 12.9 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Ribosomal_L3 PF00297.22 CUU99029.1 - 1.2e-175 583.9 12.8 5.2e-175 581.8 12.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L3 LIM PF00412.22 CUU99030.1 - 3.5e-54 180.9 56.0 7.5e-14 51.7 7.3 5.1 5 0 0 5 5 5 5 LIM domain DUF3268 PF11672.8 CUU99030.1 - 0.2 12.0 0.4 0.2 12.0 0.4 4.5 4 1 1 5 5 5 0 zinc-finger-containing domain CENP-B_N PF04218.13 CUU99032.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DnaJ PF00226.31 CUU99033.1 - 6.7e-22 77.4 1.0 1.6e-21 76.1 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CUU99033.1 - 2e-05 24.5 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CUU99033.1 - 0.085 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DnaJ PF00226.31 CUU99034.1 - 6.7e-22 77.4 1.0 1.6e-21 76.1 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CUU99034.1 - 2e-05 24.5 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CUU99034.1 - 0.085 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DnaJ PF00226.31 CUU99035.1 - 6.6e-22 77.4 1.0 1.6e-21 76.2 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 CUU99035.1 - 2e-05 24.5 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CUU99035.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family MRP-63 PF14978.6 CUU99036.1 - 0.0051 17.4 0.3 0.0076 16.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 C_Hendra PF16821.5 CUU99036.1 - 0.011 15.6 1.2 0.018 14.9 1.2 1.2 1 0 0 1 1 1 0 C protein from hendra and measles viruses N36 PF11438.8 CUU99036.1 - 0.54 10.1 2.9 0.61 10.0 1.3 2.0 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) DUF1700 PF08006.11 CUU99038.1 - 1.7 8.1 8.8 2 7.9 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) NARG2_C PF10505.9 CUU99039.1 - 2e-11 43.8 0.0 1e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus TAF1_subA PF14929.6 CUU99039.1 - 0.00013 21.6 2.0 0.012 15.0 2.0 2.9 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A DUF1754 PF08555.10 CUU99039.1 - 0.0049 17.6 13.7 0.016 16.0 4.8 2.6 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) DnaJ PF00226.31 CUU99040.1 - 9.5e-23 80.1 0.1 8.3e-10 38.7 0.0 2.7 2 0 0 2 2 2 2 DnaJ domain Thioredoxin PF00085.20 CUU99040.1 - 6.5e-13 48.6 0.0 6e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CUU99040.1 - 2.2e-05 24.0 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family EF-hand_6 PF13405.6 CUU99040.1 - 0.03 14.2 0.0 21 5.4 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain NUC205 PF08168.11 CUU99040.1 - 0.15 11.6 0.1 26 4.4 0.0 2.5 2 0 0 2 2 2 0 NUC205 domain DUF5063 PF16702.5 CUU99041.1 - 0.047 14.1 4.7 0.09 13.2 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) BLOC1_2 PF10046.9 CUU99041.1 - 0.24 11.7 8.8 0.15 12.4 1.9 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 CUU99041.1 - 0.39 10.0 8.6 0.25 10.7 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 CUU99041.1 - 0.61 10.1 7.3 6.8 6.7 3.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TetR_C_31 PF17940.1 CUU99041.1 - 0.86 9.8 5.4 1.3 9.3 3.5 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1993 PF09351.10 CUU99041.1 - 1.2 9.3 4.1 1.7 8.8 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) FliD_N PF02465.18 CUU99041.1 - 2 9.2 7.3 1.2 9.9 1.0 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_L30_N PF08079.12 CUU99041.1 - 8.2 6.8 14.0 0.4 11.0 0.4 2.7 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Zeta_toxin PF06414.12 CUU99042.1 - 0.00067 19.0 0.0 0.00078 18.8 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 CUU99042.1 - 0.00071 20.0 0.1 0.0012 19.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CUU99042.1 - 0.0068 16.8 0.0 0.011 16.1 0.0 1.3 1 1 1 2 2 2 1 AAA ATPase domain 6PF2K PF01591.18 CUU99042.1 - 0.013 14.8 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TniB PF05621.11 CUU99042.1 - 0.019 14.4 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein RuvB_N PF05496.12 CUU99042.1 - 0.02 14.6 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CUU99042.1 - 0.03 14.9 0.0 0.05 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CUU99042.1 - 0.061 13.6 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CUU99042.1 - 0.064 13.0 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CUU99042.1 - 0.067 13.5 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 CUU99042.1 - 0.084 13.0 0.0 0.084 13.0 0.0 1.1 1 0 0 1 1 1 0 Torsin KTI12 PF08433.10 CUU99042.1 - 0.086 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 CUU99042.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 CUU99042.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Parvo_NS1 PF01057.17 CUU99042.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 CUU99042.1 - 0.17 12.2 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CUU99042.1 - 0.19 11.9 0.0 0.31 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NPH-II PF12011.8 CUU99043.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 RNA helicase NPH-II LIM PF00412.22 CUU99044.1 - 2e-24 85.6 18.5 2.9e-14 53.0 9.6 2.2 2 0 0 2 2 2 2 LIM domain zf_UBZ PF18439.1 CUU99044.1 - 0.00023 20.7 16.9 0.14 11.8 0.9 4.4 4 0 0 4 4 4 3 Ubiquitin-Binding Zinc Finger DUF3268 PF11672.8 CUU99044.1 - 0.0059 16.9 0.9 0.0059 16.9 0.9 2.1 2 0 0 2 2 2 1 zinc-finger-containing domain zinc_ribbon_2 PF13240.6 CUU99044.1 - 0.0098 15.6 3.9 0.12 12.1 0.3 5.2 5 0 0 5 5 5 2 zinc-ribbon domain DUF2175 PF09943.9 CUU99044.1 - 0.053 13.8 0.5 0.053 13.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TNFR_c6 PF00020.18 CUU99044.1 - 0.23 11.9 0.5 0.23 11.9 0.5 4.6 3 1 1 4 4 4 0 TNFR/NGFR cysteine-rich region zf-dskA_traR PF01258.17 CUU99044.1 - 0.92 9.5 19.4 2 8.4 0.1 4.8 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger zf-ribbon_3 PF13248.6 CUU99044.1 - 0.92 9.0 12.6 1.2 8.6 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF2039 PF10217.9 CUU99044.1 - 1.9 8.9 20.8 0.09 13.1 7.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Ion_trans PF00520.31 CUU99045.1 - 7.2e-23 81.1 3.9 7.7e-23 81.0 3.9 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 CUU99046.1 - 7.1e-35 120.4 2.3 4e-22 78.6 1.0 2.1 1 1 1 2 2 2 2 Ion transport protein Inhibitor_I36 PF03995.13 CUU99046.1 - 0.00015 21.6 3.7 0.27 11.2 0.1 2.8 3 0 0 3 3 3 2 Peptidase inhibitor family I36 zf-CCHC_2 PF13696.6 CUU99046.1 - 0.14 12.0 2.5 13 5.7 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF3913 PF13052.6 CUU99046.1 - 0.14 12.5 0.2 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) Metallothio PF00131.20 CUU99046.1 - 0.42 10.8 4.8 10 6.3 0.0 2.5 3 0 0 3 3 3 0 Metallothionein Tme5_EGF_like PF09064.10 CUU99046.1 - 0.58 10.1 4.9 15 5.6 0.4 2.6 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Granulin PF00396.18 CUU99046.1 - 2.6 8.5 10.1 24 5.4 0.2 3.3 3 0 0 3 3 3 0 Granulin Lustrin_cystein PF14625.6 CUU99046.1 - 8.3 6.9 10.8 14 6.1 0.3 3.3 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Ion_trans PF00520.31 CUU99047.1 - 3e-34 118.3 1.3 3.3e-34 118.2 1.3 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CUU99047.1 - 1.1 7.8 4.8 0.44 9.2 0.4 1.9 1 1 0 2 2 2 0 Polycystin cation channel Rad51 PF08423.11 CUU99050.1 - 1.8e-32 112.6 0.8 2.1e-30 105.8 0.8 2.1 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 CUU99050.1 - 0.021 14.2 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 KaiC DUF2967 PF11179.8 CUU99051.1 - 0.026 12.6 1.5 0.032 12.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MRC1 PF09444.10 CUU99051.1 - 0.3 11.6 1.9 0.39 11.2 1.9 1.1 1 0 0 1 1 1 0 MRC1-like domain Collagen PF01391.18 CUU99052.1 - 3.7e-204 660.8 888.9 5.4e-09 35.7 28.7 29.7 6 5 22 28 28 28 27 Collagen triple helix repeat (20 copies) C4 PF01413.19 CUU99052.1 - 1e-62 209.4 3.5 6.6e-34 116.6 1.6 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Desmo_N PF06771.11 CUU99053.1 - 0.041 14.2 0.0 11 6.4 0.0 2.1 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus HNH PF01844.23 CUU99053.1 - 0.096 12.9 0.1 20 5.4 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease DUF4698 PF15769.5 CUU99054.1 - 0.038 13.1 1.5 0.042 12.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) OAD_gamma PF04277.13 CUU99054.1 - 0.11 13.2 0.0 1.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LRR_4 PF12799.7 CUU99055.1 - 4.7e-11 42.7 13.9 6.9e-08 32.7 3.5 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CUU99055.1 - 6e-08 32.3 9.3 1.3e-07 31.2 3.1 2.8 1 1 1 2 2 2 2 Leucine rich repeat Death PF00531.22 CUU99055.1 - 0.00047 20.3 0.0 0.045 13.9 0.0 2.4 2 0 0 2 2 2 1 Death domain LRR_1 PF00560.33 CUU99055.1 - 0.014 15.9 14.9 9.9 7.2 0.7 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CUU99055.1 - 1.2 9.4 8.1 9 6.6 0.3 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Sigma_M_inh PF17453.2 CUU99056.1 - 0.022 15.2 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-M inhibitor ESCRT-II PF05871.12 CUU99059.1 - 3.7e-48 163.3 1.1 1.5e-47 161.4 0.4 2.2 3 0 0 3 3 3 1 ESCRT-II complex subunit HLH PF00010.26 CUU99060.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 CUU99061.1 - 0.0001 22.2 0.0 0.00027 20.8 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4733 PF15878.5 CUU99062.1 - 3.9 8.0 5.4 10 6.7 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4733) Ribosomal_S8e PF01201.22 CUU99063.1 - 7.5e-107 353.3 5.4 1e-52 178.0 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S8e TnpB_IS66 PF05717.13 CUU99063.1 - 0.013 15.4 0.0 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 IS66 Orf2 like protein Mvb12 PF09452.10 CUU99063.1 - 0.045 14.2 0.0 21 5.6 0.0 2.6 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 ICAT PF06384.11 CUU99063.1 - 0.23 11.8 1.2 28 5.0 0.1 2.4 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT La PF05383.17 CUU99064.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 La domain MutL PF13941.6 CUU99065.1 - 0.17 10.4 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 MutL protein GPCR_chapero_1 PF11904.8 CUU99068.1 - 3.1e-42 145.1 0.3 4.7e-42 144.5 0.0 1.4 2 0 0 2 2 2 1 GPCR-chaperone UIM PF02809.20 CUU99068.1 - 0.19 11.7 0.1 0.19 11.7 0.1 4.4 4 0 0 4 4 4 0 Ubiquitin interaction motif Kinesin PF00225.23 CUU99069.1 - 2.3e-67 227.3 1.0 3.9e-67 226.6 1.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CUU99069.1 - 1.2e-34 119.4 0.0 1.2e-34 119.4 0.0 2.3 3 0 0 3 3 3 1 Microtubule binding GAS PF13851.6 CUU99069.1 - 0.039 13.3 29.3 0.67 9.3 14.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PEP-utilisers_N PF05524.13 CUU99069.1 - 0.28 11.4 2.2 0.9 9.7 2.2 2.0 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 CUU99069.1 - 1.7 9.3 21.4 17 6.1 0.0 4.5 2 1 2 4 4 4 0 Initiation control protein YabA bZIP_1 PF00170.21 CUU99069.1 - 8.7 6.5 25.2 4.2 7.5 3.6 4.6 2 1 3 5 5 5 0 bZIP transcription factor RabGAP-TBC PF00566.18 CUU99070.1 - 9.9e-50 169.2 1.5 1.9e-49 168.2 1.5 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 CUU99070.1 - 1.4e-08 35.5 0.0 3.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein TMF_TATA_bd PF12325.8 CUU99070.1 - 0.015 15.5 21.7 0.18 12.0 0.7 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CUU99070.1 - 0.059 13.4 3.6 0.13 12.3 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 CUU99070.1 - 0.077 13.4 4.2 4.1 7.9 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2935 PF11155.8 CUU99070.1 - 0.13 12.6 3.8 0.11 12.8 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Spc7 PF08317.11 CUU99070.1 - 0.55 9.1 20.7 0.17 10.8 0.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 CUU99070.1 - 2.7 8.2 16.3 1.4 9.1 5.3 3.5 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 CUU99070.1 - 3.9 6.7 8.5 1.3 8.3 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 CUU99070.1 - 6.5 6.8 20.8 2 8.5 0.6 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CUU99070.1 - 7 4.4 7.2 11 3.8 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol PF00940.19 CUU99071.1 - 9.8e-15 54.3 0.3 1.1e-14 54.1 0.3 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase DUF4187 PF13821.6 CUU99071.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) SPX PF03105.19 CUU99073.1 - 3 7.7 10.3 3.6 7.4 10.3 1.1 1 0 0 1 1 1 0 SPX domain NAD2 PF18782.1 CUU99075.1 - 0.014 15.5 0.2 0.38 10.9 0.0 2.2 1 1 1 2 2 2 0 Novel AID APOBEC clade 2 NAD2 PF18782.1 CUU99076.1 - 0.014 15.5 0.2 0.38 10.9 0.0 2.2 1 1 1 2 2 2 0 Novel AID APOBEC clade 2 Osmo_CC PF08946.10 CUU99077.1 - 0.051 13.8 0.4 0.2 11.9 0.4 2.1 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DNA_pol_B PF00136.21 CUU99078.1 - 2.3e-85 287.0 0.0 2.9e-84 283.4 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CUU99078.1 - 9.6e-21 74.3 0.0 2.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain GET2 PF08690.10 CUU99078.1 - 1.5 8.5 5.5 2.6 7.6 5.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Lactamase_B_2 PF12706.7 CUU99079.1 - 0.0092 15.5 0.0 0.048 13.2 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ANF_receptor PF01094.28 CUU99080.1 - 3e-71 240.4 0.0 3.8e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CUU99080.1 - 3.4e-05 23.7 0.2 5e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF2961 PF11175.8 CUU99080.1 - 0.054 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Mrr_cat PF04471.12 CUU99080.1 - 0.094 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease MatC_N PF07158.11 CUU99080.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus PIN_8 PF18476.1 CUU99083.1 - 0.088 12.7 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 PIN like domain HECT PF00632.25 CUU99085.1 - 1.8e-53 182.1 0.0 4.4e-53 180.8 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 CUU99085.1 - 6.1e-05 23.5 0.1 0.0015 19.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CUU99085.1 - 0.012 16.0 0.2 4.3 8.2 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 CUU99085.1 - 0.056 14.0 0.8 1.4 9.6 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) F5_F8_type_C PF00754.25 CUU99085.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain Ion_trans PF00520.31 CUU99086.1 - 2.3e-17 63.1 6.5 2.1e-16 59.9 6.5 2.0 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CUU99086.1 - 0.0001 22.2 9.5 0.1 12.6 4.2 2.3 2 0 0 2 2 2 2 Ion channel DUF3399 PF11879.8 CUU99086.1 - 0.085 13.2 0.1 0.085 13.2 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3399) DUF4954 PF16314.5 CUU99087.1 - 0.1 10.7 0.1 7.9 4.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) U-box PF04564.15 CUU99087.1 - 0.14 12.3 0.9 28 5.0 0.1 2.7 2 0 0 2 2 2 0 U-box domain APC_r PF05923.12 CUU99087.1 - 0.34 10.7 8.1 14 5.6 0.3 3.6 3 0 0 3 3 3 0 APC repeat YpmT PF17431.2 CUU99088.1 - 0.038 14.0 9.5 0.045 13.8 1.3 2.6 3 0 0 3 3 3 0 Uncharacterized YmpT-like M64_N PF16217.5 CUU99088.1 - 0.07 12.7 0.2 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Peptidase M64 N-terminus Hep_59 PF07052.11 CUU99089.1 - 2.9e-29 101.9 1.6 2.9e-29 101.9 1.6 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 LMBR1 PF04791.16 CUU99089.1 - 0.067 12.1 0.7 0.087 11.7 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lipoprotein_Ltp PF07553.11 CUU99090.1 - 0.066 13.5 0.1 0.12 12.6 0.0 1.4 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Copine PF07002.16 CUU99091.1 - 2.2e-76 256.1 0.1 5.6e-47 160.0 0.0 2.1 1 1 1 2 2 2 2 Copine vWA-TerF-like PF10138.9 CUU99091.1 - 3.9e-11 43.4 0.0 1.3e-06 28.7 0.0 2.3 1 1 1 2 2 2 2 vWA found in TerF C terminus GIT_CC PF16559.5 CUU99093.1 - 0.0011 18.8 0.3 0.0032 17.3 0.3 1.8 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 CUU99093.1 - 0.031 14.1 0.3 0.07 13.0 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CUU99093.1 - 0.09 13.4 0.3 0.33 11.6 0.3 1.9 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 CUU99093.1 - 0.097 13.0 0.0 0.38 11.1 0.0 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4407 PF14362.6 CUU99093.1 - 2.1 7.6 6.1 3.9 6.8 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L7Ae PF01248.26 CUU99094.1 - 7.2e-15 54.5 0.4 1.2e-14 53.8 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PqqD PF05402.12 CUU99094.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Septin PF00735.18 CUU99095.1 - 4.5e-103 344.4 0.0 6.6e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CUU99095.1 - 3.2e-05 24.0 0.0 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CUU99095.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 CUU99095.1 - 0.0035 16.9 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Strep_SA_rep PF06696.11 CUU99095.1 - 0.0043 17.0 0.2 0.0094 15.9 0.2 1.6 1 0 0 1 1 1 1 Streptococcal surface antigen repeat AAA_24 PF13479.6 CUU99095.1 - 0.0068 16.2 0.4 0.09 12.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CUU99095.1 - 0.0097 15.3 0.0 0.034 13.5 0.0 1.9 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CUU99095.1 - 0.013 15.4 0.0 0.049 13.5 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CUU99095.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CUU99095.1 - 0.023 15.1 0.1 0.059 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RNase_H2_suC PF08615.11 CUU99096.1 - 1.1e-06 28.9 0.0 0.00011 22.4 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Enterotoxin_b PF01376.18 CUU99096.1 - 0.057 13.6 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain RRM_5 PF13893.6 CUU99096.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CUU99097.1 - 7.3e-51 169.1 20.6 4.1e-11 43.2 0.1 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat mRNA_cap_enzyme PF01331.19 CUU99097.1 - 2.2e-42 145.1 0.0 1.9e-41 142.1 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain ANAPC4_WD40 PF12894.7 CUU99097.1 - 4.4e-26 91.0 0.2 4.6e-08 33.2 0.1 6.2 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain mRNA_cap_C PF03919.15 CUU99097.1 - 9.8e-16 58.3 0.0 2.3e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CUU99097.1 - 8.6e-13 48.2 0.1 1.7e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain eIF2A PF08662.11 CUU99097.1 - 1.7e-10 41.1 0.7 2.4e-05 24.3 0.5 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CUU99097.1 - 4.7e-05 22.9 0.0 1.2 8.4 0.0 4.0 4 1 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CUU99097.1 - 0.00025 20.1 0.8 1.5 7.7 0.4 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase PF00102.27 CUU99097.1 - 0.00049 19.7 0.1 0.00087 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nup160 PF11715.8 CUU99097.1 - 0.0019 16.9 6.7 2.1 6.9 0.2 5.0 4 2 2 6 6 6 1 Nucleoporin Nup120/160 IKI3 PF04762.12 CUU99097.1 - 0.0085 14.1 0.3 0.048 11.7 0.3 2.0 1 1 0 1 1 1 1 IKI3 family PTPlike_phytase PF14566.6 CUU99097.1 - 0.017 15.3 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate LisH PF08513.11 CUU99097.1 - 0.026 14.5 0.5 0.092 12.7 0.5 2.0 1 0 0 1 1 1 0 LisH DNA_ligase_A_M PF01068.21 CUU99097.1 - 0.064 12.9 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 ATP dependent DNA ligase domain Y_phosphatase3 PF13350.6 CUU99097.1 - 0.18 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family EGF PF00008.27 CUU99098.1 - 5.8e-93 304.6 312.0 1.2e-07 31.9 10.1 23.9 22 1 0 22 22 22 21 EGF-like domain hEGF PF12661.7 CUU99098.1 - 1.5e-48 161.8 263.5 1.4e-05 25.5 8.7 25.6 24 3 0 24 24 24 19 Human growth factor-like EGF EGF_2 PF07974.13 CUU99098.1 - 4.5e-24 84.5 378.6 0.0039 17.5 10.1 24.3 24 1 0 24 24 22 18 EGF-like domain Ank_2 PF12796.7 CUU99098.1 - 1.1e-21 77.2 10.5 4.3e-11 43.2 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU99098.1 - 1.6e-21 76.4 0.4 9.8e-05 22.8 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) NOD PF06816.13 CUU99098.1 - 1.4e-17 63.0 0.1 2.9e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 NOTCH protein Ank_5 PF13857.6 CUU99098.1 - 1.5e-16 60.2 3.7 2.5e-05 24.4 0.3 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CUU99098.1 - 1.6e-15 56.8 5.9 0.0034 17.7 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CUU99098.1 - 5.7e-15 53.9 2.3 0.016 15.7 0.1 6.8 6 0 0 6 6 6 3 Ankyrin repeat Notch PF00066.17 CUU99098.1 - 3.6e-13 49.7 25.8 1.8e-10 41.1 8.7 8.7 10 0 0 10 10 3 2 LNR domain EGF_CA PF07645.15 CUU99098.1 - 1.6e-12 47.4 52.5 1.4e-07 31.5 5.9 22.1 11 5 12 23 23 19 8 Calcium-binding EGF domain DUF3454 PF11936.8 CUU99098.1 - 7.2 7.1 12.6 1.2 9.5 4.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) UQ_con PF00179.26 CUU99099.1 - 1.1e-46 158.0 0.0 1.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CUU99099.1 - 0.0092 16.3 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CUU99099.1 - 0.17 11.5 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B COG6 PF06419.11 CUU99100.1 - 5.6e-81 272.6 3.2 7.3e-81 272.2 3.2 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Hpt PF01627.23 CUU99100.1 - 0.063 13.5 0.1 0.24 11.7 0.1 2.1 1 0 0 1 1 1 0 Hpt domain DUF4064 PF13273.6 CUU99101.1 - 1.2e-05 25.5 3.4 0.0018 18.5 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) COPI_assoc PF08507.10 CUU99101.1 - 9.8e-05 22.4 1.6 0.036 14.1 0.1 2.9 3 0 0 3 3 3 1 COPI associated protein DUF202 PF02656.15 CUU99101.1 - 0.00054 20.4 1.5 0.034 14.6 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) GPDPase_memb PF10110.9 CUU99101.1 - 0.00062 18.6 0.5 0.004 16.0 0.1 1.9 2 0 0 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Tetraspanin PF00335.20 CUU99101.1 - 0.00069 19.4 2.1 0.039 13.7 1.7 2.2 2 0 0 2 2 2 1 Tetraspanin family PIG-Y PF15159.6 CUU99101.1 - 0.00099 20.0 0.1 3.2 8.8 0.0 2.9 3 0 0 3 3 3 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TRP PF06011.12 CUU99101.1 - 0.0036 16.1 0.0 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF308 PF03729.13 CUU99101.1 - 0.0073 16.6 12.2 3.2 8.2 1.2 3.1 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) TctB PF07331.11 CUU99101.1 - 0.0078 16.5 0.1 0.32 11.3 0.1 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family DUF423 PF04241.15 CUU99101.1 - 0.0082 16.3 2.7 1.5 9.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF423) DUF3169 PF11368.8 CUU99101.1 - 0.011 15.2 1.9 0.034 13.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2157 PF09925.9 CUU99101.1 - 0.013 15.3 3.0 1.8 8.3 1.6 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Ferric_reduct PF01794.19 CUU99101.1 - 0.017 15.3 0.3 2.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF4834 PF16118.5 CUU99101.1 - 0.017 16.1 1.8 1.4 9.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) O_anti_polymase PF01901.16 CUU99101.1 - 0.02 14.2 1.5 0.5 9.6 0.9 2.0 2 0 0 2 2 2 0 Putative O-antigen polymerase DUF2207 PF09972.9 CUU99101.1 - 0.023 13.5 3.3 0.87 8.3 4.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Amastin PF07344.11 CUU99101.1 - 0.03 14.2 1.2 0.39 10.6 0.5 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein OATP PF03137.20 CUU99101.1 - 0.032 12.5 0.6 0.085 11.1 0.5 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.13 CUU99101.1 - 0.036 14.7 2.7 0.036 14.7 2.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Orai-1 PF07856.12 CUU99101.1 - 0.037 13.7 2.7 0.41 10.3 2.7 2.1 1 1 0 1 1 1 0 Mediator of CRAC channel activity TMEM51 PF15345.6 CUU99101.1 - 0.041 13.7 0.0 0.096 12.5 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 TssO PF17561.2 CUU99101.1 - 0.05 13.7 6.5 1.1 9.3 0.1 2.9 2 1 1 3 3 3 0 Type VI secretion system, TssO LMBR1 PF04791.16 CUU99101.1 - 0.05 12.5 0.8 0.12 11.2 0.3 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein FxsA PF04186.13 CUU99101.1 - 0.051 13.7 0.1 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF4282 PF14110.6 CUU99101.1 - 0.053 14.2 5.2 0.18 12.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF898 PF05987.13 CUU99101.1 - 0.058 12.4 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) TMEM52 PF14979.6 CUU99101.1 - 0.081 12.8 0.6 5.2 7.0 0.5 2.7 2 1 0 2 2 2 0 Transmembrane 52 DUF4231 PF14015.6 CUU99101.1 - 0.082 13.4 0.8 0.23 11.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) EphA2_TM PF14575.6 CUU99101.1 - 0.1 13.5 0.2 55 4.7 0.7 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DHHC PF01529.20 CUU99101.1 - 0.13 12.3 4.6 0.63 10.1 1.2 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase STE2 PF02116.15 CUU99101.1 - 0.3 10.3 8.0 0.23 10.8 0.9 2.1 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR DUF5090 PF17009.5 CUU99101.1 - 0.32 10.9 5.5 0.94 9.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) ATP-synt_8 PF00895.20 CUU99101.1 - 0.34 11.4 7.5 1.3 9.6 0.2 3.0 3 0 0 3 3 2 0 ATP synthase protein 8 DUF1218 PF06749.12 CUU99101.1 - 0.38 11.3 5.5 1.1 9.9 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF3185 PF11381.8 CUU99101.1 - 0.57 10.2 15.4 9.6 6.3 1.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) DUF3899 PF13038.6 CUU99101.1 - 0.63 10.6 0.0 0.63 10.6 0.0 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) DUF2892 PF11127.8 CUU99101.1 - 0.67 10.0 8.3 18 5.5 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) DUF3040 PF11239.8 CUU99101.1 - 0.85 9.9 6.1 51 4.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Sigma_reg_N PF13800.6 CUU99101.1 - 1.1 9.6 6.1 29 5.0 0.3 3.0 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Phage_holin_3_6 PF07332.11 CUU99101.1 - 2 8.5 6.7 7.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III IncE PF17627.2 CUU99101.1 - 6.7 6.7 8.3 70 3.4 6.1 2.8 2 1 0 2 2 2 0 Inclusion membrane protein E TMEM100 PF16311.5 CUU99102.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 DUF1700 PF08006.11 CUU99103.1 - 0.0048 16.5 1.9 0.0066 16.0 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) DUF2207 PF09972.9 CUU99103.1 - 0.0082 15.0 1.0 0.0088 14.9 1.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 CUU99103.1 - 0.0082 15.9 2.3 0.01 15.5 2.3 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 CUU99103.1 - 0.45 10.8 8.9 2 8.8 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3899 PF13038.6 CUU99103.1 - 0.56 10.7 4.0 1.9 9.0 4.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) DUF872 PF05915.12 CUU99103.1 - 1.5 9.0 5.2 5.6 7.2 0.2 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CEBP_ZZ PF16366.5 CUU99104.1 - 0.023 14.9 1.0 0.047 13.9 1.0 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Copine PF07002.16 CUU99105.1 - 2.2e-76 256.1 0.1 5.6e-47 160.0 0.0 2.1 1 1 1 2 2 2 2 Copine vWA-TerF-like PF10138.9 CUU99105.1 - 3.9e-11 43.4 0.0 1.3e-06 28.7 0.0 2.3 1 1 1 2 2 2 2 vWA found in TerF C terminus CNOT1_HEAT PF16418.5 CUU99106.1 - 0.016 15.3 0.2 0.39 10.8 0.0 2.0 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Filament PF00038.21 CUU99107.1 - 1.3e-05 25.0 126.9 0.025 14.2 18.3 6.9 1 1 5 6 6 6 3 Intermediate filament protein Fez1 PF06818.15 CUU99107.1 - 0.0038 17.7 126.6 0.011 16.2 12.8 7.8 1 1 8 9 9 9 5 Fez1 BST2 PF16716.5 CUU99107.1 - 0.01 16.4 6.8 0.01 16.4 6.8 13.1 4 1 9 14 14 14 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 CUU99107.1 - 0.016 15.2 1.1 0.016 15.2 1.1 15.6 6 4 15 21 21 21 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 CUU99107.1 - 0.043 14.2 0.5 0.043 14.2 0.5 12.6 12 3 3 15 15 15 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 CUU99107.1 - 0.12 12.2 9.4 1.5 8.7 0.1 5.2 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 CUU99107.1 - 0.23 10.3 137.0 0.12 11.3 18.7 8.5 3 2 6 9 9 9 0 Spc7 kinetochore protein KASH_CCD PF14662.6 CUU99107.1 - 2.1 8.2 142.6 0.037 13.9 12.2 8.4 3 2 4 7 7 7 0 Coiled-coil region of CCDC155 or KASH SNCAIP_SNCA_bd PF16700.5 CUU99107.1 - 7.5 6.4 21.7 0.068 12.9 1.1 5.1 4 0 0 4 4 4 0 Synphilin-1 alpha-Synuclein-binding domain TPR_MLP1_2 PF07926.12 CUU99107.1 - 8.8 6.4 165.0 0.054 13.5 14.1 11.5 3 2 8 12 12 12 0 TPR/MLP1/MLP2-like protein SH3_10 PF17902.1 CUU99108.1 - 0.086 12.9 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 SH3 domain DnaA_N PF11638.8 CUU99110.1 - 0.019 14.7 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 DnaA N-terminal domain PDDEXK_1 PF12705.7 CUU99110.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.7 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily Methyltrans_SAM PF10672.9 CUU99110.1 - 0.15 11.2 0.0 0.73 8.9 0.0 1.9 1 1 1 2 2 2 0 S-adenosylmethionine-dependent methyltransferase Kunitz_BPTI PF00014.23 CUU99114.1 - 3.8e-152 494.5 127.9 7.3e-20 71.0 3.7 10.8 11 0 0 11 11 11 9 Kunitz/Bovine pancreatic trypsin inhibitor domain NIDO PF06119.14 CUU99114.1 - 2.7e-08 34.7 0.0 1.4e-06 29.2 0.0 2.8 2 0 0 2 2 2 1 Nidogen-like FliMN_C PF01052.20 CUU99114.1 - 0.21 11.6 0.1 37 4.4 0.0 2.5 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term MSP7_C PF12948.7 CUU99114.1 - 0.22 12.2 0.0 42 4.8 0.0 2.3 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain Kelch_5 PF13854.6 CUU99116.1 - 7.5e-06 25.8 0.0 4.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CUU99116.1 - 9.3e-06 25.6 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CUU99116.1 - 0.0082 16.1 0.0 0.72 9.9 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 CUU99116.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_3 PF13415.6 CUU99117.1 - 7.6e-14 51.6 0.6 0.00016 21.9 0.1 3.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CUU99117.1 - 2.2e-12 46.8 1.4 1.6e-06 28.0 0.3 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CUU99117.1 - 7.4e-11 41.8 0.3 0.0047 16.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CUU99117.1 - 1.8e-08 34.3 0.4 0.00022 21.4 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CUU99117.1 - 3.5e-08 32.9 0.5 0.0052 16.4 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CUU99117.1 - 5.3e-06 26.2 1.6 0.00043 20.1 0.1 3.3 3 1 0 3 3 3 1 Kelch motif Ion_trans PF00520.31 CUU99118.1 - 4.1e-06 26.2 0.0 5.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CUU99118.1 - 0.00058 19.8 0.6 0.00082 19.3 0.6 1.2 1 0 0 1 1 1 1 Ion channel DUF4735 PF15882.5 CUU99119.1 - 3e-23 82.7 8.7 4.9e-23 82.0 8.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4735) Tn7_Tnp_TnsA_C PF08721.11 CUU99119.1 - 0.012 16.3 0.2 0.034 14.8 0.2 1.7 1 0 0 1 1 1 0 TnsA endonuclease C terminal ATS3 PF06232.11 CUU99119.1 - 0.031 14.2 0.1 9.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) Laminin_G_2 PF02210.24 CUU99120.1 - 3.2e-72 241.0 8.6 7.9e-23 81.4 0.1 4.5 4 0 0 4 4 4 4 Laminin G domain Laminin_G_1 PF00054.23 CUU99120.1 - 4.7e-51 172.4 1.8 8.8e-21 74.5 0.0 4.9 4 1 0 4 4 4 4 Laminin G domain F5_F8_type_C PF00754.25 CUU99120.1 - 2.5e-25 89.0 1.0 8.2e-25 87.4 0.2 2.3 2 0 0 2 2 2 1 F5/8 type C domain Laminin_G_3 PF13385.6 CUU99120.1 - 5.7e-12 46.0 9.4 0.01 16.0 0.1 5.0 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.27 CUU99120.1 - 3.5e-05 24.0 23.4 0.00042 20.6 6.7 3.6 3 0 0 3 3 3 2 EGF-like domain DUF1804 PF08822.11 CUU99124.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pkinase PF00069.25 CUU99126.1 - 1.2e-81 274.0 0.5 3.4e-44 151.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99126.1 - 5.2e-21 75.1 0.0 1.9e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CUU99126.1 - 0.0012 18.2 0.0 0.21 10.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CUU99126.1 - 0.0082 16.1 0.2 16 5.3 0.4 3.6 2 2 1 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CUU99126.1 - 0.011 14.5 0.1 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CUU99126.1 - 0.034 13.5 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CARD PF00619.21 CUU99127.1 - 2.8e-15 56.1 0.1 5.6e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Caspase recruitment domain NB-ARC PF00931.22 CUU99127.1 - 3.6e-12 46.0 0.0 4.6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain APAF1_C PF17908.1 CUU99127.1 - 1.9e-10 40.9 0.2 1.2e-08 35.0 0.0 2.7 3 0 0 3 3 3 1 APAF-1 helical domain CARD_2 PF16739.5 CUU99127.1 - 1.2e-08 34.8 0.1 2.8e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Caspase recruitment domain AAA_16 PF13191.6 CUU99127.1 - 0.0049 17.3 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CUU99127.1 - 0.13 12.7 0.0 0.58 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1082 PF06449.11 CUU99128.1 - 0.033 14.0 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) RhoGEF PF00621.20 CUU99131.1 - 6.6e-15 55.8 11.3 5.1e-14 52.9 0.4 4.4 4 1 0 4 4 4 2 RhoGEF domain Snapin_Pallidin PF14712.6 CUU99131.1 - 1.3e-09 38.3 0.8 1.3e-09 38.3 0.8 5.1 5 0 0 5 5 5 1 Snapin/Pallidin PH PF00169.29 CUU99131.1 - 4.7e-05 23.9 0.2 0.11 13.1 0.0 3.8 3 0 0 3 3 3 1 PH domain PH_2 PF08458.10 CUU99131.1 - 0.043 14.2 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region IQ_SEC7_PH PF16453.5 CUU99131.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 PH domain RibD_C PF01872.17 CUU99131.1 - 0.16 11.8 0.3 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 RibD C-terminal domain Laminin_G_2 PF02210.24 CUU99132.1 - 5.2e-08 33.5 0.0 7.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CUU99132.1 - 3.7e-06 27.2 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CUU99133.1 - 5.2e-08 33.5 0.0 7.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 CUU99133.1 - 3.7e-06 27.2 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain LIN37 PF15306.6 CUU99134.1 - 0.0058 16.9 0.8 0.011 15.9 0.2 1.7 2 0 0 2 2 2 1 LIN37 TPPII_N PF12583.8 CUU99134.1 - 8.9 6.9 9.4 1.2 9.7 0.5 2.1 1 1 1 2 2 2 0 Tripeptidyl peptidase II N terminal DUF5521 PF17659.1 CUU99138.1 - 0.024 12.5 0.1 0.027 12.4 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RIB43A PF05914.12 CUU99139.1 - 1.2e-36 126.3 5.7 1.3e-36 126.2 5.7 1.0 1 0 0 1 1 1 1 RIB43A Fungal_TACC PF12709.7 CUU99139.1 - 0.04 14.4 8.3 0.067 13.7 8.3 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4670 PF15709.5 CUU99139.1 - 0.93 8.7 16.0 1 8.6 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) YgaB PF14182.6 CUU99139.1 - 6.5 7.2 12.8 2.8 8.4 3.1 2.2 1 1 1 2 2 2 0 YgaB-like protein Innexin PF00876.18 CUU99140.1 - 3.6e-46 158.1 1.8 5e-46 157.6 1.8 1.1 1 0 0 1 1 1 1 Innexin Kelch_1 PF01344.25 CUU99141.1 - 1.7e-60 200.4 15.8 1.6e-14 53.2 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CUU99141.1 - 1.1e-40 136.6 6.9 8.1e-08 32.3 0.0 6.4 2 1 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CUU99141.1 - 6.3e-25 86.2 7.5 1.4e-05 24.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CUU99141.1 - 1.2e-18 66.9 4.3 0.00083 19.6 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CUU99141.1 - 2.3e-17 62.7 1.8 0.006 16.6 0.0 5.6 5 1 1 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 CUU99141.1 - 1.6e-15 57.1 0.8 3.4e-15 56.0 0.8 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CUU99141.1 - 1.3e-13 50.6 4.5 0.0008 19.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif NIBRIN_BRCT_II PF16508.5 CUU99144.1 - 1.5e-09 38.2 0.0 7.4e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein PDZ PF00595.24 CUU99145.1 - 1.5e-56 188.6 4.0 2.8e-14 53.2 0.2 4.9 4 1 0 4 4 4 4 PDZ domain PDZ_6 PF17820.1 CUU99145.1 - 4.1e-29 100.2 6.2 7.9e-08 32.0 0.0 4.4 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CUU99145.1 - 3.7e-16 59.2 1.9 0.00032 21.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-RING_UBOX PF13445.6 CUU99145.1 - 1.6e-06 28.0 9.5 3.9e-06 26.8 9.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CUU99145.1 - 6.7e-06 25.9 6.5 1.8e-05 24.5 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 CUU99145.1 - 2.8e-05 24.7 2.1 9.2e-05 23.1 2.1 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 CUU99145.1 - 3.7e-05 23.5 7.7 9.3e-05 22.2 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CUU99145.1 - 5.1e-05 23.3 6.2 0.00014 22.0 6.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CUU99145.1 - 0.00046 20.1 5.1 0.00046 20.1 5.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CUU99145.1 - 0.00048 19.9 3.7 0.00048 19.9 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CUU99145.1 - 0.00087 19.6 6.0 0.0028 17.9 6.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-TRAF_2 PF15965.5 CUU99145.1 - 0.0012 19.2 5.9 0.0012 19.2 5.9 1.9 1 1 1 2 2 2 1 TRAF-like zinc-finger Sina PF03145.16 CUU99145.1 - 0.058 13.3 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-RING_10 PF16685.5 CUU99145.1 - 0.12 12.5 10.5 0.027 14.6 6.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Maf_N PF08383.11 CUU99145.1 - 1.1 9.1 3.4 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 Maf N-terminal region Glyco_transf_64 PF09258.10 CUU99146.1 - 2.1e-90 302.3 0.2 2.7e-90 301.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CUU99146.1 - 4.3e-05 22.9 0.0 8.1e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Exostosin family Tektin PF03148.14 CUU99146.1 - 0.017 13.9 3.3 0.023 13.4 3.3 1.2 1 0 0 1 1 1 0 Tektin family Lzipper-MIP1 PF14389.6 CUU99146.1 - 0.029 14.7 2.3 0.06 13.7 2.3 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Glyco_tranf_2_3 PF13641.6 CUU99146.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Cortex-I_coil PF09304.10 CUU99146.1 - 0.092 13.0 2.0 0.21 11.8 2.0 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil ADIP PF11559.8 CUU99146.1 - 0.11 12.6 1.3 0.18 11.9 1.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DegS PF05384.11 CUU99146.1 - 0.13 11.8 1.3 0.23 11.0 1.3 1.3 1 0 0 1 1 1 0 Sensor protein DegS Syntaxin-6_N PF09177.11 CUU99146.1 - 0.42 11.2 1.6 0.93 10.1 1.6 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TFIIF_alpha PF05793.12 CUU99147.1 - 1.1e-38 133.2 24.0 1.1e-38 133.2 24.0 3.8 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIF_alpha PF05793.12 CUU99148.1 - 1.1e-38 133.2 24.0 1.1e-38 133.2 24.0 3.8 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIF_alpha PF05793.12 CUU99150.1 - 1.5e-16 60.1 18.3 1.8e-16 59.8 18.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3123 PF11321.8 CUU99150.1 - 0.023 15.4 3.2 0.041 14.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) PCM1_C PF15717.5 CUU99150.1 - 0.11 11.2 13.8 0.13 10.9 13.8 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PI3K_1B_p101 PF10486.9 CUU99150.1 - 0.28 8.9 11.3 0.31 8.8 11.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 CUU99150.1 - 1.8 5.5 13.5 2 5.4 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CUU99150.1 - 2.5 6.5 11.3 2.8 6.4 11.3 1.1 1 0 0 1 1 1 0 Macoilin family Pes-10 PF07149.11 CUU99150.1 - 6.1 5.8 8.0 63 2.4 0.0 2.1 2 0 0 2 2 2 0 Pes-10 COX6B PF02297.17 CUU99151.1 - 2.4e-13 50.1 0.7 2.9e-13 49.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb FXa_inhibition PF14670.6 CUU99153.1 - 0.0042 17.3 5.3 0.0097 16.2 5.3 1.6 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site SUKH-4 PF14435.6 CUU99153.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein DUF1367 PF07105.11 CUU99155.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) LINES_N PF14694.6 CUU99156.1 - 1.5e-05 24.7 1.0 2.4e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 Lines N-terminus Rhodanese PF00581.20 CUU99158.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Longin PF13774.6 CUU99159.1 - 1.4e-22 79.5 0.0 2.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CUU99159.1 - 3.6e-15 55.5 0.4 7.6e-15 54.5 0.1 1.7 2 0 0 2 2 2 1 Synaptobrevin YgaB PF14182.6 CUU99159.1 - 0.023 15.1 0.9 0.057 13.8 0.3 1.9 2 0 0 2 2 2 0 YgaB-like protein Sec20 PF03908.13 CUU99159.1 - 0.04 13.8 0.7 0.073 13.0 0.1 1.8 2 0 0 2 2 2 0 Sec20 GP41 PF00517.17 CUU99159.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Peptidase_C2 PF00648.21 CUU99160.1 - 8.3e-24 84.1 0.0 9.7e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 CUU99161.1 - 1.7e-58 198.0 0.0 2.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Sas6_CC PF18594.1 CUU99162.1 - 0.033 14.0 3.3 15 5.5 0.2 4.2 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain DUF1088 PF06469.11 CUU99163.1 - 5.4e-08 32.7 0.0 5.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) BACK PF07707.15 CUU99166.1 - 3.7e-09 36.6 0.1 1.1e-05 25.4 0.0 2.9 1 1 2 3 3 3 2 BTB And C-terminal Kelch Kelch_1 PF01344.25 CUU99166.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 CUU99166.1 - 1.6e-05 25.0 0.0 5.3e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Kelch motif RT_RNaseH_2 PF17919.1 CUU99167.1 - 3e-05 24.0 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CUU99167.1 - 0.033 14.5 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF4506 PF14958.6 CUU99170.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Herpes_UL7 PF01677.16 CUU99170.1 - 0.15 11.7 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL7 like RAM PF15320.6 CUU99171.1 - 1.9e-11 44.4 4.7 2.6e-11 44.0 4.7 1.2 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein RasGEF PF00617.19 CUU99172.1 - 2e-23 83.5 0.0 4.9e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CUU99172.1 - 8.1e-10 38.9 1.4 2.1e-09 37.5 1.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Tubulin PF00091.25 CUU99173.1 - 2.2e-70 236.9 0.0 3.9e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CUU99173.1 - 1.4e-42 144.8 0.1 2.3e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CUU99173.1 - 2.6e-05 24.5 0.0 7.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CUU99173.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CUU99173.1 - 0.058 12.6 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Tubulin like zf-C2H2_4 PF13894.6 CUU99175.1 - 6.7e-09 35.8 14.8 0.0029 18.3 0.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CUU99175.1 - 9.2e-09 35.3 19.7 0.00027 21.2 2.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CUU99175.1 - 0.00085 19.6 8.9 0.014 15.7 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CUU99175.1 - 0.0074 16.3 13.7 0.33 11.0 2.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CUU99175.1 - 0.02 15.2 16.6 0.082 13.2 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CUU99175.1 - 0.026 15.2 5.7 1.6 9.4 1.4 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-trcl PF13451.6 CUU99175.1 - 0.14 12.1 6.0 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_2 PF12756.7 CUU99175.1 - 0.16 12.4 12.8 0.066 13.6 4.9 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 CUU99175.1 - 0.18 12.1 0.5 0.59 10.5 0.4 1.9 2 0 0 2 2 2 0 BolA-like protein zf_ZIC PF18366.1 CUU99175.1 - 0.24 11.5 4.3 0.87 9.7 0.2 2.6 2 0 0 2 2 2 0 Zic proteins zinc finger domain LIM PF00412.22 CUU99175.1 - 0.64 10.3 12.0 1.5 9.1 1.8 2.6 1 1 1 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.10 CUU99175.1 - 0.94 9.6 7.7 13 6.0 2.1 3.0 2 1 0 2 2 2 0 Zinc ribbon domain Actin_micro PF17003.5 CUU99175.1 - 1.8 7.7 6.1 4.1 6.5 5.9 1.6 1 1 0 1 1 1 0 Putative actin-like family MOZART2 PF12926.7 CUU99177.1 - 1.1e-08 34.5 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated 7tm_1 PF00001.21 CUU99178.1 - 8.2e-07 28.6 8.2 8.2e-07 28.6 8.2 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CUU99178.1 - 0.052 12.8 21.1 6.2 6.0 14.1 3.3 2 2 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw MDM1 PF15501.6 CUU99179.1 - 0.45 9.6 28.9 1.3e+03 -1.8 28.9 3.1 1 1 0 1 1 1 0 Nuclear protein MDM1 Ras PF00071.22 CUU99180.1 - 3.2e-09 36.6 0.0 4.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Cnd3 PF12719.7 CUU99180.1 - 0.011 15.0 0.0 1.2 8.3 0.0 2.1 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain KcnmB2_inactiv PF09303.10 CUU99180.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.6 3 0 0 3 3 3 0 KCNMB2, ball and chain domain FRG2 PF15315.6 CUU99180.1 - 4.7 7.4 15.8 7.1 6.8 2.7 2.3 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 CENP-T_C PF15511.6 CUU99181.1 - 1.8e-08 34.5 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CUU99181.1 - 2.5e-05 24.4 0.2 3.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CUU99181.1 - 4.6e-05 23.7 0.1 6.1e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CUU99181.1 - 0.00017 21.9 0.3 0.00019 21.8 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CUU99181.1 - 0.00028 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CUU99181.1 - 0.0059 16.7 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CUU99181.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CUU99181.1 - 0.21 11.4 0.1 0.25 11.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone_H2A_C PF16211.5 CUU99182.1 - 1.6e-21 75.7 1.3 2.6e-21 75.0 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CUU99182.1 - 3.2e-15 56.6 0.0 4.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CUU99182.1 - 1.9e-05 24.8 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CUU99183.1 - 9.5e-22 77.8 1.9 1.2e-21 77.4 1.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CUU99183.1 - 6.8e-06 26.3 0.1 1.8e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CUU99183.1 - 0.00083 19.8 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CUU99183.1 - 0.0018 18.4 0.2 0.0021 18.1 0.2 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 CUU99183.1 - 0.0031 17.5 0.5 0.0034 17.3 0.5 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3915 PF13054.6 CUU99183.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RecG_N PF17190.4 CUU99184.1 - 0.042 14.6 0.6 0.15 12.8 0.2 2.0 2 0 0 2 2 2 0 RecG N-terminal helical domain CoaE PF01121.20 CUU99185.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase SMK-1 PF04802.15 CUU99186.1 - 2.1e-120 399.6 20.4 3.6e-60 203.1 1.8 4.4 4 0 0 4 4 4 2 Component of IIS longevity pathway SMK-1 Ten1 PF12658.7 CUU99186.1 - 3.4e-05 23.8 0.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 2 Telomere capping, CST complex subunit zf-DBF PF07535.12 CUU99186.1 - 0.0016 18.5 0.7 8.7 6.5 0.1 4.0 4 0 0 4 4 4 2 DBF zinc finger MMS19_C PF12460.8 CUU99186.1 - 0.0057 15.8 3.1 3 6.9 0.0 3.8 6 0 0 6 6 6 2 RNAPII transcription regulator C-terminal Rep_fac-A_3 PF08661.11 CUU99186.1 - 0.0059 16.9 4.0 2.5 8.5 0.3 2.8 2 0 0 2 2 2 2 Replication factor A protein 3 TubC_N PF18563.1 CUU99186.1 - 0.0067 16.4 0.8 5.6 7.0 0.1 2.7 2 0 0 2 2 2 2 TubC N-terminal docking domain DUF1955 PF09205.10 CUU99186.1 - 0.027 14.2 1.0 11 5.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Retro_M PF02813.14 CUU99186.1 - 0.047 14.1 0.0 2.2 8.8 0.0 3.0 2 0 0 2 2 2 0 Retroviral M domain RNR_Alpha PF17975.1 CUU99186.1 - 0.1 13.1 0.1 35 5.0 0.0 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain LeuA_dimer PF08502.10 CUU99186.1 - 0.19 11.6 0.0 21 5.0 0.0 2.4 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain DEAD PF00270.29 CUU99187.1 - 4.6e-40 137.2 0.0 7.8e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CUU99187.1 - 7.5e-27 93.9 0.2 4.5e-26 91.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SwrA PF17423.2 CUU99187.1 - 0.13 12.2 0.6 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 Swarming motility protein Ctr PF04145.15 CUU99188.1 - 4.7e-35 121.4 1.1 5.6e-35 121.1 1.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SR-25 PF10500.9 CUU99189.1 - 7.4 6.1 24.7 0.56 9.8 19.1 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Pacs-1 PF10254.9 CUU99190.1 - 4.4e-14 52.3 0.9 9.7e-10 38.0 0.0 2.2 2 0 0 2 2 2 2 PACS-1 cytosolic sorting protein Hydrolase_6 PF13344.6 CUU99191.1 - 5e-16 58.7 0.0 1.1e-15 57.6 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SAPS PF04499.15 CUU99192.1 - 0.038 12.8 12.5 0.038 12.8 12.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 CUU99192.1 - 0.099 10.8 43.6 0.13 10.5 43.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CUU99192.1 - 0.14 11.5 47.4 0.19 11.1 47.4 1.2 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 CUU99192.1 - 0.26 11.3 1.0 0.41 10.7 1.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CUU99192.1 - 0.8 8.4 15.6 1.3 7.8 15.6 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CUU99192.1 - 1.5 8.0 15.4 2.3 7.3 15.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 CUU99192.1 - 1.7 6.7 8.3 1.5 6.8 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 CUU99192.1 - 2.3 6.4 36.9 3.6 5.8 36.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CUU99192.1 - 2.8 6.3 43.6 4.3 5.7 43.6 1.2 1 0 0 1 1 1 0 Mpp10 protein SLC12 PF03522.15 CUU99192.1 - 4.4 6.2 11.8 5.8 5.8 11.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CUU99192.1 - 9.3 6.0 25.6 15 5.3 25.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpb8 PF03870.15 CUU99193.1 - 2.5e-49 167.1 0.5 2.8e-49 166.9 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CUU99193.1 - 2.4e-05 24.4 0.4 0.0022 18.1 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Helicase_C PF00271.31 CUU99196.1 - 1.5e-20 73.6 0.0 4.5e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CUU99196.1 - 1e-11 44.9 0.2 2.7e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) dUTPase PF00692.19 CUU99197.1 - 4.7e-35 120.1 0.0 5.7e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase TIMP PF00965.17 CUU99198.1 - 3.2e-06 27.1 0.0 9.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase Cyclin_N PF00134.23 CUU99200.1 - 2.8e-09 36.8 0.5 4.4e-09 36.2 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CUU99200.1 - 2.1e-07 31.4 0.4 2.1e-07 31.4 0.4 2.4 3 0 0 3 3 3 1 Cyclin DUF2282 PF10048.9 CUU99200.1 - 0.27 11.3 5.6 7.7 6.6 0.5 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2282) DGF-1_C PF11040.8 CUU99202.1 - 0.061 13.3 1.9 0.24 11.4 1.9 2.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Na_Ca_ex PF01699.24 CUU99203.1 - 3.9e-22 78.8 19.9 5.3e-22 78.4 19.9 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DDHD PF02862.17 CUU99205.1 - 2.4e-41 142.4 0.0 4.6e-41 141.4 0.0 1.5 1 1 0 1 1 1 1 DDHD domain Cys_rich_FGFR PF00839.17 CUU99205.1 - 0.33 11.1 2.1 2.9 8.1 0.5 2.4 2 0 0 2 2 2 0 Cysteine rich repeat Ig_3 PF13927.6 CUU99206.1 - 7.3e-06 26.5 0.2 0.089 13.4 0.0 2.6 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CUU99206.1 - 0.00018 21.5 0.0 0.056 13.5 0.0 2.7 2 1 0 2 2 2 2 CD80-like C2-set immunoglobulin domain I-set PF07679.16 CUU99206.1 - 0.004 17.2 0.0 0.056 13.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.25 CUU99206.1 - 0.0074 16.4 0.1 0.25 11.5 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain zf-HC5HC2H PF13771.6 CUU99209.1 - 6.9e-15 55.1 2.6 2.4e-14 53.4 2.6 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CUU99209.1 - 7e-06 26.2 3.9 7e-06 26.2 3.9 2.1 1 1 1 2 2 2 1 PHD-zinc-finger like domain NADH-G_4Fe-4S_3 PF10588.9 CUU99209.1 - 1.6 8.3 5.4 0.5 9.9 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region p53-inducible11 PF14936.6 CUU99210.1 - 4.7e-08 33.3 0.5 4.7e-08 33.3 0.5 2.1 1 1 1 2 2 2 1 Tumour protein p53-inducible protein 11 NdhL PF10716.9 CUU99210.1 - 0.049 13.6 3.3 0.12 12.3 3.3 1.7 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF4181 PF13789.6 CUU99210.1 - 0.41 10.9 7.7 3.5 8.0 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) DUF936 PF06075.12 CUU99216.1 - 2.7 6.8 42.4 3.3 6.5 42.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Asp-B-Hydro_N PF05279.11 CUU99216.1 - 3.6 7.6 12.6 4.3 7.3 12.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Snf7 PF03357.21 CUU99220.1 - 2.7e-26 92.2 9.8 4.5e-26 91.5 9.8 1.4 1 0 0 1 1 1 1 Snf7 7tm_6 PF02949.20 CUU99220.1 - 0.18 10.9 0.1 8.5 5.4 0.0 2.0 2 0 0 2 2 2 0 7tm Odorant receptor SPACA9 PF15120.6 CUU99220.1 - 0.72 9.6 4.6 1.3 8.8 4.6 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF2203 PF09969.9 CUU99220.1 - 6 7.6 6.9 22 5.8 2.6 2.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SIX1_SD PF16878.5 CUU99223.1 - 2e-40 137.8 2.2 2.9e-40 137.2 0.5 1.9 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CUU99223.1 - 3.6e-12 45.9 1.7 9.6e-12 44.6 0.4 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CUU99223.1 - 2.7e-09 36.8 0.5 2.7e-09 36.8 0.5 2.5 3 0 0 3 3 3 1 Homeobox KN domain DUF2353 PF09789.9 CUU99225.1 - 1.4e-09 37.7 13.0 1.6e-08 34.3 7.0 2.0 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) SOGA PF11365.8 CUU99225.1 - 0.048 14.8 0.1 0.048 14.8 0.1 2.5 2 1 0 2 2 2 0 Protein SOGA Peptidase_M16 PF00675.20 CUU99225.1 - 0.094 12.7 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) GAS PF13851.6 CUU99225.1 - 0.12 11.8 13.7 0.82 9.0 0.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 CUU99225.1 - 0.13 10.8 5.3 0.13 10.8 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4pol PF14260.6 CUU99225.1 - 0.39 11.2 6.6 0.14 12.6 3.6 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Cep57_CLD_2 PF14197.6 CUU99225.1 - 1 9.5 18.0 17 5.6 12.8 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 CUU99225.1 - 1.1 9.0 11.6 1.3 8.8 0.6 3.1 2 1 1 3 3 3 0 Septum formation initiator KIAA1430 PF13879.6 CUU99225.1 - 1.3 9.8 13.0 0.35 11.7 3.4 2.2 1 1 1 2 2 2 0 KIAA1430 homologue Mto2_bdg PF12808.7 CUU99225.1 - 1.4 9.3 14.0 19 5.6 0.0 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Seryl_tRNA_N PF02403.22 CUU99225.1 - 2.2 8.6 9.4 3.8 7.8 4.0 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain JIP_LZII PF16471.5 CUU99225.1 - 2.3 8.5 12.4 0.97 9.7 2.3 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II PRKG1_interact PF15898.5 CUU99225.1 - 4.9 8.1 14.8 3.1 8.8 9.9 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Fungal_TACC PF12709.7 CUU99225.1 - 5.4 7.5 11.7 1.6 9.3 3.9 3.0 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins C1q PF00386.21 CUU99231.1 - 1.5e-14 54.3 0.2 1.2e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 C1q domain DUF2730 PF10805.8 CUU99231.1 - 3e-05 24.0 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2730) Glyco_hydro_45 PF02015.16 CUU99231.1 - 0.022 14.7 0.6 3.1 7.7 0.1 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 45 TyeA PF09059.10 CUU99231.1 - 0.023 14.8 0.2 7.5 6.7 0.0 2.2 2 0 0 2 2 2 0 TyeA Flavodoxin_1 PF00258.25 CUU99231.1 - 0.038 14.2 0.0 7 6.9 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin PCNP PF15473.6 CUU99231.1 - 0.05 14.3 0.0 15 6.3 0.0 2.1 2 0 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family RFX1_trans_act PF04589.13 CUU99231.1 - 0.05 13.8 1.5 2.8 8.1 0.1 2.2 2 0 0 2 2 2 0 RFX1 transcription activation region RbcS PF12338.8 CUU99231.1 - 0.086 13.0 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF1330 PF07045.11 CUU99236.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) PT PF04886.12 CUU99239.1 - 0.093 12.3 10.4 0.15 11.6 10.4 1.2 1 0 0 1 1 1 0 PT repeat Surp PF01805.20 CUU99242.1 - 8.5e-19 67.3 0.3 1.5e-18 66.5 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CUU99242.1 - 9.7e-15 54.2 0.0 3e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.12 CUU99242.1 - 2.2e-12 46.9 5.9 7.4e-12 45.2 5.9 2.0 1 0 0 1 1 1 1 cwf21 domain CTD_bind PF04818.13 CUU99242.1 - 4.8e-05 24.1 0.1 0.00048 20.9 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Chlam_OMP6 PF03504.13 CUU99242.1 - 0.0074 16.6 0.1 0.046 14.0 0.0 2.4 2 0 0 2 2 2 1 Chlamydia cysteine-rich outer membrane protein 6 RRM_7 PF16367.5 CUU99242.1 - 0.0089 16.1 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif Kinesin PF00225.23 CUU99244.1 - 4.4e-86 288.8 5.8 1e-85 287.6 0.3 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CUU99244.1 - 1.5e-15 57.4 0.3 2.8e-14 53.3 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding FDX-ACB PF03147.14 CUU99244.1 - 0.075 13.4 0.0 0.31 11.5 0.0 2.0 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain Mon1 PF03164.14 CUU99245.1 - 0.12 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 LIM PF00412.22 CUU99246.1 - 1.8e-09 37.7 1.0 2.6e-09 37.2 1.0 1.2 1 0 0 1 1 1 1 LIM domain PALP PF00291.25 CUU99247.1 - 3.6e-45 154.6 0.2 5.5e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RRM_1 PF00076.22 CUU99247.1 - 6e-18 64.4 0.0 7.7e-17 60.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GKAP PF03359.13 CUU99248.1 - 2.8e-06 27.2 0.1 4.4e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein BolA PF01722.18 CUU99249.1 - 5.1e-25 87.5 1.0 7.2e-25 87.1 1.0 1.2 1 0 0 1 1 1 1 BolA-like protein Mcl1_mid PF12341.8 CUU99250.1 - 2.6e-71 240.4 0.0 3.6e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CUU99250.1 - 7.3e-12 45.6 1.5 0.00018 22.2 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU99250.1 - 0.0024 18.1 0.0 0.039 14.3 0.0 2.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 CUU99250.1 - 6.6 6.0 22.5 2.1 7.6 6.7 2.2 2 0 0 2 2 2 0 BUD22 RRM_1 PF00076.22 CUU99251.1 - 4e-13 49.0 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CUU99251.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif WRW PF10206.9 CUU99252.1 - 1.2e-35 121.9 4.0 2e-35 121.3 4.0 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Actin PF00022.19 CUU99253.1 - 7.6e-58 196.0 0.0 4.5e-41 140.8 0.0 3.0 1 1 2 3 3 3 3 Actin UPF0160 PF03690.13 CUU99255.1 - 7.2e-67 226.3 0.0 1.4e-58 199.0 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0160) Pkinase_Tyr PF07714.17 CUU99259.1 - 1e-40 139.7 0.0 1.1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU99259.1 - 9.3e-20 71.1 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 CUU99262.1 - 1.4e-28 96.5 14.9 0.00043 20.1 0.0 9.0 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 CUU99262.1 - 5.3e-12 45.8 10.4 0.079 13.4 0.1 7.0 3 2 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CUU99262.1 - 8.3e-12 43.9 2.0 8.8 7.3 0.0 9.0 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.6 CUU99262.1 - 1.2e-08 34.6 8.3 0.37 10.6 0.1 7.1 5 2 1 6 6 6 4 Leucine rich repeat Ribosomal_S21e PF01249.18 CUU99264.1 - 8.3e-33 112.4 0.0 9.1e-33 112.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MSP PF01716.18 CUU99264.1 - 0.13 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide TetR_C_36 PF18598.1 CUU99265.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ELMO_CED12 PF04727.13 CUU99266.1 - 1.2e-14 54.9 0.0 2.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 CUU99266.1 - 0.0006 20.4 0.6 0.0017 18.9 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Cation_ATPase_N PF00690.26 CUU99268.1 - 9.6e-18 63.6 0.0 1.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 CUU99269.1 - 1.5e-48 164.9 3.3 5.3e-48 163.1 1.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CUU99269.1 - 2.3e-27 95.7 1.4 5.8e-27 94.4 1.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CUU99269.1 - 3.2e-15 57.0 0.0 1e-11 45.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CUU99269.1 - 4.3e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CUU99269.1 - 0.0034 17.1 1.0 0.0054 16.5 1.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 CUU99269.1 - 4 7.7 5.6 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Enkurin PF13864.6 CUU99270.1 - 4.5e-23 81.5 6.6 4.5e-23 81.5 6.6 1.4 2 0 0 2 2 2 1 Calmodulin-binding Virul_Fac PF10139.9 CUU99270.1 - 0.0032 15.8 0.1 0.0041 15.4 0.1 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor ZIP4_domain PF18292.1 CUU99270.1 - 0.18 11.7 3.3 0.21 11.5 1.8 1.7 2 1 0 2 2 2 0 Zinc transporter ZIP4 domain Ribosomal_L7Ae PF01248.26 CUU99273.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ABC_tran PF00005.27 CUU99275.1 - 4.6e-20 72.5 0.0 9.9e-20 71.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CUU99275.1 - 0.00033 20.6 0.1 0.00043 20.2 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CUU99275.1 - 0.00051 20.1 0.1 0.00072 19.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 CUU99275.1 - 0.00095 18.7 0.2 0.028 13.9 0.1 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 CUU99275.1 - 0.0022 18.1 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 CUU99275.1 - 0.0065 16.9 0.0 0.0087 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CUU99275.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CUU99275.1 - 0.016 15.1 0.3 0.04 13.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 CUU99275.1 - 0.029 14.0 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CUU99275.1 - 0.038 14.3 0.1 0.055 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CUU99275.1 - 0.038 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CUU99275.1 - 0.049 12.4 0.0 6 5.5 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FeoB_N PF02421.18 CUU99275.1 - 0.049 13.2 0.2 0.068 12.7 0.2 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 CUU99275.1 - 0.052 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CUU99275.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CUU99275.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 CUU99275.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain dNK PF01712.19 CUU99275.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_15 PF13175.6 CUU99275.1 - 0.25 11.0 0.1 0.31 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain SBF PF01758.16 CUU99276.1 - 1.5e-34 119.4 10.2 1.5e-34 119.4 10.2 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 CUU99276.1 - 5.4e-11 42.4 8.9 1.3e-10 41.1 8.9 1.5 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Histone PF00125.24 CUU99277.1 - 8.2e-22 78.0 4.0 1e-21 77.6 4.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CUU99277.1 - 1.7e-05 25.0 1.2 2.9e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CUU99277.1 - 0.0011 19.5 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CUU99277.1 - 0.0021 18.1 0.4 0.0026 17.8 0.4 1.2 1 0 0 1 1 1 1 YscO-like protein CNDH2_C PF16858.5 CUU99277.1 - 0.0053 16.7 0.3 0.006 16.5 0.3 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Microcephalin PF12258.8 CUU99277.1 - 0.072 12.3 2.3 0.1 11.9 2.3 1.2 1 0 0 1 1 1 0 Microcephalin protein YvfG PF09628.10 CUU99281.1 - 0.19 12.1 0.1 0.31 11.4 0.1 1.3 1 0 0 1 1 1 0 YvfG protein Cnn_1N PF07989.11 CUU99283.1 - 0.00022 21.3 0.4 0.00026 21.1 0.4 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 CUU99283.1 - 0.00069 19.7 2.1 0.0009 19.3 2.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor TMF_DNA_bd PF12329.8 CUU99283.1 - 0.0053 16.7 0.8 0.0056 16.7 0.8 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 CUU99283.1 - 0.022 14.8 0.3 0.036 14.1 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 CUU99283.1 - 0.025 14.8 0.2 0.028 14.6 0.2 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 CUU99283.1 - 0.027 14.2 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Septum formation initiator HSBP1 PF06825.12 CUU99283.1 - 0.036 13.9 0.2 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF4665 PF15679.5 CUU99283.1 - 0.068 13.8 0.4 0.071 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) XhlA PF10779.9 CUU99283.1 - 0.083 13.1 0.8 0.12 12.6 0.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA zf-MYND PF01753.18 CUU99285.1 - 7.1e-07 29.2 22.2 1.6e-06 28.1 18.7 2.3 2 0 0 2 2 2 1 MYND finger PDCD2_C PF04194.13 CUU99285.1 - 0.00015 21.9 4.4 0.0066 16.5 0.5 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Tox-REase-2 PF15646.6 CUU99285.1 - 0.26 11.5 0.2 0.37 11.0 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 zf-ANAPC11 PF12861.7 CUU99285.1 - 0.35 10.9 10.9 0.08 13.0 7.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Thioredoxin PF00085.20 CUU99287.1 - 3.6e-27 94.4 0.5 4.7e-27 94.0 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CUU99287.1 - 1.4e-05 25.5 0.2 5.7e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CUU99287.1 - 1.8e-05 25.0 0.1 0.0013 19.1 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CUU99287.1 - 6.8e-05 22.7 0.2 8.7e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CUU99287.1 - 0.00014 21.8 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 CUU99287.1 - 0.0016 18.4 0.3 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin domain Redoxin PF08534.10 CUU99287.1 - 0.0026 17.5 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 CUU99287.1 - 0.0034 16.8 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CUU99287.1 - 0.0057 16.5 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 CUU99287.1 - 0.0075 16.0 0.1 0.0094 15.7 0.1 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 CUU99287.1 - 0.011 15.9 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 CUU99287.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 CUU99287.1 - 0.042 14.3 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CUU99287.1 - 0.073 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin Sep15_SelM PF08806.11 CUU99287.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sep15/SelM redox domain Thioredoxin PF00085.20 CUU99288.1 - 3.3e-27 94.5 0.3 3.6e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CUU99288.1 - 7e-06 26.5 0.3 2.7e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CUU99288.1 - 9.4e-06 25.9 0.1 0.00022 21.5 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CUU99288.1 - 0.00031 20.5 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CUU99288.1 - 0.0005 20.0 0.1 0.00062 19.7 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 CUU99288.1 - 0.0013 18.8 0.2 0.0024 17.9 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 CUU99288.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 CUU99288.1 - 0.0041 16.8 0.1 0.0063 16.2 0.1 1.3 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 CUU99288.1 - 0.0044 16.9 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CUU99288.1 - 0.0067 16.6 0.1 0.012 15.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 CUU99288.1 - 0.0077 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 CUU99288.1 - 0.0087 15.8 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF836 PF05768.14 CUU99288.1 - 0.029 14.8 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Sep15_SelM PF08806.11 CUU99288.1 - 0.051 13.7 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Glutaredoxin PF00462.24 CUU99288.1 - 0.053 13.7 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Pkinase_Tyr PF07714.17 CUU99290.1 - 2.1e-23 82.9 0.1 1.9e-12 47.0 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CUU99290.1 - 9.1e-16 58.0 0.0 3.9e-07 29.7 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain PBP_like_2 PF12849.7 CUU99290.1 - 1.9e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain Pkinase PF00069.25 CUU99292.1 - 9.4e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99292.1 - 0.002 17.5 0.0 0.0053 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Transposase_1 PF01359.18 CUU99295.1 - 6.6e-13 48.3 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 CUU99296.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Transposase MAGI_u1 PF16663.5 CUU99300.1 - 0.21 11.7 1.4 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI MAS20 PF02064.15 CUU99302.1 - 0.031 14.4 0.7 0.031 14.4 0.7 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor DUF3391 PF11871.8 CUU99302.1 - 0.94 10.0 5.6 0.95 10.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) HEAT_2 PF13646.6 CUU99304.1 - 0.001 19.4 0.6 0.061 13.7 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CUU99304.1 - 0.0039 17.7 5.1 9 6.9 0.4 4.8 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 CUU99304.1 - 0.34 11.3 15.9 1 9.8 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Dus PF01207.17 CUU99305.1 - 1.7e-72 244.2 0.0 2e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 CUU99305.1 - 6e-05 22.9 3.0 0.00078 19.3 0.2 2.2 1 1 1 2 2 2 1 SOR/SNZ family DHO_dh PF01180.21 CUU99305.1 - 6.8e-05 22.2 0.0 0.00046 19.5 0.0 1.9 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NMO PF03060.15 CUU99305.1 - 0.00019 20.9 0.4 0.00047 19.6 0.3 1.5 1 1 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 CUU99305.1 - 0.00032 19.8 0.0 0.00043 19.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase G3P_antiterm PF04309.12 CUU99305.1 - 0.0027 17.2 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 CUU99305.1 - 0.0039 16.5 0.2 0.0069 15.7 0.2 1.3 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG Oxidored_FMN PF00724.20 CUU99305.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 CUU99305.1 - 0.017 14.6 0.1 0.037 13.5 0.1 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 CUU99305.1 - 0.035 13.1 0.4 0.057 12.4 0.4 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 CUU99305.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase IGPS PF00218.21 CUU99305.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase BtpA PF03437.15 CUU99305.1 - 0.11 11.9 0.2 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 BtpA family Recep_L_domain PF01030.24 CUU99306.1 - 1.9e-15 57.0 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Receptor L domain EST1_DNA_bind PF10373.9 CUU99307.1 - 0.032 13.7 0.0 0.033 13.7 0.0 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain 7tm_1 PF00001.21 CUU99308.1 - 0.05 12.9 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) OapA_N PF08525.11 CUU99308.1 - 0.15 12.0 2.1 0.26 11.3 2.1 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif ubiquitin PF00240.23 CUU99310.1 - 7.8e-11 41.6 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.16 CUU99310.1 - 1.1e-09 38.3 10.1 2.6e-09 37.1 10.1 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger Ribosomal_L32e PF01655.18 CUU99310.1 - 0.041 14.3 1.8 4.3 7.8 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein L32 Nucleoside_tran PF01733.18 CUU99312.1 - 2.5e-29 102.7 6.6 1.1e-18 67.7 1.0 2.0 1 1 1 2 2 2 2 Nucleoside transporter S_2TMBeta PF18153.1 CUU99312.1 - 1.1 9.0 5.1 1.7 8.4 5.1 1.2 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Ribosomal_S27e PF01667.17 CUU99313.1 - 4.8e-24 83.8 0.5 9.6e-24 82.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 HORMA PF02301.18 CUU99313.1 - 2.2e-06 27.4 0.0 9.8e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 HORMA domain zf-LSD1 PF06943.12 CUU99313.1 - 0.53 10.2 4.6 0.57 10.1 2.2 2.1 2 0 0 2 2 2 0 LSD1 zinc finger PGI PF00342.19 CUU99314.1 - 8.8e-225 746.9 3.9 5.3e-223 741.0 3.9 2.0 1 1 0 1 1 1 1 Phosphoglucose isomerase rve PF00665.26 CUU99314.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain WD40 PF00400.32 CUU99315.1 - 9.6e-26 89.6 20.3 7.1e-06 26.7 0.0 8.9 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU99315.1 - 3.2e-10 40.2 0.1 0.43 10.9 0.0 6.8 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CUU99315.1 - 8.4e-06 25.3 0.1 0.017 14.4 0.0 3.1 2 1 0 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 CUU99315.1 - 0.0041 15.9 0.2 3.2 6.4 0.0 3.6 3 1 0 4 4 4 1 Nup133 N terminal like YmzC PF14157.6 CUU99315.1 - 0.062 13.4 0.0 4 7.6 0.0 2.6 2 0 0 2 2 2 0 YmzC-like protein PQQ_2 PF13360.6 CUU99315.1 - 0.064 12.8 0.1 29 4.1 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain Ge1_WD40 PF16529.5 CUU99315.1 - 0.11 11.4 0.3 4.5 6.1 0.0 3.6 4 1 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_2 PF00152.20 CUU99317.1 - 5.1e-75 252.4 0.0 7.2e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CUU99317.1 - 1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CUU99317.1 - 1.7e-09 37.5 0.0 0.00039 20.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) T4_neck-protein PF11649.8 CUU99317.1 - 0.14 11.5 0.1 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Virus neck protein LRR_4 PF12799.7 CUU99318.1 - 8e-47 156.4 100.1 4.8e-06 26.8 1.2 14.8 8 5 4 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CUU99318.1 - 2.3e-33 113.7 95.5 3.3e-10 39.6 2.7 11.6 6 3 5 12 12 12 11 Leucine rich repeat LRR_9 PF14580.6 CUU99318.1 - 6.4e-32 110.4 37.1 6.7e-10 38.7 0.5 7.2 3 2 3 7 7 7 6 Leucine-rich repeat RNase_H PF00075.24 CUU99319.1 - 4e-12 46.5 0.1 7.6e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 RNase H PAH PF02671.21 CUU99320.1 - 0.031 14.4 1.1 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat TMA7 PF09072.10 CUU99320.1 - 0.44 11.4 0.1 0.44 11.4 0.1 1.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 Innexin PF00876.18 CUU99323.1 - 6.3e-47 160.6 3.2 7.8e-47 160.3 3.2 1.0 1 0 0 1 1 1 1 Innexin HLH PF00010.26 CUU99327.1 - 1.3e-13 50.6 0.4 2e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain eIF3_subunit PF08597.10 CUU99327.1 - 0.048 13.6 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cas9-BH PF16593.5 CUU99327.1 - 0.066 13.0 2.8 0.17 11.7 2.8 1.6 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Pkinase PF00069.25 CUU99328.1 - 5.8e-36 124.2 0.0 6.6e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99328.1 - 4e-20 72.2 0.0 4.5e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CUU99328.1 - 0.00014 20.9 0.1 0.00018 20.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CUU99328.1 - 0.0026 17.2 0.2 0.0034 16.8 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CUU99328.1 - 0.0032 16.8 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CUU99328.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CUU99328.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_polyA_pol_C PF12629.7 CUU99329.1 - 0.095 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain MraZ PF02381.18 CUU99330.1 - 0.24 11.4 0.8 12 6.0 0.2 2.2 1 1 1 2 2 2 0 MraZ protein, putative antitoxin-like Ribosomal_S26e PF01283.19 CUU99332.1 - 1.6e-30 105.7 2.3 2e-30 105.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e CxxCxxCC PF03692.15 CUU99332.1 - 0.0048 17.5 1.2 0.0057 17.3 1.2 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain NTR PF01759.21 CUU99333.1 - 3.6e-10 39.6 0.1 3.9e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 UNC-6/NTR/C345C module PAC4 PF16093.5 CUU99335.1 - 0.0025 17.9 0.4 0.021 15.0 0.1 2.0 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 PAC4 PF16093.5 CUU99336.1 - 0.016 15.4 2.4 0.036 14.2 0.1 2.3 3 0 0 3 3 3 0 Proteasome assembly chaperone 4 zf-TFIIB PF13453.6 CUU99341.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger VP_N-CPKC PF11475.8 CUU99341.1 - 0.16 11.9 0.3 0.16 11.9 0.3 2.2 3 0 0 3 3 3 0 Virion protein N terminal domain zf-C2H2 PF00096.26 CUU99342.1 - 1.8e-29 100.5 29.8 8.3e-06 26.0 0.6 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99342.1 - 6.1e-20 70.2 29.4 0.00016 22.2 0.3 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU99342.1 - 3e-16 59.0 31.5 1.4e-06 28.5 0.1 6.1 7 1 0 7 7 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CUU99342.1 - 1.1e-11 44.7 16.7 0.019 15.2 0.0 5.2 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CUU99342.1 - 6.5e-11 42.2 19.1 0.0022 18.3 0.2 5.1 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CUU99342.1 - 4.1e-10 39.4 25.2 0.0027 17.7 0.2 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 CUU99342.1 - 9.2e-08 32.4 18.3 0.0062 17.0 0.0 5.1 2 1 3 5 5 5 3 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 CUU99342.1 - 0.00016 21.9 18.3 0.23 11.8 5.6 3.2 1 1 2 3 3 3 3 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 CUU99342.1 - 0.0088 16.8 0.6 0.0088 16.8 0.6 3.3 2 1 1 3 3 3 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 CUU99342.1 - 0.0095 16.0 20.7 0.043 13.9 0.5 4.3 3 1 1 4 4 4 2 Zinc ribbon domain zf-C2H2_2 PF12756.7 CUU99342.1 - 0.013 15.9 20.4 0.3 11.4 0.6 4.8 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CUU99342.1 - 0.013 15.2 25.3 0.88 9.4 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf_ZIC PF18366.1 CUU99342.1 - 0.022 14.9 7.9 7.6 6.7 0.0 4.6 1 1 3 4 4 4 0 Zic proteins zinc finger domain DUF4764 PF15961.5 CUU99342.1 - 0.023 13.4 7.7 0.036 12.8 7.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) C1_4 PF07975.12 CUU99342.1 - 0.054 13.7 0.7 0.054 13.7 0.7 4.0 3 1 1 4 4 4 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 CUU99342.1 - 0.061 13.2 0.3 0.061 13.2 0.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CUU99342.1 - 0.31 11.1 28.6 0.8 9.8 0.3 5.3 3 1 2 5 5 5 0 BED zinc finger zf-AN1 PF01428.16 CUU99342.1 - 0.42 10.8 21.2 18 5.6 0.5 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger Zf_RING PF16744.5 CUU99342.1 - 0.51 10.5 20.6 0.57 10.3 0.9 4.4 2 1 3 5 5 5 0 KIAA1045 RING finger HypA PF01155.19 CUU99342.1 - 1 9.4 18.3 0.79 9.8 0.8 3.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 CUU99342.1 - 1.1 8.9 0.1 1.1 8.9 0.1 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 CUU99342.1 - 1.2 9.2 18.8 3.7 7.7 0.1 5.0 5 0 0 5 5 5 0 XPA protein N-terminal ADK_lid PF05191.14 CUU99342.1 - 1.8 8.6 15.3 2.1 8.4 0.1 4.1 4 1 0 4 4 4 0 Adenylate kinase, active site lid Spt46 PF17734.1 CUU99342.1 - 2.7 7.8 16.0 0.52 10.1 0.9 3.9 1 1 3 4 4 4 0 Spermatogenesis-associated protein 46 zf-LYAR PF08790.11 CUU99342.1 - 3.2 7.7 12.4 0.67 9.9 0.3 4.4 4 1 1 5 5 5 0 LYAR-type C2HC zinc finger LIM PF00412.22 CUU99342.1 - 4.7 7.5 22.0 1.7 8.9 2.9 4.2 2 1 2 4 4 4 0 LIM domain zf_C2H2_13 PF18508.1 CUU99342.1 - 5.7 6.6 10.4 15 5.2 0.2 4.0 3 1 1 4 4 4 0 Zinc finger domain DUF2256 PF10013.9 CUU99342.1 - 8.3 6.6 18.1 2.1 8.5 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2 PF00096.26 CUU99343.1 - 3.9e-28 96.3 29.8 1.6e-05 25.1 0.6 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99343.1 - 1.4e-18 65.9 29.4 0.00032 21.3 0.3 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU99343.1 - 2.1e-17 62.6 23.1 2.7e-06 27.5 0.1 6.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CUU99343.1 - 8.9e-11 41.8 16.2 0.038 14.3 0.0 5.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CUU99343.1 - 8.5e-10 38.7 19.7 0.0042 17.4 0.2 5.5 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CUU99343.1 - 8.5e-09 35.2 25.2 0.0053 16.7 0.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HE PF16278.5 CUU99343.1 - 1.5e-07 31.7 14.8 0.014 15.8 0.0 5.3 2 1 3 5 5 5 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 CUU99343.1 - 0.011 16.0 21.6 0.66 10.3 5.7 3.7 2 1 2 4 4 4 0 C2H2-type zinc ribbon zinc_ribbon_15 PF17032.5 CUU99343.1 - 0.02 15.7 0.6 0.02 15.7 0.6 3.3 2 1 0 2 2 1 0 zinc-ribbon family DUF4764 PF15961.5 CUU99343.1 - 0.059 12.1 7.2 0.1 11.3 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) Zn-ribbon_8 PF09723.10 CUU99343.1 - 0.084 13.0 0.5 0.084 13.0 0.5 4.3 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 CUU99343.1 - 0.12 12.3 0.3 0.12 12.3 0.3 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 CUU99343.1 - 0.2 11.8 7.8 15 5.8 0.0 4.5 1 1 3 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 CUU99343.1 - 0.25 11.1 25.3 1.7 8.5 0.6 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CUU99343.1 - 0.38 11.1 20.9 0.43 10.9 0.5 4.7 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.12 CUU99343.1 - 1.6 9.0 18.0 0.23 11.7 1.6 3.9 3 1 0 3 3 3 0 TFIIH C1-like domain Zf_RING PF16744.5 CUU99343.1 - 3.3 7.9 19.7 1.8 8.7 1.6 4.1 2 1 3 5 5 5 0 KIAA1045 RING finger HypA PF01155.19 CUU99343.1 - 6.2 6.9 17.6 2.8e+02 1.5 9.4 3.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 CUU99343.1 - 6.5 6.9 28.5 2.6 8.1 1.2 5.3 3 1 1 4 4 4 0 BED zinc finger FYVE PF01363.21 CUU99343.1 - 7.8 6.7 24.6 2.9e+02 1.7 5.6 4.1 1 1 2 3 3 3 0 FYVE zinc finger zf-AN1 PF01428.16 CUU99343.1 - 9.4 6.5 21.4 34 4.7 0.5 5.4 5 0 0 5 5 5 0 AN1-like Zinc finger Sod_Cu PF00080.20 CUU99344.1 - 2.5e-48 163.9 4.1 2.7e-48 163.8 4.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SPAN PF02510.14 CUU99344.1 - 0.098 11.8 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein Lactamase_B_4 PF13691.6 CUU99345.1 - 1.9e-07 30.6 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 tRNase Z endonuclease bZIP_Maf PF03131.17 CUU99348.1 - 8.2e-05 23.0 6.8 8.2e-05 23.0 6.8 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CUU99348.1 - 3 8.0 16.5 0.11 12.6 9.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor Transglut_core3 PF13471.6 CUU99349.1 - 0.025 14.5 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Transglut_core3 PF13471.6 CUU99350.1 - 0.025 14.5 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Lig_chan PF00060.26 CUU99352.1 - 4.8e-30 104.4 0.1 1.1e-29 103.2 0.1 1.7 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CUU99352.1 - 2.4e-23 82.5 0.0 7.7e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CUU99352.1 - 2e-10 40.5 0.0 1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 CUU99352.1 - 0.015 15.2 0.3 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 Ion channel DUF2023 PF09633.10 CUU99352.1 - 0.038 14.1 0.0 3.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2023) Lig_chan-Glu_bd PF10613.9 CUU99353.1 - 5e-24 84.7 0.0 6.5e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CUU99353.1 - 1.3e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Pkinase PF00069.25 CUU99354.1 - 1.2e-31 110.1 0.0 2.4e-30 105.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99354.1 - 1.5e-19 70.4 0.0 1.9e-18 66.7 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase AAA_6 PF12774.7 CUU99356.1 - 7.3e-145 482.0 0.1 4.5e-144 479.4 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CUU99356.1 - 6.9e-118 394.2 6.0 6.9e-118 394.2 6.0 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CUU99356.1 - 1.1e-109 367.6 4.5 1.1e-109 367.6 4.5 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CUU99356.1 - 1.7e-89 299.6 0.1 7.8e-89 297.4 0.0 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CUU99356.1 - 3.1e-79 265.2 3.1 5.5e-79 264.3 0.2 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CUU99356.1 - 5.9e-70 234.5 2.5 2.8e-64 215.9 0.2 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CUU99356.1 - 1.5e-55 187.5 0.1 3.7e-55 186.2 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CUU99356.1 - 9.4e-46 156.4 9.3 1.9e-45 155.4 9.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CUU99356.1 - 1.1e-42 144.9 0.1 3.3e-41 140.1 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CUU99356.1 - 6.5e-25 87.7 0.0 2.3e-08 34.1 0.0 5.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CUU99356.1 - 4.3e-18 65.6 0.1 2.9e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CUU99356.1 - 2.3e-06 27.7 0.2 3.8e-05 23.8 0.0 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CUU99356.1 - 5.9e-06 26.7 0.0 1.6 9.2 0.0 4.4 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Dynein_C PF18199.1 CUU99356.1 - 0.001 18.4 0.7 0.0047 16.2 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_22 PF13401.6 CUU99356.1 - 0.0017 18.7 1.5 42 4.4 0.0 5.6 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 CUU99356.1 - 0.0043 17.2 0.7 4.7 7.4 0.0 4.7 4 0 0 4 4 4 1 AAA domain DUF1048 PF06304.11 CUU99356.1 - 0.043 14.3 0.0 1.7 9.2 0.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) VasL PF12486.8 CUU99356.1 - 0.057 13.3 1.1 14 5.6 0.1 3.0 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL DUF4298 PF14131.6 CUU99356.1 - 0.079 12.9 5.9 4.5 7.3 0.0 5.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) AAA_29 PF13555.6 CUU99356.1 - 0.13 12.0 0.4 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain Spc7 PF08317.11 CUU99356.1 - 0.23 10.3 26.4 0.24 10.3 4.2 3.8 3 0 0 3 3 3 0 Spc7 kinetochore protein H_PPase PF03030.16 CUU99356.1 - 0.28 9.8 0.0 0.43 9.1 0.0 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase UPF0242 PF06785.11 CUU99356.1 - 0.69 10.0 23.3 0.033 14.3 1.5 4.3 4 0 0 4 4 3 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 CUU99356.1 - 1.7 9.0 24.2 0.0094 16.4 1.6 3.9 3 0 0 3 3 3 0 Fez1 HrpB7 PF09486.10 CUU99356.1 - 6 7.2 24.2 2.9 8.2 4.7 3.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) AAA_16 PF13191.6 CUU99356.1 - 6.2 7.2 13.5 35 4.7 0.0 6.0 7 0 0 7 7 5 0 AAA ATPase domain Dynein_C PF18199.1 CUU99357.1 - 1.8e-31 109.5 0.0 2e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain TFIID-18kDa PF02269.16 CUU99358.1 - 4.9e-29 100.2 0.1 6.1e-29 99.9 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Apc13p PF05839.11 CUU99359.1 - 0.00011 22.3 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Apc13p protein Gal_Lectin PF02140.18 CUU99360.1 - 0.00099 19.5 7.6 0.0043 17.5 1.6 3.6 3 1 0 3 3 3 1 Galactose binding lectin domain Adeno_E3_CR2 PF02439.15 CUU99360.1 - 0.0038 17.0 1.5 0.0081 15.9 1.5 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4381 PF14316.6 CUU99360.1 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) FAM176 PF14851.6 CUU99360.1 - 0.078 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 FAM176 family LRRC37AB_C PF14914.6 CUU99360.1 - 0.1 12.5 0.5 3.9 7.4 0.0 2.5 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain TMEM51 PF15345.6 CUU99360.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 51 SBP_bac_3 PF00497.20 CUU99362.1 - 4.7e-08 32.7 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 FAM176 PF14851.6 CUU99362.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Lig_chan PF00060.26 CUU99362.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel OSTbeta PF15048.6 CUU99362.1 - 0.14 12.3 0.3 0.26 11.4 0.2 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Pyrid_ox_like PF16242.5 CUU99363.1 - 5e-06 26.2 0.1 7.2e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like FOXP-CC PF16159.5 CUU99364.1 - 0.015 15.9 0.1 0.044 14.4 0.1 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain TMCO5 PF14992.6 CUU99364.1 - 0.26 10.8 2.6 0.48 10.0 2.6 1.3 1 0 0 1 1 1 0 TMCO5 family Exonuc_VII_L PF02601.15 CUU99364.1 - 0.57 9.7 3.7 1.1 8.8 3.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCDC106 PF15794.5 CUU99364.1 - 0.75 9.5 0.0 0.75 9.5 0.0 5.1 6 0 0 6 6 6 0 Coiled-coil domain-containing protein 106 ADIP PF11559.8 CUU99364.1 - 1.1 9.3 9.2 0.85 9.7 5.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 CUU99364.1 - 2.5 9.1 5.0 1.2e+02 3.7 4.7 3.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Pou PF00157.17 CUU99365.1 - 2.7e-27 94.5 0.0 6.4e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CUU99365.1 - 5.1e-23 80.7 4.9 1.6e-15 56.6 0.5 2.6 2 0 0 2 2 2 2 Homeodomain HTH_Tnp_Tc3_1 PF11427.8 CUU99365.1 - 0.00064 19.5 0.2 0.36 10.7 0.0 2.8 3 0 0 3 3 3 2 Tc3 transposase Homeobox_KN PF05920.11 CUU99365.1 - 0.00078 19.3 1.2 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 Homeobox KN domain DUF1547 PF07577.11 CUU99365.1 - 0.17 12.3 1.0 19 5.7 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) DM PF00751.18 CUU99366.1 - 2.4e-21 75.3 8.9 4.3e-21 74.5 8.9 1.4 1 0 0 1 1 1 1 DM DNA binding domain zf-C3HC PF07967.13 CUU99366.1 - 0.0061 16.6 0.3 0.014 15.5 0.3 1.5 1 0 0 1 1 1 1 C3HC zinc finger-like AROS PF15684.5 CUU99368.1 - 0.035 14.7 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 zf-RVT PF13966.6 CUU99368.1 - 0.15 12.8 1.5 0.17 12.6 1.5 1.3 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF2777 PF10949.8 CUU99370.1 - 0.12 12.1 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) CIAPIN1 PF05093.13 CUU99371.1 - 2.7e-23 82.4 13.6 1.8e-20 73.3 13.6 2.4 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Tat PF00539.18 CUU99371.1 - 0.34 11.1 6.2 6.7 6.9 1.4 2.4 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) UCR_6-4kD PF08997.10 CUU99373.1 - 3.9e-09 36.3 0.1 4.7e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein VWA PF00092.28 CUU99374.1 - 3e-39 135.1 2.1 2e-18 67.3 0.2 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CUU99374.1 - 1.6e-23 83.4 0.4 3.6e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain PCI PF01399.27 CUU99374.1 - 1.1e-15 58.0 0.0 3.5e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 CUU99374.1 - 1.9e-09 38.0 2.6 7.2e-08 32.9 2.6 2.7 1 1 0 1 1 1 1 eIF3 subunit 6 N terminal domain RPN7 PF10602.9 CUU99374.1 - 0.002 17.8 0.3 0.0044 16.7 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF3247 PF11607.8 CUU99374.1 - 0.0055 16.9 0.0 8.3 6.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3247) cNMP_binding PF00027.29 CUU99375.1 - 1.3e-43 147.0 0.0 6e-22 77.5 0.0 2.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CUU99375.1 - 1.9e-06 27.4 0.0 5.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CUU99375.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif DUF5582 PF17819.1 CUU99375.1 - 0.1 13.1 0.6 0.24 11.8 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5582) Pkinase_Tyr PF07714.17 CUU99376.1 - 1.8e-70 237.2 0.0 2.9e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU99376.1 - 4e-40 137.8 0.0 6.1e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANF_receptor PF01094.28 CUU99376.1 - 4.1e-22 78.8 0.6 7e-22 78.0 0.6 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Kinase-like PF14531.6 CUU99376.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Glycos_transf_2 PF00535.26 CUU99377.1 - 1.5e-27 96.5 0.0 3e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CUU99377.1 - 2.5e-09 37.0 0.0 1.1e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CUU99377.1 - 7.9e-08 31.8 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 CUU99377.1 - 9.1e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 CUU99377.1 - 0.00045 20.5 0.2 0.0011 19.2 0.2 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CUU99377.1 - 0.0038 17.9 0.1 0.019 15.7 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like C5-epim_C PF06662.13 CUU99378.1 - 1.5e-42 145.2 0.0 6.2e-38 130.2 0.0 2.3 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus NCU-G1 PF15065.6 CUU99379.1 - 1.7e-25 89.8 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 PhoPQ_related PF10142.9 CUU99379.1 - 0.18 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein RRM_1 PF00076.22 CUU99380.1 - 2.4e-18 65.7 0.0 3.8e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4536 PF15055.6 CUU99381.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Wtap PF17098.5 CUU99382.1 - 4.5e-05 23.4 0.2 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 WTAP/Mum2p family Ccdc124 PF06244.12 CUU99382.1 - 0.00027 21.5 1.7 0.74 10.4 0.1 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 124 /Oxs1 DoxX_2 PF13564.6 CUU99382.1 - 0.0009 19.3 0.5 0.0013 18.8 0.5 1.2 1 0 0 1 1 1 1 DoxX-like family DUF2312 PF10073.9 CUU99382.1 - 0.02 14.6 2.1 5 6.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) GRIN_C PF15235.6 CUU99382.1 - 0.023 15.0 2.5 5.2 7.3 0.2 2.3 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Fzo_mitofusin PF04799.13 CUU99382.1 - 0.052 13.1 2.5 5.7 6.5 0.2 2.3 2 0 0 2 2 2 0 fzo-like conserved region DUF4164 PF13747.6 CUU99382.1 - 0.14 12.5 1.0 21 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Ribosomal_L18p PF00861.22 CUU99382.1 - 0.22 11.9 1.8 20 5.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Occludin_ELL PF07303.13 CUU99382.1 - 0.25 12.1 8.9 3 8.6 0.5 2.4 3 0 0 3 3 2 0 Occludin homology domain KASH_CCD PF14662.6 CUU99382.1 - 0.37 10.6 8.0 4.2 7.2 1.0 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CUU99382.1 - 1.1 9.4 5.4 14 5.8 0.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 CUU99382.1 - 1.9 8.6 9.4 8.3 6.5 1.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Glycophorin_A PF01102.18 CUU99384.1 - 0.0056 16.9 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 CUU99384.1 - 0.012 15.5 0.7 0.027 14.4 0.7 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 CUU99384.1 - 0.16 11.4 3.5 0.49 9.8 3.7 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 CUU99384.1 - 1.4 8.7 9.1 3.4 7.5 9.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1514 PF07438.11 CUU99384.1 - 7 6.6 5.8 40 4.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) zf_CCCH_4 PF18345.1 CUU99385.1 - 3.3e-09 36.5 23.7 9.3e-08 31.9 4.3 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CUU99385.1 - 4e-09 36.2 19.3 6.9e-07 29.0 3.1 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CUU99385.1 - 1.7e-05 24.5 24.2 0.00065 19.4 5.6 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CUU99385.1 - 0.00045 20.9 10.4 0.003 18.2 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CUU99385.1 - 0.00096 19.5 19.9 0.12 12.9 2.7 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CUU99385.1 - 0.027 14.7 4.7 1.3 9.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Rhodanese PF00581.20 CUU99386.1 - 4.7e-14 52.8 0.0 5.2e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain PTPlike_phytase PF14566.6 CUU99386.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate SR-25 PF10500.9 CUU99387.1 - 0.054 13.1 7.0 0.069 12.8 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG16 PF08614.11 CUU99387.1 - 0.057 13.7 0.7 0.075 13.3 0.7 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IMUP PF15761.5 CUU99387.1 - 0.18 12.5 7.9 0.26 12.0 7.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Alpha_adaptinC2 PF02883.20 CUU99391.1 - 6.6e-21 74.7 1.3 1.4e-20 73.7 1.3 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Adaptin_N PF01602.20 CUU99391.1 - 6.7e-11 41.4 0.1 9.2e-11 41.0 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region TSP_1 PF00090.19 CUU99394.1 - 2.3e-14 53.3 11.2 2.7e-08 33.9 0.5 4.0 3 1 0 3 3 3 2 Thrombospondin type 1 domain DnaJ PF00226.31 CUU99395.1 - 1.1e-24 86.3 0.2 1.1e-24 86.3 0.2 2.5 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 CUU99395.1 - 0.0033 17.4 0.1 0.0074 16.3 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Mu-like_Pro PF10123.9 CUU99395.1 - 0.025 14.2 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein TPR_1 PF00515.28 CUU99395.1 - 0.08 12.8 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GPCR_chapero_1 PF11904.8 CUU99396.1 - 3.3e-21 76.0 0.1 5.2e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 GPCR-chaperone MFS_1 PF07690.16 CUU99399.1 - 8.1e-30 103.9 17.8 8.1e-30 103.9 17.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2457 PF10446.9 CUU99399.1 - 4.9 6.2 6.9 7 5.7 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pro_dh PF01619.18 CUU99400.1 - 0.089 12.3 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Proline dehydrogenase FAM92 PF06730.11 CUU99401.1 - 5e-45 153.6 8.2 7.9e-45 153.0 8.2 1.2 1 0 0 1 1 1 1 FAM92 protein BAR_3 PF16746.5 CUU99401.1 - 1.9e-05 24.5 6.0 1.9e-05 24.5 6.0 2.1 2 0 0 2 2 2 1 BAR domain of APPL family RNA_polI_A14 PF08203.11 CUU99401.1 - 0.25 12.1 0.2 0.25 12.1 0.2 3.0 3 1 1 4 4 4 0 Yeast RNA polymerase I subunit RPA14 ZapB PF06005.12 CUU99404.1 - 0.0045 17.4 3.2 2.6 8.5 0.7 2.8 2 1 2 4 4 4 4 Cell division protein ZapB bZIP_1 PF00170.21 CUU99404.1 - 0.0065 16.5 1.8 0.099 12.8 0.2 2.4 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 CUU99404.1 - 0.028 14.2 1.4 0.92 9.3 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator TolA_bind_tri PF16331.5 CUU99404.1 - 0.16 12.1 2.0 20 5.4 0.0 2.5 2 1 0 2 2 2 0 TolA binding protein trimerisation Lig_chan PF00060.26 CUU99405.1 - 2.8e-68 228.5 1.4 1.7e-50 170.8 0.2 2.3 2 0 0 2 2 2 2 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CUU99405.1 - 4e-46 155.9 1.2 2.4e-33 114.8 0.2 2.4 2 0 0 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CUU99405.1 - 3.9e-29 101.7 0.0 2.4e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 CUU99405.1 - 0.0077 16.2 2.1 0.0077 16.2 2.1 4.3 5 0 0 5 5 5 1 Ion channel DUF3094 PF11293.8 CUU99405.1 - 0.018 14.8 0.4 9 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DUF3397 PF11877.8 CUU99405.1 - 0.22 11.8 3.2 34 4.7 0.1 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF3397) HCO3_cotransp PF00955.21 CUU99406.1 - 8.8e-83 278.8 5.3 1.1e-82 278.5 5.3 1.0 1 0 0 1 1 1 1 HCO3- transporter family TMEM223 PF14640.6 CUU99406.1 - 0.022 14.9 0.0 0.067 13.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 223 Sulfate_transp PF00916.20 CUU99406.1 - 0.053 12.3 4.8 0.84 8.3 0.8 2.3 2 0 0 2 2 2 0 Sulfate permease family Toxin_33 PF08121.11 CUU99406.1 - 2.4 8.0 7.1 2.6 7.9 0.9 2.3 2 0 0 2 2 2 0 Waglerin family MIG-14_Wnt-bd PF06664.12 CUU99407.1 - 4.1e-43 147.7 31.6 7.2e-43 146.9 31.6 1.4 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF86 PF01934.17 CUU99409.1 - 0.067 13.1 1.9 0.13 12.1 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 GrpE PF01025.19 CUU99409.1 - 0.3 10.8 8.9 3.8 7.1 8.8 2.1 1 1 0 1 1 1 0 GrpE DUF2408 PF10303.9 CUU99409.1 - 0.41 11.2 7.5 2 8.9 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Ribosomal_S24e PF01282.19 CUU99411.1 - 1.6e-34 117.6 0.8 2.1e-34 117.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e YidD PF01809.18 CUU99413.1 - 0.012 15.5 2.3 0.11 12.4 0.6 2.1 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor Ras PF00071.22 CUU99415.1 - 3.7e-33 114.4 0.1 5e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CUU99415.1 - 2.9e-26 92.0 0.0 3.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CUU99415.1 - 3.1e-09 36.5 0.0 3.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CUU99415.1 - 4.1e-07 30.1 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CUU99415.1 - 6.2e-07 29.0 0.0 8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CUU99415.1 - 0.0016 17.9 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CUU99415.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CUU99415.1 - 0.0023 17.9 0.1 0.0041 17.0 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CUU99415.1 - 0.0042 17.5 0.0 0.0054 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CUU99415.1 - 0.0054 16.5 0.1 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CUU99415.1 - 0.0077 16.7 0.4 0.019 15.5 0.1 1.7 2 1 0 2 2 1 1 ABC transporter PduV-EutP PF10662.9 CUU99415.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CUU99415.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CUU99415.1 - 0.033 14.5 0.2 0.2 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CUU99415.1 - 0.041 13.0 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 CUU99415.1 - 0.045 12.9 0.2 4.2 6.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 CUU99415.1 - 0.049 13.6 0.1 0.15 12.1 0.1 1.9 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CUU99415.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CUU99415.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CUU99415.1 - 0.16 11.8 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain VWA_3 PF13768.6 CUU99416.1 - 2.1e-19 70.0 0.0 3.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 CUU99416.1 - 1.1e-18 67.4 0.4 2.1e-18 66.6 0.4 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 CUU99416.1 - 6.7e-12 46.0 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CUU99416.1 - 9.9e-11 42.3 0.0 2.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 CUU99416.1 - 5.4e-08 32.6 0.1 1.2e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 CUU99416.1 - 8.3e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus CobT_C PF11775.8 CUU99416.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Lactamase_B PF00753.27 CUU99417.1 - 0.018 15.0 0.0 0.025 14.6 0.0 1.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily MT-A70 PF05063.14 CUU99418.1 - 2.4e-50 170.8 0.1 5.2e-50 169.7 0.1 1.6 1 1 0 1 1 1 1 MT-A70 Ku_PK_bind PF08785.11 CUU99419.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Fer2 PF00111.27 CUU99421.1 - 3.2e-09 36.6 0.1 4.5e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SET PF00856.28 CUU99422.1 - 3.7e-09 37.2 0.0 1.7e-08 35.0 0.0 2.3 2 1 0 2 2 2 1 SET domain RNase_H PF00075.24 CUU99423.1 - 3.8e-05 23.9 0.2 0.00013 22.2 0.0 2.1 2 1 0 2 2 2 1 RNase H RNase_H PF00075.24 CUU99424.1 - 3.8e-05 23.9 0.2 0.00013 22.2 0.0 2.1 2 1 0 2 2 2 1 RNase H Mob1_phocein PF03637.17 CUU99425.1 - 2.8e-24 86.0 0.7 3.5e-24 85.7 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family UPRTase PF14681.6 CUU99426.1 - 1.4e-28 99.7 0.2 1.6e-28 99.6 0.2 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Flavi_NS2B PF01002.19 CUU99426.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B SNARE PF05739.19 CUU99429.1 - 5.5e-16 58.3 1.1 5.5e-16 58.3 1.1 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CUU99429.1 - 8.1e-07 28.9 6.4 8.1e-07 28.9 6.4 2.1 2 1 0 2 2 2 1 Syntaxin DUF1818 PF08848.11 CUU99429.1 - 0.0054 16.8 6.4 1.1 9.3 0.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1818) DUF5345 PF17280.2 CUU99429.1 - 0.0074 16.2 0.4 0.027 14.4 0.4 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5345) Goodbye PF17109.5 CUU99429.1 - 0.033 14.6 0.7 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain MCPsignal PF00015.21 CUU99429.1 - 0.039 13.8 1.6 0.34 10.7 0.4 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF5527 PF17665.1 CUU99429.1 - 0.047 13.2 1.3 0.051 13.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DUF2157 PF09925.9 CUU99429.1 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) TMPIT PF07851.13 CUU99429.1 - 0.065 12.5 4.6 1.6 7.9 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DDE_Tnp_IS240 PF13610.6 CUU99429.1 - 0.073 13.3 0.4 0.14 12.4 0.1 1.6 2 1 0 2 2 2 0 DDE domain ING PF12998.7 CUU99429.1 - 0.1 13.2 9.7 0.085 13.5 0.6 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 CUU99429.1 - 0.14 12.3 8.0 0.16 12.0 0.1 3.3 4 0 0 4 4 4 0 Swi5 Syntaxin_2 PF14523.6 CUU99429.1 - 0.47 10.9 12.9 0.31 11.4 3.8 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.11 CUU99429.1 - 0.65 10.3 7.1 87 3.5 6.9 3.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 CUU99429.1 - 2 9.1 5.9 12 6.6 2.6 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2933 PF11666.8 CUU99431.1 - 1 9.4 4.8 10 6.3 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) EF-hand_1 PF00036.32 CUU99433.1 - 1.6e-11 42.9 0.1 5.1e-06 25.6 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CUU99433.1 - 2e-11 44.2 0.3 0.00032 21.1 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CUU99433.1 - 4.2e-10 39.3 0.4 2.6e-05 24.0 0.0 4.0 3 2 2 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 CUU99433.1 - 2.6e-08 33.1 0.1 0.0022 17.8 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CUU99433.1 - 6.4e-07 28.6 0.2 4.7e-05 22.7 0.1 3.0 3 0 0 3 3 3 1 EF hand VCPO_N PF17897.1 CUU99433.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain ANAPC4_WD40 PF12894.7 CUU99436.1 - 3.3e-05 24.1 0.0 0.00084 19.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CUU99436.1 - 0.0016 19.3 5.9 0.57 11.1 0.1 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat Herpes_UL69 PF05459.12 CUU99437.1 - 0.054 12.8 0.2 0.069 12.5 0.2 1.4 1 1 0 1 1 1 0 Herpesvirus transcriptional regulator family PKcGMP_CC PF16808.5 CUU99438.1 - 7.1e-05 22.6 1.8 7.1e-05 22.6 1.8 1.8 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 CUU99438.1 - 0.022 14.9 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CENP-R PF06729.12 CUU99438.1 - 0.071 13.0 1.2 0.14 12.1 1.2 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R PKcGMP_CC PF16808.5 CUU99439.1 - 7.1e-05 22.6 1.8 7.1e-05 22.6 1.8 1.8 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 CUU99439.1 - 0.022 14.9 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component CENP-R PF06729.12 CUU99439.1 - 0.071 13.0 1.2 0.14 12.1 1.2 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R BATS PF06968.13 CUU99441.1 - 0.11 12.6 0.0 23 5.2 0.0 2.8 3 0 0 3 3 3 0 Biotin and Thiamin Synthesis associated domain Toxin_30 PF08117.11 CUU99441.1 - 1.7 9.0 3.7 5.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Ptu family EF-hand_7 PF13499.6 CUU99442.1 - 0.089 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Anoct_dimer PF16178.5 CUU99443.1 - 2.2e-16 60.3 0.0 3.8e-16 59.5 0.0 1.3 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin rve PF00665.26 CUU99444.1 - 7.7e-23 81.0 0.0 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CUU99444.1 - 2.6e-16 59.5 1.7 2.6e-16 59.5 1.7 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CUU99444.1 - 0.00031 20.5 0.0 0.0009 19.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CUU99444.1 - 0.0005 20.2 0.2 0.0011 19.1 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_IS240 PF13610.6 CUU99444.1 - 0.0088 16.3 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain DDE_Tnp_IS1595 PF12762.7 CUU99444.1 - 0.095 12.7 0.0 15 5.6 0.0 2.2 2 0 0 2 2 2 0 ISXO2-like transposase domain RVT_1 PF00078.27 CUU99445.1 - 6.2e-11 42.2 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CUU99445.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CUU99445.1 - 0.18 12.5 0.0 0.39 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2_4 PF13894.6 CUU99447.1 - 0.0027 18.4 3.0 0.015 16.1 0.4 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.12 CUU99447.1 - 0.0084 16.4 3.6 0.029 14.7 3.7 1.8 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CUU99447.1 - 0.033 14.5 0.6 0.048 14.0 0.6 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 CUU99447.1 - 0.051 12.1 0.5 0.06 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) MCD PF05292.11 CUU99447.1 - 0.064 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain zf-C2H2 PF00096.26 CUU99447.1 - 0.071 13.6 0.6 0.071 13.6 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 CUU99447.1 - 0.11 12.4 4.7 2.8 7.9 0.0 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 CUU99447.1 - 0.12 12.3 2.3 0.15 12.0 0.3 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF2162 PF09930.9 CUU99447.1 - 0.26 10.7 0.1 0.29 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) zf-C2H2_12 PF18658.1 CUU99447.1 - 0.34 10.5 2.4 2 8.1 0.2 2.3 2 1 0 2 2 2 0 Zinc-finger C2H2-type DUF4512 PF14975.6 CUU99448.1 - 4.3e-06 27.4 7.1 4.3e-06 27.4 7.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4512) Ribonuclease_3 PF00636.26 CUU99449.1 - 5.9e-47 158.6 0.0 1.2e-23 83.8 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CUU99449.1 - 1.2e-23 83.6 0.0 7.8e-16 58.4 0.0 2.7 2 1 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.29 CUU99449.1 - 2.9e-16 59.8 0.0 5.2e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Dicer_dimer PF03368.14 CUU99449.1 - 3e-15 56.2 0.0 7.2e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 CUU99449.1 - 7e-12 45.7 0.1 2e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CUU99449.1 - 1.4e-11 44.7 0.0 2.1e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit MlaE PF02405.16 CUU99449.1 - 0.028 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Permease MlaE ChuX_HutX PF06228.13 CUU99449.1 - 0.21 11.4 0.1 43 3.9 0.0 2.9 3 0 0 3 3 3 0 Haem utilisation ChuX/HutX DUF3613 PF12266.8 CUU99449.1 - 0.27 11.0 2.6 19 5.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) UBX PF00789.20 CUU99450.1 - 2.6e-12 46.8 0.4 1.1e-06 28.8 0.1 2.8 2 0 0 2 2 2 2 UBX domain Biotin_carb_N PF00289.22 CUU99450.1 - 0.014 15.9 0.2 84 3.8 0.0 3.6 3 0 0 3 3 3 0 Biotin carboxylase, N-terminal domain CID_GANP PF16766.5 CUU99450.1 - 0.023 14.9 5.0 31 4.9 0.1 3.8 3 0 0 3 3 3 0 Binding region of GANP to ENY2 UBA_4 PF14555.6 CUU99450.1 - 0.11 12.4 0.5 0.28 11.0 0.5 1.7 1 0 0 1 1 1 0 UBA-like domain Mito_fiss_reg PF05308.11 CUU99450.1 - 3.3 7.7 14.0 6.6 6.7 2.3 2.9 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF2651 PF10852.8 CUU99450.1 - 4.2 8.0 4.9 1.9e+02 2.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) RVT_1 PF00078.27 CUU99453.1 - 2.6e-06 27.1 0.0 3.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BTB_2 PF02214.22 CUU99460.1 - 9.8e-28 96.4 0.0 1.8e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CUU99460.1 - 0.0022 18.1 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain CENP-F_C_Rb_bdg PF10490.9 CUU99462.1 - 0.038 13.4 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Paxillin PF03535.13 CUU99462.1 - 0.046 13.6 0.7 6.9 6.5 0.1 2.1 1 1 0 2 2 2 0 Paxillin family TALPID3 PF15324.6 CUU99462.1 - 2.7 5.5 6.4 5.8 4.4 0.7 2.0 1 1 0 2 2 2 0 Hedgehog signalling target Dynein_light PF01221.18 CUU99463.1 - 5e-21 74.8 0.0 5.6e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 dNK PF01712.19 CUU99465.1 - 7.3e-21 75.0 2.1 2e-20 73.5 2.1 1.7 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_17 PF13207.6 CUU99465.1 - 0.01 16.3 0.1 1.1 9.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CUU99465.1 - 0.061 13.9 0.0 0.36 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CUU99465.1 - 0.076 13.2 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CUU99465.1 - 0.086 12.8 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_C6 PF00851.18 CUU99466.1 - 0.039 12.9 0.1 0.041 12.8 0.1 1.0 1 0 0 1 1 1 0 Helper component proteinase Rod_C PF10493.9 CUU99471.1 - 0.0056 15.1 0.3 0.0081 14.6 0.3 1.1 1 0 0 1 1 1 1 Rough deal protein C-terminal region Cellulose_synt PF03552.14 CUU99471.1 - 0.038 12.5 0.4 0.072 11.6 0.4 1.4 1 0 0 1 1 1 0 Cellulose synthase DUF4149 PF13664.6 CUU99471.1 - 0.64 10.4 9.0 0.086 13.2 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) PCSK9_C3 PF18463.1 CUU99472.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain CTP_transf_like PF01467.26 CUU99473.1 - 0.0021 18.2 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like HECT PF00632.25 CUU99474.1 - 6.4e-96 321.5 0.4 8.6e-96 321.0 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CUU99474.1 - 3.5e-10 39.8 2.3 9.8e-10 38.4 2.3 1.8 1 0 0 1 1 1 1 WW domain WW PF00397.26 CUU99475.1 - 1.4e-10 41.0 3.4 5.6e-10 39.1 3.4 2.1 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 CUU99475.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain HHV6-IE PF03753.13 CUU99476.1 - 0.17 9.3 0.1 0.2 9.1 0.1 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein CoaE PF01121.20 CUU99479.1 - 8.9e-06 25.5 0.1 1.2e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase VEGFR-2_TMD PF17988.1 CUU99479.1 - 7.9 6.0 6.5 13 5.3 6.5 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain VATC PF18716.1 CUU99481.1 - 0.24 11.3 3.2 0.35 10.8 0.6 2.0 1 1 1 2 2 2 0 Vms1-associating treble clef domain Gon7 PF08738.10 CUU99485.1 - 0.096 12.8 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Gon7 family CHCH PF06747.13 CUU99486.1 - 0.00093 19.3 2.8 0.0016 18.5 2.8 1.3 1 0 0 1 1 1 1 CHCH domain RNA_pol_Rpb4 PF03874.16 CUU99487.1 - 0.0014 19.0 1.8 0.002 18.5 1.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF3551 PF12071.8 CUU99488.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) AIG2_2 PF13772.6 CUU99490.1 - 0.13 12.6 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 AIG2-like family Sec7_N PF12783.7 CUU99492.1 - 0.023 14.6 0.3 0.026 14.4 0.3 1.0 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal YlbD_coat PF14071.6 CUU99492.1 - 0.027 14.7 0.1 0.031 14.5 0.1 1.1 1 0 0 1 1 1 0 Putative coat protein Vps54 PF07928.12 CUU99492.1 - 0.061 13.8 0.1 0.074 13.5 0.1 1.1 1 0 0 1 1 1 0 Vps54-like protein HU-CCDC81_bac_2 PF18175.1 CUU99492.1 - 0.066 13.1 1.4 1.4 8.8 0.1 2.1 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 P22_AR_N PF10547.9 CUU99492.1 - 0.07 13.5 0.1 0.081 13.3 0.1 1.3 1 0 0 1 1 1 0 P22_AR N-terminal domain DUF1002 PF06207.11 CUU99492.1 - 0.07 12.6 0.3 0.083 12.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) CSN8_PSD8_EIF3K PF10075.9 CUU99492.1 - 0.091 12.7 0.6 1.8 8.6 0.1 2.0 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Condensin2nSMC PF12422.8 CUU99492.1 - 0.11 12.7 0.0 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit YtxH PF12732.7 CUU99492.1 - 0.13 12.8 0.3 0.18 12.3 0.3 1.3 1 0 0 1 1 1 0 YtxH-like protein WES_acyltransf PF03007.16 CUU99493.1 - 0.0006 19.7 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain ANF_receptor PF01094.28 CUU99493.1 - 0.0007 18.8 0.0 0.00097 18.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2181 PF10223.9 CUU99493.1 - 0.0051 16.3 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2181) Piwi PF02171.17 CUU99494.1 - 0.048 12.9 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Piwi domain Glyco_hydro_cc PF11790.8 CUU99494.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Ras PF00071.22 CUU99496.1 - 1.3e-41 141.9 0.1 2.1e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CUU99496.1 - 4.3e-20 72.1 0.1 9.2e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CUU99496.1 - 7.2e-10 38.6 0.4 1e-09 38.1 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CUU99496.1 - 9.3e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CUU99496.1 - 0.019 14.5 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B TetR_C_16 PF17920.1 CUU99496.1 - 0.18 12.0 0.0 0.66 10.2 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 CUU99497.1 - 7.8e-42 142.6 0.1 8.9e-42 142.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CUU99497.1 - 3.2e-20 72.6 0.1 4.9e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CUU99497.1 - 3.5e-10 39.6 0.4 4.4e-10 39.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CUU99497.1 - 4.5e-05 23.1 0.0 6.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CUU99497.1 - 0.011 15.2 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B TetR_C_16 PF17920.1 CUU99497.1 - 0.082 13.2 0.0 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Gtr1_RagA PF04670.12 CUU99497.1 - 0.13 11.5 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CAP PF00188.26 CUU99498.1 - 5e-13 50.0 2.3 1.1e-11 45.7 1.0 2.5 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Aminotran_1_2 PF00155.21 CUU99499.1 - 8.2e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_11 PF08241.12 CUU99500.1 - 5.6e-13 49.3 0.0 1.5e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CUU99500.1 - 3e-10 40.2 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CUU99500.1 - 5.1e-10 39.9 0.0 1.4e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CUU99500.1 - 1.6e-08 35.2 0.0 2.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CUU99500.1 - 9.7e-06 25.4 0.0 3.1e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CUU99500.1 - 0.0044 16.4 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 CUU99500.1 - 0.0067 15.7 0.6 0.013 14.7 0.4 1.5 2 0 0 2 2 2 1 SAM dependent carboxyl methyltransferase TPR_19 PF14559.6 CUU99501.1 - 3.9e-11 43.3 6.4 1.2e-05 25.7 0.0 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CUU99501.1 - 4.8e-08 33.1 13.9 1.1e-05 25.6 1.3 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CUU99501.1 - 5.9e-08 32.7 0.4 0.0002 21.4 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CUU99501.1 - 1.6e-07 30.9 12.1 0.058 13.5 0.6 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CUU99501.1 - 1.3e-05 24.9 2.1 0.0015 18.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CUU99501.1 - 1.4e-05 25.5 2.9 2.8 9.0 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CUU99501.1 - 6.2e-05 23.4 8.8 0.023 15.3 0.1 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CUU99501.1 - 0.00038 21.0 3.9 2.1 9.0 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CUU99501.1 - 0.00071 19.6 8.6 1 9.8 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CUU99501.1 - 0.0044 17.3 8.5 0.28 11.5 0.0 5.1 5 2 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CUU99501.1 - 0.02 15.0 2.1 0.34 11.0 0.6 3.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CUU99501.1 - 0.19 11.6 0.0 0.19 11.6 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CUU99501.1 - 0.25 11.3 3.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CUU99501.1 - 0.93 9.6 5.7 28 4.9 0.2 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ERG4_ERG24 PF01222.17 CUU99502.1 - 4.7e-37 127.8 10.5 5.7e-37 127.5 10.5 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CUU99502.1 - 2.3e-05 24.0 0.1 8.6e-05 22.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CUU99502.1 - 7.9e-05 23.0 2.2 0.00024 21.5 0.0 3.0 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 CUU99502.1 - 0.046 14.1 0.0 0.21 12.0 0.0 2.2 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 CUU99502.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.2 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase zf-C4 PF00105.18 CUU99503.1 - 2e-45 153.1 32.0 3.7e-23 81.7 12.2 2.3 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CUU99503.1 - 0.025 14.1 3.6 0.12 11.9 3.6 2.0 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor C1_2 PF03107.16 CUU99503.1 - 0.044 14.1 1.2 0.044 14.1 1.2 3.6 4 0 0 4 4 4 0 C1 domain zf-RRPl_C4 PF17026.5 CUU99503.1 - 0.45 10.6 10.6 1.5 9.0 1.1 2.5 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Band_7 PF01145.25 CUU99505.1 - 8.5e-22 78.0 0.0 8.5e-22 78.0 0.0 2.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 CUU99505.1 - 9e-09 35.6 9.1 9e-09 35.6 9.1 4.3 3 2 2 5 5 5 1 Flotillin DUF702 PF05142.12 CUU99505.1 - 3.9 7.9 8.2 7.5 7.0 6.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF702) HAD_2 PF13419.6 CUU99506.1 - 6.5e-12 45.9 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CUU99506.1 - 2.2e-07 31.4 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMEM101 PF15111.6 CUU99506.1 - 6.6e-07 29.1 9.9 1.7e-06 27.8 9.9 1.6 1 1 0 1 1 1 1 TMEM101 protein family UPF0203 PF05254.12 CUU99507.1 - 0.72 10.1 5.2 1.4 9.2 0.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) PX PF00787.24 CUU99508.1 - 5.8e-15 55.3 0.1 1e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 PX domain UPF0203 PF05254.12 CUU99509.1 - 0.72 10.1 5.2 1.4 9.2 0.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) PX PF00787.24 CUU99510.1 - 2.2e-14 53.4 1.3 3.8e-14 52.6 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CUU99510.1 - 2.3e-13 50.2 6.0 7.8e-11 42.0 6.0 2.4 1 1 0 1 1 1 1 Vps5 C terminal like PA28_beta PF02252.18 CUU99511.1 - 1.1e-49 167.8 0.1 2.8e-49 166.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CUU99511.1 - 3.8e-05 23.6 0.1 0.00011 22.2 0.1 1.8 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit Ribonuclease_T2 PF00445.18 CUU99512.1 - 1.8e-41 142.4 6.2 2.2e-41 142.1 6.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF3585 PF12130.8 CUU99513.1 - 8.7e-34 116.6 10.9 2.5e-33 115.1 10.9 1.8 1 0 0 1 1 1 1 Bivalent Mical/EHBP Rab binding domain NT-C2 PF10358.9 CUU99513.1 - 1.8e-22 79.7 0.2 3.5e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins CH PF00307.31 CUU99513.1 - 1.8e-14 53.9 0.0 4.7e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CUU99513.1 - 0.00026 20.8 2.5 0.075 12.9 0.0 3.7 4 0 0 4 4 4 2 CAMSAP CH domain DUF717 PF05338.12 CUU99513.1 - 0.11 12.7 0.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Ank_4 PF13637.6 CUU99515.1 - 2.9e-05 24.5 0.0 3.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CUU99515.1 - 0.00093 19.7 0.1 0.003 18.1 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CUU99515.1 - 0.0052 17.1 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF951 PF06107.11 CUU99515.1 - 0.0052 16.7 0.0 0.0076 16.1 0.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF951) Ank_3 PF13606.6 CUU99515.1 - 0.0068 16.8 0.0 0.14 12.8 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 CUU99515.1 - 0.066 13.7 0.0 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ribosomal_L36e PF01158.18 CUU99515.1 - 0.09 13.0 0.1 0.13 12.6 0.1 1.2 1 1 0 1 1 1 0 Ribosomal protein L36e FHA PF00498.26 CUU99521.1 - 1.6e-11 44.4 0.4 2.4e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CUU99521.1 - 0.0019 18.5 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HrpE PF06188.12 CUU99522.1 - 0.064 13.1 0.9 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Pro_isomerase PF00160.21 CUU99523.1 - 2.2e-50 171.0 0.1 2.6e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Swi3 PF07962.12 CUU99524.1 - 3.7e-24 84.5 0.0 6.7e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RecQ5 PF06959.11 CUU99524.1 - 0.0096 15.9 1.0 0.019 15.0 1.0 1.4 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) PRTase_1 PF11202.8 CUU99526.1 - 0.026 13.8 0.0 0.03 13.6 0.0 1.0 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) Homeodomain PF00046.29 CUU99527.1 - 0.00012 21.9 0.9 0.00017 21.3 0.2 1.7 2 1 0 2 2 2 1 Homeodomain DUF3929 PF13066.6 CUU99528.1 - 0.13 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) RNB PF00773.19 CUU99529.1 - 3.2e-85 286.4 0.0 5.2e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CUU99529.1 - 1.4e-20 73.1 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CUU99529.1 - 2e-07 31.1 0.0 5.8e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 CUU99529.1 - 0.0026 17.5 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CUU99529.1 - 0.003 17.5 0.1 0.079 12.9 0.3 3.0 2 1 0 2 2 2 1 S1 domain Defensin_1 PF00323.19 CUU99529.1 - 0.22 12.1 1.0 0.51 10.9 1.0 1.6 1 0 0 1 1 1 0 Mammalian defensin Ribosomal_L13e PF01294.18 CUU99530.1 - 2.4e-64 216.5 4.9 4.2e-64 215.7 4.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L13e ELYS-bb PF16687.5 CUU99530.1 - 4.2e-17 61.9 2.1 1.2e-10 40.7 0.6 2.9 2 1 0 2 2 2 2 beta-propeller of ELYS nucleoporin PMI_typeI PF01238.21 CUU99531.1 - 1.7e-88 297.3 0.0 4e-87 292.8 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 CUU99531.1 - 0.019 14.6 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Cupin domain zf-C2H2 PF00096.26 CUU99533.1 - 6.3e-10 39.0 5.1 0.00013 22.2 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99533.1 - 2.9e-06 27.7 4.5 0.0012 19.5 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU99533.1 - 4e-06 27.0 7.2 0.015 15.7 4.3 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CUU99533.1 - 1.7e-05 24.6 6.4 0.017 15.1 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CUU99533.1 - 0.00023 21.4 7.2 0.0085 16.4 0.2 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 CUU99533.1 - 0.001 19.5 0.7 0.08 13.4 0.1 2.7 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-met PF12874.7 CUU99533.1 - 0.0035 17.7 2.2 1.9 9.0 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CUU99533.1 - 0.0039 17.5 4.0 0.0058 16.9 4.0 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 CUU99533.1 - 0.013 16.3 1.0 0.016 15.9 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbon family Prok-RING_1 PF14446.6 CUU99533.1 - 0.014 15.3 1.2 2.7 8.0 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 CUU99533.1 - 0.044 13.9 3.2 0.09 12.9 3.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 CUU99533.1 - 0.25 11.5 1.7 0.6 10.3 1.7 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 CUU99533.1 - 0.3 11.0 2.5 4.4 7.2 0.2 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF4460 PF14687.6 CUU99535.1 - 0.041 13.9 0.1 0.041 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) TPR_12 PF13424.6 CUU99538.1 - 1.2e-12 47.9 7.0 1.2e-07 31.8 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CUU99538.1 - 8.9e-05 23.0 1.6 9.9 7.3 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CUU99538.1 - 0.00018 21.3 0.4 12 6.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CUU99538.1 - 0.0003 20.7 2.8 12 6.3 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CUU99538.1 - 0.0072 16.8 11.4 4.5 7.9 0.1 5.0 3 2 3 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 CUU99538.1 - 0.01 15.9 1.7 0.21 11.7 0.7 3.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 CUU99538.1 - 0.019 15.6 2.0 91 4.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 CUU99538.1 - 0.45 9.7 0.0 0.45 9.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 CUU99538.1 - 1.5 8.7 6.8 0.4 10.6 0.2 3.0 4 0 0 4 4 4 0 YfdX protein HAP1_N PF04849.13 CUU99539.1 - 0.0005 19.4 3.0 0.00071 18.9 3.0 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region PI3K_P85_iSH2 PF16454.5 CUU99539.1 - 0.0024 17.5 2.1 0.0039 16.8 2.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cnn_1N PF07989.11 CUU99539.1 - 0.006 16.7 2.1 0.011 15.9 2.1 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Mod_r PF07200.13 CUU99539.1 - 0.0072 16.4 0.6 0.013 15.6 0.6 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.11 CUU99539.1 - 0.011 15.9 1.5 0.022 15.0 1.5 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Herpes_UL6 PF01763.16 CUU99539.1 - 0.015 13.8 0.5 0.023 13.3 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like PspB PF06667.12 CUU99542.1 - 0.038 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B AlphaC_C PF17480.2 CUU99542.1 - 0.076 13.0 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 AlphaC C-terminal DASH_Dam1 PF08653.10 CUU99542.1 - 0.18 11.6 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 EMP70 PF02990.16 CUU99544.1 - 1.3e-168 561.9 16.5 1.8e-168 561.5 16.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Mur_ligase_M PF08245.12 CUU99545.1 - 2.1e-08 34.4 0.0 4.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CUU99545.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF3398 PF11878.8 CUU99546.1 - 1.2e-11 45.0 0.0 1.6e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) CaKB PF03185.15 CUU99547.1 - 7.1e-07 29.1 2.0 8.1e-07 28.9 2.0 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit DUF5415 PF17436.2 CUU99548.1 - 0.0051 16.9 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5415) DUF1923 PF09083.10 CUU99548.1 - 0.094 12.4 0.1 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) RhoGEF PF00621.20 CUU99549.1 - 1.5e-11 44.8 0.4 4.2e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CUU99549.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Guanylate_cyc PF00211.20 CUU99550.1 - 4.1e-51 173.2 0.0 3.8e-47 160.3 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 CUU99550.1 - 0.009 15.5 0.7 0.013 14.9 0.7 1.3 1 0 0 1 1 1 1 Heme NO binding associated Kunitz_BPTI PF00014.23 CUU99551.1 - 5.3e-19 68.2 2.3 6.3e-19 68.0 2.3 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_M56 PF05569.11 CUU99554.1 - 0.065 12.4 0.1 0.067 12.4 0.1 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 PLAC9 PF15205.6 CUU99554.1 - 0.072 13.5 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 Placenta-specific protein 9 VASP_tetra PF08776.11 CUU99554.1 - 0.075 12.6 1.9 0.15 11.7 1.9 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain DUF730 PF05325.11 CUU99554.1 - 0.11 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF730) TB2_DP1_HVA22 PF03134.19 CUU99554.1 - 0.4 10.7 2.6 0.61 10.1 2.6 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family TMEM234 PF10639.9 CUU99555.1 - 2.9e-05 24.1 1.7 3.9e-05 23.7 1.7 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CUU99555.1 - 0.0021 18.2 1.7 0.0027 17.9 1.7 1.2 1 0 0 1 1 1 1 EamA-like transporter family LAMTOR5 PF16672.5 CUU99555.1 - 0.046 13.7 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Spem1 PF15670.5 CUU99556.1 - 0.036 13.7 2.3 0.066 12.8 2.3 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 LRR_9 PF14580.6 CUU99557.1 - 9.6e-18 64.3 5.7 2.7e-08 33.5 2.4 4.1 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 CUU99557.1 - 5.1e-12 45.8 16.4 3e-05 24.3 1.8 4.4 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CUU99557.1 - 3.5e-09 36.3 20.4 9.5e-06 25.3 8.3 3.7 1 1 1 3 3 3 3 Leucine rich repeat DUF724 PF05266.14 CUU99557.1 - 0.00048 20.0 7.5 0.00048 20.0 7.5 9.8 6 2 7 13 13 13 1 Protein of unknown function (DUF724) LPP PF04728.13 CUU99557.1 - 0.012 16.0 0.4 0.012 16.0 0.4 9.0 8 1 1 9 9 9 0 Lipoprotein leucine-zipper LRR_6 PF13516.6 CUU99557.1 - 0.19 11.9 15.8 16 5.8 1.1 5.4 4 1 1 5 5 5 0 Leucine Rich repeat Ribosomal_S10 PF00338.22 CUU99558.1 - 1.3e-16 60.6 0.0 1.7e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Nop14 PF04147.12 CUU99559.1 - 0.011 14.0 25.9 0.015 13.6 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CUU99559.1 - 0.037 13.5 30.1 0.055 12.9 30.1 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 CUU99559.1 - 0.29 9.6 26.7 0.4 9.1 26.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Raftlin PF15250.6 CUU99559.1 - 0.37 9.5 11.2 0.58 8.9 11.2 1.2 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 CUU99559.1 - 0.58 8.4 23.4 0.79 7.9 23.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 CUU99559.1 - 1.1 7.8 50.1 0.075 11.6 38.4 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 CUU99559.1 - 1.5 7.5 11.7 1.8 7.3 11.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PNISR PF15996.5 CUU99559.1 - 3 8.1 21.2 0.27 11.5 16.2 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR SpoIIIAH PF12685.7 CUU99559.1 - 4 7.2 17.7 8 6.2 17.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 CUU99559.1 - 4.3 7.1 16.4 6 6.6 16.1 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 CUU99559.1 - 4.5 7.5 25.3 8.5 6.6 25.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CCSAP PF15748.5 CUU99559.1 - 5.9 7.0 20.8 0.39 10.9 13.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated PRCC PF10253.9 CUU99559.1 - 6.9 7.4 23.2 3.4 8.4 12.5 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Vfa1 PF08432.10 CUU99559.1 - 7.1 6.9 15.3 2.1 8.7 12.1 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 CUU99559.1 - 7.7 5.2 14.0 13 4.4 14.0 1.4 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CUU99559.1 - 9.5 5.3 12.0 15 4.7 12.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.22 CUU99560.1 - 2.2e-19 69.1 0.2 1.2e-18 66.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 CUU99560.1 - 4.4e-18 64.8 34.1 1.3e-05 25.3 2.6 6.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.26 CUU99560.1 - 4.7e-16 58.3 51.7 0.00033 20.9 2.8 7.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99560.1 - 9.5e-12 44.7 49.2 0.0048 17.6 2.5 7.4 7 0 0 7 7 6 5 C2H2-type zinc finger zf-Di19 PF05605.12 CUU99560.1 - 0.013 15.8 28.9 0.028 14.7 2.3 3.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CUU99560.1 - 0.036 14.5 0.3 0.036 14.5 0.3 7.6 8 1 1 9 9 9 0 Zinc-finger of C2H2 type RRM_5 PF13893.6 CUU99560.1 - 0.047 13.3 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuc_red_2_N PF08471.10 CUU99560.1 - 0.073 13.3 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase zf-RING_7 PF02591.15 CUU99560.1 - 0.089 13.0 4.9 1.4 9.1 0.4 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_jaz PF12171.8 CUU99560.1 - 0.4 11.0 0.1 0.4 11.0 0.1 7.9 8 1 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CUU99560.1 - 1.9 8.5 7.7 31 4.6 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type EMC1_C PF07774.13 CUU99561.1 - 2e-129 429.6 0.0 8.4e-63 211.9 0.0 3.7 3 0 0 3 3 3 2 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CUU99561.1 - 2.6e-06 27.2 0.0 0.16 11.5 0.0 4.7 3 1 0 3 3 3 2 PQQ-like domain Clavanin PF05452.11 CUU99561.1 - 0.0032 17.6 0.4 48 4.2 0.0 4.9 5 0 0 5 5 5 0 Clavanin Gp_UL130 PF11668.8 CUU99561.1 - 0.078 12.9 0.0 23 4.9 0.0 2.6 2 0 0 2 2 2 0 HCMV glycoprotein pUL130 Ski_Sno PF02437.17 CUU99561.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 SKI/SNO/DAC family IlvN PF07991.12 CUU99561.1 - 0.14 11.7 0.0 24 4.4 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PMP22_Claudin PF00822.20 CUU99562.1 - 2.4e-09 37.3 1.8 5.1e-09 36.2 1.8 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family SET PF00856.28 CUU99563.1 - 1.4e-06 28.8 0.2 2.7e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 SET domain Prok-RING_4 PF14447.6 CUU99563.1 - 0.16 11.9 6.3 0.76 9.7 0.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 CUU99563.1 - 1.3 9.6 5.8 3.2 8.3 0.4 2.5 1 1 1 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2318 PF10080.9 CUU99563.1 - 1.6 8.9 4.4 4.6 7.4 2.9 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-Sec23_Sec24 PF04810.15 CUU99563.1 - 2.1 8.5 6.3 1.5 8.9 2.6 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4 PF00097.25 CUU99563.1 - 3.1 7.7 6.8 1.3 9.0 2.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SesA PF17107.5 CUU99564.1 - 0.0067 16.6 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RPW8 PF05659.11 CUU99565.1 - 0.05 13.3 0.0 0.057 13.1 0.0 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BAR PF03114.18 CUU99566.1 - 4.4e-15 56.0 8.9 5.4e-15 55.7 8.9 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 CUU99566.1 - 5.4e-07 29.4 5.7 8.4e-07 28.8 5.7 1.4 1 1 0 1 1 1 1 Arfaptin-like domain BAR_2 PF10455.9 CUU99566.1 - 2.2e-06 27.1 10.1 3.9e-06 26.2 10.1 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking LemA PF04011.12 CUU99566.1 - 0.0058 16.5 1.5 0.06 13.2 1.1 2.2 1 1 1 2 2 2 1 LemA family BAR_3 PF16746.5 CUU99566.1 - 0.015 15.0 9.2 0.033 13.9 9.1 1.7 1 1 0 1 1 1 0 BAR domain of APPL family T2SSF PF00482.23 CUU99566.1 - 0.18 11.7 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HIP1_clath_bdg PF16515.5 CUU99566.1 - 0.64 10.7 7.3 1.1 9.9 5.6 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CUU99566.1 - 0.9 9.6 8.1 0.89 9.6 4.9 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 CUU99566.1 - 1.2 9.8 7.0 1.9 9.2 1.0 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4404 PF14357.6 CUU99566.1 - 2.4 8.8 5.2 7.2 7.3 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3742 PF12553.8 CUU99567.1 - 0.049 13.8 0.9 0.077 13.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) RMI1_N PF08585.12 CUU99568.1 - 7.1e-08 32.5 0.1 4e-07 30.0 0.0 2.0 2 1 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 CUU99569.1 - 5.6e-37 126.8 0.0 4.5e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Recq-mediated genome instability protein 1, C-terminal OB-fold Phage_connect_1 PF05135.13 CUU99569.1 - 0.0044 17.5 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 2 Phage gp6-like head-tail connector protein Nup54 PF13874.6 CUU99569.1 - 0.057 13.5 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HMA PF00403.26 CUU99569.1 - 0.12 12.9 0.0 29 5.2 0.0 2.3 2 0 0 2 2 2 0 Heavy-metal-associated domain RMI1_C PF16099.5 CUU99570.1 - 5.2e-05 23.1 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Isy1 PF06246.12 CUU99572.1 - 2.8e-06 27.1 4.5 3.6e-06 26.7 4.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Radical_SAM PF04055.21 CUU99572.1 - 0.0087 16.4 0.8 0.032 14.6 0.1 1.9 1 1 1 2 2 2 1 Radical SAM superfamily IL17R_D_N PF16742.5 CUU99574.1 - 0.14 12.2 1.0 0.15 12.1 0.2 1.4 2 0 0 2 2 2 0 N-terminus of interleukin 17 receptor D DUF2897 PF11446.8 CUU99576.1 - 1.5 8.7 3.6 2.7 7.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) LRR_4 PF12799.7 CUU99577.1 - 0.0096 16.3 1.8 0.24 11.9 0.1 3.7 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) RNA_pol_3_Rpc31 PF11705.8 CUU99577.1 - 9.9 6.3 15.2 17 5.6 15.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 L51_S25_CI-B8 PF05047.16 CUU99579.1 - 5.8e-08 32.5 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Diphtheria_R PF01324.19 CUU99579.1 - 0.066 12.9 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Diphtheria toxin, R domain Ribosomal_L23 PF00276.20 CUU99580.1 - 8.1e-17 61.4 3.9 8.1e-17 61.4 3.9 3.2 3 2 0 3 3 3 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CUU99580.1 - 4.3e-15 55.6 3.0 4.3e-15 55.6 3.0 3.2 3 1 0 3 3 3 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CUU99580.1 - 0.16 11.8 3.3 0.72 9.7 0.2 2.5 2 1 0 2 2 2 0 Sulfurtransferase TusA SAM_adeno_trans PF01887.16 CUU99582.1 - 0.037 13.5 0.0 0.039 13.4 0.0 1.0 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase B56 PF01603.20 CUU99586.1 - 2.2e-17 63.2 0.0 2.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Umbravirus_LDM PF04817.12 CUU99586.1 - 0.015 14.7 6.0 0.43 9.9 1.5 2.1 1 1 1 2 2 2 0 Umbravirus long distance movement (LDM) family RRM_1 PF00076.22 CUU99587.1 - 5.7e-20 70.9 0.0 8.6e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CUU99587.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CUU99587.1 - 0.041 14.0 0.1 0.067 13.3 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 Tubulin PF00091.25 CUU99589.1 - 1.3e-127 423.6 0.0 3.5e-66 223.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CUU99589.1 - 5.9e-95 314.1 0.0 4.9e-46 156.0 0.0 2.3 2 0 0 2 2 2 2 Tubulin C-terminal domain Tubulin_3 PF14881.6 CUU99589.1 - 5.7e-08 32.7 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 Tubulin domain Tubulin_2 PF13809.6 CUU99589.1 - 0.014 14.6 0.4 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Tubulin like DUF1906 PF08924.11 CUU99589.1 - 0.023 14.8 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) MSP PF01716.18 CUU99589.1 - 0.046 12.9 0.0 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide Cdc13_OB4_dimer PF18233.1 CUU99589.1 - 0.13 12.4 0.2 29 4.8 0.0 2.5 2 0 0 2 2 2 0 Cdc13 OB4 dimerization domain DUF5610 PF18433.1 CUU99589.1 - 0.21 12.1 0.4 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) Glyco_trans_A_1 PF09318.10 CUU99591.1 - 0.027 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A zf-RING_2 PF13639.6 CUU99594.1 - 1.5e-15 57.3 30.1 2.1e-08 34.4 14.5 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CUU99594.1 - 8.9e-12 45.1 29.1 2.7e-06 27.6 5.9 3.0 1 1 1 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CUU99594.1 - 3.6e-10 39.6 29.1 2.7e-05 23.9 5.7 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CUU99594.1 - 3.2e-08 33.3 26.7 2.6e-06 27.2 11.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CUU99594.1 - 9.6e-08 31.7 31.8 0.00011 21.9 15.8 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CUU99594.1 - 3.1e-07 30.3 22.4 0.0011 19.0 4.3 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CUU99594.1 - 6.6e-06 25.6 5.7 6.6e-06 25.6 5.7 2.3 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CUU99594.1 - 4.1e-05 23.5 25.9 0.0039 17.2 8.5 3.1 3 1 1 4 4 4 2 RING-type zinc-finger zf-RING_5 PF14634.6 CUU99594.1 - 4.4e-05 23.4 30.5 0.016 15.2 7.6 2.6 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CUU99594.1 - 0.0018 18.4 2.3 0.0018 18.4 2.3 3.4 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CUU99594.1 - 0.0041 16.8 4.4 0.0041 16.8 4.4 3.0 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 CUU99594.1 - 0.0093 15.8 28.8 0.023 14.5 12.7 3.4 2 2 2 4 4 4 1 Prokaryotic RING finger family 4 L51_S25_CI-B8 PF05047.16 CUU99594.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1244 PF06844.11 CUU99594.1 - 0.6 10.3 10.4 0.1 12.8 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1244) FANCL_C PF11793.8 CUU99594.1 - 2.1 8.6 26.5 0.45 10.7 5.2 3.3 2 2 0 2 2 2 0 FANCL C-terminal domain Flu_C_NS1 PF03506.13 CUU99597.1 - 0.07 13.1 0.1 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) ACI44 PF15270.6 CUU99598.1 - 7.8e-07 29.2 16.2 0.003 17.7 3.9 2.2 2 0 0 2 2 2 2 Metallo-carboxypeptidase inhibitor Pro-rich PF15240.6 CUU99598.1 - 1.9e-06 28.3 0.0 0.076 13.3 0.0 2.1 2 0 0 2 2 2 2 Proline-rich Toxin_29 PF08116.11 CUU99598.1 - 4.1e-06 26.7 16.1 0.0075 16.2 4.1 2.3 2 0 0 2 2 2 2 PhTx neurotoxin family DUF4834 PF16118.5 CUU99598.1 - 5e-05 24.2 1.2 0.46 11.5 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) WAP PF00095.21 CUU99598.1 - 5.5e-05 23.5 18.3 0.03 14.7 5.2 2.2 2 0 0 2 2 2 2 WAP-type (Whey Acidic Protein) 'four-disulfide core' TMEM208_SND2 PF05620.11 CUU99598.1 - 7.6e-05 22.6 1.4 0.27 11.0 0.1 2.4 2 0 0 2 2 2 2 SRP-independent targeting protein 2/TMEM208 DX PF01666.17 CUU99598.1 - 0.00038 20.9 13.9 0.093 13.2 3.0 2.3 2 0 0 2 2 2 2 DX module Connexin PF00029.19 CUU99598.1 - 0.00072 19.4 3.7 0.1 12.4 0.5 2.1 1 1 1 2 2 2 2 Connexin Dickkopf_N PF04706.12 CUU99598.1 - 0.00083 19.8 16.5 0.14 12.7 4.3 2.5 2 0 0 2 2 2 2 Dickkopf N-terminal cysteine-rich region TMEM215 PF15746.5 CUU99598.1 - 0.0042 16.6 10.9 0.19 11.2 1.6 2.2 2 0 0 2 2 2 2 TMEM215 family Tombus_P19 PF03220.13 CUU99598.1 - 0.0056 16.4 1.9 1.8 8.2 0.2 2.1 2 0 0 2 2 2 2 Tombusvirus P19 core protein FtsK_4TM PF13491.6 CUU99598.1 - 0.0056 16.4 0.4 0.65 9.7 0.0 2.1 2 0 0 2 2 2 1 4TM region of DNA translocase FtsK/SpoIIIE FAM209 PF15206.6 CUU99598.1 - 0.0068 16.2 0.7 3.7 7.3 0.0 2.6 1 1 0 2 2 2 2 FAM209 family V_ATPase_I PF01496.19 CUU99598.1 - 0.0094 13.9 0.8 1 7.2 0.1 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family EB PF01683.18 CUU99598.1 - 0.012 15.8 10.8 0.6 10.4 1.9 2.3 2 0 0 2 2 2 0 EB module MMM1 PF10296.9 CUU99598.1 - 0.053 12.6 0.0 8.2 5.4 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 SafA PF17073.5 CUU99598.1 - 0.1 12.6 0.4 7.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Two-component-system connector protein Host_attach PF10116.9 CUU99598.1 - 0.33 11.5 8.8 3.8 8.1 1.0 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells OATP PF03137.20 CUU99598.1 - 0.35 9.1 2.0 1.8 6.8 0.2 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EGF PF00008.27 CUU99598.1 - 0.55 10.6 15.0 3.1 8.2 3.6 2.3 2 0 0 2 2 2 0 EGF-like domain YorP PF09629.10 CUU99598.1 - 1.1 9.5 3.0 33 4.8 0.2 2.6 2 0 0 2 2 2 0 YorP protein PIP49_C PF12260.8 CUU99598.1 - 1.3 8.7 15.7 1.6 8.3 3.5 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 CarbpepA_inh PF02977.15 CUU99598.1 - 1.7 8.5 8.9 8.2 6.3 1.3 2.2 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor VESA1_N PF12785.7 CUU99598.1 - 5.7 5.8 26.9 4.3 6.2 9.4 2.0 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 LRV_FeS PF05484.11 CUU99598.1 - 7.2 6.7 14.7 11 6.1 3.3 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Aldo_ket_red PF00248.21 CUU99599.1 - 0.00037 19.8 0.1 0.0017 17.6 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family ELM2 PF01448.24 CUU99600.1 - 2.6e-05 24.9 0.0 0.00015 22.4 0.0 2.4 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.31 CUU99600.1 - 0.0006 19.9 0.0 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_S10 PF00338.22 CUU99601.1 - 1.1e-24 86.5 0.2 1.3e-24 86.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pro_isomerase PF00160.21 CUU99603.1 - 1.3e-45 155.5 0.2 1.5e-45 155.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LOH1CR12 PF10158.9 CUU99605.1 - 4.9e-08 33.1 0.2 0.022 14.8 0.1 2.8 2 1 1 3 3 3 2 Tumour suppressor protein DUF2774 PF11242.8 CUU99605.1 - 0.00061 19.9 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2774) Cut12 PF11500.8 CUU99605.1 - 0.0016 18.4 2.1 1.3 8.9 0.2 2.3 2 0 0 2 2 2 2 Spindle pole body formation-associated protein DCA16 PF15349.6 CUU99605.1 - 0.0064 16.1 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 2 DDB1- and CUL4-associated factor 16 PilI PF10623.9 CUU99605.1 - 0.012 15.8 0.1 16 5.7 0.0 3.2 4 0 0 4 4 4 0 Plasmid conjugative transfer protein PilI PDH PF02153.17 CUU99605.1 - 0.018 14.0 0.1 5.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydrogenase CCT PF06203.14 CUU99605.1 - 0.023 14.8 2.0 7.1 6.8 0.2 2.6 2 0 0 2 2 2 0 CCT motif I_LWEQ PF01608.17 CUU99605.1 - 0.12 12.6 4.4 6.6 7.0 0.4 2.2 2 0 0 2 2 2 0 I/LWEQ domain PhoU PF01895.19 CUU99605.1 - 0.13 12.7 0.2 29 5.2 0.0 2.3 2 0 0 2 2 2 0 PhoU domain Clathrin_H_link PF13838.6 CUU99605.1 - 0.15 12.0 0.0 32 4.5 0.0 2.6 2 0 0 2 2 2 0 Clathrin-H-link DUF1833 PF08875.11 CUU99605.1 - 0.2 11.2 0.0 24 4.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1833) Flagellar_rod PF05149.12 CUU99605.1 - 0.25 10.8 2.4 12 5.3 0.2 2.1 2 0 0 2 2 2 0 Paraflagellar rod protein UPF0697 PF15117.6 CUU99605.1 - 0.25 11.4 3.1 18 5.4 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 P22_CoatProtein PF11651.8 CUU99605.1 - 0.25 9.9 0.2 13 4.2 0.0 2.2 2 1 0 2 2 2 0 P22 coat protein - gene protein 5 EAP30 PF04157.16 CUU99606.1 - 6.9e-35 120.4 2.2 1.3e-34 119.5 0.3 2.3 3 0 0 3 3 3 1 EAP30/Vps36 family Snf7 PF03357.21 CUU99606.1 - 2.6e-29 102.0 8.6 5.6e-29 100.9 2.5 2.1 2 0 0 2 2 2 2 Snf7 Vps36_ESCRT-II PF11605.8 CUU99606.1 - 1.1e-09 38.3 0.0 2.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GidB PF02527.15 CUU99606.1 - 0.026 13.9 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PH_TFIIH PF08567.11 CUU99606.1 - 0.05 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain KIAA1328 PF15369.6 CUU99607.1 - 0.011 15.6 3.8 0.012 15.4 3.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 zf-C3HC4_4 PF15227.6 CUU99611.1 - 2.8e-05 24.2 6.8 2.8e-05 24.2 6.8 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CUU99611.1 - 7.4e-05 22.7 7.4 7.4e-05 22.7 7.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 CUU99611.1 - 0.0025 17.9 4.0 0.0025 17.9 4.0 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 CUU99611.1 - 0.0046 16.8 7.8 0.0046 16.8 7.8 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CUU99611.1 - 0.0058 16.5 8.2 0.0058 16.5 8.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CUU99611.1 - 0.0072 16.2 5.6 0.0072 16.2 5.6 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 CUU99611.1 - 0.014 16.3 0.0 0.05 14.5 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 CUU99611.1 - 0.016 15.1 7.5 0.016 15.1 7.5 3.4 2 1 2 4 4 4 0 zinc-RING finger domain NOB1_Zn_bind PF08772.11 CUU99611.1 - 0.027 14.6 2.4 0.027 14.6 2.4 2.8 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_2 PF13639.6 CUU99611.1 - 0.051 13.9 7.1 0.051 13.9 7.1 2.7 2 1 0 2 2 2 0 Ring finger domain zinc_ribbon_12 PF11331.8 CUU99611.1 - 3 7.7 11.9 1 9.2 0.2 4.0 4 1 0 4 4 4 0 Probable zinc-ribbon domain Cript PF10235.9 CUU99611.1 - 8.6 7.0 12.0 0.25 11.9 4.9 2.1 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT RRM_1 PF00076.22 CUU99612.1 - 1.7e-63 210.3 3.3 1.1e-13 50.7 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CUU99612.1 - 3.1e-11 43.2 0.0 0.0092 16.0 0.0 3.5 3 0 0 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.6 CUU99612.1 - 4.3e-09 36.2 0.5 4.7 7.3 0.0 5.3 5 0 0 5 5 5 4 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CUU99612.1 - 7.4e-07 28.9 0.8 0.097 12.5 0.1 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Dodecin PF07311.12 CUU99612.1 - 0.00053 20.2 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 2 Dodecin RRM_7 PF16367.5 CUU99612.1 - 0.0014 18.7 0.2 12 6.1 0.0 4.8 5 0 0 5 5 5 1 RNA recognition motif SAVED PF18145.1 CUU99612.1 - 0.0041 17.0 0.4 3.3 7.5 0.1 2.2 2 0 0 2 2 2 2 SMODS-associated and fused to various effectors sensor domain Dynein_light PF01221.18 CUU99612.1 - 0.013 15.8 0.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Dynein light chain type 1 PHM7_cyt PF14703.6 CUU99612.1 - 0.054 13.7 0.1 5.8 7.1 0.0 3.7 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter BTB_2 PF02214.22 CUU99612.1 - 0.14 12.5 0.0 35 4.8 0.0 2.6 2 0 0 2 2 2 0 BTB/POZ domain RA PF00788.23 CUU99612.1 - 0.15 12.7 0.2 36 5.1 0.0 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain DUF3409 PF11889.8 CUU99612.1 - 0.71 9.8 3.7 39 4.3 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3409) CIA30 PF08547.12 CUU99615.1 - 7.4e-17 61.8 0.2 8.5e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Glyco_hydro_63N PF16923.5 CUU99616.1 - 1.5e-30 107.0 0.2 2.1e-30 106.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain SoPB_HTH PF18090.1 CUU99617.1 - 0.0027 17.8 0.3 1.6 8.9 0.2 2.4 2 0 0 2 2 2 2 Centromere-binding protein HTH domain DUF4125 PF13526.6 CUU99617.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) DUF498 PF04430.14 CUU99618.1 - 8.3e-22 77.3 0.0 1.1e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Acyl-CoA_dh_1 PF00441.24 CUU99619.1 - 5.9e-24 85.0 1.1 1.4e-23 83.8 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CUU99619.1 - 2.5e-18 66.8 0.0 5.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CUU99619.1 - 4.1e-17 62.2 0.0 9.9e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CUU99619.1 - 1.3e-14 54.6 0.0 2.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SoPB_HTH PF18090.1 CUU99619.1 - 0.038 14.1 0.3 7 6.9 0.2 2.5 2 0 0 2 2 2 0 Centromere-binding protein HTH domain Glyco_hydro_63 PF03200.16 CUU99620.1 - 2.2e-167 557.8 0.0 3.1e-167 557.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CUU99620.1 - 1.3e-36 126.8 0.0 2.7e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain PRP38_assoc PF12871.7 CUU99621.1 - 0.32 11.6 21.5 0.35 11.5 21.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term cwf18 PF08315.12 CUU99621.1 - 0.42 11.3 12.9 0.49 11.1 12.9 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Transformer PF06495.11 CUU99621.1 - 0.46 10.5 17.0 0.46 10.6 17.0 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Rtf2 PF04641.12 CUU99621.1 - 1.4 8.2 14.0 1.5 8.1 14.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger SWIRM-assoc_2 PF16496.5 CUU99621.1 - 7.5 5.3 14.8 7.8 5.3 14.8 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-RING_2 PF13639.6 CUU99622.1 - 7.9e-08 32.5 6.9 7.9e-08 32.5 6.9 3.2 2 0 0 2 2 2 1 Ring finger domain Filamin PF00630.19 CUU99622.1 - 1.6e-07 32.1 0.0 3.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_UBOX PF13445.6 CUU99622.1 - 1.4e-06 28.2 2.9 3.2e-06 27.1 1.2 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CUU99622.1 - 1.8e-06 27.7 5.5 1.8e-06 27.7 5.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NHL PF01436.21 CUU99622.1 - 2.6e-06 27.2 1.5 0.019 15.0 0.1 4.7 4 0 0 4 4 4 1 NHL repeat zf-RING_5 PF14634.6 CUU99622.1 - 1.3e-05 25.0 6.7 1.3e-05 25.0 6.7 3.1 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CUU99622.1 - 5.1e-05 23.1 5.1 5.1e-05 23.1 5.1 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CUU99622.1 - 7.7e-05 22.5 7.4 7.7e-05 22.5 7.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CUU99622.1 - 0.0002 21.1 4.7 0.0002 21.1 4.7 2.8 2 1 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-B_box PF00643.24 CUU99622.1 - 0.00047 20.3 3.0 0.00047 20.3 3.0 3.0 3 1 1 4 4 4 1 B-box zinc finger zf-C3HC4_2 PF13923.6 CUU99622.1 - 0.0085 15.9 7.2 0.0085 15.9 7.2 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Lebercilin PF15619.6 CUU99622.1 - 0.019 14.6 3.2 0.031 14.0 3.2 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zf-MIZ PF02891.20 CUU99622.1 - 0.061 13.1 1.9 0.21 11.4 1.9 2.0 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Invasin_D3 PF09134.10 CUU99622.1 - 0.1 12.9 0.2 0.8 10.1 0.0 2.3 2 0 0 2 2 2 0 Invasin, domain 3 zf-C3HC4_4 PF15227.6 CUU99622.1 - 3.1 8.0 16.2 0.033 14.3 5.8 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CUU99622.1 - 4.7 7.6 6.8 2.3 8.5 3.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain IBR PF01485.21 CUU99622.1 - 7.7 6.8 10.0 1.5e+02 2.7 10.0 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain HD PF01966.22 CUU99623.1 - 0.00096 19.4 0.1 0.0036 17.5 0.0 1.9 2 0 0 2 2 2 1 HD domain RNA_GG_bind PF10258.9 CUU99625.1 - 1.5e-22 79.4 0.0 2.8e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain DUF1325 PF07039.11 CUU99626.1 - 8.8e-33 113.2 0.0 1.3e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain BORCS7 PF16088.5 CUU99626.1 - 0.097 12.9 1.2 1.1 9.6 0.2 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 PDE8 PF08629.10 CUU99626.1 - 0.18 11.8 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 PDE8 phosphodiesterase Alk_phosphatase PF00245.20 CUU99627.1 - 3.2e-61 207.5 0.0 4e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Peptidase_M42 PF05343.14 CUU99627.1 - 0.14 11.1 0.0 0.31 10.0 0.0 1.5 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase PMC2NT PF08066.12 CUU99628.1 - 0.085 13.6 0.1 0.16 12.7 0.1 1.6 1 1 0 1 1 1 0 PMC2NT (NUC016) domain zf-C2H2 PF00096.26 CUU99629.1 - 2e-15 56.2 32.3 0.00096 19.5 0.2 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99629.1 - 5.7e-14 51.6 26.4 0.0027 18.4 0.2 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger CpXC PF14353.6 CUU99629.1 - 2.4e-09 37.3 5.3 0.15 12.1 0.0 5.1 2 2 1 5 5 5 2 CpXC protein zf_C2H2_ZHX PF18387.1 CUU99629.1 - 2e-07 30.5 16.3 0.017 14.8 0.0 5.4 4 2 1 5 5 5 3 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CUU99629.1 - 1.3e-06 28.5 24.8 0.028 14.7 0.6 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CUU99629.1 - 1.9e-06 27.7 29.6 0.0006 19.7 3.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf_UBZ PF18439.1 CUU99629.1 - 1.5e-05 24.5 15.1 1.7 8.3 0.1 5.4 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 CUU99629.1 - 0.0015 18.7 12.3 5 7.4 0.0 5.2 5 0 0 5 5 5 1 AN1-like Zinc finger DUF1033 PF06279.11 CUU99629.1 - 0.0025 18.0 0.1 22 5.2 0.0 3.7 3 1 1 4 4 3 0 Protein of unknown function (DUF1033) Rep_fac-A_C PF08646.10 CUU99629.1 - 0.0041 16.9 3.6 19 5.0 1.4 4.0 3 1 0 3 3 3 0 Replication factor-A C terminal domain zf-3CxxC PF13695.6 CUU99629.1 - 0.0074 16.7 4.9 35 5.0 0.1 4.7 3 1 1 4 4 4 0 Zinc-binding domain zf-H2C2_2 PF13465.6 CUU99629.1 - 0.0085 16.5 21.7 2.1 8.9 1.9 5.3 4 1 1 5 5 4 2 Zinc-finger double domain zf-met PF12874.7 CUU99629.1 - 0.0091 16.4 19.9 7.8 7.0 0.3 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CUU99629.1 - 0.053 13.6 19.1 0.57 10.3 0.1 5.1 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CUU99629.1 - 0.059 13.7 9.7 1.8 8.9 0.4 3.7 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CUU99629.1 - 0.074 13.4 0.8 0.074 13.4 0.8 3.2 3 1 1 4 4 4 0 C2H2-type zinc ribbon DUF629 PF04780.12 CUU99629.1 - 0.14 10.7 3.4 6.5 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) LIM PF00412.22 CUU99629.1 - 0.28 11.5 13.2 2.7 8.3 2.2 4.2 4 0 0 4 4 4 0 LIM domain zf-C2H2_3rep PF18868.1 CUU99629.1 - 0.42 11.3 8.1 16 6.1 0.2 4.0 2 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats PHD PF00628.29 CUU99629.1 - 0.46 10.4 15.9 4.6 7.2 0.1 4.2 4 1 0 4 4 4 0 PHD-finger zf_ZIC PF18366.1 CUU99629.1 - 0.65 10.1 14.3 30 4.8 0.3 4.9 5 0 0 5 5 5 0 Zic proteins zinc finger domain CxC3 PF18804.1 CUU99629.1 - 0.68 9.8 2.5 5.9 6.8 0.1 3.3 4 0 0 4 4 4 0 CxC3 like cysteine cluster associated with KDZ transposases FOXP-CC PF16159.5 CUU99629.1 - 1.5 9.5 12.4 6.7 7.4 0.1 4.1 5 0 0 5 5 3 0 FOXP coiled-coil domain XPA_N PF01286.18 CUU99629.1 - 1.5 8.9 20.5 17 5.6 0.5 5.1 5 0 0 5 5 5 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 CUU99629.1 - 3.5 7.5 6.0 1.7 8.5 0.3 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type HNH_5 PF14279.6 CUU99629.1 - 3.7 7.5 11.8 12 5.9 0.1 4.4 4 1 1 5 5 5 0 HNH endonuclease HalOD2 PF18547.1 CUU99629.1 - 9.9 6.2 9.5 23 5.0 0.4 3.8 4 1 1 5 5 4 0 Halobacterial output domain 2 zf-AN1 PF01428.16 CUU99631.1 - 6.3e-09 35.9 8.0 9.4e-09 35.3 8.0 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Laminin_G_2 PF02210.24 CUU99632.1 - 3.8e-66 221.4 3.6 3e-16 60.2 0.0 6.9 7 0 0 7 7 7 6 Laminin G domain Laminin_G_1 PF00054.23 CUU99632.1 - 5.9e-50 168.9 0.0 3.1e-16 59.8 0.0 6.5 6 0 0 6 6 6 6 Laminin G domain EGF PF00008.27 CUU99632.1 - 1.7e-27 95.4 328.6 0.00084 19.6 7.3 20.3 20 0 0 20 20 20 19 EGF-like domain EGF_2 PF07974.13 CUU99632.1 - 6e-14 52.1 363.0 0.052 13.9 9.1 20.7 20 0 0 20 20 20 16 EGF-like domain WD40 PF00400.32 CUU99632.1 - 1.6e-13 50.9 4.2 4.8e-08 33.5 0.3 4.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 CUU99632.1 - 0.027 13.1 1.0 0.22 10.1 0.0 2.8 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Cation_ATPase_C PF00689.21 CUU99633.1 - 2.7e-42 144.5 0.4 2.7e-42 144.5 0.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CUU99633.1 - 3.6e-23 81.4 0.0 7.8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CUU99633.1 - 8.2e-22 77.6 1.0 8.2e-22 77.6 1.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CUU99633.1 - 5e-19 69.4 0.1 8.7e-16 58.8 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CUU99633.1 - 4.1e-06 26.7 1.3 0.0018 18.1 0.8 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CUU99633.1 - 0.047 14.1 0.0 0.59 10.5 0.0 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C2H2_2 PF12756.7 CUU99634.1 - 0.025 14.9 13.5 33 4.9 0.6 6.9 7 1 0 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CUU99634.1 - 0.034 14.6 0.8 0.034 14.6 0.8 10.9 11 0 0 11 11 11 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CUU99634.1 - 0.054 13.8 0.5 0.054 13.8 0.5 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CUU99634.1 - 0.25 11.8 4.4 0.29 11.6 0.6 3.2 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DBD_HTH PF18430.1 CUU99636.1 - 1 9.2 5.0 11 5.9 0.1 3.0 3 0 0 3 3 3 0 Putative DNA-binding domain DUF2732 PF10809.8 CUU99637.1 - 0.097 12.6 1.3 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) PGA2 PF07543.12 CUU99637.1 - 1.3 9.0 4.8 31 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 SYCP2_SLD PF18584.1 CUU99639.1 - 4.4e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Synaptonemal complex 2 Spt16M-like domain MAD PF05557.13 CUU99642.1 - 3.4e-25 88.5 98.6 4.5e-22 78.2 48.5 3.0 2 2 0 2 2 2 2 Mitotic checkpoint protein DUF2935 PF11155.8 CUU99642.1 - 0.00077 19.8 7.2 8.1 6.8 0.1 6.3 5 2 0 5 5 5 2 Domain of unknown function (DUF2935) TPALS PF18178.1 CUU99642.1 - 0.0096 15.4 7.8 1.3 8.4 0.3 4.0 3 0 0 3 3 3 2 TIR- and PNP-associating SLOG family YycI PF09648.10 CUU99642.1 - 0.012 15.2 15.0 0.6 9.7 3.6 3.0 2 0 0 2 2 2 0 YycH protein DUF2536 PF10750.9 CUU99642.1 - 0.014 15.3 4.3 4.1 7.4 0.3 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Sigma70_r1_1 PF03979.14 CUU99642.1 - 0.022 14.8 5.2 4.3 7.5 0.5 3.6 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF1574 PF07611.11 CUU99642.1 - 0.046 13.0 0.6 12 5.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) ATS3 PF06232.11 CUU99642.1 - 0.064 13.2 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) Laminin_B PF00052.18 CUU99642.1 - 0.082 12.8 9.1 3.9 7.4 1.3 3.6 2 0 0 2 2 2 0 Laminin B (Domain IV) ABC_tran PF00005.27 CUU99642.1 - 0.5 10.9 5.8 25 5.4 0.6 3.9 2 0 0 2 2 2 0 ABC transporter TetR PF13972.6 CUU99642.1 - 0.51 10.0 10.5 3.4 7.4 0.3 3.8 3 0 0 3 3 3 0 Bacterial transcriptional repressor Imm3 PF14425.6 CUU99642.1 - 2.5 8.2 15.3 0.066 13.3 1.0 4.1 4 0 0 4 4 4 0 Immunity protein Imm3 CNOT1_CAF1_bind PF16415.5 CUU99643.1 - 4.5e-08 32.8 0.1 5.9e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain BcrAD_BadFG PF01869.20 CUU99643.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family LapA_dom PF06305.11 CUU99645.1 - 0.0019 18.0 0.3 0.0026 17.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain SieB PF14163.6 CUU99645.1 - 0.019 14.5 0.6 0.028 13.9 0.6 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Peptidase_M56 PF05569.11 CUU99645.1 - 0.031 13.5 0.1 0.034 13.3 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 tRNA-synt_2d PF01409.20 CUU99646.1 - 4.5e-86 288.3 0.0 5.9e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 CUU99646.1 - 2.4e-06 27.2 0.0 2.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 CUU99646.1 - 0.00013 21.9 3.2 0.0004 20.3 3.2 1.9 1 1 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 CUU99646.1 - 0.00038 19.6 0.1 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PheRS_DBD3 PF18553.1 CUU99646.1 - 0.0047 17.2 2.7 0.0065 16.7 0.7 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2b PF00587.25 CUU99646.1 - 0.067 13.1 0.0 0.48 10.4 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Apt1 PF10351.9 CUU99648.1 - 6.5e-81 272.6 3.2 3.8e-67 227.2 0.0 3.2 4 0 0 4 4 4 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CUU99648.1 - 2.9e-16 59.9 0.0 6.8e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CUU99648.1 - 1.3e-11 44.7 2.3 1.4e-11 44.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_WPPW PF10359.9 CUU99648.1 - 3.4e-07 29.5 0.4 7e-07 28.5 0.4 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CRAL_TRIO PF00650.20 CUU99650.1 - 7.3e-26 90.8 0.4 4.5e-25 88.2 0.1 2.1 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CUU99650.1 - 3.1e-05 24.1 0.9 0.00012 22.1 0.9 2.1 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CUU99650.1 - 4.8e-05 23.5 0.2 0.00022 21.4 0.0 2.1 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain HTH_16 PF12645.7 CUU99650.1 - 0.015 15.4 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain CagZ PF09053.10 CUU99650.1 - 0.016 14.8 0.3 2.3 7.8 0.1 2.4 1 1 1 2 2 2 0 CagZ RILP PF11461.8 CUU99650.1 - 0.042 14.1 0.0 5.5 7.3 0.0 2.5 1 1 1 2 2 2 0 Rab interacting lysosomal protein DUF4093 PF13331.6 CUU99650.1 - 0.061 13.8 0.0 2.3 8.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4093) FliG_N PF14842.6 CUU99650.1 - 0.063 13.8 0.0 18 5.9 0.0 2.6 1 1 1 2 2 2 0 FliG N-terminal domain BK_channel_a PF03493.18 CUU99651.1 - 1.1e-29 102.5 0.2 3e-15 56.2 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CUU99651.1 - 3.3e-20 72.4 9.6 5.8e-20 71.6 9.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CUU99651.1 - 1.7e-16 59.9 4.6 3.6e-16 58.9 3.3 2.2 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CUU99651.1 - 0.025 14.4 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel TssN PF17555.2 CUU99652.1 - 0.0022 17.4 1.3 0.0025 17.3 1.3 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssN AA_permease_2 PF13520.6 CUU99652.1 - 0.0025 16.7 1.7 0.0029 16.5 1.7 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM132D_C PF15706.5 CUU99652.1 - 0.0037 17.0 0.4 0.0054 16.5 0.1 1.4 1 1 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phage_holin_3_6 PF07332.11 CUU99652.1 - 0.0046 17.0 1.3 0.0061 16.6 1.3 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4220 PF13968.6 CUU99652.1 - 0.021 14.2 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4231 PF14015.6 CUU99652.1 - 0.023 15.2 1.0 0.028 14.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) TMEM154 PF15102.6 CUU99652.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.7 1 1 1 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 CUU99652.1 - 0.031 13.1 0.3 0.035 12.9 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_LMP1 PF05297.11 CUU99652.1 - 0.074 12.2 4.3 0.11 11.7 4.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EphA2_TM PF14575.6 CUU99652.1 - 0.18 12.7 1.0 1.4 9.9 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YMF19 PF02326.15 CUU99652.1 - 0.2 12.5 0.2 0.2 12.5 0.2 1.9 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF3043 PF11241.8 CUU99652.1 - 0.21 11.6 0.9 0.27 11.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TraP PF07296.11 CUU99652.1 - 0.21 10.7 2.3 1.9 7.6 0.4 2.0 1 1 1 2 2 2 0 TraP protein TMEM52 PF14979.6 CUU99652.1 - 0.22 11.4 0.1 0.22 11.4 0.1 1.9 1 1 1 2 2 2 0 Transmembrane 52 DUF983 PF06170.12 CUU99652.1 - 0.27 11.7 4.8 0.34 11.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF4191 PF13829.6 CUU99652.1 - 0.52 9.6 2.6 0.58 9.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SIT PF15330.6 CUU99652.1 - 0.56 10.7 3.9 0.81 10.2 0.0 2.0 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT AC_N PF16214.5 CUU99652.1 - 4.9 6.2 5.5 6 5.9 5.5 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region ECSCR PF15820.5 CUU99652.1 - 6.1 6.7 8.1 0.33 10.8 0.4 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator S-antigen PF05756.11 CUU99656.1 - 0.05 14.0 0.2 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 S-antigen protein Abhydro_lipase PF04083.16 CUU99660.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Tugs PF17840.1 CUU99664.1 - 0.1 12.8 0.1 22 5.3 0.0 2.3 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain UN_NPL4 PF11543.8 CUU99665.1 - 3.3e-05 24.3 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Death PF00531.22 CUU99666.1 - 0.00025 21.2 0.1 0.0005 20.2 0.1 1.4 1 0 0 1 1 1 1 Death domain Mt_ATP-synt_B PF05405.14 CUU99666.1 - 0.038 13.6 0.8 0.038 13.6 0.8 1.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Glyco_transf_7N PF13733.6 CUU99667.1 - 0.1 12.2 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Na_K-ATPase PF00287.18 CUU99668.1 - 8.4e-19 67.8 1.8 1e-18 67.5 1.8 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain LisH PF08513.11 CUU99669.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 LisH DUF2624 PF11116.8 CUU99669.1 - 0.026 15.4 0.9 0.07 14.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Fra10Ac1 PF09725.9 CUU99670.1 - 3.8e-46 156.2 3.6 6.4e-46 155.5 3.6 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 YbfN PF13982.6 CUU99670.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 YbfN-like lipoprotein Fra10Ac1 PF09725.9 CUU99671.1 - 1.1e-45 154.7 3.6 1.8e-45 154.0 3.6 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 CRC_subunit PF08624.10 CUU99671.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit YbfN PF13982.6 CUU99671.1 - 0.045 14.0 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 YbfN-like lipoprotein SNF5 PF04855.12 CUU99672.1 - 1.8e-58 198.1 0.2 1.2e-31 110.4 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 CRC_subunit PF08624.10 CUU99672.1 - 0.0017 18.8 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GTP_EFTU PF00009.27 CUU99674.1 - 3.4e-21 75.7 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CUU99674.1 - 7.4e-06 26.3 0.0 3.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CUU99674.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SCIMP PF15050.6 CUU99675.1 - 1.1 9.8 3.1 4.5 7.7 0.1 2.5 2 0 0 2 2 2 0 SCIMP protein Malic_M PF03949.15 CUU99676.1 - 1.1e-10 41.3 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain DUF4704 PF15787.5 CUU99676.1 - 0.054 12.7 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) MFS_1 PF07690.16 CUU99677.1 - 0.008 15.1 3.6 0.009 15.0 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CRIC_ras_sig PF10534.9 CUU99681.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Ribosomal_L30 PF00327.20 CUU99682.1 - 8.5e-20 70.4 5.8 1.4e-19 69.7 0.8 2.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CUU99682.1 - 9.4e-07 29.0 11.2 9.4e-07 29.0 11.2 2.0 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain DUF733 PF05306.11 CUU99683.1 - 0.017 15.5 0.5 0.025 14.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF733) SWIRM-assoc_1 PF16495.5 CUU99684.1 - 9.4e-30 102.4 14.2 9.4e-30 102.4 14.2 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 AOX PF01786.17 CUU99684.1 - 0.052 13.1 0.4 0.069 12.7 0.4 1.2 1 0 0 1 1 1 0 Alternative oxidase NUSAP PF16006.5 CUU99684.1 - 0.45 10.2 10.5 0.016 15.0 2.5 2.0 1 1 1 2 2 2 0 Nucleolar and spindle-associated protein IPK PF03770.16 CUU99686.1 - 6.8e-18 65.2 0.0 8.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Exo_endo_phos_2 PF14529.6 CUU99687.1 - 3.4e-10 39.8 0.1 1.4e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CUU99687.1 - 2.7e-05 23.8 0.0 0.00016 21.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ubiquitin PF00240.23 CUU99689.1 - 3.6e-11 42.6 0.2 3.5e-09 36.3 0.0 3.0 2 1 1 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.8 CUU99689.1 - 4.3e-06 26.5 0.0 1.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CUU99689.1 - 0.0062 16.5 0.3 0.49 10.5 0.0 2.7 2 1 1 3 3 3 1 Ubiquitin-like domain DUF2407 PF10302.9 CUU99689.1 - 0.054 14.1 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBX PF00789.20 CUU99689.1 - 0.086 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 UBX domain Tafi-CsgC PF10610.9 CUU99689.1 - 0.19 11.9 0.4 0.39 10.9 0.1 1.6 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein Lactamase_B PF00753.27 CUU99693.1 - 1.5e-07 31.6 2.5 1.8e-06 28.1 2.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CUU99693.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Endosulfine PF04667.17 CUU99695.1 - 0.007 16.5 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Golgin_A5 PF09787.9 CUU99695.1 - 0.031 13.7 6.5 0.044 13.2 6.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0449 PF15136.6 CUU99695.1 - 0.092 13.2 3.3 0.18 12.3 3.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Cyclin_N PF00134.23 CUU99696.1 - 4.2e-13 49.2 0.2 9.3e-13 48.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CUU99696.1 - 1.6e-07 31.4 0.2 4.2e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Methyltransf_15 PF09445.10 CUU99697.1 - 5.2e-23 81.4 0.0 7.5e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CUU99697.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SYCE1 PF15233.6 CUU99700.1 - 0.015 15.4 1.0 0.015 15.4 1.0 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 ArAE_1_C PF11728.8 CUU99700.1 - 0.05 13.6 5.0 0.24 11.4 5.0 2.0 1 1 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Exonuc_VII_L PF02601.15 CUU99700.1 - 0.27 10.8 1.5 0.48 9.9 1.6 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DMPK_coil PF08826.10 CUU99700.1 - 0.44 10.7 5.7 0.15 12.2 1.3 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Rootletin PF15035.6 CUU99700.1 - 2.4 8.1 8.7 0.41 10.7 2.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4514 PF14986.6 CUU99701.1 - 0.16 12.0 0.4 0.28 11.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) FixS PF03597.15 CUU99701.1 - 0.19 11.5 2.6 0.3 10.8 2.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Adeno_E3_CR2 PF02439.15 CUU99701.1 - 0.29 10.9 2.2 0.57 10.0 2.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cytomega_UL84 PF06284.11 CUU99702.1 - 0.47 8.9 2.4 0.47 8.9 2.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Sec62 PF03839.16 CUU99702.1 - 5 6.6 7.3 5.7 6.4 7.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 SCAPER_N PF16501.5 CUU99705.1 - 3.8e-23 81.3 0.2 9.5e-23 80.1 0.2 1.6 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum UBA2_C PF16195.5 CUU99705.1 - 0.53 11.0 6.9 0.074 13.7 2.5 1.9 2 1 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF4542 PF15075.6 CUU99706.1 - 0.016 15.6 0.4 0.058 13.8 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) Fas_alpha_ACP PF18325.1 CUU99706.1 - 0.027 14.8 0.0 0.057 13.8 0.0 1.6 2 0 0 2 2 2 0 Fatty acid synthase subunit alpha Acyl carrier domain Microtub_bind PF13931.6 CUU99706.1 - 0.054 13.9 4.6 0.037 14.4 2.0 1.9 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding DUF2207 PF09972.9 CUU99707.1 - 1.8 7.2 3.7 2 7.1 3.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP1G1_PLM_MAT8 PF02038.16 CUU99707.1 - 2.8 7.5 6.5 2.6 7.5 0.6 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family GpcrRhopsn4 PF10192.9 CUU99709.1 - 3e-23 82.5 0.8 3e-23 82.5 0.8 2.4 2 1 1 3 3 3 2 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 CUU99709.1 - 0.0063 15.8 3.4 0.0063 15.8 3.4 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2160 PF09928.9 CUU99714.1 - 0.064 13.6 0.2 0.074 13.4 0.2 1.1 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) DUF1907 PF08925.11 CUU99717.1 - 0.0007 19.1 0.0 0.00075 19.0 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) PH PF00169.29 CUU99718.1 - 2.6e-10 40.7 0.1 5.4e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 PH domain EzrA PF06160.12 CUU99718.1 - 0.0087 14.3 2.8 0.01 14.0 2.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PH_13 PF16652.5 CUU99718.1 - 0.035 13.9 0.1 0.063 13.1 0.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain FliT PF05400.13 CUU99718.1 - 0.29 12.0 5.4 0.08 13.8 2.5 1.6 2 0 0 2 2 2 0 Flagellar protein FliT PDZ PF00595.24 CUU99719.1 - 4.2e-21 75.1 0.2 3.7e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CUU99719.1 - 4.9e-17 61.5 2.2 6.2e-10 38.8 0.5 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CUU99719.1 - 1.4e-10 41.3 0.2 9.4e-05 22.7 0.1 2.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 CUU99719.1 - 0.077 13.0 0.1 9.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain Par3_HAL_N_term PF12053.8 CUU99720.1 - 5.6e-22 77.7 2.5 1.3e-10 41.4 0.0 3.3 4 0 0 4 4 4 2 N-terminal of Par3 and HAL proteins DUF2079 PF09852.9 CUU99724.1 - 0.051 12.4 0.0 0.058 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Adipogenin PF15202.6 CUU99724.1 - 0.33 11.0 2.6 7 6.8 2.4 2.1 1 1 0 2 2 2 0 Adipogenin 7TMR-DISM_7TM PF07695.11 CUU99725.1 - 0.021 14.7 3.9 0.023 14.6 3.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Claudin_2 PF13903.6 CUU99726.1 - 0.26 11.0 1.6 0.33 10.7 1.6 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspanin PF00335.20 CUU99726.1 - 0.32 10.7 3.4 0.49 10.1 3.4 1.2 1 0 0 1 1 1 0 Tetraspanin family BASP1 PF05466.12 CUU99727.1 - 0.84 9.6 9.1 1.3 9.0 9.1 1.3 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Macoilin PF09726.9 CUU99727.1 - 3 6.3 6.7 3.4 6.1 6.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF3195 PF11424.8 CUU99730.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Sdh_cyt PF01127.22 CUU99733.1 - 0.077 13.0 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HTH_1 PF00126.27 CUU99735.1 - 0.069 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_1 PF00126.27 CUU99736.1 - 0.078 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Atg8 PF02991.16 CUU99738.1 - 3.6e-42 142.8 0.0 6.1e-42 142.0 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pyr_redox_2 PF07992.14 CUU99738.1 - 2.3e-10 40.2 0.0 2.6e-06 26.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase APG12 PF04110.13 CUU99738.1 - 3.7e-06 27.3 0.0 6.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Lycopene_cycl PF05834.12 CUU99738.1 - 0.036 13.1 0.2 0.064 12.3 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CUU99738.1 - 0.045 13.7 0.1 5.3 7.0 0.0 2.6 1 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CUU99738.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Radial_spoke_3 PF06098.11 CUU99739.1 - 1.5e-75 254.2 5.1 1.5e-75 254.2 5.1 1.8 2 0 0 2 2 2 1 Radial spoke protein 3 DUF572 PF04502.13 CUU99740.1 - 2.2e-53 182.0 7.5 2.5e-53 181.8 7.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Abi_2 PF07751.11 CUU99740.1 - 0.095 13.0 0.3 0.14 12.4 0.3 1.3 1 0 0 1 1 1 0 Abi-like protein Mut7-C PF01927.16 CUU99740.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Mut7-C RNAse domain CBP4 PF07960.11 CUU99740.1 - 2.6 7.9 9.8 0.25 11.2 0.8 2.5 1 1 1 2 2 2 0 CBP4 Radial_spoke_3 PF06098.11 CUU99741.1 - 2.7e-45 154.9 3.2 2.9e-45 154.8 3.2 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 DUF572 PF04502.13 CUU99742.1 - 3.4e-57 194.6 4.4 4.1e-57 194.3 4.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Mut7-C PF01927.16 CUU99742.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.0 2 0 0 2 2 2 0 Mut7-C RNAse domain CBP4 PF07960.11 CUU99742.1 - 8.3 6.3 10.3 0.44 10.4 1.0 2.4 1 1 0 2 2 2 0 CBP4 Exo_endo_phos_2 PF14529.6 CUU99745.1 - 8.1e-08 32.1 0.1 1.5e-06 28.1 0.0 2.0 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Sec7 PF01369.20 CUU99748.1 - 1.8e-39 135.3 0.9 2.6e-39 134.8 0.9 1.2 1 0 0 1 1 1 1 Sec7 domain SUIM_assoc PF16619.5 CUU99748.1 - 0.25 11.4 5.3 0.63 10.1 1.3 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PH_9 PF15410.6 CUU99749.1 - 1.6e-35 122.0 2.3 5.7e-21 75.1 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 CUU99749.1 - 2.4e-06 28.0 0.0 0.00028 21.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PHD_3 PF13922.6 CUU99749.1 - 0.19 12.2 2.5 0.67 10.4 2.5 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Actin PF00022.19 CUU99750.1 - 0.036 12.7 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Actin DUF1935 PF09149.10 CUU99751.1 - 0.089 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) OpcA PF07239.11 CUU99753.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein OpcA NFACT-R_1 PF05670.13 CUU99753.1 - 0.12 13.0 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain PHD PF00628.29 CUU99755.1 - 5e-09 35.9 5.1 1.2e-08 34.7 5.1 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CUU99755.1 - 4.1e-06 27.3 0.5 2.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 SET domain PHD_2 PF13831.6 CUU99755.1 - 0.0086 15.6 1.2 0.022 14.3 1.2 1.7 1 0 0 1 1 1 1 PHD-finger IPK PF03770.16 CUU99756.1 - 3.7e-36 124.8 0.0 7.4e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase eIF3m_C_helix PF18005.1 CUU99756.1 - 6.2 6.6 5.7 1.8 8.3 0.4 2.6 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix WD40 PF00400.32 CUU99758.1 - 2.5e-38 129.4 19.6 6.5e-06 26.8 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CUU99758.1 - 9.1e-15 54.7 2.6 0.007 16.6 0.0 5.5 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CUU99758.1 - 4.3e-11 43.1 2.8 9.8e-05 22.3 0.4 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Tox-HDC PF15656.6 CUU99758.1 - 0.14 12.3 0.1 0.48 10.6 0.1 1.8 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature RPN1_RPN2_N PF17781.1 CUU99759.1 - 6.9e-115 383.7 1.5 1.1e-114 383.0 1.5 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CUU99759.1 - 5.9e-31 106.3 0.2 1.5e-30 105.0 0.2 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CUU99759.1 - 9.5e-19 66.8 24.7 8.2e-05 22.9 0.1 8.9 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CUU99759.1 - 0.012 16.0 4.1 2 8.9 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats DUF1635 PF07795.11 CUU99759.1 - 0.014 15.3 1.2 0.033 14.1 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RPN2_C PF18004.1 CUU99759.1 - 0.23 11.4 4.2 1.8 8.5 3.4 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hat1_N PF10394.9 CUU99760.1 - 2.2e-34 119.0 2.8 2.7e-34 118.7 1.2 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 CUU99760.1 - 0.00086 19.0 0.2 0.0015 18.2 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family FbpA PF05833.11 CUU99760.1 - 0.0084 14.9 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Acetyltransf_1 PF00583.25 CUU99760.1 - 0.025 14.8 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AC_N PF16214.5 CUU99763.1 - 7.3e-14 51.7 9.2 7.3e-14 51.7 9.2 1.3 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region Nop53 PF07767.11 CUU99763.1 - 0.0025 17.3 4.1 0.0032 16.9 4.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3510 PF12022.8 CUU99763.1 - 0.42 11.0 0.1 0.42 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF2070 PF09843.9 CUU99763.1 - 0.45 8.7 10.6 0.59 8.4 10.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3487 PF11990.8 CUU99763.1 - 3.2 7.7 16.4 2.3 8.1 6.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3487) NEMP PF10225.9 CUU99763.1 - 9.6 5.8 20.1 23 4.5 20.1 1.7 1 1 0 1 1 1 0 NEMP family NDUF_B12 PF08122.12 CUU99764.1 - 3.5e-08 33.4 5.1 1.1e-07 31.8 1.9 2.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF4132 PF13569.6 CUU99764.1 - 0.012 15.4 0.3 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4132) DUF656 PF04920.12 CUU99764.1 - 0.078 12.9 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF656) Polysacc_synt_4 PF04669.13 CUU99764.1 - 0.12 11.9 0.0 5.7 6.4 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis MarR_2 PF12802.7 CUU99764.1 - 0.17 11.8 0.1 28 4.7 0.0 2.4 2 0 0 2 2 2 0 MarR family NAF PF03822.14 CUU99765.1 - 0.15 12.3 0.1 0.36 11.0 0.1 1.6 2 0 0 2 2 2 0 NAF domain NAGLU_N PF12971.7 CUU99766.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF2418 PF10332.9 CUU99767.1 - 0.057 14.0 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Clenterotox PF03505.14 CUU99769.1 - 0.15 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin zf-LITAF-like PF10601.9 CUU99770.1 - 7.7e-23 80.6 19.0 1e-22 80.1 19.0 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 CUU99770.1 - 0.017 14.7 3.1 0.59 9.8 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CUU99770.1 - 0.04 14.2 0.8 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sgf11 PF08209.11 CUU99770.1 - 0.83 9.3 0.1 0.83 9.3 0.1 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) YacG PF03884.14 CUU99770.1 - 2.3 8.0 14.9 5.4 6.8 0.4 3.4 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-LITAF-like PF10601.9 CUU99771.1 - 6.2e-23 80.8 13.3 7.6e-23 80.6 13.3 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.9 CUU99772.1 - 8.6e-19 67.6 17.2 1.4e-18 66.9 17.2 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.9 CUU99773.1 - 2.1e-21 76.0 11.5 2.5e-21 75.7 11.5 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 CUU99773.1 - 0.015 14.9 1.8 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Cys_rich_KTR PF14205.6 CUU99773.1 - 0.077 12.8 0.1 0.077 12.8 0.1 2.9 3 1 0 3 3 3 0 Cysteine-rich KTR zinc_ribbon_2 PF13240.6 CUU99773.1 - 0.14 11.9 8.7 0.6 9.9 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 CUU99773.1 - 0.16 12.2 5.4 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon YacG PF03884.14 CUU99773.1 - 0.93 9.3 13.5 7 6.5 0.2 3.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Lambda_tail_I PF06805.12 CUU99774.1 - 0.18 12.2 0.0 0.57 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Pkinase PF00069.25 CUU99777.1 - 3.9e-41 141.1 0.1 2.4e-26 92.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99777.1 - 8.4e-05 22.0 0.0 0.033 13.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CUU99777.1 - 0.00012 22.1 0.1 0.017 15.1 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4116 PF13475.6 CUU99777.1 - 0.58 9.9 2.3 12 5.7 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) Pkinase PF00069.25 CUU99778.1 - 3.8e-17 62.5 0.0 1.9e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99778.1 - 6e-14 51.9 0.0 2.1e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CUU99778.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SLC35F PF06027.12 CUU99779.1 - 3.2e-70 237.0 16.5 4e-70 236.7 16.5 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CUU99779.1 - 5.1e-08 32.3 3.3 5.1e-08 32.3 3.3 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CUU99779.1 - 5.6e-08 33.0 23.8 2.4e-05 24.5 9.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CUU99779.1 - 3.3e-06 26.5 16.0 4.7e-06 26.0 16.0 1.1 1 0 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.14 CUU99779.1 - 8.9e-05 21.7 4.2 0.00018 20.7 4.2 1.6 1 1 0 1 1 1 1 Magnesium transporter NIPA Peptidase_S8 PF00082.22 CUU99780.1 - 2.1e-36 125.7 0.1 2.7e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Subtilase family Babuvirus_MP PF07234.11 CUU99781.1 - 0.021 15.0 0.3 0.025 14.7 0.3 1.2 1 0 0 1 1 1 0 Movement and RNA silencing protein Aim21 PF11489.8 CUU99782.1 - 0.033 13.1 1.4 0.036 13.0 1.4 1.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Chromo_shadow PF01393.19 CUU99783.1 - 4.8e-26 90.6 0.4 3.6e-22 78.2 0.0 2.3 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CUU99783.1 - 4.1e-21 74.6 1.6 2e-16 59.6 0.3 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1918 PF08940.11 CUU99783.1 - 0.013 15.1 0.0 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Mtf2_C PF14061.6 CUU99783.1 - 0.095 12.9 0.0 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Pkinase PF00069.25 CUU99784.1 - 5.3e-13 48.9 0.3 7.7e-06 25.5 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99784.1 - 1.9e-10 40.4 0.9 3.4e-05 23.3 0.1 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CUU99784.1 - 1.7e-08 34.2 0.0 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PBP_like_2 PF12849.7 CUU99784.1 - 0.00032 20.5 0.0 0.00066 19.4 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain Guanylate_cyc PF00211.20 CUU99785.1 - 2.1e-13 50.3 0.0 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MSP1b PF03429.13 CUU99785.1 - 0.012 13.8 0.2 0.62 8.1 0.1 2.0 2 0 0 2 2 2 0 Major surface protein 1B TCL1_MTCP1 PF01840.17 CUU99786.1 - 0.084 12.5 0.1 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 TCL1/MTCP1 family DUF4357 PF14267.6 CUU99786.1 - 0.098 12.6 0.1 0.098 12.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4357) SR-25 PF10500.9 CUU99786.1 - 6.9 6.2 18.2 9.1 5.8 18.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PH PF00169.29 CUU99787.1 - 6.5e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CUU99787.1 - 0.0093 16.2 0.7 0.055 13.8 0.7 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4357 PF14267.6 CUU99787.1 - 0.088 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Forkhead PF00250.18 CUU99789.1 - 5.9e-06 26.5 1.3 8.3e-06 26.0 1.3 1.2 1 0 0 1 1 1 1 Forkhead domain CopG_antitoxin PF12441.8 CUU99789.1 - 0.00077 19.9 0.1 0.0017 18.8 0.1 1.6 2 0 0 2 2 2 1 CopG antitoxin of type II toxin-antitoxin system ANTAR PF03861.14 CUU99794.1 - 0.045 13.6 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 ANTAR domain DSS1_SEM1 PF05160.13 CUU99795.1 - 7.9e-20 70.7 6.0 9.7e-20 70.4 6.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family PWWP PF00855.17 CUU99796.1 - 3.6e-05 24.1 1.0 9.2e-05 22.8 1.0 1.7 1 0 0 1 1 1 1 PWWP domain Cyclin_C_2 PF16899.5 CUU99798.1 - 5.3e-14 52.5 0.1 5.1e-11 42.9 0.0 2.6 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CUU99798.1 - 0.00096 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Proteasome PF00227.26 CUU99799.1 - 2.3e-49 167.5 0.0 2.7e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MCM PF00493.23 CUU99801.1 - 9.9e-10 37.9 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain COX5A PF02284.16 CUU99801.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va PARP PF00644.20 CUU99803.1 - 2.9e-18 66.1 0.2 1.9e-10 40.7 0.0 2.8 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CUU99803.1 - 1.3e-06 28.6 0.1 2.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain CRA PF06589.11 CUU99803.1 - 0.012 15.7 0.6 0.041 14.0 0.1 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Beach PF02138.18 CUU99805.1 - 6.1e-50 170.1 0.4 8.1e-49 166.5 0.4 2.1 2 0 0 2 2 2 1 Beige/BEACH domain DUF2732 PF10809.8 CUU99805.1 - 0.056 13.3 0.1 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) LMWPc PF01451.21 CUU99805.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase PARP_reg PF02877.14 CUU99806.1 - 1.8e-24 86.4 0.1 2.5e-23 82.7 0.1 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain GHMP_kinases_N PF00288.26 CUU99806.1 - 4.2e-06 26.9 0.8 9.7e-06 25.7 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CUU99806.1 - 2.1e-05 24.8 0.1 4.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ODAM PF15424.6 CUU99809.1 - 0.051 13.2 0.1 0.48 10.0 0.0 2.3 3 0 0 3 3 3 0 Odontogenic ameloblast-associated family Ribosomal_L6e PF01159.19 CUU99813.1 - 1.3e-18 67.6 3.7 1.3e-12 48.2 0.7 7.5 4 2 4 8 8 8 2 Ribosomal protein L6e Beach PF02138.18 CUU99817.1 - 5.9e-13 48.8 0.0 2e-12 47.1 0.0 1.9 3 0 0 3 3 3 1 Beige/BEACH domain RVT_1 PF00078.27 CUU99818.1 - 1.1e-14 54.5 0.2 1.8e-14 53.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RE_MjaI PF09568.10 CUU99818.1 - 0.038 13.8 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 MjaI restriction endonuclease Homeodomain PF00046.29 CUU99828.1 - 4.8e-19 68.0 4.9 1.3e-18 66.5 5.3 1.5 2 0 0 2 2 2 1 Homeodomain Auxin_canalis PF05703.11 CUU99828.1 - 0.021 14.8 0.4 0.025 14.5 0.4 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF1323 PF07037.11 CUU99828.1 - 0.068 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) HemY_N PF07219.13 CUU99828.1 - 0.14 12.3 0.7 0.23 11.7 0.3 1.5 1 1 0 1 1 1 0 HemY protein N-terminus PRIMA1 PF16101.5 CUU99829.1 - 0.037 14.1 5.8 0.049 13.7 5.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM119 PF15724.5 CUU99830.1 - 0.31 11.1 2.3 0.7 9.9 2.3 1.5 1 0 0 1 1 1 0 TMEM119 family Spc7_N PF15402.6 CUU99830.1 - 0.34 9.1 3.6 0.56 8.4 3.6 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1035 PF06281.12 CUU99838.1 - 2.1 8.4 5.7 8.4 6.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Mito_fiss_reg PF05308.11 CUU99839.1 - 6.7 6.7 8.5 7.1 6.6 8.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2 PF00096.26 CUU99843.1 - 0.051 14.0 1.9 0.051 14.0 1.9 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Presenilin PF01080.17 CUU99843.1 - 0.1 11.4 0.4 0.15 10.8 0.4 1.2 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CUU99843.1 - 0.22 11.5 0.7 0.48 10.3 0.5 1.6 1 1 0 1 1 1 0 N-glycosylation protein AP3D1 PF06375.11 CUU99843.1 - 0.34 11.1 19.5 0.61 10.3 19.5 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PPL5 PF18168.1 CUU99843.1 - 1.7 7.9 7.7 2.7 7.2 7.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Vfa1 PF08432.10 CUU99843.1 - 2.6 8.4 21.1 4.6 7.5 21.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 tRNA_bind_2 PF13725.6 CUU99846.1 - 0.038 13.7 1.0 0.079 12.6 0.1 1.8 2 0 0 2 2 2 0 Possible tRNA binding domain zf-C2H2 PF00096.26 CUU99848.1 - 1.5e-05 25.2 16.8 0.00011 22.5 4.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CUU99848.1 - 2.7e-05 24.4 18.7 0.00052 20.3 2.8 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CUU99848.1 - 0.0011 19.6 12.2 0.017 15.9 3.2 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CUU99848.1 - 0.16 12.3 3.2 2.1 8.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 CUU99848.1 - 0.45 10.2 1.7 0.84 9.3 1.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) S_100 PF01023.19 CUU99850.1 - 0.043 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Mycobact_memb PF05423.13 CUU99851.1 - 0.016 15.2 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Mycobacterium membrane protein DUF2469 PF10611.9 CUU99851.1 - 0.071 13.7 0.1 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2469) PRIMA1 PF16101.5 CUU99853.1 - 0.29 11.2 3.1 0.48 10.5 3.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMEM89 PF15098.6 CUU99857.1 - 0.14 12.3 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 TMEM89 protein family SOG2 PF10428.9 CUU99863.1 - 0.095 11.9 8.0 0.093 11.9 8.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RNA_pol_3_Rpc31 PF11705.8 CUU99863.1 - 0.9 9.7 2.2 0.64 10.2 0.7 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HiaBD2 PF15403.6 CUU99864.1 - 1.5 9.2 8.0 12 6.4 1.0 2.4 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) zf-C2H2 PF00096.26 CUU99869.1 - 0.055 13.9 1.9 0.055 13.9 1.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99869.1 - 1.1 10.3 6.9 0.2 12.6 1.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CUU99870.1 - 6.9e-10 38.8 41.7 0.00047 20.4 4.3 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CUU99870.1 - 2.8e-06 27.5 32.9 0.00053 20.3 5.4 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CUU99870.1 - 0.0011 19.6 37.6 0.051 14.4 3.8 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger DUF2225 PF09986.9 CUU99870.1 - 4.6 6.9 6.8 1.5 8.5 2.9 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SDF PF00375.18 CUU99872.1 - 4.4e-18 65.5 7.2 4.8e-18 65.4 7.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CEP44 PF15007.6 CUU99873.1 - 0.00069 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 DUF3311 PF11755.8 CUU99873.1 - 0.17 11.8 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Abhydrolase_2 PF02230.16 CUU99875.1 - 5.5e-05 23.1 0.1 0.0006 19.7 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Pkinase PF00069.25 CUU99876.1 - 1.9e-09 37.3 0.0 2.3e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99876.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Rad51 PF08423.11 CUU99877.1 - 5.4e-22 78.3 0.1 8e-15 54.8 0.0 2.0 1 1 1 2 2 2 2 Rad51 zf_C2H2_13 PF18508.1 CUU99877.1 - 0.092 12.4 1.2 0.15 11.7 1.2 1.3 1 0 0 1 1 1 0 Zinc finger domain ssDNA_TraI_N PF18272.1 CUU99877.1 - 0.16 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain HLH PF00010.26 CUU99878.1 - 7.3e-05 22.6 0.6 0.00013 21.9 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 CUU99879.1 - 0.00026 20.9 0.6 0.00026 20.9 0.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2956 PF11169.8 CUU99879.1 - 3 8.1 4.7 0.71 10.1 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) CAP PF00188.26 CUU99881.1 - 0.041 14.7 0.0 0.064 14.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.26 CUU99882.1 - 7.6e-09 36.5 7.7 0.00034 21.4 1.1 2.2 1 1 0 2 2 2 2 Cysteine-rich secretory protein family DUF956 PF06115.11 CUU99882.1 - 0.063 13.0 0.1 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF956) DUF3224 PF11528.8 CUU99882.1 - 0.12 12.2 0.1 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) Tox-WTIP PF15654.6 CUU99882.1 - 0.73 10.3 3.6 15 6.0 0.4 2.3 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif CAP PF00188.26 CUU99883.1 - 1.3e-20 74.5 2.6 1.8e-20 74.0 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 CUU99884.1 - 2.3e-08 34.9 2.7 4.6e-08 34.0 2.7 1.6 1 1 0 1 1 1 1 Cysteine-rich secretory protein family IL12 PF03039.14 CUU99885.1 - 0.17 11.2 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Interleukin-12 alpha subunit RVT_1 PF00078.27 CUU99887.1 - 9.5e-30 103.8 0.1 1.7e-29 102.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CUU99887.1 - 0.00015 22.4 0.0 0.87 10.3 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CUU99887.1 - 0.00017 22.1 0.0 0.25 11.9 0.0 3.2 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease RVP PF00077.20 CUU99887.1 - 0.0015 18.8 0.0 5 7.5 0.0 3.3 2 1 0 2 2 2 2 Retroviral aspartyl protease GFA PF04828.14 CUU99890.1 - 0.082 13.2 0.1 0.093 13.1 0.1 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF4604 PF15377.6 CUU99891.1 - 6 7.3 16.7 0.039 14.4 6.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Rad51 PF08423.11 CUU99892.1 - 1.2e-18 67.3 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Rad51 DNA_processg_A PF02481.15 CUU99892.1 - 0.081 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Rad51 PF08423.11 CUU99894.1 - 1.2e-18 67.3 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Rad51 DNA_processg_A PF02481.15 CUU99894.1 - 0.081 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Tetraspanin PF00335.20 CUU99900.1 - 0.61 9.8 13.8 0.74 9.5 13.8 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4064 PF13273.6 CUU99900.1 - 3.1 8.1 11.3 13 6.1 11.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Kelch_1 PF01344.25 CUU99901.1 - 0.27 10.9 1.6 0.86 9.2 0.1 2.6 2 2 0 2 2 2 0 Kelch motif zf-H2C2_2 PF13465.6 CUU99904.1 - 0.093 13.2 0.3 0.093 13.2 0.3 1.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 CUU99904.1 - 2.1 8.8 5.1 0.88 10.0 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rad51 PF08423.11 CUU99905.1 - 1.3e-22 80.3 0.0 1.6e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Rad51 SNF PF00209.18 CUU99907.1 - 0.0014 17.5 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family QVR PF17064.5 CUU99909.1 - 0.00046 20.4 1.4 0.00066 19.9 1.4 1.2 1 0 0 1 1 1 1 Sleepless protein UPAR_LY6 PF00021.21 CUU99909.1 - 0.0011 19.6 0.9 0.0019 18.8 0.9 1.4 1 1 0 1 1 1 1 u-PAR/Ly-6 domain Pkinase_Tyr PF07714.17 CUU99911.1 - 1.1e-52 178.8 0.0 1.3e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CUU99911.1 - 2.1e-18 66.6 0.0 2.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CUU99911.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CUU99911.1 - 0.063 13.2 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BPL_LplA_LipB PF03099.19 CUU99912.1 - 1.2e-05 25.2 0.0 2.2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FAF PF11250.8 CUU99913.1 - 0.041 14.1 1.9 0.13 12.6 1.9 1.8 1 1 0 1 1 1 0 Fantastic Four meristem regulator Connexin50 PF03509.14 CUU99913.1 - 0.1 13.4 0.1 0.95 10.3 0.1 2.1 2 0 0 2 2 2 0 Gap junction alpha-8 protein (Cx50) Exo_endo_phos_2 PF14529.6 CUU99916.1 - 1.3e-13 50.8 0.3 2.2e-13 50.1 0.3 1.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CUU99916.1 - 6.2e-05 22.6 0.0 7.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4704 PF15787.5 CUU99917.1 - 7.8e-10 38.4 0.4 9.6e-10 38.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Ribosomal_L37e PF01907.19 CUU99918.1 - 0.21 11.8 1.9 1.6 8.9 0.1 2.2 1 1 0 2 2 2 0 Ribosomal protein L37e DUF4817 PF16087.5 CUU99919.1 - 1.6e-07 31.0 0.3 1.6e-07 31.0 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain (DUF4817) DUF4704 PF15787.5 CUU99921.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Malic_M PF03949.15 CUU99923.1 - 1.3e-14 54.1 0.5 3.5e-13 49.4 0.0 2.0 1 1 1 2 2 2 2 Malic enzyme, NAD binding domain 53-BP1_Tudor PF09038.10 CUU99923.1 - 0.09 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DIL PF01843.19 CUU99924.1 - 2e-05 24.8 0.9 2e-05 24.8 0.9 2.1 2 1 0 2 2 2 1 DIL domain F-box_4 PF15966.5 CUU99927.1 - 3.6e-35 120.3 0.0 5.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 F-box PRANC PF09372.10 CUU99927.1 - 0.0053 17.0 0.0 0.0081 16.5 0.0 1.3 1 0 0 1 1 1 1 PRANC domain F-box PF00646.33 CUU99927.1 - 0.0072 16.2 0.6 0.016 15.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain Cupin_8 PF13621.6 CUU99928.1 - 6.7e-35 121.0 0.0 1.1e-34 120.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CUU99928.1 - 0.0039 17.6 0.1 0.0074 16.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CUU99928.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily protein Telomere_res PF16684.5 CUU99929.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Telomere resolvase DUF3821 PF12863.7 CUU99930.1 - 0.15 12.0 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) HTH_48 PF17906.1 CUU99933.1 - 1.6e-05 24.9 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain in Mos1 transposase TetR_C_26 PF17934.1 CUU99944.1 - 0.052 13.9 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribonuc_red_lgC PF02867.15 CUU99946.1 - 0.0017 17.0 0.1 0.0037 15.9 0.0 1.5 1 1 1 2 2 2 1 Ribonucleotide reductase, barrel domain CLZ PF16526.5 CUU99948.1 - 6.4e-20 71.3 6.9 9.6e-20 70.7 6.9 1.3 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels cNMP_binding PF00027.29 CUU99948.1 - 0.049 13.7 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain CAP_N PF01213.19 CUU99949.1 - 3.9 6.8 6.0 6.3 6.2 6.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SMN PF06003.12 CUU99949.1 - 4.1 6.6 4.8 5.5 6.2 4.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GCP_N_terminal PF17681.1 CUU99951.1 - 2.3e-31 109.6 0.1 1e-30 107.4 0.1 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CUU99951.1 - 5.8e-30 104.8 9.4 3.3e-29 102.3 8.3 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal IRK PF01007.20 CUU99951.1 - 0.02 14.7 2.1 0.9 9.4 0.3 2.6 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain RPN7 PF10602.9 CUU99951.1 - 0.11 12.2 0.6 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF3535 PF12054.8 CUU99951.1 - 0.13 11.5 0.8 0.54 9.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) DEAD PF00270.29 CUU99952.1 - 8.7e-19 68.0 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CUU99952.1 - 1.2e-07 31.8 0.1 3.1e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CUU99952.1 - 0.011 15.7 0.6 0.068 13.1 0.0 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CUU99952.1 - 0.12 12.1 0.0 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 CUU99952.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein MFS_2 PF13347.6 CUU99953.1 - 7.6e-47 159.8 16.0 8.5e-47 159.7 16.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CUU99953.1 - 4.6e-08 32.4 10.7 4.6e-08 32.4 10.7 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 CUU99953.1 - 0.46 10.8 8.4 4.3 7.7 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) MFS_2 PF13347.6 CUU99954.1 - 1.2e-48 165.7 9.7 1.4e-48 165.5 9.7 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1772 PF08592.11 CUU99954.1 - 0.3 11.4 4.9 0.48 10.7 1.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) SEA PF01390.20 CUU99955.1 - 0.19 11.9 1.1 0.32 11.1 0.1 2.0 2 1 0 2 2 2 0 SEA domain zf-C2H2 PF00096.26 CUU99956.1 - 3.8e-15 55.4 21.4 1.6e-06 28.2 0.5 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CUU99956.1 - 1.7e-13 50.1 21.2 9e-05 23.0 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CUU99956.1 - 1.2e-12 47.6 17.6 2.1e-05 24.8 0.2 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 CUU99956.1 - 1.3e-11 44.0 15.6 0.0013 18.5 4.3 3.3 3 0 0 3 3 3 3 zinc-finger C2H2-type zf-met PF12874.7 CUU99956.1 - 1.2e-06 28.7 16.4 0.033 14.6 0.7 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CUU99956.1 - 9.5e-06 25.8 12.6 0.012 15.9 0.9 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CUU99956.1 - 7.5e-05 22.6 19.5 0.07 13.2 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger C1_4 PF07975.12 CUU99956.1 - 0.00029 21.0 3.2 0.12 12.6 2.3 2.4 2 0 0 2 2 2 1 TFIIH C1-like domain zf-H2C2_5 PF13909.6 CUU99956.1 - 0.00034 20.3 23.3 0.16 11.7 1.4 4.0 3 2 0 3 3 3 2 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 CUU99956.1 - 0.0014 18.5 7.4 0.82 9.6 0.1 3.2 3 0 0 3 3 3 2 zinc-ribbon domain zf-C2H2_3rep PF18868.1 CUU99956.1 - 0.0021 18.7 7.9 0.076 13.7 8.0 2.7 1 1 2 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 CUU99956.1 - 0.0024 17.4 7.5 0.06 12.9 0.3 3.2 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CUU99956.1 - 0.0034 17.5 7.3 1.3 9.2 0.3 3.2 3 0 0 3 3 3 1 Zinc ribbon domain TFIIS_C PF01096.18 CUU99956.1 - 0.0039 17.0 4.5 3.7 7.5 0.2 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) C1_1 PF00130.22 CUU99956.1 - 0.0043 16.9 5.5 0.054 13.4 0.9 2.4 1 1 2 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-DNL PF05180.12 CUU99956.1 - 0.0056 16.6 5.3 0.038 13.9 2.9 2.3 2 0 0 2 2 2 1 DNL zinc finger zf-C2H2_8 PF15909.5 CUU99956.1 - 0.016 15.5 1.8 0.016 15.5 1.8 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CUU99956.1 - 0.021 15.1 14.5 2.3 8.6 0.8 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CUU99956.1 - 0.024 14.9 10.9 0.6 10.5 3.1 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 CUU99956.1 - 0.035 14.3 10.0 1.1 9.5 0.1 2.8 2 1 0 2 2 2 0 LIM domain Yippee-Mis18 PF03226.14 CUU99956.1 - 0.069 13.4 6.8 2.5 8.4 0.0 2.9 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RGCC PF15151.6 CUU99956.1 - 0.079 13.2 1.7 0.18 12.0 1.0 1.7 1 1 1 2 2 2 0 Response gene to complement 32 protein family OrsD PF12013.8 CUU99956.1 - 0.11 13.0 9.5 0.69 10.4 0.0 3.0 2 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2HE PF16278.5 CUU99956.1 - 0.14 12.6 14.6 3.4 8.2 0.8 3.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 CUU99956.1 - 0.14 12.9 7.6 3 8.6 6.0 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf-AN1 PF01428.16 CUU99956.1 - 0.15 12.2 10.3 9.6 6.5 0.1 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger Elf1 PF05129.13 CUU99956.1 - 0.16 12.1 9.2 0.43 10.7 0.6 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF629 PF04780.12 CUU99956.1 - 0.17 10.4 15.0 1.5 7.3 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Zn_Tnp_IS1595 PF12760.7 CUU99956.1 - 0.22 11.5 9.4 2.7 8.1 0.0 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain BolA PF01722.18 CUU99956.1 - 0.25 11.7 3.6 1.1 9.6 0.5 2.6 1 1 2 3 3 3 0 BolA-like protein Zn_ribbon_SprT PF17283.2 CUU99956.1 - 0.29 11.1 12.5 1.5 8.8 1.1 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF2197 PF09963.9 CUU99956.1 - 0.34 11.2 8.0 8.5 6.7 0.7 3.2 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zinc-ribbons_6 PF07191.12 CUU99956.1 - 0.5 10.4 9.2 1.2 9.1 4.4 2.4 1 1 2 3 3 3 0 zinc-ribbons zf_C2H2_ZHX PF18387.1 CUU99956.1 - 0.5 10.0 11.1 1.5 8.5 0.1 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DNA_RNApol_7kD PF03604.13 CUU99956.1 - 0.97 9.2 3.7 42 3.9 0.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-LYAR PF08790.11 CUU99956.1 - 1.2 9.0 20.1 2.5 8.1 0.3 3.7 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger Sprouty PF05210.13 CUU99956.1 - 1.3 9.4 8.6 1.8 9.0 2.6 2.2 1 1 1 2 2 2 0 Sprouty protein (Spry) HypA PF01155.19 CUU99956.1 - 1.9 8.6 6.8 5.7 7.0 2.5 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2256 PF10013.9 CUU99956.1 - 2 8.6 7.2 5.3 7.2 0.5 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 CUU99956.1 - 2.1 8.5 10.5 2.3 8.4 0.2 3.0 3 1 0 3 3 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-TFIIB PF13453.6 CUU99956.1 - 2.4 7.5 6.1 25 4.3 2.7 3.0 3 1 0 3 3 3 0 Transcription factor zinc-finger DpnI PF06044.12 CUU99956.1 - 3.1 7.4 5.6 9.2 5.9 0.1 2.7 1 1 2 3 3 3 0 Dam-replacing family XPA_N PF01286.18 CUU99956.1 - 3.6 7.7 7.4 11 6.2 0.4 3.0 3 0 0 3 3 3 0 XPA protein N-terminal Actin_micro PF17003.5 CUU99956.1 - 8.4 5.5 10.7 8.9 5.4 2.4 2.6 1 1 1 2 2 2 0 Putative actin-like family HTH_20 PF12840.7 CUU99958.1 - 0.046 13.8 0.3 0.79 9.8 0.1 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain Pkinase PF00069.25 CUU99961.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CUU99961.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4704 PF15787.5 CUU99964.1 - 0.19 10.9 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Kelch_1 PF01344.25 CUU99965.1 - 1.3e-13 50.3 0.1 5.1e-10 38.8 0.0 2.8 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CUU99965.1 - 5.7e-09 35.9 0.0 3.9e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CUU99965.1 - 1.4e-06 28.0 0.1 0.00097 19.0 0.0 2.9 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CUU99965.1 - 3.1e-06 27.1 0.0 1.1e-05 25.4 0.0 1.9 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CUU99965.1 - 2.4e-05 24.5 0.2 0.0013 19.0 0.0 3.0 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CUU99965.1 - 0.00076 19.4 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Kelch motif BNR_4 PF15892.5 CUU99965.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member TMPIT PF07851.13 CUU99970.1 - 0.023 14.0 1.0 0.031 13.5 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3959 PF13105.6 CUU99970.1 - 0.3 10.6 5.5 0.38 10.2 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Claudin_2 PF13903.6 CUU99970.1 - 2.8 7.7 8.0 1.6 8.5 6.0 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DAGK_prokar PF01219.19 CUU99970.1 - 3.4 7.6 8.2 0.24 11.3 0.5 2.7 1 1 3 4 4 4 0 Prokaryotic diacylglycerol kinase Ank_2 PF12796.7 CUU99971.1 - 2.9e-23 82.3 0.9 5.8e-09 36.4 0.2 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CUU99971.1 - 4.7e-13 49.4 1.6 0.01 16.4 0.1 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CUU99971.1 - 1.1e-12 47.9 1.4 0.00095 19.4 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CUU99971.1 - 1.2e-10 40.6 1.7 2.9 8.8 0.0 6.0 5 1 1 6 6 6 4 Ankyrin repeat Ank PF00023.30 CUU99971.1 - 6.7e-08 32.6 3.6 0.56 10.8 0.2 5.8 5 1 1 6 6 6 2 Ankyrin repeat SesA PF17107.5 CUU99972.1 - 0.0043 17.2 0.1 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_2 PF07719.17 CUU99972.1 - 0.058 13.5 0.5 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat pPIWI_RE_X PF13111.6 CUU99974.1 - 0.016 14.4 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain MS_channel PF00924.18 CUU99974.1 - 0.018 14.6 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel Coat_F PF07875.12 CUU99974.1 - 0.061 13.6 0.5 0.11 12.7 0.5 1.5 1 1 0 1 1 1 0 Coat F domain DUF2162 PF09930.9 CUU99975.1 - 0.34 10.3 13.1 0.14 11.5 10.9 1.6 1 1 1 2 2 2 0 Predicted transporter (DUF2162) Tetraspanin PF00335.20 CUU99975.1 - 0.69 9.6 20.6 1.2 8.9 1.2 2.1 2 0 0 2 2 2 0 Tetraspanin family Gemini_mov PF01708.16 CUU99975.1 - 2.1 8.1 4.0 11 5.9 0.2 2.5 2 0 0 2 2 2 0 Geminivirus putative movement protein Homeodomain PF00046.29 CUU99976.1 - 8.4e-19 67.2 3.8 8.4e-19 67.2 3.8 1.6 2 0 0 2 2 2 1 Homeodomain Y_phosphatase PF00102.27 CUU99976.1 - 4.2e-16 59.2 0.1 5.7e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Auxin_canalis PF05703.11 CUU99976.1 - 0.18 11.7 1.9 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Auxin canalisation DUF4744 PF15918.5 CUU99977.1 - 3 8.8 4.5 30 5.5 4.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Hymenolepis_microstoma-HMIC002/GCA_000469805.2_HMIC002_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Hymenolepis_microstoma-HMIC002/GCA_000469805.2_HMIC002_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Hymenolepis_microstoma-HMIC002/GCA_000469805.2_HMIC002_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Plathelminthes/Hymenolepis_microstoma-HMIC002/GCA_000469805.2_HMIC002_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 20:16:33 2019 # [ok]